# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Ribosomal_L4 PF00573.17 KEP59771.1 - 1.7e-10 40.6 0.3 2.8e-10 39.9 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L2_C PF03947.13 KEP59772.1 - 4.1e-28 97.7 0.0 5.3e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_S19 PF00203.16 KEP59773.1 - 2.1e-06 27.2 0.1 2.4e-06 27.0 0.1 1.2 1 1 0 1 1 1 1 Ribosomal protein S19 Ribosomal_S3_C PF00189.15 KEP59774.1 - 1.8e-15 56.8 5.4 1.8e-15 56.8 3.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain Ribosomal_L16 PF00252.13 KEP59775.1 - 1.1e-07 31.6 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3910 PF13049.1 KEP59776.1 - 0.061 13.4 0.7 0.079 13.0 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3910) Ribosomal_L14 PF00238.14 KEP59777.1 - 9.2e-27 93.2 0.4 9.9e-27 93.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Stn1_C PF12659.2 KEP59777.1 - 0.01 15.6 0.3 0.013 15.3 0.2 1.2 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH Ribosomal_L6 PF00347.18 KEP59778.1 - 9.9e-05 22.7 0.2 0.00016 22.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6 Ribosomal_S5 PF00333.15 KEP59779.1 - 1.4e-10 40.7 0.3 2.4e-10 39.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L36 PF00444.13 KEP59780.1 - 2.9e-09 36.7 11.1 3.1e-09 36.6 7.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 Baculo_ME53 PF06061.6 KEP59780.1 - 0.27 10.2 5.4 0.27 10.1 3.8 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 Ribosomal_S11 PF00411.14 KEP59781.1 - 6.8e-08 32.6 0.0 9.6e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S11 Ribosom_S12_S23 PF00164.20 KEP59782.1 - 3.7e-08 32.8 0.1 3.9e-08 32.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.16 KEP59783.1 - 3e-05 23.6 0.3 3.6e-05 23.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GTP_EFTU_D3 PF03143.12 KEP59784.1 - 3e-30 104.3 0.1 5.1e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEP59784.1 - 2.2e-06 27.6 1.1 7.6e-06 25.9 0.1 2.1 2 1 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KEP59784.1 - 0.16 11.6 1.3 0.45 10.1 0.1 2.2 2 1 1 3 3 3 0 Elongation factor Tu domain 4 DUF2986 PF11661.3 KEP59785.1 - 1.7 8.9 5.5 2 8.7 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) PRANC PF09372.5 KEP59786.1 - 1.9 8.5 11.1 2.1 8.3 7.7 1.1 1 0 0 1 1 1 0 PRANC domain AAA_2 PF07724.9 KEP59788.1 - 1.8e-48 164.7 0.0 1.9e-37 128.8 0.0 2.5 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KEP59788.1 - 1.3e-14 53.8 0.0 4e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KEP59788.1 - 8.4e-14 51.9 0.1 7.1e-09 35.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEP59788.1 - 1.1e-13 51.1 0.0 7.3e-11 41.9 0.0 3.1 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KEP59788.1 - 3.2e-06 26.7 0.0 9.3e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 KEP59788.1 - 3.1e-05 24.7 0.0 0.00014 22.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP59788.1 - 0.00021 21.3 0.0 0.029 14.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEP59788.1 - 0.00061 19.9 0.1 0.005 16.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEP59788.1 - 0.0049 15.9 0.0 0.057 12.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KEP59788.1 - 0.0049 15.9 0.0 0.012 14.7 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KEP59788.1 - 0.0095 16.2 5.3 0.022 15.0 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KEP59788.1 - 0.011 15.6 0.0 0.094 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KEP59788.1 - 0.014 15.4 0.1 0.13 12.2 0.0 2.7 2 2 0 2 2 2 0 Sigma-54 interaction domain DUF258 PF03193.11 KEP59788.1 - 0.044 12.9 0.1 7.9 5.6 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KEP59788.1 - 0.061 13.6 0.1 0.47 10.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.16 KEP59788.1 - 0.1 11.7 0.1 0.42 9.7 0.1 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ribosomal_S2 PF00318.15 KEP59791.1 - 2.4e-33 115.1 18.7 2.7e-33 114.9 12.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 RNA_pol_Rpb1_5 PF04998.12 KEP59793.1 - 5.7e-12 45.4 0.0 5.7e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KEP59794.1 - 4.2e-20 72.3 0.9 7.4e-20 71.4 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KEP59794.1 - 4.4e-07 30.0 0.0 9.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RAP-1 PF03085.10 KEP59794.1 - 0.011 15.0 5.8 0.021 14.2 4.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CENP-O PF09496.5 KEP59794.1 - 0.044 14.0 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component RNA_pol_Rpb2_3 PF04565.11 KEP59795.1 - 5e-20 71.0 2.9 1.4e-19 69.5 0.1 2.7 2 1 1 3 3 3 1 RNA polymerase Rpb2, domain 3 UPF0051 PF01458.12 KEP59796.1 - 2.8e-39 134.9 0.0 5.8e-39 133.8 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein family (UPF0051) zf-CCCH PF00642.19 KEP59797.1 - 1.3e-07 31.0 24.7 2.6e-06 26.9 1.8 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_4 PF13418.1 KEP59798.1 - 1.9e-38 130.0 11.1 7.8e-10 38.3 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP59798.1 - 4e-35 119.1 11.2 1.4e-07 31.4 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KEP59798.1 - 2.9e-25 87.7 0.7 0.00032 20.5 0.0 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KEP59798.1 - 1.2e-23 82.3 14.0 0.00057 19.3 0.5 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KEP59798.1 - 1.7e-22 78.5 16.4 0.00029 20.8 0.0 6.7 5 2 2 7 7 6 6 Kelch motif Kelch_2 PF07646.10 KEP59798.1 - 2.5e-11 42.8 13.7 0.0027 17.3 0.1 6.9 6 1 0 6 6 6 4 Kelch motif TMF_DNA_bd PF12329.3 KEP59798.1 - 4.6e-05 23.1 0.9 4.6e-05 23.1 0.6 3.0 3 1 0 3 3 2 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KEP59798.1 - 8e-05 21.9 2.3 0.00012 21.3 1.6 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Laminin_II PF06009.7 KEP59798.1 - 0.00084 19.1 5.9 0.0018 18.0 4.1 1.6 1 0 0 1 1 1 1 Laminin Domain II Nup54 PF13874.1 KEP59798.1 - 0.001 18.7 0.2 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 EzrA PF06160.7 KEP59798.1 - 0.0015 16.8 3.4 0.0021 16.3 2.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA SseC PF04888.7 KEP59798.1 - 0.0017 17.7 1.0 0.0017 17.7 0.7 2.1 2 0 0 2 2 1 1 Secretion system effector C (SseC) like family GAS PF13851.1 KEP59798.1 - 0.0035 16.5 0.7 0.0035 16.5 0.5 2.4 2 1 0 2 2 1 1 Growth-arrest specific micro-tubule binding MCPsignal PF00015.16 KEP59798.1 - 0.0079 15.7 5.6 0.0079 15.7 3.9 1.6 2 0 0 2 2 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain COG6 PF06419.6 KEP59798.1 - 0.0094 14.1 4.9 0.015 13.4 3.4 1.3 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Syntaxin_2 PF14523.1 KEP59798.1 - 0.011 15.6 0.8 0.11 12.5 0.1 2.4 1 1 1 2 2 2 0 Syntaxin-like protein Baculo_PEP_C PF04513.7 KEP59798.1 - 0.037 13.8 0.4 0.21 11.4 0.2 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KEP59798.1 - 0.043 14.0 3.6 0.68 10.2 0.7 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 KEP59798.1 - 0.13 12.4 3.2 0.33 11.1 2.2 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 KEP59798.1 - 0.24 11.2 3.0 0.63 9.9 0.8 2.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 KEP59798.1 - 0.28 10.9 7.1 0.071 12.9 2.5 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) COG2 PF06148.6 KEP59798.1 - 0.96 9.3 8.1 1.5e+02 2.2 5.6 2.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.1 KEP59798.1 - 3.3 6.0 18.5 0.017 13.5 1.4 2.2 2 0 0 2 2 2 0 AAA domain Suf PF05843.9 KEP59798.1 - 5.8 6.5 9.0 1.3 8.7 2.8 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pkinase PF00069.20 KEP59800.1 - 4.7e-44 150.4 0.0 3.4e-41 141.1 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP59800.1 - 1.4e-14 53.7 0.0 5.8e-12 45.2 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KEP59800.1 - 0.0022 17.7 0.0 0.0068 16.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family SPC25 PF06703.6 KEP59801.1 - 2.2e-11 43.5 0.2 3.6e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pex24p PF06398.6 KEP59801.1 - 0.089 11.5 0.1 0.28 9.9 0.0 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin MaoC_dehydratas PF01575.14 KEP59802.1 - 4e-25 87.5 0.0 6.4e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KEP59802.1 - 3e-08 33.5 0.0 9.8e-06 25.3 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase MFS_1 PF07690.11 KEP59803.1 - 2.1e-21 76.0 45.9 3.4e-11 42.4 14.6 2.9 1 1 0 2 2 2 2 Major Facilitator Superfamily zf-DHHC PF01529.15 KEP59804.1 - 1e-16 60.8 13.2 2.5e-16 59.5 9.1 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF4131 PF13567.1 KEP59804.1 - 0.0053 16.1 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Claudin_2 PF13903.1 KEP59804.1 - 1.6 8.4 5.1 3.1 7.4 1.3 2.4 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Form_Nir_trans PF01226.12 KEP59805.1 - 9.3e-77 257.3 13.9 1.1e-76 257.0 9.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter TrbC PF04956.8 KEP59805.1 - 1.1 9.3 6.2 0.23 11.5 1.3 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family HEAT PF02985.17 KEP59806.1 - 2.4e-14 52.0 11.2 0.067 13.2 0.0 10.3 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 KEP59806.1 - 1.2e-13 51.0 21.6 2.1e-06 27.9 0.0 8.9 6 4 5 11 11 11 5 HEAT repeats HEAT_EZ PF13513.1 KEP59806.1 - 1.8e-09 37.8 21.8 6.9e-05 23.2 0.0 9.9 10 1 1 11 11 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KEP59806.1 - 7.8e-09 35.8 7.7 0.25 11.7 0.0 7.9 7 2 3 10 10 9 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 KEP59806.1 - 4.3e-08 32.6 1.2 0.98 9.3 0.0 7.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 KEP59806.1 - 0.0003 20.6 0.8 0.004 17.0 0.1 3.6 2 1 0 2 2 1 1 Importin-beta N-terminal domain DUF2454 PF10521.4 KEP59806.1 - 0.002 17.1 0.1 0.057 12.4 0.0 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF2454) CTD_bind PF04818.8 KEP59806.1 - 0.0028 17.8 0.0 3 8.1 0.0 4.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. HEAT_PBS PF03130.11 KEP59806.1 - 0.015 15.7 4.9 3.1 8.5 0.0 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF3385 PF11865.3 KEP59806.1 - 0.023 14.5 1.4 7.2 6.5 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) AAA_25 PF13481.1 KEP59806.1 - 0.13 11.5 2.4 0.36 10.1 0.0 3.0 3 1 1 4 4 4 0 AAA domain Cyclin_C PF02984.14 KEP59807.1 - 1.7e-07 31.1 0.1 7.2e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF4175 PF13779.1 KEP59807.1 - 0.0042 14.8 0.0 0.0065 14.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Presenilin PF01080.12 KEP59807.1 - 2.7 6.6 4.2 0.62 8.8 0.4 1.7 1 1 1 2 2 2 0 Presenilin LRR_9 PF14580.1 KEP59808.1 - 6.9e-56 188.5 0.0 8.8e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KEP59808.1 - 1.9e-12 46.4 26.1 2.7e-07 30.0 4.1 4.3 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP59808.1 - 2.2e-11 43.3 10.7 4.2e-10 39.2 1.3 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KEP59808.1 - 8.5e-07 28.4 0.8 0.024 14.6 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.28 KEP59808.1 - 0.00028 20.5 11.2 0.2 11.7 0.1 5.6 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 KEP59808.1 - 0.00053 19.7 5.1 3.6 8.2 0.0 5.2 5 0 0 5 5 5 1 Leucine rich repeat Ribosomal_L28e PF01778.12 KEP59812.1 - 3.3e-27 95.2 3.9 3.7e-27 95.0 2.7 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF3232 PF11554.3 KEP59813.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) ADP_PFK_GK PF04587.10 KEP59813.1 - 9.2 4.3 0.4 14 3.7 0.2 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Kelch_4 PF13418.1 KEP59816.1 - 1.8e-35 120.4 4.5 5.2e-10 38.9 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP59816.1 - 5.8e-32 109.1 2.3 1.2e-05 25.3 0.0 7.7 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.1 KEP59816.1 - 1.4e-29 100.9 3.0 2.7e-07 30.4 0.2 6.4 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KEP59816.1 - 1e-24 85.9 0.8 0.0061 16.4 0.0 6.6 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.1 KEP59816.1 - 4.3e-22 77.7 2.0 4.3e-22 77.7 1.4 4.1 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.10 KEP59816.1 - 9.8e-19 66.3 3.8 5.6e-05 22.7 0.0 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KEP59816.1 - 1.2e-16 59.9 3.3 0.00022 20.7 0.0 5.4 5 1 0 5 5 5 3 Kelch motif Hydrolase_3 PF08282.7 KEP59818.1 - 1.1e-48 166.0 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEP59818.1 - 3.4e-12 46.2 0.0 6.8e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 KEP59818.1 - 0.00074 19.9 0.3 0.0051 17.2 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP59818.1 - 0.014 15.5 0.0 0.074 13.2 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ldh_1_N PF00056.18 KEP59818.1 - 0.046 13.5 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Hydrolase_3 PF08282.7 KEP59819.1 - 2.2e-47 161.7 0.0 2.7e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEP59819.1 - 8.9e-13 48.0 0.0 1.5e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase RAP PF08373.5 KEP59820.1 - 0.00039 20.1 0.1 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 RAP domain HEAT_2 PF13646.1 KEP59821.1 - 1.3e-10 41.3 27.0 0.007 16.6 2.4 6.9 4 3 2 6 6 6 3 HEAT repeats HEAT PF02985.17 KEP59821.1 - 8.9e-10 37.8 28.2 0.021 14.8 0.0 9.5 10 0 0 10 10 10 4 HEAT repeat Adaptin_N PF01602.15 KEP59821.1 - 1.3e-06 27.1 0.2 1 7.5 0.0 4.7 4 1 0 4 4 4 3 Adaptin N terminal region OTCace_N PF02729.16 KEP59821.1 - 0.022 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain FdhE PF04216.7 KEP59821.1 - 0.085 12.5 8.7 0.21 11.2 0.3 2.9 2 1 1 3 3 3 0 Protein involved in formate dehydrogenase formation Arm PF00514.18 KEP59821.1 - 0.26 11.1 6.6 12 5.9 0.1 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Transaldolase PF00923.14 KEP59822.1 - 4.8e-100 334.3 0.3 5.8e-100 334.1 0.2 1.1 1 0 0 1 1 1 1 Transaldolase RbcS PF12338.3 KEP59822.1 - 0.092 12.5 1.2 0.24 11.1 0.8 1.7 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit LRAT PF04970.8 KEP59824.1 - 1.2e-21 76.9 0.0 3e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF87 PF01935.12 KEP59824.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF3633 PF12315.3 KEP59825.1 - 7.9e-09 35.1 0.1 2.2e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3633) LIM PF00412.17 KEP59825.1 - 0.0028 17.6 0.2 0.0028 17.6 0.1 5.9 6 1 1 7 7 7 3 LIM domain Med27 PF11571.3 KEP59825.1 - 0.0097 16.0 9.8 0.32 11.1 0.2 4.4 5 0 0 5 5 5 2 Mediator complex subunit 27 CtnDOT_TraJ PF07863.6 KEP59825.1 - 3 8.3 8.0 18 5.9 0.1 3.5 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon PDEase_I PF00233.14 KEP59826.1 - 9.8e-43 146.5 0.3 1.4e-42 146.0 0.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Cytochrom_C PF00034.16 KEP59827.1 - 4.6e-08 33.7 0.0 1.2e-07 32.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KEP59827.1 - 0.0001 22.3 0.5 0.00035 20.6 0.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KEP59827.1 - 0.0013 18.2 0.0 0.05 13.0 0.0 2.3 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 KEP59827.1 - 0.047 13.3 0.1 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C1 family zf-RING_2 PF13639.1 KEP59828.1 - 9.6e-12 44.5 5.6 2.1e-11 43.4 3.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEP59828.1 - 1e-06 28.3 4.0 1.9e-06 27.4 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KEP59828.1 - 2.4e-06 27.5 5.1 8.4e-06 25.8 3.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEP59828.1 - 2.7e-06 27.3 5.5 6.2e-06 26.1 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP59828.1 - 2.4e-05 23.8 3.8 4.9e-05 22.8 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP59828.1 - 3.9e-05 23.2 2.7 9.2e-05 22.0 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEP59828.1 - 0.00053 19.7 1.2 0.0011 18.7 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KEP59828.1 - 0.0067 16.4 4.9 0.014 15.4 3.4 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 KEP59828.1 - 0.039 13.6 1.3 0.071 12.8 0.5 1.8 1 1 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 KEP59828.1 - 0.13 11.9 1.9 0.3 10.8 1.3 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KEP59828.1 - 0.18 11.4 2.9 0.33 10.5 2.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KEP59828.1 - 0.26 11.3 4.1 0.54 10.2 2.8 1.6 1 0 0 1 1 1 0 RING-like domain RBM39linker PF15519.1 KEP59829.1 - 0.052 13.8 0.3 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein SNF2_N PF00176.18 KEP59830.1 - 5.8e-51 173.0 0.2 5.5e-43 146.8 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP59830.1 - 3.5e-11 42.8 0.0 1.1e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP59830.1 - 3.2e-06 26.7 0.0 7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEP59830.1 - 1.7e-05 24.7 0.0 5.4e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KEP59830.1 - 0.027 13.3 0.0 0.29 9.8 0.0 2.4 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Btz PF09405.5 KEP59831.1 - 1.3e-08 34.9 2.1 1.3e-08 34.9 1.4 3.2 3 1 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding EF-hand_7 PF13499.1 KEP59832.1 - 1.1e-28 99.1 14.6 1.3e-10 41.2 0.7 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KEP59832.1 - 7e-23 78.1 17.9 7.8e-05 21.6 0.2 6.0 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.1 KEP59832.1 - 1.2e-21 74.5 12.7 4.6e-05 22.9 0.0 6.5 5 1 1 6 6 6 5 EF-hand domain EF-hand_5 PF13202.1 KEP59832.1 - 6.3e-20 69.5 16.9 1e-05 24.6 0.0 6.0 6 0 0 6 6 6 4 EF hand SPARC_Ca_bdg PF10591.4 KEP59832.1 - 8.2e-11 41.9 11.2 0.00049 20.0 0.1 3.5 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 KEP59832.1 - 3.7e-10 39.2 15.8 0.0016 18.0 0.1 5.6 1 1 5 6 6 6 5 EF-hand domain pair Unstab_antitox PF09720.5 KEP59832.1 - 0.0068 16.0 4.0 0.097 12.3 0.1 3.2 3 0 0 3 3 3 1 Putative addiction module component DUF4174 PF13778.1 KEP59832.1 - 0.059 13.4 3.5 8.8 6.4 1.1 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4174) Beta_elim_lyase PF01212.16 KEP59832.1 - 0.071 12.2 0.6 0.8 8.7 0.0 2.7 1 1 3 4 4 4 0 Beta-eliminating lyase TRCF PF03461.10 KEP59832.1 - 0.093 12.7 1.9 0.14 12.1 0.1 2.2 3 0 0 3 3 3 0 TRCF domain EF-hand_10 PF14788.1 KEP59832.1 - 0.12 12.0 6.1 14 5.3 0.0 4.5 4 1 0 4 4 4 0 EF hand BDV_P24 PF06595.6 KEP59832.1 - 0.34 10.6 7.6 1.6 8.4 0.1 2.4 1 1 0 2 2 2 0 Borna disease virus P24 protein EF-hand_4 PF12763.2 KEP59832.1 - 0.89 9.3 13.5 17 5.2 0.2 4.3 2 1 2 5 5 5 0 Cytoskeletal-regulatory complex EF hand TPR_11 PF13414.1 KEP59833.1 - 1.3e-16 60.0 5.3 3.5e-11 42.5 1.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEP59833.1 - 5.9e-12 44.6 8.1 7.9e-06 25.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP59833.1 - 1.3e-09 37.2 8.2 0.00013 21.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEP59833.1 - 3.1e-05 23.7 1.5 0.00011 22.0 1.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP59833.1 - 0.00014 21.3 2.0 0.019 14.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP59833.1 - 0.00054 19.9 0.2 0.0043 17.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP59833.1 - 0.008 16.7 2.8 0.075 13.7 0.1 3.5 2 1 1 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEP59833.1 - 0.026 14.6 4.0 0.11 12.5 0.5 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEP59833.1 - 0.039 14.4 0.8 0.34 11.4 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEP59833.1 - 0.047 14.3 8.8 0.053 14.2 0.2 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEP59833.1 - 0.058 13.7 3.3 0.1 12.9 1.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Endomucin PF07010.7 KEP59833.1 - 0.059 12.6 0.9 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Endomucin UBA_2 PF08587.6 KEP59833.1 - 0.14 12.3 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) TPR_12 PF13424.1 KEP59833.1 - 0.78 9.7 8.5 0.99 9.3 1.6 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 KEP59836.1 - 1e-28 100.2 0.0 1.8e-15 56.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP59836.1 - 2.5e-13 49.6 0.0 3.1e-09 36.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 KEP59836.1 - 0.034 13.1 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEP59836.1 - 1.3 7.8 0.0 5.4 5.8 0.0 1.8 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.4 KEP59836.1 - 3.8 6.8 0.0 6.8 5.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KEP59836.1 - 4.4 6.6 0.0 8.4 5.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 KEP59836.1 - 5.2 6.5 0.0 8.8 5.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Josephin PF02099.12 KEP59838.1 - 6.5e-45 152.5 0.0 1.1e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Josephin UBX PF00789.15 KEP59838.1 - 3.1e-08 33.5 0.0 5.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Peptidase_C12 PF01088.16 KEP59838.1 - 0.057 12.6 0.0 0.15 11.2 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Ribosom_S12_S23 PF00164.20 KEP59839.1 - 2.6e-41 139.8 0.7 3e-41 139.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ThiF PF00899.16 KEP59841.1 - 3.6e-19 68.9 0.0 6.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KEP59841.1 - 0.026 14.6 0.0 0.089 12.8 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.10 KEP59841.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain MIP-T3 PF10243.4 KEP59841.1 - 0.44 8.9 25.7 1.4 7.3 17.8 1.8 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAPS PF04499.10 KEP59841.1 - 1.9 7.0 4.2 3.5 6.1 2.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein OTU PF02338.14 KEP59842.1 - 6.2e-15 55.8 1.2 1.2e-14 54.9 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KEP59842.1 - 0.0019 17.5 0.0 0.88 8.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain RRM_6 PF14259.1 KEP59844.1 - 0.0069 16.3 0.0 1.1 9.2 0.0 3.6 4 0 0 4 4 4 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FimP PF09766.4 KEP59845.1 - 2.1e-07 30.3 0.0 3.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Fms-interacting protein GlcNAc_2-epim PF07221.6 KEP59845.1 - 0.082 11.9 0.3 0.15 11.0 0.2 1.3 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) GalKase_gal_bdg PF10509.4 KEP59847.1 - 3.7e-19 67.7 0.0 7.2e-19 66.8 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 KEP59847.1 - 4e-12 46.0 2.2 4e-12 46.0 1.5 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEP59847.1 - 3e-08 33.7 0.1 1.2e-07 31.8 0.1 2.1 1 0 0 1 1 1 1 GHMP kinases C terminal GLTSCR1 PF15249.1 KEP59848.1 - 0.045 13.8 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region CDC27 PF09507.5 KEP59848.1 - 0.11 11.7 8.0 0.25 10.5 5.6 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macro PF01661.16 KEP59850.1 - 0.0003 20.6 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain EF-hand_1 PF00036.27 KEP59851.1 - 1.6e-15 55.1 2.2 3e-05 23.0 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KEP59851.1 - 2e-11 42.7 3.4 0.014 15.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KEP59851.1 - 5.7e-11 42.3 3.5 2.2e-05 24.4 0.1 2.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEP59851.1 - 9.2e-08 31.1 0.6 0.00031 19.9 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KEP59851.1 - 5.9e-07 28.9 2.6 0.00089 18.8 0.2 3.8 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 KEP59851.1 - 1.2e-05 25.0 0.2 0.036 13.9 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KEP59851.1 - 0.013 15.5 0.0 0.11 12.5 0.0 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.7 KEP59854.1 - 3.2e-38 131.3 1.1 5.7e-38 130.5 0.7 1.4 1 1 0 1 1 1 1 p25-alpha SurA_N PF09312.6 KEP59854.1 - 0.0071 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 SurA N-terminal domain WSS_VP PF12175.3 KEP59854.1 - 0.058 12.4 0.1 0.075 12.1 0.1 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP pRN1_helical PF13010.1 KEP59854.1 - 0.071 12.7 0.3 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Primase helical domain SYF2 PF08231.7 KEP59855.1 - 9.5e-38 129.7 7.9 9.5e-38 129.7 5.5 2.8 2 1 0 2 2 2 1 SYF2 splicing factor Pro_isomerase PF00160.16 KEP59855.1 - 1.4e-36 126.0 0.0 3.5e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA PF00004.24 KEP59856.1 - 5.1e-45 152.8 0.2 9.8e-44 148.7 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KEP59856.1 - 3.8e-08 33.4 0.0 8.7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEP59856.1 - 6.2e-08 32.4 0.2 2.1e-07 30.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEP59856.1 - 9.1e-07 29.0 1.4 0.00024 21.2 0.3 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEP59856.1 - 2.5e-05 24.3 0.0 0.00011 22.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KEP59856.1 - 3.1e-05 23.0 0.0 8.7e-05 21.5 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 KEP59856.1 - 7e-05 21.9 0.0 0.00017 20.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KEP59856.1 - 0.00018 21.5 0.0 0.00057 19.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEP59856.1 - 0.00022 22.0 0.1 0.0014 19.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KEP59856.1 - 0.00069 19.3 0.1 0.019 14.6 0.0 2.6 3 0 0 3 3 3 1 NTPase AAA_25 PF13481.1 KEP59856.1 - 0.00071 19.0 2.4 0.035 13.5 0.1 3.1 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KEP59856.1 - 0.00083 18.8 0.0 0.0022 17.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KEP59856.1 - 0.00097 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 KEP59856.1 - 0.0011 18.8 0.1 0.0028 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEP59856.1 - 0.0015 17.7 0.1 0.0034 16.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEP59856.1 - 0.0015 18.1 0.1 0.039 13.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEP59856.1 - 0.0018 18.5 0.0 0.019 15.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KEP59856.1 - 0.0027 16.4 0.0 0.0075 15.0 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 KEP59856.1 - 0.0027 17.6 0.0 0.0077 16.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KEP59856.1 - 0.0029 17.1 0.1 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KEP59856.1 - 0.003 17.2 0.4 0.071 12.7 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 KEP59856.1 - 0.0032 17.0 0.2 0.007 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP59856.1 - 0.0045 16.7 0.8 0.013 15.2 0.6 1.7 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KEP59856.1 - 0.0055 16.3 0.3 0.077 12.6 0.1 2.4 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 KEP59856.1 - 0.0057 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin UPF0079 PF02367.12 KEP59856.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 KEP59856.1 - 0.012 15.0 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KEP59856.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KEP59856.1 - 0.02 14.9 0.0 0.073 13.1 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 KEP59856.1 - 0.032 14.5 0.1 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KEP59856.1 - 0.04 12.7 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 KEP59856.1 - 0.052 12.6 1.5 0.61 9.1 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.1 KEP59856.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEP59856.1 - 0.083 12.1 0.1 0.19 10.9 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein SKI PF01202.17 KEP59856.1 - 0.085 12.7 1.2 9.8 6.0 0.0 3.0 3 1 0 3 3 3 0 Shikimate kinase ABC_tran PF00005.22 KEP59856.1 - 0.11 12.8 0.5 0.39 11.0 0.0 2.4 2 2 0 2 2 2 0 ABC transporter Torsin PF06309.6 KEP59856.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin Cpn60_TCP1 PF00118.19 KEP59857.1 - 4.4e-142 474.1 8.3 5e-142 473.9 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rav1p_C PF12234.3 KEP59858.1 - 2.7e-25 88.6 0.6 7.6e-21 73.9 0.9 3.3 4 0 0 4 4 4 2 RAVE protein 1 C terminal DUF979 PF06166.7 KEP59858.1 - 5.7 5.8 0.0 9.6 5.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) DUF3272 PF11676.3 KEP59858.1 - 8.3 6.5 0.1 17 5.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) Suf PF05843.9 KEP59859.1 - 1.8e-20 73.8 0.0 8e-14 52.0 0.0 4.3 4 0 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KEP59859.1 - 1.2e-06 28.7 6.9 0.15 12.3 0.2 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEP59859.1 - 2.1e-06 28.2 31.3 0.0043 17.6 2.4 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEP59859.1 - 4e-06 26.9 24.0 0.0044 17.5 0.1 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEP59859.1 - 0.074 13.2 0.5 1.2 9.5 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP59859.1 - 0.3 11.1 7.9 2.2 8.4 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat HAT PF02184.11 KEP59859.1 - 2.9 7.7 4.2 43 3.9 0.0 3.2 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat Kinesin PF00225.18 KEP59860.1 - 7e-96 320.8 0.0 1.2e-95 320.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DALR_1 PF05746.10 KEP59860.1 - 0.012 15.5 0.1 0.039 13.9 0.1 1.9 1 0 0 1 1 1 0 DALR anticodon binding domain AAA_22 PF13401.1 KEP59860.1 - 0.025 14.7 0.1 0.2 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain BBP1_C PF15272.1 KEP59860.1 - 0.055 13.0 6.7 0.071 12.6 0.0 3.1 3 1 0 3 3 3 0 Spindle pole body component BBP1, C-terminal AAA_23 PF13476.1 KEP59860.1 - 8 6.7 9.9 24 5.1 0.1 3.2 3 1 0 3 3 3 0 AAA domain Seryl_tRNA_N PF02403.17 KEP59860.1 - 9.6 6.2 12.4 52 3.9 0.2 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.27 KEP59861.1 - 6.7e-08 32.1 14.1 0.00021 21.0 1.2 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat TrfA PF07042.6 KEP59861.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 TrfA protein Ribosomal_L3 PF00297.17 KEP59862.1 - 3.2e-23 82.4 0.4 5.2e-22 78.5 0.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Acetyltransf_1 PF00583.19 KEP59863.1 - 1.6e-08 34.4 0.1 4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEP59863.1 - 0.016 15.3 1.0 0.034 14.2 0.1 2.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain BolA PF01722.13 KEP59864.1 - 4.5e-22 77.7 0.0 5.5e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein DEAD PF00270.24 KEP59865.1 - 1.3e-12 47.5 0.0 5.9e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP59865.1 - 5.6e-08 32.5 0.1 1.4e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF106 PF01956.11 KEP59866.1 - 9.2e-31 106.6 0.3 9.2e-31 106.6 0.2 1.7 2 0 0 2 2 2 1 Integral membrane protein DUF106 UCR_14kD PF02271.11 KEP59869.1 - 0.021 14.5 4.8 0.95 9.2 0.9 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit FUSC PF04632.7 KEP59869.1 - 0.47 8.8 4.6 0.55 8.6 3.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CbiC PF02570.10 KEP59869.1 - 0.8 9.0 4.8 4 6.8 0.2 2.1 2 0 0 2 2 2 0 Precorrin-8X methylmutase KAP PF05804.7 KEP59871.1 - 5.8e-17 60.8 0.1 6.6e-17 60.7 0.1 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) VPS9 PF02204.13 KEP59872.1 - 3e-25 88.2 0.0 5.7e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ChAPs PF09295.5 KEP59873.1 - 4.1e-25 88.3 0.0 2.1e-13 49.8 0.0 3.3 3 0 0 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) RRM_1 PF00076.17 KEP59874.1 - 0.0033 17.0 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_32 PF13654.1 KEP59875.1 - 0.32 9.6 1.4 0.48 9.0 1.0 1.1 1 0 0 1 1 1 0 AAA domain DUF3508 PF12018.3 KEP59878.1 - 8.7e-19 67.5 0.0 1.6e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) IMCp PF12314.3 KEP59879.1 - 2e-08 34.2 19.7 2e-08 34.2 13.6 3.6 1 1 2 3 3 3 3 Inner membrane complex protein VPS11_C PF12451.3 KEP59880.1 - 4.7e-11 42.3 0.0 4.7e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal SEO_C PF14577.1 KEP59880.1 - 0.00061 19.2 2.4 0.00094 18.6 0.9 1.8 1 1 1 2 2 2 1 Sieve element occlusion C-terminus zf-RING_2 PF13639.1 KEP59880.1 - 0.34 10.7 5.3 1.1 9.1 3.7 2.0 1 0 0 1 1 1 0 Ring finger domain BRF1 PF07741.8 KEP59880.1 - 5.4 7.3 14.8 9.5 6.5 0.2 2.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Fip1 PF05182.8 KEP59881.1 - 4.7e-09 35.3 2.0 8.5e-09 34.5 1.4 1.4 1 0 0 1 1 1 1 Fip1 motif Reo_sigmaC PF04582.7 KEP59882.1 - 8 5.5 14.5 0.79 8.8 3.4 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein EF-hand_8 PF13833.1 KEP59883.1 - 3.4e-06 26.5 0.3 1.9e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 KEP59883.1 - 0.02 15.0 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_9 PF14658.1 KEP59883.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 KEP59883.1 - 0.074 12.3 0.1 0.3 10.5 0.1 2.0 2 0 0 2 2 2 0 EF hand SecE PF00584.15 KEP59884.1 - 9.5e-13 47.5 0.1 1.1e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex AhpC-TSA PF00578.16 KEP59886.1 - 4.7e-32 110.2 0.0 5.9e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEP59886.1 - 4.8e-13 48.8 0.0 7.2e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KEP59886.1 - 3.9e-08 32.8 0.0 7.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin E1-E2_ATPase PF00122.15 KEP59887.1 - 2.1e-67 226.5 4.5 2.5e-66 223.0 1.9 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEP59887.1 - 1.1e-47 161.9 0.9 1.1e-47 161.9 0.6 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEP59887.1 - 1e-32 114.3 0.0 1.3e-31 110.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP59887.1 - 7.1e-23 80.3 0.0 1.3e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KEP59887.1 - 1.1e-19 69.6 0.3 4.4e-19 67.6 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEP59887.1 - 4.9e-16 59.4 0.2 1.8e-15 57.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEP59887.1 - 7.8e-06 25.6 0.8 3.9e-05 23.3 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase G8 PF10162.4 KEP59887.1 - 0.14 11.9 0.1 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 G8 domain Synaptobrevin PF00957.16 KEP59888.1 - 2.8e-25 87.7 0.4 4e-25 87.2 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEP59888.1 - 1.5e-19 69.3 0.1 4.1e-19 67.9 0.0 1.7 1 1 1 2 2 2 1 Regulated-SNARE-like domain DUF3675 PF12428.3 KEP59888.1 - 0.025 14.8 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Herpes_teg_N PF04843.7 KEP59888.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region zinc_ribbon_6 PF14599.1 KEP59889.1 - 4.3e-24 84.0 0.0 4.3e-24 84.0 0.0 2.0 2 1 0 2 2 1 1 Zinc-ribbon zf-RING_2 PF13639.1 KEP59889.1 - 3.2e-06 26.8 15.4 3.2e-06 26.8 10.7 2.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEP59889.1 - 7.2e-05 22.7 14.4 7.2e-05 22.7 10.0 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEP59889.1 - 0.00011 21.8 7.9 0.00026 20.6 5.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KEP59889.1 - 0.00014 21.5 13.4 0.00014 21.5 9.3 2.7 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEP59889.1 - 0.00033 20.2 11.4 0.00033 20.2 7.9 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP59889.1 - 0.0004 20.0 13.2 0.0004 20.0 9.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 KEP59889.1 - 0.005 16.5 0.3 0.005 16.5 0.2 2.4 2 1 0 2 2 1 1 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 KEP59889.1 - 0.045 13.3 14.0 0.18 11.4 0.8 2.5 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Ribosomal_L37e PF01907.14 KEP59889.1 - 0.057 13.2 1.0 0.057 13.2 0.7 2.0 2 0 0 2 2 2 0 Ribosomal protein L37e zf-C3HC4_4 PF15227.1 KEP59889.1 - 0.073 12.9 17.0 0.042 13.7 7.0 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 KEP59889.1 - 0.078 12.1 3.1 0.088 12.0 2.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger C1_1 PF00130.17 KEP59889.1 - 0.66 9.7 20.2 0.91 9.3 0.2 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.1 KEP59889.1 - 3.7 7.2 18.7 0.048 13.2 6.4 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain ABC_ATPase PF09818.4 KEP59890.1 - 7.9e-184 611.4 0.0 9.5e-184 611.1 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 KEP59890.1 - 0.0002 21.7 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEP59890.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KEP59890.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 KEP59891.1 - 7e-20 70.4 37.0 0.0001 21.8 0.1 9.6 8 3 3 11 11 11 6 TPR repeat TPR_19 PF14559.1 KEP59891.1 - 1.3e-09 38.2 48.5 8.5e-05 22.8 0.3 10.9 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEP59891.1 - 7.1e-08 32.9 65.6 0.013 16.1 4.3 10.4 9 2 1 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 KEP59891.1 - 9.8e-08 31.2 1.5 0.018 14.6 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP59891.1 - 2.1e-07 30.5 13.2 13 6.2 0.0 10.1 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEP59891.1 - 3.7e-06 27.0 59.7 0.052 14.1 0.6 11.4 10 1 2 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.12 KEP59891.1 - 0.0014 18.3 0.1 0.0014 18.3 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP59891.1 - 0.0076 15.9 2.0 5.7 6.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEP59891.1 - 0.58 10.7 0.0 0.58 10.7 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat Ribosomal_L10 PF00466.15 KEP59893.1 - 1.6e-08 34.3 0.0 2.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Thr_dehydrat_C PF00585.13 KEP59893.1 - 0.08 12.5 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 C-terminal regulatory domain of Threonine dehydratase Moulting_cycle PF04870.11 KEP59893.1 - 0.15 11.1 0.1 7 5.6 0.0 2.0 2 0 0 2 2 2 0 Moulting cycle zf-CCCH PF00642.19 KEP59894.1 - 2.6e-08 33.3 24.5 6.3e-06 25.7 2.9 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GTP_EFTU PF00009.22 KEP59896.1 - 0.0032 16.9 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KEP59897.1 - 0.0072 16.6 0.5 0.02 15.1 0.0 2.0 2 1 0 2 2 2 1 ABC transporter Miro PF08477.8 KEP59897.1 - 0.024 15.1 0.1 0.082 13.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 KEP59897.1 - 0.043 13.7 0.1 0.043 13.7 0.1 2.6 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KEP59897.1 - 0.052 13.3 2.0 0.066 13.0 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KEP59897.1 - 0.64 10.8 0.1 0.64 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KEP59897.1 - 0.65 9.7 2.4 3.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family UNC-50 PF05216.8 KEP59898.1 - 1.3e-34 119.4 8.9 1.9e-34 118.8 6.2 1.2 1 0 0 1 1 1 1 UNC-50 family IncA PF04156.9 KEP59898.1 - 0.033 13.7 0.3 0.033 13.7 0.2 2.1 2 1 1 3 3 3 0 IncA protein DUF983 PF06170.7 KEP59898.1 - 4 7.6 8.9 0.28 11.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) FixP_N PF14715.1 KEP59898.1 - 6.7 6.1 7.1 7 6.1 0.4 2.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP AMA-1 PF02430.10 KEP59899.1 - 2.8e-60 204.5 1.0 6.7e-53 180.2 0.1 2.2 2 0 0 2 2 2 2 Apical membrane antigen 1 DUF4366 PF14283.1 KEP59899.1 - 0.00021 20.8 0.0 0.00078 18.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) CD34_antigen PF06365.7 KEP59899.1 - 0.00062 19.4 0.0 0.027 14.1 0.0 2.5 2 0 0 2 2 2 1 CD34/Podocalyxin family Nol1_Nop2_Fmu PF01189.12 KEP59900.1 - 1.8e-26 93.1 0.0 3.5e-17 62.7 0.0 3.8 4 0 0 4 4 4 2 NOL1/NOP2/sun family FtsJ PF01728.14 KEP59900.1 - 0.0075 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Tom22 PF04281.8 KEP59901.1 - 0.00026 20.5 0.1 0.0003 20.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CD20 PF04103.10 KEP59901.1 - 0.032 14.1 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 CD20-like family Cnd1 PF12717.2 KEP59902.1 - 1.6e-37 129.0 0.0 3.3e-34 118.2 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEP59902.1 - 0.015 15.3 10.6 53 4.2 0.1 6.5 5 0 0 5 5 5 0 HEAT repeat ACDC PF14733.1 KEP59903.1 - 2.9e-22 78.5 0.2 8.4e-22 77.1 0.0 1.8 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.15 KEP59903.1 - 1.6e-13 50.5 9.3 2.5e-08 33.9 0.1 3.4 3 1 0 3 3 3 2 AP2 domain BRF1 PF07741.8 KEP59903.1 - 0.3 11.3 0.7 1.1 9.5 0.5 2.0 1 0 0 1 1 1 0 Brf1-like TBP-binding domain AAA PF00004.24 KEP59904.1 - 8.8e-50 168.3 0.0 1.1e-42 145.3 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEP59904.1 - 1.1e-09 39.0 0.1 0.00027 21.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KEP59904.1 - 7.1e-09 35.0 0.0 1.3e-05 24.3 0.0 2.5 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEP59904.1 - 4.8e-08 33.2 0.1 0.0014 18.7 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEP59904.1 - 5.5e-07 29.4 0.2 0.046 13.4 0.1 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEP59904.1 - 9.6e-07 28.7 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEP59904.1 - 3.1e-06 27.3 2.4 0.062 13.2 0.1 3.6 2 1 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 KEP59904.1 - 6.1e-06 26.1 0.0 0.034 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEP59904.1 - 1.1e-05 25.7 0.0 0.014 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 KEP59904.1 - 1.7e-05 23.7 0.1 0.0041 15.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 KEP59904.1 - 8.6e-05 22.0 0.0 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 KEP59904.1 - 0.00011 21.8 3.1 0.015 15.0 0.1 3.8 3 0 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 KEP59904.1 - 0.00018 20.9 1.0 0.01 15.2 0.1 3.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEP59904.1 - 0.00026 20.2 1.0 0.041 13.0 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI SKI PF01202.17 KEP59904.1 - 0.00068 19.5 0.1 0.68 9.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate kinase RNA_helicase PF00910.17 KEP59904.1 - 0.0008 19.5 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 KEP59904.1 - 0.00092 19.2 0.0 0.69 9.9 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 KEP59904.1 - 0.00099 18.2 0.1 0.074 12.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin UPF0079 PF02367.12 KEP59904.1 - 0.001 18.6 0.1 0.46 10.1 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KEP59904.1 - 0.0049 16.8 0.1 0.028 14.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KEP59904.1 - 0.0061 16.0 0.1 2.8 7.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 KEP59904.1 - 0.0078 15.1 0.0 0.46 9.3 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KEP59904.1 - 0.0079 16.4 0.0 0.27 11.5 0.0 2.6 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.7 KEP59904.1 - 0.0099 15.5 0.8 3.8 7.1 0.1 3.0 3 0 0 3 3 2 1 NACHT domain T2SE PF00437.15 KEP59904.1 - 0.011 14.5 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 KEP59904.1 - 0.012 15.3 0.1 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_3 PF07726.6 KEP59904.1 - 0.02 14.5 0.0 0.24 11.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KEP59904.1 - 0.02 14.4 0.1 0.85 9.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.9 KEP59904.1 - 0.025 14.4 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KEP59904.1 - 0.026 13.7 0.0 0.095 11.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 KEP59904.1 - 0.039 13.0 0.1 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.1 KEP59904.1 - 0.069 12.6 1.8 4.1 6.9 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KEP59904.1 - 0.075 11.8 0.6 5.7 5.6 0.0 2.9 4 0 0 4 4 4 0 NB-ARC domain Arch_ATPase PF01637.13 KEP59904.1 - 0.18 11.4 0.1 21 4.7 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Parvo_NS1 PF01057.12 KEP59904.1 - 0.18 10.6 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Radial_spoke PF04712.7 KEP59905.1 - 8.7e-18 64.3 0.1 9.2e-06 24.6 0.0 3.2 1 1 1 3 3 3 3 Radial spokehead-like protein Myosin_head PF00063.16 KEP59906.1 - 2.5e-170 567.9 0.0 3.5e-170 567.3 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Dynein_light PF01221.13 KEP59906.1 - 7.7e-05 22.6 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 1 Dynein light chain type 1 AAA_22 PF13401.1 KEP59906.1 - 0.022 14.9 0.0 0.087 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEP59906.1 - 0.029 13.4 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 KEP59906.1 - 0.085 13.1 0.2 0.43 10.8 0.1 2.3 1 1 1 2 2 2 0 ABC transporter AAA_10 PF12846.2 KEP59906.1 - 0.092 12.1 0.1 0.4 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 KEP59906.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UCH PF00443.24 KEP59907.1 - 2e-26 92.7 0.0 5.9e-26 91.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP59907.1 - 6.5e-09 35.6 0.7 0.00036 20.0 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KEP59907.1 - 0.0011 19.3 0.0 0.034 14.5 0.0 2.7 2 0 0 2 2 2 1 DUSP domain DUF1561 PF07598.6 KEP59907.1 - 8 4.2 0.0 12 3.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) ERG2_Sigma1R PF04622.7 KEP59909.1 - 0.19 10.9 0.0 0.6 9.3 0.0 1.7 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein S6PP PF05116.8 KEP59913.1 - 5e-38 130.7 0.0 2e-16 60.0 0.0 4.2 3 1 1 4 4 4 3 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 KEP59913.1 - 1.1e-12 48.0 0.0 9.3e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP59913.1 - 0.022 14.9 0.3 5.3 7.1 0.0 2.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase ASXH PF13919.1 KEP59913.1 - 0.062 13.0 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Asx homology domain PCI PF01399.22 KEP59915.1 - 1.2e-10 41.5 0.0 9.3e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 PCI domain ETF PF01012.16 KEP59915.1 - 0.2 11.3 3.0 0.37 10.4 2.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain S1 PF00575.18 KEP59917.1 - 2e-17 63.0 0.0 2.6e-05 24.2 0.0 4.5 4 0 0 4 4 4 3 S1 RNA binding domain B12-binding_2 PF02607.12 KEP59917.1 - 0.0037 17.2 0.4 0.016 15.1 0.3 2.2 1 0 0 1 1 1 1 B12 binding domain BNIP3 PF06553.7 KEP59919.1 - 2.2 7.5 4.6 0.76 9.1 0.4 1.9 2 0 0 2 2 2 0 BNIP3 Sec20 PF03908.8 KEP59920.1 - 2.7e-15 55.8 0.3 6.9e-15 54.5 0.2 1.7 1 0 0 1 1 1 1 Sec20 DASH_Dam1 PF08653.5 KEP59920.1 - 0.27 11.0 2.1 0.56 10.0 0.1 2.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 MMR_HSR1 PF01926.18 KEP59923.1 - 3e-15 56.1 0.0 4.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP59923.1 - 1e-06 28.3 0.1 0.00091 18.7 0.0 2.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEP59923.1 - 2.7e-05 23.4 0.0 4.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEP59923.1 - 0.00046 20.0 0.1 0.017 14.9 0.1 2.2 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.5 KEP59923.1 - 0.00068 18.8 0.0 0.00099 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KEP59923.1 - 0.0009 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KEP59923.1 - 0.028 14.8 0.0 0.052 14.0 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein Septin PF00735.13 KEP59923.1 - 0.048 12.6 0.1 3.1 6.7 0.0 2.3 1 1 0 1 1 1 0 Septin adh_short PF00106.20 KEP59925.1 - 4e-44 150.4 0.4 6.8e-44 149.7 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEP59925.1 - 8.3e-29 101.0 0.1 1.2e-28 100.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEP59925.1 - 4.8e-23 81.7 0.1 8.7e-23 80.9 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEP59925.1 - 0.00034 20.1 0.3 0.00077 18.9 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Seadorna_Vp10 PF07322.6 KEP59925.1 - 0.0028 16.9 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus Vp10 Eno-Rase_NADH_b PF12242.3 KEP59925.1 - 0.011 15.5 0.6 0.022 14.5 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KEP59925.1 - 0.024 13.7 0.0 0.097 11.7 0.0 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Ribosomal_S5 PF00333.15 KEP59925.1 - 1.1 9.0 5.6 1.7 8.4 0.7 2.4 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain WD40 PF00400.27 KEP59926.1 - 1.9e-05 24.3 0.8 0.25 11.2 0.0 3.4 2 0 0 2 2 2 2 WD domain, G-beta repeat DnaJ PF00226.26 KEP59928.1 - 1e-19 70.0 1.7 1.6e-19 69.3 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 KEP59928.1 - 7.9e-11 41.5 0.0 7.5e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KEP59928.1 - 2.7e-05 24.3 0.6 0.064 13.4 0.1 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEP59928.1 - 2.9e-05 24.1 0.2 0.2 11.7 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin-like DUF836 PF05768.9 KEP59928.1 - 0.00075 19.7 1.7 0.083 13.1 0.2 2.6 3 0 0 3 3 3 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 KEP59928.1 - 0.024 14.6 0.3 3.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin AP2 PF00847.15 KEP59929.1 - 5e-07 29.7 2.2 1.1e-06 28.6 1.5 1.6 1 0 0 1 1 1 1 AP2 domain Exostosin PF03016.10 KEP59931.1 - 9.4e-11 41.2 0.0 1.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Spore_III_AB PF09548.5 KEP59931.1 - 0.45 10.2 0.6 1.1 8.9 0.4 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Hpr_kinase_C PF07475.7 KEP59932.1 - 0.25 10.6 0.0 0.45 9.7 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Ribosomal_S6 PF01250.12 KEP59933.1 - 4.2e-13 48.9 0.1 6.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 Alba PF01918.16 KEP59934.1 - 0.00052 19.5 0.1 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 Alba GAS PF13851.1 KEP59935.1 - 5.3e-52 175.9 33.6 5.3e-52 175.9 23.3 3.4 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Bromo_TP PF07524.8 KEP59935.1 - 0.26 11.0 2.3 0.52 10.0 0.2 2.4 2 0 0 2 2 2 0 Bromodomain associated RPAP3_C PF13877.1 KEP59937.1 - 0.0096 15.8 0.4 0.46 10.4 0.0 3.5 3 0 0 3 3 3 1 Potential Monad-binding region of RPAP3 TPR_19 PF14559.1 KEP59937.1 - 0.077 13.3 0.1 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat eIF-1a PF01176.14 KEP59938.1 - 2.6e-06 26.7 0.0 6.5e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Translation initiation factor 1A / IF-1 Nucleoside_tran PF01733.13 KEP59939.1 - 0.0053 15.9 0.6 0.02 14.0 0.0 2.1 2 0 0 2 2 2 1 Nucleoside transporter Pkinase PF00069.20 KEP59940.1 - 3.1e-64 216.6 0.0 2.3e-63 213.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain EF-hand_7 PF13499.1 KEP59940.1 - 1.2e-30 105.3 3.1 4.1e-13 49.2 0.5 3.6 3 0 0 3 3 3 3 EF-hand domain pair Pkinase_Tyr PF07714.12 KEP59940.1 - 2.2e-27 95.7 0.0 1.3e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP59940.1 - 4e-26 88.2 9.5 2.3e-08 32.7 0.3 5.5 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 KEP59940.1 - 3.3e-25 85.6 5.7 0.0002 20.9 0.0 5.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KEP59940.1 - 2e-19 68.9 7.7 3.9e-11 42.3 0.2 4.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KEP59940.1 - 1.9e-12 45.9 10.1 0.00012 21.2 0.1 4.5 4 1 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 KEP59940.1 - 5.2e-05 22.9 2.6 0.072 12.8 0.0 4.0 2 1 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand APH PF01636.18 KEP59940.1 - 0.00034 20.4 0.2 0.00089 19.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEP59940.1 - 0.0017 17.4 0.0 0.0037 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.4 KEP59940.1 - 0.0068 16.4 0.2 2 8.4 0.0 2.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Choline_kinase PF01633.15 KEP59940.1 - 0.021 14.4 0.2 0.82 9.2 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ribosomal_L17 PF01196.14 KEP59941.1 - 1.1e-24 86.8 0.0 1.7e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 RNA_pol_Rpc34 PF05158.7 KEP59942.1 - 2.6e-43 148.4 4.0 6.7e-35 120.8 0.0 3.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 KEP59942.1 - 0.0047 16.7 0.1 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC UBA_3 PF09288.5 KEP59942.1 - 0.053 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Ribosomal_S27e PF01667.12 KEP59943.1 - 2.1e-26 91.2 8.3 2.6e-26 90.9 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KEP59943.1 - 0.038 13.8 2.2 0.052 13.4 1.5 1.3 1 1 0 1 1 1 0 IBR domain Zn_Tnp_IS1 PF03811.8 KEP59943.1 - 0.33 10.4 2.1 1.5 8.3 1.5 2.1 1 1 0 1 1 1 0 InsA N-terminal domain Tnp_zf-ribbon_2 PF13842.1 KEP59943.1 - 0.78 10.2 4.0 1.9 8.9 2.8 1.8 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RNA_pol_N PF01194.12 KEP59944.1 - 7.4e-30 102.7 0.6 9.3e-30 102.4 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF4616 PF15394.1 KEP59945.1 - 0.31 9.9 3.0 0.4 9.6 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Hexapep PF00132.19 KEP59946.1 - 1.1e-08 34.1 10.1 0.0028 17.0 0.2 4.3 3 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEP59946.1 - 0.3 10.7 7.4 1.8 8.1 0.8 3.5 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase RRM_1 PF00076.17 KEP59947.1 - 1.4e-26 91.8 0.0 3.4e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP59947.1 - 1.2e-14 53.9 0.0 1.5e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP59947.1 - 2.3e-09 36.9 0.0 6.5e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box_2 PF09011.5 KEP59951.1 - 5.5e-26 90.7 6.9 1e-25 89.8 4.8 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 KEP59951.1 - 4.5e-09 36.4 8.5 6.7e-09 35.9 4.6 2.3 1 1 1 2 2 2 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.18 KEP59951.1 - 1.3e-05 25.2 0.1 3.7e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SUZ PF12752.2 KEP59951.1 - 0.053 14.0 2.2 0.29 11.7 1.5 2.3 1 0 0 1 1 1 0 SUZ domain Striatin PF08232.7 KEP59952.1 - 0.075 13.3 0.3 0.093 13.0 0.2 1.1 1 0 0 1 1 1 0 Striatin family tRNA-synt_1c PF00749.16 KEP59955.1 - 8.6e-98 326.8 0.0 8.6e-98 326.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEP59955.1 - 3e-49 167.0 0.0 5.4e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KEP59955.1 - 0.0043 17.4 0.0 0.0043 17.4 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEP59955.1 - 0.05 13.5 0.2 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tbf5 PF06331.7 KEP59956.1 - 3.6e-19 68.2 0.2 4.7e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF3505 PF12013.3 KEP59956.1 - 0.091 13.0 1.0 0.11 12.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) HCNGP PF07818.8 KEP59957.1 - 2.3e-19 69.2 0.0 3.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein Serpin PF00079.15 KEP59958.1 - 2.3e-63 214.6 0.0 2.8e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) PSII_Pbs27 PF13326.1 KEP59958.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 DUF1469 PF07332.6 KEP59960.1 - 0.0052 16.5 4.6 0.011 15.3 3.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) VirB3 PF05101.8 KEP59960.1 - 0.26 11.2 2.5 0.64 10.0 1.7 1.6 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein PIRT PF15099.1 KEP59961.1 - 0.92 8.7 10.1 1.7 7.8 2.2 3.3 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family IL6 PF00489.12 KEP59964.1 - 0.00018 21.1 0.5 0.00036 20.1 0.3 1.5 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family Noc2 PF03715.8 KEP59964.1 - 0.031 13.1 0.2 0.063 12.1 0.2 1.4 1 0 0 1 1 1 0 Noc2p family MT-A70 PF05063.9 KEP59967.1 - 2e-54 183.8 0.4 2.7e-54 183.3 0.3 1.2 1 0 0 1 1 1 1 MT-A70 NOC3p PF07540.6 KEP59970.1 - 4.7e-08 33.1 0.0 0.35 11.1 0.1 3.7 3 0 0 3 3 3 3 Nucleolar complex-associated protein FYDLN_acid PF09538.5 KEP59972.1 - 1.8 9.1 22.8 2 9.0 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) UDPGP PF01704.13 KEP59974.1 - 4.2e-11 42.0 0.0 2e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase Dzip-like_N PF13815.1 KEP59974.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Kinesin PF00225.18 KEP59975.1 - 7.4e-104 347.0 0.0 7.4e-104 347.0 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain KIF1B PF12423.3 KEP59975.1 - 2.2e-07 30.7 2.3 4.9e-07 29.6 0.4 2.7 2 0 0 2 2 2 1 Kinesin protein 1B OmpH PF03938.9 KEP59975.1 - 0.00016 21.6 10.0 0.00016 21.6 6.9 3.0 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) FHA PF00498.21 KEP59975.1 - 0.0099 15.9 0.0 0.032 14.3 0.0 1.9 1 0 0 1 1 1 1 FHA domain IncA PF04156.9 KEP59975.1 - 5.2 6.6 24.1 0.41 10.2 2.5 2.6 2 0 0 2 2 2 0 IncA protein DUF3697 PF12478.3 KEP59977.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Pkinase PF00069.20 KEP59978.1 - 7.7e-76 254.6 0.0 8.7e-76 254.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP59978.1 - 2.5e-32 111.9 0.0 3.2e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP59978.1 - 0.0015 17.5 0.0 0.0029 16.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEP59978.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP59978.1 - 0.019 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEP59978.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.4 1 1 1 2 2 2 0 RIO1 family SET PF00856.23 KEP59979.1 - 3.6e-05 24.1 0.2 0.00066 20.0 0.0 2.8 2 1 1 3 3 3 1 SET domain TAP42 PF04177.7 KEP59981.1 - 2.9e-51 174.4 0.0 4e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 TAP42-like family Histone PF00125.19 KEP59982.1 - 5.9e-34 116.0 0.3 9.4e-34 115.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KEP59982.1 - 4.9e-05 23.4 0.0 7.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEP59982.1 - 0.014 15.4 0.1 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 KEP59982.1 - 0.049 13.4 0.2 0.098 12.4 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Porin_3 PF01459.17 KEP59984.1 - 2.9e-29 102.2 0.2 3.6e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin WD40 PF00400.27 KEP59985.1 - 2e-20 71.8 17.3 1.7e-07 30.8 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KEP59985.1 - 7.7e-06 24.9 3.4 0.096 11.4 0.3 5.2 5 1 0 5 5 5 2 Coatomer WD associated region PHTB1_N PF14727.1 KEP59985.1 - 0.003 16.5 0.0 0.006 15.5 0.0 1.4 1 0 0 1 1 1 1 PTHB1 N-terminus SusD PF07980.6 KEP59985.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 SusD family TPR_19 PF14559.1 KEP59985.1 - 0.46 10.8 5.0 5.6 7.3 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-CCCH PF00642.19 KEP59986.1 - 4.3e-14 51.7 19.5 1.5e-05 24.5 2.3 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TSP_1 PF00090.14 KEP59987.1 - 1.3e-05 25.2 3.6 1.3e-05 25.2 2.5 6.6 5 0 0 5 5 5 3 Thrombospondin type 1 domain zf-CCHC PF00098.18 KEP59988.1 - 3.4e-11 42.5 23.1 0.00012 21.8 0.2 4.7 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 KEP59988.1 - 7.4e-05 22.3 24.8 0.074 12.7 0.8 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 KEP59988.1 - 0.037 13.5 0.8 0.037 13.5 0.6 4.0 2 1 2 4 4 4 0 Zinc knuckle Nup88 PF10168.4 KEP59988.1 - 5.6 4.6 9.4 7.9 4.1 6.5 1.1 1 0 0 1 1 1 0 Nuclear pore component zf-CCHC_3 PF13917.1 KEP59988.1 - 5.7 6.7 22.4 25 4.6 0.1 4.7 3 1 0 3 3 3 0 Zinc knuckle zf-CCCH PF00642.19 KEP59989.1 - 5.5e-08 32.2 17.3 0.00016 21.2 0.5 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.10 KEP59989.1 - 0.028 13.8 0.3 0.073 12.6 0.2 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region RGCC PF15151.1 KEP59989.1 - 6.3 7.2 9.7 0.44 10.9 0.8 3.2 3 0 0 3 3 3 0 Response gene to complement 32 protein family DUF788 PF05620.6 KEP59990.1 - 3.4e-05 23.7 0.0 7.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Hamartin PF04388.7 KEP59990.1 - 2.1 6.9 15.1 3.3 6.2 10.5 1.3 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.20 KEP59991.1 - 1.8e-61 207.5 0.0 3.2e-61 206.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP59991.1 - 1.3e-43 148.9 0.0 2.2e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP59991.1 - 1.6e-06 27.3 0.0 2.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEP59991.1 - 9.7 4.8 0.0 14 4.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_60s PF00428.14 KEP59992.1 - 5.8e-21 74.7 6.0 1.2e-20 73.6 4.1 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.15 KEP59992.1 - 8.1e-21 73.8 0.1 1.4e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 WD40 PF00400.27 KEP59993.1 - 5.6e-54 178.1 14.7 1.8e-10 40.2 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEP59993.1 - 0.00081 18.2 0.2 0.9 8.2 0.0 3.7 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KEP59993.1 - 0.045 11.8 1.5 3.9 5.4 0.0 3.1 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Sulfate_transp PF00916.15 KEP59994.1 - 0.044 12.7 1.1 0.078 11.9 0.8 1.3 1 0 0 1 1 1 0 Sulfate transporter family Thioredoxin PF00085.15 KEP59995.1 - 2.5e-41 139.5 0.0 2.4e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KEP59995.1 - 1.6e-13 50.8 0.0 6.1e-08 32.6 0.0 4.3 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KEP59995.1 - 9.1e-10 38.7 0.0 6.1e-05 23.1 0.0 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEP59995.1 - 9.4e-08 31.9 0.1 2.2e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KEP59995.1 - 7.2e-06 26.0 0.0 0.0014 18.6 0.0 3.1 2 1 0 2 2 2 1 Thioredoxin-like hSac2 PF12456.3 KEP59997.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Inositol phosphatase WD40 PF00400.27 KEP59997.1 - 0.16 11.8 14.6 6.9 6.7 0.6 5.6 5 1 0 5 5 5 0 WD domain, G-beta repeat DUF3843 PF12954.2 KEP59997.1 - 6.7 5.6 0.0 11 4.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Laminin_G_3 PF13385.1 KEP59998.1 - 8.8e-19 68.2 0.0 1.4e-18 67.6 0.0 1.5 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 KEP59998.1 - 0.00032 20.7 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain FXa_inhibition PF14670.1 KEP59999.1 - 4.3e-09 36.3 34.7 4.5e-05 23.4 5.1 3.4 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 KEP59999.1 - 0.00035 20.5 6.4 0.00035 20.5 4.4 3.4 2 1 1 3 3 3 2 Calcium-binding EGF domain EGF PF00008.22 KEP59999.1 - 0.00043 20.1 22.2 0.0021 17.9 4.8 3.8 4 0 0 4 4 4 2 EGF-like domain EGF_3 PF12947.2 KEP59999.1 - 0.013 15.4 27.2 0.03 14.2 1.1 3.7 3 0 0 3 3 3 0 EGF domain cEGF PF12662.2 KEP59999.1 - 0.12 12.0 12.6 0.39 10.3 0.5 3.1 3 0 0 3 3 3 0 Complement Clr-like EGF-like hEGF PF12661.2 KEP59999.1 - 0.79 9.9 8.2 17 5.7 0.3 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF DUF1517 PF07466.6 KEP59999.1 - 1.6 7.6 6.3 1.6 7.6 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) PITH PF06201.8 KEP60000.1 - 2.2e-39 134.6 0.1 2.5e-39 134.4 0.1 1.0 1 0 0 1 1 1 1 PITH domain Peptidase_S9_N PF02897.10 KEP60000.1 - 0.0011 17.6 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain FimH_man-bind PF09160.5 KEP60000.1 - 0.095 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 FimH, mannose binding Abhydrolase_6 PF12697.2 KEP60001.1 - 1.1e-12 48.3 0.5 1.7e-12 47.7 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP60001.1 - 3.6e-10 39.7 0.0 7.3e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEP60001.1 - 6.8e-05 22.1 0.1 0.068 12.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEP60001.1 - 0.0089 15.5 0.2 0.13 11.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEP60001.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase AXE1 PF05448.7 KEP60001.1 - 0.027 12.9 0.2 0.077 11.4 0.1 1.8 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Pkinase PF00069.20 KEP60002.1 - 2.4e-28 99.0 0.1 1.5e-26 93.1 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60002.1 - 1.7e-11 43.6 0.0 4.1e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Carboxyl_trans PF01039.17 KEP60003.1 - 2e-150 501.4 0.0 2.7e-150 500.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 KEP60003.1 - 3.3e-52 177.6 0.0 3.8e-19 68.3 0.0 4.2 4 0 0 4 4 4 4 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 KEP60003.1 - 1.7e-47 161.4 0.3 3.5e-47 160.4 0.2 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KEP60003.1 - 3.8e-26 91.3 0.0 1e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEP60003.1 - 9.3e-22 77.0 0.0 2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KEP60003.1 - 1.6e-14 54.0 0.0 4.6e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KEP60003.1 - 8.2e-10 38.1 0.9 1.4e-09 37.3 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KEP60003.1 - 4.6e-08 32.1 0.0 8.4e-06 24.7 0.0 3.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KEP60003.1 - 8.9e-07 28.4 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KEP60003.1 - 0.0012 18.4 0.1 0.008 15.8 0.1 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.17 KEP60003.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.9 KEP60003.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.1 KEP60003.1 - 2.3 7.2 0.0 4 6.4 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp NOB1_Zn_bind PF08772.6 KEP60004.1 - 1.6e-19 69.5 0.2 3e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Daxx PF03344.10 KEP60004.1 - 0.056 11.9 13.8 0.093 11.2 9.6 1.3 1 0 0 1 1 1 0 Daxx Family DZR PF12773.2 KEP60004.1 - 0.081 12.7 0.2 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KEP60004.1 - 0.088 12.3 0.2 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KEP60004.1 - 0.092 11.9 0.6 0.21 10.8 0.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Hid1 PF12722.2 KEP60004.1 - 0.27 8.8 0.5 0.36 8.4 0.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nudix_N_2 PF14803.1 KEP60004.1 - 0.31 10.7 2.4 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Nudix N-terminal BUD22 PF09073.5 KEP60004.1 - 0.63 9.0 16.7 1.1 8.1 11.6 1.4 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 KEP60004.1 - 1.8 6.1 4.0 2.2 5.8 2.8 1.1 1 0 0 1 1 1 0 Ycf1 NOA36 PF06524.7 KEP60004.1 - 3.6 6.7 8.4 1.9 7.6 4.0 1.7 2 0 0 2 2 2 0 NOA36 protein Nucleoplasmin PF03066.10 KEP60004.1 - 3.6 7.0 16.0 7.9 5.9 11.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin VID27 PF08553.5 KEP60004.1 - 4.4 5.3 8.5 6.1 4.9 5.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 KEP60004.1 - 6.7 4.4 18.4 8.7 4.1 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family SpoU_methylase PF00588.14 KEP60005.1 - 5.6e-26 91.1 0.0 1.1e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF4038 PF13204.1 KEP60005.1 - 1 8.6 0.0 1.7 7.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) PP2C PF00481.16 KEP60006.1 - 2.7e-32 112.1 0.0 5.5e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEP60006.1 - 0.00027 20.4 0.0 0.0013 18.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C RRM_6 PF14259.1 KEP60007.1 - 1.2e-15 57.2 0.1 1.2e-08 34.8 0.0 4.3 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP60007.1 - 5.7e-14 51.5 0.1 7.1e-10 38.3 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP60007.1 - 0.14 12.0 0.4 5.1 7.0 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GNAT_acetyltr_2 PF13718.1 KEP60008.1 - 2.8e-67 225.8 0.0 1.1e-66 223.8 0.0 2.1 2 1 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KEP60008.1 - 4e-58 195.9 0.0 7.7e-58 195.0 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 KEP60008.1 - 1.7e-35 120.5 0.1 6.1e-35 118.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KEP60008.1 - 2.4e-24 85.3 0.2 6.5e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 KEP60008.1 - 0.0028 17.6 0.0 0.0099 15.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Nucleoplasmin PF03066.10 KEP60008.1 - 0.076 12.5 10.7 0.15 11.5 7.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 KEP60008.1 - 0.28 9.6 10.1 0.49 8.8 7.0 1.2 1 0 0 1 1 1 0 Daxx Family TLP-20 PF06088.6 KEP60008.1 - 0.41 10.3 2.7 0.88 9.2 1.9 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Myc_N PF01056.13 KEP60008.1 - 0.42 9.7 5.5 0.82 8.7 3.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 KEP60008.1 - 1.6 6.5 13.5 3.3 5.5 9.3 1.4 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 KEP60008.1 - 3.1 6.9 10.0 7.2 5.7 6.9 1.6 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KEP60008.1 - 3.5 7.9 16.3 8.3 6.7 11.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KEP60008.1 - 7.3 6.9 11.2 22 5.4 7.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 KEP60009.1 - 3.6e-69 232.7 0.0 5.4e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60009.1 - 7.7e-42 143.1 0.1 3.4e-41 141.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP60009.1 - 4.7e-33 109.9 7.5 1.3e-06 27.2 0.2 6.4 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.1 KEP60009.1 - 5.2e-30 103.3 5.0 5.5e-11 42.4 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KEP60009.1 - 5e-23 79.3 12.6 7.9e-06 24.9 0.0 5.8 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.1 KEP60009.1 - 7.2e-23 79.9 12.2 3.2e-08 33.0 0.1 6.3 4 2 2 6 6 6 6 EF-hand domain pair EF-hand_6 PF13405.1 KEP60009.1 - 1.6e-22 77.2 11.0 0.00041 20.0 0.1 6.5 6 0 0 6 6 6 5 EF-hand domain SPARC_Ca_bdg PF10591.4 KEP60009.1 - 6.2e-09 35.8 0.2 0.00025 21.0 0.0 3.6 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.1 KEP60009.1 - 1.6e-07 30.5 0.0 2.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.2 KEP60009.1 - 4.5e-06 26.3 3.4 0.069 12.8 0.2 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.9 KEP60009.1 - 1.8e-05 23.9 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEP60009.1 - 0.0035 16.7 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Excalibur PF05901.6 KEP60009.1 - 0.028 14.7 0.3 16 5.9 0.0 3.3 3 0 0 3 3 3 0 Excalibur calcium-binding domain Choline_kinase PF01633.15 KEP60009.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase C1_3 PF07649.7 KEP60011.1 - 0.17 11.9 0.5 0.17 11.9 0.4 2.0 2 0 0 2 2 2 0 C1-like domain DUF3611 PF12263.3 KEP60011.1 - 0.79 9.0 5.7 0.33 10.3 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Synaptobrevin PF00957.16 KEP60011.1 - 1.4 8.5 6.0 2.8 7.5 0.3 2.9 3 0 0 3 3 3 0 Synaptobrevin Myosin_head PF00063.16 KEP60012.1 - 8.9e-07 27.3 0.0 3.9e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) SNAP PF14938.1 KEP60013.1 - 8.2e-82 274.5 9.3 9.3e-82 274.3 6.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KEP60013.1 - 0.011 15.6 9.3 0.42 10.5 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEP60013.1 - 0.015 15.1 2.4 0.15 12.0 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP60013.1 - 0.026 15.1 13.4 1.3 9.8 0.2 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP60013.1 - 0.026 14.2 7.5 1.1 9.2 0.1 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP60013.1 - 0.053 13.9 9.3 3.9 8.1 0.2 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEP60013.1 - 0.083 13.2 13.0 0.27 11.5 1.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP60013.1 - 0.27 11.2 10.9 1.9 8.6 0.1 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 KEP60013.1 - 0.45 9.3 3.3 4.5 6.0 0.1 2.4 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_16 PF13432.1 KEP60013.1 - 0.52 11.0 16.4 0.85 10.3 1.1 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.22 KEP60014.1 - 1.1e-15 57.0 8.7 4e-07 29.6 0.0 5.9 4 2 0 4 4 4 4 Mitochondrial carrier protein Aminotran_5 PF00266.14 KEP60015.1 - 3.9e-34 117.9 0.0 7.7e-16 57.7 0.0 2.8 3 0 0 3 3 3 2 Aminotransferase class-V EFG_C PF00679.19 KEP60016.1 - 8.9e-16 57.5 0.0 9.1e-15 54.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KEP60016.1 - 3.9e-13 49.0 0.0 7.8e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KEP60016.1 - 0.018 15.1 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Peptidase_S49_N PF08496.5 KEP60017.1 - 2 8.2 4.1 8.3 6.1 0.5 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Tyr_Deacylase PF02580.11 KEP60018.1 - 1.3e-40 138.7 0.0 1.6e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF3897 PF13036.1 KEP60018.1 - 0.04 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) Alba PF01918.16 KEP60019.1 - 2e-05 24.0 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alba Neurochondrin PF05536.6 KEP60020.1 - 3.1e-07 29.1 0.5 2.1e-05 23.0 0.0 3.0 2 1 0 2 2 2 1 Neurochondrin Pex14_N PF04695.8 KEP60020.1 - 0.038 14.0 0.3 0.038 14.0 0.2 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apt1 PF10351.4 KEP60020.1 - 4.2 6.1 16.6 2.5 6.8 2.5 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain MutS_V PF00488.16 KEP60021.1 - 7.8e-17 61.4 0.0 1.1e-10 41.3 0.0 3.4 3 0 0 3 3 3 3 MutS domain V MutS_I PF01624.15 KEP60021.1 - 1.2e-09 38.1 0.0 2.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I GIY-YIG PF01541.19 KEP60021.1 - 0.0015 18.8 0.0 0.0032 17.8 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA_29 PF13555.1 KEP60021.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KEP60021.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_S9 PF00380.14 KEP60022.1 - 7.6e-37 126.2 0.0 1e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PAN_4 PF14295.1 KEP60023.1 - 5.7e-06 25.9 0.6 0.03 14.0 0.0 2.5 2 0 0 2 2 2 2 PAN domain RabGAP-TBC PF00566.13 KEP60024.1 - 4.4e-62 209.3 1.0 6.1e-62 208.8 0.7 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SF-assemblin PF06705.6 KEP60025.1 - 2.3e-60 203.8 32.0 2.6e-60 203.6 22.2 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin TPR_2 PF07719.12 KEP60025.1 - 0.44 10.5 2.3 5.4 7.1 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEP60025.1 - 2.1 8.0 5.0 1.7 8.3 1.2 2.5 2 1 0 2 2 2 0 TPR repeat NPV_P10 PF05531.7 KEP60025.1 - 4.8 7.5 8.4 15 5.9 0.2 3.5 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FliS PF02561.9 KEP60025.1 - 7.2 6.4 13.1 0.21 11.4 1.1 2.9 1 1 2 3 3 3 0 Flagellar protein FliS Amido_AtzD_TrzD PF09663.5 KEP60027.1 - 0.00082 18.0 0.5 0.0014 17.2 0.3 1.3 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Proteasome PF00227.21 KEP60029.1 - 3.3e-48 163.4 0.0 4e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit BTB PF00651.26 KEP60030.1 - 3.7e-15 55.8 0.0 9.3e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Atx10homo_assoc PF09759.4 KEP60033.1 - 2.6e-06 27.0 0.0 0.00057 19.5 0.0 2.7 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain AP2 PF00847.15 KEP60035.1 - 3.5e-22 78.2 34.2 7e-09 35.7 0.3 5.6 5 0 0 5 5 5 5 AP2 domain ACDC PF14733.1 KEP60035.1 - 6.9e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 AP2-coincident C-terminal IL10 PF00726.12 KEP60036.1 - 0.023 14.0 1.4 0.058 12.6 0.2 2.2 2 0 0 2 2 2 0 Interleukin 10 DUF972 PF06156.8 KEP60036.1 - 0.91 9.8 22.0 1.2 9.4 1.5 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF972) SF-assemblin PF06705.6 KEP60036.1 - 1.3 8.0 14.6 0.8 8.7 0.2 3.5 4 0 0 4 4 4 0 SF-assemblin/beta giardin IncA PF04156.9 KEP60036.1 - 3 7.3 35.2 0.49 9.9 4.3 4.0 3 1 0 4 4 4 0 IncA protein TSC22 PF01166.13 KEP60036.1 - 8.2 6.4 14.5 5 7.1 1.0 4.4 5 0 0 5 5 5 0 TSC-22/dip/bun family cNMP_binding PF00027.24 KEP60037.1 - 1.4e-91 300.4 2.6 7.4e-20 70.5 0.0 6.5 6 0 0 6 6 6 6 Cyclic nucleotide-binding domain EF-hand_1 PF00036.27 KEP60037.1 - 0.00014 20.9 3.2 0.019 14.2 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEP60037.1 - 0.0002 20.9 3.8 0.58 10.1 0.1 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KEP60037.1 - 0.00029 20.3 0.9 1.3 8.6 0.1 4.8 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.1 KEP60037.1 - 0.013 15.6 4.9 0.88 9.7 0.2 4.8 6 0 0 6 6 6 0 EF-hand domain pair DUF410 PF04190.8 KEP60038.1 - 1.5e-27 96.8 0.0 2.5e-27 96.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TMEM213 PF15192.1 KEP60038.1 - 0.03 14.3 0.7 0.077 13.0 0.0 1.9 2 0 0 2 2 2 0 TMEM213 family CKS PF01111.14 KEP60039.1 - 3.1e-20 71.7 0.1 9.1e-20 70.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit DUF3435 PF11917.3 KEP60039.1 - 0.035 12.8 0.4 0.056 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) zf-CCCH PF00642.19 KEP60041.1 - 6e-09 35.3 23.2 6.8e-05 22.4 1.5 4.5 4 1 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FIST_C PF10442.4 KEP60042.1 - 0.14 12.0 0.9 0.2 11.5 0.6 1.2 1 0 0 1 1 1 0 FIST C domain Pyr_redox_2 PF07992.9 KEP60043.1 - 7.7e-36 123.8 0.1 1.2e-35 123.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEP60043.1 - 5.2e-31 106.9 0.1 1.7e-30 105.2 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEP60043.1 - 2.4e-15 56.7 3.9 9.9e-12 45.1 0.0 3.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEP60043.1 - 2.2e-07 31.1 1.1 1.3e-06 28.6 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEP60043.1 - 5.1e-07 29.1 3.9 9.9e-07 28.1 2.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KEP60043.1 - 1.5e-06 27.3 4.6 4.2e-06 25.9 0.4 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KEP60043.1 - 7.5e-05 21.7 2.8 0.00028 19.8 1.5 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KEP60043.1 - 0.00028 19.5 1.6 0.00061 18.3 1.1 1.6 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KEP60043.1 - 0.0012 17.9 0.2 0.0022 17.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KEP60043.1 - 0.0013 17.6 15.7 0.0016 17.3 4.3 3.2 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 KEP60043.1 - 0.0014 18.6 3.3 0.0057 16.6 2.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KEP60043.1 - 0.0057 15.8 0.2 1.2 8.2 0.0 2.9 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 KEP60043.1 - 0.011 16.0 0.2 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 KEP60043.1 - 0.031 13.8 0.5 4 6.9 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KEP60043.1 - 0.19 11.4 1.0 9.6 5.9 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 KEP60043.1 - 0.26 10.1 1.6 0.55 9.0 1.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KEP60043.1 - 0.27 10.5 1.4 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KEP60043.1 - 0.28 10.7 4.3 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KEP60043.1 - 0.33 9.9 5.6 2.6 7.0 1.1 2.8 2 1 1 3 3 3 0 FAD binding domain EF1_GNE PF00736.14 KEP60044.1 - 2.2e-30 104.1 4.2 2.2e-30 104.1 2.9 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain PBP1_TM PF14812.1 KEP60044.1 - 3.2 8.1 11.8 9.6 6.6 3.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kri1_C PF12936.2 KEP60045.1 - 3.4e-29 100.6 1.8 3.4e-29 100.6 1.2 3.1 2 0 0 2 2 2 1 KRI1-like family C-terminal Kri1 PF05178.7 KEP60045.1 - 2.4e-21 75.9 8.6 2.4e-21 75.9 5.9 5.0 4 1 1 5 5 5 1 KRI1-like family ZZ PF00569.12 KEP60045.1 - 1.1e-05 24.8 5.1 2.3e-05 23.8 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.15 KEP60045.1 - 0.0096 15.6 2.3 0.024 14.3 1.6 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) PH PF00169.24 KEP60046.1 - 0.00081 19.5 0.1 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 PH domain EF-hand_7 PF13499.1 KEP60047.1 - 0.00011 22.2 5.2 0.059 13.5 0.0 3.6 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 KEP60047.1 - 0.00019 21.0 0.1 1.3 8.6 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP60047.1 - 0.00027 20.5 0.6 2.3 8.3 0.0 4.1 5 0 0 5 5 5 1 EF-hand domain Acetyltransf_1 PF00583.19 KEP60050.1 - 3.8e-07 30.0 0.1 9.1e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEP60050.1 - 1.1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEP60050.1 - 6.3e-05 22.8 0.1 0.00015 21.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP60050.1 - 0.06 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein CS PF04969.11 KEP60051.1 - 1e-11 45.1 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 CS domain DEAD PF00270.24 KEP60052.1 - 1.5e-41 141.6 0.1 2.7e-40 137.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP60052.1 - 5.7e-22 77.3 0.0 1.3e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KEP60052.1 - 4.4e-05 22.0 0.0 0.011 14.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 KEP60052.1 - 0.44 10.6 3.7 0.56 10.3 0.1 2.9 3 1 0 3 3 3 0 AAA domain Ank_2 PF12796.2 KEP60053.1 - 2.6e-31 107.8 4.4 3.4e-13 49.7 0.1 3.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEP60053.1 - 2.9e-26 89.9 11.1 1.5e-06 27.7 0.2 6.4 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 KEP60053.1 - 7.3e-25 84.5 1.8 2e-05 24.3 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KEP60053.1 - 1e-23 83.2 1.4 1.8e-09 37.8 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEP60053.1 - 4.1e-20 71.3 9.3 4.6e-07 29.8 0.2 4.8 3 2 1 4 4 4 4 Ankyrin repeats (many copies) DUF2520 PF10728.4 KEP60053.1 - 0.38 10.2 5.2 0.91 8.9 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) DUF2997 PF11211.3 KEP60054.1 - 0.095 12.0 0.1 0.67 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) AMP-binding PF00501.23 KEP60056.1 - 1.9e-38 131.9 0.0 2.7e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEP60056.1 - 5.6e-12 46.4 0.0 1.2e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MOZART2 PF12926.2 KEP60056.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated PTH2 PF01981.11 KEP60057.1 - 7.2e-13 48.2 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Acetyltransf_1 PF00583.19 KEP60059.1 - 2.2e-07 30.8 0.0 5.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEP60059.1 - 0.0058 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEP60059.1 - 0.022 14.9 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEP60059.1 - 0.027 14.5 0.0 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain E1-E2_ATPase PF00122.15 KEP60060.1 - 1e-22 80.3 3.5 1e-22 80.3 2.5 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KEP60060.1 - 5.2e-16 59.7 0.0 3.2e-06 27.7 0.0 3.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP60060.1 - 4.9e-10 39.8 0.0 5.2e-07 30.0 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP60060.1 - 0.0017 18.2 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEP60060.1 - 5.8 6.4 0.1 87 2.5 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3273 PF11677.3 KEP60061.1 - 1.2e-77 260.8 13.0 1.6e-77 260.3 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Actin PF00022.14 KEP60063.1 - 1.3e-94 316.9 0.0 1.5e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 Actin F_actin_cap_B PF01115.12 KEP60064.1 - 8.1e-74 247.8 0.0 9.4e-74 247.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit zf-RanBP PF00641.13 KEP60065.1 - 2.9e-13 48.6 20.8 7.7e-08 31.3 3.6 2.2 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Apt1 PF10351.4 KEP60065.1 - 0.09 11.6 0.7 0.094 11.5 0.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DZR PF12773.2 KEP60065.1 - 1.2 8.9 10.6 1.5 8.6 1.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon HSP70 PF00012.15 KEP60066.1 - 3.3e-109 365.4 0.0 3.9e-100 335.5 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KEP60066.1 - 0.00017 20.2 0.0 0.00098 17.8 0.0 2.1 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KEP60066.1 - 0.00032 20.3 0.0 0.00091 18.