# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Lactamase_B PF00753.27 KKK40112.1 - 7.7e-18 65.2 0.0 9.4e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK40112.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Toxin-deaminase PF14424.6 KKK40112.1 - 0.028 14.5 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Aldo_ket_red PF00248.21 KKK40114.1 - 1e-38 133.2 0.4 1.9e-38 132.3 0.4 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Fer4_17 PF13534.6 KKK40114.1 - 1.1e-10 41.9 2.8 2.9e-10 40.5 2.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK40114.1 - 1.3e-09 38.0 2.0 3.3e-09 36.8 2.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK40114.1 - 2.6e-06 27.8 1.0 6.2e-06 26.6 1.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK40114.1 - 6.6e-06 26.3 0.4 0.0057 16.8 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK40114.1 - 1.3e-05 25.2 2.8 3.7e-05 23.7 2.9 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK40114.1 - 0.00032 21.2 6.0 0.0017 18.9 6.1 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 KKK40114.1 - 0.00041 20.1 0.2 0.00041 20.1 0.2 2.1 2 0 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_22 PF17179.4 KKK40114.1 - 0.0009 20.0 1.5 0.67 10.8 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK40114.1 - 0.0057 16.4 2.3 0.0057 16.4 2.3 2.7 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 KKK40114.1 - 0.038 14.1 2.3 0.038 14.1 2.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.6 KKK40114.1 - 0.045 14.7 0.5 0.045 14.7 0.5 2.9 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK40114.1 - 0.069 13.3 6.4 0.47 10.6 1.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain GGGtGRT PF14057.6 KKK40114.1 - 0.079 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 GGGtGRT protein Sacchrp_dh_NADP PF03435.18 KKK40114.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fer4_4 PF12800.7 KKK40114.1 - 0.17 12.4 10.7 0.093 13.3 2.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK40114.1 - 5.5 7.3 15.7 0.29 11.3 2.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain NifQ PF04891.12 KKK40115.1 - 0.4 11.0 3.4 0.49 10.7 3.4 1.1 1 0 0 1 1 1 0 NifQ NUDIX PF00293.28 KKK40116.1 - 1.7e-11 44.2 0.0 2.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KKK40117.1 - 3.5e-13 49.7 0.0 5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain THAP PF05485.12 KKK40118.1 - 0.025 15.5 1.1 0.047 14.6 1.1 1.5 1 1 0 1 1 1 0 THAP domain zinc_ribbon_2 PF13240.6 KKK40120.1 - 0.00027 20.6 4.0 0.00055 19.6 4.0 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK40120.1 - 0.00028 20.2 3.4 0.00048 19.4 3.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK40120.1 - 0.0014 18.6 0.7 0.0026 17.8 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KKK40120.1 - 0.0054 16.6 3.6 1.1 9.3 0.1 2.4 2 0 0 2 2 2 2 Nudix N-terminal NOB1_Zn_bind PF08772.11 KKK40120.1 - 0.57 10.4 5.5 9.7 6.4 1.3 2.9 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_15 PF17032.5 KKK40120.1 - 8.3 7.2 7.8 0.82 10.5 2.3 2.2 2 1 0 2 2 2 0 zinc-ribbon family adh_short PF00106.25 KKK40121.1 - 1.8e-46 158.1 1.0 2.5e-46 157.6 0.5 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK40121.1 - 3.8e-27 95.4 0.0 5.2e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK40121.1 - 5.2e-10 39.5 0.2 7.9e-10 38.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK40121.1 - 0.0023 17.1 0.2 0.0028 16.8 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KKK40121.1 - 0.0033 16.9 0.2 0.037 13.5 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK40121.1 - 0.0058 16.5 0.1 0.0065 16.4 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Amido_AtzD_TrzD PF09663.10 KKK40121.1 - 0.025 13.6 0.0 3.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Sacchrp_dh_NADP PF03435.18 KKK40121.1 - 0.041 14.1 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KKK40121.1 - 0.062 13.2 1.6 0.91 9.4 0.1 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GTP_EFTU PF00009.27 KKK40122.1 - 7.4e-32 110.5 0.6 1.2e-31 109.8 0.6 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKK40122.1 - 2e-08 34.5 1.6 4.3e-08 33.4 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK40122.1 - 3.8e-06 27.0 0.2 1.3e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK40122.1 - 0.00053 19.2 1.3 0.0059 15.8 0.7 2.1 2 0 0 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 KKK40122.1 - 0.0041 16.7 0.1 0.011 15.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.6 KKK40122.1 - 0.0044 16.9 1.6 0.012 15.4 0.1 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 4 Robl_LC7 PF03259.17 KKK40123.1 - 4.6e-10 39.1 0.1 6.9e-10 38.6 0.1 1.4 1 1 0 1 1 1 1 Roadblock/LC7 domain Bmt2 PF11968.8 KKK40124.1 - 0.15 11.9 0.2 0.2 11.5 0.2 1.1 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 LRR_4 PF12799.7 KKK40126.1 - 2.8e-13 49.8 24.7 4.2e-06 27.0 3.2 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK40126.1 - 4.3e-13 48.8 5.2 1.3e-08 34.5 2.2 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 KKK40126.1 - 0.0018 17.8 0.7 0.003 17.1 0.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KKK40126.1 - 0.0044 17.4 9.9 0.77 10.5 0.3 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_2 PF07723.13 KKK40126.1 - 0.029 15.0 0.5 15 6.5 0.1 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat AHSA1 PF08327.11 KKK40127.1 - 4.3e-10 39.9 0.8 5.4e-10 39.6 0.8 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Stealth_CR1 PF17101.5 KKK40127.1 - 0.32 10.8 2.1 0.32 10.8 0.8 1.7 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 Pyr_redox_2 PF07992.14 KKK40130.1 - 1.5e-18 67.0 0.0 9.9e-18 64.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK40130.1 - 4.2e-08 33.6 1.3 0.00023 21.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK40130.1 - 3.8e-06 26.4 1.3 9.7e-05 21.8 1.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK40130.1 - 0.053 13.1 0.7 1 8.9 0.0 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pedibin PF08182.11 KKK40130.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family Polbeta PF18765.1 KKK40131.1 - 4.8e-05 23.4 0.2 0.00015 21.8 0.2 2.0 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK40131.1 - 0.00052 20.3 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Suv3_N PF18114.1 KKK40131.1 - 0.00092 19.3 0.3 0.0028 17.8 0.3 1.9 1 0 0 1 1 1 1 Suv3 helical N-terminal domain NOG1_N PF17835.1 KKK40132.1 - 0.013 15.5 1.4 0.021 14.8 1.4 1.5 1 1 0 1 1 1 0 NOG1 N-terminal helical domain GCIP PF13324.6 KKK40134.1 - 0.065 12.8 2.2 0.073 12.7 2.2 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting MalF_P2 PF14785.6 KKK40134.1 - 0.099 12.7 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain 4HB_MCP_1 PF12729.7 KKK40134.1 - 0.12 11.9 6.4 0.74 9.3 1.1 2.0 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction DUF4355 PF14265.6 KKK40134.1 - 0.37 11.0 7.1 0.2 11.9 5.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) tRNA-synt_2c PF01411.19 KKK40137.1 - 6.2e-75 252.8 0.0 1e-74 252.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KKK40137.1 - 2.9e-12 46.5 0.9 7.7e-12 45.1 0.9 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KKK40137.1 - 3e-09 37.4 0.2 3e-09 37.4 0.2 2.8 3 0 0 3 3 3 1 DHHA1 domain tRNA-synt_2e PF02091.15 KKK40137.1 - 0.0043 16.3 0.0 0.0097 15.2 0.0 1.5 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit DUF2935 PF11155.8 KKK40137.1 - 0.2 12.0 2.9 1.4 9.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) Med26 PF08711.11 KKK40137.1 - 0.32 11.1 3.6 0.33 11.0 0.8 2.6 2 0 0 2 2 2 0 TFIIS helical bundle-like domain MADF_DNA_bdg PF10545.9 KKK40137.1 - 0.65 10.4 2.7 8.9 6.7 0.0 3.5 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like CdvA PF18822.1 KKK40137.1 - 0.78 9.6 8.6 4.7 7.1 1.1 4.0 3 1 1 4 4 4 0 CdvA-like coiled-coil domain Metallophos PF00149.28 KKK40139.1 - 1.8e-14 54.7 0.2 9.8e-14 52.3 0.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK40139.1 - 4.2e-12 46.6 0.0 5.9e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KKK40139.1 - 0.0053 16.1 0.0 0.033 13.5 0.0 2.1 1 1 1 2 2 2 1 Metallophosphoesterase, calcineurin superfamily PhoD PF09423.10 KKK40139.1 - 0.02 13.9 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase FeoB_N PF02421.18 KKK40139.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF2292 PF10055.9 KKK40139.1 - 0.52 10.0 3.7 1.7 8.4 1.9 2.6 2 1 0 2 2 2 0 Uncharacterized small protein (DUF2292) NUDIX PF00293.28 KKK40140.1 - 5.7e-20 71.7 0.0 7.1e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Glyoxalase PF00903.25 KKK40141.1 - 0.003 17.7 0.1 0.0058 16.8 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily tRNA_deacylase PF04414.12 KKK40144.1 - 4.5e-57 192.9 0.0 5.3e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase Zip PF02535.22 KKK40145.1 - 3.8e-06 26.4 6.5 0.0023 17.2 0.4 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Neur_chan_memb PF02932.16 KKK40145.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.7 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region 60KD_IMP PF02096.20 KKK40145.1 - 1.4 8.8 8.8 0.14 12.1 1.6 2.5 2 2 0 2 2 2 0 60Kd inner membrane protein PRA1 PF03208.19 KKK40145.1 - 8.6 6.0 14.9 0.92 9.1 2.1 2.8 2 1 0 2 2 2 0 PRA1 family protein HTH_24 PF13412.6 KKK40146.1 - 6.1e-06 25.7 0.2 9.8e-06 25.0 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK40146.1 - 1.1e-05 25.1 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KKK40146.1 - 3e-05 23.9 0.2 0.00017 21.5 0.1 2.1 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain AsnC_trans_reg2 PF17805.1 KKK40146.1 - 0.048 13.8 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 AsnC-like ligand binding domain TetR_N PF00440.23 KKK40148.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family zf-Di19 PF05605.12 KKK40148.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding NPV_P10 PF05531.12 KKK40149.1 - 0.0092 16.4 11.9 9.6 6.8 0.4 4.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 KKK40149.1 - 0.013 15.5 25.8 0.013 15.5 24.4 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T3SSipB PF16535.5 KKK40149.1 - 0.013 16.0 4.2 0.013 16.0 4.2 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB MarR PF01047.22 KKK40149.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 MarR family Sec8_exocyst PF04048.14 KKK40149.1 - 0.019 14.8 11.6 0.023 14.6 3.4 3.2 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain TMF_TATA_bd PF12325.8 KKK40149.1 - 0.039 14.2 25.7 0.72 10.1 12.3 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 KKK40149.1 - 0.091 12.8 6.9 0.043 13.9 1.8 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HalX PF08663.10 KKK40149.1 - 0.12 12.7 5.0 1.6 9.1 0.0 3.5 2 1 1 3 3 3 0 HalX domain Spc7 PF08317.11 KKK40149.1 - 0.12 11.2 25.9 0.017 14.0 11.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 KKK40149.1 - 0.17 12.1 22.2 9.8 6.3 22.2 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 KKK40149.1 - 0.19 12.0 23.9 1.3 9.3 7.9 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 KKK40149.1 - 0.23 11.0 23.7 0.046 13.3 9.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF4201 PF13870.6 KKK40149.1 - 0.29 10.9 21.5 0.39 10.4 7.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 KKK40149.1 - 0.47 9.8 13.6 0.036 13.4 2.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KKK40149.1 - 0.6 10.2 9.7 0.53 10.4 1.6 3.0 2 1 1 3 3 3 0 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 KKK40149.1 - 0.64 10.1 29.8 2.6 8.1 7.9 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KKK40149.1 - 0.75 9.8 14.7 0.039 14.0 2.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Enkurin PF13864.6 KKK40149.1 - 0.98 9.9 18.6 0.17 12.3 6.3 2.9 2 1 1 3 3 3 0 Calmodulin-binding FliT PF05400.13 KKK40149.1 - 1.6 9.6 12.4 1.9 9.4 0.6 3.6 3 1 1 4 4 4 0 Flagellar protein FliT DUF724 PF05266.14 KKK40149.1 - 1.6 8.5 25.1 0.62 9.9 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Mt_ATP-synt_D PF05873.12 KKK40149.1 - 2 8.3 18.2 8.3 6.2 9.6 2.9 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) GAS PF13851.6 KKK40149.1 - 2 7.7 23.7 0.2 11.0 11.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KKK40149.1 - 2.1 8.8 23.7 4.9 7.5 23.5 1.7 1 1 0 1 1 1 0 Fez1 KASH_CCD PF14662.6 KKK40149.1 - 4.2 7.1 26.7 0.94 9.3 8.8 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 KKK40149.1 - 5.4 6.4 26.6 1.2 8.6 10.7 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 HSBP1 PF06825.12 KKK40149.1 - 8.4 6.3 14.9 1.3 9.0 0.6 4.5 5 0 0 5 5 5 0 Heat shock factor binding protein 1 DUF4435 PF14491.6 KKK40149.1 - 9.5 6.0 17.6 0.065 13.1 6.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4435) Big_3_2 PF12245.8 KKK40150.1 - 0.0016 18.7 0.0 0.002 18.4 0.0 1.2 1 1 0 1 1 1 1 Bacterial Ig-like domain Vut_1 PF02592.15 KKK40154.1 - 8e-08 32.7 3.3 9.3e-08 32.5 3.3 1.1 1 0 0 1 1 1 1 Putative vitamin uptake transporter QueT PF06177.11 KKK40155.1 - 2.6e-18 66.8 20.3 3.2e-18 66.4 20.3 1.0 1 0 0 1 1 1 1 QueT transporter ETRAMP PF09716.10 KKK40155.1 - 0.034 14.2 0.3 0.034 14.2 0.3 2.2 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ECF_trnsprt PF12822.7 KKK40155.1 - 0.1 12.7 25.2 0.13 12.4 25.2 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component HMGL-like PF00682.19 KKK40156.1 - 1.1e-42 146.4 0.0 1.6e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Methyltr_RsmB-F PF01189.17 KKK40157.1 - 1.1e-53 181.9 0.0 1.5e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KKK40157.1 - 3.6e-05 23.6 0.0 7.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KKK40157.1 - 5.4e-05 23.4 0.0 8.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2431 PF10354.9 KKK40157.1 - 0.0037 17.5 0.0 0.015 15.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) CPSase_L_D3 PF02787.19 KKK40157.1 - 0.058 13.8 1.1 0.12 12.7 1.1 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF3786 PF12654.7 KKK40158.1 - 0.079 12.6 0.1 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Arf PF00025.21 KKK40160.1 - 1.2e-18 67.2 0.1 1.4e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK40160.1 - 4e-14 52.9 0.0 5.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK40160.1 - 1.7e-11 44.0 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK40160.1 - 1.7e-07 30.9 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK40160.1 - 3.5e-05 23.4 0.3 0.081 12.4 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KKK40160.1 - 0.00021 20.8 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KKK40160.1 - 0.00022 21.3 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KKK40160.1 - 0.00036 20.3 0.3 0.0021 17.8 0.3 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KKK40160.1 - 0.00098 19.7 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KKK40160.1 - 0.0058 16.1 0.0 0.0081 15.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK40160.1 - 0.01 15.0 1.1 0.62 9.2 0.2 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 KKK40160.1 - 0.018 15.3 0.0 0.069 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK40160.1 - 0.029 14.1 0.1 4.5 7.0 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 KKK40160.1 - 0.048 13.4 0.0 5.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KKK40160.1 - 0.077 13.4 0.1 0.39 11.1 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4286 PF14114.6 KKK40161.1 - 0.0019 18.7 2.4 0.12 12.9 2.4 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4286) DUF3829 PF12889.7 KKK40161.1 - 0.012 15.1 0.2 0.018 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Phage_integrase PF00589.22 KKK40162.1 - 1.4e-16 60.8 0.1 2.2e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 KKK40162.1 - 0.0012 19.3 3.1 0.0024 18.3 0.3 2.6 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_6 PF18644.1 KKK40162.1 - 0.65 10.0 6.7 1.3 9.1 0.1 3.7 3 1 0 4 4 4 0 Phage integrase SAM-like domain GXGXG PF01493.19 KKK40167.1 - 5.3e-05 22.9 0.4 6.4e-05 22.6 0.4 1.2 1 0 0 1 1 1 1 GXGXG motif zinc_ribbon_2 PF13240.6 KKK40169.1 - 7.4e-06 25.5 5.1 1.1e-05 25.0 5.1 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK40169.1 - 3.3e-05 23.8 0.8 4.9e-05 23.3 0.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK40169.1 - 4e-05 24.3 0.5 5.1e-05 23.9 0.5 1.2 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 KKK40169.1 - 0.00075 19.5 0.9 0.0014 18.6 0.4 1.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.6 KKK40169.1 - 0.026 14.4 3.1 1.8 8.6 0.2 2.2 2 0 0 2 2 2 0 Nudix N-terminal DUF2321 PF10083.9 KKK40169.1 - 0.04 13.6 3.1 0.14 11.8 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) SUR7 PF06687.12 KKK40169.1 - 0.19 11.3 7.4 0.25 10.9 1.2 2.1 1 1 1 2 2 2 0 SUR7/PalI family YhfH PF14149.6 KKK40169.1 - 0.32 11.0 3.0 9.8 6.3 0.3 2.3 1 1 1 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.10 KKK40169.1 - 0.33 11.1 2.0 20 5.4 0.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KKK40169.1 - 0.37 10.6 6.4 1.2 9.0 6.4 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 KKK40169.1 - 0.81 9.2 5.7 2.4 7.7 5.7 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF2070 PF09843.9 KKK40169.1 - 7 4.8 8.8 8.8 4.5 8.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DHHC PF01529.20 KKK40169.1 - 8.8 6.4 11.3 0.35 11.0 1.1 2.6 2 1 1 3 3 3 0 DHHC palmitoyltransferase FdhD-NarQ PF02634.15 KKK40170.1 - 2.7e-66 223.6 0.0 3.1e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family Rubredoxin_C PF18267.1 KKK40170.1 - 0.038 13.9 0.1 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain BacA PF02673.18 KKK40175.1 - 9.9e-36 123.8 14.9 1.2e-35 123.5 14.9 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA Ins134_P3_kin PF05770.11 KKK40176.1 - 5.3e-09 35.9 2.5 1.9e-06 27.6 0.3 2.5 1 1 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Inos-1-P_synth PF01658.17 KKK40177.1 - 3.1e-19 69.2 0.0 5.3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 KKK40177.1 - 0.00069 19.1 0.0 0.0024 17.3 0.0 1.8 2 1 1 3 3 3 1 Myo-inositol-1-phosphate synthase DUF1611_N PF17396.2 KKK40177.1 - 0.018 15.2 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Ins134_P3_kin PF05770.11 KKK40178.1 - 1.1e-07 31.5 1.4 5.3e-06 26.1 0.2 2.3 1 1 1 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain TTL PF03133.15 KKK40178.1 - 0.00045 19.4 0.0 0.0016 17.7 0.0 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family RimK PF08443.11 KKK40178.1 - 0.016 14.9 0.0 0.037 13.6 0.0 1.6 2 0 0 2 2 2 0 RimK-like ATP-grasp domain PBP_like PF12727.7 KKK40178.1 - 0.23 10.5 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain Dala_Dala_lig_C PF07478.13 KKK40179.1 - 0.0062 16.1 0.1 0.016 14.8 0.1 1.8 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus RimK PF08443.11 KKK40179.1 - 0.027 14.0 0.0 0.094 12.3 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KKK40180.1 - 4.8e-05 23.5 0.0 8.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KKK40180.1 - 0.0012 18.4 0.2 0.0055 16.3 0.0 2.2 2 1 1 3 3 3 1 ATP-grasp domain ATP-grasp PF02222.22 KKK40180.1 - 0.0043 16.6 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 KKK40180.1 - 0.18 11.2 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HAD_2 PF13419.6 KKK40181.1 - 4e-13 49.8 0.6 4e-13 49.8 0.6 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK40181.1 - 2.7e-09 37.6 0.0 3.6e-08 33.9 0.0 2.5 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase OmpH PF03938.14 KKK40181.1 - 0.0015 18.9 17.2 0.0035 17.7 17.2 1.6 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) EMC3_TMCO1 PF01956.16 KKK40181.1 - 7.3 6.3 13.7 15 5.2 13.7 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FKBP26_C PF18046.1 KKK40182.1 - 5.2e-09 36.1 2.9 5.2e-09 36.1 2.9 2.6 2 0 0 2 2 2 1 FKBP26_C-terminal HHH_5 PF14520.6 KKK40182.1 - 7.5e-09 36.1 4.9 7.5e-09 36.1 4.9 3.0 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 KKK40182.1 - 1.1e-06 28.2 0.6 3.1e-05 23.6 0.2 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif FKBP_C PF00254.28 KKK40182.1 - 5.3e-06 26.7 3.3 7.9e-05 22.9 2.8 2.6 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RNA_pol_A_CTD PF03118.15 KKK40182.1 - 0.00039 20.1 0.2 0.00039 20.1 0.2 2.6 2 0 0 2 2 2 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH_2 PF12826.7 KKK40182.1 - 0.0012 18.9 0.1 0.0036 17.3 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif IMS_HHH PF11798.8 KKK40182.1 - 0.0045 17.2 0.7 1.7 9.1 0.0 3.1 3 0 0 3 3 2 1 IMS family HHH motif HHH_8 PF14716.6 KKK40182.1 - 0.0066 16.8 0.3 0.0066 16.8 0.3 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain DUF4332 PF14229.6 KKK40182.1 - 0.027 14.7 1.3 0.053 13.8 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4332) SAA PF00277.18 KKK40182.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Serum amyloid A protein HHH_3 PF12836.7 KKK40182.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.4 3 0 0 3 3 2 0 Helix-hairpin-helix motif Myotoxins PF00819.17 KKK40182.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Myotoxin, crotamine SYCP2_SLD PF18584.1 KKK40182.1 - 0.13 12.5 0.3 0.13 12.5 0.3 2.2 2 0 0 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain Ribosomal_S13 PF00416.22 KKK40182.1 - 0.16 12.3 8.5 1.3 9.4 5.5 3.2 2 1 1 3 3 3 0 Ribosomal protein S13/S18 5_3_exonuc PF01367.20 KKK40182.1 - 0.94 10.1 11.3 0.14 12.8 5.0 2.8 2 2 1 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold DNA_pol3_beta_3 PF02768.15 KKK40188.1 - 0.13 12.1 2.5 0.28 11.0 2.5 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain HGD-D PF06050.13 KKK40190.1 - 9.8e-14 51.8 0.0 1.3e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component Cnd1 PF12717.7 KKK40191.1 - 0.0044 17.1 0.9 0.0077 16.3 0.8 1.3 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Baculo_PEP_C PF04513.12 KKK40191.1 - 0.019 15.0 1.1 0.036 14.1 1.1 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MukF_M PF17192.4 KKK40191.1 - 0.11 12.2 0.6 0.63 9.8 0.6 2.0 1 1 0 1 1 1 0 MukF middle domain Prominin PF05478.11 KKK40191.1 - 0.34 8.8 1.3 0.62 8.0 0.8 1.3 1 1 0 1 1 1 0 Prominin FlaC_arch PF05377.11 KKK40191.1 - 0.38 11.2 5.4 5.4 7.5 2.8 3.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) MREG PF15812.5 KKK40191.1 - 0.55 10.5 5.4 2.4 8.4 1.3 2.1 2 0 0 2 2 2 0 Melanoregulin PAS_8 PF13188.7 KKK40192.1 - 3e-08 33.5 0.0 3.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KKK40192.1 - 1.6e-06 28.1 0.0 1.8e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KKK40192.1 - 5.4e-05 23.4 0.0 6.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KKK40192.1 - 0.0079 16.5 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 KKK40193.1 - 2.6e-24 85.9 0.0 5.8e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK40193.1 - 7e-14 51.6 0.3 2.7e-13 49.7 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 KKK40193.1 - 5.4e-06 26.2 0.0 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 KKK40193.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4795 PF16043.5 KKK40193.1 - 2.2 7.8 4.8 3.1 7.3 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Fer4 PF00037.27 KKK40195.1 - 3.3e-13 48.8 14.2 6.8e-07 28.9 3.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK40195.1 - 8.2e-12 45.5 6.0 4.3e-06 27.2 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40195.1 - 4.4e-11 42.3 13.8 6.3e-06 26.0 2.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK40195.1 - 5.6e-10 40.0 7.2 4.1e-05 24.4 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK40195.1 - 6e-09 35.9 18.7 8.1e-06 25.9 11.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK40195.1 - 8.7e-09 35.4 9.2 1.4e-08 34.8 9.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40195.1 - 1.2e-08 34.5 11.8 0.00013 21.8 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK40195.1 - 8.2e-08 32.3 10.0 1e-07 31.9 10.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK40195.1 - 1.9e-07 31.4 5.6 0.0035 17.8 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK40195.1 - 2.1e-07 31.4 6.9 0.003 18.1 0.7 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK40195.1 - 1.8e-05 24.9 11.0 0.014 15.8 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KKK40195.1 - 0.013 16.4 17.3 0.39 11.8 4.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.6 KKK40195.1 - 0.12 12.5 4.9 0.92 9.7 4.9 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK40195.1 - 0.16 12.7 12.9 0.88 10.3 1.7 2.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 KKK40195.1 - 0.17 12.8 12.0 0.35 11.8 2.0 2.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK40195.1 - 0.24 12.0 13.8 1 9.9 2.9 2.7 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I SNAP PF14938.6 KKK40197.1 - 0.0025 17.3 3.7 0.0038 16.7 3.7 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KKK40197.1 - 0.0027 17.7 1.5 0.089 12.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK40197.1 - 0.029 14.2 0.1 0.029 14.2 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Transglut_C PF00927.22 KKK40197.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Peptidase_M24 PF00557.24 KKK40198.1 - 1.1e-39 136.3 0.0 1.6e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KKK40198.1 - 1.1e-05 26.1 0.0 2.9e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF4866 PF16160.5 KKK40198.1 - 0.039 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) Glycos_trans_3N PF02885.17 KKK40199.1 - 3.3e-12 46.0 0.0 6.4e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain AMP-binding PF00501.28 KKK40207.1 - 1.2e-92 310.8 0.0 1.4e-92 310.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK40207.1 - 1.4e-15 58.0 0.0 2.6e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACP_syn_III_C PF08541.10 KKK40208.1 - 1.5e-14 53.9 0.1 8e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KKK40208.1 - 1.3e-10 40.9 0.0 2.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KKK40208.1 - 0.16 11.3 0.0 0.34 10.2 0.0 1.7 1 1 0 1 1 1 0 Thiolase, N-terminal domain Abhydrolase_1 PF00561.20 KKK40209.1 - 8.7e-29 100.9 0.0 5.3e-21 75.4 0.0 2.0 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK40209.1 - 1.1e-21 77.3 0.0 1.2e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK40209.1 - 4.1e-18 66.8 0.0 5.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KKK40209.1 - 0.00011 21.9 0.0 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Abhydrolase_4 PF08386.10 KKK40209.1 - 0.00021 21.3 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KKK40209.1 - 0.0008 18.9 0.0 0.079 12.4 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KKK40209.1 - 0.0029 17.4 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK40209.1 - 0.0045 16.8 0.0 0.045 13.5 0.0 2.3 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KKK40209.1 - 0.0059 16.4 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.18 KKK40209.1 - 0.049 13.2 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.12 KKK40209.1 - 0.051 12.2 0.0 5.1 5.7 0.0 3.0 3 1 0 3 3 3 0 Acetyl xylan esterase (AXE1) Ser_hydrolase PF06821.13 KKK40209.1 - 0.071 13.0 0.0 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Lipase_3 PF01764.25 KKK40209.1 - 0.099 12.5 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 KKK40209.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 KKK40209.1 - 0.21 11.6 0.0 0.53 10.3 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain AAA PF00004.29 KKK40215.1 - 4.5e-45 153.3 0.4 4.2e-44 150.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKK40215.1 - 6e-15 54.9 0.0 1.9e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKK40215.1 - 3e-13 49.4 0.7 5.9e-13 48.4 0.7 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK40215.1 - 1.4e-07 32.1 1.6 0.00056 20.3 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KKK40215.1 - 1.5e-06 28.5 0.6 2.9e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK40215.1 - 3.9e-06 26.7 0.0 1.1e-05 25.2 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK40215.1 - 9.3e-06 25.7 0.2 0.00022 21.2 0.2 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 KKK40215.1 - 3.5e-05 23.4 0.0 9.2e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 KKK40215.1 - 6.2e-05 22.3 0.0 0.00015 21.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKK40215.1 - 0.00013 22.2 1.5 0.00081 19.7 0.2 2.5 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 KKK40215.1 - 0.0013 18.5 0.0 0.0036 17.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 KKK40215.1 - 0.0018 17.5 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KKK40215.1 - 0.0047 17.5 0.3 0.011 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KKK40215.1 - 0.0065 16.7 0.7 0.035 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KKK40215.1 - 0.0078 15.6 0.1 0.019 14.4 0.0 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK40215.1 - 0.0091 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KKK40215.1 - 0.01 15.8 0.3 0.47 10.3 0.0 2.3 1 1 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KKK40215.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KKK40215.1 - 0.015 15.1 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KKK40215.1 - 0.017 15.1 0.2 0.36 10.7 0.1 2.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KKK40215.1 - 0.019 14.7 0.5 0.042 13.6 0.1 1.9 2 1 0 2 2 1 0 AAA domain ATPase PF06745.13 KKK40215.1 - 0.021 14.2 1.2 0.15 11.3 0.0 2.8 3 0 0 3 3 2 0 KaiC RNA_helicase PF00910.22 KKK40215.1 - 0.022 15.2 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KKK40215.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KKK40215.1 - 0.036 13.8 0.1 0.16 11.6 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KKK40215.1 - 0.04 13.2 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 KKK40215.1 - 0.044 12.9 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 KKK40215.1 - 0.052 13.3 0.7 0.46 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KKK40215.1 - 0.055 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KKK40215.1 - 0.074 12.8 0.1 0.17 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK40215.1 - 0.08 12.8 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 KKK40215.1 - 0.098 12.2 0.3 0.32 10.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KKK40215.1 - 0.11 12.8 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KKK40215.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DAP3 PF10236.9 KKK40215.1 - 0.12 11.5 0.0 5.4 6.1 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KKK40215.1 - 0.14 12.6 0.1 0.48 10.9 0.0 1.9 2 0 0 2 2 1 0 ABC transporter CENP-Q PF13094.6 KKK40215.1 - 1.5 9.0 8.9 4.9 7.3 6.8 2.4 3 0 0 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 KKK40215.1 - 4.4 7.8 9.6 1.4 9.5 6.3 1.8 2 0 0 2 2 1 0 Apg6 coiled-coil region TGT_C2 PF14810.6 KKK40216.1 - 2.4e-19 69.2 0.0 4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase PUA PF01472.20 KKK40216.1 - 2.9e-12 46.4 0.1 3.9e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KKK40216.1 - 5e-07 29.9 0.2 3.1e-06 27.4 0.2 2.2 1 1 1 2 2 2 1 UPF0113 PUA domain GIT_SHD PF08518.11 KKK40216.1 - 0.076 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT NAC PF01849.18 KKK40217.1 - 8.6e-11 41.7 0.7 1.7e-10 40.7 0.7 1.5 1 0 0 1 1 1 1 NAC domain DMA PF03474.14 KKK40217.1 - 0.0025 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif NRDD PF13597.6 KKK40219.1 - 3.3e-122 409.1 0.2 4e-122 408.8 0.2 1.0 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase HypA PF01155.19 KKK40219.1 - 0.0056 16.7 0.2 0.038 14.0 0.3 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KKK40219.1 - 0.043 13.5 0.6 0.094 12.4 0.6 1.5 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 tRNA_anti_2 PF13742.6 KKK40219.1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DZR PF12773.7 KKK40219.1 - 0.22 11.6 2.1 0.44 10.6 2.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 KKK40219.1 - 0.33 11.0 4.3 1 9.5 4.3 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger MazG PF03819.17 KKK40220.1 - 7.5e-11 42.1 0.0 9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Transposase_31 PF04754.12 KKK40220.1 - 0.015 14.9 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Putative transposase, YhgA-like DUF2299 PF10061.9 KKK40220.1 - 0.032 14.0 0.1 0.036 13.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) Cep57_MT_bd PF06657.13 KKK40220.1 - 0.048 14.1 0.1 1.8 9.1 0.1 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pyridoxal_deC PF00282.19 KKK40221.1 - 2.2e-33 115.5 0.0 5.7e-33 114.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKK40221.1 - 4.2e-13 49.0 0.0 1.4e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK40221.1 - 2.7e-08 33.4 0.0 7.7e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KKK40221.1 - 8.7e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KKK40221.1 - 0.00023 20.5 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DZR PF12773.7 KKK40222.1 - 1.2e-06 28.4 4.5 0.018 15.1 0.2 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK40222.1 - 0.00032 21.4 9.4 0.14 12.9 2.1 2.6 2 1 0 2 2 2 2 zinc-ribbon family zf-C4H2 PF10146.9 KKK40222.1 - 0.0009 19.6 2.7 0.0016 18.8 2.7 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein zf-ribbon_3 PF13248.6 KKK40222.1 - 0.0024 17.2 14.4 0.0097 15.3 1.3 3.4 3 0 0 3 3 3 2 zinc-ribbon domain Rubredoxin_2 PF18073.1 KKK40222.1 - 0.0079 15.9 5.7 0.0079 15.9 5.7 2.3 2 0 0 2 2 2 1 Rubredoxin metal binding domain Zn_ribbon_17 PF17120.5 KKK40222.1 - 0.0087 15.7 6.4 0.048 13.3 0.6 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KKK40222.1 - 0.016 15.1 8.4 0.18 11.7 2.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 KKK40222.1 - 0.21 11.6 6.4 0.63 10.1 0.5 2.5 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_1 PF14446.6 KKK40222.1 - 0.29 11.1 7.0 3.3 7.7 0.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-IS66 PF13005.7 KKK40222.1 - 0.37 11.2 6.0 3.2 8.2 0.0 4.3 5 0 0 5 5 5 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_2 PF13240.6 KKK40222.1 - 0.75 9.6 14.6 3.1 7.6 1.9 3.2 2 2 0 2 2 2 0 zinc-ribbon domain zf-RING_10 PF16685.5 KKK40222.1 - 0.86 9.8 5.4 0.54 10.4 0.4 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 KKK40222.1 - 1 9.0 8.4 5.3 6.7 0.5 2.5 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 Rhodanese_C PF12368.8 KKK40222.1 - 2.3 8.6 6.0 9.8 6.6 1.4 2.8 2 1 0 2 2 2 0 Rhodanase C-terminal Zn-ribbon_8 PF09723.10 KKK40222.1 - 2.8 8.1 10.1 15 5.8 0.0 3.6 3 1 0 3 3 3 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 KKK40222.1 - 4.1 7.5 5.3 28 4.8 0.2 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Ras PF00071.22 KKK40223.1 - 7.7e-52 175.2 0.0 1.3e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40223.1 - 8.8e-32 109.8 0.0 2.4e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40223.1 - 5.8e-08 32.4 0.0 5.8e-08 32.4 0.0 1.9 2 1 0 2 2 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KKK40223.1 - 0.0012 18.6 0.0 0.0012 18.6 0.0 3.1 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein zinc_ribbon_15 PF17032.5 KKK40223.1 - 0.0013 19.5 0.3 0.0058 17.4 0.3 2.1 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 KKK40223.1 - 0.004 17.2 0.9 0.0068 16.4 0.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK40223.1 - 0.011 15.5 2.4 0.021 14.5 2.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK40223.1 - 0.015 14.7 2.0 0.027 13.9 2.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain GTP_EFTU PF00009.27 KKK40223.1 - 0.093 12.3 0.0 0.093 12.3 0.0 2.8 2 1 0 2 2 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK40223.1 - 0.1 12.5 4.9 0.48 10.3 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase Gtr1_RagA PF04670.12 KKK40223.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.1 2 1 0 2 2 1 0 Gtr1/RagA G protein conserved region A2L_zn_ribbon PF08792.10 KKK40223.1 - 0.54 10.1 5.4 1.3 8.9 5.4 1.6 1 1 0 1 1 1 0 A2L zinc ribbon domain NPR3 PF03666.13 KKK40223.1 - 0.59 8.9 18.8 0.86 8.3 18.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HSP70 PF00012.20 KKK40223.1 - 0.79 7.8 18.8 1.1 7.3 18.8 1.1 1 0 0 1 1 1 0 Hsp70 protein Vfa1 PF08432.10 KKK40223.1 - 0.94 9.8 28.3 1.9 8.8 28.3 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2828 PF11443.8 KKK40223.1 - 4.9 5.1 14.9 7 4.6 14.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2151 PF10221.9 KKK40223.1 - 5.3 5.5 18.6 8.2 4.9 18.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Mitofilin PF09731.9 KKK40223.1 - 5.4 5.7 32.0 7.9 5.2 32.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MCM_bind PF09739.9 KKK40223.1 - 6.4 5.1 15.6 9.2 4.6 15.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_11 PF13086.6 KKK40223.1 - 7 6.4 19.4 12 5.5 19.4 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_4 PF01063.19 KKK40225.1 - 1.6e-37 129.5 0.0 1.9e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Ras PF00071.22 KKK40226.1 - 1.5e-32 112.5 0.6 1.7e-32 112.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40226.1 - 1.3e-23 83.4 0.1 1.8e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40226.1 - 7e-08 32.1 0.3 7.7e-08 32.0 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 KKK40226.1 - 0.00046 20.0 0.2 0.4 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Gtr1_RagA PF04670.12 KKK40226.1 - 0.002 17.5 0.2 0.0033 16.8 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK40226.1 - 0.0022 18.1 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KKK40226.1 - 0.0041 16.9 1.0 0.043 13.6 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 KKK40226.1 - 0.0055 16.8 0.1 0.022 14.8 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 KKK40226.1 - 0.023 15.1 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KKK40226.1 - 0.029 13.8 0.1 0.071 12.5 0.0 1.6 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit DAP3 PF10236.9 KKK40226.1 - 0.03 13.5 0.6 0.17 11.0 0.0 2.2 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 RsgA_GTPase PF03193.16 KKK40226.1 - 0.05 13.5 0.4 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KKK40226.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KKK40226.1 - 0.076 12.9 0.0 2.9 7.8 0.0 2.2 2 1 0 2 2 2 0 NTPase Peptidase_M20 PF01546.28 KKK40227.1 - 7.7e-16 58.4 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK40227.1 - 1.8e-08 34.2 0.0 4.5e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Vta1 PF04652.16 KKK40227.1 - 0.079 12.9 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Vta1 like RVT_N PF13655.6 KKK40228.1 - 2.1e-05 24.7 0.5 3.2e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 N-terminal domain of reverse transcriptase MAD PF05557.13 KKK40228.1 - 0.041 12.3 0.1 0.041 12.3 0.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Sacchrp_dh_NADP PF03435.18 KKK40229.1 - 1.9e-10 41.1 0.0 3.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KKK40229.1 - 2.4e-08 34.1 0.0 4.5e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK40229.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fer4 PF00037.27 KKK40230.1 - 1.8e-13 49.7 14.4 5.9e-07 29.0 4.6 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK40230.1 - 1.4e-10 41.6 24.5 1.3e-07 32.1 13.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40230.1 - 2.7e-10 39.9 14.7 5.6e-06 26.2 1.4 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK40230.1 - 1.6e-09 37.8 9.6 3.5e-09 36.7 9.8 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK40230.1 - 3.5e-09 36.6 25.2 6.5e-07 29.4 13.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK40230.1 - 6.8e-09 35.7 11.7 0.00013 22.0 1.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40230.1 - 1.3e-08 34.4 10.6 0.00023 21.1 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK40230.1 - 1.7e-08 35.2 9.7 0.00046 21.1 0.9 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK40230.1 - 3.4e-07 30.6 9.1 0.00075 19.9 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK40230.1 - 3.7e-06 27.7 7.8 0.017 16.0 1.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK40230.1 - 6.2e-06 26.7 6.5 0.021 15.4 1.0 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK40230.1 - 1.7e-05 25.4 22.0 0.0016 19.2 6.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 KKK40230.1 - 2.2e-05 25.1 7.3 0.0016 19.1 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_4 PF12800.7 KKK40230.1 - 5.5e-05 23.4 16.2 0.0011 19.4 4.0 2.2 1 1 1 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 KKK40230.1 - 0.0023 18.4 12.6 0.15 12.6 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KKK40230.1 - 0.26 11.5 13.3 5.2 7.3 13.3 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Antibiotic_NAT PF02522.14 KKK40231.1 - 1.7e-75 253.7 0.0 2e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase Hexapep PF00132.24 KKK40232.1 - 3.5e-19 67.7 14.3 2.8e-07 30.0 2.0 4.2 2 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK40232.1 - 0.0058 16.3 11.0 0.28 11.0 1.3 4.5 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase HAS-barrel PF09378.10 KKK40232.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 HAS barrel domain zinc_ribbon_2 PF13240.6 KKK40233.1 - 4.2e-05 23.1 0.5 6.9e-05 22.4 0.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK40233.1 - 0.00016 21.0 2.5 0.00029 20.1 2.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK40233.1 - 0.0088 16.0 0.4 0.013 15.5 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK40233.1 - 0.01 16.6 0.9 0.017 15.9 0.9 1.3 1 0 0 1 1 1 0 zinc-ribbon family E7 PF00527.18 KKK40233.1 - 0.085 13.1 0.2 0.15 12.2 0.2 1.3 1 0 0 1 1 1 0 E7 protein, Early protein S6PP_C PF08472.10 KKK40233.1 - 0.089 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal UPF0547 PF10571.9 KKK40233.1 - 0.34 11.0 2.1 0.65 10.1 2.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.12 KKK40233.1 - 0.37 10.3 3.4 1.1 8.8 3.4 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding DUF1610 PF07754.11 KKK40233.1 - 0.68 10.0 9.8 3.1 7.8 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) YhfH PF14149.6 KKK40233.1 - 1.7 8.7 6.6 0.76 9.8 1.1 2.5 2 1 0 2 2 2 0 YhfH-like protein MaoC_dehydratas PF01575.19 KKK40234.1 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK40234.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase DUF3221 PF11518.8 KKK40237.1 - 0.052 13.9 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) ADK PF00406.22 KKK40238.1 - 1.9e-48 164.4 0.0 2.2e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KKK40238.1 - 1.7e-23 83.6 0.1 2.5e-22 79.8 0.0 2.0 1 1 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KKK40238.1 - 9.2e-12 44.7 0.5 1.6e-11 44.0 0.5 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KKK40238.1 - 2e-05 25.1 0.0 4.1e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KKK40238.1 - 0.0055 16.9 0.0 0.012 15.8 0.0 1.6 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KKK40238.1 - 0.0082 15.9 1.4 0.07 12.8 0.2 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KKK40238.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HypA PF01155.19 KKK40238.1 - 0.029 14.4 0.2 0.12 12.4 0.2 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RuvB_N PF05496.12 KKK40238.1 - 0.056 13.2 0.1 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain zf_UBZ PF18439.1 KKK40238.1 - 0.088 12.4 1.8 2.9 7.5 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PSI_PsaF PF02507.15 KKK40238.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III zinc_ribbon_4 PF13717.6 KKK40238.1 - 0.5 10.3 2.4 1.5 8.8 2.4 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF1451 PF07295.11 KKK40238.1 - 2.2 8.3 4.2 25 4.9 1.4 2.8 1 1 1 2 2 2 0 Zinc-ribbon containing domain DHquinase_I PF01487.15 KKK40239.1 - 3.3e-46 158.4 0.1 1e-45 156.8 0.1 1.6 1 1 0 1 1 1 1 Type I 3-dehydroquinase Bac_luciferase PF00296.20 KKK40246.1 - 7.6e-54 183.3 0.0 1.2e-52 179.3 0.0 1.8 1 1 1 2 2 2 1 Luciferase-like monooxygenase BLI1 PF17324.2 KKK40246.1 - 0.0058 17.3 0.5 0.068 13.8 0.1 2.7 3 0 0 3 3 3 1 BLOC-1 interactor 1 NucS PF01939.16 KKK40247.1 - 1.8e-07 30.7 0.2 2.1e-07 30.5 0.2 1.1 1 0 0 1 1 1 1 Endonuclease NucS PDDEXK_9 PF08011.11 KKK40247.1 - 0.0019 18.1 0.2 0.003 17.5 0.2 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily YhcG_C PF06250.11 KKK40247.1 - 0.026 14.3 0.2 0.03 14.1 0.2 1.4 1 0 0 1 1 1 0 YhcG PDDEXK nuclease domain AAA_31 PF13614.6 KKK40249.1 - 4e-46 157.2 0.6 8e-46 156.2 0.6 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KKK40249.1 - 1.4e-20 73.6 0.3 1e-19 70.8 0.3 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 KKK40249.1 - 2.5e-12 46.8 0.0 3.3e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 KKK40249.1 - 5.4e-11 42.2 0.1 1.2e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KKK40249.1 - 1.9e-09 37.4 0.1 2.3e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KKK40249.1 - 3.1e-09 36.7 0.0 6.4e-06 25.8 0.0 2.3 1 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 KKK40249.1 - 1.5e-07 31.0 0.1 0.0029 16.9 0.0 2.2 1 1 1 2 2 2 2 ATPase MipZ CLP1_P PF16575.5 KKK40249.1 - 0.00025 20.9 0.2 0.0019 18.0 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 KKK40249.1 - 0.00034 20.0 0.1 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 VirC1 protein SRP54 PF00448.22 KKK40249.1 - 0.0012 18.5 0.2 0.011 15.3 0.0 2.6 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KKK40249.1 - 0.0025 17.6 0.1 0.27 11.0 0.0 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KKK40249.1 - 0.18 10.8 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 KKK40250.1 - 1.6e-17 64.3 0.6 5.3e-17 62.7 0.6 1.8 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 KKK40250.1 - 2.6e-08 34.2 0.1 0.0059 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.7 KKK40250.1 - 1.1e-05 24.5 0.6 2.7e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 AAA-like domain ResIII PF04851.15 KKK40250.1 - 3.8e-05 23.7 0.1 0.0031 17.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KKK40250.1 - 5.4e-05 22.6 0.1 0.1 11.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) T4SS-DNA_transf PF02534.14 KKK40250.1 - 9.6e-05 21.4 0.1 0.34 9.7 0.0 2.2 2 0 0 2 2 2 2 Type IV secretory system Conjugative DNA transfer TrwB_AAD_bind PF10412.9 KKK40250.1 - 0.00025 20.1 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 KKK40250.1 - 0.00039 20.4 0.1 0.0014 18.6 0.1 2.0 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ATPase PF06745.13 KKK40250.1 - 0.002 17.5 0.9 1.2 8.4 0.1 2.5 2 0 0 2 2 2 2 KaiC ABC_tran PF00005.27 KKK40250.1 - 0.0022 18.5 0.6 0.01 16.4 0.6 2.1 1 1 0 1 1 1 1 ABC transporter AAA PF00004.29 KKK40250.1 - 0.0038 17.6 0.3 1.8 9.0 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KKK40250.1 - 0.0096 15.5 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Zot PF05707.12 KKK40250.1 - 0.012 15.3 1.0 0.018 14.7 0.1 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SWI2_SNF2 PF18766.1 KKK40250.1 - 0.022 14.4 0.3 0.63 9.7 0.0 2.6 2 0 0 2 2 2 0 SWI2/SNF2 ATPase NB-ARC PF00931.22 KKK40250.1 - 0.022 13.9 0.1 0.17 11.0 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 KKK40250.1 - 0.049 13.4 0.3 2.4 7.8 0.0 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.29 KKK40250.1 - 0.086 12.6 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 KKK40250.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NurA PF09376.10 KKK40251.1 - 0.00011 21.9 0.1 0.00024 20.9 0.1 1.5 1 1 0 1 1 1 1 NurA domain DUF2443 PF10398.9 KKK40251.1 - 0.034 14.2 0.4 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) MULE PF10551.9 KKK40255.1 - 0.00037 20.9 0.1 0.00086 19.7 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 KKK40255.1 - 0.038 12.9 0.1 0.038 12.9 0.1 2.5 3 1 0 3 3 3 0 Transposase, Mutator family DUF659 PF04937.15 KKK40255.1 - 0.041 13.7 0.3 0.33 10.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) Rx_N PF18052.1 KKK40255.1 - 3.4 8.0 6.1 2.4 8.5 3.3 2.2 2 0 0 2 2 2 0 Rx N-terminal domain Zn_dep_PLPC PF00882.18 KKK40256.1 - 0.0056 16.7 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 Zinc dependent phospholipase C Zn_Tnp_IS91 PF14319.6 KKK40257.1 - 0.00047 20.1 0.1 0.00056 19.9 0.1 1.2 1 0 0 1 1 1 1 Transposase zinc-binding domain YhfH PF14149.6 KKK40257.1 - 0.00099 19.0 3.1 0.015 15.2 0.2 2.2 2 0 0 2 2 2 1 YhfH-like protein DZR PF12773.7 KKK40257.1 - 0.0013 18.8 0.6 0.0019 18.2 0.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KKK40257.1 - 0.0028 17.6 1.8 0.81 9.7 0.3 2.2 1 1 1 2 2 2 2 Transposase zinc-ribbon domain HypA PF01155.19 KKK40257.1 - 0.0049 16.9 0.1 0.0061 16.6 0.1 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KKK40257.1 - 0.0066 15.8 3.8 0.37 10.2 0.3 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK40257.1 - 0.011 15.4 7.4 0.2 11.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 KKK40257.1 - 0.021 14.7 2.2 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 KKK40257.1 - 0.031 14.4 2.1 0.058 13.5 2.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 KKK40257.1 - 0.036 14.8 0.6 0.14 12.9 1.0 1.7 1 1 1 2 2 2 0 zinc-ribbon family NRDD PF13597.6 KKK40257.1 - 0.048 12.4 0.2 0.053 12.3 0.2 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Ribosomal_L40e PF01020.17 KKK40257.1 - 0.055 13.4 1.0 0.088 12.7 1.0 1.3 1 0 0 1 1 1 0 Ribosomal L40e family DUF1451 PF07295.11 KKK40257.1 - 0.056 13.5 0.6 0.067 13.2 0.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-IS66 PF13005.7 KKK40257.1 - 0.062 13.7 1.2 7.7 7.0 0.1 2.2 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-NADH-PPase PF09297.11 KKK40257.1 - 0.12 12.1 1.8 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain A2L_zn_ribbon PF08792.10 KKK40257.1 - 0.67 9.7 6.6 10 6.0 6.6 2.1 1 1 0 1 1 1 0 A2L zinc ribbon domain ADK_lid PF05191.14 KKK40257.1 - 1.2 9.2 3.8 2.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-TFIIB PF13453.6 KKK40257.1 - 1.8 7.9 5.3 26 4.3 5.3 2.5 1 1 0 1 1 1 0 Transcription factor zinc-finger PhnA_Zn_Ribbon PF08274.12 KKK40257.1 - 2.5 8.1 6.6 9.1 6.3 0.4 2.5 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf_C2H2_10 PF18414.1 KKK40257.1 - 4.2 7.0 5.4 3.2 7.4 0.5 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger zf_UBZ PF18439.1 KKK40257.1 - 5.9 6.6 7.2 3.5 7.3 1.0 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger HD PF01966.22 KKK40259.1 - 4.9e-09 36.4 0.4 1.6e-08 34.8 0.2 2.1 2 0 0 2 2 2 1 HD domain HD PF01966.22 KKK40260.1 - 0.0065 16.7 0.0 5.6 7.2 0.0 2.5 1 1 1 2 2 2 2 HD domain NUC194 PF08163.12 KKK40261.1 - 0.013 14.4 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 NUC194 domain Mt_ATP_synt PF15704.5 KKK40261.1 - 0.2 11.5 1.3 0.72 9.7 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial ATP synthase subunit LRR_8 PF13855.6 KKK40262.1 - 1.7e-17 62.9 20.4 2.9e-08 33.4 2.9 5.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 KKK40262.1 - 1.1e-11 44.8 18.5 7.9e-06 26.1 0.5 5.8 2 1 6 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK40262.1 - 0.0008 19.6 13.8 4.8 8.1 0.2 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat SpoU_sub_bind PF08032.12 KKK40262.1 - 0.0073 16.6 1.3 0.045 14.0 0.2 2.4 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Zmiz1_N PF18028.1 KKK40262.1 - 0.012 15.9 0.0 0.041 14.2 0.0 1.8 1 1 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain DUF1543 PF07566.12 KKK40262.1 - 0.016 14.9 0.8 0.75 9.6 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) LRR_6 PF13516.6 KKK40262.1 - 0.036 14.1 7.9 6.4 7.1 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Lig_C PF18330.1 KKK40262.1 - 0.19 11.8 0.9 38 4.3 0.1 3.2 3 1 1 4 4 4 0 Ligase Pab1020 C-terminal region DUF4252 PF14060.6 KKK40262.1 - 1.5 8.7 11.5 0.76 9.7 1.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4252) DUF5001 PF16392.5 KKK40266.1 - 0.019 14.9 4.0 0.32 10.9 0.4 3.4 2 1 0 3 3 3 0 Ig-like domain Peptidase_M20 PF01546.28 KKK40267.1 - 5.9e-36 124.1 0.0 1.1e-35 123.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK40267.1 - 2.1e-21 75.9 0.0 6.5e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK40267.1 - 0.00063 19.5 0.0 0.0016 18.2 0.0 1.7 2 1 1 3 3 3 1 Peptidase family M28 partial_CstF PF15861.5 KKK40267.1 - 0.023 14.5 0.5 0.069 12.9 0.5 1.8 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain DUF2870 PF11069.8 KKK40267.1 - 0.15 12.5 0.2 0.37 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) VWA_2 PF13519.6 KKK40268.1 - 6.5e-13 49.3 0.1 1.2e-12 48.4 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKK40268.1 - 7e-11 42.7 0.2 1e-10 42.2 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KKK40268.1 - 1.7e-06 28.0 0.1 2.7e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like PHD PF00628.29 KKK40268.1 - 7.3e-05 22.6 15.3 0.0019 18.0 6.0 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 KKK40268.1 - 8.5e-05 22.4 10.7 0.0072 16.2 1.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KKK40268.1 - 0.0022 18.3 13.9 0.12 12.7 1.6 3.2 3 0 0 3 3 3 2 C1 domain RINGv PF12906.7 KKK40268.1 - 0.069 13.3 4.3 0.16 12.1 4.3 1.7 1 0 0 1 1 1 0 RING-variant domain Cytochrome_CBB3 PF13442.6 KKK40268.1 - 0.1 12.9 1.5 1.7 9.0 0.2 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III zf-HC5HC2H PF13771.6 KKK40268.1 - 0.27 11.5 12.4 0.48 10.7 0.4 2.7 2 1 0 2 2 2 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 KKK40268.1 - 0.34 10.6 13.1 0.39 10.4 5.3 2.8 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KKK40268.1 - 1 9.3 17.6 0.05 13.5 1.8 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 KKK40268.1 - 1.3 9.0 15.1 4.5 7.2 5.9 2.7 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon zf-RING_2 PF13639.6 KKK40268.1 - 2.2 8.7 16.4 0.22 11.9 7.2 2.5 2 1 0 2 2 2 0 Ring finger domain Zn_Tnp_IS1595 PF12760.7 KKK40268.1 - 7.8 6.6 13.9 4.6 7.3 0.1 3.6 3 1 1 4 4 3 0 Transposase zinc-ribbon domain TMEM43 PF07787.12 KKK40270.1 - 1.3 8.3 11.2 0.23 10.8 2.4 2.1 2 0 0 2 2 2 0 Transmembrane protein 43 DUF1943 PF09172.11 KKK40271.1 - 0.053 12.8 0.2 0.088 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Erf4 PF10256.9 KKK40271.1 - 0.32 11.1 5.2 8.3 6.6 2.6 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family 3HCDH PF00725.22 KKK40272.1 - 6e-19 68.5 0.1 7.4e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF1657 PF07870.11 KKK40272.1 - 0.0078 16.1 0.6 0.012 15.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1657) UvrD_C PF13361.6 KKK40276.1 - 5.9e-22 78.5 0.3 9.2e-22 77.9 0.0 1.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 KKK40276.1 - 1.2e-12 47.4 0.0 5.4e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 KKK40276.1 - 0.00021 20.9 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKK40276.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF998 PF06197.13 KKK40277.1 - 2.3e-09 37.1 7.4 1.2e-05 25.0 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF998) Frag1 PF10277.9 KKK40277.1 - 0.0016 18.1 5.0 0.0042 16.7 5.0 1.8 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family Sdh_cyt PF01127.22 KKK40277.1 - 0.0062 16.6 0.1 0.0062 16.6 0.1 2.4 3 0 0 3 3 3 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit VMA21 PF09446.10 KKK40277.1 - 0.068 13.3 1.3 0.068 13.3 1.3 2.2 2 0 0 2 2 2 0 VMA21-like domain Lactamase_B_3 PF13483.6 KKK40278.1 - 4.8e-14 52.6 0.0 8e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KKK40278.1 - 9.8e-14 51.3 0.0 4.8e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK40278.1 - 2.8e-07 30.8 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KKK40278.1 - 0.094 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain DUF166 PF02593.14 KKK40279.1 - 5.4e-18 65.4 0.1 6.5e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function RNase_T PF00929.24 KKK40281.1 - 5.1e-10 40.1 0.0 7.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KKK40281.1 - 0.0017 18.3 0.6 0.03 14.3 0.6 2.2 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like RNase_H_2 PF13482.6 KKK40281.1 - 0.017 15.1 0.1 0.17 11.9 0.1 2.1 1 1 0 1 1 1 0 RNase_H superfamily Zn_Tnp_IS1595 PF12760.7 KKK40282.1 - 0.0015 18.5 0.9 0.0024 17.8 0.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain HypA PF01155.19 KKK40282.1 - 0.0017 18.4 1.2 0.002 18.1 1.2 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KKK40282.1 - 0.0017 18.3 2.2 0.0024 17.8 2.2 1.2 1 0 0 1 1 1 1 zinc-ribbons Zn-ribbon_8 PF09723.10 KKK40282.1 - 0.0044 17.1 2.9 1.1 9.5 2.0 2.4 2 0 0 2 2 2 2 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KKK40282.1 - 0.0063 16.4 1.2 1.8 8.5 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain Sgf11 PF08209.11 KKK40282.1 - 0.0069 15.9 2.5 0.51 10.0 0.1 2.3 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) FYVE PF01363.21 KKK40282.1 - 0.0094 16.1 1.4 0.012 15.8 1.1 1.4 1 1 0 1 1 1 1 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 KKK40282.1 - 0.02 14.8 0.6 0.041 13.8 0.6 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 KKK40282.1 - 0.021 14.2 1.0 0.14 11.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 KKK40282.1 - 0.035 14.0 4.0 0.035 14.0 4.0 1.9 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Rubredoxin_2 PF18073.1 KKK40282.1 - 0.043 13.5 2.5 2.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF3797 PF12677.7 KKK40282.1 - 0.053 13.4 1.0 0.053 13.4 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) TackOD1 PF18551.1 KKK40282.1 - 0.053 13.2 4.7 0.19 11.4 4.5 1.8 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 DUF2614 PF11023.8 KKK40282.1 - 0.058 13.5 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain DZR PF12773.7 KKK40282.1 - 0.075 13.1 2.3 0.11 12.5 2.1 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 KKK40282.1 - 0.22 11.2 3.7 4.3 7.0 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 KKK40282.1 - 0.8 10.2 6.2 9.7 6.8 0.2 2.4 2 1 0 2 2 2 0 Zinc-finger double domain Evr1_Alr PF04777.13 KKK40282.1 - 0.88 10.1 3.5 5.7 7.5 0.2 2.0 1 1 1 2 2 2 0 Erv1 / Alr family zinc_ribbon_5 PF13719.6 KKK40282.1 - 4.3 7.2 7.2 2 8.2 1.7 2.7 2 1 0 2 2 2 0 zinc-ribbon domain FAD_binding_4 PF01565.23 KKK40286.1 - 7.7e-33 113.2 0.0 1.1e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fer4_2 PF12797.7 KKK40287.1 - 0.00015 21.7 2.0 0.00021 21.2 2.0 1.3 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4 PF00037.27 KKK40287.1 - 0.00029 20.5 1.8 0.00047 19.8 1.8 1.3 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_7 PF12838.7 KKK40287.1 - 0.00087 19.8 0.3 0.00089 19.8 0.3 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK40287.1 - 0.0011 19.1 0.1 0.0011 19.1 0.1 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK40287.1 - 0.0031 17.9 2.2 0.0047 17.3 2.2 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK40287.1 - 0.0032 17.6 0.9 0.0045 17.1 0.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK40287.1 - 0.0074 16.7 3.4 0.011 16.2 3.4 1.2 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_17 PF13534.6 KKK40287.1 - 0.008 16.7 3.0 0.013 16.1 3.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK40287.1 - 0.31 12.1 5.2 0.47 11.5 5.2 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain DHHC PF01529.20 KKK40293.1 - 3.9 7.6 14.6 5.8 7.0 14.6 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Hexapep PF00132.24 KKK40294.1 - 3.1e-06 26.7 1.5 0.00091 18.9 0.4 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep PF00132.24 KKK40295.1 - 3.3e-05 23.4 2.3 0.13 12.1 0.8 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK40295.1 - 7e-05 22.5 3.9 0.082 12.7 0.3 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Methyltransf_11 PF08241.12 KKK40297.1 - 1.4e-22 80.1 0.0 2.8e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK40297.1 - 3.5e-18 66.1 0.0 6.5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK40297.1 - 6.5e-17 61.7 0.0 7.9e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK40297.1 - 1.7e-12 47.2 0.0 9.3e-11 41.5 0.0 2.4 1 1 2 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KKK40297.1 - 4.5e-12 46.1 0.0 6.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK40297.1 - 1.3e-11 45.1 0.0 3.2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK40297.1 - 3e-10 39.9 0.0 4.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KKK40297.1 - 1.4e-05 24.5 0.0 2.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 KKK40297.1 - 1.5e-05 24.7 0.8 2.8e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KKK40297.1 - 1.7e-05 24.9 0.0 4.7e-05 23.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KKK40297.1 - 0.00057 19.7 0.1 0.0012 18.6 0.1 1.6 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KKK40297.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_9 PF08003.11 KKK40297.1 - 0.0032 16.4 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KKK40297.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 KKK40297.1 - 0.034 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 KKK40297.1 - 0.038 13.9 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KKK40297.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase CorA PF01544.18 KKK40297.1 - 0.09 12.1 0.0 0.46 9.8 0.0 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein UPF0020 PF01170.18 KKK40297.1 - 0.12 12.0 0.0 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_29 PF03141.16 KKK40297.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PDDEXK_1 PF12705.7 KKK40302.1 - 0.00017 21.6 0.0 0.00081 19.4 0.0 1.9 1 1 1 2 2 2 1 PD-(D/E)XK nuclease superfamily PMBR PF09373.10 KKK40302.1 - 0.048 13.8 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Pseudomurein-binding repeat Met_10 PF02475.16 KKK40303.1 - 6.8e-53 179.4 3.8 1.3e-52 178.5 3.8 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 KKK40303.1 - 7.1e-08 32.2 0.3 1.4e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KKK40303.1 - 7.1e-06 25.7 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain DNA_methylase PF00145.17 KKK40303.1 - 0.0013 18.2 2.5 0.023 14.1 0.0 2.3 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 KKK40303.1 - 0.0013 18.3 0.1 0.0033 17.0 0.1 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KKK40303.1 - 0.0037 17.1 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KKK40303.1 - 0.0039 16.9 0.1 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 KKK40303.1 - 0.019 14.6 0.0 0.072 12.7 0.0 1.9 2 1 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 KKK40303.1 - 0.078 13.7 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF371 PF04027.13 KKK40304.1 - 7.2e-46 155.5 0.1 8.6e-46 155.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) TGT PF01702.18 KKK40305.1 - 1.8e-61 208.2 0.0 2.7e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF5591 PF17884.1 KKK40305.1 - 2.6e-07 30.6 0.0 6.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) AAA_18 PF13238.6 KKK40306.1 - 4.7e-28 98.3 0.2 3.9e-27 95.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 KKK40306.1 - 3.6e-07 30.7 0.0 7.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK40306.1 - 8.6e-06 26.2 0.5 0.00017 22.0 0.1 2.5 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 KKK40306.1 - 3.6e-05 23.7 4.9 0.041 13.7 0.5 2.4 1 1 0 2 2 2 2 Deoxynucleoside kinase Rad17 PF03215.15 KKK40306.1 - 8.9e-05 22.5 0.2 0.00017 21.6 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain Thymidylate_kin PF02223.17 KKK40306.1 - 9.9e-05 22.1 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 KKK40306.1 - 0.00036 20.7 0.0 0.11 12.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 KKK40306.1 - 0.00053 20.3 0.0 0.00087 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KKK40306.1 - 0.00061 20.2 0.0 0.0023 18.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 KKK40306.1 - 0.00073 19.6 1.1 0.0019 18.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 KKK40306.1 - 0.00075 19.7 0.1 0.18 11.9 0.0 2.3 2 1 0 2 2 2 1 Shikimate kinase RuvB_N PF05496.12 KKK40306.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 KKK40306.1 - 0.0018 18.0 1.0 1.1 9.0 0.1 2.4 2 1 0 2 2 2 2 Cytidylate kinase TIP49 PF06068.13 KKK40306.1 - 0.002 17.4 0.1 0.002 17.4 0.1 1.9 2 1 1 3 3 3 1 TIP49 P-loop domain KTI12 PF08433.10 KKK40306.1 - 0.0021 17.6 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 KKK40306.1 - 0.004 16.5 0.0 0.0092 15.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 KKK40306.1 - 0.0045 17.0 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KKK40306.1 - 0.0058 16.4 0.1 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KKK40306.1 - 0.01 16.2 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KKK40306.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Hydin_ADK PF17213.3 KKK40306.1 - 0.013 15.8 0.2 0.03 14.6 0.0 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NTPase_1 PF03266.15 KKK40306.1 - 0.018 14.9 0.3 0.066 13.1 0.1 2.0 2 0 0 2 2 2 0 NTPase SRPRB PF09439.10 KKK40306.1 - 0.019 14.4 0.2 0.55 9.6 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KKK40306.1 - 0.022 14.5 0.2 0.092 12.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.18 KKK40306.1 - 0.025 14.3 0.5 0.068 12.9 0.2 1.9 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 KKK40306.1 - 0.028 14.9 1.1 0.035 14.6 1.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KKK40306.1 - 0.038 14.3 0.4 0.21 11.9 0.1 2.1 1 1 2 3 3 3 0 AAA domain ADK PF00406.22 KKK40306.1 - 0.055 13.6 0.0 0.6 10.2 0.0 2.2 2 1 0 2 2 2 0 Adenylate kinase Cytidylate_kin2 PF13189.6 KKK40306.1 - 0.069 13.3 0.3 0.44 10.7 0.3 2.4 1 1 0 1 1 1 0 Cytidylate kinase-like family CPT PF07931.12 KKK40306.1 - 0.074 12.9 0.0 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KKK40306.1 - 0.086 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 KKK40306.1 - 0.13 12.0 0.3 1.6 8.4 0.1 2.2 1 1 0 2 2 2 0 Dephospho-CoA kinase AAA_3 PF07726.11 KKK40306.1 - 0.14 12.0 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 KKK40306.1 - 0.14 11.8 0.0 0.3 10.7 0.1 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 KKK40306.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI tRNA_lig_kinase PF08303.11 KKK40306.1 - 1.5 8.9 5.8 0.91 9.6 0.3 2.3 2 1 0 2 2 2 0 tRNA ligase kinase domain TFIIB PF00382.19 KKK40311.1 - 2.4e-29 101.2 0.3 6.2e-17 61.4 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.23 KKK40311.1 - 4e-07 29.8 1.1 0.0028 17.4 0.2 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.12 KKK40311.1 - 2.7e-06 26.8 3.0 1.6e-05 24.3 3.3 2.0 1 1 1 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 KKK40311.1 - 0.00012 22.1 0.2 0.0033 17.5 0.1 2.2 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain HTH_24 PF13412.6 KKK40311.1 - 0.00044 19.7 0.7 0.052 13.1 0.0 2.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KKK40311.1 - 0.00059 20.1 0.0 0.75 10.2 0.0 2.5 2 0 0 2 2 2 2 Transcriptional regulator Sigma70_r4 PF04545.16 KKK40311.1 - 0.0058 16.1 0.2 0.54 9.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 KKK40311.1 - 0.011 15.7 0.1 0.051 13.6 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Cyclin_C PF02984.19 KKK40311.1 - 0.012 15.7 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain HTH_11 PF08279.12 KKK40311.1 - 0.028 14.4 0.5 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 HTH domain HTH_AsnC-type PF13404.6 KKK40311.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain OrfB_Zn_ribbon PF07282.11 KKK40311.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain HTH_Tnp_ISL3 PF13542.6 KKK40311.1 - 0.12 11.9 0.0 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Mga PF08280.11 KKK40311.1 - 0.16 12.0 0.7 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Hexapep PF00132.24 KKK40312.1 - 8.1e-13 47.6 6.2 1.4e-05 24.6 0.0 4.3 4 1 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK40312.1 - 0.0062 16.3 7.7 0.97 9.2 0.0 3.9 4 2 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase NIF3 PF01784.18 KKK40313.1 - 9.5e-38 130.2 0.1 1.2e-37 129.8 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Shisa PF13908.6 KKK40314.1 - 0.23 11.7 0.0 0.24 11.6 0.0 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RHH_1 PF01402.21 KKK40315.1 - 0.0016 18.3 0.1 0.077 13.0 0.0 2.4 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family Phage_min_cap2 PF06152.11 KKK40315.1 - 0.0092 14.9 0.0 0.012 14.6 0.0 1.0 1 0 0 1 1 1 1 Phage minor capsid protein 2 NLE PF08154.12 KKK40315.1 - 0.019 15.5 0.2 0.059 13.9 0.1 1.9 2 0 0 2 2 2 0 NLE (NUC135) domain TrmB PF01978.19 KKK40316.1 - 3.2e-07 30.1 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 KKK40316.1 - 0.0001 22.2 0.1 0.00014 21.7 0.1 1.2 1 0 0 1 1 1 1 MarR family PadR PF03551.14 KKK40316.1 - 0.00031 20.6 0.2 0.00075 19.4 0.2 1.6 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 KKK40316.1 - 0.0017 18.4 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 Replication-relaxation HTH_IclR PF09339.10 KKK40316.1 - 0.0018 18.1 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_11 PF08279.12 KKK40316.1 - 0.0019 18.1 0.1 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_7 PF02796.15 KKK40316.1 - 0.0026 17.8 0.1 0.0045 17.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_24 PF13412.6 KKK40316.1 - 0.0032 17.0 0.1 0.0051 16.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KKK40316.1 - 0.0076 16.3 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 KKK40316.1 - 0.011 16.2 0.0 0.013 16.0 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain Penicillinase_R PF03965.16 KKK40316.1 - 0.02 15.2 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Penicillinase repressor DUF2250 PF10007.9 KKK40316.1 - 0.033 14.3 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) TFIIE_alpha PF02002.17 KKK40316.1 - 0.033 14.0 0.1 0.038 13.8 0.1 1.1 1 0 0 1 1 1 0 TFIIE alpha subunit MarR_2 PF12802.7 KKK40316.1 - 0.041 13.8 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.12 KKK40316.1 - 0.067 12.9 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_9 PF08221.11 KKK40316.1 - 0.071 13.2 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain GntR PF00392.21 KKK40316.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 KKK40316.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 KKK40316.1 - 0.13 12.6 0.1 0.32 11.4 0.1 1.5 1 1 1 2 2 2 0 Transcriptional regulator ABC_tran PF00005.27 KKK40317.1 - 4.9e-32 111.3 0.2 3.4e-19 69.7 0.1 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK40317.1 - 2.3e-10 40.3 9.7 0.00015 21.3 0.1 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK40317.1 - 1.6e-08 34.8 8.0 0.0011 18.9 0.1 3.4 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK40317.1 - 4.7e-05 24.0 2.8 4.7e-05 24.0 2.8 2.1 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KKK40317.1 - 0.00013 21.3 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_14 PF13173.6 KKK40317.1 - 0.0016 18.4 1.3 0.1 12.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KKK40317.1 - 0.077 12.2 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 KKK40317.1 - 0.099 12.4 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK40317.1 - 0.1 12.5 0.2 0.35 10.8 0.0 1.9 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 KKK40317.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KKK40317.1 - 0.15 12.3 0.0 30 4.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain YhhN PF07947.14 KKK40320.1 - 3.6e-06 26.7 0.8 4.4e-06 26.4 0.1 1.5 2 0 0 2 2 2 1 YhhN family TMEM169 PF15052.6 KKK40320.1 - 0.39 10.9 4.4 0.45 10.6 4.4 1.2 1 0 0 1 1 1 0 TMEM169 protein family Acetyltransf_1 PF00583.25 KKK40321.1 - 0.0043 17.3 0.0 0.009 16.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK40321.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YoaP PF14268.6 KKK40321.1 - 0.015 14.8 0.0 0.039 13.4 0.0 1.8 1 0 0 1 1 1 0 YoaP-like DUF4252 PF14060.6 KKK40321.1 - 0.18 11.7 3.1 0.63 9.9 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4252) Pyrid_ox_like PF16242.5 KKK40322.1 - 5.7e-15 55.2 0.2 1.8e-14 53.5 0.1 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KKK40322.1 - 2.8e-12 46.6 0.0 7.3e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MarR PF01047.22 KKK40323.1 - 1e-12 47.8 0.2 2.1e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KKK40323.1 - 2.4e-07 30.6 0.0 4.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 KKK40323.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_34 PF13601.6 KKK40323.1 - 0.00047 20.3 0.9 0.0015 18.7 0.7 1.9 1 1 1 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 KKK40323.1 - 0.00081 19.2 0.1 0.0016 18.3 0.0 1.7 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 KKK40323.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 KKK40323.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 KKK40323.1 - 0.0026 18.1 0.2 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator TFIIE_alpha PF02002.17 KKK40323.1 - 0.004 17.0 2.2 0.0094 15.8 2.2 1.8 1 1 0 1 1 1 1 TFIIE alpha subunit HTH_27 PF13463.6 KKK40323.1 - 0.015 15.7 0.1 0.025 15.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HxlR PF01638.17 KKK40323.1 - 0.027 14.3 0.9 0.041 13.7 0.3 1.6 2 0 0 2 2 2 0 HxlR-like helix-turn-helix Cdc6_C PF09079.11 KKK40323.1 - 0.044 13.8 0.2 0.085 12.8 0.2 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain HTH_20 PF12840.7 KKK40323.1 - 0.049 13.7 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain COMM_domain PF07258.14 KKK40323.1 - 0.32 11.1 6.0 0.38 10.9 0.8 2.5 2 1 1 3 3 3 0 COMM domain Pro_CA PF00484.19 KKK40325.1 - 1.4e-22 80.7 0.0 3.8e-22 79.2 0.0 1.8 2 1 0 2 2 2 1 Carbonic anhydrase Band_7 PF01145.25 KKK40326.1 - 4e-28 98.6 0.2 4e-28 98.6 0.2 2.2 2 1 0 2 2 2 1 SPFH domain / Band 7 family Flot PF15975.5 KKK40326.1 - 0.00062 19.9 1.2 0.00062 19.9 1.2 3.6 2 1 1 3 3 3 2 Flotillin Adeno_E3_CR2 PF02439.15 KKK40326.1 - 0.042 13.6 0.5 0.076 12.8 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4528 PF15031.6 KKK40326.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) DUF1449 PF07290.11 KKK40327.1 - 5.5e-06 26.2 4.7 0.00096 18.8 4.7 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1449) Bactofilin PF04519.13 KKK40327.1 - 0.00027 21.2 0.5 0.00043 20.5 0.5 1.3 1 0 0 1 1 1 1 Polymer-forming cytoskeletal DUF1943 PF09172.11 KKK40327.1 - 0.078 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) NESP55 PF06390.12 KKK40327.1 - 1.9 8.0 7.1 16 5.0 7.1 2.0 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF1980 PF09323.10 KKK40327.1 - 7.8 6.4 7.0 17 5.2 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) zinc_ribbon_2 PF13240.6 KKK40328.1 - 1.4e-06 27.8 2.1 3.3e-06 26.6 2.1 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK40328.1 - 1.1e-05 25.3 0.5 2.4e-05 24.2 0.5 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK40328.1 - 1.7e-05 24.1 0.7 3.3e-05 23.1 0.7 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK40328.1 - 0.00032 21.4 0.3 0.00054 20.7 0.3 1.5 1 0 0 1 1 1 1 zinc-ribbon family ABC2_membrane_3 PF12698.7 KKK40328.1 - 0.0082 15.3 4.0 0.011 14.9 4.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Nudix_N_2 PF14803.6 KKK40328.1 - 0.059 13.3 4.4 2.8 7.9 0.8 2.4 2 0 0 2 2 2 0 Nudix N-terminal FtsX PF02687.21 KKK40328.1 - 0.072 13.6 7.6 0.12 12.8 7.6 1.3 1 0 0 1 1 1 0 FtsX-like permease family DUF3087 PF11286.8 KKK40328.1 - 0.085 12.3 3.5 0.12 11.8 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) DUF2207 PF09972.9 KKK40328.1 - 0.38 9.5 1.8 0.46 9.2 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FixH PF05751.11 KKK40328.1 - 0.85 9.6 0.0 0.85 9.6 0.0 1.7 2 0 0 2 2 2 0 FixH Glyco_hydro_106 PF17132.4 KKK40329.1 - 0.034 12.4 0.1 0.052 11.8 0.1 1.3 1 0 0 1 1 1 0 alpha-L-rhamnosidase rve_2 PF13333.6 KKK40329.1 - 0.036 14.3 0.7 0.11 12.7 0.0 2.2 3 0 0 3 3 3 0 Integrase core domain zf-C3HC4_3 PF13920.6 KKK40330.1 - 0.0021 17.9 2.4 0.0031 17.4 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) L27_1 PF09058.10 KKK40331.1 - 0.024 14.6 0.8 0.26 11.3 0.1 2.6 2 0 0 2 2 2 0 L27_1 Trigger_N PF05697.13 KKK40331.1 - 0.24 11.7 2.7 0.31 11.4 0.1 2.4 3 0 0 3 3 3 0 Bacterial trigger factor protein (TF) T3RM_EcoP15I_C PF18273.1 KKK40332.1 - 0.088 13.1 2.7 0.24 11.7 2.7 1.8 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain PIN PF01850.21 KKK40334.1 - 9.2e-08 32.6 0.0 1.1e-07 32.4 0.0 1.0 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 KKK40334.1 - 0.17 12.6 0.0 0.19 12.5 0.0 1.3 1 1 0 1 1 1 0 PIN domain DUF3795 PF12675.7 KKK40335.1 - 4.1e-09 36.7 20.0 1.4e-07 31.8 16.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3795) Sybindin PF04099.12 KKK40336.1 - 0.001 19.0 0.9 0.0018 18.2 0.2 1.8 2 0 0 2 2 2 1 Sybindin-like family DUF1129 PF06570.11 KKK40336.1 - 0.0012 18.4 3.6 0.0023 17.4 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) FliG_M PF14841.6 KKK40336.1 - 0.0035 17.5 0.4 0.034 14.4 0.0 2.4 3 0 0 3 3 3 1 FliG middle domain 7tm_7 PF08395.12 KKK40336.1 - 0.01 15.1 4.6 0.01 15.1 4.6 2.1 1 1 1 2 2 2 0 7tm Chemosensory receptor 3HCDH_N PF02737.18 KKK40337.1 - 6.1e-44 150.0 0.0 1.2e-43 149.1 0.0 1.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK40337.1 - 3.6e-19 69.2 0.3 6.8e-19 68.3 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK40337.1 - 0.015 15.5 0.0 0.052 13.7 0.0 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KKK40337.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2624 PF11116.8 KKK40337.1 - 0.034 15.0 0.4 5 8.1 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2624) DUF1657 PF07870.11 KKK40337.1 - 0.044 13.7 0.6 0.044 13.7 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) PIN_2 PF10130.9 KKK40337.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 PIN domain F420_oxidored PF03807.17 KKK40337.1 - 0.28 11.8 0.8 2.5 8.7 0.8 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_U32 PF01136.19 KKK40338.1 - 3.4e-78 262.0 0.2 4.4e-78 261.6 0.2 1.1 1 0 0 1 1 1 1 Peptidase family U32 GTP_EFTU_D2 PF03144.25 KKK40338.1 - 0.12 12.8 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 adh_short PF00106.25 KKK40340.1 - 1.6e-37 128.9 0.6 2.1e-37 128.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK40340.1 - 2.5e-23 82.9 0.1 3.4e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK40340.1 - 2e-09 37.6 0.2 2.7e-09 37.2 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KKK40340.1 - 0.00072 18.8 0.4 0.0022 17.2 0.3 1.8 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KKK40340.1 - 0.002 17.6 0.0 0.0065 15.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK40340.1 - 0.003 17.1 0.1 0.009 15.5 0.1 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK40340.1 - 0.016 14.8 0.2 0.038 13.5 0.0 1.7 2 1 1 3 3 3 0 NmrA-like family Phage_P2_GpE PF06528.12 KKK40340.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpE 3HCDH_N PF02737.18 KKK40340.1 - 0.11 12.3 0.0 1.4 8.8 0.0 2.1 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ras PF00071.22 KKK40341.1 - 3.6e-47 160.0 0.1 4.8e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40341.1 - 1.2e-29 102.9 0.1 2.6e-29 101.9 0.0 1.6 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40341.1 - 1.5e-15 57.1 0.2 2e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK40341.1 - 5.8e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK40341.1 - 6.2e-07 29.0 0.1 8.8e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK40341.1 - 3.4e-06 26.7 0.1 2.3e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK40341.1 - 0.00017 21.1 0.1 0.00031 20.2 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK40341.1 - 0.00021 20.6 1.9 0.0094 15.1 1.6 2.8 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 KKK40341.1 - 0.00049 20.0 0.0 0.015 15.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA PF00004.29 KKK40341.1 - 0.0027 18.1 0.4 0.073 13.5 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KKK40341.1 - 0.0048 16.4 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B TFIID-18kDa PF02269.16 KKK40341.1 - 0.0061 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit AAA_16 PF13191.6 KKK40341.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KKK40341.1 - 0.019 14.7 0.1 0.033 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK40341.1 - 0.035 14.2 0.2 0.27 11.3 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK40341.1 - 0.042 14.4 0.1 0.18 12.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.23 KKK40341.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.11 KKK40341.1 - 0.065 13.3 0.7 1.3 9.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1931) RuvB_N PF05496.12 KKK40341.1 - 0.083 12.6 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KKK40341.1 - 0.084 13.1 0.0 0.31 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 KKK40341.1 - 0.12 11.8 0.2 0.25 10.7 0.0 1.6 2 0 0 2 2 1 0 Bacterial TniB protein Saccharop_dh_N PF04455.12 KKK40341.1 - 0.17 12.3 1.7 4.1 7.9 0.0 2.9 3 0 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region AAR2 PF05282.11 KKK40342.1 - 2e-23 83.4 0.6 4.9e-11 42.6 0.0 2.0 1 1 1 2 2 2 2 AAR2 protein Hpr_kinase_N PF02603.16 KKK40342.1 - 0.13 12.3 0.1 0.69 9.9 0.1 2.0 1 1 1 2 2 2 0 HPr Serine kinase N terminus Cas_NE0113 PF09623.10 KKK40343.1 - 0.042 13.5 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) HTH_34 PF13601.6 KKK40343.1 - 0.073 13.3 0.4 18 5.6 0.0 2.8 3 0 0 3 3 3 0 Winged helix DNA-binding domain FAD-oxidase_C PF02913.19 KKK40344.1 - 7.2e-34 117.5 0.0 9.9e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKK40344.1 - 2.2e-21 76.0 0.0 2.4e-09 37.1 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain AFOR_C PF01314.18 KKK40345.1 - 7e-95 318.2 0.2 1e-94 317.7 0.0 1.3 2 0 0 2 2 2 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK40345.1 - 3.2e-65 219.7 0.1 4.8e-65 219.1 0.1 1.3 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain ParBc PF02195.18 KKK40346.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 2 0 0 2 2 2 0 ParB-like nuclease domain HATPase_c PF02518.26 KKK40347.1 - 4.2e-15 56.2 0.4 4.2e-15 56.2 0.4 1.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK40347.1 - 0.003 17.4 1.5 0.003 17.4 1.5 2.8 1 1 1 2 2 2 1 GHKL domain HATPase_c_2 PF13581.6 KKK40347.1 - 0.078 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Pox_A22 PF04848.13 KKK40348.1 - 0.0073 16.4 0.0 0.0083 16.2 0.0 1.0 1 0 0 1 1 1 1 Poxvirus A22 protein WxL PF13731.6 KKK40348.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 WxL domain surface cell wall-binding HAD_2 PF13419.6 KKK40349.1 - 6.3e-19 68.7 0.5 8.6e-19 68.3 0.5 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK40349.1 - 1.2e-09 38.8 0.0 2.2e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK40349.1 - 3e-07 30.4 0.0 4.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like MRP-S28 PF10213.9 KKK40349.1 - 0.083 13.3 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Glyoxalase PF00903.25 KKK40350.1 - 0.00011 22.4 0.0 0.00072 19.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KKK40350.1 - 0.022 15.6 0.0 0.026 15.3 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain Endonuclease_7 PF02945.15 KKK40351.1 - 1.8e-21 75.9 2.2 1.8e-21 75.9 2.2 2.5 1 1 0 2 2 2 1 Recombination endonuclease VII zf-RING_4 PF14570.6 KKK40351.1 - 0.028 14.2 6.1 0.76 9.6 0.1 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DNA_pol3_beta PF00712.19 KKK40351.1 - 0.036 14.2 0.0 0.078 13.1 0.0 1.5 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain zinc_ribbon_15 PF17032.5 KKK40351.1 - 0.049 14.4 1.7 0.049 14.4 1.7 2.6 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_4 PF13894.6 KKK40351.1 - 0.068 14.0 13.0 1.4 10.0 0.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger DUF295 PF03478.18 KKK40351.1 - 0.086 12.4 0.2 0.21 11.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) DZR PF12773.7 KKK40351.1 - 3.3 7.8 8.1 3.6e+02 1.3 8.1 3.0 1 1 0 1 1 1 0 Double zinc ribbon VATC PF18716.1 KKK40351.1 - 3.6 7.5 10.9 4.1 7.3 0.1 3.4 4 0 0 4 4 4 0 Vms1-associating treble clef domain Zn-ribbon_8 PF09723.10 KKK40351.1 - 8 6.7 9.4 23 5.2 0.2 3.5 3 1 2 5 5 5 0 Zinc ribbon domain Mut7-C PF01927.16 KKK40351.1 - 9 6.4 7.9 33 4.6 1.9 2.8 1 1 1 2 2 2 0 Mut7-C RNAse domain Hemagglutinin PF00509.18 KKK40353.1 - 0.01 14.3 2.7 0.016 13.7 2.7 1.2 1 0 0 1 1 1 0 Haemagglutinin Tctex-1 PF03645.13 KKK40353.1 - 0.044 14.0 0.6 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 Tctex-1 family HxlR PF01638.17 KKK40353.1 - 0.051 13.4 0.4 2.1 8.3 0.0 3.1 3 0 0 3 3 3 0 HxlR-like helix-turn-helix DUF3216 PF11505.8 KKK40353.1 - 0.059 13.6 0.3 0.16 12.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Baculo_PEP_C PF04513.12 KKK40353.1 - 0.092 12.8 12.8 0.031 14.3 2.8 3.4 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 KKK40353.1 - 0.23 12.0 1.1 8.1 7.1 0.7 3.3 2 1 0 2 2 2 0 YtxH-like protein DUF3887 PF13026.6 KKK40353.1 - 0.23 12.3 3.5 3.2 8.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) Glyco_hydro_57 PF03065.15 KKK40355.1 - 7e-39 133.9 0.4 1.6e-38 132.8 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF1925 PF09094.11 KKK40355.1 - 4.8e-28 97.3 5.0 5.1e-27 94.0 5.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1925) DUF1926 PF09095.11 KKK40355.1 - 3.7e-26 92.4 3.2 2.4e-14 53.6 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1926) Glyco_hydro_38N PF01074.22 KKK40355.1 - 7.5e-07 28.8 0.0 1.8e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain TSP_1 PF00090.19 KKK40356.1 - 5.5 7.3 7.3 12 6.2 7.3 1.7 1 1 0 1 1 1 0 Thrombospondin type 1 domain PCMT PF01135.19 KKK40357.1 - 4.5e-65 219.3 0.0 5.4e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 KKK40357.1 - 6.6e-09 35.8 0.0 9.1e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KKK40357.1 - 2.1e-07 30.9 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KKK40357.1 - 9.7e-05 23.3 0.0 0.00014 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KKK40357.1 - 0.00023 20.4 0.0 0.00053 19.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KKK40357.1 - 0.00095 19.8 0.0 0.0016 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK40357.1 - 0.0012 18.1 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.17 KKK40357.1 - 0.0047 16.1 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.6 KKK40357.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KKK40357.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 KKK40357.1 - 0.04 13.0 0.1 0.063 12.4 0.1 1.2 1 0 0 1 1 1 0 Fibrillarin DUF938 PF06080.12 KKK40357.1 - 0.048 13.4 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.12 KKK40357.1 - 0.097 13.3 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KKK40357.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_U32 PF01136.19 KKK40358.1 - 9.8e-76 254.0 0.3 9.8e-76 254.0 0.3 1.7 2 0 0 2 2 2 1 Peptidase family U32 FMN_red PF03358.15 KKK40359.1 - 3.7e-24 85.2 0.0 4.6e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKK40359.1 - 1.7e-06 27.9 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Exog_C PF18026.1 KKK40359.1 - 0.081 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain FMN_red PF03358.15 KKK40360.1 - 2.8e-28 98.6 0.0 3.2e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKK40360.1 - 2.3e-08 34.0 0.0 2.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Methyltransf_11 PF08241.12 KKK40361.1 - 2.5e-16 60.1 0.1 6.8e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK40361.1 - 2.5e-15 57.0 0.0 4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK40361.1 - 1.3e-11 44.5 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK40361.1 - 4.3e-10 40.2 0.0 1.2e-09 38.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK40361.1 - 4.3e-10 39.7 0.0 6.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK40361.1 - 1.5e-08 34.3 0.1 2.2e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KKK40361.1 - 5.1e-08 32.7 0.1 7.3e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CdhD PF03599.16 KKK40361.1 - 6e-08 31.8 0.0 8.8e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit MTS PF05175.14 KKK40361.1 - 4.8e-06 26.2 0.0 9.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KKK40361.1 - 1.6e-05 24.4 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 KKK40361.1 - 4e-05 23.3 0.0 6.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 KKK40361.1 - 4.2e-05 23.5 0.3 0.083 12.7 0.1 3.2 1 1 1 2 2 2 2 Hypothetical methyltransferase DREV PF05219.12 KKK40361.1 - 5.8e-05 22.3 0.0 9.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 KKK40361.1 - 0.00044 20.1 0.1 0.00072 19.4 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rsm22 PF09243.10 KKK40361.1 - 0.00053 19.4 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 CMAS PF02353.20 KKK40361.1 - 0.00075 18.9 0.1 0.00098 18.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.11 KKK40361.1 - 0.0082 15.2 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.17 KKK40361.1 - 0.013 15.0 0.8 0.12 11.8 0.8 2.2 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 KKK40361.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 KKK40361.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 KKK40361.1 - 0.022 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KKK40361.1 - 0.031 13.5 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_PK PF05891.12 KKK40361.1 - 0.092 12.3 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Gemin6 PF06372.12 KKK40361.1 - 0.097 12.2 1.2 0.26 10.8 0.2 2.1 3 0 0 3 3 3 0 Gemin6 protein NiFeSe_Hases PF00374.19 KKK40364.1 - 4.2e-11 42.4 0.0 4.7e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Oxidored_q6 PF01058.22 KKK40365.1 - 4.6e-19 68.6 0.1 1.4e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Fer4_14 PF13394.6 KKK40365.1 - 0.31 11.2 4.9 4.1 7.6 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain Ras PF00071.22 KKK40369.1 - 8.8e-29 100.2 0.0 1e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40369.1 - 2e-13 50.6 0.0 3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40369.1 - 7.8e-07 28.7 0.1 9.6e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Lactamase_B_2 PF12706.7 KKK40370.1 - 9.4e-11 41.6 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK40370.1 - 0.00013 21.9 0.1 0.00027 20.9 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF2061 PF09834.9 KKK40371.1 - 0.012 16.1 1.3 0.012 16.0 1.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) EamA PF00892.20 KKK40373.1 - 3.9e-06 27.1 6.9 4e-06 27.0 6.9 1.0 1 0 0 1 1 1 1 EamA-like transporter family DUF2970 PF11174.8 KKK40373.1 - 1.6 8.6 5.6 1.8 8.5 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) LRR_4 PF12799.7 KKK40376.1 - 1.2e-43 146.3 75.5 1.8e-11 44.1 2.0 6.4 3 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK40376.1 - 4.9e-24 83.9 38.8 2.8e-08 33.4 2.2 4.7 2 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KKK40376.1 - 2.3e-15 56.6 23.0 2.4e-05 23.9 4.8 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KKK40376.1 - 7.9e-11 41.1 33.1 0.051 13.7 0.5 8.8 7 1 1 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 KKK40376.1 - 2.3e-07 30.4 33.0 0.55 11.0 0.4 8.6 6 1 0 6 6 6 3 Leucine Rich Repeat Arm_3 PF16186.5 KKK40376.1 - 0.0083 15.7 7.9 4.8 6.8 0.2 5.2 5 1 0 5 5 5 2 Atypical Arm repeat Kelch_6 PF13964.6 KKK40376.1 - 0.073 13.4 0.0 8.6 6.8 0.0 2.7 2 0 0 2 2 2 0 Kelch motif UB2H PF14814.6 KKK40376.1 - 0.26 11.3 3.7 2e+02 2.1 0.0 5.1 1 1 1 5 5 5 0 Bifunctional transglycosylase second domain Pkip-1 PF06878.11 KKK40376.1 - 1.3 9.1 11.8 0.56 10.3 1.5 3.0 1 1 2 3 3 3 0 Pkip-1 protein LRR_2 PF07723.13 KKK40376.1 - 2.7 8.8 7.2 47 4.9 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat LapA_dom PF06305.11 KKK40379.1 - 0.14 12.0 0.4 0.34 10.7 0.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain YtkA PF13115.6 KKK40379.1 - 0.14 12.7 1.2 0.48 11.1 0.1 2.5 3 0 0 3 3 3 0 YtkA-like Big_1 PF02369.16 KKK40379.1 - 0.14 12.1 3.1 0.88 9.6 0.2 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) DUF1180 PF06679.12 KKK40379.1 - 0.14 12.5 0.1 0.24 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Invasin_D3 PF09134.10 KKK40379.1 - 0.96 9.8 4.5 0.57 10.5 0.3 2.7 3 0 0 3 3 3 0 Invasin, domain 3 ITI_HC_C PF06668.12 KKK40379.1 - 1.3 8.6 4.2 6.3 6.4 0.6 2.5 2 0 0 2 2 2 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Acetyltransf_3 PF13302.7 KKK40380.1 - 2e-24 86.8 0.0 2.4e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK40380.1 - 1.4e-10 41.4 0.1 2.1e-10 40.8 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KKK40380.1 - 2.2e-10 40.9 1.0 2.8e-10 40.5 1.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK40380.1 - 0.00026 21.3 0.0 0.00041 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK40380.1 - 0.033 14.1 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein ECH_1 PF00378.20 KKK40381.1 - 1.8e-33 115.9 0.0 1.9e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK40381.1 - 6.4e-15 55.5 0.0 7.2e-13 48.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HicB_lk_antitox PF15919.5 KKK40384.1 - 7.8e-09 35.7 0.0 8.1e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system MinE PF03776.14 KKK40384.1 - 0.0021 18.0 0.3 0.0029 17.6 0.2 1.5 1 1 0 1 1 1 1 Septum formation topological specificity factor MinE DUF1902 PF08972.11 KKK40384.1 - 0.0062 16.5 0.0 0.0066 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1902) Inos-1-P_synth PF01658.17 KKK40386.1 - 2.6e-30 104.9 2.5 1.6e-29 102.3 0.0 2.6 3 0 0 3 3 3 1 Myo-inositol-1-phosphate synthase CDP-OH_P_transf PF01066.21 KKK40387.1 - 8.1e-08 32.9 0.3 8.1e-08 32.9 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Bap31 PF05529.12 KKK40387.1 - 0.011 15.6 0.5 0.011 15.6 0.5 3.2 2 2 1 3 3 3 0 Bap31/Bap29 transmembrane region UPF0370 PF13980.6 KKK40387.1 - 0.41 10.7 4.9 0.55 10.3 1.6 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) NTP_transf_3 PF12804.7 KKK40388.1 - 6.4e-09 36.4 0.0 8.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KKK40388.1 - 3.7e-05 23.4 0.1 0.015 14.9 0.0 2.1 2 0 0 2 2 2 2 Nucleotidyl transferase Glyoxalase_4 PF13669.6 KKK40392.1 - 1.5e-17 63.9 0.0 2e-10 40.9 0.0 2.6 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KKK40392.1 - 6.4e-06 26.4 0.1 0.012 15.8 0.0 3.2 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KKK40392.1 - 0.0016 18.6 0.0 3.1 7.9 0.0 3.3 4 0 0 4 4 4 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KKK40393.1 - 3.2e-16 59.6 0.0 2.4e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KKK40393.1 - 0.00078 19.6 0.1 0.57 10.4 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KKK40393.1 - 0.035 14.0 4.2 1.6 8.7 0.4 2.8 2 2 0 2 2 2 0 Glyoxalase-like domain BcrAD_BadFG PF01869.20 KKK40395.1 - 4.4e-60 203.4 1.0 1e-40 139.9 2.0 2.1 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DUF2229 PF09989.9 KKK40395.1 - 3.9e-40 137.8 0.0 1.4e-39 135.9 0.0 2.0 2 0 0 2 2 2 1 CoA enzyme activase uncharacterised domain (DUF2229) AnmK PF03702.14 KKK40395.1 - 0.0029 16.8 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FGGY_N PF00370.21 KKK40395.1 - 0.048 13.2 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain MutL PF13941.6 KKK40395.1 - 0.097 11.2 0.2 0.16 10.5 0.2 1.3 1 0 0 1 1 1 0 MutL protein Fer4_12 PF13353.6 KKK40395.1 - 0.12 12.6 0.2 7.8 6.8 0.0 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Lipase_GDSL PF00657.22 KKK40395.1 - 0.19 11.7 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Radical_SAM PF04055.21 KKK40396.1 - 0.012 16.0 0.0 0.067 13.6 0.0 2.2 2 1 0 2 2 2 0 Radical SAM superfamily RNase_H_2 PF13482.6 KKK40397.1 - 6.7e-31 107.5 0.2 1.1e-30 106.8 0.2 1.3 1 0 0 1 1 1 1 RNase_H superfamily Cdd1 PF11731.8 KKK40397.1 - 0.056 13.7 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Pathogenicity locus IMS_HHH PF11798.8 KKK40397.1 - 0.12 12.8 0.0 0.69 10.4 0.0 2.3 2 0 0 2 2 2 0 IMS family HHH motif Flavodoxin_1 PF00258.25 KKK40399.1 - 1.8e-08 34.7 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Gpr1_Fun34_YaaH PF01184.19 KKK40399.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Radical_SAM PF04055.21 KKK40402.1 - 4.2e-13 50.0 0.0 6.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 KKK40402.1 - 1.6e-10 41.4 2.4 1.6e-10 41.4 2.4 2.2 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain SEC-C PF02810.15 KKK40402.1 - 6.9e-07 29.1 8.1 6.9e-07 29.1 8.1 2.1 2 0 0 2 2 2 1 SEC-C motif Fer4_12 PF13353.6 KKK40402.1 - 4.4e-06 27.0 0.0 1.3e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3641 PF12345.8 KKK40402.1 - 0.00033 20.7 3.0 0.038 14.0 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3641) Fer4_14 PF13394.6 KKK40402.1 - 0.001 19.2 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Sulfatase PF00884.23 KKK40403.1 - 1.5e-38 132.9 0.6 2e-38 132.5 0.6 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK40403.1 - 2.6e-06 27.3 0.0 6.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphoesterase PF04185.14 KKK40403.1 - 0.0067 15.7 0.0 0.14 11.3 0.1 2.6 3 0 0 3 3 3 1 Phosphoesterase family DUF4976 PF16347.5 KKK40403.1 - 0.0083 16.4 0.2 0.2 11.9 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 KKK40403.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.17 KKK40403.1 - 0.021 13.4 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Amidinotransf PF02274.17 KKK40404.1 - 2.5e-16 59.7 0.0 7.7e-10 38.4 0.0 3.0 2 1 0 2 2 2 2 Amidinotransferase Copine PF07002.16 KKK40404.1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Copine Peptidase_M28 PF04389.17 KKK40405.1 - 8.9e-12 45.1 0.0 7.1e-08 32.4 0.0 3.1 2 1 1 3 3 3 2 Peptidase family M28 Peptidase_M20 PF01546.28 KKK40405.1 - 0.00043 20.0 0.0 0.0014 18.3 0.0 1.6 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KKK40405.1 - 0.0022 17.1 0.0 0.0061 15.6 0.0 1.6 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Claudin_2 PF13903.6 KKK40405.1 - 0.42 10.3 6.8 0.064 13.0 2.1 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction N6_Mtase PF02384.16 KKK40406.1 - 5.2e-16 58.8 0.2 1.7e-14 53.8 0.2 2.2 1 1 0 1 1 1 1 N-6 DNA Methylase Eco57I PF07669.11 KKK40406.1 - 2.1e-07 31.4 0.1 7.9e-07 29.6 0.1 2.0 1 0 0 1 1 1 1 Eco57I restriction-modification methylase TaqI_C PF12950.7 KKK40406.1 - 0.00011 22.3 4.3 0.00021 21.3 0.0 3.0 3 1 0 3 3 3 1 TaqI-like C-terminal specificity domain UPF0020 PF01170.18 KKK40406.1 - 0.035 13.8 0.0 0.89 9.2 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF4130 PF13566.6 KKK40407.1 - 8.5e-11 42.1 0.5 1.9e-10 40.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4130 Radical_SAM PF04055.21 KKK40407.1 - 4.8e-06 27.0 0.2 1e-05 26.0 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK40407.1 - 0.078 13.2 0.3 0.22 11.8 0.3 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain Acyltransferase PF01553.21 KKK40407.1 - 0.084 12.5 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Acyltransferase DUF1978 PF09321.10 KKK40407.1 - 0.12 11.7 3.0 0.21 10.9 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) AAA_31 PF13614.6 KKK40408.1 - 1.1e-16 61.2 1.0 1.9e-16 60.5 1.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KKK40408.1 - 1e-14 54.7 0.2 1.4e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KKK40408.1 - 2.8e-09 36.6 1.1 5.6e-07 29.0 0.2 2.3 1 1 0 2 2 2 2 Anion-transporting ATPase ParA PF10609.9 KKK40408.1 - 6.7e-09 35.5 2.8 4.6e-08 32.8 2.8 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF87 PF01935.17 KKK40408.1 - 0.00033 20.8 0.4 0.00045 20.4 0.4 1.5 1 1 0 1 1 1 1 Helicase HerA, central domain Fer4_NifH PF00142.18 KKK40408.1 - 0.00063 19.3 0.8 0.0048 16.4 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KKK40408.1 - 0.00096 18.7 0.0 0.019 14.5 0.0 2.2 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 KKK40408.1 - 0.0013 17.7 0.1 0.0028 16.7 0.0 1.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KKK40408.1 - 0.002 18.5 0.0 0.0042 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MipZ PF09140.11 KKK40408.1 - 0.019 14.2 0.1 3.5 6.9 0.0 2.1 1 1 1 2 2 2 0 ATPase MipZ RsgA_GTPase PF03193.16 KKK40408.1 - 0.03 14.2 0.8 0.16 11.9 0.2 2.2 2 1 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KKK40408.1 - 0.036 14.0 0.2 2.8 7.8 0.0 2.8 2 1 0 3 3 3 0 NTPase CLP1_P PF16575.5 KKK40408.1 - 0.058 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KKK40408.1 - 0.062 12.5 2.1 0.1 11.8 0.8 2.1 2 1 0 2 2 2 0 NB-ARC domain Toprim_4 PF13662.6 KKK40408.1 - 0.073 13.5 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Toprim domain AAA_14 PF13173.6 KKK40408.1 - 0.094 12.8 0.5 0.24 11.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK40408.1 - 0.15 12.6 1.5 0.28 11.7 1.5 1.7 1 1 0 1 1 1 0 ABC transporter Acetyltransf_1 PF00583.25 KKK40409.1 - 8.4e-15 55.0 0.0 1e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK40409.1 - 3.4e-11 43.4 0.0 5.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK40409.1 - 2.5e-07 30.7 0.0 3.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK40409.1 - 5.7e-07 29.4 0.0 8.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KKK40409.1 - 8.6e-05 22.6 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KKK40409.1 - 0.00022 20.9 0.0 0.00042 20.0 0.0 1.4 2 0 0 2 2 2 1 GNAT acetyltransferase Acetyltransf_3 PF13302.7 KKK40409.1 - 0.0026 18.4 0.0 0.0031 18.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKK40409.1 - 0.095 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HAD_2 PF13419.6 KKK40410.1 - 4.5e-23 82.3 0.0 5.3e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK40410.1 - 1.3e-08 34.7 0.0 1.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK40410.1 - 2.4e-08 34.5 0.0 2.8e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK40410.1 - 0.0074 16.7 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKK40410.1 - 0.013 14.9 0.0 0.05 13.0 0.0 1.7 2 0 0 2 2 2 0 Putative Phosphatase Ribosomal_S2 PF00318.20 KKK40411.1 - 2.6e-25 88.9 3.0 2.3e-12 46.6 0.1 2.4 2 1 1 3 3 3 2 Ribosomal protein S2 HILPDA PF15220.6 KKK40412.1 - 0.024 14.8 1.1 0.091 12.9 0.3 2.2 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated DUF4239 PF14023.6 KKK40412.1 - 3.7 7.2 5.0 1.6 8.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) ODV-E18 PF10717.9 KKK40412.1 - 8.1 6.4 6.7 24 4.9 0.8 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 HD PF01966.22 KKK40413.1 - 1.6e-12 47.7 0.2 2.6e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KKK40413.1 - 0.0024 17.4 0.0 0.025 14.0 0.0 2.0 1 1 1 2 2 2 1 HDOD domain Aconitase_C PF00694.19 KKK40414.1 - 2e-17 63.7 0.0 2.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KKK40414.1 - 0.00012 21.8 0.0 0.001 18.8 0.0 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase PF00330.20 KKK40415.1 - 2.4e-100 336.8 0.2 2e-98 330.4 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 KKK40415.1 - 0.0035 16.1 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Thymidylate_kin PF02223.17 KKK40416.1 - 2.4e-48 164.3 0.1 2.7e-48 164.1 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KKK40416.1 - 0.00041 20.6 0.0 0.00049 20.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK40416.1 - 0.0014 19.1 0.1 0.0027 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain DZR PF12773.7 KKK40417.1 - 8e-08 32.2 0.4 0.00012 22.1 0.5 2.8 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK40417.1 - 9.8e-06 24.8 11.5 0.45 10.0 0.5 4.2 4 0 0 4 4 4 2 zinc-ribbon domain Nudix_N_2 PF14803.6 KKK40417.1 - 1.7e-05 24.6 7.7 0.69 9.9 0.2 4.1 4 0 0 4 4 4 2 Nudix N-terminal DNA_ligase_ZBD PF03119.16 KKK40417.1 - 8.3e-05 22.5 4.0 0.51 10.4 0.1 3.5 3 0 0 3 3 3 1 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_15 PF17032.5 KKK40417.1 - 0.00022 21.9 3.5 0.0011 19.7 0.9 2.3 2 1 0 2 2 2 1 zinc-ribbon family zf-LITAF-like PF10601.9 KKK40417.1 - 0.00022 21.4 10.7 0.0046 17.2 1.5 3.1 2 2 1 3 3 3 1 LITAF-like zinc ribbon domain zinc_ribbon_2 PF13240.6 KKK40417.1 - 0.00064 19.3 18.5 0.12 12.2 1.6 4.4 5 0 0 5 5 4 3 zinc-ribbon domain zf-C4_Topoisom PF01396.19 KKK40417.1 - 0.001 18.8 9.5 1.4 8.7 0.2 3.7 4 0 0 4 4 4 2 Topoisomerase DNA binding C4 zinc finger zf-NADH-PPase PF09297.11 KKK40417.1 - 0.0016 18.0 9.9 0.71 9.6 0.1 3.8 4 0 0 4 4 4 2 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 KKK40417.1 - 0.0062 16.6 6.4 3.7 7.7 0.1 4.2 4 0 0 4 4 4 0 Zinc ribbon domain C1_2 PF03107.16 KKK40417.1 - 0.0073 16.6 6.0 0.28 11.5 0.5 2.6 3 0 0 3 3 2 1 C1 domain C1_1 PF00130.22 KKK40417.1 - 0.0074 16.2 4.0 0.57 10.1 0.2 3.0 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KKK40417.1 - 0.0084 16.0 12.1 0.091 12.7 1.3 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 DUF2367 PF10164.9 KKK40417.1 - 0.0097 16.4 2.0 0.0097 16.4 2.0 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2367) Ribosomal_L33 PF00471.20 KKK40417.1 - 0.011 16.2 1.9 13 6.3 0.0 3.3 3 1 0 3 3 3 0 Ribosomal protein L33 ADK_lid PF05191.14 KKK40417.1 - 0.013 15.4 5.4 25 4.9 0.0 4.1 4 0 0 4 4 4 0 Adenylate kinase, active site lid GFA PF04828.14 KKK40417.1 - 0.024 15.0 4.6 24 5.3 0.0 3.9 3 1 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zinc-ribbons_6 PF07191.12 KKK40417.1 - 0.027 14.5 6.3 16 5.6 6.3 3.3 1 1 0 1 1 1 0 zinc-ribbons PHF5 PF03660.14 KKK40417.1 - 0.076 13.2 3.7 3.9 7.7 0.2 3.0 3 0 0 3 3 3 0 PHF5-like protein zf_UBZ PF18439.1 KKK40417.1 - 0.091 12.4 10.8 6 6.5 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger TackOD1 PF18551.1 KKK40417.1 - 0.092 12.4 3.8 0.2 11.3 0.1 2.3 3 0 0 3 3 2 0 Thaumarchaeal output domain 1 zf-ISL3 PF14690.6 KKK40417.1 - 0.095 13.4 7.5 15 6.4 0.2 3.8 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-Mss51 PF13824.6 KKK40417.1 - 0.097 12.8 1.7 14 5.9 0.0 2.6 2 2 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C3HC4_3 PF13920.6 KKK40417.1 - 0.099 12.5 7.9 3.6 7.5 1.1 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF1610 PF07754.11 KKK40417.1 - 0.11 12.5 1.1 0.11 12.5 1.1 4.0 5 0 0 5 5 3 0 Domain of unknown function (DUF1610) SCIMP PF15050.6 KKK40417.1 - 0.12 12.8 4.5 0.36 11.3 1.5 2.0 1 1 1 2 2 2 0 SCIMP protein DpnI PF06044.12 KKK40417.1 - 0.22 11.2 3.3 8.2 6.0 0.4 3.1 2 1 1 3 3 3 0 Dam-replacing family zf-dskA_traR PF01258.17 KKK40417.1 - 0.29 11.1 12.0 6.8 6.7 0.0 4.0 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger YacG PF03884.14 KKK40417.1 - 0.43 10.4 7.8 7.7 6.3 0.1 3.5 4 0 0 4 4 3 0 DNA gyrase inhibitor YacG DUF1272 PF06906.11 KKK40417.1 - 0.59 10.3 7.7 3.4 7.8 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) DUF4776 PF16003.5 KKK40417.1 - 0.63 9.0 2.8 0.4 9.6 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) RNA_POL_M_15KD PF02150.16 KKK40417.1 - 0.69 9.8 11.6 4.4 7.3 0.1 3.7 4 0 0 4 4 3 0 RNA polymerases M/15 Kd subunit DUF983 PF06170.12 KKK40417.1 - 1 9.8 7.3 6.2 7.3 0.2 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF983) HypA PF01155.19 KKK40417.1 - 1.1 9.3 5.1 36 4.4 5.1 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 KKK40417.1 - 1.1 8.9 15.7 12 5.7 0.4 4.2 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit PhnA_Zn_Ribbon PF08274.12 KKK40417.1 - 1.3 9.0 4.9 15 5.7 0.1 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon NOB1_Zn_bind PF08772.11 KKK40417.1 - 1.4 9.1 12.8 7.6 6.8 0.1 3.6 3 1 1 4 4 3 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.7 KKK40417.1 - 1.4 8.9 10.9 7.9 6.6 0.5 3.8 3 1 1 4 4 4 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 KKK40417.1 - 1.5 9.2 8.3 2.1e+02 2.4 0.0 3.8 3 1 0 3 3 3 0 Restriction alleviation protein Lar DUF2321 PF10083.9 KKK40417.1 - 1.6 8.3 5.4 0.38 10.4 0.2 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) zf_C2H2_10 PF18414.1 KKK40417.1 - 1.7 8.2 10.2 2.3 7.8 0.7 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger TF_Zn_Ribbon PF08271.12 KKK40417.1 - 1.9 8.0 10.8 51 3.5 0.3 3.6 3 1 0 3 3 3 0 TFIIB zinc-binding zf-BED PF02892.15 KKK40417.1 - 2 8.5 5.4 2 8.5 0.2 2.8 2 1 0 2 2 2 0 BED zinc finger Zn_ribbon_17 PF17120.5 KKK40417.1 - 3.2 7.5 6.8 6.9 6.4 0.6 2.8 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KKK40417.1 - 3.8 7.8 9.8 13 6.0 0.1 3.9 3 1 1 4 4 4 0 FANCL C-terminal domain YhfH PF14149.6 KKK40417.1 - 3.9 7.5 8.2 28 4.8 0.1 3.5 4 0 0 4 4 3 0 YhfH-like protein zf-HIT PF04438.16 KKK40417.1 - 5.6 6.9 12.0 13 5.7 3.5 3.2 3 0 0 3 3 3 0 HIT zinc finger DUF2089 PF09862.9 KKK40417.1 - 6.2 6.9 6.1 1.4 9.0 0.4 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF2089) Sgf11 PF08209.11 KKK40417.1 - 6.3 6.4 11.8 16 5.2 0.3 3.9 3 1 1 4 4 4 0 Sgf11 (transcriptional regulation protein) Zn_ribbon_recom PF13408.6 KKK40417.1 - 6.4 7.4 10.0 2.9 8.5 0.2 3.3 3 1 1 4 4 3 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.9 KKK40417.1 - 8 6.6 14.3 14 5.9 0.1 3.6 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.11 KKK40417.1 - 8.8 6.3 8.0 1.8 8.5 1.0 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Cript PF10235.9 KKK40417.1 - 8.9 7.0 8.0 19 5.9 0.1 3.3 3 1 0 3 3 3 0 Microtubule-associated protein CRIPT DUF4215 PF13948.6 KKK40417.1 - 9.5 6.8 12.8 2.2 8.8 0.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4215) DZR PF12773.7 KKK40418.1 - 1.1e-07 31.8 5.4 0.00011 22.1 1.2 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_9 PF14369.6 KKK40418.1 - 0.00021 21.5 2.9 0.088 13.1 0.7 3.2 3 0 0 3 3 3 1 zinc-ribbon zinc-ribbons_6 PF07191.12 KKK40418.1 - 0.00074 19.4 3.4 0.54 10.3 0.6 2.5 2 1 0 2 2 2 2 zinc-ribbons zinc_ribbon_2 PF13240.6 KKK40418.1 - 0.0042 16.7 6.5 0.0042 16.7 6.5 3.9 3 1 0 3 3 3 1 zinc-ribbon domain zf-LITAF-like PF10601.9 KKK40418.1 - 0.015 15.6 2.3 0.015 15.6 2.3 3.2 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.6 KKK40418.1 - 0.018 14.5 12.0 0.8 9.2 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.19 KKK40418.1 - 0.025 14.6 9.0 0.048 13.7 0.9 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 KKK40418.1 - 0.14 11.8 8.4 1.7 8.3 0.7 2.9 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 Nudix_N_2 PF14803.6 KKK40418.1 - 0.19 11.7 14.5 0.53 10.2 0.2 3.8 4 0 0 4 4 4 0 Nudix N-terminal MqsA_antitoxin PF15731.5 KKK40418.1 - 0.22 11.6 6.2 0.8 9.8 1.2 3.2 2 1 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA GFA PF04828.14 KKK40418.1 - 0.27 11.6 12.5 1.4 9.3 3.8 3.2 1 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme PknG_rubred PF16919.5 KKK40418.1 - 0.57 10.4 3.1 0.45 10.7 0.8 2.0 2 1 0 2 2 2 0 Protein kinase G rubredoxin domain zf-CHY PF05495.12 KKK40418.1 - 0.62 10.6 12.2 0.92 10.0 7.7 2.7 2 1 0 2 2 2 0 CHY zinc finger Zn-ribbon_8 PF09723.10 KKK40418.1 - 2.2 8.4 10.2 0.8 9.9 1.5 3.1 3 0 0 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.14 KKK40418.1 - 3.2 7.8 0.0 3.2 7.8 0.0 3.4 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-C3HC4 PF00097.25 KKK40418.1 - 3.5 7.6 12.0 0.2 11.5 1.3 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF983 PF06170.12 KKK40418.1 - 6.1 7.3 6.4 10 6.6 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF983) HTH_10 PF04967.12 KKK40421.1 - 2.7e-10 39.9 0.1 4.3e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 HTH DNA binding domain FeoC PF09012.10 KKK40421.1 - 0.042 13.9 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_11 PF08279.12 KKK40421.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 HTH domain WG_beta_rep PF14903.6 KKK40421.1 - 0.14 12.5 0.9 2.9 8.3 0.1 2.9 3 0 0 3 3 3 0 WG containing repeat MarR_2 PF12802.7 KKK40421.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 KKK40421.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 KKK40421.1 - 0.17 11.4 1.7 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HEAT_2 PF13646.6 KKK40422.1 - 1.3e-32 112.0 1.4 4.1e-09 36.7 0.0 5.3 4 1 0 5 5 5 4 HEAT repeats HEAT_PBS PF03130.16 KKK40422.1 - 1.9e-10 40.4 0.0 0.48 11.2 0.0 6.5 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.22 KKK40422.1 - 1.5e-05 24.8 0.3 34 5.1 0.0 7.1 9 0 0 9 9 9 0 HEAT repeat Arm PF00514.23 KKK40422.1 - 0.0072 16.3 2.4 6.9 6.9 0.0 5.6 7 1 1 8 8 8 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KKK40422.1 - 0.037 14.2 5.8 0.037 14.2 1.9 3.0 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Imm30 PF15565.6 KKK40422.1 - 0.049 13.7 4.1 0.41 10.7 0.2 3.8 4 0 0 4 4 4 0 Immunity protein 30 Vitellogenin_N PF01347.22 KKK40422.1 - 0.31 9.4 4.9 0.49 8.7 0.0 2.9 3 1 0 3 3 3 0 Lipoprotein amino terminal region FrhB_FdhB_C PF04432.13 KKK40423.1 - 7e-37 126.6 0.0 1.4e-36 125.6 0.0 1.6 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK40423.1 - 4.7e-19 68.3 0.0 1.2e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Fer4_10 PF13237.6 KKK40423.1 - 1.4e-06 28.3 12.5 3.3e-06 27.1 10.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK40423.1 - 2.5e-06 27.0 17.1 0.0033 17.2 4.2 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KKK40423.1 - 5e-06 26.6 9.5 0.011 16.2 1.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK40423.1 - 1.1e-05 25.5 12.0 2.5e-05 24.3 10.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40423.1 - 0.00012 22.0 12.7 0.035 14.2 1.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK40423.1 - 0.00052 20.4 13.1 0.2 12.1 2.6 2.7 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK40423.1 - 0.0029 18.2 15.4 0.34 11.5 16.2 3.1 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40423.1 - 0.0051 16.8 21.5 0.026 14.6 4.3 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK40423.1 - 0.0071 16.9 15.5 0.24 12.0 2.3 2.8 2 1 3 5 5 4 4 4Fe-4S dicluster domain SurE PF01975.17 KKK40423.1 - 0.024 14.4 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 Survival protein SurE Fer4_21 PF14697.6 KKK40423.1 - 0.19 11.9 17.7 0.2 11.8 14.4 2.5 2 1 0 2 2 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK40423.1 - 0.72 10.8 19.4 3.1 8.8 5.0 3.5 3 1 2 5 5 4 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 KKK40423.1 - 3.6 7.8 10.1 41 4.4 10.1 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK40423.1 - 7.2 7.2 13.4 16 6.1 1.8 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Gtr1_RagA PF04670.12 KKK40424.1 - 1.5e-20 73.6 0.0 2.8e-20 72.7 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK40424.1 - 3.1e-11 43.0 0.0 5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK40424.1 - 1.3e-09 37.9 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK40424.1 - 6.9e-09 35.4 0.0 9.7e-07 28.4 0.0 2.3 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK40424.1 - 4e-05 23.8 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DDE_Tnp_IS66 PF03050.14 KKK40430.1 - 0.027 13.9 0.1 0.58 9.6 0.1 2.3 1 1 0 1 1 1 0 Transposase IS66 family REC1 PF18501.1 KKK40430.1 - 0.033 14.1 2.8 0.033 14.1 0.2 1.9 1 1 1 2 2 2 0 Alpha helical recognition lobe domain DZR PF12773.7 KKK40430.1 - 0.039 14.0 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon DDE_Tnp_IS240 PF13610.6 KKK40430.1 - 0.073 13.3 0.2 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 DDE domain zf-ribbon_3 PF13248.6 KKK40430.1 - 0.34 10.4 1.7 0.33 10.4 0.3 1.7 2 0 0 2 2 2 0 zinc-ribbon domain N6_Mtase PF02384.16 KKK40435.1 - 2.5e-11 43.4 7.0 1.6e-10 40.7 2.0 2.8 2 1 0 2 2 2 1 N-6 DNA Methylase Eco57I PF07669.11 KKK40435.1 - 2.1e-09 37.8 0.2 2.1e-09 37.8 0.2 3.1 3 0 0 3 3 3 1 Eco57I restriction-modification methylase TaqI_C PF12950.7 KKK40435.1 - 2.3e-09 37.4 7.8 2.3e-09 37.4 7.8 3.7 3 1 1 4 4 4 1 TaqI-like C-terminal specificity domain Methyltransf_23 PF13489.6 KKK40435.1 - 0.001 19.0 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_2 PF07992.14 KKK40436.1 - 1.3e-47 162.5 0.0 1.6e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK40436.1 - 2.5e-21 76.0 1.4 1.2e-20 73.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKK40436.1 - 2.7e-13 50.3 0.3 2.7e-13 50.3 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KKK40436.1 - 0.015 15.2 0.3 0.035 14.0 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK40436.1 - 0.046 13.1 0.3 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mqo PF06039.15 KKK40436.1 - 0.063 11.8 3.4 0.17 10.4 0.7 2.3 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF2220 PF09983.9 KKK40436.1 - 0.13 11.6 0.4 0.49 9.7 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) FAD_binding_2 PF00890.24 KKK40436.1 - 0.64 9.0 2.3 13 4.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain PAS_4 PF08448.10 KKK40437.1 - 1.3e-27 96.2 0.0 8.6e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KKK40437.1 - 1.5e-18 66.8 0.0 9.4e-09 35.3 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKK40437.1 - 2.8e-15 56.4 5.9 8.8e-08 32.3 0.1 3.4 3 1 0 3 3 3 2 PAS domain HATPase_c PF02518.26 KKK40437.1 - 4.6e-15 56.1 2.1 8e-15 55.3 1.4 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KKK40437.1 - 2.8e-10 40.0 0.1 4.2e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain HATPase_c_2 PF13581.6 KKK40437.1 - 6.9e-05 22.8 0.1 0.0016 18.4 0.0 2.4 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain Spore_IV_A PF09547.10 KKK40437.1 - 0.0012 17.9 8.7 0.002 17.2 8.7 1.3 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) HATPase_c_5 PF14501.6 KKK40437.1 - 0.0015 18.4 8.2 0.025 14.5 8.2 2.8 1 1 0 1 1 1 1 GHKL domain HisKA PF00512.25 KKK40437.1 - 0.005 16.8 0.1 0.016 15.2 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Ribosomal_S24e PF01282.19 KKK40437.1 - 0.044 13.7 1.2 5.1 7.1 0.0 3.3 4 0 0 4 4 4 0 Ribosomal protein S24e MLTR_LBD PF17765.1 KKK40437.1 - 0.17 12.0 0.2 0.41 10.8 0.1 1.6 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain DUF3023 PF11224.8 KKK40437.1 - 0.17 11.7 7.6 0.42 10.5 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3023) RXLR PF16810.5 KKK40437.1 - 2 8.8 5.0 29 5.1 0.1 3.1 3 0 0 3 3 3 0 RXLR phytopathogen effector protein, Avirulence activity LRRFIP PF09738.9 KKK40437.1 - 2.2 7.7 10.9 0.64 9.4 2.5 3.1 3 1 0 3 3 3 0 LRRFIP family HATPase_c PF02518.26 KKK40438.1 - 3.7e-12 46.7 0.1 4e-12 46.6 0.1 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK40438.1 - 0.0017 18.2 0.1 0.0027 17.6 0.1 1.4 1 1 0 1 1 1 1 GHKL domain GATase PF00117.28 KKK40440.1 - 2.3e-19 69.9 0.0 3.3e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKK40440.1 - 3.3e-08 33.5 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KKK40440.1 - 0.00066 19.5 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 KKK40440.1 - 0.0043 16.7 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CBM26 PF16738.5 KKK40440.1 - 0.16 12.3 0.1 0.26 11.6 0.1 1.3 1 0 0 1 1 1 0 Starch-binding module 26 HATPase_c PF02518.26 KKK40441.1 - 1.1e-23 83.8 1.8 4.7e-22 78.6 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK40441.1 - 3.4e-11 43.0 1.7 1.5e-10 40.9 1.7 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KKK40441.1 - 1.8e-06 28.1 0.2 8.3e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 PAS domain SirA PF10747.9 KKK40441.1 - 0.00023 21.5 3.3 0.0003 21.1 0.5 2.4 1 1 1 2 2 2 1 Sporulation inhibitor of replication protein SirA HATPase_c_3 PF13589.6 KKK40441.1 - 0.00044 20.1 0.5 0.0079 16.0 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1700 PF08006.11 KKK40442.1 - 0.087 12.4 0.4 0.086 12.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) GCFC PF07842.12 KKK40443.1 - 0.022 14.4 0.1 0.024 14.3 0.1 1.0 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein Pec_lyase_C PF00544.19 KKK40443.1 - 0.057 13.0 0.2 0.059 13.0 0.2 1.1 1 0 0 1 1 1 0 Pectate lyase Ribosomal_L32e PF01655.18 KKK40443.1 - 0.073 13.5 0.0 0.082 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L32 F-box PF00646.33 KKK40443.1 - 0.078 12.9 0.1 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 F-box domain PMC2NT PF08066.12 KKK40443.1 - 0.095 13.4 0.4 0.1 13.3 0.4 1.1 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Exonuc_VII_S PF02609.16 KKK40443.1 - 0.11 12.6 1.1 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Exonuclease VII small subunit Methyltransf_11 PF08241.12 KKK40444.1 - 4e-14 53.0 0.0 4.2e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK40444.1 - 1.9e-10 40.7 0.8 1.8e-07 31.1 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KKK40444.1 - 1.5e-09 38.5 0.2 1.3e-06 29.0 0.0 2.3 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KKK40444.1 - 1.7e-08 34.4 0.1 2.6e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK40444.1 - 1.8e-07 30.7 0.1 6e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK40444.1 - 7.8e-06 26.6 0.7 7.2e-05 23.5 0.7 2.2 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KKK40444.1 - 0.00021 20.9 0.0 0.059 13.0 0.0 2.2 2 0 0 2 2 2 2 Methionine biosynthesis protein MetW DUF3655 PF12379.8 KKK40444.1 - 0.03 14.6 1.5 0.055 13.8 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3655) CMAS PF02353.20 KKK40444.1 - 0.031 13.6 0.2 0.044 13.1 0.2 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 KKK40444.1 - 0.062 12.7 0.1 0.17 11.3 0.0 1.7 1 1 1 2 2 2 0 Tellurite resistance protein TehB Gtr1_RagA PF04670.12 KKK40445.1 - 1e-22 80.7 1.1 1.4e-22 80.2 0.5 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK40445.1 - 2e-20 73.0 0.1 2.9e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK40445.1 - 9.5e-07 29.1 0.0 3.1e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK40445.1 - 1.8e-06 27.7 0.1 4.6e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 KKK40445.1 - 2.8e-06 26.9 0.2 1.7e-05 24.3 0.0 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK40445.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK40445.1 - 0.0021 17.3 2.1 0.84 8.7 0.3 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 KKK40445.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PI_PP_I PF18363.1 KKK40445.1 - 0.72 10.1 3.8 11 6.2 0.1 3.1 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain VWA PF00092.28 KKK40446.1 - 1.9e-14 54.3 0.0 2.8e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KKK40446.1 - 1.1e-12 48.5 0.0 2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KKK40446.1 - 3.8e-10 39.9 0.0 6.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like FANCL_C PF11793.8 KKK40446.1 - 0.0003 20.9 18.2 0.0016 18.6 3.8 2.6 2 0 0 2 2 2 2 FANCL C-terminal domain Prok-RING_1 PF14446.6 KKK40446.1 - 0.00033 20.5 19.9 0.0017 18.2 5.8 3.4 2 2 0 2 2 2 2 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KKK40446.1 - 0.0016 18.7 28.1 0.0099 16.2 6.5 2.8 3 0 0 3 3 3 2 Ring finger domain zf-RING_9 PF13901.6 KKK40446.1 - 0.0025 17.9 16.4 0.013 15.5 5.9 2.3 2 0 0 2 2 2 2 Putative zinc-RING and/or ribbon zf-RING-like PF08746.11 KKK40446.1 - 0.0051 17.1 26.0 0.024 14.9 8.2 3.3 3 1 0 3 3 3 2 RING-like domain VWA_3 PF13768.6 KKK40446.1 - 0.0061 16.5 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KKK40446.1 - 0.034 13.7 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 zf-HC5HC2H PF13771.6 KKK40446.1 - 0.087 13.1 12.4 0.26 11.6 2.6 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain Auto_anti-p27 PF06677.12 KKK40446.1 - 0.32 11.2 8.6 9.2 6.5 0.2 4.0 4 0 0 4 4 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PHD PF00628.29 KKK40446.1 - 2.6 8.0 26.4 1.6 8.7 8.1 3.6 3 1 1 4 4 4 0 PHD-finger zf-ANAPC11 PF12861.7 KKK40446.1 - 9.9 6.3 14.1 5.4 7.1 4.1 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2934 PF11154.8 KKK40447.1 - 0.085 12.6 0.7 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) MtrH PF02007.18 KKK40448.1 - 3.3e-32 111.8 0.0 6.9e-32 110.7 0.0 1.5 1 1 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit Glyco_hydro_38N PF01074.22 KKK40450.1 - 3e-40 138.4 0.0 3.7e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain PSI_PSAK PF01241.18 KKK40450.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK Phosphodiest PF01663.22 KKK40451.1 - 4e-27 95.7 0.1 3.7e-24 86.0 0.0 2.9 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK40451.1 - 3.4e-12 46.4 0.0 1e-06 28.4 0.0 3.2 3 0 0 3 3 3 3 Sulfatase Metalloenzyme PF01676.18 KKK40451.1 - 0.066 12.6 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF229 PF02995.17 KKK40451.1 - 0.072 11.7 0.1 0.093 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 KKK40451.1 - 0.24 10.4 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) N6_N4_Mtase PF01555.18 KKK40452.1 - 1.4e-39 136.2 0.1 1.4e-39 136.2 0.1 1.7 1 1 1 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 KKK40452.1 - 0.001 18.8 3.4 0.0012 18.6 2.3 1.6 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase UPF0020 PF01170.18 KKK40452.1 - 0.0081 15.9 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KKK40452.1 - 0.0093 16.6 0.0 2 9.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 KKK40452.1 - 0.03 14.0 0.1 0.087 12.6 0.1 1.6 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 KKK40452.1 - 0.14 12.8 0.0 1.5 9.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ras PF00071.22 KKK40453.1 - 1.5e-39 135.2 1.4 2.3e-39 134.6 1.4 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40453.1 - 1.2e-25 90.0 0.2 2e-25 89.3 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40453.1 - 6.1e-12 45.3 0.1 9.3e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK40453.1 - 6.9e-06 25.6 0.6 1.2e-05 24.8 0.6 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Robl_LC7 PF03259.17 KKK40453.1 - 6.5e-05 22.6 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain MMR_HSR1 PF01926.23 KKK40453.1 - 0.00081 19.5 0.1 0.002 18.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK40453.1 - 0.0057 15.9 2.5 0.027 13.6 2.5 2.2 1 1 0 1 1 1 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KKK40453.1 - 0.0081 16.1 0.6 0.35 10.8 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KKK40453.1 - 0.029 13.8 1.1 0.055 12.9 0.4 1.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KKK40453.1 - 0.12 12.4 0.6 0.68 10.0 0.4 2.3 1 1 1 2 2 2 0 AAA domain Ras PF00071.22 KKK40454.1 - 4.3e-38 130.5 1.8 7.1e-38 129.8 1.8 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40454.1 - 3.4e-26 91.8 0.4 5.5e-26 91.1 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40454.1 - 4.7e-12 45.7 0.1 7.2e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK40454.1 - 1.2e-06 28.1 0.4 1.9e-06 27.4 0.4 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Robl_LC7 PF03259.17 KKK40454.1 - 0.0021 17.8 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain MMR_HSR1 PF01926.23 KKK40454.1 - 0.0084 16.2 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 KKK40454.1 - 0.019 14.9 0.2 0.078 12.9 0.0 1.9 1 1 1 2 2 2 0 NTPase SRPRB PF09439.10 KKK40454.1 - 0.02 14.3 1.5 0.13 11.7 0.4 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKK40454.1 - 0.12 12.3 0.6 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Laminin_G_3 PF13385.6 KKK40456.1 - 2.3e-18 66.8 0.2 2.3e-18 66.8 0.2 3.2 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily CarboxypepD_reg PF13620.6 KKK40456.1 - 8.2e-07 29.2 2.4 0.062 13.6 0.0 4.5 4 0 0 4 4 4 2 Carboxypeptidase regulatory-like domain DUF2341 PF10102.9 KKK40456.1 - 2.5e-06 28.0 1.2 2.3e-05 24.9 0.7 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2341) Big_1 PF02369.16 KKK40456.1 - 1.5 8.9 8.6 2.5 8.2 0.1 3.8 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 1) Ras PF00071.22 KKK40457.1 - 7.5e-37 126.4 0.3 1.1e-36 125.9 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40457.1 - 8.9e-26 90.5 0.2 1.4e-25 89.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40457.1 - 1.6e-11 44.0 0.0 4.2e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK40457.1 - 4.1e-06 26.3 0.1 1e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK40457.1 - 8.3e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK40457.1 - 0.0014 18.7 0.2 0.0027 17.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK40457.1 - 0.0038 17.2 0.1 0.62 9.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Robl_LC7 PF03259.17 KKK40457.1 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain FeoB_N PF02421.18 KKK40457.1 - 0.0082 15.7 0.2 1.2 8.7 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B ATPase_2 PF01637.18 KKK40457.1 - 0.013 15.5 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KKK40457.1 - 0.017 14.6 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region dCache_1 PF02743.18 KKK40457.1 - 0.018 14.8 0.0 0.07 12.9 0.0 2.0 2 1 0 2 2 2 0 Cache domain MAPKK1_Int PF08923.10 KKK40457.1 - 0.03 14.1 0.0 0.093 12.6 0.0 1.8 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting TniB PF05621.11 KKK40457.1 - 0.036 13.5 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 KKK40457.1 - 0.089 12.8 0.2 0.19 11.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KKK40457.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IGPD PF00475.18 KKK40459.1 - 6.6e-56 188.6 2.1 8.1e-56 188.3 2.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DNTTIP1_dimer PF18192.1 KKK40459.1 - 0.04 14.3 0.2 0.075 13.4 0.2 1.3 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain DUF5335 PF17269.2 KKK40459.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Glyco_hydro_4 PF02056.16 KKK40460.1 - 0.0011 18.5 0.1 0.0011 18.5 0.1 1.0 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase NB-ARC PF00931.22 KKK40462.1 - 0.0022 17.2 0.0 0.0022 17.2 0.0 1.0 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.6 KKK40462.1 - 0.0044 16.8 0.3 0.0044 16.8 0.3 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK40462.1 - 0.011 16.1 0.0 0.011 16.1 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 KKK40462.1 - 0.016 14.7 0.1 0.016 14.7 0.1 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_30 PF13604.6 KKK40462.1 - 0.021 14.5 0.0 0.021 14.5 0.0 1.0 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KKK40462.1 - 0.027 13.6 0.0 0.027 13.6 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit Viral_helicase1 PF01443.18 KKK40462.1 - 0.027 14.2 0.0 0.028 14.2 0.0 1.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KKK40462.1 - 0.04 14.4 0.0 0.04 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KKK40462.1 - 0.059 13.1 0.1 0.062 13.1 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KKK40462.1 - 0.067 13.1 0.1 0.067 13.1 0.1 1.0 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KKK40462.1 - 0.077 13.1 0.1 0.08 13.1 0.1 1.0 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KKK40462.1 - 0.099 12.2 0.2 0.099 12.2 0.2 1.0 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KKK40462.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK40462.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KKK40462.1 - 0.13 12.8 0.1 0.15 12.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKK40462.1 - 0.15 12.6 0.0 0.15 12.6 0.0 1.1 1 0 0 1 1 1 0 ABC transporter Fer4_8 PF13183.6 KKK40463.1 - 3.5e-09 37.0 5.7 8.6e-09 35.7 5.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK40463.1 - 5.1e-09 36.2 5.5 1e-08 35.2 5.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK40463.1 - 5.3e-09 36.5 18.5 1.2e-05 25.8 10.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK40463.1 - 7.7e-07 29.6 6.2 2.3e-06 28.1 6.2 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK40463.1 - 3.9e-06 26.9 12.3 7.8e-05 22.7 12.4 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK40463.1 - 4.6e-06 27.5 9.3 4.6e-06 27.5 9.3 2.2 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK40463.1 - 3.7e-05 23.9 9.2 0.051 14.1 0.3 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK40463.1 - 0.00039 20.5 9.5 0.00097 19.2 9.5 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40463.1 - 0.004 17.2 12.9 0.0097 15.9 1.7 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4 PF00037.27 KKK40463.1 - 0.019 14.7 19.4 0.033 14.0 5.7 2.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK40463.1 - 0.025 15.4 12.1 0.13 13.1 1.1 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK40463.1 - 0.032 14.4 10.2 0.96 9.7 2.6 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40463.1 - 0.041 14.0 17.6 0.05 13.7 3.9 2.7 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK40463.1 - 0.14 13.2 13.4 0.91 10.6 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK40463.1 - 2.8 8.6 11.8 1.5 9.4 2.9 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I CCG PF02754.16 KKK40464.1 - 1.7e-21 76.2 3.3 9.8e-13 48.1 0.0 2.6 2 0 0 2 2 2 2 Cysteine-rich domain RVT_thumb PF06817.14 KKK40464.1 - 0.13 12.1 0.0 0.5 10.3 0.0 2.0 1 0 0 1 1 1 0 Reverse transcriptase thumb domain EamA PF00892.20 KKK40465.1 - 5.1e-29 101.2 39.5 4.6e-18 65.7 20.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KKK40465.1 - 9.9e-06 25.0 1.7 9.9e-06 25.0 1.7 2.3 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport URO-D PF01208.17 KKK40472.1 - 4.8e-09 35.8 0.0 5.5e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Glyco_hydro_1 PF00232.18 KKK40474.1 - 2.6e-170 566.7 0.5 3e-170 566.5 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Spore_II_R PF09551.10 KKK40475.1 - 0.47 10.9 5.6 0.11 13.0 1.8 1.9 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) PDDEXK_1 PF12705.7 KKK40476.1 - 0.0039 17.1 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily LRR_8 PF13855.6 KKK40477.1 - 7.9e-09 35.1 10.2 0.00012 21.8 5.6 4.0 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KKK40477.1 - 7e-06 26.3 14.7 0.078 13.4 0.6 4.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) DUF1374 PF07118.11 KKK40477.1 - 4.3 7.9 11.5 4.4 7.9 0.5 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1374) SEC-C PF02810.15 KKK40479.1 - 3.6e-08 33.2 10.0 3.6e-08 33.2 10.0 2.1 2 0 0 2 2 2 1 SEC-C motif Rep_fac-A_3 PF08661.11 KKK40479.1 - 0.062 13.7 0.0 0.08 13.3 0.0 1.2 1 0 0 1 1 1 0 Replication factor A protein 3 SCP2 PF02036.17 KKK40480.1 - 1.8e-13 50.9 0.1 2.4e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KKK40480.1 - 0.071 13.4 0.0 0.085 13.1 0.0 1.2 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal DUF92 PF01940.16 KKK40482.1 - 0.003 17.0 0.5 0.003 17.0 0.5 1.9 1 1 1 2 2 2 1 Integral membrane protein DUF92 SieB PF14163.6 KKK40482.1 - 0.8 9.2 6.5 0.13 11.8 0.2 2.4 1 1 2 3 3 3 0 Super-infection exclusion protein B E1-E2_ATPase PF00122.20 KKK40482.1 - 2.8 7.4 8.7 0.33 10.4 0.2 2.7 2 1 1 3 3 3 0 E1-E2 ATPase DUF1129 PF06570.11 KKK40482.1 - 5.1 6.5 14.0 0.22 11.0 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) FAD_binding_2 PF00890.24 KKK40483.1 - 1.5e-13 50.6 0.1 1.4e-05 24.4 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KKK40483.1 - 1e-11 44.4 0.0 4.4e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 KKK40483.1 - 1.2e-09 38.0 0.1 2.5e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK40483.1 - 1.5e-09 37.6 0.1 1e-06 28.3 0.1 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK40483.1 - 7.2e-07 29.1 0.0 0.0018 18.0 0.1 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK40483.1 - 8.1e-07 28.5 0.4 6.7e-06 25.5 0.3 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK40483.1 - 3.6e-06 26.4 0.0 0.00011 21.5 0.0 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KKK40483.1 - 4.6e-06 26.0 0.6 9.2e-06 25.0 0.6 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KKK40483.1 - 3.5e-05 23.0 0.0 0.0014 17.8 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK40483.1 - 5.9e-05 23.2 0.1 0.0013 18.9 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK40483.1 - 0.0003 19.6 0.1 0.0005 18.9 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KKK40483.1 - 0.0062 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KKK40483.1 - 0.011 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MSV199 PF10553.9 KKK40483.1 - 0.062 13.5 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 MSV199 domain Pyr_redox PF00070.27 KKK40483.1 - 0.079 13.5 0.2 0.26 11.9 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PcrB PF01884.17 KKK40484.1 - 4.6e-54 183.3 0.1 5.6e-54 183.0 0.1 1.0 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.21 KKK40484.1 - 5.6e-07 29.3 0.2 8.5e-06 25.4 0.0 2.6 3 1 0 3 3 3 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 KKK40484.1 - 0.00048 19.6 0.1 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator NMO PF03060.15 KKK40484.1 - 0.0008 18.9 0.1 0.01 15.3 0.0 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase DHO_dh PF01180.21 KKK40484.1 - 0.001 18.3 0.5 0.0019 17.5 0.1 1.6 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Dus PF01207.17 KKK40484.1 - 0.0017 17.5 0.1 0.37 9.8 0.1 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IMPDH PF00478.25 KKK40484.1 - 0.0022 17.1 0.1 0.037 13.0 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 KKK40484.1 - 0.018 14.4 0.1 0.067 12.5 0.1 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase ThiG PF05690.14 KKK40484.1 - 0.026 13.8 0.5 0.9 8.8 0.1 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG NanE PF04131.14 KKK40484.1 - 0.031 13.4 0.5 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PEP_hydrolase PF09370.10 KKK40484.1 - 0.033 13.4 0.2 0.55 9.4 0.1 2.4 2 1 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like FMN_dh PF01070.18 KKK40484.1 - 0.072 12.1 0.0 0.3 10.1 0.0 1.9 2 1 0 2 2 2 0 FMN-dependent dehydrogenase ECH_1 PF00378.20 KKK40489.1 - 1.5e-32 112.9 0.0 1.8e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK40489.1 - 4.7e-18 65.8 0.0 5.6e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fer4 PF00037.27 KKK40490.1 - 8.1e-09 34.9 17.8 1.2e-05 24.9 2.0 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK40490.1 - 1.4e-08 35.1 23.5 7.3e-07 29.7 12.1 3.0 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK40490.1 - 2.6e-08 33.9 25.1 4.3e-07 30.0 12.2 2.4 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK40490.1 - 7.5e-06 26.0 12.1 7.5e-06 26.0 12.1 2.5 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40490.1 - 6.8e-05 22.8 12.3 0.0021 18.1 2.2 3.4 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK40490.1 - 0.00018 22.4 9.5 0.1 13.6 0.5 2.8 1 1 2 3 3 3 3 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK40490.1 - 0.00021 21.3 13.0 0.00021 21.3 13.0 2.1 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40490.1 - 0.0021 18.1 1.7 0.0021 18.1 1.7 3.7 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK40490.1 - 0.011 16.2 15.3 0.21 12.1 0.5 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK40490.1 - 0.021 15.0 6.0 0.021 15.0 6.0 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK40490.1 - 0.022 15.5 7.9 1.8 9.4 1.0 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 KKK40490.1 - 0.023 15.2 2.9 0.023 15.2 2.9 3.2 4 0 0 4 4 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK40490.1 - 1.8 9.2 22.4 0.37 11.4 2.0 3.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK40490.1 - 3.9 8.1 12.6 9.3 6.9 2.9 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_6 PF12837.7 KKK40491.1 - 4.5e-09 36.0 14.3 0.00025 21.0 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK40491.1 - 5.9e-08 33.2 5.1 6e-05 23.6 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK40491.1 - 1.8e-07 31.2 6.2 4e-07 30.1 6.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK40491.1 - 1.1e-06 28.2 12.3 6.3e-05 22.6 4.5 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK40491.1 - 7.5e-06 26.8 5.6 0.00034 21.5 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK40491.1 - 2.2e-05 24.5 9.6 0.0053 16.8 1.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK40491.1 - 0.00038 20.5 9.6 0.0022 18.1 9.6 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40491.1 - 0.00052 20.0 17.0 0.021 14.9 5.1 2.7 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK40491.1 - 0.00087 19.8 8.1 0.0017 18.9 8.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK40491.1 - 0.0023 18.3 11.9 0.0051 17.2 1.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_3 PF12798.7 KKK40491.1 - 0.19 12.7 16.8 0.38 11.8 5.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 KKK40491.1 - 0.31 11.5 15.1 0.078 13.4 5.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK40491.1 - 1.9 9.2 11.8 7.6 7.4 0.3 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Arf PF00025.21 KKK40497.1 - 1.8e-10 40.5 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK40497.1 - 2.2e-09 37.1 0.2 2.7e-09 36.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40497.1 - 4.7e-06 26.8 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KKK40497.1 - 0.00051 19.5 0.1 0.00069 19.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KKK40497.1 - 0.0046 16.7 0.6 0.057 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KKK40497.1 - 0.0059 16.2 0.0 0.021 14.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KKK40497.1 - 0.0082 16.0 0.4 2.3 7.9 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK40497.1 - 0.039 13.8 0.1 0.069 13.0 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 KKK40499.1 - 3.1e-17 62.6 0.5 2.7e-16 59.5 0.5 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KKK40499.1 - 5.1e-08 32.5 2.5 2.4e-05 23.7 1.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KKK40499.1 - 1.8e-06 28.2 0.1 6.5e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK40499.1 - 2.9e-06 27.0 0.2 4.5e-06 26.3 0.2 1.5 1 1 0 1 1 1 1 Ras family ATP_bind_1 PF03029.17 KKK40499.1 - 1.4e-05 25.1 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KKK40499.1 - 5.4e-05 22.8 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KKK40499.1 - 5.7e-05 22.6 0.3 9.8e-05 21.8 0.3 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK40499.1 - 0.065 13.3 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK40499.1 - 0.16 12.3 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain TF_Zn_Ribbon PF08271.12 KKK40501.1 - 0.00023 20.6 1.3 0.00048 19.6 1.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2039 PF10217.9 KKK40501.1 - 0.066 13.6 0.1 0.24 11.7 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Zn-ribbon_8 PF09723.10 KKK40501.1 - 0.073 13.2 0.3 9.6 6.4 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK40501.1 - 0.077 12.9 0.3 0.21 11.6 0.3 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.7 KKK40501.1 - 0.13 12.3 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon YhfH PF14149.6 KKK40501.1 - 0.14 12.2 2.8 0.34 10.9 2.8 1.7 1 0 0 1 1 1 0 YhfH-like protein Hira PF07569.11 KKK40501.1 - 0.15 11.8 0.9 1.5 8.5 0.0 2.4 2 1 0 2 2 2 0 TUP1-like enhancer of split zf_Rg PF17915.1 KKK40501.1 - 0.25 10.8 1.9 0.72 9.3 1.9 1.7 1 0 0 1 1 1 0 Reverse gyrase zinc finger zf-CCCH_7 PF18586.1 KKK40501.1 - 0.3 11.5 1.8 1.6 9.2 0.6 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 A2L_zn_ribbon PF08792.10 KKK40501.1 - 4.9 7.0 6.0 78 3.2 6.1 2.6 1 1 1 2 2 2 0 A2L zinc ribbon domain Auto_anti-p27 PF06677.12 KKK40502.1 - 2.6e-12 46.7 0.1 3.8e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KKK40502.1 - 0.0041 17.1 0.7 0.0072 16.3 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon Ribosomal_L33 PF00471.20 KKK40502.1 - 0.0044 17.4 2.1 0.035 14.5 2.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L33 DNA_ligase_ZBD PF03119.16 KKK40502.1 - 0.0095 15.9 0.8 1 9.4 0.1 2.3 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain zinc-ribbons_6 PF07191.12 KKK40502.1 - 0.011 15.6 0.8 0.019 14.9 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF3802 PF12290.8 KKK40502.1 - 0.012 16.1 0.4 0.015 15.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) NOB1_Zn_bind PF08772.11 KKK40502.1 - 0.016 15.3 1.0 0.03 14.5 1.0 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like HAD_2 PF13419.6 KKK40502.1 - 0.031 14.4 0.7 0.035 14.2 0.7 1.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TF_Zn_Ribbon PF08271.12 KKK40502.1 - 0.043 13.3 2.3 0.043 13.3 2.3 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding zf-LITAF-like PF10601.9 KKK40502.1 - 0.056 13.7 1.9 1.2 9.5 2.0 2.2 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain zf-C3HC4_3 PF13920.6 KKK40502.1 - 0.084 12.7 0.9 0.15 11.9 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 KKK40502.1 - 0.11 12.2 7.5 0.99 9.2 7.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zf_UBZ PF18439.1 KKK40502.1 - 0.2 11.3 4.5 11 5.8 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 KKK40502.1 - 0.22 11.0 6.8 1.6 8.2 6.9 2.1 1 1 0 1 1 1 0 zinc-ribbon domain YacG PF03884.14 KKK40502.1 - 0.29 10.9 3.1 5.5 6.8 2.8 2.3 1 1 1 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_7 PF02591.15 KKK40502.1 - 0.33 11.2 2.2 3.2 8.0 0.1 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain RNA_POL_M_15KD PF02150.16 KKK40502.1 - 0.38 10.7 7.5 7.6 6.5 1.9 2.3 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_9 PF14369.6 KKK40502.1 - 0.4 11.0 6.2 4.4 7.6 0.5 2.3 1 1 1 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 KKK40502.1 - 0.51 10.5 3.4 22 5.3 0.2 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Rep_fac-A_C PF08646.10 KKK40502.1 - 0.85 9.4 6.3 0.52 10.1 2.3 2.1 1 1 1 2 2 2 0 Replication factor-A C terminal domain UPF0547 PF10571.9 KKK40502.1 - 3.7 7.7 6.3 12 6.0 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ribosomal_S17e PF00833.18 KKK40503.1 - 4e-15 55.8 1.1 4.2e-15 55.8 1.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 DUF4136 PF13590.6 KKK40504.1 - 0.12 13.0 0.4 0.3 11.7 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) AAA_22 PF13401.6 KKK40505.1 - 6.4e-10 39.4 0.2 2.2e-09 37.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.11 KKK40505.1 - 8.4e-09 35.3 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain TniB PF05621.11 KKK40505.1 - 1.5e-05 24.5 0.7 3.1e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 KKK40505.1 - 0.00013 22.4 0.1 0.0018 18.7 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KKK40505.1 - 0.00058 19.9 5.4 0.0012 18.8 5.4 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KKK40505.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KKK40505.1 - 0.027 14.9 0.3 0.078 13.4 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KKK40505.1 - 0.037 14.1 10.8 0.028 14.5 2.8 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 KKK40505.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KKK40505.1 - 0.079 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF853 PF05872.12 KKK40505.1 - 0.17 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.6 KKK40505.1 - 0.37 11.1 1.0 1.2 9.4 1.0 1.9 1 1 0 1 1 1 0 AAA domain HTH_5 PF01022.20 KKK40506.1 - 0.00016 21.5 1.4 0.00022 21.0 1.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TBPIP PF07106.13 KKK40506.1 - 0.00028 20.7 2.2 0.00048 20.0 0.6 2.0 1 1 1 2 2 2 1 TBPIP/Hop2 winged helix domain HTH_45 PF14947.6 KKK40506.1 - 0.0033 17.4 0.7 0.0058 16.6 0.7 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_20 PF12840.7 KKK40506.1 - 0.0068 16.4 0.0 0.0092 16.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 KKK40506.1 - 0.03 14.2 0.5 0.048 13.6 0.4 1.4 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 KKK40506.1 - 0.032 14.4 0.7 0.045 13.9 0.7 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_9 PF08221.11 KKK40506.1 - 0.044 13.9 0.9 0.064 13.4 0.9 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Peptidase_A24 PF01478.18 KKK40507.1 - 0.0048 17.3 13.8 0.0083 16.5 13.8 1.3 1 0 0 1 1 1 1 Type IV leader peptidase family Cyc-maltodext_N PF09087.11 KKK40508.1 - 0.029 14.6 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 Cyclomaltodextrinase, N-terminal COMM_domain PF07258.14 KKK40508.1 - 0.18 11.9 1.1 0.61 10.2 0.6 2.2 2 1 0 2 2 2 0 COMM domain V4R PF02830.18 KKK40509.1 - 0.00032 20.7 0.0 0.0006 19.8 0.0 1.5 1 0 0 1 1 1 1 V4R domain DUF4212 PF13937.6 KKK40510.1 - 5.4 7.5 15.8 1.9 8.9 1.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) SLED PF12140.8 KKK40511.1 - 0.12 12.9 2.4 0.27 11.8 0.7 2.4 2 0 0 2 2 2 0 SLED domain DUF3963 PF13124.6 KKK40512.1 - 0.016 15.2 0.1 0.065 13.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) T2SSE PF00437.20 KKK40513.1 - 2.2e-23 82.7 0.0 6.1e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KKK40513.1 - 0.0076 16.5 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK40513.1 - 0.02 14.6 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KKK40513.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK40513.1 - 0.062 13.4 0.5 0.33 11.0 0.0 2.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK40513.1 - 0.091 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain HypA PF01155.19 KKK40513.1 - 0.14 12.1 1.1 7.3 6.7 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Apo-CIII PF05778.12 KKK40513.1 - 0.18 11.5 2.8 0.52 10.0 2.8 1.7 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Ribosomal_L3 PF00297.22 KKK40514.1 - 1.6e-84 284.0 0.0 2e-84 283.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L4 PF00573.22 KKK40515.1 - 2.8e-27 95.6 0.1 3.8e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF2149 PF09919.9 KKK40515.1 - 0.076 13.3 0.8 0.19 12.0 0.7 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Ribosomal_L23 PF00276.20 KKK40516.1 - 3.5e-19 68.9 5.4 2.5e-18 66.2 5.4 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 Peroxin-22 PF12827.7 KKK40516.1 - 0.044 13.7 0.4 0.05 13.5 0.4 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Methyltransf_11 PF08241.12 KKK40518.1 - 5e-07 30.3 0.0 1e-06 29.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK40518.1 - 2.9e-06 27.9 0.0 6.6e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK40518.1 - 3.1e-05 23.8 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK40518.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK40518.1 - 0.0031 16.5 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KKK40518.1 - 0.022 15.5 0.0 0.06 14.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain tRNA-synt_1f PF01921.18 KKK40520.1 - 4.1e-93 312.2 1.3 6.2e-93 311.6 1.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) HypA PF01155.19 KKK40520.1 - 0.11 12.6 0.3 0.3 11.1 0.3 1.7 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2757 PF10955.8 KKK40520.1 - 0.8 10.0 5.9 2.2 8.6 1.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2757) ABC_tran PF00005.27 KKK40521.1 - 3.7e-42 144.1 1.0 1e-19 71.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KKK40521.1 - 7.1e-12 45.2 14.8 1.9e-07 30.7 1.2 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK40521.1 - 9.3e-10 38.8 16.1 0.0053 16.6 0.1 4.5 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKK40521.1 - 8.6e-07 29.0 0.5 0.0066 16.4 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 KKK40521.1 - 8.6e-07 29.5 0.0 0.039 14.3 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Septin PF00735.18 KKK40521.1 - 8.7e-07 28.5 0.1 0.00016 21.1 0.0 2.4 2 0 0 2 2 2 1 Septin RLI PF04068.15 KKK40521.1 - 2.3e-06 27.3 5.1 2.3e-06 27.3 5.1 2.2 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_23 PF13476.6 KKK40521.1 - 3e-06 27.9 12.8 0.0062 17.1 7.7 2.6 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KKK40521.1 - 6.8e-06 26.1 1.5 0.4 10.7 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KKK40521.1 - 8.1e-06 25.5 0.5 0.019 14.7 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4 PF00037.27 KKK40521.1 - 9.1e-06 25.3 0.4 9.1e-06 25.3 0.4 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain KAP_NTPase PF07693.14 KKK40521.1 - 1.1e-05 24.9 0.0 0.14 11.3 0.0 2.6 2 1 0 2 2 2 2 KAP family P-loop domain NB-ARC PF00931.22 KKK40521.1 - 2.2e-05 23.8 0.2 0.18 10.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 KKK40521.1 - 4.4e-05 23.8 0.1 0.33 11.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 KKK40521.1 - 7.4e-05 22.7 0.8 0.38 10.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 KKK40521.1 - 0.00016 21.7 0.1 0.99 9.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_24 PF13479.6 KKK40521.1 - 0.00017 21.4 1.2 0.35 10.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KKK40521.1 - 0.00017 21.9 0.0 0.7 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KKK40521.1 - 0.00023 21.6 0.1 0.13 12.7 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKK40521.1 - 0.0019 17.9 0.1 0.35 10.6 0.0 3.0 4 0 0 4 4 3 1 AAA domain NTPase_1 PF03266.15 KKK40521.1 - 0.0042 17.0 2.4 2.7 7.9 0.0 3.5 4 0 0 4 4 3 1 NTPase MeaB PF03308.16 KKK40521.1 - 0.007 15.4 0.4 0.15 11.0 0.0 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_6 PF12837.7 KKK40521.1 - 0.0088 16.1 0.2 0.0088 16.1 0.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain ATP_bind_1 PF03029.17 KKK40521.1 - 0.0092 15.8 0.1 8.6 6.1 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 KKK40521.1 - 0.0099 15.9 0.1 1.8 8.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 KKK40521.1 - 0.011 14.5 0.8 5 5.8 0.2 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 KKK40521.1 - 0.013 15.3 21.2 0.19 11.4 5.1 3.6 3 2 0 4 4 3 0 AAA ATPase domain AAA_33 PF13671.6 KKK40521.1 - 0.017 15.3 0.1 4.8 7.3 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_18 PF13238.6 KKK40521.1 - 0.026 15.1 0.5 4.3 7.9 0.0 3.4 2 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KKK40521.1 - 0.026 14.9 0.4 7.3 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KKK40521.1 - 0.033 14.4 1.1 6.8 6.9 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KKK40521.1 - 0.039 13.5 0.2 3.5 7.1 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 KKK40521.1 - 0.049 13.3 0.6 6.4 6.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 KKK40521.1 - 0.062 12.9 0.1 13 5.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Fer4_11 PF13247.6 KKK40521.1 - 0.083 13.0 2.3 0.14 12.2 2.3 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain MobB PF03205.14 KKK40521.1 - 0.089 12.7 2.4 7.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_7 PF12838.7 KKK40521.1 - 0.12 13.0 4.5 0.23 12.1 4.5 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF87 PF01935.17 KKK40521.1 - 0.14 12.3 6.9 1.3 9.1 0.1 3.6 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_28 PF13521.6 KKK40521.1 - 0.14 12.4 0.2 28 4.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_21 PF14697.6 KKK40521.1 - 0.3 11.2 4.4 0.54 10.4 4.4 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK40521.1 - 0.7 10.1 6.5 1.2 9.3 0.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain TrmB PF01978.19 KKK40522.1 - 3.9e-05 23.5 0.0 5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 KKK40522.1 - 0.00048 20.0 0.3 0.00094 19.1 0.3 1.6 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 KKK40522.1 - 0.0013 18.6 0.1 0.0019 18.1 0.1 1.2 1 0 0 1 1 1 1 MarR family DUF2250 PF10007.9 KKK40522.1 - 0.0026 17.8 0.1 0.0031 17.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_20 PF12840.7 KKK40522.1 - 0.0065 16.5 0.0 0.0087 16.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 KKK40522.1 - 0.0095 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_7 PF02796.15 KKK40522.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_9 PF08221.11 KKK40522.1 - 0.026 14.6 0.1 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain CENP-B_N PF04218.13 KKK40522.1 - 0.027 14.1 0.1 0.062 12.9 0.0 1.7 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain Replic_Relax PF13814.6 KKK40522.1 - 0.032 14.3 0.0 0.039 14.0 0.0 1.0 1 0 0 1 1 1 0 Replication-relaxation HTH_27 PF13463.6 KKK40522.1 - 0.099 13.2 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.7 KKK40522.1 - 0.17 11.8 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 MarR family NLE PF08154.12 KKK40523.1 - 0.044 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 NLE (NUC135) domain RHH_1 PF01402.21 KKK40523.1 - 0.048 13.6 0.3 2.7 8.0 0.0 2.6 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Saf_2TM PF18303.1 KKK40524.1 - 0.14 11.8 0.8 0.15 11.6 0.8 1.0 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain NIF3 PF01784.18 KKK40525.1 - 9.8e-41 140.0 0.2 1.3e-40 139.6 0.2 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Hexapep PF00132.24 KKK40526.1 - 5e-13 48.2 7.0 8.6e-06 25.3 0.0 4.4 3 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK40526.1 - 0.0065 16.2 8.6 0.72 9.7 0.1 3.9 4 2 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase MotB_plug PF13677.6 KKK40526.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB TFIIB PF00382.19 KKK40528.1 - 2.1e-29 101.4 0.1 5.2e-17 61.7 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.23 KKK40528.1 - 3.1e-07 30.2 0.6 0.0054 16.5 0.3 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.12 KKK40528.1 - 5e-07 29.1 1.3 1.1e-06 28.1 1.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KKK40528.1 - 0.00014 21.9 0.2 0.0061 16.6 0.1 2.3 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain HTH_24 PF13412.6 KKK40528.1 - 0.00028 20.4 0.7 0.018 14.6 0.0 2.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KKK40528.1 - 0.0021 18.4 0.1 3 8.3 0.0 2.3 2 0 0 2 2 2 2 Transcriptional regulator HTH_AsnC-type PF13404.6 KKK40528.1 - 0.0048 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 KKK40528.1 - 0.012 15.2 0.3 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Cyclin_C PF02984.19 KKK40528.1 - 0.023 14.8 0.0 5.6 7.1 0.0 2.3 1 1 0 2 2 2 0 Cyclin, C-terminal domain HTH_11 PF08279.12 KKK40528.1 - 0.024 14.6 0.8 0.065 13.2 0.1 2.1 2 0 0 2 2 2 0 HTH domain HTH_Crp_2 PF13545.6 KKK40528.1 - 0.026 14.5 0.1 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Anti-TRAP PF15777.5 KKK40528.1 - 0.055 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_Tnp_IS91 PF14319.6 KKK40528.1 - 0.061 13.4 0.9 0.15 12.1 0.2 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain HTH_Mga PF08280.11 KKK40528.1 - 0.074 13.1 1.6 0.34 11.0 0.1 2.6 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain A2L_zn_ribbon PF08792.10 KKK40528.1 - 0.12 12.1 1.2 0.31 10.8 1.2 1.7 1 0 0 1 1 1 0 A2L zinc ribbon domain HTH_Tnp_ISL3 PF13542.6 KKK40528.1 - 0.16 11.4 0.0 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 zf_UBZ PF18439.1 KKK40528.1 - 0.5 10.0 1.4 15 5.2 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Lar_restr_allev PF14354.6 KKK40528.1 - 0.7 10.3 3.7 0.66 10.4 0.4 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar AAA_18 PF13238.6 KKK40531.1 - 4.9e-26 91.8 0.1 1.5e-25 90.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKK40531.1 - 4.3e-05 23.9 0.0 0.00011 22.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KKK40531.1 - 4.9e-05 23.8 0.0 0.00011 22.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KKK40531.1 - 0.00027 20.7 0.0 0.21 11.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase TIP49 PF06068.13 KKK40531.1 - 0.00035 19.9 0.2 0.00078 18.7 0.1 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain Rad17 PF03215.15 KKK40531.1 - 0.00058 19.8 0.2 0.0012 18.8 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 KKK40531.1 - 0.0014 18.4 0.5 0.33 10.6 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 KKK40531.1 - 0.0017 18.3 2.8 0.46 10.3 0.1 2.4 1 1 0 2 2 2 2 Deoxynucleoside kinase RuvB_N PF05496.12 KKK40531.1 - 0.0038 17.0 0.1 0.0088 15.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 KKK40531.1 - 0.0038 17.4 0.1 0.18 11.9 0.0 2.3 2 1 0 2 2 2 1 Shikimate kinase RNA_helicase PF00910.22 KKK40531.1 - 0.0043 17.4 0.0 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KKK40531.1 - 0.0049 17.0 0.1 0.028 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK40531.1 - 0.0051 17.1 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KKK40531.1 - 0.0053 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 KKK40531.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 KKK40531.1 - 0.011 16.0 0.1 0.031 14.6 0.0 1.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain KTI12 PF08433.10 KKK40531.1 - 0.013 15.0 0.1 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 KKK40531.1 - 0.016 15.2 0.9 0.041 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK40531.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KKK40531.1 - 0.022 14.2 0.3 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 KKK40531.1 - 0.035 13.8 0.1 0.073 12.8 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KKK40531.1 - 0.036 13.2 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.6 KKK40531.1 - 0.052 13.7 0.1 0.17 12.0 0.1 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family PduV-EutP PF10662.9 KKK40531.1 - 0.078 12.7 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KKK40531.1 - 0.088 13.1 0.0 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain TGT PF01702.18 KKK40532.1 - 6.5e-61 206.4 0.0 8.8e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF5591 PF17884.1 KKK40532.1 - 1.1e-07 31.9 0.0 2.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5591) DUF371 PF04027.13 KKK40533.1 - 1.4e-45 154.5 0.1 1.7e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF371) Castor_Poll_mid PF06241.12 KKK40533.1 - 0.065 13.2 0.1 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Met_10 PF02475.16 KKK40534.1 - 1.1e-51 175.5 2.7 1.1e-51 175.5 2.7 1.5 2 0 0 2 2 2 1 Met-10+ like-protein PrmA PF06325.13 KKK40534.1 - 1.4e-07 31.2 0.1 3.1e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KKK40534.1 - 2.5e-05 23.9 0.0 5.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DNA_methylase PF00145.17 KKK40534.1 - 0.0013 18.1 0.5 0.0073 15.7 0.0 2.2 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 KKK40534.1 - 0.0024 17.5 0.3 0.0075 15.9 0.0 2.0 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KKK40534.1 - 0.0071 16.2 0.1 0.022 14.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KKK40534.1 - 0.014 15.1 0.0 0.069 12.8 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 KKK40534.1 - 0.051 13.2 0.0 0.26 10.9 0.0 2.1 2 1 1 3 3 3 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 KKK40534.1 - 0.069 13.9 0.0 0.16 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PDDEXK_1 PF12705.7 KKK40535.1 - 0.00024 21.1 0.1 0.0022 17.9 0.0 2.0 1 1 1 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF919 PF06034.11 KKK40535.1 - 1.6 8.6 6.9 0.32 10.9 2.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Aldose_epim PF01263.20 KKK40537.1 - 0.028 13.7 0.1 0.059 12.7 0.1 1.4 1 0 0 1 1 1 0 Aldose 1-epimerase TAFH PF07531.14 KKK40537.1 - 0.048 13.8 1.6 0.66 10.1 0.2 3.4 3 0 0 3 3 3 0 NHR1 homology to TAF PriA_3primeBD PF17764.1 KKK40537.1 - 0.73 9.8 3.5 18 5.3 0.1 3.4 3 0 0 3 3 3 0 3′ DNA-binding domain (3′BD) DUF4460 PF14687.6 KKK40538.1 - 0.0042 17.1 1.5 0.023 14.8 1.5 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) TEX12 PF15219.6 KKK40538.1 - 0.018 15.4 2.1 1.2 9.5 0.0 4.0 3 0 0 3 3 3 0 Testis-expressed 12 Robl_LC7 PF03259.17 KKK40539.1 - 0.0026 17.5 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain PALP PF00291.25 KKK40540.1 - 7.7e-40 137.1 0.0 1e-39 136.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CTP_transf_1 PF01148.20 KKK40541.1 - 0.0022 17.8 15.4 0.0022 17.8 15.4 2.4 1 1 1 2 2 2 1 Cytidylyltransferase family Phage_holin_3_3 PF16083.5 KKK40541.1 - 0.012 15.7 1.2 0.058 13.5 0.2 2.7 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III S_4TM PF18159.1 KKK40541.1 - 0.098 11.9 0.0 0.098 11.9 0.0 2.7 3 1 1 4 4 4 0 SMODS-associating 4TM effector domain PyrI PF01948.18 KKK40542.1 - 3.2e-26 91.4 9.3 6e-26 90.5 9.3 1.5 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 KKK40542.1 - 1.1e-13 50.8 7.1 1.5e-13 50.4 4.5 2.3 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF485 PF04341.12 KKK40543.1 - 0.016 15.1 7.5 0.026 14.5 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Peptidase_U4 PF03419.13 KKK40543.1 - 0.3 10.3 8.8 0.38 10.0 8.8 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2207 PF09972.9 KKK40543.1 - 0.73 8.5 10.8 2.1 7.0 10.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 KKK40543.1 - 3.1 7.9 5.3 4 7.5 5.3 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase FbpA PF05833.11 KKK40544.1 - 1e-58 199.2 29.0 1.4e-58 198.8 29.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KKK40544.1 - 5e-27 94.7 0.0 1e-26 93.7 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 KKK40544.1 - 0.00078 19.6 0.0 0.0039 17.4 0.0 2.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain Ribosomal_S13 PF00416.22 KKK40544.1 - 0.047 14.1 1.1 0.3 11.5 0.1 2.7 1 1 0 2 2 2 0 Ribosomal protein S13/S18 MatE PF01554.18 KKK40545.1 - 4e-05 23.3 1.3 4e-05 23.3 1.3 1.9 2 0 0 2 2 2 1 MatE CrgA PF06781.12 KKK40545.1 - 0.0047 16.9 4.0 0.037 14.1 0.4 2.2 2 0 0 2 2 2 2 Cell division protein CrgA DUF3975 PF13126.6 KKK40545.1 - 2.6 8.6 12.9 0.33 11.4 7.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3975) DUF4321 PF14209.6 KKK40546.1 - 1.9 8.4 17.2 0.24 11.3 6.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4321) MFS_1 PF07690.16 KKK40547.1 - 8.4e-07 28.2 8.7 8.4e-07 28.2 8.7 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Methyltransf_31 PF13847.6 KKK40548.1 - 1.1e-09 38.2 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK40548.1 - 5.9e-08 33.3 0.0 8.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK40548.1 - 1e-07 32.0 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK40548.1 - 1.4e-06 28.8 0.0 2.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK40548.1 - 5e-06 27.2 0.0 9.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK40548.1 - 2.2e-05 24.1 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KKK40548.1 - 6.2e-05 22.7 0.0 8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 KKK40548.1 - 0.0093 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 KKK40548.1 - 0.048 12.6 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Uricase PF01014.18 KKK40550.1 - 0.062 13.6 0.0 0.077 13.3 0.0 1.2 1 0 0 1 1 1 0 Uricase DUF3911 PF13050.6 KKK40550.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) RNase_P_Rpp14 PF01900.19 KKK40551.1 - 1.8e-19 69.9 0.1 2e-19 69.7 0.1 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family RNase_P_p30 PF01876.16 KKK40552.1 - 3.9e-11 42.8 5.9 4.9e-11 42.5 5.9 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Glyoxalase_4 PF13669.6 KKK40553.1 - 7.5e-14 51.9 0.1 9.6e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YonK PF09642.10 KKK40553.1 - 0.0058 16.8 1.5 0.0081 16.3 0.3 1.9 2 0 0 2 2 2 1 YonK protein Lig_C PF18330.1 KKK40553.1 - 0.069 13.1 1.0 0.11 12.6 0.4 1.6 2 0 0 2 2 2 0 Ligase Pab1020 C-terminal region LEDGF PF11467.8 KKK40553.1 - 0.27 10.9 2.1 0.38 10.4 0.4 1.9 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) TPP_enzyme_N PF02776.18 KKK40554.1 - 3.1e-53 179.9 0.0 2.6e-49 167.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKK40554.1 - 1.8e-40 138.3 0.0 1.2e-39 135.5 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK40554.1 - 6.4e-37 126.3 0.0 2.4e-36 124.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KKK40554.1 - 0.074 12.8 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit POR_N PF01855.19 KKK40554.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg adh_short_C2 PF13561.6 KKK40555.1 - 5.9e-57 192.9 0.0 6.8e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK40555.1 - 6.8e-46 156.2 0.1 8.6e-46 155.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK40555.1 - 4.5e-11 43.0 0.0 6.1e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK40555.1 - 0.0085 16.0 0.1 0.021 14.7 0.1 1.7 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KKK40555.1 - 0.035 13.6 0.0 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L15e PF00827.17 KKK40556.1 - 5.3e-71 238.3 10.1 5.9e-71 238.1 10.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 2-Hacid_dh_C PF02826.19 KKK40557.1 - 1.7e-54 183.9 0.0 2.5e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK40557.1 - 2.6e-30 104.8 0.1 2.9e-30 104.7 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK40557.1 - 8.3e-09 35.8 0.1 1.5e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KKK40557.1 - 0.0012 18.9 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 KKK40557.1 - 0.0035 17.4 0.9 0.081 13.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KKK40557.1 - 0.0039 16.5 0.0 0.01 15.1 0.0 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 KKK40557.1 - 0.0041 16.7 0.1 0.0073 15.9 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 KKK40557.1 - 0.0088 16.9 0.0 0.066 14.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.19 KKK40557.1 - 0.015 16.0 0.1 0.094 13.4 0.1 2.2 2 0 0 2 2 2 0 CoA binding domain F420_oxidored PF03807.17 KKK40557.1 - 0.016 15.8 0.1 0.045 14.3 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KKK40557.1 - 0.064 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2095 PF09868.9 KKK40558.1 - 2.3e-10 40.5 0.2 3.5e-10 39.9 0.2 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2095) SHOCT PF09851.9 KKK40558.1 - 0.15 11.9 0.6 0.39 10.5 0.6 1.8 1 0 0 1 1 1 0 Short C-terminal domain HTH_45 PF14947.6 KKK40559.1 - 9.8e-05 22.3 0.1 0.00013 21.9 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4894 PF16235.5 KKK40560.1 - 0.018 15.4 9.0 0.18 12.2 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4894) DUF3973 PF13119.6 KKK40560.1 - 0.19 11.8 0.5 0.84 9.8 0.5 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) HAD_2 PF13419.6 KKK40561.1 - 8.7e-23 81.3 7.1 8.7e-23 81.3 7.1 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK40561.1 - 7e-10 39.5 0.0 1.7e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK40561.1 - 8.9e-09 35.3 0.0 1.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 KKK40561.1 - 0.013 15.4 0.9 0.16 11.8 0.0 2.5 2 1 0 2 2 2 0 Acid Phosphatase PGP_phosphatase PF09419.10 KKK40561.1 - 0.013 15.1 0.3 0.029 14.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase CN_hydrolase PF00795.22 KKK40562.1 - 1.1e-25 90.5 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cdc6_C PF09079.11 KKK40563.1 - 0.024 14.6 0.3 0.093 12.7 0.2 2.0 1 1 1 2 2 2 0 CDC6, C terminal winged helix domain SMC_N PF02463.19 KKK40564.1 - 1.6e-42 145.4 99.1 6.4e-34 117.3 5.4 5.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KKK40564.1 - 1.4e-19 71.0 2.4 1.4e-19 71.0 2.4 6.2 1 1 5 6 6 6 1 AAA ATPase domain AAA_21 PF13304.6 KKK40564.1 - 1.5e-09 38.1 1.8 1.2e-05 25.3 0.1 7.1 4 2 4 8 8 8 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK40564.1 - 5.2e-06 26.1 0.1 1.1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 KKK40564.1 - 1 9.8 9.6 8.1 6.9 0.0 4.5 5 0 0 5 5 5 0 RNA helicase Mating_N PF12731.7 KKK40564.1 - 4.5 7.4 18.1 0.7 10.0 4.5 5.7 5 2 2 7 7 7 0 Mating-type protein beta 1 HeH PF12949.7 KKK40565.1 - 0.00095 18.8 0.5 0.00095 18.8 0.5 2.1 2 0 0 2 2 2 1 HeH/LEM domain Ish1 PF10281.9 KKK40565.1 - 0.0018 18.5 0.3 0.012 15.9 0.1 2.5 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein UPF0561 PF10573.9 KKK40565.1 - 7.8 6.7 8.8 3.9 7.6 0.2 2.8 2 1 0 3 3 3 0 Uncharacterised protein family UPF0561 Ribosomal_S15 PF00312.22 KKK40567.1 - 0.017 15.3 0.0 0.12 12.5 0.0 2.4 3 0 0 3 3 3 0 Ribosomal protein S15 Pox_F16 PF04708.12 KKK40567.1 - 0.026 14.0 0.5 0.026 14.0 0.5 2.6 3 1 0 3 3 3 0 Poxvirus F16 protein DUF2273 PF10031.9 KKK40568.1 - 0.9 9.6 28.1 1.5 8.9 14.9 2.8 2 1 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF2207 PF09972.9 KKK40568.1 - 1.6 7.4 4.4 1.6 7.4 4.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PTA_PTB PF01515.19 KKK40570.1 - 0.0014 18.0 0.1 0.005 16.2 0.0 1.8 2 1 1 3 3 3 1 Phosphate acetyl/butaryl transferase CPBP PF02517.16 KKK40571.1 - 5.4e-13 49.1 6.9 5.4e-13 49.1 6.9 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DZR PF12773.7 KKK40571.1 - 0.00065 19.7 0.1 0.0011 19.0 0.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK40571.1 - 0.0025 17.5 4.3 0.0049 16.5 4.3 1.5 1 1 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK40571.1 - 0.067 12.6 1.9 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.12 KKK40571.1 - 0.077 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Nudix_N_2 PF14803.6 KKK40571.1 - 0.38 10.7 1.5 17 5.4 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal Cys_rich_KTR PF14205.6 KKK40571.1 - 0.61 9.9 3.8 2 8.3 3.8 1.9 1 1 0 1 1 1 0 Cysteine-rich KTR RNA_POL_M_15KD PF02150.16 KKK40571.1 - 1.8 8.5 5.6 12 5.9 0.4 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Transglut_C PF00927.22 KKK40572.1 - 0.14 12.4 1.2 0.77 9.9 0.1 2.6 2 2 1 3 3 3 0 Transglutaminase family, C-terminal ig like domain DUF2393 PF09624.10 KKK40572.1 - 0.42 10.6 5.5 0.096 12.7 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) CCG PF02754.16 KKK40576.1 - 1.6e-19 69.9 2.0 8.3e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 Cysteine-rich domain NLRC4_HD PF17889.1 KKK40576.1 - 0.091 13.1 0.1 6.8 7.1 0.0 2.8 3 0 0 3 3 3 0 NLRC4 helical domain HATPase_c PF02518.26 KKK40577.1 - 3.6e-14 53.2 2.2 4.1e-13 49.8 0.4 2.7 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 KKK40577.1 - 6.8e-06 26.2 0.1 1.4e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 KKK40577.1 - 0.00037 21.1 0.0 0.00081 20.0 0.0 1.6 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KKK40577.1 - 0.0004 20.4 0.1 0.0011 19.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 KKK40577.1 - 0.00062 19.7 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.6 KKK40577.1 - 0.00095 19.5 0.0 0.0029 17.9 0.0 1.8 2 0 0 2 2 2 1 GAF domain HATPase_c_5 PF14501.6 KKK40577.1 - 0.0056 16.6 11.6 0.11 12.4 6.2 3.5 2 1 0 2 2 2 1 GHKL domain PAS PF00989.25 KKK40577.1 - 0.0082 16.1 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 KKK40577.1 - 0.024 14.6 0.0 1.1 9.2 0.0 2.4 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain SPG48 PF14764.6 KKK40577.1 - 0.035 14.6 0.3 0.13 12.7 0.1 2.0 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking PAS_4 PF08448.10 KKK40577.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 PAS fold Thioredoxin_3 PF13192.6 KKK40578.1 - 8.4e-20 70.6 0.3 3.2e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin PF00085.20 KKK40578.1 - 5.6e-13 48.8 0.1 2.2e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KKK40578.1 - 6.8e-09 36.1 1.2 0.0021 18.5 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Glutaredoxin PF00462.24 KKK40578.1 - 1.5e-07 31.5 0.2 5.3e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 KKK40578.1 - 6.2e-07 29.7 0.0 0.056 13.9 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.6 KKK40578.1 - 7.9e-07 28.9 0.9 0.0047 16.7 0.3 2.7 2 1 0 2 2 2 2 Thioredoxin TraF PF13728.6 KKK40578.1 - 1.7e-05 24.7 0.0 0.018 14.9 0.0 2.4 2 1 0 2 2 2 2 F plasmid transfer operon protein ABC_transp_aux PF09822.9 KKK40578.1 - 9e-05 22.1 0.2 0.0068 15.9 0.2 2.1 1 1 1 2 2 2 1 ABC-type uncharacterized transport system TrbC_Ftype PF09673.10 KKK40578.1 - 0.0026 17.8 0.2 0.33 11.0 0.0 2.8 2 1 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein Thioredoxin_8 PF13905.6 KKK40578.1 - 0.0041 17.4 0.7 0.15 12.4 0.2 3.1 2 2 1 3 3 3 1 Thioredoxin-like DSBA PF01323.20 KKK40578.1 - 0.0052 16.6 0.2 0.36 10.6 0.0 2.8 2 1 1 3 3 3 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 KKK40578.1 - 0.025 14.2 0.0 6.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DUF1525 PF07511.11 KKK40578.1 - 0.075 13.2 0.0 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) DUF334 PF03904.13 KKK40578.1 - 0.078 12.5 2.9 0.11 12.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) HyaE PF07449.11 KKK40578.1 - 0.082 12.9 0.0 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE zf-TFIIB PF13453.6 KKK40578.1 - 0.1 12.0 0.5 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger Thioredoxin_3 PF13192.6 KKK40579.1 - 2.8e-16 59.3 0.9 4.8e-10 39.4 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin PF00085.20 KKK40579.1 - 1e-09 38.3 0.1 0.0002 21.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KKK40579.1 - 7.5e-09 36.0 2.3 0.00076 19.9 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KKK40579.1 - 7.1e-07 29.1 0.3 0.00013 21.7 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin DUF836 PF05768.14 KKK40579.1 - 4.5e-05 23.8 0.0 0.34 11.4 0.0 2.2 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KKK40579.1 - 7.4e-05 22.9 0.3 0.041 14.1 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin ABC_transp_aux PF09822.9 KKK40579.1 - 0.0025 17.3 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 ABC-type uncharacterized transport system TraF PF13728.6 KKK40579.1 - 0.0065 16.3 0.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 1 F plasmid transfer operon protein TrbC_Ftype PF09673.10 KKK40579.1 - 0.15 12.1 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Pyr_redox_2 PF07992.14 KKK40580.1 - 2e-42 145.4 0.6 2.5e-42 145.1 0.6 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK40580.1 - 2.9e-25 89.1 7.1 2e-23 83.1 0.8 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK40580.1 - 3.9e-14 53.0 4.3 2e-10 41.0 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK40580.1 - 0.00011 21.7 0.1 0.01 15.2 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK40580.1 - 0.00011 21.4 0.3 0.073 12.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 KKK40580.1 - 0.00027 21.4 0.2 0.0047 17.4 0.3 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 KKK40580.1 - 0.053 12.2 3.4 1.4 7.6 0.5 3.1 4 0 0 4 4 4 0 HI0933-like protein GIDA PF01134.22 KKK40580.1 - 0.13 11.3 3.5 1.7 7.7 0.1 2.6 2 1 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KKK40580.1 - 0.17 11.0 0.2 13 4.8 0.0 2.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) GAF_2 PF13185.6 KKK40581.1 - 1.7e-13 51.0 0.0 2.8e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KKK40581.1 - 4.8e-05 24.0 0.0 9.4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 GAF domain DUF724 PF05266.14 KKK40581.1 - 0.00031 20.6 2.9 0.00069 19.5 2.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF724) AsnC_trans_reg PF01037.21 KKK40581.1 - 0.013 15.4 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain GAF_3 PF13492.6 KKK40581.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.6 1 1 0 1 1 1 0 GAF domain SpoVT_C PF15714.5 KKK40581.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor Nsp1_C PF05064.13 KKK40581.1 - 0.057 13.2 2.0 0.06 13.2 0.3 1.9 2 0 0 2 2 2 0 Nsp1-like C-terminal region TFIIB PF00382.19 KKK40582.1 - 5.8e-21 74.3 0.0 1.6e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KKK40582.1 - 7.7e-06 25.3 0.9 1.4e-05 24.5 0.9 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_3 PF01381.22 KKK40582.1 - 0.0019 18.3 0.1 0.0064 16.5 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix RB_B PF01857.20 KKK40582.1 - 0.0083 16.2 1.7 0.021 14.9 0.6 2.3 2 1 0 2 2 2 1 Retinoblastoma-associated protein B domain HTH_24 PF13412.6 KKK40582.1 - 0.011 15.3 0.2 0.72 9.5 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 KKK40582.1 - 0.068 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DZR PF12773.7 KKK40582.1 - 0.085 12.9 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon PriA_CRR PF18319.1 KKK40582.1 - 0.1 12.6 0.4 0.1 12.6 0.4 1.9 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Sigma70_r4_2 PF08281.12 KKK40582.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 KKK40583.1 - 2.8e-12 46.0 0.1 6.7e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK40583.1 - 5.7e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 KKK40583.1 - 2.5e-05 24.1 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 KKK40583.1 - 3e-05 23.8 0.0 6.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 KKK40583.1 - 0.00052 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 KKK40583.1 - 0.00079 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 KKK40583.1 - 0.0025 17.8 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 KKK40583.1 - 0.0042 16.9 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_1 PF00126.27 KKK40583.1 - 0.049 13.6 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family AsnC_trans_reg PF01037.21 KKK40583.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Fe_dep_repress PF01325.19 KKK40583.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 KKK40583.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_IclR PF09339.10 KKK40583.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.7 KKK40583.1 - 0.08 13.0 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_36 PF13730.6 KKK40583.1 - 0.087 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TbpB_C PF17483.2 KKK40584.1 - 0.029 14.7 0.1 0.031 14.6 0.1 1.2 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B DUF4184 PF13803.6 KKK40585.1 - 2e-06 27.7 7.3 2e-06 27.7 7.3 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4184) YdjM PF04307.14 KKK40585.1 - 5.2e-05 22.6 7.6 0.00013 21.4 7.6 1.6 1 1 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase Zn_dep_PLPC PF00882.18 KKK40585.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 1 0 1 1 1 1 Zinc dependent phospholipase C adh_short_C2 PF13561.6 KKK40586.1 - 5.1e-62 209.5 0.0 6.2e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK40586.1 - 1.2e-43 148.9 0.1 1.5e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK40586.1 - 9.3e-06 25.7 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK40586.1 - 0.0097 15.4 0.0 0.012 15.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KKK40586.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fer4_9 PF13187.6 KKK40587.1 - 1.1e-06 28.7 10.5 1.3e-06 28.4 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40587.1 - 4.8e-05 23.2 16.3 0.016 15.2 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 KKK40587.1 - 8.2e-05 22.2 10.4 0.0015 18.3 1.6 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK40587.1 - 0.0011 19.1 14.5 0.0014 18.7 14.5 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK40587.1 - 0.002 18.7 14.4 0.071 13.7 3.6 2.2 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40587.1 - 0.028 14.5 17.5 0.033 14.3 2.1 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 KKK40587.1 - 1.2 9.3 18.2 6.6 6.9 18.4 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK40587.1 - 3.7 8.3 19.5 1.5 9.5 3.5 2.7 3 0 0 3 3 3 0 4Fe-4S binding domain PolC_DP2 PF03833.13 KKK40587.1 - 4.5 5.0 9.6 4.3 5.1 9.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Fer4_8 PF13183.6 KKK40587.1 - 8.8 6.9 16.6 10 6.7 2.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain SfsA PF03749.13 KKK40588.1 - 2.7e-29 101.8 0.0 4e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 KKK40588.1 - 4.4e-18 65.2 0.0 8.1e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 SfsA N-terminal OB domain HTH_24 PF13412.6 KKK40589.1 - 5.6e-14 51.4 0.4 7.4e-14 51.0 0.4 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK40589.1 - 2e-12 46.7 0.1 2.7e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 KKK40589.1 - 1e-06 28.6 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 KKK40589.1 - 3.1e-06 26.9 0.0 4.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KKK40589.1 - 6.7e-05 22.7 0.0 7.7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.16 KKK40589.1 - 0.00013 21.4 0.1 0.00022 20.7 0.1 1.4 1 1 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 KKK40589.1 - 0.00089 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 KKK40589.1 - 0.0015 18.4 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 KKK40589.1 - 0.0022 18.0 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KKK40589.1 - 0.0025 17.8 0.0 0.003 17.5 0.0 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 KKK40589.1 - 0.0045 17.2 0.2 0.0058 16.9 0.2 1.2 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 KKK40589.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain Rrf2 PF02082.20 KKK40589.1 - 0.018 15.4 0.1 0.024 15.0 0.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator HTH_1 PF00126.27 KKK40589.1 - 0.028 14.4 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Fe_dep_repress PF01325.19 KKK40589.1 - 0.037 14.2 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 KKK40589.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain F420_oxidored PF03807.17 KKK40593.1 - 2e-22 79.6 0.6 3.1e-22 79.0 0.2 1.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KKK40593.1 - 9.8e-08 32.3 0.3 2e-07 31.3 0.3 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KKK40593.1 - 0.00013 21.9 1.9 0.0062 16.5 1.9 2.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KKK40593.1 - 0.0032 17.4 0.1 0.0048 16.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KKK40593.1 - 0.0099 15.7 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.12 KKK40593.1 - 0.028 14.0 0.1 0.042 13.4 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Gp_dh_N PF00044.24 KKK40593.1 - 0.053 13.9 0.5 0.15 12.4 0.5 1.7 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KKK40593.1 - 0.062 12.9 0.3 0.22 11.1 0.1 2.0 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK40593.1 - 0.084 12.2 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK40593.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1028 PF06267.12 KKK40594.1 - 4.1e-69 232.2 0.0 5.1e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF1028) TPR_2 PF07719.17 KKK40594.1 - 6.1e-08 32.2 0.8 0.0012 18.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK40594.1 - 0.00012 21.8 1.3 0.044 13.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK40594.1 - 0.00023 21.6 0.0 0.00067 20.1 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK40594.1 - 0.00031 20.4 0.1 0.00095 18.8 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 KKK40594.1 - 0.0014 19.2 0.0 0.63 11.0 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK40594.1 - 0.0077 16.4 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK40594.1 - 0.0082 16.8 0.0 0.19 12.4 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK40594.1 - 0.029 14.6 0.4 0.66 10.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKK40594.1 - 0.058 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 KKK40595.1 - 7e-30 103.7 0.0 5.3e-29 100.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK40595.1 - 5.8e-27 93.7 1.2 1.2e-26 92.7 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KKK40595.1 - 1.4e-11 44.3 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK40595.1 - 1.1e-07 33.0 0.0 1.6e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.13 KKK40595.1 - 7e-05 22.4 0.3 0.00011 21.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AlaDh_PNT_C PF01262.21 KKK40595.1 - 9.3e-05 21.8 0.7 0.00015 21.1 0.7 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.7 KKK40595.1 - 0.00023 21.1 0.3 0.00042 20.3 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK40595.1 - 0.00027 21.6 0.1 0.00062 20.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain CoA_binding PF02629.19 KKK40595.1 - 0.0012 19.5 0.3 0.0026 18.4 0.3 1.6 1 0 0 1 1 1 1 CoA binding domain Methyltransf_31 PF13847.6 KKK40595.1 - 0.0013 18.6 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK40595.1 - 0.0032 18.2 0.1 0.0086 16.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 KKK40595.1 - 0.0054 17.0 1.7 0.0091 16.3 0.9 1.8 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 KKK40595.1 - 0.027 14.5 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ubie_methyltran PF01209.18 KKK40595.1 - 0.031 13.6 0.1 0.079 12.3 0.1 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KKK40595.1 - 0.037 13.6 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain OCD_Mu_crystall PF02423.15 KKK40595.1 - 0.039 12.9 0.3 0.075 11.9 0.2 1.4 1 1 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family FtsX PF02687.21 KKK40596.1 - 1.8e-14 54.0 22.8 3.4e-10 40.2 8.1 5.5 7 0 0 7 7 7 2 FtsX-like permease family ABC_tran PF00005.27 KKK40597.1 - 2.2e-27 96.2 0.0 3.2e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK40597.1 - 2.4e-07 30.8 0.5 0.0012 18.7 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK40597.1 - 4.2e-05 23.1 0.0 0.00024 20.6 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK40597.1 - 4.9e-05 23.3 0.2 8.2e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KKK40597.1 - 0.0059 15.7 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 KKK40597.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KKK40597.1 - 0.0062 16.5 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 KKK40597.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK40597.1 - 0.0064 17.0 0.6 0.016 15.8 0.6 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK40597.1 - 0.01 16.2 0.1 0.014 15.8 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KKK40597.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 KKK40597.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Arf PF00025.21 KKK40597.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 KKK40597.1 - 0.026 15.1 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK40597.1 - 0.027 14.7 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KKK40597.1 - 0.04 13.1 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 KKK40597.1 - 0.043 14.1 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK40597.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KKK40597.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KKK40597.1 - 0.078 13.2 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KKK40597.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KKK40598.1 - 0.0022 17.0 14.6 0.0027 16.7 14.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily LAB_N PF07578.11 KKK40598.1 - 0.1 12.7 0.8 0.1 12.7 0.8 2.7 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain DUF3177 PF11375.8 KKK40598.1 - 1.6 8.5 14.4 0.16 11.8 9.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3177) DeoC PF01791.9 KKK40599.1 - 6.2e-16 58.7 0.0 8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase AbiJ_NTD4 PF18863.1 KKK40600.1 - 0.043 14.3 4.6 0.068 13.6 4.6 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 Peptidase_M28 PF04389.17 KKK40601.1 - 6.8e-26 91.2 0.0 2.1e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 DUF4910 PF16254.5 KKK40601.1 - 0.017 14.0 0.6 0.39 9.6 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4910) CMV_US PF08001.11 KKK40601.1 - 0.17 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 CMV US Phage_holin_3_6 PF07332.11 KKK40601.1 - 1.6 8.8 12.8 2.5 8.2 0.2 2.5 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 KKK40601.1 - 5.4 5.7 16.1 3.8 6.2 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) CPBP PF02517.16 KKK40602.1 - 6.6e-18 64.9 5.3 6.6e-18 64.9 5.3 6.5 4 2 0 4 4 4 2 CPBP intramembrane metalloprotease 12TM_1 PF09847.9 KKK40602.1 - 1e-08 34.8 79.2 1e-08 34.8 79.2 3.1 3 1 0 3 3 3 1 Membrane protein of 12 TMs ABC_tran PF00005.27 KKK40603.1 - 1.8e-30 106.2 0.0 3.8e-30 105.2 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KKK40603.1 - 1.1e-10 41.9 4.5 1.8e-05 24.7 0.7 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK40603.1 - 4.6e-05 24.0 2.6 8.4e-05 23.2 2.6 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KKK40603.1 - 0.00062 19.7 0.7 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 NTPase AAA_30 PF13604.6 KKK40603.1 - 0.0046 16.7 0.0 0.024 14.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK40603.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK40603.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK40603.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KKK40603.1 - 0.2 12.1 1.2 0.57 10.6 0.4 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KKK40603.1 - 0.22 11.0 0.5 11 5.4 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 KKK40604.1 - 2.2e-05 24.1 4.2 2.2e-05 24.1 4.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 KKK40604.1 - 6.4e-05 23.8 6.2 6.4e-05 23.8 6.2 2.2 2 2 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK40604.1 - 0.00045 20.7 6.4 0.00077 20.0 5.4 2.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK40604.1 - 0.00069 19.7 1.5 0.00069 19.7 1.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40604.1 - 0.011 15.7 3.7 0.011 15.7 3.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 KKK40604.1 - 0.015 15.7 4.8 0.017 15.5 0.4 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK40604.1 - 0.049 13.8 8.7 0.15 12.2 8.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK40604.1 - 1 10.5 11.9 0.3 12.1 6.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK40604.1 - 1.6 9.4 11.1 0.1 13.1 3.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40604.1 - 3 8.1 11.6 0.53 10.5 3.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ABC_tran PF00005.27 KKK40605.1 - 2.6e-27 96.0 0.0 3.6e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK40605.1 - 6e-11 42.7 0.1 2.8e-07 30.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 KKK40605.1 - 1.9e-05 23.5 0.9 0.0076 14.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KKK40605.1 - 4.7e-05 23.3 0.0 0.042 13.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK40605.1 - 0.0096 15.8 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 KKK40605.1 - 0.019 15.4 0.8 0.22 11.9 0.8 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KKK40605.1 - 0.032 14.0 0.2 0.082 12.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KKK40605.1 - 0.054 12.9 0.3 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATP_bind_1 PF03029.17 KKK40605.1 - 0.069 12.9 0.5 0.34 10.7 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KKK40605.1 - 0.097 13.2 2.1 0.15 12.6 2.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK40605.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KKK40605.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KKK40605.1 - 0.13 11.9 0.3 0.23 11.1 0.3 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KKK40605.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane PF01061.24 KKK40606.1 - 0.0014 18.1 16.6 0.0014 18.1 16.6 4.0 3 1 0 3 3 3 1 ABC-2 type transporter TNFR_16_TM PF18422.1 KKK40606.1 - 2.5 8.1 7.4 0.52 10.3 0.4 3.4 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain FrhB_FdhB_C PF04432.13 KKK40607.1 - 1.7e-36 125.4 0.1 3.5e-36 124.4 0.1 1.5 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK40607.1 - 2.4e-09 37.2 0.0 5.7e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term DHODB_Fe-S_bind PF10418.9 KKK40607.1 - 5.3e-09 35.7 5.4 5.3e-09 35.7 5.4 3.1 3 0 0 3 3 3 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NAD_binding_1 PF00175.21 KKK40607.1 - 2.4e-05 24.9 0.0 5.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKK40607.1 - 0.012 15.9 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKK40607.1 - 0.11 12.6 0.7 2.3 8.3 0.2 2.7 1 1 1 2 2 2 0 Ferric reductase NAD binding domain POR PF01558.18 KKK40608.1 - 2.7e-08 34.1 0.1 3.5e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TrbC PF04956.13 KKK40608.1 - 0.08 13.2 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family Gtr1_RagA PF04670.12 KKK40609.1 - 2e-20 73.1 2.0 3.3e-20 72.5 2.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK40609.1 - 2e-06 27.4 0.3 4.3e-06 26.3 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK40609.1 - 0.00059 19.4 0.2 0.06 12.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KKK40609.1 - 0.001 19.5 1.6 0.0074 16.7 0.8 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 KKK40609.1 - 0.0028 17.2 0.1 0.0073 15.9 0.1 1.8 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KKK40609.1 - 0.0033 17.3 0.1 0.53 10.2 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KKK40609.1 - 0.0072 16.4 0.0 0.024 14.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KKK40609.1 - 0.02 15.1 0.2 0.068 13.4 0.2 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ribonuc_2-5A PF06479.12 KKK40609.1 - 0.026 14.7 0.3 0.069 13.3 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease 2-5A DUF815 PF05673.13 KKK40609.1 - 0.027 13.7 0.2 0.14 11.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KKK40609.1 - 0.03 14.9 0.1 0.063 13.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 KKK40609.1 - 0.069 12.9 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK40609.1 - 0.15 12.4 0.1 0.34 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain ADH_zinc_N PF00107.26 KKK40611.1 - 4e-34 117.4 0.1 6.7e-34 116.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK40611.1 - 8.3e-25 88.4 0.0 4.4e-24 86.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK40611.1 - 8.5e-20 70.7 0.1 2.5e-19 69.2 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KKK40611.1 - 0.0016 17.8 0.1 0.0025 17.2 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KKK40611.1 - 0.035 14.4 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HasA PF06438.12 KKK40611.1 - 0.043 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Heme-binding protein A (HasA) PALP PF00291.25 KKK40611.1 - 0.045 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Hydrolase_4 PF12146.8 KKK40612.1 - 6.3e-05 22.4 0.0 0.00086 18.6 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK40612.1 - 0.00053 19.7 0.2 0.012 15.3 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK40612.1 - 0.0097 16.5 0.0 0.01 16.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KKK40612.1 - 0.027 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family QRPTase_C PF01729.19 KKK40613.1 - 1.1e-43 149.0 0.3 1.6e-43 148.4 0.3 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KKK40613.1 - 1.5e-21 76.2 0.0 3.1e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain RHH_1 PF01402.21 KKK40614.1 - 0.00017 21.4 0.1 0.00037 20.3 0.1 1.6 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family NikR_C PF08753.11 KKK40614.1 - 0.00086 19.4 0.2 0.0015 18.6 0.2 1.4 1 0 0 1 1 1 1 NikR C terminal nickel binding domain baeRF_family2 PF18844.1 KKK40614.1 - 0.19 11.8 0.0 0.61 10.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Aldolase_II PF00596.21 KKK40615.1 - 2.8e-41 141.5 0.1 3.3e-41 141.3 0.1 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain IMS PF00817.20 KKK40616.1 - 4.1e-44 150.2 0.0 2.7e-43 147.5 0.0 2.2 2 1 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KKK40616.1 - 5e-15 56.2 0.3 9.7e-15 55.3 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKK40616.1 - 6.5e-05 23.0 1.0 0.0002 21.5 0.0 2.5 3 0 0 3 3 3 1 IMS family HHH motif AMP-binding_C_2 PF14535.6 KKK40616.1 - 0.048 14.0 0.7 0.17 12.2 0.1 2.2 2 2 0 2 2 2 0 AMP-binding enzyme C-terminal domain HHH_5 PF14520.6 KKK40616.1 - 0.14 12.8 0.1 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Occludin_ELL PF07303.13 KKK40616.1 - 1 10.1 5.3 16 6.3 0.1 3.2 2 1 1 3 3 3 0 Occludin homology domain AMMECR1 PF01871.17 KKK40617.1 - 4.3e-45 153.3 0.0 4.8e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DUF2247 PF10004.9 KKK40617.1 - 0.058 13.2 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Amidohydro_1 PF01979.20 KKK40618.1 - 4.8e-20 72.2 0.0 9.5e-20 71.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK40618.1 - 2e-08 34.2 0.0 0.00098 18.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Vesiculo_matrix PF06326.12 KKK40618.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Vesiculovirus matrix protein Methyltrn_RNA_2 PF04013.12 KKK40619.1 - 5.4e-08 32.8 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Putative SAM-dependent RNA methyltransferase T3RM_EcoP15I_C PF18273.1 KKK40619.1 - 0.096 13.0 0.4 0.096 13.0 0.4 2.4 2 1 0 3 3 3 0 Type III R-M EcoP15I C-terminal domain MerR PF00376.23 KKK40623.1 - 0.018 14.8 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 MerR family regulatory protein HTH_23 PF13384.6 KKK40623.1 - 0.027 14.3 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4 PF04545.16 KKK40623.1 - 0.027 14.0 0.4 0.11 12.0 0.2 2.1 1 1 1 2 2 2 0 Sigma-70, region 4 HTH_17 PF12728.7 KKK40623.1 - 0.031 14.4 0.4 0.077 13.2 0.1 1.7 2 1 0 2 2 2 0 Helix-turn-helix domain Phage_integrase PF00589.22 KKK40624.1 - 1.2e-09 38.1 0.7 1.2e-09 38.1 0.7 1.8 2 0 0 2 2 2 1 Phage integrase family DUF4763 PF15960.5 KKK40624.1 - 0.00088 18.7 1.3 0.00088 18.7 1.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) CIDE-N PF02017.15 KKK40624.1 - 0.13 12.3 1.4 0.64 10.1 0.1 2.6 2 0 0 2 2 2 0 CIDE-N domain GIT_CC PF16559.5 KKK40624.1 - 1.6 8.6 7.1 0.57 10.1 1.7 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor PIG-P PF08510.12 KKK40625.1 - 0.019 14.9 0.5 0.019 14.9 0.5 1.9 2 0 0 2 2 2 0 PIG-P DUF4271 PF14093.6 KKK40625.1 - 0.47 10.3 21.7 5.7 6.8 19.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) MacB_PCD PF12704.7 KKK40625.1 - 8.5 6.7 5.8 17 5.7 5.8 1.5 1 0 0 1 1 1 0 MacB-like periplasmic core domain FAM150 PF15129.6 KKK40626.1 - 0.047 13.8 0.2 0.093 12.9 0.2 1.4 1 0 0 1 1 1 0 FAM150 family RNR_Alpha PF17975.1 KKK40627.1 - 5.1e-36 123.2 0.0 1.8e-35 121.5 0.0 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Intein_splicing PF14890.6 KKK40627.1 - 6e-23 81.3 0.0 2.7e-10 40.3 0.0 2.9 2 1 0 2 2 2 2 Intein splicing domain LAGLIDADG_3 PF14528.6 KKK40627.1 - 1.1e-13 51.3 0.0 3.8e-08 33.5 0.0 3.3 3 0 0 3 3 3 2 LAGLIDADG-like domain HNH_3 PF13392.6 KKK40627.1 - 1.3e-06 28.0 0.1 2.9e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Ribonuc_red_lgC PF02867.15 KKK40627.1 - 1.1e-05 24.2 1.1 0.099 11.2 0.0 3.3 3 0 0 3 3 3 2 Ribonucleotide reductase, barrel domain Hint_2 PF13403.6 KKK40627.1 - 0.00011 22.5 0.1 0.00064 20.1 0.0 2.2 2 0 0 2 2 2 1 Hint domain Hom_end PF05204.14 KKK40627.1 - 0.001 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Homing endonuclease Vint PF14623.6 KKK40627.1 - 0.014 15.2 0.0 0.81 9.5 0.0 2.6 2 0 0 2 2 2 0 Hint-domain PT-HINT PF07591.11 KKK40627.1 - 0.093 13.0 4.1 13 6.0 0.1 4.1 4 0 0 4 4 4 0 Pretoxin HINT domain ATP-cone PF03477.16 KKK40627.1 - 0.35 11.5 4.2 0.22 12.1 0.3 2.7 3 0 0 3 3 3 0 ATP cone domain Polbeta PF18765.1 KKK40628.1 - 1.1e-21 76.7 0.7 1.5e-21 76.2 0.7 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK40628.1 - 6.1e-08 32.8 0.4 1.1e-07 32.0 0.4 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain DUF3870 PF12986.7 KKK40628.1 - 0.027 14.7 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Peptidase_M28 PF04389.17 KKK40628.1 - 0.097 12.4 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M28 Methyltransf_11 PF08241.12 KKK40630.1 - 1.6e-23 83.1 0.0 3e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK40630.1 - 5.6e-20 71.8 0.0 1.1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK40630.1 - 1.2e-17 64.2 0.0 1.4e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK40630.1 - 1.8e-15 57.2 0.0 2.7e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK40630.1 - 4.1e-15 55.7 0.0 1.8e-13 50.3 0.0 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK40630.1 - 4.6e-15 56.2 0.0 1.2e-14 54.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 KKK40630.1 - 1e-12 48.0 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KKK40630.1 - 1.1e-06 28.3 0.6 3.9e-06 26.6 0.5 1.8 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 KKK40630.1 - 2.6e-06 26.9 0.0 4.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 KKK40630.1 - 3.6e-05 23.8 0.0 6.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK40630.1 - 0.00048 19.2 0.0 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 KKK40630.1 - 0.00069 19.4 0.2 0.0061 16.3 0.1 2.0 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 KKK40630.1 - 0.0042 16.6 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 KKK40630.1 - 0.0097 15.3 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 KKK40630.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 KKK40630.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 KKK40630.1 - 0.023 13.3 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase JMY PF15871.5 KKK40630.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein UPF0020 PF01170.18 KKK40630.1 - 0.035 13.8 0.0 0.084 12.5 0.0 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 CagD PF16567.5 KKK40630.1 - 0.057 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Pathogenicity island component CagD NodS PF05401.11 KKK40630.1 - 0.06 13.0 0.0 0.21 11.2 0.0 1.7 1 1 1 2 2 2 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 KKK40630.1 - 0.072 12.9 0.1 0.24 11.2 0.1 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.13 KKK40630.1 - 0.087 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KKK40630.1 - 0.097 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.12 KKK40630.1 - 0.12 11.4 0.0 0.87 8.6 0.0 2.0 1 1 1 2 2 2 0 DREV methyltransferase AA_permease_C PF13906.6 KKK40632.1 - 9.5e-05 22.4 6.3 9.5e-05 22.4 6.3 2.1 2 1 0 2 2 2 1 C-terminus of AA_permease DUF86 PF01934.17 KKK40633.1 - 9e-09 35.2 0.4 1.2e-08 34.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF86 Pex24p PF06398.11 KKK40634.1 - 0.4 9.6 1.8 0.67 8.9 1.8 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin PALP PF00291.25 KKK40635.1 - 0.005 16.3 0.0 0.0058 16.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hexapep PF00132.24 KKK40636.1 - 1.2e-05 24.9 2.6 0.00093 18.8 1.1 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK40636.1 - 0.005 16.6 6.8 0.17 11.7 1.6 3.1 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase SP24 PF16504.5 KKK40636.1 - 0.28 11.2 5.2 0.2 11.7 3.0 1.9 2 0 0 2 2 2 0 Putative virion membrane protein of plant and insect virus Hexapep PF00132.24 KKK40637.1 - 2.2e-06 27.2 1.0 0.00091 18.9 0.4 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DHHC PF01529.20 KKK40638.1 - 3.8 7.6 13.4 5.5 7.1 13.4 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase CBFD_NFYB_HMF PF00808.23 KKK40642.1 - 4.7e-06 26.8 0.0 5.8e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Flavi_NS2A PF01005.19 KKK40642.1 - 0.04 14.1 0.0 0.045 13.9 0.0 1.0 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A Proteasome PF00227.26 KKK40643.1 - 1.2e-47 161.8 0.6 1.4e-47 161.7 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-RING_2 PF13639.6 KKK40644.1 - 0.00038 20.7 8.4 0.00062 20.0 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KKK40644.1 - 0.00059 20.1 5.6 0.0012 19.1 5.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 KKK40644.1 - 0.004 17.0 9.5 0.046 13.7 9.8 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 DIT1_PvcA PF05141.12 KKK40644.1 - 0.005 16.3 0.8 0.005 16.3 0.8 2.2 3 0 0 3 3 3 1 Pyoverdine/dityrosine biosynthesis protein PHD PF00628.29 KKK40644.1 - 0.0071 16.2 7.3 0.012 15.4 7.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING_9 PF13901.6 KKK40644.1 - 0.016 15.2 3.0 0.016 15.2 3.0 2.9 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon DUF1451 PF07295.11 KKK40644.1 - 0.029 14.4 7.5 0.15 12.1 0.1 4.3 3 1 1 4 4 4 0 Zinc-ribbon containing domain DUF948 PF06103.11 KKK40644.1 - 0.06 13.6 3.5 13 6.1 0.2 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HSBP1 PF06825.12 KKK40644.1 - 0.065 13.1 5.7 33 4.4 0.1 5.7 6 0 0 6 6 6 0 Heat shock factor binding protein 1 COMMD1_N PF17221.3 KKK40644.1 - 0.072 13.4 5.6 0.14 12.5 0.0 3.2 3 0 0 3 3 3 0 COMMD1 N-terminal domain Prok-RING_4 PF14447.6 KKK40644.1 - 0.087 12.7 7.5 0.79 9.6 0.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF4743 PF15916.5 KKK40644.1 - 0.097 12.6 0.2 0.3 11.0 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) P22_AR_C PF10548.9 KKK40644.1 - 0.1 12.8 0.9 1.3 9.3 0.0 3.4 3 1 0 3 3 2 0 P22AR C-terminal domain zf-C3HC4_2 PF13923.6 KKK40644.1 - 0.11 12.3 8.8 0.2 11.5 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UBZ_FAAP20 PF15750.5 KKK40644.1 - 0.12 12.4 2.5 0.35 10.9 0.4 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger ImpE PF07024.13 KKK40644.1 - 0.17 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 ImpE protein zinc_ribbon_9 PF14369.6 KKK40644.1 - 0.18 12.1 2.9 11 6.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon DUF4347 PF14252.6 KKK40644.1 - 0.23 11.3 2.0 8.5 6.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) zf-C3HC4_3 PF13920.6 KKK40644.1 - 0.37 10.7 6.4 0.63 9.9 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK40644.1 - 0.73 9.5 7.1 1.2 8.8 7.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-CHCC PF10276.9 KKK40644.1 - 0.99 9.5 3.6 0.63 10.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain L31 PF09784.9 KKK40644.1 - 1.4 9.4 5.0 4.8 7.7 0.0 3.4 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 A2L_zn_ribbon PF08792.10 KKK40644.1 - 1.4 8.7 8.3 0.11 12.2 2.6 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.22 KKK40644.1 - 2.1 8.3 8.1 0.4 10.6 3.9 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KKK40644.1 - 2.5 8.3 5.0 6 7.0 5.0 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.8 KKK40644.1 - 4.6 7.5 7.4 14 5.9 7.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain LysE PF01810.18 KKK40645.1 - 1.7e-28 99.4 11.2 2.1e-28 99.1 11.2 1.1 1 0 0 1 1 1 1 LysE type translocator US10 PF17617.2 KKK40645.1 - 1.6 8.8 5.1 1.8 8.6 0.5 2.1 2 0 0 2 2 2 0 Viral unique short region 10 RE_HindIII PF09518.10 KKK40646.1 - 0.013 14.7 5.0 0.016 14.5 5.0 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease DUF3671 PF12420.8 KKK40646.1 - 0.027 14.5 2.2 0.027 14.5 2.2 2.4 2 2 1 3 3 3 0 Protein of unknown function Prominin PF05478.11 KKK40646.1 - 0.049 11.6 0.0 0.055 11.4 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF4349 PF14257.6 KKK40646.1 - 0.084 12.3 0.3 0.2 11.0 0.0 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) DUF3899 PF13038.6 KKK40646.1 - 0.088 13.3 0.1 0.088 13.3 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3899) Kinesin_assoc PF16183.5 KKK40646.1 - 5.2 7.2 6.7 7.2 6.7 0.8 2.1 1 1 1 2 2 2 0 Kinesin-associated Aminotran_1_2 PF00155.21 KKK40647.1 - 2.7e-32 112.3 0.0 3.9e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK40647.1 - 0.047 12.6 0.0 0.084 11.8 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V EF1_GNE PF00736.19 KKK40647.1 - 0.073 13.2 0.3 4.5 7.5 0.1 2.9 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain DUF2175 PF09943.9 KKK40647.1 - 0.091 13.1 1.6 17 5.7 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) HGD-D PF06050.13 KKK40647.1 - 0.12 12.2 0.1 16 5.1 0.0 2.1 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component YkyA PF10368.9 KKK40647.1 - 0.19 11.4 5.7 3.1 7.4 0.1 2.6 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Gelsolin PF00626.22 KKK40648.1 - 3.8e-26 90.8 0.1 1.8e-15 56.6 0.0 2.4 2 0 0 2 2 2 2 Gelsolin repeat Adenylate_cycl PF01295.18 KKK40648.1 - 0.22 10.1 0.0 7.9 5.0 0.0 2.1 2 0 0 2 2 2 0 Adenylate cyclase, class-I DUF1786 PF08735.10 KKK40649.1 - 0.38 10.0 3.5 0.13 11.5 0.2 1.9 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) DUF745 PF05335.13 KKK40649.1 - 6.8 6.4 25.9 3.8 7.2 2.4 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF745) GtrA PF04138.14 KKK40650.1 - 6.8e-13 48.9 9.8 1.4e-12 47.9 3.3 2.5 1 1 1 2 2 2 2 GtrA-like protein IBV_3A PF03617.13 KKK40650.1 - 0.064 13.2 0.9 0.18 11.8 0.9 1.7 1 0 0 1 1 1 0 IBV 3A protein Phage_holin_3_1 PF05106.12 KKK40650.1 - 0.14 12.6 2.8 2.8 8.4 0.7 2.4 1 1 1 2 2 2 0 Phage holin family (Lysis protein S) 2TM PF13239.6 KKK40650.1 - 9 6.7 7.9 2.2 8.6 4.1 2.0 1 1 1 2 2 2 0 2TM domain EMC3_TMCO1 PF01956.16 KKK40651.1 - 0.00022 21.0 14.3 0.0005 19.8 13.7 2.0 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like 60KD_IMP PF02096.20 KKK40651.1 - 0.042 13.8 8.4 0.067 13.1 8.4 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein UPF0370 PF13980.6 KKK40651.1 - 1.1 9.3 3.7 2 8.5 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Radical_SAM PF04055.21 KKK40652.1 - 2e-21 77.1 0.0 4.8e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK40652.1 - 5.8e-08 33.1 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK40652.1 - 0.0003 20.9 0.0 0.00078 19.6 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 KKK40652.1 - 0.00036 21.0 1.3 0.0036 17.8 0.4 2.5 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain ECH_1 PF00378.20 KKK40657.1 - 6.3e-45 153.5 0.3 4.2e-43 147.5 0.3 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK40657.1 - 2.3e-22 80.0 0.2 8.3e-16 58.4 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Baculo_PEP_C PF04513.12 KKK40658.1 - 0.048 13.7 0.2 0.098 12.7 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Viral_DNA_bp PF00747.17 KKK40658.1 - 0.059 10.5 0.1 0.081 10.1 0.1 1.1 1 0 0 1 1 1 0 ssDNA binding protein eIF-4B PF06273.11 KKK40658.1 - 0.2 10.7 6.7 0.32 10.0 6.7 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Pyr_redox_2 PF07992.14 KKK40659.1 - 1e-35 123.5 0.2 2.1e-35 122.4 0.1 1.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK40659.1 - 1.2e-14 54.6 0.5 2.1e-14 53.8 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK40659.1 - 4.3e-09 36.1 0.2 6.3e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KKK40659.1 - 4e-08 33.0 0.0 1.5e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain HI0933_like PF03486.14 KKK40659.1 - 0.0033 16.2 0.8 0.02 13.6 0.1 2.0 1 1 1 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 KKK40659.1 - 0.015 15.7 0.1 0.029 14.8 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 KKK40659.1 - 0.11 11.6 0.6 0.29 10.2 0.3 1.8 1 1 1 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KKK40659.1 - 0.11 12.5 0.0 1.1 9.2 0.0 2.1 1 1 1 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 KKK40659.1 - 0.15 11.6 0.0 0.5 9.9 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK40659.1 - 0.17 10.9 0.0 0.5 9.4 0.0 1.7 1 1 1 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 KKK40659.1 - 0.26 10.5 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Flavodoxin_5 PF12724.7 KKK40660.1 - 2e-12 47.6 0.1 2.4e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 KKK40660.1 - 1e-07 32.2 0.1 1.4e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 KKK40660.1 - 2.4e-07 30.6 0.3 3.1e-07 30.2 0.3 1.2 1 0 0 1 1 1 1 Flavodoxin domain NRDD PF13597.6 KKK40660.1 - 0.002 17.0 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase NMT1 PF09084.11 KKK40660.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like CmcI PF04989.12 KKK40660.1 - 0.017 14.9 0.3 0.029 14.0 0.3 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase Hemerythrin PF01814.23 KKK40662.1 - 2.1e-10 41.3 2.7 4.4e-10 40.3 1.5 2.1 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF1858 PF08984.11 KKK40662.1 - 0.0025 17.9 0.2 0.0097 16.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1858) CdiA_C_tRNase PF18664.1 KKK40662.1 - 0.0073 16.5 1.5 0.02 15.1 1.2 1.8 1 1 1 2 2 2 1 CdiA C-terminal tRNase domain HetR_C PF18460.1 KKK40662.1 - 0.011 15.7 1.6 0.25 11.3 0.1 2.7 1 1 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Inhibitor_I29 PF08246.12 KKK40662.1 - 0.069 13.6 1.6 0.17 12.4 1.6 1.7 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Nitroreductase PF00881.24 KKK40663.1 - 1.6e-21 77.1 0.0 2e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family CN_hydrolase PF00795.22 KKK40664.1 - 2.1e-27 96.1 0.0 2.5e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CN_hydrolase PF00795.22 KKK40665.1 - 0.0012 18.2 0.1 0.0013 18.2 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FUR PF01475.19 KKK40666.1 - 0.00036 20.7 0.6 0.0015 18.7 0.0 2.3 2 1 0 2 2 2 1 Ferric uptake regulator family HTH_34 PF13601.6 KKK40666.1 - 0.0022 18.1 0.1 0.005 17.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MCPsignal PF00015.21 KKK40667.1 - 5.1e-32 111.0 19.0 5.8e-32 110.9 9.8 2.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PhageMin_Tail PF10145.9 KKK40667.1 - 0.0014 18.5 4.6 0.0014 18.5 4.6 1.6 1 1 0 1 1 1 1 Phage-related minor tail protein Med9 PF07544.13 KKK40667.1 - 0.12 12.5 0.7 0.22 11.6 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GLYCAM-1 PF05242.11 KKK40667.1 - 0.15 12.2 6.3 0.08 13.1 4.1 1.6 1 1 1 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF3739 PF12545.8 KKK40667.1 - 0.25 11.8 1.2 0.55 10.7 1.2 1.6 1 0 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein DUF948 PF06103.11 KKK40667.1 - 0.46 10.8 13.0 6.3 7.1 0.1 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) I_LWEQ PF01608.17 KKK40667.1 - 0.49 10.6 6.9 0.56 10.4 5.5 1.7 1 1 1 2 2 2 0 I/LWEQ domain TMEM220 PF15071.6 KKK40667.1 - 0.5 11.2 6.7 0.18 12.6 0.8 2.8 1 1 1 2 2 2 0 Transmembrane family 220, helix Response_reg PF00072.24 KKK40668.1 - 1.4e-22 80.0 2.0 1.8e-22 79.6 1.1 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Dam PF05869.11 KKK40668.1 - 0.0095 15.5 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) Tautomerase PF01361.21 KKK40669.1 - 4.2e-13 49.0 0.1 4.4e-13 48.9 0.1 1.0 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 KKK40669.1 - 0.011 15.8 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Tautomerase enzyme DSBA PF01323.20 KKK40670.1 - 9.3e-41 139.7 0.0 1e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KKK40670.1 - 3.2e-11 43.7 0.0 2.5e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin COMPASS-Shg1 PF05205.12 KKK40670.1 - 0.01 16.5 0.1 0.018 15.7 0.1 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 UBA_2 PF08587.11 KKK40670.1 - 0.011 15.8 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Radical_SAM PF04055.21 KKK40670.1 - 0.12 12.8 0.0 0.26 11.6 0.0 1.7 1 1 0 1 1 1 0 Radical SAM superfamily Thioredoxin_5 PF13743.6 KKK40670.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin Abhydrolase_1 PF00561.20 KKK40671.1 - 7.9e-07 29.0 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK40671.1 - 1.1e-05 24.8 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK40671.1 - 0.00016 22.3 0.0 0.00048 20.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Alba PF01918.21 KKK40671.1 - 0.051 13.4 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 Alba Ras PF00071.22 KKK40672.1 - 9.7e-40 135.8 0.0 1.1e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40672.1 - 7.6e-25 87.5 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40672.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK40672.1 - 0.0024 17.3 0.0 0.0032 16.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 KKK40672.1 - 0.036 14.0 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KKK40672.1 - 0.05 13.9 0.0 4.8 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KKK40672.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ZnuA PF01297.17 KKK40672.1 - 0.12 11.7 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic BrkDBD PF09607.10 KKK40672.1 - 0.17 11.7 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Brinker DNA-binding domain Adenine_glyco PF03352.13 KKK40673.1 - 3.4e-24 85.6 0.5 1.1e-23 83.9 0.3 1.7 1 1 1 2 2 2 1 Methyladenine glycosylase SelR PF01641.18 KKK40674.1 - 3.5e-54 182.0 1.3 4.1e-54 181.8 1.3 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 KKK40674.1 - 0.0016 18.4 0.5 0.24 11.4 0.2 2.2 2 0 0 2 2 2 1 Double zinc ribbon zf-C2HC5 PF06221.13 KKK40674.1 - 0.0032 17.4 2.3 2 8.5 0.0 2.4 2 1 0 2 2 2 2 Putative zinc finger motif, C2HC5-type Yippee-Mis18 PF03226.14 KKK40674.1 - 0.0097 16.1 1.3 0.034 14.4 1.2 2.0 1 1 1 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.14 KKK40674.1 - 0.028 14.8 2.7 4 7.8 0.6 2.4 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_10 PF10058.9 KKK40674.1 - 0.041 13.6 2.8 2.3 8.0 0.4 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Di19 PF05605.12 KKK40674.1 - 0.043 14.1 1.1 0.13 12.6 1.1 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-Mss51 PF13824.6 KKK40674.1 - 0.1 12.7 1.3 0.41 10.8 0.1 2.3 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_ribbon_recom PF13408.6 KKK40674.1 - 0.17 12.4 4.2 1.4 9.5 0.1 2.8 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.6 KKK40674.1 - 4.2 6.9 7.3 8.3 6.0 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK40674.1 - 5.2 6.9 9.6 5.3 6.9 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain PMSR PF01625.21 KKK40675.1 - 2.4e-09 37.6 0.2 2.5e-09 37.5 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase RNase_H_2 PF13482.6 KKK40678.1 - 5.7e-06 26.4 0.7 1.3e-05 25.3 0.1 1.8 2 0 0 2 2 2 1 RNase_H superfamily Thiolase_N PF00108.23 KKK40679.1 - 9e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK40679.1 - 0.0077 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain OB_aCoA_assoc PF01796.17 KKK40680.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 KKK40680.1 - 0.17 11.8 0.1 27 4.8 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NiFeSe_Hases PF00374.19 KKK40681.1 - 1.8e-45 155.8 0.1 6.9e-25 87.9 0.0 3.1 2 1 0 3 3 3 3 Nickel-dependent hydrogenase Oxidored_q6 PF01058.22 KKK40682.1 - 3.3e-28 98.1 0.7 5.7e-28 97.4 0.7 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit FlpD PF02662.16 KKK40683.1 - 9e-36 122.6 0.3 1.3e-34 118.8 0.0 2.8 3 0 0 3 3 3 1 Methyl-viologen-reducing hydrogenase, delta subunit Pyr_redox_2 PF07992.14 KKK40683.1 - 1.6e-09 37.5 0.1 0.00024 20.4 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.27 KKK40683.1 - 2.7e-07 30.1 3.4 2.7e-07 30.1 3.4 5.3 6 0 0 6 6 5 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK40683.1 - 4.3e-07 30.4 29.5 4.1e-05 24.1 10.5 4.3 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40683.1 - 1.4e-06 28.1 3.2 1.4e-06 28.1 3.2 5.3 5 0 0 5 5 5 1 4Fe-4S binding domain Fer4_9 PF13187.6 KKK40683.1 - 3.5e-06 27.1 26.4 0.00078 19.6 9.8 3.4 3 1 0 3 3 2 2 4Fe-4S dicluster domain FAD_oxidored PF12831.7 KKK40683.1 - 1.2e-05 24.9 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK40683.1 - 0.0001 21.5 0.1 0.00015 21.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK40683.1 - 0.00013 22.2 0.1 0.00028 21.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK40683.1 - 0.0009 19.7 0.0 0.0037 17.8 0.0 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.6 KKK40683.1 - 0.0011 19.0 3.0 0.0011 19.0 3.0 4.4 3 1 1 4 4 4 3 4Fe-4S dicluster domain DAO PF01266.24 KKK40683.1 - 0.0018 18.0 0.2 0.0039 16.8 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_2 PF12797.7 KKK40683.1 - 0.0027 17.7 4.6 0.0027 17.7 4.6 5.7 6 0 0 6 6 6 2 4Fe-4S binding domain GIDA PF01134.22 KKK40683.1 - 0.012 14.7 0.0 0.03 13.4 0.0 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KKK40683.1 - 0.014 14.1 0.0 0.029 13.1 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Fer4_16 PF13484.6 KKK40683.1 - 0.024 15.6 0.3 0.024 15.6 0.3 4.7 3 1 1 4 4 4 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK40683.1 - 0.026 15.0 3.1 0.026 15.0 3.1 5.1 5 0 0 5 5 3 0 4Fe-4S binding domain Pyr_redox_3 PF13738.6 KKK40683.1 - 0.048 12.9 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK40683.1 - 0.22 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Fer4_21 PF14697.6 KKK40683.1 - 0.38 10.9 29.6 0.021 15.0 9.5 4.2 5 0 0 5 5 4 0 4Fe-4S dicluster domain BKACE PF05853.12 KKK40685.1 - 1e-41 143.1 0.0 1.1e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme BKACE PF05853.12 KKK40686.1 - 1.1e-28 100.3 0.0 1.2e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme DHO_dh PF01180.21 KKK40688.1 - 1.8e-06 27.4 0.0 1.9e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Nop PF01798.18 KKK40689.1 - 1.9e-55 187.8 0.6 2.4e-55 187.5 0.1 1.4 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Fibrillarin PF01269.17 KKK40690.1 - 1.1e-73 247.1 0.2 1.2e-73 246.9 0.2 1.0 1 0 0 1 1 1 1 Fibrillarin FAD_binding_2 PF00890.24 KKK40692.1 - 2e-22 79.9 0.3 2.2e-22 79.8 0.3 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK40692.1 - 0.00054 19.7 0.1 0.00054 19.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK40692.1 - 0.0068 15.7 0.1 0.0081 15.4 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KKK40692.1 - 0.016 14.5 0.1 0.018 14.3 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KKK40692.1 - 0.13 12.6 0.3 0.14 12.4 0.3 1.4 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2204 PF09970.9 KKK40694.1 - 0.00072 19.2 0.7 0.0013 18.4 0.7 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) PsbQ PF05757.11 KKK40694.1 - 0.019 14.7 1.0 0.027 14.2 1.0 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) FERM_F1 PF18379.1 KKK40694.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain NdhM PF10664.9 KKK40694.1 - 0.11 12.7 1.8 0.49 10.7 0.1 2.6 1 1 2 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M UPF0175 PF03683.13 KKK40695.1 - 3.5e-06 26.6 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) HTH_psq PF05225.16 KKK40695.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF3368 PF11848.8 KKK40696.1 - 4.6e-05 23.1 0.3 0.0001 22.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3368) PIN PF01850.21 KKK40696.1 - 0.0028 18.1 1.5 0.0046 17.5 0.1 1.8 2 0 0 2 2 2 1 PIN domain TPP_enzyme_C PF02775.21 KKK40697.1 - 3.9e-30 104.7 1.0 5.6e-30 104.1 1.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 KKK40697.1 - 5.1e-21 74.6 1.5 9.7e-21 73.7 1.5 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal G3P_antiterm PF04309.12 KKK40697.1 - 0.056 12.9 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF4116 PF13475.6 KKK40697.1 - 0.091 12.5 0.2 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) POR_N PF01855.19 KKK40698.1 - 1.7e-52 178.4 0.0 2.3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KKK40698.1 - 7.3e-28 97.8 0.0 1.2e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_N PF02776.18 KKK40698.1 - 0.088 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Nitroreductase PF00881.24 KKK40699.1 - 4.9e-27 95.0 0.0 6.7e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK40699.1 - 1.6e-07 31.1 4.4 0.0018 17.8 0.2 3.0 1 1 2 3 3 3 2 Putative TM nitroreductase Fer4_7 PF12838.7 KKK40699.1 - 4.2e-05 24.0 3.8 0.05 14.2 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK40699.1 - 0.00015 21.9 10.5 0.00024 21.2 10.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK40699.1 - 0.00033 21.5 3.6 0.16 12.9 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK40699.1 - 0.0016 18.5 10.3 0.0032 17.5 10.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK40699.1 - 0.0059 16.7 9.5 0.012 15.8 9.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK40699.1 - 0.0095 15.7 16.4 0.01 15.6 3.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 KKK40699.1 - 0.031 15.0 6.7 0.21 12.3 0.7 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_6 PF12837.7 KKK40699.1 - 0.036 14.2 14.2 0.47 10.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK40699.1 - 0.91 9.7 7.6 0.92 9.7 0.1 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40699.1 - 1.2 9.3 11.5 0.12 12.6 1.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain CxC7 PF18866.1 KKK40699.1 - 1.7 8.8 5.7 3.5 7.8 5.7 1.4 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases Polbeta PF18765.1 KKK40700.1 - 1.8e-16 60.0 1.8 2.6e-16 59.5 1.8 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK40700.1 - 0.00022 21.5 0.6 0.00033 20.9 0.6 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain MFS_2 PF13347.6 KKK40701.1 - 1.9e-37 128.9 41.8 2.2e-37 128.7 41.8 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KKK40701.1 - 2.1e-08 33.5 44.3 1.4e-07 30.8 14.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_3 PF07969.11 KKK40702.1 - 3.1e-27 96.2 0.0 2.3e-26 93.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KKK40702.1 - 1.2e-11 44.6 0.0 0.00023 20.6 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 KKK40702.1 - 0.086 13.2 0.9 0.26 11.6 0.9 1.8 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Aminotran_3 PF00202.21 KKK40706.1 - 1.5e-38 132.5 0.0 2.4e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III HHH_5 PF14520.6 KKK40707.1 - 1e-12 48.5 0.4 1.9e-12 47.6 0.4 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KKK40707.1 - 6.4e-07 29.4 0.1 8.1e-05 22.7 0.0 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 KKK40707.1 - 1.6e-06 27.8 0.0 1e-05 25.3 0.0 2.1 1 1 1 2 2 2 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 KKK40707.1 - 1.3e-05 25.3 0.0 0.00025 21.2 0.0 2.2 2 0 0 2 2 2 1 Pathogenicity locus HHH PF00633.23 KKK40707.1 - 1.5e-05 24.6 0.1 0.039 13.8 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif DUF4332 PF14229.6 KKK40707.1 - 6.2e-05 23.2 0.0 0.00015 22.0 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4332) HHH_3 PF12836.7 KKK40707.1 - 0.001 19.3 0.1 0.36 11.1 0.0 2.3 1 1 1 2 2 2 1 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 KKK40707.1 - 0.0051 16.5 0.1 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH_8 PF14716.6 KKK40707.1 - 0.0053 17.1 0.5 2.2 8.7 0.1 3.0 2 1 1 3 3 3 1 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 KKK40707.1 - 0.0079 16.8 0.7 4.9 7.8 0.2 2.2 1 1 1 2 2 2 2 5'-3' exonuclease, C-terminal SAM fold Nitro_FeMo-Co PF02579.17 KKK40707.1 - 0.017 15.4 0.8 0.44 10.9 0.0 2.4 2 1 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor zf-C4_Topoisom PF01396.19 KKK40707.1 - 0.026 14.3 0.2 0.052 13.3 0.2 1.5 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger FdhE PF04216.12 KKK40707.1 - 0.03 14.2 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf_Rg PF17915.1 KKK40707.1 - 0.031 13.7 1.4 0.068 12.6 1.4 1.7 1 1 0 1 1 1 0 Reverse gyrase zinc finger Zn-ribbon_8 PF09723.10 KKK40707.1 - 0.035 14.2 0.7 0.054 13.6 0.0 1.6 2 0 0 2 2 2 0 Zinc ribbon domain DUF1272 PF06906.11 KKK40707.1 - 0.059 13.5 0.7 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) BAF PF02961.14 KKK40707.1 - 0.067 13.6 0.1 3.9 8.0 0.0 2.3 1 1 1 2 2 2 0 Barrier to autointegration factor YhfH PF14149.6 KKK40707.1 - 0.19 11.8 4.0 2.5 8.2 0.2 2.4 2 0 0 2 2 2 0 YhfH-like protein EMP70 PF02990.16 KKK40708.1 - 2 7.0 20.3 0.042 12.5 2.6 2.1 1 1 0 2 2 2 0 Endomembrane protein 70 BRI3BP PF14965.6 KKK40709.1 - 0.32 10.5 4.0 0.58 9.6 4.0 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 PRIMA1 PF16101.5 KKK40709.1 - 2.1 8.4 3.2 17 5.5 0.1 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 EamA PF00892.20 KKK40711.1 - 2.9e-35 121.4 46.7 4.5e-20 72.2 18.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 KKK40711.1 - 1.2 9.0 48.9 0.16 11.8 2.5 3.1 1 1 2 3 3 3 0 7TM diverse intracellular signalling YrhC PF14143.6 KKK40712.1 - 2.4 8.3 9.1 4.1 7.6 0.1 3.7 3 0 0 3 3 3 0 YrhC-like protein MRF_C1 PF13887.6 KKK40713.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 ApoB100_C PF12491.8 KKK40713.1 - 0.054 13.5 0.8 0.071 13.1 0.8 1.3 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal HATPase_c PF02518.26 KKK40714.1 - 3.9e-18 66.0 0.1 4.4e-18 65.8 0.1 1.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK40714.1 - 6.6e-06 26.0 0.8 9.6e-06 25.4 0.8 1.2 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KKK40714.1 - 0.0022 17.9 0.0 0.0029 17.6 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Radical_SAM PF04055.21 KKK40719.1 - 3.1e-19 70.0 0.2 5.3e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK40719.1 - 3.1e-08 34.0 0.1 3.1e-08 34.0 0.1 2.5 3 0 0 3 3 3 1 4Fe-4S single cluster domain SPASM PF13186.6 KKK40719.1 - 8.8e-08 32.6 2.7 8.8e-08 32.6 2.7 2.4 2 1 0 2 2 2 1 Iron-sulfur cluster-binding domain Fer4_14 PF13394.6 KKK40719.1 - 0.00094 19.3 0.1 0.00094 19.3 0.1 2.4 3 0 0 3 3 3 1 4Fe-4S single cluster domain Aminotran_5 PF00266.19 KKK40720.1 - 9.5e-79 265.0 2.6 1e-58 199.1 0.5 3.3 3 1 0 3 3 3 3 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK40720.1 - 7.6e-05 22.0 0.2 0.00021 20.6 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK40720.1 - 0.0088 15.4 0.0 0.022 14.0 0.0 1.8 1 0 0 1 1 1 1 Beta-eliminating lyase IMPDH PF00478.25 KKK40720.1 - 0.013 14.6 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Cys_Met_Meta_PP PF01053.20 KKK40720.1 - 0.016 13.7 0.0 0.16 10.5 0.0 2.2 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 KKK40720.1 - 0.078 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KKK40720.1 - 0.081 12.2 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2626 PF11117.8 KKK40720.1 - 0.099 13.4 0.1 0.25 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2626) PhzC-PhzF PF02567.16 KKK40721.1 - 1.4e-59 201.9 0.0 1.5e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein SnoaL PF07366.12 KKK40722.1 - 0.033 14.0 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL PF07366.12 KKK40723.1 - 7.7e-05 22.5 0.1 7.9e-05 22.5 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF1848 PF08902.11 KKK40724.1 - 1.3e-63 215.2 8.4 1.5e-63 215.0 8.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1848) Radical_SAM PF04055.21 KKK40724.1 - 0.02 15.3 2.3 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Radical SAM superfamily UbiA PF01040.18 KKK40725.1 - 2.2e-32 112.3 16.7 3e-32 111.9 16.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2244 PF10003.9 KKK40725.1 - 3.3 7.4 8.7 38 3.9 0.1 2.6 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4458 PF14660.6 KKK40726.1 - 0.073 13.3 0.5 1.3 9.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4458) IF-2B PF01008.17 KKK40727.1 - 4.4e-67 226.3 1.2 5.2e-67 226.0 1.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Glyco_hydro_4 PF02056.16 KKK40730.1 - 1.3e-43 148.7 0.0 3.7e-43 147.2 0.0 1.7 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase Glyco_hydro_4C PF11975.8 KKK40730.1 - 1.9e-41 142.4 0.0 2.7e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain BOFC_N PF08977.10 KKK40731.1 - 0.033 14.2 0.2 0.039 13.9 0.2 1.1 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal Swi3 PF07962.12 KKK40731.1 - 0.066 13.2 0.1 0.071 13.1 0.1 1.0 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 FlxA PF14282.6 KKK40734.1 - 0.017 15.1 4.7 0.022 14.7 4.7 1.4 1 0 0 1 1 1 0 FlxA-like protein HIP1_clath_bdg PF16515.5 KKK40734.1 - 0.05 14.2 7.7 0.067 13.8 7.7 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Herpes_UL25 PF01499.16 KKK40734.1 - 0.078 11.5 2.3 0.078 11.5 2.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF2227 PF09988.9 KKK40735.1 - 0.029 14.2 0.6 0.068 13.0 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) PMSR PF01625.21 KKK40736.1 - 1.4e-36 126.0 0.2 1.6e-36 125.8 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase AlbA_2 PF04326.14 KKK40737.1 - 7.5e-11 42.4 0.1 3e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Putative DNA-binding domain DUF1689 PF07954.11 KKK40740.1 - 0.075 13.4 0.7 0.076 13.4 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) ERp29 PF07749.12 KKK40741.1 - 0.094 13.6 0.9 0.15 13.0 0.9 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF2540 PF10802.8 KKK40743.1 - 0.68 10.0 4.1 0.53 10.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Oxidored_FMN PF00724.20 KKK40744.1 - 2.4e-56 191.5 0.0 3.3e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 KKK40745.1 - 2.8e-56 191.2 0.0 3.5e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cation_efflux PF01545.21 KKK40746.1 - 1.1e-42 146.0 25.6 1.4e-42 145.7 25.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1230 PF06799.11 KKK40746.1 - 0.38 10.9 3.4 4.4 7.4 0.3 2.3 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 Sid-5 PF17204.3 KKK40746.1 - 2.2 8.5 4.2 1.1 9.5 0.6 2.3 2 0 0 2 2 2 0 Sid-5 family 12TM_1 PF09847.9 KKK40748.1 - 0.002 17.3 52.2 0.0035 16.5 52.2 1.4 1 0 0 1 1 1 1 Membrane protein of 12 TMs DUF2839 PF10999.8 KKK40748.1 - 0.15 12.4 0.4 1.5 9.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Phage_TAC_8 PF10666.9 KKK40753.1 - 0.02 15.2 0.4 0.041 14.2 0.4 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 CpxA_peri PF16527.5 KKK40753.1 - 0.064 13.6 0.1 0.14 12.5 0.0 1.6 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain N6_Mtase PF02384.16 KKK40754.1 - 8.6e-12 44.9 0.1 7e-07 28.8 0.0 3.0 3 0 0 3 3 3 2 N-6 DNA Methylase UPF0020 PF01170.18 KKK40754.1 - 8.4e-05 22.3 0.0 0.065 12.9 0.0 2.5 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 KKK40754.1 - 0.032 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KKK40754.1 - 0.077 12.5 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain YbaJ PF10757.9 KKK40754.1 - 3.2 8.3 8.7 6.3 7.4 0.5 3.4 3 0 0 3 3 3 0 Biofilm formation regulator YbaJ HTH_24 PF13412.6 KKK40757.1 - 0.00027 20.4 0.1 0.00067 19.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_45 PF14947.6 KKK40757.1 - 0.00037 20.4 2.5 0.19 11.7 0.4 2.6 2 1 0 2 2 2 2 Winged helix-turn-helix HTH_IclR PF09339.10 KKK40757.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_40 PF14493.6 KKK40757.1 - 0.16 12.4 2.7 0.33 11.5 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KKK40757.1 - 0.17 11.6 0.3 11 5.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, region 4 DUF4888 PF16229.5 KKK40758.1 - 0.0034 17.4 0.4 0.0063 16.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4888) Big_7 PF17957.1 KKK40759.1 - 3.5e-10 40.5 1.3 3.5e-10 40.5 1.3 2.3 2 0 0 2 2 2 1 Bacterial Ig domain Exo_endo_phos PF03372.23 KKK40759.1 - 1.6e-08 34.4 1.1 2.7e-08 33.6 1.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family VAPB_antitox PF02697.14 KKK40760.1 - 1.7e-12 47.9 8.1 2.7e-12 47.3 8.1 1.3 1 0 0 1 1 1 1 Putative antitoxin Lig_C PF18330.1 KKK40760.1 - 0.015 15.3 0.6 0.019 15.0 0.6 1.2 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region PIN PF01850.21 KKK40761.1 - 0.0077 16.7 0.0 0.0086 16.6 0.0 1.0 1 0 0 1 1 1 1 PIN domain PIN PF01850.21 KKK40762.1 - 0.0041 17.6 0.0 0.0041 17.6 0.0 1.0 1 0 0 1 1 1 1 PIN domain Acetyltransf_1 PF00583.25 KKK40763.1 - 7e-11 42.4 0.1 7.9e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK40763.1 - 2.2e-08 34.1 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK40763.1 - 1.4e-07 31.9 0.1 1.6e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK40763.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KKK40763.1 - 0.0064 16.2 0.0 0.0074 16.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 KKK40763.1 - 0.0065 16.4 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 KKK40763.1 - 0.008 16.3 0.0 0.0096 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK40763.1 - 0.032 14.4 0.0 0.05 13.7 0.0 1.4 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Neur_chan_memb PF02932.16 KKK40765.1 - 0.25 11.4 0.4 0.41 10.7 0.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TPR_12 PF13424.6 KKK40767.1 - 2.4e-60 200.7 12.9 2e-13 50.4 0.0 6.2 3 1 5 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 KKK40767.1 - 1.8e-35 119.8 9.9 6.1e-05 22.8 0.3 10.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 KKK40767.1 - 7.9e-34 113.0 9.8 0.00041 20.3 0.1 10.9 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 KKK40767.1 - 1.7e-31 106.7 25.1 6.5e-05 22.6 0.1 10.4 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 KKK40767.1 - 1.6e-21 74.6 27.8 0.00079 19.5 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK40767.1 - 1.9e-18 66.9 2.9 1.7e-07 30.9 0.0 3.9 1 1 2 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 KKK40767.1 - 3e-14 51.9 7.8 0.43 10.7 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat SNAP PF14938.6 KKK40767.1 - 5.7e-12 45.7 6.9 3.6e-06 26.6 1.2 3.2 2 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP SIR2_2 PF13289.6 KKK40767.1 - 9.1e-12 45.3 0.1 5.6e-11 42.7 0.0 2.4 2 0 0 2 2 1 1 SIR2-like domain TPR_11 PF13414.6 KKK40767.1 - 7.6e-10 38.3 14.8 0.0021 17.7 0.4 8.8 9 0 0 9 9 9 1 TPR repeat TPR_14 PF13428.6 KKK40767.1 - 3.5e-09 36.7 0.0 4.8 8.3 0.0 7.7 7 2 2 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK40767.1 - 1.6e-08 34.9 6.3 0.97 10.0 0.0 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK40767.1 - 2e-06 28.4 0.0 0.28 11.8 0.0 5.4 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK40767.1 - 0.00026 21.4 9.6 0.49 11.1 0.0 7.0 9 0 0 9 9 7 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KKK40767.1 - 0.00066 19.7 6.2 1.8 8.7 0.0 5.0 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 KKK40767.1 - 0.0013 18.8 2.8 0.21 11.7 0.3 4.4 1 1 3 5 5 5 1 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 KKK40767.1 - 0.0018 18.5 10.8 2.1 8.6 0.1 5.8 4 2 4 8 8 6 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF5113 PF17140.4 KKK40767.1 - 0.0019 18.0 15.2 1.3 8.8 0.0 5.4 5 1 1 6 6 6 3 Domain of unknown function (DUF5113) Vps39_1 PF10366.9 KKK40767.1 - 0.0027 18.0 5.6 4.3 7.7 0.4 4.5 2 1 2 4 4 4 1 Vacuolar sorting protein 39 domain 1 MIT PF04212.18 KKK40767.1 - 0.031 14.3 16.5 5.9 7.0 0.8 5.8 4 2 1 6 6 5 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.12 KKK40767.1 - 0.043 13.8 10.3 1.8 8.6 0.5 5.3 4 2 1 5 5 4 0 Protein of unknown function (DUF627) Rapsyn_N PF10579.9 KKK40767.1 - 0.047 13.8 6.4 46 4.2 0.1 5.0 4 1 1 5 5 5 0 Rapsyn N-terminal myristoylation and linker region DUF2972 PF11186.8 KKK40767.1 - 0.081 12.8 0.2 0.081 12.8 0.2 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2972) SPO22 PF08631.10 KKK40767.1 - 0.17 11.3 7.4 2.9 7.3 0.1 3.5 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF2989 PF11207.8 KKK40767.1 - 6.8 6.4 9.5 0.38 10.5 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2989) RPN6_N PF18055.1 KKK40767.1 - 8.4 6.8 11.9 1.7 9.0 0.9 4.0 4 0 0 4 4 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Hrs_helical PF12210.8 KKK40770.1 - 0.066 13.8 3.2 0.15 12.6 3.1 1.8 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF148 PF02520.17 KKK40770.1 - 0.25 11.5 11.4 5.5 7.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 Lectin_N PF03954.14 KKK40770.1 - 0.35 10.6 2.8 13 5.5 0.1 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Prominin PF05478.11 KKK40770.1 - 0.63 7.9 13.7 1.5 6.7 8.4 1.9 1 1 1 2 2 2 0 Prominin HSCB_C PF07743.13 KKK40770.1 - 2.3 8.8 7.7 6.6 7.3 1.7 3.3 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain GrpE PF01025.19 KKK40770.1 - 2.3 7.9 15.8 0.78 9.4 3.5 2.3 1 1 0 2 2 2 0 GrpE IZUMO PF15005.6 KKK40770.1 - 2.3 8.7 10.9 2.6 8.6 0.5 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated zinc_ribbon_2 PF13240.6 KKK40772.1 - 0.00012 21.7 1.3 0.00022 20.8 1.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK40772.1 - 0.0016 18.4 0.6 0.0022 18.0 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK40772.1 - 0.0044 17.7 0.6 0.0049 17.6 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK40772.1 - 0.0053 16.1 3.0 31 4.2 0.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_7 PF02591.15 KKK40772.1 - 0.024 14.8 3.3 0.17 12.1 0.1 2.2 1 1 1 2 2 2 0 C4-type zinc ribbon domain zf-LITAF-like PF10601.9 KKK40772.1 - 1.5 9.1 5.6 0.53 10.6 1.9 2.1 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Unstab_antitox PF09720.10 KKK40773.1 - 1.6e-10 40.9 0.3 2e-10 40.5 0.3 1.2 1 0 0 1 1 1 1 Putative addiction module component Borrelia_lipo_1 PF05714.11 KKK40773.1 - 0.0018 18.1 3.7 0.0019 18.0 3.7 1.0 1 0 0 1 1 1 1 Borrelia burgdorferi virulent strain associated lipoprotein zf-C4_Topoisom PF01396.19 KKK40775.1 - 1.4e-13 50.4 5.5 1.7e-13 50.1 5.5 1.2 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.6 KKK40775.1 - 0.00014 21.4 5.3 0.013 15.2 0.3 1.7 1 1 1 2 2 2 2 zinc-ribbon domain YhfH PF14149.6 KKK40775.1 - 0.00075 19.4 0.4 0.00097 19.1 0.4 1.3 1 0 0 1 1 1 1 YhfH-like protein zf-ribbon_3 PF13248.6 KKK40775.1 - 0.0067 15.8 0.4 0.011 15.2 0.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KKK40775.1 - 0.014 15.4 2.7 0.059 13.4 2.7 1.9 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DUF2256 PF10013.9 KKK40775.1 - 0.075 13.2 0.1 0.087 13.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) MG4 PF17789.1 KKK40776.1 - 0.0023 18.1 0.2 0.12 12.6 0.0 2.6 2 0 0 2 2 2 1 Macroglobulin domain MG4 Big_3_5 PF16640.5 KKK40776.1 - 0.025 14.7 0.2 0.14 12.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Ig_2 PF13895.6 KKK40776.1 - 0.11 12.8 0.2 0.58 10.5 0.1 2.4 2 0 0 2 2 2 0 Immunoglobulin domain CarboxypepD_reg PF13620.6 KKK40776.1 - 0.14 12.5 0.1 35 4.8 0.0 2.9 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DUF433 PF04255.14 KKK40779.1 - 9.1e-18 63.9 0.1 1.2e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF433) Peptidase_M50 PF02163.22 KKK40780.1 - 0.012 14.9 0.1 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M50 DUF2207 PF09972.9 KKK40780.1 - 0.21 10.3 4.5 0.18 10.5 0.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Polyketide_cyc2 PF10604.9 KKK40782.1 - 9.4e-06 26.0 0.0 1.2e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 KKK40782.1 - 4.1e-05 23.8 0.1 5e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 KKK40782.1 - 0.002 18.3 0.0 0.0027 17.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport VirE_N PF08800.10 KKK40782.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 VirE N-terminal domain Dynein_heavy PF03028.15 KKK40783.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain Acetyltransf_1 PF00583.25 KKK40784.1 - 1.9e-05 24.9 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK40784.1 - 0.0007 20.0 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK40784.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF2719 PF10891.8 KKK40784.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) Pribosyltran PF00156.27 KKK40785.1 - 0.00016 21.2 0.0 0.00018 21.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 KKK40785.1 - 0.058 12.9 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.6 KKK40785.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF3368 PF11848.8 KKK40786.1 - 0.0033 17.2 2.8 0.014 15.2 0.5 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3368) Unstab_antitox PF09720.10 KKK40787.1 - 1.6e-10 40.9 0.3 2e-10 40.5 0.3 1.2 1 0 0 1 1 1 1 Putative addiction module component Borrelia_lipo_1 PF05714.11 KKK40787.1 - 0.0018 18.1 3.7 0.0019 18.0 3.7 1.0 1 0 0 1 1 1 1 Borrelia burgdorferi virulent strain associated lipoprotein ParE_toxin PF05016.15 KKK40788.1 - 3.5e-09 37.2 0.1 4.1e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE DUF4984 PF16372.5 KKK40788.1 - 0.042 13.8 0.2 0.14 12.1 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4984) DUF2384 PF09722.10 KKK40789.1 - 0.067 13.2 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) CDC48_2 PF02933.17 KKK40790.1 - 7e-08 32.1 0.1 9.6e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 APH PF01636.23 KKK40792.1 - 7.1e-26 91.6 0.0 3.8e-25 89.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK40792.1 - 0.0026 17.4 0.0 0.0047 16.5 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KKK40792.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 KKK40792.1 - 0.061 12.9 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family UPF0175 PF03683.13 KKK40793.1 - 3e-08 33.3 0.1 3.5e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) PIN PF01850.21 KKK40794.1 - 0.0014 19.2 1.0 0.11 13.1 0.4 2.4 2 1 0 2 2 2 1 PIN domain DUF3368 PF11848.8 KKK40794.1 - 0.0053 16.5 0.4 0.015 15.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3368) PIN_5 PF08745.11 KKK40794.1 - 0.0084 15.6 0.1 0.093 12.1 0.0 2.0 1 1 1 2 2 2 1 PINc domain ribonuclease PIN_9 PF18477.1 KKK40794.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.6 1 1 0 1 1 1 0 PIN like domain TruB_N PF01509.18 KKK40797.1 - 6.3e-24 85.0 1.3 2.8e-19 70.0 1.3 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.12 KKK40797.1 - 1e-19 70.3 0.1 1.9e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 DKCLD (NUC011) domain Ribosomal_L2_C PF03947.18 KKK40798.1 - 1.7e-39 134.9 0.6 2.5e-39 134.4 0.6 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KKK40798.1 - 1.3e-12 47.5 0.0 8e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Asparaginase PF00710.20 KKK40799.1 - 1.1e-54 184.9 0.1 1.7e-54 184.3 0.1 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KKK40799.1 - 2.3e-31 108.3 0.0 5.8e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain GatD_N PF18195.1 KKK40799.1 - 2e-21 75.0 2.3 4.7e-21 73.9 2.3 1.7 1 0 0 1 1 1 1 GatD N-terminal domain zf-CCCH_8 PF18633.1 KKK40799.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 GatB_N PF02934.15 KKK40800.1 - 2.5e-59 200.9 0.1 3.8e-59 200.3 0.1 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KKK40800.1 - 1e-17 64.4 3.3 3e-17 62.9 3.3 1.8 1 0 0 1 1 1 1 GatB domain YqeY PF09424.10 KKK40800.1 - 4.3e-06 26.9 0.5 1.3e-05 25.3 0.5 1.8 1 0 0 1 1 1 1 Yqey-like protein GAD PF02938.14 KKK40800.1 - 6.1e-06 26.4 1.5 0.00012 22.3 0.2 2.5 2 0 0 2 2 2 1 GAD domain Nucleolin_bd PF16725.5 KKK40802.1 - 0.0019 17.8 0.3 0.49 10.1 0.0 2.6 2 0 0 2 2 2 2 Nucleolin binding domain HicB_lk_antitox PF15919.5 KKK40802.1 - 0.025 14.7 0.3 0.18 11.9 0.1 2.3 2 1 0 3 3 3 0 HicB_like antitoxin of bacterial toxin-antitoxin system Radical_SAM_C PF16199.5 KKK40803.1 - 1.4e-26 92.3 0.0 3e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KKK40803.1 - 1.6e-19 70.9 0.1 3.6e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KKK40803.1 - 0.00058 20.1 0.0 0.002 18.3 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_39 PF14090.6 KKK40803.1 - 0.0063 16.2 0.9 2.5 7.9 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain DUF5020 PF16412.5 KKK40803.1 - 0.017 15.0 0.1 0.081 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5020) DHODB_Fe-S_bind PF10418.9 KKK40804.1 - 7e-10 38.6 2.6 1.3e-09 37.7 2.6 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 KKK40804.1 - 0.00017 21.9 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKK40804.1 - 0.0096 16.0 0.6 0.042 14.0 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DHO_dh PF01180.21 KKK40805.1 - 6.5e-60 202.8 4.0 7.3e-60 202.7 4.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 KKK40805.1 - 1.7e-11 43.8 0.4 8.5e-07 28.4 0.1 2.9 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 KKK40805.1 - 1.3e-06 28.1 1.9 6.4e-06 25.8 1.9 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK40805.1 - 0.00011 21.3 0.7 0.00049 19.2 0.6 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KKK40805.1 - 0.0002 20.9 0.5 0.00069 19.1 0.1 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 KKK40805.1 - 0.0025 16.9 1.5 0.031 13.3 1.6 2.1 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DUF561 PF04481.12 KKK40805.1 - 0.0027 16.9 2.3 0.013 14.7 2.3 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF561) PcrB PF01884.17 KKK40805.1 - 0.005 16.3 0.3 1.3 8.4 0.0 2.6 3 0 0 3 3 3 2 PcrB family G3P_antiterm PF04309.12 KKK40805.1 - 0.021 14.3 0.4 0.51 9.7 0.0 3.2 4 0 0 4 4 4 0 Glycerol-3-phosphate responsive antiterminator PapG_C PF03628.13 KKK40805.1 - 0.082 12.8 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 PapG chaperone-binding domain ThiG PF05690.14 KKK40805.1 - 1.1 8.6 3.5 5.8 6.1 0.1 2.5 2 1 0 3 3 3 0 Thiazole biosynthesis protein ThiG Aminotran_1_2 PF00155.21 KKK40808.1 - 2.5e-42 145.3 0.0 3.2e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK40808.1 - 9.7e-09 34.6 0.0 1.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 KKK40808.1 - 4.8e-05 22.4 0.0 6.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 KKK40808.1 - 8.6e-05 21.2 0.0 0.00014 20.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK40808.1 - 0.27 10.5 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Fer4_5 PF12801.7 KKK40809.1 - 1e-13 51.0 22.9 3.3e-10 39.8 3.2 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4 PF00037.27 KKK40809.1 - 3.3e-05 23.5 22.2 0.0052 16.6 2.2 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 KKK40809.1 - 0.00097 19.3 23.1 0.0045 17.1 11.9 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK40809.1 - 0.0039 17.3 10.6 0.0039 17.3 10.6 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK40809.1 - 0.0072 16.9 17.5 0.051 14.2 12.4 3.2 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK40809.1 - 0.0077 16.3 2.0 0.0077 16.3 2.0 3.3 4 0 0 4 4 3 1 4Fe-4S binding domain Fer4_16 PF13484.6 KKK40809.1 - 1.1 10.2 20.0 0.97 10.4 1.9 3.8 3 1 2 5 5 5 0 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 KKK40809.1 - 1.5 9.4 18.6 2.1e+03 -0.6 18.6 3.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK40809.1 - 1.6 9.0 13.5 7.1 6.9 9.9 3.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK40809.1 - 5.4 7.5 17.9 9.6e+03 -2.9 17.9 2.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK40809.1 - 6.7 6.9 15.6 8.4 6.6 10.7 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain PWI PF01480.17 KKK40812.1 - 0.64 10.4 5.6 7.6 6.9 0.0 3.5 4 0 0 4 4 4 0 PWI domain SWIRM PF04433.17 KKK40812.1 - 0.76 10.2 9.8 0.083 13.2 2.2 3.2 3 1 0 3 3 3 0 SWIRM domain SBDS_C PF09377.10 KKK40813.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain HHH_2 PF12826.7 KKK40813.1 - 0.048 13.8 0.3 5.2 7.2 0.1 2.7 2 1 1 3 3 3 0 Helix-hairpin-helix motif TFIIE_alpha PF02002.17 KKK40813.1 - 0.12 12.2 0.6 0.18 11.7 0.1 1.5 2 0 0 2 2 2 0 TFIIE alpha subunit MFS_1 PF07690.16 KKK40814.1 - 0.0047 15.9 15.0 0.0047 15.9 15.0 3.2 1 1 0 2 2 2 1 Major Facilitator Superfamily TRAM1 PF08390.11 KKK40814.1 - 0.21 11.3 6.0 0.71 9.6 1.3 2.7 2 0 0 2 2 2 0 TRAM1-like protein Exo_endo_phos PF03372.23 KKK40815.1 - 2.2e-14 53.6 0.1 3.4e-14 52.9 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Flavodoxin_3 PF12641.7 KKK40816.1 - 0.0037 17.0 0.1 0.0037 17.0 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 KKK40817.1 - 5.2e-07 29.5 0.0 5.9e-07 29.3 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.7 KKK40817.1 - 3e-06 27.5 0.0 3.1e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 KKK40817.1 - 2.3e-05 24.6 0.0 2.7e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_4 PF12682.7 KKK40817.1 - 0.055 13.2 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin TatD_DNase PF01026.21 KKK40818.1 - 7.2e-40 137.0 0.0 8.4e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase PHINT_rpt PF14882.6 KKK40818.1 - 0.37 11.1 3.0 0.37 11.1 0.5 2.2 2 0 0 2 2 2 0 Phage-integrase repeat unit Phage_Mu_Gam PF07352.12 KKK40819.1 - 0.0045 16.9 3.7 0.0085 16.0 3.7 1.7 1 1 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF3086 PF11285.8 KKK40819.1 - 0.011 14.8 1.4 0.015 14.4 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) LemA PF04011.12 KKK40819.1 - 0.048 13.5 0.8 0.13 12.1 0.4 1.9 1 1 1 2 2 2 0 LemA family MLD PF11647.8 KKK40819.1 - 0.081 13.2 0.3 0.56 10.5 0.0 2.5 2 2 1 3 3 3 0 Membrane Localization Domain Baculo_PEP_C PF04513.12 KKK40819.1 - 0.16 12.0 0.1 0.77 9.8 0.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ax_dynein_light PF10211.9 KKK40819.1 - 0.19 11.7 9.1 0.1 12.6 5.2 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF1664 PF07889.12 KKK40819.1 - 0.31 11.1 2.9 1 9.4 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KKK40819.1 - 1.1 9.6 7.8 12 6.3 3.4 3.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TcpS PF17456.2 KKK40819.1 - 3.6 7.6 10.2 13 5.8 6.7 2.5 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S DUF4200 PF13863.6 KKK40821.1 - 0.022 15.2 30.0 0.036 14.5 15.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF1192 PF06698.11 KKK40821.1 - 0.031 14.3 3.6 0.031 14.3 3.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Phasin PF05597.11 KKK40821.1 - 0.67 10.0 16.0 4.8 7.2 16.0 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FAM76 PF16046.5 KKK40821.1 - 0.72 9.2 21.4 1.3 8.3 21.4 1.4 1 1 0 1 1 1 0 FAM76 protein SlyX PF04102.12 KKK40821.1 - 1.7 9.3 6.4 0.44 11.2 1.3 2.4 2 1 1 3 3 3 0 SlyX NPV_P10 PF05531.12 KKK40821.1 - 3.2 8.3 8.0 6.9 7.2 0.5 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KKK40821.1 - 4.7 6.5 22.9 8.4 5.6 22.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BST2 PF16716.5 KKK40821.1 - 5.8 7.6 18.2 1.2 9.7 12.9 2.3 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 MCU PF04678.13 KKK40821.1 - 6.3 6.9 18.2 0.47 10.5 10.8 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter PDE4_UCR PF18100.1 KKK40821.1 - 8.5 7.0 10.0 4.4 8.0 7.6 1.7 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) NosD PF05048.13 KKK40822.1 - 1.4e-86 289.7 174.3 3.4e-28 98.5 46.9 3.3 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK40822.1 - 1e-51 174.9 132.5 2.3e-24 86.1 37.7 5.0 2 1 3 5 5 5 4 Right handed beta helix region Phage_CI_C PF16452.5 KKK40822.1 - 1.3 9.4 4.4 15 5.9 0.1 3.3 3 0 0 3 3 3 0 Bacteriophage CI repressor C-terminal domain MORN_2 PF07661.13 KKK40822.1 - 8.1 7.0 7.1 16 6.1 0.1 4.0 4 0 0 4 4 4 0 MORN repeat variant Aconitase PF00330.20 KKK40823.1 - 1.5e-102 344.0 2.1 1.3e-100 337.6 2.1 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK40823.1 - 5.8e-21 75.2 0.1 1.6e-20 73.8 0.1 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KKK40823.1 - 0.0028 16.4 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) HARP PF07443.13 KKK40824.1 - 0.0061 16.2 0.3 0.034 13.8 0.0 2.6 3 0 0 3 3 3 1 HepA-related protein (HARP) Alkyl_sulf_dimr PF14863.6 KKK40824.1 - 0.021 15.3 2.3 4.5 7.7 0.2 2.4 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation SLATT_1 PF18181.1 KKK40824.1 - 0.46 10.4 2.5 0.6 10.0 0.4 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Retrotrans_gag PF03732.17 KKK40824.1 - 0.6 10.4 5.9 0.91 9.8 0.5 3.1 1 1 1 2 2 2 0 Retrotransposon gag protein Telomere_reg-2 PF10193.9 KKK40824.1 - 7 7.1 13.6 1.8 9.0 2.6 3.4 2 1 1 3 3 3 0 Telomere length regulation protein DUF4473 PF14747.6 KKK40825.1 - 2.3 8.8 13.2 0.12 13.0 1.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4473) TipAS PF07739.13 KKK40825.1 - 3 8.4 11.9 0.8 10.3 0.8 4.0 2 2 2 4 4 4 0 TipAS antibiotic-recognition domain DUF5320 PF17253.2 KKK40825.1 - 3.6 8.7 5.6 30 5.7 1.0 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Eco57I PF07669.11 KKK40825.1 - 4.3 7.9 7.4 2.5 8.6 0.1 3.6 3 1 1 4 4 4 0 Eco57I restriction-modification methylase DUF4386 PF14329.6 KKK40828.1 - 0.0046 16.9 1.7 0.0055 16.6 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) PalH PF08733.10 KKK40828.1 - 0.25 10.3 2.8 0.27 10.2 2.8 1.0 1 0 0 1 1 1 0 PalH/RIM21 HATPase_c PF02518.26 KKK40829.1 - 5e-24 85.0 0.8 1.3e-23 83.6 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK40829.1 - 3.6e-13 49.3 0.1 9.2e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ORMDL PF04061.14 KKK40829.1 - 0.012 15.5 4.6 0.27 11.1 0.9 2.4 1 1 1 2 2 2 0 ORMDL family HATPase_c_2 PF13581.6 KKK40829.1 - 0.015 15.2 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 KKK40829.1 - 0.049 13.5 1.7 0.19 11.6 0.6 2.4 2 1 0 2 2 2 0 GHKL domain HATPase_c_3 PF13589.6 KKK40829.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CSD PF00313.22 KKK40830.1 - 1.7e-27 95.0 0.9 2.1e-27 94.7 0.9 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KKK40830.1 - 5.7e-07 29.1 1.1 4.3e-06 26.3 1.1 2.1 1 1 0 1 1 1 1 Ribonuclease B OB domain Ras PF00071.22 KKK40831.1 - 1.5e-41 141.7 0.2 1.6e-41 141.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40831.1 - 3.4e-27 95.0 0.1 4.6e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40831.1 - 5.4e-12 45.5 0.0 6.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK40831.1 - 2.3e-06 27.1 0.1 2.8e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK40831.1 - 4.1e-06 26.9 0.0 7.3e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK40831.1 - 0.00061 19.7 0.2 0.82 9.5 0.0 2.6 1 1 2 3 3 3 2 RsgA GTPase AAA_24 PF13479.6 KKK40831.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Tae4 PF14113.6 KKK40831.1 - 0.015 15.5 0.1 0.026 14.7 0.1 1.4 1 1 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 cobW PF02492.19 KKK40831.1 - 0.02 14.5 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KKK40831.1 - 0.026 15.1 0.1 0.051 14.1 0.0 1.6 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KKK40831.1 - 0.052 13.3 0.1 8.6 6.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KKK40831.1 - 0.065 12.8 0.1 8.6 5.8 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain URO-D PF01208.17 KKK40835.1 - 0.055 12.6 0.0 0.71 9.0 0.0 2.0 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Y1_Tnp PF01797.16 KKK40835.1 - 0.09 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase IS200 like DUF760 PF05542.11 KKK40836.1 - 0.0038 17.5 0.2 0.0047 17.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF760) ADH_N_assoc PF13823.6 KKK40836.1 - 0.21 11.6 0.4 0.36 10.8 0.4 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Amidohydro_2 PF04909.14 KKK40838.1 - 3.9e-29 102.4 0.0 4.5e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Cyclase PF04199.13 KKK40839.1 - 2.3e-31 108.9 0.2 2.9e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 Putative cyclase Hist_deacetyl PF00850.19 KKK40841.1 - 1.2e-62 212.2 0.0 1.8e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Profilin PF00235.19 KKK40842.1 - 0.00011 22.4 0.0 0.00013 22.3 0.0 1.1 1 0 0 1 1 1 1 Profilin dCache_1 PF02743.18 KKK40842.1 - 0.0037 17.1 0.1 0.017 14.9 0.1 1.6 1 1 0 1 1 1 1 Cache domain FtsX PF02687.21 KKK40843.1 - 2.3e-05 24.7 8.9 2.3e-05 24.7 8.9 2.8 1 1 1 2 2 2 1 FtsX-like permease family OSTMP1 PF09777.9 KKK40843.1 - 4.8 6.5 5.7 0.37 10.1 0.5 1.7 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor ABC_tran PF00005.27 KKK40844.1 - 2.5e-31 109.0 0.0 3.5e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK40844.1 - 4.1e-05 23.1 0.2 0.00051 19.5 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK40844.1 - 4.4e-05 23.4 0.2 0.022 14.6 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KKK40844.1 - 0.00012 22.4 1.5 0.0049 17.1 1.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK40844.1 - 0.00019 21.9 0.0 0.0003 21.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KKK40844.1 - 0.00036 19.7 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KKK40844.1 - 0.00071 19.5 0.1 0.0018 18.2 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 KKK40844.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 KKK40844.1 - 0.0028 17.4 0.1 0.0051 16.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KKK40844.1 - 0.0072 15.9 0.1 0.016 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KKK40844.1 - 0.0083 16.3 0.3 0.12 12.6 0.3 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KKK40844.1 - 0.0086 16.6 0.8 0.02 15.4 0.0 1.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK40844.1 - 0.023 14.4 0.0 0.54 10.0 0.0 2.6 2 1 1 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KKK40844.1 - 0.03 14.7 0.0 0.097 13.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 KKK40844.1 - 0.033 13.0 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 KKK40844.1 - 0.033 14.3 0.1 0.06 13.4 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KKK40844.1 - 0.064 13.5 0.1 0.17 12.1 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 KKK40844.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK40844.1 - 0.089 13.3 0.4 0.2 12.2 0.1 1.8 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KKK40844.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family DUF362 PF04015.12 KKK40845.1 - 1.9e-38 132.8 0.4 2.4e-38 132.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF362) zf-ribbon_3 PF13248.6 KKK40846.1 - 2.3e-07 30.0 1.6 4e-07 29.2 1.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK40846.1 - 1.3e-05 24.7 2.3 2.1e-05 24.0 2.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK40846.1 - 0.00013 22.0 0.3 0.0002 21.3 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK40846.1 - 0.00077 20.2 0.5 0.0012 19.5 0.5 1.3 1 0 0 1 1 1 1 zinc-ribbon family zf-HYPF PF07503.12 KKK40846.1 - 0.23 11.3 2.0 2.7 7.9 0.1 2.3 2 0 0 2 2 2 0 HypF finger TF_Zn_Ribbon PF08271.12 KKK40846.1 - 0.6 9.7 3.7 1.2 8.7 3.7 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Phage_holin_3_7 PF05449.11 KKK40847.1 - 0.0049 16.9 5.5 0.68 10.0 0.3 2.8 2 0 0 2 2 2 2 Putative 3TM holin, Phage_holin_3 AMP-binding PF00501.28 KKK40849.1 - 1.2e-74 251.5 0.0 1.4e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK40849.1 - 2.2e-14 54.1 0.0 6.1e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ScsC_N PF18312.1 KKK40849.1 - 0.0086 15.9 0.4 0.017 14.9 0.4 1.5 1 0 0 1 1 1 1 Copper resistance protein ScsC N-terminal domain Penicillinase_R PF03965.16 KKK40850.1 - 0.0019 18.5 0.2 0.0063 16.8 0.1 1.9 2 0 0 2 2 2 1 Penicillinase repressor Plasmid_stab_B PF10784.9 KKK40850.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Plasmid stability protein Ras PF00071.22 KKK40851.1 - 7.3e-47 159.0 0.1 8.3e-47 158.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK40851.1 - 1.9e-27 95.9 0.1 2.4e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK40851.1 - 1.1e-15 57.5 0.0 1.3e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK40851.1 - 2.4e-08 33.6 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK40851.1 - 7.2e-06 25.5 0.0 8.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATPase_2 PF01637.18 KKK40851.1 - 0.00042 20.3 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KKK40851.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 KKK40851.1 - 0.0014 18.4 0.3 0.0069 16.1 0.1 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 KKK40851.1 - 0.0014 18.0 0.2 0.0026 17.1 0.1 1.4 2 0 0 2 2 2 1 KaiC MMR_HSR1 PF01926.23 KKK40851.1 - 0.0015 18.6 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK40851.1 - 0.0021 17.6 0.1 1.1 8.7 0.1 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KKK40851.1 - 0.0023 18.2 0.1 0.0068 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KKK40851.1 - 0.0039 16.9 0.5 0.0065 16.2 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK40851.1 - 0.0048 17.3 0.0 0.0048 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KKK40851.1 - 0.0066 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KKK40851.1 - 0.0078 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KKK40851.1 - 0.01 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KKK40851.1 - 0.012 15.6 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KKK40851.1 - 0.017 15.1 0.1 0.038 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KKK40851.1 - 0.023 14.7 0.3 0.054 13.5 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 KKK40851.1 - 0.024 13.9 0.2 0.064 12.5 0.1 1.7 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 KKK40851.1 - 0.024 15.1 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 KKK40851.1 - 0.03 14.1 0.0 2 8.1 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KKK40851.1 - 0.03 14.2 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KKK40851.1 - 0.047 12.9 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KKK40851.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 KKK40851.1 - 0.073 12.7 0.0 0.098 12.3 0.0 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 KKK40851.1 - 0.076 13.2 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MatB PF16449.5 KKK40851.1 - 0.081 12.7 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Fimbrillin MatB PRK PF00485.18 KKK40851.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 KKK40851.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_31 PF13847.6 KKK40851.1 - 0.096 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MobB PF03205.14 KKK40851.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.6 KKK40851.1 - 0.14 12.7 0.7 0.22 12.0 0.4 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK40851.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KKK40851.1 - 0.17 12.1 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KKK40851.1 - 0.19 10.8 0.4 4.5 6.3 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Fer4_9 PF13187.6 KKK40852.1 - 0.00012 22.2 9.2 0.00026 21.1 9.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK40852.1 - 0.00012 21.7 15.9 0.00037 20.2 3.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK40852.1 - 0.00035 21.4 13.5 0.0037 18.2 13.5 2.2 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK40852.1 - 0.00048 20.6 10.0 0.001 19.6 10.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK40852.1 - 0.0017 18.4 12.5 0.13 12.4 12.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK40852.1 - 0.0021 18.5 1.9 0.25 11.8 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40852.1 - 0.0027 17.7 10.7 0.022 14.8 2.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK40852.1 - 0.0031 17.5 10.9 0.026 14.6 3.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK40852.1 - 0.0059 16.7 13.8 0.19 11.9 14.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK40852.1 - 0.099 13.6 12.9 2.1 9.5 4.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK40852.1 - 1.3 9.6 10.1 35 5.0 10.3 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK40852.1 - 2 9.1 10.0 5.4 7.8 2.4 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Lin0512_fam PF09585.10 KKK40853.1 - 6.7e-38 129.2 0.2 7.7e-38 129.0 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) Dehalogenase PF13486.6 KKK40854.1 - 1.3e-23 83.9 0.0 8.5e-23 81.1 0.0 2.0 1 1 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 KKK40854.1 - 3.7e-09 37.4 9.5 1.1e-08 35.9 9.5 1.9 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK40854.1 - 2.4e-08 34.4 7.1 4.8e-08 33.5 7.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK40854.1 - 2.7e-05 23.8 11.7 0.0043 16.8 1.7 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK40854.1 - 3.2e-05 23.8 8.3 0.042 14.0 0.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK40854.1 - 0.00017 21.5 8.4 0.083 13.0 1.6 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK40854.1 - 0.0016 18.5 10.8 0.0044 17.1 10.9 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK40854.1 - 0.0028 18.0 11.7 0.018 15.5 1.2 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KKK40854.1 - 0.0029 17.7 10.9 0.027 14.6 11.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK40854.1 - 0.39 11.2 9.6 5.8 7.4 10.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK40854.1 - 0.62 10.6 10.8 3.4 8.3 11.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK40854.1 - 2.1 8.5 11.5 57 4.0 11.5 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK40854.1 - 2.8 9.1 10.6 4.4 8.5 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain tRNA-synt_1d PF00750.19 KKK40856.1 - 7.9e-44 150.0 1.3 1.2e-43 149.5 1.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KKK40856.1 - 7.6e-32 110.0 0.3 3.1e-31 108.0 0.2 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KKK40856.1 - 1.8e-11 44.5 0.2 5e-11 43.0 0.1 1.9 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain NTP_transf_5 PF14907.6 KKK40856.1 - 0.11 12.2 0.0 5.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase tRNA-synt_1g PF09334.11 KKK40856.1 - 0.35 9.6 3.1 0.4 9.4 0.0 2.6 4 0 0 4 4 4 0 tRNA synthetases class I (M) Arginase PF00491.21 KKK40857.1 - 2.7e-65 220.7 0.0 3.2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family DS PF01916.17 KKK40858.1 - 3.2e-87 292.5 0.0 3.8e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase SepSecS PF05889.13 KKK40858.1 - 0.17 10.6 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF148 PF02520.17 KKK40859.1 - 0.067 13.3 0.2 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 ProRS-C_2 PF09181.10 KKK40860.1 - 0.016 15.3 0.2 0.017 15.2 0.2 1.0 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal POR_N PF01855.19 KKK40865.1 - 1.5e-08 34.6 0.1 2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fer4 PF00037.27 KKK40866.1 - 2.7e-11 42.8 14.0 1.5e-06 27.7 2.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK40866.1 - 7.2e-10 38.9 14.5 9.8e-07 28.9 9.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK40866.1 - 8.9e-10 39.0 19.4 1.2e-07 32.2 8.7 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK40866.1 - 4.9e-08 33.8 12.4 0.00037 21.4 2.6 2.7 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 KKK40866.1 - 1.7e-07 31.0 10.8 0.0005 20.0 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK40866.1 - 2.8e-07 30.5 21.6 5.2e-05 23.3 11.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK40866.1 - 4.5e-07 30.2 2.0 0.018 15.4 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK40866.1 - 1.7e-06 28.1 9.1 3.8e-06 26.9 9.3 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK40866.1 - 9.7e-06 25.4 9.7 0.0017 18.3 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK40866.1 - 2e-05 25.0 5.2 0.074 13.6 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK40866.1 - 0.0048 17.3 12.3 0.078 13.5 1.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 KKK40866.1 - 0.015 16.0 8.2 0.031 15.0 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 KKK40866.1 - 0.082 13.5 11.7 0.3 11.6 1.6 2.3 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KKK40866.1 - 0.54 11.3 15.1 2.7 9.2 3.0 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK40866.1 - 0.84 10.5 12.5 0.85 10.5 2.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK40866.1 - 1 9.6 9.2 4.4 7.5 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain POR PF01558.18 KKK40867.1 - 4.4e-23 82.3 0.0 5.1e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase zf-ZPR1 PF03367.13 KKK40868.1 - 2.2e-32 112.1 0.0 2.6e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 ZPR1 zinc-finger domain RNA_POL_M_15KD PF02150.16 KKK40868.1 - 0.0045 16.8 1.3 0.037 13.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Surfac_D-trimer PF09006.11 KKK40868.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation PFK PF00365.20 KKK40869.1 - 4.5e-87 292.0 0.0 6.3e-87 291.5 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase baeRF_family12 PF18856.1 KKK40869.1 - 0.028 15.0 0.0 0.082 13.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 baeRF_family10 PF18854.1 KKK40869.1 - 0.054 13.7 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 NAD_kinase PF01513.21 KKK40869.1 - 0.063 12.5 0.1 0.15 11.2 0.1 1.6 1 1 1 2 2 2 0 ATP-NAD kinase DAGK_cat PF00781.24 KKK40869.1 - 0.087 12.4 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Radical_SAM PF04055.21 KKK40870.1 - 3.5e-19 69.8 0.8 1.1e-18 68.1 0.4 2.1 3 0 0 3 3 3 1 Radical SAM superfamily B12-binding PF02310.19 KKK40870.1 - 3.7e-18 65.7 0.1 1.4e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 B12 binding domain Acyl-CoA_dh_1 PF00441.24 KKK40871.1 - 2e-34 119.0 0.2 2.9e-34 118.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK40871.1 - 2e-26 92.9 0.0 6.7e-26 91.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKK40871.1 - 8.6e-18 64.9 0.0 1.3e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK40871.1 - 1.2e-15 57.5 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MFS_1 PF07690.16 KKK40872.1 - 9.6e-66 222.1 72.4 1.1e-48 166.0 36.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KKK40872.1 - 8.4e-10 37.6 15.2 2.6e-09 36.1 15.2 1.7 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 KKK40872.1 - 1.4e-09 37.1 44.0 3.2e-06 26.0 19.4 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KKK40872.1 - 1.3e-08 34.1 35.7 0.00029 19.8 16.1 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KKK40872.1 - 5.4e-05 22.2 11.5 5.4e-05 22.2 11.5 3.0 1 1 1 2 2 2 1 Sugar (and other) transporter GatB_Yqey PF02637.18 KKK40873.1 - 0.0058 16.5 1.2 0.79 9.6 0.2 2.7 2 1 0 2 2 2 2 GatB domain Pro-kuma_activ PF09286.11 KKK40873.1 - 0.0087 16.4 0.3 0.044 14.1 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain EcoEI_R_C PF08463.10 KKK40873.1 - 0.017 15.2 0.3 0.017 15.2 0.3 1.9 1 1 0 2 2 2 0 EcoEI R protein C-terminal Imm53 PF15580.6 KKK40873.1 - 0.035 13.8 1.0 0.098 12.4 1.0 1.7 1 0 0 1 1 1 0 Immunity protein 53 Ground-like PF04155.18 KKK40873.1 - 0.037 14.7 0.0 0.12 13.1 0.0 1.9 1 0 0 1 1 1 0 Ground-like domain MyTH4 PF00784.17 KKK40873.1 - 0.082 13.4 0.3 4.9 7.7 0.0 2.6 1 1 1 2 2 2 0 MyTH4 domain zf-RING_7 PF02591.15 KKK40875.1 - 0.0034 17.5 0.8 1.5 9.1 0.1 2.5 2 0 0 2 2 2 2 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 KKK40875.1 - 0.0098 15.3 3.4 1.4 8.4 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-C2HC5 PF06221.13 KKK40875.1 - 0.093 12.7 0.3 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_2 PF13240.6 KKK40875.1 - 0.26 11.1 5.1 4.7 7.0 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.11 KKK40875.1 - 0.29 10.7 4.6 2.6 7.7 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-Di19 PF05605.12 KKK40875.1 - 0.72 10.2 1.9 3.9 7.9 0.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.7 KKK40875.1 - 3.5 7.7 6.6 66 3.6 6.5 2.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain FGGY_N PF00370.21 KKK40876.1 - 4.3e-71 239.4 0.0 7.1e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KKK40876.1 - 2.8e-40 138.2 0.0 3.9e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KKK40876.1 - 0.029 13.9 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Saf_2TM PF18303.1 KKK40877.1 - 0.097 12.3 0.3 0.097 12.3 0.3 2.9 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain Podoplanin PF05808.11 KKK40877.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 Podoplanin MtrB PF05440.12 KKK40877.1 - 0.45 11.0 0.0 0.45 11.0 0.0 2.6 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF87 PF01935.17 KKK40878.1 - 4.6e-29 102.1 3.8 2.7e-27 96.4 3.3 2.1 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_10 PF12846.7 KKK40878.1 - 0.033 13.1 0.0 5.9 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.29 KKK40880.1 - 1e-96 320.4 0.0 8.4e-48 162.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK40880.1 - 1.1e-27 95.6 3.1 2.3e-14 52.9 0.8 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KKK40880.1 - 4.7e-24 84.4 1.4 2.4e-23 82.1 1.4 2.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KKK40880.1 - 3.4e-16 59.8 0.0 1.2e-08 35.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KKK40880.1 - 8.3e-15 55.6 0.7 5.8e-06 26.8 0.0 4.1 3 2 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 KKK40880.1 - 2.4e-14 53.4 0.0 7.5e-07 29.0 0.0 3.1 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KKK40880.1 - 1.7e-11 44.2 0.0 2.3e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KKK40880.1 - 6e-10 39.3 0.5 0.0037 17.2 0.0 4.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK40880.1 - 9.8e-10 38.8 0.2 0.015 15.5 0.0 3.9 2 2 1 4 4 4 2 AAA domain TIP49 PF06068.13 KKK40880.1 - 1.5e-09 37.5 1.7 0.0026 17.0 0.0 3.4 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 KKK40880.1 - 4.5e-09 36.6 0.0 0.0025 18.0 0.0 3.1 4 0 0 4 4 2 2 AAA domain CDC48_2 PF02933.17 KKK40880.1 - 3.3e-07 30.0 0.0 1.1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.12 KKK40880.1 - 4.6e-07 29.3 0.0 0.026 13.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.22 KKK40880.1 - 5e-07 30.1 0.0 0.059 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 KKK40880.1 - 1.1e-06 28.2 0.4 0.038 13.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKK40880.1 - 1.6e-06 27.9 0.0 0.054 13.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 KKK40880.1 - 2.2e-06 27.7 0.0 0.23 11.4 0.0 3.4 3 1 1 4 4 3 2 NACHT domain ABC_tran PF00005.27 KKK40880.1 - 2.4e-06 28.1 0.0 0.11 12.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter Sigma54_activat PF00158.26 KKK40880.1 - 5.1e-06 26.3 0.0 0.065 12.9 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 KKK40880.1 - 6.8e-06 26.7 0.0 0.12 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KKK40880.1 - 1.1e-05 25.5 0.1 0.23 11.3 0.0 3.4 2 2 1 3 3 3 2 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KKK40880.1 - 1.1e-05 25.3 0.0 0.044 13.5 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KKK40880.1 - 2.6e-05 24.5 0.0 0.41 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain UFD1 PF03152.14 KKK40880.1 - 4.4e-05 23.0 0.6 0.00017 21.1 0.3 1.9 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 TsaE PF02367.17 KKK40880.1 - 5.5e-05 23.2 0.0 0.52 10.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KKK40880.1 - 6.7e-05 22.5 0.0 0.36 10.3 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 KKK40880.1 - 7.5e-05 22.7 0.1 0.9 9.4 0.0 3.1 2 1 1 3 3 3 2 Rad17 P-loop domain NTPase_1 PF03266.15 KKK40880.1 - 7.9e-05 22.6 3.2 7.7 6.4 0.1 5.0 4 2 2 6 6 5 0 NTPase AAA_25 PF13481.6 KKK40880.1 - 8.6e-05 22.2 0.1 0.62 9.6 0.0 3.8 4 0 0 4 4 3 1 AAA domain ATPase PF06745.13 KKK40880.1 - 9.3e-05 21.9 0.5 1.3 8.3 0.0 3.8 3 1 0 4 4 4 2 KaiC AAA_24 PF13479.6 KKK40880.1 - 9.7e-05 22.2 0.0 0.41 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KKK40880.1 - 0.00014 21.7 0.0 0.38 10.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKK40880.1 - 0.00021 20.6 0.0 0.57 9.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Bac_DnaA PF00308.18 KKK40880.1 - 0.00021 21.2 0.0 0.076 12.8 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein Vps4_C PF09336.10 KKK40880.1 - 0.00041 20.3 5.2 1.2 9.2 0.0 4.8 7 0 0 7 7 4 2 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 KKK40880.1 - 0.00042 20.7 0.0 2.1 8.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KKK40880.1 - 0.0016 17.9 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.13 KKK40880.1 - 0.0018 17.5 0.0 1.1 8.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.9 KKK40880.1 - 0.0035 16.6 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 KKK40880.1 - 0.0051 16.0 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.25 KKK40880.1 - 0.0054 16.4 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.22 KKK40880.1 - 0.0096 16.1 0.1 8.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Shikimate kinase Cytidylate_kin2 PF13189.6 KKK40880.1 - 0.011 15.8 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 KKK40880.1 - 0.013 15.6 0.0 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KKK40880.1 - 0.016 15.0 0.3 8.7 6.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KKK40880.1 - 0.023 14.5 0.0 9.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KKK40880.1 - 0.036 14.4 0.5 15 5.9 0.0 3.0 2 1 1 3 3 2 0 AAA domain SRPRB PF09439.10 KKK40880.1 - 0.051 13.0 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AFG1_ATPase PF03969.16 KKK40880.1 - 0.062 12.2 0.0 12 4.7 0.0 2.6 3 0 0 3 3 2 0 AFG1-like ATPase AAA_30 PF13604.6 KKK40880.1 - 0.083 12.6 0.0 8.6 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 KKK40880.1 - 0.12 12.2 0.0 21 4.9 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DAP3 PF10236.9 KKK40880.1 - 0.21 10.7 0.0 10 5.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 XPG_I PF00867.18 KKK40881.1 - 1.8e-25 89.1 0.0 5.1e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KKK40881.1 - 2.8e-20 72.7 0.1 8.1e-20 71.2 0.1 1.8 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KKK40881.1 - 3.2e-08 34.1 0.1 3.2e-08 34.1 0.1 2.6 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KKK40881.1 - 0.0036 17.4 0.0 0.0087 16.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KKK40881.1 - 0.01 16.4 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Tantalus PF15386.6 KKK40881.1 - 0.22 11.6 4.9 1.4 9.0 0.1 3.3 3 0 0 3 3 3 0 Drosophila Tantalus-like PIN_6 PF17146.4 KKK40882.1 - 6.2e-15 55.5 0.1 9.4e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 PIN domain of ribonuclease ADK_lid PF05191.14 KKK40882.1 - 0.0015 18.5 3.2 0.003 17.5 2.0 2.0 2 0 0 2 2 2 1 Adenylate kinase, active site lid DUF1272 PF06906.11 KKK40882.1 - 0.0026 17.8 0.8 0.0057 16.7 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) TF_Zn_Ribbon PF08271.12 KKK40882.1 - 0.0052 16.3 1.3 0.011 15.2 0.5 2.0 2 0 0 2 2 2 1 TFIIB zinc-binding Myb_DNA-bind_7 PF15963.5 KKK40882.1 - 0.024 14.5 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Myb DNA-binding like tRNA-synt_1g PF09334.11 KKK40882.1 - 0.037 12.8 0.2 0.037 12.8 0.2 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (M) DZR PF12773.7 KKK40882.1 - 0.039 14.0 0.9 0.072 13.1 0.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KKK40882.1 - 0.062 13.3 1.6 0.15 12.1 1.6 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KKK40882.1 - 0.19 11.8 1.8 0.45 10.7 1.8 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_3 PF13878.6 KKK40882.1 - 0.88 9.4 2.9 0.79 9.6 0.6 2.0 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO NAD_kinase PF01513.21 KKK40883.1 - 2.5e-43 148.4 2.1 2.4e-42 145.1 2.1 1.9 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KKK40883.1 - 0.00068 19.3 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF2701 PF10857.8 KKK40883.1 - 0.024 14.6 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) EFP_N PF08207.12 KKK40884.1 - 0.00053 20.0 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain STI1 PF17830.1 KKK40884.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 STI1 domain SRP54 PF00448.22 KKK40885.1 - 9.9e-70 234.2 1.7 1.8e-69 233.4 1.7 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KKK40885.1 - 2e-26 92.5 1.0 6.9e-26 90.8 1.0 2.0 1 0 0 1 1 1 1 Signal peptide binding domain SRP54_N PF02881.19 KKK40885.1 - 9.4e-13 48.2 3.8 9.4e-13 48.2 3.8 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KKK40885.1 - 9.5e-06 25.3 0.8 2.8e-05 23.8 0.6 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KKK40885.1 - 5e-05 23.5 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KKK40885.1 - 8.6e-05 21.9 0.1 0.00017 21.0 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KKK40885.1 - 9.9e-05 21.4 2.4 0.00053 19.1 0.1 2.7 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KKK40885.1 - 9.9e-05 22.1 0.1 0.00023 21.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 KKK40885.1 - 0.00011 21.5 0.1 0.00042 19.6 0.2 1.7 1 1 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 KKK40885.1 - 0.00024 21.6 0.2 0.0019 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.14 KKK40885.1 - 0.00035 20.5 0.6 0.00094 19.1 0.6 1.9 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 KKK40885.1 - 0.00037 20.6 0.0 0.0016 18.5 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KKK40885.1 - 0.0022 17.9 3.2 0.017 15.0 3.2 2.2 1 1 0 1 1 1 1 NTPase AAA_22 PF13401.6 KKK40885.1 - 0.0029 17.9 0.7 0.015 15.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KKK40885.1 - 0.005 17.3 2.4 0.013 16.0 0.3 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKK40885.1 - 0.0052 16.9 4.7 0.0057 16.7 1.3 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KKK40885.1 - 0.0064 16.3 0.5 0.013 15.3 0.5 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KKK40885.1 - 0.0075 15.7 0.4 0.59 9.6 0.1 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 KKK40885.1 - 0.0078 16.8 0.3 0.035 14.7 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KKK40885.1 - 0.0092 16.3 0.4 0.026 14.9 0.1 1.8 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.20 KKK40885.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase 6PF2K PF01591.18 KKK40885.1 - 0.014 14.7 0.1 0.039 13.3 0.1 1.7 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.6 KKK40885.1 - 0.024 14.7 0.7 0.092 12.8 0.7 2.1 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KKK40885.1 - 0.028 14.1 0.4 0.028 14.1 0.4 2.1 2 0 0 2 2 2 0 Thymidylate kinase ATPase PF06745.13 KKK40885.1 - 0.032 13.6 0.4 0.032 13.6 0.4 2.1 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 KKK40885.1 - 0.033 14.4 0.3 0.087 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.6 KKK40885.1 - 0.033 13.9 0.2 0.033 13.9 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KKK40885.1 - 0.035 13.8 0.5 0.4 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KKK40885.1 - 0.042 13.3 0.3 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_7 PF12775.7 KKK40885.1 - 0.043 13.3 1.4 0.064 12.8 0.1 1.9 2 0 0 2 2 1 0 P-loop containing dynein motor region MipZ PF09140.11 KKK40885.1 - 0.053 12.8 0.6 3.8 6.7 0.6 2.5 1 1 0 1 1 1 0 ATPase MipZ AAA PF00004.29 KKK40885.1 - 0.1 13.0 2.1 0.25 11.8 0.6 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PHP PF02811.19 KKK40885.1 - 0.12 12.6 0.1 0.73 10.1 0.1 2.3 1 1 0 1 1 1 0 PHP domain Fe-ADH_2 PF13685.6 KKK40885.1 - 0.13 11.9 1.3 18 4.9 0.0 3.1 3 1 0 3 3 3 0 Iron-containing alcohol dehydrogenase KAP_NTPase PF07693.14 KKK40885.1 - 0.13 11.4 2.1 0.2 10.8 0.6 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_5 PF07728.14 KKK40885.1 - 0.16 12.0 0.6 0.46 10.5 0.1 2.1 3 0 0 3 3 1 0 AAA domain (dynein-related subfamily) AAA_31 PF13614.6 KKK40885.1 - 0.2 11.6 5.7 0.096 12.6 0.3 2.5 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KKK40885.1 - 0.36 10.6 3.3 6.1 6.6 0.7 2.7 2 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KKK40885.1 - 0.66 10.5 3.8 1.2 9.7 2.1 2.2 2 1 0 2 2 2 0 ABC transporter ResIII PF04851.15 KKK40885.1 - 1.4 8.9 11.3 1.2 9.1 7.5 2.7 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KKK40885.1 - 1.6 8.6 7.4 0.55 10.1 1.4 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A3L PF05288.11 KKK40885.1 - 2.4 8.2 5.4 16 5.6 1.1 3.1 2 0 0 2 2 2 0 Poxvirus A3L Protein Methyltrn_RNA_2 PF04013.12 KKK40886.1 - 1.2e-07 31.6 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent RNA methyltransferase Amidohydro_1 PF01979.20 KKK40887.1 - 2.1e-16 60.2 0.0 1.5e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK40887.1 - 2.2e-06 27.4 0.0 0.043 13.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family AMMECR1 PF01871.17 KKK40888.1 - 4.6e-44 150.0 0.0 5.2e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 IMS PF00817.20 KKK40890.1 - 1e-42 145.7 0.0 2.3e-42 144.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KKK40890.1 - 7e-15 55.8 0.4 1.6e-14 54.6 0.4 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KKK40890.1 - 0.00022 21.3 0.0 0.00086 19.5 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif Thioredoxin_8 PF13905.6 KKK40890.1 - 0.027 14.8 1.7 6 7.3 0.2 3.0 2 1 0 2 2 2 0 Thioredoxin-like MetOD2 PF18548.1 KKK40890.1 - 0.089 12.9 1.4 23 5.2 0.0 3.2 3 0 0 3 3 3 0 Metanogen output domain 2 Aldolase_II PF00596.21 KKK40891.1 - 2.2e-40 138.6 0.1 2.6e-40 138.3 0.1 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RHH_1 PF01402.21 KKK40893.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family NikR_C PF08753.11 KKK40893.1 - 0.0023 18.1 0.1 0.0044 17.1 0.1 1.4 1 0 0 1 1 1 1 NikR C terminal nickel binding domain baeRF_family5 PF18846.1 KKK40893.1 - 0.01 16.0 0.1 0.018 15.2 0.1 1.4 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 QRPTase_C PF01729.19 KKK40894.1 - 2.8e-44 150.9 0.4 4.6e-44 150.2 0.4 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KKK40894.1 - 6.4e-21 74.2 0.0 1.5e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF1959 PF09218.10 KKK40894.1 - 0.07 13.3 0.9 9.5 6.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1959) KDGP_aldolase PF07071.11 KKK40894.1 - 0.076 12.8 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 KDGP aldolase Hydrolase_4 PF12146.8 KKK40895.1 - 3.6e-05 23.2 0.0 0.00088 18.6 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK40895.1 - 0.00028 20.6 0.2 0.011 15.3 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK40895.1 - 0.0095 16.6 0.0 0.0098 16.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KKK40895.1 - 0.05 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KKK40895.1 - 0.12 11.9 0.0 0.56 9.6 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family ADH_zinc_N_2 PF13602.6 KKK40896.1 - 3.5e-05 24.9 0.0 3.7e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK40897.1 - 0.027 14.4 0.1 0.027 14.4 0.1 1.0 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain HMGL-like PF00682.19 KKK40902.1 - 5.4e-82 275.3 0.2 1.2e-81 274.2 0.1 1.6 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 KKK40902.1 - 3.7e-27 94.8 0.2 6.5e-27 94.0 0.2 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Aconitase PF00330.20 KKK40903.1 - 6.7e-91 305.6 0.1 1.6e-89 301.0 0.1 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK40904.1 - 1.4e-20 73.9 0.0 2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KKK40904.1 - 2.2e-05 24.2 0.0 0.0028 17.3 0.0 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus DUF640 PF04852.12 KKK40904.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Apolipoprotein PF01442.18 KKK40905.1 - 2.5e-11 43.8 20.5 5.3e-09 36.2 3.3 3.8 2 2 1 4 4 4 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KKK40905.1 - 0.0079 16.2 3.0 0.0079 16.2 3.0 6.1 3 2 3 6 6 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 KKK40905.1 - 0.0096 15.5 36.2 0.016 14.8 9.7 4.0 1 1 2 3 3 3 2 Exonuclease VII, large subunit TrmB PF01978.19 KKK40905.1 - 0.014 15.3 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF883 PF05957.13 KKK40905.1 - 0.051 14.2 15.8 5.2 7.7 1.7 5.8 3 2 5 8 8 8 0 Bacterial protein of unknown function (DUF883) Lant_dehydr_C PF14028.6 KKK40905.1 - 0.054 13.0 3.4 0.78 9.2 0.4 2.5 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term ApoLp-III PF07464.11 KKK40905.1 - 0.11 12.6 38.6 0.093 12.8 9.3 4.9 1 1 4 5 5 5 0 Apolipophorin-III precursor (apoLp-III) HSBP1 PF06825.12 KKK40905.1 - 0.14 12.0 3.7 5.3 7.0 0.1 4.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF842 PF05811.13 KKK40905.1 - 0.41 10.3 17.5 0.64 9.7 2.2 4.8 3 2 1 4 4 4 0 Eukaryotic protein of unknown function (DUF842) Pro_sub2 PF18513.1 KKK40905.1 - 0.92 9.7 5.6 0.38 11.0 0.1 3.3 3 1 0 3 3 3 0 Prodomain subtilisin 2 DUF885 PF05960.11 KKK40905.1 - 2.3 7.8 12.3 0.75 9.4 4.0 2.7 1 1 0 3 3 3 0 Bacterial protein of unknown function (DUF885) SATase_N PF06426.14 KKK40905.1 - 4.6 7.7 7.4 53 4.3 0.1 4.0 3 1 1 4 4 3 0 Serine acetyltransferase, N-terminal YtxH PF12732.7 KKK40905.1 - 4.6 7.8 25.4 1.8e+04 -16.3 25.2 7.0 1 1 0 1 1 0 0 YtxH-like protein Tape_meas_lam_C PF09718.10 KKK40905.1 - 4.7 7.4 9.1 1.1 9.5 0.1 4.1 5 0 0 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) eIF-5_eIF-2B PF01873.17 KKK40905.1 - 8.6 6.3 9.8 4.7 7.1 1.3 3.5 2 1 1 3 3 3 0 Domain found in IF2B/IF5 Prominin PF05478.11 KKK40905.1 - 9 4.1 44.3 0.042 11.8 19.0 2.4 1 1 0 2 2 2 0 Prominin DUF3240 PF11582.8 KKK40906.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) Rubrerythrin PF02915.17 KKK40908.1 - 1.4e-16 61.2 10.9 1.9e-16 60.7 10.9 1.2 1 0 0 1 1 1 1 Rubrerythrin Methyltransf_13 PF08421.11 KKK40908.1 - 0.0042 17.3 0.2 0.014 15.6 0.0 1.9 1 1 0 2 2 2 1 Putative zinc binding domain zf-ribbon_3 PF13248.6 KKK40908.1 - 0.0077 15.6 2.2 0.015 14.7 2.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KKK40908.1 - 0.14 12.3 1.4 0.48 10.6 1.5 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Cys_rich_CPCC PF14206.6 KKK40908.1 - 0.14 12.0 0.9 0.29 11.0 0.9 1.5 1 0 0 1 1 1 0 Cysteine-rich CPCC TF_Zn_Ribbon PF08271.12 KKK40908.1 - 0.21 11.1 1.6 12 5.5 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding UPF0547 PF10571.9 KKK40908.1 - 0.46 10.6 3.9 7.5 6.7 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RecR PF02132.15 KKK40908.1 - 0.67 9.6 5.2 0.36 10.4 2.7 1.9 2 0 0 2 2 2 0 RecR protein VIT1 PF01988.19 KKK40909.1 - 4e-59 200.1 3.4 4.5e-59 199.9 3.4 1.0 1 0 0 1 1 1 1 VIT family SLATT_1 PF18181.1 KKK40909.1 - 0.087 12.8 0.5 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2427 PF10348.9 KKK40909.1 - 2.7 7.8 6.9 0.87 9.4 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) OMPdecase PF00215.24 KKK40910.1 - 6.5e-12 45.5 0.3 7.6e-12 45.3 0.3 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribul_P_3_epim PF00834.19 KKK40910.1 - 0.0014 18.1 0.1 0.0025 17.2 0.1 1.5 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KKK40910.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.4 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Usp PF00582.26 KKK40910.1 - 0.032 14.7 0.2 0.046 14.2 0.2 1.3 1 0 0 1 1 1 0 Universal stress protein family PhoU PF01895.19 KKK40913.1 - 8.2e-11 42.2 2.9 1.3e-10 41.6 2.9 1.3 1 0 0 1 1 1 1 PhoU domain TrkA_C PF02080.21 KKK40913.1 - 0.0086 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-C domain SET PF00856.28 KKK40914.1 - 1.2e-15 58.3 2.0 1.1e-12 48.7 1.0 2.0 1 1 1 2 2 2 2 SET domain OMP_b-brl_3 PF14905.6 KKK40914.1 - 0.022 13.7 0.6 0.026 13.5 0.6 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family AP_endonuc_2 PF01261.24 KKK40916.1 - 6.1e-26 91.2 0.0 7.2e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2124 PF09897.9 KKK40916.1 - 0.0014 18.6 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) Ribosomal_L18_c PF14204.6 KKK40916.1 - 0.027 15.4 0.6 0.053 14.5 0.6 1.5 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region SelB-wing_2 PF09106.11 KKK40916.1 - 0.075 13.2 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 Elongation factor SelB, winged helix YwiC PF14256.6 KKK40917.1 - 0.43 10.9 13.2 0.17 12.2 4.4 2.2 1 1 1 2 2 2 0 YwiC-like protein MarR PF01047.22 KKK40918.1 - 2.3e-14 53.0 0.1 4.3e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KKK40918.1 - 2.8e-09 36.7 0.0 4.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KKK40918.1 - 3.2e-05 24.3 0.0 4.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 KKK40918.1 - 0.00042 20.1 0.0 0.001 18.9 0.0 1.6 1 1 1 2 2 2 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 KKK40918.1 - 0.0054 16.9 0.0 0.0087 16.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 KKK40918.1 - 0.0087 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 KKK40918.1 - 0.1 12.5 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HD_4 PF13328.6 KKK40919.1 - 3.9e-12 46.2 0.0 1.5e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 HD domain HD PF01966.22 KKK40919.1 - 1.2e-05 25.5 1.5 0.00014 22.0 1.5 2.1 1 1 0 1 1 1 1 HD domain DUF3574 PF12098.8 KKK40919.1 - 0.045 13.5 0.0 2.3 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) AmoC PF04896.12 KKK40919.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C HD_3 PF13023.6 KKK40919.1 - 0.18 11.7 2.4 0.48 10.3 2.3 1.7 1 1 0 1 1 1 0 HD domain HD_2 PF12917.7 KKK40919.1 - 0.21 11.3 2.1 5.5 6.7 1.9 2.2 1 1 0 1 1 1 0 HD containing hydrolase-like enzyme HSCB_C PF07743.13 KKK40920.1 - 0.021 15.3 1.0 0.07 13.6 1.0 1.9 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain RVT_2 PF07727.14 KKK40920.1 - 0.036 13.7 0.8 0.055 13.1 0.8 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) AFOR_C PF01314.18 KKK40921.1 - 5.1e-62 210.1 0.0 7.4e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK40921.1 - 1.1e-60 204.9 0.1 1.8e-60 204.2 0.1 1.3 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain HEPN PF05168.14 KKK40923.1 - 0.00013 22.1 0.1 0.00016 21.8 0.1 1.2 1 0 0 1 1 1 1 HEPN domain PI_PP_I PF18363.1 KKK40925.1 - 0.12 12.6 4.6 0.1 12.8 1.1 2.3 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain CODH_A_N PF18537.1 KKK40926.1 - 0.068 13.2 1.4 1.1 9.3 0.0 2.0 1 1 1 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain TFIIB PF00382.19 KKK40929.1 - 5.5e-28 96.8 0.1 1.2e-15 57.3 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat RB_B PF01857.20 KKK40929.1 - 0.00097 19.2 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Auto_anti-p27 PF06677.12 KKK40929.1 - 1 9.6 4.9 0.86 9.8 2.9 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pox_A9 PF04835.12 KKK40930.1 - 0.043 13.9 0.6 0.043 13.9 0.6 3.4 3 2 1 4 4 4 0 A9 protein conserved region Phage_holin_2_4 PF16082.5 KKK40930.1 - 3.6 7.4 5.2 24 4.8 0.2 2.6 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like DUF2371 PF10177.9 KKK40930.1 - 8 6.6 6.4 17 5.6 0.0 2.9 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) TF_Zn_Ribbon PF08271.12 KKK40931.1 - 2.4e-05 23.7 0.3 5e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 KKK40931.1 - 0.017 14.8 0.5 0.042 13.6 0.5 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain SNARE_assoc PF09335.11 KKK40932.1 - 4e-08 33.8 1.6 4e-08 33.8 1.6 3.1 3 1 1 4 4 4 1 SNARE associated Golgi protein DUF996 PF06195.13 KKK40932.1 - 0.011 16.1 7.3 0.011 16.1 7.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF996) E1-E2_ATPase PF00122.20 KKK40932.1 - 5.2 6.6 8.9 0.55 9.7 2.7 2.2 2 0 0 2 2 2 0 E1-E2 ATPase E1-E2_ATPase PF00122.20 KKK40933.1 - 3.6e-43 147.2 1.2 3.6e-43 147.2 1.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KKK40933.1 - 7.8e-20 70.8 0.1 1.5e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KKK40933.1 - 1.1e-18 68.3 0.0 2.7e-18 67.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KKK40933.1 - 2.2e-16 60.1 7.5 2.2e-16 60.1 7.5 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KKK40933.1 - 2.8e-11 42.9 0.0 6.6e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KKK40933.1 - 0.0017 18.1 8.4 0.0051 16.6 0.7 3.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4539 PF15072.6 KKK40933.1 - 0.012 15.7 0.2 0.056 13.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4539) E1-E2_ATPase PF00122.20 KKK40934.1 - 1e-46 158.8 5.0 4.5e-45 153.4 0.0 2.1 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 KKK40934.1 - 2.1e-14 52.9 1.6 6.8e-14 51.3 0.1 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2207 PF09972.9 KKK40934.1 - 0.024 13.4 8.9 0.075 11.8 0.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 KKK40934.1 - 2.1 7.9 4.7 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Wzy_C PF04932.15 KKK40934.1 - 7 6.3 8.8 0.86 9.2 0.3 2.2 2 0 0 2 2 2 0 O-Antigen ligase ABC_membrane PF00664.23 KKK40936.1 - 5.2e-40 137.8 20.6 7.1e-40 137.4 20.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK40936.1 - 1.7e-28 99.9 0.4 3.5e-28 98.8 0.4 1.6 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.17 KKK40936.1 - 0.0079 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KKK40936.1 - 0.028 14.3 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KKK40936.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KKK40936.1 - 0.051 14.1 0.1 0.38 11.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK40936.1 - 0.059 13.5 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Synaptobrevin PF00957.21 KKK40936.1 - 0.36 10.7 0.0 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Synaptobrevin ABC_membrane PF00664.23 KKK40937.1 - 2.3e-46 158.7 18.1 3e-46 158.3 18.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK40937.1 - 5.4e-34 117.6 0.2 1.1e-33 116.6 0.2 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane_3 PF13748.6 KKK40937.1 - 6.2e-05 22.4 10.7 0.035 13.3 10.1 3.2 2 1 0 2 2 2 1 ABC transporter transmembrane region DUF87 PF01935.17 KKK40937.1 - 0.00036 20.7 0.2 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain SMC_N PF02463.19 KKK40937.1 - 0.0012 18.3 4.0 0.037 13.5 4.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK40937.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_10 PF12846.7 KKK40937.1 - 0.01 14.8 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.18 KKK40937.1 - 0.024 14.0 0.2 0.06 12.7 0.1 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KKK40937.1 - 0.033 13.9 0.1 0.084 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK40937.1 - 0.035 14.5 0.1 0.083 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KKK40937.1 - 0.039 13.7 0.1 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.9 KKK40937.1 - 0.065 12.0 0.1 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF815 PF05673.13 KKK40937.