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain tRNA-synt_2b PF00587.20 KEP60069.1 - 9.2e-21 74.1 0.0 1.4e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEP60069.1 - 0.032 14.1 0.0 0.08 12.9 0.0 1.7 1 1 0 1 1 1 0 Anticodon binding domain Beta-Casp PF10996.3 KEP60071.1 - 1.6e-07 31.3 0.0 0.0006 19.7 0.0 2.5 2 0 0 2 2 2 2 Beta-Casp domain Lactamase_B PF00753.22 KEP60071.1 - 0.0019 17.8 0.0 1.4 8.4 0.0 2.7 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEP60071.1 - 0.006 16.1 0.0 0.055 13.0 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.27 KEP60072.1 - 4.3e-24 83.4 16.6 1.8e-05 24.4 0.1 10.3 11 0 0 11 11 11 7 WD domain, G-beta repeat EF-hand_6 PF13405.1 KEP60072.1 - 0.26 11.2 0.1 8.9 6.5 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 KEP60072.1 - 0.5 10.0 0.0 2.1 8.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Diphthamide_syn PF01866.12 KEP60073.1 - 4.8e-16 58.8 0.2 3.1e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Peptidase_S9 PF00326.16 KEP60075.1 - 7.9e-12 44.8 0.0 1.8e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family MMR_HSR1 PF01926.18 KEP60078.1 - 5.7e-11 42.4 0.0 4.6e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP60078.1 - 2.9e-06 26.6 0.1 0.11 11.7 0.0 2.8 2 1 1 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEP60078.1 - 0.002 17.5 0.0 0.8 9.1 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEP60078.1 - 0.0077 16.0 0.1 2.9 7.7 0.0 3.0 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 KEP60078.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEP60078.1 - 0.025 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphoprotein PF00922.12 KEP60078.1 - 5.8 6.0 5.3 8.4 5.5 3.6 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Methyltransf_31 PF13847.1 KEP60079.1 - 5e-13 48.9 0.0 9.8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP60079.1 - 1.7e-12 47.9 0.0 4.9e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP60079.1 - 2.3e-11 43.7 0.0 4.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEP60079.1 - 3.8e-10 39.3 0.1 6.1e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KEP60079.1 - 5.2e-10 39.6 0.0 1.2e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEP60079.1 - 7.2e-06 25.4 0.2 1.3e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 KEP60079.1 - 8.3e-06 24.9 0.1 1.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 KEP60079.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP60079.1 - 1.6e-05 25.2 0.1 5.5e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KEP60079.1 - 0.00014 20.7 0.0 0.00021 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KEP60079.1 - 0.0005 20.4 0.0 0.00092 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEP60079.1 - 0.00056 19.0 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KEP60079.1 - 0.001 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KEP60079.1 - 0.0012 18.3 0.1 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 KEP60079.1 - 0.0031 17.0 0.1 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.8 KEP60079.1 - 0.0045 16.3 0.1 0.0081 15.4 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 KEP60079.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KEP60079.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 KEP60079.1 - 0.082 13.7 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KEP60079.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 2 0 0 2 2 1 0 FtsJ-like methyltransferase GidB PF02527.10 KEP60079.1 - 0.11 11.6 0.2 0.23 10.5 0.1 1.5 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_3 PF01596.12 KEP60079.1 - 0.13 11.2 0.2 0.26 10.3 0.1 1.5 1 1 0 1 1 1 0 O-methyltransferase zf-RING-like PF08746.6 KEP60080.1 - 0.01 15.8 0.9 0.01 15.8 0.6 2.0 2 0 0 2 2 2 0 RING-like domain zf-TFIIB PF13453.1 KEP60080.1 - 0.075 12.2 2.5 0.22 10.7 0.0 2.6 3 0 0 3 3 3 0 Transcription factor zinc-finger Prok-RING_1 PF14446.1 KEP60080.1 - 0.15 11.7 3.2 0.2 11.4 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 KEP60080.1 - 0.16 11.9 1.4 0.5 10.3 1.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain tRNA-synt_2c PF01411.14 KEP60081.1 - 8.2e-202 671.3 0.0 1e-201 671.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KEP60081.1 - 1.5e-14 53.5 0.0 3.3e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain zf-PHD-like PF15446.1 KEP60081.1 - 0.2 10.9 0.1 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain 2-oxoacid_dh PF00198.18 KEP60082.1 - 9.8e-80 267.1 0.1 1.4e-79 266.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEP60082.1 - 1.5e-19 69.3 0.6 3.8e-19 68.0 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KEP60082.1 - 9e-07 28.4 6.3 1.3e-05 24.7 0.2 2.8 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD PF00529.15 KEP60082.1 - 0.00054 19.3 1.4 0.003 16.9 0.2 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 KEP60082.1 - 0.0019 17.4 0.0 0.034 13.2 0.0 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KEP60082.1 - 0.0095 16.2 1.1 0.95 9.8 0.2 2.3 1 1 1 2 2 2 2 HlyD family secretion protein PYNP_C PF07831.8 KEP60082.1 - 0.02 14.3 0.1 2.6 7.5 0.0 2.5 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain TIP49 PF06068.8 KEP60083.1 - 9.6e-180 597.5 0.9 1.1e-179 597.2 0.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KEP60083.1 - 9.1e-10 38.8 0.1 1.6e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP60083.1 - 6.9e-07 29.4 0.0 5.8e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KEP60083.1 - 3.7e-06 26.1 0.4 0.00021 20.4 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEP60083.1 - 7.4e-06 26.1 0.0 0.045 13.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEP60083.1 - 0.00065 19.4 0.0 0.054 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEP60083.1 - 0.0018 17.5 0.4 0.042 13.0 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEP60083.1 - 0.002 17.8 0.1 0.0061 16.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DBI_PRT PF02277.12 KEP60083.1 - 0.0021 17.2 1.3 0.0038 16.3 0.9 1.4 1 0 0 1 1 1 1 Phosphoribosyltransferase AAA_25 PF13481.1 KEP60083.1 - 0.0044 16.4 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KEP60083.1 - 0.0086 15.5 0.2 3.9 6.9 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 KEP60083.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEP60083.1 - 0.023 14.0 0.2 0.073 12.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 KEP60083.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEP60083.1 - 0.038 14.8 0.0 0.088 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEP60083.1 - 0.048 13.2 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Archease PF01951.11 KEP60083.1 - 0.063 13.2 0.3 2.1 8.2 0.1 2.5 2 1 0 2 2 2 0 Archease protein family (MTH1598/TM1083) PhoH PF02562.11 KEP60083.1 - 0.066 12.4 0.4 0.16 11.1 0.3 1.6 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 KEP60083.1 - 0.098 12.2 0.1 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 KEP60083.1 - 0.11 11.2 0.6 0.57 8.9 0.1 2.0 2 0 0 2 2 2 0 AFG1-like ATPase Mg_chelatase_2 PF13335.1 KEP60083.1 - 0.13 12.6 0.7 0.64 10.4 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_pol_Rpc4 PF05132.9 KEP60084.1 - 9e-12 45.1 4.3 8.7e-06 25.7 0.0 3.8 3 1 0 3 3 3 2 RNA polymerase III RPC4 FtsJ PF01728.14 KEP60086.1 - 1.6e-08 34.7 0.4 4.2e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase S4 PF01479.20 KEP60086.1 - 0.034 13.5 0.1 0.077 12.4 0.1 1.6 1 0 0 1 1 1 0 S4 domain Flavodoxin_1 PF00258.20 KEP60087.1 - 1.7e-16 60.5 0.0 3.5e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEP60087.1 - 3.4e-16 59.7 0.0 1e-15 58.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 KEP60087.1 - 2e-05 24.1 0.0 0.0078 15.6 0.0 2.8 2 1 1 3 3 3 2 FAD binding domain NAD_binding_6 PF08030.7 KEP60087.1 - 0.22 11.4 0.0 0.71 9.7 0.0 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain zf-C3HC4_3 PF13920.1 KEP60088.1 - 4.9e-10 38.9 7.2 9.5e-10 38.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP60088.1 - 0.0026 17.4 9.1 0.0059 16.3 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP60088.1 - 0.027 14.4 10.5 0.059 13.4 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MS_channel PF00924.13 KEP60089.1 - 4e-14 52.4 0.3 6.1e-14 51.8 0.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel ABC_membrane PF00664.18 KEP60090.1 - 1.9 7.8 0.0 3.6 6.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region zf-CCCH PF00642.19 KEP60091.1 - 2.1e-14 52.7 18.5 4.2e-06 26.3 0.4 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.10 KEP60091.1 - 5.3 6.7 10.2 0.54 9.8 0.1 3.4 4 0 0 4 4 4 0 Ataxin-2 C-terminal region BCDHK_Adom3 PF10436.4 KEP60093.1 - 1.4e-22 79.9 0.0 2.4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEP60093.1 - 3.7e-10 39.5 0.0 0.00033 20.3 0.0 2.8 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MCM PF00493.18 KEP60095.1 - 3.9e-120 400.6 0.0 8.2e-120 399.5 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEP60095.1 - 5.7e-11 42.9 0.0 3e-10 40.6 0.0 2.2 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEP60095.1 - 1.6e-06 27.4 0.1 5.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEP60095.1 - 4e-05 23.3 0.0 0.00015 21.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEP60095.1 - 0.00055 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEP60095.1 - 0.0058 16.1 0.1 0.84 9.0 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain EzrA PF06160.7 KEP60096.1 - 0.14 10.3 13.8 0.2 9.8 9.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TIP120 PF08623.5 KEP60096.1 - 0.16 11.5 2.5 0.65 9.5 1.6 2.1 1 1 0 1 1 1 0 TATA-binding protein interacting (TIP20) Rad9 PF04139.8 KEP60096.1 - 0.28 10.2 2.4 0.47 9.5 1.7 1.2 1 0 0 1 1 1 0 Rad9 DUF1664 PF07889.7 KEP60096.1 - 3.2 7.5 10.6 9.4 6.0 2.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KEP60096.1 - 3.8 7.3 14.8 3.8 7.3 4.9 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GNT-I PF03071.10 KEP60096.1 - 6.5 5.1 5.3 11 4.3 3.7 1.3 1 0 0 1 1 1 0 GNT-I family Ras PF00071.17 KEP60097.1 - 5.8e-54 181.8 0.1 6.9e-54 181.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP60097.1 - 2.3e-20 73.2 0.0 3.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP60097.1 - 7.5e-13 48.0 0.0 9.6e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEP60097.1 - 4.3e-08 32.8 0.0 9.7e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEP60097.1 - 0.00022 21.1 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KEP60097.1 - 0.0012 18.0 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Nucleo_P87 PF07267.6 KEP60099.1 - 6.3 5.3 3.9 12 4.4 2.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cytochrom_C PF00034.16 KEP60101.1 - 2.3e-11 44.3 0.1 3.7e-11 43.6 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KEP60101.1 - 9.8e-07 28.8 2.8 3e-06 27.2 2.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KEP60101.1 - 0.00024 20.5 0.1 0.001 18.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 KEP60101.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C1 family Cytochrome-c551 PF10643.4 KEP60101.1 - 0.064 12.5 0.1 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Acetyltransf_1 PF00583.19 KEP60102.1 - 1.2e-12 47.6 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEP60102.1 - 9.3e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP60102.1 - 0.00013 21.5 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KEP60102.1 - 0.00067 19.7 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEP60102.1 - 0.024 14.4 0.2 0.048 13.5 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosom_S12_S23 PF00164.20 KEP60103.1 - 1.3e-37 127.9 1.3 1.9e-37 127.3 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Neuregulin PF02158.10 KEP60103.1 - 2.2 6.9 15.2 0.32 9.7 7.7 1.6 1 1 0 1 1 1 0 Neuregulin family PRP3 PF08572.5 KEP60104.1 - 7.3e-53 179.2 11.6 7.3e-53 179.2 8.0 2.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KEP60104.1 - 7.5e-27 93.5 1.3 1.4e-26 92.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) ATP-synt_ab PF00006.20 KEP60105.1 - 3e-59 200.1 0.0 4e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEP60105.1 - 9.5e-18 64.7 0.3 2e-17 63.6 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEP60105.1 - 1.1e-10 41.5 0.9 2.1e-10 40.6 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KEP60105.1 - 0.013 15.3 0.2 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain ubiquitin PF00240.18 KEP60108.1 - 3.9e-139 452.2 23.6 2.9e-34 116.2 0.3 5.0 4 1 1 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 KEP60108.1 - 1.3e-76 252.2 20.5 1.6e-19 69.3 0.3 5.0 3 2 2 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEP60108.1 - 3.2e-27 94.5 9.4 4.2e-05 23.7 0.1 6.5 3 3 2 5 5 5 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KEP60108.1 - 7.1e-15 55.0 0.4 0.0034 17.0 0.0 4.7 2 2 2 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KEP60108.1 - 1.1e-14 54.1 2.5 0.03 14.2 0.0 4.8 3 2 1 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEP60108.1 - 1.5e-13 50.7 1.5 0.12 12.5 0.1 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KEP60108.1 - 1.8e-10 40.7 0.0 1.4 8.9 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 KEP60108.1 - 4.6e-08 32.8 3.3 0.8 9.6 0.0 4.6 4 1 0 4 4 4 3 GLUT4 regulating protein TUG FlgD_ig PF13860.1 KEP60108.1 - 9.4e-06 25.2 4.5 7.3 6.4 0.1 4.4 4 0 0 4 4 4 1 FlgD Ig-like domain USP7_C2 PF14533.1 KEP60108.1 - 1.7e-05 24.3 4.8 0.55 9.6 0.5 3.9 1 1 2 3 3 3 3 Ubiquitin-specific protease C-terminal CTDII PF01556.13 KEP60108.1 - 0.0075 16.1 10.2 4.3 7.2 0.0 4.6 3 1 1 4 4 4 1 DnaJ C terminal domain FERM_N PF09379.5 KEP60108.1 - 0.0078 16.2 7.4 42 4.2 0.1 5.6 4 3 0 4 4 4 0 FERM N-terminal domain Plexin_cytopl PF08337.7 KEP60108.1 - 0.0092 14.3 9.8 4.9 5.3 0.0 5.4 5 2 0 5 5 5 1 Plexin cytoplasmic RasGAP domain EMG1 PF03587.9 KEP60108.1 - 0.014 14.7 1.3 17 4.6 0.0 3.7 4 0 0 4 4 4 0 EMG1/NEP1 methyltransferase CpeT PF06206.6 KEP60108.1 - 0.029 14.0 0.1 63 3.1 0.0 3.8 2 1 0 4 4 4 0 CpeT/CpcT family (DUF1001) YfmQ PF10787.4 KEP60108.1 - 0.032 13.6 0.9 50 3.2 0.0 3.7 4 0 0 4 4 4 0 Uncharacterised protein from bacillus cereus group Reo_sigma1 PF01664.11 KEP60108.1 - 0.055 12.5 0.0 6.8 5.6 0.0 3.4 4 0 0 4 4 4 0 Reovirus viral attachment protein sigma 1 GABP-alpha PF11620.3 KEP60108.1 - 0.24 11.4 8.5 37 4.3 0.1 4.0 2 2 2 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 KEP60108.1 - 0.31 11.0 6.7 16 5.5 0.2 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) TMF_DNA_bd PF12329.3 KEP60108.1 - 2.3 8.0 9.2 0.18 11.5 0.6 3.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding HMG_box PF00505.14 KEP60109.1 - 2.7e-20 72.3 3.9 4.6e-20 71.6 2.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEP60109.1 - 5.7e-16 58.6 3.6 9.5e-16 57.9 2.5 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KEP60109.1 - 0.009 15.7 3.3 0.009 15.7 2.3 1.7 1 1 1 2 2 2 1 HMG (high mobility group) box 5 EppA_BapA PF07268.6 KEP60109.1 - 0.044 13.4 0.3 0.053 13.2 0.2 1.2 1 1 0 1 1 1 0 Exported protein precursor (EppA/BapA) KRAB PF01352.22 KEP60109.1 - 0.047 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 KRAB box CKS PF01111.14 KEP60110.1 - 6.7e-17 61.0 0.2 1.5e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_S10 PF00338.17 KEP60110.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ProRS-C_1 PF09180.6 KEP60111.1 - 9.1e-27 92.7 0.1 2.2e-26 91.5 0.1 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KEP60111.1 - 5.4e-21 74.9 0.3 1.1e-20 73.8 0.2 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEP60111.1 - 1.5e-20 72.9 0.0 6.3e-20 70.9 0.0 2.1 3 0 0 3 3 3 1 Anticodon binding domain tRNA_edit PF04073.10 KEP60111.1 - 3e-18 65.8 0.4 5.5e-18 64.9 0.2 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain MCM PF00493.18 KEP60112.1 - 1.2e-133 445.0 0.0 1.7e-133 444.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEP60112.1 - 1.5e-09 38.3 0.1 4.8e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEP60112.1 - 1.4e-05 24.3 0.0 4.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEP60112.1 - 0.012 15.1 0.0 0.04 13.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KEP60112.1 - 0.028 14.8 0.6 0.24 11.8 0.2 2.8 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KEP60112.1 - 0.12 12.2 0.9 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Kinase-like PF14531.1 KEP60113.1 - 2.6e-77 259.6 0.0 3.4e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP60113.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Kinase-like PF14531.1 KEP60114.1 - 9.3e-70 234.8 0.0 3.6e-67 226.3 0.0 2.3 1 1 1 2 2 2 2 Kinase-like DUF1604 PF07713.8 KEP60115.1 - 1.5e-08 34.3 0.1 1.5e-08 34.3 0.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) Fungal_trans_2 PF11951.3 KEP60115.1 - 0.046 12.3 1.1 0.13 10.8 0.7 1.7 1 0 0 1 1 1 0 Fungal specific transcription factor domain Afi1 PF07792.7 KEP60115.1 - 9.4 6.2 8.9 66 3.4 6.1 2.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FCH PF00611.18 KEP60116.1 - 0.0011 19.1 0.5 0.0046 17.1 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Cpl-7 PF08230.6 KEP60116.1 - 0.098 12.3 1.1 7.5 6.3 0.0 2.9 2 0 0 2 2 2 0 Cpl-7 lysozyme C-terminal domain SAG PF04092.8 KEP60117.1 - 1.1e-11 45.2 0.5 2.1e-10 41.0 0.0 2.4 3 0 0 3 3 3 1 SRS domain Phosducin PF02114.11 KEP60118.1 - 9.1e-08 31.1 0.1 1e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KEP60118.1 - 8.4e-07 28.6 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF4224 PF13986.1 KEP60118.1 - 0.014 14.9 2.8 0.035 13.6 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) DUF4254 PF14063.1 KEP60118.1 - 0.027 14.0 2.4 0.048 13.2 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4254) DNA_ligase_A_C PF04679.10 KEP60118.1 - 0.044 14.1 0.4 2.1 8.8 0.3 2.4 1 1 0 1 1 1 0 ATP dependent DNA ligase C terminal region APC_CDC26 PF10471.4 KEP60118.1 - 1.8 9.3 8.8 0.1 13.3 1.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 CENP-X PF09415.5 KEP60118.1 - 2.9 7.7 7.1 92 2.9 3.7 3.1 2 1 0 2 2 2 0 CENP-S associating Centromere protein X zf-ZPR1 PF03367.8 KEP60119.1 - 2.8e-86 286.6 0.0 1.9e-48 163.6 0.0 2.6 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn-ribbon_8 PF09723.5 KEP60119.1 - 0.13 12.2 4.9 27 4.8 0.0 4.3 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KEP60119.1 - 1.1 9.1 10.8 42 4.0 0.0 4.0 3 1 1 4 4 4 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 KEP60119.1 - 1.3 9.0 7.9 28 4.8 0.1 3.8 4 0 0 4 4 4 0 zinc-finger zinc_ribbon_2 PF13240.1 KEP60119.1 - 2.8 7.5 15.1 1.3 8.6 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-Di19 PF05605.7 KEP60119.1 - 8.4 6.6 7.4 16 5.6 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RAP PF08373.5 KEP60120.1 - 0.00099 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 RAP domain SAG PF04092.8 KEP60121.1 - 7.3e-36 123.2 0.0 1.2e-25 90.3 0.0 2.1 2 0 0 2 2 2 2 SRS domain RNA_pol_Rpb1_5 PF04998.12 KEP60122.1 - 0.0024 17.1 1.5 0.0068 15.6 1.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Gpi16 PF04113.9 KEP60123.1 - 7.3e-46 156.3 0.0 3.2e-23 81.5 0.0 3.7 3 1 0 3 3 3 3 Gpi16 subunit, GPI transamidase component Arrestin_N PF00339.24 KEP60124.1 - 9e-16 58.0 0.5 2.9e-14 53.1 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KEP60124.1 - 2.7e-11 43.7 0.0 2.6e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DUF11 PF01345.13 KEP60124.1 - 0.012 15.5 1.3 0.043 13.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF11 Rgp1 PF08737.5 KEP60124.1 - 0.073 12.1 0.3 4.7 6.1 0.0 2.6 2 1 0 2 2 2 0 Rgp1 GTP_EFTU PF00009.22 KEP60125.1 - 8.1e-48 162.3 0.0 1.3e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KEP60125.1 - 2.9e-38 130.0 0.5 5.6e-38 129.1 0.4 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KEP60125.1 - 1.8e-10 40.5 0.0 3.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KEP60125.1 - 0.00079 19.2 0.0 0.0038 17.0 0.0 2.2 1 1 1 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KEP60125.1 - 0.0015 18.5 0.1 0.0042 17.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KEP60125.1 - 0.0028 17.1 0.0 0.0076 15.7 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 KEP60125.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Ras family zf-C3HC4_3 PF13920.1 KEP60126.1 - 2.2e-05 24.0 8.2 2.2e-05 24.0 5.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 KEP60126.1 - 0.007 16.6 0.0 0.042 14.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEP60126.1 - 0.03 14.5 1.0 0.17 12.2 0.1 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP60126.1 - 0.41 11.0 0.3 2.2 8.7 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeat zf-C3HC4_2 PF13923.1 KEP60126.1 - 1.8 8.6 12.9 0.22 11.5 5.2 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RR_TM4-6 PF06459.7 KEP60126.1 - 4.1 7.2 5.0 14 5.4 3.5 1.9 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 6PGD PF00393.14 KEP60127.1 - 5.1e-101 337.7 0.0 9.7e-101 336.8 0.0 1.5 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KEP60127.1 - 1.3e-42 145.4 0.0 1.8e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KEP60127.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SF-assemblin PF06705.6 KEP60128.1 - 7.3e-34 117.0 18.5 1.5e-24 86.4 6.5 2.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin FliS PF02561.9 KEP60128.1 - 0.029 14.2 1.3 0.033 14.0 0.1 1.7 2 0 0 2 2 2 0 Flagellar protein FliS PTS_IIA PF02255.11 KEP60128.1 - 0.078 12.8 1.5 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF1664 PF07889.7 KEP60128.1 - 0.18 11.5 4.4 0.26 11.1 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SPX PF03105.14 KEP60128.1 - 1.6 8.4 7.7 1.5 8.5 4.5 1.4 1 1 0 1 1 1 0 SPX domain Sds3 PF08598.6 KEP60128.1 - 2.1 7.7 8.7 0.78 9.2 2.8 2.1 1 1 1 2 2 2 0 Sds3-like Psb28 PF03912.9 KEP60129.1 - 0.12 12.3 0.2 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Psb28 protein DUF912 PF06024.7 KEP60130.1 - 0.041 13.9 1.4 0.097 12.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Amnionless PF14828.1 KEP60130.1 - 0.15 10.4 3.8 0.033 12.6 0.3 1.6 2 0 0 2 2 2 0 Amnionless PorB PF11565.3 KEP60130.1 - 0.69 10.1 7.4 14 5.9 1.6 3.4 1 1 1 2 2 2 0 Alpha helical Porin B HCV_NS4a PF01006.15 KEP60130.1 - 1.3 8.6 5.2 2.4 7.7 3.6 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a GDA1_CD39 PF01150.12 KEP60132.1 - 9.7e-66 222.0 0.0 3.2e-45 154.4 0.0 2.7 3 0 0 3 3 3 2 GDA1/CD39 (nucleoside phosphatase) family TH1 PF04858.8 KEP60133.1 - 0.028 12.6 0.5 0.046 11.8 0.4 1.2 1 0 0 1 1 1 0 TH1 protein CsgE PF10627.4 KEP60133.1 - 0.092 12.5 2.3 0.53 10.1 0.0 3.0 3 0 0 3 3 3 0 Curli assembly protein CsgE Peptidase_C2 PF00648.16 KEP60134.1 - 0.0048 15.9 0.0 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease Fumble PF03630.9 KEP60135.1 - 6.7e-70 235.6 0.0 4.5e-65 219.7 0.0 2.1 2 0 0 2 2 2 2 Fumble TTL PF03133.10 KEP60136.1 - 5.4e-53 179.8 0.0 1.3e-49 168.7 0.1 2.4 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEP60136.1 - 3.5e-06 25.9 0.1 0.0009 18.1 0.0 2.9 2 1 1 3 3 3 2 YheC/D like ATP-grasp DUF4573 PF15140.1 KEP60137.1 - 0.0014 18.2 1.2 0.15 11.6 0.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4573) RsmJ PF04378.8 KEP60137.1 - 0.022 13.7 2.6 12 4.7 0.0 4.6 1 1 3 5 5 5 0 Ribosomal RNA small subunit methyltransferase D, RsmJ Glu_syn_central PF04898.9 KEP60137.1 - 0.073 12.3 7.6 2.4 7.3 0.0 4.6 1 1 5 6 6 6 0 Glutamate synthase central domain UN_NPL4 PF11543.3 KEP60137.1 - 0.23 11.7 16.1 3.2 8.0 0.2 5.6 2 2 3 5 5 5 0 Nuclear pore localisation protein NPL4 MRP-S32 PF10210.4 KEP60138.1 - 0.045 14.0 4.7 12 6.3 0.0 3.5 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S32 RINGv PF12906.2 KEP60140.1 - 6.4e-12 45.3 5.6 1.1e-11 44.5 3.9 1.5 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.21 KEP60140.1 - 4.5e-11 42.6 0.0 1.4e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 FHA domain Opy2 PF09463.5 KEP60141.1 - 3.4 7.8 3.7 7.2 6.7 2.6 1.5 1 0 0 1 1 1 0 Opy2 protein Clathrin PF00637.15 KEP60146.1 - 8.5e-13 48.1 5.8 1.1 8.8 0.1 7.9 6 1 3 9 9 9 5 Region in Clathrin and VPS WD40 PF00400.27 KEP60146.1 - 5e-06 26.1 3.2 0.61 10.0 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat TPR_7 PF13176.1 KEP60146.1 - 2e-05 24.0 15.2 0.22 11.3 0.0 8.8 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP60146.1 - 3.4e-05 23.2 11.6 0.019 14.7 0.0 7.7 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP60146.1 - 0.00018 21.8 35.3 2.3 9.0 0.0 12.4 10 2 1 12 12 9 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP60146.1 - 0.0009 18.9 18.9 0.83 9.7 0.0 9.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEP60146.1 - 0.004 16.7 18.7 1.6 8.3 0.0 8.7 9 1 1 10 10 9 1 TPR repeat Coatomer_WDAD PF04053.9 KEP60146.1 - 0.014 14.2 5.0 2.6 6.7 0.1 4.2 4 0 0 4 4 4 0 Coatomer WD associated region TPR_1 PF00515.23 KEP60146.1 - 0.25 11.0 14.2 5.1 6.8 0.0 7.2 8 1 1 9 9 9 0 Tetratricopeptide repeat Sec16_C PF12931.2 KEP60146.1 - 0.28 10.8 12.2 1.4 8.6 0.6 5.3 4 1 1 5 5 5 0 Sec23-binding domain of Sec16 Nic96 PF04097.9 KEP60146.1 - 0.37 8.8 5.6 0.49 8.4 1.0 3.2 3 1 0 4 4 4 0 Nup93/Nic96 PUL PF08324.6 KEP60150.1 - 4.7e-30 104.2 0.0 7.5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KEP60150.1 - 6.4e-28 97.0 0.0 1.2e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KEP60150.1 - 1.6e-26 91.1 22.1 4e-07 29.6 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEP60150.1 - 0.022 12.9 8.6 0.11 10.6 2.2 2.8 1 1 0 2 2 2 0 Nucleoporin Nup120/160 CAP PF00188.21 KEP60151.1 - 0.00094 19.6 0.2 0.0016 18.8 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PIN_4 PF13638.1 KEP60151.1 - 0.031 14.3 0.1 0.031 14.3 0.1 2.0 2 0 0 2 2 2 0 PIN domain CobT PF06213.7 KEP60151.1 - 0.044 12.9 12.2 0.063 12.4 8.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT U79_P34 PF03064.11 KEP60151.1 - 0.53 9.7 11.6 0.77 9.2 8.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NPR3 PF03666.8 KEP60151.1 - 1.3 7.4 9.4 1.9 6.9 6.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1510 PF07423.6 KEP60151.1 - 1.3 8.3 14.1 2 7.7 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KEP60151.1 - 1.3 6.5 3.1 1.6 6.3 2.1 1.0 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 KEP60151.1 - 1.4 6.7 18.1 1.8 6.4 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KEP60151.1 - 2.1 6.3 13.2 2.7 5.9 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 KEP60151.1 - 5 4.8 8.2 7.3 4.3 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Stk19 PF10494.4 KEP60152.1 - 8.9e-09 35.1 0.1 2.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Serine-threonine protein kinase 19 DUF3311 PF11755.3 KEP60152.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) GRIP PF01465.15 KEP60153.1 - 1.9e-08 33.6 0.4 5e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 GRIP domain DUF948 PF06103.6 KEP60153.1 - 2.1 8.2 4.7 12 5.8 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TOM_sub5 PF15178.1 KEP60154.1 - 0.0043 16.7 0.1 0.0052 16.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit TOM5 homolog Arf PF00025.16 KEP60156.1 - 2.4e-22 79.0 0.0 2e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 KEP60156.1 - 0.00052 19.2 0.0 0.048 12.8 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Miro PF08477.8 KEP60156.1 - 0.00091 19.7 0.0 2 8.9 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 KEP60156.1 - 0.18 11.2 0.0 5.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Ras family AAA_14 PF13173.1 KEP60156.1 - 0.22 11.4 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Metallothio_Euk PF12749.2 KEP60157.1 - 0.21 11.6 4.5 0.28 11.2 3.1 1.1 1 0 0 1 1 1 0 Eukaryotic metallothionein NHase_alpha PF02979.11 KEP60157.1 - 0.26 10.5 3.9 0.31 10.2 2.7 1.2 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain PspC PF04024.7 KEP60157.1 - 7.6 6.0 10.3 0.73 9.3 2.5 2.3 1 1 0 2 2 2 0 PspC domain DUF4602 PF15375.1 KEP60158.1 - 1.1e-08 35.2 8.4 1.1e-08 35.2 5.8 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4602) Menin PF05053.8 KEP60158.1 - 0.25 9.4 6.9 0.45 8.6 4.8 1.3 1 0 0 1 1 1 0 Menin EMG1 PF03587.9 KEP60160.1 - 1.7e-22 79.6 0.0 1.1e-06 28.1 0.0 4.4 4 1 0 4 4 4 4 EMG1/NEP1 methyltransferase ADK PF00406.17 KEP60162.1 - 5.4e-41 139.9 0.0 6.7e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KEP60162.1 - 1.7e-09 38.5 0.0 2.5e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.9 KEP60162.1 - 0.00022 20.7 1.1 0.00022 20.7 0.7 2.1 2 1 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KEP60162.1 - 0.0016 18.7 0.0 0.0037 17.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEP60162.1 - 0.0029 17.4 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KEP60162.1 - 0.041 14.0 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Staphylokinase PF02821.11 KEP60162.1 - 0.12 12.1 0.1 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family AAA_28 PF13521.1 KEP60162.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SET PF00856.23 KEP60163.1 - 2.8e-05 24.5 1.3 0.00026 21.3 0.0 3.0 3 1 0 3 3 3 1 SET domain HypA PF01155.14 KEP60163.1 - 0.002 17.8 0.2 0.0063 16.1 0.1 1.9 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DNA_RNApol_7kD PF03604.8 KEP60163.1 - 0.27 10.7 3.3 1.3 8.5 2.3 2.2 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit UBX PF00789.15 KEP60164.1 - 2.1e-11 43.6 0.0 7.3e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 UBX domain Asp-B-Hydro_N PF05279.6 KEP60164.1 - 4.8 6.9 12.5 7.5 6.3 8.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SynMuv_product PF06047.6 KEP60165.1 - 2.7e-50 168.4 2.3 2.7e-50 168.4 1.6 4.8 4 0 0 4 4 4 1 Ras-induced vulval development antagonist tRNA-synt_1b PF00579.20 KEP60166.1 - 9.1e-17 61.1 0.0 5.9e-16 58.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HSP90 PF00183.13 KEP60168.1 - 2e-260 864.7 37.9 2.3e-260 864.5 26.3 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 KEP60168.1 - 9.8e-13 47.9 0.2 3.3e-12 46.2 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEP60168.1 - 1.7e-11 43.8 0.1 2.9e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 KEP60168.1 - 0.0021 17.8 0.3 0.008 15.9 0.2 2.0 1 0 0 1 1 1 1 Tumour suppressor protein GAGA_bind PF06217.7 KEP60168.1 - 0.76 9.6 13.3 0.057 13.3 4.4 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Glycos_transf_2 PF00535.21 KEP60169.1 - 4.9e-18 65.3 0.0 3.3e-11 43.1 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 KEP60169.1 - 4.9e-06 25.8 0.0 8.4e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KEP60169.1 - 3.1e-05 23.8 0.2 0.002 17.9 0.0 2.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 U79_P34 PF03064.11 KEP60169.1 - 0.11 11.9 8.6 0.19 11.1 6.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MIP-T3 PF10243.4 KEP60169.1 - 0.38 9.1 12.2 0.69 8.3 8.5 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 KEP60169.1 - 6.2 6.1 9.9 10 5.4 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LETM1 PF07766.8 KEP60170.1 - 1.3e-60 204.7 7.0 2.8e-60 203.6 4.8 1.6 1 0 0 1 1 1 1 LETM1-like protein Pkinase PF00069.20 KEP60172.1 - 9.9e-48 162.5 0.0 3.9e-47 160.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60172.1 - 2.3e-27 95.6 0.0 4.4e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Response_reg PF00072.19 KEP60172.1 - 4.3e-07 29.9 0.0 9.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KEP60172.1 - 0.37 9.6 0.0 0.65 8.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YukC PF10140.4 KEP60172.1 - 0.51 8.8 0.0 0.78 8.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Aldedh PF00171.17 KEP60173.1 - 2e-38 131.9 0.0 2.8e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PTR PF12789.2 KEP60174.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Phage tail repeat like Xpo1 PF08389.7 KEP60175.1 - 0.00073 19.4 0.8 0.0084 16.0 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein DAO PF01266.19 KEP60177.1 - 5.3e-21 74.9 0.0 7.2e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 KEP60177.1 - 1.7e-19 69.4 0.0 3.3e-19 68.4 0.0 1.4 1 1 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 KEP60177.1 - 0.023 14.4 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEP60177.1 - 0.029 14.4 0.0 4.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEP60177.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UCH PF00443.24 KEP60178.1 - 4.8e-16 58.6 0.0 6.7e-13 48.3 0.0 3.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP60178.1 - 0.00013 21.4 0.0 0.00035 20.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.24 KEP60179.1 - 2.6e-31 108.5 0.0 6e-31 107.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP60179.1 - 1e-06 28.8 0.0 3.5e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP60179.1 - 6.3e-06 26.2 0.2 1.7e-05 24.8 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEP60179.1 - 6.7e-06 26.9 0.0 1.4e-05 25.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEP60179.1 - 6e-05 23.3 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEP60179.1 - 0.00011 22.1 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP60179.1 - 0.00016 21.5 0.0 0.0003 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP60179.1 - 0.00033 20.3 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KEP60179.1 - 0.0016 18.1 0.1 0.12 12.0 0.1 2.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 KEP60179.1 - 0.0022 17.7 0.0 0.0047 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KEP60179.1 - 0.0029 17.7 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 KEP60179.1 - 0.0034 17.0 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 KEP60179.1 - 0.0039 16.2 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KEP60179.1 - 0.0044 16.7 0.1 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.12 KEP60179.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein KAP_NTPase PF07693.9 KEP60179.1 - 0.0066 15.4 0.1 0.33 9.8 0.1 2.4 1 1 1 2 2 2 1 KAP family P-loop domain AAA_11 PF13086.1 KEP60179.1 - 0.0074 15.8 0.0 0.019 14.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEP60179.1 - 0.0075 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KEP60179.1 - 0.0081 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.9 KEP60179.1 - 0.0091 15.9 0.0 0.021 14.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 KEP60179.1 - 0.017 14.7 0.0 0.044 13.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 KEP60179.1 - 0.018 14.4 0.0 0.057 12.8 0.0 1.7 1 1 0 2 2 2 0 AAA domain TIP49 PF06068.8 KEP60179.1 - 0.032 12.9 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 KEP60179.1 - 0.034 13.1 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KEP60179.1 - 0.04 13.0 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 KEP60179.1 - 0.048 12.3 0.0 0.085 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 KEP60179.1 - 0.048 12.7 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 KEP60179.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 KEP60179.1 - 0.089 12.6 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 1 0 Shikimate kinase AAA_3 PF07726.6 KEP60179.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEP60179.1 - 0.12 11.6 0.0 0.47 9.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 KEP60179.1 - 0.12 11.2 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 KEP60179.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 KEP60179.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 KEP60179.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Nol1_Nop2_Fmu PF01189.12 KEP60180.1 - 9.8e-86 287.6 0.0 1.4e-85 287.0 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family PCMT PF01135.14 KEP60180.1 - 0.009 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 KEP60180.1 - 0.027 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Nucleoside_tran PF01733.13 KEP60181.1 - 1.1e-20 73.9 10.6 9.5e-13 47.9 6.5 2.4 2 0 0 2 2 2 2 Nucleoside transporter Lustrin_cystein PF14625.1 KEP60181.1 - 6.8 6.8 6.9 0.59 10.2 0.9 2.1 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain DUF106 PF01956.11 KEP60181.1 - 8.2 5.9 7.5 23 4.4 0.3 2.9 1 1 1 2 2 2 0 Integral membrane protein DUF106 Ank_2 PF12796.2 KEP60182.1 - 0.15 12.3 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Plasmodium_Vir PF05795.6 KEP60182.1 - 0.26 10.4 1.5 0.62 9.2 1.0 1.8 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF724 PF05266.9 KEP60185.1 - 0.045 13.3 5.6 0.077 12.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Methyltransf_18 PF12847.2 KEP60186.1 - 3.4e-11 43.7 0.0 5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP60186.1 - 3.8e-10 39.5 0.0 4.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP60186.1 - 4.7e-08 33.0 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP60186.1 - 5.7e-06 26.6 0.0 9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEP60186.1 - 9.3e-06 24.9 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 KEP60186.1 - 1.8e-05 24.4 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 KEP60186.1 - 2.2e-05 23.8 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KEP60186.1 - 2.9e-05 24.4 0.0 4.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KEP60186.1 - 5e-05 22.7 0.0 7.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.15 KEP60186.1 - 6.9e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KEP60186.1 - 0.00017 22.0 0.0 0.00037 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KEP60186.1 - 0.00027 20.0 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 KEP60186.1 - 0.0015 18.3 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KEP60186.1 - 0.0024 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.14 KEP60186.1 - 0.0064 16.0 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KEP60186.1 - 0.0073 15.6 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 KEP60186.1 - 0.0088 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 KEP60186.1 - 0.022 14.4 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KEP60186.1 - 0.097 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Pilt PF15453.1 KEP60187.1 - 0.43 10.2 7.8 0.58 9.7 5.4 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions WD40 PF00400.27 KEP60188.1 - 1.5e-05 24.6 7.9 0.029 14.2 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Ribosomal_L21p PF00829.16 KEP60189.1 - 2e-16 59.8 0.0 3.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Evr1_Alr PF04777.8 KEP60190.1 - 2.1e-20 72.3 1.8 3e-20 71.8 1.2 1.2 1 0 0 1 1 1 1 Erv1 / Alr family NAP PF00956.13 KEP60191.1 - 2.6e-37 128.2 0.5 2.6e-37 128.2 0.4 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Lge1 PF11488.3 KEP60191.1 - 0.016 15.3 0.4 0.038 14.1 0.3 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Radical_SAM PF04055.16 KEP60192.1 - 2.9e-12 47.0 0.5 3.8e-07 30.4 0.0 2.7 2 1 0 2 2 2 2 Radical SAM superfamily RINT1_TIP1 PF04437.8 KEP60194.1 - 0.22 10.0 0.0 0.36 9.3 0.0 1.2 1 0 0 1 1 1 0 RINT-1 / TIP-1 family AP_endonuc_2 PF01261.19 KEP60195.1 - 2.2e-31 108.8 0.0 3e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF3439 PF11921.3 KEP60195.1 - 0.37 10.5 6.3 0.096 12.4 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HSCB_C PF07743.8 KEP60196.1 - 4.3e-08 33.4 2.9 9.3e-08 32.4 2.0 1.6 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KEP60196.1 - 6.4e-06 25.8 2.5 8.9e-06 25.3 1.2 1.7 2 0 0 2 2 2 1 DnaJ domain zf-ribbon_3 PF13248.1 KEP60196.1 - 0.019 14.1 1.9 0.035 13.3 1.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 KEP60196.1 - 0.02 14.6 0.7 0.039 13.7 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF3294 PF07957.6 KEP60196.1 - 0.043 13.3 0.2 0.081 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DMPK_coil PF08826.5 KEP60196.1 - 0.068 13.0 0.2 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 DMPK coiled coil domain like KNOX2 PF03791.8 KEP60196.1 - 0.076 12.3 1.2 1.4 8.2 0.3 2.4 2 0 0 2 2 2 0 KNOX2 domain DUF1272 PF06906.6 KEP60196.1 - 0.13 12.1 0.3 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) NOB1_Zn_bind PF08772.6 KEP60196.1 - 0.14 11.9 0.7 0.29 11.0 0.5 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Snapin_Pallidin PF14712.1 KEP60196.1 - 0.15 12.3 2.5 0.86 9.9 0.2 2.5 2 1 0 2 2 2 0 Snapin/Pallidin zinc_ribbon_2 PF13240.1 KEP60196.1 - 0.18 11.3 2.4 0.32 10.5 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain SMC_N PF02463.14 KEP60197.1 - 1.2e-43 148.9 0.0 4.9e-41 140.3 0.0 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEP60197.1 - 3.2e-28 98.1 0.0 5.1e-27 94.2 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEP60197.1 - 3e-11 43.8 0.0 0.00026 21.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEP60197.1 - 0.00014 21.3 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KEP60197.1 - 0.02 15.0 3.5 0.12 12.5 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) PDGLE PF13190.1 KEP60197.1 - 0.1 12.3 0.3 0.97 9.1 0.1 2.7 2 0 0 2 2 2 0 PDGLE domain ABC_tran PF00005.22 KEP60197.1 - 0.12 12.6 0.0 0.12 12.6 0.0 5.4 4 1 0 5 5 5 0 ABC transporter AAA_17 PF13207.1 KEP60197.1 - 0.66 10.8 0.0 0.66 10.8 0.0 4.3 4 1 0 4 4 4 0 AAA domain Ribosomal_L16 PF00252.13 KEP60199.1 - 1.5e-31 108.9 0.0 2e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol_B_thumb PF14791.1 KEP60200.1 - 4.3e-18 64.7 0.1 1.5e-08 34.2 0.0 2.8 2 0 0 2 2 2 2 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KEP60200.1 - 3e-16 59.4 0.0 5e-13 49.0 0.0 3.4 2 1 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KEP60200.1 - 9.9e-07 28.2 0.0 0.00024 20.5 0.0 2.4 2 0 0 2 2 2 2 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 KEP60200.1 - 0.00045 20.3 0.0 0.0015 18.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_8 PF14716.1 KEP60200.1 - 0.0018 18.3 0.2 2.1 8.6 0.0 3.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain Asparaginase PF00710.15 KEP60201.1 - 5.1e-86 288.3 0.0 7.3e-86 287.8 0.0 1.1 1 0 0 1 1 1 1 Asparaginase UCR_14kD PF02271.11 KEP60202.1 - 1.2e-12 47.4 0.1 2.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Exo_endo_phos PF03372.18 KEP60203.1 - 1.1e-10 41.8 0.1 2.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mg_trans_NIPA PF05653.9 KEP60204.1 - 1.3e-28 99.8 11.8 2.1e-28 99.1 8.2 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KEP60204.1 - 3.2e-09 36.9 21.0 0.00016 21.6 4.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KEP60204.1 - 0.00012 22.2 7.0 0.00012 22.2 4.9 2.8 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Pyr_redox_2 PF07992.9 KEP60205.1 - 3.8e-23 82.4 0.0 5.6e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEP60205.1 - 1.4e-09 38.1 0.0 2.7e-08 34.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEP60205.1 - 0.02 14.9 0.0 1.4 8.9 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPPK_C PF12555.3 KEP60206.1 - 0.0015 18.2 0.4 0.0035 17.0 0.3 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal COPI_assoc PF08507.5 KEP60207.1 - 0.2 11.3 1.8 0.24 11.0 1.3 1.1 1 0 0 1 1 1 0 COPI associated protein PGPGW PF09656.5 KEP60207.1 - 5.4 6.3 9.9 3.2 7.1 2.5 2.3 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) DUF3096 PF11295.3 KEP60207.1 - 8.5 5.9 7.2 0.44 10.0 0.7 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) TIP49 PF06068.8 KEP60208.1 - 5.1e-177 588.5 0.8 6e-177 588.2 0.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KEP60208.1 - 2.3e-12 47.2 0.8 4e-08 33.5 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP60208.1 - 2.8e-08 33.9 0.2 8.6e-07 29.1 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KEP60208.1 - 3.4e-08 32.8 1.8 2.3e-05 23.5 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEP60208.1 - 1e-07 32.1 0.1 0.008 16.3 0.1 2.6 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KEP60208.1 - 2.6e-06 26.6 0.0 7.7e-06 25.1 0.0 1.8 2 0 0 2 2 1 1 Zeta toxin DnaB_C PF03796.10 KEP60208.1 - 6.4e-06 25.2 0.1 1.2e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 KEP60208.1 - 1.3e-05 24.9 0.4 0.017 14.8 0.0 3.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEP60208.1 - 4.3e-05 22.7 0.6 0.0026 16.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KEP60208.1 - 7.8e-05 23.4 0.0 0.0002 22.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEP60208.1 - 0.00041 19.8 0.0 0.0019 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEP60208.1 - 0.00042 20.0 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 KEP60208.1 - 0.00053 20.2 0.0 0.0023 18.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 KEP60208.1 - 0.00079 18.9 0.1 0.75 9.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 KEP60208.1 - 0.0021 17.5 0.1 0.075 12.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KEP60208.1 - 0.0023 17.6 0.1 0.0074 16.0 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 KEP60208.1 - 0.0033 17.2 0.2 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEP60208.1 - 0.0038 17.1 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 KEP60208.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 KEP60208.1 - 0.013 14.5 0.1 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 KEP60208.1 - 0.017 14.2 1.2 0.039 13.0 0.0 2.2 3 0 0 3 3 2 0 KaiC APS_kinase PF01583.15 KEP60208.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Zot PF05707.7 KEP60208.1 - 0.03 13.7 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 KEP60208.1 - 0.042 13.4 0.1 0.097 12.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 KEP60208.1 - 0.048 13.2 0.1 0.2 11.2 0.0 2.0 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.1 KEP60208.1 - 0.097 12.2 0.1 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 KEP60208.1 - 0.11 12.6 0.0 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 KEP60208.1 - 0.12 11.8 0.4 0.3 10.5 0.1 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 KEP60208.1 - 0.17 12.0 0.0 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ALF PF03752.8 KEP60209.1 - 0.0009 19.0 0.1 0.0009 19.0 0.0 2.3 2 0 0 2 2 2 1 Short repeats of unknown function Spc97_Spc98 PF04130.8 KEP60210.1 - 0.0022 16.4 0.0 0.0044 15.3 0.0 1.7 1 1 0 1 1 1 1 Spc97 / Spc98 family DUF866 PF05907.8 KEP60212.1 - 1.4e-35 122.2 0.0 1.5e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) ABC_tran PF00005.22 KEP60213.1 - 5.9e-21 75.2 0.0 1.1e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 KEP60213.1 - 5.3e-16 58.4 16.6 9.9e-16 57.5 11.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_25 PF13481.1 KEP60213.1 - 2.4e-06 27.1 0.0 0.0071 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEP60213.1 - 9.3e-05 22.4 0.1 0.00029 20.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEP60213.1 - 0.00026 21.1 0.1 0.00079 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEP60213.1 - 0.00058 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 KEP60213.1 - 0.00069 19.3 0.0 0.0025 17.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KEP60213.1 - 0.0013 18.4 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 KEP60213.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 KEP60213.1 - 0.031 15.1 0.0 0.094 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEP60213.1 - 0.033 13.7 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 KEP60213.1 - 0.035 14.3 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEP60213.1 - 0.062 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.1 KEP60213.1 - 0.073 13.0 0.0 0.7 9.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEP60213.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 KEP60213.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 KEP60213.1 - 0.17 10.8 12.3 0.24 10.3 8.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_14 PF13173.1 KEP60213.1 - 0.35 10.7 0.0 0.68 9.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KEP60213.1 - 0.57 8.7 0.0 0.86 8.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Herpes_BLLF1 PF05109.8 KEP60213.1 - 2.9 5.7 5.0 4.2 5.2 3.5 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Cnd2 PF05786.9 KEP60214.1 - 1.6e-25 89.7 12.9 7.5e-19 67.7 0.2 4.3 4 0 0 4 4 4 3 Condensin complex subunit 2 DUF4570 PF15134.1 KEP60218.1 - 0.084 12.7 0.4 0.15 11.9 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) IGR PF09597.5 KEP60219.1 - 0.0014 18.5 0.3 0.0039 17.0 0.0 1.9 2 0 0 2 2 2 1 IGR protein motif HHH_5 PF14520.1 KEP60219.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KEP60219.1 - 0.0086 15.9 0.1 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif Myb_DNA-bind_6 PF13921.1 KEP60219.1 - 0.015 15.4 0.2 0.036 14.1 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain SAM_1 PF00536.25 KEP60219.1 - 0.16 12.1 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RNA_pol_Rpb1_1 PF04997.7 KEP60220.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 CwfJ_C_1 PF04677.10 KEP60221.1 - 1e-25 89.7 0.2 1.8e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.17 KEP60221.1 - 3.4e-11 42.5 0.0 6.3e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60221.1 - 4.7e-07 29.6 0.0 9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.9 KEP60221.1 - 6e-05 23.4 0.0 0.0002 21.8 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 RRM_5 PF13893.1 KEP60221.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bundlin PF05307.6 KEP60222.1 - 0.057 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Bundlin V-ATPase_H_N PF03224.9 KEP60223.1 - 0.0014 17.8 4.7 0.0098 15.0 0.1 3.7 5 1 0 5 5 5 1 V-ATPase subunit H DnaA_N PF11638.3 KEP60223.1 - 0.052 13.1 0.0 0.29 10.7 0.0 2.3 1 0 0 1 1 1 0 DnaA N-terminal domain FAM150 PF15129.1 KEP60223.1 - 0.096 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 FAM150 family DUF2411 PF10304.4 KEP60223.1 - 0.15 11.6 1.7 2.3 7.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2411) HEAT_EZ PF13513.1 KEP60223.1 - 5.7 7.5 7.5 40 4.8 0.0 4.8 4 1 1 5 5 5 0 HEAT-like repeat Arm PF00514.18 KEP60224.1 - 2.6e-10 39.7 1.6 0.31 10.9 0.0 6.3 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEP60224.1 - 7e-07 29.4 1.2 0.069 13.4 0.0 4.2 2 2 2 4 4 4 3 HEAT repeats KAP PF05804.7 KEP60224.1 - 0.0027 15.7 0.0 0.0044 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT PF02985.17 KEP60224.1 - 0.042 13.9 1.4 16 5.8 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Pkinase PF00069.20 KEP60225.1 - 1.5e-12 47.2 0.0 4.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60225.1 - 6e-05 22.2 0.0 0.038 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEP60225.1 - 0.017 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEP60225.1 - 0.15 10.9 0.1 0.75 8.6 0.1 1.9 2 0 0 2 2 2 0 Kinase-like E1-E2_ATPase PF00122.15 KEP60227.1 - 3.1e-19 68.9 0.0 3.3e-18 65.5 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEP60227.1 - 3.1e-15 57.1 0.0 4.6e-05 23.9 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP60227.1 - 6.1e-13 49.3 0.0 6.4e-07 29.7 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP60227.1 - 0.0015 18.4 0.0 0.0049 16.7 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Adaptin_N PF01602.15 KEP60228.1 - 1.1e-73 248.3 0.1 1.7e-42 145.4 1.6 2.2 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 KEP60228.1 - 0.0001 22.1 3.7 0.0016 18.3 1.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEP60228.1 - 0.00069 19.8 1.6 0.00069 19.8 1.1 4.5 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 KEP60228.1 - 0.043 13.9 19.6 0.62 10.2 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat HOOK PF05622.7 KEP60229.1 - 2e-13 49.0 83.7 1.8e-12 45.9 58.0 3.0 1 1 0 1 1 1 1 HOOK protein DUF1643 PF07799.7 KEP60229.1 - 0.08 12.6 4.5 1.9 8.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1643) Reo_sigmaC PF04582.7 KEP60229.1 - 2 7.4 24.3 0.083 12.0 3.3 4.3 1 1 3 5 5 5 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 KEP60229.1 - 7.5 6.4 20.7 10 5.9 0.0 7.0 7 1 1 8 8 8 0 DASH complex subunit Dam1 DUF641 PF04859.7 KEP60231.1 - 0.0052 16.5 9.0 0.012 15.3 6.0 1.8 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) End3 PF12761.2 KEP60231.1 - 1.9 8.0 11.1 4.7 6.8 7.7 1.7 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 V_ATPase_I PF01496.14 KEP60231.1 - 9.8 3.8 3.4 15 3.2 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tim54 PF11711.3 KEP60232.1 - 0.64 8.5 3.0 1.1 7.7 2.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM171 PF15471.1 KEP60232.1 - 6 5.5 9.8 12 4.5 6.8 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 L51_S25_CI-B8 PF05047.11 KEP60233.1 - 0.00035 20.2 0.1 0.00063 19.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF202 PF02656.10 KEP60234.1 - 0.14 12.4 1.2 0.32 11.2 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TAXi_N PF14543.1 KEP60235.1 - 0.029 14.3 0.1 0.032 14.1 0.1 1.1 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Guanylate_cyc PF00211.15 KEP60236.1 - 3.4e-20 72.1 0.0 5.6e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.26 KEP60236.1 - 2.2e-05 23.8 0.2 5.7e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Ion transport protein Thioredoxin_8 PF13905.1 KEP60237.1 - 4.3e-20 71.6 0.0 6.6e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEP60237.1 - 5.6e-08 32.9 0.0 8.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KEP60237.1 - 0.00026 20.6 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.15 KEP60237.1 - 0.0036 16.9 0.1 0.094 12.4 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KEP60237.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like TPR_11 PF13414.1 KEP60238.1 - 4.5e-15 55.0 9.9 5.4e-07 29.1 0.0 4.4 3 1 3 6 6 4 3 TPR repeat TPR_1 PF00515.23 KEP60238.1 - 1.2e-13 49.9 1.9 2.2e-05 23.8 0.3 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP60238.1 - 1.1e-10 40.4 0.0 0.022 14.5 0.1 4.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP60238.1 - 8.3e-10 37.8 19.2 0.0001 21.9 0.8 6.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEP60238.1 - 6e-09 36.3 6.8 6.4e-07 29.8 0.2 6.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP60238.1 - 1.5e-07 31.1 0.7 1.5e-07 31.1 0.5 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP60238.1 - 1.9e-07 30.3 9.5 0.099 12.4 0.1 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEP60238.1 - 2.5e-06 27.3 13.3 0.00037 20.3 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEP60238.1 - 4.1e-05 23.8 5.2 0.083 13.2 0.1 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP60238.1 - 0.00034 20.9 27.3 0.019 15.5 0.4 7.2 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP60238.1 - 0.0014 18.6 0.1 4.9 7.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3662 PF12401.3 KEP60238.1 - 0.041 14.0 0.2 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) TPR_6 PF13174.1 KEP60238.1 - 0.19 12.2 6.0 5.1 7.7 0.0 4.8 5 1 0 5 5 3 0 Tetratricopeptide repeat PPP4R2 PF09184.6 KEP60238.1 - 5 6.5 8.2 11 5.4 5.7 1.5 1 0 0 1 1 1 0 PPP4R2 RAP PF08373.5 KEP60239.1 - 3.4e-10 39.5 0.0 7.2e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 RAP domain ChpXY PF10216.4 KEP60239.1 - 0.075 11.8 0.1 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 CO2 hydration protein (ChpXY) Nucleoplasmin PF03066.10 KEP60239.1 - 0.46 9.9 4.4 0.95 8.9 3.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin Prefoldin_2 PF01920.15 KEP60240.1 - 9.8e-11 41.3 0.6 8.9e-08 31.8 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit SlyX PF04102.7 KEP60240.1 - 0.0035 17.6 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 1 SlyX Tropomyosin_1 PF12718.2 KEP60240.1 - 0.0099 15.7 4.5 0.056 13.2 0.0 2.2 2 0 0 2 2 2 1 Tropomyosin like MAD PF05557.8 KEP60240.1 - 0.01 14.0 2.8 0.039 12.0 0.0 2.0 2 0 0 2 2 2 1 Mitotic checkpoint protein IncA PF04156.9 KEP60240.1 - 0.025 14.1 3.7 0.79 9.2 0.1 2.0 2 0 0 2 2 2 0 IncA protein Prefoldin PF02996.12 KEP60240.1 - 0.037 13.6 2.9 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit Snapin_Pallidin PF14712.1 KEP60240.1 - 0.05 13.9 0.4 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Spc24 PF08286.6 KEP60240.1 - 0.061 13.0 1.9 6.5 6.4 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 MerR-DNA-bind PF09278.6 KEP60240.1 - 0.09 13.1 3.7 3.4 8.1 0.5 2.3 2 0 0 2 2 2 0 MerR, DNA binding DivIC PF04977.10 KEP60240.1 - 0.099 12.1 2.9 2.9 7.4 0.8 2.2 2 0 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.4 KEP60240.1 - 0.13 12.1 5.9 0.52 10.1 1.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HR1 PF02185.11 KEP60240.1 - 0.23 11.2 2.7 6 6.6 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat DUF465 PF04325.8 KEP60240.1 - 0.25 11.1 4.5 0.17 11.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Filament PF00038.16 KEP60240.1 - 0.26 10.7 4.7 1.7 8.0 3.2 1.9 1 1 0 1 1 1 0 Intermediate filament protein PspA_IM30 PF04012.7 KEP60240.1 - 0.34 10.2 4.1 2.7 7.2 0.7 2.6 2 1 0 2 2 2 0 PspA/IM30 family Fzo_mitofusin PF04799.8 KEP60240.1 - 0.35 10.2 1.8 0.61 9.4 0.1 1.8 2 0 0 2 2 2 0 fzo-like conserved region DUF4349 PF14257.1 KEP60240.1 - 0.46 9.6 3.8 0.89 8.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) ATG16 PF08614.6 KEP60240.1 - 0.55 10.0 5.5 1.3 8.7 0.8 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Med9 PF07544.8 KEP60240.1 - 1.2 8.9 3.8 8.1 6.2 0.5 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SR-25 PF10500.4 KEP60241.1 - 0.0028 17.1 8.9 0.0028 17.1 6.2 6.5 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein zf-Di19 PF05605.7 KEP60241.1 - 0.027 14.5 6.9 0.058 13.5 3.8 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L12 PF00542.14 KEP60242.1 - 4.6e-19 68.1 4.9 4.6e-19 68.1 3.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DnaJ PF00226.26 KEP60243.1 - 5.2e-19 67.7 1.1 1e-18 66.7 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain ADH_zinc_N PF00107.21 KEP60243.1 - 7.9e-07 28.6 0.0 0.0014 18.1 0.0 2.7 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 KEP60243.1 - 0.044 13.5 0.0 0.16 11.7 0.0 2.0 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Pro_isomerase PF00160.16 KEP60244.1 - 2.7e-49 167.3 0.0 3.1e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PapD-like PF14874.1 KEP60245.1 - 2.8e-09 36.8 0.0 6.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like tRNA-synt_1g PF09334.6 KEP60247.1 - 3.6e-114 381.4 0.2 6.7e-113 377.2 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEP60247.1 - 4.7e-35 120.6 1.5 6.6e-21 73.9 0.1 3.7 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KEP60247.1 - 2.2e-14 53.3 0.0 2e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA_bind PF01588.15 KEP60247.1 - 8.8e-08 31.8 0.2 4.7e-07 29.5 0.2 2.1 1 1 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1f PF01921.13 KEP60247.1 - 1.1e-05 24.2 0.0 0.0011 17.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1d PF00750.14 KEP60247.1 - 0.023 13.4 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 KEP60247.1 - 0.19 10.8 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Cullin PF00888.17 KEP60248.1 - 8e-136 453.9 0.1 2.7e-72 244.1 0.0 2.2 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 KEP60248.1 - 4.4e-27 93.7 1.9 4.4e-27 93.7 1.3 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain LUC7 PF03194.10 KEP60248.1 - 0.0082 15.7 1.1 0.017 14.6 0.7 1.5 1 0 0 1 1 1 1 LUC7 N_terminus Pkinase PF00069.20 KEP60250.1 - 6.7e-42 143.4 0.0 8.6e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60250.1 - 5.8e-23 81.2 0.0 7.2e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP60250.1 - 1.5e-08 34.6 0.0 0.00026 20.7 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEP60250.1 - 0.024 13.4 0.1 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KEP60250.1 - 0.04 12.9 0.0 0.087 11.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEP60250.1 - 0.058 12.3 0.0 1.1 8.1 0.0 2.6 2 1 0 2 2 2 0 Kinase-like UCH PF00443.24 KEP60251.1 - 1.3e-45 155.6 0.0 1.8e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP60251.1 - 5e-18 65.5 0.0 2.1e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 KEP60251.1 - 2.5e-06 27.0 0.0 5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.3 KEP60251.1 - 0.33 10.1 0.0 12 4.9 0.0 2.5 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C2HC_2 PF13913.1 KEP60252.1 - 0.038 13.6 9.9 0.12 12.0 1.8 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sgf11 PF08209.6 KEP60252.1 - 0.18 11.1 7.3 0.53 9.6 0.2 2.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2 PF00096.21 KEP60252.1 - 6.7 7.2 10.3 5.5 7.5 3.8 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type ABC2_membrane PF01061.19 KEP60253.1 - 7.5e-39 133.0 18.4 1.2e-38 132.4 12.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KEP60253.1 - 7.3e-24 84.6 0.0 1.4e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 KEP60253.1 - 6.6e-15 54.9 12.5 9.7e-15 54.4 8.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 KEP60253.1 - 5.7e-08 33.0 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEP60253.1 - 0.00014 21.0 0.1 0.00026 20.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEP60253.1 - 0.0028 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KEP60253.1 - 0.0031 16.6 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 KEP60253.1 - 0.011 15.7 0.3 0.027 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 KEP60253.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 KEP60253.1 - 0.027 14.4 0.5 0.082 12.8 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_25 PF13481.1 KEP60253.1 - 0.037 13.4 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEP60253.1 - 0.05 14.4 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEP60253.1 - 0.075 13.3 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KEP60253.1 - 0.12 11.6 0.1 1.2 8.2 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain HH_signal PF01085.13 KEP60253.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain DUF4186 PF13811.1 KEP60256.1 - 0.039 13.6 1.0 0.043 13.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) SpoIIE PF07228.7 KEP60258.1 - 8.7e-10 38.6 0.1 0.00043 20.0 0.1 2.5 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEP60258.1 - 0.00081 18.8 2.3 0.0019 17.6 0.1 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C Gar1 PF04410.9 KEP60259.1 - 3.1e-16 59.2 0.0 2.6e-15 56.1 0.0 2.5 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region Vps8 PF12816.2 KEP60260.1 - 0.075 12.2 0.4 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 zf-C3HC4 PF00097.20 KEP60260.1 - 0.24 11.1 1.7 0.72 9.5 1.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L19e PF01280.15 KEP60261.1 - 2.5e-61 205.7 13.5 2.5e-61 205.7 9.3 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e Sec62 PF03839.11 KEP60261.1 - 5.3 6.3 11.3 43 3.4 0.0 2.3 2 1 0 2 2 2 0 Translocation protein Sec62 ADIP PF11559.3 KEP60262.1 - 0.00029 20.7 5.6 0.00029 20.7 3.9 5.4 4 1 2 6 6 6 3 Afadin- and alpha -actinin-Binding Exonuc_VII_S PF02609.11 KEP60262.1 - 2.9 7.7 14.7 0.67 9.7 1.3 4.9 4 1 0 4 4 4 0 Exonuclease VII small subunit Reo_sigmaC PF04582.7 KEP60262.1 - 4.8 6.2 11.4 9.5 5.2 0.0 3.9 2 1 0 3 3 3 0 Reovirus sigma C capsid protein WD40 PF00400.27 KEP60263.1 - 6.7e-20 70.1 10.6 5.2e-08 32.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 KEP60263.1 - 0.00063 18.0 0.3 0.0016 16.7 0.2 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Daxx PF03344.10 KEP60263.1 - 7.6 4.8 16.7 8.7 4.6 8.3 2.0 2 0 0 2 2 2 0 Daxx Family RRM_1 PF00076.17 KEP60264.1 - 1.2e-16 60.0 0.0 1.9e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60264.1 - 4.2e-14 52.2 0.0 6.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP60264.1 - 7.8e-10 38.4 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IP_trans PF02121.13 KEP60265.1 - 1.1e-64 218.0 0.2 4.6e-44 150.4 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol transfer protein Oxysterol_BP PF01237.13 KEP60265.1 - 3.3e-40 137.6 0.0 6.9e-40 136.6 0.0 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 KEP60265.1 - 4e-09 36.6 0.0 1.1e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 KEP60265.1 - 0.00014 22.0 0.2 0.0015 18.7 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Str_synth PF03088.11 KEP60266.1 - 2e-19 69.4 0.0 1e-16 60.7 0.0 2.6 2 0 0 2 2 2 2 Strictosidine synthase SGL PF08450.7 KEP60266.1 - 1.4e-07 31.1 0.0 3.4e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Guanylate_cyc PF00211.15 KEP60267.1 - 0.11 11.8 0.1 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain DinB_2 PF12867.2 KEP60267.1 - 0.12 12.7 4.2 0.72 10.2 0.7 2.4 1 1 1 2 2 2 0 DinB superfamily DRIM PF07539.7 KEP60267.1 - 0.45 9.9 7.1 7.4 5.9 3.7 2.5 2 1 0 2 2 2 0 Down-regulated in metastasis DDE_Tnp_IS66 PF03050.9 KEP60267.1 - 0.51 9.5 8.5 0.14 11.3 3.5 1.6 1 1 1 2 2 2 0 Transposase IS66 family DUF2400 PF09674.5 KEP60267.1 - 0.61 9.7 6.2 0.85 9.2 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) DUF883 PF05957.8 KEP60267.1 - 0.66 10.4 11.5 4.7 7.6 1.1 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.10 KEP60267.1 - 0.7 9.0 7.2 0.77 8.8 5.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HTH_37 PF13744.1 KEP60267.1 - 0.83 9.4 7.5 0.41 10.4 1.9 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain Dict-STAT-coil PF09267.5 KEP60267.1 - 1.1 9.4 6.0 0.48 10.6 1.1 2.1 1 1 0 2 2 2 0 Dictyostelium STAT, coiled coil MutS_IV PF05190.13 KEP60267.1 - 4.5 7.5 9.3 7.4 6.8 0.9 3.3 1 1 2 3 3 3 0 MutS family domain IV Jnk-SapK_ap_N PF09744.4 KEP60267.1 - 5.6 6.9 13.9 9.9 6.1 9.4 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Iron_permease PF04120.7 KEP60267.1 - 6.6 6.3 9.5 4.2 6.9 2.1 2.1 1 1 1 2 2 2 0 Low affinity iron permease HSP20 PF00011.16 KEP60268.1 - 2e-19 69.3 0.0 3.3e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4140 PF13600.1 KEP60268.1 - 0.068 13.6 0.0 32 5.0 0.0 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) GvpH PF05455.6 KEP60268.1 - 0.16 11.5 0.1 0.5 9.9 0.0 1.8 3 0 0 3 3 3 0 GvpH Pox_P21 PF05313.7 KEP60269.1 - 0.27 10.4 1.3 0.41 9.8 0.9 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF2842 PF11003.3 KEP60269.1 - 0.63 9.9 3.3 13 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) Peptidase_C1 PF00112.18 KEP60271.1 - 3.9e-37 128.2 12.7 4.1e-29 102.0 6.7 3.2 2 1 0 2 2 2 2 Papain family cysteine protease CathepsinC_exc PF08773.6 KEP60271.1 - 1.6e-06 28.2 0.0 0.0058 16.7 0.0 2.5 2 0 0 2 2 2 2 Cathepsin C exclusion domain Propeptide_C1 PF08127.8 KEP60271.1 - 0.00036 20.0 0.2 0.00095 18.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.10 KEP60271.1 - 0.0013 17.3 0.7 0.1 11.0 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family GFP PF01353.17 KEP60271.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Green fluorescent protein DcpS_C PF11969.3 KEP60273.1 - 3.6e-06 27.1 0.0 0.00026 21.2 0.0 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding PEPCK_ATP PF01293.15 KEP60274.1 - 1.2e-214 713.1 0.0 1.4e-214 712.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.1 KEP60274.1 - 0.027 13.8 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEP60274.1 - 0.032 13.7 0.1 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KEP60274.1 - 0.05 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DRMBL PF07522.9 KEP60276.1 - 5.3e-22 77.9 0.1 1.1e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KEP60276.1 - 4.8e-13 49.0 0.1 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KEP60276.1 - 0.00036 20.2 0.0 0.00081 19.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KEP60276.1 - 0.0048 16.5 3.7 0.012 15.2 2.6 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TIP49 PF06068.8 KEP60276.1 - 0.016 13.9 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Ras PF00071.17 KEP60277.1 - 2.8e-62 208.8 0.2 3.4e-62 208.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP60277.1 - 8.8e-20 71.3 0.0 1.5e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP60277.1 - 5.6e-14 51.7 0.1 7.2e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEP60277.1 - 1.7e-06 27.9 0.0 9.1e-06 25.6 0.0 2.0 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP60277.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEP60277.1 - 3.7e-05 22.9 0.1 7e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 KEP60277.1 - 0.0017 18.2 0.1 0.0055 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEP60277.1 - 0.0021 18.1 0.1 0.007 16.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 KEP60277.1 - 0.014 14.6 0.1 0.032 13.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KEP60277.1 - 0.023 13.9 0.0 0.051 12.7 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KEP60277.1 - 0.087 13.1 0.5 0.27 11.5 0.3 2.0 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KEP60277.1 - 0.1 12.5 0.7 0.45 10.4 0.4 2.2 1 1 1 2 2 2 0 AAA ATPase domain Gp_dh_C PF02800.15 KEP60278.1 - 1.9e-68 228.8 0.2 2.9e-68 228.2 0.0 1.4 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KEP60278.1 - 2e-60 203.1 0.0 9.1e-60 201.0 0.0 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pep3_Vps18 PF05131.9 KEP60281.1 - 3e-27 94.8 0.0 6.4e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KEP60281.1 - 6.1e-05 22.6 0.0 0.0052 16.3 0.0 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 KEP60281.1 - 0.00014 21.9 3.0 0.00039 20.5 2.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF3782 PF12644.2 KEP60281.1 - 0.00054 19.6 0.9 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3782) zf-RING_2 PF13639.1 KEP60281.1 - 0.0024 17.6 7.7 0.0024 17.6 5.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KEP60281.1 - 0.61 9.8 12.0 0.068 12.9 5.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP60281.1 - 1.9 8.6 15.2 0.77 9.8 7.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rdx PF10262.4 KEP60282.1 - 7.8e-06 25.8 0.0 8.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Rdx family BTB PF00651.26 KEP60283.1 - 0.0056 16.6 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain ubiquitin PF00240.18 KEP60284.1 - 3.4e-35 119.2 0.5 4.5e-35 118.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 KEP60284.1 - 2.6e-32 110.1 11.6 4.2e-32 109.5 8.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 KEP60284.1 - 1.6e-20 72.5 0.5 2.4e-20 71.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEP60284.1 - 2.6e-06 27.5 0.1 9.2e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KEP60284.1 - 0.00038 20.1 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KEP60284.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEP60284.1 - 0.016 15.3 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 KEP60284.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Fer2_3 PF13085.1 KEP60284.1 - 0.24 11.2 2.1 1.2 8.9 1.1 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain BPL_LplA_LipB PF03099.14 KEP60285.1 - 2e-10 40.7 0.0 4.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KEP60285.1 - 0.001 18.7 0.1 0.0024 17.5 0.1 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Adap_comp_sub PF00928.16 KEP60286.1 - 9.9e-85 283.7 0.0 1.2e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEP60286.1 - 8e-07 28.8 0.9 1.5e-06 27.9 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SH3_5 PF08460.5 KEP60286.1 - 0.18 11.7 0.5 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain AAA_2 PF07724.9 KEP60287.1 - 7e-41 139.9 0.3 8e-33 113.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEP60287.1 - 3e-14 53.3 0.1 8.4e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEP60287.1 - 7.7e-09 35.3 0.1 2.3e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 KEP60287.1 - 1.4e-07 32.3 0.1 3.9e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEP60287.1 - 1.6e-07 31.1 0.1 1.9e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEP60287.1 - 1.1e-06 28.8 0.6 2.6e-05 24.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KEP60287.1 - 2.4e-06 27.6 0.1 6.3e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KEP60287.1 - 2.1e-05 24.8 0.0 4.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEP60287.1 - 6.6e-05 22.0 0.2 0.0098 14.9 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus MCM PF00493.18 KEP60287.1 - 0.00046 19.0 0.0 0.0079 15.0 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family Zeta_toxin PF06414.7 KEP60287.1 - 0.00092 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 KEP60287.1 - 0.0015 17.3 0.0 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KEP60287.1 - 0.0028 17.5 0.1 0.0077 16.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 KEP60287.1 - 0.0067 15.9 0.0 0.048 13.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KEP60287.1 - 0.0087 15.9 0.1 0.97 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 KEP60287.1 - 0.021 14.7 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase Mg_chelatase PF01078.16 KEP60287.1 - 0.024 13.8 0.5 0.092 11.8 0.0 2.1 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KEP60287.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 KEP60287.1 - 0.033 14.0 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 KEP60287.1 - 0.052 13.2 0.3 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 NTPase DUF258 PF03193.11 KEP60287.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KEP60287.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KEP60287.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 KEP60287.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Arch_ATPase PF01637.13 KEP60287.1 - 0.12 12.1 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 KEP60287.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase EMP24_GP25L PF01105.19 KEP60290.1 - 1.7e-33 115.8 0.0 2e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RabGAP-TBC PF00566.13 KEP60292.1 - 4.9e-41 140.5 0.2 7e-40 136.7 0.2 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 KEP60293.1 - 2.3e-27 93.8 12.5 1.4e-09 37.4 0.0 5.9 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 KEP60293.1 - 0.00015 21.2 0.0 0.0012 18.3 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain YmzC PF14157.1 KEP60293.1 - 0.03 14.1 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 YmzC-like protein Ricin_B_lectin PF00652.17 KEP60293.1 - 0.23 11.5 2.6 0.64 10.0 0.2 2.5 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain CHCH PF06747.8 KEP60293.1 - 0.81 9.6 3.0 5.1 7.1 0.1 3.2 3 0 0 3 3 3 0 CHCH domain TrbL PF04610.9 KEP60295.1 - 0.0035 17.0 0.0 0.0043 16.7 0.0 1.1 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein FlgM PF04316.8 KEP60295.1 - 0.011 15.6 0.2 0.027 14.4 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF485 PF04341.7 KEP60295.1 - 0.021 14.5 0.0 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Osteopontin PF00865.13 KEP60295.1 - 0.056 12.6 0.7 0.072 12.3 0.5 1.1 1 0 0 1 1 1 0 Osteopontin DUF106 PF01956.11 KEP60295.1 - 0.099 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3357 PF11837.3 KEP60295.1 - 0.43 10.4 2.4 0.8 9.5 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF900 PF05990.7 KEP60297.1 - 9.7e-19 67.6 0.0 1.9e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Acetyltransf_1 PF00583.19 KEP60299.1 - 2.8e-15 56.0 0.0 3.7e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEP60299.1 - 1.5e-08 34.7 0.0 1.9e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEP60299.1 - 5.9e-07 29.5 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP60299.1 - 2e-06 27.4 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KEP60299.1 - 0.00012 22.0 0.0 0.00015 21.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEP60299.1 - 0.003 17.4 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEP60299.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PEPCK_ATP PF01293.15 KEP60302.1 - 1.2e-149 498.8 0.0 1.4e-149 498.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase URO-D PF01208.12 KEP60303.1 - 1.7e-104 349.4 0.0 2.4e-104 348.9 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) ART PF01129.13 KEP60305.1 - 0.047 12.7 0.2 0.14 11.1 0.1 1.8 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase DUF572 PF04502.8 KEP60306.1 - 7.6 5.6 15.8 9.9 5.2 11.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hydrolase_6 PF13344.1 KEP60307.1 - 7.5e-28 96.3 0.0 1.7e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEP60307.1 - 2.2e-12 46.4 0.0 5.4e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KEP60307.1 - 1.1e-10 42.0 0.1 0.00015 22.0 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEP60307.1 - 1.5e-09 38.5 0.0 9.2e-09 36.0 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase B12-binding PF02310.14 KEP60307.1 - 0.045 13.6 0.1 0.21 11.4 0.0 2.2 3 0 0 3 3 3 0 B12 binding domain Proteasome PF00227.21 KEP60310.1 - 2.9e-37 127.8 0.0 3.3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin_N PF00134.18 KEP60311.1 - 3.9e-06 26.4 0.0 6.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RecO_C PF02565.10 KEP60311.1 - 0.011 15.5 0.3 0.029 14.2 0.2 1.7 1 0 0 1 1 1 0 Recombination protein O C terminal MIF PF01187.13 KEP60313.1 - 1e-18 67.4 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 KEP60313.1 - 1.1e-05 24.9 0.0 0.03 13.9 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme BNR_2 PF13088.1 KEP60314.1 - 2.3e-06 27.0 0.0 0.046 13.0 0.0 3.7 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KEP60314.1 - 6.5e-05 22.1 19.3 0.3 11.0 0.3 7.4 8 0 0 8 8 8 3 BNR/Asp-box repeat BNR_3 PF13859.1 KEP60314.1 - 0.0015 17.6 0.4 0.12 11.4 0.0 3.4 4 0 0 4 4 4 1 BNR repeat-like domain Metallophos PF00149.23 KEP60315.1 - 4e-37 127.5 0.2 7.7e-37 126.6 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.1 KEP60315.1 - 5.4e-34 115.7 10.1 7.3e-08 32.0 0.2 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KEP60315.1 - 7.4e-33 111.9 3.1 5.4e-06 26.2 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KEP60315.1 - 1.3e-32 111.2 11.1 3e-06 27.2 0.0 7.8 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_2 PF07646.10 KEP60315.1 - 3.2e-23 80.5 10.7 7.1e-07 28.7 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KEP60315.1 - 1.1e-19 69.6 7.3 0.00025 21.0 0.2 7.0 5 2 2 7 7 7 4 Kelch motif Kelch_1 PF01344.20 KEP60315.1 - 1.4e-15 56.5 6.2 0.00015 21.1 0.0 6.5 6 0 0 6 6 6 3 Kelch motif RAG2 PF03089.9 KEP60315.1 - 2.6e-05 23.1 0.1 0.43 9.2 0.0 3.6 4 0 0 4 4 4 2 Recombination activating protein 2 AP2 PF00847.15 KEP60316.1 - 2.4e-07 30.7 0.2 6.3e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 AP2 domain SPT2 PF08243.6 KEP60317.1 - 7.2e-08 32.7 6.4 7.2e-08 32.7 4.4 2.7 3 0 0 3 3 3 1 SPT2 chromatin protein Octopine_DH PF02317.12 KEP60318.1 - 4.6e-31 107.5 0.0 6.4e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.12 KEP60318.1 - 0.00019 21.7 0.0 0.00036 20.9 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KEP60318.1 - 0.00034 20.3 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YjeF_N PF03853.10 KEP60318.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus ApbA PF02558.11 KEP60318.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.12 KEP60318.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase Pkinase_Tyr PF07714.12 KEP60319.1 - 2.6e-13 49.6 0.0 5.2e-09 35.5 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.20 KEP60319.1 - 2.4e-07 30.1 0.0 1.5e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain MORN PF02493.15 KEP60319.1 - 1.9 8.3 6.7 0.52 10.1 0.8 3.0 3 0 0 3 3 3 0 MORN repeat Tcf25 PF04910.9 KEP60320.1 - 5.3e-76 255.8 4.4 7.3e-76 255.4 3.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.1 KEP60320.1 - 0.00072 19.4 0.9 0.0021 17.9 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEP60320.1 - 0.056 13.5 0.5 0.89 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEP60320.1 - 0.21 11.8 0.7 1.3 9.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Menin PF05053.8 KEP60320.1 - 3.6 5.6 11.9 7.3 4.6 8.0 1.5 2 0 0 2 2 2 0 Menin PITH PF06201.8 KEP60322.1 - 1.4e-36 125.5 0.0 1.8e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain AAA_33 PF13671.1 KEP60323.1 - 2.3e-27 95.6 0.4 5.3e-27 94.4 0.3 1.6 1 0 0 1 1 1 1 AAA domain SPRY PF00622.23 KEP60323.1 - 6.7e-18 64.9 0.0 1.5e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 SPRY domain AAA_18 PF13238.1 KEP60323.1 - 0.0099 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEP60323.1 - 0.011 14.7 0.1 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 KEP60323.1 - 0.053 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ThiF PF00899.16 KEP60324.1 - 1.7e-46 157.4 3.0 1.9e-34 118.3 0.1 3.1 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 KEP60324.1 - 6e-33 112.2 9.7 5.4e-22 77.1 0.1 3.1 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KEP60324.1 - 2.9e-30 105.0 0.0 6e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KEP60324.1 - 5.9e-20 70.3 4.9 6.6e-20 70.2 1.8 2.3 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site Tap-RNA_bind PF09162.5 KEP60324.1 - 0.037 13.6 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Tap, RNA-binding TrkA_N PF02254.13 KEP60324.1 - 0.064 13.2 2.9 0.36 10.8 0.0 3.2 3 1 0 3 3 3 0 TrkA-N domain PBP PF01161.15 KEP60325.1 - 0.0022 17.8 0.1 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Vps51 PF08700.6 KEP60326.1 - 0.0034 17.1 0.1 0.0034 17.1 0.1 2.0 2 0 0 2 2 2 1 Vps51/Vps67 Voltage_CLC PF00654.15 KEP60327.1 - 8.2e-72 242.1 24.3 8.2e-72 242.1 16.8 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KEP60327.1 - 0.15 11.9 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 CBS domain HEAT_2 PF13646.1 KEP60328.1 - 2.4e-24 85.3 6.4 1.2e-12 47.9 0.0 3.9 3 1 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 KEP60328.1 - 2.5e-16 58.4 6.4 0.00091 19.4 0.0 5.7 5 0 0 5 5 5 3 PBS lyase HEAT-like repeat HEAT PF02985.17 KEP60328.1 - 1.2e-06 28.1 4.7 0.76 10.0 0.0 6.3 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KEP60328.1 - 0.00012 22.4 7.5 0.1 13.1 0.0 4.9 3 3 2 5 5 5 2 HEAT-like repeat Arm PF00514.18 KEP60328.1 - 0.0011 18.7 1.2 0.38 10.6 0.0 3.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat UPF0147 PF03685.8 KEP60328.1 - 0.082 12.7 0.0 1.3 8.9 0.0 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0147) RuvA_C PF07499.8 KEP60328.1 - 0.43 10.7 3.1 0.5 10.5 0.0 2.5 2 0 0 2 2 2 0 RuvA, C-terminal domain LOH1CR12 PF10158.4 KEP60330.1 - 0.064 13.0 0.1 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 Tumour suppressor protein DUF3136 PF11334.3 KEP60330.1 - 0.18 11.2 1.3 0.53 9.7 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3136) ABC2_membrane PF01061.19 KEP60331.1 - 1.9e-26 92.5 19.1 1.9e-26 92.5 13.3 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KEP60331.1 - 1.1e-21 77.5 0.0 1.9e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEP60331.1 - 3.9e-07 30.3 0.0 0.00071 19.6 0.0 2.2 1 1 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KEP60331.1 - 7.1e-06 25.2 19.2 1.1e-05 24.6 13.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.11 KEP60331.1 - 0.00017 20.7 0.1 0.00039 19.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEP60331.1 - 0.0048 16.3 0.1 0.045 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEP60331.1 - 0.0067 16.4 0.1 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF1388 PF07142.7 KEP60331.1 - 0.024 14.3 0.5 0.053 13.2 0.3 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) PDR_CDR PF06422.7 KEP60331.1 - 0.03 13.9 0.0 0.078 12.6 0.0 1.7 1 0 0 1 1 1 0 CDR ABC transporter AAA_29 PF13555.1 KEP60331.1 - 0.037 13.5 0.2 0.084 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 KEP60331.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KEP60331.1 - 0.094 12.6 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 KEP60331.1 - 0.097 12.1 0.3 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KEP60331.1 - 0.1 12.1 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KEP60331.1 - 0.14 13.0 0.0 0.38 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEP60331.1 - 0.22 11.8 0.0 0.41 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KEP60331.1 - 1.1 8.8 3.2 0.42 10.2 0.2 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 PAP_assoc PF03828.14 KEP60332.1 - 2.3e-07 30.6 0.0 1.3e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase Ligase_CoA PF00549.14 KEP60333.1 - 3.8e-26 91.5 0.1 6.2e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KEP60333.1 - 4e-25 88.1 0.6 2e-24 85.9 0.0 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 KEP60333.1 - 1.4e-10 40.9 0.0 2.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KEP60333.1 - 0.0017 18.4 0.2 0.011 15.9 0.0 2.4 3 1 1 4 4 4 1 CoA binding domain HECT_2 PF09814.4 KEP60334.1 - 4.8e-14 51.8 1.8 4.3e-08 32.2 0.5 2.3 2 1 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DZR PF12773.2 KEP60334.1 - 0.13 12.0 6.2 1 9.2 1.1 3.1 2 1 0 2 2 2 0 Double zinc ribbon AP2 PF00847.15 KEP60337.1 - 3.1e-09 36.8 0.6 6.3e-09 35.8 0.4 1.6 1 0 0 1 1 1 1 AP2 domain SAPS PF04499.10 KEP60337.1 - 7.8 5.0 4.0 12 4.3 2.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MutS_V PF00488.16 KEP60338.1 - 1.6e-82 276.4 0.0 2.4e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEP60338.1 - 1e-38 133.1 1.1 2.5e-38 131.9 0.7 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KEP60338.1 - 2.2e-31 108.2 0.0 4.5e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KEP60338.1 - 3.2e-07 30.4 0.2 1.1e-06 28.7 0.2 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KEP60338.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPR_3 PF13812.1 KEP60339.1 - 0.0022 18.1 0.3 0.67 10.3 0.0 3.9 3 0 0 3 3 3 1 Pentatricopeptide repeat domain Apt1 PF10351.4 KEP60339.1 - 0.69 8.6 2.5 0.89 8.3 1.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2217 PF10265.4 KEP60339.1 - 1.6 7.3 5.6 2.8 6.6 3.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Period_C PF12114.3 KEP60339.1 - 5.5 6.5 14.5 12 5.4 10.0 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RRM_5 PF13893.1 KEP60340.1 - 1.3e-33 114.5 0.2 1.2e-11 44.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60340.1 - 1e-26 92.6 0.1 1.5e-10 40.9 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP60340.1 - 7.2e-26 89.6 0.0 3e-08 33.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEP60340.1 - 0.015 15.0 0.0 2.2 8.0 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 RRM_3 PF08777.6 KEP60340.1 - 0.028 14.2 0.0 0.76 9.6 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif Peptidase_M17 PF00883.16 KEP60341.1 - 1.7e-120 401.6 2.9 2.3e-120 401.1 2.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KEP60341.1 - 1.1e-06 28.3 2.9 1.5e-06 28.0 0.4 2.4 3 0 0 3 3 3 1 Cytosol aminopeptidase family, N-terminal domain Mucin PF01456.12 KEP60343.1 - 0.065 13.0 0.1 0.065 13.0 0.1 2.5 2 1 1 3 3 3 0 Mucin-like glycoprotein V_ATPase_I PF01496.14 KEP60344.1 - 2.6e-149 498.4 0.0 3.1e-145 485.0 0.0 2.5 2 1 0 2 2 2 2 V-type ATPase 116kDa subunit family DUF4227 PF14004.1 KEP60344.1 - 0.98 9.2 5.0 5.6 6.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) CS PF04969.11 KEP60345.1 - 5.7e-06 26.7 0.0 2.2e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 CS domain UMPH-1 PF05822.7 KEP60345.1 - 0.0049 16.2 0.5 0.0049 16.2 0.3 1.5 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) NinG PF05766.7 KEP60345.1 - 0.021 14.6 2.1 0.037 13.7 1.4 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein SR-25 PF10500.4 KEP60345.1 - 5.2 6.4 15.9 0.058 12.8 4.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Med19 PF10278.4 KEP60346.1 - 0.041 13.5 9.7 0.056 13.1 6.8 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4662 PF15578.1 KEP60346.1 - 4.4 6.8 7.4 4.6 6.7 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Trypsin_2 PF13365.1 KEP60347.1 - 1.4e-14 54.1 0.3 2.6e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KEP60347.1 - 2.8e-14 53.2 0.1 5.1e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 KEP60347.1 - 1.5e-05 24.8 1.0 0.00011 21.9 0.4 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 KEP60347.1 - 0.068 13.3 0.1 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 KEP60347.1 - 0.072 11.5 0.6 1.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Peptidase S46 Suc_Fer-like PF06999.7 KEP60347.1 - 0.31 11.0 2.8 0.4 10.6 0.3 2.2 2 0 0 2 2 2 0 Sucrase/ferredoxin-like WD40 PF00400.27 KEP60348.1 - 1.6e-37 126.0 7.4 3.2e-09 36.3 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KEP60348.1 - 1.8e-08 33.0 0.2 0.00026 19.2 0.1 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KEP60348.1 - 0.013 14.9 0.1 0.89 8.9 0.0 2.7 1 1 1 2 2 2 0 PQQ-like domain LisH PF08513.6 KEP60348.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 LisH PQQ_3 PF13570.1 KEP60348.1 - 0.2 11.9 1.1 7.4 7.0 0.0 3.2 4 0 0 4 4 4 0 PQQ-like domain MFS_1 PF07690.11 KEP60349.1 - 4.6e-10 38.7 37.0 2.4e-07 29.8 1.1 3.3 3 1 1 4 4 4 2 Major Facilitator Superfamily ATG27 PF09451.5 KEP60349.1 - 0.0055 15.9 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 Patched PF02460.13 KEP60350.1 - 2.3e-99 333.4 0.0 1e-98 331.3 0.0 1.8 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KEP60350.1 - 3.6e-31 107.6 0.2 3.6e-31 107.6 0.1 2.9 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 KEP60350.1 - 0.16 9.3 16.0 4.3 4.5 11.1 2.3 3 0 0 3 3 3 0 AcrB/AcrD/AcrF family DnaJ PF00226.26 KEP60351.1 - 1.3e-15 56.8 0.1 2.5e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain adh_short PF00106.20 KEP60352.1 - 3.1e-19 69.5 0.0 9e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEP60352.1 - 4.9e-07 29.7 0.0 7.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEP60352.1 - 9.7e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NUDIX PF00293.23 KEP60353.1 - 2.4e-06 27.2 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain 2OG-FeII_Oxy PF03171.15 KEP60355.1 - 1.4e-09 38.1 0.0 2.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KEP60355.1 - 3.8e-08 33.7 0.0 7.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEP60355.1 - 0.0055 16.3 0.1 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mnd1 PF03962.10 KEP60357.1 - 5.5e-41 140.3 2.1 6.6e-41 140.0 1.5 1.1 1 0 0 1 1 1 1 Mnd1 family DSBA PF01323.15 KEP60357.1 - 0.0056 16.2 1.5 0.0079 15.7 0.2 1.7 2 0 0 2 2 2 1 DSBA-like thioredoxin domain GrpB PF04229.9 KEP60357.1 - 0.087 12.5 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 GrpB protein CotH PF08757.6 KEP60357.1 - 0.1 11.8 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 CotH protein DUF3253 PF11625.3 KEP60357.1 - 0.16 11.9 0.6 0.3 10.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Cytochrom_B562 PF07361.6 KEP60357.1 - 0.34 11.3 7.4 19 5.7 0.2 3.2 2 1 1 3 3 3 0 Cytochrome b562 DUF848 PF05852.6 KEP60357.1 - 0.44 10.3 4.9 0.28 11.0 2.1 1.6 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) YtxH PF12732.2 KEP60357.1 - 1.9 8.9 5.0 10 6.5 0.0 2.6 2 1 0 2 2 2 0 YtxH-like protein EMP70 PF02990.11 KEP60358.1 - 1.2e-181 604.6 4.0 1.8e-181 604.1 2.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Clathrin PF00637.15 KEP60360.1 - 4.9e-177 580.5 25.9 3.5e-31 107.7 0.0 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KEP60360.1 - 2.9e-26 91.1 0.3 2.9e-26 91.1 0.2 3.0 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.15 KEP60360.1 - 8.6e-07 28.8 0.0 0.0034 17.5 0.0 4.1 4 0 0 4 4 4 1 Clathrin propeller repeat Coatomer_WDAD PF04053.9 KEP60360.1 - 5.1e-06 25.5 0.7 0.062 12.0 0.0 2.9 2 0 0 2 2 2 2 Coatomer WD associated region PQQ PF01011.16 KEP60360.1 - 0.073 12.6 0.2 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 PQQ enzyme repeat TPR_2 PF07719.12 KEP60360.1 - 0.096 12.6 0.0 0.096 12.6 0.0 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP60360.1 - 1 9.0 0.0 1 9.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP60360.1 - 4.6 8.1 26.0 24 5.9 0.3 9.7 11 2 1 12 12 12 0 Tetratricopeptide repeat PPDK_N PF01326.14 KEP60361.1 - 3.6e-47 161.0 1.3 2.4e-45 155.0 0.1 2.5 2 0 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.14 KEP60361.1 - 5.1e-19 67.6 0.0 1e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Aminotran_1_2 PF00155.16 KEP60362.1 - 4.1e-44 151.0 0.0 1.9e-24 86.2 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEP60362.1 - 7.5e-05 21.1 0.0 0.012 13.9 0.0 2.3 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KEP60362.1 - 0.00044 18.9 0.0 0.078 11.5 0.0 2.1 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Herpes_U15 PF05613.6 KEP60362.1 - 0.0015 18.8 0.1 2.5 8.4 0.0 2.5 2 0 0 2 2 2 2 Human herpesvirus U15 protein DegT_DnrJ_EryC1 PF01041.12 KEP60362.1 - 0.12 11.4 0.0 0.54 9.2 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KEP60363.1 - 4.8e-42 144.2 0.0 7.7e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEP60363.1 - 6.5e-05 21.3 0.0 0.00017 20.0 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KEP60363.1 - 0.0013 17.4 0.0 0.012 14.2 0.0 2.0 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 KEP60363.1 - 0.12 11.3 0.0 0.47 9.4 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family HEAT PF02985.17 KEP60364.1 - 2.8 8.2 11.9 33 4.9 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat zf-HC5HC2H_2 PF13832.1 KEP60365.1 - 1.7e-17 63.4 8.0 4.4e-17 62.0 0.9 3.3 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEP60365.1 - 8.8e-15 54.6 0.0 8.8e-15 54.6 0.0 3.8 3 2 1 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.24 KEP60365.1 - 1.1e-10 41.0 27.0 4.5e-09 35.8 5.8 4.1 4 0 0 4 4 4 2 PHD-finger PHD_2 PF13831.1 KEP60365.1 - 1.1e-08 34.2 6.8 1.1e-08 34.2 4.7 2.9 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.17 KEP60365.1 - 0.027 14.2 0.8 0.027 14.2 0.5 4.2 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4pol PF14260.1 KEP60365.1 - 0.41 10.6 0.1 0.41 10.6 0.0 3.9 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Skp1_POZ PF03931.10 KEP60368.1 - 0.00016 21.6 0.0 0.00049 20.1 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Coiled PF05710.7 KEP60368.1 - 0.0081 16.6 12.4 0.018 15.5 8.6 1.5 1 0 0 1 1 1 1 Coiled coil Chorion_2 PF03964.10 KEP60368.1 - 0.1 13.1 9.9 0.19 12.2 6.9 1.5 1 0 0 1 1 1 0 Chorion family 2 DUF2217 PF10265.4 KEP60368.1 - 0.49 9.1 4.8 0.54 8.9 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 KEP60368.1 - 3.5 5.7 10.9 4.1 5.5 7.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Myosin_head PF00063.16 KEP60369.1 - 8.5e-29 100.1 0.0 2.8e-22 78.6 0.0 3.3 3 0 0 3 3 3 3 Myosin head (motor domain) RCC1 PF00415.13 KEP60369.1 - 6.5e-23 80.6 15.8 7.4e-07 29.2 0.0 7.5 8 1 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP60369.1 - 2.7e-06 26.8 22.2 0.014 15.0 0.9 5.9 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 KEP60369.1 - 0.00011 21.4 46.9 0.016 14.7 1.0 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif zf-RING_2 PF13639.1 KEP60370.1 - 4.7e-12 45.5 10.3 1e-11 44.4 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP60370.1 - 6.3e-07 29.4 6.1 1.6e-06 28.1 4.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEP60370.1 - 8.5e-07 28.8 9.2 1.9e-06 27.7 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP60370.1 - 2.3e-06 27.1 5.2 4.2e-06 26.3 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP60370.1 - 7.2e-05 22.4 6.8 0.00017 21.2 4.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEP60370.1 - 0.0012 18.4 9.5 0.0025 17.4 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KEP60370.1 - 0.013 15.2 3.4 0.026 14.2 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 KEP60370.1 - 0.21 11.4 7.9 0.027 14.3 2.5 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEP60370.1 - 0.55 9.8 5.0 1.2 8.7 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KEP60370.1 - 0.56 9.9 5.8 1.2 8.8 4.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Ldh_1_C PF02866.13 KEP60371.1 - 4.8e-35 120.8 0.0 7.7e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KEP60371.1 - 2.7e-34 117.9 0.2 4.7e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 KEP60371.1 - 0.017 14.4 0.1 0.049 12.9 0.1 1.7 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase F420_oxidored PF03807.12 KEP60371.1 - 0.14 12.6 1.8 0.27 11.6 0.4 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 KEP60372.1 - 2.6e-79 266.0 0.0 4.3e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60372.1 - 1.3e-44 152.2 0.0 1.8e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEP60372.1 - 0.00018 20.6 0.2 0.0004 19.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEP60372.1 - 0.00025 20.7 0.2 0.00041 19.9 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KEP60372.1 - 0.00086 19.1 0.1 0.0039 16.9 0.0 2.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP60372.1 - 0.0056 15.6 0.0 0.0096 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 KEP60372.1 - 0.07 11.6 0.2 0.098 11.2 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC V_ATPase_I PF01496.14 KEP60373.1 - 0.058 11.2 3.0 0.085 10.6 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3373 PF11853.3 KEP60373.1 - 0.19 10.2 5.3 0.27 9.7 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF2680 PF10925.3 KEP60373.1 - 4.2 7.3 8.5 0.38 10.6 0.4 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2680) TBP PF00352.16 KEP60375.1 - 1.2e-34 117.4 0.1 4.9e-16 57.8 0.0 3.1 3 0 0 3 3 3 3 Transcription factor TFIID (or TATA-binding protein, TBP) SNF2_N PF00176.18 KEP60376.1 - 6.8e-45 153.1 0.0 1.4e-44 152.1 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KEP60376.1 - 6e-06 25.2 0.0 1.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KEP60376.1 - 6e-05 22.8 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mon1 PF03164.9 KEP60377.1 - 3.9e-69 233.2 0.1 3e-35 121.6 0.0 2.1 2 0 0 2 2 2 2 Trafficking protein Mon1 PTS_IIB PF02302.12 KEP60377.1 - 0.062 13.7 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Not1 PF04054.10 KEP60379.1 - 7.7e-126 419.9 0.6 7.1e-125 416.7 0.4 2.2 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KEP60379.1 - 1.1e-54 184.0 3.9 1.9e-54 183.3 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Adeno_52K PF03052.10 KEP60380.1 - 1.7 7.8 6.0 2.2 7.4 0.3 2.3 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa Dynein_light PF01221.13 KEP60382.1 - 2.1e-14 53.2 0.1 2.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ist1 PF03398.9 KEP60383.1 - 1e-40 138.8 6.6 1.4e-40 138.4 4.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Chorein_N PF12624.2 KEP60384.1 - 4.6e-32 110.0 0.0 9.2e-32 109.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 KEP60384.1 - 3.8e-05 23.0 0.0 8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 KEP60384.1 - 0.018 15.1 0.1 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 ATG C terminal domain Rer1 PF03248.8 KEP60385.1 - 4.5e-61 205.4 6.3 6.1e-61 205.0 4.4 1.1 1 0 0 1 1 1 1 Rer1 family ATP-synt_C PF00137.16 KEP60387.1 - 2.4e-32 110.6 22.0 1.6e-16 59.8 2.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.19 KEP60387.1 - 0.32 10.6 3.9 2.2 7.9 1.9 2.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ABC2_membrane_4 PF12730.2 KEP60387.1 - 1.9 7.5 8.7 0.1 11.7 0.6 2.4 3 0 0 3 3 3 0 ABC-2 family transporter protein RRM_1 PF00076.17 KEP60389.1 - 1.9e-13 49.8 0.0 2.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60389.1 - 2e-06 27.6 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEP60389.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 KEP60389.1 - 0.031 14.1 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-MYND PF01753.13 KEP60393.1 - 1.5e-05 24.7 1.8 1.5e-05 24.7 1.3 2.2 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KEP60393.1 - 0.013 15.3 0.8 0.036 13.9 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ERM PF00769.14 KEP60394.1 - 3.4 7.1 13.4 3.8 6.9 0.8 2.3 1 1 0 2 2 2 0 Ezrin/radixin/moesin family IMCp PF12314.3 KEP60395.1 - 0.69 10.0 4.3 2.3 8.4 2.8 2.0 1 1 0 1 1 1 0 Inner membrane complex protein YTV PF07639.6 KEP60395.1 - 2.2 8.0 9.8 3.9 7.2 0.5 3.2 2 1 0 2 2 2 0 YTV Kinase-like PF14531.1 KEP60397.1 - 6.9e-89 297.6 0.0 8.2e-89 297.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP60397.1 - 0.00028 20.1 0.0 0.00096 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain GDA1_CD39 PF01150.12 KEP60398.1 - 1.4e-26 92.9 0.0 1.5e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family FliG_C PF01706.11 KEP60399.1 - 1.7 8.6 9.0 5.5 7.0 0.5 2.6 2 1 1 3 3 3 0 FliG C-terminal domain DUF4307 PF14155.1 KEP60399.1 - 3.2 7.5 17.9 2.3 8.0 1.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4307) Apo-CIII PF05778.7 KEP60399.1 - 4.5 6.7 5.7 12 5.4 0.4 2.4 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) DUF2774 PF11242.3 KEP60399.1 - 5.7 6.9 11.3 5.2 7.1 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2774) SAP25 PF15476.1 KEP60400.1 - 0.078 12.4 0.1 0.09 12.2 0.1 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Kinase-like PF14531.1 KEP60401.1 - 1.6e-71 240.6 0.0 1.8e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP60401.1 - 0.017 14.2 0.0 0.066 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain UPF0240 PF06784.6 KEP60402.1 - 0.13 11.9 0.8 0.18 11.5 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) bZIP_2 PF07716.10 KEP60403.1 - 0.17 11.7 1.6 0.24 11.2 1.1 1.2 1 0 0 1 1 1 0 Basic region leucine zipper SAG PF04092.8 KEP60406.1 - 2.7e-06 27.7 6.2 3.9e-06 27.2 4.3 1.3 1 0 0 1 1 1 1 SRS domain SAG PF04092.8 KEP60407.1 - 7.3e-53 178.1 21.9 2.7e-31 108.5 5.5 2.3 2 0 0 2 2 2 2 SRS domain PAAR_motif PF05488.8 KEP60407.1 - 0.018 15.0 0.7 0.068 13.1 0.5 2.0 1 0 0 1 1 1 0 PAAR motif SSI PF00720.12 KEP60408.1 - 0.16 11.9 4.7 2.3 8.2 0.4 2.4 1 1 1 2 2 2 0 Subtilisin inhibitor-like Shugoshin_C PF07557.6 KEP60413.1 - 0.028 13.8 0.2 0.072 12.5 0.1 1.7 1 0 0 1 1 1 0 Shugoshin C terminus PAN_1 PF00024.21 KEP60415.1 - 1.6e-18 66.1 16.0 5.1e-07 29.3 1.6 3.1 2 1 1 3 3 3 3 PAN domain PAN_4 PF14295.1 KEP60415.1 - 9.4e-14 50.8 19.6 6.5e-08 32.1 1.8 3.8 3 1 0 3 3 3 3 PAN domain PAN_3 PF08277.7 KEP60415.1 - 1.6e-09 37.2 12.0 7.1e-06 25.5 0.9 3.3 3 0 0 3 3 3 2 PAN-like domain PAN_2 PF08276.6 KEP60415.1 - 5.7e-05 22.8 14.3 0.19 11.6 3.2 3.3 3 0 0 3 3 3 3 PAN-like domain MANEC PF07502.9 KEP60415.1 - 0.00063 19.6 11.7 0.6 10.1 0.3 3.6 3 1 0 3 3 3 3 MANEC domain DUF4140 PF13600.1 KEP60416.1 - 0.11 12.9 0.3 2.4 8.6 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 KEP60416.1 - 0.24 10.9 1.2 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator PXA PF02194.10 KEP60417.1 - 0.7 9.4 3.2 0.92 9.0 2.2 1.2 1 0 0 1 1 1 0 PXA domain Hep_59 PF07052.6 KEP60417.1 - 0.84 10.0 4.0 1 9.7 2.8 1.3 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 GRIM-19 PF06212.7 KEP60417.1 - 4.4 7.0 5.5 6.1 6.5 1.4 2.0 1 1 1 2 2 2 0 GRIM-19 protein Kinase-like PF14531.1 KEP60419.1 - 5.8e-57 192.8 0.0 7.5e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like SAG PF04092.8 KEP60421.1 - 1.4e-33 115.9 16.0 8.2e-21 74.6 4.0 2.2 2 0 0 2 2 2 2 SRS domain Pertus-S4-tox PF09275.5 KEP60421.1 - 0.11 12.5 0.0 12 6.0 0.1 2.4 1 1 1 2 2 2 0 Pertussis toxin S4 subunit NAD_Gly3P_dh_C PF07479.9 KEP60422.1 - 0.0068 16.1 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Phage_integrase PF00589.17 KEP60423.1 - 7.1e-21 74.6 0.0 8.4e-17 61.3 0.0 2.4 2 0 0 2 2 2 2 Phage integrase family Phage_int_SAM_1 PF02899.12 KEP60423.1 - 1.7e-09 37.7 4.1 2.5e-09 37.1 0.1 2.9 3 1 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 KEP60423.1 - 2.2e-05 24.6 0.1 0.00062 20.0 0.0 2.6 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain DUF736 PF05284.7 KEP60424.1 - 9.8e-34 115.4 0.0 1.1e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF736) NAD_Gly3P_dh_C PF07479.9 KEP60425.1 - 5.9e-44 149.3 0.0 7.3e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Phage_int_SAM_1 PF02899.12 KEP60428.1 - 2.8e-17 62.6 1.0 4.4e-17 62.0 0.7 1.3 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.17 KEP60428.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family DUF372 PF04036.7 KEP60429.1 - 0.0027 17.1 0.7 24 4.5 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF372) LuxS PF02664.10 KEP60429.1 - 0.026 14.0 0.0 35 3.9 0.0 3.1 3 0 0 3 3 3 0 S-Ribosylhomocysteinase (LuxS) SprB PF13573.1 KEP60429.1 - 0.14 11.7 4.3 37 4.0 0.1 3.3 3 0 0 3 3 3 0 SprB repeat Zip PF02535.17 KEP60430.1 - 0.66 8.9 3.3 0.7 8.8 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter IstB_IS21 PF01695.12 KEP60431.1 - 3.8e-69 231.6 0.0 4.6e-69 231.3 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein IstB_IS21_ATP PF08483.6 KEP60431.1 - 3.8e-08 32.8 1.8 7.8e-08 31.8 1.3 1.5 1 0 0 1 1 1 1 IstB-like ATP binding N-terminal AAA_25 PF13481.1 KEP60431.1 - 0.00024 20.5 0.1 0.00043 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEP60431.1 - 0.00041 20.4 0.2 0.0027 17.8 0.0 2.3 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KEP60431.1 - 0.0008 19.4 0.1 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Bac_DnaA PF00308.13 KEP60431.1 - 0.0048 16.5 0.0 0.0068 16.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial dnaA protein PhoH PF02562.11 KEP60431.1 - 0.0057 15.9 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_17 PF13207.1 KEP60431.1 - 0.007 17.1 0.9 0.012 16.3 0.2 1.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEP60431.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KEP60431.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 KEP60431.1 - 0.055 13.6 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KEP60431.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 KEP60431.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEP60431.1 - 0.088 12.2 0.0 0.19 11.1 0.0 1.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 KEP60431.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEP60431.1 - 0.15 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase rve PF00665.21 KEP60432.1 - 9.4e-11 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 KEP60432.1 - 4.7e-05 22.8 0.6 4.7e-05 22.8 0.4 3.2 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.1 KEP60432.1 - 5e-05 22.7 2.9 0.0011 18.5 0.6 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain rve_3 PF13683.1 KEP60432.1 - 0.00016 21.1 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.1 KEP60432.1 - 0.00017 21.5 1.0 0.0022 17.9 0.0 3.2 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_24 PF13412.1 KEP60432.1 - 0.00024 20.4 0.0 0.00074 18.8 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.1 KEP60432.1 - 0.0003 20.8 0.6 0.0038 17.3 0.0 2.8 3 0 0 3 3 3 1 Winged helix-turn helix GerE PF00196.14 KEP60432.1 - 0.0013 18.0 0.0 0.0031 16.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 KEP60432.1 - 0.0014 18.0 0.1 0.0044 16.4 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.2 KEP60432.1 - 0.0016 18.0 0.2 0.0055 16.3 0.1 1.9 1 0 0 1 1 1 1 MarR family HTH_AsnC-type PF13404.1 KEP60432.1 - 0.011 15.2 0.4 0.038 13.5 0.3 2.0 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR_2 PF12802.2 KEP60433.1 - 0.0001 21.8 0.2 0.00019 21.0 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.1 KEP60433.1 - 0.00061 19.8 0.0 0.0015 18.6 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Replic_Relax PF13814.1 KEP60433.1 - 0.0067 16.2 0.1 0.0099 15.7 0.1 1.2 1 0 0 1 1 1 1 Replication-relaxation HTH_20 PF12840.2 KEP60433.1 - 0.041 13.6 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.16 KEP60433.1 - 0.044 13.2 0.2 0.071 12.5 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.1 KEP60433.1 - 0.056 12.8 0.1 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_12 PF08461.5 KEP60433.1 - 0.25 11.0 1.9 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain SAG PF04092.8 KEP60434.1 - 3.6e-51 172.7 17.1 3.3e-33 114.7 2.6 2.1 2 0 0 2 2 2 2 SRS domain HTH_Tnp_ISL3 PF13542.1 KEP60436.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF4332 PF14229.1 KEP60437.1 - 0.37 10.7 2.7 2.7 7.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Biopterin_H PF00351.16 KEP60438.1 - 3.6e-111 371.1 0.0 4.5e-111 370.8 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 KEP60438.1 - 6.5e-07 28.7 0.0 1.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain PAN_4 PF14295.1 KEP60439.1 - 4.2e-46 154.4 36.6 1.3e-11 43.9 1.3 5.9 5 0 0 5 5 5 5 PAN domain PAN_1 PF00024.21 KEP60439.1 - 4.3e-33 112.9 27.8 7.7e-07 28.7 0.7 5.4 5 0 0 5 5 5 5 PAN domain PAN_3 PF08277.7 KEP60439.1 - 0.11 12.1 31.0 0.23 11.0 0.7 5.0 5 0 0 5 5 5 0 PAN-like domain SAG PF04092.8 KEP60441.1 - 5.2e-10 39.7 14.7 0.00017 21.9 2.3 2.4 1 1 1 2 2 2 2 SRS domain Pacs-1 PF10254.4 KEP60442.1 - 0.08 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein TMV_coat PF00721.16 KEP60442.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Virus coat protein (TMV like) PAN_4 PF14295.1 KEP60443.1 - 1.6e-07 30.9 1.4 3.5e-07 29.8 1.0 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KEP60443.1 - 3.7e-06 26.6 2.0 4.9e-06 26.2 1.4 1.3 1 1 0 1 1 1 1 PAN domain PAN_3 PF08277.7 KEP60443.1 - 0.00093 18.7 0.5 0.0019 17.7 0.4 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_2 PF08276.6 KEP60443.1 - 0.0089 15.8 0.9 0.018 14.8 0.6 1.5 1 0 0 1 1 1 1 PAN-like domain CBM_1 PF00734.13 KEP60443.1 - 0.2 11.3 1.8 0.43 10.3 0.8 2.0 1 1 1 2 2 2 0 Fungal cellulose binding domain DUF3548 PF12068.3 KEP60447.1 - 0.037 13.3 0.1 0.089 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Val_tRNA-synt_C PF10458.4 KEP60447.1 - 2.7 8.1 6.2 0.44 10.6 0.7 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF3548 PF12068.3 KEP60448.1 - 0.097 11.9 0.1 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Val_tRNA-synt_C PF10458.4 KEP60449.1 - 0.02 14.9 0.9 0.09 12.8 0.1 2.6 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Kinetochor_Ybp2 PF08568.5 KEP60449.1 - 0.1 10.8 0.3 0.2 9.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin DUF2357 PF09823.4 KEP60449.1 - 0.33 9.9 5.7 0.08 12.0 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2357) PAN_4 PF14295.1 KEP60454.1 - 1.3e-107 351.3 159.7 7.7e-11 41.5 1.4 20.9 21 0 0 21 21 21 20 PAN domain PAN_1 PF00024.21 KEP60454.1 - 1.3e-87 287.6 117.8 1.8e-06 27.5 0.5 20.3 19 1 1 20 20 20 19 PAN domain DUF1379 PF07126.7 KEP60456.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1379) NRDE-2 PF08424.5 KEP60457.1 - 0.048 12.5 0.4 0.062 12.1 0.3 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference FYDLN_acid PF09538.5 KEP60457.1 - 0.07 13.7 10.7 0.11 13.0 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Gcd10p PF04189.8 KEP60457.1 - 0.093 11.8 3.8 0.12 11.4 2.6 1.1 1 0 0 1 1 1 0 Gcd10p family FHIPEP PF00771.15 KEP60457.1 - 0.094 11.0 0.3 0.11 10.7 0.2 1.0 1 0 0 1 1 1 0 FHIPEP family Macoilin PF09726.4 KEP60457.1 - 0.34 9.1 7.4 0.39 8.9 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Rtf2 PF04641.7 KEP60457.1 - 0.38 9.9 9.5 0.46 9.6 6.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NARP1 PF12569.3 KEP60457.1 - 0.52 8.9 10.8 0.61 8.7 7.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1510 PF07423.6 KEP60457.1 - 0.65 9.3 9.4 0.8 9.0 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) eIF3_subunit PF08597.5 KEP60457.1 - 0.92 9.0 15.4 1.4 8.4 10.7 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TRAP_alpha PF03896.11 KEP60457.1 - 5.2 5.9 6.7 6.4 5.6 4.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2800 PF10926.3 KEP60461.1 - 6.2e-68 229.5 0.0 7e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2800) PDDEXK_1 PF12705.2 KEP60461.1 - 1.3e-10 41.0 0.0 2.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF2815 PF10991.3 KEP60462.1 - 3.9e-11 42.8 0.7 1e-10 41.4 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2815) DUF2312 PF10073.4 KEP60463.1 - 0.0044 16.3 0.6 0.0076 15.5 0.4 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) DNA_pol_A PF00476.15 KEP60465.1 - 4.6e-10 38.6 0.0 3e-06 26.1 0.0 3.2 2 1 0 2 2 2 2 DNA polymerase family A HTH_WhiA PF02650.9 KEP60465.1 - 0.068 13.5 0.2 0.39 11.1 0.0 2.2 1 1 1 2 2 2 0 WhiA C-terminal HTH domain Sigma70_r2 PF04542.9 KEP60466.1 - 4.7e-13 48.5 0.1 5.2e-13 48.3 0.1 1.0 1 0 0 1 1 1 1 Sigma-70 region 2 Herpes_UL95 PF03038.9 KEP60467.1 - 0.036 12.9 0.0 0.081 11.7 0.0 1.5 1 0 0 1 1 1 0 UL95 family SAG PF04092.8 KEP60470.1 - 6e-10 39.5 9.6 7.5e-07 29.5 0.7 2.4 3 0 0 3 3 3 2 SRS domain AAA_13 PF13166.1 KEP60470.1 - 0.015 13.7 1.9 0.025 13.0 1.3 1.2 1 0 0 1 1 1 0 AAA domain DUF759 PF05537.6 KEP60470.1 - 0.034 12.9 0.7 0.046 12.4 0.5 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Baculo_PEP_C PF04513.7 KEP60470.1 - 0.069 12.9 1.4 0.14 11.9 1.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UME PF08064.8 KEP60470.1 - 0.16 11.9 1.4 1.9 8.4 0.9 2.4 1 1 1 2 2 2 0 UME (NUC010) domain DUF948 PF06103.6 KEP60470.1 - 0.3 10.9 5.6 1.2 9.0 0.3 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SAG PF04092.8 KEP60471.1 - 5.4e-14 52.6 13.2 8.9e-06 26.0 0.5 3.2 3 0 0 3 3 3 3 SRS domain SAG PF04092.8 KEP60473.1 - 8.5e-66 219.9 35.4 7.4e-26 90.9 5.0 3.1 2 1 1 3 3 3 3 SRS domain DUF1929 PF09118.6 KEP60473.1 - 0.00029 20.8 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF1929) DUF1021 PF06257.6 KEP60473.1 - 0.0047 16.5 0.0 22 4.8 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1021) Levi_coat PF01819.12 KEP60473.1 - 0.013 15.0 1.9 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Levivirus coat protein DUF3277 PF11681.3 KEP60473.1 - 0.024 14.1 0.0 6.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) Ground-like PF04155.13 KEP60473.1 - 0.058 13.7 8.7 20 5.5 0.1 4.1 3 2 1 4 4 4 0 Ground-like domain SAG PF04092.8 KEP60474.1 - 3.4e-40 137.2 16.3 1.1e-26 93.6 0.6 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP60475.1 - 3e-40 137.4 25.5 7.8e-26 90.9 5.1 2.1 2 0 0 2 2 2 2 SRS domain CARDB PF07705.6 KEP60475.1 - 0.091 12.8 2.1 0.32 11.0 0.1 2.6 3 0 0 3 3 3 0 CARDB Osmo_CC PF08946.5 KEP60477.1 - 0.37 10.8 2.3 9 6.4 0.4 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DivIVA PF05103.8 KEP60477.1 - 1.4 8.9 4.3 1.4 9.0 1.4 2.1 2 0 0 2 2 2 0 DivIVA protein DLIC PF05783.6 KEP60477.1 - 1.6 7.3 4.5 0.91 8.1 0.6 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DUF342 PF03961.8 KEP60479.1 - 0.091 11.1 0.2 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_lysozyme PF00959.14 KEP60481.1 - 7.2e-05 23.0 0.3 0.0033 17.6 0.0 2.4 2 0 0 2 2 2 1 Phage lysozyme DUF2215 PF10225.4 KEP60481.1 - 0.074 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) DNA_primase_lrg PF04104.9 KEP60481.1 - 0.13 11.5 0.8 1.1 8.4 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Metallophos_2 PF12850.2 KEP60482.1 - 0.0019 18.0 0.0 0.012 15.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CHAP PF05257.11 KEP60483.1 - 3.3e-07 29.9 0.3 4.3e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 CHAP domain HTH_3 PF01381.17 KEP60484.1 - 1e-05 25.2 0.1 4.4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix HTH_26 PF13443.1 KEP60484.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain TAT_signal PF10518.4 KEP60484.1 - 0.064 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF2997 PF11211.3 KEP60485.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Phage_integrase PF00589.17 KEP60486.1 - 5.8e-16 58.6 0.0 1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Sigma70_r4_2 PF08281.7 KEP60489.1 - 2.2e-09 36.6 0.0 3.5e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.6 KEP60489.1 - 1.1e-05 25.1 0.1 1.2e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r2 PF04542.9 KEP60489.1 - 2.8e-05 23.6 0.2 5.5e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.11 KEP60489.1 - 0.015 14.5 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Dpy-30 PF05186.8 KEP60490.1 - 4.1e-14 51.7 0.1 7.1e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif ARGLU PF15346.1 KEP60490.1 - 0.0011 18.6 12.7 0.0021 17.8 8.8 1.4 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 DUF1451 PF07295.6 KEP60490.1 - 0.048 13.4 2.4 0.073 12.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Herpes_UL6 PF01763.11 KEP60490.1 - 0.064 11.4 1.0 0.07 11.2 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like OmpH PF03938.9 KEP60490.1 - 0.1 12.5 2.7 0.12 12.3 1.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) 2OG-FeII_Oxy_3 PF13640.1 KEP60490.1 - 0.12 12.8 0.1 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RIIa PF02197.12 KEP60490.1 - 0.22 10.9 0.2 0.22 10.9 0.1 3.1 4 0 0 4 4 4 0 Regulatory subunit of type II PKA R-subunit Atg14 PF10186.4 KEP60490.1 - 0.41 9.5 4.6 0.47 9.3 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GMP_synt_C PF00958.17 KEP60491.1 - 6.1e-37 125.2 0.1 1.3e-36 124.1 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 KEP60491.1 - 3.1e-35 121.3 0.0 4.4e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 KEP60491.1 - 3.5e-08 32.6 0.0 4.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KEP60491.1 - 2.1e-06 27.3 0.0 4.9e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 Asn_synthase PF00733.16 KEP60491.1 - 0.0003 20.3 0.1 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KEP60491.1 - 0.0024 16.4 0.0 0.007 14.9 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 KEP60491.1 - 0.011 15.0 0.0 3.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.9 KEP60491.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) zf-CHY PF05495.7 KEP60492.1 - 7.2e-16 58.1 19.6 7.2e-16 58.1 13.6 2.5 2 1 0 2 2 2 1 CHY zinc finger Nop14 PF04147.7 KEP60492.1 - 1.8 6.4 11.2 1.9 6.2 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family LAT PF15234.1 KEP60493.1 - 0.16 11.3 1.9 0.26 10.7 0.9 1.6 1 1 0 1 1 1 0 Linker for activation of T-cells Biopterin_H PF00351.16 KEP60494.1 - 2e-13 49.8 0.0 2.2e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase TraW_N PF12477.3 KEP60495.1 - 0.096 12.6 0.1 0.096 12.6 0.0 3.5 4 0 0 4 4 4 0 Sex factor F TraW protein N terminal DUF4355 PF14265.1 KEP60496.1 - 0.26 11.2 6.9 0.19 11.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) UPF0203 PF05254.7 KEP60496.1 - 0.44 10.4 5.4 6.2 6.7 0.5 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) PP2C PF00481.16 KEP60501.1 - 2.6e-65 220.3 0.0 9.1e-54 182.5 0.0 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.1 KEP60501.1 - 2.2e-05 23.9 0.0 0.003 16.9 0.0 2.6 2 1 0 2 2 2 2 Protein phosphatase 2C SAG PF04092.8 KEP60503.1 - 2.9e-38 131.0 15.9 1.8e-24 86.5 1.8 2.1 2 0 0 2 2 2 2 SRS domain C2-set_2 PF08205.7 KEP60503.1 - 0.0054 16.5 1.5 0.94 9.4 0.1 2.6 2 0 0 2 2 2 2 CD80-like C2-set immunoglobulin domain Ribosomal_L23 PF00276.15 KEP60505.1 - 8.2e-18 64.1 0.6 8.2e-18 64.1 0.4 2.4 2 2 1 3 3 3 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 KEP60505.1 - 1.2e-06 28.4 19.8 1.3e-05 25.0 13.7 2.5 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Levi_coat PF01819.12 KEP60505.1 - 9.7e-05 21.9 1.4 0.076 12.6 0.1 2.1 1 1 1 2 2 2 2 Levivirus coat protein TusA PF01206.12 KEP60505.1 - 0.016 14.8 0.1 0.56 9.8 0.1 2.3 1 1 1 2 2 2 0 Sulfurtransferase TusA Elong-fact-P_C PF09285.6 KEP60505.1 - 0.021 14.1 0.1 0.054 12.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor P, C-terminal YihI PF04220.7 KEP60505.1 - 2 7.7 5.0 8.3 5.7 3.5 1.8 1 1 0 1 1 1 0 Der GTPase activator (YihI) Pro_isomerase PF00160.16 KEP60506.1 - 6.6e-41 140.1 0.0 8.4e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ECH PF00378.15 KEP60509.1 - 1.4e-72 243.7 0.1 1.8e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KEP60509.1 - 0.081 12.7 0.1 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 eIF-3_zeta PF05091.7 KEP60510.1 - 2.6e-156 521.2 0.0 3.3e-93 313.0 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EI24 PF07264.6 KEP60512.1 - 0.11 11.9 0.6 0.58 9.5 0.2 1.9 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF3357 PF11837.3 KEP60512.1 - 0.34 10.7 2.4 0.35 10.7 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF3297 PF11730.3 KEP60514.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) MYCBPAP PF14646.1 KEP60517.1 - 7.3e-08 31.5 0.0 0.004 15.9 0.0 2.2 2 0 0 2 2 2 2 MYCBP-associated protein family DNA_pol_B PF00136.16 KEP60519.1 - 8e-128 427.1 0.0 1.2e-127 426.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_alpha_N PF12254.3 KEP60519.1 - 6.3e-16 57.9 8.2 1.8e-15 56.5 5.7 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.14 KEP60519.1 - 4.2e-13 48.8 0.0 1.4e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain Mic1 PF07035.7 KEP60519.1 - 0.25 10.6 1.0 0.54 9.6 0.7 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like zf-C3HC4 PF00097.20 KEP60520.1 - 1.5 8.5 5.9 29 4.4 4.1 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AhpC-TSA PF00578.16 KEP60521.1 - 2.6e-36 124.0 0.0 3.2e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEP60521.1 - 5.5e-17 61.6 0.0 6.7e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KEP60521.1 - 9.6e-15 53.9 0.1 2.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin KH_1 PF00013.24 KEP60522.1 - 1.7e-38 130.0 3.0 4.8e-15 54.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KEP60522.1 - 3.7e-29 99.8 6.2 1.2e-10 40.8 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KEP60522.1 - 2.6e-06 26.9 3.9 0.067 12.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KEP60522.1 - 5.8e-05 22.8 2.0 0.39 10.5 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain KH_4 PF13083.1 KEP60522.1 - 6.2e-05 22.5 0.2 4.4 7.0 0.0 3.3 3 0 0 3 3 3 3 KH domain zf-DHHC PF01529.15 KEP60523.1 - 2.2e-30 105.3 3.0 2.2e-30 105.3 2.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase MOR2-PAG1_N PF14222.1 KEP60524.1 - 0.7 8.4 0.0 1.3 7.6 0.0 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Cpn60_TCP1 PF00118.19 KEP60527.1 - 1.1e-117 393.6 0.7 1.2e-117 393.4 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ANKH PF07260.6 KEP60527.1 - 0.095 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) MgtC PF02308.11 KEP60528.1 - 0.13 12.0 4.6 0.48 10.2 0.4 2.1 2 0 0 2 2 2 0 MgtC family NAD_Gly3P_dh_N PF01210.18 KEP60529.1 - 6.9e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1084 PF06454.6 KEP60530.1 - 0.072 12.1 0.0 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) DUF21 PF01595.15 KEP60531.1 - 1.8e-28 99.0 3.8 3.1e-28 98.2 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KEP60531.1 - 0.0012 18.5 0.1 0.094 12.5 0.0 2.7 2 1 0 2 2 2 1 CBS domain Sporozoite_P67 PF05642.6 KEP60532.1 - 0.041 11.7 4.3 0.068 11.0 3.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DLL_N PF12413.3 KEP60532.1 - 0.11 13.5 0.5 0.25 12.4 0.3 1.5 1 0 0 1 1 1 0 Homeobox protein distal-less-like N terminal RCC1 PF00415.13 KEP60533.1 - 2.3e-32 110.9 14.3 8.2e-10 38.7 0.1 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP60533.1 - 1.2e-28 98.0 18.3 3.9e-09 35.8 1.2 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat ADK PF00406.17 KEP60534.1 - 6.3e-37 126.7 0.0 4.9e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KEP60534.1 - 4e-13 50.2 0.0 3.4e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEP60534.1 - 3.1e-08 33.6 0.5 8.1e-07 29.0 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEP60534.1 - 0.00025 21.3 0.0 0.001 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain CoaE PF01121.15 KEP60534.1 - 0.00026 20.4 1.1 0.0016 17.8 0.0 2.5 2 1 1 3 3 3 1 Dephospho-CoA kinase ABC_tran PF00005.22 KEP60534.1 - 0.0071 16.6 0.0 0.037 14.3 0.0 2.2 1 1 1 2 2 2 1 ABC transporter Thymidylate_kin PF02223.12 KEP60534.1 - 0.028 13.7 0.1 1.8 7.9 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase AAA_22 PF13401.1 KEP60534.1 - 0.045 13.9 0.0 0.17 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain SKI PF01202.17 KEP60534.1 - 0.057 13.2 0.1 0.91 9.3 0.0 2.7 2 1 0 2 2 2 0 Shikimate kinase Prog_receptor PF02161.10 KEP60535.1 - 0.019 13.7 3.6 0.026 13.3 2.5 1.1 1 0 0 1 1 1 0 Progesterone receptor Bap31 PF05529.7 KEP60535.1 - 0.022 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like EF_TS PF00889.14 KEP60536.1 - 4.3e-35 121.0 0.5 2.6e-20 72.6 0.0 3.2 3 0 0 3 3 3 3 Elongation factor TS UBA PF00627.26 KEP60536.1 - 0.00013 21.6 0.1 0.00046 19.9 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 KEP60536.1 - 0.00086 18.7 1.3 0.002 17.6 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain Pkinase PF00069.20 KEP60539.1 - 1.7e-60 204.4 0.0 1.9e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60539.1 - 2.8e-36 124.9 0.0 3.3e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP60539.1 - 0.0011 17.9 0.0 0.0024 16.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEP60539.1 - 0.0025 17.5 0.1 0.27 10.9 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEP60539.1 - 0.0036 16.3 0.0 0.0066 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UDG PF03167.14 KEP60540.1 - 4.4e-22 78.1 0.0 6.4e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RRM_1 PF00076.17 KEP60542.1 - 9.1e-46 153.3 0.0 1.1e-15 57.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60542.1 - 4.4e-36 122.6 0.0 2.4e-11 43.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP60542.1 - 1.3e-26 92.1 0.0 2.5e-11 43.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 KEP60542.1 - 0.00015 21.3 0.0 0.83 9.1 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF1866) RNA_bind PF08675.6 KEP60542.1 - 0.0076 16.2 0.0 7.4 6.6 0.0 2.8 3 0 0 3 3 3 2 RNA binding domain Limkain-b1 PF11608.3 KEP60542.1 - 0.015 15.0 0.1 0.77 9.5 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 Nup35_RRM_2 PF14605.1 KEP60542.1 - 0.016 14.9 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PCNA_N PF00705.13 KEP60544.1 - 6.8e-26 90.2 0.5 1.3e-25 89.3 0.3 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KEP60544.1 - 2.7e-12 46.7 0.0 1.7e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KEP60544.1 - 4.7e-06 25.9 0.1 1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Rad9 HIT PF01230.18 KEP60545.1 - 1.3e-21 76.9 0.0 1.8e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEP60545.1 - 2e-08 34.4 0.0 2.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Gal-bind_lectin PF00337.17 KEP60545.1 - 0.077 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Galactoside-binding lectin DUF3469 PF11952.3 KEP60546.1 - 1.2e-07 31.2 0.2 1.8e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3469) PRCC PF10253.4 KEP60546.1 - 1.8 9.2 6.2 2.5 8.7 4.3 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting UCR_hinge PF02320.11 KEP60547.1 - 1e-19 70.2 2.7 1.2e-19 69.9 1.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein TSP_1 PF00090.14 KEP60547.1 - 0.19 11.8 2.8 0.72 10.0 0.9 2.1 1 1 1 2 2 2 0 Thrombospondin type 1 domain Cmc1 PF08583.5 KEP60547.1 - 0.32 10.7 2.6 0.49 10.2 1.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GTP_EFTU PF00009.22 KEP60548.1 - 7.6e-26 90.7 0.0 1.3e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEP60548.1 - 1.5e-12 47.5 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain ATP_bind_1 PF03029.12 KEP60548.1 - 0.001 18.6 0.1 0.15 11.5 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KEP60548.1 - 0.0023 17.4 0.0 0.67 9.4 0.0 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.20 KEP60548.1 - 0.019 15.0 0.4 0.053 13.6 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Miro PF08477.8 KEP60548.1 - 0.03 14.8 0.1 0.13 12.7 0.1 2.1 1 1 0 1 1 1 0 Miro-like protein MobB PF03205.9 KEP60548.1 - 0.033 13.8 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 KEP60548.1 - 0.074 11.7 0.2 0.13 10.9 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DLIC PF05783.6 KEP60548.1 - 0.2 10.2 0.0 0.67 8.5 0.0 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) SAG PF04092.8 KEP60551.1 - 1.2e-56 190.4 22.1 1.1e-34 119.4 3.5 2.1 2 0 0 2 2 2 2 SRS domain Glyco_trans_1_4 PF13692.1 KEP60555.1 - 1.6e-10 41.2 0.1 1.4e-09 38.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KEP60555.1 - 0.028 13.8 0.0 0.071 12.5 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 D123 PF07065.9 KEP60556.1 - 1.3e-33 116.3 0.1 1.6e-19 70.1 0.0 4.3 3 1 0 3 3 3 3 D123 MFS_1 PF07690.11 KEP60557.1 - 3.2e-22 78.7 37.3 2e-13 49.7 1.7 3.6 3 1 1 4 4 4 3 Major Facilitator Superfamily OATP PF03137.15 KEP60557.1 - 1.4e-10 39.8 6.5 2.9e-05 22.3 0.5 3.5 2 2 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 KEP60557.1 - 6.8e-08 31.5 13.6 2e-07 29.9 0.2 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter HgmA PF04209.8 KEP60557.1 - 0.36 9.1 0.2 0.56 8.5 0.1 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Guanylate_cyc PF00211.15 KEP60558.1 - 9.4e-16 57.6 0.0 1.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pro_isomerase PF00160.16 KEP60560.1 - 3.2e-45 154.1 0.2 3.6e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YukC PF10140.4 KEP60562.1 - 0.25 9.8 0.3 0.39 9.2 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PIP5K PF01504.13 KEP60563.1 - 1e-75 254.1 0.0 1.6e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.27 KEP60563.1 - 0.00044 19.3 0.0 0.0012 17.9 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KEP60563.1 - 0.00055 20.0 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KEP60563.1 - 0.0016 17.9 0.3 0.0043 16.6 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KEP60563.1 - 0.0019 17.8 0.1 0.0078 16.0 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KEP60563.1 - 0.022 14.1 0.1 0.083 12.2 0.0 2.0 1 0 0 1 1 1 0 EF hand NADPH_Ox PF08414.5 KEP60563.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase DUF3021 PF11457.3 KEP60564.1 - 0.052 13.4 0.3 0.064 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF204 PF02659.10 KEP60564.1 - 0.2 11.8 3.0 0.31 11.1 1.6 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF DUF3040 PF11239.3 KEP60564.1 - 0.29 11.1 2.4 0.44 10.6 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF4282 PF14110.1 KEP60564.1 - 1.1 9.4 4.8 1.5 9.0 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Pkinase PF00069.20 KEP60565.1 - 2.4e-19 69.5 0.0 3.4e-18 65.7 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60565.1 - 6.4e-09 35.2 0.0 1.5e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP60565.1 - 1.1e-05 24.4 0.0 1.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KEP60565.1 - 0.001 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KEP60565.1 - 0.0035 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 KEP60565.1 - 0.019 14.2 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIIa PF02197.12 KEP60565.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Kdo PF06293.9 KEP60565.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADK PF00406.17 KEP60566.1 - 6.7e-07 29.2 0.0 0.0054 16.6 0.0 2.5 1 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 KEP60566.1 - 0.00016 22.4 0.0 0.0008 20.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEP60566.1 - 0.0096 15.0 0.7 0.063 12.3 0.0 2.4 3 0 0 3 3 3 1 Zeta toxin AAA_16 PF13191.1 KEP60566.1 - 0.015 15.2 0.1 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KEP60566.1 - 0.015 15.4 0.3 0.053 13.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEP60566.1 - 0.018 14.7 0.4 0.05 13.3 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain Mg_chelatase PF01078.16 KEP60566.1 - 0.043 12.9 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 KEP60566.1 - 0.048 12.5 0.0 0.38 9.5 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_18 PF13238.1 KEP60566.1 - 0.06 13.6 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEP60566.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEP60566.1 - 0.1 12.4 0.0 0.69 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.9 KEP60566.1 - 0.13 10.2 5.2 0.27 9.2 3.6 1.6 1 0 0 1 1 1 0 CDC45-like protein Miro PF08477.8 KEP60566.1 - 0.15 12.5 0.5 59 4.1 0.0 3.2 3 0 0 3 3 3 0 Miro-like protein Nop14 PF04147.7 KEP60566.1 - 0.36 8.7 12.4 0.63 7.8 8.6 1.3 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 KEP60566.1 - 1.3 8.3 11.1 0.11 11.9 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 KEP60566.1 - 9.7 5.3 18.2 0.14 11.4 7.5 1.5 2 0 0 2 2 2 0 SDA1 DUF445 PF04286.7 KEP60568.1 - 4.1 6.8 10.0 0.6 9.5 3.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF445) Sec10 PF07393.6 KEP60569.1 - 0.34 9.0 1.5 1.2 7.1 1.0 1.6 1 1 1 2 2 2 0 Exocyst complex component Sec10 CP12 PF02672.10 KEP60569.1 - 0.89 10.0 9.5 0.34 11.3 3.4 2.4 2 0 0 2 2 2 0 CP12 domain AAA_5 PF07728.9 KEP60570.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribonuc_red_sm PF00268.16 KEP60571.1 - 3.4e-108 360.9 1.7 4.2e-108 360.6 1.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Alg14 PF08660.6 KEP60572.1 - 5.3e-53 179.4 0.0 1e-51 175.2 0.0 2.3 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like MOZ_SAS PF01853.13 KEP60573.1 - 3.9e-76 254.4 0.0 5.7e-76 253.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KEP60573.1 - 2.7e-09 36.5 0.1 1.1e-08 34.6 0.1 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain zf-ribbon_3 PF13248.1 KEP60573.1 - 0.019 14.1 2.8 0.043 13.0 2.0 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Methyltransf_18 PF12847.2 KEP60574.1 - 0.0091 16.5 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KEP60574.1 - 0.039 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Sad1_UNC PF07738.8 KEP60575.1 - 3e-19 69.1 0.0 4.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SAG PF04092.8 KEP60576.1 - 3.2e-40 137.3 30.9 1.2e-13 51.5 1.9 4.2 4 0 0 4 4 4 4 SRS domain IGPS PF00218.16 KEP60578.1 - 2.4e-24 85.7 0.0 5e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 KEP60578.1 - 3.2e-05 22.9 0.0 6.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 KEP60578.1 - 0.046 12.9 0.1 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein PcrB PF01884.12 KEP60578.1 - 0.18 11.0 0.1 0.46 9.6 0.0 1.6 2 0 0 2 2 2 0 PcrB family FAST_1 PF06743.10 KEP60579.1 - 0.074 12.7 3.0 0.51 10.0 0.3 3.1 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 ubiquitin PF00240.18 KEP60582.1 - 0.00024 20.4 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEP60582.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ETF_alpha PF00766.14 KEP60583.1 - 4.1e-30 103.2 0.3 2.4e-29 100.8 0.1 2.3 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 KEP60583.1 - 1.2e-22 80.4 0.2 2.1e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SAG PF04092.8 KEP60585.1 - 8.8e-13 48.7 5.9 1.3e-12 48.2 4.1 1.2 1 0 0 1 1 1 1 SRS domain FUSC_2 PF13515.1 KEP60588.1 - 7.3e-10 38.8 12.7 7.3e-10 38.8 8.8 3.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KEP60588.1 - 0.0011 17.6 4.2 0.0024 16.6 2.9 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter NYD-SP28_assoc PF14775.1 KEP60589.1 - 1.5e-08 34.2 0.9 1.5e-08 34.2 0.6 3.8 4 0 0 4 4 4 1 Sperm tail C-terminal domain DUF3584 PF12128.3 KEP60589.1 - 8.8e-05 20.0 36.3 0.00012 19.6 25.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF285 PF03382.9 KEP60589.1 - 0.083 12.4 0.7 0.87 9.1 0.0 2.2 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Ycf1 PF05758.7 KEP60589.1 - 0.12 10.1 16.3 0.14 9.8 11.3 1.3 1 0 0 1 1 1 0 Ycf1 Ribosomal_S6 PF01250.12 KEP60590.1 - 7.7e-13 48.1 0.0 1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF707 PF05212.7 KEP60590.1 - 0.036 13.1 0.2 0.087 11.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF707) zf-met2 PF12907.2 KEP60592.1 - 3e-15 55.9 4.4 3.9e-15 55.5 3.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KEP60592.1 - 2.8e-09 37.5 4.0 3.9e-09 37.1 2.7 1.2 1 0 0 1 1 1 1 4F5 protein family LRR_6 PF13516.1 KEP60593.1 - 4.5e-06 26.1 6.0 1.5 9.1 0.1 7.6 8 0 0 8 8 8 1 Leucine Rich repeat DUF1752 PF08550.5 KEP60593.1 - 0.079 12.5 0.1 0.62 9.6 0.0 2.4 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) DASH_Dad2 PF08654.5 KEP60596.1 - 0.011 15.6 0.3 0.025 14.5 0.2 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad2 E1-E2_ATPase PF00122.15 KEP60597.1 - 5.3e-52 176.1 5.5 2.8e-51 173.7 0.1 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.21 KEP60597.1 - 1e-26 94.6 0.2 2.3e-26 93.5 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP60597.1 - 7.5e-13 49.0 0.0 1.6e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEP60597.1 - 1.5e-07 30.7 0.0 4.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEP60597.1 - 7.9e-05 22.3 0.1 0.00018 21.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP60597.1 - 0.04 13.8 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Med10 PF09748.4 KEP60598.1 - 9.5e-05 22.2 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Pribosyltran_N PF13793.1 KEP60599.1 - 2.6e-29 101.2 0.0 8.4e-29 99.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEP60599.1 - 5.3e-27 94.7 0.0 8.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEP60599.1 - 0.00035 20.2 0.0 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Herpes_pp85 PF04637.7 KEP60600.1 - 0.04 12.2 0.9 0.058 11.6 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ribosomal_L6 PF00347.18 KEP60601.1 - 4.2e-31 107.2 1.9 3.6e-15 56.2 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 EF-hand_7 PF13499.1 KEP60602.1 - 1.2e-18 66.9 0.2 2.7e-12 46.6 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP60602.1 - 3.9e-15 54.3 0.6 4.6e-08 32.2 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 KEP60602.1 - 3.9e-15 53.9 0.4 4.2e-08 31.9 0.1 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KEP60602.1 - 5.2e-14 51.6 0.1 1.4e-05 24.6 0.0 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KEP60602.1 - 4.7e-08 32.0 3.4 2.4e-05 23.4 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.1 KEP60602.1 - 0.023 14.3 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.4 KEP60602.1 - 0.025 14.5 0.2 0.051 13.6 0.1 1.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region OSCP PF00213.13 KEP60603.1 - 1.7e-48 164.7 1.3 2.1e-48 164.4 0.9 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Birna_VP4 PF01768.11 KEP60603.1 - 0.091 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein IRK PF01007.15 KEP60604.1 - 4.6e-18 65.1 1.4 7e-10 38.2 1.4 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel Ion_trans_2 PF07885.11 KEP60604.1 - 0.0074 15.9 6.5 0.016 14.8 4.5 1.6 1 1 0 1 1 1 1 Ion channel Pax2_C PF12403.3 KEP60605.1 - 0.048 13.3 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Paired-box protein 2 C terminal UPF0047 PF01894.12 KEP60607.1 - 1.1e-23 83.2 0.0 1.9e-12 47.0 0.0 4.1 3 1 0 3 3 3 3 Uncharacterised protein family UPF0047 YjeF_N PF03853.10 KEP60608.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Tmemb_cc2 PF10267.4 KEP60610.1 - 9.1 4.7 5.8 16 3.9 4.0 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein dCMP_cyt_deam_1 PF00383.17 KEP60611.1 - 8.3e-23 79.9 1.9 1.3e-22 79.3 1.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region EF-hand_7 PF13499.1 KEP60613.1 - 2.6e-08 33.8 0.2 0.00017 21.6 0.3 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP60613.1 - 6.2e-05 22.0 0.3 0.34 10.3 0.4 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEP60613.1 - 0.00061 19.4 2.8 9.1 6.4 0.3 4.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 KEP60613.1 - 0.0012 18.3 0.2 2.9 7.5 0.1 3.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 KEP60613.1 - 2 7.9 4.4 1.9 7.9 0.6 2.7 3 0 0 3 3 3 0 EF hand Myb_DNA-binding PF00249.26 KEP60614.1 - 2e-22 78.9 0.3 2.6e-10 40.1 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEP60614.1 - 5e-22 77.7 0.6 1.5e-15 57.0 0.0 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KEP60614.1 - 0.0092 16.0 0.0 0.033 14.3 0.0 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Prenyltrans PF00432.16 KEP60615.1 - 1.9e-39 132.8 15.6 1.3e-09 37.4 0.4 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEP60615.1 - 2.1e-18 66.7 0.4 1.2e-07 32.1 0.0 4.3 2 1 2 4 4 4 4 Prenyltransferase-like Peptidase_S8 PF00082.17 KEP60617.1 - 3e-42 144.7 1.7 5.2e-42 143.9 1.2 1.3 1 0 0 1 1 1 1 Subtilase family Cu-binding_MopE PF11617.3 KEP60617.1 - 0.037 13.8 4.7 0.081 12.7 3.3 1.6 1 0 0 1 1 1 0 Protein metal binding site KIAA1430 PF13879.1 KEP60618.1 - 1e-18 67.5 0.0 2.3e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 KIAA1430 homologue UPF0240 PF06784.6 KEP60618.1 - 0.074 12.7 2.6 0.055 13.1 0.4 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) Pribosyltran PF00156.22 KEP60620.1 - 3.3e-19 68.8 0.0 4.4e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 KEP60620.1 - 0.11 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase UPRTase PF14681.1 KEP60620.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DPM2 PF07297.7 KEP60621.1 - 0.047 13.9 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GAF PF01590.21 KEP60622.1 - 6.5e-25 88.0 1.5 3.9e-16 59.5 0.0 2.6 3 0 0 3 3 3 2 GAF domain GAF_3 PF13492.1 KEP60622.1 - 2e-21 76.4 0.0 5.8e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.1 KEP60622.1 - 1.8e-14 54.4 0.0 5.3e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 GAF domain Rhomboid PF01694.17 KEP60623.1 - 4.3e-29 101.4 14.4 4.3e-29 101.4 10.0 1.7 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.10 KEP60623.1 - 0.03 13.8 3.7 0.067 12.6 2.5 1.8 1 1 0 1 1 1 0 Der1-like family DUF1751 PF08551.5 KEP60623.1 - 3 8.2 7.6 0.59 10.5 0.1 2.7 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) WD40 PF00400.27 KEP60624.1 - 3.4e-18 64.7 5.0 0.00025 20.7 0.3 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat ATG16 PF08614.6 KEP60624.1 - 0.0041 16.9 12.3 0.013 15.3 8.5 1.9 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 KEP60624.1 - 0.18 11.3 11.0 0.31 10.6 7.6 1.3 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 KEP60624.1 - 1 8.2 12.5 1.6 7.5 8.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_11 PF13414.1 KEP60625.1 - 1.2e-08 34.4 1.1 2.6e-07 30.1 0.1 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEP60625.1 - 0.0091 15.8 2.1 6.8 6.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEP60625.1 - 0.051 13.2 0.6 1.5 8.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat GDPD PF03009.12 KEP60626.1 - 3.4e-33 115.2 0.1 3.1e-22 79.3 0.0 3.1 3 0 0 3 3 3 3 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KEP60626.1 - 0.1 12.8 0.6 0.46 10.7 0.0 2.5 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.14 KEP60626.1 - 0.15 11.5 0.1 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain KGG PF10685.4 KEP60626.1 - 2.6 8.1 5.6 22 5.1 0.4 2.4 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif Glycos_transf_2 PF00535.21 KEP60627.1 - 5.4e-22 78.2 0.0 1.1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEP60627.1 - 7.1e-08 32.5 0.0 1.9e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KEP60627.1 - 6e-07 28.8 0.0 1.3e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KEP60627.1 - 4.6e-05 22.8 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase GlcNAc PF11397.3 KEP60627.1 - 0.03 13.4 0.0 0.066 12.3 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) Pkinase PF00069.20 KEP60628.1 - 2.5e-49 167.7 0.0 2.8e-43 147.9 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60628.1 - 6.2e-18 64.8 0.0 3.2e-15 55.8 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase NAP PF00956.13 KEP60629.1 - 2.3e-58 197.2 0.3 2.3e-58 197.2 0.2 2.2 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) SRP14 PF02290.10 KEP60630.1 - 3e-18 65.5 0.0 5.5e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein PA14 PF07691.7 KEP60631.1 - 4.1e-23 81.6 0.0 1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 PA14 domain LCCL PF03815.14 KEP60631.1 - 5.7e-20 71.1 0.1 1.9e-19 69.4 0.1 1.8 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.20 KEP60631.1 - 6.9e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain HSBP1 PF06825.7 KEP60631.1 - 0.024 14.2 0.0 0.47 10.0 0.0 2.3 1 1 0 1 1 1 0 Heat shock factor binding protein 1 Rxt3 PF08642.5 KEP60631.1 - 0.12 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF1759 PF03564.10 KEP60632.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DCX PF03607.12 KEP60633.1 - 7.7e-10 38.2 0.0 3.8e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Doublecortin p25-alpha PF05517.7 KEP60633.1 - 1.8e-08 34.8 0.1 3.1e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 p25-alpha DUF35_N PF12172.3 KEP60633.1 - 0.28 11.1 1.9 0.61 10.0 1.3 1.6 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1042 PF06294.6 KEP60634.1 - 7e-28 97.2 0.0 8e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 KEP60634.1 - 9.2e-20 70.0 0.0 1.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 KEP60634.1 - 1.3e-05 25.1 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF1126 PF06565.7 KEP60635.1 - 7.3e-33 111.7 0.6 9e-13 47.4 0.0 3.4 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 KEP60635.1 - 2.1e-13 50.2 0.1 8.5e-13 48.2 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KEP60635.1 - 4e-12 45.5 4.7 4.5e-11 42.2 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP60635.1 - 7e-10 37.4 6.4 9.4e-07 27.7 0.1 4.3 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 KEP60635.1 - 8.9e-09 34.5 0.9 1.4e-05 24.5 0.0 4.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KEP60635.1 - 0.00021 20.4 5.2 0.0013 18.0 0.0 4.0 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 KEP60635.1 - 0.0021 18.0 0.2 0.0073 16.3 0.1 2.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KEP60635.1 - 0.012 15.5 0.1 0.039 13.8 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain ER_lumen_recept PF00810.13 KEP60637.1 - 2.9e-53 180.3 7.7 4.3e-53 179.7 5.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KEP60637.1 - 0.015 14.8 10.8 0.059 12.9 0.2 4.4 4 1 1 5 5 5 0 PQ loop repeat WES_acyltransf PF03007.11 KEP60638.1 - 0.00066 19.3 6.1 0.018 14.5 2.0 3.1 2 1 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 KEP60638.1 - 0.0029 17.4 0.1 0.008 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) Condensation PF00668.15 KEP60638.1 - 0.045 12.5 0.0 3.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Condensation domain SET PF00856.23 KEP60639.1 - 9.8e-19 68.2 0.2 5.7e-18 65.7 0.0 2.5 2 0 0 2 2 2 1 SET domain SAD_SRA PF02182.12 KEP60639.1 - 4.3e-11 42.3 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 SAD/SRA domain Pre-SET PF05033.11 KEP60639.1 - 3.7e-08 33.5 2.2 1.2e-07 31.9 1.5 2.0 1 0 0 1 1 1 1 Pre-SET motif zf-CSL PF05207.8 KEP60641.1 - 1.1e-11 44.0 2.2 3.9e-11 42.2 1.6 1.9 1 1 0 1 1 1 1 CSL zinc finger Sld5 PF05916.6 KEP60643.1 - 0.00021 21.5 0.1 0.00036 20.8 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein DUF605 PF04652.11 KEP60643.1 - 4.6 6.5 12.5 6 6.1 8.7 1.2 1 0 0 1 1 1 0 Vta1 like zf-CDGSH PF09360.5 KEP60644.1 - 1.7e-09 37.3 0.2 3.6e-09 36.3 0.1 1.6 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type Bax1-I PF01027.15 KEP60645.1 - 2.9e-23 82.5 20.7 3.3e-23 82.3 14.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pyr_redox_2 PF07992.9 KEP60647.1 - 3.1e-16 59.8 0.0 7.4e-06 25.9 0.0 3.8 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEP60647.1 - 3.5e-16 59.3 6.1 5.3e-16 58.7 0.0 3.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEP60647.1 - 6.2e-07 29.6 0.0 0.00019 21.5 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEP60647.1 - 1.3e-05 24.2 0.6 1.6 7.5 0.1 3.6 4 0 0 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEP60647.1 - 0.0002 20.4 0.6 0.28 10.0 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 KEP60647.1 - 0.00034 20.2 0.1 0.00034 20.2 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KEP60647.1 - 0.0035 16.4 1.7 0.52 9.2 0.2 2.4 1 1 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KEP60647.1 - 0.0093 14.8 0.1 0.031 13.1 0.1 1.8 1 1 1 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 KEP60647.1 - 0.017 15.2 1.4 0.48 10.5 0.1 3.2 3 1 1 4 4 4 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KEP60647.1 - 0.019 13.7 4.8 3.4 6.4 0.3 3.3 1 1 2 3 3 3 0 FAD binding domain ApbA PF02558.11 KEP60647.1 - 0.12 11.8 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KEP60647.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KEP60647.1 - 0.2 11.4 4.9 11 5.7 0.2 3.3 2 1 1 3 3 3 0 FAD-NAD(P)-binding WD40 PF00400.27 KEP60649.1 - 6.9e-16 57.4 8.1 1.2e-06 28.1 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat SGL PF08450.7 KEP60649.1 - 0.0075 15.6 0.0 0.6 9.4 0.0 2.8 3 0 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Helicase_C PF00271.26 KEP60651.1 - 3.3e-11 42.9 0.0 1.2e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEP60651.1 - 5.7e-09 35.1 0.0 8.5e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SPOC PF07744.8 KEP60651.1 - 0.064 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 SPOC domain Regulator_TrmB PF11495.3 KEP60651.1 - 0.17 10.8 0.2 1.9 7.4 0.0 2.5 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB SPRY PF00622.23 KEP60654.1 - 0.0041 17.1 1.4 0.011 15.7 0.1 2.3 3 0 0 3 3 3 1 SPRY domain tRNA-synt_1 PF00133.17 KEP60655.1 - 1.8e-105 353.2 0.0 4.1e-45 153.8 0.0 7.7 5 1 0 5 5 5 5 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEP60655.1 - 2.9e-22 79.0 0.0 5.4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEP60655.1 - 1.8e-12 46.6 0.0 7.6e-10 38.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Host_attach PF10116.4 KEP60656.1 - 1.4 9.1 6.1 0.94 9.7 3.4 1.3 1 1 0 1 1 1 0 Protein required for attachment to host cells SufE PF02657.10 KEP60657.1 - 4.1e-23 81.3 0.0 5.4e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Fe-S metabolism associated domain Sec23_trunk PF04811.10 KEP60658.1 - 1.7e-50 171.6 0.0 3.1e-44 151.1 0.0 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 KEP60658.1 - 9.7e-17 61.2 0.0 2.1e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEP60658.1 - 1.2e-16 59.9 4.6 2.2e-16 59.1 3.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 KEP60658.1 - 1.6e-11 43.5 0.1 1.5e-05 24.3 0.0 2.5 1 1 1 2 2 2 2 Sec23/Sec24 helical domain Gelsolin PF00626.17 KEP60658.1 - 3e-05 23.6 0.7 8.2e-05 22.2 0.0 2.1 3 0 0 3 3 3 1 Gelsolin repeat Cyt-b5 PF00173.23 KEP60659.1 - 1.2e-06 28.2 0.0 6.2e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain TPR_11 PF13414.1 KEP60662.1 - 4.5e-12 45.4 6.0 1.8e-07 30.6 0.3 3.5 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KEP60662.1 - 1.4e-09 37.0 7.0 8e-05 22.2 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP60662.1 - 4.1e-09 35.6 2.7 0.021 14.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEP60662.1 - 0.0031 17.3 1.3 0.0031 17.3 0.9 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP60662.1 - 0.0086 15.7 0.7 2 8.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP60662.1 - 0.31 11.7 15.4 0.041 14.5 0.9 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP60662.1 - 0.86 9.5 11.4 0.068 13.1 0.3 3.8 3 2 2 5 5 5 0 Tetratricopeptide repeat Speriolin_C PF15059.1 KEP60664.1 - 0.049 13.6 0.3 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Speriolin C-terminus RAMP4 PF06624.7 KEP60665.1 - 1.4e-24 85.3 0.1 1.5e-24 85.2 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 PP2C PF00481.16 KEP60667.1 - 3.5e-39 134.7 0.0 5.7e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEP60667.1 - 9.9e-05 21.8 0.0 0.00048 19.5 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEP60667.1 - 0.024 14.3 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) ER_lumen_recept PF00810.13 KEP60668.1 - 3.8e-50 170.2 11.7 6e-50 169.5 8.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KEP60668.1 - 0.028 13.9 7.4 0.31 10.6 0.1 3.7 3 1 1 4 4 4 0 PQ loop repeat DUF3021 PF11457.3 KEP60668.1 - 0.076 12.9 6.3 0.054 13.3 3.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Mito_carr PF00153.22 KEP60669.1 - 3.6e-09 36.2 0.0 0.0011 18.5 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF883 PF05957.8 KEP60671.1 - 0.00022 21.5 12.7 0.03 14.7 1.4 2.9 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KEP60671.1 - 0.0016 18.7 14.6 0.75 10.2 1.1 3.1 1 1 1 2 2 2 2 YtxH-like protein Entericidin PF08085.6 KEP60671.1 - 0.0026 17.4 1.5 6.1 6.7 0.1 4.0 3 0 0 3 3 3 1 Entericidin EcnA/B family CAP18_C PF12153.3 KEP60671.1 - 0.11 12.2 0.4 3.2 7.4 0.0 2.9 3 0 0 3 3 3 0 LPS binding domain of CAP18 (C terminal) DUF2059 PF09832.4 KEP60671.1 - 0.17 11.9 2.4 0.62 10.1 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) DUF1805 PF08827.6 KEP60671.1 - 1.4 8.8 4.0 26 4.6 0.1 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF1805) MT0933_antitox PF14013.1 KEP60671.1 - 2.7 8.1 10.5 2.8e+02 1.7 6.3 2.8 1 1 0 1 1 1 0 MT0933-like antitoxin protein Chlorosome_CsmC PF11098.3 KEP60671.1 - 3 7.5 13.2 4.3 7.0 1.7 2.3 1 1 1 2 2 2 0 Chlorosome envelope protein C TMP_2 PF06791.8 KEP60671.1 - 7.5 6.1 17.7 2.1 7.8 9.4 1.8 1 1 1 2 2 2 0 Prophage tail length tape measure protein Tape_meas_lam_C PF09718.5 KEP60671.1 - 8.8 6.3 21.3 9 6.2 4.0 3.7 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF3338 PF11819.3 KEP60672.1 - 0.096 12.1 2.0 1.6 8.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) DUF1664 PF07889.7 KEP60672.1 - 0.15 11.9 1.7 2.9 7.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tape_meas_lam_C PF09718.5 KEP60672.1 - 0.18 11.7 4.9 0.37 10.7 1.0 2.5 1 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.2 KEP60672.1 - 3.4 8.0 11.7 1e+03 0.1 8.1 3.0 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.8 KEP60672.1 - 8.2 6.9 8.8 74 3.8 4.6 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 KEP60673.1 - 2.5e-06 27.1 19.6 0.0007 19.1 7.2 3.6 2 2 1 3 3 3 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 KEP60673.1 - 5e-06 26.8 56.7 0.057 13.8 3.0 8.1 1 1 6 8 8 8 6 Bacterial protein of unknown function (DUF883) Tmemb_cc2 PF10267.4 KEP60673.1 - 4.8e-05 22.1 12.8 4.8e-05 22.1 8.9 2.8 2 1 1 3 3 3 1 Predicted transmembrane and coiled-coil 2 protein YtxH PF12732.2 KEP60673.1 - 1.7 9.0 69.8 2.3e+02 2.2 2.7 8.9 2 1 1 3 3 3 0 YtxH-like protein Senescence PF06911.7 KEP60674.1 - 0.027 14.1 6.3 0.033 13.8 4.4 1.1 1 0 0 1 1 1 0 Senescence-associated protein Hemerythrin PF01814.18 KEP60674.1 - 0.055 13.6 0.1 0.09 12.9 0.1 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF883 PF05957.8 KEP60674.1 - 0.41 11.0 4.7 7.7 6.9 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LRR_6 PF13516.1 KEP60675.1 - 0.036 14.1 0.1 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 Leucine Rich repeat Atg14 PF10186.4 KEP60678.1 - 5.9 5.7 8.6 8.2 5.2 6.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pneumo_phosprot PF02478.11 KEP60680.1 - 0.023 14.2 9.4 0.034 13.6 6.5 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein TFIIA PF03153.8 KEP60680.1 - 0.024 14.5 2.7 0.029 14.2 1.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 KEP60680.1 - 0.039 12.2 2.2 0.04 12.2 1.5 1.1 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 KEP60680.1 - 0.62 8.6 19.1 0.057 12.0 10.3 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein Pex14_N PF04695.8 KEP60680.1 - 0.98 9.4 11.6 1.1 9.3 6.8 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSP1_C PF07462.6 KEP60680.1 - 2.1 6.6 10.7 2.8 6.2 7.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus HEAT PF02985.17 KEP60681.1 - 5e-09 35.4 9.0 0.28 11.3 0.1 5.1 4 0 0 4 4 4 4 HEAT repeat Condensin2nSMC PF12422.3 KEP60681.1 - 3.9e-05 23.4 0.0 0.00058 19.6 0.0 2.3 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit M11L PF11099.3 KEP60681.1 - 0.027 14.2 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Apoptosis regulator M11L like OPA3 PF07047.7 KEP60682.1 - 1e-08 34.9 0.0 0.00017 21.3 0.0 2.1 2 0 0 2 2 2 2 Optic atrophy 3 protein (OPA3) Macoilin PF09726.4 KEP60682.1 - 0.0075 14.6 10.0 0.01 14.1 6.9 1.2 1 0 0 1 1 1 1 Transmembrane protein DUF4551 PF15087.1 KEP60682.1 - 4.3 5.5 7.9 6.2 5.0 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Desulfoferrodox PF01880.13 KEP60683.1 - 0.04 14.1 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Desulfoferrodoxin Mago_nashi PF02792.9 KEP60683.1 - 0.07 12.8 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Mago nashi protein Dispanin PF04505.7 KEP60683.1 - 0.082 12.4 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Rad9 PF04139.8 KEP60685.1 - 3.6e-16 59.0 0.0 2.8e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 Rad9 PCNA_N PF00705.13 KEP60685.1 - 0.25 10.8 0.0 0.47 9.9 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Herpes_IE68 PF02479.11 KEP60687.1 - 0.06 12.5 0.1 0.14 11.3 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus immediate early protein EGF PF00008.22 KEP60688.1 - 2.7e-17 62.3 240.6 0.0016 18.3 5.0 23.8 22 3 1 23 23 23 17 EGF-like domain cEGF PF12662.2 KEP60688.1 - 4.6e-17 61.3 197.3 0.0013 18.3 0.3 22.2 21 1 0 21 21 21 14 Complement Clr-like EGF-like EGF_3 PF12947.2 KEP60688.1 - 7.8e-16 57.7 207.4 1.1e-05 25.2 4.2 21.5 21 0 0 21 21 21 14 EGF domain FXa_inhibition PF14670.1 KEP60688.1 - 1.9e-09 37.4 262.4 0.0094 16.0 3.0 21.3 17 4 4 21 21 21 16 Coagulation Factor Xa inhibitory site Plasmod_Pvs28 PF06247.6 KEP60688.1 - 0.005 16.4 23.9 0.005 16.4 16.5 10.5 1 1 8 9 9 9 6 Plasmodium ookinete surface protein Pvs28 MMR_HSR1 PF01926.18 KEP60689.1 - 1.2e-16 60.6 0.0 3.8e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEP60689.1 - 0.02 14.6 1.8 2.4 7.9 0.0 3.2 4 0 0 4 4 4 0 Dynamin family FeoB_N PF02421.13 KEP60689.1 - 0.074 12.3 0.1 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Thioredoxin PF00085.15 KEP60690.1 - 1.1e-17 63.6 0.0 2.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEP60690.1 - 0.0003 20.9 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEP60690.1 - 0.0028 17.6 0.1 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 KEP60690.1 - 0.0039 17.2 0.0 0.0095 16.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KEP60690.1 - 0.012 15.1 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.16 KEP60690.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family DSBA PF01323.15 KEP60690.1 - 0.04 13.4 0.1 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain TPR_19 PF14559.1 KEP60692.1 - 6e-11 42.5 6.4 0.0046 17.2 0.0 6.4 5 2 2 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KEP60692.1 - 1e-07 31.9 25.1 0.032 14.3 0.2 6.4 4 2 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KEP60692.1 - 1.6e-05 24.4 18.8 0.1 12.2 0.1 6.4 7 0 0 7 7 7 2 TPR repeat TPR_4 PF07721.9 KEP60692.1 - 0.0001 22.3 1.2 0.7 10.4 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP60692.1 - 0.0011 19.6 12.2 0.18 12.5 0.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP60692.1 - 0.0016 18.0 0.5 17 5.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP60692.1 - 0.0084 16.0 18.3 0.14 12.1 0.0 6.4 7 1 1 8 8 7 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 KEP60692.1 - 0.04 14.0 0.2 2.7 8.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_1 PF00515.23 KEP60692.1 - 0.057 13.0 15.7 0.35 10.5 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEP60692.1 - 0.072 13.0 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 KEP60692.1 - 0.1 12.6 1.1 21 5.3 0.0 4.6 5 0 0 5 5 4 0 PPR repeat TPR_14 PF13428.1 KEP60692.1 - 0.13 12.9 12.7 69 4.4 0.0 6.6 6 2 1 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP60692.1 - 0.31 11.0 0.1 0.31 11.0 0.1 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP60692.1 - 0.33 11.4 15.2 5.4 7.7 0.0 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEP60692.1 - 2.4 8.1 9.2 26 4.9 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEP60692.1 - 4.8 7.1 11.7 5.3 6.9 0.2 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.2 KEP60693.1 - 8.7e-45 150.9 0.2 1.3e-16 60.7 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEP60693.1 - 9.8e-29 97.7 3.7 0.00011 21.7 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KEP60693.1 - 2.1e-25 88.5 5.3 2.5e-08 34.2 0.1 4.7 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP60693.1 - 4.7e-19 66.5 1.5 0.092 13.0 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeat RNA_GG_bind PF10258.4 KEP60693.1 - 4e-18 64.9 0.5 7.9e-18 63.9 0.4 1.5 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_5 PF13857.1 KEP60693.1 - 9.2e-16 57.5 8.6 1e-05 25.5 0.4 5.5 4 1 2 6 6 6 5 Ankyrin repeats (many copies) B9-C2 PF07162.6 KEP60694.1 - 2.9e-29 102.0 0.3 3.6e-29 101.6 0.2 1.4 1 1 0 1 1 1 1 Ciliary basal body-associated, B9 protein Tau95 PF09734.4 KEP60695.1 - 6.8e-46 157.0 0.0 1.3e-45 156.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit zf-DHHC PF01529.15 KEP60696.1 - 2.9e-37 127.7 8.6 2.9e-37 127.7 5.9 2.6 3 0 0 3 3 3 1 DHHC palmitoyltransferase Neur_chan_memb PF02932.11 KEP60696.1 - 8.3e-06 25.8 0.3 1.5e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 KEP60696.1 - 0.00026 18.8 0.0 0.00032 18.6 0.0 1.1 1 0 0 1 1 1 1 Ycf1 DUF2201_N PF13203.1 KEP60696.1 - 0.00032 19.9 2.8 0.00059 19.1 1.9 1.4 1 0 0 1 1 1 1 Putative metallopeptidase domain DUF1510 PF07423.6 KEP60696.1 - 0.0014 18.0 6.5 0.0031 16.9 4.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) PsbN PF02468.10 KEP60696.1 - 2.3 7.8 7.2 0.22 11.1 1.3 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) CDC45 PF02724.9 KEP60696.1 - 3.9 5.3 13.3 6 4.7 9.2 1.4 1 0 0 1 1 1 0 CDC45-like protein EF-hand_1 PF00036.27 KEP60697.1 - 4e-09 35.1 0.2 0.00036 19.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KEP60697.1 - 1.6e-08 33.7 0.2 0.0033 17.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KEP60697.1 - 1.9e-07 31.0 1.5 7.1e-07 29.2 1.0 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEP60697.1 - 1.8e-06 26.9 0.0 0.0021 17.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KEP60697.1 - 2.6e-05 23.7 1.2 0.00025 20.5 0.2 2.2 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEP60697.1 - 0.0009 19.2 0.1 0.0011 18.9 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Methyltransf_23 PF13489.1 KEP60698.1 - 9.1e-15 54.7 0.0 1.3e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP60698.1 - 1.2e-14 54.5 0.0 2.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEP60698.1 - 6.3e-14 51.6 0.0 1.4e-13 50.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KEP60698.1 - 9.4e-09 35.0 0.0 1.7e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP60698.1 - 1.1e-07 32.1 0.0 2.