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.29 KKK40937.1 - 0.14 11.9 0.4 0.87 9.3 0.4 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase DDE_Tnp_1 PF01609.21 KKK40938.1 - 2.2e-08 34.0 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DUF2207 PF09972.9 KKK40939.1 - 3.4 6.3 11.2 1.1 7.9 0.9 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Plant_vir_prot PF01307.17 KKK40939.1 - 5.5 7.3 5.3 2 8.7 0.2 2.5 1 1 2 3 3 3 0 Plant viral movement protein Sdh_cyt PF01127.22 KKK40939.1 - 6.2 6.9 11.8 3.2 7.8 1.7 2.4 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit HypD PF01924.16 KKK40943.1 - 4.7e-62 210.1 0.0 5.3e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family AIRS_C PF02769.22 KKK40944.1 - 3.6e-27 95.4 0.0 5.1e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KKK40944.1 - 6.8e-15 55.5 0.5 1.6e-14 54.3 0.5 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Oxidored_q6 PF01058.22 KKK40945.1 - 0.00058 19.7 0.0 0.00066 19.5 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Radical_SAM PF04055.21 KKK40949.1 - 1.3e-09 38.7 0.3 2.8e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily BPL_LplA_LipB PF03099.19 KKK40950.1 - 8.3e-09 35.4 0.0 2.3e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Radical_SAM PF04055.21 KKK40951.1 - 1.2e-13 51.8 0.2 2e-13 51.1 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KKK40951.1 - 0.00067 19.8 0.9 0.0013 18.9 0.2 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain BATS PF06968.13 KKK40951.1 - 0.022 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain PEP_hydrolase PF09370.10 KKK40951.1 - 0.076 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like F420_ligase PF01996.16 KKK40952.1 - 3.3e-61 206.7 0.7 4.7e-61 206.2 0.7 1.1 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Nitroreductase PF00881.24 KKK40952.1 - 2.6e-21 76.4 0.0 7.1e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK40952.1 - 1.4e-05 24.8 0.0 0.0022 17.6 0.0 2.5 2 0 0 2 2 2 2 Putative TM nitroreductase DUF2624 PF11116.8 KKK40952.1 - 0.063 14.2 0.3 0.24 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) UPF0052 PF01933.18 KKK40953.1 - 2.1e-41 142.1 0.0 2.7e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DNA_pol_D_N PF18018.1 KKK40954.1 - 0.054 13.6 0.6 0.12 12.4 0.5 1.6 1 1 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain MDM10 PF12519.8 KKK40954.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DUF2205 PF10224.9 KKK40954.1 - 4.2 7.4 6.5 2.7 8.0 1.8 2.5 2 1 0 2 2 2 0 Short coiled-coil protein DUF58 PF01882.18 KKK40955.1 - 3e-23 81.9 0.0 5.1e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 KKK40955.1 - 9.5e-10 39.1 0.0 2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KKK40955.1 - 0.0015 18.0 0.0 0.0045 16.4 0.0 1.8 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.28 KKK40955.1 - 0.0071 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain TRAP_beta PF05753.14 KKK40955.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) AAA_lid_2 PF17863.1 KKK40956.1 - 2.3e-20 72.2 0.0 3.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 AAA lid domain SBP_bac_5 PF00496.22 KKK40959.1 - 4e-21 75.4 21.8 7.2e-20 71.3 21.8 2.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KKK40960.1 - 9.4e-35 120.0 2.4 9.4e-35 120.0 2.4 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2157 PF09925.9 KKK40960.1 - 0.66 9.8 4.0 5.1 6.9 0.1 2.9 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) DUF3930 PF13067.6 KKK40960.1 - 1.3 9.3 4.0 15 6.0 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) BPD_transp_1 PF00528.22 KKK40961.1 - 6.8e-28 97.7 12.6 6.8e-28 97.7 12.6 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component T2SSF PF00482.23 KKK40961.1 - 1.3 9.0 4.4 0.64 10.0 0.1 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F ABC_tran PF00005.27 KKK40962.1 - 4.7e-26 91.9 0.0 8.2e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KKK40962.1 - 2.8e-18 66.2 0.2 4.7e-18 65.5 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region ResIII PF04851.15 KKK40962.1 - 0.0012 18.9 0.8 0.027 14.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA PF00004.29 KKK40962.1 - 0.019 15.4 0.5 8.3 6.8 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RhodobacterPufX PF11511.8 KKK40962.1 - 6.5 6.4 8.9 6.6 6.4 0.0 4.2 3 1 1 4 4 4 0 Intrinsic membrane protein PufX ABC_tran PF00005.27 KKK40963.1 - 5.1e-34 117.7 0.0 7.7e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KKK40963.1 - 2.2e-14 53.7 0.1 3.7e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KKK40963.1 - 1.7e-09 37.9 0.3 9.3e-07 28.9 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK40963.1 - 1.6e-08 34.3 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK40963.1 - 0.00039 20.7 0.2 0.0021 18.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KKK40963.1 - 0.0019 17.8 0.0 0.0049 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK40963.1 - 0.0034 17.8 0.0 0.0069 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 KKK40963.1 - 0.0044 16.8 0.2 0.36 10.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 KKK40963.1 - 0.015 15.3 0.0 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) tRNA_lig_kinase PF08303.11 KKK40963.1 - 0.026 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA PF00004.29 KKK40963.1 - 0.028 14.9 0.9 0.34 11.3 0.9 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK40963.1 - 0.072 12.8 0.1 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_13 PF13166.6 KKK40963.1 - 0.075 11.7 0.0 0.18 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK40963.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 KKK40963.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 KKK40963.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KKK40963.1 - 0.13 12.5 0.0 0.62 10.3 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 KKK40963.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 KKK40963.1 - 0.39 9.9 1.3 1.1 8.3 1.3 1.8 1 1 0 1 1 1 0 NB-ARC domain CENP-H PF05837.12 KKK40964.1 - 0.19 12.2 0.1 0.19 12.2 0.1 3.7 5 0 0 5 5 5 0 Centromere protein H (CENP-H) LIM PF00412.22 KKK40965.1 - 0.00038 20.6 1.7 0.00044 20.4 1.7 1.1 1 0 0 1 1 1 1 LIM domain zinc_ribbon_2 PF13240.6 KKK40965.1 - 1.3 8.8 7.0 55 3.7 7.0 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Cwf_Cwc_15 PF04889.12 KKK40965.1 - 5.3 6.7 12.6 5 6.8 12.6 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GATase PF00117.28 KKK40966.1 - 1.4e-42 145.7 0.1 1.8e-42 145.2 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.14 KKK40966.1 - 1.6e-33 116.2 0.0 2.4e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.13 KKK40966.1 - 9.3e-11 41.9 0.1 3e-10 40.2 0.0 1.9 1 1 1 2 2 2 1 Peptidase C26 zinc_ribbon_10 PF10058.9 KKK40970.1 - 0.00061 19.5 0.3 0.0012 18.5 0.3 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 KKK40970.1 - 0.00096 19.1 0.1 0.0012 18.8 0.1 1.3 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIE_alpha PF02002.17 KKK40970.1 - 0.0041 17.0 3.3 0.005 16.7 0.7 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KKK40970.1 - 0.0042 16.6 3.2 0.012 15.1 2.9 1.9 1 1 1 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KKK40970.1 - 0.0045 17.1 1.0 0.0095 16.0 1.0 1.5 1 0 0 1 1 1 1 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 KKK40970.1 - 0.0051 16.7 0.7 0.0051 16.7 0.7 1.4 2 0 0 2 2 2 1 Domain found in IF2B/IF5 DNA_ligase_ZBD PF03119.16 KKK40970.1 - 0.0061 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain E6 PF00518.17 KKK40970.1 - 0.017 15.5 0.3 0.063 13.7 0.2 1.7 1 1 1 2 2 2 0 Early Protein (E6) zf-Mss51 PF13824.6 KKK40970.1 - 0.034 14.3 1.0 0.062 13.4 0.8 1.7 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ISL3 PF14690.6 KKK40970.1 - 0.036 14.7 0.4 0.49 11.1 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rad50_zn_hook PF04423.14 KKK40970.1 - 0.038 13.8 1.5 0.053 13.4 0.0 2.0 3 0 0 3 3 3 0 Rad50 zinc hook motif Auto_anti-p27 PF06677.12 KKK40970.1 - 0.039 14.1 1.0 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc-ribbons_6 PF07191.12 KKK40970.1 - 0.039 13.9 0.6 0.074 13.1 0.6 1.4 1 1 0 1 1 1 0 zinc-ribbons DZR PF12773.7 KKK40970.1 - 0.048 13.7 1.0 0.092 12.8 1.0 1.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK40970.1 - 0.055 12.9 2.7 0.18 11.2 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF3725 PF12523.8 KKK40970.1 - 0.076 13.3 0.7 0.076 13.3 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3725) Mcm10 PF09332.11 KKK40970.1 - 0.13 11.7 0.9 0.19 11.1 0.9 1.2 1 0 0 1 1 1 0 Mcm10 replication factor zinc_ribbon_4 PF13717.6 KKK40970.1 - 5.8 6.9 7.4 1.6e+02 2.3 7.4 2.8 1 1 0 1 1 1 0 zinc-ribbon domain HTH_3 PF01381.22 KKK40971.1 - 4.2e-09 36.3 0.7 7e-09 35.6 0.7 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KKK40971.1 - 0.0075 16.6 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 KKK40971.1 - 0.015 15.4 0.8 0.046 13.8 0.8 1.8 1 1 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_19 PF12844.7 KKK40971.1 - 0.028 14.4 1.5 0.037 14.1 1.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HIRA_B PF09453.10 KKK40972.1 - 3.2 7.7 4.7 7.6 6.5 2.6 2.1 2 0 0 2 2 2 0 HIRA B motif Radical_SAM PF04055.21 KKK40974.1 - 2.5e-17 63.7 0.1 4.1e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 KKK40974.1 - 6.9e-17 61.3 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 zinc_ribbon_15 PF17032.5 KKK40975.1 - 2e-06 28.5 5.6 0.00071 20.3 2.1 2.4 2 1 0 2 2 2 2 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK40975.1 - 2.2e-05 23.7 0.9 2.2e-05 23.7 0.9 2.3 3 0 0 3 3 2 1 zinc-ribbon domain DZR PF12773.7 KKK40975.1 - 4.6e-05 23.4 6.3 0.013 15.5 1.6 3.0 2 1 1 3 3 3 2 Double zinc ribbon Prok-RING_4 PF14447.6 KKK40975.1 - 0.0009 19.0 8.2 0.0041 17.0 1.0 3.1 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KKK40975.1 - 0.002 18.0 9.1 0.02 14.7 1.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 KKK40975.1 - 0.009 15.7 3.1 0.009 15.7 3.1 2.5 3 0 0 3 3 2 1 zinc-ribbon domain zf-BED PF02892.15 KKK40975.1 - 0.018 15.0 11.9 0.27 11.3 2.5 3.7 3 1 0 3 3 3 0 BED zinc finger zinc-ribbons_6 PF07191.12 KKK40975.1 - 0.026 14.5 9.8 0.081 12.9 2.0 2.9 2 1 0 2 2 2 0 zinc-ribbons E3_UbLigase_R4 PF13764.6 KKK40975.1 - 0.046 11.9 0.5 0.063 11.4 0.5 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 zf-LITAF-like PF10601.9 KKK40975.1 - 0.048 13.9 6.4 0.54 10.6 0.1 2.8 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain zf-RING_5 PF14634.6 KKK40975.1 - 0.055 13.4 11.2 0.14 12.1 2.1 3.2 3 0 0 3 3 3 0 zinc-RING finger domain Yippee-Mis18 PF03226.14 KKK40975.1 - 0.066 13.4 2.9 0.15 12.2 1.0 2.2 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_10 PF16588.5 KKK40975.1 - 0.071 12.9 2.0 0.071 12.9 2.0 3.3 4 1 0 4 4 4 0 C2H2 zinc-finger zf-Di19 PF05605.12 KKK40975.1 - 0.087 13.1 8.8 7.8 6.9 0.1 4.0 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding VKOR PF07884.14 KKK40975.1 - 0.087 13.0 0.5 0.087 13.0 0.5 1.8 2 0 0 2 2 2 0 Vitamin K epoxide reductase family TF_Zn_Ribbon PF08271.12 KKK40975.1 - 0.11 12.0 8.0 0.35 10.4 0.2 3.4 2 1 1 3 3 3 0 TFIIB zinc-binding zf-RING_2 PF13639.6 KKK40975.1 - 0.17 12.3 5.6 9.4 6.7 0.6 3.2 3 0 0 3 3 3 0 Ring finger domain A2L_zn_ribbon PF08792.10 KKK40975.1 - 0.21 11.4 10.3 1.2 9.0 4.4 3.1 2 1 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.22 KKK40975.1 - 0.31 11.0 8.3 4.5 7.2 1.3 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sgf11 PF08209.11 KKK40975.1 - 0.51 9.9 4.0 2.9 7.5 0.1 3.1 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-C3HC4_2 PF13923.6 KKK40975.1 - 0.63 9.9 8.2 9.8 6.1 1.3 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) BIR PF00653.21 KKK40975.1 - 0.71 10.6 10.2 29 5.4 3.6 4.0 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain Prok-RING_1 PF14446.6 KKK40975.1 - 0.73 9.8 9.2 0.68 9.9 1.4 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 KKK40975.1 - 0.74 10.2 9.1 0.56 10.6 1.6 2.9 3 0 0 3 3 3 0 C1 domain DUF3797 PF12677.7 KKK40975.1 - 0.75 9.7 0.2 0.75 9.7 0.2 2.8 3 1 0 3 3 2 0 Domain of unknown function (DUF3797) zinc_ribbon_9 PF14369.6 KKK40975.1 - 0.9 9.9 5.1 5.3 7.4 0.3 3.2 2 1 1 3 3 3 0 zinc-ribbon HypA PF01155.19 KKK40975.1 - 1.2 9.1 9.7 0.37 10.8 1.7 2.3 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Phage_Gp23 PF10669.9 KKK40975.1 - 1.7 9.0 7.5 0.72 10.2 4.5 1.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) RecR PF02132.15 KKK40975.1 - 2.5 7.7 8.9 5.9 6.5 1.5 3.1 3 0 0 3 3 3 0 RecR protein zf-C3HC4 PF00097.25 KKK40975.1 - 2.7 8.0 8.3 28 4.7 1.7 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Cytochrom_c3_2 PF14537.6 KKK40975.1 - 4.4 7.9 8.0 1.9e+02 2.6 0.2 2.6 1 1 1 2 2 2 0 Cytochrome c3 HTH_24 PF13412.6 KKK40976.1 - 2e-05 24.0 0.1 4.1e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 KKK40976.1 - 0.0021 17.9 0.1 0.0038 17.1 0.1 1.5 1 0 0 1 1 1 1 HTH domain GerE PF00196.19 KKK40976.1 - 0.0028 17.2 0.2 0.0046 16.5 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TnsD PF15978.5 KKK40976.1 - 0.0091 15.0 0.8 0.011 14.7 0.6 1.3 1 1 0 1 1 1 1 Tn7-like transposition protein D Homeodomain PF00046.29 KKK40976.1 - 0.011 15.6 0.1 0.58 10.0 0.0 2.3 1 1 1 2 2 2 0 Homeodomain Terminase_5 PF06056.12 KKK40976.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF2582 PF10771.9 KKK40976.1 - 0.02 15.1 0.6 0.064 13.4 0.2 2.1 2 1 0 2 2 2 0 Winged helix-turn-helix domain (DUF2582) DUF4423 PF14394.6 KKK40976.1 - 0.021 14.5 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF3489 PF11994.8 KKK40976.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Sigma70_r4_2 PF08281.12 KKK40976.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.19 KKK40976.1 - 0.091 12.7 1.4 0.28 11.1 1.4 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 KKK40976.1 - 0.092 13.4 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal DUF4761 PF15958.5 KKK40976.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) HTH_29 PF13551.6 KKK40976.1 - 0.19 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_10 PF04967.12 KKK40976.1 - 0.39 10.6 1.9 0.42 10.4 0.1 2.0 3 0 0 3 3 3 0 HTH DNA binding domain SASP PF00269.20 KKK40977.1 - 0.13 12.3 0.2 2.1 8.4 0.0 2.1 1 1 1 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type DNA_mis_repair PF01119.19 KKK40979.1 - 2.3e-18 66.0 0.0 4.9e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KKK40979.1 - 3.8e-14 52.7 0.2 6.2e-14 52.0 0.2 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK40979.1 - 4.4e-10 40.1 0.4 1e-09 38.9 0.4 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ADH_zinc_N_2 PF13602.6 KKK40982.1 - 1.4e-26 94.2 0.0 2.1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK40982.1 - 1.5e-15 57.3 0.0 3.3e-15 56.2 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK40982.1 - 2e-08 34.1 0.0 4.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KKK40982.1 - 0.00074 18.9 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MAF_flag10 PF01973.18 KKK40982.1 - 0.039 13.6 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF115 DUF4760 PF15956.5 KKK40983.1 - 0.00017 21.7 0.2 0.0002 21.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4760) HARP PF07443.13 KKK40983.1 - 0.098 12.3 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 HepA-related protein (HARP) Amidohydro_3 PF07969.11 KKK40984.1 - 6.6e-21 75.3 0.0 7.2e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KKK40984.1 - 1e-07 31.6 0.0 1e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family TetR_N PF00440.23 KKK40986.1 - 6.8e-13 48.2 1.2 1.4e-12 47.2 1.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_11 PF08279.12 KKK40986.1 - 9.3e-05 22.3 0.1 0.022 14.7 0.0 3.3 3 0 0 3 3 3 1 HTH domain HTH_Tnp_1_2 PF13022.6 KKK40986.1 - 0.00078 19.6 0.2 0.0017 18.5 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 KKK40986.1 - 0.0016 18.2 0.2 0.025 14.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KKK40986.1 - 0.02 15.0 1.3 0.086 12.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_22 PF13309.6 KKK40986.1 - 0.02 14.9 0.1 0.068 13.3 0.1 2.0 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 KKK40986.1 - 0.071 13.1 0.3 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 KKK40986.1 - 0.1 12.7 0.0 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix Flavodoxin_5 PF12724.7 KKK40987.1 - 4e-09 36.9 0.0 5.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 KKK40987.1 - 2.2e-08 34.0 0.0 2.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Amidohydro_3 PF07969.11 KKK40988.1 - 1.1e-92 312.0 0.0 1.3e-92 311.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KKK40988.1 - 6.9e-16 58.5 0.0 3.3e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Peptidase_S9 PF00326.21 KKK40989.1 - 2e-10 40.5 0.0 3.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KKK40989.1 - 2.2e-09 37.0 0.1 1.1e-06 28.2 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK40989.1 - 2.4e-06 27.4 0.1 5e-06 26.3 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KKK40989.1 - 2.5e-06 27.3 0.0 4.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KKK40989.1 - 1.9e-05 23.5 0.0 0.095 11.4 0.0 3.2 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 KKK40989.1 - 5.6e-05 22.8 0.0 0.00061 19.4 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 KKK40989.1 - 0.00014 21.6 0.0 0.00037 20.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKK40989.1 - 0.0063 17.2 0.0 0.0092 16.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2180 PF09947.9 KKK40990.1 - 0.003 17.5 6.0 0.006 16.5 6.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2180) zf-AN1 PF01428.16 KKK40990.1 - 0.015 15.5 11.1 0.41 10.9 6.2 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger C5HCH PF17982.1 KKK40990.1 - 0.024 14.8 10.5 0.089 13.0 10.8 1.7 1 1 1 2 2 2 0 NSD Cys-His rich domain DUF2321 PF10083.9 KKK40990.1 - 0.031 13.9 2.1 0.033 13.8 2.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Viral_Beta_CD PF04530.12 KKK40990.1 - 0.072 13.4 0.8 0.1 12.9 0.8 1.2 1 0 0 1 1 1 0 Viral Beta C/D like family Tnp_zf-ribbon_2 PF13842.6 KKK40990.1 - 0.094 13.5 11.0 0.55 11.1 4.9 2.6 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon YukC PF10140.9 KKK40990.1 - 0.12 11.2 0.1 0.13 11.1 0.1 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC NOA36 PF06524.12 KKK40990.1 - 0.13 11.5 4.7 0.14 11.5 4.7 1.0 1 0 0 1 1 1 0 NOA36 protein zf-ribbon_3 PF13248.6 KKK40990.1 - 0.2 11.1 9.5 2.4 7.7 0.2 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zf-HYPF PF07503.12 KKK40990.1 - 0.37 10.6 0.2 0.37 10.6 0.2 2.9 1 1 2 3 3 3 0 HypF finger Transp_Tc5_C PF04236.15 KKK40990.1 - 0.54 10.7 10.5 0.15 12.4 5.0 2.1 1 1 1 2 2 2 0 Tc5 transposase C-terminal domain Sigma_reg_N PF13800.6 KKK40990.1 - 0.61 10.4 4.7 0.75 10.1 4.7 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal C1_1 PF00130.22 KKK40990.1 - 0.78 9.7 9.3 16 5.5 9.5 2.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-B_box PF00643.24 KKK40990.1 - 1.3 9.2 9.5 1.3 9.3 4.9 2.1 2 0 0 2 2 2 0 B-box zinc finger DUF2116 PF09889.9 KKK40990.1 - 1.5 8.9 8.6 0.29 11.2 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) FYVE PF01363.21 KKK40990.1 - 8.8 6.5 12.1 12 6.1 0.5 2.4 1 1 1 2 2 2 0 FYVE zinc finger 4HBT PF03061.22 KKK40991.1 - 4.5e-16 59.0 0.3 7.7e-16 58.2 0.3 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Cupin_2 PF07883.11 KKK40992.1 - 0.00017 21.2 0.0 0.0002 21.0 0.0 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KKK40992.1 - 0.058 13.3 0.0 0.076 12.9 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain CBM32 PF18344.1 KKK40992.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module family 32 Radical_SAM PF04055.21 KKK40993.1 - 7.9e-19 68.6 0.1 1.4e-18 67.9 0.1 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK40993.1 - 4.4e-13 49.7 0.2 1e-12 48.5 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK40993.1 - 2e-11 44.1 0.5 3.9e-11 43.1 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain PfkB PF00294.24 KKK40994.1 - 6.7e-07 28.9 0.0 7.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KKK40994.1 - 0.021 14.2 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF4364 PF14277.6 KKK40996.1 - 0.0031 17.3 0.3 0.0034 17.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_45 PF14947.6 KKK40996.1 - 0.0036 17.2 2.0 0.0036 17.2 2.0 1.9 1 1 0 2 2 2 1 Winged helix-turn-helix DUF1495 PF07381.11 KKK40996.1 - 0.0084 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) Lactamase_B PF00753.27 KKK40997.1 - 1.9e-22 80.3 0.1 1.1e-21 77.7 0.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK40997.1 - 0.00085 18.9 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK40998.1 - 5.5e-16 59.2 0.5 4.6e-15 56.2 0.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK40998.1 - 0.0051 16.3 0.1 0.0081 15.7 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK40998.1 - 0.034 14.0 0.0 0.039 13.8 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF72 PF01904.18 KKK41003.1 - 1.2e-44 153.0 1.2 1.4e-44 152.8 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 Clat_adaptor_s PF01217.20 KKK41003.1 - 0.042 13.8 1.1 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Clathrin adaptor complex small chain APG12 PF04110.13 KKK41003.1 - 0.067 13.6 0.1 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 FPP PF05911.11 KKK41004.1 - 0.0036 15.6 16.6 0.0036 15.6 16.6 2.0 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 KKK41004.1 - 0.0037 17.3 18.7 0.0037 17.3 18.7 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KKK41004.1 - 0.13 12.7 31.1 0.66 10.4 17.1 2.6 1 1 1 2 2 2 0 Fez1 Filament PF00038.21 KKK41004.1 - 0.23 11.0 35.1 1.3 8.6 34.5 2.0 1 1 0 1 1 1 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 KKK41004.1 - 0.42 10.7 31.0 0.029 14.4 15.9 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 KKK41004.1 - 0.72 9.3 31.3 6.8 6.1 31.1 2.1 1 1 0 1 1 1 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 KKK41004.1 - 1.5 9.0 28.9 2.3 8.4 11.2 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.6 KKK41004.1 - 1.6 9.1 29.6 10 6.6 6.5 3.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Lebercilin PF15619.6 KKK41004.1 - 1.7 8.3 37.2 9.1 5.9 28.3 2.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Csm1_N PF18504.1 KKK41004.1 - 2.5 8.5 33.4 0.34 11.3 3.3 4.7 1 1 2 4 4 4 0 Csm1 N-terminal domain Spc7 PF08317.11 KKK41004.1 - 2.5 6.9 36.9 0.045 12.6 17.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Synaptonemal_3 PF15191.6 KKK41004.1 - 2.8 7.8 7.8 0.61 9.9 0.7 2.8 1 1 2 3 3 3 0 Synaptonemal complex central element protein 3 SlyX PF04102.12 KKK41004.1 - 4.5 8.0 18.5 6.1 7.5 1.7 4.2 2 1 2 4 4 4 0 SlyX Atg14 PF10186.9 KKK41004.1 - 6.4 5.8 36.8 1.4 7.9 9.7 2.3 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KKK41004.1 - 8.3 6.9 32.7 0.12 12.8 15.5 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 KKK41004.1 - 9.7 6.6 32.1 47 4.4 15.1 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 KKK41005.1 - 7.8e-06 25.9 27.5 0.0023 18.0 12.1 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF1664) Spc7 PF08317.11 KKK41005.1 - 1.8e-05 23.8 46.0 0.00053 19.0 32.5 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 KKK41005.1 - 4.1e-05 23.0 45.6 0.00038 19.9 24.5 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 KKK41005.1 - 0.00018 19.2 31.5 0.00023 18.9 31.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 KKK41005.1 - 0.00023 21.4 33.2 0.0092 16.2 16.6 2.5 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KKK41005.1 - 0.00051 20.6 38.4 0.063 13.7 9.5 2.2 1 1 1 2 2 2 2 Fez1 Bacillus_HBL PF05791.11 KKK41005.1 - 0.00062 19.6 27.3 0.0015 18.4 6.0 2.6 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) APG6_N PF17675.1 KKK41005.1 - 0.00087 19.8 47.7 0.0063 17.0 29.7 3.0 1 1 2 3 3 3 1 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KKK41005.1 - 0.00099 19.2 42.3 0.013 15.6 7.0 3.7 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 KKK41005.1 - 0.0011 19.4 32.0 0.53 10.9 3.7 3.5 1 1 3 4 4 4 2 Syntaxin 6, N-terminal DUF3450 PF11932.8 KKK41005.1 - 0.0018 17.7 32.5 0.0038 16.6 7.6 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) DUF4795 PF16043.5 KKK41005.1 - 0.0026 17.4 41.1 0.051 13.2 41.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) ADIP PF11559.8 KKK41005.1 - 0.0031 17.6 43.1 0.31 11.1 20.9 3.5 1 1 3 4 4 3 2 Afadin- and alpha -actinin-Binding Tektin PF03148.14 KKK41005.1 - 0.0031 16.3 36.4 0.018 13.8 12.7 3.5 1 1 2 3 3 3 1 Tektin family DUF948 PF06103.11 KKK41005.1 - 0.0053 17.0 20.4 0.24 11.7 1.8 3.4 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF948) Vps51 PF08700.11 KKK41005.1 - 0.0058 16.7 27.4 1.1 9.4 7.8 5.1 1 1 1 2 2 2 1 Vps51/Vps67 DUF4200 PF13863.6 KKK41005.1 - 0.0064 16.9 21.5 0.0064 16.9 21.5 3.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) HSBP1 PF06825.12 KKK41005.1 - 0.0085 15.9 13.0 2.6 8.0 0.3 5.1 5 0 0 5 5 5 0 Heat shock factor binding protein 1 WXG100 PF06013.12 KKK41005.1 - 0.0089 16.2 10.1 0.59 10.4 0.5 4.2 3 1 0 3 3 3 1 Proteins of 100 residues with WXG MAD PF05557.13 KKK41005.1 - 0.0098 14.3 42.9 0.044 12.2 42.9 1.8 1 1 0 1 1 1 1 Mitotic checkpoint protein YscO-like PF16789.5 KKK41005.1 - 0.0098 15.9 13.4 0.0098 15.9 13.4 2.5 1 1 1 2 2 2 1 YscO-like protein DivIC PF04977.15 KKK41005.1 - 0.01 15.6 39.6 0.015 15.0 1.7 5.2 1 1 3 4 4 3 0 Septum formation initiator EcsC PF12787.7 KKK41005.1 - 0.016 14.9 2.6 0.024 14.3 1.0 2.1 1 1 0 1 1 1 0 EcsC protein family MIP-T3_C PF17749.1 KKK41005.1 - 0.017 15.1 30.4 1.4 8.9 9.0 3.7 1 1 3 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region HIP1_clath_bdg PF16515.5 KKK41005.1 - 0.019 15.6 37.2 1.3 9.7 13.8 3.7 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Golgin_A5 PF09787.9 KKK41005.1 - 0.022 14.2 40.9 0.15 11.5 21.9 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 AAA_13 PF13166.6 KKK41005.1 - 0.022 13.4 35.0 0.48 9.0 7.9 2.3 1 1 1 2 2 2 0 AAA domain Nup54 PF13874.6 KKK41005.1 - 0.024 14.7 21.9 0.76 9.9 17.4 3.1 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 CENP-F_leu_zip PF10473.9 KKK41005.1 - 0.027 14.5 51.0 0.025 14.6 22.9 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 KKK41005.1 - 0.029 14.4 22.1 0.41 10.7 6.8 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 KKK41005.1 - 0.033 13.8 38.0 0.11 12.1 38.0 2.3 1 1 0 1 1 1 0 Intermediate filament protein COG2 PF06148.11 KKK41005.1 - 0.035 14.2 28.4 0.51 10.4 4.6 4.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Ax_dynein_light PF10211.9 KKK41005.1 - 0.036 14.0 44.2 0.32 10.9 11.2 3.5 1 1 2 3 3 3 0 Axonemal dynein light chain Lebercilin PF15619.6 KKK41005.1 - 0.045 13.4 42.0 0.63 9.7 25.9 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease zf-C4H2 PF10146.9 KKK41005.1 - 0.049 13.9 38.8 0.17 12.2 10.0 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein DUF4618 PF15397.6 KKK41005.1 - 0.055 12.9 35.5 0.62 9.4 15.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 KKK41005.1 - 0.058 13.9 20.4 2 8.9 2.9 4.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COMP PF11598.8 KKK41005.1 - 0.06 13.8 10.5 0.4 11.2 0.5 3.9 4 1 1 5 5 2 0 Cartilage oligomeric matrix protein SlyX PF04102.12 KKK41005.1 - 0.06 14.0 20.4 3.9 8.2 0.8 4.4 1 1 3 4 4 4 0 SlyX Tropomyosin_1 PF12718.7 KKK41005.1 - 0.074 13.2 53.2 1.1 9.4 4.7 3.5 1 1 2 3 3 3 0 Tropomyosin like HMMR_N PF15905.5 KKK41005.1 - 0.079 12.4 49.9 0.66 9.4 31.9 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 KKK41005.1 - 0.079 13.0 62.5 0.14 12.2 17.8 5.2 2 1 2 5 5 4 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 KKK41005.1 - 0.11 12.7 41.4 14 6.0 7.1 4.2 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) ApoO PF09769.9 KKK41005.1 - 0.12 12.3 9.6 1.5 8.8 0.8 3.4 1 1 1 3 3 3 0 Apolipoprotein O FapA PF03961.13 KKK41005.1 - 0.12 10.9 37.8 0.17 10.4 22.3 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Tropomyosin PF00261.20 KKK41005.1 - 0.15 11.4 45.9 0.69 9.2 45.6 1.9 1 1 0 1 1 1 0 Tropomyosin Rab5-bind PF09311.11 KKK41005.1 - 0.15 11.4 37.4 6.2 6.1 14.9 2.3 1 1 1 2 2 2 0 Rabaptin-like protein DUF724 PF05266.14 KKK41005.1 - 0.2 11.5 41.9 0.14 12.0 19.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) HemX PF04375.14 KKK41005.1 - 0.23 10.7 25.4 0.45 9.7 10.4 2.7 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Phage_GP20 PF06810.11 KKK41005.1 - 0.23 11.2 40.7 0.36 10.6 6.4 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 ERM PF00769.19 KKK41005.1 - 0.29 10.9 40.2 0.5 10.1 24.1 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2968 PF11180.8 KKK41005.1 - 0.29 10.7 20.0 0.065 12.9 6.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) LXG PF04740.12 KKK41005.1 - 0.51 10.0 26.5 16 5.1 20.0 3.3 1 1 1 2 2 2 0 LXG domain of WXG superfamily DLP_helical PF18709.1 KKK41005.1 - 0.55 9.4 30.0 1.3 8.1 2.1 3.2 1 1 2 3 3 3 0 Dynamin-like helical domain CALCOCO1 PF07888.11 KKK41005.1 - 0.57 9.0 42.0 0.91 8.3 32.2 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4201 PF13870.6 KKK41005.1 - 0.59 9.8 41.7 0.33 10.7 19.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) KxDL PF10241.9 KKK41005.1 - 0.69 10.2 23.7 0.14 12.4 3.8 4.2 1 1 2 3 3 3 0 Uncharacterized conserved protein ATG16 PF08614.11 KKK41005.1 - 0.71 10.1 40.5 5.7 7.1 5.2 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF16 PF01519.16 KKK41005.1 - 0.79 10.2 35.9 11 6.6 5.0 3.9 1 1 1 2 2 1 0 Protein of unknown function DUF16 Flagellin_C PF00700.21 KKK41005.1 - 0.88 10.0 9.6 1.6 9.2 1.0 3.4 2 1 0 3 3 3 0 Bacterial flagellin C-terminal helical region LPP PF04728.13 KKK41005.1 - 0.9 10.0 17.4 3.5 8.1 0.4 5.1 2 2 3 5 5 5 0 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.22 KKK41005.1 - 0.98 9.7 46.7 3.1 8.1 2.0 4.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FPP PF05911.11 KKK41005.1 - 1.1 7.3 43.7 0.11 10.6 24.2 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Atg14 PF10186.9 KKK41005.1 - 1.2 8.2 42.6 0.24 10.5 10.7 2.6 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 KKK41005.1 - 1.3 9.4 33.1 3.7 7.9 2.3 4.8 2 1 3 5 5 3 0 Tup N-terminal Lectin_N PF03954.14 KKK41005.1 - 1.5 8.6 21.0 1.2 8.9 1.5 3.3 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain IFT57 PF10498.9 KKK41005.1 - 1.6 7.6 36.6 1.3 7.9 7.5 2.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 UPF0449 PF15136.6 KKK41005.1 - 1.8 9.1 30.6 0.3 11.6 1.8 4.7 2 2 1 4 4 4 0 Uncharacterised protein family UPF0449 Prefoldin_2 PF01920.20 KKK41005.1 - 1.8 8.6 53.1 7 6.7 11.5 6.0 1 1 5 6 6 6 0 Prefoldin subunit Prominin PF05478.11 KKK41005.1 - 1.9 6.4 24.8 3.9 5.3 24.8 1.5 1 1 0 1 1 1 0 Prominin GIT_CC PF16559.5 KKK41005.1 - 2.1 8.3 20.1 0.34 10.8 3.1 4.0 2 2 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1729 PF08354.10 KKK41005.1 - 2.4 7.0 9.1 0.46 9.3 0.7 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF1729) Vps54_N PF10475.9 KKK41005.1 - 2.4 7.4 25.0 0.6 9.3 6.8 2.4 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex PI3K_P85_iSH2 PF16454.5 KKK41005.1 - 2.5 7.7 37.5 4.6 6.8 16.4 3.7 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 KKK41005.1 - 2.7 7.3 25.6 52 3.0 25.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PI_PP_I PF18363.1 KKK41005.1 - 2.9 8.2 9.5 8.2 6.7 1.8 2.9 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain COG5 PF10392.9 KKK41005.1 - 3 8.0 24.9 14 5.8 2.9 3.7 1 1 0 2 2 2 0 Golgi transport complex subunit 5 BRI3BP PF14965.6 KKK41005.1 - 3.1 7.3 4.2 1.7 8.1 1.1 2.2 2 0 0 2 2 1 0 Negative regulator of p53/TP53 HAUS-augmin3 PF14932.6 KKK41005.1 - 3.2 7.2 33.2 1.6 8.3 15.7 2.9 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 TMF_TATA_bd PF12325.8 KKK41005.1 - 3.5 7.9 40.9 7 6.9 5.8 4.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding FAM76 PF16046.5 KKK41005.1 - 3.9 6.7 40.7 11 5.3 14.9 3.0 1 1 2 3 3 3 0 FAM76 protein Exonuc_VII_L PF02601.15 KKK41005.1 - 4 6.9 27.4 6.5 6.2 14.5 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DASH_Dam1 PF08653.10 KKK41005.1 - 4.1 7.3 12.5 6.6 6.6 0.6 4.8 4 1 0 4 4 4 0 DASH complex subunit Dam1 PspA_IM30 PF04012.12 KKK41005.1 - 4.2 6.9 32.3 15 5.1 4.1 3.5 1 1 2 3 3 3 0 PspA/IM30 family KASH_CCD PF14662.6 KKK41005.1 - 4.3 7.1 43.5 76 3.1 41.3 2.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF2935 PF11155.8 KKK41005.1 - 5.1 7.5 11.0 8.3 6.8 1.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) Jnk-SapK_ap_N PF09744.9 KKK41005.1 - 5.5 7.2 43.9 4.9 7.3 12.3 3.5 1 1 2 3 3 2 0 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 KKK41005.1 - 6 7.1 36.6 12 6.2 2.6 4.9 1 1 4 5 5 5 0 JNK-interacting protein leucine zipper II BLOC1_2 PF10046.9 KKK41005.1 - 6.5 7.1 33.8 27 5.2 16.0 4.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OEP PF02321.18 KKK41005.1 - 7.1 6.4 22.9 0.14 11.9 9.2 2.9 1 1 1 3 3 3 0 Outer membrane efflux protein HOOK PF05622.12 KKK41005.1 - 7.4 4.6 42.3 31 2.5 42.3 2.0 1 1 0 1 1 1 0 HOOK protein Prp19 PF08606.11 KKK41005.1 - 7.5 6.6 9.5 1.1 9.3 0.1 3.9 3 1 1 4 4 2 0 Prp19/Pso4-like N6_N4_Mtase PF01555.18 KKK41006.1 - 6.4e-46 156.9 4.8 1.2e-45 156.0 4.8 1.5 1 0 0 1 1 1 1 DNA methylase MethyltransfD12 PF02086.15 KKK41006.1 - 4.9e-06 26.4 6.3 0.00021 21.1 0.1 2.4 2 0 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 KKK41006.1 - 0.009 16.7 0.0 0.02 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fucose_iso_C PF02952.17 KKK41007.1 - 3.1e-26 91.8 0.0 5.8e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 L-fucose isomerase, C-terminal domain ATP-synt_ab_Xtn PF16886.5 KKK41007.1 - 0.085 12.7 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension GT87 PF09594.10 KKK41008.1 - 4e-14 52.9 5.2 6.2e-14 52.3 5.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 87 GT87 PF09594.10 KKK41010.1 - 8.5e-14 51.8 3.6 8.5e-14 51.8 3.6 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 87 DUF5400 PF17379.2 KKK41010.1 - 0.0042 17.5 0.3 0.0042 17.5 0.3 3.9 2 2 1 4 4 4 1 Family of unknown function (DUF5400) PMT_2 PF13231.6 KKK41010.1 - 0.0068 16.6 12.8 0.0068 16.6 12.8 3.6 3 1 1 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase TMEM154 PF15102.6 KKK41010.1 - 0.66 9.9 4.4 1.9 8.4 0.7 2.6 2 0 0 2 2 2 0 TMEM154 protein family His_biosynth PF00977.21 KKK41011.1 - 1.2e-64 217.9 0.8 1.4e-64 217.7 0.8 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 KKK41011.1 - 3.1e-06 26.8 4.1 0.00078 19.0 0.1 2.2 1 1 0 2 2 2 2 PcrB family FMN_dh PF01070.18 KKK41011.1 - 0.00026 20.1 0.4 0.12 11.4 0.1 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase CutC PF03932.14 KKK41011.1 - 0.00042 19.9 0.8 0.18 11.3 0.0 3.1 1 1 1 3 3 3 1 CutC family IMPDH PF00478.25 KKK41011.1 - 0.0012 17.9 0.2 0.26 10.2 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Ribul_P_3_epim PF00834.19 KKK41011.1 - 0.0017 17.8 0.3 0.88 8.9 0.1 2.2 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family IGPS PF00218.21 KKK41011.1 - 0.004 16.4 0.2 0.028 13.6 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.17 KKK41011.1 - 0.0064 15.6 0.3 0.25 10.4 0.1 2.1 1 1 0 2 2 2 1 Dihydrouridine synthase (Dus) NanE PF04131.14 KKK41011.1 - 0.0088 15.3 0.1 0.93 8.6 0.0 2.1 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KKK41011.1 - 0.019 14.3 0.9 0.48 9.7 0.1 2.1 1 1 1 2 2 2 0 Thiamine monophosphate synthase ThiG PF05690.14 KKK41011.1 - 0.062 12.6 0.4 5.3 6.3 0.0 2.4 1 1 2 3 3 3 0 Thiazole biosynthesis protein ThiG DsbD_2 PF13386.6 KKK41012.1 - 4.5e-11 43.1 12.3 9.7e-08 32.2 6.0 2.1 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DUF3087 PF11286.8 KKK41012.1 - 0.01 15.3 0.5 0.01 15.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) PCI PF01399.27 KKK41013.1 - 4e-21 75.5 9.0 4.2e-05 24.0 0.0 5.5 2 1 3 5 5 5 4 PCI domain DDRGK PF09756.9 KKK41013.1 - 4.5e-15 55.7 18.9 1.7e-05 24.5 2.7 4.8 3 2 2 5 5 5 4 DDRGK domain E3_UFM1_ligase PF09743.9 KKK41013.1 - 6.9e-15 55.4 11.5 7.4e-14 52.0 5.7 2.7 1 1 0 2 2 2 2 E3 UFM1-protein ligase 1 FeoC PF09012.10 KKK41013.1 - 2e-06 27.8 0.2 1.1 9.4 0.1 4.0 3 0 0 3 3 3 2 FeoC like transcriptional regulator Ribosomal_S25 PF03297.15 KKK41013.1 - 8.2e-06 26.0 10.9 0.00028 21.0 0.4 4.7 1 1 4 5 5 5 1 S25 ribosomal protein DUF977 PF06163.11 KKK41013.1 - 0.00081 19.3 0.4 0.13 12.2 0.1 2.9 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF977) HTH_DeoR PF08220.12 KKK41013.1 - 0.0026 17.5 0.2 11 5.9 0.0 4.0 4 0 0 4 4 4 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KKK41013.1 - 0.0042 17.4 1.0 8 6.9 0.0 4.1 4 0 0 4 4 4 1 Transcriptional regulator HTH_24 PF13412.6 KKK41013.1 - 0.0061 16.1 0.1 0.82 9.3 0.0 2.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 KKK41013.1 - 0.03 14.3 0.9 10 6.1 0.0 3.5 3 0 0 3 3 3 0 HTH domain HTH_10 PF04967.12 KKK41013.1 - 0.067 13.0 0.1 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain HTH_9 PF08221.11 KKK41013.1 - 0.54 10.4 3.6 11 6.2 0.0 4.2 5 0 0 5 5 5 0 RNA polymerase III subunit RPC82 helix-turn-helix domain zf_Rg PF17915.1 KKK41013.1 - 0.88 9.0 3.7 20 4.7 0.1 2.6 2 0 0 2 2 2 0 Reverse gyrase zinc finger Sigma70_r1_1 PF03979.14 KKK41013.1 - 1.1 9.3 4.7 2.6 8.1 0.1 3.6 4 0 0 4 4 4 0 Sigma-70 factor, region 1.1 zf-AN1 PF01428.16 KKK41013.1 - 1.9 8.7 19.4 0.029 14.5 11.4 2.1 2 0 0 2 2 1 0 AN1-like Zinc finger Pyr_redox_2 PF07992.14 KKK41015.1 - 2.4e-20 73.0 0.0 2.7e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK41015.1 - 3.5e-18 65.9 0.8 3.1e-14 53.0 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK41015.1 - 4.2e-09 36.8 1.8 0.00041 20.9 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK41015.1 - 0.00071 19.0 0.0 0.006 16.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK41015.1 - 0.0011 17.8 1.9 0.36 9.5 0.6 2.4 3 0 0 3 3 3 2 HI0933-like protein AAA_14 PF13173.6 KKK41015.1 - 0.038 14.0 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain GIDA PF01134.22 KKK41015.1 - 0.09 11.8 1.3 0.36 9.9 0.9 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A Glycos_transf_2 PF00535.26 KKK41016.1 - 1.7e-22 80.0 0.0 2.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 KKK41016.1 - 0.0001 22.8 0.0 0.00019 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KKK41016.1 - 0.0025 17.7 0.0 0.0037 17.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KKK41016.1 - 0.004 16.7 0.1 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 PIG-L PF02585.17 KKK41017.1 - 6.2e-22 78.6 0.0 1.2e-21 77.7 0.0 1.5 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase AI-2E_transport PF01594.16 KKK41018.1 - 0.81 8.8 3.7 2 7.5 0.1 2.2 2 0 0 2 2 2 0 AI-2E family transporter Syntaxin_2 PF14523.6 KKK41018.1 - 2 8.8 4.8 5.9 7.3 1.1 2.8 3 0 0 3 3 3 0 Syntaxin-like protein Amidohydro_2 PF04909.14 KKK41019.1 - 1.1e-24 87.7 0.0 1.5e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase PIF PF05092.12 KKK41019.1 - 0.076 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity URO-D PF01208.17 KKK41020.1 - 9.7e-23 80.9 0.0 1.8e-22 80.0 0.0 1.4 1 1 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Spt20 PF12090.8 KKK41020.1 - 0.071 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Spt20 family DinB_2 PF12867.7 KKK41021.1 - 5.8e-06 26.8 0.0 9e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 DinB superfamily Hfx_Cass5 PF18287.1 KKK41021.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 DinB_2 PF12867.7 KKK41022.1 - 5.9e-10 39.8 0.0 6.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 DinB superfamily Thioredoxin_3 PF13192.6 KKK41023.1 - 1.2e-16 60.5 1.4 1.8e-10 40.7 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin PF00085.20 KKK41023.1 - 4.3e-09 36.3 0.1 0.0001 22.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KKK41023.1 - 1.7e-08 34.8 1.0 0.0022 18.4 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KKK41023.1 - 7.8e-07 28.9 0.5 6.2e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin Glutaredoxin PF00462.24 KKK41023.1 - 3e-05 24.1 0.3 0.1 12.9 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin DUF836 PF05768.14 KKK41023.1 - 7.6e-05 23.0 0.0 0.4 11.1 0.1 2.2 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Redoxin PF08534.10 KKK41023.1 - 0.0012 18.6 0.0 0.91 9.2 0.0 2.2 2 0 0 2 2 2 2 Redoxin ABC_transp_aux PF09822.9 KKK41023.1 - 0.005 16.3 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 1 ABC-type uncharacterized transport system Thioredoxin_8 PF13905.6 KKK41023.1 - 0.084 13.2 0.3 7.2 7.0 0.0 3.1 2 2 2 4 4 4 0 Thioredoxin-like TrbC_Ftype PF09673.10 KKK41023.1 - 0.15 12.1 0.0 0.75 9.9 0.0 2.0 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_3 PF13192.6 KKK41024.1 - 4.2e-20 71.6 0.5 1.8e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin PF00085.20 KKK41024.1 - 8.4e-13 48.2 0.1 3.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 KKK41024.1 - 3.2e-08 33.7 0.2 3.8e-05 23.8 0.1 2.4 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin_2 PF13098.6 KKK41024.1 - 6.2e-08 33.1 1.5 0.0069 16.8 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KKK41024.1 - 3.7e-07 30.0 0.3 0.0031 17.3 0.1 2.5 2 1 0 2 2 2 2 Thioredoxin DUF836 PF05768.14 KKK41024.1 - 3.7e-06 27.3 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) ABC_transp_aux PF09822.9 KKK41024.1 - 6.9e-05 22.4 0.3 0.0057 16.2 0.3 2.1 1 1 1 2 2 2 1 ABC-type uncharacterized transport system TraF PF13728.6 KKK41024.1 - 0.00019 21.3 0.0 0.24 11.2 0.0 2.4 2 1 0 2 2 2 2 F plasmid transfer operon protein TrbC_Ftype PF09673.10 KKK41024.1 - 0.0045 17.0 0.2 0.42 10.7 0.0 2.7 2 2 0 2 2 2 1 Type-F conjugative transfer system pilin assembly protein Thioredoxin_8 PF13905.6 KKK41024.1 - 0.0052 17.1 1.0 0.1 13.0 0.2 2.8 2 2 0 2 2 2 1 Thioredoxin-like DSBA PF01323.20 KKK41024.1 - 0.0068 16.2 0.2 0.33 10.7 0.0 2.5 2 1 1 3 3 3 1 DSBA-like thioredoxin domain HyaE PF07449.11 KKK41024.1 - 0.066 13.2 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF1525 PF07511.11 KKK41024.1 - 0.16 12.1 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) PAS_8 PF13188.7 KKK41025.1 - 2.7e-05 24.1 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain GAF PF01590.26 KKK41025.1 - 5.5e-05 23.8 0.0 0.00012 22.7 0.0 1.6 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 KKK41025.1 - 0.0009 19.6 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS_7 PF12860.7 KKK41025.1 - 0.00092 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KKK41025.1 - 0.0094 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold MMR_HSR1 PF01926.23 KKK41028.1 - 1.9e-09 37.6 0.2 4.4e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KKK41028.1 - 2.9e-08 33.6 0.1 7.2e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1_Xtn PF16897.5 KKK41028.1 - 4.7e-08 33.0 2.5 5.1e-08 32.9 0.4 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KKK41028.1 - 0.016 14.7 0.0 0.04 13.5 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B GPAT_N PF14829.6 KKK41028.1 - 0.021 14.8 0.0 1.7 8.7 0.0 2.9 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal ATPase PF06745.13 KKK41028.1 - 0.047 13.0 2.2 0.081 12.3 0.4 2.1 2 0 0 2 2 2 0 KaiC cobW PF02492.19 KKK41028.1 - 0.047 13.3 0.4 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KKK41028.1 - 0.27 11.1 5.3 0.69 9.8 1.2 2.9 2 2 1 3 3 3 0 RsgA GTPase Peptidase_C50 PF03568.17 KKK41028.1 - 0.36 9.9 3.7 1.9 7.5 0.0 3.0 3 1 1 4 4 4 0 Peptidase family C50 DEAD PF00270.29 KKK41029.1 - 1.3e-18 67.4 0.2 2.9e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK41029.1 - 3.5e-17 62.7 0.2 2e-16 60.3 0.2 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DnaJ_CXXCXGXG PF00684.19 KKK41031.1 - 7e-09 35.9 31.6 8.5e-07 29.2 16.4 2.4 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 KKK41031.1 - 0.14 12.2 14.0 3.8 7.5 0.6 3.5 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KKK41031.1 - 0.22 11.5 9.1 1.3 9.1 1.2 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF3716 PF12511.8 KKK41031.1 - 2.4 8.3 11.1 7.1 6.8 8.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) Stc1 PF12898.7 KKK41031.1 - 4.4 7.9 16.4 0.47 11.0 3.5 2.7 2 1 1 3 3 3 0 Stc1 domain HypA PF01155.19 KKK41031.1 - 8.1 6.5 11.7 8.8 6.4 0.9 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Succ_CoA_lig PF13607.6 KKK41037.1 - 1.6e-34 118.6 0.0 4.2e-34 117.3 0.0 1.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK41037.1 - 2.2e-08 34.6 0.0 3.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK41037.1 - 0.00038 21.1 0.0 0.0011 19.7 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Pterin_bind PF00809.22 KKK41038.1 - 4.3e-45 154.3 0.0 5e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HATPase_c PF02518.26 KKK41039.1 - 1.6e-22 80.1 0.0 1.8e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKK41039.1 - 0.00035 20.4 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase COesterase PF00135.28 KKK41042.1 - 5.1e-21 75.1 0.0 5.6e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family PRD PF00874.20 KKK41042.1 - 0.042 14.1 1.2 0.085 13.2 0.6 1.8 1 1 1 2 2 2 0 PRD domain Fapy_DNA_glyco PF01149.24 KKK41043.1 - 6.9e-06 26.7 0.2 1.5e-05 25.6 0.2 1.9 1 1 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FAM92 PF06730.11 KKK41044.1 - 7.5e-06 25.5 15.8 2.2e-05 24.0 15.8 1.6 1 1 0 1 1 1 1 FAM92 protein DUF4398 PF14346.6 KKK41044.1 - 0.0021 18.6 4.7 0.0021 18.6 4.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4398) ALMT PF11744.8 KKK41044.1 - 0.53 9.0 18.2 0.68 8.7 18.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-PHD-like PF15446.6 KKK41044.1 - 0.56 9.8 3.6 0.98 9.0 3.4 1.6 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Spo12 PF05032.12 KKK41044.1 - 1.9 8.5 5.1 0.34 10.9 1.1 1.9 2 0 0 2 2 2 0 Spo12 family MFS_1 PF07690.16 KKK41045.1 - 1.7e-16 60.1 47.3 3.3e-09 36.2 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 KKK41045.1 - 0.00023 19.6 3.6 0.00042 18.7 1.3 2.0 2 0 0 2 2 2 1 BT1 family MFS_1_like PF12832.7 KKK41045.1 - 0.00035 19.5 30.0 0.0024 16.8 8.7 2.3 1 1 0 2 2 2 2 MFS_1 like family EI24 PF07264.11 KKK41045.1 - 0.01 16.1 13.6 0.01 16.1 13.6 3.3 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) ETRAMP PF09716.10 KKK41045.1 - 0.49 10.5 3.5 1.1 9.4 0.1 3.2 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF2738 PF10927.8 KKK41046.1 - 0.089 11.9 0.0 0.095 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) VAPB_antitox PF02697.14 KKK41047.1 - 4.8e-15 56.1 1.3 5.3e-15 55.9 1.3 1.2 1 0 0 1 1 1 1 Putative antitoxin CDV3 PF15359.6 KKK41047.1 - 0.12 12.9 0.3 0.14 12.7 0.3 1.1 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 RHH_1 PF01402.21 KKK41048.1 - 5.5e-05 22.9 1.5 8.9e-05 22.3 1.5 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_3 PF12651.7 KKK41048.1 - 0.0074 16.2 0.9 0.013 15.4 0.9 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix domain UPF0175 PF03683.13 KKK41048.1 - 0.016 14.9 0.4 0.023 14.4 0.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0175) SGL PF08450.12 KKK41049.1 - 1.4e-45 155.9 0.0 1.5e-45 155.7 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KKK41049.1 - 3.2e-09 36.8 0.0 3.2e-05 23.9 0.0 3.4 2 1 1 3 3 3 2 Strictosidine synthase DUF4915 PF16261.5 KKK41049.1 - 0.00017 20.9 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4915) Reg_prop PF07494.11 KKK41049.1 - 0.16 12.3 1.6 26 5.5 0.0 4.0 4 1 0 4 4 4 0 Two component regulator propeller PhoU_div PF01865.16 KKK41052.1 - 7e-09 35.3 9.6 8.4e-09 35.1 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF47 Alba PF01918.21 KKK41052.1 - 0.001 18.8 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 Alba DUF4047 PF13256.6 KKK41052.1 - 0.083 13.1 1.0 0.098 12.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) ATP-synt_C PF00137.21 KKK41053.1 - 9.4e-07 29.1 4.2 9.4e-07 29.1 4.2 2.1 2 0 0 2 2 2 1 ATP synthase subunit C 2TM PF13239.6 KKK41053.1 - 0.54 10.6 2.2 0.67 10.3 2.1 1.5 1 1 0 1 1 1 0 2TM domain Peptidase_M42 PF05343.14 KKK41057.1 - 1.5e-90 303.2 0.0 1.7e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KKK41057.1 - 1.8e-07 31.1 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KKK41057.1 - 1.9e-05 24.4 0.0 0.0025 17.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 OCRE PF17780.1 KKK41058.1 - 0.13 12.3 0.0 0.13 12.3 0.0 3.1 4 0 0 4 4 4 0 OCRE domain MFS_2 PF13347.6 KKK41059.1 - 1.8e-28 99.3 28.5 3.4e-28 98.4 28.5 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein WSS_VP PF12175.8 KKK41059.1 - 0.93 8.9 4.0 0.34 10.4 0.1 2.0 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP DUF5099 PF17025.5 KKK41060.1 - 0.58 10.6 5.7 1.8 9.0 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5099) AAA PF00004.29 KKK41061.1 - 1.2e-40 138.9 0.3 4.3e-40 137.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK41061.1 - 2.1e-14 53.0 0.1 2.5e-13 49.6 0.0 2.6 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 KKK41061.1 - 5.4e-06 26.6 0.0 2e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK41061.1 - 1.3e-05 25.0 0.0 4.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK41061.1 - 1.6e-05 24.9 0.1 6.5e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 KKK41061.1 - 2.9e-05 23.9 0.0 8.6e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KKK41061.1 - 0.00044 20.7 0.1 0.006 17.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KKK41061.1 - 0.00047 20.5 0.1 0.021 15.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK41061.1 - 0.0011 19.5 0.0 0.0062 17.1 0.0 2.2 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KKK41061.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KKK41061.1 - 0.0023 17.2 0.1 0.0059 15.9 0.1 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 KKK41061.1 - 0.0065 15.7 0.0 0.032 13.4 0.0 2.2 1 1 2 3 3 3 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KKK41061.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 KKK41061.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KKK41061.1 - 0.02 15.0 0.0 0.15 12.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 KKK41061.1 - 0.022 14.1 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK41061.1 - 0.027 14.6 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KKK41061.1 - 0.031 14.7 0.0 0.074 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK41061.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK41061.1 - 0.062 12.8 0.0 0.19 11.2 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 KKK41061.1 - 0.074 12.8 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KKK41061.1 - 0.097 12.4 0.2 0.29 10.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK41061.1 - 0.099 12.4 0.1 0.27 10.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KKK41061.1 - 0.11 11.8 0.9 0.31 10.3 0.0 2.1 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 KKK41061.1 - 0.11 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KKK41061.1 - 0.12 11.9 0.1 0.41 10.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KKK41061.1 - 0.13 12.4 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Arf PF00025.21 KKK41062.1 - 1.5e-07 31.1 2.8 6.2e-07 29.0 2.8 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK41062.1 - 0.00048 19.8 0.3 0.0026 17.4 0.2 2.1 2 0 0 2 2 2 1 Ras family G-alpha PF00503.20 KKK41062.1 - 0.0026 17.0 6.3 0.0054 15.9 5.4 1.9 1 1 1 2 2 2 1 G-protein alpha subunit DrrA_P4M PF14860.6 KKK41062.1 - 0.078 12.8 4.6 3.2 7.7 1.7 3.3 2 1 1 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain Barstar PF01337.18 KKK41062.1 - 0.12 12.4 0.0 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Barstar (barnase inhibitor) DUF4199 PF13858.6 KKK41063.1 - 0.23 11.8 20.6 0.56 10.6 20.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) DHHC PF01529.20 KKK41063.1 - 0.41 10.8 14.0 0.02 15.0 6.9 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase FeoB_associated PF12669.7 KKK41063.1 - 0.6 10.5 0.2 0.6 10.5 0.2 2.6 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Anoctamin PF04547.12 KKK41063.1 - 1.4 7.7 8.4 2 7.2 8.0 1.5 1 1 0 1 1 1 0 Calcium-activated chloride channel PsbW PF07123.12 KKK41063.1 - 2.4 8.2 6.8 0.082 12.9 1.0 1.5 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) DUF2730 PF10805.8 KKK41063.1 - 4.9 7.3 4.5 13 5.9 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF3810 PF12725.7 KKK41063.1 - 5.1 6.4 11.9 6 6.1 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Cyclophil_like PF04126.13 KKK41066.1 - 1.1e-32 112.4 0.0 1.3e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 KKK41066.1 - 2.6e-07 30.6 0.0 4.4e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin-like family DUF3830 PF12903.7 KKK41066.1 - 1.7e-06 27.7 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) RHH_1 PF01402.21 KKK41067.1 - 2.7e-05 23.9 0.2 3.2e-05 23.7 0.2 1.0 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_5 PF07878.11 KKK41067.1 - 0.0049 16.7 0.1 0.0069 16.2 0.1 1.6 1 1 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicB_lk_antitox PF15919.5 KKK41067.1 - 0.044 13.9 0.0 0.044 13.9 0.0 1.0 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system EcKinase PF02958.20 KKK41068.1 - 9.6e-18 64.5 0.2 1.6e-17 63.8 0.2 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 KKK41068.1 - 2.9e-10 39.6 0.3 3.6e-10 39.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 KKK41068.1 - 1.9e-09 37.8 0.0 3.5e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KKK41068.1 - 0.00044 19.9 1.5 0.0012 18.5 1.5 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Acetyltransf_10 PF13673.7 KKK41069.1 - 0.00067 19.6 0.0 0.00068 19.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK41069.1 - 0.0033 17.8 0.0 0.0034 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK41069.1 - 0.026 14.7 0.0 0.027 14.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Bac_luciferase PF00296.20 KKK41071.1 - 8.7e-44 150.2 0.0 1.9e-43 149.1 0.0 1.4 2 0 0 2 2 2 1 Luciferase-like monooxygenase Hexapep PF00132.24 KKK41072.1 - 6.3e-10 38.4 10.8 7e-08 31.9 2.4 3.1 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK41072.1 - 0.0079 15.9 16.6 3 7.7 13.5 4.3 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KKK41072.1 - 0.42 8.7 4.0 0.43 8.7 3.6 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) cobW PF02492.19 KKK41073.1 - 2.8e-23 82.4 1.0 2.8e-23 82.4 1.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KKK41073.1 - 3.6e-05 22.9 0.8 0.00042 19.4 0.8 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KKK41073.1 - 4.9e-05 22.9 3.0 0.0008 19.0 3.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK41073.1 - 0.00026 20.9 0.5 0.18 11.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase SRP54 PF00448.22 KKK41073.1 - 0.002 17.8 0.2 0.002 17.8 0.2 1.8 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.15 KKK41073.1 - 0.0028 17.7 0.1 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KKK41073.1 - 0.0063 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin TsaE PF02367.17 KKK41073.1 - 0.014 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KKK41073.1 - 0.017 14.9 0.1 0.04 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKK41073.1 - 0.03 14.6 0.0 0.067 13.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain MobB PF03205.14 KKK41073.1 - 0.033 14.1 0.1 0.079 12.9 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1_Xtn PF16897.5 KKK41073.1 - 0.034 14.2 0.6 0.034 14.2 0.6 2.5 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain ATP-synt_ab PF00006.25 KKK41073.1 - 0.034 13.8 0.9 0.075 12.7 0.2 1.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 KKK41073.1 - 0.036 14.4 0.0 0.049 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KKK41073.1 - 0.041 13.7 0.4 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KKK41073.1 - 0.043 13.4 3.7 0.37 10.4 0.1 2.8 2 1 1 3 3 3 0 Ras family NB-ARC PF00931.22 KKK41073.1 - 0.045 12.9 0.3 0.13 11.4 0.3 1.7 1 1 0 1 1 1 0 NB-ARC domain Roc PF08477.13 KKK41073.1 - 0.054 13.7 0.1 0.38 11.0 0.1 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KKK41073.1 - 0.065 12.8 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 KKK41073.1 - 0.096 13.0 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IMPDH PF00478.25 KKK41073.1 - 1 8.3 8.6 0.26 10.2 4.1 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain 3HCDH_N PF02737.18 KKK41074.1 - 1.3e-34 119.7 0.0 3.1e-34 118.4 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK41074.1 - 1.5e-16 60.8 0.0 3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK41074.1 - 1.1e-06 28.9 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_4 PF02056.16 KKK41074.1 - 2e-05 24.2 0.1 3.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase AlaDh_PNT_C PF01262.21 KKK41074.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3Beta_HSD PF01073.19 KKK41074.1 - 0.0025 16.9 0.1 0.0049 15.9 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_Gly3P_dh_N PF01210.23 KKK41074.1 - 0.0046 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 KKK41074.1 - 0.024 14.2 0.2 0.041 13.4 0.2 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 KKK41074.1 - 0.045 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 KKK41074.1 - 0.099 12.0 0.1 0.33 10.3 0.1 1.8 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KKK41074.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain SL4P PF17618.2 KKK41074.1 - 0.12 12.5 1.4 0.24 11.5 1.4 1.5 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein DUF1931 PF09123.11 KKK41074.1 - 0.12 12.5 1.1 0.2 11.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Helicase_C PF00271.31 KKK41075.1 - 0.052 13.9 0.8 2.5 8.5 0.1 2.6 3 0 0 3 3 3 0 Helicase conserved C-terminal domain Fe-ADH PF00465.19 KKK41076.1 - 7.3e-85 284.9 0.0 8.8e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK41076.1 - 2.6e-16 60.1 0.1 4.5e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase AFOR_C PF01314.18 KKK41077.1 - 2.5e-91 306.5 0.0 3.3e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK41077.1 - 6e-70 235.2 0.0 6.6e-69 231.7 0.0 2.0 2 0 0 2 2 2 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain DUF2672 PF10878.8 KKK41077.1 - 0.09 12.7 0.7 0.6 10.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) Fer4_16 PF13484.6 KKK41078.1 - 3.8e-13 50.2 7.6 7.4e-13 49.2 7.6 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain HEAT_2 PF13646.6 KKK41078.1 - 2.9e-07 30.8 0.0 5.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 HEAT repeats Fer4 PF00037.27 KKK41078.1 - 0.0053 16.5 8.8 0.67 9.9 1.7 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK41078.1 - 0.0061 17.1 6.6 0.023 15.3 6.6 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41078.1 - 0.12 12.4 10.4 0.41 10.8 1.3 2.7 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK41078.1 - 0.28 12.2 11.6 0.87 10.7 1.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK41078.1 - 1.3 9.7 9.8 8.1 7.2 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 KKK41078.1 - 2.6 8.3 11.0 2.5 8.3 1.4 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41078.1 - 4.4 7.5 11.1 0.9 9.7 0.8 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain zinc_ribbon_15 PF17032.5 KKK41079.1 - 1.3e-09 38.7 14.7 0.0095 16.7 1.2 3.5 3 0 0 3 3 3 3 zinc-ribbon family DZR PF12773.7 KKK41079.1 - 2.4e-09 37.1 13.4 0.00065 19.7 0.9 3.3 3 0 0 3 3 3 3 Double zinc ribbon UPF0547 PF10571.9 KKK41079.1 - 4.6e-07 29.8 1.6 4.6e-07 29.8 1.6 3.1 4 0 0 4 4 4 1 Uncharacterised protein family UPF0547 HTH_23 PF13384.6 KKK41079.1 - 0.00021 21.0 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain zf-ribbon_3 PF13248.6 KKK41079.1 - 0.00026 20.3 2.1 0.00026 20.3 2.1 3.6 3 1 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK41079.1 - 0.00063 19.4 4.2 0.00063 19.4 4.2 4.0 3 1 0 3 3 3 2 zinc-ribbon domain HypA PF01155.19 KKK41079.1 - 0.0088 16.1 9.5 1.5 8.8 0.2 3.4 3 0 0 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sigma70_r4_2 PF08281.12 KKK41079.1 - 0.032 13.9 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 zf-DBF PF07535.12 KKK41079.1 - 0.038 14.1 0.3 0.038 14.1 0.3 2.8 2 0 0 2 2 2 0 DBF zinc finger GerE PF00196.19 KKK41079.1 - 0.039 13.5 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_Tnp_1 PF01527.20 KKK41079.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Transposase zinc_ribbon_5 PF13719.6 KKK41079.1 - 0.23 11.3 3.9 1.1 9.0 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain GFA PF04828.14 KKK41079.1 - 0.44 10.9 14.5 6.9 7.1 2.0 4.5 3 2 1 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.12 KKK41079.1 - 2.5 7.7 13.2 6.6 6.3 2.4 4.3 4 0 0 4 4 4 0 TFIIB zinc-binding zinc-ribbon_6 PF10005.9 KKK41079.1 - 2.7 8.7 9.8 14 6.5 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KKK41079.1 - 7.2 6.5 20.8 2.9 7.7 0.1 4.7 4 1 0 4 4 4 0 A2L zinc ribbon domain TackOD1 PF18551.1 KKK41079.1 - 9.3 5.9 14.6 0.25 11.0 1.3 3.1 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 HTH_Tnp_IS630 PF01710.16 KKK41079.1 - 9.8 6.3 8.9 10 6.2 0.0 3.8 4 1 0 4 4 4 0 Transposase NAD_kinase PF01513.21 KKK41080.1 - 6.9e-44 150.2 0.0 7.9e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KKK41080.1 - 2e-05 24.2 0.1 0.00012 21.7 0.0 2.3 3 0 0 3 3 3 1 Diacylglycerol kinase catalytic domain DeoRC PF00455.22 KKK41080.1 - 0.025 14.5 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 DeoR C terminal sensor domain DUF4652 PF15525.6 KKK41080.1 - 0.079 12.7 0.2 0.16 11.7 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4652) PFK PF00365.20 KKK41080.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase Peptidase_M20 PF01546.28 KKK41081.1 - 1.8e-30 106.2 0.0 2.3e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK41081.1 - 1.6e-15 56.9 0.0 3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Polo_box_3 PF18544.1 KKK41081.1 - 0.03 14.9 0.1 3.9 8.2 0.0 3.1 3 0 0 3 3 3 0 Polo box domain MMR_HSR1_Xtn PF16897.5 KKK41082.1 - 2.6e-22 78.9 0.0 6.9e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KKK41082.1 - 3e-18 66.0 0.0 6.6e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KKK41082.1 - 7.7e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KKK41082.1 - 1.5e-09 37.6 0.1 4.4e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK41082.1 - 1e-05 25.5 0.5 0.034 14.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KKK41082.1 - 0.0003 20.9 0.2 1.5 8.9 0.1 3.0 2 1 0 3 3 3 2 Dynamin family SRPRB PF09439.10 KKK41082.1 - 0.0008 18.9 1.0 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynactin_p22 PF07426.11 KKK41082.1 - 0.013 15.4 3.5 0.02 14.7 1.0 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 Baculo_11_kDa PF06143.11 KKK41082.1 - 0.028 14.0 0.0 0.073 12.6 0.0 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Rrf2 PF02082.20 KKK41082.1 - 0.13 12.6 0.2 1.6 9.1 0.3 2.3 2 0 0 2 2 2 0 Transcriptional regulator ABC_tran_CTD PF16326.5 KKK41082.1 - 0.14 12.4 0.8 0.38 11.0 0.8 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain TolA_bind_tri PF16331.5 KKK41082.1 - 0.18 11.9 0.5 0.4 10.8 0.5 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Dsl1_C PF11989.8 KKK41082.1 - 0.25 11.1 3.1 2.5 7.8 0.6 2.2 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 C terminal CorA PF01544.18 KKK41082.1 - 0.34 10.2 3.6 0.31 10.3 0.8 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 KKK41083.1 - 0.0026 17.2 13.6 0.0065 15.9 13.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF5082 PF16888.5 KKK41083.1 - 0.0046 17.2 13.3 0.0046 17.2 13.3 3.9 2 1 1 3 3 3 1 Domain of unknown function (DUF5082) FolB PF02152.18 KKK41083.1 - 0.062 13.9 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 Dihydroneopterin aldolase RasGAP_C PF03836.15 KKK41083.1 - 0.075 13.2 19.3 0.059 13.5 14.2 3.0 2 1 1 3 3 3 0 RasGAP C-terminus Nkap_C PF06047.11 KKK41083.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.2 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain FlaC_arch PF05377.11 KKK41083.1 - 0.62 10.5 8.6 7.5 7.0 0.1 4.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) LPP PF04728.13 KKK41083.1 - 0.66 10.4 6.5 18 5.8 0.2 3.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Nas2_N PF18265.1 KKK41083.1 - 0.99 9.4 5.8 9.9 6.2 0.2 3.1 2 1 0 2 2 2 0 Nas2 N_terminal domain Baculo_PEP_C PF04513.12 KKK41083.1 - 4.5 7.3 17.1 0.1 12.6 1.7 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YojJ PF10372.9 KKK41083.1 - 4.7 7.4 17.4 2.2 8.4 0.3 4.4 2 1 2 4 4 4 0 Bacterial membrane-spanning protein N-terminus Spectrin PF00435.21 KKK41083.1 - 8.4 6.9 24.0 0.55 10.7 4.8 4.1 2 1 2 4 4 4 0 Spectrin repeat Aminotran_3 PF00202.21 KKK41085.1 - 8.7e-21 74.0 0.0 9.9e-21 73.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III cIII PF08134.11 KKK41085.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 cIII protein family Exonuc_VII_S PF02609.16 KKK41085.1 - 0.45 10.6 1.9 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit Ras PF00071.22 KKK41091.1 - 5.6e-47 159.3 0.1 6.4e-47 159.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK41091.1 - 1.3e-28 99.6 0.0 1.8e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41091.1 - 1.3e-15 57.3 0.1 1.4e-15 57.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK41091.1 - 4.3e-06 26.3 0.0 6.5e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK41091.1 - 5.4e-05 22.6 0.1 7.8e-05 22.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK41091.1 - 5.7e-05 22.7 0.1 0.048 13.2 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KKK41091.1 - 0.0026 17.5 0.2 0.058 13.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKK41091.1 - 0.0052 16.9 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 KKK41091.1 - 0.032 14.2 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.6 KKK41091.1 - 0.036 14.4 0.0 0.059 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KKK41091.1 - 0.051 13.3 0.3 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S2 PF00318.20 KKK41091.1 - 0.054 12.7 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 AAA_22 PF13401.6 KKK41091.1 - 0.059 13.7 0.0 0.15 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KKK41091.1 - 0.062 13.2 0.3 0.18 11.7 0.3 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 KKK41091.1 - 0.082 12.8 0.2 0.18 11.7 0.1 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TniB PF05621.11 KKK41091.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF4116 PF13475.6 KKK41091.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Mito_fiss_Elm1 PF06258.11 KKK41091.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 CPT PF07931.12 KKK41091.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KKK41091.1 - 0.19 11.9 0.0 0.28 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AFOR_C PF01314.18 KKK41092.1 - 4.8e-88 295.7 0.0 7.1e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK41092.1 - 3.3e-54 183.8 1.1 6e-54 182.9 1.1 1.5 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Thioredoxin_9 PF14595.6 KKK41093.1 - 3.2e-15 56.0 0.0 1.6e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin PF00085.20 KKK41093.1 - 0.00094 19.1 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 KKK41093.1 - 0.0014 19.0 0.2 0.21 11.9 0.0 2.8 1 1 1 2 2 2 1 Thioredoxin-like DUF953 PF06110.11 KKK41093.1 - 0.0037 16.9 0.1 0.0063 16.1 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.6 KKK41093.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KKK41093.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 KKK41093.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.4 1 1 0 1 1 1 0 Redoxin PAS_9 PF13426.7 KKK41094.1 - 3.9e-51 171.6 14.0 7.6e-16 58.3 0.0 6.5 6 0 0 6 6 6 5 PAS domain PAS_3 PF08447.12 KKK41094.1 - 9e-41 138.1 5.4 1.5e-15 57.2 0.0 6.2 6 0 0 6 6 6 4 PAS fold PAS PF00989.25 KKK41094.1 - 9.8e-38 128.6 0.4 2e-13 50.3 0.0 6.4 6 0 0 6 6 6 5 PAS fold PAS_4 PF08448.10 KKK41094.1 - 9.9e-32 109.5 0.0 1.4e-08 35.0 0.0 6.6 6 2 0 6 6 6 4 PAS fold PAS_8 PF13188.7 KKK41094.1 - 2.3e-25 88.1 0.0 2.8e-11 43.1 0.0 5.4 6 0 0 6 6 5 2 PAS domain HATPase_c PF02518.26 KKK41094.1 - 4.5e-24 85.1 1.0 1e-23 83.9 0.4 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK41094.1 - 1.4e-11 44.2 0.2 3.5e-11 43.0 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 KKK41094.1 - 1e-07 32.1 6.3 1.4 9.1 0.1 7.3 6 2 0 6 6 6 1 PAS fold H_kinase_N PF12282.8 KKK41094.1 - 0.00066 19.7 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Signal transduction histidine kinase PAS_12 PF18095.1 KKK41094.1 - 0.012 15.2 2.5 3.6 7.2 0.0 4.1 4 0 0 4 4 4 0 UPF0242 C-terminal PAS-like domain HATPase_c_2 PF13581.6 KKK41094.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain 3H PF02829.14 KKK41094.1 - 0.035 14.4 3.1 25 5.2 0.2 4.2 3 0 0 3 3 3 0 3H domain HATPase_c_3 PF13589.6 KKK41094.1 - 0.066 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK41095.1 - 6e-25 87.9 0.2 8.2e-25 87.5 0.2 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK41095.1 - 0.0008 19.4 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KKK41095.1 - 0.0023 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK41095.1 - 0.0035 17.2 4.5 0.0038 17.1 0.4 2.6 1 1 1 2 2 2 1 GHKL domain DUF4139 PF13598.6 KKK41096.1 - 0.0087 15.8 0.3 0.02 14.6 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) NAD_binding_2 PF03446.15 KKK41096.1 - 0.036 14.2 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SYCP2_SLD PF18584.1 KKK41096.1 - 0.13 12.5 2.2 0.46 10.7 0.1 3.1 3 0 0 3 3 3 0 Synaptonemal complex 2 Spt16M-like domain Fib_alpha PF08702.10 KKK41096.1 - 6.6 6.9 10.0 23 5.1 10.0 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ras PF00071.22 KKK41097.1 - 4.8e-37 127.0 0.7 1.2e-24 86.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK41097.1 - 5e-25 88.0 0.1 2.3e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41097.1 - 1.5e-11 44.1 0.1 3.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK41097.1 - 8.2e-05 22.7 0.0 0.0089 16.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 KKK41097.1 - 0.00019 20.8 1.0 0.00027 20.3 0.1 1.8 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 KKK41097.1 - 0.00032 20.6 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KKK41097.1 - 0.00049 19.5 0.1 0.01 15.2 0.1 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KKK41097.1 - 0.0056 16.7 0.6 0.026 14.6 0.3 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK41097.1 - 0.0078 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region FeoB_N PF02421.18 KKK41097.1 - 0.008 15.7 0.1 0.73 9.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KKK41097.1 - 0.021 14.6 0.1 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PPL4 PF18188.1 KKK41097.1 - 0.044 13.7 0.3 0.089 12.7 0.3 1.4 1 0 0 1 1 1 0 Prim-pol 4 Dynamin_N PF00350.23 KKK41097.1 - 0.045 13.8 0.3 0.092 12.8 0.1 1.7 2 0 0 2 2 2 0 Dynamin family T2SSE PF00437.20 KKK41097.1 - 0.051 12.6 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 KKK41097.1 - 0.073 13.6 0.0 0.21 12.1 0.0 1.7 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 KKK41097.1 - 0.075 12.8 0.7 5.2 6.8 0.3 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KKK41097.1 - 0.096 11.8 0.1 0.16 11.1 0.1 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KKK41097.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 KKK41097.1 - 0.29 10.2 7.4 0.42 9.7 2.0 2.9 1 1 0 2 2 2 0 G-protein alpha subunit LOH1CR12 PF10158.9 KKK41098.1 - 0.061 13.3 0.9 1.3 9.1 0.0 2.0 1 1 1 2 2 2 0 Tumour suppressor protein DUF241 PF03087.14 KKK41098.1 - 0.12 12.2 5.5 0.14 12.0 5.5 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Prefoldin PF02996.17 KKK41098.1 - 0.31 11.0 7.4 1.5 8.7 2.1 2.0 1 1 1 2 2 2 0 Prefoldin subunit XhlA PF10779.9 KKK41098.1 - 0.69 10.2 6.8 4.2 7.7 2.2 2.1 1 1 1 2 2 2 0 Haemolysin XhlA Spc24 PF08286.11 KKK41098.1 - 4.7 7.5 8.8 2.6 8.3 2.4 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YojJ PF10372.9 KKK41098.1 - 7.2 6.8 10.3 10 6.3 2.0 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Acyl-CoA_dh_1 PF00441.24 KKK41099.1 - 1.4e-19 70.8 0.1 2.7e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK41099.1 - 7.2e-12 45.3 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK41099.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Mon1 PF03164.14 KKK41100.1 - 0.00018 20.8 2.7 0.00022 20.4 2.7 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 RPAP3_C PF13877.6 KKK41100.1 - 0.0027 18.2 0.5 0.12 12.9 0.2 2.6 2 1 0 2 2 2 1 Potential Monad-binding region of RPAP3 Spt5-NGN PF03439.13 KKK41101.1 - 1.8e-13 50.2 0.0 4.5e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CotE PF10628.9 KKK41101.1 - 0.059 13.0 0.6 0.11 12.1 0.6 1.5 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) NusG PF02357.19 KKK41101.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcription termination factor nusG DUF3945 PF13101.6 KKK41101.1 - 0.13 12.0 1.1 0.26 11.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) Glyco_hydro_65C PF03633.15 KKK41101.1 - 0.17 11.8 0.3 0.7 9.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain eIF-1a PF01176.19 KKK41102.1 - 1.2e-16 60.3 2.0 1.8e-16 59.7 2.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NiFeSe_Hases PF00374.19 KKK41105.1 - 1.8e-17 63.4 0.1 1e-05 24.6 0.0 3.0 2 1 1 3 3 3 3 Nickel-dependent hydrogenase Complex1_49kDa PF00346.19 KKK41105.1 - 0.001 18.2 0.0 0.41 9.7 0.0 2.4 2 1 0 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Fer4_16 PF13484.6 KKK41106.1 - 2.8e-10 41.0 4.3 4.7e-10 40.3 4.3 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK41106.1 - 8.4e-10 39.0 18.5 1.1e-08 35.4 7.5 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK41106.1 - 1.9e-08 34.8 4.8 3.3e-08 34.0 4.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41106.1 - 8.8e-08 32.2 5.2 1.7e-07 31.3 5.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41106.1 - 4.8e-06 26.6 9.4 0.00021 21.3 11.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41106.1 - 7.1e-06 26.5 8.2 0.00015 22.2 10.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41106.1 - 0.00028 20.9 8.4 0.038 14.1 0.7 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK41106.1 - 0.0047 17.1 3.7 0.24 11.6 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41106.1 - 0.018 14.8 14.3 0.099 12.5 2.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK41106.1 - 0.21 11.8 14.5 0.22 11.7 2.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK41106.1 - 0.68 10.6 10.8 0.36 11.4 1.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK41106.1 - 3.3 8.3 9.7 2.8 8.6 1.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_6 PF12837.7 KKK41106.1 - 3.4 7.9 14.3 0.58 10.3 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK41106.1 - 8.8 7.5 16.1 5.5 8.2 4.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK41106.1 - 9.7 7.1 11.3 16 6.4 1.5 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain CCG PF02754.16 KKK41107.1 - 2.2e-29 101.5 3.4 9.7e-17 61.0 0.8 2.2 2 0 0 2 2 2 2 Cysteine-rich domain DUF2955 PF11168.8 KKK41109.1 - 0.0014 18.4 0.4 0.0017 18.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2955) HupF_HypC PF01455.18 KKK41110.1 - 4.6e-24 84.3 0.3 5.6e-24 84.1 0.3 1.1 1 0 0 1 1 1 1 HupF/HypC family KTSC PF13619.6 KKK41110.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 KTSC domain CbiA PF01656.23 KKK41111.1 - 2.1e-18 66.6 0.1 3.2e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKK41111.1 - 3.9e-10 39.9 0.6 7.3e-10 39.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 KKK41111.1 - 3.3e-09 36.5 0.7 1.5e-05 24.6 0.2 2.6 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KKK41111.1 - 3.7e-08 33.1 0.6 0.00068 19.2 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KKK41111.1 - 1.4e-07 31.1 0.5 2.2e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 KKK41111.1 - 4e-06 26.5 0.0 0.025 14.0 0.1 2.1 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ AAA_30 PF13604.6 KKK41111.1 - 0.0045 16.7 0.0 0.0072 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK41111.1 - 0.0082 16.5 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK41111.1 - 0.018 14.8 0.1 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKK41111.1 - 0.051 14.0 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KKK41111.1 - 0.056 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Endonuclease_5 PF04493.14 KKK41112.1 - 3e-53 180.4 0.0 3.6e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V HEAT_2 PF13646.6 KKK41113.1 - 1.7e-10 41.2 0.1 3.8e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KKK41113.1 - 3.4e-08 33.1 0.0 0.028 14.7 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat TPR_MLP1_2 PF07926.12 KKK41113.1 - 0.12 12.4 26.1 0.13 12.3 4.7 4.5 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Vps51 PF08700.11 KKK41113.1 - 0.19 11.9 0.2 0.19 11.9 0.2 4.2 4 0 0 4 4 4 0 Vps51/Vps67 Spc7 PF08317.11 KKK41113.1 - 0.47 9.3 32.7 0.098 11.5 5.5 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4680 PF15730.5 KKK41113.1 - 0.83 10.0 2.4 3 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) Cadherin_2 PF08266.12 KKK41113.1 - 3.8 7.4 6.4 4.2 7.3 0.0 3.3 4 0 0 4 4 4 0 Cadherin-like MCC-bdg_PDZ PF10506.9 KKK41113.1 - 5.5 7.1 16.8 12 6.0 0.2 4.3 4 1 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome RasGAP_C PF03836.15 KKK41113.1 - 8.1 6.6 18.5 2.4 8.3 7.5 3.5 1 1 0 2 2 2 0 RasGAP C-terminus DUF4140 PF13600.6 KKK41113.1 - 9.1 6.8 12.5 12 6.5 0.5 4.0 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Pro_isomerase PF00160.21 KKK41114.1 - 1.8e-38 132.3 1.2 2.1e-38 132.1 1.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-grasp_5 PF13549.6 KKK41115.1 - 5.8e-68 228.7 0.0 8.2e-68 228.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KKK41115.1 - 1.2e-50 170.9 0.3 4.5e-50 169.0 0.1 2.1 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK41115.1 - 3.1e-22 79.2 0.0 7.7e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK41115.1 - 4.5e-15 56.1 1.8 1.5e-14 54.4 0.5 2.6 3 0 0 3 3 3 1 CoA binding domain ATP-grasp_2 PF08442.10 KKK41115.1 - 0.046 13.3 0.2 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain AAA_26 PF13500.6 KKK41116.1 - 1e-06 28.7 0.0 1.1e-06 28.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain Ac110_PIF PF07280.11 KKK41117.1 - 0.077 12.8 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Per os infectivity factor AC110 GPI-anchored PF10342.9 KKK41118.1 - 2.8e-15 56.9 26.7 5.8e-09 36.6 4.1 5.7 6 0 0 6 6 6 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_7 PF17957.1 KKK41118.1 - 3.1e-08 34.3 6.2 1.8e-05 25.4 2.4 6.6 6 0 0 6 6 6 2 Bacterial Ig domain CHB_HEX_C_1 PF13290.6 KKK41118.1 - 0.022 14.8 4.5 0.13 12.2 1.5 3.4 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain CE2_N PF17996.1 KKK41118.1 - 0.13 12.3 0.1 5 7.2 0.0 3.1 3 0 0 3 3 3 0 Carbohydrate esterase 2 N-terminal C1_2 PF03107.16 KKK41119.1 - 5.7e-05 23.3 4.3 5.7e-05 23.3 4.3 2.1 2 0 0 2 2 2 1 C1 domain zf-C3HC4_3 PF13920.6 KKK41119.1 - 8.8e-05 22.3 9.4 0.00017 21.3 9.3 1.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KKK41119.1 - 0.0039 17.2 8.3 0.025 14.6 1.1 2.2 1 1 1 2 2 2 2 Double zinc ribbon IBR PF01485.21 KKK41119.1 - 2 8.7 10.9 7.6 6.8 7.6 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-HIT PF04438.16 KKK41119.1 - 3.3 7.7 12.4 0.87 9.5 8.7 1.9 2 0 0 2 2 2 0 HIT zinc finger DUF4379 PF14311.6 KKK41120.1 - 0.5 10.8 17.0 0.043 14.2 2.0 3.4 4 0 0 4 4 4 0 Probable Zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 KKK41120.1 - 2.4 8.3 9.8 0.29 11.2 1.2 3.3 3 0 0 3 3 3 0 Transposase zinc-binding domain DRTGG PF07085.12 KKK41121.1 - 1.9e-24 85.5 0.1 3.4e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 DRTGG domain AAA_26 PF13500.6 KKK41121.1 - 4.4e-20 72.3 0.0 6.4e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KKK41121.1 - 1.7e-05 24.9 0.0 6.5e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Hpr_kinase_N PF02603.16 KKK41121.1 - 0.0023 17.9 0.0 0.0071 16.4 0.0 1.8 2 0 0 2 2 2 1 HPr Serine kinase N terminus DHHC PF01529.20 KKK41122.1 - 5.9 7.0 5.9 7.8 6.6 5.9 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DRTGG PF07085.12 KKK41123.1 - 0.00075 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 DRTGG domain DRTGG PF07085.12 KKK41124.1 - 2.2e-24 85.2 0.2 4.3e-24 84.3 0.1 1.5 2 0 0 2 2 2 1 DRTGG domain Hpr_kinase_N PF02603.16 KKK41124.1 - 0.00077 19.5 0.0 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 HPr Serine kinase N terminus CbiA PF01656.23 KKK41124.1 - 0.002 18.2 0.0 0.0054 16.8 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 KKK41124.1 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain CW_binding_2 PF04122.12 KKK41124.1 - 0.13 12.9 0.0 0.23 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 DRTGG PF07085.12 KKK41126.1 - 2.5e-09 36.9 0.0 2.9e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 DRTGG domain DUF2070 PF09843.9 KKK41127.1 - 0.27 9.5 7.8 0.28 9.4 7.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DZR PF12773.7 KKK41128.1 - 0.0009 19.2 9.1 0.0034 17.4 7.8 2.1 1 1 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 KKK41128.1 - 0.0029 17.6 7.3 0.0029 17.6 7.3 3.2 3 1 0 3 3 2 1 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 KKK41128.1 - 0.0074 16.0 10.9 0.17 11.7 0.1 3.4 3 0 0 3 3 3 2 zinc-ribbon domain DUF1610 PF07754.11 KKK41128.1 - 0.0081 16.1 7.3 0.092 12.7 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF1610) Zn-ribbon_8 PF09723.10 KKK41128.1 - 0.018 15.1 7.2 0.51 10.5 0.2 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KKK41128.1 - 0.027 13.9 4.7 0.027 13.9 4.7 2.8 2 1 0 2 2 2 0 zinc-ribbon domain DUF1272 PF06906.11 KKK41128.1 - 0.085 13.0 5.2 0.6 10.2 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_7 PF02591.15 KKK41128.1 - 0.23 11.7 0.6 0.23 11.7 0.6 2.7 3 1 0 3 3 3 0 C4-type zinc ribbon domain DUF35_N PF12172.8 KKK41128.1 - 0.26 11.2 6.2 5.8 6.9 0.2 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PhnA_Zn_Ribbon PF08274.12 KKK41128.1 - 0.27 11.2 6.8 6.3 6.8 0.2 3.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Nudix_N_2 PF14803.6 KKK41128.1 - 0.3 11.0 0.8 0.3 11.0 0.8 3.6 3 1 0 3 3 3 0 Nudix N-terminal RNA_POL_M_15KD PF02150.16 KKK41128.1 - 0.57 10.1 12.0 4.1 7.4 7.3 3.1 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit DNA_ligase_ZBD PF03119.16 KKK41128.1 - 0.84 9.7 5.7 1.7 8.8 0.5 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain GFA PF04828.14 KKK41128.1 - 1.2 9.5 9.0 16 5.9 4.2 3.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_9 PF14369.6 KKK41128.1 - 1.5 9.1 7.8 1.1 9.6 0.2 3.0 2 1 1 3 3 3 0 zinc-ribbon RecR PF02132.15 KKK41128.1 - 2 8.1 8.7 12 5.6 4.7 2.9 2 1 0 2 2 2 0 RecR protein zf-RRN7 PF11781.8 KKK41128.1 - 2 8.2 8.7 12 5.6 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 A2L_zn_ribbon PF08792.10 KKK41128.1 - 6.2 6.7 10.8 5.1 6.9 0.5 2.9 2 1 1 3 3 3 0 A2L zinc ribbon domain DZR PF12773.7 KKK41129.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 1 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK41129.1 - 0.012 15.0 4.9 0.099 12.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RRN7 PF11781.8 KKK41129.1 - 0.051 13.3 1.2 0.58 9.9 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-LITAF-like PF10601.9 KKK41129.1 - 0.07 13.4 6.0 0.37 11.1 6.0 1.9 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain HypA PF01155.19 KKK41129.1 - 0.092 12.8 0.2 0.1 12.6 0.2 1.0 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Aminotran_1_2 PF00155.21 KKK41130.1 - 5.3e-62 210.1 0.0 6.2e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK41130.1 - 5.3e-06 25.6 0.0 8.2e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Alliinase_C PF04864.13 KKK41130.1 - 1.8e-05 23.8 0.0 2.6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Allinase DegT_DnrJ_EryC1 PF01041.17 KKK41130.1 - 0.0057 16.0 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KKK41130.1 - 0.031 12.8 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK41130.1 - 0.2 10.9 0.0 0.42 9.8 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Phage_holin_3_6 PF07332.11 KKK41131.1 - 0.00011 22.2 0.9 0.00012 22.0 0.9 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III CrgA PF06781.12 KKK41131.1 - 0.00051 20.0 4.5 0.00061 19.8 4.5 1.1 1 0 0 1 1 1 1 Cell division protein CrgA DUF2207 PF09972.9 KKK41131.1 - 0.0053 15.6 3.4 0.006 15.4 3.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2244 PF10003.9 KKK41131.1 - 0.14 11.8 2.0 0.16 11.7 2.0 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Sigma_reg_N PF13800.6 KKK41131.1 - 2.4 8.5 4.9 1 9.7 0.7 1.9 1 1 1 2 2 2 0 Sigma factor regulator N-terminal FixQ PF05545.11 KKK41131.1 - 4.8 7.2 10.7 0.95 9.5 1.8 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Syndecan PF01034.20 KKK41131.1 - 5.8 6.9 9.1 5.4 7.0 1.4 2.1 1 1 1 2 2 2 0 Syndecan domain CxxCxxCC PF03692.15 KKK41133.1 - 2.7e-13 50.4 1.6 1.2e-12 48.4 1.6 2.0 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain zf-ribbon_3 PF13248.6 KKK41138.1 - 2.8e-06 26.5 1.0 4.3e-06 25.9 1.0 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK41138.1 - 1.3e-05 25.1 0.2 1.5e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK41138.1 - 0.00013 21.6 2.1 0.00021 20.9 2.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK41138.1 - 0.00015 22.4 1.4 0.00022 21.9 1.4 1.3 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 KKK41138.1 - 0.001 19.1 1.4 0.0016 18.5 1.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-4CXXC_R1 PF10497.9 KKK41138.1 - 0.042 14.1 1.2 0.085 13.1 1.2 1.5 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Cript PF10235.9 KKK41138.1 - 0.047 14.3 0.3 0.056 14.0 0.3 1.2 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT RNA_POL_M_15KD PF02150.16 KKK41138.1 - 8.2 6.4 8.1 10 6.1 0.8 2.4 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit PFL-like PF02901.15 KKK41141.1 - 3.5e-181 604.2 0.0 4.3e-181 603.8 0.0 1.0 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 KKK41141.1 - 4e-22 78.7 0.0 1.1e-21 77.4 0.0 1.8 1 0 0 1 1 1 1 Glycine radical MethyltransfD12 PF02086.15 KKK41142.1 - 1.5e-67 228.0 12.8 2.3e-67 227.5 12.8 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase AAA_5 PF07728.14 KKK41143.1 - 8.8e-18 64.6 0.0 1.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KKK41143.1 - 3.4e-13 49.6 0.0 6.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKK41143.1 - 2.9e-05 23.5 0.0 0.43 9.9 0.0 3.3 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KKK41143.1 - 0.00029 21.1 0.0 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KKK41143.1 - 0.00053 20.4 0.0 0.019 15.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KKK41143.1 - 0.0013 18.4 0.0 0.0041 16.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 KKK41143.1 - 0.025 15.1 0.0 0.063 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK41143.1 - 0.03 14.7 0.0 0.056 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KKK41143.1 - 0.046 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KKK41143.1 - 0.068 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KKK41143.1 - 0.082 12.8 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain VWA_2 PF13519.6 KKK41144.1 - 6.9e-11 42.7 2.2 1.6e-08 35.1 0.0 3.9 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KKK41144.1 - 7.5e-08 32.0 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 KKK41144.1 - 0.0035 17.3 4.1 0.0045 16.9 0.1 2.9 4 0 0 4 4 4 1 von Willebrand factor type A domain DUF2201 PF09967.9 KKK41144.1 - 0.062 13.5 0.2 0.25 11.5 0.0 2.1 2 1 0 2 2 2 0 VWA-like domain (DUF2201) DUF1374 PF07118.11 KKK41144.1 - 0.24 11.9 11.1 0.086 13.4 6.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) DUF948 PF06103.11 KKK41144.1 - 1 9.7 8.2 2.3 8.5 0.1 4.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) BRX_N PF13713.6 KKK41144.1 - 1.4 8.7 5.2 0.28 11.0 0.5 2.4 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain TPR_1 PF00515.28 KKK41145.1 - 0.073 12.9 0.2 0.21 11.5 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK41145.1 - 0.14 12.4 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DFP PF04127.15 KKK41146.1 - 1.9e-56 190.8 1.0 4.2e-55 186.5 0.3 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 KKK41146.1 - 1.3e-34 119.3 1.5 1.3e-34 119.3 1.5 1.6 2 0 0 2 2 2 1 Flavoprotein HEAT_2 PF13646.6 KKK41147.1 - 8.2e-73 240.9 20.4 6.1e-17 61.8 0.3 6.5 2 2 4 6 6 6 6 HEAT repeats HEAT PF02985.22 KKK41147.1 - 9.8e-55 177.8 2.1 0.00078 19.5 0.0 12.5 12 0 0 12 12 12 11 HEAT repeat HEAT_EZ PF13513.6 KKK41147.1 - 5.2e-27 93.9 10.1 0.025 15.1 0.0 12.1 10 2 2 12 12 12 7 HEAT-like repeat Cnd1 PF12717.7 KKK41147.1 - 2.6e-25 89.4 42.1 1.8e-06 28.1 0.4 10.7 3 1 7 10 10 10 6 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KKK41147.1 - 1.7e-13 49.8 0.0 8.7 7.3 0.0 10.1 10 0 0 10 10 10 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KKK41147.1 - 1.5e-12 47.7 9.0 0.019 15.2 0.4 7.2 1 1 3 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KKK41147.1 - 6.5e-12 45.1 0.2 8.1 6.6 0.0 9.9 11 0 0 11 11 9 0 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 KKK41147.1 - 1.1e-11 44.9 4.7 0.00042 20.1 0.2 5.2 1 1 4 5 5 5 4 DNA alkylation repair enzyme AAA_16 PF13191.6 KKK41147.1 - 1.2e-05 25.8 1.9 0.00025 21.5 0.1 3.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KKK41147.1 - 2.7e-05 24.1 0.0 9.8e-05 22.3 0.0 2.1 1 0 0 1 1 1 1 NACHT domain GUN4_N PF16416.5 KKK41147.1 - 4.6e-05 23.3 6.6 7.3 6.7 0.1 6.2 2 1 3 6 6 6 0 ARM-like repeat domain, GUN4-N terminal ATPase_2 PF01637.18 KKK41147.1 - 6.4e-05 23.0 3.5 6.4e-05 23.0 3.5 4.3 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea Flg_hook PF02120.16 KKK41147.1 - 0.00031 20.6 8.1 5.7 6.9 0.0 7.9 9 0 0 9 9 9 1 Flagellar hook-length control protein FliK RsgA_GTPase PF03193.16 KKK41147.1 - 0.00079 19.4 2.9 0.023 14.6 0.1 3.8 3 0 0 3 3 3 1 RsgA GTPase HD PF01966.22 KKK41147.1 - 0.042 14.1 0.2 0.17 12.1 0.2 2.1 1 0 0 1 1 1 0 HD domain VAD1-2 PF15310.6 KKK41147.1 - 0.052 13.4 10.0 18 5.1 0.0 5.7 4 2 1 6 6 6 0 Vitamin A-deficiency (VAD) rat model signalling DUF4042 PF13251.6 KKK41147.1 - 0.076 12.7 4.3 16 5.1 0.1 5.5 2 2 3 7 7 7 0 Domain of unknown function (DUF4042) AAA_18 PF13238.6 KKK41147.1 - 0.078 13.5 0.1 1.8 9.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KKK41147.1 - 0.12 12.1 0.1 5.3 6.8 0.1 3.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KKK41147.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KKK41147.1 - 0.17 11.6 0.3 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain 23ISL PF16620.5 KKK41147.1 - 0.23 11.7 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 Unstructured linker between I-set domains 2 and 3 on MYLCK AAA_22 PF13401.6 KKK41147.1 - 1.4 9.2 4.0 6.5 7.0 2.0 3.1 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.14 KKK41147.1 - 2.3 8.2 7.8 41 4.2 0.0 4.8 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) PC_rep PF01851.22 KKK41147.1 - 9.3 6.9 11.5 1.8e+02 2.8 0.0 7.2 9 0 0 9 9 6 0 Proteasome/cyclosome repeat Topo-VIb_trans PF09239.11 KKK41149.1 - 4.5e-29 101.3 0.1 4.2e-28 98.2 0.0 2.6 2 0 0 2 2 2 1 Topoisomerase VI B subunit, transducer Rho_N PF07498.12 KKK41149.1 - 3.7e-06 26.8 0.0 1.6e-05 24.7 0.0 2.2 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain HATPase_c_3 PF13589.6 KKK41149.1 - 8e-05 22.5 0.3 0.0012 18.7 0.0 2.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAP PF02037.27 KKK41149.1 - 0.0016 18.2 0.0 0.0042 16.8 0.0 1.8 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.9 KKK41149.1 - 0.079 13.3 0.6 0.41 11.0 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF4208 PF13907.6 KKK41149.1 - 0.42 11.1 0.0 0.42 11.1 0.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) TP6A_N PF04406.14 KKK41150.1 - 1.9e-17 63.0 0.6 3.4e-17 62.2 0.6 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RGS PF00615.19 KKK41151.1 - 0.058 13.7 2.4 0.097 12.9 2.4 1.6 1 1 0 1 1 1 0 Regulator of G protein signaling domain RTX_C PF08339.10 KKK41151.1 - 0.13 12.4 7.6 0.13 12.4 5.6 2.0 1 1 1 2 2 2 0 RTX C-terminal domain HEAT_2 PF13646.6 KKK41153.1 - 6.8e-25 87.3 0.0 2.6e-06 27.7 0.0 7.8 4 1 6 10 10 10 5 HEAT repeats HEAT PF02985.22 KKK41153.1 - 9e-24 81.5 0.0 0.0017 18.5 0.0 12.4 14 0 0 14 14 13 4 HEAT repeat Cnd1 PF12717.7 KKK41153.1 - 4.7e-10 39.7 23.7 3.8e-06 27.0 0.1 5.9 3 2 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KKK41153.1 - 7.9e-07 29.5 0.0 3.9 8.1 0.0 7.1 10 0 0 10 10 8 1 HEAT-like repeat CLASP_N PF12348.8 KKK41153.1 - 0.00017 21.2 2.7 0.078 12.5 0.3 4.1 3 2 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 KKK41153.1 - 0.00058 20.0 2.8 8.3 6.6 0.0 6.3 3 2 3 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KKK41153.1 - 0.0056 16.7 0.0 1.7 8.8 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF1561 PF07598.11 KKK41153.1 - 0.0081 14.4 0.0 0.015 13.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1561) RPN6_N PF18055.1 KKK41153.1 - 0.027 14.8 2.5 5.3 7.4 0.9 3.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Cohesin_HEAT PF12765.7 KKK41153.1 - 0.097 13.0 1.4 5.5 7.4 0.0 4.4 5 1 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion DNA_alkylation PF08713.11 KKK41153.1 - 0.11 12.2 1.8 0.79 9.4 0.2 2.9 2 1 1 3 3 3 0 DNA alkylation repair enzyme CbiA PF01656.23 KKK41153.1 - 2.1 8.4 4.9 7 6.7 2.0 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MCM PF00493.23 KKK41154.1 - 7e-90 300.0 0.0 1e-89 299.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KKK41154.1 - 1.3e-38 131.7 0.0 2.2e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KKK41154.1 - 6.1e-26 90.7 0.4 1.2e-25 89.8 0.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KKK41154.1 - 7.5e-09 35.3 0.1 1.5e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KKK41154.1 - 7.5e-08 32.9 1.1 2.7e-07 31.1 0.3 2.3 3 0 0 3 3 2 1 MCM N-terminal domain AAA_5 PF07728.14 KKK41154.1 - 2.6e-06 27.5 0.3 1.8e-05 24.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KKK41154.1 - 0.00014 21.6 1.2 0.0029 17.3 1.2 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KKK41154.1 - 0.00043 20.2 0.2 0.0013 18.5 0.2 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKK41154.1 - 0.0032 17.2 2.1 0.0072 16.1 2.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_lid_2 PF17863.1 KKK41154.1 - 0.014 15.2 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA lid domain AAA PF00004.29 KKK41154.1 - 0.042 14.3 0.2 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK41154.1 - 0.049 14.0 1.5 0.97 9.8 1.1 2.9 1 1 0 2 2 2 0 AAA ATPase domain Zn-ribbon_8 PF09723.10 KKK41154.1 - 0.09 12.9 0.7 0.2 11.8 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF3987 PF13148.6 KKK41154.1 - 0.09 11.8 0.0 0.43 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_19 PF13245.6 KKK41154.1 - 0.17 12.2 0.4 1.1 9.6 0.0 2.1 1 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK41154.1 - 0.23 10.8 0.9 4 6.7 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ras PF00071.22 KKK41155.1 - 2.8e-39 134.3 0.1 3.2e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK41155.1 - 1.6e-28 99.4 0.0 2.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41155.1 - 5.7e-14 51.9 0.1 7.5e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK41155.1 - 8.6e-07 28.5 0.1 1e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK41155.1 - 7.5e-06 26.0 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK41155.1 - 9.1e-05 22.0 0.1 0.00016 21.2 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKK41155.1 - 0.0021 18.0 0.2 0.71 9.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KKK41155.1 - 0.024 15.0 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KKK41155.1 - 0.035 13.8 0.1 0.049 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KKK41155.1 - 0.058 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KKK41155.1 - 0.069 13.4 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hist_deacetyl PF00850.19 KKK41156.1 - 4e-77 259.7 0.0 4.7e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain ATG16 PF08614.11 KKK41157.1 - 7.2e-07 29.6 26.2 0.0003 21.1 12.2 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) EzrA PF06160.12 KKK41157.1 - 8.9e-06 24.2 12.1 1.3e-05 23.7 12.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA AAA_13 PF13166.6 KKK41157.1 - 9.7e-06 24.5 14.2 1.3e-05 24.1 14.2 1.0 1 0 0 1 1 1 1 AAA domain DUF4407 PF14362.6 KKK41157.1 - 1.6e-05 24.4 12.8 2.3e-05 23.9 12.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF3450 PF11932.8 KKK41157.1 - 1.8e-05 24.2 29.0 0.0016 17.8 13.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 KKK41157.1 - 2.7e-05 24.2 24.2 0.00032 20.7 17.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 KKK41157.1 - 4.1e-05 23.7 16.9 5.9e-05 23.2 16.9 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 KKK41157.1 - 4.1e-05 23.7 27.2 0.00044 20.4 18.6 2.2 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 KKK41157.1 - 4.5e-05 23.7 27.4 0.094 13.1 6.4 4.1 1 1 3 4 4 4 3 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 KKK41157.1 - 8.1e-05 22.3 6.1 0.00013 21.7 6.1 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Spc7 PF08317.11 KKK41157.1 - 9.2e-05 21.5 24.2 0.0027 16.6 15.5 1.9 1 1 0 1 1 1 1 Spc7 kinetochore protein IFT57 PF10498.9 KKK41157.1 - 9.3e-05 21.5 21.6 0.00013 21.0 21.6 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Fez1 PF06818.15 KKK41157.1 - 0.00011 22.7 22.4 0.00025 21.5 22.3 1.4 1 1 0 1 1 1 1 Fez1 CCDC144C PF14915.6 KKK41157.1 - 0.00013 21.2 21.1 0.00024 20.3 21.1 1.5 1 1 0 1 1 1 1 CCDC144C protein coiled-coil region Cast PF10174.9 KKK41157.1 - 0.00014 20.2 18.5 0.00052 18.4 18.6 1.5 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone KASH_CCD PF14662.6 KKK41157.1 - 0.00017 21.5 24.5 0.0016 18.3 10.6 2.0 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KKK41157.1 - 0.00017 21.0 26.5 0.00095 18.6 26.5 1.9 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding HrpB7 PF09486.10 KKK41157.1 - 0.00017 22.0 8.0 0.011 16.1 1.1 2.1 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) LPP PF04728.13 KKK41157.1 - 0.00026 21.3 17.5 0.08 13.3 1.2 3.3 2 1 1 3 3 3 2 Lipoprotein leucine-zipper SHE3 PF17078.5 KKK41157.1 - 0.00027 20.7 19.3 0.00061 19.6 19.3 1.5 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Atg14 PF10186.9 KKK41157.1 - 0.00029 20.0 19.7 0.0041 16.2 7.2 2.1 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 KKK41157.1 - 0.00046 19.8 25.1 0.0094 15.6 9.2 2.1 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Myosin_tail_1 PF01576.19 KKK41157.1 - 0.00051 18.0 17.5 0.00083 17.3 17.5 1.2 1 0 0 1 1 1 1 Myosin tail FlaC_arch PF05377.11 KKK41157.1 - 0.00053 20.3 19.0 0.36 11.3 2.5 3.8 1 1 1 3 3 3 1 Flagella accessory protein C (FlaC) FPP PF05911.11 KKK41157.1 - 0.00053 18.3 24.8 0.001 17.4 24.0 1.5 1 1 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF641 PF04859.12 KKK41157.1 - 0.00064 20.1 19.4 0.043 14.2 6.4 3.1 1 1 2 3 3 3 2 Plant protein of unknown function (DUF641) HMMR_C PF15908.5 KKK41157.1 - 0.00064 20.0 13.7 0.00095 19.5 13.7 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal APG6_N PF17675.1 KKK41157.1 - 0.00067 20.2 14.3 0.00067 20.2 14.3 2.1 1 1 1 2 2 2 2 Apg6 coiled-coil region DUF2353 PF09789.9 KKK41157.1 - 0.00075 18.9 13.5 0.0011 18.4 13.5 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Phage_GP20 PF06810.11 KKK41157.1 - 0.00084 19.2 21.6 0.003 17.4 10.0 2.4 1 1 1 2 2 2 1 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 KKK41157.1 - 0.00086 19.4 32.4 0.0043 17.1 16.3 3.1 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 KKK41157.1 - 0.00092 16.9 14.8 0.0012 16.6 14.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4763 PF15960.5 KKK41157.1 - 0.00097 18.5 27.7 0.065 12.5 8.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4763) Tropomyosin_1 PF12718.7 KKK41157.1 - 0.0012 19.0 23.0 0.041 14.0 9.2 2.5 1 1 1 2 2 2 2 Tropomyosin like FUSC PF04632.12 KKK41157.1 - 0.0015 17.2 4.3 0.002 16.8 4.3 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family ZapB PF06005.12 KKK41157.1 - 0.0016 18.9 32.8 0.04 14.4 10.8 3.2 1 1 2 3 3 3 2 Cell division protein ZapB HOOK PF05622.12 KKK41157.1 - 0.0017 16.6 20.1 0.0027 16.0 20.1 1.2 1 0 0 1 1 1 1 HOOK protein AIP3 PF03915.13 KKK41157.1 - 0.0018 17.5 7.5 0.0024 17.0 7.5 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF724 PF05266.14 KKK41157.1 - 0.0019 18.1 17.5 0.062 13.1 17.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF724) CC2-LZ PF16516.5 KKK41157.1 - 0.0019 18.5 19.9 0.068 13.5 11.0 2.4 1 1 1 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Leu_zip PF15294.6 KKK41157.1 - 0.002 17.7 17.1 0.016 14.7 15.8 1.9 1 1 0 1 1 1 1 Leucine zipper TMF_TATA_bd PF12325.8 KKK41157.1 - 0.0021 18.3 21.9 0.0053 17.0 15.1 2.2 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding HAP1_N PF04849.13 KKK41157.1 - 0.0022 17.3 25.7 0.015 14.5 24.5 1.9 1 1 0 1 1 1 1 HAP1 N-terminal conserved region COG7 PF10191.9 KKK41157.1 - 0.0025 16.2 10.4 0.0032 15.8 10.4 1.1 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) PspA_IM30 PF04012.12 KKK41157.1 - 0.0025 17.4 22.5 0.12 12.0 8.1 3.0 1 1 2 3 3 3 1 PspA/IM30 family DUF4200 PF13863.6 KKK41157.1 - 0.0029 18.0 2.6 0.0029 18.0 2.6 3.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4200) LUC7 PF03194.15 KKK41157.1 - 0.003 17.2 6.3 0.0051 16.5 6.3 1.3 1 0 0 1 1 1 1 LUC7 N_terminus HMMR_N PF15905.5 KKK41157.1 - 0.0033 16.9 21.8 0.0049 16.4 21.8 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal FAM76 PF16046.5 KKK41157.1 - 0.0034 16.8 19.7 0.012 15.0 14.2 2.2 1 1 1 2 2 2 1 FAM76 protein CALCOCO1 PF07888.11 KKK41157.1 - 0.0035 16.3 15.7 0.0051 15.7 15.7 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 KKK41157.1 - 0.0035 17.4 16.5 0.064 13.3 4.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DHR10 PF18595.1 KKK41157.1 - 0.0036 17.4 25.4 0.24 11.4 10.8 2.2 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain DUF5082 PF16888.5 KKK41157.1 - 0.0036 17.6 25.4 0.18 12.1 25.7 3.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) V_ATPase_I PF01496.19 KKK41157.1 - 0.0048 14.9 10.1 0.0064 14.5 10.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cluap1 PF10234.9 KKK41157.1 - 0.0051 16.3 22.4 0.26 10.6 9.2 2.3 1 1 1 2 2 2 2 Clusterin-associated protein-1 CEP63 PF17045.5 KKK41157.1 - 0.0051 16.7 17.4 0.0081 16.1 17.4 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa MAD PF05557.13 KKK41157.1 - 0.0051 15.2 22.4 0.0087 14.5 22.4 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Golgin_A5 PF09787.9 KKK41157.1 - 0.0055 16.2 21.3 0.01 15.4 21.3 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 Phage_Mu_Gam PF07352.12 KKK41157.1 - 0.0057 16.6 6.3 0.0057 16.6 6.3 2.2 1 1 1 2 2 2 1 Bacteriophage Mu Gam like protein Laminin_I PF06008.14 KKK41157.1 - 0.0062 16.3 21.2 0.0094 15.7 21.2 1.2 1 0 0 1 1 1 1 Laminin Domain I CENP-H PF05837.12 KKK41157.1 - 0.0063 16.9 23.4 0.018 15.5 14.5 2.2 1 1 1 2 2 2 1 Centromere protein H (CENP-H) Jnk-SapK_ap_N PF09744.9 KKK41157.1 - 0.0072 16.6 22.4 0.018 15.3 22.4 1.7 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 YabA PF06156.13 KKK41157.1 - 0.0077 16.9 22.3 0.5 11.0 15.9 3.1 1 1 1 2 2 2 1 Initiation control protein YabA FmiP_Thoc5 PF09766.9 KKK41157.1 - 0.0086 15.4 10.0 0.0086 15.4 10.0 2.2 1 1 1 2 2 2 1 Fms-interacting protein/Thoc5 DivIC PF04977.15 KKK41157.1 - 0.0089 15.8 28.9 0.26 11.1 7.4 3.4 1 1 2 3 3 3 1 Septum formation initiator Filament PF00038.21 KKK41157.1 - 0.009 15.6 22.2 0.086 12.4 22.2 1.9 1 1 0 1 1 1 1 Intermediate filament protein WEMBL PF05701.11 KKK41157.1 - 0.0091 14.7 17.9 0.044 12.5 18.0 1.8 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Taxilin PF09728.9 KKK41157.1 - 0.0093 15.2 19.1 0.014 14.6 19.1 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF812 PF05667.11 KKK41157.1 - 0.011 14.7 26.6 0.048 12.6 26.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Lebercilin PF15619.6 KKK41157.1 - 0.012 15.2 25.1 0.17 11.5 25.1 2.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TSNAXIP1_N PF15739.5 KKK41157.1 - 0.013 15.9 4.9 0.013 15.9 4.9 2.2 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus MbeD_MobD PF04899.12 KKK41157.1 - 0.013 15.6 18.9 0.041 14.0 4.7 3.1 1 1 2 3 3 3 0 MbeD/MobD like FlxA PF14282.6 KKK41157.1 - 0.014 15.4 44.9 0.13 12.3 22.4 2.4 1 1 1 2 2 2 0 FlxA-like protein SPATA24 PF15175.6 KKK41157.1 - 0.014 15.3 17.8 0.18 11.7 5.1 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 ABC_tran_CTD PF16326.5 KKK41157.1 - 0.015 15.6 21.6 1.8 8.9 11.5 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Tektin PF03148.14 KKK41157.1 - 0.015 14.0 20.3 0.55 8.9 20.2 2.1 1 1 0 1 1 1 0 Tektin family MscS_porin PF12795.7 KKK41157.1 - 0.016 14.8 35.5 0.028 13.9 35.5 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Sec2p PF06428.11 KKK41157.1 - 0.016 15.1 28.1 0.63 10.0 2.2 3.7 1 1 3 4 4 4 0 GDP/GTP exchange factor Sec2p DUF4795 PF16043.5 KKK41157.1 - 0.016 14.8 24.4 0.37 10.4 9.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 KKK41157.1 - 0.017 15.8 30.6 0.08 13.6 4.5 4.5 1 1 3 4 4 4 0 SlyX COG6 PF06419.11 KKK41157.1 - 0.017 13.4 16.0 0.029 12.6 15.5 1.6 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 Prefoldin PF02996.17 KKK41157.1 - 0.017 15.0 23.5 0.41 10.6 3.5 3.4 2 1 1 3 3 3 0 Prefoldin subunit Laminin_II PF06009.12 KKK41157.1 - 0.018 15.0 16.4 0.033 14.2 15.6 1.7 1 1 1 2 2 2 0 Laminin Domain II DUF4140 PF13600.6 KKK41157.1 - 0.021 15.3 14.7 0.067 13.6 5.1 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.13 KKK41157.1 - 0.021 14.1 22.2 0.1 11.8 9.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein Swi5 PF07061.11 KKK41157.1 - 0.022 14.9 25.0 4.3 7.5 7.1 3.3 1 1 1 2 2 2 0 Swi5 Lipoprotein_6 PF01441.19 KKK41157.1 - 0.023 14.7 5.6 0.028 14.4 5.1 1.3 1 1 0 1 1 1 0 Lipoprotein SCP-1 PF05483.12 KKK41157.1 - 0.026 12.5 14.3 0.035 12.1 14.3 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) OmpH PF03938.14 KKK41157.1 - 0.027 14.8 25.0 0.041 14.2 24.0 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 KKK41157.1 - 0.027 14.6 28.9 0.13 12.3 28.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 KKK41157.1 - 0.028 14.4 31.6 3 7.8 8.2 3.6 1 1 3 4 4 4 0 Prefoldin subunit CENP-Q PF13094.6 KKK41157.1 - 0.032 14.4 19.2 0.47 10.6 6.9 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Uso1_p115_C PF04871.13 KKK41157.1 - 0.034 14.5 23.0 0.034 14.5 14.6 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prominin PF05478.11 KKK41157.1 - 0.034 12.1 18.9 0.089 10.7 18.9 1.5 1 1 0 1 1 1 0 Prominin bZIP_1 PF00170.21 KKK41157.1 - 0.035 14.2 20.7 0.046 13.8 1.7 3.8 1 1 4 5 5 4 0 bZIP transcription factor CENP-K PF11802.8 KKK41157.1 - 0.038 13.6 16.8 0.058 13.0 16.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K TMF_DNA_bd PF12329.8 KKK41157.1 - 0.041 13.9 29.3 1.1 9.3 14.6 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding PEARLI-4 PF05278.12 KKK41157.1 - 0.042 13.5 7.3 1.6 8.2 1.0 2.2 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) BRE1 PF08647.11 KKK41157.1 - 0.042 13.9 22.8 0.054 13.6 6.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 KKK41157.1 - 0.043 12.4 19.5 0.073 11.6 19.3 1.4 1 1 0 1 1 1 0 Macoilin family DUF4201 PF13870.6 KKK41157.1 - 0.052 13.3 24.5 0.56 9.9 24.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Cnn_1N PF07989.11 KKK41157.1 - 0.055 13.6 23.1 0.065 13.4 9.5 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 NPV_P10 PF05531.12 KKK41157.1 - 0.058 13.9 20.3 0.12 12.8 7.0 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Gp58 PF07902.11 KKK41157.1 - 0.064 11.5 15.9 0.086 11.1 15.9 1.1 1 0 0 1 1 1 0 gp58-like protein Spc24 PF08286.11 KKK41157.1 - 0.07 13.4 26.5 5.4 7.3 5.6 3.3 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Hemagglutinin PF00509.18 KKK41157.1 - 0.081 11.3 7.4 0.059 11.8 5.8 1.5 1 1 1 2 2 2 0 Haemagglutinin DUF2046 PF09755.9 KKK41157.1 - 0.081 12.1 19.3 0.16 11.2 8.4 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) GOLGA2L5 PF15070.6 KKK41157.1 - 0.081 11.6 21.0 0.056 12.1 7.1 2.1 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF2968 PF11180.8 KKK41157.1 - 0.088 12.4 29.4 0.36 10.5 26.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Syntaxin-6_N PF09177.11 KKK41157.1 - 0.094 13.3 12.5 1.4e+02 3.1 12.5 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HemX PF04375.14 KKK41157.1 - 0.095 12.0 30.1 0.12 11.6 14.3 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Vps5 PF09325.10 KKK41157.1 - 0.096 12.2 11.7 0.16 11.5 11.2 1.5 1 1 0 1 1 1 0 Vps5 C terminal like CCDC158 PF15921.5 KKK41157.1 - 0.096 10.5 14.8 0.63 7.8 9.3 2.6 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 158 DLP_helical PF18709.1 KKK41157.1 - 0.11 11.7 13.9 0.44 9.7 0.9 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain Wtap PF17098.5 KKK41157.1 - 0.11 12.4 20.5 0.44 10.5 20.5 2.3 1 1 0 1 1 1 0 WTAP/Mum2p family DUF4686 PF15742.5 KKK41157.1 - 0.11 11.6 32.3 0.37 9.9 32.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Troponin PF00992.20 KKK41157.1 - 0.11 12.8 16.7 1.2 9.5 5.0 2.2 1 1 1 2 2 2 0 Troponin TSC22 PF01166.18 KKK41157.1 - 0.11 12.8 17.5 0.47 10.8 2.9 3.8 1 1 2 3 3 3 0 TSC-22/dip/bun family FliJ PF02050.16 KKK41157.1 - 0.12 12.6 27.6 0.37 11.0 22.4 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein DUF2730 PF10805.8 KKK41157.1 - 0.15 12.2 15.6 1.3 9.1 5.4 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) Seryl_tRNA_N PF02403.22 KKK41157.1 - 0.15 12.3 19.3 0.24 11.6 8.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PI3K_P85_iSH2 PF16454.5 KKK41157.1 - 0.15 11.6 24.3 1.2 8.8 24.6 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain zinc_ribbon_2 PF13240.6 KKK41157.1 - 0.16 11.7 3.8 3.5 7.5 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DivIVA PF05103.13 KKK41157.1 - 0.2 11.8 20.9 1.1 9.3 1.9 3.0 1 1 2 3 3 3 0 DivIVA protein A2L_zn_ribbon PF08792.10 KKK41157.1 - 0.21 11.3 1.0 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain TACC_C PF05010.14 KKK41157.1 - 0.24 11.2 22.2 0.29 10.9 14.3 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YscO-like PF16789.5 KKK41157.1 - 0.26 11.3 12.5 0.7 9.9 8.2 2.1 1 1 1 2 2 2 0 YscO-like protein ADK_lid PF05191.14 KKK41157.1 - 0.27 11.3 3.9 0.98 9.5 3.9 2.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid DUF4618 PF15397.6 KKK41157.1 - 0.27 10.6 25.1 0.8 9.1 6.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) PKcGMP_CC PF16808.5 KKK41157.1 - 0.28 11.1 12.4 3.7 7.5 1.4 4.3 4 1 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase E2F_CC-MB PF16421.5 KKK41157.1 - 0.32 11.4 18.6 0.27 11.6 3.0 3.0 2 1 1 3 3 2 0 E2F transcription factor CC-MB domain zf-ribbon_3 PF13248.6 KKK41157.1 - 0.37 10.3 3.2 1.5 8.4 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF848 PF05852.11 KKK41157.1 - 0.44 10.6 11.3 0.68 10.0 10.0 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CREPT PF16566.5 KKK41157.1 - 0.46 10.7 18.7 1.8 8.7 18.7 2.0 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour IFT20 PF14931.6 KKK41157.1 - 0.46 10.7 18.9 0.32 11.2 8.6 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Tropomyosin PF00261.20 KKK41157.1 - 0.48 9.8 15.0 0.48 9.7 4.4 2.1 1 1 0 1 1 1 0 Tropomyosin Mating_N PF12731.7 KKK41157.1 - 0.54 10.4 5.9 1.5 9.0 5.6 1.9 1 1 0 1 1 1 0 Mating-type protein beta 1 Sec34 PF04136.15 KKK41157.1 - 0.57 10.1 22.1 3.1 7.7 10.4 2.1 1 1 1 2 2 2 0 Sec34-like family SKA1 PF07160.12 KKK41157.1 - 0.57 10.0 22.0 8.5 6.2 8.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Tho2 PF11262.8 KKK41157.1 - 0.58 9.3 19.4 0.84 8.8 5.1 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 FapA PF03961.13 KKK41157.1 - 0.6 8.7 20.7 0.34 9.5 9.8 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A COG2 PF06148.11 KKK41157.1 - 0.76 9.9 14.2 1.5 9.0 4.1 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.9 KKK41157.1 - 0.76 10.1 21.0 1 9.7 8.2 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KKK41157.1 - 0.8 10.0 14.4 2.1 8.7 6.1 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.9 KKK41157.1 - 0.8 9.9 17.2 0.99 9.6 13.3 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Yuri_gagarin PF15934.5 KKK41157.1 - 0.81 9.5 17.3 1.9 8.3 17.3 1.4 1 1 0 1 1 1 0 Yuri gagarin DUF2205 PF10224.9 KKK41157.1 - 0.81 9.7 21.8 1.6 8.8 10.8 3.1 1 1 2 3 3 2 0 Short coiled-coil protein DUF16 PF01519.16 KKK41157.1 - 0.83 10.2 24.3 3.7 8.1 8.8 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 KKK41157.1 - 0.92 10.0 26.4 4.5 7.8 9.2 2.5 1 1 1 2 2 2 0 Snapin/Pallidin MCC-bdg_PDZ PF10506.9 KKK41157.1 - 0.99 9.5 17.7 0.8 9.8 1.7 3.9 2 2 2 4 4 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome JIP_LZII PF16471.5 KKK41157.1 - 1.2 9.4 18.4 4.2 7.6 7.6 3.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II ERM PF00769.19 KKK41157.1 - 1.2 8.9 22.0 5 6.9 7.2 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family APC_N_CC PF16689.5 KKK41157.1 - 1.2 9.2 19.3 0.65 10.1 1.4 3.3 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Cep57_CLD_2 PF14197.6 KKK41157.1 - 1.3 9.2 19.4 5.7 7.1 11.5 3.1 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 LMBR1 PF04791.16 KKK41157.1 - 1.4 7.8 9.9 2 7.2 9.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein THOC7 PF05615.13 KKK41157.1 - 1.4 9.2 19.3 11 6.3 12.5 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 betaPIX_CC PF16523.5 KKK41157.1 - 1.4 8.8 9.9 2.8 7.8 1.1 2.5 1 1 1 2 2 2 0 betaPIX coiled coil Muted PF14942.6 KKK41157.1 - 1.4 9.2 23.5 1.1 9.6 15.8 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1465 PF07323.12 KKK41157.1 - 1.5 8.7 11.2 0.96 9.3 8.5 1.9 1 1 1 2 2 1 0 Protein of unknown function (DUF1465) GrpE PF01025.19 KKK41157.1 - 1.5 8.5 20.7 2.9 7.5 5.0 2.4 1 1 1 2 2 2 0 GrpE MIP-T3_C PF17749.1 KKK41157.1 - 1.5 8.7 22.8 3.8 7.5 22.8 1.6 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Herpes_UL6 PF01763.16 KKK41157.1 - 1.7 7.1 18.0 8.8 4.7 16.4 1.9 1 1 1 2 2 2 0 Herpesvirus UL6 like APG17 PF04108.12 KKK41157.1 - 1.7 7.7 18.0 0.59 9.2 8.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg17 LRRFIP PF09738.9 KKK41157.1 - 1.7 8.0 20.3 4.4 6.7 20.4 1.5 1 1 0 1 1 1 0 LRRFIP family GIT_CC PF16559.5 KKK41157.1 - 2 8.4 32.5 1.5 8.7 12.1 3.5 1 1 3 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4164 PF13747.6 KKK41157.1 - 2.1 8.6 10.5 7.1 7.0 2.7 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) CLZ PF16526.5 KKK41157.1 - 2.2 8.7 21.3 18 5.7 1.8 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PRKG1_interact PF15898.5 KKK41157.1 - 2.3 9.2 23.9 0.36 11.8 10.7 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CCDC-167 PF15188.6 KKK41157.1 - 2.4 8.6 19.1 0.17 12.2 8.8 2.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 TolA_bind_tri PF16331.5 KKK41157.1 - 2.6 8.2 33.3 28 4.9 13.3 3.2 1 1 1 2 2 2 0 TolA binding protein trimerisation DNA_topoisoIV PF00521.20 KKK41157.1 - 2.8 6.8 12.2 3.9 6.3 12.2 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A TPD52 PF04201.15 KKK41157.1 - 2.8 7.5 13.6 0.56 9.8 4.0 2.2 1 1 1 2 2 2 0 Tumour protein D52 family DUF773 PF05600.12 KKK41157.1 - 2.8 6.5 21.0 73 1.9 21.1 2.0 1 1 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Fib_alpha PF08702.10 KKK41157.1 - 2.9 8.1 24.7 0.84 9.8 14.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CCDC106 PF15794.5 KKK41157.1 - 3 7.5 14.1 0.72 9.5 0.3 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 FemAB PF02388.16 KKK41157.1 - 3 6.6 20.1 1.6 7.5 8.1 2.1 1 1 1 2 2 2 0 FemAB family Spc42p PF11544.8 KKK41157.1 - 3.2 7.8 17.7 0.46 10.5 11.1 2.6 1 1 1 2 2 1 0 Spindle pole body component Spc42p Cob_adeno_trans PF01923.18 KKK41157.1 - 3.7 7.7 13.0 1.8 8.7 4.3 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase KLRAQ PF10205.9 KKK41157.1 - 3.9 7.8 19.4 13 6.1 14.3 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Fmp27_WPPW PF10359.9 KKK41157.1 - 4 6.2 20.7 35 3.1 20.7 1.9 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CP12 PF02672.15 KKK41157.1 - 4 8.3 5.5 1.6 9.6 1.1 2.4 1 1 1 2 2 2 0 CP12 domain YscO PF07321.12 KKK41157.1 - 4.3 7.3 16.9 2.4 8.1 10.0 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO Occludin_ELL PF07303.13 KKK41157.1 - 4.4 8.1 15.5 6.2 7.6 5.7 2.2 1 1 1 2 2 2 0 Occludin homology domain FliD_C PF07195.12 KKK41157.1 - 4.9 6.5 22.2 6.3 6.1 11.3 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CorA PF01544.18 KKK41157.1 - 5 6.4 12.0 7.8 5.7 11.1 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Nnf1 PF03980.14 KKK41157.1 - 5.8 7.3 21.2 4.4 7.7 2.2 3.4 1 1 2 3 3 3 0 Nnf1 DUF745 PF05335.13 KKK41157.1 - 5.8 6.6 20.1 12 5.5 20.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Mod_r PF07200.13 KKK41157.1 - 6.5 6.9 27.3 5.9 7.0 17.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2009 PF09418.10 KKK41157.1 - 6.5 5.7 10.0 8.6 5.3 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Sulfatase_C PF14707.6 KKK41157.1 - 6.6 7.5 10.4 6.1 7.6 2.3 3.0 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DUF2203 PF09969.9 KKK41157.1 - 7.1 7.4 15.0 5.8 7.7 5.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Phage_GPO PF05929.11 KKK41157.1 - 7.7 6.0 17.9 68 3.0 17.9 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4988 PF16378.5 KKK41157.1 - 8.9 5.9 12.7 2.9 7.5 0.6 3.0 2 1 0 2 2 2 0 Domain of unknown function HlyD_2 PF12700.7 KKK41157.1 - 9.1 4.9 17.3 4.3 6.0 1.0 1.5 1 1 1 2 2 2 0 HlyD family secretion protein HIP1_clath_bdg PF16515.5 KKK41157.1 - 9.1 7.0 28.5 22 5.7 14.9 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SpecificRecomb PF10136.9 KKK41157.1 - 9.6 4.4 9.2 13 4.0 9.2 1.0 1 0 0 1 1 1 0 Site-specific recombinase Phage_lysis PF03245.13 KKK41157.1 - 9.8 6.3 17.5 0.69 10.0 5.7 2.6 1 1 2 3 3 3 0 Bacteriophage Rz lysis protein DUF4337 PF14235.6 KKK41157.1 - 10 6.2 14.1 2.9 8.0 9.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Transglut_core PF01841.19 KKK41158.1 - 4.4e-11 43.2 0.0 8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Big_3_5 PF16640.5 KKK41158.1 - 4.6e-07 29.9 14.1 0.011 15.9 2.3 5.5 5 0 0 5 5 5 2 Bacterial Ig-like domain (group 3) MgtE_N PF03448.17 KKK41158.1 - 0.00028 21.5 0.6 0.00058 20.4 0.6 1.4 1 0 0 1 1 1 1 MgtE intracellular N domain PEGA PF08308.11 KKK41158.1 - 0.028 14.3 0.0 0.63 10.0 0.0 3.1 3 0 0 3 3 3 0 PEGA domain CarboxypepD_reg PF13620.6 KKK41159.1 - 0.0025 18.0 1.5 1.7 8.9 0.5 3.3 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain TIG PF01833.24 KKK41159.1 - 0.035 14.2 6.0 0.029 14.4 2.3 2.5 2 0 0 2 2 2 0 IPT/TIG domain Big_1 PF02369.16 KKK41159.1 - 0.096 12.7 6.5 3.2 7.8 0.1 3.5 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 1) Cadherin_5 PF17892.1 KKK41159.1 - 0.17 11.8 2.2 0.23 11.4 0.3 2.3 2 0 0 2 2 2 0 Cadherin-like domain TctB PF07331.11 KKK41161.1 - 0.00044 20.5 0.4 0.0012 19.1 0.4 1.8 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Na_H_Exchanger PF00999.21 KKK41161.1 - 0.0036 16.2 3.4 0.0036 16.2 3.4 1.6 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Tmemb_185A PF10269.9 KKK41161.1 - 0.024 14.3 2.1 0.048 13.3 2.1 1.5 1 1 0 1 1 1 0 Transmembrane Fragile-X-F protein Ni_hydr_CYTB PF01292.20 KKK41161.1 - 0.093 12.3 0.5 1.1 8.8 0.3 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 AgrB PF04647.15 KKK41161.1 - 2.6 7.3 13.0 34 3.7 11.8 2.7 2 1 1 3 3 3 0 Accessory gene regulator B HGD-D PF06050.13 KKK41163.1 - 8.9e-36 124.3 0.0 1.1e-35 124.0 0.0 1.1 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component BcrAD_BadFG PF01869.20 KKK41164.1 - 1.3e-28 100.2 0.2 1.5e-28 100.1 0.2 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M22 PF00814.25 KKK41164.1 - 0.0078 15.9 0.0 0.0078 15.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family TGS PF02824.21 KKK41164.1 - 0.084 12.9 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 TGS domain Glucosamine_iso PF01182.20 KKK41164.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase BcrAD_BadFG PF01869.20 KKK41165.1 - 1.1e-19 71.0 0.1 1.3e-19 70.7 0.1 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 KKK41165.1 - 0.0054 16.3 0.1 0.79 9.2 0.1 2.1 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FtsA PF14450.6 KKK41165.1 - 0.097 13.1 0.9 1.4 9.4 0.1 2.3 2 1 0 2 2 2 0 Cell division protein FtsA VIT1 PF01988.19 KKK41166.1 - 1.4e-10 41.4 11.0 7.4e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 VIT family DUF2207 PF09972.9 KKK41166.1 - 0.018 13.8 3.5 0.82 8.4 3.5 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ECH_1 PF00378.20 KKK41167.1 - 4e-42 144.3 0.0 4.4e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK41167.1 - 6e-10 39.1 0.3 1.4e-09 37.9 0.3 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribosomal_L30 PF00327.20 KKK41171.1 - 4.2e-07 29.8 2.5 7.1e-07 29.0 0.1 2.4 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e Ribosomal_S5_C PF03719.15 KKK41172.1 - 6.9e-23 79.9 0.0 1.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KKK41172.1 - 1.5e-17 63.3 3.6 2.1e-17 62.8 0.8 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_L5e PF17144.4 KKK41173.1 - 3.7e-26 92.1 0.5 8.4e-21 74.7 0.2 2.3 1 1 1 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KKK41173.1 - 2e-07 31.9 0.4 2e-07 31.9 0.4 1.6 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KKK41173.1 - 1.5e-06 28.5 0.1 2.2e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L19e PF01280.20 KKK41174.1 - 1.4e-51 174.4 14.1 1.5e-51 174.2 14.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e DUF4019 PF13211.6 KKK41174.1 - 0.21 12.0 2.7 0.39 11.1 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4019) Ribosomal_L32e PF01655.18 KKK41175.1 - 0.033 14.6 0.1 0.046 14.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L32 P3A PF08727.11 KKK41175.1 - 0.057 12.8 0.1 0.093 12.1 0.0 1.5 2 0 0 2 2 2 0 Poliovirus 3A protein like VWA_2 PF13519.6 KKK41179.1 - 2.3e-09 37.9 0.1 2.5e-08 34.5 0.0 2.3 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 KKK41179.1 - 2.7e-05 24.5 0.3 6.2e-05 23.3 0.2 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain SRPRB PF09439.10 KKK41179.1 - 0.0011 18.5 0.9 0.002 17.6 0.2 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit VWA_3 PF13768.6 KKK41179.1 - 0.0077 16.2 0.1 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain adh_short PF00106.25 KKK41180.1 - 1.1e-43 149.0 0.1 1.8e-43 148.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK41180.1 - 1.6e-30 106.4 0.0 3.2e-30 105.4 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK41180.1 - 5.6e-08 32.9 0.0 1.2e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK41180.1 - 0.024 14.5 0.1 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_3 PF02655.14 KKK41181.1 - 2.8e-29 102.2 0.0 5.2e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KKK41181.1 - 2.7e-08 33.6 0.0 8.2e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.6 KKK41181.1 - 3.3e-08 33.3 0.0 6.2e-07 29.2 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 KKK41181.1 - 4.2e-07 29.7 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KKK41181.1 - 0.00017 21.1 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 KKK41181.1 - 0.0034 17.0 0.0 0.0095 15.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain TTL PF03133.15 KKK41181.1 - 0.022 13.9 1.0 1.6 7.8 0.2 3.0 3 0 0 3 3 3 0 Tubulin-tyrosine ligase family ATP-grasp PF02222.22 KKK41181.1 - 0.031 13.9 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 KKK41181.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ras PF00071.22 KKK41182.1 - 1e-42 145.5 0.2 1.2e-42 145.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK41182.1 - 1.4e-27 96.3 0.1 1.9e-27 95.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41182.1 - 2.7e-12 46.5 0.4 2.8e-12 46.4 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK41182.1 - 3.9e-05 23.7 0.0 5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK41182.1 - 0.0051 16.3 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK41182.1 - 0.0071 15.7 0.1 0.0093 15.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KKK41182.1 - 0.015 15.3 0.2 0.021 14.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KKK41182.1 - 0.1 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KKK41182.1 - 0.18 11.4 0.2 4.2 6.9 0.2 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Robl_LC7 PF03259.17 KKK41183.1 - 6.3e-06 25.9 0.2 0.0074 16.0 0.0 2.3 2 0 0 2 2 2 2 Roadblock/LC7 domain Bac_DNA_binding PF00216.21 KKK41183.1 - 0.04 14.1 0.1 0.074 13.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein NTP_transferase PF00483.23 KKK41184.1 - 9.2e-27 94.2 0.0 1.3e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KKK41184.1 - 1.3e-09 38.6 0.0 1.8e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KKK41184.1 - 3.1e-05 23.5 0.7 0.00014 21.4 0.1 2.4 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 KKK41184.1 - 0.00024 19.4 0.6 0.00034 18.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KKK41184.1 - 0.009 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase PKcGMP_CC PF16808.5 KKK41185.1 - 2.7e-06 27.1 29.4 0.00025 20.8 1.6 4.1 3 1 1 4 4 4 3 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5600 PF18150.1 KKK41185.1 - 0.0017 18.9 4.5 0.0017 18.9 4.5 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF5600) Tropomyosin_1 PF12718.7 KKK41185.1 - 0.053 13.7 23.9 0.1 12.8 23.9 1.5 1 0 0 1 1 1 0 Tropomyosin like Exonuc_VII_L PF02601.15 KKK41185.1 - 0.23 11.0 11.4 0.33 10.5 11.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 KKK41185.1 - 0.9 9.9 21.5 1.7 9.0 7.4 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 KKK41185.1 - 2.1 8.1 21.5 0.5 10.2 15.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Titin_Ig-rpts PF06582.12 KKK41185.1 - 2.3 8.2 8.1 28 4.8 0.0 3.8 4 0 0 4 4 4 0 Titin repeat SlyX PF04102.12 KKK41185.1 - 3.1 8.5 15.3 2.2 9.0 3.5 2.5 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.6 KKK41185.1 - 3.6 6.9 9.2 5.1 6.4 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) L31 PF09784.9 KKK41185.1 - 3.7 8.0 8.1 21 5.6 2.1 2.5 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 PHP PF02811.19 KKK41186.1 - 1.5e-13 51.4 0.2 3e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 PHP domain PHP_C PF13263.6 KKK41186.1 - 0.02 14.6 0.0 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 PHP-associated Methyltransf_11 PF08241.12 KKK41187.1 - 1.2e-24 86.8 0.0 1.8e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK41187.1 - 2.2e-22 79.6 0.0 3.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK41187.1 - 3.7e-21 75.5 0.0 5.1e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK41187.1 - 1.7e-16 60.8 0.0 2.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK41187.1 - 2.4e-16 60.0 0.0 3.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK41187.1 - 5e-14 52.2 0.0 7.6e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KKK41187.1 - 2.1e-13 50.2 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KKK41187.1 - 4.3e-09 36.2 0.0 6.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KKK41187.1 - 5.4e-09 35.8 0.0 8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KKK41187.1 - 1.7e-08 34.6 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KKK41187.1 - 3.1e-06 26.7 0.6 4.2e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_PK PF05891.12 KKK41187.1 - 1e-05 25.1 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.11 KKK41187.1 - 2e-05 23.7 0.0 2.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 KKK41187.1 - 0.00025 20.7 0.0 0.00033 20.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 KKK41187.1 - 0.0005 19.5 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KKK41187.1 - 0.00059 19.8 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KKK41187.1 - 0.00064 19.4 0.0 0.00092 18.9 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DUF43 PF01861.16 KKK41187.1 - 0.0014 17.9 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_8 PF05148.15 KKK41187.1 - 0.0023 17.8 0.0 0.0094 15.8 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 KKK41187.1 - 0.0029 17.7 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KKK41187.1 - 0.0031 17.0 0.0 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 KKK41187.1 - 0.0084 14.7 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase AdoMet_MTase PF07757.13 KKK41187.1 - 0.013 15.9 1.3 0.059 13.7 1.3 2.0 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N6_N4_Mtase PF01555.18 KKK41187.1 - 0.02 14.6 3.8 0.61 9.7 0.1 2.4 2 1 0 2 2 2 0 DNA methylase N2227 PF07942.12 KKK41187.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 1 1 0 1 1 1 0 N2227-like protein DREV PF05219.12 KKK41187.1 - 0.039 13.1 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.19 KKK41187.1 - 0.043 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KKK41187.1 - 0.046 12.8 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 KKK41187.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KKK41187.1 - 0.15 11.7 0.1 0.15 11.7 0.1 1.6 2 0 0 2 2 1 0 RNA cap guanine-N2 methyltransferase DUF938 PF06080.12 KKK41187.1 - 0.15 11.8 0.0 1.6 8.5 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF938) UPF0020 PF01170.18 KKK41187.1 - 0.23 11.1 0.0 0.4 10.3 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 TPR_1 PF00515.28 KKK41188.1 - 4e-22 77.1 0.5 3e-05 23.6 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKK41188.1 - 1.6e-19 68.4 6.3 0.00087 19.3 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK41188.1 - 3.5e-18 64.2 0.3 8.2e-06 25.6 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK41188.1 - 4e-17 61.3 0.0 0.00015 21.9 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat LRR_8 PF13855.6 KKK41188.1 - 5.8e-13 48.4 15.9 2.7e-08 33.4 0.9 2.7 2 0 0 2 2 2 2 Leucine rich repeat TPR_11 PF13414.6 KKK41188.1 - 8.5e-12 44.6 2.5 0.0015 18.2 0.1 5.3 1 1 4 5 5 5 3 TPR repeat LRR_4 PF12799.7 KKK41188.1 - 1.6e-10 41.1 16.3 3.7e-06 27.2 0.3 3.7 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) TPR_19 PF14559.6 KKK41188.1 - 2.4e-10 40.7 0.0 0.035 14.6 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK41188.1 - 5.3e-09 36.2 0.0 0.0013 18.9 0.0 4.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK41188.1 - 8.4e-09 34.9 0.0 0.04 14.0 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK41188.1 - 9.2e-08 32.6 0.0 0.024 15.3 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK41188.1 - 1.4e-07 31.7 0.0 1.3 10.1 0.0 5.1 2 1 4 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKK41188.1 - 2.9e-05 24.4 0.0 0.17 12.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KKK41188.1 - 4.5e-05 23.5 0.0 0.37 11.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKK41188.1 - 0.013 15.3 0.0 11 6.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKK41188.1 - 0.02 14.9 0.1 1 9.5 0.0 3.1 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat LRR_9 PF14580.6 KKK41188.1 - 0.083 12.4 3.9 0.46 10.0 0.3 2.3 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KKK41188.1 - 0.31 11.2 0.0 0.31 11.2 0.0 6.4 8 0 0 8 8 7 0 Leucine Rich repeat LRR_1 PF00560.33 KKK41188.1 - 0.41 11.4 19.7 0.38 11.5 0.2 6.1 6 0 0 6 6 5 0 Leucine Rich Repeat Lactamase_B PF00753.27 KKK41189.1 - 4.2e-22 79.1 0.0 7.5e-22 78.3 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK41189.1 - 6.6e-08 32.3 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RHS PF03527.14 KKK41189.1 - 0.026 14.2 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 RHS protein Lactamase_B_6 PF16661.5 KKK41189.1 - 0.13 11.7 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PAP2 PF01569.21 KKK41190.1 - 1.2e-17 64.0 4.2 1.2e-17 64.0 4.2 2.5 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 KKK41190.1 - 2.5e-05 24.1 3.7 2.5e-05 24.1 3.7 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KKK41190.1 - 0.0067 16.9 1.2 0.0067 16.9 1.2 2.8 4 0 0 4 4 4 1 PAP2 superfamily C-terminal DUF1418 PF07214.12 KKK41190.1 - 0.1 12.5 0.8 0.35 10.8 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DUF3040 PF11239.8 KKK41190.1 - 0.55 10.5 8.3 3.6 7.9 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Peptidase_M56 PF05569.11 KKK41190.1 - 0.8 8.8 5.3 2.6 7.1 0.3 3.0 3 0 0 3 3 3 0 BlaR1 peptidase M56 SNARE_assoc PF09335.11 KKK41191.1 - 4.2e-28 98.2 3.4 4.2e-28 98.2 3.4 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein Orf78 PF06024.12 KKK41191.1 - 0.9 9.9 17.9 0.086 13.2 1.4 2.7 3 0 0 3 3 3 0 Orf78 (ac78) TMEM154 PF15102.6 KKK41191.1 - 1.9 8.4 7.0 0.63 9.9 0.6 2.3 2 0 0 2 2 2 0 TMEM154 protein family DUF4577 PF15145.6 KKK41191.1 - 2.1 8.4 4.9 15 5.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Tmemb_9 PF05434.11 KKK41191.1 - 3.8 7.4 7.9 0.33 10.8 1.1 2.2 2 0 0 2 2 2 0 TMEM9 Phage_min_cap2 PF06152.11 KKK41193.1 - 0.071 12.0 0.1 0.071 12.0 0.1 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Pox_J1 PF03338.15 KKK41194.1 - 0.011 15.6 0.5 0.011 15.6 0.5 1.9 2 0 0 2 2 2 0 Poxvirus J1 protein UPF0154 PF03672.13 KKK41195.1 - 0.57 10.2 2.9 1.2 9.2 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Arf PF00025.21 KKK41196.1 - 1.6e-12 47.2 3.0 1.3e-11 44.3 3.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK41196.1 - 1.9e-06 28.1 0.7 4.6e-06 26.8 0.7 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KKK41196.1 - 2.5e-06 27.4 0.8 0.017 14.9 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KKK41196.1 - 6.1e-06 25.6 10.3 0.0015 17.7 5.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KKK41196.1 - 2.2e-05 24.0 2.4 5.4e-05 22.7 2.4 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KKK41196.1 - 3.1e-05 23.6 3.1 0.00011 21.9 3.1 1.8 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KKK41196.1 - 0.0011 19.1 0.4 0.002 18.2 0.3 1.5 2 0 0 2 2 1 1 50S ribosome-binding GTPase MeaB PF03308.16 KKK41196.1 - 0.0013 17.7 0.0 0.29 10.1 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KKK41196.1 - 0.0068 16.7 0.1 0.016 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKK41196.1 - 0.0093 15.7 1.7 0.082 12.6 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK41196.1 - 0.015 15.7 0.1 0.024 15.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KKK41196.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KKK41196.1 - 0.022 14.6 2.1 0.034 13.9 2.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KKK41196.1 - 0.03 13.9 1.8 0.098 12.2 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KKK41196.1 - 0.039 14.5 0.7 0.078 13.5 0.7 1.7 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 KKK41196.1 - 0.045 12.9 0.1 0.092 11.9 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 KKK41196.1 - 0.059 13.3 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KKK41196.1 - 0.1 12.5 5.4 0.5 10.3 5.4 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KKK41196.1 - 0.15 11.1 0.2 0.27 10.3 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KKK41196.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KKK41196.1 - 0.66 10.4 6.3 1.4 9.4 6.3 1.5 1 1 0 1 1 1 0 AAA domain Metallophos_2 PF12850.7 KKK41199.1 - 1.4e-08 35.1 0.0 1.8e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lipase_3 PF01764.25 KKK41199.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Musclin PF11037.8 KKK41201.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle EBV-NA3 PF05009.12 KKK41201.1 - 0.081 12.4 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SplA PF11132.8 KKK41203.1 - 0.14 11.9 0.7 9.1 6.1 0.4 2.4 2 0 0 2 2 2 0 Transcriptional regulator protein (SplA) Actin PF00022.19 KKK41204.1 - 6.5e-134 446.6 0.0 1.7e-133 445.2 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKK41204.1 - 2.9e-06 26.3 0.0 3.6e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein LRR_4 PF12799.7 KKK41205.1 - 3.8e-33 113.0 87.4 9.9e-08 32.2 4.4 8.5 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK41205.1 - 2.3e-25 88.1 73.3 7.3e-07 28.9 8.0 7.5 3 1 6 9 9 9 8 Leucine rich repeat LRR_9 PF14580.6 KKK41205.1 - 6.6e-20 71.3 37.7 2.1e-09 37.1 6.9 4.3 1 1 3 4 4 4 4 Leucine-rich repeat HEAT_2 PF13646.6 KKK41205.1 - 0.0003 21.1 0.0 0.0049 17.2 0.0 2.4 1 1 1 2 2 2 1 HEAT repeats Acetyltransf_1 PF00583.25 KKK41206.1 - 5.6e-13 49.2 0.0 7.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK41206.1 - 2.6e-10 40.3 0.0 3.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK41206.1 - 3.2e-09 37.1 0.0 5.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK41206.1 - 1.1e-08 35.9 0.0 1.3e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK41206.1 - 3.4e-07 30.5 0.3 5.4e-07 29.9 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK41206.1 - 3.7e-05 23.6 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KKK41206.1 - 0.017 14.6 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KKK41206.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Hexapep PF00132.24 KKK41208.1 - 5.2e-06 26.0 15.6 0.0036 17.0 4.1 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK41208.1 - 0.0023 17.6 9.5 0.16 11.7 2.4 3.5 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase PEPcase_2 PF14010.6 KKK41209.1 - 4e-37 127.9 0.0 4.7e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase SUR7 PF06687.12 KKK41209.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 SUR7/PalI family Peptidase_M20 PF01546.28 KKK41212.1 - 0.00016 21.5 0.1 0.00035 20.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK41212.1 - 0.00025 20.9 0.0 0.00047 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Ribosomal_L17 PF01196.19 KKK41212.1 - 0.097 13.6 0.0 0.19 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L17 ECH_1 PF00378.20 KKK41213.1 - 6.4e-45 153.4 0.0 7.1e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK41213.1 - 5e-20 72.3 0.0 1.2e-19 71.1 0.0 1.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase ECF_trnsprt PF12822.7 KKK41214.1 - 2.6e-08 34.2 29.2 3.5e-08 33.7 29.2 1.0 1 0 0 1 1 1 1 ECF transporter, substrate-specific component Phage_holin_3_6 PF07332.11 KKK41214.1 - 2.7 8.1 11.6 0.4 10.7 0.1 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III RFC1 PF08519.12 KKK41215.1 - 0.0028 17.8 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain Ras PF00071.22 KKK41219.1 - 1.8e-46 157.7 0.1 2.1e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK41219.1 - 1.3e-28 99.6 0.0 1.8e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41219.1 - 1.3e-15 57.3 0.1 1.5e-15 57.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK41219.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK41219.1 - 5.7e-05 22.6 0.1 6.5e-05 22.4 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK41219.1 - 0.00016 21.3 0.1 0.14 11.7 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KKK41219.1 - 0.0019 18.0 0.1 0.053 13.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKK41219.1 - 0.0033 17.5 0.0 0.0053 16.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_S2 PF00318.20 KKK41219.1 - 0.05 12.8 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 PduV-EutP PF10662.9 KKK41219.1 - 0.058 13.1 0.2 0.43 10.3 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KKK41219.1 - 0.059 13.3 0.3 0.12 12.3 0.3 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK41219.1 - 0.059 13.7 0.0 0.14 12.4 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK41219.1 - 0.082 13.0 0.1 0.2 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 KKK41219.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 KKK41219.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MobB PF03205.14 KKK41219.1 - 0.088 12.7 0.3 0.18 11.7 0.1 1.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KKK41219.1 - 0.091 13.1 0.0 0.15 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KKK41219.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK41219.1 - 0.094 12.6 0.0 0.74 9.7 0.0 2.0 2 0 0 2 2 2 0 NTPase AFOR_C PF01314.18 KKK41220.1 - 3.3e-25 88.9 0.0 3.6e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 HGD-D PF06050.13 KKK41224.1 - 2.7e-25 89.8 0.0 3.4e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component PI-TkoII_IV PF18714.1 KKK41224.1 - 0.054 13.0 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV HGD-D PF06050.13 KKK41225.1 - 1.1e-60 206.1 0.0 1.2e-60 206.0 0.0 1.0 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component TLP1_add_C PF18313.1 KKK41226.1 - 6.9e-08 32.3 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_C PF02803.18 KKK41226.1 - 0.0002 21.0 0.0 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF5596 PF18082.1 KKK41226.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) Thiolase_N PF00108.23 KKK41227.1 - 2.6e-08 33.6 0.0 6.6e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK41227.1 - 0.0039 16.8 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain GHMP_kinases_C PF08544.13 KKK41227.1 - 0.15 12.5 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal Thiolase_C PF02803.18 KKK41228.1 - 0.001 18.7 3.5 0.0023 17.6 3.5 1.6 1 1 1 2 2 2 1 Thiolase, C-terminal domain Peptidase_M20 PF01546.28 KKK41228.1 - 0.025 14.3 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 OB_aCoA_assoc PF01796.17 KKK41229.1 - 1.8e-07 31.0 0.0 2.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 KKK41229.1 - 0.0023 17.8 0.1 0.0036 17.1 0.1 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) SCP2 PF02036.17 KKK41230.1 - 0.023 15.2 0.0 0.033 14.7 0.0 1.4 1 1 0 1 1 1 0 SCP-2 sterol transfer family Mtd_N PF18454.1 KKK41230.1 - 0.04 13.9 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain ABC_membrane PF00664.23 KKK41231.1 - 1.8e-38 132.8 17.7 2.5e-38 132.3 17.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK41231.1 - 2.4e-33 115.5 0.1 4.1e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KKK41231.1 - 0.00053 20.4 0.2 0.0014 19.1 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KKK41231.1 - 0.0022 17.3 0.0 0.0046 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 KKK41231.1 - 0.0063 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KKK41231.1 - 0.0068 15.9 1.8 0.055 12.9 0.9 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KKK41231.1 - 0.0069 16.8 0.0 0.075 13.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KKK41231.1 - 0.015 15.8 0.0 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KKK41231.1 - 0.017 15.2 0.5 0.077 13.1 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 KKK41231.1 - 0.03 14.6 0.3 0.25 11.6 0.3 2.3 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KKK41231.1 - 0.034 13.9 0.4 1.1 9.0 0.4 2.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase SRP54 PF00448.22 KKK41231.1 - 0.043 13.4 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 KKK41231.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KKK41231.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 KKK41231.1 - 0.085 12.7 1.1 2.3 8.0 0.1 2.9 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK41231.1 - 0.098 12.4 0.1 0.29 10.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KKK41231.1 - 0.14 11.9 0.4 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KKK41231.1 - 0.15 11.8 0.4 0.77 9.5 0.4 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKK41232.1 - 2.6e-37 128.4 0.0 4.5e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKK41232.1 - 7.5e-34 117.6 17.0 1.1e-33 117.1 17.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KKK41232.1 - 4.3e-05 23.0 0.4 0.0018 17.7 0.2 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 KKK41232.1 - 0.00098 18.4 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 KKK41232.1 - 0.002 18.4 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK41232.1 - 0.0028 17.4 0.1 0.07 12.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein NB-ARC PF00931.22 KKK41232.1 - 0.0041 16.3 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_21 PF13304.6 KKK41232.1 - 0.0064 16.3 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KKK41232.1 - 0.0068 16.9 0.3 0.017 15.7 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KKK41232.1 - 0.012 16.1 2.6 0.089 13.2 2.6 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK41232.1 - 0.016 15.2 0.1 0.06 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KKK41232.1 - 0.021 15.3 0.3 0.05 14.1 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK41232.1 - 0.024 14.9 0.4 0.19 11.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKK41232.1 - 0.027 14.2 0.1 0.057 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK41232.1 - 0.029 14.7 0.1 0.071 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KKK41232.1 - 0.037 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KKK41232.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 KKK41232.1 - 0.041 13.6 0.0 0.091 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KKK41232.1 - 0.043 13.6 0.1 0.093 12.5 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KKK41232.1 - 0.043 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 KKK41232.1 - 0.049 13.7 0.1 0.095 12.8 0.1 1.6 1 1 0 1 1 1 0 Helicase HerA, central domain Rad17 PF03215.15 KKK41232.1 - 0.051 13.5 0.0 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KKK41232.1 - 0.055 13.4 0.0 0.26 11.2 0.0 2.1 3 0 0 3 3 1 0 RsgA GTPase AAA_33 PF13671.6 KKK41232.1 - 0.06 13.5 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK41232.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK41232.1 - 0.079 12.3 0.2 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KKK41232.1 - 0.094 12.7 0.1 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KKK41232.1 - 0.11 13.0 0.0 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KKK41232.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 NACHT domain BROMI PF14961.6 KKK41233.1 - 0.022 12.2 0.0 0.026 12.0 0.0 1.0 1 0 0 1 1 1 0 Broad-minded protein Arginosuc_synth PF00764.19 KKK41234.1 - 8.8e-153 509.2 0.0 1.1e-152 508.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KKK41234.1 - 0.00094 18.7 0.0 0.0027 17.2 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 KKK41234.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Semialdhyde_dh PF01118.24 KKK41235.1 - 4e-30 104.7 0.0 7e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 KKK41235.1 - 1.3e-23 84.0 0.0 2.1e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GFO_IDH_MocA PF01408.22 KKK41235.1 - 0.0022 18.8 0.0 0.0044 17.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 KKK41235.1 - 0.0045 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 KKK41235.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Aminotran_3 PF00202.21 KKK41236.1 - 1.1e-119 399.7 0.0 1.3e-119 399.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKK41236.1 - 2.6e-05 23.6 0.0 7.4e-05 22.1 0.0 1.6 1 1 1 2 2 2 1 Aminotransferase class I and II Prefoldin_2 PF01920.20 KKK41236.1 - 0.029 14.3 0.1 0.12 12.4 0.2 1.9 2 0 0 2 2 2 0 Prefoldin subunit Serine_rich PF08824.10 KKK41236.1 - 0.099 12.6 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain Cep57_MT_bd PF06657.13 KKK41236.1 - 0.16 12.5 0.3 0.3 11.6 0.3 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 KKK41236.1 - 0.17 11.9 0.5 0.36 10.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AA_kinase PF00696.28 KKK41237.1 - 3.6e-49 167.5 3.3 4.4e-49 167.3 3.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family HLH PF00010.26 KKK41237.1 - 0.053 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain ArgJ PF01960.18 KKK41238.1 - 1.8e-126 421.9 2.9 2e-126 421.7 2.9 1.0 1 0 0 1 1 1 1 ArgJ family ParBc PF02195.18 KKK41241.1 - 0.0001 22.5 0.1 0.00038 20.7 0.0 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain MULE PF10551.9 KKK41246.1 - 5.2e-06 26.8 0.0 1.1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 KKK41246.1 - 2.6e-05 24.1 1.0 0.00029 20.6 1.0 2.2 1 1 0 1 1 1 1 Transposase Transposase_mut PF00872.18 KKK41246.1 - 0.017 14.0 0.0 0.036 12.9 0.0 1.6 1 0 0 1 1 1 0 Transposase, Mutator family DDE_Tnp_IS66 PF03050.14 KKK41246.1 - 0.019 14.5 0.1 26 4.2 0.0 3.0 3 0 0 3 3 3 0 Transposase IS66 family DUF5595 PF18077.1 KKK41246.1 - 0.72 10.0 4.2 3.4 7.8 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) Thoc2 PF11732.8 KKK41247.1 - 0.067 13.3 0.0 0.77 9.9 0.0 2.7 2 0 0 2 2 2 0 Transcription- and export-related complex subunit DUF3510 PF12022.8 KKK41247.1 - 0.23 11.8 7.0 0.55 10.6 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3510) FliT PF05400.13 KKK41247.1 - 3.9 8.4 5.1 26 5.7 0.4 3.4 3 0 0 3 3 3 0 Flagellar protein FliT Spc7 PF08317.11 KKK41248.1 - 5.2e-05 22.3 21.5 6.5e-05 22.0 21.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 KKK41248.1 - 0.00023 21.5 19.5 0.00051 20.3 10.7 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 KKK41248.1 - 0.00033 21.2 11.5 0.0025 18.4 5.2 2.7 1 1 2 3 3 3 2 SlyX AAA_13 PF13166.6 KKK41248.1 - 0.00061 18.6 15.4 0.00076 18.3 15.4 1.1 1 0 0 1 1 1 1 AAA domain DUF3552 PF12072.8 KKK41248.1 - 0.00082 18.8 15.0 0.00082 18.8 15.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) DUF4407 PF14362.6 KKK41248.1 - 0.00089 18.7 10.7 0.0011 18.5 10.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Prominin PF05478.11 KKK41248.1 - 0.0015 16.6 4.8 0.0015 16.6 4.8 1.1 1 0 0 1 1 1 1 Prominin HIP1_clath_bdg PF16515.5 KKK41248.1 - 0.002 18.7 18.8 0.01 16.4 11.3 2.1 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 KKK41248.1 - 0.0021 17.2 15.1 0.0028 16.8 15.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 KKK41248.1 - 0.0054 16.3 7.8 0.0069 16.0 7.8 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF2884 PF11101.8 KKK41248.1 - 0.0064 16.0 5.8 0.012 15.2 5.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Histidinol_dh PF00815.20 KKK41248.1 - 0.0084 15.2 6.0 0.01 14.8 6.0 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase TPR_MLP1_2 PF07926.12 KKK41248.1 - 0.0089 16.1 20.6 0.33 11.0 10.9 2.1 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein DUF4479 PF14794.6 KKK41248.1 - 0.011 15.6 1.1 0.011 15.6 1.1 3.2 3 1 1 4 4 2 0 Domain of unknown function (DUF4479) HrpB7 PF09486.10 KKK41248.1 - 0.011 16.1 1.8 0.018 15.4 1.4 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF948 PF06103.11 KKK41248.1 - 0.016 15.5 6.9 0.6 10.4 1.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FliJ PF02050.16 KKK41248.1 - 0.018 15.2 11.2 0.025 14.8 9.1 1.9 1 1 1 2 2 2 0 Flagellar FliJ protein APG17 PF04108.12 KKK41248.1 - 0.021 13.9 11.6 0.026 13.7 11.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 DASH_Duo1 PF08651.10 KKK41248.1 - 0.022 14.5 13.2 0.062 13.1 4.2 2.8 1 1 0 2 2 2 0 DASH complex subunit Duo1 LUC7 PF03194.15 KKK41248.1 - 0.026 14.2 10.0 0.032 13.9 10.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus KASH_CCD PF14662.6 KKK41248.1 - 0.029 14.2 21.9 0.19 11.5 21.9 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TACC_C PF05010.14 KKK41248.1 - 0.03 14.1 17.1 0.04 13.7 17.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MCPsignal PF00015.21 KKK41248.1 - 0.032 14.0 6.2 0.047 13.5 6.2 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TolA_bind_tri PF16331.5 KKK41248.1 - 0.039 14.0 14.1 0.41 10.8 9.2 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation ISG65-75 PF11727.8 KKK41248.1 - 0.041 13.1 11.9 0.071 12.3 10.0 1.8 1 1 1 2 2 2 0 Invariant surface glycoprotein zinc_ribbon_4 PF13717.6 KKK41248.1 - 0.047 13.6 0.7 10 6.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain PKcGMP_CC PF16808.5 KKK41248.1 - 0.06 13.2 0.8 0.06 13.2 0.8 4.6 2 2 3 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Zn-ribbon_8 PF09723.10 KKK41248.1 - 0.063 13.4 1.1 4 7.6 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain HMMR_N PF15905.5 KKK41248.1 - 0.069 12.6 25.4 0.096 12.1 25.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4795 PF16043.5 KKK41248.1 - 0.073 12.7 18.1 0.1 12.2 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) zf-ribbon_3 PF13248.6 KKK41248.1 - 0.077 12.4 6.1 0.69 9.4 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain PHM7_cyt PF14703.6 KKK41248.1 - 0.098 12.9 11.5 0.22 11.7 11.4 1.6 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter TF_Zn_Ribbon PF08271.12 KKK41248.1 - 0.1 12.1 1.3 6.6 6.3 0.1 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding V_ATPase_I PF01496.19 KKK41248.1 - 0.11 10.4 9.4 0.15 9.9 9.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.6 KKK41248.1 - 0.12 11.7 17.8 0.17 11.3 16.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) FPP PF05911.11 KKK41248.1 - 0.16 10.1 20.3 0.19 9.9 20.3 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil RPW8 PF05659.11 KKK41248.1 - 0.18 11.5 13.2 0.66 9.7 4.4 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF5082 PF16888.5 KKK41248.1 - 0.18 12.1 19.3 1.6 9.1 10.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) LPP PF04728.13 KKK41248.1 - 0.18 12.2 6.8 3.4 8.1 0.3 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF16 PF01519.16 KKK41248.1 - 0.19 12.2 21.6 16 6.0 21.6 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 CEP63 PF17045.5 KKK41248.1 - 0.19 11.6 18.1 0.064 13.2 13.0 1.9 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa DUF1894 PF08979.11 KKK41248.1 - 0.2 12.1 5.7 0.34 11.3 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1894) Spectrin PF00435.21 KKK41248.1 - 0.2 12.2 15.5 0.84 10.2 15.2 2.0 1 1 1 2 2 2 0 Spectrin repeat BLOC1_2 PF10046.9 KKK41248.1 - 0.2 12.0 21.8 0.069 13.4 10.7 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 KKK41248.1 - 0.22 11.3 16.8 0.76 9.6 7.4 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 ADIP PF11559.8 KKK41248.1 - 0.23 11.5 19.4 2 8.5 7.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding USP8_interact PF08941.10 KKK41248.1 - 0.26 11.1 8.9 0.16 11.8 3.8 2.1 1 1 1 2 2 2 0 USP8 interacting UPF0242 PF06785.11 KKK41248.1 - 0.29 11.2 26.1 0.51 10.4 26.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF148 PF02520.17 KKK41248.1 - 0.29 11.3 20.0 2.9 8.0 19.1 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 RecQ_Zn_bind PF16124.5 KKK41248.1 - 0.31 11.8 5.8 6.8 7.5 0.0 2.8 2 1 0 2 2 2 0 RecQ zinc-binding DUF4200 PF13863.6 KKK41248.1 - 0.32 11.4 26.3 3.9 7.9 6.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) PRKG1_interact PF15898.5 KKK41248.1 - 0.33 11.9 18.2 21 6.1 18.2 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain zinc_ribbon_2 PF13240.6 KKK41248.1 - 0.33 10.7 8.8 0.92 9.3 0.7 2.8 2 0 0 2 2 2 0 zinc-ribbon domain FliD_C PF07195.12 KKK41248.1 - 0.33 10.3 16.3 0.43 10.0 3.5 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Fez1 PF06818.15 KKK41248.1 - 0.35 11.3 18.1 0.17 12.3 14.4 1.9 1 1 1 2 2 2 0 Fez1 LppA PF16708.5 KKK41248.1 - 0.38 10.7 2.8 7.6 6.4 2.8 2.3 1 1 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium DUF3130 PF11328.8 KKK41248.1 - 0.44 10.8 6.0 0.82 10.0 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3130 COG5 PF10392.9 KKK41248.1 - 0.45 10.7 10.0 2.3 8.4 1.5 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 MutS_III PF05192.18 KKK41248.1 - 0.47 10.6 4.1 0.53 10.5 4.1 1.1 1 0 0 1 1 1 0 MutS domain III DUF3584 PF12128.8 KKK41248.1 - 0.49 7.8 15.3 0.61 7.5 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_GPO PF05929.11 KKK41248.1 - 0.55 9.8 8.0 0.72 9.4 8.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1796 PF08795.10 KKK41248.1 - 0.57 10.1 2.8 0.84 9.6 2.8 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) DUF4435 PF14491.6 KKK41248.1 - 0.59 10.0 13.9 0.87 9.4 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) Sulfatase_C PF14707.6 KKK41248.1 - 0.63 10.8 3.2 3.8 8.3 1.5 2.2 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase MerR-DNA-bind PF09278.11 KKK41248.1 - 0.69 10.5 5.0 5.6 7.6 1.2 2.9 1 1 2 3 3 3 0 MerR, DNA binding DUF3450 PF11932.8 KKK41248.1 - 0.72 9.1 18.2 0.34 10.2 14.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PspA_IM30 PF04012.12 KKK41248.1 - 0.76 9.3 14.1 1.4 8.4 10.0 2.1 1 1 1 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.8 KKK41248.1 - 0.8 9.8 35.4 0.85 9.7 16.8 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding YscO-like PF16789.5 KKK41248.1 - 0.8 9.7 17.6 1.5 8.9 17.6 1.4 1 0 0 1 1 1 0 YscO-like protein HOOK PF05622.12 KKK41248.1 - 0.82 7.7 21.9 0.99 7.5 21.9 1.1 1 0 0 1 1 1 0 HOOK protein Vps54_N PF10475.9 KKK41248.1 - 0.82 8.9 12.5 4.7 6.4 0.2 2.1 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex CC2-LZ PF16516.5 KKK41248.1 - 0.88 10.0 21.4 0.45 10.9 11.9 2.5 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF812 PF05667.11 KKK41248.1 - 0.96 8.2 26.1 4.1 6.2 26.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 KKK41248.1 - 1.1 9.3 15.7 4.7 7.3 13.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KKK41248.1 - 1.1 9.2 14.7 20 5.2 14.7 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMEM237 PF15383.6 KKK41248.1 - 1.2 8.2 5.4 1.5 7.9 5.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 HemX PF04375.14 KKK41248.1 - 1.3 8.3 15.3 8.5 5.6 15.3 1.9 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3090 PF11290.8 KKK41248.1 - 1.3 8.8 5.1 8 6.2 5.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3090) MAD PF05557.13 KKK41248.1 - 1.3 7.3 21.1 1.6 7.0 21.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Hemagglutinin PF00509.18 KKK41248.1 - 1.4 7.2 11.5 0.11 10.9 3.9 2.0 1 1 1 2 2 2 0 Haemagglutinin Dna2 PF08696.11 KKK41248.1 - 1.4 8.6 10.3 0.65 9.8 6.3 1.9 1 1 1 2 2 2 0 DNA replication factor Dna2 RNase_HII PF01351.18 KKK41248.1 - 1.7 8.5 7.5 2 8.2 7.2 1.3 1 1 0 1 1 1 0 Ribonuclease HII Prefoldin_2 PF01920.20 KKK41248.1 - 1.7 8.6 26.9 0.86 9.6 12.2 3.0 1 1 2 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.10 KKK41248.1 - 1.8 8.7 19.4 2.1 8.5 8.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Dad1 PF08649.10 KKK41248.1 - 2.1 8.6 11.1 8.3 6.7 4.1 2.7 1 1 1 2 2 2 0 DASH complex subunit Dad1 VPS38 PF17649.1 KKK41248.1 - 2.4 7.0 15.3 3.6 6.3 15.3 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 38 NPV_P10 PF05531.12 KKK41248.1 - 2.4 8.7 16.3 5.6 7.5 7.9 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 KKK41248.1 - 2.8 7.1 15.2 1.6 7.9 12.2 1.6 1 1 0 1 1 1 0 TMPIT-like protein Phage_HK97_TLTM PF06120.11 KKK41248.1 - 3.4 6.8 19.5 0.45 9.6 9.2 2.1 1 1 1 2 2 2 0 Tail length tape measure protein Syntaxin-6_N PF09177.11 KKK41248.1 - 3.6 8.2 16.3 80 3.9 16.3 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Bacillus_HBL PF05791.11 KKK41248.1 - 3.8 7.3 18.6 8.5 6.2 6.2 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Telomere_reg-2 PF10193.9 KKK41248.1 - 4.3 7.8 6.0 1.1 9.7 1.5 1.9 1 1 1 2 2 2 0 Telomere length regulation protein Nup88 PF10168.9 KKK41248.1 - 4.3 5.0 14.7 5.6 4.6 14.7 1.2 1 0 0 1 1 1 0 Nuclear pore component YvrJ PF12841.7 KKK41248.1 - 4.4 6.9 6.5 8.2 6.0 0.1 3.4 1 1 1 2 2 2 0 YvrJ protein family Glutaredoxin2_C PF04399.13 KKK41248.1 - 4.5 7.1 10.3 6.7 6.6 3.6 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain 5_nucleotid PF05761.14 KKK41248.1 - 4.8 6.0 8.7 5.8 5.7 8.7 1.2 1 0 0 1 1 1 0 5' nucleotidase family TFIIS_C PF01096.18 KKK41248.1 - 5 7.1 6.3 18 5.3 1.6 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) IFT57 PF10498.9 KKK41248.1 - 5.2 5.9 20.6 7 5.5 20.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 KKK41248.1 - 5.3 6.4 21.5 20 4.5 20.5 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 Fzo_mitofusin PF04799.13 KKK41248.1 - 5.7 6.5 11.2 2.2e+02 1.3 11.2 2.2 1 1 0 1 1 1 0 fzo-like conserved region YkyA PF10368.9 KKK41248.1 - 5.8 6.5 30.8 3.8 7.2 19.2 2.0 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein COG2 PF06148.11 KKK41248.1 - 7.7 6.6 12.7 24 5.0 12.7 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF745 PF05335.13 KKK41248.1 - 8.1 6.1 10.5 18 5.0 9.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1759 PF03564.15 KKK41248.1 - 8.4 6.3 10.9 3.8 7.5 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Med9 PF07544.13 KKK41248.1 - 8.5 6.5 24.8 13 5.9 1.9 3.6 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CENP-Q PF13094.6 KKK41248.1 - 9.6 6.4 18.6 7.7 6.7 9.5 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RelB_N PF18506.1 KKK41250.1 - 0.31 10.9 4.2 0.55 10.1 4.2 1.4 1 1 0 1 1 1 0 RelB Antitoxin alpha helical domain LRR_8 PF13855.6 KKK41251.1 - 4e-24 84.1 73.2 5.1e-10 39.0 9.9 5.0 2 1 4 7 7 7 6 Leucine rich repeat SIR2_2 PF13289.6 KKK41251.1 - 2e-14 53.9 0.5 4.9e-14 52.7 0.5 1.6 1 0 0 1 1 1 1 SIR2-like domain LRR_4 PF12799.7 KKK41251.1 - 1.3e-12 47.7 59.4 1.2e-05 25.6 8.0 6.1 3 1 3 7 7 7 5 Leucine Rich repeats (2 copies) RsmF_methylt_CI PF17126.5 KKK41251.1 - 0.0011 18.9 0.5 21 5.3 0.0 5.1 2 1 4 6 6 6 1 RsmF rRNA methyltransferase first C-terminal domain LRR_1 PF00560.33 KKK41251.1 - 0.76 10.6 28.3 27 5.9 2.0 8.2 6 2 0 6 6 6 0 Leucine Rich Repeat Pyr_redox_dim PF02852.22 KKK41254.1 - 3.2e-11 43.5 0.0 3.7e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Cnl2_NKP2 PF09447.10 KKK41254.1 - 0.13 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Cnl2/NKP2 family protein CoA_binding PF02629.19 KKK41255.1 - 3.6e-23 82.1 1.2 3.6e-23 82.1 1.2 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KKK41255.1 - 7e-13 48.7 0.6 1.1e-12 48.1 0.6 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KKK41255.1 - 1.1e-09 38.2 0.2 1.6e-09 37.7 0.2 1.2 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain TatD_DNase PF01026.21 KKK41255.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase CoA_binding_2 PF13380.6 KKK41255.1 - 0.051 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain ATP-grasp_2 PF08442.10 KKK41256.1 - 7.3e-44 149.7 1.7 7.3e-44 149.7 1.7 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KKK41256.1 - 5.2e-13 49.1 0.1 9.9e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase GARS_A PF01071.19 KKK41256.1 - 0.012 15.4 1.8 0.018 14.8 0.4 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 KKK41256.1 - 0.013 15.0 0.2 0.019 14.5 0.2 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 KKK41256.1 - 0.015 14.8 0.4 0.029 13.9 0.4 1.5 1 0 0 1 1 1 0 ATP-grasp domain MFS_2 PF13347.6 KKK41257.1 - 3.4e-36 124.7 41.0 4e-36 124.5 41.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KKK41257.1 - 9.1e-09 34.7 44.3 1.4e-06 27.5 14.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Nitroreductase PF00881.24 KKK41259.1 - 1.3e-26 93.7 0.0 1.8e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK41259.1 - 4.3e-08 33.0 5.2 0.0023 17.5 0.1 3.2 1 1 2 3 3 3 3 Putative TM nitroreductase Fer4_9 PF13187.6 KKK41259.1 - 1.5e-05 25.1 10.9 2.4e-05 24.4 10.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK41259.1 - 4.8e-05 23.9 4.7 0.058 14.0 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK41259.1 - 0.0003 21.7 6.9 0.092 13.7 0.6 2.4 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK41259.1 - 0.001 19.1 11.2 0.0018 18.4 11.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41259.1 - 0.0016 18.1 15.6 0.01 15.6 3.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK41259.1 - 0.0024 18.0 10.3 0.0047 17.0 10.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41259.1 - 0.0075 16.3 13.6 0.33 11.1 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 KKK41259.1 - 0.014 16.1 7.1 5 7.9 7.1 2.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain CxC7 PF18866.1 KKK41259.1 - 0.93 9.7 5.5 2 8.6 5.5 1.5 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases Fer4_2 PF12797.7 KKK41259.1 - 1.2 9.3 11.9 0.12 12.5 2.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 KKK41259.1 - 7.8 7.0 15.2 1.8e+02 2.6 15.2 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Beta-Casp PF10996.8 KKK41266.1 - 9.9e-24 83.8 0.0 3.2e-23 82.1 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain KH_7 PF17214.3 KKK41266.1 - 2.9e-16 59.2 1.9 2.9e-15 56.0 0.6 2.6 1 1 1 2 2 2 1 KH domain Lactamase_B_6 PF16661.5 KKK41266.1 - 1.7e-15 56.9 0.0 3.9e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KKK41266.1 - 1.6e-12 47.2 0.0 3.9e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KKK41266.1 - 1.5e-10 41.0 0.0 1.8e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK41266.1 - 2.1e-10 41.0 0.0 2.3e-07 31.0 0.0 2.7 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily KH_2 PF07650.17 KKK41266.1 - 6.1e-07 29.2 0.7 2.4e-06 27.3 0.7 2.1 1 0 0 1 1 1 1 KH domain Lactamase_B_3 PF13483.6 KKK41266.1 - 0.00012 22.0 0.1 0.00055 19.9 0.0 2.1 3 0 0 3 3 3 1 Beta-lactamase superfamily domain KH_1 PF00013.29 KKK41266.1 - 0.0096 15.7 0.4 0.025 14.4 0.4 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KKK41266.1 - 0.08 12.8 1.5 0.16 11.9 0.3 2.1 2 0 0 2 2 2 0 KH domain Ribosomal_L30 PF00327.20 KKK41270.1 - 2e-07 30.8 1.5 3.3e-07 30.1 0.1 2.2 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e zf-SCNM1 PF15803.5 KKK41270.1 - 0.053 13.2 0.5 0.12 12.0 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 Ribosomal_S5_C PF03719.15 KKK41271.1 - 6.9e-23 79.9 0.0 1.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KKK41271.1 - 5.2e-18 64.8 3.4 8.2e-18 64.2 0.7 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_L5e PF17144.4 KKK41272.1 - 1.2e-26 93.6 0.7 2.5e-21 76.4 0.3 2.2 1 1 1 2 2 2 2 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KKK41272.1 - 7.7e-08 33.2 0.4 1.5e-07 32.2 0.4 1.5 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KKK41272.1 - 2.2e-07 31.3 0.1 3e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L19e PF01280.20 KKK41273.1 - 2.6e-52 176.7 13.7 2.9e-52 176.6 13.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e DUF4019 PF13211.6 KKK41273.1 - 0.2 12.1 2.6 0.42 11.0 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4019) Ribosomal_L32e PF01655.18 KKK41274.1 - 2.9e-30 104.8 1.7 3.9e-30 104.4 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 NeuB PF03102.14 KKK41274.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NeuB family SAM_Exu PF18609.1 KKK41274.1 - 0.11 12.6 1.0 0.27 11.4 0.1 2.0 2 0 0 2 2 2 0 Exuperantia SAM-like domain RuvA_C PF07499.13 KKK41274.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 RuvA, C-terminal domain Ribosomal_L6 PF00347.23 KKK41275.1 - 1.2e-19 70.8 1.9 8.2e-11 42.4 2.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF2196 PF09962.9 KKK41275.1 - 0.15 12.1 1.9 10 6.2 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2196) Chordopox_A30L PF06015.12 KKK41275.1 - 0.44 10.4 2.6 0.62 9.9 1.3 1.9 1 1 1 2 2 2 0 Chordopoxvirus A30L protein Ribosomal_S8 PF00410.19 KKK41276.1 - 1.3e-23 83.4 0.1 1.9e-23 82.8 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S14 PF00253.21 KKK41277.1 - 1.2e-07 31.4 7.1 1.3e-07 31.3 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-RRN7 PF11781.8 KKK41277.1 - 1.3 8.8 12.8 1.2 8.9 1.9 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribosomal_L5 PF00281.19 KKK41278.1 - 7.7e-18 64.6 0.1 2.1e-17 63.2 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KKK41278.1 - 3.9e-17 62.2 0.1 8.1e-17 61.2 0.0 1.6 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_S4e PF00900.20 KKK41279.1 - 2e-25 88.5 0.1 3.4e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 KKK41279.1 - 6.1e-10 39.0 1.8 1.1e-09 38.2 1.8 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KKK41279.1 - 2e-07 30.6 0.1 5.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 KKK41279.1 - 0.015 15.2 1.3 0.016 15.1 0.0 1.7 2 0 0 2 2 2 0 KOW motif Ribosomal_L26 PF16906.5 KKK41280.1 - 1.6e-19 70.1 0.2 2.1e-19 69.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KKK41280.1 - 0.00017 21.4 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 KOW motif ProQ_C PF17516.2 KKK41280.1 - 0.076 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 ProQ C-terminal domain Ribosomal_L14 PF00238.19 KKK41281.1 - 2e-31 108.6 0.0 2.4e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e WD40_3 PF15911.5 KKK41281.1 - 0.091 12.8 0.1 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Ribosomal_S17 PF00366.20 KKK41282.1 - 0.0001 22.3 0.1 0.00011 22.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 MG2 PF01835.19 KKK41286.1 - 8.8e-18 64.6 0.2 1.8e-12 47.5 0.0 4.0 3 0 0 3 3 3 2 MG2 domain Big_1 PF02369.16 KKK41286.1 - 1.2e-08 34.9 1.4 0.053 13.5 0.7 5.2 6 0 0 6 6 6 2 Bacterial Ig-like domain (group 1) MG3 PF17791.1 KKK41286.1 - 3.6e-05 23.9 0.3 0.00021 21.5 0.3 2.3 2 0 0 2 2 2 1 Macroglobulin domain MG3 MG4 PF17789.1 KKK41286.1 - 0.00047 20.2 0.0 6.1 7.1 0.0 4.4 4 0 0 4 4 4 2 Macroglobulin domain MG4 Arrestin_C PF02752.22 KKK41286.1 - 0.048 14.1 0.2 3.6 8.0 0.0 3.5 4 0 0 4 4 4 0 Arrestin (or S-antigen), C-terminal domain A2M_BRD PF07703.14 KKK41286.1 - 0.081 13.3 3.0 5 7.5 0.1 3.3 3 1 0 3 3 3 0 Alpha-2-macroglobulin bait region domain Gar1 PF04410.14 KKK41286.1 - 0.14 11.9 0.2 17 5.2 0.0 2.9 3 0 0 3 3 3 0 Gar1/Naf1 RNA binding region HTH_5 PF01022.20 KKK41287.1 - 0.0069 16.2 0.2 0.012 15.5 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 KKK41287.1 - 0.016 15.1 0.2 0.025 14.4 0.2 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 KKK41287.1 - 0.06 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 LexA DNA binding domain Gemini_mov PF01708.16 KKK41287.1 - 0.82 9.5 5.3 0.81 9.5 4.1 1.6 1 1 0 1 1 1 0 Geminivirus putative movement protein PGK PF00162.19 KKK41288.1 - 8.1e-92 308.1 5.0 9.2e-92 307.9 5.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase AIRC PF00731.20 KKK41289.1 - 1.5e-18 66.8 4.4 2.3e-18 66.2 4.4 1.2 1 0 0 1 1 1 1 AIR carboxylase TPR_12 PF13424.6 KKK41290.1 - 5.6e-11 42.6 0.5 0.011 15.9 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat MIT PF04212.18 KKK41290.1 - 1e-06 28.7 2.0 0.018 15.1 0.0 2.6 2 1 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 KKK41290.1 - 0.00014 21.5 0.4 2.4 8.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KKK41290.1 - 0.00054 19.9 0.3 0.56 10.5 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK41290.1 - 0.00064 19.5 0.0 0.079 12.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Trans_coact PF16805.5 KKK41290.1 - 0.0075 16.3 0.2 0.033 14.3 0.1 2.1 2 0 0 2 2 2 1 Phage late-transcription coactivator NOG1_N PF17835.1 KKK41290.1 - 0.015 15.3 2.0 1.1 9.2 0.4 2.2 2 0 0 2 2 2 0 NOG1 N-terminal helical domain TPR_11 PF13414.6 KKK41290.1 - 0.04 13.6 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 KKK41290.1 - 0.072 13.3 4.3 16 6.0 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 KKK41290.1 - 0.12 12.4 2.6 4.3 7.4 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF627) LisH_TPL PF17814.1 KKK41290.1 - 0.12 12.0 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 LisH-like dimerisation domain FRB_dom PF08771.11 KKK41290.1 - 0.23 11.9 4.2 1.3 9.5 1.4 2.6 1 1 0 2 2 2 0 FKBP12-rapamycin binding domain SF3A3 PF16837.5 KKK41290.1 - 2.3 8.8 8.6 2.6 8.6 5.4 2.5 2 1 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DUF111 PF01969.17 KKK41291.1 - 7.3e-96 321.5 0.0 8.3e-96 321.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF111 PhoU_div PF01865.16 KKK41291.1 - 0.045 13.1 0.1 0.045 13.1 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function DUF47 NusB PF01029.18 KKK41291.1 - 0.049 13.9 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 NusB family DUF5636 PF18686.1 KKK41291.1 - 0.13 12.4 1.2 0.23 11.6 1.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5636) DUF362 PF04015.12 KKK41294.1 - 4.5e-10 40.1 0.0 1.3e-09 38.6 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF362) ACT_4 PF13291.6 KKK41295.1 - 0.012 16.2 0.0 0.77 10.4 0.0 2.2 2 0 0 2 2 2 0 ACT domain ACT PF01842.25 KKK41295.1 - 0.092 12.5 0.0 0.71 9.7 0.0 2.1 2 1 0 2 2 2 0 ACT domain Methyltransf_11 PF08241.12 KKK41296.1 - 1.2e-09 38.6 0.0 1.8e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK41296.1 - 3.3e-06 27.0 0.1 5.5e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK41296.1 - 3.6e-06 26.9 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK41296.1 - 0.00059 20.5 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK41296.1 - 0.0039 17.9 0.0 0.0064 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-FPG_IleRS PF06827.14 KKK41297.1 - 0.0085 15.9 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-C4_ClpX PF06689.13 KKK41297.1 - 0.019 14.9 3.2 0.046 13.6 3.2 1.7 1 1 0 1 1 1 0 ClpX C4-type zinc finger Atg14 PF10186.9 KKK41297.1 - 0.044 12.9 8.9 0.052 12.6 8.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C4pol PF14260.6 KKK41297.1 - 0.11 13.0 2.1 0.15 12.6 1.5 1.6 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta CLZ PF16526.5 KKK41297.1 - 0.11 12.8 4.3 0.14 12.5 0.1 2.4 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 KKK41297.1 - 0.13 12.4 10.4 0.1 12.7 7.1 2.2 2 1 0 2 2 2 0 bZIP transcription factor LOH1CR12 PF10158.9 KKK41297.1 - 0.14 12.1 3.3 0.25 11.4 3.3 1.5 1 1 0 1 1 1 0 Tumour suppressor protein Ima1_N PF09779.9 KKK41297.1 - 0.25 12.2 6.0 0.95 10.3 5.8 1.8 1 1 0 1 1 1 0 Ima1 N-terminal domain Mad3_BUB1_I_2 PF17014.5 KKK41297.1 - 0.49 10.5 6.4 1.3 9.2 0.9 2.3 1 1 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein PCRF PF03462.18 KKK41297.1 - 1.2 9.0 6.2 1.5 8.7 6.2 1.1 1 0 0 1 1 1 0 PCRF domain TauE PF01925.19 KKK41298.1 - 3e-39 135.1 28.2 3.6e-39 134.8 28.2 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE FtsH_ext PF06480.15 KKK41298.1 - 1.9 8.9 4.6 4 7.8 3.4 2.2 2 0 0 2 2 2 0 FtsH Extracellular MazE_antitoxin PF04014.18 KKK41300.1 - 9.5e-05 22.2 0.2 0.00032 20.6 0.0 2.0 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin Zn_dep_PLPC PF00882.18 KKK41302.1 - 1.3e-11 44.8 3.4 9.7e-11 42.0 2.6 2.1 1 1 1 2 2 2 2 Zinc dependent phospholipase C YdjM PF04307.14 KKK41302.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase UbiA PF01040.18 KKK41303.1 - 1.1e-11 44.6 6.1 1.7e-11 43.9 6.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2207 PF09972.9 KKK41303.1 - 3.9 6.1 4.8 3.9 6.1 4.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Arf PF00025.21 KKK41308.1 - 1e-18 67.4 0.1 1.6e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK41308.1 - 1.8e-13 50.7 0.2 6.7e-13 48.9 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK41308.1 - 4.9e-13 49.0 0.1 1e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KKK41308.1 - 2.7e-06 27.4 0.1 5.5e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TPR_2 PF07719.17 KKK41308.1 - 0.00037 20.4 0.0 0.00086 19.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK41308.1 - 0.00059 19.5 0.1 0.0016 18.2 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat PduV-EutP PF10662.9 KKK41308.1 - 0.001 18.8 1.4 0.0038 17.0 0.4 2.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 KKK41308.1 - 0.0026 18.3 0.0 0.0059 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KKK41308.1 - 0.0033 18.0 0.9 0.0053 17.3 0.5 1.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KKK41308.1 - 0.0039 17.1 0.3 0.25 11.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 KKK41308.1 - 0.0098 15.3 0.1 0.022 14.1 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region TPR_8 PF13181.6 KKK41308.1 - 0.012 15.8 0.0 0.047 13.9 0.0 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK41308.1 - 0.044 13.5 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 TPR repeat AAA_22 PF13401.6 KKK41308.1 - 0.066 13.5 0.1 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain TPR_10 PF13374.6 KKK41308.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SRP-alpha_N PF04086.13 KKK41308.1 - 0.081 12.8 1.5 0.12 12.3 1.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4844 PF16133.5 KKK41309.1 - 0.11 13.1 0.1 0.12 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) CPBP PF02517.16 KKK41311.1 - 2e-08 34.5 14.8 2e-08 34.5 14.8 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Acetyltransf_1 PF00583.25 KKK41312.1 - 6.9e-10 39.2 0.1 1.8e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK41312.1 - 2.3e-07 30.8 0.1 3.9e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK41312.1 - 2.2e-05 25.2 0.0 4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK41312.1 - 0.0002 21.7 0.1 0.00053 20.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK41312.1 - 0.00033 20.8 0.2 0.0005 20.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cas_Cas1 PF01867.16 KKK41312.1 - 0.047 12.8 0.1 0.072 12.2 0.1 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 zinc_ribbon_2 PF13240.6 KKK41313.1 - 8e-07 28.6 2.8 0.0021 17.7 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 KKK41313.1 - 9.1e-05 22.4 0.9 0.00017 21.5 0.9 1.4 1 1 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK41313.1 - 0.00029 20.1 3.3 0.0065 15.8 0.2 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zf-dskA_traR PF01258.17 KKK41313.1 - 0.0092 15.9 0.3 0.31 11.0 0.0 2.3 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger HNH_5 PF14279.6 KKK41313.1 - 0.014 15.3 0.5 4.5 7.2 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease Nudix_N_2 PF14803.6 KKK41313.1 - 0.06 13.3 1.5 2.6 8.1 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zf-C2H2_11 PF16622.5 KKK41313.1 - 0.11 12.3 2.8 2.1 8.2 0.3 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type BRI3BP PF14965.6 KKK41313.1 - 0.13 11.8 1.4 0.17 11.3 1.4 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 NOB1_Zn_bind PF08772.11 KKK41313.1 - 0.19 11.9 3.5 0.7 10.1 3.5 1.8 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like ROS_MUCR PF05443.11 KKK41313.1 - 0.27 11.3 0.4 2 8.5 0.1 2.0 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein zinc_ribbon_9 PF14369.6 KKK41313.1 - 0.48 10.7 3.3 2 8.8 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon UPF0547 PF10571.9 KKK41313.1 - 1.3 9.2 4.5 4.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Prim_Zn_Ribbon PF08273.12 KKK41313.1 - 3.6 8.0 6.0 35 4.8 5.8 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Succ_CoA_lig PF13607.6 KKK41314.1 - 3.4e-45 153.2 0.0 2.9e-43 147.0 0.0 2.4 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK41314.1 - 1.4e-21 77.2 0.1 3.3e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 KKK41314.1 - 1.3e-08 35.4 0.9 6.6e-08 33.1 0.1 2.6 3 0 0 3 3 3 1 CoA binding domain FAD_binding_4 PF01565.23 KKK41316.1 - 8.2e-17 61.2 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HTH_45 PF14947.6 KKK41320.1 - 1.8e-05 24.6 8.2 0.002 18.1 2.5 3.2 2 1 1 3 3 3 2 Winged helix-turn-helix HTH_24 PF13412.6 KKK41320.1 - 0.0012 18.4 7.8 0.003 17.1 1.5 2.9 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding TBPIP PF07106.13 KKK41320.1 - 0.011 15.7 8.7 0.066 13.2 2.1 3.2 2 1 1 3 3 3 0 TBPIP/Hop2 winged helix domain PIP5K PF01504.18 KKK41320.1 - 0.011 15.0 2.4 0.015 14.5 2.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase HTH_11 PF08279.12 KKK41320.1 - 0.024 14.6 1.3 0.13 12.3 1.5 2.1 2 0 0 2 2 2 0 HTH domain YqbF PF14553.6 KKK41320.1 - 0.053 13.4 1.8 1.4 8.9 0.3 2.8 2 0 0 2 2 2 0 YqbF, hypothetical protein domain HTH_36 PF13730.6 KKK41320.1 - 0.074 13.0 0.3 0.074 13.0 0.3 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KKK41320.1 - 0.09 12.8 0.2 0.56 10.2 0.0 2.3 2 1 1 3 3 3 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KKK41320.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain LapA_dom PF06305.11 KKK41321.1 - 0.0082 15.9 2.4 0.0082 15.9 2.4 4.9 2 2 2 4 4 4 1 Lipopolysaccharide assembly protein A domain adh_short_C2 PF13561.6 KKK41322.1 - 1e-59 201.9 0.2 1.8e-59 201.1 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK41322.1 - 7.9e-55 185.3 0.4 1.3e-54 184.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK41322.1 - 5.2e-05 23.2 0.1 0.0001 22.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK41322.1 - 0.00067 19.2 0.9 0.0059 16.1 0.9 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KKK41322.1 - 0.069 13.1 0.4 0.15 12.1 0.2 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MazG PF03819.17 KKK41322.1 - 0.2 11.8 0.9 2 8.6 0.1 2.4 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Adeno_E3B PF03376.14 KKK41324.1 - 0.13 12.5 0.2 0.29 11.4 0.2 1.5 1 0 0 1 1 1 0 Adenovirus E3B protein NosD PF05048.13 KKK41325.1 - 3.4e-39 134.6 72.1 6.2e-32 110.8 35.9 2.3 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK41325.1 - 2.3e-14 53.6 50.7 8.5e-12 45.2 31.9 2.7 1 1 1 2 2 2 2 Right handed beta helix region YXWGXW PF12779.7 KKK41325.1 - 0.061 13.5 1.4 0.061 13.5 1.4 2.9 3 0 0 3 3 3 0 YXWGXW repeat (2 copies) His_Phos_1 PF00300.22 KKK41326.1 - 6.5e-35 120.6 0.0 7.7e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Porin_6 PF16939.5 KKK41326.1 - 0.057 12.5 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative porin Histone_H2A_C PF16211.5 KKK41326.1 - 0.078 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 C-terminus of histone H2A Suppressor_APC PF11414.8 KKK41328.1 - 0.0008 19.4 1.4 0.0021 18.1 0.5 2.2 2 1 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein RLL PF10036.9 KKK41328.1 - 0.038 13.9 7.3 3.1 7.6 5.6 3.0 1 1 0 2 2 2 0 RNA transcription, translation and transport factor protein Bromodomain PF00439.25 KKK41328.1 - 0.25 11.5 4.7 0.57 10.3 2.3 2.7 1 1 0 2 2 2 0 Bromodomain YtxH PF12732.7 KKK41328.1 - 0.26 11.9 7.3 4.3 7.9 0.2 2.3 2 0 0 2 2 2 0 YtxH-like protein Transglut_core PF01841.19 KKK41331.1 - 1.1e-23 83.9 0.0 2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Peptidase_C93 PF06035.11 KKK41331.1 - 0.0018 18.1 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial transglutaminase-like cysteine proteinase BTLCP DUF553 PF04473.12 KKK41331.1 - 0.0055 16.2 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like domain Transglut_core3 PF13471.6 KKK41331.1 - 0.038 13.9 0.1 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily DUF5385 PF17359.2 KKK41331.1 - 3 7.4 5.8 4.8 6.7 5.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) FeoB_associated PF12669.7 KKK41331.1 - 5 7.6 6.6 8.9 6.8 6.6 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein LAGLIDADG_3 PF14528.6 KKK41333.1 - 0.02 15.2 0.4 3.3 8.1 0.0 4.0 3 0 0 3 3 3 0 LAGLIDADG-like domain zf-ribbon_3 PF13248.6 KKK41333.1 - 0.035 13.5 1.2 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK41333.1 - 0.046 13.5 0.1 0.046 13.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_7 PF02591.15 KKK41333.1 - 0.09 13.0 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain DZR PF12773.7 KKK41333.1 - 0.12 12.4 0.4 0.4 10.7 0.4 1.7 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 KKK41333.1 - 0.15 12.2 0.3 0.32 11.1 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Amidohydro_3 PF07969.11 KKK41335.1 - 1.2e-73 249.2 0.0 1.4e-73 249.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KKK41335.1 - 4.6e-05 22.9 0.7 0.035 13.4 0.2 2.9 2 1 0 2 2 2 2 Amidohydrolase family Cu2_monoox_C PF03712.15 KKK41335.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain HATPase_c PF02518.26 KKK41336.1 - 3.6e-14 53.2 1.9 1.8e-13 51.0 0.9 2.3 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 KKK41336.1 - 3.8e-07 30.5 0.0 6.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KKK41336.1 - 1e-05 26.2 0.0 1.7e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain HATPase_c_5 PF14501.6 KKK41336.1 - 0.008 16.1 8.8 0.014 15.2 0.9 3.5 2 1 2 4 4 4 2 GHKL domain DUF3232 PF11554.8 KKK41336.1 - 0.017 15.5 4.0 2.1 8.8 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3232) DUF4306 PF14154.6 KKK41337.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Response_reg PF00072.24 KKK41338.1 - 6.2e-22 77.9 1.4 7e-22 77.7 1.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain NTP_transf_3 PF12804.7 KKK41339.1 - 2.8e-05 24.5 0.0 2.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transf_3 PF12804.7 KKK41342.1 - 8.6e-19 68.5 0.0 1.1e-18 68.1 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain GATase_7 PF13537.6 KKK41343.1 - 2.4e-14 53.3 0.0 4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKK41343.1 - 4.5e-14 52.8 0.0 7.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KKK41343.1 - 7e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UDPG_MGDP_dh_N PF03721.14 KKK41343.1 - 0.041 13.5 0.2 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pribosyltran PF00156.27 KKK41344.1 - 0.038 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Robl_LC7 PF03259.17 KKK41347.1 - 1.5e-14 53.5 0.2 2e-14 53.1 0.2 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain Peptidase_M24 PF00557.24 KKK41348.1 - 4.4e-31 108.2 0.0 7.4e-31 107.5 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Glycos_transf_1 PF00534.20 KKK41349.1 - 3.4e-37 127.6 0.1 6.3e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK41349.1 - 2.3e-25 89.6 0.0 3.7e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK41349.1 - 2.8e-16 60.0 0.0 5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KKK41349.1 - 1.4e-10 41.4 0.0 2.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 KKK41349.1 - 3e-06 26.2 0.2 5.2e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 20 Glyco_trans_4_2 PF13477.6 KKK41349.1 - 0.00011 22.2 0.1 0.00027 21.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_4_4 PF13579.6 KKK41349.1 - 0.0084 16.6 0.0 0.019 15.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain DUF354 PF04007.12 KKK41350.1 - 3e-43 148.2 1.1 3.5e-43 148.0 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF354) MazG PF03819.17 KKK41351.1 - 1.5e-08 34.7 0.1 1.8e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain RecG_N PF17190.4 KKK41351.1 - 0.0063 17.2 0.2 0.0079 16.9 0.2 1.2 1 0 0 1 1 1 1 RecG N-terminal helical domain MazG-like PF12643.7 KKK41351.1 - 0.0098 16.1 0.1 0.015 15.6 0.1 1.2 1 0 0 1 1 1 1 MazG-like family Sec61_beta PF03911.16 KKK41352.1 - 7.3e-12 45.1 2.1 8.9e-12 44.8 2.1 1.1 1 0 0 1 1 1 1 Sec61beta family Ribophorin_I PF04597.14 KKK41353.1 - 4.6e-16 59.1 4.4 7.1e-12 45.2 0.0 3.2 1 1 1 2 2 2 2 Ribophorin I Streptin-Immun PF11083.8 KKK41353.1 - 0.015 15.7 3.9 0.015 15.7 3.9 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein BRI3BP PF14965.6 KKK41353.1 - 0.11 12.0 0.3 0.29 10.6 0.3 1.6 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Trm112p PF03966.16 KKK41354.1 - 8.2e-10 39.1 0.0 3.7e-08 33.8 0.0 2.4 1 1 0 1 1 1 1 Trm112p-like protein DUF2034 PF10356.9 KKK41355.1 - 0.012 15.0 0.4 0.018 14.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) Cytochrome_C7 PF14522.6 KKK41355.1 - 0.048 13.7 13.7 0.44 10.6 4.2 3.2 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c RuvB_C PF05491.13 KKK41355.1 - 0.052 13.4 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 RuvB C-terminal winged helix domain Cytochrom_CIII PF02085.16 KKK41355.1 - 0.27 11.6 7.4 6.1 7.2 2.5 3.1 3 1 0 3 3 3 0 Class III cytochrome C family c-SKI_SMAD_bind PF08782.10 KKK41355.1 - 0.89 9.8 7.7 0.13 12.5 1.5 2.6 3 1 0 3 3 3 0 c-SKI Smad4 binding domain putAbiC PF16872.5 KKK41355.1 - 0.9 10.3 5.4 0.34 11.6 1.8 2.2 2 1 0 2 2 2 0 Putative phage abortive infection protein Glycos_transf_4 PF00953.21 KKK41356.1 - 3.2e-28 98.7 13.9 3.2e-28 98.7 13.9 3.7 3 2 1 4 4 4 1 Glycosyl transferase family 4 DUF2681 PF10883.8 KKK41356.1 - 0.088 13.2 0.1 0.86 10.0 0.1 2.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_M48 PF01435.18 KKK41357.1 - 9.9e-18 64.6 0.2 3.6e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 KKK41357.1 - 8.7e-05 21.9 5.5 0.00024 20.4 5.5 1.7 1 0 0 1 1 1 1 BlaR1 peptidase M56 Methyltransf_20 PF12147.8 KKK41357.1 - 0.031 13.4 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase GCH_III PF05165.12 KKK41357.1 - 0.08 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 GTP cyclohydrolase III UbiA PF01040.18 KKK41358.1 - 1.3e-22 80.4 9.1 1.3e-22 80.4 9.1 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family SBP_bac_5 PF00496.22 KKK41359.1 - 1.5e-39 136.1 1.5 1.8e-39 135.8 1.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle E1-E2_ATPase PF00122.20 KKK41362.1 - 1.1e-48 165.1 1.0 1.1e-48 165.1 1.0 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK41362.1 - 4.9e-31 107.9 5.4 4.9e-31 107.9 5.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KKK41362.1 - 1.1e-20 73.0 0.1 3.3e-20 71.6 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KKK41362.1 - 8.5e-19 68.7 0.9 2.5e-18 67.1 0.9 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK41362.1 - 3.3e-16 59.1 0.0 7.4e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 KKK41362.1 - 0.0013 19.2 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK41362.1 - 0.0049 16.6 3.2 0.08 12.7 0.4 2.5 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase EXS PF03124.14 KKK41362.1 - 0.11 11.8 7.5 0.16 11.3 5.9 2.0 2 0 0 2 2 2 0 EXS family ORMDL PF04061.14 KKK41365.1 - 0.037 13.8 0.2 0.037 13.8 0.2 2.0 2 1 0 2 2 2 0 ORMDL family RecR PF02132.15 KKK41366.1 - 0.0014 18.1 1.3 0.0024 17.4 1.3 1.3 1 0 0 1 1 1 1 RecR protein zinc_ribbon_15 PF17032.5 KKK41366.1 - 0.018 15.7 0.2 0.026 15.3 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK41366.1 - 0.1 12.0 3.0 0.17 11.4 3.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK41366.1 - 0.77 9.6 4.6 8.6 6.2 4.6 2.1 1 1 0 1 1 1 0 zinc-ribbon domain ParD_antitoxin PF03693.14 KKK41367.1 - 9.1e-05 22.8 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Sigma54_CBD PF04963.13 KKK41367.1 - 0.039 13.8 1.9 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain PCI PF01399.27 KKK41367.1 - 0.11 13.0 9.7 0.18 12.4 5.6 2.5 1 1 1 2 2 2 0 PCI domain zf-CHCC PF10276.9 KKK41368.1 - 0.00075 19.5 1.7 0.12 12.5 0.6 2.8 2 0 0 2 2 2 1 Zinc-finger domain Rad50_zn_hook PF04423.14 KKK41368.1 - 0.002 17.9 1.2 0.032 14.1 0.2 2.7 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Di19 PF05605.12 KKK41368.1 - 0.003 17.8 4.3 1.7 9.0 0.3 3.3 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 KKK41368.1 - 0.0078 15.6 4.3 0.63 9.5 0.2 3.1 3 0 0 3 3 3 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KKK41368.1 - 0.02 14.4 8.8 0.36 10.4 0.5 3.6 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 KKK41368.1 - 0.066 13.0 2.0 1.8 8.4 0.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF2256 PF10013.9 KKK41368.1 - 0.081 13.1 4.2 0.13 12.4 0.6 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HC_2 PF13913.6 KKK41368.1 - 0.23 11.4 11.5 0.43 10.5 4.3 3.3 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 KKK41368.1 - 0.25 11.6 2.1 5.7 7.3 0.1 2.9 3 0 0 3 3 2 0 zinc-ribbon DUF2752 PF10825.8 KKK41368.1 - 0.41 10.7 0.2 0.41 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zf-H2C2_2 PF13465.6 KKK41368.1 - 0.46 11.0 5.0 18 6.0 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger double domain UPF0547 PF10571.9 KKK41368.1 - 0.48 10.5 6.5 2.5 8.3 0.6 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 KKK41368.1 - 0.5 10.5 5.6 1.3 9.2 0.5 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 KKK41368.1 - 1.2 9.0 5.8 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KKK41368.1 - 2.6 8.1 8.3 0.73 9.8 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.26 KKK41368.1 - 3.8 8.1 8.4 2.2 8.9 0.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type C1_1 PF00130.22 KKK41368.1 - 4.4 7.3 8.5 15 5.6 0.6 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_4 PF13894.6 KKK41368.1 - 6.2 7.9 11.3 1.2 10.2 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger hNIFK_binding PF12196.8 KKK41368.1 - 8.9 5.9 7.3 0.4 10.2 0.8 2.2 2 1 0 2 2 1 0 FHA Ki67 binding domain of hNIFK JAB PF01398.21 KKK41369.1 - 2e-12 47.1 0.0 5.3e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KKK41369.1 - 0.00019 21.2 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SNAP PF14938.6 KKK41369.1 - 0.0046 16.4 3.3 0.0051 16.3 0.4 2.0 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KKK41369.1 - 0.031 14.6 0.6 4.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2358 PF10184.9 KKK41369.1 - 0.035 14.4 0.9 1.5 9.2 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2358) Patched PF02460.18 KKK41369.1 - 0.081 11.0 0.2 0.11 10.5 0.2 1.1 1 0 0 1 1 1 0 Patched family TPR_8 PF13181.6 KKK41369.1 - 0.26 11.6 4.1 3 8.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPP_enzyme_C PF02775.21 KKK41370.1 - 7e-20 71.4 0.0 1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KKK41371.1 - 2e-08 34.0 0.0 2.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CoA_transf_3 PF02515.17 KKK41373.1 - 2.8e-93 313.0 0.0 3.1e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III tRNA-synt_2 PF00152.20 KKK41376.1 - 8e-77 258.4 0.0 1e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK41376.1 - 7.1e-16 58.0 0.1 1.3e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain F420_ligase PF01996.16 KKK41377.1 - 4.4e-50 170.3 1.7 5.2e-50 170.1 1.7 1.1 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Succ_CoA_lig PF13607.6 KKK41378.1 - 6.5e-35 119.9 0.0 1.4e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK41378.1 - 7.2e-07 29.7 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK41378.1 - 0.0013 19.4 0.1 0.0031 18.2 0.1 1.7 1 1 0 1 1 1 1 CoA binding domain Asp2 PF16929.5 KKK41378.1 - 0.065 12.2 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Pterin_bind PF00809.22 KKK41379.1 - 8.8e-50 169.7 0.0 1e-49 169.4 0.0 1.0 1 0 0 1 1 1 1 Pterin binding enzyme DNA_gyraseB PF00204.25 KKK41380.1 - 6.5e-55 185.3 0.5 6.5e-55 185.3 0.5 1.7 2 0 0 2 2 2 1 DNA gyrase B DNA_gyraseB_C PF00986.21 KKK41380.1 - 1.6e-23 82.6 0.9 3.7e-23 81.5 0.9 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 KKK41380.1 - 3e-22 79.2 0.2 2.3e-21 76.4 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KKK41380.1 - 5.8e-18 65.0 0.0 1.8e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 KKK41380.1 - 0.0046 16.8 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIID_NTD2 PF04494.15 KKK41380.1 - 0.028 14.7 0.1 0.12 12.6 0.1 2.2 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain HATPase_c PF02518.26 KKK41384.1 - 1.6e-14 54.4 0.2 2.7e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK41384.1 - 0.00059 19.7 0.9 0.0014 18.5 0.9 1.6 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KKK41384.1 - 0.039 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain NCE101 PF11654.8 KKK41384.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Non-classical export protein 1 PAS_3 PF08447.12 KKK41385.1 - 4.1e-45 152.0 1.4 3.1e-17 62.6 0.0 4.7 5 0 0 5 5 4 3 PAS fold MEDS PF14417.6 KKK41385.1 - 3.3e-44 150.6 0.0 6.6e-44 149.6 0.0 1.6 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain PAS PF00989.25 KKK41385.1 - 5e-43 145.7 0.1 9.6e-13 48.1 0.0 4.5 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 KKK41385.1 - 1.3e-38 131.6 0.0 5.7e-10 39.4 0.0 4.4 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 KKK41385.1 - 2.3e-38 130.6 11.6 2.6e-13 50.1 0.1 5.1 5 0 0 5 5 5 4 PAS domain HATPase_c PF02518.26 KKK41385.1 - 1e-24 87.2 0.6 2.7e-24 85.8 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KKK41385.1 - 1.1e-16 60.4 0.0 0.00018 21.5 0.0 4.7 4 0 0 4 4 4 3 PAS domain HisKA PF00512.25 KKK41385.1 - 2.3e-11 43.6 0.6 1.2e-10 41.2 0.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 KKK41385.1 - 2.3e-05 24.5 0.0 0.082 13.0 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_7 PF12860.7 KKK41385.1 - 0.00015 21.9 0.5 0.72 10.0 0.0 4.7 4 1 0 4 4 4 1 PAS fold HATPase_c_3 PF13589.6 KKK41385.1 - 0.013 15.3 0.1 0.037 13.8 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SirA PF10747.9 KKK41385.1 - 0.02 15.3 1.0 0.15 12.4 1.0 2.6 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA PAS_10 PF13596.6 KKK41385.1 - 0.041 14.5 2.0 3.4 8.3 0.0 3.8 4 0 0 4 4 4 0 PAS domain HATPase_c_5 PF14501.6 KKK41385.1 - 0.042 13.7 0.9 0.43 10.5 0.9 2.6 1 1 0 1 1 1 0 GHKL domain HATPase_c_2 PF13581.6 KKK41385.1 - 0.059 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Maelstrom PF13017.6 KKK41385.1 - 1.6 8.3 7.4 5.2 6.7 0.3 3.0 2 2 0 2 2 2 0 piRNA pathway germ-plasm component GP24_25 PF17388.2 KKK41386.1 - 0.1 12.6 1.4 6.8 6.7 0.1 2.6 1 1 0 2 2 2 0 Tail assembly gene products 24 & 25 Na_Ca_ex PF01699.24 KKK41387.1 - 1.6e-32 112.5 42.5 9.3e-18 64.6 17.7 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein zinc_ribbon_15 PF17032.5 KKK41388.1 - 0.0075 17.0 1.2 0.009 16.7 1.2 1.3 1 0 0 1 1 1 1 zinc-ribbon family zf-FCS PF06467.14 KKK41388.1 - 0.013 15.4 1.7 0.7 9.9 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif NosL PF05573.12 KKK41388.1 - 0.025 14.9 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 NosL DUF2116 PF09889.9 KKK41388.1 - 0.029 14.3 0.2 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) UDPG_MGDP_dh_N PF03721.14 KKK41389.1 - 5.4e-45 153.3 0.2 4.4e-44 150.3 0.0 2.1 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KKK41389.1 - 5.3e-30 103.5 0.1 1.3e-29 102.3 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KKK41389.1 - 1.9e-27 95.8 0.0 4.5e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 2-Hacid_dh_C PF02826.19 KKK41389.1 - 0.015 14.6 0.1 1.3 8.4 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF501 PF04417.12 KKK41390.1 - 0.17 11.7 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DHDPS PF00701.22 KKK41391.1 - 1.2e-77 260.5 0.2 1.4e-77 260.2 0.2 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fae PF08714.11 KKK41391.1 - 3.2e-52 176.7 0.0 5.5e-52 175.9 0.0 1.4 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) WHIM1 PF15612.6 KKK41391.1 - 0.0057 16.2 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Rick_17kDa_Anti PF05433.15 KKK41391.1 - 0.056 13.3 2.7 0.12 12.3 2.7 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain YbhQ PF11076.8 KKK41393.1 - 8.5 6.4 11.2 0.41 10.7 5.1 2.0 2 1 0 2 2 2 0 Putative inner membrane protein YbhQ AsnC_trans_reg PF01037.21 KKK41394.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.5 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 KKK41394.1 - 0.016 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain AMP-binding PF00501.28 KKK41395.1 - 2.2e-60 204.5 0.0 2.6e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK41395.1 - 5.3e-05 24.1 0.0 0.00012 23.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GBP PF02263.19 KKK41395.1 - 0.087 12.1 0.3 0.15 11.3 0.3 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Sigma54_AID PF00309.20 KKK41395.1 - 4.4 7.2 4.8 1.9 8.4 0.9 2.4 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) PAF-AH_p_II PF03403.13 KKK41396.1 - 5.8e-17 61.3 0.0 8.8e-12 44.2 0.0 3.0 2 1 1 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KKK41396.1 - 1.9e-08 33.9 1.6 0.0012 18.1 1.0 3.6 3 1 1 4 4 4 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KKK41396.1 - 4.7e-08 32.3 0.0 1.5e-07 30.6 0.0 1.8 2 1 0 2 2 2 1 Chlorophyllase enzyme AXE1 PF05448.12 KKK41396.1 - 3.2e-07 29.3 0.0 1.6e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.11 KKK41396.1 - 6.3e-06 25.4 0.0 0.00031 19.9 0.0 2.2 2 0 0 2 2 2 1 Chlorophyllase DLH PF01738.18 KKK41396.1 - 0.00015 21.4 0.0 0.00035 20.2 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KKK41396.1 - 0.00034 20.2 0.0 0.055 12.9 0.0 3.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KKK41396.1 - 0.00051 19.7 0.0 1.2 8.7 0.0 3.0 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KKK41396.1 - 0.0022 18.0 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PhoPQ_related PF10142.9 KKK41396.1 - 0.017 13.8 0.1 0.19 10.4 0.0 2.1 1 1 1 2 2 2 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_6 PF12697.7 KKK41396.1 - 0.022 15.3 0.0 8.2 7.0 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family DDE_Tnp_IS240 PF13610.6 KKK41398.1 - 3.1e-09 37.2 1.7 2.1e-08 34.5 0.8 2.3 2 0 0 2 2 2 1 DDE domain GerE PF00196.19 KKK41398.1 - 0.015 14.8 0.1 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 KKK41398.1 - 0.037 13.8 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Ogr_Delta PF04606.12 KKK41398.1 - 0.04 13.9 1.0 0.12 12.4 1.0 1.8 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.7 KKK41398.1 - 0.049 13.6 1.1 0.1 12.6 1.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 KKK41398.1 - 0.056 13.2 3.1 0.12 12.2 1.6 2.1 1 1 1 2 2 2 0 InsA N-terminal domain Baculo_PEP_C PF04513.12 KKK41398.1 - 0.32 11.0 2.8 1.6 8.7 0.2 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNTTIP1_dimer PF18192.1 KKK41398.1 - 0.32 11.4 5.0 0.45 10.9 1.1 2.8 2 1 1 3 3 3 0 DNTTIP1 dimerisation domain GFO_IDH_MocA PF01408.22 KKK41399.1 - 1.1e-28 100.4 0.2 1.6e-28 99.9 0.2 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KKK41399.1 - 2.7e-05 24.8 0.1 4.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 KKK41399.1 - 0.00013 21.9 0.0 0.0003 20.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.19 KKK41399.1 - 0.0051 16.2 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KKK41399.1 - 0.081 13.5 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 KKK41400.1 - 8.5e-67 225.1 0.8 1e-66 224.8 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK41400.1 - 7.4e-50 169.1 2.5 9.4e-50 168.8 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK41400.1 - 3.8e-08 33.4 1.0 6.2e-08 32.8 1.0 1.3 1 0 0 1 1 1 1 KR domain FAE1_CUT1_RppA PF08392.12 KKK41400.1 - 0.056 12.7 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein LIDHydrolase PF10230.9 KKK41400.1 - 0.14 11.7 0.5 2.9 7.4 0.1 2.1 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase ADC PF06314.11 KKK41401.1 - 1.2e-08 34.8 0.0 1.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NMO PF03060.15 KKK41402.1 - 6.4e-65 219.7 5.1 2.3e-64 217.9 5.1 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK41402.1 - 1.4e-09 37.5 3.3 8.7e-07 28.2 1.4 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK41402.1 - 6.2e-06 25.5 7.2 8.2e-06 25.1 6.9 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KKK41402.1 - 0.00044 19.8 0.8 0.0011 18.5 0.4 2.0 2 1 0 2 2 2 1 Histidine biosynthesis protein Trp_syntA PF00290.20 KKK41402.1 - 0.00047 19.1 0.3 0.021 13.7 0.1 2.4 2 1 0 2 2 2 1 Tryptophan synthase alpha chain G3P_antiterm PF04309.12 KKK41402.1 - 0.00095 18.6 2.3 0.063 12.7 0.1 3.4 4 0 0 4 4 4 1 Glycerol-3-phosphate responsive antiterminator Glu_synthase PF01645.17 KKK41402.1 - 0.0022 17.2 6.3 0.009 15.2 6.3 2.0 1 1 0 1 1 1 1 Conserved region in glutamate synthase Dus PF01207.17 KKK41402.1 - 0.017 14.3 0.3 0.29 10.2 0.1 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) YjeF_N PF03853.15 KKK41402.1 - 0.025 14.5 0.4 0.063 13.2 0.3 1.9 2 1 0 2 2 2 0 YjeF-related protein N-terminus DUF561 PF04481.12 KKK41402.1 - 0.041 13.0 0.8 0.081 12.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF561) ThiG PF05690.14 KKK41402.1 - 0.048 13.0 6.4 0.062 12.6 4.9 1.9 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 KKK41402.1 - 0.06 12.7 0.5 1.3 8.3 0.7 2.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase Prefoldin PF02996.17 KKK41402.1 - 0.094 12.6 0.1 0.38 10.7 0.1 2.1 1 1 0 1 1 1 0 Prefoldin subunit 4HBT_2 PF13279.6 KKK41403.1 - 1e-18 68.0 0.0 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KKK41403.1 - 6.2e-05 22.4 0.4 0.00044 19.6 0.1 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT PF03061.22 KKK41403.1 - 0.00038 20.8 0.0 0.001 19.4 0.0 1.7 1 1 0 1 1 1 1 Thioesterase superfamily AhpC-TSA PF00578.21 KKK41404.1 - 4.6e-33 113.8 0.0 5.3e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK41404.1 - 1.1e-16 60.9 0.0 1.4e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 KKK41404.1 - 0.017 15.1 0.0 0.046 13.6 0.0 1.8 2 1 0 2 2 2 0 SCO1/SenC DUF2540 PF10802.8 KKK41404.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) Nitroreductase PF00881.24 KKK41405.1 - 2.6e-20 73.2 0.1 9.9e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 KKK41405.1 - 1.1e-07 31.7 0.0 7.6e-05 22.4 0.2 2.7 1 1 1 2 2 2 2 Putative TM nitroreductase Inhibitor_I48 PF10467.9 KKK41405.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin Thioredox_DsbH PF03190.15 KKK41406.1 - 2.7e-77 258.3 0.0 6.2e-77 257.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KKK41406.1 - 2.5e-09 37.2 0.0 4.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 KKK41406.1 - 4.2e-06 26.1 0.4 0.0017 17.5 0.0 3.0 3 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KKK41406.1 - 0.00081 18.9 2.0 1.4 8.4 0.0 3.7 3 1 0 4 4 4 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_76 PF03663.14 KKK41406.1 - 0.0017 17.9 0.0 0.76 9.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Thioredoxin_2 PF13098.6 KKK41406.1 - 0.026 14.9 0.0 0.07 13.6 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain LANC_like PF05147.13 KKK41406.1 - 0.059 11.9 1.6 1.4 7.5 0.3 3.1 2 2 0 2 2 2 0 Lanthionine synthetase C-like protein DUF4107 PF13389.6 KKK41406.1 - 0.088 13.0 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) Glyco_hydro_38 PF18438.1 KKK41407.1 - 0.046 13.8 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 DUF1499 PF07386.11 KKK41408.1 - 1.6e-34 119.0 0.0 1.9e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) CDP-OH_P_transf PF01066.21 KKK41410.1 - 3.7e-13 50.0 4.4 3.7e-13 50.0 4.4 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DAP_epimerase PF01678.19 KKK41415.1 - 3.1e-37 127.4 0.1 1.9e-33 115.2 0.0 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 KKK41415.1 - 3.5e-05 23.4 0.0 0.02 14.4 0.0 2.0 1 1 1 2 2 2 2 Phenazine biosynthesis-like protein Draxin PF15550.6 KKK41415.1 - 0.18 11.6 0.2 0.27 11.1 0.2 1.2 1 0 0 1 1 1 0 Draxin TrmB PF01978.19 KKK41416.1 - 8.3e-06 25.6 0.0 2e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB AAA_12 PF13087.6 KKK41416.1 - 0.031 13.9 0.2 0.071 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain PadR PF03551.14 KKK41416.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Gram_pos_anchor PF00746.21 KKK41417.1 - 4.7 7.2 4.6 0.87 9.6 0.6 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Dynein_C PF18199.1 KKK41418.1 - 0.028 13.7 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain CdhD PF03599.16 KKK41419.1 - 4.9e-37 127.5 0.0 6.1e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit CdhD PF03599.16 KKK41420.1 - 5.1e-13 48.5 0.0 8.7e-11 41.1 0.0 2.3 1 1 1 2 2 2 2 CO dehydrogenase/acetyl-CoA synthase delta subunit Acetyltransf_9 PF13527.7 KKK41421.1 - 1.8e-18 66.8 0.0 2e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK41421.1 - 0.0014 18.8 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK41421.1 - 0.0031 17.9 0.0 0.0039 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pantoate_transf PF02548.15 KKK41423.1 - 4.5e-106 354.0 1.3 5.2e-106 353.8 1.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KKK41423.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Methyltransf_11 PF08241.12 KKK41424.1 - 2.2e-23 82.7 0.0 3.4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK41424.1 - 1.3e-19 70.7 0.0 2.2e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK41424.1 - 2.4e-15 56.7 0.1 3.3e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK41424.1 - 8.1e-12 45.0 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KKK41424.1 - 2e-11 44.0 0.0 3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK41424.1 - 4.9e-11 43.2 0.0 7.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KKK41424.1 - 1.3e-08 34.5 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 KKK41424.1 - 1.4e-05 25.0 0.0 6.2e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 KKK41424.1 - 5.4e-05 22.6 0.0 7.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK41424.1 - 0.0013 18.3 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KKK41424.1 - 0.0039 16.6 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KKK41424.1 - 0.024 13.6 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KKK41424.1 - 0.031 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 KKK41424.1 - 0.042 13.5 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 KKK41424.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TusA PF01206.17 KKK41425.1 - 1.5e-18 66.4 0.0 1.6e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DrsE PF02635.15 KKK41426.1 - 1.9e-23 83.0 0.0 2.3e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 KKK41426.1 - 5.2e-05 23.2 1.7 0.00012 22.1 0.4 1.8 1 1 1 2 2 2 1 DsrE/DsrF/DrsH-like family DsrH PF04077.12 KKK41426.1 - 0.0011 19.0 0.0 0.0062 16.6 0.0 2.1 1 1 0 1 1 1 1 DsrH like protein PAR1 PF06521.11 KKK41426.1 - 0.018 14.6 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 PAR1 protein LysR_substrate PF03466.20 KKK41427.1 - 1.1e-23 83.7 0.0 1.5e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 KKK41427.1 - 1.6e-11 43.9 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 KKK41427.1 - 0.00019 21.2 0.1 0.00046 20.0 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Mga PF05043.13 KKK41427.1 - 0.0005 20.6 3.3 0.0039 17.7 0.6 3.2 3 0 0 3 3 3 1 Mga helix-turn-helix domain HTH_50 PF18024.1 KKK41427.1 - 0.0046 16.5 0.1 0.0095 15.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain PBP_like PF12727.7 KKK41427.1 - 0.013 14.6 0.0 0.091 11.9 0.0 2.1 1 1 0 1 1 1 0 PBP superfamily domain HTH_10 PF04967.12 KKK41427.1 - 0.026 14.3 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain PBP_like_2 PF12849.7 KKK41427.1 - 0.033 13.9 0.0 1.8 8.2 0.0 2.5 2 1 1 3 3 3 0 PBP superfamily domain HTH_6 PF01418.17 KKK41427.1 - 0.046 13.7 0.2 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_11 PF08279.12 KKK41427.1 - 0.061 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 HTH domain Phage_CI_repr PF07022.13 KKK41427.1 - 0.07 13.2 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DUF4994 PF16385.5 KKK41428.1 - 0.23 11.4 1.0 0.43 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function OppC_N PF12911.7 KKK41428.1 - 1.8 8.6 4.9 15 5.6 0.8 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C CoA_binding_2 PF13380.6 KKK41430.1 - 2.3e-07 31.3 0.0 5.9e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 KKK41430.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain TetR_N PF00440.23 KKK41433.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family zf-Di19 PF05605.12 KKK41433.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Acetyltransf_7 PF13508.7 KKK41434.1 - 2.1e-05 24.8 0.2 3.4e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK41434.1 - 3e-05 24.2 0.0 4.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK41434.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Casc1 PF12366.8 KKK41434.1 - 0.07 12.6 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Lig_C PF18330.1 KKK41435.1 - 0.15 12.1 4.5 3.9 7.5 0.3 2.9 2 1 1 3 3 3 0 Ligase Pab1020 C-terminal region SRI PF08236.11 KKK41436.1 - 0.15 12.3 2.3 15 5.8 0.1 3.6 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain MtrH PF02007.18 KKK41437.1 - 3.9e-55 187.1 0.0 5e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit Gtr1_RagA PF04670.12 KKK41438.1 - 4.7e-19 68.7 0.5 4.7e-19 68.7 0.5 2.4 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK41438.1 - 2.2e-16 59.8 0.0 5.1e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK41438.1 - 3.7e-08 33.6 0.0 8.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK41438.1 - 3.2e-06 26.8 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK41438.1 - 7.9e-06 25.4 3.1 2.1e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AIRS_C PF02769.22 KKK41439.1 - 3.7e-12 46.6 0.0 6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KKK41439.1 - 4.6e-12 46.4 0.0 1e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ACT PF01842.25 KKK41440.1 - 0.0012 18.6 0.9 0.0053 16.5 0.1 2.1 2 0 0 2 2 2 1 ACT domain DUF370 PF04025.12 KKK41440.1 - 0.0061 16.7 0.3 0.01 16.0 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF370) ACT_4 PF13291.6 KKK41440.1 - 0.039 14.5 3.5 0.45 11.1 0.0 2.9 1 1 2 3 3 3 0 ACT domain Homoserine_dh PF00742.19 KKK41441.1 - 6.2e-49 166.2 0.1 1.2e-48 165.3 0.1 1.4 1 1 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KKK41441.1 - 2.6e-06 28.1 0.0 1.1e-05 26.0 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain LDcluster4 PF18306.1 KKK41442.1 - 1.1e-27 96.6 0.1 1.2e-27 96.4 0.1 1.0 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 KKK41442.1 - 0.00013 22.0 0.0 0.00037 20.6 0.0 1.7 1 1 0 1 1 1 1 Possible lysine decarboxylase DUF2375 PF09558.10 KKK41442.1 - 0.051 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Catalase_C PF18011.1 KKK41442.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases PALP PF00291.25 KKK41443.1 - 2.9e-19 69.6 0.0 6.1e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 KKK41443.1 - 9.7e-15 54.5 0.0 3.1e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus DUF4030 PF13222.6 KKK41443.1 - 0.019 15.1 0.1 0.048 13.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) Gtr1_RagA PF04670.12 KKK41444.1 - 3.3e-24 85.5 0.1 4.3e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK41444.1 - 1.6e-16 60.3 0.0 2.3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK41444.1 - 3e-05 23.5 0.1 0.00019 20.9 0.0 2.2 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK41444.1 - 7e-05 23.0 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK41444.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FYDLN_acid PF09538.10 KKK41446.1 - 0.0017 19.0 0.6 0.0041 17.8 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zinc_ribbon_2 PF13240.6 KKK41446.1 - 0.012 15.3 1.4 0.02 14.6 1.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KKK41446.1 - 0.021 14.8 0.8 0.037 14.0 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KKK41446.1 - 0.041 13.4 0.4 0.084 12.4 0.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4162 PF13732.6 KKK41446.1 - 0.28 11.9 0.2 0.28 11.9 0.2 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4162) NERD PF08378.11 KKK41447.1 - 1.6e-05 25.3 0.1 3.4e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Nuclease-related domain NRDD PF13597.6 KKK41448.1 - 3.5e-66 224.2 3.7 5.1e-66 223.6 3.7 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Arf PF00025.21 KKK41449.1 - 5.3e-15 55.3 0.0 8.5e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK41449.1 - 2e-09 37.2 0.4 1.8e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KKK41449.1 - 2.6e-06 27.7 0.0 5.5e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK41449.1 - 1.6e-05 25.0 0.0 4e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK41449.1 - 3.1e-05 23.3 3.2 0.011 14.9 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KKK41449.1 - 0.00022 20.9 0.1 0.0005 19.7 0.0 1.6 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 KKK41449.1 - 0.002 17.6 0.2 0.0042 16.5 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Folliculin PF11704.8 KKK41449.1 - 0.017 15.0 0.1 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PriA_CRR PF18319.1 KKK41454.1 - 0.0076 16.2 2.0 1.1 9.3 0.4 3.0 2 1 0 2 2 2 2 PriA DNA helicase Cys-rich region (CRR) domain PEMT PF04191.13 KKK41455.1 - 9.2e-16 58.2 0.7 9.2e-16 58.2 0.7 2.0 2 1 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 KKK41455.1 - 0.00015 22.2 0.0 0.00015 22.2 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KKK41455.1 - 0.0011 17.8 0.0 0.0011 17.8 0.0 1.7 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KKK41455.1 - 0.004 17.2 3.2 0.0061 16.6 3.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PalH PF08733.10 KKK41455.1 - 0.5 9.3 7.6 0.77 8.7 7.6 1.5 1 1 0 1 1 1 0 PalH/RIM21 HMA PF00403.26 KKK41456.1 - 2.2e-13 50.4 0.1 2.4e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain FTR1 PF03239.14 KKK41457.1 - 1.2e-37 129.8 13.5 1.2e-37 129.8 13.5 1.3 2 0 0 2 2 2 1 Iron permease FTR1 family Holin_BhlA PF10960.8 KKK41457.1 - 0.96 9.5 3.2 3.8 7.5 0.2 2.9 2 1 1 3 3 3 0 BhlA holin family MraZ PF02381.18 KKK41458.1 - 0.0017 18.3 0.4 0.0044 17.0 0.1 1.8 1 1 0 2 2 2 1 MraZ protein, putative antitoxin-like MazE_antitoxin PF04014.18 KKK41458.1 - 0.0045 16.9 2.4 0.011 15.6 2.4 1.6 1 1 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PIN PF01850.21 KKK41459.1 - 9.2e-15 55.2 0.7 4e-14 53.2 0.7 1.7 1 1 0 1 1 1 1 PIN domain Kin17_mid PF10357.9 KKK41459.1 - 0.014 15.3 2.1 0.03 14.3 0.3 1.9 1 1 1 2 2 2 0 Domain of Kin17 curved DNA-binding protein Polbeta PF18765.1 KKK41460.1 - 6.1e-15 55.1 0.1 8.1e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK41460.1 - 3.2e-05 24.1 0.0 4.8e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyltransferase domain DUF2577 PF10844.8 KKK41460.1 - 0.062 13.5 0.1 0.17 12.1 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2577) DUF86 PF01934.17 KKK41461.1 - 8.8e-19 67.5 0.1 1.1e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 YhfH PF14149.6 KKK41462.1 - 0.019 15.0 4.2 0.027 14.5 0.8 2.1 2 0 0 2 2 2 0 YhfH-like protein zinc_ribbon_4 PF13717.6 KKK41462.1 - 0.31 11.0 7.7 3 7.9 1.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Ldh_1_N PF00056.23 KKK41464.1 - 1.6e-41 141.7 0.0 2.3e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KKK41464.1 - 2.2e-33 115.6 0.0 6.6e-33 114.0 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KKK41464.1 - 0.00023 20.8 3.7 0.0029 17.2 0.1 2.6 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.14 KKK41464.1 - 0.0067 16.0 0.2 0.019 14.6 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KKK41464.1 - 0.065 13.7 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3797 PF12677.7 KKK41464.1 - 0.07 13.0 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) TrkA_N PF02254.18 KKK41464.1 - 0.078 13.2 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 KKK41464.1 - 0.16 11.3 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family PALP PF00291.25 KKK41465.1 - 1e-57 195.8 0.0 1.8e-57 195.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_S24 PF00717.23 KKK41465.1 - 0.041 13.8 0.1 0.68 9.9 0.2 2.7 2 1 0 2 2 2 0 Peptidase S24-like PadR PF03551.14 KKK41466.1 - 0.0038 17.1 1.5 0.2 11.6 0.0 3.0 3 0 0 3 3 3 1 Transcriptional regulator PadR-like family NYD-SP28_assoc PF14775.6 KKK41466.1 - 0.041 14.0 0.6 0.097 12.8 0.6 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain Cullin_Nedd8 PF10557.9 KKK41466.1 - 0.38 10.8 9.7 0.56 10.3 0.3 3.6 3 0 0 3 3 3 0 Cullin protein neddylation domain SpoVIF PF14069.6 KKK41466.1 - 9.8 6.0 8.3 23 4.9 0.0 4.2 4 0 0 4 4 4 0 Stage VI sporulation protein F Fer4_8 PF13183.6 KKK41469.1 - 4.3e-07 30.3 17.1 0.00055 20.3 0.1 2.9 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK41469.1 - 1.4e-05 25.6 17.3 0.00041 20.9 0.2 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41469.1 - 1.7e-05 25.3 13.3 1.7e-05 25.3 13.3 2.6 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41469.1 - 4.4e-05 23.1 3.7 4.4e-05 23.1 3.7 3.9 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK41469.1 - 6.7e-05 22.7 13.4 0.0015 18.5 3.7 3.8 3 1 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK41469.1 - 0.00035 20.6 21.6 0.0017 18.4 0.1 3.0 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK41469.1 - 0.001 19.3 0.3 0.001 19.3 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41469.1 - 0.0014 18.7 0.9 0.0014 18.7 0.9 3.4 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41469.1 - 0.0019 18.2 2.3 0.0019 18.2 2.3 3.5 4 1 0 4 4 4 1 4Fe-4S binding domain Fer4_9 PF13187.6 KKK41469.1 - 0.0033 17.6 24.7 0.026 14.7 18.2 3.2 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK41469.1 - 0.013 16.4 0.1 0.013 16.4 0.1 3.3 2 1 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK41469.1 - 0.036 14.6 3.3 0.036 14.6 3.3 3.8 4 1 0 4 4 4 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK41469.1 - 0.12 13.3 0.3 0.12 13.3 0.3 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK41469.1 - 9.3 7.4 34.7 0.25 12.3 3.6 4.3 4 1 1 5 5 4 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK41470.1 - 4.3e-30 104.4 20.8 7.2e-30 103.7 15.6 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK41470.1 - 3.4e-06 27.4 14.3 1.8e-05 25.1 14.3 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41470.1 - 4.7e-06 26.6 14.1 0.0044 17.1 0.2 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41470.1 - 7.8e-06 25.5 24.1 0.00085 19.0 4.8 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK41470.1 - 2.8e-05 24.0 16.7 0.0028 17.6 2.4 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK41470.1 - 0.00087 19.4 22.8 0.0079 16.3 4.0 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41470.1 - 0.003 17.7 20.6 0.057 13.6 1.4 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK41470.1 - 0.0054 17.1 22.2 0.0086 16.5 1.5 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK41470.1 - 0.006 17.1 23.0 0.071 13.7 2.6 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41470.1 - 0.0076 16.8 20.2 1.5 9.4 20.4 2.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41470.1 - 0.18 12.0 20.5 0.23 11.6 3.6 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK41470.1 - 0.24 11.6 12.7 0.071 13.3 1.0 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK41470.1 - 0.53 11.3 21.1 0.17 12.9 1.5 3.1 1 1 2 3 3 3 0 4Fe-4S double cluster binding domain NAD_binding_1 PF00175.21 KKK41471.1 - 9.5e-14 52.0 0.0 1.5e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 KKK41471.1 - 3.5e-10 39.5 2.9 7.1e-10 38.5 2.9 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 KKK41471.1 - 6.2e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain CIAPIN1 PF05093.13 KKK41471.1 - 0.025 15.1 0.1 0.063 13.8 0.1 1.6 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MFS_1 PF07690.16 KKK41472.1 - 4.3e-29 101.6 42.7 9.3e-26 90.6 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK41472.1 - 1.3e-09 37.5 10.1 1.3e-09 37.5 10.1 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter Tail_VII PF17091.5 KKK41472.1 - 0.059 13.2 1.0 0.059 13.2 1.0 3.3 3 0 0 3 3 3 0 Inovirus G7P protein G0-G1_switch_2 PF15103.6 KKK41472.1 - 0.082 13.3 0.2 15 6.0 0.0 2.8 2 1 0 2 2 2 0 G0/G1 switch protein 2 DUF3899 PF13038.6 KKK41473.1 - 0.084 13.4 1.4 0.09 13.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF4752 PF15944.5 KKK41475.1 - 0.021 14.8 1.5 0.062 13.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) TpcC PF12642.7 KKK41476.1 - 0.11 12.2 0.2 0.17 11.6 0.2 1.2 1 0 0 1 1 1 0 Conjugative transposon protein TcpC AMP-binding PF00501.28 KKK41480.1 - 3.3e-57 194.0 0.0 4e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK41480.1 - 1.4e-08 35.6 0.0 2.9e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IL1 PF00340.19 KKK41480.1 - 0.31 10.7 1.3 0.62 9.7 0.4 2.0 2 0 0 2 2 2 0 Interleukin-1 / 18 Polyketide_cyc2 PF10604.9 KKK41481.1 - 0.018 15.3 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF2274 PF10038.9 KKK41481.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) AMP-binding PF00501.28 KKK41482.1 - 5.3e-62 209.8 0.0 6.2e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK41482.1 - 0.00039 21.3 0.0 0.0011 19.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OTCace PF00185.24 KKK41483.1 - 1.6e-16 60.7 0.0 2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KKK41483.1 - 0.042 13.9 0.1 0.094 12.7 0.1 1.6 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace_N PF02729.21 KKK41484.1 - 7.1e-19 68.3 0.2 7.6e-19 68.2 0.2 1.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ABC_tran_CTD PF16326.5 KKK41485.1 - 0.00071 19.8 7.1 0.038 14.2 0.1 2.5 2 1 0 2 2 2 1 ABC transporter C-terminal domain T3SSipB PF16535.5 KKK41485.1 - 0.0012 19.4 1.4 0.0016 19.0 1.4 1.2 1 0 0 1 1 1 1 Type III cell invasion protein SipB Spc7 PF08317.11 KKK41485.1 - 0.0022 16.9 9.2 0.0079 15.1 9.2 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein DHR10 PF18595.1 KKK41485.1 - 0.04 14.0 5.7 1 9.4 0.3 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain LBP_BPI_CETP PF01273.25 KKK41485.1 - 0.074 12.6 0.8 0.14 11.8 0.8 1.4 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Rx_N PF18052.1 KKK41485.1 - 0.087 13.1 3.8 2.8 8.3 0.1 2.4 1 1 1 2 2 2 0 Rx N-terminal domain LPD1 PF18796.1 KKK41485.1 - 0.11 12.7 1.5 3.5 7.8 0.1 2.4 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 1 SirA PF10747.9 KKK41485.1 - 0.11 12.8 11.7 1.6 9.0 4.0 2.2 1 1 0 2 2 2 0 Sporulation inhibitor of replication protein SirA CBP_BcsQ PF06564.12 KKK41485.1 - 0.16 11.4 0.0 0.19 11.2 0.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ DUF4404 PF14357.6 KKK41485.1 - 0.17 12.6 3.1 0.23 12.1 1.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Med9 PF07544.13 KKK41485.1 - 0.17 12.0 10.6 2 8.6 0.5 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MCPsignal PF00015.21 KKK41485.1 - 0.21 11.4 4.1 0.31 10.8 1.1 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GldM_N PF12081.8 KKK41485.1 - 0.25 11.4 12.7 3.4 7.7 12.4 2.0 1 1 1 2 2 2 0 GldM N-terminal domain Seryl_tRNA_N PF02403.22 KKK41485.1 - 0.28 11.4 15.3 0.16 12.2 2.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_N PF02465.18 KKK41485.1 - 0.29 11.8 4.4 2 9.2 4.4 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Cytochrom_C_2 PF01322.20 KKK41485.1 - 0.3 12.0 2.9 0.81 10.6 0.7 2.0 1 1 1 2 2 2 0 Cytochrome C' TadF PF16964.5 KKK41485.1 - 0.35 10.6 3.1 0.55 10.0 3.1 1.3 1 1 0 1 1 1 0 Putative tight adherence pilin protein F ThylakoidFormat PF11264.8 KKK41485.1 - 0.42 10.3 7.7 0.19 11.4 2.0 2.0 2 0 0 2 2 2 0 Thylakoid formation protein DUF1664 PF07889.12 KKK41485.1 - 0.45 10.6 7.6 0.97 9.5 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PSII_Pbs27 PF13326.6 KKK41485.1 - 0.46 10.8 4.5 5.1 7.4 1.1 2.1 1 1 1 2 2 2 0 Photosystem II Pbs27 YtxH PF12732.7 KKK41485.1 - 0.97 10.0 5.6 6.8 7.3 0.3 2.5 1 1 1 2 2 2 0 YtxH-like protein DUF3810 PF12725.7 KKK41485.1 - 1.7 7.9 6.9 5.4 6.3 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) TMPIT PF07851.13 KKK41485.1 - 2.6 7.2 10.7 0.68 9.1 6.2 1.8 1 1 1 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 KKK41485.1 - 3.6 7.8 10.1 6.5 6.9 9.6 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 KKK41485.1 - 3.7 7.6 9.8 8.6 6.4 3.2 2.5 1 1 1 2 2 2 0 FlxA-like protein DUF2203 PF09969.9 KKK41485.1 - 5.7 7.7 6.4 1.4e+02 3.2 6.4 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ACCA PF03255.14 KKK41485.1 - 5.9 6.7 9.4 1.5 8.7 1.5 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FlaC_arch PF05377.11 KKK41485.1 - 6.5 7.2 12.7 1.6 9.1 0.6 3.1 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) NACHT PF05729.12 KKK41486.1 - 0.031 14.2 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Radical_SAM PF04055.21 KKK41489.1 - 5.5e-10 39.9 0.1 2.3e-09 37.9 0.1 2.0 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KKK41489.1 - 1.1e-05 25.6 0.1 7.7e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK41489.1 - 0.00035 20.8 0.6 0.0024 18.2 0.1 2.4 2 1 0 3 3 3 1 4Fe-4S single cluster domain DUF5637 PF18687.1 KKK41489.1 - 0.012 15.6 2.6 0.026 14.5 2.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5637) PALP PF00291.25 KKK41492.1 - 2.7e-08 33.6 0.0 2.9e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YkyA PF10368.9 KKK41493.1 - 0.022 14.5 0.3 0.035 13.8 0.3 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Flagellin_N PF00669.20 KKK41493.1 - 0.5 10.5 2.4 1.4 9.0 1.6 2.0 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region CheY-binding PF09078.11 KKK41493.1 - 0.99 9.6 2.6 29 4.9 0.2 2.5 1 1 1 2 2 2 0 CheY binding DUF948 PF06103.11 KKK41493.1 - 1.4 9.2 4.8 4.6 7.6 4.8 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DrsE PF02635.15 KKK41494.1 - 5.5e-07 30.0 0.0 6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 KKK41494.1 - 7.4e-05 22.7 0.1 7.5e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 DsrE/DsrF/DrsH-like family NMT1_2 PF13379.6 KKK41495.1 - 2.6e-14 53.5 0.0 3.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 KKK41495.1 - 2.9e-06 27.4 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like DUF3834 PF12916.7 KKK41495.1 - 0.076 12.3 0.3 10 5.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) DUF4023 PF13215.6 KKK41495.1 - 0.78 9.8 3.9 67 3.6 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4023) GDC-P PF02347.16 KKK41498.1 - 3.9e-80 269.8 0.1 4.3e-80 269.7 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein PRK PF00485.18 KKK41498.1 - 0.00089 19.1 0.1 0.0013 18.5 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family GCV_H PF01597.19 KKK41499.1 - 4.6e-41 139.5 1.2 5.4e-41 139.3 1.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein GCV_T PF01571.21 KKK41500.1 - 4.2e-86 288.5 0.0 5e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KKK41500.1 - 2.6e-23 81.7 0.0 4.3e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain POPLD PF08170.12 KKK41500.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 POPLD (NUC188) domain GTP_EFTU_D4 PF14578.6 KKK41500.1 - 0.21 11.5 1.6 15 5.5 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 IncD PF17628.2 KKK41503.1 - 1.3 8.8 4.4 0.71 9.7 2.1 1.7 1 1 0 1 1 1 0 Inclusion membrane protein D CPBP PF02517.16 KKK41503.1 - 8.6 6.8 18.8 4 7.9 13.2 2.8 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease Arf PF00025.21 KKK41504.1 - 1.3e-07 31.3 1.1 2.4e-07 30.4 1.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK41504.1 - 0.00038 20.1 0.2 0.0025 17.4 0.1 2.2 2 0 0 2 2 2 1 Ras family G-alpha PF00503.20 KKK41504.1 - 0.0005 19.3 0.7 0.00076 18.7 0.7 1.3 1 0 0 1 1 1 1 G-protein alpha subunit DrrA_P4M PF14860.6 KKK41504.1 - 0.0092 15.8 4.8 0.11 12.4 0.4 2.9 2 1 1 3 3 3 2 DrrA phosphatidylinositol 4-phosphate binding domain DUF4199 PF13858.6 KKK41505.1 - 0.24 11.8 19.4 0.81 10.1 19.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DHHC PF01529.20 KKK41505.1 - 0.4 10.8 12.6 1.8 8.7 12.5 1.9 1 1 0 1 1 1 0 DHHC palmitoyltransferase Anoctamin PF04547.12 KKK41505.1 - 0.86 8.4 8.0 1 8.1 8.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel SUR7 PF06687.12 KKK41505.1 - 4.2 6.9 13.0 0.08 12.6 5.3 1.6 1 1 0 1 1 1 0 SUR7/PalI family Glycos_transf_3 PF00591.21 KKK41506.1 - 1.8e-88 296.4 0.7 9e-88 294.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KKK41506.1 - 2e-20 72.4 2.1 2e-20 72.4 2.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain DUF2922 PF11148.8 KKK41506.1 - 0.093 12.5 0.4 0.45 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) IGPS PF00218.21 KKK41507.1 - 2.8e-60 203.6 1.1 3.3e-60 203.4 1.1 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 KKK41507.1 - 0.018 14.1 0.0 0.098 11.7 0.0 1.9 1 1 0 1 1 1 0 FMN-dependent dehydrogenase ThiG PF05690.14 KKK41507.1 - 0.066 12.5 0.3 4.5 6.5 0.1 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PRAI PF00697.22 KKK41508.1 - 8.8e-33 113.7 0.2 9.9e-33 113.5 0.2 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase MSP1b PF03429.13 KKK41508.1 - 0.014 13.5 0.1 0.02 13.1 0.1 1.1 1 0 0 1 1 1 0 Major surface protein 1B TMP-TENI PF02581.17 KKK41508.1 - 0.11 11.8 0.3 0.47 9.8 0.1 2.2 1 1 0 1 1 1 0 Thiamine monophosphate synthase QRPTase_C PF01729.19 KKK41508.1 - 0.15 11.8 0.7 0.21 11.4 0.1 1.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PALP PF00291.25 KKK41509.1 - 3e-42 145.1 0.0 3.8e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.20 KKK41510.1 - 2.9e-80 268.9 1.3 3.3e-80 268.7 1.3 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 KKK41510.1 - 4.4e-07 29.6 0.3 2.9e-06 26.9 0.2 2.1 2 1 0 2 2 2 1 Histidine biosynthesis protein PcrB PF01884.17 KKK41510.1 - 9.9e-05 21.9 1.4 0.00058 19.4 0.4 2.2 1 1 1 2 2 2 1 PcrB family FMN_dh PF01070.18 KKK41510.1 - 0.00072 18.7 0.9 0.046 12.7 0.1 2.7 2 1 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 KKK41510.1 - 0.00078 18.8 0.2 0.0014 17.9 0.2 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 KKK41510.1 - 0.0023 17.1 2.1 0.009 15.2 1.9 2.4 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Ribul_P_3_epim PF00834.19 KKK41510.1 - 0.0027 17.1 2.0 0.0039 16.6 0.3 2.2 2 1 1 3 3 3 1 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.21 KKK41510.1 - 0.011 15.0 4.4 0.68 9.1 4.4 2.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase OMPdecase PF00215.24 KKK41510.1 - 0.014 15.0 1.4 6.1 6.4 0.5 2.9 1 1 3 4 4 4 0 Orotidine 5'-phosphate decarboxylase / HUMPS family IMPDH PF00478.25 KKK41510.1 - 0.039 12.9 0.7 0.081 11.9 0.2 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KKK41510.1 - 0.049 13.0 0.8 0.45 9.8 0.1 2.0 1 1 1 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.17 KKK41510.1 - 0.1 12.0 1.0 0.23 10.8 0.2 2.1 3 0 0 3 3 3 0 Thiamine monophosphate synthase DUF3502 PF12010.8 KKK41510.1 - 0.12 13.0 0.0 0.81 10.3 0.0 2.2 2 1 0 3 3 3 0 Domain of unknown function (DUF3502) Methyltransf_11 PF08241.12 KKK41511.1 - 9.4e-20 71.1 0.1 2.8e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK41511.1 - 2.8e-19 69.6 0.1 7.9e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK41511.1 - 1.3e-16 60.7 0.1 1.8e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK41511.1 - 4.1e-14 53.1 0.2 5.3e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK41511.1 - 2.6e-12 46.9 0.0 3.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK41511.1 - 2.5e-11 43.3 0.0 3.5e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KKK41511.1 - 5.9e-07 29.3 0.0 8.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 KKK41511.1 - 4.6e-06 26.3 0.0 8.7e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 KKK41511.1 - 6.8e-06 25.4 0.0 8.8e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 KKK41511.1 - 1.4e-05 24.7 0.2 2.6e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KKK41511.1 - 2.7e-05 24.0 0.0 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 KKK41511.1 - 4.5e-05 23.1 0.0 6.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.15 KKK41511.1 - 5.9e-05 23.0 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 KKK41511.1 - 0.00055 19.1 0.1 0.00068 18.8 0.1 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_33 PF10017.9 KKK41511.1 - 0.00065 18.9 0.1 0.0024 17.1 0.0 1.8 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_18 PF12847.7 KKK41511.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KKK41511.1 - 0.013 15.0 0.0 0.045 13.2 0.0 1.9 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain TPMT PF05724.11 KKK41511.1 - 0.021 14.5 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_15 PF09445.10 KKK41511.1 - 0.022 14.3 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KKK41511.1 - 0.022 14.1 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KKK41511.1 - 0.033 13.6 0.3 0.054 12.9 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.6 KKK41511.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.10 KKK41511.1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Chorismate_bind PF00425.18 KKK41512.1 - 3.2e-85 285.8 0.1 1.4e-84 283.7 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KKK41512.1 - 7.4e-16 58.7 1.5 3.6e-14 53.2 0.3 2.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region RbcS PF12338.8 KKK41512.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit GATase PF00117.28 KKK41513.1 - 1.3e-49 168.5 0.0 1.5e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKK41513.1 - 5.4e-14 52.5 0.0 7.8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 Fer4_7 PF12838.7 KKK41514.1 - 1.8e-05 25.2 4.2 0.0029 18.2 0.2 2.8 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41514.1 - 4e-05 23.7 4.1 0.0073 16.5 1.7 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41514.1 - 0.00037 20.2 2.6 0.00037 20.2 2.6 3.5 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_16 PF13484.6 KKK41514.1 - 0.0014 19.5 15.5 0.0065 17.4 12.0 2.7 2 1 1 3 3 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK41514.1 - 0.0024 18.0 11.2 0.016 15.3 4.0 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK41514.1 - 0.0076 16.7 4.0 0.49 10.9 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK41514.1 - 0.014 15.6 2.9 4.4 7.5 2.7 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41514.1 - 0.044 13.9 9.1 0.12 12.5 1.1 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41514.1 - 0.079 13.5 8.8 0.42 11.2 2.7 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_19 PF06902.11 KKK41514.1 - 0.096 12.8 4.0 0.51 10.4 0.2 3.1 3 0 0 3 3 3 0 Divergent 4Fe-4S mono-cluster Fer4_2 PF12797.7 KKK41514.1 - 2.5 8.4 13.7 0.31 11.2 3.5 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK41514.1 - 6.7 7.9 20.1 3.7 8.7 1.1 3.7 4 0 0 4 4 3 0 4Fe-4S binding domain Response_reg PF00072.24 KKK41515.1 - 1.5e-06 28.4 0.1 1.6e-06 28.2 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PEPcase_2 PF14010.6 KKK41516.1 - 6.3e-189 628.6 0.4 7.1e-189 628.4 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase RcpB PF16971.5 KKK41516.1 - 0.0055 16.6 1.6 0.55 10.1 0.1 2.3 2 0 0 2 2 2 2 Rough colony protein B, tight adherence - tad - subunit PEPcase PF00311.17 KKK41516.1 - 0.073 11.1 0.0 0.13 10.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Mntp PF02659.15 KKK41517.1 - 1.8e-50 170.7 23.7 3.5e-50 169.7 13.6 2.0 1 1 1 2 2 2 2 Putative manganese efflux pump FtsX PF02687.21 KKK41518.1 - 0.031 14.8 0.1 0.034 14.6 0.1 1.2 1 0 0 1 1 1 0 FtsX-like permease family PAS_4 PF08448.10 KKK41519.1 - 1.3e-08 35.1 0.0 9.1e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKK41519.1 - 1.9e-08 34.5 0.0 0.0062 16.8 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 KKK41519.1 - 6.3e-05 22.9 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KKK41519.1 - 0.0022 18.0 0.0 0.008 16.2 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KKK41519.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold ATP-synt_F PF01990.17 KKK41519.1 - 0.059 13.7 0.3 0.097 13.0 0.3 1.3 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit RMI1_N PF08585.12 KKK41522.1 - 0.1 12.3 1.9 1.9 8.2 0.1 2.3 1 1 1 2 2 2 0 RecQ mediated genome instability protein DegS PF05384.11 KKK41522.1 - 0.9 9.0 9.2 1.4 8.4 2.0 2.9 3 0 0 3 3 3 0 Sensor protein DegS SMC_N PF02463.19 KKK41523.1 - 3.3e-25 88.8 36.7 1.4e-15 57.3 6.7 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK41523.1 - 1.2e-14 55.3 15.8 1.2e-14 55.3 15.8 6.7 2 2 4 6 6 6 1 AAA domain AAA_27 PF13514.6 KKK41523.1 - 0.00012 21.7 3.7 0.00018 21.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain SMC_hinge PF06470.13 KKK41523.1 - 0.00015 22.0 0.8 0.00047 20.5 0.1 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 KKK41523.1 - 0.0015 18.2 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KKK41523.1 - 0.0032 17.3 56.2 0.0032 17.3 56.2 4.9 1 1 1 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 KKK41523.1 - 0.0035 17.5 0.0 0.0088 16.3 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF3755 PF12579.8 KKK41523.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) ABC_tran PF00005.27 KKK41523.1 - 4.9 7.7 0.0 4.9 7.7 0.0 5.8 3 2 1 4 4 4 0 ABC transporter SRF-TF PF00319.18 KKK41524.1 - 0.069 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF4379 PF14311.6 KKK41525.1 - 1e-16 61.0 17.9 0.00013 22.2 0.4 4.4 4 0 0 4 4 4 4 Probable Zinc-ribbon domain zf-RING_4 PF14570.6 KKK41525.1 - 0.0018 18.1 17.0 0.56 10.0 0.3 4.5 4 0 0 4 4 4 2 RING/Ubox like zinc-binding domain CpXC PF14353.6 KKK41525.1 - 0.027 14.5 0.7 32 4.6 0.0 4.0 4 0 0 4 4 4 0 CpXC protein GIT_CC PF16559.5 KKK41525.1 - 0.041 13.8 0.1 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor EF-hand_7 PF13499.6 KKK41525.1 - 0.051 14.0 0.1 0.15 12.5 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair zf-3CxxC_2 PF17180.4 KKK41525.1 - 0.064 14.0 14.1 1.3 9.8 0.4 4.2 4 0 0 4 4 4 0 Zinc-binding domain NDUF_B7 PF05676.13 KKK41525.1 - 0.068 12.9 8.3 0.62 9.8 0.0 4.8 5 0 0 5 5 5 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3585 PF12130.8 KKK41525.1 - 0.081 13.1 0.3 4.8 7.3 0.1 2.7 2 1 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain EF-hand_2 PF09068.11 KKK41525.1 - 0.092 12.9 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 EF hand zf-Di19 PF05605.12 KKK41525.1 - 0.56 10.6 5.0 1.3 9.4 0.0 3.4 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 KKK41525.1 - 0.9 9.7 11.3 18 5.5 0.2 4.4 4 0 0 4 4 4 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 KKK41525.1 - 1.4 8.9 10.5 30 4.6 0.3 4.3 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Anti-TRAP PF15777.5 KKK41525.1 - 1.4 8.9 7.2 2.3 8.3 0.0 3.7 4 0 0 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-trcl PF13451.6 KKK41525.1 - 2 8.4 7.9 6.5 6.7 1.0 3.4 3 0 0 3 3 3 0 Probable zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK41525.1 - 3.1 8.6 11.1 24 5.7 0.1 4.4 3 2 0 3 3 3 0 zinc-ribbon family Tmemb_55A PF09788.9 KKK41525.1 - 3.3 6.7 8.2 6.9 5.7 0.2 3.3 2 1 1 3 3 3 0 Transmembrane protein 55A zf-TFIIB PF13453.6 KKK41525.1 - 5.4 6.4 8.1 33 3.9 0.1 4.0 4 0 0 4 4 4 0 Transcription factor zinc-finger HALZ PF02183.18 KKK41528.1 - 0.016 15.4 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF1801 PF08818.11 KKK41528.1 - 0.028 14.9 0.2 0.22 12.1 0.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DU1801) CENP-F_leu_zip PF10473.9 KKK41528.1 - 0.23 11.5 4.2 0.57 10.2 1.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSP20 PF00011.21 KKK41529.1 - 8.6e-09 35.5 2.4 1.3e-07 31.7 0.4 2.4 2 1 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKK41529.1 - 4.1e-06 26.3 0.2 3e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Pectinesterase PF01095.19 KKK41529.1 - 0.12 11.1 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Pectinesterase HATPase_c PF02518.26 KKK41530.1 - 4.8e-15 56.0 0.5 4.8e-15 56.0 0.5 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK41530.1 - 4e-05 23.6 0.3 0.00011 22.2 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KKK41530.1 - 0.00083 19.3 0.1 0.0026 17.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 KKK41530.1 - 0.0098 15.8 3.3 0.0098 15.8 3.3 2.3 1 1 1 2 2 2 1 GHKL domain EMC3_TMCO1 PF01956.16 KKK41530.1 - 0.73 9.5 6.1 0.12 12.0 0.4 2.7 2 1 1 3 3 3 0 Integral membrane protein EMC3/TMCO1-like ApoO PF09769.9 KKK41530.1 - 2.3 8.2 4.0 2.3 8.2 0.8 2.6 2 1 0 2 2 2 0 Apolipoprotein O TPP_enzyme_C PF02775.21 KKK41531.1 - 2.4e-25 89.1 0.1 1.4e-24 86.6 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 KKK41531.1 - 9.4e-13 48.4 0.1 2.1e-12 47.3 0.1 1.6 1 1 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fer4_10 PF13237.6 KKK41531.1 - 0.00012 22.1 9.1 0.007 16.4 9.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41531.1 - 0.00033 20.4 9.2 0.0016 18.2 3.1 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 KKK41531.1 - 0.00036 20.5 11.5 0.039 14.0 1.6 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK41531.1 - 0.0006 20.4 5.0 0.0018 18.8 4.9 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41531.1 - 0.0019 18.3 3.8 0.0049 17.0 3.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41531.1 - 0.0028 17.8 6.0 0.0066 16.6 6.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41531.1 - 0.0039 17.2 1.6 0.0039 17.2 1.6 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain DXP_synthase_N PF13292.6 KKK41531.1 - 0.03 13.5 0.6 0.068 12.4 0.6 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 KKK41531.1 - 0.1 12.3 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Fer4_8 PF13183.6 KKK41531.1 - 0.18 12.3 6.2 0.37 11.3 6.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41531.1 - 0.66 10.6 7.1 2.5 8.7 7.2 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK41531.1 - 4.7 8.2 8.4 19 6.3 7.4 2.4 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK41531.1 - 9.1 7.1 11.2 1.6 9.4 2.2 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain POR PF01558.18 KKK41532.1 - 2.2e-32 112.5 0.0 2.7e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Lactamase_B PF00753.27 KKK41533.1 - 1.6e-18 67.4 0.0 2.4e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK41533.1 - 1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KKK41533.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain RNA_pol_Rpb1_5 PF04998.17 KKK41536.1 - 3.7e-13 49.5 0.1 4e-13 49.4 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_5 PF04998.17 KKK41537.1 - 2.6e-51 174.6 0.5 3.9e-51 174.1 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 DUF1160 PF06648.11 KKK41537.1 - 0.056 13.4 0.2 0.056 13.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) Ribosomal_L7Ae PF01248.26 KKK41538.1 - 1.4e-13 50.4 0.0 2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family KH_2 PF07650.17 KKK41539.1 - 8.7e-14 51.1 9.0 1.7e-07 31.0 3.5 2.4 2 1 0 2 2 2 2 KH domain KH_5 PF13184.6 KKK41539.1 - 9.6e-14 51.2 6.7 2.7e-11 43.4 1.4 2.3 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 KKK41539.1 - 1e-10 41.3 1.9 1.1e-05 25.2 0.5 2.3 2 0 0 2 2 2 2 KH domain KH_1 PF00013.29 KKK41539.1 - 5.1e-06 26.2 7.5 0.0097 15.7 1.5 2.8 1 1 1 2 2 2 2 KH domain Peptidase_M28 PF04389.17 KKK41540.1 - 6.2e-21 75.0 0.0 6.4e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 Peptidase_M42 PF05343.14 KKK41540.1 - 5.7e-05 22.3 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KKK41540.1 - 0.075 12.7 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Ribosom_S12_S23 PF00164.25 KKK41541.1 - 1.7e-47 159.8 1.1 2.2e-47 159.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.21 KKK41542.1 - 4.8e-31 107.4 0.3 5.9e-31 107.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SdpI PF13630.6 KKK41547.1 - 0.0037 17.4 2.6 0.0037 17.4 2.6 2.2 3 0 0 3 3 3 1 SdpI/YhfL protein family CECR6_TMEM121 PF14997.6 KKK41547.1 - 0.0041 17.0 0.5 0.0068 16.3 0.0 1.6 2 0 0 2 2 2 1 CECR6/TMEM121 family DUF2157 PF09925.9 KKK41547.1 - 0.0051 16.6 3.1 0.025 14.4 3.0 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 KKK41547.1 - 0.0098 15.6 1.5 0.26 10.9 1.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4131) LptF_LptG PF03739.14 KKK41547.1 - 0.012 14.5 8.1 0.019 13.8 8.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG PMP22_Claudin PF00822.20 KKK41547.1 - 0.02 14.8 0.2 0.035 14.0 0.2 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Cpta_toxin PF07254.12 KKK41547.1 - 0.077 13.0 1.2 0.14 12.2 0.9 1.6 1 1 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system MFS_MOT1 PF16983.5 KKK41547.1 - 0.085 13.3 0.2 0.22 11.9 0.1 1.8 1 1 0 1 1 1 0 Molybdate transporter of MFS superfamily DUF2207 PF09972.9 KKK41547.1 - 0.7 8.6 11.9 1.2 7.8 9.7 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) UPF0370 PF13980.6 KKK41547.1 - 0.78 9.8 4.0 1.5 8.9 3.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0370) DUF5518 PF17647.1 KKK41547.1 - 1.4 9.1 10.0 0.098 12.8 4.9 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5518) VIT1 PF01988.19 KKK41547.1 - 2.4 7.9 6.6 2.4 8.0 2.4 2.3 1 1 2 3 3 3 0 VIT family Robl_LC7 PF03259.17 KKK41548.1 - 6.2e-20 70.8 0.2 7.3e-20 70.5 0.2 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF2207 PF09972.9 KKK41548.1 - 0.06 12.1 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YCII PF03795.14 KKK41550.1 - 3.7e-11 43.3 0.0 4.2e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Spt5-NGN PF03439.13 KKK41550.1 - 0.007 16.2 0.0 0.0096 15.8 0.0 1.2 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DeoC PF01791.9 KKK41551.1 - 5.2e-47 160.4 0.0 6.1e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase OMPdecase PF00215.24 KKK41551.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family AP_endonuc_2 PF01261.24 KKK41551.1 - 0.0071 15.8 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel S1 PF00575.23 KKK41552.1 - 4.2e-13 49.4 0.5 1.3e-12 47.9 0.5 1.9 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 KKK41552.1 - 5.3e-13 49.1 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Spt4 PF06093.13 KKK41553.1 - 9.6e-14 51.2 0.1 1.3e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RecR PF02132.15 KKK41553.1 - 0.063 12.9 3.5 0.091 12.3 3.5 1.3 1 0 0 1 1 1 0 RecR protein MCR PF18509.1 KKK41553.1 - 0.12 11.9 0.3 0.12 11.9 0.3 1.7 2 0 0 2 2 2 0 Magnetochrome domain PolC_DP2 PF03833.13 KKK41553.1 - 0.13 10.1 0.4 0.12 10.2 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_4 PF14570.6 KKK41553.1 - 0.15 11.8 3.7 0.24 11.2 3.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C4H2 PF10146.9 KKK41553.1 - 0.18 12.1 3.1 0.21 11.8 3.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2367 PF10164.9 KKK41553.1 - 0.22 12.1 2.9 0.6 10.6 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2367) TF_Zn_Ribbon PF08271.12 KKK41553.1 - 0.35 10.4 4.5 2.9 7.5 4.7 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KKK41553.1 - 0.55 9.7 6.1 0.41 10.1 0.4 2.0 1 1 0 2 2 2 0 zinc-ribbon domain DUF359 PF04019.12 KKK41554.1 - 8.1e-22 77.2 0.2 1.6e-21 76.2 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF359) Ribosomal_S24e PF01282.19 KKK41555.1 - 3.7e-18 65.2 0.1 5.1e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S27 PF01599.19 KKK41556.1 - 6.7e-19 67.8 2.1 8.9e-19 67.4 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S27a Ribosomal_L37e PF01907.19 KKK41556.1 - 0.0006 19.9 3.9 0.00088 19.4 3.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zf-HYPF PF07503.12 KKK41556.1 - 0.0037 17.0 2.9 0.094 12.5 0.3 2.3 2 0 0 2 2 2 1 HypF finger Zn_Tnp_IS1595 PF12760.7 KKK41556.1 - 0.0088 16.0 2.9 0.013 15.5 2.9 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf_C2H2_10 PF18414.1 KKK41556.1 - 0.022 14.3 3.8 3.7 7.2 1.5 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger GFA PF04828.14 KKK41556.1 - 0.025 14.9 2.0 1.7 9.1 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.12 KKK41556.1 - 0.036 13.6 1.3 0.063 12.8 1.3 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 KKK41556.1 - 0.049 14.0 0.6 0.062 13.7 0.6 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar C1_1 PF00130.22 KKK41556.1 - 0.05 13.5 1.4 0.066 13.1 1.4 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.11 KKK41556.1 - 0.054 13.4 0.8 0.079 12.9 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2 PF00096.26 KKK41556.1 - 0.07 13.6 5.0 3.8 8.2 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2225 PF09986.9 KKK41556.1 - 0.074 12.8 1.2 0.16 11.6 1.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) ADK_lid PF05191.14 KKK41556.1 - 0.077 13.0 4.7 3.1 7.8 0.2 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid FYDLN_acid PF09538.10 KKK41556.1 - 0.11 13.2 1.7 0.13 12.9 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1451 PF07295.11 KKK41556.1 - 0.19 11.8 0.7 0.22 11.6 0.7 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-NADH-PPase PF09297.11 KKK41556.1 - 0.3 10.8 7.6 2.2 8.0 1.5 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_13 PF09855.9 KKK41556.1 - 0.37 11.0 4.0 0.75 10.0 0.2 2.2 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zinc_ribbon_5 PF13719.6 KKK41556.1 - 0.53 10.1 3.8 3.9 7.3 3.8 2.2 1 1 0 1 1 1 0 zinc-ribbon domain NADH_4Fe-4S PF10589.9 KKK41556.1 - 1 9.5 3.7 3.5 7.8 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region zf-ribbon_3 PF13248.6 KKK41556.1 - 1.9 8.0 6.8 1.3 8.5 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_M22 PF00814.25 KKK41557.1 - 4.8e-80 269.2 0.0 5.9e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.20 KKK41557.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Pkinase PF00069.25 KKK41558.1 - 4.2e-11 42.7 0.4 6.3e-11 42.1 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KKK41558.1 - 4.6e-11 42.7 0.0 7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KKK41558.1 - 2.8e-09 36.7 0.0 4.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK41558.1 - 8.9e-07 28.5 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK41558.1 - 2.7e-06 27.5 0.0 0.0004 20.4 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK41558.1 - 0.012 14.4 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase RHH_1 PF01402.21 KKK41559.1 - 2.2e-06 27.4 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family VapB_antitoxin PF09957.9 KKK41559.1 - 0.0055 16.6 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB RHH_8 PF17723.1 KKK41559.1 - 0.13 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family Gelsolin PF00626.22 KKK41560.1 - 3.3e-14 52.6 0.0 7.4e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Phage_Arf PF17585.2 KKK41560.1 - 0.084 12.8 0.6 0.16 11.9 0.6 1.5 1 0 0 1 1 1 0 Accessory recombination function protein Ribosomal_S28e PF01200.18 KKK41561.1 - 1.7e-28 98.4 2.0 2.4e-28 97.9 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L7Ae PF01248.26 KKK41562.1 - 2.3e-21 75.3 0.1 2.9e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1694 PF07997.11 KKK41562.1 - 0.021 14.9 0.1 0.026 14.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Dehydratase_MU PF02288.15 KKK41562.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Dehydratase medium subunit RNase_P_pop3 PF08228.11 KKK41562.1 - 0.042 13.9 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 DUF3671 PF12420.8 KKK41565.1 - 0.066 13.3 7.3 0.17 11.9 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function adh_short PF00106.25 KKK41567.1 - 4.7e-18 65.3 0.0 7.2e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK41567.1 - 2e-13 50.4 0.0 3.9e-13 49.5 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AsnC_trans_reg PF01037.21 KKK41568.1 - 0.0029 17.5 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain LPD25 PF18840.1 KKK41572.1 - 0.67 10.5 6.8 2.6 8.7 0.8 2.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 25 Hist_deacetyl PF00850.19 KKK41573.1 - 6.5e-77 259.0 0.0 7.8e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain AsiA PF09010.10 KKK41573.1 - 0.071 13.2 0.0 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Anti-Sigma Factor A dsDNA_bind PF01984.20 KKK41575.1 - 0.0044 17.3 7.1 0.012 15.9 0.9 2.1 1 1 1 2 2 2 2 Double-stranded DNA-binding domain LMBR1 PF04791.16 KKK41575.1 - 0.34 9.8 1.8 0.36 9.7 1.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein UQ_con PF00179.26 KKK41576.1 - 5.8e-20 71.4 0.0 7.3e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK41576.1 - 0.052 13.8 1.1 0.06 13.6 1.0 1.5 1 1 0 1 1 1 0 RWD domain DUF3160 PF11369.8 KKK41578.1 - 0.099 11.1 0.4 0.14 10.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) PDE4_UCR PF18100.1 KKK41579.1 - 0.058 14.0 0.4 0.1 13.3 0.4 1.4 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF4119 PF13494.6 KKK41579.1 - 0.32 11.1 8.6 0.13 12.4 5.5 1.8 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) RXLR PF16810.5 KKK41579.1 - 0.54 10.7 6.6 0.8 10.1 6.6 1.6 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity T5orf172 PF10544.9 KKK41580.1 - 8.1e-09 36.0 0.1 1.7e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KKK41580.1 - 2.6e-08 34.4 0.2 5.8e-08 33.3 0.2 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 GIY-YIG PF01541.24 KKK41580.1 - 0.054 13.8 2.7 0.13 12.5 0.7 2.6 2 1 0 2 2 2 0 GIY-YIG catalytic domain SNase PF00565.17 KKK41582.1 - 2.6e-09 37.5 0.0 3.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Y_Y_Y PF07495.13 KKK41583.1 - 0.00012 22.0 4.2 0.023 14.6 0.3 2.4 2 0 0 2 2 2 2 Y_Y_Y domain hGDE_N PF14699.6 KKK41583.1 - 0.0014 18.7 0.7 1.1 9.5 0.1 2.9 1 1 1 2 2 2 2 N-terminal domain from the human glycogen debranching enzyme ChitinaseA_N PF08329.10 KKK41583.1 - 0.0023 17.6 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Chitinase A, N-terminal domain DUF2691 PF10903.8 KKK41583.1 - 0.031 14.1 2.5 2.3 8.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2691) FOG_N PF15888.5 KKK41583.1 - 0.042 14.2 1.0 0.46 10.9 0.4 2.1 2 0 0 2 2 2 0 Folded gastrulation N-terminus ATP-synt_ab PF00006.25 KKK41589.1 - 7.3e-64 215.3 0.0 9.1e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF2695 PF10905.8 KKK41590.1 - 7.9e-07 29.2 2.1 1.7e-06 28.1 2.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2695) Peptidase_C25 PF01364.18 KKK41592.1 - 6.7e-22 78.2 0.9 8.2e-22 77.9 0.9 1.0 1 0 0 1 1 1 1 Peptidase family C25 EptA_B_N PF08019.12 KKK41592.1 - 0.084 12.8 1.1 0.15 12.0 1.1 1.3 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB ATP-synt_D PF01813.17 KKK41593.1 - 4.8e-32 111.4 8.7 5.4e-32 111.2 8.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit D DUF2397 PF09660.10 KKK41593.1 - 0.17 10.7 0.3 0.24 10.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) V_ATPase_I PF01496.19 KKK41594.1 - 6.7e-43 146.7 20.8 4.9e-24 84.3 9.2 4.0 2 1 0 2 2 2 2 V-type ATPase 116kDa subunit family zinc_ribbon_2 PF13240.6 KKK41595.1 - 0.0025 17.5 7.3 0.0037 16.9 7.3 1.2 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK41595.1 - 0.0047 17.6 0.4 0.0047 17.6 0.4 1.6 2 0 0 2 2 2 1 zinc-ribbon family TspO_MBR PF03073.15 KKK41595.1 - 0.02 14.9 0.7 0.029 14.4 0.7 1.1 1 0 0 1 1 1 0 TspO/MBR family DUF2207 PF09972.9 KKK41595.1 - 0.023 13.5 0.9 0.028 13.2 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-ribbon_3 PF13248.6 KKK41595.1 - 0.023 14.1 4.2 0.042 13.3 4.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain EXS PF03124.14 KKK41595.1 - 0.024 14.0 0.7 0.027 13.8 0.7 1.1 1 0 0 1 1 1 0 EXS family HypA PF01155.19 KKK41595.1 - 0.038 14.0 0.1 0.047 13.7 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Wzy_C PF04932.15 KKK41595.1 - 0.043 13.4 0.3 0.05 13.2 0.3 1.2 1 0 0 1 1 1 0 O-Antigen ligase E1-E2_ATPase PF00122.20 KKK41595.1 - 0.054 13.0 1.6 0.075 12.6 1.6 1.1 1 0 0 1 1 1 0 E1-E2 ATPase zf-C2HC5 PF06221.13 KKK41595.1 - 0.056 13.4 2.2 0.093 12.7 2.2 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF3043 PF11241.8 KKK41595.1 - 0.07 13.2 2.1 0.089 12.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) UPF0547 PF10571.9 KKK41595.1 - 0.088 12.9 2.1 0.15 12.2 2.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.6 KKK41595.1 - 0.096 12.6 0.9 0.14 12.0 0.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FUSC PF04632.12 KKK41595.1 - 0.21 10.1 0.2 0.24 9.9 0.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family RecR PF02132.15 KKK41595.1 - 0.49 10.0 2.4 1.1 8.9 2.4 1.5 1 1 0 1 1 1 0 RecR protein Ac76 PF05814.11 KKK41595.1 - 1 9.4 11.7 1.4 9.0 1.8 2.4 1 1 1 2 2 2 0 Orf76 (Ac76) Desulfoferrod_N PF06397.12 KKK41595.1 - 4.9 6.8 5.7 2.4 7.8 0.8 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain ATP-synt_ab PF00006.25 KKK41596.1 - 1.5e-84 282.9 0.0 2e-84 282.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KKK41596.1 - 1.8e-40 137.6 0.0 3.2e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KKK41596.1 - 1.8e-05 25.2 0.0 4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Med31 PF05669.12 KKK41597.1 - 0.036 14.1 0.1 0.057 13.4 0.1 1.3 1 0 0 1 1 1 0 SOH1 LRR_8 PF13855.6 KKK41598.1 - 9.2e-09 34.9 3.8 0.00018 21.2 1.4 3.8 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KKK41598.1 - 6.3e-06 26.5 8.9 0.012 16.0 1.9 4.4 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) DDE_Tnp_1 PF01609.21 KKK41599.1 - 1e-05 25.3 4.0 0.00022 20.9 4.0 2.2 1 1 0 1 1 1 1 Transposase DDE domain CPSase_L_D2 PF02786.17 KKK41601.1 - 2.5e-28 99.0 0.2 6.5e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain MGS PF02142.22 KKK41601.1 - 6e-20 71.2 0.7 1.9e-19 69.7 0.1 2.1 2 1 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.6 KKK41601.1 - 1.7e-07 31.0 0.1 5.5e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 KKK41601.1 - 6.8e-05 22.5 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KKK41601.1 - 0.0037 17.3 0.1 0.006 16.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KKK41601.1 - 0.038 13.6 0.1 0.083 12.5 0.1 1.6 1 1 0 1 1 1 0 RimK-like ATP-grasp domain DUF613 PF04764.12 KKK41601.1 - 0.15 12.2 1.3 8.3 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF613) LRR_8 PF13855.6 KKK41603.1 - 6.6e-13 48.2 17.3 1.5e-08 34.3 4.3 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KKK41603.1 - 4.8e-11 42.7 14.4 2.2e-06 27.9 5.7 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK41603.1 - 0.00052 20.2 6.8 1.5 9.6 0.7 4.4 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 KKK41603.1 - 0.033 13.7 3.2 0.028 13.9 1.4 1.8 2 0 0 2 2 2 0 Leucine-rich repeat ABC_tran PF00005.27 KKK41604.1 - 2.3e-35 122.1 0.0 4.5e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKK41604.1 - 4.3e-25 88.9 15.2 6.9e-25 88.2 14.7 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region DUF87 PF01935.17 KKK41604.1 - 6.6e-05 23.1 0.3 0.00017 21.7 0.3 1.7 1 1 0 1 1 1 1 Helicase HerA, central domain SMC_N PF02463.19 KKK41604.1 - 0.00098 18.6 1.0 0.12 11.8 0.1 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK41604.1 - 0.0012 19.1 1.2 0.008 16.5 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KKK41604.1 - 0.0021 18.6 0.0 0.0049 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKK41604.1 - 0.0029 16.7 0.4 0.0093 15.1 0.1 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein CbiA PF01656.23 KKK41604.1 - 0.0073 16.4 0.0 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 KKK41604.1 - 0.014 15.1 0.3 0.046 13.5 0.3 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 KKK41604.1 - 0.019 15.3 0.4 0.051 14.0 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KKK41604.1 - 0.023 14.5 0.2 6.2 6.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein G-alpha PF00503.20 KKK41604.1 - 0.035 13.3 0.1 0.076 12.2 0.1 1.6 1 0 0 1 1 1 0 G-protein alpha subunit TrwB_AAD_bind PF10412.9 KKK41604.1 - 0.04 12.8 0.1 0.07 12.0 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 KKK41604.1 - 0.041 13.1 0.4 0.57 9.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 KKK41604.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KKK41604.1 - 0.045 13.7 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MetOD2 PF18548.1 KKK41604.1 - 0.055 13.6 0.3 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Metanogen output domain 2 AAA_29 PF13555.6 KKK41604.1 - 0.058 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KKK41604.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KKK41604.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_8 PF12780.7 KKK41604.1 - 0.074 12.4 0.5 0.52 9.6 0.0 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 SRP54 PF00448.22 KKK41604.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 KKK41604.1 - 0.094 12.6 1.2 0.93 9.4 0.2 2.3 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 KKK41604.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KKK41604.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 KKK41604.1 - 0.38 11.2 3.9 0.99 9.9 3.3 2.3 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 KKK41605.1 - 2.1e-39 135.8 21.7 3e-39 135.3 21.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK41605.1 - 2.3e-32 112.4 0.0 3.9e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK41605.1 - 4e-05 23.1 0.0 0.0096 15.4 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KKK41605.1 - 0.0015 18.7 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_10 PF12846.7 KKK41605.1 - 0.0042 16.1 0.0 0.0086 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Zeta_toxin PF06414.12 KKK41605.1 - 0.012 14.9 0.1 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 KKK41605.1 - 0.013 15.9 0.1 0.032 14.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KKK41605.1 - 0.022 15.2 0.0 0.18 12.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KKK41605.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 KKK41605.1 - 0.032 14.1 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK41605.1 - 0.034 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KKK41605.1 - 0.036 13.8 0.2 0.078 12.7 0.2 1.5 1 0 0 1 1 1 0 AAA ATPase domain CitMHS PF03600.16 KKK41605.1 - 0.042 13.0 6.1 0.058 12.6 6.1 1.2 1 0 0 1 1 1 0 Citrate transporter AAA_22 PF13401.6 KKK41605.1 - 0.059 13.6 0.1 0.21 11.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKK41605.1 - 0.073 13.6 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KKK41605.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KKK41605.1 - 0.098 12.4 0.1 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 KKK41605.1 - 0.13 12.2 0.1 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KKK41605.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PrgI PF12666.7 KKK41605.1 - 6.4 7.6 11.7 8.5 7.2 2.2 2.8 2 0 0 2 2 2 0 PrgI family protein DUF2304 PF10066.9 KKK41607.1 - 0.14 12.4 4.5 0.15 12.3 4.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) HATPase_c PF02518.26 KKK41609.1 - 1.1e-16 61.4 2.6 1.5e-16 60.9 1.6 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK41609.1 - 0.00038 20.3 5.9 0.00038 20.3 5.9 2.2 1 1 1 2 2 2 1 GHKL domain HisKA PF00512.25 KKK41609.1 - 0.0075 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Cation_efflux PF01545.21 KKK41609.1 - 0.0092 15.7 4.6 0.025 14.3 4.6 1.7 1 1 0 1 1 1 1 Cation efflux family HATPase_c_2 PF13581.6 KKK41609.1 - 0.013 15.5 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HisKA_7TM PF16927.5 KKK41609.1 - 0.017 15.2 4.8 0.035 14.1 4.8 1.4 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase ATP1G1_PLM_MAT8 PF02038.16 KKK41609.1 - 0.043 13.3 2.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family OAD_gamma PF04277.13 KKK41609.1 - 0.088 13.4 0.5 0.088 13.4 0.5 3.0 3 1 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF3244 PF11589.8 KKK41609.1 - 0.39 10.8 8.1 0.57 10.3 1.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3244) DUF4064 PF13273.6 KKK41609.1 - 0.53 10.6 9.9 1.9 8.8 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) EMP70 PF02990.16 KKK41609.1 - 3 6.4 11.9 0.16 10.6 6.4 1.5 2 0 0 2 2 2 0 Endomembrane protein 70 MerC PF03203.14 KKK41610.1 - 0.019 15.4 0.3 0.021 15.3 0.3 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein HTH_44 PF14641.6 KKK41610.1 - 0.054 13.9 0.5 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 NAD_synthase PF02540.17 KKK41611.1 - 1.9e-67 226.9 0.0 6.2e-67 225.2 0.0 1.7 2 0 0 2 2 2 1 NAD synthase CN_hydrolase PF00795.22 KKK41611.1 - 2.9e-23 82.5 0.0 4.5e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATP_bind_3 PF01171.20 KKK41611.1 - 0.057 13.2 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 PP-loop family QueC PF06508.13 KKK41611.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Gln-synt_C PF00120.24 KKK41612.1 - 1.3e-121 405.9 0.0 1.5e-121 405.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KKK41612.1 - 3.7e-27 93.9 0.0 1e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 KKK41612.1 - 0.05 13.4 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain AsnC_trans_reg PF01037.21 KKK41614.1 - 1.8e-15 56.6 0.0 2.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_11 PF08279.12 KKK41614.1 - 1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 HTH domain HTH_AsnC-type PF13404.6 KKK41614.1 - 1.6e-05 24.6 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK41614.1 - 0.00036 20.0 0.1 0.0013 18.3 0.1 1.9 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 KKK41614.1 - 0.0084 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_12 PF08461.10 KKK41614.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain LexA_DNA_bind PF01726.16 KKK41614.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain KfrA_N PF11740.8 KKK41614.1 - 0.026 15.2 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Fe_dep_repress PF01325.19 KKK41614.1 - 0.049 13.8 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 KKK41614.1 - 0.17 11.9 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Alkyl_sulf_dimr PF14863.6 KKK41615.1 - 1.8e-32 112.7 0.0 3.1e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KKK41615.1 - 2.8e-12 47.0 0.0 1.4e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK41615.1 - 6.7e-05 22.5 0.0 0.00017 21.2 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF2526 PF10735.9 KKK41615.1 - 0.18 12.0 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) DUF3477 PF11963.8 KKK41615.1 - 0.23 10.6 0.0 0.35 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) HATPase_c PF02518.26 KKK41616.1 - 1.9e-14 54.1 2.1 2.6e-13 50.4 0.2 2.3 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK41616.1 - 0.00015 21.6 4.3 0.017 15.0 4.3 2.8 1 1 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KKK41616.1 - 0.0015 18.5 0.0 0.098 12.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain CotJB PF12652.7 KKK41616.1 - 0.17 12.1 0.2 0.35 11.1 0.2 1.4 1 0 0 1 1 1 0 CotJB protein DUF2935 PF11155.8 KKK41616.1 - 1.2 9.5 10.1 8.1 6.8 4.1 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) HTH_24 PF13412.6 KKK41617.1 - 2.2e-12 46.3 0.6 3.8e-12 45.6 0.6 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK41617.1 - 3.4e-11 42.8 0.0 6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 KKK41617.1 - 0.0033 17.3 0.1 0.0084 16.0 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family AsnC_trans_reg PF01037.21 KKK41617.1 - 0.0038 17.2 0.1 0.0082 16.1 0.0 1.6 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain MarR PF01047.22 KKK41617.1 - 0.0047 16.8 0.1 0.0093 15.9 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 KKK41617.1 - 0.027 14.4 0.2 0.05 13.6 0.2 1.4 1 0 0 1 1 1 0 HTH domain TrmB PF01978.19 KKK41617.1 - 0.054 13.4 0.1 0.29 11.1 0.1 2.0 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 KKK41617.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HEAT_2 PF13646.6 KKK41618.1 - 0.014 15.7 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 HEAT repeats T4_baseplate PF12322.8 KKK41618.1 - 0.033 13.6 2.6 0.038 13.5 2.6 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein HEAT PF02985.22 KKK41618.1 - 0.036 14.3 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 HEAT repeat RICTOR_V PF14668.6 KKK41618.1 - 0.065 13.5 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Fer4_9 PF13187.6 KKK41619.1 - 4.8e-06 26.6 1.0 0.0031 17.6 0.2 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK41619.1 - 2.3e-05 24.9 4.1 0.0044 17.6 0.2 2.8 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41619.1 - 0.00027 20.6 2.1 0.00027 20.6 2.1 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 KKK41619.1 - 0.00046 20.1 2.6 0.00046 20.1 2.6 3.5 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_16 PF13484.6 KKK41619.1 - 0.00047 21.0 13.9 0.0013 19.6 10.4 2.7 2 1 1 3 3 2 2 4Fe-4S double cluster binding domain Fer4_19 PF06902.11 KKK41619.1 - 0.0027 17.8 0.3 0.089 12.9 0.1 2.8 3 0 0 3 3 2 1 Divergent 4Fe-4S mono-cluster Fer4_8 PF13183.6 KKK41619.1 - 0.0047 17.3 2.8 0.57 10.7 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK41619.1 - 0.019 15.2 3.6 1.7 8.9 2.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41619.1 - 0.055 14.0 7.9 0.37 11.4 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41619.1 - 0.062 13.4 9.3 0.52 10.5 2.2 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41619.1 - 0.083 13.0 16.1 0.047 13.8 11.6 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK41619.1 - 1.2 9.4 13.7 0.15 12.2 3.4 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK41619.1 - 3 9.0 19.3 1.8 9.7 3.5 3.7 4 0 0 4 4 3 0 4Fe-4S binding domain NTP_transf_2 PF01909.23 KKK41620.1 - 1e-12 48.2 0.8 1.4e-12 47.8 0.8 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KKK41620.1 - 2.2e-12 46.9 1.5 2.7e-12 46.6 1.5 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF86 PF01934.17 KKK41621.1 - 6.6e-25 87.3 0.3 7.6e-25 87.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF86 Flavodoxin_4 PF12682.7 KKK41621.1 - 0.068 12.9 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin RHH_1 PF01402.21 KKK41622.1 - 2.1e-05 24.3 1.4 0.0015 18.4 0.1 2.9 3 0 0 3 3 3 1 Ribbon-helix-helix protein, copG family UPF0175 PF03683.13 KKK41622.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0175) SIMPL PF04402.14 KKK41622.1 - 0.076 13.5 1.0 0.096 13.1 0.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF541) E1_UFD PF09358.10 KKK41622.1 - 0.1 13.3 0.1 0.26 12.0 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin fold domain ECH_1 PF00378.20 KKK41625.1 - 6.5e-14 51.8 0.0 7.5e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK41625.1 - 1.4e-13 51.1 0.0 1.6e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH_N PF02737.18 KKK41626.1 - 6.1e-53 179.4 0.0 8.5e-53 178.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK41626.1 - 1.6e-15 57.5 0.0 9.6e-11 42.2 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain THF_DHG_CYH_C PF02882.19 KKK41626.1 - 0.00085 18.7 1.0 0.17 11.2 0.1 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3479 PF11965.8 KKK41626.1 - 0.0029 17.7 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) NAD_Gly3P_dh_N PF01210.23 KKK41626.1 - 0.049 13.6 0.1 0.08 12.9 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NmrA PF05368.13 KKK41626.1 - 0.053 13.1 0.2 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KKK41626.1 - 0.13 11.8 0.5 0.23 11.0 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain COX5A PF02284.16 KKK41626.1 - 0.13 12.3 0.0 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va adh_short PF00106.25 KKK41626.1 - 0.14 11.6 0.4 0.25 10.8 0.3 1.5 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_2 PF03446.15 KKK41626.1 - 0.15 12.2 5.6 0.12 12.6 2.2 2.3 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 KKK41626.1 - 1.4 9.0 4.0 5.6 7.1 4.0 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus LMWPc PF01451.21 KKK41627.1 - 2.7e-25 89.4 0.0 3.1e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase LMWPc PF01451.21 KKK41628.1 - 5.1e-19 69.1 0.0 5.8e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MFS_2 PF13347.6 KKK41634.1 - 2.5e-07 29.6 1.6 3.1e-07 29.3 1.6 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein DIE2_ALG10 PF04922.12 KKK41634.1 - 0.43 9.8 8.4 1.3 8.2 2.8 2.1 1 1 0 2 2 2 0 DIE2/ALG10 family PALP PF00291.25 KKK41636.1 - 2.3e-57 194.7 0.0 3e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LDcluster4 PF18306.1 KKK41636.1 - 0.033 13.8 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 SLOG cluster4 family UPF0020 PF01170.18 KKK41636.1 - 0.041 13.6 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF2769 PF10967.8 KKK41637.1 - 1e-08 35.7 8.8 1.2e-08 35.4 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2769) ABC_tran PF00005.27 KKK41638.1 - 2.3e-34 118.8 0.2 3.5e-34 118.2 0.2 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKK41638.1 - 1.6e-13 51.0 1.4 2.5e-13 50.3 1.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF87 PF01935.17 KKK41638.1 - 0.00031 20.9 0.5 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain SMC_N PF02463.19 KKK41638.1 - 0.0026 17.2 5.9 0.085 12.3 5.8 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 KKK41638.1 - 0.014 14.5 0.2 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KKK41638.1 - 0.015 15.0 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.7 KKK41638.1 - 0.016 14.1 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 KKK41638.1 - 0.03 14.7 0.0 0.057 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KKK41638.1 - 0.035 14.0 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KKK41638.1 - 0.049 13.4 0.4 0.12 12.1 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 KKK41638.1 - 0.062 12.5 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KKK41638.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK41638.1 - 0.075 13.3 0.1 0.36 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK41638.1 - 0.08 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_membrane_3 PF13748.6 KKK41638.1 - 0.14 11.3 1.5 3 7.0 0.7 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region ABC_membrane PF00664.23 KKK41639.1 - 5.1e-39 134.6 20.1 8.2e-39 133.9 20.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK41639.1 - 4.6e-36 124.4 0.2 1e-35 123.2 0.2 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK41639.1 - 4e-05 23.2 0.1 0.0003 20.3 0.1 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KKK41639.1 - 0.0015 18.7 0.1 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 KKK41639.1 - 0.0028 17.5 3.0 0.098 12.4 0.1 2.9 2 2 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKK41639.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KKK41639.1 - 0.015 15.5 0.2 0.094 13.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KKK41639.1 - 0.022 14.8 0.2 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 KKK41639.1 - 0.027 13.6 0.1 0.077 12.1 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 KKK41639.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK41639.1 - 0.1 13.0 0.1 0.28 11.6 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KKK41639.1 - 0.1 13.1 0.1 0.61 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Synaptobrevin PF00957.21 KKK41639.1 - 0.78 9.6 0.0 0.78 9.6 0.0 2.6 2 0 0 2 2 1 0 Synaptobrevin HTH_5 PF01022.20 KKK41640.1 - 6e-13 48.4 0.5 1e-12 47.7 0.5 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KKK41640.1 - 2.5e-09 37.1 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KKK41640.1 - 0.012 15.1 0.4 0.039 13.5 0.2 2.0 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 KKK41640.1 - 0.018 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR_2 PF12802.7 KKK41640.1 - 0.086 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 MarR family SBF PF01758.16 KKK41641.1 - 1.1e-41 142.7 12.9 1.1e-41 142.7 12.9 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family Lactamase_B PF00753.27 KKK41643.1 - 3e-14 53.5 0.0 6.9e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK41643.1 - 0.0086 15.6 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain YdjM PF04307.14 KKK41646.1 - 1.8e-14 53.4 8.9 3e-14 52.7 8.9 1.4 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase ATPgrasp_TupA PF14305.6 KKK41646.1 - 0.038 13.8 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 TupA-like ATPgrasp HD PF01966.22 KKK41647.1 - 4.9e-14 52.6 3.6 7e-14 52.1 0.5 2.1 2 0 0 2 2 2 1 HD domain DUF4476 PF14771.6 KKK41647.1 - 0.063 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) DUF1029 PF06269.12 KKK41647.1 - 0.075 13.2 2.0 0.28 11.3 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1029) Lzipper-MIP1 PF14389.6 KKK41647.1 - 0.23 11.8 4.2 7.5 6.9 1.0 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF711 PF05167.12 KKK41649.1 - 2.8e-83 280.1 0.0 3.4e-83 279.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) Methyltransf_28 PF02636.17 KKK41649.1 - 0.2 11.2 0.1 5 6.7 0.0 2.1 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FlpD PF02662.16 KKK41650.1 - 1.3e-45 154.4 0.0 8.8e-45 151.7 0.0 2.5 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit Pyr_redox_2 PF07992.14 KKK41650.1 - 9.8e-20 71.0 0.0 2.7e-18 66.2 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.6 KKK41650.1 - 1.5e-08 34.6 31.0 0.0042 17.2 1.2 4.7 4 0 0 4 4 4 3 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK41650.1 - 8.7e-08 32.6 29.2 0.0012 19.3 9.7 4.4 2 2 4 6 6 6 6 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41650.1 - 2.2e-07 30.4 34.2 0.013 15.3 1.9 5.3 4 1 0 4 4 4 3 4Fe-4S binding domain Pyr_redox PF00070.27 KKK41650.1 - 8.4e-07 29.5 1.0 6.7e-06 26.6 1.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK41650.1 - 2.2e-06 27.8 0.2 4.7e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_6 PF12837.7 KKK41650.1 - 3.1e-06 27.0 29.7 0.012 15.7 0.9 4.8 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 KKK41650.1 - 6.9e-06 26.1 27.6 0.0031 17.6 8.4 3.6 3 1 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK41650.1 - 1.6e-05 24.7 37.2 0.084 13.0 1.2 5.2 5 0 0 5 5 4 4 4Fe-4S binding domain FAD_oxidored PF12831.7 KKK41650.1 - 3.2e-05 23.5 3.1 6e-05 22.6 3.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KKK41650.1 - 0.00013 21.2 0.4 0.00041 19.6 0.1 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KKK41650.1 - 0.00022 20.4 3.1 0.00042 19.5 3.1 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_10 PF13237.6 KKK41650.1 - 0.00031 20.8 33.9 0.0092 16.1 9.0 3.8 3 1 1 4 4 3 3 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 KKK41650.1 - 0.0008 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fer4_8 PF13183.6 KKK41650.1 - 0.0014 19.0 24.4 0.3 11.5 2.0 4.7 5 0 0 5 5 4 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK41650.1 - 0.0015 19.4 23.3 0.72 10.8 1.4 5.0 5 0 0 5 5 4 2 4Fe-4S double cluster binding domain Pyr_redox_3 PF13738.6 KKK41650.1 - 0.0017 17.6 0.9 0.012 14.9 0.4 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK41650.1 - 0.0019 17.0 1.9 0.009 14.8 2.1 1.9 1 1 1 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KKK41650.1 - 0.0046 16.2 0.9 0.011 15.0 0.7 1.6 1 1 1 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KKK41650.1 - 0.0055 16.0 0.9 0.015 14.6 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KKK41650.1 - 0.018 14.4 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DAO PF01266.24 KKK41650.1 - 0.085 12.4 4.1 0.15 11.6 3.5 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fer4_17 PF13534.6 KKK41650.1 - 0.35 11.5 29.9 0.2 12.2 2.2 4.8 4 1 2 6 6 6 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK41650.1 - 5.4 7.8 21.5 1.4 9.7 0.7 4.3 4 0 0 4 4 3 0 4Fe-4S single cluster domain Peptidase_M13_N PF05649.13 KKK41651.1 - 2e-84 284.5 3.8 2e-84 284.5 3.8 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 KKK41651.1 - 8e-63 211.7 0.4 1.4e-62 211.0 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M13 TraI_2B PF18340.1 KKK41651.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain PI3K_1B_p101 PF10486.9 KKK41651.1 - 0.21 9.3 2.2 0.61 7.8 0.8 1.9 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CxxCxxCC PF03692.15 KKK41652.1 - 7.3e-11 42.6 2.1 1.3e-10 41.8 2.1 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Type_ISP_C PF18135.1 KKK41653.1 - 1.5e-47 162.3 4.3 1.9e-46 158.7 4.3 2.2 1 1 0 1 1 1 1 Type ISP C-terminal specificity domain Eco57I PF07669.11 KKK41653.1 - 0.00034 21.1 1.1 0.0022 18.5 0.2 2.9 2 1 0 2 2 2 1 Eco57I restriction-modification methylase AMP-binding PF00501.28 KKK41655.1 - 4.8e-06 25.4 0.0 5.1e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme SRP19 PF01922.17 KKK41656.1 - 1.9e-20 73.6 0.2 2.3e-20 73.3 0.2 1.1 1 0 0 1 1 1 1 SRP19 protein HypA PF01155.19 KKK41657.1 - 2.5e-28 98.3 0.3 2.8e-28 98.2 0.3 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA tRNA-synt_1f PF01921.18 KKK41657.1 - 0.038 12.9 0.1 0.038 12.9 0.1 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) Zn_Tnp_IS1595 PF12760.7 KKK41657.1 - 0.046 13.7 0.8 0.15 12.1 0.7 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-DNL PF05180.12 KKK41657.1 - 0.093 12.7 1.1 0.19 11.7 1.1 1.6 1 0 0 1 1 1 0 DNL zinc finger RNA_POL_M_15KD PF02150.16 KKK41657.1 - 0.097 12.6 1.2 0.69 9.8 1.2 2.0 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit Ribosomal_S8e PF01201.22 KKK41658.1 - 8.1e-28 97.3 2.4 9.3e-28 97.1 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SGL PF08450.12 KKK41659.1 - 5e-11 42.6 0.0 5.5e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Proteasome PF00227.26 KKK41660.1 - 1.5e-39 135.5 0.2 1.7e-39 135.3 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Prok-JAB PF14464.6 KKK41661.1 - 4.7e-05 23.2 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 KKK41661.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3778 PF12620.8 KKK41661.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) DEAD PF00270.29 KKK41664.1 - 3e-51 173.7 0.1 1.2e-49 168.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK41664.1 - 9.7e-32 109.6 4.0 5.9e-29 100.7 0.3 3.4 4 0 0 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.15 KKK41664.1 - 5e-10 39.6 0.2 1.7e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KKK41664.1 - 0.00048 19.5 0.1 0.00091 18.6 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KKK41664.1 - 0.005 16.8 0.1 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain Lipase_GDSL_3 PF14606.6 KKK41664.1 - 0.0085 16.2 0.2 0.084 13.0 0.1 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF3800 PF12686.7 KKK41665.1 - 0.025 15.2 10.7 40 4.9 1.2 5.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3800) 5-FTHF_cyc-lig PF01812.20 KKK41665.1 - 0.44 10.4 3.4 1.2 9.0 0.8 2.7 2 1 1 3 3 3 0 5-formyltetrahydrofolate cyclo-ligase family N6_Mtase PF02384.16 KKK41666.1 - 3.1e-12 46.4 1.4 6.6e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 N-6 DNA Methylase Methyltransf_31 PF13847.6 KKK41666.1 - 0.039 13.8 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 KKK41666.1 - 0.052 13.2 0.0 3 7.5 0.0 2.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 PLDc_2 PF13091.6 KKK41667.1 - 0.0089 15.9 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 PLD-like domain LolA PF03548.15 KKK41667.1 - 0.047 13.4 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA CHAT PF12770.7 KKK41668.1 - 0.015 14.7 0.0 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 CHAT domain Actin PF00022.19 KKK41669.1 - 1.2e-49 169.1 0.0 2.2e-48 164.9 0.0 2.0 1 1 0 1 1 1 1 Actin MGDG_synth PF06925.11 KKK41669.1 - 0.099 12.8 0.4 0.099 12.8 0.4 1.7 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase MreB_Mbl PF06723.13 KKK41669.1 - 0.13 11.1 0.1 1.6 7.5 0.1 2.4 1 1 0 1 1 1 0 MreB/Mbl protein PBC PF03792.13 KKK41670.1 - 0.00059 19.7 0.8 0.0019 18.0 0.5 2.0 1 1 1 2 2 2 1 PBC domain MbeD_MobD PF04899.12 KKK41670.1 - 0.028 14.5 0.3 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 MbeD/MobD like ACT PF01842.25 KKK41671.1 - 2e-05 24.3 0.0 4.5e-05 23.1 0.0 1.7 1 1 1 2 2 2 1 ACT domain ACT_4 PF13291.6 KKK41671.1 - 0.055 14.1 0.0 0.12 13.0 0.0 1.7 1 1 0 1 1 1 0 ACT domain CoA_binding_2 PF13380.6 KKK41677.1 - 6.9e-23 81.3 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK41677.1 - 2.9e-08 34.3 0.4 1.2e-07 32.3 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 KKK41677.1 - 0.015 15.1 0.1 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain DHO_dh PF01180.21 KKK41677.1 - 0.023 13.9 0.4 0.028 13.7 0.4 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Tox-PL-2 PF15643.6 KKK41678.1 - 0.047 13.8 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 Papain fold toxin 2 FAD_binding_4 PF01565.23 KKK41679.1 - 1.7e-20 73.2 0.0 2.4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain CCG PF02754.16 KKK41680.1 - 3.6e-23 81.6 11.2 2.7e-11 43.5 1.9 4.4 3 1 0 3 3 3 2 Cysteine-rich domain Fer4_17 PF13534.6 KKK41680.1 - 2.3e-05 24.8 9.2 0.00022 21.7 0.1 3.4 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK41680.1 - 3.8e-05 24.1 1.7 3.8e-05 24.1 1.7 3.6 3 2 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41680.1 - 0.0061 16.6 11.0 0.0069 16.5 0.5 3.6 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41680.1 - 0.036 14.2 0.3 0.036 14.2 0.3 3.6 4 0 0 4 4 4 0 4Fe-4S dicluster domain TaqI_C PF12950.7 KKK41680.1 - 0.051 13.7 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Fer4_7 PF12838.7 KKK41680.1 - 0.081 13.5 0.4 0.081 13.5 0.4 3.6 4 0 0 4 4 4 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41680.1 - 2.4 8.3 15.2 1.6 8.9 2.8 3.7 4 0 0 4 4 4 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41680.1 - 3.9 7.4 15.0 6.5 6.7 1.0 3.7 3 0 0 3 3 3 0 4Fe-4S binding domain Peptidase_C13 PF01650.18 KKK41681.1 - 2.1e-11 43.9 1.3 4.4e-11 42.8 1.3 1.4 1 1 0 1 1 1 1 Peptidase C13 family Big_5 PF13205.6 KKK41682.1 - 0.02 15.6 2.1 0.03 15.0 2.1 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain Myb_DNA-bind_4 PF13837.6 KKK41683.1 - 0.11 12.8 10.6 0.49 10.8 0.7 4.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Latarcin PF10279.9 KKK41683.1 - 0.63 10.5 13.7 1.6 9.2 2.5 5.8 2 2 0 2 2 2 0 Latarcin precursor Helicase_C PF00271.31 KKK41684.1 - 1e-22 80.6 5.3 2.6e-22 79.3 0.7 3.3 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK41684.1 - 1.1e-21 77.6 0.0 1.1e-21 77.6 0.0 3.4 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK41684.1 - 1.5e-20 73.7 0.3 2.9e-19 69.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KKK41684.1 - 0.0084 15.6 0.0 0.037 13.5 0.0 2.1 1 1 0 1 1 1 1 PhoH-like protein SNF2_N PF00176.23 KKK41684.1 - 0.021 13.5 0.3 0.045 12.5 0.0 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_19 PF13245.6 KKK41684.1 - 0.027 14.8 0.0 0.092 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Wbp11 PF09429.10 KKK41684.1 - 0.12 12.8 4.9 1.1 9.7 0.5 2.9 2 0 0 2 2 2 0 WW domain binding protein 11 Lactamase_B PF00753.27 KKK41685.1 - 2.4e-19 70.1 0.0 3.9e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK41685.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Metallophos PF00149.28 KKK41685.1 - 0.01 16.4 0.1 0.049 14.1 0.1 2.0 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Rep_fac_C PF08542.11 KKK41685.1 - 0.07 13.5 0.0 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF892 PF05974.12 KKK41685.1 - 0.2 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Abhydrolase_1 PF00561.20 KKK41686.1 - 6.3e-21 75.2 0.0 2.5e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK41686.1 - 3e-11 44.3 0.0 4.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK41686.1 - 5.8e-11 42.1 0.0 6.9e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK41686.1 - 2.3e-05 23.3 0.0 0.0069 15.1 0.0 2.1 2 0 0 2 2 2 2 Ndr family DUF3106 PF11304.8 KKK41686.1 - 0.0055 17.1 3.1 0.013 15.9 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) COX4 PF02936.14 KKK41686.1 - 0.04 13.9 3.2 0.14 12.2 3.2 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase subunit IV NST1 PF13945.6 KKK41686.1 - 0.07 13.2 2.3 0.12 12.5 2.3 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Abhydrolase_5 PF12695.7 KKK41686.1 - 0.098 12.4 0.0 4.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ribosomal_S21 PF01165.20 KKK41686.1 - 1.1 9.0 6.2 3.2 7.5 6.2 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 adh_short_C2 PF13561.6 KKK41687.1 - 2.2e-53 181.2 0.0 2.7e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK41687.1 - 2.3e-46 157.7 0.0 3.1e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK41687.1 - 1.9e-18 67.0 0.0 2.8e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK41687.1 - 0.029 13.8 0.0 0.073 12.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.16 KKK41687.1 - 0.044 13.4 0.1 0.092 12.4 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Tex_YqgF PF16921.5 KKK41687.1 - 0.059 13.8 0.2 0.19 12.2 0.2 1.8 2 0 0 2 2 2 0 Tex protein YqgF-like domain CBFD_NFYB_HMF PF00808.23 KKK41688.1 - 5.3e-08 33.0 0.0 6.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK41688.1 - 4.9e-05 23.7 0.0 5.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KKK41688.1 - 0.00046 20.5 0.0 0.00047 20.5 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KKK41688.1 - 0.0021 18.1 0.0 0.0025 17.9 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 KKK41688.1 - 0.0066 16.6 0.4 0.0093 16.1 0.4 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 KKK41688.1 - 0.013 15.6 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DZR PF12773.7 KKK41689.1 - 0.0062 16.5 1.3 0.0076 16.3 1.3 1.1 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_4 PF13717.6 KKK41689.1 - 0.011 15.6 0.7 1.6 8.7 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-CRD PF17979.1 KKK41689.1 - 0.014 15.5 0.4 0.016 15.3 0.4 1.1 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions zf-HC5HC2H PF13771.6 KKK41689.1 - 0.021 15.0 0.2 0.024 14.9 0.2 1.1 1 0 0 1 1 1 0 PHD-like zinc-binding domain Herpes_glycoH_C PF17488.2 KKK41689.1 - 0.057 13.2 0.2 0.057 13.2 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain zf-ribbon_3 PF13248.6 KKK41689.1 - 0.1 12.0 0.3 0.1 12.0 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 KKK41689.1 - 0.18 11.6 4.7 1.3 8.7 0.5 2.2 1 1 1 2 2 2 0 Ribosomal protein S27 zf-BED PF02892.15 KKK41689.1 - 0.23 11.5 6.4 1 9.5 0.7 2.1 1 1 1 2 2 2 0 BED zinc finger LRR_8 PF13855.6 KKK41692.1 - 2e-08 33.8 14.8 3.6e-08 33.1 1.8 4.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 KKK41692.1 - 0.00013 22.3 7.1 0.00013 22.3 7.1 4.7 3 2 2 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK41692.1 - 0.041 14.4 7.9 6.9 7.6 0.7 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Fe-ADH PF00465.19 KKK41700.1 - 1e-05 24.6 0.2 1e-05 24.6 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase NMT1_2 PF13379.6 KKK41702.1 - 3.4e-17 63.0 0.0 5.2e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 KKK41702.1 - 4e-08 33.5 0.0 7.9e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like DUF3834 PF12916.7 KKK41702.1 - 0.01 15.1 0.4 0.16 11.2 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3834) Mgr1 PF08602.10 KKK41703.1 - 0.021 13.7 1.9 0.024 13.5 1.9 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4364 PF14277.6 KKK41703.1 - 0.022 14.5 5.6 0.028 14.1 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) ERF PF04404.12 KKK41705.1 - 0.018 14.9 2.2 0.043 13.7 2.2 1.6 1 0 0 1 1 1 0 ERF superfamily Peptidase_M29 PF02073.15 KKK41706.1 - 1.3e-14 53.8 0.0 1.4e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) Thiolase_C PF02803.18 KKK41709.1 - 4.1e-41 139.5 0.2 1.5e-40 137.6 0.1 2.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 KKK41709.1 - 1.1e-31 110.2 0.8 2.6e-30 105.6 0.2 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain Dodecin PF07311.12 KKK41710.1 - 2.8e-14 53.1 0.4 3.2e-14 52.9 0.4 1.1 1 0 0 1 1 1 1 Dodecin DUF4954 PF16314.5 KKK41710.1 - 0.063 11.4 0.5 0.066 11.3 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Clathrin_H_link PF13838.6 KKK41710.1 - 0.17 11.8 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Clathrin-H-link TPR_1 PF00515.28 KKK41712.1 - 7.7e-26 88.8 13.0 9e-11 41.1 2.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK41712.1 - 6e-22 75.9 7.5 2.3e-08 33.5 0.8 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK41712.1 - 1e-20 72.1 11.9 5.4e-09 35.6 0.8 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKK41712.1 - 4e-18 65.7 0.0 2.2e-07 31.3 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK41712.1 - 2.4e-17 62.3 9.8 2.8e-05 23.7 0.0 4.2 2 1 2 4 4 4 3 TPR repeat TPR_12 PF13424.6 KKK41712.1 - 3.5e-13 49.6 0.3 2.4e-09 37.3 0.4 2.9 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK41712.1 - 4e-13 49.1 0.6 0.0061 17.1 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK41712.1 - 5.5e-13 48.0 0.3 0.00058 19.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK41712.1 - 3.2e-12 46.9 0.0 4.1e-06 27.3 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KKK41712.1 - 1.7e-11 43.7 5.7 0.0011 19.2 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK41712.1 - 8.3e-11 41.8 0.0 0.45 11.5 0.0 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KKK41712.1 - 9.9e-08 31.9 3.8 0.026 14.6 0.2 4.4 2 1 2 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KKK41712.1 - 1.8e-06 27.7 0.6 0.18 11.7 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KKK41712.1 - 1.8e-06 28.0 0.0 0.013 15.6 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK41712.1 - 1.9e-05 24.8 3.6 0.015 15.5 0.9 2.9 1 1 3 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 EST1_DNA_bind PF10373.9 KKK41712.1 - 3.7e-05 23.4 0.7 0.0001 21.9 0.1 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain TPR_18 PF13512.6 KKK41712.1 - 0.00021 21.5 1.4 0.00086 19.4 0.4 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat YfiO PF13525.6 KKK41712.1 - 0.0012 18.7 1.0 0.0019 17.9 1.0 1.6 1 1 0 1 1 1 1 Outer membrane lipoprotein NARP1 PF12569.8 KKK41712.1 - 0.0049 15.8 1.1 0.018 14.0 0.3 2.0 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 Sel1 PF08238.12 KKK41712.1 - 0.0081 16.8 2.4 1.5 9.6 0.1 2.9 2 1 0 2 2 2 1 Sel1 repeat MIT PF04212.18 KKK41712.1 - 0.032 14.3 7.6 2.8 8.1 0.1 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 KKK41712.1 - 0.055 12.8 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 MalT-like TPR region SHNi-TPR PF10516.9 KKK41712.1 - 0.063 12.7 0.9 6.4 6.3 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR DUF627 PF04781.12 KKK41712.1 - 0.13 12.3 0.7 12 6.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF627) dUTPase PF00692.19 KKK41713.1 - 3.6e-24 84.9 0.0 5.3e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 dUTPase Glu-tRNAGln PF02686.15 KKK41716.1 - 2.8e-19 69.2 0.2 4.8e-19 68.4 0.0 1.4 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit RecG_N PF17190.4 KKK41716.1 - 0.0073 17.0 0.2 0.011 16.4 0.1 1.4 1 1 0 1 1 1 1 RecG N-terminal helical domain Med15_fungi PF05397.12 KKK41716.1 - 0.044 14.1 0.0 0.094 13.0 0.0 1.6 1 1 0 1 1 1 0 Mediator complex subunit 15 zf-TFIIB PF13453.6 KKK41717.1 - 0.049 13.0 0.1 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF2600 PF10776.9 KKK41720.1 - 0.0015 17.5 1.0 0.0022 16.9 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2600) Glyco_tran_WbsX PF14307.6 KKK41720.1 - 0.023 14.2 3.5 0.023 14.1 1.6 1.8 1 1 0 2 2 2 0 Glycosyltransferase WbsX EF-hand_7 PF13499.6 KKK41720.1 - 0.09 13.2 0.9 0.96 9.9 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain pair DUF2080 PF09853.9 KKK41720.1 - 0.21 11.4 0.8 1.1 9.1 0.2 2.5 3 0 0 3 3 3 0 Putative transposon-encoded protein (DUF2080) Glu-tRNAGln PF02686.15 KKK41721.1 - 8.3e-20 70.8 0.1 1.5e-19 70.1 0.0 1.4 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit RecG_N PF17190.4 KKK41721.1 - 0.016 15.9 0.1 0.025 15.3 0.1 1.4 1 0 0 1 1 1 0 RecG N-terminal helical domain Med15_fungi PF05397.12 KKK41721.1 - 0.049 13.9 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 PriA_C PF18074.1 KKK41721.1 - 0.11 13.3 0.0 0.13 13.1 0.0 1.2 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain zf-TFIIB PF13453.6 KKK41722.1 - 0.071 12.5 0.1 0.7 9.3 0.0 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger Ferritin PF00210.24 KKK41722.1 - 0.074 13.0 0.0 0.095 12.6 0.0 1.1 1 0 0 1 1 1 0 Ferritin-like domain Cnn_1N PF07989.11 KKK41723.1 - 1.6 8.9 8.7 0.77 10.0 2.9 3.2 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 AAA_28 PF13521.6 KKK41725.1 - 0.002 18.4 0.2 0.002 18.4 0.2 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK41725.1 - 0.0095 16.5 0.4 0.0095 16.5 0.4 1.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK41725.1 - 0.02 15.3 0.2 0.021 15.3 0.2 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK41725.1 - 0.042 13.9 0.3 0.043 13.8 0.3 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KKK41725.1 - 0.042 14.2 0.2 0.043 14.1 0.2 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK41725.1 - 0.049 14.0 0.1 0.049 14.0 0.1 1.0 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KKK41725.1 - 0.059 13.3 0.1 0.059 13.3 0.1 1.0 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KKK41725.1 - 0.078 13.5 0.7 0.078 13.5 0.7 1.0 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KKK41725.1 - 0.092 11.9 0.1 0.092 11.9 0.1 1.0 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 KKK41725.1 - 0.16 11.6 0.1 0.16 11.6 0.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 KKK41725.1 - 0.21 10.7 0.4 0.21 10.7 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 KKK41726.1 - 3.8e-07 30.0 0.0 8.7e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK41726.1 - 1.4e-06 28.3 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NifU PF01106.17 KKK41733.1 - 8.7e-27 93.1 0.3 9.5e-27 92.9 0.3 1.0 1 0 0 1 1 1 1 NifU-like domain FeS_assembly_P PF01883.19 KKK41733.1 - 0.0069 16.5 0.0 0.0087 16.2 0.0 1.1 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein HydF_tetramer PF18133.1 KKK41733.1 - 0.034 13.9 0.0 0.036 13.8 0.0 1.1 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain CdiA_C PF18451.1 KKK41733.1 - 0.18 12.0 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain DUF2207 PF09972.9 KKK41734.1 - 0.04 12.7 3.5 0.061 12.1 3.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Succ_CoA_lig PF13607.6 KKK41735.1 - 7.7e-17 61.4 0.1 2e-15 56.8 0.0 2.9 3 1 1 4 4 4 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK41735.1 - 1.6e-14 54.4 0.0 6.3e-12 46.0 0.0 3.1 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 KKK41735.1 - 0.023 15.3 0.0 0.069 13.8 0.0 1.9 1 0 0 1 1 1 0 CoA binding domain Ribosomal_L16 PF00252.18 KKK41736.1 - 5.8e-24 84.6 0.4 8e-24 84.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e YvrJ PF12841.7 KKK41737.1 - 0.03 13.8 0.9 0.037 13.6 0.9 1.2 1 0 0 1 1 1 0 YvrJ protein family MerR-DNA-bind PF09278.11 KKK41737.1 - 0.071 13.6 0.0 0.073 13.6 0.0 1.0 1 0 0 1 1 1 0 MerR, DNA binding Osmo_CC PF08946.10 KKK41737.1 - 0.076 13.3 1.6 0.1 12.8 1.6 1.2 1 0 0 1 1 1 0 Osmosensory transporter coiled coil LRR_4 PF12799.7 KKK41738.1 - 1.2e-12 47.8 10.5 1.9e-07 31.3 1.4 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK41738.1 - 6.7e-11 41.8 7.7 8e-10 38.3 1.8 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KKK41738.1 - 0.008 16.6 2.6 3.1 8.7 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich Repeat Thioredoxin PF00085.20 KKK41741.1 - 6.4e-22 77.5 0.0 8.9e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK41741.1 - 3.2e-09 37.0 1.4 9.8e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KKK41741.1 - 1.9e-06 28.2 0.0 5.1e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KKK41741.1 - 3.3e-06 27.2 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 KKK41741.1 - 6.9e-05 22.8 0.1 0.00015 21.7 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK41741.1 - 0.00021 21.1 0.1 0.0018 18.0 0.0 1.9 1 1 1 2 2 2 1 Redoxin DUF953 PF06110.11 KKK41741.1 - 0.0011 18.6 0.0 0.003 17.2 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) HyaE PF07449.11 KKK41741.1 - 0.0042 17.0 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 KKK41741.1 - 0.0073 15.7 0.0 0.008 15.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 KKK41741.1 - 0.0098 15.8 0.1 0.012 15.