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP60698.1 - 1.2e-05 25.5 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP60698.1 - 4.2e-05 24.0 0.0 9.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L9_N PF01281.14 KEP60698.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain DUF938 PF06080.7 KEP60698.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_29 PF03141.11 KEP60698.1 - 0.055 11.7 0.0 0.067 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 KEP60698.1 - 0.066 11.8 0.0 0.29 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) tRNA_edit PF04073.10 KEP60699.1 - 4.8e-09 36.1 0.2 4.3e-08 33.0 0.1 2.0 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain YgbB PF02542.11 KEP60700.1 - 1e-45 155.4 0.0 1.9e-40 138.2 0.0 2.1 2 0 0 2 2 2 2 YgbB family Pkinase PF00069.20 KEP60703.1 - 4.4e-67 225.9 0.0 5.6e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60703.1 - 3.3e-31 108.2 0.0 4.3e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP60703.1 - 1.6e-05 23.9 0.0 3.4e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEP60703.1 - 6.5e-05 22.0 0.1 0.00022 20.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP60703.1 - 0.00045 20.0 0.3 0.00045 20.0 0.2 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEP60703.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KEP60703.1 - 0.077 12.3 0.2 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 KEP60703.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Antimicrobial21 PF14861.1 KEP60704.1 - 0.085 12.3 2.1 7 6.2 0.0 2.8 3 0 0 3 3 3 0 Plant antimicrobial peptide TIL PF01826.12 KEP60704.1 - 0.56 10.3 9.3 1.2 9.3 0.8 3.0 3 0 0 3 3 3 0 Trypsin Inhibitor like cysteine rich domain tRNA_int_endo PF01974.12 KEP60705.1 - 4.3e-09 36.0 0.1 5.9e-08 32.4 0.1 2.3 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RPAP2_Rtr1 PF04181.8 KEP60707.1 - 1.6e-10 40.9 0.8 4.3e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Rtr1/RPAP2 family Abhydrolase_3 PF07859.8 KEP60708.1 - 3.9e-32 111.5 0.0 1.1e-26 93.7 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KEP60708.1 - 2.1e-10 39.7 0.0 3.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KEP60708.1 - 2.7e-09 36.9 0.0 1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KEP60708.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cript PF10235.4 KEP60709.1 - 1.4e-15 57.3 7.6 1.4e-15 57.3 5.3 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT Peptidase_C74 PF12387.3 KEP60709.1 - 0.01 15.0 2.5 0.0096 15.1 1.7 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase DZR PF12773.2 KEP60709.1 - 0.058 13.2 13.8 0.054 13.3 5.5 2.5 1 1 1 2 2 2 0 Double zinc ribbon Gin PF10764.4 KEP60709.1 - 0.12 12.0 4.5 0.43 10.3 0.1 2.9 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin DiS_P_DiS PF06750.8 KEP60709.1 - 0.25 11.1 9.4 0.11 12.2 3.4 2.4 1 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF2039 PF10217.4 KEP60709.1 - 0.52 10.3 11.2 0.081 12.9 3.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-C3HC4_3 PF13920.1 KEP60709.1 - 0.74 9.5 13.3 5.3 6.7 4.2 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 KEP60709.1 - 0.85 9.1 0.1 0.85 9.1 0.1 3.5 3 1 1 4 4 4 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 KEP60709.1 - 4.3 7.2 11.4 12 5.7 4.3 2.5 2 1 0 2 2 2 0 zinc-ribbons Sar8_2 PF03058.9 KEP60709.1 - 5.8 7.3 7.3 9 6.7 5.1 1.6 1 1 0 1 1 1 0 Sar8.2 family EF-hand_1 PF00036.27 KEP60710.1 - 3.5e-30 100.9 7.8 2.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP60710.1 - 1.7e-29 101.7 9.7 1.2e-14 54.1 1.3 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KEP60710.1 - 2e-24 83.2 7.7 3.1e-09 35.9 0.0 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KEP60710.1 - 2.7e-24 84.5 11.0 4e-11 42.3 0.3 3.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KEP60710.1 - 8.8e-20 69.0 12.1 1.6e-06 27.1 0.0 4.5 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KEP60710.1 - 4.6e-11 42.4 0.1 2e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEP60710.1 - 8.8e-06 25.4 2.3 0.04 13.6 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEP60710.1 - 0.0026 17.7 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 KEP60710.1 - 0.0044 16.6 0.0 0.11 11.9 0.0 2.3 2 1 0 2 2 2 1 Caleosin related protein TerB PF05099.8 KEP60710.1 - 0.011 15.4 0.1 3.1 7.5 0.0 3.0 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF3008 PF11450.3 KEP60710.1 - 0.012 15.7 1.1 0.025 14.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Toprim_2 PF13155.1 KEP60710.1 - 0.016 15.5 0.1 0.82 10.0 0.0 2.3 1 1 1 2 2 2 0 Toprim-like IF2_N PF04760.10 KEP60710.1 - 0.059 13.0 1.6 13 5.4 0.1 3.1 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Acetyltransf_11 PF13720.1 KEP60710.1 - 0.092 12.9 0.0 1.1 9.4 0.0 2.3 1 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF1257 PF06868.6 KEP60710.1 - 0.094 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) DDRGK PF09756.4 KEP60711.1 - 5.3e-47 159.6 26.0 1.5e-46 158.1 18.0 1.8 1 1 0 1 1 1 1 DDRGK domain Ly49 PF08391.5 KEP60711.1 - 0.13 12.3 0.4 4.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region CDC27 PF09507.5 KEP60711.1 - 2.7 7.1 14.1 4.9 6.2 9.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BTV_NS2 PF04514.7 KEP60711.1 - 5 5.9 14.3 9.1 5.0 9.9 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AP2 PF00847.15 KEP60715.1 - 0.00042 20.3 0.2 0.00098 19.2 0.1 1.7 1 0 0 1 1 1 1 AP2 domain DUF2328 PF10090.4 KEP60715.1 - 0.23 10.6 1.1 0.35 10.0 0.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2328) TFIIS_C PF01096.13 KEP60716.1 - 5.2e-15 54.7 2.3 5.2e-15 54.7 1.6 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.1 KEP60716.1 - 0.025 13.7 7.2 0.06 12.5 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KEP60716.1 - 0.4 10.6 8.6 9.5 6.2 0.1 4.0 4 0 0 4 4 4 0 Zinc ribbon domain Lar_restr_allev PF14354.1 KEP60716.1 - 4.1 7.7 7.6 6.5 7.1 2.1 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Baculo_LEF5_C PF11792.3 KEP60716.1 - 7.4 6.0 9.4 0.47 9.8 2.5 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Ribosomal_60s PF00428.14 KEP60717.1 - 0.0071 16.7 1.0 0.0088 16.4 0.7 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF810 PF05664.6 KEP60718.1 - 1.4 7.1 1.0 2.1 6.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF810) CBP PF12192.3 KEP60720.1 - 0.041 13.8 2.5 0.041 13.8 1.7 2.1 2 0 0 2 2 2 0 Fungal calcium binding protein Sad1_UNC PF07738.8 KEP60721.1 - 2.4e-23 82.3 0.0 1.6e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Tropomyosin_1 PF12718.2 KEP60721.1 - 0.0019 18.0 7.0 0.0019 18.0 4.9 2.5 2 1 1 3 3 2 1 Tropomyosin like CALCOCO1 PF07888.6 KEP60721.1 - 0.022 13.0 15.8 0.033 12.4 11.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 KEP60721.1 - 0.023 15.0 2.2 0.023 15.0 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Myc_N PF01056.13 KEP60721.1 - 0.049 12.8 4.8 0.095 11.8 3.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF4407 PF14362.1 KEP60721.1 - 0.12 11.2 11.4 0.22 10.4 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2317 PF10079.4 KEP60721.1 - 0.28 9.7 13.1 0.86 8.1 8.1 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) HemX PF04375.9 KEP60721.1 - 0.3 9.6 9.3 0.55 8.7 6.5 1.3 1 0 0 1 1 1 0 HemX Apolipoprotein PF01442.13 KEP60721.1 - 0.37 10.2 25.5 0.98 8.8 17.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Hemerythrin PF01814.18 KEP60721.1 - 0.49 10.5 10.4 1.3 9.1 7.2 1.7 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain CENP-B_dimeris PF09026.5 KEP60721.1 - 0.61 10.3 10.4 1.9 8.7 7.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KEP60721.1 - 0.64 9.5 8.8 1.5 8.3 6.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin Spore_III_AB PF09548.5 KEP60721.1 - 0.97 9.1 8.1 1.1 9.0 4.7 1.7 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF445 PF04286.7 KEP60721.1 - 1.5 8.2 7.8 2.3 7.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PBP1_TM PF14812.1 KEP60721.1 - 1.6 9.0 10.1 0.13 12.5 1.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMPIT PF07851.8 KEP60721.1 - 2.2 7.2 7.5 3.8 6.4 5.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein TBPIP PF07106.8 KEP60721.1 - 2.4 7.6 16.1 5.8 6.4 4.4 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 KEP60721.1 - 3.2 7.5 6.1 11 5.8 0.2 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.10 KEP60721.1 - 4 6.5 10.2 6.4 5.8 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit XhlA PF10779.4 KEP60721.1 - 4.1 7.4 11.4 0.093 12.6 1.0 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Mitofilin PF09731.4 KEP60721.1 - 4.7 5.7 24.2 0.2 10.2 12.8 1.5 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Atg14 PF10186.4 KEP60721.1 - 5.1 5.9 19.9 3.1 6.6 7.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KEP60721.1 - 5.3 6.5 19.5 0.055 12.9 1.7 3.4 2 1 1 3 3 3 0 Septum formation initiator Syntaxin PF00804.20 KEP60722.1 - 0.02 15.0 6.1 1 9.5 1.0 2.8 1 1 1 2 2 2 0 Syntaxin TPR_MLP1_2 PF07926.7 KEP60722.1 - 0.042 13.5 0.7 0.21 11.3 0.5 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Med9 PF07544.8 KEP60722.1 - 0.14 11.9 2.3 0.66 9.7 0.1 3.2 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Apolipoprotein PF01442.13 KEP60722.1 - 0.32 10.4 17.3 0.19 11.2 5.7 2.7 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KEP60722.1 - 0.85 9.4 7.4 8.5 6.1 0.3 3.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 KEP60722.1 - 4.4 7.2 6.6 50 3.8 0.2 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) LRR_4 PF12799.2 KEP60723.1 - 6.7e-14 51.1 3.9 6.9e-07 28.7 0.2 4.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP60723.1 - 4.6e-10 39.0 3.1 2.3e-09 36.8 0.9 2.7 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KEP60723.1 - 2.4e-05 23.7 3.5 0.45 10.7 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 KEP60723.1 - 0.00052 19.8 3.6 1.7 8.9 0.7 4.8 4 1 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 KEP60723.1 - 0.001 18.8 4.5 16 6.2 0.0 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 KEP60723.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.3 1 1 0 1 1 1 1 Leucine-rich repeat PH PF00169.24 KEP60724.1 - 2.3e-05 24.5 0.7 5e-05 23.4 0.5 1.7 1 1 0 1 1 1 1 PH domain DUF4349 PF14257.1 KEP60724.1 - 0.38 9.9 4.9 0.64 9.2 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Ribosomal_60s PF00428.14 KEP60724.1 - 2.4 8.5 7.7 4.1 7.8 4.6 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ax_dynein_light PF10211.4 KEP60725.1 - 1.2e-71 240.4 12.7 1.5e-71 240.1 8.8 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain Tropomyosin_1 PF12718.2 KEP60725.1 - 0.0002 21.2 11.3 0.00039 20.2 7.8 1.5 1 0 0 1 1 1 1 Tropomyosin like Allexi_40kDa PF05549.6 KEP60725.1 - 0.0051 16.1 2.0 0.0094 15.2 1.4 1.5 1 0 0 1 1 1 1 Allexivirus 40kDa protein Poty_PP PF08440.5 KEP60725.1 - 0.049 12.6 4.1 0.067 12.2 2.8 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein Fib_alpha PF08702.5 KEP60725.1 - 0.12 12.4 8.9 0.18 11.9 4.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 KEP60725.1 - 0.2 10.0 7.2 0.29 9.5 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GAS PF13851.1 KEP60725.1 - 0.33 10.1 14.9 0.65 9.1 10.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.6 KEP60725.1 - 0.37 11.2 11.0 0.68 10.3 5.2 2.5 2 1 1 3 3 2 0 Syntaxin 6, N-terminal CPSF100_C PF13299.1 KEP60725.1 - 0.37 10.9 5.5 2.8 8.1 3.8 2.2 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RasGAP_C PF03836.10 KEP60725.1 - 0.55 9.9 12.2 0.95 9.1 5.9 2.3 1 1 1 2 2 2 0 RasGAP C-terminus Atg14 PF10186.4 KEP60725.1 - 0.59 9.0 13.6 0.75 8.6 9.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YlbD_coat PF14071.1 KEP60725.1 - 0.63 10.1 8.0 2.3 8.2 5.6 1.9 1 1 0 1 1 1 0 Putative coat protein ApoO PF09769.4 KEP60725.1 - 0.66 9.6 2.9 1.4 8.6 2.0 1.6 1 1 0 1 1 1 0 Apolipoprotein O APG6 PF04111.7 KEP60725.1 - 0.73 8.8 9.7 1.4 7.9 6.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1825 PF08855.5 KEP60725.1 - 1.4 8.9 7.8 13 5.8 5.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) OmpH PF03938.9 KEP60725.1 - 1.9 8.4 15.5 50 3.7 10.1 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF2681 PF10883.3 KEP60725.1 - 5.7 7.2 10.4 2.1 8.6 4.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DivIC PF04977.10 KEP60725.1 - 5.9 6.4 15.3 2.9 7.4 2.6 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF724 PF05266.9 KEP60725.1 - 7.1 6.2 15.7 1.8 8.1 8.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 KEP60725.1 - 9.6 6.1 18.6 1 9.2 2.2 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Ribosomal_L28e PF01778.12 KEP60726.1 - 2e-27 95.9 1.5 2e-27 95.9 1.0 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KEP60726.1 - 4e-09 36.4 36.2 4e-09 36.4 25.1 3.5 4 1 0 4 4 4 1 Mak16 protein C-terminal region TP_methylase PF00590.15 KEP60730.1 - 1.2e-20 74.1 0.0 1.9e-20 73.5 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pam16 PF03656.8 KEP60731.1 - 6.2e-13 48.6 0.2 7.1e-13 48.4 0.1 1.0 1 0 0 1 1 1 1 Pam16 Mito_carr PF00153.22 KEP60732.1 - 2.1e-68 226.0 3.6 1.8e-24 85.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydrolase_like2 PF13246.1 KEP60732.1 - 0.054 13.4 0.1 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Cyclin_N PF00134.18 KEP60734.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain C2 PF00168.25 KEP60735.1 - 2e-19 69.2 0.1 3.1e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 C2 domain DNA_pol_viral_N PF00242.12 KEP60735.1 - 0.071 12.1 0.5 0.17 10.8 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain TPR_MLP1_2 PF07926.7 KEP60736.1 - 0.0049 16.6 17.2 0.0049 16.6 11.9 4.7 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein Hemerythrin PF01814.18 KEP60736.1 - 0.011 15.8 6.7 0.011 15.8 4.7 4.2 3 2 1 4 4 4 0 Hemerythrin HHE cation binding domain Filament PF00038.16 KEP60736.1 - 0.078 12.4 64.1 0.058 12.8 16.3 4.1 2 1 2 4 4 4 0 Intermediate filament protein EST1 PF10374.4 KEP60736.1 - 0.5 10.3 5.8 0.86 9.6 1.4 2.9 2 1 0 3 3 3 0 Telomerase activating protein Est1 Baculo_PEP_C PF04513.7 KEP60736.1 - 2.9 7.6 16.5 0.71 9.6 3.4 3.4 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.13 KEP60736.1 - 2.9 7.6 22.2 0.58 9.9 0.2 5.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper TPT PF03151.11 KEP60737.1 - 0.018 14.7 1.0 0.018 14.7 0.7 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family Dynein_heavy PF03028.10 KEP60738.1 - 8.5e-211 701.7 0.0 2.2e-208 693.7 0.0 2.7 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 KEP60738.1 - 4.6e-68 229.0 0.0 8.4e-68 228.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEP60738.1 - 1.2e-52 178.0 0.1 3.1e-52 176.7 0.0 1.7 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 KEP60738.1 - 3.8e-39 134.4 7.0 3.8e-39 134.4 4.8 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor ACR_tran PF00873.14 KEP60738.1 - 0.18 9.1 1.1 0.32 8.3 0.8 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF4486 PF14858.1 KEP60742.1 - 1.7e-15 56.3 0.4 2.3e-15 55.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) DUF2723 PF11028.3 KEP60743.1 - 0.077 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) DUF948 PF06103.6 KEP60743.1 - 0.16 11.8 1.1 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PAP_assoc PF03828.14 KEP60744.1 - 5.4e-06 26.2 0.0 1.4e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEP60744.1 - 0.00011 22.3 0.0 0.00041 20.6 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyltransferase domain DUF3446 PF11928.3 KEP60744.1 - 2.6 8.3 17.4 6.4 7.0 8.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DnaJ PF00226.26 KEP60745.1 - 1.4e-10 40.7 0.0 4.7e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Ank_3 PF13606.1 KEP60745.1 - 0.13 12.5 0.0 0.41 11.0 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 KEP60745.1 - 0.22 11.8 0.0 0.72 10.1 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (many copies) TPR_11 PF13414.1 KEP60745.1 - 8.2 6.1 11.2 1.7 8.3 1.2 2.7 2 0 0 2 2 2 0 TPR repeat Lamp PF01299.12 KEP60746.1 - 0.0017 17.6 0.4 0.0028 16.8 0.3 1.3 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Protocadherin PF08374.6 KEP60746.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Herpes_gE PF02480.11 KEP60746.1 - 0.18 10.0 0.2 0.25 9.5 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KEP60746.1 - 1.2 8.5 4.8 2.4 7.5 3.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1182 PF06681.8 KEP60747.1 - 0.022 13.9 1.7 0.022 13.9 1.2 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1182) DUF4191 PF13829.1 KEP60747.1 - 0.032 13.3 0.7 0.054 12.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2231 PF09990.4 KEP60747.1 - 0.91 9.8 6.3 3.1 8.1 2.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) zf-DHHC PF01529.15 KEP60747.1 - 2.6 7.3 7.5 8.7 5.6 5.2 1.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF3995 PF13160.1 KEP60747.1 - 3.4 7.7 12.1 2.4 8.2 4.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) MRAP PF15183.1 KEP60747.1 - 6.1 6.5 5.7 0.47 10.0 0.4 1.8 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family HMG_box PF00505.14 KEP60748.1 - 2.3e-24 85.4 2.4 3.2e-24 84.9 1.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEP60748.1 - 4e-19 68.7 1.8 5.5e-19 68.3 1.2 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KEP60748.1 - 0.012 15.3 1.3 0.025 14.3 0.8 1.6 1 1 0 1 1 1 0 HMG (high mobility group) box 5 KIAA1430 PF13879.1 KEP60748.1 - 0.031 14.6 0.2 0.042 14.2 0.1 1.2 1 0 0 1 1 1 0 KIAA1430 homologue Microtub_assoc PF07989.6 KEP60748.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Microtubule associated WD40 PF00400.27 KEP60750.1 - 6.2e-16 57.6 14.8 1.5e-06 27.8 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Solute_trans_a PF03619.11 KEP60751.1 - 7.1e-60 202.6 7.5 3.5e-59 200.3 5.2 1.9 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Kinase-like PF14531.1 KEP60752.1 - 0.00015 20.7 0.0 0.00086 18.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like DEAD PF00270.24 KEP60753.1 - 3.8e-42 143.6 0.0 6.9e-41 139.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP60753.1 - 1.5e-26 92.0 0.1 5e-26 90.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP60753.1 - 6.6e-05 22.8 0.0 0.02 14.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KEP60753.1 - 0.002 18.0 0.4 1.2 9.0 0.0 3.3 3 1 0 3 3 3 1 Helicase C-terminal domain SecA_DEAD PF07517.9 KEP60753.1 - 0.0037 16.6 0.5 0.0088 15.3 0.3 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain FlxA PF14282.1 KEP60753.1 - 0.017 15.0 2.0 0.017 15.0 1.4 1.9 2 0 0 2 2 2 0 FlxA-like protein zf-CCHC PF00098.18 KEP60753.1 - 0.017 14.9 2.8 0.017 14.9 2.0 2.0 2 0 0 2 2 2 0 Zinc knuckle OmpH PF03938.9 KEP60753.1 - 6.3 6.7 16.6 13 5.7 11.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Abhydrolase_5 PF12695.2 KEP60754.1 - 4.6e-13 49.1 0.2 5.9e-09 35.8 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family SAG PF04092.8 KEP60755.1 - 2.2e-17 63.5 11.5 2.9e-12 47.0 3.9 2.4 2 0 0 2 2 2 2 SRS domain SPRY PF00622.23 KEP60755.1 - 0.082 12.9 0.1 2.2 8.3 0.0 2.5 2 1 0 2 2 2 0 SPRY domain Ig_2 PF13895.1 KEP60755.1 - 0.28 11.3 6.7 0.71 10.0 2.5 2.7 2 2 0 2 2 2 0 Immunoglobulin domain DOT1 PF08123.8 KEP60756.1 - 2.8e-05 23.5 0.0 5.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.8 KEP60756.1 - 0.49 9.4 0.0 0.94 8.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-C3HC4_2 PF13923.1 KEP60758.1 - 0.0029 17.6 4.4 0.0029 17.6 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEP60758.1 - 0.042 13.5 3.4 0.089 12.5 2.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEP60758.1 - 4.8 7.1 6.6 1.5 8.7 1.9 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 KEP60760.1 - 5.7e-52 176.4 0.0 7.5e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60760.1 - 1e-26 93.5 0.0 4.1e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEP60760.1 - 0.0073 15.3 0.1 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ASCH PF04266.9 KEP60761.1 - 0.54 10.6 5.8 0.15 12.4 0.7 2.5 2 0 0 2 2 2 0 ASCH domain NAD_Gly3P_dh_N PF01210.18 KEP60762.1 - 5.8e-46 156.0 0.0 1e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KEP60762.1 - 5.9e-42 142.8 0.3 1.2e-41 141.8 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Sigma70_r1_1 PF03979.9 KEP60762.1 - 0.027 14.3 0.2 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Semialdhyde_dh PF01118.19 KEP60762.1 - 0.092 13.0 0.1 0.39 11.0 0.0 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KEP60762.1 - 0.1 13.0 0.1 1.2 9.6 0.1 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3508 PF12018.3 KEP60763.1 - 0.18 10.7 5.2 0.31 10.0 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) S4 PF01479.20 KEP60766.1 - 7.5e-05 22.0 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain MFS_1 PF07690.11 KEP60771.1 - 2.6e-11 42.8 12.4 2.6e-11 42.8 8.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Proteasome PF00227.21 KEP60772.1 - 1.3e-55 187.6 0.2 1.8e-55 187.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEP60772.1 - 4.2e-13 48.3 0.0 7.9e-13 47.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MIF4G_like_2 PF09090.6 KEP60774.1 - 8.3e-11 41.5 0.1 8.3e-11 41.5 0.0 2.3 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.6 KEP60774.1 - 2.2e-05 23.9 0.3 8.4e-05 22.0 0.2 1.9 1 1 0 1 1 1 1 MIF4G like Hist_deacetyl PF00850.14 KEP60775.1 - 6.3e-73 245.7 0.0 6.5e-67 226.0 0.1 2.2 2 0 0 2 2 2 2 Histone deacetylase domain LMBR1 PF04791.11 KEP60775.1 - 0.37 9.3 0.5 0.61 8.6 0.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GST_N_3 PF13417.1 KEP60776.1 - 1.3e-11 44.4 0.0 3.3e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEP60776.1 - 8e-07 28.9 0.0 3.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEP60776.1 - 2.7e-06 27.7 0.0 5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KEP60776.1 - 2.9e-05 23.9 0.1 5.9e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 KEP60776.1 - 0.0009 19.0 0.1 0.0031 17.3 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YjeF_N PF03853.10 KEP60777.1 - 6.1e-38 130.0 0.0 7.8e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Peptidase_C1 PF00112.18 KEP60779.1 - 2.1e-53 181.4 3.1 2.7e-53 181.0 2.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 KEP60779.1 - 0.038 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Peptidase family C1 propeptide Paf1 PF03985.8 KEP60780.1 - 0.016 13.9 0.1 0.016 13.9 0.1 3.5 2 1 1 3 3 3 0 Paf1 Sigma54_CBD PF04963.8 KEP60780.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain DUF566 PF04484.7 KEP60782.1 - 1.4 8.3 11.1 1.5 8.2 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Mito_carr PF00153.22 KEP60783.1 - 4.4e-38 128.8 4.5 4.4e-14 51.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-synt_C PF00137.16 KEP60785.1 - 2.9e-12 46.2 8.7 4.2e-12 45.7 6.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit C TMA7 PF09072.5 KEP60788.1 - 9e-13 48.4 13.3 1.1e-12 48.1 9.2 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 VKOR PF07884.9 KEP60790.1 - 1.8e-23 82.9 10.3 2.4e-23 82.4 7.2 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Bax1-I PF01027.15 KEP60791.1 - 2.6e-39 134.9 22.1 3.4e-39 134.5 15.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CPDase PF07823.6 KEP60792.1 - 9.3e-09 35.0 0.0 0.00052 19.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 KEP60792.1 - 2.9e-05 23.8 0.7 0.00016 21.4 0.5 2.0 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily PBP1_TM PF14812.1 KEP60794.1 - 8.7 6.7 9.8 22 5.4 0.6 3.8 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec63 PF02889.11 KEP60795.1 - 2.1e-112 375.4 0.0 3.9e-62 210.2 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KEP60795.1 - 2.1e-50 170.5 0.0 1.4e-24 86.4 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP60795.1 - 6.9e-16 57.8 0.0 1.6e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEP60795.1 - 7.2e-14 52.0 0.0 9.6e-08 32.0 0.0 3.5 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEP60795.1 - 7.2e-05 22.9 0.0 0.19 11.8 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KEP60795.1 - 0.00015 21.4 0.2 0.49 10.1 0.0 3.4 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 KEP60795.1 - 0.0014 18.8 0.0 2.6 8.2 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEP60795.1 - 0.0016 17.6 0.2 0.72 9.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.16 KEP60795.1 - 0.51 9.5 0.1 7 5.8 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain SecA_DEAD PF07517.9 KEP60795.1 - 0.53 9.5 0.0 2.7 7.1 0.0 2.1 2 0 0 2 2 2 0 SecA DEAD-like domain ABC_membrane PF00664.18 KEP60796.1 - 4.8e-31 108.1 0.1 7.8e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KEP60796.1 - 5.6e-31 107.6 0.0 1.8e-30 106.0 0.0 1.9 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 KEP60796.1 - 0.0002 20.4 0.0 0.00046 19.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KEP60796.1 - 0.00028 21.0 0.3 0.027 14.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KEP60796.1 - 0.0013 18.7 0.0 0.0078 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEP60796.1 - 0.0018 19.1 0.0 0.0065 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP60796.1 - 0.0025 17.8 7.9 0.004 17.1 2.9 2.9 2 1 0 2 2 1 1 AAA ATPase domain G-alpha PF00503.15 KEP60796.1 - 0.0058 15.3 0.1 0.01 14.5 0.1 1.4 1 0 0 1 1 1 1 G-protein alpha subunit DUF258 PF03193.11 KEP60796.1 - 0.0091 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 APS_kinase PF01583.15 KEP60796.1 - 0.01 15.4 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_10 PF12846.2 KEP60796.1 - 0.011 15.1 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 KEP60796.1 - 0.019 14.4 0.1 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KEP60796.1 - 0.023 14.5 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KEP60796.1 - 0.042 13.2 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEP60796.1 - 0.043 13.2 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 KEP60796.1 - 0.05 13.9 0.9 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KEP60796.1 - 0.057 13.2 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_14 PF13173.1 KEP60796.1 - 0.096 12.5 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KEP60796.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DHC_N2 PF08393.8 KEP60797.1 - 3.9e-125 417.5 3.1 7.3e-125 416.6 2.1 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEP60797.1 - 6.9e-89 297.3 0.1 6.9e-89 297.3 0.1 3.0 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 KEP60797.1 - 4.4e-20 71.8 0.0 5.3e-07 29.4 0.0 4.8 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KEP60797.1 - 1.7e-16 60.1 0.3 1.8e-15 56.8 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 KEP60797.1 - 7.8e-10 39.0 0.0 0.064 13.4 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP60797.1 - 1.4e-07 31.7 0.8 0.17 12.0 0.0 4.4 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 KEP60797.1 - 7e-07 28.4 0.6 0.0006 18.8 0.0 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.1 KEP60797.1 - 8.1e-07 28.7 3.7 0.54 10.0 0.0 3.6 3 0 0 3 3 3 3 Part of AAA domain AAA_16 PF13191.1 KEP60797.1 - 3.9e-06 26.9 1.1 0.82 9.6 0.0 5.0 5 0 0 5 5 4 1 AAA ATPase domain AAA_30 PF13604.1 KEP60797.1 - 1.2e-05 25.0 0.9 1.8 8.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF853 PF05872.7 KEP60797.1 - 2.7e-05 22.7 1.2 0.1 10.9 0.0 3.3 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_17 PF13207.1 KEP60797.1 - 3.6e-05 24.5 0.4 0.49 11.2 0.0 3.7 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 KEP60797.1 - 8.5e-05 22.0 0.0 0.17 11.3 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KEP60797.1 - 0.00044 19.4 0.1 0.12 11.5 0.0 3.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEP60797.1 - 0.00073 19.6 0.0 1.1 9.4 0.0 3.6 3 0 0 3 3 3 1 RNA helicase Zeta_toxin PF06414.7 KEP60797.1 - 0.0017 17.4 0.0 0.82 8.7 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin Sigma54_activat PF00158.21 KEP60797.1 - 0.0032 16.9 0.1 4.2 6.8 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.1 KEP60797.1 - 0.0036 17.6 0.1 3 8.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 KEP60797.1 - 0.0063 15.6 0.2 0.025 13.6 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 KEP60797.1 - 0.012 15.0 0.1 7.7 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 KEP60797.1 - 0.013 15.3 0.5 4.8 6.9 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 KEP60797.1 - 0.018 14.8 0.0 8.1 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain PhoH PF02562.11 KEP60797.1 - 0.021 14.0 1.5 4.4 6.4 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein AAA_2 PF07724.9 KEP60797.1 - 0.072 13.0 0.0 24 4.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) DEAD PF00270.24 KEP60797.1 - 0.096 12.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.17 KEP60797.1 - 0.97 8.8 5.4 15 4.9 0.1 3.8 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain VID27 PF08553.5 KEP60798.1 - 3e-55 187.8 0.2 3.8e-55 187.5 0.1 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein Kinase-like PF14531.1 KEP60799.1 - 5.3e-36 124.0 0.0 7.5e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP60799.1 - 7.4e-12 44.9 0.0 5.3e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DUF2909 PF11137.3 KEP60799.1 - 0.003 17.2 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2909) Pkinase_Tyr PF07714.12 KEP60799.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Metallophos_2 PF12850.2 KEP60800.1 - 6.6e-19 68.2 0.0 8.4e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2437 PF10370.4 KEP60800.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) Metallophos PF00149.23 KEP60800.1 - 0.86 8.9 3.7 2.3 7.5 2.6 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase ATP-synt_10 PF05176.9 KEP60801.1 - 0.18 11.0 0.0 13 4.9 0.0 2.1 2 0 0 2 2 2 0 ATP10 protein Radical_SAM PF04055.16 KEP60802.1 - 6.4e-10 39.4 0.0 1.1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KEP60802.1 - 0.0068 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Peptidase_C13 PF01650.13 KEP60803.1 - 1.1e-36 126.4 0.0 1.5e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Methyltransf_18 PF12847.2 KEP60805.1 - 6.7e-09 36.3 0.1 1.7e-08 34.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEP60805.1 - 1.7e-07 30.6 0.5 2.8e-07 29.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KEP60805.1 - 6.2e-07 29.4 0.6 1.9e-06 27.8 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP60805.1 - 1e-06 28.5 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP60805.1 - 1.4e-05 24.7 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEP60805.1 - 2.1e-05 23.9 0.1 3.6e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KEP60805.1 - 2.2e-05 24.8 0.1 0.00035 20.9 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KEP60805.1 - 0.0041 17.1 0.2 0.0072 16.3 0.1 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 KEP60805.1 - 0.0045 15.7 0.1 0.0093 14.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) CMAS PF02353.15 KEP60805.1 - 0.0049 15.9 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KEP60805.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 KEP60805.1 - 0.0099 16.2 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP60805.1 - 0.013 15.9 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KEP60805.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein zf-C2H2_2 PF12756.2 KEP60805.1 - 0.06 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Methyltransf_16 PF10294.4 KEP60805.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 KEP60805.1 - 0.29 10.2 0.0 0.47 9.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB zf-HIT PF04438.11 KEP60807.1 - 3.6e-08 32.8 10.3 6.1e-08 32.1 7.1 1.4 1 0 0 1 1 1 1 HIT zinc finger PH_6 PF15406.1 KEP60808.1 - 0.14 12.2 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2628 PF10947.3 KEP60809.1 - 0.037 13.8 0.9 0.44 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) PhoD PF09423.5 KEP60810.1 - 1.2e-16 60.4 0.0 4.6e-16 58.4 0.0 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase DUF4131 PF13567.1 KEP60810.1 - 0.075 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4083 PF13314.1 KEP60810.1 - 0.2 11.4 1.0 0.52 10.1 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Kinase-like PF14531.1 KEP60812.1 - 3.1e-46 157.6 0.0 4.3e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP60812.1 - 2.2e-18 66.3 0.0 7.8e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60812.1 - 6.2e-07 28.7 0.0 8.7e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MBOAT PF03062.14 KEP60814.1 - 1.7e-20 73.3 30.4 3.2e-13 49.5 9.7 4.5 4 0 0 4 4 4 3 MBOAT, membrane-bound O-acyltransferase family zf-CCHC_5 PF14787.1 KEP60815.1 - 0.013 15.0 0.3 7.6 6.1 0.0 2.7 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Sas10_Utp3 PF04000.10 KEP60817.1 - 5.3e-10 39.3 0.0 8.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pox_Ag35 PF03286.9 KEP60818.1 - 0.11 11.9 1.8 0.17 11.3 1.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 KEP60818.1 - 2.8 6.3 14.9 4 5.7 10.3 1.2 1 0 0 1 1 1 0 Daxx Family DUF4177 PF13783.1 KEP60819.1 - 0.067 12.8 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) Arm PF00514.18 KEP60820.1 - 6.5e-95 308.1 16.6 9.8e-14 50.5 0.0 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEP60820.1 - 2.1e-29 101.6 1.9 5.9e-05 23.2 0.0 6.0 1 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 KEP60820.1 - 5.1e-26 90.4 6.6 3.3e-10 40.1 0.0 6.3 6 1 1 7 7 7 5 HEAT-like repeat HEAT PF02985.17 KEP60820.1 - 2.9e-18 64.2 8.4 6.7e-06 25.7 0.0 8.7 9 1 0 9 9 9 3 HEAT repeat Arm_2 PF04826.8 KEP60820.1 - 1.3e-09 37.5 0.0 0.0015 17.6 0.0 4.0 1 1 3 4 4 4 2 Armadillo-like IBB PF01749.15 KEP60820.1 - 6e-08 32.7 8.2 7.3e-08 32.4 3.7 2.2 2 0 0 2 2 2 1 Importin beta binding domain V-ATPase_H_C PF11698.3 KEP60820.1 - 1e-06 28.6 0.0 0.39 10.6 0.0 4.3 4 0 0 4 4 4 1 V-ATPase subunit H Adaptin_N PF01602.15 KEP60820.1 - 1.5e-05 23.5 0.0 9.2e-05 20.9 0.0 2.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_PBS PF03130.11 KEP60820.1 - 0.00052 20.2 7.7 0.26 11.8 0.1 5.9 6 0 0 6 6 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 KEP60820.1 - 0.0018 16.6 0.1 0.45 8.7 0.0 2.9 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 KEP60820.1 - 0.0076 15.6 0.1 4.1 6.6 0.0 3.6 2 1 2 4 4 4 1 CLASP N terminal RICTOR_V PF14668.1 KEP60820.1 - 0.0089 15.9 5.3 0.95 9.4 0.0 4.3 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Ric8 PF10165.4 KEP60820.1 - 0.013 14.3 0.1 4.2 6.0 0.0 3.1 3 0 0 3 3 3 0 Guanine nucleotide exchange factor synembryn SAE2 PF08573.5 KEP60821.1 - 0.00027 21.5 2.9 0.00027 21.5 2.0 4.8 5 0 0 5 5 5 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Ribosomal_L1 PF00687.16 KEP60822.1 - 7.7e-22 77.7 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Dpy-30 PF05186.8 KEP60823.1 - 0.0022 17.4 3.3 0.97 8.9 0.2 2.4 2 0 0 2 2 2 2 Dpy-30 motif AAA PF00004.24 KEP60825.1 - 1.7e-18 67.0 0.0 2.7e-16 59.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEP60825.1 - 1.2e-07 31.3 2.0 0.00014 21.5 0.3 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 KEP60825.1 - 8e-05 22.7 0.2 0.0065 16.4 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain DUF2075 PF09848.4 KEP60825.1 - 0.00011 21.3 0.0 0.0018 17.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KEP60825.1 - 0.00051 19.9 0.0 0.73 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEP60825.1 - 0.00054 20.2 0.0 0.23 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEP60825.1 - 0.00058 20.0 0.1 0.14 12.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEP60825.1 - 0.0013 19.5 0.0 0.94 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEP60825.1 - 0.0025 17.5 0.1 0.12 12.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEP60825.1 - 0.0058 16.0 0.0 0.023 14.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 KEP60825.1 - 0.0071 16.0 0.2 0.31 10.6 0.0 3.0 2 1 1 3 3 3 1 NACHT domain RuvB_N PF05496.7 KEP60825.1 - 0.0073 15.3 0.1 0.028 13.4 0.0 1.9 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KEP60825.1 - 0.016 14.6 0.0 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KEP60825.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 KEP60825.1 - 0.026 13.5 0.1 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 KEP60825.1 - 0.044 13.1 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KEP60825.1 - 0.068 11.8 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ResIII PF04851.10 KEP60825.1 - 0.093 12.5 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KEP60825.1 - 0.098 12.2 0.0 0.32 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 KEP60825.1 - 0.11 12.1 0.0 7.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 KEP60825.1 - 0.12 11.8 0.0 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 KEP60825.1 - 0.13 11.4 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 KEP60825.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DAP3 PF10236.4 KEP60825.1 - 0.24 10.2 0.0 0.42 9.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Parvo_NS1 PF01057.12 KEP60825.1 - 0.25 10.1 0.0 0.53 9.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Hpr_kinase_C PF07475.7 KEP60825.1 - 0.3 10.3 0.0 0.55 9.5 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain TPR_11 PF13414.1 KEP60827.1 - 1e-69 230.1 34.7 1.2e-18 66.4 0.6 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 KEP60827.1 - 9.5e-57 186.4 36.0 9e-08 31.4 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 KEP60827.1 - 1.2e-46 152.9 32.4 6.1e-06 25.7 0.4 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 KEP60827.1 - 7.6e-25 86.6 23.7 1.1e-11 44.4 0.5 6.6 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 KEP60827.1 - 6.1e-23 80.9 25.2 3.9e-07 30.5 0.5 7.3 5 3 2 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEP60827.1 - 4.1e-21 73.5 11.4 0.037 14.6 0.1 9.0 8 2 2 10 10 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 KEP60827.1 - 1.2e-18 65.3 33.4 0.0099 15.5 1.2 8.7 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 KEP60827.1 - 1.4e-16 60.5 25.7 1.6e-05 25.1 1.6 7.3 5 2 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEP60827.1 - 6.8e-16 57.0 17.6 0.00014 21.7 0.7 9.4 9 2 1 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEP60827.1 - 7.5e-15 54.5 3.7 0.0028 17.4 0.0 6.0 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEP60827.1 - 2.5e-14 51.8 16.6 0.0021 17.7 0.0 8.4 8 1 1 9 9 9 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEP60827.1 - 5.6e-08 32.5 18.7 0.29 11.0 0.1 8.3 7 2 2 9 9 9 3 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 KEP60827.1 - 0.00012 21.0 7.1 0.12 11.1 0.4 3.3 3 0 0 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KEP60827.1 - 0.00012 21.9 12.5 0.44 10.5 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEP60827.1 - 0.001 19.3 28.9 0.32 11.5 0.2 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat DUF3856 PF12968.2 KEP60827.1 - 0.0012 18.7 9.9 2.3 8.0 0.0 5.0 3 3 0 3 3 3 2 Domain of Unknown Function (DUF3856) Hpt PF01627.18 KEP60827.1 - 0.021 14.7 0.7 0.15 12.0 0.5 2.6 1 0 0 1 1 1 0 Hpt domain Coatomer_E PF04733.9 KEP60827.1 - 0.055 12.6 8.1 0.043 12.9 0.7 3.4 2 1 2 4 4 4 0 Coatomer epsilon subunit Adeno_PIX PF03955.9 KEP60827.1 - 5.4 7.5 9.6 1.7 9.1 1.1 3.0 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) RPN7 PF10602.4 KEP60827.1 - 6.4 6.1 26.3 0.099 12.0 1.5 5.3 2 2 3 5 5 5 0 26S proteasome subunit RPN7 PPR_2 PF13041.1 KEP60828.1 - 3.8e-58 193.2 10.6 1.9e-13 50.1 0.0 8.1 1 1 7 8 8 8 8 PPR repeat family PPR PF01535.15 KEP60828.1 - 1.7e-45 149.8 13.0 6.3e-06 25.8 0.0 9.3 9 0 0 9 9 9 7 PPR repeat PPR_1 PF12854.2 KEP60828.1 - 3e-39 132.1 0.1 4.6e-09 35.6 0.0 6.8 6 0 0 6 6 6 6 PPR repeat PPR_3 PF13812.1 KEP60828.1 - 4.5e-37 123.2 3.3 0.00011 22.1 0.0 9.2 9 0 0 9 9 9 6 Pentatricopeptide repeat domain ATP13 PF12921.2 KEP60828.1 - 0.067 12.5 0.1 27 4.1 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ATPase expression MRP-S27 PF10037.4 KEP60828.1 - 0.35 9.7 0.0 1 8.2 0.0 1.7 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 zf-DHHC PF01529.15 KEP60829.1 - 1.1e-40 138.9 8.8 1.1e-40 138.9 6.1 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4013 PF13197.1 KEP60829.1 - 0.11 11.8 8.3 1.2 8.4 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) DUF4173 PF13777.1 KEP60829.1 - 0.54 9.5 5.3 1.1 8.5 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Abhydrolase_6 PF12697.2 KEP60831.1 - 3.2e-09 37.0 4.3 4.1e-08 33.4 2.8 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP60831.1 - 0.0016 18.2 0.0 0.038 13.7 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP60831.1 - 0.0035 16.9 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2422 PF10337.4 KEP60831.1 - 0.24 10.1 3.1 3.1 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) CASP_C PF08172.7 KEP60832.1 - 0.092 11.7 11.8 0.14 11.1 8.2 1.4 1 0 0 1 1 1 0 CASP C terminal Rsa3 PF14615.1 KEP60832.1 - 0.38 10.0 3.6 0.47 9.7 0.0 2.6 3 0 0 3 3 3 0 Ribosome-assembly protein 3 DUF911 PF06023.7 KEP60832.1 - 0.94 8.6 3.6 6.3 5.9 0.1 2.1 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF911) CortBP2 PF09727.4 KEP60832.1 - 8.3 5.8 23.9 0.027 13.9 5.3 2.9 3 0 0 3 3 3 0 Cortactin-binding protein-2 DUF547 PF04784.9 KEP60834.1 - 2.4e-24 85.4 0.0 7e-24 83.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF547 DEP PF00610.16 KEP60834.1 - 6.9e-09 35.3 0.0 1.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glutaredoxin PF00462.19 KEP60834.1 - 0.042 13.8 0.0 0.87 9.6 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin PWWP PF00855.12 KEP60836.1 - 5.7e-09 36.0 0.0 5.7e-09 36.0 0.0 3.3 2 0 0 2 2 2 1 PWWP domain DUF2009 PF09418.5 KEP60837.1 - 4.5e-193 642.1 0.0 2.1e-124 415.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2009) zf-RING_2 PF13639.1 KEP60838.1 - 6.8e-09 35.4 14.6 2.6e-07 30.3 10.2 2.5 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP60838.1 - 4e-05 23.6 0.7 4e-05 23.6 0.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP60838.1 - 9.8e-05 21.9 1.0 9.8e-05 21.9 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP60838.1 - 0.00061 19.7 2.3 0.00061 19.7 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP60838.1 - 0.0039 16.8 0.9 0.0039 16.8 0.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEP60838.1 - 0.011 15.4 0.2 0.024 14.3 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 KEP60838.1 - 0.039 13.8 0.9 0.068 13.0 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KEP60838.1 - 1.3 8.7 8.8 2.9 7.6 2.3 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) GDA1_CD39 PF01150.12 KEP60839.1 - 1.4e-58 198.4 0.0 2.1e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Exo70 PF03081.10 KEP60839.1 - 0.32 9.7 0.0 0.58 8.8 0.0 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Orthopox_A5L PF06193.6 KEP60840.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Seryl_tRNA_N PF02403.17 KEP60840.1 - 0.017 15.1 2.0 0.017 15.1 1.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 KEP60840.1 - 0.14 12.4 1.5 0.39 11.0 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TBPIP PF07106.8 KEP60840.1 - 0.26 10.8 2.4 0.46 10.0 1.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribosomal_S14 PF00253.16 KEP60841.1 - 0.014 14.7 1.3 0.014 14.7 0.9 1.8 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e DUF1279 PF06916.8 KEP60842.1 - 7.6e-11 42.1 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) dsrm PF00035.20 KEP60842.1 - 0.027 15.0 0.0 0.053 14.1 0.0 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding motif zf-HIT PF04438.11 KEP60843.1 - 0.027 14.0 20.5 0.14 11.8 14.2 2.0 1 1 0 1 1 1 0 HIT zinc finger Sec62 PF03839.11 KEP60843.1 - 1.7 8.0 5.0 2.2 7.6 3.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 YEATS PF03366.11 KEP60845.1 - 0.012 15.2 13.6 31 4.3 0.0 7.5 4 3 2 7 7 7 0 YEATS family Senescence_reg PF04520.8 KEP60845.1 - 3.9 7.9 4.4 79 3.7 0.0 3.9 3 2 1 4 4 4 0 Senescence regulator PIG-U PF06728.8 KEP60846.1 - 7.2e-86 288.4 15.3 9e-86 288.1 10.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U UvrD-helicase PF00580.16 KEP60848.1 - 1.1e-34 120.1 12.7 5.3e-29 101.5 0.0 4.7 3 2 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 KEP60848.1 - 6.8e-33 114.5 0.0 4.9e-21 75.5 0.0 4.6 4 1 0 4 4 4 4 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KEP60848.1 - 1.5e-11 43.8 1.4 4.2e-10 39.2 0.7 3.2 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 KEP60848.1 - 4e-08 33.3 0.0 0.00079 19.5 0.0 3.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Slx4 PF09494.5 KEP60849.1 - 8.6e-11 41.4 0.0 1.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Topoisom_bac PF01131.15 KEP60850.1 - 2.4e-73 247.3 0.0 1.4e-30 106.4 0.1 5.3 4 2 0 4 4 4 4 DNA topoisomerase Toprim PF01751.17 KEP60850.1 - 4.7e-12 45.7 0.0 1.4e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.14 KEP60850.1 - 1.2e-09 37.4 0.8 2.7e-09 36.3 0.6 1.6 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger EcsC PF12787.2 KEP60850.1 - 0.48 9.7 0.0 2.4 7.4 0.0 1.9 2 0 0 2 2 2 0 EcsC protein family WD40 PF00400.27 KEP60851.1 - 1.5e-11 43.7 9.5 0.00019 21.1 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3698 PF12479.3 KEP60851.1 - 0.11 12.5 0.5 0.4 10.8 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Metal_resist PF13801.1 KEP60851.1 - 0.19 11.7 9.5 0.19 11.6 5.4 1.9 2 0 0 2 2 2 0 Heavy-metal resistance AAA PF00004.24 KEP60852.1 - 4.7e-40 136.8 0.0 1e-39 135.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP60852.1 - 1e-06 28.9 0.1 0.00011 22.3 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KEP60852.1 - 1.5e-05 24.7 0.1 9.2e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEP60852.1 - 0.00018 22.2 0.1 0.0005 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP60852.1 - 0.00026 21.0 0.0 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KEP60852.1 - 0.0012 18.5 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 KEP60852.1 - 0.002 18.0 0.0 0.0049 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KEP60852.1 - 0.002 17.1 0.0 0.0052 15.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KEP60852.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEP60852.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEP60852.1 - 0.02 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEP60852.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 KEP60852.1 - 0.036 12.9 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KEP60852.1 - 0.047 13.2 0.1 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEP60852.1 - 0.054 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 KEP60852.1 - 0.06 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KEP60852.1 - 0.069 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KEP60852.1 - 0.076 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus T2SE PF00437.15 KEP60852.1 - 0.086 11.7 0.0 0.21 10.4 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KEP60852.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 KEP60852.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain GDA1_CD39 PF01150.12 KEP60854.1 - 1.1e-131 439.4 0.0 1.3e-131 439.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Rad21_Rec8 PF04824.11 KEP60855.1 - 0.0018 17.4 0.0 0.0045 16.1 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KEP60855.1 - 1.7 8.1 3.6 8.3 5.9 0.0 2.9 3 0 0 3 3 3 0 ScpA/B protein AAA_25 PF13481.1 KEP60857.1 - 2.3e-08 33.6 0.2 5.7e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain Rad51 PF08423.6 KEP60857.1 - 8.2e-08 31.4 0.1 0.0053 15.6 0.0 4.0 4 0 0 4 4 4 2 Rad51 AAA_22 PF13401.1 KEP60857.1 - 0.0005 20.2 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEP60857.1 - 0.0022 18.1 0.1 0.0071 16.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP60857.1 - 0.0034 17.3 2.3 0.0059 16.6 0.3 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KEP60857.1 - 0.0038 16.9 0.5 0.014 15.1 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KEP60857.1 - 0.004 17.9 0.2 0.027 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KEP60857.1 - 0.006 15.7 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 KEP60857.1 - 0.0075 16.5 0.4 0.046 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KEP60857.1 - 0.021 14.4 0.0 0.09 12.3 0.0 2.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KEP60857.1 - 0.028 14.5 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase XPG_I PF00867.13 KEP60858.1 - 9.8e-17 60.8 0.0 2e-14 53.4 0.0 2.5 2 0 0 2 2 2 2 XPG I-region XPG_N PF00752.12 KEP60858.1 - 4.7e-15 55.6 0.0 1.9e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 XPG N-terminal domain XPG_I_2 PF12813.2 KEP60858.1 - 0.013 15.0 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 XPG domain containing HHH_2 PF12826.2 KEP60858.1 - 0.023 14.5 0.0 4.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Mito_carr PF00153.22 KEP60859.1 - 4.6e-57 189.7 0.2 7.8e-21 73.5 0.1 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein DUF2730 PF10805.3 KEP60860.1 - 0.38 10.5 2.5 0.62 9.8 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) SNF2_N PF00176.18 KEP60861.1 - 1.7e-17 63.1 0.0 2.7e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KEP60861.1 - 0.013 15.2 0.0 0.28 10.9 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2102 PF09875.4 KEP60862.1 - 0.49 9.9 2.4 7.1 6.2 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) IL12p40_C PF10420.4 KEP60862.1 - 3.4 7.8 9.3 0.59 10.2 0.7 3.5 4 0 0 4 4 4 0 Cytokine interleukin-12p40 C-terminus RabGAP-TBC PF00566.13 KEP60863.1 - 7.3e-22 77.8 0.1 1.4e-21 76.9 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 KEP60863.1 - 2.4e-14 53.1 0.0 3.2e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60863.1 - 3.4e-06 26.3 0.0 1.1e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP60863.1 - 0.00025 20.1 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2161 PF09929.4 KEP60863.1 - 0.66 9.9 2.5 0.61 10.0 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) DUF2305 PF10230.4 KEP60864.1 - 6 6.1 0.0 10 5.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PAT1 PF09770.4 KEP60865.1 - 0.73 7.9 4.5 0.36 9.0 0.1 2.6 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 KEP60866.1 - 6.7 4.2 18.9 7.6 4.0 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein KRAB PF01352.22 KEP60867.1 - 0.018 14.5 0.5 1.5 8.3 0.0 2.6 2 0 0 2 2 2 0 KRAB box Ribosomal_L30 PF00327.15 KEP60868.1 - 0.037 13.6 0.1 0.36 10.4 0.0 2.5 1 1 1 2 2 2 0 Ribosomal protein L30p/L7e Yip1 PF04893.12 KEP60869.1 - 3.4e-16 59.2 5.4 4.5e-16 58.8 3.7 1.2 1 0 0 1 1 1 1 Yip1 domain DUF2964 PF11177.3 KEP60869.1 - 0.055 13.4 0.4 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Methyltransf_26 PF13659.1 KEP60870.1 - 1.2e-08 34.9 0.1 3.7e-07 30.1 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KEP60870.1 - 4.2e-08 32.2 0.0 7.6e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KEP60870.1 - 3.2e-07 30.0 0.1 1e-06 28.3 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP60870.1 - 5.3e-05 23.7 0.0 0.0028 18.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KEP60870.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 KEP60870.1 - 0.0014 18.9 0.1 0.0042 17.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEP60870.1 - 0.01 15.4 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 KEP60870.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.14 KEP60870.1 - 0.14 11.7 0.0 0.54 9.7 0.0 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KEP60870.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 KEP60870.1 - 0.33 9.9 0.0 0.62 9.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase PPR_2 PF13041.1 KEP60871.1 - 2.8e-53 177.6 0.1 3.4e-12 46.1 0.0 9.0 7 2 3 10 10 10 9 PPR repeat family PPR_1 PF12854.2 KEP60871.1 - 9.4e-39 130.5 0.2 3.5e-05 23.2 0.0 10.0 10 0 0 10 10 10 7 PPR repeat PPR_3 PF13812.1 KEP60871.1 - 2.8e-37 123.8 12.2 0.00024 21.1 0.0 12.6 13 0 0 13 13 13 7 Pentatricopeptide repeat domain PPR PF01535.15 KEP60871.1 - 5.7e-35 116.8 6.7 3.5e-05 23.4 0.0 11.9 12 1 0 12 12 12 7 PPR repeat DEAD PF00270.24 KEP60872.1 - 4e-41 140.3 0.5 8.4e-41 139.2 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP60872.1 - 2.6e-27 94.5 0.2 1.1e-26 92.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KEP60872.1 - 7e-05 22.4 0.1 0.00017 21.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KEP60872.1 - 0.00015 21.6 0.1 0.00063 19.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 KEP60872.1 - 0.00042 20.0 0.0 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 Helicase tRNA-synt_1b PF00579.20 KEP60872.1 - 0.00053 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) AAA_30 PF13604.1 KEP60872.1 - 0.00076 19.1 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 KEP60872.1 - 0.002 17.2 0.2 0.0063 15.6 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 KEP60872.1 - 0.056 12.7 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain zf-UBP PF02148.14 KEP60873.1 - 9.5e-17 60.8 7.0 2.6e-16 59.4 4.9 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2183 PF09949.4 KEP60874.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DLIC PF05783.6 KEP60875.1 - 5.8 5.4 2.0 21 3.6 1.4 1.9 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ribosomal_L29 PF00831.18 KEP60876.1 - 4.4e-20 71.1 1.7 4.4e-20 71.1 1.2 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.1 KEP60876.1 - 0.027 14.7 2.0 0.027 14.7 1.4 1.8 2 0 0 2 2 2 0 Snapin/Pallidin Ribosomal_L44 PF00935.14 KEP60876.1 - 0.11 12.5 7.1 0.21 11.6 4.9 1.4 1 0 0 1 1 1 0 Ribosomal protein L44 Spc42p PF11544.3 KEP60876.1 - 0.17 11.8 3.8 0.11 12.4 1.2 1.7 1 1 1 2 2 2 0 Spindle pole body component Spc42p SAC3_GANP PF03399.11 KEP60878.1 - 1e-15 57.8 0.0 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KEP60878.1 - 2.4e-12 46.8 2.6 2.8e-11 43.3 0.2 2.8 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 Rapamycin_bind PF08771.6 KEP60878.1 - 0.037 14.1 0.2 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Rapamycin binding domain PAPS_reduct PF01507.14 KEP60878.1 - 0.22 11.3 1.0 1.2 8.9 0.0 2.4 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.20 KEP60880.1 - 6.1e-29 100.9 0.0 4.2e-10 39.2 0.0 4.3 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60880.1 - 1.2e-09 37.5 0.1 0.00025 20.1 0.1 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KEP60880.1 - 0.65 8.7 0.0 0.97 8.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-DHHC PF01529.15 KEP60881.1 - 3.1e-44 150.4 2.4 3.1e-44 150.4 1.7 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase PfkB PF00294.19 KEP60882.1 - 1.7e-51 175.2 0.4 2.3e-51 174.7 0.3 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DNA_pol_A_exo1 PF01612.15 KEP60883.1 - 7.3e-16 58.1 0.0 3.8e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease Fmp27_WPPW PF10359.4 KEP60884.1 - 0.038 12.4 0.5 0.05 12.0 0.1 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tmemb_cc2 PF10267.4 KEP60885.1 - 7.1 5.0 6.6 1.2 7.6 0.4 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein TPR_2 PF07719.12 KEP60886.1 - 8.2e-10 37.8 6.3 0.0016 18.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEP60886.1 - 1.6e-09 37.2 6.1 7.8e-07 28.6 1.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEP60886.1 - 2.9e-07 29.7 6.5 0.00023 20.6 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEP60886.1 - 2.8e-06 27.8 0.2 0.037 14.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP60886.1 - 3.3e-06 26.8 5.3 7.1e-05 22.5 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEP60886.1 - 4.1e-06 26.6 2.4 0.042 13.7 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KEP60886.1 - 7.8e-05 22.7 8.9 0.0036 17.4 1.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEP60886.1 - 0.00011 22.3 3.3 1 9.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.7 KEP60886.1 - 0.0018 18.0 2.5 0.0044 16.7 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP60886.1 - 0.0045 17.2 4.2 0.0082 16.4 1.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP60886.1 - 0.011 15.3 4.0 5.1 7.1 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat IFRD PF05004.8 KEP60886.1 - 0.038 13.0 3.9 1.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) TPR_17 PF13431.1 KEP60886.1 - 0.061 13.5 0.4 2 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP60886.1 - 0.14 12.8 1.3 23 5.9 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEP60886.1 - 0.15 12.0 0.6 2 8.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Katanin_con80 PF13925.1 KEP60886.1 - 0.16 11.7 3.2 0.8 9.4 0.3 2.2 2 0 0 2 2 2 0 con80 domain of Katanin DUF1469 PF07332.6 KEP60888.1 - 0.033 13.9 0.1 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Vpu PF00558.14 KEP60888.1 - 0.038 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Vpu protein Conotoxin PF02950.12 KEP60888.1 - 0.077 13.8 0.2 0.15 12.8 0.0 1.6 2 0 0 2 2 2 0 Conotoxin DUF2615 PF11027.3 KEP60888.1 - 0.11 12.4 0.2 0.15 11.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Tic20 PF09685.5 KEP60888.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Tic20-like protein DUF1180 PF06679.7 KEP60888.1 - 0.2 11.5 1.9 0.27 11.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Prp18 PF02840.10 KEP60890.1 - 1.3e-59 200.1 1.1 1.3e-59 200.1 0.8 2.1 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KEP60890.1 - 6.1e-13 47.7 0.6 1.5e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like APG12 PF04110.8 KEP60891.1 - 5.3e-20 71.4 0.0 8.4e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RimM PF01782.13 KEP60892.1 - 6.3e-14 51.6 0.2 3.8e-13 49.1 0.0 2.4 3 0 0 3 3 3 1 RimM N-terminal domain zf-C2HC_2 PF13913.1 KEP60892.1 - 0.016 14.8 1.9 0.036 13.7 1.3 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 KEP60892.1 - 0.082 13.2 4.0 0.26 11.7 2.8 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger DUF747 PF05346.6 KEP60893.1 - 4.6e-103 344.7 9.1 5.9e-103 344.4 6.3 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family RRM_1 PF00076.17 KEP60894.1 - 2.3e-37 126.4 0.1 8.5e-19 66.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60894.1 - 6.3e-28 96.5 0.1 6.8e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP60894.1 - 1.3e-14 53.7 0.2 9.8e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 KEP60894.1 - 3e-10 39.7 6.1 6.6e-10 38.6 4.2 1.5 1 0 0 1 1 1 1 WW domain Nup35_RRM PF05172.8 KEP60894.1 - 0.01 15.5 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 KEP60894.1 - 0.016 15.1 0.0 0.061 13.3 0.0 1.9 2 0 0 2 2 2 0 RNA binding domain Nup35_RRM_2 PF14605.1 KEP60894.1 - 0.026 14.3 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MMR1 PF08505.5 KEP60895.1 - 0.05 13.6 3.8 0.067 13.2 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Pox_Ag35 PF03286.9 KEP60895.1 - 0.74 9.3 5.8 1.1 8.8 4.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Menin PF05053.8 KEP60895.1 - 1.2 7.2 4.3 1.4 6.9 3.0 1.1 1 0 0 1 1 1 0 Menin SPC12 PF06645.8 KEP60897.1 - 6.7e-18 64.2 0.4 8.8e-18 63.8 0.3 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Sec62 PF03839.11 KEP60897.1 - 0.033 13.5 0.2 0.033 13.5 0.1 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 Reo_sigmaC PF04582.7 KEP60898.1 - 2.2 7.3 15.0 0.67 9.0 1.4 3.8 4 0 0 4 4 4 0 Reovirus sigma C capsid protein Kelch_3 PF13415.1 KEP60899.1 - 1.3e-24 85.6 5.7 5.5e-08 32.7 0.1 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KEP60899.1 - 3e-18 65.3 7.4 1.9e-05 24.3 0.2 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEP60899.1 - 5.5e-15 54.7 5.5 0.013 15.6 0.0 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KEP60899.1 - 2.3e-09 36.9 4.9 0.14 12.1 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KEP60899.1 - 2.4e-07 30.2 10.7 0.066 12.9 0.1 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KEP60899.1 - 0.0007 19.0 20.0 0.16 11.5 0.3 6.1 5 3 0 5 5 5 3 Kelch motif Nup54 PF13874.1 KEP60899.1 - 0.01 15.4 4.8 0.019 14.6 3.3 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MtrG PF04210.8 KEP60899.1 - 0.18 11.5 2.8 1.5 8.5 0.2 2.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G APG6 PF04111.7 KEP60899.1 - 0.4 9.6 4.8 0.78 8.7 3.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 KEP60899.1 - 1.2 9.4 9.9 0.028 14.7 1.4 2.2 3 0 0 3 3 3 0 AAA domain Sugarporin_N PF11471.3 KEP60899.1 - 4.5 7.0 6.0 2.6 7.7 0.1 2.5 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Rad51 PF08423.6 KEP60900.1 - 1.5e-09 37.1 0.1 0.0028 16.5 0.0 3.1 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.1 KEP60900.1 - 6e-08 32.3 0.1 3.1e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KEP60900.1 - 8.8e-07 28.2 0.0 5.1e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 KaiC RecA PF00154.16 KEP60900.1 - 3e-05 23.2 0.1 0.00062 18.9 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein NACHT PF05729.7 KEP60900.1 - 0.039 13.6 0.0 0.43 10.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 KEP60900.1 - 0.049 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain SNF2_N PF00176.18 KEP60901.1 - 2.3e-74 249.8 0.0 3.9e-74 249.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KEP60901.1 - 7.6e-35 119.1 0.1 2.3e-34 117.6 0.1 1.9 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 KEP60901.1 - 8.3e-16 57.6 0.0 2.1e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP60901.1 - 2.8e-12 46.8 0.2 1.4e-11 44.6 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KEP60901.1 - 1.1e-06 27.7 0.7 1.2e-05 24.2 0.5 2.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_11 PF13086.1 KEP60901.1 - 0.035 13.6 10.0 0.2 11.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.26 KEP60901.1 - 0.037 14.0 0.1 7.1 6.7 0.0 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain HAND PF09110.6 KEP60901.1 - 5.8 7.3 12.0 0.26 11.6 2.2 3.2 2 1 0 2 2 2 0 HAND DUF4547 PF15080.1 KEP60902.1 - 0.13 11.6 0.1 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) SAG PF04092.8 KEP60903.1 - 0.0018 18.6 1.3 0.0028 18.0 0.9 1.3 1 0 0 1 1 1 1 SRS domain TMEM154 PF15102.1 KEP60903.1 - 0.61 9.7 2.2 0.85 9.3 1.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family SAG PF04092.8 KEP60904.1 - 1.1e-25 90.3 2.2 1.4e-25 90.0 1.5 1.1 1 0 0 1 1 1 1 SRS domain RRM_1 PF00076.17 KEP60905.1 - 1.5e-54 181.5 1.6 1.7e-17 62.8 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60905.1 - 4.7e-39 132.2 1.0 4.8e-12 45.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP60905.1 - 1.4e-30 104.9 2.1 4.1e-10 39.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 KEP60905.1 - 2.1e-09 37.0 4.3 4.5e-09 35.9 3.0 1.6 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.6 KEP60905.1 - 6.9e-05 22.7 0.0 0.015 15.2 0.0 3.0 3 0 0 3 3 3 1 RNA binding domain DUF4651 PF15513.1 KEP60905.1 - 0.043 13.2 0.1 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) CS PF04969.11 KEP60906.1 - 2.1e-10 41.0 0.6 3.1e-10 40.4 0.4 1.3 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 KEP60906.1 - 1 9.7 4.8 1.6 9.0 3.3 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Peptidase_C1 PF00112.18 KEP60907.1 - 1.8e-75 253.6 1.0 2.9e-75 252.9 0.7 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 KEP60907.1 - 1.9e-15 56.8 4.2 3.1e-15 56.1 2.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 KEP60907.1 - 0.00014 20.5 4.2 0.0046 15.5 0.9 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Ferric_reduct PF01794.14 KEP60907.1 - 0.053 13.6 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component CAF-1_p150 PF11600.3 KEP60908.1 - 0.003 16.9 21.3 0.003 16.9 14.8 8.1 6 2 0 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal CTD_bind PF04818.8 KEP60910.1 - 1e-15 57.7 0.1 2.1e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-CCHC PF00098.18 KEP60910.1 - 8.2e-08 31.8 2.0 1.5e-07 30.9 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Surp PF01805.15 KEP60910.1 - 7.3e-07 28.7 0.0 1.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Surp module zf-CCHC_4 PF14392.1 KEP60910.1 - 0.062 12.9 0.6 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle FabA PF07977.8 KEP60911.1 - 1.5e-34 118.4 0.0 2e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.14 KEP60911.1 - 0.0056 16.0 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain CPSF73-100_C PF11718.3 KEP60912.1 - 0.018 14.3 0.1 0.038 13.3 0.1 1.5 1 1 1 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Chitin_synth_2 PF03142.10 KEP60913.1 - 2.6 6.3 5.0 3.7 5.8 3.5 1.1 1 0 0 1 1 1 0 Chitin synthase AAA_23 PF13476.1 KEP60914.1 - 0.061 13.6 1.4 0.097 12.9 1.0 1.3 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 KEP60914.1 - 0.26 9.1 6.9 0.36 8.6 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 KEP60914.1 - 0.6 8.4 8.4 0.85 8.0 5.9 1.1 1 0 0 1 1 1 0 AAA domain DUF3402 PF11882.3 KEP60914.1 - 0.69 8.8 4.4 1 8.3 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF641 PF04859.7 KEP60914.1 - 0.74 9.5 7.2 0.72 9.6 4.0 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) GAS PF13851.1 KEP60914.1 - 0.81 8.8 10.4 0.74 8.9 6.4 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 KEP60914.1 - 0.9 8.4 13.5 1.4 7.7 9.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4539 PF15072.1 KEP60915.1 - 3.1e-26 90.8 0.0 4.7e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Dynamin_M PF01031.15 KEP60916.1 - 1.1e-86 290.2 0.0 2.2e-86 289.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KEP60916.1 - 3.3e-48 163.6 0.0 7e-48 162.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KEP60916.1 - 3.5e-23 81.2 0.6 1.6e-22 79.2 0.2 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEP60916.1 - 0.0027 17.6 0.0 0.012 15.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KEP60916.1 - 0.012 15.0 0.2 16 4.9 0.0 4.4 5 2 0 5 5 5 0 FtsK/SpoIIIE family Miro PF08477.8 KEP60916.1 - 0.018 15.5 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 KEP60916.1 - 0.023 15.4 0.0 0.093 13.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEP60916.1 - 0.11 12.4 1.5 2.7 7.9 0.0 3.3 3 2 1 4 4 4 0 AAA ATPase domain RRM_1 PF00076.17 KEP60917.1 - 3.3e-32 109.9 0.8 5.3e-14 51.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP60917.1 - 1.2e-23 82.7 0.7 6.2e-10 38.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60917.1 - 2.5e-23 81.8 0.8 2.6e-12 46.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEP60917.1 - 3.3e-06 26.8 0.7 0.032 14.0 0.0 2.8 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 KEP60917.1 - 3.8e-06 26.5 0.1 0.0081 15.9 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KEP60917.1 - 0.00032 20.3 0.2 0.48 10.2 0.0 3.4 3 0 0 3 3 3 2 Limkain b1 DUF4651 PF15513.1 KEP60917.1 - 0.0025 17.2 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4651) DUF1866 PF08952.6 KEP60917.1 - 0.11 12.0 0.1 6 6.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1866) Nop14 PF04147.7 KEP60918.1 - 1.7 6.4 22.8 1.5 6.6 15.8 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 KEP60918.1 - 2.3 7.7 6.0 2.5 7.5 4.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 KEP60918.1 - 3.1 7.1 11.9 3.3 7.0 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 KEP60918.1 - 7.3 6.0 11.5 8.1 5.8 8.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AAA PF00004.24 KEP60919.1 - 2.1e-92 306.2 0.0 3.1e-45 153.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEP60919.1 - 2.3e-13 49.7 0.0 2.3e-05 23.5 0.0 3.3 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEP60919.1 - 1.2e-12 48.2 0.1 2.7e-06 27.5 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 KEP60919.1 - 2.1e-12 47.1 0.0 1.3e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEP60919.1 - 6.4e-12 45.7 0.4 0.00057 20.0 0.2 4.4 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KEP60919.1 - 6e-11 42.5 0.0 0.00021 21.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEP60919.1 - 1.7e-10 40.7 0.0 1.3e-05 24.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEP60919.1 - 3.1e-10 40.9 0.3 0.003 18.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.7 KEP60919.1 - 6.8e-10 38.3 0.0 0.00019 20.6 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_14 PF13173.1 KEP60919.1 - 1.6e-09 37.7 0.0 0.00068 19.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 KEP60919.1 - 3.6e-08 33.3 0.0 3.3e-05 23.6 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein TIP49 PF06068.8 KEP60919.1 - 8.3e-08 31.3 0.1 0.0017 17.1 0.0 2.8 2 1 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 KEP60919.1 - 8.4e-08 31.8 0.2 0.013 14.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 KEP60919.1 - 1.6e-07 31.1 0.6 0.041 13.5 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.1 KEP60919.1 - 1.9e-07 31.1 0.0 0.018 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KEP60919.1 - 2.1e-07 31.0 0.1 0.04 14.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase ABC_tran PF00005.22 KEP60919.1 - 4.2e-07 30.3 0.1 0.052 13.8 0.0 2.8 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.13 KEP60919.1 - 6.4e-07 29.1 0.0 0.009 15.5 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KEP60919.1 - 3.9e-06 27.2 0.0 0.082 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 KEP60919.1 - 3.9e-06 26.9 0.0 0.023 14.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 KEP60919.1 - 4.9e-06 26.2 0.9 0.17 11.6 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 KEP60919.1 - 6.2e-06 25.5 0.2 0.021 14.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEP60919.1 - 1.1e-05 24.9 0.4 0.017 14.5 0.1 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 KEP60919.1 - 2.6e-05 24.0 0.0 0.47 10.1 0.0 3.6 2 1 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 KEP60919.1 - 3.1e-05 22.9 0.0 0.11 11.3 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.11 KEP60919.1 - 4.9e-05 22.6 0.6 0.31 10.2 0.1 3.0 2 1 0 2 2 2 2 PhoH-like protein DUF815 PF05673.8 KEP60919.1 - 9.8e-05 21.3 0.0 0.28 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) KaiC PF06745.8 KEP60919.1 - 0.00017 20.7 1.1 0.43 9.6 0.0 3.3 2 1 0 3 3 3 1 KaiC Cytidylate_kin2 PF13189.1 KEP60919.1 - 0.00027 20.8 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 KEP60919.1 - 0.00038 20.3 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 2 Shikimate kinase UPF0079 PF02367.12 KEP60919.1 - 0.00054 19.5 0.2 0.27 10.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KEP60919.1 - 0.00058 19.3 5.7 0.68 9.3 0.2 4.1 2 2 1 3 3 3 1 AAA domain NTPase_1 PF03266.10 KEP60919.1 - 0.00069 19.3 0.2 0.39 10.4 0.0 2.9 2 1 1 3 3 3 1 NTPase DUF2075 PF09848.4 KEP60919.1 - 0.0007 18.6 0.0 0.13 11.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 KEP60919.1 - 0.00099 18.7 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KEP60919.1 - 0.0012 18.2 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.12 KEP60919.1 - 0.0029 16.5 0.0 0.95 8.2 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 KEP60919.1 - 0.0031 17.0 0.0 0.89 9.0 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.10 KEP60919.1 - 0.011 15.5 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Vps4_C PF09336.5 KEP60919.1 - 0.012 15.4 0.1 2.8 7.9 0.0 3.1 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain AAA_24 PF13479.1 KEP60919.1 - 0.022 14.3 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KEP60919.1 - 0.023 13.5 0.0 8.7 5.1 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein Rad17 PF03215.10 KEP60919.1 - 0.025 13.2 0.0 4.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein CPT PF07931.7 KEP60919.1 - 0.026 14.1 0.2 0.88 9.1 0.0 3.2 4 0 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 KEP60919.1 - 0.043 13.2 1.6 2.8 7.3 0.0 3.2 4 0 0 4 4 4 0 AAA-like domain AAA_29 PF13555.1 KEP60919.1 - 0.053 13.0 0.1 8.9 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Pkinase PF00069.20 KEP60920.1 - 3.1e-07 29.8 0.0 2.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Glyco_transf_22 PF03901.12 KEP60921.1 - 2e-80 270.8 7.8 2.7e-80 270.4 5.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HABP4_PAI-RBP1 PF04774.10 KEP60922.1 - 2e-09 37.9 17.0 2e-09 37.9 11.8 3.3 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Tankyrase_bdg_C PF15327.1 KEP60922.1 - 5.2 7.2 12.5 0.72 10.0 0.4 2.5 1 1 1 2 2 2 0 Tankyrase binding protein C terminal domain OTU PF02338.14 KEP60924.1 - 4.5e-06 27.2 0.0 2.1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Kazal_1 PF00050.16 KEP60925.1 - 2e-41 139.7 119.1 2.9e-07 30.3 4.4 10.4 8 2 2 10 10 10 10 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KEP60925.1 - 2.8e-22 78.3 101.3 7.5e-08 32.1 1.8 11.0 11 0 0 11 11 11 10 Kazal-type serine protease inhibitor domain DUF3012 PF11216.3 KEP60925.1 - 3.5 7.3 9.6 17 5.2 0.1 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF3012) Thioredoxin PF00085.15 KEP60926.1 - 5.5e-15 54.9 0.0 8e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEP60926.1 - 0.00031 20.7 0.0 0.0056 16.7 0.0 2.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KEP60926.1 - 0.025 14.6 0.1 0.052 13.5 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Herpes_UL56 PF04534.7 KEP60926.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL56 protein Thioredoxin_2 PF13098.1 KEP60926.1 - 0.13 12.5 0.0 0.54 10.4 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.1 KEP60926.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein AbrB-like PF14250.1 KEP60926.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 AbrB-like transcriptional regulator Ank_5 PF13857.1 KEP60927.1 - 7.4e-05 22.8 0.0 0.0054 16.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEP60927.1 - 0.00042 20.5 0.0 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP60927.1 - 0.02 15.4 0.0 0.064 13.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3452 PF11934.3 KEP60927.1 - 0.034 13.4 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Menin PF05053.8 KEP60927.1 - 0.077 11.1 0.1 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Menin AMP-binding PF00501.23 KEP60928.1 - 1.4e-91 306.9 0.0 1.7e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEP60928.1 - 7.4e-21 74.8 0.2 1.6e-20 73.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3407 PF11887.3 KEP60930.1 - 2.1 7.5 5.2 0.64 9.2 0.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3407) RNA_pol_Rpc4 PF05132.9 KEP60932.1 - 1.1e-14 54.4 0.0 3e-13 49.8 0.0 2.9 1 1 0 1 1 1 1 RNA polymerase III RPC4 DUF3584 PF12128.3 KEP60933.1 - 3 5.0 18.0 4.4 4.5 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 KEP60933.1 - 8.6 5.2 15.7 16 4.2 10.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 KEP60935.1 - 4.5e-50 170.2 0.0 8.6e-49 166.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60935.1 - 2.1e-33 115.4 0.0 2.9e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP60935.1 - 2.1e-10 40.0 0.0 3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEP60935.1 - 0.11 12.1 0.1 1.2 8.8 0.1 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family tRNA-synt_1 PF00133.17 KEP60937.1 - 1.8e-32 112.1 3.4 1.4e-12 46.4 0.1 5.9 5 1 1 6 6 6 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEP60937.1 - 6.6e-23 80.9 0.0 8.2e-09 34.5 0.0 3.9 3 1 1 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KEP60937.1 - 2.6e-10 39.8 0.0 8.5e-10 38.2 0.0 1.8 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Anticodon_1 PF08264.8 KEP60937.1 - 7.1e-10 38.8 0.0 2.2e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 KEP60937.1 - 0.01 14.5 0.0 0.022 13.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1e PF01406.14 KEP60937.1 - 0.1 11.7 0.0 0.56 9.2 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.17 KEP60938.1 - 9.4e-37 124.4 0.0 4.7e-17 61.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP60938.1 - 2.7e-27 94.5 0.1 9.5e-12 44.7 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP60938.1 - 3.6e-20 71.5 0.0 7.6e-07 28.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEP60938.1 - 9e-07 28.5 0.0 0.00017 21.2 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KEP60938.1 - 0.00053 19.7 0.4 0.25 11.1 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 KEP60938.1 - 0.00061 19.6 0.0 0.18 11.6 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif Nuc_sug_transp PF04142.10 KEP60939.1 - 1.5e-07 30.7 3.7 5.5e-07 28.9 2.5 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KEP60939.1 - 2.2e-07 30.9 1.9 2.2e-07 30.9 1.3 2.9 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 KEP60939.1 - 2.2e-06 26.8 12.5 3.4e-06 26.2 8.6 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KEP60939.1 - 3.1e-06 26.8 18.9 3.2e-05 23.6 7.2 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF1440 PF07274.7 KEP60939.1 - 0.0026 17.7 2.4 0.36 10.8 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1440) UPF0546 PF10639.4 KEP60939.1 - 0.017 14.9 1.0 0.047 13.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF1129 PF06570.6 KEP60939.1 - 0.82 8.9 3.9 0.45 9.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) EmrE PF13536.1 KEP60939.1 - 7.9 6.7 27.2 0.03 14.5 2.6 3.4 1 1 1 3 3 3 0 Multidrug resistance efflux transporter Iso_dh PF00180.15 KEP60940.1 - 1.8e-69 234.3 0.0 2.2e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CPW_WPC PF09717.5 KEP60941.1 - 1.5e-61 204.9 38.6 2e-14 53.9 0.1 5.2 5 0 0 5 5 5 5 Plasmodium falciparum domain of unknown function (CPW_WPC) 1-cysPrx_C PF10417.4 KEP60941.1 - 9.1 6.0 6.9 22 4.8 0.0 3.3 4 0 0 4 4 4 0 C-terminal domain of 1-Cys peroxiredoxin Pkinase PF00069.20 KEP60942.1 - 1.4e-13 50.5 0.0 4.2e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60942.1 - 1.9e-10 40.2 0.0 0.00021 20.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase zf-CCCH PF00642.19 KEP60942.1 - 0.0011 18.6 1.5 0.0011 18.6 1.0 4.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) VIT1 PF01988.14 KEP60943.1 - 1.1e-62 211.3 2.1 1.3e-62 211.0 1.5 1.1 1 0 0 1 1 1 1 VIT family DUF2453 PF10507.4 KEP60943.1 - 0.0094 15.7 1.2 0.0094 15.7 0.8 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2453) DUF2532 PF10811.3 KEP60943.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) Sec7 PF01369.15 KEP60945.1 - 8.6e-40 136.4 0.0 1.4e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.13 KEP60945.1 - 2.9e-30 105.3 0.2 5.2e-30 104.5 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_23 PF13489.1 KEP60947.1 - 7e-21 74.6 0.0 1.4e-20 73.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP60947.1 - 2.7e-12 46.5 0.0 2.7e-11 43.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP60947.1 - 7.2e-12 45.8 0.1 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP60947.1 - 1.2e-11 44.8 0.2 2e-10 41.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP60947.1 - 4.6e-11 43.0 0.0 1.3e-10 41.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP60947.1 - 7.7e-07 29.1 0.2 1.7e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP60947.1 - 8.2e-06 26.1 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEP60947.1 - 0.00021 20.7 0.2 0.0016 17.8 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 KEP60947.1 - 0.00027 20.4 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) TPMT PF05724.6 KEP60947.1 - 0.00045 19.7 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 KEP60947.1 - 0.00066 18.8 0.1 0.044 12.8 0.0 2.3 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KEP60947.1 - 0.00081 18.6 0.8 0.0013 17.8 0.5 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KEP60947.1 - 0.02 14.5 0.1 0.049 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 KEP60947.1 - 0.032 13.6 0.2 0.15 11.4 0.0 1.9 1 1 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 KEP60947.1 - 0.041 12.5 0.0 0.13 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) BTB PF00651.26 KEP60948.1 - 3.8e-18 65.4 0.0 8.3e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KEP60948.1 - 0.00042 20.3 0.0 0.00093 19.2 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain MFS_1 PF07690.11 KEP60949.1 - 4.2e-23 81.6 69.9 1.3e-21 76.7 27.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEP60949.1 - 1.3 7.3 39.2 0.049 12.0 6.9 3.6 1 1 2 3 3 3 0 MFS/sugar transport protein Dus PF01207.12 KEP60950.1 - 4.8e-59 199.6 0.0 7.8e-53 179.3 0.0 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF2102 PF09875.4 KEP60950.1 - 0.033 13.7 0.1 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) DUF1235 PF06822.7 KEP60950.1 - 0.07 12.0 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) DUF1768 PF08719.6 KEP60951.1 - 2.9e-08 33.5 0.0 2.9e-08 33.5 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1768) Lge1 PF11488.3 KEP60951.1 - 7.2 6.8 8.7 1.8 8.8 0.0 3.3 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 Cyclin PF08613.6 KEP60952.1 - 1.4e-10 41.7 0.0 2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEP60952.1 - 9.4e-09 34.9 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.20 KEP60953.1 - 2.6e-45 154.6 0.0 3e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60953.1 - 2.6e-21 75.8 0.0 3.3e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP60953.1 - 0.00037 19.5 0.0 0.05 12.