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 KKK41741.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 KKK41741.1 - 0.059 13.1 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Radical_SAM PF04055.21 KKK41742.1 - 3.5e-11 43.8 0.2 1e-10 42.3 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Glyco_hydro_38N PF01074.22 KKK41742.1 - 0.00012 21.6 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain DeoC PF01791.9 KKK41742.1 - 0.012 15.2 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 DeoC/LacD family aldolase Fer4_14 PF13394.6 KKK41742.1 - 0.013 15.7 0.9 0.031 14.4 0.9 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain Na_Ca_ex_C PF16494.5 KKK41742.1 - 0.042 14.3 0.5 0.067 13.7 0.5 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Ribul_P_3_epim PF00834.19 KKK41742.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family adh_short PF00106.25 KKK41743.1 - 8.2e-44 149.4 0.1 1e-43 149.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK41743.1 - 8.5e-35 120.4 0.0 1.7e-34 119.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK41743.1 - 4.6e-13 49.5 0.0 6.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KKK41743.1 - 0.0041 17.4 0.1 0.0085 16.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KKK41743.1 - 0.0086 15.2 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Alba PF01918.21 KKK41743.1 - 0.025 14.4 2.2 0.026 14.3 0.7 1.9 2 1 0 2 2 2 0 Alba Epimerase PF01370.21 KKK41743.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KKK41743.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LUD_dom PF02589.15 KKK41744.1 - 3.6e-30 105.1 5.4 1.4e-29 103.2 5.4 1.8 1 1 0 1 1 1 1 LUD domain Fer4_8 PF13183.6 KKK41744.1 - 1.3e-08 35.2 2.2 2.1e-08 34.5 1.4 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41744.1 - 4.2e-05 23.6 4.4 0.00016 21.8 4.4 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK41744.1 - 0.00022 21.1 9.3 0.086 13.0 1.2 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK41744.1 - 0.00042 20.9 7.2 0.0016 19.0 7.2 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41744.1 - 0.0022 18.1 12.1 0.026 14.6 2.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41744.1 - 0.0043 17.6 10.2 0.037 14.6 9.3 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK41744.1 - 0.0098 16.8 6.8 0.88 10.5 1.3 2.8 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain RNA_helicase PF00910.22 KKK41744.1 - 0.011 16.1 1.0 2.3 8.7 0.8 2.3 2 0 0 2 2 2 0 RNA helicase Fer4_22 PF17179.4 KKK41744.1 - 0.016 16.0 8.1 0.37 11.7 0.5 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41744.1 - 0.04 14.1 13.3 1.2 9.3 13.3 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 KKK41744.1 - 0.11 12.3 4.1 1 9.2 0.7 2.5 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_18 PF13746.6 KKK41744.1 - 0.22 11.7 5.4 0.48 10.6 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK41744.1 - 1.5 9.5 11.0 3.1 8.5 3.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK41744.1 - 1.6 9.9 14.9 0.65 11.1 4.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 KKK41744.1 - 6.8 6.7 15.1 0.65 9.9 1.8 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain CCG PF02754.16 KKK41745.1 - 1.2e-20 73.5 1.6 9.6e-12 45.0 0.1 2.2 2 0 0 2 2 2 2 Cysteine-rich domain Fer4 PF00037.27 KKK41746.1 - 3.4e-09 36.1 22.0 2.9e-07 30.0 4.0 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK41746.1 - 5.4e-09 36.5 21.5 2.2e-08 34.6 10.3 3.1 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41746.1 - 5.1e-08 32.9 8.9 5.1e-08 32.9 8.9 2.7 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41746.1 - 1.9e-07 31.1 12.7 1.9e-07 31.1 12.7 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41746.1 - 8.9e-07 29.0 11.9 8.9e-07 29.0 11.9 2.6 1 1 2 3 3 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41746.1 - 2.6e-05 24.1 18.3 0.00032 20.6 3.5 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK41746.1 - 6.1e-05 22.9 11.4 0.002 18.1 2.8 3.4 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KKK41746.1 - 0.00052 20.3 15.3 0.0013 19.1 3.8 3.6 5 0 0 5 5 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK41746.1 - 0.001 20.0 0.9 0.001 20.0 0.9 3.6 2 1 1 3 3 3 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK41746.1 - 0.0063 16.9 0.5 0.0063 16.9 0.5 3.3 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK41746.1 - 0.0086 16.3 8.1 0.0086 16.3 8.1 2.1 1 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41746.1 - 0.019 15.5 1.5 0.019 15.5 1.5 3.6 1 1 5 6 6 5 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK41746.1 - 0.054 14.3 1.0 0.054 14.3 1.0 3.4 3 1 0 3 3 2 0 4Fe-4S dicluster domain PRO8NT PF08082.11 KKK41746.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Fer4_3 PF12798.7 KKK41746.1 - 0.078 14.0 6.4 0.078 14.0 6.4 3.8 5 0 0 5 5 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK41746.1 - 0.098 13.2 11.4 0.21 12.2 2.3 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I MM_CoA_mutase PF01642.22 KKK41747.1 - 4.1e-222 738.3 0.2 4.7e-222 738.1 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 KKK41748.1 - 6.2e-21 74.7 0.1 7.1e-21 74.5 0.1 1.0 1 0 0 1 1 1 1 B12 binding domain Peripla_BP_6 PF13458.6 KKK41748.1 - 0.0039 16.9 0.0 0.0043 16.8 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein GATase1_like PF07090.11 KKK41748.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative glutamine amidotransferase MoCF_biosynth PF00994.24 KKK41748.1 - 0.11 12.1 0.2 0.68 9.6 0.0 1.9 1 1 0 2 2 2 0 Probable molybdopterin binding domain MeaB PF03308.16 KKK41749.1 - 3e-87 292.0 0.7 3.6e-87 291.7 0.7 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 KKK41749.1 - 1.1e-06 28.6 2.5 0.018 14.8 0.1 2.5 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein cobW PF02492.19 KKK41749.1 - 7.5e-05 22.4 5.3 0.00032 20.3 4.1 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 KKK41749.1 - 0.00019 20.8 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 KAP family P-loop domain SRP54 PF00448.22 KKK41749.1 - 0.00031 20.4 1.1 0.0032 17.1 1.1 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.23 KKK41749.1 - 0.0013 18.8 0.0 0.0053 16.8 0.0 2.1 2 1 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 KKK41749.1 - 0.0024 17.7 0.9 0.0045 16.8 0.2 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 KKK41749.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 KKK41749.1 - 0.023 13.8 0.3 0.023 13.8 0.3 2.1 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) AAA_19 PF13245.6 KKK41749.1 - 0.023 15.0 2.1 0.067 13.5 2.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK41749.1 - 0.025 14.3 0.5 0.073 12.8 0.5 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK41749.1 - 0.028 14.7 0.0 0.079 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KKK41749.1 - 0.046 13.6 2.2 0.15 12.0 0.2 2.6 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 KKK41749.1 - 0.074 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KKK41749.1 - 0.087 12.9 5.7 0.15 12.1 2.9 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KKK41749.1 - 0.095 13.3 0.9 0.31 11.6 0.9 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK41749.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 KKK41749.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KKK41749.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.2 2 1 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 KKK41749.1 - 0.14 12.0 1.7 6.3 6.7 0.0 2.7 2 1 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 KKK41749.1 - 0.2 11.9 0.5 0.4 10.9 0.5 1.5 1 0 0 1 1 1 0 AAA domain PriX PF18689.1 KKK41749.1 - 0.3 11.4 3.9 0.22 11.9 1.1 2.1 1 1 1 2 2 2 0 Primase X DUF87 PF01935.17 KKK41749.1 - 0.6 10.2 9.4 1.8 8.6 0.6 2.9 2 2 0 2 2 2 0 Helicase HerA, central domain MCM_OB PF17207.3 KKK41750.1 - 0.048 13.5 0.2 0.054 13.4 0.2 1.0 1 0 0 1 1 1 0 MCM OB domain Elf1 PF05129.13 KKK41750.1 - 0.18 11.9 7.9 1.3 9.1 0.4 2.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like LRR_8 PF13855.6 KKK41751.1 - 2e-43 146.0 64.2 1.1e-14 53.9 9.2 7.9 4 2 4 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 KKK41751.1 - 2.7e-23 81.6 95.0 5.9e-06 26.5 5.6 9.4 4 2 8 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK41751.1 - 4.5e-10 38.6 54.4 0.044 14.3 1.0 12.3 11 1 1 12 12 12 5 Leucine Rich Repeat HEAT_2 PF13646.6 KKK41751.1 - 2.3e-06 27.9 0.0 4.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 HEAT repeats LRR_6 PF13516.6 KKK41751.1 - 8.8e-06 25.4 66.4 0.049 13.7 0.5 12.6 14 0 0 14 14 14 5 Leucine Rich repeat LRR_9 PF14580.6 KKK41751.1 - 9.3e-05 22.0 23.1 0.0028 17.2 4.2 4.1 2 2 2 5 5 5 3 Leucine-rich repeat RsmF_methylt_CI PF17126.5 KKK41751.1 - 0.0035 17.3 0.6 21 5.2 0.0 4.7 3 1 2 5 5 5 1 RsmF rRNA methyltransferase first C-terminal domain PAS_9 PF13426.7 KKK41755.1 - 1.9e-70 233.7 32.4 7e-12 45.5 0.1 10.3 10 0 0 10 10 10 10 PAS domain PAS_3 PF08447.12 KKK41755.1 - 9.6e-68 224.5 5.1 2.7e-13 50.0 0.0 9.3 9 0 0 9 9 9 7 PAS fold PAS PF00989.25 KKK41755.1 - 5e-63 210.1 5.4 3e-07 30.4 0.0 10.3 10 0 0 10 10 10 10 PAS fold PAS_4 PF08448.10 KKK41755.1 - 5.8e-54 181.0 0.0 2.6e-07 30.8 0.0 10.7 10 1 0 10 10 10 7 PAS fold PAS_8 PF13188.7 KKK41755.1 - 4.5e-46 154.2 0.2 5.1e-08 32.8 0.0 9.6 9 0 0 9 9 9 7 PAS domain PAS_7 PF12860.7 KKK41755.1 - 6.1e-09 36.1 18.2 6e-05 23.2 0.0 9.3 12 1 0 12 12 12 1 PAS fold PAS_11 PF14598.6 KKK41755.1 - 1.7e-07 31.3 2.3 0.00069 19.7 0.0 5.2 7 0 0 7 7 7 1 PAS domain PAS_12 PF18095.1 KKK41755.1 - 0.0041 16.8 9.9 1.2 8.8 0.1 4.8 4 0 0 4 4 4 2 UPF0242 C-terminal PAS-like domain HisKA PF00512.25 KKK41755.1 - 0.035 14.1 0.7 0.15 12.2 0.0 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain ATP-synt_F PF01990.17 KKK41755.1 - 0.18 12.1 8.1 7.4 7.0 0.3 4.5 4 0 0 4 4 4 0 ATP synthase (F/14-kDa) subunit CdiA_C PF18451.1 KKK41755.1 - 0.46 10.7 12.2 0.1 12.9 1.2 5.6 5 0 0 5 5 5 0 Contact-dependent growth inhibition CdiA C-terminal domain DUF87 PF01935.17 KKK41759.1 - 6.5e-16 59.1 6.5 1.1e-13 51.8 0.1 3.4 2 1 1 3 3 3 1 Helicase HerA, central domain AAA_10 PF12846.7 KKK41759.1 - 8.2e-08 31.6 0.8 0.0004 19.4 0.0 3.1 2 1 1 3 3 3 2 AAA-like domain DUF853 PF05872.12 KKK41759.1 - 1e-07 31.0 0.0 0.0099 14.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) TrwB_AAD_bind PF10412.9 KKK41759.1 - 1e-05 24.6 0.0 0.05 12.5 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.12 KKK41759.1 - 0.0005 19.8 0.8 0.0088 15.7 0.0 2.7 3 1 0 3 3 3 1 Zonular occludens toxin (Zot) ZapB PF06005.12 KKK41759.1 - 0.0051 17.2 0.6 0.0051 17.2 0.6 2.5 3 1 0 3 3 2 1 Cell division protein ZapB TMF_TATA_bd PF12325.8 KKK41759.1 - 0.011 16.0 8.9 0.025 14.8 1.5 2.9 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.11 KKK41759.1 - 0.014 15.4 1.8 0.054 13.5 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) AAA_22 PF13401.6 KKK41759.1 - 0.017 15.4 0.5 0.3 11.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK41759.1 - 0.018 15.6 0.4 0.14 12.7 0.0 2.6 3 0 0 3 3 2 0 ABC transporter WD40_alt PF14077.6 KKK41759.1 - 0.027 14.3 0.3 0.12 12.2 0.3 2.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif AAA_16 PF13191.6 KKK41759.1 - 0.034 14.5 0.1 0.29 11.5 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 KKK41759.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Microtubule binding ResIII PF04851.15 KKK41759.1 - 0.05 13.6 0.0 0.31 11.0 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Vps51 PF08700.11 KKK41759.1 - 0.063 13.4 1.6 5.2 7.2 0.0 3.3 4 0 0 4 4 4 0 Vps51/Vps67 AAA_24 PF13479.6 KKK41759.1 - 0.09 12.5 0.7 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKK41759.1 - 0.093 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KKK41759.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Lzipper-MIP1 PF14389.6 KKK41759.1 - 0.13 12.6 0.9 0.36 11.1 0.9 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.15 KKK41759.1 - 0.21 11.4 5.3 1.5 8.7 0.1 3.1 3 0 0 3 3 3 0 Septum formation initiator MetOD2 PF18548.1 KKK41759.1 - 0.4 10.8 3.0 8.1 6.6 0.2 2.6 2 0 0 2 2 2 0 Metanogen output domain 2 BLOC1_2 PF10046.9 KKK41759.1 - 0.52 10.6 5.0 3.2 8.1 0.3 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MPS2 PF17060.5 KKK41759.1 - 0.7 9.1 6.6 1.5 8.0 6.6 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 Med9 PF07544.13 KKK41759.1 - 0.89 9.7 3.6 25 5.0 0.5 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Cnn_1N PF07989.11 KKK41759.1 - 1.3 9.2 6.8 0.67 10.2 0.5 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF5603 PF18231.1 KKK41759.1 - 2.5 8.5 7.9 15 6.0 0.0 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF5603) bZIP_2 PF07716.15 KKK41759.1 - 4.7 7.4 9.2 0.53 10.4 0.1 3.3 4 0 0 4 4 3 0 Basic region leucine zipper DUF3496 PF12001.8 KKK41759.1 - 5.3 7.5 9.2 7 7.1 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3496) Tropomyosin_1 PF12718.7 KKK41759.1 - 6.9 6.8 13.8 0.35 11.0 1.4 2.5 2 1 0 2 2 2 0 Tropomyosin like DUF2156 PF09924.9 KKK41760.1 - 1.1e-19 70.6 0.0 1.2e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Peptidase_M20 PF01546.28 KKK41765.1 - 0.00012 21.8 0.1 0.00024 20.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK41765.1 - 0.00029 20.7 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ECH_1 PF00378.20 KKK41766.1 - 9.4e-45 152.9 0.0 1e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK41766.1 - 9.7e-21 74.6 0.0 8.6e-20 71.5 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECF_trnsprt PF12822.7 KKK41767.1 - 2.5e-07 31.0 29.9 3.5e-07 30.5 29.9 1.2 1 0 0 1 1 1 1 ECF transporter, substrate-specific component MASE5 PF17178.4 KKK41767.1 - 0.017 14.9 2.9 0.017 14.9 2.9 1.9 2 0 0 2 2 2 0 Membrane-associated sensor RFC1 PF08519.12 KKK41768.1 - 0.028 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain DUF768 PF05589.11 KKK41768.1 - 0.073 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Ferrochelatase PF00762.19 KKK41768.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ferrochelatase Alkyl_sulf_dimr PF14863.6 KKK41776.1 - 8.5e-31 107.3 0.0 1.4e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KKK41776.1 - 4.4e-12 46.4 0.0 1.2e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK41776.1 - 0.00047 19.7 0.0 0.00097 18.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3477 PF11963.8 KKK41776.1 - 0.088 12.0 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) Methyltransf_11 PF08241.12 KKK41777.1 - 3.1e-16 59.8 0.0 5.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK41777.1 - 8.7e-12 45.6 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK41777.1 - 1.6e-09 37.5 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KKK41777.1 - 2.5e-09 37.2 0.0 2.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK41777.1 - 3e-09 36.9 0.4 8.6e-09 35.4 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK41777.1 - 1.3e-07 32.2 0.1 3.5e-07 30.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK41777.1 - 0.0015 17.6 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KKK41777.1 - 0.0019 17.8 0.4 0.11 12.0 0.1 2.6 1 1 2 3 3 3 1 Methyltransferase small domain Methyltransf_PK PF05891.12 KKK41777.1 - 0.0091 15.5 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 KKK41777.1 - 0.0093 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KKK41777.1 - 0.058 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase PCMT PF01135.19 KKK41777.1 - 0.079 12.7 0.1 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KKK41777.1 - 0.086 12.1 0.2 0.3 10.3 0.2 1.7 1 1 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KKK41777.1 - 0.086 12.2 0.2 0.12 11.7 0.2 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 KKK41777.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fer4 PF00037.27 KKK41778.1 - 1.4e-09 37.3 9.8 3.3e-05 23.5 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK41778.1 - 3.4e-09 37.2 3.5 4.7e-09 36.7 3.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41778.1 - 7.5e-08 32.1 10.0 0.00012 21.9 1.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK41778.1 - 2.2e-07 31.7 2.5 0.0013 19.6 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK41778.1 - 3e-07 30.4 17.9 5.8e-05 23.1 8.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41778.1 - 9.6e-07 28.9 5.2 1.7e-06 28.1 5.2 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41778.1 - 1.8e-06 28.0 2.4 0.00056 20.0 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK41778.1 - 9.2e-05 22.3 10.4 0.00046 20.1 2.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KKK41778.1 - 0.0037 18.1 12.9 0.32 12.0 3.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KKK41778.1 - 0.02 15.7 6.6 0.065 14.1 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK41778.1 - 0.02 15.4 9.7 0.23 12.1 1.5 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain CpXC PF14353.6 KKK41778.1 - 0.081 13.0 2.7 0.1 12.6 2.7 1.2 1 0 0 1 1 1 0 CpXC protein Fer4_17 PF13534.6 KKK41778.1 - 0.5 10.9 9.8 3.6 8.2 3.3 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK41778.1 - 0.59 10.6 10.3 1.1 9.8 3.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain zf-C4_Topoisom PF01396.19 KKK41782.1 - 0.01 15.6 0.1 0.013 15.3 0.1 1.2 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.6 KKK41782.1 - 0.05 13.0 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain MethyltransfD12 PF02086.15 KKK41784.1 - 0.0027 17.4 3.7 0.12 12.1 0.1 2.4 2 1 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase DUF3800 PF12686.7 KKK41785.1 - 1.5e-05 25.6 1.6 1.8e-05 25.4 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3800) DUF2779 PF11074.8 KKK41785.1 - 0.018 15.5 0.4 0.022 15.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) DUF3800 PF12686.7 KKK41786.1 - 1.6e-07 32.0 0.6 3.2e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3800) Ribosomal_L10 PF00466.20 KKK41786.1 - 0.079 13.1 0.0 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L10 Terminase_5 PF06056.12 KKK41787.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Methyltransf_23 PF13489.6 KKK41788.1 - 8.2e-10 38.8 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK41788.1 - 1.2e-07 31.7 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK41788.1 - 4.5e-07 30.5 0.0 7.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK41788.1 - 3.7e-06 27.5 0.0 6.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KKK41788.1 - 0.00034 20.3 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 KKK41788.1 - 0.0004 21.1 0.0 0.00092 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK41788.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Phage_mat-A PF03863.13 KKK41788.1 - 0.002 17.1 0.0 0.0024 16.9 0.0 1.1 1 0 0 1 1 1 1 Phage maturation protein Methyltransf_9 PF08003.11 KKK41788.1 - 0.022 13.7 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MFS_1 PF07690.16 KKK41789.1 - 2.7e-09 36.4 42.6 3.1e-07 29.6 11.4 3.1 1 1 3 4 4 4 3 Major Facilitator Superfamily zinc_ribbon_10 PF10058.9 KKK41790.1 - 0.04 13.6 0.5 0.07 12.9 0.5 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Kinase-PolyVal PF18762.1 KKK41790.1 - 0.058 13.3 0.6 0.078 12.9 0.6 1.2 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins HAUS5 PF14817.6 KKK41791.1 - 0.046 12.5 1.0 0.052 12.3 1.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 HTH_38 PF13936.6 KKK41792.1 - 0.0013 18.4 2.8 0.53 10.1 0.2 3.1 2 1 1 3 3 3 2 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KKK41792.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 MetOD2 PF18548.1 KKK41792.1 - 0.079 13.1 0.6 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 Metanogen output domain 2 TMEM237 PF15383.6 KKK41794.1 - 0.088 11.9 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 TypeIII_RM_meth PF12564.8 KKK41794.1 - 0.11 12.7 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit DUF5069 PF16798.5 KKK41795.1 - 0.064 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) LRR_8 PF13855.6 KKK41797.1 - 2e-22 78.7 38.2 1.1e-06 28.3 0.4 4.9 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 KKK41797.1 - 2.1e-18 66.1 22.5 3.9e-06 27.1 0.8 6.0 3 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 KKK41797.1 - 0.0016 18.4 1.6 0.12 12.4 0.1 2.7 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 KKK41797.1 - 0.0019 18.5 15.4 5.2 8.0 0.2 7.4 4 4 1 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KKK41797.1 - 0.095 12.8 3.6 16 5.9 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat Fer4 PF00037.27 KKK41798.1 - 5.1e-17 60.9 32.1 3.6e-06 26.5 3.2 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_7 PF12838.7 KKK41798.1 - 1.4e-13 51.2 15.8 0.00029 21.4 0.2 3.7 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41798.1 - 5e-12 45.8 23.7 0.0003 20.9 3.7 3.5 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41798.1 - 1.9e-11 43.5 28.1 6.6e-05 22.8 2.9 4.2 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_10 PF13237.6 KKK41798.1 - 2.4e-11 43.6 18.8 0.0018 18.4 0.3 3.5 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41798.1 - 2.6e-09 37.1 21.8 1.4e-05 25.2 8.5 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK41798.1 - 7.6e-09 36.4 17.8 0.0072 17.2 0.3 3.7 3 0 0 3 3 3 3 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK41798.1 - 9.9e-09 35.5 15.1 1.2e-05 25.6 7.3 3.0 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41798.1 - 3.8e-07 30.6 12.1 6.1e-06 26.7 6.7 3.0 4 0 0 4 4 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK41798.1 - 6.4e-07 29.1 27.3 0.02 15.0 2.0 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_4 PF12800.7 KKK41798.1 - 0.00066 20.0 27.6 0.25 11.9 1.8 4.2 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_13 PF13370.6 KKK41798.1 - 0.0021 18.6 19.6 0.092 13.3 0.8 3.6 3 0 0 3 3 3 3 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KKK41798.1 - 0.0082 16.9 20.9 0.41 11.4 0.4 3.8 4 0 0 4 4 3 2 4Fe-4S single cluster domain Fer4_22 PF17179.4 KKK41798.1 - 6.1 7.8 22.9 0.83 10.5 1.0 4.4 4 1 2 6 6 6 0 4Fe-4S dicluster domain NAD_binding_8 PF13450.6 KKK41799.1 - 9.5e-10 38.6 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK41799.1 - 2.1e-08 34.6 0.3 3.1e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK41799.1 - 5.4e-08 32.6 0.2 9.7e-08 31.8 0.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK41799.1 - 1.5e-07 30.9 0.3 2.1e-07 30.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK41799.1 - 3e-07 30.4 0.3 4.8e-07 29.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK41799.1 - 4.8e-07 29.3 0.1 8.9e-07 28.4 0.1 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK41799.1 - 3.5e-06 26.0 0.2 4.7e-06 25.6 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KKK41799.1 - 3.3e-05 23.4 0.0 5.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KKK41799.1 - 6.6e-05 22.3 0.4 0.00011 21.6 0.3 1.4 1 1 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KKK41799.1 - 7.1e-05 22.2 0.7 0.00028 20.2 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KKK41799.1 - 0.00012 21.3 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK41799.1 - 0.00014 21.2 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK41799.1 - 0.002 18.1 0.1 0.0039 17.2 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KKK41799.1 - 0.0033 16.8 0.1 0.0043 16.4 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 KKK41799.1 - 0.0049 15.4 0.0 0.0068 14.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 KKK41799.1 - 0.018 14.9 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KKK41799.1 - 0.061 12.4 0.2 0.09 11.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KKK41799.1 - 0.071 13.6 0.1 0.18 12.3 0.1 1.7 1 1 1 2 2 2 0 Putative NAD(P)-binding DNA_III_psi PF03603.13 KKK41799.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III psi subunit MCRA PF06100.11 KKK41799.1 - 0.21 10.3 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 MCRA family DUF3493 PF11998.8 KKK41800.1 - 0.027 14.6 0.5 0.054 13.7 0.5 1.4 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 OST3_OST6 PF04756.13 KKK41800.1 - 0.12 11.7 1.8 0.17 11.2 1.8 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family OMPdecase PF00215.24 KKK41801.1 - 0.0029 17.2 0.0 0.0036 16.9 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NnrS PF05940.12 KKK41805.1 - 0.0005 19.6 11.7 0.00061 19.3 11.7 1.1 1 0 0 1 1 1 1 NnrS protein DUF373 PF04123.13 KKK41805.1 - 1.7 8.0 22.5 1.4 8.3 7.6 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF373) Acetyltransf_10 PF13673.7 KKK41806.1 - 0.026 14.4 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CarS-like PF01864.17 KKK41806.1 - 0.029 14.3 0.0 0.075 13.0 0.0 1.6 2 0 0 2 2 2 0 CDP-archaeol synthase GFO_IDH_MocA PF01408.22 KKK41808.1 - 2.9e-23 83.0 0.5 4e-23 82.5 0.5 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK41808.1 - 1.1e-06 28.6 0.0 3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ox_reductase_C PF08635.10 KKK41808.1 - 0.0011 18.6 0.0 0.058 13.1 0.0 3.0 4 0 0 4 4 4 1 Putative oxidoreductase C terminal domain NAD_binding_3 PF03447.16 KKK41808.1 - 0.021 15.5 0.4 0.031 14.9 0.4 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DDE_Tnp_1 PF01609.21 KKK41809.1 - 1.1e-08 35.0 4.6 1.1e-08 35.0 4.6 2.7 1 1 1 2 2 2 1 Transposase DDE domain DUF496 PF04363.12 KKK41809.1 - 0.023 14.7 3.5 3.6 7.7 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF496) DUF2695 PF10905.8 KKK41811.1 - 5e-05 23.4 0.2 0.00011 22.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2695) SKI PF01202.22 KKK41813.1 - 9e-38 129.9 0.2 1e-37 129.7 0.2 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 KKK41813.1 - 5.2e-06 27.0 0.1 7.8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 KKK41813.1 - 0.0033 16.8 0.6 0.0046 16.3 0.6 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_17 PF13207.6 KKK41813.1 - 0.0039 17.6 0.3 0.048 14.1 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK41813.1 - 0.006 16.7 0.0 0.011 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 KKK41813.1 - 0.0062 16.6 0.2 0.02 15.0 0.2 1.9 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA PF00004.29 KKK41813.1 - 0.0085 16.5 0.3 0.021 15.3 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK41813.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flavin_Reduct PF01613.18 KKK41814.1 - 7.8e-25 87.7 0.0 8.6e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Shikimate_dh_N PF08501.11 KKK41815.1 - 5.9e-30 103.4 0.0 1.3e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KKK41815.1 - 3.1e-10 39.6 0.1 6.6e-10 38.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KKK41815.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KKK41815.1 - 0.00029 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KKK41815.1 - 0.0012 18.2 0.0 0.0092 15.3 0.0 2.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.25 KKK41815.1 - 0.015 14.8 0.4 0.2 11.1 0.0 2.6 3 0 0 3 3 3 0 short chain dehydrogenase NAD_Gly3P_dh_N PF01210.23 KKK41815.1 - 0.061 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 KKK41815.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KKK41815.1 - 0.071 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF362 PF04015.12 KKK41816.1 - 5.8e-38 131.2 0.0 7.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF362) DUF2717 PF10911.8 KKK41816.1 - 0.12 12.0 0.1 0.43 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) DZR PF12773.7 KKK41817.1 - 2.5e-08 33.8 3.5 0.00012 22.0 0.4 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_9 PF14369.6 KKK41817.1 - 4.4e-05 23.6 3.8 0.06 13.6 0.5 3.2 3 0 0 3 3 3 2 zinc-ribbon zf-LITAF-like PF10601.9 KKK41817.1 - 0.00013 22.1 2.9 0.00013 22.1 2.9 3.1 2 1 1 3 3 3 1 LITAF-like zinc ribbon domain zinc_ribbon_15 PF17032.5 KKK41817.1 - 0.00031 21.4 8.2 0.0076 17.0 5.4 2.3 2 1 0 2 2 2 1 zinc-ribbon family Nudix_N_2 PF14803.6 KKK41817.1 - 0.0037 17.1 12.9 0.76 9.7 0.1 3.9 4 0 0 4 4 4 3 Nudix N-terminal zf-ribbon_3 PF13248.6 KKK41817.1 - 0.015 14.7 2.9 0.015 14.7 2.9 3.4 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 KKK41817.1 - 0.041 13.9 7.5 0.096 12.7 0.6 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KKK41817.1 - 0.11 12.3 19.0 0.24 11.2 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain GFA PF04828.14 KKK41817.1 - 0.12 12.7 12.0 0.047 14.0 2.3 3.0 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF5472 PF17566.2 KKK41817.1 - 0.34 10.9 6.1 0.86 9.6 1.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5472) Zn-ribbon_8 PF09723.10 KKK41817.1 - 0.93 9.7 8.4 0.8 9.9 1.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain MqsA_antitoxin PF15731.5 KKK41817.1 - 1.3 9.2 4.7 2.1 8.4 0.7 2.9 2 1 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HscB_4_cys PF18256.1 KKK41817.1 - 2.2 8.2 8.3 1.1 9.1 1.3 2.8 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Rdx PF10262.9 KKK41817.1 - 2.3 8.4 5.4 6.1 7.1 0.1 2.7 3 0 0 3 3 3 0 Rdx family zf-FCS PF06467.14 KKK41817.1 - 6.7 6.7 14.3 0.43 10.6 2.6 3.1 3 1 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF2367 PF10164.9 KKK41817.1 - 8.3 7.0 10.8 0.15 12.6 0.8 2.5 2 1 0 3 3 2 0 Uncharacterized conserved protein (DUF2367) PhnA_Zn_Ribbon PF08274.12 KKK41817.1 - 9.4 6.3 12.2 9.7 6.2 0.6 3.8 4 0 0 4 4 4 0 PhnA Zinc-Ribbon DZR PF12773.7 KKK41818.1 - 1.2e-08 34.8 1.4 3e-06 27.1 1.4 2.5 1 1 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK41818.1 - 4.7e-08 32.2 11.7 4.9e-05 22.6 2.9 3.2 3 0 0 3 3 3 3 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK41818.1 - 3.4e-07 29.8 14.2 9.3e-06 25.2 5.2 3.3 3 0 0 3 3 3 2 zinc-ribbon domain Nudix_N_2 PF14803.6 KKK41818.1 - 4.9e-05 23.1 10.9 0.23 11.4 0.2 4.0 4 0 0 4 4 4 2 Nudix N-terminal zinc_ribbon_15 PF17032.5 KKK41818.1 - 6.7e-05 23.6 7.5 0.001 19.8 7.5 2.3 1 1 0 1 1 1 1 zinc-ribbon family DNA_ligase_ZBD PF03119.16 KKK41818.1 - 6.7e-05 22.8 2.1 0.64 10.1 0.1 3.6 3 0 0 3 3 3 1 NAD-dependent DNA ligase C4 zinc finger domain zinc-ribbons_6 PF07191.12 KKK41818.1 - 0.00095 19.1 6.5 0.59 10.2 0.8 3.5 3 1 0 3 3 3 1 zinc-ribbons zf-NADH-PPase PF09297.11 KKK41818.1 - 0.0014 18.2 9.1 0.66 9.7 0.1 3.9 4 0 0 4 4 4 2 NADH pyrophosphatase zinc ribbon domain zf-LITAF-like PF10601.9 KKK41818.1 - 0.0016 18.7 10.3 0.35 11.2 1.9 3.0 2 2 0 2 2 2 2 LITAF-like zinc ribbon domain DUF2089 PF09862.9 KKK41818.1 - 0.012 15.7 3.7 4.5 7.3 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2089) zf-C4_Topoisom PF01396.19 KKK41818.1 - 0.014 15.2 9.6 1.8 8.4 0.1 3.8 4 0 0 4 4 4 0 Topoisomerase DNA binding C4 zinc finger YhfH PF14149.6 KKK41818.1 - 0.021 14.8 7.2 5.1 7.2 0.0 3.6 4 0 0 4 4 3 0 YhfH-like protein DUF1272 PF06906.11 KKK41818.1 - 0.024 14.7 6.2 0.7 10.0 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) C1_1 PF00130.22 KKK41818.1 - 0.025 14.5 2.8 2.1 8.3 0.1 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L33 PF00471.20 KKK41818.1 - 0.027 14.9 2.3 13 6.3 0.0 3.3 3 1 0 3 3 3 0 Ribosomal protein L33 Zn-ribbon_8 PF09723.10 KKK41818.1 - 0.029 14.5 7.8 3.2 8.0 2.3 4.0 3 1 1 4 4 4 0 Zinc ribbon domain Cript PF10235.9 KKK41818.1 - 0.078 13.6 5.0 0.62 10.7 0.2 2.9 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT zf-dskA_traR PF01258.17 KKK41818.1 - 0.1 12.6 10.4 12 5.9 0.0 4.0 3 1 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Prok-RING_1 PF14446.6 KKK41818.1 - 0.13 12.2 11.2 0.14 12.1 1.2 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 KKK41818.1 - 0.2 11.6 9.7 0.27 11.1 0.8 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) YacG PF03884.14 KKK41818.1 - 0.2 11.4 7.5 6.9 6.5 1.3 3.5 3 1 0 3 3 3 0 DNA gyrase inhibitor YacG GFA PF04828.14 KKK41818.1 - 0.21 11.9 6.8 22 5.4 0.0 3.9 2 1 2 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 KKK41818.1 - 0.22 11.2 9.6 6.6 6.4 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-ISL3 PF14690.6 KKK41818.1 - 0.23 12.2 9.6 4.3 8.1 0.4 3.7 3 1 1 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.7 KKK41818.1 - 0.39 10.7 8.7 14 5.7 0.6 4.0 3 1 1 4 4 4 0 Transposase zinc-ribbon domain FANCL_C PF11793.8 KKK41818.1 - 0.72 10.1 9.3 9.7 6.5 0.1 3.9 3 1 1 4 4 4 0 FANCL C-terminal domain HypA PF01155.19 KKK41818.1 - 0.9 9.6 7.1 1.8 8.6 2.8 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_2 PF03107.16 KKK41818.1 - 0.95 9.8 6.9 9 6.7 0.7 2.7 3 0 0 3 3 2 0 C1 domain DNA_RNApol_7kD PF03604.13 KKK41818.1 - 1 9.1 11.4 17 5.2 0.8 3.8 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF35_N PF12172.8 KKK41818.1 - 1 9.3 4.5 6.5 6.7 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2116 PF09889.9 KKK41818.1 - 1.1 9.3 9.3 9.4 6.3 1.3 3.5 3 1 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Zn_ribbon_17 PF17120.5 KKK41818.1 - 1.4 8.6 5.2 11 5.7 0.6 2.8 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Cys_rich_CPXG PF14255.6 KKK41818.1 - 1.5 8.8 8.0 4.6 7.2 0.1 3.6 3 1 1 4 4 4 0 Cysteine-rich CPXCG TackOD1 PF18551.1 KKK41818.1 - 1.7 8.3 6.0 1.7 8.3 0.6 2.3 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 DUF2367 PF10164.9 KKK41818.1 - 1.9 9.0 12.5 0.077 13.5 2.3 2.8 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2367) TF_Zn_Ribbon PF08271.12 KKK41818.1 - 2.8 7.6 14.3 2.2 7.9 1.0 3.6 3 1 1 4 4 4 0 TFIIB zinc-binding zf-met PF12874.7 KKK41818.1 - 4.1 7.9 6.4 7.3 7.1 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Prok-RING_4 PF14447.6 KKK41818.1 - 4.8 7.1 8.7 18 5.3 0.1 3.7 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 KKK41818.1 - 5.6 7.3 7.7 41 4.6 0.1 3.6 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DUF2321 PF10083.9 KKK41818.1 - 5.9 6.5 7.4 2.1 8.0 0.8 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) NOB1_Zn_bind PF08772.11 KKK41818.1 - 6.3 7.0 15.2 5 7.4 0.3 3.6 3 1 1 4 4 3 0 Nin one binding (NOB1) Zn-ribbon like zf-IS66 PF13005.7 KKK41818.1 - 8.1 6.9 9.5 43 4.6 0.1 3.7 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Sgf11 PF08209.11 KKK41818.1 - 9 6.0 13.4 21 4.8 0.5 4.3 5 0 0 5 5 5 0 Sgf11 (transcriptional regulation protein) Thymidylate_kin PF02223.17 KKK41819.1 - 8.5e-46 156.0 0.1 9.8e-46 155.8 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 KKK41819.1 - 0.00027 21.5 0.0 0.00043 20.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK41819.1 - 0.00059 20.1 0.0 0.00072 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain PPK2 PF03976.14 KKK41819.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Aconitase PF00330.20 KKK41820.1 - 8.6e-101 338.2 0.4 7.6e-99 331.8 0.4 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 KKK41820.1 - 0.0016 17.3 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Aconitase_C PF00694.19 KKK41821.1 - 6.2e-17 62.2 0.0 8.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KKK41821.1 - 3.4e-05 23.6 0.0 0.00056 19.6 0.0 2.0 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus HD PF01966.22 KKK41822.1 - 6.9e-13 48.9 0.3 1.1e-12 48.2 0.3 1.4 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 KKK41822.1 - 0.00057 19.4 0.0 0.0071 15.8 0.0 2.0 1 1 1 2 2 2 1 HDOD domain Gly-zipper_YMGG PF13441.6 KKK41823.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KKK41823.1 - 0.053 13.5 1.0 0.053 13.5 1.0 2.1 2 0 0 2 2 2 0 Glycine zipper HILPDA PF15220.6 KKK41823.1 - 0.087 13.0 1.0 0.26 11.5 0.6 2.0 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated Ribosomal_S2 PF00318.20 KKK41824.1 - 3.3e-25 88.6 2.6 2.1e-12 46.8 0.0 2.5 2 1 1 3 3 3 2 Ribosomal protein S2 HAD_2 PF13419.6 KKK41826.1 - 4.2e-23 82.3 0.0 4.8e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK41826.1 - 1.6e-08 34.5 0.0 2.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK41826.1 - 1.8e-08 34.9 0.0 2.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK41826.1 - 0.0076 16.7 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKK41826.1 - 0.015 14.7 0.0 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 Putative Phosphatase Acetyltransf_1 PF00583.25 KKK41827.1 - 4.8e-14 52.6 0.0 5.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK41827.1 - 3.4e-12 46.6 0.0 5.1e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK41827.1 - 1e-08 35.2 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK41827.1 - 5e-07 29.6 0.0 7.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KKK41827.1 - 1.2e-06 28.6 0.0 1.6e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KKK41827.1 - 0.0023 17.5 0.0 0.004 16.8 0.0 1.4 2 0 0 2 2 2 1 GNAT acetyltransferase Acetyltransf_3 PF13302.7 KKK41827.1 - 0.024 15.3 0.0 0.028 15.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK41827.1 - 0.14 12.3 0.0 0.93 9.7 0.0 2.1 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase Glycophorin_A PF01102.18 KKK41829.1 - 0.029 14.6 9.9 1.3 9.3 3.4 2.8 2 2 0 2 2 2 0 Glycophorin A DPM3 PF08285.11 KKK41829.1 - 1.3 9.2 5.7 0.17 12.1 0.7 2.1 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CbiA PF01656.23 KKK41830.1 - 9.3e-09 35.4 0.0 1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKK41830.1 - 7.2e-08 32.5 0.1 7.6e-08 32.5 0.1 1.0 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KKK41830.1 - 1.1e-07 31.3 0.1 1.4e-07 31.0 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 KKK41830.1 - 0.00011 21.8 2.1 0.00014 21.4 2.1 1.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DUF87 PF01935.17 KKK41830.1 - 0.00031 20.9 0.1 0.00039 20.6 0.1 1.1 1 0 0 1 1 1 1 Helicase HerA, central domain MeaB PF03308.16 KKK41830.1 - 0.0018 17.4 0.0 0.0019 17.2 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 KKK41830.1 - 0.0028 17.2 0.0 0.0029 17.1 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 KKK41830.1 - 0.0031 16.7 0.1 0.0031 16.7 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KKK41830.1 - 0.0068 16.8 0.0 0.0068 16.8 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK41830.1 - 0.009 15.9 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 KKK41830.1 - 0.014 16.0 0.1 0.014 16.0 0.1 1.1 1 0 0 1 1 1 0 ABC transporter CLP1_P PF16575.5 KKK41830.1 - 0.029 14.2 0.1 0.034 14.0 0.1 1.1 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop T2SSE PF00437.20 KKK41830.1 - 0.038 13.0 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein CBP_BcsQ PF06564.12 KKK41830.1 - 0.068 12.6 0.0 0.068 12.6 0.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ MadL PF03817.13 KKK41830.1 - 0.074 13.1 0.7 2.6 8.1 0.1 2.0 2 0 0 2 2 2 0 Malonate transporter MadL subunit AAA_29 PF13555.6 KKK41830.1 - 0.088 12.6 0.5 0.13 12.0 0.5 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KKK41830.1 - 0.1 12.6 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KKK41830.1 - 0.13 11.5 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 KAP family P-loop domain Pribosyltran_N PF13793.6 KKK41834.1 - 1.5e-16 60.4 0.0 1.6e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase MoaE PF02391.17 KKK41835.1 - 5.2e-23 81.5 0.3 6.4e-23 81.2 0.3 1.1 1 0 0 1 1 1 1 MoaE protein ThiS PF02597.20 KKK41836.1 - 7.9e-11 42.5 0.1 9.9e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 ThiS family PRESAN PF09687.10 KKK41836.1 - 0.0011 19.5 1.2 0.0012 19.4 1.2 1.1 1 0 0 1 1 1 1 Plasmodium RESA N-terminal TSP9 PF11493.8 KKK41836.1 - 0.039 14.6 0.0 0.066 13.9 0.0 1.4 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 SepSecS PF05889.13 KKK41836.1 - 0.13 10.9 0.1 0.14 10.8 0.1 1.0 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Radical_SAM PF04055.21 KKK41837.1 - 1.2e-27 97.3 0.1 1.9e-27 96.7 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Mob_synth_C PF06463.13 KKK41837.1 - 6.2e-16 58.5 0.9 1.7e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Fer4_14 PF13394.6 KKK41837.1 - 1.5e-08 34.8 1.3 1.5e-08 34.8 1.3 2.1 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK41837.1 - 1e-06 29.0 0.6 2.7e-06 27.7 0.6 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain MoaC PF01967.21 KKK41838.1 - 9.9e-47 158.4 1.3 1.2e-46 158.2 1.3 1.0 1 0 0 1 1 1 1 MoaC family Sigma70_r2 PF04542.14 KKK41839.1 - 0.0032 17.2 0.1 0.88 9.4 0.0 2.8 3 0 0 3 3 3 2 Sigma-70 region 2 ABC_tran PF00005.27 KKK41840.1 - 8.8e-30 104.0 0.1 1.8e-29 103.0 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KKK41840.1 - 7.5e-14 52.2 0.3 2.4e-06 27.6 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKK41840.1 - 1e-06 28.7 0.1 0.00011 22.1 0.2 2.1 1 1 1 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KKK41840.1 - 2.4e-05 23.9 0.2 0.023 14.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK41840.1 - 0.00016 22.2 1.3 0.0011 19.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK41840.1 - 0.00059 20.3 0.1 0.0015 18.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK41840.1 - 0.0013 19.0 0.1 0.014 15.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK41840.1 - 0.0088 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 KKK41840.1 - 0.0092 15.6 0.3 0.031 13.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KKK41840.1 - 0.013 14.2 0.1 0.11 11.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KKK41840.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 KKK41840.1 - 0.038 14.2 0.1 0.12 12.7 0.1 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KKK41840.1 - 0.14 12.7 0.5 0.34 11.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK41840.1 - 0.14 12.2 0.2 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ferrochelatase PF00762.19 KKK41842.1 - 3.6e-08 32.9 0.0 2.5e-06 26.8 0.0 2.5 2 1 0 2 2 2 2 Ferrochelatase Cu2_monoox_C PF03712.15 KKK41842.1 - 0.11 12.0 0.3 8.3 5.9 0.1 2.2 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain POR_N PF01855.19 KKK41846.1 - 3.4e-49 167.7 0.3 4e-49 167.5 0.3 1.0 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KKK41847.1 - 6.3e-23 81.7 0.1 8.5e-23 81.3 0.1 1.2 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4 PF00037.27 KKK41847.1 - 3.2e-10 39.4 10.5 8.1e-05 22.3 1.1 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK41847.1 - 1.4e-07 31.5 5.1 1.4e-07 31.5 5.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41847.1 - 4.9e-06 26.6 7.7 0.025 14.7 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK41847.1 - 1.6e-05 25.8 12.4 0.021 15.8 5.3 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK41847.1 - 5.4e-05 23.7 9.9 0.01 16.4 12.6 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41847.1 - 0.00012 22.2 13.2 0.0002 21.4 11.5 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK41847.1 - 0.00017 22.1 9.7 0.0033 17.9 0.6 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_6 PF12837.7 KKK41847.1 - 0.0015 18.5 13.4 0.013 15.6 1.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK41847.1 - 0.011 15.8 13.7 0.19 11.9 1.5 2.8 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK41847.1 - 0.08 13.1 5.0 4 7.7 1.5 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK41847.1 - 0.14 12.7 11.1 1.9 9.2 1.8 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain MTHFR_C PF12225.8 KKK41847.1 - 0.24 11.0 7.4 0.26 11.0 1.4 2.4 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal Fer4_17 PF13534.6 KKK41847.1 - 0.27 11.8 8.2 1.9 9.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK41847.1 - 0.76 10.6 11.5 23 5.8 11.5 2.9 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_8 PF13183.6 KKK41847.1 - 1.8 9.0 14.9 11 6.5 4.0 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain Peptidase_M28 PF04389.17 KKK41848.1 - 0.025 14.3 0.0 0.027 14.2 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M28 LapA_dom PF06305.11 KKK41849.1 - 0.043 13.6 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Gram_pos_anchor PF00746.21 KKK41849.1 - 0.67 9.9 3.3 1.3 9.0 3.3 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif MM_CoA_mutase PF01642.22 KKK41850.1 - 5.6e-212 704.8 0.0 6.5e-212 704.6 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase DUF438 PF04282.13 KKK41850.1 - 0.027 14.4 1.3 0.35 10.9 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF438) M60-like_N PF17291.2 KKK41850.1 - 0.096 12.6 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases OB_aCoA_assoc PF01796.17 KKK41851.1 - 4e-07 29.9 0.0 5.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated Ribosomal_L37e PF01907.19 KKK41851.1 - 1.6 8.9 8.7 0.45 10.7 3.0 2.2 1 1 1 2 2 2 0 Ribosomal protein L37e Ras PF00071.22 KKK41852.1 - 7e-32 110.3 0.7 7.9e-32 110.1 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK41852.1 - 3.3e-19 69.3 0.1 5.5e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41852.1 - 5e-09 35.9 0.1 6.2e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 KKK41852.1 - 0.00033 20.5 0.0 0.00038 20.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK41852.1 - 0.00038 20.4 0.0 0.00054 19.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase Gtr1_RagA PF04670.12 KKK41852.1 - 0.00051 19.5 0.3 0.00061 19.2 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KKK41852.1 - 0.00078 18.7 2.5 0.0013 18.0 2.5 1.4 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.27 KKK41852.1 - 0.0013 18.3 0.1 0.0037 16.8 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Xrn1_D3 PF18194.1 KKK41852.1 - 0.1 12.7 0.1 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Ras PF00071.22 KKK41853.1 - 3.5e-42 143.7 0.2 4e-42 143.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK41853.1 - 5.5e-29 100.8 0.0 7.5e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41853.1 - 3.3e-12 46.2 0.0 3.8e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK41853.1 - 4e-07 29.6 0.1 4.4e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK41853.1 - 0.00094 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK41853.1 - 0.0018 17.8 0.9 0.019 14.5 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KKK41853.1 - 0.0075 15.5 7.1 0.078 12.1 2.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.17 KKK41853.1 - 0.011 15.6 0.1 0.037 13.8 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK41853.1 - 0.012 15.5 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 KKK41853.1 - 0.033 13.6 0.0 0.041 13.3 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KKK41853.1 - 0.045 14.1 0.1 0.06 13.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KKK41853.1 - 0.047 14.1 0.0 0.48 10.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KKK41853.1 - 0.17 11.3 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein TPR_2 PF07719.17 KKK41855.1 - 8e-10 38.1 0.0 0.15 12.3 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK41855.1 - 5.2e-09 35.6 7.2 0.014 15.5 0.1 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK41855.1 - 6.3e-09 35.3 1.4 0.49 10.3 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_45 PF14947.6 KKK41855.1 - 3.9e-08 33.2 2.4 0.00067 19.6 0.5 3.4 2 0 0 2 2 2 2 Winged helix-turn-helix TPR_6 PF13174.6 KKK41855.1 - 1.3e-06 28.6 0.0 9.4 7.1 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK41855.1 - 1.7e-05 25.3 0.0 11 7.2 0.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 KKK41855.1 - 8.1e-05 21.7 10.3 0.02 13.8 0.2 3.7 2 1 0 3 3 3 3 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 KKK41855.1 - 0.0001 22.5 0.0 0.2 12.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat HTH_34 PF13601.6 KKK41855.1 - 0.00012 22.2 1.1 0.12 12.6 0.0 3.8 3 1 0 3 3 3 1 Winged helix DNA-binding domain TPR_19 PF14559.6 KKK41855.1 - 0.0002 21.8 0.0 0.89 10.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KKK41855.1 - 0.0027 18.0 0.0 19 5.9 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TrmB PF01978.19 KKK41855.1 - 0.0027 17.6 0.2 4.7 7.2 0.0 2.9 3 0 0 3 3 2 2 Sugar-specific transcriptional regulator TrmB TPR_11 PF13414.6 KKK41855.1 - 0.0035 17.0 1.4 1.1 9.0 0.0 3.4 4 0 0 4 4 4 1 TPR repeat ATP13 PF12921.7 KKK41855.1 - 0.008 16.0 1.2 0.16 11.8 0.2 2.8 2 1 0 2 2 2 1 Mitochondrial ATPase expression PadR PF03551.14 KKK41855.1 - 0.013 15.4 0.1 4.8 7.2 0.0 3.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family MarR PF01047.22 KKK41855.1 - 0.02 14.8 0.0 4.1 7.4 0.0 2.7 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 KKK41855.1 - 0.027 14.5 0.1 6.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain ANAPC5 PF12862.7 KKK41855.1 - 0.033 14.3 0.3 27 4.9 0.0 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_15 PF13429.6 KKK41855.1 - 0.075 12.2 0.1 0.77 8.9 0.0 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat Mrr_N PF14338.6 KKK41855.1 - 0.1 12.8 0.8 3.6 7.8 0.1 3.0 2 0 0 2 2 2 0 Mrr N-terminal domain HTH_5 PF01022.20 KKK41855.1 - 0.16 11.9 0.1 12 5.9 0.0 2.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family TPR_16 PF13432.6 KKK41855.1 - 0.17 12.6 0.0 6.9 7.4 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat MarR_2 PF12802.7 KKK41855.1 - 0.2 11.6 0.0 8.7 6.3 0.0 2.4 2 0 0 2 2 2 0 MarR family ANAPC3 PF12895.7 KKK41855.1 - 0.46 10.7 3.1 4.1 7.7 0.3 3.4 3 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Carboxyl_trans PF01039.22 KKK41856.1 - 2.9e-182 606.7 0.0 3.7e-182 606.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KKK41856.1 - 0.016 14.7 0.7 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) ketoacyl-synt PF00109.26 KKK41857.1 - 4.9e-81 272.0 0.0 1.5e-65 221.3 0.0 3.1 2 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK41857.1 - 9.8e-44 148.2 1.7 4.8e-38 129.8 0.0 2.9 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KKK41857.1 - 5.4e-42 144.4 0.0 1e-41 143.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KKK41857.1 - 5.9e-30 104.5 0.0 1.7e-29 103.0 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KKK41857.1 - 4.5e-29 101.6 0.0 7.2e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KKK41857.1 - 1.4e-27 95.8 5.0 1.5e-05 25.3 0.0 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site NMO PF03060.15 KKK41857.1 - 5.5e-21 75.3 0.0 4.9e-08 32.7 0.0 3.7 2 1 1 3 3 3 3 Nitronate monooxygenase ACPS PF01648.20 KKK41857.1 - 9.4e-18 64.4 0.3 3.1e-11 43.4 0.1 2.9 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 KKK41857.1 - 2e-11 43.7 0.0 5.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK41857.1 - 4.6e-09 36.2 0.0 9.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KAsynt_C_assoc PF16197.5 KKK41857.1 - 2.8e-08 34.2 0.0 2.5e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 KKK41857.1 - 3.7e-08 33.1 4.5 3.5e-05 23.6 0.4 4.0 2 2 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 KKK41857.1 - 2.1e-07 30.6 0.5 0.00023 20.6 0.1 2.5 2 0 0 2 2 2 2 Thiolase, N-terminal domain DUF1493 PF07377.12 KKK41857.1 - 1.4e-05 25.5 11.4 0.47 10.9 0.1 5.6 3 1 1 4 4 4 3 Protein of unknown function (DUF1493) 4PPT_N PF17837.1 KKK41857.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain DUF2200 PF09966.9 KKK41857.1 - 0.98 9.6 9.1 21 5.3 0.0 5.4 6 0 0 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2200) Hydrolase_4 PF12146.8 KKK41858.1 - 9.8e-15 54.5 0.0 5.7e-07 29.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KKK41858.1 - 5e-08 32.7 0.0 7.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KKK41858.1 - 6.4e-07 29.2 0.0 0.0037 16.9 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KKK41858.1 - 1.1e-05 25.1 0.2 0.00027 20.5 0.2 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 KKK41858.1 - 2e-05 23.4 0.1 0.00013 20.8 0.1 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KKK41858.1 - 0.00017 21.3 0.0 0.078 12.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 KKK41858.1 - 0.00024 21.1 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 KKK41858.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1100 PF06500.11 KKK41858.1 - 0.0025 16.7 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Baculo_p33 PF05214.12 KKK41858.1 - 0.042 13.6 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P33 Lipase_3 PF01764.25 KKK41858.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 KKK41858.1 - 0.052 12.0 0.0 0.099 11.1 0.0 1.4 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 KKK41858.1 - 0.077 13.6 0.0 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Biotin_lipoyl PF00364.22 KKK41859.1 - 3.3e-16 58.9 2.0 3.3e-16 58.9 2.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KKK41859.1 - 1.9e-10 40.4 2.1 2.5e-06 27.2 0.1 2.5 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 KKK41859.1 - 7.5e-07 29.8 0.1 0.15 12.8 0.0 3.0 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 KKK41859.1 - 0.003 16.8 0.1 1.8 7.8 0.0 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 KKK41859.1 - 0.007 16.3 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein TBPIP PF07106.13 KKK41859.1 - 0.022 14.7 0.8 0.94 9.5 0.1 2.3 1 1 1 2 2 2 0 TBPIP/Hop2 winged helix domain RnfC_N PF13375.6 KKK41859.1 - 0.035 14.1 0.1 0.073 13.0 0.1 1.7 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 KKK41859.1 - 0.061 13.1 0.3 2.8 7.7 0.0 2.9 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 MetJ PF01340.20 KKK41859.1 - 0.25 11.3 0.1 0.25 11.3 0.1 1.9 2 0 0 2 2 2 0 Met Apo-repressor, MetJ YabP PF07873.11 KKK41859.1 - 0.31 10.9 4.1 1.3 8.8 0.1 2.6 3 0 0 3 3 3 0 YabP family CPSase_L_D2 PF02786.17 KKK41860.1 - 1e-65 221.2 0.0 1.7e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KKK41860.1 - 5.3e-41 139.6 0.0 1.1e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KKK41860.1 - 1e-34 118.9 0.0 1.9e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KKK41860.1 - 1.2e-10 41.2 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KKK41860.1 - 5.1e-08 32.7 0.0 9.3e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KKK41860.1 - 1.8e-05 24.8 0.0 4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KKK41860.1 - 0.0045 16.6 0.0 0.72 9.4 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KKK41860.1 - 0.044 13.2 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 KKK41860.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain BPL_LplA_LipB PF03099.19 KKK41861.1 - 1e-14 54.5 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Thiolase_N PF00108.23 KKK41862.1 - 5.1e-24 85.0 0.2 1.4e-23 83.6 0.2 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK41862.1 - 1.1e-08 34.7 0.1 2.1e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.22 KKK41862.1 - 0.008 16.2 0.1 1.8 8.6 0.0 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KKK41862.1 - 0.0088 15.6 0.8 0.026 14.1 0.8 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KKK41862.1 - 0.097 12.5 0.2 2 8.3 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ETF PF01012.21 KKK41863.1 - 2.8e-38 131.6 0.0 4e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KKK41863.1 - 6.2e-36 122.3 1.4 6.2e-36 122.3 1.4 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain CHZ PF09649.10 KKK41863.1 - 0.16 11.4 0.1 0.55 9.8 0.1 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ ETF PF01012.21 KKK41864.1 - 4.1e-38 131.1 0.0 4.8e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Acyl-CoA_dh_1 PF00441.24 KKK41865.1 - 1.6e-14 54.4 0.1 1.8e-14 54.2 0.1 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 KKK41865.1 - 0.0003 21.1 0.0 0.00035 20.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HEPN PF05168.14 KKK41867.1 - 9.5e-16 58.0 0.1 1.3e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 HEPN domain Pico_P1A PF02226.16 KKK41867.1 - 0.0021 18.0 0.2 0.0042 17.1 0.2 1.5 1 0 0 1 1 1 1 Picornavirus coat protein (VP4) NTP_transf_2 PF01909.23 KKK41868.1 - 3.5e-11 43.2 0.2 1.4e-10 41.3 0.2 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KKK41868.1 - 3.6e-11 43.0 0.7 1.1e-10 41.5 0.7 1.8 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Adenyl_cycl_N PF12633.7 KKK41868.1 - 0.044 13.7 0.0 0.2 11.6 0.0 1.8 1 1 1 2 2 2 0 Adenylate cyclase NT domain DUF4342 PF14242.6 KKK41868.1 - 0.054 13.5 0.5 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) YojJ PF10372.9 KKK41868.1 - 0.067 13.3 0.4 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus HATPase_c PF02518.26 KKK41869.1 - 4.4e-25 88.4 0.3 1.8e-24 86.4 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK41869.1 - 5.3e-12 45.6 0.1 9.7e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KKK41869.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 KKK41869.1 - 0.0012 18.7 1.7 0.0046 16.8 0.3 2.5 2 2 0 2 2 2 1 GHKL domain MMTV_SAg PF01054.17 KKK41869.1 - 0.017 14.7 0.2 0.027 14.0 0.2 1.3 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen HATPase_c_3 PF13589.6 KKK41869.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SirA PF10747.9 KKK41869.1 - 0.037 14.4 0.1 0.079 13.3 0.1 1.5 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA YscJ_FliF PF01514.17 KKK41869.1 - 0.049 13.3 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family NLE PF08154.12 KKK41869.1 - 0.29 11.7 2.7 0.95 10.0 0.9 2.4 1 1 0 2 2 2 0 NLE (NUC135) domain PAS_3 PF08447.12 KKK41870.1 - 2.7e-19 69.2 0.0 1.2e-08 35.1 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KKK41870.1 - 2.1e-15 56.7 0.0 3e-07 30.4 0.0 3.7 3 1 0 3 3 3 2 PAS fold PAS_9 PF13426.7 KKK41870.1 - 9.9e-14 51.5 0.5 1.5e-05 25.2 0.0 4.2 3 1 0 3 3 3 3 PAS domain PAS_8 PF13188.7 KKK41870.1 - 7.6e-11 41.8 0.0 0.0004 20.3 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KKK41870.1 - 1.6e-10 41.2 0.0 0.00082 19.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold Mod_r PF07200.13 KKK41870.1 - 6e-05 23.2 2.7 0.00014 22.0 2.7 1.5 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PAS_7 PF12860.7 KKK41870.1 - 0.019 15.1 2.5 0.24 11.6 0.1 3.3 3 1 0 3 3 3 0 PAS fold OmpH PF03938.14 KKK41870.1 - 0.027 14.8 8.1 0.036 14.4 4.7 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Erf4 PF10256.9 KKK41870.1 - 0.1 12.7 0.1 0.88 9.7 0.0 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Jnk-SapK_ap_N PF09744.9 KKK41870.1 - 0.28 11.4 11.8 0.1 12.8 7.4 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 TPP_enzyme_C PF02775.21 KKK41871.1 - 3.4e-21 75.6 0.0 6.1e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 KKK41871.1 - 3.8e-05 23.7 0.8 7.5e-05 22.8 0.8 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.19 KKK41872.1 - 1.1e-46 159.4 0.1 1.5e-46 159.0 0.1 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KKK41872.1 - 4.6e-06 26.8 0.0 1.2e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_N PF02776.18 KKK41872.1 - 0.00019 21.1 0.4 0.00039 20.1 0.4 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MCPsignal PF00015.21 KKK41876.1 - 1.8e-27 96.2 16.6 7.3e-27 94.3 12.8 2.4 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain T7SS_ESX_EspC PF10824.8 KKK41876.1 - 0.0047 17.4 3.5 0.045 14.2 0.1 2.2 2 0 0 2 2 2 1 Excreted virulence factor EspC, type VII ESX diderm Sec34 PF04136.15 KKK41876.1 - 0.0062 16.4 6.4 0.39 10.6 0.2 2.2 2 0 0 2 2 2 2 Sec34-like family 7TMR-DISM_7TM PF07695.11 KKK41876.1 - 0.012 15.5 10.4 0.016 15.1 10.4 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling Frag1 PF10277.9 KKK41876.1 - 0.02 14.5 5.4 0.027 14.0 5.4 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family RIC3 PF15361.6 KKK41876.1 - 0.02 15.3 1.7 5.8 7.3 1.3 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 PulG PF11773.8 KKK41876.1 - 0.047 13.5 1.0 0.047 13.5 1.0 2.1 3 0 0 3 3 2 0 Type II secretory pathway pseudopilin DUF948 PF06103.11 KKK41876.1 - 0.082 13.2 0.2 0.082 13.2 0.2 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) H-kinase_dim PF02895.14 KKK41876.1 - 0.084 13.3 3.8 4.6 7.7 0.8 2.4 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Laminin_II PF06009.12 KKK41876.1 - 0.54 10.3 13.5 0.34 10.9 1.3 2.3 2 0 0 2 2 2 0 Laminin Domain II PhageMin_Tail PF10145.9 KKK41876.1 - 0.55 10.0 10.3 4.3 7.1 10.3 2.0 1 1 0 1 1 1 0 Phage-related minor tail protein DUF1216 PF06746.11 KKK41876.1 - 1.4 8.9 7.9 5.6 7.0 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) BLOC1_2 PF10046.9 KKK41876.1 - 1.8 8.9 8.8 3.2 8.1 0.2 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2304 PF10066.9 KKK41876.1 - 7.5 6.8 14.0 20 5.4 14.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF2985 PF11204.8 KKK41877.1 - 0.51 10.5 11.8 3.5 7.8 1.5 4.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2985) Vpu PF00558.19 KKK41877.1 - 0.92 9.3 0.0 0.92 9.3 0.0 2.3 2 0 0 2 2 2 0 Vpu protein Polyketide_cyc2 PF10604.9 KKK41878.1 - 9.8e-05 22.6 0.0 0.00011 22.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Mad3_BUB1_I PF08311.12 KKK41879.1 - 0.045 13.7 0.5 0.1 12.6 0.3 1.7 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 DNA_pol_B PF00136.21 KKK41880.1 - 1.7e-49 168.8 5.3 3e-49 168.0 5.3 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKK41880.1 - 1.2e-32 113.4 3.2 1.2e-32 113.4 3.2 2.2 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 KKK41880.1 - 0.0006 19.8 0.9 0.0026 17.8 0.1 2.4 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KKK41880.1 - 0.0051 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF1722 PF08349.11 KKK41880.1 - 0.018 15.3 0.7 0.059 13.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) AbiEi_4 PF13338.6 KKK41880.1 - 0.14 12.3 0.1 0.47 10.6 0.1 1.9 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HMMR_C PF15908.5 KKK41881.1 - 0.077 13.3 0.8 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Peptidase_M19 PF01244.21 KKK41882.1 - 1.7e-88 296.9 0.0 2e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF3666 PF12408.8 KKK41883.1 - 0.022 14.0 0.0 4.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase Epimerase PF01370.21 KKK41884.1 - 1.2e-19 70.8 0.1 3e-19 69.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK41884.1 - 2.7e-13 50.0 0.1 2.5e-10 40.3 0.1 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK41884.1 - 4.1e-13 49.0 0.0 8.2e-13 48.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKK41884.1 - 6e-11 42.6 0.0 8.7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KKK41884.1 - 4.5e-08 32.9 0.0 8.1e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KKK41884.1 - 6.4e-07 28.8 0.1 5.2e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein CdvA PF18822.1 KKK41884.1 - 0.01 15.6 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain KR PF08659.10 KKK41884.1 - 0.04 13.8 0.1 1.2 9.1 0.1 2.3 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KKK41884.1 - 0.049 14.1 0.1 0.35 11.3 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KKK41884.1 - 0.05 13.0 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 KKK41884.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.23 KKK41884.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KKK41885.1 - 1.8e-36 125.4 0.0 1.3e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK41885.1 - 6.9e-25 88.0 0.0 1.1e-14 54.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK41885.1 - 3.8e-05 23.7 0.0 8.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KKK41886.1 - 9.7e-44 149.2 5.7 3.4e-42 144.1 3.2 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KKK41886.1 - 4.5e-33 114.7 1.3 4.8e-33 114.7 0.5 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK41886.1 - 1.9e-07 31.2 0.4 3.8e-07 30.2 0.3 1.4 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KKK41886.1 - 0.0029 17.5 0.8 0.0029 17.5 0.8 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK41886.1 - 0.0044 16.4 0.4 0.0075 15.6 0.4 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UPF0147 PF03685.13 KKK41886.1 - 0.015 15.3 0.2 0.035 14.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Epimerase PF01370.21 KKK41886.1 - 0.028 13.9 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SurA_N_3 PF13624.6 KKK41886.1 - 0.07 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 SurA N-terminal domain PhoU PF01895.19 KKK41887.1 - 2.4e-22 79.2 10.6 2.1e-20 72.9 1.4 2.4 2 0 0 2 2 2 2 PhoU domain MazE_antitoxin PF04014.18 KKK41887.1 - 1.7e-07 31.0 0.1 4.1e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PspA_IM30 PF04012.12 KKK41887.1 - 0.0019 17.8 1.5 0.08 12.5 0.0 2.5 2 1 0 2 2 2 1 PspA/IM30 family Phosphodiest PF01663.22 KKK41888.1 - 4.4e-28 98.9 1.0 2.7e-25 89.7 0.0 2.7 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KKK41888.1 - 4.2e-08 33.0 0.0 5.3e-05 22.7 0.0 3.2 3 0 0 3 3 3 3 Sulfatase Fibin PF15819.5 KKK41888.1 - 0.12 12.1 0.2 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 Fin bud initiation factor homologue DUF1501 PF07394.12 KKK41888.1 - 0.22 10.5 0.0 0.34 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) ECH_1 PF00378.20 KKK41893.1 - 5.4e-10 39.0 0.1 6e-10 38.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK41893.1 - 0.01 15.3 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Phage_integrase PF00589.22 KKK41894.1 - 2.5e-08 33.9 0.1 5.1e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Phage integrase family bZIP_1 PF00170.21 KKK41894.1 - 0.074 13.2 0.2 0.074 13.2 0.2 2.7 3 0 0 3 3 3 0 bZIP transcription factor OxoGdeHyase_C PF16870.5 KKK41895.1 - 0.019 14.6 0.4 0.021 14.5 0.4 1.1 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal PAS_9 PF13426.7 KKK41896.1 - 2.1e-25 89.0 0.7 2.7e-14 53.3 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS_8 PF13188.7 KKK41896.1 - 5e-17 61.5 0.0 0.00052 20.0 0.0 3.5 3 0 0 3 3 3 3 PAS domain HATPase_c PF02518.26 KKK41896.1 - 1.8e-16 60.6 0.2 6.1e-16 58.9 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 KKK41896.1 - 5.9e-15 55.5 0.0 4.3e-08 33.4 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KKK41896.1 - 8.7e-15 54.7 0.0 6.7e-08 32.5 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.12 KKK41896.1 - 1.9e-14 53.7 0.0 1e-07 32.2 0.0 3.0 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 KKK41896.1 - 9.7e-06 25.5 0.6 2.8e-05 24.1 0.6 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 KKK41896.1 - 0.00036 20.4 1.1 0.00036 20.4 1.1 2.5 3 0 0 3 3 3 1 GHKL domain PAS_7 PF12860.7 KKK41896.1 - 0.11 12.7 0.0 4 7.6 0.0 3.3 4 0 0 4 4 4 0 PAS fold Response_reg PF00072.24 KKK41897.1 - 3.7e-20 72.2 0.4 4.3e-20 72.0 0.4 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PIN_4 PF13638.6 KKK41897.1 - 0.022 15.1 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 PIN domain UPF0160 PF03690.13 KKK41897.1 - 0.029 14.0 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) DUF374 PF04028.13 KKK41897.1 - 0.072 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF374) FMN_red PF03358.15 KKK41898.1 - 5e-05 23.1 0.0 5.4e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKK41898.1 - 0.034 13.9 0.0 0.036 13.8 0.0 1.0 1 0 0 1 1 1 0 Flavodoxin-like fold PALP PF00291.25 KKK41900.1 - 1.7e-78 264.0 0.0 1.9e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Invasin_D3 PF09134.10 KKK41904.1 - 0.00058 20.1 0.9 1.1 9.6 0.1 3.8 2 1 1 3 3 3 2 Invasin, domain 3 Tri3 PF07428.11 KKK41905.1 - 0.075 11.9 0.0 0.08 11.8 0.0 1.0 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 SRR PF07709.11 KKK41905.1 - 0.88 10.2 4.0 3.3 8.5 0.6 2.7 2 0 0 2 2 2 0 Seven Residue Repeat Peptidase_M29 PF02073.15 KKK41906.1 - 1.9e-76 257.5 0.0 2.3e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) Peptidase_S51 PF03575.17 KKK41906.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Aminotran_1_2 PF00155.21 KKK41907.1 - 2.8e-63 214.3 0.0 3.2e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK41907.1 - 1.9e-06 27.1 0.0 7e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Alliinase_C PF04864.13 KKK41907.1 - 1.7e-05 23.9 0.0 6.3e-05 22.0 0.0 1.8 1 1 1 2 2 2 1 Allinase DegT_DnrJ_EryC1 PF01041.17 KKK41907.1 - 0.0025 17.2 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KKK41907.1 - 0.0038 15.8 0.0 0.0059 15.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK41907.1 - 0.065 12.5 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase PLDc_N PF13396.6 KKK41908.1 - 2.8e-05 23.9 3.1 2.8e-05 23.9 3.1 2.3 1 1 1 2 2 2 1 Phospholipase_D-nuclease N-terminal TssN PF17555.2 KKK41908.1 - 0.0024 17.3 3.0 0.0025 17.2 3.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssN DUF3413 PF11893.8 KKK41908.1 - 0.0026 17.0 3.5 0.0026 17.0 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3413) DUF4281 PF14108.6 KKK41908.1 - 0.012 16.0 4.3 0.021 15.2 4.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) DUF4064 PF13273.6 KKK41908.1 - 0.014 15.6 6.7 0.019 15.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) 7tm_3 PF00003.22 KKK41908.1 - 0.041 13.6 7.2 0.049 13.4 7.2 1.0 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF3792 PF12670.7 KKK41908.1 - 0.095 12.9 8.9 0.22 11.7 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) DUF4199 PF13858.6 KKK41908.1 - 0.27 11.6 5.4 0.32 11.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2207 PF09972.9 KKK41908.1 - 0.46 9.2 6.9 0.5 9.1 6.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) OATP PF03137.20 KKK41908.1 - 0.76 8.0 5.8 0.83 7.9 5.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_6 PF07332.11 KKK41908.1 - 1.6 8.8 14.7 0.077 13.0 7.5 1.9 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3810 PF12725.7 KKK41908.1 - 1.7 7.9 5.7 1.9 7.8 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) FixQ PF05545.11 KKK41908.1 - 2 8.5 13.7 3.3 7.7 3.7 2.5 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ CBP_BcsF PF11120.8 KKK41908.1 - 2.3 8.4 8.7 0.47 10.6 5.3 1.7 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsF Prominin PF05478.11 KKK41908.1 - 2.7 5.9 5.4 3 5.7 5.4 1.1 1 0 0 1 1 1 0 Prominin DUF3671 PF12420.8 KKK41908.1 - 2.7 8.1 6.0 4.1 7.5 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Mobilization_B PF17511.2 KKK41908.1 - 2.8 8.3 4.9 3.3 8.1 4.9 1.1 1 0 0 1 1 1 0 Mobilization protein B DUF4131 PF13567.6 KKK41908.1 - 2.8 7.6 8.3 3.4 7.3 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Hanta_G2 PF01561.16 KKK41908.1 - 3.3 6.2 7.6 0.12 11.0 1.6 1.5 2 0 0 2 2 2 0 Hantavirus glycoprotein G2 DUF2897 PF11446.8 KKK41908.1 - 3.7 7.5 12.4 2.4 8.1 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) DRTGG PF07085.12 KKK41910.1 - 2.6e-24 85.0 0.1 4.3e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 DRTGG domain AAA_26 PF13500.6 KKK41910.1 - 1.2e-21 77.5 0.0 1.8e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KKK41910.1 - 5.5e-05 23.2 0.0 0.00028 21.0 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Hpr_kinase_N PF02603.16 KKK41910.1 - 0.0015 18.6 0.0 0.0073 16.3 0.0 2.2 2 0 0 2 2 2 1 HPr Serine kinase N terminus ATP-grasp_5 PF13549.6 KKK41911.1 - 3.7e-68 229.3 0.0 5.2e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KKK41911.1 - 2e-52 176.6 0.2 8.7e-52 174.6 0.1 2.1 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK41911.1 - 3.5e-21 75.9 0.0 8.3e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK41911.1 - 2.2e-14 53.9 1.1 8.3e-14 52.1 0.5 2.4 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 KKK41911.1 - 0.0092 15.6 0.1 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Pro_isomerase PF00160.21 KKK41912.1 - 1.5e-39 135.8 0.7 1.6e-39 135.7 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HEAT_2 PF13646.6 KKK41913.1 - 2.3e-12 47.1 0.3 1e-11 45.0 0.1 2.3 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KKK41913.1 - 2.6e-09 36.6 0.0 0.02 15.1 0.0 3.5 3 0 0 3 3 3 3 HEAT repeat UPF0242 PF06785.11 KKK41913.1 - 0.018 15.2 14.4 0.018 15.2 14.4 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus RICTOR_M PF14666.6 KKK41913.1 - 0.35 10.7 3.6 0.9 9.3 0.4 2.7 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Spc7 PF08317.11 KKK41913.1 - 0.67 8.8 39.8 0.14 11.0 4.4 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Lectin_N PF03954.14 KKK41913.1 - 1.8 8.3 9.8 3.1 7.5 2.3 2.9 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Uso1_p115_C PF04871.13 KKK41913.1 - 3.1 8.2 28.3 2 8.8 20.0 2.7 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Csm1_N PF18504.1 KKK41913.1 - 9.2 6.7 32.3 3.7 8.0 3.4 5.6 4 1 1 5 5 5 0 Csm1 N-terminal domain Endonuclease_5 PF04493.14 KKK41914.1 - 1e-50 172.2 0.0 1.2e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V Cas_Cas5d PF09704.10 KKK41914.1 - 0.046 13.6 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) CbiA PF01656.23 KKK41915.1 - 8.2e-19 67.9 0.0 1.5e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKK41915.1 - 1.5e-10 41.3 0.6 3e-10 40.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 KKK41915.1 - 1.1e-09 38.1 0.9 4e-06 26.5 0.2 2.6 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 KKK41915.1 - 5.8e-08 32.3 0.4 2e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KKK41915.1 - 6.4e-07 29.1 0.7 0.0006 19.3 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KKK41915.1 - 8.2e-07 28.7 0.1 0.0039 16.7 0.1 2.1 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ AAA_30 PF13604.6 KKK41915.1 - 0.0026 17.5 0.0 0.0042 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKK41915.1 - 0.0052 16.5 0.1 0.27 11.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK41915.1 - 0.0068 16.8 0.0 0.009 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KKK41915.1 - 0.033 14.1 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 KKK41915.1 - 0.11 13.0 0.3 0.23 11.9 0.1 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KKK41915.1 - 0.12 12.0 1.2 0.16 11.6 0.5 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KKK41915.1 - 0.14 12.7 0.1 0.33 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKK41915.1 - 0.15 11.8 0.1 0.35 10.6 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 KKK41915.1 - 0.43 10.6 3.0 1.2 9.2 0.6 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain HupF_HypC PF01455.18 KKK41916.1 - 4.8e-24 84.3 0.3 5.6e-24 84.1 0.3 1.1 1 0 0 1 1 1 1 HupF/HypC family KTSC PF13619.6 KKK41916.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 KTSC domain TMEM238 PF15125.6 KKK41917.1 - 0.15 12.3 0.3 0.15 12.3 0.3 3.2 3 0 0 3 3 3 0 TMEM238 protein family RE_MjaI PF09568.10 KKK41918.1 - 0.28 11.0 2.8 1.3 8.8 0.2 2.8 2 1 1 3 3 3 0 MjaI restriction endonuclease CCG PF02754.16 KKK41919.1 - 1.6e-26 92.4 5.0 3.9e-15 55.8 0.7 2.2 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_16 PF13484.6 KKK41920.1 - 4.1e-11 43.7 4.8 7.2e-11 42.9 4.8 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK41920.1 - 2e-10 41.0 5.3 4.6e-10 39.8 5.4 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK41920.1 - 1.1e-08 35.5 5.0 2.1e-08 34.6 5.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK41920.1 - 2.5e-07 30.7 6.9 6.4e-07 29.4 7.1 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK41920.1 - 2e-06 28.2 7.8 3e-05 24.5 9.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41920.1 - 2.7e-05 24.2 11.8 0.00043 20.3 11.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK41920.1 - 0.0018 18.3 11.2 0.07 13.3 1.3 2.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK41920.1 - 0.0024 18.1 5.4 0.037 14.2 0.7 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK41920.1 - 0.0068 16.2 15.1 0.099 12.5 2.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK41920.1 - 0.18 12.0 14.5 0.22 11.7 2.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK41920.1 - 0.79 10.4 12.1 0.4 11.3 1.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK41920.1 - 2.6 9.2 16.0 5.5 8.2 4.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK41920.1 - 7.6 7.4 11.6 17 6.4 1.7 2.3 1 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK41920.1 - 8.6 7.0 11.4 6.1 7.5 2.2 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I NiFeSe_Hases PF00374.19 KKK41921.1 - 0.012 14.5 0.0 0.012 14.5 0.0 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Complex1_49kDa PF00346.19 KKK41921.1 - 0.019 14.1 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit ATP-synt_ab_N PF02874.23 KKK41926.1 - 2.4e-09 37.6 0.5 3.9e-09 36.9 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 KKK41926.1 - 0.00034 20.7 0.5 0.00053 20.1 0.5 1.5 1 1 0 1 1 1 1 HAS barrel domain ATP-synt_ab PF00006.25 KKK41926.1 - 0.0036 17.0 0.1 0.0062 16.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF4809 PF16067.5 KKK41926.1 - 0.068 13.3 0.5 0.11 12.7 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4809) ATP-synt_ab PF00006.25 KKK41927.1 - 3e-87 291.8 0.0 3.9e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KKK41927.1 - 7.4e-38 129.1 0.0 1.3e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KKK41927.1 - 2e-06 28.2 0.0 4.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain vATP-synt_E PF01991.18 KKK41928.1 - 0.00053 19.5 5.3 0.0009 18.7 5.3 1.6 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Mis12 PF05859.12 KKK41928.1 - 0.087 12.9 1.5 0.13 12.4 1.5 1.7 1 1 0 1 1 1 0 Mis12 protein Tape_meas_lam_C PF09718.10 KKK41928.1 - 0.16 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF1599 PF07659.11 KKK41928.1 - 4.7 7.7 9.7 0.2 12.1 0.7 3.0 3 1 0 3 3 3 0 Nucleotide modification associated domain 1 ATP-synt_F PF01990.17 KKK41929.1 - 2.4e-08 34.2 0.2 2.8e-08 34.0 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Apolipoprotein PF01442.18 KKK41930.1 - 0.0078 16.1 1.4 0.01 15.7 1.4 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Tup_N PF08581.10 KKK41930.1 - 0.026 14.8 4.4 0.037 14.3 3.2 2.0 1 1 1 2 2 2 0 Tup N-terminal Mt_ATP-synt_B PF05405.14 KKK41930.1 - 0.034 13.8 6.6 0.26 10.9 0.9 2.0 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ApoLp-III PF07464.11 KKK41930.1 - 0.055 13.6 3.7 0.069 13.2 3.0 1.4 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) V-ATPase_G PF03179.15 KKK41930.1 - 0.08 13.5 3.3 0.15 12.6 3.3 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Muted PF14942.6 KKK41930.1 - 0.098 13.0 6.4 0.11 12.8 6.4 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein HEPN_Toprim_N PF18871.1 KKK41930.1 - 0.11 12.4 1.5 0.14 12.0 1.5 1.1 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Mt_ATP-synt_D PF05873.12 KKK41930.1 - 0.14 12.0 4.8 0.43 10.4 4.8 1.7 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) SASA PF03629.18 KKK41930.1 - 0.18 11.4 0.5 0.89 9.2 0.2 1.9 1 1 1 2 2 2 0 Carbohydrate esterase, sialic acid-specific acetylesterase HSCB_C PF07743.13 KKK41930.1 - 0.22 12.0 6.3 4.3 7.9 1.2 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF883 PF05957.13 KKK41930.1 - 0.25 12.0 1.4 12 6.6 0.1 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SRI PF08236.11 KKK41930.1 - 0.26 11.5 4.4 1.7 8.9 0.4 2.1 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DUF5446 PF17522.2 KKK41930.1 - 0.58 10.4 7.8 0.27 11.4 2.0 2.3 1 1 2 3 3 3 0 Family of unknown function (DUF5446) RNase_J_C PF17770.1 KKK41930.1 - 1.4 10.0 5.2 14 6.9 0.5 2.3 1 1 0 2 2 2 0 Ribonuclease J C-terminal domain YtxH PF12732.7 KKK41930.1 - 1.8 9.1 6.7 72 4.0 6.7 2.3 1 1 0 1 1 1 0 YtxH-like protein vATP-synt_AC39 PF01992.16 KKK41931.1 - 1.2e-24 87.4 18.6 1.6e-24 87.1 18.6 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit RBB1NT PF08169.11 KKK41931.1 - 0.14 12.4 0.1 0.44 10.7 0.1 1.9 1 0 0 1 1 1 0 RBB1NT (NUC162) domain ATP-synt_C PF00137.21 KKK41932.1 - 3.5e-09 36.9 1.8 3.8e-09 36.7 1.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit C Mrx7 PF10906.8 KKK41935.1 - 0.063 13.5 0.2 1 9.6 0.0 2.5 2 0 0 2 2 2 0 MIOREX complex component 7 DUF3579 PF12112.8 KKK41935.1 - 0.14 12.7 0.2 1 10.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3579) DDE_Tnp_ISL3 PF01610.17 KKK41937.1 - 3.7e-13 49.7 0.8 2.1e-05 24.4 1.2 2.2 1 1 1 2 2 2 2 Transposase MULE PF10551.9 KKK41937.1 - 0.0055 17.1 0.0 0.018 15.5 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain Zn-ribbon_8 PF09723.10 KKK41938.1 - 0.00057 19.9 1.5 0.24 11.5 0.1 2.4 2 0 0 2 2 2 2 Zinc ribbon domain HypA PF01155.19 KKK41938.1 - 0.00062 19.8 0.5 1.2 9.2 0.1 2.4 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KKK41938.1 - 0.0018 18.6 0.1 0.0036 17.7 0.1 1.5 1 0 0 1 1 1 1 Restriction alleviation protein Lar CxC5 PF18718.1 KKK41938.1 - 0.0048 17.0 0.4 0.0072 16.4 0.4 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases Zn_Tnp_IS1595 PF12760.7 KKK41938.1 - 0.022 14.7 0.5 0.064 13.2 0.5 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.6 KKK41938.1 - 0.025 15.2 0.2 0.069 13.8 0.2 1.8 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.11 KKK41938.1 - 0.032 14.1 1.9 1.4 8.9 1.9 2.2 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2_3 PF13878.6 KKK41938.1 - 0.034 14.0 0.5 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Ribosomal_L37ae PF01780.19 KKK41938.1 - 0.034 14.2 1.1 0.27 11.4 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L37ae protein family TF_Zn_Ribbon PF08271.12 KKK41938.1 - 0.039 13.5 2.2 5.2 6.7 0.3 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding CxC3 PF18804.1 KKK41938.1 - 0.04 13.8 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases TFIIS_C PF01096.18 KKK41938.1 - 0.044 13.7 2.7 2.9 7.8 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF3427 PF11907.8 KKK41938.1 - 0.061 12.6 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) TackOD1 PF18551.1 KKK41938.1 - 0.063 12.9 0.9 0.15 11.7 0.9 1.6 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 Elf1 PF05129.13 KKK41938.1 - 0.088 12.9 0.9 0.28 11.3 0.9 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 KKK41938.1 - 0.11 12.0 3.5 2.1 7.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 KKK41938.1 - 0.17 11.8 2.0 3.1 7.7 0.1 2.6 2 1 1 3 3 3 0 Domain found in IF2B/IF5 zf-HYPF PF07503.12 KKK41938.1 - 0.2 11.5 4.1 5 7.0 0.2 2.3 2 0 0 2 2 2 0 HypF finger DZR PF12773.7 KKK41938.1 - 0.2 11.7 2.4 2.3 8.3 2.5 2.1 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK41938.1 - 0.25 11.1 4.6 3 7.7 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 KKK41938.1 - 1.8 8.7 5.6 22 5.3 5.5 2.5 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Rubredoxin_2 PF18073.1 KKK41938.1 - 2.2 8.1 6.2 6 6.7 0.5 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_4 PF13717.6 KKK41938.1 - 6.5 6.8 6.7 3.2 7.8 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin PF00301.20 KKK41938.1 - 9.3 6.4 7.0 2.9 8.0 0.7 2.6 3 0 0 3 3 2 0 Rubredoxin HTH_24 PF13412.6 KKK41939.1 - 0.0025 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF4364 PF14277.6 KKK41940.1 - 3.2e-05 23.7 0.0 3.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_45 PF14947.6 KKK41940.1 - 0.00044 20.2 0.0 0.00074 19.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_27 PF13463.6 KKK41940.1 - 0.01 16.3 0.1 0.017 15.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain DDE_Tnp_1_7 PF13843.6 KKK41942.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Transposase IS4 Glyco_hydro_57 PF03065.15 KKK41945.1 - 8.1e-38 130.4 0.0 1.3e-37 129.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF1957 PF09210.11 KKK41945.1 - 1e-24 86.8 0.2 1.9e-24 86.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1957) Penicillinase_R PF03965.16 KKK41945.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Penicillinase repressor PGM_PMM_I PF02878.16 KKK41946.1 - 8.3e-21 74.2 0.0 2.7e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KKK41946.1 - 1.8e-15 57.4 0.0 3.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKK41946.1 - 0.0044 17.2 0.0 0.0086 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CtsR_C PF17727.1 KKK41946.1 - 0.074 13.2 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain Rad51 PF08423.11 KKK41948.1 - 3.6e-91 305.0 0.1 4.2e-91 304.7 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KKK41948.1 - 1.8e-12 47.3 0.1 2.8e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KKK41948.1 - 3.6e-07 29.8 0.4 6.3e-07 29.0 0.4 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KKK41948.1 - 1.4e-06 28.8 0.3 5.8e-06 26.8 0.3 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 KKK41948.1 - 5.4e-06 26.1 0.0 1.4e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain IMS_HHH PF11798.8 KKK41948.1 - 0.0043 17.3 0.3 0.12 12.7 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif Cdd1 PF11731.8 KKK41948.1 - 0.035 14.4 0.1 0.44 10.8 0.0 2.5 2 1 1 3 3 3 0 Pathogenicity locus HHH PF00633.23 KKK41948.1 - 0.11 12.4 0.2 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif OsmC PF02566.19 KKK41949.1 - 3.1e-13 50.0 0.0 4.2e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein YdjM PF04307.14 KKK41950.1 - 4.5e-05 22.8 2.5 4.5e-05 22.8 2.5 1.6 1 1 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase SPW PF03779.14 KKK41950.1 - 0.019 14.5 0.7 0.045 13.4 0.1 1.9 2 0 0 2 2 2 0 SPW repeat FA_desaturase PF00487.24 KKK41950.1 - 9.3 6.0 10.4 3.7 7.3 2.0 2.1 1 1 1 2 2 2 0 Fatty acid desaturase PfkB PF00294.24 KKK41951.1 - 1.7e-17 63.7 0.0 1.5e-16 60.6 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Cnn_1N PF07989.11 KKK41952.1 - 9.9e-06 25.6 9.0 9.9e-06 25.6 9.0 6.2 4 1 0 4 4 3 1 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 KKK41952.1 - 0.0023 18.0 52.2 9.9 6.2 21.7 4.2 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Mto2_bdg PF12808.7 KKK41952.1 - 0.039 14.3 1.1 0.039 14.3 1.1 5.6 5 0 0 5 5 5 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ATG16 PF08614.11 KKK41952.1 - 0.072 13.3 47.3 0.11 12.7 22.4 4.5 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 KKK41952.1 - 0.21 12.1 0.2 0.21 12.1 0.2 5.8 4 1 2 6 6 6 0 Centrosome microtubule-binding domain of Cep57 kleA_kleC PF17383.2 KKK41952.1 - 0.83 10.0 7.0 3.6 8.0 0.1 4.3 2 1 1 4 4 4 0 Uncharacterized KorC regulated protein A Cep57_CLD_2 PF14197.6 KKK41952.1 - 2.4 8.3 0.0 2.4 8.3 0.0 6.7 7 2 0 7 7 7 0 Centrosome localisation domain of PPC89 DUF4806 PF16064.5 KKK41952.1 - 3.1 8.2 11.6 7.1 7.0 0.6 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4806) Spc7 PF08317.11 KKK41952.1 - 5.1 5.9 50.1 1.7 7.5 17.0 3.8 2 2 1 3 3 3 0 Spc7 kinetochore protein Atg14 PF10186.9 KKK41952.1 - 5.3 6.0 40.4 0.033 13.3 16.3 3.5 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 HOOK PF05622.12 KKK41952.1 - 8.1 4.5 49.2 0.12 10.5 24.8 2.2 1 1 0 2 2 2 0 HOOK protein KASH_CCD PF14662.6 KKK41952.1 - 9.8 6.0 54.7 34 4.2 0.2 4.8 2 2 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Memo PF01875.17 KKK41953.1 - 1.6e-53 181.6 0.0 1.8e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.18 KKK41953.1 - 5.5e-06 25.6 0.1 4.2e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase tRNA_int_endo PF01974.17 KKK41954.1 - 7e-28 96.5 0.1 1.4e-27 95.5 0.0 1.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KKK41954.1 - 2.3e-06 27.2 0.1 4.5e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain EF-hand_1 PF00036.32 KKK41954.1 - 0.15 11.6 0.2 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 EF hand B12-binding PF02310.19 KKK41955.1 - 4.1e-19 68.8 0.3 7.9e-19 67.9 0.1 1.6 2 0 0 2 2 2 1 B12 binding domain B12-binding_2 PF02607.17 KKK41955.1 - 0.0031 17.9 0.1 0.013 16.0 0.0 2.0 2 0 0 2 2 2 1 B12 binding domain Fe_dep_repress PF01325.19 KKK41955.1 - 0.082 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain CRS1_YhbY PF01985.21 KKK41955.1 - 0.14 12.3 1.1 0.37 11.0 0.1 2.1 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain DUF2284 PF10050.9 KKK41956.1 - 5.1e-32 110.9 0.3 8.4e-32 110.2 0.3 1.4 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) BRE1 PF08647.11 KKK41957.1 - 0.26 11.4 2.2 7.1 6.8 0.1 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase TusA PF01206.17 KKK41960.1 - 1.7e-18 66.2 0.0 1.9e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DrsE_2 PF13686.6 KKK41961.1 - 3.2e-25 88.8 1.2 1.3e-23 83.6 1.2 2.0 1 1 0 1 1 1 1 DsrE/DsrF/DrsH-like family DrsE PF02635.15 KKK41961.1 - 2.6e-06 27.8 0.0 5.8e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 DsrE/DsrF-like family HEAT_2 PF13646.6 KKK41962.1 - 8.4e-06 26.1 0.0 3.7e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 HEAT repeats Adaptin_N PF01602.20 KKK41962.1 - 1.3e-05 24.0 1.8 2e-05 23.4 0.6 1.7 1 1 1 2 2 2 1 Adaptin N terminal region CHASE4 PF05228.13 KKK41962.1 - 0.068 13.4 0.2 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 CHASE4 domain BHD_1 PF10403.9 KKK41965.1 - 0.05 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 Myb_DNA-bind_3 PF12776.7 KKK41966.1 - 0.11 13.5 2.1 1.1 10.3 0.1 3.1 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain HEAT_2 PF13646.6 KKK41967.1 - 5.8e-08 33.0 0.0 7.1e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KKK41967.1 - 0.0013 18.8 0.1 0.0034 17.5 0.1 1.6 1 0 0 1 1 1 1 HEAT repeat HEAT_EZ PF13513.6 KKK41967.1 - 0.0075 16.8 0.0 0.017 15.6 0.0 1.5 2 0 0 2 2 2 1 HEAT-like repeat TetR_N PF00440.23 KKK41970.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family zf-Di19 PF05605.12 KKK41970.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ThiC_Rad_SAM PF01964.18 KKK41971.1 - 4.2e-179 595.7 0.1 4.7e-179 595.5 0.1 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ADH_zinc_N PF00107.26 KKK41971.1 - 0.047 13.7 0.6 0.24 11.4 0.6 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Phos_pyr_kin PF08543.12 KKK41972.1 - 1.6e-97 325.7 2.7 1.8e-97 325.5 2.7 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KKK41972.1 - 1.1e-14 54.4 0.1 1.6e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 KKK41972.1 - 0.0019 17.7 1.4 0.0024 17.3 1.4 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family zf-RING_2 PF13639.6 KKK41973.1 - 2.4e-07 31.0 7.7 3.5e-07 30.4 7.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KKK41973.1 - 9.3e-05 22.6 9.1 0.00018 21.7 9.1 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KKK41973.1 - 0.00025 20.8 7.4 0.00039 20.2 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KKK41973.1 - 0.0058 16.5 4.4 0.0089 15.9 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK41973.1 - 0.0076 15.8 6.2 0.011 15.3 6.2 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type TPR_11 PF13414.6 KKK41973.1 - 0.0086 15.7 0.0 0.089 12.5 0.0 2.4 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.17 KKK41973.1 - 0.017 15.2 0.5 5.8 7.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-TFIIIC PF12660.7 KKK41973.1 - 0.019 14.9 2.7 0.03 14.3 2.7 1.5 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-C3HC4 PF00097.25 KKK41973.1 - 0.025 14.5 7.9 0.045 13.6 7.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_6 PF13174.6 KKK41973.1 - 0.026 15.2 0.4 0.87 10.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-P11 PF03854.14 KKK41973.1 - 0.089 12.5 6.0 0.15 11.7 6.0 1.4 1 0 0 1 1 1 0 P-11 zinc finger FANCL_C PF11793.8 KKK41973.1 - 0.12 12.5 10.1 2.4 8.4 10.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain TPR_1 PF00515.28 KKK41973.1 - 0.15 11.9 1.1 17 5.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RINGv PF12906.7 KKK41973.1 - 0.2 11.8 8.5 0.34 11.1 8.5 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_5 PF14634.6 KKK41973.1 - 0.21 11.6 6.2 0.33 11.0 6.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 KKK41973.1 - 0.4 10.8 2.7 0.67 10.0 2.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KKK41973.1 - 0.46 10.3 4.1 0.91 9.4 4.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KKK41973.1 - 0.75 9.7 6.6 1.5 8.7 6.6 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Ras PF00071.22 KKK41974.1 - 3.4e-42 143.8 5.0 1.4e-41 141.8 0.2 2.9 3 0 0 3 3 3 1 Ras family Roc PF08477.13 KKK41974.1 - 1.6e-28 99.4 0.3 1e-26 93.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41974.1 - 1.5e-16 60.3 1.2 8e-15 54.7 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK41974.1 - 8e-05 22.1 0.4 0.00016 21.2 0.4 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK41974.1 - 0.0015 18.1 0.1 0.046 13.3 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK41974.1 - 0.0072 16.4 0.0 0.043 13.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase TniB PF05621.11 KKK41974.1 - 0.055 12.9 0.2 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 KKK41974.1 - 0.92 9.5 3.9 2.3 8.3 0.1 3.1 2 2 0 2 2 2 0 AAA domain Ras PF00071.22 KKK41975.1 - 9.4e-43 145.6 2.6 1e-42 145.5 0.9 1.9 3 0 0 3 3 3 1 Ras family Roc PF08477.13 KKK41975.1 - 1.9e-25 89.4 0.0 6.3e-25 87.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK41975.1 - 2.9e-16 59.4 0.1 2.7e-15 56.3 0.0 2.1 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK41975.1 - 0.0066 15.8 0.7 0.0066 15.8 0.7 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region TniB PF05621.11 KKK41975.1 - 0.014 14.8 0.0 0.28 10.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 KKK41975.1 - 0.017 15.2 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK41975.1 - 0.093 12.3 0.1 0.83 9.2 0.0 2.2 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK41975.1 - 0.14 12.1 0.1 5.8 6.8 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Iso_dh PF00180.20 KKK41976.1 - 2.5e-102 342.6 0.0 2.8e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase 4HB_MCP_1 PF12729.7 KKK41977.1 - 0.83 9.2 2.4 1.4 8.4 2.4 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Acetyltransf_1 PF00583.25 KKK41978.1 - 1.3e-09 38.3 0.0 2.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK41978.1 - 4.4e-08 33.1 0.0 2e-06 27.7 0.0 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK41978.1 - 1.5e-07 31.7 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KKK41978.1 - 0.0015 18.1 0.3 0.0021 17.6 0.3 1.5 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 KKK41978.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 KKK41978.1 - 0.011 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 KKK41978.1 - 0.025 14.7 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KKK41978.1 - 0.051 13.2 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_4 PF13420.7 KKK41978.1 - 0.053 13.6 0.1 0.1 12.8 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CBFD_NFYB_HMF PF00808.23 KKK41979.1 - 1.2e-08 35.2 0.0 1.3e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2299 PF10061.9 KKK41985.1 - 1.6e-17 63.5 0.0 2.5e-17 62.9 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) DUF211 PF02680.14 KKK41986.1 - 7e-25 87.0 0.6 8.4e-25 86.8 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized ArCR, COG1888 PKI PF02827.16 KKK41986.1 - 0.11 12.7 0.3 0.67 10.2 0.1 2.0 1 1 1 2 2 2 0 cAMP-dependent protein kinase inhibitor UPF0184 PF03670.13 KKK41986.1 - 0.17 12.3 1.3 1.3 9.4 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF1877 PF08974.10 KKK41988.1 - 4.6e-32 111.4 0.1 5.1e-32 111.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) HAD_2 PF13419.6 KKK41989.1 - 5.7e-29 101.4 3.4 8.1e-29 101.0 3.4 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK41989.1 - 3.1e-16 60.3 0.2 2.1e-14 54.3 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK41989.1 - 4.3e-12 45.9 0.0 7.2e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 KKK41989.1 - 1.4e-05 25.0 9.5 0.0013 18.5 6.8 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase NIF PF03031.18 KKK41989.1 - 0.018 14.8 0.5 0.31 10.8 0.5 2.4 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase HTH_26 PF13443.6 KKK41989.1 - 0.059 13.8 0.1 0.61 10.6 0.0 2.5 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Acid_phosphat_B PF03767.14 KKK41989.1 - 0.089 12.4 2.8 1.8 8.1 0.5 2.7 1 1 1 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) NCD1 PF04904.13 KKK41989.1 - 0.15 12.1 0.0 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) LigT_PEase PF02834.16 KKK41990.1 - 4e-16 59.0 0.0 2.2e-07 31.0 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 KKK41990.1 - 2.9e-14 53.5 2.6 4e-14 53.0 2.6 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KKK41990.1 - 2.6e-08 33.9 0.0 3.2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.12 KKK41990.1 - 0.0035 16.7 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Coronavirus NS2A protein 2-Hacid_dh_C PF02826.19 KKK41991.1 - 1e-39 135.8 0.0 1.5e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK41991.1 - 1.2e-10 41.2 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK41991.1 - 2e-08 34.6 0.0 5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase zf-FCS PF06467.14 KKK41992.1 - 1.2e-05 25.1 1.5 1.5e-05 24.8 1.5 1.2 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif zf-FLZ PF04570.14 KKK41992.1 - 0.01 15.3 1.2 0.3 10.6 0.1 2.0 2 0 0 2 2 2 2 zinc-finger of the FCS-type, C2-C2 DUF2175 PF09943.9 KKK41992.1 - 0.035 14.4 0.9 0.037 14.3 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Sulfatase PF00884.23 KKK41994.1 - 3.8e-39 134.9 0.0 7.7e-39 133.9 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK41994.1 - 4.5e-10 39.6 0.0 1.4e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK41994.1 - 0.0021 16.8 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) MFA1_2 PF17317.2 KKK41994.1 - 0.018 14.8 1.1 0.045 13.5 1.1 1.6 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 DUF2555 PF10742.9 KKK41994.1 - 0.026 14.3 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Metalloenzyme PF01676.18 KKK41994.1 - 0.028 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Glyco_hydro_2_C PF02836.17 KKK41995.1 - 3.5e-105 351.4 1.2 3.5e-105 351.4 1.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KKK41995.1 - 1.9e-68 230.7 0.1 3.2e-68 230.0 0.1 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KKK41995.1 - 5.5e-48 163.1 2.7 1.6e-47 161.5 2.7 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KKK41995.1 - 6.7e-22 77.8 0.0 1.4e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KKK41995.1 - 4e-15 56.4 0.0 1.1e-14 55.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KKK41995.1 - 0.052 14.1 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Picorna_P3A PF06363.11 KKK41995.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Picornaviridae P3A protein Fer4 PF00037.27 KKK41996.1 - 1.4e-07 31.0 14.4 1.5e-05 24.6 1.6 3.2 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK41996.1 - 3.6e-07 31.0 5.2 4.7e-05 24.2 0.4 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK41996.1 - 1.8e-05 24.8 11.6 1.8e-05 24.8 11.6 2.3 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK41996.1 - 6.4e-05 23.0 24.1 0.002 18.2 14.1 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK41996.1 - 8.2e-05 23.1 0.5 8.2e-05 23.1 0.5 2.8 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK41996.1 - 0.00022 21.1 1.9 0.00022 21.1 1.9 3.3 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK41996.1 - 0.00047 20.2 11.7 0.00047 20.2 11.7 2.5 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK41996.1 - 0.00077 19.4 3.2 0.00077 19.4 3.2 3.3 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 KKK41996.1 - 0.044 14.7 5.5 0.044 14.7 5.5 3.8 3 1 0 3 3 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK41996.1 - 0.052 14.1 5.7 0.052 14.1 5.7 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain HTH_20 PF12840.7 KKK41996.1 - 0.22 11.6 0.1 0.56 10.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Gtr1_RagA PF04670.12 KKK41997.1 - 1.4e-26 93.3 0.9 1.9e-26 92.8 0.9 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK41997.1 - 4.3e-17 62.1 0.1 6.9e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK41997.1 - 2.7e-05 23.7 0.3 4.8e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK41997.1 - 4.7e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK41997.1 - 0.0022 18.1 0.0 0.0047 17.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase APS_kinase PF01583.20 KKK41997.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 KKK41997.1 - 0.2 12.0 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KKK41997.1 - 3.1 8.2 7.7 11 6.4 7.7 2.1 1 1 0 1 1 1 0 AAA domain Creatininase PF02633.14 KKK41998.1 - 8.3e-61 205.5 0.0 9.3e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase COesterase PF00135.28 KKK41999.1 - 4.8e-115 385.3 0.0 6e-115 385.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK41999.1 - 3.3e-12 46.7 0.0 5.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK41999.1 - 9.7e-05 21.9 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KKK41999.1 - 0.055 12.3 0.0 9.2 5.0 0.0 2.9 3 0 0 3 3 3 0 Steryl acetyl hydrolase Spc7 PF08317.11 KKK42000.1 - 1.9e-07 30.3 41.5 3e-05 23.0 18.6 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Fib_alpha PF08702.10 KKK42000.1 - 2.2e-06 27.9 34.6 3.2e-06 27.4 11.1 2.4 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family HrpB7 PF09486.10 KKK42000.1 - 9.1e-06 26.1 12.2 0.0011 19.3 1.0 3.3 1 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB7) Pox_A_type_inc PF04508.12 KKK42000.1 - 9.1e-06 25.3 9.4 0.13 12.2 0.0 5.0 5 0 0 5 5 3 2 Viral A-type inclusion protein repeat SlyX PF04102.12 KKK42000.1 - 1.2e-05 25.8 27.4 0.018 15.6 1.3 4.7 1 1 4 5 5 5 3 SlyX UPF0242 PF06785.11 KKK42000.1 - 2.2e-05 24.7 38.7 0.00095 19.3 20.3 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus CALCOCO1 PF07888.11 KKK42000.1 - 2.2e-05 23.5 37.0 6.9e-05 21.9 26.3 2.3 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 KKK42000.1 - 2.3e-05 24.7 44.7 0.44 10.7 23.3 3.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Filament PF00038.21 KKK42000.1 - 2.9e-05 23.8 33.9 0.00058 19.5 8.9 3.0 1 1 2 3 3 3 1 Intermediate filament protein Fez1 PF06818.15 KKK42000.1 - 4.8e-05 23.9 34.4 0.18 12.3 5.7 3.2 1 1 2 3 3 3 3 Fez1 Lebercilin PF15619.6 KKK42000.1 - 9.7e-05 22.1 38.5 0.00057 19.6 20.5 2.7 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease CCDC144C PF14915.6 KKK42000.1 - 0.00017 20.8 34.7 0.00027 20.2 34.7 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region MAD PF05557.13 KKK42000.1 - 0.00029 19.4 37.0 0.0007 18.1 37.0 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein Bacillus_HBL PF05791.11 KKK42000.1 - 0.00032 20.6 10.8 0.00032 20.6 10.8 3.2 1 1 2 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 KKK42000.1 - 0.00036 20.6 43.7 0.026 14.6 10.6 3.4 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 KKK42000.1 - 0.00075 18.8 35.4 0.00075 18.8 35.4 2.2 1 1 1 2 2 2 1 HAP1 N-terminal conserved region FliJ PF02050.16 KKK42000.1 - 0.00094 19.4 22.3 0.12 12.6 7.7 3.1 1 1 2 3 3 3 2 Flagellar FliJ protein MscS_porin PF12795.7 KKK42000.1 - 0.0011 18.6 46.8 0.0033 17.0 29.8 2.3 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain ERM PF00769.19 KKK42000.1 - 0.0014 18.5 30.3 0.064 13.1 11.6 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family DUF4686 PF15742.5 KKK42000.1 - 0.0022 17.2 36.6 0.011 14.9 36.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4686) EzrA PF06160.12 KKK42000.1 - 0.0024 16.1 31.4 0.0048 15.1 31.4 1.5 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA HMMR_N PF15905.5 KKK42000.1 - 0.0025 17.3 41.5 0.081 12.4 31.3 2.2 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 KKK42000.1 - 0.0026 18.1 37.7 0.96 9.9 1.4 5.7 3 1 3 6 6 6 1 Flagella accessory protein C (FlaC) FPP PF05911.11 KKK42000.1 - 0.003 15.9 41.7 0.032 12.5 41.6 2.0 1 1 0 1 1 1 1 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 KKK42000.1 - 0.003 17.6 43.1 0.021 14.8 8.8 3.5 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.14 KKK42000.1 - 0.003 17.4 6.7 0.003 17.4 6.7 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF724) DUF4472 PF14739.6 KKK42000.1 - 0.0032 18.2 34.6 0.044 14.5 3.8 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4472) Myosin_tail_1 PF01576.19 KKK42000.1 - 0.0043 14.9 33.7 0.015 13.1 33.8 1.8 1 1 0 1 1 1 1 Myosin tail HOOK PF05622.12 KKK42000.1 - 0.0044 15.2 40.7 0.049 11.8 15.6 1.9 1 1 0 1 1 1 1 HOOK protein DUF3584 PF12128.8 KKK42000.1 - 0.0054 14.3 29.0 0.0074 13.9 29.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) COG2 PF06148.11 KKK42000.1 - 0.0056 16.8 2.7 0.0056 16.8 2.7 4.0 1 1 3 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin PF00261.20 KKK42000.1 - 0.0072 15.7 32.7 0.012 15.0 32.7 1.3 1 0 0 1 1 1 1 Tropomyosin HAUS-augmin3 PF14932.6 KKK42000.1 - 0.0097 15.5 38.2 0.042 13.4 19.7 2.2 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 HIP1_clath_bdg PF16515.5 KKK42000.1 - 0.011 16.4 42.3 0.14 12.7 6.4 3.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DHR10 PF18595.1 KKK42000.1 - 0.012 15.7 36.5 0.14 12.2 8.3 4.1 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain DUF3552 PF12072.8 KKK42000.1 - 0.014 14.8 35.3 0.11 11.9 8.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) Seryl_tRNA_N PF02403.22 KKK42000.1 - 0.015 15.5 34.5 0.035 14.3 8.4 3.9 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Golgin_A5 PF09787.9 KKK42000.1 - 0.015 14.8 38.8 0.37 10.2 38.9 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 KKK42000.1 - 0.017 14.3 31.5 0.22 10.6 14.8 2.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 KKK42000.1 - 0.019 13.6 32.4 0.054 12.2 10.8 2.0 1 1 1 2 2 2 0 AAA domain DUF4200 PF13863.6 KKK42000.1 - 0.023 15.1 28.7 0.75 10.2 13.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Tropomyosin_1 PF12718.7 KKK42000.1 - 0.023 14.8 43.4 0.62 10.2 8.8 3.2 1 1 1 3 3 3 0 Tropomyosin like KELK PF15796.5 KKK42000.1 - 0.025 15.0 28.8 0.026 15.0 6.9 3.7 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Syntaxin-6_N PF09177.11 KKK42000.1 - 0.026 15.1 8.5 0.026 15.1 8.5 3.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 KKK42000.1 - 0.029 13.7 28.6 0.045 13.1 13.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Sugarporin_N PF11471.8 KKK42000.1 - 0.037 14.0 0.9 0.037 14.0 0.9 3.3 5 0 0 5 5 1 0 Maltoporin periplasmic N-terminal extension TMF_DNA_bd PF12329.8 KKK42000.1 - 0.038 14.0 51.9 0.086 12.8 4.9 5.1 1 1 5 6 6 6 0 TATA element modulatory factor 1 DNA binding CEP63 PF17045.5 KKK42000.1 - 0.04 13.8 29.8 0.04 13.8 12.6 2.7 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa Leu_zip PF15294.6 KKK42000.1 - 0.04 13.4 37.7 0.023 14.2 19.5 2.3 1 1 1 2 2 2 0 Leucine zipper DUF1664 PF07889.12 KKK42000.1 - 0.043 13.9 27.3 0.048 13.7 8.0 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 KKK42000.1 - 0.045 13.6 6.8 9.1 6.2 0.2 5.1 4 2 2 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPR_MLP1_2 PF07926.12 KKK42000.1 - 0.053 13.6 43.9 0.063 13.3 8.8 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.9 KKK42000.1 - 0.054 12.5 36.6 0.39 9.6 5.6 2.9 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 GAS PF13851.6 KKK42000.1 - 0.054 12.8 38.2 0.54 9.6 28.1 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin PF02996.17 KKK42000.1 - 0.1 12.5 36.0 1 9.3 2.8 5.4 1 1 3 5 5 5 0 Prefoldin subunit PI_PP_I PF18363.1 KKK42000.1 - 0.1 12.8 14.2 0.74 10.0 5.4 2.8 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain Exonuc_VII_L PF02601.15 KKK42000.1 - 0.12 12.0 31.1 0.41 10.2 13.0 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF5082 PF16888.5 KKK42000.1 - 0.12 12.6 35.4 3.6 7.9 20.7 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) TMPIT PF07851.13 KKK42000.1 - 0.13 11.5 28.6 0.26 10.5 10.7 2.2 1 1 1 2 2 2 0 TMPIT-like protein Sec8_exocyst PF04048.14 KKK42000.1 - 0.14 12.1 33.1 0.34 10.8 11.3 3.7 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain DUF641 PF04859.12 KKK42000.1 - 0.14 12.5 28.9 1.1 9.6 7.8 3.7 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) zf-BED PF02892.15 KKK42000.1 - 0.15 12.1 0.7 1.7 8.8 0.3 2.5 2 0 0 2 2 2 0 BED zinc finger CC2-LZ PF16516.5 KKK42000.1 - 0.16 12.4 30.9 2 8.8 4.7 4.5 1 1 2 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Prefoldin_2 PF01920.20 KKK42000.1 - 0.17 11.8 40.5 0.16 11.9 13.3 5.1 1 1 2 4 4 4 0 Prefoldin subunit TF_Zn_Ribbon PF08271.12 KKK42000.1 - 0.22 11.1 0.8 17 5.0 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KKK42000.1 - 0.26 10.7 2.2 10 5.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Nsp1_C PF05064.13 KKK42000.1 - 0.28 11.0 30.7 1.9 8.3 7.3 3.4 1 1 2 3 3 3 0 Nsp1-like C-terminal region EspB_PE PF18625.1 KKK42000.1 - 0.31 11.5 11.8 2.5 8.6 0.4 3.9 3 1 1 4 4 3 0 ESX-1 secreted protein B PE domain TMF_TATA_bd PF12325.8 KKK42000.1 - 0.39 10.9 38.5 0.41 10.9 4.9 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Zn_Tnp_IS1595 PF12760.7 KKK42000.1 - 0.41 10.7 1.5 1 9.4 1.5 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF3450 PF11932.8 KKK42000.1 - 0.44 9.8 35.4 0.099 11.9 10.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) PRKG1_interact PF15898.5 KKK42000.1 - 0.66 10.9 39.0 3.3 8.7 10.9 3.4 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 KKK42000.1 - 0.69 9.7 41.9 5 6.9 13.8 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KKK42000.1 - 0.83 10.2 43.3 11 6.5 15.6 3.6 1 1 2 3 3 2 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 KKK42000.1 - 0.84 9.8 29.5 1.3 9.2 2.7 4.5 2 2 1 4 4 4 0 TolA binding protein trimerisation YkyA PF10368.9 KKK42000.1 - 0.88 9.2 36.7 0.19 11.4 14.8 2.8 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Cast PF10174.9 KKK42000.1 - 0.99 7.6 36.0 1.6 6.8 7.1 2.4 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone TACC_C PF05010.14 KKK42000.1 - 1 9.1 30.7 0.32 10.8 10.4 2.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Nudix_N_2 PF14803.6 KKK42000.1 - 1.1 9.2 3.1 17 5.4 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal WEMBL PF05701.11 KKK42000.1 - 1.2 7.7 35.2 3.6e+02 -0.4 24.2 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light YscO PF07321.12 KKK42000.1 - 1.3 8.9 22.5 0.044 13.8 4.2 3.1 1 1 2 3 3 3 0 Type III secretion protein YscO DUF4201 PF13870.6 KKK42000.1 - 1.4 8.7 33.7 1.2 8.9 11.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Sec2p PF06428.11 KKK42000.1 - 1.6 8.8 41.6 1.4 9.0 1.0 5.0 1 1 4 5 5 5 0 GDP/GTP exchange factor Sec2p APG17 PF04108.12 KKK42000.1 - 1.6 7.7 34.8 0.25 10.4 22.9 2.2 1 1 1 2 2 2 0 Autophagy protein Apg17 Cas_Cas4 PF01930.17 KKK42000.1 - 1.6 8.8 11.5 8.9 6.4 3.2 3.2 1 1 0 2 2 2 0 Domain of unknown function DUF83 Rab5-bind PF09311.11 KKK42000.1 - 2.2 7.6 32.8 0.28 10.6 8.1 2.7 1 1 1 2 2 2 0 Rabaptin-like protein OmpH PF03938.14 KKK42000.1 - 2.4 8.5 30.4 1.8e+04 -10.7 30.4 3.3 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) DUF4763 PF15960.5 KKK42000.1 - 3 7.1 29.8 47 3.2 21.4 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DivIVA PF05103.13 KKK42000.1 - 3.6 7.7 31.4 3 7.9 8.8 3.1 1 1 1 3 3 3 0 DivIVA protein SYCE1 PF15233.6 KKK42000.1 - 3.6 7.6 33.1 1.7 8.7 15.8 2.4 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 AATF-Che1 PF13339.6 KKK42000.1 - 3.7 8.2 31.9 0.76 10.4 10.2 2.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor AIP3 PF03915.13 KKK42000.1 - 3.9 6.5 30.5 13 4.7 30.5 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 DUF745 PF05335.13 KKK42000.1 - 4.4 7.0 33.6 0.079 12.7 5.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Cortex-I_coil PF09304.10 KKK42000.1 - 4.5 7.5 32.0 2.4 8.4 10.6 3.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil Med9 PF07544.13 KKK42000.1 - 4.6 7.4 24.3 0.9 9.7 1.6 4.2 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF2203 PF09969.9 KKK42000.1 - 4.7 8.0 20.3 4.9 7.9 4.8 3.5 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) DUF812 PF05667.11 KKK42000.1 - 4.7 6.0 38.1 2.2 7.1 13.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Cep57_CLD PF14073.6 KKK42000.1 - 5.9 6.9 33.5 5.3 7.0 23.2 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 CorA PF01544.18 KKK42000.1 - 6.7 5.9 19.1 4.2 6.6 7.2 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Nup54 PF13874.6 KKK42000.1 - 7.2 6.7 26.1 8.8e+02 -0.0 0.1 3.0 1 1 0 2 2 1 0 Nucleoporin complex subunit 54 Macoilin PF09726.9 KKK42000.1 - 7.4 5.0 31.6 18 3.7 31.7 1.5 1 1 0 1 1 1 0 Macoilin family Val_tRNA-synt_C PF10458.9 KKK42000.1 - 7.6 6.9 17.4 0.11 12.8 1.4 4.3 3 1 2 5 5 3 0 Valyl tRNA synthetase tRNA binding arm THOC7 PF05615.13 KKK42000.1 - 7.8 6.8 29.8 10 6.4 12.3 3.8 1 1 3 4 4 4 0 Tho complex subunit 7 ApoO PF09769.9 KKK42000.1 - 7.8 6.5 13.9 0.39 10.7 1.1 3.4 1 1 3 4 4 4 0 Apolipoprotein O DivIC PF04977.15 KKK42000.1 - 8.2 6.3 37.1 0.66 9.8 1.4 5.4 1 1 2 5 5 5 0 Septum formation initiator USP8_interact PF08941.10 KKK42000.1 - 8.6 6.1 20.2 7.2 6.4 1.0 3.9 1 1 3 4 4 4 0 USP8 interacting Laminin_II PF06009.12 KKK42000.1 - 8.8 6.3 36.4 3.2 7.8 9.4 3.7 1 1 3 4 4 4 0 Laminin Domain II Spc7 PF08317.11 KKK42001.1 - 1.2e-07 31.0 41.4 1.9e-05 23.8 18.6 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 KKK42001.1 - 2e-06 27.4 10.1 0.023 14.6 0.1 4.9 5 0 0 5 5 3 2 Viral A-type inclusion protein repeat Fib_alpha PF08702.10 KKK42001.1 - 2.5e-06 27.7 34.1 3.6e-06 27.2 10.7 2.4 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family CALCOCO1 PF07888.11 KKK42001.1 - 6.2e-06 25.4 37.1 0.00018 20.5 23.0 2.3 1 1 0 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 KKK42001.1 - 1.2e-05 25.8 26.3 0.026 15.1 1.0 4.7 1 1 4 5 5 5 3 SlyX UPF0242 PF06785.11 KKK42001.1 - 1.7e-05 25.0 38.6 0.0004 20.5 20.8 2.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 KKK42001.1 - 1.9e-05 25.0 44.0 0.085 13.1 12.6 3.5 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Filament PF00038.21 KKK42001.1 - 3.6e-05 23.5 33.4 0.00095 18.8 8.7 3.0 1 1 2 3 3 3 1 Intermediate filament protein Fez1 PF06818.15 KKK42001.1 - 4.6e-05 24.0 34.8 0.18 12.2 5.4 3.2 1 1 2 3 3 3 3 Fez1 HrpB7 PF09486.10 KKK42001.1 - 4.6e-05 23.8 12.0 0.0039 17.6 0.4 3.1 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB7) Lebercilin PF15619.6 KKK42001.1 - 0.00014 21.6 38.1 0.00088 19.0 20.2 2.8 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Bacillus_HBL PF05791.11 KKK42001.1 - 0.00019 21.3 10.6 0.00019 21.3 10.6 3.1 1 1 2 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) Exonuc_VII_L PF02601.15 KKK42001.1 - 0.00021 20.9 26.0 0.012 15.2 13.6 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit CCDC144C PF14915.6 KKK42001.1 - 0.00029 20.1 34.4 0.00046 19.4 34.4 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region MAD PF05557.13 KKK42001.1 - 0.00032 19.2 37.1 0.00071 18.1 37.1 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein MscS_porin PF12795.7 KKK42001.1 - 0.0004 20.0 23.9 0.0004 20.0 23.9 2.4 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain ADIP PF11559.8 KKK42001.1 - 0.00067 19.8 43.2 0.027 14.6 10.6 3.4 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding FliJ PF02050.16 KKK42001.1 - 0.00084 19.6 21.2 0.11 12.7 7.6 3.0 1 1 2 3 3 3 2 Flagellar FliJ protein DUF4686 PF15742.5 KKK42001.1 - 0.0015 17.8 35.8 0.021 14.0 35.8 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4686) Golgin_A5 PF09787.9 KKK42001.1 - 0.0018 17.8 24.6 0.0018 17.8 24.6 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 EzrA PF06160.12 KKK42001.1 - 0.0022 16.3 31.2 0.0043 15.3 31.2 1.5 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA FPP PF05911.11 KKK42001.1 - 0.0024 16.2 41.7 0.038 12.2 41.7 2.2 1 1 0 1 1 1 1 Filament-like plant protein, long coiled-coil HAP1_N PF04849.13 KKK42001.1 - 0.0027 17.0 39.2 0.0029 16.9 36.6 2.3 1 1 1 2 2 2 1 HAP1 N-terminal conserved region Myosin_tail_1 PF01576.19 KKK42001.1 - 0.0028 15.6 33.8 0.0072 14.2 33.8 1.7 1 1 0 1 1 1 1 Myosin tail Leu_zip PF15294.6 KKK42001.1 - 0.0028 17.2 14.6 0.0028 17.2 14.6 2.3 1 1 1 2 2 2 1 Leucine zipper HMMR_N PF15905.5 KKK42001.1 - 0.0029 17.1 41.3 0.091 12.2 30.8 2.2 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KKK42001.1 - 0.0029 17.6 43.2 0.023 14.7 8.6 3.5 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 KKK42001.1 - 0.0033 15.0 27.9 0.0045 14.6 27.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4472 PF14739.6 KKK42001.1 - 0.0034 18.1 35.0 0.045 14.5 3.7 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4472) DUF724 PF05266.14 KKK42001.1 - 0.0041 17.0 7.3 0.0041 17.0 7.3 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF724) FlaC_arch PF05377.11 KKK42001.1 - 0.0045 17.3 38.2 1.5 9.3 1.8 5.7 3 1 3 6 6 6 1 Flagella accessory protein C (FlaC) HOOK PF05622.12 KKK42001.1 - 0.0046 15.2 40.4 0.077 11.1 15.7 1.9 1 1 0 1 1 1 1 HOOK protein HAUS-augmin3 PF14932.6 KKK42001.1 - 0.0053 16.4 37.4 0.14 11.8 21.9 2.2 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 ERM PF00769.19 KKK42001.1 - 0.006 16.4 30.7 0.23 11.3 11.9 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Prefoldin PF02996.17 KKK42001.1 - 0.0061 16.5 32.3 1.2 9.1 2.4 5.4 2 1 3 5 5 5 2 Prefoldin subunit COG2 PF06148.11 KKK42001.1 - 0.0068 16.5 2.6 0.0068 16.5 2.6 4.0 1 1 3 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3552 PF12072.8 KKK42001.1 - 0.0079 15.6 35.2 0.064 12.7 7.9 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) HIP1_clath_bdg PF16515.5 KKK42001.1 - 0.0095 16.5 42.0 0.18 12.4 6.8 3.7 1 1 3 4 4 4 2 Clathrin-binding domain of Huntingtin-interacting protein 1 Tropomyosin PF00261.20 KKK42001.1 - 0.01 15.2 33.2 0.017 14.5 33.2 1.3 1 0 0 1 1 1 0 Tropomyosin Seryl_tRNA_N PF02403.22 KKK42001.1 - 0.014 15.6 34.5 0.024 14.9 7.5 3.9 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain KELK PF15796.5 KKK42001.1 - 0.017 15.5 28.5 0.027 14.9 7.0 3.7 1 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase AAA_13 PF13166.6 KKK42001.1 - 0.022 13.4 32.5 0.15 10.6 12.5 2.0 1 1 1 2 2 2 0 AAA domain CEP63 PF17045.5 KKK42001.1 - 0.023 14.6 29.5 0.033 14.1 12.1 2.6 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa YscO PF07321.12 KKK42001.1 - 0.025 14.5 4.0 0.025 14.5 4.0 3.1 1 1 2 3 3 3 0 Type III secretion protein YscO DUF4200 PF13863.6 KKK42001.1 - 0.028 14.8 28.8 0.89 10.0 13.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 KKK42001.1 - 0.029 14.4 52.0 0.071 13.1 5.1 5.2 1 1 5 6 6 6 0 TATA element modulatory factor 1 DNA binding Sugarporin_N PF11471.8 KKK42001.1 - 0.037 14.0 0.9 0.037 14.0 0.9 3.0 4 0 0 4 4 1 0 Maltoporin periplasmic N-terminal extension Tropomyosin_1 PF12718.7 KKK42001.1 - 0.043 14.0 43.9 0.78 9.9 8.9 3.2 1 1 1 3 3 3 0 Tropomyosin like DHR10 PF18595.1 KKK42001.1 - 0.045 13.8 36.7 0.39 10.8 15.1 4.1 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 KKK42001.1 - 0.046 13.1 28.6 0.071 12.5 12.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KKK42001.1 - 0.048 12.7 31.3 2 7.4 18.5 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 KKK42001.1 - 0.054 12.5 36.1 0.43 9.5 5.3 2.9 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 PKcGMP_CC PF16808.5 KKK42001.1 - 0.06 13.2 7.5 9.1 6.2 0.2 5.2 4 2 2 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 KKK42001.1 - 0.063 13.3 27.0 0.069 13.2 7.6 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KKK42001.1 - 0.065 13.3 43.9 0.11 12.6 8.2 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KKK42001.1 - 0.069 12.5 38.8 0.49 9.7 27.0 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 KKK42001.1 - 0.1 11.8 28.2 0.21 10.8 10.4 2.2 1 1 1 2 2 2 0 TMPIT-like protein DUF5082 PF16888.5 KKK42001.1 - 0.12 12.7 35.1 3 8.1 20.8 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) PI_PP_I PF18363.1 KKK42001.1 - 0.16 12.2 13.8 0.74 10.0 5.4 2.8 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain Sec8_exocyst PF04048.14 KKK42001.1 - 0.16 11.8 33.3 1.4 8.8 14.6 3.7 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain CC2-LZ PF16516.5 KKK42001.1 - 0.17 12.3 30.9 2.2 8.7 4.9 4.5 1 1 2 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Prefoldin_2 PF01920.20 KKK42001.1 - 0.18 11.8 40.2 0.25 11.3 13.1 5.3 1 1 2 4 4 4 0 Prefoldin subunit DUF641 PF04859.12 KKK42001.1 - 0.21 11.9 28.8 0.99 9.7 7.4 3.7 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) TF_Zn_Ribbon PF08271.12 KKK42001.1 - 0.22 11.1 0.9 15 5.2 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Nsp1_C PF05064.13 KKK42001.1 - 0.28 11.0 30.5 1.7 8.5 7.0 3.4 1 1 2 3 3 3 0 Nsp1-like C-terminal region zf-ribbon_3 PF13248.6 KKK42001.1 - 0.3 10.6 2.1 13 5.4 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain EspB_PE PF18625.1 KKK42001.1 - 0.42 11.1 11.8 3.4 8.2 0.4 3.9 3 1 1 4 4 3 0 ESX-1 secreted protein B PE domain TolA_bind_tri PF16331.5 KKK42001.1 - 0.5 10.5 28.7 0.71 10.0 1.9 4.4 2 2 1 4 4 4 0 TolA binding protein trimerisation DUF3450 PF11932.8 KKK42001.1 - 0.52 9.6 34.8 0.12 11.7 9.5 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Zn_Tnp_IS1595 PF12760.7 KKK42001.1 - 0.53 10.3 1.9 1.4 9.0 1.9 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 KKK42001.1 - 0.63 10.0 3.0 11 6.1 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal YkyA PF10368.9 KKK42001.1 - 0.67 9.6 37.0 0.19 11.4 14.8 2.8 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein PRKG1_interact PF15898.5 KKK42001.1 - 0.69 10.8 38.8 3.5 8.6 10.8 3.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 KKK42001.1 - 0.9 9.8 38.3 1.1 9.5 5.0 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Cast PF10174.9 KKK42001.1 - 0.95 7.6 36.3 1.5 7.0 7.1 2.4 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone TACC_C PF05010.14 KKK42001.1 - 0.98 9.2 30.5 0.32 10.8 10.4 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4201 PF13870.6 KKK42001.1 - 1.3 8.7 34.3 0.92 9.2 10.9 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 KKK42001.1 - 1.4 8.7 42.2 7.7 6.3 23.1 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Syntaxin-6_N PF09177.11 KKK42001.1 - 1.4 9.5 33.2 0.054 14.1 8.7 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF745 PF05335.13 KKK42001.1 - 1.5 8.5 33.1 0.26 11.0 11.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Rab5-bind PF09311.11 KKK42001.1 - 1.6 8.1 32.0 0.19 11.1 7.4 2.7 1 1 1 2 2 2 0 Rabaptin-like protein APG6_N PF17675.1 KKK42001.1 - 1.6 9.3 43.7 7.7 7.1 14.9 3.5 1 1 2 3 3 2 0 Apg6 coiled-coil region Sec2p PF06428.11 KKK42001.1 - 1.6 8.7 42.3 1.3 9.1 0.8 5.0 1 1 4 5 5 5 0 GDP/GTP exchange factor Sec2p WEMBL PF05701.11 KKK42001.1 - 1.7 7.2 34.7 0.088 11.5 4.3 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Cas_Cas4 PF01930.17 KKK42001.1 - 1.7 8.7 11.8 5.9 7.0 0.2 3.2 1 1 2 3 3 3 0 Domain of unknown function DUF83 APG17 PF04108.12 KKK42001.1 - 2.1 7.4 34.7 0.32 10.1 22.7 2.2 1 1 1 2 2 2 0 Autophagy protein Apg17 DivIVA PF05103.13 KKK42001.1 - 2.2 8.3 31.1 2.4 8.2 8.5 3.1 1 1 2 3 3 3 0 DivIVA protein DUF4763 PF15960.5 KKK42001.1 - 2.5 7.3 29.3 6.2e+03 -3.8 29.3 3.0 1 1 0 1 1 0 0 Domain of unknown function (DUF4763) AATF-Che1 PF13339.6 KKK42001.1 - 2.6 8.7 31.4 0.69 10.6 10.0 2.6 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor AIP3 PF03915.13 KKK42001.1 - 3 6.8 29.8 9.5 5.2 29.8 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 DUF2203 PF09969.9 KKK42001.1 - 3.9 8.2 19.9 4.6 8.0 4.7 3.4 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) Cortex-I_coil PF09304.10 KKK42001.1 - 4.7 7.5 32.0 1.6 8.9 10.0 3.5 1 1 2 3 3 3 0 Cortexillin I, coiled coil THOC7 PF05615.13 KKK42001.1 - 5.3 7.3 28.7 13 6.1 12.9 4.0 1 1 3 4 4 4 0 Tho complex subunit 7 DUF812 PF05667.11 KKK42001.1 - 5.3 5.8 38.0 5.4 5.8 16.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) SYCE1 PF15233.6 KKK42001.1 - 5.7 7.0 33.2 1.3 9.1 15.3 2.4 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Med9 PF07544.13 KKK42001.1 - 6.1 7.0 23.9 56 3.9 8.1 4.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.12 KKK42001.1 - 6.8 6.7 36.4 3 7.8 3.1 3.7 1 1 3 4 4 4 0 Laminin Domain II Val_tRNA-synt_C PF10458.9 KKK42001.1 - 7.4 6.9 17.6 0.1 12.9 1.6 4.3 3 1 2 5 5 3 0 Valyl tRNA synthetase tRNA binding arm DivIC PF04977.15 KKK42001.1 - 7.7 6.4 36.7 0.65 9.8 1.3 5.4 1 1 4 5 5 5 0 Septum formation initiator Cep57_CLD PF14073.6 KKK42001.1 - 7.8 6.5 33.5 4.3 7.3 23.0 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 ApoO PF09769.9 KKK42001.1 - 8.7 6.3 13.3 0.64 10.0 0.4 3.4 1 1 3 4 4 4 0 Apolipoprotein O Macoilin PF09726.9 KKK42001.1 - 9 4.7 31.6 19 3.6 31.7 1.4 1 1 0 1 1 1 0 Macoilin family Nup54 PF13874.6 KKK42001.1 - 9.8 6.3 25.2 1.7 8.7 7.2 3.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Hexapep_2 PF14602.6 KKK42002.1 - 1.6e-07 31.0 0.1 1.6e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KKK42002.1 - 0.00012 21.6 1.7 0.00092 18.9 0.1 2.5 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) DUF3955 PF13127.6 KKK42002.1 - 0.26 11.1 6.6 0.1 12.4 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) Hexapep PF00132.24 KKK42003.1 - 4.1e-08 32.6 4.0 0.002 17.8 0.0 3.0 2 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK42003.1 - 7.5e-07 28.8 4.4 0.0025 17.6 0.0 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Metallophos PF00149.28 KKK42004.1 - 7.4e-22 78.8 2.9 2e-16 61.1 1.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK42004.1 - 1.1e-14 54.9 0.0 5.3e-10 39.7 0.1 2.7 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Virulence_RhuM PF13310.6 KKK42004.1 - 0.096 11.9 0.4 0.57 9.4 0.2 2.1 2 0 0 2 2 2 0 Virulence protein RhuM family ThiS PF02597.20 KKK42005.1 - 0.00081 20.0 0.0 0.001 19.7 0.0 1.2 1 0 0 1 1 1 1 ThiS family Urm1 PF09138.11 KKK42005.1 - 0.02 15.2 0.2 0.023 15.1 0.2 1.2 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Gtr1_RagA PF04670.12 KKK42006.1 - 1.3e-18 67.3 0.7 1.9e-18 66.7 0.7 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK42006.1 - 5e-06 26.1 0.0 8.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_S25 PF03297.15 KKK42007.1 - 2.1e-07 31.1 4.3 2.3e-07 30.9 4.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_28 PF13518.6 KKK42007.1 - 0.088 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.10 KKK42007.1 - 0.092 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator Methyltransf_11 PF08241.12 KKK42008.1 - 2.5e-09 37.6 0.0 4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK42008.1 - 2.8e-07 31.2 0.0 4.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK42008.1 - 9.8e-05 22.2 0.0 0.00016 21.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK42008.1 - 0.006 17.3 0.0 0.04 14.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK42008.1 - 0.018 14.8 0.1 0.88 9.3 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 KKK42008.1 - 0.054 12.9 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 KKK42008.1 - 0.098 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CarboxypepD_reg PF13620.6 KKK42009.1 - 2.4e-05 24.5 0.3 6.7e-05 23.1 0.3 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 KKK42009.1 - 0.0021 18.3 0.6 0.0067 16.7 0.1 2.1 2 0 0 2 2 2 1 Prealbumin-like fold domain Big_1 PF02369.16 KKK42009.1 - 0.0026 17.7 0.4 0.0072 16.3 0.4 1.8 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) bMG3 PF11974.8 KKK42009.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain DUF3937 PF13073.6 KKK42009.1 - 0.34 11.0 1.6 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) Aminotran_1_2 PF00155.21 KKK42012.1 - 3.6e-54 184.3 0.0 4e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KKK42012.1 - 0.00011 21.3 0.0 0.00014 20.8 0.0 1.1 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.19 KKK42012.1 - 0.0002 20.5 0.1 0.0028 16.6 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KKK42012.1 - 0.016 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KKK42012.1 - 0.09 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KKK42012.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.7 1 1 1 2 2 2 0 Beta-eliminating lyase PLDc_N PF13396.6 KKK42013.1 - 0.00016 21.5 5.3 0.00016 21.5 5.3 2.4 1 1 1 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF4281 PF14108.6 KKK42013.1 - 0.0016 18.8 3.1 0.0025 18.2 3.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4281) DUF3681 PF12442.8 KKK42013.1 - 0.0033 17.9 1.7 0.0037 17.7 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3681) DUF4064 PF13273.6 KKK42013.1 - 0.0039 17.5 8.6 0.0051 17.1 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) 7tm_3 PF00003.22 KKK42013.1 - 0.0098 15.6 7.3 0.012 15.4 7.3 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4282 PF14110.6 KKK42013.1 - 0.06 14.1 10.1 0.074 13.8 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF3413 PF11893.8 KKK42013.1 - 0.065 12.4 3.6 0.064 12.4 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) TssN PF17555.2 KKK42013.1 - 0.089 12.2 5.7 0.093 12.1 5.7 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN YrhC PF14143.6 KKK42013.1 - 0.13 12.3 2.8 0.18 11.9 2.8 1.2 1 0 0 1 1 1 0 YrhC-like protein PKD_channel PF08016.12 KKK42013.1 - 0.18 10.4 5.9 0.19 10.4 5.9 1.0 1 0 0 1 1 1 0 Polycystin cation channel DUF2784 PF10861.8 KKK42013.1 - 0.18 11.8 7.6 0.21 11.7 7.6 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) XK-related PF09815.9 KKK42013.1 - 0.22 10.6 6.9 0.24 10.4 6.9 1.0 1 0 0 1 1 1 0 XK-related protein DUF4199 PF13858.6 KKK42013.1 - 0.33 11.3 8.8 0.38 11.1 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Saf_2TM PF18303.1 KKK42013.1 - 0.51 9.9 5.5 0.23 11.0 3.6 1.4 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4131 PF13567.6 KKK42013.1 - 0.54 9.9 5.8 0.65 9.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Tmemb_55A PF09788.9 KKK42013.1 - 0.66 9.0 4.9 0.67 9.0 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein 55A Phage_holin_3_6 PF07332.11 KKK42013.1 - 0.84 9.7 11.7 0.056 13.5 5.5 1.8 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3290 PF11694.8 KKK42013.1 - 1 9.3 6.3 1.2 9.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) OATP PF03137.20 KKK42013.1 - 1.2 7.3 7.0 1.3 7.2 7.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2530 PF10745.9 KKK42013.1 - 1.4 9.2 5.8 1.7 8.9 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) E1-E2_ATPase PF00122.20 KKK42013.1 - 2.2 7.7 4.9 2.5 7.6 4.9 1.1 1 0 0 1 1 1 0 E1-E2 ATPase DUF2207 PF09972.9 KKK42013.1 - 2.8 6.6 8.4 3.1 6.4 8.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3810 PF12725.7 KKK42013.1 - 3.3 7.0 6.8 3.5 6.9 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3671 PF12420.8 KKK42013.1 - 3.5 7.7 8.8 5.6 7.1 8.8 1.4 1 1 0 1 1 1 0 Protein of unknown function PemK_toxin PF02452.17 KKK42018.1 - 6e-20 71.7 0.1 6.7e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system HTH_34 PF13601.6 KKK42020.1 - 4.1e-09 36.5 0.0 6.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4423 PF14394.6 KKK42020.1 - 0.0034 17.1 0.0 0.0043 16.8 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4423) B-block_TFIIIC PF04182.12 KKK42020.1 - 0.0037 17.4 0.8 0.012 15.8 0.2 1.9 1 1 1 2 2 2 1 B-block binding subunit of TFIIIC HTH_Mga PF08280.11 KKK42020.1 - 0.006 16.6 0.4 0.011 15.7 0.4 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Cullin PF00888.22 KKK42020.1 - 0.0064 15.2 0.1 0.0064 15.2 0.1 1.2 1 0 0 1 1 1 1 Cullin family PadR PF03551.14 KKK42020.1 - 0.0078 16.2 0.0 0.024 14.6 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family RPA_C PF08784.11 KKK42020.1 - 0.084 13.5 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal DUF87 PF01935.17 KKK42022.1 - 2.4e-07 31.1 0.1 4.4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KKK42022.1 - 1e-06 28.3 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF853 PF05872.12 KKK42022.1 - 8.9e-05 21.3 0.0 0.00014 20.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_7 PF12775.7 KKK42022.1 - 9.8e-05 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KKK42022.1 - 0.00016 21.9 0.0 0.00065 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKK42022.1 - 0.00019 20.6 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Pox_A32 PF04665.12 KKK42022.1 - 0.0012 18.4 0.9 0.0026 17.3 0.9 1.6 1 0 0 1 1 1 1 Poxvirus A32 protein TrwB_AAD_bind PF10412.9 KKK42022.1 - 0.0012 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ATPase PF06745.13 KKK42022.1 - 0.0029 17.0 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_10 PF12846.7 KKK42022.1 - 0.0039 16.2 0.1 0.85 8.5 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain ResIII PF04851.15 KKK42022.1 - 0.042 13.9 0.5 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KKK42022.1 - 0.056 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_32 PF13654.6 KKK42022.1 - 0.067 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK42022.1 - 0.09 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC2_membrane_2 PF12679.7 KKK42022.1 - 0.11 11.8 2.5 0.15 11.3 2.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_33 PF13671.6 KKK42022.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KKK42022.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3810 PF12725.7 KKK42022.1 - 0.34 10.2 3.5 0.57 9.5 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Wzy_C PF04932.15 KKK42022.1 - 3.6 7.2 5.4 5.8 6.5 5.4 1.5 1 1 0 1 1 1 0 O-Antigen ligase Cucumopine_C PF18631.1 KKK42023.1 - 0.084 12.8 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain Rnk_N PF14760.6 KKK42023.1 - 0.094 13.2 0.2 0.16 12.5 0.2 1.4 1 0 0 1 1 1 0 Rnk N-terminus Tetraspanin PF00335.20 KKK42024.1 - 6.7 6.4 15.3 9 5.9 7.4 2.2 2 0 0 2 2 2 0 Tetraspanin family URO-D PF01208.17 KKK42025.1 - 1e-10 41.3 0.0 1.3e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PorB PF11565.8 KKK42025.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha helical Porin B NotI PF12183.8 KKK42025.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NotI tRNA-synt_1c PF00749.21 KKK42030.1 - 3e-44 151.2 0.1 4.2e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKK42030.1 - 3.4e-22 79.2 0.0 6.2e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DNA_RNApol_7kD PF03604.13 KKK42031.1 - 0.00021 20.9 0.6 0.0004 20.0 0.6 1.5 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit FAST_1 PF06743.15 KKK42031.1 - 0.038 14.0 0.8 0.2 11.6 0.2 2.6 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 HypA PF01155.19 KKK42031.1 - 0.12 12.4 0.1 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sec20 PF03908.13 KKK42031.1 - 0.12 12.3 1.9 0.43 10.5 0.1 2.9 2 1 1 3 3 3 0 Sec20 zinc_ribbon_2 PF13240.6 KKK42031.1 - 0.4 10.5 4.4 2.7 7.8 4.4 2.1 1 1 0 1 1 1 0 zinc-ribbon domain 7TMR-HDED PF07697.11 KKK42031.1 - 0.45 10.6 3.3 0.65 10.1 0.5 2.5 2 1 0 2 2 2 0 7TM-HD extracellular zf-ribbon_3 PF13248.6 KKK42031.1 - 3.7 7.1 5.5 21 4.7 5.6 1.9 1 1 0 1 1 1 0 zinc-ribbon domain CPBP PF02517.16 KKK42032.1 - 1.9e-13 50.6 7.0 1.9e-13 50.6 7.0 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DZR PF12773.7 KKK42032.1 - 0.00034 20.6 0.1 0.00054 19.9 0.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK42032.1 - 0.00034 20.2 2.3 0.00064 19.4 2.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK42032.1 - 0.0026 17.1 1.7 0.012 15.0 0.1 2.1 2 0 0 2 2 2 1 zinc-ribbon domain Nudix_N_2 PF14803.6 KKK42032.1 - 0.42 10.6 1.5 20 5.2 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal Cys_rich_KTR PF14205.6 KKK42032.1 - 0.44 10.4 4.2 1.4 8.8 4.2 1.9 1 1 0 1 1 1 0 Cysteine-rich KTR RNA_POL_M_15KD PF02150.16 KKK42032.1 - 1 9.3 5.1 5.5 6.9 0.2 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit PTA_PTB PF01515.19 KKK42033.1 - 0.0012 18.3 0.0 0.0032 16.8 0.0 1.8 1 1 0 1 1 1 1 Phosphate acetyl/butaryl transferase DUF4231 PF14015.6 KKK42034.1 - 0.78 10.2 6.0 0.1 13.1 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF1033 PF06279.11 KKK42035.1 - 0.11 12.7 1.4 1.9 8.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) DUF4600 PF15372.6 KKK42035.1 - 0.79 10.2 6.3 0.15 12.5 1.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4600) DUF1896 PF08989.10 KKK42036.1 - 0.14 12.2 3.6 0.19 11.8 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1896) DUF5063 PF16702.5 KKK42036.1 - 0.3 11.5 2.3 0.5 10.7 0.8 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5063) DUF4147 PF13660.6 KKK42040.1 - 4.8e-72 242.2 0.0 7.2e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 KKK42040.1 - 2.2e-25 89.0 0.1 3.9e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 MOFRL family Pyr_redox_2 PF07992.14 KKK42041.1 - 2.8e-60 204.0 3.8 1e-58 198.9 0.9 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK42041.1 - 3.5e-27 94.8 0.9 1.3e-26 93.0 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKK42041.1 - 4.4e-23 81.6 2.9 3.4e-18 66.0 0.0 4.0 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK42041.1 - 7.3e-16 58.2 1.2 5.1e-12 45.6 0.3 3.3 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK42041.1 - 1.1e-12 47.8 2.1 3.8e-07 29.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK42041.1 - 6.1e-08 32.4 0.0 9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK42041.1 - 3.3e-07 29.4 8.3 1.5e-05 23.9 0.5 3.9 4 1 1 5 5 5 2 HI0933-like protein NAD_binding_8 PF13450.6 KKK42041.1 - 4.7e-07 29.9 0.9 0.00018 21.7 0.4 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 KKK42041.1 - 1e-06 28.3 0.5 0.0013 18.1 0.0 3.5 4 0 0 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KKK42041.1 - 2.7e-06 26.7 9.1 2.6e-05 23.5 0.7 4.2 4 1 1 5 5 5 1 FAD binding domain 3HCDH_N PF02737.18 KKK42041.1 - 2.9e-06 27.3 1.9 0.0011 18.8 0.0 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KKK42041.1 - 4.1e-06 26.3 1.4 0.022 14.0 0.1 3.2 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.24 KKK42041.1 - 7.4e-06 25.8 10.4 0.018 14.6 0.8 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK42041.1 - 1.4e-05 24.5 1.2 0.091 12.0 0.0 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KKK42041.1 - 0.0012 18.1 0.0 0.014 14.6 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KKK42041.1 - 0.0014 19.0 0.2 1.2 9.6 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KKK42041.1 - 0.0043 16.2 0.5 0.59 9.1 0.3 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DUF1847 PF08901.11 KKK42041.1 - 0.0044 16.7 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1847) Thi4 PF01946.17 KKK42041.1 - 0.0056 16.0 0.2 0.034 13.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family PTS_IIB PF02302.17 KKK42041.1 - 0.0065 17.1 0.5 0.11 13.2 0.0 3.1 3 0 0 3 3 3 1 PTS system, Lactose/Cellobiose specific IIB subunit ThiF PF00899.21 KKK42041.1 - 0.0074 15.7 0.2 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 ThiF family UDPG_MGDP_dh_N PF03721.14 KKK42041.1 - 0.04 13.5 0.9 1.4 8.5 0.0 2.7 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 KKK42041.1 - 0.18 10.6 0.5 0.36 9.6 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KKK42041.1 - 8.2 6.4 6.2 4.1 7.4 0.2 3.0 4 0 0 4 4 3 0 FAD-NAD(P)-binding Metallophos PF00149.28 KKK42042.1 - 1.8e-10 41.7 0.0 5.4e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_28 PF02636.17 KKK42042.1 - 0.017 14.7 0.0 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3216 PF11505.8 KKK42042.1 - 0.17 12.1 2.5 2.4 8.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) LSM PF01423.22 KKK42043.1 - 6.9e-16 57.7 0.7 8.1e-16 57.5 0.7 1.1 1 0 0 1 1 1 1 LSM domain eRF1_3 PF03465.15 KKK42044.1 - 0.00071 20.0 0.0 0.0019 18.7 0.0 1.8 1 1 0 1 1 1 1 eRF1 domain 3 Pox_E2-like PF04497.12 KKK42044.1 - 0.00081 18.0 0.1 0.0012 17.4 0.1 1.2 1 0 0 1 1 1 1 Poxviridae protein PAS_4 PF08448.10 KKK42045.1 - 1.6e-18 67.0 0.0 6.1e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKK42045.1 - 2.6e-18 66.2 2.7 8.9e-15 54.8 0.1 3.2 3 1 0 3 3 3 2 PAS domain HATPase_c PF02518.26 KKK42045.1 - 6.9e-15 55.5 0.4 1.6e-14 54.3 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 KKK42045.1 - 1.5e-14 53.9 0.1 2.9e-11 43.4 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 KKK42045.1 - 1e-12 47.8 0.0 1e-08 35.0 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KKK42045.1 - 7.4e-05 23.0 0.0 0.0067 16.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 KKK42045.1 - 0.005 16.8 0.4 0.011 15.7 0.4 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Roc PF08477.13 KKK42045.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase HisKA_4TM PF16926.5 KKK42045.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase Acetyltransf_3 PF13302.7 KKK42046.1 - 5.7e-25 88.6 0.0 7.4e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK42046.1 - 6.1e-09 36.1 0.0 8.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KKK42046.1 - 6.7e-09 36.1 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKK42046.1 - 1.9e-08 34.1 0.0 9.3e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_31 PF13847.6 KKK42047.1 - 2.2e-18 66.5 0.2 2.7e-18 66.2 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK42047.1 - 3.2e-17 63.0 0.0 4.5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK42047.1 - 6.6e-15 55.6 0.0 9.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK42047.1 - 4.9e-14 52.2 0.0 6.5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK42047.1 - 4.5e-11 43.4 0.0 7.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK42047.1 - 2.6e-10 40.4 0.0 2.9e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK42047.1 - 1.4e-08 34.5 0.1 1.7e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KKK42047.1 - 7.8e-08 32.0 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 KKK42047.1 - 9.6e-06 25.6 0.1 5.7e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.19 KKK42047.1 - 2.1e-05 24.7 0.0 2.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 KKK42047.1 - 2.4e-05 24.2 0.0 3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.17 KKK42047.1 - 3.7e-05 23.3 0.1 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KKK42047.1 - 3.9e-05 23.1 0.0 4.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KKK42047.1 - 8.5e-05 22.2 0.1 0.00013 21.6 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KKK42047.1 - 0.0001 22.1 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KKK42047.1 - 0.00016 21.7 0.1 0.00057 19.8 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Fibrillarin PF01269.17 KKK42047.1 - 0.00053 19.2 0.0 0.00064 18.9 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin Methyltr_RsmB-F PF01189.17 KKK42047.1 - 0.00063 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_2 PF00891.18 KKK42047.1 - 0.0017 17.7 0.1 0.0022 17.3 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain GCD14 PF08704.10 KKK42047.1 - 0.0022 17.7 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.6 KKK42047.1 - 0.0023 18.9 0.0 0.0031 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KKK42047.1 - 0.0028 16.3 0.0 0.0033 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DRE2_N PF16803.5 KKK42047.1 - 0.04 14.2 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Inhibitor_I66 PF16850.5 KKK42048.1 - 0.055 13.3 0.1 0.06 13.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase inhibitor I66 ACD PF16671.5 KKK42048.1 - 0.093 11.0 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Actin cross-linking domain EF-hand_14 PF17959.1 KKK42049.1 - 0.0011 19.3 0.0 5.4 7.4 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain adh_short PF00106.25 KKK42050.1 - 1.4e-44 151.9 0.0 2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK42050.1 - 4.7e-28 98.3 0.0 5.8e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK42050.1 - 2.3e-08 34.2 0.0 2.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKK42050.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK42050.1 - 0.00026 20.5 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KKK42050.1 - 0.00041 20.3 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KKK42050.1 - 0.00042 19.6 0.1 0.00067 18.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KKK42050.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KKK42050.1 - 0.025 14.7 0.1 0.057 13.5 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1955 PF09205.10 KKK42050.1 - 0.036 13.8 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) NAD_Gly3P_dh_N PF01210.23 KKK42050.1 - 0.036 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RmlD_sub_bind PF04321.17 KKK42050.1 - 0.046 12.8 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF3212 PF11486.8 KKK42050.1 - 0.053 13.5 0.1 0.25 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3212) 2-Hacid_dh_C PF02826.19 KKK42050.1 - 0.11 11.9 0.0 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KKK42050.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 KKK42050.1 - 0.17 11.6 0.0 0.54 9.9 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF401 PF04165.12 KKK42051.1 - 4.1e-23 82.3 19.3 5e-23 82.1 19.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF401) NTP_transf_3 PF12804.7 KKK42055.1 - 3.5e-10 40.5 0.0 3.9e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KKK42055.1 - 0.009 15.6 0.0 0.0097 15.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase CMD PF02627.20 KKK42058.1 - 4.2e-09 36.3 0.0 5.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Sigma70_r4 PF04545.16 KKK42058.1 - 0.089 12.3 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF2182 PF09948.9 KKK42058.1 - 0.21 11.4 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) DZR PF12773.7 KKK42059.1 - 8.1e-12 45.0 20.0 2.8e-08 33.6 12.1 2.5 2 1 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK42059.1 - 9.4e-09 34.4 20.4 7.5e-05 22.0 3.9 4.2 4 0 0 4 4 4 3 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK42059.1 - 6.4e-08 32.1 27.7 0.011 15.4 2.9 3.9 3 1 0 3 3 3 3 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK42059.1 - 0.0029 18.3 18.2 0.14 12.9 4.8 2.9 1 1 1 2 2 2 2 zinc-ribbon family TackOD1 PF18551.1 KKK42059.1 - 0.0039 16.9 12.8 0.016 14.9 12.8 1.9 1 1 0 1 1 1 1 Thaumarchaeal output domain 1 DUF2207 PF09972.9 KKK42059.1 - 0.02 13.7 0.4 0.021 13.6 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zinc-ribbons_6 PF07191.12 KKK42059.1 - 0.065 13.2 16.5 3.9 7.5 9.6 2.9 1 1 1 2 2 2 0 zinc-ribbons TMEM208_SND2 PF05620.11 KKK42059.1 - 0.1 12.3 3.2 0.14 11.9 3.2 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Nudix_N_2 PF14803.6 KKK42059.1 - 0.14 12.1 18.7 3.6 7.6 0.2 5.6 5 1 1 6 6 6 0 Nudix N-terminal NinF PF05810.12 KKK42059.1 - 0.17 11.8 0.4 0.17 11.8 0.4 3.0 2 1 0 2 2 2 0 NinF protein zf-RRN7 PF11781.8 KKK42059.1 - 0.22 11.2 15.2 35 4.2 0.3 5.1 4 1 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf_UBZ PF18439.1 KKK42059.1 - 0.48 10.1 25.4 2.1 8.0 0.3 6.2 4 2 3 7 7 7 0 Ubiquitin-Binding Zinc Finger PHF5 PF03660.14 KKK42059.1 - 0.73 10.1 13.4 0.61 10.3 6.4 2.1 1 1 0 2 2 2 0 PHF5-like protein zinc-ribbon_6 PF10005.9 KKK42059.1 - 1.1 10.0 12.0 3.3 8.5 0.3 3.1 2 2 1 3 3 3 0 zinc-ribbon domain FYVE_2 PF02318.16 KKK42059.1 - 1.6 9.0 10.8 0.89 9.8 4.2 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger UPF0547 PF10571.9 KKK42059.1 - 1.6 8.9 19.5 5 7.3 4.7 4.3 3 1 2 5 5 5 0 Uncharacterised protein family UPF0547 DUF2321 PF10083.9 KKK42059.1 - 2.5 7.7 16.4 30 4.2 0.2 3.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C3HC4_3 PF13920.6 KKK42059.1 - 4.8 7.1 22.5 0.75 9.7 0.2 4.2 2 2 2 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C2HC5 PF06221.13 KKK42059.1 - 5 7.2 17.8 1.7 8.7 0.7 3.8 2 1 2 4 4 4 0 Putative zinc finger motif, C2HC5-type Prok-RING_1 PF14446.6 KKK42059.1 - 9.7 6.2 20.5 0.78 9.7 0.7 3.3 2 1 2 4 4 4 0 Prokaryotic RING finger family 1 zf-ribbon_3 PF13248.6 KKK42060.1 - 0.00072 18.9 0.6 0.49 9.9 0.0 2.2 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 KKK42060.1 - 0.00077 19.4 0.5 0.00094 19.2 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon Prok-RING_1 PF14446.6 KKK42060.1 - 0.00086 19.2 2.6 0.0012 18.8 2.6 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 KKK42060.1 - 0.0022 17.8 0.4 0.0029 17.4 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 KKK42060.1 - 0.023 14.7 0.6 0.024 14.7 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ins_beta PF03488.14 KKK42060.1 - 0.027 14.5 1.8 0.04 13.9 1.8 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type DUF3039 PF11238.8 KKK42060.1 - 0.029 14.1 0.6 0.036 13.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-C2HC5 PF06221.13 KKK42060.1 - 0.032 14.2 0.4 0.044 13.8 0.4 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-UDP PF14569.6 KKK42060.1 - 0.053 13.6 3.8 0.2 11.8 3.8 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger Cas_CXXC_CXXC PF09706.10 KKK42060.1 - 0.42 10.9 5.4 3.2 8.1 0.3 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zinc_ribbon_2 PF13240.6 KKK42060.1 - 0.83 9.5 5.4 6.7 6.6 5.4 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Ribosomal_S30 PF04758.14 KKK42061.1 - 2.6e-12 46.7 1.5 2.6e-12 46.7 1.5 1.6 1 1 1 2 2 2 1 Ribosomal protein S30 TPR_2 PF07719.17 KKK42062.1 - 6.5e-09 35.2 0.5 0.013 15.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK42062.1 - 8.9e-06 25.9 0.1 0.062 13.6 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK42062.1 - 2.3e-05 24.0 2.3 0.014 15.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK42062.1 - 0.00013 21.5 0.0 0.2 11.0 0.0 2.4 1 1 2 3 3 3 3 MalT-like TPR region SNAP PF14938.6 KKK42062.1 - 0.00045 19.7 0.8 0.00085 18.8 0.8 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 KKK42062.1 - 0.001 18.8 6.4 0.0032 17.2 0.9 2.4 2 0 0 2 2 2 1 26S proteasome subunit RPN7 DUF410 PF04190.13 KKK42062.1 - 0.0053 16.6 0.8 0.015 15.1 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF410) TPR_6 PF13174.6 KKK42062.1 - 0.015 15.9 0.0 10 7.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK42062.1 - 0.52 10.7 5.0 84 3.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zinc_ribbon_2 PF13240.6 KKK42063.1 - 2.6e-05 23.8 2.7 4.7e-05 23.0 2.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK42063.1 - 0.00042 19.6 1.4 0.00066 19.0 1.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain RNase_E_G PF10150.9 KKK42063.1 - 0.001 18.6 1.8 0.0013 18.2 1.4 1.4 1 1 0 1 1 1 1 Ribonuclease E/G family DZR PF12773.7 KKK42063.1 - 0.003 17.5 3.0 0.0048 16.9 3.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-RanBP PF00641.18 KKK42063.1 - 0.65 9.4 3.7 1.3 8.4 3.7 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others MoCF_biosynth PF00994.24 KKK42065.1 - 4e-27 94.7 0.0 4.7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain B12-binding PF02310.19 KKK42065.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain EamA PF00892.20 KKK42072.1 - 1.3e-06 28.6 4.3 1.4e-05 25.3 4.3 1.9 1 1 0 1 1 1 1 EamA-like transporter family AhpC-TSA PF00578.21 KKK42075.1 - 1.1e-08 35.1 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK42075.1 - 1e-07 31.8 0.0 1.3e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF2140 PF09911.9 KKK42075.1 - 0.088 12.4 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Guanylate_kin PF00625.21 KKK42077.1 - 2.1e-13 50.4 0.0 2.7e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase CoaE PF01121.20 KKK42077.1 - 0.0011 18.7 0.9 0.0013 18.4 0.1 1.5 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_33 PF13671.6 KKK42077.1 - 0.0014 18.8 0.7 0.02 15.1 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK42077.1 - 0.0086 16.6 1.7 0.034 14.7 1.7 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KKK42077.1 - 0.048 13.8 0.1 0.066 13.3 0.1 1.2 1 0 0 1 1 1 0 Shikimate kinase ABC_tran PF00005.27 KKK42077.1 - 0.075 13.6 0.0 0.17 12.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KKK42077.1 - 0.084 12.6 0.3 0.14 11.9 0.3 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 KKK42077.1 - 0.14 12.6 2.1 0.73 10.3 0.2 2.4 2 1 0 2 2 2 0 AAA domain Fe_dep_repress PF01325.19 KKK42078.1 - 3.5e-13 49.5 0.0 5.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 KKK42078.1 - 1.8e-12 47.1 1.1 2.8e-12 46.6 1.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HTH_Crp_2 PF13545.6 KKK42078.1 - 6.7e-08 32.4 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 KKK42078.1 - 4.7e-07 29.6 0.0 9.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KKK42078.1 - 4.8e-06 26.0 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding LexA_DNA_bind PF01726.16 KKK42078.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 LexA DNA binding domain Rrf2 PF02082.20 KKK42078.1 - 2.8e-05 24.4 0.0 6.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 KKK42078.1 - 4e-05 23.4 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.6 KKK42078.1 - 4e-05 23.5 0.1 8.9e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DUF2250 PF10007.9 KKK42078.1 - 5.2e-05 23.3 0.2 8.9e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_36 PF13730.6 KKK42078.1 - 9.1e-05 22.3 0.0 0.00025 21.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain CARD PF00619.21 KKK42078.1 - 0.00022 21.2 0.3 0.1 12.7 0.0 2.4 1 1 1 2 2 2 1 Caspase recruitment domain HTH_27 PF13463.6 KKK42078.1 - 0.0003 21.2 0.0 0.00078 19.9 0.0 1.8 2 0 0 2 2 1 1 Winged helix DNA-binding domain FeoC PF09012.10 KKK42078.1 - 0.00049 20.1 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 FeoC like transcriptional regulator HTH_5 PF01022.20 KKK42078.1 - 0.00052 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 KKK42078.1 - 0.00089 19.1 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Phage_rep_O PF04492.13 KKK42078.1 - 0.0015 19.1 0.1 0.0028 18.2 0.1 1.5 1 0 0 1 1 1 1 Bacteriophage replication protein O TFIIE_alpha PF02002.17 KKK42078.1 - 0.0018 18.1 0.4 0.0091 15.8 0.4 2.0 1 1 0 1 1 1 1 TFIIE alpha subunit HTH_IclR PF09339.10 KKK42078.1 - 0.0041 16.9 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain GerE PF00196.19 KKK42078.1 - 0.0057 16.2 0.1 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.6 KKK42078.1 - 0.012 15.4 0.0 0.071 12.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 KKK42078.1 - 0.014 15.5 0.2 0.023 14.9 0.2 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC AbiEi_4 PF13338.6 KKK42078.1 - 0.015 15.4 0.0 0.069 13.3 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin DUF505 PF04458.12 KKK42078.1 - 0.016 13.6 0.1 0.016 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Crp PF00325.20 KKK42078.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_1 PF00126.27 KKK42078.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_11 PF08279.12 KKK42078.1 - 0.024 14.6 0.0 0.082 12.9 0.0 2.0 1 1 1 2 2 2 0 HTH domain GntR PF00392.21 KKK42078.1 - 0.032 13.9 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family eIF-5_eIF-2B PF01873.17 KKK42078.1 - 0.04 13.8 0.6 2.1 8.3 0.3 2.1 1 1 1 2 2 2 0 Domain found in IF2B/IF5 HTH_29 PF13551.6 KKK42078.1 - 0.044 13.8 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 KKK42078.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 KKK42078.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Dimerisation PF08100.11 KKK42078.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain HTH_28 PF13518.6 KKK42078.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2258 PF10015.9 KKK42078.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) DUF4863 PF16155.5 KKK42078.1 - 0.12 12.2 0.0 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4863) Chordopox_A30L PF06015.12 KKK42079.1 - 0.015 15.2 0.8 0.026 14.4 0.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus A30L protein YgbA_NO PF11756.8 KKK42088.1 - 9.4e-42 141.7 4.4 1.1e-41 141.5 4.4 1.0 1 0 0 1 1 1 1 Nitrous oxide-stimulated promoter SH3_2 PF07653.17 KKK42091.1 - 4.9e-15 55.0 1.0 2.2e-07 30.4 0.1 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 KKK42091.1 - 1.5e-13 50.4 1.4 4e-06 26.6 0.1 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KKK42091.1 - 8.1e-12 44.6 4.6 1.9e-05 24.2 0.4 2.1 2 0 0 2 2 2 2 SH3 domain hSH3 PF14603.6 KKK42091.1 - 0.00065 20.1 0.0 0.52 10.8 0.0 2.1 1 1 1 2 2 2 2 Helically-extended SH3 domain SH3_3 PF08239.11 KKK42091.1 - 0.0019 18.4 8.4 0.037 14.3 1.9 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_16 PF18348.1 KKK42091.1 - 0.0096 15.7 0.2 0.73 9.7 0.1 2.5 2 1 0 2 2 2 1 Bacterial dipeptidyl-peptidase Sh3 domain SH3_4 PF06347.13 KKK42091.1 - 0.037 13.9 0.3 0.037 13.9 0.3 2.2 2 1 0 2 2 2 0 Bacterial SH3 domain ubiquitin PF00240.23 KKK42092.1 - 9.7e-09 34.9 0.0 1.4e-08 34.4 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KKK42092.1 - 0.044 13.6 0.1 0.11 12.3 0.1 1.7 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like XhlA PF10779.9 KKK42093.1 - 0.0056 16.9 1.7 0.0068 16.6 1.7 1.1 1 0 0 1 1 1 1 Haemolysin XhlA HSBP1 PF06825.12 KKK42093.1 - 0.012 15.4 0.7 0.014 15.2 0.7 1.1 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF5446 PF17522.2 KKK42093.1 - 0.015 15.4 0.4 0.02 15.1 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Enkurin PF13864.6 KKK42093.1 - 0.14 12.6 1.3 0.17 12.3 1.3 1.1 1 0 0 1 1 1 0 Calmodulin-binding MtrG PF04210.13 KKK42093.1 - 0.15 11.9 0.1 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G CCDC53 PF10152.9 KKK42093.1 - 0.18 12.2 0.9 0.21 12.0 0.6 1.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex SMN PF06003.12 KKK42093.1 - 7.1 5.8 8.7 7.8 5.7 8.7 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) HTH_45 PF14947.6 KKK42094.1 - 7.3e-05 22.7 4.0 0.0002 21.3 0.2 3.1 3 0 0 3 3 3 1 Winged helix-turn-helix MarR PF01047.22 KKK42094.1 - 0.0011 18.9 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 KKK42094.1 - 0.0011 18.7 0.0 0.0087 15.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF3935 PF13071.6 KKK42094.1 - 0.024 15.2 0.5 1.3 9.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3935) LPD11 PF18824.1 KKK42094.1 - 0.037 14.1 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 MerR_2 PF13591.6 KKK42094.1 - 0.049 13.5 0.7 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 MerR HTH family regulatory protein DDA1 PF10172.9 KKK42094.1 - 0.059 13.6 0.8 0.11 12.7 0.8 1.4 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase DUF1158 PF06643.11 KKK42095.1 - 0.13 12.7 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) LRR_4 PF12799.7 KKK42096.1 - 1.9e-19 69.5 30.0 1.7e-08 34.6 3.4 4.3 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK42096.1 - 6.7e-17 61.0 44.2 2.2e-07 30.5 8.1 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KKK42096.1 - 8.5e-06 25.4 7.9 0.00096 18.7 0.6 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 KKK42096.1 - 0.04 14.0 10.9 11 6.4 0.1 5.0 4 1 1 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 KKK42096.1 - 0.24 12.1 16.2 9.8 7.2 0.4 6.6 6 0 0 6 6 6 0 Leucine Rich Repeat NadA PF02445.16 KKK42097.1 - 5.4e-106 354.1 4.4 6.1e-106 353.9 4.4 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein Sigma70_r4_2 PF08281.12 KKK42097.1 - 0.084 12.6 0.2 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Glycos_transf_1 PF00534.20 KKK42100.1 - 2.1e-34 118.6 0.1 3.5e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK42100.1 - 3.3e-23 82.6 0.0 7.9e-23 81.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK42100.1 - 1.5e-17 64.2 0.0 2.1e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KKK42100.1 - 5.8e-11 42.6 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KKK42100.1 - 2.3e-07 31.4 0.0 3.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KKK42100.1 - 0.02 14.9 0.2 0.056 13.5 0.2 1.8 1 0 0 1 1 1 0 Glycosyl transferase 4-like GDP_Man_Dehyd PF16363.5 KKK42101.1 - 2.4e-58 198.1 0.0 2.9e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK42101.1 - 9e-56 189.0 0.0 1.1e-55 188.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK42101.1 - 9.8e-25 87.3 0.1 4.9e-24 85.0 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KKK42101.1 - 5.1e-22 78.2 0.1 6.4e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KKK42101.1 - 8.7e-15 54.6 0.0 2.6e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KKK42101.1 - 1.6e-08 34.0 0.0 2.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KKK42101.1 - 6.6e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KKK42101.1 - 0.0012 18.4 0.1 0.0023 17.4 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK42101.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KKK42101.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF150_C PF17384.2 KKK42101.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 RimP C-terminal SH3 domain UDPG_MGDP_dh_N PF03721.14 KKK42102.1 - 8.8e-34 116.7 0.0 8.6e-33 113.5 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KKK42102.1 - 9.1e-24 83.9 0.9 1.5e-23 83.2 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KKK42102.1 - 1.7e-21 76.2 0.0 4.2e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 KKK42102.1 - 4.5e-06 26.9 0.2 0.029 14.5 0.3 3.3 2 1 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.19 KKK42102.1 - 0.0061 15.9 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 KKK42102.1 - 0.028 14.8 0.0 5 7.6 0.0 2.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KKK42102.1 - 0.036 13.3 0.0 0.11 11.7 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pribosyltran PF00156.27 KKK42102.1 - 0.091 12.3 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 Phosphoribosyl transferase domain Pyr_redox PF00070.27 KKK42102.1 - 0.13 12.9 0.0 0.46 11.1 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KKK42102.1 - 0.14 12.8 0.3 4.6 7.9 0.0 2.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Response_reg PF00072.24 KKK42103.1 - 2.1e-23 82.6 0.2 2.4e-23 82.5 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_11 PF08241.12 KKK42104.1 - 1.4e-11 44.9 0.0 2.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK42104.1 - 5e-11 42.6 0.0 7.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK42104.1 - 3.1e-10 40.6 0.0 5.7e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK42104.1 - 9.3e-08 32.7 0.0 1.5e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK42104.1 - 3.5e-06 26.5 0.1 5.5e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 KKK42104.1 - 0.00019 20.9 0.1 0.00032 20.2 0.1 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 KKK42104.1 - 0.00057 19.8 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK42104.1 - 0.0028 17.4 0.0 0.0084 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KKK42104.1 - 0.0068 16.5 0.0 0.051 13.7 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KKK42104.1 - 0.028 14.4 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 KKK42104.1 - 0.051 13.3 2.9 0.32 10.7 0.2 2.5 2 1 1 3 3 3 0 DNA methylase Radical_SAM PF04055.21 KKK42105.1 - 1.2e-13 51.8 2.9 2e-13 51.0 0.1 2.4 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK42105.1 - 1.3e-08 35.2 2.0 1.3e-08 35.2 2.0 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK42105.1 - 0.00023 21.3 1.8 0.00023 21.3 1.8 2.6 2 1 1 3 3 3 1 4Fe-4S single cluster domain Ribosomal_S10 PF00338.22 KKK42106.1 - 6.4e-20 71.2 0.0 7e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Bactofilin PF04519.13 KKK42107.1 - 8.1e-11 42.1 21.3 2e-05 24.8 6.1 3.8 1 1 2 3 3 3 3 Polymer-forming cytoskeletal Inositol_P PF00459.25 KKK42108.1 - 1e-14 54.7 0.0 1.1e-14 54.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 KKK42108.1 - 1.1e-05 25.0 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain ATP-synt_F PF01990.17 KKK42108.1 - 0.012 15.9 0.1 0.018 15.4 0.1 1.3 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit FBPase_glpX PF03320.13 KKK42108.1 - 0.015 14.2 0.1 0.025 13.5 0.1 1.4 1 1 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded AMP-binding PF00501.28 KKK42111.1 - 3.6e-33 114.8 0.1 4.5e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK42111.1 - 7.9e-17 62.0 0.1 1.3e-16 61.3 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain pXO2-34 PF17362.2 KKK42111.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function NTP_transferase PF00483.23 KKK42112.1 - 1.9e-41 142.3 0.0 3e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KKK42112.1 - 2.3e-10 39.8 12.7 1.1e-08 34.5 6.5 3.8 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKK42112.1 - 4.3e-07 30.4 0.0 6.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KKK42112.1 - 6.5e-05 22.6 4.0 6.5e-05 22.6 4.0 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase MIT PF04212.18 KKK42113.1 - 4.8e-06 26.5 0.9 0.00044 20.2 0.0 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KKK42113.1 - 0.0021 18.1 0.7 1.3 9.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK42113.1 - 0.0022 17.7 0.6 3.7 7.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK42113.1 - 0.064 13.5 1.3 11 6.5 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1500 PF07389.12 KKK42113.1 - 0.087 12.9 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Chol_subst-bind PF09129.11 KKK42113.1 - 0.14 11.1 0.2 0.27 10.1 0.0 1.5 2 0 0 2 2 2 0 Cholesterol oxidase, substrate-binding RRF_GI PF12614.8 KKK42113.1 - 7.8 6.7 7.8 1.2 9.3 0.4 3.0 2 2 1 3 3 3 0 Ribosome recycling factor DUF1953 PF09196.10 KKK42114.1 - 0.041 13.7 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) Ribosomal_S4 PF00163.19 KKK42114.1 - 0.1 13.5 0.8 0.15 13.0 0.8 1.5 1 1 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Bac_luciferase PF00296.20 KKK42115.1 - 4.3e-48 164.4 0.0 2.6e-47 161.8 0.0 1.7 1 1 1 2 2 2 2 Luciferase-like monooxygenase CYTH PF01928.21 KKK42116.1 - 1e-20 74.4 2.2 1.2e-20 74.2 2.2 1.0 1 0 0 1 1 1 1 CYTH domain Methyltr_RsmB-F PF01189.17 KKK42117.1 - 3.4e-55 186.8 0.0 4.3e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KKK42117.1 - 1.2e-12 48.2 0.0 2.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KKK42117.1 - 0.0084 16.2 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 KKK42117.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0113 PF03657.13 KKK42118.1 - 9.3e-15 54.7 0.1 1.7e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 KKK42118.1 - 4.9e-09 36.6 0.5 1.1e-08 35.5 0.1 1.8 2 0 0 2 2 2 1 UPF0113 Pre-PUA domain EAP30 PF04157.16 KKK42119.1 - 3e-15 56.2 1.7 4.2e-15 55.7 1.7 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family NeuB PF03102.14 KKK42119.1 - 0.0046 16.4 0.5 0.0073 15.8 0.5 1.3 1 0 0 1 1 1 1 NeuB family HEPN-like_int PF18867.1 KKK42119.1 - 0.05 13.5 2.2 0.27 11.1 0.2 2.5 1 1 1 2 2 2 0 HEPN-like integron domain ESCRT-II PF05871.12 KKK42120.1 - 1.3e-11 44.9 5.5 3.1e-11 43.7 4.3 2.2 1 1 1 2 2 2 1 ESCRT-II complex subunit Translin PF01997.16 KKK42120.1 - 0.09 12.8 5.5 0.18 11.8 5.3 1.9 1 1 0 1 1 1 0 Translin family HGD-D PF06050.13 KKK42120.1 - 6.4 6.4 8.8 1.1e+02 2.3 8.8 2.1 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component AAA PF00004.29 KKK42121.1 - 3.5e-40 137.5 0.0 6.1e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 KKK42121.1 - 1.4e-12 47.4 0.7 3e-12 46.4 0.7 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KKK42121.1 - 1.5e-09 37.5 0.0 3.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KKK42121.1 - 3e-06 27.1 0.1 7.6e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KKK42121.1 - 2e-05 24.4 0.0 3.6e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK42121.1 - 0.00039 20.9 0.1 0.0016 18.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KKK42121.1 - 0.0028 17.8 0.0 0.0061 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK42121.1 - 0.0033 17.7 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKK42121.1 - 0.0037 17.3 0.0 0.016 15.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KKK42121.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 KKK42121.1 - 0.011 15.7 0.0 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 KKK42121.1 - 0.014 14.7 0.1 0.033 13.4 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KKK42121.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KKK42121.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KKK42121.1 - 0.027 15.0 0.0 0.058 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KKK42121.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KKK42121.1 - 0.062 13.7 0.0 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KKK42121.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 KKK42121.1 - 0.16 11.8 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_25 PF13481.6 KKK42121.1 - 0.2 11.2 0.1 0.45 10.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Snf7 PF03357.21 KKK42122.1 - 1.2e-11 44.5 8.8 1.2e-11 44.5 8.8 1.8 1 1 1 2 2 2 1 Snf7 RPN13_C PF16550.5 KKK42122.1 - 0.017 15.3 0.6 1.8 8.8 0.1 2.3 1 1 1 2 2 2 0 UCH-binding domain DUF2379 PF09543.10 KKK42122.1 - 0.048 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) DUF1664 PF07889.12 KKK42122.1 - 0.81 9.7 6.5 0.37 10.8 3.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 KKK42122.1 - 1.2 9.3 8.5 1.4e+02 2.6 8.5 2.8 1 1 0 1 1 1 0 Up-regulated During Septation Mst1_SARAH PF11629.8 KKK42122.1 - 2.4 8.3 5.1 1.6 8.8 0.1 2.9 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 PfkB PF00294.24 KKK42123.1 - 1.7e-42 145.7 0.0 2.3e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Methyltransf_11 PF08241.12 KKK42124.1 - 3.7e-15 56.3 0.0 6.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK42124.1 - 1.8e-12 47.8 0.0 3.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK42124.1 - 5.4e-09 36.0 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK42124.1 - 7.7e-08 32.3 0.0 1.2e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK42124.1 - 1.5e-07 31.0 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK42124.1 - 7.2e-07 29.9 0.0 1.3e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KKK42124.1 - 0.023 14.5 0.0 0.097 12.5 0.0 1.9 1 1 1 2 2 2 0 Hypothetical methyltransferase CMAS PF02353.20 KKK42124.1 - 0.04 13.2 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SinI PF08671.10 KKK42124.1 - 0.076 12.8 0.4 0.29 11.0 0.1 2.2 2 0 0 2 2 2 0 Anti-repressor SinI THUMP PF02926.17 KKK42129.1 - 0.026 14.6 0.2 0.029 14.5 0.2 1.1 1 0 0 1 1 1 0 THUMP domain DUF3449 PF11931.8 KKK42129.1 - 0.043 13.6 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) PurS PF02700.14 KKK42129.1 - 0.065 13.4 1.1 0.12 12.6 0.2 1.8 1 1 1 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase AAA_15 PF13175.6 KKK42130.1 - 1.5e-18 67.7 7.1 1.5e-11 44.7 2.7 2.2 1 1 1 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KKK42130.1 - 4.6e-17 62.8 1.6 9.7e-08 32.2 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF2813 PF11398.8 KKK42130.1 - 1.7e-12 47.3 0.7 6.4e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2813) SMC_N PF02463.19 KKK42130.1 - 7.8e-09 35.3 0.1 2.3e-08 33.8 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK42130.1 - 5e-05 23.9 2.1 8.3e-05 23.2 0.8 1.9 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KKK42130.1 - 0.00046 19.8 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK42130.1 - 0.00077 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KKK42130.1 - 0.0014 19.1 0.1 0.0072 16.8 0.1 2.1 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 KKK42130.1 - 0.0019 18.2 0.1 0.098 12.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KKK42130.1 - 0.85 9.7 2.8 0.58 10.2 0.2 1.9 3 0 0 3 3 3 0 Dynamin family Orbi_VP6 PF01516.16 KKK42131.1 - 0.048 13.2 0.1 0.068 12.7 0.1 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 SecD-TM1 PF13721.6 KKK42131.1 - 0.057 13.9 0.0 4.1 7.9 0.0 2.2 2 0 0 2 2 2 0 SecD export protein N-terminal TM region Histone_HNS PF00816.21 KKK42131.1 - 0.13 13.1 0.1 2.7 8.9 0.0 2.2 2 0 0 2 2 2 0 H-NS histone family Fe-ADH_2 PF13685.6 KKK42131.1 - 0.23 11.2 0.0 1.2 8.7 0.0 1.9 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase WH1 PF00568.23 KKK42132.1 - 1.4 8.8 8.3 8.4 6.4 0.7 4.5 4 2 0 4 4 4 0 WH1 domain Beta-lactamase PF00144.24 KKK42133.1 - 4.6e-59 200.3 0.0 6.9e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Pab87_oct PF13969.6 KKK42133.1 - 9.3e-15 54.5 0.0 1.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Pab87 octamerisation domain MFS_1 PF07690.16 KKK42134.1 - 4.6e-19 68.5 43.1 2.7e-15 56.1 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KKK42134.1 - 0.1 11.0 3.1 0.44 8.9 0.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Glyoxalase PF00903.25 KKK42135.1 - 9.1e-09 35.6 0.0 1.2e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3-dmu-9_3-mt PF06983.13 KKK42135.1 - 0.0081 16.7 0.0 0.013 16.0 0.0 1.4 1 1 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Abhydrolase_1 PF00561.20 KKK42136.1 - 8e-27 94.5 0.0 1e-26 94.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK42136.1 - 7.1e-13 49.7 0.0 9.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK42136.1 - 3.1e-06 26.6 0.0 0.00073 18.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 KKK42136.1 - 0.0015 17.3 0.0 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 KKK42136.1 - 0.13 12.1 0.0 17 5.2 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family AMP-binding PF00501.28 KKK42137.1 - 4.5e-95 318.7 0.0 5.3e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK42137.1 - 4.9e-18 65.9 0.0 8.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MT PF12777.7 KKK42137.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor TAF6_C PF07571.13 KKK42137.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain DUF1002 PF06207.11 KKK42138.1 - 0.42 10.1 3.1 0.46 10.0 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) dCMP_cyt_deam_1 PF00383.23 KKK42139.1 - 1.7e-23 82.4 0.5 2.1e-23 82.1 0.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KKK42139.1 - 1e-17 64.2 0.1 1.2e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KKK42139.1 - 0.018 15.1 0.1 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KKK42139.1 - 0.12 12.4 0.4 0.17 12.0 0.4 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 ECH_1 PF00378.20 KKK42140.1 - 3.7e-60 203.3 0.0 5.1e-40 137.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK42140.1 - 6.7e-34 117.9 0.0 3e-30 105.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Response_reg PF00072.24 KKK42141.1 - 1.4e-22 80.0 1.6 1.6e-22 79.8 1.6 1.0 1 0 0 1 1 1 1 Response regulator receiver domain GIDE PF12483.8 KKK42141.1 - 0.15 11.4 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 E3 Ubiquitin ligase Prenyltransf PF01255.19 KKK42142.1 - 2e-54 184.5 0.0 2.3e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CSTF_C PF14304.6 KKK42142.1 - 0.16 11.6 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal FixG_C PF11614.8 KKK42143.1 - 0.009 16.2 0.2 0.026 14.8 0.2 1.8 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase TIR PF01582.20 KKK42143.1 - 0.013 15.4 0.2 0.039 13.8 0.2 1.9 1 0 0 1 1 1 0 TIR domain DUF2935 PF11155.8 KKK42143.1 - 0.046 14.1 6.2 0.29 11.5 4.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) GCS2 PF04107.13 KKK42144.1 - 0.017 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) DUF327 PF03885.13 KKK42144.1 - 0.14 12.1 1.0 0.37 10.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF327) RdgC PF04381.12 KKK42145.1 - 0.032 13.5 0.0 0.032 13.5 0.0 1.0 1 0 0 1 1 1 0 Putative exonuclease, RdgC Amidohydro_2 PF04909.14 KKK42146.1 - 2.6e-05 24.2 0.3 0.00021 21.2 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase DUF1499 PF07386.11 KKK42146.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1499) KASH_CCD PF14662.6 KKK42147.1 - 7.2e-05 22.7 34.2 0.02 14.8 8.0 2.8 1 1 2 3 3 3 3 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KKK42147.1 - 0.0073 16.8 31.0 0.031 14.8 6.1 3.2 1 1 2 3 3 3 2 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KKK42147.1 - 0.011 15.7 32.3 0.18 11.8 6.6 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 z-alpha PF02295.17 KKK42147.1 - 0.016 15.2 3.1 0.016 15.2 3.1 2.4 2 1 0 2 2 1 0 Adenosine deaminase z-alpha domain DUF948 PF06103.11 KKK42147.1 - 0.11 12.7 0.2 0.11 12.7 0.2 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 KKK42147.1 - 0.36 10.9 31.5 0.94 9.5 4.5 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding BST2 PF16716.5 KKK42147.1 - 0.37 11.4 0.1 0.37 11.4 0.1 4.1 1 1 4 5 5 4 0 Bone marrow stromal antigen 2 Atg14 PF10186.9 KKK42147.1 - 0.42 9.6 28.6 0.063 12.4 6.8 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 KKK42147.1 - 0.54 10.4 0.1 0.54 10.4 0.1 4.5 3 1 0 4 4 4 0 bZIP transcription factor UPF0242 PF06785.11 KKK42147.1 - 0.55 10.3 33.2 0.092 12.8 10.3 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 KKK42147.1 - 1 10.0 30.5 0.2 12.3 2.9 4.1 1 1 2 3 3 3 0 Initiation control protein YabA GAS PF13851.6 KKK42147.1 - 1 8.6 35.6 0.89 8.9 18.6 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 KKK42147.1 - 1.1 9.1 39.1 2.1 8.2 0.1 6.0 1 1 5 6 6 6 0 Septum formation initiator CENP-H PF05837.12 KKK42147.1 - 1.2 9.6 27.5 1.8 9.0 13.1 3.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DASH_Dam1 PF08653.10 KKK42147.1 - 1.5 8.7 3.7 49 3.8 0.3 3.8 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF3450 PF11932.8 KKK42147.1 - 1.7 7.9 25.5 0.93 8.7 4.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) PI3K_P85_iSH2 PF16454.5 KKK42147.1 - 2.1 8.0 33.8 0.42 10.2 7.3 3.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4349 PF14257.6 KKK42147.1 - 2.2 7.7 10.0 2.4 7.6 4.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF4618 PF15397.6 KKK42147.1 - 2.9 7.3 28.9 1.2 8.4 14.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DUF1664 PF07889.12 KKK42147.1 - 5.2 7.1 19.8 5.3 7.1 3.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 KKK42147.1 - 6.1 7.1 27.8 4.4 7.6 3.3 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 KKK42152.1 - 0.0014 18.0 45.9 0.0041 16.5 18.4 3.6 1 1 3 4 4 4 1 Domain of unknown function (DUF4407) SlyX PF04102.12 KKK42152.1 - 0.011 16.3 10.1 0.011 16.3 10.1 6.7 4 2 2 6 6 6 0 SlyX Phage_holin_3_6 PF07332.11 KKK42152.1 - 0.091 12.8 1.6 0.14 12.2 0.5 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ERM PF00769.19 KKK42152.1 - 0.37 10.6 90.2 0.64 9.8 18.3 4.1 2 2 2 4 4 4 0 Ezrin/radixin/moesin family ATG16 PF08614.11 KKK42152.1 - 0.42 10.8 75.7 0.033 14.4 18.5 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 KKK42152.1 - 7.5 4.9 8.7 1.7 7.1 0.8 2.3 1 1 0 2 2 2 0 Fusaric acid resistance protein family PfkB PF00294.24 KKK42153.1 - 2.3e-49 168.4 0.0 2.6e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KKK42153.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase UBM PF14377.6 KKK42153.1 - 0.3 10.6 0.6 0.67 9.5 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin binding region Apolipoprotein PF01442.18 KKK42154.1 - 3e-10 40.3 29.0 3.2e-07 30.4 18.0 2.7 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain ApoO PF09769.9 KKK42154.1 - 0.0011 19.0 18.4 0.0073 16.3 1.4 5.0 1 1 3 4 4 4 1 Apolipoprotein O Baculo_PEP_C PF04513.12 KKK42154.1 - 0.0016 18.5 9.0 0.0016 18.5 9.0 4.6 1 1 4 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 KKK42154.1 - 0.044 14.4 20.9 0.45 11.1 5.0 5.0 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF4455 PF14643.6 KKK42154.1 - 0.28 9.8 47.6 0.34 9.5 7.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4455) DUF4407 PF14362.6 KKK42154.1 - 0.35 10.2 37.1 0.93 8.8 20.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) FAM184 PF15665.5 KKK42154.1 - 0.43 10.3 45.3 0.51 10.1 26.3 2.8 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Prominin PF05478.11 KKK42154.1 - 0.69 7.8 55.1 0.014 13.4 10.9 3.1 1 1 1 2 2 2 0 Prominin DUF3584 PF12128.8 KKK42154.1 - 1.2 6.5 47.5 1.7 6.0 36.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) V-ATPase_G_2 PF16999.5 KKK42154.1 - 1.2 9.5 15.8 5.3 7.5 0.0 4.8 1 1 4 5 5 5 0 Vacuolar (H+)-ATPase G subunit Filament PF00038.21 KKK42154.1 - 2.3 7.7 51.5 0.75 9.3 3.2 3.7 1 1 2 3 3 3 0 Intermediate filament protein Myb_CC_LHEQLE PF14379.6 KKK42154.1 - 2.6 7.8 16.7 2.6 7.8 2.0 4.0 1 1 2 3 3 3 0 MYB-CC type transfactor, LHEQLE motif DUF2325 PF10087.9 KKK42154.1 - 2.7 8.1 12.3 18 5.5 0.1 4.5 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2325) V_ATPase_I_N PF18670.1 KKK42154.1 - 2.8 8.4 5.3 14 6.1 0.4 3.6 3 1 0 3 3 3 0 V-type ATPase subunit I, N-terminal domain Fzo_mitofusin PF04799.13 KKK42154.1 - 3.1 7.3 45.6 0.86 9.1 4.0 4.9 1 1 1 4 4 4 0 fzo-like conserved region K1 PF02960.14 KKK42154.1 - 3.5 7.8 8.3 31 4.7 2.0 3.9 1 1 2 4 4 4 0 K1 glycoprotein OmpH PF03938.14 KKK42154.1 - 5.6 7.3 56.8 8.8 6.7 25.2 4.1 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) PriC PF07445.12 KKK42154.1 - 5.8 6.8 40.8 12 5.8 3.0 4.1 1 1 2 3 3 3 0 Primosomal replication protein priC Utp12 PF04003.12 KKK42154.1 - 5.8 7.3 17.4 1.4 9.2 1.7 4.7 1 1 5 6 6 6 0 Dip2/Utp12 Family GldM_N PF12081.8 KKK42154.1 - 7.1 6.7 51.9 1.1 9.3 7.6 4.7 1 1 4 5 5 5 0 GldM N-terminal domain EzrA PF06160.12 KKK42154.1 - 8.5 4.4 64.2 8 4.5 43.6 2.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HisKA_3 PF07730.13 KKK42154.1 - 8.6 7.0 10.2 3.6 8.2 0.3 4.3 3 2 1 4 4 4 0 Histidine kinase HD_assoc PF13286.6 KKK42154.1 - 9.5 6.8 7.2 2.4 8.7 0.2 3.1 3 1 0 3 3 3 0 Phosphohydrolase-associated domain Ras PF00071.22 KKK42155.1 - 3.5e-31 108.0 0.0 6.9e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42155.1 - 3.4e-26 91.8 0.6 2.4e-25 89.1 0.1 2.5 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42155.1 - 1e-11 44.6 0.1 1e-11 44.6 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42155.1 - 2.9e-08 33.4 0.1 5.7e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK42155.1 - 1.7e-06 28.1 5.5 0.00052 19.9 0.2 3.0 2 2 2 4 4 4 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK42155.1 - 1.7e-05 24.8 0.3 1.7e-05 24.8 0.3 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK42155.1 - 0.00017 21.2 2.6 0.00028 20.5 0.4 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain YABBY PF04690.13 KKK42155.1 - 0.12 12.9 0.2 0.24 12.0 0.2 1.4 1 0 0 1 1 1 0 YABBY protein Dynamin_N PF00350.23 KKK42155.1 - 0.79 9.8 8.4 11 6.0 8.4 2.9 1 1 0 1 1 1 0 Dynamin family NMO PF03060.15 KKK42156.1 - 1.3e-45 156.3 0.0 6.2e-45 154.0 0.0 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK42156.1 - 1.3e-11 44.2 1.7 4.8e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK42156.1 - 9.7e-10 38.0 0.4 2.6e-09 36.6 0.4 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1729 PF08354.10 KKK42156.1 - 0.034 13.0 0.1 0.1 11.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) SGL PF08450.12 KKK42157.1 - 5.2e-50 170.3 0.0 5.9e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF4915 PF16261.5 KKK42157.1 - 5.2e-07 29.2 0.0 7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4915) Str_synth PF03088.16 KKK42157.1 - 3.7e-05 23.8 0.0 0.00049 20.2 0.0 2.5 2 0 0 2 2 2 1 Strictosidine synthase NHL PF01436.21 KKK42157.1 - 3.9e-05 23.5 4.1 0.04 14.0 0.4 4.4 4 0 0 4 4 4 1 NHL repeat Reg_prop PF07494.11 KKK42157.1 - 0.0019 18.2 1.8 1.3 9.5 0.0 4.5 5 0 0 5 5 5 1 Two component regulator propeller Arylesterase PF01731.20 KKK42157.1 - 0.0071 16.5 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Arylesterase DUF5122 PF17164.4 KKK42157.1 - 0.0091 16.3 0.3 6.8 7.1 0.0 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF5122) beta-propeller Phytase-like PF13449.6 KKK42157.1 - 0.011 15.7 0.0 0.94 9.4 0.0 2.5 2 2 0 2 2 2 0 Esterase-like activity of phytase Lactonase PF10282.9 KKK42157.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Zip PF02535.22 KKK42158.1 - 3.3e-35 121.9 18.0 1e-27 97.2 11.1 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter FtsX PF02687.21 KKK42158.1 - 3.5 8.2 18.8 3.6 8.1 6.7 2.8 2 2 0 2 2 2 0 FtsX-like permease family ECF-ribofla_trS PF07155.12 KKK42159.1 - 3.2e-37 128.2 16.5 4.1e-37 127.8 16.5 1.0 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component ECF_trnsprt PF12822.7 KKK42159.1 - 9.8e-06 25.8 21.8 1.4e-05 25.2 21.8 1.2 1 0 0 1 1 1 1 ECF transporter, substrate-specific component 5TM-5TMR_LYT PF07694.12 KKK42159.1 - 0.0032 17.0 12.4 0.0057 16.2 12.4 1.4 1 1 0 1 1 1 1 5TMR of 5TMR-LYT DUF2456 PF10445.9 KKK42159.1 - 2.2 8.4 5.9 0.33 11.1 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2456) DUF1363 PF07101.11 KKK42164.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1363) Pur_DNA_glyco PF02245.16 KKK42166.1 - 3.9e-58 195.8 0.0 4.4e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) URO-D PF01208.17 KKK42167.1 - 2.7e-29 102.4 0.0 4.3e-28 98.4 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) Inositol_P PF00459.25 KKK42169.1 - 5.6e-29 101.5 0.0 7.2e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 KKK42169.1 - 1.6e-05 24.4 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain FBPase_glpX PF03320.13 KKK42169.1 - 0.041 12.7 0.1 0.083 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Bactofilin PF04519.13 KKK42171.1 - 1.3e-11 44.6 22.0 1e-06 28.9 6.2 3.7 1 1 2 3 3 3 3 Polymer-forming cytoskeletal Radical_SAM PF04055.21 KKK42172.1 - 1.3e-10 41.9 1.4 7.5e-10 39.4 0.1 2.5 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK42172.1 - 5.8e-10 39.6 2.1 5.8e-10 39.6 2.1 2.4 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK42172.1 - 4.6e-05 23.5 1.5 4.6e-05 23.5 1.5 2.7 2 1 1 3 3 3 1 4Fe-4S single cluster domain Stn1 PF10451.9 KKK42172.1 - 0.051 12.5 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Methyltransf_31 PF13847.6 KKK42173.1 - 4.4e-10 39.6 0.1 6.3e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK42173.1 - 6.7e-10 39.5 0.0 1.3e-09 38.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK42173.1 - 6.2e-09 36.4 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK42173.1 - 2e-06 28.5 0.0 3.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK42173.1 - 5.9e-06 25.8 0.1 7.3e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KKK42173.1 - 0.00018 21.4 0.0 0.00045 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KKK42173.1 - 0.00042 20.5 0.0 0.0017 18.5 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 KKK42173.1 - 0.00076 19.3 0.0 0.0021 17.8 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KKK42173.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KKK42173.1 - 0.0034 16.8 0.1 0.006 16.0 0.1 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 KKK42173.1 - 0.049 13.5 0.2 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase N6_N4_Mtase PF01555.18 KKK42173.1 - 0.14 11.8 2.6 0.33 10.6 0.2 2.3 2 1 1 3 3 3 0 DNA methylase Response_reg PF00072.24 KKK42174.1 - 3e-17 62.8 0.1 3.4e-17 62.6 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain IpaB_EvcA PF03278.13 KKK42174.1 - 0.031 14.0 0.2 0.036 13.8 0.2 1.1 1 0 0 1 1 1 0 IpaB/EvcA family ADH_zinc_N PF00107.26 KKK42174.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase IHO1 PF15771.5 KKK42176.1 - 0.0082 15.0 0.7 0.0098 14.7 0.7 1.0 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 BAG6 PF12057.8 KKK42176.1 - 0.014 15.1 0.2 0.017 14.8 0.2 1.1 1 0 0 1 1 1 0 BCL2-associated athanogene 6 SKA2 PF16740.5 KKK42176.1 - 0.019 14.7 1.2 0.022 14.5 1.2 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Cnn_1N PF07989.11 KKK42176.1 - 0.023 14.8 3.3 0.041 14.0 3.3 1.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ACCA PF03255.14 KKK42176.1 - 0.042 13.7 1.2 0.047 13.6 1.2 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HTH_Tnp_Tc3_2 PF01498.18 KKK42176.1 - 0.057 13.7 0.8 6.5 7.1 0.1 2.2 1 1 1 2 2 2 0 Transposase BORCS8 PF10167.9 KKK42176.1 - 0.078 12.9 0.7 0.093 12.7 0.7 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 DUF948 PF06103.11 KKK42176.1 - 0.084 13.1 1.3 0.12 12.6 1.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 KKK42176.1 - 0.11 12.9 2.9 0.15 12.4 2.9 1.2 1 0 0 1 1 1 0 Syntaxin-like protein EOS1 PF12326.8 KKK42177.1 - 0.015 15.2 2.6 0.016 15.1 2.6 1.0 1 0 0 1 1 1 0 N-glycosylation protein Phage_holin_3_6 PF07332.11 KKK42177.1 - 0.032 14.3 0.5 0.035 14.1 0.5 1.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III zf-RING_4 PF14570.6 KKK42178.1 - 4.9e-06 26.2 15.7 6.1e-06 25.9 15.7 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 KKK42178.1 - 0.00021 21.5 10.4 0.00023 21.4 10.4 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger zf-UDP PF14569.6 KKK42178.1 - 0.0094 16.1 8.0 0.011 15.9 8.0 1.1 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RanBP PF00641.18 KKK42178.1 - 0.046 13.0 2.9 0.046 13.0 2.9 2.8 3 1 0 3 3 3 0 Zn-finger in Ran binding protein and others Prim_Zn_Ribbon PF08273.12 KKK42178.1 - 0.3 11.4 0.2 0.3 11.4 0.2 2.8 1 1 1 3 3 3 0 Zinc-binding domain of primase-helicase zf-C3HC4_4 PF15227.6 KKK42178.1 - 1.7 8.9 14.9 7.2 6.9 14.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3039 PF11238.8 KKK42178.1 - 8 6.3 10.9 1.7 8.5 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) DSBA PF01323.20 KKK42179.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain CitMHS PF03600.16 KKK42181.1 - 1.8e-35 122.6 58.1 1e-31 110.3 39.9 2.7 1 1 1 2 2 2 2 Citrate transporter ArsB PF02040.15 KKK42181.1 - 6.3e-10 38.9 38.9 8.4e-10 38.5 38.9 1.1 1 0 0 1 1 1 1 Arsenical pump membrane protein MatC_N PF07158.11 KKK42181.1 - 0.00088 19.3 15.5 0.00088 19.3 15.5 3.1 2 1 0 2 2 2 1 Dicarboxylate carrier protein MatC N-terminus ELFV_dehydrog PF00208.21 KKK42182.1 - 2.7e-68 230.3 0.2 3.8e-68 229.8 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KKK42182.1 - 4.1e-53 178.7 0.0 8.4e-53 177.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KKK42182.1 - 0.0049 16.2 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_20 PF14691.6 KKK42183.1 - 1.4e-38 131.1 1.1 1.4e-38 131.1 1.1 3.0 2 1 1 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 KKK42183.1 - 8.2e-38 130.3 0.0 1.3e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FrhB_FdhB_C PF04432.13 KKK42183.1 - 4.7e-36 124.0 0.2 1.9e-35 122.0 0.0 2.2 2 0 0 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK42183.1 - 8.8e-21 73.9 0.0 2.2e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Pyr_redox PF00070.27 KKK42183.1 - 1.5e-12 47.9 0.4 2.2e-05 24.9 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK42183.1 - 4.7e-10 39.2 0.0 9.5e-05 21.8 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK42183.1 - 3.7e-08 33.5 0.9 1.7e-07 31.4 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KKK42183.1 - 3.3e-06 26.5 0.0 0.072 12.4 0.0 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KKK42183.1 - 4.8e-05 22.7 0.3 0.00094 18.5 0.1 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KKK42183.1 - 6.8e-05 22.3 0.1 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Fer4_9 PF13187.6 KKK42183.1 - 8.4e-05 22.7 12.2 8.4e-05 22.7 12.2 3.6 3 0 0 3 3 2 2 4Fe-4S dicluster domain DAO PF01266.24 KKK42183.1 - 0.00015 21.5 0.4 0.00064 19.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Fer4_7 PF12838.7 KKK42183.1 - 0.00017 22.1 26.1 0.0051 17.4 13.2 3.4 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK42183.1 - 0.00052 19.7 6.8 0.00052 19.7 6.8 4.6 4 1 0 4 4 4 2 4Fe-4S binding domain FAD_oxidored PF12831.7 KKK42183.1 - 0.00055 19.4 1.6 0.0033 16.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK42183.1 - 0.00059 19.0 5.1 0.0012 18.0 0.4 2.7 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KKK42183.1 - 0.00067 18.5 2.1 0.00079 18.2 0.5 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KKK42183.1 - 0.0007 18.8 0.5 0.015 14.4 0.1 2.6 3 0 0 3 3 2 1 Glucose inhibited division protein A Fer4_10 PF13237.6 KKK42183.1 - 0.0012 19.0 33.4 0.052 13.7 2.8 4.0 2 2 1 3 3 3 2 4Fe-4S dicluster domain NAD_binding_7 PF13241.6 KKK42183.1 - 0.0092 16.4 0.1 5.3 7.5 0.0 3.2 3 1 0 3 3 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 KKK42183.1 - 0.014 14.8 1.6 0.042 13.1 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Fer4_17 PF13534.6 KKK42183.1 - 0.033 14.7 23.9 0.15 12.6 0.8 4.2 3 1 1 4 4 3 0 4Fe-4S dicluster domain DUF4145 PF13643.6 KKK42183.1 - 0.035 14.2 0.4 0.11 12.7 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Fer4_13 PF13370.6 KKK42183.1 - 0.067 13.7 0.6 0.067 13.7 0.6 3.3 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I XdhC_C PF13478.6 KKK42183.1 - 0.07 13.6 0.3 5.8 7.4 0.0 3.2 4 0 0 4 4 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 KKK42183.1 - 0.1 11.6 0.1 0.45 9.5 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Fer4_8 PF13183.6 KKK42183.1 - 0.17 12.3 25.3 0.21 12.1 0.3 4.0 3 1 1 4 4 4 0 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 KKK42183.1 - 0.22 11.5 0.3 0.53 10.3 0.2 1.7 2 0 0 2 2 1 0 FAD-NAD(P)-binding Fer4_18 PF13746.6 KKK42183.1 - 0.23 11.6 15.5 0.93 9.7 0.0 3.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK42183.1 - 0.35 11.0 34.1 0.07 13.3 5.9 3.9 2 2 1 4 4 4 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK42183.1 - 0.93 10.2 35.9 0.61 10.7 2.5 4.5 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK42183.1 - 1.6 9.0 31.5 0.25 11.5 1.1 4.1 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK42183.1 - 3.1 8.7 18.4 6.1 7.8 3.9 3.8 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK42183.1 - 6.6 7.0 39.3 0.056 13.5 4.0 4.0 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 KKK42183.1 - 9.4 7.1 9.4 9.8 7.0 0.5 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain DHODB_Fe-S_bind PF10418.9 KKK42184.1 - 4.1e-10 39.3 0.9 7.5e-10 38.5 0.9 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NAD_binding_1 PF00175.21 KKK42184.1 - 0.045 14.4 0.0 0.1 13.3 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain GMP_synt_C PF00958.22 KKK42185.1 - 5.4e-42 141.8 0.1 9.9e-42 140.9 0.1 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KKK42185.1 - 2.7e-36 125.1 0.0 5.2e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KKK42185.1 - 4.8e-10 39.0 0.0 3.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KKK42185.1 - 2.6e-07 30.6 0.0 1.7e-06 28.0 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.13 KKK42185.1 - 2.4e-05 24.0 0.0 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KKK42185.1 - 2.8e-05 23.1 0.0 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 KKK42185.1 - 0.0047 16.5 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 KKK42185.1 - 0.035 14.1 0.0 0.093 12.8 0.0 1.8 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.21 KKK42185.1 - 0.099 12.3 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Asparagine synthase Peptidase_M3_N PF08439.10 KKK42186.1 - 2.8e-08 33.9 0.0 1.2e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Oligopeptidase F LZ3wCH PF18517.1 KKK42186.1 - 0.05 13.7 0.2 0.17 12.0 0.2 1.9 1 0 0 1 1 1 0 Leucine zipper with capping helix domain nsp7 PF08716.10 KKK42186.1 - 0.17 12.5 0.1 0.48 11.1 0.1 1.7 1 0 0 1 1 1 0 nsp7 replicase Ras PF00071.22 KKK42189.1 - 4.6e-50 169.4 0.9 6.8e-50 168.8 0.9 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42189.1 - 3.7e-30 104.6 0.3 6.2e-30 103.9 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42189.1 - 2.5e-14 53.1 0.3 4.3e-14 52.3 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42189.1 - 2.2e-06 27.2 0.1 3.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK42189.1 - 3.4e-06 27.1 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK42189.1 - 4.7e-05 23.4 0.5 0.097 12.6 0.1 2.5 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KKK42189.1 - 5.4e-05 22.8 0.1 0.00019 21.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KKK42189.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B NB-ARC PF00931.22 KKK42189.1 - 0.011 14.9 0.6 0.023 13.9 0.6 1.6 1 1 0 1 1 1 0 NB-ARC domain Robl_LC7 PF03259.17 KKK42189.1 - 0.015 15.0 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Roadblock/LC7 domain AAA_16 PF13191.6 KKK42189.1 - 0.039 14.3 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 KKK42189.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 KKK42189.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Lactamase_B PF00753.27 KKK42193.1 - 3.3e-09 37.0 0.1 6.4e-09 36.1 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK42193.1 - 0.0037 16.8 0.0 0.0053 16.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DZR PF12773.7 KKK42194.1 - 0.014 15.4 1.5 0.023 14.7 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK42194.1 - 0.03 14.1 5.4 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain G0-G1_switch_2 PF15103.6 KKK42194.1 - 0.063 13.7 0.1 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 G0/G1 switch protein 2 Phage_holin_5_2 PF16079.5 KKK42194.1 - 0.16 12.3 11.1 0.61 10.5 0.2 3.2 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V Claudin_2 PF13903.6 KKK42194.1 - 0.82 9.4 5.7 0.13 12.0 1.5 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction zf-ribbon_3 PF13248.6 KKK42194.1 - 1.1 8.8 4.4 5.8 6.5 4.4 2.0 1 1 0 1 1 1 0 zinc-ribbon domain Pox_A14 PF05767.12 KKK42194.1 - 2.1 8.6 6.7 0.67 10.2 0.8 2.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Nudix_N_2 PF14803.6 KKK42194.1 - 3.2 7.7 5.9 12 6.0 0.9 2.3 2 0 0 2 2 2 0 Nudix N-terminal DUF4064 PF13273.6 KKK42194.1 - 8.6 6.7 19.1 7.8 6.8 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) EcKinase PF02958.20 KKK42195.1 - 0.014 14.8 0.0 0.026 13.8 0.0 1.3 1 1 0 1 1 1 0 Ecdysteroid kinase MM_CoA_mutase PF01642.22 KKK42197.1 - 2.1e-163 544.6 0.0 2.4e-163 544.4 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase Imm27 PF15590.6 KKK42197.1 - 0.16 11.7 1.3 0.59 9.9 1.3 2.0 1 0 0 1 1 1 0 Immunity protein 27 B12-binding PF02310.19 KKK42198.1 - 2.3e-16 59.9 0.2 2.7e-16 59.7 0.2 1.1 1 0 0 1 1 1 1 B12 binding domain MeaB PF03308.16 KKK42199.1 - 1.8e-78 263.2 0.0 2.2e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KKK42199.1 - 0.00024 20.4 0.0 0.00052 19.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ATP_bind_1 PF03029.17 KKK42199.1 - 0.002 18.0 0.2 0.0057 16.5 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KKK42199.1 - 0.0025 18.1 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KKK42199.1 - 0.0025 17.7 1.3 0.0063 16.4 0.2 2.1 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 KKK42199.1 - 0.0033 18.0 1.1 0.0068 16.9 0.2 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KKK42199.1 - 0.0071 16.0 0.0 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.19 KKK42199.1 - 0.008 15.8 0.3 1.2 8.7 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KKK42199.1 - 0.0084 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ParA PF10609.9 KKK42199.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase KTI12 PF08433.10 KKK42199.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KKK42199.1 - 0.083 13.3 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 RNA helicase CbiA PF01656.23 KKK42199.1 - 0.087 12.9 0.2 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 KKK42199.1 - 0.1 12.4 0.2 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF1492 PF07374.11 KKK42199.1 - 0.11 12.7 3.8 0.53 10.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) ABC_tran PF00005.27 KKK42199.1 - 0.16 12.5 0.2 0.5 10.9 0.1 1.9 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 KKK42199.1 - 0.17 12.2 0.1 0.34 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Cullin_Nedd8 PF10557.9 KKK42199.1 - 2.3 8.3 6.4 0.93 9.6 2.5 2.2 2 0 0 2 2 2 0 Cullin protein neddylation domain Nitroreductase PF00881.24 KKK42200.1 - 4.1e-20 72.5 0.0 5.3e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK42200.1 - 7.4e-07 29.0 0.3 0.0024 17.5 0.0 2.2 1 1 1 2 2 2 2 Putative TM nitroreductase Fer4_9 PF13187.6 KKK42200.1 - 1.9e-05 24.8 9.7 4.2e-05 23.6 9.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK42200.1 - 2.2e-05 24.1 12.2 0.0022 17.7 2.3 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK42200.1 - 0.0015 19.1 7.7 0.14 12.8 0.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK42200.1 - 0.0029 18.3 9.9 0.045 14.5 1.2 2.6 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_10 PF13237.6 KKK42200.1 - 0.0059 16.7 11.1 0.016 15.3 11.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK42200.1 - 0.037 14.1 12.2 0.28 11.4 2.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KKK42200.1 - 0.039 14.0 12.7 0.16 12.1 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.6 KKK42200.1 - 0.045 14.7 7.0 0.31 12.0 0.6 2.6 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK42200.1 - 0.12 12.9 10.3 1.8 9.1 0.7 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK42200.1 - 0.25 11.9 13.0 2.8 8.6 13.0 2.2 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_21 PF14697.6 KKK42200.1 - 0.31 11.2 10.5 1.6 9.0 10.9 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK42200.1 - 1.5 9.4 15.3 69 4.1 4.4 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK42200.1 - 8.6 7.1 13.1 18 6.1 2.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain RNA_POL_M_15KD PF02150.16 KKK42201.1 - 0.0003 20.6 11.8 0.0007 19.4 0.5 3.9 4 0 0 4 4 4 2 RNA polymerases M/15 Kd subunit DUF562 PF04763.12 KKK42201.1 - 0.056 12.9 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF562) DZR PF12773.7 KKK42201.1 - 0.19 11.8 4.3 0.7 10.0 0.9 2.4 2 1 0 2 2 2 0 Double zinc ribbon RecR PF02132.15 KKK42201.1 - 2.1 8.0 12.5 0.79 9.3 0.6 3.5 4 1 1 5 5 5 0 RecR protein ICMT PF04140.14 KKK42202.1 - 5.2e-05 23.6 1.0 0.00012 22.4 1.0 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KKK42202.1 - 0.0031 17.9 5.3 0.0054 17.1 0.7 2.9 2 1 1 3 3 3 1 Phospholipid methyltransferase CD20 PF04103.15 KKK42202.1 - 0.12 12.4 5.5 0.036 14.1 1.5 2.0 1 1 1 2 2 2 0 CD20-like family HTH_24 PF13412.6 KKK42203.1 - 1.8e-15 56.2 7.0 7.7e-09 35.0 0.8 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KKK42203.1 - 3.1e-09 36.7 0.0 8.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_5 PF01022.20 KKK42203.1 - 4.6e-06 26.4 1.1 0.0064 16.3 0.2 2.4 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KKK42203.1 - 1.6e-05 24.6 0.0 0.0004 20.2 0.0 2.2 2 0 0 2 2 2 1 MarR family MarR PF01047.22 KKK42203.1 - 3.2e-05 23.8 1.3 5.1e-05 23.1 0.3 1.9 2 0 0 2 2 2 1 MarR family RPA_C PF08784.11 KKK42203.1 - 0.00057 20.5 0.5 0.022 15.4 0.0 2.1 2 0 0 2 2 2 1 Replication protein A C terminal Penicillinase_R PF03965.16 KKK42203.1 - 0.00082 19.7 0.5 0.055 13.8 0.1 2.3 1 1 1 2 2 2 1 Penicillinase repressor HTH_11 PF08279.12 KKK42203.1 - 0.0017 18.2 0.8 0.0039 17.1 0.8 1.6 1 0 0 1 1 1 1 HTH domain GerE PF00196.19 KKK42203.1 - 0.0075 15.8 0.4 0.015 14.8 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Rio2_N PF09202.11 KKK42203.1 - 0.0087 16.3 0.5 4.9 7.4 0.1 2.3 2 0 0 2 2 2 2 Rio2, N-terminal TrmB PF01978.19 KKK42203.1 - 0.0092 15.8 0.1 2.7 7.9 0.1 2.5 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.12 KKK42203.1 - 0.016 15.3 2.3 1.1 9.5 0.2 2.3 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC SMC_ScpB PF04079.16 KKK42203.1 - 0.023 14.3 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Rrf2 PF02082.20 KKK42203.1 - 0.027 14.8 0.2 0.05 14.0 0.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_30 PF13556.6 KKK42203.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_Crp_2 PF13545.6 KKK42203.1 - 0.085 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_Mga PF08280.11 KKK42203.1 - 0.13 12.3 3.7 0.16 12.0 1.6 2.2 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Hit1_C PF18268.1 KKK42203.1 - 0.19 11.9 6.1 4.4 7.5 0.1 3.4 2 1 1 3 3 3 0 Hit1 C-terminal URO-D PF01208.17 KKK42204.1 - 5.7e-27 94.8 0.0 1.1e-24 87.2 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) Abhydrolase_1 PF00561.20 KKK42205.1 - 7.9e-15 55.2 0.1 4.4e-13 49.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK42205.1 - 4.6e-09 37.2 0.0 5.3e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK42205.1 - 4.5e-05 22.8 0.0 0.00028 20.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK42205.1 - 0.002 16.9 0.0 0.0078 14.9 0.0 1.9 1 1 0 1 1 1 1 Ndr family Tom5 PF10642.9 KKK42205.1 - 0.17 11.9 0.4 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Vac14_Fab1_bd PF12755.7 KKK42208.1 - 0.03 14.9 0.7 53 4.5 0.0 4.4 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region DUF3658 PF12395.8 KKK42208.1 - 0.047 13.6 0.0 13 5.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function Prolactin_RP PF15172.6 KKK42208.1 - 1.3 8.7 14.8 16 5.2 0.1 6.1 6 0 0 6 6 6 0 Prolactin-releasing peptide PA14 PF07691.12 KKK42208.1 - 2.8 7.8 5.6 7.7 6.3 0.1 4.2 5 0 0 5 5 5 0 PA14 domain Abhydrolase_1 PF00561.20 KKK42209.1 - 4.8e-25 88.7 0.0 3.6e-23 82.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK42209.1 - 2.2e-16 59.9 0.0 1.8e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK42209.1 - 9.6e-12 46.0 0.0 1.2e-11 45.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KKK42209.1 - 3e-07 30.0 0.4 0.016 14.6 0.0 3.0 4 0 0 4 4 4 2 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 KKK42209.1 - 5e-07 28.7 0.0 7.2e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 KKK42209.1 - 0.0025 17.7 0.3 0.78 9.5 0.0 2.8 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KKK42209.1 - 0.0053 16.5 1.7 3.7 7.1 0.5 3.0 1 1 0 2 2 2 2 Serine hydrolase (FSH1) PGAP1 PF07819.13 KKK42209.1 - 0.0084 15.9 0.1 0.37 10.5 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 KKK42209.1 - 0.011 15.5 0.0 0.013 15.4 0.0 1.3 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_4 PF08386.10 KKK42209.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein UPF0227 PF05728.12 KKK42209.1 - 0.017 15.1 0.0 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 KKK42209.1 - 0.032 14.0 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KKK42209.1 - 0.089 12.3 0.0 1.4 8.3 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KKK42210.1 - 3.8e-28 98.8 0.0 2.1e-27 96.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK42210.1 - 2.8e-12 46.4 0.0 1e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK42210.1 - 1.6e-11 45.2 0.0 1.9e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KKK42210.1 - 2.6e-07 29.7 0.0 6.7e-07 28.3 0.0 1.6 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.10 KKK42210.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 KKK42210.1 - 0.00019 21.0 0.0 0.0042 16.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KKK42210.1 - 0.00058 19.7 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family BAAT_C PF08840.11 KKK42210.1 - 0.018 15.0 0.1 0.098 12.6 0.1 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 KKK42210.1 - 0.041 13.8 0.1 6.8 6.6 0.0 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 KKK42210.1 - 0.058 13.2 0.0 0.43 10.4 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KKK42211.1 - 4.4e-25 88.4 7.7 4.8e-25 88.2 7.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK42211.1 - 8.2e-11 41.4 2.4 8.6e-11 41.3 2.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KKK42211.1 - 0.00019 20.4 0.6 0.0002 20.3 0.6 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_5 PF05631.14 KKK42211.1 - 0.018 14.0 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM MFS_3 PF05977.13 KKK42211.1 - 0.068 11.5 0.0 0.082 11.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Ribosomal_S27e PF01667.17 KKK42218.1 - 1e-06 28.4 0.1 1.3e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 Ribosomal_L44 PF00935.19 KKK42219.1 - 9.2e-25 86.9 6.4 9.2e-25 86.9 6.4 1.4 1 1 1 2 2 2 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 KKK42219.1 - 0.0037 17.7 13.0 0.005 17.2 1.4 3.0 3 0 0 3 3 3 2 Ribosomal protein L33 RNA_POL_M_15KD PF02150.16 KKK42219.1 - 0.083 12.8 1.4 3.1 7.8 0.0 2.4 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.6 KKK42219.1 - 0.58 9.9 5.1 1.9 8.3 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain OTCace_N PF02729.21 KKK42220.1 - 1.6e-46 158.0 0.0 3e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KKK42220.1 - 9.6e-26 90.7 0.0 1.4e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3251 PF11622.8 KKK42220.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) NRDD PF13597.6 KKK42221.1 - 3.5e-16 59.1 1.7 3.6e-14 52.5 1.4 2.2 2 0 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_45 PF14947.6 KKK42221.1 - 0.00013 21.9 1.1 0.00064 19.7 1.1 2.2 1 0 0 1 1 1 1 Winged helix-turn-helix PARP_reg PF02877.14 KKK42221.1 - 0.043 13.9 1.0 0.12 12.4 0.3 2.3 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain HTH_20 PF12840.7 KKK42221.1 - 0.071 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 KKK42221.1 - 0.13 12.1 0.3 0.65 9.9 0.3 2.1 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family MTS PF05175.14 KKK42222.1 - 3.6e-30 104.7 0.0 5.8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KKK42222.1 - 0.00039 20.2 0.5 0.00071 19.4 0.1 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_15 PF09445.10 KKK42222.1 - 0.00065 19.3 0.4 0.0027 17.3 0.0 2.1 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KKK42222.1 - 0.0077 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KKK42222.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_31 PF13847.6 KKK42222.1 - 0.099 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nitroreductase PF00881.24 KKK42223.1 - 4.4e-05 23.6 0.6 0.13 12.3 0.1 3.1 2 2 0 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 KKK42223.1 - 0.003 17.1 0.1 0.019 14.6 0.0 2.2 2 0 0 2 2 2 1 Putative TM nitroreductase Ribosomal_S7 PF00177.21 KKK42224.1 - 4.9e-31 107.4 0.2 6.4e-31 107.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 KKK42225.1 - 1.1e-47 160.3 0.9 1.4e-47 160.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Peptidase_M28 PF04389.17 KKK42226.1 - 1.5e-21 77.0 0.0 7.4e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 Peptidase_M42 PF05343.14 KKK42226.1 - 8e-06 25.1 0.0 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KKK42226.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 MgtE PF01769.16 KKK42226.1 - 0.51 10.7 8.1 1.7 9.0 1.5 2.3 2 0 0 2 2 2 0 Divalent cation transporter KH_2 PF07650.17 KKK42227.1 - 6.4e-14 51.5 9.0 1.7e-07 31.0 3.5 2.4 2 1 0 2 2 2 2 KH domain KH_5 PF13184.6 KKK42227.1 - 8.6e-14 51.4 6.4 2.6e-11 43.4 1.2 2.3 2 0 0 2 2 2 2 NusA-like KH domain KH_4 PF13083.6 KKK42227.1 - 9.9e-11 41.4 2.1 1.1e-05 25.2 0.5 2.3 2 0 0 2 2 2 2 KH domain KH_1 PF00013.29 KKK42227.1 - 5.1e-06 26.2 7.5 0.0097 15.7 1.5 2.8 1 1 1 2 2 2 2 KH domain Ribosomal_L7Ae PF01248.26 KKK42228.1 - 1.1e-12 47.4 0.0 1.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNA_pol_Rpb1_5 PF04998.17 KKK42229.1 - 9.5e-52 176.1 0.6 1.4e-51 175.5 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KKK42230.1 - 1e-96 324.0 0.2 1.9e-96 323.1 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KKK42230.1 - 6e-71 238.0 0.0 1.4e-70 236.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KKK42230.1 - 5.5e-30 104.4 0.0 1.3e-29 103.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.17 KKK42230.1 - 1.4e-28 100.1 0.0 2.6e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 KKK42230.1 - 4.8e-26 90.8 0.0 1.3e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 MPS2 PF17060.5 KKK42230.1 - 0.054 12.8 0.7 0.092 12.0 0.7 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 FGGY_N PF00370.21 KKK42237.1 - 3e-36 125.2 0.2 1.3e-34 119.8 0.2 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DAO PF01266.24 KKK42238.1 - 5.7e-53 180.7 0.0 3.3e-52 178.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 KKK42238.1 - 5.5e-23 81.2 0.0 1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KKK42238.1 - 9.8e-06 24.9 1.4 0.00028 20.1 1.4 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KKK42238.1 - 0.0014 18.0 1.0 0.014 14.7 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK42238.1 - 0.0031 16.8 1.4 0.011 15.0 1.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK42238.1 - 0.0064 16.7 1.7 0.015 15.5 1.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKK42238.1 - 0.013 14.7 0.2 0.021 14.1 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KKK42238.1 - 0.014 15.3 0.3 0.035 14.0 0.3 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 KKK42238.1 - 0.015 14.7 0.3 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.12 KKK42238.1 - 0.042 12.9 2.3 0.32 10.0 0.6 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein DnaG_DnaB_bind PF08278.11 KKK42238.1 - 0.049 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Pyr_redox PF00070.27 KKK42238.1 - 0.13 12.8 1.1 0.42 11.2 1.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PFL-like PF02901.15 KKK42239.1 - 1.3e-167 559.3 0.0 1.7e-167 558.9 0.0 1.0 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 KKK42239.1 - 4e-26 91.6 0.0 1.3e-25 90.0 0.0 1.9 2 0 0 2 2 2 1 Glycine radical RHH_1 PF01402.21 KKK42240.1 - 0.00055 19.8 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family gag-asp_proteas PF13975.6 KKK42240.1 - 0.009 16.6 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKK42240.1 - 0.0095 16.6 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 KKK42240.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Spuma_A9PTase PF03539.14 KKK42240.1 - 0.018 15.2 1.5 0.025 14.7 0.1 1.8 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) Band_7 PF01145.25 KKK42247.1 - 9.1e-27 94.2 0.2 9.1e-27 94.2 0.2 2.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family Adeno_E3_CR2 PF02439.15 KKK42247.1 - 0.017 14.8 0.3 0.039 13.7 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FtsH_ext PF06480.15 KKK42247.1 - 0.049 14.0 0.2 0.085 13.2 0.2 1.4 1 0 0 1 1 1 0 FtsH Extracellular Flot PF15975.5 KKK42247.1 - 0.15 12.3 21.5 0.1 12.8 2.7 3.5 2 1 1 3 3 3 0 Flotillin DUF1449 PF07290.11 KKK42248.1 - 6.3e-05 22.7 4.7 0.0058 16.3 4.7 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1449) Bactofilin PF04519.13 KKK42248.1 - 0.0043 17.3 0.7 0.0072 16.6 0.7 1.3 1 0 0 1 1 1 1 Polymer-forming cytoskeletal NfeD PF01957.18 KKK42248.1 - 0.0084 16.5 1.3 0.098 13.0 0.0 2.7 3 1 0 3 3 3 1 NfeD-like C-terminal, partner-binding DUF1943 PF09172.11 KKK42248.1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) NESP55 PF06390.12 KKK42248.1 - 3 7.4 4.6 21 4.6 4.6 1.9 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DUF3194 PF11419.8 KKK42248.1 - 7.5 7.0 23.9 8.1 6.9 0.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3194) zinc_ribbon_2 PF13240.6 KKK42249.1 - 2e-06 27.3 2.2 3.2e-06 26.7 2.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK42249.1 - 2.1e-05 24.5 0.4 3.4e-05 23.8 0.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK42249.1 - 5.1e-05 22.5 0.5 0.0001 21.6 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK42249.1 - 0.00015 22.5 1.3 0.00015 22.5 1.3 1.9 2 1 0 2 2 2 1 zinc-ribbon family Tetraspanin PF00335.20 KKK42249.1 - 0.0032 17.2 0.1 0.0039 17.0 0.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 KKK42249.1 - 0.0054 16.8 0.5 0.0074 16.3 0.5 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Nudix_N_2 PF14803.6 KKK42249.1 - 0.013 15.4 4.1 0.92 9.5 0.8 2.3 2 0 0 2 2 2 0 Nudix N-terminal Cript PF10235.9 KKK42249.1 - 0.015 15.8 0.7 0.027 15.0 0.7 1.5 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT DUF2207 PF09972.9 KKK42249.1 - 0.057 12.2 4.1 0.074 11.8 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 KKK42249.1 - 0.24 12.3 0.8 8 7.4 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UPF0547 PF10571.9 KKK42249.1 - 0.68 10.1 5.2 4.3 7.5 4.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 Baculo_11_kDa PF06143.11 KKK42249.1 - 0.91 9.1 7.4 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family TPR_1 PF00515.28 KKK42251.1 - 7e-16 57.3 9.8 0.00029 20.5 0.0 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK42251.1 - 7.4e-15 53.8 2.0 0.015 15.4 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 KKK42251.1 - 1.9e-13 50.7 0.0 0.00023 21.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK42251.1 - 2.8e-09 37.1 0.0 1.8e-05 25.0 0.0 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KKK42251.1 - 1.1e-08 34.6 16.1 0.00073 19.6 0.0 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat HTH_45 PF14947.6 KKK42251.1 - 2.9e-08 33.6 1.5 0.0047 16.9 0.0 3.1 2 0 0 2 2 2 2 Winged helix-turn-helix TPR_14 PF13428.6 KKK42251.1 - 7e-08 32.7 0.0 1.2 10.1 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK42251.1 - 1.1e-07 32.4 0.0 0.0072 17.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK42251.1 - 1.9e-07 31.2 1.6 0.61 10.3 0.1 5.8 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KKK42251.1 - 3.5e-07 30.4 1.3 14 6.5 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat HTH_34 PF13601.6 KKK42251.1 - 1e-06 28.8 0.0 0.073 13.3 0.0 2.9 2 0 0 2 2 2 2 Winged helix DNA-binding domain TPR_11 PF13414.6 KKK42251.1 - 6.9e-06 25.6 1.1 0.0031 17.2 0.0 3.6 3 0 0 3 3 3 1 TPR repeat NARP1 PF12569.8 KKK42251.1 - 1.8e-05 23.9 8.1 0.023 13.6 0.3 4.1 2 1 2 4 4 4 3 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 KKK42251.1 - 1.9e-05 24.7 0.1 0.41 11.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Mrr_N PF14338.6 KKK42251.1 - 5.3e-05 23.3 0.0 0.041 14.0 0.0 3.0 2 0 0 2 2 2 1 Mrr N-terminal domain TPR_7 PF13176.6 KKK42251.1 - 0.00015 21.6 0.1 0.45 10.7 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KKK42251.1 - 0.0018 18.3 17.8 0.25 11.4 0.9 4.7 3 1 1 4 4 4 3 Putative TPR-like repeat HTH_5 PF01022.20 KKK42251.1 - 0.0056 16.5 0.5 0.83 9.6 0.0 3.2 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family TPR_10 PF13374.6 KKK42251.1 - 0.024 14.5 0.4 9.2 6.3 0.0 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat ATP13 PF12921.7 KKK42251.1 - 0.027 14.3 7.7 0.65 9.9 1.2 3.2 3 0 0 3 3 2 0 Mitochondrial ATPase expression MarR PF01047.22 KKK42251.1 - 0.031 14.2 0.0 11 6.1 0.0 2.9 3 0 0 3 3 3 0 MarR family PadR PF03551.14 KKK42251.1 - 0.078 13.0 0.1 5.1 7.1 0.0 2.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family RPN6_C_helix PF18503.1 KKK42251.1 - 0.14 12.0 0.9 20 5.0 0.2 3.6 3 0 0 3 3 3 0 26S proteasome subunit RPN6 C-terminal helix domain DUF3795 PF12675.7 KKK42253.1 - 4.4e-10 39.8 19.8 1e-08 35.5 16.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3795) Sybindin PF04099.12 KKK42254.1 - 0.0028 17.6 0.7 0.0055 16.6 0.2 1.8 2 0 0 2 2 2 1 Sybindin-like family Syndecan PF01034.20 KKK42254.1 - 0.039 13.9 0.7 0.039 13.9 0.7 3.1 3 0 0 3 3 3 0 Syndecan domain FliG_M PF14841.6 KKK42254.1 - 0.13 12.5 0.1 2 8.7 0.0 2.7 3 0 0 3 3 3 0 FliG middle domain DUF1129 PF06570.11 KKK42254.1 - 3.7 7.0 11.3 0.33 10.4 4.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) 3HCDH_N PF02737.18 KKK42255.1 - 5.1e-45 153.6 0.0 8.3e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK42255.1 - 1.6e-19 70.3 0.1 3e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK42255.1 - 0.00027 21.1 0.0 0.0013 18.9 0.0 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KKK42255.1 - 0.002 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KKK42255.1 - 0.0048 17.4 1.5 0.18 12.4 1.5 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PIN_2 PF10130.9 KKK42255.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 PIN domain ApbA PF02558.16 KKK42255.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Peptidase_U32 PF01136.19 KKK42256.1 - 1.6e-80 269.6 0.1 2.1e-80 269.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family U32 Glyco_hydro38C2 PF17677.1 KKK42256.1 - 0.11 12.6 0.4 0.5 10.5 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain adh_short PF00106.25 KKK42258.1 - 1.6e-38 132.1 0.3 2.2e-38 131.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK42258.1 - 8.1e-25 87.7 0.0 1.1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK42258.1 - 6.8e-12 45.6 0.1 9.2e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK42258.1 - 0.0018 17.8 0.1 0.0027 17.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK42258.1 - 0.032 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 KKK42258.1 - 0.054 13.4 0.8 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 KKK42258.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 KKK42258.1 - 0.068 12.5 0.1 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Phage_P2_GpE PF06528.12 KKK42258.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpE Ras PF00071.22 KKK42259.1 - 1.5e-47 161.3 0.2 1.9e-47 160.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42259.1 - 1.9e-30 105.5 0.1 4.1e-30 104.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42259.1 - 2e-15 56.7 0.1 3e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42259.1 - 2e-07 30.6 0.1 2.6e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK42259.1 - 2.2e-07 30.9 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK42259.1 - 2.4e-07 30.5 0.1 7.5e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK42259.1 - 0.00014 21.3 0.1 0.00041 19.8 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KKK42259.1 - 0.00022 21.1 0.0 0.0035 17.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KKK42259.1 - 0.0011 18.2 1.7 0.033 13.3 0.7 2.9 1 1 1 2 2 2 1 G-protein alpha subunit AAA PF00004.29 KKK42259.1 - 0.0026 18.2 0.3 0.064 13.7 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KKK42259.1 - 0.0072 15.9 0.5 0.67 9.5 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_14 PF13173.6 KKK42259.1 - 0.0092 16.0 0.3 0.077 13.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK42259.1 - 0.013 15.9 0.0 0.022 15.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KKK42259.1 - 0.014 15.7 0.0 0.056 13.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain TFIID-18kDa PF02269.16 KKK42259.1 - 0.023 14.7 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit AAA_18 PF13238.6 KKK42259.1 - 0.055 14.0 0.1 0.22 12.1 0.0 2.1 2 2 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KKK42259.1 - 0.075 12.8 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 KKK42259.1 - 0.1 12.0 0.1 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAR2 PF05282.11 KKK42260.1 - 6.6e-24 85.0 2.3 8.2e-12 45.2 0.1 2.0 1 1 1 2 2 2 2 AAR2 protein Cas_NE0113 PF09623.10 KKK42261.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) FAD-oxidase_C PF02913.19 KKK42262.1 - 3.5e-32 112.0 0.0 5e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KKK42262.1 - 4.9e-21 74.9 0.0 3.7e-09 36.5 0.1 2.3 1 1 1 2 2 2 2 FAD binding domain AFOR_C PF01314.18 KKK42263.1 - 2.1e-94 316.7 0.0 3e-94 316.2 0.0 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK42263.1 - 2.7e-64 216.7 0.1 3.9e-64 216.2 0.1 1.3 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain HATPase_c PF02518.26 KKK42265.1 - 2.1e-05 25.0 0.0 2.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK42265.1 - 0.0049 16.7 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 GHKL domain Actin PF00022.19 KKK42269.1 - 6.5e-134 446.6 0.0 1.7e-133 445.2 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKK42269.1 - 2.9e-06 26.3 0.0 3.6e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein LRR_4 PF12799.7 KKK42270.1 - 1.6e-32 111.0 84.4 3.9e-07 30.3 10.6 8.3 7 1 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK42270.1 - 1.7e-23 82.2 112.6 2.3e-06 27.3 9.8 7.6 3 1 6 10 10 10 8 Leucine rich repeat LRR_9 PF14580.6 KKK42270.1 - 1.7e-17 63.5 41.3 7e-06 25.7 8.1 4.9 1 1 4 5 5 5 5 Leucine-rich repeat HEAT_2 PF13646.6 KKK42270.1 - 0.019 15.3 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 HEAT repeats Acetyltransf_1 PF00583.25 KKK42271.1 - 7.6e-12 45.5 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK42271.1 - 9.2e-12 45.0 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK42271.1 - 2.9e-09 37.7 0.0 3.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK42271.1 - 3.7e-09 36.9 0.0 6.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK42271.1 - 3.5e-08 33.7 0.8 6e-08 33.0 0.8 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK42271.1 - 0.00019 21.3 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Pho86 PF11124.8 KKK42271.1 - 0.018 14.5 0.3 0.026 14.0 0.0 1.4 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Acetyltransf_9 PF13527.7 KKK42271.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2684 PF10885.8 KKK42271.1 - 0.14 12.3 0.8 3.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2684) Acetyltransf_8 PF13523.6 KKK42271.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_pol_B PF00136.21 KKK42279.1 - 2.9e-27 95.5 0.1 4.6e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KKK42279.1 - 1.1e-11 44.5 5.4 1.1e-11 44.5 5.4 2.8 2 2 1 3 3 3 1 DNA polymerase family B, exonuclease domain PIG-L PF02585.17 KKK42279.1 - 0.069 13.8 0.0 15 6.2 0.0 2.7 3 0 0 3 3 3 0 GlcNAc-PI de-N-acetylase VAR1 PF05316.12 KKK42280.1 - 0.017 14.2 0.3 0.019 14.0 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) Pox_VLTF3 PF04947.14 KKK42282.1 - 0.027 14.2 0.6 0.031 14.0 0.6 1.1 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Terminase_2 PF03592.16 KKK42282.1 - 0.11 13.0 0.0 0.11 12.9 0.0 1.0 1 0 0 1 1 1 0 Terminase small subunit DUF1279 PF06916.13 KKK42282.1 - 0.12 13.0 0.0 0.16 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) N6_Mtase PF02384.16 KKK42284.1 - 1.1e-13 51.1 0.2 2.8e-08 33.4 0.0 3.0 3 0 0 3 3 3 2 N-6 DNA Methylase UPF0020 PF01170.18 KKK42284.1 - 2.7e-06 27.2 0.0 0.0074 16.0 0.0 2.5 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 MTS PF05175.14 KKK42284.1 - 0.071 12.7 0.0 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KKK42284.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ndufs5 PF10200.9 KKK42286.1 - 0.049 13.9 0.4 0.054 13.8 0.4 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF1690 PF07956.11 KKK42287.1 - 0.036 14.5 0.7 0.049 14.1 0.7 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DNA_RNApol_7kD PF03604.13 KKK42288.1 - 0.16 11.7 0.4 0.4 10.4 0.1 1.8 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit YcxB PF14317.6 KKK42289.1 - 0.019 14.6 0.1 0.046 13.4 0.0 1.6 1 1 1 2 2 2 0 YcxB-like protein NosD PF05048.13 KKK42290.1 - 7.4e-75 251.3 153.0 2.2e-31 109.0 31.1 5.7 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK42290.1 - 2.7e-55 186.6 168.3 3.8e-18 65.8 26.9 7.0 2 1 4 7 7 7 6 Right handed beta helix region HTH_45 PF14947.6 KKK42291.1 - 7.9e-12 45.0 0.7 1e-11 44.6 0.7 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 KKK42291.1 - 0.017 14.9 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) zinc_ribbon_15 PF17032.5 KKK42292.1 - 0.0045 17.7 0.7 0.0099 16.6 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK42292.1 - 0.0078 15.6 2.9 0.012 15.0 2.9 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK42292.1 - 0.013 15.5 0.6 0.02 14.9 0.6 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK42292.1 - 0.3 10.8 8.3 0.8 9.5 8.3 1.7 1 1 0 1 1 1 0 zinc-ribbon domain DUF2207 PF09972.9 KKK42292.1 - 0.56 8.9 8.8 1.5 7.4 3.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3792 PF12670.7 KKK42293.1 - 0.13 12.4 10.5 0.2 11.8 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Gram_pos_anchor PF00746.21 KKK42294.1 - 0.78 9.7 2.6 1.6 8.7 2.6 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif MarR PF01047.22 KKK42296.1 - 0.00085 19.2 0.4 0.0014 18.5 0.3 1.5 1 1 0 1 1 1 1 MarR family HxlR PF01638.17 KKK42296.1 - 0.0029 17.4 0.8 0.0036 17.1 0.7 1.3 1 1 0 1 1 1 1 HxlR-like helix-turn-helix TrmB PF01978.19 KKK42296.1 - 0.0047 16.8 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 KKK42296.1 - 0.0057 16.5 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 KKK42296.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_34 PF13601.6 KKK42296.1 - 0.011 15.9 0.4 0.014 15.6 0.4 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain MS_channel PF00924.18 KKK42297.1 - 4e-21 75.5 3.3 4e-21 75.5 3.3 1.6 2 1 0 2 2 2 1 Mechanosensitive ion channel MS_channel PF00924.18 KKK42298.1 - 1.4e-19 70.5 4.0 1.4e-19 70.5 4.0 2.2 2 0 0 2 2 2 2 Mechanosensitive ion channel ARL2_Bind_BART PF11527.8 KKK42298.1 - 0.00013 22.1 0.3 0.00029 20.9 0.3 1.6 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART LRR_4 PF12799.7 KKK42299.1 - 9e-07 29.1 6.2 0.004 17.5 0.8 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK42299.1 - 0.00042 20.0 1.6 0.011 15.5 0.1 2.3 1 1 1 2 2 2 2 Leucine rich repeat NKWYS PF10364.9 KKK42299.1 - 0.021 15.0 0.3 4 7.6 0.3 2.3 1 1 1 2 2 2 0 Putative capsular polysaccharide synthesis protein LRR_1 PF00560.33 KKK42299.1 - 3 8.8 4.5 75 4.5 0.1 3.4 3 1 0 3 3 3 0 Leucine Rich Repeat UCR_Fe-S_N PF10399.9 KKK42300.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF4131 PF13567.6 KKK42300.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) GyrI-like PF06445.15 KKK42302.1 - 2.4e-22 79.9 0.1 3.1e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Ins134_P3_kin_N PF17927.1 KKK42302.1 - 0.14 12.6 0.4 1.3 9.5 0.1 2.6 3 0 0 3 3 3 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ERAP1_C PF11838.8 KKK42303.1 - 0.14 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain BssC_TutF PF08201.11 KKK42304.1 - 0.0038 17.2 2.0 0.0038 17.2 2.0 1.7 1 1 1 2 2 2 1 BssC/TutF protein TrmB PF01978.19 KKK42305.1 - 2.6e-10 40.0 2.2 6.3e-09 35.6 0.1 2.9 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 KKK42305.1 - 9e-06 25.2 9.2 0.0036 16.8 2.3 3.6 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding Regulator_TrmB PF11495.8 KKK42305.1 - 0.00015 21.1 0.1 0.00025 20.3 0.1 1.4 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB FaeA PF04703.12 KKK42305.1 - 0.0003 21.1 2.1 0.063 13.7 0.1 3.1 3 0 0 3 3 3 2 FaeA-like protein HTH_9 PF08221.11 KKK42305.1 - 0.00067 19.7 0.3 0.066 13.3 0.1 2.7 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_45 PF14947.6 KKK42305.1 - 0.032 14.2 11.0 0.28 11.2 0.4 4.0 4 1 0 4 4 4 0 Winged helix-turn-helix HTH_34 PF13601.6 KKK42305.1 - 0.14 12.4 2.8 1.6 9.0 0.3 2.8 2 1 0 2 2 2 0 Winged helix DNA-binding domain DpnII PF04556.12 KKK42307.1 - 0.054 12.8 1.2 0.059 12.7 1.2 1.1 1 0 0 1 1 1 0 DpnII restriction endonuclease DXP_reductoisom PF02670.16 KKK42307.1 - 0.17 12.6 0.0 0.23 12.2 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SH2_2 PF14633.6 KKK42308.1 - 0.063 12.7 0.7 0.16 11.3 0.1 2.0 2 0 0 2 2 2 0 SH2 domain MFS_1 PF07690.16 KKK42309.1 - 8.1e-62 209.2 61.8 5.7e-51 173.5 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK42309.1 - 3.1e-17 62.6 32.0 1.2e-16 60.7 8.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 KKK42309.1 - 5.7e-11 41.6 28.1 5.7e-11 41.6 28.1 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 KKK42309.1 - 9.6e-10 37.9 39.3 1.5e-06 27.3 1.9 3.4 1 1 2 3 3 3 3 MFS_1 like family Folate_carrier PF01770.18 KKK42309.1 - 0.00044 19.1 11.4 0.00063 18.6 0.1 2.2 2 0 0 2 2 2 1 Reduced folate carrier MFS_3 PF05977.13 KKK42309.1 - 0.0076 14.7 17.4 0.038 12.4 10.3 2.8 1 1 2 3 3 3 3 Transmembrane secretion effector DUF3397 PF11877.8 KKK42310.1 - 0.93 9.7 7.3 2.3 8.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) AP_endonuc_2 PF01261.24 KKK42311.1 - 3e-17 62.8 0.0 8.8e-17 61.2 0.0 1.7 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel Fe_dep_repr_C PF02742.15 KKK42320.1 - 0.0096 16.0 0.1 0.38 10.9 0.1 2.0 1 1 1 2 2 2 2 Iron dependent repressor, metal binding and dimerisation domain Bactofilin PF04519.13 KKK42322.1 - 1.1e-06 28.9 15.6 0.01 16.1 1.8 3.5 1 1 1 2 2 2 2 Polymer-forming cytoskeletal ApoLp-III PF07464.11 KKK42323.1 - 0.00019 21.5 7.8 0.00019 21.5 7.8 2.8 2 1 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 KKK42323.1 - 0.00065 19.6 17.4 0.0028 17.6 14.6 2.4 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 KKK42323.1 - 0.0011 17.1 3.9 0.0016 16.5 3.9 1.3 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.12 KKK42323.1 - 0.0013 18.8 0.4 0.014 15.4 0.0 2.5 2 1 1 3 3 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2884 PF11101.8 KKK42323.1 - 0.0015 18.1 8.6 0.0015 18.1 8.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2884) DUF883 PF05957.13 KKK42323.1 - 0.0059 17.2 11.0 1.4 9.6 5.1 3.3 1 1 1 3 3 2 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 KKK42323.1 - 0.011 16.3 1.8 0.011 16.3 1.8 4.7 3 1 1 4 4 4 0 YtxH-like protein PCI PF01399.27 KKK42323.1 - 0.013 16.0 1.1 0.093 13.3 0.0 2.6 1 1 1 2 2 2 0 PCI domain SH3BP5 PF05276.14 KKK42323.1 - 0.014 15.3 2.8 0.014 15.3 2.8 2.8 2 1 1 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) BBP1_C PF15272.6 KKK42323.1 - 0.041 13.7 19.2 0.13 12.1 16.2 2.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal YojJ PF10372.9 KKK42323.1 - 0.066 13.3 1.2 0.066 13.3 1.2 3.2 2 1 1 3 3 2 0 Bacterial membrane-spanning protein N-terminus Cob_adeno_trans PF01923.18 KKK42323.1 - 0.084 13.0 5.2 0.13 12.4 3.6 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase 5_nucleotid PF05761.14 KKK42323.1 - 0.1 11.5 3.5 0.15 10.9 3.4 1.4 1 1 0 1 1 1 0 5' nucleotidase family SIR4_SID PF16991.5 KKK42323.1 - 0.17 11.9 10.9 0.093 12.8 5.5 2.4 2 0 0 2 2 2 0 Sir4 SID domain DUF4407 PF14362.6 KKK42323.1 - 0.24 10.7 7.8 0.33 10.3 7.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 KKK42323.1 - 0.24 10.8 21.3 0.18 11.2 6.7 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 ApoO PF09769.9 KKK42323.1 - 0.24 11.3 0.4 7.6 6.5 0.2 2.5 1 1 1 2 2 2 0 Apolipoprotein O Ribosomal_S6 PF01250.17 KKK42323.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.9 3 1 0 3 3 2 0 Ribosomal protein S6 SseC PF04888.12 KKK42323.1 - 0.34 10.5 11.8 0.07 12.7 4.5 2.7 1 1 2 3 3 3 0 Secretion system effector C (SseC) like family GyrB_insert PF18053.1 KKK42323.1 - 0.36 10.7 5.9 0.72 9.7 2.9 2.4 1 1 0 2 2 2 0 DNA gyrase B subunit insert domain DUF2935 PF11155.8 KKK42323.1 - 0.4 11.0 3.2 0.86 9.9 0.6 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Cor1 PF04803.12 KKK42323.1 - 0.4 10.9 13.9 0.12 12.6 1.5 3.1 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region Ndc1_Nup PF09531.10 KKK42323.1 - 0.47 9.1 4.2 0.66 8.6 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Exonuc_VII_L PF02601.15 KKK42323.1 - 0.57 9.7 9.3 2.3 7.7 9.3 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 KKK42323.1 - 0.71 10.5 19.6 2.5 8.8 4.2 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Gp-FAR-1 PF05823.12 KKK42323.1 - 1.1 9.6 15.6 5 7.5 10.3 3.4 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4085 PF13315.6 KKK42323.1 - 1.3 8.6 18.1 5.8 6.5 16.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) Atg14 PF10186.9 KKK42323.1 - 1.4 7.9 15.8 0.41 9.7 12.3 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 KKK42323.1 - 1.6 9.1 14.8 0.24 11.7 5.0 3.4 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2205 PF10224.9 KKK42323.1 - 1.7 8.7 10.3 0.7 9.9 4.3 2.9 1 1 1 2 2 2 0 Short coiled-coil protein Spc7 PF08317.11 KKK42323.1 - 2 7.2 25.8 2.7 6.8 21.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 KKK42323.1 - 2.3 8.6 11.1 0.86 9.9 0.2 3.2 2 1 1 3 3 2 0 Uncharacterized conserved protein DUF1640 PF07798.11 KKK42323.1 - 2.9 7.9 22.1 5.7 6.9 19.3 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) BST2 PF16716.5 KKK42323.1 - 3.3 8.4 13.6 0.7 10.5 7.6 3.0 1 1 1 3 3 2 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 KKK42323.1 - 3.8 7.6 13.9 3.5 7.7 5.4 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 KKK42323.1 - 3.9 7.9 18.3 0.054 13.9 4.8 3.5 3 1 1 4 4 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CdvA PF18822.1 KKK42323.1 - 4.5 7.1 25.0 0.092 12.6 4.3 3.9 3 2 1 4 4 4 0 CdvA-like coiled-coil domain OmpH PF03938.14 KKK42323.1 - 6.5 7.1 22.3 1.8e+02 2.4 0.1 3.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SKA2 PF16740.5 KKK42323.1 - 6.6 6.6 11.3 4.6 7.1 6.7 2.7 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 FAM184 PF15665.5 KKK42323.1 - 6.8 6.4 22.8 1 9.1 12.3 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 KKK42323.1 - 7.5 5.7 14.6 3.8 6.7 8.1 2.6 1 1 2 3 3 3 0 TMPIT-like protein DUF2884 PF11101.8 KKK42324.1 - 0.012 15.1 0.3 0.019 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) RE_MjaI PF09568.10 KKK42324.1 - 0.015 15.1 0.5 0.025 14.4 0.4 1.7 1 1 0 1 1 1 0 MjaI restriction endonuclease DUF977 PF06163.11 KKK42324.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) PCI PF01399.27 KKK42324.1 - 0.052 14.1 0.1 0.089 13.3 0.1 1.4 1 1 0 1 1 1 0 PCI domain Cecropin PF00272.19 KKK42324.1 - 0.19 11.5 2.3 0.72 9.6 0.3 2.4 2 1 0 2 2 2 0 Cecropin family Peptidase_M29 PF02073.15 KKK42325.1 - 1.2e-85 287.7 0.0 1.4e-85 287.6 0.0 1.0 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) MFS_1 PF07690.16 KKK42327.1 - 1.7e-36 125.9 39.8 1.7e-36 125.9 39.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KKK42327.1 - 1.2e-19 70.1 21.1 1.6e-19 69.8 21.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 KKK42327.1 - 0.00022 19.9 41.5 0.002 16.7 13.3 2.8 1 1 2 3 3 3 2 MFS/sugar transport protein DUF4337 PF14235.6 KKK42327.1 - 0.32 11.1 1.6 0.71 10.0 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DZR PF12773.7 KKK42328.1 - 0.00078 19.4 6.6 0.38 10.8 7.1 2.2 1 1 1 2 2 2 2 Double zinc ribbon zf-C3HC4_3 PF13920.6 KKK42328.1 - 0.00079 19.2 9.3 0.0013 18.5 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 KKK42328.1 - 0.0068 16.7 8.2 0.0068 16.7 8.2 2.1 1 1 0 2 2 2 1 C1 domain zf-C4pol PF14260.6 KKK42328.1 - 0.011 16.2 4.7 0.38 11.2 0.8 2.4 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-HIT PF04438.16 KKK42328.1 - 0.038 13.9 9.0 0.038 13.9 9.0 1.9 2 0 0 2 2 2 0 HIT zinc finger zinc_ribbon_15 PF17032.5 KKK42328.1 - 0.08 13.7 0.7 0.08 13.7 0.7 2.9 2 1 1 3 3 3 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK42328.1 - 0.34 10.4 13.1 0.71 9.4 0.5 2.8 1 1 2 3 3 3 0 zinc-ribbon domain IBR PF01485.21 KKK42328.1 - 0.44 10.8 10.9 1.4 9.2 7.8 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain PHF5 PF03660.14 KKK42328.1 - 0.93 9.7 8.4 1.9 8.7 5.0 2.2 1 1 1 2 2 2 0 PHF5-like protein Prok-RING_1 PF14446.6 KKK42328.1 - 3 7.8 11.1 7 6.7 7.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KKK42328.1 - 4.9 7.6 11.9 4.4 7.7 10.6 1.6 2 0 0 2 2 2 0 Ring finger domain ParE_toxin PF05016.15 KKK42329.1 - 2.3e-10 40.9 0.0 2.5e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HSL_N PF06350.12 KKK42329.1 - 0.014 14.4 0.0 0.015 14.3 0.0 1.0 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus FAA_hydrolase_N PF09298.11 KKK42329.1 - 0.095 12.9 0.0 0.11 12.7 0.0 1.0 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal MFS_1 PF07690.16 KKK42331.1 - 3.6e-30 105.1 37.9 3.6e-30 105.1 37.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KKK42331.1 - 3e-20 72.1 19.5 3.7e-20 71.8 19.5 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 KKK42331.1 - 2.2e-07 29.8 42.1 0.0013 17.4 21.4 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein CARDB PF07705.11 KKK42334.1 - 3.5e-26 91.4 0.1 3.6e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 CARDB DUF5033 PF16436.5 KKK42334.1 - 0.035 14.1 0.2 3.4 7.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5033) Arf PF00025.21 KKK42335.1 - 4.4e-10 39.3 0.0 6.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK42335.1 - 4.8e-08 32.8 0.1 7.5e-08 32.1 0.1 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK42335.1 - 0.014 15.6 0.1 0.028 14.6 0.1 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KKK42335.1 - 0.015 14.5 0.1 0.062 12.4 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit DUF4265 PF14085.6 KKK42335.1 - 0.041 13.9 0.1 0.093 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Abhydrolase_1 PF00561.20 KKK42336.1 - 1.2e-19 71.0 0.0 6.9e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK42336.1 - 2.7e-14 53.0 0.0 3.1e-12 46.3 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK42336.1 - 2.4e-09 38.1 0.0 3.1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KKK42336.1 - 0.001 19.0 0.0 0.004 17.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KKK42336.1 - 0.0015 18.7 0.0 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 KKK42336.1 - 0.058 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase zinc_ribbon_2 PF13240.6 KKK42337.1 - 1.9e-08 33.8 3.8 2.8e-08 33.2 3.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK42337.1 - 2.1e-07 30.1 1.5 2.8e-07 29.7 1.5 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK42337.1 - 2.7e-06 27.3 0.8 4e-06 26.8 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK42337.1 - 0.0012 19.5 0.2 0.0013 19.4 0.2 1.2 1 0 0 1 1 1 1 zinc-ribbon family Nudix_N_2 PF14803.6 KKK42337.1 - 0.0014 18.5 3.4 0.13 12.2 0.3 2.2 2 0 0 2 2 2 2 Nudix N-terminal Cript PF10235.9 KKK42337.1 - 0.0015 19.0 0.1 0.0017 18.9 0.1 1.1 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT PGM_PMM_I PF02878.16 KKK42337.1 - 0.0078 15.9 0.0 0.0092 15.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I zf-C4_Topoisom PF01396.19 KKK42337.1 - 0.012 15.4 2.1 0.018 14.8 2.1 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger YhfH PF14149.6 KKK42337.1 - 0.027 14.5 5.2 0.15 12.1 0.9 2.2 1 1 1 2 2 2 0 YhfH-like protein zf-tcix PF14952.6 KKK42337.1 - 0.037 13.6 1.8 0.64 9.7 0.3 2.2 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding NOB1_Zn_bind PF08772.11 KKK42337.1 - 0.071 13.3 0.3 0.071 13.3 0.3 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like UPF0547 PF10571.9 KKK42337.1 - 0.075 13.1 6.3 0.87 9.7 6.4 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 DNA_RNApol_7kD PF03604.13 KKK42337.1 - 0.081 12.6 0.6 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit OrfB_Zn_ribbon PF07282.11 KKK42337.1 - 0.088 12.8 1.2 0.15 12.0 1.2 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L32p PF01783.23 KKK42337.1 - 0.14 12.4 0.3 0.21 11.9 0.3 1.4 1 1 0 1 1 1 0 Ribosomal L32p protein family GFA PF04828.14 KKK42337.1 - 0.16 12.4 2.6 0.47 10.8 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.10 KKK42337.1 - 0.27 11.4 3.2 0.43 10.7 0.3 2.1 1 1 0 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 KKK42337.1 - 0.42 10.2 3.0 0.75 9.4 0.5 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-NADH-PPase PF09297.11 KKK42337.1 - 0.51 10.0 3.7 1.8 8.3 3.7 1.8 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain ADK_lid PF05191.14 KKK42337.1 - 0.92 9.5 3.0 1.6 8.7 0.3 2.1 1 1 1 2 2 2 0 Adenylate kinase, active site lid RNA_POL_M_15KD PF02150.16 KKK42337.1 - 1.7 8.6 8.1 25 4.8 8.1 2.1 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit Prok-RING_1 PF14446.6 KKK42342.1 - 0.25 11.3 20.3 1.2 9.2 20.3 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 KKK42342.1 - 0.79 10.0 17.6 1 9.7 17.6 1.2 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD_4 PF16866.5 KKK42342.1 - 3 8.0 15.6 3 8.0 5.0 2.4 1 1 1 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 KKK42342.1 - 3.2 8.2 20.3 0.22 11.9 12.8 2.1 1 1 1 2 2 2 0 Ring finger domain tRNA-synt_1 PF00133.22 KKK42343.1 - 2.1e-162 541.5 7.2 2.8e-162 541.1 7.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKK42343.1 - 6.9e-25 87.8 3.6 2.1e-24 86.2 3.6 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKK42343.1 - 1.9e-18 66.4 6.1 2.6e-08 33.0 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) HNH_5 PF14279.6 KKK42343.1 - 0.088 12.7 0.4 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Rad50_zn_hook PF04423.14 KKK42343.1 - 0.16 11.8 2.4 0.57 10.1 0.1 3.0 2 0 0 2 2 2 0 Rad50 zinc hook motif PyrI_C PF02748.15 KKK42343.1 - 0.41 10.6 5.8 0.12 12.3 1.7 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TerY_C PF15616.6 KKK42343.1 - 2.1 8.5 7.6 22 5.1 1.0 4.1 3 1 0 3 3 3 0 TerY-C metal binding domain zf-trcl PF13451.6 KKK42343.1 - 7.7 6.5 6.5 1 9.3 0.1 2.9 3 0 0 3 3 3 0 Probable zinc-ribbon domain GDP_Man_Dehyd PF16363.5 KKK42344.1 - 5.5e-61 206.8 0.0 5.3e-60 203.6 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK42344.1 - 8.6e-42 143.3 0.0 1.2e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK42344.1 - 1.9e-12 46.9 0.1 1.7e-10 40.6 0.1 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KKK42344.1 - 7.3e-10 38.4 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK42344.1 - 3e-08 33.1 0.0 6.7e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KKK42344.1 - 3.5e-05 23.0 0.0 7.8e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.23 KKK42344.1 - 0.12 12.4 0.1 20 5.3 0.0 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KKK42344.1 - 0.15 11.5 0.0 5.7 6.4 0.0 3.0 3 1 1 4 4 4 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KKK42345.1 - 3.8e-49 167.9 0.1 1.5e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK42345.1 - 2.4e-46 158.2 0.0 5.8e-46 156.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK42345.1 - 2.1e-19 69.6 0.3 5.6e-14 51.8 0.5 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KKK42345.1 - 2.8e-16 59.5 0.4 4.1e-12 45.8 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KKK42345.1 - 1.4e-11 44.0 0.0 3.6e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 KKK42345.1 - 9.6e-06 25.9 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KKK42345.1 - 1.8e-05 24.7 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 KKK42345.1 - 0.0013 18.9 0.1 0.0024 18.0 0.1 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KKK42345.1 - 0.0013 18.3 0.1 0.0037 16.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK42345.1 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KKK42345.1 - 0.068 12.3 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain DZR PF12773.7 KKK42345.1 - 0.14 12.3 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 Double zinc ribbon Laminin_G_3 PF13385.6 KKK42346.1 - 2.1e-07 31.2 2.7 2.1e-07 31.2 2.7 2.0 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF2240 PF09999.9 KKK42352.1 - 8.8e-05 22.2 0.2 0.00034 20.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2240) AP4E_app_platf PF14807.6 KKK42352.1 - 0.073 13.4 0.1 0.85 10.0 0.0 2.2 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform DNA_pol_E_B PF04042.16 KKK42353.1 - 7.5e-12 45.0 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 KKK42353.1 - 1.1e-10 42.3 0.2 2.1e-10 41.4 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA_anti-codon PF01336.25 KKK42353.1 - 5e-06 26.4 0.6 1.3e-05 25.1 0.3 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 KKK42353.1 - 0.00038 20.4 0.0 0.17 11.9 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4539) Metallophos_2 PF12850.7 KKK42353.1 - 0.0049 17.1 0.0 0.013 15.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA_anti_2 PF13742.6 KKK42353.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PolC_DP2 PF03833.13 KKK42354.1 - 0 1103.0 0.0 0 1102.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 KKK42354.1 - 0.049 13.6 16.4 2.3 8.3 0.0 3.2 2 1 0 2 2 2 0 zinc-ribbons HypA PF01155.19 KKK42354.1 - 0.056 13.5 14.8 1.5 8.9 0.1 3.5 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KKK42354.1 - 0.97 8.9 17.2 9.1 5.8 0.3 4.6 4 0 0 4 4 4 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KKK42354.1 - 2.2 8.4 5.9 10 6.3 0.1 3.4 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Peptidase_M28 PF04389.17 KKK42355.1 - 3.8e-22 78.9 0.0 5.9e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 Peptidase_M42 PF05343.14 KKK42355.1 - 1.6e-08 34.0 0.0 2.6e-07 29.9 0.0 2.2 2 1 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KKK42355.1 - 0.0015 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HGD-D PF06050.13 KKK42358.1 - 6.5e-31 108.3 0.0 7.2e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component FliD_C PF07195.12 KKK42358.1 - 0.016 14.6 0.3 0.037 13.5 0.1 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus UPF0158 PF03682.13 KKK42358.1 - 0.031 14.2 0.3 0.089 12.8 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) AMP-binding PF00501.28 KKK42364.1 - 7.2e-54 183.0 0.0 8.4e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK42364.1 - 3e-14 53.7 0.2 6.1e-14 52.8 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fumerase PF05681.14 KKK42364.1 - 0.053 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Gtr1_RagA PF04670.12 KKK42365.1 - 2e-16 60.0 0.5 2.2e-16 59.9 0.5 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK42365.1 - 1.4e-14 54.0 0.2 1.6e-14 53.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK42365.1 - 5e-09 35.9 0.4 5.9e-09 35.6 0.4 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK42365.1 - 1.6e-07 31.6 0.0 2.5e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK42365.1 - 7.4e-06 26.0 0.1 1.5e-05 25.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KKK42365.1 - 3.5e-05 23.5 0.1 4.6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KKK42365.1 - 0.0027 16.9 1.8 0.65 9.1 1.8 2.4 1 1 0 1 1 1 1 G-protein alpha subunit Njmu-R1 PF15053.6 KKK42365.1 - 0.02 14.0 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family KIP1 PF07765.12 KKK42365.1 - 0.029 14.5 0.1 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 KIP1-like protein AAA_18 PF13238.6 KKK42365.1 - 0.072 13.6 0.3 0.33 11.5 0.3 1.9 1 1 0 1 1 1 0 AAA domain SIR2 PF02146.17 KKK42366.1 - 3e-49 167.3 0.0 3.7e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KKK42366.1 - 8.2e-05 22.4 0.0 0.0054 16.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain zinc_ribbon_10 PF10058.9 KKK42367.1 - 0.074 12.8 0.1 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2757 PF10955.8 KKK42367.1 - 0.079 13.2 0.1 0.87 9.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) Ras PF00071.22 KKK42368.1 - 1.8e-37 128.4 0.0 2.1e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42368.1 - 4e-23 81.9 0.0 5.3e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42368.1 - 0.0073 15.8 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family LEA_5 PF00477.17 KKK42368.1 - 0.026 15.0 0.0 0.039 14.4 0.0 1.2 1 0 0 1 1 1 0 Small hydrophilic plant seed protein Proteasome PF00227.26 KKK42369.1 - 2.3e-50 170.7 0.0 2.8e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK42369.1 - 6.5e-15 54.5 0.3 4.3e-14 51.9 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature LRR_8 PF13855.6 KKK42371.1 - 5e-08 32.6 1.5 1.8e-07 30.8 1.5 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KKK42371.1 - 0.00043 20.6 5.9 0.00043 20.6 5.9 3.7 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) TetR PF13972.6 KKK42371.1 - 0.087 12.5 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 Bacterial transcriptional repressor LRR_1 PF00560.33 KKK42371.1 - 0.1 13.2 8.8 12 6.9 0.1 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat DUF1444 PF07285.11 KKK42373.1 - 0.05 13.2 0.4 0.05 13.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) WYL_2 PF10902.8 KKK42373.1 - 0.057 13.8 0.1 0.072 13.5 0.1 1.1 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold Inj_translocase PF16928.5 KKK42374.1 - 0.02 14.3 0.2 0.027 13.9 0.2 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome SRP1_TIP1 PF00660.17 KKK42374.1 - 0.076 13.1 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Seripauperin and TIP1 family TPR_2 PF07719.17 KKK42375.1 - 0.0043 17.1 21.9 3.9 7.8 0.1 6.7 5 0 0 5 5 5 4 Tetratricopeptide repeat MIT PF04212.18 KKK42375.1 - 0.016 15.3 0.2 0.016 15.3 0.2 11.2 12 0 0 12 12 12 0 MIT (microtubule interacting and transport) domain UPF0154 PF03672.13 KKK42375.1 - 0.018 15.0 2.1 0.077 13.0 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) TPR_12 PF13424.6 KKK42375.1 - 0.042 14.1 16.0 2.9 8.2 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Macscav_rec PF03523.13 KKK42375.1 - 0.1 12.5 1.0 24 4.9 0.1 3.0 2 0 0 2 2 2 0 Macrophage scavenger receptor TPR_16 PF13432.6 KKK42375.1 - 0.19 12.4 0.3 1.1e+02 3.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK42375.1 - 1.4 8.9 25.4 2 8.4 0.7 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RHH_1 PF01402.21 KKK42376.1 - 0.0033 17.3 0.2 0.015 15.2 0.0 1.9 1 1 1 2 2 2 1 Ribbon-helix-helix protein, copG family Rho_N PF07498.12 KKK42378.1 - 0.00038 20.3 1.7 0.0011 18.9 0.0 2.4 2 1 0 2 2 2 1 Rho termination factor, N-terminal domain SAP PF02037.27 KKK42378.1 - 0.0016 18.1 0.0 0.0016 18.1 0.0 2.6 3 0 0 3 3 3 1 SAP domain Ish1 PF10281.9 KKK42378.1 - 0.0028 17.9 0.0 0.035 14.4 0.0 2.7 3 0 0 3 3 3 1 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KKK42378.1 - 0.011 15.4 0.5 0.072 12.8 0.0 2.6 3 0 0 3 3 3 0 HeH/LEM domain Gelsolin PF00626.22 KKK42378.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Gelsolin repeat Spore_III_AF PF09581.10 KKK42378.1 - 0.02 14.9 0.9 0.12 12.4 0.3 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) TMEM71 PF15121.6 KKK42378.1 - 0.029 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 TMEM71 protein family DZR PF12773.7 KKK42379.1 - 0.00067 19.6 7.6 0.53 10.4 7.6 2.5 1 1 0 1 1 1 1 Double zinc ribbon Mu-like_Com PF10122.9 KKK42379.1 - 0.011 15.2 0.8 0.011 15.2 0.8 1.9 2 1 0 2 2 2 0 Mu-like prophage protein Com zf-AN1 PF01428.16 KKK42379.1 - 0.059 13.5 2.0 0.059 13.5 2.0 3.3 2 1 1 3 3 3 0 AN1-like Zinc finger zinc-ribbons_6 PF07191.12 KKK42379.1 - 0.11 12.5 10.9 0.14 12.2 6.1 2.6 1 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 KKK42379.1 - 0.28 11.1 5.4 16 5.6 0.0 3.5 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KKK42379.1 - 0.3 11.3 11.9 0.13 12.4 1.9 3.1 1 1 2 3 3 3 0 Zinc ribbon domain zf-RanBP PF00641.18 KKK42379.1 - 0.53 9.6 0.2 0.53 9.6 0.2 3.4 3 1 0 3 3 3 0 Zn-finger in Ran binding protein and others UPF0547 PF10571.9 KKK42379.1 - 0.81 9.8 0.1 0.81 9.8 0.1 3.3 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 KKK42379.1 - 0.92 9.0 15.4 1.4 8.4 0.8 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_12 PF18658.1 KKK42379.1 - 1.4 8.5 4.5 2.3 7.9 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger C2H2-type A2L_zn_ribbon PF08792.10 KKK42379.1 - 1.4 8.7 15.9 11 5.9 0.6 4.1 3 1 1 4 4 4 0 A2L zinc ribbon domain zf-NADH-PPase PF09297.11 KKK42379.1 - 9.2 6.0 13.8 51 3.7 0.2 5.0 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain Acetyltransf_1 PF00583.25 KKK42380.1 - 1.3e-12 48.0 0.1 1.6e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK42380.1 - 2e-12 47.2 0.0 2.4e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK42380.1 - 1.4e-09 38.3 0.1 2e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK42380.1 - 2.7e-05 24.0 0.1 4.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KKK42380.1 - 3e-05 23.8 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KKK42380.1 - 0.0025 17.9 0.1 0.0075 16.3 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK42380.1 - 0.02 15.0 0.1 0.039 14.1 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KKK42380.1 - 0.028 14.6 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KKK42380.1 - 0.039 13.4 0.2 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KKK42380.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 KKK42380.1 - 0.1 13.3 0.0 0.12 13.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RuvB_N PF05496.12 KKK42381.1 - 3.8e-06 26.7 0.0 4.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KKK42381.1 - 1.1e-05 25.9 0.1 1.4e-05 25.5 0.1 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKK42381.1 - 1.2e-05 25.3 0.0 1.3e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Rad17 P-loop domain ResIII PF04851.15 KKK42381.1 - 7.5e-05 22.8 0.0 8.3e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KKK42381.1 - 0.00057 19.4 0.0 0.00061 19.3 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_7 PF12775.7 KKK42381.1 - 0.0016 18.0 0.1 0.0016 18.0 0.1 1.2 1 1 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KKK42381.1 - 0.0032 16.6 0.0 0.0035 16.4 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KKK42381.1 - 0.0056 16.1 0.0 0.0062 16.0 0.0 1.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KKK42381.1 - 0.0063 16.9 0.0 0.0069 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KKK42381.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DNA_pol3_delta2 PF13177.6 KKK42381.1 - 0.015 15.0 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 KKK42381.1 - 0.02 15.3 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KKK42381.1 - 0.025 13.8 0.0 0.026 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KKK42381.1 - 0.029 13.6 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 KKK42381.1 - 0.03 14.1 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KKK42381.1 - 0.03 14.1 0.1 0.03 14.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KKK42381.1 - 0.035 14.2 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.6 KKK42381.1 - 0.052 13.8 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KKK42381.1 - 0.053 13.2 0.1 0.055 13.2 0.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KKK42381.1 - 0.053 13.3 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein TniB PF05621.11 KKK42381.1 - 0.057 12.8 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein SRP54 PF00448.22 KKK42381.1 - 0.061 12.9 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KKK42381.1 - 0.074 13.5 0.1 0.14 12.5 0.0 1.5 2 0 0 2 2 2 0 RNA helicase AAA_6 PF12774.7 KKK42381.1 - 0.11 11.5 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 KKK42381.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase PTPlike_phytase PF14566.6 KKK42381.1 - 0.13 12.3 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate AAA_18 PF13238.6 KKK42381.1 - 0.15 12.6 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK42381.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain HTH_34 PF13601.6 KKK42383.1 - 0.035 14.3 2.4 37 4.6 0.1 4.1 4 0 0 4 4 4 0 Winged helix DNA-binding domain SurA_N PF09312.11 KKK42383.1 - 0.16 12.0 1.3 1.8 8.7 0.2 2.9 3 0 0 3 3 3 0 SurA N-terminal domain NERD PF08378.11 KKK42384.1 - 0.0044 17.5 0.1 0.015 15.8 0.1 1.9 1 0 0 1 1 1 1 Nuclease-related domain SIKE PF05769.11 KKK42384.1 - 0.022 14.7 0.4 0.32 10.9 0.3 2.1 2 0 0 2 2 2 0 SIKE family HTH_17 PF12728.7 KKK42385.1 - 0.0068 16.6 0.1 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KKK42385.1 - 0.036 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KKK42385.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CN_hydrolase PF00795.22 KKK42389.1 - 2.9e-30 105.5 0.0 3.5e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase VWA PF00092.28 KKK42390.1 - 1.3e-09 38.5 0.0 1.7e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KKK42390.1 - 0.00064 20.4 0.0 0.001 19.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KKK42390.1 - 0.0018 18.5 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 KKK42390.1 - 0.002 18.1 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 KKK42390.1 - 0.042 13.3 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 Copine FIST PF08495.10 KKK42390.1 - 0.093 12.7 0.0 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 FIST N domain DUF2140 PF09911.9 KKK42393.1 - 0.034 13.7 0.0 0.064 12.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF3603 PF12227.8 KKK42393.1 - 0.06 12.7 1.2 0.078 12.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) ASH PF15780.5 KKK42393.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin zf-ribbon_3 PF13248.6 KKK42394.1 - 9e-05 21.7 0.9 0.00013 21.2 0.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK42394.1 - 0.00036 20.1 0.6 0.00051 19.7 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DUF2116 PF09889.9 KKK42394.1 - 0.0029 17.5 8.4 0.0072 16.3 8.4 1.6 1 1 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) DZR PF12773.7 KKK42394.1 - 0.053 13.6 0.8 0.067 13.2 0.8 1.2 1 0 0 1 1 1 0 Double zinc ribbon Endonuclease_7 PF02945.15 KKK42395.1 - 3.1e-08 33.4 2.3 3.1e-08 33.4 2.3 2.2 1 1 0 2 2 2 1 Recombination endonuclease VII Amidoligase_2 PF12224.8 KKK42395.1 - 0.017 14.8 0.5 0.02 14.6 0.5 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme Flavi_DEAD PF07652.14 KKK42395.1 - 0.12 12.3 0.2 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 Flavivirus DEAD domain Stc1 PF12898.7 KKK42395.1 - 0.63 10.6 10.5 0.46 11.1 3.8 2.2 1 1 1 2 2 2 0 Stc1 domain zf-C4pol PF14260.6 KKK42395.1 - 0.89 10.1 10.9 4.7 7.7 6.8 2.8 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta CTU2 PF10288.9 KKK42395.1 - 1.1 9.6 8.2 1.5 9.1 8.2 1.3 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zinc_ribbon_10 PF10058.9 KKK42395.1 - 2.5 7.9 10.4 0.44 10.3 0.4 2.8 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein RNA_POL_M_15KD PF02150.16 KKK42395.1 - 2.8 7.9 7.4 4.2 7.3 0.5 3.2 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit gag-asp_proteas PF13975.6 KKK42397.1 - 0.16 12.6 0.0 0.24 12.0 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KKK42397.1 - 0.21 12.2 0.0 0.35 11.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF4869 PF16163.5 KKK42400.1 - 0.85 9.3 3.7 1.6 8.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4869) Pyrid_oxidase_2 PF13883.6 KKK42401.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase FliMN_C PF01052.20 KKK42402.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term SCP2_2 PF13530.6 KKK42405.1 - 4.2e-15 56.0 0.0 5.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain Acyl_transf_3 PF01757.22 KKK42409.1 - 0.06 12.4 27.7 7.2 5.6 27.7 2.2 1 1 0 1 1 1 0 Acyltransferase family Peptidase_U4 PF03419.13 KKK42409.1 - 1.2 8.3 24.7 0.016 14.5 15.2 2.0 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Hydrolase_4 PF12146.8 KKK42410.1 - 6.7e-06 25.5 0.0 9.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK42410.1 - 7.3e-05 22.5 0.0 7.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK42410.1 - 0.0026 17.3 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KKK42410.1 - 0.0097 16.0 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 KKK42410.1 - 0.01 15.4 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 KKK42410.1 - 0.015 15.0 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.13 KKK42410.1 - 0.015 14.9 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KKK42410.1 - 0.026 14.3 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LIP PF03583.14 KKK42410.1 - 0.071 12.4 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase Molybdop_Fe4S4 PF04879.16 KKK42415.1 - 4.9e-09 36.0 0.1 5.3e-09 35.9 0.1 1.0 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain adh_short PF00106.25 KKK42416.1 - 9.3e-47 159.0 0.1 1.3e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK42416.1 - 2.2e-37 128.9 0.0 2.8e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK42416.1 - 3.9e-06 26.9 0.1 6.3e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK42416.1 - 0.00048 20.1 0.1 0.00073 19.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ubie_methyltran PF01209.18 KKK42416.1 - 0.00064 19.1 0.1 0.001 18.5 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KKK42416.1 - 0.0011 19.6 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KKK42416.1 - 0.002 17.3 0.1 0.0036 16.5 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KKK42416.1 - 0.0022 18.2 0.2 0.0036 17.5 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_31 PF13847.6 KKK42416.1 - 0.0023 17.7 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain F420_oxidored PF03807.17 KKK42416.1 - 0.0079 16.7 0.1 0.034 14.7 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 KKK42416.1 - 0.031 14.1 0.1 0.16 11.8 0.1 2.0 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Methyltransf_12 PF08242.12 KKK42416.1 - 0.036 14.8 0.0 0.079 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KKK42416.1 - 0.044 13.2 0.1 0.067 12.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 KKK42416.1 - 0.045 14.4 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 KKK42416.1 - 0.075 13.3 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 KKK42416.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KKK42417.1 - 4.3e-49 166.6 0.0 5.8e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK42417.1 - 1.6e-38 132.6 0.0 1.9e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK42417.1 - 6.3e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 KR domain MTS PF05175.14 KKK42417.1 - 0.011 15.3 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KKK42417.1 - 0.018 15.7 0.0 0.046 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.23 KKK42417.1 - 0.041 14.0 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 KKK42417.1 - 0.076 13.7 0.0 0.42 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF1776 PF08643.10 KKK42417.1 - 0.1 11.9 0.0 0.32 10.3 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) UPF0146 PF03686.13 KKK42417.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) 3HCDH_N PF02737.18 KKK42417.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PLA2_B PF01735.18 KKK42418.1 - 0.21 10.0 1.7 0.3 9.5 1.7 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain TCR_zetazeta PF11628.8 KKK42418.1 - 2 8.2 7.9 0.17 11.6 1.2 2.7 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain 7TMR-DISM_7TM PF07695.11 KKK42418.1 - 2.2 8.1 20.4 1.5 8.7 13.2 2.7 1 1 1 2 2 2 0 7TM diverse intracellular signalling Cation_efflux PF01545.21 KKK42419.1 - 8e-43 146.5 27.3 1e-42 146.1 27.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1230 PF06799.11 KKK42419.1 - 2.3 8.3 4.6 5.7 7.0 0.7 2.3 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 Oxidored_FMN PF00724.20 KKK42420.1 - 1.1e-46 159.6 0.0 1.6e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TPP_enzyme_N PF02776.18 KKK42430.1 - 1.7e-48 164.5 0.0 3.1e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK42430.1 - 2.5e-32 111.5 0.0 5.1e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK42430.1 - 2.9e-15 56.4 2.2 2.2e-14 53.5 0.1 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MCR_C PF04609.12 KKK42430.1 - 0.0022 17.1 0.1 0.0046 16.1 0.1 1.5 1 0 0 1 1 1 1 Methyl-coenzyme M reductase operon protein C CO_dh PF02552.16 KKK42430.1 - 0.097 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPP_enzyme_N PF02776.18 KKK42431.1 - 3.4e-47 160.2 0.0 1.4e-46 158.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKK42431.1 - 7.7e-39 132.9 0.1 3.2e-38 130.9 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK42431.1 - 5.3e-33 113.7 0.0 1e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KKK42431.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPP_enzyme_N PF02776.18 KKK42432.1 - 2.3e-51 173.8 0.0 2.8e-50 170.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKK42432.1 - 4.6e-39 133.6 0.0 7.8e-38 129.7 0.0 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK42432.1 - 1.1e-32 112.6 0.0 2.2e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KKK42432.1 - 0.02 14.7 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DXP_synthase_N PF13292.6 KKK42432.1 - 0.041 13.1 0.0 0.34 10.1 0.0 2.4 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase LRR_8 PF13855.6 KKK42433.1 - 1.4e-10 40.8 10.1 2.5e-07 30.4 0.8 3.5 3 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 KKK42433.1 - 4e-08 33.4 11.8 2.2e-06 27.9 0.2 4.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) HEAT_2 PF13646.6 KKK42433.1 - 1.7e-06 28.3 0.0 4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats LRR_1 PF00560.33 KKK42433.1 - 8.5e-05 22.6 8.7 0.65 10.8 0.1 5.4 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KKK42433.1 - 0.0078 16.2 8.0 1 9.6 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_5 PF13306.6 KKK42433.1 - 0.018 15.0 0.6 0.062 13.3 0.3 1.9 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) DUF2162 PF09930.9 KKK42434.1 - 0.02 14.3 0.2 0.02 14.3 0.2 2.5 1 1 1 2 2 2 0 Predicted transporter (DUF2162) DUF5362 PF17319.2 KKK42434.1 - 0.19 11.6 0.2 0.19 11.6 0.2 3.6 3 1 1 4 4 4 0 Family of unknown function (DUF5362) DUF2070 PF09843.9 KKK42434.1 - 0.57 8.4 5.1 0.63 8.3 5.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MPS-4 PF17523.2 KKK42434.1 - 1.6 8.9 4.7 1.2 9.3 0.7 2.6 2 1 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 HMGL-like PF00682.19 KKK42435.1 - 3.1e-48 164.6 0.4 4.3e-48 164.2 0.4 1.2 1 0 0 1 1 1 1 HMGL-like GH43_C2 PF17851.1 KKK42435.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain LRR_4 PF12799.7 KKK42436.1 - 1.6e-22 79.2 38.8 4.1e-09 36.6 3.1 5.5 1 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK42436.1 - 7.5e-13 48.0 30.9 2e-06 27.4 1.9 5.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KKK42436.1 - 2.2e-08 33.8 16.4 0.00023 20.7 1.9 3.3 1 1 2 3 3 3 3 Leucine-rich repeat FTH PF01827.27 KKK42436.1 - 0.014 15.2 1.9 1.4 8.7 0.1 3.1 1 1 2 3 3 3 0 FTH domain LRR_1 PF00560.33 KKK42436.1 - 0.016 15.6 24.9 7.2 7.6 0.2 7.3 6 2 1 7 7 7 0 Leucine Rich Repeat TPR_19 PF14559.6 KKK42437.1 - 0.0017 18.8 0.1 0.91 10.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKK42437.1 - 0.0039 16.4 0.1 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat YfdX PF10938.8 KKK42437.1 - 0.0071 16.3 0.2 0.4 10.6 0.0 2.1 2 0 0 2 2 2 1 YfdX protein PPR PF01535.20 KKK42437.1 - 0.0085 16.3 0.2 0.15 12.4 0.0 2.7 2 1 1 3 3 3 1 PPR repeat TPR_2 PF07719.17 KKK42437.1 - 0.019 15.0 0.9 8.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK42437.1 - 0.028 15.2 0.0 3.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK42437.1 - 0.033 14.5 0.6 1.5 9.1 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK42437.1 - 0.067 13.4 0.2 5.6 7.3 0.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.6 KKK42437.1 - 0.076 13.2 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 PPR repeat family TPR_12 PF13424.6 KKK42438.1 - 8.6e-17 61.2 0.4 1.9e-06 28.1 0.0 3.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK42438.1 - 3.2e-16 58.4 6.3 0.002 17.9 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK42438.1 - 5.8e-14 51.0 3.2 0.015 15.3 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK42438.1 - 5.6e-11 42.4 0.0 7.1e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 KKK42438.1 - 5.6e-11 41.7 0.8 0.019 15.0 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK42438.1 - 2.7e-10 39.6 10.1 0.11 12.8 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KKK42438.1 - 7.2e-07 28.9 3.1 0.0098 15.7 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK42438.1 - 4.8e-05 23.8 0.0 5.6 8.1 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK42438.1 - 0.016 15.8 0.6 83 4.2 0.0 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat CLTH PF10607.9 KKK42438.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain SHNi-TPR PF10516.9 KKK42438.1 - 0.029 13.8 1.0 0.12 11.9 0.3 2.4 3 0 0 3 3 3 0 SHNi-TPR HTH_Bact PF18768.1 KKK42438.1 - 0.039 13.5 0.2 0.039 13.5 0.2 2.9 4 1 0 4 4 4 0 Helix-turn-helix bacterial domain ANAPC3 PF12895.7 KKK42438.1 - 0.076 13.2 1.8 2 8.7 0.1 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KKK42438.1 - 0.44 10.3 8.2 15 5.3 0.1 4.3 5 0 0 5 5 5 0 TPR repeat PEP-utilizers_C PF02896.18 KKK42445.1 - 1.6e-46 158.8 0.0 2.4e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP_hydrolase PF09370.10 KKK42445.1 - 0.0034 16.6 0.0 0.59 9.3 0.0 2.5 3 0 0 3 3 3 2 Phosphoenolpyruvate hydrolase-like Gp-FAR-1 PF05823.12 KKK42445.1 - 0.0063 16.9 1.5 0.0063 16.9 1.5 1.6 2 0 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DHC_N1 PF08385.12 KKK42445.1 - 0.024 13.3 0.8 0.029 13.0 0.8 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 ATP-synt PF00231.19 KKK42445.1 - 0.032 14.0 1.2 0.057 13.1 0.8 1.5 1 1 0 1 1 1 0 ATP synthase RRF PF01765.19 KKK42445.1 - 0.039 13.9 0.9 0.063 13.2 0.9 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Mating_N PF12731.7 KKK42445.1 - 0.11 12.6 0.7 1.1 9.4 0.3 2.2 2 0 0 2 2 2 0 Mating-type protein beta 1 DUF1002 PF06207.11 KKK42445.1 - 0.18 11.3 0.9 0.3 10.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) UPF0147 PF03685.13 KKK42446.1 - 6.1e-24 83.9 0.0 7.1e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) Dehydratase_hem PF13816.6 KKK42446.1 - 0.064 12.6 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase UPF0121 PF03661.13 KKK42446.1 - 0.15 11.4 0.0 9.5 5.5 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0121) UPF0147 PF03685.13 KKK42447.1 - 3.2e-24 84.8 0.1 3.7e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) UPF0121 PF03661.13 KKK42447.1 - 0.092 12.1 0.0 2 7.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) Methyltransf_25 PF13649.6 KKK42449.1 - 2.7e-18 66.5 0.0 4.6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK42449.1 - 4.4e-18 65.7 0.0 6.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK42449.1 - 1.1e-15 57.8 0.0 1.4e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK42449.1 - 4.9e-14 52.5 0.0 6.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK42449.1 - 1.7e-09 38.3 0.0 1.3e-08 35.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK42449.1 - 2.6e-09 36.8 0.0 3.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 KKK42449.1 - 1.4e-06 28.2 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 KKK42449.1 - 3.3e-05 23.3 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.18 KKK42449.1 - 0.00018 21.3 1.3 0.062 13.0 0.1 2.6 2 1 0 2 2 2 2 DNA methylase PCMT PF01135.19 KKK42449.1 - 0.00069 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KKK42449.1 - 0.00084 19.3 0.0 0.0012 18.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 KKK42449.1 - 0.0031 16.1 0.0 0.0036 15.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 KKK42449.1 - 0.0044 16.0 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 KKK42449.1 - 0.0069 15.9 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.18 KKK42449.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 KKK42449.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CCDC-167 PF15188.6 KKK42450.1 - 0.026 14.8 0.2 0.031 14.6 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TRIQK PF15168.6 KKK42450.1 - 0.028 14.3 0.2 0.031 14.2 0.2 1.1 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family XhlA PF10779.9 KKK42450.1 - 0.036 14.3 0.2 0.045 14.0 0.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Chordopox_A13L PF05961.11 KKK42451.1 - 0.0017 18.5 1.9 0.0042 17.3 1.9 1.6 1 0 0 1 1 1 1 Chordopoxvirus A13L protein Rick_17kDa_Anti PF05433.15 KKK42451.1 - 0.021 14.7 0.2 0.021 14.7 0.2 2.3 2 1 0 2 2 2 0 Glycine zipper 2TM domain Phage_holin_8 PF16931.5 KKK42451.1 - 0.95 9.5 6.4 0.24 11.4 2.8 1.9 2 1 0 2 2 2 0 Putative phage holin DUF485 PF04341.12 KKK42451.1 - 5.7 7.0 12.6 2.1 8.3 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 FlbT PF07378.11 KKK42453.1 - 0.036 14.2 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Flagellar protein FlbT DUF2532 PF10811.8 KKK42453.1 - 0.09 12.8 6.6 0.096 12.7 4.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2532) YyzF PF14116.6 KKK42453.1 - 0.15 12.1 0.8 22 5.2 0.1 2.6 2 0 0 2 2 2 0 YyzF-like protein Lipin_mid PF16876.5 KKK42454.1 - 0.057 13.6 0.0 0.06 13.5 0.0 1.1 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Cytochrom_CIII PF02085.16 KKK42455.1 - 0.025 14.9 0.2 0.029 14.7 0.2 1.2 1 0 0 1 1 1 0 Class III cytochrome C family HypA PF01155.19 KKK42455.1 - 0.074 13.1 0.1 0.083 12.9 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 KKK42455.1 - 0.11 12.5 1.7 0.22 11.5 1.7 1.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c mTERF PF02536.14 KKK42457.1 - 4.2e-19 68.6 2.5 0.00011 21.3 0.0 4.7 1 1 2 4 4 4 4 mTERF HTH_36 PF13730.6 KKK42457.1 - 8.6e-13 48.0 0.8 3.3 7.7 0.0 9.2 9 1 1 10 10 10 3 Helix-turn-helix domain DUF4099 PF13351.6 KKK42457.1 - 2.9e-08 33.9 0.1 1.8 8.9 0.0 6.9 7 1 1 8 8 7 2 Protein of unknown function (DUF4099) HTH_24 PF13412.6 KKK42457.1 - 5.3e-07 29.1 0.8 0.86 9.2 0.0 7.7 8 0 0 8 8 8 1 Winged helix-turn-helix DNA-binding Phage_X PF05155.15 KKK42457.1 - 9.5e-06 25.9 8.6 16 6.0 0.1 7.4 2 2 4 7 7 7 0 Phage X family HTH_5 PF01022.20 KKK42457.1 - 1.4e-05 24.9 0.3 0.36 10.7 0.0 5.4 4 1 1 5 5 5 1 Bacterial regulatory protein, arsR family TAL_effector PF03377.13 KKK42457.1 - 0.00071 19.8 0.0 1.2e+02 3.1 0.0 6.1 6 0 0 6 6 6 0 TAL effector repeat RUN PF02759.19 KKK42457.1 - 0.0095 15.9 0.3 1.2 9.1 0.0 2.9 2 1 0 2 2 2 1 RUN domain Myb_DNA-bind_6 PF13921.6 KKK42457.1 - 0.014 15.6 3.9 11 6.4 1.2 4.7 3 1 0 3 3 3 0 Myb-like DNA-binding domain HTH_Crp_2 PF13545.6 KKK42457.1 - 0.03 14.3 0.0 16 5.6 0.0 4.1 3 1 1 4 4 4 0 Crp-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 KKK42457.1 - 0.032 13.9 0.1 36 4.1 0.0 4.5 5 0 0 5 5 5 0 Sigma-70, region 4 DUF1884 PF08967.10 KKK42457.1 - 0.037 14.3 0.1 19 5.6 0.0 3.9 3 2 2 5 5 5 0 Domain of unknown function (DUF1884) TxDE PF18711.1 KKK42457.1 - 0.062 13.4 2.0 34 4.6 0.0 5.2 7 0 0 7 7 7 0 Toxoflavin-degrading enzyme HTH_11 PF08279.12 KKK42457.1 - 0.062 13.2 0.1 29 4.7 0.0 4.4 5 0 0 5 5 4 0 HTH domain Ubiquitin_4 PF18036.1 KKK42457.1 - 0.11 12.6 4.5 1.1e+02 3.0 0.0 5.5 6 2 1 7 7 6 0 Ubiquitin-like domain Myb_DNA-binding PF00249.31 KKK42457.1 - 0.2 11.9 4.0 11 6.3 0.1 4.5 4 2 1 5 5 4 0 Myb-like DNA-binding domain FAM167 PF11652.8 KKK42457.1 - 0.33 11.5 4.0 69 4.0 0.1 5.1 2 2 5 7 7 7 0 FAM167 GerE PF00196.19 KKK42457.1 - 0.33 10.5 13.1 4.9 6.8 0.1 6.4 7 1 1 8 8 8 0 Bacterial regulatory proteins, luxR family Phage_int_SAM_3 PF14659.6 KKK42457.1 - 4.1 7.8 7.9 1.1 9.5 1.9 3.3 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain SMI1_KNR4 PF09346.10 KKK42458.1 - 0.0084 16.5 1.0 0.013 15.9 1.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Mlf1IP PF10248.9 KKK42458.1 - 0.012 15.6 0.2 0.013 15.5 0.2 1.1 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Vac14_Fig4_bd PF11916.8 KKK42458.1 - 0.031 14.0 0.2 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Lipoprotein_10 PF03202.13 KKK42458.1 - 0.071 13.6 3.4 0.088 13.2 3.4 1.0 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region GEMIN8 PF15348.6 KKK42458.1 - 0.28 11.5 5.4 0.32 11.3 5.4 1.0 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 ABC_tran PF00005.27 KKK42459.1 - 3e-28 99.0 0.0 5.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK42459.1 - 1.5e-13 51.2 0.2 1.8e-06 28.0 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK42459.1 - 1.4e-05 25.7 0.4 3.1e-05 24.6 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK42459.1 - 7e-05 23.3 0.1 0.00012 22.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 KKK42459.1 - 0.00034 20.4 0.1 0.0013 18.6 0.1 1.8 1 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KKK42459.1 - 0.00042 19.8 0.0 0.013 15.0 0.0 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK42459.1 - 0.00048 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK42459.1 - 0.001 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_27 PF13514.6 KKK42459.1 - 0.0013 18.3 0.1 0.0058 16.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK42459.1 - 0.0054 17.0 0.1 0.018 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 KKK42459.1 - 0.016 13.9 0.1 0.11 11.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK42459.1 - 0.031 14.4 0.2 0.23 11.5 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase MoaC PF01967.21 KKK42460.1 - 2.7e-46 157.0 1.7 3.3e-46 156.8 1.7 1.0 1 0 0 1 1 1 1 MoaC family Radical_SAM PF04055.21 KKK42461.1 - 5.7e-28 98.4 0.1 1e-27 97.5 0.1 1.5 2 0 0 2 2 2 1 Radical SAM superfamily Mob_synth_C PF06463.13 KKK42461.1 - 2.6e-17 63.0 0.2 5.5e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Fer4_14 PF13394.6 KKK42461.1 - 1.9e-08 34.4 1.0 1.9e-08 34.4 1.0 2.1 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK42461.1 - 2.6e-06 27.8 0.3 6.5e-06 26.5 0.3 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain ThiS PF02597.20 KKK42462.1 - 2.4e-11 44.1 0.1 2.9e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 ThiS family TSP9 PF11493.8 KKK42462.1 - 0.029 15.0 0.0 0.047 14.4 0.0 1.3 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 MoaE PF02391.17 KKK42463.1 - 1.6e-24 86.4 0.1 1.8e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 MoaE protein ACT_4 PF13291.6 KKK42463.1 - 0.079 13.6 0.6 14 6.4 0.1 2.8 3 1 0 3 3 3 0 ACT domain MoeA_N PF03453.17 KKK42464.1 - 1.4e-36 125.7 0.0 2e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KKK42464.1 - 2.9e-22 78.9 0.0 5.2e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KKK42464.1 - 3.1e-06 27.2 0.0 3.9e-05 23.8 0.0 2.7 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) T2SSE PF00437.20 KKK42464.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MoCF_biosynth PF00994.24 KKK42465.1 - 9e-28 96.7 0.0 1.1e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain Fcf2 PF08698.11 KKK42465.1 - 0.48 10.8 3.0 0.64 10.5 1.5 1.9 2 0 0 2 2 2 0 Fcf2 pre-rRNA processing MoeA_N PF03453.17 KKK42466.1 - 4e-43 146.9 0.0 1.6e-42 145.0 0.0 1.9 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 KKK42466.1 - 8.1e-28 96.9 0.1 1.8e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 KKK42466.1 - 1.9e-13 50.4 0.1 7.4e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) FTR1 PF03239.14 KKK42467.1 - 1.3e-35 123.0 19.8 2.2e-35 122.3 19.8 1.4 1 1 0 1 1 1 1 Iron permease FTR1 family PMP22_Claudin PF00822.20 KKK42467.1 - 0.9 9.4 9.5 0.14 12.0 1.7 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF2631 PF10939.8 KKK42467.1 - 6 6.8 5.9 23 4.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2631) DUF2207 PF09972.9 KKK42468.1 - 0.46 9.2 26.9 0.18 10.5 3.5 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) AAA_3 PF07726.11 KKK42469.1 - 1.1e-20 73.8 0.0 2.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK42469.1 - 9.3e-19 67.8 0.0 2.2e-18 66.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KKK42469.1 - 1.7e-14 53.9 0.0 3.5e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 KKK42469.1 - 3e-08 34.2 0.0 9.2e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKK42469.1 - 1.5e-06 27.7 0.0 0.013 14.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KKK42469.1 - 4.4e-06 26.5 0.0 0.021 14.6 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KKK42469.1 - 1.5e-05 25.2 0.0 3.7e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KKK42469.1 - 2.3e-05 24.9 0.0 5.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KKK42469.1 - 3.1e-05 24.5 0.0 0.0001 22.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KKK42469.1 - 4.4e-05 23.6 0.1 0.00043 20.4 0.0 2.4 2 1 0 2 2 1 1 Sigma-54 interaction domain TsaE PF02367.17 KKK42469.1 - 9e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 KKK42469.1 - 0.00026 20.8 0.7 0.06 13.1 0.0 2.7 2 1 1 3 3 3 1 DNA polymerase III, delta subunit T2SSE PF00437.20 KKK42469.1 - 0.00032 19.8 0.1 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 KKK42469.1 - 0.00042 20.9 0.0 0.026 15.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KKK42469.1 - 0.0016 18.7 0.0 0.0048 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK42469.1 - 0.0028 17.6 0.1 0.0061 16.5 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MCM PF00493.23 KKK42469.1 - 0.0032 16.6 0.0 0.094 11.8 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_14 PF13173.6 KKK42469.1 - 0.0036 17.3 0.0 0.01 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KKK42469.1 - 0.0048 16.1 0.1 0.029 13.6 0.0 2.1 2 1 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 KKK42469.1 - 0.0052 16.5 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein ResIII PF04851.15 KKK42469.1 - 0.006 16.6 0.1 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 KKK42469.1 - 0.011 15.0 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Thymidylate_kin PF02223.17 KKK42469.1 - 0.012 15.3 0.0 1.3 8.7 0.0 3.0 2 1 1 3 3 3 0 Thymidylate kinase NACHT PF05729.12 KKK42469.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Bac_DnaA PF00308.18 KKK42469.1 - 0.027 14.3 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein DUF815 PF05673.13 KKK42469.1 - 0.044 12.9 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KKK42469.1 - 0.048 13.6 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 1 0 NTPase AAA_30 PF13604.6 KKK42469.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 KKK42469.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KKK42469.1 - 0.092 12.9 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain VWA PF00092.28 KKK42470.1 - 4.5e-12 46.6 0.1 8e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KKK42470.1 - 2.8e-07 31.1 0.2 6.6e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KKK42470.1 - 0.00097 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CobT_C PF11775.8 KKK42470.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Bac_luciferase PF00296.20 KKK42471.1 - 0.00012 21.6 0.0 0.00012 21.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 KKK42472.1 - 4.8e-30 105.1 0.0 5.5e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase YnfE PF17452.2 KKK42472.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized YnfE-like Methyltransf_3 PF01596.17 KKK42473.1 - 8.9e-19 67.5 0.8 1.5e-16 60.2 0.1 2.0 1 1 1 2 2 2 2 O-methyltransferase Methyltransf_24 PF13578.6 KKK42473.1 - 1.4e-10 42.1 0.0 2.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 KKK42473.1 - 0.006 16.3 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.7 KKK42473.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ras PF00071.22 KKK42474.1 - 1.5e-33 115.7 0.1 1.7e-33 115.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42474.1 - 6.3e-26 91.0 0.0 1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42474.1 - 1.4e-10 40.9 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42474.1 - 2.5e-06 27.0 0.2 3.7e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KKK42474.1 - 0.018 14.8 0.1 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_VLTF3 PF04947.14 KKK42474.1 - 0.025 14.3 2.0 3.4 7.4 0.4 2.2 1 1 1 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like AAA PF00004.29 KKK42474.1 - 0.028 14.9 0.0 0.065 13.7 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK42474.1 - 0.035 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KKK42474.1 - 1.7 9.2 3.6 5.8 7.5 3.6 2.0 1 1 0 1 1 1 0 AAA domain Pyrophosphatase PF00719.19 KKK42475.1 - 6.9e-46 156.0 1.0 7.8e-46 155.8 1.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF169 PF02596.15 KKK42476.1 - 3.2e-29 102.3 0.1 9.3e-27 94.3 0.1 2.0 1 1 0 1 1 1 1 Uncharacterised ArCR, COG2043 Sec5 PF15469.6 KKK42477.1 - 0.0031 17.3 0.1 0.0048 16.7 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Glycoamylase PF10091.9 KKK42477.1 - 0.06 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative glucoamylase Nre_N PF04894.12 KKK42480.1 - 2.2e-84 283.5 0.0 2.8e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Archaeal Nre, N-terminal Nre_C PF04895.12 KKK42480.1 - 2.1e-33 114.5 0.1 5.3e-33 113.2 0.1 1.7 1 0 0 1 1 1 1 Archaeal Nre, C-terminal Y_Y_Y PF07495.13 KKK42481.1 - 0.12 12.3 0.9 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Y_Y_Y domain DUF4976 PF16347.5 KKK42484.1 - 0.053 13.8 0.7 0.062 13.6 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) NMO PF03060.15 KKK42486.1 - 2.3e-30 106.2 0.1 2.3e-29 102.8 0.1 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK42486.1 - 8.1e-07 28.3 0.1 8.6e-06 25.0 0.1 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KKK42486.1 - 0.00027 20.5 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 KKK42486.1 - 0.0006 19.2 0.3 0.0011 18.3 0.3 1.4 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KKK42486.1 - 0.031 13.4 1.0 0.093 11.8 1.0 1.8 1 1 0 1 1 1 0 Conserved region in glutamate synthase FMN_dh PF01070.18 KKK42486.1 - 0.043 12.8 0.2 0.062 12.3 0.2 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DHO_dh PF01180.21 KKK42486.1 - 0.11 11.7 0.2 0.25 10.5 0.1 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NanE PF04131.14 KKK42486.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 KKK42486.1 - 0.18 11.1 0.1 0.43 9.9 0.1 1.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase Citrate_bind PF16114.5 KKK42493.1 - 1.1e-39 135.7 0.0 1.6e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KKK42493.1 - 2e-14 53.6 0.0 3.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain 4HBT PF03061.22 KKK42494.1 - 2.9e-17 62.8 0.0 3.7e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KKK42494.1 - 9.2e-08 32.6 0.0 1.3e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 KKK42494.1 - 0.016 15.3 0.0 0.019 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) YiiD_C PF09500.10 KKK42494.1 - 0.039 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) PIN_2 PF10130.9 KKK42496.1 - 9.2e-27 93.9 1.5 1.1e-26 93.6 1.5 1.1 1 0 0 1 1 1 1 PIN domain PIN PF01850.21 KKK42496.1 - 8.4e-06 26.3 1.1 1.2e-05 25.8 1.1 1.2 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 KKK42496.1 - 0.00046 20.9 0.0 0.00075 20.2 0.0 1.4 1 0 0 1 1 1 1 PIN domain Pyr_redox_2 PF07992.14 KKK42497.1 - 1.1e-48 166.0 0.0 1.3e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK42497.1 - 1.8e-20 73.3 0.0 3.5e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKK42497.1 - 4e-17 62.5 0.0 9e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK42497.1 - 1.3e-13 50.9 0.5 1.7e-13 50.5 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KKK42497.1 - 0.026 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NES_C_h PF18208.1 KKK42497.1 - 0.077 13.3 0.1 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain K_oxygenase PF13434.6 KKK42497.1 - 0.11 11.6 0.0 0.29 10.2 0.0 1.5 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Imm42 PF15593.6 KKK42499.1 - 0.0025 18.3 0.2 0.0035 17.8 0.2 1.2 1 0 0 1 1 1 1 Immunity protein 42 MatP_C PF17414.2 KKK42499.1 - 0.019 15.2 1.6 0.027 14.6 1.3 1.5 1 1 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain PSK_trans_fac PF07704.11 KKK42499.1 - 0.071 13.9 0.1 0.094 13.5 0.1 1.1 1 0 0 1 1 1 0 Rv0623-like transcription factor CREPT PF16566.5 KKK42499.1 - 0.12 12.5 3.8 0.14 12.3 3.8 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour RHH_1 PF01402.21 KKK42499.1 - 0.17 11.8 1.8 0.64 10.0 0.9 2.5 2 1 1 3 3 3 0 Ribbon-helix-helix protein, copG family Peptidase_M20 PF01546.28 KKK42500.1 - 1.7e-35 122.6 0.0 2.2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK42500.1 - 6.6e-26 90.4 0.0 1e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK42500.1 - 3.2e-05 23.7 0.2 0.00034 20.4 0.2 2.3 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 KKK42500.1 - 0.0034 16.5 0.1 0.41 9.6 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase RNA_pol_Rpb4 PF03874.16 KKK42500.1 - 0.12 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 Succ_CoA_lig PF13607.6 KKK42503.1 - 7.5e-46 155.4 0.0 6.2e-44 149.2 0.0 2.2 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain POR_N PF01855.19 KKK42517.1 - 1.4e-08 34.8 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TPP_enzyme_C PF02775.21 KKK42518.1 - 1e-27 96.8 1.0 1.5e-27 96.3 1.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 KKK42518.1 - 6.2e-21 74.3 1.8 1.2e-20 73.4 1.8 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal G3P_antiterm PF04309.12 KKK42518.1 - 0.035 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator FAD_binding_2 PF00890.24 KKK42519.1 - 1.2e-101 340.8 0.3 1.5e-101 340.5 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KKK42519.1 - 3.7e-31 107.8 0.0 5.7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 KKK42519.1 - 5.9e-07 29.4 0.3 1.2e-05 25.1 0.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KKK42519.1 - 0.017 14.4 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KKK42519.1 - 0.02 14.2 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Fer2_3 PF13085.6 KKK42520.1 - 5.8e-27 93.9 0.0 1.4e-26 92.6 0.0 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 KKK42520.1 - 2e-05 25.0 1.6 2e-05 25.0 1.6 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KKK42520.1 - 3.1e-05 23.9 0.6 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KKK42520.1 - 0.00059 20.3 2.2 0.00059 20.3 2.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK42520.1 - 0.00068 19.7 3.1 0.00068 19.7 3.1 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain C6_DPF PF10170.9 KKK42520.1 - 0.03 14.7 2.1 0.075 13.4 0.0 2.1 2 0 0 2 2 2 0 Cysteine-rich domain Fer4_9 PF13187.6 KKK42520.1 - 2.5 8.4 11.7 0.1 12.8 3.3 2.8 2 2 2 4 4 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK42520.1 - 2.9 8.9 9.6 0.33 11.9 3.9 2.3 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK42520.1 - 9.1 7.0 11.2 0.46 11.1 4.5 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain OrfB_Zn_ribbon PF07282.11 KKK42521.1 - 0.016 15.1 0.4 0.025 14.5 0.4 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Cys_rich_CPCC PF14206.6 KKK42521.1 - 0.019 14.8 0.2 0.026 14.3 0.2 1.2 1 0 0 1 1 1 0 Cysteine-rich CPCC CxC4 PF18717.1 KKK42521.1 - 0.037 13.9 0.3 0.044 13.6 0.3 1.1 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases C1_1 PF00130.22 KKK42521.1 - 0.038 13.9 0.5 0.053 13.4 0.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KKK42521.1 - 0.056 13.8 2.6 0.078 13.3 2.6 1.3 1 0 0 1 1 1 0 C1 domain DUF2318 PF10080.9 KKK42521.1 - 0.061 13.4 1.0 0.076 13.1 1.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) A2L_zn_ribbon PF08792.10 KKK42521.1 - 0.077 12.7 3.9 0.12 12.2 3.9 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.13 KKK42521.1 - 0.079 12.7 1.6 0.41 10.4 0.3 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 KKK42521.1 - 0.097 12.6 2.2 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 KKK42521.1 - 0.15 12.1 0.4 0.19 11.8 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-H2C2_2 PF13465.6 KKK42521.1 - 0.28 11.7 2.6 2.4 8.7 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KKK42521.1 - 0.55 10.4 3.0 2.6 8.2 2.6 2.0 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KKK42521.1 - 0.59 9.9 4.8 6.9 6.5 0.8 2.2 2 0 0 2 2 2 0 zinc-ribbon domain SCP2 PF02036.17 KKK42522.1 - 0.0018 18.7 0.0 0.0025 18.3 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Laminin_G_3 PF13385.6 KKK42523.1 - 1.1e-15 58.1 0.1 2.1e-14 53.9 0.1 2.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF5416 PF17437.2 KKK42523.1 - 0.12 12.2 2.1 0.098 12.4 0.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5416) Alpha_L_fucos PF01120.17 KKK42524.1 - 9.4e-96 321.3 14.9 1.1e-95 321.1 14.9 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 KKK42524.1 - 2.9e-05 24.3 0.1 5.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 Abhydrolase_1 PF00561.20 KKK42528.1 - 6.6e-15 55.4 0.0 7.5e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK42528.1 - 2.5e-06 26.9 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK42528.1 - 6.6e-06 26.9 0.0 7.6e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KKK42528.1 - 0.0004 19.2 0.0 0.00054 18.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 KKK42528.1 - 0.022 14.2 0.0 6.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 KKK42528.1 - 0.063 12.9 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase ThiG PF05690.14 KKK42528.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 KKK42529.1 - 1.4e-62 211.7 50.2 9e-51 172.8 26.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK42529.1 - 2.5e-12 46.4 26.0 3.6e-08 32.7 10.0 2.5 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KKK42529.1 - 2.1e-10 40.1 9.7 2.1e-10 40.1 9.7 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KKK42529.1 - 4.7e-07 28.6 9.1 6.4e-07 28.1 9.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 KKK42529.1 - 6.4e-07 28.3 27.9 0.00017 20.3 18.3 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_4 PF06779.14 KKK42529.1 - 0.00012 21.5 2.0 0.00012 21.5 2.0 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OAD_gamma PF04277.13 KKK42529.1 - 0.041 14.5 0.2 0.42 11.2 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3185 PF11381.8 KKK42529.1 - 0.095 12.7 0.5 0.095 12.7 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3185) Abhydrolase_1 PF00561.20 KKK42530.1 - 2.7e-19 69.8 0.0 1.7e-16 60.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK42530.1 - 4.8e-11 42.4 0.0 1.1e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK42530.1 - 8.9e-07 29.7 0.0 1.4e-06 29.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KKK42530.1 - 0.00028 20.7 0.0 0.037 13.8 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.14 KKK42530.1 - 0.00038 19.3 0.0 0.00068 18.4 0.0 1.4 1 1 0 1 1 1 1 Ndr family FSH1 PF03959.13 KKK42530.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) UPF0227 PF05728.12 KKK42530.1 - 0.02 14.8 0.0 0.32 10.9 0.0 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.21 KKK42530.1 - 0.021 14.3 0.0 20 4.6 0.0 3.8 4 1 1 5 5 5 0 Prolyl oligopeptidase family DUF2048 PF09752.9 KKK42530.1 - 0.04 13.0 0.1 0.06 12.4 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Peptidase_S15 PF02129.18 KKK42530.1 - 0.083 12.5 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Patatin PF01734.22 KKK42530.1 - 0.22 11.7 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Patatin-like phospholipase Flavodoxin_5 PF12724.7 KKK42531.1 - 7.4e-14 52.2 0.0 1.2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 KKK42531.1 - 1.1e-10 41.9 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 KKK42531.1 - 1.1e-10 41.4 1.4 1.3e-09 38.0 0.2 2.2 1 1 0 2 2 2 1 Flavodoxin domain Fer4 PF00037.27 KKK42531.1 - 5e-09 35.6 13.7 5.9e-05 22.7 3.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK42531.1 - 9.4e-07 28.9 12.0 2.4e-06 27.6 12.1 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK42531.1 - 1.3e-06 28.8 1.7 0.035 14.7 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK42531.1 - 2.1e-06 28.6 8.2 0.007 17.3 0.2 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK42531.1 - 2.2e-06 28.0 2.0 0.02 15.3 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK42531.1 - 4.3e-06 27.2 11.5 7.1e-05 23.3 12.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK42531.1 - 7.1e-06 26.0 13.5 5.3e-05 23.2 14.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK42531.1 - 3.6e-05 23.6 12.6 0.0098 15.9 3.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Flavodoxin_4 PF12682.7 KKK42531.1 - 0.00044 20.0 0.5 0.38 10.4 0.1 2.8 2 1 1 3 3 3 2 Flavodoxin Fer4_2 PF12797.7 KKK42531.1 - 0.0015 18.5 12.4 0.036 14.2 2.7 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK42531.1 - 0.011 15.8 12.9 0.1 12.7 1.7 2.2 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK42531.1 - 2 9.5 14.8 0.77 10.8 2.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 KKK42531.1 - 9.9 6.4 11.8 2.3 8.4 3.0 2.8 2 1 1 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S PEMT PF04191.13 KKK42532.1 - 9.1e-10 38.9 0.9 1.7e-09 38.1 0.5 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 KKK42532.1 - 0.0005 20.4 2.2 0.00055 20.3 0.3 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KKK42532.1 - 0.011 15.3 4.3 0.024 14.2 4.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DUF4229 PF14012.6 KKK42532.1 - 0.18 11.9 2.6 0.37 10.9 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) DUF4145 PF13643.6 KKK42533.1 - 0.00012 22.2 0.3 0.00028 20.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) DUF2225 PF09986.9 KKK42533.1 - 0.0072 16.1 2.6 0.011 15.5 0.9 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF86 PF01934.17 KKK42533.1 - 0.012 15.4 0.5 0.024 14.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF86 Abi_2 PF07751.11 KKK42533.1 - 0.015 15.6 1.9 0.033 14.4 1.8 1.5 1 1 0 1 1 1 0 Abi-like protein HEPN_Apea PF18739.1 KKK42533.1 - 0.021 15.3 5.5 0.12 12.8 5.5 2.4 1 1 0 1 1 1 0 Apea-like HEPN UPF0547 PF10571.9 KKK42533.1 - 0.025 14.6 0.5 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 GSH-S_ATP PF02955.16 KKK42533.1 - 0.05 13.0 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain IBR PF01485.21 KKK42533.1 - 0.057 13.6 0.5 9.5 6.5 0.0 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 KKK42533.1 - 0.16 11.4 1.5 5.4 6.6 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK42533.1 - 0.42 10.4 3.4 1.3 8.8 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF2089 PF09862.9 KKK42533.1 - 0.97 9.5 4.0 2.6 8.1 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2089) RecR PF02132.15 KKK42533.1 - 2.1 8.0 3.7 14 5.3 0.1 2.8 3 0 0 3 3 3 0 RecR protein Glyco_transf_5 PF08323.11 KKK42534.1 - 0.002 17.8 0.1 0.0027 17.4 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain His_Phos_1 PF00300.22 KKK42534.1 - 0.037 13.7 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) zinc-ribbons_6 PF07191.12 KKK42539.1 - 0.0003 20.7 2.8 0.00044 20.2 2.8 1.2 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.7 KKK42539.1 - 0.0036 17.3 2.0 0.005 16.8 2.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon FYVE PF01363.21 KKK42539.1 - 0.025 14.7 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 FYVE zinc finger Desulfoferrod_N PF06397.12 KKK42539.1 - 0.047 13.3 0.2 0.083 12.5 0.2 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain OrfB_Zn_ribbon PF07282.11 KKK42539.1 - 0.065 13.2 4.6 0.12 12.3 4.6 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 KKK42539.1 - 0.089 12.5 3.3 0.15 11.8 3.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.6 KKK42539.1 - 0.096 13.5 4.1 0.16 12.8 4.1 1.3 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon HypA PF01155.19 KKK42539.1 - 0.096 12.7 1.1 0.14 12.2 1.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DSL PF01414.19 KKK42539.1 - 0.099 12.9 2.0 0.16 12.2 2.0 1.3 1 0 0 1 1 1 0 Delta serrate ligand zf-Mss51 PF13824.6 KKK42539.1 - 0.21 11.7 6.1 0.22 11.7 3.3 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.6 KKK42539.1 - 0.26 10.7 2.2 14 5.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 KKK42539.1 - 0.39 10.3 3.2 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C4_Topoisom PF01396.19 KKK42539.1 - 1.4 8.7 6.4 5.7 6.8 6.6 1.9 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger YhfH PF14149.6 KKK42539.1 - 9.7 6.3 10.7 47 4.1 9.9 2.1 1 1 1 2 2 2 0 YhfH-like protein DUF2120 PF09893.9 KKK42540.1 - 0.061 13.4 0.3 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Glyoxalase_2 PF12681.7 KKK42540.1 - 0.065 13.2 0.5 0.6 10.0 0.1 2.3 2 0 0 2 2 2 0 Glyoxalase-like domain AAA PF00004.29 KKK42542.1 - 1.2e-25 90.5 0.0 8.5e-25 87.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK42542.1 - 4.1e-05 24.0 0.1 0.00073 20.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KKK42542.1 - 0.00011 22.3 0.2 0.0014 18.7 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KKK42542.1 - 0.0002 21.1 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KKK42542.1 - 0.00027 21.1 0.0 0.00061 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK42542.1 - 0.00027 20.7 0.0 0.0015 18.3 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KKK42542.1 - 0.00031 20.7 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KKK42542.1 - 0.00055 19.5 1.0 0.0094 15.5 0.0 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KKK42542.1 - 0.00069 20.2 0.1 0.0023 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KKK42542.1 - 0.00086 18.5 0.1 0.0042 16.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KKK42542.1 - 0.001 19.3 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK42542.1 - 0.0011 18.9 1.5 0.15 11.9 0.0 3.0 1 1 2 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK42542.1 - 0.0024 18.1 0.3 0.018 15.3 0.1 2.4 2 1 0 2 2 1 1 AAA domain KAP_NTPase PF07693.14 KKK42542.1 - 0.0042 16.4 0.0 0.013 14.7 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.6 KKK42542.1 - 0.0051 16.8 0.6 0.012 15.6 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KKK42542.1 - 0.014 15.7 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK42542.1 - 0.026 14.9 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 1 0 RNA helicase Hydin_ADK PF17213.3 KKK42542.1 - 0.031 14.6 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NACHT PF05729.12 KKK42542.1 - 0.048 13.6 0.1 0.38 10.7 0.0 2.3 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 KKK42542.