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 KEP60953.1 - 0.00076 18.5 0.5 0.0015 17.6 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP60953.1 - 0.013 15.2 0.1 0.029 14.0 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family PDEase_I PF00233.14 KEP60954.1 - 7.4e-55 186.2 0.7 1.1e-54 185.6 0.5 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KEP60954.1 - 0.00071 19.5 0.1 0.0017 18.3 0.1 1.6 1 0 0 1 1 1 1 HD domain HTH_16 PF12645.2 KEP60954.1 - 0.0031 17.4 0.0 0.0098 15.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Tfb4 PF03850.9 KEP60955.1 - 7.4e-32 110.7 2.8 4.8e-31 108.0 1.9 2.0 2 0 0 2 2 2 1 Transcription factor Tfb4 zf-DHHC PF01529.15 KEP60956.1 - 5.6e-30 104.0 7.7 5.6e-30 104.0 5.3 3.2 2 2 0 2 2 2 1 DHHC palmitoyltransferase DUF4583 PF15190.1 KEP60956.1 - 0.36 10.4 2.9 13 5.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4583) Pkinase PF00069.20 KEP60957.1 - 4.1e-40 137.5 0.0 2.8e-34 118.4 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP60957.1 - 8e-17 61.1 0.0 1.4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP60957.1 - 3.9e-05 22.7 0.0 6.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Tubulin PF00091.20 KEP60958.1 - 1.8e-70 237.1 0.0 3e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEP60958.1 - 1e-48 164.5 0.2 1.5e-48 163.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEP60958.1 - 0.00033 20.6 0.0 0.00082 19.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KEP60958.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain ubiquitin PF00240.18 KEP60959.1 - 1.3e-06 27.6 2.5 5.5e-06 25.6 0.3 3.1 4 1 1 5 5 5 1 Ubiquitin family Ubiquitin_2 PF14560.1 KEP60959.1 - 0.031 14.5 2.0 4.3 7.6 0.1 4.3 2 1 3 5 5 5 0 Ubiquitin-like domain Adaptin_N PF01602.15 KEP60960.1 - 1e-73 248.4 1.1 1.9e-73 247.5 0.8 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KEP60960.1 - 5.6e-47 158.6 0.6 3.3e-22 78.5 0.1 2.6 2 0 0 2 2 2 2 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KEP60960.1 - 2.1e-36 124.6 0.0 4.5e-36 123.5 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KEP60960.1 - 1.9e-11 44.1 2.6 6.2e-07 29.6 0.0 4.1 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 KEP60960.1 - 0.0016 18.3 0.1 0.034 14.2 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.2 KEP60960.1 - 0.0079 16.0 7.1 0.0082 16.0 0.2 3.5 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 KEP60960.1 - 0.014 15.2 1.7 0.95 9.4 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Dynamin_N PF00350.18 KEP60960.1 - 0.021 14.6 0.1 0.062 13.1 0.0 1.8 2 0 0 2 2 2 0 Dynamin family HEAT_EZ PF13513.1 KEP60960.1 - 0.062 13.8 2.1 39 4.8 0.0 5.2 4 2 1 5 5 5 0 HEAT-like repeat Arm PF00514.18 KEP60960.1 - 0.25 11.2 5.6 18 5.3 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TPR_16 PF13432.1 KEP60961.1 - 1.2e-06 29.0 1.9 5.1e-06 27.0 1.3 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEP60961.1 - 1.7e-05 24.3 0.1 3.7e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 TPR repeat PDZ PF00595.19 KEP60961.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) TPR_17 PF13431.1 KEP60961.1 - 0.029 14.5 0.0 0.088 13.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEP60961.1 - 0.038 13.7 0.1 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP60961.1 - 0.053 13.4 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP60961.1 - 0.068 12.9 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat PDZ_2 PF13180.1 KEP60961.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 PDZ domain TPR_1 PF00515.23 KEP60961.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP60961.1 - 0.14 12.1 0.8 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.5 KEP60961.1 - 0.17 10.6 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Ribonuclease_3 PF00636.21 KEP60962.1 - 1.1e-13 51.5 0.0 8.3e-13 48.7 0.0 2.4 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KEP60962.1 - 9.3e-05 22.3 0.0 0.00025 21.0 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KEP60963.1 - 1.1e-14 54.8 0.0 1e-07 32.3 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain DEAD PF00270.24 KEP60963.1 - 9.3e-13 48.0 0.0 6.8e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP60963.1 - 4.1e-10 39.3 0.0 1.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP60963.1 - 5.1e-09 36.2 4.1 2.6e-05 24.1 0.0 3.5 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Ribonucleas_3_3 PF14622.1 KEP60963.1 - 3.2e-06 27.1 0.0 0.041 13.8 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease-III-like AAA_19 PF13245.1 KEP60963.1 - 0.0026 17.4 0.7 0.0082 15.8 0.5 1.9 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 KEP60963.1 - 0.98 8.6 0.1 1.7 7.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Ras PF00071.17 KEP60965.1 - 2.4e-33 114.8 0.0 3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP60965.1 - 4.1e-19 69.2 0.0 5.3e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP60965.1 - 7.3e-11 41.6 0.0 9.5e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 KEP60965.1 - 1.7e-05 24.9 0.0 4.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP60965.1 - 0.00078 19.4 2.0 0.0083 16.1 0.1 2.1 1 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KEP60965.1 - 0.00079 19.3 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEP60965.1 - 0.0013 17.9 0.0 0.0047 16.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 KEP60965.1 - 0.0013 18.4 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 KEP60965.1 - 0.0032 17.1 0.8 0.014 15.0 0.0 2.2 2 1 1 3 3 3 1 NACHT domain PduV-EutP PF10662.4 KEP60965.1 - 0.0098 15.3 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KEP60965.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEP60965.1 - 0.013 15.8 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Pox_A32 PF04665.7 KEP60965.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.9 KEP60965.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KEP60965.1 - 0.02 14.3 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KEP60965.1 - 0.022 14.6 0.1 0.099 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 KEP60965.1 - 0.026 13.9 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KEP60965.1 - 0.064 13.1 0.0 0.092 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KEP60965.1 - 0.067 12.6 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KEP60965.1 - 0.072 13.9 0.4 0.17 12.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KEP60965.1 - 0.082 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin NB-ARC PF00931.17 KEP60965.1 - 0.11 11.3 0.0 0.26 10.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 KEP60965.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KEP60965.1 - 0.12 12.6 0.1 0.18 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KEP60965.1 - 0.14 11.4 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Abhydrolase_5 PF12695.2 KEP60966.1 - 2.8e-15 56.3 0.0 5.4e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP60966.1 - 5.9e-15 55.7 0.0 1.4e-14 54.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP60966.1 - 2.9e-07 30.2 0.4 1.1e-05 25.1 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEP60966.1 - 5.8e-05 22.4 0.0 0.00017 20.9 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KEP60966.1 - 0.00038 19.9 0.0 0.00099 18.6 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KEP60966.1 - 0.00081 19.1 0.1 0.005 16.5 0.1 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 KEP60966.1 - 0.0017 17.8 0.1 0.0028 17.1 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 KEP60966.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.11 KEP60966.1 - 0.1 12.0 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF4476 PF14771.1 KEP60966.1 - 0.11 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) DLH PF01738.13 KEP60966.1 - 0.13 11.4 0.0 0.31 10.2 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Ribosomal_L14e PF01929.12 KEP60967.1 - 1.9e-26 92.2 5.0 2.5e-26 91.8 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KEP60967.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 KOW motif OB_RNB PF08206.6 KEP60967.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain MIP PF00230.15 KEP60968.1 - 1.7e-14 53.8 32.2 2.1e-08 33.9 7.5 2.8 1 1 0 2 2 2 2 Major intrinsic protein Pox_P21 PF05313.7 KEP60968.1 - 0.14 11.3 1.8 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein UPF0182 PF03699.8 KEP60968.1 - 0.56 8.0 2.2 0.96 7.2 1.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) AAA PF00004.24 KEP60969.1 - 3.1e-43 147.1 0.0 7e-43 145.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP60969.1 - 5.7e-07 29.7 0.0 0.0012 19.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 KEP60969.1 - 2.1e-06 27.7 0.0 5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEP60969.1 - 1.3e-05 24.9 0.1 7.8e-05 22.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEP60969.1 - 2e-05 23.7 0.0 4.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KEP60969.1 - 4.5e-05 22.4 0.0 7.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 KEP60969.1 - 5.9e-05 23.1 0.0 0.00082 19.4 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KEP60969.1 - 0.00055 20.7 0.7 0.0016 19.2 0.1 2.2 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KEP60969.1 - 0.00076 18.9 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KEP60969.1 - 0.00077 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP60969.1 - 0.0014 18.3 0.2 0.0028 17.3 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEP60969.1 - 0.0014 18.9 0.3 0.0069 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEP60969.1 - 0.0023 17.8 0.1 0.0079 16.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KEP60969.1 - 0.0026 17.6 0.0 0.0063 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEP60969.1 - 0.0034 16.8 0.2 0.061 12.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 KEP60969.1 - 0.0054 15.5 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 KEP60969.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 KEP60969.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEP60969.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KEP60969.1 - 0.013 15.1 0.2 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KEP60969.1 - 0.016 14.8 0.1 0.07 12.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEP60969.1 - 0.017 14.3 0.2 0.097 11.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 KEP60969.1 - 0.018 14.6 0.0 0.23 11.1 0.0 2.2 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.17 KEP60969.1 - 0.021 13.6 0.0 0.072 11.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 KEP60969.1 - 0.037 13.7 0.2 0.42 10.2 0.0 2.4 2 1 0 3 3 3 0 Archaeal ATPase KaiC PF06745.8 KEP60969.1 - 0.066 12.3 0.1 0.51 9.4 0.0 2.2 1 1 1 2 2 2 0 KaiC NTPase_1 PF03266.10 KEP60969.1 - 0.069 12.8 0.5 0.57 9.8 0.1 2.5 2 1 0 2 2 2 0 NTPase AAA_11 PF13086.1 KEP60969.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEP60969.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.12 KEP60969.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GST_C_2 PF13410.1 KEP60970.1 - 0.00013 21.7 1.2 0.0007 19.4 0.0 2.4 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 KEP60970.1 - 0.00025 20.9 0.0 0.24 11.2 0.0 2.7 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_3 PF14497.1 KEP60970.1 - 0.024 15.0 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ERO1 PF04137.10 KEP60971.1 - 6.1e-60 203.1 0.0 7.8e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) FixQ PF05545.6 KEP60971.1 - 0.042 13.4 0.9 0.12 12.0 0.6 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Rifin_STEVOR PF02009.11 KEP60971.1 - 0.15 11.6 1.8 0.21 11.1 1.3 1.2 1 0 0 1 1 1 0 Rifin/stevor family UPF0449 PF15136.1 KEP60972.1 - 0.0046 17.1 3.3 0.0097 16.0 2.3 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 EzrA PF06160.7 KEP60972.1 - 0.01 14.0 5.0 0.012 13.8 3.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3552 PF12072.3 KEP60972.1 - 0.079 12.1 8.2 0.12 11.5 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Atg14 PF10186.4 KEP60972.1 - 0.1 11.5 4.4 0.13 11.1 3.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HlyD_2 PF12700.2 KEP60972.1 - 0.24 10.5 3.3 0.32 10.1 2.3 1.2 1 0 0 1 1 1 0 HlyD family secretion protein LMBR1 PF04791.11 KEP60972.1 - 0.37 9.3 3.3 0.49 8.9 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 KEP60972.1 - 0.53 9.8 4.5 0.69 9.4 3.1 1.2 1 0 0 1 1 1 0 IncA protein DUF4164 PF13747.1 KEP60972.1 - 4 7.6 10.6 7.6 6.7 6.9 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Mito_carr PF00153.22 KEP60973.1 - 3e-10 39.6 0.0 3.2e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.22 KEP60974.1 - 1.7e-68 226.3 1.3 1e-23 82.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4257 PF14074.1 KEP60974.1 - 0.007 15.9 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4257) DUF2828 PF11443.3 KEP60974.1 - 0.16 10.1 0.0 0.22 9.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Aminotran_5 PF00266.14 KEP60975.1 - 1.2e-29 103.2 0.0 1.3e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V CAF1 PF04857.15 KEP60976.1 - 6.2e-35 120.7 0.0 1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease Antigen_Bd37 PF11641.3 KEP60977.1 - 0.09 12.0 0.3 0.19 10.9 0.2 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein RrnaAD PF00398.15 KEP60978.1 - 5.2e-43 146.9 0.0 7.4e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KEP60978.1 - 6.4e-05 22.9 0.0 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP60978.1 - 0.0031 18.0 0.1 0.023 15.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEP60978.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain AAA PF00004.24 KEP60979.1 - 2.5e-41 140.9 0.0 6.9e-41 139.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEP60979.1 - 1.3e-06 28.2 0.1 7.6e-06 25.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEP60979.1 - 8.7e-06 24.9 0.0 9.2e-05 21.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEP60979.1 - 2.4e-05 24.4 0.2 0.0013 18.7 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEP60979.1 - 0.00026 21.1 0.4 0.019 15.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KEP60979.1 - 0.00037 20.4 0.0 0.0014 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KEP60979.1 - 0.0026 17.6 0.2 0.007 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEP60979.1 - 0.004 16.3 0.0 0.011 14.9 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEP60979.1 - 0.0048 16.6 0.3 0.013 15.1 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KEP60979.1 - 0.0049 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 KEP60979.1 - 0.0073 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF815 PF05673.8 KEP60979.1 - 0.0074 15.2 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KEP60979.1 - 0.0092 16.8 0.1 0.045 14.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEP60979.1 - 0.018 14.4 0.4 0.13 11.6 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KEP60979.1 - 0.031 13.8 0.1 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEP60979.1 - 0.032 13.3 0.1 0.071 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 KEP60979.1 - 0.046 12.4 0.0 0.12 11.0 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus AAA_14 PF13173.1 KEP60979.1 - 0.047 13.5 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KEP60979.1 - 0.071 12.2 0.9 0.22 10.5 0.0 2.2 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.21 KEP60979.1 - 0.082 12.3 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4061 PF13270.1 KEP60979.1 - 0.12 12.4 1.0 3.1 7.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) NACHT PF05729.7 KEP60979.1 - 0.13 11.8 0.3 2.5 7.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain SNARE PF05739.14 KEP60980.1 - 7.8e-08 31.8 2.3 1.5e-07 30.9 1.6 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin-6_N PF09177.6 KEP60980.1 - 0.028 14.7 1.3 0.071 13.5 0.2 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FliT PF05400.8 KEP60980.1 - 0.091 13.1 5.4 2.4 8.6 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein FliT BRE1 PF08647.6 KEP60980.1 - 0.13 12.2 0.9 8.5 6.4 0.0 2.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase LSM PF01423.17 KEP60981.1 - 7.8e-17 60.5 0.2 1.7e-16 59.5 0.1 1.5 1 1 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 KEP60981.1 - 0.062 12.8 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin tRNA-synt_2b PF00587.20 KEP60984.1 - 8.5e-40 136.1 0.0 1.5e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEP60984.1 - 7.2e-20 70.7 0.1 2e-19 69.3 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 KEP60984.1 - 2.9e-10 39.8 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 KEP60984.1 - 0.00058 19.6 0.0 0.0021 17.8 0.0 2.0 1 1 0 1 1 1 1 TGS domain DUF2188 PF09954.4 KEP60984.1 - 0.021 14.7 0.8 0.063 13.2 0.5 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) MtN3_slv PF03083.11 KEP60985.1 - 1.7e-40 136.7 7.0 2.7e-20 72.0 0.2 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.9 KEP60985.1 - 1.6 8.3 7.6 1.2 8.7 0.1 3.5 3 0 0 3 3 3 0 PQ loop repeat Syntaxin-6_N PF09177.6 KEP60986.1 - 1e-13 51.5 0.2 1e-13 51.5 0.1 2.6 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 KEP60986.1 - 5e-07 29.3 9.8 5e-07 29.3 6.8 2.7 4 0 0 4 4 4 1 SNARE domain DUF3227 PF11537.3 KEP60986.1 - 0.012 15.7 0.5 0.43 10.7 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3227) DUF2721 PF11026.3 KEP60986.1 - 0.033 13.8 2.4 0.091 12.3 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF948 PF06103.6 KEP60986.1 - 0.039 13.7 3.8 0.39 10.6 2.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.8 KEP60986.1 - 3.5 7.4 11.7 2.4 7.9 0.8 3.9 4 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 SNase PF00565.12 KEP60987.1 - 1.9e-16 60.2 1.4 1.7e-07 31.4 0.1 2.7 2 1 0 2 2 2 2 Staphylococcal nuclease homologue Histone PF00125.19 KEP60989.1 - 1.9e-21 75.9 0.1 2.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEP60989.1 - 0.00012 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L37ae PF01780.14 KEP60990.1 - 1.5e-39 133.6 9.8 1.8e-39 133.4 6.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KEP60990.1 - 0.0053 16.5 2.9 0.0075 16.0 2.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KEP60990.1 - 0.0055 16.1 2.4 0.066 12.6 0.0 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KEP60990.1 - 0.04 13.5 0.7 0.059 13.0 0.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Di19 PF05605.7 KEP60990.1 - 0.063 13.4 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KEP60990.1 - 0.064 13.6 1.2 3.8 8.0 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Elf1 PF05129.8 KEP60990.1 - 0.15 11.7 2.0 0.27 10.9 1.4 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 KEP60990.1 - 0.16 12.3 1.1 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 KEP60990.1 - 0.4 10.4 3.2 2.9 7.7 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 KEP60990.1 - 0.75 10.2 5.6 2.5 8.6 0.2 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Lar_restr_allev PF14354.1 KEP60990.1 - 1.1 9.5 3.8 2.9 8.2 2.6 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_L44 PF00935.14 KEP60990.1 - 6.7 6.7 8.5 15 5.6 4.9 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 DUF2205 PF10224.4 KEP60991.1 - 0.00058 19.3 1.8 0.00058 19.3 1.3 3.4 3 0 0 3 3 3 1 Predicted coiled-coil protein (DUF2205) CRIC_ras_sig PF10534.4 KEP60991.1 - 0.013 15.4 0.2 0.013 15.4 0.1 1.9 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras Daxx PF03344.10 KEP60991.1 - 0.1 11.0 37.3 0.13 10.7 25.8 1.0 1 0 0 1 1 1 0 Daxx Family SR-25 PF10500.4 KEP60991.1 - 0.2 11.1 57.8 0.1 12.0 15.2 3.2 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein Nup54 PF13874.1 KEP60991.1 - 0.57 9.8 13.0 0.045 13.4 1.7 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 UBA_4 PF14555.1 KEP60993.1 - 7.8e-11 41.3 0.4 1.4e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 KEP60993.1 - 5.8e-08 32.6 2.1 7.5e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like EF1G PF00647.14 KEP60994.1 - 2e-39 133.5 0.1 5.1e-39 132.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KEP60994.1 - 2.4e-11 43.4 0.0 6.2e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEP60994.1 - 9.4e-10 38.5 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEP60994.1 - 5.1e-09 36.5 0.0 1.3e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEP60994.1 - 6.7e-09 35.8 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEP60994.1 - 1.6e-07 31.1 0.0 8.1e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEP60994.1 - 2.7e-06 27.2 0.0 6.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AMA-1 PF02430.10 KEP60995.1 - 5.4e-56 190.4 3.0 8.4e-56 189.7 2.1 1.3 1 0 0 1 1 1 1 Apical membrane antigen 1 Aminotran_5 PF00266.14 KEP60996.1 - 3.1e-59 200.5 0.0 4.7e-57 193.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V RLL PF10036.4 KEP60997.1 - 9.8e-29 100.5 0.0 1.2e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein CLAG PF03805.8 KEP60998.1 - 2.7e-08 31.7 0.8 0.00087 16.7 0.0 3.1 3 0 0 3 3 3 3 Cytoadherence-linked asexual protein DUF454 PF04304.8 KEP60998.1 - 0.0063 16.5 1.8 0.049 13.6 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF454) ACDC PF14733.1 KEP60999.1 - 2e-09 37.4 3.5 0.0006 19.8 0.3 2.7 3 0 0 3 3 3 2 AP2-coincident C-terminal SPC22 PF04573.7 KEP61000.1 - 5.8e-41 139.6 0.0 6.7e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Flavi_NS2A PF01005.14 KEP61001.1 - 0.028 13.7 0.1 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A CSF-1 PF05337.6 KEP61001.1 - 0.069 12.4 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) UQ_con PF00179.21 KEP61004.1 - 1.3e-38 131.6 0.0 1.8e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAST_1 PF06743.10 KEP61005.1 - 0.022 14.4 0.0 3.5 7.4 0.0 3.6 3 1 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Peptidase_M41 PF01434.13 KEP61006.1 - 1.2e-61 207.8 0.2 2.5e-61 206.8 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEP61006.1 - 5.6e-41 139.8 0.0 1.4e-40 138.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEP61006.1 - 5.5e-05 22.3 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KEP61006.1 - 0.00011 23.0 0.1 0.00041 21.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KEP61006.1 - 0.00018 21.2 2.2 0.00023 20.8 0.1 2.4 2 0 0 2 2 1 1 Part of AAA domain TIP49 PF06068.8 KEP61006.1 - 0.00019 20.2 0.1 0.0004 19.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 KEP61006.1 - 0.00036 20.6 2.0 0.016 15.3 0.1 3.4 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEP61006.1 - 0.00039 20.1 0.1 0.0024 17.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEP61006.1 - 0.0033 16.8 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 KEP61006.1 - 0.005 16.8 0.1 0.005 16.8 0.1 4.3 3 2 1 4 4 4 1 AAA ATPase domain AAA_28 PF13521.1 KEP61006.1 - 0.0066 16.4 0.9 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEP61006.1 - 0.0079 15.8 0.4 0.22 11.1 0.0 2.9 1 1 0 2 2 2 1 NACHT domain AAA_11 PF13086.1 KEP61006.1 - 0.013 15.0 2.2 0.86 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KEP61006.1 - 0.022 13.8 0.1 0.059 12.5 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KEP61006.1 - 0.03 13.4 0.0 0.03 13.4 0.0 2.8 2 1 1 3 3 3 0 Zeta toxin AAA_33 PF13671.1 KEP61006.1 - 0.042 13.7 4.0 0.092 12.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEP61006.1 - 0.055 13.7 1.8 0.059 13.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 KEP61006.1 - 0.068 12.5 2.1 0.26 10.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEP61006.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L18e PF00828.14 KEP61008.1 - 5e-23 81.8 0.2 8.1e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Archease PF01951.11 KEP61009.1 - 3e-48 163.2 0.1 3.8e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Mu-like_Com PF10122.4 KEP61010.1 - 0.0047 15.9 20.4 0.7 8.9 2.8 3.9 2 2 2 4 4 4 3 Mu-like prophage protein Com Ribosomal_S27e PF01667.12 KEP61010.1 - 0.015 14.8 0.6 0.015 14.8 0.4 2.6 2 1 0 2 2 2 0 Ribosomal protein S27 HypA PF01155.14 KEP61010.1 - 0.048 13.3 4.6 0.4 10.3 0.5 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 KEP61010.1 - 1.8 8.9 6.3 6e+02 0.8 4.4 3.4 1 1 0 1 1 1 0 Restriction alleviation protein Lar Prok-RING_1 PF14446.1 KEP61010.1 - 1.9 8.2 6.5 3.3 7.4 0.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TPR_11 PF13414.1 KEP61011.1 - 6e-27 93.0 0.0 9.1e-11 41.2 0.0 3.9 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 KEP61011.1 - 1.5e-19 68.7 1.6 3e-05 23.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP61011.1 - 1.5e-19 68.2 6.0 8.2e-05 22.2 0.2 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEP61011.1 - 3.3e-13 49.3 14.1 6.1e-06 26.0 0.8 4.9 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEP61011.1 - 3.9e-13 48.1 0.0 0.0013 18.3 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEP61011.1 - 1.5e-12 47.8 11.3 0.00068 20.2 0.3 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEP61011.1 - 1.7e-09 37.1 0.1 0.0033 17.4 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEP61011.1 - 3e-09 36.6 13.4 0.0064 17.0 0.1 5.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEP61011.1 - 6e-09 35.7 8.3 0.12 12.8 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEP61011.1 - 1.7e-07 31.4 6.4 0.0017 18.6 0.2 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP61011.1 - 6.2e-07 29.1 8.8 7.7e-07 28.8 0.2 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP61011.1 - 0.00032 20.2 4.5 0.044 13.5 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 KEP61011.1 - 0.0021 16.9 0.0 0.055 12.2 0.0 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 KEP61011.1 - 0.0023 17.0 4.5 0.0035 16.4 1.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 KEP61011.1 - 0.0039 16.4 0.0 0.0054 15.9 0.0 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain RPN7 PF10602.4 KEP61011.1 - 0.006 15.9 0.1 0.09 12.1 0.0 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN7 SNAP PF14938.1 KEP61011.1 - 0.028 13.5 1.3 0.59 9.2 0.1 2.6 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 KEP61011.1 - 0.39 10.7 11.4 3.5 7.6 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4355 PF14265.1 KEP61013.1 - 0.073 13.0 2.0 0.13 12.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) tRNA-synt_1e PF01406.14 KEP61014.1 - 5.1e-120 400.1 0.0 8.2e-120 399.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KEP61014.1 - 1.1e-09 37.4 0.1 0.00096 17.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEP61014.1 - 0.0012 16.9 0.0 0.0036 15.3 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DUF1266 PF06889.6 KEP61014.1 - 0.037 13.8 1.3 0.092 12.5 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Peptidase_C70 PF12385.3 KEP61014.1 - 0.099 12.3 0.1 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 ATPase_gene1 PF09527.5 KEP61017.1 - 2.4 8.0 9.6 12 5.7 0.3 2.7 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) SIMPL PF04402.9 KEP61019.1 - 0.0035 17.2 0.3 0.0045 16.8 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF541) DAGAT PF03982.8 KEP61020.1 - 1.5e-20 73.1 0.0 1.7e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.8 KEP61021.1 - 8.1e-36 123.2 0.1 1.1e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 KEP61021.1 - 0.042 13.2 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase Pkinase PF00069.20 KEP61023.1 - 2e-45 155.0 0.0 2.7e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61023.1 - 4.8e-19 68.4 0.0 7.5e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEP61023.1 - 0.0018 17.4 0.2 0.0041 16.2 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP61023.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family HECT PF00632.20 KEP61024.1 - 3.4e-98 328.6 0.0 4.9e-98 328.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KEP61024.1 - 0.25 11.0 3.0 0.22 11.2 0.3 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF4456 PF14644.1 KEP61026.1 - 0.008 15.4 6.5 26 3.9 0.0 6.4 6 1 1 7 7 7 3 Domain of unknown function (DUF4456) PPR_2 PF13041.1 KEP61026.1 - 0.23 11.4 0.0 38 4.3 0.0 3.5 3 0 0 3 3 3 0 PPR repeat family LCM PF04072.9 KEP61027.1 - 1.9e-25 89.4 0.1 3.8e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase IMCp PF12314.3 KEP61028.1 - 5e-25 87.4 30.8 5e-25 87.4 21.4 4.9 1 1 2 4 4 4 2 Inner membrane complex protein AAA_2 PF07724.9 KEP61030.1 - 4.4e-57 192.7 0.0 5.4e-53 179.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEP61030.1 - 6.4e-26 91.1 0.0 8e-14 51.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEP61030.1 - 1.3e-25 89.1 0.2 6.6e-25 86.8 0.2 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 KEP61030.1 - 4.1e-21 74.6 0.1 1.2e-11 44.3 0.0 2.8 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 KEP61030.1 - 7.6e-19 67.8 0.3 1e-12 47.9 0.0 4.1 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEP61030.1 - 2.5e-12 47.1 0.1 0.00017 21.6 0.0 4.5 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KEP61030.1 - 3e-09 37.1 0.9 0.011 15.8 0.0 4.7 3 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 KEP61030.1 - 1.6e-07 30.9 0.0 2.1e-05 24.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KEP61030.1 - 1.6e-07 31.6 0.0 0.0096 16.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KEP61030.1 - 3.7e-07 30.0 0.0 0.049 13.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 KEP61030.1 - 2.8e-06 26.8 0.0 0.11 11.9 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 KEP61030.1 - 3.6e-06 27.7 3.7 0.026 15.3 0.0 4.1 2 2 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KEP61030.1 - 1.2e-05 25.1 1.1 0.49 10.0 0.0 4.6 2 2 1 3 3 3 2 Archaeal ATPase Mg_chelatase PF01078.16 KEP61030.1 - 0.00011 21.4 0.1 0.4 9.8 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KEP61030.1 - 0.00028 20.0 0.0 0.016 14.2 0.0 3.1 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 KEP61030.1 - 0.00037 20.2 0.0 0.29 10.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.6 KEP61030.1 - 0.00037 20.3 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Torsin AAA_24 PF13479.1 KEP61030.1 - 0.00043 19.9 0.0 0.19 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEP61030.1 - 0.00064 19.7 0.0 0.84 9.5 0.0 3.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEP61030.1 - 0.00099 19.2 0.0 0.98 9.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KEP61030.1 - 0.0018 17.7 0.0 0.46 9.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.6 KEP61030.1 - 0.0039 16.8 0.0 1.4 8.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KEP61030.1 - 0.0059 16.5 0.0 0.32 10.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEP61030.1 - 0.0062 15.7 0.0 3.7 6.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KEP61030.1 - 0.009 16.3 0.1 1.1 9.5 0.0 3.1 3 0 0 3 3 2 1 ABC transporter Miro PF08477.8 KEP61030.1 - 0.0094 16.4 0.0 1.5 9.3 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KEP61030.1 - 0.017 14.5 2.0 0.43 9.9 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain UPF0079 PF02367.12 KEP61030.1 - 0.019 14.5 0.0 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KEP61030.1 - 0.019 14.6 0.1 0.74 9.5 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KEP61030.1 - 0.021 14.5 1.0 17 5.0 0.0 3.8 4 0 0 4 4 3 0 NTPase AAA_19 PF13245.1 KEP61030.1 - 0.023 14.4 0.0 0.51 10.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain ATP_bind_1 PF03029.12 KEP61030.1 - 0.028 13.9 0.0 0.46 9.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein LSM PF01423.17 KEP61034.1 - 1.7e-16 59.4 0.1 2.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain Di19_C PF14571.1 KEP61035.1 - 1.2 9.4 6.4 0.55 10.5 0.2 2.5 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal Bap31 PF05529.7 KEP61036.1 - 0.0013 18.1 6.3 0.012 15.1 4.3 2.7 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF1510 PF07423.6 KEP61036.1 - 0.0026 17.1 3.3 0.0033 16.8 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) GLTT PF01744.15 KEP61036.1 - 0.048 13.0 0.2 0.14 11.6 0.2 1.8 2 0 0 2 2 2 0 GLTT repeat (6 copies) DUF4512 PF14975.1 KEP61036.1 - 0.23 12.3 3.6 1.3 9.9 2.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) APG6 PF04111.7 KEP61036.1 - 6.7 5.6 8.9 8.5 5.3 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 F-box-like PF12937.2 KEP61037.1 - 4.6e-05 23.0 0.5 4.6e-05 23.0 0.3 1.9 2 0 0 2 2 2 1 F-box-like DUF2217 PF10265.4 KEP61037.1 - 4.1 6.0 10.2 7 5.2 2.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) cEGF PF12662.2 KEP61038.1 - 4.6e-09 35.7 19.9 0.00018 21.0 0.1 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.22 KEP61038.1 - 3.3e-07 30.1 43.3 0.00027 20.8 3.1 5.8 4 1 1 5 5 5 4 EGF-like domain FXa_inhibition PF14670.1 KEP61038.1 - 0.51 10.5 45.0 0.24 11.5 3.2 5.8 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site CcmD PF04995.9 KEP61038.1 - 6.2 6.6 5.1 2.6 7.8 1.2 2.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) EGF_3 PF12947.2 KEP61038.1 - 9.1 6.3 61.1 0.7 9.9 3.1 6.5 6 1 1 7 7 7 0 EGF domain cEGF PF12662.2 KEP61039.1 - 2.6e-07 30.1 32.0 0.00015 21.2 3.2 5.1 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.22 KEP61039.1 - 0.00014 21.7 6.4 0.00014 21.7 4.5 5.9 5 1 0 5 5 5 2 EGF-like domain FXa_inhibition PF14670.1 KEP61039.1 - 0.0094 16.0 6.0 0.0094 16.0 4.2 5.7 4 1 1 5 5 5 2 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KEP61039.1 - 0.48 10.4 55.5 0.033 14.1 7.8 5.6 5 0 0 5 5 5 0 EGF domain hEGF PF12661.2 KEP61039.1 - 1.2 9.3 19.2 0.28 11.3 0.6 5.1 4 0 0 4 4 4 0 Human growth factor-like EGF SRP72 PF08492.7 KEP61040.1 - 8.4e-12 45.2 8.6 8.4e-12 45.2 5.9 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 KEP61040.1 - 1.4e-11 44.5 33.1 0.0014 18.9 0.8 7.8 6 2 1 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 KEP61040.1 - 9.7e-09 35.2 8.5 1.3e-05 25.2 0.4 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEP61040.1 - 6.6e-08 32.3 34.4 0.0085 16.0 1.0 7.7 6 2 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP61040.1 - 7.8e-07 28.5 25.2 0.062 13.2 0.7 9.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP61040.1 - 2.1e-05 25.0 41.4 0.00051 20.6 0.5 8.3 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEP61040.1 - 4.8e-05 23.6 46.6 0.14 12.8 0.1 10.5 7 4 3 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEP61040.1 - 0.00047 19.7 14.9 0.077 12.6 0.5 6.1 6 2 2 8 8 8 3 TPR repeat TPR_4 PF07721.9 KEP61040.1 - 0.0006 20.0 52.7 0.39 11.2 0.0 10.5 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEP61040.1 - 0.0069 16.2 21.8 0.25 11.2 0.2 6.3 5 2 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 KEP61040.1 - 0.015 14.1 11.5 0.023 13.4 0.0 4.4 5 1 0 6 6 6 0 NMDA receptor-regulated protein 1 LppC PF04348.8 KEP61040.1 - 0.042 12.4 4.5 0.017 13.6 1.0 1.8 2 0 0 2 2 2 0 LppC putative lipoprotein YfdX PF10938.3 KEP61040.1 - 0.73 9.4 6.5 2.1 8.0 0.6 3.8 4 0 0 4 4 4 0 YfdX protein TPR_10 PF13374.1 KEP61040.1 - 1.5 8.8 27.4 6.2 6.8 0.1 9.0 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP61040.1 - 2.9 7.6 14.9 3.8 7.2 0.6 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat S10_plectin PF03501.10 KEP61041.1 - 4.9e-40 135.3 0.2 5.7e-40 135.0 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.4 KEP61041.1 - 0.042 13.7 0.1 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DNA_pol_A_exo1 PF01612.15 KEP61042.1 - 1.3e-12 47.5 0.0 5.3e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease DUF4499 PF14934.1 KEP61042.1 - 0.052 13.4 0.0 0.85 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4499) DUF3516 PF12029.3 KEP61042.1 - 0.053 12.3 0.2 0.09 11.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) PP2C PF00481.16 KEP61043.1 - 9e-12 44.9 0.0 4e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF3220 PF11516.3 KEP61043.1 - 0.11 12.4 0.3 10 6.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3120) Tubulin PF00091.20 KEP61046.1 - 1.3e-59 201.6 0.0 1.7e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEP61046.1 - 2.6e-09 37.1 0.0 4.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Spc97_Spc98 PF04130.8 KEP61046.1 - 0.02 13.2 0.4 0.03 12.6 0.3 1.2 1 0 0 1 1 1 0 Spc97 / Spc98 family Coq4 PF05019.8 KEP61047.1 - 6.6e-59 198.5 0.2 1.9e-51 174.1 0.1 2.3 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DEADboxA PF12343.3 KEP61049.1 - 0.065 13.4 2.8 0.068 13.4 2.0 1.1 1 0 0 1 1 1 0 Cold shock protein DEAD box A TMEM51 PF15345.1 KEP61049.1 - 0.28 10.8 1.9 0.29 10.8 1.3 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Cyt-b5 PF00173.23 KEP61051.1 - 8.1e-25 86.4 0.0 1e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.1 KEP61051.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 YqzH-like protein SET PF00856.23 KEP61052.1 - 4.4e-09 36.8 0.2 6.1e-06 26.6 0.1 2.7 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 KEP61052.1 - 5.8e-09 35.6 11.3 5.8e-09 35.6 7.8 3.0 4 0 0 4 4 4 1 MYND finger Peptidase_C1 PF00112.18 KEP61053.1 - 2e-32 112.8 3.9 3.3e-32 112.1 2.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.6 KEP61053.1 - 2.3e-09 37.4 0.1 1.9e-07 31.2 0.0 2.6 2 0 0 2 2 2 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 KEP61053.1 - 0.031 12.8 3.2 0.047 12.2 2.2 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Sigma70_ner PF04546.8 KEP61053.1 - 2.4 7.7 4.7 3.7 7.0 3.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Arf PF00025.16 KEP61054.1 - 2.8e-78 261.1 0.1 3.2e-78 260.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEP61054.1 - 2.7e-14 52.8 0.0 3.3e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KEP61054.1 - 3.4e-13 49.2 0.0 3.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEP61054.1 - 3.8e-12 45.8 0.0 4.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KEP61054.1 - 2.5e-11 42.8 0.8 5.3e-08 31.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KEP61054.1 - 1.2e-08 35.4 0.0 1.7e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEP61054.1 - 2.4e-05 24.2 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KEP61054.1 - 0.006 15.6 0.2 0.011 14.8 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KEP61054.1 - 0.0099 15.3 0.1 0.08 12.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KEP61054.1 - 0.052 13.4 0.1 0.09 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AMP-binding PF00501.23 KEP61055.1 - 5.3e-34 117.3 0.0 1.1e-33 116.3 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme PI3_PI4_kinase PF00454.22 KEP61056.1 - 1.6e-24 86.6 0.0 3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3591 PF12157.3 KEP61057.1 - 5.9e-21 74.3 0.0 8.4e-07 27.7 0.0 4.9 4 1 0 4 4 4 4 Protein of unknown function (DUF3591) Bromodomain PF00439.20 KEP61057.1 - 7.5e-17 61.0 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.1 KEP61057.1 - 0.00015 21.3 1.3 0.00044 19.8 0.9 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KEP61057.1 - 0.0086 15.9 0.2 0.022 14.6 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle RXT2_N PF08595.6 KEP61057.1 - 0.026 14.3 1.7 3.9 7.2 0.0 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Drf_GBD PF06371.8 KEP61057.1 - 0.42 9.9 0.5 0.97 8.7 0.4 1.5 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain UPF0047 PF01894.12 KEP61057.1 - 0.61 9.9 0.0 1.4 8.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 CDP-OH_P_transf PF01066.16 KEP61058.1 - 1.2e-13 51.1 3.9 1.2e-13 51.1 2.7 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3514 PF12027.3 KEP61058.1 - 0.068 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3514) His_Phos_1 PF00300.17 KEP61061.1 - 7.1e-14 52.2 0.1 1.7e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ribosomal_L12 PF00542.14 KEP61063.1 - 2.1e-24 85.2 9.9 2.8e-22 78.4 4.9 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain LRR_4 PF12799.2 KEP61064.1 - 9.6e-17 60.2 17.9 4.6e-06 26.1 0.3 5.8 3 3 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEP61064.1 - 4.8e-08 31.9 15.1 1 9.6 0.1 8.2 4 3 3 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 KEP61064.1 - 3.3e-07 29.9 16.8 0.0034 17.0 2.0 5.0 1 1 5 6 6 6 5 Leucine rich repeat LRR_7 PF13504.1 KEP61064.1 - 3.4e-07 29.3 9.1 14 6.4 0.1 8.5 8 2 0 8 8 8 1 Leucine rich repeat LRR_6 PF13516.1 KEP61064.1 - 0.0012 18.7 9.3 24 5.3 0.0 7.1 4 2 2 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.1 KEP61064.1 - 0.0041 16.7 4.4 0.11 11.9 0.3 3.0 1 1 3 4 4 4 1 Leucine-rich repeat TT_ORF2 PF02957.10 KEP61064.1 - 0.1 13.2 3.9 0.18 12.4 2.7 1.4 1 0 0 1 1 1 0 TT viral ORF2 adh_short_C2 PF13561.1 KEP61065.1 - 5.5e-96 320.9 0.0 6.8e-96 320.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Enoyl_reductase PF12241.3 KEP61065.1 - 0.00084 18.3 0.2 0.088 11.7 0.0 2.2 1 1 1 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region Es2 PF09751.4 KEP61066.1 - 1.5e-31 110.3 12.6 2.8e-20 73.1 1.6 2.7 2 1 1 3 3 3 2 Nuclear protein Es2 DUF4516 PF14990.1 KEP61068.1 - 0.18 11.3 2.2 0.32 10.5 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4516) tRNA-synt_1b PF00579.20 KEP61071.1 - 3.6e-58 197.0 0.0 4.5e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Histone PF00125.19 KEP61072.1 - 4.5e-19 68.3 0.1 6.1e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 KEP61072.1 - 0.00018 21.6 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KEP61072.1 - 0.00046 20.1 0.2 0.0011 19.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Metallophos PF00149.23 KEP61074.1 - 8.6e-28 97.1 0.1 1.9e-27 96.0 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.1 KEP61074.1 - 5.3e-20 71.3 6.9 2e-08 34.2 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KEP61074.1 - 2e-17 61.0 7.4 0.00042 19.4 0.0 7.1 9 0 0 9 9 9 5 EF hand EF-hand_8 PF13833.1 KEP61074.1 - 2.5e-15 55.8 8.0 3.5e-09 36.1 0.1 5.6 6 0 0 6 6 6 2 EF-hand domain pair CAP_GLY PF01302.20 KEP61074.1 - 1e-14 53.9 0.3 2.1e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_6 PF13405.1 KEP61074.1 - 4.1e-10 38.6 12.9 0.03 14.1 0.0 7.3 5 1 1 6 6 6 3 EF-hand domain EF-hand_5 PF13202.1 KEP61074.1 - 3.9e-08 32.2 3.7 0.00086 18.5 0.0 4.8 5 0 0 5 5 5 2 EF hand PPP5 PF08321.7 KEP61074.1 - 6.3e-05 22.9 0.0 0.00027 20.8 0.0 2.1 1 0 0 1 1 1 1 PPP5 TPR repeat region IQ PF00612.22 KEP61074.1 - 0.00024 20.4 1.4 0.00076 18.9 1.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1880 PF08976.6 KEP61074.1 - 0.001 19.2 0.0 0.055 13.5 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1880) EF-hand_4 PF12763.2 KEP61074.1 - 0.13 11.9 0.2 9.9 5.9 0.0 3.6 4 1 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand Macoilin PF09726.4 KEP61075.1 - 2.3 6.4 12.8 3.6 5.7 8.8 1.3 1 0 0 1 1 1 0 Transmembrane protein eIF-5a PF01287.15 KEP61077.1 - 1.4e-25 89.0 0.2 2e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 KEP61077.1 - 0.0011 18.7 0.1 0.0022 17.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 KEP61077.1 - 0.05 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 KOW motif zf-RanBP PF00641.13 KEP61079.1 - 0.0063 15.5 6.0 0.012 14.7 4.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MIP-T3 PF10243.4 KEP61079.1 - 1.8 6.9 23.6 2.4 6.4 16.4 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HSP70 PF00012.15 KEP61080.1 - 4.2e-268 890.2 13.2 4.9e-268 890.0 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEP61080.1 - 5e-15 54.9 5.4 8e-14 50.9 1.4 2.6 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 KEP61080.1 - 0.00019 21.2 1.8 0.72 9.7 0.0 3.8 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KEP61080.1 - 0.00044 19.9 0.2 0.0051 16.4 0.0 2.5 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain HBS1_N PF08938.5 KEP61080.1 - 0.026 14.6 2.3 0.09 12.9 1.6 2.0 1 0 0 1 1 1 0 HBS1 N-terminus YqfQ PF14181.1 KEP61081.1 - 1.9 8.5 16.9 6.4 6.7 11.7 1.9 1 0 0 1 1 1 0 YqfQ-like protein Ycf1 PF05758.7 KEP61081.1 - 2 6.0 11.1 3.4 5.2 7.7 1.2 1 0 0 1 1 1 0 Ycf1 Presenilin PF01080.12 KEP61081.1 - 2.9 6.6 3.8 6 5.5 2.6 1.5 1 0 0 1 1 1 0 Presenilin DUF1510 PF07423.6 KEP61081.1 - 3.2 7.0 24.1 0.013 14.9 9.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Zip PF02535.17 KEP61081.1 - 7.6 5.4 5.7 19 4.1 4.0 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter PA28_beta PF02252.13 KEP61082.1 - 7.3e-59 197.5 0.3 1.2e-58 196.9 0.2 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 KEP61082.1 - 0.024 14.7 0.5 0.068 13.3 0.1 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit DrrA_P4M PF14860.1 KEP61082.1 - 0.097 12.4 0.3 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain MORN PF02493.15 KEP61083.1 - 8.9e-27 91.2 42.3 1.6e-07 30.6 0.9 7.2 7 0 0 7 7 7 6 MORN repeat SM-ATX PF14438.1 KEP61083.1 - 0.094 12.6 1.1 18 5.3 0.0 3.0 2 1 1 3 3 3 0 Ataxin 2 SM domain AP2 PF00847.15 KEP61085.1 - 1.7e-08 34.4 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 AP2 domain Zip PF02535.17 KEP61087.1 - 0.51 9.2 5.3 7 5.5 3.7 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter DDHD PF02862.12 KEP61087.1 - 0.56 9.9 15.6 2.2 7.9 5.8 2.8 2 0 0 2 2 2 0 DDHD domain RNase_H2-Ydr279 PF09468.5 KEP61087.1 - 3.6 6.6 5.5 11 5.0 3.8 1.8 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) V-SNARE_C PF12352.3 KEP61088.1 - 0.0017 18.3 1.1 0.0055 16.7 0.1 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEP61088.1 - 0.024 14.3 0.4 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 Sec20 Dysbindin PF04440.11 KEP61088.1 - 0.039 13.6 1.3 0.16 11.7 0.9 2.2 1 1 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) tRNA-synt_2b PF00587.20 KEP61089.1 - 4.7e-34 117.4 0.0 7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KEP61089.1 - 5.5e-22 77.8 4.5 1.2e-21 76.7 3.1 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.1 KEP61089.1 - 0.0084 15.9 0.7 0.14 11.9 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4337) TCTP PF00838.12 KEP61090.1 - 3.5e-47 160.4 0.2 4e-47 160.2 0.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein MgsA_C PF12002.3 KEP61091.1 - 7.7e-51 172.1 0.1 1.6e-50 171.1 0.1 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 KEP61091.1 - 2.5e-15 56.1 0.1 3.7e-09 35.9 0.0 2.7 1 1 1 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KEP61091.1 - 3.9e-13 49.7 0.0 8.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KEP61091.1 - 2.2e-07 29.9 0.5 0.00076 18.2 0.0 2.5 2 1 0 3 3 3 2 TIP49 C-terminus AAA_5 PF07728.9 KEP61091.1 - 1.4e-06 28.0 0.0 3.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEP61091.1 - 3.1e-05 23.8 0.0 7.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEP61091.1 - 3.3e-05 23.1 0.7 0.058 12.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEP61091.1 - 0.00025 20.5 0.1 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 KEP61091.1 - 0.0014 18.6 3.7 0.33 10.9 0.1 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_3 PF07726.6 KEP61091.1 - 0.0031 17.1 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP61091.1 - 0.0038 17.3 1.5 0.25 11.5 1.0 3.0 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KEP61091.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Viral_helicase1 PF01443.13 KEP61091.1 - 0.045 13.2 0.2 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KEP61091.1 - 0.088 12.4 0.0 8 6.0 0.0 2.5 1 1 0 2 2 2 0 Archaeal ATPase DNA_pol3_delta2 PF13177.1 KEP61091.1 - 0.092 12.3 0.0 0.31 10.6 0.0 1.6 1 1 1 2 2 2 0 DNA polymerase III, delta subunit Rad17 PF03215.10 KEP61091.1 - 0.11 11.1 0.6 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF2951 PF11166.3 KEP61092.1 - 0.064 13.1 1.7 0.14 12.0 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Neur_chan_memb PF02932.11 KEP61092.1 - 0.073 12.9 1.9 0.088 12.6 1.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.8 KEP61092.1 - 0.089 11.4 2.8 0.11 11.2 1.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3527 PF12043.3 KEP61092.1 - 0.2 11.1 4.1 0.24 10.8 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) LIN37 PF15306.1 KEP61092.1 - 0.21 11.6 5.6 0.31 11.0 3.9 1.3 1 0 0 1 1 1 0 LIN37 Plasmodium_Vir PF05795.6 KEP61092.1 - 0.26 10.4 2.4 0.32 10.1 1.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MAP7 PF05672.6 KEP61092.1 - 0.44 9.9 26.0 0.34 10.2 17.1 1.4 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family Hid1 PF12722.2 KEP61092.1 - 1.7 6.2 3.6 1.8 6.1 2.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 KEP61092.1 - 1.9 7.3 7.4 2.6 6.8 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_subunit PF08597.5 KEP61092.1 - 2.3 7.7 16.6 3.1 7.2 11.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SAPS PF04499.10 KEP61092.1 - 6.9 5.1 7.3 7.7 5.0 5.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SWI-SNF_Ssr4 PF08549.5 KEP61093.1 - 0.027 12.8 1.3 0.031 12.5 0.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) U1snRNP70_N PF12220.3 KEP61093.1 - 0.094 13.0 0.7 0.14 12.4 0.5 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CBFB_NFYA PF02045.10 KEP61093.1 - 8 7.0 9.5 4.8 7.8 3.9 2.4 2 1 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B UQ_con PF00179.21 KEP61094.1 - 4.8e-17 61.6 0.0 6.3e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEP61094.1 - 0.056 13.3 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 KEP61094.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Cation_efflux PF01545.16 KEP61095.1 - 1.3e-59 201.6 11.9 1.6e-59 201.3 8.3 1.1 1 0 0 1 1 1 1 Cation efflux family 7tm_1 PF00001.16 KEP61095.1 - 9.3 5.2 10.2 0.32 10.1 0.3 2.7 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) XPG_I PF00867.13 KEP61096.1 - 2.2e-29 101.3 0.0 5.3e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KEP61096.1 - 7.3e-27 93.5 0.0 3.9e-26 91.2 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KEP61096.1 - 7.7e-06 26.0 0.0 3.1e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Presenilin PF01080.12 KEP61096.1 - 3 6.5 9.4 3.4 6.4 5.8 1.6 1 1 0 1 1 1 0 Presenilin Brix PF04427.13 KEP61098.1 - 3.8e-44 150.6 0.8 6.6e-44 149.8 0.6 1.4 1 0 0 1 1 1 1 Brix domain DUF2415 PF10313.4 KEP61098.1 - 0.11 12.1 0.0 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) PDGF PF00341.12 KEP61099.1 - 0.037 14.1 0.3 0.081 13.0 0.2 1.4 1 0 0 1 1 1 0 PDGF/VEGF domain Abi PF02517.11 KEP61100.1 - 1.6e-15 56.9 7.1 1.6e-15 56.9 4.9 2.5 2 0 0 2 2 2 1 CAAX protease self-immunity ACBP PF00887.14 KEP61102.1 - 2.3e-29 100.8 2.1 2.7e-29 100.6 1.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein UVR PF02151.14 KEP61102.1 - 0.57 9.7 6.3 0.35 10.4 0.7 2.3 2 0 0 2 2 2 0 UvrB/uvrC motif Peptidase_C48 PF02902.14 KEP61106.1 - 7.3e-18 64.9 0.8 2.7e-11 43.5 0.4 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain JAB PF01398.16 KEP61107.1 - 1.8e-09 37.3 0.1 6.2e-08 32.3 0.1 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF159 PF02586.9 KEP61108.1 - 8e-38 130.0 0.0 1.9e-37 128.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised ACR, COG2135 DEAD PF00270.24 KEP61109.1 - 1.9e-37 128.3 1.2 5.1e-35 120.4 0.1 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP61109.1 - 6.3e-17 61.2 0.0 1.7e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEP61109.1 - 6.8e-11 41.5 0.0 1.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KEP61109.1 - 0.067 13.0 0.0 0.48 10.2 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4137 PF13593.1 KEP61109.1 - 0.21 10.6 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) ATP_synt_H PF05493.8 KEP61110.1 - 5.6e-15 55.1 2.5 8.2e-15 54.6 1.7 1.3 1 1 0 1 1 1 1 ATP synthase subunit H DUF2105 PF09878.4 KEP61110.1 - 0.03 13.9 0.3 0.033 13.7 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) DUF4131 PF13567.1 KEP61110.1 - 0.075 12.4 1.0 0.082 12.3 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Syndecan PF01034.15 KEP61110.1 - 0.14 11.8 0.5 0.21 11.2 0.0 1.7 2 1 0 2 2 2 0 Syndecan domain EamA PF00892.15 KEP61110.1 - 0.19 11.7 3.7 0.23 11.4 2.6 1.1 1 0 0 1 1 1 0 EamA-like transporter family VKOR PF07884.9 KEP61110.1 - 0.21 11.4 4.2 0.38 10.5 2.9 1.4 1 1 0 1 1 1 0 Vitamin K epoxide reductase family WD40 PF00400.27 KEP61112.1 - 0.036 13.9 5.3 0.65 9.9 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat EF-hand_8 PF13833.1 KEP61113.1 - 2.2e-07 30.3 1.1 0.014 14.9 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 KEP61113.1 - 2.3e-06 27.6 0.3 0.0039 17.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP61113.1 - 2.1e-05 23.4 0.8 0.0055 15.9 0.1 3.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 KEP61113.1 - 3.2e-05 23.4 0.2 0.0065 16.2 0.2 3.4 3 1 0 3 3 3 1 EF-hand domain EF-hand_9 PF14658.1 KEP61113.1 - 0.018 14.9 0.1 0.71 9.8 0.0 2.5 2 2 0 2 2 2 0 EF-hand domain eIF3_p135 PF12807.2 KEP61115.1 - 1.3e-18 67.4 0.0 3.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KEP61115.1 - 1.5e-11 44.2 0.0 3.3e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KEP61115.1 - 9.2e-10 38.3 4.5 6.7e-08 32.3 0.0 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEP61115.1 - 8.4e-08 31.7 0.1 1.8e-05 24.2 0.0 2.8 2 0 0 2 2 2 1 TPR repeat CLU PF13236.1 KEP61115.1 - 1.4e-06 27.8 0.0 0.014 14.8 0.1 2.4 2 0 0 2 2 2 2 Clustered mitochondria TPR_2 PF07719.12 KEP61115.1 - 0.14 12.1 6.8 2 8.5 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP61115.1 - 0.22 11.1 1.9 36 4.2 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0016 PF01169.14 KEP61116.1 - 6.7e-32 109.4 16.7 4.5e-18 65.1 3.2 2.5 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 7TMR-DISM_7TM PF07695.6 KEP61116.1 - 0.011 15.4 3.1 0.011 15.4 2.1 2.4 2 0 0 2 2 2 0 7TM diverse intracellular signalling SOBP PF15279.1 KEP61116.1 - 0.03 14.7 0.5 0.058 13.7 0.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein TerC PF03741.11 KEP61116.1 - 0.031 13.7 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Integral membrane protein TerC family Rieske PF00355.21 KEP61117.1 - 3.4e-06 26.5 0.0 4.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 KEP61117.1 - 6e-05 22.7 0.0 8.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain FTCD_C PF04961.7 KEP61120.1 - 0.0058 16.0 0.2 0.014 14.8 0.2 1.6 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase TraC_F_IV PF11130.3 KEP61120.1 - 0.27 10.6 2.6 0.57 9.5 1.8 1.5 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Rad60-SLD PF11976.3 KEP61122.1 - 4.1e-25 87.2 0.1 4.8e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KEP61122.1 - 7.8e-09 34.8 0.0 1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.15 KEP61122.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 UBX domain HJURP_C PF12347.3 KEP61122.1 - 0.084 12.4 0.3 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Lysine_decarbox PF03641.9 KEP61123.1 - 1.4e-24 86.4 0.0 2.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase OS-D PF03392.8 KEP61124.1 - 0.092 12.7 1.0 0.44 10.5 0.1 2.6 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Reo_sigmaC PF04582.7 KEP61125.1 - 0.0013 18.0 4.7 0.0013 18.0 3.3 2.8 2 1 0 3 3 3 1 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 KEP61125.1 - 0.0027 17.5 23.7 0.0027 17.5 16.4 3.4 2 1 2 4 4 3 1 Tropomyosin like DivIC PF04977.10 KEP61125.1 - 0.013 14.9 2.2 0.013 14.9 1.5 5.9 3 2 3 6 6 6 0 Septum formation initiator Spc7 PF08317.6 KEP61125.1 - 0.016 13.9 31.8 0.047 12.3 9.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.1 KEP61125.1 - 0.02 15.2 4.6 0.02 15.2 3.2 4.0 3 1 0 3 3 3 0 Snapin/Pallidin Fib_alpha PF08702.5 KEP61125.1 - 0.061 13.4 24.5 0.44 10.6 3.6 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Vac_Fusion PF02346.11 KEP61125.1 - 0.45 9.9 11.0 1.6 8.1 0.1 4.2 4 2 0 4 4 4 0 Chordopoxvirus fusion protein WASH_WAHD PF11945.3 KEP61125.1 - 0.57 9.4 14.3 0.32 10.2 3.3 2.3 2 0 0 2 2 2 0 WAHD domain of WASH complex DUF4201 PF13870.1 KEP61125.1 - 0.6 9.5 25.6 0.011 15.1 7.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) KIP1 PF07765.7 KEP61125.1 - 1.5 8.7 8.9 0.43 10.4 0.1 3.8 3 2 0 3 3 3 0 KIP1-like protein AKNA PF12443.3 KEP61125.1 - 2.1 8.4 14.3 0.65 10.0 0.7 3.7 2 1 2 4 4 4 0 AT-hook-containing transcription factor Mnd1 PF03962.10 KEP61125.1 - 3.3 7.3 37.7 1.5 8.4 6.5 3.5 2 1 1 3 3 3 0 Mnd1 family APG6 PF04111.7 KEP61125.1 - 5 6.0 33.9 1.4 7.8 10.7 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 KEP61125.1 - 7.2 6.8 26.1 2.3 8.4 2.7 4.6 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 KEP61125.1 - 8.1 5.2 29.7 0.14 11.0 3.4 3.3 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 PUF PF00806.14 KEP61126.1 - 5.2e-11 41.3 0.0 0.067 12.6 0.0 6.1 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat DUF3404 PF11884.3 KEP61126.1 - 0.084 11.7 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) DNA_mis_repair PF01119.14 KEP61127.1 - 6.1e-21 74.0 0.0 1.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KEP61127.1 - 3.3e-10 39.7 0.0 6.9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEP61127.1 - 1e-09 38.0 0.0 2.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pex19 PF04614.7 KEP61128.1 - 5.7e-05 22.8 2.7 0.38 10.3 0.1 4.4 4 0 0 4 4 4 3 Pex19 protein family BT1 PF03092.11 KEP61131.1 - 8e-71 239.0 15.7 1.2e-70 238.4 10.9 1.2 1 0 0 1 1 1 1 BT1 family GFO_IDH_MocA_C PF02894.12 KEP61134.1 - 0.24 11.2 1.1 9.3 6.0 0.0 2.9 3 0 0 3 3 3 0 Oxidoreductase family, C-terminal alpha/beta domain DUF605 PF04652.11 KEP61134.1 - 0.65 9.3 12.5 0.78 9.0 8.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF4302 PF14135.1 KEP61135.1 - 0.072 12.4 1.2 3.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4302) Gly_transf_sug PF04488.10 KEP61136.1 - 5.2e-08 33.2 0.0 9.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KEP61136.1 - 0.001 17.6 0.1 0.0014 17.1 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 KEP61136.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein GNT-I PF03071.10 KEP61137.1 - 1.7e-08 33.4 0.0 4.1e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 GNT-I family DUF4407 PF14362.1 KEP61137.1 - 1.7 7.5 4.0 3.1 6.6 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Adaptin_N PF01602.15 KEP61139.1 - 5.7e-87 292.2 0.5 6.8e-87 291.9 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KEP61139.1 - 2.9e-09 37.0 4.0 0.0075 16.5 0.1 5.0 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 KEP61139.1 - 9.2e-06 25.3 6.6 0.09 12.9 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat B2-adapt-app_C PF09066.5 KEP61139.1 - 0.0019 18.0 0.0 0.0059 16.4 0.0 1.8 1 1 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Cnd1 PF12717.2 KEP61139.1 - 0.0056 16.5 0.4 0.11 12.3 0.0 3.2 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KEP61139.1 - 0.98 9.9 9.2 1.6 9.2 0.1 5.3 4 2 3 7 7 7 0 HEAT-like repeat Acyl-CoA_dh_1 PF00441.19 KEP61140.1 - 7.6e-44 149.4 2.2 1.2e-43 148.7 1.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEP61140.1 - 1.9e-28 99.3 0.0 6.8e-28 97.5 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEP61140.1 - 1.8e-20 73.5 0.5 3.4e-20 72.6 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEP61140.1 - 8.6e-16 57.1 0.1 1.5e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACT_5 PF13710.1 KEP61142.1 - 0.00025 20.7 2.6 3.3 7.5 0.0 3.8 1 1 3 4 4 4 4 ACT domain Peptidase_M50 PF02163.17 KEP61143.1 - 2e-11 43.2 5.8 3e-11 42.6 4.0 1.2 1 0 0 1 1 1 1 Peptidase family M50 GSHPx PF00255.14 KEP61144.1 - 1.6e-23 82.1 0.0 2.4e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KEP61144.1 - 0.0034 17.0 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Tetraspannin PF00335.15 KEP61145.1 - 0.0003 20.1 20.4 0.019 14.2 9.7 2.3 2 0 0 2 2 2 2 Tetraspanin family DUF2330 PF10092.4 KEP61145.1 - 0.12 11.2 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) DUF4131 PF13567.1 KEP61145.1 - 1.7 8.0 9.9 0.34 10.2 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) GSHPx PF00255.14 KEP61146.1 - 1.3e-19 69.6 0.1 1.9e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KEP61146.1 - 0.036 13.7 0.1 0.097 12.3 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family DEAD PF00270.24 KEP61147.1 - 1.7e-28 99.2 0.0 4.3e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP61147.1 - 7.8e-23 80.1 0.0 1.9e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP61147.1 - 0.00047 20.0 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ins145_P3_rec PF08709.6 KEP61148.1 - 0.029 13.4 0.1 0.18 10.7 0.0 2.3 2 1 1 3 3 3 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Pkinase PF00069.20 KEP61149.1 - 1.7e-24 86.4 0.0 4.4e-24 85.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEP61149.1 - 4.7e-23 81.5 0.0 7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KEP61149.1 - 3.5e-10 39.3 0.0 1.2e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KEP61149.1 - 0.088 11.8 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEP61149.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1625 PF07787.7 KEP61150.1 - 1.6e-19 70.1 0.0 2.7e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) Wbp11 PF09429.5 KEP61151.1 - 0.21 11.5 10.4 0.048 13.6 2.5 2.5 1 1 1 2 2 2 0 WW domain binding protein 11 COG6 PF06419.6 KEP61151.1 - 0.23 9.5 3.4 0.32 9.0 2.3 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 DUF904 PF06005.7 KEP61151.1 - 0.48 10.7 10.5 2.2 8.6 2.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 KEP61151.1 - 0.68 8.9 8.6 1 8.3 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KEP61151.1 - 3.6 7.1 8.2 6.7 6.2 5.7 1.4 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 KEP61151.1 - 5.1 7.0 5.1 10 6.1 3.3 1.6 1 1 0 1 1 1 0 Haemolysin XhlA Ribosomal_L31e PF01198.14 KEP61152.1 - 4.4e-20 71.1 1.6 5.7e-20 70.7 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_S2 PF00318.15 KEP61154.1 - 7.2e-45 152.8 0.1 2.5e-21 75.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 RCC1 PF00415.13 KEP61156.1 - 2.7e-35 120.3 24.5 1.8e-11 44.0 0.1 8.3 9 1 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP61156.1 - 1.6e-15 56.2 22.3 0.0007 19.1 4.2 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat PRP38 PF03371.10 KEP61158.1 - 4.4e-56 189.2 0.0 6.7e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 PRP38 family PI3_PI4_kinase PF00454.22 KEP61159.1 - 4.6e-21 75.3 0.0 2.2e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KEP61159.1 - 0.15 11.4 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 FATC domain Endonuc-FokI_C PF09254.6 KEP61159.1 - 5.7 5.9 0.1 10 5.1 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Colicin PF01024.14 KEP61159.1 - 8.3 5.9 0.0 16 4.9 0.0 1.4 1 0 0 1 1 1 0 Colicin pore forming domain MPP6 PF10175.4 KEP61160.1 - 0.044 14.1 0.3 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 M-phase phosphoprotein 6 PAS_11 PF14598.1 KEP61160.1 - 0.084 12.8 0.4 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 PAS domain ALMS_motif PF15309.1 KEP61160.1 - 2.9 7.7 11.6 1.4 8.7 2.6 2.2 2 0 0 2 2 2 0 ALMS motif Pantoate_ligase PF02569.10 KEP61161.1 - 8e-52 175.7 0.0 1.6e-25 89.4 0.0 2.1 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase CN_hydrolase PF00795.17 KEP61162.1 - 8.8e-18 64.3 0.0 3.5e-17 62.3 0.0 1.8 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase DevR PF01905.11 KEP61162.1 - 0.034 13.0 0.3 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated negative auto-regulator DevR/Csa2 RNase_Zc3h12a PF11977.3 KEP61163.1 - 1.4e-27 96.4 0.0 2.8e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain EST1_DNA_bind PF10373.4 KEP61163.1 - 8.2e-07 28.5 0.0 2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PhoD PF09423.5 KEP61165.1 - 2.3e-12 46.2 0.0 3.6e-11 42.3 0.0 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase Las1 PF04031.8 KEP61166.1 - 1.5e-28 99.4 0.0 2.4e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Las1-like Methyltransf_11 PF08241.7 KEP61167.1 - 5.3e-07 30.0 0.0 0.00054 20.3 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KEP61167.1 - 0.0088 15.6 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP61167.1 - 0.016 15.7 0.0 0.18 12.3 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M14 PF00246.19 KEP61169.1 - 2.5e-18 66.7 0.0 4.4e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase PP2C PF00481.16 KEP61171.1 - 1.5e-11 44.2 0.2 9.4e-05 21.9 0.1 3.1 3 0 0 3 3 3 3 Protein phosphatase 2C N2227 PF07942.7 KEP61172.1 - 2e-62 210.6 0.0 2.8e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_18 PF12847.2 KEP61172.1 - 0.091 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KEP61172.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FAM74 PF15026.1 KEP61173.1 - 0.42 10.2 4.0 0.46 10.1 0.2 2.0 2 0 0 2 2 2 0 FAM74 protein Metallophos PF00149.23 KEP61174.1 - 1.2e-39 135.7 1.1 1.7e-39 135.3 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thiolase_N PF00108.18 KEP61175.1 - 9.2e-83 277.2 0.4 1.3e-82 276.7 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEP61175.1 - 9.8e-42 141.2 1.6 1.8e-40 137.1 0.1 2.7 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KEP61175.1 - 0.0021 17.6 2.0 0.03 13.9 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PRA1 PF03208.14 KEP61177.1 - 0.029 13.6 0.8 0.042 13.2 0.5 1.2 1 0 0 1 1 1 0 PRA1 family protein DUF1469 PF07332.6 KEP61177.1 - 0.081 12.6 1.5 0.13 12.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF898 PF05987.8 KEP61177.1 - 0.13 11.1 0.9 0.15 10.9 0.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) SAG PF04092.8 KEP61178.1 - 5.5e-39 133.3 6.2 5.3e-20 72.0 1.8 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP61179.1 - 4.2e-44 149.9 19.9 4.3e-23 82.0 3.3 2.1 2 0 0 2 2 2 2 SRS domain PNTB PF02233.11 KEP61181.1 - 3.5e-171 570.0 15.8 3.5e-171 570.0 10.9 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KEP61181.1 - 8.4e-46 155.5 0.0 1.5e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3814 PF12769.2 KEP61181.1 - 5.4e-28 96.9 6.4 5.4e-28 96.9 4.4 4.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3814) AlaDh_PNT_N PF05222.10 KEP61181.1 - 8.5e-24 84.0 1.7 1.2e-19 70.6 0.1 3.1 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.15 KEP61181.1 - 0.0029 17.7 0.3 0.56 10.3 0.0 2.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KEP61181.1 - 0.01 15.7 0.7 0.12 12.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KEP61181.1 - 0.14 11.3 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2678 PF10856.3 KEP61181.1 - 1.9 8.2 6.3 0.55 9.9 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Exo_endo_phos PF03372.18 KEP61182.1 - 3e-13 50.2 0.0 6.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF591 PF04569.9 KEP61183.1 - 0.18 11.8 5.7 0.28 11.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function BHD_1 PF10403.4 KEP61184.1 - 7.4e-11 41.3 0.0 1.3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 KEP61184.1 - 9.5e-10 38.0 0.0 2.7e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 KEP61184.1 - 4e-07 29.5 0.2 9.8e-05 21.7 0.0 3.2 2 0 0 2 2 2 2 Rad4 transglutaminase-like domain BHD_2 PF10404.4 KEP61184.1 - 1.3e-05 25.3 4.6 0.00032 20.9 0.8 4.8 5 0 0 5 5 5 2 Rad4 beta-hairpin domain 2 IncA PF04156.9 KEP61185.1 - 0.0017 17.9 12.1 0.0036 16.9 0.4 3.3 3 0 0 3 3 3 1 IncA protein HEAT_EZ PF13513.1 KEP61185.1 - 0.049 14.1 3.0 0.061 13.8 0.2 2.7 2 0 0 2 2 2 0 HEAT-like repeat DUF2730 PF10805.3 KEP61185.1 - 4.5 7.0 6.8 3 7.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Cluap1 PF10234.4 KEP61187.1 - 0.0054 15.9 0.7 0.0096 15.1 0.5 1.3 1 0 0 1 1 1 1 Clusterin-associated protein-1 Pkinase PF00069.20 KEP61188.1 - 2.7e-34 118.5 0.0 5.5e-32 110.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61188.1 - 4.5e-23 81.6 0.0 5.7e-21 74.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EDR1 PF14381.1 KEP61188.1 - 1.3e-15 57.5 0.0 2.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Pox_ser-thr_kin PF05445.6 KEP61188.1 - 3.3 6.3 0.0 5 5.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BLVR PF06375.6 KEP61189.1 - 0.00044 20.1 4.8 0.00049 19.9 3.3 1.1 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 KEP61189.1 - 0.0096 15.4 9.3 0.011 15.2 6.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein OAD_gamma PF04277.8 KEP61189.1 - 0.018 15.3 1.9 0.024 15.0 1.3 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FancD2 PF14631.1 KEP61189.1 - 0.042 10.9 0.3 0.044 10.8 0.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Di19_C PF14571.1 KEP61189.1 - 0.043 14.1 0.0 0.051 13.8 0.0 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal FAM176 PF14851.1 KEP61189.1 - 0.065 12.9 0.1 0.071 12.7 0.1 1.1 1 0 0 1 1 1 0 FAM176 family Med19 PF10278.4 KEP61189.1 - 0.4 10.3 13.0 0.46 10.1 9.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNase_H2-Ydr279 PF09468.5 KEP61189.1 - 0.48 9.5 5.4 0.53 9.4 3.7 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Pox_Ag35 PF03286.9 KEP61189.1 - 0.56 9.7 9.3 0.65 9.4 6.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nro1 PF12753.2 KEP61189.1 - 0.57 9.0 6.7 0.73 8.7 4.6 1.0 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 PBP_sp32 PF07222.7 KEP61189.1 - 0.59 9.2 3.6 0.7 9.0 2.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NARP1 PF12569.3 KEP61189.1 - 3.3 6.3 9.5 3.8 6.1 6.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.5 KEP61189.1 - 5.9 6.6 10.9 7.6 6.3 7.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Gtr1_RagA PF04670.7 KEP61190.1 - 1.2e-26 93.3 0.0 2.4e-23 82.4 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF1510 PF07423.6 KEP61190.1 - 2.8 7.2 14.9 4.5 6.5 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 KEP61190.1 - 3 6.1 20.5 4.2 5.7 14.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 KEP61190.1 - 3.6 5.9 18.3 5.1 5.4 12.7 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 KEP61190.1 - 5.2 4.6 6.5 6.9 4.2 4.5 1.1 1 0 0 1 1 1 0 Ycf1 RNA_GG_bind PF10258.4 KEP61191.1 - 3.6e-17 61.8 0.0 6e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 PHAX RNA-binding domain MIP-T3 PF10243.4 KEP61192.1 - 0.26 9.6 40.3 0.32 9.3 27.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-DHHC PF01529.15 KEP61192.1 - 1.9 7.8 4.0 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 DHHC palmitoyltransferase DnaJ PF00226.26 KEP61193.1 - 1.8e-23 81.9 0.6 4.4e-23 80.7 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 KEP61193.1 - 2.7e-08 33.7 4.1 7.8e-07 29.0 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEP61193.1 - 1.4e-07 31.4 5.1 3e-06 27.1 0.5 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KEP61193.1 - 1.1e-05 25.4 7.6 0.028 14.7 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEP61193.1 - 3.2e-05 23.9 2.5 0.054 13.8 0.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEP61193.1 - 3.8e-05 23.7 14.3 0.0017 18.4 0.2 3.5 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KEP61193.1 - 0.00024 20.8 8.2 0.042 13.7 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEP61193.1 - 0.088 13.1 2.0 2.1 8.7 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-DBF PF07535.7 KEP61193.1 - 0.21 11.2 9.5 1.3 8.7 3.1 3.0 2 1 0 2 2 2 0 DBF zinc finger Zn-ribbon_8 PF09723.5 KEP61193.1 - 0.46 10.4 3.7 11 6.0 0.2 3.0 2 0 0 2 2 2 0 Zinc ribbon domain SNARE_assoc PF09335.6 KEP61194.1 - 1.8e-16 60.4 5.2 1.8e-16 60.4 3.6 2.1 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF221 PF02714.10 KEP61195.1 - 2.7e-09 36.3 16.1 0.00012 21.1 0.1 3.9 2 2 2 4 4 4 3 Domain of unknown function DUF221 zf-DHHC PF01529.15 KEP61196.1 - 2.6e-31 108.3 5.3 2.6e-31 108.3 3.7 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase GTP_EFTU PF00009.22 KEP61197.1 - 7.9e-51 172.1 0.1 1.2e-50 171.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KEP61197.1 - 2e-16 59.6 0.0 3.9e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KEP61197.1 - 4.6e-06 26.5 0.1 7.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEP61197.1 - 0.0027 18.1 0.1 0.0053 17.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KEP61197.1 - 0.013 14.7 0.0 0.048 12.9 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.11 KEP61197.1 - 0.014 14.4 0.1 0.081 12.0 0.0 1.9 1 1 0 1 1 1 0 AIG1 family Dynamin_N PF00350.18 KEP61197.1 - 0.074 12.8 0.3 0.68 9.7 0.0 2.4 2 1 0 2 2 2 0 Dynamin family BOP1NT PF08145.7 KEP61198.1 - 2.3e-89 299.6 0.2 4.1e-89 298.7 0.1 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KEP61198.1 - 3.9e-20 70.9 6.1 8.8e-06 25.4 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KEP61198.1 - 0.022 14.2 0.0 9.2 5.8 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ENTH PF01417.15 KEP61201.1 - 0.00034 20.4 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Maf PF02545.9 KEP61203.1 - 1.6e-43 148.0 0.0 5.7e-39 133.2 0.0 2.5 2 1 0 2 2 2 2 Maf-like protein NACHT PF05729.7 KEP61203.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF4643 PF15485.1 KEP61203.1 - 0.51 9.7 6.6 0.068 12.6 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4643) Pkinase PF00069.20 KEP61204.1 - 2.2e-77 259.7 0.2 2.9e-77 259.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61204.1 - 5.8e-42 143.5 0.0 7.7e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP61204.1 - 1.3e-27 92.9 8.5 1e-06 27.5 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP61204.1 - 2.3e-24 85.3 9.8 1.5e-10 41.0 0.5 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KEP61204.1 - 6.8e-23 78.4 4.4 5.1e-05 22.8 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEP61204.1 - 2.5e-22 77.1 6.6 2.2e-05 23.5 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KEP61204.1 - 1.3e-17 63.1 10.9 0.00038 19.9 0.3 4.5 1 1 3 4 4 4 4 EF-hand domain pair Kinase-like PF14531.1 KEP61204.1 - 3.9e-06 26.0 0.1 0.0016 17.4 0.0 2.8 2 1 0 2 2 2 2 Kinase-like SPARC_Ca_bdg PF10591.4 KEP61204.1 - 1.2e-05 25.3 0.9 0.032 14.2 0.0 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 KEP61204.1 - 1.5e-05 24.1 0.1 5.1e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 KEP61204.1 - 0.00011 21.8 7.8 0.02 14.6 0.5 3.9 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand APH PF01636.18 KEP61204.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEP61204.1 - 0.021 14.1 1.0 0.076 12.3 0.0 2.3 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL EF-hand_10 PF14788.1 KEP61204.1 - 0.1 12.2 1.3 2.7 7.7 0.0 3.4 5 0 0 5 5 5 0 EF hand NCD1 PF04904.8 KEP61204.1 - 0.16 11.7 0.8 11 5.8 0.0 2.7 2 1 0 2 2 2 0 NAB conserved region 1 (NCD1) VCBS PF13517.1 KEP61205.1 - 1e-20 73.8 11.5 2.4e-05 24.5 1.2 7.6 6 1 1 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEP61205.1 - 3.8e-18 64.6 5.5 0.0013 18.3 0.0 7.0 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 KEP61205.1 - 9.8e-07 28.3 0.0 0.15 11.5 0.0 4.8 5 0 0 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region DUF2562 PF10814.3 KEP61208.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) DUF3328 PF11807.3 KEP61209.1 - 0.00058 19.6 0.1 0.0059 16.3 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF3328) DUF4229 PF14012.1 KEP61209.1 - 0.32 10.9 0.1 0.32 10.9 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) Phasin PF05597.6 KEP61211.1 - 6.5e-05 22.7 1.8 0.00037 20.2 1.3 2.1 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3782 PF12644.2 KEP61211.1 - 0.0087 15.8 0.6 0.1 12.4 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3782) DUF3138 PF11336.3 KEP61211.1 - 0.026 12.6 1.1 0.034 12.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Uds1 PF15456.1 KEP61211.1 - 0.056 13.4 3.8 0.089 12.7 2.0 2.1 1 1 0 1 1 1 0 Up-regulated During Septation Spc24 PF08286.6 KEP61211.1 - 0.1 12.2 2.0 0.17 11.5 0.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cob_adeno_trans PF01923.13 KEP61211.1 - 0.31 10.8 2.8 0.28 10.9 0.2 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Seryl_tRNA_N PF02403.17 KEP61211.1 - 2.6 8.1 6.4 6.8 6.7 0.4 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HisKA_2 PF07568.7 KEP61212.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase DNA_pol_A PF00476.15 KEP61213.1 - 5.4e-64 216.1 0.0 8.9e-57 192.4 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase family A DUF3410 PF11890.3 KEP61214.1 - 0.036 13.7 0.6 0.051 13.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Pkinase PF00069.20 KEP61216.1 - 1.1e-49 168.9 0.0 3.8e-20 72.1 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61216.1 - 9e-26 90.4 0.0 1.9e-14 53.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_6 PF13405.1 KEP61216.1 - 7.9e-08 31.5 6.6 0.0041 16.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KEP61216.1 - 1.2e-07 30.5 7.7 0.00099 18.2 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KEP61216.1 - 2.1e-05 24.5 4.6 2.1e-05 24.5 3.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair PH PF00169.24 KEP61216.1 - 2.6e-05 24.3 0.0 0.00015 21.8 0.0 2.4 2 1 0 2 2 2 1 PH domain EF-hand_8 PF13833.1 KEP61216.1 - 0.0013 18.2 6.7 0.12 12.0 1.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KEP61216.1 - 0.019 14.2 0.2 0.019 14.2 0.1 2.7 2 0 0 2 2 2 0 EF hand FYVE PF01363.16 KEP61217.1 - 3.4e-17 62.0 10.9 3.4e-17 62.0 7.6 2.0 2 0 0 2 2 2 1 FYVE zinc finger Atg14 PF10186.4 KEP61217.1 - 0.0026 16.7 6.2 0.0047 15.9 4.3 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KEP61217.1 - 0.03 13.9 16.6 0.015 14.8 8.4 2.1 2 0 0 2 2 2 0 IncA protein FUSC PF04632.7 KEP61217.1 - 1.4 7.2 10.7 2.2 6.6 7.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 KEP61217.1 - 6.1 6.6 18.6 1.2 8.9 9.1 2.4 2 1 0 2 2 2 0 Tropomyosin like SlyX PF04102.7 KEP61217.1 - 7.2 7.0 9.1 2.9 8.3 1.6 2.6 2 0 0 2 2 2 0 SlyX PIN PF01850.16 KEP61218.1 - 0.022 15.1 0.0 0.033 14.5 0.0 1.4 1 1 0 1 1 1 0 PIN domain DUF1908 PF08926.6 KEP61218.1 - 0.072 11.8 0.0 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) CbiN PF02553.10 KEP61218.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 Cobalt transport protein component CbiN Pkinase PF00069.20 KEP61219.1 - 2.6e-62 210.3 0.0 1.3e-51 175.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61219.1 - 3.4e-27 95.1 0.0 3.5e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP61219.1 - 1.5e-15 55.2 2.3 0.00015 20.7 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KEP61219.1 - 4.3e-15 55.5 4.4 2.7e-07 30.6 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP61219.1 - 3.3e-12 45.1 3.1 0.00032 20.3 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KEP61219.1 - 4.5e-08 32.0 0.2 0.0026 17.0 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KEP61219.1 - 1.3e-07 31.1 2.8 0.14 11.8 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair Kdo PF06293.9 KEP61219.1 - 0.00025 20.1 0.1 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP61219.1 - 0.0011 18.8 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP61219.1 - 0.065 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GlnE PF03710.10 KEP61219.1 - 0.32 10.2 1.9 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase INO80_Ies4 PF08193.6 KEP61220.1 - 0.0032 17.4 0.1 0.0037 17.2 0.1 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 HILPDA PF15220.1 KEP61220.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated TBCA PF02970.11 KEP61221.1 - 7.7e-25 86.7 2.4 1.1e-24 86.3 1.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A Kinesin-relat_1 PF12711.2 KEP61221.1 - 0.072 13.4 1.5 0.11 12.9 0.6 1.7 2 0 0 2 2 2 0 Kinesin motor NUC153 PF08159.7 KEP61222.1 - 0.0058 16.1 0.5 0.01 15.3 0.4 1.4 1 0 0 1 1 1 1 NUC153 domain Vps54 PF07928.7 KEP61223.1 - 4.7e-12 46.2 0.2 1.3e-11 44.8 0.1 1.8 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KEP61223.1 - 2.2e-05 23.5 0.1 3.7e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) XPC-binding PF09280.6 KEP61224.1 - 9.2e-24 82.6 8.5 1.8e-23 81.7 5.9 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 KEP61224.1 - 6.2e-23 79.9 5.1 3.7e-12 45.7 0.0 2.8 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 KEP61224.1 - 1.4e-12 46.8 0.0 2.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 KEP61224.1 - 1.2e-05 25.1 0.1 2.1e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RuvA_C PF07499.8 KEP61224.1 - 0.0011 19.1 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 2 RuvA, C-terminal domain DUF2407 PF10302.4 KEP61224.1 - 0.013 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MSA-2c PF12238.3 KEP61224.1 - 0.019 14.6 1.4 0.037 13.7 1.0 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3173 PF11372.3 KEP61224.1 - 0.037 13.6 0.0 0.81 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Rad60-SLD PF11976.3 KEP61224.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Stm1_N PF09598.5 KEP61224.1 - 0.12 13.1 2.3 0.42 11.3 1.6 2.0 1 0 0 1 1 1 0 Stm1 MSP1_C PF07462.6 KEP61224.1 - 1 7.6 6.8 1.5 7.1 4.