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 KKK42542.1 - 0.066 13.5 0.1 0.24 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KKK42542.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KKK42542.1 - 0.084 13.0 0.1 0.61 10.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KKK42542.1 - 0.088 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK42542.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK42542.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK42542.1 - 0.21 11.0 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AT_hook PF02178.19 KKK42548.1 - 0.043 13.7 1.2 0.043 13.7 1.2 2.3 2 0 0 2 2 2 0 AT hook motif MFS_Mycoplasma PF07672.13 KKK42549.1 - 0.089 12.1 4.8 0.094 12.0 4.8 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF2207 PF09972.9 KKK42549.1 - 5.1 5.8 6.6 5.5 5.6 6.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MMR_HSR1_C PF08438.10 KKK42550.1 - 9.1e-28 97.1 0.1 1.6e-27 96.3 0.1 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KKK42550.1 - 4.5e-18 65.4 0.0 4e-17 62.3 0.0 2.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 KKK42550.1 - 5.4e-07 29.6 0.1 1.8e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 KKK42550.1 - 5.1e-06 26.1 0.2 0.00012 21.6 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KKK42550.1 - 0.05 13.7 0.4 0.48 10.4 0.0 2.5 2 1 1 3 3 2 0 Dynamin family MgtE PF01769.16 KKK42551.1 - 0.0023 18.3 0.5 0.0025 18.2 0.5 1.1 1 0 0 1 1 1 1 Divalent cation transporter DUF2207 PF09972.9 KKK42551.1 - 0.031 13.1 1.5 0.032 13.0 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 KKK42551.1 - 0.36 10.5 3.5 0.55 9.9 3.5 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4231 PF14015.6 KKK42551.1 - 0.52 10.8 2.1 0.71 10.4 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Cpn60_TCP1 PF00118.24 KKK42553.1 - 6.4e-172 572.6 19.7 7.3e-172 572.4 19.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribo_biogen_C PF04034.13 KKK42554.1 - 2.2e-33 114.7 0.1 2.9e-33 114.3 0.1 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KKK42554.1 - 2.3e-08 33.7 0.3 4.4e-08 32.8 0.3 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MAPKK1_Int PF08923.10 KKK42555.1 - 4.1e-05 23.4 0.2 7.3e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Robl_LC7 PF03259.17 KKK42555.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Roadblock/LC7 domain TM231 PF10149.9 KKK42556.1 - 0.048 13.0 0.1 0.052 12.9 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 Ras PF00071.22 KKK42560.1 - 2.5e-39 134.5 0.1 3e-39 134.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42560.1 - 1.7e-26 92.8 0.0 3.6e-26 91.7 0.0 1.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42560.1 - 2.4e-09 36.9 0.0 2.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42560.1 - 0.0034 16.8 0.0 0.0043 16.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK42560.1 - 0.0038 16.7 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK42560.1 - 0.037 14.1 0.0 0.072 13.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase SUI1 PF01253.22 KKK42561.1 - 6.6e-16 58.6 0.2 8e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DTW PF03942.15 KKK42561.1 - 0.018 14.8 0.8 0.023 14.4 0.7 1.3 1 1 0 1 1 1 0 DTW domain Bcl-2 PF00452.19 KKK42561.1 - 0.066 13.9 0.0 0.072 13.8 0.0 1.2 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family tRNA_anti-codon PF01336.25 KKK42563.1 - 3.2e-23 81.5 9.3 7.2e-07 29.1 0.1 5.3 5 1 0 5 5 5 4 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KKK42563.1 - 1.3e-14 54.5 7.4 6e-05 22.9 0.1 3.4 3 1 0 3 3 3 3 Cell division control protein 24, OB domain 3 REPA_OB_2 PF16900.5 KKK42563.1 - 7e-14 51.5 9.4 0.0014 18.5 0.3 4.7 4 0 0 4 4 4 4 Replication protein A OB domain Rep_fac-A_C PF08646.10 KKK42563.1 - 3.8e-12 46.2 4.8 5.8e-09 35.9 1.0 4.4 4 0 0 4 4 4 1 Replication factor-A C terminal domain POT1PC PF16686.5 KKK42563.1 - 1e-05 25.5 2.6 0.71 9.7 0.2 3.6 2 1 0 3 3 3 2 ssDNA-binding domain of telomere protection protein DUF2240 PF09999.9 KKK42563.1 - 4.3e-05 23.2 1.4 5.5e-05 22.8 0.2 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2240) DUF4539 PF15072.6 KKK42563.1 - 6.4e-05 22.9 0.1 0.0053 16.8 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4539) DUF3127 PF11325.8 KKK42563.1 - 0.013 15.8 6.3 0.05 13.9 0.1 4.6 4 3 0 4 4 4 0 Domain of unknown function (DUF3127) Methyltransf_31 PF13847.6 KKK42563.1 - 0.045 13.5 0.3 7.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Aegerolysin PF06355.13 KKK42563.1 - 0.1 12.7 3.2 1.1 9.3 0.5 2.8 1 1 1 2 2 2 0 Aegerolysin Invas_SpaK PF03519.14 KKK42563.1 - 0.29 11.2 5.7 0.63 10.1 0.1 3.1 3 0 0 3 3 3 0 Invasion protein B family UvrB_inter PF17757.1 KKK42563.1 - 4.7 7.5 9.5 2.1 8.6 0.1 4.6 5 2 2 7 7 7 0 UvrB interaction domain His_biosynth PF00977.21 KKK42564.1 - 2.9e-37 128.4 0.2 3.2e-37 128.2 0.2 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF3388 PF11868.8 KKK42564.1 - 0.0059 16.0 0.4 0.0082 15.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) CdiI_3 PF18616.1 KKK42564.1 - 0.01 15.7 1.5 0.14 12.0 0.0 2.9 3 0 0 3 3 3 0 CDI immunity proteins IGPS PF00218.21 KKK42564.1 - 0.042 13.0 0.1 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Prok-RING_1 PF14446.6 KKK42565.1 - 9.5e-06 25.5 5.5 0.0002 21.2 2.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KKK42565.1 - 7.8e-05 22.9 7.2 0.00013 22.2 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain C1_2 PF03107.16 KKK42565.1 - 0.0032 17.7 1.5 0.024 14.9 0.2 2.3 2 0 0 2 2 2 1 C1 domain C1_1 PF00130.22 KKK42565.1 - 0.004 17.0 5.2 0.031 14.2 1.4 2.3 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ALP_N PF17989.1 KKK42565.1 - 0.0047 17.1 0.0 0.0068 16.6 0.0 1.3 1 1 0 1 1 1 1 Actin like proteins N terminal domain zf-ribbon_3 PF13248.6 KKK42565.1 - 0.0062 15.9 6.4 0.077 12.4 2.1 2.6 2 0 0 2 2 2 1 zinc-ribbon domain Prok-RING_4 PF14447.6 KKK42565.1 - 0.016 15.1 6.3 1.3 8.9 1.3 2.8 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KKK42565.1 - 0.02 14.8 8.3 1.3 8.9 2.4 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 KKK42565.1 - 0.03 14.3 6.0 0.23 11.5 4.2 2.4 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 KKK42565.1 - 0.038 14.0 6.5 0.7 10.0 6.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-piccolo PF05715.13 KKK42565.1 - 0.047 13.8 3.6 1.6 8.9 0.2 3.2 3 0 0 3 3 3 0 Piccolo Zn-finger DUF4428 PF14471.6 KKK42565.1 - 0.16 11.9 5.3 5.3 7.0 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) Zn_ribbon_17 PF17120.5 KKK42565.1 - 0.21 11.2 6.3 0.35 10.5 6.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HypA PF01155.19 KKK42565.1 - 0.24 11.4 6.6 2.7 8.1 6.3 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KKK42565.1 - 0.28 11.5 10.0 3.2 8.1 4.5 3.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DNA_ligase_ZBD PF03119.16 KKK42565.1 - 0.29 11.2 4.9 14 5.8 0.2 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 KKK42565.1 - 0.3 11.2 8.4 0.31 11.2 2.1 2.7 1 1 1 2 2 2 0 Zinc ribbon domain DUF4796 PF16044.5 KKK42565.1 - 0.44 10.1 4.8 4.2 6.9 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4796) zinc_ribbon_16 PF17034.5 KKK42565.1 - 0.47 10.7 7.5 0.21 11.8 1.7 2.2 1 1 1 2 2 2 0 Zinc-ribbon like family YacG PF03884.14 KKK42565.1 - 0.58 9.9 6.2 5.9 6.7 1.0 2.6 1 1 1 2 2 2 0 DNA gyrase inhibitor YacG zinc_ribbon_4 PF13717.6 KKK42565.1 - 1.6 8.7 8.5 7.6 6.6 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-B_box PF00643.24 KKK42565.1 - 3.1 8.0 8.4 1.1 9.4 2.9 2.5 2 1 0 2 2 2 0 B-box zinc finger zf-C2H2_4 PF13894.6 KKK42565.1 - 4.4 8.4 6.4 42 5.4 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger OrfB_Zn_ribbon PF07282.11 KKK42565.1 - 5.6 7.0 6.7 5 7.1 2.2 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L37ae PF01780.19 KKK42565.1 - 5.9 7.0 6.8 18 5.5 0.4 2.4 1 1 1 2 2 2 0 Ribosomal L37ae protein family Sgf11 PF08209.11 KKK42565.1 - 6 6.5 6.7 8.5 6.0 0.2 2.8 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf-C2H2_9 PF16293.5 KKK42565.1 - 6.6 6.7 6.0 23 4.9 0.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-rbx1 PF12678.7 KKK42565.1 - 7.2 7.0 9.5 27 5.1 9.5 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 KKK42565.1 - 8.7 6.3 11.7 2.4 8.0 0.1 3.9 3 1 1 4 4 4 0 Rad50 zinc hook motif 4HFCP_synth PF04476.13 KKK42566.1 - 1.3e-72 244.2 0.0 1.5e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 4-HFC-P synthase QRPTase_C PF01729.19 KKK42566.1 - 2.9e-05 23.9 0.1 0.00034 20.4 0.1 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain P5CR_dimer PF14748.6 KKK42567.1 - 7.3e-39 132.2 0.4 1.3e-38 131.4 0.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KKK42567.1 - 3.3e-13 50.0 2.6 5.1e-13 49.4 1.5 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KKK42567.1 - 5.1e-06 26.7 0.5 9e-06 25.9 0.4 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 KKK42567.1 - 0.00053 19.1 1.7 0.0018 17.3 1.7 1.8 1 1 0 1 1 1 1 Prephenate dehydrogenase Sacchrp_dh_NADP PF03435.18 KKK42567.1 - 0.0011 19.2 0.4 0.0019 18.5 0.4 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 KKK42567.1 - 0.0013 18.1 0.1 0.0023 17.3 0.1 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KKK42567.1 - 0.0023 17.9 4.2 0.0078 16.2 4.2 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FGGY_N PF00370.21 KKK42567.1 - 0.019 14.5 2.1 0.04 13.5 2.1 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain GFO_IDH_MocA PF01408.22 KKK42567.1 - 0.021 15.6 0.1 0.052 14.4 0.1 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KKK42567.1 - 0.12 13.1 0.6 0.23 12.1 0.6 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GHMP_kinases_N PF00288.26 KKK42568.1 - 5.3e-06 26.6 0.1 1.2e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK42568.1 - 0.00051 20.4 0.1 0.0079 16.5 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal POTRA_3 PF17287.2 KKK42568.1 - 0.086 12.3 1.1 0.21 11.1 1.1 1.6 1 0 0 1 1 1 0 POTRA domain AA_kinase PF00696.28 KKK42569.1 - 9.8e-28 97.4 1.7 3e-27 95.8 1.7 1.7 1 1 0 1 1 1 1 Amino acid kinase family Ribosomal_L36 PF00444.18 KKK42569.1 - 0.31 11.3 2.1 0.72 10.1 2.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L36 DUF2116 PF09889.9 KKK42570.1 - 7.4e-17 61.1 2.2 9.8e-17 60.7 2.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) PLATZ PF04640.14 KKK42570.1 - 0.0021 18.6 2.0 0.0021 18.6 2.0 1.4 2 0 0 2 2 2 1 PLATZ transcription factor DUF2615 PF11027.8 KKK42570.1 - 0.0043 17.2 0.0 0.0054 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) SNARE PF05739.19 KKK42570.1 - 0.14 12.2 0.8 0.21 11.6 0.8 1.3 1 0 0 1 1 1 0 SNARE domain zf-C6H2 PF15801.5 KKK42570.1 - 0.36 11.2 8.2 0.29 11.5 6.7 1.7 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-H2C2_2 PF13465.6 KKK42570.1 - 0.41 11.2 0.2 0.41 11.2 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger double domain DUF2256 PF10013.9 KKK42570.1 - 2 8.6 9.8 75 3.6 8.5 2.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Profilin PF00235.19 KKK42573.1 - 0.0042 17.4 0.3 0.0083 16.4 0.1 1.6 1 1 1 2 2 2 1 Profilin TFIIB PF00382.19 KKK42574.1 - 4.5e-35 119.5 0.8 3.8e-18 65.3 0.3 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KKK42574.1 - 1.7e-16 59.4 0.7 3.5e-16 58.4 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KKK42574.1 - 9.2e-07 28.7 0.0 0.00047 19.9 0.1 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain HTH_AsnC-type PF13404.6 KKK42574.1 - 0.00061 19.6 0.3 0.0015 18.3 0.3 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain RB_B PF01857.20 KKK42574.1 - 0.0041 17.2 0.1 0.0099 15.9 0.1 1.6 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Ribosomal_S27e PF01667.17 KKK42574.1 - 0.0042 16.7 0.2 0.0078 15.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 A2L_zn_ribbon PF08792.10 KKK42574.1 - 0.011 15.5 3.4 0.019 14.7 3.4 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain HTH_24 PF13412.6 KKK42574.1 - 0.012 15.2 0.1 0.031 13.9 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 KKK42574.1 - 0.013 15.0 0.2 0.036 13.6 0.2 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 RPA_interact_C PF14768.6 KKK42574.1 - 0.018 15.6 0.0 0.035 14.7 0.0 1.6 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Lar_restr_allev PF14354.6 KKK42574.1 - 0.05 14.0 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar Cyclin_C PF02984.19 KKK42574.1 - 0.11 12.6 0.0 18 5.5 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain zf-ribbon_3 PF13248.6 KKK42574.1 - 0.29 10.6 2.7 1.6 8.3 2.7 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KKK42575.1 - 2.5e-09 36.7 5.2 5.1e-09 35.7 5.2 1.5 1 1 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 KKK42575.1 - 0.0098 15.6 1.1 1.6 8.5 0.2 2.2 2 0 0 2 2 2 2 zinc-ribbon domain zf_UBZ PF18439.1 KKK42575.1 - 0.094 12.3 1.9 4.7 6.9 0.1 2.3 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KKK42575.1 - 1.9 8.7 8.5 10 6.3 1.3 3.0 3 1 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain PAC2 PF09754.9 KKK42576.1 - 7.2e-24 85.0 0.0 8.8e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Invas_SpaK PF03519.14 KKK42576.1 - 0.092 12.8 0.1 5.1 7.2 0.1 2.7 2 0 0 2 2 2 0 Invasion protein B family CxxCxxCC PF03692.15 KKK42577.1 - 2.1e-06 28.3 2.3 3.4e-06 27.6 1.6 1.8 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF3109 PF11307.8 KKK42577.1 - 0.0008 19.3 0.8 0.00098 19.0 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) SWIM PF04434.17 KKK42578.1 - 0.00023 20.8 0.3 0.00046 19.8 0.3 1.4 1 0 0 1 1 1 1 SWIM zinc finger Glycos_transf_1 PF00534.20 KKK42579.1 - 5e-26 91.3 0.4 1e-25 90.3 0.4 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK42579.1 - 2.6e-19 70.0 0.0 4.7e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK42579.1 - 1.9e-12 47.5 0.0 1.1e-11 45.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KKK42579.1 - 2.8e-12 46.9 0.0 4.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Orn_Arg_deC_N PF02784.16 KKK42580.1 - 3e-27 95.6 0.2 4.1e-27 95.1 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ala_racemase_N PF01168.20 KKK42580.1 - 2.8e-07 30.4 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Orn_DAP_Arg_deC PF00278.22 KKK42580.1 - 0.00053 20.2 0.0 0.00065 19.9 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Tubulin PF00091.25 KKK42581.1 - 1.4e-37 129.9 1.7 3.6e-37 128.5 1.7 1.7 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 KKK42581.1 - 1.9e-29 101.8 2.1 4.1e-29 100.7 1.1 2.1 2 0 0 2 2 2 1 FtsZ family, C-terminal domain KH_2 PF07650.17 KKK42582.1 - 5.4e-06 26.1 2.2 0.026 14.3 0.1 2.9 2 1 1 3 3 3 2 KH domain KH_1 PF00013.29 KKK42582.1 - 6.4e-06 25.9 9.5 0.00035 20.3 0.3 3.1 2 1 1 3 3 3 2 KH domain KH_4 PF13083.6 KKK42582.1 - 0.00021 21.1 2.8 0.0017 18.2 0.1 2.5 2 1 0 2 2 2 1 KH domain RIO1 PF01163.22 KKK42583.1 - 4e-59 199.4 0.1 5.7e-59 198.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KKK42583.1 - 6.2e-05 22.5 0.1 0.00018 20.9 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KKK42583.1 - 0.0028 17.6 0.0 0.1 12.5 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK42583.1 - 0.018 13.9 0.1 0.018 13.9 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2461 PF09365.10 KKK42583.1 - 0.083 12.8 1.8 0.31 11.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) NMD3 PF04981.13 KKK42584.1 - 7.3e-38 130.4 0.3 9.1e-38 130.1 0.3 1.1 1 0 0 1 1 1 1 NMD3 family zf-C4pol PF14260.6 KKK42584.1 - 0.024 15.1 2.2 3.3 8.3 0.1 2.8 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta ArfGap PF01412.18 KKK42584.1 - 0.14 12.2 4.4 1.5 8.9 2.0 2.5 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.7 KKK42584.1 - 0.28 11.3 6.9 1.6 8.8 4.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 KKK42584.1 - 0.37 10.9 2.0 3.7 7.8 1.0 2.4 2 1 0 2 2 2 0 FYVE zinc finger DUF424 PF04242.13 KKK42585.1 - 3.6e-16 59.2 0.1 4.2e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF424) eIF-5_eIF-2B PF01873.17 KKK42586.1 - 3e-29 101.3 0.8 3.6e-29 101.0 0.8 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.6 KKK42586.1 - 0.051 13.6 0.4 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon Lar_restr_allev PF14354.6 KKK42586.1 - 0.09 13.2 0.5 0.15 12.5 0.5 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-CCHC_2 PF13696.6 KKK42586.1 - 0.41 10.5 1.9 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle tRNA_anti-codon PF01336.25 KKK42587.1 - 8.4e-05 22.5 0.1 0.00026 20.9 0.1 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KKK42587.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 RPA_C PF08784.11 KKK42587.1 - 0.17 12.6 0.0 0.25 12.0 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal Peptidase_M50 PF02163.22 KKK42588.1 - 3.7e-17 62.4 0.0 9.9e-17 61.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M50 PDZ_1 PF12812.7 KKK42588.1 - 0.042 13.9 0.1 0.15 12.1 0.1 1.9 1 0 0 1 1 1 0 PDZ-like domain ASC PF00858.24 KKK42588.1 - 0.21 10.5 1.4 0.47 9.4 1.4 1.5 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel TMEM18 PF14770.6 KKK42588.1 - 0.56 10.2 7.7 1.5 8.8 7.7 1.7 1 0 0 1 1 1 0 Transmembrane protein 18 E1-E2_ATPase PF00122.20 KKK42588.1 - 3.6 7.1 4.3 2 7.9 1.6 2.0 1 1 1 2 2 2 0 E1-E2 ATPase ATP_bind_3 PF01171.20 KKK42589.1 - 6.1e-15 55.4 0.0 1.2e-14 54.5 0.0 1.5 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 KKK42589.1 - 0.00024 20.0 0.0 0.00031 19.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KKK42589.1 - 0.00055 19.1 0.0 0.00079 18.6 0.0 1.2 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 KKK42589.1 - 0.0021 17.6 0.0 0.006 16.1 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC zn-ribbon_14 PF16503.5 KKK42589.1 - 4.5 6.9 15.8 0.054 13.0 3.8 3.0 3 0 0 3 3 3 0 Zinc-ribbon ArsA_ATPase PF02374.15 KKK42590.1 - 8.4e-85 284.6 0.2 9.7e-85 284.4 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KKK42590.1 - 9.1e-10 38.7 0.1 6.4e-09 36.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 KKK42590.1 - 1.5e-08 34.8 0.0 2.9e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KKK42590.1 - 7.3e-05 22.3 6.2 0.0078 15.7 0.2 3.1 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase PhoH PF02562.16 KKK42590.1 - 0.00026 20.5 0.0 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein SRP54 PF00448.22 KKK42590.1 - 0.0012 18.6 0.0 0.026 14.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KKK42590.1 - 0.017 14.9 0.2 0.094 12.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KKK42590.1 - 0.028 13.9 0.0 0.072 12.5 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 KKK42590.1 - 2.1 8.2 5.0 5 7.0 0.2 2.2 2 0 0 2 2 2 0 RsgA GTPase eRF1_2 PF03464.15 KKK42591.1 - 3.9e-32 111.3 0.5 8.4e-32 110.3 0.2 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 KKK42591.1 - 1.2e-29 103.1 1.1 3.5e-29 101.6 1.1 1.9 1 0 0 1 1 1 1 eRF1 domain 3 acVLRF1 PF18859.1 KKK42591.1 - 4.5e-15 56.1 0.0 7.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KKK42591.1 - 4.8e-13 49.5 0.0 7.8e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 eRF1_1 PF03463.15 KKK42591.1 - 1.7e-07 31.3 0.2 3.8e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 1 FdhE PF04216.12 KKK42591.1 - 0.0033 17.4 0.2 0.0054 16.7 0.2 1.2 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation DUF1340 PF07067.11 KKK42591.1 - 0.0044 16.4 0.6 0.0089 15.4 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1340) HypA PF01155.19 KKK42591.1 - 0.018 15.1 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA baeRF_family5 PF18846.1 KKK42591.1 - 0.1 12.8 2.8 0.43 10.8 0.0 3.2 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 5 PPS_PS PF02006.16 KKK42592.1 - 2.1e-63 213.1 5.7 2.6e-63 212.8 5.7 1.1 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase RTT107_BRCT_6 PF16771.5 KKK42592.1 - 0.0051 16.9 1.5 0.0081 16.3 0.1 1.9 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain NMO PF03060.15 KKK42592.1 - 0.085 12.2 0.2 0.2 11.0 0.0 1.6 1 1 1 2 2 2 0 Nitronate monooxygenase Acetyltransf_1 PF00583.25 KKK42593.1 - 2.1e-14 53.8 0.0 2.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK42593.1 - 2.1e-13 50.3 0.1 2.8e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK42593.1 - 7.6e-11 42.3 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK42593.1 - 4.9e-06 26.4 0.0 6.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KKK42593.1 - 5.7e-05 23.3 1.7 8e-05 22.8 1.7 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KKK42593.1 - 0.00023 20.7 3.2 0.00031 20.3 3.2 1.5 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KKK42593.1 - 0.00091 19.3 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain ApbA_C PF08546.11 KKK42594.1 - 3.1e-32 111.4 0.2 5.2e-32 110.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKK42594.1 - 2.7e-29 101.8 0.0 4.2e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SLIDE PF09111.10 KKK42594.1 - 0.031 14.3 1.8 0.053 13.6 0.1 2.2 2 1 0 2 2 2 0 SLIDE NAD_Gly3P_dh_N PF01210.23 KKK42594.1 - 0.061 13.3 0.1 0.35 10.8 0.0 2.4 3 1 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Flag1_repress PF03614.13 KKK42594.1 - 0.091 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Methyltransf_3 PF01596.17 KKK42594.1 - 0.25 10.5 3.6 0.11 11.6 0.6 1.9 2 1 0 2 2 2 0 O-methyltransferase DUF72 PF01904.18 KKK42595.1 - 1.6e-55 188.6 0.4 1.8e-55 188.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 Phg_2220_C PF09524.10 KKK42595.1 - 0.0029 17.6 0.3 0.0076 16.3 0.3 1.7 1 0 0 1 1 1 1 Conserved phage C-terminus (Phg_2220_C) DHDPS PF00701.22 KKK42595.1 - 0.12 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family ABC_sub_bind PF04392.12 KKK42595.1 - 0.27 10.5 0.2 0.36 10.0 0.2 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein RMMBL PF07521.12 KKK42601.1 - 1.1e-06 28.5 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Flavin_Reduct PF01613.18 KKK42602.1 - 4.6e-21 75.5 0.0 5.5e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain fn3_PAP PF17808.1 KKK42602.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Fer4 PF00037.27 KKK42603.1 - 5.4e-10 38.7 12.0 4.3e-06 26.3 1.1 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK42603.1 - 3.9e-09 36.2 13.1 0.00019 21.4 1.2 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK42603.1 - 6e-08 33.5 12.3 0.00051 20.9 0.3 3.7 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK42603.1 - 2.3e-07 31.3 11.6 2.3e-07 31.3 11.6 2.3 1 1 2 3 3 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK42603.1 - 1.1e-06 28.7 18.6 0.003 17.7 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK42603.1 - 1e-05 25.6 8.3 1e-05 25.6 8.3 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK42603.1 - 0.00018 21.6 23.7 0.00058 19.9 13.7 2.8 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK42603.1 - 0.0012 18.8 11.5 0.002 18.1 2.4 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KKK42603.1 - 0.0071 16.8 1.6 0.0071 16.8 1.6 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK42603.1 - 0.021 15.4 21.3 0.25 11.9 4.7 3.5 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK42603.1 - 0.025 15.0 0.4 0.025 15.0 0.4 3.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain HTH_35 PF13693.6 KKK42603.1 - 0.039 14.0 0.0 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Fer4_15 PF13459.6 KKK42603.1 - 0.7 10.7 9.4 0.3 11.8 0.6 2.9 3 0 0 3 3 2 0 4Fe-4S single cluster domain Gelsolin PF00626.22 KKK42604.1 - 0.0034 17.2 0.0 0.0086 16.0 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Ras PF00071.22 KKK42607.1 - 4.2e-37 127.2 0.2 5.7e-37 126.8 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42607.1 - 2.7e-26 92.1 0.1 4e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42607.1 - 1.9e-12 47.0 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42607.1 - 1.5e-07 31.0 0.4 2e-07 30.6 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK42607.1 - 4.3e-05 23.0 0.1 7.8e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKK42607.1 - 0.0003 20.7 0.1 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KKK42607.1 - 0.00047 20.2 0.1 0.00078 19.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK42607.1 - 0.001 18.6 0.2 0.77 9.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B ATPase_2 PF01637.18 KKK42607.1 - 0.011 15.6 0.9 0.022 14.7 0.9 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KKK42607.1 - 0.018 15.0 0.2 0.044 13.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KKK42607.1 - 0.022 14.2 0.0 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 KKK42607.1 - 0.024 15.1 0.1 1.5 9.2 0.0 2.7 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KKK42607.1 - 0.026 14.0 0.1 0.058 12.9 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KKK42607.1 - 0.068 12.9 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KKK42607.1 - 0.069 13.1 0.2 0.12 12.2 0.2 1.7 1 1 0 1 1 1 0 NTPase CTP_transf_3 PF02348.19 KKK42607.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase AAA_16 PF13191.6 KKK42607.1 - 0.18 12.2 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KKK42607.1 - 0.18 12.0 0.0 0.68 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Vps51 PF08700.11 KKK42608.1 - 0.076 13.1 0.8 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Vps51/Vps67 Ras PF00071.22 KKK42609.1 - 2.8e-38 131.1 1.7 4.4e-38 130.4 1.2 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KKK42609.1 - 2.5e-25 89.0 0.3 4.5e-25 88.2 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42609.1 - 3e-13 49.6 0.1 5.5e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42609.1 - 7.1e-07 28.8 0.4 1.3e-06 28.0 0.4 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Robl_LC7 PF03259.17 KKK42609.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain G-alpha PF00503.20 KKK42609.1 - 0.0026 17.0 2.2 0.013 14.7 2.2 2.3 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KKK42609.1 - 0.0045 17.0 0.2 0.01 15.9 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK42609.1 - 0.0061 16.0 2.0 0.054 12.9 0.7 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKK42609.1 - 0.014 15.3 0.6 0.13 12.1 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KKK42609.1 - 0.076 12.9 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 NTPase N6_N4_Mtase PF01555.18 KKK42610.1 - 6.3e-17 62.1 1.1 2.6e-16 60.1 0.0 1.9 1 1 1 2 2 2 1 DNA methylase UPF0020 PF01170.18 KKK42610.1 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 GreA_GreB_N PF03449.15 KKK42616.1 - 0.028 14.6 0.9 0.031 14.4 0.9 1.2 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal adh_short_C2 PF13561.6 KKK42617.1 - 4e-54 183.6 0.0 5.2e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK42617.1 - 3.8e-41 140.7 0.0 5.6e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK42617.1 - 2.8e-07 30.6 0.0 7.1e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KKK42617.1 - 0.0098 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KKK42617.1 - 0.038 13.4 0.1 0.15 11.5 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KKK42617.1 - 0.091 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KKK42617.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.16 KKK42618.1 - 2.7e-34 118.6 60.6 4.4e-32 111.4 45.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK42618.1 - 0.00016 20.3 43.1 0.00034 19.3 15.1 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein Ost5 PF05251.12 KKK42618.1 - 0.012 15.8 2.6 0.012 15.8 2.6 4.9 4 1 1 5 5 5 0 Oligosaccharyltransferase subunit 5 NDUF_B5 PF09781.9 KKK42618.1 - 0.16 11.6 0.2 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Hemocyanin_M PF00372.19 KKK42619.1 - 0.049 12.8 0.3 0.062 12.5 0.3 1.2 1 0 0 1 1 1 0 Hemocyanin, copper containing domain BacA PF02673.18 KKK42619.1 - 0.13 12.0 5.8 0.8 9.4 5.9 1.9 1 1 0 1 1 1 0 Bacitracin resistance protein BacA DUF1634 PF07843.11 KKK42619.1 - 0.13 12.3 6.1 1.3 9.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1634) Acyl_transf_3 PF01757.22 KKK42619.1 - 0.24 10.4 10.5 1.2 8.1 9.6 1.9 1 1 1 2 2 2 0 Acyltransferase family DUF3290 PF11694.8 KKK42619.1 - 0.42 10.6 5.2 0.34 10.9 2.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4131 PF13567.6 KKK42619.1 - 0.51 10.0 2.4 2.5 7.7 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) AA_permease_2 PF13520.6 KKK42619.1 - 0.72 8.6 12.4 2.2 7.0 12.5 1.7 1 1 0 1 1 1 0 Amino acid permease DUF2116 PF09889.9 KKK42619.1 - 0.83 9.7 4.3 4.2 7.4 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PALP PF00291.25 KKK42622.1 - 1.1e-14 54.6 0.0 1.2e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 KKK42623.1 - 1e-28 100.7 0.1 1.1e-28 100.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TPR_2 PF07719.17 KKK42630.1 - 0.036 14.2 1.5 1.1 9.6 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK42630.1 - 0.046 13.9 4.0 0.44 10.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK42630.1 - 0.3 11.0 2.0 0.78 9.7 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4431 PF14485.6 KKK42631.1 - 0.12 12.2 0.0 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) KH_7 PF17214.3 KKK42631.1 - 0.14 12.1 0.1 0.61 10.1 0.1 1.9 1 1 1 2 2 2 0 KH domain Pantoate_transf PF02548.15 KKK42632.1 - 7.1e-106 353.3 0.5 8.1e-106 353.2 0.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KKK42632.1 - 0.0085 15.6 0.0 0.017 14.6 0.0 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Methyltransf_11 PF08241.12 KKK42633.1 - 4.6e-23 81.7 0.0 6.6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK42633.1 - 2.9e-19 69.6 0.0 4.3e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK42633.1 - 4.3e-16 59.0 0.0 6.3e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK42633.1 - 2.2e-12 46.8 0.0 2.6e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KKK42633.1 - 3e-12 46.7 0.0 3.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK42633.1 - 3e-10 40.7 0.0 4.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KKK42633.1 - 8.9e-08 31.8 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.15 KKK42633.1 - 9.4e-05 22.4 0.0 0.00051 20.0 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KKK42633.1 - 0.00034 20.2 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KKK42633.1 - 0.00099 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 KKK42633.1 - 0.0047 16.3 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KKK42633.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TPMT PF05724.11 KKK42633.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KKK42633.1 - 0.029 14.4 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KKK42633.1 - 0.074 12.1 0.0 0.092 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 KKK42633.1 - 0.081 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KKK42633.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KKK42633.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 KKK42633.1 - 0.2 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TusA PF01206.17 KKK42635.1 - 7e-19 67.4 0.1 7.6e-19 67.3 0.1 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DrsE PF02635.15 KKK42636.1 - 8.1e-24 84.3 0.0 1.3e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 KKK42636.1 - 0.00012 22.0 1.7 0.00019 21.4 1.7 1.5 1 1 0 1 1 1 1 DsrE/DsrF/DrsH-like family DsrH PF04077.12 KKK42636.1 - 0.0012 18.9 0.0 0.006 16.7 0.0 2.1 1 1 0 1 1 1 1 DsrH like protein PAR1 PF06521.11 KKK42636.1 - 0.01 15.5 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 PAR1 protein LysR_substrate PF03466.20 KKK42637.1 - 2.1e-23 82.8 0.0 2.8e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 KKK42637.1 - 3.8e-11 42.7 0.0 6.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Mga PF05043.13 KKK42637.1 - 0.0011 19.5 3.8 0.0021 18.6 0.9 2.8 3 0 0 3 3 3 1 Mga helix-turn-helix domain HTH_5 PF01022.20 KKK42637.1 - 0.0027 17.6 0.1 0.0065 16.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family PBP_like_2 PF12849.7 KKK42637.1 - 0.01 15.6 0.0 0.52 9.9 0.0 2.4 2 1 0 2 2 2 0 PBP superfamily domain HTH_50 PF18024.1 KKK42637.1 - 0.011 15.4 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PBP_like PF12727.7 KKK42637.1 - 0.016 14.3 0.0 0.25 10.4 0.0 2.2 1 1 0 1 1 1 0 PBP superfamily domain BAR_3 PF16746.5 KKK42637.1 - 0.049 13.3 0.6 0.049 13.3 0.6 1.9 2 0 0 2 2 2 0 BAR domain of APPL family HTH_10 PF04967.12 KKK42637.1 - 0.15 11.9 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain ALIX_LYPXL_bnd PF13949.6 KKK42638.1 - 0.27 10.5 5.4 0.4 9.9 5.4 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV OppC_N PF12911.7 KKK42638.1 - 1.5 8.9 4.3 16 5.6 0.7 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C SMN PF06003.12 KKK42638.1 - 9.6 5.4 7.7 4 6.6 5.1 1.6 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) DUF2157 PF09925.9 KKK42639.1 - 0.071 12.9 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) CoA_binding_2 PF13380.6 KKK42640.1 - 5e-08 33.4 0.0 1.3e-07 32.1 0.0 1.6 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 KKK42640.1 - 0.0012 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain MOZART2 PF12926.7 KKK42640.1 - 0.026 14.1 0.2 0.043 13.4 0.2 1.3 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated CoA_binding PF02629.19 KKK42640.1 - 0.043 14.5 0.0 0.064 13.9 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain Helicase_C PF00271.31 KKK42646.1 - 2.9e-22 79.1 0.3 2.9e-22 79.1 0.3 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK42646.1 - 7.3e-20 71.7 4.6 7.8e-20 71.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK42646.1 - 1.6e-18 67.1 0.1 4.9e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC4 PF02732.15 KKK42646.1 - 2.6e-18 66.7 0.0 2.6e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain HHH_2 PF12826.7 KKK42646.1 - 2.4e-08 34.0 0.1 2.1e-07 30.9 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KKK42646.1 - 4.2e-07 30.5 2.7 7.8e-07 29.6 0.1 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain SWI2_SNF2 PF18766.1 KKK42646.1 - 1.1e-05 25.3 0.5 3.2e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 SWI2/SNF2 ATPase HHH PF00633.23 KKK42646.1 - 0.0059 16.4 0.1 0.021 14.7 0.0 2.1 2 0 0 2 2 1 1 Helix-hairpin-helix motif PhoH PF02562.16 KKK42646.1 - 0.0073 15.8 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein PND PF17949.1 KKK42646.1 - 0.032 14.5 0.0 0.1 12.9 0.0 1.9 1 0 0 1 1 1 0 FANCM pseudonuclease domain 5_3_exonuc PF01367.20 KKK42646.1 - 0.034 14.7 0.1 0.034 14.7 0.1 3.8 5 0 0 5 5 4 0 5'-3' exonuclease, C-terminal SAM fold RNA_pol_A_CTD PF03118.15 KKK42646.1 - 0.062 13.1 0.1 0.062 13.1 0.1 3.1 3 0 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain HHH_8 PF14716.6 KKK42646.1 - 0.097 13.0 0.2 0.77 10.2 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_3 PF12836.7 KKK42646.1 - 0.93 9.8 4.2 7.2 7.0 0.0 3.5 3 1 1 4 4 3 0 Helix-hairpin-helix motif Ras PF00071.22 KKK42647.1 - 9.8e-43 145.6 0.3 1.1e-42 145.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42647.1 - 9.9e-27 93.5 0.0 1.5e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42647.1 - 1.6e-13 50.5 0.1 2.1e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK42647.1 - 1.1e-05 25.4 0.2 2.2e-05 24.5 0.1 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK42647.1 - 6.4e-05 22.5 0.2 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DZR PF12773.7 KKK42647.1 - 0.00015 21.7 0.2 0.00022 21.2 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK42647.1 - 0.0036 18.0 0.2 0.005 17.5 0.2 1.3 1 0 0 1 1 1 1 zinc-ribbon family Gtr1_RagA PF04670.12 KKK42647.1 - 0.0036 16.7 0.1 0.0049 16.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Methyltransf_13 PF08421.11 KKK42647.1 - 0.0037 17.5 0.1 0.0066 16.7 0.1 1.3 1 0 0 1 1 1 1 Putative zinc binding domain FeoB_N PF02421.18 KKK42647.1 - 0.0042 16.6 0.1 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B UPF0547 PF10571.9 KKK42647.1 - 0.0042 17.1 1.6 0.0083 16.2 1.6 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 KKK42647.1 - 0.0087 15.7 4.1 0.021 14.5 4.1 1.7 1 0 0 1 1 1 1 zinc-ribbon domain AAA_14 PF13173.6 KKK42647.1 - 0.015 15.4 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain NOB1_Zn_bind PF08772.11 KKK42647.1 - 0.035 14.3 0.9 0.069 13.3 0.9 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like AAA_22 PF13401.6 KKK42647.1 - 0.082 13.2 0.0 0.37 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF35_N PF12172.8 KKK42647.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) AAA_24 PF13479.6 KKK42647.1 - 0.13 12.0 1.2 0.19 11.4 0.1 1.8 2 1 0 2 2 2 0 AAA domain zf-ribbon_3 PF13248.6 KKK42647.1 - 0.13 11.7 4.1 0.3 10.5 4.1 1.7 1 1 0 1 1 1 0 zinc-ribbon domain RsgA_GTPase PF03193.16 KKK42647.1 - 0.14 12.0 0.5 16 5.4 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase GDP_Man_Dehyd PF16363.5 KKK42648.1 - 3.7e-46 158.0 0.0 8.2e-46 156.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK42648.1 - 2.5e-44 151.6 0.0 4.9e-44 150.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KKK42648.1 - 4.2e-10 39.2 0.0 2.5e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KKK42648.1 - 9.8e-10 37.9 0.0 3.8e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KKK42648.1 - 1.9e-08 33.8 0.0 0.0047 16.1 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KKK42648.1 - 8.9e-07 28.3 0.0 1.2e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KKK42648.1 - 0.00072 19.1 0.0 0.0074 15.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK42648.1 - 0.047 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 KR domain DUF1616 PF07760.11 KKK42649.1 - 1.4e-12 47.6 0.0 1.7e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) PmbA_TldD PF01523.16 KKK42650.1 - 1.3e-39 136.8 0.0 1.9e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 KKK42651.1 - 1.5e-48 166.0 0.0 2.1e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase DUF2498 PF10692.9 KKK42651.1 - 0.016 15.1 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Methyltransf_11 PF08241.12 KKK42652.1 - 8.6e-07 29.5 0.0 1.5e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK42652.1 - 1.8e-05 25.3 0.0 3.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK42652.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK42652.1 - 0.0029 17.4 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK42652.1 - 0.0052 15.8 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KKK42652.1 - 0.028 15.2 0.0 0.054 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KKK42652.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Lyase_1 PF00206.20 KKK42653.1 - 2.1e-44 152.2 0.3 3.1e-44 151.6 0.3 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KKK42653.1 - 3.2e-17 62.9 0.4 1.6e-16 60.6 0.0 2.4 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus FumaraseC_C PF10415.9 KKK42653.1 - 0.0062 16.9 0.8 2.1 8.8 0.0 3.8 3 1 1 4 4 4 1 Fumarase C C-terminus Ribosomal_S13 PF00416.22 KKK42653.1 - 0.032 14.6 1.2 0.37 11.2 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein S13/S18 AIRS_C PF02769.22 KKK42654.1 - 2.9e-05 24.3 0.1 0.00049 20.2 0.1 2.5 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain LAGLIDADG_WhiA PF14527.6 KKK42654.1 - 0.11 12.6 0.2 0.44 10.6 0.3 2.0 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain PfkB PF00294.24 KKK42655.1 - 6.5e-50 170.1 0.2 7.5e-50 169.9 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CPBP PF02517.16 KKK42656.1 - 1.6e-10 41.2 9.9 1.6e-10 41.2 9.9 3.8 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Metallophos_2 PF12850.7 KKK42657.1 - 6.4e-17 62.2 0.0 9.3e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KKK42657.1 - 2.1e-05 25.2 0.3 0.00047 20.7 0.0 2.0 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase AFOR_C PF01314.18 KKK42659.1 - 2e-26 92.9 0.0 2.2e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Fer4_11 PF13247.6 KKK42660.1 - 1.8e-10 40.8 11.0 1.8e-10 40.8 11.0 1.8 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK42660.1 - 9.5e-10 38.5 14.4 0.00015 21.9 1.6 3.1 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK42660.1 - 5.9e-09 36.4 21.0 6.3e-05 23.5 10.8 3.6 2 1 0 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK42660.1 - 1.6e-06 27.9 38.3 0.00025 21.0 3.5 5.6 6 0 0 6 6 6 3 4Fe-4S binding domain Fer4 PF00037.27 KKK42660.1 - 0.00036 20.2 3.8 0.00036 20.2 3.8 5.7 7 0 0 7 7 6 4 4Fe-4S binding domain Fer4_10 PF13237.6 KKK42660.1 - 0.0011 19.0 25.3 0.044 13.9 13.2 3.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK42660.1 - 0.0015 18.5 31.7 0.032 14.3 3.4 4.9 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_3 PF12798.7 KKK42660.1 - 0.0054 17.6 30.8 0.46 11.5 4.7 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_4 PF12800.7 KKK42660.1 - 0.016 15.7 30.7 0.46 11.1 3.8 4.8 5 1 0 5 5 4 0 4Fe-4S binding domain Ta0938 PF11494.8 KKK42660.1 - 0.024 14.9 2.0 0.029 14.7 0.0 2.1 1 1 0 2 2 2 0 Ta0938 Fer4_16 PF13484.6 KKK42660.1 - 0.063 14.2 28.4 0.22 12.5 0.0 4.6 3 2 0 4 4 4 0 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 KKK42660.1 - 5.2 7.9 21.0 0.73 10.6 7.9 3.7 3 2 0 3 3 3 0 4Fe-4S single cluster domain Fer4_21 PF14697.6 KKK42660.1 - 8.9 6.5 29.4 0.048 13.8 11.1 4.3 3 2 1 4 4 4 0 4Fe-4S dicluster domain DUF4276 PF14103.6 KKK42661.1 - 6.1e-07 29.8 1.3 2.1e-06 28.1 1.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4276) DUF4435 PF14491.6 KKK42661.1 - 0.0023 17.9 6.9 0.0023 17.9 6.9 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF4435) DUF5109 PF17134.4 KKK42661.1 - 0.011 15.6 0.3 0.019 14.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) SRI PF08236.11 KKK42661.1 - 0.013 15.7 3.4 0.013 15.7 3.4 2.3 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain TUDOR PF00567.24 KKK42661.1 - 0.027 14.5 0.2 0.08 13.0 0.1 1.8 1 1 1 2 2 2 0 Tudor domain MutS_I PF01624.20 KKK42661.1 - 0.09 13.0 0.8 0.37 11.1 0.3 2.1 1 1 0 2 2 2 0 MutS domain I DUF1829 PF08862.10 KKK42661.1 - 0.77 10.3 5.1 1.3 9.6 0.1 3.2 2 1 2 4 4 4 0 Domain of unknown function DUF1829 AAA_21 PF13304.6 KKK42662.1 - 3.1e-29 102.8 13.2 2e-27 96.8 13.2 2.3 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKK42662.1 - 4.7e-27 95.7 30.5 1.1e-26 94.5 30.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KKK42662.1 - 4.3e-15 55.7 0.0 1.6e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF2813 PF11398.8 KKK42662.1 - 1.1e-07 31.5 0.2 0.0096 15.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2813) AAA_23 PF13476.6 KKK42662.1 - 1.5e-05 25.6 18.7 3.4e-05 24.4 18.7 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK42662.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KKK42662.1 - 0.073 13.6 0.3 0.79 10.2 0.4 2.5 2 1 0 2 2 2 0 ABC transporter MA3 PF02847.17 KKK42662.1 - 0.074 13.0 0.2 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 MA3 domain DUF5118 PF17162.4 KKK42662.1 - 0.085 12.7 0.7 0.31 10.9 0.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) Ta0938 PF11494.8 KKK42663.1 - 0.0013 19.0 0.0 0.0013 18.9 0.0 1.1 1 0 0 1 1 1 1 Ta0938 Fer4_16 PF13484.6 KKK42663.1 - 0.013 16.4 0.2 0.057 14.3 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK42663.1 - 0.024 15.2 0.8 0.053 14.1 1.0 1.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK42663.1 - 0.077 14.0 0.7 0.12 13.4 0.7 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Beta-lactamase PF00144.24 KKK42665.1 - 8.2e-55 186.3 0.0 9.4e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Oxidored_FMN PF00724.20 KKK42666.1 - 0.018 14.4 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Aminotran_1_2 PF00155.21 KKK42670.1 - 1.7e-40 139.3 0.0 2.1e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK42670.1 - 1e-07 31.3 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 KKK42670.1 - 1.1e-05 24.5 0.0 2e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 KKK42670.1 - 0.0014 17.2 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KKK42670.1 - 0.15 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fer4_5 PF12801.7 KKK42671.1 - 2.5e-14 52.9 23.3 1.6e-10 40.7 3.0 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4 PF00037.27 KKK42671.1 - 3.3e-05 23.5 22.2 0.0052 16.6 2.2 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 KKK42671.1 - 0.0018 18.4 23.4 0.0031 17.6 11.4 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK42671.1 - 0.0039 17.3 10.6 0.0039 17.3 10.6 2.3 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK42671.1 - 0.0045 17.6 17.1 0.052 14.1 12.5 3.2 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK42671.1 - 0.0077 16.3 2.0 0.0077 16.3 2.0 3.3 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK42671.1 - 0.56 11.2 19.8 0.87 10.6 2.1 3.8 3 1 1 4 4 4 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 KKK42671.1 - 1.1 9.5 13.0 13 6.0 10.4 3.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK42671.1 - 1.3 9.7 18.5 1.9e+03 -0.5 18.5 3.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK42671.1 - 7.9 6.7 15.9 10 6.3 11.0 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain AROS PF15684.5 KKK42674.1 - 0.0033 18.0 0.2 0.0047 17.5 0.2 1.3 1 0 0 1 1 1 1 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Amidohydro_2 PF04909.14 KKK42674.1 - 0.042 13.6 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase DUF445 PF04286.12 KKK42675.1 - 0.00092 19.1 3.1 0.001 19.0 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Vps53_N PF04100.12 KKK42675.1 - 0.017 14.1 0.4 0.019 13.9 0.4 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal Duffy_binding PF05424.11 KKK42675.1 - 0.038 14.0 0.7 0.066 13.3 0.7 1.3 1 1 0 1 1 1 0 Duffy binding domain YpjP PF14005.6 KKK42675.1 - 0.14 12.2 4.1 1.2 9.2 1.8 2.0 1 1 1 2 2 2 0 YpjP-like protein Pirin PF02678.16 KKK42676.1 - 4.4e-37 126.3 0.4 2.8e-35 120.5 0.1 2.2 2 0 0 2 2 2 2 Pirin Pirin_C PF05726.13 KKK42676.1 - 1.1e-30 106.1 0.0 9.9e-30 103.0 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KKK42676.1 - 0.073 12.8 0.3 3.4 7.4 0.2 2.3 2 0 0 2 2 2 0 Cupin domain DUF2961 PF11175.8 KKK42677.1 - 1.5e-80 270.3 4.1 1.8e-80 270.0 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) DUF2284 PF10050.9 KKK42683.1 - 1.5e-31 109.3 0.3 2.4e-31 108.7 0.1 1.4 2 0 0 2 2 2 1 Predicted metal-binding protein (DUF2284) B12-binding PF02310.19 KKK42684.1 - 1.8e-19 69.9 0.2 4.4e-19 68.7 0.1 1.7 2 0 0 2 2 2 1 B12 binding domain B12-binding_2 PF02607.17 KKK42684.1 - 0.0021 18.4 0.1 0.013 16.0 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain Fe_dep_repress PF01325.19 KKK42684.1 - 0.12 12.5 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain tRNA_int_endo PF01974.17 KKK42685.1 - 3.8e-28 97.4 0.1 8.7e-28 96.2 0.0 1.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KKK42685.1 - 1.8e-06 27.5 0.0 3.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain RNase_HII PF01351.18 KKK42685.1 - 0.083 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease HII Memo PF01875.17 KKK42686.1 - 1.8e-52 178.2 0.0 2e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LigB PF02900.18 KKK42686.1 - 0.00025 20.2 0.0 0.0084 15.2 0.0 2.0 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase UPF0242 PF06785.11 KKK42687.1 - 5.1e-05 23.5 50.4 0.078 13.1 8.7 4.1 3 1 1 4 4 4 4 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 KKK42687.1 - 0.0056 16.1 5.7 0.0056 16.1 5.7 3.1 1 1 2 3 3 3 1 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 KKK42687.1 - 0.0058 16.8 9.0 0.0058 16.8 9.0 6.5 4 1 1 5 5 4 1 Centrosomin N-terminal motif 1 SBP_bac_3 PF00497.20 KKK42687.1 - 0.0076 15.7 2.1 0.008 15.6 0.5 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Cep57_MT_bd PF06657.13 KKK42687.1 - 0.12 12.8 31.7 0.61 10.6 0.3 6.3 6 2 0 6 6 6 0 Centrosome microtubule-binding domain of Cep57 TRADD_N PF09034.10 KKK42687.1 - 0.15 12.1 11.0 0.13 12.3 2.5 3.0 2 1 0 2 2 2 0 TRADD, N-terminal domain Mto2_bdg PF12808.7 KKK42687.1 - 0.18 12.1 0.2 0.18 12.1 0.2 5.5 6 0 0 6 6 6 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4248 PF14053.6 KKK42687.1 - 2.8 8.0 6.7 0.81 9.8 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4248) DUF1640 PF07798.11 KKK42687.1 - 3.5 7.6 36.7 4.4 7.3 11.8 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF641 PF04859.12 KKK42687.1 - 4 7.8 41.4 1.1 9.5 2.1 5.5 2 1 4 6 6 6 0 Plant protein of unknown function (DUF641) TipAS PF07739.13 KKK42687.1 - 4.6 7.8 10.6 2 9.0 3.1 3.5 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Exonuc_VII_L PF02601.15 KKK42687.1 - 8.8 5.8 28.5 0.16 11.5 12.8 2.5 1 1 0 2 2 2 0 Exonuclease VII, large subunit PfkB PF00294.24 KKK42688.1 - 2.2e-08 33.7 0.0 2.7e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF5383 PF17355.2 KKK42691.1 - 0.059 13.8 0.2 0.059 13.8 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5383) Oxidored_FMN PF00724.20 KKK42694.1 - 3.6e-67 227.0 0.0 5.1e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 KKK42694.1 - 1.7e-17 63.6 6.9 1.5e-12 47.4 2.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KKK42694.1 - 3.1e-06 26.7 0.1 1.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KKK42694.1 - 3.5e-06 26.6 0.0 3.5e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK42694.1 - 5e-06 26.7 0.1 2.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK42694.1 - 6.1e-06 26.7 8.6 3.4e-05 24.3 2.5 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK42694.1 - 2.1e-05 23.9 7.3 0.031 13.5 1.4 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK42694.1 - 7.9e-05 21.9 1.5 0.00012 21.3 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain Dus PF01207.17 KKK42694.1 - 0.00015 20.9 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Thi4 PF01946.17 KKK42694.1 - 0.00021 20.6 0.1 0.00056 19.2 0.1 1.7 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KKK42694.1 - 0.00058 18.7 1.9 0.00058 18.7 1.9 2.0 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KKK42694.1 - 0.00058 19.2 0.3 0.0011 18.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK42694.1 - 0.015 14.9 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KKK42694.1 - 0.046 12.8 2.7 0.07 12.2 0.6 2.1 2 1 0 2 2 2 0 Glucose inhibited division protein A PAC2 PF09754.9 KKK42695.1 - 5.1e-20 72.4 0.0 6.4e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 PAC2 family DZR PF12773.7 KKK42696.1 - 0.0045 17.0 0.1 0.0075 16.3 0.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KKK42696.1 - 0.02 14.8 0.3 2.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_15 PF17032.5 KKK42696.1 - 0.02 15.6 0.0 0.047 14.5 0.0 1.7 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK42696.1 - 0.04 13.3 5.2 1.7 8.1 0.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.9 KKK42696.1 - 0.067 13.3 2.0 0.11 12.6 2.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF35_N PF12172.8 KKK42696.1 - 0.12 12.3 1.7 5.9 6.9 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 KKK42696.1 - 0.14 11.9 8.0 0.71 9.7 8.0 2.0 1 1 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 KKK42696.1 - 0.22 11.7 1.8 8.4 6.6 2.9 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-U1 PF06220.12 KKK42696.1 - 0.83 9.5 2.3 1.5 8.6 2.3 1.4 1 0 0 1 1 1 0 U1 zinc finger DUF2070 PF09843.9 KKK42697.1 - 8.3e-88 295.1 9.1 1e-87 294.8 9.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Tocopherol_cycl PF14249.6 KKK42703.1 - 4.3e-24 85.3 0.5 3.2e-21 75.8 0.0 2.0 1 1 0 2 2 2 2 Tocopherol cyclase Glycos_transf_1 PF00534.20 KKK42705.1 - 6.5e-24 84.4 0.1 1.1e-23 83.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK42705.1 - 7.2e-18 65.3 0.0 1.5e-17 64.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK42705.1 - 1e-08 35.4 0.0 5.8e-08 32.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KKK42705.1 - 6.4e-06 26.5 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_130 PF04041.13 KKK42706.1 - 3.1e-63 213.6 0.0 3.6e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 KKK42706.1 - 1.1e-05 25.1 0.0 0.00034 20.3 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KKK42706.1 - 0.013 14.8 0.0 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 Relaxase PF03432.14 KKK42707.1 - 0.05 13.2 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Med4 PF10018.9 KKK42709.1 - 0.019 14.7 0.4 0.019 14.7 0.4 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 HSDR_N_2 PF13588.6 KKK42710.1 - 0.0093 16.0 0.2 0.016 15.2 0.2 1.4 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) DUF4263 PF14082.6 KKK42710.1 - 0.043 14.1 0.1 0.091 13.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4263) CBFD_NFYB_HMF PF00808.23 KKK42712.1 - 0.0045 17.3 0.0 0.0077 16.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.11 KKK42712.1 - 0.0066 16.6 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1931) Amidase PF01425.21 KKK42714.1 - 1.2e-32 113.5 0.1 1.4e-32 113.2 0.1 1.0 1 0 0 1 1 1 1 Amidase Lactamase_B PF00753.27 KKK42715.1 - 1.1e-12 48.4 0.0 1.2e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK42715.1 - 1.5e-05 24.6 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KKK42715.1 - 0.00012 21.6 0.1 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Arena_ncap_C PF17290.2 KKK42715.1 - 0.055 12.8 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain Amidase PF01425.21 KKK42716.1 - 1.2e-113 380.5 0.0 2.6e-113 379.4 0.0 1.5 1 1 0 1 1 1 1 Amidase DUF1040 PF06288.13 KKK42718.1 - 0.04 14.3 0.0 0.047 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) HTH_24 PF13412.6 KKK42719.1 - 1.4e-05 24.6 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding ERM PF00769.19 KKK42720.1 - 0.00025 21.0 22.2 0.00032 20.6 22.2 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Rrf2 PF02082.20 KKK42720.1 - 0.013 15.8 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 KKK42720.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 MarR family Spc7 PF08317.11 KKK42720.1 - 0.49 9.2 19.7 0.71 8.7 19.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 KKK42720.1 - 0.52 10.1 25.2 1.3 8.8 25.2 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 KKK42720.1 - 0.98 9.2 18.7 1.6 8.5 18.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) zf-C4H2 PF10146.9 KKK42720.1 - 1.5 9.1 17.9 3 8.1 17.5 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein DUF874 PF05917.11 KKK42720.1 - 1.8 7.5 16.2 4 6.4 16.3 1.5 1 1 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF3450 PF11932.8 KKK42720.1 - 2 7.7 14.3 4.8 6.4 14.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 KKK42720.1 - 2 7.4 9.0 2.6 7.1 9.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KKK42720.1 - 2.7 8.5 32.9 1.2 9.7 29.0 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 KKK42720.1 - 3.2 8.5 18.5 2.2 8.9 5.6 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF4164 PF13747.6 KKK42720.1 - 5.3 7.4 16.6 15 5.9 7.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) MFS_1 PF07690.16 KKK42721.1 - 3e-13 49.5 10.1 3.7e-13 49.2 10.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ycf66_N PF07444.11 KKK42721.1 - 0.011 15.8 1.4 0.021 14.9 0.3 2.1 2 0 0 2 2 2 0 Ycf66 protein N-terminus CTP_synth_N PF06418.14 KKK42723.1 - 1.6e-31 109.6 0.1 1.7e-31 109.5 0.1 1.0 1 0 0 1 1 1 1 CTP synthase N-terminus cobW PF02492.19 KKK42723.1 - 0.091 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Enolase_N PF03952.16 KKK42723.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Enolase, N-terminal domain ECH_1 PF00378.20 KKK42724.1 - 2.1e-43 148.4 0.0 2.5e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK42724.1 - 7.8e-14 51.9 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LBP_M PF17385.2 KKK42724.1 - 0.089 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain ADH_N PF08240.12 KKK42725.1 - 8.8e-27 93.1 2.3 1.8e-26 92.2 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK42725.1 - 6.8e-23 81.1 0.0 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK42725.1 - 4.7e-13 49.1 0.0 6.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK42725.1 - 5.3e-05 24.3 0.0 8.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPP_enzyme_C PF02775.21 KKK42726.1 - 7.1e-30 103.8 0.1 9.7e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain G_glu_transpept PF01019.21 KKK42730.1 - 6.8e-39 134.0 0.1 7.7e-39 133.8 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Radical_SAM PF04055.21 KKK42731.1 - 6.1e-18 65.8 0.0 8.7e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily PALP PF00291.25 KKK42733.1 - 8.4e-09 35.2 0.0 9.1e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DrsE PF02635.15 KKK42734.1 - 1.5e-06 28.6 0.0 1.7e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE_2 PF13686.6 KKK42734.1 - 0.00028 20.8 0.0 0.00028 20.8 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF/DrsH-like family DUF5432 PF17497.2 KKK42734.1 - 0.13 12.3 0.3 0.44 10.7 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5432) DUF5572 PF17733.1 KKK42738.1 - 0.096 12.5 2.0 0.26 11.2 0.4 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5572) Arf PF00025.21 KKK42740.1 - 0.014 14.8 0.0 0.034 13.6 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Folliculin PF11704.8 KKK42741.1 - 0.0073 16.2 0.1 0.011 15.6 0.1 1.4 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport TrmB PF01978.19 KKK42742.1 - 0.023 14.6 0.2 0.03 14.2 0.2 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SelB-wing_2 PF09106.11 KKK42742.1 - 0.088 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor SelB, winged helix FeoC PF09012.10 KKK42742.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 FeoC like transcriptional regulator Terminase_6C PF17289.2 KKK42743.1 - 0.012 15.7 0.3 0.029 14.5 0.3 1.6 1 0 0 1 1 1 0 Terminase RNaseH-like domain DUF4041 PF13250.6 KKK42743.1 - 0.44 10.5 6.1 3.7 7.5 1.5 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4041) Response_reg PF00072.24 KKK42744.1 - 1.2e-15 57.6 0.0 1.3e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Alpha_adaptinC2 PF02883.20 KKK42747.1 - 0.00062 20.1 0.1 0.0019 18.5 0.1 1.8 1 1 0 1 1 1 1 Adaptin C-terminal domain DUF2808 PF10989.8 KKK42747.1 - 0.0021 18.0 0.1 0.0036 17.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) Prok-JAB PF14464.6 KKK42749.1 - 2.4e-09 37.0 0.0 2.9e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 KKK42749.1 - 0.00084 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Proteasome PF00227.26 KKK42750.1 - 5.4e-41 140.2 0.1 6.4e-41 139.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit SQHop_cyclase_N PF13249.6 KKK42751.1 - 0.03 13.4 0.5 0.22 10.6 0.1 2.4 2 1 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Ribosomal_S8e PF01201.22 KKK42752.1 - 9.9e-28 97.0 2.5 1.6e-27 96.3 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e HypA PF01155.19 KKK42753.1 - 2.2e-28 98.5 0.4 2.5e-28 98.4 0.4 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 KKK42753.1 - 0.048 13.6 0.9 0.12 12.4 0.9 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-DNL PF05180.12 KKK42753.1 - 0.061 13.3 2.2 0.063 13.2 1.1 1.6 2 0 0 2 2 2 0 DNL zinc finger tRNA-synt_1f PF01921.18 KKK42753.1 - 0.15 10.9 0.0 0.16 10.9 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) Elf1 PF05129.13 KKK42753.1 - 0.38 10.8 3.3 5 7.2 0.2 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like SRP19 PF01922.17 KKK42754.1 - 4.9e-20 72.3 0.2 6.2e-20 72.0 0.2 1.1 1 0 0 1 1 1 1 SRP19 protein AMP-binding PF00501.28 KKK42755.1 - 1.5e-05 23.8 0.0 1.6e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Fer4_7 PF12838.7 KKK42759.1 - 1.6e-08 35.0 0.7 1.3e-06 28.9 0.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK42759.1 - 1.1e-07 31.4 6.0 8.1e-06 25.4 3.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK42759.1 - 4.8e-07 30.6 1.2 2.9e-05 24.9 0.5 2.0 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK42759.1 - 5.7e-06 26.4 2.0 7.7e-06 26.0 2.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK42759.1 - 1.1e-05 25.3 6.6 8.4e-05 22.5 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KKK42759.1 - 1.2e-05 25.3 11.9 0.00055 20.0 1.1 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK42759.1 - 0.00023 21.2 2.0 0.00028 20.9 2.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK42759.1 - 0.0004 20.9 1.6 0.00043 20.8 0.7 1.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK42759.1 - 0.00075 19.9 0.3 0.0012 19.2 0.3 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK42759.1 - 0.00085 19.3 2.3 0.00085 19.3 2.3 1.8 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 KKK42759.1 - 0.0045 17.4 0.8 0.0045 17.4 0.8 1.8 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_22 PF17179.4 KKK42759.1 - 0.013 16.3 0.4 0.017 15.9 0.4 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK42759.1 - 0.045 14.7 8.3 0.18 12.8 5.4 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK42759.1 - 0.12 12.9 4.6 3.4 8.3 3.6 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KKK42759.1 - 0.16 12.7 4.6 0.78 10.5 2.7 2.3 2 1 0 2 2 2 0 4Fe-4S single cluster domain SNAP PF14938.6 KKK42761.1 - 0.0013 18.2 0.9 0.0038 16.7 0.8 1.6 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KKK42761.1 - 0.024 14.7 0.5 8.4 6.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK42761.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M24 PF00557.24 KKK42762.1 - 4.7e-39 134.2 0.0 6.5e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KKK42762.1 - 4.9e-05 24.0 0.0 0.0001 22.9 0.0 1.6 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF4866 PF16160.5 KKK42762.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) BtrH_N PF14399.6 KKK42762.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Glycos_trans_3N PF02885.17 KKK42763.1 - 5.3e-12 45.4 0.0 9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PEPcase_2 PF14010.6 KKK42767.1 - 2.2e-140 468.4 0.0 2.5e-140 468.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase GTP_EFTU_D2 PF03144.25 KKK42768.1 - 5.2e-09 36.4 0.2 1.4e-08 35.0 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KKK42768.1 - 0.00056 19.7 0.6 0.0013 18.6 0.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Aconitase PF00330.20 KKK42769.1 - 5e-173 576.3 0.0 6.4e-173 576.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK42769.1 - 1.6e-40 138.4 0.0 3.3e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Citrate_synt PF00285.21 KKK42770.1 - 2.4e-115 385.5 0.0 2.9e-115 385.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Macro_2 PF14519.6 KKK42770.1 - 0.015 14.6 0.1 5 6.4 0.0 2.3 2 0 0 2 2 2 0 Macro-like domain AhpC-TSA PF00578.21 KKK42773.1 - 4.5e-09 36.3 0.1 5.2e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK42773.1 - 2.2e-07 30.7 0.0 2.7e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 KKK42773.1 - 0.071 12.6 0.0 0.074 12.6 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) APH PF01636.23 KKK42774.1 - 3e-09 37.2 0.0 4.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KKK42774.1 - 0.0016 18.0 0.8 0.0034 17.0 0.8 1.5 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KKK42774.1 - 0.0022 17.6 6.5 0.013 15.1 4.8 2.5 1 1 1 2 2 2 1 Choline/ethanolamine kinase Kinase-PolyVal PF18762.1 KKK42774.1 - 0.12 12.3 6.1 13 5.7 4.8 2.8 2 1 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF2207 PF09972.9 KKK42775.1 - 1 8.1 7.7 0.88 8.3 7.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TPR_12 PF13424.6 KKK42776.1 - 3.5e-14 52.8 4.8 1.9e-09 37.7 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK42776.1 - 5.2e-12 45.0 4.5 1.5e-05 24.6 0.1 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK42776.1 - 3.6e-10 39.8 1.9 1.1e-06 28.2 0.0 3.1 3 0 0 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 KKK42776.1 - 1e-08 34.6 7.9 0.00025 20.9 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK42776.1 - 8.2e-07 28.8 10.3 4.6e-06 26.4 0.1 5.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KKK42776.1 - 3.8e-06 26.6 3.5 0.00013 21.8 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK42776.1 - 7.5e-06 25.6 0.1 0.00079 19.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK42776.1 - 1.4e-05 24.7 3.6 0.00051 19.7 0.1 4.2 5 0 0 5 5 5 1 TPR repeat TPR_14 PF13428.6 KKK42776.1 - 0.016 16.0 1.4 3.7 8.6 0.0 4.3 5 1 1 6 6 4 0 Tetratricopeptide repeat DUF2861 PF11060.8 KKK42776.1 - 0.025 14.2 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) SNAP PF14938.6 KKK42776.1 - 0.048 13.1 0.1 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 KKK42776.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.7 3 1 1 4 4 4 0 26S proteasome subunit RPN7 SRP_TPR_like PF17004.5 KKK42776.1 - 3.2 7.8 6.5 4.3 7.4 0.0 3.9 5 0 0 5 5 5 0 Putative TPR-like repeat FMN_dh PF01070.18 KKK42777.1 - 7.2e-56 189.7 0.5 8.2e-56 189.5 0.5 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK42777.1 - 4.8e-09 35.8 0.8 8.5e-09 35.0 0.6 1.5 1 1 1 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KKK42777.1 - 3e-07 30.0 1.2 0.00014 21.2 0.1 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase IMPDH PF00478.25 KKK42777.1 - 5.2e-07 29.0 5.3 4.7e-06 25.8 2.8 2.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KKK42777.1 - 6e-07 29.0 2.3 0.0028 17.0 0.2 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KKK42777.1 - 5.2e-06 26.1 0.7 0.00017 21.1 0.1 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 KKK42777.1 - 7.6e-06 25.5 0.5 9.1e-06 25.3 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase NanE PF04131.14 KKK42777.1 - 1.9e-05 23.9 0.5 0.15 11.2 0.1 2.2 1 1 1 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 KKK42777.1 - 0.00044 19.5 0.1 0.028 13.6 0.0 2.0 1 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.12 KKK42777.1 - 0.0011 18.4 0.6 0.7 9.3 0.1 2.3 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 KKK42777.1 - 0.0086 15.2 0.7 0.052 12.6 0.6 1.9 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) Ribul_P_3_epim PF00834.19 KKK42777.1 - 0.09 12.1 1.5 0.82 9.0 0.2 2.6 2 1 1 3 3 3 0 Ribulose-phosphate 3 epimerase family PcrB PF01884.17 KKK42777.1 - 0.17 11.4 2.3 1.4 8.3 0.4 2.1 1 1 1 2 2 2 0 PcrB family HATPase_c PF02518.26 KKK42779.1 - 1.1e-16 61.3 0.2 1.8e-16 60.6 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK42779.1 - 2.1e-05 24.5 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain SepF PF04472.12 KKK42780.1 - 5.2e-08 33.0 0.0 6.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Cell division protein SepF Nitroreductase PF00881.24 KKK42781.1 - 1.2e-23 84.1 0.0 2.9e-14 53.5 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 KKK42781.1 - 1.4e-10 41.2 0.2 0.041 13.4 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase Nitroreductase PF00881.24 KKK42782.1 - 6e-26 91.5 0.1 1.8e-13 50.9 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 KKK42782.1 - 3.2e-07 30.2 0.1 0.00014 21.5 0.0 2.4 2 1 0 2 2 2 2 Putative TM nitroreductase Spt46 PF17734.1 KKK42782.1 - 0.087 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 MFS_1 PF07690.16 KKK42783.1 - 3e-30 105.4 39.7 6.1e-27 94.5 30.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK42783.1 - 0.016 13.8 30.3 0.15 10.5 5.8 3.3 1 1 2 3 3 3 0 MFS/sugar transport protein PGG PF13962.6 KKK42783.1 - 4.2 7.2 16.2 2 8.3 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function PAP2 PF01569.21 KKK42784.1 - 1.4e-18 67.0 3.8 1.4e-18 67.0 3.8 1.9 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKK42784.1 - 5.6e-12 45.7 4.1 9.6e-12 45.0 4.1 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KKK42784.1 - 0.001 19.5 7.7 0.001 19.5 7.7 2.4 2 1 0 2 2 2 1 PAP2 superfamily C-terminal Prominin PF05478.11 KKK42784.1 - 0.069 11.1 1.8 0.12 10.3 1.8 1.3 1 0 0 1 1 1 0 Prominin DUF2628 PF10947.8 KKK42784.1 - 1.4 9.3 14.7 0.46 10.9 8.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) 2TM PF13239.6 KKK42785.1 - 2.1e-15 56.8 18.0 3.2e-09 37.0 1.0 2.2 2 0 0 2 2 2 2 2TM domain DUF2244 PF10003.9 KKK42785.1 - 0.0072 16.0 12.9 0.61 9.8 0.2 2.1 2 0 0 2 2 2 2 Integral membrane protein (DUF2244) DUF1418 PF07214.12 KKK42785.1 - 0.22 11.4 4.6 0.053 13.4 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) TRAP-gamma PF07074.12 KKK42785.1 - 1.6 8.2 12.5 0.048 13.2 2.7 2.2 2 1 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3918 PF13056.6 KKK42785.1 - 2.6 7.7 5.5 4.5 7.0 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) PadR PF03551.14 KKK42786.1 - 6e-18 64.6 0.0 1.2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family RTP PF02334.16 KKK42786.1 - 0.00021 21.9 0.7 0.00061 20.4 0.2 2.0 1 1 1 2 2 2 1 Replication terminator protein zinc_ribbon_15 PF17032.5 KKK42786.1 - 0.0012 19.5 0.4 0.0019 18.9 0.4 1.4 1 0 0 1 1 1 1 zinc-ribbon family HxlR PF01638.17 KKK42786.1 - 0.0021 17.9 0.1 0.0051 16.6 0.0 1.7 2 0 0 2 2 2 1 HxlR-like helix-turn-helix zf-ribbon_3 PF13248.6 KKK42786.1 - 0.0034 16.7 1.6 0.0057 16.0 1.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK42786.1 - 0.018 14.8 2.6 0.036 13.8 2.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain HTH_34 PF13601.6 KKK42786.1 - 0.024 14.8 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.22 KKK42786.1 - 0.039 13.9 0.0 0.28 11.1 0.0 2.2 1 1 0 1 1 1 0 MarR family DZR PF12773.7 KKK42786.1 - 0.05 13.6 0.2 0.076 13.0 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon COG2 PF06148.11 KKK42786.1 - 0.056 13.5 0.1 0.1 12.7 0.0 1.5 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TrmB PF01978.19 KKK42786.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HypA PF01155.19 KKK42786.1 - 0.065 13.3 1.1 0.3 11.1 1.6 1.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 KKK42786.1 - 0.12 12.0 1.4 3.3 7.5 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_7 PF02591.15 KKK42786.1 - 0.29 11.3 1.4 2 8.7 0.1 2.4 2 0 0 2 2 2 0 C4-type zinc ribbon domain Rubredoxin_2 PF18073.1 KKK42786.1 - 1.8 8.3 4.6 6.6 6.5 4.7 1.8 1 1 0 1 1 1 0 Rubredoxin metal binding domain ESCRT-II PF05871.12 KKK42787.1 - 0.033 14.4 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 ESCRT-II complex subunit KASH_CCD PF14662.6 KKK42790.1 - 0.0014 18.5 48.7 0.0057 16.5 14.7 3.3 2 1 1 3 3 3 2 Coiled-coil region of CCDC155 or KASH DUF1825 PF08855.10 KKK42790.1 - 0.0016 18.3 0.6 0.0016 18.3 0.6 4.1 1 1 1 4 4 4 2 Domain of unknown function (DUF1825) Sec34 PF04136.15 KKK42790.1 - 0.0037 17.2 2.7 0.0037 17.2 2.7 3.5 2 1 1 3 3 3 1 Sec34-like family DUF4472 PF14739.6 KKK42790.1 - 0.0044 17.7 10.0 0.0044 17.7 10.0 4.2 1 1 3 4 4 4 1 Domain of unknown function (DUF4472) HOOK PF05622.12 KKK42790.1 - 0.007 14.6 40.5 0.0081 14.4 40.5 1.0 1 0 0 1 1 1 1 HOOK protein Spc7 PF08317.11 KKK42790.1 - 0.013 14.4 48.2 0.76 8.6 14.3 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4715 PF15835.5 KKK42790.1 - 0.053 13.6 12.8 0.34 11.0 0.3 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4715) RUN PF02759.19 KKK42790.1 - 2 8.4 11.5 3.5 7.6 0.1 2.8 2 1 0 2 2 2 0 RUN domain DUF1515 PF07439.11 KKK42790.1 - 5.2 7.1 18.0 4.4 7.4 5.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1515) TPR_MLP1_2 PF07926.12 KKK42790.1 - 6 6.9 44.5 5.3 7.1 2.9 4.7 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KKK42790.1 - 8.1 6.6 39.2 4.3 7.5 17.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DNA_binding_1 PF01035.20 KKK42791.1 - 2.5e-20 72.4 0.0 3.3e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain CwfJ_C_2 PF04676.14 KKK42791.1 - 0.058 14.3 0.0 0.087 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 Aminotran_1_2 PF00155.21 KKK42792.1 - 2.8e-63 214.3 0.0 3.2e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK42792.1 - 0.028 13.4 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KKK42792.1 - 0.04 12.4 0.0 0.065 11.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN5_C PF18098.1 KKK42792.1 - 0.13 12.4 0.6 0.37 10.9 0.2 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain Aminotran_MocR PF12897.7 KKK42792.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.4 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase EamA PF00892.20 KKK42794.1 - 1.4e-25 90.1 39.6 8e-15 55.2 17.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 KKK42794.1 - 0.0032 16.6 8.8 0.039 13.0 0.8 2.6 1 1 0 2 2 2 2 Magnesium transporter NIPA DMT_6 PF04342.12 KKK42794.1 - 0.22 11.8 11.8 0.32 11.2 0.4 3.1 3 1 0 3 3 3 0 Putative member of DMT superfamily (DUF486) Halogen_Hydrol PF10112.9 KKK42794.1 - 1.7 8.6 0.0 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Proteasome PF00227.26 KKK42795.1 - 5.7e-47 159.7 0.3 6.5e-47 159.5 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit ThuA PF06283.11 KKK42796.1 - 0.00049 20.4 0.0 0.00086 19.6 0.0 1.3 1 1 0 1 1 1 1 Trehalose utilisation GATase1_like PF07090.11 KKK42796.1 - 0.02 14.3 0.0 0.056 12.9 0.0 1.8 1 1 0 1 1 1 0 Putative glutamine amidotransferase ABC_transp_aux PF09822.9 KKK42796.1 - 0.022 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Radical_SAM PF04055.21 KKK42797.1 - 1.4e-08 35.3 1.6 1.8e-08 34.9 0.0 2.0 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK42797.1 - 6.9e-06 26.4 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK42797.1 - 2.1e-05 24.6 0.4 8e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain HHH_5 PF14520.6 KKK42798.1 - 5.1e-09 36.6 3.2 5.1e-09 36.6 3.2 2.7 2 1 0 2 2 1 1 Helix-hairpin-helix domain FKBP26_C PF18046.1 KKK42798.1 - 1.5e-08 34.6 4.5 1.5e-08 34.6 4.5 2.0 2 0 0 2 2 2 1 FKBP26_C-terminal HHH PF00633.23 KKK42798.1 - 2.4e-06 27.1 0.4 8.1e-05 22.3 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif FKBP_C PF00254.28 KKK42798.1 - 2.7e-06 27.6 0.8 9.8e-06 25.8 0.7 2.1 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HHH_2 PF12826.7 KKK42798.1 - 0.00067 19.7 0.2 0.0023 18.0 0.1 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 KKK42798.1 - 0.00067 19.4 0.2 0.0032 17.2 0.2 2.2 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_Rpb2_6 PF00562.28 KKK42798.1 - 0.0013 17.9 5.8 0.0024 17.0 5.8 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 IMS_HHH PF11798.8 KKK42798.1 - 0.019 15.3 1.0 7.5 7.1 0.0 3.3 3 0 0 3 3 3 0 IMS family HHH motif DUF4332 PF14229.6 KKK42798.1 - 0.037 14.3 0.1 0.18 12.0 0.0 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4332) HHH_8 PF14716.6 KKK42798.1 - 0.045 14.1 0.2 0.045 14.1 0.2 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain Ribosomal_S13 PF00416.22 KKK42798.1 - 0.049 14.0 5.3 0.16 12.4 1.7 2.8 2 1 1 3 3 3 0 Ribosomal protein S13/S18 HHH_3 PF12836.7 KKK42798.1 - 0.079 13.2 1.3 0.24 11.7 0.1 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 KKK42798.1 - 0.085 13.5 6.9 0.15 12.7 4.6 2.6 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Myotoxins PF00819.17 KKK42798.1 - 0.18 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Myotoxin, crotamine HAD_2 PF13419.6 KKK42799.1 - 3.7e-13 49.9 0.4 3.7e-13 49.9 0.4 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK42799.1 - 1.4e-09 38.6 0.0 9.4e-09 35.9 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase OmpH PF03938.14 KKK42799.1 - 0.032 14.6 15.5 0.074 13.4 15.5 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KKK42799.1 - 4.9 6.4 6.4 6.9 5.9 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-grasp_3 PF02655.14 KKK42800.1 - 2.8e-05 24.2 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KKK42800.1 - 0.0004 20.0 0.2 0.0044 16.6 0.0 2.4 2 1 1 3 3 3 1 ATP-grasp domain DNA_gyraseA_C PF03989.13 KKK42800.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller ATP-grasp PF02222.22 KKK42800.1 - 0.027 14.0 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 KKK42801.1 - 0.0055 16.3 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKK42801.1 - 0.0058 16.2 0.1 0.017 14.6 0.0 1.8 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus Ins134_P3_kin PF05770.11 KKK42802.1 - 3.2e-08 33.3 2.6 2.2e-06 27.3 0.3 2.3 1 1 1 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain RimK PF08443.11 KKK42802.1 - 0.00086 18.9 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain PBP_like PF12727.7 KKK42802.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain DUF3801 PF12687.7 KKK42802.1 - 0.3 11.1 1.1 0.41 10.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Inos-1-P_synth PF01658.17 KKK42803.1 - 2.9e-19 69.3 0.0 5.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 KKK42803.1 - 6e-06 25.9 0.0 6.9e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase DUF1611_N PF17396.2 KKK42803.1 - 0.0079 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1611_N) Rossmann-like domain Ins134_P3_kin PF05770.11 KKK42804.1 - 9.7e-09 35.0 2.3 7.2e-07 28.9 0.4 2.5 2 1 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain BacA PF02673.18 KKK42805.1 - 1.4e-46 159.3 18.0 1.6e-46 159.1 18.0 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA LMWPc PF01451.21 KKK42806.1 - 2.6e-19 70.0 0.0 3.3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PTS_IIB PF02302.17 KKK42806.1 - 0.00029 21.5 0.3 0.22 12.3 0.0 2.2 1 1 1 2 2 2 2 PTS system, Lactose/Cellobiose specific IIB subunit DUF2170 PF09938.9 KKK42806.1 - 0.046 13.4 0.1 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) Isochorismatase PF00857.20 KKK42807.1 - 3.7e-27 95.6 0.0 4.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF998 PF06197.13 KKK42808.1 - 4e-07 29.8 7.3 4.9e-07 29.5 7.3 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF998 PF06197.13 KKK42809.1 - 7.5e-10 38.7 12.5 1.1e-09 38.2 12.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Cas1_AcylT PF07779.12 KKK42809.1 - 0.0046 15.9 9.6 0.0051 15.8 9.6 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Elf4 PF07011.11 KKK42810.1 - 0.015 15.2 0.3 3.7 7.5 0.0 2.1 1 1 1 2 2 2 0 Early Flowering 4 domain CpXC PF14353.6 KKK42811.1 - 0.021 14.8 0.2 0.043 13.8 0.2 1.5 1 1 0 1 1 1 0 CpXC protein CheW PF01584.19 KKK42813.1 - 3.9e-26 91.3 0.6 6e-26 90.7 0.6 1.3 1 1 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 KKK42814.1 - 8e-29 100.1 1.4 9.4e-29 99.8 1.4 1.1 1 0 0 1 1 1 1 Response regulator receiver domain P2 PF07194.11 KKK42815.1 - 1.3e-16 60.4 1.0 1.3e-16 60.4 1.0 4.2 4 0 0 4 4 4 2 P2 response regulator binding domain HATPase_c PF02518.26 KKK42815.1 - 3.9e-14 53.1 1.5 9.3e-14 51.9 0.2 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CheW PF01584.19 KKK42815.1 - 4.9e-12 45.7 0.4 1.8e-11 43.8 0.1 2.1 2 0 0 2 2 2 1 CheW-like domain Hpt PF01627.23 KKK42815.1 - 7.7e-11 42.1 0.0 2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Hpt domain H-kinase_dim PF02895.14 KKK42815.1 - 3.2e-05 24.2 0.6 0.00014 22.1 0.6 2.1 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c_2 PF13581.6 KKK42815.1 - 0.028 14.4 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain 7TMR-HDED PF07697.11 KKK42815.1 - 0.17 12.0 7.2 2.5 8.2 7.2 2.7 1 1 0 1 1 1 0 7TM-HD extracellular Op_neuropeptide PF08035.11 KKK42815.1 - 0.66 9.9 2.4 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Opioids neuropeptide DUF11 PF01345.18 KKK42816.1 - 0.0011 19.2 0.0 0.011 16.0 0.0 2.6 3 1 0 3 3 3 1 Domain of unknown function DUF11 Alpha_adaptinC2 PF02883.20 KKK42816.1 - 0.078 13.3 0.2 13 6.2 0.0 3.3 3 0 0 3 3 3 0 Adaptin C-terminal domain CheC PF04509.12 KKK42818.1 - 1.4e-36 124.1 4.1 5.7e-11 42.1 0.1 5.0 5 0 0 5 5 5 4 CheC-like family CheW PF01584.19 KKK42818.1 - 3.7e-17 62.3 1.7 7.6e-17 61.2 1.7 1.5 1 0 0 1 1 1 1 CheW-like domain CheX PF13690.6 KKK42818.1 - 1.4e-08 34.7 3.9 0.031 14.4 0.0 4.0 4 0 0 4 4 4 3 Chemotaxis phosphatase CheX Gelsolin PF00626.22 KKK42819.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Gelsolin repeat CheR PF01739.18 KKK42820.1 - 4.7e-45 153.5 0.0 4.7e-45 153.5 0.0 1.5 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.6 KKK42820.1 - 6.3e-05 22.8 0.1 0.00067 19.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK42820.1 - 0.00065 20.4 0.0 0.0054 17.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK42820.1 - 0.0016 19.1 0.0 0.0033 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK42820.1 - 0.0018 18.1 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KKK42820.1 - 0.003 17.2 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 KKK42820.1 - 0.0053 17.5 0.0 0.03 15.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KKK42820.1 - 0.046 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MPM1 PF17234.2 KKK42820.1 - 0.12 12.6 3.7 0.25 11.6 3.7 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Methyltransf_24 PF13578.6 KKK42820.1 - 0.24 12.4 0.0 0.44 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheB_methylest PF01339.17 KKK42821.1 - 4.9e-56 189.1 0.0 7e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.24 KKK42821.1 - 4.9e-22 78.2 0.4 1.5e-21 76.7 0.4 1.8 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 KKK42821.1 - 0.029 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain CheD PF03975.13 KKK42822.1 - 1.6e-23 82.9 0.0 2.1e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction CheC PF04509.12 KKK42823.1 - 2.5e-18 65.7 0.5 4.8e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 CheC-like family CheX PF13690.6 KKK42823.1 - 0.0026 17.9 0.1 3.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Chemotaxis phosphatase CheX MOZART2 PF12926.7 KKK42823.1 - 0.11 12.2 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Ras PF00071.22 KKK42824.1 - 1e-36 126.0 0.0 1.6e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42824.1 - 1.5e-22 80.1 0.2 2.8e-22 79.2 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42824.1 - 5e-14 52.1 0.0 9e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK42824.1 - 5.2e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK42824.1 - 1.3e-05 25.2 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KKK42824.1 - 3e-05 23.7 0.0 0.00071 19.2 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Robl_LC7 PF03259.17 KKK42824.1 - 0.0006 19.5 0.0 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 Roadblock/LC7 domain FeoB_N PF02421.18 KKK42824.1 - 0.00085 18.9 0.0 0.017 14.7 0.0 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 KKK42824.1 - 0.0011 18.8 0.7 0.085 12.6 0.0 2.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KKK42824.1 - 0.0013 18.1 0.4 0.0042 16.5 0.1 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region LPD18 PF18832.1 KKK42824.1 - 0.035 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 RNase_Zc3h12a PF11977.8 KKK42825.1 - 0.022 14.6 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain RHH_3 PF12651.7 KKK42826.1 - 0.09 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribbon-helix-helix domain Na_Ca_ex PF01699.24 KKK42827.1 - 2.8e-12 46.9 8.8 3.1e-12 46.7 8.8 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein BET PF17035.5 KKK42831.1 - 0.024 14.8 1.7 0.047 13.9 1.5 1.6 1 1 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation nsp8 PF08717.10 KKK42831.1 - 0.078 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 nsp8 replicase DUF5131 PF07505.11 KKK42833.1 - 4.7e-07 29.5 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF5131) MethyltransfD12 PF02086.15 KKK42834.1 - 9.9e-07 28.7 9.8 3.4e-05 23.6 3.3 2.3 2 0 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase zinc_ribbon_2 PF13240.6 KKK42838.1 - 0.0095 15.6 12.9 0.1 12.4 4.4 2.8 3 0 0 3 3 3 2 zinc-ribbon domain zf-RING_4 PF14570.6 KKK42838.1 - 0.013 15.2 10.5 0.068 13.0 1.1 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KKK42838.1 - 0.042 13.9 11.0 0.16 12.0 11.0 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 KKK42838.1 - 0.2 11.5 11.8 0.39 10.6 11.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KKK42838.1 - 0.34 11.2 13.3 3.1 8.1 13.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 KKK42838.1 - 0.38 11.0 10.3 1.8 8.9 10.4 2.0 1 1 0 1 1 1 0 TFIIH C1-like domain zinc_ribbon_10 PF10058.9 KKK42838.1 - 0.98 9.2 9.8 1.3 8.8 9.0 1.7 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ribbon_3 PF13248.6 KKK42838.1 - 4.8 6.7 11.6 0.8 9.2 0.5 2.5 2 1 1 3 3 3 0 zinc-ribbon domain DDDD PF10161.9 KKK42839.1 - 0.22 11.3 0.7 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Radical_SAM PF04055.21 KKK42840.1 - 1.3e-18 68.0 1.1 1.3e-17 64.7 0.0 2.5 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK42840.1 - 2e-07 31.3 1.4 7.9e-07 29.4 0.0 2.4 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK42840.1 - 0.00092 19.3 0.0 0.00092 19.3 0.0 2.7 3 0 0 3 3 3 1 4Fe-4S single cluster domain LRR_8 PF13855.6 KKK42841.1 - 2.6e-12 46.3 17.1 1.6e-09 37.4 7.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KKK42841.1 - 2.7e-10 40.3 14.2 7.3e-05 23.1 1.2 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KKK42841.1 - 0.00074 19.1 1.0 0.00082 18.9 1.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KKK42841.1 - 0.0023 18.2 13.8 1.3 9.8 1.1 4.3 3 1 1 4 4 4 2 Leucine Rich Repeat DUF2322 PF10084.9 KKK42841.1 - 0.079 13.0 0.1 0.57 10.3 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) CSTF_C PF14304.6 KKK42841.1 - 0.12 12.0 0.4 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal RsmF_methylt_CI PF17126.5 KKK42841.1 - 0.12 12.4 0.0 21 5.2 0.0 2.5 2 1 1 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 KKK42841.1 - 3.7 7.9 15.6 0.93 9.7 1.2 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Abhydrolase_1 PF00561.20 KKK42842.1 - 3.2e-20 72.8 0.0 1.8e-14 54.0 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK42842.1 - 2.5e-15 57.7 0.0 3e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK42842.1 - 1.5e-10 40.7 0.0 4.6e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KKK42842.1 - 1.5e-05 25.3 0.0 6.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.14 KKK42842.1 - 0.00027 19.8 0.0 0.04 12.6 0.0 2.1 2 0 0 2 2 2 2 Ndr family Peptidase_S15 PF02129.18 KKK42842.1 - 0.0045 16.6 0.0 0.045 13.3 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KKK42842.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Palm_thioest PF02089.15 KKK42842.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 KKK42842.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 KKK42843.1 - 4.3e-47 160.1 0.1 5.3e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK42843.1 - 1.6e-39 135.9 0.0 1.9e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK42843.1 - 6.3e-07 29.5 0.2 1.2e-06 28.6 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK42843.1 - 0.0014 18.2 0.1 0.003 17.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KKK42843.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.26 KKK42843.1 - 0.0077 16.2 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KKK42843.1 - 0.058 13.6 0.2 0.096 12.9 0.1 1.4 1 1 0 1 1 1 0 TrkA-N domain FtsK_SpoIIIE PF01580.18 KKK42843.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family tRNA-synt_1e PF01406.19 KKK42844.1 - 5e-101 338.0 2.7 7.6e-101 337.4 2.7 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 KKK42844.1 - 1.2e-17 64.1 2.9 2.3e-17 63.2 1.7 2.1 2 0 0 2 2 2 1 DALR domain tRNA-synt_1g PF09334.11 KKK42844.1 - 2.8e-11 42.8 0.2 3.3e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKK42844.1 - 1.8e-07 29.8 0.0 2.2e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 KKK42844.1 - 0.0033 16.4 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) Ras PF00071.22 KKK42845.1 - 4.5e-50 169.4 0.1 5.1e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42845.1 - 1.3e-29 102.8 0.0 1.9e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42845.1 - 1.9e-16 60.0 0.0 2.4e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK42845.1 - 1.2e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK42845.1 - 2.6e-06 26.9 0.1 3.1e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KKK42845.1 - 0.00013 21.5 0.0 0.021 14.3 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KKK42845.1 - 0.00028 20.9 0.0 0.041 13.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KKK42845.1 - 0.0069 15.8 0.0 0.0097 15.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 KKK42845.1 - 0.0076 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 KKK42845.1 - 0.016 15.6 0.0 0.022 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KKK42845.1 - 0.026 14.3 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KKK42845.1 - 0.075 12.8 0.0 5.1 6.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF296 PF03479.15 KKK42846.1 - 8.8e-24 84.0 0.1 1e-23 83.8 0.1 1.0 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Ras PF00071.22 KKK42847.1 - 1.8e-46 157.7 0.0 2.1e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42847.1 - 1.6e-27 96.1 0.0 2.2e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42847.1 - 1.4e-12 47.4 0.1 1.6e-12 47.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK42847.1 - 1.8e-07 31.2 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK42847.1 - 0.0002 20.9 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KKK42847.1 - 0.011 15.1 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KKK42847.1 - 0.027 14.8 0.0 0.054 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 KKK42847.1 - 0.035 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 KKK42847.1 - 0.048 13.1 0.0 0.052 13.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 KKK42849.1 - 3.9e-50 169.6 0.2 4.5e-50 169.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42849.1 - 9.8e-31 106.5 0.1 1.3e-30 106.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42849.1 - 1.3e-14 54.1 0.1 1.5e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42849.1 - 4.3e-07 29.5 0.3 4.8e-07 29.4 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK42849.1 - 2.7e-05 24.2 0.0 4.7e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KKK42849.1 - 0.00079 18.8 0.1 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 KKK42849.1 - 0.0027 17.5 0.1 0.27 11.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KKK42849.1 - 0.011 16.2 0.2 0.016 15.8 0.2 1.2 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KKK42849.1 - 0.012 14.8 0.8 0.086 12.0 0.8 2.0 1 1 0 1 1 1 0 G-protein alpha subunit DUSP PF06337.12 KKK42849.1 - 0.014 16.0 0.0 0.022 15.4 0.0 1.4 1 0 0 1 1 1 0 DUSP domain AAA_16 PF13191.6 KKK42849.1 - 0.046 14.1 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.18 KKK42849.1 - 0.062 12.8 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 KKK42849.1 - 0.066 12.7 0.0 0.093 12.2 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KKK42849.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DLIC PF05783.11 KKK42849.1 - 0.085 11.7 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 KKK42849.1 - 0.09 12.7 0.0 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KKK42849.1 - 0.11 12.2 0.2 0.57 9.9 0.2 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Aminotran_1_2 PF00155.21 KKK42850.1 - 1.7e-55 188.7 0.0 2e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK42850.1 - 1.8e-09 37.1 0.0 3.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KKK42850.1 - 1.4e-06 27.1 0.0 2.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KKK42850.1 - 3.9e-06 26.4 0.0 6.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 KKK42850.1 - 8.2e-06 24.9 0.3 5.7e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Allinase Met_gamma_lyase PF06838.11 KKK42850.1 - 0.05 12.1 0.1 0.14 10.6 0.0 1.6 2 0 0 2 2 2 0 Methionine gamma-lyase AAA PF00004.29 KKK42851.1 - 7.6e-90 298.2 0.2 2.8e-45 154.0 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK42851.1 - 1.8e-28 98.0 0.1 5.7e-16 58.1 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KKK42851.1 - 3.8e-19 68.6 0.1 2.7e-18 65.9 0.1 2.5 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 KKK42851.1 - 8.6e-15 55.3 0.0 6.4e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK42851.1 - 4.6e-13 49.2 0.0 5.8e-05 22.9 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KKK42851.1 - 7.2e-11 41.9 0.1 0.00022 20.6 0.0 2.9 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_16 PF13191.6 KKK42851.1 - 8.7e-11 42.5 0.0 0.00017 22.0 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 KKK42851.1 - 5.7e-10 39.3 0.0 0.0011 18.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KKK42851.1 - 3.7e-09 36.7 0.5 0.018 15.0 0.0 4.6 4 2 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KKK42851.1 - 4.2e-09 36.8 0.2 0.037 14.3 0.0 4.4 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.22 KKK42851.1 - 1.7e-08 34.8 0.0 0.0011 19.4 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.6 KKK42851.1 - 1.8e-08 34.7 0.0 0.0087 16.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 KKK42851.1 - 3.8e-08 33.0 0.7 5.6e-07 29.2 0.3 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 KKK42851.1 - 1.1e-07 31.8 0.0 0.0048 16.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 KKK42851.1 - 1.1e-07 31.7 0.0 0.0012 18.6 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KKK42851.1 - 1.3e-06 28.9 0.1 0.078 13.5 0.0 3.4 3 0 0 3 3 3 2 ABC transporter AAA_18 PF13238.6 KKK42851.1 - 2.2e-06 28.3 0.0 0.034 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KKK42851.1 - 6.4e-06 25.7 0.4 0.026 13.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KKK42851.1 - 1.3e-05 24.8 0.0 0.02 14.4 0.0 2.5 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 KKK42851.1 - 3.3e-05 24.2 0.0 0.069 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KKK42851.1 - 4.9e-05 23.0 0.1 1.9 8.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain Bac_DnaA PF00308.18 KKK42851.1 - 7.2e-05 22.7 0.0 0.099 12.5 0.0 2.9 2 1 0 2 2 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 KKK42851.1 - 0.00016 20.9 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KKK42851.1 - 0.00017 21.4 0.0 0.42 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KKK42851.1 - 0.00021 21.3 0.9 0.23 11.3 0.0 3.5 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea PhoH PF02562.16 KKK42851.1 - 0.00022 20.7 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein ATPase PF06745.13 KKK42851.1 - 0.0005 19.5 4.0 0.13 11.6 0.0 3.7 3 1 0 4 4 4 1 KaiC TsaE PF02367.17 KKK42851.1 - 0.00053 20.0 0.0 0.9 9.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KKK42851.1 - 0.00063 19.1 0.0 0.44 9.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.9 KKK42851.1 - 0.00072 19.3 0.0 0.32 10.7 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 KKK42851.1 - 0.00085 19.3 0.0 0.56 10.1 0.0 3.1 2 1 1 3 3 3 1 Rad17 P-loop domain DUF815 PF05673.13 KKK42851.1 - 0.00087 18.5 0.0 0.69 9.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 KKK42851.1 - 0.0012 18.9 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 KKK42851.1 - 0.0015 17.8 0.0 0.44 9.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.6 KKK42851.1 - 0.0043 17.6 1.4 11 6.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KKK42851.1 - 0.005 16.8 0.1 0.64 9.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 KKK42851.1 - 0.0059 16.4 0.0 0.022 14.5 0.0 2.0 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.25 KKK42851.1 - 0.0089 15.7 0.0 0.34 10.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 KKK42851.1 - 0.02 15.3 0.0 4.7 7.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 KKK42851.1 - 0.021 14.6 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IPT PF01745.16 KKK42851.1 - 0.039 13.4 0.1 1.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Isopentenyl transferase DUF2075 PF09848.9 KKK42851.1 - 0.071 12.3 0.0 6.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KKK42851.1 - 0.083 12.7 0.0 6.8 6.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KKK42851.1 - 0.13 12.0 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KKK42851.1 - 0.17 11.3 1.2 16 4.9 0.0 3.1 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit Vps4_C PF09336.10 KKK42851.1 - 0.22 11.5 1.5 25 5.0 0.0 3.0 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 KKK42851.1 - 0.34 11.2 1.1 13 6.1 0.1 3.0 2 2 0 2 2 2 0 AAA domain KTI12 PF08433.10 KKK42852.1 - 1.5e-31 109.8 1.1 2.4e-30 105.9 0.2 1.9 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KKK42852.1 - 1.1e-10 41.9 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KKK42852.1 - 3.2e-10 40.1 0.0 5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KKK42852.1 - 0.00012 22.6 1.2 0.00043 20.8 0.1 2.3 2 2 0 2 2 2 1 AAA domain 6PF2K PF01591.18 KKK42852.1 - 0.00057 19.2 0.1 0.0024 17.2 0.1 2.0 1 1 0 1 1 1 1 6-phosphofructo-2-kinase DrrA_P4M PF14860.6 KKK42852.1 - 0.076 12.9 1.8 0.3 10.9 1.8 2.1 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Zeta_toxin PF06414.12 KKK42852.1 - 0.1 11.9 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ploopntkinase3 PF18751.1 KKK42852.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 GIY-YIG PF01541.24 KKK42853.1 - 2.1e-12 47.2 4.6 2.5e-12 46.9 4.6 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 KKK42853.1 - 0.016 15.8 0.5 0.017 15.6 0.5 1.1 1 0 0 1 1 1 0 T5orf172 domain TFIIE_alpha PF02002.17 KKK42854.1 - 0.004 17.0 2.8 0.0099 15.7 0.0 2.4 2 1 0 2 2 2 1 TFIIE alpha subunit HTH_34 PF13601.6 KKK42854.1 - 0.006 16.7 0.2 0.02 15.1 0.1 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.22 KKK42854.1 - 0.031 14.2 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 MarR family XendoU PF09412.10 KKK42855.1 - 0.022 14.0 1.5 0.023 13.9 1.5 1.1 1 0 0 1 1 1 0 Endoribonuclease XendoU TBP PF00352.21 KKK42856.1 - 9.2e-55 182.6 2.2 1.1e-26 92.5 0.3 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KKK42856.1 - 0.00017 21.6 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Ras PF00071.22 KKK42857.1 - 5.5e-48 162.6 0.0 6.2e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42857.1 - 1.4e-31 109.1 0.0 3.5e-31 107.9 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42857.1 - 2.2e-17 63.0 0.2 2.8e-17 62.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KKK42857.1 - 4.7e-06 26.6 0.1 0.092 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KKK42857.1 - 0.00039 19.9 0.1 0.00056 19.3 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK42857.1 - 0.00071 19.6 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK42857.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KKK42857.1 - 0.03 14.7 0.1 0.06 13.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KKK42857.1 - 0.033 14.0 0.1 5.3 6.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KKK42857.1 - 0.036 14.0 0.0 0.086 12.8 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 KKK42857.1 - 0.044 13.8 0.3 0.12 12.4 0.3 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KKK42857.1 - 0.091 12.2 0.2 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 KKK42857.1 - 0.096 12.2 0.2 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KKK42857.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2507 PF10702.9 KKK42858.1 - 4.3e-07 29.9 0.0 7.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2507) V4R PF02830.18 KKK42858.1 - 2.3e-06 27.5 1.9 3.6e-06 26.9 1.3 1.6 2 0 0 2 2 2 1 V4R domain Thioredoxin PF00085.20 KKK42859.1 - 1.3e-07 31.5 0.0 1.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKK42859.1 - 1.9e-07 31.5 0.1 1.2e-06 29.0 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KKK42859.1 - 3.7e-05 23.7 0.0 5.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_8 PF13905.6 KKK42859.1 - 9.6e-05 22.6 0.2 0.004 17.5 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_4 PF13462.6 KKK42859.1 - 0.00099 19.3 1.0 0.0023 18.1 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin Glutaredoxin PF00462.24 KKK42859.1 - 0.0015 18.7 0.1 0.0029 17.8 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 KKK42859.1 - 0.002 18.5 0.1 0.0024 18.3 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) OST3_OST6 PF04756.13 KKK42859.1 - 0.0085 15.5 0.0 0.0091 15.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 KKK42859.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Ras PF00071.22 KKK42860.1 - 2.7e-32 111.6 0.0 3e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK42860.1 - 1.7e-15 57.3 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK42860.1 - 1.2e-06 28.1 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK42860.1 - 0.0012 18.3 0.1 0.0018 17.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK42860.1 - 0.034 14.0 0.0 0.046 13.6 0.0 1.3 1 1 0 1 1 1 0 RsgA GTPase ATP_bind_1 PF03029.17 KKK42860.1 - 0.038 13.8 0.0 0.056 13.2 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Ribosomal_S8 PF00410.19 KKK42865.1 - 1.1e-23 83.5 0.1 1.9e-23 82.8 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L6 PF00347.23 KKK42866.1 - 4.3e-20 72.2 4.5 5.9e-11 42.9 4.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF2196 PF09962.9 KKK42866.1 - 0.075 13.0 2.1 10 6.2 0.2 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2196) Ribosomal_L32e PF01655.18 KKK42867.1 - 2.8e-27 95.2 1.0 3.8e-27 94.8 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 Hexapep PF00132.24 KKK42869.1 - 5.8e-10 38.5 7.0 1.2e-07 31.1 0.7 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK42869.1 - 2.3e-07 30.5 5.2 2.6e-06 27.1 0.2 2.6 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF86 PF01934.17 KKK42870.1 - 2.5e-28 98.3 3.6 3.2e-28 98.0 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 NTase_sub_bind PF08780.11 KKK42870.1 - 0.03 14.3 0.4 0.044 13.8 0.4 1.4 1 1 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like zf-C2H2_9 PF16293.5 KKK42870.1 - 0.044 13.6 2.3 0.13 12.2 0.1 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) 5_3_exonuc PF01367.20 KKK42870.1 - 0.078 13.6 0.8 0.2 12.3 0.2 1.9 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF2018 PF09442.10 KKK42870.1 - 0.34 11.9 4.3 0.5 11.4 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Polbeta PF18765.1 KKK42871.1 - 2e-21 75.8 0.7 3.2e-21 75.2 0.7 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK42871.1 - 4.3e-06 26.9 0.3 9.6e-06 25.8 0.3 1.8 1 1 0 1 1 1 1 Nucleotidyltransferase domain DUF3870 PF12986.7 KKK42871.1 - 0.056 13.7 0.2 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) DUF3645 PF12359.8 KKK42871.1 - 0.18 11.2 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) CN_hydrolase PF00795.22 KKK42872.1 - 1.5e-41 142.5 0.0 1.7e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ADH_N PF08240.12 KKK42873.1 - 9.9e-24 83.3 0.0 2.4e-23 82.1 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK42873.1 - 1.8e-19 70.0 0.0 3.9e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KKK42873.1 - 0.0011 19.4 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 KKK42873.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK42873.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-C2HE PF16278.5 KKK42873.1 - 0.041 14.3 0.0 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Gp_dh_N PF00044.24 KKK42873.1 - 0.057 13.8 0.7 10 6.5 0.1 3.0 2 1 1 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK42873.1 - 0.077 13.1 0.1 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KKK42873.1 - 0.097 12.9 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 KKK42873.1 - 0.11 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Hexapep PF00132.24 KKK42874.1 - 1.5e-05 24.5 6.4 0.0084 15.8 0.2 4.7 5 1 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK42874.1 - 0.00083 19.1 7.4 0.2 11.4 0.4 3.6 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF2695 PF10905.8 KKK42875.1 - 0.00012 22.2 0.4 0.00073 19.7 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2695) PI3Ka PF00613.20 KKK42875.1 - 0.0076 15.7 0.7 3 7.2 0.0 2.9 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RecR PF02132.15 KKK42876.1 - 0.012 15.1 1.2 0.024 14.2 1.2 1.6 1 1 0 1 1 1 0 RecR protein zf-RanBP PF00641.18 KKK42876.1 - 0.034 13.4 1.4 0.96 8.8 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF3271 PF11675.8 KKK42876.1 - 0.11 11.8 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Acetyltransf_1 PF00583.25 KKK42882.1 - 2.2e-08 34.3 0.1 2.5e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK42882.1 - 2e-05 24.5 0.1 2.4e-05 24.3 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK42882.1 - 3e-05 24.1 0.1 8.8e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK42882.1 - 0.00029 21.2 0.0 0.00036 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 KKK42882.1 - 0.0011 18.8 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 KKK42882.1 - 0.0022 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 KKK42882.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Polbeta PF18765.1 KKK42883.1 - 4.9e-17 61.8 1.9 5.5e-17 61.6 1.9 1.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK42883.1 - 4.1e-12 46.2 0.6 4.6e-12 46.1 0.6 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain MdcG PF10620.9 KKK42883.1 - 0.21 11.4 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Ribosomal_L12_N PF16320.5 KKK42883.1 - 0.44 10.3 2.6 0.36 10.6 1.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain zinc_ribbon_6 PF14599.6 KKK42887.1 - 0.0075 16.3 4.0 0.12 12.4 0.4 2.1 1 1 1 2 2 2 2 Zinc-ribbon TPR_12 PF13424.6 KKK42888.1 - 1.2e-17 63.9 0.2 5.4e-11 42.6 0.1 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK42888.1 - 9.2e-13 47.3 1.5 0.0072 16.4 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KKK42888.1 - 4.5e-10 39.1 0.2 0.01 15.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK42888.1 - 1.6e-09 37.2 6.2 0.022 14.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK42888.1 - 5.5e-07 29.2 6.9 0.014 15.0 0.6 3.4 3 0 0 3 3 3 3 TPR repeat TPR_8 PF13181.6 KKK42888.1 - 1e-06 28.5 6.5 0.0058 16.8 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 KKK42888.1 - 2.6e-05 24.2 1.5 0.11 12.5 0.1 3.2 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 KKK42888.1 - 0.00012 21.6 0.1 0.00055 19.4 0.0 1.8 1 1 1 2 2 2 1 MalT-like TPR region Methyltransf_23 PF13489.6 KKK42888.1 - 0.00013 21.9 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPR_7 PF13176.6 KKK42888.1 - 0.002 18.0 0.5 3.3 7.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 KKK42888.1 - 0.0029 17.1 0.3 0.0076 15.7 0.3 1.5 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP Methyltransf_25 PF13649.6 KKK42888.1 - 0.0068 17.1 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ComR_TPR PF18710.1 KKK42888.1 - 0.031 13.8 0.3 0.075 12.6 0.1 1.7 2 0 0 2 2 2 0 ComR tetratricopeptide TPR_19 PF14559.6 KKK42888.1 - 0.062 13.8 0.1 12 6.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 KKK42888.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPR_16 PF13432.6 KKK42888.1 - 0.095 13.4 0.0 37 5.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK42888.1 - 0.1 12.8 1.8 18 5.6 0.2 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KKK42888.1 - 0.13 13.2 0.0 17 6.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 KKK42888.1 - 0.16 12.0 9.2 0.35 10.9 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 KKK42888.1 - 0.18 12.5 0.0 0.38 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SRP_TPR_like PF17004.5 KKK42888.1 - 0.2 11.7 2.8 12 5.9 0.0 2.5 2 1 0 2 2 2 0 Putative TPR-like repeat HATPase_c PF02518.26 KKK42889.1 - 1.6e-20 73.7 0.7 4.3e-20 72.3 0.7 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK42889.1 - 3.2e-10 39.9 0.0 1.3e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KKK42889.1 - 2.8e-08 34.0 0.1 1.1e-07 32.1 0.1 2.0 1 1 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 KKK42889.1 - 0.0028 17.6 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS PF00989.25 KKK42889.1 - 0.06 13.3 0.0 0.53 10.3 0.0 2.2 1 1 0 1 1 1 0 PAS fold PAS_4 PF08448.10 KKK42889.1 - 0.089 13.1 0.0 0.45 10.8 0.0 2.0 1 1 0 1 1 1 0 PAS fold SirA PF10747.9 KKK42889.1 - 0.13 12.6 0.8 0.63 10.4 0.1 2.4 3 0 0 3 3 3 0 Sporulation inhibitor of replication protein SirA Sulfatase PF00884.23 KKK42890.1 - 3e-59 200.9 0.0 3.8e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK42890.1 - 5.8e-15 55.7 0.0 1.4e-14 54.5 0.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KKK42890.1 - 1e-07 32.2 0.0 2.6e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KKK42890.1 - 0.027 13.1 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF5538 PF17692.1 KKK42890.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5538) Acetyltransf_1 PF00583.25 KKK42891.1 - 0.025 14.8 0.1 0.065 13.5 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK42891.1 - 0.051 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SQHop_cyclase_C PF13243.6 KKK42892.1 - 0.0016 17.6 0.2 1.2 8.1 0.0 2.4 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain PPO1_KFDV PF12143.8 KKK42893.1 - 0.019 15.0 0.3 0.023 14.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) Glyco_trans_A_1 PF09318.10 KKK42893.1 - 0.032 13.9 0.1 0.033 13.9 0.1 1.1 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A HTH_12 PF08461.10 KKK42897.1 - 0.045 13.7 0.1 0.062 13.3 0.1 1.3 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain SBDS_C PF09377.10 KKK42897.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain Yip1 PF04893.17 KKK42898.1 - 3.8e-06 26.7 19.9 5.2e-06 26.3 19.9 1.2 1 0 0 1 1 1 1 Yip1 domain DUF2154 PF09922.9 KKK42899.1 - 0.011 15.6 4.3 0.21 11.5 0.2 3.5 4 1 0 4 4 4 0 Cell wall-active antibiotics response 4TMS YvqF Cadherin-like PF12733.7 KKK42899.1 - 0.59 10.7 7.2 5.2 7.7 0.6 3.7 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain TatD_DNase PF01026.21 KKK42900.1 - 6.7e-40 137.1 0.0 7.9e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Phage_Mu_Gam PF07352.12 KKK42901.1 - 0.014 15.4 4.4 0.02 14.8 4.1 1.6 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF3086 PF11285.8 KKK42901.1 - 0.014 14.5 1.6 0.02 14.0 1.6 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) Baculo_PEP_C PF04513.12 KKK42901.1 - 0.021 14.9 0.1 0.21 11.6 0.2 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 KKK42901.1 - 0.055 13.5 2.6 0.54 10.3 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KKK42901.1 - 0.11 11.9 6.5 0.14 11.6 6.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Helo_like_N PF17111.5 KKK42901.1 - 0.31 10.4 4.5 1.2 8.4 3.3 2.0 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF1053 PF06327.14 KKK42901.1 - 0.52 10.9 5.0 5.6 7.6 2.8 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) Ax_dynein_light PF10211.9 KKK42901.1 - 1.2 9.1 9.1 0.66 9.9 5.9 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain DUF5082 PF16888.5 KKK42901.1 - 2.7 8.3 10.1 39 4.6 8.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TcpS PF17456.2 KKK42901.1 - 4 7.5 11.1 17 5.4 7.9 2.4 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S DUF4200 PF13863.6 KKK42903.1 - 0.01 16.2 25.7 0.016 15.6 11.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF1192 PF06698.11 KKK42903.1 - 0.019 15.0 4.0 0.019 15.0 4.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Fib_alpha PF08702.10 KKK42903.1 - 4.6 7.4 10.2 2.3 8.4 6.7 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 KKK42903.1 - 7.7 5.8 23.8 11 5.3 23.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NosD PF05048.13 KKK42904.1 - 5.2e-65 219.1 137.7 1.3e-28 100.0 42.7 3.3 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK42904.1 - 9.9e-53 178.2 135.2 1.6e-22 80.1 41.0 5.4 1 1 4 5 5 5 4 Right handed beta helix region Big_7 PF17957.1 KKK42904.1 - 2.2 9.1 15.7 0.42 11.4 3.4 4.4 3 1 1 4 4 4 0 Bacterial Ig domain Aconitase PF00330.20 KKK42905.1 - 1.1e-104 351.0 1.9 9.7e-103 344.6 1.9 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK42905.1 - 1.5e-21 77.1 0.2 3.3e-21 76.0 0.2 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Peptidase_A4 PF01828.17 KKK42905.1 - 0.0067 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase A4 family DUF521 PF04412.13 KKK42905.1 - 0.0071 15.1 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Alkyl_sulf_dimr PF14863.6 KKK42906.1 - 0.0089 16.5 5.2 0.83 10.1 1.0 2.4 2 0 0 2 2 2 2 Alkyl sulfatase dimerisation TPR_2 PF07719.17 KKK42906.1 - 0.013 15.6 1.2 14 6.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1826 PF08856.11 KKK42906.1 - 1.4 8.8 4.0 3.3 7.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1826) DUF5603 PF18231.1 KKK42907.1 - 0.033 14.5 0.3 0.036 14.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5603) NMO PF03060.15 KKK42910.1 - 8.8e-25 87.8 0.0 9.8e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KKK42910.1 - 0.00032 19.8 0.1 0.0005 19.2 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK42910.1 - 0.045 12.7 0.2 0.067 12.2 0.2 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KKK42910.1 - 0.07 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Fer4_7 PF12838.7 KKK42911.1 - 0.0006 20.3 0.0 0.016 15.8 0.0 2.5 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK42911.1 - 0.02 15.0 2.2 0.02 15.0 2.2 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Radical_SAM_N PF08497.10 KKK42911.1 - 0.18 11.0 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Radical SAM N-terminal Fer4_16 PF13484.6 KKK42911.1 - 0.51 11.3 7.4 28 5.8 0.0 2.9 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK42911.1 - 1.8 8.8 10.8 2.4 8.4 4.3 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK42911.1 - 8 6.7 10.8 46 4.2 6.7 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain UPF0182 PF03699.13 KKK42912.1 - 4.4e-13 48.3 9.5 4.4e-13 48.3 9.5 3.2 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0182) Phage_holin_3_6 PF07332.11 KKK42912.1 - 0.0056 16.7 3.0 0.0056 16.7 3.0 2.2 2 1 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III zf-B_box PF00643.24 KKK42912.1 - 0.64 10.2 3.6 1.1 9.5 3.6 1.2 1 0 0 1 1 1 0 B-box zinc finger NMO PF03060.15 KKK42913.1 - 2.5e-37 129.0 0.6 5.9e-37 127.8 0.4 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 KKK42913.1 - 2.3e-11 43.3 1.7 1.1e-08 34.5 1.7 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KKK42913.1 - 4.8e-05 22.8 2.0 8.7e-05 21.9 2.0 1.5 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KKK42913.1 - 0.0001 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 KKK42913.1 - 0.00034 19.8 0.2 0.019 14.1 0.1 2.2 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 KKK42913.1 - 0.001 18.4 0.4 0.0052 16.1 0.4 2.1 3 0 0 3 3 3 1 Thiamine monophosphate synthase NanE PF04131.14 KKK42913.1 - 0.0013 17.9 0.1 0.0022 17.2 0.1 1.3 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 KKK42913.1 - 0.0061 15.6 1.0 0.0097 15.0 1.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Trp_syntA PF00290.20 KKK42913.1 - 0.0063 15.4 0.1 1.2 7.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan synthase alpha chain Glu_synthase PF01645.17 KKK42913.1 - 0.016 14.4 3.8 0.067 12.3 3.8 2.0 1 1 0 1 1 1 0 Conserved region in glutamate synthase Radical_SAM PF04055.21 KKK42913.1 - 0.048 14.0 0.0 0.089 13.2 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily DUF1729 PF08354.10 KKK42913.1 - 0.053 12.4 0.1 0.11 11.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) DUF561 PF04481.12 KKK42913.1 - 0.16 11.1 0.0 0.7 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF561) PFL-like PF02901.15 KKK42915.1 - 7.6e-57 193.4 0.2 2.5e-55 188.4 0.2 2.0 1 1 0 1 1 1 1 Pyruvate formate lyase-like CBFD_NFYB_HMF PF00808.23 KKK42915.1 - 1.4 9.3 4.5 2.9 8.2 0.4 2.3 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PIN PF01850.21 KKK42916.1 - 8.5e-14 52.1 0.1 1e-13 51.9 0.1 1.0 1 0 0 1 1 1 1 PIN domain Helicase_C_2 PF13307.6 KKK42916.1 - 0.037 14.2 0.1 0.044 13.9 0.1 1.1 1 0 0 1 1 1 0 Helicase C-terminal domain PCP_red PF08369.10 KKK42916.1 - 0.042 14.1 0.1 0.093 13.0 0.1 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit VAPB_antitox PF02697.14 KKK42917.1 - 0.047 14.5 6.3 0.26 12.1 6.3 1.9 1 1 0 1 1 1 0 Putative antitoxin DUF3385 PF11865.8 KKK42918.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) NUDIX PF00293.28 KKK42919.1 - 6.7e-18 65.0 0.1 8.5e-18 64.7 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Acyl_transf_3 PF01757.22 KKK42920.1 - 1.1e-13 51.0 35.7 1.3e-13 50.7 35.7 1.0 1 0 0 1 1 1 1 Acyltransferase family Acyl_transf_3 PF01757.22 KKK42921.1 - 0.025 13.7 5.5 0.035 13.2 5.5 1.2 1 0 0 1 1 1 0 Acyltransferase family DUF2214 PF09980.9 KKK42921.1 - 0.074 12.9 0.3 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2214) AAA_lid_3 PF17862.1 KKK42924.1 - 1.5e-15 56.7 0.0 2.1e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 AAA+ lid domain Insulin_TMD PF17870.1 KKK42925.1 - 2.1 8.5 6.3 0.52 10.4 1.8 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF5099 PF17025.5 KKK42926.1 - 0.19 12.2 1.8 16 6.0 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5099) MFS_2 PF13347.6 KKK42927.1 - 5.4e-29 101.0 26.3 5.4e-29 101.0 26.3 1.4 1 1 1 2 2 2 2 MFS/sugar transport protein Peptidase_M42 PF05343.14 KKK42928.1 - 1.5e-88 296.6 0.0 1.7e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 KKK42928.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KKK42928.1 - 0.0048 16.6 0.0 0.6 9.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 DUF313 PF03754.13 KKK42928.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF313) Fer4 PF00037.27 KKK42932.1 - 3.6e-11 42.4 15.0 6.6e-08 32.0 3.6 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK42932.1 - 3.8e-09 36.5 10.7 3.8e-09 36.5 10.7 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK42932.1 - 5.7e-08 33.2 23.5 9.8e-06 26.1 13.5 2.7 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK42932.1 - 5.8e-08 32.7 21.5 8.6e-06 25.8 12.4 3.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK42932.1 - 6.1e-08 32.4 10.4 1.5e-05 24.8 3.1 3.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK42932.1 - 1.4e-07 31.6 11.2 1.4e-07 31.6 11.2 2.9 1 1 2 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK42932.1 - 1.7e-07 30.9 11.0 8.9e-05 22.4 2.1 3.6 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK42932.1 - 1.3e-06 29.2 16.3 0.0018 19.2 1.2 3.5 2 1 1 3 3 3 3 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK42932.1 - 0.00026 21.2 2.2 0.00026 21.2 2.2 3.8 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_22 PF17179.4 KKK42932.1 - 0.002 18.9 7.4 0.024 15.5 1.5 3.6 2 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK42932.1 - 0.0039 17.7 26.1 0.035 14.7 1.6 3.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK42932.1 - 0.0041 17.8 2.5 0.0041 17.8 2.5 3.1 2 1 1 3 3 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.6 KKK42932.1 - 0.015 15.8 2.0 0.015 15.8 2.0 3.5 3 1 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 KKK42932.1 - 2.6 8.5 31.4 0.86 10.1 2.3 3.5 1 1 3 4 4 4 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK42933.1 - 1.9e-15 55.9 14.4 3.6e-08 32.9 4.8 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK42933.1 - 1.3e-12 47.2 13.9 9.9e-08 31.7 1.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK42933.1 - 3.1e-11 43.2 20.4 1.6e-08 34.5 11.7 2.9 2 1 3 5 5 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK42933.1 - 1.4e-08 34.7 20.9 1.6e-06 28.1 12.4 3.0 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK42933.1 - 3.7e-07 30.6 10.7 3.7e-07 30.6 10.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain TrmB PF01978.19 KKK42933.1 - 4.4e-07 29.7 0.0 9.8e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fer4_9 PF13187.6 KKK42933.1 - 4.6e-06 26.7 20.9 9.2e-06 25.7 11.5 2.6 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK42933.1 - 8e-05 22.5 13.0 0.00049 20.0 1.8 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK42933.1 - 0.00011 23.0 9.8 0.001 19.9 2.8 3.3 3 1 1 4 4 2 2 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 KKK42933.1 - 0.00018 22.0 12.5 0.1 13.1 1.0 2.9 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 KKK42933.1 - 0.00089 19.6 1.1 0.00089 19.6 1.1 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain MarR_2 PF12802.7 KKK42933.1 - 0.0014 18.4 0.2 0.0067 16.3 0.1 1.9 2 0 0 2 2 2 1 MarR family Penicillinase_R PF03965.16 KKK42933.1 - 0.0033 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 Penicillinase repressor Fer4_15 PF13459.6 KKK42933.1 - 0.0043 17.7 16.2 0.52 11.1 2.9 3.4 2 2 0 2 2 2 2 4Fe-4S single cluster domain HTH_36 PF13730.6 KKK42933.1 - 0.013 15.5 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 KKK42933.1 - 0.018 15.4 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.6 KKK42933.1 - 0.03 14.8 0.2 0.29 11.7 0.1 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_29 PF13551.6 KKK42933.1 - 0.031 14.3 0.0 0.24 11.4 0.0 2.3 1 1 1 2 2 2 0 Winged helix-turn helix Fer4_17 PF13534.6 KKK42933.1 - 0.033 14.7 0.6 0.033 14.7 0.6 3.3 2 1 1 3 3 2 0 4Fe-4S dicluster domain AbiEi_4 PF13338.6 KKK42933.1 - 0.037 14.2 0.1 0.085 13.0 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Fer4_8 PF13183.6 KKK42933.1 - 0.058 13.9 0.5 0.058 13.9 0.5 3.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain HTH_3 PF01381.22 KKK42933.1 - 0.17 12.0 0.5 30 4.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix Fer4_18 PF13746.6 KKK42933.1 - 6.2 7.1 16.7 0.4 10.9 10.0 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain zf-ribbon_3 PF13248.6 KKK42934.1 - 0.0025 17.2 2.4 0.0051 16.2 2.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK42934.1 - 0.0032 17.1 2.5 0.0058 16.3 2.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK42934.1 - 0.011 15.7 0.5 0.023 14.7 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon BSD PF03909.17 KKK42934.1 - 0.054 13.5 0.4 0.21 11.6 0.1 2.3 3 0 0 3 3 3 0 BSD domain PyrI_C PF02748.15 KKK42934.1 - 0.45 10.5 3.1 0.41 10.6 0.3 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FGase PF05013.12 KKK42935.1 - 1.4e-49 169.2 0.0 1.6e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase RNA_POL_M_15KD PF02150.16 KKK42936.1 - 0.0095 15.8 2.5 0.0095 15.8 2.5 3.9 4 1 0 4 4 4 2 RNA polymerases M/15 Kd subunit YqgF PF14639.6 KKK42936.1 - 0.045 13.5 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 PIN_12 PF16289.5 KKK42937.1 - 0.014 15.9 4.1 0.018 15.5 4.0 1.3 1 1 0 1 1 1 0 PIN domain MazE_antitoxin PF04014.18 KKK42938.1 - 2.1e-07 30.7 0.0 3.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin Thump_like PF18096.1 KKK42938.1 - 0.0036 17.2 0.1 0.0066 16.4 0.1 1.4 1 0 0 1 1 1 1 THUMP domain-like PrlF_antitoxin PF15937.5 KKK42938.1 - 0.0078 16.6 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 prlF antitoxin for toxin YhaV_toxin eIF-1a PF01176.19 KKK42938.1 - 0.056 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Colicin_immun PF09204.10 KKK42940.1 - 0.014 15.9 0.4 0.072 13.6 0.4 2.3 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity ANAPC3 PF12895.7 KKK42940.1 - 0.15 12.3 0.9 19 5.5 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Cut8 PF08559.10 KKK42940.1 - 0.49 10.0 4.4 0.22 11.1 0.5 2.4 3 0 0 3 3 3 0 Cut8, nuclear proteasome tether protein DUF4795 PF16043.5 KKK42940.1 - 6.6 6.3 9.1 0.9 9.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) SWIM PF04434.17 KKK42942.1 - 0.00028 20.5 1.8 0.00051 19.6 1.8 1.5 1 0 0 1 1 1 1 SWIM zinc finger Tax PF02959.16 KKK42943.1 - 0.039 13.4 0.0 0.045 13.2 0.0 1.1 1 0 0 1 1 1 0 HTLV Tax CorA PF01544.18 KKK42943.1 - 0.062 12.6 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cupin_2 PF07883.11 KKK42944.1 - 8.2e-11 41.5 0.0 1.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KKK42944.1 - 5.8e-05 23.0 0.0 7.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 KKK42944.1 - 0.00016 21.3 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KKK42944.1 - 0.00024 21.0 0.0 0.0003 20.7 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase EutQ PF06249.12 KKK42944.1 - 0.00067 19.4 0.0 0.00077 19.3 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ CENP-C_C PF11699.8 KKK42944.1 - 0.0017 18.5 0.0 0.0034 17.6 0.0 1.6 1 1 1 2 2 2 1 Mif2/CENP-C like Cupin_1 PF00190.22 KKK42944.1 - 0.065 12.8 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF2129 PF09902.9 KKK42944.1 - 0.13 12.3 1.2 3.6 7.7 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) NiFeSe_Hases PF00374.19 KKK42945.1 - 1.3e-15 57.4 0.0 7.1e-15 54.9 0.0 1.9 1 1 0 1 1 1 1 Nickel-dependent hydrogenase UPF0122 PF04297.14 KKK42948.1 - 0.014 15.6 0.4 0.018 15.3 0.4 1.1 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like TPR_1 PF00515.28 KKK42949.1 - 3.3e-43 143.8 27.2 6e-09 35.3 0.0 7.4 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 KKK42949.1 - 2.7e-40 133.2 19.4 2e-08 33.7 0.0 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 KKK42949.1 - 2e-35 118.0 26.7 8.7e-09 34.9 0.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.6 KKK42949.1 - 1.8e-32 110.7 19.4 3.4e-09 36.2 1.1 7.4 3 1 4 7 7 7 7 TPR repeat TPR_12 PF13424.6 KKK42949.1 - 1.4e-22 79.8 9.3 1.4e-07 31.7 0.2 6.3 3 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KKK42949.1 - 1.8e-19 68.6 11.1 3e-07 30.4 0.8 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KKK42949.1 - 3.9e-18 65.8 0.0 7.2e-09 36.2 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK42949.1 - 6.6e-18 63.3 5.2 0.0002 21.2 0.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK42949.1 - 1.3e-15 56.7 0.0 0.00049 20.7 0.0 6.8 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 KKK42949.1 - 9.5e-14 50.8 10.0 0.045 13.6 0.2 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KKK42949.1 - 2.1e-12 47.4 7.6 8.4e-07 29.4 0.3 5.3 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 KKK42949.1 - 2.9e-10 40.1 7.1 0.13 13.0 0.0 6.3 7 0 0 7 7 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK42949.1 - 1e-07 32.1 12.2 0.022 15.0 0.1 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KKK42949.1 - 1.9e-07 31.1 0.0 0.015 15.4 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.12 KKK42949.1 - 0.00011 22.8 2.6 0.39 11.5 0.0 4.2 3 1 0 3 3 3 1 Sel1 repeat TPR_MalT PF17874.1 KKK42949.1 - 0.0011 18.4 0.2 0.62 9.4 0.0 3.1 3 1 0 4 4 4 1 MalT-like TPR region TPR_3 PF07720.12 KKK42949.1 - 0.0015 18.5 16.6 0.13 12.3 1.1 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KKK42949.1 - 0.0018 17.5 3.6 0.018 14.3 2.7 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Vta1_C PF18097.1 KKK42949.1 - 0.0029 17.3 0.2 1.1 9.1 0.1 3.4 3 0 0 3 3 3 1 Vta1 C-terminal domain Sedlin_N PF04628.13 KKK42949.1 - 0.019 15.1 4.7 0.1 12.7 3.9 2.4 1 1 1 2 2 2 0 Sedlin, N-terminal conserved region DUF627 PF04781.12 KKK42949.1 - 0.047 13.7 6.8 22 5.1 0.1 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF627) Rapsyn_N PF10579.9 KKK42949.1 - 0.087 12.9 1.9 2.3 8.4 0.1 3.4 3 1 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPPII_N PF12583.8 KKK42949.1 - 0.12 13.0 1.7 0.34 11.5 1.7 1.8 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal FBA PF04300.13 KKK42949.1 - 0.49 10.1 4.3 3.3 7.4 0.2 2.3 2 0 0 2 2 2 0 F-box associated region TPR_20 PF14561.6 KKK42949.1 - 0.6 10.5 8.5 2.9 8.3 0.1 4.9 4 2 1 6 6 5 0 Tetratricopeptide repeat Mistic PF11458.8 KKK42949.1 - 0.86 9.6 17.1 0.14 12.2 1.7 4.2 4 0 0 4 4 4 0 Membrane-integrating protein Mistic Peptidase_C10 PF01640.17 KKK42949.1 - 8 6.7 6.8 1.2 9.4 2.1 2.1 2 1 0 2 2 2 0 Peptidase C10 family Myco_arth_vir_N PF09610.10 KKK42953.1 - 0.44 10.7 3.1 0.84 9.8 3.1 1.4 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) LRR_8 PF13855.6 KKK42954.1 - 7.6e-27 92.9 36.5 8.3e-09 35.1 7.5 4.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KKK42954.1 - 2.3e-17 62.8 52.4 9.2e-05 22.7 8.0 6.6 4 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KKK42954.1 - 1.9e-07 30.8 14.7 0.00012 21.7 2.7 2.7 2 1 1 3 3 3 2 Leucine-rich repeat DZR PF12773.7 KKK42954.1 - 0.00013 22.0 1.0 0.00025 21.0 1.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK42954.1 - 0.00018 20.8 3.1 0.00036 19.8 3.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain LRR_1 PF00560.33 KKK42954.1 - 0.0019 18.5 37.4 1.6 9.6 1.2 9.5 8 2 0 8 8 8 1 Leucine Rich Repeat zinc_ribbon_2 PF13240.6 KKK42954.1 - 0.0045 16.6 8.4 0.012 15.3 8.4 1.8 1 0 0 1 1 1 1 zinc-ribbon domain LRR_5 PF13306.6 KKK42954.1 - 0.014 15.4 6.6 0.36 10.8 0.8 3.5 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 KKK42954.1 - 0.035 14.1 0.2 19 5.4 0.0 4.3 2 2 2 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain DUF2322 PF10084.9 KKK42954.1 - 0.039 14.0 0.4 21 5.3 0.0 3.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) Nudix_N_2 PF14803.6 KKK42954.1 - 0.26 11.3 5.8 2 8.4 0.2 2.5 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_15 PF17032.5 KKK42954.1 - 3.4 8.5 8.1 1.9 9.3 5.7 1.9 2 0 0 2 2 2 0 zinc-ribbon family PfkB PF00294.24 KKK42955.1 - 1.9e-63 214.6 0.0 2.4e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Glyco_hydro_3_C PF01915.22 KKK42956.1 - 7e-54 182.9 0.0 1.2e-53 182.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK42956.1 - 5.1e-48 164.1 0.0 9e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK42956.1 - 3.2e-22 78.4 0.0 6.9e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PHP PF02811.19 KKK42957.1 - 1.9e-09 38.1 0.6 3.6e-09 37.1 0.6 1.7 1 1 0 1 1 1 1 PHP domain SCP2 PF02036.17 KKK42958.1 - 6.6e-10 39.4 0.0 9.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Sgf11 PF08209.11 KKK42958.1 - 0.16 11.5 0.2 0.16 11.5 0.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.6 KKK42958.1 - 1.4 8.7 7.2 0.23 11.3 1.8 2.3 2 0 0 2 2 2 0 zinc-ribbon domain GDPD PF03009.17 KKK42959.1 - 8.1e-16 58.5 0.0 2.8e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3169 PF11368.8 KKK42960.1 - 0.023 14.2 0.3 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) MCPsignal PF00015.21 KKK42961.1 - 5.3e-31 107.7 26.8 1.3e-29 103.2 12.4 3.3 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 7TM_GPCR_Srh PF10318.9 KKK42961.1 - 0.033 13.2 1.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh Prefoldin_2 PF01920.20 KKK42961.1 - 1.1 9.3 7.8 0.23 11.4 3.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4064 PF13273.6 KKK42961.1 - 2.1 8.7 8.0 1.1 9.5 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF148 PF02520.17 KKK42961.1 - 2.2 8.5 10.3 0.93 9.6 1.3 3.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 AFOR_N PF02730.15 KKK42965.1 - 1.7e-52 178.2 0.7 2.4e-52 177.7 0.7 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain AFOR_C PF01314.18 KKK42965.1 - 1.1e-11 44.4 0.0 2.3e-11 43.3 0.0 1.6 2 0 0 2 2 2 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 sCache_3_3 PF17202.4 KKK42965.1 - 0.029 14.8 0.1 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 Single cache domain 3 YHS PF04945.13 KKK42965.1 - 0.12 12.5 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 YHS domain Ub-Mut7C PF14451.6 KKK42966.1 - 0.00018 21.3 0.0 0.00026 20.7 0.0 1.3 1 1 0 1 1 1 1 Mut7-C ubiquitin ThiS PF02597.20 KKK42966.1 - 0.00077 20.0 0.0 0.00095 19.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family S4 PF01479.25 KKK42966.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 S4 domain Peptidase_S24 PF00717.23 KKK42967.1 - 0.0013 18.7 1.0 0.0028 17.6 0.3 1.8 1 1 0 1 1 1 1 Peptidase S24-like DUF1287 PF06940.11 KKK42967.1 - 0.0042 16.7 0.1 0.0079 15.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1287) DUF1939 PF09154.10 KKK42967.1 - 0.08 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) DUF1040 PF06288.13 KKK42968.1 - 0.0038 17.6 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1040) XRN_N PF03159.18 KKK42969.1 - 0.068 12.6 1.0 0.069 12.6 1.0 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Fer4 PF00037.27 KKK42970.1 - 0.00017 21.3 6.2 0.00025 20.7 6.2 1.3 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_7 PF12838.7 KKK42970.1 - 0.0027 18.3 0.2 0.004 17.7 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain ApoA-II PF04711.13 KKK42970.1 - 0.016 15.4 2.2 0.86 9.8 0.2 2.3 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) Fer4_21 PF14697.6 KKK42970.1 - 0.068 13.3 3.6 0.11 12.6 3.6 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain TraB PF01963.17 KKK42970.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 TraB family MCR_D PF02505.14 KKK42970.1 - 0.19 11.5 1.6 0.34 10.8 0.2 1.8 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D Fer4_3 PF12798.7 KKK42970.1 - 2.5 9.2 9.1 3.8 8.7 9.1 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain DUF4264 PF14084.6 KKK42972.1 - 0.051 13.2 2.2 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Lactamase_B PF00753.27 KKK42972.1 - 0.19 11.7 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily POR PF01558.18 KKK42973.1 - 3.4e-34 118.5 0.0 4e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 KKK42974.1 - 6.7e-26 90.9 0.0 3e-25 88.8 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 KKK42974.1 - 1.8e-13 50.8 0.0 3.9e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fer4_10 PF13237.6 KKK42974.1 - 3.8e-06 26.9 8.9 0.0058 16.7 1.6 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK42974.1 - 8.6e-06 25.4 9.2 0.00036 20.2 3.2 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK42974.1 - 1.2e-05 25.1 10.0 8.8e-05 22.4 1.1 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK42974.1 - 0.0001 22.4 5.1 0.00026 21.1 5.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK42974.1 - 0.00022 21.3 6.5 0.00053 20.1 6.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK42974.1 - 0.00032 20.6 10.8 0.01 15.8 1.8 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK42974.1 - 0.0019 18.7 6.6 0.0099 16.5 6.9 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK42974.1 - 0.0053 17.2 6.7 0.011 16.1 6.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain DXP_synthase_N PF13292.6 KKK42974.1 - 0.014 14.7 0.4 0.092 11.9 0.6 2.2 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Fer4_16 PF13484.6 KKK42974.1 - 0.037 14.9 7.6 0.17 12.8 7.2 2.3 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain DUF3452 PF11934.8 KKK42974.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Bmp PF02608.14 KKK42974.1 - 0.07 12.1 1.5 1.1 8.2 0.0 2.7 3 0 0 3 3 3 0 ABC transporter substrate-binding protein PnrA-like Fer4_17 PF13534.6 KKK42974.1 - 0.44 11.1 9.2 0.87 10.2 1.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK42974.1 - 1.4 9.8 5.4 4 8.3 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 KKK42974.1 - 2.6 8.7 11.1 0.13 12.8 2.2 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain HSP20 PF00011.21 KKK42975.1 - 3.5e-09 36.7 0.3 2.1e-07 31.0 0.3 2.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKK42975.1 - 2.6e-06 26.9 0.2 1.6e-05 24.4 0.2 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA MFS_1 PF07690.16 KKK42976.1 - 2.7e-16 59.5 44.0 5.1e-14 52.0 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3089 PF11288.8 KKK42977.1 - 0.19 11.2 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PIG-P PF08510.12 KKK42979.1 - 0.041 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 PIG-P zf-ribbon_3 PF13248.6 KKK42980.1 - 5e-05 22.6 1.4 5e-05 22.6 1.4 2.2 3 0 0 3 3 2 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK42980.1 - 0.00048 20.8 14.4 0.033 14.9 9.4 2.7 1 1 1 2 2 2 2 zinc-ribbon family DZR PF12773.7 KKK42980.1 - 0.002 18.1 11.1 0.062 13.3 6.3 3.1 1 1 1 2 2 2 1 Double zinc ribbon SpoIIIAH PF12685.7 KKK42980.1 - 0.0051 16.7 0.1 0.0065 16.3 0.1 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein zinc_ribbon_2 PF13240.6 KKK42980.1 - 0.0064 16.2 2.7 0.0064 16.2 2.7 2.6 3 0 0 3 3 2 1 zinc-ribbon domain Prok-RING_4 PF14447.6 KKK42980.1 - 0.0073 16.1 10.0 0.034 14.0 2.7 3.5 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KKK42980.1 - 0.011 15.6 8.6 0.099 12.5 0.7 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NEMP PF10225.9 KKK42980.1 - 0.028 14.1 0.3 0.032 13.9 0.3 1.1 1 0 0 1 1 1 0 NEMP family E3_UbLigase_R4 PF13764.6 KKK42980.1 - 0.032 12.4 1.9 0.044 11.9 1.9 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 zf-RING_2 PF13639.6 KKK42980.1 - 0.12 12.7 6.8 2.7 8.4 1.0 3.2 3 0 0 3 3 3 0 Ring finger domain BIR PF00653.21 KKK42980.1 - 0.22 12.2 5.6 16 6.2 0.0 3.5 3 1 0 3 3 3 0 Inhibitor of Apoptosis domain zf-LITAF-like PF10601.9 KKK42980.1 - 0.24 11.7 6.8 1 9.7 0.1 2.9 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain O-antigen_lig PF13425.6 KKK42980.1 - 0.27 10.0 2.2 0.32 9.7 2.2 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FancD2 PF14631.6 KKK42980.1 - 0.34 8.2 3.9 0.38 8.1 3.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zf-RING_5 PF14634.6 KKK42980.1 - 0.35 10.9 10.4 0.92 9.5 1.8 3.2 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KKK42980.1 - 0.49 10.3 9.4 5.6 6.9 2.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.15 KKK42980.1 - 0.69 10.0 8.8 2.9 8.0 1.1 3.2 3 0 0 3 3 3 0 BED zinc finger zf-C3HC4 PF00097.25 KKK42980.1 - 0.9 9.5 9.5 5.3 7.0 2.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.15 KKK42980.1 - 1.4 8.6 9.6 0.89 9.2 1.1 3.1 3 0 0 3 3 3 0 RecR protein C1_1 PF00130.22 KKK42980.1 - 1.6 8.7 10.0 3.7 7.5 2.4 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4366 PF14283.6 KKK42980.1 - 2.2 8.3 7.4 8.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) zf-Di19 PF05605.12 KKK42980.1 - 2.2 8.6 9.0 15 6.0 1.1 3.9 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.12 KKK42980.1 - 3.5 7.2 9.2 3.7 7.2 0.3 3.5 2 1 1 3 3 3 0 TFIIB zinc-binding C1_2 PF03107.16 KKK42980.1 - 4 7.8 10.6 1.4 9.3 2.9 2.8 3 0 0 3 3 3 0 C1 domain DUF2321 PF10083.9 KKK42980.1 - 5.7 6.5 9.8 0.31 10.7 1.6 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-dskA_traR PF01258.17 KKK42980.1 - 6.3 6.8 12.5 1.6 8.8 0.2 3.8 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger DUF2116 PF09889.9 KKK42980.1 - 7.1 6.7 10.7 5.6 7.0 0.3 3.3 3 1 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) A2L_zn_ribbon PF08792.10 KKK42980.1 - 7.8 6.3 11.3 38 4.1 5.4 3.1 2 1 0 2 2 2 0 A2L zinc ribbon domain UPF0004 PF00919.20 KKK42981.1 - 2.9e-16 59.3 0.0 5.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 KKK42981.1 - 7e-16 59.0 0.0 1.4e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily TRAM_2 PF18693.1 KKK42981.1 - 0.011 15.8 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 TRAM domain TRAM PF01938.20 KKK42981.1 - 0.017 15.1 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 TRAM domain DUF4184 PF13803.6 KKK42982.1 - 8.2e-21 74.7 0.3 1e-20 74.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4184) YdjM PF04307.14 KKK42982.1 - 3.2e-09 36.4 1.4 4.4e-09 35.9 1.4 1.2 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase Zn_dep_PLPC PF00882.18 KKK42982.1 - 5.3e-05 23.3 0.0 7.7e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Zinc dependent phospholipase C Abhydrolase_1 PF00561.20 KKK42983.1 - 1e-19 71.2 0.0 5.3e-19 68.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK42983.1 - 4.2e-11 43.9 0.0 5.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK42983.1 - 1.2e-07 31.3 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 tRNA-synt_2c PF01411.19 KKK42984.1 - 3.5e-16 58.8 0.1 6.2e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 KKK42984.1 - 9.4e-07 29.3 0.3 1.5e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 KKK42984.1 - 7e-05 22.8 0.4 7e-05 22.8 0.4 2.0 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain GAT PF03127.14 KKK42984.1 - 0.17 12.2 4.1 13 6.2 0.1 3.0 3 0 0 3 3 3 0 GAT domain GCOM2 PF15328.6 KKK42984.1 - 1.1 9.6 5.9 0.4 11.0 1.4 2.2 3 0 0 3 3 3 0 Putative GRINL1B complex locus protein 2 CCG PF02754.16 KKK42985.1 - 1.2e-11 44.7 0.1 1.7e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich domain FNIP PF05725.12 KKK42989.1 - 0.054 13.7 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 FNIP Repeat Propeptide_C1 PF08127.13 KKK42989.1 - 0.074 13.0 0.1 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Peptidase family C1 propeptide Whi5 PF08528.11 KKK42989.1 - 0.38 10.4 4.6 11 5.8 0.0 3.8 4 0 0 4 4 4 0 Whi5 like Pribosyltran PF00156.27 KKK42990.1 - 3.2e-13 49.5 0.0 7.7e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKK42990.1 - 0.00042 19.8 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF1877 PF08974.10 KKK42992.1 - 0.15 12.1 0.2 0.73 9.9 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1877) Phage_Gp19 PF09355.10 KKK42993.1 - 0.015 15.7 0.8 0.025 15.0 0.8 1.2 1 0 0 1 1 1 0 Phage protein Gp19/Gp15/Gp42 DUF4259 PF14078.6 KKK42993.1 - 0.088 13.6 0.4 0.13 13.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) H2O2_YaaD PF03883.14 KKK42994.1 - 6.7e-06 25.8 0.0 1.2e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 Peroxide stress protein YaaA Bcr-Abl_Oligo PF09036.10 KKK42995.1 - 0.022 14.8 0.1 0.062 13.3 0.1 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Rrf2 PF02082.20 KKK42995.1 - 0.028 14.7 0.2 0.094 13.1 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator HrcA_DNA-bdg PF03444.15 KKK42995.1 - 0.029 14.0 0.7 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding NEXCaM_BD PF16644.5 KKK42995.1 - 0.03 14.6 0.2 0.066 13.5 0.2 1.6 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin HTH_20 PF12840.7 KKK42995.1 - 0.036 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_rep_org_N PF09681.10 KKK42995.1 - 0.048 13.6 1.1 0.098 12.6 0.1 1.9 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) TrmB PF01978.19 KKK42995.1 - 0.061 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB zf-RING_13 PF17977.1 KKK42995.1 - 0.07 13.3 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TipAS PF07739.13 KKK42995.1 - 0.14 12.7 0.5 0.74 10.4 0.0 2.3 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain ArfGap PF01412.18 KKK42995.1 - 0.79 9.8 2.9 5.2 7.2 0.3 2.5 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf PALP PF00291.25 KKK43000.1 - 1.4e-27 96.9 0.0 2.8e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NIR_SIR PF01077.22 KKK43001.1 - 6.7e-41 139.5 0.1 9.5e-36 122.7 0.1 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KKK43001.1 - 4.1e-30 103.4 0.0 1.2e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain TusA PF01206.17 KKK43002.1 - 2.1e-18 65.9 0.1 2.6e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 KKK43002.1 - 0.00039 20.2 0.2 0.00064 19.5 0.2 1.4 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2249) Radical_SAM PF04055.21 KKK43003.1 - 1e-19 71.5 0.0 1.7e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK43003.1 - 1.6e-11 44.7 0.0 3.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK43003.1 - 6e-07 29.6 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 KKK43003.1 - 0.0012 19.4 1.6 0.002 18.6 0.2 2.2 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain TP_methylase PF00590.20 KKK43004.1 - 1.9e-45 155.4 0.0 3.2e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases HEM4 PF02602.15 KKK43004.1 - 3.1e-24 85.6 0.0 4.5e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Porphobil_deam PF01379.20 KKK43005.1 - 1.8e-76 256.2 0.0 2.3e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KKK43005.1 - 3.3e-14 53.0 0.0 7.5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain SBP_bac_3 PF00497.20 KKK43005.1 - 0.044 13.2 0.0 0.091 12.2 0.0 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 GlutR_N PF05201.15 KKK43006.1 - 3.1e-32 111.4 0.0 6.3e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 KKK43006.1 - 1.2e-31 109.6 0.6 5.6e-31 107.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 KKK43006.1 - 1.9e-15 57.1 0.4 4.5e-15 55.9 0.4 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain NAD_binding_7 PF13241.6 KKK43006.1 - 0.00017 22.0 0.1 0.0015 18.9 0.0 2.5 3 0 0 3 3 3 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KKK43006.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 KKK43006.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_10 PF13460.6 KKK43006.1 - 0.13 12.2 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H-binding AsnC_trans_reg2 PF17805.1 KKK43007.1 - 2.5e-27 94.8 0.6 5.2e-27 93.8 0.1 1.8 2 0 0 2 2 2 1 AsnC-like ligand binding domain NAD_binding_7 PF13241.6 KKK43007.1 - 7.7e-22 77.7 0.0 1.9e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding DUF2250 PF10007.9 KKK43007.1 - 5.8e-05 23.1 0.1 0.12 12.5 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2250) Sirohm_synth_M PF14824.6 KKK43007.1 - 0.00011 21.6 0.1 0.00035 20.0 0.0 2.0 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central MarR_2 PF12802.7 KKK43007.1 - 0.0021 17.9 0.1 0.0062 16.4 0.1 1.7 2 0 0 2 2 2 1 MarR family AsnC_trans_reg PF01037.21 KKK43007.1 - 0.039 13.9 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain TrkA_N PF02254.18 KKK43007.1 - 0.074 13.3 0.0 0.37 11.1 0.0 2.3 1 1 0 1 1 1 0 TrkA-N domain HTH_Crp_2 PF13545.6 KKK43007.1 - 0.098 12.7 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 KKK43007.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 MarR family AsnC_trans_reg2 PF17805.1 KKK43008.1 - 3.2e-20 72.1 0.0 6e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 AsnC-like ligand binding domain HTH_24 PF13412.6 KKK43008.1 - 5.6e-08 32.2 0.3 1.2e-07 31.2 0.3 1.6 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK43008.1 - 9.2e-07 28.6 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_36 PF13730.6 KKK43008.1 - 5.8e-05 23.0 0.0 8.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain LexA_DNA_bind PF01726.16 KKK43008.1 - 0.00028 20.6 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 LexA DNA binding domain MarR_2 PF12802.7 KKK43008.1 - 0.0033 17.3 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 KKK43008.1 - 0.0042 17.2 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC RuvB_C PF05491.13 KKK43008.1 - 0.013 15.4 1.2 0.13 12.2 0.0 2.5 2 1 1 3 3 3 0 RuvB C-terminal winged helix domain TrmB PF01978.19 KKK43008.1 - 0.014 15.3 0.1 0.071 13.0 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 KKK43008.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 KKK43008.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 KKK43008.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 MarR family Sigma70_r4_2 PF08281.12 KKK43008.1 - 0.024 14.3 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DDRGK PF09756.9 KKK43008.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 DDRGK domain HTH_27 PF13463.6 KKK43008.1 - 0.028 14.9 0.0 0.048 14.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain IF2_N PF04760.15 KKK43008.1 - 0.031 14.1 0.0 0.097 12.5 0.0 1.9 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region PCI PF01399.27 KKK43008.1 - 0.071 13.6 0.1 0.55 10.8 0.0 2.2 1 1 2 3 3 3 0 PCI domain DUF4423 PF14394.6 KKK43008.1 - 0.084 12.6 0.1 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) Radical_SAM PF04055.21 KKK43009.1 - 3.7e-22 79.5 0.1 7.6e-22 78.5 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 KKK43009.1 - 8.6e-10 39.0 1.3 2.3e-09 37.6 1.3 1.8 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 KKK43009.1 - 3.6e-09 37.0 0.0 8.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK43009.1 - 3.3e-08 33.7 0.0 1.7e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain AP_endonuc_2 PF01261.24 KKK43009.1 - 0.07 12.6 0.0 0.35 10.3 0.0 2.0 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Aminotran_3 PF00202.21 KKK43010.1 - 2.1e-70 237.5 0.0 2.5e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ALAD PF00490.21 KKK43011.1 - 1.7e-146 487.4 0.0 1.9e-146 487.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HTH_AsnC-type PF13404.6 KKK43012.1 - 1.1e-16 60.3 0.5 2.7e-16 59.1 0.5 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK43012.1 - 2.4e-15 55.8 0.7 2.4e-15 55.8 0.7 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 KKK43012.1 - 3.6e-07 30.0 0.2 1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain Sigma70_r4_2 PF08281.12 KKK43012.1 - 5.3e-06 26.0 0.0 9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 KKK43012.1 - 0.00012 21.6 0.1 0.00031 20.2 0.1 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 KKK43012.1 - 0.00031 20.6 0.2 0.00088 19.2 0.2 1.8 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 KKK43012.1 - 0.0004 20.4 0.0 0.001 19.0 0.0 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 KKK43012.1 - 0.00051 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 KKK43012.1 - 0.00061 19.9 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KKK43012.1 - 0.00075 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_5 PF01022.20 KKK43012.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 KKK43012.1 - 0.0031 17.4 0.1 0.0083 16.0 0.1 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 KKK43012.1 - 0.0042 17.5 0.1 0.01 16.3 0.1 1.6 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 KKK43012.1 - 0.0043 16.9 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 MarR family CENP-B_N PF04218.13 KKK43012.1 - 0.0054 16.3 0.5 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KKK43012.1 - 0.0061 16.3 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KKK43012.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 MarR family AsnC_trans_reg2 PF17805.1 KKK43012.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.5 2 0 0 2 2 2 0 AsnC-like ligand binding domain Fe_dep_repress PF01325.19 KKK43012.1 - 0.043 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 KKK43012.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Terminase_5 PF06056.12 KKK43012.1 - 0.09 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Hexapep PF00132.24 KKK43013.1 - 9.6e-13 47.3 12.9 8.7e-08 31.6 3.0 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK43013.1 - 0.0019 17.9 18.7 0.007 16.1 1.5 3.8 4 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 KKK43013.1 - 0.0022 18.4 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Abhydrolase_1 PF00561.20 KKK43014.1 - 8.2e-29 101.0 0.0 1.1e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold MetW PF07021.12 KKK43015.1 - 7.1e-53 179.1 0.0 7.9e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KKK43015.1 - 1.2e-10 41.4 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK43015.1 - 2e-10 40.7 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK43015.1 - 2.3e-09 37.8 0.0 3.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK43015.1 - 6.7e-09 36.3 0.0 1e-08 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK43015.1 - 1.2e-07 32.4 0.0 2.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK43015.1 - 0.002 17.5 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KKK43015.1 - 0.003 17.5 0.0 0.0054 16.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KKK43015.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KKK43015.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AdoMet_MTase PF07757.13 KKK43015.1 - 0.038 14.3 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KKK43015.1 - 0.062 13.3 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KKK43015.1 - 0.07 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Aminotran_5 PF00266.19 KKK43016.1 - 3.4e-26 92.1 0.0 4.3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 KKK43016.1 - 0.0013 17.5 0.1 0.0019 17.0 0.1 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS T4_gp9_10 PF07880.11 KKK43016.1 - 0.022 14.4 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein Aminotran_1_2 PF00155.21 KKK43016.1 - 0.029 13.5 0.0 0.075 12.2 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II CtsR PF05848.11 KKK43016.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 CtsR N-terminal HTH domain HTH_AsnC-type PF13404.6 KKK43017.1 - 4.4e-06 26.4 0.1 2.4e-05 24.0 0.1 2.0 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK43017.1 - 4.5e-06 26.1 0.4 0.0045 16.5 0.1 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 KKK43017.1 - 0.034 14.1 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain RecQ_Zn_bind PF16124.5 KKK43017.1 - 0.036 14.8 1.0 0.35 11.6 0.5 2.7 3 0 0 3 3 3 0 RecQ zinc-binding Linocin_M18 PF04454.12 KKK43017.1 - 0.073 12.3 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Med26 PF08711.11 KKK43017.1 - 0.1 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 TFIIS helical bundle-like domain ANAPC5 PF12862.7 KKK43017.1 - 0.13 12.3 0.0 1 9.5 0.0 2.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 HTH_24 PF13412.6 KKK43018.1 - 7.2e-07 28.7 0.3 0.0016 18.0 0.1 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK43018.1 - 2.6e-06 27.2 0.0 1.1e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain DUF3658 PF12395.8 KKK43018.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function AsnC_trans_reg PF01037.21 KKK43018.1 - 0.049 13.6 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Linocin_M18 PF04454.12 KKK43018.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Encapsulating protein for peroxidase eIF-1a PF01176.19 KKK43020.1 - 1.4e-16 60.0 2.7 2.1e-16 59.5 2.7 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Spt5-NGN PF03439.13 KKK43021.1 - 1.5e-13 50.4 0.1 5e-13 48.8 0.0 2.0 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section NusG PF02357.19 KKK43021.1 - 0.081 13.4 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Transcription termination factor nusG Mon1 PF03164.14 KKK43022.1 - 6.4e-05 22.2 4.1 8.1e-05 21.9 4.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 RPAP3_C PF13877.6 KKK43022.1 - 0.0013 19.2 4.5 0.12 12.9 0.3 3.0 1 1 1 2 2 2 2 Potential Monad-binding region of RPAP3 EnY2 PF10163.9 KKK43022.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 Acyl-CoA_dh_1 PF00441.24 KKK43023.1 - 2e-19 70.3 0.1 3.5e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK43023.1 - 1e-11 44.8 0.0 2.5e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK43023.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 KKK43024.1 - 1.1e-19 71.1 0.0 1.8e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK43024.1 - 2.7e-12 46.7 0.0 5.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MAP65_ASE1 PF03999.12 KKK43025.1 - 0.023 13.5 5.4 0.024 13.3 5.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Fijivirus_P9-2 PF06837.11 KKK43025.1 - 0.023 14.2 0.5 0.025 14.1 0.5 1.0 1 0 0 1 1 1 0 Fijivirus P9-2 protein GIT_CC PF16559.5 KKK43025.1 - 0.039 13.8 3.3 0.22 11.4 0.3 2.2 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1815 PF08844.10 KKK43025.1 - 0.043 13.8 0.2 0.056 13.4 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1815) HSBP1 PF06825.12 KKK43025.1 - 0.061 13.2 2.4 0.22 11.4 0.1 2.3 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Laminin_II PF06009.12 KKK43025.1 - 0.066 13.2 4.2 0.1 12.6 4.2 1.4 1 1 0 1 1 1 0 Laminin Domain II DUF241 PF03087.14 KKK43025.1 - 0.21 11.4 7.6 0.23 11.3 7.6 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function BRI3BP PF14965.6 KKK43025.1 - 0.22 11.0 0.4 0.28 10.7 0.4 1.2 1 1 0 1 1 1 0 Negative regulator of p53/TP53 Prefoldin_2 PF01920.20 KKK43025.1 - 0.23 11.5 12.8 0.39 10.7 2.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit Allexi_40kDa PF05549.11 KKK43025.1 - 0.24 10.9 2.6 0.25 10.8 2.6 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein ABC_tran_CTD PF16326.5 KKK43025.1 - 0.55 10.5 12.2 0.56 10.5 4.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain DASH_Dam1 PF08653.10 KKK43025.1 - 0.63 9.9 2.7 10 6.0 0.4 2.2 1 1 1 2 2 2 0 DASH complex subunit Dam1 Prefoldin PF02996.17 KKK43025.1 - 0.96 9.4 10.5 2.8 7.9 2.7 2.1 1 1 1 2 2 2 0 Prefoldin subunit Spc24 PF08286.11 KKK43025.1 - 1.3 9.3 10.1 1.4 9.2 1.4 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Ax_dynein_light PF10211.9 KKK43025.1 - 1.4 8.8 11.7 2.9 7.8 2.9 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain bZIP_2 PF07716.15 KKK43025.1 - 1.4 9.0 11.5 1 9.5 1.2 2.1 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 KKK43025.1 - 2 8.6 9.4 3.9 7.6 1.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor XhlA PF10779.9 KKK43025.1 - 2 8.7 8.8 13 6.1 5.2 2.1 1 1 1 2 2 2 0 Haemolysin XhlA Ras PF00071.22 KKK43026.1 - 2.7e-37 127.9 0.8 1.3e-24 86.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK43026.1 - 1.2e-25 90.1 0.3 9.9e-14 51.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK43026.1 - 2.4e-11 43.4 0.1 1e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK43026.1 - 1.8e-05 24.7 0.0 0.003 17.6 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 KKK43026.1 - 6.4e-05 22.4 0.6 9e-05 21.9 0.1 1.6 2 0 0 2 2 2 1 Septin Gtr1_RagA PF04670.12 KKK43026.1 - 0.00012 21.5 0.1 0.0051 16.2 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK43026.1 - 0.00033 20.6 0.0 0.062 13.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 KKK43026.1 - 0.00098 19.1 1.5 0.029 14.3 0.5 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KKK43026.1 - 0.0022 18.0 0.6 0.0059 16.6 0.3 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK43026.1 - 0.0059 16.1 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 KKK43026.1 - 0.015 15.0 0.1 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KKK43026.1 - 0.024 14.7 0.4 0.057 13.5 0.1 1.8 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 KKK43026.1 - 0.031 13.8 0.1 0.39 10.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B PPL4 PF18188.1 KKK43026.1 - 0.033 14.1 0.2 0.057 13.4 0.2 1.3 1 0 0 1 1 1 0 Prim-pol 4 TniB PF05621.11 KKK43026.1 - 0.036 13.5 0.1 0.084 12.3 0.1 1.7 2 0 0 2 2 2 0 Bacterial TniB protein NB-ARC PF00931.22 KKK43026.1 - 0.037 13.2 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 KKK43026.1 - 0.039 13.1 6.1 0.091 11.9 1.3 2.8 1 1 0 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 KKK43026.1 - 0.044 14.3 0.0 0.093 13.2 0.0 1.5 2 0 0 2 2 1 0 ABC transporter AAA PF00004.29 KKK43026.1 - 0.048 14.1 0.2 1.2 9.6 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK43026.1 - 0.053 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 KKK43026.1 - 0.061 13.1 0.5 8.1 6.1 0.1 2.8 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KKK43026.1 - 0.067 13.5 0.0 0.75 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKK43026.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4139 PF13598.6 KKK43027.1 - 0.014 15.1 1.6 0.029 14.1 1.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4139) NAD_binding_2 PF03446.15 KKK43027.1 - 0.024 14.8 0.0 0.093 12.9 0.0 1.9 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fib_alpha PF08702.10 KKK43027.1 - 0.13 12.4 10.6 0.46 10.7 10.6 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KKK43027.1 - 0.65 10.1 11.1 1.9 8.5 11.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 KKK43027.1 - 0.87 9.8 13.5 0.62 10.3 2.8 3.0 2 0 0 2 2 2 0 Haemolysin XhlA Exonuc_VII_L PF02601.15 KKK43027.1 - 1 8.9 3.7 1.8 8.0 3.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Uds1 PF15456.6 KKK43027.1 - 1.6 8.9 6.7 8.7 6.5 6.7 2.2 1 1 0 1 1 1 0 Up-regulated During Septation Helo_like_N PF17111.5 KKK43027.1 - 2.6 7.3 10.3 2.8 7.2 1.1 2.4 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Thioredoxin_9 PF14595.6 KKK43029.1 - 7.7e-13 48.3 0.0 4.4e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin PF00085.20 KKK43029.1 - 0.0002 21.3 0.1 0.06 13.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KKK43029.1 - 0.0031 17.9 0.0 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain DUF953 PF06110.11 KKK43029.1 - 0.0044 16.6 0.1 0.0084 15.7 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.6 KKK43029.1 - 0.011 16.0 0.5 0.34 11.3 0.0 2.8 1 1 1 2 2 2 0 Thioredoxin-like MqsA_antitoxin PF15731.5 KKK43029.1 - 0.023 14.8 0.0 6.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DUF929 PF06053.11 KKK43029.1 - 0.06 12.7 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) AFOR_C PF01314.18 KKK43030.1 - 3.1e-88 296.4 0.0 5.9e-88 295.4 0.0 1.4 2 0 0 2 2 2 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK43030.1 - 1.1e-54 185.4 0.8 1.9e-54 184.5 0.8 1.4 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Ras PF00071.22 KKK43031.1 - 1.4e-45 154.8 0.1 1.6e-45 154.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK43031.1 - 3.4e-28 98.3 0.0 4.6e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK43031.1 - 8.2e-15 54.7 0.1 9.2e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK43031.1 - 3.5e-06 26.6 0.0 4.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK43031.1 - 3.5e-05 23.3 0.1 3.9e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK43031.1 - 9.7e-05 22.0 0.1 0.017 14.6 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK43031.1 - 0.00094 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KKK43031.1 - 0.0024 17.6 0.5 0.014 15.2 0.4 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KKK43031.1 - 0.027 14.2 0.2 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KKK43031.1 - 0.034 14.5 0.0 0.063 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KKK43031.1 - 0.04 14.0 0.0 0.091 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KKK43031.1 - 0.047 13.0 0.1 1.2 8.3 0.1 2.1 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 KKK43031.1 - 0.051 13.8 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mito_fiss_Elm1 PF06258.11 KKK43031.1 - 0.059 12.5 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 ATPase_2 PF01637.18 KKK43031.1 - 0.081 12.8 0.1 0.24 11.3 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 KKK43031.1 - 0.097 12.1 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein MobB PF03205.14 KKK43031.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Radical_SAM PF04055.21 KKK43032.1 - 3.9e-10 40.4 0.1 1.6e-09 38.4 0.1 1.9 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KKK43032.1 - 9.2e-06 25.8 0.2 3.7e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK43032.1 - 7.9e-05 23.0 0.4 0.0007 19.9 0.1 2.4 3 0 0 3 3 3 1 4Fe-4S single cluster domain DUF5637 PF18687.1 KKK43032.1 - 0.014 15.4 2.7 0.03 14.3 2.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5637) ACT PF01842.25 KKK43033.1 - 2.8e-08 33.4 0.3 0.0034 17.1 0.0 2.2 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 KKK43033.1 - 0.0079 16.8 0.1 0.51 11.0 0.0 2.2 2 0 0 2 2 2 2 ACT domain PIN PF01850.21 KKK43034.1 - 3.1e-12 47.1 0.4 3.8e-12 46.8 0.4 1.1 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 KKK43034.1 - 0.0031 18.3 0.0 0.0038 18.0 0.0 1.3 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KKK43034.1 - 0.017 15.6 3.0 0.025 15.0 3.0 1.4 1 1 0 1 1 1 0 PIN domain RHH_1 PF01402.21 KKK43035.1 - 0.016 15.1 0.8 0.3 11.1 0.8 2.5 1 1 0 1 1 1 0 Ribbon-helix-helix protein, copG family DUF3333 PF11812.8 KKK43035.1 - 0.017 15.3 0.1 0.019 15.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) RHH_3 PF12651.7 KKK43035.1 - 0.043 13.8 0.3 1.3 9.0 0.3 2.4 1 1 0 1 1 1 0 Ribbon-helix-helix domain DUF1998 PF09369.10 KKK43036.1 - 3.4e-18 66.2 0.1 7.5e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KKK43036.1 - 1.8e-11 44.4 0.1 6.5e-11 42.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KKK43036.1 - 3.6e-06 26.8 0.0 5.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase UPF0020 PF01170.18 KKK43039.1 - 0.0092 15.7 0.0 0.077 12.7 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KKK43039.1 - 0.023 14.4 0.0 0.24 11.1 0.0 2.3 2 1 0 2 2 2 0 DNA methylase DUF4159 PF13709.6 KKK43040.1 - 0.00036 20.0 0.0 0.00064 19.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) Glyco_hydro_42M PF08532.10 KKK43040.1 - 0.0016 17.9 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain GATase1_like PF07090.11 KKK43040.1 - 0.0047 16.4 0.0 0.36 10.2 0.0 2.4 2 0 0 2 2 2 1 Putative glutamine amidotransferase ABC_transp_aux PF09822.9 KKK43040.1 - 0.0055 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Nop25 PF09805.9 KKK43040.1 - 0.034 14.6 2.3 0.057 13.9 2.3 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) ThuA PF06283.11 KKK43040.1 - 0.065 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation Met_10 PF02475.16 KKK43041.1 - 2.1e-54 184.3 0.0 2.6e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 KKK43041.1 - 3.1e-05 23.6 0.0 4.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KKK43041.1 - 0.00051 19.5 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KKK43041.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK43041.1 - 0.0024 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KKK43041.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TRM PF02005.16 KKK43041.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase AMP-binding PF00501.28 KKK43042.1 - 2.8e-73 247.0 0.0 3.7e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK43042.1 - 1.7e-13 51.4 0.2 3.8e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LOR PF04525.12 KKK43044.1 - 4e-11 42.9 1.7 5.8e-11 42.3 1.7 1.2 1 0 0 1 1 1 1 LURP-one-related Scramblase PF03803.15 KKK43044.1 - 0.00037 19.9 0.3 0.025 13.9 0.1 2.0 1 1 1 2 2 2 2 Scramblase UPF0113_N PF17833.1 KKK43044.1 - 0.12 13.0 2.0 0.56 10.8 1.7 2.4 1 1 0 1 1 1 0 UPF0113 Pre-PUA domain Succ_CoA_lig PF13607.6 KKK43045.1 - 1.7e-36 125.1 0.0 1.7e-35 121.8 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK43045.1 - 7e-18 65.2 0.0 1.4e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK43045.1 - 8e-08 32.9 0.1 1.8e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain NMO PF03060.15 KKK43046.1 - 3.2e-46 158.2 0.5 6.4e-46 157.3 0.5 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KKK43046.1 - 1.2e-08 34.4 1.2 2.3e-08 33.5 1.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK43046.1 - 1.9e-07 30.4 3.1 0.004 16.2 0.0 2.9 2 2 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain DUF1729 PF08354.10 KKK43046.1 - 0.093 11.6 0.2 0.38 9.6 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) FGGY_N PF00370.21 KKK43047.1 - 1.8e-39 135.8 0.0 4.3e-39 134.5 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KKK43047.1 - 2e-20 73.3 0.0 4.3e-20 72.3 0.0 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Phytochelatin_C PF09328.10 KKK43047.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) TPR_2 PF07719.17 KKK43049.1 - 0.047 13.8 0.1 0.08 13.1 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Vps26 PF03643.15 KKK43049.1 - 0.048 12.7 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 BAR_3 PF16746.5 KKK43049.1 - 0.069 12.9 0.4 0.098 12.4 0.4 1.1 1 0 0 1 1 1 0 BAR domain of APPL family Exo70 PF03081.15 KKK43052.1 - 0.047 12.7 0.3 0.047 12.7 0.3 2.0 2 1 1 3 3 3 0 Exo70 exocyst complex subunit Lar_restr_allev PF14354.6 KKK43053.1 - 0.0036 17.6 0.1 0.0042 17.4 0.1 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.6 KKK43053.1 - 0.025 14.5 0.7 4.2 7.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.13 KKK43053.1 - 0.033 14.2 0.2 0.041 13.9 0.2 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 KKK43053.1 - 0.047 13.7 0.8 0.096 12.7 0.8 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-trcl PF13451.6 KKK43053.1 - 0.14 12.0 2.5 1.8 8.5 0.1 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain zinc_ribbon_9 PF14369.6 KKK43053.1 - 0.17 12.1 1.1 0.17 12.1 1.1 1.9 1 1 1 2 2 2 0 zinc-ribbon GTP_EFTU PF00009.27 KKK43054.1 - 1.4e-25 90.0 3.3 1.6e-25 89.8 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 KKK43054.1 - 6.9e-18 64.7 0.0 1.8e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal HHH_5 PF14520.6 KKK43054.1 - 6e-10 39.6 3.2 1.5e-09 38.3 3.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 KKK43054.1 - 1.7e-05 24.4 0.8 0.12 12.3 0.2 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif IMS_HHH PF11798.8 KKK43054.1 - 5.5e-05 23.3 0.1 0.016 15.5 0.0 2.9 2 0 0 2 2 2 1 IMS family HHH motif MMR_HSR1 PF01926.23 KKK43054.1 - 0.0001 22.4 0.0 0.0018 18.3 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Cdd1 PF11731.8 KKK43054.1 - 0.00029 21.0 0.0 0.00094 19.4 0.0 1.8 1 1 0 1 1 1 1 Pathogenicity locus GTP_EFTU_D2 PF03144.25 KKK43054.1 - 0.00029 21.1 2.9 0.00032 21.0 0.7 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KKK43054.1 - 0.00045 20.2 2.0 0.55 10.1 0.9 2.4 2 0 0 2 2 2 2 RsgA GTPase HHH_8 PF14716.6 KKK43054.1 - 0.00096 19.5 1.1 1.6 9.1 0.2 2.8 3 0 0 3 3 2 2 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KKK43054.1 - 0.0014 18.4 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_2 PF12826.7 KKK43054.1 - 0.01 15.9 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4332 PF14229.6 KKK43054.1 - 0.015 15.5 0.2 0.056 13.7 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4332) RNA_pol_A_CTD PF03118.15 KKK43054.1 - 0.017 14.9 0.6 0.038 13.7 0.2 1.9 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain IBR PF01485.21 KKK43054.1 - 0.048 13.9 0.4 0.097 12.9 0.4 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF3173 PF11372.8 KKK43054.1 - 0.093 12.6 0.3 0.27 11.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Adenine_glyco PF03352.13 KKK43054.1 - 0.14 11.9 0.2 0.31 10.8 0.2 1.5 1 0 0 1 1 1 0 Methyladenine glycosylase TFIIS_C PF01096.18 KKK43054.1 - 0.37 10.7 1.6 0.75 9.7 1.6 1.5 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) DpnI PF06044.12 KKK43054.1 - 0.65 9.6 2.8 0.33 10.6 0.3 1.7 2 0 0 2 2 2 0 Dam-replacing family DUF4566 PF15130.6 KKK43055.1 - 0.06 12.8 1.2 0.07 12.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) CarboxypepD_reg PF13620.6 KKK43056.1 - 0.0019 18.4 0.3 0.0048 17.1 0.3 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KKK43056.1 - 0.071 13.1 0.2 0.33 11.0 0.2 2.1 1 1 0 1 1 1 0 CarboxypepD_reg-like domain DHHA1 PF02272.19 KKK43057.1 - 4.5e-07 30.4 0.2 2.5e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 DHHA1 domain DHH PF01368.20 KKK43057.1 - 0.0017 18.6 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 DHH family DUF167 PF02594.16 KKK43058.1 - 1.1e-13 51.1 1.0 1.3e-13 50.8 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 TFIIS_C PF01096.18 KKK43059.1 - 1.1e-13 50.7 0.8 1.1e-13 50.7 0.8 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KKK43059.1 - 2.8e-07 30.3 11.3 0.00014 21.6 3.6 3.2 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 KKK43059.1 - 0.0039 16.8 1.2 0.012 15.3 1.2 1.9 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Cas_Cas4 PF01930.17 KKK43059.1 - 0.021 14.9 1.8 0.021 14.9 1.8 1.4 2 0 0 2 2 2 0 Domain of unknown function DUF83 Tnp_zf-ribbon_2 PF13842.6 KKK43059.1 - 0.28 12.0 6.6 6.2 7.7 2.6 3.3 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Rpr2 PF04032.16 KKK43059.1 - 0.34 11.2 7.0 40 4.6 7.0 2.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf_UBZ PF18439.1 KKK43059.1 - 0.49 10.0 8.3 1.3 8.7 0.1 3.1 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1595 PF12760.7 KKK43059.1 - 1.8 8.6 11.9 7.1 6.7 0.3 3.3 3 1 1 4 4 4 0 Transposase zinc-ribbon domain zf_C2H2_13 PF18508.1 KKK43059.1 - 2 8.1 0.0 2 8.1 0.0 2.9 3 0 0 3 3 3 0 Zinc finger domain CitG PF01874.16 KKK43060.1 - 3e-57 194.4 0.0 3.4e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase Ribosomal_L22e PF01776.17 KKK43061.1 - 6.8e-06 26.4 0.5 9.5e-06 26.0 0.5 1.4 1 1 0 1 1 1 1 Ribosomal L22e protein family DUF2111 PF09884.9 KKK43061.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) RuBisCO_large PF00016.20 KKK43062.1 - 2e-98 329.3 0.5 2.7e-98 328.9 0.5 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RuBisCO_large_N PF02788.16 KKK43062.1 - 1.4e-37 128.5 0.1 3.5e-37 127.2 0.1 1.7 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain IF-2B PF01008.17 KKK43063.1 - 9e-67 225.2 0.2 1e-66 225.0 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1722 PF08349.11 KKK43063.1 - 0.037 14.3 1.9 0.19 12.0 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) EcKinase PF02958.20 KKK43063.1 - 0.04 13.2 0.3 0.06 12.6 0.3 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase ERp29 PF07749.12 KKK43063.1 - 0.054 14.4 0.3 0.11 13.4 0.3 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Snf7 PF03357.21 KKK43063.1 - 0.33 10.5 2.9 0.59 9.7 2.9 1.4 1 0 0 1 1 1 0 Snf7 zf-ribbon_3 PF13248.6 KKK43064.1 - 0.0015 17.9 1.7 0.35 10.3 0.3 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Lar_restr_allev PF14354.6 KKK43064.1 - 0.004 17.5 0.1 0.0052 17.1 0.1 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar DUF2387 PF09526.10 KKK43064.1 - 0.0061 16.7 0.8 0.0089 16.2 0.8 1.4 1 1 0 1 1 1 1 Probable metal-binding protein (DUF2387) Ribosomal_L32p PF01783.23 KKK43064.1 - 0.023 15.0 2.8 3.5 8.0 0.2 2.1 1 1 1 2 2 2 0 Ribosomal L32p protein family IBR PF01485.21 KKK43064.1 - 0.042 14.1 0.6 0.059 13.6 0.6 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 KKK43064.1 - 0.11 12.5 1.7 2 8.4 2.7 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain GIY-YIG PF01541.24 KKK43066.1 - 9.9e-07 29.0 3.6 9.9e-07 29.0 3.6 2.8 3 0 0 3 3 3 1 GIY-YIG catalytic domain UVR PF02151.19 KKK43066.1 - 3.6e-06 26.6 3.4 3.6e-06 26.6 3.4 2.9 3 0 0 3 3 3 1 UvrB/uvrC motif LMP PF04778.12 KKK43066.1 - 0.026 14.5 0.6 0.026 14.5 0.6 2.4 3 0 0 3 3 3 0 LMP repeated region LRR_4 PF12799.7 KKK43069.1 - 1.4e-26 92.1 28.4 1.1e-08 35.2 1.9 4.2 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK43069.1 - 6.4e-17 61.1 20.8 4e-08 32.9 3.2 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 KKK43069.1 - 6.8e-10 38.7 11.5 3.8e-06 26.5 3.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KKK43069.1 - 6.4e-05 23.0 16.3 3.4 8.6 0.9 6.9 5 2 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 KKK43069.1 - 0.00029 20.6 18.6 2 8.7 0.0 7.1 7 0 0 7 7 7 1 Leucine Rich repeat UB2H PF14814.6 KKK43069.1 - 0.033 14.2 1.3 42 4.2 0.0 3.9 2 1 3 5 5 5 0 Bifunctional transglycosylase second domain HTH_25 PF13413.6 KKK43069.1 - 0.11 12.4 0.5 0.74 9.7 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain PDZ_3 PF17815.1 KKK43069.1 - 0.19 11.6 1.8 8.2 6.3 0.1 2.7 1 1 1 2 2 2 0 PDZ domain Arm_3 PF16186.5 KKK43069.1 - 5.5 6.6 18.3 0.42 10.2 0.7 5.0 6 1 1 7 7 7 0 Atypical Arm repeat DUF2120 PF09893.9 KKK43073.1 - 0.041 14.0 0.6 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF420 PF04238.12 KKK43078.1 - 0.29 11.4 5.5 0.32 11.3 2.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF420) Cytochrom_B561 PF03188.16 KKK43078.1 - 0.61 10.2 7.9 0.6 10.2 3.9 2.2 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 Cytochrom_C_asm PF01578.20 KKK43079.1 - 1.6e-25 90.1 14.6 1.6e-25 90.1 14.6 5.1 5 1 0 5 5 5 1 Cytochrome C assembly protein ABC_tran PF00005.27 KKK43080.1 - 2.5e-30 105.8 0.0 3.7e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK43080.1 - 7.8e-18 65.3 3.9 6.9e-12 45.8 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 KKK43080.1 - 1.8e-07 30.2 6.2 4.1e-05 22.5 1.4 2.4 2 1 1 3 3 3 2 AAA domain AAA PF00004.29 KKK43080.1 - 0.00012 22.5 2.4 0.0015 18.9 2.4 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KKK43080.1 - 0.0002 20.9 1.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KKK43080.1 - 0.0026 17.5 14.8 0.0034 17.2 2.5 2.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KKK43080.1 - 0.004 17.7 13.3 0.014 15.9 13.3 1.9 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KKK43080.1 - 0.0057 16.6 0.1 0.021 14.7 0.0 1.7 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 KKK43080.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KKK43080.1 - 0.023 14.9 0.0 0.05 13.9 0.0 1.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KKK43080.1 - 0.03 13.5 0.6 2.2 7.4 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain CbiA PF01656.23 KKK43080.1 - 0.077 13.1 0.3 0.26 11.4 0.3 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KKK43080.1 - 0.25 11.9 1.9 1.2 9.7 1.8 2.2 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KKK43080.1 - 0.34 10.8 0.2 0.34 10.8 0.2 2.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ABC2_membrane_4 PF12730.7 KKK43081.1 - 1.5e-11 44.6 21.6 1.5e-11 44.6 21.6 2.3 1 1 1 2 2 2 2 ABC-2 family transporter protein CcmB PF03379.13 KKK43081.1 - 1.1e-10 41.4 11.0 1.5e-10 41.0 11.0 1.2 1 0 0 1 1 1 1 CcmB protein ABC2_membrane PF01061.24 KKK43081.1 - 1.9e-05 24.2 32.6 0.00016 21.1 32.6 2.1 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 KKK43081.1 - 9.2e-05 21.9 26.7 0.0003 20.2 26.7 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 KKK43081.1 - 0.0054 15.9 47.0 0.017 14.2 47.0 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 KKK43081.1 - 0.023 14.3 45.6 0.059 12.9 45.6 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein CcmE PF03100.15 KKK43082.1 - 7.7e-11 42.1 0.2 1.4e-10 41.2 0.2 1.4 1 1 0 1 1 1 1 CcmE DUF4179 PF13786.6 KKK43082.1 - 0.095 13.2 3.3 0.16 12.4 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Amnionless PF14828.6 KKK43082.1 - 0.18 10.6 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Amnionless CcmD PF04995.14 KKK43083.1 - 0.00061 19.8 0.0 0.0007 19.6 0.0 1.1 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) SDH_sah PF01972.16 KKK43083.1 - 0.0054 15.8 0.6 0.0054 15.8 0.6 1.0 1 0 0 1 1 1 1 Serine dehydrogenase proteinase LapA_dom PF06305.11 KKK43083.1 - 0.009 15.8 0.2 0.012 15.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF2681 PF10883.8 KKK43083.1 - 0.0098 16.3 0.3 0.011 16.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Vpu PF00558.19 KKK43083.1 - 0.33 10.8 4.9 0.35 10.7 4.9 1.1 1 0 0 1 1 1 0 Vpu protein Cytochrom_C_asm PF01578.20 KKK43084.1 - 1.1e-09 38.4 12.8 1.1e-09 38.4 12.8 2.0 2 1 0 2 2 2 1 Cytochrome C assembly protein BCHF PF07284.11 KKK43084.1 - 0.0001 22.3 0.5 0.0001 22.3 0.5 2.3 2 1 1 3 3 3 1 2-vinyl bacteriochlorophyllide hydratase (BCHF) Sid-5 PF17204.3 KKK43084.1 - 2.3 8.5 6.6 20 5.5 0.3 2.6 2 0 0 2 2 2 0 Sid-5 family CbiM PF01891.16 KKK43084.1 - 8 6.2 11.9 0.61 9.9 1.0 2.3 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region LRR_8 PF13855.6 KKK43086.1 - 1.4e-21 76.0 42.3 0.0039 16.9 5.3 8.7 4 1 6 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KKK43086.1 - 1.6e-14 53.7 60.6 0.0096 16.3 0.5 10.9 4 2 6 11 11 11 8 Leucine Rich repeats (2 copies) TPR_1 PF00515.28 KKK43086.1 - 5.4e-07 29.2 9.2 0.0038 17.0 2.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK43086.1 - 1.1e-05 25.2 4.8 0.098 12.9 0.4 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK43086.1 - 2.7e-05 24.0 6.2 0.24 11.6 1.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK43086.1 - 3.9e-05 23.7 4.6 0.23 11.9 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK43086.1 - 0.00017 21.2 0.8 0.0012 18.5 0.2 2.6 2 1 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 KKK43086.1 - 0.0018 18.5 2.2 0.016 15.5 0.2 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 CDKN3 PF05706.12 KKK43086.1 - 0.013 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_12 PF13424.6 KKK43086.1 - 0.017 15.4 0.3 26 5.2 0.0 3.5 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK43086.1 - 0.02 15.4 0.0 0.076 13.5 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK43086.1 - 0.055 13.5 0.1 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK43086.1 - 0.089 13.7 0.0 29 5.8 0.0 3.5 3 1 2 5 5 4 0 Tetratricopeptide repeat Hemopexin PF00045.19 KKK43086.1 - 0.39 10.7 2.9 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Hemopexin APC_r PF05923.12 KKK43086.1 - 1.9 8.3 3.7 5.6 6.8 3.7 1.9 1 0 0 1 1 1 0 APC repeat LRR_1 PF00560.33 KKK43086.1 - 3.3 8.6 62.1 0.54 11.0 3.2 13.9 15 2 0 15 15 13 0 Leucine Rich Repeat DUF420 PF04238.12 KKK43087.1 - 1.2e-13 51.5 8.2 1.4e-13 51.3 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF420) Pox_A14 PF05767.12 KKK43087.1 - 3.1 8.0 9.1 0.36 11.0 2.4 2.4 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF4282 PF14110.6 KKK43087.1 - 7.3 7.4 14.7 2.1 9.1 2.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) HTH_24 PF13412.6 KKK43088.1 - 1.1e-06 28.0 0.3 0.0022 17.5 0.1 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK43088.1 - 7.4e-06 25.7 0.0 3.3e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain DUF3658 PF12395.8 KKK43088.1 - 0.0041 17.0 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function AsnC_trans_reg PF01037.21 KKK43088.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain Linocin_M18 PF04454.12 KKK43088.1 - 0.082 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Encapsulating protein for peroxidase HTH_24 PF13412.6 KKK43089.1 - 4.1e-06 26.2 0.4 0.0045 16.5 0.1 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK43089.1 - 4.5e-06 26.4 0.1 2.4e-05 24.0 0.1 2.0 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KKK43089.1 - 0.0089 16.0 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain ANAPC5 PF12862.7 KKK43089.1 - 0.041 13.9 0.0 0.27 11.3 0.0 2.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 Med26 PF08711.11 KKK43089.1 - 0.1 12.6 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Linocin_M18 PF04454.12 KKK43089.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Aminotran_5 PF00266.19 KKK43090.1 - 4.6e-26 91.6 0.0 5.9e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 KKK43090.1 - 0.0014 17.4 0.1 0.0021 16.8 0.1 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 KKK43090.1 - 0.11 11.6 0.0 0.52 9.4 0.0 2.2 1 1 0 1 1 1 0 Aminotransferase class I and II MetW PF07021.12 KKK43091.1 - 3e-31 108.5 0.2 3.4e-31 108.4 0.2 1.0 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 KKK43091.1 - 0.00096 19.8 0.0 0.0017 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK43091.1 - 0.0035 17.1 0.0 0.006 16.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK43091.1 - 0.023 15.4 0.0 0.053 14.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KKK43091.1 - 0.078 13.7 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.20 KKK43092.1 - 4.1e-29 102.0 0.0 5.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK43092.1 - 0.17 11.3 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hexapep PF00132.24 KKK43093.1 - 3.3e-13 48.8 14.5 4.1e-07 29.5 3.0 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK43093.1 - 0.00051 19.7 17.4 0.007 16.1 1.5 4.0 3 2 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 KKK43093.1 - 0.002 18.5 0.0 0.005 17.2 0.0 1.6 2 0 0 2 2 2 1 Serine acetyltransferase, N-terminal HEM4 PF02602.15 KKK43094.1 - 6.6e-48 163.1 0.0 7.5e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF3343 PF11823.8 KKK43094.1 - 0.02 14.4 0.7 0.37 10.3 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3343) IMS_HHH PF11798.8 KKK43094.1 - 0.067 13.5 0.2 8.7 6.9 0.0 3.2 3 0 0 3 3 3 0 IMS family HHH motif TP_methylase PF00590.20 KKK43095.1 - 2.6e-50 171.3 0.0 3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Delta_lysin PF05372.11 KKK43095.1 - 2.4 7.5 6.0 1.6 8.1 0.8 2.5 2 0 0 2 2 2 0 Delta lysin family Porphobil_deam PF01379.20 KKK43096.1 - 3.7e-69 232.3 0.0 4.6e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KKK43096.1 - 5.8e-19 68.3 0.0 2e-18 66.5 0.0 1.9 1 1 1 2 2 2 1 Porphobilinogen deaminase, C-terminal domain Aminotran_3 PF00202.21 KKK43097.1 - 6e-75 252.4 0.0 7.5e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKK43097.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II ALAD PF00490.21 KKK43098.1 - 2.1e-146 487.1 1.1 2.4e-146 486.9 1.1 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase GlutR_N PF05201.15 KKK43099.1 - 2.7e-36 124.5 0.5 2.7e-35 121.3 0.0 2.2 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 KKK43099.1 - 8.7e-30 103.6 2.9 1.1e-29 103.2 0.4 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 KKK43099.1 - 2.7e-15 56.6 1.7 2.7e-15 56.6 1.7 2.4 3 0 0 3 3 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 KKK43099.1 - 2.6e-06 27.9 0.3 9.2e-06 26.2 0.3 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KKK43099.1 - 0.0002 20.8 0.1 0.00035 20.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KKK43099.1 - 0.00032 21.5 0.1 0.00083 20.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 KKK43099.1 - 0.00076 19.2 0.2 0.0014 18.3 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 KKK43099.1 - 0.0066 15.8 0.2 0.015 14.6 0.2 1.5 1 0 0 1 1 1 1 ThiF family THF_DHG_CYH_C PF02882.19 KKK43099.1 - 0.013 14.8 0.5 0.17 11.2 0.1 2.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KKK43099.1 - 0.013 15.9 0.2 0.056 13.9 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 KKK43099.1 - 0.017 14.7 0.2 0.041 13.5 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 KKK43099.1 - 0.028 14.6 0.0 0.09 12.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KKK43099.1 - 0.071 12.3 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK43099.1 - 0.074 13.6 1.1 0.26 11.9 0.0 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KKK43100.1 - 1.4e-24 86.5 0.0 3.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KKK43100.1 - 3.9e-08 33.5 0.3 8.9e-08 32.3 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KKK43100.1 - 6.4e-07 28.9 0.0 5.7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KKK43100.1 - 4.4e-06 26.9 0.1 1.3e-05 25.5 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 KKK43100.1 - 7.9e-05 22.1 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KKK43100.1 - 0.00012 22.6 0.5 0.00031 21.3 0.1 1.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KKK43100.1 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Sirohm_synth_M PF14824.6 KKK43100.1 - 0.02 14.3 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central AdoHcyase_NAD PF00670.21 KKK43100.1 - 0.023 14.8 0.1 0.05 13.7 0.0 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KKK43100.1 - 0.085 12.4 0.4 0.15 11.7 0.3 1.5 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 KKK43100.1 - 0.091 12.1 0.2 2.6 7.3 0.0 2.4 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA_14 PF13173.6 KKK43100.1 - 0.14 12.2 2.5 0.25 11.4 0.1 2.3 2 1 0 2 2 2 0 AAA domain TFIID_NTD2 PF04494.15 KKK43100.1 - 0.57 10.4 5.6 1.5 9.1 0.3 2.8 2 1 1 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain TusA PF01206.17 KKK43101.1 - 4.8e-18 64.7 0.0 6.3e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 KKK43101.1 - 0.027 14.3 0.0 0.039 13.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) NIR_SIR PF01077.22 KKK43102.1 - 5.4e-45 152.7 0.0 4.2e-39 133.6 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KKK43102.1 - 2.3e-31 107.5 0.0 2.6e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain DGC PF08859.11 KKK43102.1 - 0.0028 17.7 0.1 0.14 12.3 0.1 2.6 2 0 0 2 2 2 1 DGC domain PALP PF00291.25 KKK43103.1 - 2.7e-55 187.8 0.0 4.4e-55 187.2 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TauE PF01925.19 KKK43104.1 - 2.2e-20 73.3 24.8 2.7e-20 73.0 24.8 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE PAPS_reduct PF01507.19 KKK43105.1 - 2.9e-41 141.4 0.0 4.8e-41 140.7 0.0 1.4 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family DUF1923 PF09083.10 KKK43105.1 - 0.022 14.4 0.0 0.071 12.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1923) ATP-sulfurylase PF01747.17 KKK43106.1 - 6.4e-83 277.4 0.0 7.9e-83 277.1 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KKK43106.1 - 1.3e-41 142.0 0.0 2.3e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain N6_Mtase PF02384.16 KKK43109.1 - 4.9e-29 101.6 0.0 7.3e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 KKK43109.1 - 3.1e-06 27.0 0.0 2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 KKK43109.1 - 0.0019 17.8 0.0 1.3 8.5 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase small domain Methyltransf_31 PF13847.6 KKK43109.1 - 0.022 14.5 0.0 0.22 11.3 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Alba PF01918.21 KKK43110.1 - 4.2e-13 48.9 0.2 5.3e-13 48.6 0.2 1.2 1 0 0 1 1 1 1 Alba Methyltransf_31 PF13847.6 KKK43111.1 - 4.4e-20 72.0 0.0 2.4e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK43111.1 - 1.9e-14 54.2 0.0 4.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK43111.1 - 4e-13 49.5 0.0 6.4e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK43111.1 - 3.3e-10 40.5 0.0 5.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK43111.1 - 4.3e-10 40.1 0.0 7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KKK43111.1 - 9.1e-08 31.6 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KKK43111.1 - 3.1e-06 26.8 0.0 6.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KKK43111.1 - 1.6e-05 24.6 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KKK43111.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KKK43111.1 - 0.0046 15.9 0.0 0.0095 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 KKK43111.1 - 0.0075 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Rrf2 PF02082.20 KKK43111.1 - 0.021 15.2 0.0 0.075 13.4 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator CMAS PF02353.20 KKK43111.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KKK43111.1 - 0.055 13.2 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dimerisation2 PF16864.5 KKK43111.1 - 0.091 12.8 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain PrmA PF06325.13 KKK43111.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 KKK43111.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CooT PF10133.9 KKK43112.1 - 5.7e-05 23.3 2.8 5.7e-05 23.3 2.8 1.5 2 0 0 2 2 2 1 CO dehydrogenase accessory protein CooT WHEP-TRS PF00458.20 KKK43112.1 - 0.032 14.4 0.1 0.049 13.8 0.1 1.3 1 0 0 1 1 1 0 WHEP-TRS domain Amidase PF01425.21 KKK43113.1 - 3.8e-116 388.7 0.0 2.3e-115 386.2 0.0 1.8 1 1 0 1 1 1 1 Amidase Amidase PF01425.21 KKK43114.1 - 0.00044 19.3 0.0 0.00055 19.0 0.0 1.2 1 0 0 1 1 1 1 Amidase Nup192 PF11894.8 KKK43114.1 - 0.003 14.8 0.1 0.0034 14.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Cation_ATPase_C PF00689.21 KKK43116.1 - 0.18 11.5 10.0 0.22 11.2 10.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2207 PF09972.9 KKK43116.1 - 4.3 6.0 6.8 5.8 5.6 6.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Lar_N PF09861.9 KKK43117.1 - 7.6e-65 217.9 0.0 1.3e-64 217.1 0.0 1.4 1 0 0 1 1 1 1 Lactate racemase N-terminal domain Glu_synthase PF01645.17 KKK43117.1 - 0.05 12.7 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase GTP-bdg_N PF13167.6 KKK43117.1 - 0.16 12.7 0.2 0.47 11.2 0.1 1.9 2 0 0 2 2 2 0 GTP-binding GTPase N-terminal FAD-oxidase_C PF02913.19 KKK43118.1 - 3e-22 79.5 0.1 4.1e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Fer4_8 PF13183.6 KKK43118.1 - 1.5e-08 35.0 2.7 2.5e-08 34.2 2.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK43118.1 - 2.5e-08 34.3 4.1 4.5e-08 33.5 4.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK43118.1 - 1.4e-05 25.6 2.2 2.9e-05 24.6 2.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43118.1 - 0.00019 21.5 8.8 0.0025 17.9 9.8 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43118.1 - 0.00053 20.1 8.5 0.017 15.2 2.0 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 KKK43118.1 - 0.0015 18.2 1.2 0.0015 18.2 1.2 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 KKK43118.1 - 0.0019 18.3 2.6 0.38 10.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43118.1 - 0.0019 18.2 10.7 0.077 13.1 1.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 KKK43118.1 - 0.0061 16.7 0.3 3.3 8.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43118.1 - 0.0066 17.4 3.9 0.33 11.9 1.1 2.3 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK43118.1 - 0.0076 16.7 10.8 0.046 14.2 2.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain MTHFR_C PF12225.8 KKK43118.1 - 0.026 14.2 3.9 0.42 10.3 0.3 2.3 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal Fer4_6 PF12837.7 KKK43118.1 - 0.063 13.4 2.7 0.063 13.4 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain B12-binding PF02310.19 KKK43120.1 - 1.4e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain TetR_C_8 PF14278.6 KKK43120.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 1 0 1 1 1 0 Transcriptional regulator C-terminal region Peptidase_M48 PF01435.18 KKK43121.1 - 4.8e-30 104.8 0.0 1e-29 103.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KKK43121.1 - 0.00085 18.6 0.1 0.00085 18.6 0.1 2.3 3 0 0 3 3 3 1 BlaR1 peptidase M56 DUF3262 PF11660.8 KKK43121.1 - 0.07 13.5 0.2 0.07 13.5 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3262) PAS_9 PF13426.7 KKK43125.1 - 2.5e-54 181.9 10.0 5.1e-17 62.0 0.0 6.3 7 0 0 7 7 7 4 PAS domain PAS PF00989.25 KKK43125.1 - 2.8e-51 172.3 0.1 3.3e-16 59.3 0.0 5.7 6 0 0 6 6 5 4 PAS fold PAS_3 PF08447.12 KKK43125.1 - 3.5e-39 133.0 0.0 1.4e-11 44.6 0.0 4.6 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 KKK43125.1 - 2.6e-36 124.2 0.0 2.1e-14 53.7 0.0 5.9 6 1 0 6 6 6 4 PAS fold Response_reg PF00072.24 KKK43125.1 - 3.3e-26 91.6 0.8 3.1e-25 88.5 0.2 2.7 2 0 0 2 2 2 1 Response regulator receiver domain PAS_8 PF13188.7 KKK43125.1 - 1.6e-22 79.0 0.0 1.5e-07 31.3 0.0 5.2 5 0 0 5 5 5 3 PAS domain HATPase_c PF02518.26 KKK43125.1 - 3.3e-16 59.8 0.2 1.5e-15 57.7 0.2 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 KKK43125.1 - 7.3e-12 45.8 0.0 1.7e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 GAF domain PAS_11 PF14598.6 KKK43125.1 - 4.5e-09 36.4 0.1 0.0085 16.2 0.0 4.2 4 0 0 4 4 4 2 PAS domain HisKA PF00512.25 KKK43125.1 - 5.3e-08 32.8 1.6 1.6e-07 31.3 0.1 2.7 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain MEKHLA PF08670.11 KKK43125.1 - 6.3e-08 32.6 0.0 0.28 11.1 0.0 4.7 4 0 0 4 4 4 2 MEKHLA domain GAF_3 PF13492.6 KKK43125.1 - 4.7e-06 27.0 0.0 0.00018 21.9 0.0 2.7 3 0 0 3 3 2 1 GAF domain PAS_10 PF13596.6 KKK43125.1 - 1.7e-05 25.3 8.0 0.00032 21.2 0.1 5.4 6 0 0 6 6 5 1 PAS domain GAF PF01590.26 KKK43125.1 - 0.00039 21.1 0.0 0.0032 18.1 0.0 2.4 2 0 0 2 2 2 1 GAF domain FleQ PF06490.11 KKK43125.1 - 0.0075 16.6 0.0 0.022 15.2 0.0 1.9 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Arylsulfotran_N PF17425.2 KKK43125.1 - 0.067 13.2 0.0 0.35 10.9 0.0 2.2 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain DUF3888 PF13027.6 KKK43125.1 - 0.1 13.1 2.2 2 8.9 0.2 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) Paz_1 PF18349.1 KKK43126.1 - 0.065 13.2 0.1 0.075 13.0 0.1 1.1 1 0 0 1 1 1 0 PAZ domain PAS_4 PF08448.10 KKK43127.1 - 0.0033 17.7 0.0 0.0039 17.4 0.0 1.1 1 0 0 1 1 1 1 PAS fold CheD PF03975.13 KKK43128.1 - 1.1e-19 70.6 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Jag_N PF14804.6 KKK43130.1 - 0.035 14.4 0.0 0.043 14.2 0.0 1.1 1 0 0 1 1 1 0 Jag N-terminus GAF_2 PF13185.6 KKK43131.1 - 1.2e-23 83.9 0.0 6.4e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 GAF domain PAS_9 PF13426.7 KKK43131.1 - 3e-19 69.2 1.1 1.2e-14 54.4 0.1 3.5 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KKK43131.1 - 6.1e-18 64.9 0.1 1.5e-14 54.0 0.0 3.1 3 0 0 3 3 2 2 PAS fold HATPase_c PF02518.26 KKK43131.1 - 5.1e-15 56.0 1.0 1.5e-14 54.4 0.4 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 KKK43131.1 - 9.8e-14 52.1 0.0 3.2e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 GAF domain PAS_4 PF08448.10 KKK43131.1 - 1.4e-12 47.8 0.0 3.4e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KKK43131.1 - 2.3e-11 43.8 0.0 2e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold GAF_3 PF13492.6 KKK43131.1 - 1.4e-06 28.6 0.0 0.00083 19.7 0.0 2.6 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 KKK43131.1 - 9.2e-06 25.6 0.0 3.9e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 KKK43131.1 - 9.7e-05 22.5 0.3 0.12 12.5 0.0 3.7 3 1 0 3 3 3 1 PAS fold SpoVT_C PF15714.5 KKK43131.1 - 0.0075 16.3 0.5 0.26 11.3 0.0 3.2 3 0 0 3 3 3 1 Stage V sporulation protein T C-terminal, transcription factor HATPase_c_5 PF14501.6 KKK43131.1 - 0.011 15.6 0.5 0.057 13.3 0.5 2.3 1 0 0 1 1 1 0 GHKL domain HisKA PF00512.25 KKK43131.1 - 0.1 12.6 1.8 0.38 10.8 0.9 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain SLATT_6 PF18169.1 KKK43131.1 - 0.12 12.0 3.5 0.24 11.0 0.5 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 HATPase_c PF02518.26 KKK43132.1 - 1.6e-17 64.0 0.3 2.1e-17 63.6 0.3 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK43132.1 - 2e-06 27.7 3.3 2e-06 27.7 3.3 1.8 1 1 1 2 2 2 1 GHKL domain HATPase_c_2 PF13581.6 KKK43132.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain EB_dh PF09459.10 KKK43134.1 - 1.5e-20 74.2 1.4 2.1e-20 73.8 1.4 1.2 1 0 0 1 1 1 1 Ethylbenzene dehydrogenase GYD PF08734.11 KKK43134.1 - 0.089 12.8 0.2 11 6.1 0.0 2.5 2 0 0 2 2 2 0 GYD domain EB_dh PF09459.10 KKK43137.1 - 1.6e-12 47.9 3.7 6.2e-12 46.0 3.7 1.8 1 1 0 1 1 1 1 Ethylbenzene dehydrogenase Phage_integrase PF00589.22 KKK43138.1 - 1.4e-39 135.6 0.1 2.4e-39 134.9 0.1 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KKK43138.1 - 3e-09 37.0 0.0 1.4e-08 34.9 0.0 2.1 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 KKK43138.1 - 0.0002 21.8 0.1 0.0016 18.8 0.0 2.5 2 1 1 3 3 3 1 Phage integrase, N-terminal SAM-like domain AAA_22 PF13401.6 KKK43139.1 - 1.5e-09 38.3 0.0 3.9e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK43139.1 - 1.8e-07 31.7 0.0 8.2e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 KKK43139.1 - 2.3e-07 30.4 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Cdc6_C PF09079.11 KKK43139.1 - 2.4e-06 27.4 0.1 5.6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain NACHT PF05729.12 KKK43139.1 - 5.1e-06 26.5 0.1 1.5e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 KKK43139.1 - 4.4e-05 23.9 0.1 0.00011 22.6 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKK43139.1 - 0.0013 18.0 0.0 0.0025 17.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 KKK43139.1 - 0.0029 17.6 0.5 0.015 15.3 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKK43139.1 - 0.0089 15.8 0.1 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KKK43139.1 - 0.011 15.0 0.1 0.7 9.1 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain RuvB_N PF05496.12 KKK43139.1 - 0.021 14.5 0.1 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RFX_DNA_binding PF02257.15 KKK43139.1 - 0.028 15.0 0.1 0.078 13.6 0.1 1.7 1 0 0 1 1 1 0 RFX DNA-binding domain Daxx PF03344.15 KKK43139.1 - 0.06 13.4 0.3 0.29 11.2 0.0 2.1 3 0 0 3 3 3 0 Daxx N-terminal Rassf1C-interacting domain IstB_IS21 PF01695.17 KKK43139.1 - 0.061 13.0 0.0 0.57 9.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AIG1 PF04548.16 KKK43139.1 - 0.087 12.1 1.0 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 AIG1 family Zn-ribbon_8 PF09723.10 KKK43140.1 - 0.00036 20.6 0.8 0.0006 19.9 0.8 1.3 1 0 0 1 1 1 1 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK43140.1 - 0.0079 16.1 0.8 0.015 15.2 0.8 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-RING_7 PF02591.15 KKK43140.1 - 0.036 14.3 1.1 6.4 7.0 0.5 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain Zn_ribbon_recom PF13408.6 KKK43140.1 - 0.047 14.2 4.8 0.079 13.5 0.7 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.6 KKK43140.1 - 0.051 13.0 1.7 2.2 7.8 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KKK43140.1 - 0.051 13.5 0.5 0.094 12.7 0.5 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF2318 PF10080.9 KKK43140.1 - 0.057 13.6 0.2 0.065 13.4 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-ISL3 PF14690.6 KKK43140.1 - 0.061 14.0 3.2 7.2 7.4 0.2 2.6 1 1 2 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Prim_Zn_Ribbon PF08273.12 KKK43140.1 - 0.071 13.4 2.7 0.14 12.4 2.7 1.6 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase SIR2 PF02146.17 KKK43140.1 - 0.11 12.5 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Sir2 family zf-C2H2_3 PF13878.6 KKK43140.1 - 0.17 11.8 1.3 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Rubredoxin_2 PF18073.1 KKK43140.1 - 0.18 11.5 3.6 7.6 6.4 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain TF_Zn_Ribbon PF08271.12 KKK43140.1 - 0.46 10.0 5.0 4.9 6.8 5.0 2.3 1 1 0 1 1 1 0 TFIIB zinc-binding DUF362 PF04015.12 KKK43141.1 - 8.2e-22 78.4 0.0 1.1e-21 78.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF362) Fer4_9 PF13187.6 KKK43141.1 - 0.06 13.5 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_11 PF13247.6 KKK43141.1 - 0.076 13.2 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain RMMBL PF07521.12 KKK43143.1 - 9.7e-06 25.4 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Flavin_Reduct PF01613.18 KKK43144.1 - 4.4e-19 69.1 0.0 5.1e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain fn3_PAP PF17808.1 KKK43144.1 - 0.084 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Cdc6_C PF09079.11 KKK43148.1 - 2.4e-14 53.1 0.0 6e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_22 PF13401.6 KKK43148.1 - 4.6e-11 43.1 0.0 9.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK43148.1 - 1.4e-05 25.6 0.1 4.5e-05 23.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KKK43148.1 - 1.4e-05 25.5 0.1 9.9e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 KKK43148.1 - 0.0019 18.0 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_7 PF12775.7 KKK43148.1 - 0.0025 17.4 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KKK43148.1 - 0.0037 17.6 0.0 0.0097 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase PolyA_pol_RNAbd PF12627.7 KKK43148.1 - 0.025 14.3 0.1 3.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A Kinesin PF00225.23 KKK43148.1 - 0.031 13.2 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain NACHT PF05729.12 KKK43148.1 - 0.037 14.0 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain GTF2I PF02946.14 KKK43148.1 - 0.041 14.0 0.0 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 GTF2I-like repeat AAA_lid_10 PF17872.1 KKK43148.1 - 0.071 13.2 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 KKK43148.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_assoc_2 PF16193.5 KKK43148.1 - 0.094 13.1 1.8 0.28 11.5 0.1 2.4 2 0 0 2 2 2 0 AAA C-terminal domain DUF1664 PF07889.12 KKK43152.1 - 0.00011 22.2 22.0 0.0016 18.5 6.6 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) ATG16 PF08614.11 KKK43152.1 - 0.00023 21.4 34.1 0.14 12.3 21.7 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 KKK43152.1 - 0.00033 20.7 15.3 0.011 15.8 5.1 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 KKK43152.1 - 0.0015 17.9 11.4 0.0015 17.9 11.4 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) APG6_N PF17675.1 KKK43152.1 - 0.0016 19.0 44.9 0.042 14.4 4.9 3.0 1 1 2 3 3 3 2 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KKK43152.1 - 0.0019 18.3 41.0 0.054 13.5 18.6 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KKK43152.1 - 0.0032 17.1 37.1 0.2 11.2 20.7 2.9 1 1 1 2 2 2 2 Intermediate filament protein DUF3584 PF12128.8 KKK43152.1 - 0.0033 15.0 27.3 0.0041 14.7 27.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 KKK43152.1 - 0.0047 16.8 15.5 0.0047 16.8 15.5 2.6 1 1 2 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) Prefoldin_2 PF01920.20 KKK43152.1 - 0.011 15.6 2.8 0.011 15.6 2.8 4.5 1 1 3 4 4 4 0 Prefoldin subunit MAD PF05557.13 KKK43152.1 - 0.016 13.6 36.9 0.026 12.9 36.9 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein GIT_CC PF16559.5 KKK43152.1 - 0.021 14.7 1.6 0.021 14.7 1.6 3.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 KKK43152.1 - 0.026 13.4 41.3 0.19 10.6 31.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KKK43152.1 - 0.033 14.2 42.0 0.64 10.1 12.3 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 KKK43152.1 - 0.033 14.3 43.9 0.8 9.9 6.7 3.0 1 1 1 2 2 2 0 Tropomyosin like ApoO PF09769.9 KKK43152.1 - 0.035 14.1 9.0 0.11 12.4 0.5 3.4 1 1 2 3 3 3 0 Apolipoprotein O zf-C4H2 PF10146.9 KKK43152.1 - 0.04 14.2 36.6 0.45 10.8 15.7 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein Golgin_A5 PF09787.9 KKK43152.1 - 0.059 12.8 35.1 3.4 7.1 18.6 2.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 IFT57 PF10498.9 KKK43152.1 - 0.077 12.0 35.4 0.36 9.8 25.8 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Lectin_N PF03954.14 KKK43152.1 - 0.077 12.7 13.9 0.35 10.6 5.3 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain HAUS-augmin3 PF14932.6 KKK43152.1 - 0.12 12.0 32.2 0.26 10.9 4.9 2.5 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 KKK43152.1 - 0.12 11.7 28.6 0.41 9.9 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Flagellin_C PF00700.21 KKK43152.1 - 0.13 12.6 13.0 0.49 10.8 0.5 3.7 1 1 3 4 4 3 0 Bacterial flagellin C-terminal helical region DUF724 PF05266.14 KKK43152.1 - 0.15 11.9 33.6 0.019 14.8 12.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Tektin PF03148.14 KKK43152.1 - 0.15 10.8 39.1 0.054 12.3 4.5 3.1 1 1 0 2 2 2 0 Tektin family DHR10 PF18595.1 KKK43152.1 - 0.16 12.0 45.3 0.22 11.6 8.1 4.0 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain WXG100 PF06013.12 KKK43152.1 - 0.17 12.2 8.3 5.7 7.2 0.0 3.9 1 1 2 4 4 4 0 Proteins of 100 residues with WXG AAA_13 PF13166.6 KKK43152.1 - 0.25 10.0 36.2 0.78 8.3 36.2 1.9 1 1 0 1 1 1 0 AAA domain HAUS2 PF15003.6 KKK43152.1 - 0.4 10.4 15.7 0.088 12.5 7.6 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 HemX PF04375.14 KKK43152.1 - 0.5 9.6 25.4 0.13 11.6 3.9 2.6 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Atg14 PF10186.9 KKK43152.1 - 0.57 9.2 41.1 6.5 5.7 30.8 2.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 KKK43152.1 - 0.59 9.5 46.6 0.45 9.8 30.8 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LXG PF04740.12 KKK43152.1 - 0.63 9.7 24.2 0.27 10.9 18.2 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF4201 PF13870.6 KKK43152.1 - 0.67 9.7 47.2 0.075 12.8 8.4 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4201) hNIFK_binding PF12196.8 KKK43152.1 - 0.73 9.4 3.9 0.3 10.6 0.5 2.1 2 0 0 2 2 1 0 FHA Ki67 binding domain of hNIFK Exonuc_VII_L PF02601.15 KKK43152.1 - 0.8 9.2 30.1 0.58 9.7 22.6 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit COG2 PF06148.11 KKK43152.1 - 0.98 9.5 22.1 0.23 11.5 3.0 3.8 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.8 KKK43152.1 - 1.1 9.3 43.5 0.099 12.7 12.7 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FPP PF05911.11 KKK43152.1 - 1.3 7.1 35.0 5.2 5.1 34.9 1.7 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil KfrA_N PF11740.8 KKK43152.1 - 1.9 9.2 13.5 3 8.5 0.2 3.4 2 1 1 3 3 2 0 Plasmid replication region DNA-binding N-term Ndc1_Nup PF09531.10 KKK43152.1 - 2.5 6.7 8.7 3.5 6.2 8.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5082 PF16888.5 KKK43152.1 - 2.7 8.3 33.9 1.8e+04 -4.9 33.7 3.7 1 1 0 1 1 0 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 KKK43152.1 - 2.8 8.3 32.8 0.18 12.1 1.2 4.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 KKK43152.1 - 2.8 8.3 40.7 34 4.8 17.3 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 KKK43152.1 - 3.1 5.6 24.8 0.61 8.0 9.8 2.0 1 1 0 1 1 1 0 Prominin Jnk-SapK_ap_N PF09744.9 KKK43152.1 - 3.2 8.0 38.5 3 8.0 17.3 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CALCOCO1 PF07888.11 KKK43152.1 - 3.2 6.5 39.5 3.4 6.4 32.2 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4618 PF15397.6 KKK43152.1 - 3.3 7.1 34.2 0.18 11.2 1.9 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4618) DUF3086 PF11285.8 KKK43152.1 - 4.8 6.2 21.4 12 4.9 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) DUF2968 PF11180.8 KKK43152.1 - 5.5 6.6 20.7 0.36 10.5 7.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) TMF_TATA_bd PF12325.8 KKK43152.1 - 5.5 7.3 34.4 0.27 11.5 2.7 3.8 1 1 3 4 4 3 0 TATA element modulatory factor 1 TATA binding Mod_r PF07200.13 KKK43152.1 - 5.6 7.1 34.6 44 4.2 15.3 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_CLD_2 PF14197.6 KKK43152.1 - 5.7 7.1 44.1 1.3 9.2 9.3 4.5 1 1 2 4 4 4 0 Centrosome localisation domain of PPC89 RmuC PF02646.16 KKK43152.1 - 6.5 5.8 28.3 0.64 9.1 4.1 3.1 2 1 1 3 3 3 0 RmuC family DUF4600 PF15372.6 KKK43152.1 - 6.7 7.2 35.5 2.6e+02 2.0 20.3 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Seryl_tRNA_N PF02403.22 KKK43152.1 - 6.7 7.0 46.2 0.93 9.8 19.3 3.8 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain HMMR_N PF15905.5 KKK43152.1 - 6.9 6.0 43.8 3.8 6.9 6.9 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 KKK43152.1 - 7.2 6.8 30.8 8.9 6.5 17.3 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 KKK43152.1 - 8.2 6.8 37.6 4.7 7.6 4.9 2.1 1 1 1 2 2 2 0 Fez1 Phage_GP20 PF06810.11 KKK43152.1 - 8.6 6.1 39.7 0.41 10.4 10.2 3.2 1 1 1 2 2 1 0 Phage minor structural protein GP20 DUF4200 PF13863.6 KKK43152.1 - 9.8 6.6 48.1 0.3 11.5 21.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) MerR-DNA-bind PF09278.11 KKK43152.1 - 9.9 6.8 11.4 15 6.2 1.0 3.5 2 2 1 3 3 2 0 MerR, DNA binding TMPIT PF07851.13 KKK43152.1 - 10 5.3 28.7 3.9 6.6 15.8 2.3 1 1 1 2 2 2 0 TMPIT-like protein ubiquitin PF00240.23 KKK43153.1 - 7.5e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family ubiquitin PF00240.23 KKK43154.1 - 0.0014 18.4 0.1 0.0031 17.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2614 PF11023.8 KKK43154.1 - 0.0096 16.0 2.3 0.018 15.1 2.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon containing domain Ubiquitin_4 PF18036.1 KKK43154.1 - 0.06 13.4 0.1 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain HrcA_DNA-bdg PF03444.15 KKK43155.1 - 1.9e-05 24.2 2.1 1.9e-05 24.2 2.1 2.4 3 0 0 3 3 3 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_5 PF01022.20 KKK43155.1 - 0.00024 20.9 0.0 0.37 10.7 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 KKK43155.1 - 0.00038 20.3 2.9 0.041 13.8 2.7 2.9 3 0 0 3 3 3 1 HTH domain Dimerisation2 PF16864.5 KKK43155.1 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Phage_rep_org_N PF09681.10 KKK43155.1 - 0.028 14.3 6.4 0.045 13.7 0.9 2.7 1 1 2 3 3 3 0 N-terminal phage replisome organiser (Phage_rep_org_N) TrmB PF01978.19 KKK43155.1 - 0.03 14.2 0.8 0.73 9.8 0.2 2.9 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 KKK43155.1 - 0.039 14.3 4.0 0.081 13.3 1.3 2.7 2 1 1 3 3 3 0 Penicillinase repressor FaeA PF04703.12 KKK43155.1 - 0.063 13.7 3.7 4.8 7.6 0.0 3.2 3 1 0 3 3 3 0 FaeA-like protein HTH_20 PF12840.7 KKK43155.1 - 0.074 13.1 0.0 4.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Rrf2 PF02082.20 KKK43155.1 - 0.12 12.8 2.1 0.44 10.9 0.4 2.4 3 0 0 3 3 2 0 Transcriptional regulator Phage_rep_O PF04492.13 KKK43155.1 - 0.13 12.9 6.5 2.5 8.8 2.0 2.4 2 0 0 2 2 2 0 Bacteriophage replication protein O HTH_36 PF13730.6 KKK43155.1 - 1.1 9.2 6.4 0.33 10.9 0.9 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain NUMOD1 PF07453.13 KKK43155.1 - 1.3 9.4 11.5 0.18 12.1 0.9 3.9 4 0 0 4 4 4 0 NUMOD1 domain DUF5100 PF17029.5 KKK43155.1 - 2 8.3 11.1 0.35 10.7 5.9 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5100) HTH_45 PF14947.6 KKK43155.1 - 5.3 7.1 14.1 0.99 9.4 7.4 2.7 2 1 1 3 3 3 0 Winged helix-turn-helix ubiquitin PF00240.23 KKK43156.1 - 6.1e-07 29.1 0.0 9.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KKK43156.1 - 0.00023 20.9 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ThiF PF00899.21 KKK43157.1 - 1.9e-54 184.6 0.0 2.6e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family UQ_con PF00179.26 KKK43158.1 - 2.1e-24 85.8 0.1 2.7e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK43158.1 - 0.0053 17.0 0.1 0.0082 16.4 0.1 1.4 1 0 0 1 1 1 1 RWD domain JAB PF01398.21 KKK43159.1 - 2e-16 60.0 0.0 3.1e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 KKK43159.1 - 1.1e-05 25.5 5.5 1.2e-05 25.5 0.3 2.3 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0172) Prok-JAB PF14464.6 KKK43159.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF1068 PF06364.12 KKK43159.1 - 0.032 14.1 2.6 0.053 13.4 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) XPA_C PF05181.12 KKK43159.1 - 0.085 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 XPA protein C-terminus Zn_ribbon_17 PF17120.5 KKK43160.1 - 0.28 10.8 0.6 0.51 10.0 0.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CCDC106 PF15794.5 KKK43160.1 - 0.59 9.8 9.2 0.85 9.3 9.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TFIIF_alpha PF05793.12 KKK43160.1 - 3.6 6.1 9.1 4.9 5.6 9.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GCHY-1 PF02649.14 KKK43161.1 - 1.2e-59 202.0 0.4 1.3e-59 201.8 0.4 1.0 1 0 0 1 1 1 1 Type I GTP cyclohydrolase folE2 CBS PF00571.28 KKK43162.1 - 1e-18 67.5 1.1 4.7e-09 36.5 0.2 2.8 2 1 0 2 2 2 2 CBS domain ELFV_dehydrog PF00208.21 KKK43162.1 - 8.3e-18 65.0 0.0 1.6e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Gp_dh_N PF00044.24 KKK43162.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain BcrAD_BadFG PF01869.20 KKK43165.1 - 2.4e-31 109.2 0.1 3e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 KKK43165.1 - 0.006 17.0 0.1 0.15 12.5 0.0 2.2 2 0 0 2 2 2 1 Cell division protein FtsA FGGY_N PF00370.21 KKK43165.1 - 0.0066 16.0 0.1 1.3 8.5 0.1 2.1 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain VIT1 PF01988.19 KKK43166.1 - 1.3e-07 31.7 0.1 1.4e-07 31.6 0.1 1.0 1 0 0 1 1 1 1 VIT family DUF3285 PF11688.8 KKK43166.1 - 9 6.3 7.3 0.51 10.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) VIT1 PF01988.19 KKK43167.1 - 6.2e-10 39.3 14.2 5.1e-05 23.2 9.2 2.1 1 1 1 2 2 2 2 VIT family Tmemb_170 PF10190.9 KKK43167.1 - 0.11 12.8 10.0 0.37 11.2 0.8 2.7 3 0 0 3 3 3 0 Putative transmembrane protein 170 Halogen_Hydrol PF10112.9 KKK43167.1 - 4.7 7.2 6.1 6.9 6.7 0.0 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Mer2 PF09074.10 KKK43170.1 - 0.01 15.6 0.3 0.14 12.0 0.0 2.1 1 1 1 2 2 2 0 Mer2 HTH_37 PF13744.6 KKK43170.1 - 0.016 15.2 0.8 0.029 14.3 0.2 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain AAA_3 PF07726.11 KKK43171.1 - 2.6e-65 218.2 0.2 4e-65 217.6 0.2 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK43171.1 - 4.6e-16 59.1 0.0 6.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KKK43171.1 - 2.2e-07 31.4 0.1 4.2e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KKK43171.1 - 8.5e-07 28.8 0.1 7e-06 25.9 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KKK43171.1 - 6.4e-06 26.0 0.1 2.1e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 KKK43171.1 - 1.4e-05 24.3 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 KKK43171.1 - 0.00068 19.1 0.3 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KKK43171.1 - 0.012 16.1 0.1 0.12 12.7 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 KKK43171.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KKK43171.1 - 0.02 15.1 0.1 0.042 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KKK43171.1 - 0.031 14.4 0.0 0.089 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KKK43171.1 - 0.049 13.5 0.1 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 KKK43171.1 - 0.064 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KKK43171.1 - 0.084 13.2 0.0 3.7 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KKK43171.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain PI-TkoII_IV PF18714.1 KKK43174.1 - 0.039 13.4 0.1 0.53 9.8 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase II intein Domain IV Lsm_C PF14894.6 KKK43175.1 - 1.7e-10 40.5 2.3 2.9e-10 39.8 0.3 2.3 2 2 1 3 3 3 1 Lsm C-terminal LSM PF01423.22 KKK43175.1 - 2.9e-05 23.6 0.2 5.1e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KKK43175.1 - 0.054 13.6 0.6 0.082 13.0 0.5 1.5 1 1 0 1 1 1 0 Scd6-like Sm domain cobW PF02492.19 KKK43176.1 - 1.3e-24 86.8 1.1 1.8e-24 86.3 1.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KKK43176.1 - 5.2e-05 22.9 5.2 0.0006 19.4 5.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KKK43176.1 - 9.4e-05 21.5 2.8 0.0022 17.0 2.8 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KKK43176.1 - 0.0003 20.7 1.5 0.42 10.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 KKK43176.1 - 0.00056 19.2 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PduV-EutP PF10662.9 KKK43176.1 - 0.0028 17.4 0.8 0.28 10.9 0.3 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KKK43176.1 - 0.0037 16.9 0.1 0.044 13.4 0.0 2.2 2 0 0 2 2 2 1 Ras family Arf PF00025.21 KKK43176.1 - 0.0046 16.4 1.2 0.075 12.5 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 KKK43176.1 - 0.011 16.1 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KKK43176.1 - 0.018 15.5 0.1 0.054 13.9 0.0 1.9 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KKK43176.1 - 0.018 14.1 0.9 0.035 13.1 0.2 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 KKK43176.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 KKK43176.1 - 0.03 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3540 PF12059.8 KKK43176.1 - 0.061 13.2 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) ATP-synt_ab PF00006.25 KKK43176.1 - 0.15 11.6 0.1 0.24 11.0 0.1 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain zf-AN1 PF01428.16 KKK43177.1 - 3.7e-12 46.2 7.6 5.5e-12 45.6 7.6 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Rhomboid PF01694.22 KKK43177.1 - 0.00038 20.5 13.9 0.00038 20.5 13.9 2.1 1 1 1 2 2 2 1 Rhomboid family LRRC37AB_C PF14914.6 KKK43177.1 - 0.017 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain SNARE PF05739.19 KKK43177.1 - 0.062 13.3 0.0 0.062 13.3 0.0 3.1 4 0 0 4 4 4 0 SNARE domain zf-C2H2_4 PF13894.6 KKK43177.1 - 2.4 9.2 8.3 0.46 11.5 2.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-AN1 PF01428.16 KKK43178.1 - 3.2e-05 24.0 9.2 6.8e-05 23.0 9.2 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Peptidase_M50 PF02163.22 KKK43178.1 - 8.4e-05 22.0 12.8 0.00045 19.6 1.0 3.2 1 1 1 2 2 2 2 Peptidase family M50 DZR PF12773.7 KKK43178.1 - 0.011 15.7 4.0 0.018 15.0 4.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK43178.1 - 0.068 12.9 4.2 0.13 12.0 4.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK43178.1 - 0.081 12.4 2.2 0.16 11.4 2.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Stomagen PF16851.5 KKK43178.1 - 0.11 12.6 0.5 1.3 9.1 0.3 2.2 2 0 0 2 2 2 0 Stomagen DUF2630 PF10944.8 KKK43179.1 - 0.018 15.5 1.1 0.022 15.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Ogr_Delta PF04606.12 KKK43180.1 - 0.012 15.6 2.5 1.2 9.1 0.3 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.6 KKK43180.1 - 0.019 14.3 0.2 0.019 14.3 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbon domain IBR PF01485.21 KKK43180.1 - 0.028 14.6 4.1 0.046 13.9 4.1 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain NADH-G_4Fe-4S_3 PF10588.9 KKK43180.1 - 0.035 13.6 0.2 0.069 12.7 0.2 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Zn-ribbon_8 PF09723.10 KKK43180.1 - 0.035 14.2 0.8 0.065 13.4 0.8 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-TFIIB PF13453.6 KKK43180.1 - 0.15 11.4 0.7 0.15 11.4 0.7 2.7 3 0 0 3 3 3 0 Transcription factor zinc-finger Cys_rich_KTR PF14205.6 KKK43180.1 - 3 7.7 9.6 11 6.0 6.2 2.2 1 1 1 2 2 2 0 Cysteine-rich KTR zf-C4_Topoisom PF01396.19 KKK43180.1 - 3.2 7.6 8.3 0.21 11.4 1.1 2.3 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger AdoMet_Synthase PF01941.19 KKK43181.1 - 4e-26 91.7 0.1 4.2e-26 91.6 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) AdoMet_Synthase PF01941.19 KKK43182.1 - 6.8e-148 492.7 0.1 7.4e-148 492.5 0.1 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase (AdoMet synthetase) Nup35_RRM_2 PF14605.6 KKK43182.1 - 0.056 13.5 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif S-AdoMet_synt_N PF00438.20 KKK43182.1 - 0.058 14.1 3.2 0.18 12.5 0.1 2.7 2 1 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain MCH PF02289.16 KKK43182.1 - 0.072 12.4 0.2 0.77 9.0 0.0 2.0 1 1 1 2 2 2 0 Cyclohydrolase (MCH) HTH_3 PF01381.22 KKK43183.1 - 0.00015 21.7 0.6 0.00045 20.2 0.6 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 KKK43183.1 - 0.0074 16.3 1.2 0.0074 16.3 1.2 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 KKK43183.1 - 0.064 13.2 0.5 3.4 7.7 0.0 2.9 2 0 0 2 2 2 0 HTH domain Phage_CI_repr PF07022.13 KKK43183.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain RNase_HII PF01351.18 KKK43184.1 - 1.9e-50 171.5 0.2 2.2e-50 171.3 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease HII LPD18 PF18832.1 KKK43185.1 - 0.089 12.9 0.1 0.089 12.9 0.1 1.0 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 MTS PF05175.14 KKK43188.1 - 5.7e-15 55.3 0.0 6.3e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KKK43188.1 - 0.0017 18.0 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KKK43188.1 - 0.061 12.9 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KKK43188.1 - 0.073 12.5 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KKK43188.1 - 0.073 12.9 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 KKK43188.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RNA_pol_Rpb5_C PF01191.19 KKK43189.1 - 1.9e-24 85.3 0.2 2.1e-24 85.2 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb2_6 PF00562.28 KKK43190.1 - 4.4e-122 407.9 0.0 6.5e-122 407.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKK43190.1 - 1.9e-55 187.5 0.1 2.9e-55 186.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KKK43190.1 - 2.5e-35 121.8 0.3 5.2e-35 120.8 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KKK43190.1 - 2e-29 101.8 0.1 4.2e-29 100.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KKK43190.1 - 8.9e-25 86.7 0.0 1.9e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KKK43190.1 - 2.8e-22 78.7 0.5 6.2e-22 77.7 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KKK43190.1 - 6.5e-13 49.0 2.8 2.5e-12 47.2 2.8 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NOB1_Zn_bind PF08772.11 KKK43190.1 - 0.0058 16.8 0.2 0.013 15.6 0.2 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like RNA_pol_Rpb2_45 PF10385.9 KKK43190.1 - 0.025 14.8 0.2 0.14 12.4 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain zf-NADH-PPase PF09297.11 KKK43190.1 - 0.13 11.9 1.2 2.1 8.1 0.0 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.12 KKK43190.1 - 0.35 11.1 2.1 0.83 9.9 2.1 1.7 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CbtA PF09490.10 KKK43191.1 - 1.1 8.9 8.2 1.9 8.2 8.2 1.3 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Cation_ATPase_C PF00689.21 KKK43191.1 - 3.7 7.2 25.6 0.18 11.5 4.5 3.0 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus TssN PF17555.2 KKK43191.1 - 6.8 6.0 20.6 16 4.7 20.6 1.6 1 1 0 1 1 1 0 Type VI secretion system, TssN EMP70 PF02990.16 KKK43191.1 - 8.6 4.9 22.5 27 3.3 22.5 1.6 1 1 0 1 1 1 0 Endomembrane protein 70 Radical_SAM PF04055.21 KKK43195.1 - 2.1e-15 57.5 0.1 3.1e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK43195.1 - 0.0096 16.2 0.5 0.017 15.4 0.1 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK43195.1 - 0.97 9.6 3.9 1.6 8.9 1.5 2.5 3 1 0 3 3 3 0 4Fe-4S single cluster domain NosD PF05048.13 KKK43196.1 - 4.7e-110 366.5 323.2 5.6e-20 71.6 41.2 11.0 4 4 6 11 11 11 11 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK43196.1 - 6.5e-104 344.5 442.4 1.5e-20 73.6 38.8 12.4 4 4 9 14 14 14 14 Right handed beta helix region Collagen PF01391.18 KKK43196.1 - 0.00042 20.0 31.1 0.00083 19.1 31.1 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) LapA_dom PF06305.11 KKK43196.1 - 0.14 12.0 1.2 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FERM_f0 PF16511.5 KKK43196.1 - 0.27 11.6 4.4 15 6.0 0.1 3.5 3 1 0 3 3 3 0 N-terminal or F0 domain of Talin-head FERM Pectate_lyase_3 PF12708.7 KKK43196.1 - 0.6 9.9 177.0 0.014 15.3 15.5 10.7 5 3 4 10 10 10 0 Pectate lyase superfamily protein CoA_trans PF01144.23 KKK43197.1 - 5.5e-24 84.8 0.4 6.4e-24 84.6 0.4 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CCG PF02754.16 KKK43199.1 - 8.2e-06 26.0 0.2 1.1e-05 25.6 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich domain Cas_TM1802 PF09484.10 KKK43199.1 - 0.013 14.3 0.3 0.016 14.0 0.3 1.2 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) AID PF18767.1 KKK43199.1 - 0.031 14.3 0.4 2.9 8.0 0.0 2.8 2 1 1 3 3 3 0 Activation induced deaminase Fer4 PF00037.27 KKK43200.1 - 3.9e-13 48.6 14.9 3.6e-07 29.7 4.6 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK43200.1 - 6.4e-09 36.3 11.2 6.4e-09 36.3 11.2 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43200.1 - 6.5e-07 29.2 13.6 2.8e-05 24.0 3.9 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK43200.1 - 1.1e-06 28.7 10.8 1.1e-06 28.7 10.8 2.6 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43200.1 - 1.4e-06 28.4 34.3 3.8e-06 27.0 14.1 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43200.1 - 3e-06 27.0 10.7 0.00021 21.2 1.5 3.2 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK43200.1 - 8.7e-05 22.6 20.5 0.018 15.2 0.2 3.0 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK43200.1 - 0.0003 21.1 15.6 0.004 17.6 3.8 3.4 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK43200.1 - 0.00062 20.7 20.2 0.0017 19.2 4.5 3.6 2 1 1 3 3 3 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK43200.1 - 0.00091 19.6 16.2 0.096 13.1 0.3 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK43200.1 - 0.0045 17.7 4.8 0.1 13.3 0.2 2.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_18 PF13746.6 KKK43200.1 - 0.0071 16.5 7.1 0.0071 16.5 7.1 1.9 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK43200.1 - 0.025 15.1 11.4 0.17 12.5 2.3 3.3 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I DUF4258 PF14076.6 KKK43200.1 - 0.14 12.5 1.1 0.34 11.3 0.1 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4258) IF2_N PF04760.15 KKK43200.1 - 0.18 11.7 0.1 0.38 10.6 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Fer4_17 PF13534.6 KKK43200.1 - 0.51 10.9 27.8 2 9.0 3.0 3.3 1 1 3 4 4 3 0 4Fe-4S dicluster domain PIN PF01850.21 KKK43201.1 - 1.7e-11 44.6 0.2 2.2e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 KKK43201.1 - 0.05 14.4 0.0 0.067 14.0 0.0 1.2 1 0 0 1 1 1 0 PIN domain DUF3333 PF11812.8 KKK43202.1 - 0.0075 16.5 0.1 0.0087 16.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3333) RHH_3 PF12651.7 KKK43202.1 - 0.022 14.7 0.3 0.63 10.0 0.3 2.4 1 1 0 1 1 1 0 Ribbon-helix-helix domain RHH_1 PF01402.21 KKK43202.1 - 0.062 13.3 4.3 0.15 12.0 0.8 2.8 2 1 0 2 2 2 0 Ribbon-helix-helix protein, copG family FA_FANCE PF11510.8 KKK43202.1 - 0.089 12.1 0.0 0.095 12.0 0.0 1.0 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE MM_CoA_mutase PF01642.22 KKK43203.1 - 2.3e-24 85.9 0.0 2.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase DUF4504 PF14953.6 KKK43203.1 - 0.22 10.9 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) KID PF02524.14 KKK43206.1 - 0.37 11.1 0.3 0.37 11.1 0.3 1.9 2 0 0 2 2 2 0 KID repeat PALP PF00291.25 KKK43208.1 - 1.4e-79 267.6 0.0 1.6e-79 267.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MULE PF10551.9 KKK43211.1 - 0.0096 16.3 0.1 0.022 15.2 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF5394 PF17372.2 KKK43211.1 - 0.14 11.7 2.4 0.29 10.7 2.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5394) DUF4207 PF13904.6 KKK43211.1 - 0.34 10.6 9.0 0.63 9.7 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) TMF_TATA_bd PF12325.8 KKK43212.1 - 0.002 18.3 6.3 0.0037 17.5 6.3 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Ly49 PF08391.10 KKK43212.1 - 0.014 15.7 5.9 0.034 14.5 5.9 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region 7TMR-HDED PF07697.11 KKK43212.1 - 0.028 14.5 1.8 0.027 14.6 1.8 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Atg14 PF10186.9 KKK43212.1 - 0.05 12.7 5.8 0.067 12.3 5.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_HK97_TLTM PF06120.11 KKK43212.1 - 0.37 9.9 6.3 0.51 9.5 6.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein YabA PF06156.13 KKK43212.1 - 0.67 10.6 9.6 0.53 11.0 6.5 2.2 2 1 0 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 KKK43212.1 - 0.77 10.1 9.2 0.86 9.9 3.4 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain RimK PF08443.11 KKK43213.1 - 8.5e-41 139.6 0.0 1.1e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 KKK43213.1 - 1.5e-12 47.2 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_ST PF14397.6 KKK43213.1 - 3.7e-11 42.8 0.1 8.3e-06 25.2 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 KKK43213.1 - 1.5e-09 38.1 0.0 2.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KKK43213.1 - 1.2e-05 24.9 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KKK43213.1 - 2.6e-05 23.6 0.0 0.083 12.1 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 KKK43213.1 - 0.00014 21.5 0.0 0.0016 18.0 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Rimk_N PF18030.1 KKK43213.1 - 0.004 17.5 0.0 0.0093 16.3 0.0 1.7 1 0 0 1 1 1 1 RimK PreATP-grasp domain GARS_A PF01071.19 KKK43213.1 - 0.0077 16.0 0.0 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 KKK43213.1 - 0.019 14.4 0.0 0.056 12.9 0.0 1.8 2 1 0 2 2 2 0 ATP-grasp domain PEMT PF04191.13 KKK43214.1 - 1.3e-08 35.1 1.3 1.3e-08 35.1 1.3 2.0 3 0 0 3 3 3 1 Phospholipid methyltransferase NnrU PF07298.11 KKK43214.1 - 3.2e-08 33.4 0.6 4.7e-08 32.8 0.6 1.2 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 KKK43214.1 - 3.4e-05 23.5 1.9 5.5e-05 22.8 1.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KKK43214.1 - 0.00013 22.3 0.7 0.00045 20.6 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family YMF19 PF02326.15 KKK43214.1 - 0.042 14.6 2.0 0.12 13.2 2.0 1.8 1 0 0 1 1 1 0 Plant ATP synthase F0 CD20 PF04103.15 KKK43215.1 - 0.19 11.8 10.3 0.99 9.5 7.0 2.0 2 0 0 2 2 2 0 CD20-like family YfhO PF09586.10 KKK43215.1 - 0.76 7.9 5.6 0.81 7.9 5.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4118 PF13493.6 KKK43215.1 - 2.7 7.8 15.5 22 4.9 5.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) DUF2981 PF11200.8 KKK43215.1 - 3.3 7.4 6.0 3.8 7.2 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF4282 PF14110.6 KKK43215.1 - 3.3 8.5 13.3 1.5 9.6 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF1003 PF06210.11 KKK43215.1 - 3.7 7.7 5.0 70 3.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) DUF983 PF06170.12 KKK43215.1 - 4.8 7.7 13.4 1.3 9.5 9.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF983) Maf PF02545.14 KKK43217.1 - 1.1e-43 149.0 0.0 1.2e-43 148.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF424 PF04242.13 KKK43217.1 - 0.07 13.4 0.9 0.3 11.4 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF424) RNA_pol_Rpb2_4 PF04566.13 KKK43217.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 CTP_transf_1 PF01148.20 KKK43219.1 - 6.4e-07 29.4 14.9 6.4e-07 29.4 14.9 2.4 1 1 1 2 2 2 1 Cytidylyltransferase family TMEM192 PF14802.6 KKK43219.1 - 0.0079 15.3 0.1 0.019 14.1 0.1 1.6 1 0 0 1 1 1 1 TMEM192 family DUF3021 PF11457.8 KKK43219.1 - 1.1 9.5 24.1 0.25 11.7 1.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) Keratin_assoc PF09775.9 KKK43219.1 - 2 8.1 9.1 0.16 11.6 2.3 2.6 3 0 0 3 3 3 0 Keratinocyte-associated protein 2 OST3_OST6 PF04756.13 KKK43219.1 - 7.7 5.8 12.6 3.7 6.8 1.7 2.8 2 1 1 3 3 3 0 OST3 / OST6 family, transporter family ThiS PF02597.20 KKK43220.1 - 3.8e-08 33.9 0.0 4.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family Urm1 PF09138.11 KKK43220.1 - 0.068 13.5 0.2 0.092 13.1 0.2 1.3 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) ThiS-like PF14453.6 KKK43220.1 - 0.14 12.2 1.1 0.9 9.6 0.1 2.5 2 1 0 2 2 2 0 ThiS-like ubiquitin Thymidylat_synt PF00303.19 KKK43221.1 - 7e-14 51.6 0.0 9.4e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase TatD_DNase PF01026.21 KKK43222.1 - 3.5e-48 164.2 0.0 3.9e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 KKK43222.1 - 0.0044 16.4 0.1 0.0078 15.6 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase family K-box PF01486.17 KKK43223.1 - 0.0018 18.4 1.9 0.0041 17.3 1.6 1.8 1 1 1 2 2 2 1 K-box region Phasin PF05597.11 KKK43223.1 - 0.029 14.4 0.5 1.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) bZIP_1 PF00170.21 KKK43223.1 - 0.029 14.5 0.3 0.071 13.2 0.1 1.8 2 1 0 2 2 2 0 bZIP transcription factor PEMT PF04191.13 KKK43224.1 - 4.4e-10 39.9 0.3 4.4e-10 39.9 0.3 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KKK43224.1 - 8.6e-08 32.5 0.4 1.7e-07 31.6 0.2 1.7 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KKK43224.1 - 4.3e-05 23.2 0.4 6.6e-05 22.5 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KKK43224.1 - 0.015 15.2 0.6 0.039 14.0 0.6 1.7 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase UPF0542 PF15086.6 KKK43224.1 - 0.041 13.8 0.2 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF2207 PF09972.9 KKK43224.1 - 3.1 6.5 10.4 2.3 6.9 0.1 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MCPsignal PF00015.21 KKK43225.1 - 8.8e-35 120.0 14.9 8.8e-35 120.0 14.9 2.7 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 KKK43225.1 - 0.00083 18.9 0.2 0.00083 18.9 0.2 4.8 4 1 0 4 4 3 1 Four helix bundle sensory module for signal transduction DUF4436 PF14494.6 KKK43225.1 - 0.0017 17.7 2.1 0.0041 16.4 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) T7SS_ESX_EspC PF10824.8 KKK43225.1 - 0.032 14.7 8.2 0.28 11.7 0.6 3.5 3 1 0 3 3 2 0 Excreted virulence factor EspC, type VII ESX diderm Laminin_II PF06009.12 KKK43225.1 - 0.033 14.2 17.0 1 9.4 6.5 3.5 3 1 0 3 3 3 0 Laminin Domain II DUF4446 PF14584.6 KKK43225.1 - 0.057 13.4 11.1 0.33 10.9 1.9 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF4446) DuoxA PF10204.9 KKK43225.1 - 0.1 11.6 2.0 0.19 10.7 2.0 1.4 1 0 0 1 1 1 0 Dual oxidase maturation factor Arfaptin PF06456.13 KKK43225.1 - 0.25 10.9 3.1 0.5 9.9 0.5 2.4 2 0 0 2 2 2 0 Arfaptin-like domain DUF1664 PF07889.12 KKK43225.1 - 0.32 11.0 12.7 0.66 10.0 3.8 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) MitMem_reg PF13012.6 KKK43225.1 - 0.34 11.3 4.3 1.3 9.5 1.5 2.7 2 2 0 2 2 2 0 Maintenance of mitochondrial structure and function Na_Ca_ex_C PF16494.5 KKK43225.1 - 0.58 10.6 0.0 0.58 10.6 0.0 3.0 3 1 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain AI-2E_transport PF01594.16 KKK43225.1 - 0.86 8.7 7.3 1.8 7.6 4.4 2.4 2 0 0 2 2 2 0 AI-2E family transporter Sec34 PF04136.15 KKK43225.1 - 0.89 9.4 5.1 15 5.4 0.6 2.9 2 0 0 2 2 2 0 Sec34-like family TBCC_N PF16752.5 KKK43225.1 - 0.91 10.0 9.0 1.6 9.2 0.0 3.6 3 1 1 4 4 4 0 Tubulin-specific chaperone C N-terminal domain TMPIT PF07851.13 KKK43225.1 - 2 7.6 8.8 4.2 6.5 0.7 2.4 2 0 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.10 KKK43225.1 - 2.2 8.5 12.3 11 6.2 0.3 3.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Tweety PF04906.13 KKK43225.1 - 2.2 6.9 9.8 0.46 9.1 4.9 2.2 2 0 0 2 2 2 0 Tweety DASH_Dad1 PF08649.10 KKK43225.1 - 4.2 7.6 7.7 40 4.5 0.2 4.7 3 1 1 4 4 4 0 DASH complex subunit Dad1 ADIP PF11559.8 KKK43225.1 - 8.4 6.5 9.2 18 5.4 0.9 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding HATPase_c PF02518.26 KKK43226.1 - 9.6e-16 58.3 0.1 2.4e-15 57.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK43226.1 - 1.8e-05 24.5 7.5 1.9e-05 24.5 1.2 2.9 2 1 1 3 3 3 1 GHKL domain HisKA PF00512.25 KKK43226.1 - 0.0017 18.3 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KKK43226.1 - 0.0028 17.6 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HhH-GPD PF00730.25 KKK43227.1 - 3.3e-12 46.8 0.0 1e-11 45.2 0.0 1.8 1 1 1 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NOG1_N PF17835.1 KKK43227.1 - 0.021 14.8 0.4 0.59 10.1 0.1 2.5 1 1 1 2 2 2 0 NOG1 N-terminal helical domain Radical_SAM PF04055.21 KKK43228.1 - 5.5e-23 82.2 0.3 8.1e-22 78.4 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 KKK43228.1 - 1.8e-12 47.3 0.0 3.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Radical_SAM_N PF08497.10 KKK43228.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Radical SAM N-terminal FGase PF05013.12 KKK43230.1 - 3.1e-06 27.5 0.0 0.0043 17.3 0.0 2.9 1 1 1 2 2 2 2 N-formylglutamate amidohydrolase CARM1 PF11531.8 KKK43231.1 - 0.0073 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Coactivator-associated arginine methyltransferase 1 N terminal DUF3876 PF12992.7 KKK43231.1 - 0.11 12.6 0.2 0.28 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) tRNA-synt_1 PF00133.22 KKK43235.1 - 7e-63 212.8 4.3 1.4e-44 152.4 0.5 3.1 3 0 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKK43235.1 - 5e-25 88.1 7.7 2.3e-10 39.8 0.0 3.8 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KKK43235.1 - 1.5e-10 40.9 2.0 0.00011 21.7 0.0 3.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KKK43235.1 - 2.9e-07 30.6 0.5 1.4e-06 28.4 0.5 2.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KKK43235.1 - 1.3e-06 28.0 0.9 3.2e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 KKK43235.1 - 2.4e-06 26.7 0.0 0.0074 15.3 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1d PF00750.19 KKK43235.1 - 0.00068 18.7 0.0 0.0044 16.0 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.25 KKK43235.1 - 0.013 14.8 0.2 0.05 12.9 0.2 2.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) PAS_3 PF08447.12 KKK43236.1 - 6.4e-37 125.7 0.3 5.5e-17 61.8 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KKK43236.1 - 1.6e-26 92.6 1.3 5.8e-10 39.2 0.0 4.7 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 KKK43236.1 - 4.5e-25 87.9 12.5 6.3e-09 36.0 0.2 4.5 4 0 0 4 4 4 4 PAS domain HATPase_c PF02518.26 KKK43236.1 - 2.8e-24 85.8 0.4 2.8e-24 85.8 0.4 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 KKK43236.1 - 3e-16 59.6 0.0 4.5e-07 30.1 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 KKK43236.1 - 5.3e-14 51.9 0.9 0.0023 17.9 0.1 4.5 4 0 0 4 4 4 4 PAS domain HisKA PF00512.25 KKK43236.1 - 9.9e-10 38.3 0.6 3e-09 36.8 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 KKK43236.1 - 7.9e-08 32.4 0.0 2.3e-05 24.5 0.0 3.4 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 KKK43236.1 - 0.0086 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK43236.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Aminotran_3 PF00202.21 KKK43237.1 - 8.3e-73 245.4 0.0 1.2e-72 244.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DUF1158 PF06643.11 KKK43238.1 - 0.057 13.9 2.3 0.057 13.9 2.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1158) Bac_export_2 PF01312.19 KKK43238.1 - 0.95 8.6 4.2 1.2 8.3 4.2 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Ac76 PF05814.11 KKK43238.1 - 6.6 6.8 11.0 12 5.9 3.1 3.1 2 1 0 2 2 2 0 Orf76 (Ac76) Peptidase_M23 PF01551.22 KKK43239.1 - 9.8e-07 28.9 0.0 2.6e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M23 YajC PF02699.15 KKK43239.1 - 0.078 12.9 0.0 0.54 10.2 0.0 2.4 3 0 0 3 3 3 0 Preprotein translocase subunit GTP_EFTU PF00009.27 KKK43242.1 - 1.3e-36 125.9 0.0 1.6e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LRR_8 PF13855.6 KKK43243.1 - 1.6e-08 34.2 1.3 7.4e-08 32.0 1.3 1.8 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KKK43243.1 - 4.7e-06 26.8 1.0 0.003 17.9 0.2 2.2 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK43243.1 - 0.0029 17.9 2.9 4.2 8.3 1.0 3.1 2 1 0 2 2 2 2 Leucine Rich Repeat HATPase_c PF02518.26 KKK43246.1 - 6.1e-16 58.9 0.0 1.1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC2_membrane PF01061.24 KKK43246.1 - 0.075 12.4 15.2 0.12 11.8 15.2 1.3 1 0 0 1 1 1 0 ABC-2 type transporter NnrS PF05940.12 KKK43246.1 - 0.18 11.1 9.8 0.08 12.3 4.2 2.0 1 1 1 2 2 2 0 NnrS protein Yip1 PF04893.17 KKK43246.1 - 2.7 7.7 16.7 0.54 10.0 11.0 2.3 2 1 0 2 2 2 0 Yip1 domain DUF2569 PF10754.9 KKK43246.1 - 5.6 7.4 18.8 40 4.6 4.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) tRNA_NucTransf2 PF09249.11 KKK43247.1 - 6.1e-22 78.0 0.2 1.5e-21 76.7 0.2 1.7 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain SMODS PF18144.1 KKK43247.1 - 0.029 14.5 0.8 0.14 12.3 0.2 2.2 2 0 0 2 2 2 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain GTP_EFTU PF00009.27 KKK43248.1 - 1.4e-30 106.3 0.1 4.7e-30 104.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 KKK43248.1 - 4.6e-27 93.7 0.2 1.4e-26 92.2 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 IF-2 PF11987.8 KKK43248.1 - 1.6e-21 76.4 3.5 2.3e-21 75.9 1.2 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KKK43248.1 - 3.1e-06 27.5 0.9 4.3e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK43248.1 - 1.1e-05 25.5 0.2 4.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KKK43248.1 - 0.00041 20.2 0.0 0.0008 19.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Roc PF08477.13 KKK43248.1 - 0.018 15.2 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sec23_helical PF04815.15 KKK43248.1 - 0.019 14.7 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 helical domain UvrA_inter PF17760.1 KKK43249.1 - 2e-35 121.1 3.9 5.7e-35 119.7 3.9 1.8 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 KKK43249.1 - 8e-21 74.5 0.2 3.2e-20 72.5 0.0 2.2 2 0 0 2 2 1 1 UvrA DNA-binding domain ABC_tran PF00005.27 KKK43249.1 - 1.1e-16 61.6 4.1 4.2e-08 33.8 0.3 4.7 4 2 0 4 4 3 2 ABC transporter SMC_N PF02463.19 KKK43249.1 - 2.7e-07 30.3 2.8 0.095 12.1 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KKK43249.1 - 1.4e-05 25.5 0.0 0.066 13.6 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 KKK43249.1 - 1.9e-05 24.6 2.7 1.7 8.4 0.2 4.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KKK43249.1 - 2.8e-05 23.8 0.2 0.16 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KKK43249.1 - 5.1e-05 23.2 0.2 0.35 10.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DnaJ_CXXCXGXG PF00684.19 KKK43249.1 - 0.0001 22.6 7.6 0.015 15.6 0.3 3.8 4 0 0 4 4 3 1 DnaJ central domain AAA_25 PF13481.6 KKK43249.1 - 0.00031 20.4 0.0 0.17 11.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KKK43249.1 - 0.001 18.9 0.4 2.1 8.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 KKK43249.1 - 0.0012 18.2 0.0 1.1 8.6 0.0 2.8 2 0 0 2 2 2 2 KaiC AAA_22 PF13401.6 KKK43249.1 - 0.0016 18.7 2.5 0.55 10.5 0.1 3.5 3 1 0 3 3 2 1 AAA domain ComA PF02679.15 KKK43249.1 - 0.0023 17.5 0.3 0.29 10.6 0.0 2.9 3 0 0 3 3 3 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2075 PF09848.9 KKK43249.1 - 0.0047 16.2 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 KKK43249.1 - 0.012 15.3 0.3 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KKK43249.1 - 0.013 16.0 0.2 5 7.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 KKK43249.1 - 0.021 15.0 0.2 1.1 9.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KKK43249.1 - 0.032 14.1 0.1 0.65 9.9 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KKK43249.1 - 0.032 14.7 11.3 1.1 9.7 0.3 4.1 4 0 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.18 KKK43249.1 - 0.039 13.7 0.1 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CpXC PF14353.6 KKK43249.1 - 0.044 13.8 0.5 17 5.5 0.0 3.1 3 0 0 3 3 2 0 CpXC protein APS_kinase PF01583.20 KKK43249.1 - 0.048 13.5 0.1 2 8.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_14 PF13173.6 KKK43249.1 - 0.068 13.2 5.7 7.8 6.5 0.0 4.7 4 1 1 5 5 5 0 AAA domain PhoH PF02562.16 KKK43249.1 - 0.072 12.5 0.1 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 KKK43249.1 - 0.11 12.2 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KKK43249.1 - 0.14 11.6 0.1 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1_C PF08438.10 KKK43249.1 - 0.19 12.3 0.9 5 7.7 0.3 2.9 3 0 0 3 3 2 0 GTPase of unknown function C-terminal AAA_30 PF13604.6 KKK43249.1 - 0.22 11.2 0.1 29 4.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain YhfH PF14149.6 KKK43249.1 - 0.45 10.5 3.6 3.2 7.8 0.2 3.3 3 0 0 3 3 2 0 YhfH-like protein Anti-TRAP PF15777.5 KKK43249.1 - 1.8 8.6 13.0 4.1 7.5 0.3 4.3 4 1 0 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_Tnp_IS1595 PF12760.7 KKK43249.1 - 8.1 6.5 5.8 19 5.3 0.1 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain UvrB_inter PF17757.1 KKK43250.1 - 3e-31 107.4 1.3 1.5e-30 105.2 0.3 2.6 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 KKK43250.1 - 1.4e-20 72.8 0.6 4.2e-20 71.3 0.6 1.9 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 KKK43250.1 - 3.2e-18 66.1 0.2 1.5e-17 63.9 0.2 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK43250.1 - 3.8e-11 43.3 0.4 4.1e-10 39.9 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UVR PF02151.19 KKK43250.1 - 6.7e-07 28.9 2.0 6.7e-07 28.9 2.0 3.0 2 0 0 2 2 2 1 UvrB/uvrC motif DEAD PF00270.29 KKK43250.1 - 4.5e-05 23.3 0.0 0.0017 18.2 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KKK43250.1 - 4.5e-05 23.3 0.0 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK43250.1 - 9.4e-05 22.7 0.1 0.082 13.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KKK43250.1 - 0.0025 18.0 3.5 0.058 13.5 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_19 PF13245.6 KKK43250.1 - 0.0047 17.3 0.1 0.13 12.6 0.0 2.7 3 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 KKK43250.1 - 0.0071 16.2 2.6 0.43 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK43250.1 - 0.011 15.3 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 KKK43250.1 - 0.11 12.9 0.0 0.51 10.8 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KKK43250.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain STT3 PF02516.14 KKK43251.1 - 2e-51 175.5 35.3 3.3e-51 174.7 35.3 1.3 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 KKK43251.1 - 1.6e-08 34.9 11.9 1.6e-08 34.9 11.9 3.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase LTD PF00932.19 KKK43251.1 - 0.014 15.7 16.8 0.52 10.7 0.2 4.1 2 2 1 4 4 4 0 Lamin Tail Domain DUF1573 PF07610.11 KKK43251.1 - 0.051 13.6 0.8 1.9 8.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1573) Tom7 PF08038.12 KKK43251.1 - 0.069 12.8 1.5 0.19 11.4 1.5 1.7 1 0 0 1 1 1 0 TOM7 family PseudoU_synth_1 PF01416.20 KKK43252.1 - 3.9e-18 65.9 0.0 1.2e-17 64.3 0.0 1.8 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2779 PF11074.8 KKK43252.1 - 0.042 14.3 0.1 0.075 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Na_Ca_ex_C PF16494.5 KKK43252.1 - 0.11 12.9 0.3 0.22 12.0 0.3 1.4 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Rep_fac_C PF08542.11 KKK43253.1 - 7.9e-18 64.7 0.3 2.5e-17 63.1 0.3 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KKK43253.1 - 9.4e-17 61.3 0.1 1e-13 51.4 0.1 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KKK43253.1 - 1.1e-14 55.0 0.0 2.5e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK43253.1 - 5e-06 26.8 0.1 0.054 13.8 0.0 2.8 2 1 1 3 3 3 2 AAA domain PhoH PF02562.16 KKK43253.1 - 2.5e-05 23.9 0.1 0.045 13.2 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_14 PF13173.6 KKK43253.1 - 2.5e-05 24.3 0.0 0.00017 21.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK43253.1 - 4.3e-05 23.3 0.0 0.00033 20.4 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KKK43253.1 - 0.00021 21.7 0.0 0.045 14.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KKK43253.1 - 0.00049 20.1 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KKK43253.1 - 0.00054 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KKK43253.1 - 0.00057 19.8 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKK43253.1 - 0.00091 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KKK43253.1 - 0.0012 18.8 0.0 0.0049 16.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KKK43253.1 - 0.0027 16.8 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KKK43253.1 - 0.0034 17.1 0.1 0.019 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KKK43253.1 - 0.0056 16.4 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KKK43253.1 - 0.0062 16.3 0.1 1.4 8.6 0.0 2.4 1 1 0 2 2 2 1 DEAD/DEAH box helicase DNA_pol3_delta PF06144.13 KKK43253.1 - 0.0065 16.3 0.1 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit TniB PF05621.11 KKK43253.1 - 0.0079 15.6 0.0 2.2 7.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 KKK43253.1 - 0.014 15.7 0.1 0.37 11.1 0.0 2.2 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KKK43253.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KKK43253.1 - 0.018 14.5 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KKK43253.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 KKK43253.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 KKK43253.1 - 0.022 14.3 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 KKK43253.1 - 0.024 13.9 0.0 0.39 9.9 0.0 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KKK43253.1 - 0.025 14.3 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KKK43253.1 - 0.039 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 KKK43253.1 - 0.08 12.9 0.2 2.4 8.0 0.0 2.5 2 1 1 3 3 2 0 NTPase AAA_25 PF13481.6 KKK43253.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK43253.1 - 0.16 11.9 0.0 2.1 8.2 0.0 2.2 1 1 0 1 1 1 0 NACHT domain CbiA PF01656.23 KKK43253.1 - 0.62 10.1 2.5 6.5 6.8 2.5 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Enolase_C PF00113.22 KKK43254.1 - 5.8e-119 396.7 0.2 8.4e-119 396.2 0.2 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KKK43254.1 - 9.4e-50 168.2 0.1 2.3e-49 166.9 0.1 1.7 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KKK43254.1 - 0.0024 17.5 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KKK43254.1 - 0.0039 16.4 0.0 0.0092 15.2 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MTS PF05175.14 KKK43255.1 - 1.4e-07 31.3 0.0 2.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KKK43255.1 - 1.4e-06 27.9 0.0 1.8e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 KKK43255.1 - 2.8e-06 27.2 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 KKK43255.1 - 0.00042 19.9 0.1 0.00096 18.8 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KKK43255.1 - 0.0078 16.9 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK43255.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KKK43255.1 - 0.01 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 KKK43255.1 - 0.065 13.0 0.0 0.26 11.0 0.0 1.8 1 1 1 2 2 2 0 Lysine methyltransferase S1 PF00575.23 KKK43256.1 - 0.00069 19.9 0.1 0.0034 17.7 0.0 2.0 2 0 0 2 2 2 1 S1 RNA binding domain DUF1451 PF07295.11 KKK43256.1 - 0.0028 17.7 0.2 0.04 14.0 0.1 2.0 1 1 1 2 2 2 1 Zinc-ribbon containing domain HypA PF01155.19 KKK43256.1 - 0.0035 17.3 1.2 0.0082 16.2 1.2 1.7 1 1 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EXOSC1 PF10447.9 KKK43256.1 - 0.0048 17.5 0.1 0.6 10.7 0.0 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 zf-FPG_IleRS PF06827.14 KKK43256.1 - 0.0094 15.8 0.9 0.19 11.6 1.1 2.4 1 1 1 2 2 2 1 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 KKK43256.1 - 0.012 15.7 1.5 0.032 14.3 1.5 1.7 1 1 0 1 1 1 0 Zinc ribbon domain TackOD1 PF18551.1 KKK43256.1 - 0.036 13.7 0.2 0.058 13.1 0.2 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 OrfB_Zn_ribbon PF07282.11 KKK43256.1 - 0.088 12.7 1.1 0.17 11.8 1.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain ECR1_N PF14382.6 KKK43256.1 - 0.11 12.3 0.0 0.44 10.4 0.0 2.0 1 1 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region TF_Zn_Ribbon PF08271.12 KKK43256.1 - 0.12 12.0 3.5 0.24 10.9 0.1 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding DZR PF12773.7 KKK43256.1 - 0.12 12.4 0.7 0.2 11.7 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KKK43256.1 - 0.15 12.1 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-IS66 PF13005.7 KKK43256.1 - 0.26 11.7 1.7 3.3 8.2 0.1 2.9 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-TFIIB PF13453.6 KKK43256.1 - 0.36 10.2 1.6 1.3 8.4 1.5 1.9 1 1 1 2 2 2 0 Transcription factor zinc-finger DUF2067 PF09840.9 KKK43257.1 - 0.00028 20.5 0.2 0.00031 20.4 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) Mistic PF11458.8 KKK43257.1 - 0.013 15.5 0.4 0.016 15.1 0.4 1.3 1 1 0 1 1 1 0 Membrane-integrating protein Mistic MOEP19 PF16005.5 KKK43257.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 KH-like RNA-binding domain RNA_pol_L_2 PF13656.6 KKK43258.1 - 2.5e-06 27.2 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribonucleas_3_2 PF11469.8 KKK43259.1 - 9.2e-21 74.5 0.3 1.3e-20 74.0 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease III Ribonuclease_3 PF00636.26 KKK43259.1 - 0.0049 17.5 0.3 0.062 13.9 0.3 2.1 1 1 0 1 1 1 1 Ribonuclease III domain Fe-S_assembly PF04384.13 KKK43259.1 - 0.04 14.5 0.1 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 Iron-sulphur cluster assembly DUF99 PF01949.16 KKK43260.1 - 3.8e-42 143.8 0.1 4.6e-42 143.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF99 Ubie_methyltran PF01209.18 KKK43260.1 - 0.085 12.2 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family INPP5B_PH PF16776.5 KKK43260.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Arf PF00025.21 KKK43261.1 - 2.2e-17 63.0 0.0 2.6e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK43261.1 - 1.6e-09 38.0 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK43261.1 - 7e-07 29.0 0.0 8.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 KKK43261.1 - 0.00098 18.7 0.0 0.001 18.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK43261.1 - 0.033 14.3 0.0 0.085 12.9 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase G-7-MTase PF12803.7 KKK43261.1 - 0.057 12.6 0.0 0.069 12.3 0.0 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) GTP_EFTU PF00009.27 KKK43262.1 - 1.2e-50 171.8 0.0 6.1e-50 169.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KKK43262.1 - 1.2e-33 115.8 0.1 3.1e-33 114.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KKK43262.1 - 7.8e-16 58.2 0.5 3.2e-15 56.3 0.5 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK43262.1 - 0.00011 22.2 0.1 0.00064 19.8 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KKK43262.1 - 0.00029 20.7 0.4 0.00029 20.7 0.4 2.7 4 0 0 4 4 4 1 Elongation factor Tu domain 4 Dynamin_N PF00350.23 KKK43262.1 - 0.15 12.1 0.0 3.3 7.7 0.0 2.5 1 1 1 2 2 2 0 Dynamin family EIF_2_alpha PF07541.12 KKK43263.1 - 5.6e-16 58.7 1.0 1.1e-15 57.7 1.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KKK43263.1 - 1.7e-09 37.9 1.3 1.7e-09 37.9 1.3 2.8 2 2 1 3 3 3 1 S1 RNA binding domain HNOB PF07700.15 KKK43263.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Haem-NO-binding Nop10p PF04135.12 KKK43264.1 - 6.9e-15 54.8 0.9 8.3e-15 54.6 0.9 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ribosomal_S27e PF01667.17 KKK43264.1 - 0.028 14.1 1.0 0.049 13.3 1.0 1.4 1 1 0 1 1 1 0 Ribosomal protein S27 zf-ribbon_3 PF13248.6 KKK43264.1 - 0.036 13.5 3.5 0.1 12.0 3.5 1.7 1 1 0 1 1 1 0 zinc-ribbon domain HIPIP PF01355.17 KKK43264.1 - 0.049 14.0 0.5 0.067 13.5 0.5 1.2 1 0 0 1 1 1 0 High potential iron-sulfur protein YpjP PF14005.6 KKK43265.1 - 0.65 10.0 5.7 0.42 10.7 0.7 2.3 2 1 0 2 2 2 0 YpjP-like protein DNA_primase_S PF01896.19 KKK43266.1 - 1.4e-17 64.3 0.1 7.4e-17 62.0 0.1 2.2 1 1 0 1 1 1 1 DNA primase small subunit TackOD1 PF18551.1 KKK43266.1 - 0.0099 15.6 0.6 0.016 14.9 0.6 1.3 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 zf-ribbon_3 PF13248.6 KKK43266.1 - 0.56 9.7 7.2 0.04 13.3 1.5 2.0 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 KKK43266.1 - 0.77 9.8 4.5 1.5 8.8 4.5 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KKK43266.1 - 3.2 7.8 7.0 5.4 7.1 7.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KKK43266.1 - 4.4 7.4 9.4 5.4 7.1 0.9 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin_2 PF18073.1 KKK43266.1 - 6.1 6.7 13.8 0.064 13.0 2.5 2.7 2 1 1 3 3 3 0 Rubredoxin metal binding domain zf-C3HC4_3 PF13920.6 KKK43266.1 - 7.9 6.4 7.4 1 9.2 2.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DNA_primase_lrg PF04104.14 KKK43267.1 - 6.6e-24 84.7 6.4 1.2e-23 83.8 6.4 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PAS_10 PF13596.6 KKK43268.1 - 1.5e-26 93.1 0.1 3.4e-26 91.9 0.1 1.6 1 0 0 1 1 1 1 PAS domain Hemerythrin PF01814.23 KKK43268.1 - 1.9e-14 54.4 2.5 1e-13 52.0 2.5 2.1 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain PAS_4 PF08448.10 KKK43268.1 - 0.00061 20.0 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold HEPN_Cthe2314 PF18730.1 KKK43268.1 - 0.94 9.5 5.1 0.53 10.3 2.2 1.9 2 0 0 2 2 2 0 Cthe_2314-like HEPN Beta-lactamase PF00144.24 KKK43272.1 - 4.8e-59 200.2 0.0 6.2e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase ECH_1 PF00378.20 KKK43273.1 - 1.2e-44 152.6 0.0 1.3e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK43273.1 - 3.1e-14 53.2 0.0 4.3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Usp PF00582.26 KKK43274.1 - 9.7e-22 78.0 0.1 2e-21 77.0 0.1 1.5 1 1 0 1 1 1 1 Universal stress protein family DUF2853 PF11015.8 KKK43274.1 - 0.053 14.2 0.4 0.093 13.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) DASH_Dad4 PF08650.10 KKK43274.1 - 0.068 13.1 0.1 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad4 Adeno_E1B_19K PF01691.16 KKK43274.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen AP_endonuc_2 PF01261.24 KKK43274.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TPR_8 PF13181.6 KKK43274.1 - 0.17 12.1 1.3 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD-oxidase_C PF02913.19 KKK43277.1 - 2.5e-22 79.7 0.1 3.8e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Fer4_17 PF13534.6 KKK43277.1 - 1.9e-10 41.1 4.4 3.8e-10 40.1 4.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK43277.1 - 3.3e-10 40.3 2.6 6e-10 39.4 2.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK43277.1 - 3.1e-08 34.1 1.9 6e-08 33.2 1.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK43277.1 - 4e-06 26.4 7.5 0.0078 16.0 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK43277.1 - 1.1e-05 25.5 8.4 0.00046 20.2 10.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43277.1 - 1.7e-05 24.8 3.4 0.053 13.7 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43277.1 - 2.5e-05 24.4 5.6 0.00042 20.4 6.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43277.1 - 5e-05 24.2 2.2 0.00012 22.9 2.2 1.7 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KKK43277.1 - 0.00067 19.6 10.4 0.014 15.5 1.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KKK43277.1 - 0.0012 19.7 1.8 0.34 11.8 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK43277.1 - 0.0021 18.4 9.5 0.022 15.2 1.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 KKK43277.1 - 0.011 15.9 3.0 1.7 8.9 0.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43277.1 - 0.011 15.8 8.0 0.48 10.6 1.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain MTHFR_C PF12225.8 KKK43277.1 - 0.037 13.7 3.6 3 7.6 0.3 2.3 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal Fer4_3 PF12798.7 KKK43277.1 - 0.068 14.1 2.7 0.068 14.1 2.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK43277.1 - 9.4 6.9 7.5 24 5.5 0.5 2.6 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Lar_N PF09861.9 KKK43278.1 - 6.4e-64 214.9 0.0 9.7e-64 214.3 0.0 1.3 1 0 0 1 1 1 1 Lactate racemase N-terminal domain Jag_N PF14804.6 KKK43278.1 - 0.09 13.1 0.1 0.25 11.7 0.1 1.8 1 0 0 1 1 1 0 Jag N-terminus Abhydrolase_3 PF07859.13 KKK43279.1 - 2.5e-07 30.8 0.0 9.7e-05 22.3 0.0 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold COesterase PF00135.28 KKK43279.1 - 0.00023 20.2 0.5 0.00034 19.6 0.5 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KKK43279.1 - 0.025 14.1 0.3 8 5.9 0.1 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family TFIIB PF00382.19 KKK43280.1 - 1.7e-26 92.1 0.1 2.6e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat RB_B PF01857.20 KKK43280.1 - 3.2e-05 24.0 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain G3P_acyltransf PF02660.15 KKK43281.1 - 4.5e-33 114.6 20.3 4.5e-33 114.6 20.3 2.9 1 1 1 2 2 2 1 Glycerol-3-phosphate acyltransferase SurA_N_3 PF13624.6 KKK43281.1 - 0.084 12.7 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 SurA N-terminal domain DUF3864 PF12980.7 KKK43282.1 - 0.013 15.8 0.2 0.11 12.8 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) SepF PF04472.12 KKK43282.1 - 0.038 14.3 0.1 1.8 8.9 0.0 2.7 2 1 0 2 2 2 0 Cell division protein SepF Methyltransf_31 PF13847.6 KKK43282.1 - 0.066 13.0 0.1 0.066 13.0 0.1 2.3 1 1 1 2 2 2 0 Methyltransferase domain tRNA-synt_2b PF00587.25 KKK43283.1 - 2.7e-22 79.6 0.0 1.5e-21 77.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KKK43283.1 - 1.1e-15 57.6 0.4 2.2e-15 56.5 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.11 KKK43283.1 - 3.8e-08 33.4 2.7 9e-08 32.2 2.7 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal DUF2387 PF09526.10 KKK43284.1 - 0.037 14.2 0.2 0.04 14.1 0.2 1.1 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF35_N PF12172.8 KKK43284.1 - 0.077 12.9 1.8 3.9 7.4 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Lactamase_B PF00753.27 KKK43285.1 - 3.4e-15 56.6 0.0 5.8e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK43285.1 - 0.0005 19.6 0.0 0.00074 19.1 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Nitroreductase PF00881.24 KKK43286.1 - 3.8e-33 114.9 1.9 6.9e-18 65.3 0.3 2.0 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 KKK43286.1 - 4e-17 62.5 1.8 4e-07 29.8 0.0 3.1 1 1 2 3 3 3 3 Putative TM nitroreductase HMGL-like PF00682.19 KKK43288.1 - 1.9e-81 273.5 0.0 3.3e-81 272.7 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KKK43288.1 - 5.4e-28 97.5 0.1 9e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Aconitase PF00330.20 KKK43289.1 - 2.4e-93 313.7 0.3 6.8e-92 308.9 0.3 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KKK43290.1 - 5.4e-20 72.1 0.0 7.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KKK43290.1 - 9.4e-06 25.4 0.0 0.0013 18.4 0.0 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus FAD_syn PF06574.12 KKK43290.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD synthetase Apolipoprotein PF01442.18 KKK43291.1 - 6.7e-11 42.4 15.8 1.8e-08 34.5 3.3 3.4 3 0 0 3 3 3 2 Apolipoprotein A1/A4/E domain KMP11 PF03037.16 KKK43291.1 - 0.0021 18.8 2.2 0.0021 18.8 2.2 4.4 4 2 1 5 5 5 1 Kinetoplastid membrane protein 11 Exonuc_VII_L PF02601.15 KKK43291.1 - 0.0038 16.9 10.0 0.0038 16.9 10.0 4.0 1 1 2 3 3 3 2 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 KKK43291.1 - 0.0045 17.0 3.4 0.0045 17.0 3.4 5.7 3 2 4 7 7 7 4 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 KKK43291.1 - 0.011 15.8 33.2 0.034 14.2 9.3 4.4 2 2 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 KKK43291.1 - 0.019 15.5 16.3 1.5 9.4 1.4 5.6 3 3 4 7 7 7 0 Bacterial protein of unknown function (DUF883) Lant_dehydr_C PF14028.6 KKK43291.1 - 0.024 14.2 3.2 0.042 13.4 0.5 2.5 2 1 1 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term DUF1657 PF07870.11 KKK43291.1 - 0.092 12.6 3.3 5 7.1 0.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1657) CdvA PF18822.1 KKK43291.1 - 0.092 12.6 30.6 0.48 10.3 2.6 6.4 4 2 1 5 5 5 0 CdvA-like coiled-coil domain Consortin_C PF15281.6 KKK43291.1 - 0.12 12.3 0.6 0.37 10.8 0.1 2.1 2 0 0 2 2 2 0 Consortin C-terminus Tape_meas_lam_C PF09718.10 KKK43291.1 - 0.15 12.2 10.0 0.39 10.9 0.1 4.8 4 1 1 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF885 PF05960.11 KKK43291.1 - 0.95 9.0 10.7 2.8 7.5 4.5 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF885) CK2S PF15011.6 KKK43291.1 - 1.1 9.1 7.4 0.21 11.5 1.8 2.7 3 0 0 3 3 3 0 Casein Kinase 2 substrate DUF2894 PF11445.8 KKK43291.1 - 1.9 8.9 7.0 7.9 6.9 0.6 3.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2894) Prominin PF05478.11 KKK43291.1 - 2.6 5.9 41.4 0.0081 14.2 16.7 2.9 1 1 3 4 4 4 0 Prominin YtxH PF12732.7 KKK43291.1 - 3.3 8.3 24.0 89 3.7 3.1 6.8 1 1 1 2 2 1 0 YtxH-like protein TipAS PF07739.13 KKK43291.1 - 7.1 7.2 8.2 14 6.2 0.4 4.2 2 2 1 3 3 3 0 TipAS antibiotic-recognition domain ubiquitin PF00240.23 KKK43293.1 - 4.5e-05 23.1 0.5 0.00047 19.9 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KKK43293.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like EI24 PF07264.11 KKK43293.1 - 0.081 13.2 0.3 0.72 10.1 0.0 2.2 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Rad60-SLD_2 PF13881.6 KKK43293.1 - 0.16 12.1 0.0 0.61 10.2 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like AI-2E_transport PF01594.16 KKK43293.1 - 1.9 7.6 6.7 0.65 9.1 0.1 2.8 2 1 1 3 3 3 0 AI-2E family transporter CAAD PF14159.6 KKK43293.1 - 2.5 8.0 4.0 1.2 9.0 0.5 2.3 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PBP_dimer PF03717.15 KKK43296.1 - 0.23 11.8 1.6 0.44 10.9 1.6 1.7 1 1 0 1 1 1 0 Penicillin-binding Protein dimerisation domain MobB PF03205.14 KKK43297.1 - 1.2e-23 83.5 0.1 1.4e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KKK43297.1 - 3.9e-05 23.3 0.2 6.9e-05 22.5 0.2 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 KKK43297.1 - 0.0038 17.3 0.4 0.006 16.6 0.4 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.18 KKK43297.1 - 0.0091 15.5 0.7 0.011 15.3 0.7 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B NACHT PF05729.12 KKK43297.1 - 0.011 15.7 0.1 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 NACHT domain PRK PF00485.18 KKK43297.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KKK43297.1 - 0.025 14.8 0.1 0.029 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKK43297.1 - 0.025 15.1 0.1 0.03 14.9 0.1 1.2 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 KKK43297.1 - 0.029 14.3 1.2 0.045 13.7 1.2 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KKK43297.1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KKK43297.1 - 0.067 13.0 0.2 0.13 12.1 0.1 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 KKK43297.1 - 0.069 12.8 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF463 PF04317.12 KKK43297.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_16 PF13191.6 KKK43297.1 - 0.089 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KKK43297.1 - 0.1 12.9 0.2 0.24 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Acylphosphatase PF00708.18 KKK43297.1 - 0.1 13.0 0.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 Acylphosphatase AAA_18 PF13238.6 KKK43297.1 - 0.11 13.1 0.3 0.2 12.2 0.3 1.7 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KKK43297.1 - 0.11 11.5 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 KKK43297.1 - 0.12 12.7 0.0 0.27 11.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AIRS_C PF02769.22 KKK43299.1 - 8.1e-19 68.3 0.0 1.3e-18 67.6 0.0 1.3 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain PAS_9 PF13426.7 KKK43304.1 - 6e-10 39.3 0.2 1.7e-09 37.9 0.2 1.8 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 KKK43304.1 - 1.7e-08 34.3 0.6 6.1e-08 32.6 0.0 2.3 2 2 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KKK43304.1 - 2.1e-08 34.2 0.0 1.2e-07 31.7 0.0 2.3 1 1 1 2 2 2 1 PAS fold HATPase_c PF02518.26 KKK43304.1 - 5.6e-07 30.1 0.2 1.1e-06 29.1 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KKK43304.1 - 4.5e-06 26.5 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KKK43304.1 - 0.009 16.3 0.0 0.024 14.9 0.0 1.7 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.12 KKK43304.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold HATPase_c_2 PF13581.6 KKK43304.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Holin_BhlA PF10960.8 KKK43304.1 - 0.13 12.3 5.0 0.2 11.6 0.0 3.5 3 0 0 3 3 3 0 BhlA holin family DUF4271 PF14093.6 KKK43304.1 - 0.15 11.9 6.9 0.096 12.6 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF2862 PF11061.8 KKK43304.1 - 0.61 10.0 2.7 5.5 6.9 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2862) AAA PF00004.29 KKK43306.1 - 2.1e-10 41.1 0.0 3.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KKK43306.1 - 4.9e-07 29.8 0.1 2.3e-06 27.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK43306.1 - 5.6e-06 26.8 0.2 0.00043 20.7 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KKK43306.1 - 2e-05 24.8 0.0 3.4e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KKK43306.1 - 2.4e-05 24.3 0.4 0.00039 20.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KKK43306.1 - 3.2e-05 24.2 0.0 6.5e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KKK43306.1 - 0.00017 20.9 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KKK43306.1 - 0.00029 20.3 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KKK43306.1 - 0.00076 19.2 0.1 0.0022 17.7 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 KKK43306.1 - 0.00097 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 KKK43306.1 - 0.0014 18.4 0.1 0.0072 16.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 KKK43306.1 - 0.0016 18.5 0.0 0.0045 17.1 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 KKK43306.1 - 0.003 17.6 0.0 0.0034 17.4 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DAP3 PF10236.9 KKK43306.1 - 0.0039 16.4 0.0 0.0053 16.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 KKK43306.1 - 0.0048 16.2 0.1 0.0068 15.7 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KKK43306.1 - 0.0054 17.1 0.9 0.051 13.9 0.9 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KKK43306.1 - 0.0082 16.5 0.1 0.01 16.2 0.1 1.5 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KKK43306.1 - 0.0098 15.9 0.1 0.023 14.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KKK43306.1 - 0.017 15.0 0.1 0.049 13.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KKK43306.1 - 0.019 15.5 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KKK43306.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 KKK43306.1 - 0.021 14.8 0.2 0.058 13.4 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KKK43306.1 - 0.023 14.4 0.1 0.057 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK43306.1 - 0.023 14.6 0.8 0.18 11.7 0.8 2.1 1 1 0 1 1 1 0 NTPase IstB_IS21 PF01695.17 KKK43306.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 KKK43306.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KKK43306.1 - 0.037 13.8 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KKK43306.1 - 0.037 13.9 0.3 0.2 11.6 0.3 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 KKK43306.1 - 0.046 12.8 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 T2SSE PF00437.20 KKK43306.1 - 0.066 12.3 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 KKK43306.1 - 0.067 13.0 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KKK43306.1 - 0.073 12.2 0.0 0.086 12.0 0.0 1.3 1 1 0 1 1 1 0 PIF1-like helicase PhoH PF02562.16 KKK43306.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 KKK43306.1 - 0.14 12.3 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 KKK43306.1 - 0.15 11.0 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Zeta_toxin PF06414.12 KKK43306.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Thiolase_C PF02803.18 KKK43307.1 - 1e-11 44.5 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Phage_T4_gp19 PF06841.12 KKK43309.1 - 0.027 14.3 0.2 4.6 7.1 0.0 2.1 1 1 1 2 2 2 0 T4-like virus tail tube protein gp19 DUF4695 PF15766.5 KKK43309.1 - 0.094 12.9 1.7 8.2 6.7 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4695) Glyoxalase PF00903.25 KKK43310.1 - 0.00093 19.4 0.0 0.017 15.3 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KKK43310.1 - 0.0033 17.3 0.1 0.011 15.7 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Succ_CoA_lig PF13607.6 KKK43311.1 - 7.3e-34 116.5 0.0 1.1e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK43311.1 - 0.0011 19.4 0.0 0.0027 18.2 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK43311.1 - 0.057 14.1 0.0 0.15 12.7 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain DUF772 PF05598.11 KKK43311.1 - 0.21 11.6 0.7 7.4 6.7 0.0 3.4 4 0 0 4 4 4 0 Transposase domain (DUF772) HSP90 PF00183.18 KKK43312.1 - 9.3e-113 377.8 39.8 9.3e-113 377.8 39.8 2.1 1 1 1 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.6 KKK43312.1 - 1.9e-10 40.7 0.1 6.3e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK43312.1 - 3.7e-06 27.4 0.1 7.5e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC24_OB1 PF17246.2 KKK43312.1 - 8.8 6.5 9.9 1.4 9.0 2.8 3.0 2 1 0 2 2 2 0 Cell division control protein 24, OB domain 1 DAG_kinase_N PF14513.6 KKK43312.1 - 9.8 6.3 13.9 0.6 10.3 1.4 3.2 3 0 0 3 3 3 0 Diacylglycerol kinase N-terminus HTH_42 PF06224.12 KKK43313.1 - 2.8e-40 138.9 0.0 3.2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain Imm6 PF14434.6 KKK43313.1 - 0.025 14.5 2.0 0.17 11.8 2.0 2.4 1 1 0 1 1 1 0 Immunity protein Imm6 GD_AH_C PF04295.13 KKK43314.1 - 3.3e-13 49.2 0.1 3.8e-13 49.0 0.1 1.0 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus adh_short PF00106.25 KKK43315.1 - 9.3e-55 185.1 0.1 2.2e-54 183.9 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK43315.1 - 1.2e-39 136.3 0.0 1.8e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK43315.1 - 1.5e-12 47.8 0.0 2.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK43315.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KKK43315.1 - 0.027 13.5 0.8 0.057 12.4 0.3 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KKK43315.1 - 0.068 12.7 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 NmrA-like family SAF PF08666.12 KKK43316.1 - 8.3e-10 39.2 0.3 1.2e-09 38.6 0.3 1.3 1 1 0 1 1 1 1 SAF domain GD_AH_C PF04295.13 KKK43317.1 - 2.2e-125 418.5 0.3 3.7e-125 417.8 0.3 1.2 1 1 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus Aldo_ket_red PF00248.21 KKK43318.1 - 1.8e-44 152.1 0.7 3.6e-44 151.1 0.7 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Fer4_17 PF13534.6 KKK43318.1 - 6e-10 39.5 6.0 1.4e-09 38.3 6.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43318.1 - 1.7e-09 37.7 5.0 3.7e-09 36.6 5.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK43318.1 - 4.5e-06 26.8 0.5 0.0064 16.7 0.1 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK43318.1 - 3.8e-05 24.0 4.4 8.4e-05 22.9 4.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK43318.1 - 0.0011 19.5 5.6 0.007 16.9 5.7 2.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43318.1 - 0.0065 16.6 9.0 0.041 14.0 1.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43318.1 - 0.01 16.7 6.1 0.065 14.2 0.7 3.0 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 KKK43318.1 - 0.016 15.3 2.0 0.016 15.3 2.0 2.6 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 KKK43318.1 - 0.02 14.7 1.8 0.02 14.7 1.8 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_20 PF14691.6 KKK43318.1 - 0.023 14.4 7.3 0.035 13.9 0.9 2.3 1 1 1 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF5333 PF17267.2 KKK43318.1 - 0.057 13.6 0.3 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5333) DUF3502 PF12010.8 KKK43318.1 - 0.095 13.3 0.8 20 5.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3502) Fer4_22 PF17179.4 KKK43318.1 - 0.26 12.2 0.2 0.26 12.2 0.2 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43318.1 - 0.29 11.3 6.5 0.73 10.0 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43318.1 - 4.6 7.5 15.1 0.59 10.3 2.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK43318.1 - 6.4 7.6 10.9 3.9 8.2 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 KKK43319.1 - 4e-09 35.9 16.1 0.00026 20.6 4.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK43319.1 - 4.4e-09 36.8 16.7 1.1e-06 29.1 9.4 2.7 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43319.1 - 9.5e-08 31.8 16.7 0.00057 19.9 5.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK43319.1 - 2.2e-07 31.0 7.3 2.2e-07 31.0 7.3 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43319.1 - 1.2e-05 25.4 18.2 1.9e-05 24.7 9.9 2.6 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43319.1 - 5.4e-05 23.2 12.5 5.4e-05 23.2 12.5 2.8 2 1 1 3 3 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43319.1 - 0.00012 22.9 16.0 0.0051 17.7 0.8 3.5 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain TrmB PF01978.19 KKK43319.1 - 0.0011 18.8 0.2 0.0026 17.6 0.2 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fer4_2 PF12797.7 KKK43319.1 - 0.0065 16.5 1.4 0.0065 16.5 1.4 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Recombinase PF07508.13 KKK43319.1 - 0.018 15.5 0.2 0.032 14.6 0.2 1.5 1 1 0 1 1 1 0 Recombinase Fer4_4 PF12800.7 KKK43319.1 - 0.024 15.1 1.8 0.024 15.1 1.8 3.4 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 KKK43319.1 - 0.026 15.0 16.5 0.052 14.0 0.5 3.4 3 0 0 3 3 3 0 4Fe-4S dicluster domain DUF4194 PF13835.6 KKK43319.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Fer4_15 PF13459.6 KKK43319.1 - 1 10.1 14.5 1.8 9.3 4.4 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 KKK43319.1 - 1.1 9.9 22.7 0.41 11.2 2.4 3.6 2 1 1 4 4 4 0 4Fe-4S dicluster domain CSD PF00313.22 KKK43320.1 - 2.1e-27 94.8 1.9 2.7e-27 94.4 1.9 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain GRP PF07172.11 KKK43320.1 - 0.0023 18.5 21.4 0.0032 18.1 21.4 1.2 1 0 0 1 1 1 1 Glycine rich protein family S1 PF00575.23 KKK43320.1 - 0.029 14.7 0.1 0.037 14.4 0.1 1.2 1 0 0 1 1 1 0 S1 RNA binding domain DUF211 PF02680.14 KKK43321.1 - 1.9e-18 66.4 2.1 2.3e-18 66.2 2.1 1.0 1 0 0 1 1 1 1 Uncharacterized ArCR, COG1888 B5 PF03484.15 KKK43321.1 - 0.018 15.3 0.3 0.042 14.1 0.3 1.7 1 1 0 1 1 1 0 tRNA synthetase B5 domain YabP PF07873.11 KKK43321.1 - 0.033 14.0 0.7 0.048 13.4 0.7 1.3 1 0 0 1 1 1 0 YabP family CitMHS PF03600.16 KKK43322.1 - 1.2e-22 80.5 49.5 7.4e-18 64.8 17.4 2.2 1 1 0 2 2 2 2 Citrate transporter ArsB PF02040.15 KKK43322.1 - 4.5e-05 23.0 41.4 5.9e-05 22.6 41.4 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein Mrr_cat_2 PF13156.6 KKK43324.1 - 0.00023 21.0 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF1492 PF07374.11 KKK43324.1 - 0.11 12.7 3.1 0.23 11.6 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) Fer4 PF00037.27 KKK43326.1 - 8.6e-13 47.5 14.4 3.4e-07 29.8 2.1 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK43326.1 - 2.3e-08 34.1 7.4 2.3e-08 34.1 7.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43326.1 - 2.4e-08 34.0 9.0 2.4e-08 34.0 9.0 2.3 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43326.1 - 1.6e-07 31.1 13.8 0.00069 19.6 4.1 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK43326.1 - 6.1e-06 26.7 23.3 0.00011 22.7 13.7 3.0 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43326.1 - 0.00015 21.6 12.9 0.00072 19.5 2.3 3.3 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK43326.1 - 0.00015 22.1 17.7 0.036 14.5 0.5 3.4 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK43326.1 - 0.00055 20.1 4.3 0.00055 20.1 4.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK43326.1 - 0.002 18.5 1.7 0.002 18.5 1.7 3.5 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK43326.1 - 0.0051 16.9 27.8 0.086 13.0 3.3 2.7 1 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK43326.1 - 0.01 16.6 0.7 0.01 16.6 0.7 2.9 2 1 1 3 3 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 KKK43326.1 - 0.015 15.8 1.3 0.015 15.8 1.3 3.2 4 0 0 4 4 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF4817 PF16087.5 KKK43326.1 - 0.016 15.0 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Fer4_16 PF13484.6 KKK43326.1 - 0.055 14.4 2.9 0.055 14.4 2.9 3.6 2 1 2 4 4 4 0 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 KKK43326.1 - 0.056 14.3 1.3 0.056 14.3 1.3 3.5 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK43326.1 - 7.4 7.2 29.9 0.31 11.6 2.3 3.4 1 1 3 4 4 2 0 4Fe-4S dicluster domain DUF3325 PF11804.8 KKK43327.1 - 0.014 15.6 0.9 0.014 15.6 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) DUF2207 PF09972.9 KKK43327.1 - 0.045 12.5 3.0 0.05 12.4 3.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF515 PF04415.12 KKK43327.1 - 0.08 11.3 0.4 0.089 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3040 PF11239.8 KKK43327.1 - 0.12 12.6 0.8 0.13 12.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) AA_permease_C PF13906.6 KKK43327.1 - 0.13 12.4 8.7 0.13 12.3 3.1 2.0 2 0 0 2 2 2 0 C-terminus of AA_permease OppC_N PF12911.7 KKK43327.1 - 0.54 10.3 13.4 0.13 12.2 3.6 2.1 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C NVEALA PF14055.6 KKK43327.1 - 6.6 6.8 5.2 14 5.7 0.2 2.1 1 1 1 2 2 2 0 NVEALA protein AMP-binding PF00501.28 KKK43328.1 - 4.2e-59 200.2 0.0 5.1e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK43328.1 - 4e-06 27.7 0.0 7.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OCRE PF17780.1 KKK43328.1 - 0.55 10.3 2.5 85 3.3 0.1 3.4 3 0 0 3 3 3 0 OCRE domain GDPD PF03009.17 KKK43330.1 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Tom6 PF17112.5 KKK43330.1 - 0.018 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal GDPD PF03009.17 KKK43331.1 - 5.3e-10 39.5 0.0 5.7e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2181 PF10223.9 KKK43331.1 - 0.16 11.4 0.0 0.18 11.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) Bac_luciferase PF00296.20 KKK43333.1 - 3.6e-17 62.8 0.0 8.8e-17 61.5 0.0 1.5 1 1 1 2 2 2 1 Luciferase-like monooxygenase Osmo_CC PF08946.10 KKK43333.1 - 0.0034 17.6 0.5 0.0079 16.4 0.5 1.6 1 0 0 1 1 1 1 Osmosensory transporter coiled coil BLI1 PF17324.2 KKK43333.1 - 0.0095 16.6 0.2 0.44 11.2 0.0 2.3 2 1 0 2 2 2 1 BLOC-1 interactor 1 MAM1 PF10434.9 KKK43333.1 - 0.028 14.0 0.1 0.033 13.8 0.1 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 FapA PF03961.13 KKK43333.1 - 0.035 12.7 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Radical_SAM PF04055.21 KKK43333.1 - 0.094 13.1 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily zf-C2H2_4 PF13894.6 KKK43334.1 - 0.0012 19.5 1.7 0.0024 18.5 1.7 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KKK43334.1 - 0.04 14.4 0.9 0.12 12.9 0.9 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KKK43334.1 - 0.055 13.4 2.2 0.093 12.7 0.1 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Methyltransf_29 PF03141.16 KKK43334.1 - 0.065 11.8 0.1 0.078 11.5 0.1 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF5603 PF18231.1 KKK43334.1 - 0.11 12.8 1.0 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5603) Cep57_CLD PF14073.6 KKK43334.1 - 0.14 12.2 1.5 0.28 11.2 1.5 1.4 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 AAA_22 PF13401.6 KKK43335.1 - 0.00026 21.3 0.0 0.14 12.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KKK43335.1 - 0.00096 18.4 0.0 0.0089 15.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_lid_7 PF17867.1 KKK43335.1 - 0.0042 17.3 0.1 0.58 10.4 0.0 2.6 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_16 PF13191.6 KKK43335.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF3744 PF12558.8 KKK43335.1 - 0.034 14.9 2.7 3.6 8.4 0.0 4.0 4 0 0 4 4 4 0 ATP-binding cassette cobalt transporter DUF5475 PF17569.2 KKK43335.1 - 0.035 14.4 0.4 0.11 12.8 0.4 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5475) Arteri_GP4 PF02497.15 KKK43335.1 - 0.15 12.2 0.5 4.1 7.5 0.0 2.5 2 1 1 3 3 3 0 Arterivirus glycoprotein Mrr_cat PF04471.12 KKK43335.1 - 0.18 11.8 0.1 0.94 9.5 0.0 2.2 3 0 0 3 3 3 0 Restriction endonuclease Ku_PK_bind PF08785.11 KKK43335.1 - 1.5 9.0 5.2 1.4 9.1 0.9 2.7 2 0 0 2 2 2 0 Ku C terminal domain like DUF87 PF01935.17 KKK43336.1 - 9e-14 52.1 2.6 7.7e-13 49.1 2.6 2.3 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 KKK43336.1 - 3.4e-08 33.9 0.0 0.013 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 KKK43336.1 - 8.5e-06 24.9 0.1 1.8e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.12 KKK43336.1 - 4.1e-05 23.3 1.0 6.9e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) ResIII PF04851.15 KKK43336.1 - 5.2e-05 23.3 1.7 0.0024 17.9 0.1 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 KKK43336.1 - 6e-05 22.0 0.0 0.0071 15.2 0.0 2.2 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer AAA_10 PF12846.7 KKK43336.1 - 0.00013 21.1 0.5 0.00035 19.6 0.1 1.9 2 0 0 2 2 2 1 AAA-like domain DUF2075 PF09848.9 KKK43336.1 - 0.001 18.4 0.2 0.87 8.8 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KKK43336.1 - 0.003 18.0 0.6 0.3 11.5 0.5 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KKK43336.1 - 0.0031 17.9 0.6 0.043 14.2 0.1 3.0 2 1 1 3 3 3 1 RNA helicase ABC_tran PF00005.27 KKK43336.1 - 0.0032 18.0 1.1 0.012 16.1 0.7 2.2 2 1 0 2 2 2 1 ABC transporter ATPase_2 PF01637.18 KKK43336.1 - 0.0036 17.2 4.2 0.019 14.9 4.2 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 KKK43336.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 KKK43336.1 - 0.036 13.7 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 KKK43336.1 - 0.15 11.5 0.1 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region MeaB PF03308.16 KKK43336.1 - 0.17 10.9 0.0 0.47 9.4 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NurA PF09376.10 KKK43337.1 - 8.5e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 NurA domain COMP PF11598.8 KKK43337.1 - 0.25 11.8 0.8 1.3 9.6 0.2 2.3 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein EMP24_GP25L PF01105.24 KKK43338.1 - 4e-07 30.2 0.4 4e-07 30.2 0.4 1.7 1 1 0 2 2 2 1 emp24/gp25L/p24 family/GOLD zinc_ribbon_15 PF17032.5 KKK43338.1 - 0.0099 16.6 0.9 0.019 15.7 0.9 1.4 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 KKK43338.1 - 0.033 14.2 0.5 0.055 13.5 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 KKK43338.1 - 0.12 12.3 0.9 5.7 7.0 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KKK43338.1 - 0.22 11.3 3.5 0.6 9.9 3.5 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KKK43338.1 - 2.8 7.7 4.3 28 4.5 1.5 2.1 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C4_Topoisom PF01396.19 KKK43339.1 - 3.5e-26 90.7 13.2 1.1e-14 53.9 1.5 2.1 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger ADK_lid PF05191.14 KKK43339.1 - 7.7e-05 22.6 2.9 0.015 15.2 0.9 2.3 2 0 0 2 2 2 2 Adenylate kinase, active site lid DZR PF12773.7 KKK43339.1 - 0.00034 20.6 0.7 0.00072 19.5 0.3 1.8 1 1 1 2 2 2 2 Double zinc ribbon Nudix_N_2 PF14803.6 KKK43339.1 - 0.00077 19.3 1.5 0.018 15.0 0.3 2.6 2 0 0 2 2 2 1 Nudix N-terminal Zn-ribbon_8 PF09723.10 KKK43339.1 - 0.0035 17.4 0.5 0.4 10.8 0.2 2.3 2 0 0 2 2 2 1 Zinc ribbon domain Auto_anti-p27 PF06677.12 KKK43339.1 - 0.01 16.0 2.7 2.6 8.3 0.5 2.5 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2256 PF10013.9 KKK43339.1 - 0.011 15.8 0.4 4.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_2 PF13240.6 KKK43339.1 - 0.014 15.1 3.6 0.77 9.6 0.6 2.9 2 0 0 2 2 2 0 zinc-ribbon domain CoiA PF06054.11 KKK43339.1 - 0.036 13.2 0.3 2.6 7.1 0.0 2.0 2 0 0 2 2 2 0 Competence protein CoiA-like family Zn_Tnp_IS1 PF03811.13 KKK43339.1 - 0.041 13.6 0.1 0.041 13.6 0.1 2.3 3 0 0 3 3 3 0 InsA N-terminal domain DNA_RNApol_7kD PF03604.13 KKK43339.1 - 0.054 13.2 2.6 0.52 10.0 0.2 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf_C2H2_13 PF18508.1 KKK43339.1 - 0.12 12.0 0.4 0.12 12.0 0.4 2.0 2 0 0 2 2 2 0 Zinc finger domain zf-ribbon_3 PF13248.6 KKK43339.1 - 0.12 11.8 7.1 2.4 7.7 2.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KKK43339.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Zn_ribbon_recom PF13408.6 KKK43339.1 - 0.21 12.1 8.2 0.23 12.0 0.6 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zinc-ribbons_6 PF07191.12 KKK43339.1 - 0.27 11.2 2.8 2 8.5 2.8 2.2 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_4 PF13717.6 KKK43339.1 - 0.28 11.2 6.8 12 6.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Ogr_Delta PF04606.12 KKK43339.1 - 0.91 9.6 8.6 0.8 9.7 1.3 3.3 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger RecR PF02132.15 KKK43339.1 - 1.6 8.3 4.8 2.8 7.6 0.5 2.3 2 0 0 2 2 2 0 RecR protein DNA_ligase_ZBD PF03119.16 KKK43339.1 - 2.2 8.3 8.9 0.4 10.8 0.9 3.0 3 1 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain bPH_4 PF06713.11 KKK43340.1 - 0.0066 16.5 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial PH domain bPH_5 PF10882.8 KKK43340.1 - 0.02 14.9 0.1 0.034 14.2 0.1 1.5 1 1 0 1 1 1 0 Bacterial PH domain bPH_2 PF03703.14 KKK43340.1 - 0.085 13.1 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial PH domain Legionella_OMP PF05150.12 KKK43340.1 - 0.16 10.9 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor DUF3093 PF11292.8 KKK43340.1 - 0.19 12.0 0.1 0.31 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) EbsA PF17255.2 KKK43340.1 - 0.2 12.0 9.5 0.47 10.8 8.1 2.1 2 1 1 3 3 3 0 EbsA-like protein DUF2207 PF09972.9 KKK43340.1 - 1.1 8.0 3.6 1.3 7.7 3.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Occludin_ELL PF07303.13 KKK43341.1 - 0.0021 18.8 0.8 0.004 17.9 0.7 1.6 1 1 0 1 1 1 1 Occludin homology domain LOH1CR12 PF10158.9 KKK43341.1 - 0.0023 18.0 0.3 0.0029 17.6 0.3 1.1 1 0 0 1 1 1 1 Tumour suppressor protein MlaC PF05494.12 KKK43341.1 - 0.0048 16.7 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 MlaC protein DUF1664 PF07889.12 KKK43341.1 - 0.0062 16.6 0.2 0.0087 16.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) EzrA PF06160.12 KKK43341.1 - 0.011 13.9 1.0 0.013 13.7 1.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 KKK43341.1 - 0.013 15.8 0.7 0.12 12.7 0.1 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FmiP_Thoc5 PF09766.9 KKK43341.1 - 0.026 13.8 0.1 0.029 13.7 0.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 YkyA PF10368.9 KKK43341.1 - 0.028 14.1 2.6 0.036 13.7 2.6 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Sec34 PF04136.15 KKK43341.1 - 0.028 14.3 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Sec34-like family CNOT1_TTP_bind PF16417.5 KKK43341.1 - 0.031 13.5 0.2 0.043 13.0 0.2 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Mating_N PF12731.7 KKK43341.1 - 0.035 14.2 0.2 0.079 13.1 0.1 1.6 1 1 1 2 2 2 0 Mating-type protein beta 1 FlaC_arch PF05377.11 KKK43341.1 - 0.038 14.4 0.5 0.075 13.4 0.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 KKK43341.1 - 0.056 11.4 0.3 0.063 11.2 0.3 1.0 1 0 0 1 1 1 0 Prominin SKA2 PF16740.5 KKK43341.1 - 0.074 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 RST PF12174.8 KKK43341.1 - 0.085 12.8 2.6 0.11 12.5 0.0 2.3 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Cep57_MT_bd PF06657.13 KKK43341.1 - 0.086 13.3 0.2 0.73 10.3 0.1 2.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SHOCT PF09851.9 KKK43341.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Short C-terminal domain CheZ PF04344.13 KKK43341.1 - 0.15 12.0 1.2 4.8 7.1 0.3 2.0 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ GP41 PF00517.17 KKK43341.1 - 0.15 11.9 2.5 0.22 11.4 2.5 1.3 1 1 0 1 1 1 0 Retroviral envelope protein TACC_C PF05010.14 KKK43341.1 - 0.23 11.2 4.4 0.37 10.5 4.4 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Trypan_glycop PF00913.19 KKK43341.1 - 0.33 10.2 2.8 0.38 10.0 2.8 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF1515 PF07439.11 KKK43341.1 - 0.78 9.8 4.6 0.2 11.7 1.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) NS3 PF17530.2 KKK43343.1 - 0.0042 16.7 1.8 0.0054 16.3 0.2 1.8 2 0 0 2 2 2 1 Non-structural protein NS3 Glyco_hydro_130 PF04041.13 KKK43344.1 - 1.1e-53 182.3 1.3 9.5e-53 179.2 1.3 1.9 1 1 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase DUF2582 PF10771.9 KKK43344.1 - 4e-12 46.1 0.0 1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix domain (DUF2582) Glyco_hydro_32N PF00251.20 KKK43344.1 - 4.7e-05 23.1 0.0 8.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KKK43344.1 - 0.00016 21.1 0.2 0.0038 16.6 0.2 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 Form-deh_trans PF09163.11 KKK43344.1 - 0.14 11.9 0.4 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Glycos_transf_1 PF00534.20 KKK43345.1 - 1.1e-14 54.3 0.2 2.4e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK43345.1 - 2.9e-10 40.7 0.0 1e-09 38.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_hydro_88 PF07470.13 KKK43345.1 - 1.7e-05 24.1 0.6 3.9e-05 22.9 0.6 1.6 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 KKK43345.1 - 0.0067 15.9 0.1 0.94 8.9 0.0 2.6 2 0 0 2 2 2 2 D-glucuronyl C5-epimerase C-terminus Glyco_trans_1_2 PF13524.6 KKK43345.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Acetyltransf_7 PF13508.7 KKK43346.1 - 8.5e-08 32.5 0.1 1.4e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK43346.1 - 6.7e-05 23.1 0.1 8.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KKK43346.1 - 9.8e-05 22.4 0.1 0.00035 20.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK43346.1 - 0.002 18.1 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK43346.1 - 0.0071 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KKK43346.1 - 0.031 14.4 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Radical_SAM PF04055.21 KKK43347.1 - 1.7e-11 44.8 0.0 2.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KKK43347.1 - 0.0018 18.4 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Succ_CoA_lig PF13607.6 KKK43349.1 - 8.6e-44 148.7 0.0 1e-42 145.2 0.0 2.6 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK43349.1 - 1.3e-15 57.9 0.0 2.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK43349.1 - 8.1e-10 39.3 0.0 3.1e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Nitroreductase PF00881.24 KKK43350.1 - 8e-21 74.8 0.0 9.7e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK43350.1 - 0.0022 17.6 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 2 Putative TM nitroreductase ACBP PF00887.19 KKK43350.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Acyl CoA binding protein DUF3368 PF11848.8 KKK43351.1 - 3e-08 33.3 0.0 8e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3368) UPF0175 PF03683.13 KKK43352.1 - 4.3e-08 32.7 0.3 5.9e-08 32.3 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) Ints3 PF10189.9 KKK43352.1 - 0.073 12.3 0.1 0.11 11.8 0.0 1.3 1 1 0 1 1 1 0 Integrator complex subunit 3 PP_kinase PF02503.17 KKK43352.1 - 0.18 11.3 2.9 0.24 11.0 1.1 1.7 1 1 1 2 2 2 0 Polyphosphate kinase middle domain FlpD PF02662.16 KKK43354.1 - 9.6e-42 141.9 2.3 3.7e-41 140.0 0.3 2.7 2 1 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit Fer4 PF00037.27 KKK43354.1 - 4.5e-17 61.1 40.4 1e-05 25.2 3.0 5.4 5 0 0 5 5 5 4 4Fe-4S binding domain Pyr_redox_2 PF07992.14 KKK43354.1 - 3.9e-12 46.0 0.0 6.5e-11 42.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_16 PF13484.6 KKK43354.1 - 7.1e-12 46.1 29.3 0.00021 22.2 7.7 4.6 4 1 1 5 5 4 3 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 KKK43354.1 - 8.2e-12 44.7 37.1 0.00047 20.1 4.0 4.8 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_7 PF12838.7 KKK43354.1 - 2.4e-11 44.0 33.4 3.3e-07 30.8 11.6 3.9 3 2 1 4 4 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK43354.1 - 5.9e-11 42.7 18.5 0.005 17.3 2.3 4.8 4 0 0 4 4 4 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43354.1 - 2.9e-10 40.1 36.4 3.2e-07 30.4 10.8 4.1 3 1 2 5 5 4 4 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43354.1 - 1.4e-09 37.9 28.3 0.00044 20.3 12.6 4.4 3 1 1 4 4 4 4 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43354.1 - 3.3e-09 36.8 32.5 4.1e-06 26.8 11.0 4.4 4 0 0 4 4 4 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43354.1 - 3e-08 33.3 39.2 0.00042 20.2 2.4 5.5 5 0 0 5 5 4 4 4Fe-4S binding domain DAO PF01266.24 KKK43354.1 - 3.1e-05 23.7 0.9 0.00012 21.8 0.6 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK43354.1 - 3.9e-05 23.8 0.0 9.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK43354.1 - 7.9e-05 22.2 0.6 0.00015 21.2 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK43354.1 - 0.00036 19.4 0.6 0.0022 16.8 0.5 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KKK43354.1 - 0.00036 19.7 0.5 0.00054 19.2 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 KKK43354.1 - 0.00069 20.0 27.5 0.061 13.8 0.4 4.8 3 1 1 4 4 4 1 4Fe-4S dicluster domain Thi4 PF01946.17 KKK43354.1 - 0.00071 18.9 0.2 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Fer4_22 PF17179.4 KKK43354.1 - 0.0079 17.0 20.3 0.71 10.8 0.2 5.3 5 0 0 5 5 5 2 4Fe-4S dicluster domain GIDA PF01134.22 KKK43354.1 - 0.0082 15.3 0.0 0.018 14.1 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KKK43354.1 - 0.014 15.9 2.3 0.14 12.7 0.1 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK43354.1 - 0.015 14.6 2.1 0.5 9.6 0.3 2.0 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KKK43354.1 - 0.038 13.3 0.3 0.08 12.2 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KKK43354.1 - 0.11 11.8 0.3 0.18 11.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Fer4_15 PF13459.6 KKK43354.1 - 1 10.2 22.6 0.58 10.9 0.4 4.7 4 0 0 4 4 4 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 KKK43354.1 - 1.6 9.4 42.6 0.067 13.7 2.6 5.0 5 0 0 5 5 4 0 4Fe-4S binding domain TPP_enzyme_C PF02775.21 KKK43355.1 - 1.3e-34 119.2 0.0 1.9e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 KKK43356.1 - 4.4e-69 232.8 0.6 5.4e-69 232.5 0.6 1.1 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KKK43356.1 - 3e-15 56.4 0.0 6.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II TPP_enzyme_N PF02776.18 KKK43356.1 - 0.005 16.5 0.1 0.0088 15.7 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transketolase_C PF02780.20 KKK43356.1 - 0.0081 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain IF-2B PF01008.17 KKK43356.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family URO-D PF01208.17 KKK43358.1 - 0.028 13.6 0.0 0.34 10.0 0.0 2.0 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Y1_Tnp PF01797.16 KKK43358.1 - 0.08 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Transposase IS200 like Amidohydro_2 PF04909.14 KKK43360.1 - 4.8e-29 102.1 0.0 5.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Cyclase PF04199.13 KKK43361.1 - 3.2e-33 114.9 0.3 3.9e-33 114.6 0.3 1.1 1 0 0 1 1 1 1 Putative cyclase Hist_deacetyl PF00850.19 KKK43363.1 - 3e-63 214.1 0.0 4.6e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Profilin PF00235.19 KKK43364.1 - 9.1e-05 22.7 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 Profilin FtsX PF02687.21 KKK43365.1 - 1.5e-05 25.4 10.8 1.5e-05 25.4 10.8 2.9 1 1 1 2 2 2 1 FtsX-like permease family OSTMP1 PF09777.9 KKK43365.1 - 5.6 6.3 5.2 0.82 9.0 0.5 1.9 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor ABC_tran PF00005.27 KKK43366.1 - 2.8e-31 108.8 0.0 4.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK43366.1 - 4.3e-05 23.1 0.1 0.00057 19.4 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK43366.1 - 4.8e-05 23.3 0.1 0.028 14.2 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKK43366.1 - 0.00031 21.2 0.0 0.00046 20.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KKK43366.1 - 0.00041 20.6 0.9 0.016 15.5 0.9 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KKK43366.1 - 0.0011 18.9 0.2 0.003 17.5 0.0 1.7 2 1 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 KKK43366.1 - 0.0026 17.7 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain T2SSE PF00437.20 KKK43366.1 - 0.0037 16.4 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KKK43366.1 - 0.0074 16.0 0.0 0.38 10.5 0.0 2.6 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.6 KKK43366.1 - 0.0082 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KKK43366.1 - 0.021 15.0 0.3 0.31 11.3 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KKK43366.1 - 0.027 14.0 0.1 0.11 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKK43366.1 - 0.036 13.8 0.1 0.09 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKK43366.1 - 0.038 14.5 0.6 0.084 13.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KKK43366.1 - 0.041 14.0 0.1 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KKK43366.1 - 0.05 14.0 0.0 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 KKK43366.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA12 PF10443.9 KKK43366.1 - 0.092 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_14 PF13173.6 KKK43366.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KKK43366.1 - 0.11 12.5 0.1 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Dynamin family DUF362 PF04015.12 KKK43367.1 - 6.2e-41 140.9 0.4 7.7e-41 140.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF362) zf-ribbon_3 PF13248.6 KKK43368.1 - 2.9e-07 29.6 1.4 4.5e-07 29.1 1.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK43368.1 - 5.8e-06 25.9 2.4 9.1e-06 25.2 2.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK43368.1 - 0.00024 21.1 0.4 0.00036 20.5 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK43368.1 - 0.0043 17.8 0.9 0.0067 17.2 0.9 1.3 1 0 0 1 1 1 1 zinc-ribbon family Phage_holin_3_3 PF16083.5 KKK43368.1 - 0.037 14.1 0.1 0.037 14.1 0.1 2.9 3 2 0 3 3 3 0 LydA holin phage, holin superfamily III zf-HYPF PF07503.12 KKK43368.1 - 0.089 12.6 0.9 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 HypF finger Rick_17kDa_Anti PF05433.15 KKK43368.1 - 0.15 11.9 0.1 0.15 11.9 0.1 3.0 3 0 0 3 3 3 0 Glycine zipper 2TM domain DUF2070 PF09843.9 KKK43368.1 - 1.4 7.1 7.6 1.5 7.0 7.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Gly-zipper_Omp PF13488.6 KKK43368.1 - 3 7.9 8.1 0.74 9.9 0.4 2.8 2 1 0 2 2 2 0 Glycine zipper DUF5453 PF17534.2 KKK43368.1 - 8.8 6.2 9.4 0.74 9.7 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5453) Phage_holin_3_7 PF05449.11 KKK43369.1 - 0.00067 19.6 4.1 0.22 11.6 0.2 2.7 2 0 0 2 2 2 2 Putative 3TM holin, Phage_holin_3 TBK1_ULD PF18396.1 KKK43370.1 - 0.006 16.5 0.6 0.73 9.8 0.2 2.5 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain SdrD_B PF17210.3 KKK43370.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 SdrD B-like domain AMP-binding PF00501.28 KKK43371.1 - 1.6e-75 254.3 0.0 1.9e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK43371.1 - 9.8e-15 55.3 0.0 2.9e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ScsC_N PF18312.1 KKK43371.1 - 0.0052 16.6 0.3 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 Copper resistance protein ScsC N-terminal domain Penicillinase_R PF03965.16 KKK43372.1 - 0.00098 19.5 0.1 0.0028 18.0 0.1 1.7 1 0 0 1 1 1 1 Penicillinase repressor Plasmid_stab_B PF10784.9 KKK43372.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Plasmid stability protein PHD_like PF12910.7 KKK43372.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.8 4 0 0 4 4 4 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Ras PF00071.22 KKK43373.1 - 6.4e-47 159.2 0.1 7.3e-47 159.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK43373.1 - 3.1e-27 95.2 0.0 4e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK43373.1 - 4.3e-15 55.6 0.0 5e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK43373.1 - 6.5e-08 32.2 0.0 6.8e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK43373.1 - 8.1e-06 25.4 0.0 8.9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KKK43373.1 - 0.00046 20.0 0.3 0.0059 16.4 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KKK43373.1 - 0.00087 19.2 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ATPase PF06745.13 KKK43373.1 - 0.0012 18.2 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 KKK43373.1 - 0.0012 18.6 0.1 0.0018 18.1 0.0 1.5 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 KKK43373.1 - 0.0018 18.3 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 KKK43373.1 - 0.002 17.7 0.0 0.19 11.2 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KKK43373.1 - 0.0024 18.2 0.1 0.0057 16.9 0.1 1.6 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 KKK43373.1 - 0.0025 17.9 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KKK43373.1 - 0.0047 16.5 0.1 0.0078 15.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KKK43373.1 - 0.0053 17.2 0.0 0.01 16.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK43373.1 - 0.0073 16.2 0.0 2 8.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Viral_helicase1 PF01443.18 KKK43373.1 - 0.008 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KKK43373.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KKK43373.1 - 0.02 15.4 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 KKK43373.1 - 0.026 14.5 0.2 0.051 13.6 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KKK43373.1 - 0.027 14.5 0.1 0.043 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK43373.1 - 0.03 14.2 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 NTPase ATP-synt_ab PF00006.25 KKK43373.1 - 0.056 13.1 0.0 0.056 13.1 0.0 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 KKK43373.1 - 0.064 13.0 0.0 2 8.1 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KKK43373.1 - 0.078 12.2 0.1 0.14 11.3 0.1 1.4 2 0 0 2 2 1 0 NB-ARC domain AAA_23 PF13476.6 KKK43373.1 - 0.081 13.4 0.6 0.17 12.4 0.6 1.8 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 KKK43373.1 - 0.083 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CsrA PF02599.16 KKK43373.1 - 0.096 12.7 0.1 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 Global regulator protein family AAA_5 PF07728.14 KKK43373.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_31 PF13847.6 KKK43373.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MobB PF03205.14 KKK43373.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KKK43373.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KKK43373.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KKK43373.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Septin PF00735.18 KKK43373.1 - 0.14 11.4 0.2 0.3 10.3 0.1 1.5 2 0 0 2 2 2 0 Septin AAA_28 PF13521.6 KKK43373.1 - 0.17 12.1 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KKK43373.1 - 0.17 11.0 0.4 5.9 5.9 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Fer4 PF00037.27 KKK43374.1 - 8.1e-05 22.3 14.5 0.00065 19.4 2.9 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK43374.1 - 0.00022 21.3 10.2 0.00054 20.1 10.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43374.1 - 0.00044 20.3 13.1 0.02 15.0 13.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43374.1 - 0.00066 19.7 10.7 0.012 15.6 3.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK43374.1 - 0.00069 20.5 14.1 0.0082 17.1 14.1 2.3 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KKK43374.1 - 0.0011 18.9 10.8 0.016 15.3 2.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK43374.1 - 0.0013 19.3 10.6 0.003 18.1 10.6 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43374.1 - 0.0025 17.9 12.8 0.042 14.0 13.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK43374.1 - 0.017 16.0 12.1 0.66 11.1 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK43374.1 - 0.36 11.4 9.8 2.6 8.7 9.9 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK43374.1 - 1.6 9.4 9.8 2.4 8.9 2.2 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK43374.1 - 1.7 8.9 10.8 7.8 6.7 2.4 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK43374.1 - 4 7.9 12.1 7.7 7.1 3.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK43374.1 - 6.1 7.5 9.6 5.4 7.6 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Lin0512_fam PF09585.10 KKK43375.1 - 1.4e-38 131.4 0.2 1.6e-38 131.3 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) Dehalogenase PF13486.6 KKK43376.1 - 7.4e-24 84.6 0.0 7.2e-23 81.4 0.0 2.1 1 1 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 KKK43376.1 - 2.5e-08 34.7 9.2 6.4e-08 33.4 9.2 1.8 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK43376.1 - 1.6e-06 28.6 6.6 3.2e-06 27.6 6.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK43376.1 - 0.0019 17.9 11.1 0.02 14.7 1.6 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK43376.1 - 0.017 15.2 10.6 0.056 13.6 10.8 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43376.1 - 0.021 15.0 10.6 0.54 10.5 3.0 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43376.1 - 0.028 14.5 8.3 1 9.5 0.6 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK43376.1 - 0.053 14.0 1.6 0.053 14.0 1.6 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK43376.1 - 0.21 11.8 8.8 0.69 10.1 0.5 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK43376.1 - 4.5 7.9 10.8 23 5.6 10.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain AMP-binding PF00501.28 KKK43377.1 - 8.3e-55 186.1 0.0 1e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK43377.1 - 0.01 16.8 0.0 0.03 15.3 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Autoind_bind PF03472.15 KKK43377.1 - 0.11 12.0 0.0 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 Autoinducer binding domain tRNA-synt_1d PF00750.19 KKK43379.1 - 3.5e-45 154.5 1.4 5e-45 153.9 1.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KKK43379.1 - 1.2e-30 106.1 0.2 5.5e-30 104.0 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KKK43379.1 - 2.8e-10 40.6 0.1 7.5e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 KKK43379.1 - 0.18 10.5 1.9 2.3 6.9 0.0 3.1 4 0 0 4 4 4 0 tRNA synthetases class I (M) Arginase PF00491.21 KKK43380.1 - 2.4e-65 220.8 0.0 2.8e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family DS PF01916.17 KKK43381.1 - 6.4e-87 291.5 0.0 7.8e-87 291.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase SepSecS PF05889.13 KKK43381.1 - 0.19 10.4 0.0 0.38 9.4 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF3567 PF12091.8 KKK43382.1 - 0.0041 17.2 0.1 0.01 15.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3567) ERAP1_C PF11838.8 KKK43382.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 1 0 1 1 1 0 ERAP1-like C-terminal domain Peptidase_M29 PF02073.15 KKK43383.1 - 1.7e-16 60.0 0.0 2.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) UPF0182 PF03699.13 KKK43392.1 - 1e-07 30.5 2.4 1.9e-07 29.7 2.4 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0182) Fer4_7 PF12838.7 KKK43393.1 - 0.006 17.1 3.3 0.12 12.9 2.8 2.5 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43393.1 - 0.013 15.5 10.9 0.02 15.0 2.2 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 KKK43393.1 - 0.22 12.5 7.0 21 6.1 0.0 2.9 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK43393.1 - 1.4 9.1 10.4 3.5 7.9 4.5 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43393.1 - 5 7.3 10.2 23 5.2 6.0 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43393.1 - 5.5 7.2 10.8 0.88 9.8 0.6 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain NMO PF03060.15 KKK43394.1 - 2.2e-24 86.5 0.0 2.4e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KKK43394.1 - 0.00012 21.2 0.2 0.00019 20.6 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK43394.1 - 0.046 12.7 0.3 0.066 12.2 0.3 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Cupin_2 PF07883.11 KKK43397.1 - 2e-11 43.4 0.0 2.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KKK43397.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain CENP-C_C PF11699.8 KKK43397.1 - 0.00055 20.1 0.0 0.00073 19.7 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like DMSP_lyase PF16867.5 KKK43397.1 - 0.055 13.1 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Fe-ADH PF00465.19 KKK43398.1 - 3.8e-72 243.1 0.0 4.4e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK43398.1 - 3.7e-11 43.2 0.3 4.4e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Zn_Tnp_IS1595 PF12760.7 KKK43400.1 - 0.082 12.9 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-IS66 PF13005.7 KKK43400.1 - 0.15 12.5 3.6 2.2 8.7 3.6 2.4 1 1 0 1 1 1 0 zinc-finger binding domain of transposase IS66 ADK_lid PF05191.14 KKK43400.1 - 0.27 11.3 2.7 1.4 9.0 2.7 2.1 1 1 0 1 1 1 0 Adenylate kinase, active site lid DSPc PF00782.20 KKK43401.1 - 5.2e-18 65.1 0.0 5.8e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 KKK43401.1 - 2.8e-05 23.9 0.0 3.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 KKK43401.1 - 5.6e-05 22.8 0.0 8.8e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KKK43401.1 - 0.00061 19.9 0.0 0.00087 19.4 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 KKK43401.1 - 0.0082 16.4 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 KKK43401.1 - 0.19 11.6 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Acyl-CoA_dh_1 PF00441.24 KKK43402.1 - 8e-34 117.0 0.1 1.2e-33 116.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK43402.1 - 1.5e-20 73.2 0.0 2.8e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK43402.1 - 8.7e-14 51.9 0.0 2.1e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK43402.1 - 7.8e-13 49.1 0.0 1.5e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Methyltransf_31 PF13847.6 KKK43403.1 - 1.4e-15 57.4 0.0 2.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK43403.1 - 2.2e-14 53.9 0.0 5.8e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK43403.1 - 4e-14 52.8 0.0 6.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK43403.1 - 7.2e-14 52.3 0.0 1.5e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK43403.1 - 7.6e-14 52.1 0.0 2.2e-13 50.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KKK43403.1 - 2.1e-08 33.7 0.0 3.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KKK43403.1 - 1.6e-06 27.6 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 KKK43403.1 - 2.9e-05 25.1 0.0 5.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK43403.1 - 4.4e-05 23.1 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KKK43403.1 - 8.8e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Spermine_synth PF01564.17 KKK43403.1 - 0.00064 19.2 0.2 0.0014 18.1 0.2 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain CheR PF01739.18 KKK43403.1 - 0.0011 18.5 0.1 0.31 10.5 0.1 2.6 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Pox_MCEL PF03291.16 KKK43403.1 - 0.0015 17.8 0.2 0.004 16.3 0.1 1.7 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_18 PF12847.7 KKK43403.1 - 0.0085 16.0 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KKK43403.1 - 0.0085 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 KKK43403.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.13 KKK43403.1 - 0.12 12.3 0.0 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltransf_5 PF01795.19 KKK43403.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Zincin_1 PF06262.11 KKK43403.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase PCMT PF01135.19 KKK43403.1 - 0.18 11.6 0.0 0.48 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NRD1_2 PF01995.16 KKK43404.1 - 0.067 12.5 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 DUF1667 PF07892.11 KKK43405.1 - 5.3e-31 106.5 0.1 7.2e-31 106.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1667) SIN1 PF05422.12 KKK43405.1 - 0.22 12.1 0.0 0.31 11.6 0.0 1.2 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) TerC PF03741.16 KKK43410.1 - 0.048 13.3 3.4 0.07 12.8 3.4 1.3 1 1 0 1 1 1 0 Integral membrane protein TerC family DUF373 PF04123.13 KKK43410.1 - 0.092 12.2 3.5 0.12 11.9 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4131 PF13567.6 KKK43410.1 - 3 7.5 6.7 1.2 8.7 3.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Saf_2TM PF18303.1 KKK43411.1 - 0.084 12.5 0.9 0.11 12.1 0.9 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Flp1_like PF16982.5 KKK43411.1 - 0.21 11.0 4.4 0.43 10.0 0.4 2.2 2 0 0 2 2 2 0 Putative Flagellin, Flp1-like, domain DUF1206 PF06724.11 KKK43411.1 - 0.23 11.6 4.9 0.28 11.3 0.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF4902 PF16245.5 KKK43416.1 - 0.074 12.9 0.2 0.088 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4902) DUF2970 PF11174.8 KKK43418.1 - 0.082 12.8 0.2 0.082 12.8 0.2 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2970) PEMT PF04191.13 KKK43419.1 - 1.5e-07 31.7 2.1 1.5e-07 31.7 2.1 1.7 1 1 1 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KKK43419.1 - 7e-05 22.5 1.9 0.00022 20.8 1.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KKK43419.1 - 0.0016 18.8 2.1 0.0016 18.8 2.1 1.8 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KKK43419.1 - 0.43 10.5 5.4 2.8 7.9 5.4 2.1 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Sigma_reg_N PF13800.6 KKK43419.1 - 7.5 6.9 19.7 3.9 7.8 1.8 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal PDDEXK_9 PF08011.11 KKK43421.1 - 0.0021 17.9 0.1 0.0025 17.7 0.1 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily bPH_3 PF14470.6 KKK43422.1 - 0.0037 17.6 0.1 0.008 16.5 0.0 1.5 2 0 0 2 2 2 1 Bacterial PH domain DUF2207 PF09972.9 KKK43422.1 - 0.041 12.6 1.1 0.049 12.4 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) 2TM PF13239.6 KKK43422.1 - 0.16 12.3 2.9 0.29 11.5 2.9 1.4 1 0 0 1 1 1 0 2TM domain Oleosin PF01277.17 KKK43422.1 - 0.38 10.5 4.3 0.53 10.1 4.3 1.2 1 0 0 1 1 1 0 Oleosin Phage_holin_3_6 PF07332.11 KKK43422.1 - 2.9 8.0 4.9 4.3 7.4 4.9 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III GT87 PF09594.10 KKK43424.1 - 3.6e-11 43.2 8.7 6.1e-11 42.5 8.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 87 EpsG PF14897.6 KKK43424.1 - 0.0015 17.9 35.9 0.0015 17.9 35.9 2.2 1 1 1 2 2 2 1 EpsG family Peptidase_U32 PF01136.19 KKK43425.1 - 2.7e-07 30.0 0.0 2.8e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family U32 TssN PF17555.2 KKK43426.1 - 0.018 14.4 10.9 0.023 14.1 10.9 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN GPI2 PF06432.11 KKK43426.1 - 0.44 9.9 7.6 0.2 11.1 5.7 1.4 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Viral_Beta_CD PF04530.12 KKK43426.1 - 0.65 10.3 3.5 17 5.7 0.2 2.1 1 1 1 2 2 2 0 Viral Beta C/D like family FA_desaturase PF00487.24 KKK43426.1 - 6 6.6 10.8 12 5.6 10.9 1.4 1 1 0 1 1 1 0 Fatty acid desaturase DNA_RNApol_7kD PF03604.13 KKK43431.1 - 4.5e-05 23.0 0.9 7.7e-05 22.3 0.9 1.4 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 KKK43431.1 - 0.028 14.5 0.4 0.065 13.4 0.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KKK43431.1 - 0.047 13.4 5.3 0.64 9.8 5.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain DUF4776 PF16003.5 KKK43431.1 - 0.049 12.6 0.1 0.063 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Prok-RING_1 PF14446.6 KKK43431.1 - 0.05 13.5 0.6 0.076 13.0 0.6 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 HypA PF01155.19 KKK43431.1 - 0.054 13.5 0.3 0.096 12.7 0.2 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KKK43431.1 - 0.078 12.6 1.7 0.23 11.1 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 KKK43431.1 - 0.12 11.9 1.8 2.5 7.7 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_7 PF02591.15 KKK43431.1 - 0.13 12.5 0.8 0.25 11.5 0.3 1.8 1 1 0 1 1 1 0 C4-type zinc ribbon domain zf-DNL PF05180.12 KKK43431.1 - 0.15 12.0 0.2 11 6.1 0.0 3.0 3 0 0 3 3 3 0 DNL zinc finger zf-ribbon_3 PF13248.6 KKK43431.1 - 0.48 9.9 6.7 0.46 10.0 0.9 2.1 1 1 0 1 1 1 0 zinc-ribbon domain tRNA-synt_1c PF00749.21 KKK43432.1 - 2.3e-59 200.9 0.0 3.9e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KKK43432.1 - 3.9e-24 85.5 0.2 2e-23 83.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain HAD_2 PF13419.6 KKK43433.1 - 6.4e-28 98.0 2.9 1.7e-27 96.7 2.9 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK43433.1 - 2.8e-12 47.4 0.0 3.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK43433.1 - 2.6e-08 33.8 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like LepB_N PF18640.1 KKK43434.1 - 0.0025 17.5 3.8 0.0029 17.3 2.9 1.6 1 1 0 1 1 1 1 LepB N-terminal domain FliG_M PF14841.6 KKK43434.1 - 0.039 14.2 0.2 12 6.2 0.0 2.7 2 0 0 2 2 2 0 FliG middle domain NuiA PF07924.11 KKK43434.1 - 0.12 12.8 8.4 0.086 13.2 0.9 2.2 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein Vasculin PF15337.6 KKK43434.1 - 1.2 10.1 6.2 0.48 11.3 3.2 2.0 1 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 NTP_transferase PF00483.23 KKK43435.1 - 1e-24 87.5 0.0 1.4e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KKK43435.1 - 6e-06 25.8 7.7 2.3e-05 23.9 1.5 4.0 3 2 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KKK43435.1 - 0.00018 20.6 0.2 0.0023 16.9 0.2 2.2 2 0 0 2 2 2 1 L-fucokinase Hexapep_2 PF14602.6 KKK43435.1 - 0.0028 17.4 2.0 0.0077 16.0 0.5 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 KKK43435.1 - 0.0037 17.6 0.0 0.0049 17.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KKK43435.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 KKK43435.1 - 0.047 11.8 0.3 0.091 10.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Amidase PF01425.21 KKK43436.1 - 7.1e-115 384.5 0.0 3.1e-114 382.4 0.0 1.7 1 1 0 1 1 1 1 Amidase DinI PF06183.13 KKK43436.1 - 0.048 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 DinI-like family ABC_tran PF00005.27 KKK43437.1 - 1.3e-34 119.6 0.1 2.4e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKK43437.1 - 3.7e-32 112.1 11.9 3.7e-32 112.1 11.9 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF87 PF01935.17 KKK43437.1 - 0.00047 20.3 0.4 0.0015 18.7 0.2 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain SMC_N PF02463.19 KKK43437.1 - 0.0011 18.5 2.8 0.16 11.3 0.1 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF815 PF05673.13 KKK43437.1 - 0.0045 16.2 0.1 0.0075 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KKK43437.1 - 0.0081 16.6 1.0 0.039 14.3 0.4 2.4 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KKK43437.1 - 0.01 15.6 0.1 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KKK43437.1 - 0.017 15.5 0.4 0.55 10.7 0.4 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KKK43437.1 - 0.02 14.7 0.1 0.02 14.7 0.1 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKK43437.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 KKK43437.1 - 0.031 14.8 0.0 0.082 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 KKK43437.1 - 0.071 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Zeta_toxin PF06414.12 KKK43437.1 - 0.082 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 KKK43437.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KKK43437.1 - 0.15 11.1 0.1 0.28 10.2 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 KKK43437.1 - 0.2 12.1 3.4 0.65 10.5 3.4 2.2 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 KKK43438.1 - 5.3e-38 131.2 25.9 6.7e-38 130.9 25.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK43438.1 - 3e-33 115.2 0.0 5.4e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK43438.1 - 4e-06 26.4 0.0 0.0012 18.3 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KKK43438.1 - 0.0012 18.7 0.6 1.1 9.0 0.0 3.1 1 1 2 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KKK43438.1 - 0.0017 18.3 0.1 0.0055 16.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase DUF2208 PF09973.9 KKK43438.1 - 0.0029 17.3 2.8 0.0029 17.3 2.8 3.4 3 1 0 3 3 2 1 Predicted membrane protein (DUF2208) CitMHS PF03600.16 KKK43438.1 - 0.0035 16.6 6.3 0.0068 15.6 6.3 1.4 1 0 0 1 1 1 1 Citrate transporter DUF87 PF01935.17 KKK43438.1 - 0.0059 16.7 0.1 0.016 15.3 0.1 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain DEAD PF00270.29 KKK43438.1 - 0.0094 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 KKK43438.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KKK43438.1 - 0.039 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KKK43438.1 - 0.061 12.6 0.2 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin SVS_QK PF10578.9 KKK43438.1 - 0.076 13.6 0.7 0.3 11.8 0.7 2.1 1 0 0 1 1 1 0 Seminal vesicle protein repeat GTP_EFTU PF00009.27 KKK43438.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KKK43438.1 - 0.12 12.8 0.1 0.26 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KKK43438.1 - 0.12 12.7 0.1 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KKK43438.1 - 0.69 10.4 3.4 0.27 11.7 0.3 1.9 2 1 0 2 2 2 0 AAA domain DUF2207 PF09972.9 KKK43438.1 - 2.9 6.6 14.9 0.023 13.5 2.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) HIT PF01230.23 KKK43439.1 - 1.8e-21 76.7 1.8 2.3e-21 76.3 1.8 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KKK43439.1 - 5e-12 46.3 1.4 6.7e-12 45.9 1.4 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KKK43439.1 - 0.00054 19.8 1.3 0.00078 19.3 1.3 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF4293 PF14126.6 KKK43440.1 - 2.5 8.3 7.9 1.1 9.6 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF872 PF05915.12 KKK43440.1 - 4.2 7.6 8.2 0.48 10.6 1.6 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Succ_CoA_lig PF13607.6 KKK43442.1 - 2.9e-40 137.3 0.0 5.4e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain KIP1 PF07765.12 KKK43442.1 - 0.028 14.5 0.5 0.92 9.7 0.1 2.4 2 0 0 2 2 2 0 KIP1-like protein zf-ribbon_3 PF13248.6 KKK43443.1 - 3.6e-07 29.4 2.9 5.3e-07 28.8 2.9 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK43443.1 - 1.6e-05 24.8 0.5 2e-05 24.5 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK43443.1 - 5.1e-05 22.8 13.6 0.00043 19.9 6.4 2.1 1 1 1 2 2 2 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK43443.1 - 8.9e-05 23.2 0.3 9.7e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 zinc-ribbon family Nudix_N_2 PF14803.6 KKK43443.1 - 0.009 15.9 3.7 1 9.3 0.3 2.3 2 0 0 2 2 2 2 Nudix N-terminal TF_Zn_Ribbon PF08271.12 KKK43443.1 - 0.02 14.4 2.6 1.5 8.4 0.4 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4187 PF13821.6 KKK43443.1 - 0.024 14.4 0.4 0.043 13.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zinc_ribbon_11 PF11682.8 KKK43443.1 - 0.086 12.8 0.7 0.14 12.2 0.8 1.4 1 1 0 1 1 1 0 Probable zinc-ribbon HypA PF01155.19 KKK43443.1 - 0.12 12.4 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 KKK43443.1 - 0.13 11.9 2.8 0.97 9.2 0.6 2.3 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF1272 PF06906.11 KKK43443.1 - 0.14 12.3 2.0 0.2 11.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) NOB1_Zn_bind PF08772.11 KKK43443.1 - 0.15 12.2 6.1 3.4 7.9 0.9 2.9 1 1 2 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like A2L_zn_ribbon PF08792.10 KKK43443.1 - 0.4 10.4 9.5 0.52 10.1 6.3 2.5 2 1 0 2 2 2 0 A2L zinc ribbon domain zf-RRN7 PF11781.8 KKK43443.1 - 0.55 10.0 7.8 4.2 7.1 0.5 2.4 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PknG_rubred PF16919.5 KKK43443.1 - 0.59 10.3 2.3 2.8 8.1 1.4 2.3 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain NTP_transferase PF00483.23 KKK43444.1 - 2e-28 99.7 0.0 2.3e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KKK43444.1 - 1.4e-10 41.7 0.0 1.8e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 KKK43444.1 - 0.032 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.19 KKK43444.1 - 0.087 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TrmB PF01978.19 KKK43445.1 - 0.00084 19.2 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Pox_C7_F8A PF03287.14 KKK43445.1 - 0.031 14.3 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 Poxvirus C7/F8A protein HTH_24 PF13412.6 KKK43445.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 KKK43445.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain CheR PF01739.18 KKK43446.1 - 6.3e-46 156.3 0.0 2e-45 154.7 0.0 1.9 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheD PF03975.13 KKK43446.1 - 3.7e-14 52.7 0.0 1.5e-13 50.8 0.0 2.1 3 0 0 3 3 3 1 CheD chemotactic sensory transduction CheR_N PF03705.15 KKK43446.1 - 3.9e-06 26.5 3.6 3.9e-06 26.5 3.6 2.5 3 0 0 3 3 3 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 KKK43446.1 - 3.7e-05 24.4 0.7 0.0039 17.9 0.1 3.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK43446.1 - 0.00035 20.4 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK43446.1 - 0.00051 20.7 0.1 0.0079 16.9 0.0 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK43446.1 - 0.00061 20.4 0.0 0.0073 16.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain DUF2313 PF10076.9 KKK43446.1 - 0.0027 17.6 1.5 0.0064 16.4 1.5 1.6 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2313) TPMT PF05724.11 KKK43446.1 - 0.037 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltr_RsmF_N PF17125.5 KKK43446.1 - 6.3 7.4 8.0 3.8 8.1 1.7 3.5 4 0 0 4 4 4 0 N-terminal domain of 16S rRNA methyltransferase RsmF GHMP_kinases_N PF00288.26 KKK43447.1 - 6.7e-13 48.7 0.1 1.6e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK43447.1 - 1.2e-11 44.8 0.3 3.1e-11 43.5 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KKK43447.1 - 0.019 14.5 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Galactokinase galactose-binding signature BppU_N PF10651.9 KKK43447.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 BppU N-terminal domain CDP-OH_P_transf PF01066.21 KKK43449.1 - 1.6e-12 48.0 2.6 1.6e-12 48.0 2.6 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CTP-dep_RFKase PF01982.16 KKK43450.1 - 1.3e-34 118.9 0.1 2.4e-34 118.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF120 MarR PF01047.22 KKK43450.1 - 0.00028 20.7 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KKK43450.1 - 0.0006 19.3 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 KKK43450.1 - 0.0022 17.9 0.2 0.0051 16.8 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 KKK43450.1 - 0.003 17.4 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KKK43450.1 - 0.0087 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_DeoR PF08220.12 KKK43450.1 - 0.019 14.7 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 KKK43450.1 - 0.032 14.3 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_1 PF00126.27 KKK43450.1 - 0.036 14.0 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF4364 PF14277.6 KKK43450.1 - 0.041 13.6 1.5 0.074 12.8 0.1 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4364) HTH_AsnC-type PF13404.6 KKK43450.1 - 0.079 12.8 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PhdYeFM_antitox PF02604.19 KKK43450.1 - 0.082 12.7 0.3 12 5.7 0.1 2.7 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system HTH_34 PF13601.6 KKK43450.1 - 0.082 13.1 0.2 0.19 12.0 0.2 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain CTP_transf_like PF01467.26 KKK43451.1 - 3.4e-13 50.0 0.1 4e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 KKK43451.1 - 0.015 15.2 0.1 0.05 13.5 0.0 1.9 1 1 0 2 2 2 0 FAD synthetase Nitrophorin PF02087.15 KKK43451.1 - 0.018 15.1 1.2 1.9 8.5 0.6 2.2 2 0 0 2 2 2 0 Nitrophorin Translin PF01997.16 KKK43452.1 - 1.6e-10 41.4 0.3 2e-09 37.8 0.3 2.0 1 1 0 1 1 1 1 Translin family Ter PF05472.11 KKK43452.1 - 0.084 11.9 0.1 0.18 10.8 0.1 1.5 2 0 0 2 2 2 0 DNA replication terminus site-binding protein (Ter protein) Flagellin_C PF00700.21 KKK43452.1 - 0.096 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF4041 PF13250.6 KKK43452.1 - 0.33 10.9 2.6 0.88 9.5 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) tRNA-Thr_ED PF08915.11 KKK43453.1 - 6.1e-25 87.9 0.7 2.1e-19 69.9 0.0 2.7 3 0 0 3 3 3 2 Archaea-specific editing domain of threonyl-tRNA synthetase HGTP_anticodon PF03129.20 KKK43453.1 - 8.7e-18 64.3 0.1 4.5e-16 58.8 0.1 3.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKK43453.1 - 8.4e-12 45.4 0.2 4.2e-11 43.1 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) IKBKB_SDD PF18397.1 KKK43453.1 - 0.011 15.0 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain YfdX PF10938.8 KKK43453.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 YfdX protein HAD_2 PF13419.6 KKK43454.1 - 2.7e-12 47.1 0.4 4.1e-12 46.5 0.4 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK43454.1 - 1.1e-07 32.3 0.0 8.2e-06 26.2 0.0 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK43454.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.8 KKK43454.1 - 0.0044 16.5 0.3 0.027 13.9 0.0 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF2608) PAZ_siRNAbind PF12212.8 KKK43454.1 - 0.012 15.4 0.4 0.021 14.6 0.4 1.3 1 0 0 1 1 1 0 PAZ domain Flavokinase PF01687.17 KKK43454.1 - 0.04 14.2 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Riboflavin kinase Ras PF00071.22 KKK43455.1 - 2e-19 69.8 0.0 2.2e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KKK43455.1 - 0.00054 19.9 0.1 0.00067 19.6 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KKK43455.1 - 0.0017 18.3 0.0 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KKK43455.1 - 0.02 14.4 0.1 0.024 14.2 0.1 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 KKK43455.1 - 0.052 13.8 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KKK43455.1 - 0.067 12.7 0.1 0.11 12.0 0.1 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.22 KKK43456.1 - 1.9e-14 53.6 0.0 2.2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK43456.1 - 5.8e-11 42.6 0.0 6.7e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KKK43456.1 - 0.014 15.2 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KKK43456.1 - 0.034 14.1 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KKK43456.1 - 0.035 14.5 0.0 0.035 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KKK43456.1 - 0.037 13.2 0.1 0.044 13.0 0.1 1.3 1 1 0 1 1 1 0 NB-ARC domain Arf PF00025.21 KKK43456.1 - 0.067 12.6 0.0 0.074 12.5 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_7 PF12775.7 KKK43456.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KKK43456.1 - 0.16 12.2 0.1 0.25 11.6 0.1 1.2 1 1 0 1 1 1 0 AAA domain DUF3640 PF12342.8 KKK43456.1 - 0.3 10.9 1.4 11 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) DUF1624 PF07786.12 KKK43457.1 - 5.7e-12 45.7 17.0 5.7e-11 42.4 15.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1624) DUF997 PF06196.12 KKK43457.1 - 1.8 8.7 0.0 1.8 8.7 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF997) GT87 PF09594.10 KKK43458.1 - 1e-16 61.4 4.1 1e-16 61.4 4.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 87 DUF418 PF04235.12 KKK43459.1 - 0.0027 17.6 5.1 0.0027 17.6 5.1 3.5 2 1 0 4 4 4 1 Protein of unknown function (DUF418) Acyl_transf_3 PF01757.22 KKK43459.1 - 0.012 14.6 49.9 0.11 11.5 49.9 2.4 1 1 0 1 1 1 0 Acyltransferase family WGR PF05406.15 KKK43459.1 - 0.87 9.7 2.9 6 7.0 0.4 2.3 2 0 0 2 2 2 0 WGR domain DUF2304 PF10066.9 KKK43460.1 - 0.75 10.0 14.9 0.039 14.2 8.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) MerC PF03203.14 KKK43460.1 - 0.9 10.0 5.6 12 6.4 5.9 2.2 1 1 0 1 1 1 0 MerC mercury resistance protein Herpes_LMP1 PF05297.11 KKK43460.1 - 2.2 7.4 13.6 2.4 7.2 13.6 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Herpes_pp38 PF04846.13 KKK43461.1 - 0.022 14.7 0.6 0.059 13.3 0.2 1.9 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein VPS9 PF02204.18 KKK43461.1 - 2.1 8.6 7.3 0.13 12.5 0.9 2.3 2 1 1 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain ATP-grasp_3 PF02655.14 KKK43462.1 - 4.4e-30 104.9 0.1 8.2e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KKK43462.1 - 9.7e-09 35.1 0.1 1.8e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus preATP-grasp_3 PF18301.1 KKK43462.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 pre ATP-grasp 3 domain ATP-grasp_4 PF13535.6 KKK43462.1 - 4.3e-08 32.9 0.2 1.2e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 ATP-grasp domain TTL PF03133.15 KKK43462.1 - 7.6e-05 22.0 1.0 0.035 13.3 0.1 2.6 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KKK43462.1 - 0.0026 17.1 0.1 0.18 11.0 0.0 2.4 2 0 0 2 2 2 1 YheC/D like ATP-grasp CPSase_L_D2 PF02786.17 KKK43462.1 - 0.023 14.2 0.0 0.77 9.2 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.16 KKK43462.1 - 0.049 13.0 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Duffy_binding PF05424.11 KKK43463.1 - 0.016 15.2 1.8 0.022 14.8 0.2 2.1 2 0 0 2 2 2 0 Duffy binding domain DUF5375 PF17345.2 KKK43463.1 - 0.055 13.3 0.2 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5375) Ldh_1_C PF02866.18 KKK43463.1 - 0.26 11.2 1.8 0.43 10.5 0.1 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain NifU_N PF01592.16 KKK43465.1 - 2.9e-18 66.2 0.0 4.6e-18 65.6 0.0 1.3 1 1 0 1 1 1 1 NifU-like N terminal domain Hydrolase_4 PF12146.8 KKK43466.1 - 9.8e-13 47.9 0.0 1.8e-12 47.0 0.0 1.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KKK43466.1 - 1.7e-08 34.2 0.0 1.5e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KKK43466.1 - 2.2e-06 28.5 0.0 2e-05 25.3 0.0 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK43466.1 - 9.2e-06 25.5 0.1 3.7e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KKK43466.1 - 0.00015 20.5 0.1 0.016 13.9 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 KKK43466.1 - 0.0039 16.8 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KKK43466.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KKK43466.1 - 0.086 12.8 0.1 1.3 8.9 0.0 2.1 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pribosyltran_N PF13793.6 KKK43467.1 - 1.5e-24 86.2 0.1 5.1e-22 78.0 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KKK43467.1 - 4.8e-13 48.9 2.3 9.9e-13 47.9 1.6 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 KKK43467.1 - 3.4e-09 37.0 1.3 3.4e-09 37.0 1.3 2.6 2 2 1 3 3 3 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 KKK43467.1 - 0.0005 19.6 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RNase_Zc3h12a PF11977.8 KKK43467.1 - 0.0055 16.5 0.5 0.37 10.6 0.1 2.2 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain Macro PF01661.21 KKK43467.1 - 0.054 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Macro domain PRTase_2 PF15609.6 KKK43467.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase ADH_zinc_N PF00107.26 KKK43467.1 - 9.9 6.2 7.3 1.8 8.5 0.5 2.8 3 1 1 4 4 4 0 Zinc-binding dehydrogenase AAA_17 PF13207.6 KKK43468.1 - 9.4e-12 45.5 0.4 1.6e-11 44.7 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK43468.1 - 2.9e-09 37.5 0.3 4.4e-09 37.0 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK43468.1 - 3.5e-07 30.5 0.0 5.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 KKK43468.1 - 0.0014 18.8 0.1 0.0018 18.4 0.1 1.4 1 1 0 1 1 1 1 Adenylate kinase ABC_tran PF00005.27 KKK43468.1 - 0.0017 18.9 0.1 0.0023 18.5 0.1 1.4 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 KKK43468.1 - 0.0027 18.0 0.4 0.0091 16.3 0.3 2.1 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 KKK43468.1 - 0.0053 16.4 1.4 0.3 10.7 0.2 2.1 1 1 1 2 2 2 1 Dephospho-CoA kinase AAA_21 PF13304.6 KKK43468.1 - 0.0075 16.1 1.5 0.013 15.3 1.5 1.4 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Viral_helicase1 PF01443.18 KKK43468.1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KKK43468.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KKK43468.1 - 0.014 14.4 1.0 0.083 11.9 0.1 2.1 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_2 PF03668.15 KKK43468.1 - 0.02 14.2 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family 5_3_exonuc PF01367.20 KKK43468.1 - 0.02 15.5 1.4 0.16 12.6 0.1 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold KTI12 PF08433.10 KKK43468.1 - 0.021 14.3 0.6 0.046 13.2 0.0 2.0 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 KKK43468.1 - 0.029 14.6 0.1 0.071 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KKK43468.1 - 0.042 13.1 0.6 0.28 10.5 0.1 2.1 1 1 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 KKK43468.1 - 0.048 13.7 0.5 0.079 13.1 0.5 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KKK43468.1 - 0.054 13.2 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 KKK43468.1 - 0.057 13.3 1.7 0.074 12.9 1.7 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_30 PF13604.6 KKK43468.1 - 0.062 13.0 0.0 0.099 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KKK43468.1 - 0.18 12.2 1.0 0.46 10.9 1.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KKK43468.1 - 0.98 9.9 13.3 40 4.6 13.3 2.1 1 1 0 1 1 1 0 AAA domain JAB PF01398.21 KKK43469.1 - 3.7e-11 43.0 0.0 1.2e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KKK43469.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KKK43469.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) DUF4342 PF14242.6 KKK43469.1 - 0.19 11.8 1.8 0.5 10.4 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Alba PF01918.21 KKK43470.1 - 1.2e-08 34.7 0.1 1.2e-08 34.7 0.1 1.6 2 0 0 2 2 2 1 Alba zf-SNAP50_C PF12251.8 KKK43471.1 - 0.0042 16.8 1.5 0.0049 16.6 1.5 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal SNARE_assoc PF09335.11 KKK43472.1 - 1.1e-09 38.7 0.2 1.1e-09 38.7 0.2 2.8 2 2 1 3 3 3 1 SNARE associated Golgi protein Jagunal PF07086.12 KKK43472.1 - 0.6 10.2 11.3 3.4 7.7 4.6 2.4 2 1 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis LapA_dom PF06305.11 KKK43472.1 - 4.6 7.1 0.0 4.6 7.1 0.0 3.4 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain Cyclophil_like PF04126.13 KKK43473.1 - 0.00021 21.1 0.0 0.00038 20.3 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 KKK43473.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin-like family DUF871 PF05913.11 KKK43473.1 - 0.021 14.0 0.1 0.026 13.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) NTP_transf_3 PF12804.7 KKK43474.1 - 6e-11 43.0 0.0 6.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KKK43474.1 - 2.6e-08 33.7 0.0 3.6e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 KKK43474.1 - 0.0013 18.7 2.0 0.036 14.0 0.1 2.2 2 0 0 2 2 2 1 Cytidylyltransferase Importin_rep_5 PF18816.1 KKK43474.1 - 0.043 14.1 1.9 0.13 12.6 0.4 2.4 2 0 0 2 2 2 0 Importin repeat IspD PF01128.19 KKK43474.1 - 0.099 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase RNA_pol_Rpb5_N PF03871.14 KKK43474.1 - 0.48 11.0 3.7 18 6.0 0.1 2.8 2 1 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain HNH PF01844.23 KKK43475.1 - 0.0036 17.4 2.3 0.0036 17.4 2.3 5.6 7 0 0 7 7 7 2 HNH endonuclease HNH_2 PF13391.6 KKK43475.1 - 0.012 15.7 1.0 0.43 10.7 0.1 2.6 2 0 0 2 2 2 0 HNH endonuclease Cytochrome_C7 PF14522.6 KKK43475.1 - 9.1 6.4 21.8 2e+02 2.0 2.9 4.1 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Peptidase_M24 PF00557.24 KKK43476.1 - 3.7e-29 101.9 0.0 3.9e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Phage_connect_1 PF05135.13 KKK43476.1 - 0.087 13.3 1.2 1 9.9 0.1 2.7 3 1 0 3 3 3 0 Phage gp6-like head-tail connector protein tRNA-synt_2 PF00152.20 KKK43477.1 - 1e-75 254.8 0.2 1.2e-75 254.5 0.2 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KKK43477.1 - 1.2e-07 31.7 0.6 3.8e-07 30.0 0.7 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KKK43477.1 - 0.00036 20.1 0.2 0.29 10.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) N6_N4_Mtase PF01555.18 KKK43478.1 - 9.7e-49 166.1 1.3 9.7e-49 166.1 1.3 2.0 2 1 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.15 KKK43478.1 - 0.062 12.9 0.0 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein 95 TruD PF01142.18 KKK43479.1 - 6e-107 358.0 0.1 6.9e-107 357.8 0.1 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) PTH2 PF01981.16 KKK43480.1 - 9.1e-36 122.7 0.5 1e-35 122.6 0.5 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Peptidase_M15_4 PF13539.6 KKK43480.1 - 0.0084 16.6 0.1 0.012 16.1 0.1 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase NOP5NT PF08156.13 KKK43480.1 - 0.034 14.5 1.0 0.055 13.9 1.0 1.5 1 1 0 1 1 1 0 NOP5NT (NUC127) domain DUF3387 PF11867.8 KKK43481.1 - 0.011 15.1 3.3 0.072 12.5 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3387) Mid1 PF12929.7 KKK43482.1 - 0.092 11.9 3.3 0.13 11.5 3.3 1.1 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component Ribosomal_L38e PF01781.18 KKK43483.1 - 5.1e-07 29.7 0.3 6.5e-07 29.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Ribosomal_L40e PF01020.17 KKK43484.1 - 2.9e-06 27.1 6.7 3.5e-06 26.8 6.7 1.1 1 0 0 1 1 1 1 Ribosomal L40e family DUF35_N PF12172.8 KKK43484.1 - 0.0025 17.7 0.6 0.0036 17.1 0.6 1.4 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 KKK43484.1 - 0.0047 16.9 0.5 0.0049 16.9 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-RanBP PF00641.18 KKK43484.1 - 0.017 14.4 2.4 0.022 14.1 2.4 1.2 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 KKK43484.1 - 0.018 14.8 3.2 0.026 14.2 3.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Cpn60_TCP1 PF00118.24 KKK43485.1 - 5.8e-181 602.4 20.7 6.6e-181 602.2 20.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lactamase_B PF00753.27 KKK43487.1 - 8.6e-12 45.5 0.1 1.4e-11 44.8 0.1 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK43487.1 - 0.0062 16.1 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain rve PF00665.26 KKK43494.1 - 0.0093 16.2 0.0 0.0093 16.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain TypeIII_RM_meth PF12564.8 KKK43494.1 - 0.038 14.1 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit SIS PF01380.22 KKK43495.1 - 3.5e-42 143.4 1.7 3.1e-22 78.8 1.2 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KKK43495.1 - 2.1e-18 66.8 0.0 3.6e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KKK43495.1 - 1.1e-16 60.9 0.0 2.2e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KKK43495.1 - 0.0035 16.3 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Ras PF00071.22 KKK43498.1 - 5.4e-25 87.9 0.0 6e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK43498.1 - 1.6e-11 44.5 0.0 2.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK43498.1 - 0.0049 16.3 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family TrmB PF01978.19 KKK43499.1 - 0.029 14.3 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF900 PF05990.12 KKK43499.1 - 0.054 13.0 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) MtrB PF05440.12 KKK43499.1 - 0.083 13.3 0.2 51 4.4 0.0 3.3 2 1 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF2703 PF10865.8 KKK43499.1 - 0.12 12.6 0.8 0.4 10.9 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2703) HpaB_N PF11794.8 KKK43500.1 - 9.9e-90 300.9 0.0 1.3e-89 300.5 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 KKK43500.1 - 5.7e-53 179.0 0.0 7.9e-53 178.5 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Acyl-CoA_dh_M PF02770.19 KKK43500.1 - 0.0002 21.5 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HMGL-like PF00682.19 KKK43501.1 - 2.8e-48 164.8 0.4 3.8e-48 164.3 0.4 1.2 1 0 0 1 1 1 1 HMGL-like GH43_C2 PF17851.1 KKK43501.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Beta xylosidase C-terminal Concanavalin A-like domain SCAMP PF04144.13 KKK43502.1 - 0.44 10.8 7.8 5 7.4 0.0 2.5 3 0 0 3 3 3 0 SCAMP family PhaG_MnhG_YufB PF03334.14 KKK43502.1 - 0.68 10.2 11.7 3.7 7.9 2.2 3.1 3 1 0 3 3 3 0 Na+/H+ antiporter subunit DUF2754 PF10953.8 KKK43502.1 - 2.4 8.5 0.0 2.4 8.5 0.0 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2754) LRR_8 PF13855.6 KKK43503.1 - 1.7e-11 43.7 11.0 4.7e-07 29.5 3.6 2.8 1 1 1 2 2 2 2 Leucine rich repeat HEAT_2 PF13646.6 KKK43503.1 - 3.7e-07 30.4 0.1 6.9e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 HEAT repeats LRR_4 PF12799.7 KKK43503.1 - 1.6e-06 28.3 13.1 4.6e-06 26.9 0.6 3.3 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK43503.1 - 0.00029 20.9 10.9 1.9 9.3 0.1 4.8 5 0 0 5 5 5 3 Leucine Rich Repeat DUF1803 PF08820.10 KKK43503.1 - 0.0029 17.6 1.0 0.0087 16.1 1.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1803) LRR_6 PF13516.6 KKK43503.1 - 0.098 12.8 10.0 1.5 9.0 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat TPP_enzyme_N PF02776.18 KKK43504.1 - 4.5e-50 169.6 0.0 8.4e-49 165.5 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKK43504.1 - 6.2e-40 136.5 0.0 2.9e-39 134.3 0.0 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK43504.1 - 3.7e-32 110.9 0.0 9.4e-32 109.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 KKK43504.1 - 0.019 14.8 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DXP_synthase_N PF13292.6 KKK43504.1 - 0.069 12.3 0.0 0.67 9.1 0.0 2.4 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_N PF02776.18 KKK43505.1 - 1.6e-50 171.1 0.0 1.9e-49 167.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KKK43505.1 - 4.1e-40 137.1 0.8 1.2e-39 135.6 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK43505.1 - 1.2e-31 109.3 0.0 2.2e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 KKK43505.1 - 0.045 13.0 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_N PF02776.18 KKK43506.1 - 1.5e-47 161.4 0.0 2.6e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KKK43506.1 - 2.6e-33 114.7 0.0 5.5e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KKK43506.1 - 7.5e-15 55.0 1.4 2.1e-14 53.6 0.1 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 KKK43506.1 - 0.067 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit EzrA PF06160.12 KKK43506.1 - 0.09 10.9 0.7 0.17 10.0 0.2 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA URO-D PF01208.17 KKK43506.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) CCG PF02754.16 KKK43510.1 - 1.6e-16 60.3 13.5 7e-09 35.8 0.2 3.3 3 0 0 3 3 3 2 Cysteine-rich domain Fer4_8 PF13183.6 KKK43510.1 - 2.8e-07 30.9 7.4 2.8e-07 30.9 7.4 2.7 3 2 1 4 4 4 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43510.1 - 2.1e-06 27.8 6.8 2.1e-06 27.8 6.8 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK43510.1 - 6e-06 26.7 6.9 6e-06 26.7 6.9 3.2 3 2 2 5 5 5 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43510.1 - 1.7e-05 24.9 17.9 0.0002 21.4 9.8 3.7 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK43510.1 - 9.1e-05 23.0 7.3 9.1e-05 23.0 7.3 3.0 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK43510.1 - 0.05 13.8 5.9 0.66 10.2 0.2 2.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43510.1 - 0.097 13.6 17.9 0.19 12.7 2.1 3.8 4 1 0 4 4 4 0 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 KKK43510.1 - 0.96 10.3 19.6 0.33 11.8 1.2 4.0 4 1 1 5 5 5 0 4Fe-4S dicluster domain KGK PF08872.10 KKK43510.1 - 0.99 9.9 6.6 0.54 10.8 1.4 2.8 3 1 1 4 4 4 0 KGK domain RNA_pol_N PF01194.17 KKK43513.1 - 1.2e-25 89.5 0.3 1.4e-25 89.4 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KKK43513.1 - 0.028 14.6 0.1 0.042 14.1 0.1 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ribosomal_S6e PF01092.19 KKK43514.1 - 2.7e-34 117.8 0.5 3.7e-34 117.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S6e DUF1122 PF06557.11 KKK43515.1 - 0.038 13.4 0.1 0.08 12.4 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1122) Radical_SAM PF04055.21 KKK43516.1 - 1.1e-19 71.4 1.2 1.7e-17 64.3 0.2 2.9 2 1 0 2 2 2 2 Radical SAM superfamily B12-binding PF02310.19 KKK43516.1 - 7.1e-15 55.1 0.0 1.6e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain SAM_4 PF18017.1 KKK43516.1 - 0.033 14.1 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF4091 PF13320.6 KKK43517.1 - 2.9e-12 46.5 0.1 7.1e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4091) MetallophosN PF16371.5 KKK43517.1 - 0.0013 19.0 0.1 0.003 17.8 0.1 1.7 1 0 0 1 1 1 1 N terminal of Calcineurin-like phosphoesterase DUF3695 PF12494.8 KKK43517.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) LupA PF18242.1 KKK43518.1 - 0.13 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain NAPRTase_N PF17767.1 KKK43520.1 - 1.3e-40 138.6 0.8 3.1e-40 137.5 0.8 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 KKK43520.1 - 9.5e-16 58.2 0.5 6.9e-11 42.6 0.1 2.6 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 KKK43520.1 - 1.7e-12 47.5 0.4 5.4e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_C PF01729.19 KKK43520.1 - 0.0031 17.3 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KKK43520.1 - 0.033 14.2 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain CPSase_L_D3 PF02787.19 KKK43520.1 - 0.081 13.3 0.2 0.41 11.0 0.1 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Clr5 PF14420.6 KKK43520.1 - 0.2 11.9 0.5 0.45 10.8 0.5 1.5 1 0 0 1 1 1 0 Clr5 domain ECH_1 PF00378.20 KKK43521.1 - 4.1e-59 199.9 0.0 4.6e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK43521.1 - 5.2e-32 111.7 0.0 5.6e-28 98.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF5354 PF17305.2 KKK43521.1 - 0.049 13.8 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5354) CLP_protease PF00574.23 KKK43521.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Clp protease Cys_rich_CPCC PF14206.6 KKK43522.1 - 0.0033 17.2 0.2 0.0034 17.2 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich CPCC RNA_POL_M_15KD PF02150.16 KKK43522.1 - 0.029 14.2 0.7 0.042 13.7 0.7 1.3 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit DNA_ligase_ZBD PF03119.16 KKK43522.1 - 0.046 13.8 2.7 3.6 7.7 0.2 2.2 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain NADH-G_4Fe-4S_3 PF10588.9 KKK43522.1 - 0.047 13.2 1.8 1.9 8.1 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-ribbon_3 PF13248.6 KKK43522.1 - 0.055 12.9 1.6 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin PF00301.20 KKK43522.1 - 0.071 13.1 1.9 0.8 9.8 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin UPF0547 PF10571.9 KKK43522.1 - 0.09 12.9 2.8 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-ACC PF17848.1 KKK43522.1 - 0.28 11.3 4.6 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF3797 PF12677.7 KKK43522.1 - 0.33 10.9 0.3 0.33 10.9 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Pribosyltran PF00156.27 KKK43523.1 - 0.0009 18.8 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DNA_processg_A PF02481.15 KKK43524.1 - 2.9e-36 124.7 0.0 3.8e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A LDcluster4 PF18306.1 KKK43524.1 - 5.4e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 SLOG cluster4 family DUF4140 PF13600.6 KKK43529.1 - 0.00086 19.7 0.0 0.0025 18.2 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) SBBP PF06739.11 KKK43531.1 - 6.5e-10 38.9 28.4 0.0041 17.1 2.5 5.1 5 0 0 5 5 5 4 Beta-propeller repeat NHL PF01436.21 KKK43531.1 - 0.0019 18.1 6.2 9.7 6.4 0.1 5.3 5 0 0 5 5 5 2 NHL repeat DUF5122 PF17164.4 KKK43531.1 - 0.0029 17.9 8.2 0.21 11.9 1.3 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF5122) beta-propeller DUF4956 PF16316.5 KKK43532.1 - 1.9e-13 50.4 8.8 2.7e-13 49.9 8.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4956) Cytochrom_B_C PF00032.17 KKK43532.1 - 0.15 12.4 5.0 0.089 13.1 2.5 1.9 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD MgtC PF02308.16 KKK43532.1 - 0.81 10.1 12.7 1.4 9.3 12.7 1.4 1 0 0 1 1 1 0 MgtC family Cation_ATPase_C PF00689.21 KKK43532.1 - 5.9 6.6 11.6 12 5.5 6.7 2.3 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus VTC PF09359.10 KKK43533.1 - 4.7e-27 95.1 9.1 4.7e-27 95.1 9.1 1.9 1 1 1 2 2 2 1 VTC domain CotH PF08757.11 KKK43534.1 - 2e-49 168.9 26.5 7.6e-29 101.2 9.2 2.1 2 0 0 2 2 2 2 CotH kinase protein ELFV_dehydrog PF00208.21 KKK43537.1 - 1.2e-59 202.0 0.0 1.6e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KKK43537.1 - 1.6e-57 193.0 0.0 3.3e-57 192.0 0.0 1.6 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KKK43537.1 - 0.014 14.7 0.1 0.031 13.7 0.1 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KKK43537.1 - 0.015 15.7 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Bac_GDH PF05088.12 KKK43537.1 - 0.12 9.8 0.0 0.16 9.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 KKK43538.1 - 3.6e-63 213.5 0.1 4.7e-63 213.2 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KKK43538.1 - 6.6e-52 174.8 0.0 9.9e-52 174.2 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 KKK43538.1 - 4.3e-05 22.9 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 KKK43538.1 - 0.001 18.5 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 ThiF family AdoHcyase_NAD PF00670.21 KKK43538.1 - 0.019 15.0 0.8 0.045 13.8 0.7 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Gp_dh_N PF00044.24 KKK43538.1 - 0.2 12.0 1.4 0.77 10.1 1.4 2.0 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Bac_GDH PF05088.12 KKK43538.1 - 0.2 9.1 0.1 0.29 8.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase TrkA_N PF02254.18 KKK43538.1 - 0.31 11.3 1.4 0.6 10.4 0.4 2.0 2 0 0 2 2 2 0 TrkA-N domain LRR_4 PF12799.7 KKK43540.1 - 1.8e-50 168.0 89.6 4e-10 39.8 1.0 7.5 2 1 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK43540.1 - 9.9e-31 105.3 52.9 1.4e-06 27.9 2.2 7.4 3 1 4 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 KKK43540.1 - 1.8e-21 76.4 24.0 7e-09 35.4 3.7 4.4 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 KKK43540.1 - 1.1e-06 28.3 48.5 4 8.4 0.1 12.2 12 2 0 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.6 KKK43540.1 - 5.7e-06 26.0 53.2 0.31 11.2 0.2 11.7 11 1 1 12 12 12 6 Leucine Rich repeat LRR_3 PF07725.12 KKK43540.1 - 0.033 14.0 7.6 1.5 8.8 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_2 PF07723.13 KKK43540.1 - 0.037 14.7 14.9 25 5.7 0.0 8.4 10 2 1 11 11 11 0 Leucine Rich Repeat SAM_3 PF18016.1 KKK43540.1 - 0.075 12.9 6.6 0.089 12.6 0.3 4.0 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) DUF2322 PF10084.9 KKK43540.1 - 1.4 9.0 3.3 8.3 6.5 0.3 3.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) PMT2_N PF17987.1 KKK43540.1 - 6.5 7.0 10.7 25 5.1 0.7 4.2 1 1 4 5 5 5 0 Phosphoethanolamine N-methyltransferase 2 N-terminal zf-piccolo PF05715.13 KKK43541.1 - 0.00075 19.6 0.9 0.00075 19.6 0.9 1.5 2 0 0 2 2 2 1 Piccolo Zn-finger zf_UBZ PF18439.1 KKK43541.1 - 0.0014 18.2 1.9 0.73 9.5 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KKK43541.1 - 0.0014 18.6 3.7 0.0024 17.8 3.7 1.5 1 1 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 KKK43541.1 - 0.0019 18.3 6.3 0.0045 17.0 0.2 2.6 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 DNA_RNApol_7kD PF03604.13 KKK43541.1 - 0.0026 17.4 0.7 0.64 9.8 0.1 2.5 2 1 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.10 KKK43541.1 - 0.0055 16.4 8.2 0.071 12.8 0.7 2.7 3 0 0 3 3 3 2 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 KKK43541.1 - 0.0095 15.9 1.9 0.015 15.3 1.9 1.3 1 1 0 1 1 1 1 zinc-ribbons Zn-ribbon_8 PF09723.10 KKK43541.1 - 0.014 15.5 1.6 0.014 15.5 1.6 1.8 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 KKK43541.1 - 0.017 15.1 1.3 0.021 14.8 1.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KKK43541.1 - 0.02 14.3 6.0 1.4 8.4 0.4 3.0 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 KKK43541.1 - 0.025 14.5 1.0 0.044 13.7 1.0 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 KKK43541.1 - 0.027 14.6 0.7 0.04 14.1 0.7 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-HYPF PF07503.12 KKK43541.1 - 0.034 13.9 0.8 3.7 7.4 0.1 2.3 2 0 0 2 2 2 0 HypF finger zinc_ribbon_10 PF10058.9 KKK43541.1 - 0.035 13.8 4.3 0.036 13.8 2.7 1.9 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein FYDLN_acid PF09538.10 KKK43541.1 - 0.05 14.3 1.3 0.055 14.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NOB1_Zn_bind PF08772.11 KKK43541.1 - 0.085 13.0 2.3 0.11 12.6 2.3 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like TF_Zn_Ribbon PF08271.12 KKK43541.1 - 0.098 12.2 6.9 0.047 13.2 4.6 1.7 2 1 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_3 PF13878.6 KKK43541.1 - 0.12 12.2 1.0 0.5 10.2 0.0 2.1 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-NADH-PPase PF09297.11 KKK43541.1 - 0.12 12.0 3.2 1.2 8.9 0.0 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KKK43541.1 - 0.33 10.9 4.9 3.4 7.7 1.2 2.7 2 1 0 2 2 2 0 Nudix N-terminal PHD PF00628.29 KKK43541.1 - 0.35 10.8 5.5 1.4 8.8 3.9 2.3 2 1 0 2 2 2 0 PHD-finger Zn_ribbon_recom PF13408.6 KKK43541.1 - 0.35 11.4 2.4 2.1 8.9 2.4 2.0 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-H2C2_2 PF13465.6 KKK43541.1 - 0.47 11.0 4.9 4.5 7.9 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-FPG_IleRS PF06827.14 KKK43541.1 - 0.65 9.9 5.0 2.4 8.1 5.0 2.0 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Rubredoxin_2 PF18073.1 KKK43541.1 - 0.74 9.6 0.3 0.74 9.6 0.3 2.4 3 0 0 3 3 2 0 Rubredoxin metal binding domain zf-HIT PF04438.16 KKK43541.1 - 0.82 9.6 8.8 7.4 6.5 8.8 2.3 1 1 0 1 1 1 0 HIT zinc finger zf-C2H2 PF00096.26 KKK43541.1 - 1 9.9 4.3 2.5 8.8 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_2 PF13240.6 KKK43541.1 - 2 8.3 12.5 42 4.1 8.8 3.0 2 1 0 2 2 2 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 KKK43541.1 - 2 8.8 7.7 1.2 9.5 4.6 2.1 2 1 0 2 2 1 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.10 KKK43542.1 - 2.6e-05 23.8 4.1 0.035 13.8 0.3 2.1 2 0 0 2 2 2 2 A2L zinc ribbon domain HypA PF01155.19 KKK43542.1 - 0.00072 19.6 0.2 0.00078 19.4 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KKK43542.1 - 0.0058 16.6 1.0 0.0089 16.0 1.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon NRDD PF13597.6 KKK43542.1 - 0.013 14.3 0.3 0.014 14.2 0.3 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase CpXC PF14353.6 KKK43542.1 - 0.015 15.3 0.7 2 8.5 0.1 2.0 1 1 1 2 2 2 0 CpXC protein zf-C2H2 PF00096.26 KKK43542.1 - 0.016 15.7 7.4 0.043 14.3 0.8 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 KKK43542.1 - 0.018 14.5 4.2 0.29 10.6 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KKK43542.1 - 0.019 15.0 0.5 0.024 14.6 0.5 1.1 1 0 0 1 1 1 0 zinc-ribbons TFIIS_C PF01096.18 KKK43542.1 - 0.026 14.4 2.5 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C3HC4_3 PF13920.6 KKK43542.1 - 0.027 14.4 0.4 0.034 14.0 0.4 1.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KKK43542.1 - 0.029 14.6 0.1 0.034 14.3 0.1 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Rubredoxin PF00301.20 KKK43542.1 - 0.034 14.2 4.6 0.27 11.3 0.4 2.1 1 1 1 2 2 2 0 Rubredoxin UPF0547 PF10571.9 KKK43542.1 - 0.045 13.8 3.8 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 TF_Zn_Ribbon PF08271.12 KKK43542.1 - 0.054 13.0 6.2 1 8.9 0.8 2.1 1 1 0 2 2 2 0 TFIIB zinc-binding zf_UBZ PF18439.1 KKK43542.1 - 0.067 12.8 3.0 0.89 9.2 0.5 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Auto_anti-p27 PF06677.12 KKK43542.1 - 0.086 13.0 2.1 0.14 12.3 2.1 1.4 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rep_fac-A_C PF08646.10 KKK43542.1 - 0.1 12.3 0.9 0.11 12.2 0.9 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain Zn-ribbon_8 PF09723.10 KKK43542.1 - 0.11 12.6 4.8 0.34 11.1 4.9 1.7 1 1 1 2 2 2 0 Zinc ribbon domain DUF35_N PF12172.8 KKK43542.1 - 0.12 12.3 0.9 3.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) OrfB_Zn_ribbon PF07282.11 KKK43542.1 - 0.13 12.2 2.3 0.16 11.9 2.3 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.6 KKK43542.1 - 0.16 12.5 8.5 1.9 9.0 1.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Rubredoxin_2 PF18073.1 KKK43542.1 - 0.23 11.2 4.5 1.2 8.9 0.3 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-C2H2_4 PF13894.6 KKK43542.1 - 0.57 11.2 4.2 5.5 8.1 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_2 PF13240.6 KKK43542.1 - 0.61 9.9 9.2 18 5.2 9.2 2.2 1 1 0 1 1 1 0 zinc-ribbon domain tRNA-synt_2c PF01411.19 KKK43543.1 - 2.3e-15 56.1 0.1 3.8e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KKK43543.1 - 7e-10 38.8 0.5 1.4e-09 37.9 0.5 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PABP PF00658.18 KKK43543.1 - 0.04 14.1 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain Arch_flagellin PF01917.16 KKK43543.1 - 0.13 12.5 0.2 0.53 10.5 0.1 1.9 2 0 0 2 2 2 0 Archaebacterial flagellin Gln_deamidase_2 PF18626.1 KKK43544.1 - 0.066 13.5 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutaminase BNR_4 PF15892.5 KKK43545.1 - 0.0014 18.1 9.0 0.43 9.9 0.1 3.8 2 1 1 4 4 4 3 BNR repeat-containing family member BNR_2 PF13088.6 KKK43545.1 - 0.022 14.1 0.1 0.42 9.9 0.0 2.3 1 1 1 2 2 2 0 BNR repeat-like domain BNR PF02012.20 KKK43545.1 - 0.13 12.3 13.7 0.49 10.6 0.3 5.0 5 0 0 5 5 5 0 BNR/Asp-box repeat AMP-binding PF00501.28 KKK43546.1 - 1e-63 215.4 0.0 1.2e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK43546.1 - 0.00081 20.3 0.0 0.0015 19.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MOZART1 PF12554.8 KKK43546.1 - 0.013 15.3 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated PemK_toxin PF02452.17 KKK43547.1 - 9.1e-14 51.8 0.1 1e-13 51.7 0.1 1.0 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF3081 PF11280.8 KKK43547.1 - 0.0015 18.3 0.3 0.0028 17.4 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3081) DUF2281 PF10047.9 KKK43548.1 - 0.018 15.7 0.4 0.02 15.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) NIF3 PF01784.18 KKK43549.1 - 1.7e-23 83.5 0.4 2.1e-23 83.2 0.4 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Imm71 PF15602.6 KKK43549.1 - 0.0035 17.4 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Immunity protein 71 STT3_PglB_C PF18527.1 KKK43549.1 - 0.22 11.6 2.1 27 5.0 0.1 3.0 3 0 0 3 3 3 0 STT3/PglB C-terminal beta-barrel domain Hexapep PF00132.24 KKK43550.1 - 5.2e-08 32.3 6.1 1.1e-05 24.9 0.7 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK43550.1 - 4.1e-06 26.4 3.5 2.9e-05 23.7 0.1 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF438 PF04282.13 KKK43554.1 - 1.5e-20 72.9 0.8 2.4e-20 72.2 0.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF438) DUF1858 PF08984.11 KKK43554.1 - 3.1e-10 40.1 0.1 5.2e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1858) PARP_reg PF02877.14 KKK43554.1 - 0.00083 19.5 1.3 1.2 9.3 0.1 2.3 1 1 0 2 2 2 2 Poly(ADP-ribose) polymerase, regulatory domain Focal_AT PF03623.13 KKK43554.1 - 0.018 15.1 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Focal adhesion targeting region MINDY_DUB PF04424.13 KKK43554.1 - 0.1 12.6 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 MINDY deubiquitinase BBP1_C PF15272.6 KKK43554.1 - 0.13 12.1 1.9 1.1 9.0 2.0 2.0 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal PCNA_N PF00705.18 KKK43555.1 - 3.4e-21 75.3 2.0 3.4e-21 75.3 2.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KKK43555.1 - 1.5e-09 38.1 0.1 2e-08 34.5 0.0 2.4 1 1 1 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KKK43555.1 - 4.1e-06 26.4 0.9 1.5e-05 24.6 0.9 1.8 1 1 0 1 1 1 1 Rad9 Hus1 PF04005.12 KKK43555.1 - 0.016 14.3 0.1 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 Hus1-like protein BOF PF04076.13 KKK43556.1 - 8.6e-07 29.0 3.8 1.1e-06 28.6 3.8 1.2 1 0 0 1 1 1 1 Bacterial OB fold (BOF) protein Ten1_2 PF15490.6 KKK43556.1 - 1.3e-05 24.9 0.2 1.4e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit tRNA_anti-codon PF01336.25 KKK43556.1 - 0.0015 18.4 1.1 0.014 15.4 0.7 2.1 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain Rep_fac-A_3 PF08661.11 KKK43556.1 - 0.0063 16.9 0.3 0.0073 16.6 0.3 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 RMI2 PF16100.5 KKK43556.1 - 0.052 13.4 0.1 0.066 13.0 0.1 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 TFIIS_C PF01096.18 KKK43557.1 - 2.8e-16 59.1 5.1 2.8e-16 59.1 5.1 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 KKK43557.1 - 0.013 15.6 5.0 7.9 6.7 0.0 3.6 3 0 0 3 3 3 0 Zinc ribbon domain zf_C2H2_10 PF18414.1 KKK43557.1 - 0.16 11.5 0.2 0.16 11.5 0.2 3.3 4 0 0 4 4 4 0 C2H2 type zinc-finger OrfB_Zn_ribbon PF07282.11 KKK43557.1 - 1.1 9.3 10.3 1.7 8.6 2.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.7 KKK43557.1 - 1.5 8.8 13.0 0.11 12.5 3.5 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.16 KKK43557.1 - 3.1 7.7 13.7 2.5 8.1 4.5 3.4 3 1 0 3 3 3 0 RNA polymerases M/15 Kd subunit DZR PF12773.7 KKK43557.1 - 4.5 7.4 11.2 2.1e+02 2.0 11.3 2.9 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 KKK43557.1 - 7.9 6.5 13.0 1.7 8.6 0.9 3.5 4 0 0 4 4 4 0 zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 KKK43557.1 - 9.4 6.4 11.3 0.64 10.1 0.3 3.3 1 1 2 4 4 4 0 Transposase zinc-binding domain Ribosomal_S27e PF01667.17 KKK43558.1 - 1.1e-22 79.4 2.6 1.2e-22 79.3 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 zf-RING_14 PF17978.1 KKK43558.1 - 0.0052 17.2 0.3 0.0058 17.0 0.3 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF3797 PF12677.7 KKK43558.1 - 0.017 15.0 1.8 2.3 8.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) HypA PF01155.19 KKK43558.1 - 0.023 14.7 0.8 0.027 14.5 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 KKK43558.1 - 0.024 14.7 1.0 0.75 9.9 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger Sgf11 PF08209.11 KKK43558.1 - 0.034 13.7 1.9 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2HC5 PF06221.13 KKK43558.1 - 0.036 14.1 2.5 0.053 13.5 2.5 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-C2H2_12 PF18658.1 KKK43558.1 - 1.1 8.9 4.2 0.61 9.7 0.7 2.0 1 1 1 2 2 2 0 Zinc-finger C2H2-type FlpD PF02662.16 KKK43563.1 - 1.1e-53 180.4 0.0 1.3e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit Pyr_redox_2 PF07992.14 KKK43564.1 - 6.7e-29 101.0 0.0 2.5e-13 49.9 0.0 3.3 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK43564.1 - 2.2e-15 56.6 0.0 2.3e-06 27.7 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK43564.1 - 2.5e-15 56.8 0.0 3.3e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK43564.1 - 4.8e-14 52.3 0.6 6.7e-06 25.4 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Fer4_7 PF12838.7 KKK43564.1 - 1.3e-10 41.7 35.1 5.7e-08 33.2 8.6 4.4 4 1 2 6 6 6 4 4Fe-4S dicluster domain HI0933_like PF03486.14 KKK43564.1 - 3.2e-10 39.3 4.1 0.00095 18.0 0.2 3.5 2 1 1 3 3 3 2 HI0933-like protein Fer4 PF00037.27 KKK43564.1 - 4.1e-10 39.1 49.6 7.6e-07 28.7 3.5 5.8 7 0 0 7 7 5 4 4Fe-4S binding domain GIDA PF01134.22 KKK43564.1 - 5.9e-10 38.8 0.5 0.0011 18.1 0.0 3.4 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK43564.1 - 6.7e-10 38.7 1.0 1.9e-05 24.1 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK43564.1 - 1.1e-09 38.4 1.6 0.00097 18.8 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KKK43564.1 - 2.6e-08 33.4 0.2 0.0039 16.4 0.0 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KKK43564.1 - 2.8e-08 34.2 5.9 0.0011 19.4 0.0 3.9 4 1 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KKK43564.1 - 8.5e-08 31.7 0.0 0.0014 17.9 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KKK43564.1 - 1.5e-07 31.0 0.8 0.0072 15.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Fer4_9 PF13187.6 KKK43564.1 - 2.2e-06 27.7 8.0 2.2e-06 27.7 8.0 4.4 5 1 0 5 5 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43564.1 - 2.3e-06 27.4 56.2 0.0001 22.2 3.2 5.7 7 0 0 7 7 5 4 4Fe-4S binding domain Fer4_16 PF13484.6 KKK43564.1 - 3.2e-06 28.0 26.8 0.06 14.3 0.3 5.6 4 1 2 6 6 6 2 4Fe-4S double cluster binding domain Amino_oxidase PF01593.24 KKK43564.1 - 1.2e-05 24.9 0.0 0.29 10.4 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Fer4_2 PF12797.7 KKK43564.1 - 3.1e-05 23.8 47.5 0.0019 18.1 2.6 5.3 6 0 0 6 6 4 3 4Fe-4S binding domain Fer4_10 PF13237.6 KKK43564.1 - 4.4e-05 23.5 36.4 0.034 14.2 14.0 5.4 5 1 1 6 6 5 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43564.1 - 6.2e-05 23.0 11.6 6.2e-05 23.0 11.6 4.7 4 1 1 5 5 4 3 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 KKK43564.1 - 0.0047 16.9 0.9 5.8 6.9 0.1 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding Fer4_22 PF17179.4 KKK43564.1 - 0.033 15.0 25.5 0.73 10.7 0.4 5.0 5 0 0 5 5 5 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 KKK43564.1 - 0.043 12.8 0.0 1.4 7.9 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KKK43564.1 - 0.059 12.2 2.0 2.5 6.8 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_15 PF13459.6 KKK43564.1 - 0.55 11.0 18.6 1.2 10.0 0.4 3.9 4 0 0 4 4 3 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 KKK43564.1 - 0.91 10.2 33.7 0.35 11.5 4.5 4.9 4 0 0 4 4 4 0 4Fe-4S binding domain HTH_AsnC-type PF13404.6 KKK43565.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK43565.1 - 0.049 13.2 2.3 1.9 8.1 0.2 2.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding ABM PF03992.16 KKK43566.1 - 0.03 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase ECH_1 PF00378.20 KKK43567.1 - 1.3e-30 106.5 0.0 1.5e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK43567.1 - 2.1e-13 50.5 0.1 6.8e-13 48.8 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase gag-asp_proteas PF13975.6 KKK43567.1 - 0.022 15.3 0.0 0.037 14.6 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease 2TM PF13239.6 KKK43568.1 - 4.2e-15 55.8 80.4 1e-06 28.9 10.6 6.4 3 2 2 6 6 6 6 2TM domain RtcB PF01139.17 KKK43573.1 - 7.5e-29 101.1 0.1 8.1e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB BBL5 PF07289.11 KKK43573.1 - 0.076 12.0 0.0 0.083 11.9 0.0 1.0 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Archease PF01951.16 KKK43574.1 - 6.2e-39 133.4 1.7 6.9e-39 133.2 1.7 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) KH_2 PF07650.17 KKK43575.1 - 0.0018 18.1 0.2 0.0035 17.1 0.1 1.6 1 1 0 1 1 1 1 KH domain CarS-like PF01864.17 KKK43576.1 - 1.1e-32 113.4 18.7 2.6e-20 73.1 6.4 2.5 2 1 1 3 3 3 2 CDP-archaeol synthase CTP_transf_1 PF01148.20 KKK43576.1 - 9.7e-05 22.3 0.7 9.7e-05 22.3 0.7 3.1 3 1 0 3 3 3 3 Cytidylyltransferase family AAA_16 PF13191.6 KKK43577.1 - 0.0027 18.1 0.0 0.0032 17.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Kinesin PF00225.23 KKK43577.1 - 0.016 14.1 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain FGGY_N PF00370.21 KKK43580.1 - 2.6e-39 135.3 0.0 5.7e-39 134.1 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KKK43580.1 - 1.2e-20 74.0 0.0 1.8e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Phytochelatin_C PF09328.10 KKK43580.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) NMO PF03060.15 KKK43581.1 - 8.2e-47 160.2 0.9 1.2e-46 159.6 0.9 1.2 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KKK43581.1 - 1e-07 31.4 2.0 2e-07 30.4 2.0 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK43581.1 - 2.3e-07 30.2 3.8 0.0038 16.3 0.0 3.2 2 2 2 4 4 4 2 IMP dehydrogenase / GMP reductase domain DUF1729 PF08354.10 KKK43581.1 - 0.049 12.5 0.8 0.19 10.6 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1729) Succ_CoA_lig PF13607.6 KKK43582.1 - 1.3e-37 128.7 0.0 8.9e-37 126.0 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK43582.1 - 4.4e-17 62.6 0.0 1.9e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 KKK43582.1 - 1.7e-07 31.8 0.1 4.2e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain LOR PF04525.12 KKK43583.1 - 1.2e-14 54.3 2.6 2.3e-14 53.4 2.6 1.4 1 1 0 1 1 1 1 LURP-one-related Scramblase PF03803.15 KKK43583.1 - 0.00056 19.3 0.4 0.0038 16.5 0.4 1.9 1 1 0 1 1 1 1 Scramblase AMP-binding PF00501.28 KKK43585.1 - 2e-73 247.4 0.0 2.6e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK43585.1 - 1.3e-12 48.5 0.1 3.2e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAAP1 PF15335.6 KKK43585.1 - 0.13 12.8 0.2 0.56 10.8 0.1 2.0 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Met_10 PF02475.16 KKK43586.1 - 8.5e-51 172.5 0.0 1.1e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 KKK43586.1 - 1.4e-05 24.7 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KKK43586.1 - 0.00014 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TRM PF02005.16 KKK43586.1 - 0.0015 17.7 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Cons_hypoth95 PF03602.15 KKK43586.1 - 0.0039 16.9 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 KKK43586.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK43586.1 - 0.0099 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MnmE_helical PF12631.7 KKK43587.1 - 0.013 15.7 0.4 0.019 15.1 0.4 1.4 1 1 0 1 1 1 0 MnmE helical domain GATase1_like PF07090.11 KKK43587.1 - 0.021 14.2 0.0 5.2 6.4 0.0 2.7 3 0 0 3 3 3 0 Putative glutamine amidotransferase ABC_transp_aux PF09822.9 KKK43587.1 - 0.03 13.8 1.5 0.05 13.1 0.0 2.0 2 0 0 2 2 2 0 ABC-type uncharacterized transport system DUF4159 PF13709.6 KKK43587.1 - 0.056 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) UPF0020 PF01170.18 KKK43588.1 - 0.0023 17.6 0.0 0.23 11.1 0.0 2.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KKK43588.1 - 0.022 14.5 0.1 0.36 10.5 0.0 2.4 2 1 0 2 2 2 0 DNA methylase Methyltransf_15 PF09445.10 KKK43588.1 - 0.04 13.5 0.0 0.097 12.2 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase HhH-GPD PF00730.25 KKK43589.1 - 4.5e-27 94.6 0.0 6.6e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KKK43589.1 - 1.8e-09 37.0 0.0 1e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KKK43589.1 - 4.1e-05 24.1 0.1 0.43 11.2 0.1 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 KKK43589.1 - 0.0018 18.5 6.2 0.0031 17.8 6.2 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III LAGLIDADG_3 PF14528.6 KKK43590.1 - 0.00026 21.2 0.5 0.00088 19.5 0.0 2.2 2 0 0 2 2 2 1 LAGLIDADG-like domain DUF3606 PF12244.8 KKK43590.1 - 0.043 13.7 0.5 6.5 6.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) HTH_33 PF13592.6 KKK43590.1 - 0.047 13.3 1.3 9 6.0 0.1 3.2 3 0 0 3 3 3 0 Winged helix-turn helix PAS_9 PF13426.7 KKK43591.1 - 3.9e-62 207.0 20.9 1.6e-14 54.0 0.1 8.5 8 0 0 8 8 8 7 PAS domain PAS PF00989.25 KKK43591.1 - 7.1e-54 180.6 0.2 4.2e-12 46.1 0.0 8.5 8 0 0 8 8 8 7 PAS fold PAS_4 PF08448.10 KKK43591.1 - 1e-43 148.0 0.0 4.9e-06 26.8 0.0 8.4 8 0 0 8 8 8 7 PAS fold PAS_3 PF08447.12 KKK43591.1 - 2.5e-42 143.0 0.3 5.5e-11 42.6 0.0 7.5 7 0 0 7 7 7 5 PAS fold PAS_8 PF13188.7 KKK43591.1 - 1.1e-36 124.2 0.1 1.8e-07 31.0 0.0 7.5 7 0 0 7 7 7 5 PAS domain HATPase_c PF02518.26 KKK43591.1 - 4.5e-25 88.3 1.3 2e-24 86.2 0.2 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 KKK43591.1 - 2.6e-12 46.9 10.3 0.13 12.4 0.1 8.6 9 3 0 9 9 9 3 PAS fold HisKA PF00512.25 KKK43591.1 - 9.9e-12 44.7 0.9 5.9e-11 42.2 0.2 2.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KKK43591.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Cache_3-Cache_2 PF17201.4 KKK43591.1 - 0.073 12.3 1.6 14 4.8 0.0 3.4 4 0 0 4 4 4 0 Cache 3/Cache 2 fusion domain NDUFB11 PF17250.2 KKK43591.1 - 0.12 13.0 0.1 0.83 10.3 0.1 2.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit OmpH PF03938.14 KKK43591.1 - 0.19 12.1 20.8 2.1 8.7 0.3 6.3 6 1 0 6 6 6 0 Outer membrane protein (OmpH-like) Lactamase_B PF00753.27 KKK43593.1 - 2.7e-19 69.9 0.2 7.6e-19 68.5 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KKK43593.1 - 1.3e-11 44.9 2.9 2.1e-11 44.2 2.9 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 KKK43593.1 - 0.00012 21.7 0.4 0.00026 20.6 0.4 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK43593.1 - 0.013 15.4 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Rad51 PF08423.11 KKK43595.1 - 1.3e-05 24.6 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_22 PF13401.6 KKK43595.1 - 5.7e-05 23.4 0.2 0.00016 22.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK43595.1 - 0.0015 19.0 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Kinase-PolyVal PF18762.1 KKK43595.1 - 0.0025 17.8 1.3 0.31 11.0 0.3 2.3 2 0 0 2 2 2 1 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins AAA_25 PF13481.6 KKK43595.1 - 0.0032 17.1 0.0 0.011 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK43595.1 - 0.0089 15.8 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KKK43595.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.7 1 1 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 KKK43595.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 KKK43595.1 - 0.022 15.3 0.1 0.029 14.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 KKK43595.1 - 0.022 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 KKK43595.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKK43595.1 - 0.033 13.9 0.5 0.18 11.5 0.5 2.0 1 1 0 1 1 1 0 AAA domain DUF4923 PF16270.5 KKK43595.1 - 0.043 13.7 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) RsgA_GTPase PF03193.16 KKK43595.1 - 0.055 13.4 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PSY3 PF16836.5 KKK43595.1 - 0.055 13.0 1.5 0.18 11.3 1.5 1.9 1 1 0 1 1 1 0 Shu complex component Psy3, DNA-binding description AAA PF00004.29 KKK43595.1 - 0.07 13.6 0.1 0.23 11.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KKK43595.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RecA PF00154.21 KKK43595.1 - 0.18 11.3 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 recA bacterial DNA recombination protein Fe-ADH PF00465.19 KKK43596.1 - 4.6e-13 48.7 0.1 5.4e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK43596.1 - 1.8e-05 24.6 0.1 2.4e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Proteasome PF00227.26 KKK43601.1 - 5.7e-48 162.9 0.3 6.6e-48 162.7 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Nebulin PF00880.18 KKK43601.1 - 0.15 12.0 0.5 0.56 10.2 0.1 2.1 2 0 0 2 2 2 0 Nebulin repeat EamA PF00892.20 KKK43602.1 - 5.6e-29 101.1 39.9 2.6e-16 60.0 17.5 2.0 2 0 0 2 2 2 2 EamA-like transporter family Sugar_transport PF06800.12 KKK43602.1 - 3.7e-07 29.8 13.0 5.2e-07 29.3 13.0 1.2 1 0 0 1 1 1 1 Sugar transport protein HlyIII PF03006.20 KKK43602.1 - 0.099 12.3 17.6 0.39 10.4 5.5 2.7 1 1 0 2 2 2 0 Haemolysin-III related Halogen_Hydrol PF10112.9 KKK43602.1 - 0.18 11.8 0.0 0.18 11.8 0.0 3.0 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DMT_6 PF04342.12 KKK43602.1 - 7.2 6.9 21.7 0.45 10.7 0.6 4.0 3 2 1 4 4 4 0 Putative member of DMT superfamily (DUF486) DUF4173 PF13777.6 KKK43603.1 - 0.019 14.4 2.0 0.019 14.4 2.0 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4173) Aminotran_1_2 PF00155.21 KKK43604.1 - 1.9e-62 211.6 0.0 2.1e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KKK43604.1 - 0.037 12.6 0.0 0.061 11.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKK43604.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V DNA_binding_1 PF01035.20 KKK43605.1 - 1.5e-20 73.1 0.0 2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain mTERF PF02536.14 KKK43606.1 - 0.0045 16.0 1.4 0.0056 15.6 1.4 1.1 1 0 0 1 1 1 1 mTERF DUF1090 PF06476.12 KKK43606.1 - 0.024 14.7 0.9 0.04 14.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF2469 PF10611.9 KKK43606.1 - 0.027 15.0 0.0 0.056 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) DUF1308 PF07000.11 KKK43606.1 - 0.03 14.2 1.7 0.042 13.8 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Cnd1 PF12717.7 KKK43606.1 - 0.044 13.8 1.5 0.06 13.4 1.5 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF1690 PF07956.11 KKK43606.1 - 0.079 13.4 4.0 0.072 13.5 2.7 1.6 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) DASH_Dad3 PF08656.10 KKK43606.1 - 0.21 11.7 2.2 0.49 10.5 2.2 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad3 Phage_integrase PF00589.22 KKK43607.1 - 1e-06 28.7 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_integr_3 PF16795.5 KKK43607.1 - 0.00088 19.2 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 Archaeal phage integrase DUF4441 PF14536.6 KKK43607.1 - 1.3 9.2 12.9 0.043 14.0 2.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) Tet_res_leader PF08050.12 KKK43608.1 - 0.01 15.7 2.4 0.062 13.1 1.9 2.4 2 0 0 2 2 2 0 Tetracycline resistance leader peptide Herpes_BLRF2 PF05812.12 KKK43608.1 - 0.046 13.9 0.5 0.066 13.4 0.5 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TRAM PF01938.20 KKK43611.1 - 0.0011 18.9 0.2 0.0014 18.6 0.2 1.2 1 0 0 1 1 1 1 TRAM domain zinc_ribbon_2 PF13240.6 KKK43615.1 - 0.12 12.1 0.3 0.12 12.1 0.3 1.8 2 0 0 2 2 2 0 zinc-ribbon domain MtrH PF02007.18 KKK43617.1 - 0.0089 15.2 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit DUF4640 PF15480.6 KKK43617.1 - 0.083 12.6 3.2 0.21 11.3 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) ABC1 PF03109.16 KKK43617.1 - 4 7.6 6.2 1.9 8.7 0.3 3.2 2 1 2 4 4 4 0 ABC1 family FixO PF02433.15 KKK43617.1 - 4.8 6.6 7.6 2.5 7.5 1.5 2.5 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO SpoIIIAH PF12685.7 KKK43618.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein PemK_toxin PF02452.17 KKK43620.1 - 5.6e-16 58.9 0.1 6.2e-16 58.8 0.1 1.0 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF3667 PF12412.8 KKK43621.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) T2SSE PF00437.20 KKK43621.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein HTH_34 PF13601.6 KKK43622.1 - 1.1e-14 54.3 0.5 2.1e-14 53.5 0.2 1.5 1 1 1 2 2 2 1 Winged helix DNA-binding domain PadR PF03551.14 KKK43622.1 - 0.00019 21.3 0.1 0.00032 20.6 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 KKK43622.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HxlR PF01638.17 KKK43622.1 - 0.0034 17.2 0.1 0.0052 16.6 0.1 1.3 1 1 0 1 1 1 1 HxlR-like helix-turn-helix HTH_5 PF01022.20 KKK43622.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 KKK43622.1 - 0.059 13.9 0.0 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF3116 PF11313.8 KKK43622.1 - 0.21 11.5 3.3 1.2 9.1 3.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3116) Toxin_17 PF08086.11 KKK43623.1 - 0.055 13.7 0.1 0.055 13.7 0.1 1.6 2 0 0 2 2 2 0 Ergtoxin family PyrI PF01948.18 KKK43624.1 - 0.046 14.0 4.1 0.59 10.4 3.5 2.4 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain D5_N PF08706.11 KKK43625.1 - 4.3e-12 46.5 5.6 6.5e-12 46.0 3.1 2.6 2 1 0 2 2 2 1 D5 N terminal like Prim-Pol PF09250.11 KKK43625.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Cnn_1N PF07989.11 KKK43627.1 - 0.0037 17.4 2.0 0.0044 17.1 1.6 1.3 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 SpoOE-like PF09388.10 KKK43627.1 - 0.0089 15.9 2.6 0.1 12.5 0.5 2.1 2 0 0 2 2 2 1 Spo0E like sporulation regulatory protein MIT PF04212.18 KKK43627.1 - 0.011 15.8 0.4 0.013 15.6 0.4 1.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Spc24 PF08286.11 KKK43627.1 - 0.043 14.1 0.1 0.051 13.8 0.1 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 RHH_1 PF01402.21 KKK43628.1 - 0.00013 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF4250 PF14056.6 KKK43628.1 - 0.0054 16.7 0.1 0.007 16.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4250) HicB_lk_antitox PF15919.5 KKK43628.1 - 0.092 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Spc7 PF08317.11 KKK43629.1 - 0.00061 18.8 46.8 0.041 12.8 21.0 2.6 1 1 2 3 3 3 2 Spc7 kinetochore protein DUF812 PF05667.11 KKK43629.1 - 0.0035 16.3 19.9 0.0035 16.3 19.9 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF812) EzrA PF06160.12 KKK43629.1 - 0.0054 15.0 37.7 0.042 12.0 18.5 2.8 1 1 0 2 2 2 2 Septation ring formation regulator, EzrA ZapB PF06005.12 KKK43629.1 - 0.0097 16.3 1.5 0.0097 16.3 1.5 5.0 1 1 2 3 3 1 1 Cell division protein ZapB MarR PF01047.22 KKK43629.1 - 0.012 15.6 0.6 0.13 12.2 0.0 2.8 2 0 0 2 2 2 0 MarR family BRE1 PF08647.11 KKK43629.1 - 0.023 14.8 12.9 0.023 14.8 12.9 4.0 2 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase XhlA PF10779.9 KKK43629.1 - 0.025 14.8 3.6 0.025 14.8 3.6 5.2 2 2 5 7 7 7 0 Haemolysin XhlA TrmB PF01978.19 KKK43629.1 - 0.027 14.4 0.7 0.18 11.7 0.0 2.7 4 0 0 4 4 3 0 Sugar-specific transcriptional regulator TrmB DUF4472 PF14739.6 KKK43629.1 - 0.029 15.1 10.0 0.029 15.1 10.0 3.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4472) TMF_DNA_bd PF12329.8 KKK43629.1 - 0.049 13.6 1.7 0.049 13.6 1.7 5.5 2 2 3 5 5 4 0 TATA element modulatory factor 1 DNA binding HTH_Crp_2 PF13545.6 KKK43629.1 - 0.088 12.8 0.0 0.088 12.8 0.0 3.4 5 0 0 5 5 4 0 Crp-like helix-turn-helix domain LPP PF04728.13 KKK43629.1 - 0.089 13.2 0.8 0.089 13.2 0.8 4.4 3 1 1 4 4 4 0 Lipoprotein leucine-zipper FAM184 PF15665.5 KKK43629.1 - 0.16 11.8 40.2 0.035 13.9 28.3 3.0 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B UPF0184 PF03670.13 KKK43629.1 - 0.19 12.2 0.3 0.19 12.2 0.3 4.2 2 2 1 4 4 4 0 Uncharacterised protein family (UPF0184) DUF4200 PF13863.6 KKK43629.1 - 0.27 11.7 49.1 0.05 14.0 15.6 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 KKK43629.1 - 0.3 11.2 40.5 0.53 10.4 13.1 3.9 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein DUF1515 PF07439.11 KKK43629.1 - 0.65 10.0 20.0 0.19 11.7 4.6 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF1515) KASH_CCD PF14662.6 KKK43629.1 - 1 9.1 48.4 0.093 12.6 19.7 3.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH WXG100 PF06013.12 KKK43629.1 - 1.8 8.8 5.8 7.2 6.9 0.2 4.1 4 2 0 4 4 3 0 Proteins of 100 residues with WXG ATG16 PF08614.11 KKK43629.1 - 2.1 8.5 37.9 1.7e+02 2.3 25.9 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KKK43629.1 - 2.2 7.8 29.5 0.5 9.9 12.0 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit HAP1_N PF04849.13 KKK43629.1 - 2.2 7.4 41.5 5.2 6.2 29.9 2.9 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Sec34 PF04136.15 KKK43629.1 - 3 7.7 23.8 0.058 13.3 1.2 4.2 1 1 1 4 4 4 0 Sec34-like family Golgin_A5 PF09787.9 KKK43629.1 - 4.1 6.8 46.3 13 5.2 22.4 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 KKK43629.1 - 4.7 6.6 48.4 3.9 6.9 12.4 3.0 1 1 2 3 3 2 0 Hyaluronan mediated motility receptor N-terminal CALCOCO1 PF07888.11 KKK43629.1 - 6.1 5.6 41.3 1.1 8.0 22.2 2.3 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Allexi_40kDa PF05549.11 KKK43629.1 - 7.3 6.0 23.2 0.097 12.2 5.3 3.1 1 1 2 3 3 3 0 Allexivirus 40kDa protein AcylCoA_dehyd_C PF12186.8 KKK43629.1 - 7.6 6.7 9.0 3.3 7.9 0.2 4.1 1 1 1 4 4 4 0 Acyl-CoA dehydrogenase C terminal LRR_8 PF13855.6 KKK43631.1 - 9e-20 70.2 27.6 9.2e-11 41.3 4.6 4.3 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KKK43631.1 - 2.6e-13 49.9 39.4 0.00011 22.5 4.5 5.0 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK43631.1 - 7.4e-05 22.8 21.7 0.77 10.5 0.4 6.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_5 PF13306.6 KKK43631.1 - 0.14 12.2 4.4 3.6 7.6 1.0 2.5 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) OHA PF14418.6 KKK43631.1 - 0.27 11.1 1.9 20 5.1 0.2 3.0 2 1 1 3 3 3 0 OST-HTH Associated domain LRR_9 PF14580.6 KKK43631.1 - 0.33 10.4 13.8 2 7.9 1.1 3.2 1 1 2 3 3 3 0 Leucine-rich repeat PadR PF03551.14 KKK43634.1 - 3.4e-17 62.2 0.0 7.5e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family RTP PF02334.16 KKK43634.1 - 0.0013 19.3 0.7 0.0023 18.5 0.1 1.7 1 1 0 1 1 1 1 Replication terminator protein HxlR PF01638.17 KKK43634.1 - 0.0019 18.0 0.2 0.0052 16.6 0.1 1.8 2 0 0 2 2 2 1 HxlR-like helix-turn-helix zinc_ribbon_15 PF17032.5 KKK43634.1 - 0.0088 16.8 0.2 0.013 16.2 0.2 1.4 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 KKK43634.1 - 0.035 14.1 0.2 0.053 13.6 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon TrmB PF01978.19 KKK43634.1 - 0.049 13.5 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 KKK43634.1 - 0.059 13.3 0.1 0.51 10.3 0.1 2.2 1 1 0 1 1 1 0 MarR family HTH_34 PF13601.6 KKK43634.1 - 0.07 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Replic_Relax PF13814.6 KKK43634.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation CCDC84 PF14968.6 KKK43634.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 DNA_RNApol_7kD PF03604.13 KKK43634.1 - 0.15 11.7 1.3 6.7 6.5 0.1 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit 2TM PF13239.6 KKK43635.1 - 9.5e-12 45.1 29.4 3.8e-07 30.3 6.4 2.2 1 1 1 2 2 2 2 2TM domain Halogen_Hydrol PF10112.9 KKK43635.1 - 0.024 14.7 0.1 0.024 14.7 0.1 2.1 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2244 PF10003.9 KKK43635.1 - 0.031 14.0 14.0 0.37 10.5 0.2 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3021 PF11457.8 KKK43635.1 - 0.2 12.0 18.6 0.36 11.2 18.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) PAP2 PF01569.21 KKK43636.1 - 5.2e-18 65.1 4.2 5.2e-18 65.1 4.2 1.9 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKK43636.1 - 6.8e-12 45.5 5.1 6.8e-12 45.5 5.1 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 KKK43636.1 - 6.1e-05 23.5 6.9 6.1e-05 23.5 6.9 2.4 2 0 0 2 2 2 1 PAP2 superfamily C-terminal Prominin PF05478.11 KKK43636.1 - 0.06 11.3 2.0 0.089 10.7 2.0 1.2 1 0 0 1 1 1 0 Prominin DUF2628 PF10947.8 KKK43636.1 - 1 9.7 13.1 0.19 12.1 6.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Nitroreductase PF00881.24 KKK43637.1 - 4e-26 92.1 0.1 5.6e-15 55.8 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 KKK43637.1 - 1.6e-08 34.4 0.1 0.00017 21.3 0.2 2.6 2 1 0 2 2 2 2 Putative TM nitroreductase DUF4651 PF15513.6 KKK43637.1 - 0.14 12.0 0.0 13 5.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4651) Fe_dep_repress PF01325.19 KKK43637.1 - 0.15 12.2 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Nitroreductase PF00881.24 KKK43638.1 - 1.4e-23 83.8 0.0 3.6e-13 49.9 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 KKK43638.1 - 1.1e-09 38.2 0.3 0.049 13.2 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase SepF PF04472.12 KKK43639.1 - 1.8e-06 28.1 0.0 2.2e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Cell division protein SepF HATPase_c PF02518.26 KKK43640.1 - 3.2e-14 53.4 0.3 6e-14 52.5 0.2 1.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK43640.1 - 4.5e-05 23.4 0.0 6.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain YhdX PF17444.2 KKK43640.1 - 0.091 12.6 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized YhdX-like 4HBT PF03061.22 KKK43644.1 - 2.7e-08 34.0 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KKK43644.1 - 0.026 14.8 0.0 0.038 14.2 0.0 1.3 1 1 0 1 1 1 0 Thioesterase-like superfamily Aldo_ket_red PF00248.21 KKK43645.1 - 8.2e-28 97.4 0.0 1e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BPD_transp_1 PF00528.22 KKK43646.1 - 1.5e-05 24.9 2.6 1.5e-05 24.8 2.6 1.0 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component HU-CCDC81_bac_2 PF18175.1 KKK43647.1 - 0.007 16.2 0.2 0.018 14.9 0.1 1.7 1 1 1 2 2 2 1 CCDC81-like prokaryotic HU domain 2 DUF760 PF05542.11 KKK43647.1 - 0.033 14.5 0.2 0.036 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF760) Peptidase_M1 PF01433.20 KKK43648.1 - 6.6e-15 55.3 1.4 1.1e-14 54.5 1.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M20 PF01546.28 KKK43652.1 - 4.2e-13 49.5 0.0 5.7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK43652.1 - 9e-09 35.2 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 KKK43652.1 - 0.0011 18.0 0.0 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 KKK43652.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 OST3_OST6 PF04756.13 KKK43653.1 - 4.2e-10 39.4 9.7 5.6e-10 39.0 9.7 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family PTPS_related PF10131.9 KKK43653.1 - 1.5 7.0 9.6 2.1 6.6 9.6 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein RDD PF06271.12 KKK43653.1 - 3.3 7.9 10.4 1.6 8.9 6.3 2.0 2 0 0 2 2 2 0 RDD family SNARE PF05739.19 KKK43653.1 - 4.4 7.4 6.1 3.8 7.6 0.8 2.4 2 0 0 2 2 2 0 SNARE domain NAD_kinase PF01513.21 KKK43654.1 - 1.8e-35 122.6 0.0 2.1e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KKK43654.1 - 0.0001 21.9 0.0 0.0008 19.0 0.0 2.2 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DeoRC PF00455.22 KKK43654.1 - 0.012 15.6 1.7 0.026 14.5 0.1 2.2 2 1 2 4 4 4 0 DeoR C terminal sensor domain Retrotran_gag_2 PF14223.6 KKK43654.1 - 0.059 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type GCV_H PF01597.19 KKK43655.1 - 7.6e-26 90.4 0.3 2e-25 89.1 0.3 1.6 1 1 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KKK43655.1 - 0.012 15.4 0.1 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme Phi29_Phage_SSB PF17427.2 KKK43655.1 - 0.051 13.8 0.0 0.061 13.5 0.0 1.1 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein RnfC_N PF13375.6 KKK43655.1 - 0.073 13.0 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain MAF_flag10 PF01973.18 KKK43656.1 - 1.4e-12 47.7 0.1 2.3e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF115 AntA PF08346.12 KKK43656.1 - 0.27 11.8 3.2 8.3 7.1 0.9 2.6 2 0 0 2 2 2 0 AntA/AntB antirepressor Rad51 PF08423.11 KKK43657.1 - 3.2e-35 121.6 0.0 3.7e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KKK43657.1 - 1.1e-06 28.1 1.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 KaiC AAA PF00004.29 KKK43657.1 - 8.5e-05 23.0 0.4 0.00026 21.4 0.4 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KKK43657.1 - 0.00054 19.7 0.2 0.038 13.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 KKK43657.1 - 0.0044 16.5 0.0 0.017 14.6 0.0 1.8 1 1 0 1 1 1 1 recA bacterial DNA recombination protein PduV-EutP PF10662.9 KKK43657.1 - 0.0069 16.1 0.6 0.091 12.5 0.0 2.6 2 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KKK43657.1 - 0.0073 16.3 2.7 0.012 15.5 2.7 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KKK43657.1 - 0.051 13.2 0.0 0.095 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK43657.1 - 0.06 13.4 1.5 0.18 11.8 0.8 2.2 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpc34 PF05158.12 KKK43658.1 - 0.025 14.0 1.5 0.079 12.3 0.2 2.0 1 1 1 2 2 2 0 RNA polymerase Rpc34 subunit zf-CHCC PF10276.9 KKK43658.1 - 0.032 14.3 0.4 0.062 13.4 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KKK43658.1 - 0.068 13.1 0.1 0.068 13.1 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Glutaredoxin PF00462.24 KKK43658.1 - 0.083 13.1 1.6 0.37 11.0 0.3 2.4 2 0 0 2 2 2 0 Glutaredoxin DUF4829 PF16111.5 KKK43658.1 - 0.13 13.0 3.9 0.093 13.5 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4829) FtsJ PF01728.19 KKK43659.1 - 4.5e-43 147.4 0.1 5.2e-43 147.2 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KKK43659.1 - 0.0013 18.5 0.9 0.0051 16.6 0.9 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK43659.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 KKK43660.1 - 9.4e-93 311.4 2.1 1.1e-92 311.1 2.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KKK43660.1 - 0.00015 21.6 0.2 0.00026 20.8 0.2 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 KKK43660.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KKK43660.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain AbrB_C PF18277.1 KKK43660.1 - 0.035 13.7 0.1 0.14 11.8 0.1 2.1 1 0 0 1 1 1 0 AbrB C-terminal domain AviRa PF11599.8 KKK43660.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa zf-RING_5 PF14634.6 KKK43660.1 - 0.3 11.1 1.7 0.7 9.9 1.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 KKK43660.1 - 1.4 8.4 4.1 18 4.9 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rad51 PF08423.11 KKK43661.1 - 5.6e-10 38.9 0.1 7.3e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_24 PF13479.6 KKK43661.1 - 3.7e-08 33.3 0.4 7e-08 32.4 0.1 1.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 KKK43661.1 - 7.2e-05 22.2 1.8 0.00017 21.0 1.8 1.6 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.6 KKK43661.1 - 0.0069 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RecA PF00154.21 KKK43661.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 1 0 1 1 1 0 recA bacterial DNA recombination protein AAA_22 PF13401.6 KKK43661.1 - 0.056 13.7 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK43661.1 - 0.08 12.5 0.0 5.3 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KKK43661.1 - 0.11 12.5 0.4 0.29 11.1 0.0 1.8 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF5603 PF18231.1 KKK43662.1 - 0.011 16.1 1.6 0.034 14.4 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5603) FtsJ PF01728.19 KKK43663.1 - 1.3e-10 41.7 0.0 2.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 KKK43663.1 - 3.9e-08 32.9 0.2 9.6e-08 31.6 0.2 1.7 1 0 0 1 1 1 1 S4 domain Fibrillarin PF01269.17 KKK43663.1 - 0.024 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_11 PF08241.12 KKK43663.1 - 0.094 13.4 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KKK43663.1 - 0.1 13.3 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF123 PF01986.16 KKK43667.1 - 1.8e-27 95.7 0.0 2.3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF123 GIY-YIG PF01541.24 KKK43667.1 - 0.065 13.5 1.4 0.14 12.4 1.2 1.8 1 1 0 1 1 1 0 GIY-YIG catalytic domain adh_short_C2 PF13561.6 KKK43668.1 - 2.4e-37 128.8 1.4 3.5e-37 128.2 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK43668.1 - 1.2e-36 126.0 2.2 2e-36 125.3 2.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK43668.1 - 6.9e-16 58.7 1.0 1.3e-15 57.7 0.9 1.5 1 1 0 1 1 1 1 KR domain Oleosin PF01277.17 KKK43669.1 - 0.00042 20.1 0.1 0.00072 19.3 0.1 1.3 1 0 0 1 1 1 1 Oleosin Romo1 PF10247.9 KKK43669.1 - 0.011 16.1 5.8 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 LapA_dom PF06305.11 KKK43669.1 - 0.08 12.8 1.7 10 6.0 0.0 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF4199 PF13858.6 KKK43669.1 - 0.26 11.7 20.1 0.17 12.3 12.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) DUF2070 PF09843.9 KKK43669.1 - 0.38 9.0 5.0 0.48 8.7 5.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UPF0154 PF03672.13 KKK43669.1 - 0.56 10.3 6.0 0.61 10.2 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF92 PF01940.16 KKK43669.1 - 1.2 8.5 5.3 0.084 12.3 0.3 1.5 2 0 0 2 2 2 0 Integral membrane protein DUF92 Robl_LC7 PF03259.17 KKK43670.1 - 9.2e-12 44.6 0.0 1.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain GatB_Yqey PF02637.18 KKK43671.1 - 3.7e-37 127.5 1.9 5.7e-37 126.9 1.9 1.3 1 0 0 1 1 1 1 GatB domain GatB_N PF02934.15 KKK43671.1 - 6.7e-29 101.1 0.2 1.1e-28 100.4 0.2 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain MotY_N PF18393.1 KKK43671.1 - 0.064 13.4 0.1 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 MotY N-terminal domain Methyltransf_25 PF13649.6 KKK43673.1 - 1.3e-21 77.1 0.0 2.6e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK43673.1 - 3.7e-21 75.5 0.0 5.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK43673.1 - 4.9e-20 72.0 0.0 8.6e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK43673.1 - 1.1e-18 67.6 0.0 1.8e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK43673.1 - 2.8e-17 62.8 0.0 6.4e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK43673.1 - 1.3e-15 57.9 0.0 2.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KKK43673.1 - 2.5e-08 33.6 0.0 6.1e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KKK43673.1 - 3.9e-07 30.0 0.0 5.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KKK43673.1 - 5e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KKK43673.1 - 7.6e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KKK43673.1 - 1.6e-05 24.4 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 KKK43673.1 - 2e-05 23.3 0.0 2.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 KKK43673.1 - 0.0016 18.4 0.0 0.015 15.2 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 KKK43673.1 - 0.003 17.2 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 KKK43673.1 - 0.0038 16.4 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase HsbA PF12296.8 KKK43673.1 - 0.0051 17.2 0.1 0.0094 16.4 0.1 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A RrnaAD PF00398.20 KKK43673.1 - 0.0051 15.9 0.0 0.078 12.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 KKK43673.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KKK43673.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_9 PF08003.11 KKK43673.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pox_MCEL PF03291.16 KKK43673.1 - 0.016 14.3 0.1 0.069 12.3 0.0 2.0 2 0 0 2 2 2 0 mRNA capping enzyme N2227 PF07942.12 KKK43673.1 - 0.035 13.3 0.1 0.16 11.1 0.0 1.9 1 1 1 2 2 2 0 N2227-like protein MetW PF07021.12 KKK43673.1 - 0.046 13.3 0.0 0.095 12.3 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 KKK43673.1 - 0.057 13.1 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 KKK43673.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AHSA1 PF08327.11 KKK43674.1 - 3.8e-15 56.2 0.1 4.3e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein SAC3 PF12209.8 KKK43674.1 - 0.012 15.7 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain RNA_pol_Rpb1_1 PF04997.12 KKK43677.1 - 8.3e-97 324.3 0.7 1e-96 324.0 0.1 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KKK43677.1 - 2e-71 239.6 0.1 9.6e-71 237.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KKK43677.1 - 2.7e-28 98.9 0.0 5.5e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KKK43677.1 - 8.8e-27 93.2 0.0 2.1e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 KKK43677.1 - 1.8e-21 76.8 0.0 3.3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 GreA_GreB_N PF03449.15 KKK43680.1 - 0.045 13.9 0.3 0.051 13.7 0.3 1.1 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal DUF362 PF04015.12 KKK43681.1 - 4.7e-24 85.8 0.1 7.4e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF362) MFS_1 PF07690.16 KKK43682.1 - 5.6e-34 117.6 87.6 2.8e-26 92.3 53.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KKK43682.1 - 0.033 12.8 45.4 0.14 10.6 16.7 3.1 1 1 2 3 3 3 0 MFS/sugar transport protein DUF1634 PF07843.11 KKK43683.1 - 0.039 14.0 6.0 0.61 10.2 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1634) DUF3290 PF11694.8 KKK43683.1 - 0.89 9.5 7.0 0.3 11.0 2.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) DUF2116 PF09889.9 KKK43683.1 - 1.5 8.8 5.3 7.2 6.7 0.3 2.7 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2207 PF09972.9 KKK43683.1 - 9 4.9 9.6 37 2.9 9.6 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PALP PF00291.25 KKK43686.1 - 7.5e-50 170.0 0.1 8.5e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyr_redox PF00070.27 KKK43686.1 - 4.9 7.8 7.5 25 5.5 0.5 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AAA_22 PF13401.6 KKK43688.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 KKK43688.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Microtubule binding AAA_16 PF13191.6 KKK43688.1 - 0.14 12.5 0.0 0.22 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KKK43688.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ArsA_HSP20 PF17886.1 KKK43689.1 - 1e-08 34.6 0.0 1.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 KKK43689.1 - 2.6e-06 27.5 0.3 2.2e-05 24.5 0.3 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PIH1_CS PF18201.1 KKK43689.1 - 0.0066 16.8 0.1 0.0098 16.3 0.1 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain GvpH PF05455.11 KKK43689.1 - 0.0088 16.1 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 1 GvpH PAP2 PF01569.21 KKK43690.1 - 4.8e-22 78.2 0.0 4.8e-22 78.2 0.0 2.8 4 0 0 4 4 4 1 PAP2 superfamily PAP2_3 PF14378.6 KKK43690.1 - 0.013 15.2 6.6 0.014 15.1 0.0 3.4 3 1 0 3 3 3 0 PAP2 superfamily DUF3185 PF11381.8 KKK43690.1 - 0.02 14.9 2.0 0.02 14.9 2.0 3.1 4 2 1 5 5 5 0 Protein of unknown function (DUF3185) EamA PF00892.20 KKK43691.1 - 7.5e-26 90.9 42.1 4e-14 53.0 13.4 2.9 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KKK43691.1 - 0.0052 16.1 24.6 0.0071 15.6 4.9 2.7 1 1 2 3 3 3 2 Purine nucleobase transmembrane transport Redoxin PF08534.10 KKK43694.1 - 1.3e-07 31.5 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KKK43694.1 - 1.6e-07 31.3 0.0 1.9e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Chordopox_A30L PF06015.12 KKK43696.1 - 0.094 12.5 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Guanylate_kin PF00625.21 KKK43697.1 - 5.7e-13 48.9 0.0 7.3e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase CoaE PF01121.20 KKK43697.1 - 0.0024 17.6 0.3 0.0024 17.6 0.3 1.4 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_18 PF13238.6 KKK43697.1 - 0.058 13.9 0.8 0.21 12.2 0.8 1.8 1 1 0 1 1 1 0 AAA domain SepF PF04472.12 KKK43697.1 - 0.061 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Cell division protein SepF AAA_29 PF13555.6 KKK43697.1 - 0.071 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A22 PF04848.13 KKK43697.1 - 0.081 13.0 1.1 0.4 10.8 1.1 1.9 1 1 0 1 1 1 0 Poxvirus A22 protein AAA_33 PF13671.6 KKK43697.1 - 0.19 11.9 0.4 3.7 7.7 0.4 2.4 1 1 0 1 1 1 0 AAA domain Fe_dep_repress PF01325.19 KKK43698.1 - 1e-13 51.3 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Fe_dep_repr_C PF02742.15 KKK43698.1 - 3.3e-12 46.3 0.6 5.3e-12 45.6 0.6 1.4 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HTH_Crp_2 PF13545.6 KKK43698.1 - 6.8e-08 32.4 0.0 1.5e-07 31.3 0.0 1.6 2 0 0 2 2 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 KKK43698.1 - 4.7e-07 29.6 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KKK43698.1 - 5.5e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KKK43698.1 - 1.8e-05 25.0 0.0 6.8e-05 23.1 0.0 1.9 1 1 1 2 2 2 1 Transcriptional regulator LexA_DNA_bind PF01726.16 KKK43698.1 - 1.8e-05 24.4 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 LexA DNA binding domain MarR_2 PF12802.7 KKK43698.1 - 4.1e-05 23.4 0.0 6.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.6 KKK43698.1 - 4.3e-05 23.4 0.1 0.00012 22.0 0.1 2.0 1 1 0 1 1 1 1 Winged helix-turn-helix HTH_36 PF13730.6 KKK43698.1 - 0.00012 22.0 0.0 0.0003 20.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 KKK43698.1 - 0.00034 21.1 0.0 0.00089 19.7 0.0 1.8 2 0 0 2 2 1 1 Winged helix DNA-binding domain CARD PF00619.21 KKK43698.1 - 0.0004 20.3 0.4 0.021 14.8 0.2 2.4 1 1 0 1 1 1 1 Caspase recruitment domain FeoC PF09012.10 KKK43698.1 - 0.00046 20.2 0.1 0.0011 18.9 0.1 1.8 1 1 0 1 1 1 1 FeoC like transcriptional regulator HTH_5 PF01022.20 KKK43698.1 - 0.00054 19.8 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 KKK43698.1 - 0.00096 19.0 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Phage_rep_O PF04492.13 KKK43698.1 - 0.0014 19.2 0.1 0.0028 18.2 0.1 1.6 1 0 0 1 1 1 1 Bacteriophage replication protein O DUF2250 PF10007.9 KKK43698.1 - 0.0017 18.4 0.1 0.0032 17.5 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) TFIIE_alpha PF02002.17 KKK43698.1 - 0.0028 17.5 0.4 0.016 15.1 0.4 2.1 1 1 0 1 1 1 1 TFIIE alpha subunit HTH_IclR PF09339.10 KKK43698.1 - 0.0047 16.7 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_38 PF13936.6 KKK43698.1 - 0.0058 16.4 0.0 0.054 13.3 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain GerE PF00196.19 KKK43698.1 - 0.0068 15.9 0.1 0.02 14.5 0.0 1.8 2 0 0 2 2 1 1 Bacterial regulatory proteins, luxR family DUF505 PF04458.12 KKK43698.1 - 0.013 13.9 0.1 0.013 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) AbiEi_4 PF13338.6 KKK43698.1 - 0.019 15.1 0.0 0.079 13.1 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HTH_1 PF00126.27 KKK43698.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family B-block_TFIIIC PF04182.12 KKK43698.1 - 0.02 15.1 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Crp PF00325.20 KKK43698.1 - 0.02 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family GntR PF00392.21 KKK43698.1 - 0.031 13.9 0.0 0.084 12.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 KKK43698.1 - 0.039 13.9 0.3 0.086 12.8 0.1 1.8 2 0 0 2 2 1 0 HTH domain HTH_29 PF13551.6 KKK43698.1 - 0.048 13.7 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 KKK43698.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Put_DNA-bind_N PF06971.13 KKK43698.1 - 0.067 13.2 0.2 0.26 11.4 0.1 2.1 2 0 0 2 2 1 0 Putative DNA-binding protein N-terminus Tfb5 PF06331.12 KKK43698.1 - 0.077 13.0 3.4 1.4 9.0 0.4 3.2 2 1 1 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 eIF-5_eIF-2B PF01873.17 KKK43698.1 - 0.082 12.8 0.5 2.7 7.9 0.3 2.2 1 1 1 2 2 2 0 Domain found in IF2B/IF5 Dimerisation PF08100.11 KKK43698.1 - 0.088 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain HTH_23 PF13384.6 KKK43698.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 KKK43698.1 - 0.093 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4863 PF16155.5 KKK43698.1 - 0.1 12.4 0.0 1.6 8.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4863) Mrr_N PF14338.6 KKK43698.1 - 0.16 12.1 1.1 0.71 10.0 0.2 2.4 2 1 0 3 3 3 0 Mrr N-terminal domain Chordopox_A30L PF06015.12 KKK43699.1 - 0.066 13.0 0.3 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Chordopoxvirus A30L protein Aminotran_1_2 PF00155.21 KKK43703.1 - 1.1e-57 195.9 0.0 1.2e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK43703.1 - 1.6e-05 24.1 0.0 0.00023 20.3 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Alliinase_C PF04864.13 KKK43703.1 - 4.3e-05 22.6 0.0 5.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Allinase DegT_DnrJ_EryC1 PF01041.17 KKK43703.1 - 0.00029 20.3 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KKK43703.1 - 0.094 11.2 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 KKK43703.1 - 0.12 11.0 0.0 0.25 10.0 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-III Beta_elim_lyase PF01212.21 KKK43703.1 - 0.13 11.5 0.0 0.36 10.0 0.0 1.8 1 1 1 2 2 2 0 Beta-eliminating lyase AAA_26 PF13500.6 KKK43706.1 - 1.5e-24 87.0 0.0 2.1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 KKK43706.1 - 2e-24 85.4 0.1 3.5e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 DRTGG domain CbiA PF01656.23 KKK43706.1 - 7.5e-07 29.3 0.0 3.1e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Hpr_kinase_N PF02603.16 KKK43706.1 - 0.0024 17.9 0.0 0.0072 16.3 0.0 1.9 1 0 0 1 1 1 1 HPr Serine kinase N terminus ATP-grasp_5 PF13549.6 KKK43707.1 - 4.1e-36 124.5 0.0 4.5e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain Radical_SAM PF04055.21 KKK43709.1 - 2.4e-19 70.3 0.0 4.6e-19 69.4 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK43709.1 - 1.4e-05 25.4 0.0 3.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain zf-ribbon_3 PF13248.6 KKK43709.1 - 0.018 14.4 9.3 0.51 9.8 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KKK43709.1 - 0.029 14.5 3.1 1 9.6 0.9 3.4 2 1 1 3 3 3 0 Zinc ribbon domain DZR PF12773.7 KKK43709.1 - 0.087 12.9 0.2 0.087 12.9 0.2 2.9 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK43709.1 - 0.31 10.8 0.1 0.31 10.8 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-IS66 PF13005.7 KKK43709.1 - 0.68 10.4 3.4 15 6.0 0.0 2.9 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-C4_Topoisom PF01396.19 KKK43709.1 - 2.3 8.1 9.4 3.2 7.6 0.3 2.9 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF3377 PF11857.8 KKK43710.1 - 0.73 9.8 13.4 19 5.3 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3377) DAO PF01266.24 KKK43711.1 - 2.2e-53 182.1 0.0 2.9e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KKK43711.1 - 3.9e-22 78.5 0.1 8.1e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KKK43711.1 - 9.6e-07 28.2 0.2 5.7e-06 25.7 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK43711.1 - 0.00066 19.9 0.2 0.0014 18.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK43711.1 - 0.0032 16.9 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KKK43711.1 - 0.0033 17.3 1.3 0.006 16.5 0.3 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KKK43711.1 - 0.0062 15.8 0.5 0.035 13.3 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KKK43711.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.2 1 0 0 1 1 1 0 GMC oxidoreductase FAD_binding_3 PF01494.19 KKK43711.1 - 0.091 12.0 0.1 0.25 10.5 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain DUF4890 PF16231.5 KKK43711.1 - 0.29 11.6 1.6 0.44 11.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) Response_reg PF00072.24 KKK43712.1 - 8.8e-26 90.3 1.3 1e-25 90.1 1.3 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF5371 PF17341.2 KKK43712.1 - 0.045 13.9 0.6 0.54 10.5 0.0 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF5371) 3HCDH_RFF PF18321.1 KKK43712.1 - 0.067 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain RNase_H_2 PF13482.6 KKK43713.1 - 7.2e-18 65.1 1.4 8.2e-18 64.9 1.4 1.1 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo1 PF03104.19 KKK43713.1 - 2.8e-05 23.4 4.3 9.6e-05 21.7 4.3 1.8 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 KKK43713.1 - 0.0011 18.7 0.4 0.0015 18.2 0.4 1.3 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB AvrE_T3Es PF11725.8 KKK43715.1 - 0.14 9.4 0.0 0.17 9.1 0.0 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) F420_oxidored PF03807.17 KKK43716.1 - 1e-22 80.5 0.6 1.8e-22 79.8 0.1 1.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KKK43716.1 - 2.1e-07 31.3 0.2 3.9e-07 30.4 0.2 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KKK43716.1 - 0.00027 21.0 1.4 0.0066 16.4 1.4 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.9 KKK43716.1 - 0.00042 20.2 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain 3HCDH_N PF02737.18 KKK43716.1 - 0.0028 17.5 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK43716.1 - 0.0043 17.1 0.1 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KKK43716.1 - 0.0091 15.6 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KKK43716.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KKK43716.1 - 0.036 14.4 0.2 0.093 13.1 0.2 1.7 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KKK43716.1 - 0.063 14.1 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold LRR_8 PF13855.6 KKK43718.1 - 3e-08 33.3 9.2 0.0066 16.2 5.8 4.6 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KKK43718.1 - 5.3e-06 26.7 12.5 1.4 9.5 4.1 5.1 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) DUF1028 PF06267.12 KKK43720.1 - 0.0015 18.4 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF1028) ADH_zinc_N PF00107.26 KKK43721.1 - 2.1e-28 98.9 0.0 4.3e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK43721.1 - 4e-27 94.2 0.6 7.9e-27 93.3 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KKK43721.1 - 6.1e-11 42.2 0.0 1e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK43721.1 - 2.4e-07 31.9 0.0 3.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.13 KKK43721.1 - 2.2e-05 24.0 0.3 3.4e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AlaDh_PNT_C PF01262.21 KKK43721.1 - 0.0003 20.2 0.3 0.00047 19.5 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.7 KKK43721.1 - 0.00053 19.9 0.3 0.00096 19.1 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain CoA_binding PF02629.19 KKK43721.1 - 0.0018 18.9 0.2 0.0043 17.7 0.2 1.7 1 0 0 1 1 1 1 CoA binding domain Methyltransf_25 PF13649.6 KKK43721.1 - 0.0024 18.5 0.1 0.0051 17.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK43721.1 - 0.0057 17.4 0.1 0.016 16.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK43721.1 - 0.025 15.2 0.1 0.12 13.0 0.0 2.3 2 1 0 2 2 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KKK43721.1 - 0.047 13.5 0.2 0.079 12.8 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KKK43721.1 - 0.074 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TrkA_N PF02254.18 KKK43721.1 - 0.11 12.7 0.7 0.21 11.9 0.7 1.4 1 0 0 1 1 1 0 TrkA-N domain Ubie_methyltran PF01209.18 KKK43721.1 - 0.14 11.4 0.2 0.84 8.9 0.2 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsX PF02687.21 KKK43722.1 - 5.8e-16 58.8 23.1 1.8e-11 44.3 7.7 5.4 6 0 0 6 6 6 2 FtsX-like permease family PIRT PF15099.6 KKK43722.1 - 0.17 11.4 1.5 0.65 9.6 1.5 2.0 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family ABC_tran PF00005.27 KKK43723.1 - 2.9e-27 95.8 0.0 4.2e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK43723.1 - 4.4e-06 26.7 0.6 0.014 15.2 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK43723.1 - 7.8e-06 25.5 0.1 5.9e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KKK43723.1 - 0.00022 21.2 0.1 0.00037 20.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 KKK43723.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KKK43723.1 - 0.0027 16.8 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 KKK43723.1 - 0.0041 17.6 0.7 0.0059 17.1 0.5 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KKK43723.1 - 0.0046 16.9 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 KKK43723.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KKK43723.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KKK43723.1 - 0.013 15.9 0.1 0.016 15.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KKK43723.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KKK43723.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family ATPase_2 PF01637.18 KKK43723.1 - 0.023 14.6 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK43723.1 - 0.028 14.7 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK43723.1 - 0.04 14.2 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 KKK43723.1 - 0.05 12.4 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 KKK43723.1 - 0.057 12.6 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Roc PF08477.13 KKK43723.1 - 0.069 13.4 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KKK43723.1 - 0.071 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 KKK43723.1 - 0.082 12.5 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KKK43723.1 - 0.22 11.2 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Folate_carrier PF01770.18 KKK43724.1 - 0.038 12.7 4.5 0.041 12.6 4.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF4079 PF13301.6 KKK43724.1 - 6.8 6.8 10.3 15 5.8 1.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DeoC PF01791.9 KKK43725.1 - 4.5e-15 55.9 0.0 5.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF3905 PF13045.6 KKK43726.1 - 0.0036 17.3 0.0 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3905) Peptidase_M28 PF04389.17 KKK43727.1 - 5.1e-24 85.1 0.0 1.3e-21 77.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 CMV_US PF08001.11 KKK43727.1 - 0.0028 17.0 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 CMV US Lact_bio_phlase PF09508.10 KKK43727.1 - 0.056 11.9 0.0 0.57 8.5 0.0 2.1 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain DUF4910 PF16254.5 KKK43727.1 - 0.058 12.3 0.4 0.67 8.8 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4910) CPBP PF02517.16 KKK43728.1 - 2.7e-17 62.9 2.7 2.7e-17 62.9 2.7 6.2 3 1 0 3 3 3 2 CPBP intramembrane metalloprotease 12TM_1 PF09847.9 KKK43728.1 - 3.8e-10 39.4 84.2 3.8e-10 39.4 84.2 3.6 1 1 1 3 3 3 1 Membrane protein of 12 TMs ABC_tran PF00005.27 KKK43729.1 - 8.4e-30 104.1 0.0 2.3e-29 102.7 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KKK43729.1 - 1.8e-10 41.2 3.4 4.6e-05 23.4 0.4 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK43729.1 - 0.00087 19.8 3.1 0.0026 18.3 3.1 1.8 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KKK43729.1 - 0.0011 18.9 0.4 0.91 9.4 0.0 2.2 2 0 0 2 2 2 2 NTPase AAA_22 PF13401.6 KKK43729.1 - 0.0023 18.2 0.1 0.0064 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KKK43729.1 - 0.013 15.2 0.0 0.1 12.3 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 KKK43729.1 - 0.067 13.6 0.7 0.28 11.6 0.2 2.3 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CmcI PF04989.12 KKK43729.1 - 0.1 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase AAA_29 PF13555.6 KKK43729.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KKK43729.1 - 0.16 12.0 1.4 0.59 10.2 1.4 2.1 1 1 0 1 1 1 0 Helicase HerA, central domain Fer4 PF00037.27 KKK43730.1 - 4e-06 26.4 4.7 4e-06 26.4 4.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 KKK43730.1 - 4.3e-05 24.4 5.9 4.3e-05 24.4 5.9 2.1 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK43730.1 - 5e-05 23.8 5.2 0.00012 22.6 5.2 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43730.1 - 0.00014 21.9 1.1 0.00014 21.9 1.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43730.1 - 0.0048 16.9 4.1 0.0048 16.9 4.1 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain NinD PF17466.2 KKK43730.1 - 0.012 15.7 0.3 0.04 14.0 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function Gcd10p PF04189.13 KKK43730.1 - 0.014 14.5 0.1 0.018 14.1 0.1 1.1 1 0 0 1 1 1 0 Gcd10p family Fer4_10 PF13237.6 KKK43730.1 - 0.014 15.5 8.7 0.047 13.8 8.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK43730.1 - 0.026 15.1 2.3 0.026 15.1 2.3 2.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK43730.1 - 0.031 14.7 1.0 0.031 14.7 1.0 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK43730.1 - 0.11 13.5 5.3 0.11 13.5 5.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK43730.1 - 1.6 9.0 10.8 0.32 11.2 2.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 KKK43730.1 - 3.9 7.7 9.9 16 5.7 10.0 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain ABC_tran PF00005.27 KKK43731.1 - 1e-25 90.8 0.0 1.5e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK43731.1 - 1.3e-11 44.9 0.2 7.5e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKK43731.1 - 2.5e-06 27.4 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 KKK43731.1 - 2.3e-05 23.3 0.5 0.012 14.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KKK43731.1 - 0.0072 16.1 0.3 0.26 11.0 0.1 2.3 1 1 1 3 3 3 1 AAA domain AAA PF00004.29 KKK43731.1 - 0.011 16.2 0.4 0.14 12.6 0.4 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 KKK43731.1 - 0.032 13.7 0.5 3 7.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 KKK43731.1 - 0.092 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KKK43731.1 - 0.11 12.3 0.2 0.51 10.1 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KKK43731.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KKK43731.1 - 0.26 11.8 3.2 0.46 11.0 3.1 1.9 1 1 0 1 1 1 0 AAA domain FrhB_FdhB_C PF04432.13 KKK43732.1 - 2.8e-36 124.7 0.1 6.4e-36 123.5 0.1 1.6 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus DHODB_Fe-S_bind PF10418.9 KKK43732.1 - 5.4e-10 38.9 4.2 5.4e-10 38.9 4.2 2.4 2 0 0 2 2 2 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FrhB_FdhB_N PF04422.13 KKK43732.1 - 5.5e-09 36.0 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term NAD_binding_1 PF00175.21 KKK43732.1 - 0.00037 21.1 0.0 0.00093 19.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KKK43732.1 - 0.0059 16.9 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KKK43732.1 - 0.087 12.9 0.3 1.3 9.1 0.1 2.5 1 1 1 2 2 2 0 Ferric reductase NAD binding domain POR PF01558.18 KKK43733.1 - 3.1e-23 82.7 0.0 3.8e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 KKK43734.1 - 4e-34 117.6 0.0 6.1e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 KKK43735.1 - 7.9e-58 195.9 0.0 9.8e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KKK43735.1 - 3.3e-17 62.7 0.1 6.7e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KKK43735.1 - 1.7e-09 37.6 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain MTTB PF06253.11 KKK43736.1 - 1.6e-79 267.2 0.0 2.1e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Trimethylamine methyltransferase (MTTB) S-methyl_trans PF02574.16 KKK43737.1 - 1.2e-51 176.1 0.0 1.4e-51 175.9 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase B12-binding PF02310.19 KKK43738.1 - 1.9e-24 86.0 0.3 3e-24 85.4 0.3 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 KKK43738.1 - 6.2e-15 55.4 0.2 2.8e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 B12 binding domain tRNA-synt_His PF13393.6 KKK43739.1 - 1.6e-35 122.9 0.0 2e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KKK43739.1 - 1.1e-13 51.1 2.1 1.9e-13 50.4 2.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKK43739.1 - 1.4e-07 31.7 0.8 4.8e-07 29.9 0.8 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 KKK43739.1 - 0.00017 21.2 0.2 0.00093 18.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) EHD_N PF16880.5 KKK43739.1 - 0.026 14.4 0.1 0.073 13.0 0.1 1.8 1 0 0 1 1 1 0 N-terminal EH-domain containing protein LRR_8 PF13855.6 KKK43740.1 - 4.4e-22 77.6 51.9 1.5e-10 40.7 9.1 5.3 4 2 3 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 KKK43740.1 - 1.3e-19 70.0 37.0 2.5e-06 27.7 3.0 6.1 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) TIR_2 PF13676.6 KKK43740.1 - 5.3e-09 36.7 0.1 5.4e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 TIR domain LRR_1 PF00560.33 KKK43740.1 - 6.7e-05 22.9 30.9 0.14 12.8 1.8 8.4 7 1 1 8 8 8 3 Leucine Rich Repeat LRR_5 PF13306.6 KKK43740.1 - 0.00095 19.1 3.1 0.041 13.9 0.4 2.6 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DUF4062 PF13271.6 KKK43740.1 - 0.15 12.5 0.1 0.36 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Zip PF02535.22 KKK43741.1 - 3.1e-05 23.4 3.8 3.1e-05 23.4 3.8 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF1129 PF06570.11 KKK43741.1 - 1.4 8.3 17.3 0.33 10.4 1.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) Phospholamban PF04272.14 KKK43741.1 - 2.9 7.4 0.0 2.9 7.4 0.0 3.8 4 2 2 6 6 6 0 Phospholamban Glyco_transf_4 PF13439.6 KKK43742.1 - 0.033 14.2 0.0 0.33 10.9 0.0 2.6 2 2 0 2 2 2 0 Glycosyltransferase Family 4 NTP_transf_3 PF12804.7 KKK43744.1 - 1.2e-11 45.3 0.0 1.5e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KKK43744.1 - 0.00027 20.6 0.0 0.00093 18.8 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyl transferase Inos-1-P_synth PF01658.17 KKK43746.1 - 1.9e-33 114.9 0.1 4.4e-31 107.4 0.0 2.2 2 0 0 2 2 2 2 Myo-inositol-1-phosphate synthase MULE PF10551.9 KKK43749.1 - 0.00056 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 KKK43749.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 Transposase HTH_33 PF13592.6 KKK43749.1 - 0.011 15.4 0.2 0.66 9.7 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Transposase_mut PF00872.18 KKK43749.1 - 0.04 12.8 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family Ribosomal_L12_N PF16320.5 KKK43749.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain Mrr_N PF14338.6 KKK43749.1 - 0.18 12.0 0.1 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 Mrr N-terminal domain DNA_ligase_ZBD PF03119.16 KKK43749.1 - 0.24 11.5 4.4 3.3 7.8 4.4 2.4 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain PGM_PMM_I PF02878.16 KKK43750.1 - 3.1e-31 107.9 0.1 5.3e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KKK43750.1 - 9.2e-21 74.4 0.0 2.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KKK43750.1 - 6.2e-20 71.5 0.0 9.4e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ROK PF00480.20 KKK43751.1 - 1.9e-49 168.7 0.1 2.3e-49 168.5 0.1 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 KKK43751.1 - 5e-05 22.5 0.0 0.00018 20.6 0.0 1.7 2 0 0 2 2 2 1 Glucokinase FGGY_N PF00370.21 KKK43751.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Radical_SAM PF04055.21 KKK43752.1 - 1.8e-05 25.2 0.0 2.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily CbiA PF01656.23 KKK43752.1 - 0.0095 16.0 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ComFB PF10719.9 KKK43752.1 - 0.15 12.1 0.5 0.44 10.7 0.5 1.9 1 1 0 1 1 1 0 Late competence development protein ComFB ABC_membrane PF00664.23 KKK43753.1 - 4.5e-47 161.0 24.4 6.8e-47 160.4 24.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK43753.1 - 4.8e-32 111.3 0.0 9.2e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK43753.1 - 5.4e-06 26.4 1.0 0.08 12.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK43753.1 - 0.00011 21.7 0.4 0.0029 17.1 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK43753.1 - 0.00049 20.4 0.3 0.0054 17.0 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KKK43753.1 - 0.0018 18.8 0.5 0.0052 17.3 0.5 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 KKK43753.1 - 0.013 14.5 0.1 0.025 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.6 KKK43753.1 - 0.024 14.4 0.8 0.051 13.3 0.8 1.7 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KKK43753.1 - 0.041 13.9 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 KKK43753.1 - 0.045 13.8 0.3 0.12 12.4 0.3 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 KKK43753.1 - 0.068 12.9 4.1 0.099 12.3 2.3 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKK43753.1 - 0.085 12.6 0.2 0.21 11.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KKK43753.1 - 0.094 12.4 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KKK43753.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KKK43753.1 - 0.24 10.6 0.8 1.3 8.3 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin ABC_membrane PF00664.23 KKK43754.1 - 4.4e-39 134.8 22.7 5.9e-39 134.4 22.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KKK43754.1 - 5.1e-34 117.7 0.1 9.3e-34 116.9 0.1 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KKK43754.1 - 4.3e-05 23.1 1.6 0.0029 17.1 1.6 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 KKK43754.1 - 0.00019 20.7 0.4 0.00034 19.9 0.4 1.4 1 0 0 1 1 1 1 G-protein alpha subunit DUF87 PF01935.17 KKK43754.1 - 0.00096 19.3 0.7 0.0022 18.1 0.1 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 KKK43754.1 - 0.0039 16.5 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 KKK43754.1 - 0.0058 16.3 0.2 0.016 14.9 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KKK43754.1 - 0.019 14.7 0.7 0.031 14.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KKK43754.1 - 0.11 12.7 0.7 24 5.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain TrmB PF01978.19 KKK43755.1 - 7.2e-05 22.6 0.0 0.00018 21.3 0.0 1.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 KKK43755.1 - 0.00025 20.9 0.0 0.00044 20.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 KKK43755.1 - 0.077 13.2 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain ACDC PF14733.6 KKK43756.1 - 0.17 12.3 0.2 0.17 12.3 0.2 2.8 4 0 0 4 4 4 0 AP2-coincident C-terminal Surfac_D-trimer PF09006.11 KKK43757.1 - 0.0015 18.4 1.2 0.64 10.0 0.0 4.3 4 1 1 5 5 5 1 Lung surfactant protein D coiled-coil trimerisation Baculo_PEP_C PF04513.12 KKK43757.1 - 0.36 10.9 4.4 0.8 9.7 0.4 3.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 KKK43757.1 - 1.1 9.2 4.8 32 4.5 0.1 3.4 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DASH_Duo1 PF08651.10 KKK43757.1 - 1.2 9.0 8.9 2.5 8.0 0.2 4.7 3 2 2 5 5 5 0 DASH complex subunit Duo1 TolA_bind_tri PF16331.5 KKK43757.1 - 1.9 8.6 7.4 4.9 7.3 0.1 4.2 3 2 2 5 5 5 0 TolA binding protein trimerisation 60KD_IMP PF02096.20 KKK43757.1 - 7.9 6.3 9.0 28 4.6 0.3 3.5 1 1 2 3 3 3 0 60Kd inner membrane protein Mon1 PF03164.14 KKK43758.1 - 0.0076 15.4 0.1 0.01 15.0 0.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 zf-CHCC PF10276.9 KKK43761.1 - 0.025 14.6 0.4 0.061 13.4 0.4 1.7 1 0 0 1 1 1 0 Zinc-finger domain zf-C2HC_2 PF13913.6 KKK43761.1 - 0.067 13.1 0.1 0.067 13.1 0.1 2.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF1199 PF06712.11 KKK43761.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Vps51 PF08700.11 KKK43761.1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.0 2 1 0 2 2 2 0 Vps51/Vps67 Glutaredoxin PF00462.24 KKK43761.1 - 0.18 12.1 2.0 0.36 11.1 0.3 2.4 2 0 0 2 2 2 0 Glutaredoxin RNA_pol_Rpb1_5 PF04998.17 KKK43761.1 - 0.24 10.8 1.8 0.33 10.3 1.5 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4829 PF16111.5 KKK43761.1 - 0.52 11.1 6.0 0.23 12.3 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4829) Rad51 PF08423.11 KKK43762.1 - 1.2e-33 116.4 0.1 1.4e-33 116.2 0.1 1.0 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 KKK43762.1 - 1.5e-07 31.0 0.3 5.2e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 KaiC AAA PF00004.29 KKK43762.1 - 2.1e-05 25.0 0.1 4.9e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.21 KKK43762.1 - 3.3e-05 23.5 0.0 9.2e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 KKK43762.1 - 0.0023 17.7 0.1 0.085 12.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK43762.1 - 0.0074 16.2 3.5 0.012 15.5 3.5 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 KKK43762.1 - 0.031 14.0 0.2 0.36 10.6 0.0 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KKK43762.1 - 0.037 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KKK43762.1 - 0.051 13.0 0.2 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 KKK43762.1 - 0.15 12.1 1.2 0.41 10.7 1.1 1.9 1 1 0 1 1 1 0 AAA domain MAF_flag10 PF01973.18 KKK43763.1 - 3.3e-14 52.9 0.6 6.2e-14 52.0 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF115 GCV_H PF01597.19 KKK43764.1 - 5.4e-26 90.9 0.3 1.4e-25 89.5 0.3 1.6 1 1 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KKK43764.1 - 0.0092 15.8 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Phi29_Phage_SSB PF17427.2 KKK43764.1 - 0.062 13.5 0.0 0.078 13.2 0.0 1.1 1 0 0 1 1 1 0 Phage Single-stranded DNA-binding protein Disaggr_repeat PF06848.11 KKK43764.1 - 0.073 12.8 0.3 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Disaggregatase related repeat RnfC_N PF13375.6 KKK43764.1 - 0.16 12.0 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NAD_kinase PF01513.21 KKK43765.1 - 2.2e-34 119.0 0.0 2.5e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KKK43765.1 - 4.3e-05 23.1 0.0 0.00051 19.7 0.1 2.3 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DeoRC PF00455.22 KKK43765.1 - 0.0086 16.0 0.9 0.048 13.6 0.1 2.4 2 1 0 3 3 3 1 DeoR C terminal sensor domain OST3_OST6 PF04756.13 KKK43766.1 - 3.3e-10 39.8 5.1 4.2e-10 39.5 5.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Peptidase_M20 PF01546.28 KKK43767.1 - 1.5e-12 47.7 0.0 2.1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK43767.1 - 1.2e-07 31.7 0.1 3.3e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK43767.1 - 2.7e-06 27.2 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 KKK43767.1 - 6.2e-05 22.2 0.0 0.00024 20.2 0.0 2.0 2 1 0 2 2 2 1 M42 glutamyl aminopeptidase Prok-RING_1 PF14446.6 KKK43768.1 - 2e-05 24.4 5.8 5.2e-05 23.1 5.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 KKK43768.1 - 0.0012 18.7 3.5 0.0012 18.7 3.5 1.8 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KKK43768.1 - 0.0025 17.6 7.6 0.006 16.4 7.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_9 PF13901.6 KKK43768.1 - 0.0058 16.6 4.6 0.016 15.2 4.6 1.7 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon ADK_lid PF05191.14 KKK43768.1 - 0.0085 16.0 1.9 0.018 15.0 1.9 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zn_ribbon_17 PF17120.5 KKK43768.1 - 0.082 12.5 4.9 0.16 11.6 4.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-PHD-like PF15446.6 KKK43768.1 - 0.17 11.5 5.8 0.4 10.3 5.8 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 KKK43768.1 - 8.4 6.8 12.2 0.13 12.6 5.1 1.6 2 0 0 2 2 2 0 C1 domain Fer4 PF00037.27 KKK43769.1 - 3.1e-14 52.1 19.2 1.2e-07 31.3 6.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK43769.1 - 1e-11 44.3 17.3 1.1e-06 28.4 5.2 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK43769.1 - 5.5e-11 41.9 12.8 5.4e-07 29.3 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK43769.1 - 2.3e-10 40.5 14.6 2.7e-10 40.3 14.6 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK43769.1 - 3.6e-10 40.3 12.0 9.7e-05 22.9 0.8 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43769.1 - 8.4e-09 35.4 16.2 1.5e-08 34.7 16.3 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43769.1 - 1.7e-08 34.5 16.1 9.6e-08 32.1 16.1 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK43769.1 - 5.7e-07 29.6 19.3 0.0012 19.2 5.0 2.6 2 1 1 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK43769.1 - 7.2e-07 29.7 12.5 0.002 18.6 1.7 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43769.1 - 1.1e-06 29.5 14.3 0.00057 20.8 3.2 2.1 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 KKK43769.1 - 1.7e-05 25.3 16.0 2.9e-05 24.5 3.4 2.1 1 1 1 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KKK43769.1 - 2.1e-05 25.1 2.2 2.1e-05 25.1 2.2 2.5 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_8 PF13183.6 KKK43769.1 - 4.4e-05 23.8 17.6 0.0022 18.4 17.7 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK43769.1 - 8.3e-05 23.4 11.8 0.023 15.5 3.0 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK43769.1 - 0.00047 20.9 21.0 0.043 14.8 8.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain ETF_QO PF05187.13 KKK43769.1 - 0.19 11.9 7.6 0.14 12.3 2.0 1.9 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 KKK43769.1 - 0.79 9.9 14.5 1.8 8.8 3.0 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain SCIFF PF13165.6 KKK43769.1 - 1.3 9.0 11.3 4.3 7.4 2.4 2.2 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF Phage_holin_3_6 PF07332.11 KKK43770.1 - 0.002 18.1 2.8 0.0026 17.8 2.8 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DPM2 PF07297.12 KKK43770.1 - 0.28 11.5 10.7 0.57 10.5 10.7 1.5 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KKK43770.1 - 0.42 10.5 4.1 0.7 9.8 4.1 1.5 1 1 0 1 1 1 0 PIG-P DUF2207 PF09972.9 KKK43770.1 - 1.2 7.8 4.8 1.3 7.7 4.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2583 PF10762.9 KKK43770.1 - 1.9 9.0 6.2 1.5 9.3 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2583) DPM3 PF08285.11 KKK43770.1 - 3.4 7.9 6.3 5.2 7.3 6.3 1.5 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ABC2_membrane_2 PF12679.7 KKK43770.1 - 7.2 5.8 8.1 9.9 5.3 8.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PfkB PF00294.24 KKK43771.1 - 2.7e-60 204.2 0.0 3.1e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KKK43771.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase MannoseP_isomer PF01050.18 KKK43772.1 - 1.6e-07 31.4 0.4 6.6e-07 29.3 0.0 2.2 2 1 0 2 2 2 1 Mannose-6-phosphate isomerase Ribosomal_S19 PF00203.21 KKK43773.1 - 3.1e-30 103.9 0.2 5.9e-30 103.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 KKK43773.1 - 0.034 13.9 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Elongation factor P hydroxylase Ribosomal_L22 PF00237.19 KKK43774.1 - 1.3e-22 79.9 1.0 1.7e-22 79.6 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e XRN_N PF03159.18 KKK43774.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus EF-hand_12 PF17901.1 KKK43775.1 - 0.013 16.0 0.3 0.022 15.2 0.2 1.5 1 1 0 1 1 1 0 EF-hand fold domain Colicin_K PF17500.2 KKK43775.1 - 0.14 12.7 1.3 3.4 8.3 1.1 2.1 1 1 0 1 1 1 0 Colicin-K Ribosomal_S3_C PF00189.20 KKK43776.1 - 2.4e-16 60.0 2.4 4.4e-16 59.2 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KKK43776.1 - 3.6e-15 55.5 0.3 1.4e-14 53.7 0.1 2.1 2 0 0 2 2 2 1 KH domain KH_1 PF00013.29 KKK43776.1 - 0.0097 15.7 1.1 0.023 14.5 0.4 2.1 2 0 0 2 2 2 1 KH domain Ribosomal_L29 PF00831.23 KKK43777.1 - 9.6e-14 51.1 0.6 1.2e-13 50.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein NOP19 PF10863.8 KKK43777.1 - 0.082 12.7 0.0 0.089 12.6 0.0 1.0 1 0 0 1 1 1 0 Nucleolar protein 19 UPF0086 PF01868.16 KKK43778.1 - 5.9e-07 29.3 0.1 8.9e-07 28.7 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_S17 PF00366.20 KKK43779.1 - 1.4e-19 69.9 1.4 2.4e-19 69.2 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 KKK43779.1 - 0.0057 17.0 1.2 0.0067 16.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal PRF PF06875.11 KKK43779.1 - 0.041 13.3 0.1 0.061 12.7 0.1 1.1 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Ribosomal_L14 PF00238.19 KKK43780.1 - 7.6e-30 103.5 0.1 9.2e-30 103.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L26 PF16906.5 KKK43781.1 - 1.6e-19 70.1 0.1 2.2e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KKK43781.1 - 0.00018 21.3 0.1 0.00032 20.5 0.1 1.4 1 0 0 1 1 1 1 KOW motif ProQ_C PF17516.2 KKK43781.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 ProQ C-terminal domain Ribosomal_S4e PF00900.20 KKK43782.1 - 1.7e-25 88.7 0.3 3.4e-25 87.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 KKK43782.1 - 9.7e-10 38.4 2.7 1.8e-09 37.5 2.7 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KKK43782.1 - 7.1e-06 25.7 0.0 1.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KKK43782.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 KOW motif Ribosomal_L5 PF00281.19 KKK43783.1 - 1.5e-17 63.7 0.1 3.7e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 KKK43783.1 - 2e-16 59.9 0.1 3.9e-16 59.0 0.1 1.5 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_S14 PF00253.21 KKK43784.1 - 5.4e-07 29.3 5.7 5.8e-07 29.2 5.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e RNA_POL_M_15KD PF02150.16 KKK43784.1 - 0.069 13.0 1.1 5.3 7.0 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-RRN7 PF11781.8 KKK43784.1 - 1.3 8.8 12.8 1.2 8.9 1.9 2.2 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Thioredoxin PF00085.20 KKK43786.1 - 3e-17 62.5 0.0 3.6e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKK43786.1 - 0.00049 20.5 0.1 0.11 12.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KKK43786.1 - 0.0012 18.7 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin RelB_N PF18506.1 KKK43786.1 - 0.0042 16.9 0.3 0.0042 16.9 0.3 2.0 3 0 0 3 3 3 1 RelB Antitoxin alpha helical domain HyaE PF07449.11 KKK43786.1 - 0.0044 17.0 0.0 0.0061 16.5 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DUF836 PF05768.14 KKK43786.1 - 0.0045 17.4 0.0 0.0067 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.6 KKK43786.1 - 0.021 15.1 0.0 2.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Phosducin PF02114.16 KKK43786.1 - 0.027 13.4 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Phosducin Fer4_8 PF13183.6 KKK43787.1 - 7.3e-09 35.9 6.2 1.7e-08 34.8 6.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43787.1 - 1.6e-07 32.1 4.8 3.3e-07 31.2 4.8 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 KKK43787.1 - 2.5e-07 31.1 3.8 4.6e-07 30.3 3.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43787.1 - 3.8e-06 27.0 7.0 8.7e-06 25.8 7.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK43787.1 - 1.3e-05 25.7 5.6 3.1e-05 24.5 5.6 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43787.1 - 0.00023 21.2 11.5 0.008 16.3 12.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43787.1 - 0.0055 16.8 8.6 0.38 10.9 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK43787.1 - 0.012 15.8 2.8 0.41 10.9 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK43787.1 - 0.42 11.5 6.5 3.1 8.7 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK43787.1 - 2.4 8.1 16.4 4.8 7.2 3.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain TIM PF00121.18 KKK43788.1 - 2e-91 305.7 0.1 2.3e-91 305.5 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LMBR1 PF04791.16 KKK43789.1 - 0.11 11.3 0.6 0.15 11.0 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DALR_2 PF09190.11 KKK43789.1 - 0.14 12.7 0.7 0.31 11.5 0.1 1.8 2 0 0 2 2 2 0 DALR domain tRNA-synt_1 PF00133.22 KKK43790.1 - 4.3e-65 220.1 3.6 2.9e-43 148.0 6.9 6.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KKK43790.1 - 1.1e-63 214.2 0.1 2.1e-63 213.2 0.1 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KKK43790.1 - 5.4e-29 101.1 0.7 1.1e-20 73.8 0.0 4.9 4 2 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KKK43790.1 - 2.6e-18 66.4 7.5 8.2e-18 64.8 7.5 1.9 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA DZR PF12773.7 KKK43790.1 - 3.2e-05 23.9 9.8 0.14 12.2 0.0 3.3 3 0 0 3 3 3 3 Double zinc ribbon tRNA-synt_1e PF01406.19 KKK43790.1 - 0.00013 21.4 0.0 0.22 10.8 0.0 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 KKK43790.1 - 0.00045 19.2 0.0 0.76 8.6 0.0 3.2 4 0 0 4 4 4 2 tRNA synthetases class I (K) Mu-like_Com PF10122.9 KKK43790.1 - 0.014 14.8 10.4 0.13 11.7 0.2 3.7 4 0 0 4 4 4 0 Mu-like prophage protein Com UCH_1 PF13423.6 KKK43790.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Radical_SAM PF04055.21 KKK43791.1 - 1.2e-09 38.8 0.4 2.3e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily DUF2112 PF09885.9 KKK43791.1 - 0.036 14.1 0.3 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2112) BPL_LplA_LipB PF03099.19 KKK43792.1 - 1.1e-10 41.5 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Radical_SAM PF04055.21 KKK43793.1 - 7.7e-13 49.2 0.3 1.5e-12 48.2 0.3 1.5 1 0 0 1 1 1 1 Radical SAM superfamily PEP_hydrolase PF09370.10 KKK43793.1 - 0.064 12.5 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like PCP_red PF08369.10 KKK43793.1 - 0.072 13.3 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit F420_ligase PF01996.16 KKK43794.1 - 3.6e-60 203.4 1.0 5.2e-60 202.8 1.0 1.2 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Nitroreductase PF00881.24 KKK43794.1 - 3.1e-23 82.7 0.0 6.1e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK43794.1 - 7.4e-05 22.4 0.0 0.002 17.7 0.0 2.4 2 0 0 2 2 2 1 Putative TM nitroreductase DUF2624 PF11116.8 KKK43794.1 - 0.059 14.3 0.3 0.24 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) UPF0052 PF01933.18 KKK43795.1 - 3.1e-41 141.5 0.0 3.7e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DNA_pol_D_N PF18018.1 KKK43796.1 - 0.041 14.0 0.3 0.075 13.1 0.3 1.5 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain MDM10 PF12519.8 KKK43796.1 - 0.45 9.3 0.0 0.45 9.3 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 DUF2205 PF10224.9 KKK43796.1 - 0.87 9.6 6.4 2.5 8.2 1.6 2.6 2 1 0 2 2 2 0 Short coiled-coil protein DUF58 PF01882.18 KKK43797.1 - 7.8e-24 83.8 0.1 1.3e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 KKK43797.1 - 8.2e-09 36.1 0.0 1.8e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KKK43797.1 - 0.0011 18.4 0.0 0.006 16.0 0.0 2.0 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein TRAP_beta PF05753.14 KKK43797.1 - 0.0027 17.1 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) VWA PF00092.28 KKK43797.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain BatD PF13584.6 KKK43797.1 - 0.26 10.1 0.0 0.26 10.1 0.0 1.4 2 0 0 2 2 2 0 Oxygen tolerance AAA_lid_2 PF17863.1 KKK43798.1 - 3.3e-20 71.7 0.0 4.7e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 AAA lid domain ZT_dimer PF16916.5 KKK43800.1 - 1.7e-31 108.2 4.4 5.6e-10 39.2 0.0 3.1 3 0 0 3 3 3 3 Dimerisation domain of Zinc Transporter IKKbetaNEMObind PF12179.8 KKK43800.1 - 0.0075 16.3 0.2 5.5 7.1 0.1 2.4 2 0 0 2 2 2 2 I-kappa-kinase-beta NEMO binding domain DUF3160 PF11369.8 KKK43800.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Ldh_2 PF02615.14 KKK43801.1 - 2.4e-118 395.1 0.0 2.7e-118 394.9 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Ldh_2 PF02615.14 KKK43802.1 - 1.4e-117 392.6 0.0 1.5e-117 392.5 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Thioredoxin_3 PF13192.6 KKK43803.1 - 0.014 15.4 0.2 0.058 13.4 0.2 2.1 1 1 0 1 1 1 0 Thioredoxin domain zf-H2C2_2 PF13465.6 KKK43803.1 - 0.04 14.3 2.9 1.8 9.1 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C6H2 PF15801.5 KKK43803.1 - 0.16 12.3 0.2 0.16 12.3 0.2 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Di19 PF05605.12 KKK43803.1 - 0.17 12.2 1.9 12 6.2 0.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KKK43803.1 - 3.1 8.4 4.6 14 6.3 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type 7TM_GPCR_Srz PF10325.9 KKK43804.1 - 0.14 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz BEN PF10523.9 KKK43805.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 BEN domain Pur_DNA_glyco PF02245.16 KKK43807.1 - 3e-57 192.9 0.0 3.3e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) URO-D PF01208.17 KKK43808.1 - 9.6e-31 107.2 0.0 3.6e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) Inositol_P PF00459.25 KKK43809.1 - 3.7e-29 102.1 0.0 4.7e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 KKK43809.1 - 2.2e-05 24.0 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain ATP-synt_F PF01990.17 KKK43809.1 - 0.075 13.4 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit DDE_Tnp_1 PF01609.21 KKK43810.1 - 1.1e-10 41.6 0.9 2.4e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Transposase DDE domain SANT_DAMP1_like PF16282.5 KKK43810.1 - 0.028 14.6 0.1 0.12 12.5 0.1 2.1 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DDE_Tnp_1_6 PF13751.6 KKK43810.1 - 0.031 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain Pyr_redox_2 PF07992.14 KKK43811.1 - 1.1e-25 90.5 1.2 2.7e-25 89.2 1.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK43811.1 - 3.8e-12 46.1 3.2 3e-06 26.7 0.5 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK43811.1 - 7e-08 32.0 1.6 0.00023 20.4 0.2 2.7 2 1 0 3 3 3 2 FAD binding domain GIDA PF01134.22 KKK43811.1 - 0.0002 20.6 4.5 0.24 10.4 0.0 3.6 4 0 0 4 4 4 3 Glucose inhibited division protein A FAD_oxidored PF12831.7 KKK43811.1 - 0.00098 18.6 0.5 0.0085 15.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK43811.1 - 0.001 17.9 2.1 0.0032 16.2 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 KKK43811.1 - 0.0012 19.1 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK43811.1 - 0.0012 19.4 1.1 0.74 10.4 0.1 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK43811.1 - 0.0035 16.6 0.3 0.0072 15.6 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KKK43811.1 - 0.0057 15.9 0.0 0.015 14.6 0.0 1.7 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KKK43811.1 - 0.014 15.0 0.6 0.35 10.4 0.1 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase TetR_C_19 PF17924.1 KKK43811.1 - 0.56 10.8 3.6 0.71 10.5 2.1 1.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain H_PPase PF03030.16 KKK43812.1 - 2.1e-229 763.5 37.5 2.5e-229 763.3 37.5 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Cytochrom_B_C PF00032.17 KKK43812.1 - 0.11 12.8 0.3 0.11 12.8 0.3 3.6 4 0 0 4 4 4 0 Cytochrome b(C-terminal)/b6/petD SLATT_fungal PF18142.1 KKK43812.1 - 1.1 9.2 4.9 24 4.9 0.3 3.2 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain DUF1043 PF06295.12 KKK43812.1 - 2.6 8.0 4.9 19 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Aldo_ket_red PF00248.21 KKK43813.1 - 3.7e-53 180.6 2.0 1.3e-52 178.8 2.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family FAD_syn PF06574.12 KKK43813.1 - 0.066 13.1 0.4 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 FAD synthetase DUF2207 PF09972.9 KKK43814.1 - 0.00067 18.5 0.8 0.00071 18.5 0.8 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) S_4TM PF18159.1 KKK43814.1 - 0.035 13.4 2.1 0.04 13.2 2.1 1.0 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain zf-RRPl_C4 PF17026.5 KKK43814.1 - 0.038 14.1 2.4 0.048 13.8 2.4 1.1 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Herpes_US9 PF06072.11 KKK43814.1 - 0.11 12.4 0.4 0.16 11.9 0.4 1.4 1 1 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4191 PF13829.6 KKK43814.1 - 0.21 10.9 0.8 0.25 10.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2116 PF09889.9 KKK43814.1 - 1.3 9.1 8.0 13 5.8 8.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PALP PF00291.25 KKK43816.1 - 4.4e-05 23.1 0.0 7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CRISPR_Cas9_WED PF18061.1 KKK43816.1 - 0.18 11.9 6.0 0.78 9.8 0.2 2.5 2 1 0 2 2 2 0 CRISPR-Cas9 WED domain PPC PF04151.15 KKK43820.1 - 4.8e-28 98.1 27.9 5.3e-08 33.8 0.6 6.3 6 0 0 6 6 6 5 Bacterial pre-peptidase C-terminal domain Hydrolase_4 PF12146.8 KKK43821.1 - 1.9e-47 161.6 0.0 2.2e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK43821.1 - 9.1e-07 28.8 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK43821.1 - 1.1e-05 26.2 0.0 1.2e-05 26.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KKK43821.1 - 0.0094 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_8 PF06259.12 KKK43821.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DnaJ_C PF01556.18 KKK43822.1 - 1.3e-32 113.0 0.3 1.8e-32 112.5 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK43822.1 - 1.2e-26 92.6 1.4 2e-26 91.9 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KKK43822.1 - 2.1e-13 50.4 15.3 3.4e-13 49.7 15.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KKK43822.1 - 1.3e-08 34.7 12.2 8.3e-05 22.5 1.9 2.6 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein DUF1653 PF07866.11 KKK43822.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) A2L_zn_ribbon PF08792.10 KKK43822.1 - 0.88 9.4 5.8 1.5 8.7 0.3 3.0 3 0 0 3 3 3 0 A2L zinc ribbon domain ADH_N PF08240.12 KKK43823.1 - 8.8e-32 109.2 2.0 1.5e-31 108.5 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KKK43823.1 - 2.4e-24 85.8 0.0 3.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KKK43823.1 - 2.4e-07 31.9 0.0 4.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK43823.1 - 4.4e-06 26.3 0.0 6.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KKK43823.1 - 0.012 15.0 0.2 0.019 14.3 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KKK43823.1 - 0.026 14.8 0.1 0.042 14.1 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 KKK43823.1 - 0.043 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KKK43823.1 - 0.062 13.4 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 KKK43823.1 - 0.072 13.7 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TPR_3 PF07720.12 KKK43823.1 - 0.25 11.4 1.0 4.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat VWA_CoxE PF05762.14 KKK43824.1 - 3.8e-06 26.5 0.0 6.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2247 PF10004.9 KKK43824.1 - 0.032 14.0 0.2 0.06 13.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF1374 PF07118.11 KKK43824.1 - 0.65 10.5 5.4 26 5.4 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1374) NFACT-R_2 PF18297.1 KKK43828.1 - 3.7e-21 75.3 0.1 5.2e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_1 PF05670.13 KKK43828.1 - 0.003 18.2 0.0 0.0066 17.1 0.0 1.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain HATPase_c PF02518.26 KKK43829.1 - 3.2e-25 88.8 0.0 1.3e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KKK43829.1 - 1.3e-24 86.3 0.2 2.2e-06 27.9 0.1 4.3 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 KKK43829.1 - 6e-23 81.1 7.8 3.3e-06 27.3 0.2 5.3 5 0 0 5 5 5 4 PAS domain PAS PF00989.25 KKK43829.1 - 2.6e-18 66.1 0.2 1.2e-08 35.0 0.0 4.6 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 KKK43829.1 - 1.7e-17 63.0 0.0 3.3e-05 23.8 0.0 3.6 3 0 0 3 3 3 3 PAS domain HisKA PF00512.25 KKK43829.1 - 9.2e-11 41.6 0.2 3.1e-10 40.0 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KKK43829.1 - 0.00022 21.4 0.0 0.048 13.9 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 KKK43829.1 - 0.025 14.7 0.2 0.49 10.5 0.0 2.7 2 0 0 2 2 2 0 PAS domain HATPase_c_2 PF13581.6 KKK43829.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DsrD PF08679.11 KKK43829.1 - 1.8 8.9 4.4 0.99 9.7 0.7 2.5 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Acetyltransf_11 PF13720.6 KKK43830.1 - 0.02 15.4 0.9 0.022 15.2 0.9 1.1 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CDC45 PF02724.14 KKK43830.1 - 0.023 13.0 0.1 0.024 13.0 0.1 1.0 1 0 0 1 1 1 0 CDC45-like protein R-HINP1I PF11463.8 KKK43830.1 - 0.046 13.2 2.4 0.05 13.0 2.4 1.0 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease FAD_binding_4 PF01565.23 KKK43832.1 - 2.8e-28 98.4 0.0 8.1e-28 96.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 KKK43832.1 - 0.00023 20.9 0.0 0.00081 19.1 0.0 1.9 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain CCG PF02754.16 KKK43833.1 - 1.8e-27 95.4 6.8 4.1e-18 65.4 0.1 4.1 4 1 0 4 4 4 2 Cysteine-rich domain Fer4_8 PF13183.6 KKK43833.1 - 2.3e-10 40.8 4.3 1.1e-09 38.5 3.4 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK43833.1 - 3.4e-08 33.9 5.0 3.4e-08 33.9 5.0 3.3 4 0 0 4 4 3 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43833.1 - 3.6e-06 27.8 5.2 3.6e-06 27.8 5.2 2.3 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK43833.1 - 0.00014 22.4 12.0 0.00034 21.1 9.4 2.9 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43833.1 - 0.001 19.2 11.1 0.001 19.2 11.1 3.2 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK43833.1 - 0.0011 19.3 0.6 0.0011 19.3 0.6 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK43833.1 - 0.009 16.1 16.6 0.11 12.7 13.9 3.4 3 1 2 5 5 5 3 4Fe-4S dicluster domain Fer4 PF00037.27 KKK43833.1 - 0.026 14.4 1.7 0.026 14.4 1.7 3.6 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK43833.1 - 0.045 14.0 4.7 3.5 7.9 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43833.1 - 0.049 13.8 12.0 0.2 11.8 0.8 3.4 4 0 0 4 4 4 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43833.1 - 0.93 9.7 16.7 0.75 10.0 3.0 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK43833.1 - 7.7 7.1 9.8 19 5.9 1.1 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Rsbr_N PF08678.10 KKK43834.1 - 0.052 13.6 0.2 0.059 13.5 0.2 1.0 1 0 0 1 1 1 0 Rsbr N terminal HATPase_c PF02518.26 KKK43834.1 - 0.06 13.9 0.1 0.19 12.3 0.0 1.7 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KKK43835.1 - 2.7e-18 66.5 0.1 5.3e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK43835.1 - 2.9e-07 30.3 0.1 6.1e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KKK43835.1 - 0.0005 20.0 0.0 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HisKA PF00512.25 KKK43835.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ORMDL PF04061.14 KKK43835.1 - 0.6 9.9 6.2 5.2 6.9 0.2 2.4 2 0 0 2 2 2 0 ORMDL family CCG PF02754.16 KKK43836.1 - 0.035 14.3 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich domain PAS_3 PF08447.12 KKK43837.1 - 8.2e-25 86.9 1.3 2.3e-11 43.8 0.0 2.9 3 0 0 3 3 3 2 PAS fold HATPase_c PF02518.26 KKK43837.1 - 1.7e-23 83.2 0.3 7.4e-23 81.2 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KKK43837.1 - 8.9e-19 67.7 4.5 1.3e-09 38.2 0.3 3.5 3 0 0 3 3 3 2 PAS domain PAS_8 PF13188.7 KKK43837.1 - 1.5e-12 47.2 0.0 1.6e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 KKK43837.1 - 8.8e-12 44.9 0.1 2e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KKK43837.1 - 3.5e-11 43.1 0.3 2e-06 27.7 0.1 2.8 2 0 0 2 2 2 2 PAS fold PAS_12 PF18095.1 KKK43837.1 - 0.0026 17.4 1.2 1.9 8.1 0.0 3.2 2 1 1 3 3 3 2 UPF0242 C-terminal PAS-like domain HATPase_c_2 PF13581.6 KKK43837.1 - 0.005 16.8 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 KKK43837.1 - 0.015 15.2 0.0 0.015 15.2 0.0 3.5 4 0 0 4 4 4 0 GHKL domain PAS_4 PF08448.10 KKK43837.1 - 0.039 14.2 0.0 8.5 6.7 0.0 2.5 2 0 0 2 2 2 0 PAS fold PAS_11 PF14598.6 KKK43837.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain Annexin PF00191.20 KKK43837.1 - 0.17 12.0 2.5 3.1 7.9 0.1 3.1 3 0 0 3 3 2 0 Annexin Pox_A14 PF05767.12 KKK43837.1 - 0.55 10.4 4.5 0.4 10.9 0.8 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3810 PF12725.7 KKK43837.1 - 1.3 8.3 12.5 0.049 13.0 2.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) Voltage_CLC PF00654.20 KKK43837.1 - 6.1 6.0 6.2 29 3.8 6.4 1.8 1 1 0 1 1 1 0 Voltage gated chloride channel YdfA_immunity PF12127.8 KKK43838.1 - 0.052 12.6 0.3 0.076 12.1 0.3 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial Fer4_17 PF13534.6 KKK43839.1 - 5.6e-10 39.6 4.9 5.6e-10 39.6 4.9 1.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK43839.1 - 7.4e-10 39.1 5.2 1.2e-09 38.5 5.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43839.1 - 2.1e-08 34.1 4.2 3.9e-08 33.3 4.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43839.1 - 5.9e-08 32.8 6.0 2e-07 31.0 6.4 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK43839.1 - 6.9e-06 26.6 5.7 1.5e-05 25.5 5.7 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK43839.1 - 0.0004 20.5 4.7 0.00083 19.4 4.7 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43839.1 - 0.0013 18.7 10.5 0.0093 16.0 2.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK43839.1 - 0.0041 18.0 8.2 0.52 11.3 1.5 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 KKK43839.1 - 0.02 14.7 13.9 0.064 13.1 4.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK43839.1 - 0.023 15.2 3.6 0.023 15.2 3.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK43839.1 - 0.45 11.6 16.3 3.8 8.7 4.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KKK43839.1 - 1.3 9.3 11.9 0.12 12.5 1.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK43839.1 - 1.3 9.2 7.3 7.3 6.8 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain CCG PF02754.16 KKK43840.1 - 3.9e-36 123.1 0.6 7.8e-19 67.7 0.1 2.2 2 0 0 2 2 2 2 Cysteine-rich domain PA PF02225.22 KKK43840.1 - 0.057 13.5 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 PA domain Pyr_redox_2 PF07992.14 KKK43841.1 - 1.6e-12 47.3 0.0 3e-11 43.1 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.27 KKK43841.1 - 1.4e-08 34.2 25.1 4e-05 23.3 3.2 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain NAD_binding_8 PF13450.6 KKK43841.1 - 1.2e-07 31.8 0.0 3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK43841.1 - 2e-06 27.2 0.3 2.9e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KKK43841.1 - 3.4e-06 26.7 0.0 5.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_7 PF12838.7 KKK43841.1 - 1.7e-05 25.3 19.1 0.00023 21.7 12.6 3.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43841.1 - 3.2e-05 23.8 11.3 0.0006 19.8 2.5 3.8 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_15 PF13459.6 KKK43841.1 - 3.3e-05 24.5 7.5 0.014 16.1 1.4 2.7 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_16 PF13484.6 KKK43841.1 - 5.3e-05 24.1 7.0 0.15 13.0 0.4 3.5 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Pyr_redox PF00070.27 KKK43841.1 - 7.4e-05 23.2 0.1 0.00081 19.9 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_17 PF13534.6 KKK43841.1 - 7.6e-05 23.2 7.3 7.6e-05 23.2 7.3 2.9 3 0 0 3 3 2 1 4Fe-4S dicluster domain GIDA PF01134.22 KKK43841.1 - 0.00012 21.3 0.1 0.00029 20.1 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Fer4_8 PF13183.6 KKK43841.1 - 0.0004 20.8 14.1 0.00088 19.7 11.1 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain HI0933_like PF03486.14 KKK43841.1 - 0.00087 18.1 0.2 0.0017 17.1 0.2 1.5 1 1 0 1 1 1 1 HI0933-like protein Fer4_21 PF14697.6 KKK43841.1 - 0.0021 18.2 18.2 0.013 15.6 1.9 3.6 4 0 0 4 4 3 2 4Fe-4S dicluster domain DAO PF01266.24 KKK43841.1 - 0.0021 17.7 0.2 0.0035 17.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK43841.1 - 0.0031 16.8 0.1 0.0085 15.4 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KKK43841.1 - 0.0035 16.7 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KKK43841.1 - 0.0044 16.3 0.1 0.0069 15.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK43841.1 - 0.0063 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Fer4_9 PF13187.6 KKK43841.1 - 0.0063 16.7 12.7 0.0063 16.7 12.7 3.6 2 1 2 4 4 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43841.1 - 0.0072 16.4 17.0 0.014 15.5 6.1 3.7 4 0 0 4 4 3 2 4Fe-4S binding domain Trp_halogenase PF04820.14 KKK43841.1 - 0.01 14.7 0.7 2.5 6.8 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_13 PF13370.6 KKK43841.1 - 0.015 15.8 10.9 0.59 10.7 3.0 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 KKK43841.1 - 0.18 12.0 24.3 0.032 14.3 14.8 3.6 3 1 1 4 4 3 0 4Fe-4S dicluster domain TFIIB PF00382.19 KKK43843.1 - 4.1e-29 100.4 0.0 6.2e-19 67.8 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.23 KKK43843.1 - 9.8e-09 35.0 0.3 0.004 16.9 0.0 2.2 1 1 1 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.12 KKK43843.1 - 4.8e-06 26.0 1.1 9.8e-06 25.0 1.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KKK43843.1 - 7.6e-05 22.8 0.2 0.00053 20.0 0.1 2.0 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain A2L_zn_ribbon PF08792.10 KKK43843.1 - 0.0074 16.0 1.5 0.014 15.1 1.5 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain TFIIB_C_1 PF18542.1 KKK43843.1 - 0.015 15.3 0.4 0.05 13.6 0.3 1.8 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 Rrf2 PF02082.20 KKK43843.1 - 0.021 15.2 0.3 0.97 9.8 0.0 2.5 3 0 0 3 3 2 0 Transcriptional regulator DZR PF12773.7 KKK43843.1 - 0.025 14.6 0.2 0.047 13.7 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Cyclin_C PF02984.19 KKK43843.1 - 0.055 13.6 0.0 0.25 11.4 0.0 1.9 1 1 1 2 2 2 0 Cyclin, C-terminal domain Auto_anti-p27 PF06677.12 KKK43843.1 - 0.06 13.5 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HTH_9 PF08221.11 KKK43843.1 - 0.18 11.9 0.2 0.88 9.7 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Lar_restr_allev PF14354.6 KKK43843.1 - 0.35 11.3 2.0 0.53 10.7 0.2 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar DnaJ_C PF01556.18 KKK43844.1 - 6.4e-37 126.9 0.3 1e-36 126.2 0.3 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK43844.1 - 5.9e-27 93.6 3.4 5.9e-27 93.6 3.4 1.7 2 0 0 2 2 2 1 DnaJ domain HSP70 PF00012.20 KKK43845.1 - 2.4e-215 716.3 10.9 9.2e-213 707.7 10.9 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK43845.1 - 1.2e-13 50.6 3.7 3.6e-13 49.0 3.7 1.8 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 KKK43845.1 - 0.0035 17.7 7.2 0.065 13.7 0.3 3.8 3 2 0 3 3 3 1 Cell division protein FtsA DDR PF08841.10 KKK43845.1 - 0.012 14.7 0.2 0.022 13.7 0.2 1.4 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain TBCA PF02970.16 KKK43845.1 - 0.016 15.5 3.7 0.059 13.7 3.7 2.0 1 0 0 1 1 1 0 Tubulin binding cofactor A DUF2205 PF10224.9 KKK43845.1 - 0.081 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Short coiled-coil protein GrpE PF01025.19 KKK43847.1 - 1.6e-36 125.4 7.1 1.2e-35 122.7 7.1 1.9 1 1 0 1 1 1 1 GrpE DivIC PF04977.15 KKK43847.1 - 0.56 10.0 6.2 0.36 10.6 1.5 2.4 2 0 0 2 2 2 0 Septum formation initiator JAKMIP_CC3 PF16034.5 KKK43847.1 - 0.7 9.8 10.2 1.1 9.2 1.3 2.9 3 0 0 3 3 3 0 JAKMIP CC3 domain LRR_8 PF13855.6 KKK43848.1 - 5.1e-17 61.4 15.0 1.8e-11 43.6 4.8 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KKK43848.1 - 3.4e-13 49.5 21.1 3.9e-06 27.1 3.1 3.9 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK43848.1 - 4.9e-05 23.3 9.5 1.4 9.8 0.0 5.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KKK43848.1 - 0.00085 19.2 12.6 4 7.7 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 KKK43848.1 - 0.031 13.8 8.5 0.38 10.2 2.1 2.6 1 1 1 2 2 2 0 Leucine-rich repeat NosD PF05048.13 KKK43849.1 - 7.4e-36 123.6 77.5 6.9e-28 97.5 38.8 2.7 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK43849.1 - 5.9e-19 68.5 79.6 9.1e-13 48.4 27.2 3.7 2 1 1 4 4 4 3 Right handed beta helix region BNR PF02012.20 KKK43849.1 - 9.9 6.6 6.8 60 4.3 0.2 4.7 4 0 0 4 4 4 0 BNR/Asp-box repeat SecA_SW PF07516.13 KKK43853.1 - 0.027 14.5 0.6 0.034 14.2 0.6 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Tup_N PF08581.10 KKK43853.1 - 0.083 13.2 0.4 0.22 11.9 0.4 1.8 1 1 0 1 1 1 0 Tup N-terminal AbiTii PF18864.1 KKK43853.1 - 0.12 12.5 1.2 0.6 10.2 0.7 1.9 2 0 0 2 2 2 0 AbiTii CCG PF02754.16 KKK43855.1 - 6.3e-31 106.4 2.9 5.5e-17 61.8 0.7 2.2 2 0 0 2 2 2 2 Cysteine-rich domain Zn-C2H2_12 PF18112.1 KKK43855.1 - 0.023 15.2 1.5 0.026 15.0 0.0 1.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_4 PF14447.6 KKK43855.1 - 0.067 13.1 0.2 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Unstab_antitox PF09720.10 KKK43856.1 - 9e-15 54.5 0.2 1.2e-14 54.0 0.2 1.2 1 0 0 1 1 1 1 Putative addiction module component FliN_N PF16973.5 KKK43856.1 - 0.15 11.9 0.7 0.35 10.7 0.7 1.6 1 1 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal ParE_toxin PF05016.15 KKK43857.1 - 1.2e-07 32.2 0.0 1.5e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Glyco_trans_1_2 PF13524.6 KKK43857.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 PIN PF01850.21 KKK43858.1 - 4.5e-10 40.1 0.1 5.3e-10 39.9 0.1 1.1 1 0 0 1 1 1 1 PIN domain VAPB_antitox PF02697.14 KKK43859.1 - 9.9e-16 58.3 1.1 1.1e-15 58.1 1.1 1.0 1 0 0 1 1 1 1 Putative antitoxin SeqA_N PF17206.3 KKK43859.1 - 0.0079 15.5 0.9 0.024 14.0 0.9 1.8 1 1 0 1 1 1 1 SeqA protein N-terminal domain HTH_3 PF01381.22 KKK43860.1 - 6.7e-16 58.1 1.0 3.9e-15 55.7 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix HTH_19 PF12844.7 KKK43860.1 - 1.2e-08 34.8 0.2 1.1e-06 28.6 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 KKK43860.1 - 1.3e-06 28.7 0.0 3.9e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 KKK43860.1 - 0.0002 21.3 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain MerR PF00376.23 KKK43860.1 - 0.00044 19.9 0.1 0.022 14.5 0.0 2.8 2 1 0 2 2 2 1 MerR family regulatory protein HTH_Crp_2 PF13545.6 KKK43860.1 - 0.002 18.1 0.0 0.021 14.8 0.0 2.2 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KKK43860.1 - 0.0068 16.2 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 KKK43860.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 KKK43860.1 - 0.026 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 KKK43860.1 - 0.028 14.6 0.1 2.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 KKK43860.1 - 0.045 13.9 0.3 1.1 9.5 0.0 2.6 2 1 1 3 3 3 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 KKK43860.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain YdaS_antitoxin PF15943.5 KKK43860.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4 PF04545.16 KKK43860.1 - 0.11 12.0 0.2 5 6.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 MqsA_antitoxin PF15731.5 KKK43860.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA bPH_2 PF03703.14 KKK43861.1 - 2.2e-18 66.2 0.3 3.6e-18 65.5 0.3 1.3 1 0 0 1 1 1 1 Bacterial PH domain HTH_3 PF01381.22 KKK43861.1 - 4e-11 42.8 0.1 6.8e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KKK43861.1 - 1.2e-05 25.5 0.0 1.9e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 KKK43861.1 - 7.5e-05 23.1 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 KKK43861.1 - 0.00014 21.3 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 KKK43861.1 - 0.0037 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain bPH_4 PF06713.11 KKK43861.1 - 0.013 15.6 0.4 0.032 14.3 0.4 1.7 1 0 0 1 1 1 0 Bacterial PH domain YdaS_antitoxin PF15943.5 KKK43861.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT bPH_5 PF10882.8 KKK43861.1 - 0.044 13.9 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial PH domain HTH_AsnC-type PF13404.6 KKK43861.1 - 0.06 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF2207 PF09972.9 KKK43861.1 - 0.5 9.1 6.0 0.69 8.6 6.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 KKK43861.1 - 5.6 7.0 5.5 2.8 8.0 2.5 1.9 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FliL PF03748.14 KKK43862.1 - 0.036 14.6 0.5 7.4 7.2 0.1 2.2 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL NdhM PF10664.9 KKK43862.1 - 0.12 12.7 0.2 2.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M DUF362 PF04015.12 KKK43863.1 - 9.2e-30 104.4 0.1 1.6e-29 103.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF362) URO-D PF01208.17 KKK43864.1 - 1.8e-20 73.4 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) CoA_trans PF01144.23 KKK43865.1 - 2.5e-07 30.3 0.0 4.7e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 KKK43866.1 - 6.4e-20 71.5 0.1 8.1e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 Coenzyme A transferase Peptidase_MA_2 PF13485.6 KKK43866.1 - 0.079 12.6 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily CitF PF04223.12 KKK43866.1 - 0.096 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) HATPase_c PF02518.26 KKK43867.1 - 1.8e-21 76.7 3.1 2.2e-21 76.4 0.2 2.5 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK43867.1 - 4.7e-13 49.0 0.1 1e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KKK43867.1 - 6e-10 39.3 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KKK43867.1 - 1.7e-07 31.4 0.1 5.1e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 KKK43867.1 - 1.5e-06 28.1 0.0 3.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KKK43867.1 - 9e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 KKK43867.1 - 0.0024 17.7 0.2 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK43867.1 - 0.022 14.7 3.9 0.083 12.8 2.4 2.7 1 1 1 2 2 2 0 GHKL domain ArlS_N PF18719.1 KKK43867.1 - 1 9.6 6.7 0.8 9.9 0.6 2.5 2 0 0 2 2 2 0 ArlS sensor domain ATP-synt_8 PF00895.20 KKK43867.1 - 1.6 9.2 11.7 6.6 7.3 2.8 3.2 2 1 0 2 2 2 0 ATP synthase protein 8 Oxidored_FMN PF00724.20 KKK43868.1 - 4.9e-67 226.6 0.0 8.8e-67 225.8 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 KKK43868.1 - 4.1e-05 23.2 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein HMGL-like PF00682.19 KKK43868.1 - 0.029 13.9 0.0 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 HMGL-like Dus PF01207.17 KKK43868.1 - 0.059 12.5 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Sulfatase PF00884.23 KKK43869.1 - 2.7e-84 283.2 0.1 3.2e-84 282.9 0.1 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK43869.1 - 0.00055 19.6 1.2 0.12 11.9 0.1 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KKK43870.1 - 0.00035 20.4 0.2 0.00051 19.9 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 KKK43870.1 - 0.0041 17.3 0.5 0.0055 16.9 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) PTPA PF03095.15 KKK43870.1 - 0.16 11.4 0.4 0.16 11.4 0.0 1.3 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF4332 PF14229.6 KKK43872.1 - 1.4e-17 64.1 0.0 3.2e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) Peptidase_M36 PF02128.15 KKK43872.1 - 0.0085 15.3 0.0 0.02 14.1 0.0 1.5 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) HHH_5 PF14520.6 KKK43872.1 - 0.0087 16.6 0.0 0.022 15.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.8 KKK43872.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus Peptidase_M4 PF01447.18 KKK43872.1 - 0.044 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain Reprolysin_4 PF13583.6 KKK43872.1 - 0.17 11.5 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Radical_SAM PF04055.21 KKK43873.1 - 3.4e-09 37.3 0.1 7.2e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 KKK43873.1 - 6.5e-06 26.3 0.2 1.6e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK43873.1 - 1.1e-05 25.8 0.0 2.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain TerC PF03741.16 KKK43874.1 - 0.14 11.8 5.6 0.15 11.7 5.6 1.1 1 0 0 1 1 1 0 Integral membrane protein TerC family DUF4191 PF13829.6 KKK43874.1 - 0.63 9.3 1.7 0.61 9.4 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2070 PF09843.9 KKK43874.1 - 1.5 7.0 7.8 1.5 7.0 7.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Lectin_N PF03954.14 KKK43874.1 - 1.6 8.4 3.7 2.1 8.1 0.9 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Glyoxalase PF00903.25 KKK43875.1 - 2.9e-12 46.9 0.0 1e-11 45.1 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKK43875.1 - 2.5e-06 27.7 0.0 4.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KKK43875.1 - 0.0083 16.0 0.1 1.9 8.5 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KKK43875.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain UBA_5 PF16577.5 KKK43875.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 UBA domain CMD PF02627.20 KKK43876.1 - 0.17 12.0 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DUF4976 PF16347.5 KKK43877.1 - 0.0001 22.5 0.1 0.00011 22.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Spore_II_R PF09551.10 KKK43879.1 - 3 8.3 7.2 0.42 11.1 1.0 2.3 1 1 2 3 3 3 0 Stage II sporulation protein R (spore_II_R) DUF4976 PF16347.5 KKK43880.1 - 0.00012 22.3 0.2 0.00016 21.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Amidohydro_2 PF04909.14 KKK43881.1 - 8.9e-33 114.3 0.0 2.7e-32 112.7 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KKK43881.1 - 0.0085 15.5 0.0 0.051 13.0 0.0 2.3 1 1 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 KKK43881.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase family Alkyl_sulf_dimr PF14863.6 KKK43882.1 - 6.5e-21 75.2 0.0 1.1e-20 74.6 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KKK43882.1 - 1.3e-17 64.4 0.0 2.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK43882.1 - 0.00052 19.6 0.0 0.00085 18.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain YfdX PF10938.8 KKK43882.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 YfdX protein Fer4_2 PF12797.7 KKK43884.1 - 0.026 14.6 3.0 0.055 13.6 3.0 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_9 PF13187.6 KKK43884.1 - 0.042 14.0 2.9 0.098 12.8 2.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK43884.1 - 0.11 13.1 4.6 0.074 13.7 2.6 1.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43884.1 - 0.29 11.3 3.3 0.67 10.1 3.3 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain adh_short PF00106.25 KKK43885.1 - 4.6e-37 127.4 0.1 5.2e-36 124.0 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK43885.1 - 1.4e-26 93.5 0.0 9.3e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK43885.1 - 4.7e-11 42.9 0.0 7.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK43885.1 - 8.7e-05 22.1 0.0 0.00036 20.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK43885.1 - 0.00021 21.2 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding LDcluster4 PF18306.1 KKK43885.1 - 0.0097 15.5 0.2 0.015 14.9 0.2 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Eno-Rase_NADH_b PF12242.8 KKK43885.1 - 0.021 14.6 0.1 0.048 13.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.16 KKK43885.1 - 0.034 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Toprim_3 PF13362.6 KKK43885.1 - 0.036 14.4 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 Toprim domain GDP_Man_Dehyd PF16363.5 KKK43885.1 - 0.055 12.9 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ABC_sub_bind PF04392.12 KKK43885.1 - 0.073 12.3 0.2 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein Hexapep_2 PF14602.6 KKK43885.1 - 0.54 10.0 2.3 0.66 9.8 1.1 1.7 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Claudin_2 PF13903.6 KKK43886.1 - 0.08 12.7 5.2 0.1 12.3 1.0 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DsbD PF02683.15 KKK43887.1 - 2.2e-20 73.5 20.4 3.3e-20 72.9 20.4 1.2 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 KKK43887.1 - 4.4e-09 36.6 14.9 8.2e-09 35.7 14.9 1.4 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region AhpC-TSA PF00578.21 KKK43888.1 - 6.8e-11 42.2 0.0 9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KKK43888.1 - 3.1e-08 33.8 0.0 4.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like SCO1-SenC PF02630.14 KKK43888.1 - 6.8e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 1 0 1 1 1 1 SCO1/SenC Redoxin PF08534.10 KKK43888.1 - 0.0058 16.3 0.0 0.0075 16.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 KKK43888.1 - 0.018 15.0 0.0 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 KKK43888.1 - 0.025 15.0 0.0 0.075 13.5 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain DUF2583 PF10762.9 KKK43888.1 - 0.15 12.5 0.1 0.22 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) TraF PF13728.6 KKK43888.1 - 0.2 11.5 0.0 0.5 10.2 0.0 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein Big_5 PF13205.6 KKK43888.1 - 0.47 11.2 2.0 4.1 8.1 0.5 2.5 2 1 0 2 2 2 0 Bacterial Ig-like domain TM1586_NiRdase PF14512.6 KKK43890.1 - 1e-08 35.1 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 KKK43890.1 - 0.0058 16.7 0.0 0.027 14.5 0.0 1.9 1 1 1 2 2 2 1 Nitroreductase family COesterase PF00135.28 KKK43894.1 - 8.3e-118 394.4 0.0 9.5e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KKK43894.1 - 5.7e-11 42.7 0.2 3.9e-10 40.0 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK43894.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family LSM PF01423.22 KKK43895.1 - 2.1e-14 52.9 0.3 2.8e-14 52.6 0.3 1.2 1 0 0 1 1 1 1 LSM domain Clenterotox PF03505.14 KKK43895.1 - 0.088 12.4 0.1 0.096 12.3 0.1 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin Ribosomal_L37e PF01907.19 KKK43896.1 - 3.1e-18 65.6 13.4 3.1e-18 65.6 13.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.7 KKK43896.1 - 0.0031 17.5 2.6 0.0042 17.1 2.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK43896.1 - 0.0077 15.6 1.2 0.013 14.9 1.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK43896.1 - 0.015 16.1 2.6 0.019 15.7 2.6 1.2 1 0 0 1 1 1 0 zinc-ribbon family DUF35_N PF12172.8 KKK43896.1 - 0.053 13.4 7.1 0.076 12.9 7.1 1.2 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) OrfB_Zn_ribbon PF07282.11 KKK43896.1 - 0.14 12.1 4.2 0.2 11.6 4.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L32p PF01783.23 KKK43896.1 - 0.32 11.3 9.2 0.13 12.5 5.8 2.0 1 1 1 2 2 2 0 Ribosomal L32p protein family zinc_ribbon_2 PF13240.6 KKK43896.1 - 1.1 9.1 6.1 9.1 6.2 1.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rrf2 PF02082.20 KKK43900.1 - 5.2e-22 78.0 0.1 6.8e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 KKK43900.1 - 7.8e-05 22.2 0.1 0.00019 21.0 0.1 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding PALP PF00291.25 KKK43901.1 - 2.6e-57 194.5 0.0 2.9e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lactamase_B PF00753.27 KKK43905.1 - 1.1e-16 61.4 0.0 1.9e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK43905.1 - 3.1e-10 39.9 0.1 4.8e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK43905.1 - 0.0049 16.8 0.1 0.0082 16.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KKK43905.1 - 0.081 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK43906.1 - 7.6e-15 55.4 0.0 1.9e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK43906.1 - 2.1e-11 43.7 0.0 2.5e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UvrB_inter PF17757.1 KKK43906.1 - 0.02 15.1 0.1 5.3 7.3 0.0 3.0 3 0 0 3 3 3 0 UvrB interaction domain MaoC_dehydratas PF01575.19 KKK43907.1 - 1e-27 96.2 0.0 1.8e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK43907.1 - 3.7e-06 27.1 0.0 0.001 19.2 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KKK43908.1 - 7.7e-28 96.5 0.0 1.2e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK43908.1 - 0.0011 19.1 0.0 0.015 15.4 0.0 2.3 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KKK43909.1 - 2.8e-28 98.0 0.0 4.9e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK43909.1 - 1.5e-08 34.9 0.0 9.2e-07 29.1 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Polbeta PF18765.1 KKK43910.1 - 1.6e-10 40.9 0.3 2.3e-10 40.4 0.3 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK43910.1 - 1.4e-09 38.1 0.5 1.9e-09 37.7 0.5 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain Beta_lactamase3 PF17030.5 KKK43910.1 - 0.021 14.1 0.3 0.026 13.8 0.3 1.1 1 0 0 1 1 1 0 Putative beta-lactamase-like family DUF86 PF01934.17 KKK43911.1 - 1.2e-18 67.0 1.3 1.5e-18 66.8 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF86 NTase_sub_bind PF08780.11 KKK43911.1 - 0.015 15.3 0.1 0.017 15.0 0.1 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like DUF4145 PF13643.6 KKK43911.1 - 0.047 13.8 0.2 0.084 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) DUF4047 PF13256.6 KKK43911.1 - 0.052 13.7 0.2 0.12 12.6 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Fer4 PF00037.27 KKK43912.1 - 6.3e-12 44.8 15.3 6.4e-07 28.9 3.6 2.6 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK43912.1 - 3.8e-10 39.7 10.5 3.8e-10 39.7 10.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43912.1 - 1e-09 38.0 12.7 0.00013 21.9 2.0 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK43912.1 - 3.7e-09 37.0 20.4 1.4e-06 28.8 11.3 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43912.1 - 8.6e-08 32.2 11.0 8.6e-08 32.2 11.0 2.3 1 1 2 3 3 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43912.1 - 7.6e-06 25.7 11.0 0.00072 19.5 1.9 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK43912.1 - 8.9e-06 26.6 17.2 0.00073 20.4 0.7 3.1 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK43912.1 - 1e-05 25.6 11.5 1e-05 25.6 11.5 2.4 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK43912.1 - 9.8e-05 23.0 1.8 9.8e-05 23.0 1.8 3.0 2 1 1 3 3 2 2 4Fe-4S single cluster domain Fer4_22 PF17179.4 KKK43912.1 - 0.00054 20.7 5.3 0.021 15.7 0.3 3.4 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK43912.1 - 0.0032 18.0 21.3 0.029 14.9 1.7 3.3 2 1 3 5 5 5 4 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK43912.1 - 0.0076 16.7 1.1 0.0076 16.7 1.1 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK43912.1 - 0.057 13.9 23.1 0.55 10.7 2.6 3.2 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK43915.1 - 2e-08 34.0 15.3 8.9e-05 22.4 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 KKK43915.1 - 2.4e-08 33.5 17.9 3.8e-05 23.3 3.3 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK43915.1 - 5.8e-07 29.5 13.3 1.1e-06 28.7 13.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK43915.1 - 2.9e-06 27.0 12.0 0.0019 18.2 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK43915.1 - 4.9e-06 27.0 7.8 1.1e-05 25.9 7.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK43915.1 - 5.8e-05 23.1 10.7 0.0061 16.6 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK43915.1 - 0.00028 21.0 11.4 0.00054 20.1 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK43915.1 - 0.0027 18.6 11.0 0.01 16.8 3.7 2.5 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK43915.1 - 0.003 17.9 14.7 0.015 15.8 3.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK43915.1 - 0.0033 17.9 5.1 0.63 10.5 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK43915.1 - 2.1 9.0 12.0 3.4 8.3 3.2 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain RHH_1 PF01402.21 KKK43916.1 - 3e-05 23.8 0.0 6.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_8 PF17723.1 KKK43916.1 - 0.0013 18.9 0.1 0.0013 18.9 0.1 1.1 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family HMG_CoA_synt_N PF01154.17 KKK43918.1 - 3e-21 76.0 0.0 5.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 KKK43918.1 - 1.7e-08 34.4 0.0 4.8e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Thiolase_N PF00108.23 KKK43918.1 - 0.00021 20.8 0.1 0.00035 20.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KKK43918.1 - 0.0004 20.2 0.0 0.00088 19.1 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LIAS_N PF16881.5 KKK43918.1 - 0.02 15.3 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family DNA_pol3_theta PF06440.11 KKK43922.1 - 0.053 13.2 0.1 0.097 12.3 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit HMG-CoA_red PF00368.18 KKK43924.1 - 1.5e-107 359.8 2.8 1.8e-107 359.5 2.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase UbiD PF01977.16 KKK43925.1 - 2.3e-97 326.4 0.0 2.8e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase LIM PF00412.22 KKK43926.1 - 0.0038 17.4 3.1 0.0038 17.4 3.1 1.9 2 0 0 2 2 2 1 LIM domain zf-C3HC4_3 PF13920.6 KKK43926.1 - 0.018 14.9 1.4 0.018 14.9 1.4 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4428 PF14471.6 KKK43926.1 - 0.14 12.1 5.1 0.34 10.9 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DWNN PF08783.11 KKK43929.1 - 0.017 15.4 0.2 0.018 15.3 0.2 1.1 1 0 0 1 1 1 0 DWNN domain ParBc PF02195.18 KKK43930.1 - 0.0011 19.2 0.1 0.0024 18.1 0.1 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain DUF521 PF04412.13 KKK43932.1 - 1.7e-152 507.8 0.2 1.9e-152 507.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 KKK43933.1 - 2.5e-35 120.1 0.5 2.5e-35 120.1 0.5 1.5 2 0 0 2 2 2 1 Aconitase X swivel domain PEP-utilizers PF00391.23 KKK43933.1 - 0.016 15.0 1.3 0.15 11.8 0.5 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain GHMP_kinases_C PF08544.13 KKK43934.1 - 2.2e-14 53.6 0.1 5.9e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KKK43934.1 - 1.6e-12 47.5 0.5 3.1e-12 46.5 0.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Peptidase_C23 PF05379.11 KKK43934.1 - 0.032 14.4 0.2 7 6.8 0.0 2.9 2 0 0 2 2 2 0 Carlavirus endopeptidase AA_kinase PF00696.28 KKK43935.1 - 5.3e-32 111.3 0.1 6.1e-32 111.1 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family PIN_11 PF18479.1 KKK43935.1 - 0.075 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 PIN like domain YAcAr PF10686.9 KKK43935.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family FMN_dh PF01070.18 KKK43936.1 - 1e-17 64.2 0.0 3.8e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KKK43936.1 - 9.7e-06 24.9 0.0 0.00045 19.5 0.0 2.3 2 0 0 2 2 2 2 Conserved region in glutamate synthase IMPDH PF00478.25 KKK43936.1 - 0.0041 16.2 0.0 0.12 11.3 0.0 2.8 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KKK43936.1 - 0.0084 15.3 1.4 0.035 13.3 1.3 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase SAM_Exu PF18609.1 KKK43936.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Exuperantia SAM-like domain Mon1 PF03164.14 KKK43937.1 - 2.6e-05 23.5 0.5 3.2e-05 23.2 0.5 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Flavoprotein PF02441.19 KKK43938.1 - 8.1e-27 93.9 0.6 1e-26 93.6 0.6 1.0 1 0 0 1 1 1 1 Flavoprotein polyprenyl_synt PF00348.17 KKK43939.1 - 1.9e-54 184.5 0.0 2.5e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase TMCCDC2 PF15844.5 KKK43939.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Hydrolase_4 PF12146.8 KKK43940.1 - 4.1e-09 36.1 0.2 8.2e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK43940.1 - 5e-08 32.9 0.0 8.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK43940.1 - 2.2e-06 28.4 0.0 4.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KKK43940.1 - 8.4e-06 25.8 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KKK43940.1 - 2.7e-05 23.9 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KKK43940.1 - 3.4e-05 23.5 0.0 0.0018 17.9 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 KKK43940.1 - 0.009 15.6 1.2 0.18 11.3 0.0 2.8 2 1 0 2 2 2 1 Lipid-droplet associated hydrolase DUF1100 PF06500.11 KKK43940.1 - 0.012 14.5 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.20 KKK43940.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KKK43940.1 - 0.062 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) Response_reg PF00072.24 KKK43941.1 - 9.4e-21 74.1 0.0 1.1e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF4868 PF16162.5 KKK43941.1 - 0.013 15.4 0.2 0.016 15.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) Glyco_hydro_38N PF01074.22 KKK43942.1 - 1.6e-29 103.2 0.0 4.1e-29 101.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KKK43942.1 - 3.4e-18 66.5 0.0 8.1e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KKK43942.1 - 4.5e-10 39.5 0.0 1e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KKK43942.1 - 4e-07 30.1 0.2 1.6e-06 28.1 0.2 2.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain TPR_12 PF13424.6 KKK43944.1 - 1.8e-28 98.6 1.0 4.6e-10 39.6 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK43944.1 - 2.2e-18 65.2 14.8 1.2e-05 24.9 0.3 5.8 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KKK43944.1 - 2.3e-15 55.9 2.5 0.0029 17.4 0.0 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK43944.1 - 2.8e-15 55.1 15.0 0.00011 22.0 0.1 6.0 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK43944.1 - 8.8e-14 50.4 4.7 0.00063 19.6 0.0 5.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK43944.1 - 1.7e-11 44.1 0.1 6.9e-06 25.7 0.2 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 KKK43944.1 - 3.9e-09 36.0 18.3 0.0013 18.8 0.3 6.2 5 1 0 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.6 KKK43944.1 - 1.3e-08 34.7 0.8 0.0005 19.6 0.9 2.2 1 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP SIR2_2 PF13289.6 KKK43944.1 - 5.4e-08 33.1 0.1 1.8e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 SIR2-like domain SHNi-TPR PF10516.9 KKK43944.1 - 2.3e-07 30.1 7.5 0.0065 15.9 0.1 5.2 5 0 0 5 5 5 2 SHNi-TPR TPR_11 PF13414.6 KKK43944.1 - 4e-07 29.6 3.4 0.0058 16.3 0.1 4.4 3 1 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 KKK43944.1 - 0.00043 20.9 0.1 2.3 8.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK43944.1 - 0.0023 18.5 0.4 28 5.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK43944.1 - 0.03 15.1 1.1 24 6.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 KKK43944.1 - 0.084 12.9 1.2 16 5.5 0.3 3.3 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) NYD-SP28_assoc PF14775.6 KKK43944.1 - 0.21 11.7 3.8 12 6.1 0.0 3.6 4 0 0 4 4 4 0 Sperm tail C-terminal domain MIT PF04212.18 KKK43944.1 - 0.61 10.2 5.4 29 4.8 0.1 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF43 PF01861.16 KKK43945.1 - 1.5e-44 152.1 0.0 2.9e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain AdoMet_dc PF02675.15 KKK43945.1 - 4.1e-25 88.1 0.0 7.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase N6-adenineMlase PF10237.9 KKK43945.1 - 4e-05 23.5 0.0 7.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase HTH_24 PF13412.6 KKK43945.1 - 0.00037 20.0 0.1 0.0009 18.8 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Cons_hypoth95 PF03602.15 KKK43945.1 - 0.00048 19.8 0.0 0.00082 19.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Spermine_synth PF01564.17 KKK43945.1 - 0.001 18.5 0.5 0.0022 17.5 0.1 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase domain MTS PF05175.14 KKK43945.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AAA_31 PF13614.6 KKK43945.1 - 0.083 12.8 0.2 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Methyltr_RsmB-F PF01189.17 KKK43945.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_12 PF08242.12 KKK43945.1 - 0.15 12.8 0.0 0.39 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FMN_red PF03358.15 KKK43948.1 - 2.3e-28 98.9 0.0 2.9e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KKK43948.1 - 8.7e-17 61.5 0.0 1.1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KKK43948.1 - 0.091 13.0 0.0 0.37 11.0 0.0 1.8 1 1 1 2 2 2 0 Flavodoxin SH3_2 PF07653.17 KKK43948.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain HTH_34 PF13601.6 KKK43949.1 - 1.1e-07 31.9 0.0 1.3e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF5013 PF16405.5 KKK43950.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5013) AMP-binding PF00501.28 KKK43952.1 - 3.2e-78 263.2 0.0 3.9e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK43952.1 - 1.5e-20 73.9 0.1 3e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2011 PF09428.10 KKK43952.1 - 0.15 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) HATPase_c PF02518.26 KKK43953.1 - 1.7e-12 47.8 0.4 3.8e-12 46.7 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mhr1 PF12829.7 KKK43953.1 - 0.053 13.6 0.2 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination C_GCAxxG_C_C PF09719.10 KKK43955.1 - 2.3e-12 47.2 0.0 3.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) EcKinase PF02958.20 KKK43956.1 - 2.2e-23 83.0 0.4 2.4e-13 50.1 0.0 2.5 2 1 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 KKK43956.1 - 4.2e-11 43.2 0.0 6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KKK43956.1 - 5.5e-05 22.2 0.2 0.029 13.2 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.25 KKK43956.1 - 0.0017 17.8 0.1 0.037 13.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 KKK43956.1 - 0.0094 15.6 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Hist_deacetyl PF00850.19 KKK43957.1 - 2.5e-30 106.0 0.0 2.2e-21 76.6 0.0 3.0 1 1 2 3 3 3 3 Histone deacetylase domain Epimerase PF01370.21 KKK43958.1 - 1.3e-29 103.3 0.0 1.6e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK43958.1 - 9.3e-22 77.9 0.0 1.6e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK43958.1 - 5.2e-15 55.2 0.0 6.8e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KKK43958.1 - 9.3e-13 47.9 0.0 1.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KKK43958.1 - 2.4e-07 30.2 0.0 4.2e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KKK43958.1 - 1.2e-06 28.0 0.0 3.1e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KKK43958.1 - 8e-06 25.9 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Aminotran_1_2 PF00155.21 KKK43959.1 - 7.6e-61 206.3 0.0 8.7e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK43959.1 - 0.025 13.9 0.0 4.9 6.4 0.0 2.6 2 1 0 3 3 3 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKK43959.1 - 0.043 13.1 0.1 0.11 11.8 0.1 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KKK43959.1 - 0.044 12.3 0.0 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KKK43959.1 - 0.098 11.4 0.0 0.58 8.8 0.0 2.1 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain PK_C PF02887.16 KKK43960.1 - 6e-10 39.4 0.1 7.9e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain MpPF1 PF07668.11 KKK43962.1 - 0.003 16.9 0.9 0.0032 16.8 0.9 1.2 1 0 0 1 1 1 1 M penetrans paralogue family 1 DUF416 PF04222.12 KKK43962.1 - 0.0049 16.3 0.4 0.0049 16.3 0.4 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF416) DUF4332 PF14229.6 KKK43964.1 - 1.1e-54 183.8 0.0 5.2e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4332) HHH_5 PF14520.6 KKK43964.1 - 1.6e-19 70.3 15.4 3.1e-05 24.5 1.1 5.6 3 2 2 5 5 5 4 Helix-hairpin-helix domain Cdd1 PF11731.8 KKK43964.1 - 5.6e-17 61.7 0.4 4.8e-05 23.5 0.0 4.3 4 0 0 4 4 4 4 Pathogenicity locus DNA_pol_lambd_f PF10391.9 KKK43964.1 - 9.9e-09 34.9 0.0 0.2 11.5 0.0 4.5 4 0 0 4 4 4 2 Fingers domain of DNA polymerase lambda TfoX_C PF04994.13 KKK43964.1 - 2e-07 31.0 0.1 0.35 11.0 0.0 3.5 3 0 0 3 3 3 3 TfoX C-terminal domain BAF PF02961.14 KKK43964.1 - 2.4e-07 31.1 1.4 0.78 10.2 0.1 4.4 4 0 0 4 4 4 2 Barrier to autointegration factor RecG_wedge PF17191.4 KKK43964.1 - 2.5e-06 27.2 2.7 0.5 10.0 0.1 4.0 3 1 0 4 4 4 3 RecG wedge domain Ribosomal_S13 PF00416.22 KKK43964.1 - 3.6e-05 24.2 5.0 1.6 9.1 0.2 4.3 1 1 3 4 4 4 2 Ribosomal protein S13/S18 RNA_pol_A_CTD PF03118.15 KKK43964.1 - 0.0032 17.2 0.2 10 5.9 0.0 4.4 3 1 1 4 4 4 1 Bacterial RNA polymerase, alpha chain C terminal domain IMS_HHH PF11798.8 KKK43964.1 - 0.008 16.4 8.3 12 6.4 0.3 5.2 5 0 0 5 5 5 0 IMS family HHH motif Transposase_22 PF02994.14 KKK43964.1 - 0.055 13.6 5.6 3.4 7.9 0.3 3.0 3 0 0 3 3 3 0 L1 transposable element RBD-like domain Adenylsucc_synt PF00709.21 KKK43964.1 - 0.079 11.9 0.1 1.5 7.6 0.0 2.6 1 1 1 3 3 3 0 Adenylosuccinate synthetase DUF1788 PF08747.11 KKK43964.1 - 0.097 12.7 2.5 16 5.5 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1788) YdaS_antitoxin PF15943.5 KKK43964.1 - 0.12 12.2 1.0 28 4.7 0.0 3.2 4 0 0 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT IFT46_B_C PF12317.8 KKK43964.1 - 0.17 11.6 3.0 0.32 10.7 0.1 2.5 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal AsnC_trans_reg PF01037.21 KKK43965.1 - 1e-14 54.2 0.1 1.1e-14 54.1 0.1 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain Nitroreductase PF00881.24 KKK43966.1 - 4.4e-27 95.2 0.2 6.2e-26 91.5 0.2 2.0 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK43966.1 - 8e-12 45.2 0.4 1.1e-06 28.4 0.0 2.8 2 1 0 2 2 2 2 Putative TM nitroreductase Ras PF00071.22 KKK43967.1 - 2.8e-48 163.6 1.6 2.8e-48 163.6 1.6 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KKK43967.1 - 7.8e-26 90.7 0.3 1.7e-25 89.5 0.2 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK43967.1 - 2.9e-18 65.9 0.4 4.9e-18 65.2 0.4 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK43967.1 - 2.3e-07 30.4 0.9 3.3e-07 29.9 0.9 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK43967.1 - 2.5e-07 30.8 0.1 4.6e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK43967.1 - 0.00018 21.0 0.4 0.0013 18.3 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK43967.1 - 0.00074 19.1 0.1 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK43967.1 - 0.0042 16.5 0.2 0.007 15.8 0.2 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit KAP_NTPase PF07693.14 KKK43967.1 - 0.015 14.6 1.7 1.6 7.9 0.6 2.2 1 1 1 2 2 2 0 KAP family P-loop domain HTH_33 PF13592.6 KKK43969.1 - 1.4e-18 66.3 0.9 3.4e-18 65.0 0.0 2.1 3 0 0 3 3 3 1 Winged helix-turn helix HTH_32 PF13565.6 KKK43969.1 - 1.1e-11 45.2 0.0 2.8e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 KKK43969.1 - 4.9e-10 39.3 0.0 8.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KKK43969.1 - 2.2e-09 36.8 0.1 2.7e-08 33.4 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KKK43969.1 - 7.6e-07 29.2 0.0 2.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain ERK-JNK_inhib PF15002.6 KKK43969.1 - 0.0082 15.8 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 ERK and JNK pathways, inhibitor Terminase_5 PF06056.12 KKK43969.1 - 0.017 15.0 0.0 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Sigma70_r4_2 PF08281.12 KKK43969.1 - 0.02 14.5 0.1 0.091 12.4 0.1 2.1 2 1 0 2 2 2 0 Sigma-70, region 4 Phage_NinH PF06322.11 KKK43969.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage NinH protein DDE_3 PF13358.6 KKK43970.1 - 4.8e-32 110.7 0.0 5.6e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 KKK43970.1 - 0.00077 19.2 0.0 0.00097 18.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_30 PF05430.11 KKK43970.1 - 0.072 13.0 0.2 0.16 11.9 0.2 1.7 1 1 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.16 KKK43971.1 - 3.9e-45 154.3 76.9 1e-34 120.1 37.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK43971.1 - 2.2e-09 36.7 43.1 1.6e-05 24.0 18.4 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 KKK43971.1 - 0.00019 20.0 17.4 0.00023 19.7 17.4 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KKK43971.1 - 0.004 15.5 1.7 0.004 15.5 1.7 2.8 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KKK43971.1 - 0.019 14.3 28.8 0.047 13.0 5.1 2.9 1 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB Lactamase_B_2 PF12706.7 KKK43972.1 - 0.0002 20.9 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK43972.1 - 0.00023 21.2 0.0 0.00029 20.9 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3368 PF11848.8 KKK43978.1 - 0.45 10.3 4.4 2.8 7.8 0.8 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3368) UPF0175 PF03683.13 KKK43979.1 - 1.6e-05 24.5 0.0 3.1e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0175) RHH_1 PF01402.21 KKK43979.1 - 8.8e-05 22.3 1.2 0.00023 21.0 1.2 1.7 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family FAM76 PF16046.5 KKK43982.1 - 0.0082 15.5 3.7 0.011 15.2 3.7 1.2 1 0 0 1 1 1 1 FAM76 protein B12-binding PF02310.19 KKK43983.1 - 6.6e-23 81.0 0.1 1e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 KKK43983.1 - 2.9e-09 37.2 0.4 5.2e-09 36.4 0.1 1.6 2 0 0 2 2 2 1 B12 binding domain Radical_SAM PF04055.21 KKK43983.1 - 0.18 12.2 0.6 0.6 10.5 0.6 1.9 1 1 0 1 1 1 0 Radical SAM superfamily URO-D PF01208.17 KKK43984.1 - 1.9e-27 96.3 0.0 1.3e-23 83.7 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) DUF1254 PF06863.12 KKK43985.1 - 2.7e-06 27.5 0.0 3.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 KKK43985.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) DUF1214 PF06742.11 KKK43986.1 - 5.4e-21 75.1 0.1 7.3e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) LapA_dom PF06305.11 KKK43986.1 - 0.53 10.1 1.7 0.88 9.4 1.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain UPF0175 PF03683.13 KKK43987.1 - 3.4e-08 33.1 0.6 6.5e-08 32.2 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) RHH_1 PF01402.21 KKK43987.1 - 0.00037 20.3 2.3 0.00088 19.1 2.3 1.7 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_3 PF12651.7 KKK43987.1 - 0.00055 19.8 1.7 0.0013 18.7 1.7 1.7 1 0 0 1 1 1 1 Ribbon-helix-helix domain DUF3368 PF11848.8 KKK43988.1 - 2e-07 30.7 0.1 4.6e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3368) HTH_47 PF16221.5 KKK43988.1 - 0.16 11.5 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 winged helix-turn-helix UPF0175 PF03683.13 KKK43989.1 - 1e-07 31.5 0.1 1.6e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0175) RHH_1 PF01402.21 KKK43989.1 - 0.018 15.0 1.5 0.044 13.7 0.3 2.2 2 1 0 2 2 2 0 Ribbon-helix-helix protein, copG family Ints3 PF10189.9 KKK43989.1 - 0.061 12.6 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Integrator complex subunit 3 HI0933_like PF03486.14 KKK43989.1 - 0.11 11.2 0.4 0.12 11.1 0.4 1.0 1 0 0 1 1 1 0 HI0933-like protein ADH_zinc_N_2 PF13602.6 KKK43990.1 - 1.2e-21 78.1 0.0 2.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK43990.1 - 7.6e-12 45.3 0.0 1.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK43990.1 - 4.3e-05 23.3 0.0 0.00012 22.0 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pyr_redox PF00070.27 KKK43990.1 - 0.00065 20.2 0.3 4.4 7.9 0.1 3.6 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KKK43990.1 - 0.0074 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK43990.1 - 0.011 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KKK43990.1 - 0.037 14.3 0.2 0.19 12.0 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_7 PF13241.6 KKK43990.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding PIN_2 PF10130.9 KKK43992.1 - 1.9e-27 96.1 0.2 2.2e-27 95.9 0.2 1.1 1 0 0 1 1 1 1 PIN domain PIN PF01850.21 KKK43992.1 - 0.00066 20.2 0.1 0.00086 19.8 0.1 1.2 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 KKK43992.1 - 0.0011 19.8 0.0 0.0016 19.2 0.0 1.3 1 0 0 1 1 1 1 PIN domain APAF1_C PF17908.1 KKK43992.1 - 0.0018 18.2 0.4 0.0028 17.6 0.4 1.5 1 1 0 1 1 1 1 APAF-1 helical domain POM121 PF15229.6 KKK43997.1 - 0.022 14.4 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 POM121 family SMC_ScpB PF04079.16 KKK43997.1 - 0.025 14.2 0.8 0.073 12.7 0.1 2.0 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB PG_binding_4 PF12229.8 KKK43997.1 - 0.026 14.8 3.4 0.026 14.8 0.4 2.3 2 0 0 2 2 2 0 Putative peptidoglycan binding domain CW_7 PF08230.11 KKK43997.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 CW_7 repeat RNA_pol_Rpb5_N PF03871.14 KKK43997.1 - 0.036 14.6 0.3 0.1 13.2 0.3 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain SpoIIAA-like PF11964.8 KKK43997.1 - 0.11 13.6 0.0 0.2 12.7 0.0 1.5 1 0 0 1 1 1 0 SpoIIAA-like DAGK_cat PF00781.24 KKK43998.1 - 9.5e-28 96.3 0.0 1.5e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 KKK43998.1 - 0.035 14.4 0.1 5.1 7.4 0.0 2.4 1 1 1 2 2 2 0 Diacylglycerol kinase accessory domain Methyltransf_11 PF08241.12 KKK43999.1 - 3.1e-21 75.8 0.0 4.4e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK43999.1 - 1.5e-18 67.3 0.0 2.3e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK43999.1 - 7.4e-18 64.8 0.0 9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK43999.1 - 8.2e-17 61.5 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK43999.1 - 1.3e-10 41.9 0.0 1.9e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KKK43999.1 - 1.9e-06 27.4 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.12 KKK43999.1 - 4.3e-06 26.6 0.0 0.08 12.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 KKK43999.1 - 4.9e-06 26.0 0.0 6.1e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KKK43999.1 - 7.1e-06 25.5 0.0 8.3e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK43999.1 - 0.00043 19.9 0.0 0.00062 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 KKK43999.1 - 0.002 17.8 0.0 0.0093 15.6 0.0 1.9 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 KKK43999.1 - 0.0023 17.5 0.0 0.0037 16.9 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 KKK43999.1 - 0.015 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.13 KKK43999.1 - 0.016 14.7 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 KKK43999.1 - 0.017 15.0 0.0 3.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase N6_N4_Mtase PF01555.18 KKK43999.1 - 0.035 13.8 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 DNA methylase AdoMet_MTase PF07757.13 KKK43999.1 - 0.055 13.8 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_2 PF00891.18 KKK43999.1 - 0.17 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Peptidase_M28 PF04389.17 KKK44000.1 - 5.2e-36 124.2 0.0 6.9e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KKK44000.1 - 0.0028 17.4 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4910 PF16254.5 KKK44000.1 - 0.03 13.2 0.1 4.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4910) LRRC37AB_C PF14914.6 KKK44000.1 - 0.06 13.3 0.3 1 9.3 0.0 2.3 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Glyco_hydro_3_C PF01915.22 KKK44001.1 - 2.1e-56 191.2 0.0 3.9e-55 187.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KKK44001.1 - 2.5e-46 158.5 0.0 3.6e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KKK44001.1 - 1.8e-26 92.0 0.2 3.3e-26 91.2 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Aminotran_3 PF00202.21 KKK44002.1 - 2.7e-122 408.3 0.0 3.1e-122 408.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short_C2 PF13561.6 KKK44003.1 - 1.8e-58 197.9 0.1 2.2e-58 197.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK44003.1 - 1.2e-47 162.0 0.4 1.5e-47 161.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 KKK44003.1 - 0.0031 17.4 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fe-ADH PF00465.19 KKK44004.1 - 8.4e-106 353.8 0.1 9.6e-106 353.7 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK44004.1 - 8.8e-15 55.1 0.6 1.5e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF362 PF04015.12 KKK44005.1 - 0.001 19.3 0.1 0.0018 18.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF362) EF-hand_1 PF00036.32 KKK44005.1 - 0.0014 18.0 1.8 0.0038 16.7 1.8 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KKK44005.1 - 0.0048 17.3 0.1 0.0093 16.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KKK44005.1 - 0.0049 16.3 0.7 0.01 15.3 0.7 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 KKK44005.1 - 0.011 15.6 0.9 0.031 14.1 0.9 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KKK44005.1 - 0.014 15.3 0.4 0.063 13.2 0.5 2.0 2 0 0 2 2 2 0 EF-hand domain Porin_6 PF16939.5 KKK44008.1 - 0.022 13.9 0.2 0.04 13.0 0.2 1.4 1 0 0 1 1 1 0 Putative porin DUF2604 PF10790.9 KKK44008.1 - 0.058 13.7 0.2 0.14 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) CheY-binding PF09078.11 KKK44008.1 - 0.13 12.5 0.3 23 5.2 0.0 2.8 2 0 0 2 2 2 0 CheY binding Rad51 PF08423.11 KKK44009.1 - 2.6e-92 308.7 0.0 3.5e-92 308.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KKK44009.1 - 3.3e-14 53.0 0.1 5e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KKK44009.1 - 4.2e-07 30.5 0.2 1.2e-06 29.0 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 KKK44009.1 - 1.6e-06 27.7 0.2 1.6e-06 27.7 0.2 2.1 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KKK44009.1 - 0.00021 20.9 0.0 0.00052 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain HHH PF00633.23 KKK44009.1 - 0.058 13.3 0.2 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cdd1 PF11731.8 KKK44009.1 - 0.092 13.0 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 Pathogenicity locus CM_1 PF07736.11 KKK44009.1 - 0.11 12.8 0.3 0.23 11.8 0.3 1.5 1 0 0 1 1 1 0 Chorismate mutase type I BSMAP PF12280.8 KKK44009.1 - 0.15 12.3 0.4 0.24 11.6 0.4 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein BAF PF02961.14 KKK44009.1 - 0.16 12.4 0.2 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Barrier to autointegration factor FYDLN_acid PF09538.10 KKK44009.1 - 0.21 12.3 2.9 0.35 11.6 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) AA_kinase PF00696.28 KKK44011.1 - 1.4e-36 126.3 0.0 2e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KKK44011.1 - 3.8e-13 49.0 1.2 1.2e-06 28.2 0.2 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KKK44011.1 - 8.9e-13 47.8 2.3 1.7e-06 27.6 0.0 3.5 3 0 0 3 3 3 2 ACT domain SIS_2 PF13580.6 KKK44011.1 - 0.087 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 SIS domain Interferon PF00143.19 KKK44011.1 - 0.13 12.4 0.1 1.6 8.9 0.0 2.1 2 0 0 2 2 2 0 Interferon alpha/beta domain Fer4_24 PF18109.1 KKK44011.1 - 0.35 11.2 0.1 0.35 11.2 0.1 1.8 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain Lar_N PF09861.9 KKK44012.1 - 1.2e-50 171.5 0.0 2.1e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Lactate racemase N-terminal domain CHIPS PF11434.8 KKK44012.1 - 0.0043 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Chemotaxis-inhibiting protein CHIPS DUF362 PF04015.12 KKK44012.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF362) Glycos_transf_2 PF00535.26 KKK44014.1 - 2e-17 63.5 0.1 2.8e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 KKK44014.1 - 7.2e-07 29.6 0.1 1.4e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KKK44014.1 - 0.0014 18.6 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KKK44014.1 - 0.0067 15.9 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Methyltransf_11 PF08241.12 KKK44015.1 - 6e-18 65.3 0.0 1.1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK44015.1 - 8.1e-14 52.1 0.0 1.4e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK44015.1 - 2.8e-13 50.0 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK44015.1 - 6.8e-10 38.9 0.3 1.6e-09 37.7 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK44015.1 - 5.5e-09 36.7 0.0 1.2e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK44015.1 - 4.5e-06 26.2 0.0 7.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 KKK44015.1 - 1.5e-05 23.8 0.0 2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pox_MCEL PF03291.16 KKK44015.1 - 0.0011 18.1 2.1 0.61 9.1 0.0 2.3 1 1 1 2 2 2 2 mRNA capping enzyme DREV PF05219.12 KKK44015.1 - 0.002 17.2 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 KKK44015.1 - 0.0039 16.8 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 KKK44015.1 - 0.046 13.6 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase CMAS PF02353.20 KKK44015.1 - 0.095 12.0 0.2 0.25 10.6 0.2 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MmcB-like PF06319.12 KKK44015.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA repair protein MmcB-like LPG_synthase_TM PF03706.13 KKK44016.1 - 2.4e-32 112.7 15.9 2.9e-32 112.4 15.9 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region Peptidase_U32 PF01136.19 KKK44017.1 - 2.5e-77 259.2 0.3 3.5e-77 258.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase family U32 Spc29 PF17082.5 KKK44019.1 - 0.0047 16.8 1.0 0.0061 16.4 1.0 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 OrfB_Zn_ribbon PF07282.11 KKK44019.1 - 0.1 12.5 0.1 0.34 10.9 0.1 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Telomerase_RBD PF12009.8 KKK44019.1 - 0.17 12.0 3.4 1.7 8.7 0.1 2.6 3 0 0 3 3 3 0 Telomerase ribonucleoprotein complex - RNA binding domain PVL_ORF50 PF07768.11 KKK44021.1 - 0.035 14.4 0.6 0.042 14.2 0.6 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family rve_3 PF13683.6 KKK44021.1 - 0.051 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DUF4969 PF16339.5 KKK44022.1 - 0.038 14.3 0.7 0.065 13.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) FTCD_N PF07837.12 KKK44023.1 - 1.2e-62 210.8 0.1 2.6e-62 209.7 0.0 1.5 2 0 0 2 2 2 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.14 KKK44023.1 - 9.6e-18 64.6 0.1 2.6e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 Formiminotransferase domain Amidohydro_1 PF01979.20 KKK44024.1 - 1.6e-17 63.9 0.2 6.4e-17 61.9 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KKK44024.1 - 7.3e-13 48.8 0.0 9e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family NosD PF05048.13 KKK44026.1 - 1.9e-61 207.4 153.8 1.3e-25 90.1 32.4 4.0 2 1 2 4 4 4 4 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK44026.1 - 2.1e-45 154.4 113.4 1.4e-20 73.7 37.2 3.6 1 1 2 3 3 3 3 Right handed beta helix region Acyltransferase PF01553.21 KKK44028.1 - 4e-09 36.2 0.0 5.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase YdjM PF04307.14 KKK44029.1 - 2.5e-07 30.1 2.5 4e-07 29.5 2.6 1.4 1 1 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase DUF2207 PF09972.9 KKK44029.1 - 0.0097 14.7 1.3 0.0097 14.7 1.3 2.2 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) Jagunal PF07086.12 KKK44029.1 - 0.047 13.7 7.1 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF4131 PF13567.6 KKK44029.1 - 0.07 12.8 0.2 0.07 12.8 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PEMT PF04191.13 KKK44030.1 - 9e-08 32.5 0.6 9e-08 32.5 0.6 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KKK44030.1 - 1.1e-07 31.6 0.5 2.1e-07 30.7 0.1 1.6 1 1 1 2 2 2 1 NnrU protein ICMT PF04140.14 KKK44030.1 - 1.2e-07 32.1 2.1 1.2e-07 32.1 2.1 2.1 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KKK44030.1 - 1.4e-05 24.0 0.2 1.4e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KKK44030.1 - 0.0083 15.7 0.6 0.014 14.9 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KKK44030.1 - 0.015 15.3 0.8 0.015 15.3 0.8 2.1 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3460 PF11943.8 KKK44030.1 - 0.028 14.7 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) DUF3899 PF13038.6 KKK44030.1 - 0.14 12.6 9.8 0.08 13.5 2.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF3671 PF12420.8 KKK44030.1 - 0.99 9.5 0.0 0.99 9.5 0.0 3.8 1 1 1 2 2 1 0 Protein of unknown function MFS_1 PF07690.16 KKK44030.1 - 1 8.2 20.7 0.0071 15.3 5.6 2.1 1 1 0 2 2 2 0 Major Facilitator Superfamily MerC PF03203.14 KKK44030.1 - 1.1 9.7 7.1 0.23 11.9 0.9 2.5 1 1 2 3 3 3 0 MerC mercury resistance protein Mon1 PF03164.14 KKK44031.1 - 1.1e-08 34.6 0.7 1.3e-08 34.3 0.7 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF4377 PF14302.6 KKK44031.1 - 0.11 12.5 0.2 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) Ras PF00071.22 KKK44032.1 - 8.9e-47 158.7 1.3 1e-46 158.5 1.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44032.1 - 3.7e-30 104.6 0.3 5.8e-30 104.0 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44032.1 - 8e-16 58.0 1.8 1e-15 57.7 1.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK44032.1 - 3e-08 33.3 2.5 3.5e-08 33.1 2.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK44032.1 - 3.8e-08 33.4 0.6 5.6e-08 32.9 0.2 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK44032.1 - 0.00011 21.8 2.7 0.0012 18.4 2.7 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KKK44032.1 - 0.00013 21.9 0.5 0.0054 16.6 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 KKK44032.1 - 0.00088 18.6 1.2 0.076 12.3 0.0 2.2 2 0 0 2 2 2 2 Septin RsgA_GTPase PF03193.16 KKK44032.1 - 0.0015 18.5 0.6 1.6 8.6 0.2 2.2 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KKK44032.1 - 0.0037 16.5 4.9 0.07 12.3 3.1 2.7 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 KKK44032.1 - 0.011 16.1 0.1 0.04 14.2 0.0 2.0 3 0 0 3 3 3 0 AAA domain PTS_IIB PF02302.17 KKK44032.1 - 0.012 16.3 0.1 0.78 10.5 0.0 2.4 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit NTPase_1 PF03266.15 KKK44032.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.5 1 1 0 1 1 1 0 NTPase GTP_EFTU PF00009.27 KKK44032.1 - 0.014 15.0 0.5 0.091 12.3 0.3 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.29 KKK44032.1 - 0.015 15.7 0.1 0.073 13.5 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KKK44032.1 - 0.017 14.8 2.1 0.052 13.3 2.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KKK44032.1 - 0.087 12.8 0.0 1.5 8.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) HTH_47 PF16221.5 KKK44033.1 - 0.00029 20.3 0.1 1.3 8.6 0.0 2.9 3 0 0 3 3 3 2 winged helix-turn-helix PqqD PF05402.12 KKK44033.1 - 0.25 11.7 1.1 0.78 10.1 0.0 2.4 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Acetyltransf_1 PF00583.25 KKK44034.1 - 0.00016 21.9 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK44034.1 - 0.0024 18.2 0.1 0.0079 16.6 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK44034.1 - 0.032 14.2 0.0 5.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 KKK44035.1 - 1.4e-07 31.8 0.1 2.9e-06 27.5 0.0 2.9 3 1 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKK44035.1 - 6.5e-05 23.2 0.0 0.024 14.9 0.0 3.0 1 1 2 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2207 PF09972.9 KKK44036.1 - 0.0014 17.5 4.5 0.0021 16.9 4.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SeqA PF03925.13 KKK44036.1 - 0.076 13.0 0.4 2.8 7.9 0.1 2.5 2 0 0 2 2 2 0 SeqA protein C-terminal domain DUF2721 PF11026.8 KKK44036.1 - 2.6 7.9 8.3 9.1 6.2 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) PUD PF03714.14 KKK44037.1 - 0.26 12.2 1.5 0.47 11.4 1.5 1.6 1 1 0 1 1 1 0 Bacterial pullanase-associated domain ParB_C PF18064.1 KKK44038.1 - 0.03 14.5 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal RHH_1 PF01402.21 KKK44038.1 - 0.073 13.0 0.9 0.55 10.2 0.9 2.0 1 1 0 1 1 1 0 Ribbon-helix-helix protein, copG family PAS_3 PF08447.12 KKK44039.1 - 3.1e-79 261.3 3.1 1.4e-18 67.0 0.0 9.0 9 0 0 9 9 9 7 PAS fold PAS_9 PF13426.7 KKK44039.1 - 7.7e-70 231.8 23.1 1.6e-11 44.4 0.1 10.0 10 0 0 10 10 10 9 PAS domain PAS PF00989.25 KKK44039.1 - 3e-67 223.7 0.2 3.7e-13 49.5 0.0 9.5 9 0 0 9 9 9 9 PAS fold PAS_4 PF08448.10 KKK44039.1 - 7.1e-57 190.4 0.0 1.8e-09 37.8 0.0 9.8 10 0 0 10 10 10 5 PAS fold PAS_8 PF13188.7 KKK44039.1 - 8.8e-37 124.5 0.0 4e-05 23.5 0.0 9.4 10 0 0 10 10 10 7 PAS domain PAS_7 PF12860.7 KKK44039.1 - 6.5e-14 52.1 12.8 5.5e-09 36.2 0.0 9.1 11 1 0 11 11 11 1 PAS fold PAS_11 PF14598.6 KKK44039.1 - 1.1e-07 32.0 0.1 0.0014 18.8 0.0 5.7 6 0 0 6 6 6 1 PAS domain ZNRF_3_ecto PF18212.1 KKK44039.1 - 0.00039 20.4 5.2 22 5.1 0.0 7.3 8 0 0 8 8 8 0 ZNRF-3 Ectodomain PAS_12 PF18095.1 KKK44039.1 - 0.0026 17.4 4.3 3.3 7.3 0.0 5.1 5 0 0 5 5 5 1 UPF0242 C-terminal PAS-like domain ATP-synt_F PF01990.17 KKK44039.1 - 0.037 14.4 10.4 11 6.4 0.1 4.9 5 0 0 5 5 5 0 ATP synthase (F/14-kDa) subunit HisKA PF00512.25 KKK44039.1 - 0.13 12.3 0.0 0.5 10.4 0.0 2.1 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF4786 PF16027.5 KKK44039.1 - 0.15 12.6 0.1 0.35 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) SCP2_2 PF13530.6 KKK44041.1 - 6.5e-15 55.4 0.0 8.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain DUF366 PF04017.12 KKK44043.1 - 0.039 13.4 0.1 0.079 12.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF366) D123 PF07065.14 KKK44043.1 - 0.039 13.1 0.4 0.051 12.7 0.4 1.3 1 1 0 1 1 1 0 D123 Acyl_transf_3 PF01757.22 KKK44045.1 - 0.33 10.0 26.5 0.042 12.9 5.2 2.1 1 1 1 2 2 2 0 Acyltransferase family Hydrolase_4 PF12146.8 KKK44047.1 - 2.4e-20 72.8 0.0 1.1e-13 51.0 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK44047.1 - 3.1e-12 46.7 0.3 2.5e-06 27.4 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KKK44047.1 - 6.8e-07 29.3 0.0 0.0035 17.2 0.0 3.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KKK44047.1 - 2.7e-05 23.7 0.0 6e-05 22.6 0.0 1.6 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KKK44047.1 - 0.00012 21.9 0.0 0.21 11.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 KKK44047.1 - 0.00014 21.6 0.0 0.11 12.1 0.0 2.0 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 KKK44047.1 - 0.005 16.5 0.0 0.011 15.4 0.0 1.7 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KKK44047.1 - 0.0057 17.3 0.0 0.85 10.2 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KKK44047.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family ERp29_N PF07912.13 KKK44047.1 - 0.044 13.9 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 ERp29, N-terminal domain Abhydrolase_4 PF08386.10 KKK44047.1 - 0.058 13.5 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Rhodanese PF00581.20 KKK44049.1 - 5.1e-14 52.7 0.0 7.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Ac76 PF05814.11 KKK44049.1 - 3.1 7.9 8.0 0.44 10.6 1.4 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) His_Phos_1 PF00300.22 KKK44050.1 - 3.5e-32 111.7 0.0 3.8e-25 88.7 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Glyco_hydro_2_N PF02837.18 KKK44051.1 - 9e-20 71.3 2.5 3.8e-19 69.2 2.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KKK44051.1 - 1.2e-16 60.7 0.0 5.8e-15 55.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KKK44051.1 - 4.2e-07 30.6 0.0 8.3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KKK44051.1 - 0.016 15.8 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Nitroreductase PF00881.24 KKK44053.1 - 4.3e-29 101.7 0.0 5e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK44053.1 - 1e-06 28.5 0.1 0.0092 15.6 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase Acetyltransf_3 PF13302.7 KKK44054.1 - 6.8e-22 78.6 0.0 8.4e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK44054.1 - 0.00028 21.1 0.0 0.00038 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KKK44054.1 - 0.0066 16.6 0.3 0.0089 16.2 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Esterase PF00756.20 KKK44056.1 - 4.4e-22 78.9 0.0 5.4e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KKK44056.1 - 0.0013 18.1 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KKK44056.1 - 0.0035 16.9 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KKK44056.1 - 0.025 14.2 0.0 0.052 13.2 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KKK44056.1 - 0.031 14.1 0.1 0.48 10.2 0.1 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KKK44056.1 - 0.07 12.0 0.0 0.43 9.5 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme Alkyl_sulf_dimr PF14863.6 KKK44058.1 - 7.9e-28 97.6 0.0 1.4e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KKK44058.1 - 4.7e-17 62.6 0.1 7e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK44058.1 - 0.0007 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PALP PF00291.25 KKK44058.1 - 0.052 13.0 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme BacA PF02673.18 KKK44059.1 - 0.04 13.6 4.0 0.054 13.2 0.1 2.3 2 1 0 2 2 2 0 Bacitracin resistance protein BacA DUF3671 PF12420.8 KKK44059.1 - 0.047 13.8 4.5 0.26 11.4 4.5 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF4064 PF13273.6 KKK44059.1 - 0.63 10.4 0.1 0.63 10.4 0.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 KKK44059.1 - 0.81 8.4 21.3 0.024 13.4 4.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 KKK44059.1 - 6 7.0 12.3 0.22 11.6 2.3 2.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase FeoB_associated PF12669.7 KKK44059.1 - 8.7 6.8 11.7 2.5 8.6 0.3 4.0 4 0 0 4 4 4 0 FeoB-associated Cys-rich membrane protein 3HCDH_N PF02737.18 KKK44060.1 - 1.1e-54 185.1 2.0 1.5e-54 184.6 2.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK44060.1 - 5.3e-23 81.5 0.0 3.2e-18 66.1 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KKK44060.1 - 1.8e-08 34.7 0.5 7.5e-08 32.7 0.8 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KKK44060.1 - 0.0016 18.5 0.2 0.0023 17.9 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 KKK44060.1 - 0.0064 16.1 1.1 0.01 15.4 1.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KKK44060.1 - 0.02 15.3 0.2 0.033 14.6 0.2 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KKK44060.1 - 0.057 12.7 3.7 0.087 12.1 3.4 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KKK44060.1 - 0.078 13.5 0.4 0.19 12.3 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KKK44060.1 - 0.09 13.4 1.9 0.67 10.6 1.8 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 KKK44060.1 - 0.093 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HTH_Tnp_Tc3_1 PF11427.8 KKK44060.1 - 0.12 12.2 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Tc3 transposase Alkyl_sulf_dimr PF14863.6 KKK44061.1 - 6.7e-28 97.9 0.0 1.1e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KKK44061.1 - 7.2e-18 65.3 0.0 1.2e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK44061.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain YfdX PF10938.8 KKK44061.1 - 0.012 15.5 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 YfdX protein TPR_19 PF14559.6 KKK44061.1 - 0.056 14.0 0.4 0.056 14.0 0.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CPSase_sm_chain PF00988.22 KKK44063.1 - 2.2e-45 153.6 0.0 3.3e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KKK44063.1 - 9.6e-38 129.9 0.0 1.4e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKK44063.1 - 0.0033 17.2 0.2 0.01 15.6 0.1 1.8 1 1 1 2 2 2 1 Peptidase C26 AlkA_N PF06029.11 KKK44063.1 - 0.022 15.0 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 AlkA N-terminal domain DUF2193 PF09959.9 KKK44063.1 - 0.14 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) CPSase_L_D2 PF02786.17 KKK44064.1 - 1.6e-102 341.5 0.0 7.9e-74 247.7 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KKK44064.1 - 3.1e-36 124.4 0.1 9.7e-36 122.8 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KKK44064.1 - 1.8e-13 50.4 0.0 1.8e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KKK44064.1 - 1.5e-11 44.2 0.0 5.3e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 KKK44064.1 - 5.4e-07 29.7 0.1 1.4e-05 25.2 0.0 3.4 3 0 0 3 3 3 1 MGS-like domain GARS_A PF01071.19 KKK44064.1 - 1.3e-05 25.1 0.1 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KKK44064.1 - 0.0017 18.5 1.2 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 KKK44064.1 - 0.078 12.4 0.0 12 5.3 0.0 2.8 2 0 0 2 2 2 0 ATP-grasp domain G_glu_transpept PF01019.21 KKK44067.1 - 2e-115 386.5 0.0 2.3e-115 386.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ras PF00071.22 KKK44068.1 - 1.9e-30 105.6 0.0 2.3e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44068.1 - 1.6e-24 86.4 0.0 2.6e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44068.1 - 4.8e-12 45.7 0.0 8.4e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK44068.1 - 0.00038 20.5 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 KKK44068.1 - 0.0021 18.1 0.0 0.0065 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KKK44068.1 - 0.0027 17.1 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKK44068.1 - 0.0057 16.6 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 KKK44068.1 - 0.0072 15.6 0.3 0.071 12.4 0.0 2.0 2 0 0 2 2 2 1 Septin AAA_23 PF13476.6 KKK44068.1 - 0.015 15.8 0.4 0.022 15.3 0.4 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK44068.1 - 0.029 13.9 0.1 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 KKK44068.1 - 0.14 12.4 0.0 0.56 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK44068.1 - 0.18 12.0 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain polyprenyl_synt PF00348.17 KKK44069.1 - 1.4e-27 96.3 6.2 3.2e-27 95.2 6.2 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase Metallophos_2 PF12850.7 KKK44070.1 - 3.7e-28 98.8 0.0 4.2e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KKK44070.1 - 2.8e-10 41.0 2.3 1.9e-07 31.8 2.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KKK44070.1 - 0.00023 20.6 0.1 0.34 10.2 0.1 2.3 1 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily DUF3524 PF12038.8 KKK44070.1 - 0.074 12.9 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) HEAT_2 PF13646.6 KKK44071.1 - 0.017 15.5 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 HEAT repeats NMO PF03060.15 KKK44075.1 - 9.6e-27 94.2 0.8 1.1e-26 94.0 0.8 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KKK44075.1 - 0.00048 19.3 0.3 0.0007 18.7 0.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK44075.1 - 0.016 14.3 1.4 0.022 13.8 0.7 1.5 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KKK44075.1 - 0.02 14.1 0.2 0.036 13.3 0.2 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase GTP_EFTU_D4 PF14578.6 KKK44075.1 - 0.034 14.1 0.7 0.072 13.0 0.2 1.8 2 1 0 2 2 2 0 Elongation factor Tu domain 4 Response_reg PF00072.24 KKK44075.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain DeoC PF01791.9 KKK44076.1 - 9e-51 172.7 0.0 1.1e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Pox_I1 PF03289.13 KKK44077.1 - 0.012 14.7 0.6 0.015 14.4 0.6 1.2 1 0 0 1 1 1 0 Poxvirus protein I1 TerB_C PF15615.6 KKK44077.1 - 0.033 14.5 0.3 0.04 14.2 0.3 1.1 1 0 0 1 1 1 0 TerB-C domain Phage_int_SAM_4 PF13495.6 KKK44078.1 - 1.3e-12 48.0 1.9 1.3e-12 48.0 1.9 1.6 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 KKK44078.1 - 7.4e-06 26.2 0.3 1.7e-05 25.0 0.1 1.6 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain HEPN_RiboL-PSP PF18735.1 KKK44078.1 - 0.012 15.5 2.6 0.015 15.2 2.6 1.2 1 0 0 1 1 1 0 RiboL-PSP-HEPN Antigen_Bd37 PF11641.8 KKK44078.1 - 0.02 14.4 0.1 0.071 12.6 0.0 1.9 1 1 1 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein LisH_TPL PF17814.1 KKK44078.1 - 0.063 12.9 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 LisH-like dimerisation domain CBM64 PF18666.1 KKK44078.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 Carbohydrate-binding module 64 PfkB PF00294.24 KKK44080.1 - 3.6e-21 75.8 0.0 2.7e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HGTP_anticodon2 PF12745.7 KKK44081.1 - 0.0016 18.0 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs FBA_2 PF07735.17 KKK44081.1 - 0.038 14.1 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 F-box associated Tmemb_9 PF05434.11 KKK44081.1 - 0.038 13.9 1.3 0.054 13.4 1.3 1.2 1 0 0 1 1 1 0 TMEM9 Haem_bd PF14376.6 KKK44082.1 - 0.0047 16.9 0.1 0.0055 16.6 0.1 1.1 1 0 0 1 1 1 1 Haem-binding domain GPI-anchored PF10342.9 KKK44083.1 - 1.4e-13 51.4 20.1 5.4e-07 30.3 3.7 2.8 3 0 0 3 3 3 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-ribbon_3 PF13248.6 KKK44083.1 - 0.00011 21.5 1.0 0.00021 20.6 1.0 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK44083.1 - 0.00011 21.8 1.2 0.00023 20.8 1.2 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK44083.1 - 0.0047 16.9 0.2 0.0087 16.1 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KKK44083.1 - 0.16 11.9 1.0 16 5.5 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal DUF35_N PF12172.8 KKK44083.1 - 0.2 11.5 0.3 0.4 10.6 0.3 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_15 PF17032.5 KKK44083.1 - 0.28 12.0 1.6 0.29 11.9 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbon family Big_7 PF17957.1 KKK44083.1 - 3.6 8.4 8.1 0.73 10.6 0.9 2.6 2 0 0 2 2 2 0 Bacterial Ig domain zf-dskA_traR PF01258.17 KKK44083.1 - 5.3 7.1 6.4 21 5.2 0.3 2.8 2 1 1 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Inhibitor_I36 PF03995.13 KKK44083.1 - 9.4 6.2 7.8 3.8 7.5 1.1 2.7 2 0 0 2 2 2 0 Peptidase inhibitor family I36 UPF0449 PF15136.6 KKK44085.1 - 0.042 14.3 1.7 0.067 13.7 1.5 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 tRNA-synt_2b PF00587.25 KKK44085.1 - 0.065 13.2 0.4 0.09 12.7 0.4 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) PI3K_P85_iSH2 PF16454.5 KKK44085.1 - 1.2 8.7 13.5 16 5.1 10.7 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1002 PF06207.11 KKK44085.1 - 1.4 8.4 10.0 14 5.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) DUF1664 PF07889.12 KKK44085.1 - 1.6 8.8 5.1 2.5 8.1 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Uteroglobin PF01099.17 KKK44086.1 - 0.03 14.7 0.1 0.08 13.3 0.1 1.7 1 0 0 1 1 1 0 Uteroglobin family MSA-2c PF12238.8 KKK44086.1 - 0.062 13.3 1.5 0.14 12.1 1.5 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Zot PF05707.12 KKK44088.1 - 0.0012 18.6 0.1 0.013 15.2 0.0 2.2 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 KKK44088.1 - 0.0077 16.6 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KKK44088.1 - 0.021 14.9 0.0 0.021 14.9 0.0 2.8 3 1 0 3 3 3 0 AAA domain Pam16 PF03656.13 KKK44088.1 - 0.26 11.3 1.8 1.2 9.1 0.1 2.6 3 0 0 3 3 3 0 Pam16 DUF2970 PF11174.8 KKK44089.1 - 0.21 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Aida_N PF08910.10 KKK44090.1 - 0.091 13.2 0.8 0.27 11.6 0.8 1.8 1 0 0 1 1 1 0 Aida N-terminus DUF2516 PF10724.9 KKK44091.1 - 0.13 12.5 2.4 0.57 10.5 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2516) Syndecan PF01034.20 KKK44091.1 - 0.25 11.3 4.9 1.1 9.2 0.6 2.1 2 0 0 2 2 2 0 Syndecan domain UPF0114 PF03350.16 KKK44092.1 - 0.056 13.7 4.0 0.076 13.2 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 DUF2207 PF09972.9 KKK44092.1 - 0.49 9.1 1.5 0.61 8.8 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GNVR PF13807.6 KKK44092.1 - 1.1 9.2 4.4 3 7.8 0.1 2.3 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Herpes_US9 PF06072.11 KKK44092.1 - 1.7 8.6 9.6 3.6 7.5 1.2 2.4 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 MscS_TM PF12794.7 KKK44093.1 - 0.0059 15.5 0.0 0.0065 15.4 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 YIF1 PF03878.15 KKK44094.1 - 0.054 13.0 11.4 0.014 14.9 8.0 1.6 1 1 0 1 1 1 0 YIF1 DUF2070 PF09843.9 KKK44097.1 - 4.1 5.6 22.0 5.5 5.2 22.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3899 PF13038.6 KKK44098.1 - 0.012 16.1 0.1 0.014 15.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) CPBP PF02517.16 KKK44099.1 - 4.7e-12 46.1 8.3 4.7e-12 46.1 8.3 2.3 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease BC10 PF06726.12 KKK44099.1 - 0.029 14.6 4.3 0.073 13.3 0.8 2.7 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 DUF485 PF04341.12 KKK44100.1 - 0.048 13.6 0.1 0.096 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 OAD_gamma PF04277.13 KKK44100.1 - 0.12 13.0 0.1 0.2 12.3 0.1 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-C2HE PF16278.5 KKK44103.1 - 0.089 13.3 2.0 0.55 10.7 0.2 2.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 KKK44103.1 - 0.35 10.9 3.8 12 6.0 0.4 2.2 2 0 0 2 2 2 0 BED zinc finger Fer4 PF00037.27 KKK44104.1 - 6.1e-05 22.7 1.8 6.1e-05 22.7 1.8 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_7 PF12838.7 KKK44104.1 - 0.00012 22.5 7.4 0.00024 21.6 7.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK44104.1 - 0.001 19.6 2.9 0.13 12.8 0.1 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44104.1 - 0.0088 16.1 2.0 0.0088 16.1 2.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KKK44104.1 - 0.022 14.9 10.1 0.026 14.7 2.1 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44104.1 - 0.024 15.5 12.5 0.44 11.5 12.5 2.4 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK44104.1 - 0.076 13.1 11.0 0.74 10.0 11.3 2.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK44104.1 - 0.11 13.1 1.3 0.11 13.1 1.3 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_21 PF14697.6 KKK44104.1 - 0.56 10.4 10.1 0.51 10.5 8.4 1.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK44104.1 - 1.4 9.4 7.8 83 3.7 7.8 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain FrhB_FdhB_C PF04432.13 KKK44107.1 - 6.6e-36 123.5 0.0 6.6e-36 123.5 0.0 2.1 3 0 0 3 3 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK44107.1 - 9.7e-25 86.5 0.0 2e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term TrmB PF01978.19 KKK44107.1 - 3.6e-07 30.0 0.0 9.1e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fer4_10 PF13237.6 KKK44107.1 - 0.00025 21.1 7.4 0.0095 16.0 0.7 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK44107.1 - 0.011 15.9 10.9 0.062 13.5 8.1 2.8 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK44107.1 - 0.015 15.8 3.8 0.13 12.9 0.2 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44107.1 - 0.018 14.9 1.0 0.018 14.9 1.0 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK44107.1 - 0.041 14.0 2.6 0.041 14.0 2.6 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK44107.1 - 0.075 13.6 6.6 0.25 11.9 0.8 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK44107.1 - 0.1 13.1 4.5 2.6 8.7 0.9 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 KKK44107.1 - 0.11 13.0 4.3 0.39 11.2 0.2 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44107.1 - 0.29 12.1 9.3 0.92 10.5 0.1 3.5 4 0 0 4 4 4 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK44107.1 - 1.8 8.8 8.3 12 6.1 8.4 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK44107.1 - 2.8 9.1 11.9 14 6.9 4.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KKK44107.1 - 3.5 7.8 7.6 1.1 9.4 1.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Succ_CoA_lig PF13607.6 KKK44108.1 - 3.9e-39 133.6 0.0 1.8e-38 131.4 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK44108.1 - 9.6e-17 61.5 0.0 2.1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 KKK44108.1 - 9.5e-10 39.0 0.1 2.7e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain G_glu_transpept PF01019.21 KKK44113.1 - 2.1e-114 383.2 0.0 2.3e-114 383.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ras PF00071.22 KKK44114.1 - 4.2e-32 111.0 0.1 4.9e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44114.1 - 2.2e-26 92.4 0.0 3.8e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44114.1 - 1.7e-13 50.4 0.0 2.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK44114.1 - 5.4e-05 23.3 0.0 9.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KKK44114.1 - 0.00013 21.6 0.0 0.00072 19.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK44114.1 - 0.00033 20.1 0.0 0.00054 19.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KKK44114.1 - 0.00064 19.8 0.0 0.0017 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KKK44114.1 - 0.00064 19.6 0.4 0.0017 18.2 0.1 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 KKK44114.1 - 0.0028 17.0 0.3 0.079 12.2 0.0 2.0 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 KKK44114.1 - 0.0039 17.1 0.1 0.41 10.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KKK44114.1 - 0.0054 17.2 0.8 0.0068 16.9 0.8 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KKK44114.1 - 0.0057 16.2 0.1 0.8 9.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 KKK44114.1 - 0.011 16.0 0.0 0.085 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK44114.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain polyprenyl_synt PF00348.17 KKK44115.1 - 2.5e-28 98.8 4.8 4.9e-28 97.9 4.8 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase Metallophos_2 PF12850.7 KKK44116.1 - 4e-28 98.7 0.0 4.6e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KKK44116.1 - 7.2e-12 46.2 1.4 2.8e-08 34.5 0.5 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KKK44116.1 - 0.00012 21.5 0.1 0.036 13.4 0.1 2.3 1 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily HTH_IclR PF09339.10 KKK44117.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain FTR_C PF02741.15 KKK44119.1 - 6.2e-62 208.0 0.4 8.8e-62 207.5 0.4 1.2 1 0 0 1 1 1 1 FTR, proximal lobe FTR PF01913.18 KKK44119.1 - 2.5e-51 173.3 0.0 3.8e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Formylmethanofuran-tetrahydromethanopterin formyltransferase DUF4625 PF15418.6 KKK44120.1 - 0.0006 20.1 0.3 0.63 10.3 0.1 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4625) MG2 PF01835.19 KKK44120.1 - 0.015 15.7 0.0 0.15 12.5 0.0 2.5 3 0 0 3 3 3 0 MG2 domain DUF4064 PF13273.6 KKK44120.1 - 0.092 13.0 1.8 6.6 7.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) ECF-ribofla_trS PF07155.12 KKK44120.1 - 0.5 10.3 4.3 6.6 6.7 0.4 2.6 2 1 0 2 2 2 0 ECF-type riboflavin transporter, S component HGTP_anticodon PF03129.20 KKK44122.1 - 1.2e-21 76.7 0.2 2.4e-21 75.7 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKK44122.1 - 4.5e-12 46.3 0.1 2.1e-11 44.1 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KKK44122.1 - 0.036 13.2 1.3 4.8 6.2 1.4 3.2 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) TRAF6_Z2 PF18048.1 KKK44122.1 - 0.069 13.3 0.2 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 CxC5 PF18718.1 KKK44122.1 - 0.19 11.8 1.3 19 5.4 0.1 2.3 1 1 1 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases zinc_ribbon_4 PF13717.6 KKK44122.1 - 0.27 11.2 3.4 12 5.9 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 KKK44122.1 - 1 9.2 2.9 8.7 6.2 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF202 PF02656.15 KKK44123.1 - 0.066 13.7 0.1 0.066 13.7 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF202) UPF0182 PF03699.13 KKK44123.1 - 0.26 9.4 8.5 0.35 9.0 8.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) LMP PF04778.12 KKK44124.1 - 0.0012 18.8 6.7 0.0012 18.8 6.7 2.3 2 0 0 2 2 2 1 LMP repeated region DUF2914 PF11141.8 KKK44124.1 - 0.09 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) CK_II_beta PF01214.18 KKK44124.1 - 0.56 10.0 6.1 4.1 7.2 0.7 2.4 1 1 0 2 2 2 0 Casein kinase II regulatory subunit Acetyltransf_1 PF00583.25 KKK44125.1 - 1.6e-05 25.1 0.0 2.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK44125.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK44125.1 - 0.015 15.7 0.1 0.03 14.8 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK44125.1 - 0.02 14.9 0.0 0.052 13.5 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein TPR_12 PF13424.6 KKK44126.1 - 7.3e-27 93.5 21.5 3.6e-05 24.0 0.1 6.0 4 1 3 7 7 7 7 Tetratricopeptide repeat SNAP PF14938.6 KKK44126.1 - 8.7e-13 48.3 17.2 9.7e-07 28.5 1.3 4.3 1 1 4 5 5 5 4 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KKK44126.1 - 7.9e-12 44.3 34.6 0.00015 21.6 0.9 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KKK44126.1 - 3.2e-10 39.4 41.2 0.0054 16.9 1.4 7.9 6 1 2 8 8 8 4 Tetratricopeptide repeat RPN7 PF10602.9 KKK44126.1 - 9.4e-08 32.0 14.6 0.021 14.5 1.0 4.0 2 2 2 4 4 4 3 26S proteasome subunit RPN7 TPR_1 PF00515.28 KKK44126.1 - 1.1e-07 31.4 36.4 6.7e-05 22.5 2.2 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.6 KKK44126.1 - 5.2e-05 23.0 18.1 0.017 15.0 0.2 6.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK44126.1 - 0.00054 19.4 0.2 0.1 11.9 0.0 3.4 2 1 1 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 KKK44126.1 - 0.0006 20.3 19.7 0.49 11.2 0.2 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 KKK44126.1 - 0.0013 18.1 2.1 0.0023 17.3 2.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK44126.1 - 0.0022 17.7 4.3 0.0022 17.7 4.3 1.8 2 0 0 2 2 2 1 zinc-ribbon domain TPR_7 PF13176.6 KKK44126.1 - 0.0027 17.6 18.6 0.53 10.4 0.2 6.7 6 1 0 6 6 6 1 Tetratricopeptide repeat DZR PF12773.7 KKK44126.1 - 0.0031 17.5 0.6 0.0055 16.7 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon SHNi-TPR PF10516.9 KKK44126.1 - 0.035 13.6 5.9 0.79 9.2 0.1 4.4 4 0 0 4 4 4 0 SHNi-TPR TPR_16 PF13432.6 KKK44126.1 - 0.05 14.3 6.7 77 4.1 0.0 5.6 5 2 1 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 KKK44126.1 - 0.15 12.7 11.7 8.3 7.2 1.5 4.9 4 1 0 4 4 4 0 Sel1 repeat zinc-ribbons_6 PF07191.12 KKK44126.1 - 0.2 11.7 0.6 14 5.8 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2225 PF09986.9 KKK44126.1 - 0.55 9.9 34.3 0.33 10.6 11.9 4.8 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_10 PF16588.5 KKK44126.1 - 2 8.2 5.8 5 6.9 1.1 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger NOB1_Zn_bind PF08772.11 KKK44127.1 - 0.00082 19.5 0.9 0.00092 19.3 0.9 1.1 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-dskA_traR PF01258.17 KKK44127.1 - 0.00097 19.0 2.2 0.54 10.2 0.4 2.1 2 0 0 2 2 2 2 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 KKK44127.1 - 0.0015 18.6 0.7 0.0017 18.3 0.7 1.1 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK44127.1 - 0.0079 16.9 2.4 0.0094 16.7 2.4 1.2 1 0 0 1 1 1 1 zinc-ribbon family HypA PF01155.19 KKK44127.1 - 0.012 15.6 0.5 0.013 15.5 0.5 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 KKK44127.1 - 0.075 12.6 3.4 3.6 7.2 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PolC_DP2 PF03833.13 KKK44127.1 - 0.11 10.3 0.4 0.11 10.4 0.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Rubredoxin_2 PF18073.1 KKK44127.1 - 0.12 12.1 4.0 0.26 11.1 4.0 1.5 1 1 0 1 1 1 0 Rubredoxin metal binding domain Zn-ribbon_8 PF09723.10 KKK44127.1 - 0.13 12.3 6.4 0.66 10.1 6.4 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KKK44127.1 - 0.25 10.8 4.8 3.3 7.3 4.8 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK44127.1 - 0.39 10.5 6.4 4.5 7.1 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_13 PF18508.1 KKK44127.1 - 2 8.1 6.9 0.75 9.4 0.6 2.3 1 1 1 2 2 2 0 Zinc finger domain ECH_1 PF00378.20 KKK44128.1 - 1e-52 179.0 0.0 1.2e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK44128.1 - 8.4e-26 91.2 0.0 9.8e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TPR_12 PF13424.6 KKK44129.1 - 5.9e-23 81.0 0.0 4.1e-08 33.4 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKK44129.1 - 3.2e-13 48.9 13.6 0.028 14.2 0.1 7.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK44129.1 - 6.7e-12 44.6 1.6 0.019 15.0 0.0 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK44129.1 - 2e-11 43.1 3.6 0.04 14.0 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK44129.1 - 5.1e-11 41.9 10.3 0.14 12.4 0.0 7.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK44129.1 - 1.9e-07 30.8 0.0 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 2 MalT-like TPR region TPR_11 PF13414.6 KKK44129.1 - 2.7e-05 23.7 0.3 0.092 12.4 0.1 4.7 5 0 0 5 5 5 1 TPR repeat SNAP PF14938.6 KKK44129.1 - 4.6e-05 23.0 0.1 0.15 11.4 0.0 2.1 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KKK44129.1 - 8.3e-05 22.3 0.0 3.9 7.5 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 KKK44129.1 - 0.00054 20.2 0.0 0.0019 18.5 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK44129.1 - 0.0024 18.4 0.0 7 7.5 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 KKK44129.1 - 0.0025 17.9 1.2 34 5.0 0.0 4.4 4 0 0 4 4 4 0 PPR repeat DUF3856 PF12968.7 KKK44129.1 - 0.0097 16.0 0.3 0.44 10.6 0.1 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) FliS_cochap PF16522.5 KKK44129.1 - 0.0099 15.8 3.0 0.031 14.2 0.2 2.5 2 0 0 2 2 2 1 Flagellar FLiS export co-chaperone, HP1076 ANAPC5 PF12862.7 KKK44129.1 - 0.016 15.2 0.2 0.67 10.1 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_16 PF13432.6 KKK44129.1 - 0.022 15.4 0.0 12 6.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK44129.1 - 0.032 15.0 0.0 66 4.7 0.0 4.9 5 2 0 5 5 5 0 Tetratricopeptide repeat DUF1825 PF08855.10 KKK44129.1 - 0.058 13.3 2.6 1.1 9.2 0.4 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF1825) C_GCAxxG_C_C PF09719.10 KKK44130.1 - 1.4e-20 73.8 0.2 1.5e-20 73.6 0.2 1.0 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) Radical_SAM PF04055.21 KKK44131.1 - 1.4e-19 71.1 0.0 2.8e-19 70.1 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK44131.1 - 1.2e-05 25.6 0.0 3.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain zf-ribbon_3 PF13248.6 KKK44131.1 - 0.44 10.0 8.3 0.61 9.6 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain CcmH PF03918.14 KKK44131.1 - 2.4 7.4 3.8 1.8 7.8 0.0 2.3 3 0 0 3 3 3 0 Cytochrome C biogenesis protein zf-C4_Topoisom PF01396.19 KKK44131.1 - 8.4 6.3 9.0 8.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger TMEM252 PF15664.5 KKK44132.1 - 0.75 9.5 4.2 3.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 252 family DAO PF01266.24 KKK44133.1 - 1.8e-54 185.6 0.0 2.5e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KKK44133.1 - 2.7e-24 85.4 0.3 5.3e-24 84.5 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KKK44133.1 - 1.9e-06 27.2 0.0 4.9e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KKK44133.1 - 0.00013 22.1 0.2 0.00027 21.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KKK44133.1 - 0.00055 19.9 0.4 0.0012 18.7 0.4 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KKK44133.1 - 0.00079 18.9 0.2 0.05 12.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK44133.1 - 0.0022 17.3 0.2 0.014 14.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK44133.1 - 0.057 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Response_reg PF00072.24 KKK44134.1 - 1.4e-25 89.7 1.1 1.5e-25 89.5 1.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain RNase_H_2 PF13482.6 KKK44136.1 - 6.1e-28 97.9 2.0 1.3e-27 96.8 2.0 1.6 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo1 PF03104.19 KKK44136.1 - 0.00021 20.5 3.9 0.00054 19.2 3.9 1.8 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 KKK44136.1 - 0.00099 18.8 0.2 0.0019 17.9 0.2 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Thiolase_N PF00108.23 KKK44137.1 - 5.7e-06 25.9 0.0 8.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK44137.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain OB_aCoA_assoc PF01796.17 KKK44138.1 - 0.0029 17.6 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 KKK44138.1 - 0.003 17.4 0.3 3.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) BKACE PF05853.12 KKK44139.1 - 2.5e-83 279.6 0.0 2.8e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme Dus PF01207.17 KKK44139.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) adh_short PF00106.25 KKK44140.1 - 5.5e-50 169.5 1.2 6.8e-50 169.2 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK44140.1 - 1.1e-39 136.5 0.0 1.5e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK44140.1 - 4.3e-09 36.5 0.1 5.6e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KKK44140.1 - 0.009 15.4 0.5 0.013 14.9 0.5 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KKK44140.1 - 0.028 13.6 0.2 0.047 12.8 0.2 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DrrA_P4M PF14860.6 KKK44140.1 - 0.32 10.9 3.7 1.9 8.4 1.1 2.6 2 1 1 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain OB_aCoA_assoc PF01796.17 KKK44141.1 - 2.2e-07 30.8 0.0 3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 KKK44141.1 - 2.6e-07 30.4 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zf_UBZ PF18439.1 KKK44141.1 - 0.028 14.0 2.6 3.2 7.4 0.2 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KKK44141.1 - 0.043 13.8 0.4 0.067 13.2 0.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 KKK44141.1 - 0.095 12.6 2.0 0.86 9.6 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain YhfH PF14149.6 KKK44141.1 - 0.55 10.3 3.2 3.2 7.8 0.2 2.4 2 0 0 2 2 2 0 YhfH-like protein zf-ribbon_3 PF13248.6 KKK44141.1 - 0.86 9.1 5.1 2 8.0 5.1 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.26 KKK44141.1 - 1.6 9.3 5.4 2.1 8.9 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Thiolase_N PF00108.23 KKK44142.1 - 2.3e-06 27.2 0.0 7.9e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK44142.1 - 0.0012 18.5 2.3 0.011 15.4 0.7 2.7 2 1 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 KKK44143.1 - 1.8e-07 30.8 0.2 2.6e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain DUF35_N PF12172.8 KKK44144.1 - 2.5e-06 27.2 0.1 4e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) OB_aCoA_assoc PF01796.17 KKK44144.1 - 0.00038 20.4 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated Beta_elim_lyase PF01212.21 KKK44146.1 - 1.8e-81 273.6 0.0 2.2e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KKK44146.1 - 1.7e-10 40.7 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KKK44146.1 - 1.4e-07 31.2 0.0 7e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KKK44146.1 - 0.00016 20.4 0.0 0.0008 18.0 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKK44146.1 - 0.00032 19.8 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF362 PF04015.12 KKK44147.1 - 5.1e-35 121.6 2.2 6e-35 121.3 2.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF362) ECF-ribofla_trS PF07155.12 KKK44149.1 - 1.9e-05 24.7 16.5 5.5e-05 23.2 16.5 1.6 1 1 0 1 1 1 1 ECF-type riboflavin transporter, S component ECF_trnsprt PF12822.7 KKK44149.1 - 0.00028 21.0 27.6 0.0024 18.0 27.7 2.1 1 1 0 1 1 1 1 ECF transporter, substrate-specific component EVI2A PF05399.11 KKK44150.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.0 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) ETRAMP PF09716.10 KKK44150.1 - 0.012 15.7 0.0 0.012 15.7 0.0 1.0 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4711 PF15829.5 KKK44150.1 - 0.04 13.9 0.0 0.04 13.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) DUF3899 PF13038.6 KKK44150.1 - 0.048 14.2 0.0 0.05 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF2207 PF09972.9 KKK44150.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_US9 PF06072.11 KKK44150.1 - 0.44 10.5 3.1 0.59 10.1 3.1 1.4 1 1 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ribosomal_L27A PF00828.19 KKK44151.1 - 2.8e-16 60.3 1.1 3.3e-16 60.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AIRS PF00586.24 KKK44153.1 - 2.3e-13 50.6 0.0 3.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain TFIIB PF00382.19 KKK44155.1 - 1.9e-30 104.7 0.2 1.3e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KKK44155.1 - 1.6e-06 27.5 1.8 4.3e-06 26.1 1.8 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KKK44155.1 - 1.1e-05 25.5 0.7 0.00045 20.3 0.1 2.6 3 0 0 3 3 3 1 Retinoblastoma-associated protein B domain DZR PF12773.7 KKK44155.1 - 0.0013 18.7 0.3 0.0042 17.1 0.3 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK44155.1 - 0.006 16.3 1.9 0.1 12.3 0.3 2.7 2 0 0 2 2 2 1 zinc-ribbon domain zf-NADH-PPase PF09297.11 KKK44155.1 - 0.0081 15.8 2.1 0.022 14.4 2.1 1.8 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Cyclin_N PF00134.23 KKK44155.1 - 0.014 15.2 0.2 2.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain HTH_3 PF01381.22 KKK44155.1 - 0.044 13.8 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4_2 PF08281.12 KKK44155.1 - 0.055 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Rrf2 PF02082.20 KKK44155.1 - 0.1 13.0 0.1 3.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator OrfB_Zn_ribbon PF07282.11 KKK44155.1 - 0.11 12.4 0.5 0.27 11.2 0.5 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain TFIIB_C_1 PF18542.1 KKK44155.1 - 0.12 12.4 0.1 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 HTH_AsnC-type PF13404.6 KKK44155.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Cyclin_C PF02984.19 KKK44155.1 - 0.14 12.3 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain zf-ribbon_3 PF13248.6 KKK44155.1 - 0.27 10.7 4.1 3.7 7.1 0.3 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KKK44155.1 - 1.7 8.6 7.1 12 5.9 5.8 2.8 2 1 0 2 2 2 0 Nudix N-terminal A2L_zn_ribbon PF08792.10 KKK44155.1 - 2.4 8.0 7.4 4.1 7.2 3.4 2.8 2 1 0 2 2 2 0 A2L zinc ribbon domain Response_reg PF00072.24 KKK44156.1 - 6.2e-18 65.0 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKK44156.1 - 1.5e-06 28.1 0.1 2.9e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF2294 PF10057.9 KKK44156.1 - 0.076 13.1 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) DUF749 PF05370.11 KKK44156.1 - 0.4 10.8 4.0 1.5 9.0 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF749) Response_reg PF00072.24 KKK44157.1 - 1.2e-18 67.3 0.0 2.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKK44157.1 - 1.2e-05 25.3 0.1 2.7e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF1951 PF09188.10 KKK44157.1 - 0.1 12.6 2.3 0.072 13.1 0.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1951) Prok-JAB PF14464.6 KKK44158.1 - 0.00047 19.9 0.0 0.0006 19.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Toxin-JAB1 PF15659.6 KKK44158.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 JAB-like toxin 1 Acyl_transf_3 PF01757.22 KKK44159.1 - 1.5e-11 44.0 52.1 2e-11 43.6 52.1 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF3681 PF12442.8 KKK44159.1 - 0.0041 17.6 0.9 0.054 14.0 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3681) Putative_PNPOx PF01243.20 KKK44160.1 - 1.6e-05 25.0 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KKK44160.1 - 0.0015 18.1 0.1 0.0017 18.0 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like DUF2856 PF11043.8 KKK44160.1 - 0.28 11.3 3.1 8.6 6.5 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2856) Nore1-SARAH PF16517.5 KKK44160.1 - 0.71 9.8 6.7 2.9 7.9 0.2 2.3 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF5095 PF17016.5 KKK44161.1 - 0.0086 15.8 0.7 0.0096 15.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5095) Radical_SAM PF04055.21 KKK44162.1 - 4.3e-09 37.0 0.0 7.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 KKK44162.1 - 1.4e-07 31.6 0.0 5.5e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 B12 binding domain Methyltransf_23 PF13489.6 KKK44163.1 - 2.9e-06 27.2 0.0 4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK44163.1 - 5.4e-06 27.0 0.0 8.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK44163.1 - 4.6e-05 24.0 0.0 6.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK44163.1 - 0.003 17.4 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK44163.1 - 0.07 13.9 0.0 0.15 12.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF2110 PF09883.9 KKK44164.1 - 2.9e-31 108.8 0.0 3.3e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2110) DUF1289 PF06945.13 KKK44164.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Pox_D5 PF03288.16 KKK44164.1 - 0.2 12.2 1.7 7 7.2 0.1 2.5 2 0 0 2 2 2 0 Poxvirus D5 protein-like Profilin PF00235.19 KKK44165.1 - 0.0027 18.0 0.0 0.0034 17.7 0.0 1.1 1 0 0 1 1 1 1 Profilin dCache_1 PF02743.18 KKK44165.1 - 0.0054 16.6 0.1 0.006 16.4 0.1 1.1 1 0 0 1 1 1 1 Cache domain Robl_LC7 PF03259.17 KKK44165.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain Proteasome PF00227.26 KKK44166.1 - 2.9e-54 183.5 0.0 3.7e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK44166.1 - 2.1e-13 49.6 0.1 4.2e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SBDS_C PF09377.10 KKK44167.1 - 3.6e-21 75.3 3.9 5.8e-21 74.7 3.9 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KKK44167.1 - 1e-09 38.4 1.5 1.2e-09 38.1 0.2 1.9 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF5342 PF17277.2 KKK44167.1 - 0.03 14.6 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5342) KH_6 PF15985.5 KKK44168.1 - 6.1e-06 26.5 0.1 1e-05 25.8 0.1 1.3 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 KKK44168.1 - 1.6e-05 24.7 1.3 4.1e-05 23.3 1.3 1.7 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 KKK44168.1 - 4.5e-05 23.1 0.0 9.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_4 PF13083.6 KKK44168.1 - 0.00063 19.6 0.3 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 KKK44168.1 - 0.0014 18.4 0.2 0.0036 17.1 0.2 1.7 1 0 0 1 1 1 1 KH domain Inhibitor_I78 PF11720.8 KKK44168.1 - 0.13 12.4 0.1 6.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I78 family RNase_PH PF01138.21 KKK44169.1 - 2.1e-28 99.4 0.0 2.8e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK44169.1 - 6.5e-10 38.9 0.1 1.1e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CPT_N PF16484.5 KKK44169.1 - 0.21 11.6 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus RNase_PH PF01138.21 KKK44170.1 - 7.1e-18 65.4 0.0 1.1e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK44170.1 - 6.3e-10 39.0 0.1 1.2e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Jacalin PF01419.17 KKK44170.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain Ribosomal_L37ae PF01780.19 KKK44171.1 - 1e-26 92.8 6.5 1.2e-26 92.6 6.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KKK44171.1 - 2e-05 24.4 1.5 2e-05 24.4 1.5 1.9 2 1 0 2 2 2 1 Transposase zinc-ribbon domain HypA PF01155.19 KKK44171.1 - 0.00059 19.8 0.0 0.00082 19.4 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_S27e PF01667.17 KKK44171.1 - 0.021 14.5 0.3 0.033 13.9 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 zinc_ribbon_4 PF13717.6 KKK44171.1 - 0.027 14.4 4.8 1.1 9.3 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain Rep_fac-A_C PF08646.10 KKK44171.1 - 0.03 14.1 0.3 0.041 13.6 0.3 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-HIT PF04438.16 KKK44171.1 - 0.06 13.2 1.4 4.2 7.3 0.2 2.3 2 0 0 2 2 2 0 HIT zinc finger Zn-ribbon_8 PF09723.10 KKK44171.1 - 0.07 13.3 0.5 8.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Endonuclease_7 PF02945.15 KKK44171.1 - 0.089 12.7 1.4 0.21 11.5 1.3 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII zf-TFIIB PF13453.6 KKK44171.1 - 0.17 11.3 1.7 0.33 10.3 1.7 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-Dof PF02701.15 KKK44171.1 - 0.21 11.7 4.6 2.8 8.1 4.6 2.2 1 1 0 1 1 1 0 Dof domain, zinc finger zf-RanBP PF00641.18 KKK44171.1 - 0.25 10.7 4.0 0.8 9.1 0.8 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Prefoldin_2 PF01920.20 KKK44173.1 - 1e-15 57.6 15.4 1.2e-15 57.4 15.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit LRRFIP PF09738.9 KKK44173.1 - 0.0091 15.5 10.8 0.01 15.3 10.8 1.0 1 0 0 1 1 1 1 LRRFIP family BING4CT PF08149.11 KKK44173.1 - 0.85 9.5 3.8 13 5.6 0.2 2.2 2 0 0 2 2 2 0 BING4CT (NUC141) domain TPR_MLP1_2 PF07926.12 KKK44173.1 - 1.2 9.2 14.2 0.36 10.9 5.8 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DHH PF01368.20 KKK44174.1 - 1.5e-08 34.8 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 KKK44174.1 - 3.3e-07 30.8 0.1 6.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 DHHA1 domain Ribosomal_L5_C PF00673.21 KKK44174.1 - 0.036 14.2 0.1 0.082 13.1 0.1 1.6 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Atg8 PF02991.16 KKK44174.1 - 0.045 13.9 0.4 0.12 12.5 0.2 1.8 2 0 0 2 2 2 0 Autophagy protein Atg8 ubiquitin like ABC_tran PF00005.27 KKK44175.1 - 5.4e-25 88.5 0.0 7.9e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK44175.1 - 3.8e-11 43.3 1.7 2.1e-06 27.8 0.5 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK44175.1 - 1.3e-08 34.6 0.1 2.6e-08 33.6 0.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK44175.1 - 5.7e-05 23.4 1.1 0.0041 17.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KKK44175.1 - 0.00017 22.2 3.0 0.00034 21.2 3.1 1.6 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KKK44175.1 - 0.002 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_15 PF13175.6 KKK44175.1 - 0.002 17.9 3.4 0.021 14.6 0.3 2.2 2 0 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 KKK44175.1 - 0.0035 16.8 0.6 0.069 12.6 0.2 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_29 PF13555.6 KKK44175.1 - 0.0099 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DEAD PF00270.29 KKK44175.1 - 0.01 15.6 0.1 0.043 13.6 0.1 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase G-alpha PF00503.20 KKK44175.1 - 0.012 14.8 0.3 0.019 14.1 0.3 1.5 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 KKK44175.1 - 0.018 15.5 0.0 0.024 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KKK44175.1 - 0.027 14.5 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 KKK44175.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 KKK44175.1 - 0.029 13.3 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 KKK44175.1 - 0.041 13.3 0.0 0.099 12.0 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KKK44175.1 - 0.1 11.9 1.6 1.7 8.0 1.6 2.2 1 1 0 1 1 1 0 KaiC AAA_7 PF12775.7 KKK44175.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KKK44175.1 - 0.15 12.3 0.0 2.7 8.3 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KKK44175.1 - 0.15 12.0 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 KKK44175.1 - 0.2 11.3 0.6 0.33 10.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK44176.1 - 5.3e-32 111.2 0.4 1.8e-31 109.5 0.2 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KKK44176.1 - 5.4e-12 46.1 5.0 3.1e-06 27.2 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK44176.1 - 1e-06 28.4 4.0 2.7e-06 27.0 4.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 KKK44176.1 - 6.5e-05 21.8 1.8 0.0082 14.8 0.2 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KKK44176.1 - 0.0024 17.8 0.1 0.0055 16.6 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KKK44176.1 - 0.0034 17.9 7.0 0.012 16.2 7.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK44176.1 - 0.0043 16.8 0.1 0.0083 15.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK44176.1 - 0.0051 17.2 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK44176.1 - 0.0066 16.2 0.1 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KKK44176.1 - 0.0072 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 KKK44176.1 - 0.0078 16.0 7.4 0.0078 16.0 7.4 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KKK44176.1 - 0.014 15.4 1.0 0.12 12.4 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK44176.1 - 0.032 14.8 0.7 0.094 13.3 0.7 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK44176.1 - 0.037 14.3 1.1 0.086 13.1 0.3 2.3 2 1 0 2 2 2 0 AAA domain DLIC PF05783.11 KKK44176.1 - 0.04 12.8 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Phage_int_SAM_4 PF13495.6 KKK44176.1 - 0.044 14.2 0.0 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain MMR_HSR1 PF01926.23 KKK44176.1 - 0.056 13.5 1.3 0.11 12.6 0.5 1.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 KKK44176.1 - 0.069 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KKK44176.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK44176.1 - 0.11 12.5 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 KKK44176.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KKK44176.1 - 0.15 12.0 0.9 6.4 6.7 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KKK44176.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 KKK44176.1 - 0.17 11.5 0.2 0.28 10.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKK44176.1 - 0.21 11.3 0.7 8.1 6.1 0.0 2.4 2 1 0 2 2 2 0 IstB-like ATP binding protein CbiQ PF02361.16 KKK44177.1 - 3.7e-26 92.1 15.3 3.7e-26 92.1 15.3 2.8 2 1 0 2 2 2 1 Cobalt transport protein CGI-121 PF08617.10 KKK44178.1 - 8.2e-10 39.0 2.6 1.2e-09 38.5 2.6 1.3 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF4061 PF13270.6 KKK44178.1 - 0.11 12.8 1.8 4.4 7.7 1.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) Peptidase_C74 PF12387.8 KKK44178.1 - 0.21 11.1 4.4 0.4 10.1 0.5 2.1 1 1 1 2 2 2 0 Pestivirus NS2 peptidase THUMP PF02926.17 KKK44179.1 - 4.8e-12 46.2 5.4 6.5e-12 45.8 5.4 1.2 1 0 0 1 1 1 1 THUMP domain FF PF01846.19 KKK44179.1 - 0.04 14.1 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 FF domain Sua5_yciO_yrdC PF01300.18 KKK44180.1 - 1.2e-43 148.7 0.0 1.4e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination TPP_enzyme_C PF02775.21 KKK44181.1 - 1.7e-21 76.6 0.0 4.8e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 KKK44182.1 - 1.7e-59 201.4 0.7 2.3e-59 200.9 0.7 1.1 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KKK44182.1 - 1.2e-25 89.7 0.1 2.1e-25 89.0 0.1 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KKK44182.1 - 4.6e-05 23.3 0.0 9.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Haem_bd PF14376.6 KKK44182.1 - 0.19 11.7 0.0 0.45 10.5 0.0 1.6 2 0 0 2 2 2 0 Haem-binding domain Fer4 PF00037.27 KKK44183.1 - 6.6e-10 38.4 14.9 1.9e-05 24.2 3.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK44183.1 - 8.4e-09 35.9 20.2 3.2e-06 27.6 9.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44183.1 - 5e-08 33.8 13.2 0.00033 21.5 2.9 2.7 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK44183.1 - 2.8e-07 30.6 9.9 4.6e-07 29.9 9.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK44183.1 - 2.8e-06 27.4 7.0 4.4e-06 26.7 7.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK44183.1 - 3.2e-06 27.5 2.4 0.057 13.9 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK44183.1 - 2.9e-05 24.5 6.3 0.085 13.4 2.4 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK44183.1 - 0.00013 22.0 22.7 0.0039 17.3 3.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44183.1 - 0.00017 21.5 13.6 0.0086 16.1 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK44183.1 - 0.00088 19.2 11.1 0.02 15.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 KKK44183.1 - 0.02 15.4 7.1 0.53 10.9 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KKK44183.1 - 0.028 15.1 8.5 0.56 11.0 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 KKK44183.1 - 0.11 13.1 12.0 1.4 9.6 1.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK44183.1 - 0.12 13.3 1.6 0.12 13.3 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain POR PF01558.18 KKK44184.1 - 3.8e-22 79.2 0.0 4.5e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase zf-ZPR1 PF03367.13 KKK44185.1 - 1.9e-29 102.6 0.0 2.9e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 ZPR1 zinc-finger domain RNA_POL_M_15KD PF02150.16 KKK44185.1 - 0.018 14.9 1.5 0.17 11.8 0.1 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Surfac_D-trimer PF09006.11 KKK44185.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation zf-H2C2_2 PF13465.6 KKK44185.1 - 0.8 10.2 2.7 36 5.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain PFK PF00365.20 KKK44186.1 - 2.5e-85 286.3 0.0 3.5e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 KKK44186.1 - 0.0045 16.6 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 KKK44186.1 - 0.0098 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase Radical_SAM PF04055.21 KKK44187.1 - 4.3e-19 69.5 0.2 1.9e-18 67.4 0.3 2.0 2 0 0 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 KKK44187.1 - 9.3e-18 64.4 0.0 3.1e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 B12 binding domain Acyl-CoA_dh_1 PF00441.24 KKK44188.1 - 1.6e-33 116.1 0.1 2.8e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK44188.1 - 3e-24 85.9 0.0 8.9e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KKK44188.1 - 4.6e-18 65.8 0.0 7.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KKK44188.1 - 4.5e-16 58.8 0.0 7.4e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MFS_1 PF07690.16 KKK44189.1 - 4.8e-62 209.9 44.0 9.7e-41 139.8 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK44189.1 - 2.3e-11 43.2 29.2 1.8e-10 40.2 29.1 2.0 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 KKK44189.1 - 3.2e-10 39.0 15.3 3e-09 35.8 15.6 1.8 1 1 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 KKK44189.1 - 3.2e-08 32.9 39.5 2.2e-07 30.1 7.6 3.2 1 1 2 3 3 3 3 Sugar (and other) transporter Nuc_H_symport PF03825.16 KKK44189.1 - 0.0036 16.3 22.5 0.0095 15.0 22.5 1.7 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 KKK44189.1 - 1.3 7.7 30.8 3.8 6.2 30.7 1.8 1 1 0 1 1 1 0 LacY proton/sugar symporter Sld3_N PF18523.1 KKK44190.1 - 0.018 15.2 0.4 0.047 13.8 0.4 1.8 1 0 0 1 1 1 0 Sld3 N-terminal domain YppF PF14178.6 KKK44190.1 - 0.025 14.5 0.1 0.095 12.6 0.1 2.0 1 0 0 1 1 1 0 YppF-like protein GatB_Yqey PF02637.18 KKK44190.1 - 0.028 14.3 0.2 3.1 7.7 0.2 2.5 2 0 0 2 2 2 0 GatB domain zf-ribbon_3 PF13248.6 KKK44192.1 - 0.014 14.8 4.5 1.4 8.4 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_7 PF02591.15 KKK44192.1 - 0.043 14.0 0.7 9.5 6.5 0.1 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain CsgE PF10627.9 KKK44192.1 - 0.1 12.8 0.3 1.9 8.8 0.1 2.1 1 1 1 2 2 2 0 Curli assembly protein CsgE zf-C2HC5 PF06221.13 KKK44192.1 - 0.13 12.2 0.4 0.24 11.4 0.4 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zinc_ribbon_2 PF13240.6 KKK44192.1 - 0.22 11.3 6.0 3.1 7.6 1.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KKK44192.1 - 0.9 9.6 5.9 31 4.6 5.7 2.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain CpXC PF14353.6 KKK44192.1 - 4.4 7.4 5.2 8.2 6.5 0.2 3.1 1 1 2 3 3 3 0 CpXC protein FGGY_N PF00370.21 KKK44193.1 - 6.6e-72 242.0 0.0 1.1e-71 241.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KKK44193.1 - 2e-39 135.4 0.0 3e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KKK44193.1 - 0.0037 16.8 0.0 0.038 13.5 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MtrB PF05440.12 KKK44194.1 - 0.019 15.4 0.0 0.019 15.4 0.0 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Saf_2TM PF18303.1 KKK44194.1 - 0.026 14.1 9.9 0.087 12.4 0.3 3.1 3 1 0 3 3 3 0 SAVED-fused 2TM effector domain DUF2568 PF10823.8 KKK44194.1 - 1.9 8.8 11.2 0.081 13.2 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2568) CrgA PF06781.12 KKK44194.1 - 7.6 6.7 13.1 0.37 10.9 3.2 2.8 1 1 2 3 3 3 0 Cell division protein CrgA RtcB PF01139.17 KKK44201.1 - 6.7e-29 101.3 0.1 7.2e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB BBL5 PF07289.11 KKK44201.1 - 0.016 14.3 0.0 0.018 14.1 0.0 1.0 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein Archease PF01951.16 KKK44202.1 - 2.9e-40 137.7 1.1 3.2e-40 137.6 1.1 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) KH_2 PF07650.17 KKK44203.1 - 0.0063 16.3 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 KH domain CarS-like PF01864.17 KKK44204.1 - 1.3e-33 116.5 18.3 6e-21 75.2 6.5 2.5 2 1 1 3 3 3 2 CDP-archaeol synthase CTP_transf_1 PF01148.20 KKK44204.1 - 3e-05 23.9 0.3 3e-05 23.9 0.3 3.1 3 0 0 3 3 3 1 Cytidylyltransferase family Phage_holin_3_6 PF07332.11 KKK44204.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.9 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2157 PF09925.9 KKK44204.1 - 0.23 11.2 6.5 0.055 13.3 2.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) TMEM208_SND2 PF05620.11 KKK44204.1 - 3.3 7.5 5.7 0.4 10.4 0.4 2.2 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 AAA_16 PF13191.6 KKK44205.1 - 0.0037 17.7 0.0 0.0044 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Kinesin PF00225.23 KKK44205.1 - 0.018 14.0 0.2 0.018 14.0 0.2 1.3 1 1 0 1 1 1 0 Kinesin motor domain Microtub_bd PF16796.5 KKK44205.1 - 0.59 10.1 2.0 1.8 8.5 0.2 1.9 1 1 0 2 2 2 0 Microtubule binding NifU PF01106.17 KKK44207.1 - 8.6e-11 41.8 0.7 9.5e-11 41.7 0.7 1.1 1 0 0 1 1 1 1 NifU-like domain PCI PF01399.27 KKK44208.1 - 0.022 15.3 3.3 0.067 13.7 3.3 1.7 1 1 0 1 1 1 0 PCI domain Arf PF00025.21 KKK44209.1 - 3.2e-06 26.7 0.0 6.1e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK44209.1 - 1.1e-05 25.6 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKK44209.1 - 0.00023 20.6 0.1 0.00062 19.2 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KKK44209.1 - 0.00025 20.7 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK44209.1 - 0.00067 19.1 0.1 0.0013 18.2 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 KKK44209.1 - 0.051 13.3 0.2 0.08 12.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KKK44209.1 - 0.072 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Adenine_glyco PF03352.13 KKK44210.1 - 4.7e-81 270.8 0.3 5.5e-81 270.6 0.3 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase HhH-GPD PF00730.25 KKK44210.1 - 0.12 12.8 0.0 0.18 12.3 0.0 1.4 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DeoC PF01791.9 KKK44214.1 - 8.8e-54 182.6 0.0 1e-53 182.4 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase NMO PF03060.15 KKK44215.1 - 4.8e-40 137.9 2.0 9e-40 137.1 2.0 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK44215.1 - 3.1e-09 36.3 0.1 8.1e-09 34.9 0.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK44215.1 - 6e-06 25.5 2.0 1.1e-05 24.6 0.9 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase GTP_EFTU_D4 PF14578.6 KKK44215.1 - 0.026 14.4 0.4 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 HEAT_2 PF13646.6 KKK44216.1 - 2.4e-20 72.7 0.0 4.9e-13 49.3 0.0 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KKK44216.1 - 3.9e-12 45.3 0.0 0.017 15.3 0.0 3.3 3 0 0 3 3 3 3 HEAT repeat Cnd1 PF12717.7 KKK44216.1 - 2.2e-05 24.6 0.0 0.051 13.6 0.0 2.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 zf-ribbon_3 PF13248.6 KKK44216.1 - 2.7e-05 23.4 1.5 4.6e-05 22.7 1.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain HEAT_EZ PF13513.6 KKK44216.1 - 0.00017 22.0 0.0 0.29 11.7 0.0 3.0 1 1 2 3 3 3 2 HEAT-like repeat Cohesin_HEAT PF12765.7 KKK44216.1 - 0.00017 21.8 0.2 0.19 12.0 0.0 2.5 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion zinc_ribbon_2 PF13240.6 KKK44216.1 - 0.0002 20.9 2.2 0.00033 20.3 2.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK44216.1 - 0.00023 21.1 0.3 0.00038 20.4 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK44216.1 - 0.00062 20.5 0.5 0.00096 19.9 0.5 1.3 1 0 0 1 1 1 1 zinc-ribbon family HEAT_PBS PF03130.16 KKK44216.1 - 0.0012 19.3 0.0 3.2 8.7 0.0 3.2 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat UPF0547 PF10571.9 KKK44216.1 - 0.0038 17.3 1.6 0.0061 16.6 1.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 Adaptin_N PF01602.20 KKK44216.1 - 0.0069 15.0 0.0 0.014 14.0 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Arm PF00514.23 KKK44216.1 - 0.029 14.4 0.0 15 5.8 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Nipped-B_C PF12830.7 KKK44216.1 - 0.12 12.3 0.0 25 4.7 0.0 2.7 2 1 1 3 3 3 0 Sister chromatid cohesion C-terminus RasGEF_N_2 PF14663.6 KKK44216.1 - 0.14 12.6 0.0 6.1 7.3 0.0 2.8 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain zf_C2H2_13 PF18508.1 KKK44216.1 - 0.73 9.5 4.7 0.41 10.3 0.7 2.2 1 1 1 2 2 2 0 Zinc finger domain Gelsolin PF00626.22 KKK44217.1 - 0.00038 20.3 0.0 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat HC2 PF07382.11 KKK44217.1 - 0.00059 20.0 8.7 0.0014 18.8 8.7 1.5 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 LOR PF04525.12 KKK44218.1 - 3e-07 30.2 0.0 1.5e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 LURP-one-related Scramblase PF03803.15 KKK44218.1 - 0.0024 17.2 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 Scramblase DUF4539 PF15072.6 KKK44218.1 - 0.0042 17.1 0.0 2.8 8.1 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4539) zinc_ribbon_2 PF13240.6 KKK44219.1 - 1.9e-08 33.7 3.0 2.7e-08 33.3 3.0 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK44219.1 - 2e-05 24.5 0.7 2.5e-05 24.2 0.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK44219.1 - 0.00023 20.5 3.5 0.00053 19.3 3.2 1.7 1 1 1 2 2 2 2 zinc-ribbon domain Nudix_N_2 PF14803.6 KKK44219.1 - 0.00034 20.5 1.2 0.13 12.2 0.2 2.2 2 0 0 2 2 2 2 Nudix N-terminal NOB1_Zn_bind PF08772.11 KKK44219.1 - 0.0014 18.8 1.7 0.002 18.3 1.7 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf_UBZ PF18439.1 KKK44219.1 - 0.0048 16.5 5.0 0.056 13.0 0.8 2.3 1 1 1 2 2 2 1 Ubiquitin-Binding Zinc Finger DUF2116 PF09889.9 KKK44219.1 - 0.0075 16.2 2.8 0.013 15.5 2.8 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-dskA_traR PF01258.17 KKK44219.1 - 0.021 14.8 3.5 0.45 10.5 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger YhfH PF14149.6 KKK44219.1 - 0.023 14.7 6.7 0.21 11.6 0.7 2.2 1 1 1 2 2 2 0 YhfH-like protein zinc_ribbon_15 PF17032.5 KKK44219.1 - 0.034 14.9 1.3 0.051 14.3 1.3 1.5 1 0 0 1 1 1 0 zinc-ribbon family GFA PF04828.14 KKK44219.1 - 0.043 14.2 3.1 0.2 12.0 3.1 1.9 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme OrfB_Zn_ribbon PF07282.11 KKK44219.1 - 0.069 13.1 2.5 0.11 12.5 2.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2321 PF10083.9 KKK44219.1 - 0.091 12.4 1.4 0.17 11.5 1.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF2797 PF10977.8 KKK44219.1 - 0.16 11.8 1.1 0.17 11.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) NinF PF05810.12 KKK44219.1 - 0.17 11.8 1.1 0.23 11.4 1.1 1.3 1 0 0 1 1 1 0 NinF protein MqsA_antitoxin PF15731.5 KKK44219.1 - 0.2 11.8 1.9 0.39 10.8 0.5 1.9 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HypA PF01155.19 KKK44219.1 - 0.25 11.3 2.3 0.31 11.1 2.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KKK44219.1 - 0.78 9.9 4.2 2.7 8.2 4.2 1.8 1 1 0 1 1 1 0 Zinc ribbon domain CDP-OH_P_transf PF01066.21 KKK44220.1 - 3.6e-10 40.5 0.6 3.6e-10 40.5 0.6 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3262 PF11660.8 KKK44220.1 - 0.14 12.6 2.7 0.9 10.0 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3262) SOUL PF04832.12 KKK44221.1 - 0.016 15.4 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 SOUL heme-binding protein Baculo_PEP_C PF04513.12 KKK44221.1 - 0.017 15.1 31.7 0.52 10.3 6.2 6.0 2 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.12 KKK44221.1 - 0.028 14.4 6.8 1.9 8.5 0.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) eIF-5_eIF-2B PF01873.17 KKK44221.1 - 0.096 12.6 3.3 0.2 11.5 0.6 2.8 2 0 0 2 2 2 0 Domain found in IF2B/IF5 CLZ PF16526.5 KKK44221.1 - 4.3 7.8 9.9 4.4 7.7 0.4 4.1 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zinc_ribbon_15 PF17032.5 KKK44222.1 - 0.00016 22.3 1.1 0.00016 22.3 1.1 3.4 2 1 1 3 3 2 1 zinc-ribbon family zinc_ribbon_2 PF13240.6 KKK44222.1 - 0.00096 18.8 3.5 0.00096 18.8 3.5 3.1 4 0 0 4 4 4 1 zinc-ribbon domain HypA PF01155.19 KKK44222.1 - 0.0028 17.7 0.1 0.0028 17.7 0.1 3.1 2 1 0 2 2 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KKK44222.1 - 0.0063 16.5 2.2 0.0063 16.5 2.2 3.1 2 1 0 2 2 2 1 Double zinc ribbon DUF3387 PF11867.8 KKK44222.1 - 0.0071 15.8 0.3 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) DUF3189 PF11385.8 KKK44222.1 - 0.025 14.4 0.6 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3189) zinc_ribbon_5 PF13719.6 KKK44222.1 - 0.23 11.2 0.0 0.23 11.2 0.0 4.3 4 1 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.22 KKK44222.1 - 0.67 9.9 13.5 1.9 8.5 5.8 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PLATZ PF04640.14 KKK44222.1 - 0.7 10.5 6.5 1 10.0 1.8 2.7 2 0 0 2 2 2 0 PLATZ transcription factor zf-ANAPC11 PF12861.7 KKK44222.1 - 0.77 9.8 8.7 0.29 11.2 3.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cript PF10235.9 KKK44222.1 - 5.4 7.7 11.6 0.36 11.4 2.9 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-CHY PF05495.12 KKK44222.1 - 7.9 7.0 18.0 0.34 11.4 1.5 2.6 2 1 0 2 2 2 0 CHY zinc finger Bunya_nucleocap PF00952.17 KKK44223.1 - 0.0097 15.9 0.7 0.014 15.4 0.7 1.2 1 0 0 1 1 1 1 Bunyavirus nucleocapsid (N) protein UPF0258 PF06789.12 KKK44223.1 - 0.084 13.0 1.6 0.49 10.5 0.0 2.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0258) Spore_Cse60 PF10957.8 KKK44224.1 - 0.054 13.5 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein Cse60 VWA PF00092.28 KKK44225.1 - 7e-05 23.1 0.5 0.00011 22.5 0.5 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain zinc-ribbons_6 PF07191.12 KKK44225.1 - 0.043 13.8 0.2 0.043 13.8 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 KKK44225.1 - 0.34 10.4 17.6 2.5 7.6 3.0 4.4 4 0 0 4 4 4 0 zinc-ribbon domain Aminotran_3 PF00202.21 KKK44226.1 - 4.8e-53 180.3 0.0 7.4e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III TRP_2 PF08344.11 KKK44229.1 - 0.16 12.2 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Transient receptor ion channel II DUF998 PF06197.13 KKK44230.1 - 3.3e-12 46.4 11.2 4.4e-12 46.0 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF4231 PF14015.6 KKK44230.1 - 0.57 10.7 5.8 16 6.0 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) ABC_tran PF00005.27 KKK44231.1 - 1.6e-26 93.5 0.0 3.2e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK44231.1 - 8.4e-09 35.6 1.2 0.0007 19.5 0.0 2.8 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KKK44231.1 - 4.9e-05 23.9 4.2 0.00022 21.8 4.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KKK44231.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KKK44231.1 - 0.025 14.0 0.0 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK44231.1 - 0.044 14.1 0.1 0.66 10.2 0.1 2.5 2 1 0 3 3 3 0 AAA domain AAA PF00004.29 KKK44231.1 - 0.067 13.6 2.2 2.6 8.5 2.1 2.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KKK44231.1 - 0.099 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RsgA_GTPase PF03193.16 KKK44231.1 - 0.1 12.5 0.2 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase ABC2_membrane_2 PF12679.7 KKK44232.1 - 0.019 14.2 33.0 0.085 12.1 32.9 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KKK44232.1 - 6.5 6.7 41.8 0.34 10.9 32.5 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein DDE_Tnp_1 PF01609.21 KKK44235.1 - 6e-09 35.9 7.7 2.7e-08 33.7 7.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain Bombinin PF05298.11 KKK44235.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Bombinin DUF1661 PF07877.11 KKK44236.1 - 0.0066 16.1 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1661) Exo5 PF09810.9 KKK44237.1 - 2.4e-06 27.3 0.1 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease DUF3997 PF13162.6 KKK44238.1 - 0.023 15.0 1.5 0.032 14.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) NurA PF09376.10 KKK44240.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 NurA domain DUF87 PF01935.17 KKK44241.1 - 4.3e-07 30.3 0.0 1.9e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain SepF PF04472.12 KKK44241.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Cell division protein SepF RNase_Zc3h12a PF11977.8 KKK44242.1 - 0.082 12.7 0.2 0.17 11.6 0.2 1.6 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain SMC_N PF02463.19 KKK44243.1 - 6.3e-24 84.6 0.0 6.5e-23 81.3 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KKK44243.1 - 1.9e-14 54.7 5.7 1.9e-14 54.7 5.7 6.0 3 3 1 4 4 1 1 AAA domain AAA_29 PF13555.6 KKK44243.1 - 1.3e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KKK44243.1 - 2.9e-07 30.5 18.5 2.9e-07 30.5 18.5 5.5 3 2 2 5 5 1 1 AAA ATPase domain AAA_21 PF13304.6 KKK44243.1 - 1.2e-06 28.6 0.3 1.2e-06 28.6 0.3 5.0 3 2 1 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KKK44243.1 - 1.6e-06 28.7 3.4 0.075 13.6 0.1 3.9 3 0 0 3 3 3 2 ABC transporter AAA_27 PF13514.6 KKK44243.1 - 0.00045 19.9 0.1 0.00098 18.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain C1_1 PF00130.22 KKK44243.1 - 0.0036 17.1 1.0 0.0081 16.0 1.0 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KKK44243.1 - 0.029 14.7 3.9 0.07 13.5 3.9 1.6 1 0 0 1 1 1 0 C1 domain AAA PF00004.29 KKK44243.1 - 0.041 14.3 4.1 0.15 12.5 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 KKK44243.1 - 0.042 13.7 1.1 0.2 11.4 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_16 PF13191.6 KKK44243.1 - 0.056 13.8 0.0 0.29 11.5 0.0 2.2 3 0 0 3 3 2 0 AAA ATPase domain AAA_22 PF13401.6 KKK44243.1 - 0.081 13.2 0.0 0.55 10.5 0.0 2.5 3 0 0 3 3 1 0 AAA domain EF-hand_6 PF13405.6 KKK44243.1 - 0.082 12.9 0.1 0.58 10.2 0.1 2.6 1 0 0 1 1 1 0 EF-hand domain AAA_11 PF13086.6 KKK44243.1 - 0.11 12.3 2.3 0.3 10.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KKK44243.1 - 0.2 11.0 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KKK44243.1 - 0.51 10.2 2.9 3.4 7.5 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase HDV_ag PF01517.18 KKK44243.1 - 2.8 7.7 5.9 5.8 6.7 0.1 2.7 3 0 0 3 3 3 0 Hepatitis delta virus delta antigen S1_2 PF13509.6 KKK44244.1 - 0.059 13.4 0.0 0.43 10.7 0.0 2.1 1 1 1 2 2 2 0 S1 domain DUF2318 PF10080.9 KKK44245.1 - 0.0051 16.9 0.5 0.0056 16.8 0.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) Ribosomal_S27e PF01667.17 KKK44245.1 - 0.1 12.3 1.7 0.16 11.7 1.7 1.2 1 0 0 1 1 1 0 Ribosomal protein S27 Radical_SAM PF04055.21 KKK44248.1 - 5.6e-11 43.1 0.1 1.1e-10 42.1 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK44248.1 - 5.8e-09 36.3 0.2 1.6e-08 34.9 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK44248.1 - 2.7e-06 27.5 1.9 6.3e-06 26.3 1.1 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain RseC_MucC PF04246.12 KKK44251.1 - 0.89 9.5 8.5 1.3 9.0 1.4 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2070 PF09843.9 KKK44251.1 - 8.4 4.5 7.5 8.6 4.5 7.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RHH_1 PF01402.21 KKK44253.1 - 3.7e-08 33.0 0.0 9.9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family RHH_8 PF17723.1 KKK44253.1 - 1.7e-05 24.9 0.0 1.9e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family DZR PF12773.7 KKK44254.1 - 0.0021 18.0 0.1 0.0044 17.0 0.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon Bacillus_HBL PF05791.11 KKK44254.1 - 0.0079 16.0 3.4 0.035 13.9 2.0 2.1 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) zinc_ribbon_2 PF13240.6 KKK44254.1 - 0.033 13.9 1.2 0.086 12.6 1.2 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK44254.1 - 0.065 12.7 1.5 0.14 11.6 1.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain PEX11 PF05648.14 KKK44254.1 - 0.2 11.1 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) zf-C3HC4_3 PF13920.6 KKK44254.1 - 1.6 8.7 3.8 0.5 10.3 0.9 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Arf PF00025.21 KKK44255.1 - 2.6e-30 105.2 0.1 4.6e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK44255.1 - 3.7e-17 62.4 0.1 6.2e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK44255.1 - 2.9e-11 43.1 0.0 6.2e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK44255.1 - 4.4e-11 43.0 0.0 8.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KKK44255.1 - 4.4e-08 32.9 0.0 1.2e-07 31.5 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KKK44255.1 - 1.4e-07 31.1 8.8 1.1e-05 24.8 7.8 3.1 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 KKK44255.1 - 1.2e-06 28.1 0.1 1.2e-06 28.1 0.1 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK44255.1 - 1.6e-06 28.1 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase V4R PF02830.18 KKK44256.1 - 4.9e-06 26.5 0.5 1.9e-05 24.6 0.1 2.0 2 0 0 2 2 2 1 V4R domain MetOD1 PF18546.1 KKK44256.1 - 0.0012 18.9 0.2 0.0029 17.6 0.2 1.7 1 1 0 1 1 1 1 Metanogen output domain 1 HATPase_c PF02518.26 KKK44257.1 - 4.1e-23 82.0 0.2 1.1e-22 80.6 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KKK44257.1 - 5.9e-21 74.7 0.8 2.4e-15 56.6 0.1 2.4 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 KKK44257.1 - 2.4e-15 56.3 1.2 4.7e-14 52.2 0.2 2.6 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KKK44257.1 - 9.7e-14 51.3 0.0 1.1e-08 35.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KKK44257.1 - 4.7e-13 48.8 0.0 1.3e-10 41.1 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 KKK44257.1 - 1.1e-07 32.0 0.1 1.3e-05 25.3 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 KKK44257.1 - 2.4e-07 31.0 0.0 7.8e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 PAS fold PAS_7 PF12860.7 KKK44257.1 - 0.00043 20.4 0.0 0.027 14.6 0.0 2.7 2 1 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 KKK44257.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF1295 PF06966.12 KKK44259.1 - 4.1e-06 26.5 2.5 9.5e-06 25.3 2.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KKK44259.1 - 7.4e-06 26.3 2.1 1.2e-05 25.7 2.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KKK44259.1 - 7.4e-05 23.1 9.9 0.00086 19.7 7.8 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 KKK44259.1 - 0.0036 17.3 3.9 0.0036 17.3 3.9 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase TrkH PF02386.16 KKK44259.1 - 0.045 12.2 2.5 0.054 11.9 2.5 1.1 1 0 0 1 1 1 0 Cation transport protein DctQ PF04290.12 KKK44259.1 - 0.047 13.6 2.0 0.066 13.1 2.0 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3593 PF12159.8 KKK44259.1 - 0.48 10.5 10.0 0.087 12.9 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3593) SH PF01445.17 KKK44259.1 - 0.58 10.2 9.8 0.96 9.5 0.3 2.3 2 0 0 2 2 2 0 Viral small hydrophobic protein Hexokinase_1 PF00349.21 KKK44260.1 - 0.039 13.8 0.6 0.049 13.5 0.6 1.2 1 1 0 1 1 1 0 Hexokinase TssO PF17561.2 KKK44263.1 - 0.0026 17.9 1.3 0.0026 17.9 1.3 1.8 1 1 1 2 2 2 1 Type VI secretion system, TssO FlaC_arch PF05377.11 KKK44263.1 - 0.025 14.9 1.5 0.054 13.9 1.5 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KKK44263.1 - 0.026 14.3 1.6 0.049 13.4 1.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Rop-like PF05082.13 KKK44263.1 - 0.13 12.1 1.8 1.7 8.5 1.3 2.3 2 0 0 2 2 2 0 Rop-like CENP-H PF05837.12 KKK44263.1 - 0.18 12.3 3.0 0.22 12.0 3.0 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TMPIT PF07851.13 KKK44263.1 - 1.1 8.5 4.7 1.3 8.2 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein FAD_binding_4 PF01565.23 KKK44267.1 - 7.8e-35 119.6 2.1 1.2e-34 119.1 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain Mt_ATP_synt PF15704.5 KKK44267.1 - 0.059 13.3 0.3 0.1 12.5 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit DUF4386 PF14329.6 KKK44268.1 - 6.6e-23 81.7 12.3 8.1e-23 81.4 12.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) Thiolase_N PF00108.23 KKK44269.1 - 7.3e-15 55.0 8.4 8.8e-14 51.5 3.6 2.9 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK44269.1 - 7e-12 45.1 0.3 3.8e-11 42.7 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.22 KKK44269.1 - 0.00073 19.5 0.1 0.38 10.8 0.0 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.10 KKK44269.1 - 0.0032 17.3 0.3 0.47 10.3 0.2 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KKK44269.1 - 0.016 14.8 0.7 0.036 13.6 0.6 1.6 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain IU_nuc_hydro PF01156.19 KKK44270.1 - 9.9e-14 51.6 0.0 1.5e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FAD_binding_3 PF01494.19 KKK44271.1 - 2.6e-09 36.8 0.3 0.0011 18.3 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KKK44271.1 - 9.2e-07 28.5 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK44271.1 - 1.3e-06 27.8 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KKK44271.1 - 3.1e-06 26.6 2.4 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK44271.1 - 4.1e-06 26.3 1.5 1.6e-05 24.3 0.8 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KKK44271.1 - 4.9e-06 25.7 0.0 0.008 15.1 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 KKK44271.1 - 8.5e-06 25.1 0.0 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KKK44271.1 - 9.5e-06 24.9 0.0 0.029 13.4 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KKK44271.1 - 7.9e-05 21.5 3.2 0.00029 19.7 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 KKK44271.1 - 0.00056 19.2 0.1 0.00089 18.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KKK44271.1 - 0.0015 18.2 1.5 0.017 14.7 0.5 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK44271.1 - 0.011 15.9 0.1 0.022 15.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain BLOC1_2 PF10046.9 KKK44272.1 - 0.71 10.2 12.4 0.12 12.6 6.3 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 KKK44272.1 - 3.2 7.0 9.6 1.6 8.0 4.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) GIT_CC PF16559.5 KKK44272.1 - 3.4 7.6 8.2 0.73 9.8 3.0 2.4 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor AMP-binding_C PF13193.6 KKK44273.1 - 4.1e-11 43.7 0.0 5.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KKK44273.1 - 1.8e-09 36.7 1.1 2.7e-09 36.1 1.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Beta_helix PF13229.6 KKK44274.1 - 7.7e-32 110.3 98.4 4.9e-17 62.2 27.9 2.5 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 KKK44274.1 - 1.4e-27 96.5 68.1 2.8e-20 72.6 36.0 2.7 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 KKK44274.1 - 0.017 15.0 1.5 0.017 15.0 1.5 3.4 1 1 1 3 3 3 0 Pectate lyase superfamily protein Nudix_N_2 PF14803.6 KKK44275.1 - 0.00011 22.1 2.0 0.083 12.8 0.5 2.4 2 0 0 2 2 2 2 Nudix N-terminal DZR PF12773.7 KKK44275.1 - 0.00017 21.5 1.3 0.00029 20.8 1.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK44275.1 - 0.0012 18.5 8.8 0.12 12.2 1.0 2.3 2 0 0 2 2 2 2 zinc-ribbon domain YhfH PF14149.6 KKK44275.1 - 0.16 12.0 1.9 12 6.0 0.1 2.3 2 0 0 2 2 2 0 YhfH-like protein zf-B_box PF00643.24 KKK44275.1 - 0.16 12.1 0.5 10 6.4 0.0 2.1 2 0 0 2 2 2 0 B-box zinc finger zf-ribbon_3 PF13248.6 KKK44275.1 - 0.3 10.6 7.3 1.8 8.1 7.3 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zf_C2H2_13 PF18508.1 KKK44275.1 - 1 9.0 4.9 4 7.1 0.7 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-CCHC_4 PF14392.6 KKK44275.1 - 2.6 7.9 4.4 15 5.4 0.1 3.1 3 0 0 3 3 3 0 Zinc knuckle SurA_N_2 PF13623.6 KKK44276.1 - 0.0044 16.9 0.3 0.0048 16.8 0.3 1.0 1 0 0 1 1 1 1 SurA N-terminal domain AMP-binding PF00501.28 KKK44277.1 - 3.9e-19 68.5 0.0 4.3e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Flavodoxin_5 PF12724.7 KKK44278.1 - 1.7e-11 44.6 0.0 2.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 KKK44278.1 - 3.4e-07 30.1 0.0 4.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 KKK44278.1 - 1.3e-06 28.7 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.15 KKK44278.1 - 0.00018 21.3 0.0 0.00093 19.0 0.0 1.9 1 1 1 2 2 2 1 NADPH-dependent FMN reductase QCR10 PF09796.9 KKK44278.1 - 0.053 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) FAD_binding_4 PF01565.23 KKK44279.1 - 6.8e-37 126.3 0.9 1.2e-36 125.5 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S4 PF00163.19 KKK44279.1 - 0.0033 18.3 0.0 0.012 16.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Rubrerythrin PF02915.17 KKK44280.1 - 3.6e-17 63.1 0.1 5.2e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 Rubrerythrin zf-ribbon_3 PF13248.6 KKK44280.1 - 0.019 14.4 2.9 2 8.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KKK44280.1 - 0.03 14.5 0.7 0.062 13.4 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KKK44280.1 - 0.037 13.5 0.5 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Ferritin PF00210.24 KKK44280.1 - 0.068 13.1 0.1 0.43 10.5 0.1 2.0 1 1 0 1 1 1 0 Ferritin-like domain zf-H2C2_2 PF13465.6 KKK44280.1 - 0.076 13.5 1.2 16 6.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Rubredoxin PF00301.20 KKK44280.1 - 0.088 12.8 2.0 2.4 8.2 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin DNA_ligase_ZBD PF03119.16 KKK44280.1 - 0.92 9.6 3.0 3.1 7.9 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF2752 PF10825.8 KKK44280.1 - 1.1 9.4 3.6 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zinc_ribbon_2 PF13240.6 KKK44280.1 - 6 6.7 7.5 28 4.6 2.0 2.2 1 1 0 1 1 1 0 zinc-ribbon domain EutA PF06277.11 KKK44281.1 - 8.5e-129 430.5 0.3 1.2e-128 430.0 0.3 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA MreB_Mbl PF06723.13 KKK44281.1 - 0.00037 19.4 0.3 0.00067 18.6 0.3 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 KKK44281.1 - 0.0035 17.7 3.8 0.013 15.9 0.6 2.8 2 2 0 2 2 2 1 Cell division protein FtsA Jacalin PF01419.17 KKK44281.1 - 0.31 11.0 1.6 1.7 8.6 0.3 2.4 2 0 0 2 2 2 0 Jacalin-like lectin domain Sulfatase PF00884.23 KKK44282.1 - 2.6e-57 194.6 0.0 3.5e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK44282.1 - 1.4e-09 38.0 0.1 1.7e-08 34.5 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KKK44282.1 - 5.8e-06 26.5 0.4 8.9e-05 22.7 0.4 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 KKK44282.1 - 0.0004 19.8 0.0 0.002 17.5 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase_C PF14707.6 KKK44282.1 - 0.0026 18.5 0.0 0.0063 17.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4994 PF16385.5 KKK44282.1 - 0.0064 16.4 0.2 0.015 15.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF229 PF02995.17 KKK44282.1 - 0.03 12.9 0.0 0.039 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) ADH_zinc_N_2 PF13602.6 KKK44283.1 - 4e-21 76.5 0.0 6.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK44283.1 - 3.7e-11 43.1 0.0 3.1e-10 40.1 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK44283.1 - 1.8e-05 24.5 0.0 3.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KKK44283.1 - 0.0016 17.8 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KKK44283.1 - 0.0069 16.9 0.4 0.13 12.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KKK44283.1 - 0.021 14.1 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DapB_N PF01113.20 KKK44283.1 - 0.12 12.5 0.1 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N_2 PF13602.6 KKK44284.1 - 6.2e-29 101.7 0.0 9.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KKK44284.1 - 1.1e-17 64.2 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK44284.1 - 1.3e-09 37.9 0.0 5e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 KKK44284.1 - 0.0033 17.6 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.21 KKK44284.1 - 0.0051 16.1 0.1 0.0081 15.