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RAP1 PF07218.6 KEP61224.1 - 3.9 5.4 4.5 5.1 5.0 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NDK PF00334.14 KEP61225.1 - 2.7e-55 185.8 0.0 3.1e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NUFIP1 PF10453.4 KEP61225.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Sugarporin_N PF11471.3 KEP61227.1 - 0.00021 20.8 2.2 0.00042 19.8 1.5 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension GAS PF13851.1 KEP61227.1 - 0.13 11.4 0.2 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 KEP61227.1 - 0.2 10.6 0.3 0.26 10.2 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF544 PF04424.8 KEP61230.1 - 1.2e-15 57.3 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF1546 PF07571.8 KEP61231.1 - 5.6e-06 26.3 0.9 1.1e-05 25.4 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1546) TAF PF02969.12 KEP61231.1 - 0.043 13.7 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Transformer PF06495.6 KEP61231.1 - 3 7.6 16.2 9.8 6.0 11.2 1.8 1 0 0 1 1 1 0 Fruit fly transformer protein TerD PF02342.13 KEP61232.1 - 6.5e-14 51.6 0.0 1.8e-13 50.2 0.0 1.8 1 1 1 2 2 2 1 TerD domain DUF1395 PF07160.7 KEP61233.1 - 0.063 12.7 0.1 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) DUF911 PF06023.7 KEP61233.1 - 0.11 11.6 0.7 2.9 7.0 0.0 2.1 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF911) HEAT_2 PF13646.1 KEP61234.1 - 0.02 15.1 0.2 0.14 12.4 0.0 2.4 2 1 1 3 3 3 0 HEAT repeats ADIP PF11559.3 KEP61235.1 - 0.0066 16.3 8.9 0.0085 16.0 6.1 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding HOOK PF05622.7 KEP61235.1 - 0.0074 14.1 3.3 0.0093 13.8 2.3 1.1 1 0 0 1 1 1 1 HOOK protein APG6 PF04111.7 KEP61235.1 - 0.0087 15.1 8.2 0.011 14.8 5.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF842 PF05811.8 KEP61235.1 - 0.0089 15.4 0.3 0.012 15.0 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Metal_resist PF13801.1 KEP61235.1 - 0.03 14.3 0.4 0.044 13.7 0.3 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Seryl_tRNA_N PF02403.17 KEP61235.1 - 0.039 13.9 6.4 0.055 13.4 4.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KEP61235.1 - 0.045 13.4 3.6 0.057 13.0 2.5 1.1 1 0 0 1 1 1 0 Mnd1 family CorA PF01544.13 KEP61235.1 - 0.052 12.5 5.2 0.065 12.2 3.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 KEP61235.1 - 0.07 12.7 7.8 0.092 12.3 5.4 1.2 1 0 0 1 1 1 0 IncA protein Mer2 PF09074.5 KEP61235.1 - 0.078 12.8 4.1 0.089 12.7 1.8 1.7 1 1 1 2 2 2 0 Mer2 OmpH PF03938.9 KEP61235.1 - 0.085 12.7 3.3 0.11 12.4 2.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) EzrA PF06160.7 KEP61235.1 - 0.092 10.9 6.7 0.11 10.6 4.7 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA StbA PF06406.6 KEP61235.1 - 0.11 11.4 1.4 0.12 11.3 1.0 1.1 1 0 0 1 1 1 0 StbA protein DUF3086 PF11285.3 KEP61235.1 - 0.12 11.1 2.2 0.15 10.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) V_ATPase_I PF01496.14 KEP61235.1 - 0.19 9.5 2.5 0.21 9.3 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2570 PF10828.3 KEP61235.1 - 0.22 11.1 4.7 0.32 10.5 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF972 PF06156.8 KEP61235.1 - 0.33 11.3 3.2 0.52 10.6 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 KEP61235.1 - 0.75 8.1 5.4 0.89 7.8 3.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain COG2 PF06148.6 KEP61235.1 - 1.2 8.9 5.4 5.1 6.9 3.7 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GrpE PF01025.14 KEP61235.1 - 1.4 8.4 6.4 1.9 8.0 4.1 1.4 1 1 0 1 1 1 0 GrpE DivIC PF04977.10 KEP61235.1 - 1.5 8.3 9.4 5.6 6.5 6.5 1.9 1 1 1 2 2 2 0 Septum formation initiator DivIVA PF05103.8 KEP61235.1 - 1.8 8.6 8.8 8.4 6.4 5.3 2.0 1 1 1 2 2 2 0 DivIVA protein Phytochelatin_C PF09328.5 KEP61235.1 - 1.8 7.9 5.6 0.94 8.9 2.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1984) CCDC-167 PF15188.1 KEP61235.1 - 3.5 7.6 8.4 2.1 8.3 3.9 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Got1 PF04178.7 KEP61236.1 - 5.2e-18 65.2 11.0 6e-18 65.0 7.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 KEP61236.1 - 0.16 11.9 14.0 0.15 12.0 7.4 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) C2 PF00168.25 KEP61237.1 - 5.9e-24 83.7 2.0 2.7e-08 33.5 0.0 5.1 5 0 0 5 5 5 3 C2 domain RAP PF08373.5 KEP61238.1 - 0.00013 21.6 0.0 0.00046 19.9 0.0 1.9 2 0 0 2 2 2 1 RAP domain SAG PF04092.8 KEP61239.1 - 3.8e-41 140.3 12.7 2.6e-28 98.8 1.8 2.2 2 0 0 2 2 2 2 SRS domain Pilin PF00114.14 KEP61239.1 - 0.48 11.1 8.7 0.14 12.8 1.9 2.6 2 1 0 2 2 2 0 Pilin (bacterial filament) DivIC PF04977.10 KEP61240.1 - 0.73 9.3 4.4 0.35 10.3 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator SET PF00856.23 KEP61241.1 - 4.2e-24 85.6 1.2 1.2e-22 80.9 0.1 4.2 2 0 0 2 2 2 1 SET domain Peptidase_M13_N PF05649.8 KEP61244.1 - 6.4e-95 318.4 0.1 9.2e-95 317.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KEP61244.1 - 1.2e-41 142.2 0.0 5.1e-20 71.5 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M48 PF01435.13 KEP61244.1 - 0.041 13.4 0.5 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M48 WD-3 PF09765.4 KEP61245.1 - 0.013 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 WD-repeat region zf-UBR PF02207.15 KEP61246.1 - 7.6e-17 60.8 11.0 7.6e-17 60.8 7.6 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) DUF779 PF05610.6 KEP61246.1 - 0.22 11.5 0.5 0.67 10.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF779) ISG65-75 PF11727.3 KEP61247.1 - 0.0012 17.9 0.5 0.002 17.2 0.4 1.4 1 0 0 1 1 1 1 Invariant surface glycoprotein SICA_alpha PF12887.2 KEP61247.1 - 0.0013 18.5 0.8 0.082 12.6 0.0 2.1 2 0 0 2 2 2 2 SICA extracellular alpha domain HrpE PF06188.7 KEP61247.1 - 0.0028 17.4 0.3 0.0028 17.4 0.2 1.8 2 0 0 2 2 2 1 HrpE/YscL/FliH and V-type ATPase subunit E Apolipoprotein PF01442.13 KEP61247.1 - 0.021 14.3 1.5 0.16 11.4 1.0 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 KEP61247.1 - 0.089 12.6 0.8 3.1 7.6 0.0 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 KEP61248.1 - 5.8e-42 140.1 15.9 2.8e-10 39.6 0.2 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Utp12 PF04003.7 KEP61248.1 - 4.6e-08 32.9 0.3 8.9e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family SGL PF08450.7 KEP61248.1 - 0.068 12.5 0.0 4.2 6.6 0.0 2.9 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Cytochrom_D1 PF02239.11 KEP61248.1 - 0.15 10.3 0.0 1.7 6.8 0.0 2.6 3 0 0 3 3 3 0 Cytochrome D1 heme domain Ubie_methyltran PF01209.13 KEP61249.1 - 6.7e-79 264.2 0.0 2.4e-54 183.9 0.0 2.8 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KEP61249.1 - 6.6e-16 58.5 0.0 2.9e-13 50.1 0.0 2.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP61249.1 - 1.5e-09 37.6 0.0 5.4e-05 22.8 0.0 3.3 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 KEP61249.1 - 7.6e-09 35.8 0.1 1.5e-06 28.4 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP61249.1 - 8e-09 35.4 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP61249.1 - 4.6e-07 30.2 0.0 2.5e-05 24.6 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP61249.1 - 6.1e-06 26.7 0.0 0.033 14.7 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KEP61249.1 - 1.1e-05 25.4 0.0 3.3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KEP61249.1 - 0.0011 18.5 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase DUF908 PF06012.7 KEP61250.1 - 1.2e-100 337.0 0.0 3.1e-99 332.4 0.0 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) HECT PF00632.20 KEP61250.1 - 1.6e-91 306.7 0.0 2.3e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 KEP61250.1 - 1.5e-19 69.9 9.8 1e-17 63.9 4.0 4.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4414) DUF913 PF06025.7 KEP61250.1 - 2e-19 69.6 7.3 7.3e-10 38.1 0.0 4.3 4 0 0 4 4 4 2 Domain of Unknown Function (DUF913) UBA PF00627.26 KEP61250.1 - 1.3e-07 31.2 0.4 3.8e-07 29.7 0.3 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DUF46 PF01864.12 KEP61250.1 - 2.5 7.9 0.1 5.3 6.8 0.1 1.4 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 Oxidored_molyb PF00174.14 KEP61251.1 - 6.6e-61 204.6 0.0 9.6e-61 204.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KEP61251.1 - 3.3e-21 75.3 0.0 5.7e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 KEP61251.1 - 2.8e-16 59.0 0.1 4.8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_11 PF13414.1 KEP61252.1 - 4.4e-07 29.4 0.2 4.4e-07 29.4 0.1 2.6 2 1 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 KEP61252.1 - 3.3e-06 26.4 0.2 0.00026 20.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEP61252.1 - 0.00029 20.5 0.4 0.056 13.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.4 KEP61252.1 - 0.024 13.2 0.7 0.033 12.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) DUF4448 PF14610.1 KEP61252.1 - 0.095 12.1 0.8 0.14 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) YqfQ PF14181.1 KEP61252.1 - 0.48 10.4 4.0 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 YqfQ-like protein Pkinase PF00069.20 KEP61255.1 - 3.3e-54 183.7 0.0 4.4e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61255.1 - 3.4e-22 78.7 0.0 4.8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP61255.1 - 2.2e-13 48.4 5.8 3.9e-06 25.7 0.8 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KEP61255.1 - 1.3e-09 38.0 6.8 3.7e-06 26.9 2.2 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEP61255.1 - 2.8e-09 36.4 5.6 1.7e-06 27.5 0.5 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP61255.1 - 1.4e-07 30.7 8.7 0.042 13.7 0.1 4.7 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KEP61255.1 - 2.4e-06 26.6 2.5 0.02 14.2 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 KEP61255.1 - 0.021 14.5 1.3 0.073 12.8 0.3 2.3 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 KEP61255.1 - 0.039 12.9 0.0 0.082 11.8 0.0 1.5 2 0 0 2 2 2 0 Kinase-like cNMP_binding PF00027.24 KEP61257.1 - 9.9e-17 60.5 0.0 3.2e-08 33.2 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RNase_H2-Ydr279 PF09468.5 KEP61257.1 - 0.18 11.0 6.1 0.28 10.3 3.6 1.8 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) MtrC PF04211.8 KEP61257.1 - 5.6 5.9 0.0 8.8 5.2 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C ClpS PF02617.12 KEP61258.1 - 1.9e-15 56.3 0.1 4.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS TPR_11 PF13414.1 KEP61259.1 - 3.2e-08 33.1 0.0 7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KEP61259.1 - 3.3e-05 23.4 0.0 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEP61259.1 - 0.0002 20.8 0.1 0.61 9.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat CS PF04969.11 KEP61259.1 - 0.0011 19.5 0.0 0.0034 17.9 0.0 1.8 2 0 0 2 2 2 1 CS domain Elongin_A PF06881.6 KEP61259.1 - 0.0043 17.4 7.4 0.02 15.2 4.3 2.4 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TPR_16 PF13432.1 KEP61259.1 - 0.036 14.7 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3395 PF11875.3 KEP61259.1 - 0.064 12.8 3.1 0.12 12.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Ponericin PF07442.6 KEP61259.1 - 0.17 11.7 0.5 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Ponericin TPR_11 PF13414.1 KEP61260.1 - 3e-05 23.5 3.1 0.13 11.9 0.3 3.6 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KEP61260.1 - 0.00083 18.8 0.5 16 5.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.2 KEP61260.1 - 0.0016 18.2 0.9 0.083 12.7 0.0 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.1 KEP61260.1 - 0.067 13.5 1.7 30 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KEP61260.1 - 0.11 12.3 1.1 38 4.2 0.0 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 KEP61260.1 - 0.59 10.0 3.3 4.6 7.2 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEP61260.1 - 0.79 10.4 4.8 9.4 7.0 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP61260.1 - 5.4 7.9 6.1 7.3 7.5 0.0 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat HA PF03457.9 KEP61262.1 - 0.042 13.9 6.3 0.11 12.6 0.7 2.9 2 0 0 2 2 2 0 Helicase associated domain DUF2829 PF11195.3 KEP61262.1 - 0.18 12.3 4.0 4.6 7.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2829) DHQ_synthase PF01761.15 KEP61263.1 - 2.5e-70 236.3 0.6 1.9e-42 144.9 0.0 2.6 3 0 0 3 3 3 2 3-dehydroquinate synthase EPSP_synthase PF00275.15 KEP61263.1 - 2.3e-36 125.1 2.9 1.5e-08 33.5 0.0 7.8 6 3 1 7 7 7 6 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) PNP_UDP_1 PF01048.15 KEP61263.1 - 2.7e-24 85.4 0.1 9.9e-24 83.5 0.1 2.0 1 0 0 1 1 1 1 Phosphorylase superfamily DHquinase_I PF01487.10 KEP61263.1 - 2.4e-14 53.5 0.0 1.5e-07 31.2 0.0 3.4 3 0 0 3 3 3 2 Type I 3-dehydroquinase SKI PF01202.17 KEP61263.1 - 1.6e-11 44.3 3.9 2.9e-05 23.9 0.0 4.5 4 1 1 5 5 5 2 Shikimate kinase Shikimate_dh_N PF08501.6 KEP61263.1 - 2.4e-10 40.3 0.0 4.7e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 KEP61263.1 - 7.1e-05 22.2 2.7 0.00022 20.6 0.2 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KEP61263.1 - 0.022 15.5 0.0 0.051 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain JmjC PF02373.17 KEP61265.1 - 1e-34 119.1 0.2 1.9e-34 118.2 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 KEP61265.1 - 0.009 15.5 0.0 0.009 15.5 0.0 1.7 2 0 0 2 2 2 1 jmjN domain Spore_coat_CotO PF14153.1 KEP61267.1 - 0.21 10.9 4.9 0.25 10.7 3.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4175 PF13779.1 KEP61267.1 - 4.4 4.8 10.7 4.9 4.7 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Cgr1 PF03879.9 KEP61267.1 - 5.4 7.2 22.7 10 6.3 15.6 1.6 1 1 0 1 1 1 0 Cgr1 family Thymidylate_kin PF02223.12 KEP61269.1 - 8.8e-31 106.7 0.0 6.3e-23 81.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.1 KEP61269.1 - 0.016 15.1 0.3 0.068 13.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEP61269.1 - 0.028 14.2 0.0 0.091 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain B3_4 PF03483.12 KEP61270.1 - 3.3e-22 78.7 0.0 6.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KEP61270.1 - 4e-16 58.5 0.0 8.1e-13 47.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain RAP PF08373.5 KEP61271.1 - 1e-16 60.4 0.0 1.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RAP domain Proteasome PF00227.21 KEP61272.1 - 8.4e-46 155.6 0.3 1e-45 155.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KEP61272.1 - 0.0084 15.3 0.1 0.022 14.0 0.0 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Proteasom_PSMB PF10508.4 KEP61274.1 - 8.6e-35 119.9 0.0 1.3e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 KEP61274.1 - 0.027 14.7 5.3 0.12 12.6 0.1 4.0 3 1 0 4 4 4 0 HEAT repeats Nol1_Nop2_Fmu PF01189.12 KEP61275.1 - 1.1e-32 113.5 0.0 1.9e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KEP61275.1 - 5.8e-07 29.5 0.0 2.1e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP61275.1 - 1.8e-06 28.5 0.0 3.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PUA PF01472.15 KEP61275.1 - 5.4e-06 26.0 0.0 1.4e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.14 KEP61275.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.14 KEP61275.1 - 0.00025 20.6 0.0 0.00062 19.3 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KEP61275.1 - 0.0032 17.0 0.0 0.047 13.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 KEP61275.1 - 0.098 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin SID-1_RNA_chan PF13965.1 KEP61276.1 - 0.077 11.1 3.5 0.11 10.5 2.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DC_STAMP PF07782.8 KEP61276.1 - 0.093 12.3 0.3 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 DC-STAMP-like protein Lon_C PF05362.8 KEP61278.1 - 1.7e-68 229.9 0.4 1.1e-57 194.6 0.0 2.8 3 0 0 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KEP61278.1 - 4.2e-21 75.5 0.0 1.2e-20 74.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KEP61278.1 - 8.3e-18 64.8 0.4 4.3e-17 62.4 0.0 2.4 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KEP61278.1 - 2.9e-08 33.5 0.0 2e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KEP61278.1 - 8.1e-08 31.8 0.0 1.6e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 KEP61278.1 - 8.2e-06 25.8 0.0 2.9e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEP61278.1 - 1.7e-05 24.9 3.4 3.1e-05 24.1 0.0 2.9 3 1 0 3 3 1 1 AAA domain AAA_PrkA PF08298.6 KEP61278.1 - 3.8e-05 22.5 0.0 6.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KEP61278.1 - 4.5e-05 24.2 0.0 0.00024 21.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEP61278.1 - 7.7e-05 23.0 1.1 0.0048 17.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEP61278.1 - 0.00015 21.7 0.1 0.001 19.1 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KEP61278.1 - 0.0012 17.9 0.0 0.0033 16.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KEP61278.1 - 0.0062 15.9 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KEP61278.1 - 0.0088 15.9 0.0 0.031 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KEP61278.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KEP61278.1 - 0.021 13.5 0.3 0.099 11.3 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus ATP-synt_ab PF00006.20 KEP61278.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KEP61278.1 - 0.03 13.7 0.0 0.085 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 KEP61278.1 - 0.03 14.1 4.5 0.2 11.4 0.0 3.4 4 0 0 4 4 3 0 Shikimate kinase DUF258 PF03193.11 KEP61278.1 - 0.032 13.4 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEP61278.1 - 0.045 13.6 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KEP61278.1 - 0.069 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KEP61278.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KEP61278.1 - 0.082 12.3 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 KEP61278.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain CaMBD PF02888.11 KEP61278.1 - 0.11 12.3 1.2 0.31 10.8 0.8 1.7 1 0 0 1 1 1 0 Calmodulin binding domain JAB PF01398.16 KEP61279.1 - 2.1e-24 85.4 0.0 3.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KEP61279.1 - 7.3e-07 28.7 0.2 3.3e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 KEP61279.1 - 0.057 12.9 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Ank_2 PF12796.2 KEP61280.1 - 2.5e-46 155.9 12.5 9.1e-16 57.9 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEP61280.1 - 1.5e-31 107.6 5.8 5.3e-11 42.3 0.1 5.7 3 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KEP61280.1 - 4.3e-30 102.0 9.1 4.6e-06 26.1 0.0 7.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.1 KEP61280.1 - 1.1e-26 92.7 4.2 2e-06 28.1 0.0 6.2 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP61280.1 - 3.7e-21 73.0 6.3 0.00031 20.7 0.1 7.6 7 1 0 7 7 7 5 Ankyrin repeat Sushi PF00084.15 KEP61280.1 - 1.1e-05 25.6 0.1 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Sushi domain (SCR repeat) DSPc PF00782.15 KEP61281.1 - 3.8e-30 104.1 0.0 4.4e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KEP61281.1 - 0.00015 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 KEP61281.1 - 0.0028 16.6 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 KEP61281.1 - 0.0028 17.0 0.3 0.0049 16.2 0.1 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KEP61281.1 - 0.047 13.1 0.2 1 8.8 0.1 2.1 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SAG PF04092.8 KEP61282.1 - 9.6e-15 55.0 0.8 1.1e-14 54.8 0.5 1.1 1 0 0 1 1 1 1 SRS domain AAA_25 PF13481.1 KEP61283.1 - 0.0001 21.7 0.0 0.00027 20.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEP61283.1 - 0.00029 20.5 0.1 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KEP61283.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain zf-CCCH_2 PF14608.1 KEP61285.1 - 5.2e-09 35.7 30.5 0.00024 20.9 3.6 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type PWI PF01480.12 KEP61285.1 - 0.054 13.6 0.1 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 PWI domain zf-CCCH PF00642.19 KEP61285.1 - 0.15 11.7 9.7 0.18 11.5 0.4 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHH PF10283.4 KEP61285.1 - 0.74 9.6 11.1 1 9.2 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif MIP-T3 PF10243.4 KEP61285.1 - 3.1 6.1 19.2 4.5 5.6 13.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IMS PF00817.15 KEP61286.1 - 8.8e-26 90.4 1.9 1.1e-17 64.2 0.0 3.1 2 1 0 2 2 2 2 impB/mucB/samB family HHH_5 PF14520.1 KEP61286.1 - 0.00016 21.7 0.2 0.00042 20.4 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.3 KEP61286.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif HHH_7 PF14635.1 KEP61287.1 - 1.3e-12 47.7 0.0 1.4e-10 41.2 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.1 KEP61287.1 - 1.5e-06 28.1 0.2 4.8e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2_2 PF14633.1 KEP61287.1 - 0.0069 15.4 0.0 1.9 7.4 0.0 2.9 2 0 0 2 2 2 2 SH2 domain YqgF PF14639.1 KEP61287.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Glyco_transf_8C PF08437.5 KEP61287.1 - 0.072 13.1 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal Mem_trans PF03547.13 KEP61287.1 - 9.1 4.4 2.2 67 1.6 0.7 2.1 2 0 0 2 2 2 0 Membrane transport protein RRM_6 PF14259.1 KEP61288.1 - 1.5e-21 76.1 0.0 1.5e-09 37.6 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP61288.1 - 1.6e-17 62.8 0.0 8.6e-06 25.3 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP61288.1 - 1.6e-13 50.2 0.1 0.0012 18.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KEP61288.1 - 1.1e-05 25.2 52.1 1.1e-05 25.2 36.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) Ribosomal_L33 PF00471.15 KEP61289.1 - 1.1e-10 41.5 0.7 4.5e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L33 CcoS PF03597.10 KEP61291.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type His_Phos_2 PF00328.17 KEP61292.1 - 0.021 14.1 0.0 0.38 10.0 0.0 2.5 3 0 0 3 3 3 0 Histidine phosphatase superfamily (branch 2) AAA PF00004.24 KEP61293.1 - 8.7e-45 152.1 0.0 1.3e-40 138.6 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP61293.1 - 2.2e-05 24.5 7.6 0.023 14.6 0.1 4.5 3 2 1 4 4 4 2 AAA ATPase domain IstB_IS21 PF01695.12 KEP61293.1 - 8.8e-05 21.9 0.0 0.0091 15.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 KEP61293.1 - 0.00011 22.3 1.4 0.14 12.3 0.0 4.0 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEP61293.1 - 0.00022 22.0 0.2 0.04 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEP61293.1 - 0.00028 20.6 1.6 0.0099 15.6 0.1 3.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEP61293.1 - 0.0005 19.7 0.3 0.049 13.3 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KEP61293.1 - 0.0012 18.7 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KEP61293.1 - 0.0018 17.9 1.2 2.6 7.6 0.0 3.9 2 2 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KEP61293.1 - 0.0018 18.1 0.1 0.088 12.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KEP61293.1 - 0.0026 17.1 0.5 4.4 6.6 0.0 3.4 4 0 0 4 4 4 2 AAA domain Mg_chelatase PF01078.16 KEP61293.1 - 0.013 14.7 0.2 0.058 12.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KEP61293.1 - 0.019 14.8 0.0 0.068 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 KEP61293.1 - 0.023 15.0 0.1 0.89 9.8 0.0 2.9 2 0 0 2 2 2 0 ABC transporter RuvB_N PF05496.7 KEP61293.1 - 0.053 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KEP61293.1 - 0.087 13.0 0.0 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 KEP61293.1 - 0.13 11.6 0.3 3.5 6.9 0.0 2.8 3 1 0 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 KEP61293.1 - 0.15 11.7 0.2 4.7 6.8 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase TIP49 PF06068.8 KEP61293.1 - 0.22 10.1 0.1 0.48 9.0 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus CBF_beta PF02312.12 KEP61295.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit POX PF07526.6 KEP61297.1 - 0.27 11.4 0.1 0.45 10.7 0.0 1.2 1 0 0 1 1 1 0 Associated with HOX EFP_N PF08207.7 KEP61299.1 - 0.00048 19.9 0.1 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 KEP61299.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain ATP_bind_3 PF01171.15 KEP61300.1 - 3.5e-17 62.4 0.0 1.6e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 PP-loop family tRNA_Me_trans PF03054.11 KEP61300.1 - 0.0012 17.4 0.0 0.0034 15.9 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.14 KEP61300.1 - 0.0015 18.3 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family RecR PF02132.10 KEP61300.1 - 0.014 14.8 0.5 0.014 14.8 0.3 3.3 4 0 0 4 4 4 0 RecR protein SLBP_RNA_bind PF15247.1 KEP61304.1 - 2.8e-23 81.4 0.5 5.9e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Adaptin_binding PF10199.4 KEP61305.1 - 4.4e-13 49.6 4.7 4.4e-13 49.6 3.2 2.9 3 1 0 3 3 3 1 Alpha and gamma adaptin binding protein p34 UCH PF00443.24 KEP61306.1 - 3e-30 105.2 0.0 3.9e-28 98.3 0.0 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP61306.1 - 2.3e-08 33.8 1.3 3.8e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF1664 PF07889.7 KEP61309.1 - 0.92 9.3 5.0 0.33 10.7 0.8 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.1 KEP61309.1 - 0.99 8.5 19.8 0.23 10.6 6.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 KEP61309.1 - 6.2 7.2 19.0 0.62 10.4 1.6 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Myticin-prepro PF10690.4 KEP61310.1 - 0.0034 17.3 0.2 0.005 16.8 0.2 1.2 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel Peroxin-3 PF04882.7 KEP61311.1 - 3.2e-07 29.4 0.0 1e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Peroxin-3 TRAP_alpha PF03896.11 KEP61311.1 - 0.6 9.0 7.2 0.094 11.7 0.3 2.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit tRNA_Me_trans PF03054.11 KEP61313.1 - 7.5e-74 248.4 0.0 1.4e-35 122.5 0.0 4.3 4 1 0 4 4 4 3 tRNA methyl transferase ThiI PF02568.9 KEP61313.1 - 0.0014 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Ribosomal_L4 PF00573.17 KEP61314.1 - 2.9e-41 140.9 0.1 6e-41 139.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KEP61314.1 - 7.5e-23 80.2 2.5 7.5e-23 80.2 1.8 2.1 1 1 1 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF3774 PF12609.3 KEP61314.1 - 3.7 8.4 8.4 5.5 7.9 1.3 2.8 1 1 1 2 2 2 0 Wound-induced protein WD40 PF00400.27 KEP61315.1 - 7e-20 70.1 13.2 8.8e-05 22.2 1.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat LisH PF08513.6 KEP61315.1 - 2.1e-07 30.4 0.3 4.2e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 KEP61315.1 - 0.072 11.2 0.1 0.28 9.2 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 HSD3 PF15244.1 KEP61316.1 - 0.021 14.0 4.6 0.03 13.5 3.2 1.1 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase TP53IP5 PF15331.1 KEP61316.1 - 0.03 14.2 7.1 0.05 13.5 4.9 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 ATG16 PF08614.6 KEP61316.1 - 0.048 13.4 7.9 0.77 9.5 0.4 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Med28 PF11594.3 KEP61316.1 - 0.13 12.4 1.1 0.25 11.5 0.8 1.5 1 0 0 1 1 1 0 Mediator complex subunit 28 Spectrin PF00435.16 KEP61316.1 - 0.64 10.3 8.6 0.059 13.6 1.4 2.4 2 1 1 3 3 3 0 Spectrin repeat Pax2_C PF12403.3 KEP61317.1 - 0.025 14.2 0.1 0.042 13.5 0.0 1.4 1 1 0 1 1 1 0 Paired-box protein 2 C terminal CPSase_L_D2 PF02786.12 KEP61320.1 - 1.4e-71 240.1 0.4 2.6e-71 239.2 0.3 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KEP61320.1 - 1.2e-62 210.8 0.0 2e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KEP61320.1 - 5.9e-36 122.9 0.1 1.7e-35 121.4 0.0 1.9 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEP61320.1 - 6.1e-35 119.4 0.0 3.3e-33 113.8 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KEP61320.1 - 8.2e-29 100.9 0.0 1.5e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 KEP61320.1 - 7.9e-19 67.0 1.3 1.8e-18 65.9 0.9 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KEP61320.1 - 3.7e-18 65.9 0.7 9.6e-18 64.5 0.5 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEP61320.1 - 8.7e-15 54.2 0.1 3.6e-14 52.2 0.0 1.9 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KEP61320.1 - 3.4e-12 45.8 2.1 2.1e-05 24.0 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KEP61320.1 - 2.1e-08 33.7 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEP61320.1 - 5.4e-07 29.1 0.1 1.2e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 KEP61320.1 - 1e-05 25.0 1.6 0.0012 18.2 0.2 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 KEP61320.1 - 3.4e-05 23.1 0.2 0.11 11.6 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 KEP61320.1 - 0.00025 21.3 0.9 0.78 10.1 0.1 2.8 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.6 KEP61320.1 - 0.047 13.1 0.1 3.5 7.0 0.0 2.7 3 0 0 3 3 3 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KEP61320.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_YheCD PF14398.1 KEP61320.1 - 0.51 9.0 0.0 0.83 8.3 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp zf-DHHC PF01529.15 KEP61322.1 - 4.6e-30 104.2 18.2 4.7e-27 94.4 6.0 3.6 4 0 0 4 4 4 2 DHHC palmitoyltransferase SET PF00856.23 KEP61323.1 - 2e-06 28.2 0.0 0.0019 18.5 0.0 3.0 2 1 0 2 2 2 1 SET domain Mito_fiss_reg PF05308.6 KEP61323.1 - 0.39 10.0 12.3 0.63 9.3 8.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator HA2 PF04408.18 KEP61324.1 - 1.4e-13 50.7 0.0 6e-13 48.6 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEP61324.1 - 1.8e-13 50.1 0.0 5.1e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KEP61324.1 - 2e-12 46.9 0.0 6.3e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KEP61324.1 - 3.4e-07 29.9 0.0 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEP61324.1 - 7.4e-05 22.9 0.0 0.00048 20.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KEP61324.1 - 0.0042 16.0 0.2 0.0098 14.8 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein DND1_DSRM PF14709.1 KEP61324.1 - 0.016 15.5 0.4 0.1 12.9 0.2 2.4 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 KEP61324.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RRM_1 PF00076.17 KEP61325.1 - 8e-14 51.0 0.0 1.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP61325.1 - 1.1e-12 47.7 0.0 2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP61325.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5_3_exonuc_N PF02739.11 KEP61329.1 - 3.4e-36 124.1 0.0 5.5e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 KEP61329.1 - 4.7e-09 36.3 0.0 9.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 KEP61329.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain NYN_YacP PF05991.6 KEP61329.1 - 0.48 10.1 5.5 0.23 11.1 0.2 2.7 2 1 1 3 3 3 0 YacP-like NYN domain AAA PF00004.24 KEP61330.1 - 1.7e-12 47.6 0.0 3.6e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP61330.1 - 6.2e-08 32.8 0.1 2.2e-07 31.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEP61330.1 - 1.9e-07 31.2 0.0 7.6e-06 26.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEP61330.1 - 0.01 15.4 0.2 0.91 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEP61330.1 - 0.012 15.3 0.1 0.039 13.7 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 KEP61330.1 - 0.067 11.9 0.1 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF4192 PF13830.1 KEP61330.1 - 0.098 12.2 7.0 0.13 11.9 3.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) UPF0079 PF02367.12 KEP61330.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Cupin_8 PF13621.1 KEP61331.1 - 1.7e-19 70.3 0.0 1.6e-18 67.0 0.0 2.4 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 KEP61331.1 - 5e-11 42.8 0.1 4.6e-10 39.7 0.1 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KEP61331.1 - 0.044 13.2 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.7 KEP61331.1 - 0.051 12.8 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Na_trans_assoc PF06512.8 KEP61331.1 - 0.11 12.5 2.2 0.19 11.7 1.5 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated CAP_N PF01213.14 KEP61331.1 - 0.8 8.9 5.6 0.32 10.2 0.7 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Keratin_matx PF04579.7 KEP61332.1 - 0.037 14.2 3.7 0.086 13.1 0.7 2.2 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein RRM_1 PF00076.17 KEP61333.1 - 3.4e-18 65.0 0.2 2.7e-17 62.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP61333.1 - 4.5e-14 52.1 0.0 4.8e-12 45.6 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP61333.1 - 1.5e-07 31.1 0.0 3.8e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surf_Ag_VNR PF07244.10 KEP61333.1 - 0.066 13.6 0.0 7.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Surface antigen variable number repeat LRR_4 PF12799.2 KEP61334.1 - 1.3e-12 46.9 9.6 6.6e-05 22.4 0.3 4.3 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEP61334.1 - 3.7e-06 26.2 9.5 1.7 8.9 0.0 5.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.1 KEP61334.1 - 1.2e-05 24.9 11.3 0.0064 16.2 0.8 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_7 PF13504.1 KEP61334.1 - 0.00018 21.1 6.9 31 5.3 0.3 6.2 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 KEP61334.1 - 0.0023 17.7 3.7 16 5.9 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.1 KEP61334.1 - 0.051 13.1 3.4 0.13 11.8 1.6 1.9 1 1 1 2 2 2 0 Leucine-rich repeat Pro_isomerase PF00160.16 KEP61335.1 - 5.2e-46 156.6 0.4 1e-45 155.7 0.3 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.23 KEP61335.1 - 9.8e-31 105.6 0.0 2.3e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 KEP61335.1 - 7.4e-19 67.1 0.7 1.1e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEP61335.1 - 9.3e-16 56.6 1.3 4.7e-05 22.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP61335.1 - 1.1e-12 46.8 2.9 0.0015 18.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEP61335.1 - 1.4e-07 31.9 1.4 0.00036 21.1 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP61335.1 - 2.1e-05 24.3 1.4 0.0014 18.4 0.3 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP61335.1 - 4.7e-05 23.6 0.3 0.012 16.1 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP61335.1 - 0.00066 19.2 0.2 0.011 15.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP61335.1 - 0.00067 19.2 0.1 1.7 8.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP61335.1 - 0.0019 18.2 0.0 0.067 13.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP61335.1 - 0.02 15.2 0.2 0.24 11.7 0.0 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEP61335.1 - 0.13 12.1 0.1 0.82 9.5 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 KEP61335.1 - 0.19 12.0 1.9 0.34 11.2 1.3 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain MIT PF04212.13 KEP61335.1 - 0.3 11.0 1.9 4 7.3 0.0 2.5 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain GATA PF00320.22 KEP61336.1 - 1.2e-05 24.5 4.1 4.1e-05 22.8 2.9 2.0 1 0 0 1 1 1 1 GATA zinc finger Pyrophosphatase PF00719.14 KEP61337.1 - 8e-47 158.5 0.0 1.1e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase GCV_T PF01571.16 KEP61338.1 - 5.8e-22 78.0 0.0 8.7e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KEP61338.1 - 5.4e-08 32.7 0.0 1.2e-06 28.4 0.0 2.9 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Raffinose_syn PF05691.7 KEP61339.1 - 1.1e-34 119.0 0.4 5e-16 57.4 0.1 3.1 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Pkinase PF00069.20 KEP61340.1 - 1.7e-33 115.9 0.0 8.5e-33 113.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61340.1 - 4.4e-14 52.1 0.0 1.6e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP61340.1 - 0.049 12.5 0.0 0.59 9.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like PGI PF00342.14 KEP61341.1 - 4.7e-188 625.5 0.0 5.5e-188 625.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase B9-C2 PF07162.6 KEP61342.1 - 5.2e-32 110.9 0.0 8.5e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SIR2 PF02146.12 KEP61343.1 - 2.7e-07 30.5 0.3 0.03 14.0 0.0 3.9 4 0 0 4 4 4 3 Sir2 family RRM_1 PF00076.17 KEP61344.1 - 2e-16 59.3 0.0 3.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP61344.1 - 2.2e-12 46.7 0.0 4.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 KEP61344.1 - 4.2e-11 42.7 0.0 9.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 KEP61344.1 - 1.2e-08 34.6 0.0 1.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) peroxidase PF00141.18 KEP61344.1 - 0.041 13.3 0.1 0.091 12.2 0.0 1.5 2 0 0 2 2 2 0 Peroxidase EMP70 PF02990.11 KEP61345.1 - 2.9e-133 445.1 1.8 2.9e-133 445.1 1.3 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 PTPA PF03095.10 KEP61346.1 - 6.7e-95 317.7 0.0 2e-78 263.5 0.0 2.6 2 1 0 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein TRAM_LAG1_CLN8 PF03798.11 KEP61347.1 - 2.3e-28 99.0 16.5 3.8e-28 98.4 11.4 1.3 1 0 0 1 1 1 1 TLC domain NADH-u_ox-rdase PF10785.4 KEP61347.1 - 0.16 12.2 1.9 0.29 11.4 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PI3_PI4_kinase PF00454.22 KEP61348.1 - 4.3e-34 118.0 0.0 6.7e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KEP61348.1 - 7.8e-09 34.8 0.1 1.9e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain PrsW-protease PF13367.1 KEP61348.1 - 0.8 8.8 0.2 1.5 7.9 0.1 1.4 1 0 0 1 1 1 0 Protease prsW family zf-CpG_bind_C PF12269.3 KEP61348.1 - 6.3 6.2 0.0 13 5.1 0.0 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain NIF PF03031.13 KEP61349.1 - 3.5e-16 59.2 0.0 5.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DnaJ PF00226.26 KEP61350.1 - 1e-14 54.0 0.5 2.5e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 DnaJ domain Ras PF00071.17 KEP61353.1 - 4.8e-47 159.3 0.6 5.6e-47 159.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP61353.1 - 2.1e-18 66.9 0.1 3.6e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP61353.1 - 1.3e-09 37.5 0.1 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEP61353.1 - 2.7e-07 30.5 0.1 4.6e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP61353.1 - 3.8e-07 29.7 0.5 1.7e-06 27.6 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEP61353.1 - 0.00012 21.4 0.1 0.069 12.4 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B PduV-EutP PF10662.4 KEP61353.1 - 0.00018 21.0 0.4 0.099 12.1 0.1 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 KEP61353.1 - 0.013 14.6 0.1 0.025 13.6 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KEP61353.1 - 0.086 12.0 0.1 0.21 10.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF1542 PF07564.6 KEP61355.1 - 0.29 11.1 1.1 0.59 10.1 0.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) TPR_19 PF14559.1 KEP61356.1 - 3.5e-19 68.9 7.2 4.8e-06 26.8 0.1 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEP61356.1 - 1.6e-14 53.2 18.1 3e-05 23.5 0.1 6.0 4 2 4 8 8 7 4 TPR repeat Apc3 PF12895.2 KEP61356.1 - 2.5e-11 43.5 12.2 0.0044 17.1 0.0 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KEP61356.1 - 6.7e-11 42.5 10.8 0.012 16.2 0.0 6.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP61356.1 - 1.6e-07 30.7 13.8 0.26 11.3 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP61356.1 - 2.3e-07 30.6 17.4 0.00026 20.8 0.9 6.3 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEP61356.1 - 5.7e-07 29.6 9.4 0.99 10.2 0.0 7.7 4 2 4 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEP61356.1 - 4.2e-05 23.0 3.5 0.0037 16.9 0.1 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEP61356.1 - 0.00032 20.1 16.0 0.084 12.5 0.2 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEP61356.1 - 0.002 18.4 13.6 0.5 10.9 0.1 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEP61356.1 - 0.069 13.0 5.3 0.57 10.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 KEP61356.1 - 0.08 12.7 2.0 4.9 7.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Type_III_YscG PF09477.5 KEP61356.1 - 0.79 9.8 7.1 3 7.9 0.2 3.3 3 0 0 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_21 PF09976.4 KEP61356.1 - 1.7 8.5 6.4 5.7 6.8 1.8 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF1640 PF07798.6 KEP61357.1 - 0.00092 19.2 0.9 0.001 19.1 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CENP-F_leu_zip PF10473.4 KEP61357.1 - 0.028 14.2 3.8 0.028 14.2 2.6 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2491 PF10679.4 KEP61357.1 - 0.053 12.5 0.1 0.058 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) MaoC_dehydrat_N PF13452.1 KEP61357.1 - 0.087 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Alpha-amylase PF00128.19 KEP61358.1 - 6.1e-31 107.9 0.0 9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amyl_C2 PF07821.7 KEP61358.1 - 3.8e-16 58.7 0.1 7e-16 57.8 0.1 1.5 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain fn3 PF00041.16 KEP61358.1 - 3.5e-05 23.8 0.1 0.00025 21.1 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain Pkinase PF00069.20 KEP61359.1 - 2.2e-52 177.7 0.0 2.9e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61359.1 - 2.1e-17 63.0 0.0 4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP61359.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP61359.1 - 0.052 12.5 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KEP61359.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kazal_2 PF07648.10 KEP61360.1 - 0.00015 21.5 2.9 0.00015 21.5 2.0 2.1 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 KEP61360.1 - 0.0018 18.2 4.9 0.003 17.5 3.4 1.6 1 1 0 1 1 1 1 Kazal-type serine protease inhibitor domain SAG PF04092.8 KEP61361.1 - 4.2e-05 23.9 0.0 7.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 SRS domain DUF4463 PF14703.1 KEP61364.1 - 0.019 15.4 5.3 0.41 11.2 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Vps35 PF03635.12 KEP61364.1 - 0.096 10.8 3.6 0.15 10.1 0.1 2.0 1 1 1 2 2 2 0 Vacuolar protein sorting-associated protein 35 FlgN PF05130.7 KEP61364.1 - 0.15 12.3 12.1 0.58 10.4 6.3 2.1 1 1 1 2 2 2 0 FlgN protein 5_3_exonuc PF01367.15 KEP61364.1 - 0.2 11.8 5.0 1.1 9.5 3.4 2.1 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold CDC37_N PF03234.9 KEP61364.1 - 0.21 11.9 7.4 1 9.6 5.1 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding APG6 PF04111.7 KEP61364.1 - 0.28 10.1 6.7 0.46 9.4 4.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KEP61364.1 - 0.57 9.0 6.4 0.86 8.4 4.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL6 PF01763.11 KEP61364.1 - 1.7 6.6 6.8 2.3 6.2 4.5 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like GDI PF00996.13 KEP61365.1 - 2.1e-25 88.9 0.0 2.2e-07 29.6 0.0 4.1 4 0 0 4 4 4 4 GDP dissociation inhibitor FAD_binding_2 PF00890.19 KEP61365.1 - 7e-05 21.8 0.1 0.00011 21.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KEP61365.1 - 9.8e-05 21.5 0.9 0.00016 20.8 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEP61365.1 - 0.00024 21.0 0.4 0.00061 19.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEP61365.1 - 0.0039 16.1 0.3 0.0095 14.8 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEP61365.1 - 0.0076 15.3 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KEP61365.1 - 0.012 15.9 0.2 0.028 14.8 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEP61365.1 - 0.036 12.9 0.2 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Myosin_N PF02736.14 KEP61365.1 - 0.11 12.1 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain GIDA PF01134.17 KEP61365.1 - 0.13 11.0 0.3 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Abhydrolase_1 PF00561.15 KEP61367.1 - 1.1e-19 70.9 0.1 2.8e-18 66.3 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEP61367.1 - 4.6e-15 56.1 0.1 8.8e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KEP61367.1 - 6.9e-06 25.6 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KEP61367.1 - 0.00093 18.9 0.1 0.0077 16.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEP61367.1 - 0.029 13.6 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family AP2 PF00847.15 KEP61371.1 - 2.7e-13 49.8 1.7 6.6e-13 48.5 1.2 1.7 1 0 0 1 1 1 1 AP2 domain SNAP PF14938.1 KEP61372.1 - 4.2e-13 49.0 11.7 6.4e-13 48.4 8.1 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KEP61372.1 - 0.0066 16.3 4.5 0.51 10.3 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1342 PF07072.6 KEP61372.1 - 0.019 14.6 1.5 0.023 14.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) DNA_primase_S PF01896.14 KEP61372.1 - 0.14 11.9 0.2 0.29 10.9 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit CHCH PF06747.8 KEP61372.1 - 1.1 9.2 5.3 3.3 7.7 0.0 3.2 2 1 1 3 3 3 0 CHCH domain Vps16_N PF04841.8 KEP61375.1 - 3.6e-58 197.0 0.0 2.2e-57 194.4 0.0 2.0 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KEP61375.1 - 8.3e-52 176.1 0.1 1.3e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Ank_2 PF12796.2 KEP61377.1 - 1.1e-08 35.3 0.1 0.0026 18.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEP61377.1 - 1.7e-08 33.8 3.4 0.0044 16.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KEP61377.1 - 5.2e-08 32.8 1.8 0.00014 21.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEP61377.1 - 5.2e-08 33.1 0.7 0.011 16.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP61377.1 - 1.5e-05 24.7 1.0 0.094 13.0 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat Pro_isomerase PF00160.16 KEP61378.1 - 7e-53 178.9 0.5 1.7e-52 177.7 0.4 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KEP61378.1 - 4.4e-10 39.0 5.5 0.0074 16.1 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Choline_kinase PF01633.15 KEP61379.1 - 1.9e-39 135.4 0.0 3.6e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 KEP61379.1 - 2.5e-11 43.7 4.5 3.9e-10 39.8 2.4 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family TGT PF01702.13 KEP61380.1 - 2.9e-75 252.6 0.0 3.1e-61 206.6 0.0 2.2 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase SAC3_GANP PF03399.11 KEP61381.1 - 0.00036 20.1 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CSD PF00313.17 KEP61382.1 - 6.6e-23 80.2 1.1 1e-22 79.6 0.8 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KEP61382.1 - 0.00092 18.6 0.2 0.0023 17.3 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease B OB domain FAST_1 PF06743.10 KEP61383.1 - 0.0091 15.6 9.5 2.7 7.7 0.0 6.0 5 1 1 6 6 6 3 FAST kinase-like protein, subdomain 1 Glyco_hydro_35 PF01301.14 KEP61384.1 - 1.1e-20 74.3 0.0 1.7e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Shisa PF13908.1 KEP61384.1 - 0.19 11.8 0.2 0.57 10.3 0.2 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Streptin-Immun PF11083.3 KEP61385.1 - 0.0013 18.6 1.8 0.0013 18.6 1.2 2.6 2 1 1 3 3 3 1 Lantibiotic streptin immunity protein DUF4102 PF13356.1 KEP61385.1 - 0.05 13.4 1.3 0.21 11.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4102) DUF2486 PF10667.4 KEP61385.1 - 0.16 12.4 6.4 0.33 11.4 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) LTXXQ PF07813.7 KEP61385.1 - 0.55 10.7 7.7 4.7 7.7 0.1 2.6 2 0 0 2 2 2 0 LTXXQ motif family protein SPT16 PF08644.6 KEP61385.1 - 4.8 6.9 6.9 1.9 8.2 2.5 1.9 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) GTP_EFTU PF00009.22 KEP61386.1 - 2.7e-46 157.4 0.0 3.1e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEP61386.1 - 1.3e-20 73.3 0.2 8.1e-20 70.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEP61386.1 - 1.9e-07 31.0 0.2 7.1e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEP61386.1 - 0.00077 19.3 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.10 KEP61386.1 - 0.0065 15.9 2.1 0.0086 15.5 0.4 2.1 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Dioxygenase_N PF04444.9 KEP61386.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus G-alpha PF00503.15 KEP61386.1 - 0.16 10.6 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit p25-alpha PF05517.7 KEP61387.1 - 4.5e-42 143.8 1.0 5e-42 143.7 0.7 1.0 1 0 0 1 1 1 1 p25-alpha RCC1 PF00415.13 KEP61389.1 - 4.7 7.5 4.8 4.8 7.4 0.1 3.1 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KEP61390.1 - 2.6e-07 30.7 11.3 37 4.6 0.0 8.5 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat DUF1897 PF09005.5 KEP61390.1 - 0.19 11.2 9.9 21 4.6 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) DUF1308 PF07000.6 KEP61391.1 - 2.3e-16 59.3 0.0 2.8e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) MelC1 PF06236.6 KEP61391.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 Patched PF02460.13 KEP61393.1 - 8.8e-81 271.9 17.2 1.3e-37 129.2 0.0 3.1 2 1 1 3 3 3 3 Patched family Sterol-sensing PF12349.3 KEP61393.1 - 2.2e-32 111.6 21.8 1.1e-30 106.1 0.6 2.8 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 KEP61393.1 - 0.0013 16.2 20.7 0.0019 15.7 14.4 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.11 KEP61393.1 - 3.3 6.8 23.0 0.14 11.3 11.4 2.0 2 0 0 2 2 2 0 Protein export membrane protein Lactamase_B_2 PF12706.2 KEP61394.1 - 1.5e-30 106.2 0.4 2.2e-30 105.6 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEP61394.1 - 2.3e-10 40.4 0.0 4.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEP61394.1 - 0.035 13.7 6.5 0.45 10.1 4.5 2.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Ras PF00071.17 KEP61396.1 - 9.3e-50 168.1 0.0 1.2e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP61396.1 - 7.9e-18 65.0 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP61396.1 - 1.8e-11 43.5 0.0 2.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEP61396.1 - 2.3e-06 27.1 0.0 6.6e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEP61396.1 - 5.2e-06 25.7 0.0 6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEP61396.1 - 0.00015 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEP61396.1 - 0.11 11.6 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KEP61396.1 - 0.16 11.9 0.3 2.3 8.1 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain ABC_membrane PF00664.18 KEP61398.1 - 6.1e-60 202.9 12.4 9.4e-33 113.7 0.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEP61398.1 - 2.8e-46 157.2 0.0 7.2e-27 94.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEP61398.1 - 1.3e-06 27.7 0.0 0.86 8.7 0.0 3.6 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEP61398.1 - 4.4e-06 26.1 2.1 0.023 14.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KEP61398.1 - 5.2e-06 25.9 0.2 0.044 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KEP61398.1 - 0.00017 21.5 0.2 0.39 10.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 KEP61398.1 - 0.00027 20.9 0.3 2.1 8.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 KEP61398.1 - 0.0015 19.0 0.3 1.9 9.0 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 KEP61398.1 - 0.0016 17.4 0.3 0.26 10.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 KEP61398.1 - 0.0022 17.1 0.5 1 8.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEP61398.1 - 0.026 14.6 1.8 5.8 7.0 0.1 3.7 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 KEP61398.1 - 0.032 13.7 1.2 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 KEP61398.1 - 0.11 11.1 0.1 0.83 8.2 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_23 PF13476.1 KEP61398.1 - 0.12 12.6 2.1 11 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Pex14_N PF04695.8 KEP61398.1 - 0.15 12.1 3.3 0.14 12.1 0.8 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dynamin_N PF00350.18 KEP61398.1 - 0.16 11.8 1.7 3.8 7.2 0.2 2.3 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.10 KEP61398.1 - 0.16 11.7 0.2 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 NTPase AAA_10 PF12846.2 KEP61398.1 - 0.22 10.9 3.1 8 5.8 0.3 2.4 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 KEP61398.1 - 0.27 10.9 1.9 9.7 5.8 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KEP61398.1 - 0.39 10.1 3.6 5.3 6.4 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KEP61398.1 - 0.39 11.5 5.5 8.3 7.2 0.3 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KEP61398.1 - 0.47 10.2 6.6 4.7 6.9 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 KEP61398.1 - 0.71 8.9 1.6 13 4.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 KEP61398.1 - 3.8 7.8 3.8 32 4.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain RRS1 PF04939.7 KEP61399.1 - 2.7e-36 124.5 7.2 2.7e-36 124.5 5.0 2.8 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Sec5 PF15469.1 KEP61399.1 - 0.57 9.8 3.5 0.36 10.5 0.2 2.0 2 0 0 2 2 2 0 Exocyst complex component Sec5 XRN_N PF03159.13 KEP61400.1 - 2e-20 73.1 0.0 7.1e-07 28.8 0.0 4.3 4 0 0 4 4 4 4 XRN 5'-3' exonuclease N-terminus MIF4G PF02854.14 KEP61401.1 - 1.8e-24 86.3 0.1 1.8e-24 86.3 0.1 2.2 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 KEP61401.1 - 4.3e-15 55.3 1.3 9.2e-15 54.3 0.9 1.6 1 0 0 1 1 1 1 MA3 domain SNF2_N PF00176.18 KEP61402.1 - 3.4e-73 246.0 0.0 6.2e-73 245.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP61402.1 - 1.6e-14 53.5 0.1 4.3e-13 48.9 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KEP61402.1 - 1.5e-12 46.9 0.1 8.3e-12 44.5 0.1 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SnAC PF14619.1 KEP61402.1 - 6.2e-12 45.5 0.4 6.2e-12 45.5 0.3 5.8 8 0 0 8 8 8 1 Snf2-ATP coupling, chromatin remodelling complex DEAD PF00270.24 KEP61402.1 - 1.7e-05 24.3 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3246 PF11596.3 KEP61404.1 - 0.58 9.3 8.1 1.5 8.0 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Nucleoside_tran PF01733.13 KEP61405.1 - 0.0011 18.1 9.7 0.13 11.4 0.7 4.0 4 0 0 4 4 4 3 Nucleoside transporter U79_P34 PF03064.11 KEP61405.1 - 2 7.8 5.8 0.33 10.4 0.6 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Folate_rec PF03024.9 KEP61406.1 - 0.016 14.8 2.0 0.032 13.8 1.4 1.4 1 0 0 1 1 1 0 Folate receptor family SAG PF04092.8 KEP61407.1 - 6.4e-14 52.4 0.3 3.8e-10 40.2 0.2 2.0 2 0 0 2 2 2 2 SRS domain Amidase_5 PF05382.8 KEP61407.1 - 0.074 12.6 0.1 4.5 6.8 0.0 2.1 1 1 1 2 2 2 0 Bacteriophage peptidoglycan hydrolase SAG PF04092.8 KEP61408.1 - 1.9e-54 183.3 28.6 3e-33 114.8 8.0 2.2 2 0 0 2 2 2 2 SRS domain C2-set_2 PF08205.7 KEP61408.1 - 6.9 6.6 13.2 3.5 7.6 0.3 4.5 3 1 1 4 4 4 0 CD80-like C2-set immunoglobulin domain Rieske PF00355.21 KEP61409.1 - 2.8e-15 55.6 0.1 5.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 KEP61409.1 - 5.9e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region WD40 PF00400.27 KEP61410.1 - 1.7e-51 170.3 9.5 8.6e-12 44.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 KEP61410.1 - 2.4e-28 97.6 5.0 2.4e-28 97.6 3.5 2.3 2 0 0 2 2 2 1 Prp19/Pso4-like Nup160 PF11715.3 KEP61410.1 - 6.8e-06 24.4 0.1 0.02 13.0 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 zf-Nse PF11789.3 KEP61410.1 - 0.0044 16.5 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 KEP61410.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain Nbas_N PF15492.1 KEP61410.1 - 0.054 12.5 0.1 6.5 5.7 0.0 2.3 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal SYF2 PF08231.7 KEP61410.1 - 0.24 11.5 0.5 0.41 10.7 0.4 1.3 1 0 0 1 1 1 0 SYF2 splicing factor SAG PF04092.8 KEP61411.1 - 2.5e-52 176.4 23.6 1e-30 106.6 6.1 2.2 2 0 0 2 2 2 2 SRS domain DIX PF00778.12 KEP61414.1 - 0.00091 18.9 0.1 0.0072 16.0 0.0 2.0 1 1 0 1 1 1 1 DIX domain Pribosyltran_N PF13793.1 KEP61415.1 - 2.4e-47 159.4 0.3 1.1e-45 154.0 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEP61415.1 - 4.8e-32 111.1 0.1 1.1e-31 110.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEP61415.1 - 8.5e-12 44.8 0.1 6.6e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEP61415.1 - 0.0036 16.5 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Macoilin PF09726.4 KEP61416.1 - 0.89 7.7 9.3 1.6 6.9 6.5 1.3 1 0 0 1 1 1 0 Transmembrane protein AP-5_subunit_s1 PF15001.1 KEP61418.1 - 7.2e-29 101.0 0.0 5.4e-24 85.1 0.0 2.1 2 0 0 2 2 2 2 AP-5 complex subunit sigma-1 PPDFL PF15060.1 KEP61418.1 - 1.2 9.1 6.8 0.36 10.8 1.4 2.1 1 1 1 2 2 2 0 Differentiation and proliferation regulator EF-hand_7 PF13499.1 KEP61420.1 - 2e-22 79.1 0.3 2.6e-13 49.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP61420.1 - 1.7e-20 70.7 1.7 2.9e-07 29.3 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KEP61420.1 - 5e-20 69.5 0.7 2.2e-07 30.1 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KEP61420.1 - 6.1e-17 60.9 2.4 2.5e-08 33.4 0.0 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KEP61420.1 - 3.2e-13 48.3 3.3 3.2e-06 26.2 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 KEP61420.1 - 0.00011 22.0 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 KEP61420.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand SAP PF02037.22 KEP61420.1 - 0.2 11.2 0.6 0.39 10.2 0.2 1.7 2 0 0 2 2 2 0 SAP domain Ribosomal_L16 PF00252.13 KEP61421.1 - 3.2e-21 75.4 0.0 4.1e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e WD40 PF00400.27 KEP61422.1 - 1.5e-05 24.6 5.5 0.0073 16.1 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF2052 PF09747.4 KEP61423.1 - 2.5e-27 95.9 57.2 5.6e-16 58.9 12.2 4.1 2 1 1 3 3 3 2 Coiled-coil domain containing protein (DUF2052) Mem_trans PF03547.13 KEP61423.1 - 0.11 10.7 2.0 0.14 10.4 1.4 1.3 1 0 0 1 1 1 0 Membrane transport protein CAF-1_p150 PF11600.3 KEP61423.1 - 0.39 10.0 51.0 1.1 8.5 7.7 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAB3GAP2_C PF14656.1 KEP61423.1 - 3.6 5.6 6.5 6.4 4.7 4.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Bcr-Abl_Oligo PF09036.5 KEP61425.1 - 0.0087 15.9 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain SNARE PF05739.14 KEP61425.1 - 0.0094 15.6 1.5 0.023 14.3 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Serine_rich PF08824.5 KEP61425.1 - 0.09 12.4 5.9 0.52 10.0 1.8 2.4 2 0 0 2 2 2 0 Serine rich protein interaction domain Synaptobrevin PF00957.16 KEP61425.1 - 0.15 11.7 0.1 0.4 10.3 0.1 1.8 1 1 0 1 1 1 0 Synaptobrevin TMV_coat PF00721.16 KEP61425.1 - 1.9 8.3 4.9 0.51 10.2 0.5 2.1 2 0 0 2 2 2 0 Virus coat protein (TMV like) SOBP PF15279.1 KEP61425.1 - 7.1 6.9 13.7 4.4 7.6 6.2 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein PseudoU_synth_1 PF01416.15 KEP61428.1 - 1e-32 112.6 0.1 1.3e-16 60.9 0.0 3.0 3 0 0 3 3 3 2 tRNA pseudouridine synthase SOBP PF15279.1 KEP61428.1 - 0.013 15.8 4.1 0.013 15.8 2.9 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Herpes_DNAp_acc PF04929.7 KEP61428.1 - 5 5.9 20.3 4.6 6.1 6.8 2.3 2 0 0 2 2 2 0 Herpes DNA replication accessory factor AUX_IAA PF02309.11 KEP61428.1 - 8.4 6.0 14.7 0.76 9.4 2.5 2.2 2 0 0 2 2 2 0 AUX/IAA family LRR_6 PF13516.1 KEP61429.1 - 6.1e-11 41.2 5.4 0.16 12.1 0.0 8.3 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.2 KEP61429.1 - 1.6e-10 40.3 5.1 0.00013 21.5 0.0 6.4 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEP61429.1 - 9.8e-08 31.0 10.6 0.82 9.9 0.2 8.5 9 1 1 10 10 10 2 Leucine Rich Repeat LRR_7 PF13504.1 KEP61429.1 - 8.8e-06 25.1 12.4 0.72 10.3 0.0 8.2 9 0 0 9 9 9 1 Leucine rich repeat LRR_8 PF13855.1 KEP61429.1 - 0.0005 19.7 11.1 0.0061 16.2 0.1 5.8 6 1 0 6 6 6 1 Leucine rich repeat Voldacs PF03517.8 KEP61431.1 - 1.7e-34 118.5 0.0 2.6e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF2819 PF10995.3 KEP61431.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) Pneumo_att_G PF05539.6 KEP61432.1 - 0.8 9.0 2.3 0.61 9.3 0.1 1.7 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G IMCp PF12314.3 KEP61433.1 - 0.0028 17.7 52.3 0.014 15.5 16.7 4.3 1 1 3 4 4 4 2 Inner membrane complex protein Neogenin_C PF06583.7 KEP61433.1 - 0.37 10.2 3.1 0.71 9.3 2.1 1.5 1 0 0 1 1 1 0 Neogenin C-terminus CAP PF00188.21 KEP61434.1 - 9.2e-15 55.2 8.5 3.1e-11 43.8 2.7 2.4 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Mucin PF01456.12 KEP61434.1 - 9.7e-07 28.6 33.3 9.7e-07 28.6 23.1 2.0 2 1 0 2 2 2 1 Mucin-like glycoprotein Dicty_REP PF05086.7 KEP61434.1 - 2.2 5.9 14.3 3.8 5.1 9.9 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PapD-like PF14874.1 KEP61435.1 - 2.9e-10 40.0 0.1 4.6e-05 23.3 0.0 5.0 4 1 1 5 5 5 2 Flagellar-associated PapD-like Ribosomal_L18e PF00828.14 KEP61436.1 - 1.4e-10 41.6 3.7 2.8e-09 37.4 0.7 3.4 2 1 0 2 2 2 1 Ribosomal protein L18e/L15 BSD PF03909.12 KEP61437.1 - 1.9e-14 53.1 0.0 3.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 BSD domain Solute_trans_a PF03619.11 KEP61439.1 - 7.3e-15 55.0 2.0 1.3e-09 37.8 1.4 2.2 2 0 0 2 2 2 2 Organic solute transporter Ostalpha DUF4131 PF13567.1 KEP61439.1 - 0.00025 20.4 7.0 0.021 14.2 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) PMP1_2 PF08114.6 KEP61439.1 - 0.05 13.0 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 ATPase proteolipid family DUF3953 PF13129.1 KEP61439.1 - 2.3 7.8 7.6 0.28 10.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) Solute_trans_a PF03619.11 KEP61440.1 - 8.5e-22 77.7 4.8 2.1e-19 69.9 1.9 2.3 2 0 0 2 2 2 2 Organic solute transporter Ostalpha tRNA-synt_2 PF00152.15 KEP61441.1 - 3.6e-53 180.5 0.0 7.8e-24 84.0 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KEP61441.1 - 7.3e-06 25.3 0.0 0.0056 15.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KEP61441.1 - 0.036 13.6 0.0 7.9 6.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) FAD_binding_3 PF01494.14 KEP61442.1 - 7.5e-56 189.6 0.2 2.4e-30 105.7 0.1 3.3 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 KEP61442.1 - 4.6e-05 22.4 0.1 4.6e-05 22.4 0.1 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KEP61442.1 - 0.00027 20.8 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEP61442.1 - 0.0005 20.0 0.0 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEP61442.1 - 0.0012 17.8 0.1 0.002 17.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KEP61442.1 - 0.0077 14.7 0.1 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KEP61442.1 - 0.034 13.2 0.1 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 Thi4 family CENP-H PF05837.7 KEP61443.1 - 0.3 11.2 12.5 0.38 10.9 0.2 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF3123 PF11321.3 KEP61444.1 - 1.9 8.7 9.4 0.36 11.1 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Cofilin_ADF PF00241.15 KEP61446.1 - 2e-27 95.5 0.0 2.4e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PDEase_I PF00233.14 KEP61447.1 - 2.2e-46 158.5 0.4 6.3e-46 157.0 0.3 1.8 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CKS PF01111.14 KEP61449.1 - 4e-18 64.9 0.2 6.7e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit RNase_H PF00075.19 KEP61450.1 - 1.8e-18 67.1 0.1 2e-09 37.8 0.0 3.4 2 1 0 2 2 2 2 RNase H Snf7 PF03357.16 KEP61451.1 - 1.2e-18 67.0 13.1 1.7e-18 66.5 9.1 1.1 1 0 0 1 1 1 1 Snf7 DUF4476 PF14771.1 KEP61451.1 - 0.027 14.5 0.4 0.055 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) DUF4206 PF13901.1 KEP61451.1 - 0.028 13.9 4.1 0.043 13.3 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) KH_1 PF00013.24 KEP61454.1 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 KH domain FlhE PF06366.8 KEP61454.1 - 0.0085 15.9 0.1 2 8.2 0.0 2.3 2 0 0 2 2 2 2 Flagellar protein FlhE SEP PF08059.8 KEP61455.1 - 6e-22 77.7 0.0 1.4e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KEP61455.1 - 3.6e-14 52.5 0.0 6.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain AP2 PF00847.15 KEP61457.1 - 3.4e-07 30.2 0.3 0.00032 20.7 0.0 2.8 2 0 0 2 2 2 2 AP2 domain MtN3_slv PF03083.11 KEP61458.1 - 6.9e-17 61.0 6.1 5.5e-10 38.9 0.9 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange TauE PF01925.14 KEP61459.1 - 5.6e-09 35.7 25.9 0.00011 21.7 0.2 2.7 2 1 0 3 3 3 2 Sulfite exporter TauE/SafE DUF2721 PF11026.3 KEP61459.1 - 0.0048 16.5 0.1 0.0048 16.5 0.1 2.8 3 2 1 4 4 4 1 Protein of unknown function (DUF2721) DUF4381 PF14316.1 KEP61459.1 - 0.23 11.5 2.2 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) zf-C3HC4_3 PF13920.1 KEP61460.1 - 1.7e-12 46.7 12.5 2.2e-12 46.4 7.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP61460.1 - 0.00028 20.8 15.0 0.00063 19.7 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP61460.1 - 0.011 15.4 14.8 0.025 14.4 10.3 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 KEP61460.1 - 0.021 14.4 14.6 0.039 13.6 10.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KEP61460.1 - 0.14 11.7 6.5 0.27 10.8 4.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KEP61460.1 - 0.15 11.6 10.6 0.27 10.8 7.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CLPTM1 PF05602.7 KEP61461.1 - 0.64 8.6 0.8 1.3 7.6 0.5 1.4 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MFS_1 PF07690.11 KEP61462.1 - 1.3e-08 33.9 18.5 4.6e-06 25.5 2.1 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Ycf1 PF05758.7 KEP61462.1 - 0.02 12.6 0.1 0.027 12.1 0.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF3487 PF11990.3 KEP61462.1 - 1.4 8.3 0.0 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) PP2C PF00481.16 KEP61463.1 - 1.6e-43 148.9 0.3 6e-32 111.0 0.0 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.1 KEP61463.1 - 0.015 14.6 0.1 0.24 10.7 0.0 2.6 2 1 0 2 2 2 0 Protein phosphatase 2C Stm1_N PF09598.5 KEP61465.1 - 0.093 13.4 4.4 0.36 11.5 3.0 2.1 1 0 0 1 1 1 0 Stm1 zf-RING_2 PF13639.1 KEP61468.1 - 2e-09 37.1 5.7 4.6e-09 35.9 3.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP61468.1 - 2.2e-08 34.0 2.3 4e-08 33.2 1.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP61468.1 - 8.5e-07 28.5 5.4 1.5e-06 27.6 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEP61468.1 - 3.4e-06 26.8 1.4 9.2e-06 25.4 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KEP61468.1 - 0.00035 20.2 5.6 0.00079 19.1 3.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP61468.1 - 0.00042 20.2 6.8 0.00086 19.2 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP61468.1 - 0.0016 18.0 4.1 0.0033 17.0 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KEP61468.1 - 0.0058 16.6 2.7 0.011 15.6 1.8 1.5 1 0 0 1 1 1 1 RING-like domain Prok-RING_1 PF14446.1 KEP61468.1 - 0.008 15.8 1.6 0.008 15.8 1.1 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 RINGv PF12906.2 KEP61468.1 - 0.59 10.2 5.6 1.1 9.3 3.9 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 KEP61468.1 - 2.7 7.9 4.7 6.8 6.6 3.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CoA_binding_3 PF13727.1 KEP61468.1 - 9.3 6.0 8.5 0.42 10.4 1.6 1.9 2 0 0 2 2 2 0 CoA-binding domain DUF4490 PF14892.1 KEP61469.1 - 7.7e-09 35.1 0.1 1.4e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) TGT PF01702.13 KEP61471.1 - 1.9e-18 66.6 4.1 2.8e-17 62.8 2.8 2.4 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase NAD_kinase PF01513.16 KEP61472.1 - 7.8e-06 24.8 0.0 0.023 13.4 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.19 KEP61472.1 - 0.0027 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RNA_pol_Rbc25 PF08292.7 KEP61473.1 - 7.4e-28 97.1 0.0 1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KEP61473.1 - 8.5e-10 38.6 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RIIa PF02197.12 KEP61474.1 - 0.042 13.2 0.0 0.089 12.2 0.0 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit RNase_H2-Ydr279 PF09468.5 KEP61474.1 - 0.26 10.4 2.3 0.31 10.2 1.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SAG PF04092.8 KEP61476.1 - 4.3e-16 59.4 2.4 5e-16 59.2 1.7 1.1 1 0 0 1 1 1 1 SRS domain SAG PF04092.8 KEP61477.1 - 2.8e-45 153.6 20.7 5.4e-28 97.8 4.4 2.1 2 0 0 2 2 2 2 SRS domain WND PF07861.6 KEP61477.1 - 0.47 9.4 5.4 0.044 12.8 0.5 1.6 2 0 0 2 2 2 0 WisP family N-Terminal Region SAG PF04092.8 KEP61478.1 - 1.3e-42 145.1 18.9 1.2e-26 93.5 3.5 2.1 2 0 0 2 2 2 2 SRS domain Med13_C PF06333.7 KEP61479.1 - 0.12 10.9 0.6 0.13 10.7 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Med3 PF11593.3 KEP61479.1 - 0.72 9.0 2.9 0.84 8.8 2.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF605 PF04652.11 KEP61479.1 - 1.8 7.8 6.7 1.9 7.7 4.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 KEP61479.1 - 2.4 7.6 13.7 3 7.2 9.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) zf-C3HC4_3 PF13920.1 KEP61480.1 - 5.1 6.8 35.1 0.023 14.3 10.2 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) PCI PF01399.22 KEP61481.1 - 2e-20 73.0 0.1 6.5e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 KEP61481.1 - 1.7e-18 66.7 2.4 3.4e-18 65.7 1.6 1.4 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 KEP61481.1 - 0.0076 16.0 0.5 0.066 12.9 0.0 2.6 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 RRM_6 PF14259.1 KEP61482.1 - 9.6e-31 105.5 0.1 2.2e-12 46.7 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP61482.1 - 2.6e-30 103.8 0.1 4.6e-12 45.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP61482.1 - 6.5e-11 41.9 0.0 0.00068 19.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sre PF03125.13 KEP61482.1 - 7.4 5.3 0.7 11 4.7 0.5 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Fcf1 PF04900.7 KEP61483.1 - 6e-20 71.2 0.0 5e-11 42.5 0.0 2.6 2 0 0 2 2 2 2 Fcf1 bZIP_Maf PF03131.12 KEP61483.1 - 8.2 6.8 10.3 7.1 7.0 1.7 3.1 3 0 0 3 3 3 0 bZIP Maf transcription factor Ank_2 PF12796.2 KEP61484.1 - 7.7e-23 80.6 0.0 3.8e-16 59.1 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP61484.1 - 1.2e-18 67.0 0.0 2.8e-07 30.8 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEP61484.1 - 3.9e-16 58.7 1.1 4.3e-07 29.9 0.0 5.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KEP61484.1 - 1.4e-15 56.1 0.2 5.5e-07 29.0 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KEP61484.1 - 1.4e-13 49.6 0.0 0.00068 19.6 0.0 5.3 4 0 0 4 4 4 3 Ankyrin repeat TPR_16 PF13432.1 KEP61484.1 - 0.0012 19.4 1.5 0.0012 19.4 1.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP61484.1 - 0.027 14.8 1.4 0.067 13.5 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat BCIP PF13862.1 KEP61484.1 - 0.63 9.5 0.0 1.1 8.6 0.0 1.3 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Rtf2 PF04641.7 KEP61485.1 - 1.6e-52 178.2 0.8 2.5e-52 177.6 0.5 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KEP61485.1 - 0.0011 18.6 0.5 0.0042 16.7 0.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Cwf_Cwc_15 PF04889.7 KEP61485.1 - 0.013 15.2 1.1 0.025 14.3 0.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SIMPL PF04402.9 KEP61486.1 - 0.13 12.1 1.4 0.19 11.5 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF541) AATF-Che1 PF13339.1 KEP61486.1 - 0.32 11.1 2.4 1.3 9.1 0.2 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor PaREP1 PF05942.6 KEP61486.1 - 0.43 10.4 3.1 7.4 6.4 0.9 2.7 1 1 1 2 2 2 0 Archaeal PaREP1/PaREP8 family Pkinase PF00069.20 KEP61487.1 - 6.7e-58 195.8 0.0 9.4e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61487.1 - 7.6e-37 126.7 0.0 1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP61487.1 - 0.0046 15.9 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Ribosomal_L13 PF00572.13 KEP61488.1 - 9e-25 87.1 0.9 1.5e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 MORN PF02493.15 KEP61489.1 - 4.2e-49 161.4 71.6 5.6e-07 28.9 0.9 9.6 10 0 0 10 10 10 9 MORN repeat Form_Nir_trans PF01226.12 KEP61490.1 - 2.9e-73 245.8 19.4 3.5e-73 245.5 13.5 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter E1_dh PF00676.15 KEP61491.1 - 5.7e-80 268.2 0.1 7e-80 267.9 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KEP61491.1 - 0.011 14.7 0.1 0.046 12.6 0.0 1.7 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase tRNA-synt_1 PF00133.17 KEP61492.1 - 1.6e-37 128.8 0.2 5.6e-17 60.9 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEP61492.1 - 9.1e-20 70.6 0.1 2.9e-10 39.3 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEP61492.1 - 3.3e-14 52.9 0.1 1e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KEP61492.1 - 3.8e-13 49.2 0.1 2.1e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.20 KEP61493.1 - 3.8e-50 170.4 0.0 2.4e-17 62.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61493.1 - 7.6e-24 84.1 0.0 7.9e-20 71.0 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP61493.1 - 2.6e-14 51.3 0.0 4.3e-05 22.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KEP61493.1 - 9.3e-11 40.6 0.2 0.04 13.7 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KEP61493.1 - 1.6e-09 37.7 0.6 0.021 14.9 0.0 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 KEP61493.1 - 3e-09 36.3 0.4 0.018 14.6 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KEP61493.1 - 8.4e-07 28.0 0.6 0.016 14.5 0.0 3.5 3 0 0 3 3 3 2 EF hand SCRL PF06876.7 KEP61493.1 - 0.38 10.7 4.4 0.12 12.3 0.5 2.0 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein GCC2_GCC3 PF07699.8 KEP61495.1 - 2.2e-31 107.1 107.9 1.2e-08 34.3 5.0 11.4 10 1 1 11 11 11 8 GCC2 and GCC3 Lipoprotein_18 PF06804.6 KEP61495.1 - 0.74 8.5 0.0 1.3 7.6 0.0 1.3 1 0 0 1 1 1 0 NlpB/DapX lipoprotein PaaSYMP PF14738.1 KEP61495.1 - 1.8 8.2 0.4 3.7 7.2 0.3 1.4 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Vps26 PF03643.10 KEP61495.1 - 3.1 6.4 0.0 5.6 5.6 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 RRXRR PF14239.1 KEP61495.1 - 6.9 6.0 0.3 15 4.9 0.2 1.5 1 0 0 1 1 1 0 RRXRR protein Spore_III_AF PF09581.5 KEP61495.1 - 7.7 6.3 0.0 14 5.4 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TFIIB PF00382.14 KEP61496.1 - 2.8e-14 52.6 0.7 1.8e-06 27.6 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KEP61496.1 - 7.8e-10 37.9 0.6 1.4e-09 37.1 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 KEP61496.1 - 0.00012 21.9 0.0 0.002 18.0 0.0 2.2 1 1 1 2 2 2 1 Cyclin, C-terminal domain zinc_ribbon_2 PF13240.1 KEP61496.1 - 2.3 7.8 4.2 2.5 7.7 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PLRV_ORF5 PF01690.12 KEP61496.1 - 4.3 6.3 11.0 0.42 9.7 3.1 2.0 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein mTERF PF02536.9 KEP61497.1 - 9.7e-12 44.1 0.2 3.3e-11 42.3 0.2 1.8 2 0 0 2 2 2 1 mTERF HECT PF00632.20 KEP61498.1 - 2.6e-67 227.2 0.0 6.1e-67 226.0 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Herpes_UL37_1 PF03970.8 KEP61498.1 - 2.1 7.0 0.0 4.1 6.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein UME PF08064.8 KEP61498.1 - 2.8 7.9 0.1 7 6.6 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain Kinase-like PF14531.1 KEP61499.1 - 8.8e-17 60.9 0.0 1.2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.17 KEP61500.1 - 4.4e-23 80.6 0.0 2e-13 49.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP61500.1 - 3.5e-11 42.9 0.0 4.2e-06 26.6 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP61500.1 - 9.7e-09 34.9 0.0 0.031 14.1 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FA_desaturase PF00487.19 KEP61501.1 - 0.12 11.8 3.0 0.21 10.9 0.0 2.5 3 0 0 3 3 3 0 Fatty acid desaturase RRM_1 PF00076.17 KEP61502.1 - 1e-39 134.0 0.4 3.9e-19 68.0 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP61502.1 - 7.4e-35 118.7 0.0 6.6e-17 61.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP61502.1 - 5.1e-26 90.2 0.1 3.9e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEP61502.1 - 2e-05 24.2 0.0 0.0083 15.8 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif AAA_23 PF13476.1 KEP61503.1 - 0.0094 16.2 8.0 0.015 15.6 5.6 1.3 1 0 0 1 1 1 1 AAA domain DUF1049 PF06305.6 KEP61503.1 - 0.048 13.1 0.7 0.048 13.1 0.5 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) DUF1634 PF07843.6 KEP61503.1 - 0.05 13.2 0.2 1.1 8.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1634) KorB_C PF06613.6 KEP61503.1 - 0.099 12.0 0.2 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain DUF3040 PF11239.3 KEP61503.1 - 0.1 12.6 0.2 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF202 PF02656.10 KEP61503.1 - 0.21 11.8 0.9 4.8 7.4 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Rgp1 PF08737.5 KEP61503.1 - 0.68 8.9 6.0 1.1 8.2 4.1 1.3 1 0 0 1 1 1 0 Rgp1 DUF4407 PF14362.1 KEP61503.1 - 5 5.9 14.4 0.82 8.5 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RNase_H2-Ydr279 PF09468.5 KEP61504.1 - 2.4e-13 49.9 0.0 2.4e-13 49.9 0.0 3.2 2 2 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) TgMIC1 PF11476.3 KEP61505.1 - 2.5e-71 237.5 2.8 3.7e-71 237.0 1.9 1.3 1 0 0 1 1 1 1 Toxoplasma gondii micronemal protein 1 TgMIC1 MAR_sialic_bdg PF10564.4 KEP61505.1 - 1.6e-32 111.1 14.2 5.2e-24 83.8 2.5 3.0 2 1 1 3 3 3 2 Sialic-acid binding micronemal adhesive repeat Trypan_PARP PF05887.6 KEP61505.1 - 0.9 9.3 6.5 0.65 9.7 3.5 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Metallothio_PEC PF02068.11 KEP61505.1 - 8.9 6.7 18.0 0.2 12.0 1.3 3.1 3 0 0 3 3 3 0 Plant PEC family metallothionein DivIC PF04977.10 KEP61506.1 - 0.04 13.4 0.2 0.067 12.6 0.2 1.2 1 0 0 1 1 1 0 Septum formation initiator HORMA PF02301.13 KEP61507.1 - 8.4e-40 136.4 0.0 1.2e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Rrf2 PF02082.15 KEP61507.1 - 0.0054 16.8 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 2 Transcriptional regulator EAP30 PF04157.11 KEP61507.1 - 0.013 14.7 0.1 2.4 7.2 0.0 2.5 2 0 0 2 2 2 0 EAP30/Vps36 family SgrR_N PF12793.2 KEP61507.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term Helicase_IV_N PF12462.3 KEP61507.1 - 0.026 14.1 0.8 0.079 12.6 0.2 2.0 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal Ribosomal_S25 PF03297.10 KEP61507.1 - 0.11 12.5 0.0 6.9 6.7 0.0 2.6 2 0 0 2 2 2 0 S25 ribosomal protein Ribosomal_S30 PF04758.9 KEP61508.1 - 1.3e-27 95.3 11.7 1.4e-27 95.1 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Endosulfine PF04667.12 KEP61508.1 - 0.094 12.6 1.3 0.12 12.3 0.9 1.1 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region MRP-S31 PF15433.1 KEP61509.1 - 0.14 11.5 10.9 0.17 11.2 7.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Prominin PF05478.6 KEP61509.1 - 0.34 8.4 3.0 0.41 8.1 2.1 1.2 1 0 0 1 1 1 0 Prominin APG6 PF04111.7 KEP61509.1 - 0.43 9.5 8.9 0.67 8.9 6.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1664 PF07889.7 KEP61509.1 - 0.68 9.7 5.6 0.27 11.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Band_3_cyto PF07565.8 KEP61509.1 - 1 8.7 7.6 1.3 8.5 5.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spore_III_AB PF09548.5 KEP61509.1 - 2.8 7.6 6.8 43 3.8 4.7 2.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Seryl_tRNA_N PF02403.17 KEP61509.1 - 4.3 7.3 11.6 10 6.2 7.7 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EF-hand_like PF09279.6 KEP61510.1 - 0.0075 16.2 0.1 2.3 8.2 0.0 3.0 2 0 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like FliT PF05400.8 KEP61510.1 - 0.085 13.2 7.7 1.8 9.0 0.0 4.7 4 1 0 5 5 5 0 Flagellar protein FliT Baculo_PEP_C PF04513.7 KEP61510.1 - 0.2 11.4 3.8 6.6 6.5 0.1 3.7 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Taxilin PF09728.4 KEP61510.1 - 0.32 10.0 8.4 0.13 11.2 0.2 3.2 3 0 0 3 3 3 0 Myosin-like coiled-coil protein AAA_12 PF13087.1 KEP61511.1 - 5.3e-58 195.7 0.0 1e-57 194.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 KEP61511.1 - 1.8e-56 189.9 5.9 3.2e-56 189.1 4.1 1.4 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 KEP61511.1 - 1.5e-54 185.0 0.1 2.2e-54 184.5 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP61511.1 - 1.4e-12 47.1 0.1 4.9e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KEP61511.1 - 1.7e-10 40.8 0.0 4e-09 36.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KEP61511.1 - 8.4e-05 22.1 0.1 0.00055 19.4 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEP61511.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KEP61511.1 - 0.004 16.1 0.7 0.017 14.1 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KEP61511.1 - 0.0064 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KEP61511.1 - 0.02 14.1 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 KEP61511.1 - 0.028 14.6 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S13_N PF08069.7 KEP61511.1 - 0.048 13.4 0.6 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain UvrD-helicase PF00580.16 KEP61511.1 - 0.056 12.7 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KEP61511.1 - 0.085 12.3 0.4 19 4.6 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase EutB PF06751.6 KEP61511.1 - 0.092 11.0 0.1 0.14 10.4 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) Thioredoxin PF00085.15 KEP61512.1 - 4.8e-08 32.6 0.2 1.2e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin DUF1414 PF07208.6 KEP61512.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) Arf PF00025.16 KEP61513.1 - 2.3e-30 105.1 0.0 2.6e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEP61513.1 - 0.00041 19.7 0.0 0.00052 19.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KEP61513.1 - 0.0011 18.2 0.0 0.014 14.6 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KEP61513.1 - 0.0075 15.7 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Usp PF00582.21 KEP61513.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Universal stress protein family Miro PF08477.8 KEP61513.1 - 0.02 15.4 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Gtr1_RagA PF04670.7 KEP61513.1 - 0.052 12.6 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Sec23_trunk PF04811.10 KEP61515.1 - 4.2e-59 199.8 0.0 5.8e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEP61515.1 - 2.2e-31 107.3 1.7 5.2e-31 106.1 0.7 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KEP61515.1 - 1.8e-29 102.0 0.1 3.7e-29 101.0 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEP61515.1 - 3.4e-14 52.0 4.2 6.8e-14 51.1 2.