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.12 KKK44284.1 - 0.014 16.0 0.0 0.049 14.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain ADH_N_2 PF16884.5 KKK44284.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Methyltransf_12 PF08242.12 KKK44284.1 - 0.068 13.9 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KKK44284.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MazE_antitoxin PF04014.18 KKK44285.1 - 0.00027 20.8 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin SymE_toxin PF08845.10 KKK44285.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system PIN PF01850.21 KKK44286.1 - 2.6e-05 24.7 0.2 4.5e-05 23.9 0.2 1.4 1 1 0 1 1 1 1 PIN domain Paramyxo_P PF01806.17 KKK44286.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region DUF86 PF01934.17 KKK44287.1 - 3e-18 65.8 0.9 5.9e-18 64.9 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF86 MinE PF03776.14 KKK44287.1 - 0.08 13.0 1.2 0.36 10.9 0.2 2.2 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE Polbeta PF18765.1 KKK44288.1 - 1.9e-10 40.7 1.6 5.1e-10 39.3 0.1 2.0 1 1 1 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK44288.1 - 3.2e-06 27.3 0.1 4.8e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 Nucleotidyltransferase domain Fibroin_P25 PF07294.11 KKK44288.1 - 0.015 15.4 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 Fibroin P25 DUF4258 PF14076.6 KKK44289.1 - 0.066 13.6 0.0 0.093 13.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4258) Histone_HNS PF00816.21 KKK44289.1 - 0.085 13.7 0.2 0.096 13.5 0.2 1.1 1 0 0 1 1 1 0 H-NS histone family Rep_fac_C PF08542.11 KKK44289.1 - 0.14 12.6 0.1 0.14 12.5 0.1 1.1 1 0 0 1 1 1 0 Replication factor C C-terminal domain TAL_effector PF03377.13 KKK44289.1 - 0.17 12.2 0.0 0.5 10.7 0.0 1.8 2 0 0 2 2 2 0 TAL effector repeat MpPF1 PF07668.11 KKK44291.1 - 0.017 14.4 0.5 0.017 14.4 0.5 1.1 1 0 0 1 1 1 0 M penetrans paralogue family 1 nsp8 PF08717.10 KKK44291.1 - 0.03 14.2 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 nsp8 replicase RHH_3 PF12651.7 KKK44291.1 - 0.036 14.0 3.5 0.15 12.1 0.1 3.1 3 1 0 3 3 3 0 Ribbon-helix-helix domain DUF4252 PF14060.6 KKK44291.1 - 0.071 13.0 1.0 0.084 12.8 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) EF-1_beta_acid PF10587.9 KKK44291.1 - 0.08 13.4 1.7 0.08 13.4 1.7 1.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region DUF416 PF04222.12 KKK44291.1 - 0.092 12.2 0.2 0.092 12.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF416) Vpu PF00558.19 KKK44291.1 - 3.5 7.4 8.7 15 5.4 8.7 2.0 1 1 0 1 1 1 0 Vpu protein PIN PF01850.21 KKK44292.1 - 0.045 14.3 0.0 1.6 9.2 0.0 2.3 1 1 1 2 2 2 0 PIN domain FrhB_FdhB_C PF04432.13 KKK44293.1 - 4.6e-34 117.5 0.1 9.2e-34 116.5 0.1 1.5 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK44293.1 - 1.6e-15 57.0 0.0 3.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Fer4_9 PF13187.6 KKK44293.1 - 1e-05 25.6 7.9 1e-05 25.6 7.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK44293.1 - 1.2e-05 25.4 9.3 1.5e-05 25.0 7.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK44293.1 - 0.00015 21.8 19.8 0.0033 17.5 1.6 2.7 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK44293.1 - 0.00032 21.2 8.8 0.00032 21.2 8.8 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44293.1 - 0.0015 19.4 6.9 0.088 13.8 0.7 3.4 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK44293.1 - 0.0018 18.7 6.0 0.031 14.7 0.6 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK44293.1 - 0.006 16.6 2.0 0.006 16.6 2.0 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK44293.1 - 0.0087 16.1 1.2 0.0087 16.1 1.2 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_13 PF13370.6 KKK44293.1 - 0.011 16.2 0.5 0.011 16.2 0.5 3.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4 PF00037.27 KKK44293.1 - 0.017 14.9 2.5 0.017 14.9 2.5 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK44293.1 - 0.056 14.0 1.4 0.056 14.0 1.4 3.2 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK44293.1 - 0.067 14.0 5.6 0.77 10.6 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK44293.1 - 5.3 7.7 17.4 2.6 8.7 3.2 2.8 2 1 1 3 3 2 0 4Fe-4S dicluster domain DAP10 PF07213.11 KKK44294.1 - 0.13 12.2 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 DAP10 membrane protein CCG PF02754.16 KKK44295.1 - 1.1e-18 67.2 9.0 1.1e-09 38.4 0.2 3.3 3 0 0 3 3 3 2 Cysteine-rich domain Fer4_8 PF13183.6 KKK44295.1 - 1.7e-08 34.8 5.3 1.7e-08 34.8 5.3 2.5 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK44295.1 - 1.4e-06 28.3 6.4 1.4e-06 28.3 6.4 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK44295.1 - 1.6e-06 28.6 5.4 1.6e-06 28.6 5.4 3.0 3 1 1 4 4 4 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK44295.1 - 3.3e-06 27.1 17.6 2.7e-05 24.2 9.1 3.6 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK44295.1 - 1e-05 26.0 6.3 1e-05 26.0 6.3 3.0 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK44295.1 - 0.0022 18.1 9.4 0.0022 18.1 9.4 3.2 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK44295.1 - 0.048 14.5 0.7 0.048 14.5 0.7 4.0 4 1 1 5 5 5 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44295.1 - 0.072 12.9 18.1 0.067 13.0 2.7 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 KKK44295.1 - 0.18 12.8 15.6 0.35 11.8 0.1 3.7 4 1 0 4 4 3 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 KKK44295.1 - 0.47 10.7 8.9 1.4 9.1 1.1 2.9 1 1 2 3 3 3 0 4Fe-4S dicluster domain PDGF PF00341.17 KKK44295.1 - 0.68 10.3 9.5 1 9.7 0.1 3.5 3 0 0 3 3 3 0 PDGF/VEGF domain Fer4_2 PF12797.7 KKK44295.1 - 3.3 8.0 23.0 0.18 12.0 2.1 3.6 4 0 0 4 4 4 0 4Fe-4S binding domain Amidohydro_3 PF07969.11 KKK44298.1 - 5.2e-09 36.1 0.0 6.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KKK44298.1 - 6.7e-05 22.4 0.1 8.9e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family CoA_transf_3 PF02515.17 KKK44300.1 - 5.4e-107 358.1 0.0 6.1e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lipoprotein_1 PF00820.19 KKK44300.1 - 0.0066 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Borrelia lipoprotein PAS_3 PF08447.12 KKK44301.1 - 5.7e-28 97.0 0.0 1.8e-20 73.0 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 KKK44301.1 - 3.4e-22 78.6 0.0 2.5e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKK44301.1 - 1.7e-21 76.4 4.1 1.1e-13 51.3 0.1 2.8 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KKK44301.1 - 1.1e-17 64.3 0.0 6.9e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 KKK44301.1 - 3.5e-15 56.5 0.3 3.5e-15 56.5 0.3 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KKK44301.1 - 6.2e-11 42.1 0.0 8.9e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 KKK44301.1 - 1.7e-10 41.1 0.1 1.8e-09 37.7 0.0 2.5 3 0 0 3 3 3 1 PAS domain HATPase_c_5 PF14501.6 KKK44301.1 - 0.0003 20.6 3.4 0.0015 18.4 3.4 2.3 1 1 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KKK44301.1 - 0.051 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PAS_7 PF12860.7 KKK44301.1 - 0.061 13.5 0.5 13 6.0 0.0 3.0 2 2 0 2 2 2 0 PAS fold URO-D PF01208.17 KKK44302.1 - 5.8e-35 121.1 0.0 4.5e-34 118.1 0.0 2.0 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) B12-binding PF02310.19 KKK44303.1 - 8.6e-19 67.8 0.3 1.5e-18 67.0 0.3 1.4 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 KKK44303.1 - 1e-11 45.1 1.5 1.5e-11 44.6 0.4 1.8 2 0 0 2 2 2 1 B12 binding domain SepF PF04472.12 KKK44303.1 - 0.021 15.1 1.2 0.25 11.7 0.0 2.6 2 1 1 3 3 3 0 Cell division protein SepF Peripla_BP_6 PF13458.6 KKK44303.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein BLIP PF07467.11 KKK44304.1 - 0.084 13.5 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) CitMHS PF03600.16 KKK44304.1 - 0.23 10.6 5.1 0.37 10.0 5.1 1.2 1 0 0 1 1 1 0 Citrate transporter VWA_CoxE PF05762.14 KKK44306.1 - 3.1e-08 33.3 0.0 8.9e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Exo70 PF03081.15 KKK44306.1 - 3.3e-07 29.7 0.0 5.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit ACP_PD PF04336.12 KKK44306.1 - 0.027 14.9 0.8 0.12 12.8 0.8 2.2 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Prominin PF05478.11 KKK44306.1 - 0.032 12.2 1.7 0.051 11.5 1.7 1.3 1 0 0 1 1 1 0 Prominin DUF445 PF04286.12 KKK44306.1 - 0.036 13.9 1.0 0.059 13.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MCPsignal PF00015.21 KKK44308.1 - 4.5e-35 121.0 26.3 1.3e-33 116.2 8.5 2.9 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 KKK44308.1 - 8.6e-08 32.4 4.5 1.8e-07 31.4 0.0 3.4 5 0 0 5 5 3 1 HAMP domain EMP24_GP25L PF01105.24 KKK44308.1 - 0.0075 16.2 0.3 0.0075 16.2 0.3 3.3 2 1 0 2 2 2 1 emp24/gp25L/p24 family/GOLD DUF3739 PF12545.8 KKK44308.1 - 0.014 15.8 0.5 0.041 14.4 0.4 1.9 1 1 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein DUF2203 PF09969.9 KKK44308.1 - 0.016 15.9 2.4 1.2 9.8 0.2 3.3 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF3450 PF11932.8 KKK44308.1 - 0.018 14.3 3.5 1.3 8.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Sec34 PF04136.15 KKK44308.1 - 0.029 14.2 9.2 0.053 13.4 0.2 3.9 4 0 0 4 4 4 0 Sec34-like family Arfaptin PF06456.13 KKK44308.1 - 0.058 12.9 1.0 0.22 11.1 0.3 2.1 2 0 0 2 2 2 0 Arfaptin-like domain Med9 PF07544.13 KKK44308.1 - 0.079 13.1 2.1 0.49 10.5 0.5 3.0 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Sec8_exocyst PF04048.14 KKK44308.1 - 0.16 11.9 13.9 3.6 7.5 0.1 3.8 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 KKK44308.1 - 0.17 11.9 12.9 1.9 8.5 3.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 KKK44308.1 - 0.21 11.5 3.1 0.36 10.7 0.0 2.8 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein BAR PF03114.18 KKK44308.1 - 0.25 11.0 1.6 11 5.6 0.2 2.5 2 0 0 2 2 2 0 BAR domain T7SS_ESX_EspC PF10824.8 KKK44308.1 - 0.28 11.7 3.9 2.7 8.5 0.1 2.8 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm AI-2E_transport PF01594.16 KKK44308.1 - 0.32 10.1 5.3 0.33 10.0 3.8 1.9 2 0 0 2 2 2 0 AI-2E family transporter Tropomyosin PF00261.20 KKK44308.1 - 0.39 10.1 6.7 0.78 9.1 0.1 2.9 2 2 0 2 2 2 0 Tropomyosin HisKA PF00512.25 KKK44308.1 - 0.48 10.5 2.8 7.5 6.7 0.1 3.5 2 2 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Filament PF00038.21 KKK44308.1 - 0.5 9.9 7.5 2.6 7.6 0.3 2.6 2 1 0 3 3 3 0 Intermediate filament protein Golgin_A5 PF09787.9 KKK44308.1 - 0.66 9.4 6.9 0.5 9.8 0.2 2.9 3 0 0 3 3 3 0 Golgin subfamily A member 5 Atg14 PF10186.9 KKK44308.1 - 1.2 8.1 6.1 5.1 6.1 0.2 2.3 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG2 PF06148.11 KKK44308.1 - 1.3 9.1 7.0 9.9 6.3 0.7 3.7 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Stevor PF17410.2 KKK44308.1 - 2.4 7.6 9.2 0.11 12.0 0.8 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Fzo_mitofusin PF04799.13 KKK44308.1 - 2.8 7.5 8.5 2.4 7.7 0.1 3.3 3 1 1 4 4 4 0 fzo-like conserved region CENP-F_leu_zip PF10473.9 KKK44308.1 - 4.2 7.4 8.9 5.1 7.1 1.3 3.3 3 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KKK44308.1 - 4.8 7.6 8.4 18 5.7 0.6 2.7 2 1 1 3 3 2 0 Fez1 I_LWEQ PF01608.17 KKK44308.1 - 6.1 7.1 9.6 12 6.1 5.1 2.6 1 1 2 3 3 3 0 I/LWEQ domain DUF948 PF06103.11 KKK44308.1 - 7.2 6.9 21.1 1.9 8.8 0.2 4.8 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4665 PF15679.5 KKK44308.1 - 8.6 7.1 6.7 25 5.6 0.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4665) 4HB_MCP_1 PF12729.7 KKK44309.1 - 8e-08 32.0 0.1 8.5e-08 31.9 0.1 1.0 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction Ribosomal_S17 PF00366.20 KKK44313.1 - 9.1e-20 70.5 1.0 9.1e-20 70.5 1.0 1.3 2 0 0 2 2 2 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 KKK44313.1 - 0.0058 17.0 1.4 0.0064 16.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal PRF PF06875.11 KKK44313.1 - 0.024 14.1 0.1 0.034 13.6 0.1 1.1 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF UPF0086 PF01868.16 KKK44314.1 - 1.1e-06 28.4 0.2 1.6e-06 27.9 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Ribosomal_L29 PF00831.23 KKK44315.1 - 5.6e-13 48.6 0.8 7.1e-13 48.3 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein Ribosomal_S3_C PF00189.20 KKK44316.1 - 5.5e-17 62.1 4.1 6.3e-17 61.9 1.9 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KKK44316.1 - 6.5e-15 54.7 0.1 1.4e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 KKK44316.1 - 0.012 15.4 1.1 0.023 14.5 0.4 1.9 2 0 0 2 2 2 0 KH domain Ribosomal_L6e PF01159.19 KKK44316.1 - 0.16 12.6 2.9 0.72 10.4 1.1 2.3 1 1 1 2 2 2 0 Ribosomal protein L6e Adenylsucc_synt PF00709.21 KKK44320.1 - 1.7e-122 409.4 0.0 2.1e-122 409.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Corona_RPol_N PF06478.13 KKK44320.1 - 0.023 13.7 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus DUF2284 PF10050.9 KKK44321.1 - 1.8e-26 92.9 1.0 2.5e-26 92.4 1.0 1.2 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) PhoU_div PF01865.16 KKK44322.1 - 2.4e-14 53.2 10.5 2.8e-14 52.9 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 HEAT_UF PF18817.1 KKK44322.1 - 0.2 11.9 2.2 16 5.8 0.1 2.8 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 PHO4 PF01384.20 KKK44323.1 - 1.8e-54 185.0 29.0 3.4e-54 184.1 29.0 1.4 1 1 0 1 1 1 1 Phosphate transporter family DapB_N PF01113.20 KKK44324.1 - 6.5e-08 32.7 0.1 3.2e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 KKK44324.1 - 1.6e-05 25.5 1.3 4.2e-05 24.1 0.0 2.3 3 0 0 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.22 KKK44324.1 - 3.8e-05 24.5 0.0 6.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.19 KKK44324.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PglD_N PF17836.1 KKK44324.1 - 0.035 14.7 0.2 0.13 12.9 0.1 2.1 2 0 0 2 2 2 0 PglD N-terminal domain NAD_binding_3 PF03447.16 KKK44324.1 - 0.067 13.8 0.0 0.2 12.3 0.0 1.8 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Aminotran_3 PF00202.21 KKK44325.1 - 3e-41 141.4 0.0 5.5e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III Arc_PepC PF06819.11 KKK44325.1 - 0.074 13.2 0.7 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain DUF3800 PF12686.7 KKK44325.1 - 0.079 13.6 1.4 0.17 12.5 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF4870 PF09685.10 KKK44326.1 - 0.014 15.5 3.6 0.02 15.0 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) RseC_MucC PF04246.12 KKK44326.1 - 0.67 9.9 2.4 1 9.3 2.4 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC VWA PF00092.28 KKK44327.1 - 0.00059 20.1 0.2 0.00096 19.4 0.2 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-ribbon_3 PF13248.6 KKK44327.1 - 7.3 6.1 18.4 8.3 6.0 4.1 4.1 3 1 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK44328.1 - 0.00027 20.6 4.2 0.00027 20.6 4.2 3.0 4 0 0 4 4 4 1 zinc-ribbon domain DUF3387 PF11867.8 KKK44328.1 - 0.0029 17.1 0.1 0.0058 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) DZR PF12773.7 KKK44328.1 - 0.0071 16.4 1.4 0.0071 16.4 1.4 3.1 2 1 0 2 2 2 1 Double zinc ribbon Cript PF10235.9 KKK44328.1 - 0.0072 16.9 3.3 0.0072 16.9 3.3 2.6 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT Ribosomal_L37e PF01907.19 KKK44328.1 - 0.011 15.9 0.5 0.011 15.9 0.5 1.9 2 0 0 2 2 2 0 Ribosomal protein L37e zinc_ribbon_5 PF13719.6 KKK44328.1 - 0.41 10.4 0.0 0.41 10.4 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Sigma70_r1_2 PF00140.20 KKK44329.1 - 0.016 15.2 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 MKT1_N PF12247.8 KKK44329.1 - 0.14 12.6 0.5 0.63 10.4 0.5 2.1 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication eIF-5_eIF-2B PF01873.17 KKK44329.1 - 3.7 7.4 8.3 0.39 10.6 0.8 2.9 3 0 0 3 3 3 0 Domain found in IF2B/IF5 CDP-OH_P_transf PF01066.21 KKK44330.1 - 2.4e-10 41.0 1.0 2.4e-10 41.0 1.0 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3262 PF11660.8 KKK44330.1 - 0.26 11.7 0.3 0.26 11.7 0.3 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3262) LOR PF04525.12 KKK44331.1 - 1.2e-07 31.5 0.0 2.5e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 LURP-one-related zinc_ribbon_2 PF13240.6 KKK44331.1 - 4.7e-07 29.3 4.2 7.6e-07 28.6 4.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK44331.1 - 7.1e-05 22.7 1.3 0.00011 22.2 1.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon Scramblase PF03803.15 KKK44331.1 - 0.00015 21.1 0.1 0.00026 20.4 0.1 1.3 1 0 0 1 1 1 1 Scramblase NOB1_Zn_bind PF08772.11 KKK44331.1 - 0.012 15.7 3.2 0.024 14.8 3.2 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF4539 PF15072.6 KKK44331.1 - 0.015 15.4 0.1 5.5 7.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4539) zf-ribbon_3 PF13248.6 KKK44331.1 - 0.017 14.5 4.3 0.034 13.6 4.3 1.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF2116 PF09889.9 KKK44331.1 - 0.019 15.0 2.5 0.04 13.9 2.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Nudix_N_2 PF14803.6 KKK44331.1 - 0.021 14.7 1.9 0.43 10.5 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal DUF3659 PF12396.8 KKK44331.1 - 0.055 13.4 0.1 1 9.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3659) zf_UBZ PF18439.1 KKK44331.1 - 0.07 12.7 2.5 0.74 9.5 0.5 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 KKK44331.1 - 0.34 11.7 3.8 0.54 11.0 3.8 1.3 1 0 0 1 1 1 0 zinc-ribbon family zf-NADH-PPase PF09297.11 KKK44331.1 - 0.61 9.8 3.5 9.2 6.0 0.2 2.3 1 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain YhfH PF14149.6 KKK44331.1 - 2.6 8.1 6.2 14 5.7 1.0 2.3 1 1 1 2 2 2 0 YhfH-like protein Gelsolin PF00626.22 KKK44332.1 - 0.003 17.4 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat BcrAD_BadFG PF01869.20 KKK44334.1 - 1.3e-41 142.9 1.0 1.6e-41 142.6 1.0 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 KKK44334.1 - 0.065 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain KI67R PF08065.12 KKK44335.1 - 0.14 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 KI67R (NUC007) repeat MULE PF10551.9 KKK44337.1 - 0.013 15.9 0.1 0.043 14.2 0.0 1.9 2 0 0 2 2 2 0 MULE transposase domain HTH_11 PF08279.12 KKK44337.1 - 0.015 15.2 0.0 0.062 13.3 0.0 2.1 1 1 0 1 1 1 0 HTH domain DUF2576 PF10845.8 KKK44337.1 - 0.091 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Mating_N PF12731.7 KKK44337.1 - 0.12 12.4 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 Myb_DNA-bind_3 PF12776.7 KKK44337.1 - 0.2 12.7 2.2 4.4 8.3 0.1 2.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Seryl_tRNA_N PF02403.22 KKK44337.1 - 1.3 9.3 6.1 4.6 7.5 1.2 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MutS_III PF05192.18 KKK44337.1 - 5.7 7.1 5.7 19 5.4 5.6 2.2 1 1 0 1 1 1 0 MutS domain III zf-CDGSH PF09360.10 KKK44338.1 - 5.3e-37 125.8 4.3 4.4e-18 65.2 0.1 2.7 3 0 0 3 3 3 2 Iron-binding zinc finger CDGSH type Fer4_19 PF06902.11 KKK44338.1 - 2.1e-06 27.7 0.1 6e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Chisel PF15355.6 KKK44338.1 - 0.096 12.9 0.0 3.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel PTSIIA_gutA PF03829.13 KKK44338.1 - 0.15 11.9 0.0 0.91 9.4 0.0 2.2 2 1 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component PadR PF03551.14 KKK44339.1 - 0.00065 19.6 0.0 0.00088 19.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family DUF4364 PF14277.6 KKK44339.1 - 0.0031 17.3 0.1 0.0032 17.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_45 PF14947.6 KKK44339.1 - 0.0069 16.4 0.1 0.0089 16.0 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix CTP_transf_1 PF01148.20 KKK44341.1 - 0.00025 20.9 12.4 0.00039 20.3 12.4 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family Gag_spuma PF03276.14 KKK44341.1 - 0.25 9.7 0.2 0.33 9.3 0.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PRA1 PF03208.19 KKK44341.1 - 0.7 9.5 9.4 1.7 8.2 4.6 2.2 2 0 0 2 2 2 0 PRA1 family protein DUF4395 PF14340.6 KKK44341.1 - 2.1 8.7 8.6 0.68 10.3 3.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) Hydrolase_6 PF13344.6 KKK44342.1 - 6.4e-27 93.6 0.1 1.1e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK44342.1 - 2.6e-13 49.8 0.0 5.9e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK44342.1 - 1.9e-11 44.7 0.0 4e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK44342.1 - 1.3e-09 38.4 7.8 4.3e-06 26.9 0.0 3.3 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KKK44342.1 - 0.0017 18.0 0.2 0.003 17.2 0.2 1.4 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.12 KKK44342.1 - 0.005 16.6 0.2 0.11 12.2 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PBP_like PF12727.7 KKK44342.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain PGP_phosphatase PF09419.10 KKK44342.1 - 0.1 12.2 2.1 0.25 10.9 0.0 2.3 2 1 1 3 3 3 0 Mitochondrial PGP phosphatase Ras PF00071.22 KKK44343.1 - 6.7e-45 152.6 0.0 7.7e-45 152.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44343.1 - 5.6e-25 87.9 0.0 8.1e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44343.1 - 8.1e-10 38.4 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK44343.1 - 0.0014 18.7 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK44343.1 - 0.0045 16.9 0.1 0.037 13.9 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KKK44343.1 - 0.024 14.4 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KKK44343.1 - 0.037 14.3 0.2 0.11 12.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 KKK44343.1 - 0.065 12.7 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK44343.1 - 0.076 12.4 0.1 0.11 11.8 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KKK44343.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KKK44343.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 KKK44343.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KKK44343.1 - 0.21 12.1 0.1 0.49 10.9 0.0 1.6 2 0 0 2 2 2 0 ABC transporter DUF362 PF04015.12 KKK44344.1 - 9e-41 140.3 0.0 1.2e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF362) Fer4_21 PF14697.6 KKK44344.1 - 0.00015 21.8 12.1 0.00045 20.3 12.1 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK44344.1 - 0.00023 21.7 14.9 0.00071 20.1 15.1 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44344.1 - 0.00024 22.0 13.6 0.0015 19.4 1.6 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK44344.1 - 0.00042 20.4 15.0 0.0012 18.9 15.2 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44344.1 - 0.0005 19.8 15.1 0.0013 18.4 3.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK44344.1 - 0.00064 19.7 18.0 0.011 15.8 5.1 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK44344.1 - 0.0071 16.9 9.0 0.068 13.7 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK44344.1 - 0.0075 16.4 14.0 0.018 15.2 14.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK44344.1 - 0.037 14.2 6.6 0.083 13.1 6.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK44344.1 - 0.81 10.5 9.6 0.45 11.3 1.4 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_2 PF12797.7 KKK44344.1 - 1 9.6 15.6 0.17 12.0 3.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Peptidase_M20 PF01546.28 KKK44345.1 - 5e-16 59.0 0.0 7e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK44345.1 - 9.5e-11 41.6 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain UDPG_MGDP_dh PF00984.19 KKK44345.1 - 0.085 13.1 0.1 0.41 10.9 0.0 2.2 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain Robl_LC7 PF03259.17 KKK44346.1 - 1.1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain MAPKK1_Int PF08923.10 KKK44346.1 - 0.018 14.8 0.4 0.022 14.6 0.4 1.1 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting HEAT_2 PF13646.6 KKK44347.1 - 3.6e-71 235.6 0.2 2.2e-15 56.8 0.0 7.8 3 1 4 8 8 8 8 HEAT repeats HEAT PF02985.22 KKK44347.1 - 8.5e-35 115.8 0.0 0.0033 17.6 0.0 12.2 12 0 0 12 12 12 8 HEAT repeat HEAT_PBS PF03130.16 KKK44347.1 - 1.4e-27 93.5 0.0 0.00065 20.1 0.0 10.4 10 1 0 10 10 10 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KKK44347.1 - 2.8e-14 53.2 0.0 7 7.3 0.0 10.5 11 1 1 12 12 11 1 HEAT-like repeat Cnd1 PF12717.7 KKK44347.1 - 1.2e-10 41.7 12.7 0.00083 19.4 1.3 6.8 2 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KKK44347.1 - 9.6e-09 35.0 0.0 2 8.6 0.0 7.8 9 1 1 10 10 9 2 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 KKK44347.1 - 4.3e-07 30.3 2.3 1.2 9.6 0.0 5.5 5 2 1 6 6 5 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Aconitase_B_N PF11791.8 KKK44347.1 - 2e-06 27.9 5.5 0.056 13.5 0.0 6.6 4 2 5 9 9 9 1 Aconitate B N-terminal domain Vac14_Fab1_bd PF12755.7 KKK44347.1 - 0.00069 20.2 0.5 18 6.0 0.0 5.6 2 2 4 6 6 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KKK44347.1 - 0.0033 17.0 6.5 0.24 11.0 0.2 5.2 2 1 2 5 5 5 1 CLASP N terminal RICTOR_M PF14666.6 KKK44347.1 - 0.0047 16.7 2.0 2.7 7.8 0.0 4.6 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain Cohesin_HEAT PF12765.7 KKK44347.1 - 0.025 14.9 0.6 49 4.4 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion TPR_20 PF14561.6 KKK44347.1 - 0.055 13.8 7.3 11 6.5 0.2 5.1 5 1 1 6 6 5 0 Tetratricopeptide repeat AHD PF17793.1 KKK44347.1 - 0.14 12.0 0.9 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 ANC1 homology domain (AHD) CTV_P13 PF06922.11 KKK44349.1 - 0.061 13.4 0.0 0.061 13.4 0.0 1.0 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein LAGLIDADG_3 PF14528.6 KKK44350.1 - 0.00012 22.4 1.0 0.2 12.0 0.0 3.5 3 0 0 3 3 3 2 LAGLIDADG-like domain AMP-binding PF00501.28 KKK44351.1 - 1.7e-92 310.3 0.0 2e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK44351.1 - 5.9e-25 88.1 0.1 1.2e-24 87.1 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KKK44351.1 - 2.5e-22 78.5 5.9 2.7e-22 78.4 3.8 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AcetylCoA_hyd_C PF13336.6 KKK44352.1 - 7.9e-58 194.8 0.0 1.5e-57 193.9 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KKK44352.1 - 7.6e-24 84.8 0.0 1.3e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Acetyltransf_1 PF00583.25 KKK44352.1 - 3.5e-09 36.9 0.1 8.7e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KKK44352.1 - 7.2e-05 23.5 0.0 0.00012 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK44352.1 - 0.00034 20.5 0.1 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK44352.1 - 0.00043 20.7 0.1 0.0012 19.2 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK44352.1 - 0.00059 20.0 0.1 0.001 19.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DeoRC PF00455.22 KKK44352.1 - 0.04 13.8 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Acetyltransf_CG PF14542.6 KKK44352.1 - 0.043 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase URO-D PF01208.17 KKK44355.1 - 0.00029 20.1 0.0 0.00029 20.1 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) SNARE_assoc PF09335.11 KKK44356.1 - 7e-12 45.9 5.0 9.7e-11 42.2 1.8 2.1 2 0 0 2 2 2 2 SNARE associated Golgi protein DUF5371 PF17341.2 KKK44357.1 - 0.12 12.6 0.3 0.29 11.4 0.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5371) AP_endonuc_2 PF01261.24 KKK44358.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF5618 PF18498.1 KKK44358.1 - 0.11 12.6 1.3 9.5 6.4 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5618) CDP-OH_P_transf PF01066.21 KKK44359.1 - 9.3e-11 42.3 0.8 9.3e-11 42.3 0.8 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Amidohydro_3 PF07969.11 KKK44362.1 - 4.7e-13 49.4 0.0 6.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KKK44362.1 - 7.4e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family DUF108 PF01958.18 KKK44362.1 - 0.025 14.9 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF108 Retrotran_gag_3 PF14244.6 KKK44362.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type CoA_transf_3 PF02515.17 KKK44363.1 - 6.8e-110 367.6 0.0 7.7e-110 367.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lipoprotein_1 PF00820.19 KKK44363.1 - 0.0099 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Borrelia lipoprotein PAS PF00989.25 KKK44364.1 - 4e-23 81.6 0.0 1.1e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KKK44364.1 - 4.2e-20 71.8 0.1 7.2e-13 48.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKK44364.1 - 2.6e-17 62.9 4.8 3e-08 33.8 0.1 2.8 3 0 0 3 3 3 2 PAS domain HATPase_c PF02518.26 KKK44364.1 - 7.3e-16 58.7 0.3 1.8e-15 57.4 0.2 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 KKK44364.1 - 2.3e-13 50.3 0.0 2.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KKK44364.1 - 5.2e-09 35.9 0.0 0.0002 21.3 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 KKK44364.1 - 3.2e-07 30.5 0.3 4.3e-06 26.8 0.0 2.5 3 0 0 3 3 3 1 PAS domain HATPase_c_5 PF14501.6 KKK44364.1 - 0.0033 17.3 5.2 0.0033 17.3 5.2 2.9 2 1 0 2 2 2 1 GHKL domain Ntox44 PF15607.6 KKK44364.1 - 0.032 14.5 1.3 0.081 13.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial toxin 44 PAS_7 PF12860.7 KKK44364.1 - 0.061 13.5 0.2 6.1 7.0 0.0 3.0 3 1 0 3 3 3 0 PAS fold URO-D PF01208.17 KKK44365.1 - 7e-33 114.2 0.0 6e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) B12-binding PF02310.19 KKK44366.1 - 4.7e-19 68.6 0.5 8.1e-19 67.8 0.5 1.4 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 KKK44366.1 - 1.5e-11 44.6 0.4 1.5e-11 44.6 0.4 2.1 2 1 0 2 2 2 1 B12 binding domain Peripla_BP_6 PF13458.6 KKK44366.1 - 0.086 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein SepF PF04472.12 KKK44366.1 - 0.13 12.6 1.7 1.2 9.5 0.1 2.7 2 1 1 3 3 3 0 Cell division protein SepF CheR PF01739.18 KKK44369.1 - 8.7e-42 142.8 0.4 8.9e-41 139.5 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 KKK44369.1 - 6.5e-12 45.0 1.6 2.3e-11 43.2 1.6 2.0 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 KKK44369.1 - 3.8e-06 27.6 0.1 0.011 16.5 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK44369.1 - 7.2e-06 25.9 0.0 0.00097 19.0 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK44369.1 - 1.2e-05 26.0 0.0 0.001 19.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK44369.1 - 0.0035 17.9 0.0 0.032 14.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain HAD_2 PF13419.6 KKK44370.1 - 2e-26 93.1 0.8 3.6e-26 92.3 0.8 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK44370.1 - 1.2e-11 45.4 0.0 5.3e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK44370.1 - 8.2e-11 41.8 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Put_Phosphatase PF06888.12 KKK44370.1 - 0.00016 21.2 0.2 0.047 13.1 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase HAD PF12710.7 KKK44370.1 - 0.023 15.1 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SPOB_ab PF14682.6 KKK44370.1 - 0.11 12.6 1.2 0.19 11.8 0.3 1.8 2 1 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal Hydrolase_3 PF08282.12 KKK44370.1 - 0.61 9.8 3.8 0.4 10.4 0.4 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fer4_9 PF13187.6 KKK44372.1 - 0.0016 18.6 6.6 0.017 15.3 3.1 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK44372.1 - 0.0051 17.4 2.8 0.17 12.5 1.4 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK44372.1 - 0.0095 16.0 5.3 0.068 13.3 2.0 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK44372.1 - 0.034 14.2 3.6 0.034 14.2 3.6 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 KKK44372.1 - 0.24 12.4 5.6 1.7 9.6 2.7 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK44372.1 - 0.3 11.6 5.6 2.8 8.5 2.8 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44372.1 - 0.5 10.3 12.2 0.05 13.4 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 KKK44372.1 - 7.1 6.9 11.9 1.1 9.5 3.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DZR PF12773.7 KKK44373.1 - 0.026 14.6 0.0 0.055 13.5 0.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-FPG_IleRS PF06827.14 KKK44373.1 - 0.029 14.2 5.6 0.79 9.6 0.9 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 KKK44373.1 - 0.053 13.1 2.2 1.3 8.7 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger RPA_interact_C PF14768.6 KKK44374.1 - 0.003 18.1 0.1 0.003 18.1 0.1 1.2 1 0 0 1 1 1 1 Replication protein A interacting C-terminal zf-RRPl_C4 PF17026.5 KKK44374.1 - 0.017 15.2 0.3 0.02 15.0 0.3 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type TackOD1 PF18551.1 KKK44374.1 - 0.018 14.7 1.1 0.028 14.1 1.1 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 KKK44374.1 - 0.028 14.4 0.5 0.036 14.0 0.5 1.3 1 0 0 1 1 1 0 zinc-ribbons NCD3G PF07562.14 KKK44374.1 - 0.048 13.6 2.2 0.07 13.1 2.2 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DNA_RNApol_7kD PF03604.13 KKK44374.1 - 0.06 13.0 2.8 0.092 12.4 2.8 1.2 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 KKK44374.1 - 2.3 8.4 6.5 2.6 8.3 0.7 2.5 2 1 1 3 3 3 0 Zinc ribbon domain DUF2975 PF11188.8 KKK44376.1 - 1.2 9.0 14.1 0.073 13.0 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) FliP PF00813.20 KKK44376.1 - 9.9 6.0 10.1 0.12 12.2 2.4 1.7 2 1 0 2 2 2 0 FliP family DUF681 PF05080.12 KKK44377.1 - 0.034 14.8 0.0 0.035 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF681) LRR_4 PF12799.7 KKK44378.1 - 0.00021 21.6 0.7 0.00021 21.6 0.7 1.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK44378.1 - 0.0013 18.5 1.7 0.0021 17.8 1.0 1.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 KKK44378.1 - 0.058 14.0 0.1 0.24 12.1 0.1 2.1 1 1 0 1 1 1 0 Leucine Rich Repeat Acyltransferase PF01553.21 KKK44379.1 - 6.5e-48 161.8 0.0 5.2e-25 87.6 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase DUF2229 PF09989.9 KKK44380.1 - 3.9e-46 157.4 0.0 5.3e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 CoA enzyme activase uncharacterised domain (DUF2229) HGD-D PF06050.13 KKK44380.1 - 2.1e-05 24.5 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component Toxin_trans PF07952.12 KKK44380.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain BAR PF03114.18 KKK44380.1 - 0.083 12.5 0.3 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 BAR domain DUF4795 PF16043.5 KKK44381.1 - 0.07 12.7 8.2 0.088 12.4 8.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KxDL PF10241.9 KKK44381.1 - 0.24 11.7 10.4 0.081 13.2 3.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein MRP-L28 PF09812.9 KKK44381.1 - 4.4 7.4 8.6 0.21 11.7 1.4 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L28 Metallophos_2 PF12850.7 KKK44382.1 - 2.6e-19 70.0 0.0 3.3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KKK44382.1 - 8.2e-09 36.2 1.8 1.2e-07 32.5 1.8 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ly49 PF08391.10 KKK44382.1 - 0.085 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Lipase_3 PF01764.25 KKK44382.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Zn_Tnp_IS1595 PF12760.7 KKK44383.1 - 0.0095 15.9 0.9 0.02 14.8 0.9 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 KKK44383.1 - 0.013 15.4 0.4 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-CCHC_6 PF15288.6 KKK44383.1 - 0.019 14.8 0.1 0.019 14.8 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF2977 PF11192.8 KKK44383.1 - 0.04 14.0 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) Zn-ribbon_8 PF09723.10 KKK44383.1 - 0.06 13.5 3.0 2.4 8.3 1.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Imm31 PF15591.6 KKK44383.1 - 0.15 11.9 0.2 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 31 zf-ribbon_3 PF13248.6 KKK44383.1 - 0.24 10.9 1.5 4.8 6.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KKK44383.1 - 0.26 11.2 4.0 0.88 9.5 3.5 2.0 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-HIT PF04438.16 KKK44383.1 - 0.29 11.1 4.4 1.5 8.8 1.1 2.4 2 0 0 2 2 2 0 HIT zinc finger zf-IS66 PF13005.7 KKK44383.1 - 0.35 11.3 11.3 8.9 6.8 6.4 3.3 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-C2HE PF16278.5 KKK44383.1 - 0.5 10.9 4.5 0.81 10.2 0.7 2.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_2 PF13240.6 KKK44383.1 - 1 9.2 4.2 14 5.6 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_M20 PF01546.28 KKK44384.1 - 3.2e-13 49.9 0.0 4.3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KKK44384.1 - 2e-07 30.3 0.0 0.0084 15.2 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase M20_dimer PF07687.14 KKK44384.1 - 2.2e-07 30.7 0.0 5.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK44384.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M28 Abhydrolase_1 PF00561.20 KKK44386.1 - 1.1e-19 71.1 0.0 3.9e-19 69.3 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK44386.1 - 6.3e-12 45.3 0.0 1.2e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK44386.1 - 1.8e-09 38.5 0.0 2.2e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KKK44386.1 - 8.3e-05 22.1 0.0 0.00056 19.5 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family DUF676 PF05057.14 KKK44386.1 - 0.0063 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) RNA_pol_I_TF PF04090.12 KKK44386.1 - 0.018 14.5 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor DUF915 PF06028.11 KKK44386.1 - 0.021 14.2 0.4 0.089 12.1 0.2 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) SRP54 PF00448.22 KKK44386.1 - 0.054 13.1 0.2 0.39 10.3 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Thioesterase PF00975.20 KKK44386.1 - 0.057 13.5 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain Palm_thioest PF02089.15 KKK44386.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Ndr PF03096.14 KKK44386.1 - 0.11 11.1 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Ndr family HAD_2 PF13419.6 KKK44387.1 - 3.1e-23 82.8 0.7 5.2e-23 82.0 0.7 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK44387.1 - 2.5e-14 54.1 0.0 2e-13 51.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK44387.1 - 3e-05 24.0 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KKK44387.1 - 0.016 15.3 0.0 0.16 12.1 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Radical_SAM PF04055.21 KKK44389.1 - 2.4e-08 34.5 0.1 6.4e-08 33.1 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Peptidase_S74 PF13884.6 KKK44389.1 - 0.078 13.3 0.2 0.87 9.9 0.2 2.5 1 1 0 1 1 1 0 Chaperone of endosialidase Rep_Org_C PF06926.11 KKK44389.1 - 0.1 13.0 0.2 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus tRNA-synt_2d PF01409.20 KKK44392.1 - 2.2e-90 302.5 0.0 2.9e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 KKK44392.1 - 2.5e-07 30.1 0.1 0.00073 18.7 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 KKK44392.1 - 1.3e-05 24.8 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 KKK44392.1 - 0.0016 18.5 0.1 0.0052 16.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_synthFbeta PF17759.1 KKK44393.1 - 5.4e-46 156.7 0.0 7.6e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 KKK44393.1 - 4e-16 59.1 0.4 2.7e-12 46.8 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 KKK44393.1 - 1.2e-11 44.7 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 KKK44393.1 - 1.2e-06 28.6 0.1 4.4e-05 23.6 0.0 2.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain tRNA-synt_2d PF01409.20 KKK44393.1 - 0.00027 20.5 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PDT PF00800.18 KKK44394.1 - 6.5e-60 202.1 0.0 9.2e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 KKK44394.1 - 1.5e-22 79.8 2.6 4.5e-22 78.2 2.6 1.9 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 KKK44394.1 - 1.4e-05 24.7 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain FlaC_arch PF05377.11 KKK44394.1 - 6.4 7.3 7.5 10 6.6 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RNase_PH PF01138.21 KKK44395.1 - 3.1e-22 79.5 0.0 5.7e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK44395.1 - 1.1e-09 38.2 0.8 1.8e-09 37.5 0.8 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Sulfatase PF00884.23 KKK44396.1 - 1.4e-16 60.8 0.1 2e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK44396.1 - 0.0019 17.9 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 KKK44396.1 - 0.021 15.6 0.1 0.036 14.8 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.18 KKK44396.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily PNP_UDP_1 PF01048.20 KKK44400.1 - 2.3e-19 69.6 0.0 2.8e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Radical_SAM PF04055.21 KKK44401.1 - 1.4e-14 54.8 0.1 1.4e-08 35.3 0.0 2.4 1 1 1 2 2 2 2 Radical SAM superfamily Fer4_14 PF13394.6 KKK44401.1 - 0.038 14.1 0.1 15 5.7 0.0 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK44401.1 - 0.046 14.0 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain HTH_45 PF14947.6 KKK44401.1 - 1.1 9.3 8.5 0.55 10.3 5.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix Hydrolase PF00702.26 KKK44402.1 - 2e-07 31.5 0.0 2.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK44402.1 - 5.3e-06 26.3 1.5 1.7e-05 24.7 0.2 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK44402.1 - 6e-06 26.8 0.0 1.2e-05 25.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKK44402.1 - 0.00079 18.9 1.0 0.0035 16.8 1.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase NT5C PF06941.12 KKK44402.1 - 0.003 17.4 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) MMR_HSR1 PF01926.23 KKK44403.1 - 5.8e-12 45.7 0.1 8.3e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK44403.1 - 7.1e-08 32.1 0.4 7.2e-06 25.6 0.2 2.7 1 1 1 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK44403.1 - 3.8e-05 23.3 0.6 0.0006 19.4 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK44403.1 - 0.00016 21.6 1.3 0.1 12.5 0.1 2.6 2 2 0 2 2 2 2 RsgA GTPase Ras PF00071.22 KKK44403.1 - 0.0062 16.1 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KKK44403.1 - 0.016 15.4 0.1 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKK44403.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KKK44403.1 - 0.032 14.7 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 KKK44403.1 - 0.045 13.2 0.7 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 KKK44403.1 - 0.047 14.0 0.0 0.16 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain MBA1 PF07961.11 KKK44403.1 - 0.074 12.1 3.2 0.15 11.1 3.2 1.4 1 0 0 1 1 1 0 MBA1-like protein AAA_29 PF13555.6 KKK44403.1 - 0.18 11.6 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain zinc_ribbon_15 PF17032.5 KKK44404.1 - 0.00056 20.6 1.5 0.00059 20.5 1.5 1.2 1 0 0 1 1 1 1 zinc-ribbon family zinc_ribbon_2 PF13240.6 KKK44404.1 - 0.0038 16.9 3.8 0.0038 16.9 3.8 2.1 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 KKK44404.1 - 0.0055 16.7 2.3 0.0098 15.9 2.5 1.4 1 1 0 1 1 1 1 Double zinc ribbon Auto_anti-p27 PF06677.12 KKK44404.1 - 0.0075 16.4 1.3 0.32 11.2 0.1 2.5 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Nudix_N_2 PF14803.6 KKK44404.1 - 0.016 15.2 1.5 1.8 8.5 0.8 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 KKK44404.1 - 0.038 13.4 2.9 0.064 12.7 2.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain YhfH PF14149.6 KKK44404.1 - 0.19 11.7 4.6 8.4 6.5 4.0 2.3 1 1 1 2 2 2 0 YhfH-like protein DUF2321 PF10083.9 KKK44404.1 - 0.23 11.1 2.8 0.36 10.4 0.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2HCIx2C PF10782.9 KKK44404.1 - 0.24 11.4 4.9 4.6 7.2 0.3 2.2 1 1 1 2 2 2 0 Zinc-finger Vps36-NZF-N PF16988.5 KKK44404.1 - 0.29 10.5 4.1 7.2 6.1 0.8 2.3 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain YdiH PF15930.5 KKK44405.1 - 0.098 12.8 0.9 0.37 11.0 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function Cytochrom_B562 PF07361.11 KKK44405.1 - 0.37 11.5 5.3 0.9 10.2 3.9 2.1 1 1 1 2 2 2 0 Cytochrome b562 SpecificRecomb PF10136.9 KKK44405.1 - 0.56 8.4 3.0 0.65 8.2 3.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase N_formyltrans_C PF18216.1 KKK44405.1 - 0.76 9.5 8.4 0.24 11.1 1.5 2.7 3 0 0 3 3 3 0 N-formyltransferase dimerization C-terminal domain Golgin_A5 PF09787.9 KKK44405.1 - 5.3 6.4 22.2 9.3 5.6 6.5 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Iron_permease PF04120.12 KKK44405.1 - 8.6 6.2 7.4 2.8 7.7 1.2 2.4 1 1 1 2 2 2 0 Low affinity iron permease Ras PF00071.22 KKK44406.1 - 1.9e-26 92.6 0.0 2.2e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44406.1 - 9.7e-16 58.1 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44406.1 - 3.7e-06 26.5 0.0 4.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK44406.1 - 0.021 14.4 0.0 0.029 13.9 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain GTP_EFTU PF00009.27 KKK44407.1 - 1.5e-47 161.6 0.0 2.3e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KKK44407.1 - 1.7e-20 72.8 0.0 6.3e-20 71.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KKK44407.1 - 3.8e-13 49.3 0.0 7.8e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KKK44407.1 - 3e-09 36.7 0.0 8.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KKK44407.1 - 0.0072 16.7 0.0 0.027 14.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 HATPase_c PF02518.26 KKK44408.1 - 1.1e-16 61.4 0.0 1.8e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NnrS PF05940.12 KKK44408.1 - 0.012 15.0 2.8 0.012 15.0 2.8 1.8 1 1 1 2 2 2 0 NnrS protein HATPase_c_5 PF14501.6 KKK44408.1 - 0.024 14.5 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 GHKL domain ABC2_membrane PF01061.24 KKK44408.1 - 0.26 10.7 17.3 0.5 9.7 17.3 1.4 1 1 0 1 1 1 0 ABC-2 type transporter RSN1_TM PF13967.6 KKK44408.1 - 0.29 10.9 8.7 2.5 7.8 8.6 2.3 1 1 0 1 1 1 0 Late exocytosis, associated with Golgi transport tRNA_NucTransf2 PF09249.11 KKK44409.1 - 7.1e-22 77.8 0.4 1.7e-21 76.5 0.1 1.8 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain GTP_EFTU_D4 PF14578.6 KKK44410.1 - 5.6e-26 90.3 0.1 2.1e-25 88.4 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 4 IF-2 PF11987.8 KKK44410.1 - 9.2e-21 73.9 3.8 9.6e-21 73.9 1.9 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KKK44410.1 - 6.8e-06 26.4 1.9 2.1e-05 24.8 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Sec23_helical PF04815.15 KKK44410.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Acetyltransf_18 PF18014.1 KKK44414.1 - 4.2e-19 68.6 0.1 9.8e-19 67.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK44414.1 - 3.8e-11 43.0 0.0 6.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK44414.1 - 2.2e-10 40.8 0.1 8.3e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK44414.1 - 3e-08 33.9 0.0 5.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KKK44414.1 - 6.4e-08 32.7 0.0 8e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK44414.1 - 0.0021 18.7 0.0 0.0035 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M1 PF01433.20 KKK44415.1 - 6.7e-18 65.1 1.6 1.1e-17 64.4 1.6 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Aldo_ket_red PF00248.21 KKK44416.1 - 4.9e-28 98.2 0.0 5.7e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.22 KKK44417.1 - 4.4e-08 33.4 0.0 7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KKK44417.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily NMO PF03060.15 KKK44419.1 - 4.2e-09 36.2 0.0 4.5e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK44419.1 - 1.7e-05 24.0 0.0 1.7e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain tRNA-Thr_ED PF08915.11 KKK44420.1 - 4.4e-37 127.2 0.2 5.2e-37 127.0 0.2 1.1 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase Arm-DNA-bind_5 PF17293.2 KKK44420.1 - 0.012 16.0 0.7 0.02 15.3 0.7 1.3 1 0 0 1 1 1 0 Arm DNA-binding domain ABC_tran_2 PF16949.5 KKK44420.1 - 0.13 11.1 2.4 0.09 11.6 0.7 1.6 2 0 0 2 2 2 0 Putative ATP-binding cassette Usp PF00582.26 KKK44421.1 - 4.4e-21 75.9 0.0 5.2e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Sulfatase PF00884.23 KKK44423.1 - 9.7e-88 294.5 0.0 1.4e-87 294.0 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK44423.1 - 0.00028 20.6 0.5 0.0024 17.5 0.5 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KKK44423.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 KKK44423.1 - 0.018 13.6 0.3 0.076 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF229) DUF4994 PF16385.5 KKK44423.1 - 0.05 13.5 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Bactofilin PF04519.13 KKK44425.1 - 2.2e-09 37.5 16.5 0.00033 20.9 6.4 4.0 2 1 1 3 3 3 3 Polymer-forming cytoskeletal Fil_haemagg PF05594.14 KKK44425.1 - 3.6 8.2 8.0 3.6 8.2 3.3 2.8 3 0 0 3 3 3 0 Haemagluttinin repeat Apolipoprotein PF01442.18 KKK44426.1 - 0.00022 21.2 12.2 0.00061 19.7 10.4 2.3 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KKK44426.1 - 0.0012 18.9 0.4 0.014 15.4 0.0 2.6 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus EAP30 PF04157.16 KKK44426.1 - 0.0062 15.8 1.6 0.0062 15.8 1.6 2.0 2 0 0 2 2 2 1 EAP30/Vps36 family PCI PF01399.27 KKK44426.1 - 0.0077 16.7 0.7 0.079 13.5 0.7 2.6 1 1 0 1 1 1 1 PCI domain YtxH PF12732.7 KKK44426.1 - 0.023 15.2 21.2 1.4 9.5 8.8 4.7 2 1 1 3 3 3 0 YtxH-like protein ApoLp-III PF07464.11 KKK44426.1 - 0.023 14.8 14.1 0.022 14.8 7.3 3.3 1 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 KKK44426.1 - 0.22 9.4 8.4 0.056 11.4 3.8 2.0 1 1 1 2 2 2 0 Prominin DUF573 PF04504.14 KKK44426.1 - 0.29 11.8 12.4 0.28 11.8 3.1 3.2 3 1 0 3 3 2 0 Protein of unknown function, DUF573 DUF883 PF05957.13 KKK44426.1 - 0.33 11.6 8.0 2.6 8.7 2.0 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Ribosomal_S6 PF01250.17 KKK44426.1 - 0.44 10.9 0.1 0.44 10.9 0.1 2.9 3 1 0 3 3 3 0 Ribosomal protein S6 Baculo_p24 PF05073.12 KKK44426.1 - 0.44 10.3 4.7 0.19 11.5 1.7 2.0 2 1 0 2 2 2 0 Baculovirus P24 capsid protein TetR_C_13 PF16925.5 KKK44426.1 - 0.85 9.6 3.5 34 4.4 0.1 3.0 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ndc1_Nup PF09531.10 KKK44426.1 - 1.8 7.1 3.5 6.9 5.2 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 KKK44426.1 - 2.7 7.3 11.9 1.8 7.8 9.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EspB PF05802.11 KKK44426.1 - 2.9 7.8 8.6 1.5 8.8 1.2 3.0 3 1 1 4 4 4 0 Enterobacterial EspB protein DUF4085 PF13315.6 KKK44426.1 - 3.3 7.3 15.2 0.41 10.2 9.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) Exonuc_VII_L PF02601.15 KKK44426.1 - 3.7 7.0 8.4 15 5.1 8.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit HAUS-augmin3 PF14932.6 KKK44426.1 - 6.6 6.2 16.6 7.5 6.0 13.1 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 KxDL PF10241.9 KKK44426.1 - 7.7 6.9 11.0 15 6.0 0.1 3.4 3 1 1 4 4 4 0 Uncharacterized conserved protein FliT PF05400.13 KKK44426.1 - 8.6 7.2 10.1 26 5.7 8.8 2.4 1 1 1 2 2 2 0 Flagellar protein FliT PCI PF01399.27 KKK44427.1 - 3.9e-05 24.1 0.6 8.9e-05 23.0 0.2 1.8 2 1 0 2 2 2 1 PCI domain DUF5090 PF17009.5 KKK44427.1 - 0.0065 16.5 1.0 0.008 16.2 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5090) DUF2884 PF11101.8 KKK44427.1 - 0.04 13.4 0.7 0.056 12.9 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Cecropin PF00272.19 KKK44427.1 - 0.058 13.1 1.1 0.22 11.2 0.2 2.2 2 0 0 2 2 2 0 Cecropin family DDRGK PF09756.9 KKK44427.1 - 0.11 12.0 3.1 0.26 10.9 2.1 2.1 1 1 1 2 2 2 0 DDRGK domain MFS_1 PF07690.16 KKK44428.1 - 3.4e-29 101.9 39.0 3.4e-29 101.9 39.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KKK44428.1 - 1.1e-21 76.8 21.2 1.5e-21 76.5 21.2 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 KKK44428.1 - 0.0019 16.8 10.6 0.0019 16.8 10.6 3.1 1 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 KKK44429.1 - 1.4e-28 99.9 39.4 7.2e-25 87.6 32.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KKK44429.1 - 5.6e-23 81.1 10.2 8.3e-23 80.6 10.2 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Vpu PF00558.19 KKK44429.1 - 0.0014 18.4 0.8 0.0058 16.4 0.8 2.1 1 0 0 1 1 1 1 Vpu protein MFS_2 PF13347.6 KKK44429.1 - 0.0052 15.4 35.2 0.022 13.4 12.3 2.9 1 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 KKK44430.1 - 7.4e-35 120.5 70.5 1.9e-28 99.5 40.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KKK44430.1 - 1.2e-24 86.6 20.8 1.5e-24 86.4 20.8 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_2 PF13347.6 KKK44430.1 - 1.2e-07 30.7 50.8 0.00017 20.3 18.9 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein TPR_2 PF07719.17 KKK44434.1 - 9.3e-07 28.5 5.4 1 9.6 0.2 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat tRNA-synt_2e PF02091.15 KKK44434.1 - 0.12 11.6 5.8 0.05 12.8 1.9 2.1 2 0 0 2 2 2 0 Glycyl-tRNA synthetase alpha subunit TPR_1 PF00515.28 KKK44434.1 - 0.14 12.0 10.3 1.3 9.0 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat EH_Signature PF15611.6 KKK44434.1 - 0.27 10.6 3.0 5.4 6.3 0.0 2.8 2 1 1 3 3 3 0 EH_Signature domain TFIIB PF00382.19 KKK44435.1 - 9.1e-30 102.5 1.7 3.3e-16 59.1 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat RB_B PF01857.20 KKK44435.1 - 0.0011 19.0 0.0 0.011 15.8 0.0 2.2 2 1 0 2 2 2 1 Retinoblastoma-associated protein B domain zf-RRN7 PF11781.8 KKK44435.1 - 0.0092 15.7 0.2 0.018 14.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 A2L_zn_ribbon PF08792.10 KKK44435.1 - 0.017 14.8 2.8 0.032 14.0 2.8 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-UBP_var PF17807.1 KKK44435.1 - 0.038 13.7 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger TrmB PF01978.19 KKK44435.1 - 0.23 11.4 1.0 1.8 8.5 0.0 2.7 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB Rep_fac-A_C PF08646.10 KKK44435.1 - 1.7 8.3 4.1 7.6 6.3 0.0 2.9 2 1 1 3 3 3 0 Replication factor-A C terminal domain Gtr1_RagA PF04670.12 KKK44436.1 - 2e-18 66.6 0.0 3.5e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK44436.1 - 2.8e-17 62.7 0.1 6.4e-17 61.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK44436.1 - 4.6e-06 26.2 0.0 1.5e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KKK44436.1 - 7.6e-06 25.6 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44436.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK44436.1 - 0.00016 21.7 0.0 0.00042 20.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NAD_binding_6 PF08030.12 KKK44436.1 - 0.0093 16.1 0.1 0.025 14.7 0.1 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PAP2 PF01569.21 KKK44437.1 - 7.1e-17 61.4 0.7 7.1e-17 61.4 0.7 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKK44437.1 - 5.8e-08 32.6 4.1 5.8e-08 32.6 4.1 2.4 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KKK44437.1 - 0.021 15.4 2.6 0.021 15.4 2.6 3.0 3 1 0 3 3 3 0 PAP2 superfamily C-terminal YjcB PF15940.5 KKK44437.1 - 0.093 12.9 0.7 0.2 11.9 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function AcetylCoA_hyd_C PF13336.6 KKK44439.1 - 2.8e-57 193.0 0.0 5.2e-57 192.1 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KKK44439.1 - 1.7e-26 93.4 0.0 3.4e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Acetyltransf_1 PF00583.25 KKK44439.1 - 8.7e-08 32.4 0.3 2.2e-07 31.1 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KKK44439.1 - 9.2e-05 23.1 0.0 0.00015 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK44439.1 - 0.0018 18.2 0.1 0.0092 15.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK44439.1 - 0.0025 18.2 0.1 0.0068 16.8 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK44439.1 - 0.0038 17.4 0.1 0.0071 16.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 KKK44440.1 - 2.2e-92 309.9 0.0 2.6e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK44440.1 - 4.7e-25 88.4 0.1 8.9e-25 87.5 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KKK44440.1 - 2.8e-23 81.6 3.1 2.8e-23 81.6 3.1 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus HEAT_2 PF13646.6 KKK44441.1 - 8e-73 240.9 0.2 3.2e-15 56.3 0.0 7.4 3 1 4 8 8 8 8 HEAT repeats HEAT PF02985.22 KKK44441.1 - 4.9e-35 116.6 0.0 0.0033 17.6 0.0 12.7 13 0 0 13 13 12 6 HEAT repeat HEAT_PBS PF03130.16 KKK44441.1 - 9.8e-28 94.0 0.0 0.00073 20.0 0.0 10.5 10 1 0 10 10 10 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 KKK44441.1 - 3.3e-13 49.8 0.0 3.5 8.2 0.0 10.1 10 2 1 11 11 11 2 HEAT-like repeat Cnd1 PF12717.7 KKK44441.1 - 7.8e-10 39.0 15.5 0.00037 20.6 1.4 6.5 4 3 2 6 6 6 4 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KKK44441.1 - 8.6e-08 32.0 0.0 0.6 10.2 0.0 7.6 8 1 1 9 9 8 1 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 KKK44441.1 - 2.9e-07 30.9 2.0 1.6 9.1 0.1 5.8 4 2 1 5 5 5 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain Aconitase_B_N PF11791.8 KKK44441.1 - 1.5e-06 28.4 5.6 0.16 12.0 0.0 6.6 4 2 4 8 8 8 1 Aconitate B N-terminal domain Vac14_Fab1_bd PF12755.7 KKK44441.1 - 0.00081 19.9 0.7 56 4.4 0.0 5.9 2 2 3 6 6 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KKK44441.1 - 0.0052 16.4 5.3 0.3 10.6 0.1 4.9 2 1 1 4 4 4 1 CLASP N terminal RICTOR_M PF14666.6 KKK44441.1 - 0.0062 16.3 1.2 15 5.5 0.0 4.8 4 2 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain TPR_20 PF14561.6 KKK44441.1 - 0.019 15.3 7.9 7.4 7.0 0.1 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat Nipped-B_C PF12830.7 KKK44441.1 - 0.02 14.9 0.3 21 5.0 0.0 4.5 5 0 0 5 5 5 0 Sister chromatid cohesion C-terminus Vitellogenin_N PF01347.22 KKK44441.1 - 0.053 11.9 3.4 6.3 5.1 0.1 3.3 4 0 0 4 4 4 0 Lipoprotein amino terminal region V-ATPase_H_C PF11698.8 KKK44441.1 - 0.073 13.2 11.0 5.1 7.2 0.3 5.4 2 1 3 6 6 6 0 V-ATPase subunit H Condensin2nSMC PF12422.8 KKK44441.1 - 0.37 11.0 2.3 4 7.6 0.2 3.7 4 1 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit Robl_LC7 PF03259.17 KKK44442.1 - 0.00031 20.5 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain ALS_ss_C PF10369.9 KKK44442.1 - 0.13 12.4 0.8 4 7.7 0.3 2.2 2 0 0 2 2 2 0 Small subunit of acetolactate synthase z-alpha PF02295.17 KKK44442.1 - 0.18 11.9 0.8 2.1 8.5 0.1 2.5 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain Peptidase_M20 PF01546.28 KKK44443.1 - 1.9e-15 57.1 0.0 2.7e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK44443.1 - 1.3e-10 41.1 0.0 2.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Ras PF00071.22 KKK44444.1 - 1.7e-45 154.6 0.0 1.9e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44444.1 - 4.9e-25 88.1 0.0 6.8e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44444.1 - 3.2e-10 39.8 0.0 3.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 KKK44444.1 - 0.00043 20.1 0.2 0.007 16.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KKK44444.1 - 0.00066 19.1 0.0 0.00093 18.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK44444.1 - 0.0064 16.6 0.0 0.009 16.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK44444.1 - 0.0091 16.3 0.0 0.12 12.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKK44444.1 - 0.0097 15.8 0.1 0.51 10.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KKK44444.1 - 0.09 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KKK44444.1 - 0.092 12.5 0.0 2.3 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KKK44444.1 - 0.13 12.1 0.2 0.24 11.3 0.1 1.5 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KKK44444.1 - 0.16 11.2 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Hydrolase_6 PF13344.6 KKK44445.1 - 4.3e-25 87.8 0.0 1.7e-24 85.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK44445.1 - 1.8e-13 50.3 0.0 3.8e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KKK44445.1 - 3.5e-11 43.8 0.0 6.5e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK44445.1 - 6.6e-09 36.1 5.9 5e-06 26.7 0.0 3.3 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KKK44445.1 - 0.0024 17.5 0.0 0.0076 15.9 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 KKK44445.1 - 0.0067 16.0 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.12 KKK44445.1 - 0.022 14.5 0.5 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase CTP_transf_1 PF01148.20 KKK44446.1 - 0.00036 20.4 10.7 0.00056 19.8 10.7 1.4 1 1 0 1 1 1 1 Cytidylyltransferase family Gag_spuma PF03276.14 KKK44446.1 - 0.3 9.5 0.2 0.4 9.0 0.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PRA1 PF03208.19 KKK44446.1 - 0.46 10.1 9.6 0.47 10.1 4.8 2.2 2 0 0 2 2 2 0 PRA1 family protein K1 PF02960.14 KKK44446.1 - 4.7 7.4 6.1 4.8 7.3 0.8 2.5 2 1 1 3 3 3 0 K1 glycoprotein DUF3566 PF12089.8 KKK44446.1 - 4.7 7.6 7.2 4.5 7.6 0.1 2.6 2 1 1 3 3 3 0 Transmembrane domain of unknown function (DUF3566) Rapsyn_N PF10579.9 KKK44448.1 - 0.0011 19.0 0.5 0.037 14.1 0.0 2.7 1 1 1 2 2 2 1 Rapsyn N-terminal myristoylation and linker region ANAPC3 PF12895.7 KKK44448.1 - 0.0089 16.2 0.1 0.73 10.1 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KKK44448.1 - 0.014 15.2 1.1 1.9 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KKK44448.1 - 0.022 14.9 0.1 7.5 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KKK44448.1 - 0.071 13.4 0.0 25 5.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK44448.1 - 0.16 11.7 1.1 0.38 10.5 0.1 2.2 3 0 0 3 3 3 0 TPR repeat Fis1_TPR_C PF14853.6 KKK44448.1 - 1.6 8.9 5.1 2.5 8.2 0.0 3.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KKK44448.1 - 5.1 7.6 8.9 10 6.7 0.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyoxalase_4 PF13669.6 KKK44449.1 - 9.4e-18 64.5 0.0 5.7e-11 42.7 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 KKK44449.1 - 5.1e-07 29.9 0.1 0.0008 19.6 0.1 3.0 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KKK44449.1 - 0.00022 21.4 0.0 0.66 10.1 0.0 2.9 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KKK44449.1 - 0.019 14.9 1.0 0.18 11.8 0.3 2.5 2 1 0 2 2 2 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KKK44450.1 - 9e-15 54.9 0.0 6.9e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KKK44450.1 - 0.037 14.0 2.1 3.2 7.7 0.1 2.8 2 2 0 2 2 2 0 Glyoxalase-like domain Glyoxalase PF00903.25 KKK44450.1 - 0.061 13.5 0.0 0.36 11.0 0.0 2.3 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2229 PF09989.9 KKK44451.1 - 0.038 13.6 0.0 0.61 9.7 0.0 2.5 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) BcrAD_BadFG PF01869.20 KKK44452.1 - 1.8e-58 198.2 0.2 2.1e-39 135.6 0.6 2.1 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DUF2229 PF09989.9 KKK44452.1 - 1.2e-38 133.0 0.0 3.8e-38 131.3 0.0 2.0 2 0 0 2 2 2 1 CoA enzyme activase uncharacterised domain (DUF2229) AnmK PF03702.14 KKK44452.1 - 0.011 14.8 0.0 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 Anhydro-N-acetylmuramic acid kinase Fer4_12 PF13353.6 KKK44452.1 - 0.027 14.7 0.1 13 6.0 0.0 3.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain MutL PF13941.6 KKK44452.1 - 0.17 10.4 0.5 0.31 9.6 0.1 1.5 2 0 0 2 2 2 0 MutL protein HATPase_c PF02518.26 KKK44457.1 - 3.6e-24 85.4 0.4 2.8e-23 82.6 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KKK44457.1 - 1.9e-21 76.2 0.5 6e-11 42.5 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KKK44457.1 - 2.3e-20 72.7 0.0 7.4e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KKK44457.1 - 5.9e-20 70.8 0.1 9.9e-12 44.6 0.0 3.0 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 KKK44457.1 - 1.2e-11 44.5 0.0 3.8e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KKK44457.1 - 2.8e-10 40.4 0.0 6.5e-05 23.2 0.0 3.2 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KKK44457.1 - 2.3e-09 37.4 0.0 1.3e-06 28.6 0.0 3.2 2 1 0 2 2 2 1 PAS fold PAS_7 PF12860.7 KKK44457.1 - 1.8e-07 31.3 0.0 0.00036 20.7 0.0 3.1 3 0 0 3 3 3 2 PAS fold HATPase_c_3 PF13589.6 KKK44457.1 - 0.036 13.9 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK44457.1 - 0.062 13.3 0.0 0.28 11.2 0.0 2.1 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain Holin_BhlA PF10960.8 KKK44457.1 - 2.8 8.0 7.8 2.1 8.4 0.7 3.9 3 1 1 4 4 4 0 BhlA holin family Hydrolase_4 PF12146.8 KKK44458.1 - 6.9e-51 172.8 0.0 7.9e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK44458.1 - 5.1e-08 33.8 0.0 5.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KKK44458.1 - 1.1e-07 31.8 1.3 0.0039 16.9 0.3 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KKK44458.1 - 8.2e-07 28.8 0.0 0.018 14.6 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KKK44458.1 - 1.8e-06 27.6 0.1 0.0027 17.2 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KKK44458.1 - 1.3e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 KKK44458.1 - 0.00013 21.8 0.6 0.12 12.1 0.0 3.1 2 1 2 4 4 4 2 Phospholipase/Carboxylesterase AXE1 PF05448.12 KKK44458.1 - 0.0013 17.5 0.6 0.27 9.9 0.1 2.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF676 PF05057.14 KKK44458.1 - 0.0023 17.4 2.2 0.0079 15.7 2.2 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF1057 PF06342.12 KKK44458.1 - 0.005 15.9 0.4 0.0061 15.6 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.13 KKK44458.1 - 0.012 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 KKK44458.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.5 1 1 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 KKK44458.1 - 0.035 14.0 0.5 0.11 12.4 0.5 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_2 PF01674.18 KKK44458.1 - 0.075 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_5 PF12695.7 KKK44458.1 - 0.11 12.3 0.6 1.5 8.6 0.2 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KKK44458.1 - 0.11 12.1 1.0 0.22 11.2 0.9 1.6 1 1 0 1 1 1 0 PGAP1-like protein MutS_V PF00488.21 KKK44459.1 - 2.4e-77 259.2 0.4 6.5e-77 257.8 0.4 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK44459.1 - 1.1e-39 136.7 4.1 1.1e-39 136.7 4.1 2.5 2 1 0 2 2 1 1 MutS domain III MutS_I PF01624.20 KKK44459.1 - 1.5e-34 118.6 0.0 4.3e-34 117.1 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KKK44459.1 - 1.6e-23 83.5 2.4 3.2e-23 82.5 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KKK44459.1 - 6e-22 77.8 2.1 6e-22 77.8 2.1 3.3 2 0 0 2 2 2 1 MutS family domain IV MIP-T3_C PF17749.1 KKK44459.1 - 0.0096 15.9 1.7 0.0096 15.9 1.7 2.7 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region UPF0449 PF15136.6 KKK44459.1 - 0.01 16.3 1.6 0.046 14.2 1.6 2.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 AAA_27 PF13514.6 KKK44459.1 - 0.018 14.6 1.2 0.039 13.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KKK44459.1 - 0.098 12.4 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK44459.1 - 0.36 11.3 4.0 0.71 10.4 0.0 3.0 3 0 0 3 3 3 0 ABC transporter MCU PF04678.13 KKK44459.1 - 1.5 8.8 5.7 0.64 10.1 1.3 2.5 3 0 0 3 3 3 0 Mitochondrial calcium uniporter Exonuc_VII_L PF02601.15 KKK44459.1 - 2.9 7.4 10.2 4.6 6.7 6.5 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit LMBR1 PF04791.16 KKK44459.1 - 4.1 6.2 10.6 4.3 6.1 4.0 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF16 PF01519.16 KKK44459.1 - 6.6 7.3 19.5 6.3 7.3 1.2 3.4 2 1 1 3 3 3 0 Protein of unknown function DUF16 GT87 PF09594.10 KKK44460.1 - 4.5e-09 36.4 5.4 5.9e-09 36.0 5.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 87 MTD PF01993.18 KKK44462.1 - 1.2e-27 96.9 0.4 1.3e-27 96.9 0.4 1.0 1 0 0 1 1 1 1 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Topoisom_I PF01028.20 KKK44462.1 - 0.042 13.1 0.1 0.046 13.0 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Gtr1_RagA PF04670.12 KKK44463.1 - 3.2e-21 75.7 0.0 4.3e-21 75.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK44463.1 - 1.5e-08 34.3 0.0 2.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK44463.1 - 5.7e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK44463.1 - 0.00043 19.9 0.1 0.001 18.7 0.1 1.7 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK44463.1 - 0.00073 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 KKK44463.1 - 0.0039 17.7 0.1 0.0061 17.1 0.1 1.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 KKK44463.1 - 0.004 16.7 0.2 1.3 8.6 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KKK44463.1 - 0.0074 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KKK44463.1 - 0.02 15.3 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 KKK44463.1 - 0.021 14.6 0.9 3.6 7.3 0.0 2.8 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KKK44463.1 - 0.033 14.1 0.2 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase HD PF01966.22 KKK44466.1 - 3.5e-05 24.0 0.0 3.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 HD domain zf-3CxxC_2 PF17180.4 KKK44467.1 - 0.011 16.5 3.5 0.024 15.4 3.5 1.5 1 0 0 1 1 1 0 Zinc-binding domain DZR PF12773.7 KKK44467.1 - 0.066 13.2 2.8 0.12 12.4 2.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon HEPN_RiboL-PSP PF18735.1 KKK44467.1 - 0.21 11.5 60.5 0.083 12.8 8.5 5.3 4 2 1 5 5 5 0 RiboL-PSP-HEPN zinc_ribbon_2 PF13240.6 KKK44467.1 - 1 9.2 7.1 1.7 8.4 1.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK44467.1 - 2.2 7.8 6.5 2.3 7.8 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pribosyltran PF00156.27 KKK44468.1 - 6.2e-14 51.8 0.1 7.4e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KKK44468.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase SR1P PF13790.6 KKK44468.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 SR1 protein PfkB PF00294.24 KKK44469.1 - 1.2e-21 77.4 0.0 1.3e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF3781 PF12636.7 KKK44469.1 - 0.029 14.2 0.4 0.049 13.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) Colicin_Pyocin PF01320.18 KKK44469.1 - 0.049 13.7 0.2 0.13 12.4 0.2 1.7 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein Pyr_redox_2 PF07992.14 KKK44471.1 - 2.2e-18 66.5 0.1 5.9e-17 61.8 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.27 KKK44471.1 - 1.2e-13 50.2 23.6 2.2e-09 36.7 5.1 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK44471.1 - 4.4e-13 48.7 13.1 1.6e-07 31.1 4.1 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK44471.1 - 2e-11 44.3 8.2 2e-11 44.3 8.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK44471.1 - 1.4e-10 41.2 17.4 3.6e-08 33.5 8.6 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44471.1 - 6e-10 39.9 8.9 9.6e-05 23.2 0.5 4.0 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK44471.1 - 1.2e-08 35.0 19.5 9e-08 32.1 10.6 2.9 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK44471.1 - 4.4e-08 33.1 8.4 4.4e-08 33.1 8.4 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain FAD_binding_2 PF00890.24 KKK44471.1 - 1.1e-07 31.3 0.1 1.9e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Fer4_2 PF12797.7 KKK44471.1 - 1.8e-06 27.7 19.6 2.8e-05 23.9 3.0 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain FAD_oxidored PF12831.7 KKK44471.1 - 3.3e-06 26.7 0.0 7.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KKK44471.1 - 5.3e-06 26.2 0.2 2.3e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK44471.1 - 8.8e-06 25.9 0.1 2.2e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK44471.1 - 0.00012 21.0 0.4 0.013 14.3 0.1 2.2 1 1 1 2 2 2 1 HI0933-like protein Fer4_17 PF13534.6 KKK44471.1 - 0.00013 22.5 11.6 0.008 16.7 1.6 3.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK44471.1 - 0.00014 22.1 18.6 0.0021 18.4 3.7 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK44471.1 - 0.0003 21.2 17.8 0.00038 20.8 8.7 3.1 3 1 1 4 4 4 2 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 KKK44471.1 - 0.00049 19.5 0.0 0.00089 18.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_3 PF12798.7 KKK44471.1 - 0.00075 20.3 5.5 0.00075 20.3 5.5 4.1 4 0 0 4 4 3 2 4Fe-4S binding domain Pyr_redox_3 PF13738.6 KKK44471.1 - 0.0011 18.3 2.9 0.0095 15.2 0.2 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4342 PF14242.6 KKK44471.1 - 0.0044 17.0 1.2 3.2 7.8 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4342) Fer4_22 PF17179.4 KKK44471.1 - 0.0046 17.8 13.5 0.011 16.5 1.1 3.2 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK44471.1 - 0.0054 17.4 3.8 1.4 9.7 0.2 2.7 2 0 0 2 2 2 2 4Fe-4S single cluster domain Thi4 PF01946.17 KKK44471.1 - 0.0055 16.0 0.0 0.0095 15.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KKK44471.1 - 0.014 14.5 1.5 0.026 13.6 0.2 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 KKK44471.1 - 0.015 14.6 0.0 0.037 13.3 0.0 1.7 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKK44471.1 - 0.03 14.9 0.9 0.25 11.9 0.9 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PCNA_N PF00705.18 KKK44471.1 - 0.031 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain Fer4_13 PF13370.6 KKK44471.1 - 0.099 13.2 12.6 0.33 11.5 1.9 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KKK44471.1 - 0.59 10.3 8.5 0.21 11.8 1.1 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain RNase_H_2 PF13482.6 KKK44472.1 - 5.8e-19 68.7 0.3 9.5e-19 68.0 0.3 1.3 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_lambd_f PF10391.9 KKK44472.1 - 8.4e-07 28.7 0.0 1.1e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 KKK44472.1 - 0.00035 21.1 0.0 0.00072 20.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_exo2 PF10108.9 KKK44472.1 - 0.00076 19.2 0.1 0.002 17.8 0.1 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Cdd1 PF11731.8 KKK44472.1 - 0.0092 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Pathogenicity locus HHH PF00633.23 KKK44472.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF5051 PF16473.5 KKK44472.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like HHH_2 PF12826.7 KKK44472.1 - 0.069 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fae PF08714.11 KKK44475.1 - 4.5e-65 218.4 0.0 5.7e-65 218.1 0.0 1.1 1 0 0 1 1 1 1 Formaldehyde-activating enzyme (Fae) OMPdecase PF00215.24 KKK44475.1 - 3.3e-09 36.7 0.1 5.1e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family UDPG_MGDP_dh_N PF03721.14 KKK44475.1 - 0.049 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2299 PF10061.9 KKK44475.1 - 0.071 12.8 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) Radical_SAM PF04055.21 KKK44476.1 - 1.2e-19 71.3 1.7 4.1e-17 63.1 0.2 3.1 3 1 0 3 3 3 2 Radical SAM superfamily B12-binding PF02310.19 KKK44476.1 - 1.6e-14 54.0 0.0 4.9e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 B12 binding domain SAM_4 PF18017.1 KKK44476.1 - 0.015 15.2 0.0 0.061 13.3 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) PNP_UDP_1 PF01048.20 KKK44479.1 - 1.7e-47 161.7 0.0 1.9e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Beta-Casp PF10996.8 KKK44480.1 - 2.8e-15 56.6 0.0 5.9e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.7 KKK44480.1 - 3.6e-09 36.4 0.0 5.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK44480.1 - 6e-08 32.9 0.0 3.4e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KKK44480.1 - 3.4e-07 30.1 0.0 1.2e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 KKK44480.1 - 4.6e-07 29.4 0.0 1.2e-05 24.9 0.0 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK44480.1 - 0.0031 17.4 0.0 0.044 13.7 0.0 2.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Arena_RNA_pol PF06317.11 KKK44480.1 - 0.0093 13.2 0.0 0.012 12.8 0.0 1.0 1 0 0 1 1 1 1 Arenavirus RNA polymerase DHHA1 PF02272.19 KKK44481.1 - 3.2e-09 37.3 0.2 1e-08 35.7 0.0 2.0 2 0 0 2 2 2 1 DHHA1 domain CDC45 PF02724.14 KKK44481.1 - 0.048 12.0 0.0 0.074 11.3 0.0 1.3 1 0 0 1 1 1 0 CDC45-like protein MCH PF02289.16 KKK44482.1 - 1.9e-104 349.3 0.1 2.1e-104 349.2 0.1 1.0 1 0 0 1 1 1 1 Cyclohydrolase (MCH) Glycos_transf_1 PF00534.20 KKK44485.1 - 8.7e-35 119.8 0.0 1.3e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK44485.1 - 6.5e-20 71.9 0.0 1.8e-19 70.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK44485.1 - 3e-13 50.1 0.0 4.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KKK44485.1 - 4.2e-07 30.3 0.0 9.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KKK44485.1 - 0.097 13.1 0.0 0.32 11.4 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Oxidored_FMN PF00724.20 KKK44486.1 - 8.8e-35 120.6 0.0 1.4e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KKK44486.1 - 0.0014 17.8 0.1 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.6 KKK44486.1 - 0.041 13.3 0.7 0.08 12.4 0.1 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Myco_19_kDa PF05481.12 KKK44486.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Peptidase_M54 PF07998.11 KKK44487.1 - 2.6e-20 73.3 1.8 3.1e-20 73.0 1.3 1.5 1 1 1 2 2 2 1 Peptidase family M54 Presenilin PF01080.17 KKK44488.1 - 5e-23 81.5 27.1 3.7e-12 45.7 0.2 2.1 1 1 1 2 2 2 2 Presenilin GNVR PF13807.6 KKK44488.1 - 4.7 7.2 5.5 3.9 7.4 0.2 3.0 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase ASFV_p27 PF06556.11 KKK44489.1 - 0.017 15.2 0.1 0.019 15.0 0.1 1.3 1 1 0 1 1 1 0 IAP-like protein p27 C-terminus GH97_N PF14508.6 KKK44489.1 - 0.022 14.3 0.1 0.022 14.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal dUTPase_2 PF08761.11 KKK44489.1 - 0.23 11.6 4.7 1.4 9.1 4.7 1.9 1 1 0 1 1 1 0 dUTPase RhaA PF06134.11 KKK44490.1 - 3.7e-180 599.6 0.0 4.4e-180 599.3 0.0 1.0 1 0 0 1 1 1 1 L-rhamnose isomerase (RhaA) FrhB_FdhB_C PF04432.13 KKK44491.1 - 8.7e-12 45.1 0.0 1.3e-08 34.8 0.0 2.4 1 1 1 2 2 2 2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Fer4_10 PF13237.6 KKK44491.1 - 4e-05 23.7 5.1 4e-05 23.7 5.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44491.1 - 8.2e-05 22.3 9.3 0.0008 19.1 1.8 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK44491.1 - 0.0021 18.2 4.8 0.0021 18.2 4.8 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK44491.1 - 0.0023 18.3 0.9 0.0023 18.3 0.9 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_9 PF13187.6 KKK44491.1 - 0.0033 17.6 15.7 0.011 15.9 6.8 2.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK44491.1 - 0.0048 17.4 9.5 0.008 16.7 1.4 3.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK44491.1 - 0.0049 16.9 2.0 0.0049 16.9 2.0 3.1 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_7 PF12838.7 KKK44491.1 - 0.0082 16.7 10.1 0.11 13.1 9.7 2.7 2 1 2 4 4 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44491.1 - 0.019 15.1 1.4 0.019 15.1 1.4 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK44491.1 - 0.054 14.0 8.4 0.13 12.8 3.4 2.7 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_16 PF13484.6 KKK44491.1 - 0.75 10.8 9.9 0.38 11.7 2.0 3.0 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 KKK44491.1 - 1.1 9.8 12.4 0.26 11.8 2.2 2.7 2 1 2 4 4 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK44491.1 - 5.1 8.3 16.5 1.3 10.2 4.7 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Ras PF00071.22 KKK44492.1 - 3.1e-39 134.2 0.0 3.6e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44492.1 - 1e-25 90.3 0.0 1.5e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44492.1 - 5.3e-10 39.0 0.1 5.6e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK44492.1 - 0.00048 19.6 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK44492.1 - 0.0011 19.1 0.0 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK44492.1 - 0.0081 16.6 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KKK44492.1 - 0.0092 15.3 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KKK44492.1 - 0.012 15.5 0.2 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KKK44492.1 - 0.016 15.3 0.1 0.017 15.2 0.1 1.4 1 1 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.27 KKK44492.1 - 0.019 14.5 0.1 3.9 7.0 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KKK44492.1 - 0.033 13.9 0.2 0.042 13.6 0.2 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK44492.1 - 0.034 14.5 0.0 0.98 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KKK44492.1 - 0.062 13.2 1.1 0.26 11.2 0.6 2.0 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KKK44492.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KKK44492.1 - 0.1 12.9 0.3 0.24 11.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KKK44492.1 - 0.11 12.3 0.5 0.33 10.7 0.5 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KKK44492.1 - 0.2 12.2 0.6 0.25 11.9 0.6 1.6 1 1 0 1 1 1 0 ABC transporter MoCF_biosynth PF00994.24 KKK44496.1 - 2.4e-05 24.0 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 KKK44496.1 - 0.0078 16.3 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 Damage-inducible protein CinA KH domain AIRS_C PF02769.22 KKK44497.1 - 3.9e-19 69.3 0.0 7.5e-19 68.4 0.0 1.4 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain Alba PF01918.21 KKK44501.1 - 5e-12 45.5 0.4 6.4e-12 45.1 0.4 1.2 1 0 0 1 1 1 1 Alba N6_Mtase PF02384.16 KKK44502.1 - 1.7e-32 112.9 0.1 2.8e-32 112.3 0.1 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 KKK44502.1 - 0.0011 18.7 0.0 0.005 16.6 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 KKK44502.1 - 0.035 13.6 0.0 2.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase small domain Sterile PF03015.19 KKK44502.1 - 0.2 11.9 1.8 0.7 10.2 0.0 2.7 2 1 1 3 3 3 0 Male sterility protein AAA_31 PF13614.6 KKK44506.1 - 7.7e-23 81.3 0.8 7.7e-23 81.3 0.8 1.6 1 1 1 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KKK44506.1 - 0.00081 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ CbiA PF01656.23 KKK44506.1 - 0.00094 19.2 0.9 0.019 15.0 0.9 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KKK44506.1 - 0.0055 16.0 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ NucS PF01939.16 KKK44508.1 - 1.1e-08 34.7 0.3 1.4e-08 34.4 0.3 1.0 1 0 0 1 1 1 1 Endonuclease NucS PDDEXK_9 PF08011.11 KKK44508.1 - 0.0001 22.1 0.1 0.00019 21.3 0.1 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily YhcG_C PF06250.11 KKK44508.1 - 0.0016 18.3 0.1 0.0022 17.8 0.1 1.4 1 0 0 1 1 1 1 YhcG PDDEXK nuclease domain PDDEXK_3 PF13366.6 KKK44508.1 - 0.0067 16.8 0.6 0.02 15.3 0.1 1.9 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF2800 PF10926.8 KKK44508.1 - 0.06 12.6 0.0 0.084 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) DUF3948 PF13134.6 KKK44509.1 - 1.4 8.7 6.7 0.6 9.8 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) DNA_binding_1 PF01035.20 KKK44510.1 - 7e-28 96.6 0.1 1.5e-27 95.5 0.0 1.5 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3888 PF13027.6 KKK44510.1 - 0.029 14.8 0.1 0.054 13.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3888) Alpha-L-AF_C PF06964.12 KKK44511.1 - 2.1e-23 83.3 0.0 2.9e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_30C PF17189.4 KKK44511.1 - 0.074 13.3 0.2 0.5 10.6 0.0 2.4 2 1 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain SLT_beta PF02258.16 KKK44511.1 - 0.075 13.1 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Shiga-like toxin beta subunit Exo_endo_phos PF03372.23 KKK44512.1 - 1.4e-11 44.3 0.3 2.1e-11 43.8 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PhnA_Zn_Ribbon PF08274.12 KKK44513.1 - 0.006 16.5 0.4 3.3 7.7 0.1 2.3 2 0 0 2 2 2 2 PhnA Zinc-Ribbon DUF2197 PF09963.9 KKK44513.1 - 0.0074 16.5 1.1 2.2 8.6 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) zf-C3HC4_3 PF13920.6 KKK44513.1 - 0.0095 15.8 2.3 0.039 13.8 2.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cys_rich_KTR PF14205.6 KKK44513.1 - 0.01 15.6 1.4 0.16 11.8 1.4 2.3 1 1 0 1 1 1 0 Cysteine-rich KTR zinc_ribbon_15 PF17032.5 KKK44513.1 - 0.011 16.5 1.3 0.012 16.4 1.3 1.1 1 0 0 1 1 1 0 zinc-ribbon family TFIIS_C PF01096.18 KKK44513.1 - 0.012 15.5 3.4 0.13 12.2 0.5 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 KKK44513.1 - 0.017 15.2 1.1 0.029 14.5 1.1 1.4 1 1 0 1 1 1 0 Zinc ribbon domain Lar_restr_allev PF14354.6 KKK44513.1 - 0.041 14.3 0.2 8.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Ogr_Delta PF04606.12 KKK44513.1 - 0.042 13.8 1.4 6.5 6.8 0.2 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_S27e PF01667.17 KKK44513.1 - 0.052 13.3 0.8 8.4 6.2 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 PADR1 PF08063.12 KKK44513.1 - 0.054 13.3 0.3 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 PADR1 (NUC008) domain DUF866 PF05907.13 KKK44513.1 - 0.057 13.3 1.1 0.069 13.1 1.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) DUF4428 PF14471.6 KKK44513.1 - 0.075 13.0 1.3 1.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Prok-RING_4 PF14447.6 KKK44513.1 - 0.21 11.4 4.1 2.8 7.9 4.1 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 KKK44513.1 - 0.27 11.8 3.8 6.8 7.3 0.5 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain NucS PF01939.16 KKK44514.1 - 0.031 13.6 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS PTS_IIB PF02302.17 KKK44514.1 - 0.034 14.8 0.7 0.096 13.4 0.4 1.8 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit SfsA PF03749.13 KKK44514.1 - 0.045 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain PDDEXK_4 PF14281.6 KKK44514.1 - 0.1 12.7 1.9 0.11 12.6 1.9 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF2695 PF10905.8 KKK44515.1 - 0.12 12.7 0.1 0.41 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) TadE PF07811.12 KKK44515.1 - 0.15 12.4 1.0 0.31 11.4 1.0 1.5 1 0 0 1 1 1 0 TadE-like protein DSPc PF00782.20 KKK44516.1 - 0.041 13.7 0.1 0.041 13.7 0.1 1.0 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain HD PF01966.22 KKK44517.1 - 1.9e-11 44.2 0.0 5.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 HD domain N6-adenineMlase PF10237.9 KKK44517.1 - 2.7e-11 43.5 0.0 4.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF43 PF01861.16 KKK44517.1 - 7.3e-06 25.4 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain CDC48_N PF02359.18 KKK44519.1 - 2.5e-17 62.8 1.2 6.1e-17 61.6 0.7 1.8 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 KKK44519.1 - 2.7e-06 27.1 0.0 8.1e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Myotub-related PF06602.14 KKK44519.1 - 0.0014 17.6 0.2 0.0017 17.4 0.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Rho_RNA_bind PF07497.12 KKK44519.1 - 0.017 15.0 0.1 0.076 12.9 0.1 2.2 1 1 1 2 2 2 0 Rho termination factor, RNA-binding domain UFD1 PF03152.14 KKK44519.1 - 0.02 14.4 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Molydop_binding PF01568.21 KKK44519.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Acetyltransf_1 PF00583.25 KKK44520.1 - 4.5e-11 43.0 0.1 5.3e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK44520.1 - 1.7e-07 31.2 0.0 1.9e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK44520.1 - 2e-06 28.2 0.0 2.2e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK44520.1 - 0.001 19.1 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK44520.1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KKK44520.1 - 0.0029 17.5 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase HECA PF15353.6 KKK44520.1 - 0.061 13.6 0.0 0.073 13.3 0.0 1.2 1 0 0 1 1 1 0 Headcase protein family homologue PanZ PF12568.8 KKK44520.1 - 0.062 13.0 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 KKK44520.1 - 0.066 13.4 0.1 0.072 13.2 0.1 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK44521.1 - 2e-05 24.8 0.1 3.4e-05 24.0 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KKK44521.1 - 0.0001 22.6 0.4 0.0002 21.7 0.1 1.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK44521.1 - 0.00035 20.5 0.0 0.00076 19.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RNaseH_C PF09293.10 KKK44521.1 - 0.0042 17.4 0.2 0.0082 16.5 0.2 1.5 1 0 0 1 1 1 1 T4 RNase H, C terminal FR47 PF08445.10 KKK44521.1 - 0.0042 17.0 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KKK44521.1 - 0.028 14.5 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3847 PF12958.7 KKK44522.1 - 0.042 13.9 0.1 3.3 7.9 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) CttA_N PF18244.1 KKK44523.1 - 0.031 14.7 0.2 0.059 13.8 0.2 1.5 1 0 0 1 1 1 0 Cellulose-binding protein CttA N-terminal domain DUF1624 PF07786.12 KKK44524.1 - 0.0021 17.6 1.3 0.0026 17.4 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) DUF2207 PF09972.9 KKK44524.1 - 0.0056 15.5 2.7 0.0067 15.3 2.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SLATT_4 PF18186.1 KKK44524.1 - 0.074 12.7 0.2 0.095 12.3 0.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 TPR_19 PF14559.6 KKK44526.1 - 2.9e-14 53.3 0.0 0.0018 18.8 0.4 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK44526.1 - 1.1e-08 34.6 6.7 0.026 14.6 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK44526.1 - 3.9e-08 32.9 7.2 0.068 13.4 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK44526.1 - 8.1e-08 32.4 0.1 1.7e-05 25.0 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK44526.1 - 1.4e-07 31.7 0.0 8.4 7.5 0.1 6.0 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KKK44526.1 - 1.7e-07 30.8 12.9 0.063 13.1 0.4 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 KKK44526.1 - 4e-06 26.0 0.7 0.00017 20.7 0.0 2.6 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 KKK44526.1 - 0.00042 20.5 1.1 0.15 12.5 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KKK44526.1 - 0.00056 20.4 0.0 19 6.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KKK44526.1 - 0.0013 18.9 0.0 0.025 14.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK44526.1 - 0.0013 18.9 0.2 0.16 12.2 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KKK44526.1 - 0.0028 17.5 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 KKK44526.1 - 0.0058 16.9 0.0 0.13 12.7 0.2 3.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KKK44526.1 - 0.015 14.5 0.1 0.088 12.0 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KKK44526.1 - 0.033 14.2 0.0 18 5.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KKK44526.1 - 0.19 12.4 0.0 35 5.2 0.0 3.3 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK44526.1 - 3.1 7.6 8.2 19 5.1 0.2 4.1 5 0 0 5 5 4 0 TPR repeat Big_7 PF17957.1 KKK44527.1 - 3.1e-13 50.3 20.1 5.6e-10 39.9 6.8 3.7 4 1 0 4 4 4 2 Bacterial Ig domain Exo_endo_phos PF03372.23 KKK44527.1 - 1.4e-08 34.5 0.8 2.1e-08 34.0 0.8 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Big_3_3 PF13750.6 KKK44527.1 - 0.00061 19.5 0.6 0.0019 17.8 0.2 2.0 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 3) HYR PF02494.16 KKK44527.1 - 0.13 12.6 2.4 7.7 6.9 0.9 3.3 2 1 0 2 2 2 0 HYR domain Metallophos PF00149.28 KKK44528.1 - 2.9e-14 54.0 2.8 7.7e-14 52.7 2.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK44528.1 - 1.5e-09 38.3 0.0 3e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_23 PF13476.6 KKK44529.1 - 8.2e-06 26.5 26.2 8.2e-06 26.5 26.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 KKK44529.1 - 6.5e-05 22.8 37.1 9.7e-05 22.2 37.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 KKK44529.1 - 8.6e-05 22.2 0.0 8.6e-05 22.2 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.6 KKK44529.1 - 0.00019 21.1 0.1 0.00071 19.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rep_fac_C PF08542.11 KKK44529.1 - 0.0014 19.0 0.9 0.014 15.8 0.4 2.2 1 1 1 2 2 2 1 Replication factor C C-terminal domain SMC_N PF02463.19 KKK44529.1 - 0.045 13.2 3.9 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KKK44529.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1844 PF08899.11 KKK44529.1 - 0.16 12.3 3.0 9.8 6.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) Exonuc_VII_L PF02601.15 KKK44529.1 - 1.6 8.3 8.4 6.8 6.2 9.3 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.11 KKK44529.1 - 10 6.3 9.3 3.1 7.9 1.1 2.9 3 0 0 3 3 3 0 Streptococcal surface antigen repeat Z1 PF10593.9 KKK44530.1 - 0.54 9.7 3.9 17 4.8 1.7 2.4 2 0 0 2 2 2 0 Z1 domain PLDc_2 PF13091.6 KKK44532.1 - 1.1e-09 38.2 0.1 1.6e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 PLD-like domain GIY-YIG PF01541.24 KKK44532.1 - 1.9e-06 28.0 0.4 5.8e-06 26.5 0.4 1.9 1 0 0 1 1 1 1 GIY-YIG catalytic domain PMT_4TMC PF16192.5 KKK44534.1 - 0.33 10.5 9.2 0.78 9.3 9.2 1.6 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase DUF2070 PF09843.9 KKK44534.1 - 4.7 5.4 15.9 5.8 5.1 15.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Adeno_E3B PF03376.14 KKK44534.1 - 6.2 7.1 12.5 2.6 8.4 4.0 2.4 2 1 0 2 2 2 0 Adenovirus E3B protein DHHC PF01529.20 KKK44534.1 - 9 6.4 8.0 15 5.7 8.0 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase UCR_Fe-S_N PF10399.9 KKK44538.1 - 0.028 13.8 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SpoU_methylase PF00588.19 KKK44539.1 - 7.1e-28 97.6 0.0 1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Methyltrn_RNA_4 PF09936.9 KKK44539.1 - 0.0031 17.4 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 SAM-dependent RNA methyltransferase Filament PF00038.21 KKK44541.1 - 0.00048 19.8 0.8 0.00084 19.0 0.8 1.4 1 1 0 1 1 1 1 Intermediate filament protein Sigma70_r4_2 PF08281.12 KKK44541.1 - 0.0016 18.1 0.0 0.026 14.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 FeoC PF09012.10 KKK44541.1 - 0.0052 16.8 0.1 0.97 9.6 0.0 3.2 3 1 0 3 3 3 1 FeoC like transcriptional regulator HTH_11 PF08279.12 KKK44541.1 - 0.0084 16.0 0.0 0.73 9.8 0.0 2.4 2 0 0 2 2 2 1 HTH domain UPF0122 PF04297.14 KKK44541.1 - 0.0088 16.3 1.4 0.019 15.2 0.2 2.1 2 1 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like Sigma70_r4 PF04545.16 KKK44541.1 - 0.012 15.1 0.0 0.041 13.4 0.0 2.0 2 1 0 2 2 2 0 Sigma-70, region 4 LysM PF01476.20 KKK44541.1 - 0.02 15.0 0.0 0.08 13.0 0.0 2.0 2 0 0 2 2 2 0 LysM domain RHH_1 PF01402.21 KKK44541.1 - 0.031 14.2 0.1 0.098 12.6 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family COMPASS-Shg1 PF05205.12 KKK44541.1 - 0.037 14.7 0.6 0.052 14.3 0.6 1.4 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 HTH_6 PF01418.17 KKK44541.1 - 0.038 14.0 0.2 4.5 7.3 0.1 2.5 1 1 2 3 3 3 0 Helix-turn-helix domain, rpiR family ParG PF09274.10 KKK44541.1 - 0.062 13.4 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 ParG RPA_C PF08784.11 KKK44541.1 - 0.078 13.6 0.8 2.1 9.1 0.3 2.2 1 1 1 2 2 2 0 Replication protein A C terminal Serglycin PF04360.12 KKK44541.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Serglycin Acetyltransf_9 PF13527.7 KKK44544.1 - 1e-28 99.9 0.4 3.2e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_17 PF17668.1 KKK44544.1 - 3.5e-08 34.3 0.0 3.3e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK44544.1 - 0.002 18.5 0.1 0.0049 17.3 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SRX PF09201.10 KKK44544.1 - 0.026 14.3 0.3 0.038 13.8 0.3 1.3 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit Acetyltransf_1 PF00583.25 KKK44544.1 - 0.076 13.2 0.1 0.24 11.7 0.0 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family DUF1048 PF06304.11 KKK44544.1 - 0.27 11.7 2.5 0.33 11.4 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) RNA_pol_Rpb6 PF01192.22 KKK44546.1 - 1.2e-11 44.3 0.0 2.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 PadR PF03551.14 KKK44547.1 - 0.0094 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_45 PF14947.6 KKK44547.1 - 0.029 14.3 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix HSDR_N PF04313.14 KKK44551.1 - 0.0027 17.7 0.6 0.0064 16.5 0.1 1.8 1 1 1 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) PDCD2_C PF04194.13 KKK44551.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Ras PF00071.22 KKK44552.1 - 1.6e-13 50.6 0.0 1.7e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44552.1 - 2.9e-12 46.9 0.0 3.1e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44552.1 - 0.00061 19.3 0.0 0.00063 19.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK44552.1 - 0.0065 16.5 0.0 0.0069 16.5 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase CPT PF07931.12 KKK44552.1 - 0.0067 16.3 0.0 0.0078 16.1 0.0 1.1 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 KKK44552.1 - 0.023 14.0 0.0 0.024 13.9 0.0 1.0 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KKK44552.1 - 0.033 14.6 0.0 0.033 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 KKK44552.1 - 0.088 12.2 0.0 0.098 12.0 0.0 1.0 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PRK PF00485.18 KKK44552.1 - 0.11 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 KKK44552.1 - 0.15 11.8 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 AAA domain Amidase PF01425.21 KKK44555.1 - 1e-157 525.7 0.0 1.2e-157 525.5 0.0 1.0 1 0 0 1 1 1 1 Amidase GatB_N PF02934.15 KKK44556.1 - 8.7e-68 228.7 0.0 9.6e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 GatB/GatE catalytic domain TFIIB PF00382.19 KKK44559.1 - 2.8e-30 104.2 0.0 1.1e-19 70.2 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.23 KKK44559.1 - 2.7e-09 36.8 0.4 0.00038 20.2 0.7 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.12 KKK44559.1 - 7.7e-08 31.7 0.8 1.7e-07 30.6 0.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 KKK44559.1 - 2.3e-05 24.4 0.4 0.00026 21.0 0.2 2.1 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain TFIIB_C_1 PF18542.1 KKK44559.1 - 0.0027 17.7 0.9 0.0074 16.3 0.4 1.9 2 0 0 2 2 2 1 Transcription factor IIB C-terminal module 1 A2L_zn_ribbon PF08792.10 KKK44559.1 - 0.0071 16.0 0.8 0.013 15.2 0.8 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain HTH_9 PF08221.11 KKK44559.1 - 0.016 15.3 0.2 0.082 13.0 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Rrf2 PF02082.20 KKK44559.1 - 0.073 13.4 0.6 1.7 9.1 0.1 2.4 3 0 0 3 3 2 0 Transcriptional regulator Auto_anti-p27 PF06677.12 KKK44559.1 - 0.091 12.9 0.5 0.16 12.1 0.5 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cyclin_C PF02984.19 KKK44559.1 - 0.091 12.8 0.0 0.68 10.0 0.0 2.0 1 1 1 2 2 2 0 Cyclin, C-terminal domain Lar_restr_allev PF14354.6 KKK44559.1 - 0.45 10.9 2.0 0.6 10.5 0.1 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar DnaJ_C PF01556.18 KKK44560.1 - 1.8e-38 132.0 0.5 2.9e-38 131.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KKK44560.1 - 4.2e-27 94.1 2.3 4.2e-27 94.1 2.3 1.7 2 0 0 2 2 2 1 DnaJ domain HSP70 PF00012.20 KKK44561.1 - 2.4e-216 719.6 9.8 9.3e-214 711.0 9.8 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KKK44561.1 - 1.3e-14 53.8 3.9 3.8e-14 52.2 3.9 1.8 1 1 0 1 1 1 1 MreB/Mbl protein TBCA PF02970.16 KKK44561.1 - 0.0046 17.3 5.6 0.016 15.5 5.6 2.0 1 0 0 1 1 1 1 Tubulin binding cofactor A DDR PF08841.10 KKK44561.1 - 0.0064 15.5 0.2 0.012 14.6 0.2 1.4 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 KKK44561.1 - 0.012 16.0 7.9 0.13 12.7 0.4 3.8 3 2 0 3 3 3 0 Cell division protein FtsA DUF1090 PF06476.12 KKK44561.1 - 0.02 15.0 5.8 0.046 13.8 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) SOAR PF16533.5 KKK44561.1 - 0.38 10.7 2.0 1.2 9.1 2.0 1.9 1 0 0 1 1 1 0 STIM1 Orai1-activating region GrpE PF01025.19 KKK44563.1 - 3.4e-34 117.9 11.8 6e-33 113.8 11.8 2.0 1 1 0 1 1 1 1 GrpE BORCS8 PF10167.9 KKK44563.1 - 0.05 13.5 0.3 2.7 7.9 0.3 2.3 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 8 DivIC PF04977.15 KKK44563.1 - 0.42 10.4 7.3 0.07 12.9 2.8 2.0 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 KKK44563.1 - 4 7.6 10.5 0.3 11.2 1.0 2.9 2 1 1 3 3 3 0 bZIP transcription factor CARDB PF07705.11 KKK44567.1 - 3.2e-36 123.7 1.4 3.8e-12 46.4 0.2 3.2 3 0 0 3 3 3 3 CARDB Albumin_I_a PF16720.5 KKK44567.1 - 0.32 10.9 2.9 3.4 7.6 0.1 3.0 3 0 0 3 3 3 0 Albumin I chain a Endomucin PF07010.12 KKK44568.1 - 0.19 11.7 0.6 11 5.9 1.0 2.0 1 1 1 2 2 2 0 Endomucin Pox_A14 PF05767.12 KKK44568.1 - 4.4 7.5 10.5 1.2 9.3 5.7 2.1 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF3464 PF11947.8 KKK44569.1 - 0.2 11.4 0.7 0.22 11.2 0.7 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4006 PF13179.6 KKK44569.1 - 3.4 7.6 6.9 2.2 8.2 1.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Oleosin PF01277.17 KKK44570.1 - 0.015 15.0 5.0 0.017 14.9 5.0 1.1 1 0 0 1 1 1 0 Oleosin DUF2207 PF09972.9 KKK44570.1 - 0.28 9.9 5.5 0.28 9.9 5.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3784 PF12650.7 KKK44570.1 - 0.45 10.7 8.9 0.59 10.4 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Tetraspanin PF00335.20 KKK44570.1 - 0.46 10.2 3.3 0.49 10.1 3.3 1.0 1 0 0 1 1 1 0 Tetraspanin family PadR PF03551.14 KKK44571.1 - 5.5e-07 29.5 0.1 1.7e-06 27.9 0.1 1.9 1 1 1 2 2 2 1 Transcriptional regulator PadR-like family HxlR PF01638.17 KKK44571.1 - 0.00055 19.7 0.2 0.0015 18.3 0.1 1.9 1 1 0 1 1 1 1 HxlR-like helix-turn-helix Replic_Relax PF13814.6 KKK44571.1 - 0.0025 17.9 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 Replication-relaxation HTH_34 PF13601.6 KKK44571.1 - 0.022 14.9 0.2 0.042 14.0 0.2 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_11 PF08279.12 KKK44571.1 - 0.028 14.4 1.8 0.055 13.4 0.1 2.1 2 0 0 2 2 2 0 HTH domain B-block_TFIIIC PF04182.12 KKK44571.1 - 0.052 13.7 3.3 0.34 11.1 0.3 2.6 2 1 1 3 3 3 0 B-block binding subunit of TFIIIC DUF3347 PF11827.8 KKK44571.1 - 0.098 12.8 2.6 0.11 12.6 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Nod1 PF17114.5 KKK44571.1 - 0.36 11.0 6.5 5.3 7.2 0.2 2.1 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 TusA PF01206.17 KKK44572.1 - 1e-17 63.7 0.0 1.1e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA Aminotran_5 PF00266.19 KKK44573.1 - 2e-74 250.8 0.0 2.4e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK44573.1 - 3.6e-10 39.5 0.0 6.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK44573.1 - 2e-08 33.9 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KKK44573.1 - 7.4e-05 21.4 0.1 0.00011 20.9 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 KKK44573.1 - 0.0001 21.2 0.0 0.00031 19.6 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 KKK44573.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Shikimate_DH PF01488.20 KKK44573.1 - 0.022 14.8 0.3 0.022 14.8 0.3 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Asp_decarbox PF02261.16 KKK44573.1 - 0.1 12.6 0.3 0.36 10.8 0.1 2.0 2 0 0 2 2 2 0 Aspartate decarboxylase GDC-P PF02347.16 KKK44573.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein NifU_N PF01592.16 KKK44574.1 - 1.4e-46 157.8 0.2 2.4e-46 157.1 0.2 1.4 1 0 0 1 1 1 1 NifU-like N terminal domain Pyr_redox PF00070.27 KKK44574.1 - 7.2e-05 23.3 0.1 0.00014 22.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK44574.1 - 0.00035 19.9 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KKK44574.1 - 0.0013 17.3 0.0 0.002 16.7 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NIBRIN_BRCT_II PF16508.5 KKK44574.1 - 0.07 13.5 0.1 0.29 11.5 0.1 2.0 1 1 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein PTS_IIB PF02302.17 KKK44574.1 - 0.072 13.8 2.4 7.1 7.4 0.2 3.3 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit Ras PF00071.22 KKK44575.1 - 7.5e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Ras family zf-ribbon_3 PF13248.6 KKK44575.1 - 0.00083 18.7 2.5 0.0013 18.0 2.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK44575.1 - 0.0061 16.6 0.1 0.0088 16.0 0.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK44575.1 - 0.032 15.0 0.6 0.055 14.2 0.6 1.4 1 1 0 1 1 1 0 zinc-ribbon family Cyclophil_like PF04126.13 KKK44576.1 - 1.3e-22 79.8 0.0 1.5e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin-like Cyclophil_like2 PF18050.1 KKK44576.1 - 5.5e-05 23.1 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin-like family DUF3830 PF12903.7 KKK44576.1 - 0.0079 15.9 0.0 0.041 13.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3830) Pyr_redox_2 PF07992.14 KKK44577.1 - 6.5e-58 196.3 0.3 1e-57 195.6 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 KKK44577.1 - 3.2e-31 108.0 0.0 1.2e-13 51.5 0.0 3.9 4 0 0 4 4 4 2 Rhodanese-like domain Pyr_redox PF00070.27 KKK44577.1 - 1.7e-16 60.5 2.5 9.9e-16 58.1 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK44577.1 - 7.4e-15 55.2 0.7 1.3e-14 54.3 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 KKK44577.1 - 2.4e-10 40.1 0.4 1.4e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TusA PF01206.17 KKK44577.1 - 3.4e-09 36.4 0.0 8.8e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Sulfurtransferase TusA NAD_binding_8 PF13450.6 KKK44577.1 - 1.1e-06 28.8 1.6 0.039 14.2 0.0 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KKK44577.1 - 4.8e-05 23.4 0.7 1.2 9.1 0.2 4.0 2 2 2 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KKK44577.1 - 9.2e-05 21.7 0.1 0.43 9.6 0.1 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 KKK44577.1 - 0.00017 21.3 1.4 0.65 9.5 0.1 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK44577.1 - 0.00049 18.9 2.6 0.91 8.2 0.0 3.8 3 1 1 4 4 4 2 HI0933-like protein DUF1188 PF06690.11 KKK44577.1 - 0.0011 18.6 0.9 0.0049 16.5 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) FAD_binding_3 PF01494.19 KKK44577.1 - 0.0049 16.2 0.6 0.052 12.8 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 KKK44577.1 - 0.0076 16.7 0.1 0.075 13.5 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding ATPase_2 PF01637.18 KKK44577.1 - 0.012 15.6 0.2 0.036 14.0 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Shikimate_DH PF01488.20 KKK44577.1 - 0.016 15.3 0.6 2.8 8.0 0.7 3.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 KKK44577.1 - 0.02 14.1 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 KKK44577.1 - 0.045 14.0 0.5 0.35 11.1 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 KKK44577.1 - 0.055 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KKK44577.1 - 0.057 12.6 1.3 1.1 8.5 0.2 2.9 3 0 0 3 3 3 0 Thi4 family AlaDh_PNT_C PF01262.21 KKK44577.1 - 0.12 11.6 0.5 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TBK1_ULD PF18396.1 KKK44577.1 - 0.18 11.7 0.0 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Amino_oxidase PF01593.24 KKK44577.1 - 0.21 10.8 0.0 0.67 9.2 0.0 1.7 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KKK44577.1 - 0.46 9.5 1.7 25 3.8 0.2 2.8 3 0 0 3 3 3 0 FAD binding domain Rubrerythrin PF02915.17 KKK44578.1 - 9.2e-30 103.8 4.1 1.1e-29 103.5 4.1 1.1 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 KKK44578.1 - 2e-06 27.8 1.2 2.6e-06 27.4 1.2 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubredoxin PF00301.20 KKK44578.1 - 0.0024 17.8 0.5 0.0024 17.8 0.5 2.2 1 1 1 2 2 2 1 Rubredoxin HypA PF01155.19 KKK44578.1 - 0.0092 16.0 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4379 PF14311.6 KKK44578.1 - 0.021 15.2 2.5 0.33 11.3 2.5 2.3 1 1 0 1 1 1 0 Probable Zinc-ribbon domain Galactosyl_T PF01762.21 KKK44578.1 - 0.041 13.7 0.6 0.095 12.5 0.1 1.9 1 1 1 2 2 2 0 Galactosyltransferase zf-RanBP PF00641.18 KKK44578.1 - 0.065 12.6 5.6 0.49 9.8 1.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PHD_4 PF16866.5 KKK44578.1 - 0.1 12.7 3.3 0.22 11.7 3.3 1.6 1 0 0 1 1 1 0 PHD-finger Rubredoxin_2 PF18073.1 KKK44578.1 - 0.22 11.3 3.7 4.4 7.1 0.7 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain TFIIS_C PF01096.18 KKK44578.1 - 0.25 11.2 2.6 1.3 8.9 0.5 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) PhnA_Zn_Ribbon PF08274.12 KKK44578.1 - 0.67 9.9 5.5 1.8 8.6 0.3 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Desulfoferrodox PF01880.18 KKK44579.1 - 2.5e-24 85.7 0.0 3.5e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Desulfoferrodoxin Desulfoferrod_N PF06397.12 KKK44579.1 - 6.4e-11 41.7 2.7 6.4e-11 41.7 2.7 1.9 2 0 0 2 2 2 1 Desulfoferrodoxin, N-terminal domain Ligase_CoA PF00549.19 KKK44579.1 - 0.068 13.0 0.1 0.093 12.5 0.1 1.1 1 0 0 1 1 1 0 CoA-ligase CitMHS PF03600.16 KKK44580.1 - 2.4e-19 69.7 16.1 3.5e-19 69.1 16.1 1.3 1 0 0 1 1 1 1 Citrate transporter DctM PF06808.12 KKK44580.1 - 5.2 5.8 22.9 8.2 5.1 22.9 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component CitMHS PF03600.16 KKK44581.1 - 1.6e-07 30.9 0.0 1.6e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Citrate transporter ArsB PF02040.15 KKK44581.1 - 0.00061 19.2 0.0 0.00065 19.1 0.0 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein HTH_24 PF13412.6 KKK44584.1 - 1.7e-19 69.1 0.6 2.4e-09 36.6 0.5 2.6 3 0 0 3 3 2 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK44584.1 - 3.2e-14 52.5 0.0 6.5e-06 25.9 0.0 2.6 3 0 0 3 3 2 2 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 KKK44584.1 - 2.9e-07 30.3 0.2 0.019 14.9 0.4 2.5 2 0 0 2 2 2 2 HTH domain HTH_5 PF01022.20 KKK44584.1 - 1e-06 28.5 0.1 3e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 KKK44584.1 - 6.3e-06 26.0 1.4 7.1e-05 22.7 0.1 2.7 3 0 0 3 3 3 1 MarR family MarR_2 PF12802.7 KKK44584.1 - 1.2e-05 25.1 0.0 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_9 PF08221.11 KKK44584.1 - 3.4e-05 23.9 1.1 0.41 10.8 0.1 3.7 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_36 PF13730.6 KKK44584.1 - 3.8e-05 23.6 0.1 0.013 15.4 0.1 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain B-block_TFIIIC PF04182.12 KKK44584.1 - 6.5e-05 23.0 1.1 0.087 13.0 0.4 3.1 2 1 1 3 3 3 1 B-block binding subunit of TFIIIC HTH_27 PF13463.6 KKK44584.1 - 0.00014 22.3 0.1 0.0068 16.9 0.1 2.3 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 KKK44584.1 - 0.00042 20.2 0.1 0.025 14.4 0.1 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 KKK44584.1 - 0.0013 18.6 0.0 0.55 10.2 0.0 2.6 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 KKK44584.1 - 0.0015 18.3 0.0 0.068 13.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain PCI PF01399.27 KKK44584.1 - 0.002 18.6 1.5 4.2 7.9 0.0 3.1 3 0 0 3 3 3 1 PCI domain HTH_20 PF12840.7 KKK44584.1 - 0.014 15.4 0.0 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 KKK44584.1 - 0.015 15.1 0.0 0.087 12.6 0.0 2.1 2 0 0 2 2 2 0 LexA DNA binding domain HTH_40 PF14493.6 KKK44584.1 - 0.021 15.3 0.0 0.067 13.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 KKK44584.1 - 0.024 15.0 0.2 0.61 10.5 0.1 2.5 2 0 0 2 2 2 0 Transcriptional regulator HTH_Tnp_ISL3 PF13542.6 KKK44584.1 - 0.024 14.0 0.0 0.34 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_DeoR PF08220.12 KKK44584.1 - 0.038 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_IclR PF09339.10 KKK44584.1 - 0.046 13.5 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_45 PF14947.6 KKK44584.1 - 0.048 13.7 0.3 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix mCpol PF18182.1 KKK44584.1 - 0.057 13.7 0.6 6.4 7.1 0.1 2.8 2 0 0 2 2 2 0 minimal CRISPR polymerase domain GntR PF00392.21 KKK44584.1 - 0.06 13.0 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 1 0 Bacterial regulatory proteins, gntR family Mga PF05043.13 KKK44584.1 - 0.066 13.8 0.9 12 6.6 0.0 2.7 3 0 0 3 3 2 0 Mga helix-turn-helix domain Phage_rep_O PF04492.13 KKK44584.1 - 0.071 13.7 0.2 1.3 9.7 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage replication protein O Mrx7 PF10906.8 KKK44584.1 - 0.078 13.2 0.1 12 6.2 0.0 2.8 2 0 0 2 2 2 0 MIOREX complex component 7 Trp_repressor PF01371.19 KKK44584.1 - 0.12 12.5 0.2 2.3 8.4 0.1 2.4 2 0 0 2 2 2 0 Trp repressor protein Fe_dep_repress PF01325.19 KKK44584.1 - 0.12 12.6 0.4 0.29 11.4 0.0 1.7 2 0 0 2 2 1 0 Iron dependent repressor, N-terminal DNA binding domain RP-C PF03428.13 KKK44584.1 - 0.13 11.9 0.1 0.75 9.4 0.0 2.1 3 0 0 3 3 2 0 Replication protein C N-terminal domain Sigma70_r4_2 PF08281.12 KKK44584.1 - 0.13 12.0 0.1 12 5.7 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 FeoC PF09012.10 KKK44584.1 - 0.15 12.1 0.1 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_29 PF13551.6 KKK44584.1 - 0.2 11.7 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_24 PF13412.6 KKK44585.1 - 2.2e-15 56.0 1.4 8.9e-07 28.4 0.1 2.9 3 0 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK44585.1 - 2.3e-14 52.9 0.0 6.5e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_11 PF08279.12 KKK44585.1 - 5e-07 29.6 0.1 0.0066 16.4 0.0 2.7 2 0 0 2 2 2 2 HTH domain HTH_Crp_2 PF13545.6 KKK44585.1 - 8.3e-06 25.7 0.0 0.039 13.9 0.0 2.3 2 0 0 2 2 2 2 Crp-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 KKK44585.1 - 1.8e-05 24.3 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_5 PF01022.20 KKK44585.1 - 4.2e-05 23.3 0.0 0.00051 19.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 KKK44585.1 - 4.3e-05 23.2 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_36 PF13730.6 KKK44585.1 - 5.9e-05 22.9 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain GntR PF00392.21 KKK44585.1 - 9.9e-05 21.9 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, gntR family HTH_Tnp_ISL3 PF13542.6 KKK44585.1 - 0.00013 21.3 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KKK44585.1 - 0.00018 21.2 0.0 0.049 13.4 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_20 PF12840.7 KKK44585.1 - 0.00035 20.6 0.0 0.52 10.4 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 KKK44585.1 - 0.00038 20.3 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_DeoR PF08220.12 KKK44585.1 - 0.00086 19.0 0.1 0.025 14.3 0.1 2.4 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain Dimerisation2 PF16864.5 KKK44585.1 - 0.0023 17.9 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain HTH_9 PF08221.11 KKK44585.1 - 0.0029 17.7 0.1 2.1 8.5 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_10 PF04967.12 KKK44585.1 - 0.0033 17.2 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 1 HTH DNA binding domain Mga PF05043.13 KKK44585.1 - 0.0044 17.6 0.2 5.5 7.7 0.0 2.4 2 0 0 2 2 2 1 Mga helix-turn-helix domain TFIIE_alpha PF02002.17 KKK44585.1 - 0.0065 16.3 0.6 0.59 10.0 0.2 2.5 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_28 PF13518.6 KKK44585.1 - 0.0096 16.0 0.0 0.74 10.0 0.0 2.7 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_40 PF14493.6 KKK44585.1 - 0.0099 16.3 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KKK44585.1 - 0.012 15.6 0.0 0.43 10.5 0.0 2.6 2 0 0 2 2 2 0 MarR family Spo0A_C PF08769.11 KKK44585.1 - 0.012 15.7 0.1 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal UPF0122 PF04297.14 KKK44585.1 - 0.015 15.5 0.1 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like PCI PF01399.27 KKK44585.1 - 0.019 15.4 0.1 0.94 10.0 0.0 2.6 3 0 0 3 3 2 0 PCI domain B-block_TFIIIC PF04182.12 KKK44585.1 - 0.024 14.8 0.0 0.07 13.3 0.0 1.7 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Rrf2 PF02082.20 KKK44585.1 - 0.043 14.2 0.0 7.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator HTH_38 PF13936.6 KKK44585.1 - 0.048 13.4 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Crp PF00325.20 KKK44585.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_7 PF02796.15 KKK44585.1 - 0.19 11.8 0.2 0.99 9.5 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase ABC_tran PF00005.27 KKK44586.1 - 1.9e-29 102.9 0.1 2.9e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KKK44586.1 - 1.5e-11 44.7 0.3 7.6e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKK44586.1 - 0.0016 18.3 0.1 0.22 11.2 0.3 2.2 1 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 KKK44586.1 - 0.0029 17.6 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 KKK44586.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain KdpD PF02702.17 KKK44586.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_23 PF13476.6 KKK44586.1 - 0.0092 16.5 3.9 0.031 14.8 3.9 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KKK44586.1 - 0.042 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KKK44586.1 - 0.072 12.8 0.5 4 7.1 0.3 2.5 2 1 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KKK44586.1 - 0.081 12.5 0.1 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KKK44586.1 - 0.12 11.8 0.1 7 6.0 0.1 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.24 KKK44587.1 - 3.5e-28 98.5 20.3 3.5e-28 98.5 20.3 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KKK44587.1 - 9.5e-16 57.8 26.7 9.5e-16 57.8 26.7 2.0 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KKK44587.1 - 2.9e-06 26.8 24.7 1.8e-05 24.2 24.7 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KKK44587.1 - 2.1e-05 24.6 12.8 2.1e-05 24.6 12.8 2.8 1 1 1 3 3 3 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 KKK44587.1 - 0.049 13.2 32.3 0.52 9.8 32.3 2.5 1 1 0 1 1 1 0 ABC-2 family transporter protein SP_C-Propep PF08999.10 KKK44587.1 - 3.5 7.5 7.6 1.1 9.1 0.8 2.5 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF389 PF04087.14 KKK44588.1 - 0.0003 20.8 1.0 0.00034 20.7 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF389) Spem1 PF15670.5 KKK44588.1 - 0.21 11.1 1.4 0.29 10.7 1.4 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 PhoU_div PF01865.16 KKK44590.1 - 9e-10 38.2 9.1 1e-09 38.0 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 DUF4047 PF13256.6 KKK44590.1 - 0.055 13.7 0.9 0.086 13.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) PhoU PF01895.19 KKK44590.1 - 0.16 12.5 5.6 0.21 12.1 4.0 2.0 1 1 1 2 2 2 0 PhoU domain BLI1 PF17324.2 KKK44590.1 - 1.9 9.2 11.1 16 6.2 6.4 3.0 2 1 0 2 2 2 0 BLOC-1 interactor 1 ATP-synt_C PF00137.21 KKK44591.1 - 8.9e-07 29.2 4.2 8.9e-07 29.2 4.2 2.1 2 0 0 2 2 2 1 ATP synthase subunit C 2TM PF13239.6 KKK44591.1 - 0.32 11.3 3.2 0.43 10.9 3.2 1.5 1 1 0 1 1 1 0 2TM domain GDC-P PF02347.16 KKK44594.1 - 1.5e-43 149.2 0.0 1.7e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KKK44594.1 - 0.00052 19.1 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 KKK44595.1 - 2.4e-11 43.1 0.0 5.9e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KKK44595.1 - 0.00019 20.5 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Helicase_C_2 PF13307.6 KKK44596.1 - 6.5e-35 120.8 0.0 4.9e-34 118.0 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 KKK44596.1 - 2.6e-31 108.6 0.8 4.7e-31 107.8 0.8 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KKK44596.1 - 7.7e-14 51.8 0.0 2.1e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Helical and beta-bridge domain ResIII PF04851.15 KKK44596.1 - 4.4e-08 33.3 0.1 1.9e-05 24.7 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK44596.1 - 0.00014 21.7 0.1 0.0073 16.1 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KKK44596.1 - 0.00033 20.2 0.2 0.019 14.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 KKK44596.1 - 0.00072 19.3 0.0 0.0045 16.7 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein zf-ribbon_3 PF13248.6 KKK44596.1 - 0.0028 17.0 0.5 0.0076 15.6 0.5 1.8 1 0 0 1 1 1 1 zinc-ribbon domain AAA PF00004.29 KKK44596.1 - 0.0091 16.4 0.0 3.5 8.0 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KKK44596.1 - 0.02 15.3 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_POL_M_15KD PF02150.16 KKK44596.1 - 0.021 14.7 3.6 0.054 13.4 3.6 1.8 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit AAA_22 PF13401.6 KKK44596.1 - 0.023 14.9 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK44596.1 - 0.032 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DZR PF12773.7 KKK44596.1 - 0.04 14.0 1.1 0.093 12.8 1.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon T2SSE PF00437.20 KKK44596.1 - 0.043 12.9 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein A2L_zn_ribbon PF08792.10 KKK44596.1 - 0.049 13.4 2.3 0.61 9.9 2.3 2.6 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF2075 PF09848.9 KKK44596.1 - 0.055 12.7 0.3 0.94 8.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) zinc-ribbons_6 PF07191.12 KKK44596.1 - 0.081 12.9 1.7 0.12 12.4 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbons Sigma54_activat PF00158.26 KKK44596.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RPA_interact_C PF14768.6 KKK44596.1 - 0.11 13.1 1.2 1.2 9.7 0.3 2.4 2 0 0 2 2 2 0 Replication protein A interacting C-terminal TniB PF05621.11 KKK44596.1 - 0.11 11.9 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Mg_chelatase PF01078.21 KKK44596.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TF_Zn_Ribbon PF08271.12 KKK44596.1 - 0.51 9.9 2.1 0.59 9.7 0.6 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding MFS_1 PF07690.16 KKK44597.1 - 4.2e-32 111.4 46.9 2.1e-18 66.4 13.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK44597.1 - 1.5e-08 33.9 39.7 3.5e-08 32.7 39.7 1.7 1 1 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.6 KKK44597.1 - 5.6e-06 25.2 11.7 5.6e-06 25.2 11.7 3.1 1 1 1 3 3 3 2 MFS/sugar transport protein FtsL PF04999.13 KKK44597.1 - 0.47 10.5 0.0 0.47 10.5 0.0 3.2 4 1 1 5 5 5 0 Cell division protein FtsL Glyco_transf_5 PF08323.11 KKK44598.1 - 2.5e-21 76.5 0.0 5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KKK44598.1 - 2.3e-20 72.9 0.0 6e-20 71.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK44598.1 - 2.3e-16 60.5 0.0 3.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKK44598.1 - 0.062 13.7 0.0 0.88 10.0 0.0 2.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 Ribonuc_L-PSP PF01042.21 KKK44599.1 - 4.9e-31 107.3 0.1 5.4e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_M20 PF01546.28 KKK44600.1 - 9.5e-27 94.0 0.0 1.4e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK44600.1 - 6.5e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK44600.1 - 1.2e-06 28.4 0.1 1.9e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 Peptidase family M28 Lipase_GDSL_3 PF14606.6 KKK44600.1 - 0.0048 17.1 0.4 0.009 16.2 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M42 PF05343.14 KKK44600.1 - 0.029 13.4 0.3 1.5 7.7 0.0 2.7 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase Peptidase_C69 PF03577.15 KKK44601.1 - 6e-08 32.0 0.1 1.7e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 KKK44601.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 1 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Ribosomal_L35Ae PF01247.18 KKK44602.1 - 3.1e-14 52.9 0.5 3.9e-14 52.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KKK44602.1 - 0.0011 19.1 0.1 0.79 10.0 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Ntox35 PF15534.6 KKK44602.1 - 0.051 14.0 0.4 0.076 13.5 0.4 1.4 1 1 0 1 1 1 0 Bacterial toxin 35 zf-B_box PF00643.24 KKK44603.1 - 0.021 15.0 13.8 0.021 15.0 13.8 3.4 2 1 1 3 3 3 0 B-box zinc finger Vps23_core PF09454.10 KKK44603.1 - 0.045 13.7 1.1 0.1 12.6 1.1 1.7 1 0 0 1 1 1 0 Vps23 core domain CdvA PF18822.1 KKK44603.1 - 0.11 12.3 9.2 0.14 12.0 7.0 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DASH_Ask1 PF08655.10 KKK44603.1 - 0.23 11.4 2.2 9.8 6.1 0.2 2.9 2 0 0 2 2 2 0 DASH complex subunit Ask1 TPR_MLP1_2 PF07926.12 KKK44603.1 - 0.28 11.3 4.4 0.74 9.9 4.4 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DZR PF12773.7 KKK44603.1 - 0.8 9.8 24.8 0.027 14.5 11.7 2.6 2 0 0 2 2 2 0 Double zinc ribbon FapA PF03961.13 KKK44603.1 - 5.9 5.4 10.8 16 4.0 0.2 2.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Meth_synt_2 PF01717.18 KKK44604.1 - 1e-05 25.0 0.0 3.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KKK44604.1 - 9.2e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain Snf7 PF03357.21 KKK44605.1 - 4.1e-09 36.3 1.2 4.1e-09 36.3 1.2 2.1 2 0 0 2 2 2 1 Snf7 Rx_N PF18052.1 KKK44605.1 - 0.27 11.5 3.3 2.1 8.6 0.5 3.0 3 0 0 3 3 3 0 Rx N-terminal domain Tup_N PF08581.10 KKK44605.1 - 0.45 10.9 6.4 0.58 10.5 0.8 3.1 3 0 0 3 3 3 0 Tup N-terminal TPX2 PF06886.11 KKK44605.1 - 2.3 8.5 12.0 0.15 12.4 3.9 2.7 2 1 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) cwf21 PF08312.12 KKK44605.1 - 4.1 7.6 10.6 0.21 11.8 4.4 2.1 2 0 0 2 2 2 0 cwf21 domain Fib_alpha PF08702.10 KKK44605.1 - 6.1 7.0 9.1 3.9 7.7 3.0 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DHQS PF01959.16 KKK44606.1 - 3.2e-107 358.5 2.5 3.6e-107 358.3 2.5 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase II Hint PF01079.20 KKK44606.1 - 0.059 12.9 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Hint module Glyco_hydro_57 PF03065.15 KKK44608.1 - 2e-33 116.0 1.0 2e-33 116.0 1.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 KKK44608.1 - 0.00083 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_38N PF01074.22 KKK44608.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain CPBP PF02517.16 KKK44610.1 - 1.5e-07 31.7 7.8 1.5e-07 31.7 7.8 1.9 2 1 0 2 2 1 1 CPBP intramembrane metalloprotease DZR PF12773.7 KKK44610.1 - 0.00024 21.0 7.5 0.013 15.6 7.5 2.4 1 1 0 1 1 1 1 Double zinc ribbon Mid2 PF04478.12 KKK44610.1 - 0.0013 18.6 0.9 0.0033 17.3 0.9 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor zinc-ribbons_6 PF07191.12 KKK44610.1 - 0.0041 17.1 5.3 0.51 10.4 0.5 2.2 1 1 1 2 2 2 2 zinc-ribbons zf-C3HC4_3 PF13920.6 KKK44610.1 - 0.021 14.7 6.9 1.1 9.1 1.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DNA_ligase_ZBD PF03119.16 KKK44610.1 - 0.027 14.5 0.8 3.3 7.8 0.0 2.6 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain AhpC-TSA PF00578.21 KKK44610.1 - 0.05 13.5 0.1 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family zinc_ribbon_15 PF17032.5 KKK44610.1 - 0.066 14.0 3.0 0.066 14.0 3.0 2.9 3 0 0 3 3 2 0 zinc-ribbon family BIR PF00653.21 KKK44610.1 - 0.17 12.5 3.1 17 6.2 0.7 2.8 2 1 0 2 2 2 0 Inhibitor of Apoptosis domain HypA PF01155.19 KKK44610.1 - 0.18 11.8 8.5 1.9 8.6 1.1 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KKK44610.1 - 0.22 11.3 17.4 0.045 13.5 6.0 3.4 2 1 1 3 3 3 0 zinc-ribbon domain Prok-RING_4 PF14447.6 KKK44610.1 - 0.56 10.1 5.9 0.35 10.8 0.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF678 PF05077.12 KKK44610.1 - 0.57 10.3 4.0 11 6.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF678) C1_1 PF00130.22 KKK44610.1 - 0.68 9.9 7.2 11 5.9 1.3 3.0 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KKK44610.1 - 0.81 9.9 6.6 12 6.1 0.5 3.0 2 1 1 3 3 3 0 Zinc ribbon domain zf-IS66 PF13005.7 KKK44610.1 - 0.93 9.9 7.4 31 5.1 0.0 3.2 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 zf-ribbon_3 PF13248.6 KKK44610.1 - 1.4 8.4 16.7 0.51 9.8 4.4 3.4 2 2 0 2 2 2 0 zinc-ribbon domain C1_2 PF03107.16 KKK44610.1 - 1.4 9.2 7.0 1.5 9.2 0.4 2.4 2 0 0 2 2 2 0 C1 domain YwiC PF14256.6 KKK44610.1 - 1.5 9.1 7.4 0.43 10.9 3.8 1.9 2 1 0 2 2 2 0 YwiC-like protein zf-NADH-PPase PF09297.11 KKK44610.1 - 2.7 7.7 4.6 40 4.0 0.0 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Mut7-C PF01927.16 KKK44610.1 - 2.8 8.1 4.6 24 5.0 0.1 2.5 1 1 1 2 2 2 0 Mut7-C RNAse domain NOB1_Zn_bind PF08772.11 KKK44610.1 - 3 8.1 7.5 23 5.2 0.2 2.7 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FYVE PF01363.21 KKK44610.1 - 3.7 7.7 5.7 2.4 8.4 1.8 2.1 1 1 1 2 2 2 0 FYVE zinc finger Zn_ribbon_17 PF17120.5 KKK44610.1 - 9.3 6.0 9.7 0.35 10.5 0.8 2.3 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type dNK PF01712.19 KKK44611.1 - 8.2e-12 45.4 2.0 1.7e-11 44.4 2.0 1.5 1 1 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 KKK44611.1 - 4.3e-09 36.3 0.6 6.9e-06 25.9 0.4 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_18 PF13238.6 KKK44611.1 - 5.8e-09 36.6 0.0 1.3e-08 35.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KKK44611.1 - 0.00096 19.3 0.3 0.003 17.7 0.2 1.9 2 0 0 2 2 2 1 Shikimate kinase AAA_17 PF13207.6 KKK44611.1 - 0.0022 18.4 0.1 0.49 10.8 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KKK44611.1 - 0.004 17.4 0.0 0.0095 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KKK44611.1 - 0.012 14.8 0.3 0.039 13.2 0.0 2.0 2 1 1 3 3 3 0 NB-ARC domain AAA_14 PF13173.6 KKK44611.1 - 0.021 14.9 3.6 0.41 10.7 0.0 2.6 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 KKK44611.1 - 0.023 15.2 0.2 0.098 13.2 0.2 2.0 1 1 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 KKK44611.1 - 0.027 13.7 0.0 0.064 12.5 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 KKK44611.1 - 0.036 14.5 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KKK44611.1 - 0.043 14.0 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain YqgF PF14639.6 KKK44611.1 - 0.055 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Robl_LC7 PF03259.17 KKK44612.1 - 0.0041 16.9 2.0 0.0073 16.1 0.5 1.9 2 0 0 2 2 2 1 Roadblock/LC7 domain MFS_2 PF13347.6 KKK44614.1 - 3.9e-16 58.6 23.5 5.2e-16 58.2 23.5 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KKK44614.1 - 3.8e-14 52.4 18.7 3.8e-14 52.4 18.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 KKK44614.1 - 6.7 7.0 8.5 4.8 7.5 2.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) THUMP PF02926.17 KKK44615.1 - 0.00081 19.5 0.4 0.00081 19.5 0.4 2.9 3 1 0 3 3 3 1 THUMP domain DnaJ_CXXCXGXG PF00684.19 KKK44615.1 - 0.13 12.7 3.4 0.17 12.3 0.9 2.4 3 0 0 3 3 3 0 DnaJ central domain Ribosomal_L21e PF01157.18 KKK44616.1 - 1.5e-28 98.6 5.9 1.7e-28 98.4 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_pol_Rpb4 PF03874.16 KKK44617.1 - 5.6e-06 26.7 4.2 1.1e-05 25.7 4.2 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF1836 PF08876.11 KKK44617.1 - 0.022 14.8 0.8 0.028 14.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) AAA_12 PF13087.6 KKK44617.1 - 0.045 13.4 0.7 0.048 13.3 0.7 1.1 1 0 0 1 1 1 0 AAA domain DUF655 PF04919.12 KKK44618.1 - 1.1e-43 149.2 1.5 1.4e-43 148.9 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.6 KKK44618.1 - 0.0047 17.2 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif T4BSS_DotI_IcmL PF11393.8 KKK44618.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component Moulting_cycle PF04870.16 KKK44619.1 - 0.0072 15.7 2.9 0.0081 15.5 2.9 1.0 1 0 0 1 1 1 1 Moulting cycle YafQ_toxin PF15738.5 KKK44619.1 - 0.019 15.3 0.4 0.024 15.0 0.4 1.1 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Reticulon PF02453.17 KKK44620.1 - 0.02 14.9 0.2 0.98 9.4 0.2 2.1 2 0 0 2 2 2 0 Reticulon S_4TM PF18159.1 KKK44620.1 - 0.032 13.5 0.7 0.032 13.5 0.7 1.5 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain LRR_8 PF13855.6 KKK44622.1 - 2.6e-09 36.7 15.0 8.8e-06 25.4 1.0 4.1 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 KKK44622.1 - 9.4e-06 25.9 12.8 0.0018 18.6 2.0 4.3 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) YdiH PF15930.5 KKK44622.1 - 1.1 9.5 4.8 21 5.3 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function CSD PF00313.22 KKK44623.1 - 1.1e-23 82.8 2.0 1.3e-23 82.6 2.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KKK44623.1 - 8.9e-05 22.1 0.7 0.00057 19.5 0.7 2.0 1 1 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 KKK44623.1 - 0.12 12.3 0.2 0.23 11.4 0.1 1.5 1 1 0 1 1 1 0 Copper binding periplasmic protein CusF RrnaAD PF00398.20 KKK44624.1 - 2.1e-45 154.9 4.9 2.5e-45 154.6 4.9 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KKK44624.1 - 0.00088 19.9 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KKK44624.1 - 0.00098 18.9 0.8 0.0016 18.2 0.1 1.7 2 0 0 2 2 2 1 Met-10+ like-protein DREV PF05219.12 KKK44624.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase PPS_PS PF02006.16 KKK44624.1 - 0.026 14.1 0.9 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Phosphopantothenate/pantothenate synthetase Methyltransf_12 PF08242.12 KKK44624.1 - 0.026 15.3 0.0 0.07 13.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KKK44624.1 - 0.039 14.6 0.0 0.071 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KKK44624.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Autophagy_C PF10381.9 KKK44624.1 - 0.083 12.4 2.1 0.095 12.2 0.5 1.9 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal MTS PF05175.14 KKK44625.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KKK44625.1 - 1.3e-08 34.8 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK44625.1 - 1.7e-06 27.7 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KKK44625.1 - 8.6e-06 26.4 0.0 2.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KKK44625.1 - 2.6e-05 24.0 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KKK44625.1 - 0.00019 21.4 0.0 0.0026 17.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK44625.1 - 0.0021 18.7 0.0 0.0049 17.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KKK44625.1 - 0.0051 16.4 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase rRNA_methylase PF06962.12 KKK44625.1 - 0.02 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative rRNA methylase Methyltransf_23 PF13489.6 KKK44625.1 - 0.032 14.1 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KKK44625.1 - 0.06 13.1 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pom PF17251.2 KKK44625.1 - 0.063 12.6 0.1 0.088 12.1 0.1 1.3 1 0 0 1 1 1 0 Protochlamydia outer membrane protein Methyltransf_16 PF10294.9 KKK44625.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TRM PF02005.16 KKK44625.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Cons_hypoth95 PF03602.15 KKK44625.1 - 0.17 11.5 0.1 0.49 10.0 0.1 1.8 1 1 0 1 1 1 0 Conserved hypothetical protein 95 NurA PF09376.10 KKK44626.1 - 2.2e-17 63.6 2.8 3.6e-17 62.9 2.8 1.4 1 0 0 1 1 1 1 NurA domain DUF5124 PF17160.4 KKK44626.1 - 0.071 13.9 0.1 0.23 12.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5124) TDH PF03347.13 KKK44626.1 - 0.091 12.3 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin DUF362 PF04015.12 KKK44628.1 - 8.4e-32 111.1 0.2 1.1e-31 110.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF362) Fer4_21 PF14697.6 KKK44628.1 - 8.5e-06 25.8 9.7 1.8e-05 24.8 9.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44628.1 - 0.00043 20.0 10.4 0.12 12.2 0.2 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain RLI PF04068.15 KKK44628.1 - 0.00043 20.0 4.5 0.00059 19.6 0.3 2.4 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4_10 PF13237.6 KKK44628.1 - 0.00058 19.9 13.7 0.002 18.2 2.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44628.1 - 0.00072 19.5 11.7 0.013 15.6 1.9 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK44628.1 - 0.00089 19.8 11.9 0.0078 16.8 12.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44628.1 - 0.00092 20.1 10.6 0.047 14.6 1.2 2.6 1 1 2 3 3 3 3 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK44628.1 - 0.0019 18.3 11.2 0.0038 17.4 11.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lar_N PF09861.9 KKK44628.1 - 0.0057 15.8 1.7 0.0091 15.2 1.7 1.4 1 0 0 1 1 1 1 Lactate racemase N-terminal domain Fer4_15 PF13459.6 KKK44628.1 - 0.019 15.7 0.3 3.7 8.4 0.0 2.9 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_2 PF12797.7 KKK44628.1 - 0.6 10.3 12.6 4.8 7.5 2.7 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK44628.1 - 0.91 10.1 9.0 1.9 9.1 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 KKK44628.1 - 1.1 10.0 12.1 4.7 8.0 0.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Acetyltransf_1 PF00583.25 KKK44630.1 - 0.00055 20.2 0.0 0.0018 18.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3850 PF12961.7 KKK44632.1 - 0.0045 17.0 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3850) Sulfatase PF00884.23 KKK44633.1 - 1e-43 149.9 0.2 1.3e-43 149.6 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK44633.1 - 1.4e-05 24.9 0.0 0.00027 20.6 0.0 2.3 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KKK44633.1 - 0.0023 18.2 0.6 0.023 14.9 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KKK44633.1 - 0.007 15.0 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) AMP-binding PF00501.28 KKK44634.1 - 1.8e-61 208.0 0.0 2.1e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK44634.1 - 7.1e-08 33.3 0.0 1.5e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polyketide_cyc2 PF10604.9 KKK44635.1 - 0.00073 19.8 0.0 0.00088 19.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AMP-binding PF00501.28 KKK44636.1 - 8.9e-62 209.0 0.0 1.1e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK44636.1 - 1.7e-09 38.5 0.0 3e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UPF0147 PF03685.13 KKK44641.1 - 2.2 8.4 5.8 1.6 8.8 0.3 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) Elf1 PF05129.13 KKK44642.1 - 5.9e-19 67.9 1.0 5.9e-19 67.9 1.0 1.7 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 KKK44642.1 - 0.00071 19.6 0.7 1.2 9.3 0.0 2.4 2 0 0 2 2 2 2 Zinc ribbon domain Lar_restr_allev PF14354.6 KKK44642.1 - 0.0042 17.4 0.6 0.0083 16.5 0.6 1.5 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-ISL3 PF14690.6 KKK44642.1 - 0.0086 16.7 0.8 1.2 9.9 0.2 2.6 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.6 KKK44642.1 - 0.012 14.9 1.4 0.97 8.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KKK44642.1 - 0.021 14.8 0.8 0.053 13.5 0.8 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain HypA PF01155.19 KKK44642.1 - 0.03 14.3 1.0 0.08 13.0 1.0 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA tRNA-synt_1f PF01921.18 KKK44642.1 - 0.052 12.5 0.9 0.08 11.9 0.6 1.4 1 1 0 1 1 1 0 tRNA synthetases class I (K) DZR PF12773.7 KKK44642.1 - 0.07 13.2 0.6 0.13 12.3 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon eIF-5_eIF-2B PF01873.17 KKK44642.1 - 0.078 12.9 0.5 0.16 11.8 0.5 1.6 1 0 0 1 1 1 0 Domain found in IF2B/IF5 zf-RING_7 PF02591.15 KKK44642.1 - 0.095 12.9 1.2 0.63 10.3 0.1 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain Ribosomal_L32p PF01783.23 KKK44642.1 - 0.097 12.9 4.1 4.4 7.6 0.5 2.5 1 1 1 2 2 2 0 Ribosomal L32p protein family zinc_ribbon_5 PF13719.6 KKK44642.1 - 0.099 12.4 3.6 0.32 10.8 3.6 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 KKK44642.1 - 0.11 12.4 0.2 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG zinc_ribbon_4 PF13717.6 KKK44642.1 - 0.13 12.2 5.1 0.32 11.0 3.9 2.3 2 1 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 KKK44642.1 - 0.18 12.3 0.6 0.18 12.3 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger double domain CpXC PF14353.6 KKK44642.1 - 0.23 11.5 2.8 5.1 7.2 0.1 2.4 1 1 1 2 2 2 0 CpXC protein OrfB_Zn_ribbon PF07282.11 KKK44642.1 - 0.24 11.3 2.8 0.74 9.8 2.8 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain HalOD2 PF18547.1 KKK44642.1 - 1 9.3 2.8 6.2 6.8 2.9 2.0 1 1 0 1 1 1 0 Halobacterial output domain 2 zinc_ribbon_2 PF13240.6 KKK44642.1 - 2.3 8.0 6.5 5.8 6.8 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain FdhE PF04216.12 KKK44642.1 - 3.3 7.5 4.6 33 4.2 0.1 2.6 2 1 1 3 3 3 0 Protein involved in formate dehydrogenase formation YabA PF06156.13 KKK44642.1 - 7.5 7.3 8.2 9.8 6.9 3.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA TF_Zn_Ribbon PF08271.12 KKK44642.1 - 7.7 6.1 9.2 14 5.3 5.3 2.8 2 1 1 3 3 3 0 TFIIB zinc-binding HGD-D PF06050.13 KKK44648.1 - 6.9e-23 81.9 0.0 9.9e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component GAS PF13851.6 KKK44648.1 - 0.22 10.8 0.5 0.51 9.6 0.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lactamase_B_2 PF12706.7 KKK44650.1 - 0.0002 20.9 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK44650.1 - 0.00026 21.0 0.1 0.0003 20.8 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 KKK44651.1 - 3e-45 154.7 75.5 5.6e-34 117.6 38.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK44651.1 - 1e-10 41.1 37.3 1.4e-05 24.1 15.5 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 KKK44651.1 - 0.00053 18.5 16.6 0.00072 18.1 16.6 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KKK44651.1 - 0.0063 14.9 2.1 0.0063 14.9 2.1 2.8 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KKK44651.1 - 0.055 12.3 27.8 0.021 13.7 10.2 2.8 1 1 2 3 3 3 0 MFS_1 like family Cupin_2 PF07883.11 KKK44653.1 - 2.8e-08 33.4 0.0 3.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KKK44653.1 - 0.00015 21.6 0.0 0.0002 21.3 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Ectoine_synth PF06339.12 KKK44653.1 - 0.0013 18.9 0.0 0.0016 18.6 0.0 1.2 1 1 0 1 1 1 1 Ectoine synthase EutQ PF06249.12 KKK44653.1 - 0.007 16.1 0.1 0.0071 16.1 0.1 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ MannoseP_isomer PF01050.18 KKK44653.1 - 0.051 13.5 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase CENP-C_C PF11699.8 KKK44653.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like Pirin_C PF05726.13 KKK44653.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Pirin C-terminal cupin domain DUF2695 PF10905.8 KKK44655.1 - 0.00012 22.2 0.1 0.00036 20.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2695) zf-piccolo PF05715.13 KKK44655.1 - 0.067 13.3 1.3 0.11 12.6 1.3 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger zf-C3HC4_3 PF13920.6 KKK44655.1 - 0.074 12.9 1.3 0.12 12.2 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1848 PF08902.11 KKK44656.1 - 2.2e-64 217.8 3.4 2.5e-64 217.6 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1848) Pox_L5 PF04872.13 KKK44656.1 - 0.063 13.2 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 Poxvirus L5 protein family Dynamitin PF04912.14 KKK44657.1 - 0.024 14.0 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 Dynamitin DUF5066 PF16728.5 KKK44657.1 - 0.05 12.9 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) NleF_casp_inhib PF16809.5 KKK44658.1 - 0.00084 19.3 4.2 0.0013 18.7 4.2 1.3 1 0 0 1 1 1 1 NleF caspase inhibitor bZIP_1 PF00170.21 KKK44658.1 - 0.009 16.1 4.1 0.009 16.1 4.1 2.3 2 0 0 2 2 2 1 bZIP transcription factor Cnn_1N PF07989.11 KKK44658.1 - 0.013 15.7 11.4 0.029 14.5 11.4 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 SpoVIF PF14069.6 KKK44658.1 - 0.019 14.7 2.9 0.019 14.7 2.9 2.2 2 1 0 2 2 2 0 Stage VI sporulation protein F Prok-RING_1 PF14446.6 KKK44658.1 - 0.024 14.5 1.8 0.074 13.0 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PknG_rubred PF16919.5 KKK44658.1 - 0.028 14.6 0.3 3.3 7.9 0.1 2.3 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain Spc24 PF08286.11 KKK44658.1 - 0.054 13.7 3.6 0.098 12.9 3.6 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 zinc_ribbon_5 PF13719.6 KKK44658.1 - 0.15 11.8 3.4 1.2 8.9 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KKK44658.1 - 0.19 11.4 3.1 4.1 7.1 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_4 PF13717.6 KKK44658.1 - 0.35 10.8 3.1 3.1 7.8 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK44658.1 - 0.84 9.1 5.2 2 8.0 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 KKK44658.1 - 0.88 9.6 5.1 2.5 8.1 5.0 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Shugoshin_N PF07558.11 KKK44658.1 - 1.2 9.0 6.3 1.3 8.9 0.2 2.9 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region TMPIT PF07851.13 KKK44658.1 - 1.4 8.1 5.4 1.9 7.6 5.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 KKK44658.1 - 1.8 8.4 9.3 17 5.3 8.1 2.5 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 KKK44658.1 - 3.4 6.7 10.8 0.36 9.9 6.1 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIS_C PF01096.18 KKK44658.1 - 3.6 7.5 5.8 34 4.4 1.8 2.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) ADK_lid PF05191.14 KKK44658.1 - 4.3 7.4 6.1 14 5.8 6.1 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid APG6_N PF17675.1 KKK44658.1 - 5.6 7.5 11.4 13 6.3 6.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Ribosomal_S27 PF01599.19 KKK44658.1 - 5.8 7.2 6.8 17 5.7 0.5 2.6 2 0 0 2 2 2 0 Ribosomal protein S27a Gelsolin PF00626.22 KKK44659.1 - 2e-06 27.6 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Gelsolin repeat NTP_transferase PF00483.23 KKK44662.1 - 1.4e-39 136.2 0.0 1.7e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KKK44662.1 - 1.5e-10 40.4 9.0 0.0022 17.6 1.0 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKK44662.1 - 1e-07 32.4 0.0 1.5e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KKK44662.1 - 3.3e-07 29.6 2.4 0.014 14.4 1.3 2.2 2 0 0 2 2 2 2 L-fucokinase DUF4954 PF16314.5 KKK44662.1 - 0.0027 15.9 3.1 0.004 15.3 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KKK44662.1 - 7 6.5 11.3 13 5.6 1.6 3.8 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4190 PF13828.6 KKK44663.1 - 5.6e-08 32.4 12.5 9.4e-08 31.7 12.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) zinc_ribbon_2 PF13240.6 KKK44663.1 - 6.7e-06 25.6 3.4 9.7e-06 25.1 3.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK44663.1 - 4.9e-05 22.6 2.8 7.6e-05 22.0 2.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK44663.1 - 0.00011 22.1 1.5 0.00015 21.7 1.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2207 PF09972.9 KKK44663.1 - 0.012 14.4 0.3 0.012 14.4 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zinc_ribbon_15 PF17032.5 KKK44663.1 - 0.02 15.6 3.5 0.028 15.2 3.5 1.2 1 0 0 1 1 1 0 zinc-ribbon family YhfH PF14149.6 KKK44663.1 - 0.034 14.1 4.6 3 7.9 1.3 2.3 1 1 1 2 2 2 0 YhfH-like protein zf-C3HC4_3 PF13920.6 KKK44663.1 - 0.067 13.1 1.4 0.085 12.7 1.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 KKK44663.1 - 0.15 12.1 1.0 0.23 11.5 1.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 KKK44663.1 - 0.21 11.1 2.2 2.3 7.8 2.2 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 KKK44663.1 - 0.26 11.2 1.7 16 5.5 0.1 2.2 1 1 1 2 2 2 0 Nudix N-terminal DUF3040 PF11239.8 KKK44663.1 - 0.31 11.3 4.8 0.17 12.2 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1610 PF07754.11 KKK44663.1 - 0.35 10.9 5.5 2.9 7.9 5.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1610) zf-C2HC5 PF06221.13 KKK44663.1 - 0.99 9.4 3.7 6.7 6.8 3.9 1.9 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Sgf11 PF08209.11 KKK44663.1 - 1.1 8.9 4.9 9.7 5.9 0.6 2.2 1 1 1 2 2 2 0 Sgf11 (transcriptional regulation protein) PelG PF16933.5 KKK44664.1 - 0.00055 18.9 4.7 0.00067 18.6 4.7 1.0 1 0 0 1 1 1 1 Putative exopolysaccharide Exporter (EPS-E) DUF1516 PF07457.11 KKK44664.1 - 0.12 12.6 2.9 0.23 11.7 2.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1516) APA3_viroporin PF11289.8 KKK44664.1 - 0.55 9.7 2.8 0.69 9.4 2.8 1.1 1 0 0 1 1 1 0 Coronavirus accessory protein 3a Metallophos_2 PF12850.7 KKK44665.1 - 2e-19 70.4 0.0 2.3e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KKK44665.1 - 9.1e-08 32.8 3.2 0.0022 18.5 0.4 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_57 PF03065.15 KKK44666.1 - 2.1e-49 168.5 6.5 2.1e-49 168.5 6.5 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 57 DUF1957 PF09210.11 KKK44666.1 - 4.1e-22 78.5 0.4 4.1e-22 78.5 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1957) Usp PF00582.26 KKK44667.1 - 2.2e-20 73.6 0.0 8.3e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family Mur_ligase_M PF08245.12 KKK44667.1 - 0.08 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Mur ligase middle domain Usp PF00582.26 KKK44668.1 - 2.3e-17 63.8 0.0 4.6e-17 62.8 0.0 1.4 1 1 0 1 1 1 1 Universal stress protein family TrfA PF07042.11 KKK44669.1 - 0.041 12.9 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 TrfA protein Band_7 PF01145.25 KKK44670.1 - 2.3e-36 125.5 4.8 2.9e-36 125.1 4.8 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KKK44670.1 - 2.2e-06 27.5 1.4 3.7e-06 26.8 0.6 1.6 1 1 1 2 2 2 1 SPFH domain-Band 7 family Clathrin_H_link PF13838.6 KKK44670.1 - 0.041 13.8 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Clathrin-H-link DUF1957 PF09210.11 KKK44671.1 - 7.5e-25 87.3 0.1 1.1e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1957) CheB_methylest PF01339.17 KKK44677.1 - 2.4e-55 186.9 0.0 1.1e-54 184.7 0.0 2.0 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 KKK44677.1 - 8.4e-23 80.7 0.2 2.1e-21 76.2 0.3 2.4 2 0 0 2 2 2 1 Response regulator receiver domain EFG_C PF00679.24 KKK44678.1 - 9e-07 28.8 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus AsiA PF09010.10 KKK44678.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Anti-Sigma Factor A Molybdopterin PF00384.22 KKK44680.1 - 3.9e-73 246.9 0.0 5e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KKK44680.1 - 1e-26 93.1 0.0 9.3e-26 90.0 0.0 2.4 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 KKK44680.1 - 9.1e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4_11 PF13247.6 KKK44681.1 - 3.9e-25 87.9 9.4 3.9e-25 87.9 9.4 1.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK44681.1 - 8.1e-14 52.0 20.1 1.3e-08 35.3 4.2 3.6 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44681.1 - 2.2e-12 46.5 32.4 8.6e-05 22.4 1.8 4.9 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_10 PF13237.6 KKK44681.1 - 5.4e-11 42.4 24.5 0.00015 21.8 10.0 3.6 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK44681.1 - 8.5e-11 41.3 27.2 0.00091 19.2 2.5 4.4 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_9 PF13187.6 KKK44681.1 - 1.3e-10 41.3 22.8 4.5e-09 36.3 4.6 3.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44681.1 - 1.3e-10 40.6 32.3 0.00014 21.5 3.6 6.6 7 0 0 7 7 7 4 4Fe-4S binding domain Fer4_3 PF12798.7 KKK44681.1 - 6.7e-08 32.9 37.9 0.033 15.1 5.1 4.9 4 1 0 4 4 4 4 4Fe-4S binding domain Fer4_21 PF14697.6 KKK44681.1 - 1.4e-05 25.1 27.9 0.0008 19.5 0.8 4.0 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44681.1 - 0.00012 23.0 25.9 0.87 10.6 0.1 4.6 2 1 2 4 4 4 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK44681.1 - 0.00012 22.3 32.3 0.014 15.9 2.6 4.7 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_15 PF13459.6 KKK44681.1 - 0.0058 17.4 7.9 0.0058 17.4 7.9 4.6 2 2 1 3 3 3 1 4Fe-4S single cluster domain Fer4_17 PF13534.6 KKK44681.1 - 0.18 12.4 25.6 1.5e+02 3.0 1.5 4.5 1 1 1 2 2 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK44681.1 - 4.4 7.8 28.4 0.62 10.6 10.3 4.1 1 1 2 3 3 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 KKK44681.1 - 10 6.0 22.2 11 5.8 1.4 3.7 2 1 1 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster ADH_zinc_N PF00107.26 KKK44682.1 - 5.5e-22 78.1 0.0 1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK44682.1 - 2.8e-16 59.4 0.3 6.9e-16 58.1 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KKK44682.1 - 1.1e-06 28.4 0.4 2.2e-06 27.5 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KKK44682.1 - 2.6e-06 28.5 0.0 4.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KKK44682.1 - 0.00045 19.8 0.3 0.0061 16.1 0.3 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 KKK44682.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KKK44682.1 - 0.016 14.5 0.0 0.034 13.5 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_membrane_3 PF13748.6 KKK44682.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2-Hacid_dh_C PF02826.19 KKK44682.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KKK44683.1 - 2e-42 144.9 0.2 2.6e-42 144.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK44683.1 - 2.7e-35 122.0 0.0 3.6e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK44683.1 - 1.4e-07 31.6 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KKK44683.1 - 0.0013 18.6 0.2 0.0026 17.7 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KKK44683.1 - 0.07 13.4 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ubie_methyltran PF01209.18 KKK44683.1 - 0.13 11.5 0.2 0.2 10.9 0.2 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Lactamase_B PF00753.27 KKK44684.1 - 1.2e-26 94.0 0.0 1.8e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK44684.1 - 1e-06 28.4 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KKK44684.1 - 6.7e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK44684.1 - 0.0026 17.6 0.0 0.0081 16.1 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain DUF465 PF04325.13 KKK44685.1 - 0.0083 16.1 0.3 0.16 12.0 0.0 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF465) DUF5388 PF17363.2 KKK44685.1 - 0.036 14.3 0.6 0.078 13.2 0.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5388) Fer4_12 PF13353.6 KKK44685.1 - 0.14 12.5 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain PIN PF01850.21 KKK44686.1 - 7.2e-06 26.5 0.1 9.2e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 PIN domain Tobravirus_2B PF05271.11 KKK44686.1 - 0.012 15.6 0.5 0.018 14.9 0.4 1.3 1 1 0 1 1 1 0 Tobravirus 2B protein Lactamase_B_2 PF12706.7 KKK44687.1 - 1.6e-19 70.2 0.0 2.1e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK44687.1 - 1.3e-08 35.1 0.0 1.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 KKK44687.1 - 0.014 15.3 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ECH_1 PF00378.20 KKK44690.1 - 4.3e-45 154.0 0.0 4.9e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK44690.1 - 2.9e-18 66.5 0.0 4.6e-18 65.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Trigger_C PF05698.14 KKK44690.1 - 0.11 12.4 0.3 0.19 11.8 0.3 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus ECH_1 PF00378.20 KKK44691.1 - 4.3e-14 52.4 0.0 4.6e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK44691.1 - 1.1e-11 44.9 0.0 1.1e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1415 PF07209.12 KKK44691.1 - 0.1 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) Borrelia_lipo_1 PF05714.11 KKK44693.1 - 0.14 11.9 5.9 0.87 9.3 0.4 2.1 1 1 1 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein Flavodoxin_3 PF12641.7 KKK44696.1 - 5.5e-05 22.9 0.0 5.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.7 KKK44696.1 - 0.0083 16.4 0.0 0.009 16.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 KKK44696.1 - 0.03 14.6 0.0 0.034 14.4 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin Flavodoxin_4 PF12682.7 KKK44696.1 - 0.045 13.4 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin DUF2232 PF09991.9 KKK44697.1 - 0.0024 17.1 2.1 0.0024 17.1 2.1 2.1 1 1 1 2 2 2 1 Predicted membrane protein (DUF2232) FixS PF03597.15 KKK44697.1 - 0.078 12.7 0.5 0.078 12.7 0.5 4.5 4 2 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type DUF3367 PF11847.8 KKK44697.1 - 0.41 8.4 6.5 0.48 8.2 6.5 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Gaa1 PF04114.14 KKK44697.1 - 2.6 6.9 11.4 5.3 5.9 11.4 1.5 1 1 0 1 1 1 0 Gaa1-like, GPI transamidase component DHHC PF01529.20 KKK44697.1 - 5.4 7.1 19.0 3.8 7.6 4.6 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF2070 PF09843.9 KKK44697.1 - 6.7 4.9 27.8 7.1 4.8 27.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SPC25 PF06703.11 KKK44697.1 - 8.7 6.1 10.5 1.8 8.3 1.0 2.2 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) TssN PF17555.2 KKK44697.1 - 9.5 5.5 22.9 12 5.1 22.9 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Fer4_7 PF12838.7 KKK44698.1 - 1.3e-06 28.9 7.2 2.4e-06 28.0 7.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44698.1 - 8.3e-06 26.7 9.8 8.5e-05 23.4 9.8 2.4 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK44698.1 - 9.7e-06 25.6 6.2 0.0024 18.0 9.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK44698.1 - 0.00013 22.3 1.3 0.036 14.5 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44698.1 - 0.00073 19.2 13.4 0.0094 15.7 1.9 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK44698.1 - 0.0016 18.6 8.8 0.099 12.8 9.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK44698.1 - 0.0034 17.5 9.4 0.022 14.9 9.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Dehalogenase PF13486.6 KKK44698.1 - 0.0048 16.3 0.0 0.0061 16.0 0.0 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_17 PF13534.6 KKK44698.1 - 0.0057 17.2 3.6 0.71 10.5 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44698.1 - 0.026 14.6 11.8 0.72 10.0 2.6 2.5 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK44698.1 - 0.051 14.1 12.3 1.1 9.9 1.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Cytochrome_cB PF11783.8 KKK44698.1 - 0.075 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c bacterial Fer4_3 PF12798.7 KKK44698.1 - 0.11 13.5 11.4 1.2 10.2 3.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK44698.1 - 0.53 10.5 12.6 2.6 8.3 2.1 2.7 2 1 0 2 2 2 0 4Fe-4S binding domain HAD_2 PF13419.6 KKK44699.1 - 1.1e-23 84.2 0.8 1.4e-23 83.9 0.8 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK44699.1 - 4.6e-09 36.9 0.0 1.4e-05 25.5 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK44699.1 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 KKK44699.1 - 0.014 15.3 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase HAD PF12710.7 KKK44699.1 - 0.16 12.4 0.0 0.66 10.4 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ThiF PF00899.21 KKK44700.1 - 4.4e-56 190.0 0.0 9.4e-56 188.9 0.0 1.4 1 1 0 1 1 1 1 ThiF family MIT PF04212.18 KKK44701.1 - 1.1e-21 76.7 107.2 0.01 15.9 0.2 21.7 22 2 1 23 23 23 12 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KKK44701.1 - 2.2e-13 49.2 69.0 0.027 14.6 0.0 17.1 17 0 0 17 17 17 8 Tetratricopeptide repeat TPR_1 PF00515.28 KKK44701.1 - 2.1e-11 43.1 82.1 0.24 11.3 0.2 18.0 18 0 0 18 18 18 9 Tetratricopeptide repeat TPR_11 PF13414.6 KKK44701.1 - 3.1e-11 42.8 60.9 0.43 10.3 0.3 14.3 15 0 0 15 15 15 8 TPR repeat TPR_7 PF13176.6 KKK44701.1 - 3.7e-09 36.0 31.8 3 8.1 0.0 14.0 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_12 PF13424.6 KKK44701.1 - 1.9e-08 34.5 37.2 0.96 9.8 0.1 15.1 17 1 1 18 18 18 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 KKK44701.1 - 4.8e-08 32.3 16.5 0.0049 16.3 0.0 9.3 8 0 0 8 8 8 2 SHNi-TPR TPR_16 PF13432.6 KKK44701.1 - 1.7e-06 28.5 11.0 4.5 8.0 0.1 9.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK44701.1 - 6.5e-05 23.4 12.4 13 6.9 0.1 11.2 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK44701.1 - 0.021 15.3 17.0 17 6.0 0.1 9.6 10 0 0 10 10 10 0 Tetratricopeptide repeat RACo_C_ter PF14574.6 KKK44702.1 - 1.6e-94 315.8 3.1 2.5e-94 315.2 3.1 1.3 1 0 0 1 1 1 1 C-terminal domain of RACo the ASKHA domain Raco_middle PF17651.1 KKK44702.1 - 2e-55 186.9 0.5 2e-55 186.9 0.5 1.8 2 0 0 2 2 2 1 RACo middle region RACo_linker PF17650.1 KKK44702.1 - 2.4e-22 78.6 0.1 5.9e-22 77.3 0.0 1.8 2 0 0 2 2 2 1 RACo linker region Fer2 PF00111.27 KKK44702.1 - 4.2e-06 26.6 0.0 8.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ras PF00071.22 KKK44703.1 - 3.7e-47 159.9 0.1 4.2e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44703.1 - 5.2e-31 107.4 0.0 6.8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44703.1 - 2.3e-12 46.7 0.0 2.6e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK44703.1 - 2.3e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK44703.1 - 1.3e-05 25.2 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KKK44703.1 - 8.6e-05 22.4 0.0 0.0069 16.2 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KKK44703.1 - 0.0014 19.0 0.1 0.0017 18.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KKK44703.1 - 0.0028 17.2 0.0 0.0071 15.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KKK44703.1 - 0.011 15.7 0.1 0.018 15.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 KKK44703.1 - 0.014 14.8 0.0 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 KKK44703.1 - 0.015 14.9 0.0 0.73 9.3 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KKK44703.1 - 0.015 15.0 0.2 0.083 12.6 0.0 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KKK44703.1 - 0.038 13.4 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CPT PF07931.12 KKK44703.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 KKK44703.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KKK44703.1 - 0.067 12.5 0.0 0.79 8.9 0.0 2.0 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 KKK44703.1 - 0.072 13.0 0.0 11 5.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KKK44703.1 - 0.11 12.7 0.0 0.82 9.9 0.0 2.0 1 1 0 2 2 2 0 AAA domain AA_kinase PF00696.28 KKK44704.1 - 3e-35 122.0 0.0 5.2e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KKK44704.1 - 9.6e-10 38.1 8.1 6.2e-07 29.1 2.9 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KKK44704.1 - 2.4e-09 36.8 0.8 1.2e-08 34.6 0.1 2.3 2 0 0 2 2 2 1 ACT domain PHP PF02811.19 KKK44705.1 - 2.1e-09 37.9 0.6 3.8e-09 37.1 0.6 1.7 1 1 0 1 1 1 1 PHP domain Arf PF00025.21 KKK44706.1 - 9e-20 70.8 0.0 2.2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK44706.1 - 8.4e-16 58.3 0.2 2.5e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK44706.1 - 3.6e-13 49.4 0.0 8.5e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK44706.1 - 2e-06 27.3 1.3 1.5e-05 24.5 0.1 2.9 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK44706.1 - 2.2e-06 27.7 0.1 8.2e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KKK44706.1 - 0.0049 17.4 0.0 0.037 14.5 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 KKK44706.1 - 0.007 16.9 0.1 0.033 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKK44706.1 - 0.065 13.1 2.4 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase Poxvirus_B22R_N PF13169.6 KKK44707.1 - 0.05 14.1 0.1 0.13 12.7 0.1 1.7 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal Glycos_transf_1 PF00534.20 KKK44708.1 - 1.9e-15 56.8 0.2 4.2e-15 55.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Polysacc_synt PF01943.17 KKK44709.1 - 1.9e-39 135.7 61.7 9.3e-38 130.2 38.4 2.0 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 KKK44709.1 - 4.4e-10 39.3 30.8 4.4e-10 39.3 30.8 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 KKK44709.1 - 3e-05 24.1 9.0 3e-05 24.1 9.0 5.0 2 1 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Methyltransf_24 PF13578.6 KKK44710.1 - 0.00088 20.3 0.0 0.0014 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KKK44710.1 - 0.079 12.1 0.2 0.43 9.7 0.1 2.0 1 1 0 2 2 2 0 O-methyltransferase Glycos_transf_2 PF00535.26 KKK44711.1 - 1.8e-28 99.5 0.0 2.8e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KKK44711.1 - 1.6e-08 34.4 0.1 3.1e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 KKK44711.1 - 1.6e-05 24.9 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KKK44711.1 - 0.0085 16.6 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 APOBEC4 PF18775.1 KKK44711.1 - 0.057 13.6 0.2 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 APOBEC4 ATP-synt_F PF01990.17 KKK44711.1 - 0.094 13.1 1.2 0.26 11.6 1.2 1.8 1 1 0 1 1 1 0 ATP synthase (F/14-kDa) subunit SNAD4 PF18750.1 KKK44711.1 - 0.16 12.1 0.1 3 8.0 0.0 2.2 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Glycos_transf_1 PF00534.20 KKK44712.1 - 1.9e-33 115.4 0.1 3.3e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK44712.1 - 4.3e-26 91.9 0.0 1.1e-25 90.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKK44712.1 - 5.6e-08 33.1 0.0 1.5e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Collectrin PF16959.5 KKK44712.1 - 0.046 13.5 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 Renal amino acid transporter Glyco_trans_4_2 PF13477.6 KKK44712.1 - 0.057 13.5 0.3 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 KKK44712.1 - 0.084 12.9 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Phage_terminase PF10668.9 KKK44712.1 - 0.37 10.8 1.6 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Phage terminase small subunit Phosphodiest PF01663.22 KKK44713.1 - 8.5e-43 147.3 0.3 1e-42 147.0 0.3 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KKK44713.1 - 0.0089 15.4 0.3 0.04 13.3 0.1 1.9 1 1 1 2 2 2 1 Metalloenzyme superfamily Coatomer_b_Cpla PF14806.6 KKK44713.1 - 0.035 14.1 0.4 0.089 12.8 0.4 1.6 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Epimerase PF01370.21 KKK44714.1 - 1.6e-17 63.8 0.0 1.2e-16 61.0 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK44714.1 - 7e-14 52.0 0.0 1.7e-07 30.9 0.0 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK44714.1 - 0.0012 18.0 0.0 0.0051 15.9 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 KKK44714.1 - 0.15 11.4 0.0 0.59 9.5 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thioredoxin PF00085.20 KKK44715.1 - 4.7e-29 100.4 0.1 5.1e-29 100.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK44715.1 - 1.4e-06 28.6 0.0 7.7e-05 22.9 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KKK44715.1 - 6.6e-06 26.5 0.1 1.8e-05 25.2 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KKK44715.1 - 0.0015 18.7 0.0 0.0023 18.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 KKK44715.1 - 0.021 14.9 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DUF2950 PF11453.8 KKK44715.1 - 0.031 13.5 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) AhpC-TSA PF00578.21 KKK44715.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 KKK44715.1 - 0.13 11.9 0.0 0.33 10.7 0.0 1.6 1 1 1 2 2 2 0 Redoxin TMEM251 PF15190.6 KKK44716.1 - 0.0094 15.9 0.3 0.0094 15.9 0.3 3.6 4 1 1 5 5 5 1 Transmembrane protein 251 Epimerase PF01370.21 KKK44717.1 - 7.7e-61 205.6 0.0 9.2e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK44717.1 - 5.2e-60 203.6 0.0 8.3e-60 202.9 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KKK44717.1 - 2.6e-29 102.1 0.0 3.2e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KKK44717.1 - 7.7e-26 90.9 0.0 4.1e-25 88.5 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KKK44717.1 - 5e-13 48.8 0.0 1e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK44717.1 - 1.1e-12 47.6 0.1 7e-11 41.8 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KKK44717.1 - 5.3e-10 39.5 0.0 8.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KKK44717.1 - 3.4e-07 29.9 0.1 1.3e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KKK44717.1 - 0.00014 21.5 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 KKK44717.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 KKK44717.1 - 0.11 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Epimerase_2 PF02350.19 KKK44718.1 - 2.4e-104 348.9 0.0 2.7e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Methyltransf_23 PF13489.6 KKK44719.1 - 0.0099 15.7 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK44719.1 - 0.025 15.2 0.0 0.091 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 KKK44719.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UQ_con PF00179.26 KKK44720.1 - 1e-05 25.2 11.5 0.006 16.2 0.0 4.3 3 2 1 4 4 4 3 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK44720.1 - 0.012 15.9 0.7 0.012 15.9 0.7 4.2 2 2 2 4 4 4 0 RWD domain Amidase PF01425.21 KKK44725.1 - 4.3e-33 115.0 0.0 6.8e-33 114.3 0.0 1.3 1 1 0 1 1 1 1 Amidase YokU PF14122.6 KKK44725.1 - 0.046 13.7 0.2 0.075 13.0 0.2 1.3 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin CO_dh PF02552.16 KKK44726.1 - 7.6e-25 87.6 0.0 1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit ACP_syn_III PF08545.10 KKK44726.1 - 0.16 11.9 0.1 0.42 10.5 0.0 1.7 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CdhC PF03598.15 KKK44727.1 - 1.3e-56 190.7 0.3 1.6e-56 190.5 0.3 1.0 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit Hydrolase_4 PF12146.8 KKK44730.1 - 0.00017 21.0 0.0 0.0046 16.3 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK44730.1 - 0.004 16.8 0.3 0.18 11.5 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Sds3 PF08598.11 KKK44731.1 - 0.0024 17.9 1.3 0.0029 17.6 1.3 1.3 1 1 0 1 1 1 1 Sds3-like DDE_Tnp_1 PF01609.21 KKK44731.1 - 0.0039 16.9 0.2 0.0076 15.9 0.2 1.5 1 1 0 1 1 1 1 Transposase DDE domain APH PF01636.23 KKK44734.1 - 4.5e-09 36.6 0.0 6.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KKK44734.1 - 5.4e-05 22.6 0.1 0.00011 21.6 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 KKK44734.1 - 0.0046 16.2 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.22 KKK44734.1 - 0.0075 15.9 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KKK44734.1 - 0.019 14.5 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase AHSP PF09236.10 KKK44734.1 - 0.038 14.4 0.1 1.9 9.0 0.1 2.5 2 1 0 2 2 2 0 Alpha-haemoglobin stabilising protein TadZ_N PF16968.5 KKK44735.1 - 0.17 11.6 0.0 0.45 10.2 0.0 1.6 1 1 0 1 1 1 0 Pilus assembly protein TadZ N-terminal NUDIX PF00293.28 KKK44736.1 - 0.0029 17.6 0.1 0.64 10.1 0.1 2.7 2 1 0 2 2 2 2 NUDIX domain Lactamase_B PF00753.27 KKK44737.1 - 4.6e-23 82.3 0.0 1.2e-22 80.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK44737.1 - 1.6e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KKK44737.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain DUF4909 PF16253.5 KKK44737.1 - 0.048 13.5 0.8 0.16 11.8 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4909) Lactamase_B_3 PF13483.6 KKK44737.1 - 0.091 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain AMP-binding PF00501.28 KKK44738.1 - 2.2e-56 191.3 0.0 2.7e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK44738.1 - 1.4e-05 25.9 0.0 2.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Myc-LZ PF02344.15 KKK44739.1 - 0.021 14.9 0.2 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain CdvA PF18822.1 KKK44739.1 - 0.023 14.5 1.1 0.023 14.5 1.1 4.8 4 1 1 5 5 5 0 CdvA-like coiled-coil domain FlgN PF05130.12 KKK44739.1 - 0.15 12.5 3.1 1.3 9.5 0.0 2.9 3 0 0 3 3 3 0 FlgN protein Dna2 PF08696.11 KKK44739.1 - 1.2 8.8 7.1 0.23 11.2 1.2 2.8 2 1 1 3 3 3 0 DNA replication factor Dna2 DUF5137 PF17220.3 KKK44739.1 - 7.3 7.5 8.5 95 4.0 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF5137) NAD_synthase PF02540.17 KKK44740.1 - 0.0015 17.7 0.5 0.0017 17.5 0.5 1.0 1 0 0 1 1 1 1 NAD synthase NAD_synthase PF02540.17 KKK44741.1 - 5.5e-41 140.3 0.1 6.5e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 KKK44741.1 - 5.1e-05 22.2 0.4 0.00015 20.6 0.4 1.7 1 1 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 KKK44741.1 - 0.033 13.9 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase QueC PF06508.13 KKK44741.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC N6_Mtase PF02384.16 KKK44744.1 - 4.6e-12 45.8 3.1 1.2e-10 41.2 3.1 2.5 1 1 0 1 1 1 1 N-6 DNA Methylase Eco57I PF07669.11 KKK44744.1 - 1.9e-11 44.4 1.4 4.3e-11 43.3 0.1 2.3 2 0 0 2 2 2 1 Eco57I restriction-modification methylase TaqI_C PF12950.7 KKK44744.1 - 1.2e-08 35.1 5.6 1.2e-08 35.1 5.6 2.9 3 0 0 3 3 3 1 TaqI-like C-terminal specificity domain UPF0020 PF01170.18 KKK44744.1 - 7e-06 25.9 0.0 2.8e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 KKK44744.1 - 0.05 13.4 0.6 0.24 11.2 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain VanZ PF04892.12 KKK44745.1 - 5.7e-15 56.1 11.0 2e-14 54.3 10.9 1.6 1 1 0 1 1 1 1 VanZ like family ATC_hydrolase PF14196.6 KKK44746.1 - 1.1e-09 39.2 0.1 1.4e-09 38.9 0.1 1.1 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase MetOD1 PF18546.1 KKK44746.1 - 2.7e-05 24.2 2.1 3.3e-05 23.9 1.4 1.5 1 1 0 1 1 1 1 Metanogen output domain 1 Amidohydro_2 PF04909.14 KKK44747.1 - 2.7e-27 96.3 0.1 3.5e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KKK44747.1 - 0.04 13.2 0.0 0.15 11.4 0.0 1.8 1 1 0 1 1 1 0 Amidohydrolase family PemK_toxin PF02452.17 KKK44750.1 - 0.084 13.3 0.0 0.087 13.2 0.0 1.0 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF1768 PF08719.11 KKK44752.1 - 1.4e-16 61.2 0.5 1.5e-16 61.0 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Glycos_transf_1 PF00534.20 KKK44753.1 - 1.1e-22 80.4 2.0 1.8e-22 79.7 2.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK44753.1 - 9.6e-22 77.8 0.0 1.4e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KKK44753.1 - 3.6e-10 40.0 0.7 9.5e-10 38.6 0.7 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 KKK44753.1 - 1.5e-09 38.1 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KKK44753.1 - 6.6e-05 23.4 0.0 0.00012 22.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_20 PF00982.21 KKK44753.1 - 0.015 14.0 0.7 0.51 8.9 0.0 2.4 1 1 1 2 2 2 0 Glycosyltransferase family 20 ESCRT-II PF05871.12 KKK44753.1 - 0.069 13.4 1.3 0.31 11.3 0.6 2.2 2 0 0 2 2 2 0 ESCRT-II complex subunit Glycos_transf_1 PF00534.20 KKK44754.1 - 9.1e-35 119.7 0.2 1.9e-34 118.7 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK44754.1 - 2.3e-26 92.8 0.0 3.8e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KKK44754.1 - 7.4e-10 39.1 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK44754.1 - 5.8e-05 23.2 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 KKK44754.1 - 0.01 15.9 0.3 0.026 14.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like DUF3880 PF12996.7 KKK44754.1 - 0.019 15.0 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) Methyltransf_23 PF13489.6 KKK44755.1 - 3.7e-12 46.4 0.0 5.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK44755.1 - 7.4e-10 38.8 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK44755.1 - 4.1e-09 37.1 0.0 6.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK44755.1 - 1.1e-08 34.8 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KKK44755.1 - 3.7e-08 34.0 0.0 6.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK44755.1 - 1.2e-07 32.2 0.0 2.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK44755.1 - 1.6e-06 27.3 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KKK44755.1 - 0.00037 20.1 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KKK44755.1 - 0.0042 17.2 0.0 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.17 KKK44755.1 - 0.061 12.5 0.0 0.54 9.4 0.0 1.9 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 KKK44755.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glycos_transf_1 PF00534.20 KKK44756.1 - 3.9e-18 65.6 0.0 1e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK44756.1 - 2.7e-14 53.7 0.0 5.9e-14 52.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK44756.1 - 2.7e-09 37.2 0.0 4.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 KKK44756.1 - 8.6e-07 29.1 1.4 2.5e-06 27.6 1.4 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KKK44756.1 - 0.01 16.2 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Asn_synthase PF00733.21 KKK44757.1 - 1.1e-86 291.8 0.0 1.3e-86 291.5 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 KKK44757.1 - 2.9e-47 159.6 0.0 5e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KKK44757.1 - 4.8e-38 130.4 0.0 8.3e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KKK44757.1 - 1.4e-07 31.2 0.1 4.3e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 Aluminium induced protein Cyt-b5 PF00173.28 KKK44757.1 - 0.02 15.1 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF1933 PF09147.10 KKK44757.1 - 0.079 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) NAD_synthase PF02540.17 KKK44757.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 NAD synthase DUF3552 PF12072.8 KKK44759.1 - 0.0004 19.9 16.9 0.00082 18.8 16.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF641 PF04859.12 KKK44759.1 - 0.0032 17.8 5.2 0.0032 17.8 5.2 2.3 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KKK44759.1 - 0.19 10.6 14.1 0.28 10.0 14.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KKK44759.1 - 0.34 10.8 35.2 0.054 13.4 16.1 4.7 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_23 PF13476.6 KKK44759.1 - 1.1 9.7 26.2 3.5 8.1 26.2 1.8 1 1 0 1 1 1 0 AAA domain Bac_luciferase PF00296.20 KKK44760.1 - 3.8e-12 46.3 0.0 4.2e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2887 PF11103.8 KKK44760.1 - 0.15 12.0 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) zf_C2H2_10 PF18414.1 KKK44762.1 - 9.9 5.8 7.5 33 4.1 1.5 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger DUF2383 PF09537.10 KKK44763.1 - 0.031 14.6 0.3 0.035 14.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Gtr1_RagA PF04670.12 KKK44766.1 - 1.3e-23 83.6 0.1 1.8e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK44766.1 - 2.8e-16 59.4 0.0 4.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK44766.1 - 7.1e-05 23.0 0.0 0.00019 21.6 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKK44766.1 - 7.7e-05 22.2 0.1 0.00076 19.0 0.0 2.3 2 2 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KKK44766.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KKK44766.1 - 0.0079 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PALP PF00291.25 KKK44767.1 - 1.2e-20 74.1 0.0 2.1e-20 73.3 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 KKK44767.1 - 4.2e-13 49.3 0.0 1.5e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus LDcluster4 PF18306.1 KKK44768.1 - 1.3e-27 96.3 0.1 1.4e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 SLOG cluster4 family Lysine_decarbox PF03641.14 KKK44768.1 - 0.00011 22.4 0.0 0.00037 20.6 0.0 1.8 1 1 0 1 1 1 1 Possible lysine decarboxylase DUF2375 PF09558.10 KKK44768.1 - 0.048 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Catalase_C PF18011.1 KKK44768.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases Homoserine_dh PF00742.19 KKK44769.1 - 1.6e-47 161.6 0.1 3.4e-47 160.6 0.1 1.5 1 1 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KKK44769.1 - 3.7e-05 24.4 0.0 0.00019 22.0 0.0 2.1 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF370 PF04025.12 KKK44770.1 - 0.0048 17.0 0.3 0.011 15.8 0.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF370) ACT_4 PF13291.6 KKK44770.1 - 0.018 15.6 5.9 0.44 11.2 0.0 3.0 1 1 2 3 3 3 0 ACT domain ACT PF01842.25 KKK44770.1 - 0.063 13.1 0.4 0.17 11.7 0.0 2.0 2 1 1 3 3 3 0 ACT domain AIRS_C PF02769.22 KKK44771.1 - 1.5e-12 47.9 0.0 2.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain SpoOE-like PF09388.10 KKK44771.1 - 0.047 13.6 0.1 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein EFG_C PF00679.24 KKK44774.1 - 1.6e-20 73.0 0.0 3.7e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KKK44774.1 - 4.4e-14 52.3 0.0 8.9e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KKK44774.1 - 3.8e-09 36.4 0.0 1.2e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KKK44774.1 - 0.00075 19.8 0.0 0.0041 17.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.22 KKK44775.1 - 3.5e-31 108.0 0.0 4e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK44775.1 - 1.3e-18 67.4 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK44775.1 - 7.8e-09 35.2 0.0 9.2e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KKK44775.1 - 1.9e-05 24.3 0.0 2.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain YdiH PF15930.5 KKK44776.1 - 0.08 13.1 0.5 0.23 11.7 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function N_formyltrans_C PF18216.1 KKK44776.1 - 0.43 10.3 6.1 0.41 10.4 1.0 2.5 2 0 0 2 2 2 0 N-formyltransferase dimerization C-terminal domain Iron_permease PF04120.12 KKK44776.1 - 2.3 8.0 9.8 0.34 10.7 2.2 2.3 1 1 1 2 2 2 0 Low affinity iron permease MMR_HSR1 PF01926.23 KKK44777.1 - 7.3e-12 45.4 0.1 1.1e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK44777.1 - 2.2e-07 30.5 0.4 7.8e-06 25.5 0.3 2.5 1 1 1 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK44777.1 - 5.3e-05 22.8 0.4 0.0023 17.5 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KKK44777.1 - 0.0013 18.7 1.8 0.14 12.0 0.2 2.5 2 1 0 2 2 2 2 RsgA GTPase Ras PF00071.22 KKK44777.1 - 0.0028 17.3 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KKK44777.1 - 0.0034 17.6 0.2 0.025 14.8 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKK44777.1 - 0.0059 16.1 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KKK44777.1 - 0.0072 16.6 0.1 0.018 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KKK44777.1 - 0.012 15.0 1.1 0.036 13.5 0.3 1.9 1 1 1 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KKK44777.1 - 0.048 14.2 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 KKK44777.1 - 0.42 11.0 2.8 6.1 7.3 2.8 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hydrolase PF00702.26 KKK44778.1 - 3.3e-07 30.8 0.0 4.3e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK44778.1 - 8.1e-06 26.4 0.0 1.6e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK44778.1 - 4.3e-05 23.4 1.6 0.00016 21.5 0.4 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KKK44778.1 - 0.0014 18.0 0.9 0.0047 16.4 0.9 1.8 1 1 0 1 1 1 1 Putative Phosphatase NT5C PF06941.12 KKK44778.1 - 0.0063 16.4 0.1 0.0094 15.8 0.1 1.3 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Coat_X PF07552.11 KKK44778.1 - 0.048 13.5 0.1 7.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Spore Coat Protein X and V domain Radical_SAM PF04055.21 KKK44779.1 - 1.4e-14 54.8 0.6 3.8e-09 37.1 0.0 2.6 1 1 1 2 2 2 2 Radical SAM superfamily Fer4_14 PF13394.6 KKK44779.1 - 0.03 14.4 0.1 9.1 6.5 0.0 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Rrf2 PF02082.20 KKK44779.1 - 0.048 14.0 0.1 0.099 13.0 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator Fer4_12 PF13353.6 KKK44779.1 - 0.048 13.9 0.0 0.85 9.9 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF4423 PF14394.6 KKK44779.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_45 PF14947.6 KKK44779.1 - 0.32 11.0 8.7 0.14 12.2 5.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix PNP_UDP_1 PF01048.20 KKK44780.1 - 7.5e-21 74.5 0.0 8.8e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HTH_24 PF13412.6 KKK44781.1 - 2.5e-11 42.9 1.4 2.1e-06 27.2 0.0 3.1 3 1 0 3 3 3 2 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 KKK44781.1 - 1.6e-05 24.9 0.0 0.017 15.2 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_11 PF08279.12 KKK44781.1 - 0.0019 18.1 1.2 0.2 11.7 0.0 3.0 3 0 0 3 3 3 1 HTH domain HTH_5 PF01022.20 KKK44781.1 - 0.013 15.4 0.1 0.039 13.8 0.0 1.9 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 KKK44781.1 - 0.056 13.8 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.7 KKK44781.1 - 0.078 12.9 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 MarR family Sigma70_r4 PF04545.16 KKK44781.1 - 0.087 12.4 0.7 2 8.0 0.0 3.1 3 0 0 3 3 3 0 Sigma-70, region 4 MarR PF01047.22 KKK44781.1 - 0.1 12.5 0.5 3.6 7.6 0.0 2.8 3 0 0 3 3 3 0 MarR family TyeA PF09059.10 KKK44782.1 - 0.023 14.8 0.2 2.8 8.1 0.1 2.5 1 1 1 2 2 2 0 TyeA DUF2214 PF09980.9 KKK44782.1 - 0.12 12.2 2.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2214) MgtE_N PF03448.17 KKK44782.1 - 0.34 11.5 4.8 2.4 8.8 2.9 2.8 1 1 1 2 2 2 0 MgtE intracellular N domain DUF1539 PF07560.11 KKK44782.1 - 0.7 10.0 5.0 1.3 9.1 1.9 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) DZR PF12773.7 KKK44783.1 - 0.001 19.0 0.5 0.0018 18.2 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK44783.1 - 0.0039 16.9 3.2 1.4 8.7 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain zf-C2H2_jaz PF12171.8 KKK44783.1 - 0.026 14.8 3.7 3.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding YhfH PF14149.6 KKK44783.1 - 0.032 14.2 0.5 5.8 7.0 0.0 2.3 2 0 0 2 2 2 0 YhfH-like protein zf-C2H2 PF00096.26 KKK44783.1 - 0.036 14.5 3.7 1.8 9.2 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.6 KKK44783.1 - 0.036 14.0 1.2 5.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal Zn_ribbon_recom PF13408.6 KKK44783.1 - 0.048 14.2 0.4 4.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DpnI PF06044.12 KKK44783.1 - 0.057 13.1 1.5 0.087 12.5 1.5 1.2 1 0 0 1 1 1 0 Dam-replacing family zf-C2H2_11 PF16622.5 KKK44783.1 - 0.091 12.5 2.2 0.18 11.6 0.3 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KKK44783.1 - 0.11 12.2 1.2 7.3 6.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 KKK44783.1 - 0.14 13.1 1.4 3.5 8.7 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KKK44783.1 - 0.15 12.2 2.6 0.94 9.6 2.7 2.0 1 1 1 2 2 2 0 Zinc ribbon domain Vps39_2 PF10367.9 KKK44783.1 - 0.17 12.3 1.0 0.32 11.5 1.0 1.4 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-ribbon_3 PF13248.6 KKK44783.1 - 0.22 11.0 1.8 1.7 8.1 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain XPA_N PF01286.18 KKK44783.1 - 0.33 11.0 5.3 1 9.4 0.2 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf-dskA_traR PF01258.17 KKK44783.1 - 0.42 10.6 2.4 11 6.0 0.2 2.3 1 1 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf-C2HE PF16278.5 KKK44783.1 - 1.3 9.5 5.2 2.5 8.6 0.7 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Abhydrolase_1 PF00561.20 KKK44784.1 - 2.5e-08 33.9 0.1 9.5e-06 25.4 0.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK44784.1 - 1.4e-07 31.0 0.0 0.00062 19.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 UPF0227 PF05728.12 KKK44784.1 - 2.9e-07 30.6 0.0 7.6e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 KKK44784.1 - 2.5e-06 27.5 0.1 0.00015 21.6 0.0 2.0 1 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 KKK44784.1 - 1.7e-05 24.6 0.0 2.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KKK44784.1 - 0.00044 20.0 0.0 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF5490 PF17593.2 KKK44784.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5490) Ser_hydrolase PF06821.13 KKK44784.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase Peptidase_S28 PF05577.12 KKK44784.1 - 0.21 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF2085 PF09858.9 KKK44785.1 - 1.9e-12 47.5 2.3 1.9e-12 47.5 2.3 3.6 2 2 2 4 4 4 1 Predicted membrane protein (DUF2085) UPF0203 PF05254.12 KKK44786.1 - 0.04 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF3958 PF13125.6 KKK44786.1 - 0.076 13.2 1.4 0.16 12.2 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) SMI1_KNR4 PF09346.10 KKK44788.1 - 0.0019 18.6 1.0 0.0029 18.0 1.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Neugrin PF06413.11 KKK44788.1 - 0.15 12.0 2.4 0.16 11.9 2.4 1.1 1 0 0 1 1 1 0 Neugrin GEMIN8 PF15348.6 KKK44788.1 - 0.22 11.8 4.0 0.25 11.6 4.0 1.0 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 TOBE PF03459.17 KKK44790.1 - 4.8e-06 26.8 0.0 4.9e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 TOBE domain TOBE_2 PF08402.10 KKK44790.1 - 0.0052 16.9 0.0 0.0054 16.9 0.0 1.0 1 0 0 1 1 1 1 TOBE domain SBBP PF06739.11 KKK44791.1 - 6.2e-21 74.1 45.8 1.1e-05 25.4 1.9 7.7 7 0 0 7 7 7 7 Beta-propeller repeat HAV_VP PF12944.7 KKK44791.1 - 0.0034 17.4 0.6 0.031 14.3 0.1 2.4 2 1 0 2 2 2 1 Hepatitis A virus viral protein VP Reg_prop PF07494.11 KKK44791.1 - 0.017 15.3 8.2 9.4 6.9 0.1 6.2 7 0 0 7 7 7 0 Two component regulator propeller Kelch_5 PF13854.6 KKK44791.1 - 0.55 10.3 7.5 35 4.5 0.1 4.7 5 0 0 5 5 5 0 Kelch motif ABC_tran PF00005.27 KKK44792.1 - 2.7e-31 108.9 0.3 6e-31 107.8 0.1 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KKK44792.1 - 2.4e-12 47.3 0.8 2.1e-05 24.5 0.2 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK44792.1 - 8.2e-12 45.0 3.1 3.8e-11 42.9 3.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TOBE PF03459.17 KKK44792.1 - 1.2e-10 41.5 0.0 2.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 TOBE domain TOBE_2 PF08402.10 KKK44792.1 - 2.9e-06 27.4 0.0 5.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 TOBE domain AAA_15 PF13175.6 KKK44792.1 - 4e-05 23.5 4.6 0.0048 16.6 0.4 2.4 1 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KKK44792.1 - 0.00038 21.0 5.8 0.00038 21.0 5.8 2.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KKK44792.1 - 0.0029 17.3 0.2 0.0067 16.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KKK44792.1 - 0.012 15.9 0.7 0.046 14.0 0.7 2.2 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKK44792.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KKK44792.1 - 0.032 13.9 1.8 0.2 11.4 1.5 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK44792.1 - 0.046 14.1 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KKK44792.1 - 0.075 13.3 0.0 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK44792.1 - 0.11 12.6 1.6 0.6 10.1 0.2 2.8 2 2 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KKK44792.1 - 0.13 12.8 0.1 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 KKK44793.1 - 3e-21 76.0 11.0 4.8e-21 75.3 11.0 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component NicO PF03824.16 KKK44793.1 - 0.22 10.8 6.7 0.2 11.0 2.9 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein Adeno_E3_CR2 PF02439.15 KKK44793.1 - 3.4 7.5 5.9 51 3.7 3.1 2.9 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 PBP_like_2 PF12849.7 KKK44794.1 - 4.4e-27 95.5 0.0 5.7e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 KKK44794.1 - 0.00016 21.5 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein PBP_like PF12727.7 KKK44794.1 - 0.14 11.2 0.0 0.37 9.9 0.0 1.6 1 1 0 1 1 1 0 PBP superfamily domain Methyltransf_11 PF08241.12 KKK44796.1 - 2.5e-10 40.9 0.0 3.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK44796.1 - 3.3e-10 40.0 0.0 4.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK44796.1 - 4.5e-09 36.9 0.0 8.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK44796.1 - 7.2e-09 36.3 0.0 1.2e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK44796.1 - 3.2e-06 27.1 0.0 4.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK44796.1 - 0.056 13.0 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Lactamase_B PF00753.27 KKK44797.1 - 3.7e-14 53.2 0.0 5.7e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK44797.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fer2_3 PF13085.6 KKK44797.1 - 0.15 12.1 0.0 23 5.1 0.0 2.9 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain DUF1624 PF07786.12 KKK44798.1 - 4e-12 46.2 19.7 4e-12 46.2 19.7 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1624) Acyl_transf_3 PF01757.22 KKK44798.1 - 1.9e-08 33.8 50.2 2.1e-07 30.3 50.2 1.9 1 1 0 1 1 1 1 Acyltransferase family OpgC_C PF10129.9 KKK44798.1 - 5e-07 28.9 3.9 5e-07 28.9 3.9 2.1 2 0 0 2 2 2 1 OpgC protein PMP1_2 PF08114.11 KKK44798.1 - 0.0042 16.8 0.5 0.017 14.9 0.5 2.0 1 0 0 1 1 1 1 ATPase proteolipid family DUF1624 PF07786.12 KKK44799.1 - 6.2e-13 48.8 17.2 6.2e-13 48.8 17.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1624) OpgC_C PF10129.9 KKK44799.1 - 4.3e-06 25.8 5.8 4.3e-06 25.8 5.8 2.8 1 1 1 2 2 2 1 OpgC protein Acyl_transf_3 PF01757.22 KKK44799.1 - 4.6e-05 22.7 44.9 0.00099 18.3 44.9 2.0 1 1 0 1 1 1 1 Acyltransferase family DAO PF01266.24 KKK44803.1 - 2e-45 155.9 0.0 2.2e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK44803.1 - 4.7e-08 32.6 0.2 3.7e-05 23.1 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK44803.1 - 9.9e-08 32.4 1.2 3.2e-05 24.4 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK44803.1 - 6.6e-06 25.6 0.7 0.073 12.3 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK44803.1 - 1.6e-05 24.3 0.4 2.8e-05 23.5 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KKK44803.1 - 2e-05 23.8 0.0 4.2e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KKK44803.1 - 5e-05 23.4 0.5 9.1e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKK44803.1 - 0.00021 20.7 0.1 0.007 15.6 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 KKK44803.1 - 0.00031 19.9 0.1 0.0018 17.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KKK44803.1 - 0.00038 19.3 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein TrkA_N PF02254.18 KKK44803.1 - 0.00069 19.9 0.3 0.0019 18.5 0.2 1.9 1 1 1 2 2 2 1 TrkA-N domain Mqo PF06039.15 KKK44803.1 - 0.0059 15.2 0.0 0.011 14.4 0.0 1.4 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) GDI PF00996.18 KKK44803.1 - 0.017 13.7 0.2 0.089 11.3 0.1 1.9 2 0 0 2 2 2 0 GDP dissociation inhibitor 3HCDH_N PF02737.18 KKK44803.1 - 0.031 14.1 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KKK44803.1 - 0.034 13.8 0.2 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KKK44803.1 - 0.088 13.2 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 KKK44803.1 - 0.098 11.7 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A F420_oxidored PF03807.17 KKK44803.1 - 0.12 13.0 0.1 0.32 11.6 0.1 1.7 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 KKK44803.1 - 0.15 10.9 0.1 3.4 6.4 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 KKK44803.1 - 0.17 11.0 0.1 0.36 9.9 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mon1 PF03164.14 KKK44805.1 - 5e-07 29.1 0.3 5.9e-07 28.9 0.3 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Abhydrolase_1 PF00561.20 KKK44806.1 - 1.1e-08 35.0 0.0 3e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK44806.1 - 0.0066 17.1 0.0 0.0076 16.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK44806.1 - 0.051 12.8 0.0 0.22 10.7 0.0 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KKK44806.1 - 0.078 12.8 0.1 9.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KKK44806.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 2 0 0 2 2 2 0 Putative esterase FAD_binding_4 PF01565.23 KKK44807.1 - 1.6e-14 53.8 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain PfkB PF00294.24 KKK44810.1 - 2.7e-07 30.2 0.0 3e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MannoseP_isomer PF01050.18 KKK44811.1 - 1.2e-07 31.7 0.6 5.5e-07 29.6 0.1 2.1 2 1 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_2 PF07883.11 KKK44811.1 - 0.014 15.1 0.2 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Cupin domain Ribosomal_S19 PF00203.21 KKK44812.1 - 3.3e-30 103.8 0.2 5.9e-30 103.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 KKK44812.1 - 0.033 13.9 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Elongation factor P hydroxylase Ribosomal_L22 PF00237.19 KKK44813.1 - 1.2e-22 80.1 1.0 1.5e-22 79.7 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Herpes_UL36 PF03586.13 KKK44813.1 - 0.05 12.9 0.1 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein XRN_N PF03159.18 KKK44813.1 - 0.081 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus HATPase_c PF02518.26 KKK44816.1 - 1.1e-22 80.7 0.5 2.2e-22 79.7 0.5 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK44816.1 - 4.8e-09 36.1 0.3 7.9e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SirA PF10747.9 KKK44816.1 - 0.0039 17.5 1.3 0.0039 17.5 1.3 2.0 2 0 0 2 2 2 1 Sporulation inhibitor of replication protein SirA HATPase_c_5 PF14501.6 KKK44816.1 - 0.0078 16.1 0.3 0.019 14.9 0.3 1.7 1 0 0 1 1 1 1 GHKL domain ATC_hydrolase PF14196.6 KKK44817.1 - 2.8e-07 31.4 0.3 3e-07 31.3 0.3 1.2 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase CLIP PF12032.8 KKK44817.1 - 0.091 13.1 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases Methyltransf_11 PF08241.12 KKK44818.1 - 6e-17 62.1 0.0 1.1e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK44818.1 - 4.8e-15 55.7 0.0 8e-15 54.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK44818.1 - 8.5e-15 55.2 0.0 1.4e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK44818.1 - 1.1e-14 54.9 0.0 2.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK44818.1 - 2.9e-13 50.0 0.0 3.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK44818.1 - 2.1e-12 46.9 0.0 2.9e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KKK44818.1 - 1.6e-05 24.4 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.10 KKK44818.1 - 0.004 16.7 0.7 0.0067 16.0 0.0 1.7 3 0 0 3 3 3 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 KKK44818.1 - 0.0066 16.1 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KKK44818.1 - 0.0074 16.1 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KKK44818.1 - 0.011 15.0 0.0 0.017 14.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 KKK44818.1 - 0.024 14.3 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 tRNA_U5-meth_tr PF05958.11 KKK44818.1 - 0.027 13.5 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 KKK44818.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 KKK44818.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_17 PF12692.7 KKK44818.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase zinc_ribbon_15 PF17032.5 KKK44819.1 - 0.00018 22.2 0.7 0.00023 21.9 0.7 1.2 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 KKK44819.1 - 0.00022 21.2 1.6 0.00034 20.6 1.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK44819.1 - 0.0034 17.0 6.4 0.0082 15.8 6.1 1.8 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK44819.1 - 0.0048 16.3 3.1 0.87 9.1 0.4 2.3 2 0 0 2 2 2 2 zinc-ribbon domain SCIMP PF15050.6 KKK44819.1 - 0.011 16.3 0.1 0.013 16.0 0.1 1.1 1 0 0 1 1 1 0 SCIMP protein zinc_ribbon_9 PF14369.6 KKK44819.1 - 0.012 15.9 1.1 0.02 15.2 1.1 1.4 1 0 0 1 1 1 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 KKK44819.1 - 0.02 14.8 1.9 0.031 14.2 1.9 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 KKK44819.1 - 0.028 14.6 1.0 0.048 13.8 1.0 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1610 PF07754.11 KKK44819.1 - 0.028 14.4 4.1 0.072 13.1 4.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1610) HypA PF01155.19 KKK44819.1 - 0.086 12.9 0.2 0.096 12.7 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Vps36-NZF-N PF16988.5 KKK44819.1 - 0.12 11.8 3.7 0.92 8.9 0.1 2.4 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Nudix_N_2 PF14803.6 KKK44819.1 - 0.13 12.2 3.1 6.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 KKK44819.1 - 0.21 11.1 4.5 0.75 9.4 4.4 1.9 1 1 1 2 2 2 0 TFIIB zinc-binding zf-C2H2_3 PF13878.6 KKK44819.1 - 0.5 10.2 3.5 12 5.8 0.1 2.5 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO NOB1_Zn_bind PF08772.11 KKK44819.1 - 0.57 10.4 5.0 1.3 9.3 4.0 2.0 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like E1-E2_ATPase PF00122.20 KKK44820.1 - 7.5e-51 172.2 0.8 7.5e-51 172.2 0.8 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK44820.1 - 1.6e-43 149.4 2.5 2.8e-43 148.7 2.5 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KKK44820.1 - 3.8e-10 40.1 0.1 1.8e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KKK44820.1 - 2.1e-07 31.0 0.7 0.00014 21.7 0.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK44820.1 - 3.5e-05 24.3 0.1 0.00025 21.5 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK44820.1 - 0.036 14.2 0.1 0.11 12.5 0.1 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NAD_binding_7 PF13241.6 KKK44820.1 - 0.084 13.3 0.1 0.27 11.7 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Hydrolase_6 PF13344.6 KKK44820.1 - 0.14 12.2 0.0 0.96 9.6 0.0 2.4 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.14 KKK44821.1 - 1.9e-60 204.6 0.5 2.4e-60 204.3 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK44821.1 - 6.3e-28 97.2 0.1 2.1e-26 92.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKK44821.1 - 3.1e-20 72.5 1.6 1.1e-17 64.3 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK44821.1 - 2.8e-12 46.4 7.1 1.6e-10 40.6 2.3 3.4 1 1 2 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK44821.1 - 2.6e-09 36.8 1.6 3.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK44821.1 - 4.2e-09 35.6 7.1 0.00066 18.5 0.3 3.7 3 1 1 4 4 4 3 HI0933-like protein FAD_oxidored PF12831.7 KKK44821.1 - 2.2e-06 27.3 0.2 3.5e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK44821.1 - 5.3e-06 26.6 0.8 0.033 14.4 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KKK44821.1 - 0.00023 20.5 0.5 0.59 9.4 0.4 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KKK44821.1 - 0.00032 19.9 1.0 0.00067 18.8 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK44821.1 - 0.00056 19.6 0.0 0.095 12.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KKK44821.1 - 0.00084 19.3 1.3 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KKK44821.1 - 0.019 14.2 0.1 2.7 7.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KKK44821.1 - 0.022 14.0 0.2 0.14 11.4 0.1 2.2 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 KKK44821.1 - 0.03 13.7 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K_oxygenase PF13434.6 KKK44821.1 - 0.036 13.2 0.3 13 4.8 0.0 2.9 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KKK44821.1 - 0.042 12.9 2.9 0.22 10.5 0.6 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 KKK44821.1 - 0.06 13.3 0.1 0.57 10.1 0.0 2.4 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.14 KKK44821.1 - 0.14 11.0 0.8 0.28 10.0 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Pirin PF02678.16 KKK44822.1 - 2.3e-27 95.1 0.3 3.4e-27 94.5 0.3 1.2 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 KKK44822.1 - 1.2e-10 41.4 0.1 8.7e-10 38.6 0.0 2.2 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 KKK44822.1 - 5.7e-06 26.0 0.5 2.3e-05 24.0 0.4 1.9 2 0 0 2 2 2 1 Cupin domain Response_reg PF00072.24 KKK44823.1 - 4.4e-21 75.2 0.1 4.8e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF4602 PF15375.6 KKK44823.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) NMT1_2 PF13379.6 KKK44824.1 - 6.1e-17 62.2 0.0 6.5e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 KKK44824.1 - 0.0052 16.8 0.0 0.006 16.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like VWA_2 PF13519.6 KKK44828.1 - 5.9e-05 23.7 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KKK44828.1 - 0.0022 17.4 0.0 0.036 13.5 0.0 2.0 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 KKK44828.1 - 0.0027 17.9 0.0 0.0097 16.0 0.0 1.8 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 KKK44828.1 - 0.0094 16.2 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain GSHPx PF00255.19 KKK44828.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase Fer4 PF00037.27 KKK44829.1 - 3.7e-07 29.7 15.0 0.0012 18.6 4.8 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK44829.1 - 3.8e-06 26.7 13.0 0.0018 18.2 3.5 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK44829.1 - 9.1e-05 22.5 11.0 9.1e-05 22.5 11.0 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK44829.1 - 0.00021 21.2 2.6 0.00021 21.2 2.6 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK44829.1 - 0.0049 17.4 0.3 0.0049 17.4 0.3 2.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain AhpC-TSA PF00578.21 KKK44831.1 - 2.3e-19 69.5 0.0 3.2e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK44831.1 - 3.2e-12 46.4 0.0 1.3e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Redoxin AhpC-TSA_2 PF13911.6 KKK44831.1 - 0.0015 18.7 0.3 0.0097 16.0 0.2 2.2 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme ATP-synt_F PF01990.17 KKK44831.1 - 0.11 12.9 0.3 0.22 11.9 0.3 1.6 1 1 0 1 1 1 0 ATP synthase (F/14-kDa) subunit PAC2 PF09754.9 KKK44832.1 - 2.1e-29 103.1 0.1 2.5e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 PAC2 family Fer4_7 PF12838.7 KKK44833.1 - 1.1e-14 54.7 21.1 1.2e-06 29.0 7.0 3.5 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4 PF00037.27 KKK44833.1 - 3.4e-14 52.0 26.4 0.00073 19.3 0.1 4.7 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_10 PF13237.6 KKK44833.1 - 7.7e-14 51.5 23.0 1.4e-07 31.5 6.1 2.5 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44833.1 - 4.2e-11 42.4 27.5 0.0002 21.3 2.0 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_9 PF13187.6 KKK44833.1 - 1.1e-10 41.5 24.8 8.4e-05 22.7 8.6 3.3 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK44833.1 - 3.3e-09 36.3 24.5 0.0034 17.4 1.9 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_21 PF14697.6 KKK44833.1 - 5.4e-09 36.0 28.7 6.3e-07 29.4 7.9 3.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44833.1 - 2.1e-07 31.8 26.7 0.069 14.1 3.1 4.2 2 1 2 4 4 4 3 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 KKK44833.1 - 1.7e-05 25.2 23.2 0.0034 17.9 9.4 3.3 2 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK44833.1 - 0.0013 19.4 18.2 0.21 12.4 0.2 4.4 4 0 0 4 4 4 2 4Fe-4S single cluster domain Fer4_8 PF13183.6 KKK44833.1 - 0.033 14.6 28.7 0.15 12.5 9.3 3.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK44833.1 - 0.15 13.1 1.6 0.15 13.1 1.6 5.0 5 0 0 5 5 5 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK44833.1 - 0.36 11.7 22.2 0.4 11.6 0.5 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK44833.1 - 2.5 8.7 25.7 9.1 6.9 0.5 4.3 4 0 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 KKK44833.1 - 2.9 8.6 34.3 0.45 11.2 2.7 4.8 4 1 0 4 4 4 0 4Fe-4S binding domain ADH_N PF08240.12 KKK44833.1 - 9.4 6.2 15.9 0.16 11.9 6.0 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain His_kinase PF06580.13 KKK44834.1 - 0.023 15.0 1.8 0.037 14.3 0.5 2.0 2 0 0 2 2 2 0 Histidine kinase CpXC PF14353.6 KKK44834.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.6 1 1 0 1 1 1 0 CpXC protein DUF2590 PF10761.9 KKK44834.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) DUF166 PF02593.14 KKK44835.1 - 7e-48 163.1 0.1 8.8e-48 162.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function zf-HIT PF04438.16 KKK44835.1 - 0.0049 16.7 1.1 0.0049 16.7 1.1 2.1 2 0 0 2 2 2 1 HIT zinc finger E1-E2_ATPase PF00122.20 KKK44836.1 - 1.5e-46 158.2 2.7 4.3e-46 156.7 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK44836.1 - 6.9e-36 124.5 0.0 1e-35 123.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK44836.1 - 0.012 15.4 2.5 0.023 14.4 0.5 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK44836.1 - 0.068 13.6 0.0 0.32 11.4 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.25 KKK44837.1 - 5.8e-11 42.7 0.0 7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK44837.1 - 1.5e-09 37.9 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK44837.1 - 6.5e-09 36.1 0.0 8.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK44837.1 - 2.6e-08 33.7 0.0 3.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Gly_acyl_tr_C PF08444.10 KKK44837.1 - 2.3e-05 24.5 0.1 3.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_3 PF13302.7 KKK44837.1 - 0.00071 20.3 0.0 0.0009 19.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK44837.1 - 0.00072 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase MRP-S34 PF16053.5 KKK44837.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 GNAT_acetyltran PF12746.7 KKK44837.1 - 0.023 14.3 0.4 0.028 14.0 0.4 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase ACT PF01842.25 KKK44838.1 - 5.8e-05 22.8 1.3 0.0063 16.3 0.0 2.5 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 KKK44838.1 - 0.0033 17.2 0.1 1.4 8.7 0.0 2.7 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 KKK44838.1 - 0.0034 17.9 0.0 0.045 14.3 0.0 2.1 2 1 0 2 2 2 1 ACT domain Ribosomal_L11_N PF03946.14 KKK44838.1 - 0.11 12.4 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain TPR_12 PF13424.6 KKK44839.1 - 2.2e-35 120.8 12.0 1.4e-09 38.1 0.0 6.8 4 3 4 8 8 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 KKK44839.1 - 2.5e-30 103.5 1.6 0.00018 21.2 0.1 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KKK44839.1 - 5.3e-27 92.5 25.0 1.9e-05 24.2 0.7 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KKK44839.1 - 8.5e-23 78.6 15.2 0.00014 21.7 0.2 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 KKK44839.1 - 3.9e-20 70.3 33.5 0.00096 19.2 0.2 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 KKK44839.1 - 7.2e-16 57.0 12.4 0.0059 16.6 0.0 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KKK44839.1 - 2e-11 44.4 0.0 0.028 15.1 0.0 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KKK44839.1 - 1e-09 38.4 0.0 0.24 12.3 0.0 6.8 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK44839.1 - 9.9e-08 32.4 7.7 1.4 9.5 0.3 5.2 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 KKK44839.1 - 1.2e-05 25.3 8.8 10 6.7 0.2 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK44839.1 - 1.6e-05 24.5 0.0 0.0023 17.4 0.0 2.9 2 2 0 2 2 2 1 MalT-like TPR region TPR_11 PF13414.6 KKK44839.1 - 0.033 13.9 21.1 5.4 6.8 0.1 7.2 6 2 0 7 7 7 0 TPR repeat TPR_21 PF09976.9 KKK44839.1 - 0.034 13.9 0.2 54 3.4 0.0 4.1 2 2 3 5 5 5 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KKK44839.1 - 0.071 13.8 9.3 52 4.8 0.0 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 KKK44839.1 - 0.24 11.7 4.1 1.1e+02 3.4 0.0 5.2 6 0 0 6 6 6 0 PPR repeat HhH-GPD PF00730.25 KKK44840.1 - 0.013 16.0 0.0 0.035 14.6 0.0 1.7 2 1 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein SNARE_assoc PF09335.11 KKK44843.1 - 4.1e-08 33.7 1.6 4.1e-08 33.7 1.6 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2304 PF10066.9 KKK44843.1 - 4 7.7 13.8 7.5 6.8 9.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) RDD PF06271.12 KKK44845.1 - 2.4e-14 53.7 0.5 3.1e-14 53.4 0.5 1.1 1 0 0 1 1 1 1 RDD family zinc_ribbon_2 PF13240.6 KKK44845.1 - 1.5e-07 30.9 4.9 2.3e-07 30.3 4.9 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK44845.1 - 9.5e-07 28.0 2.5 1.4e-06 27.4 2.5 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK44845.1 - 2.3e-06 27.5 0.9 3.4e-06 27.0 0.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KKK44845.1 - 0.0003 20.6 1.2 0.11 12.5 0.2 2.4 2 0 0 2 2 2 2 Nudix N-terminal RNA_POL_M_15KD PF02150.16 KKK44845.1 - 0.0069 16.2 7.4 0.14 12.1 7.4 2.3 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit zinc_ribbon_15 PF17032.5 KKK44845.1 - 0.017 15.8 2.1 0.031 15.0 2.1 1.3 1 0 0 1 1 1 0 zinc-ribbon family zf-NADH-PPase PF09297.11 KKK44845.1 - 0.096 12.4 2.7 0.56 9.9 0.2 2.2 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain UPF0547 PF10571.9 KKK44845.1 - 0.14 12.3 2.5 0.29 11.3 2.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF2116 PF09889.9 KKK44845.1 - 0.22 11.5 0.4 0.44 10.6 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DHHC PF01529.20 KKK44845.1 - 0.62 10.2 2.3 0.56 10.3 0.2 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase NOB1_Zn_bind PF08772.11 KKK44845.1 - 0.72 10.1 8.7 0.95 9.7 1.2 2.6 2 1 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like ECH_1 PF00378.20 KKK44846.1 - 3.6e-56 190.3 0.0 4.2e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK44846.1 - 3.4e-30 105.7 0.0 6.9e-28 98.1 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Methyltransf_11 PF08241.12 KKK44847.1 - 3.5e-13 50.0 0.0 5.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK44847.1 - 1.1e-11 45.2 0.0 1.8e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK44847.1 - 6.7e-08 32.5 0.0 8.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK44847.1 - 1.4e-07 31.5 0.2 5.4e-07 29.5 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK44847.1 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KKK44847.1 - 0.00044 20.9 0.0 0.00068 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 KKK44847.1 - 0.0022 17.1 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 KKK44847.1 - 0.027 13.9 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 KKK44847.1 - 0.085 12.1 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KKK44847.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 KKK44847.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cpn60_TCP1 PF00118.24 KKK44850.1 - 6.2e-10 38.3 1.0 6.6e-10 38.2 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GIY-YIG PF01541.24 KKK44851.1 - 4.1e-10 39.8 5.0 1.9e-09 37.7 5.0 2.2 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF87 PF01935.17 KKK44852.1 - 4.5e-06 26.9 0.3 9.8e-06 25.8 0.3 1.7 1 1 0 1 1 1 1 Helicase HerA, central domain Pox_A32 PF04665.12 KKK44852.1 - 0.0002 20.9 0.1 0.0004 19.9 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein ATPase_2 PF01637.18 KKK44852.1 - 0.0041 17.1 0.5 0.01 15.8 0.5 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KKK44852.1 - 0.0089 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KKK44852.1 - 0.0096 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 KKK44852.1 - 0.019 14.8 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KKK44852.1 - 0.025 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK44852.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 KKK44852.1 - 0.046 13.1 0.1 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.15 KKK44852.1 - 0.091 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KKK44852.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KKK44852.1 - 0.16 12.4 0.0 0.47 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Phage_int_SAM_4 PF13495.6 KKK44852.1 - 0.25 11.8 1.9 0.35 11.4 0.3 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain SNase PF00565.17 KKK44854.1 - 4.7e-12 46.3 0.1 1.2e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Staphylococcal nuclease homologue tRNA_anti-codon PF01336.25 KKK44854.1 - 2.1e-07 30.9 0.3 7.7e-07 29.0 0.2 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KKK44854.1 - 8.4e-06 25.7 1.7 2e-05 24.4 0.2 2.3 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 POT1PC PF16686.5 KKK44854.1 - 0.014 15.2 0.1 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein FIVAR PF07554.13 KKK44854.1 - 0.44 11.3 3.0 1.1 10.1 3.0 1.7 1 0 0 1 1 1 0 FIVAR domain E3_binding PF02817.17 KKK44854.1 - 0.44 10.9 2.0 0.78 10.1 0.0 2.4 3 0 0 3 3 3 0 e3 binding domain DUF4974 PF16344.5 KKK44855.1 - 0.0035 17.3 0.6 0.0048 16.9 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) DUF285 PF03382.14 KKK44856.1 - 4.4e-304 988.4 203.1 4.5e-41 139.4 17.4 9.8 3 1 8 11 11 11 9 Mycoplasma protein of unknown function, DUF285 Mucin_bdg PF03272.13 KKK44856.1 - 4.5e-05 23.4 4.9 9.3 6.3 0.0 5.4 5 0 0 5 5 5 2 Putative mucin or carbohydrate-binding module PKD PF00801.20 KKK44856.1 - 0.023 14.5 0.6 0.023 14.5 0.6 8.4 6 3 0 6 6 6 0 PKD domain DUF987 PF06174.11 KKK44856.1 - 0.93 9.5 21.6 59 3.7 0.1 7.2 7 0 0 7 7 7 0 Protein of unknown function (DUF987) HYR PF02494.16 KKK44856.1 - 9.2 6.7 34.9 5.8 7.3 0.5 8.8 6 2 3 9 9 9 0 HYR domain DUF87 PF01935.17 KKK44857.1 - 1.1e-07 32.2 3.4 1.5e-07 31.8 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KKK44857.1 - 5.6e-07 29.2 0.0 1.3e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF853 PF05872.12 KKK44857.1 - 0.00013 20.7 0.0 0.00022 19.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 KKK44857.1 - 0.00014 22.1 0.0 0.00051 20.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK44857.1 - 0.00014 21.4 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 KKK44857.1 - 0.00055 19.0 0.0 0.00096 18.2 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KKK44857.1 - 0.0006 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Pox_A32 PF04665.12 KKK44857.1 - 0.0025 17.3 0.9 0.0025 17.3 0.9 1.9 2 0 0 2 2 2 1 Poxvirus A32 protein ATPase PF06745.13 KKK44857.1 - 0.0028 17.1 0.8 0.0045 16.4 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_32 PF13654.6 KKK44857.1 - 0.027 13.3 2.1 0.2 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK44857.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KKK44857.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Uds1 PF15456.6 KKK44857.1 - 0.12 12.5 1.8 0.26 11.5 1.8 1.5 1 0 0 1 1 1 0 Up-regulated During Septation AAA_29 PF13555.6 KKK44857.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KKK44857.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF3810 PF12725.7 KKK44857.1 - 8.5 5.6 9.7 1.7 7.9 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Methyltransf_11 PF08241.12 KKK44860.1 - 3.9e-21 75.5 0.0 6.3e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK44860.1 - 1.3e-18 67.5 0.0 2.1e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK44860.1 - 2.2e-17 63.3 0.5 3.4e-17 62.7 0.4 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK44860.1 - 3.2e-15 56.3 0.0 4.4e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK44860.1 - 7.3e-15 55.5 0.0 1.7e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK44860.1 - 5.7e-10 38.9 0.4 7.4e-10 38.5 0.4 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KKK44860.1 - 1.6e-09 37.5 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KKK44860.1 - 3.2e-07 29.9 0.2 5.6e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 KKK44860.1 - 2.2e-06 27.4 0.0 3.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 KKK44860.1 - 3.1e-06 26.8 0.0 5.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KKK44860.1 - 3.3e-06 26.6 0.1 4.6e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KKK44860.1 - 4.3e-06 25.9 0.0 7.7e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 KKK44860.1 - 4.6e-05 23.1 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 KKK44860.1 - 7e-05 22.4 1.5 0.1 12.1 0.1 3.0 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 KKK44860.1 - 0.0001 22.4 0.3 0.00015 21.8 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KKK44860.1 - 0.00024 20.9 5.1 0.047 13.4 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Methyltransf_18 PF12847.7 KKK44860.1 - 0.00035 20.5 1.3 0.00052 20.0 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 KKK44860.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) STAT2_C PF12188.8 KKK44860.1 - 0.0022 17.9 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 Signal transducer and activator of transcription 2 C terminal PCMT PF01135.19 KKK44860.1 - 0.0034 17.2 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 KKK44860.1 - 0.0045 16.1 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.18 KKK44860.1 - 0.027 14.1 0.1 0.12 12.0 0.1 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 UPF0146 PF03686.13 KKK44860.1 - 0.083 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) NosD PF05048.13 KKK44861.1 - 7.1e-05 22.2 11.3 7.7e-05 22.1 11.3 1.0 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK44861.1 - 0.00057 19.8 13.7 0.00064 19.6 13.7 1.0 1 0 0 1 1 1 1 Right handed beta helix region Succ_CoA_lig PF13607.6 KKK44863.1 - 8.8e-22 77.4 0.0 1.1e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain DUF2196 PF09962.9 KKK44864.1 - 3.7e-28 97.3 2.1 4.1e-28 97.1 2.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Acetyltransf_3 PF13302.7 KKK44865.1 - 9.1e-10 39.3 0.0 1.2e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK44865.1 - 1.3e-09 38.3 0.1 1.6e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK44865.1 - 4.3e-06 26.7 0.3 1.4e-05 25.0 0.3 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK44865.1 - 1.1e-05 25.7 0.1 1.5e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK44865.1 - 0.00018 21.7 0.4 0.00058 20.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 KKK44865.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Baculo_VP39 PF04501.12 KKK44865.1 - 0.035 13.6 0.4 0.041 13.4 0.4 1.2 1 0 0 1 1 1 0 Baculovirus major capsid protein VP39 FR47 PF08445.10 KKK44865.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein SF3A3 PF16837.5 KKK44865.1 - 0.087 13.4 0.2 0.17 12.4 0.2 1.7 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 DEAD PF00270.29 KKK44866.1 - 1.1e-52 178.4 0.3 9.6e-51 172.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK44866.1 - 5.5e-31 107.2 2.0 7e-29 100.4 0.5 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CSD PF00313.22 KKK44866.1 - 3.6e-17 62.0 0.1 7.5e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain ERCC3_RAD25_C PF16203.5 KKK44866.1 - 0.0012 18.1 0.3 0.0025 17.1 0.3 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase OB_RNB PF08206.11 KKK44866.1 - 0.0075 15.9 0.1 0.021 14.5 0.1 1.8 1 0 0 1 1 1 1 Ribonuclease B OB domain SUa-2TM PF18179.1 KKK44866.1 - 0.02 14.2 0.2 0.036 13.4 0.2 1.4 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain ResIII PF04851.15 KKK44866.1 - 0.024 14.6 0.0 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Fe-ADH PF00465.19 KKK44866.1 - 0.092 11.5 0.1 1.6 7.4 0.1 2.6 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase DZR PF12773.7 KKK44868.1 - 0.038 14.0 0.8 0.065 13.3 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK44868.1 - 0.047 13.1 2.8 0.1 12.0 2.8 1.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.8 KKK44868.1 - 0.75 9.7 1.9 1.2 9.0 1.9 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 KKK44868.1 - 7.9 6.3 7.0 51 3.8 7.4 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Rib_5-P_isom_A PF06026.14 KKK44869.1 - 7.6e-65 217.7 0.1 1.1e-64 217.3 0.1 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KKK44869.1 - 0.0075 16.2 0.5 0.29 11.1 0.1 2.1 1 1 1 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.13 KKK44869.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain AIRC PF00731.20 KKK44870.1 - 8.7e-47 158.4 0.3 9.7e-47 158.3 0.3 1.0 1 0 0 1 1 1 1 AIR carboxylase Fer4 PF00037.27 KKK44873.1 - 0.00047 19.9 5.2 0.0066 16.2 2.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain DIX PF00778.17 KKK44873.1 - 0.056 13.3 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 DIX domain Phi-29_GP16_7 PF06720.11 KKK44874.1 - 0.033 14.0 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 AhpC-TSA PF00578.21 KKK44875.1 - 5.1e-19 68.4 0.0 7.4e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KKK44875.1 - 1.2e-14 54.2 0.0 1.4e-10 41.0 0.0 2.0 1 1 1 2 2 2 2 Redoxin AhpC-TSA_2 PF13911.6 KKK44875.1 - 5e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme PAC2 PF09754.9 KKK44876.1 - 5.2e-30 105.1 0.1 6.1e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 PAC2 family Fer4 PF00037.27 KKK44878.1 - 1.5e-13 49.9 26.2 1.6e-07 30.8 1.3 4.6 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_10 PF13237.6 KKK44878.1 - 1.2e-12 47.7 21.2 1.8e-08 34.4 9.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK44878.1 - 2.5e-12 47.2 20.3 4.3e-07 30.4 10.8 3.2 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44878.1 - 2e-09 37.1 29.9 0.00029 20.8 1.6 4.5 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 KKK44878.1 - 9.4e-09 35.3 31.9 1.4e-07 31.6 11.2 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK44878.1 - 9.6e-09 35.3 24.3 1.3e-05 25.2 13.2 3.3 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK44878.1 - 2.1e-08 33.8 26.8 0.0012 18.9 2.7 4.1 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_16 PF13484.6 KKK44878.1 - 7.9e-05 23.5 24.9 0.029 15.3 0.8 4.0 2 1 2 4 4 4 2 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 KKK44878.1 - 0.0066 17.2 17.6 0.73 10.6 0.2 3.8 4 0 0 4 4 4 3 4Fe-4S single cluster domain Fer4_17 PF13534.6 KKK44878.1 - 0.0094 16.5 24.2 1.1 9.9 0.8 3.4 2 1 1 3 3 3 3 4Fe-4S dicluster domain ADH_N PF08240.12 KKK44878.1 - 0.023 14.6 2.0 0.023 14.6 2.0 2.8 1 1 1 2 2 1 0 Alcohol dehydrogenase GroES-like domain Fer4_8 PF13183.6 KKK44878.1 - 3.9 8.0 29.0 1.6 9.2 3.9 3.7 2 2 2 4 4 4 0 4Fe-4S dicluster domain His_kinase PF06580.13 KKK44879.1 - 0.033 14.5 1.5 0.053 13.8 0.5 1.8 2 0 0 2 2 2 0 Histidine kinase PhnA_Zn_Ribbon PF08274.12 KKK44879.1 - 0.05 13.6 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF166 PF02593.14 KKK44880.1 - 5.2e-48 163.5 0.1 6.7e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function zf-HIT PF04438.16 KKK44880.1 - 0.0049 16.7 1.1 0.0049 16.7 1.1 2.5 3 0 0 3 3 3 1 HIT zinc finger E1-E2_ATPase PF00122.20 KKK44881.1 - 6.8e-46 156.1 2.8 1.8e-45 154.7 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK44881.1 - 1e-36 127.2 0.0 1.8e-36 126.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK44881.1 - 0.021 15.3 0.0 0.079 13.4 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK44881.1 - 0.031 14.0 0.1 0.031 14.0 0.1 2.5 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase Sdh_cyt PF01127.22 KKK44881.1 - 5 7.2 10.2 7.6 6.6 1.0 2.7 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ACT PF01842.25 KKK44882.1 - 1.6e-05 24.6 0.4 0.0028 17.4 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KKK44882.1 - 0.0032 17.2 0.1 2.3 8.1 0.0 2.9 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 KKK44882.1 - 0.015 15.8 0.1 0.2 12.2 0.0 2.2 2 1 0 2 2 2 0 ACT domain TPR_10 PF13374.6 KKK44883.1 - 3.5e-31 106.2 6.8 1.3e-06 28.0 0.2 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KKK44883.1 - 4.6e-30 103.7 14.2 2.2e-08 34.3 0.0 6.8 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KKK44883.1 - 1.3e-22 78.6 23.3 0.00055 19.6 0.3 9.3 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 KKK44883.1 - 1e-18 65.9 28.9 0.003 17.6 0.3 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 KKK44883.1 - 4.8e-18 63.8 12.3 0.033 14.2 0.0 7.9 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KKK44883.1 - 1.3e-17 62.4 18.9 0.0069 16.4 0.3 8.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KKK44883.1 - 2e-10 40.6 0.3 0.43 11.5 0.0 5.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK44883.1 - 1.6e-09 38.2 0.0 0.0017 18.9 0.0 4.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KKK44883.1 - 8.3e-08 32.1 12.1 0.25 11.8 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK44883.1 - 6e-07 29.9 8.2 0.67 10.5 0.8 5.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK44883.1 - 0.0017 18.0 12.5 0.43 10.3 0.0 6.2 6 1 0 6 6 6 2 TPR repeat TPR_MalT PF17874.1 KKK44883.1 - 0.006 16.0 0.0 0.71 9.2 0.0 2.8 2 2 1 3 3 3 1 MalT-like TPR region PPR PF01535.20 KKK44883.1 - 0.061 13.6 1.0 19 5.8 0.0 4.8 5 0 0 5 5 5 0 PPR repeat DUF2795 PF11387.8 KKK44883.1 - 0.55 10.5 0.1 0.55 10.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) PadR PF03551.14 KKK44883.1 - 0.71 9.9 6.3 6 6.9 0.9 3.5 2 1 1 3 3 3 0 Transcriptional regulator PadR-like family TPR_6 PF13174.6 KKK44883.1 - 3.4 8.5 10.7 53 4.7 0.1 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat PBP1_TM PF14812.6 KKK44886.1 - 0.052 13.9 0.3 0.07 13.5 0.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNARE_assoc PF09335.11 KKK44887.1 - 1.6e-08 35.0 4.3 2.8e-08 34.3 1.6 2.3 1 1 1 2 2 2 1 SNARE associated Golgi protein LrgA PF03788.14 KKK44887.1 - 2.7 8.0 10.9 3.2 7.8 1.4 3.0 3 1 0 3 3 3 0 LrgA family MFS_2 PF13347.6 KKK44888.1 - 7.6e-12 44.5 2.8 8.3e-12 44.4 2.8 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein EI24 PF07264.11 KKK44888.1 - 0.0048 17.2 0.9 0.0054 17.0 0.9 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) RDD PF06271.12 KKK44890.1 - 2.6e-06 27.7 0.0 3.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 RDD family CBFD_NFYB_HMF PF00808.23 KKK44894.1 - 2.2e-08 34.3 0.0 2.3e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KKK44894.1 - 0.00019 21.8 0.2 0.00022 21.6 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KKK44894.1 - 0.00027 21.3 0.0 0.00028 21.2 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KKK44894.1 - 0.00043 20.3 0.0 0.00049 20.2 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KKK44894.1 - 0.00089 19.4 0.1 0.001 19.1 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KKK44894.1 - 0.03 14.3 0.1 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Bromodomain associated TAF PF02969.17 KKK44894.1 - 0.075 13.2 0.2 0.077 13.2 0.2 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Proteasome PF00227.26 KKK44895.1 - 3.3e-48 163.7 0.5 3.7e-48 163.5 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-RING_2 PF13639.6 KKK44896.1 - 0.00038 20.7 8.4 0.00062 20.0 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KKK44896.1 - 0.00059 20.1 5.6 0.0012 19.1 5.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 KKK44896.1 - 0.0043 17.0 9.5 0.045 13.7 9.8 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.29 KKK44896.1 - 0.0073 16.2 7.3 0.012 15.4 7.3 1.4 1 0 0 1 1 1 1 PHD-finger HSBP1 PF06825.12 KKK44896.1 - 0.018 14.9 3.2 34 4.4 0.1 5.3 5 0 0 5 5 5 0 Heat shock factor binding protein 1 DIT1_PvcA PF05141.12 KKK44896.1 - 0.045 13.2 3.1 0.034 13.6 0.4 2.1 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein P22_AR_C PF10548.9 KKK44896.1 - 0.074 13.2 1.0 0.59 10.3 0.0 3.1 3 1 0 3 3 3 0 P22AR C-terminal domain DUF4347 PF14252.6 KKK44896.1 - 0.081 12.8 1.5 9 6.1 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Prok-RING_4 PF14447.6 KKK44896.1 - 0.086 12.7 7.5 0.79 9.6 0.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 COMMD1_N PF17221.3 KKK44896.1 - 0.091 13.1 7.0 0.24 11.7 0.0 3.5 3 0 0 3 3 3 0 COMMD1 N-terminal domain DUF1451 PF07295.11 KKK44896.1 - 0.094 12.8 7.2 0.3 11.1 0.1 4.1 3 1 1 4 4 4 0 Zinc-ribbon containing domain DUF4743 PF15916.5 KKK44896.1 - 0.1 12.6 0.2 0.3 11.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) UBZ_FAAP20 PF15750.5 KKK44896.1 - 0.11 12.4 2.5 0.35 10.9 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-C3HC4_2 PF13923.6 KKK44896.1 - 0.11 12.3 8.8 0.2 11.5 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 KKK44896.1 - 0.17 12.2 2.9 11 6.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon zf-C3HC4_3 PF13920.6 KKK44896.1 - 0.36 10.7 6.4 0.63 9.9 6.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF745 PF05335.13 KKK44896.1 - 0.36 10.5 0.5 1.1 9.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) zf-RING_9 PF13901.6 KKK44896.1 - 0.42 10.6 10.3 0.021 14.8 2.4 2.7 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon Zn_ribbon_17 PF17120.5 KKK44896.1 - 0.73 9.5 7.1 1.2 8.8 7.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-CHCC PF10276.9 KKK44896.1 - 0.97 9.5 3.6 0.63 10.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain A2L_zn_ribbon PF08792.10 KKK44896.1 - 1.3 8.8 8.3 0.11 12.2 2.6 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.22 KKK44896.1 - 1.6 8.7 7.8 0.47 10.4 4.0 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPACA9 PF15120.6 KKK44896.1 - 1.8 8.3 8.0 0.61 9.8 1.4 3.1 2 2 0 2 2 2 0 Sperm acrosome-associated protein 9 Zf_RING PF16744.5 KKK44896.1 - 1.9 8.6 4.6 4.8 7.4 4.6 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger GLE1 PF07817.13 KKK44896.1 - 3.5 6.8 7.6 7.6 5.7 0.5 3.0 3 0 0 3 3 3 0 GLE1-like protein DUF1192 PF06698.11 KKK44896.1 - 4.9 7.3 9.8 1.4 9.0 0.7 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) FANCL_C PF11793.8 KKK44896.1 - 5.3 7.3 7.5 16 5.8 7.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2695 PF10905.8 KKK44897.1 - 4e-05 23.7 0.2 0.00015 21.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2695) zf-piccolo PF05715.13 KKK44897.1 - 0.00089 19.4 1.7 0.0014 18.7 1.7 1.4 1 0 0 1 1 1 1 Piccolo Zn-finger NinD PF17466.2 KKK44897.1 - 0.011 15.7 0.5 0.02 15.0 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function LysE PF01810.18 KKK44898.1 - 1.5e-28 99.6 12.4 1.7e-28 99.4 12.4 1.1 1 0 0 1 1 1 1 LysE type translocator DUF5305 PF17231.2 KKK44898.1 - 5.8 6.3 5.0 4.9 6.5 0.5 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5305) EMC3_TMCO1 PF01956.16 KKK44899.1 - 0.012 15.3 1.2 0.018 14.7 1.1 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF3671 PF12420.8 KKK44899.1 - 0.019 15.0 1.0 0.019 15.0 1.0 2.3 2 1 0 3 3 3 0 Protein of unknown function ApoLp-III PF07464.11 KKK44899.1 - 0.037 14.1 5.3 0.096 12.8 5.3 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4349 PF14257.6 KKK44899.1 - 0.04 13.3 0.1 0.11 12.0 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Prominin PF05478.11 KKK44899.1 - 0.077 10.9 0.1 0.091 10.7 0.1 1.1 1 0 0 1 1 1 0 Prominin SF-assemblin PF06705.11 KKK44899.1 - 0.15 11.4 7.9 1.8 7.8 7.5 1.9 1 1 1 2 2 2 0 SF-assemblin/beta giardin Glyco_hydro_77 PF02446.17 KKK44899.1 - 0.46 9.3 11.6 0.51 9.1 11.6 1.0 1 0 0 1 1 1 0 4-alpha-glucanotransferase RapH_N PF18801.1 KKK44899.1 - 0.74 9.9 5.0 4.5 7.4 4.6 2.1 1 1 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal YtxH PF12732.7 KKK44899.1 - 2.6 8.7 4.8 21 5.7 4.8 2.2 1 1 0 1 1 1 0 YtxH-like protein Aminotran_1_2 PF00155.21 KKK44900.1 - 8.7e-33 114.0 0.0 1.2e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK44900.1 - 0.07 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V HGD-D PF06050.13 KKK44900.1 - 0.073 12.8 0.1 4.6 6.9 0.0 2.1 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF2175 PF09943.9 KKK44900.1 - 0.14 12.4 2.2 13 6.2 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) YkyA PF10368.9 KKK44900.1 - 2.2 7.9 7.1 11 5.6 0.2 2.8 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Gelsolin PF00626.22 KKK44901.1 - 4.4e-25 87.4 0.1 1.1e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 Gelsolin repeat DUF4743 PF15916.5 KKK44902.1 - 0.31 11.0 2.8 1.5 8.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) HMMR_N PF15905.5 KKK44902.1 - 6.9 6.0 71.3 0.53 9.7 20.2 3.2 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal GtrA PF04138.14 KKK44903.1 - 4.8e-12 46.1 10.1 5.8e-12 45.9 3.4 2.3 1 1 1 2 2 2 1 GtrA-like protein Polysacc_synt_C PF14667.6 KKK44903.1 - 0.0079 16.3 7.5 0.14 12.2 7.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain 5TM-5TMR_LYT PF07694.12 KKK44903.1 - 0.083 12.4 3.3 1.2 8.7 0.1 2.2 1 1 0 2 2 2 0 5TMR of 5TMR-LYT IBV_3A PF03617.13 KKK44903.1 - 0.22 11.5 1.6 0.53 10.3 1.6 1.6 1 0 0 1 1 1 0 IBV 3A protein EMC3_TMCO1 PF01956.16 KKK44904.1 - 0.0024 17.6 13.4 0.018 14.8 12.1 2.4 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF2207 PF09972.9 KKK44904.1 - 1.9 7.1 4.9 2.7 6.7 4.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Radical_SAM PF04055.21 KKK44905.1 - 7.6e-21 75.2 0.0 2.1e-20 73.8 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK44905.1 - 2e-07 31.4 0.0 3.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK44905.1 - 0.00035 20.7 0.0 0.00093 19.3 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.6 KKK44905.1 - 0.0011 19.4 0.8 0.022 15.3 0.3 2.5 2 0 0 2 2 2 1 Iron-sulfur cluster-binding domain ERM PF00769.19 KKK44910.1 - 9.6e-06 25.6 18.4 1.1e-05 25.4 18.4 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF874 PF05917.11 KKK44910.1 - 0.32 10.0 15.8 0.67 8.9 15.8 1.5 1 1 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF724 PF05266.14 KKK44910.1 - 0.55 10.0 19.6 1.4 8.7 19.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.11 KKK44910.1 - 1.1 9.6 18.8 1.9 8.8 16.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 KKK44910.1 - 1.2 9.7 29.2 4.6 7.8 29.2 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 KKK44910.1 - 1.7 7.9 15.2 1.5 8.0 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 KKK44910.1 - 1.7 8.1 7.8 2.3 7.7 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4164 PF13747.6 KKK44910.1 - 2.2 8.6 15.4 4.9 7.5 2.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) zf-C4H2 PF10146.9 KKK44910.1 - 3.9 7.7 19.2 5.6 7.2 18.1 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein YabA PF06156.13 KKK44910.1 - 4.3 8.0 18.5 1.8 9.3 5.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 KKK44910.1 - 4.8 5.0 9.2 6.1 4.6 9.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.16 KKK44911.1 - 1.5e-12 47.1 9.7 1.9e-12 46.8 9.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ycf66_N PF07444.11 KKK44911.1 - 0.004 17.3 0.4 0.014 15.5 0.4 2.0 1 0 0 1 1 1 1 Ycf66 protein N-terminus Halogen_Hydrol PF10112.9 KKK44911.1 - 0.066 13.2 1.0 0.39 10.7 0.3 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4083 PF13314.6 KKK44913.1 - 1.1 9.3 10.3 0.46 10.5 2.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF3792 PF12670.7 KKK44913.1 - 2.2 8.4 17.3 22 5.2 18.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) DUF308 PF03729.13 KKK44913.1 - 3.3 8.1 14.0 0.16 12.4 6.0 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Glycophorin_A PF01102.18 KKK44913.1 - 5.3 7.3 4.6 24 5.2 1.2 2.3 2 0 0 2 2 2 0 Glycophorin A GT87 PF09594.10 KKK44915.1 - 2.1e-12 47.3 6.7 2.1e-12 47.3 6.7 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 87 PMT_2 PF13231.6 KKK44915.1 - 0.00033 20.9 15.2 0.00033 20.9 15.2 3.7 3 1 1 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Tmemb_14 PF03647.13 KKK44915.1 - 0.0018 19.0 0.4 0.0018 19.0 0.4 3.1 2 2 0 2 2 2 1 Transmembrane proteins 14C His_biosynth PF00977.21 KKK44916.1 - 6.9e-65 218.7 0.1 7.8e-65 218.5 0.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 KKK44916.1 - 3.2e-08 33.3 1.0 0.00072 19.1 0.0 2.3 2 1 0 2 2 2 2 PcrB family Dus PF01207.17 KKK44916.1 - 0.00012 21.3 0.0 0.075 12.1 0.0 2.1 1 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 KKK44916.1 - 0.00075 18.7 0.3 0.061 12.5 0.1 2.1 1 1 1 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 KKK44916.1 - 0.0014 17.7 0.0 0.7 8.8 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK44916.1 - 0.0019 17.3 0.1 0.15 11.0 0.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IGPS PF00218.21 KKK44916.1 - 0.004 16.4 0.0 0.031 13.5 0.0 2.0 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase CutC PF03932.14 KKK44916.1 - 0.0042 16.6 0.3 0.89 9.0 0.0 3.1 1 1 1 3 3 3 1 CutC family Ribul_P_3_epim PF00834.19 KKK44916.1 - 0.0048 16.3 0.1 0.85 9.0 0.1 2.2 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.21 KKK44916.1 - 0.0066 15.7 0.2 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase DsbD_2 PF13386.6 KKK44917.1 - 9.3e-11 42.0 12.1 5.3e-08 33.0 5.2 2.2 1 1 1 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DUF3087 PF11286.8 KKK44917.1 - 9.1 5.7 5.8 1.2 8.6 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3087) PCI PF01399.27 KKK44918.1 - 2.4e-18 66.6 11.0 1.8e-05 25.2 0.0 5.5 1 1 4 5 5 5 4 PCI domain DDRGK PF09756.9 KKK44918.1 - 1e-16 61.1 14.6 1.7e-06 27.7 2.1 4.6 1 1 2 4 4 4 4 DDRGK domain E3_UFM1_ligase PF09743.9 KKK44918.1 - 5.4e-16 59.0 11.0 7.8e-15 55.2 5.4 2.3 1 1 0 2 2 2 2 E3 UFM1-protein ligase 1 FeoC PF09012.10 KKK44918.1 - 3.7e-06 26.9 0.3 1.4 9.1 0.1 4.4 4 0 0 4 4 4 2 FeoC like transcriptional regulator Ribosomal_S25 PF03297.15 KKK44918.1 - 4e-06 27.0 9.2 0.0006 20.0 0.4 4.5 1 1 3 4 4 4 2 S25 ribosomal protein DUF977 PF06163.11 KKK44918.1 - 0.00062 19.7 0.8 0.12 12.4 0.0 3.1 2 1 0 3 3 3 1 Bacterial protein of unknown function (DUF977) HTH_DeoR PF08220.12 KKK44918.1 - 0.00075 19.2 0.1 0.83 9.4 0.0 4.1 4 0 0 4 4 4 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 KKK44918.1 - 0.0036 16.8 0.1 0.36 10.4 0.0 2.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 KKK44918.1 - 0.0092 16.3 1.3 7.6 7.0 0.0 4.1 4 0 0 4 4 4 1 Transcriptional regulator HTH_11 PF08279.12 KKK44918.1 - 0.02 14.8 0.1 7.2 6.6 0.0 3.2 2 0 0 2 2 2 0 HTH domain Sigma70_r4 PF04545.16 KKK44918.1 - 0.12 11.9 0.1 6.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_9 PF08221.11 KKK44918.1 - 0.3 11.2 2.8 7.7 6.7 0.0 3.9 5 0 0 5 5 5 0 RNA polymerase III subunit RPC82 helix-turn-helix domain zf_Rg PF17915.1 KKK44918.1 - 1.2 8.6 3.9 20 4.7 0.1 2.6 2 0 0 2 2 2 0 Reverse gyrase zinc finger zf-C4_Topoisom PF01396.19 KKK44918.1 - 1.8 8.4 11.3 0.093 12.5 0.7 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-AN1 PF01428.16 KKK44918.1 - 4.2 7.6 19.1 0.056 13.6 11.0 2.1 2 0 0 2 2 1 0 AN1-like Zinc finger PPC PF04151.15 KKK44921.1 - 0.0021 19.1 0.4 0.0077 17.3 0.4 1.9 1 0 0 1 1 1 1 Bacterial pre-peptidase C-terminal domain Invasin_D3 PF09134.10 KKK44921.1 - 0.0052 17.1 2.3 0.016 15.5 0.5 2.6 3 1 0 3 3 3 1 Invasin, domain 3 Filamin PF00630.19 KKK44921.1 - 0.12 13.2 0.0 0.78 10.6 0.0 2.4 1 1 1 2 2 2 0 Filamin/ABP280 repeat DUF5478 PF17572.2 KKK44921.1 - 0.18 12.0 3.2 0.21 11.7 1.2 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5478) RuBisCO_large PF00016.20 KKK44923.1 - 3.9e-57 193.7 0.0 8e-57 192.7 0.0 1.5 1 1 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RuBisCO_large_N PF02788.16 KKK44923.1 - 1.3e-08 35.1 0.0 3.4e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain zf-ribbon_3 PF13248.6 KKK44924.1 - 0.01 15.2 2.1 0.55 9.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 KKK44924.1 - 0.032 14.3 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Spt4 PF06093.13 KKK44924.1 - 0.04 14.0 0.3 0.11 12.6 0.3 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger PyrI_C PF02748.15 KKK44924.1 - 0.063 13.2 0.1 0.24 11.3 0.1 2.0 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_2 PF13240.6 KKK44924.1 - 0.075 12.8 1.9 3.8 7.3 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-RRPl_C4 PF17026.5 KKK44924.1 - 0.24 11.5 5.8 0.32 11.1 4.5 1.8 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type OrfB_Zn_ribbon PF07282.11 KKK44924.1 - 0.29 11.1 0.1 0.29 11.1 0.1 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Aminotran_1_2 PF00155.21 KKK44925.1 - 1.7e-46 159.1 0.0 2e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KKK44925.1 - 7e-05 21.9 0.1 0.00014 20.8 0.1 1.5 1 1 1 2 2 2 1 Allinase RNase_Zc3h12a PF11977.8 KKK44925.1 - 0.0054 16.5 0.0 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain Cys_Met_Meta_PP PF01053.20 KKK44925.1 - 0.0055 15.3 0.0 0.011 14.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme tRNA_lig_kinase PF08303.11 KKK44925.1 - 0.038 14.1 0.7 0.077 13.1 0.7 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain AMP-binding PF00501.28 KKK44928.1 - 2e-54 184.8 0.0 2.5e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK44928.1 - 0.00011 23.2 0.0 0.00021 22.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdvA PF18822.1 KKK44929.1 - 0.0024 17.7 0.9 0.0024 17.7 0.9 4.9 3 1 1 4 4 4 2 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 KKK44929.1 - 0.035 14.2 2.8 0.8 9.7 0.0 3.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps51 PF08700.11 KKK44929.1 - 0.097 12.8 4.0 1.1 9.4 0.3 3.4 3 0 0 3 3 3 0 Vps51/Vps67 Cnn_1N PF07989.11 KKK44929.1 - 4.3 7.6 11.8 0.39 10.9 0.3 3.9 4 1 0 4 4 4 0 Centrosomin N-terminal motif 1 HSBP1 PF06825.12 KKK44929.1 - 9.2 6.2 8.7 16 5.4 0.5 3.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 NAD_synthase PF02540.17 KKK44930.1 - 2.1e-70 236.6 0.0 2.4e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 KKK44930.1 - 2.5e-06 26.6 0.0 0.00017 20.5 0.0 2.4 2 1 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.21 KKK44930.1 - 0.0052 16.5 0.0 0.0074 16.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 KKK44930.1 - 0.0076 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC LRR_8 PF13855.6 KKK44932.1 - 1.6e-20 72.6 25.7 3.7e-11 42.6 6.3 2.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KKK44932.1 - 1.8e-09 37.7 13.0 2.7e-05 24.4 3.9 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK44932.1 - 0.0041 17.5 8.2 1.9 9.4 0.6 3.6 2 2 1 3 3 3 2 Leucine Rich Repeat TaqI_C PF12950.7 KKK44933.1 - 2.7e-09 37.1 9.7 2.7e-09 37.1 9.7 3.6 2 1 1 3 3 3 1 TaqI-like C-terminal specificity domain N6_Mtase PF02384.16 KKK44933.1 - 4.7e-09 35.9 6.0 2.6e-08 33.5 0.9 2.7 2 1 0 2 2 2 1 N-6 DNA Methylase Eco57I PF07669.11 KKK44933.1 - 1.2e-07 32.2 2.4 2.1e-07 31.4 0.1 2.8 3 0 0 3 3 3 1 Eco57I restriction-modification methylase DUF4365 PF14280.6 KKK44933.1 - 0.00012 22.0 1.1 0.00032 20.7 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4365) Methyltransf_23 PF13489.6 KKK44933.1 - 0.00084 19.2 0.0 0.0027 17.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Pyr_redox_2 PF07992.14 KKK44934.1 - 6.6e-47 160.1 0.0 8.7e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KKK44934.1 - 5.2e-21 75.0 0.2 5.3e-20 71.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KKK44934.1 - 8.9e-14 51.8 0.2 8.9e-14 51.8 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK44934.1 - 8.5e-08 31.8 0.0 1.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KKK44934.1 - 0.0058 16.5 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK44934.1 - 0.03 13.7 0.2 0.089 12.2 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KKK44934.1 - 0.037 14.2 0.2 7.4 6.9 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF5061 PF16587.5 KKK44934.1 - 0.086 12.9 0.1 0.3 11.1 0.0 1.9 2 1 0 2 2 2 0 17 kDa common-antigen outer membrane protein NAD_binding_7 PF13241.6 KKK44934.1 - 0.2 12.1 0.3 0.79 10.2 0.3 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding PAS_4 PF08448.10 KKK44935.1 - 2.1e-18 66.6 0.0 2.3e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 KKK44935.1 - 2.9e-16 60.0 2.1 1.3e-15 57.8 0.5 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KKK44935.1 - 2.5e-11 43.8 0.5 2.6e-05 24.4 0.0 3.0 2 1 0 2 2 2 2 PAS domain PAS_8 PF13188.7 KKK44935.1 - 3.4e-11 42.9 0.0 0.00018 21.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KKK44935.1 - 8.6e-11 41.8 0.0 3.8e-08 33.3 0.0 2.9 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 KKK44935.1 - 0.00057 19.7 2.1 0.0043 16.9 2.1 2.6 1 1 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KKK44935.1 - 0.00063 19.7 0.0 0.0027 17.7 0.0 2.1 2 1 0 2 2 2 1 Histidine kinase-like ATPase domain DUF2884 PF11101.8 KKK44935.1 - 0.0019 17.8 0.0 0.0054 16.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) HisKA PF00512.25 KKK44935.1 - 0.0088 16.1 0.2 0.025 14.6 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HBM PF16591.5 KKK44935.1 - 0.031 13.7 0.6 0.083 12.3 0.6 1.7 1 0 0 1 1 1 0 Helical bimodular sensor domain PAS_7 PF12860.7 KKK44935.1 - 0.039 14.1 1.5 5.9 7.1 0.0 4.0 5 0 0 5 5 5 0 PAS fold GAPES3 PF17154.4 KKK44935.1 - 0.093 12.7 1.3 4 7.4 0.2 3.1 3 1 1 4 4 4 0 Gammaproteobacterial periplasmic sensor domain DUF3023 PF11224.8 KKK44935.1 - 0.74 9.6 6.4 0.75 9.6 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3023) APG6_N PF17675.1 KKK44935.1 - 4.1 7.9 10.2 11 6.6 3.7 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 KKK44935.1 - 4.5 7.7 9.7 9.8 6.6 0.6 3.2 3 0 0 3 3 3 0 Centromere protein H (CENP-H) D5_N PF08706.11 KKK44935.1 - 6.3 7.0 6.7 1.8e+02 2.3 6.7 2.6 1 1 0 1 1 1 0 D5 N terminal like HATPase_c PF02518.26 KKK44936.1 - 6.6e-15 55.6 0.4 2.4e-14 53.8 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 KKK44936.1 - 1.7e-14 54.3 0.0 2.3e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain HATPase_c_5 PF14501.6 KKK44936.1 - 1.2e-05 25.1 0.7 9.1e-05 22.3 0.1 2.4 1 1 1 2 2 2 1 GHKL domain GAF PF01590.26 KKK44936.1 - 0.0083 16.8 0.0 0.013 16.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KKK44936.1 - 0.032 14.3 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Roc PF08477.13 KKK44939.1 - 1e-21 77.3 0.0 1.2e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK44939.1 - 1.5e-21 76.6 0.0 1.7e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KKK44939.1 - 2.1e-08 33.8 0.0 2.2e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK44939.1 - 7.8e-08 32.0 0.0 9.1e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK44939.1 - 0.007 16.4 0.0 0.0075 16.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KKK44939.1 - 0.012 14.8 0.3 0.57 9.3 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 KKK44939.1 - 0.03 13.8 0.0 0.035 13.6 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KKK44939.1 - 0.033 13.5 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KKK44939.1 - 0.06 13.1 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK44939.1 - 0.077 12.5 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region CsrA PF02599.16 KKK44939.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Global regulator protein family Nitroreductase PF00881.24 KKK44942.1 - 5.3e-21 75.4 0.0 6.4e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK44942.1 - 8.2e-08 32.1 0.2 0.00049 19.7 0.0 2.1 1 1 1 2 2 2 2 Putative TM nitroreductase Trigger_N PF05697.13 KKK44942.1 - 0.12 12.7 0.4 0.19 12.0 0.4 1.4 1 1 0 1 1 1 0 Bacterial trigger factor protein (TF) Coprogen_oxidas PF01218.18 KKK44942.1 - 0.17 10.5 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase URO-D PF01208.17 KKK44943.1 - 1.7e-26 93.2 0.0 3.9e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) Abhydrolase_1 PF00561.20 KKK44944.1 - 5.9e-22 78.5 0.0 2.5e-20 73.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK44944.1 - 4.5e-12 47.1 0.0 5.4e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK44944.1 - 2.2e-09 37.0 0.0 1e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK44944.1 - 0.0014 17.4 0.0 0.0044 15.8 0.0 1.7 2 0 0 2 2 2 1 Ndr family FGGY_C PF02782.16 KKK44945.1 - 4.2e-34 118.0 0.0 7.8e-34 117.1 0.0 1.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KKK44945.1 - 6.7e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain TFIIB PF00382.19 KKK44948.1 - 7.3e-16 58.0 0.4 1.1e-15 57.4 0.4 1.3 1 0 0 1 1 1 1 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KKK44948.1 - 7.6e-12 44.5 0.8 1.4e-11 43.7 0.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding ArfGap PF01412.18 KKK44948.1 - 0.0089 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf C1_1 PF00130.22 KKK44948.1 - 0.012 15.5 0.4 0.022 14.6 0.4 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRN7 PF11781.8 KKK44948.1 - 0.016 14.9 1.5 0.029 14.1 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 A2L_zn_ribbon PF08792.10 KKK44948.1 - 0.021 14.6 2.4 0.043 13.5 2.4 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain Nudix_N_2 PF14803.6 KKK44948.1 - 0.047 13.6 1.8 0.22 11.5 1.8 2.1 1 1 0 1 1 1 0 Nudix N-terminal AbfS_sensor PF18225.1 KKK44948.1 - 0.11 12.4 0.0 0.47 10.4 0.0 2.0 1 1 1 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain Gar1 PF04410.14 KKK44949.1 - 5.3e-08 32.8 0.1 5.4e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PRC PF05239.16 KKK44949.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 PRC-barrel domain Radical_SAM PF04055.21 KKK44950.1 - 4.5e-05 23.9 0.3 0.00012 22.5 0.3 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Pneumo_NS1 PF03438.13 KKK44950.1 - 0.0068 16.5 3.4 2 8.5 0.2 2.5 2 0 0 2 2 2 2 Pneumovirus NS1 protein DUF5591 PF17884.1 KKK44951.1 - 1e-45 155.3 0.4 2.6e-45 154.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5591) TGT PF01702.18 KKK44951.1 - 1.9e-09 37.1 0.3 5e-09 35.8 0.2 1.7 2 0 0 2 2 2 1 Queuine tRNA-ribosyltransferase PUA PF01472.20 KKK44951.1 - 5.7e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 PUA domain TGT_C2 PF14810.6 KKK44951.1 - 0.037 14.2 0.1 0.58 10.3 0.0 2.3 2 0 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase AsnC_trans_reg PF01037.21 KKK44952.1 - 3.2e-10 39.8 0.0 4.2e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain HTH_11 PF08279.12 KKK44952.1 - 9.9e-07 28.6 0.1 0.022 14.7 0.0 2.6 2 0 0 2 2 2 2 HTH domain HTH_24 PF13412.6 KKK44952.1 - 2.6e-06 26.9 1.2 0.48 10.0 0.1 3.5 3 0 0 3 3 3 3 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK44952.1 - 5.5e-05 22.9 0.2 2.4 8.1 1.1 3.4 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain AlbA_2 PF04326.14 KKK44952.1 - 0.0063 16.8 1.3 2.2 8.7 0.1 2.4 2 0 0 2 2 2 2 Putative DNA-binding domain HTH_AraC PF00165.23 KKK44952.1 - 0.011 15.8 0.5 0.08 13.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_20 PF12840.7 KKK44952.1 - 0.011 15.7 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Mga PF05043.13 KKK44952.1 - 0.013 16.1 2.4 0.4 11.3 0.3 2.9 2 0 0 2 2 2 0 Mga helix-turn-helix domain HxlR PF01638.17 KKK44952.1 - 0.031 14.1 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 HxlR-like helix-turn-helix MarR_2 PF12802.7 KKK44952.1 - 0.031 14.2 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_10 PF04967.12 KKK44952.1 - 0.032 14.0 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain HTH_Crp_2 PF13545.6 KKK44952.1 - 0.051 13.6 0.1 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_CodY PF08222.11 KKK44952.1 - 0.054 13.1 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 CodY helix-turn-helix domain AdoHcyase PF05221.17 KKK44953.1 - 6.4e-60 202.8 0.0 7.7e-37 127.0 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KKK44953.1 - 2.3e-46 157.8 0.5 7.6e-46 156.1 0.0 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KKK44953.1 - 4.8e-07 29.3 0.0 9.1e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KKK44953.1 - 9.6e-05 22.0 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KKK44953.1 - 0.0016 19.0 0.0 0.0055 17.3 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KKK44953.1 - 0.015 15.3 0.0 0.067 13.2 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SNF2_N PF00176.23 KKK44954.1 - 3.5e-57 193.7 0.1 7.3e-57 192.7 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF3670 PF12419.8 KKK44954.1 - 1.8e-19 70.0 0.0 3.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 Helicase protein Helicase_C PF00271.31 KKK44954.1 - 6.1e-17 62.0 0.1 8.3e-16 58.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK44954.1 - 2.4e-07 30.9 0.0 1e-06 28.8 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KKK44954.1 - 0.017 14.3 0.0 0.044 13.0 0.0 1.7 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 KKK44954.1 - 0.074 13.4 0.0 25 5.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KKK44954.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SWIM PF04434.17 KKK44955.1 - 7.9e-08 31.8 0.2 1.3e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 SWIM zinc finger ArsA_ATPase PF02374.15 KKK44956.1 - 3.8e-51 174.1 0.3 4.8e-51 173.8 0.3 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KKK44956.1 - 5.4e-09 36.2 1.3 1.2e-08 35.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KKK44956.1 - 1.2e-08 35.0 2.5 1.6e-06 28.2 0.4 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KKK44956.1 - 8.7e-06 25.4 0.3 4.5e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KKK44956.1 - 0.0097 15.4 0.1 0.031 13.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KKK44956.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Cep57_MT_bd PF06657.13 KKK44956.1 - 0.13 12.7 0.6 0.38 11.2 0.2 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Lig_C PF18330.1 KKK44956.1 - 0.2 11.7 1.4 1.3 9.1 1.4 2.2 1 1 0 1 1 1 0 Ligase Pab1020 C-terminal region Toprim_4 PF13662.6 KKK44957.1 - 2.1e-09 37.7 0.1 7.1e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 KKK44957.1 - 2.5e-05 24.6 0.0 6.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Toprim-like AF-4 PF05110.13 KKK44957.1 - 0.037 12.1 1.2 0.041 12.0 1.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Toprim PF01751.22 KKK44957.1 - 0.038 14.2 0.6 0.58 10.4 0.1 3.0 3 1 0 3 3 3 0 Toprim domain Crp PF00325.20 KKK44957.1 - 0.071 12.8 0.4 0.18 11.5 0.4 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family SRP54 PF00448.22 KKK44958.1 - 3e-70 235.9 0.8 5.3e-70 235.1 0.8 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KKK44958.1 - 3.8e-10 39.9 7.2 4.2e-10 39.7 4.8 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KKK44958.1 - 7.2e-07 29.1 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KKK44958.1 - 3e-06 27.7 2.9 1.2e-05 25.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KKK44958.1 - 2.6e-05 24.5 0.1 0.00014 22.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KKK44958.1 - 0.0001 22.4 1.5 0.00012 22.1 0.2 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KKK44958.1 - 0.00011 21.6 0.2 0.00029 20.2 0.2 1.7 1 1 1 2 2 2 1 Zeta toxin AAA_19 PF13245.6 KKK44958.1 - 0.00041 20.7 0.1 0.0008 19.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KKK44958.1 - 0.00053 20.4 0.6 0.0023 18.4 0.5 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KKK44958.1 - 0.0013 18.1 0.3 0.0021 17.3 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KKK44958.1 - 0.0014 18.4 1.0 0.0088 15.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF4417 PF14386.6 KKK44958.1 - 0.0023 17.6 0.1 0.2 11.2 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4417) Thymidylate_kin PF02223.17 KKK44958.1 - 0.003 17.3 1.8 0.043 13.5 0.1 2.7 2 1 0 2 2 2 1 Thymidylate kinase AAA_33 PF13671.6 KKK44958.1 - 0.0037 17.4 0.2 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain PPK2 PF03976.14 KKK44958.1 - 0.008 15.7 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) MobB PF03205.14 KKK44958.1 - 0.027 14.3 2.6 1.6 8.6 0.2 2.5 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 KKK44958.1 - 0.034 14.4 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK44958.1 - 0.036 14.5 0.0 0.081 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KKK44958.1 - 0.039 14.3 0.2 0.71 10.3 0.2 2.4 1 1 0 1 1 1 0 RNA helicase KdpD PF02702.17 KKK44958.1 - 0.06 12.8 0.1 0.06 12.8 0.1 1.7 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain SPOUT_MTase PF02590.17 KKK44958.1 - 0.085 12.8 0.1 0.25 11.3 0.1 1.8 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase APS_kinase PF01583.20 KKK44958.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Helicase_RecD PF05127.14 KKK44958.1 - 0.1 12.5 2.1 0.2 11.5 0.5 2.0 1 1 1 2 2 2 0 Helicase cobW PF02492.19 KKK44958.1 - 0.37 10.3 6.4 0.05 13.2 1.6 1.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KKK44958.1 - 0.4 10.7 2.3 0.46 10.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 KKK44958.1 - 1.1 9.3 7.0 0.83 9.6 3.8 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit YolD PF08863.10 KKK44958.1 - 1.8 8.7 7.3 0.59 10.2 1.6 2.6 2 1 1 3 3 3 0 YolD-like protein Prefoldin PF02996.17 KKK44959.1 - 4e-19 68.7 3.7 4.8e-19 68.4 3.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KKK44959.1 - 0.00022 21.2 4.1 0.00022 21.2 4.1 1.8 1 1 1 2 2 2 2 Prefoldin subunit Csm1_N PF18504.1 KKK44959.1 - 0.032 14.6 3.9 0.086 13.2 0.7 2.4 2 1 0 2 2 2 0 Csm1 N-terminal domain S6PP_C PF08472.10 KKK44959.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal V-SNARE_C PF12352.8 KKK44959.1 - 0.57 10.5 6.4 6.5 7.1 0.9 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Fib_alpha PF08702.10 KKK44959.1 - 2.4 8.3 8.8 0.73 10.0 2.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L18A PF01775.17 KKK44960.1 - 6.9e-06 26.2 0.8 8.9e-06 25.8 0.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A eIF-6 PF01912.18 KKK44961.1 - 4.6e-51 173.0 0.0 5.4e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 eIF-6 family Ribosomal_L31e PF01198.19 KKK44962.1 - 9.6e-09 35.4 0.5 2.4e-08 34.1 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L31e Fib_alpha PF08702.10 KKK44962.1 - 0.3 11.3 3.2 0.22 11.7 1.7 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3073 PF11273.8 KKK44962.1 - 0.41 11.4 2.2 0.78 10.5 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) Ribosomal_L39 PF00832.20 KKK44963.1 - 1.4e-12 47.1 9.0 1.8e-12 46.7 9.0 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein dsDNA_bind PF01984.20 KKK44964.1 - 1.6e-20 73.4 5.3 1.8e-20 73.2 5.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_S19e PF01090.19 KKK44965.1 - 2.8e-41 140.4 0.0 3.2e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e CRS1_YhbY PF01985.21 KKK44966.1 - 6.8e-10 39.0 0.8 8.5e-10 38.7 0.8 1.1 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Rpr2 PF04032.16 KKK44967.1 - 3.3e-17 62.5 0.3 4.2e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain EMG1 PF03587.14 KKK44968.1 - 2.3e-44 151.4 0.8 2.6e-44 151.2 0.8 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase NB-ARC PF00931.22 KKK44968.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain DUF3258 PF11646.8 KKK44968.1 - 0.11 12.6 0.3 0.28 11.4 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF3258 Radical_SAM PF04055.21 KKK44969.1 - 1.2e-08 35.6 0.0 2.7e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily SCAPER_N PF16501.5 KKK44969.1 - 0.083 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum Fer4_14 PF13394.6 KKK44969.1 - 0.095 12.8 0.0 0.34 11.1 0.0 2.0 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF4065 PF13274.6 KKK44969.1 - 0.2 12.5 2.6 0.39 11.6 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) DUF1848 PF08902.11 KKK44969.1 - 3.1 7.4 5.7 24 4.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) DNA_alkylation PF08713.11 KKK44970.1 - 8.9e-34 117.1 0.2 1e-33 116.8 0.2 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme T4-Gluco-transf PF09198.10 KKK44970.1 - 0.44 10.2 2.1 0.47 10.1 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase Beta-lactamase PF00144.24 KKK44971.1 - 2.7e-23 82.7 0.0 4.7e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase SCP2 PF02036.17 KKK44971.1 - 4.3e-08 33.6 0.0 7.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KKK44971.1 - 0.063 13.6 0.0 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal Peptidase_S11 PF00768.20 KKK44971.1 - 0.078 12.4 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase HAD_2 PF13419.6 KKK44972.1 - 2.4e-23 83.1 0.0 3e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK44972.1 - 2.2e-12 47.7 0.0 1.2e-11 45.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK44972.1 - 4e-05 23.6 0.0 6.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3289 PF11692.8 KKK44972.1 - 0.0011 18.7 0.0 0.0055 16.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3289) HAD PF12710.7 KKK44972.1 - 0.0047 17.4 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KKK44972.1 - 0.13 12.4 0.1 1.3 9.1 0.1 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Methyltransf_31 PF13847.6 KKK44973.1 - 1.3e-07 31.5 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK44973.1 - 3.6e-06 27.6 0.0 1e-05 26.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK44973.1 - 5.7e-06 26.3 0.0 9.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK44973.1 - 8.4e-06 26.4 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK44973.1 - 0.0016 19.1 0.0 0.005 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain IceA2 PF05862.11 KKK44973.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Helicobacter pylori IceA2 protein Methyltransf_9 PF08003.11 KKK44973.1 - 0.069 12.1 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) SPG48 PF14764.6 KKK44973.1 - 0.086 13.3 0.7 0.24 11.9 0.2 1.9 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking Baculo_IE-1 PF05290.11 KKK44974.1 - 0.024 14.6 0.4 0.026 14.5 0.4 1.0 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF87 PF01935.17 KKK44975.1 - 2.2e-08 34.5 0.0 2.2e-08 34.5 0.0 2.2 2 1 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KKK44975.1 - 4.9e-06 26.1 0.0 7.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family Tetraspanin PF00335.20 KKK44975.1 - 4.5e-05 23.3 2.7 0.0001 22.1 2.7 1.5 1 0 0 1 1 1 1 Tetraspanin family Wzy_C PF04932.15 KKK44975.1 - 0.00084 19.0 1.2 0.0018 17.9 1.2 1.5 1 0 0 1 1 1 1 O-Antigen ligase TrwB_AAD_bind PF10412.9 KKK44975.1 - 0.0022 17.0 0.0 0.0052 15.7 0.0 1.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KKK44975.1 - 0.0052 15.9 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF853 PF05872.12 KKK44975.1 - 0.0061 15.2 0.0 0.0098 14.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) ATPase PF06745.13 KKK44975.1 - 0.0072 15.7 1.8 0.0097 15.3 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 KKK44975.1 - 0.0076 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KKK44975.1 - 0.014 15.6 0.1 0.18 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF2207 PF09972.9 KKK44975.1 - 0.18 10.5 16.3 0.37 9.5 0.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) 7TM_GPCR_Sra PF02117.16 KKK44976.1 - 0.034 13.0 4.4 0.09 11.6 4.3 1.7 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sra EamA PF00892.20 KKK44977.1 - 9.1e-09 35.6 10.5 1.3e-08 35.1 10.5 1.2 1 0 0 1 1 1 1 EamA-like transporter family Methyltransf_11 PF08241.12 KKK44977.1 - 0.0075 16.9 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KKK44977.1 - 0.065 12.1 0.1 0.2 10.5 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.6 KKK44977.1 - 0.13 13.0 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S49 PF01343.18 KKK44978.1 - 0.29 11.1 2.4 2.4 8.1 0.4 2.2 1 1 1 2 2 2 0 Peptidase family S49 CpXC PF14353.6 KKK44978.1 - 0.4 10.7 2.5 1.3 9.1 2.5 1.9 1 1 0 1 1 1 0 CpXC protein GFO_IDH_MocA PF01408.22 KKK44980.1 - 8.5e-21 75.0 0.1 1.4e-20 74.3 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KKK44980.1 - 0.0027 17.7 0.0 0.0057 16.7 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 KKK44980.1 - 0.034 14.7 0.1 0.069 13.7 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_2 PF13347.6 KKK44981.1 - 1.3e-57 195.2 36.1 1.5e-57 195.1 36.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 KKK44981.1 - 6.9e-19 68.0 34.5 6.9e-19 68.0 34.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3087 PF11286.8 KKK44981.1 - 0.13 11.7 1.5 0.38 10.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) HSP20 PF00011.21 KKK44982.1 - 8.7e-12 45.1 11.2 3.5e-06 27.1 5.7 3.4 2 1 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KKK44982.1 - 0.00039 19.9 2.4 0.0014 18.1 2.4 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Vfa1 PF08432.10 KKK44982.1 - 0.00091 19.6 19.8 0.00091 19.6 19.8 2.2 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.8 KKK44982.1 - 0.0012 17.7 6.3 0.0012 17.7 6.3 1.8 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 KKK44982.1 - 0.017 15.6 10.0 0.017 15.6 10.0 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 KKK44982.1 - 0.17 10.6 6.7 0.23 10.2 6.7 1.2 1 0 0 1 1 1 0 Presenilin Folate_carrier PF01770.18 KKK44982.1 - 0.78 8.4 1.9 0.35 9.5 0.0 1.4 2 0 0 2 2 2 0 Reduced folate carrier Cellulose_synt PF03552.14 KKK44982.1 - 0.84 8.1 6.1 1.1 7.6 6.1 1.2 1 0 0 1 1 1 0 Cellulose synthase Coilin_N PF15862.5 KKK44982.1 - 2.6 7.9 28.2 0.03 14.1 17.1 2.2 2 0 0 2 2 2 0 Coilin N-terminus Zip PF02535.22 KKK44982.1 - 2.9 7.0 8.7 0.1 11.8 3.1 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2828 PF11443.8 KKK44982.1 - 3.5 5.6 15.7 0.42 8.6 11.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) zinc_ribbon_2 PF13240.6 KKK44983.1 - 5.1e-09 35.5 10.8 1.4e-07 31.0 4.1 1.7 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK44983.1 - 3.6e-07 29.3 2.7 5.7e-07 28.7 2.7 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK44983.1 - 0.00022 21.2 3.7 0.00052 20.0 3.7 1.6 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK44983.1 - 0.00057 20.6 2.2 0.00057 20.6 2.2 1.5 2 0 0 2 2 1 1 zinc-ribbon family zf-NADH-PPase PF09297.11 KKK44983.1 - 0.0021 17.7 0.8 0.19 11.4 0.1 2.4 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.12 KKK44983.1 - 0.0085 16.2 1.1 0.013 15.6 1.1 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RecR PF02132.15 KKK44983.1 - 0.02 14.4 0.8 0.045 13.3 0.8 1.6 1 0 0 1 1 1 0 RecR protein HTH_24 PF13412.6 KKK44983.1 - 0.033 13.7 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Nudix_N_2 PF14803.6 KKK44983.1 - 0.04 13.8 3.8 0.2 11.6 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal RIFIN PF02009.16 KKK44983.1 - 0.041 13.8 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 Rifin DUF3784 PF12650.7 KKK44983.1 - 0.047 13.9 2.3 0.072 13.3 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) HTH_36 PF13730.6 KKK44983.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NOB1_Zn_bind PF08772.11 KKK44983.1 - 0.096 12.9 1.7 0.19 11.9 1.7 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like PLATZ PF04640.14 KKK44983.1 - 0.11 13.1 0.9 0.26 12.0 0.9 1.6 1 0 0 1 1 1 0 PLATZ transcription factor HTH_43 PF09904.9 KKK44983.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix UPF0547 PF10571.9 KKK44983.1 - 2.2 8.4 5.6 16 5.7 5.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 Fer4 PF00037.27 KKK44985.1 - 1.6e-08 34.0 10.4 5.9e-05 22.7 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK44985.1 - 7.4e-08 32.9 5.2 0.0012 19.3 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK44985.1 - 1.8e-07 31.9 10.7 0.00083 20.3 2.0 2.6 2 1 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK44985.1 - 1e-06 28.8 6.3 0.00045 20.3 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK44985.1 - 6e-06 26.1 11.4 0.00074 19.5 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK44985.1 - 1.6e-05 25.0 21.8 0.00016 21.7 12.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Flavodoxin_5 PF12724.7 KKK44985.1 - 2e-05 24.9 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Fer4_8 PF13183.6 KKK44985.1 - 2.6e-05 24.6 5.0 0.0092 16.4 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK44985.1 - 3.3e-05 24.0 2.8 5.9e-05 23.2 2.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK44985.1 - 8.7e-05 22.4 10.5 0.0062 16.6 1.9 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK44985.1 - 9.5e-05 22.9 5.9 0.027 15.0 0.4 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK44985.1 - 0.00019 21.7 12.8 0.025 15.1 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK44985.1 - 0.00021 21.3 12.1 0.0018 18.3 12.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK44985.1 - 0.00092 20.0 3.4 0.0092 16.8 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain BRCA-2_helical PF09169.10 KKK44985.1 - 0.088 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 BRCA2, helical Fer4_13 PF13370.6 KKK44985.1 - 0.22 12.1 13.7 1.9 9.1 3.8 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KKK44985.1 - 0.87 10.7 14.8 4.5 8.4 3.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain NUDIX PF00293.28 KKK44986.1 - 1.3e-16 60.8 0.0 1.7e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NAPRTase PF04095.16 KKK44988.1 - 0.0066 16.1 0.2 0.0081 15.8 0.2 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family PIN PF01850.21 KKK44990.1 - 0.00059 20.3 0.1 0.00081 19.9 0.1 1.3 1 0 0 1 1 1 1 PIN domain VAPB_antitox PF02697.14 KKK44991.1 - 0.0011 19.7 6.6 0.057 14.2 6.6 2.2 1 1 0 1 1 1 1 Putative antitoxin DUF3924 PF13062.6 KKK44991.1 - 0.021 14.8 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) MarR PF01047.22 KKK44992.1 - 7.8e-19 67.4 0.3 1.4e-18 66.6 0.0 1.6 2 0 0 2 2 1 1 MarR family MarR_2 PF12802.7 KKK44992.1 - 9.3e-11 41.5 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 KKK44992.1 - 2.2e-09 37.7 0.1 3.6e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain FeoC PF09012.10 KKK44992.1 - 2.7e-05 24.2 0.4 0.00033 20.7 0.4 2.3 1 1 0 1 1 1 1 FeoC like transcriptional regulator HTH_24 PF13412.6 KKK44992.1 - 0.00013 21.5 0.3 0.00039 19.9 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 KKK44992.1 - 0.00013 21.7 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 HxlR-like helix-turn-helix TrmB PF01978.19 KKK44992.1 - 0.00027 20.7 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 KKK44992.1 - 0.00033 20.8 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 KKK44992.1 - 0.0008 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HSP33 PF01430.19 KKK44992.1 - 0.0064 15.9 0.1 0.0082 15.6 0.1 1.2 1 0 0 1 1 1 1 Hsp33 protein Penicillinase_R PF03965.16 KKK44992.1 - 0.0075 16.6 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 Penicillinase repressor HTH_11 PF08279.12 KKK44992.1 - 0.015 15.2 0.1 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 HTH domain HTH_Crp_2 PF13545.6 KKK44992.1 - 0.015 15.2 0.1 0.065 13.2 0.0 2.0 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 KKK44992.1 - 0.015 15.4 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain SgrR_N PF12793.7 KKK44992.1 - 0.022 15.0 0.1 0.045 14.0 0.1 1.6 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term B-block_TFIIIC PF04182.12 KKK44992.1 - 0.073 13.2 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_7 PF02796.15 KKK44992.1 - 0.14 12.3 0.0 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase 4HB_MCP_1 PF12729.7 KKK44993.1 - 0.079 12.5 1.4 0.14 11.7 1.4 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Phage_holin_3_6 PF07332.11 KKK44993.1 - 0.35 10.9 3.0 0.39 10.8 3.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 KKK44993.1 - 6.7 5.4 7.1 6.7 5.3 7.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RibD_C PF01872.17 KKK44994.1 - 7.1e-16 58.6 0.0 1.3e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain PHP PF02811.19 KKK44995.1 - 6.8e-17 62.3 0.4 2.1e-14 54.2 0.4 2.6 2 1 0 2 2 2 2 PHP domain PHP_C PF13263.6 KKK44995.1 - 0.00031 20.4 0.0 0.00079 19.1 0.0 1.7 1 0 0 1 1 1 1 PHP-associated JmjN PF02375.17 KKK44995.1 - 0.27 11.2 1.3 19 5.3 0.2 3.6 4 0 0 4 4 4 0 jmjN domain Response_reg PF00072.24 KKK44996.1 - 1.4e-23 83.2 0.1 2.9e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PADR1 PF08063.12 KKK44997.1 - 0.0028 17.4 6.1 0.005 16.6 5.6 1.6 1 1 0 1 1 1 1 PADR1 (NUC008) domain Lar_restr_allev PF14354.6 KKK44997.1 - 0.0076 16.6 1.3 0.0091 16.4 1.3 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 KKK44997.1 - 0.0082 15.6 2.1 0.021 14.3 0.5 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KKK44997.1 - 0.0088 16.1 2.4 0.22 11.7 0.1 2.2 2 0 0 2 2 2 1 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK44997.1 - 0.013 15.4 2.9 0.033 14.1 2.9 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-ISL3 PF14690.6 KKK44997.1 - 0.03 15.0 2.1 0.091 13.4 0.3 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.19 KKK44997.1 - 0.04 14.0 0.7 2.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 KKK44997.1 - 0.2 11.5 7.4 3.2 7.7 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-3CxxC PF13695.6 KKK44997.1 - 0.22 12.0 4.9 0.47 10.9 1.7 2.0 2 0 0 2 2 2 0 Zinc-binding domain NifU_N PF01592.16 KKK44998.1 - 7.6e-36 123.1 0.2 8.3e-36 123.0 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF4707 PF15806.5 KKK44998.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) SIS PF01380.22 KKK44999.1 - 0.015 15.2 0.0 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 SIS domain GTP_EFTU PF00009.27 KKK45003.1 - 1e-58 198.1 0.0 1.5e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKK45003.1 - 1e-10 41.8 0.2 2.7e-10 40.5 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK45003.1 - 3.6e-07 30.2 0.0 8.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK45003.1 - 0.017 14.6 0.1 0.086 12.3 0.0 2.1 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKK45003.1 - 0.028 14.4 0.8 1.2 9.1 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 KKK45003.1 - 0.053 13.6 1.1 4.7 7.2 0.1 2.9 2 1 1 3 3 3 0 Dynamin family Usp PF00582.26 KKK45006.1 - 2.2e-21 76.9 0.0 4.7e-21 75.8 0.0 1.5 1 1 0 1 1 1 1 Universal stress protein family DASH_Dad4 PF08650.10 KKK45006.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad4 Abhydrolase_1 PF00561.20 KKK45007.1 - 3.9e-29 102.1 0.0 1.3e-28 100.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK45007.1 - 4.6e-22 78.5 0.0 7.9e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK45007.1 - 1.2e-21 78.3 0.0 1.4e-21 78.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KKK45007.1 - 4.8e-07 28.8 0.0 8.3e-07 28.0 0.0 1.7 1 1 0 1 1 1 1 Ndr family BAAT_C PF08840.11 KKK45007.1 - 4.1e-06 26.9 0.0 1.4e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KKK45007.1 - 1.8e-05 24.4 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KKK45007.1 - 6.1e-05 23.1 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Ser_hydrolase PF06821.13 KKK45007.1 - 0.00027 20.8 0.0 0.39 10.5 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_5 PF12695.7 KKK45007.1 - 0.00037 20.3 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 KKK45007.1 - 0.0004 20.1 0.0 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.20 KKK45007.1 - 0.00094 18.9 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KKK45007.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.18 KKK45007.1 - 0.0037 16.8 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 KKK45007.1 - 0.0038 17.4 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 KKK45007.1 - 0.023 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 KKK45007.1 - 0.024 14.2 0.0 0.048 13.3 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF915 PF06028.11 KKK45007.1 - 0.032 13.6 0.1 0.054 12.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 KKK45007.1 - 0.053 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2048 PF09752.9 KKK45007.1 - 0.1 11.7 0.0 0.95 8.5 0.0 1.9 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Palm_thioest PF02089.15 KKK45007.1 - 0.21 11.4 0.0 0.44 10.3 0.0 1.7 1 1 0 1 1 1 0 Palmitoyl protein thioesterase ECH_1 PF00378.20 KKK45008.1 - 1.1e-45 156.0 0.0 1.2e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK45008.1 - 5.2e-15 55.8 0.0 7.8e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KKK45008.1 - 0.078 12.9 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Beta-lactamase PF00144.24 KKK45009.1 - 3.7e-29 102.0 0.0 4.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase ECH_1 PF00378.20 KKK45011.1 - 6.7e-19 68.2 0.1 7.6e-19 68.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK45011.1 - 5.1e-17 62.4 0.0 5.7e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fer4 PF00037.27 KKK45012.1 - 4.4e-13 48.4 15.3 2.1e-06 27.3 3.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK45012.1 - 2e-09 37.5 10.5 2e-09 37.5 10.5 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45012.1 - 9.8e-09 34.9 12.7 0.00042 20.3 2.0 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK45012.1 - 2.4e-07 31.2 20.9 4.4e-06 27.2 10.9 2.7 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45012.1 - 3e-07 30.5 10.6 3e-07 30.5 10.6 2.4 1 1 2 3 3 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK45012.1 - 1e-05 25.5 9.5 1e-05 25.5 9.5 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK45012.1 - 0.00014 22.5 2.7 0.00014 22.5 2.7 3.1 2 1 1 3 3 2 1 4Fe-4S single cluster domain Fer4_2 PF12797.7 KKK45012.1 - 0.00021 21.2 11.1 0.0026 17.8 2.0 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45012.1 - 0.00032 21.6 17.2 0.0026 18.7 0.6 3.6 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK45012.1 - 0.026 15.0 1.1 0.026 15.0 1.1 3.0 3 0 0 3 3 2 0 4Fe-4S binding domain TrmB PF01978.19 KKK45012.1 - 0.029 14.2 0.0 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB CvfB_WH PF17783.1 KKK45012.1 - 0.072 12.9 0.3 8.6 6.3 0.0 3.3 3 0 0 3 3 3 0 CvfB-like winged helix domain Fer4_22 PF17179.4 KKK45012.1 - 0.074 13.9 0.4 0.074 13.9 0.4 4.0 3 1 0 3 3 2 0 4Fe-4S dicluster domain VAPB_antitox PF02697.14 KKK45012.1 - 2 9.2 5.0 23 5.8 0.1 3.1 3 1 0 3 3 2 0 Putative antitoxin Polbeta PF18765.1 KKK45013.1 - 6.1e-09 35.9 0.3 8.7e-09 35.4 0.3 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK45013.1 - 8e-09 35.7 0.2 1e-08 35.3 0.2 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2660 PF10859.8 KKK45014.1 - 0.007 16.8 0.9 0.01 16.3 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2660) DUF3417 PF11897.8 KKK45014.1 - 0.068 13.6 0.0 0.077 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) MaoC_dehydratas PF01575.19 KKK45015.1 - 4e-27 94.2 0.0 6.7e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK45015.1 - 1.8e-08 34.6 0.0 2.1e-06 27.9 0.0 2.6 2 1 1 3 3 3 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KKK45016.1 - 5.2e-31 106.8 0.0 8.9e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK45016.1 - 8.1e-06 26.0 0.0 0.00087 19.4 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Nmad3 PF18754.1 KKK45016.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 MaoC_dehydratas PF01575.19 KKK45017.1 - 1.1e-29 102.5 0.0 2e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK45017.1 - 1.7e-07 31.4 0.0 0.00013 22.1 0.0 2.5 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Lactamase_B PF00753.27 KKK45018.1 - 1.3e-16 61.2 0.0 2.8e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK45018.1 - 2.7e-10 40.1 0.0 3.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UvrB_inter PF17757.1 KKK45018.1 - 0.04 14.1 0.4 2.1 8.6 0.1 2.8 3 0 0 3 3 3 0 UvrB interaction domain Lactamase_B PF00753.27 KKK45019.1 - 8.3e-17 61.8 0.0 1.2e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK45019.1 - 4.6e-07 29.5 0.1 6e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK45019.1 - 0.025 14.5 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 KKK45019.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain DUF5492 PF17596.2 KKK45019.1 - 0.12 12.7 0.5 0.29 11.5 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5492) adh_short PF00106.25 KKK45020.1 - 1.3e-35 122.7 2.9 2.2e-35 121.9 2.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK45020.1 - 7.1e-35 120.7 0.2 1.2e-34 119.9 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK45020.1 - 1.9e-15 57.2 1.0 3.9e-15 56.2 1.1 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KKK45021.1 - 1.9e-61 207.6 0.0 2.3e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK45021.1 - 6.8e-58 195.3 0.8 1.8e-57 194.0 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK45021.1 - 1.6e-13 51.0 0.1 2.1e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.15 KKK45021.1 - 0.0051 16.7 0.0 0.0083 16.0 0.0 1.5 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.6 KKK45021.1 - 0.031 14.7 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding OMPdecase PF00215.24 KKK45021.1 - 0.12 11.9 0.1 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Thiolase_C PF02803.18 KKK45022.1 - 1.5e-40 137.7 0.4 2.7e-40 136.8 0.4 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 KKK45022.1 - 3.2e-28 98.8 0.0 1.3e-24 87.0 0.0 2.9 3 0 0 3 3 3 2 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KKK45022.1 - 0.0043 16.7 0.1 0.43 10.1 0.0 2.9 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KKK45022.1 - 0.011 15.9 0.4 0.042 14.0 0.0 2.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CMD PF02627.20 KKK45023.1 - 1.4e-09 37.9 0.0 2.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Sigma70_r4 PF04545.16 KKK45023.1 - 0.0086 15.6 0.0 0.021 14.4 0.0 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 hSac2 PF12456.8 KKK45023.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 Inositol phosphatase CMD PF02627.20 KKK45024.1 - 4e-07 30.0 0.0 5.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Nitroreductase PF00881.24 KKK45028.1 - 9.1e-30 103.9 0.2 1.7e-14 54.3 0.1 2.0 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 KKK45028.1 - 7.4e-14 51.8 3.5 1.2e-12 47.9 3.5 2.8 1 1 0 1 1 1 1 Putative TM nitroreductase Xlink PF00193.17 KKK45028.1 - 0.044 14.2 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 Extracellular link domain PALP PF00291.25 KKK45029.1 - 1.3e-10 41.2 0.0 1.3e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyr_redox_2 PF07992.14 KKK45031.1 - 4.1e-30 105.0 0.4 5.9e-30 104.5 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KKK45031.1 - 2.8e-20 72.2 4.4 5.5e-20 71.2 4.4 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 KKK45031.1 - 2.3e-13 50.5 2.9 6.3e-06 26.7 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK45031.1 - 1.6e-11 44.1 0.3 6.1e-05 22.4 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK45031.1 - 8.7e-09 35.5 0.0 7.8e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK45031.1 - 5.1e-06 26.3 1.1 0.00017 21.3 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK45031.1 - 1.4e-05 24.5 0.2 0.00053 19.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 KKK45031.1 - 5e-05 22.7 0.2 0.18 11.2 0.0 2.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KKK45031.1 - 5.2e-05 22.8 0.2 0.0072 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK45031.1 - 6.9e-05 22.3 0.2 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KKK45031.1 - 8.4e-05 21.9 0.0 0.00092 18.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KKK45031.1 - 0.00047 19.4 0.0 0.025 13.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 KKK45031.1 - 0.0005 19.7 0.2 0.2 11.2 0.1 2.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 KKK45031.1 - 0.00053 20.0 0.0 0.035 14.1 0.0 2.5 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KKK45031.1 - 0.00072 19.6 0.1 1.9 8.5 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase PALP PF00291.25 KKK45031.1 - 0.00073 19.0 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme HI0933_like PF03486.14 KKK45031.1 - 0.001 17.9 0.2 0.027 13.2 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 KKK45031.1 - 0.001 19.4 1.6 0.42 11.1 0.2 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 KKK45031.1 - 0.005 16.2 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 KKK45031.1 - 0.0072 16.2 0.5 0.12 12.2 0.0 2.7 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KKK45031.1 - 0.0089 16.2 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 KKK45031.1 - 0.014 14.5 0.1 2.6 7.0 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A FMO-like PF00743.19 KKK45031.1 - 0.017 13.5 0.2 0.43 8.9 0.1 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.24 KKK45031.1 - 0.032 13.3 0.1 0.087 11.9 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain XdhC_C PF13478.6 KKK45031.1 - 0.033 14.7 0.0 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain HTH_24 PF13412.6 KKK45035.1 - 1.6e-09 37.2 0.0 1.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK45035.1 - 2.6e-07 30.4 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 KKK45035.1 - 5.5e-07 29.4 0.0 9.1e-07 28.6 0.0 1.4 1 1 1 2 2 2 1 Bacterial regulatory protein, arsR family MarR PF01047.22 KKK45035.1 - 0.0044 16.9 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 MarR family TFA2_Winged_2 PF18121.1 KKK45035.1 - 0.0057 16.3 0.1 0.0089 15.7 0.1 1.3 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 Fe_dep_repress PF01325.19 KKK45035.1 - 0.044 14.0 0.0 0.049 13.8 0.0 1.1 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 KKK45035.1 - 0.068 13.1 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 KKK45036.1 - 2.1e-12 46.7 0.2 3.3e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK45036.1 - 1.3e-11 43.9 0.2 2.8e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 KKK45036.1 - 5.2e-05 23.1 0.1 0.00022 21.1 0.0 1.9 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain MarR PF01047.22 KKK45036.1 - 0.0002 21.2 0.0 0.00049 20.0 0.0 1.6 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 KKK45036.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 KKK45036.1 - 0.0058 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 KKK45036.1 - 0.0064 16.3 0.0 0.03 14.2 0.0 2.1 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_Tnp_Tc3_2 PF01498.18 KKK45036.1 - 0.055 13.7 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Transposase HTH_Crp_2 PF13545.6 KKK45036.1 - 0.055 13.4 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 KKK45036.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 KKK45036.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain zinc_ribbon_2 PF13240.6 KKK45037.1 - 2.7e-06 26.9 5.7 1e-05 25.1 5.7 1.9 1 1 1 2 2 2 2 zinc-ribbon domain DZR PF12773.7 KKK45037.1 - 8.4e-06 25.7 0.6 1.2e-05 25.2 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KKK45037.1 - 5.7e-05 23.0 1.2 0.21 11.6 0.1 2.4 2 0 0 2 2 2 2 Nudix N-terminal zf-ribbon_3 PF13248.6 KKK45037.1 - 6.3e-05 22.2 5.2 0.22 11.0 0.5 2.3 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK45037.1 - 0.00011 22.9 0.5 0.00012 22.7 0.5 1.2 1 0 0 1 1 1 1 zinc-ribbon family zinc-ribbons_6 PF07191.12 KKK45037.1 - 0.00031 20.7 0.7 0.0004 20.3 0.7 1.2 1 0 0 1 1 1 1 zinc-ribbons Zn-ribbon_8 PF09723.10 KKK45037.1 - 0.0013 18.8 3.3 0.004 17.2 2.9 1.9 1 1 1 2 2 2 2 Zinc ribbon domain zf-FPG_IleRS PF06827.14 KKK45037.1 - 0.0017 18.2 1.2 0.29 11.0 0.4 2.2 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS YhfH PF14149.6 KKK45037.1 - 0.0019 18.2 2.7 0.65 10.0 0.3 2.5 1 1 1 2 2 2 2 YhfH-like protein TF_Zn_Ribbon PF08271.12 KKK45037.1 - 0.0021 17.5 8.7 0.045 13.3 3.7 2.2 1 1 1 2 2 2 2 TFIIB zinc-binding zf-RING_7 PF02591.15 KKK45037.1 - 0.0028 17.8 0.9 0.71 10.1 0.1 2.3 2 0 0 2 2 2 1 C4-type zinc ribbon domain DNA_ligase_ZBD PF03119.16 KKK45037.1 - 0.0031 17.5 2.4 0.41 10.7 0.5 2.3 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain HypA PF01155.19 KKK45037.1 - 0.0044 17.0 0.2 0.0044 17.0 0.2 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0547 PF10571.9 KKK45037.1 - 0.0058 16.7 0.5 0.94 9.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 zf-NADH-PPase PF09297.11 KKK45037.1 - 0.0091 15.6 3.1 1.2 8.8 3.5 2.2 1 1 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK45037.1 - 0.0094 15.9 1.2 0.014 15.3 1.2 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain NOB1_Zn_bind PF08772.11 KKK45037.1 - 0.014 15.6 4.3 0.73 10.0 0.4 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C4_Topoisom PF01396.19 KKK45037.1 - 0.014 15.1 4.1 1.7 8.5 0.4 2.4 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Cript PF10235.9 KKK45037.1 - 0.015 15.9 0.1 0.017 15.7 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT DUF1610 PF07754.11 KKK45037.1 - 0.018 15.0 6.3 0.076 13.0 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Flu_M2 PF00599.17 KKK45037.1 - 0.019 15.0 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M2) zinc_ribbon_9 PF14369.6 KKK45037.1 - 0.02 15.1 2.9 2 8.7 0.1 2.3 1 1 1 2 2 2 0 zinc-ribbon Zn_ribbon_SprT PF17283.2 KKK45037.1 - 0.021 14.7 0.3 3 7.8 0.0 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 KKK45037.1 - 0.025 14.2 2.3 0.29 10.8 0.2 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF1272 PF06906.11 KKK45037.1 - 0.029 14.5 1.9 0.051 13.7 1.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) RNA_POL_M_15KD PF02150.16 KKK45037.1 - 0.05 13.5 1.7 8.7 6.3 0.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit GFA PF04828.14 KKK45037.1 - 0.053 13.9 2.0 0.61 10.5 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_3 PF13920.6 KKK45037.1 - 0.057 13.3 0.6 0.092 12.6 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF35_N PF12172.8 KKK45037.1 - 0.072 13.0 0.8 12 5.8 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CoiA PF06054.11 KKK45037.1 - 0.079 12.1 2.1 0.7 9.0 0.2 2.0 1 1 1 2 2 2 0 Competence protein CoiA-like family DUF3827 PF12877.7 KKK45037.1 - 0.087 11.2 0.0 0.091 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) zf-LITAF-like PF10601.9 KKK45037.1 - 0.1 12.9 7.6 8.9 6.7 0.2 3.2 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain A2L_zn_ribbon PF08792.10 KKK45037.1 - 0.1 12.3 2.2 6.1 6.7 0.3 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Di19 PF05605.12 KKK45037.1 - 0.1 12.9 1.9 0.45 10.9 0.2 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2321 PF10083.9 KKK45037.1 - 0.1 12.2 1.0 0.17 11.5 1.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Cation_ATPase_C PF00689.21 KKK45037.1 - 0.14 11.8 2.1 0.18 11.5 2.1 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus zf-TFIIB PF13453.6 KKK45037.1 - 0.29 10.5 3.3 3 7.2 0.3 2.2 1 1 1 2 2 2 0 Transcription factor zinc-finger Cys_rich_CPXG PF14255.6 KKK45037.1 - 0.3 11.0 3.2 4.4 7.3 0.1 2.6 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-tcix PF14952.6 KKK45037.1 - 0.4 10.3 3.2 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Rad50_zn_hook PF04423.14 KKK45037.1 - 0.69 9.8 5.2 1.6 8.7 0.8 2.2 1 1 1 2 2 2 0 Rad50 zinc hook motif DUF3797 PF12677.7 KKK45037.1 - 1.2 9.1 5.6 3.9 7.5 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-IS66 PF13005.7 KKK45037.1 - 1.2 9.6 4.4 22 5.5 0.1 2.5 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf_Rg PF17915.1 KKK45037.1 - 1.8 8.0 5.6 5.2 6.6 0.8 2.2 1 1 1 2 2 2 0 Reverse gyrase zinc finger MFS_1 PF07690.16 KKK45038.1 - 3.7e-32 111.6 53.0 6.4e-17 61.5 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK45038.1 - 6.3e-07 28.6 7.9 6.3e-07 28.6 7.9 3.0 1 1 0 2 2 2 1 Sugar (and other) transporter DDDD PF10161.9 KKK45038.1 - 0.12 12.1 5.6 11 5.9 1.4 4.0 2 1 1 3 3 3 0 Putative mitochondrial precursor protein UL41A PF17591.2 KKK45038.1 - 0.14 12.2 0.0 0.14 12.2 0.0 3.0 4 0 0 4 4 4 0 Herpesvirus UL41A MFS_1_like PF12832.7 KKK45038.1 - 0.35 9.7 30.9 0.84 8.4 15.6 2.3 1 1 1 2 2 2 0 MFS_1 like family MFS_3 PF05977.13 KKK45038.1 - 1 7.6 18.6 4.1 5.7 0.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Methyltransf_25 PF13649.6 KKK45039.1 - 3.8e-07 30.7 0.0 5.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK45039.1 - 3.9e-06 26.8 0.0 4.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK45039.1 - 3.1e-05 24.5 0.0 4.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK45039.1 - 0.00032 21.4 0.0 0.00048 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KKK45039.1 - 0.0068 16.2 0.0 0.0077 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KKK45039.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KKK45039.1 - 0.033 13.7 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain YqfD PF06898.11 KKK45039.1 - 0.036 12.9 0.1 0.037 12.9 0.1 1.0 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD PLN_propep PF16485.5 KKK45039.1 - 0.17 11.6 0.1 0.31 10.8 0.1 1.4 1 0 0 1 1 1 0 Protealysin propeptide zf-piccolo PF05715.13 KKK45040.1 - 0.041 14.0 0.1 0.066 13.4 0.1 1.3 1 0 0 1 1 1 0 Piccolo Zn-finger Picorna_P3A PF06363.11 KKK45040.1 - 0.16 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Picornaviridae P3A protein RNA_POL_M_15KD PF02150.16 KKK45041.1 - 3.9e-10 39.4 5.0 5.3e-10 39.0 5.0 1.2 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 KKK45041.1 - 0.0012 19.1 1.3 0.0016 18.7 1.3 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zinc-ribbons_6 PF07191.12 KKK45041.1 - 0.0015 18.4 0.5 0.0019 18.1 0.5 1.2 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.7 KKK45041.1 - 0.0072 16.3 0.7 0.0089 16.0 0.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK45041.1 - 0.014 14.8 1.4 0.019 14.4 1.4 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zf-RRPl_C4 PF17026.5 KKK45041.1 - 0.028 14.5 0.4 0.028 14.5 0.4 1.1 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Auto_anti-p27 PF06677.12 KKK45041.1 - 0.033 14.3 1.9 0.049 13.8 1.9 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DpnI PF06044.12 KKK45041.1 - 0.07 12.8 0.8 0.08 12.6 0.8 1.2 1 0 0 1 1 1 0 Dam-replacing family TF_Zn_Ribbon PF08271.12 KKK45041.1 - 1.1 8.8 7.9 0.95 9.0 1.8 2.3 1 1 1 2 2 2 0 TFIIB zinc-binding COX2_TM PF02790.15 KKK45043.1 - 0.009 16.1 3.5 0.4 10.9 0.9 2.1 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, transmembrane domain PLDc_N PF13396.6 KKK45043.1 - 0.012 15.5 9.6 0.012 15.5 9.6 3.2 1 1 2 3 3 3 0 Phospholipase_D-nuclease N-terminal DUF1673 PF07895.11 KKK45043.1 - 0.022 14.5 1.4 0.033 13.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2062 PF09835.9 KKK45043.1 - 0.043 13.7 0.4 0.043 13.7 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Zip PF02535.22 KKK45043.1 - 0.06 12.6 2.6 0.045 13.0 1.0 1.5 1 1 1 2 2 2 0 ZIP Zinc transporter DUF3810 PF12725.7 KKK45043.1 - 0.67 9.2 2.5 0.75 9.1 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2207 PF09972.9 KKK45043.1 - 1.2 7.8 3.1 1.4 7.6 3.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3021 PF11457.8 KKK45043.1 - 2.2 8.6 12.4 0.98 9.8 6.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) TNFR_16_TM PF18422.1 KKK45043.1 - 3 7.9 6.7 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF2157 PF09925.9 KKK45043.1 - 3 7.6 8.0 6.5 6.5 3.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Phage_holin_2_4 PF16082.5 KKK45043.1 - 6.3 6.6 5.8 4.1 7.2 1.2 2.0 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like Mon1 PF03164.14 KKK45044.1 - 0.00075 18.7 0.2 0.00084 18.5 0.2 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Longin PF13774.6 KKK45044.1 - 0.00096 19.1 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain SRP-alpha_N PF04086.13 KKK45044.1 - 0.053 13.4 0.6 0.075 13.0 0.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Rab15_effector PF15208.6 KKK45044.1 - 0.062 12.6 0.2 0.1 11.9 0.2 1.2 1 1 0 1 1 1 0 Rab15 effector SAGA-Tad1 PF12767.7 KKK45044.1 - 0.16 11.7 0.1 0.23 11.1 0.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CMD PF02627.20 KKK45045.1 - 1.6e-12 47.3 0.0 2.2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PA26 PF04636.13 KKK45045.1 - 0.0015 17.6 0.0 0.0015 17.6 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Prenylcys_lyase PF07156.14 KKK45045.1 - 0.0037 16.4 0.0 0.0047 16.1 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase DehI PF10778.9 KKK45045.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI PadR PF03551.14 KKK45046.1 - 1.2e-09 37.9 0.2 1.8e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Ta0938 PF11494.8 KKK45046.1 - 0.00015 22.0 0.3 0.00025 21.3 0.3 1.4 1 0 0 1 1 1 1 Ta0938 zf-FCS PF06467.14 KKK45046.1 - 0.021 14.7 1.8 0.039 13.9 1.8 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HTH_27 PF13463.6 KKK45046.1 - 0.023 15.2 0.1 0.086 13.3 0.0 1.9 1 1 1 2 2 2 0 Winged helix DNA-binding domain Replic_Relax PF13814.6 KKK45046.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Replication-relaxation ATPase-cat_bd PF12156.8 KKK45046.1 - 0.35 11.6 5.5 0.21 12.3 3.2 1.9 2 1 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase LRR_8 PF13855.6 KKK45047.1 - 9.7e-16 57.3 29.8 1.2e-07 31.4 2.9 4.8 5 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 KKK45047.1 - 3.1e-09 36.9 48.2 1.1e-06 28.9 3.9 6.7 4 3 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KKK45047.1 - 0.0098 15.4 19.4 0.16 11.4 3.8 3.7 1 1 3 4 4 4 2 Leucine-rich repeat LRR_5 PF13306.6 KKK45047.1 - 0.014 15.3 2.6 0.052 13.5 0.1 2.5 1 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KKK45047.1 - 0.052 13.6 14.3 1.9 8.7 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_2 PF07723.13 KKK45047.1 - 0.1 13.3 1.0 39 5.1 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat PTS_2-RNA PF01885.16 KKK45047.1 - 0.1 12.6 0.2 17 5.4 0.0 2.5 2 1 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family LRR_1 PF00560.33 KKK45047.1 - 0.47 11.2 29.1 1.4 9.7 0.2 7.7 9 0 0 9 9 9 0 Leucine Rich Repeat HTH_24 PF13412.6 KKK45048.1 - 2.8e-12 46.0 0.1 4.5e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK45048.1 - 5.5e-10 38.9 0.0 9.1e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 KKK45048.1 - 0.0039 17.1 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KKK45048.1 - 0.0042 16.9 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 KKK45048.1 - 0.0045 16.8 0.1 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family AsnC_trans_reg PF01037.21 KKK45048.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain TrmB PF01978.19 KKK45048.1 - 0.027 14.3 0.0 0.7 9.8 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 KKK45048.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 KKK45048.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 HTH domain DUF2250 PF10007.9 KKK45048.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Latrotoxin_C PF15658.6 KKK45049.1 - 0.087 12.6 0.3 0.098 12.4 0.3 1.1 1 0 0 1 1 1 0 Latrotoxin C-terminal domain Haem_bd PF14376.6 KKK45051.1 - 0.024 14.6 0.1 0.028 14.4 0.1 1.1 1 0 0 1 1 1 0 Haem-binding domain UPF0154 PF03672.13 KKK45052.1 - 4.8 7.3 4.5 19 5.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) PYNP_C PF07831.13 KKK45055.1 - 1.7e-08 34.0 0.0 3.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain Fer4_12 PF13353.6 KKK45055.1 - 0.02 15.1 0.1 0.036 14.3 0.1 1.4 1 1 0 1 1 1 0 4Fe-4S single cluster domain Biotin_lipoyl_2 PF13533.6 KKK45055.1 - 0.026 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like DUF5449 PF17528.2 KKK45055.1 - 0.056 13.2 0.1 0.066 13.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5449) LRR_8 PF13855.6 KKK45056.1 - 3e-30 103.7 68.5 6.1e-08 32.3 7.8 8.1 4 3 4 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 KKK45056.1 - 3.5e-24 84.5 92.6 9.8e-07 29.0 5.3 8.9 2 1 11 13 13 13 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KKK45056.1 - 8.6e-10 38.4 24.3 0.00043 19.8 4.0 4.2 2 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KKK45056.1 - 7e-06 25.7 57.2 0.97 9.7 0.9 12.5 12 0 0 12 12 12 5 Leucine Rich repeat LRR_1 PF00560.33 KKK45056.1 - 1.8e-05 24.6 67.0 0.7 10.7 0.2 13.4 14 1 0 14 14 14 6 Leucine Rich Repeat HEAT_2 PF13646.6 KKK45056.1 - 0.016 15.6 0.1 0.65 10.4 0.1 2.4 1 1 1 2 2 2 0 HEAT repeats LRR_5 PF13306.6 KKK45056.1 - 0.035 14.1 12.4 0.094 12.7 0.2 4.0 2 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DNA_ligase_A_M PF01068.21 KKK45057.1 - 1.1e-51 175.4 0.6 1.8e-51 174.7 0.6 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KKK45057.1 - 1.4e-32 113.4 3.3 2.6e-32 112.5 3.3 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KKK45057.1 - 2.4e-18 66.5 0.0 4.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KKK45057.1 - 3.1e-05 24.4 0.3 6.9e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 RNA ligase DUF3895 PF13034.6 KKK45057.1 - 0.24 11.5 1.1 9.6 6.3 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3895) DpnII PF04556.12 KKK45058.1 - 0.029 13.7 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 DpnII restriction endonuclease HisG PF01634.18 KKK45059.1 - 8.3e-34 116.9 0.0 1.1e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KKK45059.1 - 4.7e-14 52.3 0.0 1.2e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain IL6 PF00489.17 KKK45059.1 - 0.21 11.1 2.7 7 6.2 0.7 2.4 1 1 1 2 2 2 0 Interleukin-6/G-CSF/MGF family Histidinol_dh PF00815.20 KKK45060.1 - 3e-158 527.2 0.0 3.4e-158 527.0 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF5497 PF17601.2 KKK45060.1 - 0.048 14.0 2.9 1.2 9.5 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5497) CLTH PF10607.9 KKK45060.1 - 0.43 10.5 3.1 0.29 11.0 0.7 1.9 2 1 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Nitroreductase PF00881.24 KKK45064.1 - 2.1e-18 67.0 0.0 2.2e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK45064.1 - 0.0028 17.2 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase Acetyltransf_3 PF13302.7 KKK45065.1 - 5e-20 72.6 0.0 6.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK45065.1 - 0.0022 18.2 0.0 0.0028 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KKK45065.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CPBP PF02517.16 KKK45066.1 - 7.4e-08 32.7 10.8 7.4e-08 32.7 10.8 3.1 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease PFL-like PF02901.15 KKK45068.1 - 6.3e-163 543.8 0.4 1.1e-161 539.7 0.4 1.9 1 1 0 1 1 1 1 Pyruvate formate lyase-like PIN PF01850.21 KKK45069.1 - 8.7e-14 52.1 0.1 9.8e-14 51.9 0.1 1.0 1 0 0 1 1 1 1 PIN domain PCP_red PF08369.10 KKK45069.1 - 0.067 13.4 0.6 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Helicase_C_2 PF13307.6 KKK45069.1 - 0.14 12.3 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Helicase C-terminal domain VAPB_antitox PF02697.14 KKK45070.1 - 0.0018 19.0 8.3 0.013 16.3 8.3 1.9 1 1 0 1 1 1 1 Putative antitoxin SHOCT PF09851.9 KKK45070.1 - 0.078 12.7 3.6 0.088 12.6 2.0 1.9 2 0 0 2 2 2 0 Short C-terminal domain Bacillus_HBL PF05791.11 KKK45071.1 - 0.0044 16.9 1.3 0.0044 16.9 1.3 1.9 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) 4HB_MCP_1 PF12729.7 KKK45071.1 - 0.016 14.8 1.7 0.016 14.8 1.7 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction UPF0167 PF03691.14 KKK45071.1 - 0.15 11.9 3.5 0.083 12.7 0.9 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) Ribosomal_S11 PF00411.19 KKK45074.1 - 5.6e-39 132.9 0.6 7.4e-39 132.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 S4 PF01479.25 KKK45075.1 - 6.1e-15 54.7 0.1 1.5e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KKK45075.1 - 0.0012 19.7 2.3 0.0065 17.4 1.9 2.1 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_S13 PF00416.22 KKK45076.1 - 8.7e-38 129.6 1.6 1e-37 129.4 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 KKK45076.1 - 0.0064 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif EcKinase PF02958.20 KKK45077.1 - 1.1e-25 90.6 0.6 7.2e-14 51.8 0.2 2.6 2 1 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 KKK45077.1 - 2.7e-07 30.7 0.0 6.7e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KKK45077.1 - 0.00046 19.2 0.1 0.21 10.4 0.1 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1679) tRNA-synt_2b PF00587.25 KKK45078.1 - 1.1e-32 113.4 0.8 1.7e-32 112.8 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KKK45078.1 - 1.4e-20 73.5 12.3 1.4e-20 73.5 12.3 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain RasGAP_C PF03836.15 KKK45078.1 - 0.013 15.7 3.4 0.053 13.7 3.3 2.1 1 1 0 1 1 1 0 RasGAP C-terminus LAGLIDADG_WhiA PF14527.6 KKK45078.1 - 0.027 14.5 2.3 0.048 13.7 0.0 2.6 3 1 1 4 4 4 0 WhiA LAGLIDADG-like domain Methyltrn_RNA_4 PF09936.9 KKK45078.1 - 0.32 10.8 2.1 0.4 10.5 0.7 1.8 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase AAA_11 PF13086.6 KKK45078.1 - 1.9 8.2 8.4 3.4 7.4 8.4 1.3 1 0 0 1 1 1 0 AAA domain GreA_GreB_N PF03449.15 KKK45078.1 - 2.2 8.5 8.8 0.87 9.8 5.0 2.4 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal DUF4337 PF14235.6 KKK45078.1 - 4.8 7.3 9.7 3.2 7.9 7.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FlxA PF14282.6 KKK45078.1 - 5.3 7.1 12.8 1.3 9.0 9.4 1.8 2 0 0 2 2 2 0 FlxA-like protein Spc7 PF08317.11 KKK45079.1 - 0.052 12.4 36.1 0.095 11.6 13.8 3.3 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF5481 PF17578.2 KKK45079.1 - 0.089 13.2 0.6 0.089 13.2 0.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5481) VasL PF12486.8 KKK45079.1 - 0.19 11.6 5.1 0.05 13.5 1.3 1.9 2 1 1 3 3 3 0 Type VI secretion system, EvfB, or VasL DUF4349 PF14257.6 KKK45079.1 - 0.27 10.6 3.7 0.38 10.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) ADIP PF11559.8 KKK45079.1 - 1.7 8.7 33.6 0.035 14.2 12.5 3.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding UPF0184 PF03670.13 KKK45079.1 - 2.2 8.7 9.0 15 6.1 0.1 3.7 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) CofC PF01983.16 KKK45080.1 - 1.1e-12 47.7 0.4 1.5e-12 47.2 0.4 1.1 1 0 0 1 1 1 1 Guanylyl transferase CofC like Ras PF00071.22 KKK45081.1 - 1.5e-38 131.9 0.9 5.1e-38 130.2 0.9 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KKK45081.1 - 6e-26 91.0 0.4 3.9e-25 88.4 0.1 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK45081.1 - 1.3e-11 44.3 0.2 3.9e-10 39.4 0.2 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KKK45081.1 - 0.00011 22.1 0.1 0.053 13.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KKK45081.1 - 0.0015 17.9 0.9 0.005 16.2 0.9 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KKK45081.1 - 0.0035 17.1 0.1 0.53 10.0 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KKK45081.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3656 PF12392.8 KKK45081.1 - 0.069 13.8 0.3 0.082 13.6 0.3 1.4 1 1 0 1 1 1 0 Collagenase AAA_22 PF13401.6 KKK45081.1 - 0.099 12.9 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF4250 PF14056.6 KKK45081.1 - 0.14 12.1 0.6 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) TrmB PF01978.19 KKK45082.1 - 6.8e-16 57.9 0.0 1.7e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 KKK45082.1 - 1e-05 25.0 0.2 3.1e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 KKK45082.1 - 7.1e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KKK45082.1 - 0.00016 21.5 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.6 KKK45082.1 - 0.0006 19.7 1.5 0.0025 17.8 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 KKK45082.1 - 0.0063 16.3 0.0 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain Regulator_TrmB PF11495.8 KKK45082.1 - 0.014 14.6 0.2 0.023 13.9 0.2 1.5 1 1 0 1 1 1 0 Archaeal transcriptional regulator TrmB TFIIE_alpha PF02002.17 KKK45082.1 - 0.025 14.4 1.7 0.65 9.9 0.1 2.7 2 1 0 2 2 2 0 TFIIE alpha subunit HTH_5 PF01022.20 KKK45082.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 KKK45082.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KKK45082.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix CBFD_NFYB_HMF PF00808.23 KKK45083.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSBP1 PF06825.12 KKK45087.1 - 0.13 12.1 2.9 0.71 9.8 2.8 1.9 1 1 0 1 1 1 0 Heat shock factor binding protein 1 ATP-sulfurylase PF01747.17 KKK45088.1 - 2.7e-83 278.6 0.0 3.5e-83 278.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KKK45088.1 - 4.5e-43 146.7 0.0 7.5e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Phage-A118_gp45 PF10653.9 KKK45091.1 - 0.04 13.9 0.0 0.047 13.7 0.0 1.4 1 1 0 1 1 1 0 Protein gp45 of Bacteriophage A118 Gtr1_RagA PF04670.12 KKK45093.1 - 2e-20 73.1 0.0 4.4e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK45093.1 - 2.5e-11 43.3 0.0 4.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK45093.1 - 2.5e-09 36.9 0.0 3.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KKK45093.1 - 5.2e-08 32.5 0.0 1.5e-06 27.8 0.0 2.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK45093.1 - 2.8e-05 24.3 0.0 7.5e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK45093.1 - 0.027 14.6 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase FrhB_FdhB_C PF04432.13 KKK45094.1 - 3.8e-37 127.5 0.0 8.3e-37 126.4 0.0 1.6 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK45094.1 - 1.6e-18 66.6 0.0 3.9e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Fer4_10 PF13237.6 KKK45094.1 - 1.1e-06 28.6 12.6 1.8e-06 28.0 10.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45094.1 - 2.6e-06 27.0 17.1 0.0033 17.2 4.2 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KKK45094.1 - 5.6e-06 26.5 9.6 0.011 16.2 1.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK45094.1 - 6.9e-06 26.1 11.1 1.7e-05 24.9 9.8 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45094.1 - 0.0001 22.2 12.5 0.032 14.3 1.8 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK45094.1 - 0.00014 22.3 10.2 0.15 12.6 1.4 2.8 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45094.1 - 0.00043 20.7 12.7 0.16 12.4 2.8 2.6 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45094.1 - 0.0044 17.6 15.7 0.51 11.0 4.4 3.2 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45094.1 - 0.011 15.8 22.5 0.026 14.6 4.3 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain SurE PF01975.17 KKK45094.1 - 0.024 14.4 0.0 0.063 13.1 0.0 1.7 2 0 0 2 2 2 0 Survival protein SurE Fer4_21 PF14697.6 KKK45094.1 - 0.2 11.8 17.7 0.19 11.9 14.4 2.5 2 1 0 2 2 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45094.1 - 3.1 8.8 21.4 2.9 8.9 5.3 3.6 3 1 3 6 6 5 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 KKK45094.1 - 5.3 7.3 10.3 39 4.5 10.3 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK45094.1 - 8.3 7.0 13.4 16 6.1 1.8 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF4386 PF14329.6 KKK45095.1 - 1.3e-25 90.5 7.6 1.5e-25 90.3 7.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) Polbeta PF18765.1 KKK45097.1 - 9.5e-14 51.3 0.2 2.2e-13 50.1 0.2 1.6 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK45097.1 - 1.5e-10 41.3 0.0 2.2e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 KKK45097.1 - 0.0033 17.4 0.0 0.0044 17.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase NT domain HA70_C PF17993.1 KKK45097.1 - 0.0075 16.3 0.5 0.011 15.8 0.5 1.3 1 0 0 1 1 1 1 Haemagglutinin 70 C-terminal domain PTSIIA_gutA PF03829.13 KKK45097.1 - 0.11 12.4 0.2 11 5.9 0.0 2.3 1 1 1 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component DEAD PF00270.29 KKK45099.1 - 4.1e-16 59.3 0.0 5.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Succ_CoA_lig PF13607.6 KKK45100.1 - 1.7e-22 79.7 0.0 2.5e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Flavodoxin_3 PF12641.7 KKK45103.1 - 5.2e-15 55.5 0.0 6.2e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.7 KKK45103.1 - 5.8e-12 46.1 0.0 8.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 KKK45103.1 - 0.00015 22.0 0.0 0.00044 20.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin TatD_DNase PF01026.21 KKK45104.1 - 8.9e-17 61.3 0.0 9.9e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase VPS28 PF03997.12 KKK45107.1 - 4.1e-06 26.6 0.5 4.5e-06 26.5 0.5 1.0 1 0 0 1 1 1 1 VPS28 protein NikR_C PF08753.11 KKK45108.1 - 6.3e-06 26.3 0.1 1.2e-05 25.4 0.0 1.5 2 0 0 2 2 2 1 NikR C terminal nickel binding domain RHH_1 PF01402.21 KKK45108.1 - 0.0048 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF3574 PF12098.8 KKK45108.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) Rotamase PF00639.21 KKK45109.1 - 4.8e-22 78.7 0.0 6.9e-22 78.2 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KKK45109.1 - 1e-20 74.4 0.0 1.5e-20 73.9 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KKK45109.1 - 3.7e-05 24.6 0.0 4.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Response_reg PF00072.24 KKK45110.1 - 1.9e-17 63.4 0.0 2.2e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 KKK45111.1 - 1.8e-26 92.2 0.4 4.1e-12 46.2 0.1 3.4 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 KKK45111.1 - 3.2e-23 82.0 8.1 2.1e-10 40.8 0.1 3.7 3 0 0 3 3 3 2 PAS domain HATPase_c PF02518.26 KKK45111.1 - 3.2e-20 72.7 0.3 3.2e-20 72.7 0.3 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 KKK45111.1 - 1e-14 54.5 0.2 5.5e-08 32.8 0.0 3.2 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 KKK45111.1 - 7.4e-14 51.5 1.0 7.4e-14 51.5 1.0 2.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 KKK45111.1 - 1.6e-09 37.8 0.0 1.3e-05 25.3 0.0 3.3 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KKK45111.1 - 2.6e-09 37.3 0.0 1.5e-07 31.6 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 KKK45111.1 - 1.5e-08 34.5 0.2 0.14 12.2 0.0 3.9 3 0 0 3 3 3 3 PAS domain SPC25 PF06703.11 KKK45111.1 - 0.078 12.8 5.1 0.044 13.6 0.8 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4231 PF14015.6 KKK45111.1 - 1 9.9 4.0 57 4.3 1.9 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF4231) HD PF01966.22 KKK45112.1 - 1.5e-07 31.6 0.1 3.2e-07 30.6 0.1 1.6 1 1 0 1 1 1 1 HD domain HD_assoc PF13286.6 KKK45112.1 - 1.5e-05 25.5 0.0 0.15 12.6 0.0 2.6 2 0 0 2 2 2 2 Phosphohydrolase-associated domain RNR_Alpha PF17975.1 KKK45112.1 - 0.078 13.5 0.4 0.41 11.2 0.0 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain DUF1178 PF06676.11 KKK45115.1 - 0.0045 17.4 0.7 0.09 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1178) Zn_Tnp_IS1595 PF12760.7 KKK45115.1 - 0.28 11.2 3.2 6 6.9 0.0 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain AAA PF00004.29 KKK45116.1 - 2.4e-13 50.6 0.2 2.4e-13 50.6 0.2 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KKK45116.1 - 1.2e-12 47.9 2.5 1.2e-08 35.0 0.4 2.8 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KKK45116.1 - 2.9e-08 34.0 0.3 1.3e-07 32.0 0.3 2.2 1 0 0 1 1 1 1 Replication factor C C-terminal domain PhoH PF02562.16 KKK45116.1 - 2.2e-06 27.3 0.1 0.00071 19.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 KKK45116.1 - 5.5e-06 26.7 0.8 0.0043 17.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KKK45116.1 - 7.1e-06 26.1 0.5 2.3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KKK45116.1 - 9.8e-06 25.4 0.0 2.7e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 KKK45116.1 - 1.7e-05 24.7 2.0 0.0089 15.8 0.0 3.0 2 1 1 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KKK45116.1 - 5.7e-05 23.2 0.4 0.0023 18.0 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Rad17 PF03215.15 KKK45116.1 - 0.00014 21.9 0.1 0.00094 19.1 0.0 2.2 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KKK45116.1 - 0.00024 21.1 0.2 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK45116.1 - 0.00059 20.3 0.0 0.013 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 KKK45116.1 - 0.00076 18.9 0.2 0.17 11.2 0.0 2.6 1 1 2 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KKK45116.1 - 0.0018 18.8 0.1 0.0059 17.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KKK45116.1 - 0.0019 17.9 0.1 0.0071 16.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK45116.1 - 0.0031 17.1 0.0 0.0075 15.8 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 KKK45116.1 - 0.0041 16.2 0.0 0.0085 15.2 0.0 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KKK45116.1 - 0.0045 17.3 1.0 0.085 13.2 0.0 2.5 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.13 KKK45116.1 - 0.0078 15.4 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 KKK45116.1 - 0.008 16.5 0.0 0.028 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_11 PF13086.6 KKK45116.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KKK45116.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 KKK45116.1 - 0.015 15.0 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 KKK45116.1 - 0.027 13.7 0.6 0.099 11.9 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KKK45116.1 - 0.03 14.0 0.0 0.088 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KKK45116.1 - 0.033 14.6 0.0 0.14 12.5 0.0 2.1 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 KKK45116.1 - 0.043 13.7 0.1 1.5 8.7 0.0 2.7 2 1 0 2 2 2 0 NACHT domain TniB PF05621.11 KKK45116.1 - 0.052 13.0 0.3 1 8.7 0.0 2.7 2 1 1 3 3 3 0 Bacterial TniB protein PTPlike_phytase PF14566.6 KKK45116.1 - 0.11 12.6 0.1 3.5 7.7 0.0 2.4 1 1 1 2 2 2 0 Inositol hexakisphosphate DNA_pol3_delta2 PF13177.6 KKK45117.1 - 3.7e-08 33.3 0.1 2.7e-07 30.5 0.1 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 KKK45117.1 - 1.9e-07 31.4 0.4 2.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Replication factor C C-terminal domain RuvB_N PF05496.12 KKK45117.1 - 1.3e-05 25.0 0.0 0.00014 21.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KKK45117.1 - 1.5e-05 25.4 0.6 0.00052 20.4 0.1 3.1 2 2 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK45117.1 - 0.00033 20.9 0.1 0.16 12.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KKK45117.1 - 0.0018 18.2 2.8 0.022 14.7 0.6 2.5 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KKK45117.1 - 0.0021 18.5 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KKK45117.1 - 0.0038 17.0 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KKK45117.1 - 0.018 15.0 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 KKK45117.1 - 0.022 14.9 0.1 5.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 KKK45117.1 - 0.026 14.4 0.0 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 KKK45117.1 - 0.037 13.4 0.0 0.18 11.2 0.0 1.8 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KKK45117.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KKK45117.1 - 0.078 12.2 0.0 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 KKK45117.1 - 0.085 12.3 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KKK45117.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 KKK45117.1 - 0.15 11.8 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 KKK45118.1 - 9.5e-14 52.0 0.2 2.6e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KKK45118.1 - 2.7e-06 27.4 0.1 0.14 12.0 0.1 3.3 1 1 1 2 2 2 2 Rad17 P-loop domain AAA_5 PF07728.14 KKK45118.1 - 1e-05 25.6 0.2 0.00012 22.1 0.0 2.3 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KKK45118.1 - 1.4e-05 25.2 2.5 1.8e-05 24.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KKK45118.1 - 0.00011 22.5 0.0 0.0021 18.4 0.0 2.6 2 1 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 KKK45118.1 - 0.00018 21.3 0.0 0.00048 19.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KKK45118.1 - 0.00023 20.9 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKK45118.1 - 0.0013 19.1 0.0 0.04 14.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KKK45118.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KKK45118.1 - 0.0019 18.1 0.1 0.009 15.9 0.0 1.9 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KKK45118.1 - 0.0037 17.7 0.0 0.01 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 KKK45118.1 - 0.0047 16.7 0.0 0.0099 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KKK45118.1 - 0.0082 16.3 0.3 0.023 14.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KKK45118.1 - 0.0094 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK45118.1 - 0.011 16.2 0.0 0.031 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KKK45118.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KKK45118.1 - 0.031 14.0 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK45118.1 - 0.037 13.9 0.0 0.42 10.5 0.0 2.3 1 1 0 1 1 1 0 NACHT domain DNA_pol3_delta2 PF13177.6 KKK45118.1 - 0.038 13.8 0.0 0.13 12.0 0.0 2.0 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_33 PF13671.6 KKK45118.1 - 0.043 14.0 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KKK45118.1 - 0.067 12.9 0.9 0.2 11.3 0.0 2.1 2 1 0 2 2 2 0 Cytidylate kinase TsaE PF02367.17 KKK45118.1 - 0.083 12.9 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KKK45118.1 - 0.11 12.4 0.0 0.3 10.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KKK45118.1 - 0.14 12.4 0.1 0.73 10.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain RuBisCO_large PF00016.20 KKK45122.1 - 4.5e-57 193.5 0.0 9.4e-57 192.5 0.0 1.5 1 1 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RuBisCO_large_N PF02788.16 KKK45122.1 - 1.5e-08 34.8 0.0 5.4e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain Aminotran_1_2 PF00155.21 KKK45124.1 - 2e-44 152.3 0.0 2.4e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KKK45124.1 - 0.00062 18.7 0.0 0.00089 18.2 0.0 1.3 1 1 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 KKK45124.1 - 0.026 13.1 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RNase_Zc3h12a PF11977.8 KKK45124.1 - 0.035 13.9 0.0 0.12 12.2 0.0 1.9 2 1 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain DUF86 PF01934.17 KKK45127.1 - 1.1e-20 73.6 0.9 1.5e-20 73.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 Receptor_2B4 PF11465.8 KKK45127.1 - 0.0042 17.3 0.1 0.0069 16.6 0.1 1.4 1 1 0 1 1 1 1 Natural killer cell receptor 2B4 NTP_transf_2 PF01909.23 KKK45128.1 - 1.3e-13 51.1 0.8 1.5e-13 50.8 0.8 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KKK45128.1 - 1.5e-12 47.4 0.4 1.8e-12 47.1 0.4 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Radical_SAM PF04055.21 KKK45129.1 - 1.8e-17 64.2 0.0 3.3e-16 60.1 0.0 2.1 1 1 1 2 2 2 1 Radical SAM superfamily SPASM PF13186.6 KKK45129.1 - 6.7e-10 39.3 0.0 1.9e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 KKK45129.1 - 7.9e-10 39.1 0.0 1.7e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK45129.1 - 6.2e-09 36.0 0.1 1e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain PAC2 PF09754.9 KKK45129.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.5 1 1 0 1 1 1 0 PAC2 family Chrome_Resist PF09828.9 KKK45131.1 - 4.5e-15 56.3 1.0 4.8e-15 56.2 1.0 1.0 1 0 0 1 1 1 1 Chromate resistance exported protein VAPB_antitox PF02697.14 KKK45132.1 - 0.009 16.8 1.3 0.01 16.6 1.3 1.2 1 0 0 1 1 1 1 Putative antitoxin PIN PF01850.21 KKK45133.1 - 1.1e-10 42.1 0.2 1.3e-10 41.8 0.2 1.1 1 0 0 1 1 1 1 PIN domain DUF5615 PF18480.1 KKK45133.1 - 0.00056 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) Ras PF00071.22 KKK45134.1 - 4.1e-30 104.5 0.1 6.7e-30 103.8 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK45134.1 - 5.2e-19 68.6 0.0 4e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK45134.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK45134.1 - 0.0036 16.7 0.1 0.0054 16.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region IL3 PF02059.15 KKK45134.1 - 0.027 14.5 2.4 1.6 8.8 0.3 2.5 2 0 0 2 2 2 0 Interleukin-3 Med31 PF05669.12 KKK45134.1 - 0.081 12.9 0.4 31 4.7 0.0 3.3 4 0 0 4 4 4 0 SOH1 DNA_RNApol_7kD PF03604.13 KKK45134.1 - 0.48 10.1 2.0 12 5.7 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_7 PF02591.15 KKK45134.1 - 0.62 10.3 2.1 9.3 6.5 2.7 2.3 1 1 1 2 2 2 0 C4-type zinc ribbon domain Spore_II_R PF09551.10 KKK45135.1 - 0.055 13.9 0.5 0.093 13.2 0.5 1.3 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) UPF0489 PF12640.7 KKK45136.1 - 1.6e-15 57.8 0.3 1.6e-15 57.8 0.3 2.2 2 0 0 2 2 2 1 UPF0489 domain Spermine_synth PF01564.17 KKK45137.1 - 1.9e-34 118.7 0.2 3.3e-34 117.9 0.2 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KKK45137.1 - 8e-09 35.3 0.4 1.8e-08 34.2 0.4 1.7 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_30 PF05430.11 KKK45137.1 - 0.024 14.5 0.0 0.061 13.2 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 KKK45137.1 - 0.028 14.2 0.1 0.098 12.4 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF43 PF01861.16 KKK45138.1 - 9.6e-16 57.7 0.4 1.7e-15 56.9 0.4 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain N6-adenineMlase PF10237.9 KKK45138.1 - 0.00012 21.9 1.3 0.00028 20.7 1.3 1.6 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 KKK45138.1 - 0.00017 21.3 0.1 0.0004 20.1 0.1 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Med12 PF09497.10 KKK45138.1 - 0.0053 17.0 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Fer4 PF00037.27 KKK45139.1 - 5e-10 38.8 14.4 1e-06 28.3 3.6 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK45139.1 - 1e-08 35.1 10.6 1e-08 35.1 10.6 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45139.1 - 5.5e-07 30.1 21.4 0.00075 20.0 1.1 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45139.1 - 1e-06 28.8 11.7 1e-06 28.8 11.7 2.7 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45139.1 - 1.4e-06 28.1 10.3 0.0004 20.3 3.2 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK45139.1 - 2.4e-06 27.6 21.0 2.6e-05 24.2 11.8 2.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45139.1 - 4.1e-06 26.6 10.4 0.0006 19.7 1.8 3.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45139.1 - 9.9e-06 26.4 16.9 0.0043 17.9 1.4 3.7 2 1 1 3 3 3 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK45139.1 - 0.00042 20.6 1.9 0.00042 20.6 1.9 3.6 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_15 PF13459.6 KKK45139.1 - 0.02 15.6 1.2 0.02 15.6 1.2 3.5 3 1 1 4 4 3 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 KKK45139.1 - 0.024 15.2 26.0 0.044 14.3 1.5 3.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Dioxygenase_N PF04444.14 KKK45139.1 - 0.033 14.0 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Fer4_22 PF17179.4 KKK45139.1 - 0.036 14.9 7.0 0.093 13.6 1.1 4.1 3 1 1 4 4 4 0 4Fe-4S dicluster domain Phage_holin_6_1 PF09682.10 KKK45139.1 - 0.043 14.3 0.1 0.089 13.2 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Fer4_13 PF13370.6 KKK45139.1 - 0.056 14.0 1.8 0.056 14.0 1.8 3.6 3 1 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Ras PF00071.22 KKK45140.1 - 2e-43 147.8 0.5 2.4e-43 147.5 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK45140.1 - 4.2e-31 107.6 0.0 6.9e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK45140.1 - 8.1e-14 51.4 0.0 9.2e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK45140.1 - 1.5e-09 37.6 0.1 1.7e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KKK45140.1 - 3.2e-08 33.3 0.1 5.7e-07 29.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK45140.1 - 3.2e-05 23.5 0.0 5.6e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKK45140.1 - 0.00019 21.3 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK45140.1 - 0.0002 21.4 0.1 0.0004 20.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 KKK45140.1 - 0.00098 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KKK45140.1 - 0.0092 16.4 0.0 0.015 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KKK45140.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Septin PF00735.18 KKK45140.1 - 0.019 14.3 0.0 0.046 13.0 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 KKK45140.1 - 0.023 15.0 0.0 0.12 12.6 0.0 2.0 1 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KKK45140.1 - 0.036 13.9 0.1 2.1 8.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CoA_trans PF01144.23 KKK45141.1 - 1.3e-25 90.1 0.3 1.6e-25 89.8 0.3 1.1 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 KKK45142.1 - 1.2e-20 73.8 0.0 2e-20 73.1 0.0 1.3 1 1 0 1 1 1 1 Coenzyme A transferase MazE_antitoxin PF04014.18 KKK45143.1 - 0.07 13.1 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin PIN PF01850.21 KKK45144.1 - 1.6e-09 38.3 0.0 2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 PIN domain MOR2-PAG1_C PF14225.6 KKK45144.1 - 0.085 12.7 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Cell morphogenesis C-terminal PRiA4_ORF3 PF07929.11 KKK45145.1 - 7.3e-20 71.4 0.3 9.5e-20 71.0 0.3 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-SNAP50_C PF12251.8 KKK45145.1 - 2.7e-06 27.2 0.6 2.9e-06 27.1 0.6 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-UBR PF02207.20 KKK45145.1 - 0.016 15.4 5.3 0.027 14.6 5.3 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.7 KKK45145.1 - 0.049 13.7 3.9 0.085 12.9 3.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF4710 PF15828.5 KKK45145.1 - 0.14 12.3 2.9 0.24 11.5 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) zf-B_box PF00643.24 KKK45145.1 - 0.64 10.2 10.8 5.2 7.3 10.8 2.2 1 1 0 1 1 1 0 B-box zinc finger RibD_C PF01872.17 KKK45146.1 - 4.8e-15 55.9 0.0 9.7e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 RibD C-terminal domain PAS_3 PF08447.12 KKK45149.1 - 6.1e-36 122.6 0.0 1.8e-13 50.6 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 KKK45149.1 - 1.6e-30 105.4 2.9 2.4e-10 40.6 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 KKK45149.1 - 2.1e-27 95.3 0.0 2.2e-10 40.5 0.0 3.6 3 0 0 3 3 3 3 PAS fold HATPase_c PF02518.26 KKK45149.1 - 3.2e-24 85.6 4.7 7e-23 81.3 0.3 2.9 3 1 0 3 3 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KKK45149.1 - 3.4e-18 65.2 0.4 0.00012 22.0 0.1 3.6 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 KKK45149.1 - 1e-14 54.7 0.0 1.4e-05 25.3 0.0 3.4 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 KKK45149.1 - 4.1e-12 46.0 0.6 5e-10 39.3 0.1 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 KKK45149.1 - 2e-08 34.3 0.0 0.0038 17.3 0.0 3.9 2 1 2 4 4 4 2 PAS domain MEKHLA PF08670.11 KKK45149.1 - 0.0058 16.5 0.2 3.9 7.4 0.1 2.9 2 1 0 3 3 3 1 MEKHLA domain DUF1735 PF08522.10 KKK45149.1 - 0.0059 17.2 0.2 0.019 15.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1735) SirA PF10747.9 KKK45149.1 - 0.019 15.3 1.7 0.019 15.3 1.7 3.3 4 1 1 5 5 4 0 Sporulation inhibitor of replication protein SirA HATPase_c_5 PF14501.6 KKK45149.1 - 0.021 14.7 0.8 0.021 14.7 0.8 3.7 3 1 0 3 3 3 0 GHKL domain HATPase_c_2 PF13581.6 KKK45149.1 - 0.023 14.7 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF3882 PF07066.11 KKK45149.1 - 0.023 14.8 0.2 0.27 11.3 0.0 2.6 2 0 0 2 2 2 0 Lactococcus phage M3 protein ZNRF_3_ecto PF18212.1 KKK45149.1 - 0.051 13.6 0.5 29 4.7 0.0 3.5 3 1 0 3 3 3 0 ZNRF-3 Ectodomain RAG1_imp_bd PF12560.8 KKK45149.1 - 0.052 13.1 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 RAG1 importin binding PAS_7 PF12860.7 KKK45149.1 - 0.062 13.5 1.9 0.72 10.0 0.1 3.6 3 2 0 3 3 3 0 PAS fold UvrA_inter PF17760.1 KKK45149.1 - 0.18 11.9 1.7 3.9 7.6 0.0 3.5 4 0 0 4 4 4 0 UvrA interaction domain Fer4_6 PF12837.7 KKK45150.1 - 3.9e-07 29.9 9.8 6e-05 22.9 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 KKK45150.1 - 1.9e-06 27.5 8.7 3.4e-05 23.4 2.3 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK45150.1 - 2e-06 27.9 11.3 2e-06 27.9 11.3 2.6 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK45150.1 - 0.00017 21.6 23.1 0.0021 18.2 13.0 2.9 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45150.1 - 0.00052 20.5 0.5 0.00052 20.5 0.5 3.0 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45150.1 - 0.0029 17.6 4.3 0.0029 17.6 4.3 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 KKK45150.1 - 0.0038 17.9 8.8 0.051 14.3 0.7 2.7 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_21 PF14697.6 KKK45150.1 - 0.012 15.7 0.7 0.012 15.7 0.7 3.3 3 1 0 3 3 3 0 4Fe-4S dicluster domain HU-DNA_bdg PF14848.6 KKK45150.1 - 0.018 15.0 0.0 0.6 10.1 0.1 2.3 2 0 0 2 2 2 0 DNA-binding domain Fer4_16 PF13484.6 KKK45150.1 - 0.043 14.8 0.2 0.043 14.8 0.2 3.3 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK45150.1 - 0.043 14.3 2.8 0.043 14.3 2.8 3.8 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_8 PF13183.6 KKK45150.1 - 0.045 14.2 0.2 0.045 14.2 0.2 3.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain B5 PF03484.15 KKK45150.1 - 0.061 13.6 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase B5 domain PIN PF01850.21 KKK45151.1 - 0.00012 22.6 0.0 0.00015 22.3 0.0 1.1 1 0 0 1 1 1 1 PIN domain B12-binding PF02310.19 KKK45155.1 - 5.9e-20 71.5 0.1 1.1e-19 70.7 0.1 1.4 1 0 0 1 1 1 1 B12 binding domain B12-binding_2 PF02607.17 KKK45155.1 - 1.8e-09 37.9 0.2 4.1e-09 36.8 0.2 1.6 1 0 0 1 1 1 1 B12 binding domain URO-D PF01208.17 KKK45156.1 - 3.6e-32 111.9 0.0 2.3e-26 92.7 0.0 2.1 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) RuBisCO_small PF00101.20 KKK45156.1 - 0.023 14.7 0.5 14 5.7 0.0 3.3 3 0 0 3 3 3 0 Ribulose bisphosphate carboxylase, small chain Pput2613-deam PF14427.6 KKK45156.1 - 0.051 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Pput_2613-like deaminase DUF3179 PF11376.8 KKK45157.1 - 6.7e-24 84.7 0.0 1e-23 84.1 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3179) tRNA-synt_1 PF00133.22 KKK45158.1 - 1.1e-179 598.6 6.5 1.1e-179 598.6 6.5 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KKK45158.1 - 2.5e-26 92.5 3.4 2.5e-26 92.5 3.4 2.6 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KKK45158.1 - 3.6e-22 78.7 4.9 1.8e-10 40.2 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KKK45158.1 - 4.2e-06 26.3 0.6 0.00023 20.6 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DZR PF12773.7 KKK45158.1 - 0.28 11.2 3.0 61 3.8 0.0 3.4 2 1 0 2 2 2 0 Double zinc ribbon zf-C2HC5 PF06221.13 KKK45158.1 - 1.8 8.6 5.2 6.1 6.9 0.5 2.9 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type AAT PF03417.16 KKK45159.1 - 9.2e-33 113.8 0.0 1.5e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Aldo_ket_red PF00248.21 KKK45160.1 - 8.8e-77 258.2 0.0 9.9e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MerR_1 PF13411.6 KKK45160.1 - 0.07 13.2 0.0 0.27 11.3 0.0 2.0 1 0 0 1 1 1 0 MerR HTH family regulatory protein SMC_N PF02463.19 KKK45161.1 - 0.00097 18.6 0.1 0.0012 18.4 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 KKK45161.1 - 0.0024 18.4 0.1 0.0054 17.2 0.1 1.6 1 0 0 1 1 1 1 ABC transporter LRR_8 PF13855.6 KKK45165.1 - 1.9e-21 75.6 25.4 3.2e-10 39.6 7.2 4.6 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KKK45165.1 - 1.7e-16 60.0 28.4 7.9e-06 26.1 3.0 5.4 2 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KKK45165.1 - 9.5e-06 25.2 11.5 0.038 13.5 1.8 3.6 1 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 KKK45165.1 - 0.0002 21.5 19.7 17 6.4 0.2 8.2 8 0 0 8 8 8 1 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 KKK45165.1 - 0.0037 17.3 0.1 25 5.0 0.0 4.5 3 2 2 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain Corona_5a PF06336.11 KKK45165.1 - 0.042 13.8 0.1 0.099 12.6 0.1 1.6 1 0 0 1 1 1 0 Coronavirus 5a protein DUF5424 PF17462.2 KKK45165.1 - 0.15 12.0 0.5 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5424) KHA PF11834.8 KKK45165.1 - 0.19 11.8 0.6 9.7 6.4 0.0 3.0 3 0 0 3 3 3 0 KHA, dimerisation domain of potassium ion channel DUF1435 PF07256.12 KKK45165.1 - 0.22 11.6 3.4 0.16 12.1 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) LRR_2 PF07723.13 KKK45165.1 - 3.6 8.4 8.9 47 4.9 0.1 5.1 7 0 0 7 7 7 0 Leucine Rich Repeat NPV_P10 PF05531.12 KKK45166.1 - 0.0074 16.7 2.4 0.66 10.5 0.8 2.1 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KKK45166.1 - 0.0082 16.2 0.3 0.011 15.7 0.3 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_N PF02465.18 KKK45166.1 - 0.098 13.4 0.1 1.3 9.7 0.1 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus MscS_porin PF12795.7 KKK45166.1 - 0.13 11.8 0.2 0.18 11.3 0.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain IDH PF03971.14 KKK45166.1 - 0.14 10.5 0.2 0.17 10.3 0.2 1.0 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase FCH PF00611.23 KKK45167.1 - 0.05 13.9 1.8 0.14 12.4 1.8 1.8 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain HrcA_DNA-bdg PF03444.15 KKK45167.1 - 0.06 13.0 0.3 0.06 13.0 0.3 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DASH_Dad1 PF08649.10 KKK45167.1 - 0.13 12.5 1.1 28 5.0 0.0 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad1 BCDHK_Adom3 PF10436.9 KKK45167.1 - 0.26 11.1 3.9 0.4 10.5 0.2 2.1 1 1 1 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ANAPC15 PF15243.6 KKK45167.1 - 0.28 11.6 4.2 0.17 12.3 1.5 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF3450 PF11932.8 KKK45167.1 - 0.67 9.2 9.7 0.29 10.4 2.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 KKK45167.1 - 2 8.6 16.6 5.7 7.1 1.7 2.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 KKK45167.1 - 4.3 6.5 11.3 1.7 7.8 7.8 1.8 1 1 1 2 2 2 0 TMPIT-like protein GvpL_GvpF PF06386.11 KKK45167.1 - 4.5 7.1 7.0 2.6 7.9 0.6 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF1664 PF07889.12 KKK45167.1 - 6.2 6.9 10.9 11 6.0 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Radical_SAM PF04055.21 KKK45168.1 - 1.6e-21 77.4 0.1 4.5e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK45168.1 - 0.0015 18.8 0.3 0.0057 16.9 0.1 2.0 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK45168.1 - 0.0035 17.4 0.3 0.019 15.1 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain DUF1128 PF06569.11 KKK45168.1 - 0.065 13.2 0.2 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) TRAM PF01938.20 KKK45168.1 - 0.21 11.6 1.7 0.55 10.3 1.0 2.0 2 0 0 2 2 2 0 TRAM domain eRF1_1 PF03463.15 KKK45169.1 - 4.3e-29 101.1 1.9 9e-29 100.1 1.9 1.6 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KKK45169.1 - 2.2e-15 57.1 3.4 6.3e-15 55.6 1.0 2.5 2 1 0 2 2 2 1 eRF1 domain 3 eRF1_2 PF03464.15 KKK45169.1 - 3.9e-12 46.6 1.6 7.4e-12 45.7 0.5 1.9 2 0 0 2 2 2 1 eRF1 domain 2 baeRF_family10 PF18854.1 KKK45169.1 - 0.0073 16.6 0.0 0.061 13.6 0.0 2.3 3 0 0 3 3 3 1 Bacterial archaeo-eukaryotic release factor family 10 DUF4752 PF15944.5 KKK45169.1 - 0.039 14.0 0.1 0.3 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) NPM1-C PF16276.5 KKK45170.1 - 0.1 12.6 0.4 0.1 12.6 0.4 2.3 1 1 1 2 2 2 0 Nucleophosmin C-terminal domain Acetyltransf_1 PF00583.25 KKK45171.1 - 7.8e-15 55.1 0.0 9.6e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK45171.1 - 2.5e-10 40.4 0.1 3e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK45171.1 - 1.3e-08 35.1 0.1 1.9e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK45171.1 - 2.9e-07 30.4 0.0 5.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KKK45171.1 - 2.1e-05 25.2 0.1 0.00048 20.8 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KKK45171.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Fer4_14 PF13394.6 KKK45172.1 - 1e-08 35.3 0.4 2.6e-08 34.0 0.4 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK45172.1 - 8e-08 32.6 0.5 1.9e-07 31.4 0.5 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 KKK45172.1 - 2.4e-07 31.3 0.0 5e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily NTP_transf_2 PF01909.23 KKK45173.1 - 7.5e-06 26.2 0.1 1.7e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KKK45173.1 - 3.4e-05 23.8 0.0 7.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase CutA1 PF03091.15 KKK45175.1 - 4.1e-35 119.6 0.6 4.6e-35 119.4 0.6 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Glyco_hydro_2 PF00703.21 KKK45176.1 - 1.1e-11 45.4 1.9 2e-11 44.5 0.7 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KKK45176.1 - 2e-11 43.5 0.0 4.3e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KKK45176.1 - 9.5e-07 28.9 1.0 5.1e-06 26.5 0.2 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Mannosidase_ig PF17786.1 KKK45176.1 - 0.00017 22.1 0.0 0.00066 20.2 0.0 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain MgpC PF05220.12 KKK45176.1 - 0.11 11.8 0.1 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 MgpC protein precursor HTH_47 PF16221.5 KKK45177.1 - 0.00054 19.5 0.0 0.00096 18.7 0.0 1.4 1 0 0 1 1 1 1 winged helix-turn-helix TrmB PF01978.19 KKK45177.1 - 0.019 14.8 0.5 0.07 13.0 0.0 2.2 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 KKK45177.1 - 0.037 14.4 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 KKK45177.1 - 0.073 13.0 0.0 0.4 10.6 0.0 2.1 3 0 0 3 3 3 0 MarR family Longin PF13774.6 KKK45177.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 Regulated-SNARE-like domain CSN4_RPN5_eIF3a PF18420.1 KKK45177.1 - 0.11 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain Sterile PF03015.19 KKK45178.1 - 0.07 13.4 1.9 0.1 12.8 0.5 2.0 2 1 0 2 2 2 0 Male sterility protein RtcB PF01139.17 KKK45180.1 - 4.7e-137 457.5 0.0 5.4e-137 457.3 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB ORF6C PF10552.9 KKK45180.1 - 0.011 15.8 0.2 0.027 14.5 0.2 1.7 1 0 0 1 1 1 0 ORF6C domain DUF993 PF06187.11 KKK45180.1 - 0.061 12.2 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF993) DDE_Tnp_1 PF01609.21 KKK45182.1 - 0.00024 20.8 11.1 0.00024 20.8 6.4 2.6 2 1 0 2 2 2 1 Transposase DDE domain zf-SAP30 PF13866.6 KKK45182.1 - 0.097 12.8 0.1 5.7 7.1 0.1 2.8 2 0 0 2 2 2 0 SAP30 zinc-finger zinc_ribbon_2 PF13240.6 KKK45188.1 - 4.6e-05 23.0 0.4 7.3e-05 22.3 0.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK45188.1 - 0.00049 19.4 2.0 0.00078 18.8 2.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK45188.1 - 0.00049 20.1 1.0 0.00072 19.5 1.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KKK45188.1 - 0.013 15.4 0.9 0.57 10.2 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal DUF5337 PF17272.2 KKK45188.1 - 0.057 13.2 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DNA_RNApol_7kD PF03604.13 KKK45188.1 - 0.06 13.0 1.5 0.19 11.4 1.5 1.8 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_15 PF17032.5 KKK45188.1 - 0.14 12.9 1.2 0.34 11.7 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbon family zf-dskA_traR PF01258.17 KKK45188.1 - 0.2 11.6 3.2 0.89 9.6 0.2 2.2 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger zf_UBZ PF18439.1 KKK45188.1 - 0.23 11.1 0.8 11 5.7 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_13 PF18508.1 KKK45188.1 - 0.24 11.0 1.2 0.89 9.2 0.0 2.1 1 1 1 2 2 2 0 Zinc finger domain YtpI PF14007.6 KKK45188.1 - 0.25 11.5 0.4 0.25 11.5 0.4 2.9 2 1 1 3 3 3 0 YtpI-like protein SurA_N_3 PF13624.6 KKK45188.1 - 0.32 10.8 0.1 0.32 10.8 0.1 2.2 1 1 1 3 3 3 0 SurA N-terminal domain zf-ACC PF17848.1 KKK45188.1 - 0.55 10.3 3.0 2.2 8.4 0.2 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain AgrB PF04647.15 KKK45188.1 - 0.64 9.3 14.3 0.54 9.5 0.2 2.4 3 0 0 3 3 3 0 Accessory gene regulator B adh_short PF00106.25 KKK45189.1 - 3.4e-49 167.0 0.0 4.6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK45189.1 - 6.4e-38 130.6 0.0 7.7e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK45189.1 - 1.5e-09 38.0 0.0 2.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KKK45189.1 - 0.0066 17.1 0.0 0.039 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK45189.1 - 0.018 15.7 0.0 0.34 11.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KKK45189.1 - 0.045 13.3 0.0 9.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain DUF1776 PF08643.10 KKK45189.1 - 0.083 12.2 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Ldh_1_N PF00056.23 KKK45189.1 - 0.16 12.1 0.2 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KKK45189.1 - 0.16 11.9 0.6 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KKK45190.1 - 2.3e-43 147.9 0.0 3.3e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK45190.1 - 1.6e-35 122.8 0.0 3.7e-35 121.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK45190.1 - 3.5e-10 40.1 0.0 2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 KR domain HHH_5 PF14520.6 KKK45190.1 - 0.11 13.1 0.7 6.2 7.5 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain 3HCDH_N PF02737.18 KKK45190.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KKK45191.1 - 2.9e-08 33.4 0.8 3.1e-08 33.3 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK45191.1 - 4.1e-05 23.2 0.4 4.5e-05 23.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DFP PF04127.15 KKK45191.1 - 0.0048 16.7 0.0 0.0048 16.7 0.0 1.0 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 KKK45191.1 - 0.0098 15.3 0.2 0.0098 15.3 0.2 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KKK45191.1 - 0.026 15.1 0.4 0.029 15.0 0.4 1.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KKK45191.1 - 0.061 13.2 0.5 0.062 13.2 0.5 1.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Molybdopterin PF00384.22 KKK45193.1 - 3e-75 253.8 0.0 4e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 KKK45193.1 - 3.3e-12 46.2 0.3 5.4e-12 45.5 0.3 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain KGG PF10685.9 KKK45193.1 - 0.11 12.9 0.6 0.26 11.6 0.6 1.7 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif Arabinose_Isome PF02610.15 KKK45193.1 - 0.19 10.9 0.7 0.33 10.1 0.7 1.3 1 0 0 1 1 1 0 L-arabinose isomerase Ras PF00071.22 KKK45196.1 - 4.4e-29 101.2 0.0 4.9e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK45196.1 - 1.3e-13 51.2 0.0 2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK45196.1 - 1.1e-06 28.3 0.1 1.3e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Lactamase_B_2 PF12706.7 KKK45197.1 - 2.5e-12 46.8 0.0 3.2e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KKK45197.1 - 2.2e-05 24.4 0.0 4.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK45197.1 - 0.062 13.3 0.1 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily C1_1 PF00130.22 KKK45198.1 - 0.024 14.5 0.3 0.03 14.2 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L32p PF01783.23 KKK45198.1 - 0.063 13.5 0.5 0.59 10.4 0.1 2.0 1 1 1 2 2 2 0 Ribosomal L32p protein family ADK_lid PF05191.14 KKK45198.1 - 0.068 13.2 0.3 0.068 13.2 0.3 1.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid RNA_POL_M_15KD PF02150.16 KKK45198.1 - 0.22 11.4 2.7 0.46 10.4 2.7 1.7 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit EamA PF00892.20 KKK45199.1 - 3.5e-06 27.2 7.9 3.6e-06 27.2 7.9 1.0 1 0 0 1 1 1 1 EamA-like transporter family Rab5ip PF07019.12 KKK45199.1 - 0.16 12.6 4.8 0.19 12.4 4.8 1.1 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) RVT_1 PF00078.27 KKK45202.1 - 7.9e-47 159.6 0.0 1.9e-46 158.4 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_N PF13655.6 KKK45202.1 - 2.2e-30 104.7 1.2 4.1e-30 103.9 1.2 1.5 1 0 0 1 1 1 1 N-terminal domain of reverse transcriptase GIIM PF08388.11 KKK45202.1 - 1.8e-23 82.4 10.2 1.8e-23 82.4 10.2 2.2 2 0 0 2 2 2 1 Group II intron, maturase-specific domain Intron_maturas2 PF01348.21 KKK45202.1 - 0.011 15.7 1.4 0.02 14.9 1.4 1.5 1 0 0 1 1 1 0 Type II intron maturase ERCC4 PF02732.15 KKK45204.1 - 2.2e-20 73.5 0.1 3.9e-20 72.6 0.1 1.4 2 0 0 2 2 2 1 ERCC4 domain 5_3_exonuc PF01367.20 KKK45204.1 - 0.0036 17.9 0.2 0.0036 17.9 0.2 2.2 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 KKK45204.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HTH_5 PF01022.20 KKK45205.1 - 4.1e-07 29.8 1.6 4.1e-07 29.8 1.6 1.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KKK45205.1 - 1e-05 25.5 0.2 2.7e-05 24.2 0.1 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_34 PF13601.6 KKK45205.1 - 0.017 15.3 0.5 0.024 14.8 0.5 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain TBPIP PF07106.13 KKK45205.1 - 0.046 13.6 1.6 0.095 12.6 0.3 2.0 1 1 1 2 2 2 0 TBPIP/Hop2 winged helix domain MarR_2 PF12802.7 KKK45205.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 KKK45205.1 - 0.21 11.2 3.9 0.21 11.2 1.5 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Hit1_C PF18268.1 KKK45206.1 - 0.064 13.4 0.4 0.18 11.9 0.3 1.8 1 1 0 1 1 1 0 Hit1 C-terminal DUF2387 PF09526.10 KKK45207.1 - 0.0028 17.7 0.5 0.0034 17.5 0.5 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) DnaJ_CXXCXGXG PF00684.19 KKK45207.1 - 0.0069 16.7 0.4 0.0071 16.7 0.4 1.2 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KKK45207.1 - 0.055 13.4 0.2 0.056 13.4 0.2 1.2 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein HTH_33 PF13592.6 KKK45209.1 - 2.3e-18 65.5 0.4 5.1e-18 64.5 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.6 KKK45209.1 - 6.5e-10 38.9 0.0 2.2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 KKK45209.1 - 1.2e-08 34.5 0.0 6.4e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 KKK45209.1 - 1.6e-07 31.9 0.0 3.5e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 KKK45209.1 - 0.00011 22.3 0.0 0.00036 20.6 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KKK45209.1 - 0.051 13.2 0.4 0.22 11.2 0.2 2.2 2 1 0 2 2 2 0 Sigma-70, region 4 Terminase_5 PF06056.12 KKK45209.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) LZ_Tnp_IS481 PF13011.6 KKK45209.1 - 0.11 13.1 0.0 0.79 10.3 0.0 2.1 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 KKK45209.1 - 0.15 11.9 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain C_GCAxxG_C_C PF09719.10 KKK45212.1 - 2.1e-08 34.5 0.0 2.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) TPR_12 PF13424.6 KKK45213.1 - 9.8e-23 80.3 0.1 1.2e-07 31.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK45213.1 - 4.4e-11 42.0 4.9 0.051 13.7 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK45213.1 - 1e-10 40.9 17.9 0.028 14.2 0.1 7.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKK45213.1 - 6.4e-10 38.5 9.9 0.14 12.4 0.0 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK45213.1 - 3.6e-09 36.0 1.7 0.019 15.0 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KKK45213.1 - 4.3e-06 26.4 0.0 11 6.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK45213.1 - 9.3e-06 25.2 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 KKK45213.1 - 0.0031 18.1 0.0 4.8 7.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KKK45213.1 - 0.0056 16.3 2.1 12 5.7 0.1 4.7 5 1 1 6 6 6 0 TPR repeat TPR_6 PF13174.6 KKK45213.1 - 0.016 15.8 0.1 7 7.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 KKK45213.1 - 0.022 15.1 0.1 0.059 13.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKK45213.1 - 0.045 14.1 0.3 49 4.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KKK45213.1 - 0.059 13.6 2.7 87 3.7 0.0 4.4 5 0 0 5 5 4 0 PPR repeat ANAPC5 PF12862.7 KKK45213.1 - 0.065 13.3 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 ANAPC3 PF12895.7 KKK45213.1 - 0.29 11.4 0.1 0.29 11.4 0.1 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 HrcA_DNA-bdg PF03444.15 KKK45213.1 - 0.84 9.3 3.5 2.3 7.9 0.3 3.0 4 0 0 4 4 4 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding ECH_1 PF00378.20 KKK45214.1 - 8.5e-53 179.2 0.0 1e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK45214.1 - 1.9e-26 93.4 0.0 2.2e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NOB1_Zn_bind PF08772.11 KKK45215.1 - 0.0017 18.4 1.8 0.002 18.2 1.8 1.1 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 KKK45215.1 - 0.0021 18.0 0.9 0.0023 17.9 0.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-dskA_traR PF01258.17 KKK45215.1 - 0.0023 17.9 0.8 0.73 9.8 0.2 2.2 2 0 0 2 2 2 2 Prokaryotic dksA/traR C4-type zinc finger HypA PF01155.19 KKK45215.1 - 0.0051 16.8 0.6 0.0051 16.8 0.6 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 KKK45215.1 - 0.015 15.1 0.3 0.02 14.7 0.3 1.2 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Lar_restr_allev PF14354.6 KKK45215.1 - 0.018 15.4 1.3 0.3 11.5 0.1 2.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar NRDD PF13597.6 KKK45215.1 - 0.034 13.0 1.0 0.036 12.9 1.0 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Zn-ribbon_8 PF09723.10 KKK45215.1 - 0.036 14.2 5.1 0.077 13.1 5.1 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Ribosomal_L37e PF01907.19 KKK45215.1 - 0.049 13.8 3.0 0.061 13.5 3.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L37e PolC_DP2 PF03833.13 KKK45215.1 - 0.08 10.8 0.7 0.076 10.9 0.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Rubredoxin_2 PF18073.1 KKK45215.1 - 0.16 11.7 3.2 0.43 10.3 3.2 1.7 1 1 0 1 1 1 0 Rubredoxin metal binding domain zf_C2H2_13 PF18508.1 KKK45215.1 - 1.9 8.2 6.5 6.1 6.5 0.4 2.3 1 1 1 2 2 2 0 Zinc finger domain TPR_12 PF13424.6 KKK45216.1 - 2.2e-25 88.7 17.9 3e-05 24.2 0.1 6.2 4 2 4 8 8 8 7 Tetratricopeptide repeat SNAP PF14938.6 KKK45216.1 - 1.2e-14 54.4 16.6 5.5e-06 26.0 1.0 3.7 1 1 1 3 3 3 3 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 KKK45216.1 - 1.2e-11 43.8 30.4 5.7e-06 26.0 0.9 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KKK45216.1 - 2.4e-10 39.8 37.7 0.00033 20.6 1.3 7.6 6 1 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KKK45216.1 - 3.9e-09 36.0 34.5 3.6e-06 26.6 2.5 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat RPN7 PF10602.9 KKK45216.1 - 9.9e-07 28.6 14.3 0.0073 16.0 0.8 3.8 2 2 2 4 4 4 3 26S proteasome subunit RPN7 TPR_10 PF13374.6 KKK45216.1 - 1.8e-05 24.4 12.0 0.0047 16.8 0.4 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KKK45216.1 - 1.9e-05 24.3 16.9 0.13 12.4 0.4 6.8 7 2 0 7 7 6 2 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 KKK45216.1 - 0.00038 19.8 1.6 0.00066 19.0 1.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain TPR_MalT PF17874.1 KKK45216.1 - 0.00083 18.8 0.2 0.068 12.5 0.0 3.5 2 1 2 4 4 4 1 MalT-like TPR region DZR PF12773.7 KKK45216.1 - 0.0011 18.9 0.7 0.0022 18.0 0.7 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK45216.1 - 0.0024 17.5 4.6 0.0024 17.5 4.6 1.9 2 0 0 2 2 2 1 zinc-ribbon domain TPR_16 PF13432.6 KKK45216.1 - 0.0056 17.3 1.1 82 4.0 0.0 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK45216.1 - 0.016 16.0 2.0 50 5.1 0.0 5.3 6 1 1 7 7 6 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 KKK45216.1 - 0.044 13.6 1.2 0.084 12.7 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 KKK45216.1 - 0.12 12.4 1.4 3.6 7.6 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbons DUF2116 PF09889.9 KKK45216.1 - 0.14 12.1 0.4 0.3 11.1 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-LITAF-like PF10601.9 KKK45216.1 - 0.33 11.2 1.8 0.55 10.5 1.8 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain TPR_6 PF13174.6 KKK45216.1 - 0.39 11.5 19.2 17 6.3 0.1 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat zinc_ribbon_15 PF17032.5 KKK45216.1 - 0.47 11.2 4.8 0.89 10.3 4.1 1.9 2 0 0 2 2 1 0 zinc-ribbon family DUF2225 PF09986.9 KKK45216.1 - 3.7 7.2 34.0 1.1 8.9 9.7 5.2 2 2 3 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2225) Acetyltransf_1 PF00583.25 KKK45217.1 - 3.2e-05 24.1 0.0 4.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK45217.1 - 0.017 15.1 0.0 0.056 13.4 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK45217.1 - 0.027 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Caudo_bapla_RBP PF08931.10 KKK45217.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Receptor-binding protein of phage tail base-plate Siphoviridae, head FR47 PF08445.10 KKK45217.1 - 0.13 12.2 0.0 0.46 10.5 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein DUF3533 PF12051.8 KKK45217.1 - 0.23 10.3 0.1 0.39 9.6 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) LMP PF04778.12 KKK45218.1 - 0.0066 16.4 3.7 0.0066 16.4 3.7 2.5 3 0 0 3 3 3 1 LMP repeated region DUF2914 PF11141.8 KKK45218.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) DUF202 PF02656.15 KKK45219.1 - 0.12 12.8 0.0 0.12 12.8 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF202) ETRAMP PF09716.10 KKK45219.1 - 0.2 11.7 0.9 0.67 10.1 0.0 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TMCO5 PF14992.6 KKK45219.1 - 0.81 9.2 2.9 45 3.5 0.0 2.3 2 0 0 2 2 2 0 TMCO5 family HGTP_anticodon PF03129.20 KKK45220.1 - 5.4e-22 77.7 0.4 1.2e-21 76.7 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KKK45220.1 - 7.1e-12 45.7 0.1 3.7e-11 43.3 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zinc_ribbon_4 PF13717.6 KKK45220.1 - 0.016 15.1 1.5 6.3 6.8 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain tRNA-synt_2 PF00152.20 KKK45220.1 - 0.017 14.2 1.3 4.7 6.2 1.5 3.1 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) zinc_ribbon_15 PF17032.5 KKK45220.1 - 0.062 14.1 0.2 0.16 12.8 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK45220.1 - 0.33 10.4 1.2 29 4.3 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain MG2 PF01835.19 KKK45222.1 - 6.4e-05 23.3 0.0 0.0052 17.2 0.0 3.4 3 0 0 3 3 3 1 MG2 domain DUF4625 PF15418.6 KKK45222.1 - 0.00023 21.4 5.4 0.32 11.2 0.0 3.8 2 1 2 4 4 4 2 Domain of unknown function (DUF4625) Alph_Pro_TM PF09608.10 KKK45222.1 - 0.016 15.0 0.2 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) TcfC PF16967.5 KKK45222.1 - 0.023 14.2 1.8 0.61 9.6 0.0 3.1 3 0 0 3 3 3 0 E-set like domain DUF4064 PF13273.6 KKK45222.1 - 3.7 7.9 11.3 2.7 8.3 1.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) FTR_C PF02741.15 KKK45223.1 - 4.1e-61 205.4 0.2 5.8e-61 204.9 0.2 1.2 1 0 0 1 1 1 1 FTR, proximal lobe FTR PF01913.18 KKK45223.1 - 2.5e-51 173.4 0.0 3.6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Formylmethanofuran-tetrahydromethanopterin formyltransferase Asp4 PF16996.5 KKK45226.1 - 2.8 7.8 7.5 0.16 11.8 1.1 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 Inhibitor_I29 PF08246.12 KKK45227.1 - 0.045 14.2 0.1 0.051 14.0 0.1 1.1 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) PepSY_TM PF03929.16 KKK45228.1 - 0.16 11.6 2.5 0.22 11.1 2.5 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF3810 PF12725.7 KKK45228.1 - 2.5 7.4 7.3 3.5 6.9 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Thymidylate_kin PF02223.17 KKK45229.1 - 0.0031 17.2 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 Thymidylate kinase Zeta_toxin PF06414.12 KKK45229.1 - 0.017 14.4 0.0 0.043 13.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin UPF0180 PF03698.13 KKK45229.1 - 0.029 14.5 0.8 9.4 6.5 0.0 4.3 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0180) cobW PF02492.19 KKK45229.1 - 0.03 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PIN_2 PF10130.9 KKK45230.1 - 6.8e-25 87.8 0.6 8e-25 87.6 0.6 1.1 1 0 0 1 1 1 1 PIN domain PIN PF01850.21 KKK45230.1 - 7.1e-08 33.0 0.4 8.7e-08 32.7 0.4 1.1 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 KKK45230.1 - 0.00012 22.8 0.0 0.00017 22.4 0.0 1.2 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KKK45230.1 - 0.00048 20.7 7.8 0.0014 19.2 7.8 1.8 1 1 0 1 1 1 1 PIN domain PIN_4 PF13638.6 KKK45230.1 - 0.033 14.5 2.1 0.046 14.0 2.1 1.5 1 1 0 1 1 1 0 PIN domain AnfG_VnfG PF03139.15 KKK45230.1 - 0.047 13.8 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit CDC37_M PF08565.11 KKK45231.1 - 0.0085 16.0 0.1 0.0094 15.9 0.1 1.2 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain AFOR_C PF01314.18 KKK45232.1 - 6.2e-102 341.4 0.0 9e-102 340.9 0.0 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK45232.1 - 9.1e-48 162.8 0.0 1.5e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Pyr_redox_2 PF07992.14 KKK45233.1 - 3e-27 95.6 1.8 4.9e-27 94.9 1.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_4 PF13510.6 KKK45233.1 - 1e-17 64.0 0.0 1.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_BFD PF04324.15 KKK45233.1 - 8.1e-12 45.3 0.7 8.1e-12 45.3 0.7 2.7 3 0 0 3 3 2 1 BFD-like [2Fe-2S] binding domain NAD_binding_8 PF13450.6 KKK45233.1 - 1.4e-07 31.6 1.8 6.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KKK45233.1 - 1.5e-07 31.9 4.2 0.00012 22.6 0.3 3.5 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK45233.1 - 2.2e-07 30.4 0.7 4.9e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KKK45233.1 - 5.1e-06 25.4 8.8 1.9e-05 23.5 0.1 3.1 2 1 1 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KKK45233.1 - 3e-05 23.3 4.9 0.00018 20.7 0.0 2.7 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KKK45233.1 - 3.3e-05 23.3 1.9 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KKK45233.1 - 5e-05 22.8 5.6 0.00075 19.0 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KKK45233.1 - 8.1e-05 23.0 1.3 2.4 8.6 0.0 3.8 3 1 0 3 3 3 1 Putative NAD(P)-binding Fer4_21 PF14697.6 KKK45233.1 - 0.00024 21.2 10.2 0.00024 21.2 10.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45233.1 - 0.00052 20.5 7.3 0.00052 20.5 7.3 2.1 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45233.1 - 0.00059 19.9 8.7 0.00059 19.9 8.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45233.1 - 0.0013 18.4 4.7 0.0013 18.4 4.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain DAO PF01266.24 KKK45233.1 - 0.0027 17.4 5.0 0.35 10.4 2.6 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Fer4_4 PF12800.7 KKK45233.1 - 0.0042 17.5 1.1 0.0042 17.5 1.1 3.0 3 0 0 3 3 2 1 4Fe-4S binding domain GIDA PF01134.22 KKK45233.1 - 0.0049 16.0 2.4 0.44 9.6 0.0 3.0 4 0 0 4 4 4 1 Glucose inhibited division protein A Fer4_6 PF12837.7 KKK45233.1 - 0.0055 16.7 13.0 0.0088 16.1 3.0 2.8 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 KKK45233.1 - 0.0081 16.2 2.1 0.0081 16.2 2.1 3.3 4 0 0 4 4 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KKK45233.1 - 0.016 15.3 2.0 0.016 15.3 2.0 2.5 2 1 1 3 3 2 0 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 KKK45233.1 - 0.047 13.0 3.4 2.5 7.3 0.1 2.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_8 PF13183.6 KKK45233.1 - 0.052 14.0 5.9 0.071 13.6 0.1 2.9 3 0 0 3 3 2 0 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 KKK45233.1 - 0.07 12.4 11.2 0.078 12.2 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fer2_3 PF13085.6 KKK45233.1 - 0.11 12.5 0.3 0.35 10.9 0.3 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NAD_binding_9 PF13454.6 KKK45233.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KKK45233.1 - 0.13 11.2 0.1 0.28 10.2 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein InPase PF18823.1 KKK45233.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Inorganic Pyrophosphatase DAO PF01266.24 KKK45234.1 - 4.4e-52 177.8 0.0 5e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK45234.1 - 6.4e-06 25.1 0.2 0.0093 14.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 KKK45234.1 - 7.7e-05 22.1 0.6 0.0004 19.7 0.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK45234.1 - 9.7e-05 21.6 2.8 0.0026 16.9 0.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KKK45234.1 - 0.0001 21.7 0.5 0.23 10.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK45234.1 - 0.0017 17.8 0.2 0.015 14.7 0.4 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK45234.1 - 0.003 16.7 1.1 0.01 15.0 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KKK45234.1 - 0.0037 16.5 0.2 0.014 14.7 0.2 1.9 1 1 1 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KKK45234.1 - 0.045 13.0 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KKK45234.1 - 0.089 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M55 PF04951.13 KKK45234.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 D-aminopeptidase DASH_Dad4 PF08650.10 KKK45236.1 - 0.035 14.1 1.5 0.042 13.8 1.5 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 DUF848 PF05852.11 KKK45236.1 - 0.07 13.2 5.5 0.068 13.3 5.5 1.0 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) YtxH PF12732.7 KKK45236.1 - 0.1 13.2 4.6 0.12 13.0 4.6 1.1 1 0 0 1 1 1 0 YtxH-like protein NOG1_N PF17835.1 KKK45238.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.0 1 0 0 1 1 1 0 NOG1 N-terminal helical domain RHH_3 PF12651.7 KKK45239.1 - 0.00029 20.7 4.6 0.00031 20.7 0.5 2.2 2 1 0 2 2 2 1 Ribbon-helix-helix domain RHH_1 PF01402.21 KKK45239.1 - 0.087 12.8 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Bac_small_YrzI PF09501.10 KKK45241.1 - 0.093 12.9 2.3 0.15 12.2 2.0 1.5 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Malate_DH PF12434.8 KKK45241.1 - 4 7.5 5.5 3.1 7.9 0.6 2.3 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Exonuc_VII_S PF02609.16 KKK45242.1 - 0.074 13.1 0.0 7.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF4325 PF14213.6 KKK45243.1 - 4.2e-05 23.2 0.2 9.9e-05 22.0 0.2 1.8 1 1 0 1 1 1 1 STAS-like domain of unknown function (DUF4325) CAAD PF14159.6 KKK45243.1 - 0.13 12.2 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SpoIISB_antitox PF14185.6 KKK45243.1 - 0.14 12.1 0.3 0.14 12.1 0.3 1.9 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system HATPase_c PF02518.26 KKK45244.1 - 0.079 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KKK45244.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BatA PF07584.11 KKK45245.1 - 0.04 14.3 0.0 0.24 11.8 0.0 2.0 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal Phage_integrase PF00589.22 KKK45247.1 - 0.0024 17.7 0.1 0.036 13.9 0.1 2.6 1 1 0 1 1 1 1 Phage integrase family DNA_pol_alpha_N PF12254.8 KKK45247.1 - 0.014 15.5 0.2 0.07 13.2 0.2 2.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Phage_int_SAM_1 PF02899.17 KKK45247.1 - 0.094 13.0 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain OTCace PF00185.24 KKK45248.1 - 2.3e-49 167.5 0.1 4.2e-49 166.6 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 KKK45248.1 - 7.4e-45 152.6 0.0 1.3e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain TIR_2 PF13676.6 KKK45249.1 - 3.1e-08 34.2 0.1 9.8e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 TIR domain NACHT PF05729.12 KKK45249.1 - 3.8e-05 23.7 0.0 0.00016 21.7 0.0 2.0 2 1 0 2 2 2 1 NACHT domain KAP_NTPase PF07693.14 KKK45249.1 - 0.0067 15.7 0.0 0.021 14.1 0.0 1.7 1 1 1 2 2 2 1 KAP family P-loop domain DUF1863 PF08937.11 KKK45249.1 - 0.01 16.2 0.2 0.043 14.1 0.2 2.0 1 1 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) TIR PF01582.20 KKK45249.1 - 0.01 15.6 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 TIR domain AAA_22 PF13401.6 KKK45249.1 - 0.016 15.5 0.0 0.059 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK45249.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK45249.1 - 0.025 14.6 0.1 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Nuc_deoxyrib_tr PF05014.15 KKK45249.1 - 0.034 14.2 0.0 0.16 12.0 0.0 2.0 3 1 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase AAA_16 PF13191.6 KKK45249.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 KKK45249.1 - 0.15 11.7 0.0 0.55 9.8 0.0 2.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KKK45249.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KKK45249.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain TPR_2 PF07719.17 KKK45250.1 - 1.2e-10 40.6 7.7 0.0033 17.4 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat HTH_45 PF14947.6 KKK45250.1 - 6.8e-08 32.4 3.5 0.0044 17.0 0.0 3.8 3 0 0 3 3 3 2 Winged helix-turn-helix TPR_19 PF14559.6 KKK45250.1 - 1.7e-07 31.6 4.1 0.17 12.5 0.0 3.5 2 1 0 3 3 3 3 Tetratricopeptide repeat NARP1 PF12569.8 KKK45250.1 - 4.5e-07 29.1 6.4 3.5e-05 22.9 4.8 2.5 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KKK45250.1 - 5.7e-07 29.1 9.3 0.00051 19.7 0.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KKK45250.1 - 6.4e-07 29.6 4.5 4.2e-06 27.0 0.5 3.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KKK45250.1 - 3.1e-05 24.4 0.0 0.055 14.3 0.0 3.9 2 2 2 4 4 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KKK45250.1 - 0.0001 21.9 3.6 0.00013 21.5 2.3 1.8 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_8 PF13181.6 KKK45250.1 - 0.00014 21.8 14.8 0.02 15.1 0.3 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_34 PF13601.6 KKK45250.1 - 0.00086 19.4 0.7 2.9 8.1 0.0 3.5 3 2 0 3 3 2 2 Winged helix DNA-binding domain ANAPC3 PF12895.7 KKK45250.1 - 0.00087 19.5 4.0 0.27 11.5 0.3 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Mrr_N PF14338.6 KKK45250.1 - 0.0024 18.0 0.2 0.058 13.5 0.1 3.0 2 0 0 2 2 2 1 Mrr N-terminal domain TPR_6 PF13174.6 KKK45250.1 - 0.035 14.7 4.1 1.2e+02 3.7 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KKK45250.1 - 0.055 13.9 4.3 16 6.2 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MarR PF01047.22 KKK45250.1 - 0.057 13.3 0.0 0.23 11.4 0.0 2.0 1 0 0 1 1 1 0 MarR family TPR_7 PF13176.6 KKK45250.1 - 0.11 12.6 0.6 28 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 KKK45250.1 - 0.17 12.1 0.0 0.5 10.6 0.0 1.8 1 0 0 1 1 1 0 Tetratrico peptide repeat HTH_5 PF01022.20 KKK45250.1 - 0.29 11.0 1.7 4 7.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family TPR_11 PF13414.6 KKK45250.1 - 3.3 7.5 9.4 0.23 11.2 0.3 3.4 4 0 0 4 4 4 0 TPR repeat FR47 PF08445.10 KKK45251.1 - 1e-08 35.0 0.0 2.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KKK45251.1 - 1.2e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KKK45251.1 - 1.6e-06 28.3 0.0 2.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KKK45251.1 - 0.00014 22.6 0.0 0.00025 21.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KKK45251.1 - 0.00031 20.4 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 KKK45251.1 - 0.00052 20.1 0.0 0.0029 17.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK45251.1 - 0.0013 19.1 0.0 0.004 17.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PIN PF01850.21 KKK45252.1 - 2e-10 41.2 0.6 2.4e-10 41.0 0.6 1.1 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KKK45252.1 - 0.0015 19.0 3.8 0.0032 18.0 3.8 1.5 1 1 0 1 1 1 1 PIN domain Orbi_NS3 PF01616.16 KKK45252.1 - 0.035 13.8 0.1 0.041 13.6 0.1 1.1 1 0 0 1 1 1 0 Orbivirus NS3 MazE_antitoxin PF04014.18 KKK45253.1 - 4e-12 45.8 0.1 5.4e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PrlF_antitoxin PF15937.5 KKK45253.1 - 0.00039 20.8 0.1 0.00049 20.5 0.1 1.2 1 0 0 1 1 1 1 prlF antitoxin for toxin YhaV_toxin B3 PF02362.21 KKK45253.1 - 0.049 13.5 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 B3 DNA binding domain FliD_C PF07195.12 KKK45254.1 - 0.0029 17.1 0.1 0.0041 16.6 0.1 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus DUF2959 PF11172.8 KKK45254.1 - 0.034 14.3 0.6 0.062 13.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Hemagglutinin PF00509.18 KKK45254.1 - 0.04 12.3 0.0 0.056 11.8 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin DUF2884 PF11101.8 KKK45254.1 - 0.055 13.0 0.7 0.089 12.3 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) HSCB_C PF07743.13 KKK45254.1 - 4.4 7.9 8.8 2.2 8.8 0.5 3.4 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain Polbeta PF18765.1 KKK45255.1 - 2.7e-10 40.2 0.0 3.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK45255.1 - 1.9e-09 37.7 0.0 2.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Imm50 PF15594.6 KKK45255.1 - 0.075 13.3 0.1 2.3 8.5 0.1 2.2 1 1 0 1 1 1 0 Immunity protein 50 HEPN PF05168.14 KKK45256.1 - 1.9e-23 82.8 0.5 2.5e-23 82.5 0.5 1.1 1 0 0 1 1 1 1 HEPN domain Sec6 PF06046.13 KKK45256.1 - 0.011 14.2 0.6 0.012 14.0 0.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec6 SPATA24 PF15175.6 KKK45257.1 - 0.021 14.7 0.6 0.025 14.5 0.6 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 PIN PF01850.21 KKK45258.1 - 3.2e-07 30.9 0.0 5.4e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 PIN domain DUF5615 PF18480.1 KKK45260.1 - 5.8e-11 42.0 0.1 9e-11 41.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) PIN_10 PF18478.1 KKK45260.1 - 0.0022 18.1 0.0 0.0075 16.5 0.0 1.7 2 0 0 2 2 2 1 PIN like domain DUF2674 PF10879.8 KKK45260.1 - 0.065 12.8 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) Nore1-SARAH PF16517.5 KKK45260.1 - 0.26 11.2 0.6 0.26 11.2 0.6 1.8 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DUF433 PF04255.14 KKK45261.1 - 3.1e-24 84.6 0.0 4e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF433) MerR_2 PF13591.6 KKK45261.1 - 0.036 13.9 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_23 PF13384.6 KKK45261.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Rop-like PF05082.13 KKK45262.1 - 0.011 15.5 0.1 0.012 15.4 0.1 1.2 1 0 0 1 1 1 0 Rop-like RHH_1 PF01402.21 KKK45264.1 - 6.4e-09 35.4 0.7 1.2e-08 34.6 0.7 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family Sipho_tail PF05709.11 KKK45264.1 - 0.02 14.3 0.4 0.023 14.1 0.4 1.0 1 0 0 1 1 1 0 Phage tail protein LXG PF04740.12 KKK45264.1 - 0.024 14.4 0.3 0.027 14.2 0.3 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily MRVI1 PF05781.12 KKK45264.1 - 0.027 13.2 0.5 0.034 12.8 0.5 1.1 1 0 0 1 1 1 0 MRVI1 protein DUF5513 PF17632.2 KKK45264.1 - 0.03 14.7 0.1 0.04 14.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5513) DUF2240 PF09999.9 KKK45265.1 - 5.9e-05 22.7 0.2 7.2e-05 22.5 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2240) DUF1293 PF06950.11 KKK45265.1 - 0.028 14.5 0.2 0.043 14.0 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1293) BON PF04972.17 KKK45265.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 BON domain AA_kinase PF00696.28 KKK45266.1 - 9.5e-27 94.1 0.0 2.8e-26 92.6 0.0 1.6 1 1 0 1 1 1 1 Amino acid kinase family DUF86 PF01934.17 KKK45267.1 - 2.4e-21 75.8 1.1 3e-21 75.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 HEPN_Apea PF18739.1 KKK45267.1 - 0.01 16.3 1.3 0.02 15.3 1.2 1.6 1 1 0 1 1 1 0 Apea-like HEPN Pyridoxal_deC PF00282.19 KKK45267.1 - 0.049 12.3 0.2 0.062 12.0 0.2 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Polbeta PF18765.1 KKK45268.1 - 1.5e-13 50.6 0.8 1.8e-13 50.4 0.2 1.4 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK45268.1 - 1.6e-05 25.1 0.1 2.4e-05 24.5 0.1 1.4 1 1 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 KKK45268.1 - 0.049 13.5 0.0 0.09 12.7 0.0 1.4 1 1 0 1 1 1 0 Adenylate cyclase NT domain Abhydrolase_1 PF00561.20 KKK45269.1 - 3.2e-05 23.7 0.0 3.6e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK45269.1 - 0.00073 18.9 0.0 0.00082 18.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KKK45269.1 - 0.003 17.1 0.0 0.0036 16.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 KKK45269.1 - 0.0088 16.1 0.0 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 TAP-like protein PhoPQ_related PF10142.9 KKK45269.1 - 0.013 14.2 0.0 0.013 14.2 0.0 1.0 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Bac_luciferase PF00296.20 KKK45270.1 - 2e-48 165.4 0.0 3.8e-48 164.5 0.0 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase HTH_7 PF02796.15 KKK45271.1 - 0.16 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase ParE_toxin PF05016.15 KKK45272.1 - 1.6e-10 41.4 0.3 1.7e-10 41.3 0.3 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Rop-like PF05082.13 KKK45273.1 - 0.033 14.0 0.8 0.033 14.0 0.8 2.1 2 1 0 2 2 2 0 Rop-like CIDE-N PF02017.15 KKK45273.1 - 0.063 13.3 0.1 2.2 8.3 0.1 2.1 1 1 1 2 2 2 0 CIDE-N domain Aminotran_3 PF00202.21 KKK45274.1 - 1.1e-119 399.8 0.0 1.2e-119 399.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KKK45274.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II Polbeta PF18765.1 KKK45275.1 - 3.5e-07 30.2 0.4 8.2e-07 29.0 0.3 1.7 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK45275.1 - 2.1e-05 24.8 0.1 3.4e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain NTF-like PF14540.6 KKK45275.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase-like Acetyltransf_9 PF13527.7 KKK45278.1 - 0.00091 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4065 PF13274.6 KKK45278.1 - 0.12 13.3 3.6 0.16 12.9 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) Mad3_BUB1_II PF08171.11 KKK45279.1 - 0.063 13.5 1.1 0.15 12.2 1.1 1.6 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 zinc_ribbon_2 PF13240.6 KKK45280.1 - 2.3e-15 55.7 19.2 2.1e-08 33.6 4.9 3.2 3 0 0 3 3 3 2 zinc-ribbon domain DZR PF12773.7 KKK45280.1 - 5e-12 45.6 12.3 5e-12 45.6 12.3 1.6 2 0 0 2 2 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK45280.1 - 1.4e-10 40.2 12.4 4.6e-05 22.7 2.4 2.5 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK45280.1 - 2.1e-09 38.0 6.8 0.00056 20.6 1.7 2.4 2 0 0 2 2 2 2 zinc-ribbon family zf-NADH-PPase PF09297.11 KKK45280.1 - 6.4e-08 32.1 2.7 0.00018 21.1 0.4 2.6 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain UPF0547 PF10571.9 KKK45280.1 - 1.5e-05 25.0 13.2 0.0044 17.1 1.9 2.5 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.16 KKK45280.1 - 7.2e-05 22.6 1.7 7.2e-05 22.6 1.7 2.8 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit Ribosomal_L40e PF01020.17 KKK45280.1 - 0.012 15.5 1.0 0.012 15.5 1.0 1.7 1 1 0 1 1 1 0 Ribosomal L40e family NOB1_Zn_bind PF08772.11 KKK45280.1 - 0.012 15.7 12.6 0.1 12.8 1.6 2.6 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF1272 PF06906.11 KKK45280.1 - 0.012 15.7 0.9 0.012 15.7 0.9 3.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1272) TF_Zn_Ribbon PF08271.12 KKK45280.1 - 0.017 14.7 1.1 0.017 14.7 1.1 2.6 2 1 1 3 3 2 0 TFIIB zinc-binding HypA PF01155.19 KKK45280.1 - 0.047 13.7 10.7 0.38 10.8 1.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YhfH PF14149.6 KKK45280.1 - 0.054 13.5 13.8 0.1 12.6 2.5 3.6 1 1 2 3 3 3 0 YhfH-like protein zf-C3HC4_3 PF13920.6 KKK45280.1 - 0.059 13.2 8.3 0.46 10.4 0.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbon_6 PF10005.9 KKK45280.1 - 0.06 14.0 9.8 0.34 11.6 0.8 2.5 2 1 1 3 3 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 KKK45280.1 - 0.12 12.5 4.7 0.2 11.9 1.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF35_N PF12172.8 KKK45280.1 - 0.12 12.2 5.2 3.4 7.6 0.4 2.7 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Nudix_N_2 PF14803.6 KKK45280.1 - 0.13 12.2 0.2 0.13 12.2 0.2 3.6 4 0 0 4 4 3 0 Nudix N-terminal zf-tcix PF14952.6 KKK45280.1 - 0.22 11.2 8.4 0.48 10.1 2.4 2.9 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding PHF5 PF03660.14 KKK45280.1 - 0.32 11.2 6.2 0.27 11.5 4.8 1.6 2 0 0 2 2 1 0 PHF5-like protein DNA_ligase_ZBD PF03119.16 KKK45280.1 - 0.34 11.0 3.3 0.31 11.1 1.1 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 KKK45280.1 - 0.45 10.7 12.5 0.11 12.6 1.6 3.1 1 1 2 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK45280.1 - 0.65 10.0 10.5 0.074 13.0 1.9 2.7 1 1 2 3 3 3 0 Putative transposase DNA-binding domain zf-RING_7 PF02591.15 KKK45280.1 - 0.71 10.1 4.8 31 4.8 0.5 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain ADK_lid PF05191.14 KKK45280.1 - 0.79 9.8 9.0 2.6e+02 1.7 8.5 3.3 2 1 0 2 2 1 0 Adenylate kinase, active site lid GFA PF04828.14 KKK45280.1 - 0.83 10.0 8.7 0.81 10.1 0.3 3.2 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF2116 PF09889.9 KKK45280.1 - 1.1 9.3 8.4 2.4 8.2 1.2 2.4 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Cytochrom_c3_2 PF14537.6 KKK45280.1 - 1.2 9.6 9.1 5.1 7.6 9.1 1.8 1 1 0 1 1 1 0 Cytochrome c3 C1_1 PF00130.22 KKK45280.1 - 1.5 8.8 12.7 0.1 12.5 1.4 3.1 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DHHC PF01529.20 KKK45280.1 - 2.2 8.4 6.1 1.1 9.3 0.6 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf_UBZ PF18439.1 KKK45280.1 - 4.5 7.0 13.1 12 5.6 0.2 4.0 1 1 3 4 4 4 0 Ubiquitin-Binding Zinc Finger HscB_4_cys PF18256.1 KKK45280.1 - 6.1 6.8 15.8 0.28 11.1 4.0 2.8 2 1 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zf-C3HC4_4 PF15227.6 KKK45280.1 - 9.5 6.5 9.4 57 4.0 6.5 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING ABC_tran PF00005.27 KKK45282.1 - 2.1e-27 96.3 0.1 5.4e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KKK45282.1 - 8.3e-11 42.2 4.3 2.2e-06 27.7 0.5 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 KKK45282.1 - 5.4e-10 39.9 0.3 1.8e-09 38.2 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) Rad17 PF03215.15 KKK45282.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain STAS PF01740.21 KKK45282.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 STAS domain DUF4868 PF16162.5 KKK45282.1 - 0.059 13.3 1.9 0.34 10.8 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4868) AAA PF00004.29 KKK45282.1 - 0.07 13.5 0.2 0.21 12.0 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK45282.1 - 0.086 13.1 0.9 1 9.6 0.9 2.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KKK45282.1 - 0.096 12.4 0.1 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KKK45282.1 - 0.12 11.8 0.6 2.8 7.3 0.6 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KKK45283.1 - 2.3e-06 27.0 30.8 2.3e-06 27.0 30.8 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KKK45283.1 - 1.5e-05 24.4 27.1 6.2e-05 22.4 27.1 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KKK45283.1 - 0.001 19.1 12.8 0.001 19.1 12.8 2.5 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 KKK45283.1 - 0.0013 18.3 31.9 0.0031 17.1 31.9 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein Baculo_11_kDa PF06143.11 KKK45283.1 - 4.6 6.9 6.2 2 8.0 3.4 2.0 1 1 0 1 1 1 0 Baculovirus 11 kDa family CDP-OH_P_transf PF01066.21 KKK45284.1 - 1.1e-10 42.2 4.0 1.1e-10 42.2 4.0 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M32 PF02074.15 KKK45285.1 - 2.4e-170 567.5 0.5 2.8e-170 567.3 0.5 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase SieB PF14163.6 KKK45285.1 - 0.13 11.8 0.9 0.25 10.8 0.9 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B Arf PF00025.21 KKK45286.1 - 2.1e-11 43.6 0.2 4.4e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK45286.1 - 6.5e-09 36.1 0.0 1.7e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK45286.1 - 1.8e-08 34.2 0.0 5.2e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KKK45286.1 - 1.7e-07 31.3 0.7 0.025 14.5 0.3 2.5 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KKK45286.1 - 0.0058 16.1 0.0 0.0058 16.1 0.0 3.0 3 1 0 4 4 4 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KKK45286.1 - 0.011 15.4 2.0 0.13 12.0 0.0 3.1 2 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KKK45286.1 - 0.024 15.2 0.9 0.077 13.5 0.0 2.2 2 1 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 KKK45286.1 - 0.12 12.5 0.1 0.7 10.0 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cnd1 PF12717.7 KKK45288.1 - 8.4e-08 32.4 1.6 8.4e-08 32.4 1.6 2.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KKK45288.1 - 5.4e-05 23.5 0.5 0.017 15.5 0.0 2.5 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KKK45288.1 - 0.00013 21.9 0.1 12 6.5 0.0 3.6 3 0 0 3 3 3 3 HEAT repeat RTP1_C1 PF10363.9 KKK45288.1 - 0.00064 19.9 0.3 0.00064 19.9 0.3 2.8 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 MIF4G_like_2 PF09090.11 KKK45288.1 - 0.0022 17.5 1.0 0.0022 17.5 1.0 3.3 1 1 1 2 2 2 1 MIF4G like Longin PF13774.6 KKK45290.1 - 0.02 14.9 0.1 0.068 13.2 0.0 1.8 2 0 0 2 2 2 0 Regulated-SNARE-like domain GshA PF08886.11 KKK45291.1 - 3.3e-123 411.2 1.6 3.9e-123 411.0 1.6 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase ATPgrasp_YheCD PF14398.6 KKK45291.1 - 0.066 12.4 0.5 0.14 11.4 0.5 1.5 1 0 0 1 1 1 0 YheC/D like ATP-grasp GSH-S_ATP PF02955.16 KKK45292.1 - 6.8e-50 168.9 0.1 9.3e-50 168.4 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 KKK45292.1 - 1.1e-28 99.7 0.0 1.7e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 KKK45292.1 - 4.2e-13 49.3 0.0 6.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain TTL PF03133.15 KKK45292.1 - 0.0013 17.9 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KKK45292.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp DUF4446 PF14584.6 KKK45292.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) NIPSNAP PF07978.13 KKK45293.1 - 5.3e-05 23.4 0.0 0.0022 18.2 0.0 2.1 2 0 0 2 2 2 1 NIPSNAP UCR_Fe-S_N PF10399.9 KKK45293.1 - 0.085 12.2 0.3 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pyr_redox_2 PF07992.14 KKK45295.1 - 1.5e-08 34.2 0.0 1.8e-08 34.0 0.0 1.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK45295.1 - 3.7e-08 33.5 0.1 4.2e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK45295.1 - 2.2e-07 30.6 0.2 2.6e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK45295.1 - 8.7e-07 29.4 0.1 5.4e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK45295.1 - 5.8e-06 25.6 0.1 5.8e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKK45295.1 - 2.4e-05 23.8 0.4 3.1e-05 23.4 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KKK45295.1 - 3.3e-05 23.2 1.5 4e-05 22.9 1.5 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KKK45295.1 - 0.00019 21.1 1.4 0.00023 20.8 1.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KKK45295.1 - 0.0002 20.7 2.2 0.00059 19.2 1.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK45295.1 - 0.00023 20.0 1.5 0.00043 19.1 1.3 1.5 1 1 1 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KKK45295.1 - 0.00028 20.2 0.0 0.00028 20.2 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KKK45295.1 - 0.00066 19.0 0.1 0.00081 18.7 0.1 1.1 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 KKK45295.1 - 0.003 16.9 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KKK45295.1 - 0.01 14.9 0.1 0.01 14.9 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Staph_opine_DH PF10100.9 KKK45295.1 - 0.055 12.1 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase NAD_binding_9 PF13454.6 KKK45295.1 - 0.06 13.3 0.1 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KKK45295.1 - 0.068 12.0 0.1 0.074 11.9 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 KKK45295.1 - 0.1 11.3 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 MCRA family IlvN PF07991.12 KKK45295.1 - 0.13 11.8 0.3 0.16 11.5 0.2 1.3 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FrhB_FdhB_C PF04432.13 KKK45296.1 - 7.2e-33 113.6 0.1 7.2e-33 113.6 0.1 1.6 2 0 0 2 2 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK45296.1 - 3.8e-22 78.2 0.0 9.6e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Fer4_21 PF14697.6 KKK45296.1 - 3.5e-05 23.8 12.1 3.5e-05 23.8 12.1 1.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45296.1 - 0.00015 22.1 5.8 0.043 14.3 0.1 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45296.1 - 0.00034 20.7 16.7 0.0017 18.5 14.3 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45296.1 - 0.00081 19.4 15.3 0.015 15.4 2.7 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK45296.1 - 0.0014 19.2 13.3 0.0014 19.2 13.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45296.1 - 0.0021 18.1 2.4 0.0021 18.1 2.4 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KKK45296.1 - 0.0051 16.9 17.8 0.014 15.5 14.9 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45296.1 - 0.012 15.4 4.5 0.012 15.4 4.5 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK45296.1 - 0.019 15.5 16.7 0.5 11.0 3.7 3.3 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK45296.1 - 0.02 15.4 2.3 0.02 15.4 2.3 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK45296.1 - 3.3 8.6 11.6 6 7.8 0.9 3.1 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK45296.1 - 7.2 7.2 15.5 1.7 9.3 2.1 3.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I HTH_24 PF13412.6 KKK45298.1 - 6.1e-14 51.3 1.6 6.1e-14 51.3 1.6 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK45298.1 - 5e-12 45.5 0.4 9e-12 44.6 0.4 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KKK45298.1 - 1.5e-09 37.6 0.0 3.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_11 PF08279.12 KKK45298.1 - 3.3e-06 27.0 0.5 7e-06 25.9 0.5 1.6 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 KKK45298.1 - 9.5e-05 22.1 0.6 0.0002 21.0 0.6 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 KKK45298.1 - 0.0012 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 KKK45298.1 - 0.0067 16.3 0.3 0.016 15.1 0.1 1.7 2 0 0 2 2 2 1 MarR family Fer2_BFD PF04324.15 KKK45298.1 - 0.008 16.5 0.2 0.026 14.9 0.0 2.0 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Stk19 PF10494.9 KKK45298.1 - 0.016 14.9 0.5 0.018 14.7 0.5 1.1 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 MarR_2 PF12802.7 KKK45298.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 MarR family SprA_N PF14349.6 KKK45298.1 - 0.071 12.0 0.2 0.073 11.9 0.2 1.0 1 0 0 1 1 1 0 Motility related/secretion protein Fe_dep_repress PF01325.19 KKK45298.1 - 0.074 13.3 0.0 0.78 10.0 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_34 PF13601.6 KKK45298.1 - 0.078 13.2 0.1 0.12 12.6 0.1 1.4 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_23 PF13384.6 KKK45298.1 - 0.082 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_20 PF12840.7 KKK45298.1 - 0.089 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Radical_SAM PF04055.21 KKK45298.1 - 0.096 13.1 0.7 0.14 12.6 0.7 1.2 1 0 0 1 1 1 0 Radical SAM superfamily ACT_4 PF13291.6 KKK45298.1 - 0.099 13.2 2.8 0.34 11.5 0.1 2.7 2 1 1 3 3 3 0 ACT domain FeoC PF09012.10 KKK45298.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_Crp_2 PF13545.6 KKK45298.1 - 0.15 12.0 0.9 0.32 11.0 0.2 1.9 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain Ras PF00071.22 KKK45299.1 - 7.5e-44 149.2 0.0 8.6e-44 149.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK45299.1 - 7.4e-26 90.7 0.0 9.6e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK45299.1 - 1.4e-11 44.2 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KKK45299.1 - 4.4e-06 26.7 0.0 0.077 12.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KKK45299.1 - 0.00044 20.3 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK45299.1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KKK45299.1 - 0.0017 18.2 0.0 0.81 9.4 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KKK45299.1 - 0.0046 16.9 0.1 0.0069 16.3 0.1 1.3 1 0 0 1 1 1 1 NTPase Gtr1_RagA PF04670.12 KKK45299.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KKK45299.1 - 0.0076 16.5 0.1 0.11 12.8 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KKK45299.1 - 0.008 15.9 0.3 0.0098 15.6 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK45299.1 - 0.022 15.1 0.1 0.022 15.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KKK45299.1 - 0.03 13.5 0.2 0.056 12.6 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain Fer4_NifH PF00142.18 KKK45299.1 - 0.041 13.3 0.2 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PduV-EutP PF10662.9 KKK45299.1 - 0.062 13.0 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 KKK45299.1 - 0.079 13.0 0.2 0.21 11.6 0.2 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 KKK45299.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 2 0 0 2 2 2 0 ABC transporter TPP_enzyme_C PF02775.21 KKK45300.1 - 9.6e-23 80.7 0.0 1.9e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.27 KKK45300.1 - 1.5e-09 37.2 3.7 1.5e-09 37.2 3.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain POR_N PF01855.19 KKK45300.1 - 1.2e-08 35.0 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fer4_7 PF12838.7 KKK45300.1 - 1.4e-06 28.8 6.8 4.7e-06 27.1 6.8 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45300.1 - 2.3e-06 27.4 3.8 2.3e-06 27.4 3.8 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 KKK45300.1 - 1.7e-05 24.9 10.9 1.7e-05 24.9 10.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45300.1 - 4e-05 23.4 2.1 4e-05 23.4 2.1 3.0 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 KKK45300.1 - 6e-05 23.1 22.9 0.00034 20.7 2.9 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45300.1 - 8.5e-05 22.6 8.7 0.00025 21.1 8.7 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45300.1 - 0.00054 20.8 6.2 0.00065 20.6 1.2 2.8 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK45300.1 - 0.0028 18.1 3.1 0.0028 18.1 3.1 2.8 3 0 0 3 3 1 1 4Fe-4S binding domain Fer4_13 PF13370.6 KKK45300.1 - 0.0045 17.5 2.8 0.0045 17.5 2.8 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KKK45300.1 - 0.016 15.9 1.4 0.051 14.3 1.4 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain DXP_synthase_N PF13292.6 KKK45300.1 - 0.039 13.2 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 KKK45300.1 - 0.092 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain ATP-synt_F PF01990.17 KKK45300.1 - 0.098 13.0 0.0 27 5.2 0.0 2.7 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit Fer4_17 PF13534.6 KKK45300.1 - 0.17 12.5 12.0 3.2 8.4 11.7 2.7 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45300.1 - 0.22 12.0 11.1 0.21 12.1 2.6 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain POR PF01558.18 KKK45302.1 - 1.7e-12 47.7 0.0 2.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase HTH_47 PF16221.5 KKK45304.1 - 8.2e-05 22.1 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 winged helix-turn-helix TrmB PF01978.19 KKK45304.1 - 0.0063 16.4 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB FeoC PF09012.10 KKK45304.1 - 0.075 13.1 0.2 0.15 12.2 0.2 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator EF1_GNE PF00736.19 KKK45305.1 - 3.7e-11 43.1 0.0 4e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain MutL_C PF08676.11 KKK45306.1 - 3.4e-35 121.0 0.0 7.4e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KKK45306.1 - 1.8e-14 53.4 0.2 3.5e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HAND PF09110.11 KKK45306.1 - 0.024 15.4 2.6 0.052 14.3 2.6 1.5 1 0 0 1 1 1 0 HAND ABC_tran PF00005.27 KKK45308.1 - 3.6e-08 34.0 0.8 0.00032 21.2 0.0 2.5 3 0 0 3 3 3 2 ABC transporter RsgA_GTPase PF03193.16 KKK45308.1 - 0.0019 18.1 0.3 0.0045 16.9 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KKK45308.1 - 0.0025 17.3 0.4 0.021 14.2 0.2 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain IBR PF01485.21 KKK45308.1 - 0.0038 17.4 4.8 0.039 14.2 4.4 2.1 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain AAA_29 PF13555.6 KKK45308.1 - 0.0038 16.9 0.1 0.0081 15.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain zf-ribbon_3 PF13248.6 KKK45308.1 - 0.008 15.6 5.2 0.14 11.6 0.1 3.3 3 0 0 3 3 3 1 zinc-ribbon domain Pyridox_oxase_2 PF12766.7 KKK45308.1 - 0.013 16.1 0.0 0.027 15.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase AAA_23 PF13476.6 KKK45308.1 - 0.016 15.7 2.1 0.027 15.0 1.3 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKK45308.1 - 0.025 14.8 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DZR PF12773.7 KKK45308.1 - 0.027 14.5 4.4 2.5 8.2 3.6 2.4 2 1 0 2 2 2 0 Double zinc ribbon AAA_16 PF13191.6 KKK45308.1 - 0.033 14.6 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain HypA PF01155.19 KKK45308.1 - 0.034 14.2 0.5 0.7 9.9 0.6 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-tcix PF14952.6 KKK45308.1 - 0.046 13.4 0.3 0.046 13.4 0.3 3.1 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding cobW PF02492.19 KKK45308.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RecR PF02132.15 KKK45308.1 - 2.1 8.0 7.5 7 6.3 0.1 3.2 2 1 1 3 3 3 0 RecR protein YhfH PF14149.6 KKK45308.1 - 6.1 6.9 9.0 13 5.8 0.9 2.9 2 1 1 3 3 2 0 YhfH-like protein Inhibitor_I42 PF09394.10 KKK45309.1 - 0.062 13.7 0.4 0.18 12.2 0.1 1.9 1 1 0 1 1 1 0 Chagasin family peptidase inhibitor I42 Antig_Caf1 PF09255.10 KKK45309.1 - 0.17 12.0 4.1 0.63 10.2 0.6 2.3 2 0 0 2 2 2 0 Caf1 Capsule antigen Abhydrolase_1 PF00561.20 KKK45310.1 - 2.8e-24 86.2 0.0 2.3e-23 83.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KKK45310.1 - 3.9e-13 49.2 0.2 1.1e-11 44.5 0.2 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KKK45310.1 - 2.9e-11 44.4 0.0 4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KKK45310.1 - 0.022 13.5 0.0 0.55 8.9 0.0 2.1 1 1 0 1 1 1 0 Ndr family Abhydrolase_5 PF12695.7 KKK45310.1 - 0.046 13.5 0.0 3.6 7.3 0.0 2.8 3 0 0 3 3 3 0 Alpha/beta hydrolase family DLH PF01738.18 KKK45310.1 - 0.056 13.0 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family ABC_tran PF00005.27 KKK45311.1 - 9.4e-23 81.2 2.2 9e-12 45.7 0.1 4.2 3 1 0 3 3 3 3 ABC transporter UvrA_DNA-bind PF17755.1 KKK45311.1 - 1.5e-16 60.7 0.0 3.3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 UvrA DNA-binding domain SMC_N PF02463.19 KKK45311.1 - 2.8e-13 49.8 2.4 0.00078 18.9 0.0 4.1 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KKK45311.1 - 5.8e-08 32.4 0.9 0.0018 17.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KKK45311.1 - 8.6e-06 25.8 3.7 0.096 12.5 0.0 4.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKK45311.1 - 1.1e-05 25.9 0.0 0.14 12.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KKK45311.1 - 3.4e-05 23.8 0.9 0.33 10.8 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase DnaJ_CXXCXGXG PF00684.19 KKK45311.1 - 3.7e-05 24.0 8.4 0.0053 17.1 0.2 3.4 3 0 0 3 3 3 1 DnaJ central domain AAA_15 PF13175.6 KKK45311.1 - 4.1e-05 23.5 9.0 1.7 8.2 0.3 4.8 5 0 0 5 5 5 3 AAA ATPase domain AAA_23 PF13476.6 KKK45311.1 - 0.0017 18.9 10.5 0.0073 16.8 0.5 3.4 3 1 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KKK45311.1 - 0.0029 17.4 0.1 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KKK45311.1 - 0.003 18.1 0.1 6.3 7.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KKK45311.1 - 0.011 15.3 0.1 3.8 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 KKK45311.1 - 0.011 15.1 0.3 0.86 8.9 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_33 PF13671.6 KKK45311.1 - 0.013 15.6 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK45311.1 - 0.023 14.7 0.0 3.3 7.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 KKK45311.1 - 0.038 13.7 2.1 11 5.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KKK45311.1 - 0.05 13.9 5.2 1.5 9.1 0.2 3.1 4 0 0 4 4 2 0 AAA domain ATPase_2 PF01637.18 KKK45311.1 - 0.053 13.4 0.2 12 5.7 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 KKK45311.1 - 0.056 13.5 0.8 1.5 9.0 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF2075 PF09848.9 KKK45311.1 - 0.067 12.4 0.2 0.54 9.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 KKK45311.1 - 0.081 12.5 0.6 9 5.8 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 KKK45311.1 - 0.097 12.6 0.1 3.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase NACHT PF05729.12 KKK45311.1 - 0.11 12.4 0.1 6.4 6.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain PRK PF00485.18 KKK45311.1 - 0.16 11.7 0.1 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KKK45311.1 - 0.2 10.9 0.0 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 KKK45311.1 - 2.2 8.3 5.9 27 4.7 0.2 3.6 4 0 0 4 4 4 0 Helicase HerA, central domain BtrH_N PF14399.6 KKK45312.1 - 1.5e-27 96.4 0.0 2.4e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Butirosin biosynthesis protein H, N-terminal DUF4872 PF16169.5 KKK45312.1 - 1.1e-23 83.9 0.0 3.5e-23 82.2 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4872) Peptidase_C39_2 PF13529.6 KKK45312.1 - 2.1e-05 25.1 0.0 9.2e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase_C39 like family PadR PF03551.14 KKK45313.1 - 2.6e-12 46.5 0.0 6.4e-12 45.3 0.0 1.7 1 1 1 2 2 2 1 Transcriptional regulator PadR-like family HTH_27 PF13463.6 KKK45313.1 - 0.0077 16.7 0.0 0.019 15.4 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain Maelstrom PF13017.6 KKK45313.1 - 0.011 15.5 0.7 0.025 14.2 0.4 1.8 1 1 0 1 1 1 0 piRNA pathway germ-plasm component TrmB PF01978.19 KKK45313.1 - 0.015 15.2 0.1 0.25 11.3 0.0 2.5 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rsbr_N PF08678.10 KKK45313.1 - 0.018 15.1 0.6 0.84 9.7 0.1 2.7 2 1 0 2 2 2 0 Rsbr N terminal HTH_34 PF13601.6 KKK45313.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain NosD PF05048.13 KKK45314.1 - 2.5e-49 167.7 121.2 3.3e-22 78.9 24.7 5.3 1 1 4 5 5 5 4 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK45314.1 - 1.3e-37 129.1 130.6 1.5e-12 47.7 33.9 5.0 2 1 3 5 5 5 4 Right handed beta helix region Rad50_zn_hook PF04423.14 KKK45317.1 - 0.018 14.9 0.3 0.025 14.4 0.3 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif YdjO PF14169.6 KKK45317.1 - 0.046 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Cold-inducible protein YdjO Prok-RING_4 PF14447.6 KKK45317.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 KKK45320.1 - 0.021 14.7 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 KKK45320.1 - 0.036 13.9 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CCG PF02754.16 KKK45324.1 - 1.5e-32 111.6 6.8 1.2e-17 63.9 0.1 3.4 2 1 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 KKK45324.1 - 9.8e-10 38.7 4.9 9.8e-10 38.7 4.9 3.3 4 0 0 4 4 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45324.1 - 1.8e-09 38.0 6.3 1.8e-09 38.0 6.3 3.3 4 0 0 4 4 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK45324.1 - 6.8e-09 36.2 4.3 6.8e-09 36.2 4.3 4.0 4 0 0 4 4 4 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45324.1 - 4.7e-06 26.7 3.8 4.7e-06 26.7 3.8 3.7 4 1 0 4 4 4 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45324.1 - 4.8e-06 26.2 20.8 0.00042 20.0 3.8 3.9 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45324.1 - 1.8e-05 25.6 5.2 1.8e-05 25.6 5.2 2.9 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK45324.1 - 2.9e-05 24.1 23.2 0.00013 22.0 11.5 4.1 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45324.1 - 0.00015 21.6 10.1 0.0031 17.5 1.0 3.9 5 0 0 5 5 4 2 4Fe-4S binding domain Desulfoferrod_N PF06397.12 KKK45324.1 - 0.012 15.2 0.5 0.012 15.2 0.5 3.1 4 0 0 4 4 2 0 Desulfoferrodoxin, N-terminal domain Fer4_4 PF12800.7 KKK45324.1 - 0.061 13.9 2.3 0.061 13.9 2.3 4.0 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK45324.1 - 0.091 13.0 11.1 0.18 12.0 7.5 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45324.1 - 0.12 12.5 15.4 0.2 11.8 0.6 3.9 5 0 0 5 5 4 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK45324.1 - 0.54 10.8 5.8 18 5.9 0.2 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_6 PF12837.7 KKK45324.1 - 1.1 9.5 22.8 0.13 12.4 5.4 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 KKK45324.1 - 4.6 8.1 7.0 7.7 7.3 0.3 3.3 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF35_N PF12172.8 KKK45325.1 - 3.4e-07 30.0 0.0 4.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) NMD3 PF04981.13 KKK45325.1 - 0.12 11.8 0.2 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 NMD3 family LRR_8 PF13855.6 KKK45326.1 - 1.7e-41 139.8 80.5 8.2e-10 38.3 7.2 8.1 3 2 6 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 KKK45326.1 - 4.8e-26 90.4 98.9 1e-06 29.0 4.0 10.3 6 3 5 11 11 11 10 Leucine Rich repeats (2 copies) HEAT_2 PF13646.6 KKK45326.1 - 5.5e-07 29.9 0.0 3.1e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 HEAT repeats LRR_1 PF00560.33 KKK45326.1 - 0.00019 21.6 80.8 2.9 8.8 1.3 15.4 14 2 0 14 14 14 6 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 KKK45326.1 - 0.028 14.5 3.6 53 4.0 0.0 5.8 6 1 2 8 8 8 0 RsmF rRNA methyltransferase first C-terminal domain OST-HTH PF12872.7 KKK45326.1 - 0.05 13.4 0.1 10 6.0 0.0 3.3 2 0 0 2 2 2 0 OST-HTH/LOTUS domain HEAT PF02985.22 KKK45326.1 - 0.13 12.6 0.0 0.48 10.8 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat LRR_6 PF13516.6 KKK45326.1 - 9.5 6.6 62.6 5.5 7.3 0.5 12.8 13 0 0 13 13 13 0 Leucine Rich repeat Actin PF00022.19 KKK45327.1 - 1.9e-20 72.9 0.1 3.5e-18 65.4 0.1 2.0 1 1 0 1 1 1 1 Actin HTH_45 PF14947.6 KKK45328.1 - 6.7e-06 26.0 0.6 9.3e-06 25.6 0.6 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix S10_plectin PF03501.15 KKK45328.1 - 0.065 13.3 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain MarR PF01047.22 KKK45329.1 - 9.3e-11 41.5 0.1 1.1e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 KKK45329.1 - 8.9e-10 38.3 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KKK45329.1 - 4.4e-08 32.5 0.2 7.4e-08 31.8 0.2 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 KKK45329.1 - 2.7e-06 27.8 0.0 3.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 KKK45329.1 - 0.0011 18.7 0.1 0.0018 18.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family RepL PF05732.11 KKK45329.1 - 0.0027 17.1 0.0 0.0033 16.9 0.0 1.1 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_micro PF17007.5 KKK45329.1 - 0.0083 15.0 0.5 0.0094 14.8 0.5 1.1 1 0 0 1 1 1 1 HTH-like HTH_Mga PF08280.11 KKK45329.1 - 0.016 15.2 0.3 0.024 14.7 0.3 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain TrmB PF01978.19 KKK45329.1 - 0.017 15.0 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 KKK45329.1 - 0.019 14.9 0.1 0.027 14.4 0.1 1.2 1 0 0 1 1 1 0 HTH domain HxlR PF01638.17 KKK45329.1 - 0.023 14.6 0.2 0.03 14.2 0.2 1.1 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_IclR PF09339.10 KKK45329.1 - 0.05 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain RNA_pol_Rpc34 PF05158.12 KKK45329.1 - 0.079 12.3 1.0 0.079 12.3 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_28 PF13518.6 KKK45329.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Inos-1-P_synth PF01658.17 KKK45329.1 - 0.14 12.4 0.2 0.18 12.1 0.2 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase ThiF PF00899.21 KKK45330.1 - 1.9e-61 207.6 0.0 2.3e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KKK45330.1 - 0.0066 16.7 0.1 0.019 15.2 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KKK45330.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KKK45330.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KKK45330.1 - 0.11 11.8 0.1 0.42 10.0 0.0 1.9 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CheW PF01584.19 KKK45330.1 - 0.11 12.1 0.1 0.7 9.5 0.1 2.0 1 1 0 1 1 1 0 CheW-like domain TusA PF01206.17 KKK45331.1 - 9.4e-20 70.2 0.1 1.1e-19 70.0 0.1 1.1 1 0 0 1 1 1 1 Sulfurtransferase TusA NFACT-R_2 PF18297.1 KKK45332.1 - 8.3e-22 77.4 0.1 1.3e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain ThiI PF02568.14 KKK45332.1 - 7.1e-07 29.0 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NFACT-R_1 PF05670.13 KKK45332.1 - 0.00037 21.1 0.1 0.0012 19.5 0.0 1.8 2 0 0 2 2 2 1 NFACT protein RNA binding domain tRNA_Me_trans PF03054.16 KKK45332.1 - 0.0018 17.1 0.0 0.0042 15.9 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase PAS_9 PF13426.7 KKK45333.1 - 2.2e-28 98.6 1.4 3.6e-09 36.8 0.0 4.5 4 1 0 4 4 4 4 PAS domain PAS PF00989.25 KKK45333.1 - 1.3e-27 96.0 0.0 4.9e-10 39.4 0.0 4.4 4 0 0 4 4 4 4 PAS fold PAS_3 PF08447.12 KKK45333.1 - 2.1e-27 95.2 0.1 6.6e-13 48.8 0.0 4.5 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 KKK45333.1 - 2.8e-25 87.8 0.0 4.8e-06 26.5 0.0 4.4 4 0 0 4 4 4 4 PAS domain PAS_4 PF08448.10 KKK45333.1 - 4.5e-17 62.3 0.0 1.5e-09 38.1 0.0 4.0 4 0 0 4 4 4 2 PAS fold PAS_11 PF14598.6 KKK45333.1 - 0.0086 16.2 0.1 0.036 14.2 0.1 2.1 1 0 0 1 1 1 1 PAS domain DMPK_coil PF08826.10 KKK45333.1 - 0.21 11.7 14.6 5.2 7.3 0.4 4.5 4 0 0 4 4 4 0 DMPK coiled coil domain like RolB_RolC PF02027.17 KKK45333.1 - 0.23 11.1 1.8 13 5.4 0.1 3.2 3 0 0 3 3 3 0 RolB/RolC glucosidase family Holin_BhlA PF10960.8 KKK45333.1 - 1.5 8.8 16.3 0.21 11.6 0.5 3.7 4 0 0 4 4 4 0 BhlA holin family UQ_con PF00179.26 KKK45336.1 - 6.5e-25 87.4 0.0 7.7e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KKK45336.1 - 0.033 14.5 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain dsDNA_bind PF01984.20 KKK45337.1 - 0.0043 17.3 2.1 0.026 14.8 0.1 2.1 1 1 1 2 2 2 2 Double-stranded DNA-binding domain DUF5617 PF18493.1 KKK45338.1 - 0.0074 16.4 0.2 0.032 14.3 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF5617) Hist_deacetyl PF00850.19 KKK45339.1 - 8.2e-75 252.1 0.0 9.8e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain AsiA PF09010.10 KKK45339.1 - 0.075 13.2 0.0 0.5 10.5 0.0 2.4 3 0 0 3 3 3 0 Anti-Sigma Factor A DUF3461 PF11944.8 KKK45340.1 - 0.044 13.9 0.6 0.071 13.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) TrmB PF01978.19 KKK45341.1 - 4e-18 65.0 0.0 6.5e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Regulator_TrmB PF11495.8 KKK45341.1 - 1.1e-06 28.1 0.0 1.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB PLDc_2 PF13091.6 KKK45341.1 - 0.0044 16.9 0.0 0.0092 15.9 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain HTH_IclR PF09339.10 KKK45341.1 - 0.042 13.7 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain DprA_WH PF17782.1 KKK45341.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 DprA winged helix domain DHHC PF01529.20 KKK45342.1 - 0.48 10.5 7.3 0.6 10.2 7.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Spo7 PF03907.13 KKK45343.1 - 0.16 11.5 0.7 0.16 11.4 0.7 1.0 1 0 0 1 1 1 0 Spo7-like protein DUF4190 PF13828.6 KKK45344.1 - 9.6 6.1 16.3 42 4.0 15.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4190) Cg6151-P PF10233.9 KKK45346.1 - 0.076 13.3 0.9 0.11 12.8 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P HTH_AsnC-type PF13404.6 KKK45347.1 - 2.3e-14 52.9 0.9 3e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK45347.1 - 2.4e-14 52.6 0.5 2.4e-14 52.6 0.5 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 KKK45347.1 - 7.8e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_5 PF01022.20 KKK45347.1 - 1.3e-05 25.0 0.2 2.8e-05 23.9 0.0 1.6 2 0 0 2 2 1 1 Bacterial regulatory protein, arsR family HTH_DeoR PF08220.12 KKK45347.1 - 7.9e-05 22.3 0.3 0.00016 21.3 0.3 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KKK45347.1 - 0.00018 21.3 3.0 0.00024 21.0 0.3 2.1 2 0 0 2 2 2 1 HTH domain HTH_20 PF12840.7 KKK45347.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 KKK45347.1 - 0.00066 19.6 0.3 0.0013 18.6 0.0 1.6 2 0 0 2 2 1 1 MarR family HTH_38 PF13936.6 KKK45347.1 - 0.00075 19.2 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KKK45347.1 - 0.00097 18.5 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 KKK45347.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 KKK45347.1 - 0.0022 17.5 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.10 KKK45347.1 - 0.0031 17.3 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF977 PF06163.11 KKK45347.1 - 0.0034 17.3 0.2 0.026 14.4 0.1 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF977) Sigma70_r4_2 PF08281.12 KKK45347.1 - 0.0045 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 KKK45347.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_Mga PF08280.11 KKK45347.1 - 0.012 15.6 2.1 0.012 15.6 0.1 2.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain MarR_2 PF12802.7 KKK45347.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.6 KKK45347.1 - 0.037 14.2 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain CtsR_C PF17727.1 KKK45347.1 - 0.047 13.8 1.0 3.4 7.9 0.0 3.0 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain HTH_12 PF08461.10 KKK45347.1 - 0.054 13.4 0.5 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF4878 PF12870.7 KKK45347.1 - 0.069 13.5 0.4 0.13 12.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) TFIIE_alpha PF02002.17 KKK45347.1 - 0.071 13.0 1.5 0.15 11.9 1.3 1.7 1 1 0 1 1 1 0 TFIIE alpha subunit RuvB_C PF05491.13 KKK45347.1 - 0.09 12.7 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain HTH_28 PF13518.6 KKK45347.1 - 0.097 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Crp PF00325.20 KKK45347.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Med21 PF11221.8 KKK45347.1 - 0.16 12.2 0.3 0.21 11.8 0.3 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex HMGL-like PF00682.19 KKK45348.1 - 9e-65 218.8 0.0 1.5e-64 218.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like YgaB PF14182.6 KKK45348.1 - 0.035 14.5 1.7 0.074 13.5 0.5 2.2 2 0 0 2 2 2 0 YgaB-like protein Phage_int_SAM_5 PF13102.6 KKK45348.1 - 0.32 11.3 2.1 23 5.4 0.0 3.1 2 1 1 3 3 3 0 Phage integrase SAM-like domain Nup54 PF13874.6 KKK45349.1 - 0.092 12.9 1.2 0.18 11.9 1.2 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ThuA PF06283.11 KKK45349.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation NTP_transferase PF00483.23 KKK45350.1 - 2e-22 80.0 0.0 2.5e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KKK45350.1 - 7.2e-05 22.4 6.4 0.024 14.4 0.2 3.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKK45350.1 - 0.0023 18.3 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 KKK45350.1 - 0.0025 17.6 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 KKK45350.1 - 0.046 12.7 0.2 0.096 11.6 0.2 1.5 1 0 0 1 1 1 0 L-fucokinase ATP_bind_1 PF03029.17 KKK45351.1 - 4.7e-51 173.9 0.0 5.3e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KKK45351.1 - 0.00071 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KKK45351.1 - 0.00086 19.0 0.2 1.3 8.6 0.0 2.8 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KKK45351.1 - 0.002 18.7 0.1 0.0088 16.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KKK45351.1 - 0.0026 17.7 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase CLP1_P PF16575.5 KKK45351.1 - 0.0028 17.5 0.0 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KKK45351.1 - 0.043 14.2 0.0 0.085 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 KKK45351.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 KKK45351.1 - 0.099 12.9 0.2 0.18 12.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK45351.1 - 0.13 12.7 0.2 0.54 10.7 0.0 2.2 3 0 0 3 3 3 0 RNA helicase AAA_29 PF13555.6 KKK45351.1 - 0.34 10.7 1.2 0.62 9.8 0.4 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4471 PF14740.6 KKK45353.1 - 0.028 13.7 0.2 0.03 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) N6_N4_Mtase PF01555.18 KKK45354.1 - 3.4e-53 180.7 0.6 4.1e-53 180.5 0.6 1.1 1 0 0 1 1 1 1 DNA methylase Methyltransf_31 PF13847.6 KKK45354.1 - 3.8e-06 26.8 0.0 0.0011 18.8 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KKK45354.1 - 5.1e-05 23.9 0.0 0.0046 17.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK45354.1 - 0.00022 21.8 0.0 1.5 9.5 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain MethyltransfD12 PF02086.15 KKK45354.1 - 0.0047 16.6 0.2 1.5 8.5 0.1 2.4 2 0 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase Met_10 PF02475.16 KKK45354.1 - 0.0069 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 KKK45354.1 - 0.0094 15.5 0.0 0.43 10.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 KKK45354.1 - 0.0098 15.5 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KKK45354.1 - 0.042 13.5 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 KKK45354.1 - 0.055 14.2 0.0 5.8 7.7 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DUF835 PF05763.12 KKK45355.1 - 0.011 15.4 0.2 0.015 15.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF835) KH_6 PF15985.5 KKK45355.1 - 0.069 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 KH domain CMD PF02627.20 KKK45356.1 - 6.1e-09 35.8 0.0 9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Sigma70_r4 PF04545.16 KKK45356.1 - 0.0062 16.0 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Lambda_CIII PF02061.16 KKK45356.1 - 0.088 12.9 0.1 2.1 8.5 0.0 2.8 3 0 0 3 3 3 0 Lambda Phage CIII DZR PF12773.7 KKK45357.1 - 2.4e-12 46.7 20.6 5.2e-08 32.8 12.0 2.5 2 1 0 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK45357.1 - 5.7e-09 35.1 20.0 0.00013 21.2 3.8 4.1 4 0 0 4 4 4 3 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK45357.1 - 9.6e-09 34.7 27.9 0.0056 16.4 4.7 3.9 3 1 0 3 3 3 3 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK45357.1 - 0.0005 20.8 17.8 0.074 13.8 5.5 2.8 1 1 1 2 2 2 2 zinc-ribbon family TackOD1 PF18551.1 KKK45357.1 - 0.00099 18.8 13.4 0.0051 16.5 13.4 2.0 1 1 0 1 1 1 1 Thaumarchaeal output domain 1 DUF2207 PF09972.9 KKK45357.1 - 0.0049 15.7 0.3 0.0053 15.6 0.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) zf-RRN7 PF11781.8 KKK45357.1 - 0.014 15.1 13.4 35 4.2 0.3 5.2 4 1 1 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nudix_N_2 PF14803.6 KKK45357.1 - 0.036 14.0 18.6 3.6 7.6 0.2 5.6 5 1 1 6 6 6 0 Nudix N-terminal zf_UBZ PF18439.1 KKK45357.1 - 0.038 13.6 22.4 2.1 8.0 0.3 6.1 4 1 2 6 6 6 0 Ubiquitin-Binding Zinc Finger zinc-ribbons_6 PF07191.12 KKK45357.1 - 0.042 13.8 17.5 4 7.5 9.8 3.0 1 1 1 2 2 2 0 zinc-ribbons PHF5 PF03660.14 KKK45357.1 - 0.049 13.8 10.3 0.14 12.4 4.2 2.1 2 0 0 2 2 2 0 PHF5-like protein NinF PF05810.12 KKK45357.1 - 0.069 13.0 0.5 0.069 13.0 0.5 3.1 2 1 1 3 3 3 0 NinF protein UPF0547 PF10571.9 KKK45357.1 - 0.17 12.0 17.9 7.7 6.7 0.2 4.6 3 1 1 4 4 4 0 Uncharacterised protein family UPF0547 FYVE_2 PF02318.16 KKK45357.1 - 0.32 11.2 9.7 0.39 10.9 4.0 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger zinc-ribbon_6 PF10005.9 KKK45357.1 - 0.48 11.2 12.0 3.7 8.3 0.3 3.2 2 1 1 3 3 3 0 zinc-ribbon domain C1_1 PF00130.22 KKK45357.1 - 0.51 10.3 16.3 5.7 6.9 0.2 3.5 2 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) VirB3 PF05101.13 KKK45357.1 - 0.55 10.5 4.8 0.76 10.0 4.8 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein PolC_DP2 PF03833.13 KKK45357.1 - 1.1 7.1 9.7 0.03 12.2 2.8 1.7 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 DUF2321 PF10083.9 KKK45357.1 - 1.2 8.7 16.8 41 3.8 2.1 3.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C3HC4_3 PF13920.6 KKK45357.1 - 3.3 7.6 22.6 0.63 10.0 0.2 4.2 2 2 2 4 4 4 0 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.6 KKK45357.1 - 4.5 7.3 29.4 3 7.9 0.1 5.7 3 1 3 6 6 6 0 YhfH-like protein TMEM208_SND2 PF05620.11 KKK45357.1 - 5.6 6.7 6.9 10 5.9 7.0 1.4 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 zf-C2HC5 PF06221.13 KKK45357.1 - 5.9 7.0 19.1 1.7 8.7 0.9 3.8 2 2 2 4 4 4 0 Putative zinc finger motif, C2HC5-type zf-B_box PF00643.24 KKK45357.1 - 6 7.1 21.8 4.3 7.6 1.5 3.9 2 2 1 3 3 3 0 B-box zinc finger Prok-RING_1 PF14446.6 KKK45357.1 - 7.3 6.6 20.4 0.24 11.3 0.8 3.4 2 1 2 4 4 4 0 Prokaryotic RING finger family 1 DUF1700 PF08006.11 KKK45357.1 - 8.4 5.9 7.7 11 5.5 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Prok-RING_1 PF14446.6 KKK45358.1 - 3.3e-05 23.7 1.7 4.3e-05 23.3 1.7 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 KKK45358.1 - 0.00027 20.7 1.0 0.00029 20.6 1.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 KKK45358.1 - 0.00078 19.4 0.5 0.00089 19.2 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C2HC5 PF06221.13 KKK45358.1 - 0.0082 16.1 0.9 0.0098 15.9 0.9 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-RING_4 PF14570.6 KKK45358.1 - 0.0083 15.9 0.8 0.0084 15.9 0.8 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain HypA PF01155.19 KKK45358.1 - 0.013 15.5 0.7 0.013 15.5 0.7 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 KKK45358.1 - 0.033 13.7 2.0 4.7 6.8 0.1 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 KKK45358.1 - 0.043 13.5 3.0 0.099 12.4 3.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK45358.1 - 0.06 12.8 4.7 0.62 9.6 4.7 2.1 1 1 0 1 1 1 0 zinc-ribbon domain DUF1258 PF06869.12 KKK45358.1 - 0.083 12.4 0.8 0.081 12.4 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Cas_CXXC_CXXC PF09706.10 KKK45358.1 - 0.25 11.6 4.2 4.3 7.6 0.6 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Ribosomal_S30 PF04758.14 KKK45359.1 - 1.2e-12 47.8 1.3 1.2e-12 47.8 1.3 1.6 1 1 1 2 2 2 1 Ribosomal protein S30 TPR_2 PF07719.17 KKK45360.1 - 2.4e-09 36.6 0.6 0.012 15.6 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK45360.1 - 5.8e-06 26.5 0.0 0.013 15.8 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK45360.1 - 0.00023 20.7 0.0 0.086 12.2 0.0 2.3 1 1 2 3 3 3 3 MalT-like TPR region RPN7 PF10602.9 KKK45360.1 - 0.00066 19.4 3.8 0.0024 17.6 0.9 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN7 SNAP PF14938.6 KKK45360.1 - 0.0042 16.6 0.3 0.0076 15.7 0.3 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 KKK45360.1 - 0.0059 16.4 5.3 0.52 10.2 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF410 PF04190.13 KKK45360.1 - 0.014 15.2 2.3 0.022 14.6 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF410) TPR_10 PF13374.6 KKK45360.1 - 0.016 15.1 0.0 25 4.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KKK45360.1 - 0.04 14.6 0.0 10 7.0 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK45360.1 - 0.12 12.9 0.2 63 4.2 0.0 4.1 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK45360.1 - 3.3 8.2 7.4 84 3.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zinc_ribbon_2 PF13240.6 KKK45361.1 - 2.9e-05 23.6 3.0 6e-05 22.6 3.0 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK45361.1 - 0.00024 20.4 1.7 0.00038 19.7 1.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK45361.1 - 0.0021 18.1 3.1 0.0033 17.4 3.1 1.3 1 0 0 1 1 1 1 Double zinc ribbon RNase_E_G PF10150.9 KKK45361.1 - 0.0087 15.5 1.0 0.0087 15.5 1.0 1.8 1 1 1 2 2 2 1 Ribonuclease E/G family FUR PF01475.19 KKK45361.1 - 0.017 15.3 0.8 1.7 8.8 0.1 2.6 2 1 0 2 2 2 0 Ferric uptake regulator family zf-RanBP PF00641.18 KKK45361.1 - 0.89 8.9 4.2 1.6 8.1 4.2 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others MoCF_biosynth PF00994.24 KKK45363.1 - 4.7e-27 94.4 0.0 5.4e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain B12-binding PF02310.19 KKK45363.1 - 0.043 13.9 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain LPD15 PF18828.1 KKK45363.1 - 0.067 13.1 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 Gtr1_RagA PF04670.12 KKK45368.1 - 2.2e-19 69.7 1.7 4.7e-19 68.7 1.7 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK45368.1 - 5e-16 58.6 0.2 1.3e-15 57.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KKK45368.1 - 1e-07 32.2 0.0 2.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKK45368.1 - 1e-06 28.3 5.6 3e-06 26.8 0.3 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KKK45368.1 - 5.5e-05 22.8 1.5 5.8e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 Ras family DUF4277 PF14104.6 KKK45368.1 - 0.056 13.8 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) MtrH PF02007.18 KKK45369.1 - 7.2e-56 189.5 0.0 9.1e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit Exosortase_EpsH PF09721.10 KKK45370.1 - 0.00094 18.8 4.1 0.0017 18.0 4.1 1.3 1 0 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) TctB PF07331.11 KKK45370.1 - 0.017 15.4 5.0 0.062 13.6 4.7 1.9 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Papilloma_E5 PF03025.14 KKK45371.1 - 0.07 13.3 6.7 0.12 12.5 6.7 1.4 1 1 0 1 1 1 0 Papillomavirus E5 DUF4896 PF16237.5 KKK45371.1 - 0.11 12.4 9.2 0.2 11.5 9.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4896) DUF2207 PF09972.9 KKK45371.1 - 0.3 9.8 2.1 0.32 9.7 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TBP PF00352.21 KKK45372.1 - 1.4e-35 121.1 0.5 2.8e-17 62.5 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF1340 PF07067.11 KKK45372.1 - 0.035 13.5 0.1 0.043 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) CHMI PF02962.15 KKK45372.1 - 0.12 12.8 0.0 24 5.3 0.0 2.2 2 0 0 2 2 2 0 5-carboxymethyl-2-hydroxymuconate isomerase CxxCxxCC PF03692.15 KKK45373.1 - 8.6e-09 36.0 0.5 4.7e-08 33.6 0.5 2.2 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF445 PF04286.12 KKK45378.1 - 0.029 14.2 1.3 0.08 12.7 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1722 PF08349.11 KKK45378.1 - 0.047 14.0 1.2 0.27 11.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) DUF1400 PF07176.11 KKK45378.1 - 0.057 13.7 1.1 0.12 12.6 0.9 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) MNE1 PF13762.6 KKK45378.1 - 0.095 12.7 6.0 0.25 11.3 1.4 2.4 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component DUF496 PF04363.12 KKK45378.1 - 0.14 12.2 0.1 0.8 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF496) GrpE PF01025.19 KKK45378.1 - 4.3 7.0 6.1 1.5 8.5 0.1 2.1 1 1 0 2 2 2 0 GrpE Daxx PF03344.15 KKK45379.1 - 0.11 12.6 1.1 0.22 11.6 0.1 1.9 2 1 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain MCPsignal PF00015.21 KKK45380.1 - 9.5e-34 116.7 9.5 9.5e-34 116.7 9.5 3.3 3 1 1 4 4 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 KKK45380.1 - 4.1e-08 33.5 1.6 7.5e-07 29.4 0.1 3.7 4 0 0 4 4 3 1 HAMP domain 4HB_MCP_1 PF12729.7 KKK45380.1 - 6.4e-08 32.3 0.2 6.4e-08 32.3 0.2 5.8 5 2 0 5 5 4 1 Four helix bundle sensory module for signal transduction Sec34 PF04136.15 KKK45380.1 - 0.0044 16.9 0.3 0.0044 16.9 0.3 3.9 3 1 1 4 4 4 1 Sec34-like family DUF2207 PF09972.9 KKK45380.1 - 0.01 14.6 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Med9 PF07544.13 KKK45380.1 - 0.1 12.7 3.2 0.56 10.3 0.3 3.4 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 H-kinase_dim PF02895.14 KKK45380.1 - 0.11 12.9 11.1 19 5.8 0.1 5.1 4 2 0 4 4 4 0 Signal transducing histidine kinase, homodimeric domain Fzo_mitofusin PF04799.13 KKK45380.1 - 0.11 12.0 8.4 0.12 11.9 0.2 3.3 2 1 1 3 3 3 0 fzo-like conserved region Serine_rich PF08824.10 KKK45380.1 - 0.12 12.3 8.7 4.2 7.4 1.6 3.4 3 0 0 3 3 3 0 Serine rich protein interaction domain Sec8_exocyst PF04048.14 KKK45380.1 - 0.14 12.0 13.6 1.5 8.7 4.4 3.2 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain T7SS_ESX_EspC PF10824.8 KKK45380.1 - 0.3 11.6 6.1 1.2 9.6 0.3 3.3 3 1 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm AI-2E_transport PF01594.16 KKK45380.1 - 0.31 10.2 6.8 0.15 11.2 3.5 2.2 3 0 0 3 3 3 0 AI-2E family transporter DUF4422 PF14393.6 KKK45380.1 - 0.4 10.5 5.1 16 5.3 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4422) DUF2203 PF09969.9 KKK45380.1 - 0.98 10.1 8.2 3.1 8.5 0.5 4.0 3 2 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 KKK45380.1 - 1.1 9.5 23.5 0.55 10.5 0.2 5.7 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 KKK45380.1 - 1.2 8.3 7.2 4.8 6.3 2.0 2.5 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 KKK45380.1 - 1.9 8.6 18.0 1.9 8.5 4.6 4.3 4 2 2 6 6 5 0 Protein of unknown function (DUF1664) Arfaptin PF06456.13 KKK45380.1 - 3.3 7.2 7.9 0.73 9.4 0.6 3.1 4 0 0 4 4 4 0 Arfaptin-like domain CDT1_C PF16679.5 KKK45380.1 - 3.4 8.2 10.6 13 6.3 0.0 3.9 5 1 0 5 5 2 0 DNA replication factor Cdt1 C-terminal domain HAUS-augmin3 PF14932.6 KKK45380.1 - 3.8 7.0 7.1 0.8 9.2 1.6 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Vps51 PF08700.11 KKK45380.1 - 5.7 7.1 13.6 13 5.9 0.1 5.0 4 1 1 5 5 5 0 Vps51/Vps67 Fez1 PF06818.15 KKK45380.1 - 5.8 7.3 13.3 4.6e+02 1.1 0.0 3.2 1 1 0 2 2 2 0 Fez1 MRPL52 PF18699.1 KKK45380.1 - 7.2 6.9 6.3 46 4.3 0.0 3.7 3 1 0 3 3 3 0 Mitoribosomal protein mL52 Herpes_IE2_3 PF03361.14 KKK45380.1 - 7.4 6.4 8.7 0.79 9.6 0.1 3.2 4 0 0 4 4 4 0 Herpes virus intermediate/early protein 2/3 SepSecS PF05889.13 KKK45383.1 - 2.3e-117 392.0 0.0 2.6e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 KKK45383.1 - 0.00036 19.8 0.0 0.00058 19.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3135 PF11333.8 KKK45383.1 - 0.0037 17.5 0.1 1.9 8.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3135) Cas_Csd1 PF09709.10 KKK45383.1 - 0.14 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) ABC_tran_CTD PF16326.5 KKK45385.1 - 0.00038 20.6 1.4 0.001 19.2 1.4 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain Apolipoprotein PF01442.18 KKK45385.1 - 0.00095 19.1 0.7 0.0016 18.4 0.7 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DASH_Dam1 PF08653.10 KKK45385.1 - 0.0046 16.7 7.8 0.026 14.3 1.1 3.0 3 1 1 4 4 3 2 DASH complex subunit Dam1 Bacillus_HBL PF05791.11 KKK45385.1 - 0.0083 16.0 4.8 0.0083 16.0 4.8 1.9 1 1 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Mce4_CUP1 PF11887.8 KKK45385.1 - 0.0088 15.5 2.9 0.075 12.5 0.3 2.0 1 1 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative NPV_P10 PF05531.12 KKK45385.1 - 0.012 16.1 11.9 1.5 9.3 11.9 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 KKK45385.1 - 0.012 13.6 6.4 0.014 13.4 6.4 1.0 1 0 0 1 1 1 0 Prominin HSBP1 PF06825.12 KKK45385.1 - 0.016 15.0 2.0 0.64 9.9 0.1 3.1 2 1 1 3 3 3 0 Heat shock factor binding protein 1 DUF5082 PF16888.5 KKK45385.1 - 0.018 15.3 2.8 0.018 15.3 2.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) MnmE_helical PF12631.7 KKK45385.1 - 0.019 15.1 5.6 0.28 11.3 5.6 2.1 1 1 0 1 1 1 0 MnmE helical domain DUF4407 PF14362.6 KKK45385.1 - 0.02 14.2 1.1 0.024 14.0 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KKK45385.1 - 0.021 14.9 5.3 0.028 14.4 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phasin PF05597.11 KKK45385.1 - 0.021 14.8 3.0 0.032 14.2 1.4 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DNA_pol_A PF00476.20 KKK45385.1 - 0.023 13.7 2.6 0.03 13.4 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase family A WASH_WAHD PF11945.8 KKK45385.1 - 0.025 14.1 0.7 0.043 13.3 0.7 1.4 1 0 0 1 1 1 0 WAHD domain of WASH complex Syntaxin-6_N PF09177.11 KKK45385.1 - 0.026 15.1 5.1 0.1 13.2 5.1 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 KKK45385.1 - 0.029 14.7 12.5 1.7 9.0 12.5 2.2 1 1 0 1 1 1 0 Syntaxin-like protein FliJ PF02050.16 KKK45385.1 - 0.03 14.5 0.4 0.03 14.5 0.4 1.9 2 1 0 2 2 2 0 Flagellar FliJ protein Matrilin_ccoil PF10393.9 KKK45385.1 - 0.03 14.2 4.6 3.7 7.5 0.2 3.8 2 1 2 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 KKK45385.1 - 0.032 14.3 13.0 0.19 11.7 12.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 KKK45385.1 - 0.037 13.4 9.7 0.089 12.1 9.7 1.7 1 1 0 1 1 1 0 SF-assemblin/beta giardin DUF2884 PF11101.8 KKK45385.1 - 0.038 13.5 0.6 0.038 13.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) RmuC PF02646.16 KKK45385.1 - 0.038 13.1 4.5 0.068 12.3 0.5 2.0 1 1 1 2 2 2 0 RmuC family ArsA_ATPase PF02374.15 KKK45385.1 - 0.043 13.0 3.0 0.33 10.1 0.3 2.0 1 1 1 2 2 2 0 Anion-transporting ATPase TPR_MLP1_2 PF07926.12 KKK45385.1 - 0.045 13.8 1.0 0.045 13.8 1.0 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 KKK45385.1 - 0.053 13.8 6.2 1.1 9.6 0.4 3.0 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 KKK45385.1 - 0.067 13.7 3.0 0.076 13.5 0.9 2.0 1 1 1 2 2 2 0 Spectrin repeat ACCA PF03255.14 KKK45385.1 - 0.077 12.9 0.6 0.077 12.9 0.6 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YkuI_C PF10388.9 KKK45385.1 - 0.083 12.7 1.0 0.12 12.2 0.5 1.5 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain ALMT PF11744.8 KKK45385.1 - 0.087 11.6 2.7 0.15 10.9 2.7 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter AKNA PF12443.8 KKK45385.1 - 0.098 13.3 2.5 5.1 7.8 0.2 2.9 1 1 2 3 3 3 0 AT-hook-containing transcription factor DASH_Dad4 PF08650.10 KKK45385.1 - 0.1 12.6 6.0 0.14 12.1 1.8 2.8 2 2 0 2 2 2 0 DASH complex subunit Dad4 ApoLp-III PF07464.11 KKK45385.1 - 0.12 12.5 8.7 3.5 7.7 8.4 2.3 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DASH_Hsk3 PF08227.11 KKK45385.1 - 0.12 12.7 7.9 3.6 8.0 1.5 3.2 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like LepB_N PF18640.1 KKK45385.1 - 0.13 11.9 2.1 0.17 11.5 0.9 1.7 1 1 1 2 2 2 0 LepB N-terminal domain DUF948 PF06103.11 KKK45385.1 - 0.15 12.4 5.0 1.8 8.9 5.0 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fibritin_C PF07921.12 KKK45385.1 - 0.15 12.2 1.8 0.21 11.7 1.8 1.4 1 1 0 1 1 1 0 Fibritin C-terminal region Gp-FAR-1 PF05823.12 KKK45385.1 - 0.15 12.4 3.0 0.19 12.0 1.3 1.9 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3510 PF12022.8 KKK45385.1 - 0.18 12.2 2.0 13 6.2 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) YtxH PF12732.7 KKK45385.1 - 0.21 12.1 3.4 2 9.0 0.2 2.4 2 1 0 2 2 2 0 YtxH-like protein Fib_alpha PF08702.10 KKK45385.1 - 0.21 11.8 9.1 0.45 10.7 4.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YvrJ PF12841.7 KKK45385.1 - 0.25 10.9 5.6 5.8 6.5 0.1 3.5 3 1 0 3 3 3 0 YvrJ protein family DUF2203 PF09969.9 KKK45385.1 - 0.3 11.8 2.9 0.19 12.5 0.4 1.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cor1 PF04803.12 KKK45385.1 - 0.31 11.2 4.3 0.25 11.6 0.4 2.3 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region AI-2E_transport PF01594.16 KKK45385.1 - 0.57 9.3 2.0 2 7.5 0.4 1.9 2 0 0 2 2 2 0 AI-2E family transporter Med4 PF10018.9 KKK45385.1 - 0.6 9.8 6.0 0.17 11.6 0.9 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Spc7 PF08317.11 KKK45385.1 - 0.62 8.9 8.5 1.4 7.7 8.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DASH_Dad3 PF08656.10 KKK45385.1 - 0.63 10.2 8.8 0.73 10.0 2.2 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 Fzo_mitofusin PF04799.13 KKK45385.1 - 0.68 9.5 3.7 0.58 9.7 0.6 1.9 1 1 0 2 2 2 0 fzo-like conserved region DUF2205 PF10224.9 KKK45385.1 - 0.8 9.7 9.3 1.2 9.1 1.0 3.3 2 2 1 3 3 3 0 Short coiled-coil protein Prefoldin PF02996.17 KKK45385.1 - 0.98 9.3 7.8 0.57 10.1 0.8 3.0 2 2 1 3 3 3 0 Prefoldin subunit Prefoldin_2 PF01920.20 KKK45385.1 - 1 9.3 9.5 0.11 12.5 1.1 2.8 2 2 1 3 3 3 0 Prefoldin subunit YabA PF06156.13 KKK45385.1 - 1.2 9.8 6.1 12 6.6 6.1 2.4 1 1 0 1 1 1 0 Initiation control protein YabA TMPIT PF07851.13 KKK45385.1 - 1.3 8.1 4.0 0.83 8.8 1.5 1.7 1 1 1 2 2 2 0 TMPIT-like protein SlyX PF04102.12 KKK45385.1 - 1.4 9.6 5.2 2.2 9.0 1.9 2.7 1 1 2 3 3 3 0 SlyX DUF4795 PF16043.5 KKK45385.1 - 2.2 7.8 8.9 8.8 5.9 8.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FlaC_arch PF05377.11 KKK45385.1 - 3 8.3 10.0 10 6.6 0.2 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Muted PF14942.6 KKK45386.1 - 0.0017 18.7 4.3 0.0017 18.7 4.3 1.7 1 1 1 2 2 2 1 Organelle biogenesis, Muted-like protein Peptidase_S39 PF02122.15 KKK45386.1 - 0.0045 16.5 0.1 0.0064 16.0 0.1 1.2 1 1 0 1 1 1 1 Peptidase S39 DUF948 PF06103.11 KKK45386.1 - 0.0088 16.3 3.9 0.33 11.3 3.8 2.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Integrin_beta PF00362.18 KKK45386.1 - 0.016 14.9 2.2 0.021 14.5 2.2 1.2 1 0 0 1 1 1 0 Integrin beta chain VWA domain SMC_ScpA PF02616.14 KKK45386.1 - 0.026 14.4 6.2 0.03 14.2 4.7 1.7 1 1 1 2 2 2 0 Segregation and condensation protein ScpA BAR_3 PF16746.5 KKK45386.1 - 0.038 13.7 9.0 0.053 13.2 9.0 1.3 1 0 0 1 1 1 0 BAR domain of APPL family ERK-JNK_inhib PF15002.6 KKK45386.1 - 0.073 12.8 9.5 0.12 12.0 8.3 1.7 1 1 1 2 2 2 0 ERK and JNK pathways, inhibitor FliJ PF02050.16 KKK45386.1 - 0.16 12.2 5.9 0.26 11.5 5.7 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein Caudo_TAP PF02413.17 KKK45386.1 - 0.17 12.0 2.6 0.24 11.5 2.6 1.4 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK YtxH PF12732.7 KKK45386.1 - 0.45 11.1 3.8 16 6.1 3.8 2.4 1 1 0 1 1 1 0 YtxH-like protein DASH_Dam1 PF08653.10 KKK45386.1 - 0.56 10.0 3.8 0.46 10.3 0.5 2.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF2935 PF11155.8 KKK45386.1 - 0.99 9.7 6.0 6.8 7.0 6.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF4795 PF16043.5 KKK45386.1 - 1 8.9 12.0 4.7 6.8 12.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 KKK45386.1 - 1.9 8.6 9.2 1.4 9.0 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 KKK45386.1 - 3.3 7.5 11.5 0.57 10.0 4.8 2.1 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.10 KKK45386.1 - 4.9 7.3 11.6 3.3 7.9 5.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AI-2E_transport PF01594.16 KKK45386.1 - 9.8 5.2 7.0 8.1 5.5 1.5 2.0 1 1 1 2 2 2 0 AI-2E family transporter SAM_adeno_trans PF01887.16 KKK45388.1 - 7.6e-68 228.5 0.1 8.6e-68 228.3 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase CTP_transf_like PF01467.26 KKK45389.1 - 3.3e-08 33.8 0.1 8e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Cytidylyltransferase-like NUDIX PF00293.28 KKK45389.1 - 3.8e-06 27.0 0.3 7.9e-06 25.9 0.3 1.6 1 1 0 1 1 1 1 NUDIX domain FAD_syn PF06574.12 KKK45389.1 - 0.047 13.6 0.3 2.5 8.0 0.1 2.4 1 1 1 2 2 2 0 FAD synthetase RTC PF01137.21 KKK45390.1 - 9.4e-59 198.3 0.0 1.1e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KKK45390.1 - 1e-09 38.8 0.0 1.6e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain zf-ribbon_3 PF13248.6 KKK45391.1 - 9.9e-05 21.6 1.4 0.00015 21.1 1.4 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK45391.1 - 0.0056 16.4 4.3 0.0089 15.7 4.3 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK45391.1 - 0.0066 16.5 1.0 0.011 15.7 1.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 KKK45391.1 - 0.042 13.9 0.5 0.077 13.1 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-RanBP PF00641.18 KKK45391.1 - 0.08 12.3 3.4 0.15 11.4 3.4 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Zn_Tnp_IS1595 PF12760.7 KKK45391.1 - 0.85 9.6 3.8 8.7 6.4 0.8 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain VPS28 PF03997.12 KKK45392.1 - 4.5e-08 33.0 4.3 6.1e-08 32.6 4.3 1.2 1 0 0 1 1 1 1 VPS28 protein RNA_binding PF01877.17 KKK45392.1 - 1.3 9.3 7.1 0.71 10.2 3.1 2.2 1 1 1 2 2 2 0 RNA binding Ribosomal_L34e PF01199.18 KKK45393.1 - 3.2e-17 62.6 5.3 3.5e-17 62.5 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e Cas_CXXC_CXXC PF09706.10 KKK45393.1 - 0.039 14.2 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-C3HC4_3 PF13920.6 KKK45393.1 - 0.096 12.6 2.2 1.1 9.1 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PLATZ PF04640.14 KKK45393.1 - 0.12 13.0 4.8 0.74 10.5 0.4 2.1 1 1 1 2 2 2 0 PLATZ transcription factor Cytidylate_kin2 PF13189.6 KKK45394.1 - 2.7e-22 79.8 0.5 3.6e-20 72.8 0.5 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 KKK45394.1 - 8.1e-19 68.5 0.2 1.1e-18 68.1 0.2 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KKK45394.1 - 9e-15 55.0 2.3 4.5e-07 29.8 0.3 2.1 1 1 1 2 2 2 2 Cytidylate kinase AAA_17 PF13207.6 KKK45394.1 - 3.5e-11 43.7 0.5 1e-10 42.2 0.4 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KKK45394.1 - 1.1e-05 25.6 1.7 2.5e-05 24.5 1.7 1.6 1 1 0 1 1 1 1 Shikimate kinase CoaE PF01121.20 KKK45394.1 - 0.00046 19.9 1.1 0.084 12.5 0.1 2.2 1 1 1 2 2 2 2 Dephospho-CoA kinase Thymidylate_kin PF02223.17 KKK45394.1 - 0.0038 16.9 7.5 0.59 9.8 0.2 2.7 1 1 2 3 3 3 2 Thymidylate kinase ADK PF00406.22 KKK45394.1 - 0.0074 16.4 0.2 0.012 15.7 0.2 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA PF00004.29 KKK45394.1 - 0.014 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KKK45394.1 - 0.023 15.2 0.1 0.029 14.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 KKK45394.1 - 0.042 13.7 0.1 0.077 12.9 0.1 1.6 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 KKK45394.1 - 0.091 12.9 0.1 0.19 11.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KKK45394.1 - 0.095 12.9 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KKK45394.1 - 0.096 12.7 0.2 0.096 12.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain Complex1_49kDa PF00346.19 KKK45394.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ribosomal_L14e PF01929.17 KKK45395.1 - 0.002 18.5 0.1 0.003 18.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 EMC3_TMCO1 PF01956.16 KKK45396.1 - 1.3e-21 77.0 5.9 2e-21 76.4 5.9 1.3 1 1 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Connexin PF00029.19 KKK45396.1 - 0.01 15.6 0.2 0.014 15.2 0.2 1.1 1 0 0 1 1 1 0 Connexin HemY_N PF07219.13 KKK45396.1 - 0.091 13.0 0.2 0.23 11.7 0.1 1.7 2 0 0 2 2 2 0 HemY protein N-terminus DUF4446 PF14584.6 KKK45396.1 - 0.17 11.9 2.0 0.27 11.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) LapA_dom PF06305.11 KKK45396.1 - 0.2 11.5 0.1 0.2 11.5 0.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1891 PF09004.10 KKK45396.1 - 2.5 7.7 5.8 12 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1891) Filamin PF00630.19 KKK45398.1 - 0.0015 19.3 0.1 0.048 14.5 0.0 2.9 2 0 0 2 2 2 1 Filamin/ABP280 repeat End_N_terminal PF12218.8 KKK45398.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Cadherin_5 PF17892.1 KKK45398.1 - 0.075 13.0 0.1 0.075 13.0 0.1 2.8 3 0 0 3 3 3 0 Cadherin-like domain PSI_PsaE PF02427.17 KKK45398.1 - 0.087 12.5 0.9 8.1 6.2 0.2 3.4 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IV / PsaE Invasin_D3 PF09134.10 KKK45398.1 - 0.47 10.8 6.6 0.33 11.3 0.2 3.5 4 0 0 4 4 4 0 Invasin, domain 3 Big_1 PF02369.16 KKK45398.1 - 0.87 9.6 4.5 2.1 8.4 1.3 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) rpo132 PF12415.8 KKK45399.1 - 0.17 11.2 1.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase Arf PF00025.21 KKK45400.1 - 1.8e-18 66.6 0.4 4.6e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KKK45400.1 - 2.1e-14 53.8 0.2 8.2e-14 51.9 0.0 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK45400.1 - 1.2e-13 51.0 0.2 3e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KKK45400.1 - 1.3e-06 28.4 0.0 7.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK45400.1 - 7.7e-06 25.4 1.0 0.00018 20.9 0.0 2.9 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK45400.1 - 2.8e-05 24.1 0.2 0.0055 16.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase BtpA PF03437.15 KKK45400.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 BtpA family ABC_tran PF00005.27 KKK45400.1 - 0.034 14.7 0.1 0.095 13.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter YqzH PF14164.6 KKK45400.1 - 0.057 13.5 0.3 0.4 10.8 0.1 2.4 3 0 0 3 3 2 0 YqzH-like protein AAA_24 PF13479.6 KKK45400.1 - 0.13 12.0 0.4 0.57 9.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain TPR_8 PF13181.6 KKK45400.1 - 0.13 12.5 0.7 0.77 10.1 0.5 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 KKK45400.1 - 0.16 12.3 2.1 0.58 10.4 0.6 2.6 2 2 0 2 2 2 0 AAA domain VASP_tetra PF08776.11 KKK45400.1 - 1.3 8.6 7.4 5.2 6.7 0.2 2.9 3 0 0 3 3 3 0 VASP tetramerisation domain Ca_bind_SSO6904 PF18249.1 KKK45400.1 - 1.8 8.9 5.9 1.7 9.0 3.9 2.1 2 0 0 2 2 2 0 Calcium binding protein SSO6904 Pyr_redox_2 PF07992.14 KKK45403.1 - 5.9e-12 45.4 0.6 4.1e-11 42.7 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK45403.1 - 9e-08 31.6 0.1 1.6e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KKK45403.1 - 2.4e-07 30.5 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK45403.1 - 8.3e-07 29.1 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KKK45403.1 - 2.4e-06 27.4 0.2 1.3e-05 24.9 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK45403.1 - 1.7e-05 23.7 0.4 0.0044 15.8 0.1 2.3 1 1 1 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KKK45403.1 - 5.6e-05 22.5 1.0 0.00016 21.0 1.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK45403.1 - 0.00014 21.1 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KKK45403.1 - 0.00034 20.0 0.0 0.00066 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KKK45403.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KKK45403.1 - 0.0027 18.2 1.3 0.037 14.6 1.3 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KKK45403.1 - 0.0049 16.0 3.2 0.0085 15.2 0.2 2.3 1 1 1 2 2 2 1 Glucose inhibited division protein A PCNA_N PF00705.18 KKK45403.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain DUF4342 PF14242.6 KKK45403.1 - 0.011 15.8 2.3 2.9 7.9 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4342) Trp_halogenase PF04820.14 KKK45403.1 - 0.11 11.3 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KKK45403.1 - 0.19 11.7 0.1 0.67 9.9 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KKK45407.1 - 1.9e-21 76.4 17.6 2.3e-21 76.1 17.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK45407.1 - 1.4e-12 47.3 16.5 1.7e-12 47.0 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 KKK45407.1 - 8e-07 27.8 3.3 8.6e-06 24.4 3.4 1.9 1 1 0 1 1 1 1 Transmembrane secretion effector TssN PF17555.2 KKK45407.1 - 0.14 11.5 18.8 0.18 11.2 18.8 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN Nop PF01798.18 KKK45408.1 - 0.051 13.0 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin DEAD PF00270.29 KKK45411.1 - 2.2e-21 76.4 0.2 2.9e-20 72.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KKK45411.1 - 3.7e-12 46.6 0.2 3.7e-12 46.6 0.2 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KKK45411.1 - 3.4e-09 36.9 0.1 8e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KKK45411.1 - 0.066 12.6 1.1 0.14 11.6 0.3 1.9 1 1 1 2 2 2 0 PhoH-like protein aGPT-Pplase2 PF18724.1 KKK45412.1 - 0.06 13.1 0.1 0.067 13.0 0.1 1.0 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 DnaJ_CXXCXGXG PF00684.19 KKK45413.1 - 9.1e-08 32.4 28.9 6.3e-06 26.5 15.4 2.3 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 KKK45413.1 - 0.4 10.7 14.2 4.1 7.4 0.3 3.5 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 KKK45413.1 - 0.41 10.7 7.5 4.7 7.3 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbons DUF3716 PF12511.8 KKK45413.1 - 1.2 9.3 8.2 1.8 8.7 5.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) Stc1 PF12898.7 KKK45413.1 - 1.5 9.5 10.5 1.6 9.3 2.4 2.6 1 1 1 2 2 2 0 Stc1 domain HypA PF01155.19 KKK45413.1 - 3.3 7.7 9.7 2.9 8.0 0.5 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C_GCAxxG_C_C PF09719.10 KKK45417.1 - 2.7e-24 85.7 0.1 2.9e-24 85.6 0.1 1.0 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) TPR_12 PF13424.6 KKK45418.1 - 7.8e-19 67.8 0.0 5.9e-07 29.7 0.0 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK45418.1 - 8.4e-12 44.4 3.1 0.02 14.7 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK45418.1 - 1.2e-08 34.3 0.4 0.013 15.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK45418.1 - 8.2e-08 31.9 1.0 0.097 12.9 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KKK45418.1 - 3.9e-07 29.7 0.3 0.4 10.9 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KKK45418.1 - 0.003 18.2 0.0 0.33 11.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 KKK45418.1 - 0.0031 17.7 0.8 17 6.0 0.0 3.6 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.6 KKK45418.1 - 0.0036 17.1 0.0 6.7 6.7 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 KKK45418.1 - 0.012 15.3 1.3 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_MalT PF17874.1 KKK45418.1 - 0.022 14.1 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 MalT-like TPR region SNAP PF14938.6 KKK45418.1 - 0.033 13.6 0.0 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP ANAPC5 PF12862.7 KKK45418.1 - 0.044 13.9 0.1 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 KKK45418.1 - 0.11 13.2 0.0 5 8.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 KKK45418.1 - 0.14 12.2 0.3 17 5.4 0.0 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) Ras PF00071.22 KKK45421.1 - 5.6e-25 87.8 0.0 6.3e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK45421.1 - 1.9e-11 44.2 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK45421.1 - 0.0044 16.5 0.0 0.0051 16.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MtrB PF05440.12 KKK45422.1 - 0.13 12.7 0.3 12 6.4 0.1 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B ClpB_D2-small PF10431.9 KKK45422.1 - 1.8 8.7 4.4 4.3 7.5 0.6 3.0 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein Polbeta PF18765.1 KKK45425.1 - 3.2e-19 68.8 1.3 3.2e-19 68.8 1.3 1.5 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK45425.1 - 2.2e-09 37.5 0.2 3e-09 37.0 0.2 1.4 1 1 0 1 1 1 1 Nucleotidyltransferase domain Adenyl_cycl_N PF12633.7 KKK45425.1 - 0.0083 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase NT domain HMGL-like PF00682.19 KKK45425.1 - 0.041 13.4 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 HMGL-like 3Beta_HSD PF01073.19 KKK45427.1 - 2.1e-16 59.8 0.0 2.4e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KKK45427.1 - 6.1e-10 39.0 0.0 7.1e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KKK45427.1 - 1.3e-08 35.0 0.0 1.5e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KKK45427.1 - 4.6e-08 32.5 0.0 5.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KKK45427.1 - 1.6e-06 27.8 0.0 1.9e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK45427.1 - 0.00016 20.9 0.0 0.0002 20.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK45427.1 - 0.00021 20.6 0.1 0.0022 17.2 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KKK45427.1 - 0.00052 19.5 0.0 0.00056 19.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KKK45427.1 - 0.0025 17.4 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family AlaDh_PNT_C PF01262.21 KKK45427.1 - 0.055 12.8 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.23 KKK45427.1 - 0.075 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GAF_2 PF13185.6 KKK45428.1 - 0.00029 21.1 0.0 0.00049 20.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KKK45428.1 - 0.0026 18.4 0.0 0.0045 17.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain AsnC_trans_reg PF01037.21 KKK45428.1 - 0.0027 17.7 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain GAF_3 PF13492.6 KKK45428.1 - 0.015 15.7 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 GAF domain His_Me_b4a2 PF18275.1 KKK45428.1 - 0.11 12.5 4.6 0.23 11.5 1.8 2.4 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain DUF443 PF04276.12 KKK45430.1 - 0.015 15.1 2.1 0.033 14.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF443) PMP1_2 PF08114.11 KKK45430.1 - 0.16 11.7 3.0 0.29 10.9 3.0 1.4 1 0 0 1 1 1 0 ATPase proteolipid family FeoB_associated PF12669.7 KKK45430.1 - 4.5 7.8 10.9 1.2 9.6 6.6 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Pyr_redox_2 PF07992.14 KKK45431.1 - 2.3e-08 33.6 0.1 3.2e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK45431.1 - 2.4e-08 34.1 0.0 3.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK45431.1 - 2.2e-07 30.6 0.2 3.1e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK45431.1 - 7.5e-07 28.6 1.5 1e-06 28.1 1.5 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KKK45431.1 - 4e-06 26.2 0.6 5.3e-06 25.8 0.6 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KKK45431.1 - 3.3e-05 23.3 0.1 3.3e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KKK45431.1 - 9e-05 22.2 0.4 0.00013 21.7 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK45431.1 - 0.00012 21.4 0.3 0.00017 21.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KKK45431.1 - 0.00012 22.5 0.1 0.00035 21.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KKK45431.1 - 0.00017 20.4 1.0 0.00022 20.0 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KKK45431.1 - 0.0011 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KKK45431.1 - 0.0012 18.1 0.2 0.0014 18.0 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KKK45431.1 - 0.0034 16.7 0.1 0.0036 16.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KKK45431.1 - 0.019 14.9 0.8 0.037 13.9 0.3 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KKK45431.1 - 0.021 13.9 0.4 0.028 13.5 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KKK45431.1 - 0.041 12.7 0.4 0.059 12.2 0.4 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KKK45431.1 - 0.055 13.5 0.1 0.097 12.7 0.1 1.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Nitro_FeMo-Co PF02579.17 KKK45431.1 - 0.1 12.9 0.3 0.19 12.1 0.3 1.5 1 1 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Fer4_7 PF12838.7 KKK45432.1 - 5.8e-16 58.8 26.6 9e-05 23.0 0.3 4.7 4 1 1 5 5 5 4 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45432.1 - 2.4e-15 55.6 40.8 1e-05 25.1 2.3 4.5 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_6 PF12837.7 KKK45432.1 - 5.3e-14 51.6 39.9 0.00025 21.0 2.4 4.5 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45432.1 - 6e-13 49.5 24.7 0.0026 18.6 2.1 4.7 4 0 0 4 4 4 4 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK45432.1 - 6.3e-12 45.5 36.8 9.3e-07 28.9 16.0 3.1 3 1 0 3 3 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45432.1 - 1.6e-10 40.9 40.6 7.5e-06 26.0 16.1 3.7 4 0 0 4 4 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45432.1 - 2.1e-09 36.9 39.7 8.5e-05 22.4 4.1 4.6 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_8 PF13183.6 KKK45432.1 - 3.4e-08 33.8 26.6 0.0065 16.9 11.5 4.4 3 1 2 5 5 5 4 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK45432.1 - 1.6e-06 28.6 30.4 0.0029 18.1 7.1 4.1 4 1 0 4 4 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK45432.1 - 5.1e-06 26.5 42.5 0.0027 17.8 12.5 4.2 3 2 2 5 5 5 4 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK45432.1 - 0.00013 22.2 41.5 0.0084 16.5 2.2 4.5 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_22 PF17179.4 KKK45432.1 - 0.00065 20.5 26.5 0.45 11.4 0.2 4.4 3 1 2 5 5 5 4 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK45432.1 - 0.011 16.0 25.3 0.8 9.9 0.3 4.0 3 1 1 4 4 4 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK45432.1 - 0.015 16.0 27.2 0.15 12.8 1.1 4.7 4 0 0 4 4 4 0 4Fe-4S single cluster domain DUF4033 PF13225.6 KKK45432.1 - 0.062 13.3 0.1 0.062 13.3 0.1 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF4033) Fer4_13 PF13370.6 KKK45432.1 - 2.1 9.0 32.4 0.68 10.5 1.2 4.6 4 0 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Adenosine_kin PF04008.14 KKK45433.1 - 0.023 14.5 0.0 0.026 14.3 0.0 1.0 1 0 0 1 1 1 0 Adenosine specific kinase FrhB_FdhB_C PF04432.13 KKK45434.1 - 2.5e-37 128.1 0.8 4.9e-37 127.1 0.0 1.8 2 0 0 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK45434.1 - 4.6e-21 74.7 0.4 1e-20 73.6 0.1 1.8 2 0 0 2 2 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Fer4 PF00037.27 KKK45434.1 - 4.7e-07 29.4 23.5 1.6e-05 24.5 5.3 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK45434.1 - 0.00041 20.3 13.1 0.00091 19.2 1.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_15 PF13459.6 KKK45434.1 - 0.00078 20.1 6.0 0.0024 18.6 0.1 2.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_8 PF13183.6 KKK45434.1 - 0.00098 19.5 4.4 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45434.1 - 0.001 19.6 13.9 0.001 19.6 13.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45434.1 - 0.0014 18.7 13.3 0.0014 18.7 13.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45434.1 - 0.0021 18.2 17.9 0.27 11.4 6.2 2.4 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK45434.1 - 0.0058 17.1 6.3 0.38 11.3 0.2 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK45434.1 - 0.0069 16.9 0.3 0.0069 16.9 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_10 PF13237.6 KKK45434.1 - 0.0069 16.5 18.5 0.022 14.9 1.9 2.7 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45434.1 - 0.01 15.9 2.3 0.01 15.9 2.3 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45434.1 - 0.027 15.4 15.0 0.086 13.8 3.5 3.0 2 1 1 3 3 2 0 4Fe-4S double cluster binding domain ApoA-II PF04711.13 KKK45434.1 - 0.043 14.0 1.1 4.7 7.4 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) B-block_TFIIIC PF04182.12 KKK45434.1 - 0.15 12.2 0.4 1.9 8.7 0.0 2.6 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC FrhB_FdhB_C PF04432.13 KKK45435.1 - 4.9e-36 123.9 0.0 9.9e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK45435.1 - 3.7e-15 55.8 0.0 8.5e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Fer4_9 PF13187.6 KKK45435.1 - 2.9e-06 27.3 7.9 2.9e-06 27.3 7.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45435.1 - 4.2e-06 26.8 8.0 4.2e-06 26.8 8.0 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45435.1 - 0.00015 22.3 8.3 0.00015 22.3 8.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK45435.1 - 0.00021 21.4 19.9 0.0033 17.5 10.7 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45435.1 - 0.00046 20.6 4.5 0.026 15.0 0.5 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45435.1 - 0.00064 20.6 7.7 0.077 13.9 0.6 3.4 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 KKK45435.1 - 0.0046 17.5 0.3 0.0046 17.5 0.3 2.9 3 0 0 3 3 3 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_2 PF12797.7 KKK45435.1 - 0.0069 16.4 1.9 0.0069 16.4 1.9 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK45435.1 - 0.0084 16.2 1.2 0.0084 16.2 1.2 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4 PF00037.27 KKK45435.1 - 0.017 15.0 2.5 0.017 15.0 2.5 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK45435.1 - 0.054 14.0 1.4 0.054 14.0 1.4 3.2 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 KKK45435.1 - 0.1 13.5 6.6 0.83 10.5 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK45435.1 - 2.6 8.7 16.4 2.7 8.6 3.0 2.8 2 1 2 4 4 3 0 4Fe-4S dicluster domain SNAP PF14938.6 KKK45440.1 - 3.4e-05 23.4 2.3 0.0033 16.9 0.7 2.5 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KKK45440.1 - 6.9e-05 23.1 0.1 1 9.7 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK45440.1 - 0.00014 21.7 0.9 1.3 9.3 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KKK45440.1 - 0.00021 21.0 1.4 1.5 8.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK45440.1 - 0.0016 18.3 2.0 4 7.7 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat NSF PF02071.20 KKK45440.1 - 0.0037 17.7 2.4 3.1 9.0 0.6 3.9 4 0 0 4 4 4 1 Aromatic-di-Alanine (AdAR) repeat TPR_10 PF13374.6 KKK45440.1 - 0.033 14.0 0.0 0.3 11.0 0.0 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 KKK45440.1 - 0.043 13.9 2.3 0.69 10.0 0.1 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KKK45440.1 - 0.051 13.8 1.1 2 8.9 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat Prefoldin PF02996.17 KKK45440.1 - 0.13 12.2 4.6 0.52 10.2 0.1 3.2 3 0 0 3 3 3 0 Prefoldin subunit Radical_SAM PF04055.21 KKK45441.1 - 9.3e-16 58.7 0.1 8.6e-15 55.5 0.1 2.5 3 0 0 3 3 3 1 Radical SAM superfamily B12-binding PF02310.19 KKK45441.1 - 2e-14 53.7 0.0 5e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain Fer4_12 PF13353.6 KKK45441.1 - 0.014 15.7 0.4 0.039 14.2 0.2 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK45441.1 - 0.12 12.6 1.7 0.26 11.4 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain TPR_1 PF00515.28 KKK45443.1 - 8.1e-16 57.1 0.2 4e-09 35.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK45443.1 - 2.7e-13 48.9 0.1 2.7e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KKK45443.1 - 1.8e-12 46.4 0.0 2.4e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KKK45443.1 - 1.6e-09 37.3 0.0 1.1e-06 28.2 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 KKK45443.1 - 3.8e-07 30.3 0.1 0.0012 19.1 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KKK45443.1 - 7e-06 26.4 0.0 0.032 15.0 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK45443.1 - 2.5e-05 24.0 0.1 0.0055 16.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KKK45443.1 - 2.6e-05 24.7 0.0 3.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3856 PF12968.7 KKK45443.1 - 7.3e-05 22.9 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 KKK45443.1 - 0.0017 17.3 0.1 0.0018 17.3 0.1 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_17 PF13431.6 KKK45443.1 - 0.003 17.8 0.7 1.3 9.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat MAS20 PF02064.15 KKK45443.1 - 0.003 17.6 0.1 0.0042 17.2 0.1 1.3 1 0 0 1 1 1 1 MAS20 protein import receptor TPR_6 PF13174.6 KKK45443.1 - 0.0039 17.7 0.0 0.25 12.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KKK45443.1 - 0.018 15.7 0.0 0.043 14.5 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KKK45443.1 - 0.026 14.6 0.2 8.7 6.5 0.0 2.5 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 KKK45443.1 - 0.027 14.3 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 KKK45443.1 - 0.028 14.2 0.1 0.11 12.4 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5113) TPR_15 PF13429.6 KKK45443.1 - 0.068 12.4 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 KKK45443.1 - 0.072 13.3 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_8 PF13855.6 KKK45446.1 - 1.3e-15 56.9 9.7 2.3e-09 36.8 2.5 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KKK45446.1 - 4.1e-11 42.9 16.3 2e-06 28.0 3.6 5.4 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK45446.1 - 0.00013 22.0 13.0 0.041 14.4 0.7 6.3 6 1 0 6 6 6 1 Leucine Rich Repeat Radical_SAM PF04055.21 KKK45447.1 - 1.6e-14 54.6 0.0 3.6e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK45447.1 - 8.3e-07 29.4 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KKK45447.1 - 3.7e-06 27.1 0.0 3.7e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain SPASM PF13186.6 KKK45447.1 - 0.0029 18.1 1.6 0.01 16.3 1.6 2.0 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain MFS_1 PF07690.16 KKK45448.1 - 3.2e-19 69.1 54.7 2.4e-13 49.8 45.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_target_1 PF15179.6 KKK45448.1 - 0.07 13.0 3.7 1.4 8.8 0.3 2.5 2 0 0 2 2 2 0 Myc target protein 1 HTH_5 PF01022.20 KKK45449.1 - 9.4e-12 44.6 0.4 2.3e-11 43.4 0.3 1.7 1 1 1 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KKK45449.1 - 2.2e-11 43.6 0.0 3.1e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 KKK45449.1 - 4.6e-07 29.6 0.0 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 KKK45449.1 - 2.2e-06 27.5 0.2 5.8e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 MarR family HTH_24 PF13412.6 KKK45449.1 - 3e-06 26.7 0.5 9.1e-06 25.1 0.5 1.9 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 KKK45449.1 - 9.2e-06 25.8 0.1 1.6e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Winged helix DNA-binding domain HTH_27 PF13463.6 KKK45449.1 - 0.00027 21.4 0.1 0.00075 20.0 0.0 1.8 1 1 1 2 2 2 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 KKK45449.1 - 0.00038 20.4 0.3 0.0015 18.5 0.2 1.9 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 KKK45449.1 - 0.0028 17.5 0.2 0.017 15.0 0.0 2.0 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 KKK45449.1 - 0.0057 16.6 0.2 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 KKK45449.1 - 0.0078 16.1 0.3 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 HTH domain DUF2513 PF10711.9 KKK45449.1 - 0.0078 16.5 0.2 0.014 15.7 0.2 1.5 1 1 0 1 1 1 1 Hypothetical protein (DUF2513) Fe_dep_repress PF01325.19 KKK45449.1 - 0.047 13.9 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF2250 PF10007.9 KKK45449.1 - 0.048 13.8 0.2 0.18 11.9 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) RPA_C PF08784.11 KKK45449.1 - 0.081 13.6 0.1 0.14 12.8 0.1 1.5 1 1 0 1 1 1 0 Replication protein A C terminal Sigma70_r4_2 PF08281.12 KKK45449.1 - 0.098 12.3 0.3 0.2 11.4 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Rio2_N PF09202.11 KKK45449.1 - 0.2 11.9 1.4 13 6.0 0.2 2.3 1 1 1 2 2 2 0 Rio2, N-terminal DUF2156 PF09924.9 KKK45453.1 - 5.1e-11 42.1 0.1 8.7e-11 41.4 0.1 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) PhnJ PF06007.11 KKK45453.1 - 0.16 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ NosD PF05048.13 KKK45454.1 - 3.8e-40 137.7 74.8 6.1e-28 97.7 39.9 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK45454.1 - 9.7e-26 90.5 80.5 3.4e-15 56.2 35.5 3.3 1 1 2 3 3 3 3 Right handed beta helix region DUF806 PF05657.11 KKK45454.1 - 6.9 7.2 11.3 0.6 10.6 2.5 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF806) TCR_zetazeta PF11628.8 KKK45457.1 - 8.9 6.1 9.3 7.6 6.3 0.2 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain PK PF00224.21 KKK45458.1 - 1.3e-112 376.2 6.4 1.8e-112 375.7 6.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KKK45458.1 - 3.1e-18 66.1 0.0 9e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KKK45458.1 - 0.00076 18.7 0.2 0.0053 15.9 0.1 2.2 3 0 0 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KKK45458.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain RibD_C PF01872.17 KKK45458.1 - 0.036 13.9 0.0 0.087 12.6 0.0 1.4 1 1 0 1 1 1 0 RibD C-terminal domain DUF3006 PF11213.8 KKK45458.1 - 0.32 11.2 2.6 3.3 8.0 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3006) TMEM237 PF15383.6 KKK45460.1 - 0.066 12.3 0.1 0.067 12.3 0.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 SLATT_4 PF18186.1 KKK45461.1 - 0.00085 19.0 4.5 0.0011 18.6 4.3 1.4 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 4 TMEM208_SND2 PF05620.11 KKK45461.1 - 0.018 14.9 1.1 0.047 13.5 1.1 1.6 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Arv1 PF04161.13 KKK45461.1 - 0.077 13.2 2.9 0.12 12.5 2.9 1.3 1 0 0 1 1 1 0 Arv1-like family Ribosomal_S8 PF00410.19 KKK45461.1 - 0.17 11.8 2.7 0.34 10.9 2.7 1.5 1 0 0 1 1 1 0 Ribosomal protein S8 CCDC-167 PF15188.6 KKK45461.1 - 6.3 7.2 8.4 19 5.7 5.9 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 RDD PF06271.12 KKK45462.1 - 0.0047 17.1 6.6 0.75 10.0 0.1 3.2 3 0 0 3 3 3 2 RDD family Ost5 PF05251.12 KKK45462.1 - 0.015 15.5 4.6 0.055 13.7 0.1 3.5 4 1 0 4 4 4 0 Oligosaccharyltransferase subunit 5 Coa1 PF08695.10 KKK45462.1 - 0.05 13.3 2.8 3.3 7.5 0.0 3.1 3 0 0 3 3 3 0 Cytochrome oxidase complex assembly protein 1 Halogen_Hydrol PF10112.9 KKK45462.1 - 0.15 12.0 2.5 0.69 9.9 0.6 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein NnrU PF07298.11 KKK45462.1 - 0.18 11.3 4.2 0.15 11.6 0.2 2.5 2 1 0 3 3 3 0 NnrU protein DctQ PF04290.12 KKK45462.1 - 0.36 10.8 4.9 8.9 6.2 0.0 3.4 3 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component MscS_TM PF12794.7 KKK45462.1 - 0.5 9.2 5.7 0.091 11.6 0.7 2.2 2 1 1 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 LapA_dom PF06305.11 KKK45462.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.6 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain DDE_Tnp_1 PF01609.21 KKK45463.1 - 2.1e-09 37.4 2.4 4.2e-09 36.4 1.1 2.1 2 1 0 2 2 2 1 Transposase DDE domain DUF2299 PF10061.9 KKK45464.1 - 3.4e-17 62.5 0.0 5.3e-17 61.9 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) DUF211 PF02680.14 KKK45465.1 - 2.9e-24 85.0 0.2 3.3e-24 84.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized ArCR, COG1888 Cortex-I_coil PF09304.10 KKK45465.1 - 0.061 13.5 0.0 0.067 13.4 0.0 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil HAD_2 PF13419.6 KKK45466.1 - 9.2e-29 100.8 2.7 1.2e-28 100.4 2.7 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK45466.1 - 3e-15 57.1 0.2 2e-13 51.1 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KKK45466.1 - 1.8e-11 44.0 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 KKK45466.1 - 4.8e-05 23.2 8.9 0.0043 16.8 4.3 2.6 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HTH_26 PF13443.6 KKK45466.1 - 0.0026 18.1 0.1 0.17 12.4 0.0 2.8 2 1 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain NIF PF03031.18 KKK45466.1 - 0.0093 15.7 0.4 0.06 13.1 0.4 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3251 PF11622.8 KKK45466.1 - 0.019 14.6 0.2 0.033 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Arm_APC_u3 PF16629.5 KKK45466.1 - 0.11 12.1 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Armadillo-associated region on APC LigT_PEase PF02834.16 KKK45467.1 - 1.3e-14 54.1 0.1 2.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 KKK45467.1 - 1e-11 45.1 4.0 1.5e-11 44.6 4.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KKK45467.1 - 2e-07 31.1 0.0 2.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.12 KKK45467.1 - 0.00098 18.5 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Coronavirus NS2A protein MatP_C PF17414.2 KKK45467.1 - 9.5 6.5 7.3 30 4.9 0.1 2.6 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain 2-Hacid_dh_C PF02826.19 KKK45468.1 - 4.9e-39 133.5 0.0 6.5e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KKK45468.1 - 1.6e-09 37.5 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KKK45468.1 - 1.7e-08 34.8 0.0 3.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KKK45468.1 - 0.033 14.7 0.0 0.066 13.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-FCS PF06467.14 KKK45469.1 - 0.001 19.0 1.0 0.0018 18.2 1.0 1.4 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif HNOBA PF07701.14 KKK45469.1 - 0.02 14.3 0.3 0.025 14.0 0.3 1.1 1 0 0 1 1 1 0 Heme NO binding associated VKG_Carbox PF05090.14 KKK45469.1 - 0.27 10.0 0.5 0.3 9.9 0.5 1.0 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DUF5409 PF17421.2 KKK45470.1 - 0.043 14.5 2.0 0.16 12.7 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5409) Sulfatase PF00884.23 KKK45473.1 - 1.5e-36 126.4 0.0 8.9e-36 123.8 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KKK45473.1 - 1.2e-09 38.2 0.0 4.8e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KKK45473.1 - 0.013 14.2 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KKK45473.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF2555 PF10742.9 KKK45473.1 - 0.089 12.6 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) DUF5362 PF17319.2 KKK45474.1 - 6 6.8 6.7 1 9.3 2.2 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5362) Glyco_hydro_2_C PF02836.17 KKK45475.1 - 1.5e-104 349.4 1.5 2.2e-104 348.8 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KKK45475.1 - 2.2e-67 227.2 0.0 3.5e-67 226.6 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KKK45475.1 - 4.3e-50 169.9 4.5 4.4e-50 169.9 2.6 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KKK45475.1 - 5.7e-22 78.0 0.0 1.4e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KKK45475.1 - 6.5e-15 55.8 0.0 1.7e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KKK45475.1 - 0.0072 16.9 0.1 0.018 15.6 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Picorna_P3A PF06363.11 KKK45475.1 - 0.07 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Picornaviridae P3A protein Fer4 PF00037.27 KKK45476.1 - 8.8e-07 28.5 15.4 1.8e-05 24.4 1.9 3.1 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK45476.1 - 3.5e-05 23.9 11.8 3.5e-05 23.9 11.8 2.4 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45476.1 - 5.7e-05 24.0 0.6 5.7e-05 24.0 0.6 2.9 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 KKK45476.1 - 0.00019 21.3 2.0 0.00019 21.3 2.0 3.3 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK45476.1 - 0.00033 21.2 0.4 0.00033 21.2 0.4 2.8 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK45476.1 - 0.00039 20.5 24.0 0.0024 18.0 13.4 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45476.1 - 0.00092 19.3 12.0 0.00092 19.3 12.0 2.7 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45476.1 - 0.0038 17.2 2.3 0.0038 17.2 2.3 3.5 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KKK45476.1 - 0.041 14.4 5.3 0.041 14.4 5.3 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK45476.1 - 0.073 14.0 4.5 0.073 14.0 4.5 3.7 4 1 0 4 4 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 KKK45476.1 - 0.95 10.2 7.9 0.35 11.6 0.4 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain Aminotran_3 PF00202.21 KKK45477.1 - 1.3e-70 238.2 0.0 1.7e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III HATPase_c PF02518.26 KKK45479.1 - 3.1e-17 63.1 1.4 7.8e-17 61.8 0.3 2.1 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 KKK45479.1 - 1.4e-05 25.0 0.0 4.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_5 PF14501.6 KKK45479.1 - 0.0012 18.8 2.9 0.0012 18.8 2.9 2.5 2 1 0 2 2 2 1 GHKL domain HATPase_c_2 PF13581.6 KKK45479.1 - 0.0029 17.5 0.0 0.0099 15.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_8 PF13188.7 KKK45479.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 KKK45479.1 - 0.021 15.1 0.5 0.12 12.7 0.5 2.3 1 1 0 1 1 1 0 PAS domain ZinT PF09223.11 KKK45479.1 - 0.22 11.4 2.6 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment DDE_Tnp_1 PF01609.21 KKK45480.1 - 1.2e-08 34.9 0.0 1.9e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Spc7 PF08317.11 KKK45481.1 - 2.7e-10 39.6 44.5 5.7e-07 28.7 19.3 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein ADIP PF11559.8 KKK45481.1 - 1.4e-09 38.3 46.4 4.2e-05 23.7 9.5 3.1 1 1 2 3 3 3 3 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 KKK45481.1 - 6.2e-09 36.2 34.9 3.2e-05 24.1 8.8 2.5 1 1 2 3 3 3 3 Fibrinogen alpha/beta chain family SlyX PF04102.12 KKK45481.1 - 2.9e-08 34.2 27.7 0.0023 18.5 1.3 5.5 1 1 4 5 5 5 2 SlyX Pox_A_type_inc PF04508.12 KKK45481.1 - 5e-08 32.4 5.9 0.022 14.6 0.0 4.9 4 1 0 4 4 4 2 Viral A-type inclusion protein repeat Lebercilin PF15619.6 KKK45481.1 - 2.3e-07 30.7 40.6 8.3e-05 22.3 15.8 3.3 1 1 2 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.8 KKK45481.1 - 2.9e-07 30.4 51.0 0.0024 17.8 11.6 4.6 1 1 3 5 5 5 2 TATA element modulatory factor 1 DNA binding HrpB7 PF09486.10 KKK45481.1 - 3.7e-07 30.6 17.2 0.017 15.5 3.8 3.2 1 1 2 3 3 3 2 Bacterial type III secretion protein (HrpB7) CALCOCO1 PF07888.11 KKK45481.1 - 7.9e-07 28.3 39.9 0.00078 18.4 10.0 2.9 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like PKcGMP_CC PF16808.5 KKK45481.1 - 8.8e-07 28.7 7.4 0.13 12.1 0.0 5.7 5 1 1 6 6 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase MscS_porin PF12795.7 KKK45481.1 - 9e-07 28.7 52.0 0.00025 20.7 13.3 2.7 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain ATG16 PF08614.11 KKK45481.1 - 9.1e-07 29.3 47.5 0.0044 17.3 12.5 3.3 1 1 2 3 3 3 3 Autophagy protein 16 (ATG16) Filament PF00038.21 KKK45481.1 - 1.2e-06 28.3 35.6 0.0018 17.9 8.2 3.1 1 1 2 3 3 3 2 Intermediate filament protein Fez1 PF06818.15 KKK45481.1 - 1.5e-06 28.8 35.2 0.052 14.0 8.5 3.1 1 1 2 3 3 3 3 Fez1 FliJ PF02050.16 KKK45481.1 - 3e-06 27.4 25.4 0.0031 17.7 3.7 3.1 1 1 2 3 3 3 3 Flagellar FliJ protein UPF0242 PF06785.11 KKK45481.1 - 5.2e-06 26.7 39.2 3.5e-05 24.0 22.3 2.6 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KKK45481.1 - 5.9e-06 25.6 36.0 0.0031 16.7 9.6 3.1 1 1 2 3 3 3 3 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 KKK45481.1 - 1.3e-05 24.3 37.1 3.1e-05 23.1 37.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF812) DUF3552 PF12072.8 KKK45481.1 - 2.5e-05 23.8 34.4 0.11 11.8 6.3 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) CENP-F_leu_zip PF10473.9 KKK45481.1 - 3.7e-05 23.8 41.6 0.00019 21.4 22.6 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 KKK45481.1 - 4e-05 23.0 38.2 0.00034 19.9 24.3 3.0 1 1 1 2 2 2 1 HAP1 N-terminal conserved region AAA_13 PF13166.6 KKK45481.1 - 7.6e-05 21.6 35.6 0.00028 19.7 35.3 1.8 1 1 0 1 1 1 1 AAA domain HMMR_N PF15905.5 KKK45481.1 - 8.5e-05 22.2 42.5 0.002 17.7 25.0 3.0 1 1 2 3 3 3 3 Hyaluronan mediated motility receptor N-terminal DUF5082 PF16888.5 KKK45481.1 - 0.00014 22.1 37.9 0.017 15.4 21.4 4.1 1 1 3 4 4 4 3 Domain of unknown function (DUF5082) DUF1664 PF07889.12 KKK45481.1 - 0.00016 21.7 29.8 0.00018 21.5 4.9 3.7 2 1 2 4 4 3 2 Protein of unknown function (DUF1664) HOOK PF05622.12 KKK45481.1 - 0.00021 19.6 39.9 0.0076 14.5 18.3 2.1 1 1 1 2 2 2 2 HOOK protein Exonuc_VII_L PF02601.15 KKK45481.1 - 0.00021 21.0 28.8 0.0086 15.7 13.2 2.1 1 1 1 2 2 2 2 Exonuclease VII, large subunit BicD PF09730.9 KKK45481.1 - 0.00029 19.4 31.5 0.0029 16.1 11.6 2.0 1 1 1 2 2 2 2 Microtubule-associated protein Bicaudal-D DUF4201 PF13870.6 KKK45481.1 - 0.00033 20.4 36.2 0.087 12.6 10.2 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF4201) DUF724 PF05266.14 KKK45481.1 - 0.00034 20.5 3.7 0.00034 20.5 3.7 3.3 1 1 1 3 3 3 1 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 KKK45481.1 - 0.00034 20.7 45.1 0.073 13.1 8.2 3.6 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein COG2 PF06148.11 KKK45481.1 - 0.00036 20.6 25.7 0.026 14.6 2.3 3.9 1 1 2 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KKK45481.1 - 0.00041 20.7 35.5 0.51 10.8 4.7 6.3 3 1 2 6 6 6 1 Flagella accessory protein C (FlaC) Leu_zip PF15294.6 KKK45481.1 - 0.00046 19.8 18.4 0.00046 19.8 18.4 2.1 1 1 1 2 2 2 1 Leucine zipper Baculo_PEP_C PF04513.12 KKK45481.1 - 0.00063 19.8 50.8 0.035 14.2 19.0 3.8 1 1 2 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Cast PF10174.9 KKK45481.1 - 0.00077 17.8 37.7 0.0075 14.6 24.2 2.2 1 1 1 2 2 2 2 RIM-binding protein of the cytomatrix active zone DUF4686 PF15742.5 KKK45481.1 - 0.00085 18.6 39.2 0.78 8.8 39.2 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4686) Med9 PF07544.13 KKK45481.1 - 0.00096 19.2 28.0 0.81 9.8 1.0 4.5 2 1 2 4 4 4 1 RNA polymerase II transcription mediator complex subunit 9 DHR10 PF18595.1 KKK45481.1 - 0.001 19.1 39.3 0.06 13.4 7.1 4.6 1 1 3 4 4 4 1 Designed helical repeat protein 10 domain IFT57 PF10498.9 KKK45481.1 - 0.0011 18.0 38.5 0.082 11.9 13.8 3.1 1 1 2 3 3 3 2 Intra-flagellar transport protein 57 YscO PF07321.12 KKK45481.1 - 0.0014 18.6 27.7 0.069 13.1 3.4 3.8 1 1 2 3 3 3 2 Type III secretion protein YscO FPP PF05911.11 KKK45481.1 - 0.0015 16.9 43.4 0.015 13.6 43.4 1.9 1 1 0 1 1 1 1 Filament-like plant protein, long coiled-coil Golgin_A5 PF09787.9 KKK45481.1 - 0.0017 17.9 37.3 0.069 12.6 9.6 2.1 1 1 1 2 2 2 2 Golgin subfamily A member 5 KASH_CCD PF14662.6 KKK45481.1 - 0.0017 18.2 38.6 0.024 14.5 21.4 2.2 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH DUF4200 PF13863.6 KKK45481.1 - 0.002 18.5 32.8 0.1 13.0 9.3 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF4200) GAS PF13851.6 KKK45481.1 - 0.002 17.5 40.5 0.012 15.0 29.0 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.19 KKK45481.1 - 0.0025 15.7 35.6 0.0043 14.9 26.7 2.0 1 1 0 1 1 1 1 Myosin tail Bacillus_HBL PF05791.11 KKK45481.1 - 0.0029 17.4 8.9 0.0029 17.4 8.9 3.5 1 1 2 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) Sec8_exocyst PF04048.14 KKK45481.1 - 0.0031 17.4 35.1 0.041 13.8 11.2 3.8 1 1 2 3 3 3 1 Sec8 exocyst complex component specific domain Prefoldin PF02996.17 KKK45481.1 - 0.0034 17.3 39.9 0.35 10.8 1.7 5.4 1 1 2 5 5 5 3 Prefoldin subunit MAD PF05557.13 KKK45481.1 - 0.0035 15.8 16.1 0.0035 15.8 16.1 1.9 1 1 1 2 2 2 1 Mitotic checkpoint protein CC2-LZ PF16516.5 KKK45481.1 - 0.0046 17.3 31.8 0.052 13.9 5.6 4.6 1 1 2 4 4 4 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TolA_bind_tri PF16331.5 KKK45481.1 - 0.0051 16.9 26.8 1.1 9.4 2.1 4.4 1 1 2 4 4 4 1 TolA binding protein trimerisation EzrA PF06160.12 KKK45481.1 - 0.0052 15.0 34.6 0.027 12.7 30.3 2.7 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DUF3450 PF11932.8 KKK45481.1 - 0.0057 16.0 40.2 0.055 12.8 7.6 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) DUF4472 PF14739.6 KKK45481.1 - 0.0058 17.3 34.0 0.41 11.4 4.0 4.0 1 1 3 4 4 4 2 Domain of unknown function (DUF4472) Rab5-bind PF09311.11 KKK45481.1 - 0.0088 15.5 35.1 0.49 9.7 7.0 3.1 1 1 2 3 3 3 2 Rabaptin-like protein Tropomyosin PF00261.20 KKK45481.1 - 0.0093 15.4 37.4 0.009 15.4 21.4 2.9 1 1 1 2 2 2 2 Tropomyosin Prefoldin_2 PF01920.20 KKK45481.1 - 0.0093 15.9 42.9 0.84 9.6 12.4 6.0 2 1 3 6 6 6 1 Prefoldin subunit DUF4407 PF14362.6 KKK45481.1 - 0.0094 15.3 35.5 0.27 10.6 17.3 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) MT PF12777.7 KKK45481.1 - 0.01 14.9 5.3 0.01 14.9 5.3 3.6 1 1 1 3 3 3 0 Microtubule-binding stalk of dynein motor TACC_C PF05010.14 KKK45481.1 - 0.013 15.3 30.6 0.011 15.5 13.6 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TMF_TATA_bd PF12325.8 KKK45481.1 - 0.013 15.7 38.3 0.97 9.7 11.2 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding MAP65_ASE1 PF03999.12 KKK45481.1 - 0.016 13.9 27.7 0.027 13.2 27.7 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) CEP63 PF17045.5 KKK45481.1 - 0.022 14.7 29.4 0.27 11.1 27.1 2.1 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Tektin PF03148.14 KKK45481.1 - 0.028 13.2 34.9 0.062 12.0 21.5 2.9 1 1 2 3 3 3 0 Tektin family GrpE PF01025.19 KKK45481.1 - 0.031 14.0 35.0 0.18 11.4 6.7 4.1 1 1 3 4 4 4 0 GrpE DUF745 PF05335.13 KKK45481.1 - 0.031 14.0 38.9 0.067 12.9 10.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Spc29 PF17082.5 KKK45481.1 - 0.032 14.1 19.8 4 7.2 11.2 3.0 1 1 1 2 2 2 0 Spindle Pole Component 29 Tmemb_cc2 PF10267.9 KKK45481.1 - 0.034 13.3 31.6 0.49 9.5 17.4 2.8 1 1 2 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein Tropomyosin_1 PF12718.7 KKK45481.1 - 0.057 13.6 46.3 4.3 7.5 7.2 3.6 1 1 2 3 3 3 0 Tropomyosin like PI3K_P85_iSH2 PF16454.5 KKK45481.1 - 0.068 12.8 26.2 1.4 8.5 3.1 3.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Sec2p PF06428.11 KKK45481.1 - 0.075 13.0 40.1 4.9 7.2 1.0 5.2 1 1 4 5 5 5 0 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 KKK45481.1 - 0.075 12.4 33.5 1.3 8.3 11.8 3.0 1 1 1 2 2 2 0 FAM76 protein DUF16 PF01519.16 KKK45481.1 - 0.086 13.3 31.3 1.6 9.3 8.5 4.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 Val_tRNA-synt_C PF10458.9 KKK45481.1 - 0.095 13.0 0.8 0.095 13.0 0.8 4.8 4 1 1 5 5 4 0 Valyl tRNA synthetase tRNA binding arm APG6_N PF17675.1 KKK45481.1 - 0.099 13.2 44.9 2.6 8.6 19.8 3.5 1 1 1 2 2 1 0 Apg6 coiled-coil region THOC7 PF05615.13 KKK45481.1 - 0.11 12.8 31.8 2.2 8.6 6.9 4.1 1 1 3 4 4 3 0 Tho complex subunit 7 Laminin_II PF06009.12 KKK45481.1 - 0.13 12.3 38.1 11 6.0 13.9 3.8 1 1 2 3 3 3 0 Laminin Domain II DUF4763 PF15960.5 KKK45481.1 - 0.14 11.4 30.5 0.81 8.9 12.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) HIP1_clath_bdg PF16515.5 KKK45481.1 - 0.15 12.7 44.8 1.1 9.9 4.8 4.2 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMPIT PF07851.13 KKK45481.1 - 0.16 11.2 32.1 0.3 10.3 8.5 3.0 1 1 2 3 3 3 0 TMPIT-like protein DUF3584 PF12128.8 KKK45481.1 - 0.2 9.1 37.1 0.15 9.5 19.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.11 KKK45481.1 - 0.24 12.0 32.7 0.11 13.0 7.8 3.5 1 1 1 2 2 1 0 Syntaxin 6, N-terminal DUF641 PF04859.12 KKK45481.1 - 0.25 11.7 31.4 11 6.3 1.0 4.5 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) COG5 PF10392.9 KKK45481.1 - 0.26 11.5 29.9 0.77 9.9 4.7 3.5 1 1 2 3 3 3 0 Golgi transport complex subunit 5 DUF2203 PF09969.9 KKK45481.1 - 0.26 12.0 22.2 3 8.6 4.9 3.7 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) Macoilin PF09726.9 KKK45481.1 - 0.27 9.7 30.0 1.6 7.2 30.0 1.8 1 1 0 1 1 1 0 Macoilin family Mce4_CUP1 PF11887.8 KKK45481.1 - 0.3 10.5 24.5 0.29 10.6 12.6 2.3 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Occludin_ELL PF07303.13 KKK45481.1 - 0.47 11.2 18.5 7 7.4 2.4 4.0 1 1 2 3 3 3 0 Occludin homology domain DUF948 PF06103.11 KKK45481.1 - 0.47 10.7 34.7 0.39 11.0 3.7 4.2 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 KKK45481.1 - 0.51 10.1 40.1 0.089 12.6 2.5 6.2 2 1 4 6 6 6 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 KKK45481.1 - 0.66 10.2 39.5 4.1 7.6 16.0 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 PspA_IM30 PF04012.12 KKK45481.1 - 0.77 9.3 37.1 29 4.1 26.3 3.5 1 1 1 2 2 2 0 PspA/IM30 family Nsp1_C PF05064.13 KKK45481.1 - 0.77 9.6 33.9 0.43 10.4 6.2 4.1 1 1 3 4 4 4 0 Nsp1-like C-terminal region NPV_P10 PF05531.12 KKK45481.1 - 0.77 10.3 36.9 6.8 7.2 4.8 4.9 2 1 3 5 5 4 0 Nucleopolyhedrovirus P10 protein EspB_PE PF18625.1 KKK45481.1 - 0.78 10.2 15.9 0.63 10.5 2.0 3.4 2 1 1 3 3 3 0 ESX-1 secreted protein B PE domain Seryl_tRNA_N PF02403.22 KKK45481.1 - 0.79 10.0 39.9 5.8 7.2 4.4 4.3 1 1 3 4 4 3 0 Seryl-tRNA synthetase N-terminal domain CCDC144C PF14915.6 KKK45481.1 - 0.86 8.7 41.4 0.6 9.2 15.8 2.6 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region APG17 PF04108.12 KKK45481.1 - 0.86 8.6 35.9 3.5e+02 0.0 35.9 2.2 1 1 0 1 1 1 0 Autophagy protein Apg17 KELK PF15796.5 KKK45481.1 - 0.93 10.0 27.8 1 9.8 7.3 3.8 1 1 3 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CREPT PF16566.5 KKK45481.1 - 0.94 9.6 26.0 10 6.2 5.2 3.5 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour OmpH PF03938.14 KKK45481.1 - 1.1 9.6 35.9 0.29 11.5 3.9 3.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) PRKG1_interact PF15898.5 KKK45481.1 - 1.2 10.1 38.9 4.9 8.1 9.1 4.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain End3 PF12761.7 KKK45481.1 - 1.2 9.3 35.4 1.7 8.8 15.9 2.5 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 HemX PF04375.14 KKK45481.1 - 1.2 8.3 41.6 6.8 5.9 7.8 3.2 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4618 PF15397.6 KKK45481.1 - 1.3 8.4 36.4 2.8 7.3 10.6 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DASH_Dam1 PF08653.10 KKK45481.1 - 1.5 8.7 21.7 2.9 7.8 2.8 5.4 2 2 4 6 6 4 0 DASH complex subunit Dam1 KxDL PF10241.9 KKK45481.1 - 1.7 9.0 31.2 0.89 9.9 2.5 4.4 1 1 4 5 5 5 0 Uncharacterized conserved protein Ax_dynein_light PF10211.9 KKK45481.1 - 1.8 8.5 36.7 0.052 13.5 8.2 4.1 1 1 3 4 4 4 0 Axonemal dynein light chain SKA1 PF07160.12 KKK45481.1 - 1.9 8.3 31.9 7.1 6.4 7.9 3.4 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 LegC3_N PF18654.1 KKK45481.1 - 2.1 7.5 30.2 3.4 6.8 5.8 2.9 1 1 1 2 2 2 0 LegC3 N-terminal coiled-coil domain COMMD1_N PF17221.3 KKK45481.1 - 2.1 8.7 18.5 0.35 11.2 0.5 3.7 1 1 3 4 4 2 0 COMMD1 N-terminal domain MPS2 PF17060.5 KKK45481.1 - 2.3 7.4 24.1 4.6 6.4 16.1 2.7 1 1 1 2 2 2 0 Monopolar spindle protein 2 MIP-T3_C PF17749.1 KKK45481.1 - 2.3 8.2 30.6 6.6 6.7 7.4 3.8 1 1 2 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Spectrin PF00435.21 KKK45481.1 - 2.5 8.6 31.7 12 6.5 6.3 3.6 1 1 1 3 3 3 0 Spectrin repeat DUF4455 PF14643.6 KKK45481.1 - 3 6.4 30.3 0.32 9.6 6.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4455) PKHD_C PF18331.1 KKK45481.1 - 3.1 7.9 4.7 5.5 7.1 0.1 3.5 5 0 0 5 5 2 0 PKHD-type hydroxylase C-terminal domain DivIVA PF05103.13 KKK45481.1 - 3.6 7.7 37.2 0.87 9.7 9.5 3.4 1 1 2 3 3 3 0 DivIVA protein Gp58 PF07902.11 KKK45481.1 - 3.7 5.7 26.0 0.13 10.6 3.2 2.5 1 1 1 2 2 2 0 gp58-like protein BRE1 PF08647.11 KKK45481.1 - 3.7 7.7 43.8 1.6 8.9 5.4 4.2 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase Tup_N PF08581.10 KKK45481.1 - 3.9 7.9 24.3 5.2 7.4 6.2 4.9 1 1 5 6 6 6 0 Tup N-terminal BLOC1_2 PF10046.9 KKK45481.1 - 3.9 7.8 37.5 23 5.4 11.5 4.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LXG PF04740.12 KKK45481.1 - 3.9 7.1 36.4 2.3 7.9 20.1 3.1 1 1 2 3 3 3 0 LXG domain of WXG superfamily Taxilin PF09728.9 KKK45481.1 - 4.3 6.4 37.0 0.45 9.7 16.3 2.3 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF848 PF05852.11 KKK45481.1 - 4.6 7.3 29.3 2.1 8.4 1.9 3.2 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) PI_PP_I PF18363.1 KKK45481.1 - 4.8 7.4 13.5 2.3 8.4 5.1 3.0 1 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain Ribosomal_S15 PF00312.22 KKK45481.1 - 4.9 7.4 8.3 2.2 8.6 0.4 3.7 2 1 2 4 4 2 0 Ribosomal protein S15 MerR-DNA-bind PF09278.11 KKK45481.1 - 5.2 7.7 15.2 28 5.3 2.0 5.3 1 1 5 6 6 4 0 MerR, DNA binding DUF4795 PF16043.5 KKK45481.1 - 5.6 6.5 37.1 9.4 5.8 2.8 3.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Snapin_Pallidin PF14712.6 KKK45481.1 - 5.9 7.4 32.1 83 3.7 8.5 4.3 1 1 0 2 2 1 0 Snapin/Pallidin LPP PF04728.13 KKK45481.1 - 5.9 7.4 34.6 2.6 8.5 1.0 5.7 3 3 2 5 5 5 0 Lipoprotein leucine-zipper USP8_interact PF08941.10 KKK45481.1 - 6.1 6.6 23.0 13 5.6 1.5 4.0 1 1 1 2 2 1 0 USP8 interacting FUSC PF04632.12 KKK45481.1 - 6.3 5.2 12.5 1.6 7.1 5.0 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Csm1_N PF18504.1 KKK45481.1 - 6.7 7.1 40.5 9.6 6.6 4.6 6.1 1 1 4 6 6 6 0 Csm1 N-terminal domain HAUS-augmin3 PF14932.6 KKK45481.1 - 6.8 6.2 42.3 1.3 8.5 8.7 3.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 WEMBL PF05701.11 KKK45481.1 - 7 5.2 39.7 26 3.3 39.7 1.7 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Nup88 PF10168.9 KKK45481.1 - 7.4 4.3 28.1 0.57 7.9 14.5 2.1 1 1 2 3 3 3 0 Nuclear pore component YjcZ PF13990.6 KKK45481.1 - 7.6 5.8 22.0 3.1 7.1 2.6 3.4 2 1 2 4 4 3 0 YjcZ-like protein DUF1515 PF07439.11 KKK45481.1 - 7.9 6.6 8.8 6.6 6.8 1.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) PCRF PF03462.18 KKK45481.1 - 8 6.3 33.4 2.9 7.7 8.7 3.0 1 1 3 4 4 4 0 PCRF domain AATF-Che1 PF13339.6 KKK45481.1 - 8.5 7.1 36.7 2.1 9.1 10.6 3.2 1 1 1 2 2 1 0 Apoptosis antagonizing transcription factor DLP_helical PF18709.1 KKK45481.1 - 9.3 5.3 28.7 1.2 8.3 3.6 3.4 1 1 2 3 3 2 0 Dynamin-like helical domain RPW8 PF05659.11 KKK45481.1 - 9.7 5.9 18.4 7.9 6.2 1.3 4.0 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Hexapep_2 PF14602.6 KKK45482.1 - 2.1e-08 33.7 0.2 5.2e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KKK45482.1 - 2.8e-05 23.7 1.6 0.0017 18.0 0.1 2.8 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep PF00132.24 KKK45483.1 - 2.1e-08 33.6 1.0 0.0022 17.7 0.0 2.6 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KKK45483.1 - 6.7e-06 25.8 1.6 0.048 13.4 0.0 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Metallophos PF00149.28 KKK45484.1 - 1.5e-20 74.6 3.1 1.5e-15 58.2 1.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK45484.1 - 9.5e-15 55.2 0.0 1.2e-10 41.8 0.0 2.6 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Virulence_RhuM PF13310.6 KKK45484.1 - 0.036 13.3 0.3 0.29 10.3 0.1 2.2 2 0 0 2 2 2 0 Virulence protein RhuM family ThiS PF02597.20 KKK45485.1 - 0.00091 19.8 0.0 0.0012 19.4 0.0 1.2 1 0 0 1 1 1 1 ThiS family Tma16 PF11176.8 KKK45485.1 - 0.042 13.7 0.2 0.054 13.4 0.2 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Urm1 PF09138.11 KKK45485.1 - 0.05 14.0 0.2 0.055 13.8 0.2 1.2 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Gtr1_RagA PF04670.12 KKK45486.1 - 5e-23 81.7 1.4 7.3e-23 81.1 1.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK45486.1 - 1.8e-14 53.6 0.0 2.8e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK45486.1 - 4.4e-08 33.2 0.0 9.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK45486.1 - 2.7e-05 23.7 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK45486.1 - 0.0039 17.4 0.0 0.0084 16.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK45486.1 - 0.033 13.8 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Ras family Ribosomal_S25 PF03297.15 KKK45487.1 - 2.2e-06 27.8 0.5 2.3e-06 27.8 0.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FeoC PF09012.10 KKK45487.1 - 0.066 13.3 0.1 0.084 13.0 0.1 1.1 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_28 PF13518.6 KKK45487.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C4pol PF14260.6 KKK45490.1 - 0.026 15.0 5.1 0.026 15.0 5.1 2.5 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta MRP-L28 PF09812.9 KKK45490.1 - 0.037 14.2 7.7 0.054 13.6 7.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Acatn PF13000.7 KKK45490.1 - 0.19 10.2 0.6 0.21 10.0 0.6 1.0 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 MSP7_C PF12948.7 KKK45491.1 - 0.0083 16.8 0.5 0.0083 16.8 0.5 2.1 1 1 1 2 2 2 1 MSP7-like protein C-terminal domain Ribosomal_L33 PF00471.20 KKK45491.1 - 0.18 12.3 3.9 1.9 9.0 0.1 2.9 2 0 0 2 2 2 0 Ribosomal protein L33 Glucosamine_iso PF01182.20 KKK45493.1 - 1.1e-11 45.0 0.0 1.9e-05 24.7 0.0 2.4 2 1 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PGM_PMM_I PF02878.16 KKK45494.1 - 9.8e-33 112.8 0.6 2.5e-32 111.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KKK45494.1 - 7.2e-21 74.5 0.0 1.2e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KKK45494.1 - 2.8e-20 72.9 0.0 7.4e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KKK45494.1 - 2e-07 31.1 0.0 6.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1031 PF06275.11 KKK45496.1 - 0.076 13.3 0.0 0.09 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Abhydrolase_1 PF00561.20 KKK45500.1 - 2.2e-17 63.6 0.0 7.3e-16 58.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK45500.1 - 1.3e-08 35.8 0.0 1.6e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK45500.1 - 1.6e-06 27.5 0.0 2.7e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK45500.1 - 0.0014 17.4 0.0 0.0029 16.3 0.0 1.4 1 1 0 1 1 1 1 Ndr family ADH_zinc_N PF00107.26 KKK45502.1 - 1.7e-25 89.5 0.4 2.7e-25 88.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK45502.1 - 7.8e-23 80.4 0.1 2.1e-22 79.0 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KKK45502.1 - 3.1e-09 38.0 0.1 4.8e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KKK45502.1 - 0.00044 19.6 0.3 0.00084 18.7 0.3 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KKK45502.1 - 0.0026 17.1 0.9 0.0043 16.4 0.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KKK45502.1 - 0.018 14.5 0.3 0.041 13.3 0.3 1.6 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 KKK45502.1 - 0.024 14.5 0.3 0.04 13.8 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1906 PF08924.11 KKK45502.1 - 0.033 14.3 0.1 0.091 12.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) Eno-Rase_NADH_b PF12242.8 KKK45502.1 - 0.08 12.7 0.7 0.19 11.5 0.7 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PIN PF01850.21 KKK45504.1 - 1.4e-08 35.3 0.0 1.9e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 PIN domain L_lactis_ph-MCP PF06673.11 KKK45504.1 - 0.02 13.9 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein KH_10 PF17905.1 KKK45504.1 - 0.11 12.9 0.1 0.63 10.5 0.0 1.9 2 0 0 2 2 2 0 GLD-3 KH domain 5 HHH_3 PF12836.7 KKK45505.1 - 0.061 13.6 0.2 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif LID PF17916.1 KKK45507.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 LIM interaction domain (LID) CBFD_NFYB_HMF PF00808.23 KKK45508.1 - 3e-09 37.0 0.0 3.4e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KKK45508.1 - 1.4e-06 28.2 0.0 1.6e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KKK45508.1 - 0.0003 20.9 0.0 0.00035 20.6 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KKK45508.1 - 0.0018 18.3 0.0 0.0022 18.1 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KKK45508.1 - 0.0028 18.0 0.1 0.0032 17.8 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 KKK45508.1 - 0.013 16.0 0.0 0.015 15.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TAF PF02969.17 KKK45508.1 - 0.052 13.7 0.1 0.056 13.6 0.1 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KKK45508.1 - 0.1 13.0 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 CENP-S protein Cation_efflux PF01545.21 KKK45510.1 - 1.4e-10 41.3 21.2 1.4e-10 41.3 21.2 2.5 2 1 0 2 2 2 1 Cation efflux family HTH_45 PF14947.6 KKK45510.1 - 0.016 15.2 2.7 4 7.5 0.3 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DUF3679 PF12438.8 KKK45510.1 - 0.53 10.0 2.5 25 4.7 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) DUF3188 PF11384.8 KKK45510.1 - 5.9 6.7 9.4 5.8 6.7 1.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Cpta_toxin PF07254.12 KKK45511.1 - 0.0057 16.6 1.5 0.0068 16.4 1.5 1.0 1 0 0 1 1 1 1 Membrane-bound toxin component of toxin-antitoxin system SirB PF04247.12 KKK45511.1 - 0.15 12.1 4.7 0.17 12.0 4.7 1.1 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB Cation_ATPase_C PF00689.21 KKK45511.1 - 0.35 10.6 6.0 0.42 10.3 6.0 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF4131 PF13567.6 KKK45511.1 - 0.58 9.8 2.8 0.64 9.6 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 KKK45511.1 - 4.2 6.0 5.9 4.7 5.9 5.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Baculo_11_kDa PF06143.11 KKK45511.1 - 7.8 6.2 10.3 5.6 6.6 2.7 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family HemY_N PF07219.13 KKK45511.1 - 9.2 6.5 9.6 12 6.1 3.0 2.0 1 1 1 2 2 2 0 HemY protein N-terminus Ras PF00071.22 KKK45512.1 - 1.3e-28 99.6 0.0 1.5e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK45512.1 - 5.2e-23 81.5 0.0 8.7e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK45512.1 - 4.9e-08 32.6 0.0 6.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK45512.1 - 0.00015 21.2 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KKK45512.1 - 0.094 11.9 2.3 0.96 8.5 0.1 2.3 2 1 1 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KKK45512.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase EamA PF00892.20 KKK45513.1 - 5.7e-33 114.0 38.8 1.8e-16 60.6 8.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KKK45513.1 - 4.3e-07 29.5 19.1 2.2e-06 27.1 4.4 2.4 1 1 1 2 2 2 2 Purine nucleobase transmembrane transport TPT PF03151.16 KKK45513.1 - 0.003 17.0 17.2 0.034 13.5 9.6 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family PNTB PF02233.16 KKK45513.1 - 6.9 5.5 10.6 0.53 9.2 4.6 2.0 2 1 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Succ_CoA_lig PF13607.6 KKK45514.1 - 1.9e-28 99.0 0.0 3.5e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK45514.1 - 2.2e-07 31.3 0.0 7e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain DZR PF12773.7 KKK45515.1 - 0.0059 16.6 1.1 0.009 16.0 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 KKK45515.1 - 0.009 16.0 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KKK45515.1 - 0.018 15.3 0.2 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_4 PF13717.6 KKK45515.1 - 0.061 13.2 1.4 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 KKK45515.1 - 0.098 12.4 5.3 0.97 9.2 1.0 2.3 1 1 1 2 2 2 0 A2L zinc ribbon domain Cys_rich_KTR PF14205.6 KKK45515.1 - 0.1 12.4 1.9 0.28 11.0 1.9 1.7 1 1 0 1 1 1 0 Cysteine-rich KTR Lig_chan PF00060.26 KKK45515.1 - 0.14 12.0 0.8 0.38 10.6 0.8 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel Zn-ribbon_8 PF09723.10 KKK45515.1 - 0.21 11.7 1.8 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.14 KKK45515.1 - 0.28 11.2 1.9 0.87 9.6 1.9 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 KKK45515.1 - 0.65 9.5 5.6 3.2 7.3 5.8 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK45515.1 - 1.5 9.7 7.0 0.65 10.8 2.5 2.4 1 1 1 2 2 2 0 zinc-ribbon family Rxt3 PF08642.10 KKK45516.1 - 0.12 13.1 0.0 0.21 12.4 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 NIPSNAP PF07978.13 KKK45518.1 - 8.2e-05 22.8 0.0 0.0033 17.6 0.0 2.1 2 0 0 2 2 2 1 NIPSNAP UCR_Fe-S_N PF10399.9 KKK45518.1 - 0.085 12.2 0.3 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal GSH-S_ATP PF02955.16 KKK45519.1 - 2.5e-51 173.6 0.1 3.5e-51 173.1 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 KKK45519.1 - 2.7e-27 95.3 0.0 3.9e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 KKK45519.1 - 2.6e-13 50.0 0.0 8.1e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 KKK45519.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp TTL PF03133.15 KKK45519.1 - 0.0091 15.2 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family DUF4446 PF14584.6 KKK45519.1 - 0.078 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) GshA PF08886.11 KKK45520.1 - 5.5e-123 410.5 1.2 6.4e-123 410.3 1.2 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase Longin PF13774.6 KKK45521.1 - 0.078 13.0 0.1 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 Regulated-SNARE-like domain Lipase_GDSL_lke PF16255.5 KKK45522.1 - 0.08 12.3 1.6 0.15 11.4 1.6 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Cnd1 PF12717.7 KKK45523.1 - 0.00045 20.3 0.9 0.00045 20.3 0.9 2.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KKK45523.1 - 0.001 19.1 0.1 12 6.5 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KKK45523.1 - 0.0066 16.8 0.1 0.15 12.4 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats RTP1_C1 PF10363.9 KKK45523.1 - 0.014 15.6 0.1 0.014 15.6 0.1 2.8 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF5039 PF16442.5 KKK45524.1 - 1.1 8.7 4.9 10 5.6 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) Arf PF00025.21 KKK45525.1 - 2.9e-09 36.6 0.1 5.8e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK45525.1 - 1.9e-08 34.5 0.0 5.1e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK45525.1 - 2e-07 30.8 0.0 4.9e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KKK45525.1 - 2.9e-06 27.3 0.1 0.032 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KKK45525.1 - 0.0027 17.1 0.1 0.027 13.9 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KKK45525.1 - 0.033 13.9 1.3 0.088 12.5 0.0 2.5 4 0 0 4 4 4 0 AAA domain Peptidase_M32 PF02074.15 KKK45526.1 - 2.3e-178 593.9 0.7 2.6e-178 593.8 0.7 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase CDP-OH_P_transf PF01066.21 KKK45527.1 - 1.1e-09 38.9 3.4 1.1e-09 38.9 3.4 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zinc_ribbon_2 PF13240.6 KKK45528.1 - 2.1e-14 52.7 16.0 8.2e-08 31.7 3.8 2.3 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 KKK45528.1 - 9.2e-12 44.8 12.2 1.3e-11 44.3 12.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK45528.1 - 5e-10 40.0 9.2 3.4e-05 24.5 1.2 2.2 2 0 0 2 2 2 2 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK45528.1 - 4.6e-07 29.0 16.0 0.00095 18.5 2.6 3.3 1 1 3 4 4 4 3 zinc-ribbon domain UPF0547 PF10571.9 KKK45528.1 - 6.1e-06 26.2 13.4 0.0015 18.5 1.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 KKK45528.1 - 1.7e-05 24.7 16.1 0.00035 20.5 5.5 2.3 1 1 1 2 2 2 2 zinc-ribbons zf-C3HC4_3 PF13920.6 KKK45528.1 - 0.0014 18.4 10.5 0.093 12.6 2.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.16 KKK45528.1 - 0.0026 17.6 12.6 0.0071 16.2 1.4 3.0 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit HypA PF01155.19 KKK45528.1 - 0.0035 17.3 12.9 0.078 13.0 2.6 2.3 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 KKK45528.1 - 0.0044 16.6 6.9 0.9 9.3 0.1 2.6 2 1 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.11 KKK45528.1 - 0.0059 16.7 12.1 0.28 11.4 2.2 2.5 1 1 1 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 KKK45528.1 - 0.0081 16.3 13.4 0.11 12.7 1.5 3.4 1 1 2 3 3 3 1 Zinc ribbon domain DUF35_N PF12172.8 KKK45528.1 - 0.013 15.3 6.9 0.5 10.3 0.8 2.8 3 0 0 3 3 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) SelP_C PF04593.14 KKK45528.1 - 0.018 15.1 4.2 0.023 14.7 4.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, C terminal region YhfH PF14149.6 KKK45528.1 - 0.023 14.7 16.2 0.077 13.0 0.1 4.1 1 1 3 4 4 4 0 YhfH-like protein DNA_ligase_ZBD PF03119.16 KKK45528.1 - 0.052 13.6 4.6 2.8 8.1 0.9 2.7 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1272 PF06906.11 KKK45528.1 - 0.06 13.5 9.4 0.093 12.8 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Nudix_N_2 PF14803.6 KKK45528.1 - 0.25 11.3 19.0 0.42 10.6 3.8 3.5 3 1 1 4 4 3 0 Nudix N-terminal Zn_ribbon_17 PF17120.5 KKK45528.1 - 0.35 10.5 7.2 1.3 8.7 1.1 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Zn_ribbon_SprT PF17283.2 KKK45528.1 - 0.38 10.7 11.9 2 8.4 1.9 4.0 5 1 0 5 5 3 0 SprT-like zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK45528.1 - 0.41 10.6 13.0 0.31 11.0 3.3 3.1 1 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-RING_4 PF14570.6 KKK45528.1 - 0.46 10.3 10.8 1.9 8.3 2.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cytochrom_c3_2 PF14537.6 KKK45528.1 - 0.5 10.9 11.3 6.1 7.4 11.1 2.0 1 1 0 1 1 1 0 Cytochrome c3 ADK_lid PF05191.14 KKK45528.1 - 0.53 10.3 11.5 10 6.2 4.4 3.7 2 1 1 3 3 2 0 Adenylate kinase, active site lid MqsA_antitoxin PF15731.5 KKK45528.1 - 0.58 10.3 4.9 1.2 9.2 0.8 2.5 1 1 1 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA TackOD1 PF18551.1 KKK45528.1 - 0.7 9.5 11.5 0.6 9.7 1.7 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-C4_Topoisom PF01396.19 KKK45528.1 - 0.72 9.7 11.1 1.9 8.3 2.3 3.5 1 1 2 3 3 3 0 Topoisomerase DNA binding C4 zinc finger TF_Zn_Ribbon PF08271.12 KKK45528.1 - 0.83 9.2 13.5 0.11 12.0 3.0 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding zf-BED PF02892.15 KKK45528.1 - 0.95 9.5 10.5 2.2e+02 2.0 8.8 3.2 1 1 1 2 2 2 0 BED zinc finger zf-RRN7 PF11781.8 KKK45528.1 - 1.3 8.7 10.0 28 4.5 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DpnI PF06044.12 KKK45528.1 - 2.2 7.9 6.6 5.8 6.5 0.4 2.6 1 1 1 2 2 2 0 Dam-replacing family Ogr_Delta PF04606.12 KKK45528.1 - 2.4 8.2 7.8 11 6.0 2.1 2.8 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DUF1610 PF07754.11 KKK45528.1 - 3.3 7.8 11.2 26 4.9 4.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) zf-C2HC5 PF06221.13 KKK45528.1 - 4.3 7.4 11.5 0.21 11.6 0.9 3.0 1 1 2 3 3 3 0 Putative zinc finger motif, C2HC5-type C1_1 PF00130.22 KKK45528.1 - 4.9 7.1 12.2 44 4.1 5.9 3.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cys_rich_CPXG PF14255.6 KKK45528.1 - 7.2 6.6 14.4 14 5.6 1.9 4.0 4 1 0 4 4 3 0 Cysteine-rich CPXCG GARS_A PF01071.19 KKK45529.1 - 5.9e-51 173.0 0.7 8.3e-51 172.5 0.7 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KKK45529.1 - 8.2e-22 77.8 0.3 2.3e-21 76.4 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 KKK45529.1 - 1.6e-09 37.9 0.0 3.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.6 KKK45529.1 - 0.00059 19.5 0.0 0.0088 15.6 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.10 KKK45529.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain HEAT_2 PF13646.6 KKK45530.1 - 5.3e-11 42.8 0.3 4.1e-08 33.5 0.2 2.1 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 KKK45530.1 - 1.8e-06 28.0 0.5 1.8 9.5 0.1 3.4 3 0 0 3 3 3 3 PBS lyase HEAT-like repeat Pro_dh-DNA_bdg PF14850.6 KKK45530.1 - 0.022 15.3 0.2 0.26 11.8 0.0 2.3 1 1 2 3 3 3 0 DNA-binding domain of Proline dehydrogenase DUF615 PF04751.14 KKK45530.1 - 0.068 13.1 1.1 0.17 11.8 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF615) HAD PF12710.7 KKK45531.1 - 2.3e-06 28.1 0.0 0.002 18.6 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK45531.1 - 3.8e-05 23.6 1.7 3.9e-05 23.5 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KKK45531.1 - 0.0035 17.7 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK45531.1 - 0.029 14.5 0.6 24 5.0 0.0 3.4 2 1 2 4 4 4 0 Haloacid dehalogenase-like hydrolase NIF PF03031.18 KKK45531.1 - 0.057 13.2 0.1 0.48 10.2 0.0 2.3 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase PAS PF00989.25 KKK45532.1 - 5.5e-35 119.8 7.2 1.5e-17 63.6 0.0 6.4 6 0 0 6 6 6 5 PAS fold PAS_4 PF08448.10 KKK45532.1 - 2.9e-34 117.6 0.0 1.5e-10 41.3 0.0 5.0 5 1 0 5 5 5 3 PAS fold PAS_9 PF13426.7 KKK45532.1 - 4.5e-32 110.4 25.9 2.5e-14 53.4 0.5 6.5 7 0 0 7 7 7 5 PAS domain HATPase_c PF02518.26 KKK45532.1 - 2.9e-22 79.3 0.1 8e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KKK45532.1 - 1.6e-20 73.1 0.0 2.6e-08 34.0 0.0 4.6 5 0 0 5 5 4 3 PAS fold PAS_8 PF13188.7 KKK45532.1 - 4.5e-12 45.7 0.5 1.5e-06 28.1 0.0 4.2 5 0 0 5 5 4 2 PAS domain HisKA PF00512.25 KKK45532.1 - 2.3e-10 40.4 0.2 2.3e-10 40.4 0.2 3.4 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 KKK45532.1 - 2.7e-07 30.7 0.1 0.018 15.2 0.0 3.1 2 0 0 2 2 2 2 PAS domain PAS_7 PF12860.7 KKK45532.1 - 2.2e-06 27.8 3.5 0.064 13.4 0.1 5.0 5 0 0 5 5 5 2 PAS fold HATPase_c_3 PF13589.6 KKK45532.1 - 0.027 14.3 0.0 0.1 12.4 0.0 2.0 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 KKK45532.1 - 0.39 11.3 9.1 2.5 8.7 0.0 5.3 5 1 2 7 7 6 0 PAS domain TINF2_N PF14973.6 KKK45532.1 - 0.54 10.6 0.0 0.54 10.6 0.0 5.3 6 0 0 6 6 6 0 TERF1-interacting nuclear factor 2 N-terminus DUF4349 PF14257.6 KKK45532.1 - 0.55 9.6 6.0 2 7.8 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) LMBR1 PF04791.16 KKK45532.1 - 0.85 8.5 18.9 0.096 11.6 3.5 3.0 3 1 0 3 3 3 0 LMBR1-like membrane protein Holin_BhlA PF10960.8 KKK45532.1 - 3.9 7.5 14.5 17 5.4 0.2 4.8 4 0 0 4 4 3 0 BhlA holin family HNOBA PF07701.14 KKK45532.1 - 7.3 6.0 13.2 1 8.7 3.0 3.3 2 2 0 2 2 2 0 Heme NO binding associated Topoisom_bac PF01131.20 KKK45533.1 - 1.9e-85 287.4 0.8 2.5e-85 287.0 0.8 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KKK45533.1 - 1.2e-09 38.3 0.1 4.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Toprim domain HTH_45 PF14947.6 KKK45533.1 - 0.0022 17.9 0.3 0.012 15.6 0.3 2.3 1 0 0 1 1 1 1 Winged helix-turn-helix ApoLp-III PF07464.11 KKK45533.1 - 0.035 14.2 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Ephrin_rec_like PF07699.13 KKK45533.1 - 0.15 11.9 2.2 0.58 10.0 1.0 2.3 2 0 0 2 2 2 0 Putative ephrin-receptor like Actin PF00022.19 KKK45535.1 - 8.1e-88 294.8 0.0 1.5e-86 290.6 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KKK45535.1 - 0.0024 16.7 0.0 0.39 9.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Pyr_redox_2 PF07992.14 KKK45541.1 - 5.9e-12 45.4 0.1 7.2e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KKK45541.1 - 1.1e-11 44.5 1.8 3.1e-08 33.1 1.9 2.0 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KKK45541.1 - 1.5e-10 40.8 1.5 7e-06 25.5 0.4 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK45541.1 - 3.9e-10 39.7 0.0 3.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK45541.1 - 9.2e-10 37.8 0.6 4.2e-07 29.0 0.6 2.0 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 KKK45541.1 - 3.3e-07 29.8 0.6 4.5e-07 29.3 0.2 1.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KKK45541.1 - 9.5e-07 28.7 1.8 9.5e-05 22.1 1.4 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK45541.1 - 2.3e-06 27.7 0.1 3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KKK45541.1 - 1.9e-05 23.9 3.9 4.1e-05 22.8 1.0 2.0 1 1 1 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KKK45541.1 - 0.00053 20.5 1.5 0.0042 17.6 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KKK45541.1 - 0.00067 18.8 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KKK45541.1 - 0.0013 18.1 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KKK45541.1 - 0.0021 17.4 0.5 0.003 16.8 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 KKK45541.1 - 0.005 16.0 0.2 1.1 8.3 0.1 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 KKK45541.1 - 0.0094 15.5 0.1 0.019 14.6 0.0 1.4 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Amino_oxidase PF01593.24 KKK45541.1 - 0.016 14.5 0.1 0.035 13.4 0.1 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KKK45541.1 - 0.018 13.9 0.5 0.024 13.5 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 KKK45541.1 - 0.13 12.2 0.1 0.16 12.0 0.1 1.3 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fer2_BFD PF04324.15 KKK45542.1 - 2.8e-15 56.4 1.6 5.9e-15 55.4 1.6 1.6 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain DAO PF01266.24 KKK45542.1 - 3e-10 40.2 0.0 4.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Antifungal_pept PF11410.8 KKK45542.1 - 0.15 12.0 0.8 0.27 11.2 0.8 1.4 1 0 0 1 1 1 0 Antifungal peptide TbpB_B_D PF01298.18 KKK45544.1 - 0.67 10.3 3.9 1.3 9.4 1.1 2.5 2 1 1 3 3 3 0 C-lobe and N-lobe beta barrels of Tf-binding protein B FeoA PF04023.14 KKK45545.1 - 3.3e-16 59.3 0.1 3.8e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 FeoA domain FeoB_N PF02421.18 KKK45546.1 - 5.1e-61 204.8 0.2 9.2e-61 203.9 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Gate PF07670.14 KKK45546.1 - 5.8e-19 68.4 18.5 7.9e-11 42.2 2.0 3.0 4 0 0 4 4 4 2 Nucleoside recognition MMR_HSR1 PF01926.23 KKK45546.1 - 1.1e-18 67.4 0.0 3e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_Cyto PF17910.1 KKK45546.1 - 2.9e-16 59.8 2.2 5.6e-16 58.9 2.2 1.5 1 0 0 1 1 1 1 FeoB cytosolic helical domain FeoB_C PF07664.12 KKK45546.1 - 3.6e-13 49.0 0.4 3.6e-13 49.0 0.4 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B C terminus GTP_EFTU PF00009.27 KKK45546.1 - 2.4e-05 24.0 1.4 0.0002 20.9 0.1 2.9 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KKK45546.1 - 0.00012 21.5 0.0 0.00035 20.0 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF2972 PF11186.8 KKK45546.1 - 8.4 6.3 12.5 0.45 10.4 6.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) Beta-lactamase PF00144.24 KKK45547.1 - 7.4e-57 193.1 0.0 9.4e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Oxidored_FMN PF00724.20 KKK45548.1 - 6e-64 216.5 0.0 2e-56 191.7 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 KKK45548.1 - 0.0003 20.3 0.0 0.0008 18.9 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein ComA PF02679.15 KKK45548.1 - 0.0095 15.4 0.1 2.7 7.4 0.0 2.3 2 0 0 2 2 2 2 (2R)-phospho-3-sulfolactate synthase (ComA) DeoC PF01791.9 KKK45548.1 - 0.021 14.5 0.0 8.7 5.9 0.0 2.6 2 1 0 2 2 2 0 DeoC/LacD family aldolase Dus PF01207.17 KKK45548.1 - 0.18 10.9 0.0 15 4.5 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Lactamase_B_2 PF12706.7 KKK45549.1 - 3.4e-18 65.9 0.1 4.4e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KKK45549.1 - 7.7e-07 29.3 1.0 3.6e-06 27.1 0.4 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily FAM92 PF06730.11 KKK45550.1 - 6.9e-09 35.5 14.9 8.1e-09 35.2 14.9 1.0 1 0 0 1 1 1 1 FAM92 protein DUF4398 PF14346.6 KKK45550.1 - 0.00017 22.2 3.7 0.00017 22.2 3.7 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4398) DUF1664 PF07889.12 KKK45550.1 - 0.019 15.0 16.4 0.024 14.7 0.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4363 PF14276.6 KKK45550.1 - 0.91 9.7 17.3 1 9.5 8.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) ApoO PF09769.9 KKK45550.1 - 1.3 8.9 7.5 25 4.8 0.1 3.1 2 1 0 2 2 2 0 Apolipoprotein O Flagellin_C PF00700.21 KKK45550.1 - 1.5 9.3 7.5 3.7 8.0 0.1 3.3 3 1 1 4 4 4 0 Bacterial flagellin C-terminal helical region Baculo_PEP_C PF04513.12 KKK45550.1 - 2.5 8.2 12.7 2 8.4 3.5 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Asp-B-Hydro_N PF05279.11 KKK45550.1 - 3 7.9 22.3 3.6 7.6 22.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3391 PF11871.8 KKK45550.1 - 6.8 7.2 12.2 4.4 7.9 9.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF2120 PF09893.9 KKK45550.1 - 7.8 6.6 16.8 24 5.1 8.7 3.0 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF2564 PF10819.8 KKK45550.1 - 7.8 7.0 14.8 0.38 11.2 2.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2564) Exonuc_VII_L PF02601.15 KKK45550.1 - 9 5.8 13.3 17 4.8 13.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit zinc_ribbon_12 PF11331.8 KKK45553.1 - 0.025 14.4 0.6 2.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain Peptidase_S74 PF13884.6 KKK45554.1 - 0.023 15.0 0.2 0.18 12.2 0.2 2.1 1 1 0 1 1 1 0 Chaperone of endosialidase Peptidase_M20 PF01546.28 KKK45557.1 - 8.2e-13 48.5 0.0 1.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK45557.1 - 2.4e-09 37.1 0.1 5e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 KKK45557.1 - 5.2e-08 32.3 0.0 0.0026 16.8 0.0 2.4 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 KKK45557.1 - 0.00064 19.5 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 zf-CCHC_6 PF15288.6 KKK45558.1 - 0.0013 18.5 0.2 0.0013 18.5 0.2 2.4 2 0 0 2 2 2 1 Zinc knuckle Nha1_C PF08619.10 KKK45558.1 - 0.0021 17.4 2.9 0.0027 17.0 2.9 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Imm31 PF15591.6 KKK45558.1 - 0.032 14.1 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 31 Zn-ribbon_8 PF09723.10 KKK45558.1 - 0.032 14.3 5.2 1.6 8.9 0.9 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-IS66 PF13005.7 KKK45558.1 - 0.054 13.9 8.5 2.5 8.6 1.2 3.8 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Nudix_N_2 PF14803.6 KKK45558.1 - 0.075 13.0 0.6 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.6 KKK45558.1 - 0.12 11.8 2.5 2.9 7.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_9 PF00759.19 KKK45558.1 - 0.19 11.1 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 zinc_ribbon_2 PF13240.6 KKK45558.1 - 0.19 11.5 3.4 4.9 7.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 KKK45558.1 - 0.24 11.4 3.3 0.62 10.0 2.7 1.9 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KKK45558.1 - 0.29 11.2 2.6 0.87 9.6 2.6 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2HE PF16278.5 KKK45558.1 - 0.31 11.5 3.9 0.41 11.1 0.7 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-HIT PF04438.16 KKK45558.1 - 0.67 9.9 4.8 2.1 8.3 0.9 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-CCHC PF00098.23 KKK45558.1 - 0.92 9.7 5.5 6 7.1 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Rubredoxin_2 PF18073.1 KKK45558.1 - 2.8 7.7 5.6 8.1 6.3 1.0 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Metallophos_2 PF12850.7 KKK45559.1 - 7.8e-20 71.7 0.0 9.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KKK45559.1 - 1.2e-07 32.5 2.4 1.4e-06 28.9 2.4 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase KxDL PF10241.9 KKK45560.1 - 0.0043 17.3 2.4 0.0043 17.3 2.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein T3SS_needle_F PF09392.10 KKK45560.1 - 0.0051 17.0 4.6 0.0059 16.8 4.6 1.0 1 0 0 1 1 1 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF2229 PF09989.9 KKK45561.1 - 8.6e-46 156.3 0.0 1.2e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 CoA enzyme activase uncharacterised domain (DUF2229) HGD-D PF06050.13 KKK45561.1 - 7.5e-05 22.6 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component Toxin_trans PF07952.12 KKK45561.1 - 0.0027 16.8 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain Acyltransferase PF01553.21 KKK45562.1 - 1.8e-49 166.8 0.0 1.1e-24 86.6 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase LRR_4 PF12799.7 KKK45564.1 - 6.4e-25 86.8 56.5 5.8e-09 36.1 9.2 5.8 1 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK45564.1 - 4.5e-17 61.6 47.5 5.1e-07 29.3 6.2 4.9 2 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KKK45564.1 - 7.4e-13 48.4 26.0 3.2e-07 30.0 7.7 3.3 1 1 2 3 3 3 3 Leucine-rich repeat UvrB_inter PF17757.1 KKK45564.1 - 0.0084 16.3 2.2 16 5.7 0.1 4.2 1 1 2 4 4 4 1 UvrB interaction domain TbpB_C PF17483.2 KKK45564.1 - 0.0099 16.2 8.4 0.17 12.3 0.1 3.7 1 1 4 5 5 5 1 C-lobe handle domain of Tf-binding protein B UB2H PF14814.6 KKK45564.1 - 0.012 15.6 5.0 29 4.8 0.1 4.9 2 1 3 5 5 5 0 Bifunctional transglycosylase second domain LRR_2 PF07723.13 KKK45564.1 - 0.034 14.8 0.8 19 6.1 0.0 4.4 3 1 2 5 5 5 0 Leucine Rich Repeat LRR_5 PF13306.6 KKK45564.1 - 0.054 13.5 12.5 0.089 12.8 5.4 2.4 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KKK45564.1 - 0.097 12.8 0.7 0.097 12.8 0.7 6.8 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 KKK45564.1 - 0.22 12.2 34.2 1.1 10.1 1.1 7.6 6 3 1 7 7 7 0 Leucine Rich Repeat FAD_binding_1 PF00667.20 KKK45565.1 - 0.076 12.6 0.3 0.21 11.2 0.2 1.7 1 1 1 2 2 2 0 FAD binding domain RPA_interact_C PF14768.6 KKK45566.1 - 0.0046 17.5 0.1 0.0046 17.5 0.1 1.1 1 0 0 1 1 1 1 Replication protein A interacting C-terminal zf-RRPl_C4 PF17026.5 KKK45566.1 - 0.028 14.5 0.3 0.034 14.2 0.3 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type NCD3G PF07562.14 KKK45566.1 - 0.035 14.1 1.5 0.054 13.5 1.5 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR DNA_RNApol_7kD PF03604.13 KKK45566.1 - 0.072 12.8 3.1 0.11 12.2 3.1 1.2 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.7 KKK45566.1 - 0.086 12.8 1.6 0.13 12.2 1.6 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.13 KKK45566.1 - 0.13 12.0 0.6 0.13 12.0 0.6 1.6 2 0 0 2 2 2 0 InsA N-terminal domain Fer4_9 PF13187.6 KKK45567.1 - 0.014 15.5 3.3 0.03 14.5 3.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45567.1 - 0.031 14.1 2.0 0.069 13.0 2.0 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_10 PF13237.6 KKK45567.1 - 0.042 14.0 2.0 0.12 12.6 2.0 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF3029 PF11230.8 KKK45567.1 - 0.14 10.5 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Fer4_4 PF12800.7 KKK45567.1 - 2 9.1 10.3 0.1 13.1 4.4 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK45567.1 - 3 8.1 9.8 0.14 12.3 3.7 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain WCCH PF03716.14 KKK45571.1 - 0.076 12.7 2.4 0.12 12.0 2.4 1.4 1 0 0 1 1 1 0 WCCH motif Pyr_redox_2 PF07992.14 KKK45572.1 - 3.1e-18 66.0 0.0 3.8e-17 62.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KKK45572.1 - 2.7e-06 27.9 10.0 0.0015 19.1 1.5 3.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Pyr_redox PF00070.27 KKK45572.1 - 3.2e-06 27.6 0.5 4.4e-05 24.0 0.1 2.5 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK45572.1 - 5.2e-06 26.6 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_6 PF12837.7 KKK45572.1 - 2.3e-05 24.2 12.6 0.00026 20.9 4.0 3.4 4 0 0 4 4 2 2 4Fe-4S binding domain FAD_oxidored PF12831.7 KKK45572.1 - 5.2e-05 22.8 0.0 8.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4 PF00037.27 KKK45572.1 - 6e-05 22.7 4.6 6e-05 22.7 4.6 4.1 5 0 0 5 5 4 2 4Fe-4S binding domain GIDA PF01134.22 KKK45572.1 - 0.00013 21.1 0.1 0.0034 16.5 0.0 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KKK45572.1 - 0.0003 20.5 0.1 0.0011 18.6 0.1 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Fer4_10 PF13237.6 KKK45572.1 - 0.00031 20.8 10.0 0.00078 19.5 1.0 3.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45572.1 - 0.00048 20.0 2.7 0.00048 20.0 2.7 3.6 5 0 0 5 5 2 2 4Fe-4S binding domain HI0933_like PF03486.14 KKK45572.1 - 0.00092 18.0 0.0 0.0082 14.9 0.1 2.1 1 1 1 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KKK45572.1 - 0.00095 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KKK45572.1 - 0.0028 17.7 0.3 2 8.4 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KKK45572.1 - 0.0033 16.7 0.2 0.17 11.1 0.1 2.5 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK45572.1 - 0.0036 16.6 0.0 0.0076 15.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KKK45572.1 - 0.0047 16.3 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain Fer4_15 PF13459.6 KKK45572.1 - 0.0074 17.0 0.4 0.0074 17.0 0.4 2.1 2 0 0 2 2 1 1 4Fe-4S single cluster domain Lycopene_cycl PF05834.12 KKK45572.1 - 0.0078 15.3 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Fer4_8 PF13183.6 KKK45572.1 - 0.01 16.3 5.5 0.095 13.2 0.5 3.5 4 0 0 4 4 4 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45572.1 - 0.015 15.4 0.3 0.015 15.4 0.3 3.5 4 0 0 4 4 3 0 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 KKK45572.1 - 0.018 14.3 0.3 0.03 13.6 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Fer4_16 PF13484.6 KKK45572.1 - 0.08 13.9 12.2 0.3 12.1 0.4 3.8 4 0 0 4 4 3 0 4Fe-4S double cluster binding domain Amino_oxidase PF01593.24 KKK45572.1 - 0.21 10.8 0.0 0.55 9.5 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Fer4_13 PF13370.6 KKK45572.1 - 0.33 11.5 6.5 0.25 11.9 2.7 2.7 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_9 PF13187.6 KKK45572.1 - 0.42 10.8 19.0 0.085 13.0 4.6 3.3 3 1 0 3 3 3 0 4Fe-4S dicluster domain SCIFF PF13165.6 KKK45572.1 - 3.2 7.8 11.2 0.27 11.2 1.0 3.0 4 0 0 4 4 2 0 Six-cysteine peptide SCIFF Fer4_17 PF13534.6 KKK45572.1 - 4.7 7.8 14.5 1.6 9.3 4.9 3.5 3 1 0 3 3 3 0 4Fe-4S dicluster domain PAS PF00989.25 KKK45575.1 - 3.1e-35 120.6 0.0 1.3e-10 41.3 0.0 4.2 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 KKK45575.1 - 1.1e-30 106.0 0.9 1.3e-09 38.2 0.0 4.6 4 1 0 4 4 4 4 PAS domain PAS_8 PF13188.7 KKK45575.1 - 6.7e-30 102.6 0.0 1.3e-07 31.5 0.0 4.3 4 0 0 4 4 4 4 PAS domain PAS_3 PF08447.12 KKK45575.1 - 2.9e-28 98.0 0.0 1.5e-14 54.1 0.0 5.0 5 0 0 5 5 5 3 PAS fold PAS_4 PF08448.10 KKK45575.1 - 3.2e-15 56.3 0.0 9.9e-05 22.6 0.0 5.3 4 2 0 4 4 4 3 PAS fold PAS_7 PF12860.7 KKK45575.1 - 2.5e-07 30.9 0.1 0.37 11.0 0.0 4.9 4 2 0 4 4 4 2 PAS fold PAS_11 PF14598.6 KKK45575.1 - 0.00055 20.0 0.0 0.028 14.5 0.0 2.7 1 1 2 3 3 3 1 PAS domain DUF2959 PF11172.8 KKK45575.1 - 0.009 16.2 2.3 7.1 6.7 0.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2959) Holin_BhlA PF10960.8 KKK45575.1 - 0.023 14.7 10.2 0.43 10.6 0.2 3.6 3 0 0 3 3 3 0 BhlA holin family HAS-barrel PF09378.10 KKK45575.1 - 0.41 10.8 2.9 0.95 9.7 0.2 2.8 3 0 0 3 3 3 0 HAS barrel domain 3H PF02829.14 KKK45575.1 - 0.43 10.9 0.0 0.43 10.9 0.0 2.7 3 1 1 4 4 4 0 3H domain HsdM_N PF12161.8 KKK45575.1 - 0.43 11.2 4.9 0.76 10.4 0.3 3.0 2 1 0 2 2 2 0 HsdM N-terminal domain Beta-lactamase PF00144.24 KKK45576.1 - 2.1e-44 152.1 0.0 2.6e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KKK45576.1 - 0.072 12.7 0.0 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase enzyme family ABC_tran PF00005.27 KKK45577.1 - 1.1e-31 110.1 0.0 1.9e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKK45577.1 - 4.2e-31 108.6 22.8 5.6e-31 108.2 22.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KKK45577.1 - 6.8e-07 28.9 0.2 6.7e-05 22.4 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK45577.1 - 0.00025 21.3 0.2 0.0018 18.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KKK45577.1 - 0.00028 21.3 0.1 0.0007 20.0 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 KKK45577.1 - 0.00034 20.4 0.3 0.0027 17.5 0.1 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Zeta_toxin PF06414.12 KKK45577.1 - 0.00097 18.5 0.1 0.0034 16.7 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.17 KKK45577.1 - 0.0089 16.1 0.2 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 KKK45577.1 - 0.0093 16.4 0.1 0.11 12.9 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KKK45577.1 - 0.011 16.2 0.1 0.026 15.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KKK45577.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KKK45577.1 - 0.097 12.4 0.1 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KKK45577.1 - 0.16 11.6 0.7 0.5 10.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KKK45577.1 - 0.17 11.6 0.1 0.42 10.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KKK45578.1 - 4.3e-35 121.2 0.1 8.2e-35 120.3 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KKK45578.1 - 2.7e-30 106.0 22.1 3.8e-30 105.5 22.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KKK45578.1 - 5.3e-07 29.3 0.8 0.0013 18.2 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 KKK45578.1 - 0.00035 20.4 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_21 PF13304.6 KKK45578.1 - 0.0008 19.3 1.2 0.011 15.6 0.3 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KKK45578.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KKK45578.1 - 0.0012 19.4 0.0 0.0029 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KKK45578.1 - 0.0024 18.1 0.2 0.0082 16.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KKK45578.1 - 0.0062 17.0 0.0 0.073 13.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KKK45578.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 KKK45578.1 - 0.027 14.5 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Roc PF08477.13 KKK45578.1 - 0.028 14.6 0.0 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KKK45578.1 - 0.031 14.0 0.3 0.069 12.9 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KKK45578.1 - 0.049 14.1 0.1 0.18 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KKK45578.1 - 0.081 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KKK45578.1 - 0.094 13.1 0.2 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 KKK45578.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 KKK45578.1 - 0.12 12.5 0.1 0.37 10.9 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Beta-lactamase PF00144.24 KKK45579.1 - 3e-61 207.5 0.0 3.9e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase PcfK PF14058.6 KKK45580.1 - 0.11 12.7 1.0 0.27 11.5 1.0 1.8 1 1 0 1 1 1 0 PcfK-like protein NYN PF01936.18 KKK45581.1 - 2.4e-27 96.2 0.3 2.9e-27 96.0 0.3 1.1 1 0 0 1 1 1 1 NYN domain DUF4268 PF14088.6 KKK45581.1 - 0.055 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) DUF169 PF02596.15 KKK45582.1 - 4.6e-31 108.4 0.0 5.3e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ArCR, COG2043 NosD PF05048.13 KKK45583.1 - 6.8e-37 127.0 41.8 1.9e-36 125.6 41.8 1.7 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK45583.1 - 5.8e-20 71.7 40.7 5.8e-20 71.7 40.7 2.5 1 1 1 2 2 2 2 Right handed beta helix region DsbC_N PF10411.9 KKK45583.1 - 0.031 13.7 0.0 9.8 5.7 0.0 2.6 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus MFS_1 PF07690.16 KKK45585.1 - 1.2e-19 70.4 27.6 2.3e-12 46.6 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 KKK45585.1 - 5.3 5.3 11.2 0.15 10.4 3.4 2.1 2 1 0 2 2 2 0 Transmembrane secretion effector MFS_1 PF07690.16 KKK45586.1 - 5.3e-11 42.0 1.5 6.2e-11 41.8 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK45586.1 - 0.0017 17.3 1.2 0.002 17.1 1.2 1.2 1 0 0 1 1 1 1 MFS_1 like family Molybdopterin PF00384.22 KKK45589.1 - 2.5e-17 63.0 0.0 2.9e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 KKK45589.1 - 3e-09 36.7 0.0 4.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Oxidored_FMN PF00724.20 KKK45590.1 - 8.9e-64 215.9 0.0 1.1e-63 215.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 KKK45590.1 - 8.6e-16 58.0 0.9 1.8e-15 56.9 0.9 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK45590.1 - 7.9e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KKK45590.1 - 8.2e-07 29.2 0.0 8.2e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KKK45590.1 - 6.2e-06 25.2 0.2 6.2e-06 25.2 0.2 2.7 2 1 1 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 KKK45590.1 - 1.1e-05 24.7 0.1 3e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KKK45590.1 - 0.00026 20.2 0.0 0.00047 19.3 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KKK45590.1 - 0.00048 20.6 0.8 0.00048 20.6 0.8 4.8 5 1 0 5 5 5 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK45590.1 - 0.0019 17.5 0.1 0.049 12.9 0.1 2.2 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 KKK45590.1 - 0.0027 17.1 2.2 0.0062 15.9 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KKK45590.1 - 0.0094 15.2 3.3 0.52 9.5 0.2 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK45590.1 - 0.016 14.8 5.9 0.049 13.2 0.1 2.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KKK45590.1 - 0.024 13.9 0.1 0.024 13.9 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Dus PF01207.17 KKK45590.1 - 0.029 13.5 0.0 0.086 11.9 0.0 1.7 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) NAD_binding_7 PF13241.6 KKK45590.1 - 0.073 13.5 1.0 5.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding K_oxygenase PF13434.6 KKK45590.1 - 0.1 11.7 0.1 4 6.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KKK45591.1 - 1.1e-05 24.9 0.0 1.1e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK45591.1 - 0.04 13.2 0.0 0.043 13.1 0.0 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 KKK45592.1 - 4.6e-53 180.3 0.0 5.5e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Vps55 PF04133.14 KKK45592.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 55 AMP-binding_C PF13193.6 KKK45592.1 - 0.048 14.6 0.0 0.091 13.8 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF3043 PF11241.8 KKK45593.1 - 0.2 11.6 0.4 0.35 10.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) rve PF00665.26 KKK45594.1 - 2.9e-06 27.5 0.0 5.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 KKK45594.1 - 0.00026 21.6 0.1 0.00055 20.5 0.1 1.6 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 KKK45594.1 - 0.0015 18.5 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_3 PF01381.22 KKK45594.1 - 0.0029 17.6 0.2 0.01 15.8 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix HTH_36 PF13730.6 KKK45594.1 - 0.0091 15.9 0.2 0.039 13.9 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 KKK45594.1 - 0.01 15.6 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 KKK45594.1 - 0.011 15.4 0.4 0.019 14.7 0.4 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 KKK45594.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SBP_bac_5 PF00496.22 KKK45595.1 - 3.4e-21 75.6 11.0 1.6e-15 57.0 3.1 2.4 2 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 KKK45596.1 - 1.3e-36 126.1 9.9 1.3e-36 126.1 9.9 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PARP_regulatory PF01358.18 KKK45596.1 - 0.052 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit Spore_YtfJ PF09579.10 KKK45596.1 - 0.076 13.2 0.4 0.24 11.6 0.4 1.9 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) BPD_transp_1 PF00528.22 KKK45597.1 - 1.6e-28 99.7 12.5 1.6e-28 99.7 12.5 2.2 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 KKK45598.1 - 1.3e-25 90.5 0.0 2.2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KKK45598.1 - 7.1e-19 68.1 0.1 1.4e-18 67.1 0.1 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region ResIII PF04851.15 KKK45598.1 - 0.0047 17.0 0.7 0.043 13.8 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA PF00004.29 KKK45598.1 - 0.14 12.6 0.0 10 6.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KKK45599.1 - 7.8e-35 120.4 0.0 1.2e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KKK45599.1 - 2.9e-15 56.5 0.2 5.1e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KKK45599.1 - 3.2e-09 37.0 0.8 7.9e-07 29.2 0.1 2.5 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK45599.1 - 2.1e-07 30.6 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KKK45599.1 - 1.1e-05 25.8 0.1 3.3e-05 24.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KKK45599.1 - 7.9e-05 23.1 0.1 0.0055 17.1 0.0 2.5 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK45599.1 - 0.00028 21.3 0.0 0.00052 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KKK45599.1 - 0.017 15.1 0.1 0.017 15.1 0.1 1.8 2 0 0 2 2 1 0 RsgA GTPase Sigma54_activat PF00158.26 KKK45599.1 - 0.017 14.8 0.2 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KKK45599.1 - 0.036 13.8 0.6 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 KKK45599.1 - 0.039 14.0 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 KKK45599.1 - 0.048 14.2 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK45599.1 - 0.069 12.7 0.0 0.32 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KKK45599.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 KKK45599.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 KKK45599.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 KKK45599.1 - 0.1 12.0 0.2 3 7.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein SbcCD_C PF13558.6 KKK45599.1 - 0.13 12.5 0.0 0.76 10.0 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KKK45599.1 - 0.13 12.0 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KKK45599.1 - 0.13 11.7 0.1 0.31 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PRK PF00485.18 KKK45599.1 - 0.15 11.8 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KKK45599.1 - 0.19 10.9 0.9 0.53 9.4 0.9 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.6 KKK45599.1 - 0.2 10.2 0.0 0.56 8.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain ZnuA PF01297.17 KKK45600.1 - 1 8.7 3.7 3 7.2 0.0 3.0 3 0 0 3 3 3 0 Zinc-uptake complex component A periplasmic CENP-H PF05837.12 KKK45600.1 - 8.8 6.8 7.5 3.7 8.0 0.0 3.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) LIM PF00412.22 KKK45601.1 - 0.0005 20.2 1.7 0.00058 20.0 1.7 1.1 1 0 0 1 1 1 1 LIM domain zinc_ribbon_2 PF13240.6 KKK45601.1 - 1.8 8.4 7.0 69 3.3 7.0 2.3 1 1 0 1 1 1 0 zinc-ribbon domain DUF2457 PF10446.9 KKK45601.1 - 3.3 6.8 21.1 3.1 6.9 21.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 KKK45601.1 - 4.9 7.2 8.0 4.8 7.2 8.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 KKK45601.1 - 8.3 4.6 10.0 7.8 4.7 10.0 1.0 1 0 0 1 1 1 0 CDC45-like protein GATase PF00117.28 KKK45602.1 - 8e-43 146.4 0.1 1.1e-42 146.0 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.14 KKK45602.1 - 2.4e-33 115.6 0.0 3.5e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.13 KKK45602.1 - 7.5e-10 38.9 0.2 3e-09 37.0 0.1 2.0 1 1 1 2 2 2 1 Peptidase C26 YfmQ PF10787.9 KKK45602.1 - 0.061 13.1 0.3 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group HATPase_c PF02518.26 KKK45605.1 - 1.2e-23 83.7 0.7 3.5e-23 82.2 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KKK45605.1 - 3.2e-16 59.5 0.5 7e-13 48.7 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KKK45605.1 - 6.6e-13 48.6 0.0 4.4e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 KKK45605.1 - 1.7e-10 40.7 2.5 2.6e-10 40.2 0.5 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 KKK45605.1 - 2.5e-09 37.3 0.0 5.5e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KKK45605.1 - 2.5e-08 33.8 0.0 5.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KKK45605.1 - 1.5e-05 25.2 0.0 9.3e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KKK45605.1 - 0.00068 19.7 0.0 0.0021 18.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain HNHc_6 PF16784.5 KKK45605.1 - 0.0021 17.7 3.8 0.32 10.5 0.9 2.9 3 1 0 3 3 3 2 Putative HNHc nuclease HATPase_c_3 PF13589.6 KKK45605.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pro_3_hydrox_C PF05373.11 KKK45605.1 - 0.078 13.1 0.3 0.59 10.3 0.0 2.4 2 1 1 3 3 3 0 L-proline 3-hydroxylase, C-terminal Siah-Interact_N PF09032.11 KKK45605.1 - 0.097 13.0 0.4 0.097 13.0 0.4 2.4 3 0 0 3 3 3 0 Siah interacting protein, N terminal Plk4_PB1 PF18190.1 KKK45605.1 - 0.15 12.2 1.5 4.4 7.5 0.1 2.8 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 DNA_ligase_A_N PF04675.14 KKK45605.1 - 0.17 12.2 3.1 0.099 13.0 1.0 1.7 2 0 0 2 2 2 0 DNA ligase N terminus DUF3800 PF12686.7 KKK45605.1 - 1.9 9.1 9.0 21 5.8 9.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) TQ PF18202.1 KKK45607.1 - 0.14 12.7 2.6 1.5 9.3 0.4 2.1 1 1 1 2 2 2 0 T-Q ester bond containing domain Fer4_7 PF12838.7 KKK45608.1 - 1.8e-17 63.6 32.4 3.7e-09 37.0 6.6 4.0 3 2 1 4 4 4 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45608.1 - 6.5e-17 60.6 47.7 2e-06 27.4 4.0 6.5 7 0 0 7 7 7 4 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45608.1 - 4.5e-11 43.5 33.3 0.0082 17.1 5.2 5.3 3 2 2 5 5 5 4 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK45608.1 - 7e-10 38.9 35.6 1.1e-06 28.6 7.5 3.8 2 2 2 4 4 4 4 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK45608.1 - 2.9e-09 36.9 37.3 0.00041 20.4 11.5 4.6 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45608.1 - 7.8e-09 35.5 42.6 1.4e-05 25.1 0.2 5.2 4 2 1 5 5 5 4 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45608.1 - 4.2e-06 27.1 28.8 0.036 14.5 0.0 4.0 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45608.1 - 6.8e-05 22.8 45.5 0.017 15.1 2.2 5.6 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_17 PF13534.6 KKK45608.1 - 0.0035 17.9 38.8 0.01 16.3 0.1 4.7 2 1 3 5 5 4 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45608.1 - 0.0035 17.4 43.0 0.14 12.3 0.7 5.5 5 0 0 5 5 5 4 4Fe-4S binding domain Fer4_4 PF12800.7 KKK45608.1 - 0.0037 17.7 52.8 0.023 15.2 3.3 5.3 6 1 0 6 6 5 4 4Fe-4S binding domain Fer4_22 PF17179.4 KKK45608.1 - 0.55 11.1 0.1 0.55 11.1 0.1 5.0 3 1 2 5 5 5 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK45608.1 - 4.8 8.4 57.7 0.11 13.4 3.8 5.4 6 0 0 6 6 6 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK45608.1 - 8.5 6.6 31.5 2 8.6 0.8 5.0 3 1 2 5 5 5 0 4Fe-4S dicluster domain PAS PF00989.25 KKK45609.1 - 2.2e-19 69.5 0.0 6.8e-15 55.1 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 KKK45609.1 - 6.8e-16 58.5 0.0 2.5e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold HATPase_c PF02518.26 KKK45609.1 - 2.5e-15 57.0 0.7 2.5e-15 57.0 0.7 3.1 2 2 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 KKK45609.1 - 3.2e-15 56.3 3.6 6.5e-11 42.4 0.1 3.5 3 1 0 3 3 3 2 PAS domain PAS_3 PF08447.12 KKK45609.1 - 1e-07 32.1 0.0 0.0001 22.5 0.0 4.2 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.7 KKK45609.1 - 1.2e-07 31.5 0.0 0.0097 15.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain HATPase_c_5 PF14501.6 KKK45609.1 - 0.00044 20.1 6.9 0.007 16.3 6.9 2.5 1 1 0 1 1 1 1 GHKL domain HisKA PF00512.25 KKK45609.1 - 0.00067 19.6 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 KKK45609.1 - 0.0013 18.9 0.0 0.29 11.3 0.0 2.9 2 1 0 2 2 2 1 PAS fold PAS_10 PF13596.6 KKK45609.1 - 0.0087 16.6 0.0 0.059 14.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain Maf PF02545.14 KKK45609.1 - 0.032 14.1 0.3 3.1 7.6 0.0 2.9 2 1 0 3 3 3 0 Maf-like protein H_kinase_N PF12282.8 KKK45609.1 - 0.079 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Signal transduction histidine kinase HATPase_c_2 PF13581.6 KKK45609.1 - 0.088 12.8 0.1 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain K_oxygenase PF13434.6 KKK45609.1 - 0.11 11.7 0.3 0.18 10.9 0.3 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Response_reg PF00072.24 KKK45610.1 - 3.3e-19 69.1 0.2 3.8e-19 68.9 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 KKK45610.1 - 0.052 13.9 0.0 0.06 13.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HTH_20 PF12840.7 KKK45612.1 - 3.1e-10 39.9 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 KKK45612.1 - 8.5e-10 38.3 0.6 8.5e-10 38.3 0.6 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KKK45612.1 - 3.1e-05 23.7 0.1 6.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KKK45612.1 - 3.4e-05 23.3 0.5 6.9e-05 22.3 0.5 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 KKK45612.1 - 3.6e-05 23.6 0.7 0.00012 21.9 0.7 1.9 1 0 0 1 1 1 1 HTH domain RepL PF05732.11 KKK45612.1 - 0.0021 17.5 0.4 0.0021 17.5 0.4 2.3 2 1 1 3 3 3 1 Firmicute plasmid replication protein (RepL) HxlR PF01638.17 KKK45612.1 - 0.0025 17.6 0.3 0.0079 16.0 0.2 2.0 2 0 0 2 2 2 1 HxlR-like helix-turn-helix MazG-like PF12643.7 KKK45612.1 - 0.0032 17.7 0.3 0.011 16.0 0.3 1.9 1 0 0 1 1 1 1 MazG-like family HTH_Crp_2 PF13545.6 KKK45612.1 - 0.004 17.1 1.2 0.01 15.8 0.3 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 KKK45612.1 - 0.02 14.8 0.1 0.067 13.1 0.1 1.9 1 0 0 1 1 1 0 MarR family Phage_rep_O PF04492.13 KKK45612.1 - 0.025 15.1 0.1 0.087 13.4 0.1 1.9 1 0 0 1 1 1 0 Bacteriophage replication protein O HTH_10 PF04967.12 KKK45612.1 - 0.026 14.3 0.8 0.056 13.3 0.3 1.8 2 0 0 2 2 2 0 HTH DNA binding domain YdaS_antitoxin PF15943.5 KKK45612.1 - 0.029 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 KKK45612.1 - 0.033 14.0 0.9 0.087 12.7 0.2 2.0 2 0 0 2 2 2 0 Homeodomain-like domain ATP-grasp_4 PF13535.6 KKK45612.1 - 0.057 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain Sigma70_r4 PF04545.16 KKK45612.1 - 0.071 12.7 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 KKK45612.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix KORA PF16509.5 KKK45612.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Osmo_CC PF08946.10 KKK45612.1 - 0.77 10.1 6.0 11 6.4 0.5 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil AAA PF00004.29 KKK45613.1 - 1.1e-95 317.1 0.0 2.5e-47 160.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK45613.1 - 2e-23 81.9 0.1 2.8e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KKK45613.1 - 4.7e-15 56.4 0.0 9.1e-07 29.4 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KKK45613.1 - 4.8e-14 52.4 0.1 2e-06 27.7 0.0 3.6 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KKK45613.1 - 1.6e-13 51.2 0.0 4e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KKK45613.1 - 1.9e-11 44.4 0.2 0.002 18.4 0.0 3.9 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.14 KKK45613.1 - 5.5e-11 42.6 0.3 0.00037 20.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 KKK45613.1 - 1.8e-10 40.4 0.1 8.7e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 KKK45613.1 - 2.5e-10 40.1 3.5 0.00042 19.6 0.0 3.4 3 1 0 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 KKK45613.1 - 5.7e-10 39.5 0.0 0.00017 21.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KKK45613.1 - 2.2e-09 37.5 0.0 0.0013 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KKK45613.1 - 1.3e-08 34.7 0.0 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 KKK45613.1 - 7.9e-08 32.7 0.0 0.0087 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KKK45613.1 - 8.4e-08 32.8 0.1 0.0087 16.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 KKK45613.1 - 6.1e-07 29.5 0.0 0.032 14.2 0.0 3.0 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KKK45613.1 - 7.8e-07 28.7 0.2 0.029 13.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KKK45613.1 - 4.2e-06 26.5 0.2 0.48 10.0 0.0 3.7 2 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KKK45613.1 - 6e-06 26.6 0.0 0.2 12.1 0.0 2.7 3 0 0 3 3 2 2 RNA helicase Sigma54_activat PF00158.26 KKK45613.1 - 1.2e-05 25.1 0.0 0.21 11.2 0.0 3.0 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 KKK45613.1 - 1.7e-05 24.8 0.0 0.42 10.5 0.0 3.5 3 0 0 3 3 3 2 NACHT domain PhoH PF02562.16 KKK45613.1 - 3.5e-05 23.3 0.0 0.34 10.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ATPase PF06745.13 KKK45613.1 - 4e-05 23.1 0.4 0.29 10.5 0.0 3.6 3 1 1 4 4 3 2 KaiC DUF815 PF05673.13 KKK45613.1 - 5.4e-05 22.5 0.0 0.32 10.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF815) ABC_tran PF00005.27 KKK45613.1 - 6.3e-05 23.5 0.0 0.33 11.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.11 KKK45613.1 - 6.4e-05 22.8 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KKK45613.1 - 7.5e-05 22.0 0.0 0.073 12.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KKK45613.1 - 0.00011 21.6 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KKK45613.1 - 0.00011 21.9 0.0 0.4 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KKK45613.1 - 0.00012 21.9 0.4 0.29 10.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 KKK45613.1 - 0.00015 21.1 0.0 0.54 9.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 KKK45613.1 - 0.00016 21.3 0.0 0.64 9.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 KKK45613.1 - 0.00065 19.5 0.0 0.63 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KKK45613.1 - 0.00092 19.1 0.0 0.98 9.2 0.0 3.0 2 0 0 2 2 2 1 Bacterial dnaA protein ATPase_2 PF01637.18 KKK45613.1 - 0.0014 18.6 0.0 5.8 6.7 0.0 4.0 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KKK45613.1 - 0.0017 18.5 0.0 0.84 9.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 KKK45613.1 - 0.0019 18.6 0.5 3.9 7.8 0.0 3.0 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.22 KKK45613.1 - 0.0046 16.2 0.0 2.3 7.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 KKK45613.1 - 0.0048 16.7 0.0 0.37 10.5 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KKK45613.1 - 0.0068 16.8 0.0 2.1 8.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain DAP3 PF10236.9 KKK45613.1 - 0.0074 15.5 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 KKK45613.1 - 0.0093 15.4 0.0 6.3 6.2 0.0 3.4 3 0 0 3 3 3 0 Bacterial TniB protein Cytidylate_kin PF02224.18 KKK45613.1 - 0.012 15.4 0.0 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 KKK45613.1 - 0.013 15.4 0.0 1.5 8.7 0.0 2.7 2 1 0 2 2 2 0 Rad17 P-loop domain Cytidylate_kin2 PF13189.6 KKK45613.1 - 0.015 15.4 1.2 2.9 8.0 0.0 3.3 4 0 0 4 4 3 0 Cytidylate kinase-like family AFG1_ATPase PF03969.16 KKK45613.1 - 0.022 13.7 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.15 KKK45613.1 - 0.023 14.6 0.3 22 4.9 0.0 4.2 4 1 0 4 4 4 0 NTPase Zot PF05707.12 KKK45613.1 - 0.026 14.1 0.0 0.22 11.1 0.0 2.5 3 0 0 3 3 2 0 Zonular occludens toxin (Zot) ResIII PF04851.15 KKK45613.1 - 0.027 14.5 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CPT PF07931.12 KKK45613.1 - 0.029 14.2 0.0 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Hydin_ADK PF17213.3 KKK45613.1 - 0.073 13.3 1.8 5.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain IPT PF01745.16 KKK45613.1 - 0.083 12.3 0.0 10 5.4 0.0 3.0 3 0 0 3 3 3 0 Isopentenyl transferase SKI PF01202.22 KKK45613.1 - 0.091 12.9 0.0 16 5.6 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase AAA_29 PF13555.6 KKK45613.1 - 0.1 12.3 0.0 19 5.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain PAS_2 PF08446.11 KKK45613.1 - 0.13 12.9 0.0 4.6 8.0 0.0 2.5 2 0 0 2 2 2 0 PAS fold PduV-EutP PF10662.9 KKK45613.1 - 0.17 11.6 0.0 6.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation LRR_4 PF12799.7 KKK45617.1 - 1e-13 51.2 27.0 6.8e-07 29.5 4.0 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK45617.1 - 3.8e-09 36.2 38.4 6.3e-06 25.9 8.3 3.1 1 1 3 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KKK45617.1 - 4.1e-07 29.7 8.0 1.6e-06 27.7 6.5 1.9 1 1 1 2 2 2 1 Leucine-rich repeat UB2H PF14814.6 KKK45617.1 - 0.066 13.2 1.0 9.4 6.3 0.0 3.4 1 1 3 4 4 4 0 Bifunctional transglycosylase second domain Arm_3 PF16186.5 KKK45617.1 - 0.072 12.7 0.7 7 6.3 0.3 3.1 3 1 0 3 3 3 0 Atypical Arm repeat LRR_6 PF13516.6 KKK45617.1 - 0.26 11.4 8.5 23 5.4 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Octopine_DH PF02317.17 KKK45618.1 - 2.5e-37 128.3 0.0 3.8e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 KKK45618.1 - 1.3e-13 51.3 0.1 2.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KKK45618.1 - 2e-09 37.3 0.2 3.3e-09 36.6 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KKK45618.1 - 3.5e-07 30.7 0.1 7.2e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KKK45618.1 - 2.4e-06 27.8 0.0 3.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KKK45618.1 - 5.4e-06 26.1 0.1 9.9e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 KKK45618.1 - 0.00072 19.6 0.3 0.0077 16.3 0.1 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KKK45618.1 - 0.0013 18.3 0.1 0.025 14.2 0.1 2.1 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 KKK45618.1 - 0.0048 16.8 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KKK45618.1 - 0.062 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 KKK45618.1 - 0.079 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KKK45618.1 - 0.16 12.4 0.1 0.64 10.5 0.1 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Propep_M14 PF02244.16 KKK45618.1 - 0.18 12.2 0.6 18 5.8 0.0 3.7 4 0 0 4 4 4 0 Carboxypeptidase activation peptide Tautomerase PF01361.21 KKK45619.1 - 1.3e-07 31.4 0.0 1.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 KKK45619.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Tautomerase enzyme Acetyltransf_1 PF00583.25 KKK45620.1 - 1.6e-13 50.9 0.0 1.9e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK45620.1 - 2.7e-13 49.9 0.0 4e-13 49.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK45620.1 - 5.4e-11 42.8 0.0 7.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK45620.1 - 8.1e-08 32.4 0.0 1.4e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK45620.1 - 1.2e-07 31.6 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KKK45620.1 - 0.014 14.9 0.0 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KKK45620.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase GNAT_acetyltran PF12746.7 KKK45620.1 - 0.027 14.0 0.0 0.053 13.1 0.0 1.4 2 0 0 2 2 2 0 GNAT acetyltransferase Acetyltransf_6 PF13480.7 KKK45620.1 - 0.03 14.5 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK45620.1 - 0.035 14.2 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase EamA PF00892.20 KKK45621.1 - 1.6e-30 106.1 50.6 2.9e-16 59.9 19.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KKK45621.1 - 0.00053 19.4 25.9 0.0042 16.5 6.1 3.1 2 1 1 3 3 3 2 Triose-phosphate Transporter family PUNUT PF16913.5 KKK45621.1 - 0.078 12.2 25.0 0.28 10.4 10.5 2.8 1 1 2 3 3 3 0 Purine nucleobase transmembrane transport Thiolase_N PF00108.23 KKK45622.1 - 1.3e-12 47.7 4.0 3.1e-11 43.1 0.7 3.0 1 1 1 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KKK45622.1 - 1.3e-11 44.2 1.3 5.9e-11 42.1 0.3 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KKK45622.1 - 0.0014 18.5 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KKK45622.1 - 0.0023 17.6 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KKK45622.1 - 0.028 14.4 0.1 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain UPF0014 PF03649.13 KKK45623.1 - 0.03 13.7 12.1 0.12 11.7 0.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0014) Thioredoxin_6 PF13848.6 KKK45623.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DctQ PF04290.12 KKK45623.1 - 0.073 13.0 8.0 0.62 10.0 0.1 3.6 3 2 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ost5 PF05251.12 KKK45623.1 - 0.073 13.3 0.1 0.073 13.3 0.1 3.4 3 1 0 3 3 3 0 Oligosaccharyltransferase subunit 5 YtpI PF14007.6 KKK45623.1 - 0.075 13.2 0.1 0.075 13.2 0.1 3.9 4 1 0 4 4 4 0 YtpI-like protein CD34_antigen PF06365.12 KKK45623.1 - 0.13 11.8 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF4519 PF15012.6 KKK45623.1 - 0.3 11.3 0.1 0.3 11.3 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) DUF4396 PF14342.6 KKK45623.1 - 0.57 10.5 6.2 3.3 8.1 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4396) NnrU PF07298.11 KKK45623.1 - 4.5 6.7 9.7 0.92 9.0 0.3 3.2 2 2 0 3 3 3 0 NnrU protein Phage_holin_3_6 PF07332.11 KKK45623.1 - 8.8 6.4 7.2 12 6.0 0.0 3.2 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III RseC_MucC PF04246.12 KKK45623.1 - 9.7 6.2 9.1 5.7 6.9 0.5 3.0 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC SLATT_4 PF18186.1 KKK45624.1 - 4.6e-05 23.1 3.0 6.2e-05 22.7 3.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 4 Ribosomal_S8 PF00410.19 KKK45624.1 - 0.078 12.9 1.7 0.13 12.2 1.7 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 LexA_DNA_bind PF01726.16 KKK45624.1 - 0.11 12.3 0.0 6.3 6.6 0.0 2.5 2 0 0 2 2 2 0 LexA DNA binding domain CCDC-167 PF15188.6 KKK45624.1 - 0.85 10.0 5.6 10 6.6 5.6 2.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 OrfB_Zn_ribbon PF07282.11 KKK45625.1 - 0.034 14.1 0.3 0.044 13.7 0.3 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C3HC4_3 PF13920.6 KKK45625.1 - 0.035 14.0 0.3 0.042 13.7 0.3 1.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PK PF00224.21 KKK45628.1 - 2.8e-112 375.1 4.5 3.8e-112 374.6 4.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KKK45628.1 - 7.4e-20 71.3 0.0 2e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KKK45628.1 - 0.00057 19.1 0.2 0.0031 16.7 0.0 2.1 3 0 0 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family RibD_C PF01872.17 KKK45628.1 - 0.041 13.7 0.0 0.087 12.6 0.0 1.5 1 1 0 1 1 1 0 RibD C-terminal domain IMPDH PF00478.25 KKK45628.1 - 0.05 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ATP-grasp_6 PF18419.1 KKK45628.1 - 0.25 11.0 2.5 0.56 9.9 0.1 2.5 2 0 0 2 2 2 0 ATP-grasp-like domain Sdh_cyt PF01127.22 KKK45629.1 - 0.76 9.8 9.1 1.4 8.9 8.8 1.8 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Rad51 PF08423.11 KKK45633.1 - 6.3e-92 307.4 0.0 8.4e-92 307.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KKK45633.1 - 7.2e-14 51.9 0.1 1.1e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KKK45633.1 - 9e-07 28.5 0.3 9e-07 28.5 0.3 2.1 2 0 0 2 2 2 1 KaiC HHH_5 PF14520.6 KKK45633.1 - 9.2e-07 29.4 0.3 2.3e-06 28.1 0.3 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 KKK45633.1 - 0.00013 21.7 0.0 0.00032 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain BAF PF02961.14 KKK45633.1 - 0.14 12.6 0.2 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Barrier to autointegration factor FYDLN_acid PF09538.10 KKK45633.1 - 0.19 12.4 1.3 0.31 11.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TcpA PF05946.12 KKK45634.1 - 5.2e-05 23.4 1.4 4.5 7.4 0.0 5.8 7 0 0 7 7 7 2 Toxin-coregulated pilus subunit TcpA NOD2_WH PF17779.1 KKK45634.1 - 0.0014 18.9 0.0 1.2e+02 3.1 0.0 6.2 8 0 0 8 8 8 0 NOD2 winged helix domain ATP-grasp_5 PF13549.6 KKK45635.1 - 1.6e-71 240.3 0.2 1.8e-71 240.1 0.2 1.0 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 KKK45635.1 - 0.00062 19.4 0.1 0.0024 17.5 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain Fer4_NifH PF00142.18 KKK45635.1 - 0.13 11.7 3.8 0.039 13.4 1.0 1.5 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family E1-E2_ATPase PF00122.20 KKK45636.1 - 3.3e-48 163.6 0.5 3.3e-48 163.6 0.5 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KKK45636.1 - 1.4e-29 103.1 9.1 1.4e-29 103.1 9.1 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KKK45636.1 - 6.2e-19 67.5 0.0 6.2e-19 67.5 0.0 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KKK45636.1 - 1.3e-17 64.8 3.7 1.6e-16 61.2 3.7 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KKK45636.1 - 4.5e-16 58.7 0.0 9.9e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 KKK45636.1 - 0.0021 18.5 0.1 0.0047 17.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK45636.1 - 0.022 14.5 4.0 0.28 10.9 0.4 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase ORMDL PF04061.14 KKK45638.1 - 0.0025 17.6 0.2 0.0025 17.6 0.2 2.1 2 1 0 2 2 2 1 ORMDL family RecR PF02132.15 KKK45639.1 - 0.0012 18.3 1.8 0.002 17.6 1.8 1.3 1 0 0 1 1 1 1 RecR protein zinc_ribbon_15 PF17032.5 KKK45639.1 - 0.03 15.1 0.2 0.041 14.6 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK45639.1 - 0.098 12.1 3.0 0.17 11.4 3.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.8 KKK45639.1 - 0.1 12.5 0.4 0.17 11.8 0.4 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 KKK45639.1 - 0.72 9.7 4.7 8.6 6.2 4.7 2.3 1 1 0 1 1 1 0 zinc-ribbon domain ParD_antitoxin PF03693.14 KKK45640.1 - 0.00013 22.3 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH PCI PF01399.27 KKK45640.1 - 0.011 16.3 2.0 0.011 16.3 2.0 2.2 2 1 0 2 2 2 0 PCI domain T4_Gp59_N PF08993.10 KKK45640.1 - 0.42 11.1 6.6 1.3 9.5 0.3 2.5 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase G10 PF01125.17 KKK45640.1 - 0.72 9.6 5.2 0.45 10.3 0.8 2.4 2 1 0 2 2 2 0 G10 protein zf-Di19 PF05605.12 KKK45641.1 - 0.0013 18.9 5.7 2.2 8.6 0.7 3.4 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding RNF220 PF15926.5 KKK45641.1 - 0.0083 15.8 8.7 0.031 13.9 2.7 2.4 1 1 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 DUF2750 PF11042.8 KKK45641.1 - 0.054 13.6 0.1 0.098 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) zf-ribbon_3 PF13248.6 KKK45641.1 - 0.15 11.5 6.7 2.2 7.8 0.0 3.2 4 0 0 4 4 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 KKK45641.1 - 0.19 11.6 6.1 1.7 8.6 0.3 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK45641.1 - 0.56 10.1 6.9 4.3 7.3 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 TF_Zn_Ribbon PF08271.12 KKK45641.1 - 0.88 9.1 5.9 6.8 6.3 0.1 3.6 3 0 0 3 3 3 0 TFIIB zinc-binding DUF2946 PF11162.8 KKK45641.1 - 0.96 10.1 2.5 28 5.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) zf-C2H2_4 PF13894.6 KKK45641.1 - 1.1 10.2 8.7 13 6.9 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KKK45641.1 - 1.3 9.1 8.2 3.7 7.7 0.3 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KKK45641.1 - 1.5 9.4 4.8 38 4.9 0.8 3.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-UDP PF14569.6 KKK45641.1 - 2.6 8.3 8.0 0.71 10.0 1.9 2.8 3 0 0 3 3 3 0 Zinc-binding RING-finger zf-C2HC_2 PF13913.6 KKK45641.1 - 3.6 7.6 13.5 6.5 6.8 0.2 3.7 3 1 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KKK45641.1 - 3.9 7.6 8.5 4.8 7.3 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Cys_rich_CPXG PF14255.6 KKK45641.1 - 5.2 7.0 7.7 12 5.8 0.3 3.4 3 0 0 3 3 3 0 Cysteine-rich CPXCG Zn-C2H2_12 PF18112.1 KKK45641.1 - 8.1 7.0 7.1 14 6.3 0.2 3.2 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain JAB PF01398.21 KKK45642.1 - 1.1e-11 44.8 0.0 2.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SNAP PF14938.6 KKK45642.1 - 0.00017 21.1 1.0 0.0031 17.0 0.1 2.2 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP Prok-JAB PF14464.6 KKK45642.1 - 0.00029 20.6 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TPR_8 PF13181.6 KKK45642.1 - 0.079 13.2 4.5 3 8.3 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4385 PF14328.6 KKK45642.1 - 0.2 11.7 1.7 11 6.1 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4385) TPP_enzyme_C PF02775.21 KKK45643.1 - 3e-20 72.6 0.0 4.5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KKK45644.1 - 6.8e-10 38.8 0.0 7.5e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CoA_transf_3 PF02515.17 KKK45645.1 - 4.5e-92 309.0 0.0 5e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III 3HCDH_N PF02737.18 KKK45648.1 - 1.5e-44 152.1 3.8 1.8e-44 151.7 3.8 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK45648.1 - 4.2e-29 101.0 0.0 8.2e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain PMBR PF09373.10 KKK45648.1 - 0.0022 18.0 1.2 0.0095 16.1 0.2 2.3 2 0 0 2 2 2 1 Pseudomurein-binding repeat Phage_XkdX PF09693.10 KKK45648.1 - 0.042 13.9 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Csc2 PF18320.1 KKK45648.1 - 0.66 8.9 4.5 1.2 8.0 0.4 2.2 1 1 1 2 2 2 0 Csc2 Crispr zf-B_box PF00643.24 KKK45649.1 - 0.0053 16.9 20.7 0.12 12.6 3.1 2.4 1 1 1 2 2 2 2 B-box zinc finger Siva PF05458.12 KKK45649.1 - 0.043 13.5 13.2 0.049 13.3 13.2 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF326 PF03860.16 KKK45649.1 - 0.052 13.5 9.1 0.052 13.5 9.1 2.6 3 1 0 3 3 3 0 Domain of Unknown Function (DUF326) XPA_N PF01286.18 KKK45649.1 - 0.11 12.5 3.9 0.11 12.5 3.9 3.7 2 1 2 4 4 4 0 XPA protein N-terminal FYVE PF01363.21 KKK45649.1 - 0.21 11.7 18.0 0.16 12.2 3.7 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_5 PF14634.6 KKK45649.1 - 0.32 11.0 20.5 7.3 6.6 10.0 2.6 1 1 1 2 2 2 0 zinc-RING finger domain FYVE_2 PF02318.16 KKK45649.1 - 1.8 8.8 16.2 4.1 7.6 16.2 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 KKK45649.1 - 2.2 8.4 22.3 33 4.6 22.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-AN1 PF01428.16 KKK45649.1 - 3.2 8.0 23.3 3.8 7.8 6.7 2.5 1 1 2 3 3 3 0 AN1-like Zinc finger DUF123 PF01986.16 KKK45650.1 - 1.2e-28 99.4 0.0 1.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF123 GIY-YIG PF01541.24 KKK45650.1 - 0.11 12.8 1.4 0.17 12.2 1.1 1.6 1 1 0 1 1 1 0 GIY-YIG catalytic domain adh_short_C2 PF13561.6 KKK45651.1 - 1.5e-37 129.4 1.8 2.2e-37 128.9 1.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK45651.1 - 4.8e-37 127.3 2.7 8.2e-37 126.6 2.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK45651.1 - 9.8e-16 58.2 0.9 2e-15 57.2 0.8 1.5 1 1 0 1 1 1 1 KR domain Romo1 PF10247.9 KKK45652.1 - 0.021 15.1 3.1 3.2 8.2 0.0 2.4 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.6 KKK45652.1 - 0.16 11.7 2.7 0.38 10.5 0.4 2.2 3 0 0 3 3 3 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KKK45652.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.4 3 0 0 3 3 3 0 Glycine zipper UPF0154 PF03672.13 KKK45652.1 - 1.1 9.3 0.1 1.1 9.3 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Rick_17kDa_Anti PF05433.15 KKK45652.1 - 2.8 7.9 9.3 0.39 10.6 0.9 2.6 3 0 0 3 3 3 0 Glycine zipper 2TM domain Robl_LC7 PF03259.17 KKK45653.1 - 1.4e-10 40.8 0.0 1.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain GatB_Yqey PF02637.18 KKK45654.1 - 2.3e-36 124.9 0.8 4.2e-36 124.1 0.8 1.5 1 0 0 1 1 1 1 GatB domain GatB_N PF02934.15 KKK45654.1 - 3.7e-29 102.0 0.3 6.2e-29 101.2 0.3 1.4 1 0 0 1 1 1 1 GatB/GatE catalytic domain MotY_N PF18393.1 KKK45654.1 - 0.066 13.3 0.1 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 MotY N-terminal domain DUF496 PF04363.12 KKK45654.1 - 0.33 11.0 8.5 0.13 12.3 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF496) RVT_1 PF00078.27 KKK45658.1 - 1.7e-35 122.5 0.0 3e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_N PF13655.6 KKK45658.1 - 4.3e-22 78.2 0.1 4.3e-22 78.2 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of reverse transcriptase GIIM PF08388.11 KKK45658.1 - 3.5e-21 75.0 10.6 3.5e-21 75.0 10.6 2.1 2 0 0 2 2 2 1 Group II intron, maturase-specific domain U5_2-snRNA_bdg PF10597.9 KKK45658.1 - 0.004 17.2 0.1 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 Intron_maturas2 PF01348.21 KKK45658.1 - 0.2 11.6 3.1 0.25 11.3 1.6 2.0 1 1 1 2 2 2 0 Type II intron maturase NMO PF03060.15 KKK45662.1 - 5.5e-43 147.6 0.0 1.3e-42 146.4 0.0 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK45662.1 - 2.9e-11 43.0 4.6 4.4e-09 35.8 0.4 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KKK45662.1 - 5.7e-08 32.2 0.2 1.8e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KKK45662.1 - 0.00052 19.5 1.0 0.00067 19.2 0.2 1.5 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF1729 PF08354.10 KKK45662.1 - 0.0035 16.3 0.1 0.013 14.4 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1729) ThiG PF05690.14 KKK45662.1 - 0.038 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KKK45662.1 - 0.06 12.6 0.3 0.096 11.9 0.3 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DHDPS PF00701.22 KKK45662.1 - 0.12 11.1 0.6 0.34 9.6 0.6 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate synthetase family HycI PF01750.18 KKK45663.1 - 1.8e-13 50.4 0.1 4e-11 42.8 0.0 2.6 1 1 2 3 3 3 2 Hydrogenase maturation protease PAS_9 PF13426.7 KKK45664.1 - 5e-49 164.9 15.8 4.9e-16 58.9 0.1 6.2 6 0 0 6 6 6 5 PAS domain MEDS PF14417.6 KKK45664.1 - 1.4e-47 161.5 0.0 3.6e-47 160.2 0.0 1.8 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain PAS PF00989.25 KKK45664.1 - 5.1e-45 152.1 0.9 6.3e-14 51.9 0.0 5.8 5 0 0 5 5 5 5 PAS fold PAS_4 PF08448.10 KKK45664.1 - 1.7e-41 140.9 0.0 6.9e-12 45.6 0.0 6.2 6 0 0 6 6 6 5 PAS fold PAS_8 PF13188.7 KKK45664.1 - 5e-36 122.1 0.1 4.3e-09 36.2 0.0 6.0 5 0 0 5 5 5 5 PAS domain PAS_3 PF08447.12 KKK45664.1 - 7.7e-30 103.0 0.8 5.5e-08 33.0 0.0 5.8 6 0 0 6 6 5 4 PAS fold HATPase_c PF02518.26 KKK45664.1 - 2.3e-23 82.8 0.3 7.5e-23 81.2 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK45664.1 - 1.6e-11 44.0 0.3 6.9e-11 42.0 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 KKK45664.1 - 1.6e-05 25.0 6.8 1.3 9.2 0.0 6.6 7 3 0 7 7 7 1 PAS fold PAS_12 PF18095.1 KKK45664.1 - 5.6e-05 22.8 1.7 1.6 8.3 0.1 4.7 5 0 0 5 5 5 1 UPF0242 C-terminal PAS-like domain MEKHLA PF08670.11 KKK45664.1 - 0.00034 20.5 0.0 0.004 17.0 0.0 2.4 2 0 0 2 2 2 1 MEKHLA domain HATPase_c_2 PF13581.6 KKK45664.1 - 0.0021 18.0 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain H_kinase_N PF12282.8 KKK45664.1 - 0.0036 17.3 0.0 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 Signal transduction histidine kinase HPS6 PF15702.5 KKK45664.1 - 0.029 12.4 0.1 0.052 11.6 0.1 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein HATPase_c_3 PF13589.6 KKK45664.1 - 0.085 12.7 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DMPK_coil PF08826.10 KKK45664.1 - 1.5 9.0 6.8 6.2 7.0 0.2 3.9 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF3800 PF12686.7 KKK45664.1 - 1.8 9.2 5.3 15 6.3 0.1 4.1 2 2 0 3 3 3 0 Protein of unknown function (DUF3800) tRNA_int_endo PF01974.17 KKK45665.1 - 1.7e-17 63.3 0.1 2.6e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KKK45665.1 - 2.6e-05 23.8 0.1 5.1e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain T2SSE PF00437.20 KKK45667.1 - 1.2e-05 24.5 0.1 1.9e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 KKK45667.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KKK45667.1 - 0.0024 18.4 0.0 0.089 13.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KKK45667.1 - 0.0048 16.2 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KKK45667.1 - 0.0065 16.7 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KKK45667.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 KKK45667.1 - 0.042 13.2 0.0 0.099 12.0 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 KKK45667.1 - 0.051 13.8 0.0 0.096 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK45667.1 - 0.056 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 KKK45667.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLP1_P PF16575.5 KKK45667.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_17 PF13207.6 KKK45667.1 - 0.11 12.9 0.1 1.4 9.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KKK45667.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KKK45667.1 - 0.13 12.8 0.0 0.67 10.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ArsA_ATPase PF02374.15 KKK45667.1 - 0.13 11.4 0.4 0.35 10.0 0.1 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase SRP54 PF00448.22 KKK45667.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 KKK45667.1 - 0.2 12.0 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Zn-ribbon_8 PF09723.10 KKK45671.1 - 0.016 15.3 1.1 3.3 7.9 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C4_Topoisom PF01396.19 KKK45671.1 - 0.017 14.9 1.3 0.13 12.0 0.1 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger YhfH PF14149.6 KKK45671.1 - 0.027 14.4 0.1 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 YhfH-like protein zf-ISL3 PF14690.6 KKK45671.1 - 0.033 14.9 0.6 0.08 13.6 0.6 1.7 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 RNA_POL_M_15KD PF02150.16 KKK45671.1 - 0.055 13.3 1.6 8.3 6.4 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.6 KKK45671.1 - 0.069 13.5 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-AN1 PF01428.16 KKK45671.1 - 0.14 12.3 0.5 0.14 12.3 0.5 1.9 2 0 0 2 2 2 0 AN1-like Zinc finger zf-ribbon_3 PF13248.6 KKK45671.1 - 0.15 11.5 2.3 0.53 9.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 KKK45671.1 - 0.18 11.4 2.6 7.7 6.2 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DDE_Tnp_ISL3 PF01610.17 KKK45672.1 - 0.0033 17.2 0.3 0.0066 16.2 0.3 1.5 1 0 0 1 1 1 1 Transposase Syntaxin-6_N PF09177.11 KKK45672.1 - 0.055 14.0 0.7 1.3 9.6 0.1 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal His_Phos_1 PF00300.22 KKK45673.1 - 2.5e-33 115.4 0.0 1.1e-25 90.5 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Glyco_hydro_2_N PF02837.18 KKK45674.1 - 1e-19 71.0 2.6 4.3e-19 69.0 2.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KKK45674.1 - 1e-16 60.9 0.0 3.9e-15 55.7 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KKK45674.1 - 6.8e-07 29.9 0.0 1.3e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KKK45674.1 - 0.0075 16.8 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Nitroreductase PF00881.24 KKK45676.1 - 6.7e-07 29.5 0.0 8.2e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK45676.1 - 0.015 14.8 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Putative TM nitroreductase MaoC_dehydratas PF01575.19 KKK45679.1 - 2.5e-27 94.9 0.0 4e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KKK45679.1 - 2.7e-07 30.8 0.0 2.5e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Lactamase_B PF00753.27 KKK45680.1 - 1.4e-10 41.5 0.4 2.6e-09 37.4 0.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily NMO PF03060.15 KKK45682.1 - 6.7e-45 153.9 0.0 1.4e-44 152.9 0.0 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KKK45682.1 - 1.9e-08 33.7 0.1 1e-07 31.4 0.1 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KKK45682.1 - 6.2e-08 32.0 0.7 5.7e-05 22.3 0.3 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 KKK45682.1 - 0.0025 17.1 0.2 0.0047 16.2 0.2 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KKK45682.1 - 0.012 14.7 0.8 0.03 13.4 0.8 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 KKK45682.1 - 0.023 14.2 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF1729 PF08354.10 KKK45682.1 - 0.038 12.9 0.1 0.17 10.8 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1729) CCG PF02754.16 KKK45683.1 - 8.2e-12 45.2 0.8 6.7e-05 23.0 0.0 2.6 2 1 0 2 2 2 2 Cysteine-rich domain Metallophos PF00149.28 KKK45684.1 - 9.6e-11 42.6 2.9 1.1e-09 39.1 2.9 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK45684.1 - 3.6e-06 27.3 0.0 0.0084 16.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_36C PF16874.5 KKK45684.1 - 0.0052 17.2 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain Abhydrolase_1 PF00561.20 KKK45685.1 - 3.6e-06 26.8 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 KKK45685.1 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cys_Met_Meta_PP PF01053.20 KKK45686.1 - 1.5e-72 244.3 0.0 8.9e-72 241.7 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KKK45686.1 - 0.011 14.7 0.1 0.019 13.9 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Nitroreductase PF00881.24 KKK45688.1 - 5.7e-24 85.1 0.0 7e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 KKK45688.1 - 7.8e-09 35.4 0.0 0.0019 17.8 0.2 2.6 1 1 0 2 2 2 2 Putative TM nitroreductase Fer4_10 PF13237.6 KKK45688.1 - 1.7e-08 34.4 9.5 3.3e-08 33.5 9.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45688.1 - 2.3e-08 34.5 5.5 0.0018 18.8 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45688.1 - 3.2e-08 33.6 11.2 5.4e-08 32.9 11.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45688.1 - 1.3e-07 31.4 10.1 0.0004 20.3 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 KKK45688.1 - 1.3e-07 31.1 12.8 0.0012 18.6 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45688.1 - 5e-07 30.6 4.2 0.0037 18.2 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KKK45688.1 - 2.7e-06 27.1 12.5 0.0011 18.9 3.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK45688.1 - 3.3e-06 27.1 8.8 0.0029 17.7 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45688.1 - 3.2e-05 24.3 5.3 0.068 13.6 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK45688.1 - 0.00096 19.7 11.6 0.0034 17.9 1.2 2.4 1 1 1 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KKK45688.1 - 0.0013 18.9 10.1 0.0042 17.3 9.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK45688.1 - 0.0025 18.6 16.7 0.13 13.3 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain GAGBD PF16828.5 KKK45688.1 - 0.017 15.2 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 GAG-binding domain on surface antigen Fer4_4 PF12800.7 KKK45688.1 - 0.02 15.4 14.8 0.62 10.7 4.2 2.3 1 1 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK45688.1 - 0.084 13.4 13.6 0.77 10.3 2.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK45688.1 - 0.3 11.9 9.2 1.4 9.7 1.1 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain ETF_QO PF05187.13 KKK45688.1 - 1.6 8.9 4.5 3 8.0 4.5 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S zf-C3HC4_3 PF13920.6 KKK45689.1 - 0.00054 19.8 8.0 0.0013 18.6 8.0 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 KKK45689.1 - 0.0067 16.7 6.5 0.0069 16.7 3.2 2.3 2 0 0 2 2 2 1 C1 domain TPR_12 PF13424.6 KKK45689.1 - 0.37 11.1 8.1 1.1 9.6 0.3 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 KKK45689.1 - 0.81 9.5 9.9 0.73 9.7 6.6 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KKK45689.1 - 0.99 9.5 7.9 12 6.0 8.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.6 KKK45689.1 - 1.2 9.1 8.9 3.2 7.8 8.7 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KKK45689.1 - 1.4 9.3 7.6 2.5 8.5 7.6 1.4 1 0 0 1 1 1 0 Ring finger domain DUF2203 PF09969.9 KKK45689.1 - 2.4 8.9 5.0 2.9 8.6 1.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3267 PF11667.8 KKK45691.1 - 0.00019 21.7 4.4 0.00019 21.7 4.4 2.7 1 1 2 3 3 3 1 Putative zincin peptidase Peptidase_M50 PF02163.22 KKK45691.1 - 0.0092 15.3 0.8 0.017 14.4 0.8 1.4 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M50B PF13398.6 KKK45691.1 - 0.71 9.5 15.8 12 5.5 15.1 2.8 1 1 0 1 1 1 0 Peptidase M50B-like RseC_MucC PF04246.12 KKK45692.1 - 0.24 11.4 0.4 0.35 10.8 0.4 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF4181 PF13789.6 KKK45692.1 - 0.97 9.7 7.7 2 8.7 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) FeoB_associated PF12669.7 KKK45692.1 - 1.4 9.3 5.8 0.28 11.6 1.0 1.9 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF2208 PF09973.9 KKK45692.1 - 8.7 5.9 11.1 27 4.3 11.1 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) AAA_22 PF13401.6 KKK45693.1 - 9.9e-07 29.1 0.0 2e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KKK45693.1 - 4.8e-05 22.8 0.0 0.00011 21.6 0.0 1.6 2 0 0 2 2 2 1 KaiC Rad51 PF08423.11 KKK45693.1 - 0.00017 20.9 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Rad51 Sigma54_activat PF00158.26 KKK45693.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KKK45693.1 - 0.0029 18.0 0.0 0.004 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 KKK45693.1 - 0.0039 16.7 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_11 PF13086.6 KKK45693.1 - 0.0061 16.4 0.0 0.0098 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KKK45693.1 - 0.012 15.8 0.1 0.044 13.9 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 KKK45693.1 - 0.013 16.0 0.0 0.021 15.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KKK45693.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK45693.1 - 0.017 14.7 0.0 0.062 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KKK45693.1 - 0.017 15.0 0.2 0.025 14.5 0.2 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KKK45693.1 - 0.034 14.6 0.0 0.12 12.8 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KKK45693.1 - 0.041 13.1 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KKK45693.1 - 0.056 13.2 0.0 0.55 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KKK45693.1 - 0.06 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KKK45693.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 KKK45693.1 - 0.081 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain PRK PF00485.18 KKK45693.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RsgA_GTPase PF03193.16 KKK45693.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 KKK45693.1 - 0.093 12.8 0.1 0.64 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KKK45693.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein His_Me_b4a2 PF18275.1 KKK45694.1 - 0.14 12.2 0.1 5 7.3 0.1 2.2 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain PIN PF01850.21 KKK45695.1 - 3.6e-05 24.3 1.4 4.7e-05 23.9 1.4 1.1 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KKK45695.1 - 0.032 14.7 5.6 0.038 14.5 5.6 1.2 1 0 0 1 1 1 0 PIN domain STAS PF01740.21 KKK45695.1 - 0.11 12.2 0.4 0.63 9.7 0.2 1.9 2 0 0 2 2 2 0 STAS domain DUF148 PF02520.17 KKK45696.1 - 0.0081 16.3 0.6 0.0089 16.1 0.5 1.2 1 1 0 1 1 1 1 Domain of unknown function DUF148 B PF02216.16 KKK45696.1 - 0.086 12.8 0.7 0.11 12.5 0.7 1.3 1 0 0 1 1 1 0 B domain ADD_ATRX PF17981.1 KKK45697.1 - 0.015 15.1 0.2 0.027 14.4 0.2 1.4 1 0 0 1 1 1 0 Cysteine Rich ADD domain PIN PF01850.21 KKK45700.1 - 4.7e-08 33.6 0.5 5.5e-08 33.3 0.5 1.0 1 0 0 1 1 1 1 PIN domain Fer4_7 PF12838.7 KKK45702.1 - 0.0016 19.0 1.8 0.034 14.8 0.6 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45702.1 - 0.022 14.9 2.0 0.022 14.9 2.0 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45702.1 - 0.058 13.5 6.5 0.06 13.4 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 KKK45702.1 - 0.16 12.1 6.5 0.42 10.8 1.7 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45702.1 - 0.48 11.4 8.8 0.46 11.4 1.7 2.9 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK45702.1 - 6.7 6.9 9.0 2.5 8.3 0.4 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45702.1 - 7.1 7.0 8.0 1.2 9.3 1.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 KKK45702.1 - 10 6.2 10.1 0.25 11.2 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Chordopox_A13L PF05961.11 KKK45703.1 - 0.012 15.8 1.2 0.012 15.8 1.2 1.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein ThrE PF06738.12 KKK45703.1 - 0.043 13.2 4.2 0.056 12.8 4.2 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter Phage_holin_3_6 PF07332.11 KKK45703.1 - 0.11 12.6 3.3 0.13 12.3 3.3 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 KKK45703.1 - 0.35 9.6 7.3 0.39 9.4 7.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5385 PF17359.2 KKK45703.1 - 1.1 8.8 6.1 0.12 12.0 2.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5385) CcmD PF04995.14 KKK45703.1 - 1.3 9.2 6.6 0.39 10.8 1.6 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DHHC PF01529.20 KKK45703.1 - 3.7 7.7 6.5 4.6 7.3 6.5 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF4083 PF13314.6 KKK45703.1 - 4.1 7.4 11.3 0.75 9.8 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) CD34_antigen PF06365.12 KKK45703.1 - 7.1 6.1 6.6 0.55 9.8 0.6 1.8 2 0 0 2 2 2 0 CD34/Podocalyxin family Cdd1 PF11731.8 KKK45704.1 - 0.00062 20.0 0.0 0.00067 19.9 0.0 1.1 1 0 0 1 1 1 1 Pathogenicity locus HHH_5 PF14520.6 KKK45704.1 - 0.0014 19.2 0.4 0.0017 18.9 0.4 1.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.6 KKK45704.1 - 0.0075 16.5 0.0 0.0086 16.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) PhoU PF01895.19 KKK45707.1 - 0.16 12.4 2.3 1.9 9.0 0.2 2.5 3 0 0 3 3 3 0 PhoU domain FtsJ PF01728.19 KKK45708.1 - 1.7e-10 41.3 0.0 2.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 KKK45708.1 - 1.5e-07 31.0 0.2 4.1e-07 29.6 0.2 1.8 1 0 0 1 1 1 1 S4 domain Fibrillarin PF01269.17 KKK45708.1 - 0.0032 16.6 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin Methyltransf_11 PF08241.12 KKK45708.1 - 0.08 13.6 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF362 PF04015.12 KKK45709.1 - 2.9e-19 70.1 0.0 4.7e-12 46.6 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF362) PV_NSP1 PF12433.8 KKK45709.1 - 0.073 13.4 0.6 0.35 11.2 0.1 2.4 3 0 0 3 3 3 0 Parvovirus non-structural protein 1 Pex24p PF06398.11 KKK45710.1 - 0.26 10.2 9.2 1.3 7.9 9.2 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF4713 PF15831.5 KKK45710.1 - 1.1 9.8 14.8 0.12 12.8 2.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4713) FA_desaturase PF00487.24 KKK45710.1 - 1.7 8.4 9.7 3.4 7.4 5.2 2.0 1 1 0 2 2 2 0 Fatty acid desaturase Peptidase_M28 PF04389.17 KKK45711.1 - 1.6e-19 70.4 0.0 1.4e-16 60.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M28 DUF2551 PF10826.8 KKK45711.1 - 0.058 13.6 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) ABC_tran PF00005.27 KKK45712.1 - 6.3e-31 107.7 0.6 2.4e-28 99.3 0.6 2.3 1 1 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 KKK45712.1 - 1.9e-16 60.3 0.1 3.8e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KKK45712.1 - 1.7e-07 31.3 1.7 1.1e-05 25.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK45712.1 - 5.7e-05 22.6 0.7 0.00064 19.2 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KKK45712.1 - 0.00019 21.9 3.4 0.027 14.9 0.7 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KKK45712.1 - 0.0011 18.5 0.8 0.05 13.0 0.1 2.4 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 KKK45712.1 - 0.0017 18.6 2.3 1 9.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 KKK45712.1 - 0.026 14.2 0.1 0.053 13.2 0.1 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 KKK45712.1 - 0.04 13.9 1.2 0.87 9.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) FAA_hydrolase_N PF09298.11 KKK45712.1 - 0.066 13.4 0.4 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal NB-ARC PF00931.22 KKK45712.1 - 0.067 12.4 0.2 0.15 11.2 0.2 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.6 KKK45712.1 - 0.093 11.4 0.2 0.37 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KKK45712.1 - 0.11 12.8 0.0 1.3 9.3 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KKK45712.1 - 0.12 12.0 0.1 9.3 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK45712.1 - 0.24 11.8 1.2 1 9.7 1.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KKK45712.1 - 0.54 10.7 5.3 5.6 7.4 5.3 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KKK45713.1 - 1e-27 97.3 0.3 1.5e-12 48.2 0.1 2.2 1 1 1 2 2 2 2 ABC transporter oligo_HPY PF08352.12 KKK45713.1 - 1.8e-21 76.4 0.1 4.2e-21 75.2 0.1 1.7 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 KKK45713.1 - 6.7e-06 26.1 0.9 6.4e-05 22.9 0.9 2.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system tRNA_lig_kinase PF08303.11 KKK45713.1 - 0.0014 18.8 3.4 0.27 11.3 1.4 2.7 2 1 1 3 3 3 2 tRNA ligase kinase domain AAA_22 PF13401.6 KKK45713.1 - 0.022 15.0 0.7 0.39 11.0 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 KKK45713.1 - 0.057 13.8 0.9 0.12 12.8 0.2 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KKK45713.1 - 0.11 12.2 0.1 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 KKK45713.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain YkyA PF10368.9 KKK45713.1 - 0.21 11.2 10.9 0.41 10.3 10.9 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4461 PF14688.6 KKK45713.1 - 0.7 9.6 3.7 0.38 10.5 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4461) DUF87 PF01935.17 KKK45713.1 - 0.74 9.9 6.1 1.5 8.9 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KKK45713.1 - 1.1 9.7 15.0 0.89 10.0 8.9 2.4 2 1 0 2 2 2 0 AAA domain DUF2508 PF10704.9 KKK45713.1 - 2 8.6 13.2 0.46 10.7 3.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) BPD_transp_1 PF00528.22 KKK45714.1 - 6e-32 110.9 11.0 6e-32 110.9 11.0 2.3 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 KKK45714.1 - 0.0065 16.4 0.2 0.0065 16.4 0.2 3.6 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C UPF0093 PF03653.13 KKK45714.1 - 0.68 10.2 4.7 4 7.7 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) DUF3671 PF12420.8 KKK45714.1 - 3.7 7.6 9.7 4.2 7.5 4.0 3.0 1 1 1 2 2 2 0 Protein of unknown function Sigma_reg_N PF13800.6 KKK45714.1 - 5.4 7.4 16.8 0.095 13.0 1.3 3.2 3 1 1 4 4 4 0 Sigma factor regulator N-terminal BPD_transp_1 PF00528.22 KKK45715.1 - 1.7e-41 142.0 5.5 1.7e-41 142.0 5.5 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 KKK45718.1 - 1.7e-55 188.5 2.7 2.4e-55 188.0 2.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle UbiA PF01040.18 KKK45720.1 - 3.5e-21 75.7 8.9 5.2e-21 75.1 8.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family EI24 PF07264.11 KKK45720.1 - 1.1 9.5 15.8 8.3 6.6 15.9 2.3 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Peptidase_M48 PF01435.18 KKK45721.1 - 1.5e-15 57.5 0.0 2.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KKK45721.1 - 1.6e-05 24.3 0.2 3.9e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 BlaR1 peptidase M56 FrhB_FdhB_C PF04432.13 KKK45725.1 - 1.2e-36 125.8 0.5 3.9e-36 124.2 0.1 2.1 2 0 0 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 KKK45725.1 - 7.4e-24 83.7 0.0 1.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term TrmB PF01978.19 KKK45725.1 - 5.5e-11 42.2 0.0 1.4e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fer4_10 PF13237.6 KKK45725.1 - 0.00031 20.8 8.3 0.0047 17.0 0.5 2.8 3 0 0 3 3 3 2 4Fe-4S dicluster domain HTH_27 PF13463.6 KKK45725.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Fer4 PF00037.27 KKK45725.1 - 0.0012 18.5 1.0 0.0012 18.5 1.0 3.1 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_7 PF12838.7 KKK45725.1 - 0.0017 18.9 2.7 0.034 14.7 0.1 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45725.1 - 0.004 17.1 2.2 0.004 17.1 2.2 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45725.1 - 0.014 16.3 5.7 0.74 10.8 0.2 3.7 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 KKK45725.1 - 0.019 15.0 0.7 0.019 15.0 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 KKK45725.1 - 0.021 15.0 12.6 0.033 14.4 1.6 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain HTH_36 PF13730.6 KKK45725.1 - 0.083 12.9 0.4 0.24 11.4 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain Fer4_8 PF13183.6 KKK45725.1 - 0.083 13.3 5.7 0.17 12.4 0.3 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain CPSase_L_D3 PF02787.19 KKK45725.1 - 0.11 12.9 0.3 0.3 11.4 0.3 1.8 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain LRR_8 PF13855.6 KKK45725.1 - 0.2 11.5 3.7 5.2 6.9 0.8 3.0 2 0 0 2 2 2 0 Leucine rich repeat Fer4_17 PF13534.6 KKK45725.1 - 0.22 12.1 8.4 0.32 11.6 0.6 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK45725.1 - 0.23 12.0 6.0 1.7 9.3 1.3 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KKK45725.1 - 1.1 10.4 12.0 3.7 8.7 3.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 KKK45725.1 - 1.5 9.0 9.3 1.2 9.4 2.6 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain LRR_4 PF12799.7 KKK45725.1 - 6 7.4 9.4 4.6 7.8 0.6 3.5 4 0 0 4 4 2 0 Leucine Rich repeats (2 copies) Succ_CoA_lig PF13607.6 KKK45726.1 - 6.9e-40 136.1 0.1 3.8e-39 133.6 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK45726.1 - 7.1e-16 58.7 0.0 1.8e-15 57.5 0.0 1.6 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 KKK45726.1 - 1.1e-10 42.0 0.1 3.1e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain Transposase_mut PF00872.18 KKK45730.1 - 0.0026 16.7 1.1 0.0034 16.3 0.1 1.7 2 0 0 2 2 2 1 Transposase, Mutator family MULE PF10551.9 KKK45730.1 - 0.083 13.3 0.1 0.28 11.6 0.1 2.0 1 0 0 1 1 1 0 MULE transposase domain Chorismate_bind PF00425.18 KKK45731.1 - 1.7e-85 286.7 0.0 8.7e-85 284.4 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KKK45731.1 - 5.1e-17 62.4 1.1 2.5e-15 56.9 0.3 2.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region RbcS PF12338.8 KKK45731.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit GATase PF00117.28 KKK45732.1 - 1.5e-45 155.3 0.1 1.8e-45 155.1 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KKK45732.1 - 1.9e-13 50.7 0.0 2.5e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 ParE_toxin PF05016.15 KKK45734.1 - 1e-07 32.4 0.6 1.1e-07 32.4 0.6 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Herpes_UL51 PF04540.13 KKK45735.1 - 0.042 13.6 0.0 0.048 13.4 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL51 protein ParE_toxin PF05016.15 KKK45736.1 - 6.4e-14 52.3 0.0 7e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE DUF1241 PF06840.11 KKK45736.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Fer4_7 PF12838.7 KKK45737.1 - 2.8e-05 24.6 4.2 0.0028 18.2 0.2 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45737.1 - 0.00025 21.2 4.7 0.021 15.0 1.9 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45737.1 - 0.00076 19.2 1.7 0.00076 19.2 1.7 3.3 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_16 PF13484.6 KKK45737.1 - 0.0013 19.6 8.5 0.0013 19.6 8.5 2.5 2 1 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK45737.1 - 0.0057 16.7 12.1 0.0068 16.5 2.5 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45737.1 - 0.0063 16.9 4.3 0.44 11.0 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK45737.1 - 0.035 14.3 3.8 5 7.4 2.8 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK45737.1 - 0.095 13.3 8.6 0.21 12.1 1.5 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_19 PF06902.11 KKK45737.1 - 0.12 12.5 4.3 0.12 12.4 0.1 2.8 3 0 0 3 3 3 0 Divergent 4Fe-4S mono-cluster Fer4_21 PF14697.6 KKK45737.1 - 1.6 8.9 11.8 0.3 11.2 1.2 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45737.1 - 2.6 8.3 13.7 0.31 11.2 3.5 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 KKK45737.1 - 7 7.8 20.2 3.7 8.7 1.1 3.8 4 0 0 4 4 4 0 4Fe-4S binding domain HisKA_7TM PF16927.5 KKK45738.1 - 0.18 11.8 29.8 0.074 13.1 13.3 2.0 1 1 1 2 2 2 0 N-terminal 7TM region of histidine kinase UPF0175 PF03683.13 KKK45739.1 - 1.9e-06 27.5 0.0 6.1e-05 22.7 0.0 2.2 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0175) RHH_1 PF01402.21 KKK45739.1 - 5.8e-05 22.9 1.7 0.00038 20.3 0.3 2.7 3 0 0 3 3 3 1 Ribbon-helix-helix protein, copG family TAL_FSA PF00923.19 KKK45739.1 - 0.016 14.6 0.1 0.018 14.4 0.1 1.0 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase PPR_2 PF13041.6 KKK45739.1 - 0.023 14.9 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family HTH_23 PF13384.6 KKK45739.1 - 0.031 14.1 0.2 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain RHH_3 PF12651.7 KKK45739.1 - 0.053 13.5 0.3 0.15 12.1 0.2 1.8 1 1 0 1 1 1 0 Ribbon-helix-helix domain HTH_28 PF13518.6 KKK45739.1 - 0.058 13.5 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_8 PF02954.19 KKK45739.1 - 0.066 13.0 0.0 0.066 13.0 0.0 2.3 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family Glutaredoxin PF00462.24 KKK45740.1 - 0.047 13.9 0.1 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin HATPase_c PF02518.26 KKK45741.1 - 1e-20 74.3 1.2 3.1e-20 72.8 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK45741.1 - 2.6e-11 43.4 0.0 5.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KKK45741.1 - 3.4e-05 24.0 0.1 8.8e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KKK45741.1 - 4.6e-05 23.6 0.0 8.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KKK45741.1 - 0.094 12.7 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 KKK45741.1 - 0.15 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 PAS domain Response_reg PF00072.24 KKK45742.1 - 4.5e-22 78.3 0.0 8.5e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKK45742.1 - 0.0024 17.9 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF2420 PF10336.9 KKK45744.1 - 0.014 15.4 3.1 0.03 14.3 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2420) Imm7 PF15585.6 KKK45744.1 - 0.18 12.1 0.3 0.22 11.8 0.3 1.1 1 0 0 1 1 1 0 Immunity protein 7 DNTTIP1_dimer PF18192.1 KKK45745.1 - 0.072 13.4 0.3 0.41 11.0 0.0 2.1 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain MCPsignal PF00015.21 KKK45746.1 - 9.9e-35 119.9 29.0 7.9e-34 116.9 16.2 2.7 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 KKK45746.1 - 3.5e-08 33.7 0.3 1.7e-06 28.3 0.0 3.4 3 0 0 3 3 3 1 HAMP domain Sigma70_ner PF04546.13 KKK45746.1 - 0.068 13.1 4.8 0.05 13.5 1.6 2.0 1 1 1 2 2 2 0 Sigma-70, non-essential region Yuri_gagarin PF15934.5 KKK45746.1 - 0.071 12.9 3.9 0.067 13.0 2.5 1.6 1 1 0 1 1 1 0 Yuri gagarin BAR PF03114.18 KKK45746.1 - 0.23 11.1 7.9 2.2 7.9 0.9 2.7 2 1 0 2 2 2 0 BAR domain DUF948 PF06103.11 KKK45746.1 - 0.23 11.7 22.5 5.1 7.4 3.9 4.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Sigma_reg_N PF13800.6 KKK45746.1 - 0.29 11.5 2.8 10 6.5 0.2 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal T7SS_ESX_EspC PF10824.8 KKK45746.1 - 0.94 10.0 15.0 0.11 12.9 2.1 3.5 3 1 1 4 4 3 0 Excreted virulence factor EspC, type VII ESX diderm HIP1_clath_bdg PF16515.5 KKK45746.1 - 1.1 10.0 7.9 9 7.0 1.4 3.0 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fzo_mitofusin PF04799.13 KKK45746.1 - 2.6 7.6 7.9 6.5 6.3 0.2 2.8 2 1 1 3 3 3 0 fzo-like conserved region Sec34 PF04136.15 KKK45746.1 - 2.6 7.9 10.8 1.3 8.9 0.6 2.9 2 1 0 2 2 2 0 Sec34-like family GldM_N PF12081.8 KKK45746.1 - 2.8 8.0 12.4 0.5 10.4 0.6 2.7 1 1 1 3 3 3 0 GldM N-terminal domain DUF2203 PF09969.9 KKK45746.1 - 2.8 8.7 6.6 8.3 7.2 1.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) ADIP PF11559.8 KKK45746.1 - 3.8 7.6 12.9 1.5 8.9 3.4 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KKK45746.1 - 8.5 6.7 10.7 0.48 10.8 2.5 2.6 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 KKK45746.1 - 9.6 6.5 12.8 14 5.9 3.7 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 KKK45746.1 - 9.9 6.3 14.5 15 5.8 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-C4H2 PF10146.9 KKK45746.1 - 9.9 6.4 11.4 11 6.3 3.3 2.3 1 1 0 2 2 2 0 Zinc finger-containing protein YdjM PF04307.14 KKK45747.1 - 4.1e-19 68.5 7.9 5.8e-19 68.0 7.9 1.2 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase DUF362 PF04015.12 KKK45749.1 - 5.3e-28 98.6 0.0 6.7e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF362) FAD_binding_3 PF01494.19 KKK45750.1 - 3.5e-07 29.8 0.0 0.0072 15.6 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 KKK45750.1 - 0.00087 19.5 0.2 0.0021 18.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KKK45750.1 - 0.0025 17.1 0.0 0.0047 16.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KKK45750.1 - 0.056 12.5 0.0 6.8 5.6 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KKK45750.1 - 0.083 12.1 0.1 1.8 7.7 0.0 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 KKK45751.1 - 4.7e-09 36.5 0.0 6.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Phage_int_SAM_5 PF13102.6 KKK45751.1 - 0.043 14.1 2.5 0.078 13.3 0.3 2.4 2 1 0 2 2 2 0 Phage integrase SAM-like domain Lactamase_B_2 PF12706.7 KKK45751.1 - 0.061 12.8 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PP_kinase_N PF13089.6 KKK45751.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain PrsW-protease PF13367.6 KKK45751.1 - 0.22 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease Apolipoprotein PF01442.18 KKK45752.1 - 0.021 14.7 4.1 0.28 11.0 0.4 2.7 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF3450 PF11932.8 KKK45752.1 - 0.028 13.7 0.1 0.028 13.7 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) TrmB PF01978.19 KKK45752.1 - 0.031 14.2 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB dCache_3 PF14827.6 KKK45752.1 - 0.055 13.1 1.1 0.86 9.2 0.1 2.4 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase CENP-F_leu_zip PF10473.9 KKK45752.1 - 0.32 11.0 17.4 0.55 10.2 6.3 3.8 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_M75 PF09375.10 KKK45752.1 - 0.44 10.0 7.0 0.36 10.3 1.4 2.5 1 1 1 2 2 2 0 Imelysin DUF4358 PF14270.6 KKK45752.1 - 1.1 9.6 8.3 1.5 9.1 0.2 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4358) Myb_DNA-bind_3 PF12776.7 KKK45752.1 - 1.4 9.9 6.5 7.1 7.7 0.1 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF883 PF05957.13 KKK45752.1 - 1.7 9.3 4.7 37 5.0 0.0 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) RB_A PF01858.17 KKK45752.1 - 4.5 7.0 9.3 0.52 10.1 0.3 3.5 3 1 0 3 3 3 0 Retinoblastoma-associated protein A domain Csm2_III-A PF03750.13 KKK45752.1 - 4.6 8.1 16.0 0.089 13.6 1.7 4.1 2 1 1 3 3 3 0 Csm2 Type III-A DUF4115 PF13464.6 KKK45754.1 - 0.047 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) EBV-NA3 PF05009.12 KKK45754.1 - 0.073 12.6 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Asp_protease PF09668.10 KKK45754.1 - 0.11 12.3 0.1 0.41 10.4 0.0 2.0 1 1 0 1 1 1 0 Aspartyl protease HTH_47 PF16221.5 KKK45757.1 - 9.4e-05 21.9 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 winged helix-turn-helix TrmB PF01978.19 KKK45757.1 - 0.015 15.1 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4535 PF15054.6 KKK45757.1 - 0.12 12.1 0.1 0.65 9.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) SapB_1 PF05184.15 KKK45757.1 - 9.5 6.4 7.8 13 5.9 0.4 3.0 2 1 1 3 3 3 0 Saposin-like type B, region 1 DUF1610 PF07754.11 KKK45758.1 - 4.1e-08 33.0 4.8 6.2e-08 32.5 4.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1610) C1_2 PF03107.16 KKK45758.1 - 2.2e-05 24.7 8.4 0.044 14.1 2.6 2.1 1 1 1 2 2 2 2 C1 domain HscB_4_cys PF18256.1 KKK45758.1 - 0.0018 18.0 4.1 0.0018 18.0 4.1 2.6 3 0 0 3 3 3 1 Co-chaperone HscB tetracysteine metal binding motif DZR PF12773.7 KKK45758.1 - 0.034 14.2 10.3 0.039 14.0 5.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf_C2H2_13 PF18508.1 KKK45758.1 - 0.19 11.3 0.1 0.19 11.3 0.1 2.3 3 0 0 3 3 3 0 Zinc finger domain Cript PF10235.9 KKK45758.1 - 0.36 11.4 0.5 0.36 11.4 0.5 2.3 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT zf_UBZ PF18439.1 KKK45758.1 - 0.64 9.7 11.1 4.3 7.0 0.6 3.9 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger DUF2797 PF10977.8 KKK45758.1 - 1.4 8.8 5.3 1.5 8.7 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) HypA PF01155.19 KKK45758.1 - 1.4 8.9 7.1 0.97 9.5 2.9 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KKK45758.1 - 1.6 8.8 7.6 0.22 11.5 0.8 2.3 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein PolC_DP2 PF03833.13 KKK45758.1 - 1.7 6.4 3.7 1.6 6.5 3.7 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2752 PF10825.8 KKK45758.1 - 7.3 6.7 11.9 0.24 11.5 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2752) NRDD PF13597.6 KKK45758.1 - 7.9 5.1 8.3 4.7 5.9 3.5 1.9 1 1 1 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase ZZ PF00569.17 KKK45758.1 - 8.1 6.4 10.8 12 5.8 4.4 2.8 1 1 2 3 3 3 0 Zinc finger, ZZ type zf-H2C2_2 PF13465.6 KKK45758.1 - 9.3 6.9 9.2 11 6.7 0.3 3.0 1 1 1 2 2 2 0 Zinc-finger double domain EF1_GNE PF00736.19 KKK45759.1 - 2.7e-12 46.7 0.0 2.9e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain MutL_C PF08676.11 KKK45760.1 - 4e-35 120.7 0.0 8e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KKK45760.1 - 1.1e-14 54.1 0.1 2.2e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF5590 PF17881.1 KKK45760.1 - 0.023 14.8 1.3 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) HAND PF09110.11 KKK45760.1 - 0.058 14.2 1.7 0.14 12.9 1.7 1.6 1 0 0 1 1 1 0 HAND ECH_1 PF00378.20 KKK45762.1 - 2.5e-14 53.2 0.0 2.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK45762.1 - 6.2e-14 52.2 0.0 6.9e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH_N PF02737.18 KKK45763.1 - 1.7e-53 181.2 0.1 2.4e-53 180.7 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KKK45763.1 - 6.8e-16 58.7 0.0 1.8e-10 41.3 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AlaDh_PNT_C PF01262.21 KKK45763.1 - 0.004 16.5 1.8 0.0045 16.3 1.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KKK45763.1 - 0.0048 17.1 6.0 0.013 15.6 4.3 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KKK45763.1 - 0.017 14.7 0.8 0.03 13.9 0.8 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KKK45763.1 - 0.02 14.9 0.7 0.037 14.0 0.2 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 KKK45763.1 - 0.027 13.7 0.1 0.041 13.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3479 PF11965.8 KKK45763.1 - 0.031 14.4 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) NAD_binding_7 PF13241.6 KKK45763.1 - 0.054 13.9 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.6 KKK45763.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Shikimate_DH PF01488.20 KKK45763.1 - 0.15 12.1 1.2 0.63 10.1 0.2 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PALP PF00291.25 KKK45763.1 - 0.16 11.4 0.0 6 6.2 0.0 2.4 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 KKK45763.1 - 0.24 11.7 1.3 0.33 11.2 0.3 1.8 2 0 0 2 2 2 0 TrkA-N domain THF_DHG_CYH_C PF02882.19 KKK45763.1 - 1.1 8.6 5.1 6.6 6.0 0.5 2.7 1 1 2 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LMWPc PF01451.21 KKK45765.1 - 1.3e-24 87.1 0.0 1.6e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Sa_NUDIX PF18167.1 KKK45765.1 - 2.4e-05 24.3 1.6 3.1e-05 23.9 1.6 1.1 1 0 0 1 1 1 1 SMODS-associated NUDIX domain MFS_1 PF07690.16 KKK45766.1 - 0.011 14.7 47.4 0.047 12.6 17.4 3.0 1 1 2 3 3 3 0 Major Facilitator Superfamily adh_short PF00106.25 KKK45767.1 - 6.5e-37 126.9 0.0 8e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK45767.1 - 4e-30 105.1 0.0 5.4e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK45767.1 - 5.1e-10 39.5 0.0 1.4e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KKK45767.1 - 0.00025 20.3 0.1 0.003 16.7 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KKK45767.1 - 0.00034 20.2 0.0 0.002 17.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KKK45767.1 - 0.0056 16.6 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF501 PF04417.12 KKK45767.1 - 0.0068 16.2 0.3 0.017 14.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF501) 2-Hacid_dh_C PF02826.19 KKK45767.1 - 0.025 13.9 0.0 0.072 12.5 0.0 1.8 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KKK45767.1 - 0.027 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 KKK45767.1 - 0.071 12.2 0.0 0.27 10.3 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 KKK45767.1 - 0.08 11.9 0.1 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1319 PF07028.11 KKK45767.1 - 0.089 13.0 0.5 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) TPR_12 PF13424.6 KKK45768.1 - 4.3e-59 196.7 17.9 1.1e-13 51.2 0.1 6.5 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 KKK45768.1 - 3.9e-40 134.1 44.2 1.3e-05 24.8 0.0 10.9 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 KKK45768.1 - 1.4e-39 131.0 29.9 0.00047 20.1 0.1 10.7 10 1 0 10 10 10 10 Tetratricopeptide repeat TPR_7 PF13176.6 KKK45768.1 - 4.6e-26 88.9 28.7 0.0012 18.7 0.0 10.9 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_MalT PF17874.1 KKK45768.1 - 1.3e-21 77.3 0.0 8.2e-10 38.6 0.0 4.2 1 1 3 4 4 4 4 MalT-like TPR region TPR_8 PF13181.6 KKK45768.1 - 1.3e-19 68.7 40.2 0.0099 16.0 0.2 11.1 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_10 PF13374.6 KKK45768.1 - 1.5e-19 69.2 30.5 0.00098 18.9 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KKK45768.1 - 6.2e-17 61.0 40.2 0.0044 16.7 0.2 9.7 10 0 0 10 10 10 7 TPR repeat SNAP PF14938.6 KKK45768.1 - 1.5e-15 57.4 7.8 0.0041 16.6 1.4 5.1 3 1 2 5 5 5 4 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 KKK45768.1 - 1e-11 45.2 5.2 0.012 16.3 0.0 7.3 7 2 0 7 7 7 2 Tetratricopeptide repeat MIT PF04212.18 KKK45768.1 - 1.3e-10 41.1 33.5 0.0042 17.1 0.6 9.4 8 2 2 10 10 10 3 MIT (microtubule interacting and transport) domain SIR2_2 PF13289.6 KKK45768.1 - 2.5e-08 34.1 0.2 1.9e-07 31.3 0.1 2.6 2 0 0 2 2 1 1 SIR2-like domain TPR_15 PF13429.6 KKK45768.1 - 1.1e-06 28.1 0.1 0.29 10.3 0.0 4.3 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KKK45768.1 - 1.4e-06 28.5 8.4 22 6.0 0.0 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KKK45768.1 - 4e-06 27.2 3.9 22 6.2 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_21 PF09976.9 KKK45768.1 - 0.00011 22.0 7.6 0.51 10.0 0.0 4.9 3 2 3 6 6 6 2 Tetratricopeptide repeat-like domain SHNi-TPR PF10516.9 KKK45768.1 - 0.00011 21.6 16.6 0.42 10.1 0.0 7.4 8 0 0 8 8 8 2 SHNi-TPR DUF627 PF04781.12 KKK45768.1 - 0.00023 21.1 2.2 38 4.4 0.0 5.7 3 2 3 6 6 6 0 Protein of unknown function (DUF627) RPN7 PF10602.9 KKK45768.1 - 0.00091 19.0 5.5 0.23 11.1 1.4 3.1 1 1 0 2 2 2 2 26S proteasome subunit RPN7 TPR_17 PF13431.6 KKK45768.1 - 0.0035 17.6 14.3 57 4.4 0.0 8.8 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 KKK45768.1 - 0.0039 17.7 14.4 1.4 9.5 0.2 6.0 5 1 0 5 5 5 1 Tetratricopeptide repeat SRP68 PF16969.5 KKK45768.1 - 0.017 14.2 0.4 1.6 7.6 0.0 3.6 2 2 2 4 4 4 0 RNA-binding signal recognition particle 68 TPR_9 PF13371.6 KKK45768.1 - 0.042 14.0 0.5 26 5.1 0.0 4.8 4 2 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KKK45768.1 - 0.11 12.6 0.1 0.11 12.6 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF5113 PF17140.4 KKK45768.1 - 0.61 9.9 12.9 1.3 8.9 0.0 5.6 7 2 2 9 9 7 0 Domain of unknown function (DUF5113) ANAPC3 PF12895.7 KKK45768.1 - 0.98 9.7 10.4 51 4.2 0.3 5.4 4 3 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 FAD_binding_2 PF00890.24 KKK45769.1 - 5.9e-88 295.7 0.0 7.1e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KKK45769.1 - 1.5e-11 44.4 0.0 4.4e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 KKK45769.1 - 2.9e-06 27.1 0.0 4.8e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KKK45769.1 - 0.0043 16.3 0.0 0.05 12.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK45769.1 - 0.0082 15.4 0.0 0.03 13.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KKK45769.1 - 0.01 16.1 0.1 0.042 14.1 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KKK45769.1 - 0.037 13.3 0.0 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 KKK45769.1 - 0.18 10.3 0.0 0.32 9.5 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) DUF2877 PF11392.8 KKK45770.1 - 1.8e-25 89.8 0.1 2.9e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2877) Top6b_C PF18000.1 KKK45770.1 - 0.0077 16.4 1.4 2 8.6 0.0 2.9 2 1 1 3 3 3 2 Type 2 DNA topoisomerase 6 subunit B C-terminal domain ABC_tran PF00005.27 KKK45771.1 - 3.5e-05 24.3 0.0 7.1e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter DNA_pol3_delta2 PF13177.6 KKK45771.1 - 0.13 12.0 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DsbD PF02683.15 KKK45775.1 - 9.8e-15 55.0 2.4 1.1e-14 54.9 2.4 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 KKK45775.1 - 2.1e-06 27.8 3.5 2.7e-06 27.5 3.5 1.3 1 1 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region adh_short PF00106.25 KKK45778.1 - 1e-37 129.5 0.0 1.2e-36 126.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK45778.1 - 3.3e-27 95.6 0.0 2.3e-26 92.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK45778.1 - 2.1e-10 40.8 0.0 3.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 KR domain LDcluster4 PF18306.1 KKK45778.1 - 0.00012 21.7 0.1 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Epimerase PF01370.21 KKK45778.1 - 0.00022 20.8 0.0 0.00064 19.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK45778.1 - 0.027 13.9 0.0 0.046 13.1 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pyr_redox_3 PF13738.6 KKK45778.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_8 PF13183.6 KKK45779.1 - 0.0018 18.7 2.3 0.045 14.2 0.7 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK45779.1 - 0.03 14.4 3.8 0.03 14.4 3.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 KKK45779.1 - 0.049 14.2 8.3 0.12 13.0 3.0 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45779.1 - 0.15 12.3 7.0 0.23 11.6 2.8 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45779.1 - 0.26 12.2 7.8 0.38 11.7 2.1 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK45779.1 - 0.74 10.0 8.9 0.98 9.6 2.9 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Glyoxalase PF00903.25 KKK45780.1 - 3e-12 46.9 0.0 1e-11 45.1 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKK45780.1 - 4.9e-06 26.8 0.0 8.4e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KKK45780.1 - 0.0081 16.1 0.0 1.7 8.6 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KKK45780.1 - 0.062 13.4 0.0 0.092 12.9 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain UBA_5 PF16577.5 KKK45780.1 - 0.1 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 UBA domain FTSW_RODA_SPOVE PF01098.19 KKK45781.1 - 0.28 10.1 7.6 0.31 10.0 7.6 1.0 1 0 0 1 1 1 0 Cell cycle protein DUF4191 PF13829.6 KKK45781.1 - 0.84 8.9 2.2 0.81 9.0 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2070 PF09843.9 KKK45781.1 - 2.4 6.4 8.4 2.4 6.3 8.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UPF0242 PF06785.11 KKK45781.1 - 6.3 6.9 5.9 7.1 6.7 5.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Radical_SAM PF04055.21 KKK45782.1 - 5e-10 40.0 0.0 3.5e-09 37.3 0.0 2.0 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KKK45782.1 - 1.9e-06 28.0 0.2 8.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK45782.1 - 7.6e-06 26.2 0.1 2.2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain DUF4332 PF14229.6 KKK45783.1 - 2.1e-19 70.0 0.0 4.5e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) Cdd1 PF11731.8 KKK45783.1 - 0.0058 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus Peptidase_M4 PF01447.18 KKK45783.1 - 0.034 14.6 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain DUF362 PF04015.12 KKK45787.1 - 0.032 14.5 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Stevor PF17410.2 KKK45787.1 - 0.058 12.9 0.0 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Fer4 PF00037.27 KKK45788.1 - 4.3e-07 29.5 12.0 0.00015 21.4 1.3 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK45788.1 - 1.2e-06 28.5 11.3 1.2e-06 28.5 11.