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KEP61515.1 - 5.7e-13 48.3 0.1 2.3e-12 46.3 0.0 2.0 2 1 0 2 2 2 1 Gelsolin repeat MutS_IV PF05190.13 KEP61515.1 - 0.038 14.1 0.1 0.47 10.6 0.0 2.6 2 0 0 2 2 2 0 MutS family domain IV DEAD PF00270.24 KEP61516.1 - 1.3e-26 93.0 0.0 3.5e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP61516.1 - 4e-14 52.2 0.0 9.9e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEP61516.1 - 0.0097 14.7 0.0 0.017 13.9 0.0 1.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain CENP-F_leu_zip PF10473.4 KEP61517.1 - 0.033 14.0 27.2 0.18 11.6 3.5 2.8 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cas_Cas4 PF01930.12 KEP61517.1 - 0.041 13.8 5.7 0.028 14.3 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF83 GAS PF13851.1 KEP61517.1 - 0.044 12.9 23.8 0.041 13.0 2.6 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KEP61517.1 - 0.05 13.1 0.7 0.05 13.1 0.5 4.7 3 2 2 5 5 5 0 Septum formation initiator APG6 PF04111.7 KEP61517.1 - 0.087 11.8 22.2 0.65 8.9 2.8 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 KEP61517.1 - 0.3 9.6 20.4 0.7 8.4 3.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Noelin-1 PF12308.3 KEP61517.1 - 0.47 10.2 7.8 2.4 8.0 0.6 3.0 2 1 1 3 3 3 0 Neurogenesis glycoprotein Reo_sigmaC PF04582.7 KEP61517.1 - 0.71 8.9 15.2 0.2 10.7 5.1 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 KEP61517.1 - 0.97 9.4 19.7 3 7.8 0.2 4.4 4 1 1 5 5 4 0 bZIP transcription factor DUF904 PF06005.7 KEP61517.1 - 1.2 9.4 25.2 2.9 8.2 0.0 4.1 3 2 2 5 5 4 0 Protein of unknown function (DUF904) Atg14 PF10186.4 KEP61517.1 - 2.1 7.2 30.1 0.015 14.2 6.5 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KEP61517.1 - 2.2 7.6 26.1 88 2.4 18.1 2.2 1 1 0 1 1 1 0 Intermediate filament protein CLP_protease PF00574.18 KEP61517.1 - 2.3 7.8 9.3 12 5.5 1.0 3.2 3 1 0 3 3 3 0 Clp protease IncA PF04156.9 KEP61517.1 - 2.4 7.7 32.4 3.7 7.0 7.8 2.4 2 1 0 2 2 2 0 IncA protein Mnd1 PF03962.10 KEP61517.1 - 3.1 7.4 23.2 3.2 7.3 3.9 2.2 2 0 0 2 2 2 0 Mnd1 family DUF940 PF06082.6 KEP61517.1 - 3.1 6.2 8.3 0.74 8.2 0.1 2.0 1 1 1 2 2 2 0 Bacterial putative lipoprotein (DUF940) NPV_P10 PF05531.7 KEP61517.1 - 4.3 7.6 12.2 4.4 7.6 0.4 4.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2400 PF09674.5 KEP61517.1 - 4.8 6.8 9.5 0.95 9.1 1.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2400) DUF1664 PF07889.7 KEP61517.1 - 5.7 6.7 11.7 0.35 10.6 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.7 KEP61517.1 - 6.3 6.5 16.2 0.1 12.3 1.2 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.6 KEP61517.1 - 6.4 6.7 13.2 43 4.1 0.3 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) GP41 PF00517.12 KEP61517.1 - 7 6.1 9.2 5.1 6.6 2.1 2.3 2 0 0 2 2 2 0 Retroviral envelope protein Mut7-C PF01927.11 KEP61517.1 - 8.5 6.3 11.7 0.54 10.2 2.5 2.2 1 1 1 2 2 2 0 Mut7-C RNAse domain OTCace PF00185.19 KEP61519.1 - 6.2e-36 123.6 0.0 9.7e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 KEP61519.1 - 1e-33 116.0 0.0 1.8e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF462 PF04315.7 KEP61520.1 - 0.0013 18.1 0.2 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF462 PA26 PF04636.8 KEP61520.1 - 0.0019 16.9 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF4131 PF13567.1 KEP61520.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pex19 PF04614.7 KEP61520.1 - 0.65 9.5 4.7 0.49 9.9 1.8 1.8 1 1 0 1 1 1 0 Pex19 protein family DUF1635 PF07795.6 KEP61521.1 - 0.00012 21.5 6.0 0.00012 21.5 4.2 5.6 4 1 1 5 5 5 1 Protein of unknown function (DUF1635) Syntaxin PF00804.20 KEP61522.1 - 0.037 14.2 3.1 0.038 14.1 0.3 2.1 2 0 0 2 2 2 0 Syntaxin DASH_Duo1 PF08651.5 KEP61522.1 - 0.087 12.4 1.8 0.72 9.4 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Atg14 PF10186.4 KEP61522.1 - 2.6 6.8 14.4 0.04 12.8 3.7 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 KEP61522.1 - 4.5 7.0 10.4 0.36 10.5 1.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KEP61522.1 - 6.6 5.6 7.3 1.2 8.0 0.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Jiraiya PF15038.1 KEP61523.1 - 0.054 12.9 8.1 0.095 12.1 5.6 1.4 1 1 0 1 1 1 0 Jiraiya KH_1 PF00013.24 KEP61525.1 - 6.4e-31 105.7 0.7 1.1e-08 34.5 0.2 5.6 5 1 0 5 5 5 4 KH domain KH_3 PF13014.1 KEP61525.1 - 8.6e-20 69.9 0.1 0.00027 20.5 0.0 6.1 6 0 0 6 6 6 4 KH domain BMC PF00936.14 KEP61525.1 - 0.0007 19.2 0.0 0.73 9.5 0.0 3.7 3 0 0 3 3 3 2 BMC domain KIAA1430 PF13879.1 KEP61526.1 - 7.9e-13 48.6 5.8 1.6e-12 47.6 4.0 1.5 1 0 0 1 1 1 1 KIAA1430 homologue HlyIII PF03006.15 KEP61527.1 - 5.2e-22 78.3 19.9 6.2e-22 78.0 13.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DPM2 PF07297.7 KEP61528.1 - 0.076 13.3 0.1 0.092 13.0 0.1 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) N2227 PF07942.7 KEP61529.1 - 6.3e-91 304.0 0.0 8.6e-91 303.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.7 KEP61529.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEP61529.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 KEP61530.1 - 2.3e-16 59.7 0.0 2.4e-11 43.4 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP61530.1 - 0.00031 20.5 0.0 0.00083 19.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BTB_2 PF02214.17 KEP61532.1 - 1.8e-16 60.0 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain AIG2 PF06094.7 KEP61537.1 - 2e-14 53.9 0.1 6.1e-13 49.1 0.0 2.4 1 1 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 KEP61537.1 - 0.099 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AIG2-like family Arf PF00025.16 KEP61538.1 - 1.9e-25 89.1 0.0 1.4e-16 60.2 0.0 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family G-alpha PF00503.15 KEP61538.1 - 2.8e-08 32.8 3.5 0.0017 17.1 0.0 2.9 3 0 0 3 3 3 2 G-protein alpha subunit AAA_33 PF13671.1 KEP61538.1 - 0.00058 19.7 1.0 0.011 15.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KEP61538.1 - 0.0043 16.7 0.0 0.54 9.9 0.0 3.0 3 0 0 3 3 3 1 NACHT domain SRPRB PF09439.5 KEP61538.1 - 0.01 15.0 0.0 0.52 9.5 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KEP61538.1 - 0.013 16.0 0.0 1 9.9 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein SRP54 PF00448.17 KEP61538.1 - 0.022 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 KEP61538.1 - 0.028 14.5 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 KEP61538.1 - 0.031 13.6 0.0 1.2 8.4 0.0 2.8 2 1 0 2 2 2 0 Ras family Thymidylate_kin PF02223.12 KEP61538.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase ABC_tran PF00005.22 KEP61538.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 KEP61538.1 - 0.066 13.1 0.0 0.27 11.1 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 KEP61538.1 - 0.12 11.8 0.1 0.53 9.6 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KEP61538.1 - 0.2 11.3 0.0 0.43 10.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 KEP61538.1 - 0.25 10.4 0.0 21 4.1 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MoaC PF01967.16 KEP61540.1 - 3.5e-42 143.2 1.6 9.2e-36 122.5 0.6 3.1 2 1 0 2 2 2 2 MoaC family Hyphal_reg_CWP PF11765.3 KEP61540.1 - 0.079 11.7 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal C2 PF00168.25 KEP61541.1 - 6.7e-09 35.4 0.3 9.9e-08 31.7 0.1 3.1 3 0 0 3 3 3 1 C2 domain AP2 PF00847.15 KEP61542.1 - 0.0018 18.3 0.1 0.0018 18.3 0.1 2.2 3 0 0 3 3 3 1 AP2 domain PFK PF00365.15 KEP61543.1 - 2.3e-34 118.6 0.0 1.4e-23 83.2 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase Herpes_UL6 PF01763.11 KEP61544.1 - 0.34 9.0 0.0 0.53 8.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DivIC PF04977.10 KEP61544.1 - 2.1 7.8 3.6 4.2 6.9 2.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Adaptin_N PF01602.15 KEP61546.1 - 3.7e-157 523.8 13.7 4.6e-157 523.5 9.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KEP61546.1 - 2.1e-29 102.5 3.6 3.5e-27 95.4 0.0 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEP61546.1 - 1e-22 80.2 4.0 8e-11 42.0 0.0 6.0 1 1 5 6 6 6 5 HEAT repeats B2-adapt-app_C PF09066.5 KEP61546.1 - 7.7e-17 61.2 0.2 1.6e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.17 KEP61546.1 - 1.8e-10 39.9 4.1 0.0037 17.2 0.0 5.5 6 0 0 6 6 5 2 HEAT repeat Arm PF00514.18 KEP61546.1 - 1.4e-06 27.8 2.0 0.0034 17.1 0.0 5.0 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KEP61546.1 - 7.7e-06 26.2 4.1 0.15 12.6 0.0 4.7 4 1 0 4 4 4 2 HEAT-like repeat Cnd3 PF12719.2 KEP61546.1 - 1.2e-05 24.4 2.3 0.00014 20.9 0.3 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 KEP61546.1 - 0.00096 18.5 8.4 0.9 8.8 0.0 4.9 4 1 1 5 5 5 2 CLASP N terminal Sec7_N PF12783.2 KEP61546.1 - 0.0033 16.8 0.1 0.01 15.2 0.1 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm_2 PF04826.8 KEP61546.1 - 0.0045 16.1 0.0 0.016 14.2 0.0 1.9 1 0 0 1 1 1 1 Armadillo-like PP1_bind PF15276.1 KEP61546.1 - 0.013 15.5 1.0 0.94 9.5 0.1 3.0 2 0 0 2 2 2 0 Protein phosphatase 1 binding Alpha_adaptinC2 PF02883.15 KEP61546.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain RasGEF_N_2 PF14663.1 KEP61546.1 - 0.056 13.3 0.6 4 7.4 0.0 3.6 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Integrin_alpha PF00357.15 KEP61547.1 - 2.3 8.2 4.6 9.6 6.2 3.2 2.1 1 1 0 1 1 1 0 Integrin alpha cytoplasmic region Acyltransferase PF01553.16 KEP61548.1 - 1.6e-21 76.1 0.0 2.3e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.27 KEP61549.1 - 7.7e-10 38.2 0.9 0.022 14.6 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 KEP61549.1 - 0.0025 16.0 0.2 0.0056 14.8 0.1 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEP61549.1 - 0.038 12.7 0.0 0.23 10.1 0.0 2.1 2 1 0 2 2 2 0 Nup133 N terminal like Nucleoplasmin PF03066.10 KEP61549.1 - 0.2 11.1 3.1 0.54 9.7 0.3 2.6 3 0 0 3 3 3 0 Nucleoplasmin Myc_N PF01056.13 KEP61549.1 - 0.73 8.9 8.2 0.052 12.7 2.0 1.7 2 0 0 2 2 2 0 Myc amino-terminal region FAM176 PF14851.1 KEP61549.1 - 5.3 6.7 6.7 9.3 5.9 2.7 2.2 2 0 0 2 2 2 0 FAM176 family Cupin_4 PF08007.7 KEP61550.1 - 1.9e-30 106.2 0.0 1.6e-28 99.9 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.1 KEP61550.1 - 0.00018 21.0 0.0 0.002 17.7 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 KEP61550.1 - 0.036 13.5 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Cupin_1 PF00190.17 KEP61550.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Cupin Abhydrolase_6 PF12697.2 KEP61551.1 - 1.4e-22 80.7 3.4 3.3e-22 79.5 2.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP61551.1 - 9.6e-10 38.3 0.2 1e-08 35.0 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEP61551.1 - 7.7e-07 28.9 0.0 6.9e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEP61551.1 - 0.076 12.5 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein DUF676 PF05057.9 KEP61551.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) OAD_gamma PF04277.8 KEP61553.1 - 0.0011 19.3 0.0 0.0014 18.9 0.0 1.1 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Sex_peptide PF08138.6 KEP61553.1 - 0.033 14.0 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Sex peptide (SP) family Sigma_reg_N PF13800.1 KEP61553.1 - 0.039 13.9 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Tad PF13400.1 KEP61553.1 - 0.059 13.4 0.4 0.07 13.1 0.3 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like PsbN PF02468.10 KEP61553.1 - 1.7 8.2 4.2 2.3 7.8 2.9 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) MORN PF02493.15 KEP61554.1 - 2e-21 74.3 31.2 2.7e-05 23.6 0.8 6.8 7 0 0 7 7 7 6 MORN repeat Dynein_light PF01221.13 KEP61555.1 - 2.8e-15 56.0 0.0 3.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Cyt-b5 PF00173.23 KEP61557.1 - 3.6e-12 45.9 0.0 6.6e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KEP61557.1 - 1.1e-08 35.4 16.0 2.8e-08 34.1 11.1 1.7 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 KEP61557.1 - 0.0045 16.9 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Sec1 PF00995.18 KEP61558.1 - 2e-112 376.7 0.0 2.2e-112 376.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF488 PF04343.8 KEP61558.1 - 0.0068 16.7 0.5 0.021 15.1 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF488 MgtE PF01769.11 KEP61559.1 - 0.0062 16.8 3.1 0.11 12.7 0.2 2.1 2 0 0 2 2 2 2 Divalent cation transporter SHD1 PF03983.7 KEP61559.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Peptidase_M50 PF02163.17 KEP61559.1 - 0.11 11.3 0.7 0.16 10.9 0.5 1.3 1 0 0 1 1 1 0 Peptidase family M50 RRM_1 PF00076.17 KEP61560.1 - 2.1e-16 59.3 0.0 2.4e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 KEP61560.1 - 9.1e-16 57.2 0.1 1.6e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 KEP61560.1 - 3.6e-10 39.5 0.0 7.5e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP61560.1 - 2.6e-08 33.7 0.0 7.7e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 KEP61560.1 - 0.03 13.9 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 ubiquitin PF00240.18 KEP61561.1 - 8.5e-13 47.5 0.0 1.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KEP61561.1 - 4.3e-08 32.7 0.1 2.5e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KEP61561.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEP61561.1 - 0.00086 19.5 0.0 0.0024 18.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain UBA_4 PF14555.1 KEP61561.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain S-AdoMet_synt_C PF02773.11 KEP61562.1 - 4e-64 214.4 0.0 6.1e-64 213.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KEP61562.1 - 8e-49 164.5 0.0 1.7e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KEP61562.1 - 3.8e-43 145.7 0.4 6.4e-43 145.0 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Rdx PF10262.4 KEP61563.1 - 2.8e-05 24.0 0.1 3.2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Rdx family TPM PF04536.9 KEP61564.1 - 8.9e-09 35.2 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Fer2 PF00111.22 KEP61565.1 - 8e-13 47.9 3.0 1.2e-12 47.3 2.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RBD PF02196.10 KEP61565.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain Fer2_4 PF13510.1 KEP61565.1 - 0.2 11.5 1.4 0.54 10.1 1.0 1.9 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2361 PF10153.4 KEP61566.1 - 1.9e-12 47.3 10.6 1.9e-12 47.3 7.4 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF3619 PF12279.3 KEP61566.1 - 1.3 9.1 6.1 0.28 11.2 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) FUSC PF04632.7 KEP61566.1 - 2.9 6.1 3.8 2.4 6.4 1.6 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family Coatomer_WDAD PF04053.9 KEP61567.1 - 5.5e-101 338.5 0.0 9.9e-101 337.6 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KEP61567.1 - 2.1e-58 197.8 0.0 3.9e-58 196.9 0.0 1.3 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KEP61567.1 - 2.5e-56 185.6 10.8 9.7e-10 37.9 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEP61567.1 - 0.00017 20.4 0.3 0.072 11.8 0.1 3.1 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KEP61567.1 - 0.0091 14.1 8.2 1.7 6.7 0.0 4.2 2 1 2 4 4 4 3 Nucleoporin Nup120/160 ENTH PF01417.15 KEP61567.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 ENTH domain TPR_16 PF13432.1 KEP61567.1 - 0.043 14.5 10.3 4.5 8.0 3.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KEP61568.1 - 4.6e-37 127.5 0.0 5.7e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61568.1 - 1.3e-15 57.2 0.0 1.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP61568.1 - 2.3e-05 24.2 0.0 0.0004 20.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEP61568.1 - 0.0068 15.2 0.1 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 KEP61569.1 - 3e-59 200.2 0.0 5.8e-49 166.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61569.1 - 1.4e-33 116.0 0.0 2.5e-27 95.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEP61569.1 - 4.2e-06 25.9 0.1 4.3e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP61569.1 - 0.0083 15.8 0.0 0.097 12.3 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP61569.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 KEP61569.1 - 0.17 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4164 PF13747.1 KEP61570.1 - 0.074 13.1 0.4 0.082 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Cpn60_TCP1 PF00118.19 KEP61572.1 - 2.7e-101 339.6 0.1 8e-101 338.0 0.1 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_Rpb5_C PF01191.14 KEP61573.1 - 1.4e-35 120.6 0.4 2.7e-35 119.8 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KEP61573.1 - 8.8e-24 83.7 1.1 1.4e-23 83.0 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KEP61573.1 - 0.00026 20.7 0.1 0.00067 19.4 0.1 1.7 1 1 0 1 1 1 1 Restriction endonuclease SseB PF07179.7 KEP61573.1 - 0.097 12.4 0.1 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 SseB protein N-terminal domain DUF4174 PF13778.1 KEP61573.1 - 0.14 12.2 0.7 0.62 10.1 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) TP6A_N PF04406.9 KEP61575.1 - 2e-12 46.5 1.3 3.6e-12 45.7 0.9 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 KEP61575.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) SidE PF12252.3 KEP61575.1 - 0.065 10.5 0.0 0.091 10.0 0.0 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein MAPEG PF01124.13 KEP61577.1 - 2.2e-19 69.3 1.2 3.3e-19 68.7 0.8 1.3 1 0 0 1 1 1 1 MAPEG family COX17 PF05051.8 KEP61578.1 - 7.6e-22 77.0 7.5 7.6e-22 77.0 5.2 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cys_rich_VLP PF14194.1 KEP61578.1 - 2.2 8.0 7.1 3.5 7.4 4.9 1.4 1 1 0 1 1 1 0 Cysteine-rich VLP Dor1 PF04124.7 KEP61579.1 - 7e-30 103.6 0.7 1.1e-29 102.9 0.5 1.3 1 0 0 1 1 1 1 Dor1-like family COG2 PF06148.6 KEP61579.1 - 0.057 13.2 0.9 1.7 8.4 0.2 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 KEP61579.1 - 0.11 12.8 0.5 0.47 10.7 0.0 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Gp-FAR-1 PF05823.7 KEP61580.1 - 0.69 9.8 6.0 0.23 11.3 1.6 1.9 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PLRV_ORF5 PF01690.12 KEP61580.1 - 2.5 7.1 5.8 3.2 6.7 4.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Flg_bb_rod PF00460.15 KEP61580.1 - 3.7 7.3 7.6 0.26 11.0 1.1 2.3 2 0 0 2 2 2 0 Flagella basal body rod protein Oligomerisation PF02410.10 KEP61582.1 - 3.2e-13 49.5 0.0 6.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Oligomerisation domain Ribosomal_L39 PF00832.15 KEP61582.1 - 0.16 11.4 3.0 1.2 8.6 2.1 2.1 2 0 0 2 2 2 0 Ribosomal L39 protein PITH PF06201.8 KEP61584.1 - 1.3e-29 102.9 0.1 3.3e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 PITH domain MCR_alpha PF02249.12 KEP61584.1 - 0.075 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain CPW_WPC PF09717.5 KEP61586.1 - 5.6e-29 100.5 12.3 1.9e-15 57.1 3.3 2.1 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) AP2 PF00847.15 KEP61588.1 - 2.4e-14 53.2 11.0 3.3e-07 30.3 0.3 2.7 3 0 0 3 3 3 2 AP2 domain Maf PF02545.9 KEP61589.1 - 4.6e-33 114.0 0.0 2.7e-32 111.4 0.0 1.8 1 1 0 1 1 1 1 Maf-like protein Cauli_VI PF01693.11 KEP61589.1 - 0.00072 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Glyoxalase_2 PF12681.2 KEP61591.1 - 5e-08 33.5 0.0 0.024 15.2 0.0 3.3 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 KEP61591.1 - 2.8e-06 27.3 0.0 2.9e-05 24.0 0.0 2.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase PF00069.20 KEP61592.1 - 4.7e-37 127.5 0.0 2.6e-22 79.2 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61592.1 - 8.1e-20 70.9 0.0 7.1e-12 44.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP61592.1 - 0.063 12.2 0.0 0.95 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.6 KEP61592.1 - 0.92 8.2 0.0 1.4 7.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KEP61592.1 - 8.4 5.0 0.1 12 4.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase rRNA_processing PF08524.6 KEP61593.1 - 2.4e-06 27.4 18.7 2.4e-06 27.4 13.0 4.3 3 3 0 3 3 3 1 rRNA processing Ebola_NP PF05505.7 KEP61593.1 - 3 5.8 18.2 2.8 5.9 11.2 1.5 1 1 1 2 2 2 0 Ebola nucleoprotein Pkinase PF00069.20 KEP61594.1 - 2e-54 184.4 0.0 1.7e-40 138.8 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61594.1 - 7.1e-22 77.7 0.0 4.3e-20 71.8 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP61594.1 - 2.5e-18 63.8 3.0 7.8e-05 21.7 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 KEP61594.1 - 6.5e-15 53.7 2.1 1.1e-05 24.5 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KEP61594.1 - 1.1e-14 54.2 2.6 3.7e-07 30.1 0.0 4.1 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KEP61594.1 - 2.3e-14 51.9 4.1 0.00016 21.2 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KEP61594.1 - 7.8e-11 41.4 7.0 0.04 13.5 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain pair Kdo PF06293.9 KEP61594.1 - 0.0038 16.3 0.0 0.011 14.8 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 KEP61594.1 - 1.4 8.6 1.4 25 4.6 0.0 3.0 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand eIF3_p135 PF12807.2 KEP61595.1 - 1.7e-11 44.3 0.0 3.9e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KEP61595.1 - 0.00017 21.4 0.2 0.27 11.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KEP61595.1 - 0.02 14.9 0.1 0.3 11.2 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CLU PF13236.1 KEP61595.1 - 1.1 8.6 0.0 2.6 7.4 0.0 1.6 1 0 0 1 1 1 0 Clustered mitochondria E1_dh PF00676.15 KEP61596.1 - 6.6e-79 264.7 0.0 8.1e-79 264.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 KEP61596.1 - 0.00043 19.2 0.0 0.00077 18.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 KEP61596.1 - 0.00048 19.1 0.0 0.0012 17.8 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Proteasome PF00227.21 KEP61597.1 - 2.3e-58 196.6 0.0 2.9e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEP61597.1 - 1.5e-14 53.0 0.4 2.6e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature START PF01852.14 KEP61598.1 - 0.00015 21.1 0.0 0.00041 19.7 0.0 1.8 1 1 0 1 1 1 1 START domain Rabaptin PF03528.10 KEP61599.1 - 9.5 6.1 9.7 4.5 7.2 1.0 2.8 2 0 0 2 2 2 0 Rabaptin Aminotran_5 PF00266.14 KEP61600.1 - 2.9e-38 131.5 0.0 3.6e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KEP61600.1 - 0.00024 20.1 0.0 0.0018 17.2 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEP61600.1 - 0.019 13.9 0.0 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family CDC50 PF03381.10 KEP61601.1 - 3.7e-67 226.4 0.0 4.9e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Neurensin PF14927.1 KEP61601.1 - 0.18 11.1 0.5 2.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Neurensin Robl_LC7 PF03259.12 KEP61602.1 - 1.5e-11 43.6 0.0 1.8e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Myosin_head PF00063.16 KEP61603.1 - 6.8e-178 592.8 0.1 1e-177 592.3 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Ran_BP1 PF00638.13 KEP61603.1 - 0.0094 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain DUF258 PF03193.11 KEP61603.1 - 0.024 13.8 0.1 0.078 12.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEP61603.1 - 0.036 14.1 0.0 0.23 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEP61603.1 - 0.091 11.8 0.1 0.25 10.4 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin Mononeg_mRNAcap PF14318.1 KEP61604.1 - 0.59 9.1 2.8 0.49 9.3 0.7 1.7 2 0 0 2 2 2 0 Mononegavirales mRNA-capping region V WD40 PF00400.27 KEP61606.1 - 1.5e-24 84.8 16.3 4.5e-11 42.1 0.1 6.6 5 2 0 5 5 5 4 WD domain, G-beta repeat UTP15_C PF09384.5 KEP61606.1 - 2.8e-22 79.0 1.1 4.2e-22 78.4 0.7 1.3 1 0 0 1 1 1 1 UTP15 C terminal Cytochrom_D1 PF02239.11 KEP61606.1 - 0.014 13.7 0.0 0.022 13.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain FAM176 PF14851.1 KEP61606.1 - 0.029 14.0 1.4 0.15 11.7 1.5 1.7 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.6 KEP61606.1 - 0.052 13.3 2.5 0.13 12.0 1.7 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Utp13 PF08625.6 KEP61606.1 - 0.11 12.0 0.7 0.27 10.8 0.5 1.6 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain BLVR PF06375.6 KEP61606.1 - 1.8 8.3 8.0 0.053 13.3 1.1 1.7 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Kinase-like PF14531.1 KEP61607.1 - 1.2e-94 316.5 0.0 1.5e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP61607.1 - 2.9e-06 26.6 0.0 4.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain 5_nucleotid_C PF02872.13 KEP61609.1 - 2.3e-32 112.1 0.0 4.8e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KEP61609.1 - 6.2e-07 29.0 0.0 1.4e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase dCMP_cyt_deam_1 PF00383.17 KEP61610.1 - 1.7e-19 69.3 7.6 1.8e-12 46.7 0.4 2.5 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KEP61610.1 - 2.8e-18 66.1 0.0 1.8e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Med27 PF11571.3 KEP61610.1 - 0.034 14.2 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 27 LmjF365940-deam PF14421.1 KEP61610.1 - 0.3 10.4 13.0 0.35 10.2 0.2 3.2 2 2 0 3 3 3 0 A distinct subfamily of CDD/CDA-like deaminases HOK_GEF PF01848.11 KEP61611.1 - 0.053 12.8 0.2 0.11 11.7 0.1 1.6 1 0 0 1 1 1 0 Hok/gef family DUF2088 PF09861.4 KEP61611.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2088) Rab5ip PF07019.7 KEP61616.1 - 1.8e-14 53.5 6.2 2.6e-14 53.1 4.3 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) RCC1 PF00415.13 KEP61617.1 - 1.2e-37 127.9 4.0 1.3e-05 25.2 0.0 11.0 10 1 0 10 10 10 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP61617.1 - 3.1e-22 77.6 44.0 1.6e-07 30.7 0.2 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat PMM PF03332.8 KEP61618.1 - 8.9e-93 309.8 0.0 1e-92 309.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KEP61618.1 - 2.5e-09 37.0 0.0 1.1e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEP61618.1 - 7.3e-08 32.0 0.0 0.00073 18.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.1 KEP61618.1 - 0.012 15.8 0.0 0.74 10.0 0.0 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEP61618.1 - 0.062 13.7 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP61618.1 - 0.11 12.6 0.4 0.42 10.7 0.2 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase KOW PF00467.24 KEP61619.1 - 2.1e-05 24.0 1.3 4e-05 23.1 0.9 1.5 1 0 0 1 1 1 1 KOW motif PIG-H PF10181.4 KEP61621.1 - 2.7e-14 52.5 0.1 4.6e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Fringe PF02434.11 KEP61622.1 - 2.5e-18 66.2 2.0 3.3e-09 36.3 0.0 3.6 3 1 0 3 3 3 2 Fringe-like Galactosyl_T PF01762.16 KEP61622.1 - 0.019 14.5 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Galactosyltransferase DUF2868 PF11067.3 KEP61623.1 - 0.071 12.2 1.8 0.12 11.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Corona_S2 PF01601.11 KEP61623.1 - 8.9 4.2 6.4 14 3.6 4.4 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ribosomal_L22e PF01776.12 KEP61624.1 - 1.6e-43 147.2 1.6 1.9e-43 147.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family FERM_M PF00373.13 KEP61624.1 - 0.096 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 FERM central domain IMCp PF12314.3 KEP61625.1 - 3.5e-07 30.2 15.3 1.9e-06 27.8 2.2 2.4 2 1 0 2 2 2 2 Inner membrane complex protein Pescadillo_N PF06732.6 KEP61627.1 - 3.2e-83 279.2 0.9 7.5e-83 278.0 0.6 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 KEP61627.1 - 2e-07 31.0 0.0 3.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain CENP-T PF15511.1 KEP61627.1 - 4.2 6.5 40.2 3.1 6.9 19.1 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Chorein_N PF12624.2 KEP61629.1 - 1.1e-07 31.4 0.1 1.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter HlyD_2 PF12700.2 KEP61629.1 - 0.012 14.7 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein 2-Hacid_dh_C PF02826.14 KEP61631.1 - 5e-61 204.9 0.1 7.8e-61 204.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEP61631.1 - 2.9e-32 110.9 0.2 4.5e-32 110.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEP61631.1 - 4.9e-08 32.9 0.1 1.3e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 KEP61631.1 - 0.0013 18.1 0.2 0.0064 15.9 0.1 2.2 1 1 0 1 1 1 1 ACT domain IlvN PF07991.7 KEP61631.1 - 0.0074 15.6 0.4 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KEP61631.1 - 0.0076 15.9 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KEP61631.1 - 0.044 13.3 0.5 0.26 10.8 0.0 2.3 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 KEP61631.1 - 0.052 13.9 0.1 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ACT_4 PF13291.1 KEP61631.1 - 0.1 12.9 0.1 0.44 10.9 0.1 2.2 1 1 0 1 1 1 0 ACT domain DUF2642 PF10842.3 KEP61631.1 - 0.13 11.8 0.1 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) RabGAP-TBC PF00566.13 KEP61632.1 - 0.00012 21.6 0.3 0.00018 21.0 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ras PF00071.17 KEP61633.1 - 5.7e-33 113.6 0.1 7.4e-21 74.2 0.0 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEP61633.1 - 1.1e-16 61.3 0.0 2.6e-15 56.9 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein DnaJ PF00226.26 KEP61633.1 - 2.1e-16 59.3 0.0 4.4e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Arf PF00025.16 KEP61633.1 - 9.7e-13 47.7 0.0 2.6e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEP61633.1 - 0.0039 16.6 0.0 0.069 12.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEP61633.1 - 0.045 12.8 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Peptidase_U35_2 PF14550.1 KEP61633.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative phage protease XkdF CBS PF00571.23 KEP61634.1 - 8.7e-12 44.6 0.3 1.7e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain CAP PF00188.21 KEP61636.1 - 3.3e-11 43.7 0.0 4.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase PF00069.20 KEP61637.1 - 9e-17 61.0 0.0 5.6e-08 32.2 0.0 3.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61637.1 - 0.0014 17.7 0.0 0.19 10.8 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Cyclin_N PF00134.18 KEP61638.1 - 0.00043 19.8 0.1 0.098 12.2 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain CTNNBL PF08216.6 KEP61639.1 - 1.4e-29 101.8 2.9 1.4e-29 101.8 2.0 3.2 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KEP61639.1 - 0.0031 17.2 0.8 0.019 14.7 0.0 2.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Nuc_deoxyrib_tr PF05014.10 KEP61639.1 - 0.21 11.4 2.3 0.56 10.0 0.3 2.7 2 1 0 3 3 3 0 Nucleoside 2-deoxyribosyltransferase Peptidase_C37 PF05416.7 KEP61639.1 - 0.3 9.3 9.2 0.45 8.7 6.4 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase HEAT_2 PF13646.1 KEP61639.1 - 0.35 11.1 6.2 0.7 10.2 0.1 3.6 4 0 0 4 4 4 0 HEAT repeats DDHD PF02862.12 KEP61639.1 - 0.97 9.1 10.4 1.5 8.5 5.1 2.3 2 0 0 2 2 2 0 DDHD domain RRM_1 PF00076.17 KEP61642.1 - 2.1e-17 62.5 0.0 3e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP61642.1 - 4.5e-12 45.7 0.0 6.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP61642.1 - 6.3e-10 38.7 0.2 9.1e-10 38.2 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 KEP61642.1 - 1.9e-06 27.5 0.6 1.9e-06 27.5 0.4 1.9 2 0 0 2 2 2 1 WW domain MFS_1 PF07690.11 KEP61643.1 - 4.5e-22 78.2 35.9 1e-13 50.7 8.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pol_alpha_B_N PF08418.5 KEP61643.1 - 2.2 7.7 17.1 7.1 6.0 11.9 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Apt1 PF10351.4 KEP61643.1 - 3 6.5 17.9 5.8 5.6 12.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.20 KEP61644.1 - 4.2e-20 71.9 0.0 2e-16 59.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61644.1 - 1.5e-08 33.9 0.0 2.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP61644.1 - 4.6e-05 22.5 0.0 7.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEP61644.1 - 0.0076 16.0 1.8 0.021 14.5 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEP61644.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHO4 PF01384.15 KEP61646.1 - 5.6e-110 367.0 0.0 1.9e-109 365.2 0.0 1.7 1 1 0 1 1 1 1 Phosphate transporter family Lectin_N PF03954.9 KEP61647.1 - 0.37 10.1 14.6 0.51 9.7 1.1 4.3 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain Bacillus_HBL PF05791.6 KEP61647.1 - 0.44 9.8 16.0 0.13 11.6 2.9 3.5 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Tht1 PF04163.7 KEP61647.1 - 0.59 8.4 0.5 0.96 7.7 0.4 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF948 PF06103.6 KEP61647.1 - 6.3 6.7 9.2 32 4.4 0.1 4.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Streptin-Immun PF11083.3 KEP61648.1 - 0.0038 17.2 10.1 0.0082 16.1 1.1 3.2 1 1 0 2 2 2 1 Lantibiotic streptin immunity protein SlyX PF04102.7 KEP61648.1 - 0.034 14.5 6.5 0.034 14.5 4.5 3.8 1 1 2 3 3 3 0 SlyX FH2 PF02181.18 KEP61648.1 - 0.33 9.7 18.3 0.027 13.3 5.0 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF3584 PF12128.3 KEP61648.1 - 0.41 7.9 25.1 0.014 12.7 7.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Macoilin PF09726.4 KEP61648.1 - 0.48 8.6 23.4 0.61 8.3 16.2 1.0 1 0 0 1 1 1 0 Transmembrane protein AAA_5 PF07728.9 KEP61648.1 - 0.53 10.0 5.3 3 7.5 3.7 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) GAS PF13851.1 KEP61648.1 - 0.84 8.7 27.7 1 8.4 13.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KEP61648.1 - 1 8.5 6.6 0.77 8.8 2.5 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 KEP61648.1 - 1.1 8.5 14.4 0.61 9.4 3.9 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4243 PF14027.1 KEP61648.1 - 1.4 8.2 6.5 0.93 8.8 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4243) DUF342 PF03961.8 KEP61648.1 - 1.4 7.2 20.3 1 7.7 6.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Z1 PF10593.4 KEP61648.1 - 1.7 7.7 11.5 0.87 8.7 3.6 2.1 1 1 0 2 2 2 0 Z1 domain Fib_alpha PF08702.5 KEP61648.1 - 1.8 8.6 23.1 0.066 13.3 5.6 3.0 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 KEP61648.1 - 2 8.2 26.3 4.5 7.1 1.6 3.8 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Transposase_22 PF02994.9 KEP61648.1 - 2.9 6.2 23.0 32 2.8 15.9 2.0 1 1 0 1 1 1 0 L1 transposable element SNARE PF05739.14 KEP61648.1 - 3.3 7.4 11.9 0.26 11.0 0.6 3.5 3 1 0 3 3 3 0 SNARE domain DUF1479 PF07350.7 KEP61648.1 - 3.3 6.1 8.5 2 6.8 4.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1479) IncA PF04156.9 KEP61648.1 - 3.6 7.1 31.9 1.8 8.1 14.4 2.3 1 1 1 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 KEP61648.1 - 4.9 6.9 24.9 1 9.1 3.1 3.6 1 1 3 4 4 4 0 Prefoldin subunit DUF948 PF06103.6 KEP61648.1 - 5.5 6.9 16.5 6.6 6.6 4.3 3.9 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 KEP61648.1 - 6.7 6.5 19.0 1.5 8.6 4.5 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2570 PF10828.3 KEP61648.1 - 8 6.1 20.7 3.6 7.2 10.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2570) Peptidase_S8 PF00082.17 KEP61649.1 - 4.2e-30 104.8 0.0 2.9e-28 98.8 0.0 2.3 1 1 0 1 1 1 1 Subtilase family DUF3429 PF11911.3 KEP61650.1 - 0.23 11.4 8.6 0.35 10.8 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) Macro PF01661.16 KEP61651.1 - 7.7e-31 106.4 0.0 1.4e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Macro domain Mitoc_L55 PF09776.4 KEP61652.1 - 2 8.0 6.5 0.59 9.7 1.4 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L55 TP1 PF02079.11 KEP61653.1 - 0.0094 15.6 0.6 0.0094 15.6 0.4 1.5 2 0 0 2 2 2 1 Nuclear transition protein 1 S1-P1_nuclease PF02265.11 KEP61656.1 - 4e-20 72.5 0.2 6.3e-19 68.5 0.2 2.1 1 1 0 1 1 1 1 S1/P1 Nuclease Radial_spoke_3 PF06098.6 KEP61657.1 - 1.4e-29 103.0 2.9 3.5e-29 101.7 2.0 1.6 1 0 0 1 1 1 1 Radial spoke protein 3 Apolipoprotein PF01442.13 KEP61662.1 - 0.0096 15.4 0.9 0.018 14.5 0.1 1.8 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Nramp PF01566.13 KEP61663.1 - 4.2e-90 302.1 14.2 4.2e-90 302.1 9.8 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein COPI_assoc PF08507.5 KEP61665.1 - 5.7e-17 61.6 4.8 7.4e-17 61.3 3.3 1.1 1 0 0 1 1 1 1 COPI associated protein DUF443 PF04276.7 KEP61665.1 - 0.01 15.3 5.3 0.014 14.8 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF443) Claudin_2 PF13903.1 KEP61665.1 - 0.42 10.2 7.2 0.059 13.0 1.5 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1202 PF06717.6 KEP61666.1 - 0.54 9.4 11.0 1.4 8.1 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Reo_sigmaC PF04582.7 KEP61666.1 - 8.3 5.4 18.8 5.1 6.1 0.8 3.5 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Fumerase PF05681.9 KEP61667.1 - 6.1e-87 291.1 0.0 7.8e-87 290.7 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 KEP61667.1 - 1.2e-77 259.7 0.0 1.6e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus DHODB_Fe-S_bind PF10418.4 KEP61667.1 - 0.023 14.2 1.8 0.072 12.5 1.3 1.9 1 1 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B LSM PF01423.17 KEP61670.1 - 7.8e-17 60.5 1.3 1e-16 60.2 0.9 1.1 1 0 0 1 1 1 1 LSM domain LRR_4 PF12799.2 KEP61670.1 - 0.066 12.8 0.2 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEP61670.1 - 0.077 13.0 0.6 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Leucine Rich Repeat SIR2 PF02146.12 KEP61671.1 - 1.7e-15 57.2 0.0 2.8e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 Sir2 family Kinesin PF00225.18 KEP61673.1 - 1.1e-35 122.9 0.0 7.8e-35 120.1 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Rbsn PF11464.3 KEP61673.1 - 0.87 9.2 3.2 2.2 7.9 2.2 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Nuc_sug_transp PF04142.10 KEP61674.1 - 1.7e-84 282.7 13.7 2.6e-84 282.1 6.5 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 KEP61674.1 - 6.3e-08 31.8 8.0 6.3e-08 31.8 5.5 2.1 2 1 0 2 2 2 1 UAA transporter family EmrE PF13536.1 KEP61674.1 - 2.1e-06 27.8 6.7 2.1e-06 27.8 4.7 3.2 4 1 0 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 KEP61674.1 - 5e-06 26.2 24.4 4.9e-05 23.0 6.6 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KEP61674.1 - 0.0038 17.2 7.5 0.0038 17.2 5.2 3.3 3 1 0 3 3 3 1 EamA-like transporter family RNA_pol_A_bac PF01000.21 KEP61675.1 - 1.1e-28 99.5 0.0 2e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KEP61675.1 - 3e-17 61.4 0.0 3.8e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.1 KEP61675.1 - 0.012 15.8 1.6 0.025 14.8 1.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 KEP61675.1 - 0.039 13.7 1.6 0.08 12.7 1.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 KEP61675.1 - 0.051 13.9 1.5 0.12 12.8 1.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Ribosomal_L32e PF01655.13 KEP61676.1 - 6.8e-47 158.0 0.8 8.6e-47 157.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 LCCL PF03815.14 KEP61677.1 - 9.9e-95 310.7 1.9 1.8e-25 88.7 0.0 4.4 4 0 0 4 4 4 4 LCCL domain SRCR PF00530.13 KEP61677.1 - 5.5e-29 100.4 13.4 4.2e-14 52.6 1.7 2.9 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain PLAT PF01477.18 KEP61677.1 - 4.1e-18 65.8 0.0 7.1e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 PLAT/LH2 domain Laminin_G_3 PF13385.1 KEP61677.1 - 2e-13 50.9 0.0 4.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Rxt3 PF08642.5 KEP61677.1 - 2.5e-09 37.3 0.0 0.0077 16.4 0.0 3.8 3 1 0 3 3 3 2 Histone deacetylation protein Rxt3 SRCR_2 PF15494.1 KEP61677.1 - 5.5e-06 26.5 1.7 0.0077 16.4 0.2 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Pentaxin PF00354.12 KEP61677.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Pentaxin family Mago_nashi PF02792.9 KEP61678.1 - 6.2e-82 272.3 0.6 7e-82 272.2 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 KEP61678.1 - 0.045 13.5 0.2 0.085 12.6 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) DnaJ PF00226.26 KEP61679.1 - 2.8e-16 58.9 0.0 6.2e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain RLL PF10036.4 KEP61679.1 - 0.05 13.0 1.3 0.09 12.2 0.9 1.4 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein zf-C3HC4_3 PF13920.1 KEP61680.1 - 1.4e-16 59.8 12.2 2.8e-16 58.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP61680.1 - 1.9e-07 31.0 13.8 3.8e-07 30.0 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP61680.1 - 8.4e-06 25.5 12.2 1.9e-05 24.3 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-P11 PF03854.9 KEP61680.1 - 0.00011 21.5 7.6 0.00023 20.5 5.3 1.5 1 0 0 1 1 1 1 P-11 zinc finger Prok-RING_4 PF14447.1 KEP61680.1 - 0.0044 16.5 5.9 0.0044 16.5 4.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 KEP61680.1 - 0.0073 16.0 11.7 0.017 14.8 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KEP61680.1 - 2.5 7.7 10.1 5.4 6.6 7.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RCC1_2 PF13540.1 KEP61681.1 - 0.00036 20.0 20.5 1.9 8.1 0.3 6.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat AP2 PF00847.15 KEP61682.1 - 2e-11 43.8 0.7 3.6e-11 43.0 0.5 1.4 1 0 0 1 1 1 1 AP2 domain Neuromodulin PF06614.6 KEP61682.1 - 0.88 9.4 11.5 0.061 13.2 3.7 2.3 2 0 0 2 2 2 0 Neuromodulin CSD PF00313.17 KEP61683.1 - 1.5e-25 88.7 0.4 2.1e-25 88.2 0.3 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 KEP61683.1 - 0.0019 17.6 0.1 0.0019 17.6 0.1 2.0 2 1 0 2 2 2 1 Ribonuclease B OB domain S1 PF00575.18 KEP61683.1 - 0.084 12.9 0.1 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain TRM PF02005.11 KEP61684.1 - 6.4e-104 347.8 0.1 2.4e-75 253.8 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KEP61684.1 - 9.5e-05 22.4 0.2 0.00058 19.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEP61684.1 - 0.0082 15.2 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KEP61684.1 - 0.021 15.4 0.0 8.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.11 KEP61684.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Peptidase_C1 PF00112.18 KEP61685.1 - 5.3e-39 134.3 4.7 5.9e-39 134.2 1.0 2.2 2 0 0 2 2 2 1 Papain family cysteine protease CathepsinC_exc PF08773.6 KEP61685.1 - 6.1e-11 42.5 0.0 1.4e-07 31.6 0.0 3.1 3 0 0 3 3 3 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 KEP61685.1 - 0.17 10.3 2.0 0.64 8.4 0.6 2.2 3 0 0 3 3 3 0 Peptidase C1-like family SAM_1 PF00536.25 KEP61686.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Vma12 PF11712.3 KEP61687.1 - 9.2e-10 38.3 0.1 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-rbx1 PF12678.2 KEP61688.1 - 3.7e-23 81.4 5.8 4.8e-23 81.0 4.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEP61688.1 - 8.5e-23 80.0 5.9 1.1e-22 79.6 4.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KEP61688.1 - 1.1e-07 31.5 11.7 3.1e-07 30.1 8.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEP61688.1 - 3.6e-06 26.5 8.6 2.5e-05 23.8 6.0 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEP61688.1 - 3.4e-05 23.4 5.2 7.2e-05 22.3 3.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP61688.1 - 0.00011 22.1 6.8 0.00064 19.6 4.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP61688.1 - 0.00044 19.8 8.7 0.0025 17.4 6.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KEP61688.1 - 0.0018 18.2 6.2 0.0029 17.5 4.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KEP61688.1 - 0.01 15.6 2.0 0.01 15.6 1.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.24 KEP61688.1 - 1.4 8.6 10.6 53 3.6 7.3 2.3 1 1 0 1 1 1 0 PHD-finger RINGv PF12906.2 KEP61688.1 - 1.6 8.8 9.4 6.3 6.9 6.5 2.0 1 1 0 1 1 1 0 RING-variant domain zf-HIT PF04438.11 KEP61688.1 - 1.6 8.4 9.6 0.28 10.8 3.1 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-HC5HC2H PF13771.1 KEP61688.1 - 2.9 8.0 8.2 9.5 6.4 5.7 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_4 PF14570.1 KEP61688.1 - 6 6.5 9.9 25 4.5 6.8 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Synaptobrevin PF00957.16 KEP61689.1 - 0.026 14.1 0.6 1 9.0 0.0 3.0 3 0 0 3 3 3 0 Synaptobrevin APG17 PF04108.7 KEP61689.1 - 0.068 11.9 0.5 0.14 10.9 0.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 Pkinase PF00069.20 KEP61690.1 - 5.8e-71 238.6 0.0 7.2e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61690.1 - 4.7e-34 117.6 0.0 6.2e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KEP61690.1 - 1.5e-05 25.3 0.0 0.00013 22.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KEP61690.1 - 0.00021 20.3 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_4 PF12799.2 KEP61691.1 - 6.2e-40 134.2 33.7 5.2e-09 35.5 1.2 7.4 4 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP61691.1 - 7.8e-33 112.0 41.5 9.8e-11 41.2 2.1 5.3 2 1 4 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 KEP61691.1 - 3.5e-19 65.8 22.3 0.0056 16.5 0.0 11.0 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.1 KEP61691.1 - 4.3e-17 60.2 15.9 0.0074 16.2 0.0 11.1 7 1 4 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 KEP61691.1 - 1.1e-16 60.8 9.3 8.4e-06 25.4 1.3 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 KEP61691.1 - 8.2e-12 43.2 24.9 0.16 12.2 0.0 11.4 10 2 2 12 12 12 2 Leucine rich repeat LRR_5 PF13306.1 KEP61691.1 - 0.11 12.2 0.6 0.73 9.5 0.0 2.7 2 1 0 3 3 3 0 Leucine rich repeats (6 copies) LRR_2 PF07723.8 KEP61691.1 - 0.72 10.4 7.1 99 3.6 0.0 5.7 7 0 0 7 7 7 0 Leucine Rich Repeat GCV_T PF01571.16 KEP61692.1 - 3.1e-08 33.2 0.0 0.00046 19.6 0.0 2.7 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain Kei1 PF08552.6 KEP61693.1 - 0.75 9.4 1.0 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 NARP1 PF12569.3 KEP61693.1 - 1.8 7.1 7.0 2.8 6.5 4.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RAP1 PF07218.6 KEP61693.1 - 5.7 4.9 8.4 12 3.8 5.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cyclin PF08613.6 KEP61694.1 - 9.3e-33 113.7 0.5 3e-32 112.0 0.3 1.9 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEP61694.1 - 4.1e-10 39.3 0.3 6.9e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Tom37_C PF11801.3 KEP61694.1 - 1.4 8.8 5.5 0.13 12.0 0.4 1.8 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF1768 PF08719.6 KEP61696.1 - 8.2e-17 61.3 0.0 1.7e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.17 KEP61696.1 - 1.3e-11 43.9 0.0 1.1e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 KEP61696.1 - 2.1e-11 43.7 0.0 5.4e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 FHA domain RRM_6 PF14259.1 KEP61696.1 - 4.4e-11 42.6 0.0 9e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP61696.1 - 1.2e-08 34.6 0.0 4.9e-08 32.7 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AP2 PF00847.15 KEP61698.1 - 3.1e-05 24.0 0.5 6.4e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 AP2 domain NAD_binding_10 PF13460.1 KEP61702.1 - 3.8e-19 69.4 0.0 1.7e-14 54.2 0.0 3.0 3 0 0 3 3 3 2 NADH(P)-binding KR PF08659.5 KEP61702.1 - 0.04 13.5 1.2 0.084 12.5 0.1 2.1 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.14 KEP61702.1 - 0.23 10.1 0.0 2.5 6.7 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family LCE PF14672.1 KEP61704.1 - 0.056 13.9 2.6 0.13 12.8 1.8 1.5 1 0 0 1 1 1 0 Late cornified envelope EGF_CA PF07645.10 KEP61705.1 - 1e-211 684.7 546.7 6.2e-11 42.0 6.3 33.3 33 1 1 34 34 34 29 Calcium-binding EGF domain EGF_3 PF12947.2 KEP61705.1 - 9.5e-169 547.0 509.8 2.1e-11 43.5 6.8 33.0 30 2 2 32 32 32 30 EGF domain cEGF PF12662.2 KEP61705.1 - 1.3e-141 459.5 324.2 6.8e-10 38.4 3.5 32.5 32 0 0 32 32 32 28 Complement Clr-like EGF-like EGF PF00008.22 KEP61705.1 - 1.3e-85 280.7 431.0 1.8e-05 24.5 6.4 33.2 31 2 0 31 31 31 28 EGF-like domain FXa_inhibition PF14670.1 KEP61705.1 - 3e-46 155.2 495.0 0.00011 22.1 6.7 32.8 29 3 3 32 32 32 25 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 KEP61705.1 - 1.9e-34 117.0 376.9 4.1e-06 26.4 1.5 32.2 32 0 0 32 32 32 23 MSP1 EGF domain 1 hEGF PF12661.2 KEP61705.1 - 7.1e-12 44.5 186.0 0.081 13.0 1.3 31.1 31 0 0 31 31 31 12 Human growth factor-like EGF SR-25 PF10500.4 KEP61707.1 - 0.12 11.7 2.5 0.23 10.9 1.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1183 PF06682.7 KEP61707.1 - 0.18 11.3 5.2 0.094 12.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) CPSF_A PF03178.10 KEP61708.1 - 2.3e-20 72.9 0.0 7.5e-11 41.6 0.0 3.5 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 KEP61708.1 - 9.7e-16 56.9 0.0 1.6e-10 39.7 0.0 2.8 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term hSac2 PF12456.3 KEP61708.1 - 0.0011 18.3 0.1 0.0024 17.2 0.1 1.5 1 0 0 1 1 1 1 Inositol phosphatase RAP1 PF07218.6 KEP61708.1 - 0.79 7.7 11.0 1.2 7.1 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.6 KEP61708.1 - 4.1 5.1 5.8 6.9 4.4 4.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.4 KEP61708.1 - 5.1 5.8 4.3 0.77 8.5 0.0 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ion_trans PF00520.26 KEP61709.1 - 3.1e-13 49.4 16.9 4.9e-13 48.7 11.7 1.3 1 0 0 1 1 1 1 Ion transport protein TPT PF03151.11 KEP61711.1 - 3.1e-15 56.1 13.4 5.2e-15 55.4 2.6 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KEP61711.1 - 0.001 18.1 9.2 0.004 16.1 6.4 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEP61711.1 - 0.012 15.6 24.5 0.016 15.2 1.1 3.4 3 1 0 4 4 4 0 EamA-like transporter family Kei1 PF08552.6 KEP61713.1 - 7.8 6.1 5.3 5.4 6.6 0.0 3.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 VCX_VCY PF15231.1 KEP61714.1 - 1.6 9.1 9.8 1.7 9.0 6.8 1.0 1 0 0 1 1 1 0 Variable charge X/Y family DUF1342 PF07072.6 KEP61715.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) RAP PF08373.5 KEP61716.1 - 0.0003 20.5 0.0 0.00064 19.4 0.0 1.5 1 0 0 1 1 1 1 RAP domain Dynamin_M PF01031.15 KEP61718.1 - 1.8e-104 348.6 0.0 2.8e-104 348.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KEP61718.1 - 7.2e-52 175.5 0.0 1.2e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KEP61718.1 - 2.6e-31 107.3 1.7 4.7e-31 106.5 0.4 2.0 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEP61718.1 - 4.4e-05 23.4 0.0 0.00012 21.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEP61718.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 KEP61718.1 - 0.037 13.9 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEP61718.1 - 0.065 13.2 1.3 0.38 10.7 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain FeoB_N PF02421.13 KEP61718.1 - 0.15 11.3 0.1 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.17 KEP61719.1 - 1.4e-58 196.8 0.1 1.6e-58 196.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP61719.1 - 1.3e-18 67.6 0.0 2.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP61719.1 - 2.2e-15 56.3 0.0 2.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEP61719.1 - 0.00069 19.0 0.0 0.002 17.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEP61719.1 - 0.00089 18.4 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEP61719.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase S6PP_C PF08472.5 KEP61719.1 - 0.098 12.2 0.0 7.5 6.1 0.0 2.5 2 1 1 3 3 3 0 Sucrose-6-phosphate phosphohydrolase C-terminal ETF PF01012.16 KEP61720.1 - 1.8e-33 115.5 0.2 2.8e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPR_11 PF13414.1 KEP61721.1 - 3.8e-10 39.2 2.7 0.00013 21.5 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KEP61721.1 - 5.3e-10 38.4 6.7 4.1e-05 23.1 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEP61721.1 - 1.2e-07 31.9 1.2 0.013 15.7 0.0 3.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEP61721.1 - 2.6e-07 30.6 16.0 0.0016 18.9 0.0 5.6 4 2 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP61721.1 - 6.6e-07 29.0 4.3 0.33 11.2 0.0 5.8 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEP61721.1 - 5.8e-06 25.6 1.4 0.0043 16.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP61721.1 - 2.2e-05 25.0 3.8 0.0033 18.0 0.1 5.3 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEP61721.1 - 0.00016 21.1 0.0 0.04 13.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEP61721.1 - 0.00041 20.1 12.7 0.033 14.0 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEP61721.1 - 0.0013 19.0 0.2 1.2 9.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP61721.1 - 0.013 15.2 4.7 5.6 7.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP61721.1 - 0.067 13.1 10.7 2.2 8.2 0.0 4.5 2 1 2 5 5 5 0 Tetratricopeptide repeat MIP-T3 PF10243.4 KEP61722.1 - 3.8e-05 22.3 40.2 3.8e-05 22.3 27.8 6.6 7 0 0 7 7 7 2 Microtubule-binding protein MIP-T3 NYD-SP28_assoc PF14775.1 KEP61723.1 - 3.6e-14 52.1 0.1 3.6e-14 52.1 0.0 2.7 3 1 0 3 3 3 1 Sperm tail C-terminal domain Glyco_transf_90 PF05686.7 KEP61724.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 Podoplanin PF05808.6 KEP61724.1 - 6.2 6.3 8.8 10 5.6 6.2 1.3 1 1 0 1 1 1 0 Podoplanin DUF4269 PF14091.1 KEP61726.1 - 6.8 6.6 0.0 12 5.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) DEAD PF00270.24 KEP61727.1 - 1.1e-43 148.7 0.4 1.1e-43 148.7 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP61727.1 - 9.1e-27 92.7 0.0 2.8e-26 91.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP61727.1 - 0.0073 16.1 0.0 0.048 13.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 KEP61727.1 - 0.011 15.3 0.1 0.057 13.0 0.0 2.3 2 1 0 2 2 2 0 Helicase Helicase_C_4 PF13871.1 KEP61727.1 - 0.05 13.0 0.5 1.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Helicase_C-like AAA_22 PF13401.1 KEP61727.1 - 0.66 10.1 4.0 2.4 8.3 0.7 3.0 2 1 0 2 2 2 0 AAA domain VMA21 PF09446.5 KEP61728.1 - 3.2e-05 23.7 8.3 6.4e-05 22.7 5.8 1.5 1 1 0 1 1 1 1 VMA21-like domain Ni_hydr_CYTB PF01292.15 KEP61728.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TraQ PF09679.5 KEP61729.1 - 0.0085 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) YdjC PF04794.7 KEP61729.1 - 0.03 13.7 0.1 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 YdjC-like protein Rubrerythrin PF02915.12 KEP61729.1 - 0.054 13.8 1.5 0.066 13.5 0.2 1.7 2 0 0 2 2 2 0 Rubrerythrin AAA_24 PF13479.1 KEP61729.1 - 0.067 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain SNARE_assoc PF09335.6 KEP61731.1 - 6.5e-07 29.5 2.9 6.5e-07 29.5 2.0 2.9 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF4014 PF13198.1 KEP61731.1 - 0.11 12.8 1.7 0.25 11.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) DUF1749 PF08538.5 KEP61732.1 - 3.6e-57 193.5 0.0 4.5e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KEP61732.1 - 1.5e-15 57.7 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP61732.1 - 2.7e-10 40.1 0.0 5.4e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 KEP61732.1 - 5.1e-05 22.7 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 KEP61732.1 - 0.00023 20.3 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.8 KEP61732.1 - 0.00063 19.2 0.0 0.0025 17.2 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 KEP61732.1 - 0.0022 17.3 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2305 PF10230.4 KEP61732.1 - 0.0022 17.4 0.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) VirJ PF06057.6 KEP61732.1 - 0.0054 16.5 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.15 KEP61732.1 - 0.03 13.8 0.0 2 7.8 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEP61732.1 - 0.072 12.3 0.0 0.68 9.1 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family LCAT PF02450.10 KEP61732.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Peptidase_M24 PF00557.19 KEP61733.1 - 6.2e-27 94.5 0.4 8.9e-27 94.0 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Glutaredoxin PF00462.19 KEP61734.1 - 1.5e-16 60.0 0.1 2.1e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KEP61734.1 - 9.1e-05 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 KEP61734.1 - 0.0001 21.8 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEP61734.1 - 0.00017 21.7 0.5 0.0005 20.2 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 KEP61734.1 - 0.00023 21.1 0.4 0.05 13.6 0.3 2.1 1 1 1 2 2 2 2 Thioredoxin DUF836 PF05768.9 KEP61734.1 - 0.001 19.2 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 KEP61734.1 - 0.0041 16.6 1.4 0.19 11.2 0.1 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain OTT_1508_deam PF14441.1 KEP61734.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 0 OTT_1508-like deaminase GST_N_3 PF13417.1 KEP61734.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Redoxin PF08534.5 KEP61734.1 - 0.015 14.8 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Redoxin DiS_P_DiS PF06750.8 KEP61734.1 - 0.02 14.6 0.1 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain FANCL_C PF11793.3 KEP61734.1 - 0.032 14.1 0.0 0.074 13.0 0.0 1.5 2 0 0 2 2 2 0 FANCL C-terminal domain YyzF PF14116.1 KEP61734.1 - 0.041 13.8 1.2 0.85 9.6 0.1 2.2 2 0 0 2 2 2 0 YyzF-like protein TraF PF13728.1 KEP61734.1 - 0.078 12.4 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.16 KEP61734.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.1 KEP61734.1 - 0.11 12.6 0.1 1 9.5 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Apo-CIII PF05778.7 KEP61734.1 - 0.11 11.8 0.6 0.29 10.5 0.0 1.9 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) DUF4405 PF14358.1 KEP61736.1 - 0.24 11.5 0.6 0.5 10.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) cwf18 PF08315.7 KEP61737.1 - 2.9e-25 89.2 0.2 4.7e-25 88.5 0.1 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SCP1201-deam PF14428.1 KEP61737.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 SCP1.201-like deaminase PA14 PF07691.7 KEP61738.1 - 3.5e-30 104.5 0.0 1.2e-28 99.5 0.0 2.3 2 0 0 2 2 2 2 PA14 domain Adenylsucc_synt PF00709.16 KEP61739.1 - 5.4e-154 512.9 0.0 6.1e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase m04gp34like PF12216.3 KEP61741.1 - 0.014 14.7 0.6 0.014 14.7 0.4 1.7 2 0 0 2 2 2 0 Immune evasion protein DUF2694 PF10904.3 KEP61741.1 - 0.028 14.4 1.9 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2694) GRA6 PF05084.8 KEP61741.1 - 0.03 13.8 1.6 0.044 13.3 1.1 1.3 1 1 0 1 1 1 0 Granule antigen protein (GRA6) Shisa PF13908.1 KEP61741.1 - 8.8 6.4 7.9 3.5 7.7 2.7 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator ATP-sulfurylase PF01747.12 KEP61742.1 - 9.9e-75 250.5 0.0 1.3e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KEP61742.1 - 2.6e-57 192.8 0.0 4.6e-57 192.0 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KEP61742.1 - 1.5e-26 92.7 0.0 1.1e-24 86.6 0.0 2.3 1 1 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KEP61742.1 - 6.5e-09 35.7 0.0 1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEP61742.1 - 3.1e-05 23.3 0.0 5.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KEP61742.1 - 5.3e-05 24.0 0.0 0.00012 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEP61742.1 - 9.3e-05 22.7 0.0 0.00024 21.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEP61742.1 - 0.0023 17.9 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEP61742.1 - 0.052 13.0 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEP61742.1 - 0.074 13.3 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KEP61742.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 KEP61742.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 KEP61742.1 - 0.18 10.8 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 KEP61742.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AP2 PF00847.15 KEP61743.1 - 3.5e-24 84.6 5.5 9.4e-09 35.2 0.3 3.6 3 0 0 3 3 3 3 AP2 domain DUF4110 PF13422.1 KEP61743.1 - 5 7.0 6.6 2.1 8.2 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) ACDC PF14733.1 KEP61744.1 - 5.9e-26 90.4 0.0 1e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 KEP61744.1 - 1e-05 25.5 4.5 2e-05 24.6 3.1 1.5 1 0 0 1 1 1 1 AP2 domain AAA_2 PF07724.9 KEP61745.1 - 1.7e-41 142.0 0.8 1.2e-39 135.9 0.3 3.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEP61745.1 - 1.2e-25 90.1 0.1 9.7e-13 48.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEP61745.1 - 2.4e-17 62.6 0.0 6e-16 58.1 0.0 3.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KEP61745.1 - 1e-15 57.6 0.1 1.1e-09 38.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEP61745.1 - 1.8e-15 57.4 4.4 1.5e-05 25.0 0.1 4.8 3 1 1 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 KEP61745.1 - 3e-11 43.5 4.0 0.00023 21.3 0.0 4.6 3 1 1 4 4 4 2 AAA domain Clp_N PF02861.15 KEP61745.1 - 8.3e-09 35.2 0.0 0.0089 15.9 0.0 3.1 2 0 0 2 2 2 2 Clp amino terminal domain IstB_IS21 PF01695.12 KEP61745.1 - 7.5e-08 31.9 0.0 0.0057 16.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 KEP61745.1 - 1.7e-07 30.8 0.6 9.1e-06 25.2 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KEP61745.1 - 4.4e-07 29.8 0.1 0.1 12.4 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEP61745.1 - 4.5e-07 30.7 1.3 0.009 16.8 0.0 3.5 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KEP61745.1 - 1.1e-06 28.5 7.0 0.14 11.8 0.2 4.9 3 2 0 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 KEP61745.1 - 8.3e-06 26.1 4.6 0.051 13.8 0.0 4.0 3 1 1 4 4 2 2 AAA domain NACHT PF05729.7 KEP61745.1 - 1.4e-05 24.7 0.1 0.086 12.4 0.0 3.2 3 1 0 3 3 2 2 NACHT domain RNA_helicase PF00910.17 KEP61745.1 - 1.5e-05 25.1 0.1 0.2 11.8 0.0 3.1 2 1 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 KEP61745.1 - 1.7e-05 24.0 1.3 0.0074 15.3 0.0 3.9 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus TniB PF05621.6 KEP61745.1 - 3.4e-05 22.7 0.0 0.00026 19.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.1 KEP61745.1 - 5.5e-05 23.0 0.0 0.062 13.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEP61745.1 - 7.3e-05 22.0 1.3 0.42 9.7 0.1 3.6 2 2 0 2 2 2 2 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KEP61745.1 - 0.00016 21.5 3.4 0.93 9.2 0.0 4.4 4 1 1 5 5 4 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KEP61745.1 - 0.00032 20.1 0.8 0.64 9.3 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_19 PF13245.1 KEP61745.1 - 0.00036 20.2 0.0 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KEP61745.1 - 0.00047 19.8 1.1 0.0078 15.8 0.4 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEP61745.1 - 0.00047 19.3 3.8 0.011 14.8 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin T2SE PF00437.15 KEP61745.1 - 0.0015 17.4 0.0 0.0067 15.3 0.0 2.0 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 KEP61745.1 - 0.003 17.0 1.6 0.81 9.0 0.0 3.7 4 1 0 4 4 4 1 AAA-like domain DUF258 PF03193.11 KEP61745.1 - 0.0035 16.5 0.1 1.8 7.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF815 PF05673.8 KEP61745.1 - 0.004 16.1 0.1 0.25 10.2 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 KEP61745.1 - 0.0061 16.5 2.7 2.2 8.2 0.0 3.4 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 KEP61745.1 - 0.0069 16.0 0.0 3.6 7.2 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KEP61745.1 - 0.011 15.4 0.3 5.5 6.6 0.0 3.9 4 0 0 4 4 4 0 NTPase DNA_pol3_delta2 PF13177.1 KEP61745.1 - 0.014 15.0 0.5 0.25 10.9 0.0 3.0 2 1 0 2 2 1 0 DNA polymerase III, delta subunit AAA_3 PF07726.6 KEP61745.1 - 0.015 14.8 1.4 19 4.9 0.0 4.2 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KEP61745.1 - 0.018 14.6 0.1 4.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KEP61745.1 - 0.033 14.5 8.9 0.55 10.5 0.0 4.3 2 2 0 2 2 1 0 ABC transporter MMR_HSR1 PF01926.18 KEP61745.1 - 0.033 14.1 0.0 9.4 6.2 0.0 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KEP61745.1 - 0.042 13.3 0.6 6.4 6.3 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain GYF PF02213.11 KEP61745.1 - 0.21 11.1 0.0 0.51 9.9 0.0 1.6 1 0 0 1 1 1 0 GYF domain DUF4238 PF14022.1 KEP61745.1 - 3.9 6.6 8.8 38 3.4 4.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4238) NUDIX PF00293.23 KEP61746.1 - 5.4e-18 64.9 0.1 1.2e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4391 PF14335.1 KEP61747.1 - 0.054 12.8 0.1 0.076 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) MdcG PF10620.4 KEP61748.1 - 0.068 12.7 0.3 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG DUF3716 PF12511.3 KEP61748.1 - 0.75 9.4 3.7 1.4 8.5 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) RAP1 PF07218.6 KEP61750.1 - 0.037 12.1 8.8 0.081 11.0 6.1 1.7 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4613 PF15390.1 KEP61750.1 - 1 7.4 17.6 2.5 6.1 12.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Pheromone PF08015.6 KEP61750.1 - 3 8.7 10.3 17 6.3 7.1 2.3 1 0 0 1 1 1 0 Fungal mating-type pheromone PP2C PF00481.16 KEP61754.1 - 6.3e-21 74.9 0.0 3.3e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C gpUL132 PF11359.3 KEP61757.1 - 0.00076 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycoprotein UL132 Ctr PF04145.10 KEP61758.1 - 0.69 9.9 0.2 9 6.3 0.0 2.9 2 0 0 2 2 2 0 Ctr copper transporter family Isochorismatase PF00857.15 KEP61759.1 - 1.8e-20 73.6 0.1 4.7e-16 59.2 0.1 2.4 2 0 0 2 2 2 2 Isochorismatase family CTP_transf_1 PF01148.15 KEP61760.1 - 3.7e-67 226.7 7.0 8.9e-67 225.4 4.9 1.6 1 1 0 1 1 1 1 Cytidylyltransferase family DUF2427 PF10348.4 KEP61760.1 - 8.1 6.0 8.4 1.3 8.6 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) ADK PF00406.17 KEP61761.1 - 6.7e-27 94.2 0.0 1e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KEP61761.1 - 1.3e-12 48.1 0.0 2.9e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEP61761.1 - 8e-10 39.5 0.0 1.4e-09 38.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP61761.1 - 3.3e-09 36.7 0.1 1.6e-08 34.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEP61761.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEP61761.1 - 0.0044 16.2 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DER1 PF04511.10 KEP61763.1 - 1.4e-23 83.4 0.0 1.9e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Der1-like family TFIIF_beta PF02270.10 KEP61764.1 - 4.4e-09 36.5 0.3 7.8e-06 25.8 0.1 2.9 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit SAG PF04092.8 KEP61765.1 - 3.4e-18 66.2 14.9 9.3e-11 42.1 7.5 2.1 2 0 0 2 2 2 2 SRS domain G8 PF10162.4 KEP61765.1 - 0.046 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 G8 domain ATP-synt_D PF01813.12 KEP61766.1 - 3.6e-60 202.9 0.8 4.2e-60 202.6 0.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit D Sorting_nexin PF03700.8 KEP61766.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain DUF2514 PF10721.4 KEP61766.1 - 2.7 7.6 9.0 0.3 10.7 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) HMG_box PF00505.14 KEP61768.1 - 2.4e-08 34.1 12.1 1.5e-07 31.6 1.4 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KEP61768.1 - 4.8e-05 23.6 4.9 0.00062 20.0 1.4 3.4 3 0 0 3 3 3 1 HMG-box domain SET PF00856.23 KEP61768.1 - 0.0048 17.2 0.0 0.0048 17.2 0.0 4.7 2 2 1 3 3 3 1 SET domain Kinase-like PF14531.1 KEP61769.1 - 2.4e-18 66.1 0.0 1.3e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.20 KEP61769.1 - 4.5e-17 62.0 0.0 8.6e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KEP61769.1 - 7.6e-05 21.8 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KEP61769.1 - 0.00036 19.6 0.0 0.00073 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Lactamase_B PF00753.22 KEP61772.1 - 5.2e-26 91.5 0.5 6.6e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEP61772.1 - 0.00068 19.2 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Dsh_C PF12316.3 KEP61773.1 - 0.017 15.2 6.6 0.022 14.8 4.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Aldo_ket_red PF00248.16 KEP61774.1 - 2.3e-37 128.3 0.0 3.2e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family PP2C PF00481.16 KEP61778.1 - 3.3e-47 161.0 0.0 4.7e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEP61778.1 - 5.4e-06 25.9 0.1 1.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SR-25 PF10500.4 KEP61778.1 - 0.24 10.8 7.0 1 8.7 0.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein VPS9 PF02204.13 KEP61779.1 - 3.8e-05 23.6 0.0 0.0001 22.2 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1042 PF06294.6 KEP61780.1 - 0.0035 16.9 0.0 0.0081 15.7 0.0 1.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1042) Gcd10p PF04189.8 KEP61782.1 - 1.8e-46 158.6 0.0 2.4e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family zf-RING_2 PF13639.1 KEP61784.1 - 1.9e-13 49.9 6.5 1.9e-13 49.9 4.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEP61784.1 - 3.1e-08 33.1 4.0 3.1e-08 33.1 2.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP61784.1 - 4.5e-08 33.0 2.6 1.1e-07 31.8 1.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEP61784.1 - 5.4e-08 32.7 5.6 5.4e-08 32.7 3.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP61784.1 - 5.3e-07 29.2 2.8 1.2e-06 28.1 1.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEP61784.1 - 2.5e-06 27.2 1.0 5.7e-06 26.0 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KEP61784.1 - 2.9e-05 24.0 4.7 5.7e-05 23.0 3.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 KEP61784.1 - 7.3e-05 22.2 5.0 0.0002 20.8 3.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KEP61784.1 - 0.00015 21.6 4.8 0.00079 19.3 3.3 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 KEP61784.1 - 0.00029 20.4 5.0 0.00029 20.4 3.5 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 KEP61784.1 - 0.043 13.3 5.1 0.067 12.6 0.4 2.4 1 1 1 2 2 2 0 P-11 zinc finger Rad50_zn_hook PF04423.9 KEP61784.1 - 0.067 12.6 0.4 2 7.9 0.0 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif Baculo_RING PF05883.6 KEP61784.1 - 0.11 12.3 0.6 0.19 11.5 0.4 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Prok-RING_1 PF14446.1 KEP61784.1 - 0.22 11.2 4.6 0.18 11.5 0.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RNase_HII PF01351.13 KEP61785.1 - 1e-35 123.2 2.9 4e-23 82.1 0.2 3.3 2 1 1 3 3 3 3 Ribonuclease HII Prog_receptor PF02161.10 KEP61785.1 - 0.07 11.9 2.5 0.099 11.4 1.7 1.2 1 0 0 1 1 1 0 Progesterone receptor DUF2201_N PF13203.1 KEP61785.1 - 0.31 10.1 4.1 0.51 9.4 2.9 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 KEP61785.1 - 0.81 7.6 6.9 1.2 7.0 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Aminotran_4 PF01063.14 KEP61786.1 - 1.9e-13 50.4 0.1 4.6e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class IV Pox_Ag35 PF03286.9 KEP61786.1 - 0.0085 15.6 4.6 0.02 14.4 3.2 1.6 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Cytomega_UL84 PF06284.6 KEP61786.1 - 0.24 9.7 1.6 0.36 9.1 1.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Ycf1 PF05758.7 KEP61786.1 - 0.33 8.6 0.7 0.52 7.9 0.5 1.3 1 0 0 1 1 1 0 Ycf1 PBP_sp32 PF07222.7 KEP61786.1 - 2.8 7.0 7.6 8.2 5.5 5.3 1.8 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SNO PF01174.14 KEP61787.1 - 5.2e-42 143.5 0.0 2.6e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KEP61787.1 - 1.6e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 KEP61787.1 - 0.00011 21.7 0.0 0.0006 19.2 0.0 2.0 2 0 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 KEP61787.1 - 0.00021 20.6 0.1 0.0011 18.2 0.0 1.9 2 0 0 2 2 2 1 Putative amidotransferase GATase_5 PF13507.1 KEP61787.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KEP61787.1 - 0.013 14.9 0.0 0.096 12.1 0.0 2.0 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEP61787.1 - 0.014 14.8 0.0 0.056 12.8 0.0 2.1 1 1 0 1 1 1 0 Peptidase C26 WD40 PF00400.27 KEP61788.1 - 6e-20 70.3 15.3 1.8e-07 30.7 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF883 PF05957.8 KEP61790.1 - 0.0081 16.5 1.6 0.026 14.9 1.1 1.8 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Pardaxin PF07425.6 KEP61790.1 - 0.21 11.0 2.7 0.14 11.6 0.2 1.9 2 0 0 2 2 2 0 Pardaxin Pkinase PF00069.20 KEP61791.1 - 2.7e-68 229.9 0.0 3.6e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61791.1 - 1.1e-31 109.9 0.0 2.2e-31 108.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP61791.1 - 0.0014 17.6 0.0 0.0027 16.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KEP61791.1 - 0.036 12.8 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3712 PF12505.3 KEP61792.1 - 1.9e-49 166.8 0.1 2.1e-16 60.0 0.0 9.5 9 0 0 9 9 9 4 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KEP61792.1 - 2e-11 44.1 1.0 5.9 7.3 0.0 8.6 8 0 0 8 8 8 5 Late embryogenesis abundant protein Na_Ala_symp PF01235.12 KEP61792.1 - 0.52 8.8 0.2 0.89 8.0 0.2 1.2 1 0 0 1 1 1 0 Sodium:alanine symporter family DUF4014 PF13198.1 KEP61792.1 - 3.4 8.1 1.9 6.5 7.2 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) Pkinase PF00069.20 KEP61793.1 - 1.6e-41 142.2 0.0 2e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61793.1 - 1.2e-17 63.9 0.0 1.6e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP61793.1 - 5.8e-06 25.4 0.0 9.7e-06 24.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEP61793.1 - 0.082 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KEP61793.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hist_deacetyl PF00850.14 KEP61794.1 - 4.7e-79 265.8 0.1 9.6e-76 255.0 0.7 3.6 2 2 0 2 2 2 2 Histone deacetylase domain IPK PF03770.11 KEP61794.1 - 9.1e-35 120.0 0.0 1.9e-34 119.0 0.0 1.6 1 1 0 1 1 1 1 Inositol polyphosphate kinase DUF1343 PF07075.6 KEP61794.1 - 1.2 7.9 0.1 1.9 7.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) PFK PF00365.15 KEP61795.1 - 6.6e-24 84.3 0.0 4.4e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase DUF1180 PF06679.7 KEP61795.1 - 0.43 10.4 1.7 3.3 7.5 1.2 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NTP_transf_2 PF01909.18 KEP61797.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 KEP61797.1 - 0.027 14.4 0.3 0.083 12.8 0.1 2.0 2 0 0 2 2 2 0 Cid1 family poly A polymerase DUF605 PF04652.11 KEP61798.1 - 0.024 14.0 27.6 0.031 13.6 19.1 1.2 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 KEP61798.1 - 9.4 4.5 8.9 19 3.5 6.2 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 Zip PF02535.17 KEP61800.1 - 0.021 13.8 10.8 0.032 13.2 7.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ELMO_CED12 PF04727.8 KEP61801.1 - 2e-35 121.8 0.3 3.1e-35 121.2 0.2 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family Pkinase PF00069.20 KEP61802.1 - 1.9e-18 66.5 0.0 1.4e-16 60.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61802.1 - 1.4e-05 24.3 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP61802.1 - 0.0027 16.7 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF4283 PF14111.1 KEP61804.1 - 0.22 10.5 0.0 0.43 9.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) EcsC PF12787.2 KEP61804.1 - 1 8.6 3.4 1.6 8.1 2.3 1.2 1 0 0 1 1 1 0 EcsC protein family IncA PF04156.9 KEP61804.1 - 1.1 8.8 7.9 2.5 7.6 5.5 1.5 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.8 KEP61804.1 - 3.6 6.5 5.4 5.1 6.0 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein E1-E2_ATPase PF00122.15 KEP61805.1 - 8.7e-47 159.0 0.5 8.7e-47 159.0 0.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KEP61805.1 - 1.5e-27 97.4 0.2 1.3e-22 81.3 0.0 3.7 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEP61805.1 - 1.1e-18 67.0 0.2 1.4e-11 44.3 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 KEP61805.1 - 3.3e-11 43.7 0.0 2.5e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEP61805.1 - 0.0052 16.4 0.1 0.02 14.4 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GDH_N PF12466.3 KEP61806.1 - 0.018 15.0 0.3 1.2 9.2 0.1 2.5 2 1 1 3 3 3 0 Glutamate dehydrogenase N terminal ETRAMP PF09716.5 KEP61807.1 - 0.0044 16.9 2.6 0.93 9.4 0.6 3.0 3 0 0 3 3 3 2 Malarial early transcribed membrane protein (ETRAMP) Hemerythrin PF01814.18 KEP61807.1 - 0.056 13.6 2.6 0.23 11.5 0.4 2.5 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain YTH PF04146.10 KEP61810.1 - 1.6e-36 124.9 0.0 2.1e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain zf-CCCH PF00642.19 KEP61810.1 - 0.00073 19.1 11.4 0.039 13.6 2.8 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Daxx PF03344.10 KEP61811.1 - 0.66 8.3 6.7 0.68 8.3 4.7 1.0 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 KEP61811.1 - 1.2 8.9 4.7 1.4 8.7 3.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 KEP61811.1 - 1.6 6.6 4.4 1.6 6.6 3.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 KEP61811.1 - 2 7.0 6.1 2 7.0 4.2 1.0 1 0 0 1 1 1 0 Paf1 PBP1_TM PF14812.1 KEP61811.1 - 3.6 7.9 6.4 5.7 7.3 4.4 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP12 PF07542.6 KEP61812.1 - 3.4e-10 39.9 0.8 0.00017 21.5 0.0 2.7 3 0 0 3 3 3 2 ATP12 chaperone protein DUF952 PF06108.7 KEP61812.1 - 0.086 12.7 0.2 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF952) zf-B_box PF00643.19 KEP61813.1 - 4.2e-09 36.1 13.5 0.00019 21.2 1.5 2.4 2 0 0 2 2 2 2 B-box zinc finger Kinesin PF00225.18 KEP61814.1 - 6.3e-11 41.5 0.0 1.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain TMF_TATA_bd PF12325.3 KEP61814.1 - 0.16 11.6 4.6 5.6 6.7 0.2 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PHD PF00628.24 KEP61816.1 - 0.00047 19.8 6.7 0.00047 19.8 4.6 2.3 2 0 0 2 2 2 1 PHD-finger Sugar_tr PF00083.19 KEP61817.1 - 2.3e-48 164.9 28.9 4.7e-48 163.8 18.3 2.2 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KEP61817.1 - 5e-17 61.6 20.2 7.7e-17 61.0 6.3 3.2 3 0 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KEP61817.1 - 3.4e-06 25.5 1.6 3.4e-06 25.5 1.1 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Chorismate_synt PF01264.16 KEP61819.1 - 1.3e-114 382.2 0.0 5.2e-62 209.3 0.0 3.1 3 0 0 3 3 3 3 Chorismate synthase Fimbrial_PilY2 PF14481.1 KEP61820.1 - 0.012 14.9 0.2 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 RskA PF10099.4 KEP61820.1 - 0.036 13.8 1.0 0.036 13.8 0.7 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF1183 PF06682.7 KEP61820.1 - 0.065 12.8 0.1 0.081 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) SNARE_assoc PF09335.6 KEP61820.1 - 0.13 12.4 1.4 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 SNARE associated Golgi protein CcmD PF04995.9 KEP61820.1 - 0.15 11.8 0.5 0.15 11.8 0.3 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) TrbC PF04956.8 KEP61820.1 - 0.49 10.4 2.5 1.4 9.0 0.4 2.1 2 1 0 2 2 2 0 TrbC/VIRB2 family PepSY_TM_2 PF13703.1 KEP61820.1 - 4.7 7.4 7.7 1.2 9.3 0.9 2.4 1 1 1 2 2 2 0 PepSY-associated TM helix SAP18 PF06487.7 KEP61821.1 - 5.7e-30 103.5 0.0 9.1e-30 102.9 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) RNB PF00773.14 KEP61822.1 - 6.6e-77 258.9 0.0 2.6e-76 257.0 0.0 1.8 1 1 0 1 1 1 1 RNB domain Peptidase_S49_N PF08496.5 KEP61822.1 - 1.5 8.6 4.5 3.1 7.5 3.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1042 PF06294.6 KEP61823.1 - 2.6e-08 33.6 1.5 4e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1042) AAA_17 PF13207.1 KEP61823.1 - 6.4e-05 23.7 0.0 6.4e-05 23.7 0.0 3.3 3 1 0 3 3 3 1 AAA domain ADK PF00406.17 KEP61823.1 - 0.00049 20.0 1.6 1.2 8.9 0.0 3.7 3 0 0 3 3 3 2 Adenylate kinase AAA_18 PF13238.1 KEP61823.1 - 0.033 14.4 0.0 0.033 14.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain Pkinase PF00069.20 KEP61824.1 - 4e-48 163.8 0.0 8.9e-32 110.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61824.1 - 2.8e-31 108.5 0.0 6.1e-24 84.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP61824.1 - 2e-05 23.7 0.0 0.00016 20.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEP61824.1 - 0.34 10.2 0.0 0.61 9.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Mlo PF03094.10 KEP61825.1 - 2.6e-05 22.5 15.8 0.075 11.1 6.6 4.0 2 1 1 3 3 3 3 Mlo family Herpes_UL49_5 PF05702.6 KEP61825.1 - 0.42 10.5 0.1 0.42 10.5 0.0 2.8 3 0 0 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein Pkinase PF00069.20 KEP61826.1 - 2.8e-41 141.4 0.0 7.9e-40 136.6 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61826.1 - 1.1e-14 54.1 0.0 3.4e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEP61826.1 - 0.03 13.3 0.1 0.072 12.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEP61826.1 - 0.63 8.9 0.1 2.2 7.1 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.6 KEP61826.1 - 1.7 7.4 0.1 2.5 6.8 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_4 PF14570.1 KEP61827.1 - 1e-19 69.8 10.7 1.8e-19 69.0 7.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KEP61827.1 - 3.6e-05 23.3 6.8 6e-05 22.6 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 KEP61827.1 - 5.1e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP61827.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 KEP61827.1 - 0.0029 17.4 11.0 0.0046 16.7 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEP61827.1 - 0.015 14.9 8.9 0.025 14.2 6.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP61827.1 - 0.039 13.9 10.2 0.064 13.3 7.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KEP61827.1 - 0.068 12.9 3.4 0.2 11.4 2.4 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger RRM_6 PF14259.1 KEP61827.1 - 0.09 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 KEP61827.1 - 2.1 8.0 1.9 3.3 7.4 1.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.1 KEP61827.1 - 6.2 6.6 8.3 11 5.8 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.20 KEP61829.1 - 6e-14 51.8 0.0 1.1e-05 24.7 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61829.1 - 0.00051 19.2 0.0 0.042 12.9 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase RAP PF08373.5 KEP61831.1 - 9.7e-08 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RAP domain GTP1_OBG PF01018.17 KEP61832.1 - 7.1e-28 97.2 8.0 7.1e-14 51.7 0.3 3.9 3 1 0 3 3 3 3 GTP1/OBG DUF1967 PF09269.6 KEP61832.1 - 2.5e-05 23.8 0.3 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) PduV-EutP PF10662.4 KEP61832.1 - 0.0037 16.7 0.0 0.7 9.3 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KEP61832.1 - 0.017 14.5 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KEP61832.1 - 0.095 12.2 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L37e PF01907.14 KEP61833.1 - 9.9e-25 86.1 13.9 2e-24 85.1 9.