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45788.1 - 2.7e-06 27.8 22.1 3.8e-05 24.2 12.0 2.9 1 1 3 4 4 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45788.1 - 5.3e-06 26.3 11.8 0.00046 20.1 2.6 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK45788.1 - 1.8e-05 24.8 12.0 1.8e-05 24.8 12.0 2.8 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45788.1 - 0.0013 19.6 14.8 0.022 15.7 0.6 3.5 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK45788.1 - 0.0023 18.0 25.1 0.0098 16.0 0.8 3.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45788.1 - 0.019 15.4 0.4 0.019 15.4 0.4 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK45788.1 - 0.036 14.8 13.6 0.9 10.3 3.2 2.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 KKK45788.1 - 0.037 14.5 2.8 0.037 14.5 2.8 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain SLAC1 PF03595.17 KKK45789.1 - 6.3e-31 107.8 38.4 7.7e-31 107.6 38.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3795 PF12675.7 KKK45791.1 - 0.023 15.1 12.8 0.071 13.5 12.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) ABM PF03992.16 KKK45792.1 - 0.00019 21.4 0.0 0.00026 21.0 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase CoA_trans PF01144.23 KKK45793.1 - 4.2e-24 85.1 0.1 5.2e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 KKK45794.1 - 4.6e-20 72.0 0.0 8.1e-20 71.1 0.0 1.3 1 1 0 1 1 1 1 Coenzyme A transferase TPR_MalT PF17874.1 KKK45795.1 - 1e-13 51.4 1.9 8e-08 32.0 0.0 3.5 1 1 1 3 3 3 3 MalT-like TPR region TPR_12 PF13424.6 KKK45795.1 - 3.9e-13 49.5 7.6 4.9e-07 30.0 0.0 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KKK45795.1 - 6.2e-08 32.1 23.8 0.011 15.6 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KKK45795.1 - 1.9e-07 30.7 3.1 0.17 11.6 0.0 4.8 5 0 0 5 5 5 2 TPR repeat TPR_10 PF13374.6 KKK45795.1 - 1.7e-05 24.5 5.8 1 9.3 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KKK45795.1 - 6.4e-05 22.8 28.3 0.33 11.2 0.1 9.2 10 1 1 11 11 11 2 Tetratricopeptide repeat TPR_21 PF09976.9 KKK45795.1 - 0.0017 18.1 4.5 1.5 8.5 0.0 4.9 4 1 1 6 6 6 1 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 KKK45795.1 - 0.0017 18.4 32.1 0.097 12.9 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 KKK45795.1 - 0.0085 16.1 4.1 21 5.4 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF627 PF04781.12 KKK45795.1 - 0.016 15.2 0.2 8.4 6.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) ANAPC3 PF12895.7 KKK45795.1 - 0.037 14.3 12.2 0.77 10.0 0.0 5.6 6 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TAtT PF16811.5 KKK45795.1 - 0.044 13.1 0.2 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 TRAP transporter T-component DUF2062 PF09835.9 KKK45795.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) TPR_17 PF13431.6 KKK45795.1 - 0.073 13.5 4.5 28 5.4 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF1599 PF07659.11 KKK45795.1 - 0.14 12.6 2.0 26 5.4 0.1 3.2 2 1 0 2 2 2 0 Nucleotide modification associated domain 1 PilI PF10623.9 KKK45796.1 - 0.17 12.1 0.0 24 5.2 0.0 2.2 1 1 1 2 2 2 0 Plasmid conjugative transfer protein PilI Rubrerythrin PF02915.17 KKK45799.1 - 3.8e-18 66.2 9.1 5.2e-18 65.8 9.1 1.2 1 0 0 1 1 1 1 Rubrerythrin zf-ribbon_3 PF13248.6 KKK45799.1 - 0.0009 18.6 2.2 0.0016 17.8 2.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain Ferritin PF00210.24 KKK45799.1 - 0.026 14.5 3.5 0.032 14.2 3.5 1.1 1 0 0 1 1 1 0 Ferritin-like domain Methyltransf_13 PF08421.11 KKK45799.1 - 0.032 14.5 0.1 0.11 12.7 0.0 2.0 1 1 0 1 1 1 0 Putative zinc binding domain Zn-ribbon_8 PF09723.10 KKK45799.1 - 0.068 13.3 0.9 0.2 11.8 0.9 1.8 1 0 0 1 1 1 0 Zinc ribbon domain Cys_rich_CPCC PF14206.6 KKK45799.1 - 0.073 12.9 1.7 0.19 11.6 1.0 2.0 2 0 0 2 2 2 0 Cysteine-rich CPCC GRDA PF04723.14 KKK45799.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A RecR PF02132.15 KKK45799.1 - 0.1 12.2 2.5 0.27 10.8 2.5 1.7 1 0 0 1 1 1 0 RecR protein TF_Zn_Ribbon PF08271.12 KKK45799.1 - 0.19 11.2 1.6 12 5.5 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding UPF0547 PF10571.9 KKK45799.1 - 0.44 10.7 3.9 7.5 6.7 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 VIT1 PF01988.19 KKK45800.1 - 1.8e-58 198.0 4.7 2e-58 197.8 4.7 1.0 1 0 0 1 1 1 1 VIT family SLATT_6 PF18169.1 KKK45800.1 - 0.077 12.6 0.3 0.17 11.4 0.3 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 SLATT_1 PF18181.1 KKK45800.1 - 0.1 12.5 0.9 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2427 PF10348.9 KKK45800.1 - 4.4 7.1 8.0 0.83 9.5 0.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) OMPdecase PF00215.24 KKK45801.1 - 5e-11 42.6 0.3 6.6e-11 42.2 0.3 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribul_P_3_epim PF00834.19 KKK45801.1 - 0.001 18.5 0.1 0.002 17.5 0.1 1.5 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KKK45801.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Molybdopterin PF00384.22 KKK45805.1 - 1.2e-20 73.9 0.0 1.2e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Arm-DNA-bind_3 PF13356.6 KKK45805.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain Molydop_binding PF01568.21 KKK45806.1 - 3.3e-08 33.5 0.0 4.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain DUF5615 PF18480.1 KKK45806.1 - 0.13 12.0 0.0 13 5.7 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5615) Fer4 PF00037.27 KKK45807.1 - 1.5e-22 78.4 33.8 6.3e-08 32.1 2.2 4.5 4 1 0 4 4 4 4 4Fe-4S binding domain Fer4_7 PF12838.7 KKK45807.1 - 3.4e-19 69.2 23.8 2e-09 37.9 7.8 2.6 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK45807.1 - 1.8e-16 60.1 21.5 2.8e-09 37.0 5.5 3.0 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45807.1 - 1.7e-15 57.7 15.8 0.00029 21.7 0.7 4.2 4 0 0 4 4 4 4 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK45807.1 - 1.4e-14 53.9 24.0 8.8e-07 28.9 8.8 3.6 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45807.1 - 9.7e-14 51.3 20.6 0.00047 20.2 0.5 4.2 4 0 0 4 4 4 4 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK45807.1 - 8.5e-11 41.4 35.0 5.5e-05 23.1 4.3 4.2 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_2 PF12797.7 KKK45807.1 - 4.8e-09 35.8 33.9 0.00063 19.7 2.1 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_8 PF13183.6 KKK45807.1 - 1.1e-07 32.2 22.1 0.017 15.6 0.6 3.7 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK45807.1 - 2.3e-06 28.2 20.6 0.039 14.7 1.1 4.5 3 1 0 3 3 3 3 4Fe-4S single cluster domain Fer4_3 PF12798.7 KKK45807.1 - 5.2e-06 27.0 45.3 0.0049 17.7 5.8 4.4 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_22 PF17179.4 KKK45807.1 - 4.7e-05 24.2 20.7 0.016 16.0 0.2 4.0 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK45807.1 - 0.00036 20.8 35.3 0.0034 17.8 1.9 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_17 PF13534.6 KKK45807.1 - 0.00067 20.1 28.8 0.083 13.4 11.0 3.8 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK45807.1 - 0.016 15.7 29.1 0.1 13.1 2.1 4.5 4 0 0 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 KKK45807.1 - 0.059 13.5 0.3 0.059 13.5 0.3 2.9 3 0 0 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Glutaredoxin PF00462.24 KKK45807.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.3 3 1 0 3 3 2 0 Glutaredoxin Fer4_18 PF13746.6 KKK45807.1 - 1.7 8.9 24.3 1 9.6 0.3 4.0 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK45808.1 - 1.2e-09 37.6 15.0 4.2e-05 23.2 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK45808.1 - 1.9e-09 37.0 11.1 7.7e-05 22.6 2.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK45808.1 - 5.2e-09 35.8 14.2 4.7e-05 23.3 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK45808.1 - 1.9e-08 34.3 8.0 6.7e-08 32.6 8.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK45808.1 - 3.4e-08 33.5 7.2 0.00026 21.0 1.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK45808.1 - 1.1e-07 32.3 21.5 7.5e-06 26.4 11.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK45808.1 - 1.3e-07 31.6 11.6 1.7e-06 28.0 12.4 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK45808.1 - 1.1e-06 29.1 4.8 0.01 16.3 0.1 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK45808.1 - 4.1e-06 27.6 12.9 0.0016 19.3 1.7 2.3 2 1 1 3 3 3 3 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK45808.1 - 2e-05 24.7 10.2 0.023 15.2 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KKK45808.1 - 3e-05 24.8 5.8 0.023 15.5 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK45808.1 - 0.00014 22.3 8.4 0.00039 20.8 8.5 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK45808.1 - 0.00072 20.2 11.0 0.0078 16.9 0.8 2.4 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.7 KKK45808.1 - 0.0016 19.2 18.0 0.12 13.3 5.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 KKK45808.1 - 0.018 15.6 13.3 4.7 7.8 13.3 2.6 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I AF2331-like PF14556.6 KKK45808.1 - 0.092 13.3 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 AF2331-like Fer4_18 PF13746.6 KKK45808.1 - 0.15 12.3 12.0 0.56 10.4 2.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Prok-RING_1 PF14446.6 KKK45809.1 - 3.7e-05 23.6 3.4 3.7e-05 23.6 3.4 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 VWA PF00092.28 KKK45809.1 - 0.00067 19.9 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zinc_ribbon_15 PF17032.5 KKK45809.1 - 0.0098 16.6 3.4 0.0098 16.6 3.4 3.3 2 1 1 3 3 3 1 zinc-ribbon family UPF0547 PF10571.9 KKK45809.1 - 0.02 15.0 6.0 0.11 12.6 1.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 VWA_2 PF13519.6 KKK45809.1 - 0.02 15.5 0.0 0.04 14.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain C1_2 PF03107.16 KKK45809.1 - 0.044 14.1 1.3 0.044 14.1 1.3 2.8 3 0 0 3 3 3 0 C1 domain zf-ACC PF17848.1 KKK45809.1 - 0.13 12.4 5.8 10 6.3 0.1 3.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 KKK45809.1 - 0.19 11.2 13.2 0.074 12.5 2.9 3.2 3 0 0 3 3 3 0 zinc-ribbon domain CEBP_ZZ PF16366.5 KKK45809.1 - 0.3 11.4 5.4 0.43 10.9 3.6 2.3 1 1 1 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PHD PF00628.29 KKK45809.1 - 0.31 11.0 14.2 0.085 12.8 9.3 2.3 2 0 0 2 2 2 0 PHD-finger TackOD1 PF18551.1 KKK45809.1 - 0.42 10.3 13.3 0.096 12.3 0.5 3.4 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 zf-RING_2 PF13639.6 KKK45809.1 - 0.73 10.2 20.0 4 7.9 11.9 2.9 2 1 0 2 2 2 0 Ring finger domain Zn_ribbon_17 PF17120.5 KKK45809.1 - 0.73 9.5 15.3 0.075 12.7 6.4 2.7 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KKK45809.1 - 0.79 9.8 14.4 0.17 11.9 1.2 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 KKK45809.1 - 0.86 9.5 19.0 0.7 9.8 2.1 3.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_12 PF11331.8 KKK45809.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.9 3 2 1 4 4 3 0 Probable zinc-ribbon domain DUF35_N PF12172.8 KKK45809.1 - 1.8 8.5 5.5 15 5.6 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FANCL_C PF11793.8 KKK45809.1 - 3.3 7.9 10.5 5.3 7.3 6.5 2.8 2 0 0 2 2 2 0 FANCL C-terminal domain IBR PF01485.21 KKK45809.1 - 5.8 7.2 16.8 0.75 10.1 3.4 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Radical_SAM PF04055.21 KKK45810.1 - 8.6e-21 75.0 0.1 8.6e-21 75.0 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 KKK45810.1 - 7.2e-10 39.0 0.1 7.2e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 KKK45810.1 - 1.5e-08 35.0 0.1 1.5e-08 35.0 0.1 1.7 1 1 1 2 2 2 1 4Fe-4S single cluster domain Response_reg PF00072.24 KKK45814.1 - 7.4e-15 55.1 0.0 1.6e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KKK45814.1 - 0.00014 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain FleQ PF06490.11 KKK45814.1 - 0.14 12.6 0.0 0.45 10.9 0.0 1.8 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ HATPase_c PF02518.26 KKK45815.1 - 2.9e-09 37.4 0.0 3.1e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FecR PF04773.13 KKK45815.1 - 0.029 15.0 0.0 0.035 14.7 0.0 1.1 1 0 0 1 1 1 0 FecR protein HEAT_2 PF13646.6 KKK45821.1 - 3.1e-06 27.5 0.0 4.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 HEAT repeats Hormone_1 PF00103.20 KKK45821.1 - 0.04 13.6 0.1 0.042 13.6 0.1 1.0 1 0 0 1 1 1 0 Somatotropin hormone family HEAT PF02985.22 KKK45821.1 - 0.13 12.6 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 HEAT repeat HEAT_EZ PF13513.6 KKK45821.1 - 0.25 11.9 0.0 0.5 10.9 0.0 1.5 1 0 0 1 1 1 0 HEAT-like repeat DUF4233 PF14017.6 KKK45824.1 - 0.014 15.8 1.1 0.016 15.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) MAPEG PF01124.18 KKK45824.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 MAPEG family Robl_LC7 PF03259.17 KKK45825.1 - 4.4e-08 32.8 0.2 5.6e-08 32.5 0.2 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain YfaZ PF07437.11 KKK45825.1 - 0.11 12.1 0.2 0.14 11.8 0.2 1.1 1 0 0 1 1 1 0 YfaZ precursor BsuBI_PstI_RE PF06616.11 KKK45828.1 - 0.028 13.7 0.5 0.073 12.4 0.5 1.8 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain VRR_NUC PF08774.11 KKK45828.1 - 0.13 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 VRR-NUC domain RE_XamI PF09572.10 KKK45828.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease Hjc PF01870.18 KKK45828.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DUF3445 PF11927.8 KKK45829.1 - 0.053 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) AbiJ_NTD5 PF18865.1 KKK45830.1 - 1.3 8.8 6.9 0.76 9.6 0.3 4.0 4 0 0 4 4 4 0 AbiJ N-terminal domain 5 Robl_LC7 PF03259.17 KKK45831.1 - 1.1e-11 44.4 0.0 1.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 KKK45831.1 - 3.5e-06 26.9 0.0 3.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 LRR_4 PF12799.7 KKK45832.1 - 1.4e-39 133.4 47.1 4.6e-10 39.6 4.4 7.1 3 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK45832.1 - 8.4e-27 92.7 40.9 1.6e-09 37.4 9.7 6.5 1 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 KKK45832.1 - 1.9e-15 56.8 17.1 8.7e-08 31.9 1.5 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KKK45832.1 - 1.8e-07 30.6 32.9 0.82 9.9 0.4 9.3 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 KKK45832.1 - 2.6e-05 24.1 36.5 8 7.5 1.6 9.8 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_2 PF07723.13 KKK45832.1 - 4.6 8.1 9.0 61 4.5 0.0 5.4 7 0 0 7 7 7 0 Leucine Rich Repeat ColG_sub PF18496.1 KKK45833.1 - 0.12 12.5 1.0 0.52 10.5 0.3 2.5 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain Y_Y_Y PF07495.13 KKK45835.1 - 0.77 9.8 6.4 0.14 12.1 0.6 2.9 4 0 0 4 4 4 0 Y_Y_Y domain Laminin_G_3 PF13385.6 KKK45836.1 - 0.00016 21.8 3.7 0.00034 20.8 2.7 2.1 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily B3 PF02362.21 KKK45836.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 B3 DNA binding domain DUF5348 PF17295.2 KKK45839.1 - 0.0018 18.2 0.0 1.2 9.1 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF5348) DUF1071 PF06378.11 KKK45844.1 - 0.12 11.9 0.3 0.53 9.9 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1071) Ribosomal_S6e PF01092.19 KKK45845.1 - 5.7e-33 113.6 0.7 7e-33 113.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_L24e PF01246.20 KKK45846.1 - 7.4e-19 67.7 5.5 8e-19 67.6 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 KKK45846.1 - 8.4e-05 22.4 2.3 0.00013 21.8 2.3 1.3 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif DUF2116 PF09889.9 KKK45846.1 - 0.0026 17.7 1.3 0.065 13.2 0.2 2.0 2 0 0 2 2 2 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-FLZ PF04570.14 KKK45846.1 - 0.047 13.2 0.9 0.092 12.2 0.9 1.5 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Ribosomal_L7Ae PF01248.26 KKK45847.1 - 2e-18 65.9 0.1 2.5e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dehydratase_MU PF02288.15 KKK45847.1 - 0.017 15.0 0.1 0.021 14.7 0.1 1.1 1 0 0 1 1 1 0 Dehydratase medium subunit Ribosomal_S28e PF01200.18 KKK45848.1 - 3e-28 97.6 1.7 3.9e-28 97.2 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S28e Gelsolin PF00626.22 KKK45849.1 - 1.5e-14 53.6 0.0 3.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat PP1_inhibitor PF05361.12 KKK45849.1 - 0.11 12.5 3.8 0.16 12.0 3.8 1.2 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor RHH_1 PF01402.21 KKK45850.1 - 2.9e-06 27.0 0.0 4.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family VapB_antitoxin PF09957.9 KKK45850.1 - 0.0093 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB RHH_8 PF17723.1 KKK45850.1 - 0.098 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family RIO1 PF01163.22 KKK45851.1 - 8.1e-11 41.9 0.1 1.3e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KKK45851.1 - 1.5e-10 40.9 1.1 2.2e-10 40.4 1.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KKK45851.1 - 1.7e-09 37.4 0.1 2.3e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KKK45851.1 - 9e-08 31.7 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK45851.1 - 7.2e-05 22.8 0.0 0.0017 18.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK45851.1 - 0.0092 14.8 0.4 0.013 14.4 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M22 PF00814.25 KKK45852.1 - 1.8e-79 267.3 0.0 2.2e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Ribosomal_S27 PF01599.19 KKK45853.1 - 1.6e-19 69.8 2.0 2.1e-19 69.4 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S27a Ribosomal_L37e PF01907.19 KKK45853.1 - 7.2e-05 22.9 2.8 0.00012 22.2 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e Zn_Tnp_IS1595 PF12760.7 KKK45853.1 - 0.0075 16.2 2.5 0.01 15.8 2.5 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-HYPF PF07503.12 KKK45853.1 - 0.0077 16.0 3.6 0.094 12.5 0.3 2.2 2 0 0 2 2 2 1 HypF finger zf_C2H2_10 PF18414.1 KKK45853.1 - 0.017 14.7 4.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger DUF2225 PF09986.9 KKK45853.1 - 0.034 13.9 1.3 0.077 12.7 1.3 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) OrfB_Zn_ribbon PF07282.11 KKK45853.1 - 0.036 14.0 0.7 0.052 13.5 0.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.6 KKK45853.1 - 0.038 14.4 0.7 0.046 14.1 0.7 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar ADK_lid PF05191.14 KKK45853.1 - 0.044 13.8 3.6 3.1 7.8 0.2 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid A2L_zn_ribbon PF08792.10 KKK45853.1 - 0.06 13.1 0.3 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain GFA PF04828.14 KKK45853.1 - 0.064 13.6 1.7 6.5 7.2 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_13 PF09855.9 KKK45853.1 - 0.07 13.3 2.9 0.28 11.4 0.1 2.2 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) TF_Zn_Ribbon PF08271.12 KKK45853.1 - 0.077 12.5 1.7 0.15 11.6 1.7 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding HypA PF01155.19 KKK45853.1 - 0.1 12.6 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1451 PF07295.11 KKK45853.1 - 0.12 12.5 0.4 0.13 12.3 0.4 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-C2H2 PF00096.26 KKK45853.1 - 0.12 12.9 4.8 3.8 8.2 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type FYDLN_acid PF09538.10 KKK45853.1 - 0.83 10.4 3.4 0.45 11.2 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NADH_4Fe-4S PF10589.9 KKK45853.1 - 1.1 9.4 4.0 2.4 8.3 0.1 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region zf-ribbon_3 PF13248.6 KKK45853.1 - 1.9 8.0 6.8 1.3 8.5 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_S24e PF01282.19 KKK45854.1 - 1.2e-17 63.7 0.1 1.7e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e DUF359 PF04019.12 KKK45855.1 - 1e-21 76.9 0.3 2e-21 75.9 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF359) DUF3517 PF12030.8 KKK45855.1 - 0.015 14.3 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Spt4 PF06093.13 KKK45856.1 - 3e-13 49.7 0.1 4.1e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zinc-ribbons_6 PF07191.12 KKK45856.1 - 0.034 14.1 1.8 0.039 13.9 1.8 1.1 1 0 0 1 1 1 0 zinc-ribbons HypA PF01155.19 KKK45856.1 - 0.059 13.4 1.0 0.075 13.1 1.0 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 KKK45856.1 - 0.066 12.8 3.5 0.091 12.3 3.5 1.2 1 0 0 1 1 1 0 RecR protein MCR PF18509.1 KKK45856.1 - 0.12 11.9 0.3 0.12 11.9 0.3 1.7 2 0 0 2 2 2 0 Magnetochrome domain zf-RING_4 PF14570.6 KKK45856.1 - 0.15 11.8 3.7 0.24 11.2 3.7 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PolC_DP2 PF03833.13 KKK45856.1 - 0.19 9.6 0.4 0.17 9.8 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C4H2 PF10146.9 KKK45856.1 - 0.23 11.7 3.7 0.28 11.4 3.7 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein TF_Zn_Ribbon PF08271.12 KKK45856.1 - 0.59 9.7 5.2 0.4 10.2 0.4 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 KKK45856.1 - 0.67 9.5 6.0 0.72 9.3 0.4 2.0 1 1 1 2 2 2 0 zinc-ribbon domain ADK_lid PF05191.14 KKK45856.1 - 1.6 8.8 5.6 76 3.4 5.6 2.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid S1 PF00575.23 KKK45857.1 - 3.1e-13 49.9 0.6 9.2e-13 48.3 0.6 1.9 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 KKK45857.1 - 6e-12 45.8 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DeoC PF01791.9 KKK45858.1 - 8.6e-46 156.5 0.0 1e-45 156.2 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase AP_endonuc_2 PF01261.24 KKK45858.1 - 0.052 13.0 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel YCII PF03795.14 KKK45859.1 - 1.5e-12 47.8 0.0 1.7e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Robl_LC7 PF03259.17 KKK45861.1 - 4.5e-20 71.2 0.2 5.4e-20 71.0 0.2 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF2207 PF09972.9 KKK45861.1 - 0.073 11.8 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DDE_Tnp_1 PF01609.21 KKK45864.1 - 1.4e-06 28.2 2.9 3.5e-05 23.6 2.9 2.6 1 1 0 1 1 1 1 Transposase DDE domain ADH_N PF08240.12 KKK45867.1 - 0.00091 19.1 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Robl_LC7 PF03259.17 KKK45868.1 - 3.2e-06 26.8 0.2 4.2e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain Metallophos_2 PF12850.7 KKK45869.1 - 0.00028 21.1 0.0 0.0003 21.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Arf PF00025.21 KKK45873.1 - 2.1e-17 63.1 0.1 2.8e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK45873.1 - 7e-13 48.9 0.0 1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK45873.1 - 1.3e-10 41.2 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KKK45873.1 - 2.6e-06 27.0 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 KKK45873.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KKK45873.1 - 0.00042 19.9 0.4 0.085 12.4 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KKK45873.1 - 0.00071 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KKK45873.1 - 0.029 14.9 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KKK45873.1 - 0.055 12.9 0.1 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KKK45873.1 - 0.09 11.9 0.7 1.1 8.4 0.1 2.6 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 KKK45873.1 - 0.098 12.4 0.4 0.81 9.4 0.4 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KKK45873.1 - 0.11 12.3 0.0 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein 7TMR-DISM_7TM PF07695.11 KKK45874.1 - 2.2 8.1 35.9 1.1 9.1 8.2 3.0 1 1 1 3 3 3 0 7TM diverse intracellular signalling UPF0154 PF03672.13 KKK45874.1 - 2.2 8.4 5.3 5.2 7.2 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF3180 PF11377.8 KKK45874.1 - 5.3 7.2 6.7 8.5 6.5 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3180) DUF2070 PF09843.9 KKK45875.1 - 5.4e-86 289.1 10.4 6.8e-86 288.8 10.4 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) zinc_ribbon_2 PF13240.6 KKK45876.1 - 1.3e-05 24.7 2.8 2e-05 24.1 2.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK45876.1 - 0.00021 21.3 0.5 0.00034 20.6 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK45876.1 - 0.0013 18.1 3.5 0.0029 17.0 3.5 1.6 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KKK45876.1 - 0.0045 17.7 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 zinc-ribbon family Nudix_N_2 PF14803.6 KKK45876.1 - 0.0054 16.6 0.8 0.63 10.0 0.2 2.3 2 0 0 2 2 2 1 Nudix N-terminal DUF2116 PF09889.9 KKK45876.1 - 0.15 12.1 0.4 0.15 12.1 0.4 4.4 5 1 1 6 6 6 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF35_N PF12172.8 KKK45876.1 - 0.38 10.7 1.2 8.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) NOB1_Zn_bind PF08772.11 KKK45876.1 - 0.44 10.7 2.9 53 4.1 5.2 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 KKK45876.1 - 7.7 6.3 5.5 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PAC2 PF09754.9 KKK45877.1 - 3.6e-20 72.9 0.0 4.5e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 PAC2 family Oxidored_FMN PF00724.20 KKK45878.1 - 2.6e-68 230.8 0.0 3.8e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 KKK45878.1 - 1.2e-34 120.0 1.0 1.1e-28 100.3 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK45878.1 - 1.7e-12 47.7 8.2 2.8e-05 24.6 1.7 4.2 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KKK45878.1 - 3e-11 43.1 6.5 7.3e-07 28.7 0.6 3.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK45878.1 - 1.7e-07 31.3 2.6 1.2e-05 25.4 0.0 3.5 5 0 0 5 5 4 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK45878.1 - 6.2e-07 29.1 1.2 4.7e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KKK45878.1 - 8.1e-06 25.3 2.8 1.3e-05 24.6 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KKK45878.1 - 3.3e-05 23.6 2.9 0.1 12.1 0.0 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase Dus PF01207.17 KKK45878.1 - 6.3e-05 22.2 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) FAD_binding_2 PF00890.24 KKK45878.1 - 6.5e-05 22.2 1.0 6.5e-05 22.2 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KKK45878.1 - 0.00022 20.6 1.5 0.0008 18.7 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KKK45878.1 - 0.00045 19.1 1.6 0.00045 19.1 1.6 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 KKK45878.1 - 0.00069 19.0 2.8 0.001 18.4 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KKK45878.1 - 0.0046 16.1 3.6 0.038 13.1 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Peripla_BP_2 PF01497.18 KKK45878.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Polbeta PF18765.1 KKK45879.1 - 2.8e-05 24.1 0.8 7.8e-05 22.7 0.2 2.1 3 0 0 3 3 3 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK45879.1 - 0.00024 21.3 0.1 0.00076 19.7 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Suv3_N PF18114.1 KKK45879.1 - 0.02 15.0 0.3 0.066 13.3 0.3 1.9 1 0 0 1 1 1 0 Suv3 helical N-terminal domain MFS_1 PF07690.16 KKK45882.1 - 3.8e-40 137.9 39.0 5.8e-38 130.7 23.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KKK45882.1 - 0.00016 20.1 12.9 0.13 10.6 0.3 3.6 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Asp_Glu_race PF01177.22 KKK45883.1 - 5.8e-52 176.7 0.0 6.6e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase RPM2 PF08579.11 KKK45883.1 - 0.0055 17.1 0.8 0.01 16.2 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) HGD-D PF06050.13 KKK45883.1 - 0.021 14.6 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Pep_deformylase PF01327.21 KKK45884.1 - 9.5e-32 109.8 0.0 1.1e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase GST_N PF02798.20 KKK45885.1 - 0.094 13.1 0.1 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PPS_PS PF02006.16 KKK45890.1 - 1.3e-06 28.1 0.2 1.5e-06 27.9 0.2 1.1 1 0 0 1 1 1 1 Phosphopantothenate/pantothenate synthetase RcbX PF02341.15 KKK45890.1 - 0.032 14.5 0.4 0.036 14.3 0.4 1.3 1 1 0 1 1 1 0 RbcX protein Acetyltransf_1 PF00583.25 KKK45891.1 - 9.7e-15 54.8 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK45891.1 - 5.3e-13 49.0 0.1 7.2e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK45891.1 - 8.8e-11 42.1 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KKK45891.1 - 2.8e-06 27.2 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KKK45891.1 - 0.00024 21.3 1.5 0.00033 20.8 1.5 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KKK45891.1 - 0.00046 19.7 3.3 0.00064 19.3 3.0 1.5 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KKK45891.1 - 0.0021 18.1 0.0 0.003 17.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KKK45891.1 - 0.064 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 KKK45891.1 - 0.13 12.0 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ApbA_C PF08546.11 KKK45892.1 - 2e-31 108.8 0.1 3.7e-31 107.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KKK45892.1 - 2.5e-28 98.6 0.0 3.7e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SLIDE PF09111.10 KKK45892.1 - 0.015 15.3 0.8 0.055 13.5 0.1 2.3 2 0 0 2 2 2 0 SLIDE DUF72 PF01904.18 KKK45893.1 - 1.4e-10 41.7 0.0 1.6e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF72 Ephrin_rec_like PF07699.13 KKK45896.1 - 0.019 14.7 2.7 0.019 14.7 2.7 2.1 1 1 1 2 2 2 0 Putative ephrin-receptor like Radical_SAM PF04055.21 KKK45901.1 - 0.064 13.6 2.4 0.26 11.6 1.8 2.4 2 1 0 2 2 2 0 Radical SAM superfamily APOBEC_C PF05240.14 KKK45901.1 - 0.093 12.7 0.6 0.43 10.6 0.1 2.3 3 0 0 3 3 3 0 APOBEC-like C-terminal domain HTH_23 PF13384.6 KKK45902.1 - 0.003 17.3 0.1 0.0069 16.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_45 PF14947.6 KKK45902.1 - 0.0056 16.6 1.9 0.015 15.3 1.9 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.19 KKK45902.1 - 0.01 15.7 0.3 0.025 14.5 0.1 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 KKK45902.1 - 0.019 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix DUF2730 PF10805.8 KKK45902.1 - 0.027 14.6 0.6 0.062 13.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) MarR_2 PF12802.7 KKK45902.1 - 0.039 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF2524 PF10732.9 KKK45902.1 - 0.051 13.9 7.3 0.034 14.5 3.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) HTH_Crp_2 PF13545.6 KKK45902.1 - 0.079 13.0 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 KKK45902.1 - 0.088 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain RPA_C PF08784.11 KKK45902.1 - 0.21 12.2 0.0 0.21 12.2 0.0 2.3 2 1 0 2 2 2 0 Replication protein A C terminal AcylCoA_dehyd_C PF12186.8 KKK45902.1 - 0.26 11.4 3.0 1.3 9.2 0.5 2.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Snapin_Pallidin PF14712.6 KKK45902.1 - 4.7 7.7 10.1 0.83 10.1 2.5 2.9 3 0 0 3 3 3 0 Snapin/Pallidin Sigma70_ner PF04546.13 KKK45903.1 - 0.0021 18.0 0.2 0.0025 17.7 0.2 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region SKA2 PF16740.5 KKK45903.1 - 0.011 15.4 0.4 0.013 15.3 0.4 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 YPEB PF14620.6 KKK45903.1 - 0.027 13.8 0.1 0.029 13.7 0.1 1.0 1 0 0 1 1 1 0 YpeB sporulation MCPsignal PF00015.21 KKK45903.1 - 0.056 13.2 0.3 0.057 13.2 0.3 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CENP-H PF05837.12 KKK45903.1 - 0.1 13.0 0.3 0.11 12.9 0.3 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AAA_lid_10 PF17872.1 KKK45904.1 - 0.098 12.8 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 AAA lid domain HSP9_HSP12 PF04119.12 KKK45904.1 - 0.15 12.5 0.1 0.19 12.2 0.1 1.2 1 0 0 1 1 1 0 Heat shock protein 9/12 TYW3 PF02676.14 KKK45906.1 - 0.0058 16.0 0.0 0.0058 16.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Spuma_A9PTase PF03539.14 KKK45907.1 - 0.069 13.3 1.4 0.073 13.2 1.4 1.0 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) DUF4535 PF15054.6 KKK45907.1 - 0.082 12.7 0.3 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Arc_trans_TRASH PF08394.10 KKK45908.1 - 0.58 10.5 9.5 0.38 11.1 5.8 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain zf-FCS PF06467.14 KKK45908.1 - 1.4 8.9 10.4 4.6 7.3 0.1 3.3 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Phage_integrase PF00589.22 KKK45909.1 - 1.1e-14 54.6 0.4 2.8e-14 53.3 0.1 1.8 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_4 PF13495.6 KKK45909.1 - 4.8e-11 43.0 7.1 1.3e-10 41.6 1.7 3.4 2 1 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain zf-RanBP PF00641.18 KKK45909.1 - 0.00038 19.7 2.4 0.00066 19.0 2.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Phage_int_SAM_1 PF02899.17 KKK45909.1 - 0.00051 20.3 2.9 0.0024 18.2 0.2 3.0 4 0 0 4 4 4 1 Phage integrase, N-terminal SAM-like domain DZR PF12773.7 KKK45909.1 - 0.0015 18.5 1.1 0.0026 17.7 0.3 1.7 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KKK45909.1 - 0.0027 17.4 1.5 0.0027 17.4 1.5 2.3 2 0 0 2 2 2 1 zinc-ribbon domain XAF1_C PF18608.1 KKK45909.1 - 0.021 14.3 0.0 0.075 12.6 0.0 1.9 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain TF_Zn_Ribbon PF08271.12 KKK45909.1 - 0.057 13.0 0.3 0.14 11.7 0.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_15 PF17032.5 KKK45909.1 - 0.18 12.5 2.6 0.88 10.4 2.6 2.3 1 1 0 1 1 1 0 zinc-ribbon family HAD_2 PF13419.6 KKK45909.1 - 0.27 11.3 5.1 0.1 12.6 1.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-ribbon_3 PF13248.6 KKK45909.1 - 3.7 7.1 6.5 2.2 7.8 3.3 2.3 2 1 0 2 2 2 0 zinc-ribbon domain Luciferase_N PF05295.11 KKK45911.1 - 0.016 15.2 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain CAF1 PF04857.20 KKK45911.1 - 0.04 13.1 0.2 0.042 13.0 0.2 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Peptidase_M73 PF12389.8 KKK45911.1 - 0.063 13.1 0.2 0.091 12.6 0.2 1.2 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Spatacsin_C PF14649.6 KKK45913.1 - 0.073 12.2 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus Exonuc_VII_L PF02601.15 KKK45916.1 - 2.6 7.5 4.7 5.1 6.6 4.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit IL4_i_Ig PF18258.1 KKK45917.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain DUF4351 PF14261.6 KKK45917.1 - 0.16 12.0 3.0 0.71 10.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) SSV1_ORF_D-335 PF07935.11 KKK45917.1 - 0.5 10.7 5.8 0.75 10.1 5.6 1.5 1 1 0 1 1 1 0 ORF D-335-like protein Kri1 PF05178.12 KKK45917.1 - 6.2 7.4 10.1 2.7 8.6 3.4 2.2 2 0 0 2 2 2 0 KRI1-like family HTH_WhiA PF02650.14 KKK45918.1 - 0.044 14.1 0.3 0.096 13.0 0.3 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain DUF5553 PF17707.1 KKK45918.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5553) IBR PF01485.21 KKK45918.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain BtpA PF03437.15 KKK45921.1 - 0.037 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 BtpA family zf-C3HC4_3 PF13920.6 KKK45922.1 - 0.024 14.5 0.4 0.041 13.8 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KKK45922.1 - 0.085 12.7 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 HD PF01966.22 KKK45923.1 - 2.6e-12 47.0 2.6 5.3e-12 46.0 2.6 1.5 1 0 0 1 1 1 1 HD domain TraI_2 PF07514.11 KKK45923.1 - 0.0012 17.9 0.6 0.003 16.6 0.0 1.9 2 1 0 2 2 2 1 Putative helicase HDOD PF08668.12 KKK45923.1 - 0.049 13.1 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 HDOD domain HNH PF01844.23 KKK45924.1 - 0.0033 17.6 11.7 0.0077 16.4 11.7 1.6 1 0 0 1 1 1 1 HNH endonuclease Phage_integrase PF00589.22 KKK45925.1 - 1.4e-30 106.4 0.0 1.7e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Phage integrase family RNA_pol_Rpb1_6 PF04992.14 KKK45925.1 - 0.029 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 TF_Zn_Ribbon PF08271.12 KKK45926.1 - 0.026 14.0 0.8 0.059 12.9 0.8 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF3185 PF11381.8 KKK45929.1 - 0.5 10.4 5.1 0.47 10.5 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) TauE PF01925.19 KKK45931.1 - 1.6e-30 106.5 16.1 1.8e-30 106.4 16.1 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3487 PF11990.8 KKK45931.1 - 0.13 12.2 12.4 0.36 10.7 0.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3487) Phage_holin_3_6 PF07332.11 KKK45931.1 - 4.5 7.4 14.8 2.7 8.1 0.1 3.0 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MazE_antitoxin PF04014.18 KKK45933.1 - 0.015 15.2 0.1 0.044 13.7 0.0 1.9 1 1 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Zn_dep_PLPC PF00882.18 KKK45935.1 - 3.9e-10 40.0 3.1 4e-09 36.7 0.2 2.2 1 1 1 2 2 2 2 Zinc dependent phospholipase C YdjM PF04307.14 KKK45935.1 - 0.069 12.5 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase UbiA PF01040.18 KKK45936.1 - 1.5e-09 37.5 21.6 2.5e-09 36.8 20.5 1.8 1 1 1 2 2 2 2 UbiA prenyltransferase family Orf78 PF06024.12 KKK45936.1 - 5.7 7.3 11.3 6.4 7.1 0.4 2.9 3 0 0 3 3 3 0 Orf78 (ac78) AAA_5 PF07728.14 KKK45937.1 - 1.8e-22 79.8 0.0 3.3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KKK45937.1 - 4.9e-11 43.2 0.0 1.3e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 KKK45937.1 - 2.4e-07 30.7 0.0 6e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KKK45937.1 - 3.2e-06 27.7 0.0 7.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbbQ_C PF08406.10 KKK45937.1 - 4.3e-05 23.7 0.0 7.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA_22 PF13401.6 KKK45937.1 - 0.00013 22.3 0.0 0.00085 19.6 0.0 2.4 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KKK45937.1 - 0.00033 21.0 0.0 0.001 19.5 0.0 2.0 1 1 0 1 1 1 1 RNA helicase PPV_E1_C PF00519.17 KKK45937.1 - 0.0051 15.7 0.1 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 Papillomavirus helicase RuvB_N PF05496.12 KKK45937.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KKK45937.1 - 0.011 15.4 0.0 0.029 14.1 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 KKK45937.1 - 0.012 15.4 0.2 0.066 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK45937.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRR_10 PF18805.1 KKK45937.1 - 0.013 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat PhoH PF02562.16 KKK45937.1 - 0.013 14.9 0.2 0.23 10.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 KKK45937.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK45937.1 - 0.02 15.1 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 KKK45937.1 - 0.021 15.1 0.9 0.027 14.7 0.0 1.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 KKK45937.1 - 0.049 14.2 0.1 0.2 12.2 0.0 2.2 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KKK45937.1 - 0.094 12.4 0.0 0.75 9.5 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KKK45937.1 - 0.1 12.7 0.1 0.86 9.7 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain VWA PF00092.28 KKK45938.1 - 0.00016 22.0 0.2 0.009 16.3 0.1 3.0 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KKK45938.1 - 0.0011 19.6 0.1 0.0047 17.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain CobT_C PF11775.8 KKK45938.1 - 0.012 15.3 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain VWA_CoxE PF05762.14 KKK45938.1 - 0.096 12.1 0.0 0.3 10.4 0.0 1.8 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Dpoe2NT PF12213.8 KKK45938.1 - 0.31 11.3 2.6 3.9 7.8 1.2 3.2 3 0 0 3 3 3 0 DNA polymerases epsilon N terminal Radical_SAM PF04055.21 KKK45939.1 - 1.5e-19 71.0 2.2 2.3e-19 70.4 0.0 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK45939.1 - 0.029 14.6 0.1 0.029 14.6 0.1 2.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fe_dep_repr_C PF02742.15 KKK45939.1 - 0.079 13.1 0.3 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain TIR_2 PF13676.6 KKK45940.1 - 8.7e-14 52.1 0.2 1.9e-13 51.1 0.2 1.5 1 0 0 1 1 1 1 TIR domain NosD PF05048.13 KKK45940.1 - 1.7e-13 50.4 35.0 1.7e-13 50.4 35.0 2.0 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK45940.1 - 1.6e-09 37.8 44.0 1.6e-09 37.8 44.0 2.3 2 0 0 2 2 2 1 Right handed beta helix region PCI PF01399.27 KKK45940.1 - 0.54 10.8 7.3 1.1 9.8 4.5 2.8 2 1 0 2 2 2 0 PCI domain Peptidase_C25 PF01364.18 KKK45944.1 - 1.9e-57 195.2 3.0 2.2e-57 195.0 3.0 1.0 1 0 0 1 1 1 1 Peptidase family C25 zinc_ribbon_2 PF13240.6 KKK45945.1 - 0.016 14.9 0.2 0.03 14.0 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF3797 PF12677.7 KKK45945.1 - 0.081 12.8 0.6 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-ribbon_3 PF13248.6 KKK45945.1 - 0.12 11.8 0.1 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KKK45945.1 - 0.16 12.0 2.2 1.6 8.9 2.2 2.3 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_2 PF13240.6 KKK45950.1 - 7.3e-07 28.7 2.4 0.0026 17.4 0.2 2.3 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.7 KKK45950.1 - 1.7e-05 24.8 0.6 3.9e-05 23.6 0.6 1.6 1 1 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KKK45950.1 - 0.0025 17.1 1.9 0.0076 15.6 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-C2H2_11 PF16622.5 KKK45950.1 - 0.0031 17.2 2.1 0.66 9.8 0.1 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 KKK45950.1 - 0.0096 16.2 1.3 5 7.5 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon Elf1 PF05129.13 KKK45950.1 - 0.025 14.6 0.2 0.034 14.2 0.2 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-dskA_traR PF01258.17 KKK45950.1 - 0.029 14.3 1.1 0.19 11.7 1.1 2.1 1 1 1 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Nudix_N_2 PF14803.6 KKK45950.1 - 0.036 14.0 1.9 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 KKK45950.1 - 0.042 14.0 0.6 0.078 13.1 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain ROS_MUCR PF05443.11 KKK45950.1 - 0.071 13.2 0.2 0.3 11.2 0.0 1.8 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein Prim_Zn_Ribbon PF08273.12 KKK45950.1 - 0.11 12.8 1.2 1.4 9.3 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Ephrin_rec_like PF07699.13 KKK45950.1 - 0.2 11.5 2.2 2.9 7.7 0.1 2.6 1 1 1 2 2 2 0 Putative ephrin-receptor like TF_Zn_Ribbon PF08271.12 KKK45950.1 - 0.43 10.1 2.8 1.1 8.9 2.8 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding UPF0547 PF10571.9 KKK45950.1 - 0.47 10.6 0.2 0.47 10.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Acetyltransf_1 PF00583.25 KKK45951.1 - 5.8e-13 49.1 0.2 2.4e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK45951.1 - 3.1e-07 30.4 0.1 9.3e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK45951.1 - 3.6e-05 24.5 0.0 6.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK45951.1 - 0.00025 21.4 0.0 0.00056 20.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK45951.1 - 0.0026 17.9 0.1 0.0041 17.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 3-dmu-9_3-mt PF06983.13 KKK45951.1 - 0.026 15.1 0.5 0.066 13.7 0.1 1.8 2 0 0 2 2 2 0 3-demethylubiquinone-9 3-methyltransferase Cas_Cas1 PF01867.16 KKK45951.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas1 Acetyltransf_CG PF14542.6 KKK45951.1 - 0.081 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CPBP PF02517.16 KKK45952.1 - 4.7e-10 39.7 15.0 4.7e-10 39.7 15.0 2.1 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease PAS_9 PF13426.7 KKK45954.1 - 5.5e-19 68.4 3.2 3.1e-15 56.3 0.1 2.7 1 1 1 2 2 2 2 PAS domain HATPase_c PF02518.26 KKK45954.1 - 1.9e-15 57.4 0.9 3.7e-15 56.4 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 KKK45954.1 - 8.5e-15 54.7 0.0 3.6e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 KKK45954.1 - 2.8e-11 43.6 0.0 1.1e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KKK45954.1 - 3.8e-06 26.8 0.0 0.027 14.5 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 KKK45954.1 - 0.0042 17.3 0.0 0.14 12.4 0.0 2.6 2 1 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 KKK45954.1 - 0.03 14.2 1.4 0.15 12.0 1.4 2.3 1 1 0 1 1 1 0 GHKL domain HATPase_c_2 PF13581.6 KKK45954.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 KKK45955.1 - 1.6e-18 66.9 0.2 1.8e-18 66.7 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain UPF0160 PF03690.13 KKK45955.1 - 0.015 14.9 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) PIN_4 PF13638.6 KKK45955.1 - 0.039 14.2 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 PIN domain PAS_9 PF13426.7 KKK45956.1 - 3.3e-14 53.0 5.1 1.4e-10 41.4 0.1 4.4 4 0 0 4 4 4 2 PAS domain HATPase_c PF02518.26 KKK45956.1 - 1.6e-13 51.1 0.3 8e-13 48.9 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KKK45956.1 - 1e-10 41.4 0.0 6.6e-06 26.0 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KKK45956.1 - 1.8e-10 40.8 0.0 3.6e-09 36.6 0.0 2.8 3 0 0 3 3 3 1 PAS fold GAF_2 PF13185.6 KKK45956.1 - 4.8e-07 30.1 0.0 7.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 GAF domain PAS_4 PF08448.10 KKK45956.1 - 9.6e-07 29.0 0.0 0.00017 21.8 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 KKK45956.1 - 5.4e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 KKK45956.1 - 9.3e-05 23.1 0.0 0.00015 22.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KKK45956.1 - 0.00034 20.6 0.2 0.00093 19.2 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 KKK45956.1 - 0.0008 19.3 1.2 0.0008 19.3 1.2 2.6 3 0 0 3 3 3 1 GHKL domain PAS_10 PF13596.6 KKK45956.1 - 0.018 15.6 0.3 17 6.0 0.0 3.5 3 0 0 3 3 3 0 PAS domain GAF_3 PF13492.6 KKK45956.1 - 0.027 14.8 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 GAF domain PAS_7 PF12860.7 KKK45956.1 - 0.091 12.9 0.0 0.63 10.2 0.0 2.4 2 0 0 2 2 2 0 PAS fold Arf PF00025.21 KKK45957.1 - 1.3e-17 63.8 0.1 2.1e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK45957.1 - 2.3e-13 50.4 0.1 9e-13 48.5 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK45957.1 - 4e-12 46.0 0.0 7.4e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KKK45957.1 - 1.2e-05 25.3 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KKK45957.1 - 0.00089 19.0 0.1 0.0022 17.8 0.1 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 KKK45957.1 - 0.0045 16.9 0.2 0.32 10.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KKK45957.1 - 0.005 17.4 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KKK45957.1 - 0.0086 16.6 0.6 0.013 16.0 0.5 1.5 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.12 KKK45957.1 - 0.027 13.8 0.0 0.054 12.9 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TPR_2 PF07719.17 KKK45957.1 - 0.03 14.4 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK45957.1 - 0.033 14.0 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KKK45957.1 - 0.082 13.2 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_16 PF13191.6 KKK45957.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 KKK45958.1 - 5.4e-22 78.3 0.8 7.6e-22 77.8 0.8 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK45958.1 - 1.1e-05 25.4 0.0 2.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK45958.1 - 0.0075 15.8 0.0 0.019 14.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 KKK45958.1 - 0.043 13.5 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KKK45958.1 - 0.046 14.1 1.7 0.38 11.2 0.3 2.7 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C3HC4_3 PF13920.6 KKK45959.1 - 0.0079 16.0 2.3 0.012 15.4 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) 4HB_MCP_1 PF12729.7 KKK45959.1 - 0.028 13.9 0.2 0.028 13.9 0.2 2.6 3 1 0 3 3 3 0 Four helix bundle sensory module for signal transduction PatG_D PF18047.1 KKK45959.1 - 0.04 14.3 0.0 0.64 10.5 0.0 2.4 2 0 0 2 2 2 0 PatG Domain FTO_CTD PF12934.7 KKK45960.1 - 0.11 12.3 0.2 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 FTO C-terminal domain Gtr1_RagA PF04670.12 KKK45961.1 - 2.1e-22 79.6 1.6 3e-22 79.1 1.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK45961.1 - 4e-07 30.1 0.0 1.2e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KKK45961.1 - 0.0041 16.7 0.0 0.016 14.8 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 KKK45961.1 - 0.081 13.1 0.1 0.36 11.1 0.1 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 KKK45961.1 - 0.32 11.4 3.8 0.85 10.1 0.3 3.0 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 KKK45962.1 - 7.2e-19 67.9 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KKK45962.1 - 1.8e-13 50.8 0.0 3.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK45962.1 - 1.4e-12 47.5 0.0 2.3e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KKK45962.1 - 9.8e-06 25.6 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KKK45962.1 - 0.0019 17.6 0.2 0.0093 15.3 0.1 2.2 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KKK45962.1 - 0.013 15.5 0.2 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KKK45962.1 - 0.022 15.3 0.3 0.042 14.4 0.3 1.8 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KKK45962.1 - 0.038 14.5 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KKK45962.1 - 0.046 14.0 0.9 0.14 12.5 0.3 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KKK45962.1 - 0.13 12.7 0.0 0.38 11.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain GAF_2 PF13185.6 KKK45963.1 - 2.6e-07 31.0 0.0 3.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 KKK45963.1 - 1.9e-06 28.2 0.0 3.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 GAF domain PAS_9 PF13426.7 KKK45963.1 - 1.4e-05 25.3 1.0 0.2 11.9 0.2 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 KKK45963.1 - 4.9e-05 23.3 0.0 0.0027 17.7 0.0 2.5 2 0 0 2 2 2 1 PAS fold GAF PF01590.26 KKK45963.1 - 0.0025 18.5 0.0 0.0037 17.9 0.0 1.3 1 0 0 1 1 1 1 GAF domain PAS_4 PF08448.10 KKK45963.1 - 0.004 17.4 0.0 0.059 13.6 0.0 2.3 2 0 0 2 2 2 1 PAS fold Transglut_core PF01841.19 KKK45964.1 - 2.6e-16 60.1 0.0 3e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Transglutaminase-like superfamily Transglut_core2 PF13369.6 KKK45964.1 - 0.0016 18.1 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily PHO4 PF01384.20 KKK45966.1 - 1.9e-21 76.5 9.2 1.9e-21 76.5 9.2 1.8 1 1 1 2 2 2 2 Phosphate transporter family DUF2583 PF10762.9 KKK45966.1 - 6.2 7.3 9.6 4.1 7.9 4.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) PhoU_div PF01865.16 KKK45967.1 - 3.4e-07 29.8 11.2 4.1e-07 29.5 11.2 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF47 LepA_C PF06421.12 KKK45967.1 - 0.017 15.3 1.5 0.017 15.3 1.5 2.0 2 2 0 2 2 2 0 GTP-binding protein LepA C-terminus Fib_alpha PF08702.10 KKK45967.1 - 2.7 8.2 6.6 2.9 8.1 0.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ECH_1 PF00378.20 KKK45968.1 - 2.6e-43 148.2 0.0 8.5e-43 146.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK45968.1 - 2e-36 126.1 0.0 7.2e-31 107.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase COX5A PF02284.16 KKK45969.1 - 0.11 12.5 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Acatn PF13000.7 KKK45970.1 - 2.3e-07 29.7 7.8 2.7e-07 29.5 7.8 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 BT1 PF03092.16 KKK45970.1 - 4.6e-06 25.1 0.2 5.4e-06 24.9 0.2 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 KKK45970.1 - 6.4e-06 25.3 2.7 7.2e-06 25.2 2.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KKK45970.1 - 1.2e-05 24.1 3.9 1.3e-05 23.9 3.9 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein LacY_symp PF01306.19 KKK45970.1 - 0.0016 17.3 1.9 0.0019 17.1 1.9 1.0 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_1 PF07690.16 KKK45971.1 - 3.4e-12 46.0 11.9 3.9e-12 45.8 11.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.16 KKK45971.1 - 0.0011 17.3 5.4 0.13 10.4 1.3 2.0 2 0 0 2 2 2 2 BT1 family Sugar_tr PF00083.24 KKK45971.1 - 0.0039 16.1 6.5 0.0039 16.1 6.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter L_HMGIC_fpl PF10242.9 KKK45971.1 - 1.2 9.3 7.8 4.8 7.3 8.0 1.8 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein DUF2070 PF09843.9 KKK45971.1 - 5.2 5.2 11.4 6.9 4.8 11.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5090 PF17009.5 KKK45971.1 - 7.5 6.5 10.3 11 5.9 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Peroxin-13_N PF04088.13 KKK45971.1 - 10 6.4 8.5 0.71 10.1 2.9 2.0 2 1 0 2 2 2 0 Peroxin 13, N-terminal region Aminotran_1_2 PF00155.21 KKK45972.1 - 1.9e-59 201.7 0.0 2.2e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KKK45972.1 - 0.0028 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V WD40 PF00400.32 KKK45974.1 - 7.1e-10 39.3 7.0 0.37 11.7 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KKK45974.1 - 5.5e-09 36.2 0.0 0.21 11.9 0.0 5.3 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KKK45974.1 - 2.1e-08 34.0 0.0 1.3e-05 24.9 0.0 2.6 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 KKK45974.1 - 1.2e-06 28.9 0.4 1.5 9.4 0.0 5.7 6 0 0 6 6 6 1 PQQ-like domain Lactonase PF10282.9 KKK45974.1 - 0.00036 19.9 0.9 0.61 9.3 0.1 3.9 1 1 3 4 4 4 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KKK45974.1 - 0.004 15.7 0.7 1.4 7.4 0.0 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ PF01011.21 KKK45974.1 - 0.013 15.3 4.3 21 5.2 0.0 5.7 6 0 0 6 6 6 0 PQQ enzyme repeat DUF3997 PF13162.6 KKK45974.1 - 0.04 14.2 2.3 0.57 10.5 0.2 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3997) Tox-SGS PF15651.6 KKK45974.1 - 0.046 14.0 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Salivary glad secreted protein domain toxin Colicin_E5 PF12106.8 KKK45974.1 - 0.048 14.0 8.2 1.6 9.1 0.1 4.8 5 2 1 6 6 6 0 Colicin E5 ribonuclease domain WD40_like PF17005.5 KKK45974.1 - 0.078 12.3 11.0 0.6 9.4 3.2 4.7 2 1 1 4 4 4 0 WD40-like domain PD40 PF07676.12 KKK45974.1 - 0.41 10.7 8.8 13 5.9 0.3 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Glyco_hydro_4 PF02056.16 KKK45975.1 - 5.1e-43 146.8 0.0 1.7e-42 145.1 0.0 1.8 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase Glyco_hydro_4C PF11975.8 KKK45975.1 - 5.3e-42 144.3 0.0 7.2e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain Ldh_1_N PF00056.23 KKK45975.1 - 0.00097 19.3 0.3 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 lactate/malate dehydrogenase, NAD binding domain TM1586_NiRdase PF14512.6 KKK45978.1 - 0.00091 18.9 0.0 0.00091 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 KKK45978.1 - 0.068 13.2 0.0 0.097 12.7 0.0 1.3 1 1 0 1 1 1 0 Nitroreductase family MTS PF05175.14 KKK45979.1 - 8.7e-31 106.7 0.0 1.4e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KKK45979.1 - 0.00016 21.5 0.1 0.00029 20.6 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 KKK45979.1 - 0.00055 19.5 0.2 0.0027 17.3 0.0 2.1 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 KKK45979.1 - 0.0044 16.8 0.0 0.0087 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK45979.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KKK45979.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase NRDD PF13597.6 KKK45980.1 - 4.1e-15 55.6 0.3 2.8e-12 46.2 1.1 2.5 2 1 0 2 2 2 2 Anaerobic ribonucleoside-triphosphate reductase HTH_45 PF14947.6 KKK45980.1 - 0.00034 20.5 1.2 0.00034 20.5 1.2 2.8 3 0 0 3 3 3 1 Winged helix-turn-helix HTH_20 PF12840.7 KKK45980.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain OTCace_N PF02729.21 KKK45981.1 - 5e-46 156.4 0.0 8e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KKK45981.1 - 7.3e-25 87.9 0.0 1e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Ribosomal_L44 PF00935.19 KKK45982.1 - 4.5e-23 81.5 9.3 4.5e-23 81.5 9.3 1.3 2 0 0 2 2 2 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 KKK45982.1 - 0.03 14.8 4.1 0.03 14.8 4.1 3.2 2 2 1 3 3 3 0 Ribosomal protein L33 Zn_Tnp_IS1595 PF12760.7 KKK45982.1 - 0.052 13.5 1.4 1.8 8.6 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK45982.1 - 0.19 11.2 2.7 7.9 6.0 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Haem_bd PF14376.6 KKK45982.1 - 0.73 9.8 5.4 1.2 9.1 5.4 1.5 1 1 0 1 1 1 0 Haem-binding domain NOB1_Zn_bind PF08772.11 KKK45982.1 - 0.76 10.0 7.4 0.27 11.4 2.9 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Elf1 PF05129.13 KKK45982.1 - 2.3 8.4 8.6 2.9 8.0 0.5 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF5001 PF16392.5 KKK45985.1 - 0.027 14.3 6.3 0.29 11.1 0.4 3.5 3 1 1 4 4 4 0 Ig-like domain Peptidase_M20 PF01546.28 KKK45986.1 - 1.6e-32 112.9 0.0 2.4e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KKK45986.1 - 6.7e-21 74.3 0.0 2e-20 72.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KKK45986.1 - 6.6e-05 22.7 0.0 0.00037 20.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 partial_CstF PF15861.5 KKK45986.1 - 0.062 13.1 0.2 0.21 11.4 0.2 1.9 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain DUF2870 PF11069.8 KKK45986.1 - 0.074 13.4 0.3 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) VWA_2 PF13519.6 KKK45987.1 - 2.8e-13 50.4 0.1 5.3e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KKK45987.1 - 7.6e-10 39.3 0.1 1.1e-09 38.8 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KKK45987.1 - 3.1e-09 36.9 0.2 4.8e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Ssl1-like C1_1 PF00130.22 KKK45987.1 - 5.8e-06 26.1 18.2 5.9e-05 22.9 6.4 3.1 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KKK45987.1 - 3.3e-05 23.7 21.1 0.0028 17.5 5.3 2.6 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.6 KKK45987.1 - 0.0027 17.6 6.3 0.0027 17.6 6.3 3.5 2 2 1 3 3 3 1 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 KKK45987.1 - 0.011 15.7 6.1 0.011 15.7 6.1 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 KKK45987.1 - 0.017 15.4 19.5 0.046 14.0 4.0 3.9 4 0 0 4 4 4 0 C1 domain zf-RING_2 PF13639.6 KKK45987.1 - 0.027 14.8 21.2 0.55 10.6 6.8 2.6 2 1 0 2 2 2 0 Ring finger domain Cytochrome_CBB3 PF13442.6 KKK45987.1 - 0.16 12.3 2.9 1.5 9.2 0.6 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Zn_ribbon_17 PF17120.5 KKK45987.1 - 0.59 9.8 19.1 0.39 10.4 4.3 3.2 2 2 0 2 2 2 0 Zinc-ribbon, C4HC2 type tRNA-synt_1g PF09334.11 KKK45988.1 - 5.2e-116 387.6 0.0 5.9e-116 387.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKK45988.1 - 2e-13 49.5 0.1 3.2e-09 35.6 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Laminin_EGF PF00053.24 KKK45988.1 - 0.028 14.6 2.1 0.05 13.7 2.1 1.4 1 0 0 1 1 1 0 Laminin EGF domain DB_JBP1 PF18526.1 KKK45988.1 - 0.088 12.8 0.2 6.5 6.7 0.1 2.3 2 0 0 2 2 2 0 Thymine dioxygenase JBP1 DNA-binding domain DZR PF12773.7 KKK45988.1 - 0.33 11.0 5.3 0.79 9.8 5.0 1.8 1 1 1 2 2 2 0 Double zinc ribbon AAA_31 PF13614.6 KKK45993.1 - 1.3e-19 70.9 0.0 1.4e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KKK45993.1 - 1.3e-15 57.6 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KKK45993.1 - 5.9e-10 38.8 0.0 6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KKK45993.1 - 5.8e-07 29.2 0.0 6.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 KKK45993.1 - 1.2e-06 28.2 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KKK45993.1 - 1.1e-05 25.0 0.0 1.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 KKK45993.1 - 8.5e-05 22.0 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 KKK45993.1 - 0.00012 22.0 0.1 0.00035 20.4 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MipZ PF09140.11 KKK45993.1 - 0.00021 20.7 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ SRP54 PF00448.22 KKK45993.1 - 0.0017 18.0 0.0 0.0017 18.0 0.0 1.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 KKK45993.1 - 0.018 14.9 0.1 0.05 13.4 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 KKK45993.1 - 0.038 13.0 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CTP_synth_N PF06418.14 KKK45993.1 - 0.041 13.2 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 CTP synthase N-terminus ResIII PF04851.15 KKK45993.1 - 0.06 13.3 0.0 0.078 13.0 0.0 1.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KKK45993.1 - 0.071 13.1 0.0 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KKK45993.1 - 0.072 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KKK45993.1 - 0.077 13.4 0.2 0.27 11.7 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KKK45993.1 - 0.088 13.1 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain Polbeta PF18765.1 KKK45998.1 - 1.4e-08 34.7 0.6 3.1e-08 33.6 0.4 1.8 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK45998.1 - 6.8e-07 29.5 0.4 1.2e-06 28.6 0.4 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain SMODS PF18144.1 KKK45998.1 - 0.00041 20.6 0.0 0.001 19.2 0.0 1.6 2 0 0 2 2 2 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain JLPA PF16668.5 KKK45998.1 - 0.0096 15.0 1.1 0.014 14.5 1.1 1.2 1 1 0 1 1 1 1 Adhesin from Campylobacter NTF-like PF14540.6 KKK45998.1 - 0.0098 15.7 0.1 0.018 14.8 0.1 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase-like ABC_tran_CTD PF16326.5 KKK46000.1 - 0.01 16.1 8.4 0.96 9.7 1.4 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain FapA PF03961.13 KKK46000.1 - 0.018 13.7 0.2 0.018 13.7 0.2 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Spc42p PF11544.8 KKK46000.1 - 0.023 14.7 0.2 0.023 14.7 0.2 3.1 2 1 1 3 3 3 0 Spindle pole body component Spc42p DUF16 PF01519.16 KKK46000.1 - 0.026 15.0 5.2 0.046 14.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 FliJ PF02050.16 KKK46000.1 - 0.049 13.9 2.5 0.48 10.6 0.8 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Laminin_G_1 PF00054.23 KKK46000.1 - 0.058 13.6 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain AAA_23 PF13476.6 KKK46000.1 - 0.065 13.7 6.5 0.092 13.2 6.0 1.5 1 1 0 1 1 1 0 AAA domain DoxD PF04173.13 KKK46000.1 - 0.094 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 TQO small subunit DoxD FlgN PF05130.12 KKK46000.1 - 0.16 12.5 5.0 0.22 12.0 0.7 2.3 2 1 0 2 2 2 0 FlgN protein Shugoshin_N PF07558.11 KKK46000.1 - 0.16 11.9 0.3 0.16 11.9 0.3 2.8 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF2203 PF09969.9 KKK46000.1 - 0.16 12.7 2.5 0.89 10.3 0.3 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CENP-F_leu_zip PF10473.9 KKK46000.1 - 0.2 11.7 7.1 0.29 11.1 0.6 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP PF04728.13 KKK46000.1 - 0.26 11.7 0.4 0.26 11.7 0.4 3.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF2508 PF10704.9 KKK46000.1 - 0.37 11.0 6.2 2.8 8.2 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) DASH_Spc34 PF08657.10 KKK46000.1 - 0.42 10.4 5.7 0.96 9.2 0.5 2.0 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF2443 PF10398.9 KKK46000.1 - 0.42 10.7 4.2 7 6.8 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) DUF948 PF06103.11 KKK46000.1 - 0.61 10.4 2.8 3.2 8.1 0.7 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 KKK46000.1 - 0.66 9.8 8.4 1.4 8.7 1.0 2.8 2 1 1 3 3 3 0 Septum formation initiator Prefoldin PF02996.17 KKK46000.1 - 1.2 9.0 7.3 2.4 8.1 0.5 2.9 2 1 1 3 3 3 0 Prefoldin subunit YabA PF06156.13 KKK46000.1 - 2 9.1 6.3 5 7.8 4.0 2.5 2 1 0 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 KKK46000.1 - 4.9 7.3 6.8 1.3 9.2 2.7 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Beta-lactamase PF00144.24 KKK46001.1 - 2.2e-64 217.8 0.0 1.8e-52 178.6 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase Alkyl_sulf_C PF14864.6 KKK46001.1 - 0.045 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal tRNA_edit PF04073.15 KKK46002.1 - 3.8e-27 94.8 0.0 4.5e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain PRORP PF16953.5 KKK46002.1 - 0.17 11.4 0.0 0.23 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P HATPase_c PF02518.26 KKK46003.1 - 9e-23 80.9 1.8 1.2e-22 80.5 0.8 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 KKK46003.1 - 3e-12 47.0 0.0 6.8e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KKK46003.1 - 1.2e-11 44.5 0.1 2.6e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 KKK46003.1 - 1.2e-05 26.0 0.0 0.0001 22.9 0.0 2.2 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 KKK46003.1 - 0.008 16.0 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 KKK46003.1 - 0.03 14.7 0.0 0.56 10.5 0.0 2.6 2 1 0 2 2 2 0 GAF domain HATPase_c_2 PF13581.6 KKK46003.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Fer4_2 PF12797.7 KKK46004.1 - 5.1e-10 38.8 25.0 2.3e-05 24.2 2.6 3.7 4 0 0 4 4 3 3 4Fe-4S binding domain Fer4_6 PF12837.7 KKK46004.1 - 9.6e-10 38.1 22.9 5.9e-05 23.0 1.6 3.9 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 KKK46004.1 - 1.6e-09 37.8 17.1 4e-05 23.6 0.4 3.7 3 1 2 5 5 5 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46004.1 - 4.2e-09 36.4 17.5 3.5e-07 30.2 9.5 3.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46004.1 - 6.9e-08 32.0 27.2 1.2e-05 24.9 2.5 3.8 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK46004.1 - 9.3e-08 32.6 19.6 5.4e-06 26.9 10.0 3.0 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK46004.1 - 2.3e-07 31.4 9.3 0.034 14.9 0.2 3.6 3 1 0 3 3 3 3 4Fe-4S single cluster domain Fer4_9 PF13187.6 KKK46004.1 - 2.7e-06 27.4 20.0 3e-05 24.1 9.7 2.8 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK46004.1 - 1.2e-05 25.6 16.1 3.3e-05 24.3 8.1 2.9 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46004.1 - 3.3e-05 24.3 13.4 3.5e-05 24.3 5.5 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK46004.1 - 0.00013 22.2 9.1 0.0037 17.6 2.3 3.7 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_18 PF13746.6 KKK46004.1 - 0.003 17.8 15.7 0.0049 17.0 0.9 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK46004.1 - 0.0041 17.9 14.0 0.033 15.0 0.2 3.3 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 KKK46004.1 - 0.0044 17.5 19.3 0.082 13.5 2.1 3.7 4 0 0 4 4 4 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_16 PF13484.6 KKK46004.1 - 0.013 16.4 10.3 0.013 16.4 10.3 3.4 2 2 2 4 4 4 0 4Fe-4S double cluster binding domain PAS PF00989.25 KKK46005.1 - 2.1e-26 92.2 0.3 1.8e-11 44.0 0.0 4.6 4 0 0 4 4 4 3 PAS fold PAS_9 PF13426.7 KKK46005.1 - 1.5e-25 89.4 11.5 3.9e-09 36.7 0.1 4.7 4 0 0 4 4 4 3 PAS domain HATPase_c PF02518.26 KKK46005.1 - 4.1e-25 88.5 0.4 1.5e-24 86.7 0.1 2.1 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KKK46005.1 - 2.4e-19 69.4 0.2 1e-11 44.9 0.0 4.2 4 1 0 4 4 3 3 PAS fold PAS_4 PF08448.10 KKK46005.1 - 2.4e-15 56.8 0.0 0.0011 19.2 0.0 4.4 4 0 0 4 4 4 3 PAS fold HisKA PF00512.25 KKK46005.1 - 5.3e-10 39.2 0.3 1.5e-09 37.7 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 KKK46005.1 - 1.9e-09 37.3 0.3 0.033 14.2 0.0 4.5 4 0 0 4 4 4 2 PAS domain PAS_11 PF14598.6 KKK46005.1 - 0.0024 18.0 0.0 0.037 14.1 0.0 2.9 3 1 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 KKK46005.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK46005.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PhosphMutase PF10143.9 KKK46005.1 - 0.017 15.0 0.3 0.37 10.7 0.0 2.9 3 0 0 3 3 3 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase PAS_10 PF13596.6 KKK46005.1 - 0.028 15.0 0.4 2.9 8.5 0.0 3.5 3 0 0 3 3 3 0 PAS domain Bax1-I PF01027.20 KKK46005.1 - 0.066 13.0 2.8 0.1 12.4 2.8 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 RAG1_imp_bd PF12560.8 KKK46005.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 RAG1 importin binding Frizzled PF01534.17 KKK46005.1 - 0.21 10.6 1.8 0.34 9.9 1.8 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Claudin_3 PF06653.11 KKK46005.1 - 0.42 10.5 4.9 0.86 9.5 4.9 1.5 1 0 0 1 1 1 0 Tight junction protein, Claudin-like PIN PF01850.21 KKK46006.1 - 1.3e-05 25.7 0.3 1.3e-05 25.6 0.3 1.1 1 0 0 1 1 1 1 PIN domain ADH_zinc_N PF00107.26 KKK46007.1 - 1.2e-27 96.5 0.0 2.2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KKK46007.1 - 3.5e-16 59.0 0.8 6.9e-16 58.1 0.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KKK46007.1 - 1e-10 41.5 0.1 1.8e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KKK46007.1 - 0.00016 22.7 0.0 0.00023 22.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KKK46007.1 - 0.00088 18.6 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KKK46007.1 - 0.0057 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L21e PF01157.18 KKK46007.1 - 0.079 12.8 0.0 3.3 7.6 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein L21e CcmF_C PF16327.5 KKK46008.1 - 0.0006 19.2 3.3 0.0026 17.1 0.1 2.1 1 1 1 2 2 2 1 Cytochrome c-type biogenesis protein CcmF C-terminal HisKA_7TM PF16927.5 KKK46008.1 - 0.027 14.5 23.3 0.12 12.4 7.0 2.1 1 1 1 2 2 2 0 N-terminal 7TM region of histidine kinase Acyl_transf_3 PF01757.22 KKK46008.1 - 0.47 9.5 19.4 4.7 6.2 19.4 2.0 1 1 0 1 1 1 0 Acyltransferase family OppC_N PF12911.7 KKK46008.1 - 1.2 9.2 0.1 1.2 9.2 0.1 3.3 3 1 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C 7TMR-DISM_7TM PF07695.11 KKK46008.1 - 1.3 8.9 27.0 5.4 6.8 27.2 1.9 1 1 0 1 1 1 0 7TM diverse intracellular signalling Ost5 PF05251.12 KKK46008.1 - 2.6 8.4 16.6 0.2 11.9 3.9 3.7 2 1 3 5 5 5 0 Oligosaccharyltransferase subunit 5 DUF2583 PF10762.9 KKK46008.1 - 4.4 7.8 9.5 0.11 12.9 1.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) PAS_3 PF08447.12 KKK46009.1 - 1.8e-47 159.5 7.8 1.2e-09 38.3 0.3 6.9 6 1 1 7 7 7 5 PAS fold PAS_9 PF13426.7 KKK46009.1 - 5.7e-44 148.6 21.7 5.6e-11 42.6 0.2 7.7 8 0 0 8 8 8 7 PAS domain PAS PF00989.25 KKK46009.1 - 8.8e-39 132.0 5.7 4.1e-10 39.7 0.0 7.3 7 0 0 7 7 7 6 PAS fold PAS_8 PF13188.7 KKK46009.1 - 1e-29 102.0 1.8 6.8e-07 29.2 0.0 7.3 7 0 0 7 7 7 6 PAS domain PAS_4 PF08448.10 KKK46009.1 - 4.5e-25 88.0 0.0 4.1e-07 30.2 0.0 7.5 7 0 0 7 7 7 6 PAS fold HATPase_c PF02518.26 KKK46009.1 - 4.5e-23 81.9 3.6 7.7e-23 81.1 0.8 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK46009.1 - 1.6e-14 53.7 0.6 5.7e-14 51.9 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 KKK46009.1 - 1.2e-11 44.7 0.4 0.0003 20.9 0.0 5.1 4 0 0 4 4 4 2 PAS domain PAS_7 PF12860.7 KKK46009.1 - 3e-05 24.2 10.7 7.7 6.7 0.0 8.7 9 2 0 9 9 9 1 PAS fold ATP-synt_F PF01990.17 KKK46009.1 - 0.0015 18.8 6.9 0.62 10.4 0.2 4.2 4 0 0 4 4 3 2 ATP synthase (F/14-kDa) subunit Imm52 PF15579.6 KKK46009.1 - 0.13 12.1 0.4 0.88 9.5 0.0 2.6 3 0 0 3 3 3 0 Immunity protein 52 DUF1829 PF08862.10 KKK46009.1 - 1.1 9.8 4.7 1.4 9.5 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF1829 Response_reg PF00072.24 KKK46010.1 - 9.3e-17 61.2 0.1 2.8e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KKK46010.1 - 1.5e-06 28.1 0.1 2.8e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain RHH_1 PF01402.21 KKK46010.1 - 0.046 13.7 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family MCPsignal PF00015.21 KKK46011.1 - 4.3e-32 111.3 21.1 1.1e-31 109.9 9.2 2.1 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 KKK46011.1 - 0.053 13.8 12.0 0.84 9.9 1.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 KKK46011.1 - 0.093 12.8 7.7 1.7 8.7 0.4 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4386 PF14329.6 KKK46011.1 - 0.13 12.1 4.1 0.13 12.1 2.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4386) PhageMin_Tail PF10145.9 KKK46011.1 - 0.17 11.7 14.2 0.95 9.3 7.1 2.2 1 1 1 2 2 2 0 Phage-related minor tail protein DUF1664 PF07889.12 KKK46011.1 - 0.43 10.6 6.9 3.5 7.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3739 PF12545.8 KKK46011.1 - 0.45 11.0 5.5 0.17 12.4 1.5 2.1 1 1 2 3 3 3 0 Filamentous haemagglutinin family outer membrane protein APG17 PF04108.12 KKK46011.1 - 0.63 9.1 6.7 4.3 6.3 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 LOH1CR12 PF10158.9 KKK46011.1 - 1.7 8.7 5.9 2.7 8.0 0.9 2.1 1 1 1 2 2 2 0 Tumour suppressor protein DUF148 PF02520.17 KKK46011.1 - 3.2 7.9 9.4 0.57 10.3 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 I_LWEQ PF01608.17 KKK46011.1 - 7.5 6.8 12.6 24 5.1 10.8 2.0 1 1 1 2 2 2 0 I/LWEQ domain FUSC PF04632.12 KKK46012.1 - 0.022 13.3 2.9 0.028 13.0 2.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4218 PF13960.6 KKK46012.1 - 0.052 13.2 1.6 0.19 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) DUF2207 PF09972.9 KKK46012.1 - 0.1 11.3 5.0 0.22 10.2 5.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) EamA PF00892.20 KKK46017.1 - 9.5e-38 129.5 44.8 1.5e-21 77.0 17.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1430 PF07242.11 KKK46017.1 - 0.054 13.8 1.2 0.054 13.8 1.2 4.0 3 2 1 5 5 5 0 Protein of unknown function (DUF1430) RseC_MucC PF04246.12 KKK46017.1 - 0.055 13.4 0.3 0.055 13.4 0.3 3.1 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC GPR_Gpa2_C PF11970.8 KKK46017.1 - 0.26 11.4 2.7 1.2 9.2 0.0 3.1 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term AMP-binding PF00501.28 KKK46018.1 - 5.7e-58 196.5 0.0 6.8e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK46018.1 - 0.0019 19.1 0.0 0.0041 18.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zinc_ribbon_12 PF11331.8 KKK46019.1 - 0.011 15.6 2.6 1.5 8.7 0.1 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain adh_short_C2 PF13561.6 KKK46020.1 - 2.9e-60 203.7 0.4 3.6e-60 203.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK46020.1 - 8.1e-47 159.2 0.3 1.2e-46 158.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KKK46020.1 - 3.4e-08 33.6 0.1 6.9e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK46020.1 - 0.00066 19.2 0.0 0.0012 18.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KKK46020.1 - 0.014 14.4 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KKK46020.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Ldh_1_N PF00056.23 KKK46020.1 - 0.031 14.4 0.1 0.051 13.7 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KKK46020.1 - 0.099 12.5 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KKK46020.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 KKK46023.1 - 1.9e-37 128.5 0.0 2.7e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KKK46023.1 - 6.2e-32 110.8 0.0 1.3e-31 109.7 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 KKK46023.1 - 0.054 13.0 0.1 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase zf-C2HE PF16278.5 KKK46024.1 - 0.17 12.3 2.0 0.52 10.8 0.9 1.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Fer4 PF00037.27 KKK46025.1 - 1.7e-05 24.4 2.1 1.7e-05 24.4 2.1 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_7 PF12838.7 KKK46025.1 - 0.00038 21.0 7.5 0.00069 20.1 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46025.1 - 0.0016 18.9 3.2 0.054 14.0 0.1 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK46025.1 - 0.0053 16.8 2.5 0.0053 16.8 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_16 PF13484.6 KKK46025.1 - 0.036 15.0 11.5 0.3 12.0 11.5 2.4 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK46025.1 - 0.062 13.5 9.7 0.46 10.7 10.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Dehalogenase PF13486.6 KKK46025.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Reductive dehalogenase subunit Fer4_10 PF13237.6 KKK46025.1 - 0.33 11.1 10.6 1.4 9.1 10.8 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK46025.1 - 3.3 7.9 8.9 8.9 6.5 8.9 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK46025.1 - 4.4 7.8 8.6 35 4.9 7.6 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain PIN PF01850.21 KKK46026.1 - 1.2e-14 54.8 0.2 2.6e-14 53.8 0.2 1.5 1 1 0 1 1 1 1 PIN domain Kin17_mid PF10357.9 KKK46026.1 - 0.013 15.4 0.7 0.043 13.7 0.2 1.9 1 1 1 2 2 2 0 Domain of Kin17 curved DNA-binding protein DUF658 PF04936.12 KKK46026.1 - 0.055 13.2 1.1 0.07 12.9 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF658) MraZ PF02381.18 KKK46027.1 - 0.00084 19.3 0.3 0.0016 18.4 0.3 1.7 1 1 0 1 1 1 1 MraZ protein, putative antitoxin-like MazE_antitoxin PF04014.18 KKK46027.1 - 0.0013 18.6 2.4 0.0032 17.4 2.4 1.6 1 1 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PEMT PF04191.13 KKK46028.1 - 1.6e-15 57.4 0.4 1.6e-15 57.4 0.4 1.9 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 KKK46028.1 - 0.00039 20.8 0.1 0.00039 20.8 0.1 1.9 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KKK46028.1 - 0.0013 17.6 0.0 0.0013 17.6 0.0 1.7 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KKK46028.1 - 0.006 16.6 3.5 0.0094 15.9 3.5 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KKK46028.1 - 0.027 14.0 0.4 0.051 13.1 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) PriA_CRR PF18319.1 KKK46029.1 - 0.0076 16.2 2.0 1.1 9.3 0.4 3.0 2 1 0 2 2 2 2 PriA DNA helicase Cys-rich region (CRR) domain E1-E2_ATPase PF00122.20 KKK46030.1 - 4.6e-49 166.4 4.3 4.6e-49 166.4 4.3 2.5 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK46030.1 - 3.3e-42 145.2 1.0 6.3e-42 144.2 1.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase YHS PF04945.13 KKK46030.1 - 2e-25 88.6 18.2 1.5e-12 47.4 3.3 2.9 3 0 0 3 3 3 2 YHS domain HMA PF00403.26 KKK46030.1 - 3.1e-18 66.0 0.3 2.7e-15 56.6 0.0 2.9 2 0 0 2 2 2 2 Heavy-metal-associated domain Arc_trans_TRASH PF08394.10 KKK46030.1 - 5.9e-07 29.7 7.4 0.00098 19.4 0.9 2.6 2 0 0 2 2 2 2 Archaeal TRASH domain Hydrolase_3 PF08282.12 KKK46030.1 - 0.0082 15.9 0.6 0.0082 15.9 0.6 4.0 4 1 2 6 6 6 1 haloacid dehalogenase-like hydrolase zf-FCS PF06467.14 KKK46030.1 - 0.016 15.1 8.9 1 9.3 0.5 3.3 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif CoA_binding_3 PF13727.6 KKK46030.1 - 0.13 12.3 1.6 1.1 9.2 0.6 2.5 2 0 0 2 2 2 0 CoA-binding domain FAP206 PF12018.8 KKK46030.1 - 0.43 10.0 4.5 4.5 6.7 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function E1-E2_ATPase PF00122.20 KKK46031.1 - 4.7e-54 182.7 0.2 4.7e-54 182.7 0.2 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KKK46031.1 - 4.3e-40 138.2 0.0 7.1e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KKK46031.1 - 3.2e-08 33.6 0.1 0.00053 19.8 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KKK46031.1 - 0.084 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK46031.1 - 0.18 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase 2-ph_phosp PF04029.14 KKK46033.1 - 6.1e-49 166.2 0.3 2.1e-48 164.5 0.3 1.7 1 1 0 1 1 1 1 2-phosphosulpholactate phosphatase HMA PF00403.26 KKK46034.1 - 9.8e-19 67.6 0.2 1.1e-18 67.5 0.2 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Thioredoxin_3 PF13192.6 KKK46034.1 - 0.11 12.6 0.3 0.13 12.3 0.1 1.4 2 0 0 2 2 2 0 Thioredoxin domain ParA PF10609.9 KKK46035.1 - 5e-92 307.8 0.1 6.4e-92 307.5 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KKK46035.1 - 4.1e-13 49.5 0.0 8.2e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KKK46035.1 - 3.7e-11 43.2 6.5 1.8e-09 37.8 6.5 2.3 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 KKK46035.1 - 5e-06 26.0 0.9 7.5e-06 25.4 0.9 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KKK46035.1 - 5.1e-06 25.9 1.1 5.1e-06 25.9 1.1 2.6 3 0 0 3 3 3 1 Anion-transporting ATPase APS_kinase PF01583.20 KKK46035.1 - 0.00034 20.5 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase MeaB PF03308.16 KKK46035.1 - 0.00053 19.1 0.2 0.00081 18.4 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KKK46035.1 - 0.00081 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 KKK46035.1 - 0.0028 17.2 0.9 0.0081 15.6 0.5 1.9 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KKK46035.1 - 0.0035 17.2 0.5 3 7.6 0.6 2.2 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KKK46035.1 - 0.0052 16.8 0.2 0.0088 16.1 0.2 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KKK46035.1 - 0.0065 15.9 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.17 KKK46035.1 - 0.007 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KKK46035.1 - 0.0072 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase VirC1 PF07015.11 KKK46035.1 - 0.0083 15.5 0.2 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 VirC1 protein TsaE PF02367.17 KKK46035.1 - 0.013 15.5 0.2 0.031 14.3 0.2 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CBP_BcsQ PF06564.12 KKK46035.1 - 0.016 14.7 0.6 0.16 11.4 0.3 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 KKK46035.1 - 0.017 14.4 0.2 0.027 13.7 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KKK46035.1 - 0.023 15.1 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KKK46035.1 - 0.025 15.1 1.6 0.025 15.1 0.1 1.8 2 0 0 2 2 1 0 AAA domain MobB PF03205.14 KKK46035.1 - 0.04 13.8 1.3 0.18 11.7 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KKK46035.1 - 0.055 13.4 0.6 0.14 12.0 0.6 1.7 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 KKK46035.1 - 0.062 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KKK46035.1 - 0.072 13.0 0.9 0.14 12.0 0.9 1.5 1 0 0 1 1 1 0 NACHT domain DnaB_C PF03796.15 KKK46035.1 - 0.087 12.1 0.3 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain T2SSE PF00437.20 KKK46035.1 - 0.09 11.8 0.5 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF853 PF05872.12 KKK46035.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CLP1_P PF16575.5 KKK46035.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 KKK46035.1 - 0.2 11.4 3.0 1 9.0 2.9 2.2 1 1 1 2 2 2 0 AAA domain CM_2 PF01817.21 KKK46036.1 - 0.07 13.5 0.2 0.081 13.3 0.2 1.2 1 0 0 1 1 1 0 Chorismate mutase type II Longin PF13774.6 KKK46037.1 - 0.016 15.2 0.4 0.029 14.4 0.0 1.6 2 0 0 2 2 2 0 Regulated-SNARE-like domain Csm1_B PF18211.1 KKK46037.1 - 0.016 15.0 0.2 0.029 14.2 0.2 1.3 1 0 0 1 1 1 0 Csm1 subunit domain B SRP-alpha_N PF04086.13 KKK46037.1 - 0.19 11.6 0.1 0.25 11.2 0.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal dCache_1 PF02743.18 KKK46037.1 - 0.35 10.6 1.7 3.8 7.2 1.3 2.0 1 1 1 2 2 2 0 Cache domain Ta0938 PF11494.8 KKK46037.1 - 0.37 11.1 4.4 0.16 12.3 1.1 2.0 2 1 0 2 2 2 0 Ta0938 zf-ribbon_3 PF13248.6 KKK46038.1 - 0.00048 19.4 1.2 0.0016 17.8 1.1 1.9 1 1 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK46038.1 - 0.002 17.8 0.6 0.0041 16.8 0.6 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK46038.1 - 0.0073 16.3 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_3 PF13920.6 KKK46038.1 - 0.067 13.1 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RsgA_N PF16745.5 KKK46038.1 - 0.16 11.7 0.1 0.48 10.2 0.1 1.8 1 1 0 1 1 1 0 RsgA N-terminal domain TF_Zn_Ribbon PF08271.12 KKK46038.1 - 0.3 10.6 3.0 0.89 9.1 3.0 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.12 KKK46038.1 - 1.8 8.6 4.7 65 3.6 4.9 2.5 1 1 1 2 2 2 0 PhnA Zinc-Ribbon E1-E2_ATPase PF00122.20 KKK46039.1 - 7.2e-53 178.8 1.2 7.2e-53 178.8 1.2 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK46039.1 - 3.1e-46 158.3 5.4 8e-46 157.0 4.6 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KKK46039.1 - 1.9e-28 98.7 8.2 1.4e-13 51.0 0.2 4.3 5 0 0 5 5 5 2 Heavy-metal-associated domain NES_C_h PF18208.1 KKK46039.1 - 2.5e-06 27.7 0.5 0.0034 17.6 0.1 2.7 2 0 0 2 2 2 2 Nicking enzyme C-terminal middle helical domain Hydrolase_3 PF08282.12 KKK46039.1 - 1.6e-05 24.8 8.8 0.00018 21.3 0.5 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase TusA PF01206.17 KKK46039.1 - 0.0029 17.4 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 Sulfurtransferase TusA HAD PF12710.7 KKK46039.1 - 0.014 15.8 0.0 0.073 13.5 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.6 KKK46039.1 - 0.019 15.1 4.9 1.4 9.1 0.3 3.0 2 1 1 3 3 3 0 Papain fold toxin 2 DUF4342 PF14242.6 KKK46039.1 - 0.16 12.0 0.1 0.16 12.0 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4342) Fer2_BFD PF04324.15 KKK46039.1 - 0.21 11.9 3.2 4.2 7.8 0.5 3.1 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain ABC2_membrane PF01061.24 KKK46040.1 - 4.4e-28 98.2 21.7 4.4e-28 98.2 21.7 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 KKK46040.1 - 3.8e-16 59.2 30.2 3.8e-16 59.2 30.2 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 KKK46040.1 - 2.3e-06 27.1 25.3 4.1e-06 26.3 25.3 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 KKK46040.1 - 0.00013 22.0 15.2 0.00013 22.0 15.2 2.3 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 KKK46041.1 - 2.4e-30 105.9 0.0 8.3e-30 104.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KKK46041.1 - 4.1e-13 49.8 1.3 9e-10 38.8 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KKK46041.1 - 0.00012 21.9 0.2 0.045 13.5 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 KKK46041.1 - 0.00031 21.4 1.4 0.00059 20.5 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) LUD_dom PF02589.15 KKK46041.1 - 0.008 15.9 0.1 5.5 6.7 0.0 2.9 2 1 0 2 2 2 2 LUD domain AAA PF00004.29 KKK46041.1 - 0.0083 16.6 2.1 0.12 12.8 0.3 3.2 1 1 2 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KKK46041.1 - 0.011 16.3 0.6 0.011 16.3 0.6 2.0 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 KKK46041.1 - 0.063 12.9 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SMC_N PF02463.19 KKK46041.1 - 0.072 12.5 0.2 2.6 7.4 0.0 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF5407 PF17401.2 KKK46041.1 - 0.096 13.0 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5407) MMR_HSR1 PF01926.23 KKK46041.1 - 0.097 12.8 0.2 9.1 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KKK46041.1 - 0.17 11.6 0.1 0.48 10.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain PEMT PF04191.13 KKK46042.1 - 2.8e-17 63.1 0.9 2.8e-17 63.1 0.9 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 KKK46042.1 - 3.2e-10 39.9 2.9 3.2e-10 39.9 2.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KKK46042.1 - 0.00018 21.8 0.2 0.00067 20.0 0.2 2.0 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KKK46042.1 - 0.00064 19.7 3.8 0.0013 18.7 3.3 1.8 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 KKK46042.1 - 0.0053 15.6 0.1 0.0053 15.6 0.1 2.1 1 1 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family SUR7 PF06687.12 KKK46042.1 - 0.16 11.6 10.2 0.39 10.3 7.3 2.1 1 1 1 2 2 2 0 SUR7/PalI family DUF202 PF02656.15 KKK46042.1 - 6.8 7.2 11.1 9.6 6.7 6.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Zn_ribbon_recom PF13408.6 KKK46043.1 - 1.6 9.3 9.7 17 6.0 0.1 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Desulfoferrod_N PF06397.12 KKK46043.1 - 2.9 7.6 19.8 2.5 7.8 8.2 3.7 3 2 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain ATPase_gene1 PF09527.10 KKK46044.1 - 0.33 11.2 9.6 0.94 9.7 0.6 2.1 1 1 1 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter AMP-binding PF00501.28 KKK46046.1 - 4.6e-93 312.1 0.0 5.5e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK46046.1 - 1.6e-19 70.6 0.3 4.8e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HATPase_c PF02518.26 KKK46050.1 - 3.5e-25 88.7 0.0 4.9e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KKK46050.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain RCC_reductase PF06405.11 KKK46050.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Acetyltransf_11 PF13720.6 KKK46051.1 - 0.01 16.3 1.0 0.011 16.1 1.0 1.1 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CDC45 PF02724.14 KKK46051.1 - 0.017 13.5 0.2 0.017 13.4 0.2 1.0 1 0 0 1 1 1 0 CDC45-like protein R-HINP1I PF11463.8 KKK46051.1 - 0.019 14.4 2.6 0.021 14.3 2.6 1.0 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease MerC PF03203.14 KKK46052.1 - 0.3 11.6 9.9 0.86 10.1 4.9 2.7 2 1 0 2 2 2 0 MerC mercury resistance protein DUF4173 PF13777.6 KKK46052.1 - 0.74 9.2 4.5 0.38 10.2 0.9 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4173) FAD_binding_4 PF01565.23 KKK46053.1 - 3.6e-29 101.3 0.1 7e-29 100.3 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 KKK46053.1 - 1.6e-05 24.7 0.0 0.00014 21.6 0.0 2.0 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain OS-D PF03392.13 KKK46054.1 - 0.019 15.0 2.5 0.02 15.0 2.5 1.0 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D DUF3850 PF12961.7 KKK46054.1 - 0.055 13.5 0.1 0.062 13.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Helicase_C PF00271.31 KKK46056.1 - 5.8e-23 81.4 0.3 3e-22 79.1 0.3 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC4 PF02732.15 KKK46056.1 - 1.5e-19 70.7 0.1 1.5e-19 70.7 0.1 2.2 2 1 0 2 2 2 1 ERCC4 domain ResIII PF04851.15 KKK46056.1 - 3.2e-12 46.8 0.5 1.5e-11 44.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KKK46056.1 - 1.3e-09 38.1 0.0 3.9e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_2 PF12826.7 KKK46056.1 - 2e-08 34.2 0.1 2.1e-07 31.0 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KKK46056.1 - 7.4e-08 32.9 2.5 1.2e-07 32.2 0.1 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain HHH PF00633.23 KKK46056.1 - 0.0049 16.7 0.1 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 KKK46056.1 - 0.042 14.5 0.0 0.042 14.5 0.0 4.1 5 0 0 5 5 5 0 5'-3' exonuclease, C-terminal SAM fold PND PF17949.1 KKK46056.1 - 0.044 14.0 1.0 0.074 13.3 0.1 1.9 2 0 0 2 2 2 0 FANCM pseudonuclease domain HHH_8 PF14716.6 KKK46056.1 - 0.046 14.1 0.2 0.69 10.3 0.0 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 KKK46056.1 - 0.093 12.5 0.1 0.093 12.5 0.1 3.2 3 0 0 3 3 3 0 Bacterial RNA polymerase, alpha chain C terminal domain HHH_3 PF12836.7 KKK46056.1 - 0.13 12.6 1.8 1.4 9.3 0.1 3.3 2 2 1 3 3 3 0 Helix-hairpin-helix motif Ras PF00071.22 KKK46057.1 - 2.1e-41 141.2 0.2 2.4e-41 141.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46057.1 - 3.9e-26 91.6 0.0 5.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46057.1 - 1.6e-11 44.0 0.1 2e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK46057.1 - 1.7e-05 24.8 0.1 2.8e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK46057.1 - 0.00018 21.0 0.1 0.0004 19.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DZR PF12773.7 KKK46057.1 - 0.00087 19.3 0.2 0.0014 18.6 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon Methyltransf_13 PF08421.11 KKK46057.1 - 0.0032 17.7 0.1 0.0055 16.9 0.1 1.3 1 0 0 1 1 1 1 Putative zinc binding domain zinc_ribbon_15 PF17032.5 KKK46057.1 - 0.0055 17.4 0.1 0.0075 17.0 0.1 1.3 1 0 0 1 1 1 1 zinc-ribbon family FeoB_N PF02421.18 KKK46057.1 - 0.0065 16.0 0.1 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 KKK46057.1 - 0.016 14.6 0.0 0.02 14.2 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KKK46057.1 - 0.021 14.9 0.1 0.048 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain zinc_ribbon_2 PF13240.6 KKK46057.1 - 0.028 14.2 3.8 0.065 13.0 3.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 KKK46057.1 - 0.11 12.6 1.4 0.22 11.7 1.4 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like GDP_Man_Dehyd PF16363.5 KKK46059.1 - 3.1e-07 30.1 0.0 4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK46059.1 - 6.9e-07 29.0 0.0 8.4e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KKK46059.1 - 0.0029 17.1 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KKK46059.1 - 0.007 15.4 0.0 0.0081 15.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF5104 PF17117.5 KKK46059.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) KR PF08659.10 KKK46059.1 - 0.017 15.0 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 KR domain ELFV_dehydrog PF00208.21 KKK46059.1 - 0.048 13.4 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Polysacc_synt_2 PF02719.15 KKK46059.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein COesterase PF00135.28 KKK46061.1 - 4.4e-18 65.4 0.3 4.6e-18 65.4 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family ECH_1 PF00378.20 KKK46062.1 - 7.4e-49 166.3 0.0 8.9e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KKK46062.1 - 2.2e-28 99.7 0.0 2.1e-25 89.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 KKK46063.1 - 8.5e-34 117.0 48.3 2.4e-27 95.8 15.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KKK46063.1 - 1.8e-10 40.2 16.9 5.1e-07 28.9 3.7 2.2 2 0 0 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 KKK46063.1 - 0.0022 16.9 18.9 0.0022 16.9 18.9 2.4 2 1 0 2 2 2 1 LacY proton/sugar symporter DUF5435 PF17503.2 KKK46063.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5435) CMD PF02627.20 KKK46064.1 - 9.9e-09 35.1 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family ACT PF01842.25 KKK46065.1 - 6.5e-06 25.8 0.4 0.00017 21.3 0.0 2.4 3 0 0 3 3 3 1 ACT domain ACT_4 PF13291.6 KKK46065.1 - 0.0084 16.7 0.0 0.063 13.9 0.0 2.0 2 0 0 2 2 2 1 ACT domain Thiolase_C PF02803.18 KKK46066.1 - 1.3e-40 137.8 0.4 2.6e-40 136.9 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 KKK46066.1 - 1.7e-26 93.2 0.0 3e-23 82.5 0.0 2.7 3 0 0 3 3 3 2 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 KKK46066.1 - 0.0069 16.0 0.4 0.57 9.7 0.0 2.9 2 2 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KKK46066.1 - 0.013 15.7 0.1 0.042 14.0 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal adh_short_C2 PF13561.6 KKK46067.1 - 2.1e-61 207.5 0.1 2.6e-61 207.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KKK46067.1 - 2.9e-57 193.3 2.2 5.8e-57 192.3 1.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KKK46067.1 - 1.7e-14 54.1 0.3 2.4e-14 53.6 0.3 1.1 1 0 0 1 1 1 1 KR domain DFP PF04127.15 KKK46067.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein OMPdecase PF00215.24 KKK46067.1 - 0.042 13.4 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NAD_binding_7 PF13241.6 KKK46067.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 KKK46068.1 - 3.7e-05 23.3 0.5 3.8e-05 23.2 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK46068.1 - 0.059 12.9 0.1 0.068 12.7 0.1 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HisKA_7TM PF16927.5 KKK46071.1 - 2.3e-08 34.4 18.4 2.8e-08 34.1 18.4 1.0 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase ABC2_membrane_3 PF12698.7 KKK46071.1 - 0.011 14.9 3.0 0.011 14.9 3.0 2.6 1 1 2 3 3 3 0 ABC-2 family transporter protein Gtr1_RagA PF04670.12 KKK46072.1 - 1.6e-18 66.9 4.9 2e-18 66.6 4.9 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK46072.1 - 2.5e-12 46.6 0.2 3.9e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK46072.1 - 2.3e-10 40.3 0.2 3.8e-10 39.6 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46072.1 - 5.6e-08 33.0 0.2 1.3e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK46072.1 - 1.9e-07 31.2 0.2 5.4e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KKK46072.1 - 0.0021 17.5 1.4 0.0036 16.8 1.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit HTH_36 PF13730.6 KKK46072.1 - 0.0042 17.0 0.6 0.0096 15.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4423 PF14394.6 KKK46072.1 - 0.007 16.1 0.1 0.017 14.8 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4423) AAA PF00004.29 KKK46072.1 - 0.011 16.1 1.6 0.22 11.9 0.2 2.6 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2250 PF10007.9 KKK46072.1 - 0.019 15.0 1.2 0.037 14.1 0.1 2.0 2 2 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) FeoB_N PF02421.18 KKK46072.1 - 0.034 13.7 0.5 0.1 12.1 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SUB1_ProdP9 PF18213.1 KKK46072.1 - 0.036 13.9 1.2 0.13 12.2 0.2 2.4 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 RNA_pol_Rpb5_C PF01191.19 KKK46072.1 - 0.1 12.5 0.5 0.1 12.5 0.5 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain GTP_EFTU PF00009.27 KKK46072.1 - 0.16 11.5 0.4 0.31 10.5 0.1 1.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Response_reg PF00072.24 KKK46073.1 - 2.4e-24 85.7 0.0 2.7e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain AbiEi_4 PF13338.6 KKK46074.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin PRF PF06875.11 KKK46075.1 - 0.082 12.3 0.1 0.083 12.3 0.1 1.1 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF UPF0242 PF06785.11 KKK46077.1 - 0.0015 18.7 2.2 0.0016 18.6 2.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Med2 PF11214.8 KKK46077.1 - 0.013 15.7 5.3 0.064 13.4 1.2 2.3 1 1 1 2 2 2 0 Mediator complex subunit 2 ALIX_LYPXL_bnd PF13949.6 KKK46077.1 - 0.025 13.9 4.1 0.034 13.5 4.1 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV WEMBL PF05701.11 KKK46077.1 - 0.029 13.1 1.3 0.025 13.3 1.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF948 PF06103.11 KKK46077.1 - 0.032 14.5 0.9 0.96 9.8 0.1 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3510 PF12022.8 KKK46077.1 - 0.045 14.1 0.2 0.057 13.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Fib_alpha PF08702.10 KKK46077.1 - 0.052 13.7 5.2 0.082 13.1 4.1 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IL15 PF02372.15 KKK46077.1 - 0.079 13.0 1.2 0.16 12.0 0.4 1.8 1 1 0 1 1 1 0 Interleukin 15 Amino_oxidase PF01593.24 KKK46077.1 - 0.1 11.9 0.2 0.12 11.7 0.2 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Cauli_DNA-bind PF03310.13 KKK46077.1 - 0.1 12.7 0.3 0.23 11.5 0.2 1.7 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein PilJ PF13675.6 KKK46077.1 - 0.13 12.3 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2207 PF09972.9 KKK46082.1 - 0.0079 15.0 1.6 0.009 14.8 1.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) INTS2 PF14750.6 KKK46082.1 - 0.078 10.5 0.3 0.091 10.3 0.3 1.0 1 0 0 1 1 1 0 Integrator complex subunit 2 LPD18 PF18832.1 KKK46083.1 - 0.03 14.4 0.1 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 LRR_8 PF13855.6 KKK46085.1 - 6.8e-44 147.5 105.7 1.2e-09 37.8 7.0 7.1 3 2 6 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 KKK46085.1 - 3.6e-28 97.1 89.1 4.2e-07 30.2 2.7 9.2 1 1 12 13 13 13 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KKK46085.1 - 2.4e-06 27.3 77.4 0.97 10.2 0.5 14.4 15 0 0 15 15 15 7 Leucine Rich Repeat LRR_5 PF13306.6 KKK46085.1 - 0.003 17.5 17.8 0.13 12.2 2.4 3.8 1 1 2 4 4 4 4 BspA type Leucine rich repeat region (6 copies) TF_Zn_Ribbon PF08271.12 KKK46085.1 - 0.045 13.3 1.1 0.092 12.3 1.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding RPA_interact_C PF14768.6 KKK46085.1 - 0.16 12.5 0.2 0.34 11.5 0.2 1.6 1 0 0 1 1 1 0 Replication protein A interacting C-terminal LEDGF PF11467.8 KKK46085.1 - 0.2 11.3 5.9 3.6 7.2 0.4 4.2 4 0 0 4 4 4 0 Lens epithelium-derived growth factor (LEDGF) Peptidase_C21 PF05381.12 KKK46085.1 - 0.32 11.4 2.7 1 9.7 0.1 2.8 3 0 0 3 3 3 0 Tymovirus endopeptidase Ras PF00071.22 KKK46086.1 - 7.6e-24 84.1 1.4 1.1e-23 83.6 0.6 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KKK46086.1 - 1.6e-15 57.4 0.4 2.7e-15 56.7 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KKK46087.1 - 1.2e-32 112.7 0.0 1.9e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46087.1 - 7e-19 68.2 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46087.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3671 PF12420.8 KKK46087.1 - 0.97 9.5 12.7 0.37 10.9 9.5 1.9 2 0 0 2 2 2 0 Protein of unknown function TPR_MalT PF17874.1 KKK46089.1 - 1.5e-21 77.2 9.4 1e-08 35.0 0.0 4.6 1 1 3 4 4 4 4 MalT-like TPR region TPR_12 PF13424.6 KKK46089.1 - 2.1e-19 69.6 16.4 3.3e-06 27.3 0.4 5.7 4 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KKK46089.1 - 1.3e-11 43.7 28.3 0.046 13.9 0.5 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KKK46089.1 - 6.1e-11 41.7 26.3 0.0034 17.1 1.2 7.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 KKK46089.1 - 2e-10 39.9 12.4 0.18 11.9 0.7 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KKK46089.1 - 3.1e-06 26.9 31.7 0.013 15.6 0.7 8.5 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 KKK46089.1 - 1.8e-05 24.5 11.7 1.8 8.5 0.8 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KKK46089.1 - 0.0046 17.1 11.7 0.35 11.1 0.6 5.5 4 1 2 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KKK46089.1 - 0.0093 16.7 5.9 25 6.0 0.1 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KKK46089.1 - 0.064 13.0 4.9 0.74 9.5 0.2 3.2 1 1 0 2 2 2 0 26S proteasome subunit RPN7 HTH_Bact PF18768.1 KKK46089.1 - 0.087 12.4 3.0 0.24 11.0 0.7 3.1 3 1 0 3 3 3 0 Helix-turn-helix bacterial domain TPR_21 PF09976.9 KKK46089.1 - 0.092 12.4 8.2 1.8 8.3 0.6 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 KKK46089.1 - 0.11 13.2 2.8 1.5 9.5 0.5 3.8 4 1 0 4 4 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KKK46089.1 - 0.13 11.9 12.9 1.6 8.5 0.2 4.6 5 0 0 5 5 5 0 TPR repeat TPR_6 PF13174.6 KKK46089.1 - 0.25 12.1 11.9 1.9 9.3 0.0 6.3 8 0 0 8 8 6 0 Tetratricopeptide repeat DUF4398 PF14346.6 KKK46089.1 - 0.31 11.7 4.0 5.5 7.7 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) YfdX PF10938.8 KKK46089.1 - 0.38 10.7 4.5 0.6 10.0 0.2 3.2 4 1 0 4 4 4 0 YfdX protein TPR_17 PF13431.6 KKK46089.1 - 8.1 7.1 7.6 54 4.5 0.4 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat OB_aCoA_assoc PF01796.17 KKK46090.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.4 2 0 0 2 2 2 1 DUF35 OB-fold domain, acyl-CoA-associated LSM PF01423.22 KKK46090.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 LSM domain Fe-ADH PF00465.19 KKK46091.1 - 4.3e-25 88.3 0.2 5e-25 88.1 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK46091.1 - 4.3e-05 23.4 0.1 5.1e-05 23.1 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF2240 PF09999.9 KKK46094.1 - 0.0016 18.0 0.1 0.0069 16.0 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2240) DNA_pol_E_B PF04042.16 KKK46095.1 - 4.8e-12 45.7 0.0 8.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 KKK46095.1 - 1.8e-10 41.6 0.3 3.6e-10 40.7 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA_anti-codon PF01336.25 KKK46095.1 - 5.2e-06 26.4 0.2 1.4e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 KKK46095.1 - 0.0016 18.4 0.0 0.74 9.9 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4539) OTCace_N PF02729.21 KKK46095.1 - 0.015 15.3 0.3 0.061 13.3 0.2 1.9 1 1 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Metallophos_2 PF12850.7 KKK46095.1 - 0.02 15.1 0.0 0.048 13.9 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain tRNA_anti_2 PF13742.6 KKK46095.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain PolC_DP2 PF03833.13 KKK46096.1 - 0 1105.4 0.0 0 1104.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.12 KKK46096.1 - 0.065 13.2 16.1 2.4 8.2 0.0 3.0 2 1 0 2 2 2 0 zinc-ribbons HypA PF01155.19 KKK46096.1 - 0.073 13.1 15.2 1.9 8.5 0.1 3.5 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 KKK46096.1 - 0.9 9.0 21.5 6.7 6.3 0.1 5.3 5 0 0 5 5 5 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KKK46096.1 - 1.4 9.0 5.3 42 4.3 0.1 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 KKK46096.1 - 4.4 7.5 20.3 1.5 9.0 0.9 4.2 2 1 2 4 4 4 0 Zinc ribbon domain AAA PF00004.29 KKK46099.1 - 5.2e-45 153.1 0.5 6.8e-44 149.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KKK46099.1 - 2.4e-14 53.0 0.0 8.2e-14 51.3 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KKK46099.1 - 4.5e-12 45.6 0.7 9.3e-12 44.6 0.7 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK46099.1 - 1.1e-07 32.4 1.6 0.00055 20.4 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 KKK46099.1 - 2.1e-06 28.0 0.9 2e-05 24.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK46099.1 - 3.6e-06 26.8 0.0 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KKK46099.1 - 5.8e-06 26.3 0.2 0.00012 22.1 0.2 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 KKK46099.1 - 3.8e-05 23.3 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 KKK46099.1 - 4.3e-05 22.8 0.0 0.00013 21.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KKK46099.1 - 0.00014 22.1 1.6 0.0011 19.2 0.3 2.5 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KKK46099.1 - 0.0013 18.6 0.0 0.0036 17.1 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 KKK46099.1 - 0.0018 17.5 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 KKK46099.1 - 0.0032 18.0 0.3 0.0079 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KKK46099.1 - 0.0055 17.0 0.5 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KKK46099.1 - 0.0072 15.7 0.1 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KKK46099.1 - 0.0083 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KKK46099.1 - 0.009 15.9 0.2 0.47 10.3 0.0 2.3 1 1 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KKK46099.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KKK46099.1 - 0.013 15.4 0.6 0.3 11.0 0.0 2.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 KKK46099.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KKK46099.1 - 0.019 14.7 0.7 0.042 13.6 0.1 1.9 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KKK46099.1 - 0.021 15.2 0.0 0.052 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KKK46099.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KKK46099.1 - 0.031 13.6 0.0 0.088 12.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 KKK46099.1 - 0.035 13.9 0.8 0.22 11.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KKK46099.1 - 0.035 13.8 0.1 0.16 11.6 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KKK46099.1 - 0.043 12.9 0.0 0.092 11.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 KKK46099.1 - 0.058 13.3 0.2 0.19 11.6 0.0 2.0 2 0 0 2 2 1 0 NTPase PhoH PF02562.16 KKK46099.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KKK46099.1 - 0.074 12.8 0.1 0.17 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK46099.1 - 0.096 12.3 0.3 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KKK46099.1 - 0.1 12.9 0.0 0.35 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 KKK46099.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KKK46099.1 - 0.12 12.9 0.1 0.57 10.7 0.0 2.0 2 1 0 2 2 2 0 ABC transporter ATPase PF06745.13 KKK46099.1 - 0.15 11.3 0.0 0.15 11.3 0.0 2.9 4 0 0 4 4 4 0 KaiC APG6_N PF17675.1 KKK46099.1 - 3.7 8.1 9.5 1.7 9.2 6.5 1.9 2 0 0 2 2 1 0 Apg6 coiled-coil region CENP-Q PF13094.6 KKK46099.1 - 6.2 7.0 10.3 4.7 7.4 6.9 2.3 3 0 0 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TGT_C2 PF14810.6 KKK46100.1 - 2.2e-17 63.0 0.0 3.6e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Patch-forming domain C2 of tRNA-guanine transglycosylase PUA PF01472.20 KKK46100.1 - 4.8e-13 48.9 0.1 6.5e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KKK46100.1 - 7.3e-07 29.4 0.1 2.8e-06 27.5 0.1 2.0 1 1 1 2 2 2 1 UPF0113 PUA domain GIT_SHD PF08518.11 KKK46100.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT NAC PF01849.18 KKK46101.1 - 2.4e-10 40.2 0.5 4.6e-10 39.3 0.5 1.5 1 0 0 1 1 1 1 NAC domain DMA PF03474.14 KKK46101.1 - 0.0046 16.5 0.1 0.0085 15.7 0.1 1.4 1 0 0 1 1 1 1 DMRTA motif HOIP-UBA PF16678.5 KKK46101.1 - 0.063 13.3 0.3 0.73 9.8 0.1 2.2 1 1 1 2 2 2 0 HOIP UBA domain pair Cupin_2 PF07883.11 KKK46103.1 - 2.9e-10 39.7 0.2 3.5e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KKK46103.1 - 1.1e-06 28.6 0.2 1.4e-06 28.3 0.2 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain PCO_ADO PF07847.12 KKK46103.1 - 0.00015 21.3 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 PCO_ADO Ectoine_synth PF06339.12 KKK46103.1 - 0.002 18.3 0.2 0.0023 18.1 0.2 1.2 1 0 0 1 1 1 1 Ectoine synthase Cupin_1 PF00190.22 KKK46103.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Cupin NRDD PF13597.6 KKK46104.1 - 1.6e-135 453.1 0.0 2e-135 452.8 0.0 1.0 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase HypA PF01155.19 KKK46104.1 - 0.013 15.5 0.1 0.086 12.9 0.2 2.2 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 KKK46104.1 - 0.13 12.3 1.1 0.28 11.2 1.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon tRNA_anti_2 PF13742.6 KKK46104.1 - 0.15 12.3 0.0 0.51 10.6 0.0 1.8 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Pyridoxal_deC PF00282.19 KKK46106.1 - 1.1e-34 119.8 0.0 3.5e-34 118.2 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KKK46106.1 - 3e-12 46.2 0.0 6.1e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK46106.1 - 8.4e-08 31.8 0.0 1.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK46106.1 - 2.4e-06 27.1 0.0 3.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KKK46106.1 - 0.00084 18.8 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DZR PF12773.7 KKK46107.1 - 2e-06 27.7 5.3 0.017 15.1 0.3 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK46107.1 - 5.1e-05 23.9 7.6 0.084 13.6 0.3 2.6 2 0 0 2 2 2 2 zinc-ribbon family zf-ribbon_3 PF13248.6 KKK46107.1 - 0.0021 17.4 14.6 0.0077 15.6 1.4 3.4 3 0 0 3 3 3 2 zinc-ribbon domain zf-C4H2 PF10146.9 KKK46107.1 - 0.0022 18.4 0.9 0.0022 18.4 0.9 1.4 2 0 0 2 2 2 1 Zinc finger-containing protein Rubredoxin_2 PF18073.1 KKK46107.1 - 0.0079 15.9 5.7 0.0079 15.9 5.7 2.3 2 0 0 2 2 2 1 Rubredoxin metal binding domain zf-C3HC4_3 PF13920.6 KKK46107.1 - 0.0097 15.7 8.0 0.11 12.3 1.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KKK46107.1 - 0.034 13.8 6.8 0.15 11.7 0.8 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type ANT PF03374.14 KKK46107.1 - 0.037 14.3 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain TackOD1 PF18551.1 KKK46107.1 - 0.064 12.9 4.7 2.5 7.7 0.3 2.4 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 KKK46107.1 - 0.079 13.0 4.8 0.78 9.8 0.6 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_1 PF14446.6 KKK46107.1 - 0.14 12.1 6.5 2.7 8.0 0.5 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Mut7-C PF01927.16 KKK46107.1 - 0.52 10.4 3.5 4.5 7.4 0.1 2.6 2 1 1 3 3 3 0 Mut7-C RNAse domain zf-RING_10 PF16685.5 KKK46107.1 - 0.77 9.9 5.2 0.45 10.7 0.3 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zinc_ribbon_2 PF13240.6 KKK46107.1 - 0.78 9.5 15.1 3.5 7.5 2.3 3.2 2 2 0 2 2 2 0 zinc-ribbon domain zf-IS66 PF13005.7 KKK46107.1 - 1.4 9.4 7.3 7.5 7.0 0.0 4.3 5 0 0 5 5 5 0 zinc-finger binding domain of transposase IS66 Zn-ribbon_8 PF09723.10 KKK46107.1 - 2.4 8.3 9.8 24 5.1 0.0 3.6 3 1 0 3 3 3 0 Zinc ribbon domain FYDLN_acid PF09538.10 KKK46107.1 - 3.3 8.4 4.8 1.2 9.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DNA_ligase_ZBD PF03119.16 KKK46107.1 - 4 7.6 5.7 20 5.3 0.2 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF3797 PF12677.7 KKK46107.1 - 4.4 7.3 10.1 2.6 8.0 0.1 3.0 3 1 0 3 3 2 0 Domain of unknown function (DUF3797) Ras PF00071.22 KKK46108.1 - 2e-34 118.6 0.0 3.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46108.1 - 4e-18 65.8 0.0 1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46108.1 - 1.6e-05 24.4 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family zinc_ribbon_15 PF17032.5 KKK46108.1 - 0.0034 18.1 0.6 0.0034 18.1 0.6 2.4 2 1 0 2 2 1 1 zinc-ribbon family DZR PF12773.7 KKK46108.1 - 0.0035 17.3 1.0 0.006 16.6 1.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon ATP_bind_1 PF03029.17 KKK46108.1 - 0.0068 16.2 2.9 0.0082 15.9 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein zinc_ribbon_2 PF13240.6 KKK46108.1 - 0.0087 15.7 2.4 0.018 14.7 2.4 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK46108.1 - 0.012 14.9 2.0 0.023 14.1 2.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain GTP_EFTU PF00009.27 KKK46108.1 - 0.058 12.9 0.0 0.058 12.9 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Nudix_N_2 PF14803.6 KKK46108.1 - 0.42 10.6 1.3 38 4.3 0.0 2.7 2 0 0 2 2 2 0 Nudix N-terminal A2L_zn_ribbon PF08792.10 KKK46108.1 - 0.45 10.3 5.4 1.1 9.0 5.4 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain RR_TM4-6 PF06459.12 KKK46108.1 - 0.72 9.6 16.1 1.7 8.4 16.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tho2 PF11262.8 KKK46108.1 - 0.73 9.0 7.7 1.3 8.2 7.7 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CPSF100_C PF13299.6 KKK46108.1 - 1 9.5 9.7 2.4 8.3 9.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HSP70 PF00012.20 KKK46108.1 - 1.9 6.6 9.0 2.7 6.0 9.0 1.1 1 0 0 1 1 1 0 Hsp70 protein NARP1 PF12569.8 KKK46108.1 - 2 7.2 19.1 2.8 6.7 19.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_23 PF13476.6 KKK46108.1 - 2.2 8.7 18.0 4.2 7.8 18.0 1.4 1 0 0 1 1 1 0 AAA domain MCM_bind PF09739.9 KKK46108.1 - 2.6 6.4 12.1 3.8 5.9 12.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 KKK46108.1 - 3.9 6.4 10.7 5.5 5.9 10.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 KKK46108.1 - 4.3 6.1 6.6 6.2 5.6 6.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2151 PF10221.9 KKK46108.1 - 5.1 5.6 14.1 7.3 5.1 14.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Sec62 PF03839.16 KKK46108.1 - 7.7 6.0 20.1 15 5.0 20.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 KKK46108.1 - 8.1 5.1 15.7 12 4.6 15.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 KKK46108.1 - 9.3 4.4 13.4 10 4.3 11.8 1.8 2 0 0 2 2 2 0 CDC45-like protein Ras PF00071.22 KKK46109.1 - 1.1e-09 38.2 0.7 1.2e-09 38.0 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46109.1 - 3.3e-07 30.6 0.2 3.8e-07 30.3 0.2 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KKK46109.1 - 0.092 12.3 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KKK46109.1 - 0.11 12.8 0.1 0.12 12.8 0.1 1.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KKK46109.1 - 0.16 11.5 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region Aminotran_4 PF01063.19 KKK46112.1 - 3.2e-38 131.8 0.0 3.8e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Ras PF00071.22 KKK46113.1 - 9.6e-32 109.8 0.2 1.1e-31 109.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46113.1 - 2.8e-23 82.4 0.1 3.7e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46113.1 - 3.7e-07 29.7 0.1 4e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KKK46113.1 - 0.00047 20.2 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KKK46113.1 - 0.00057 20.3 0.0 0.00076 19.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KKK46113.1 - 0.0035 16.8 0.1 0.008 15.6 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KKK46113.1 - 0.0043 16.4 0.1 0.0056 16.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DAP3 PF10236.9 KKK46113.1 - 0.0082 15.3 0.1 0.016 14.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 CbiA PF01656.23 KKK46113.1 - 0.022 14.8 0.1 0.038 14.0 0.1 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KKK46113.1 - 0.027 14.2 0.4 0.22 11.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 KKK46113.1 - 0.032 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KKK46113.1 - 0.033 13.5 0.3 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 KKK46113.1 - 0.065 13.1 0.2 0.62 10.0 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 KKK46113.1 - 0.084 12.8 0.0 0.98 9.3 0.0 2.1 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 KKK46113.1 - 0.11 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 KKK46113.1 - 0.18 11.6 1.1 2.2 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NAD_binding_10 PF13460.6 KKK46114.1 - 6.1e-06 26.2 0.0 6.6e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Fer4 PF00037.27 KKK46116.1 - 2.1e-14 52.6 16.2 4.5e-07 29.4 5.9 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK46116.1 - 1.7e-11 44.1 20.6 7.8e-09 35.6 10.5 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK46116.1 - 4.2e-11 42.4 14.8 8.6e-07 28.8 1.5 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK46116.1 - 5.1e-11 43.0 24.4 2.7e-08 34.3 12.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46116.1 - 1.4e-09 38.0 25.4 4.7e-07 29.8 13.4 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK46116.1 - 1.6e-09 37.3 10.7 2.8e-05 23.9 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK46116.1 - 2.8e-09 37.0 11.5 7.3e-05 22.8 1.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46116.1 - 3.9e-08 34.1 10.4 0.00074 20.4 1.4 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK46116.1 - 7.7e-08 32.3 9.2 0.00016 21.9 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK46116.1 - 4.2e-07 30.3 9.0 0.0011 19.3 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK46116.1 - 1.3e-05 25.9 8.9 0.021 15.6 0.8 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK46116.1 - 1.7e-05 25.4 22.0 0.0016 19.2 6.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KKK46116.1 - 1.9e-05 25.1 7.7 0.029 14.9 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK46116.1 - 2.5e-05 24.9 7.8 0.0011 19.7 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.6 KKK46116.1 - 0.0047 17.4 13.3 0.28 11.7 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KKK46116.1 - 0.2 11.9 12.8 2.4 8.4 12.8 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Desulfoferrod_N PF06397.12 KKK46116.1 - 5 6.8 16.6 0.086 12.5 3.8 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Antibiotic_NAT PF02522.14 KKK46117.1 - 8.9e-78 261.1 0.0 1.1e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase DUF2057 PF09829.9 KKK46117.1 - 0.021 15.0 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Hexapep PF00132.24 KKK46118.1 - 3.4e-17 61.4 19.0 2.2e-06 27.1 0.2 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) HAS-barrel PF09378.10 KKK46118.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 HAS barrel domain Hexapep_2 PF14602.6 KKK46118.1 - 0.16 11.8 17.9 2.2 8.1 5.3 4.6 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase MaoC_dehydratas PF01575.19 KKK46119.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.4 1 1 0 1 1 1 1 MaoC like domain XFP_N PF09364.10 KKK46120.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain AHSA1 PF08327.11 KKK46123.1 - 7.8e-10 39.1 0.9 9e-10 38.9 0.9 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Stealth_CR1 PF17101.5 KKK46123.1 - 0.33 10.7 2.1 0.33 10.7 0.8 1.7 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 DUF4088 PF13317.6 KKK46124.1 - 0.095 12.3 0.1 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) DUF4430 PF14478.6 KKK46125.1 - 0.0092 16.6 5.1 0.011 16.4 0.7 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4430) EII-GUT PF03608.13 KKK46125.1 - 0.07 13.0 0.6 0.14 12.1 0.6 1.4 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Robl_LC7 PF03259.17 KKK46126.1 - 5e-10 39.0 0.1 7.9e-10 38.4 0.1 1.3 1 1 0 1 1 1 1 Roadblock/LC7 domain Terminase_2 PF03592.16 KKK46126.1 - 0.071 13.6 0.4 0.076 13.5 0.4 1.2 1 1 0 1 1 1 0 Terminase small subunit GTP_EFTU PF00009.27 KKK46127.1 - 2e-31 109.1 0.6 3.5e-31 108.3 0.6 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KKK46127.1 - 7.9e-09 35.8 0.8 2.3e-08 34.3 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KKK46127.1 - 5.3e-05 23.3 0.1 0.00016 21.7 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KKK46127.1 - 0.005 16.7 2.8 0.0069 16.3 0.1 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 4 FeoB_N PF02421.18 KKK46127.1 - 0.0059 16.1 0.1 0.017 14.6 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 KKK46127.1 - 0.042 13.0 2.3 0.17 11.0 1.1 2.1 2 0 0 2 2 2 0 G-protein alpha subunit adh_short PF00106.25 KKK46128.1 - 3.3e-47 160.5 0.8 4.6e-47 160.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK46128.1 - 2.2e-27 96.1 0.0 3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK46128.1 - 3.2e-10 40.2 0.3 4.8e-10 39.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KKK46128.1 - 0.0019 17.7 0.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KKK46128.1 - 0.0026 18.0 0.1 0.0044 17.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KKK46128.1 - 0.0034 17.3 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KKK46128.1 - 0.0044 16.2 0.1 0.0074 15.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KKK46128.1 - 0.032 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KKK46128.1 - 0.033 14.1 2.1 0.24 11.3 0.4 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KKK46128.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.16 KKK46128.1 - 0.098 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-ribbon_3 PF13248.6 KKK46129.1 - 2.5e-05 23.5 4.2 4.3e-05 22.8 4.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KKK46129.1 - 9.1e-05 22.0 5.5 0.00018 21.1 5.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 KKK46129.1 - 0.0006 19.8 0.6 0.0011 18.9 0.6 1.3 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 KKK46129.1 - 0.001 18.9 4.5 0.29 11.1 0.1 2.5 2 0 0 2 2 2 2 Nudix N-terminal zf-NADH-PPase PF09297.11 KKK46129.1 - 0.3 10.8 3.5 0.69 9.6 3.5 1.6 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-HIT PF04438.16 KKK46129.1 - 1.3 8.9 4.0 9.9 6.1 0.2 2.3 2 0 0 2 2 2 0 HIT zinc finger NOB1_Zn_bind PF08772.11 KKK46129.1 - 1.8 8.8 4.6 55 4.0 4.8 2.7 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like THAP PF05485.12 KKK46131.1 - 0.036 15.0 1.5 0.073 14.0 1.5 1.5 1 1 0 1 1 1 0 THAP domain NUDIX PF00293.28 KKK46132.1 - 8.1e-13 48.6 0.0 1.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 KKK46133.1 - 4.9e-12 46.0 0.0 6.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NifQ PF04891.12 KKK46134.1 - 0.27 11.6 3.4 0.32 11.3 3.4 1.1 1 0 0 1 1 1 0 NifQ Aldo_ket_red PF00248.21 KKK46135.1 - 1.8e-37 129.1 0.7 3.4e-37 128.2 0.7 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Fer4_17 PF13534.6 KKK46135.1 - 3e-10 40.5 3.1 7.7e-10 39.2 3.1 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46135.1 - 1.2e-08 35.0 2.9 3.1e-08 33.6 2.9 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK46135.1 - 1.3e-06 28.7 1.1 3.3e-06 27.5 1.2 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK46135.1 - 2.2e-05 24.6 0.6 0.038 14.2 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46135.1 - 2.2e-05 24.5 4.0 8.4e-05 22.6 4.2 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46135.1 - 2.8e-05 24.6 4.1 0.00013 22.5 4.1 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 KKK46135.1 - 5.6e-05 22.9 2.0 0.00043 20.0 0.3 2.3 2 0 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_16 PF13484.6 KKK46135.1 - 0.001 20.0 3.8 0.041 14.8 0.5 2.9 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 KKK46135.1 - 0.0036 18.1 1.3 0.7 10.8 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46135.1 - 0.0057 16.4 2.3 0.0057 16.4 2.3 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Chalcone PF02431.15 KKK46135.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Fer4_6 PF12837.7 KKK46135.1 - 0.031 14.4 2.3 0.031 14.4 2.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 KKK46135.1 - 0.072 13.2 6.3 0.54 10.4 1.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain GGGtGRT PF14057.6 KKK46135.1 - 0.079 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 GGGtGRT protein Sacchrp_dh_NADP PF03435.18 KKK46135.1 - 0.11 12.8 0.1 0.37 11.1 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Fer4_4 PF12800.7 KKK46135.1 - 0.16 12.5 12.2 0.13 12.8 3.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK46135.1 - 1.3 9.3 15.0 0.44 10.7 2.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Lactamase_B PF00753.27 KKK46137.1 - 2.8e-17 63.4 0.0 3.7e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KKK46137.1 - 0.0045 16.5 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain L51_S25_CI-B8 PF05047.16 KKK46137.1 - 0.079 12.9 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Fer4 PF00037.27 KKK46142.1 - 7.9e-08 31.8 12.8 0.00045 19.9 2.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK46142.1 - 3.3e-06 27.2 11.3 4.8e-06 26.6 11.3 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46142.1 - 0.00011 23.1 4.1 0.039 14.9 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_13 PF13370.6 KKK46142.1 - 0.00011 22.6 2.7 0.00011 22.6 2.7 2.1 1 1 1 2 2 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_2 PF12797.7 KKK46142.1 - 0.00011 22.0 12.1 0.0041 17.1 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 KKK46142.1 - 0.00038 21.1 10.3 0.008 16.9 0.9 2.1 1 1 1 2 2 2 2 4Fe-4S single cluster domain Fer4_10 PF13237.6 KKK46142.1 - 0.0011 19.0 12.6 0.0021 18.1 12.6 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46142.1 - 0.0016 19.0 13.1 0.076 13.6 15.0 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK46142.1 - 0.0016 18.4 13.8 0.048 13.8 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KKK46142.1 - 0.0034 17.8 8.7 0.38 11.4 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK46142.1 - 0.017 15.5 14.5 0.36 11.3 14.7 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK46142.1 - 0.055 13.6 11.9 0.28 11.3 12.2 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46142.1 - 0.07 13.7 16.1 5.4 7.6 3.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Pox_A3L PF05288.11 KKK46142.1 - 2.2 8.3 7.2 0.31 11.0 1.6 2.0 1 1 1 2 2 2 0 Poxvirus A3L Protein Thioredoxin_3 PF13192.6 KKK46142.1 - 2.7 8.1 5.5 8.2 6.6 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin domain Fer4_3 PF12798.7 KKK46142.1 - 4.7 8.4 14.9 1.3 10.1 3.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain MeaB PF03308.16 KKK46144.1 - 1.5e-79 266.8 0.0 1.8e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KKK46144.1 - 0.00032 20.0 0.5 0.00064 19.0 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain DUF87 PF01935.17 KKK46144.1 - 0.00054 20.1 1.8 0.023 14.8 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 KKK46144.1 - 0.00058 19.5 0.4 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KKK46144.1 - 0.0006 19.9 0.2 0.0021 18.1 0.2 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KKK46144.1 - 0.00065 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KKK46144.1 - 0.00077 19.4 3.7 0.0019 18.2 0.3 2.4 2 0 0 2 2 2 1 NTPase ATP_bind_1 PF03029.17 KKK46144.1 - 0.0012 18.7 0.3 0.0052 16.6 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KKK46144.1 - 0.0012 19.4 1.2 0.0028 18.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KKK46144.1 - 0.0021 18.5 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ParA PF10609.9 KKK46144.1 - 0.0044 16.5 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase RsgA_GTPase PF03193.16 KKK46144.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KKK46144.1 - 0.0056 17.2 0.1 0.017 15.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 KKK46144.1 - 0.0063 16.9 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase KTI12 PF08433.10 KKK46144.1 - 0.007 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.6 KKK46144.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 KKK46144.1 - 0.02 14.6 0.4 0.045 13.5 0.2 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.14 KKK46144.1 - 0.022 14.0 0.0 0.032 13.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain SRP54 PF00448.22 KKK46144.1 - 0.025 14.2 0.0 0.078 12.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CbiA PF01656.23 KKK46144.1 - 0.026 14.6 0.0 0.078 13.0 0.0 1.8 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Plasmid_parti PF01672.16 KKK46144.1 - 0.061 14.0 7.5 0.084 13.5 3.7 2.5 1 1 1 2 2 2 0 Putative plasmid partition protein AAA_28 PF13521.6 KKK46144.1 - 0.068 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KKK46144.1 - 0.073 12.8 0.3 0.3 10.8 0.0 2.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 KKK46144.1 - 0.085 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1492 PF07374.11 KKK46144.1 - 0.097 12.8 3.6 0.62 10.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) APS_kinase PF01583.20 KKK46144.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase B12-binding PF02310.19 KKK46145.1 - 3.1e-16 59.5 0.3 3.5e-16 59.3 0.3 1.1 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 KKK46145.1 - 0.017 14.1 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain MM_CoA_mutase PF01642.22 KKK46146.1 - 3e-143 478.1 0.0 3.6e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase MM_CoA_mutase PF01642.22 KKK46147.1 - 1.4e-13 50.2 0.0 1.7e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase Imm27 PF15590.6 KKK46147.1 - 0.029 14.1 1.9 0.061 13.1 1.0 1.9 2 0 0 2 2 2 0 Immunity protein 27 Csd3_N PF18059.1 KKK46147.1 - 0.064 13.8 0.3 0.13 12.8 0.2 1.6 1 1 1 2 2 2 0 Csd3 N-terminal PIN PF01850.21 KKK46148.1 - 1e-09 38.9 0.1 1.2e-09 38.7 0.1 1.0 1 0 0 1 1 1 1 PIN domain DUF3895 PF13034.6 KKK46148.1 - 0.087 12.8 0.2 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) PIN_12 PF16289.5 KKK46148.1 - 0.11 13.0 4.6 0.39 11.2 4.4 1.8 1 1 0 1 1 1 0 PIN domain DUF5615 PF18480.1 KKK46148.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) VAPB_antitox PF02697.14 KKK46149.1 - 1.6e-13 51.2 3.9 2e-13 50.9 3.9 1.1 1 0 0 1 1 1 1 Putative antitoxin Imm51 PF15595.6 KKK46149.1 - 0.03 14.3 0.1 0.053 13.5 0.1 1.5 1 1 1 2 2 2 0 Immunity protein 51 DNMT1-RFD PF12047.8 KKK46149.1 - 0.033 14.2 0.2 0.047 13.7 0.2 1.2 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain OS-D PF03392.13 KKK46149.1 - 0.12 12.5 0.3 0.23 11.6 0.2 1.5 1 1 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Acyl-CoA_dh_1 PF00441.24 KKK46150.1 - 1.3e-50 171.5 4.0 1.9e-50 171.0 4.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK46150.1 - 7.7e-36 123.2 0.0 1.7e-35 122.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK46150.1 - 1.3e-26 92.7 0.1 2.2e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK46150.1 - 1.8e-24 86.5 1.4 2.8e-24 85.9 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KKK46150.1 - 0.00099 18.8 0.7 0.016 14.9 0.1 2.4 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.24 KKK46151.1 - 1.9e-50 171.0 2.1 3.2e-50 170.3 2.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KKK46151.1 - 4.2e-32 111.1 0.1 1.3e-31 109.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KKK46151.1 - 7.6e-26 90.1 0.1 1.4e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KKK46151.1 - 2.9e-23 82.6 0.1 4.7e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KKK46151.1 - 6.2e-05 22.8 0.1 0.00022 21.0 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AMP-binding PF00501.28 KKK46153.1 - 9.9e-28 96.9 0.2 1.1e-27 96.7 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KKK46154.1 - 8.2e-43 146.6 0.0 1e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK46154.1 - 3.8e-22 78.0 1.2 6.8e-22 77.1 1.2 1.4 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AcetylCoA_hyd_C PF13336.6 KKK46155.1 - 1.1e-57 194.3 0.0 1.8e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KKK46155.1 - 4.8e-27 95.2 0.0 1.1e-26 94.0 0.0 1.5 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain Acetyltransf_1 PF00583.25 KKK46155.1 - 8.9e-07 29.2 0.1 2.1e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KKK46155.1 - 0.00037 21.2 0.0 0.00067 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KKK46155.1 - 0.0019 18.4 0.5 0.013 15.6 0.2 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KKK46155.1 - 0.0022 17.9 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KKK46155.1 - 0.024 15.1 0.0 0.069 13.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_trans PF01144.23 KKK46155.1 - 0.076 12.4 0.1 8.9 5.6 0.0 2.5 2 0 0 2 2 2 0 Coenzyme A transferase Acetyltransf_CG PF14542.6 KKK46155.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Phage_int_SAM_5 PF13102.6 KKK46156.1 - 0.12 12.8 1.4 0.39 11.1 0.2 2.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain Laminin_G_3 PF13385.6 KKK46156.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily PAP2 PF01569.21 KKK46157.1 - 5.4e-18 65.1 2.6 5.4e-18 65.1 2.6 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KKK46157.1 - 4.3e-08 33.1 6.2 4.3e-08 33.1 6.2 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KKK46157.1 - 0.008 16.7 2.6 0.008 16.7 2.6 3.2 3 1 0 3 3 3 1 PAP2 superfamily C-terminal Cadherin_C_2 PF16492.5 KKK46157.1 - 2.7 8.8 6.6 14 6.5 0.0 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal MARVEL PF01284.23 KKK46157.1 - 4.6 7.3 14.7 6 6.9 10.9 2.9 2 1 0 2 2 2 0 Membrane-associating domain Gtr1_RagA PF04670.12 KKK46158.1 - 2.2e-20 73.0 0.0 4.3e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK46158.1 - 7.3e-20 71.1 0.1 1.4e-19 70.2 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KKK46158.1 - 3.6e-07 29.9 0.0 5.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46158.1 - 6e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KKK46158.1 - 7.2e-07 28.8 0.0 1.8e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KKK46158.1 - 2.5e-05 24.3 0.0 7.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase TFIIB PF00382.19 KKK46159.1 - 8.4e-30 102.6 1.0 4.1e-16 58.8 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat zf-RRN7 PF11781.8 KKK46159.1 - 0.00023 20.8 0.6 0.00043 19.9 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RB_B PF01857.20 KKK46159.1 - 0.0021 18.1 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain A2L_zn_ribbon PF08792.10 KKK46159.1 - 0.02 14.6 2.0 0.036 13.8 2.0 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain Rubredoxin_2 PF18073.1 KKK46159.1 - 0.13 12.0 0.3 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 Rubredoxin metal binding domain Rep_fac-A_C PF08646.10 KKK46159.1 - 0.64 9.8 3.8 12 5.6 0.0 3.0 2 1 1 3 3 3 0 Replication factor-A C terminal domain TPR_2 PF07719.17 KKK46160.1 - 0.0073 16.3 17.7 0.33 11.2 0.4 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK46160.1 - 0.02 14.9 0.3 6 7.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KKK46160.1 - 0.32 10.9 10.7 2.9 7.8 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RNA_pol_A_bac PF01000.26 KKK46161.1 - 0.082 13.3 0.5 0.14 12.5 0.5 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain Transposase_22 PF02994.14 KKK46161.1 - 0.13 12.5 1.7 0.2 11.9 0.2 2.1 1 1 1 2 2 2 0 L1 transposable element RBD-like domain DUF1825 PF08855.10 KKK46161.1 - 0.23 11.4 4.9 0.59 10.1 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1825) Ph1570 PF09638.10 KKK46162.1 - 0.018 14.9 0.5 0.035 14.0 0.5 1.6 1 0 0 1 1 1 0 Ph1570 protein FtsX_ECD PF18075.1 KKK46162.1 - 0.047 14.3 3.6 0.83 10.3 0.0 2.6 2 1 1 3 3 3 0 FtsX extracellular domain UPF0203 PF05254.12 KKK46162.1 - 0.072 13.4 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF2085 PF09858.9 KKK46163.1 - 5.2e-13 49.3 2.1 5.2e-13 49.3 2.1 3.6 3 1 1 4 4 4 1 Predicted membrane protein (DUF2085) Hydrolase_4 PF12146.8 KKK46165.1 - 6.6e-09 35.4 0.0 8.7e-06 25.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK46165.1 - 7.8e-08 32.3 0.1 9.2e-05 22.2 0.1 2.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KKK46165.1 - 1.7e-07 31.3 0.0 2.6e-05 24.2 0.0 2.0 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase UPF0227 PF05728.12 KKK46165.1 - 4.5e-07 30.0 0.1 1.2e-05 25.4 0.0 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 KKK46165.1 - 9.5e-06 25.4 0.0 5e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 KKK46165.1 - 2.3e-05 24.2 0.0 3.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 KKK46165.1 - 0.0012 19.5 0.0 0.0013 19.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 KKK46165.1 - 0.0046 16.6 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 KKK46165.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.13 KKK46165.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase DUF5490 PF17593.2 KKK46165.1 - 0.081 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5490) DP PF08781.10 KKK46165.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor DP MHCassoc_trimer PF08831.10 KKK46165.1 - 0.13 12.3 0.4 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain DZR PF12773.7 KKK46166.1 - 0.0011 18.9 0.2 0.0019 18.2 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-LYAR PF08790.11 KKK46166.1 - 0.0051 16.7 1.5 0.29 11.1 0.2 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Rtf2 PF04641.12 KKK46166.1 - 0.015 14.7 0.4 0.02 14.3 0.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zinc_ribbon_2 PF13240.6 KKK46166.1 - 0.033 13.9 4.2 2.3 8.0 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 KKK46166.1 - 0.035 14.6 2.8 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type FYDLN_acid PF09538.10 KKK46166.1 - 0.059 14.1 0.1 0.094 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 KKK46166.1 - 0.061 13.5 1.6 0.15 12.2 1.3 1.7 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 KKK46166.1 - 0.11 13.4 3.2 0.53 11.3 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 KKK46166.1 - 0.15 11.7 0.4 9.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Nudix_N_2 PF14803.6 KKK46166.1 - 0.2 11.6 1.4 15 5.6 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal zf-C2H2_jaz PF12171.8 KKK46166.1 - 0.23 11.8 4.5 4.3 7.7 0.4 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 KKK46166.1 - 0.24 11.5 2.5 5 7.3 0.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 KKK46166.1 - 0.42 10.4 3.2 0.49 10.2 0.1 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type C1_1 PF00130.22 KKK46166.1 - 0.44 10.5 2.4 7.5 6.5 0.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HE PF16278.5 KKK46166.1 - 0.66 10.5 3.3 0.43 11.1 0.6 1.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TF_Zn_Ribbon PF08271.12 KKK46166.1 - 1.9 8.1 4.8 12 5.5 4.6 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding TyeA PF09059.10 KKK46167.1 - 0.0079 16.3 0.5 2 8.6 0.1 3.3 2 1 1 3 3 3 1 TyeA Zn-ribbon_8 PF09723.10 KKK46167.1 - 0.045 13.9 0.3 0.095 12.8 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KKK46167.1 - 0.062 13.2 0.5 0.099 12.6 0.5 1.3 1 0 0 1 1 1 0 SprT-like zinc ribbon domain MgtE_N PF03448.17 KKK46167.1 - 0.37 11.4 3.9 2.1 9.0 2.6 2.6 1 1 1 2 2 2 0 MgtE intracellular N domain DUF1539 PF07560.11 KKK46167.1 - 0.41 10.7 4.5 0.71 10.0 2.1 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) zinc_ribbon_2 PF13240.6 KKK46167.1 - 0.61 9.9 2.4 5 7.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain UL41A PF17591.2 KKK46167.1 - 0.76 9.9 6.9 11 6.2 0.6 2.7 2 0 0 2 2 2 0 Herpesvirus UL41A DUF872 PF05915.12 KKK46167.1 - 1.9 8.7 9.4 1.4 9.1 0.1 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF3592 PF12158.8 KKK46167.1 - 4.3 7.4 4.4 1.8 8.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) DUF2156 PF09924.9 KKK46171.1 - 5e-13 48.7 0.1 8e-13 48.1 0.1 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) NosD PF05048.13 KKK46172.1 - 7.4e-57 192.4 129.0 3.6e-29 101.7 45.5 3.8 2 1 2 4 4 4 3 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 KKK46172.1 - 2.8e-48 163.7 167.3 5e-17 62.2 46.5 5.5 1 1 5 6 6 6 4 Right handed beta helix region HATPase_c PF02518.26 KKK46173.1 - 2.4e-24 86.0 0.2 5.4e-24 84.8 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK46173.1 - 2.4e-11 43.5 0.2 4.2e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 KKK46173.1 - 9.4e-05 22.3 0.1 0.00041 20.2 0.1 2.2 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KKK46173.1 - 0.00012 22.0 0.0 0.00036 20.5 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KKK46173.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SieB PF14163.6 KKK46173.1 - 8.4 5.9 14.9 5.3 6.5 4.9 2.7 2 1 0 2 2 2 0 Super-infection exclusion protein B DUF2156 PF09924.9 KKK46174.1 - 2.5e-09 36.6 0.0 3.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) DUF2156 PF09924.9 KKK46175.1 - 7.4e-10 38.3 0.0 1.5e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Gp_dh_C PF02800.20 KKK46176.1 - 2.3e-57 193.0 0.0 3.2e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KKK46176.1 - 1.4e-16 60.7 0.0 2.9e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Radical_SAM PF04055.21 KKK46176.1 - 0.033 14.6 0.0 0.056 13.8 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily HEPN PF05168.14 KKK46178.1 - 8.3e-10 38.8 0.1 8.8e-10 38.7 0.1 1.0 1 0 0 1 1 1 1 HEPN domain PAS_9 PF13426.7 KKK46180.1 - 6e-17 61.8 5.2 3e-12 46.7 1.8 3.6 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KKK46180.1 - 5e-15 55.6 0.0 7e-06 26.2 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 KKK46180.1 - 1.4e-12 47.6 0.0 1.9e-08 34.3 0.1 3.5 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.10 KKK46180.1 - 4.6e-11 42.9 0.0 8e-05 22.9 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 KKK46180.1 - 4.2e-07 29.8 0.0 0.00013 21.9 0.0 2.6 2 0 0 2 2 2 1 PAS domain GAF_3 PF13492.6 KKK46180.1 - 0.0023 18.3 0.0 0.0089 16.4 0.0 2.1 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KKK46180.1 - 0.017 15.4 0.1 0.05 13.9 0.1 1.8 1 0 0 1 1 1 0 GAF domain PAS_11 PF14598.6 KKK46180.1 - 0.017 15.2 0.5 0.054 13.6 0.3 2.0 2 0 0 2 2 2 0 PAS domain PAS_7 PF12860.7 KKK46180.1 - 0.018 15.2 0.4 2.6 8.2 0.0 2.8 2 1 0 2 2 2 0 PAS fold GAF PF01590.26 KKK46180.1 - 0.022 15.4 0.0 0.054 14.1 0.0 1.7 1 1 0 1 1 1 0 GAF domain MSA-2c PF12238.8 KKK46180.1 - 0.12 12.4 2.5 0.24 11.4 2.5 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c MEDS PF14417.6 KKK46181.1 - 2.9e-46 157.2 0.0 7.4e-46 155.9 0.0 1.7 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain PAS_4 PF08448.10 KKK46181.1 - 9e-40 135.3 0.0 1.2e-09 38.4 0.0 4.5 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 KKK46181.1 - 2e-32 111.5 7.7 1.7e-12 47.5 0.1 5.2 4 1 1 5 5 5 4 PAS domain PAS PF00989.25 KKK46181.1 - 2.2e-25 88.8 0.0 1.7e-07 31.2 0.0 4.8 4 1 0 4 4 4 4 PAS fold HATPase_c PF02518.26 KKK46181.1 - 3.4e-25 88.7 2.1 4.5e-25 88.3 0.3 2.2 3 0 0 3 3 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KKK46181.1 - 2.2e-16 59.9 0.0 0.00046 20.4 0.0 4.2 4 0 0 4 4 4 3 PAS fold PAS_8 PF13188.7 KKK46181.1 - 2.9e-15 55.9 0.3 2.2e-10 40.3 0.0 4.4 5 0 0 5 5 5 2 PAS domain HisKA PF00512.25 KKK46181.1 - 1.3e-11 44.4 0.3 3.5e-11 43.0 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 KKK46181.1 - 0.00034 20.6 0.0 0.00073 19.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain ZNRF_3_ecto PF18212.1 KKK46181.1 - 0.0018 18.2 1.1 0.84 9.7 0.0 4.4 5 0 0 5 5 5 1 ZNRF-3 Ectodomain PAS_7 PF12860.7 KKK46181.1 - 0.0035 17.5 3.6 0.77 9.9 0.1 5.1 5 1 0 5 5 5 1 PAS fold H_kinase_N PF12282.8 KKK46181.1 - 0.012 15.6 0.0 0.92 9.5 0.0 3.0 1 1 2 3 3 3 0 Signal transduction histidine kinase HATPase_c_3 PF13589.6 KKK46181.1 - 0.018 14.9 0.1 0.06 13.2 0.1 1.9 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MEKHLA PF08670.11 KKK46181.1 - 0.035 14.0 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 MEKHLA domain HATPase_c_5 PF14501.6 KKK46181.1 - 0.054 13.4 5.9 0.036 14.0 0.7 3.4 3 1 0 3 3 2 0 GHKL domain LPD22 PF18834.1 KKK46181.1 - 0.12 12.6 0.4 9.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 ATP-synt_E PF05680.12 KKK46181.1 - 0.45 10.9 12.7 5.4 7.4 0.4 3.8 4 0 0 4 4 3 0 ATP synthase E chain TPP_enzyme_C PF02775.21 KKK46182.1 - 8.2e-23 80.9 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 KKK46182.1 - 1.7e-05 24.9 0.3 3.4e-05 23.9 0.3 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal POR_N PF01855.19 KKK46183.1 - 1.6e-47 162.2 0.1 2.2e-47 161.7 0.1 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 KKK46183.1 - 7.2e-18 65.3 0.1 1.8e-17 64.0 0.1 1.7 1 1 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_N PF02776.18 KKK46183.1 - 6.3e-05 22.7 0.4 0.00014 21.6 0.4 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain zinc_ribbon_15 PF17032.5 KKK46184.1 - 0.0026 18.5 6.0 0.003 18.3 6.0 1.4 1 1 0 1 1 1 1 zinc-ribbon family DUF4471 PF14740.6 KKK46184.1 - 0.003 16.9 1.1 0.0031 16.8 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DZR PF12773.7 KKK46184.1 - 0.0069 16.4 0.4 0.0085 16.1 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 KKK46184.1 - 0.0084 16.2 1.2 0.016 15.3 1.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 TusA PF01206.17 KKK46184.1 - 0.017 15.0 0.3 0.029 14.2 0.3 1.6 1 0 0 1 1 1 0 Sulfurtransferase TusA zf-ribbon_3 PF13248.6 KKK46184.1 - 0.037 13.4 6.0 0.099 12.1 6.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain TackOD1 PF18551.1 KKK46184.1 - 0.039 13.6 5.8 0.13 11.9 5.9 1.6 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 Auto_anti-p27 PF06677.12 KKK46184.1 - 0.043 14.0 4.2 0.12 12.6 4.3 1.7 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_3 PF13920.6 KKK46184.1 - 0.054 13.4 1.9 0.089 12.7 1.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YwqJ-deaminase PF14431.6 KKK46184.1 - 0.055 13.6 0.2 0.055 13.6 0.2 1.6 1 1 1 2 2 2 0 YwqJ-like deaminase DUF1610 PF07754.11 KKK46184.1 - 0.057 13.4 2.4 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-RING_7 PF02591.15 KKK46184.1 - 0.062 13.5 1.9 3.8 7.8 0.0 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain DUF35_N PF12172.8 KKK46184.1 - 0.29 11.1 1.8 2.9 7.8 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ACC PF17848.1 KKK46184.1 - 0.64 10.2 6.7 2 8.6 0.1 2.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_2 PF13240.6 KKK46184.1 - 2 8.3 6.5 8 6.3 6.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Sec62 PF03839.16 KKK46184.1 - 2.2 7.8 7.0 2.4 7.6 7.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 vWA-TerF-like PF10138.9 KKK46185.1 - 0.067 13.3 0.1 0.073 13.2 0.1 1.1 1 0 0 1 1 1 0 vWA found in TerF C terminus RNA_pol_Rpc34 PF05158.12 KKK46188.1 - 0.026 13.9 0.1 0.033 13.6 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Ost5 PF05251.12 KKK46189.1 - 3.6e-08 33.6 5.3 3.9e-08 33.4 5.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 UbiA PF01040.18 KKK46189.1 - 0.019 14.2 7.6 0.022 14.1 7.6 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF5453 PF17534.2 KKK46189.1 - 0.022 14.7 3.6 0.028 14.4 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5453) LHC PF00556.20 KKK46189.1 - 0.036 14.3 8.2 0.65 10.3 0.7 2.2 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit PsbN PF02468.15 KKK46189.1 - 1.1 9.2 4.2 0.6 10.0 1.5 1.9 1 1 1 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF202 PF02656.15 KKK46189.1 - 3 8.4 7.7 3.9 8.0 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF4191 PF13829.6 KKK46189.1 - 4.1 6.7 4.7 4.2 6.6 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4131 PF13567.6 KKK46189.1 - 7.2 6.2 7.8 8.6 6.0 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RNA_pol_Rpb2_6 PF00562.28 KKK46191.1 - 2.1e-122 409.0 0.0 2.9e-122 408.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KKK46191.1 - 1.1e-55 188.3 0.1 1.7e-55 187.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KKK46191.1 - 1.5e-35 122.5 0.3 3.1e-35 121.5 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KKK46191.1 - 1.6e-29 102.2 0.1 3.1e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KKK46191.1 - 8.8e-25 86.7 0.0 1.9e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KKK46191.1 - 5e-22 78.0 0.3 1.1e-21 76.8 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KKK46191.1 - 1.2e-12 48.2 1.3 4.6e-12 46.3 1.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NOB1_Zn_bind PF08772.11 KKK46191.1 - 0.0037 17.4 0.2 0.0084 16.3 0.2 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like RNA_pol_Rpb2_45 PF10385.9 KKK46191.1 - 0.1 12.9 0.1 0.56 10.5 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Auto_anti-p27 PF06677.12 KKK46191.1 - 0.33 11.1 1.7 0.8 9.9 1.7 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-NADH-PPase PF09297.11 KKK46191.1 - 0.34 10.6 1.1 2.1 8.1 0.0 2.6 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain RNA_pol_Rpb5_C PF01191.19 KKK46192.1 - 1.2e-24 85.9 0.2 1.4e-24 85.8 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain MTS PF05175.14 KKK46193.1 - 1e-34 119.6 0.0 1.2e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KKK46193.1 - 2.4e-07 30.6 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK46193.1 - 1.2e-05 24.8 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KKK46193.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 KKK46193.1 - 1.8e-05 24.6 0.1 9.2e-05 22.3 0.0 1.8 1 1 1 2 2 2 1 Met-10+ like-protein Methyltransf_18 PF12847.7 KKK46193.1 - 9.5e-05 22.4 0.0 0.00025 21.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK46193.1 - 0.00023 21.8 0.0 0.00033 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK46193.1 - 0.00031 20.6 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK46193.1 - 0.00035 21.2 0.0 0.00065 20.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KKK46193.1 - 0.0008 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KKK46193.1 - 0.002 17.8 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 KKK46193.1 - 0.0044 16.1 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase GidB PF02527.15 KKK46193.1 - 0.069 12.5 0.3 0.24 10.7 0.2 1.9 2 1 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 KKK46193.1 - 0.1 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KKK46193.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.18 KKK46193.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CHS5_N PF16892.5 KKK46193.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Chitin biosynthesis protein CHS5 N-terminus Androgen_recep PF02166.16 KKK46193.1 - 0.31 9.8 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Androgen receptor TruB_N PF01509.18 KKK46194.1 - 1.1e-22 81.0 1.2 1.7e-18 67.4 1.2 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.12 KKK46194.1 - 1.2e-19 70.1 0.1 3e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 KKK46194.1 - 8.7e-19 67.4 0.0 2.3e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KKK46194.1 - 9.2e-13 48.0 0.2 2.5e-12 46.6 0.1 1.8 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 KKK46194.1 - 0.025 14.9 0.1 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 UPF0113 PUA domain Ribosomal_L2_C PF03947.18 KKK46195.1 - 5.2e-40 136.6 0.2 7.2e-40 136.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KKK46195.1 - 6.9e-13 48.4 0.0 4.1e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Asparaginase PF00710.20 KKK46196.1 - 2.4e-55 187.1 0.1 3.9e-55 186.4 0.1 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KKK46196.1 - 5.3e-31 107.2 0.0 1.4e-30 105.8 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GatD_N PF18195.1 KKK46196.1 - 2.3e-19 68.5 3.3 5.6e-19 67.2 3.3 1.7 1 0 0 1 1 1 1 GatD N-terminal domain GatB_N PF02934.15 KKK46197.1 - 7.1e-59 199.4 0.0 1.1e-58 198.9 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KKK46197.1 - 1.4e-15 57.5 4.9 1.4e-15 57.5 4.9 2.0 2 0 0 2 2 2 1 GatB domain YqeY PF09424.10 KKK46197.1 - 4.6e-07 30.0 2.7 4.6e-07 30.0 2.7 1.9 2 0 0 2 2 2 1 Yqey-like protein GAD PF02938.14 KKK46197.1 - 3.3e-06 27.3 1.8 4.6e-06 26.8 0.2 2.1 2 0 0 2 2 2 1 GAD domain PNK3P PF08645.11 KKK46201.1 - 0.049 13.3 0.5 0.066 12.9 0.5 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase ComA PF02679.15 KKK46201.1 - 0.073 12.5 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) LepB_GAP_C PF18227.1 KKK46202.1 - 0.00084 19.8 0.0 0.00088 19.7 0.0 1.0 1 0 0 1 1 1 1 LepB GAP domain C-terminal subdomain Peptidase_S58 PF03576.14 KKK46202.1 - 0.08 12.4 0.0 0.082 12.4 0.0 1.0 1 0 0 1 1 1 0 Peptidase family S58 Mut7-C PF01927.16 KKK46203.1 - 0.076 13.1 0.7 0.11 12.6 0.7 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain EZH2_WD-Binding PF11616.8 KKK46203.1 - 0.24 11.5 1.5 0.29 11.2 0.3 1.8 2 0 0 2 2 2 0 WD repeat binding protein EZH2 Radical_SAM_C PF16199.5 KKK46205.1 - 4.4e-28 97.1 0.0 9.3e-28 96.1 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KKK46205.1 - 5.9e-21 75.6 0.1 1.2e-20 74.6 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KKK46205.1 - 0.011 16.0 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK46205.1 - 0.015 15.2 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HTH_39 PF14090.6 KKK46205.1 - 0.06 13.1 0.2 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain DHODB_Fe-S_bind PF10418.9 KKK46206.1 - 1.6e-09 37.4 3.2 2.7e-09 36.7 3.2 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FAD_binding_6 PF00970.24 KKK46206.1 - 5.4e-05 23.5 0.0 0.00014 22.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain DHO_dh PF01180.21 KKK46207.1 - 3.2e-60 203.9 4.0 3.6e-60 203.7 4.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 KKK46207.1 - 1.1e-09 37.9 0.1 7.9e-06 25.2 0.0 2.9 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 KKK46207.1 - 7.9e-07 28.8 0.7 2.5e-06 27.1 0.7 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KKK46207.1 - 0.00035 19.7 0.7 0.001 18.1 0.1 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KKK46207.1 - 0.00054 19.5 0.4 0.0014 18.2 0.1 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 KKK46207.1 - 0.00077 18.6 0.2 0.0052 15.8 0.2 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.17 KKK46207.1 - 0.0047 16.4 0.3 1 8.7 0.0 2.3 2 0 0 2 2 2 2 PcrB family G3P_antiterm PF04309.12 KKK46207.1 - 0.033 13.6 0.3 2.3 7.6 0.0 3.5 4 0 0 4 4 4 0 Glycerol-3-phosphate responsive antiterminator FtsL PF04999.13 KKK46210.1 - 0.0092 16.0 1.0 0.35 10.9 0.0 3.4 3 0 0 3 3 3 1 Cell division protein FtsL DUF4279 PF14106.6 KKK46210.1 - 0.032 14.4 0.4 1.1 9.5 0.2 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4279) HTH_24 PF13412.6 KKK46210.1 - 0.033 13.8 1.7 73 3.0 0.0 5.3 7 0 0 7 7 7 0 Winged helix-turn-helix DNA-binding Tox-HNH-HHH PF15637.6 KKK46210.1 - 0.06 13.5 1.7 18 5.6 0.0 4.0 3 1 1 4 4 4 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif KI67R PF08065.12 KKK46210.1 - 0.086 13.4 0.1 5 7.7 0.0 2.9 2 0 0 2 2 2 0 KI67R (NUC007) repeat HTH_3 PF01381.22 KKK46210.1 - 0.1 12.7 3.0 41 4.3 0.0 4.6 4 0 0 4 4 4 0 Helix-turn-helix HTH_10 PF04967.12 KKK46210.1 - 0.5 10.2 5.6 2.9 7.8 0.0 4.4 5 0 0 5 5 5 0 HTH DNA binding domain Xpo1 PF08389.12 KKK46210.1 - 1 9.4 5.9 7.4 6.6 0.0 4.2 4 1 0 4 4 4 0 Exportin 1-like protein CBP_BcsG PF11658.8 KKK46213.1 - 0.89 7.9 5.1 0.88 7.9 5.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG PGG PF13962.6 KKK46213.1 - 3.5 7.5 9.4 0.54 10.1 5.2 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF2070 PF09843.9 KKK46213.1 - 4.3 5.5 14.2 4.8 5.3 14.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TLP1_add_C PF18313.1 KKK46214.1 - 2.1e-12 46.8 0.0 3.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_C PF02803.18 KKK46214.1 - 0.0034 17.0 0.0 0.0085 15.7 0.0 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thioredoxin PF00085.20 KKK46215.1 - 4e-26 91.0 0.0 5e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK46215.1 - 4.6e-08 33.3 0.7 8e-07 29.3 0.1 2.3 2 1 1 3 3 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KKK46215.1 - 8.6e-07 29.4 0.0 2.4e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KKK46215.1 - 2e-06 27.4 0.0 3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KKK46215.1 - 5.4e-06 26.3 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 KKK46215.1 - 3.6e-05 23.7 0.0 4.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 KKK46215.1 - 4.8e-05 23.1 0.0 5.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 KKK46215.1 - 0.00036 20.7 0.1 0.00061 19.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KKK46215.1 - 0.00064 19.5 0.1 0.0011 18.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KKK46215.1 - 0.0075 16.2 0.0 0.01 15.8 0.0 1.3 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KKK46215.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_6 PF13848.6 KKK46215.1 - 0.052 13.5 0.0 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like domain Pyr_redox_2 PF07992.14 KKK46217.1 - 4.4e-06 26.1 0.0 4.3e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KKK46217.1 - 6.2e-06 26.0 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KKK46217.1 - 0.00089 18.1 0.0 0.28 9.8 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KKK46217.1 - 0.0037 16.6 0.4 0.037 13.3 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KKK46217.1 - 0.0062 16.5 0.0 0.88 9.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KKK46217.1 - 0.024 14.8 1.4 0.052 13.8 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF4180 PF13788.6 KKK46217.1 - 0.038 13.9 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4180) GIDA PF01134.22 KKK46217.1 - 0.039 13.0 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KKK46217.1 - 0.13 11.5 0.0 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NifU PF01106.17 KKK46219.1 - 8.7e-27 93.1 0.2 9.6e-27 92.9 0.2 1.0 1 0 0 1 1 1 1 NifU-like domain FeS_assembly_P PF01883.19 KKK46219.1 - 0.027 14.7 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein HydF_tetramer PF18133.1 KKK46219.1 - 0.035 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain CdiA_C PF18451.1 KKK46219.1 - 0.047 13.9 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain LIDHydrolase PF10230.9 KKK46219.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2207 PF09972.9 KKK46220.1 - 0.025 13.4 2.0 0.045 12.5 2.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4181 PF13789.6 KKK46220.1 - 0.034 14.4 0.2 0.072 13.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Succ_CoA_lig PF13607.6 KKK46221.1 - 3.7e-17 62.4 0.1 2e-15 56.8 0.0 3.0 3 1 1 4 4 4 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KKK46221.1 - 2.1e-14 54.0 0.0 9.2e-12 45.5 0.0 3.2 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 KKK46221.1 - 0.036 14.7 0.0 0.13 13.0 0.0 2.1 1 0 0 1 1 1 0 CoA binding domain Ribosomal_L16 PF00252.18 KKK46222.1 - 6.3e-10 39.2 0.0 8.3e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Thioredoxin PF00085.20 KKK46223.1 - 3.7e-22 78.3 0.0 5.1e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KKK46223.1 - 4.5e-08 33.3 0.2 2e-05 24.8 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KKK46223.1 - 1.5e-05 25.1 0.0 2.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KKK46223.1 - 1.6e-05 25.3 0.0 4.4e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KKK46223.1 - 0.00013 21.8 0.1 0.00032 20.6 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KKK46223.1 - 0.00059 19.6 0.0 0.0029 17.3 0.0 1.9 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 KKK46223.1 - 0.0021 17.5 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF953 PF06110.11 KKK46223.1 - 0.0077 15.8 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) HyaE PF07449.11 KKK46223.1 - 0.014 15.3 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KKK46223.1 - 0.041 13.6 0.1 0.062 13.1 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_6 PF13848.6 KKK46223.1 - 0.056 13.4 0.2 0.088 12.7 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Radical_SAM PF04055.21 KKK46224.1 - 1.2e-10 42.0 0.1 2.6e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_hydro_38N PF01074.22 KKK46224.1 - 0.0001 21.8 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Na_Ca_ex_C PF16494.5 KKK46224.1 - 0.012 16.0 0.6 0.021 15.3 0.6 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Fer4_14 PF13394.6 KKK46224.1 - 0.025 14.7 0.9 0.052 13.7 0.9 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain DeoC PF01791.9 KKK46224.1 - 0.035 13.7 0.1 0.084 12.5 0.1 1.5 2 0 0 2 2 2 0 DeoC/LacD family aldolase Ribul_P_3_epim PF00834.19 KKK46224.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family adh_short PF00106.25 KKK46225.1 - 1.6e-43 148.5 0.2 1.9e-43 148.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK46225.1 - 2.1e-33 115.8 0.0 3.5e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK46225.1 - 1.5e-12 47.8 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Alba PF01918.21 KKK46225.1 - 0.008 16.0 0.3 0.025 14.4 0.3 1.8 1 0 0 1 1 1 1 Alba Sacchrp_dh_NADP PF03435.18 KKK46225.1 - 0.026 14.8 0.3 0.052 13.8 0.3 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LUD_dom PF02589.15 KKK46226.1 - 1e-29 103.6 2.1 6.3e-29 101.0 2.1 2.0 1 1 0 1 1 1 1 LUD domain Fer4_8 PF13183.6 KKK46226.1 - 9.9e-08 32.3 1.4 9.9e-08 32.3 1.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46226.1 - 0.00018 22.0 4.7 0.00018 22.0 4.7 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46226.1 - 0.00037 20.6 6.2 0.0028 17.8 6.6 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46226.1 - 0.00046 20.2 10.2 0.0072 16.4 10.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46226.1 - 0.00087 19.8 4.4 0.00087 19.8 4.4 2.7 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46226.1 - 0.0023 18.8 6.5 0.52 11.3 1.1 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KKK46226.1 - 0.0035 17.3 12.0 0.21 11.7 1.6 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK46226.1 - 0.027 14.6 14.1 0.31 11.2 13.1 2.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK46226.1 - 0.034 15.0 8.0 0.45 11.4 0.3 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain LBP_M PF17385.2 KKK46226.1 - 0.061 12.8 0.5 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase central domain Fer4_20 PF14691.6 KKK46226.1 - 0.31 10.8 4.1 0.82 9.5 0.5 2.4 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_6 PF12837.7 KKK46226.1 - 0.51 10.5 10.5 3.6 7.8 2.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 KKK46226.1 - 0.52 10.5 6.7 0.71 10.1 0.2 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK46226.1 - 4.9 8.3 16.2 0.68 11.0 5.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain CCG PF02754.16 KKK46227.1 - 1.1e-12 48.0 0.1 1.6e-12 47.5 0.1 1.3 1 0 0 1 1 1 1 Cysteine-rich domain DSBA PF01323.20 KKK46227.1 - 0.16 11.7 0.0 0.58 9.9 0.0 1.8 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF4281 PF14108.6 KKK46232.1 - 0.0087 16.4 0.5 0.01 16.2 0.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4281) SpoIIM PF01944.17 KKK46232.1 - 0.041 13.9 7.9 0.074 13.1 7.9 1.4 1 1 0 1 1 1 0 Stage II sporulation protein M DUF2207 PF09972.9 KKK46232.1 - 0.35 9.6 3.9 0.39 9.4 3.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FtsX PF02687.21 KKK46232.1 - 0.79 10.2 9.8 1.6 9.3 0.2 2.1 2 0 0 2 2 2 0 FtsX-like permease family DHHC PF01529.20 KKK46232.1 - 1 9.5 3.5 1.4 9.1 3.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Sigma_reg_N PF13800.6 KKK46232.1 - 1.1 9.6 8.0 0.58 10.5 2.2 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SP_C-Propep PF08999.10 KKK46232.1 - 1.4 8.8 4.4 7.3 6.5 0.1 2.2 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Wzz PF02706.15 KKK46232.1 - 7.5 6.9 9.1 1 9.7 0.6 2.2 2 0 0 2 2 2 0 Chain length determinant protein Thioredoxin PF00085.20 KKK46236.1 - 1.7e-17 63.3 0.0 2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KKK46236.1 - 0.00021 21.7 0.1 0.022 15.2 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 KKK46236.1 - 0.00029 21.2 0.0 0.00046 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.6 KKK46236.1 - 0.00053 19.7 0.0 0.00067 19.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KKK46236.1 - 0.0025 16.8 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Phosducin HyaE PF07449.11 KKK46236.1 - 0.003 17.5 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KKK46236.1 - 0.0061 16.9 0.0 1.6 9.1 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 KKK46236.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin Fer4_8 PF13183.6 KKK46237.1 - 7e-09 36.0 6.3 1.6e-08 34.8 6.3 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46237.1 - 2.4e-07 31.2 4.1 4.4e-07 30.3 4.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46237.1 - 2.5e-07 31.5 5.1 5.3e-07 30.5 5.1 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KKK46237.1 - 5.1e-06 26.5 7.5 1.3e-05 25.3 7.5 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46237.1 - 1.1e-05 25.9 5.7 2.8e-05 24.6 5.7 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46237.1 - 0.00016 21.8 11.3 0.0027 17.8 12.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK46237.1 - 0.0033 17.5 8.0 0.29 11.3 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK46237.1 - 0.0056 16.9 1.9 0.36 11.0 0.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 KKK46237.1 - 0.23 12.3 5.9 2.7 8.9 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46237.1 - 2.4 8.1 16.4 4.8 7.2 3.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain TIM PF00121.18 KKK46238.1 - 4.5e-92 307.8 0.0 5.1e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DIL PF01843.19 KKK46238.1 - 0.04 14.2 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 DIL domain PEP_hydrolase PF09370.10 KKK46238.1 - 0.092 12.0 0.1 0.36 10.0 0.1 1.8 1 1 1 2 2 2 0 Phosphoenolpyruvate hydrolase-like DNA_pol3_beta_2 PF02767.16 KKK46239.1 - 0.092 13.0 0.4 0.18 12.0 0.2 1.5 2 0 0 2 2 2 0 DNA polymerase III beta subunit, central domain Anticodon_1 PF08264.13 KKK46240.1 - 2.8e-18 66.3 3.8 2.8e-18 66.3 3.8 2.3 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 KKK46240.1 - 3.4e-07 28.9 0.3 6.5e-07 28.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKK46240.1 - 0.00044 19.1 0.0 0.00087 18.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (M) zf-C2HC5 PF06221.13 KKK46240.1 - 0.044 13.8 0.6 0.081 12.9 0.6 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF327 PF03885.13 KKK46240.1 - 0.83 9.6 12.4 0.44 10.5 7.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Epimerase PF01370.21 KKK46244.1 - 2.1e-19 70.0 0.1 4.4e-17 62.3 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KKK46244.1 - 3.1e-07 30.1 0.3 1.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KKK46244.1 - 3.4e-05 23.1 0.0 0.0038 16.4 0.0 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 KKK46244.1 - 0.0092 15.2 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KKK46244.1 - 0.02 14.4 0.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Thia_YuaJ PF09515.10 KKK46245.1 - 0.00014 22.0 2.1 0.00022 21.3 2.1 1.3 1 0 0 1 1 1 1 Thiamine transporter protein (Thia_YuaJ) EII-Sor PF03609.14 KKK46245.1 - 0.0015 18.0 3.1 0.0019 17.6 0.1 1.9 1 1 1 2 2 2 1 PTS system sorbose-specific iic component DUF92 PF01940.16 KKK46245.1 - 0.0029 17.1 0.2 0.0042 16.6 0.2 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 H_PPase PF03030.16 KKK46245.1 - 0.0049 15.6 0.2 0.0053 15.4 0.2 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Hpre_diP_synt_I PF07456.11 KKK46245.1 - 0.024 14.6 4.0 0.031 14.3 4.0 1.1 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I Phage_holin_2_4 PF16082.5 KKK46245.1 - 0.047 13.4 2.2 0.049 13.4 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like SieB PF14163.6 KKK46245.1 - 0.13 11.8 1.2 0.2 11.1 1.2 1.4 1 1 0 1 1 1 0 Super-infection exclusion protein B Phage_holin_2_3 PF16080.5 KKK46245.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.6 2 1 1 3 3 3 0 Bacteriophage holin family HP1 Phage_holin_2_1 PF04971.12 KKK46245.1 - 0.16 12.0 0.7 0.16 12.0 0.7 2.2 1 1 0 2 2 2 0 Bacteriophage P21 holin S SNARE_assoc PF09335.11 KKK46245.1 - 0.3 11.6 5.1 1.8 9.1 4.2 2.3 1 1 0 1 1 1 0 SNARE associated Golgi protein UPF0154 PF03672.13 KKK46245.1 - 0.42 10.7 4.4 2 8.5 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF1043 PF06295.12 KKK46245.1 - 0.61 10.1 2.9 0.91 9.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Romo1 PF10247.9 KKK46245.1 - 0.83 10.1 6.4 4.8 7.6 0.1 2.6 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Sm_multidrug_ex PF06695.11 KKK46245.1 - 0.97 10.1 5.7 0.55 10.9 0.4 2.5 1 1 2 3 3 3 0 Putative small multi-drug export protein YtxH PF12732.7 KKK46245.1 - 1.3 9.6 0.1 1.3 9.6 0.1 2.3 3 0 0 3 3 3 0 YtxH-like protein DUF2897 PF11446.8 KKK46245.1 - 5.1 7.0 7.2 4.4 7.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2897) ABC_tran PF00005.27 KKK46246.1 - 1.5e-31 109.7 0.0 4.2e-31 108.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter TOBE_2 PF08402.10 KKK46246.1 - 2e-10 40.7 0.0 5.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 TOBE domain OB_MalK PF17912.1 KKK46246.1 - 3.3e-08 34.2 0.4 9.2e-08 32.8 0.4 1.8 1 0 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 KKK46246.1 - 1.9e-05 24.6 0.0 0.2 11.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KKK46246.1 - 3.7e-05 23.3 0.1 0.0001 21.9 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain TOBE PF03459.17 KKK46246.1 - 5.4e-05 23.4 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 TOBE domain Rad17 PF03215.15 KKK46246.1 - 0.0011 18.9 0.1 0.002 18.1 0.1 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain CbiA PF01656.23 KKK46246.1 - 0.0017 18.4 0.0 0.0051 16.9 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 KKK46246.1 - 0.0063 16.9 0.2 0.026 14.9 0.2 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KKK46246.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KKK46246.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KKK46246.1 - 0.033 14.6 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 KKK46246.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KKK46246.1 - 0.055 13.0 0.3 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KKK46246.1 - 0.057 13.9 0.9 0.13 12.7 0.7 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KKK46246.1 - 0.063 13.7 0.0 0.86 10.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KKK46246.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KKK46246.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KKK46246.1 - 0.12 12.6 0.2 0.33 11.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 KKK46247.1 - 2.4e-15 56.8 15.9 2.4e-15 56.8 15.9 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 KKK46248.1 - 1.1e-18 67.7 21.5 1.1e-18 67.7 21.5 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Glyoxalase PF00903.25 KKK46252.1 - 2.1e-11 44.1 0.0 2.4e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KKK46252.1 - 1.9e-08 34.5 0.0 2.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PepSY_2 PF13670.6 KKK46252.1 - 0.024 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain EutC PF05985.11 KKK46252.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) NikR_C PF08753.11 KKK46254.1 - 4.9e-15 55.5 0.9 4.9e-15 55.5 0.9 2.6 1 1 1 2 2 2 1 NikR C terminal nickel binding domain RHH_1 PF01402.21 KKK46254.1 - 2.5e-06 27.2 0.0 5.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family ADIP PF11559.8 KKK46254.1 - 0.099 12.7 0.8 0.33 11.0 0.5 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Oxidored_FMN PF00724.20 KKK46255.1 - 2.7e-60 204.4 0.0 3.5e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GHMP_kinases_N PF00288.26 KKK46257.1 - 2.9e-15 56.2 0.1 5.2e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KKK46258.1 - 7.6e-05 23.0 0.1 7.9e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 GHMP kinases C terminal Mon1 PF03164.14 KKK46259.1 - 0.00024 20.3 4.2 0.00024 20.3 4.2 1.9 1 1 0 2 2 2 1 Trafficking protein Mon1 Clat_adaptor_s PF01217.20 KKK46259.1 - 0.0007 19.5 6.4 0.0007 19.5 6.4 2.3 1 1 0 2 2 2 1 Clathrin adaptor complex small chain DUF957 PF06117.11 KKK46259.1 - 0.036 13.6 0.6 0.078 12.6 0.6 1.5 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) DDRGK PF09756.9 KKK46259.1 - 0.042 13.5 1.5 0.046 13.3 0.2 1.7 2 0 0 2 2 2 0 DDRGK domain Rubrerythrin PF02915.17 KKK46260.1 - 6.3e-25 88.2 13.9 7.8e-24 84.6 13.9 2.0 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 KKK46260.1 - 0.003 17.5 6.4 0.033 14.1 6.3 2.2 1 1 0 1 1 1 1 Ferritin-like domain Zn-C2H2_12 PF18112.1 KKK46260.1 - 0.045 14.2 2.0 7.5 7.1 0.1 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DUF2043 PF09740.9 KKK46260.1 - 0.046 14.4 0.2 0.12 13.1 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2043) RecR PF02132.15 KKK46260.1 - 0.049 13.2 0.7 0.12 12.0 0.7 1.7 1 0 0 1 1 1 0 RecR protein Zn-ribbon_8 PF09723.10 KKK46260.1 - 0.054 13.6 4.0 1.2 9.3 0.4 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-RRN7 PF11781.8 KKK46260.1 - 0.082 12.6 1.3 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PhoU PF01895.19 KKK46260.1 - 0.13 12.7 0.4 0.42 11.1 0.1 1.8 2 0 0 2 2 2 0 PhoU domain TF_Zn_Ribbon PF08271.12 KKK46260.1 - 0.21 11.1 1.5 12 5.5 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 KKK46260.1 - 0.35 10.8 3.1 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 KKK46260.1 - 0.37 10.6 2.6 12 5.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK46260.1 - 0.74 9.3 4.5 3 7.4 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2960 PF11173.8 KKK46260.1 - 1 9.8 6.0 2.3 8.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) Rubredoxin PF00301.20 KKK46260.1 - 1.6 8.8 5.7 4.2 7.5 0.5 2.4 1 1 1 2 2 2 0 Rubredoxin Rad50_zn_hook PF04423.14 KKK46260.1 - 2 8.3 6.4 18 5.2 1.0 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif DNA_ligase_ZBD PF03119.16 KKK46260.1 - 2.4 8.3 8.3 7.1 6.7 1.2 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Radical_SAM PF04055.21 KKK46261.1 - 3.9e-14 53.4 0.0 7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DNA_PPF PF02916.15 KKK46261.1 - 0.74 10.2 3.8 11 6.4 0.2 3.6 2 1 2 4 4 4 0 DNA polymerase processivity factor SIR2 PF02146.17 KKK46262.1 - 2.2e-49 167.8 0.0 2.7e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family NOA36 PF06524.12 KKK46262.1 - 0.0038 16.6 0.7 0.0061 15.9 0.7 1.2 1 0 0 1 1 1 1 NOA36 protein NTP_transferase PF00483.23 KKK46264.1 - 1.8e-44 152.2 0.0 2.3e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KKK46264.1 - 9.8e-20 69.5 20.1 8.1e-09 34.9 0.4 4.9 3 1 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KKK46264.1 - 1.1e-11 45.3 0.0 1.6e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KKK46264.1 - 1.5e-09 37.5 16.2 7e-07 28.9 0.1 4.5 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 KKK46264.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 KKK46264.1 - 0.096 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Glyco_tranf_2_3 PF13641.6 KKK46264.1 - 0.18 11.6 0.0 0.26 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Ribosomal_S3Ae PF01015.18 KKK46265.1 - 2.2e-47 161.3 4.1 3.1e-47 160.8 4.1 1.2 1 0 0 1 1 1 1 Ribosomal S3Ae family Ribosomal_S13_N PF08069.12 KKK46266.1 - 7.6e-27 93.1 0.6 1.6e-26 92.1 0.6 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KKK46266.1 - 2.6e-12 46.8 0.9 4e-12 46.2 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ham1p_like PF01725.16 KKK46267.1 - 1e-43 149.5 0.0 1.2e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ribonucleas_3_3 PF14622.6 KKK46268.1 - 8.6e-16 58.3 0.0 1.3e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KKK46268.1 - 9e-14 52.0 0.0 2.5e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain GlutR_dimer PF00745.20 KKK46269.1 - 0.028 14.8 3.3 0.066 13.7 0.8 2.3 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Lyase_1 PF00206.20 KKK46269.1 - 0.11 11.9 2.3 0.12 11.7 2.3 1.0 1 0 0 1 1 1 0 Lyase DUF3500 PF12006.8 KKK46269.1 - 0.12 11.9 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) 3H PF02829.14 KKK46269.1 - 0.13 12.6 4.8 0.074 13.4 2.2 2.0 2 1 0 2 2 2 0 3H domain RMMBL PF07521.12 KKK46269.1 - 0.22 11.5 1.2 12 5.9 0.2 2.5 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain DUF2115 PF09888.9 KKK46269.1 - 0.3 11.6 3.5 0.52 10.8 3.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) SLS PF14611.6 KKK46269.1 - 0.32 10.8 6.9 0.39 10.5 6.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator RNA_POL_M_15KD PF02150.16 KKK46271.1 - 9.7e-08 31.8 3.4 1.3e-07 31.3 3.4 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit zinc-ribbons_6 PF07191.12 KKK46271.1 - 0.00055 19.9 0.3 0.00091 19.2 0.3 1.4 1 0 0 1 1 1 1 zinc-ribbons DpnI PF06044.12 KKK46271.1 - 0.0019 17.9 0.5 0.0023 17.6 0.5 1.2 1 0 0 1 1 1 1 Dam-replacing family Auto_anti-p27 PF06677.12 KKK46271.1 - 0.0085 16.2 1.9 0.012 15.7 1.9 1.2 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KKK46271.1 - 0.02 14.9 0.5 0.03 14.3 0.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 KKK46271.1 - 0.023 14.9 1.0 0.042 14.1 1.0 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 KKK46271.1 - 0.055 13.8 1.3 0.055 13.8 1.3 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.6 KKK46271.1 - 0.2 11.4 2.7 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GDPD PF03009.17 KKK46272.1 - 7e-42 143.9 0.0 3.7e-41 141.6 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KKK46272.1 - 1.6e-07 31.5 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Hexapep PF00132.24 KKK46273.1 - 0.0072 16.0 0.2 0.43 10.4 0.0 3.0 2 2 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) RseC_MucC PF04246.12 KKK46273.1 - 0.52 10.3 4.3 0.86 9.6 4.3 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SpoU_methylase PF00588.19 KKK46277.1 - 0.15 12.2 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 SpoU rRNA Methylase family TetR_N PF00440.23 KKK46280.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Rad51 PF08423.11 KKK46282.1 - 7.5e-11 41.8 0.0 8.1e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 Rad51 AMP-binding PF00501.28 KKK46283.1 - 4.7e-94 315.4 0.0 6e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK46283.1 - 1.4e-12 48.4 0.4 3.3e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Gtr1_RagA PF04670.12 KKK46284.1 - 2.7e-15 56.3 0.6 3.2e-15 56.1 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KKK46284.1 - 4.9e-15 55.4 0.1 5.6e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KKK46284.1 - 7.2e-09 35.3 0.1 8.6e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK46284.1 - 1.8e-08 34.6 0.0 2.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK46284.1 - 2.2e-06 27.7 0.0 3.3e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KKK46284.1 - 1.7e-05 24.4 0.3 2.4e-05 24.0 0.3 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KKK46284.1 - 0.00061 19.1 2.3 0.29 10.3 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit DUF4479 PF14794.6 KKK46284.1 - 0.045 13.6 0.2 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) SRP54 PF00448.22 KKK46284.1 - 0.15 11.7 0.2 8.3 6.0 0.0 2.2 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KKK46284.1 - 0.18 12.3 0.5 0.34 11.5 0.2 1.6 1 1 1 2 2 2 0 AAA domain SIR2 PF02146.17 KKK46286.1 - 2.3e-48 164.4 0.0 3e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KKK46286.1 - 0.00038 20.2 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF3467 PF11950.8 KKK46287.1 - 0.046 13.9 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) Cys_rich_CPXG PF14255.6 KKK46287.1 - 0.05 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG Zn-C2H2_12 PF18112.1 KKK46287.1 - 0.099 13.1 0.7 0.18 12.3 0.7 1.4 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain FlaC_arch PF05377.11 KKK46287.1 - 0.22 12.0 0.6 7.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-C2H2_6 PF13912.6 KKK46287.1 - 0.23 11.5 1.2 0.64 10.1 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Ras PF00071.22 KKK46288.1 - 4.3e-37 127.2 0.0 4.8e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46288.1 - 5.6e-23 81.4 0.0 7.5e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46288.1 - 0.0026 17.2 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK46288.1 - 0.027 13.8 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region LEA_5 PF00477.17 KKK46288.1 - 0.028 14.9 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 Small hydrophilic plant seed protein Proteasome PF00227.26 KKK46289.1 - 2e-53 180.7 0.0 2.4e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK46289.1 - 6.6e-15 54.5 0.3 4.4e-14 51.8 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HATPase_c PF02518.26 KKK46292.1 - 2e-25 89.5 0.1 4.1e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK46292.1 - 1.4e-10 41.1 0.1 2.6e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KKK46292.1 - 2.3e-05 24.6 0.2 6.5e-05 23.1 0.2 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 KKK46292.1 - 0.00053 19.9 0.1 0.0019 18.1 0.1 2.0 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 KKK46292.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 KKK46292.1 - 0.0043 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 KKK46292.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KKK46292.1 - 0.0077 16.5 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KKK46292.1 - 0.027 14.5 0.0 0.078 13.0 0.0 1.9 1 0 0 1 1 1 0 PAS fold Ras PF00071.22 KKK46293.1 - 9.3e-49 165.1 0.5 1.4e-48 164.6 0.5 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46293.1 - 9.3e-29 100.1 0.2 2e-28 99.0 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46293.1 - 1.6e-15 57.0 0.3 3.3e-15 56.0 0.3 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK46293.1 - 1e-05 25.0 0.8 8e-05 22.1 0.7 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KKK46293.1 - 0.0087 15.3 4.5 0.032 13.4 3.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KKK46293.1 - 0.012 15.5 0.3 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KKK46293.1 - 0.02 15.2 0.0 0.069 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 KKK46293.1 - 0.051 13.1 0.1 0.089 12.3 0.1 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain tRNA-synt_1 PF00133.22 KKK46294.1 - 2.2e-57 194.6 3.7 7.8e-41 140.0 0.1 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KKK46294.1 - 5e-23 81.5 8.9 1.9e-10 40.0 0.0 3.9 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KKK46294.1 - 4.6e-09 36.0 6.2 0.00027 20.4 0.0 3.2 4 0 0 4 4 4 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KKK46294.1 - 7.9e-09 35.6 1.3 7.9e-09 35.6 1.3 2.6 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 KKK46294.1 - 7.5e-05 21.8 0.0 0.011 14.7 0.1 2.7 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1_2 PF13603.6 KKK46294.1 - 0.00033 20.2 0.4 0.0023 17.5 0.0 2.3 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1b PF00579.25 KKK46294.1 - 0.024 14.0 0.1 0.058 12.7 0.1 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) PAS PF00989.25 KKK46295.1 - 4.6e-42 142.6 2.8 2.6e-10 40.3 0.0 5.5 5 0 0 5 5 5 5 PAS fold PAS_9 PF13426.7 KKK46295.1 - 5.4e-42 142.3 12.5 2.5e-11 43.7 0.0 5.4 5 0 0 5 5 5 5 PAS domain PAS_3 PF08447.12 KKK46295.1 - 2.8e-41 139.7 0.9 7e-17 61.5 0.0 3.9 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 KKK46295.1 - 4.4e-32 110.6 0.0 2.7e-08 34.0 0.0 5.3 5 0 0 5 5 5 4 PAS fold PAS_8 PF13188.7 KKK46295.1 - 3.6e-31 106.6 0.1 3.7e-07 30.0 0.0 5.5 5 0 0 5 5 5 5 PAS domain HATPase_c PF02518.26 KKK46295.1 - 1.8e-22 80.0 3.6 1.8e-22 80.0 0.4 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK46295.1 - 2.2e-10 40.4 0.3 3e-09 36.8 0.1 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_11 PF14598.6 KKK46295.1 - 1.5e-09 37.9 0.1 0.0011 19.1 0.0 4.4 4 1 0 4 4 4 2 PAS domain PAS_10 PF13596.6 KKK46295.1 - 0.0022 18.6 0.9 7.2 7.3 0.0 4.4 4 0 0 4 4 4 1 PAS domain PAS_7 PF12860.7 KKK46295.1 - 0.0026 17.9 2.6 15 5.8 0.0 5.6 5 2 0 5 5 5 1 PAS fold MEKHLA PF08670.11 KKK46295.1 - 0.0075 16.2 0.1 0.089 12.7 0.0 2.4 2 0 0 2 2 2 1 MEKHLA domain DUF4065 PF13274.6 KKK46295.1 - 0.35 11.8 2.9 7.2 7.5 0.5 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Aminotran_3 PF00202.21 KKK46296.1 - 1.6e-74 251.0 0.0 2.3e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III AmiS_UreI PF02293.15 KKK46297.1 - 0.00016 21.8 8.6 0.00025 21.1 8.1 1.7 1 1 0 1 1 1 1 AmiS/UreI family transporter FixQ PF05545.11 KKK46297.1 - 0.0098 15.8 0.2 0.0098 15.8 0.2 2.8 3 0 0 3 3 3 1 Cbb3-type cytochrome oxidase component FixQ DUF3784 PF12650.7 KKK46297.1 - 0.021 15.0 1.6 0.021 15.0 1.6 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) DUF2207 PF09972.9 KKK46297.1 - 1.6 7.4 17.5 3.5e+03 -3.6 17.5 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_M23 PF01551.22 KKK46298.1 - 1.8e-07 31.3 0.0 2.7e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M23 CSD PF00313.22 KKK46300.1 - 6.5e-28 96.4 1.5 7.6e-28 96.2 1.5 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KKK46300.1 - 0.0068 16.1 0.4 0.015 15.0 0.4 1.8 1 1 0 1 1 1 1 Ribonuclease B OB domain PAS_9 PF13426.7 KKK46301.1 - 2.3e-64 214.1 14.9 9.3e-12 45.1 0.1 7.3 7 0 0 7 7 7 7 PAS domain PAS_4 PF08448.10 KKK46301.1 - 9.9e-47 157.8 0.0 1.3e-11 44.7 0.0 7.3 7 0 0 7 7 7 5 PAS fold PAS PF00989.25 KKK46301.1 - 1.8e-43 147.1 0.0 3.7e-09 36.6 0.0 7.5 7 0 0 7 7 7 6 PAS fold PAS_3 PF08447.12 KKK46301.1 - 3.6e-37 126.5 1.0 1.2e-10 41.5 0.0 7.0 7 0 0 7 7 7 4 PAS fold PAS_8 PF13188.7 KKK46301.1 - 1.5e-35 120.6 0.0 3e-08 33.5 0.0 6.8 6 0 0 6 6 6 5 PAS domain HATPase_c PF02518.26 KKK46301.1 - 1.1e-25 90.3 0.3 3.5e-25 88.7 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_11 PF14598.6 KKK46301.1 - 1.5e-11 44.4 0.0 0.053 13.7 0.0 6.2 6 1 1 7 7 7 3 PAS domain HisKA PF00512.25 KKK46301.1 - 2.3e-10 40.4 0.1 6.3e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 KKK46301.1 - 1.8e-07 31.3 6.9 0.08 13.1 0.1 8.0 8 2 0 8 8 8 2 PAS fold PAS_10 PF13596.6 KKK46301.1 - 0.0036 17.9 1.3 0.28 11.8 0.0 4.0 4 0 0 4 4 3 1 PAS domain SirA PF10747.9 KKK46301.1 - 0.0096 16.3 1.5 0.0096 16.3 1.5 3.0 3 0 0 3 3 2 1 Sporulation inhibitor of replication protein SirA HATPase_c_3 PF13589.6 KKK46301.1 - 0.0099 15.7 0.3 0.043 13.6 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bcr-Abl_Oligo PF09036.10 KKK46301.1 - 0.015 15.3 4.5 0.29 11.2 0.3 3.7 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain HATPase_c_2 PF13581.6 KKK46301.1 - 0.031 14.2 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain TaqI_C PF12950.7 KKK46301.1 - 2.2 8.4 8.4 0.91 9.6 0.9 3.5 3 0 0 3 3 3 0 TaqI-like C-terminal specificity domain VPS11_C PF12451.8 KKK46301.1 - 4.1 7.7 9.5 74 3.7 1.2 4.4 4 0 0 4 4 4 0 Vacuolar protein sorting protein 11 C terminal Nitroreductase PF00881.24 KKK46302.1 - 0.0018 18.3 0.0 0.14 12.2 0.0 3.0 2 2 1 3 3 3 1 Nitroreductase family DUF3874 PF12990.7 KKK46302.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) PepSY_TM PF03929.16 KKK46303.1 - 0.18 11.5 3.0 0.29 10.8 3.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region AMP-binding PF00501.28 KKK46304.1 - 5.4e-46 157.1 0.0 6.3e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KKK46304.1 - 1.1e-10 41.3 0.9 2.6e-10 40.1 0.9 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KKK46304.1 - 0.006 17.5 0.0 0.015 16.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ThiC_Rad_SAM PF01964.18 KKK46305.1 - 9.1e-141 469.4 0.2 1e-140 469.2 0.2 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family zinc_ribbon_2 PF13240.6 KKK46306.1 - 0.0089 15.7 2.0 0.0089 15.7 2.0 1.6 2 0 0 2 2 2 1 zinc-ribbon domain TackOD1 PF18551.1 KKK46306.1 - 0.012 15.3 0.4 0.012 15.3 0.4 1.0 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-ribbon_3 PF13248.6 KKK46306.1 - 0.02 14.3 2.1 1.3 8.5 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-RanBP PF00641.18 KKK46306.1 - 0.029 13.7 1.5 0.051 12.9 1.5 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Stc1 PF12898.7 KKK46306.1 - 0.043 14.4 0.6 0.052 14.1 0.6 1.1 1 0 0 1 1 1 0 Stc1 domain DNTTIP1_dimer PF18192.1 KKK46306.1 - 0.05 14.0 0.1 0.081 13.3 0.1 1.5 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain Lar_restr_allev PF14354.6 KKK46306.1 - 0.14 12.6 1.8 2 8.8 2.2 2.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar YhfH PF14149.6 KKK46306.1 - 1.5 8.9 5.9 1.7 8.7 0.6 2.5 1 1 1 2 2 2 0 YhfH-like protein zinc_ribbon_2 PF13240.6 KKK46308.1 - 0.00014 21.4 0.4 0.00025 20.7 0.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KKK46308.1 - 0.0016 17.7 0.2 0.0024 17.2 0.2 1.2 1 0 0 1 1 1 1 zinc-ribbon domain zf-Di19 PF05605.12 KKK46308.1 - 0.0066 16.7 0.9 0.0099 16.2 0.9 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 KKK46308.1 - 0.0076 16.3 0.0 0.0091 16.0 0.0 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-NADH-PPase PF09297.11 KKK46308.1 - 0.013 15.2 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KKK46308.1 - 0.085 12.8 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Nudix N-terminal C_GCAxxG_C_C PF09719.10 KKK46309.1 - 5.8e-15 55.6 0.0 1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) HTH_24 PF13412.6 KKK46311.1 - 5.6e-08 32.2 0.0 1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 KKK46311.1 - 0.00042 20.1 0.0 0.00054 19.8 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 KKK46311.1 - 0.00072 19.4 0.0 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 MarR family HTH_5 PF01022.20 KKK46311.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Mga PF08280.11 KKK46311.1 - 0.028 14.5 0.0 0.094 12.8 0.0 1.8 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_34 PF13601.6 KKK46311.1 - 0.029 14.6 0.3 0.33 11.1 0.0 2.0 1 1 1 2 2 2 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 KKK46311.1 - 0.046 13.5 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 KKK46311.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 MarR family Sacchrp_dh_NADP PF03435.18 KKK46312.1 - 5.6e-17 62.2 0.0 8.3e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 KKK46312.1 - 5.7e-10 39.7 0.0 4.6e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain NAD_binding_10 PF13460.6 KKK46312.1 - 1.5e-05 25.0 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KKK46312.1 - 0.00023 21.2 0.1 0.00041 20.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KKK46312.1 - 0.0017 17.4 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GARS_N PF02844.15 KKK46312.1 - 0.06 14.1 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Sacchrp_dh_NADP PF03435.18 KKK46313.1 - 1e-17 64.6 0.4 2.2e-17 63.5 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_C PF16653.5 KKK46313.1 - 3.9e-08 33.7 0.1 3e-07 30.8 0.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain NAD_binding_10 PF13460.6 KKK46313.1 - 2.5e-06 27.5 0.2 5.7e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 KKK46313.1 - 4.9e-05 23.4 0.2 0.00013 22.0 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 KKK46313.1 - 0.0026 16.8 0.2 0.0042 16.1 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KKK46313.1 - 0.04 13.3 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KKK46313.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KKK46313.1 - 0.13 11.8 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family PglD_N PF17836.1 KKK46313.1 - 0.17 12.6 0.5 1.7 9.3 0.0 2.6 3 0 0 3 3 3 0 PglD N-terminal domain Amidohydro_3 PF07969.11 KKK46314.1 - 8.4e-31 107.9 0.0 2.6e-15 56.8 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KKK46314.1 - 1.3e-12 47.7 0.8 5.3e-07 29.3 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family TatD_DNase PF01026.21 KKK46314.1 - 0.07 12.5 0.0 0.51 9.7 0.0 2.0 1 1 0 1 1 1 0 TatD related DNase Fe-ADH PF00465.19 KKK46315.1 - 2.3e-84 283.3 0.0 2.6e-84 283.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK46315.1 - 9.2e-19 68.1 0.1 3e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF4532 PF15046.6 KKK46315.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) AFOR_C PF01314.18 KKK46316.1 - 9e-91 304.7 0.0 1.2e-90 304.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK46316.1 - 1.8e-68 230.4 0.1 9.7e-68 227.9 0.0 2.0 2 0 0 2 2 2 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain TBPIP PF07106.13 KKK46318.1 - 0.087 12.8 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Response_reg PF00072.24 KKK46321.1 - 9e-14 51.6 0.9 9.9e-14 51.5 0.9 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Prenyltransf PF01255.19 KKK46322.1 - 1.8e-53 181.3 0.1 2.1e-53 181.2 0.1 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase TSNR_N PF04705.12 KKK46322.1 - 0.049 13.7 0.6 0.32 11.1 0.1 2.1 2 0 0 2 2 2 0 Thiostrepton-resistance methylase, N terminus GCS2 PF04107.13 KKK46324.1 - 0.0087 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) Amidohydro_2 PF04909.14 KKK46325.1 - 4.1e-05 23.5 0.0 0.00011 22.1 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase DUF1499 PF07386.11 KKK46325.1 - 0.19 12.3 0.0 0.44 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) FPP PF05911.11 KKK46326.1 - 5.9e-05 21.5 10.6 6.4e-05 21.4 10.6 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil KASH_CCD PF14662.6 KKK46326.1 - 0.00022 21.1 24.6 0.024 14.5 15.8 2.4 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KKK46326.1 - 0.00028 21.4 25.3 0.019 15.5 15.4 2.9 1 1 2 3 3 3 3 Apg6 coiled-coil region GAS PF13851.6 KKK46326.1 - 0.00093 18.6 10.4 0.00093 18.6 10.4 2.6 2 1 1 3 3 2 1 Growth-arrest specific micro-tubule binding z-alpha PF02295.17 KKK46326.1 - 0.0018 18.3 3.3 0.0018 18.3 3.3 2.4 2 1 1 3 3 1 1 Adenosine deaminase z-alpha domain CENP-F_leu_zip PF10473.9 KKK46326.1 - 0.002 18.2 27.0 0.0062 16.6 1.2 3.4 2 1 2 4 4 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KKK46326.1 - 0.0072 16.6 15.7 0.076 13.2 1.4 2.4 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) EzrA PF06160.12 KKK46326.1 - 0.0073 14.5 23.7 0.015 13.5 23.3 1.6 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DivIC PF04977.15 KKK46326.1 - 0.014 15.2 28.0 1.6 8.6 3.4 5.7 2 1 2 5 5 5 0 Septum formation initiator ADIP PF11559.8 KKK46326.1 - 0.022 14.8 1.4 0.022 14.8 1.4 2.7 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 KKK46326.1 - 0.041 12.5 19.1 0.066 11.8 17.0 1.8 1 1 0 1 1 1 0 Macoilin family DASH_Dam1 PF08653.10 KKK46326.1 - 0.076 12.8 4.9 1 9.2 0.5 3.6 3 1 0 3 3 2 0 DASH complex subunit Dam1 PI3K_P85_iSH2 PF16454.5 KKK46326.1 - 0.077 12.6 28.2 0.9 9.1 8.6 3.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF948 PF06103.11 KKK46326.1 - 0.087 13.1 0.2 0.087 13.1 0.2 3.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) CheZ PF04344.13 KKK46326.1 - 0.099 12.6 9.1 0.37 10.7 3.4 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF3450 PF11932.8 KKK46326.1 - 0.1 11.9 19.3 0.047 13.0 1.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Laminin_I PF06008.14 KKK46326.1 - 0.18 11.5 20.1 0.37 10.4 16.6 2.3 1 1 1 2 2 2 0 Laminin Domain I YabA PF06156.13 KKK46326.1 - 0.18 12.5 22.2 2.7 8.7 2.1 4.1 1 1 1 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 KKK46326.1 - 0.19 12.0 22.3 4.1 7.7 3.2 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 KKK46326.1 - 0.29 11.6 14.3 4.8 7.7 0.0 4.6 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 KKK46326.1 - 0.44 11.0 19.9 0.4 11.1 17.6 1.8 1 1 1 2 2 2 0 Fez1 SKA1 PF07160.12 KKK46326.1 - 0.45 10.3 15.4 0.53 10.1 7.0 2.6 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Nup88 PF10168.9 KKK46326.1 - 0.46 8.2 19.3 1.1 7.0 18.1 1.8 1 1 1 2 2 2 0 Nuclear pore component CENP-Q PF13094.6 KKK46326.1 - 0.47 10.7 19.9 15 5.8 14.4 3.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.12 KKK46326.1 - 0.68 10.0 13.5 1.8 8.6 1.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 KKK46326.1 - 0.97 9.9 19.6 3.8 8.0 3.2 3.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Mt_ATP-synt_D PF05873.12 KKK46326.1 - 0.98 9.3 7.9 0.4 10.5 3.0 2.3 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) BST2 PF16716.5 KKK46326.1 - 0.99 10.0 0.1 0.99 10.0 0.1 4.1 1 1 4 5 5 5 0 Bone marrow stromal antigen 2 Jnk-SapK_ap_N PF09744.9 KKK46326.1 - 1.3 9.2 23.6 1.2 9.3 1.0 3.1 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 KKK46326.1 - 1.6 8.9 28.5 0.35 11.0 3.7 4.7 3 1 0 4 4 4 0 bZIP transcription factor ZapB PF06005.12 KKK46326.1 - 1.7 9.1 28.9 1.5 9.3 6.4 4.0 1 1 2 4 4 4 0 Cell division protein ZapB DUF4349 PF14257.6 KKK46326.1 - 2.1 7.8 9.3 2.8 7.3 4.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4349) Csm1_N PF18504.1 KKK46326.1 - 2.3 8.6 26.2 2 8.8 4.2 4.3 1 1 3 5 5 5 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 KKK46326.1 - 2.4 9.1 22.5 1.4 9.9 12.9 2.9 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain Atg14 PF10186.9 KKK46326.1 - 3.2 6.8 22.7 0.062 12.4 5.0 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_Maf PF03131.17 KKK46326.1 - 3.3 8.3 16.6 1 9.9 1.1 3.5 1 1 3 4 4 4 0 bZIP Maf transcription factor SHE3 PF17078.5 KKK46326.1 - 4.4 6.9 27.7 1.8 8.2 5.4 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 NPV_P10 PF05531.12 KKK46326.1 - 6.5 7.3 10.8 0.15 12.5 1.0 3.1 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 KKK46326.1 - 6.9 7.5 19.2 7.9 7.3 0.4 4.6 2 1 4 6 6 5 0 Occludin homology domain Sec34 PF04136.15 KKK46326.1 - 8.1 6.3 16.1 7.4 6.4 0.6 3.4 2 1 2 4 4 4 0 Sec34-like family Fib_alpha PF08702.10 KKK46326.1 - 8.7 6.5 20.3 2.3 8.4 4.3 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Robl_LC7 PF03259.17 KKK46327.1 - 2.1e-09 37.0 0.0 3.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain MAPKK1_Int PF08923.10 KKK46327.1 - 4e-06 26.6 0.0 5.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Autoind_synth PF00765.17 KKK46327.1 - 0.057 13.0 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Autoinducer synthase LAMTOR5 PF16672.5 KKK46327.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 DAP_epimerase PF01678.19 KKK46330.1 - 3.8e-35 120.7 0.0 2.4e-31 108.4 0.0 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 KKK46330.1 - 7.9e-09 35.4 0.0 3.8e-06 26.6 0.0 2.0 1 1 1 2 2 2 2 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 KKK46330.1 - 2.3e-05 23.6 0.0 3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Proline racemase DUF1896 PF08989.10 KKK46330.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) TrmB PF01978.19 KKK46331.1 - 1.6e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB GLYCAM-1 PF05242.11 KKK46331.1 - 0.004 17.3 1.0 0.0065 16.6 0.2 1.7 2 0 0 2 2 2 1 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) PadR PF03551.14 KKK46331.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family CdhD PF03599.16 KKK46333.1 - 8.7e-36 123.4 0.0 1.1e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Oxidored_molyb PF00174.19 KKK46333.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.5 1 1 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Pterin_bind PF00809.22 KKK46333.1 - 0.17 11.5 0.0 18 4.9 0.0 2.2 1 1 1 2 2 2 0 Pterin binding enzyme CdhD PF03599.16 KKK46334.1 - 7.4e-10 38.1 0.0 1e-07 31.0 0.0 2.4 1 1 1 2 2 2 1 CO dehydrogenase/acetyl-CoA synthase delta subunit Fis1_TPR_C PF14853.6 KKK46335.1 - 0.0081 16.2 0.1 0.0096 16.0 0.1 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat SIR2_2 PF13289.6 KKK46336.1 - 2.3e-13 50.5 0.0 4.7e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 SIR2-like domain Methyltransf_11 PF08241.12 KKK46340.1 - 3.4e-09 37.2 0.0 1.5e-08 35.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK46340.1 - 2.4e-07 31.3 0.0 7e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK46340.1 - 2e-06 27.8 0.0 7.1e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK46340.1 - 0.00038 20.3 0.0 0.0012 18.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain HARP PF07443.13 KKK46340.1 - 0.047 13.3 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 HepA-related protein (HARP) Methyltransf_12 PF08242.12 KKK46340.1 - 0.049 14.4 0.0 0.58 10.9 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 KKK46340.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RcbX PF02341.15 KKK46340.1 - 0.13 12.6 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 RbcX protein RNR_Alpha PF17975.1 KKK46341.1 - 1.6e-35 121.6 0.0 5e-35 120.0 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 KKK46341.1 - 2.8e-09 36.1 0.5 0.067 11.7 0.0 3.3 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 KKK46341.1 - 0.13 12.9 0.2 0.35 11.5 0.2 1.8 1 0 0 1 1 1 0 ATP cone domain tRNA_synthFbeta PF17759.1 KKK46344.1 - 3.7e-49 167.1 0.0 4.9e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 KKK46344.1 - 3.4e-13 49.7 0.0 7.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 KKK46344.1 - 7.6e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) B3_4 PF03483.17 KKK46344.1 - 3.9e-07 29.9 0.0 8.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain PDT PF00800.18 KKK46345.1 - 5.6e-61 205.5 0.0 7.9e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 KKK46345.1 - 2.3e-22 79.1 2.9 5.2e-22 78.0 2.9 1.6 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 KKK46345.1 - 2.6e-05 23.9 0.0 6.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain T-box PF00907.22 KKK46345.1 - 0.013 15.8 0.6 0.026 14.8 0.6 1.5 1 0 0 1 1 1 0 T-box RNase_PH PF01138.21 KKK46346.1 - 0.00045 20.7 0.0 0.00048 20.6 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 AMP-binding PF00501.28 KKK46352.1 - 2.1e-93 313.3 0.0 2.4e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KKK46352.1 - 7.2e-20 71.8 0.0 6.7e-19 68.7 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ta0938 PF11494.8 KKK46355.1 - 3.6e-05 24.0 0.3 4.1e-05 23.8 0.3 1.2 1 0 0 1 1 1 1 Ta0938 UPF0515 PF15135.6 KKK46355.1 - 0.01 15.2 0.6 0.01 15.2 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 zf-FCS PF06467.14 KKK46355.1 - 0.017 15.0 2.9 0.024 14.6 2.9 1.4 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif ATPase-cat_bd PF12156.8 KKK46355.1 - 0.024 15.4 3.5 0.03 15.1 3.5 1.2 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase zf-H2C2_2 PF13465.6 KKK46355.1 - 0.045 14.2 1.2 0.045 14.2 1.2 1.7 2 0 0 2 2 2 0 Zinc-finger double domain CMD PF02627.20 KKK46356.1 - 1.1e-12 47.9 0.0 1.4e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PA26 PF04636.13 KKK46356.1 - 2.3e-05 23.5 0.0 2.6e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DehI PF10778.9 KKK46356.1 - 0.0032 17.6 0.1 0.017 15.2 0.1 1.9 1 1 1 2 2 2 1 Halocarboxylic acid dehydrogenase DehI Prenylcys_lyase PF07156.14 KKK46356.1 - 0.17 11.0 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase Longin PF13774.6 KKK46357.1 - 0.00083 19.3 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Mon1 PF03164.14 KKK46357.1 - 0.0015 17.7 0.4 0.0017 17.5 0.4 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 Arc_trans_TRASH PF08394.10 KKK46357.1 - 0.0063 16.8 3.7 0.019 15.3 3.7 1.8 1 1 0 1 1 1 1 Archaeal TRASH domain Ta0938 PF11494.8 KKK46357.1 - 0.019 15.2 0.6 0.097 13.0 0.2 2.1 2 0 0 2 2 2 0 Ta0938 zf-H2C2_2 PF13465.6 KKK46357.1 - 0.28 11.7 4.8 0.21 12.1 1.4 2.1 2 0 0 2 2 2 0 Zinc-finger double domain COX2_TM PF02790.15 KKK46358.1 - 0.0055 16.8 2.8 0.6 10.3 1.2 2.0 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, transmembrane domain PLDc_N PF13396.6 KKK46358.1 - 0.018 15.0 8.4 0.018 15.0 8.4 3.2 1 1 2 3 3 3 0 Phospholipase_D-nuclease N-terminal DUF1673 PF07895.11 KKK46358.1 - 0.018 14.8 2.3 0.026 14.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3413 PF11893.8 KKK46358.1 - 0.07 12.3 2.8 0.083 12.0 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) DUF2062 PF09835.9 KKK46358.1 - 0.071 13.0 2.9 0.12 12.3 0.8 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF3098 PF11297.8 KKK46358.1 - 0.1 12.2 3.4 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) SUR7 PF06687.12 KKK46358.1 - 0.14 11.8 0.8 0.17 11.5 0.8 1.0 1 0 0 1 1 1 0 SUR7/PalI family Zip PF02535.22 KKK46358.1 - 0.26 10.5 1.7 0.32 10.1 0.5 1.6 1 1 1 2 2 2 0 ZIP Zinc transporter LapA_dom PF06305.11 KKK46358.1 - 0.46 10.3 0.2 0.46 10.3 0.2 2.0 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3021 PF11457.8 KKK46358.1 - 0.63 10.4 11.4 0.43 10.9 5.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) DUF202 PF02656.15 KKK46358.1 - 1.1 9.8 5.4 8.7 6.9 5.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) SCIMP PF15050.6 KKK46358.1 - 1.2 9.6 8.6 0.86 10.1 3.9 2.0 1 1 1 2 2 2 0 SCIMP protein DUF3487 PF11990.8 KKK46358.1 - 1.4 8.8 4.6 15 5.5 4.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) DUF4199 PF13858.6 KKK46358.1 - 1.9 8.9 8.5 12 6.3 3.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) CrgA PF06781.12 KKK46358.1 - 2.7 8.1 5.8 3.6 7.7 5.8 1.2 1 0 0 1 1 1 0 Cell division protein CrgA Phage_holin_2_4 PF16082.5 KKK46358.1 - 3.1 7.6 5.4 1.4 8.7 0.9 2.0 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like OAD_gamma PF04277.13 KKK46358.1 - 7 7.3 6.0 0.58 10.8 0.6 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF1706 PF08020.11 KKK46359.1 - 0.032 14.1 0.2 0.043 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) RNA_POL_M_15KD PF02150.16 KKK46360.1 - 9.3e-09 35.0 6.0 1.2e-08 34.6 6.0 1.2 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit zf-RRPl_C4 PF17026.5 KKK46360.1 - 0.0031 17.6 0.5 0.0034 17.5 0.5 1.1 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type zinc-ribbons_6 PF07191.12 KKK46360.1 - 0.0086 16.0 0.6 0.011 15.7 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbons DZR PF12773.7 KKK46360.1 - 0.021 14.8 0.8 0.026 14.5 0.8 1.2 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 KKK46360.1 - 0.022 15.0 1.7 0.032 14.4 1.7 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 KKK46360.1 - 0.77 9.3 6.4 1.5 8.4 1.8 2.4 1 1 0 2 2 2 0 TFIIB zinc-binding HATPase_c PF02518.26 KKK46363.1 - 2.5e-15 57.0 0.1 4.4e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK46363.1 - 2.3e-05 24.2 5.0 4e-05 23.4 4.0 2.0 1 1 0 1 1 1 1 GHKL domain Ribosomal_S19 PF00203.21 KKK46363.1 - 0.13 12.2 1.4 0.84 9.6 0.2 2.4 1 1 1 2 2 2 0 Ribosomal protein S19 Methyltransf_23 PF13489.6 KKK46365.1 - 2.3e-16 60.1 0.0 3.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK46365.1 - 5.6e-16 59.0 0.0 1.6e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK46365.1 - 3.9e-13 49.9 0.0 8.3e-13 48.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK46365.1 - 5.9e-13 48.9 0.0 7.6e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK46365.1 - 2.5e-11 44.2 0.0 6.8e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK46365.1 - 8.2e-09 35.1 0.0 9.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KKK46365.1 - 0.00014 21.5 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KKK46365.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 KKK46365.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 KKK46365.1 - 0.045 13.3 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KKK46365.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MFS_1 PF07690.16 KKK46366.1 - 7.8e-35 120.4 51.8 1.8e-17 63.3 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KKK46366.1 - 5.3e-08 32.1 35.5 1.6e-07 30.6 7.9 3.1 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 KKK46366.1 - 0.0016 17.3 30.7 0.0079 15.1 16.0 2.2 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 KKK46366.1 - 0.0083 14.5 1.2 0.0083 14.5 1.2 3.4 3 1 1 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KKK46366.1 - 0.058 11.8 19.7 0.6 8.4 13.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DDDD PF10161.9 KKK46366.1 - 5.2 6.9 10.8 19 5.1 1.7 4.2 3 1 1 4 4 4 0 Putative mitochondrial precursor protein PEMT PF04191.13 KKK46368.1 - 4.6e-15 55.9 0.8 6.1e-15 55.5 0.8 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 KKK46368.1 - 2.4e-08 33.8 0.1 3e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 KKK46368.1 - 2.8e-06 27.4 2.4 0.00048 20.1 0.1 2.0 1 1 1 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KKK46368.1 - 0.0019 18.6 0.3 0.0039 17.6 0.3 1.6 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KKK46368.1 - 0.0019 17.0 0.1 0.0025 16.7 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family YtpI PF14007.6 KKK46368.1 - 0.16 12.1 0.3 0.16 12.1 0.3 2.0 2 0 0 2 2 2 0 YtpI-like protein YHS PF04945.13 KKK46370.1 - 0.035 14.2 0.7 0.059 13.5 0.7 1.5 1 1 0 1 1 1 0 YHS domain PHF5 PF03660.14 KKK46370.1 - 0.15 12.2 4.6 0.17 12.1 4.6 1.1 1 0 0 1 1 1 0 PHF5-like protein zf-Mss51 PF13824.6 KKK46370.1 - 0.27 11.4 1.7 0.62 10.2 1.8 1.6 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2180 PF09947.9 KKK46370.1 - 1.5 8.9 9.1 0.23 11.5 2.4 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Zn_ribbon_recom PF13408.6 KKK46371.1 - 1.8 9.2 13.8 7.2 7.2 9.3 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF3297 PF11730.8 KKK46372.1 - 0.027 14.4 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) E1-E2_ATPase PF00122.20 KKK46373.1 - 2.4e-49 167.3 1.0 2.4e-49 167.3 1.0 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KKK46373.1 - 5.9e-46 157.4 5.3 1.5e-45 156.0 5.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KKK46373.1 - 9.4e-12 45.2 1.8 1.3e-10 41.5 0.0 3.6 4 0 0 4 4 4 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KKK46373.1 - 5.3e-07 29.6 3.6 0.00011 22.1 0.5 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KKK46373.1 - 0.018 15.5 0.0 0.072 13.5 0.0 2.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF5337 PF17272.2 KKK46373.1 - 0.41 10.5 2.4 0.44 10.4 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5337) zinc_ribbon_2 PF13240.6 KKK46375.1 - 1.2e-06 28.0 20.4 5.9e-05 22.7 5.4 2.2 1 1 2 3 3 3 3 zinc-ribbon domain DZR PF12773.7 KKK46375.1 - 1.2e-05 25.2 0.8 1.8e-05 24.6 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 KKK46375.1 - 6e-05 23.7 0.6 6.4e-05 23.6 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon family zinc-ribbons_6 PF07191.12 KKK46375.1 - 9.9e-05 22.2 0.8 0.00012 22.0 0.8 1.2 1 0 0 1 1 1 1 zinc-ribbons Nudix_N_2 PF14803.6 KKK46375.1 - 0.00012 21.9 1.4 0.22 11.5 0.1 2.4 2 0 0 2 2 2 2 Nudix N-terminal zf-ribbon_3 PF13248.6 KKK46375.1 - 0.00024 20.4 1.2 0.19 11.2 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KKK46375.1 - 0.00048 20.2 2.4 0.00087 19.4 2.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain HypA PF01155.19 KKK46375.1 - 0.0029 17.6 0.6 0.0031 17.5 0.6 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YhfH PF14149.6 KKK46375.1 - 0.0049 16.8 5.2 1.3 9.0 0.1 2.7 1 1 1 2 2 2 2 YhfH-like protein TF_Zn_Ribbon PF08271.12 KKK46375.1 - 0.0061 16.1 3.8 0.13 11.8 0.2 2.2 1 1 1 2 2 2 1 TFIIB zinc-binding DUF1272 PF06906.11 KKK46375.1 - 0.0081 16.2 0.7 0.012 15.7 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) Cript PF10235.9 KKK46375.1 - 0.0084 16.7 0.5 0.0097 16.5 0.5 1.1 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT Zn_ribbon_SprT PF17283.2 KKK46375.1 - 0.014 15.3 0.1 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C3HC4_3 PF13920.6 KKK46375.1 - 0.014 15.2 0.8 0.023 14.5 0.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.14 KKK46375.1 - 0.019 14.8 0.3 6 6.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS NOB1_Zn_bind PF08772.11 KKK46375.1 - 0.027 14.6 4.5 0.4 10.9 4.4 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-RRN7 PF11781.8 KKK46375.1 - 0.027 14.1 0.3 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_7 PF02591.15 KKK46375.1 - 0.045 14.0 0.9 9.1 6.6 0.0 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain A2L_zn_ribbon PF08792.10 KKK46375.1 - 0.055 13.2 4.1 1.4 8.7 0.8 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.11 KKK46375.1 - 0.065 13.2 2.5 0.1 12.6 2.5 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain PLATZ PF04640.14 KKK46375.1 - 0.068 13.8 0.6 0.083 13.5 0.6 1.2 1 0 0 1 1 1 0 PLATZ transcription factor Ribosomal_L37e PF01907.19 KKK46375.1 - 0.068 13.3 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L37e DUF2321 PF10083.9 KKK46375.1 - 0.082 12.5 1.9 0.16 11.6 1.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf_UBZ PF18439.1 KKK46375.1 - 0.099 12.3 2.9 0.46 10.1 0.3 2.1 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger GFA PF04828.14 KKK46375.1 - 0.099 13.0 2.3 0.98 9.8 0.2 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_2 PF13923.6 KKK46375.1 - 0.14 12.0 2.2 0.21 11.5 2.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_ligase_ZBD PF03119.16 KKK46375.1 - 0.32 11.0 0.3 0.32 11.0 0.3 2.2 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc_ribbon_9 PF14369.6 KKK46375.1 - 0.39 11.0 2.9 0.99 9.7 2.7 1.8 1 1 0 1 1 1 0 zinc-ribbon Rubredoxin_2 PF18073.1 KKK46375.1 - 0.92 9.3 6.8 2.5 7.9 0.8 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-LITAF-like PF10601.9 KKK46375.1 - 1.5 9.1 8.1 14 6.0 0.2 3.1 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain HTH_AsnC-type PF13404.6 KKK46376.1 - 1.6e-12 47.0 0.2 2.6e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK46376.1 - 1.4e-11 43.7 0.1 2.7e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 KKK46376.1 - 0.00046 20.1 0.1 0.0049 16.8 0.0 2.1 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain MarR PF01047.22 KKK46376.1 - 0.002 18.0 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 KKK46376.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 KKK46376.1 - 0.01 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_Tnp_Tc3_2 PF01498.18 KKK46376.1 - 0.066 13.5 0.4 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 Transposase TrmB PF01978.19 KKK46376.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 KKK46377.1 - 1.6e-11 43.9 0.0 2.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK46377.1 - 2.2e-10 39.9 0.1 3.1e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 KKK46377.1 - 0.00028 20.7 0.0 0.0011 18.8 0.0 1.8 1 1 1 2 2 2 1 Bacterial regulatory protein, arsR family MarR PF01047.22 KKK46377.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 MarR family Sigma70_r4_2 PF08281.12 KKK46377.1 - 0.02 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 KKK46377.1 - 0.031 13.8 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 TFA2_Winged_2 PF18121.1 KKK46377.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 TFA2 Winged helix domain 2 HTH_23 PF13384.6 KKK46377.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain SNAP PF14938.6 KKK46379.1 - 3.5e-05 23.4 4.5 3.5e-05 23.4 4.5 5.6 2 1 0 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KKK46379.1 - 0.0031 17.8 26.1 0.0096 16.2 4.4 5.8 7 1 0 7 7 7 2 Tetratricopeptide repeat MIT PF04212.18 KKK46379.1 - 0.0099 15.9 1.8 0.0099 15.9 1.8 7.4 6 2 2 8 8 8 2 MIT (microtubule interacting and transport) domain BORCS7 PF16088.5 KKK46379.1 - 0.021 15.1 0.7 0.021 15.1 0.7 2.5 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 TPR_7 PF13176.6 KKK46379.1 - 0.22 11.6 8.3 18 5.7 0.8 5.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Sec8_exocyst PF04048.14 KKK46379.1 - 0.54 10.1 6.7 0.54 10.1 0.2 3.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Syntaxin_2 PF14523.6 KKK46379.1 - 8.5 6.8 8.6 13 6.2 0.2 4.0 4 1 0 4 4 4 0 Syntaxin-like protein MarR PF01047.22 KKK46380.1 - 0.00072 19.4 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 KKK46380.1 - 0.0013 19.1 0.1 0.0017 18.7 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_11 PF08279.12 KKK46380.1 - 0.0066 16.4 0.4 0.0094 15.9 0.4 1.2 1 0 0 1 1 1 1 HTH domain Phage_rep_O PF04492.13 KKK46380.1 - 0.012 16.2 0.4 0.016 15.8 0.4 1.2 1 0 0 1 1 1 0 Bacteriophage replication protein O MarR_2 PF12802.7 KKK46380.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 MarR family HTH_45 PF14947.6 KKK46380.1 - 0.022 14.8 1.1 0.025 14.5 1.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix Crp PF00325.20 KKK46380.1 - 0.033 13.8 0.5 0.051 13.2 0.5 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Spo7_2_N PF15407.6 KKK46380.1 - 0.042 13.5 0.7 0.085 12.5 0.7 1.6 1 1 0 1 1 1 0 Sporulation protein family 7 HTH_Crp_2 PF13545.6 KKK46380.1 - 0.047 13.7 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 KKK46380.1 - 0.086 12.7 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Thiolase_N PF00108.23 KKK46381.1 - 9.4e-09 35.0 0.0 1.1e-08 34.8 0.0 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain GHMP_kinases_C PF08544.13 KKK46381.1 - 0.099 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Fer4 PF00037.27 KKK46384.1 - 4.4e-12 45.3 12.9 6.4e-07 28.9 3.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK46384.1 - 2.6e-09 37.5 12.0 3.6e-09 37.1 12.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK46384.1 - 1.4e-08 34.6 9.9 5.2e-05 23.4 2.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 KKK46384.1 - 2e-08 34.0 16.3 2.2e-05 24.3 6.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK46384.1 - 1.3e-07 31.7 11.7 2.7e-07 30.7 11.8 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK46384.1 - 1.5e-07 31.4 14.0 0.001 19.2 4.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46384.1 - 1.6e-07 31.3 27.3 9.8e-06 25.6 14.0 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46384.1 - 1.9e-07 31.9 9.0 0.0014 19.5 1.3 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KKK46384.1 - 7.7e-07 28.8 16.7 0.0015 18.5 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 KKK46384.1 - 1.5e-05 25.8 4.7 0.069 14.0 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK46384.1 - 2.9e-05 24.7 7.1 0.031 15.0 0.7 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.7 KKK46384.1 - 3.7e-05 24.4 14.4 0.028 15.4 4.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 KKK46384.1 - 4.6e-05 23.9 7.5 0.055 14.0 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 KKK46384.1 - 0.00076 19.9 11.8 0.084 13.3 0.4 2.3 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46384.1 - 0.003 18.1 14.7 0.078 13.5 14.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK46384.1 - 0.023 14.9 11.1 0.57 10.4 2.8 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KKK46384.1 - 3.3 7.9 6.9 10 6.3 6.9 1.7 1 1 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S POR PF01558.18 KKK46385.1 - 5.7e-16 59.1 0.0 6.8e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase UPF0175 PF03683.13 KKK46386.1 - 2.1e-09 36.9 0.9 3.4e-09 36.3 0.2 1.6 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0175) RHH_1 PF01402.21 KKK46386.1 - 2.6e-06 27.2 0.8 2.6e-06 27.2 0.8 2.1 2 1 0 2 2 2 1 Ribbon-helix-helix protein, copG family RHH_4 PF13467.6 KKK46386.1 - 0.00072 19.4 2.0 0.22 11.4 0.2 2.1 2 0 0 2 2 2 2 Ribbon-helix-helix domain RHH_5 PF07878.11 KKK46386.1 - 0.0015 18.4 0.1 0.0036 17.2 0.1 1.7 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 CopG_antitoxin PF12441.8 KKK46386.1 - 0.0018 18.8 1.1 0.0075 16.8 0.1 2.0 2 0 0 2 2 2 1 CopG antitoxin of type II toxin-antitoxin system Propep_M14 PF02244.16 KKK46386.1 - 0.02 15.3 0.3 2.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Carboxypeptidase activation peptide HicB_lk_antitox PF15919.5 KKK46386.1 - 0.14 12.3 0.1 1.4 9.0 0.0 2.1 2 1 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system DNA_ligase_aden PF01653.18 KKK46387.1 - 6.5e-45 153.6 0.5 1e-44 153.0 0.5 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 KKK46387.1 - 8.2e-19 67.3 0.9 4.7e-18 64.9 0.1 2.6 3 0 0 3 3 3 1 NAD-dependent DNA ligase OB-fold domain BRCT PF00533.26 KKK46387.1 - 8.5e-10 38.9 0.1 3e-09 37.1 0.1 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 KKK46387.1 - 2.6e-09 37.5 0.1 6.7e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KKK46387.1 - 0.00011 22.2 0.1 0.00047 20.2 0.1 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif ATP-grasp_2 PF08442.10 KKK46387.1 - 0.022 14.3 0.1 0.081 12.5 0.1 2.0 1 0 0 1 1 1 0 ATP-grasp domain Methyltransf_15 PF09445.10 KKK46388.1 - 8.9e-16 57.9 0.4 3.5e-15 56.0 0.2 2.2 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Thump_like PF18096.1 KKK46388.1 - 5e-07 29.6 0.0 1.5e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 THUMP domain-like Pex14_N PF04695.13 KKK46388.1 - 9.4e-05 23.1 0.1 0.00017 22.3 0.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_3 PF01596.17 KKK46388.1 - 0.00026 20.2 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.16 KKK46388.1 - 0.0034 17.2 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.17 KKK46388.1 - 0.0082 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KKK46388.1 - 0.015 16.0 0.0 0.039 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KKK46388.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 KKK46388.1 - 0.048 13.5 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Polbeta PF18765.1 KKK46390.1 - 1.1e-11 44.7 1.2 1.3e-11 44.4 1.2 1.2 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KKK46390.1 - 7.8e-05 22.9 0.3 0.00011 22.5 0.3 1.3 1 1 0 1 1 1 1 Nucleotidyltransferase domain DUF86 PF01934.17 KKK46391.1 - 2e-19 69.6 0.2 2.4e-19 69.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF86 HEPN_Cthe2314 PF18730.1 KKK46391.1 - 0.056 13.5 1.1 0.085 12.9 0.2 1.8 2 1 0 2 2 2 0 Cthe_2314-like HEPN HEPN_Swt1 PF18731.1 KKK46391.1 - 0.059 13.7 0.0 0.47 10.8 0.0 2.2 3 0 0 3 3 3 0 Swt1-like HEPN Glyoxalase PF00903.25 KKK46392.1 - 5.4e-05 23.4 0.2 0.00018 21.7 0.2 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF433 PF04255.14 KKK46393.1 - 6.8e-19 67.5 0.1 9.9e-19 67.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF433) CitMHS PF03600.16 KKK46394.1 - 1.1e-20 74.0 46.9 7.4e-13 48.3 21.6 2.5 1 1 1 2 2 2 2 Citrate transporter MazE_antitoxin PF04014.18 KKK46395.1 - 7.1e-07 29.0 0.1 9.2e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PrlF_antitoxin PF15937.5 KKK46395.1 - 1.7e-05 25.2 0.2 2e-05 24.9 0.2 1.1 1 0 0 1 1 1 1 prlF antitoxin for toxin YhaV_toxin MraZ PF02381.18 KKK46395.1 - 8.3e-05 22.5 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 MraZ protein, putative antitoxin-like PIN PF01850.21 KKK46396.1 - 1.2e-09 38.7 0.1 1.7e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 PIN domain LRR_4 PF12799.7 KKK46400.1 - 7e-19 67.6 41.2 1.9e-07 31.3 3.2 6.1 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK46400.1 - 2.3e-10 40.1 33.5 8.8e-06 25.4 8.5 4.7 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 KKK46400.1 - 4.2e-07 29.6 15.7 4.6e-07 29.5 8.0 3.2 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 KKK46400.1 - 4.5 7.6 26.7 2.1 8.6 0.3 6.8 7 0 0 7 7 7 0 Leucine Rich repeat CNOT1_TTP_bind PF16417.5 KKK46401.1 - 0.0054 15.9 0.6 0.0085 15.3 0.6 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain COPI_assoc PF08507.10 KKK46401.1 - 0.0061 16.6 4.3 0.0094 16.0 4.3 1.3 1 0 0 1 1 1 1 COPI associated protein DUF3376 PF11856.8 KKK46401.1 - 0.083 11.9 0.0 0.096 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Wzy_C PF04932.15 KKK46401.1 - 0.21 11.2 4.8 0.33 10.6 4.7 1.4 1 1 0 1 1 1 0 O-Antigen ligase MEDS PF14417.6 KKK46402.1 - 2.7e-45 154.1 0.1 7.7e-45 152.6 0.0 1.8 2 0 0 2 2 2 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HATPase_c PF02518.26 KKK46402.1 - 4e-16 59.5 1.1 1.1e-15 58.0 0.3 2.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK46402.1 - 2e-05 24.5 5.2 3.2e-05 23.9 0.4 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 KKK46402.1 - 0.0017 18.2 4.5 0.0026 17.6 1.2 2.8 1 1 1 2 2 2 1 GHKL domain SSrecog PF03531.14 KKK46402.1 - 0.19 11.6 1.2 28 4.7 0.0 2.8 2 0 0 2 2 2 0 Structure-specific recognition protein (SSRP1) ISG65-75 PF11727.8 KKK46402.1 - 0.73 9.0 10.1 1.7 7.8 10.1 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein AAA_11 PF13086.6 KKK46402.1 - 2.1 8.1 12.5 1.9 8.2 10.9 1.6 1 1 0 1 1 1 0 AAA domain Cupin_3 PF05899.12 KKK46403.1 - 8.3e-22 76.7 0.6 9.6e-22 76.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KKK46403.1 - 0.0013 18.4 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 KKK46403.1 - 0.0083 15.9 0.1 0.0094 15.7 0.1 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Ectoine_synth PF06339.12 KKK46403.1 - 0.021 15.0 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Ectoine synthase Epsilon_antitox PF08998.11 KKK46405.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Ras PF00071.22 KKK46406.1 - 6.4e-44 149.4 0.0 7.3e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46406.1 - 8.2e-30 103.5 0.0 1.1e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46406.1 - 1.4e-12 47.5 0.1 1.6e-12 47.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK46406.1 - 2.9e-06 26.8 0.0 4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK46406.1 - 0.00029 20.3 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KKK46406.1 - 0.00091 19.2 0.1 1.3 8.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KKK46406.1 - 0.0052 17.0 1.3 0.1 12.9 1.2 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KKK46406.1 - 0.013 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 KKK46406.1 - 0.016 14.9 0.1 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 KKK46406.1 - 0.027 14.3 0.9 0.64 9.8 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KKK46406.1 - 0.049 13.4 0.2 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KKK46406.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF3262 PF11660.8 KKK46407.1 - 0.11 12.9 0.5 0.11 12.9 0.5 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3262) DUF2070 PF09843.9 KKK46407.1 - 5.9 5.1 28.6 0.053 11.8 16.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) DUF202 PF02656.15 KKK46407.1 - 7.5 7.1 16.4 12 6.4 0.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Mon1 PF03164.14 KKK46408.1 - 3.4e-06 26.4 0.0 4.3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 PRD PF00874.20 KKK46408.1 - 0.016 15.5 0.6 0.76 10.1 0.0 2.1 1 1 1 2 2 2 0 PRD domain Mating_N PF12731.7 KKK46408.1 - 0.12 12.5 0.7 0.21 11.7 0.2 1.6 2 0 0 2 2 2 0 Mating-type protein beta 1 PIN_9 PF18477.1 KKK46409.1 - 4.3e-18 65.7 0.1 1.8e-17 63.7 0.1 1.8 1 1 0 1 1 1 1 PIN like domain PIN_4 PF13638.6 KKK46409.1 - 1.4e-06 28.7 0.2 1.9e-06 28.2 0.2 1.1 1 0 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KKK46409.1 - 0.00093 19.7 3.7 0.0014 19.2 3.6 1.3 1 1 0 1 1 1 1 PIN domain Fcf1 PF04900.12 KKK46409.1 - 0.03 14.7 0.0 0.049 14.0 0.0 1.4 1 1 0 1 1 1 0 Fcf1 Ras PF00071.22 KKK46410.1 - 1.7e-41 141.5 0.0 1.9e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46410.1 - 2e-26 92.5 0.0 2.6e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46410.1 - 1.5e-13 50.6 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK46410.1 - 0.003 17.0 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK46410.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KKK46410.1 - 0.068 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_S2 PF00318.20 KKK46410.1 - 0.069 12.4 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 NTPase_1 PF03266.15 KKK46410.1 - 0.087 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 KKK46410.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 KKK46410.1 - 0.15 12.1 0.2 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fe-ADH PF00465.19 KKK46411.1 - 6.7e-20 71.2 0.0 7.4e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Glyco_hydro_72 PF03198.14 KKK46411.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Glucanosyltransferase RNase_PH PF01138.21 KKK46414.1 - 1.9e-30 106.1 0.0 2.5e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KKK46414.1 - 6.1e-10 39.0 0.1 1.1e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CPT_N PF16484.5 KKK46414.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus KH_6 PF15985.5 KKK46415.1 - 8.7e-07 29.2 0.1 1.4e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 KKK46415.1 - 1.4e-05 24.8 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_1 PF00013.29 KKK46415.1 - 1.8e-05 24.5 1.4 4.5e-05 23.2 1.4 1.7 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 KKK46415.1 - 0.00026 20.8 0.3 0.00066 19.5 0.3 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KKK46415.1 - 0.00033 20.5 0.1 0.0024 17.7 0.1 2.3 2 0 0 2 2 2 1 KH domain SBDS_C PF09377.10 KKK46416.1 - 4.8e-21 74.9 3.9 7e-21 74.4 3.9 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KKK46416.1 - 3.6e-12 46.2 0.1 6.8e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF5342 PF17277.2 KKK46416.1 - 0.071 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5342) Proteasome PF00227.26 KKK46417.1 - 5.7e-55 185.8 0.0 7.3e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KKK46417.1 - 2.2e-13 49.6 0.1 4.2e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Profilin PF00235.19 KKK46418.1 - 0.00083 19.6 0.0 0.001 19.4 0.0 1.1 1 0 0 1 1 1 1 Profilin Robl_LC7 PF03259.17 KKK46418.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 2 0 0 2 2 2 0 Roadblock/LC7 domain dCache_1 PF02743.18 KKK46418.1 - 0.021 14.6 0.1 0.028 14.2 0.1 1.3 1 1 0 1 1 1 0 Cache domain DUF2110 PF09883.9 KKK46419.1 - 7.3e-30 104.2 0.1 8.4e-30 104.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2110) Pox_D5 PF03288.16 KKK46419.1 - 0.11 13.0 1.7 3.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Poxvirus D5 protein-like DUF1289 PF06945.13 KKK46419.1 - 0.17 11.8 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Putative_PNPOx PF01243.20 KKK46420.1 - 5e-06 26.6 0.0 6.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KKK46420.1 - 0.00013 21.6 0.1 0.00014 21.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Pyridox_ox_2 PF12900.7 KKK46420.1 - 0.016 15.2 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Acyl_transf_3 PF01757.22 KKK46421.1 - 2e-10 40.3 53.3 3.1e-10 39.7 53.3 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF3681 PF12442.8 KKK46421.1 - 0.13 12.7 7.0 0.4 11.2 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Prok-JAB PF14464.6 KKK46422.1 - 8.5e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GT87 PF09594.10 KKK46425.1 - 3.4e-08 33.5 5.3 4.6e-08 33.1 5.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 87 MutS_V PF00488.21 KKK46426.1 - 9.3e-77 257.3 0.5 2.1e-76 256.2 0.5 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KKK46426.1 - 7.3e-38 130.7 4.7 7.3e-38 130.7 4.7 2.5 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KKK46426.1 - 1.9e-34 118.3 0.0 4.9e-34 117.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KKK46426.1 - 5.7e-23 81.7 0.6 3e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KKK46426.1 - 9.3e-22 77.2 13.3 1.2e-21 76.8 1.8 3.0 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 KKK46426.1 - 0.013 15.1 0.4 0.033 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KKK46426.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCU PF04678.13 KKK46426.1 - 0.12 12.5 4.5 0.11 12.5 1.2 2.5 3 0 0 3 3 3 0 Mitochondrial calcium uniporter ABC_tran PF00005.27 KKK46426.1 - 0.75 10.3 0.0 0.75 10.3 0.0 2.9 3 1 0 3 3 3 0 ABC transporter UPF0449 PF15136.6 KKK46426.1 - 1.2 9.6 7.3 0.24 11.9 3.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Hydrolase_4 PF12146.8 KKK46427.1 - 1.6e-47 161.8 0.0 1.8e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KKK46427.1 - 7.7e-08 32.3 1.0 0.0014 18.4 0.3 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK46427.1 - 1e-05 26.3 0.0 1.5e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KKK46427.1 - 1.1e-05 25.1 0.2 0.0028 17.2 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KKK46427.1 - 7.8e-05 22.3 0.0 0.19 11.3 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KKK46427.1 - 0.00031 20.4 0.0 0.00056 19.6 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 KKK46427.1 - 0.032 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Gamma_PGA_hydro PF05908.11 KKK46427.1 - 0.04 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase Esterase PF00756.20 KKK46427.1 - 0.061 13.0 0.0 0.082 12.5 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 KKK46427.1 - 0.087 12.7 0.0 0.33 10.8 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold PAS_9 PF13426.7 KKK46428.1 - 3e-58 194.5 13.4 2.2e-14 53.6 0.1 5.6 5 0 0 5 5 5 5 PAS domain PAS PF00989.25 KKK46428.1 - 3.8e-48 162.2 0.0 1.1e-10 41.5 0.0 5.4 5 0 0 5 5 5 5 PAS fold PAS_8 PF13188.7 KKK46428.1 - 8.4e-35 118.2 0.0 1.3e-09 37.8 0.0 5.2 6 0 0 6 6 6 4 PAS domain PAS_4 PF08448.10 KKK46428.1 - 1.1e-34 119.0 0.0 5.8e-09 36.2 0.0 5.5 5 0 0 5 5 5 5 PAS fold PAS_3 PF08447.12 KKK46428.1 - 8.2e-24 83.7 0.0 2.7e-05 24.4 0.0 5.7 5 1 0 5 5 5 4 PAS fold HATPase_c PF02518.26 KKK46428.1 - 1.9e-22 79.9 0.6 2.2e-21 76.5 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KKK46428.1 - 1.1e-10 41.4 0.0 3.5e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 KKK46428.1 - 1.6e-08 34.7 1.7 0.0014 18.8 0.0 5.2 6 0 0 6 6 6 1 PAS fold PAS_11 PF14598.6 KKK46428.1 - 2.5e-06 27.6 0.1 0.3 11.2 0.1 4.2 4 0 0 4 4 4 2 PAS domain MEKHLA PF08670.11 KKK46428.1 - 0.0033 17.3 0.2 3.3 7.6 0.0 3.4 3 0 0 3 3 3 1 MEKHLA domain PAS_2 PF08446.11 KKK46428.1 - 0.069 13.8 0.0 8.9 7.0 0.0 3.7 4 0 0 4 4 4 0 PAS fold HATPase_c_3 PF13589.6 KKK46428.1 - 0.11 12.4 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RIO1 PF01163.22 KKK46429.1 - 4.1e-51 173.2 0.9 6.2e-51 172.7 0.9 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KKK46429.1 - 8.7e-20 70.7 0.9 1.6e-19 69.9 0.9 1.5 1 0 0 1 1 1 1 Rio2, N-terminal Pkinase PF00069.25 KKK46429.1 - 2.2e-07 30.6 1.4 5.8e-07 29.1 1.4 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KKK46429.1 - 0.00037 19.9 0.5 0.24 10.7 0.0 2.5 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KKK46429.1 - 0.00041 20.4 0.0 0.028 14.3 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KKK46429.1 - 0.0015 17.4 0.1 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Methyltransf_25 PF13649.6 KKK46430.1 - 1e-13 51.8 0.0 2.4e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK46430.1 - 1.7e-12 47.4 0.2 2.9e-12 46.6 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK46430.1 - 1.9e-12 47.6 0.0 3.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KKK46430.1 - 3.7e-09 36.3 0.1 4.7e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KKK46430.1 - 1.1e-07 31.4 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KKK46430.1 - 1.4e-07 32.1 0.2 3.3e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KKK46430.1 - 3.7e-05 23.6 0.0 4.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK46430.1 - 0.00022 20.8 0.0 0.00048 19.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KKK46430.1 - 0.00028 19.9 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KKK46430.1 - 0.00057 19.9 0.1 0.0012 18.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 KKK46430.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TRM13 PF05206.14 KKK46430.1 - 0.0043 16.6 0.1 0.0068 16.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_18 PF12847.7 KKK46430.1 - 0.0076 16.2 0.0 0.03 14.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KKK46430.1 - 0.052 13.6 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase LSM PF01423.22 KKK46431.1 - 2.1e-20 72.2 0.1 2.4e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KKK46431.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Metallophos PF00149.28 KKK46432.1 - 3.9e-30 105.9 0.5 5.7e-30 105.4 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KKK46432.1 - 2.9e-06 27.6 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KKK46432.1 - 0.00073 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Eco57I PF07669.11 KKK46433.1 - 2.3e-13 50.5 0.3 2.3e-13 50.5 0.3 2.8 3 0 0 3 3 3 1 Eco57I restriction-modification methylase N6_Mtase PF02384.16 KKK46433.1 - 2.4e-13 50.1 0.4 9.6e-12 44.8 0.3 2.7 1 1 0 1 1 1 1 N-6 DNA Methylase TaqI_C PF12950.7 KKK46433.1 - 1.3e-10 41.4 1.2 1.3e-10 41.4 1.2 3.8 4 0 0 4 4 4 1 TaqI-like C-terminal specificity domain MTS PF05175.14 KKK46433.1 - 0.011 15.3 0.0 0.35 10.4 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase small domain UPF0020 PF01170.18 KKK46433.1 - 0.023 14.4 0.0 0.16 11.7 0.0 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 KKK46433.1 - 0.08 12.7 1.7 0.24 11.2 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Hydrolase_4 PF12146.8 KKK46435.1 - 2.2e-17 63.1 0.0 1.6e-14 53.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KKK46435.1 - 1.2e-10 41.5 0.0 3.9e-10 39.8 0.0 1.5 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KKK46435.1 - 2.6e-08 34.1 0.0 3.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KKK46435.1 - 3.2e-07 30.2 0.2 0.00012 21.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KKK46435.1 - 1.1e-05 25.1 0.3 0.00016 21.2 0.3 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KKK46435.1 - 0.00014 22.5 0.0 0.00022 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Imm43 PF15570.6 KKK46435.1 - 0.011 15.7 0.2 0.011 15.7 0.2 2.1 2 0 0 2 2 2 0 Immunity protein 43 DLH PF01738.18 KKK46435.1 - 0.044 13.3 0.0 0.68 9.4 0.0 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family ATPgrasp_YheCD PF14398.6 KKK46436.1 - 4e-05 23.0 0.1 9.8e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 KKK46436.1 - 0.0016 17.8 1.2 0.0052 16.1 0.1 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF3549 PF12069.8 KKK46436.1 - 0.0064 15.6 0.0 0.017 14.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3549) Glyoxalase_5 PF14696.6 KKK46436.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal CLP1_P PF16575.5 KKK46437.1 - 1.1e-26 93.7 0.0 1.6e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 KKK46437.1 - 0.038 13.6 0.2 9 5.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 KKK46437.1 - 0.05 14.0 1.6 0.12 12.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain FmdE PF02663.14 KKK46438.1 - 6.4e-32 110.4 0.0 8.6e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon zf-dskA_traR PF01258.17 KKK46438.1 - 0.00054 19.8 0.1 0.00096 19.0 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger Mut7-C PF01927.16 KKK46439.1 - 2.7e-32 111.9 0.0 3e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF5615 PF18480.1 KKK46439.1 - 3.5e-06 26.7 0.0 9.6e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5615) zf_CopZ PF18423.1 KKK46439.1 - 0.043 13.8 1.1 0.097 12.6 1.1 1.6 1 0 0 1 1 1 0 Zinc binding domain DUF678 PF05077.12 KKK46439.1 - 0.097 12.8 1.2 0.16 12.1 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF678) Zn-ribbon_8 PF09723.10 KKK46441.1 - 0.027 14.6 0.1 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf_C2H2_13 PF18508.1 KKK46441.1 - 0.38 10.4 2.1 0.3 10.7 0.5 1.7 1 1 0 1 1 1 0 Zinc finger domain zf-NADH-PPase PF09297.11 KKK46441.1 - 0.46 10.2 0.3 0.46 10.2 0.3 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Chorismate_synt PF01264.21 KKK46442.1 - 1.2e-122 408.7 0.0 1.4e-122 408.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Phg_2220_C PF09524.10 KKK46442.1 - 0.0093 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Conserved phage C-terminus (Phg_2220_C) PRP4 PF08799.11 KKK46442.1 - 0.2 11.3 0.4 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like EPSP_synthase PF00275.20 KKK46443.1 - 1.1e-105 353.7 0.0 1.4e-105 353.4 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Lig_C PF18330.1 KKK46443.1 - 0.092 12.8 0.1 0.79 9.7 0.0 2.5 3 0 0 3 3 3 0 Ligase Pab1020 C-terminal region Ribosomal_S9 PF00380.19 KKK46444.1 - 1.9e-30 105.9 0.7 2.1e-30 105.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.18 KKK46445.1 - 6.1e-14 52.4 0.1 8.3e-12 45.5 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 PLDc_3 PF13918.6 KKK46445.1 - 0.041 13.5 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 PLD-like domain Ribosomal_L18 PF17135.4 KKK46446.1 - 4.3e-08 32.8 0.0 5.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KKK46446.1 - 0.0001 23.0 0.2 0.00014 22.6 0.2 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_A_bac PF01000.26 KKK46447.1 - 2.7e-25 88.9 0.2 1.8e-24 86.3 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KKK46447.1 - 1.8e-12 46.5 0.0 2.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 KKK46447.1 - 0.00037 20.6 10.3 0.00037 20.6 10.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46447.1 - 0.00081 19.1 0.8 0.00081 19.1 0.8 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_8 PF13183.6 KKK46447.1 - 0.0014 19.0 14.4 0.15 12.5 13.6 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK46447.1 - 0.0018 18.3 20.7 0.011 15.7 2.6 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 KKK46447.1 - 0.0093 16.5 22.9 0.031 14.9 3.0 2.7 1 1 3 4 4 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46447.1 - 0.031 15.2 1.1 0.031 15.2 1.1 3.2 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 KKK46447.1 - 0.046 14.2 2.0 0.046 14.2 2.0 2.9 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK46447.1 - 0.058 13.9 6.7 0.058 13.9 6.7 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK46447.1 - 0.099 12.8 1.2 0.099 12.8 1.2 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_10 PF13237.6 KKK46447.1 - 0.89 9.7 20.5 0.051 13.7 3.1 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK46447.1 - 1.2 9.4 16.4 0.043 14.0 7.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain SHMT PF00464.19 KKK46448.1 - 1.6e-68 231.1 0.0 1.9e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase SelA PF03841.13 KKK46448.1 - 3.4e-05 23.0 0.0 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Aminotran_5 PF00266.19 KKK46448.1 - 4.8e-05 22.5 0.0 0.00036 19.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KKK46448.1 - 7.6e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KKK46448.1 - 0.015 14.6 0.0 0.036 13.4 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase TssO PF17561.2 KKK46448.1 - 0.031 14.4 1.2 0.063 13.4 1.2 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO DUF3452 PF11934.8 KKK46449.1 - 0.39 10.3 15.5 0.081 12.5 5.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) GCD14 PF08704.10 KKK46450.1 - 1e-42 146.5 0.0 1.4e-40 139.5 0.0 2.0 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KKK46450.1 - 2.2e-13 50.3 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 KKK46450.1 - 7.3e-10 38.5 0.1 1.5e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 KKK46450.1 - 1.1e-06 28.6 0.0 5.1e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KKK46450.1 - 1.9e-05 24.6 0.0 3.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK46450.1 - 2.2e-05 25.0 0.0 3.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KKK46450.1 - 5.1e-05 22.9 0.0 9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 KKK46450.1 - 5.5e-05 22.9 0.1 0.00014 21.6 0.1 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 KKK46450.1 - 0.00025 21.7 0.0 0.00043 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KKK46450.1 - 0.00026 20.5 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KKK46450.1 - 0.0029 18.3 0.0 0.0056 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KKK46450.1 - 0.0059 17.6 0.0 0.011 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KKK46450.1 - 0.0064 16.0 0.0 0.015 14.8 0.0 1.6 1 1 1 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KKK46450.1 - 0.0086 16.2 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KKK46450.1 - 0.044 13.8 0.0 0.093 12.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KKK46450.1 - 0.044 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 KKK46450.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF3294 PF07957.11 KKK46451.1 - 0.099 12.4 0.2 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) Roc PF08477.13 KKK46452.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase C6_DPF PF10170.9 KKK46452.1 - 0.41 11.0 6.5 0.36 11.2 0.2 2.9 3 0 0 3 3 3 0 Cysteine-rich domain UPF0047 PF01894.17 KKK46453.1 - 2.2e-30 105.2 0.1 2.5e-30 105.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Arf PF00025.21 KKK46455.1 - 4.6e-25 88.1 0.7 7.8e-25 87.3 0.3 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK46455.1 - 7.6e-22 77.8 3.3 1.1e-21 77.3 3.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KKK46455.1 - 8.2e-10 38.4 0.1 1.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KKK46455.1 - 1.2e-08 35.2 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KKK46455.1 - 9.2e-08 32.2 0.0 4.3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KKK46455.1 - 1.1e-07 31.6 0.2 1.9e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Ras family Thymidylate_kin PF02223.17 KKK46455.1 - 0.018 14.7 0.1 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 KKK46455.1 - 0.025 13.9 0.0 0.081 12.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 KKK46455.1 - 0.062 13.9 0.1 0.16 12.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KKK46455.1 - 0.082 13.1 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KKK46455.1 - 0.1 13.1 0.0 0.38 11.3 0.0 1.8 1 1 0 2 2 2 0 ABC transporter tRNA-synt_1b PF00579.25 KKK46457.1 - 0.0043 16.4 0.6 0.0043 16.4 0.6 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1b PF00579.25 KKK46458.1 - 5.8e-24 84.9 0.0 1.4e-23 83.6 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4261 PF14080.6 KKK46459.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4261) PRA-CH PF01502.18 KKK46460.1 - 8.2e-35 118.5 0.3 1.1e-34 118.1 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase Cas_Cas1 PF01867.16 KKK46460.1 - 0.042 13.0 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 CRISPR associated protein Cas1 HTH_24 PF13412.6 KKK46461.1 - 6.2e-16 57.7 3.8 9.1e-16 57.2 1.7 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 KKK46461.1 - 1.4e-13 50.4 0.1 2.2e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 KKK46461.1 - 2.7e-09 36.8 0.0 4.5e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_11 PF08279.12 KKK46461.1 - 2.4e-06 27.4 0.5 5.3e-06 26.3 0.5 1.7 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 KKK46461.1 - 0.00018 21.5 0.0 0.00079 19.4 0.0 2.0 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KKK46461.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 pXO2-72 PF17443.2 KKK46461.1 - 0.0017 18.6 0.1 0.54 10.5 0.0 3.0 2 1 1 3 3 3 1 Uncharacterized protein pXO2-72 HTH_23 PF13384.6 KKK46461.1 - 0.0017 18.1 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Trp_repressor PF01371.19 KKK46461.1 - 0.0045 17.1 0.2 0.015 15.4 0.1 2.0 2 0 0 2 2 2 1 Trp repressor protein HTH_27 PF13463.6 KKK46461.1 - 0.0072 16.8 0.1 7 7.2 0.1 2.6 2 1 0 2 2 2 1 Winged helix DNA-binding domain DUF5355 PF17306.2 KKK46461.1 - 0.008 15.3 1.0 0.0099 15.0 1.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5355) HTH_34 PF13601.6 KKK46461.1 - 0.014 15.6 0.2 0.047 13.9 0.1 2.0 2 1 0 2 2 2 0 Winged helix DNA-binding domain TFIIE_alpha PF02002.17 KKK46461.1 - 0.025 14.4 1.1 0.095 12.6 0.2 2.1 1 1 1 2 2 2 0 TFIIE alpha subunit HTH_Mga PF08280.11 KKK46461.1 - 0.027 14.5 0.1 0.066 13.3 0.1 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain B-block_TFIIIC PF04182.12 KKK46461.1 - 0.028 14.6 0.4 4 7.7 0.0 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KKK46461.1 - 0.031 14.2 0.0 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.10 KKK46461.1 - 0.035 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_50 PF18024.1 KKK46461.1 - 0.037 13.6 0.1 0.091 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 KKK46461.1 - 0.055 13.0 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Mga PF05043.13 KKK46461.1 - 0.06 13.9 1.0 0.19 12.3 0.2 2.0 2 0 0 2 2 2 0 Mga helix-turn-helix domain MarR PF01047.22 KKK46461.1 - 0.075 13.0 0.8 0.65 10.0 0.1 2.4 3 0 0 3 3 3 0 MarR family HrcA_DNA-bdg PF03444.15 KKK46461.1 - 0.082 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_41 PF14502.6 KKK46461.1 - 0.098 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Cpn60_TCP1 PF00118.24 KKK46462.1 - 1e-141 473.0 15.7 1.1e-141 472.8 15.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PEPCK_GTP PF00821.18 KKK46463.1 - 2.2e-100 336.0 0.0 3e-100 335.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 KKK46463.1 - 3.3e-55 187.1 0.0 4.6e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain PEPCK_ATP PF01293.20 KKK46463.1 - 8.8e-09 34.5 0.0 1.6e-08 33.6 0.0 1.4 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxykinase Ras PF00071.22 KKK46464.1 - 1.7e-07 31.0 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KKK46464.1 - 3.1e-05 23.5 0.0 5.7e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family COG2 PF06148.11 KKK46464.1 - 0.023 14.8 0.3 0.034 14.2 0.3 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SRPRB PF09439.10 KKK46464.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Spore_GerAC PF05504.11 KKK46464.1 - 0.049 13.8 0.1 0.061 13.6 0.1 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Roc PF08477.13 KKK46464.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase STAT_alpha PF01017.20 KKK46464.1 - 0.098 12.5 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain NOG1 PF06858.14 KKK46464.1 - 0.17 11.7 0.6 0.82 9.5 0.6 2.1 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) FlpD PF02662.16 KKK46465.1 - 5.2e-51 171.8 0.0 1.5e-50 170.3 0.0 1.9 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit Pyr_redox_2 PF07992.14 KKK46465.1 - 3e-35 121.9 0.0 2.8e-16 59.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KKK46465.1 - 2.4e-16 59.7 0.2 4.8e-07 29.9 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KKK46465.1 - 6.2e-14 52.2 1.2 2.2e-06 27.3 0.1 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KKK46465.1 - 2.3e-13 50.0 4.0 1.9e-06 27.3 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain Fer4 PF00037.27 KKK46465.1 - 3.9e-13 48.6 44.4 1.3e-05 24.8 2.9 5.8 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_7 PF12838.7 KKK46465.1 - 4.9e-13 49.4 29.0 2.3e-05 24.9 8.3 4.8 4 0 0 4 4 4 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46465.1 - 7.5e-12 45.2 30.6 2.8e-07 30.6 7.4 4.8 4 0 0 4 4 4 2 4Fe-4S dicluster domain DAO PF01266.24 KKK46465.1 - 1.1e-11 45.0 5.2 9.4e-06 25.4 0.2 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Fer4_6 PF12837.7 KKK46465.1 - 7.6e-11 41.6 43.2 3.3e-05 23.7 2.1 5.5 5 0 0 5 5 4 4 4Fe-4S binding domain Pyr_redox_3 PF13738.6 KKK46465.1 - 8.4e-11 41.7 0.6 0.0003 20.1 0.7 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KKK46465.1 - 9.7e-11 42.1 8.5 0.00044 20.7 0.2 4.0 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KKK46465.1 - 6.3e-09 35.4 0.2 0.0015 17.8 0.1 2.7 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KKK46465.1 - 5.2e-08 32.4 11.5 0.00093 18.4 0.4 4.4 4 1 1 5 5 5 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KKK46465.1 - 6.7e-08 32.3 0.3 0.0098 15.2 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KKK46465.1 - 2.4e-07 30.3 3.4 0.008 15.5 0.4 2.4 2 0 0 2 2 2 2 FAD binding domain Fer4_21 PF14697.6 KKK46465.1 - 3.9e-07 30.1 14.8 5.8e-06 26.4 8.7 4.8 4 0 0 4 4 3 2 4Fe-4S dicluster domain HI0933_like PF03486.14 KKK46465.1 - 4.5e-07 28.9 8.9 0.0013 17.6 0.6 2.9 3 1 0 3 3 3 2 HI0933-like protein Fer4_16 PF13484.6 KKK46465.1 - 1.1e-06 29.5 38.1 0.00069 20.5 8.5 4.8 4 0 0 4 4 3 3 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK46465.1 - 1.3e-06 28.4 41.6 0.00022 21.3 0.7 5.7 5 1 1 6 6 5 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46465.1 - 1.2e-05 25.7 32.6 0.0057 17.2 3.8 5.6 4 1 1 5 5 5 4 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK46465.1 - 1.6e-05 25.2 25.9 0.0072 16.7 7.1 4.7 4 0 0 4 4 4 3 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 KKK46465.1 - 0.0001 21.7 0.0 0.62 9.3 0.0 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KKK46465.1 - 0.001 18.2 0.1 1.3 8.0 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KKK46465.1 - 0.0011 19.0 1.4 1.2 9.2 0.1 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KKK46465.1 - 0.0013 18.7 0.2 0.44 10.4 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KKK46465.1 - 0.0021 17.6 0.3 7.7 6.0 0.1 3.6 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KKK46465.1 - 0.0096 16.4 0.1 9.6 6.7 0.0 3.2 3 0 0 3 3 2 0 Putative NAD(P)-binding Fer4_2 PF12797.7 KKK46465.1 - 0.015 15.4 1.6 0.015 15.4 1.6 6.1 6 0 0 6 6 4 0 4Fe-4S binding domain Fer4_15 PF13459.6 KKK46465.1 - 0.029 15.1 0.3 0.029 15.1 0.3 3.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain TrkA_N PF02254.18 KKK46465.1 - 0.041 14.1 0.7 8 6.8 0.0 3.0 2 0 0 2 2 2 0 TrkA-N domain HTH_19 PF12844.7 KKK46465.1 - 0.19 11.8 0.8 34 4.5 0.0 3.6 4 0 0 4 4 3 0 Helix-turn-helix domain Trp_halogenase PF04820.14 KKK46465.1 - 0.3 9.9 2.7 5.4 5.8 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 KKK46465.1 - 0.35 9.9 1.7 7 5.7 0.0 3.6 4 0 0 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_22 PF17179.4 KKK46465.1 - 0.74 10.7 23.1 0.072 13.9 0.7 4.5 4 0 0 4 4 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK46465.1 - 5.2 7.8 42.3 0.054 14.0 3.1 5.1 5 0 0 5 5 4 0 4Fe-4S binding domain Fer4_17 PF13534.6 KKK46466.1 - 1.1e-09 38.6 9.0 1.7e-09 38.1 9.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK46466.1 - 5.2e-09 36.4 9.5 9.4e-09 35.6 9.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46466.1 - 8.8e-06 25.8 10.5 1.8e-05 24.8 10.6 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46466.1 - 0.00017 22.1 10.7 0.0003 21.3 10.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46466.1 - 0.0052 16.9 13.8 0.055 13.6 2.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46466.1 - 0.038 13.8 12.7 0.23 11.3 1.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 KKK46466.1 - 0.23 11.6 14.0 0.34 11.1 2.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 KKK46466.1 - 0.25 11.9 11.1 0.26 11.9 2.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Med23 PF11573.8 KKK46466.1 - 0.34 8.5 0.1 0.37 8.4 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 Fer4_21 PF14697.6 KKK46466.1 - 1.2 9.3 13.9 0.88 9.8 3.1 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK46466.1 - 2 8.6 9.7 3.9 7.7 0.8 2.2 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46466.1 - 2.4 9.2 15.3 84 4.2 15.5 2.3 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain CCG PF02754.16 KKK46467.1 - 1.2e-23 83.2 2.2 2e-13 50.4 1.3 2.3 2 0 0 2 2 2 2 Cysteine-rich domain MTHFR_C PF12225.8 KKK46468.1 - 6.1e-29 99.5 1.3 1.6e-28 98.2 1.3 1.7 1 0 0 1 1 1 1 Methylene-tetrahydrofolate reductase C terminal MTHFR PF02219.17 KKK46469.1 - 3.2e-25 89.0 0.0 4.7e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase HTH_AsnC-type PF13404.6 KKK46470.1 - 2e-14 53.1 0.3 3e-14 52.6 0.3 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 KKK46470.1 - 3.4e-11 42.5 0.9 9.4e-11 41.1 0.9 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 KKK46470.1 - 8.5e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_20 PF12840.7 KKK46470.1 - 2.9e-05 24.0 0.0 0.00021 21.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Mga PF08280.11 KKK46470.1 - 0.00013 21.9 0.4 0.00027 20.9 0.1 1.6 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.12 KKK46470.1 - 0.00015 21.7 0.3 0.0004 20.3 0.2 1.8 2 0 0 2 2 2 1 HTH domain ACT_4 PF13291.6 KKK46470.1 - 0.00084 19.9 0.1 0.014 16.0 0.0 2.2 2 0 0 2 2 2 1 ACT domain Sigma70_r4 PF04545.16 KKK46470.1 - 0.00087 18.8 0.1 0.002 17.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 TrmB PF01978.19 KKK46470.1 - 0.0045 16.8 0.2 0.014 15.2 0.2 1.8 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB ALAD PF00490.21 KKK46470.1 - 0.0067 15.6 0.0 0.0078 15.4 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Sigma70_r4_2 PF08281.12 KKK46470.1 - 0.011 15.4 0.1 0.025 14.2 0.1 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_5 PF01022.20 KKK46470.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_WhiA PF02650.14 KKK46470.1 - 0.027 14.8 0.4 0.053 13.9 0.4 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Mga PF05043.13 KKK46470.1 - 0.027 15.0 0.1 0.056 14.0 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_28 PF13518.6 KKK46470.1 - 0.033 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_12 PF08461.10 KKK46470.1 - 0.042 13.8 0.5 0.085 12.8 0.5 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_DeoR PF08220.12 KKK46470.1 - 0.046 13.5 0.2 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 KKK46470.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain TFIIE_alpha PF02002.17 KKK46470.1 - 0.067 13.1 0.9 0.097 12.5 0.9 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_9 PF08221.11 KKK46470.1 - 0.17 12.0 1.2 0.3 11.2 0.0 1.9 3 0 0 3 3 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Acetyltransf_1 PF00583.25 KKK46471.1 - 2.5e-09 37.4 0.2 3.8e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KKK46471.1 - 1.1e-06 28.7 0.1 6.3e-06 26.2 0.1 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 KKK46471.1 - 1.4e-06 28.1 0.2 3.3e-06 26.9 0.2 1.8 1 1 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 KKK46471.1 - 1.8e-06 27.8 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KKK46471.1 - 2.5e-06 27.8 0.1 5.1e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KKK46471.1 - 0.0034 17.4 0.0 0.015 15.4 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KKK46471.1 - 0.0051 17.5 0.0 0.0073 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KKK46471.1 - 0.019 14.4 0.1 0.036 13.5 0.1 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase Phage_holin_3_6 PF07332.11 KKK46472.1 - 0.19 11.8 2.4 0.23 11.5 2.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III B12-binding PF02310.19 KKK46473.1 - 5.7e-15 55.4 0.0 1.6e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 B12 binding domain Radical_SAM PF04055.21 KKK46473.1 - 1.3e-08 35.4 0.0 2.8e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily PS_pyruv_trans PF04230.13 KKK46473.1 - 0.003 17.5 1.0 0.0067 16.4 0.0 1.9 3 0 0 3 3 3 1 Polysaccharide pyruvyl transferase Fer4_12 PF13353.6 KKK46473.1 - 0.029 14.6 0.1 0.16 12.3 0.1 2.2 1 1 0 1 1 1 0 4Fe-4S single cluster domain Cellulase PF00150.18 KKK46473.1 - 0.065 12.7 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 KKK46473.1 - 0.11 11.9 0.0 0.3 10.5 0.0 1.7 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel LRR_4 PF12799.7 KKK46477.1 - 4.1e-33 112.9 55.5 4.1e-09 36.6 2.0 6.3 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KKK46477.1 - 5.2e-13 48.5 44.4 9.7e-07 28.5 3.0 5.3 3 2 2 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 KKK46477.1 - 2.6e-09 36.8 19.8 8.8e-07 28.6 6.5 3.5 2 1 2 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 KKK46477.1 - 0.044 13.8 4.5 1.3 8.9 0.2 2.6 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 KKK46477.1 - 0.11 12.6 31.8 0.5 10.6 0.5 7.3 8 0 0 8 8 8 0 Leucine Rich repeat LRR_3 PF07725.12 KKK46477.1 - 0.47 10.4 11.1 21 5.2 0.2 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat UB2H PF14814.6 KKK46477.1 - 0.49 10.4 2.8 15 5.7 0.1 4.0 3 2 4 7 7 7 0 Bifunctional transglycosylase second domain LRR_1 PF00560.33 KKK46477.1 - 1.3 9.9 30.5 14 6.7 0.1 7.8 7 2 0 7 7 7 0 Leucine Rich Repeat Pkip-1 PF06878.11 KKK46477.1 - 3.8 7.6 9.3 4.9 7.2 0.4 3.6 1 1 1 4 4 4 0 Pkip-1 protein MTHFR_C PF12225.8 KKK46479.1 - 8.5e-34 115.1 0.6 8.5e-34 115.1 0.6 1.9 2 0 0 2 2 2 1 Methylene-tetrahydrofolate reductase C terminal OKR_DC_1_N PF03709.15 KKK46479.1 - 0.12 12.7 0.1 0.75 10.1 0.1 2.0 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Fer4 PF00037.27 KKK46479.1 - 0.14 12.0 9.4 2 8.4 2.0 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_7 PF12838.7 KKK46479.1 - 0.16 12.6 9.4 12 6.5 9.2 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46479.1 - 0.58 10.4 8.7 3.8 7.8 0.2 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK46479.1 - 0.82 9.8 6.5 4.3 7.5 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain MTHFR PF02219.17 KKK46480.1 - 3.4e-31 108.7 0.0 3.8e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase NiFeSe_Hases PF00374.19 KKK46480.1 - 0.029 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase CCG PF02754.16 KKK46481.1 - 1.4e-17 63.6 3.9 2.7e-14 53.1 0.5 3.0 2 1 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 KKK46481.1 - 2.9e-05 24.4 8.8 2.9e-05 24.4 8.8 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46481.1 - 6.1e-05 23.1 8.8 6.1e-05 23.1 8.8 2.7 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46481.1 - 0.00029 21.3 10.2 0.00029 21.3 10.2 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46481.1 - 0.00045 20.3 22.0 0.0018 18.4 12.3 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46481.1 - 0.00051 20.6 8.9 0.00051 20.6 8.9 2.8 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46481.1 - 0.00077 19.2 14.7 0.0033 17.2 1.2 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 KKK46481.1 - 0.0037 17.3 1.0 0.0037 17.3 1.0 3.7 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 KKK46481.1 - 0.005 16.9 10.1 0.005 16.9 10.1 3.3 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 KKK46481.1 - 0.009 15.8 0.3 0.009 15.8 0.3 2.8 4 0 0 4 4 4 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_18 PF13746.6 KKK46481.1 - 0.019 15.2 0.8 0.019 15.2 0.8 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46481.1 - 1.2 10.2 19.0 1.2 10.1 12.6 3.4 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 KKK46481.1 - 2.3 9.1 19.6 2 9.3 2.0 4.5 4 1 0 4 4 4 0 4Fe-4S dicluster domain Pneumo_M2 PF07380.11 KKK46482.1 - 0.00028 21.1 0.2 0.00029 21.0 0.2 1.1 1 0 0 1 1 1 1 Pneumovirus M2 protein RPA_interact_C PF14768.6 KKK46482.1 - 0.005 17.4 0.3 0.0054 17.3 0.3 1.1 1 0 0 1 1 1 1 Replication protein A interacting C-terminal zf-TFIIIC PF12660.7 KKK46482.1 - 0.047 13.7 0.1 0.051 13.5 0.1 1.1 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-FPG_IleRS PF06827.14 KKK46482.1 - 0.11 12.4 0.9 0.24 11.3 0.9 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS TMEM40 PF15817.5 KKK46485.1 - 1.1 9.0 9.5 0.073 12.8 3.3 2.2 1 1 0 2 2 2 0 Transmembrane protein 40 family zf-PARP PF00645.18 KKK46486.1 - 0.025 15.4 0.0 0.027 15.3 0.0 1.0 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CoiA PF06054.11 KKK46487.1 - 7.5e-13 48.4 4.6 2.6e-12 46.6 4.5 1.7 1 1 0 1 1 1 1 Competence protein CoiA-like family Sua5_yciO_yrdC PF01300.18 KKK46491.1 - 4.9e-41 140.2 0.0 7.8e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination HypF_C PF17788.1 KKK46491.1 - 6.3e-27 94.3 2.6 7.7e-27 94.0 1.4 1.8 2 0 0 2 2 2 1 HypF Kae1-like domain zf-HYPF PF07503.12 KKK46491.1 - 7e-24 83.3 8.9 3.8e-12 45.8 1.0 2.7 2 0 0 2 2 2 2 HypF finger Acylphosphatase PF00708.18 KKK46491.1 - 4.2e-19 68.7 0.0 8.5e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Acylphosphatase LIM PF00412.22 KKK46491.1 - 0.33 11.2 5.8 0.29 11.4 1.4 2.5 1 1 1 2 2 2 0 LIM domain HypD PF01924.16 KKK46492.1 - 3.1e-143 477.1 0.0 3.6e-143 476.9 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family AIRS_C PF02769.22 KKK46493.1 - 6.4e-27 94.6 0.0 9.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KKK46493.1 - 1.3e-15 57.8 0.4 2.6e-15 56.8 0.4 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Oxidored_q6 PF01058.22 KKK46494.1 - 0.0006 19.6 0.0 0.00068 19.5 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit N6_Mtase PF02384.16 KKK46497.1 - 1e-05 25.0 2.5 6.1e-05 22.4 0.4 2.1 2 0 0 2 2 2 1 N-6 DNA Methylase Eco57I PF07669.11 KKK46497.1 - 0.00044 20.7 0.7 0.00044 20.7 0.7 2.1 2 0 0 2 2 2 1 Eco57I restriction-modification methylase Integrin_alpha PF00357.20 KKK46497.1 - 0.062 13.3 0.6 0.23 11.5 0.6 2.1 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region PepX_C PF08530.10 KKK46498.1 - 5.4e-38 131.2 0.0 8.1e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KKK46498.1 - 1.7e-34 119.7 2.6 1.7e-32 113.1 2.6 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) HpaB_N PF11794.8 KKK46499.1 - 3.8e-73 246.5 0.0 5.4e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HpaB PF03241.13 KKK46499.1 - 5.7e-37 126.8 0.0 8.5e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal DUF4580 PF15162.6 KKK46499.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) Acyl-CoA_dh_M PF02770.19 KKK46499.1 - 0.038 14.2 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Dynein_AAA_lid PF17852.1 KKK46499.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Methyltransf_23 PF13489.6 KKK46500.1 - 1.7e-07 31.3 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KKK46500.1 - 1.2e-06 29.1 0.0 1.6e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KKK46500.1 - 2.1e-06 28.3 0.0 3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KKK46500.1 - 0.00031 20.6 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KKK46500.1 - 0.0012 19.6 0.0 0.0034 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NYN PF01936.18 KKK46500.1 - 0.0052 17.3 0.0 0.0061 17.1 0.0 1.2 1 0 0 1 1 1 1 NYN domain Methyltransf_9 PF08003.11 KKK46500.1 - 0.006 15.5 0.0 0.0071 15.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) DUF1700 PF08006.11 KKK46501.1 - 0.00011 21.8 4.3 0.00011 21.8 4.3 2.8 2 2 0 2 2 2 1 Protein of unknown function (DUF1700) Nup88 PF10168.9 KKK46501.1 - 0.087 10.6 0.2 0.12 10.2 0.2 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF2631 PF10939.8 KKK46501.1 - 0.14 12.1 3.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) DUF4191 PF13829.6 KKK46501.1 - 0.29 10.5 7.1 5.1 6.4 5.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) YfzA PF14118.6 KKK46501.1 - 0.55 10.7 0.0 0.55 10.7 0.0 3.0 3 1 0 4 4 4 0 YfzA-like protein PadR PF03551.14 KKK46502.1 - 1.6e-19 69.6 1.1 3.1e-19 68.7 0.5 1.8 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family HxlR PF01638.17 KKK46502.1 - 0.00018 21.3 0.1 0.00034 20.4 0.1 1.5 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 KKK46502.1 - 0.00032 20.8 0.1 0.001 19.2 0.1 1.9 1 1 0 1 1 1 1 Winged helix DNA-binding domain HTH_27 PF13463.6 KKK46502.1 - 0.044 14.3 0.4 0.47 11.0 0.2 2.6 1 1 1 2 2 2 0 Winged helix DNA-binding domain zf-piccolo PF05715.13 KKK46502.1 - 0.21 11.8 1.4 3.8 7.7 1.4 2.5 1 1 0 1 1 1 0 Piccolo Zn-finger DUF998 PF06197.13 KKK46504.1 - 1.1e-07 31.7 8.9 0.0022 17.6 5.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF998) DUF2975 PF11188.8 KKK46504.1 - 0.0037 17.1 1.9 0.0037 17.1 1.9 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2975) FtsX PF02687.21 KKK46504.1 - 0.031 14.7 2.2 0.031 14.7 2.2 2.8 2 1 0 2 2 2 0 FtsX-like permease family DUF2207 PF09972.9 KKK46504.1 - 0.3 9.8 10.7 1 8.0 0.8 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) QueC PF06508.13 KKK46505.1 - 8.7e-06 25.4 0.0 0.0028 17.2 0.0 2.3 2 0 0 2 2 2 2 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KKK46505.1 - 7.1e-05 22.0 0.0 0.00029 20.0 0.0 1.9 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 KKK46505.1 - 0.00053 18.9 0.0 0.0087 14.9 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.20 KKK46505.1 - 0.0026 17.6 0.0 0.0064 16.3 0.0 1.7 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.21 KKK46505.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase AIRS_C PF02769.22 KKK46506.1 - 3.5e-13 50.0 0.1 5.7e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GHMP_kinases_C PF08544.13 KKK46508.1 - 3.3e-07 30.6 0.0 7.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4296 PF14129.6 KKK46508.1 - 0.077 13.6 0.4 0.17 12.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) DHNA PF04038.12 KKK46509.1 - 1.2e-32 112.6 0.0 1.4e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase DUF447 PF04289.12 KKK46510.1 - 3.1e-22 79.2 1.5 8.9e-22 77.7 1.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF447) Radical_SAM PF04055.21 KKK46511.1 - 2.1e-17 64.0 0.6 3e-16 60.3 0.6 2.3 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 KKK46511.1 - 1.7e-10 41.3 10.9 4e-09 36.9 10.9 2.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_6 PF12837.7 KKK46511.1 - 1.2e-08 34.7 8.3 0.00094 19.2 0.9 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 KKK46511.1 - 2.4e-08 33.5 8.4 0.00023 20.8 0.9 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK46511.1 - 1.1e-06 29.5 5.4 0.0018 19.1 0.2 2.8 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 KKK46511.1 - 1.4e-05 25.5 10.3 1.4e-05 25.5 10.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46511.1 - 7.2e-05 22.9 13.9 7.2e-05 22.9 13.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 KKK46511.1 - 0.00019 21.7 13.8 0.1 13.1 1.5 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 KKK46511.1 - 0.0008 19.5 17.2 0.0011 19.0 2.3 2.8 3 1 0 3 3 2 2 4Fe-4S dicluster domain Fer4_14 PF13394.6 KKK46511.1 - 0.0025 17.9 0.6 0.0025 17.9 0.6 2.5 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 KKK46511.1 - 0.01 15.9 14.5 0.01 15.9 14.5 2.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK46511.1 - 0.04 14.0 19.0 0.043 13.9 2.0 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK46511.1 - 0.23 12.0 13.6 3.1 8.4 3.5 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 KKK46511.1 - 0.45 10.7 11.6 0.23 11.7 9.2 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Isochorismatase PF00857.20 KKK46512.1 - 1.3e-37 129.7 0.0 1.5e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF1694 PF07997.11 KKK46512.1 - 0.096 12.8 0.4 0.16 12.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) Rubrerythrin PF02915.17 KKK46513.1 - 4e-10 40.2 4.2 1e-09 38.9 4.2 1.6 1 1 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 KKK46513.1 - 0.0064 16.8 0.9 0.023 15.0 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) Ferritin_2 PF13668.6 KKK46513.1 - 0.008 16.4 1.3 2.4 8.3 0.1 2.3 1 1 1 2 2 2 2 Ferritin-like domain TF_Zn_Ribbon PF08271.12 KKK46513.1 - 0.14 11.7 2.3 0.44 10.1 2.3 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding YabA PF06156.13 KKK46513.1 - 0.14 12.8 4.7 1.8 9.2 0.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF3039 PF11238.8 KKK46513.1 - 0.14 11.9 0.8 0.29 10.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) HypA PF01155.19 KKK46513.1 - 0.22 11.5 2.7 0.24 11.5 0.5 2.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1464 PF07318.12 KKK46514.1 - 3.1e-94 315.8 1.3 3.6e-94 315.6 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1464) Acetate_kinase PF00871.17 KKK46514.1 - 0.00026 19.8 1.0 0.00047 19.0 0.6 1.6 2 0 0 2 2 2 1 Acetokinase family Pterin_bind PF00809.22 KKK46515.1 - 1.7e-06 27.9 0.1 3.2e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 Pterin binding enzyme NusA_N PF08529.11 KKK46515.1 - 0.079 13.3 0.2 0.096 13.0 0.2 1.3 1 0 0 1 1 1 0 NusA N-terminal domain Peptidase_M54 PF07998.11 KKK46519.1 - 1.2e-20 74.4 1.2 2e-20 73.6 1.2 1.6 1 1 0 1 1 1 1 Peptidase family M54 Oxidored_FMN PF00724.20 KKK46520.1 - 3.5e-35 121.9 0.0 5.1e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KKK46520.1 - 0.00012 21.3 0.1 0.0012 18.0 0.0 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.6 KKK46520.1 - 0.06 12.8 0.4 0.13 11.7 0.1 1.6 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Glycos_transf_1 PF00534.20 KKK46521.1 - 2.2e-33 115.2 0.1 3.2e-33 114.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KKK46521.1 - 1.3e-20 74.2 0.0 5.1e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KKK46521.1 - 9.8e-14 51.7 0.1 1.5e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KKK46521.1 - 7.6e-07 29.4 0.0 1.7e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KKK46521.1 - 0.01 16.3 0.0 0.075 13.5 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain MCH PF02289.16 KKK46524.1 - 1.1e-105 353.4 0.1 1.2e-105 353.3 0.1 1.0 1 0 0 1 1 1 1 Cyclohydrolase (MCH) DHHA1 PF02272.19 KKK46525.1 - 1.7e-07 31.7 0.2 8.4e-07 29.5 0.0 2.3 1 1 1 2 2 2 1 DHHA1 domain CDC45 PF02724.14 KKK46525.1 - 0.062 11.6 0.0 0.097 10.9 0.0 1.3 1 0 0 1 1 1 0 CDC45-like protein RMMBL PF07521.12 KKK46526.1 - 0.0002 21.2 0.0 0.00026 20.9 0.0 1.3 1 1 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CCG PF02754.16 KKK46529.1 - 1e-29 102.5 2.6 1.5e-17 63.6 0.1 2.6 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 KKK46529.1 - 8.6e-10 38.9 5.1 8.6e-10 38.9 5.1 2.8 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46529.1 - 1.9e-09 37.9 6.6 1.9e-09 37.9 6.6 2.6 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46529.1 - 4.4e-09 36.8 4.5 4.4e-09 36.8 4.5 3.4 4 0 0 4 4 3 1 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46529.1 - 1.2e-06 28.0 17.6 0.00036 20.2 3.8 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 KKK46529.1 - 4.7e-06 26.7 8.2 4.8e-06 26.6 4.2 3.0 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46529.1 - 5.8e-06 27.2 7.7 1.7e-05 25.7 5.5 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 KKK46529.1 - 1e-05 25.6 23.1 5.3e-05 23.2 11.3 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK46529.1 - 0.00017 21.5 10.4 0.0042 17.1 1.2 3.9 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_18 PF13746.6 KKK46529.1 - 0.0063 16.7 8.1 0.12 12.6 7.4 2.7 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK46529.1 - 0.0082 16.3 10.6 0.16 12.1 0.6 3.3 4 0 0 4 4 4 2 4Fe-4S dicluster domain Desulfoferrod_N PF06397.12 KKK46529.1 - 0.01 15.4 0.5 0.01 15.4 0.5 3.1 4 0 0 4 4 2 0 Desulfoferrodoxin, N-terminal domain Fer4_4 PF12800.7 KKK46529.1 - 0.052 14.1 2.3 0.052 14.1 2.3 3.8 4 0 0 4 4 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK46529.1 - 0.8 10.3 6.6 16 6.2 0.2 2.9 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 KKK46529.1 - 3.8 8.3 6.4 6.5 7.6 0.3 3.0 3 0 0 3 3 2 0 4Fe-4S single cluster domain DUF4064 PF13273.6 KKK46533.1 - 0.013 15.8 3.3 0.016 15.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2975 PF11188.8 KKK46533.1 - 0.054 13.4 3.7 2.5 8.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) LapA_dom PF06305.11 KKK46533.1 - 0.3 10.9 10.5 0.26 11.1 3.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 KKK46533.1 - 0.36 9.5 6.7 0.39 9.4 6.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_1 PF00561.20 KKK46535.1 - 8.7e-19 68.2 0.0 3.5e-14 53.1 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KKK46535.1 - 6.2e-15 56.4 0.0 7.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KKK46535.1 - 2.1e-08 33.8 0.0 4e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KKK46535.1 - 1.4e-05 24.0 0.0 5e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Ndr family Thioesterase PF00975.20 KKK46535.1 - 0.00053 20.2 0.0 0.0061 16.7 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S15 PF02129.18 KKK46535.1 - 0.039 13.5 0.0 0.33 10.5 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KKK46535.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short PF00106.25 KKK46536.1 - 1.3e-48 165.1 0.3 1.6e-48 164.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KKK46536.1 - 6.8e-40 137.1 0.1 8.2e-40 136.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KKK46536.1 - 3e-07 30.5 0.4 5.5e-07 29.7 0.4 1.4 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KKK46536.1 - 7.4e-05 22.7 0.3 0.00011 22.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KKK46536.1 - 0.0073 15.8 0.4 0.011 15.2 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KKK46536.1 - 0.025 14.4 0.1 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.18 KKK46536.1 - 0.039 14.2 0.3 0.057 13.7 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain HATPase_c PF02518.26 KKK46537.1 - 3.1e-19 69.5 0.3 1.7e-18 67.2 0.1 2.2 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 KKK46537.1 - 0.00015 21.6 0.1 0.00043 20.1 0.1 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 KKK46537.1 - 0.00072 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Wzy_C PF04932.15 KKK46537.1 - 0.14 11.8 1.3 0.24 11.0 1.3 1.3 1 0 0 1 1 1 0 O-Antigen ligase Response_reg PF00072.24 KKK46538.1 - 2.5e-23 82.4 0.0 2.8e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain tRNA-synt_1e PF01406.19 KKK46539.1 - 6e-104 347.6 2.3 9.3e-104 347.0 2.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 KKK46539.1 - 3.3e-16 59.5 1.7 1.6e-15 57.3 1.0 2.4 3 0 0 3 3 3 1 DALR domain tRNA-synt_1g PF09334.11 KKK46539.1 - 3.3e-14 52.5 1.6 7.5e-07 28.2 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KKK46539.1 - 1.6e-09 36.6 0.1 5.3e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 KKK46539.1 - 0.00013 21.0 0.1 0.0042 16.1 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) DUF5089 PF17002.5 KKK46539.1 - 0.0083 16.0 3.4 0.3 10.9 0.6 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5089) DUF1366 PF07104.11 KKK46539.1 - 0.8 9.4 9.2 1.7 8.4 1.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1366) DUF4064 PF13273.6 KKK46540.1 - 0.00087 19.5 1.6 0.0009 19.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Gram_pos_anchor PF00746.21 KKK46540.1 - 7.8 6.5 7.4 35 4.5 6.1 2.2 1 1 1 2 2 2 0 LPXTG cell wall anchor motif Ras PF00071.22 KKK46541.1 - 6.7e-50 168.8 0.4 7.6e-50 168.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KKK46541.1 - 3e-29 101.7 0.1 4.7e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KKK46541.1 - 1.6e-16 60.2 0.2 2e-16 59.9 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KKK46541.1 - 6.3e-06 25.7 0.2 8.4e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KKK46541.1 - 3e-05 24.1 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KKK46541.1 - 0.011 15.7 0.1 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 KKK46541.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KKK46541.1 - 0.03 14.7 0.0 0.033 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KKK46541.1 - 0.035 13.6 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF296 PF03479.15 KKK46542.1 - 5e-23 81.5 0.1 5.7e-23 81.3 0.1 1.0 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain CCG PF02754.16 KKK46547.1 - 5.1e-26 90.7 4.8 7.6e-18 64.5 0.9 3.5 4 0 0 4 4 3 2 Cysteine-rich domain Pyr_redox_2 PF07992.14 KKK46547.1 - 2.5e-25 89.3 0.1 3.9e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KKK46547.1 - 1.1e-22 79.9 22.7 7e-20 70.9 0.2 4.4 3 1 1 4 4 4 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KKK46547.1 - 1.7e-09 37.8 0.1 4.2e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KKK46547.1 - 6.7e-08 32.1 0.0 0.0019 17.5 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.6 KKK46547.1 - 5.7e-07 29.5 4.7 5.7e-07 29.5 4.7 4.5 4 0 0 4 4 4 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 KKK46547.1 - 7.3e-07 29.7 0.7 0.0026 18.3 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_17 PF13534.6 KKK46547.1 - 1.4e-06 28.7 4.2 1.4e-06 28.7 4.2 4.8 5 2 1 6 6 4 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46547.1 - 3e-06 27.3 4.7 3e-06 27.3 4.7 4.2 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK46547.1 - 7e-05 23.2 8.8 7e-05 23.2 8.8 4.8 4 1 1 5 5 5 2 4Fe-4S dicluster domain FAD_binding_2 PF00890.24 KKK46547.1 - 0.00011 21.4 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KKK46547.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KKK46547.1 - 0.00015 21.1 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Fer4_7 PF12838.7 KKK46547.1 - 0.00015 22.3 21.0 0.00042 20.8 10.0 5.0 3 2 2 5 5 4 2 4Fe-4S dicluster domain DAO PF01266.24 KKK46547.1 - 0.00039 20.1 0.1 0.0008 19.1 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KKK46547.1 - 0.001 18.5 0.0 0.037 13.3 0.0 2.4 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KKK46547.1 - 0.0012 18.3 0.1 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KKK46547.1 - 0.0012 18.0 0.2 0.0022 17.2 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KKK46547.1 - 0.0019 16.9 0.1 0.0032 16.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FMO-like PF00743.19 KKK46547.1 - 0.0023 16.4 0.0 0.012 14.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Fer4_21 PF14697.6 KKK46547.1 - 0.003 17.6 0.5 0.003 17.6 0.5 5.1 6 0 0 6 6 3 2 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 KKK46547.1 - 0.014 14.7 0.1 0.36 10.1 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_18 PF13746.6 KKK46547.1 - 0.015 15.5 13.3 0.054 13.7 0.4 4.5 4 0 0 4 4 4 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KKK46547.1 - 0.029 15.3 10.5 0.029 15.3 10.5 5.4 5 2 1 6 6 4 0 4Fe-4S double cluster binding domain 2-Hacid_dh_C PF02826.19 KKK46547.1 - 0.099 12.0 0.2 17 4.7 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AFOR_C PF01314.18 KKK46548.1 - 4.9e-94 315.5 0.0 6.1e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK46548.1 - 6.1e-64 215.6 0.0 9.6e-64 214.9 0.0 1.3 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain Fer4_11 PF13247.6 KKK46549.1 - 4.4e-11 42.8 11.5 4.4e-11 42.8 11.5 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46549.1 - 8.2e-11 42.3 23.3 6.3e-05 23.5 10.9 3.7 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46549.1 - 5.8e-10 39.2 22.8 0.00012 22.2 9.7 3.1 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK46549.1 - 1.3e-09 37.7 40.4 4.1e-05 23.5 2.5 4.8 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_10 PF13237.6 KKK46549.1 - 1.8e-08 34.4 24.1 5.4e-06 26.4 6.6 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46549.1 - 5e-08 32.4 41.1 0.00014 21.5 3.0 4.9 6 0 0 6 6 5 4 4Fe-4S binding domain Fer4_16 PF13484.6 KKK46549.1 - 9.8e-06 26.4 27.7 0.21 12.5 0.1 4.5 2 1 1 4 4 4 3 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 KKK46549.1 - 1.6e-05 24.7 34.5 0.00071 19.5 2.3 4.7 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_4 PF12800.7 KKK46549.1 - 0.00014 22.1 34.0 0.025 15.1 2.4 4.5 5 0 0 5 5 4 4 4Fe-4S binding domain Fer4_21 PF14697.6 KKK46549.1 - 0.00058 19.9 27.4 0.038 14.1 10.9 3.9 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 KKK46549.1 - 0.0025 18.6 35.3 0.42 11.6 4.7 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Ta0938 PF11494.8 KKK46549.1 - 0.018 15.3 1.8 0.026 14.8 0.0 2.0 1 1 1 2 2 2 0 Ta0938 Fer4_15 PF13459.6 KKK46549.1 - 0.097 13.4 24.7 0.31 11.8 7.7 3.4 2 2 0 2 2 2 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 KKK46549.1 - 0.3 11.7 27.2 2.8 8.5 3.4 4.0 2 2 2 4 4 4 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 KKK46549.1 - 0.69 10.4 26.6 0.088 13.3 8.9 3.1 2 2 0 2 2 2 0 4Fe-4S dicluster domain Oxidored_FMN PF00724.20 KKK46550.1 - 2e-80 270.7 0.0 2.4e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cupin_2 PF07883.11 KKK46551.1 - 3.2e-12 46.0 0.0 4.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KKK46551.1 - 1.8e-07 30.7 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KKK46551.1 - 1.4e-05 24.8 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 KKK46551.1 - 3.2e-05 23.6 0.1 3.5e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 KKK46551.1 - 9.4e-05 22.6 0.1 0.00011 22.4 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family EutQ PF06249.12 KKK46551.1 - 0.002 17.9 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.7 KKK46551.1 - 0.0054 16.5 0.0 0.0058 16.4 0.0 1.1 1 0 0 1 1 1 1 Cupin DMSP_lyase PF16867.5 KKK46551.1 - 0.036 13.7 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase CENP-C_C PF11699.8 KKK46551.1 - 0.038 14.2 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like OGG_N PF07934.12 KKK46551.1 - 0.054 13.6 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Pirin_C PF05726.13 KKK46551.1 - 0.12 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Pirin C-terminal cupin domain GPI PF06560.11 KKK46551.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) LRR_8 PF13855.6 KKK46552.1 - 1.4e-25 88.8 24.6 1.6e-11 43.7 3.5 4.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KKK46552.1 - 7.7e-16 57.9 32.9 1.3e-06 28.6 1.7 5.4 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KKK46552.1 - 5.5e-08 32.5 10.2 0.00054 19.5 0.2 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 KKK46552.1 - 8.9e-05 22.5 5.1 0.0068 16.4 0.2 2.5 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 KKK46552.1 - 0.00032 20.7 0.4 32 4.7 0.0 5.0 2 2 2 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain DUF5465 PF17553.2 KKK46552.1 - 0.0023 18.2 0.7 0.066 13.7 0.1 3.4 3 0 0 3 3 3 1 Family of unknown function (DUF5465) LRR_1 PF00560.33 KKK46552.1 - 0.0075 16.7 26.4 0.13 12.8 0.2 7.5 6 2 1 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 KKK46552.1 - 0.026 14.6 15.9 0.077 13.1 0.2 5.6 5 0 0 5 5 5 0 Leucine Rich repeat CREPT PF16566.5 KKK46552.1 - 0.026 14.7 1.7 9.5 6.4 0.0 3.9 1 1 2 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour LRR_2 PF07723.13 KKK46552.1 - 0.43 11.3 2.3 55 4.7 0.0 4.3 6 0 0 6 6 6 0 Leucine Rich Repeat Fe-ADH PF00465.19 KKK46555.1 - 3.4e-85 286.0 0.0 3.8e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KKK46555.1 - 5.2e-16 59.1 0.0 3e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase AFOR_C PF01314.18 KKK46556.1 - 1.4e-91 307.4 0.0 1.8e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 AFOR_N PF02730.15 KKK46556.1 - 1.2e-66 224.4 0.1 2.7e-66 223.2 0.0 1.6 2 0 0 2 2 2 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain NAD_binding_8 PF13450.6 KKK46557.1 - 7.3e-09 35.7 0.0 1.2e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KKK46557.1 - 4.5e-07 29.3 0.4 6.4e-07 28.8 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KKK46557.1 - 9.9e-07 28.3 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KKK46557.1 - 2.1e-06 27.3 0.1 3.9e-06 26.5 0.1 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KKK46557.1 - 2.5e-06 27.3 0.5 4.1e-06 26.6 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KKK46557.1 - 8e-05 23.1 0.1 0.0022 18.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KKK46557.1 - 8.5e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 KKK46557.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KKK46557.1 - 0.00015 20.6 0.2 0.00026 19.8 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KKK46557.1 - 0.0002 20.7 0.1 0.00064 19.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KKK46557.1 - 0.00022 20.6 0.3 0.00044 19.6 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KKK46557.1 - 0.00063 18.9 0.2 0.001 18.3 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KKK46557.1 - 0.0031 16.8 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KKK46557.1 - 0.049 13.6 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KKK46557.1 - 0.053 14.0 0.0 0.33 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding MCRA PF06100.11 KKK46557.1 - 0.063 12.1 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 MCRA family DbpA PF03880.15 KKK46557.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain Lycopene_cycl PF05834.12 KKK46557.1 - 0.094 11.7 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4 PF00037.27 KKK46558.1 - 1.6e-17 62.5 40.0 5.8e-06 25.9 3.8 4.5 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_16 PF13484.6 KKK46558.1 - 1.6e-14 54.6 23.6 0.0019 19.1 1.8 4.5 4 0 0 4 4 4 4 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KKK46558.1 - 2.7e-14 53.0 27.2 2.3e-06 27.6 10.2 3.6 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46558.1 - 5.9e-13 49.2 38.1 5.5e-06 26.9 13.4 4.6 3 2 2 6 6 6 5 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46558.1 - 3.7e-12 46.2 34.9 2.1e-07 31.0 10.3 3.3 3 1 1 4 4 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KKK46558.1 - 5.2e-11 42.5 32.0 3.4e-05 23.9 12.7 4.0 2 2 2 4 4 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK46558.1 - 1.3e-10 40.7 34.4 0.00034 20.5 3.0 4.6 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_17 PF13534.6 KKK46558.1 - 1.7e-10 41.3 16.0 6.6e-05 23.4 4.3 3.6 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK46558.1 - 6.6e-10 38.6 50.6 0.0013 18.7 2.2 4.7 5 0 0 5 5 4 4 4Fe-4S binding domain Fer4_4 PF12800.7 KKK46558.1 - 2.2e-08 34.0 32.2 0.0087 16.5 1.1 4.6 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_8 PF13183.6 KKK46558.1 - 3.2e-08 33.9 23.9 8.3e-05 23.0 7.4 4.3 4 1 1 5 5 5 4 4Fe-4S dicluster domain Fer4_15 PF13459.6 KKK46558.1 - 3.8e-05 24.3 21.2 0.2 12.4 0.4 4.5 4 0 0 4 4 4 3 4Fe-4S single cluster domain Fer4_13 PF13370.6 KKK46558.1 - 0.0029 18.1 28.3 0.35 11.4 1.3 4.5 4 0 0 4 4 4 3 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KKK46558.1 - 0.0057 17.5 52.5 0.03 15.3 6.0 5.0 5 0 0 5 5 4 4 4Fe-4S binding domain Rubi_NSP_C PF12601.8 KKK46558.1 - 0.043 13.9 0.0 5 7.3 0.0 2.4 2 0 0 2 2 2 0 Rubivirus non-structural protein Fer4_22 PF17179.4 KKK46558.1 - 0.054 14.3 26.2 0.13 13.1 1.1 4.5 3 1 2 5 5 5 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KKK46558.1 - 0.18 12.0 22.1 4.6 7.5 0.7 4.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain FlpD PF02662.16 KKK46559.1 - 5.7e-11 42.5 0.1 5.9e-11 42.4 0.1 1.0 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit FlpD PF02662.16 KKK46560.1 - 0.0009 19.2 0.0 0.0011 19.0 0.0 1.1 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit FrhB_FdhB_C PF04432.13 KKK46561.1 - 2.3e-11 43.8 4.7 2.6e-10 40.3 0.0 2.5 1 1 1 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Fer4_10 PF13237.6 KKK46561.1 - 1.4e-07 31.5 10.6 0.0002 21.4 0.1 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 KKK46561.1 - 2.5e-07 31.1 17.2 2.5e-07 31.1 17.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KKK46561.1 - 1.2e-06 28.2 18.8 0.0011 18.9 4.2 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 KKK46561.1 - 6.8e-05 23.2 16.9 6.8e-05 23.2 16.9 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KKK46561.1 - 0.00018 22.0 20.4 0.00018 22.0 18.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 KKK46561.1 - 0.00055 20.0 20.6 0.0056 16.8 18.4 3.0 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 KKK46561.1 - 0.0018 18.0 15.8 0.0031 17.3 3.4 3.2 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 KKK46561.1 - 0.046 14.6 18.8 0.32 12.0 3.3 2.9 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 KKK46561.1 - 0.071 13.3 11.3 0.5 10.6 2.1 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain FrhB_FdhB_N PF04422.13 KKK46561.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Fer4_22 PF17179.4 KKK46561.1 - 0.14 13.0 22.4 0.34 11.8 1.6 2.8 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KKK46561.1 - 1.6 8.9 25.2 21 5.4 12.1 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 KKK46561.1 - 2.2 8.5 30.5 0.08 13.1 4.3 3.5 3 1 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 KKK46561.1 - 2.3 8.8 17.2 8.5 7.0 5.2 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Molybdopterin PF00384.22 KKK46562.1 - 3.7e-30 105.3 0.0 5.4e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 KKK46562.1 - 1e-09 38.4 0.0 2.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain RHH_1 PF01402.21 KKK46563.1 - 2.7e-05 23.9 0.0 5.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family ProQ PF04352.13 KKK46563.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 ProQ/FINO family RHH_8 PF17723.1 KKK46563.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family TPR_1 PF00515.28 KKK46565.1 - 2.8e-46 153.5 20.0 1.9e-11 43.2 0.1 6.8 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 KKK46565.1 - 1.5e-38 130.2 5.1 4.9e-11 42.1 0.2 4.3 2 1 2 4 4 4 4 TPR repeat TPR_2 PF07719.17 KKK46565.1 - 3.7e-38 126.6 12.2 9.3e-09 34.7 0.0 6.2 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KKK46565.1 - 4.2e-35 117.0 11.7 1.7e-07 30.9 0.0 6.0 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 KKK46565.1 - 2e-27 93.6 5.1 1.5e-05 25.0 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 KKK46565.1 - 1.7e-20 72.2 0.0 5.2e-06 26.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KKK46565.1 - 1.9e-20 73.1 0.0 5.6e-08 33.2 0.0 4.0 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KKK46565.1 - 1.4e-19 68.6 1.4 7.7e-05 22.5 0.0 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KKK46565.1 - 3e-19 69.1 1.3 1.9e-07 31.2 0.0 4.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KKK46565.1 - 7.3e-19 66.9 0.0 0.00043 20.9 0.0 5.2 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 KKK46565.1 - 1.6e-18 67.1 0.0 1.6e-07 31.8 0.0 3.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 KKK46565.1 - 2.6e-17 62.7 0.0 4.6e-05 23.5 0.0 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KKK46565.1 - 1.1e-12 47.4 6.0 0.016 15.0 0.0 6.1 5 2 1 6 6 6 3 Tetratricopeptide repeat ChAPs PF09295.10 KKK46565.1 - 1.7e-08 33.9 0.1 0.0088 15.1 0.0 3.1 1 1 2 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 KKK46565.1 - 1.5e-06 27.6 0.0 0.38 9.9 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 KKK46565.1 - 3e-06 27.3 0.1 0.53 10.4 0.0 3.6 2 2 2 4 4 4 1 Rapsyn N-terminal myristoylation and linker region ANAPC3 PF12895.7 KKK46565.1 - 0.00012 22.2 1.8 0.056 13.7 0.1 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KKK46565.1 - 0.00016 21.7 1.7 0.038 14.1 0.1 2.9 4 0 0 4 4 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KKK46565.1 - 0.00019 21.7 0.0 7 7.1 0.0 3.6 1 1 3 4 4 4 0 Tetratricopeptide repeat DUF5588 PF17826.1 KKK46565.1 - 0.00022 20.3 0.0 0.031 13.2 0.0 2.1 1 1 1 2 2 2 1 Family of unknown function (DUF5588) SNAP PF14938.6 KKK46565.1 - 0.00022 20.8 2.2 0.038 13.4 0.3 2.8 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP DUF4919 PF16266.5 KKK46565.1 - 0.0013 18.7 0.0 0.18 11.8 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4919) DUF627 PF04781.12 KKK46565.1 - 0.0033 17.4 0.0 5.3 7.1 0.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF627) TOM20_plant PF06552.12 KKK46565.1 - 0.0057 16.4 4.2 0.63 9.8 0.2 4.5 1 1 3 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 BTAD PF03704.17 KKK46565.1 - 0.0079 16.6 0.0 0.046 14.2 0.0 1.9 1 1 0 2 2 2 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KKK46565.1 - 0.022 13.7 1.1 0.79 8.5 0.3 2.5 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 APOBEC_C PF05240.14 KKK46565.1 - 0.027 14.4 1.3 0.92 9.5 0.0 3.0 2 1 1 3 3 3 0 APOBEC-like C-terminal domain NAD2 PF18782.1 KKK46565.1 - 0.029 14.5 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 MIT PF04212.18 KKK46565.1 - 0.032 14.3 6.6 11 6.2 0.1 5.1 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 KKK46565.1 - 0.042 14.3 0.2 0.64 10.5 0.1 2.4 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation Rubis-subs-bind PF09273.11 KKK46565.1 - 0.053 14.2 0.0 0.079 13.7 0.0 1.3 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding Wzy_C_2 PF11846.8 KKK46565.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF3856 PF12968.7 KKK46565.1 - 0.058 13.5 0.1 3.2 7.8 0.0 2.7 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 KKK46565.1 - 0.066 13.9 3.5 12 6.8 0.1 4.1 4 0 0 4 4 4 0 Sel1 repeat FAT PF02259.23 KKK46565.1 - 0.095 11.9 6.0 4.4 6.4 1.4 3.1 1 1 1 2 2 2 0 FAT domain PPR PF01535.20 KKK46565.1 - 0.19 12.1 10.9 17 5.9 0.1 5.0 6 0 0 6 6 4 0 PPR repeat TPR_MalT PF17874.1 KKK46565.1 - 0.24 10.7 0.0 6.3 6.1 0.0 2.8 2 1 0 2 2 2 0 MalT-like TPR region NSF PF02071.20 KKK46565.1 - 1.1 10.4 6.9 58 5.2 0.1 4.9 5 0 0 5 5 4 0 Aromatic-di-Alanine (AdAR) repeat IQ PF00612.27 KKK46566.1 - 0.05 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Radical_SAM PF04055.21 KKK46566.1 - 0.082 13.3 0.0 0.32 11.4 0.0 2.0 2 1 0 2 2 2 0 Radical SAM superfamily Bac_luciferase PF00296.20 KKK46567.1 - 2.2e-49 168.6 0.0 5.9e-49 167.2 0.0 1.5 1 1 1 2 2 2 1 Luciferase-like monooxygenase Radical_SAM PF04055.21 KKK46567.1 - 0.018 15.4 0.2 0.14 12.5 0.1 2.3 2 1 0 2 2 2 0 Radical SAM superfamily WD40_alt PF14077.6 KKK46567.1 - 0.11 12.4 4.6 2.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif ZapB PF06005.12 KKK46567.1 - 0.5 10.8 3.0 0.91 10.0 1.4 2.2 2 1 1 3 3 3 0 Cell division protein ZapB Glucos_trans_II PF14264.6 KKK46568.1 - 0.00045 19.7 6.5 0.00049 19.6 6.5 1.0 1 0 0 1 1 1 1 Glucosyl transferase GtrII 7TMR-DISM_7TM PF07695.11 KKK46568.1 - 0.023 14.6 6.9 0.028 14.3 6.9 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling FUSC PF04632.12 KKK46568.1 - 0.6 8.6 2.8 0.77 8.2 2.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4386 PF14329.6 KKK46569.1 - 0.056 13.3 4.2 0.041 13.8 2.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) DUF3043 PF11241.8 KKK46569.1 - 0.43 10.6 1.3 0.54 10.3 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Rho_N PF07498.12 KKK46573.1 - 1e-06 28.5 0.6 4.5e-06 26.5 0.0 2.5 3 0 0 3 3 3 1 Rho termination factor, N-terminal domain BOF PF04076.13 KKK46573.1 - 0.002 18.2 1.8 0.004 17.2 1.8 1.5 1 0 0 1 1 1 1 Bacterial OB fold (BOF) protein SAP PF02037.27 KKK46573.1 - 0.016 15.0 0.0 0.049 13.4 0.0 1.9 1 0 0 1 1 1 0 SAP domain EFP_N PF08207.12 KKK46573.1 - 0.059 13.4 0.5 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain YojJ PF10372.9 KKK46573.1 - 0.072 13.2 0.2 0.55 10.4 0.1 2.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Lipase_2 PF01674.18 KKK46574.1 - 1.3e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Palm_thioest PF02089.15 KKK46574.1 - 8.3e-07 29.1 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 KKK46574.1 - 0.00016 21.0 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KKK46574.1 - 0.00033 20.4 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KKK46574.1 - 0.0023 17.7 0.0 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KKK46574.1 - 0.0034 16.9 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 KKK46574.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 KKK46574.1 - 0.059 12.7 0.2 0.085 12.2 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 KKK46574.1 - 0.2 12.2 0.0 0.23 12.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family CAAP1 PF15335.6 KKK46575.1 - 0.018 15.6 4.0 0.15 12.6 1.7 2.6 2 1 1 3 3 3 0 Caspase activity and apoptosis inhibitor 1 PDZ_3 PF17815.1 KKK46575.1 - 0.02 14.8 0.2 3.4 7.5 0.0 2.2 1 1 1 2 2 2 0 PDZ domain PHP PF02811.19 KKK46576.1 - 5.9e-07 29.9 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 PHP domain DUF1148 PF06618.11 KKK46576.1 - 0.05 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) Latrotoxin_C PF15658.6 KKK46577.1 - 0.0091 15.8 0.6 0.019 14.7 0.2 1.9 1 1 1 2 2 2 1 Latrotoxin C-terminal domain LupA PF18242.1 KKK46577.1 - 0.06 13.0 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Inhibitor_I29 PF08246.12 KKK46577.1 - 8.2 7.0 10.9 6.5 7.3 1.3 2.3 1 1 1 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) PAS PF00989.25 KKK46579.1 - 9.7e-21 73.9 0.0 1.1e-15 57.6 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 KKK46579.1 - 1.2e-15 57.7 0.0 1.9e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KKK46579.1 - 1.9e-15 57.0 1.0 4.1e-11 43.1 0.1 3.3 2 1 0 2 2 2 2 PAS domain HATPase_c PF02518.26 KKK46579.1 - 1.5e-13 51.2 0.5 1.5e-13 51.2 0.5 2.9 2 2 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 KKK46579.1 - 4.7e-09 36.1 0.0 0.004 17.1 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 KKK46579.1 - 4.9e-07 29.9 0.0 7.6e-05 22.9 0.0 3.7 4 0 0 4 4 4 1 PAS fold HisKA PF00512.25 KKK46579.1 - 0.0003 20.7 0.4 0.00076 19.5 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 KKK46579.1 - 0.0014 18.8 0.1 0.14 12.4 0.0 3.0 3 1 0 3 3 3 1 PAS fold HATPase_c_5 PF14501.6 KKK46579.1 - 0.011 15.7 3.5 0.016 15.1 1.7 2.2 1 1 1 2 2 2 0 GHKL domain PAS_12 PF18095.1 KKK46579.1 - 0.016 14.9 0.3 0.052 13.2 0.0 2.1 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain PAS_10 PF13596.6 KKK46579.1 - 0.028 15.0 0.0 0.16 12.6 0.0 2.4 2 0 0 2 2 2 0 PAS domain HATPase_c_2 PF13581.6 KKK46579.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain H_kinase_N PF12282.8 KKK46579.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal transduction histidine kinase Response_reg PF00072.24 KKK46580.1 - 2e-19 69.8 0.2 2.2e-19 69.7 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain HTH_20 PF12840.7 KKK46582.1 - 4.2e-10 39.5 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 KKK46582.1 - 8.7e-10 38.3 0.2 1.8e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 KKK46582.1 - 7.3e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 KKK46582.1 - 1.9e-05 24.5 0.1 7e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 KKK46582.1 - 3e-05 23.5 0.1 7.1e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 KKK46582.1 - 0.0015 18.4 0.1 0.0076 16.1 0.1 2.2 2 0 0 2 2 2 1 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 KKK46582.1 - 0.002 18.1 0.9 0.0033 17.4 0.2 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain RepL PF05732.11 KKK46582.1 - 0.0026 17.2 0.2 0.0026 17.2 0.2 1.8 2 1 0 2 2 2 1 Firmicute plasmid replication protein (RepL) Sigma70_r4 PF04545.16 KKK46582.1 - 0.0062 16.0 0.1 0.015 14.8 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 KKK46582.1 - 0.01 15.6 0.2 0.033 14.0 0.1 2.0 2 0 0 2 2 2 0 HTH DNA binding domain MarR PF01047.22 KKK46582.1 - 0.013 15.5 0.1 0.036 14.0 0.1 1.8 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 KKK46582.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.11 KKK46582.1 - 0.07 13.2 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain KORA PF16509.5 KKK46582.1 - 0.095 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor YdaS_antitoxin PF15943.5 KKK46582.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Osmo_CC PF08946.10 KKK46582.1 - 3.7 7.9 7.1 21 5.5 0.3 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil AAA PF00004.29 KKK46583.1 - 5.4e-47 159.5 0.1 1.4e-46 158.2 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KKK46583.1 - 2.4e-12 46.4 0.0 4.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KKK46583.1 - 1.7e-06 28.5 0.0 0.00013 22.4 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KKK46583.1 - 1.8e-05 24.9 0.0 4.3e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KKK46583.1 - 3.5e-05 23.6 0.0 0.00022 21.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KKK46583.1 - 7.7e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KKK46583.1 - 9.3e-05 22.7 0.0 0.0011 19.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KKK46583.1 - 0.0001 22.3 0.2 0.00087 19.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KKK46583.1 - 0.00052 19.8 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KKK46583.1 - 0.0009 19.8 0.0 0.0025 18.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 KKK46583.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KKK46583.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KKK46583.1 - 0.002 18.3 0.0 0.0038 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KKK46583.1 - 0.0039 17.2 0.0 0.0082 16.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KKK46583.1 - 0.0048 16.1 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KKK46583.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KKK46583.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 KKK46583.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.22 KKK46583.1 - 0.032 14.6 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KKK46583.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 KKK46583.1 - 0.038 13.9 0.0 1.8 8.4 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KKK46583.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 KKK46583.1 - 0.049 13.2 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KKK46583.1 - 0.049 13.4 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KKK46583.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein PAS_2 PF08446.11 KKK46583.1 - 0.066 13.9 0.0 0.31 11.7 0.0 2.0 1 1 0 1 1 1 0 PAS fold Zeta_toxin PF06414.12 KKK46583.1 - 0.084 12.1 0.0 0.28 10.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin ApoLp-III PF07464.11 KKK46583.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Sigma54_activ_2 PF14532.6 KKK46583.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KKK46583.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KKK46583.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF900 PF05990.12 KKK46583.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) SecY PF00344.20 KKK46587.1 - 1.5e-60 205.1 17.5 2e-60 204.6 17.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KKK46587.1 - 1.2e-16 60.3 0.5 4.5e-16 58.4 0.5 2.1 1 0 0 1 1 1 1 Plug domain of Sec61p Phage_holin_5_2 PF16079.5 KKK46587.1 - 0.011 16.0 0.5 0.011 16.0 0.5 4.2 6 0 0 6 6 6 0 Phage holin family Hol44, in holin superfamily V DUF3368 PF11848.8 KKK46587.1 - 0.082 12.7 0.5 0.44 10.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) Ribosomal_60s PF00428.19 KKK46588.1 - 6.7e-10 39.4 13.6 9.6e-10 38.9 13.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Hydrolase PF00702.26 KKK46588.1 - 0.01 16.2 0.5 0.011 16.0 0.5 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2797 PF10977.8 KKK46588.1 - 0.069 13.0 0.3 0.081 12.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) RL10P_insert PF17777.1 KKK46589.1 - 2.2e-19 69.2 0.3 7.2e-19 67.6 0.1 1.9 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KKK46589.1 - 8.2e-17 61.2 1.4 1.6e-16 60.3 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 KKK46589.1 - 0.19 12.3 0.4 0.19 12.3 0.4 2.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ribosomal_L1 PF00687.21 KKK46590.1 - 1.1e-35 123.3 4.3 1.3e-35 123.0 4.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L11 PF00298.19 KKK46591.1 - 5.5e-17 62.0 0.2 7.5e-17 61.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KKK46591.1 - 0.00017 21.3 0.4 0.00032 20.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Lokiarchaeota/archeaon_Loki-ASM98684v1/GCA_000986845.1_ASM98684v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Lokiarchaeota/archeaon_Loki-ASM98684v1/GCA_000986845.1_ASM98684v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Lokiarchaeota/archeaon_Loki-ASM98684v1/GCA_000986845.1_ASM98684v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Archaea/Lokiarchaeota/archeaon_Loki-ASM98684v1/GCA_000986845.1_ASM98684v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 16:43:37 2019 # [ok]