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.13 KEP61833.1 - 0.002 17.8 0.2 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KEP61833.1 - 0.0024 17.6 1.7 0.005 16.6 1.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon DUF2931 PF11153.3 KEP61833.1 - 0.097 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) zf-RING_5 PF14634.1 KEP61833.1 - 0.65 9.7 5.6 0.17 11.6 1.7 1.7 2 0 0 2 2 2 0 zinc-RING finger domain BolA PF01722.13 KEP61834.1 - 4.8e-23 80.9 0.1 6.9e-23 80.4 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein Rib_5-P_isom_A PF06026.9 KEP61835.1 - 6.8e-50 168.7 0.0 1.1e-48 164.7 0.0 2.0 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KEP61835.1 - 0.00069 19.2 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.8 KEP61835.1 - 0.044 12.6 0.0 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 Putative sugar-binding domain Senescence PF06911.7 KEP61838.1 - 3.1 7.4 6.8 4.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Senescence-associated protein Histone PF00125.19 KEP61839.1 - 2.6e-14 53.0 0.1 3.1e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KEP61839.1 - 0.00015 21.9 0.0 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KEP61839.1 - 0.00034 20.4 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KEP61839.1 - 0.00046 20.1 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KEP61839.1 - 0.0028 16.9 0.0 0.003 16.8 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KEP61839.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 KEP61839.1 - 0.054 13.2 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DAGK_acc PF00609.14 KEP61840.1 - 5e-39 134.0 0.0 3.4e-23 82.5 0.0 2.3 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KEP61840.1 - 3.9e-18 65.1 0.0 3e-17 62.2 0.0 2.3 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 KEP61840.1 - 7.8e-13 47.9 19.1 8e-08 31.8 5.9 3.7 4 1 0 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.12 KEP61841.1 - 1.3e-48 165.3 0.0 8.6e-29 100.3 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 KEP61841.1 - 4.4e-48 163.7 0.0 1.9e-46 158.3 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain MORN PF02493.15 KEP61841.1 - 6.5e-05 22.4 17.9 0.016 14.8 0.1 5.0 4 0 0 4 4 4 3 MORN repeat SAM_2 PF07647.12 KEP61841.1 - 8.9e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEP61841.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nucleo_P87 PF07267.6 KEP61841.1 - 5 5.6 2.6 11 4.6 1.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PIH1 PF08190.7 KEP61842.1 - 0.0071 15.8 0.1 0.0071 15.8 0.0 1.6 2 0 0 2 2 2 1 pre-RNA processing PIH1/Nop17 LRR_4 PF12799.2 KEP61843.1 - 4.8e-14 51.5 26.6 1.1e-05 24.8 3.5 3.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KEP61843.1 - 5.6e-10 39.0 2.4 1.1e-09 38.1 1.7 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KEP61843.1 - 5e-07 29.3 11.6 5.9e-06 25.9 5.5 2.8 1 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 KEP61843.1 - 0.053 13.5 11.3 1.7 8.9 0.2 4.7 3 1 1 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KEP61843.1 - 0.71 10.3 7.9 46 4.8 0.0 5.0 4 1 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KEP61843.1 - 1.2 9.3 13.1 13 6.1 0.2 5.0 3 1 1 4 4 4 0 Leucine Rich repeat Ribosomal_S7e PF01251.13 KEP61844.1 - 6.5e-67 224.7 9.1 7.3e-67 224.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SAG PF04092.8 KEP61845.1 - 2e-20 73.4 18.6 2.1e-11 44.2 3.4 2.2 2 0 0 2 2 2 2 SRS domain Lipoprotein_2 PF00921.12 KEP61845.1 - 0.0096 15.9 4.3 0.014 15.4 2.6 1.5 1 1 0 1 1 1 1 Borrelia lipoprotein Ribosomal_L23eN PF03939.8 KEP61846.1 - 0.039 13.9 3.7 0.039 13.9 2.6 2.9 2 2 0 2 2 2 0 Ribosomal protein L23, N-terminal domain Mito_carr PF00153.22 KEP61847.1 - 3.4e-48 161.2 1.0 6.6e-25 86.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Herpes_DNAp_acc PF04929.7 KEP61847.1 - 7.6 5.3 16.8 0.35 9.8 1.8 2.1 2 0 0 2 2 2 0 Herpes DNA replication accessory factor zf-C2H2_2 PF12756.2 KEP61848.1 - 8.9e-18 64.2 1.3 2e-15 56.7 0.0 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KEP61848.1 - 0.4 10.8 0.1 0.4 10.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEP61848.1 - 2.6 8.3 12.1 1.3 9.3 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RAP1 PF07218.6 KEP61849.1 - 0.16 10.0 3.2 0.32 9.0 2.2 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ABC_membrane PF00664.18 KEP61850.1 - 2.4e-91 305.9 15.1 7.2e-47 160.0 3.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEP61850.1 - 3.8e-67 224.8 0.2 1e-32 113.2 0.0 3.7 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 KEP61850.1 - 2.7e-13 49.6 4.8 0.00013 21.2 0.1 4.1 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEP61850.1 - 8.4e-11 42.3 0.0 0.076 12.9 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 KEP61850.1 - 5.6e-10 40.0 0.0 0.00064 20.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEP61850.1 - 3.2e-09 36.1 0.1 0.00057 19.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEP61850.1 - 1.3e-08 34.1 0.0 0.0045 16.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEP61850.1 - 1.7e-08 34.6 2.0 0.0031 17.6 0.0 4.0 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KEP61850.1 - 1e-07 30.9 1.7 0.013 14.1 0.1 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KEP61850.1 - 1.5e-07 31.5 5.4 0.0049 16.8 0.6 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 KEP61850.1 - 2e-06 28.1 0.0 0.046 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEP61850.1 - 2.9e-06 26.8 0.3 0.96 8.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.9 KEP61850.1 - 1.8e-05 24.4 0.4 0.21 11.2 0.0 3.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) G-alpha PF00503.15 KEP61850.1 - 2.2e-05 23.3 0.0 0.0058 15.3 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_28 PF13521.1 KEP61850.1 - 2.3e-05 24.4 0.1 0.27 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEP61850.1 - 0.0003 20.6 0.0 0.79 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 KEP61850.1 - 0.00049 19.6 0.0 0.26 10.7 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 KEP61850.1 - 0.00078 19.6 1.7 0.59 10.3 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KEP61850.1 - 0.00089 19.1 0.2 1.5 8.7 0.0 3.2 4 0 0 4 4 2 1 AAA domain PRK PF00485.13 KEP61850.1 - 0.00098 18.7 0.0 0.44 10.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 KEP61850.1 - 0.0014 18.1 0.1 2 7.8 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 KEP61850.1 - 0.002 17.8 0.1 0.69 9.6 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KEP61850.1 - 0.002 17.8 3.0 0.84 9.2 0.0 3.3 4 0 0 4 4 3 1 NACHT domain Miro PF08477.8 KEP61850.1 - 0.0024 18.3 0.0 3.5 8.1 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein SbcCD_C PF13558.1 KEP61850.1 - 0.0024 17.7 9.1 0.028 14.3 0.3 4.0 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KEP61850.1 - 0.0026 17.2 0.1 1.7 7.9 0.0 3.7 4 0 0 4 4 4 1 AAA-like domain DUF815 PF05673.8 KEP61850.1 - 0.0038 16.1 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KEP61850.1 - 0.0045 17.1 0.0 3.8 7.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 KEP61850.1 - 0.0053 16.4 0.2 1.4 8.5 0.0 2.7 3 0 0 3 3 2 1 Adenylylsulphate kinase PduV-EutP PF10662.4 KEP61850.1 - 0.0056 16.1 0.1 3.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KEP61850.1 - 0.0064 16.3 0.9 0.89 9.3 0.1 2.7 2 1 0 2 2 2 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KEP61850.1 - 0.0068 16.3 0.0 5.3 7.0 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KEP61850.1 - 0.0085 15.2 0.1 0.47 9.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin CPT PF07931.7 KEP61850.1 - 0.011 15.3 0.1 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein UPF0079 PF02367.12 KEP61850.1 - 0.024 14.2 0.1 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 KEP61850.1 - 0.026 13.3 0.2 6.5 5.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 KEP61850.1 - 0.03 13.0 0.1 0.66 8.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 KEP61850.1 - 0.033 14.2 0.0 6.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 KEP61850.1 - 0.043 14.1 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KEP61850.1 - 0.078 11.9 0.0 13 4.6 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain ATP_bind_1 PF03029.12 KEP61850.1 - 0.084 12.4 0.1 6.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Herpes_Helicase PF02689.9 KEP61850.1 - 0.19 9.4 0.0 1.2 6.8 0.0 1.9 2 0 0 2 2 2 0 Helicase KaiC PF06745.8 KEP61850.1 - 0.19 10.7 1.4 2.3 7.2 0.0 2.7 3 0 0 3 3 2 0 KaiC TrkA_N PF02254.13 KEP61850.1 - 0.23 11.4 6.3 0.7 9.9 0.0 3.5 3 0 0 3 3 3 0 TrkA-N domain DEAD PF00270.24 KEP61850.1 - 0.24 10.8 4.4 16 4.9 0.0 3.8 3 1 1 4 4 4 0 DEAD/DEAH box helicase Ion_trans_2 PF07885.11 KEP61852.1 - 1.1e-10 41.0 3.6 3.3e-10 39.5 2.5 1.8 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 KEP61852.1 - 9.1e-08 31.9 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit MSP1_C PF07462.6 KEP61852.1 - 2.1 6.6 0.2 3.6 5.8 0.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF373 PF04123.8 KEP61852.1 - 6.7 5.6 4.4 12 4.7 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SOBP PF15279.1 KEP61855.1 - 0.0052 17.2 10.0 0.0052 17.2 6.9 6.7 4 2 2 6 6 6 1 Sine oculis-binding protein EF-hand_7 PF13499.1 KEP61857.1 - 2e-07 31.0 0.5 0.0002 21.4 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP61857.1 - 3.3e-07 29.6 1.0 0.25 11.3 0.0 3.9 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KEP61857.1 - 1.4e-06 27.1 2.3 0.35 10.2 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KEP61857.1 - 0.0025 17.3 2.7 0.21 11.2 0.3 3.4 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.1 KEP61857.1 - 0.1 12.5 0.2 9.9 6.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain 2-Hacid_dh PF00389.25 KEP61857.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain FA_desaturase PF00487.19 KEP61858.1 - 8.5e-13 48.3 16.0 8.5e-13 48.3 11.1 6.3 2 2 4 6 6 6 1 Fatty acid desaturase DUF639 PF04842.7 KEP61858.1 - 0.26 9.3 0.0 0.57 8.2 0.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Epimerase PF01370.16 KEP61859.1 - 5.4e-67 225.6 0.0 6.7e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEP61859.1 - 1.3e-10 40.6 0.0 1.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase_Csub PF13950.1 KEP61859.1 - 0.0065 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 KEP61859.1 - 0.051 12.4 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RRN3 PF05327.6 KEP61863.1 - 8.1e-58 195.8 0.0 8.1e-58 195.8 0.0 3.2 4 1 0 4 4 4 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3223 PF11523.3 KEP61863.1 - 1.9e-07 31.2 0.4 3.1e-06 27.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) RRM_6 PF14259.1 KEP61864.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SAG PF04092.8 KEP61866.1 - 1.6e-06 28.5 0.4 2.1e-06 28.1 0.3 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.8 KEP61867.1 - 1.2e-08 35.3 1.9 1.7e-08 34.9 1.3 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.8 KEP61868.1 - 6.6e-07 29.7 0.6 8.7e-07 29.3 0.4 1.1 1 0 0 1 1 1 1 SRS domain zf-RanBP PF00641.13 KEP61869.1 - 0.045 12.8 2.7 0.11 11.6 1.9 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others SAG PF04092.8 KEP61870.1 - 2.9e-08 34.1 0.2 4.3e-08 33.5 0.1 1.3 1 1 0 1 1 1 1 SRS domain SAG PF04092.8 KEP61871.1 - 1.2e-07 32.1 0.8 1.7e-07 31.6 0.4 1.4 1 1 0 1 1 1 1 SRS domain SAG PF04092.8 KEP61872.1 - 9.5e-07 29.2 0.1 1.4e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 SRS domain DUF4044 PF13253.1 KEP61872.1 - 1.1 8.4 8.5 4.8 6.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Form-deh_trans PF09163.6 KEP61872.1 - 8.6 5.9 6.8 0.96 8.9 1.5 1.8 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane SAG PF04092.8 KEP61873.1 - 4e-08 33.6 0.3 6.6e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 SRS domain But2 PF09792.4 KEP61873.1 - 0.028 14.1 0.8 5.6 6.7 0.0 2.7 1 1 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain SAG PF04092.8 KEP61874.1 - 2.5e-10 40.7 1.3 3.3e-10 40.4 0.9 1.2 1 0 0 1 1 1 1 SRS domain Chitin_bind_3 PF03067.10 KEP61874.1 - 0.018 15.2 0.1 0.023 14.9 0.1 1.2 1 0 0 1 1 1 0 Chitin binding domain Bac_export_3 PF01313.14 KEP61874.1 - 0.063 12.9 0.7 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Bacterial export proteins, family 3 SAG PF04092.8 KEP61876.1 - 8.3e-11 42.3 0.6 1.2e-10 41.8 0.4 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.8 KEP61877.1 - 1.1e-08 35.4 2.8 1.8e-08 34.7 1.9 1.3 1 0 0 1 1 1 1 SRS domain Rubredoxin PF00301.15 KEP61879.1 - 0.07 13.0 0.4 0.27 11.1 0.3 2.1 1 0 0 1 1 1 0 Rubredoxin Syja_N PF02383.13 KEP61880.1 - 1.4e-59 201.4 0.0 8.5e-57 192.3 0.0 3.2 2 1 0 2 2 2 2 SacI homology domain Exo_endo_phos PF03372.18 KEP61880.1 - 1e-18 68.2 0.3 1.2e-16 61.4 0.0 3.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family NRDE-2 PF08424.5 KEP61882.1 - 0.077 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Ribosomal_L36e PF01158.13 KEP61885.1 - 3.7e-36 123.0 4.0 4.2e-36 122.8 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Bystin PF05291.6 KEP61886.1 - 2.5e-113 378.0 0.2 3.7e-113 377.4 0.1 1.2 1 0 0 1 1 1 1 Bystin Spt5_N PF11942.3 KEP61886.1 - 1.5 9.4 12.7 0.22 12.1 5.5 2.0 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DBR1 PF05011.8 KEP61887.1 - 8.2e-19 67.9 0.0 1.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KEP61887.1 - 1.1e-15 57.6 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEP61887.1 - 2.1e-06 27.6 0.0 3.7e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 KEP61887.1 - 0.0015 17.7 0.0 0.0062 15.7 0.0 2.1 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily EGF PF00008.22 KEP61888.1 - 3.9e-08 33.1 54.4 0.00016 21.5 4.4 5.9 5 1 0 5 5 5 4 EGF-like domain EGF_3 PF12947.2 KEP61888.1 - 0.00053 19.8 39.6 0.31 11.0 8.5 5.2 4 1 0 4 4 4 4 EGF domain cEGF PF12662.2 KEP61888.1 - 0.00059 19.4 28.4 0.042 13.5 0.8 5.9 5 0 0 5 5 5 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP61888.1 - 0.31 11.1 48.4 0.041 14.0 3.2 5.3 4 1 1 5 5 5 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 KEP61888.1 - 5.4 7.3 33.3 1.8 8.8 1.6 6.4 6 0 0 6 6 6 0 Human growth factor-like EGF EGF PF00008.22 KEP61889.1 - 0.0098 15.8 8.2 0.0098 15.8 5.7 5.8 5 0 0 5 5 5 3 EGF-like domain cEGF PF12662.2 KEP61889.1 - 0.025 14.1 0.8 0.025 14.1 0.5 5.2 5 0 0 5 5 5 0 Complement Clr-like EGF-like Abhydrolase_3 PF07859.8 KEP61890.1 - 1.3e-36 126.1 0.0 1.9e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEP61890.1 - 0.00039 20.2 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KEP61890.1 - 0.0061 15.3 0.0 0.014 14.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KEP61890.1 - 0.025 13.2 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KEP61890.1 - 0.051 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family RNA_pol_A_bac PF01000.21 KEP61891.1 - 2.3e-26 92.1 0.0 5.2e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KEP61891.1 - 1.3e-16 59.4 0.0 1.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RPN7 PF10602.4 KEP61892.1 - 6.4e-54 182.0 0.7 9.7e-54 181.4 0.5 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KEP61892.1 - 8e-14 51.8 0.1 3.9e-13 49.6 0.0 2.2 3 0 0 3 3 3 1 PCI domain TPR_14 PF13428.1 KEP61892.1 - 0.00028 21.2 1.5 0.77 10.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP61892.1 - 0.0089 15.8 1.5 0.52 10.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEP61892.1 - 0.054 13.1 0.1 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.1 KEP61892.1 - 0.068 12.9 0.1 1.4 8.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat FeoC PF09012.5 KEP61892.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator HXXEE PF13787.1 KEP61897.1 - 2e-15 57.1 0.1 2e-15 57.1 0.1 2.8 4 0 0 4 4 4 1 Protein of unknown function with HXXEE motif Form-deh_trans PF09163.6 KEP61897.1 - 0.74 9.3 7.1 0.16 11.4 1.4 2.5 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Rep_fac-A_3 PF08661.6 KEP61898.1 - 2.1e-09 37.2 0.0 2.5e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-like PF12869.2 KEP61898.1 - 0.096 12.1 0.1 0.41 10.1 0.1 1.9 1 1 0 1 1 1 0 tRNA_anti-like YajC PF02699.10 KEP61898.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit tRNA_anti-codon PF01336.20 KEP61898.1 - 0.17 11.8 0.5 7.8 6.4 0.2 2.1 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain EMP24_GP25L PF01105.19 KEP61899.1 - 9.4e-39 133.0 0.2 1.1e-38 132.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF912 PF06024.7 KEP61899.1 - 0.022 14.8 0.2 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Matrilin_ccoil PF10393.4 KEP61899.1 - 0.087 12.2 0.8 0.18 11.1 0.6 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-HIT PF04438.11 KEP61900.1 - 0.024 14.2 8.1 0.054 13.1 5.6 1.6 1 0 0 1 1 1 0 HIT zinc finger Glutaredoxin PF00462.19 KEP61902.1 - 3.6e-15 55.6 0.0 8.2e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.15 KEP61902.1 - 7.4e-06 25.5 0.0 2.2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 KEP61902.1 - 3.6e-05 23.9 0.0 0.00028 21.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain HyaE PF07449.6 KEP61902.1 - 0.00041 20.2 0.0 0.16 11.8 0.0 2.8 1 1 1 2 2 2 2 Hydrogenase-1 expression protein HyaE EF-hand_7 PF13499.1 KEP61903.1 - 3e-14 52.9 1.5 6.7e-11 42.1 0.2 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 KEP61903.1 - 9.4e-12 44.3 2.0 6.2e-07 28.9 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 KEP61903.1 - 2.2e-10 39.0 0.1 0.00055 19.0 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KEP61903.1 - 3.6e-10 38.8 0.9 0.00033 20.2 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 KEP61903.1 - 9.4e-08 31.0 3.7 0.0036 16.5 0.0 3.4 3 0 0 3 3 3 2 EF hand PepSY_2 PF13670.1 KEP61903.1 - 0.016 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Excalibur PF05901.6 KEP61903.1 - 0.047 14.0 0.4 18 5.7 0.0 3.3 3 0 0 3 3 3 0 Excalibur calcium-binding domain SNase PF00565.12 KEP61904.1 - 1.7e-57 192.3 0.1 3.7e-17 62.5 0.0 5.9 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KEP61904.1 - 1.7e-22 79.5 0.0 6.3e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Tudor domain Glyco_transf_90 PF05686.7 KEP61905.1 - 9.4e-68 228.6 0.0 1.4e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin PF00085.15 KEP61905.1 - 6.3e-55 183.2 0.0 6.4e-23 80.4 0.0 4.4 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_7 PF13899.1 KEP61905.1 - 2e-09 37.3 0.0 0.0017 18.3 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KEP61905.1 - 2e-08 34.4 0.5 0.0035 17.5 0.1 4.5 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEP61905.1 - 8.2e-07 29.0 0.1 0.57 10.3 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 KEP61905.1 - 0.0037 17.1 0.0 15 5.3 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin-like domain Glyco_trans_1_2 PF13524.1 KEP61905.1 - 0.0082 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Thioredoxin_9 PF14595.1 KEP61905.1 - 0.02 14.4 0.0 15 5.1 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin YTH PF04146.10 KEP61906.1 - 7.6e-13 48.2 0.0 1.3e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain BBS2_C PF14782.1 KEP61906.1 - 0.25 9.8 1.0 0.35 9.3 0.7 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal His_Phos_2 PF00328.17 KEP61907.1 - 4.1e-12 46.1 6.7 1.7e-07 30.8 0.0 4.4 5 0 0 5 5 5 3 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 KEP61908.1 - 2.3e-34 118.7 0.0 9e-12 44.6 0.0 4.4 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61908.1 - 2.2e-17 63.0 0.0 6.8e-10 38.4 0.0 3.5 4 1 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP61908.1 - 0.065 12.1 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CWC25 PF12542.3 KEP61910.1 - 2.6e-16 59.8 0.0 2.6e-16 59.8 0.0 5.0 5 1 0 5 5 5 1 Pre-mRNA splicing factor MACPF PF01823.14 KEP61911.1 - 1.2e-48 165.5 1.8 3.3e-48 164.1 0.0 2.6 3 0 0 3 3 3 1 MAC/Perforin domain zf-RING_2 PF13639.1 KEP61912.1 - 4.2e-09 36.1 6.7 4.2e-09 36.1 4.7 2.9 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.24 KEP61912.1 - 4.5e-09 35.8 8.8 4.5e-09 35.8 6.1 3.1 3 0 0 3 3 3 1 PHD-finger zf-C3HC4 PF00097.20 KEP61912.1 - 1.6e-07 30.8 6.8 1.6e-07 30.8 4.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP61912.1 - 7.9e-06 25.4 3.3 7.9e-06 25.4 2.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP61912.1 - 1.4e-05 25.1 4.2 4.1e-05 23.6 2.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEP61912.1 - 4.3e-05 23.1 6.6 4.3e-05 23.1 4.6 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP61912.1 - 0.0004 20.3 7.7 0.0004 20.3 5.4 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.1 KEP61912.1 - 0.0095 15.2 3.5 0.022 14.0 0.5 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain eIF2A PF08662.6 KEP61914.1 - 1.3e-47 162.0 0.0 1.7e-39 135.5 0.0 3.8 4 0 0 4 4 4 3 Eukaryotic translation initiation factor eIF2A GYF PF02213.11 KEP61914.1 - 5.5e-14 51.4 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 GYF domain WD40 PF00400.27 KEP61914.1 - 0.0019 18.0 0.2 7.5 6.6 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat BLOC1_2 PF10046.4 KEP61914.1 - 0.46 10.6 0.0 0.99 9.5 0.0 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PRNT PF15174.1 KEP61915.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Prion-related protein testis-specific Pkinase PF00069.20 KEP61916.1 - 5.1e-43 147.1 0.0 1e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61916.1 - 3e-12 46.1 0.1 7.7e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Daxx PF03344.10 KEP61917.1 - 1.4 7.3 10.2 2.4 6.5 7.1 1.3 1 0 0 1 1 1 0 Daxx Family Y_Y_Y PF07495.8 KEP61919.1 - 0.61 9.8 0.5 65 3.3 0.0 3.8 4 1 0 4 4 4 0 Y_Y_Y domain CompInhib_SCIN PF11546.3 KEP61921.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN Pro_isomerase PF00160.16 KEP61922.1 - 1.6e-19 70.5 0.0 3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4156 PF13698.1 KEP61922.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) TrmE_N PF10396.4 KEP61924.1 - 1.2e-17 63.9 0.1 1.1e-08 34.9 0.0 3.5 3 0 0 3 3 3 3 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 KEP61924.1 - 3.2e-15 56.0 0.0 5.6e-14 52.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEP61924.1 - 5.4e-05 23.0 0.0 0.00015 21.5 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GTPase_Cys_C PF12631.2 KEP61924.1 - 0.00023 21.4 0.1 0.00023 21.4 0.1 2.5 3 0 0 3 3 3 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 KEP61924.1 - 0.00035 19.8 0.0 0.00059 19.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KEP61924.1 - 0.0059 17.0 0.0 0.43 11.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 KEP61924.1 - 0.012 15.9 0.8 0.027 14.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 KEP61924.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KEP61924.1 - 0.095 12.1 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MobB PF03205.9 KEP61924.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_S8 PF00082.17 KEP61926.1 - 1.6e-45 155.4 4.6 2.6e-45 154.7 3.2 1.4 1 0 0 1 1 1 1 Subtilase family MPC PF03650.8 KEP61927.1 - 8e-30 103.2 0.8 9.7e-30 102.9 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 KEP61927.1 - 0.061 13.1 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange 2OG-FeII_Oxy_2 PF13532.1 KEP61929.1 - 2.4e-05 24.2 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2217 PF10265.4 KEP61929.1 - 0.94 8.1 5.8 1.5 7.5 4.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SpoIIIAH PF12685.2 KEP61929.1 - 1.5 8.3 5.2 2.6 7.5 3.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2890 PF11081.3 KEP61930.1 - 3.4 7.6 12.8 7.5 6.5 5.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) ATP-synt_ab PF00006.20 KEP61932.1 - 1e-70 237.6 0.0 1.4e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEP61932.1 - 2.9e-23 82.4 0.0 5.9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEP61932.1 - 4.1e-17 62.1 4.3 1.2e-16 60.6 3.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KEP61932.1 - 2.5e-07 30.4 2.2 5.8e-07 29.3 1.5 1.6 1 0 0 1 1 1 1 HAS barrel domain Exo_endo_phos PF03372.18 KEP61933.1 - 8e-12 45.6 0.0 1.2e-10 41.8 0.0 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family cEGF PF12662.2 KEP61934.1 - 6.5e-06 25.6 58.7 1.1 9.0 0.7 13.2 13 0 0 13 13 13 6 Complement Clr-like EGF-like TIL PF01826.12 KEP61934.1 - 0.016 15.2 50.4 1.4 9.0 0.3 11.3 7 4 2 9 9 9 0 Trypsin Inhibitor like cysteine rich domain SH3_5 PF08460.5 KEP61934.1 - 0.033 14.0 0.0 17 5.3 0.0 4.2 5 1 1 6 6 6 0 Bacterial SH3 domain Antistasin PF02822.9 KEP61934.1 - 0.046 14.0 0.2 0.046 14.0 0.1 10.9 13 0 0 13 13 13 0 Antistasin family Calcyon PF06387.6 KEP61934.1 - 0.13 11.5 17.8 1.4 8.2 0.1 7.0 6 2 2 8 8 8 0 D1 dopamine receptor-interacting protein (calcyon) EB PF01683.13 KEP61934.1 - 0.84 9.7 37.8 1 9.4 0.1 9.9 5 4 3 8 8 8 0 EB module Tme5_EGF_like PF09064.5 KEP61934.1 - 2.9 7.5 39.4 4.2 7.0 0.1 10.8 11 1 0 11 11 11 0 Thrombomodulin like fifth domain, EGF-like cNMP_binding PF00027.24 KEP61935.1 - 6.7e-18 64.2 0.0 8e-13 48.0 0.0 3.6 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain HMGL-like PF00682.14 KEP61936.1 - 5.6e-38 130.9 0.2 3.4e-37 128.3 0.1 2.1 2 0 0 2 2 2 1 HMGL-like cNMP_binding PF00027.24 KEP61938.1 - 2.7e-15 55.9 0.0 5.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pneumo_ncap PF03246.8 KEP61938.1 - 0.00017 20.2 0.0 0.00021 19.9 0.0 1.1 1 0 0 1 1 1 1 Pneumovirus nucleocapsid protein DnaJ PF00226.26 KEP61939.1 - 1.8e-23 82.0 1.4 3.6e-23 81.0 1.0 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_6 PF13848.1 KEP61939.1 - 1.4e-12 47.8 0.1 5.3e-07 29.6 0.0 3.1 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin PF00085.15 KEP61939.1 - 2.3e-11 43.3 0.0 2.5e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin BUD22 PF09073.5 KEP61940.1 - 2.6 6.9 63.3 0.72 8.8 26.6 2.1 2 0 0 2 2 2 0 BUD22 DUF2570 PF10828.3 KEP61941.1 - 0.024 14.2 4.8 1.8 8.2 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) WD40 PF00400.27 KEP61942.1 - 2.4e-09 36.6 0.3 0.00012 21.8 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat CPL PF08144.6 KEP61944.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 CPL (NUC119) domain DUF367 PF04034.8 KEP61945.1 - 6.4e-35 119.5 0.0 9.2e-35 119.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KEP61945.1 - 7.5e-08 31.8 0.9 1.5e-07 30.8 0.6 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AMP-binding PF00501.23 KEP61946.1 - 0.0064 14.9 0.3 0.21 9.9 0.0 3.0 4 1 0 4 4 4 1 AMP-binding enzyme DUF2313 PF10076.4 KEP61946.1 - 0.089 12.1 0.5 0.3 10.4 0.1 2.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2313) ketoacyl-synt PF00109.21 KEP61947.1 - 1e-67 228.3 0.0 1.7e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEP61947.1 - 1.9e-50 171.0 0.2 1.9e-50 171.0 0.1 2.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KEP61947.1 - 7.6e-39 133.3 8.2 1.2e-38 132.6 0.1 3.9 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEP61947.1 - 2.5e-32 111.2 0.4 4.9e-32 110.2 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KEP61947.1 - 2.2e-31 108.6 0.0 1e-28 99.9 0.0 3.7 4 0 0 4 4 4 1 Male sterility protein PP-binding PF00550.20 KEP61947.1 - 1.7e-11 44.2 0.4 3.7e-11 43.1 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KEP61947.1 - 2.9e-05 23.6 2.9 0.12 11.7 0.0 3.8 4 1 0 4 4 4 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEP61947.1 - 0.001 18.0 0.0 0.78 8.5 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.5 KEP61948.1 - 1.2e-55 188.0 1.2 2.9e-55 186.7 0.1 2.2 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 KEP61948.1 - 1e-45 155.6 1.9 6.6e-45 153.0 0.5 2.7 2 1 0 2 2 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 KEP61948.1 - 6.5e-37 127.5 0.2 2.6e-32 112.4 0.4 2.3 2 0 0 2 2 2 2 Acyl transferase domain PP-binding PF00550.20 KEP61948.1 - 2.3e-12 46.9 0.2 6.7e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site PS-DH PF14765.1 KEP61948.1 - 1.1e-09 37.8 0.1 4.4e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 Polyketide synthase dehydratase Polysacc_synt_2 PF02719.10 KEP61948.1 - 0.00015 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KEP61948.1 - 0.046 13.1 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.21 KEP61949.1 - 9.4e-73 244.8 0.1 1.3e-72 244.3 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.20 KEP61949.1 - 8.1e-12 45.2 0.0 1.9e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.1 KEP61949.1 - 1.7e-08 33.9 0.6 2.9e-08 33.2 0.4 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEP61949.1 - 9.1e-07 28.7 0.0 2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KEP61949.1 - 0.045 12.7 0.1 0.077 11.9 0.1 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KEP61950.1 - 2e-149 496.0 2.2 1.2e-74 251.0 0.1 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEP61950.1 - 2.1e-49 166.2 0.3 9.7e-37 125.4 0.0 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEP61950.1 - 9.2e-13 48.2 0.6 4.2e-12 46.1 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KEP61950.1 - 3e-06 26.4 3.0 0.0014 17.6 0.0 2.5 2 0 0 2 2 2 2 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.7 KEP61950.1 - 0.011 14.7 0.1 0.025 13.6 0.1 1.5 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 KEP61950.1 - 0.033 13.8 5.4 0.59 9.8 0.2 3.4 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III His_Phos_1 PF00300.17 KEP61953.1 - 2.7e-13 50.3 1.1 1.1e-09 38.6 0.4 3.2 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SF3b1 PF08920.5 KEP61954.1 - 7.6e-36 123.3 6.3 7e-29 100.7 0.1 3.8 2 1 1 3 3 3 3 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KEP61954.1 - 6.8e-13 48.7 7.3 0.0076 16.5 0.0 7.6 5 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 KEP61954.1 - 1.5e-08 34.8 5.1 0.23 12.0 0.0 8.4 9 1 1 10 10 10 2 HEAT-like repeat HEAT PF02985.17 KEP61954.1 - 2.9e-06 26.9 14.6 1.1 9.4 0.1 8.9 11 0 0 11 11 11 2 HEAT repeat UME PF08064.8 KEP61954.1 - 3.9e-06 26.7 0.3 0.18 11.7 0.0 4.6 4 0 0 4 4 4 1 UME (NUC010) domain Arm PF00514.18 KEP61954.1 - 0.00015 21.4 0.4 30 4.6 0.0 5.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ParcG PF10274.4 KEP61954.1 - 0.0016 18.3 1.6 7.6 6.3 0.0 4.4 2 1 1 4 4 4 1 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 KEP61954.1 - 0.0085 16.4 0.4 37 4.7 0.0 5.5 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 KEP61954.1 - 0.02 14.7 7.2 2.1 8.3 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) CRM1_C PF08767.6 KEP61954.1 - 0.15 10.9 0.1 0.62 8.9 0.0 2.0 2 1 0 2 2 2 0 CRM1 C terminal SNARE PF05739.14 KEP61956.1 - 5.3e-07 29.2 0.7 7.1e-07 28.8 0.5 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KEP61956.1 - 0.0013 18.2 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF3753 PF12575.3 KEP61956.1 - 0.064 13.0 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF3829 PF12889.2 KEP61956.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) PGAP1 PF07819.8 KEP61957.1 - 2.9e-12 46.6 0.0 4.8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEP61957.1 - 1.3e-06 28.4 0.6 1.3e-06 28.4 0.4 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP61957.1 - 0.0026 17.5 0.0 0.008 15.9 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4131 PF13567.1 KEP61957.1 - 0.95 8.8 13.8 2.9 7.2 0.5 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Gly_transf_sug PF04488.10 KEP61959.1 - 2e-10 40.9 0.1 5.6e-09 36.3 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KEP61959.1 - 1e-07 30.8 0.3 0.0018 16.8 0.0 2.4 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 KEP61959.1 - 0.0099 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DUF2610 PF11020.3 KEP61960.1 - 0.15 11.8 0.1 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) WXG100 PF06013.7 KEP61961.1 - 0.0048 16.8 1.2 0.0048 16.8 0.9 2.2 2 1 0 2 2 2 1 Proteins of 100 residues with WXG Phage_T7_Capsid PF05396.6 KEP61961.1 - 0.0067 16.5 1.6 0.082 13.0 0.3 2.2 1 1 1 2 2 2 1 Phage T7 capsid assembly protein DUF3584 PF12128.3 KEP61961.1 - 0.014 12.8 13.2 0.016 12.5 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KIF1B PF12423.3 KEP61961.1 - 0.14 12.1 0.1 0.14 12.1 0.0 2.7 3 0 0 3 3 3 0 Kinesin protein 1B TMF_TATA_bd PF12325.3 KEP61961.1 - 0.18 11.5 21.3 0.2 11.4 4.0 3.1 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Filament PF00038.16 KEP61961.1 - 0.35 10.3 21.0 0.1 12.0 11.6 1.8 1 1 1 2 2 2 0 Intermediate filament protein DUF3347 PF11827.3 KEP61961.1 - 0.39 10.7 10.6 0.5 10.3 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Rb_C PF08934.5 KEP61961.1 - 0.49 10.0 3.0 0.83 9.2 2.1 1.4 1 0 0 1 1 1 0 Rb C-terminal domain COG5 PF10392.4 KEP61961.1 - 0.72 9.8 5.5 1.1 9.2 1.0 2.6 1 1 2 3 3 3 0 Golgi transport complex subunit 5 CDC37_N PF03234.9 KEP61961.1 - 1.5 9.0 15.0 2.4 8.4 10.4 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4407 PF14362.1 KEP61961.1 - 2.2 7.1 9.5 2.7 6.8 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.6 KEP61961.1 - 2.2 8.2 9.5 0.56 10.1 0.6 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 KEP61961.1 - 3.3 7.9 11.9 3.3 7.9 1.9 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 KEP61961.1 - 3.6 7.1 19.0 6.3 6.3 3.7 2.3 1 1 1 2 2 2 0 IncA protein DUF1041 PF06292.12 KEP61961.1 - 4.3 7.5 6.6 0.46 10.6 0.2 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1041) DivIC PF04977.10 KEP61961.1 - 5.1 6.6 17.9 0.2 11.1 2.4 3.3 1 1 3 4 4 4 0 Septum formation initiator MvaI_BcnI PF15515.1 KEP61962.1 - 0.14 12.1 0.7 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 MvaI/BcnI restriction endonuclease family TUSC2 PF15000.1 KEP61963.1 - 0.016 15.2 0.1 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Glyoxalase_2 PF12681.2 KEP61965.1 - 8.6e-12 45.6 0.0 1.5e-07 32.0 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase PF00903.20 KEP61965.1 - 8.1e-08 32.3 0.1 0.00036 20.5 0.0 3.0 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fibrinogen_BP PF08017.6 KEP61965.1 - 0.0031 15.8 23.2 0.0042 15.3 16.1 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein DUF2201_N PF13203.1 KEP61965.1 - 1.3 8.1 14.9 1.9 7.5 10.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PLRV_ORF5 PF01690.12 KEP61965.1 - 2.1 7.4 19.7 2.8 6.9 13.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AvrE PF11725.3 KEP61965.1 - 2.7 4.8 16.3 3.6 4.4 11.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor Paramyxo_ncap PF00973.14 KEP61965.1 - 4.8 5.7 14.6 7.5 5.1 10.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LMBR1 PF04791.11 KEP61965.1 - 6 5.3 8.8 8 4.9 6.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MIP-T3 PF10243.4 KEP61965.1 - 7.5 4.8 45.9 10 4.4 31.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 KEP61965.1 - 9.7 3.7 27.3 14 3.2 18.9 1.1 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 KEP61965.1 - 9.9 5.4 60.5 0.024 13.9 35.3 1.5 2 0 0 2 2 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sec7_N PF12783.2 KEP61966.1 - 2.2e-14 53.2 6.4 7e-14 51.5 0.3 3.0 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF155 PF02582.9 KEP61968.1 - 2.2e-31 109.1 0.0 9.8e-31 107.0 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RRM_1 PF00076.17 KEP61972.1 - 3.1e-23 81.1 0.1 5.4e-23 80.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP61972.1 - 1.1e-17 63.7 0.0 1.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 KEP61972.1 - 6.5e-16 58.4 1.2 6.5e-16 58.4 0.9 2.5 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 KEP61972.1 - 7.2e-11 41.7 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HDAC4_Gln PF12203.3 KEP61972.1 - 1.5 8.7 12.2 3 7.8 0.4 2.5 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 PRP38_assoc PF12871.2 KEP61972.1 - 5.3 7.6 40.2 8.5 6.9 27.6 1.6 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF676 PF05057.9 KEP61974.1 - 0.00076 18.8 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) DUF3727 PF12527.3 KEP61974.1 - 0.26 11.3 0.0 0.57 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) GvpG PF05120.7 KEP61975.1 - 0.0099 15.6 1.3 0.017 14.9 0.9 1.4 1 0 0 1 1 1 1 Gas vesicle protein G Mod_r PF07200.8 KEP61975.1 - 0.06 13.2 3.4 0.12 12.2 0.4 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3140 PF11338.3 KEP61975.1 - 0.15 12.1 1.5 0.38 10.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3140) PRP1_N PF06424.7 KEP61976.1 - 1.8e-45 154.5 17.7 1.7e-42 144.9 0.6 3.7 3 0 0 3 3 3 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KEP61976.1 - 1.5e-29 99.8 31.5 0.0054 17.2 0.4 13.9 7 3 8 15 15 13 9 Tetratricopeptide repeat TPR_19 PF14559.1 KEP61976.1 - 1.2e-19 70.3 18.3 0.005 17.1 0.0 9.6 5 2 3 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEP61976.1 - 2.5e-13 50.3 22.8 0.11 13.2 0.7 8.5 6 1 2 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 KEP61976.1 - 3.8e-12 45.6 10.6 0.063 12.9 0.0 9.7 5 3 3 9 9 9 1 TPR repeat TPR_2 PF07719.12 KEP61976.1 - 8.4e-08 31.5 19.2 0.97 9.5 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEP61976.1 - 5.4e-07 28.9 1.2 0.38 10.6 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP61976.1 - 1.5e-06 27.9 0.9 11 6.5 0.0 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP61976.1 - 1.1e-05 25.2 14.5 0.2 11.6 0.0 7.4 7 1 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEP61976.1 - 0.00056 19.4 1.2 0.42 10.3 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP61976.1 - 0.00058 19.4 2.7 0.097 12.5 0.0 5.3 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEP61976.1 - 0.0025 18.1 6.6 36 5.1 0.0 7.9 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEP61976.1 - 0.02 14.7 7.4 2.1 8.2 0.1 5.9 4 2 3 7 7 7 0 Tetratricopeptide repeat OsmC PF02566.14 KEP61976.1 - 0.05 13.7 1.3 10 6.4 0.1 3.7 3 1 0 3 3 3 0 OsmC-like protein ChAPs PF09295.5 KEP61976.1 - 0.65 8.6 6.2 2.7 6.6 0.1 3.6 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.9 KEP61976.1 - 1.2 8.8 6.7 11 5.6 0.0 4.4 5 1 1 6 6 6 0 Suppressor of forked protein (Suf) TPR_10 PF13374.1 KEP61976.1 - 7.8 6.5 6.8 6.1 6.9 0.1 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat CLPTM1 PF05602.7 KEP61977.1 - 1.8e-83 280.6 0.2 4.3e-82 276.1 0.2 2.3 3 0 0 3 3 3 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 KEP61977.1 - 1.9e-06 27.2 3.1 0.045 13.2 0.2 2.9 2 0 0 2 2 2 2 PQ loop repeat DUF1240 PF06836.7 KEP61977.1 - 0.53 10.5 8.2 0.17 12.1 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Kinase-like PF14531.1 KEP61978.1 - 1.7e-60 204.4 0.0 2.5e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP61978.1 - 6.7e-22 77.8 0.0 2.6e-20 72.6 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP61978.1 - 9.4e-08 31.4 0.0 1.4e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase TFIIS_C PF01096.13 KEP61978.1 - 0.077 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) Ion_trans PF00520.26 KEP61979.1 - 8.7e-32 109.9 59.8 1.7e-16 60.0 23.4 2.3 2 0 0 2 2 2 2 Ion transport protein Ion_trans PF00520.26 KEP61980.1 - 2.2e-42 144.6 38.5 1.2e-21 76.8 16.4 2.6 2 0 0 2 2 2 2 Ion transport protein Cob_adeno_trans PF01923.13 KEP61981.1 - 0.0038 17.0 0.3 0.0071 16.1 0.2 1.4 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DSPc PF00782.15 KEP61982.1 - 1.3e-07 31.2 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CBM_20 PF00686.14 KEP61982.1 - 0.00031 20.2 0.0 0.00094 18.7 0.0 1.8 2 0 0 2 2 2 1 Starch binding domain TauE PF01925.14 KEP61983.1 - 7.9e-26 90.9 22.9 2.6e-14 53.2 1.5 2.6 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE DUF4381 PF14316.1 KEP61983.1 - 0.035 14.1 1.0 11 6.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SieB PF14163.1 KEP61983.1 - 0.036 13.6 2.3 3.6 7.1 0.2 3.1 3 0 0 3 3 3 0 Superinfection exclusion protein B DUF3290 PF11694.3 KEP61983.1 - 0.11 12.2 2.8 0.28 10.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Spore_YhaL PF14147.1 KEP61983.1 - 0.36 10.2 5.4 0.3 10.5 0.1 2.9 2 1 0 2 2 2 0 Sporulation protein YhaL Orexin_rec2 PF03827.8 KEP61984.1 - 0.12 12.4 13.9 3.6 7.7 0.2 4.6 3 2 2 5 5 5 0 Orexin receptor type 2 Ribosomal_L7Ae PF01248.21 KEP61986.1 - 1.5e-27 94.9 1.4 1.8e-27 94.6 0.7 1.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.7 KEP61986.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Glyco_transf_4 PF13439.1 KEP61986.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Antimicrobial19 PF08225.6 KEP61986.1 - 0.18 11.1 0.7 9.2 5.7 0.0 2.8 3 0 0 3 3 3 0 Pseudin antimicrobial peptide ELO PF01151.13 KEP61987.1 - 1e-64 218.2 24.8 1.2e-64 218.0 17.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Med15 PF09606.5 KEP61987.1 - 0.024 12.8 0.3 0.033 12.4 0.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FBPase PF00316.15 KEP61990.1 - 4.5e-86 288.6 0.0 5.7e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF2481 PF10654.4 KEP61991.1 - 0.042 13.5 0.5 0.048 13.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) DUF2514 PF10721.4 KEP61991.1 - 0.23 11.1 4.9 0.25 11.0 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Helicase_C PF00271.26 KEP61993.1 - 4.1e-13 48.9 0.0 8.1e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KEP61993.1 - 0.0014 17.4 0.0 0.0067 15.2 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PseudoU_synth_2 PF00849.17 KEP61994.1 - 7.6e-19 68.1 0.0 1.4e-17 63.9 0.0 2.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4_2 PF13275.1 KEP61994.1 - 0.0019 17.7 0.0 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4 PF01479.20 KEP61994.1 - 0.0075 15.6 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain Semialdhyde_dh PF01118.19 KEP61995.1 - 2.7e-27 95.4 0.0 4.4e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 KEP61995.1 - 4.8e-21 75.4 0.0 7.1e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 KEP61995.1 - 0.00063 19.6 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 KEP61995.1 - 0.047 14.2 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Acyl-CoA_dh_1 PF00441.19 KEP61996.1 - 1.2e-36 126.0 0.1 2e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEP61996.1 - 1e-30 106.5 0.0 2.7e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEP61996.1 - 1.4e-17 62.8 0.1 3.4e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEP61996.1 - 3.2e-11 43.5 0.0 5.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KEP61996.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Cpn60_TCP1 PF00118.19 KEP61997.1 - 1.6e-157 525.0 7.6 1.9e-157 524.8 5.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dpoe2NT PF12213.3 KEP61997.1 - 0.064 13.1 0.1 3.3 7.6 0.0 2.8 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal zf-AN1 PF01428.11 KEP61999.1 - 4.8e-22 77.5 27.8 5.7e-12 45.3 5.9 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 KEP61999.1 - 0.0014 18.8 18.5 0.14 12.4 3.7 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain C1_3 PF07649.7 KEP61999.1 - 0.022 14.7 13.6 0.38 10.8 0.5 3.6 3 0 0 3 3 3 0 C1-like domain FYVE PF01363.16 KEP61999.1 - 3.3 7.6 25.4 0.46 10.4 4.5 2.6 2 1 0 2 2 2 0 FYVE zinc finger GTP_EFTU PF00009.22 KEP62000.1 - 6.9e-62 208.2 0.1 1.1e-61 207.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KEP62000.1 - 2.5e-35 120.6 0.0 7.1e-35 119.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KEP62000.1 - 5.7e-22 77.4 0.0 1.2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KEP62000.1 - 1.8e-14 53.3 0.0 3.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KEP62000.1 - 4.1e-12 46.0 0.6 2.4e-11 43.5 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEP62000.1 - 0.00027 20.8 0.0 0.00061 19.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-SAP30 PF13866.1 KEP62001.1 - 2.6 7.7 4.1 2.2 7.9 0.1 2.1 2 0 0 2 2 2 0 SAP30 zinc-finger BT1 PF03092.11 KEP62002.1 - 3.2e-78 263.4 19.9 5.3e-78 262.6 13.8 1.3 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 KEP62002.1 - 7e-12 44.7 38.5 6.8e-06 25.0 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Utp14 PF04615.8 KEP62003.1 - 1.9e-75 254.5 58.8 1.9e-75 254.5 40.8 3.0 1 1 1 2 2 2 1 Utp14 protein Glucan_synthase PF02364.10 KEP62003.1 - 2.2 6.0 2.6 4 5.1 1.8 1.4 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Nop PF01798.13 KEP62004.1 - 1.1e-52 177.2 1.6 2.6e-52 176.1 1.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KEP62004.1 - 7e-28 96.2 0.6 1.2e-27 95.4 0.1 1.7 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KEP62004.1 - 3.6e-20 71.8 0.9 8.4e-20 70.6 0.7 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain MFS_1 PF07690.11 KEP62005.1 - 5.5e-07 28.6 9.7 5.5e-07 28.6 6.7 3.1 2 1 1 3 3 3 1 Major Facilitator Superfamily YqhR PF11085.3 KEP62005.1 - 0.23 10.9 2.9 0.43 10.0 2.0 1.4 1 0 0 1 1 1 0 Conserved membrane protein YqhR SPC12 PF06645.8 KEP62005.1 - 6.4 6.6 5.7 2.6 7.9 0.9 2.5 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DEAD PF00270.24 KEP62006.1 - 2.4e-27 95.4 0.0 5.3e-14 52.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62006.1 - 7.8e-20 70.5 0.0 2e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEP62006.1 - 7.7e-18 63.7 0.3 1.6e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KEP62006.1 - 0.037 13.8 0.0 12 5.6 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KEP62006.1 - 0.054 12.7 0.1 4.5 6.4 0.2 2.6 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_22 PF13401.1 KEP62006.1 - 0.06 13.4 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Nucleocapsid-N PF11030.3 KEP62006.1 - 0.2 11.4 2.2 0.42 10.3 1.5 1.5 1 0 0 1 1 1 0 Nucleocapsid protein N Pkinase PF00069.20 KEP62007.1 - 1.3e-37 129.3 0.0 7.9e-22 77.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP62007.1 - 3e-15 55.9 0.0 6.1e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP62007.1 - 4e-09 35.8 0.0 1.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KEP62007.1 - 0.0073 16.0 2.4 0.013 15.2 0.3 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEP62007.1 - 0.11 11.6 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAC PF01849.13 KEP62008.1 - 2e-18 65.6 0.1 3.6e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 KEP62008.1 - 0.00023 20.8 0.2 0.00048 19.8 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain N6_N4_Mtase PF01555.13 KEP62009.1 - 4.8 6.5 0.0 8.8 5.7 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Bac_surface_Ag PF01103.18 KEP62010.1 - 2.5e-10 40.3 0.3 1.1e-07 31.6 0.0 3.0 2 1 0 2 2 2 2 Surface antigen DUF3437 PF11919.3 KEP62012.1 - 0.89 9.3 4.2 0.6 9.8 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) Hydantoinase_B PF02538.9 KEP62012.1 - 1.1 7.3 5.7 0.51 8.5 2.4 1.5 1 1 0 1 1 1 0 Hydantoinase B/oxoprolinase Endonuc-BglII PF09195.6 KEP62012.1 - 3.4 7.1 9.0 0.64 9.4 1.3 2.4 1 1 1 2 2 2 0 Restriction endonuclease BglII Herpes_gE PF02480.11 KEP62013.1 - 0.02 13.1 0.9 0.027 12.7 0.2 1.5 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E RPN7 PF10602.4 KEP62014.1 - 0.00035 19.9 0.0 0.0026 17.1 0.0 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 KEP62014.1 - 0.0025 18.0 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 PCI domain FUSC_2 PF13515.1 KEP62015.1 - 0.041 13.8 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like HEM4 PF02602.10 KEP62016.1 - 5.4e-06 25.8 0.9 0.011 14.9 0.1 4.4 5 1 0 5 5 5 2 Uroporphyrinogen-III synthase HemD TruD PF01142.13 KEP62017.1 - 5.5e-36 124.0 0.1 8.2e-13 47.7 0.0 5.0 5 0 0 5 5 5 4 tRNA pseudouridine synthase D (TruD) ORC5_C PF14630.1 KEP62017.1 - 0.35 10.2 0.1 0.82 9.0 0.0 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus APG6 PF04111.7 KEP62018.1 - 0.005 15.9 15.8 0.005 15.9 10.9 6.3 2 1 4 6 6 6 4 Autophagy protein Apg6 AAA_13 PF13166.1 KEP62018.1 - 0.04 12.3 103.4 0.016 13.7 18.4 4.8 1 1 4 5 5 5 0 AAA domain DUF4551 PF15087.1 KEP62019.1 - 2.8 6.2 8.1 6.6 4.9 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DEAD PF00270.24 KEP62020.1 - 9.2e-32 109.8 0.0 1.8e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62020.1 - 1.7e-20 72.6 0.0 3.9e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP62020.1 - 6e-07 29.4 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KEP62020.1 - 0.0025 17.4 0.0 0.0025 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.18 KEP62020.1 - 0.004 15.9 0.1 0.021 13.6 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_19 PF13245.1 KEP62020.1 - 0.011 15.4 0.0 0.044 13.5 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KEP62020.1 - 0.066 13.3 0.2 0.49 10.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain Dna2 PF08696.6 KEP62022.1 - 5.3 6.2 0.1 11 5.2 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 Bud13 PF09736.4 KEP62023.1 - 9.4e-41 139.4 6.1 9.4e-41 139.4 4.2 2.3 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF905 PF06006.7 KEP62023.1 - 0.019 14.3 0.3 0.059 12.7 0.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Myb_DNA-binding PF00249.26 KEP62024.1 - 9e-23 80.0 0.8 1.2e-08 34.8 0.0 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEP62024.1 - 6e-19 67.9 0.0 3.6e-06 26.9 0.1 3.8 2 1 2 4 4 4 3 Myb-like DNA-binding domain Adeno_terminal PF02459.10 KEP62024.1 - 0.43 8.6 1.0 0.66 8.0 0.7 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RF-1 PF00472.15 KEP62025.1 - 5.6e-12 45.4 1.5 1.1e-11 44.5 1.0 1.5 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 KEP62025.1 - 0.0011 19.0 0.4 0.0017 18.4 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF4570 PF15134.1 KEP62026.1 - 0.0071 16.1 4.7 0.0085 15.9 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) IpaC_SipC PF09599.5 KEP62026.1 - 0.017 14.1 4.8 0.017 14.1 3.4 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) RRF PF01765.14 KEP62026.1 - 0.07 12.5 6.0 0.081 12.3 4.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF2229 PF09989.4 KEP62026.1 - 0.52 9.7 3.2 0.52 9.7 2.2 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2570 PF10828.3 KEP62026.1 - 0.55 9.8 5.1 0.64 9.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) APG6 PF04111.7 KEP62026.1 - 0.73 8.8 4.5 0.76 8.7 3.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TBCA PF02970.11 KEP62026.1 - 1 9.4 8.3 1.5 8.9 5.8 1.3 1 1 0 1 1 1 0 Tubulin binding cofactor A ATP-synt_B PF00430.13 KEP62026.1 - 1.8 8.3 11.4 2.3 8.0 7.9 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF390 PF04094.9 KEP62026.1 - 5.7 4.8 10.5 5.5 4.9 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Macoilin PF09726.4 KEP62026.1 - 9.6 4.3 9.5 9.4 4.3 6.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Gryzun PF07919.7 KEP62027.1 - 8.2e-07 27.7 0.0 1.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KEP62027.1 - 0.067 12.6 1.6 1.1 8.7 0.0 2.7 3 1 0 3 3 3 0 Foie gras liver health family 1 Glyco_hydro_100 PF12899.2 KEP62027.1 - 0.6 8.4 0.1 0.99 7.7 0.1 1.2 1 0 0 1 1 1 0 Alkaline and neutral invertase Aa_trans PF01490.13 KEP62027.1 - 6.7 5.0 0.8 10 4.4 0.5 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein PP-binding PF00550.20 KEP62028.1 - 9.7e-13 48.1 0.2 1.4e-12 47.6 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KEP62028.1 - 0.00021 21.2 0.1 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 KEP62028.1 - 0.00039 20.3 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S DUF1493 PF07377.7 KEP62028.1 - 0.0025 17.9 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) LCCL PF03815.14 KEP62030.1 - 5.1e-24 84.0 0.3 1.7e-23 82.4 0.2 2.0 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.20 KEP62030.1 - 7e-14 51.7 0.0 2e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain DUF1080 PF06439.6 KEP62030.1 - 4.3e-06 26.7 0.0 0.094 12.6 0.0 2.6 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1080) PQQ_2 PF13360.1 KEP62030.1 - 0.01 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain Fibrinogen_C PF00147.13 KEP62030.1 - 0.014 14.9 0.1 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 Fibrinogen beta and gamma chains, C-terminal globular domain SH3_3 PF08239.6 KEP62030.1 - 0.068 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain PCI PF01399.22 KEP62031.1 - 7.3e-10 39.1 0.1 4.8e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.1 KEP62031.1 - 0.037 14.6 0.0 0.15 12.7 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP62031.1 - 0.04 13.5 0.2 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP62031.1 - 0.064 13.2 0.2 0.22 11.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62031.1 - 0.069 12.9 0.1 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat UQ_con PF00179.21 KEP62032.1 - 1.6e-18 66.4 0.0 2.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.6 KEP62032.1 - 0.053 12.9 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Aminotran_1_2 PF00155.16 KEP62034.1 - 6.4e-42 143.8 0.0 9.3e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Bromodomain PF00439.20 KEP62035.1 - 3.4e-06 26.8 0.0 5.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain XRCC4 PF06632.7 KEP62035.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF1777 PF08648.7 KEP62036.1 - 9.3e-19 67.8 62.2 1.2e-18 67.5 41.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) KIAA1328 PF15369.1 KEP62036.1 - 2.7 7.7 9.4 3.6 7.3 6.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Aldedh PF00171.17 KEP62037.1 - 3.8e-10 38.6 1.3 8.3e-05 21.0 0.0 3.1 3 0 0 3 3 3 3 Aldehyde dehydrogenase family DUF2292 PF10055.4 KEP62037.1 - 0.14 11.5 0.0 0.4 10.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) PPR_2 PF13041.1 KEP62039.1 - 3.9e-38 129.1 0.4 8.2e-13 48.1 0.0 8.3 5 3 4 9 9 9 5 PPR repeat family PPR PF01535.15 KEP62039.1 - 9.5e-22 75.4 3.0 0.008 16.0 0.0 9.8 10 0 0 10 10 10 4 PPR repeat PPR_3 PF13812.1 KEP62039.1 - 1.3e-19 68.7 21.9 0.0016 18.5 0.0 9.4 11 0 0 11 11 11 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 KEP62039.1 - 4.3e-19 67.6 1.4 0.00015 21.1 0.0 8.3 9 0 0 9 9 9 4 PPR repeat CAF-1_p150 PF11600.3 KEP62039.1 - 0.0037 16.6 0.5 0.0037 16.6 0.3 11.8 10 3 0 10 10 10 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal ATP13 PF12921.2 KEP62039.1 - 0.18 11.1 0.0 0.77 9.1 0.0 2.1 1 1 0 1 1 1 0 Mitochondrial ATPase expression tRNA-synt_1c PF00749.16 KEP62040.1 - 1.5e-101 339.2 0.0 2e-101 338.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEP62040.1 - 9.4e-38 129.5 0.0 1.1e-36 126.1 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 KEP62040.1 - 1.2e-06 28.9 0.0 1e-05 25.9 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEP62040.1 - 6.6e-05 22.8 0.0 0.00056 19.8 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEP62040.1 - 0.00024 20.9 0.2 0.0013 18.5 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Hep_59 PF07052.6 KEP62041.1 - 6.9e-21 74.5 0.2 6.9e-21 74.5 0.1 3.5 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 TPR_20 PF14561.1 KEP62043.1 - 0.15 12.1 3.2 0.79 9.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.24 KEP62044.1 - 2.7e-37 127.8 0.0 6.5e-37 126.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62044.1 - 4.2e-26 90.6 0.2 1.1e-25 89.2 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNase_P_p30 PF01876.11 KEP62046.1 - 4.5e-16 58.4 0.0 2.1e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RNase P subunit p30 CTP_transf_1 PF01148.15 KEP62047.1 - 1.6e-39 136.1 0.1 2.3e-38 132.3 0.1 2.4 1 1 0 1 1 1 1 Cytidylyltransferase family ABC_tran PF00005.22 KEP62050.1 - 5.5e-25 88.2 0.0 8.7e-24 84.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KEP62050.1 - 2.9e-21 76.0 5.3 1e-19 71.0 1.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.1 KEP62050.1 - 0.0053 16.7 0.4 0.0053 16.7 0.3 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KEP62050.1 - 0.0074 15.7 0.1 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KEP62050.1 - 0.0098 15.7 0.1 0.15 12.0 0.1 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KEP62050.1 - 0.011 15.7 0.0 2.3 8.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF87 PF01935.12 KEP62050.1 - 0.029 14.2 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_17 PF13207.1 KEP62050.1 - 0.037 14.8 0.0 0.066 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEP62050.1 - 0.086 12.9 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DAO PF01266.19 KEP62051.1 - 2.7e-37 128.5 0.1 3.8e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEP62051.1 - 2.2e-09 36.6 1.6 0.00012 21.0 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 KEP62051.1 - 4.8e-06 25.8 0.2 0.0058 15.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KEP62051.1 - 4.5e-05 22.7 0.3 0.0003 19.9 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEP62051.1 - 0.0068 16.2 0.0 0.078 12.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEP62051.1 - 0.059 12.2 0.1 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KEP62051.1 - 0.12 12.3 1.0 0.56 10.2 0.6 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 KEP62052.1 - 9.7e-22 77.0 2.1 1.6e-21 76.3 1.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEP62052.1 - 8.6e-15 54.8 2.4 1.5e-14 54.0 1.7 1.4 1 0 0 1 1 1 1 HMG-box domain Globin PF00042.17 KEP62052.1 - 0.024 14.9 0.0 0.029 14.6 0.0 1.1 1 0 0 1 1 1 0 Globin HMG_box_5 PF14887.1 KEP62052.1 - 0.074 12.8 2.4 0.068 12.9 0.8 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box 5 MBOAT PF03062.14 KEP62053.1 - 1.5e-23 83.4 22.3 1.5e-23 83.4 15.5 2.2 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KEP62053.1 - 0.00056 19.9 3.8 0.00056 19.9 2.6 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family BioY PF02632.9 KEP62053.1 - 0.0064 16.1 0.8 0.0064 16.1 0.6 3.2 3 1 0 3 3 3 1 BioY family Ribosomal_S11 PF00411.14 KEP62055.1 - 2.2e-42 143.7 0.4 2.7e-42 143.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 KEP62055.1 - 0.071 11.9 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF814 PF05670.8 KEP62055.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) DIE2_ALG10 PF04922.7 KEP62056.1 - 7.9e-43 146.9 16.0 3e-19 69.3 0.2 5.3 5 1 0 5 5 5 4 DIE2/ALG10 family FtsJ PF01728.14 KEP62058.1 - 2.2e-61 207.0 0.0 3.9e-61 206.2 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 KEP62058.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 KEP62058.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RINT1_TIP1 PF04437.8 KEP62058.1 - 0.061 11.8 0.5 0.088 11.3 0.4 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family CENP-B_dimeris PF09026.5 KEP62058.1 - 0.22 11.7 7.8 0.26 11.5 2.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KEP62058.1 - 2.2 7.7 9.1 1.7 8.1 4.9 1.7 2 0 0 2 2 2 0 Nucleoplasmin DUF4632 PF15451.1 KEP62058.1 - 7.1 6.6 8.7 5.5 6.9 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) COPI_assoc PF08507.5 KEP62059.1 - 0.0077 15.9 1.8 0.011 15.4 1.3 1.2 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 KEP62059.1 - 0.049 13.6 2.6 0.098 12.6 1.8 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF4231 PF14015.1 KEP62059.1 - 0.074 13.0 0.1 0.99 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1622 PF07784.6 KEP62059.1 - 0.11 12.1 0.4 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) OB_NTP_bind PF07717.11 KEP62061.1 - 1.9e-28 98.5 0.0 4.9e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEP62061.1 - 9.2e-28 96.2 0.0 3.4e-27 94.4 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEP62061.1 - 1.6e-11 43.8 0.0 3.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP62061.1 - 0.00011 21.8 0.0 0.00028 20.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEP62061.1 - 0.00017 21.7 0.0 0.00075 19.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KEP62061.1 - 0.00071 18.5 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MIP-T3 PF10243.4 KEP62062.1 - 2.9 6.2 19.1 5.2 5.4 13.3 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GRP PF07172.6 KEP62064.1 - 0.043 14.2 5.1 0.055 13.9 3.5 1.2 1 0 0 1 1 1 0 Glycine rich protein family CDC27 PF09507.5 KEP62065.1 - 0.11 11.7 43.6 0.14 11.3 30.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.7 KEP62067.1 - 7e-05 22.2 28.4 0.00011 21.5 19.7 1.4 1 0 0 1 1 1 1 SDA1 Ycf1 PF05758.7 KEP62067.1 - 7.4e-05 20.6 11.5 7.7e-05 20.6 8.0 1.1 1 0 0 1 1 1 1 Ycf1 Nop14 PF04147.7 KEP62067.1 - 0.0051 14.8 41.4 0.0078 14.1 28.7 1.2 1 0 0 1 1 1 1 Nop14-like family Paf1 PF03985.8 KEP62067.1 - 0.015 14.0 30.8 0.023 13.4 21.4 1.3 1 0 0 1 1 1 0 Paf1 Plasmodium_Vir PF05795.6 KEP62067.1 - 0.018 14.2 5.2 0.028 13.6 3.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TFIIF_alpha PF05793.7 KEP62067.1 - 0.023 13.0 35.3 0.032 12.6 24.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 KEP62067.1 - 0.025 13.2 10.1 0.026 13.1 7.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 KEP62067.1 - 0.078 11.4 38.1 0.1 11.0 26.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 KEP62067.1 - 0.27 10.3 13.3 0.53 9.4 9.2 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Pox_Ag35 PF03286.9 KEP62067.1 - 0.41 10.1 21.4 1.2 8.5 14.9 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DARPP-32 PF05395.7 KEP62067.1 - 0.43 10.7 26.1 0.057 13.5 15.0 1.7 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 DUF1510 PF07423.6 KEP62067.1 - 0.43 9.8 34.3 0.85 8.9 23.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 KEP62067.1 - 0.51 8.7 47.6 0.96 7.8 33.0 1.4 1 1 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 KEP62067.1 - 1 9.1 30.1 0.13 12.1 17.8 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.7 KEP62067.1 - 1.5 7.1 37.6 2.3 6.4 26.1 1.2 1 0 0 1 1 1 0 Mpp10 protein CT47 PF15623.1 KEP62067.1 - 2.1 8.0 38.6 4.3 6.9 26.7 1.5 1 0 0 1 1 1 0 Cancer/testis gene family 47 Hid1 PF12722.2 KEP62067.1 - 2.3 5.7 12.2 3.1 5.3 8.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.6 KEP62067.1 - 2.6 6.1 15.6 2.6 6.2 10.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF-3c_N PF05470.7 KEP62067.1 - 2.7 5.9 18.5 3.5 5.6 12.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC27 PF09507.5 KEP62067.1 - 3.9 6.5 30.5 6.9 5.7 21.1 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2413 PF10310.4 KEP62067.1 - 5.7 5.6 22.9 8.4 5.0 15.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Zip PF02535.17 KEP62067.1 - 6.2 5.7 11.4 13 4.6 7.9 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter SprA-related PF12118.3 KEP62067.1 - 6.4 6.0 25.6 0.68 9.2 14.4 1.7 2 0 0 2 2 2 0 SprA-related family Peptidase_S64 PF08192.6 KEP62067.1 - 7.3 4.7 9.4 8.6 4.5 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 RRM_1 PF00076.17 KEP62069.1 - 2.5e-13 49.4 0.0 5e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62069.1 - 5.1e-08 32.7 0.0 9.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62069.1 - 4.7e-05 23.1 0.0 8.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Orbi_NS1 PF01718.11 KEP62069.1 - 0.13 10.2 4.4 0.22 9.5 3.1 1.3 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein DUF572 PF04502.8 KEP62069.1 - 2.9 7.0 29.7 4.3 6.4 20.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ank_2 PF12796.2 KEP62071.1 - 9e-25 86.8 0.7 1.6e-13 50.7 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEP62071.1 - 9.2e-22 75.7 0.5 3.5e-06 26.5 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Bromodomain PF00439.20 KEP62071.1 - 1.1e-20 73.3 0.0 2.7e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 Bromodomain Ank_4 PF13637.1 KEP62071.1 - 2.7e-16 59.6 1.9 7.9e-07 29.4 0.0 3.9 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP62071.1 - 3.5e-16 57.6 0.0 0.00021 21.1 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 KEP62071.1 - 4.2e-14 52.2 0.3 2.7e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF3510 PF12022.3 KEP62071.1 - 0.023 14.7 0.2 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) MSA-2c PF12238.3 KEP62071.1 - 0.17 11.4 6.8 0.052 13.2 2.2 1.9 1 1 1 2 2 2 0 Merozoite surface antigen 2c SRP-alpha_N PF04086.8 KEP62071.1 - 0.4 10.0 13.9 0.72 9.1 9.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Baculo_PEP_C PF04513.7 KEP62072.1 - 0.67 9.7 6.3 7.6 6.3 0.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MRP-L47 PF06984.8 KEP62074.1 - 1.9e-27 94.9 0.4 1.9e-27 94.9 0.3 2.3 2 1 1 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2750 PF11042.3 KEP62074.1 - 0.015 15.3 0.2 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) V_ATPase_I PF01496.14 KEP62074.1 - 1.1 6.9 4.8 1.3 6.7 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cpn10 PF00166.16 KEP62076.1 - 1.6e-24 85.6 0.1 1.9e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit STOP PF05217.7 KEP62077.1 - 5.9e-37 127.4 0.5 5.9e-37 127.4 0.4 2.0 2 1 0 2 2 2 1 STOP protein Spc97_Spc98 PF04130.8 KEP62078.1 - 9e-51 172.7 0.0 1.3e-50 172.2 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Vps26 PF03643.10 KEP62079.1 - 1.2e-106 355.4 3.0 1.5e-106 355.2 2.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KEP62079.1 - 0.023 14.5 1.4 26 4.6 0.0 3.7 2 2 1 4 4 4 0 Arrestin (or S-antigen), N-terminal domain UQ_con PF00179.21 KEP62080.1 - 1.4e-44 150.9 0.0 1.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEP62080.1 - 0.0024 17.6 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEP62080.1 - 0.0066 16.3 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain Na_H_Exchanger PF00999.16 KEP62081.1 - 6.5e-46 156.5 34.4 6.5e-46 156.5 23.9 1.6 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family GWT1 PF06423.7 KEP62081.1 - 0.013 15.5 1.4 0.041 13.9 0.9 1.9 1 0 0 1 1 1 0 GWT1 UPF0154 PF03672.8 KEP62081.1 - 1.1 8.9 2.9 4.1 7.1 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Peptidase_C12 PF01088.16 KEP62082.1 - 3.8e-56 189.6 0.0 6.3e-53 179.1 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 La PF05383.12 KEP62083.1 - 1.9e-06 27.5 0.0 0.0026 17.4 0.0 2.3 2 0 0 2 2 2 2 La domain Nop53 PF07767.6 KEP62084.1 - 6.9e-23 81.2 47.6 7.8e-13 48.1 13.4 3.2 1 1 1 3 3 3 3 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.7 KEP62084.1 - 0.00076 19.2 0.2 0.00076 19.2 0.2 3.0 3 0 0 3 3 3 1 BOP1NT (NUC169) domain NAD_binding_2 PF03446.10 KEP62085.1 - 3.1e-51 173.4 0.2 4.3e-51 172.9 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KEP62085.1 - 3.4e-34 117.5 0.6 8.2e-34 116.2 0.4 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KEP62085.1 - 6.3e-11 42.5 0.1 2.1e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KEP62085.1 - 2.2e-08 34.2 0.0 5.4e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KEP62085.1 - 6.1e-06 25.4 0.0 9.7e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KEP62085.1 - 0.00014 21.5 0.2 0.00026 20.7 0.1 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 KEP62085.1 - 0.0045 16.3 0.0 0.0099 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 KEP62085.1 - 0.026 14.7 0.1 0.2 11.9 0.0 2.3 1 1 1 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KEP62085.1 - 0.034 14.1 0.2 0.05 13.5 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KEP62085.1 - 0.04 13.2 0.2 4.7 6.5 0.0 2.3 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UCH PF00443.24 KEP62086.1 - 2e-69 233.6 0.0 5.6e-69 232.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP62086.1 - 4.1e-19 69.1 0.0 1.4e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KEP62086.1 - 3.3e-05 24.1 0.0 0.00012 22.3 0.0 2.0 2 0 0 2 2 2 1 DUSP domain LCCL PF03815.14 KEP62087.1 - 6.1e-105 343.4 3.8 6.1e-26 90.2 0.1 4.5 4 0 0 4 4 4 4 LCCL domain SRCR PF00530.13 KEP62087.1 - 2e-33 114.6 10.0 6.6e-17 61.6 0.7 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain PLAT PF01477.18 KEP62087.1 - 8.3e-18 64.8 0.0 3.9e-11 43.3 0.0 3.0 3 0 0 3 3 3 2 PLAT/LH2 domain Laminin_G_3 PF13385.1 KEP62087.1 - 5.1e-17 62.5 0.1 3.5e-16 59.8 0.0 2.4 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Rxt3 PF08642.5 KEP62087.1 - 3.3e-08 33.7 0.0 0.041 14.1 0.0 4.2 4 0 0 4 4 4 2 Histone deacetylation protein Rxt3 SRCR_2 PF15494.1 KEP62087.1 - 1.1e-06 28.7 2.5 0.0004 20.5 0.4 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Pentaxin PF00354.12 KEP62087.1 - 2.5e-05 23.7 0.0 8.9e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Pentaxin family Sialidase PF02973.11 KEP62087.1 - 0.017 14.0 0.1 0.049 12.6 0.0 1.7 2 0 0 2 2 2 0 Sialidase, N-terminal domain PseudoU_synth_2 PF00849.17 KEP62088.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA pseudouridylate synthase ORC5_C PF14630.1 KEP62089.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus NIF PF03031.13 KEP62090.1 - 6.4e-48 162.4 0.2 8e-48 162.1 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.27 KEP62091.1 - 8.6e-17 60.3 13.0 1.9e-05 24.3 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nbas_N PF15492.1 KEP62091.1 - 0.0027 16.8 0.0 2.3 7.2 0.0 2.7 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.1 KEP62091.1 - 0.016 14.9 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Med16 PF11635.3 KEP62091.1 - 0.028 12.3 0.0 0.11 10.4 0.0 1.7 1 1 1 2 2 2 0 Mediator complex subunit 16 Tetraspannin PF00335.15 KEP62092.1 - 0.00031 20.0 16.2 0.83 8.8 12.5 2.4 2 1 0 2 2 2 2 Tetraspanin family CD34_antigen PF06365.7 KEP62092.1 - 0.076 12.6 0.9 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF3367 PF11847.3 KEP62092.1 - 0.14 10.0 1.4 0.22 9.4 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) DUF1345 PF07077.6 KEP62092.1 - 0.58 9.6 4.1 1.4 8.3 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Anoctamin PF04547.7 KEP62092.1 - 1.6 7.2 4.2 0.77 8.3 0.0 1.9 1 1 0 2 2 2 0 Calcium-activated chloride channel GPI2 PF06432.6 KEP62092.1 - 8.1 5.6 8.8 2 7.6 3.8 1.5 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase SpoU_methylase PF00588.14 KEP62093.1 - 1.8e-18 66.8 0.0 5.1e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF1681 PF07933.9 KEP62095.1 - 1.5e-42 144.9 0.0 1.9e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Fis1_TPR_C PF14853.1 KEP62097.1 - 2.3e-19 69.0 0.0 4.8e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KEP62097.1 - 1.2e-08 34.1 0.0 2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_11 PF13414.1 KEP62097.1 - 9.1e-05 22.0 0.0 0.00026 20.5 0.0 1.7 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEP62097.1 - 0.00087 19.0 0.0 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62097.1 - 0.04 14.5 0.3 0.13 12.9 0.0 1.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEP62097.1 - 0.068 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62097.1 - 0.071 13.7 0.3 1.3 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Neuropep_like PF15161.1 KEP62097.1 - 0.17 11.3 0.4 0.5 9.8 0.1 1.8 2 0 0 2 2 2 0 Neuropeptide-like Cir_N PF10197.4 KEP62099.1 - 2.1e-10 40.4 10.1 2.1e-10 40.4 7.0 4.0 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR PAPA-1 PF04795.7 KEP62099.1 - 1.5 9.5 20.3 0.48 11.1 6.1 3.2 3 0 0 3 3 3 0 PAPA-1-like conserved region Porin_3 PF01459.17 KEP62100.1 - 1.1e-15 57.7 1.2 1.3e-15 57.4 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rhomboid PF01694.17 KEP62101.1 - 5.7e-28 97.7 14.5 5.7e-28 97.7 10.0 1.5 2 0 0 2 2 2 1 Rhomboid family DUF3353 PF11833.3 KEP62102.1 - 0.0089 15.4 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3353) GDPD PF03009.12 KEP62103.1 - 6.3e-18 65.2 0.0 1.3e-17 64.1 0.0 1.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.11 KEP62104.1 - 3.1e-11 42.6 22.0 3.9e-10 38.9 9.8 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily CPW_WPC PF09717.5 KEP62106.1 - 2.3e-26 92.1 13.0 9.4e-15 54.9 1.3 2.2 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) MerC PF03203.9 KEP62107.1 - 2.8e-13 50.2 11.9 4.7e-13 49.5 8.2 1.3 1 0 0 1 1 1 1 MerC mercury resistance protein DUF4131 PF13567.1 KEP62107.1 - 0.063 12.6 1.0 0.12 11.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) 2TM PF13239.1 KEP62107.1 - 0.65 10.0 6.3 0.19 11.8 1.2 2.2 2 0 0 2 2 2 0 2TM domain YbhQ PF11076.3 KEP62109.1 - 1.8 8.1 4.9 0.76 9.3 0.6 2.3 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Pkinase PF00069.20 KEP62110.1 - 4.6e-28 98.0 0.0 7e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEP62110.1 - 9.9e-18 64.1 0.0 1.9e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KEP62110.1 - 1.4e-10 40.6 0.0 7.8e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase UIM PF02809.15 KEP62111.1 - 7.2e-07 28.2 15.9 0.00099 18.4 3.1 3.7 2 0 0 2 2 2 2 Ubiquitin interaction motif GAS PF13851.1 KEP62112.1 - 0.0016 17.6 39.6 0.056 12.6 1.9 3.5 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Vps51 PF08700.6 KEP62112.1 - 0.0063 16.3 2.2 0.0063 16.3 1.5 3.2 2 2 1 3 3 3 1 Vps51/Vps67 Prefoldin PF02996.12 KEP62112.1 - 0.028 14.0 12.1 0.1 12.2 0.3 3.6 3 0 0 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 KEP62112.1 - 1.2 9.2 17.1 4.7 7.3 0.6 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 KEP62112.1 - 1.8 8.3 35.6 0.71 9.6 1.2 3.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Lyase_1 PF00206.15 KEP62113.1 - 2.7e-51 174.6 0.0 4.9e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 KEP62113.1 - 6.9e-42 141.9 0.7 1.6e-41 140.7 0.1 1.9 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal Arc_PepC PF06819.6 KEP62113.1 - 0.0081 16.0 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Archaeal Peptidase A24 C-terminal Domain Myosin_head PF00063.16 KEP62114.1 - 8.7e-168 559.4 0.0 1.3e-167 558.9 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Zeta_toxin PF06414.7 KEP62114.1 - 0.00026 20.1 0.2 0.00049 19.2 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 KEP62114.1 - 0.027 14.4 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KEP62114.1 - 0.032 14.3 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEP62114.1 - 0.047 14.5 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEP62114.1 - 0.07 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 KEP62114.1 - 0.071 12.7 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KEP62114.1 - 0.1 12.8 0.1 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 KEP62114.1 - 0.12 12.5 0.1 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase CS PF04969.11 KEP62115.1 - 1.5e-08 35.0 0.0 2.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_19 PF14559.1 KEP62117.1 - 2.2e-08 34.3 2.1 2.9e-06 27.5 0.0 5.2 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEP62117.1 - 8.2e-08 31.7 1.8 0.0015 18.1 0.0 4.0 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 KEP62117.1 - 6.8e-07 28.7 5.1 0.019 14.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP62117.1 - 1e-06 28.4 0.0 0.85 9.9 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEP62117.1 - 6.2e-05 22.4 0.1 0.029 13.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62117.1 - 0.00041 20.7 26.2 0.0073 16.8 0.1 6.6 6 1 2 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62117.1 - 0.00066 20.2 32.1 0.0034 18.0 0.0 5.6 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEP62117.1 - 0.0018 18.1 15.1 0.091 12.7 0.0 5.1 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62117.1 - 0.0023 17.5 0.0 1.2 9.0 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEP62117.1 - 0.032 14.0 0.0 0.032 14.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEP62117.1 - 0.07 13.0 0.3 16 5.5 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KEP62117.1 - 0.24 11.2 11.3 5.3 7.0 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP62117.1 - 1.3 9.6 0.0 1.3 9.6 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat SNF2_N PF00176.18 KEP62118.1 - 2.5e-62 210.3 0.0 3.6e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP62118.1 - 5.1e-13 48.6 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP62118.1 - 3.3e-05 23.4 0.0 6.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KEP62118.1 - 0.015 14.0 0.0 0.12 11.1 0.0 2.1 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Citrate_synt PF00285.16 KEP62120.1 - 9.2e-116 386.4 0.0 1.1e-115 386.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase PP-binding_2 PF14573.1 KEP62121.1 - 9.7e-12 44.7 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-carrier RRM_1 PF00076.17 KEP62122.1 - 2.7e-31 107.0 2.4 4.4e-17 61.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62122.1 - 3.2e-31 107.1 0.5 1e-14 54.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62122.1 - 1.6e-13 50.2 1.2 4.5e-06 26.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEP62122.1 - 5.7e-06 26.1 0.9 0.025 14.4 0.1 2.4 1 1 1 2 2 2 2 RNA binding motif Hum_adeno_E3A PF05393.6 KEP62123.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein zf-ribbon_3 PF13248.1 KEP62124.1 - 0.00065 18.8 4.8 0.0013 17.8 3.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 KEP62124.1 - 0.0018 18.0 0.9 0.0031 17.2 0.6 1.4 1 0 0 1 1 1 1 Double zinc ribbon Glutaredoxin PF00462.19 KEP62124.1 - 2.5 8.1 8.9 0.86 9.6 0.3 3.8 2 2 0 2 2 2 0 Glutaredoxin Voltage_CLC PF00654.15 KEP62125.1 - 5.9e-61 206.4 35.4 1.7e-22 79.9 6.7 4.1 4 0 0 4 4 4 3 Voltage gated chloride channel CBS PF00571.23 KEP62125.1 - 1.4e-05 24.7 0.0 0.096 12.4 0.1 2.6 2 0 0 2 2 2 2 CBS domain CENP-F_leu_zip PF10473.4 KEP62128.1 - 0.21 11.4 39.0 0.07 12.9 14.5 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KEP62128.1 - 3.4 6.7 8.8 0.72 8.9 1.1 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Hexokinase_1 PF00349.16 KEP62129.1 - 6.5e-54 182.3 0.0 9.2e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KEP62129.1 - 7.5e-49 166.1 0.4 1.2e-48 165.4 0.3 1.3 1 0 0 1 1 1 1 Hexokinase PPP4R2 PF09184.6 KEP62130.1 - 2e-09 37.4 0.2 2e-09 37.4 0.1 4.7 2 1 1 4 4 4 1 PPP4R2 GPDPase_memb PF10110.4 KEP62131.1 - 0.03 13.7 0.5 0.094 12.1 0.0 1.9 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase ATG16 PF08614.6 KEP62132.1 - 0.00029 20.7 3.9 0.00029 20.7 2.7 2.5 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 KEP62132.1 - 0.0067 16.2 7.0 0.0067 16.2 4.8 1.8 2 0 0 2 2 2 1 Tropomyosin like Mnd1 PF03962.10 KEP62132.1 - 0.042 13.4 9.8 0.014 15.1 4.7 1.6 2 0 0 2 2 2 0 Mnd1 family V_ATPase_I PF01496.14 KEP62132.1 - 0.076 10.8 1.8 0.073 10.9 1.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 KEP62132.1 - 0.13 12.3 4.1 0.19 11.7 2.8 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein TMF_DNA_bd PF12329.3 KEP62132.1 - 0.13 12.0 17.1 0.17 11.6 2.4 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 KEP62132.1 - 0.31 10.0 10.1 0.046 12.7 4.3 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 PEP-utilisers_N PF05524.8 KEP62132.1 - 0.38 10.5 4.5 0.19 11.5 1.6 1.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Atg14 PF10186.4 KEP62132.1 - 0.73 8.7 9.5 0.43 9.4 4.8 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 KEP62132.1 - 1.9 8.2 11.5 0.58 9.8 5.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CRF PF00473.12 KEP62132.1 - 2.8 8.0 4.9 20 5.3 0.2 2.6 2 0 0 2 2 2 0 Corticotropin-releasing factor family Fib_alpha PF08702.5 KEP62132.1 - 3.6 7.7 6.5 7.9 6.5 0.3 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 KEP62132.1 - 7.7 6.0 12.2 4 6.9 1.0 2.8 2 1 1 3 3 3 0 Septum formation initiator WD40 PF00400.27 KEP62133.1 - 8.5e-41 136.4 10.9 4.6e-09 35.8 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 KEP62133.1 - 7.4e-05 22.5 0.6 0.79 9.3 0.0 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 KEP62133.1 - 0.012 15.0 0.1 0.096 12.1 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain DUF2439 PF10382.4 KEP62133.1 - 0.1 12.8 0.1 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) Nup160 PF11715.3 KEP62133.1 - 3.1 5.8 6.0 0.45 8.5 0.4 2.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Paf1 PF03985.8 KEP62135.1 - 1 7.9 4.5 1 8.0 3.1 1.0 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 KEP62135.1 - 1.1 8.3 6.2 1 8.4 4.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4637 PF15470.1 KEP62135.1 - 6.8 6.2 7.6 7.9 6.0 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BMF PF15185.1 KEP62135.1 - 7.8 5.7 7.4 9.8 5.4 5.1 1.3 1 1 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DNA_pol_phi PF04931.8 KEP62135.1 - 9 3.9 11.8 10 3.7 8.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi CLTH PF10607.4 KEP62136.1 - 6.3e-17 61.6 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KEP62136.1 - 0.0002 20.9 0.1 0.00061 19.4 0.0 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Latarcin PF10279.4 KEP62136.1 - 0.0028 17.8 1.9 0.075 13.2 0.0 2.3 2 0 0 2 2 2 1 Latarcin precursor Fzo_mitofusin PF04799.8 KEP62136.1 - 0.35 10.2 1.7 0.8 9.0 0.2 1.9 2 0 0 2 2 2 0 fzo-like conserved region U-box PF04564.10 KEP62137.1 - 1.6e-21 75.9 0.0 2.8e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KEP62137.1 - 2.9e-19 68.4 1.8 4e-15 55.2 0.3 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEP62137.1 - 4.6e-14 51.3 3.6 3.3e-06 26.4 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP62137.1 - 1.1e-09 37.4 6.0 0.00017 21.2 0.1 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP62137.1 - 1.8e-08 33.9 0.4 0.028 14.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KEP62137.1 - 1.9e-07 31.1 1.3 4.6e-07 29.8 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEP62137.1 - 3e-07 30.2 4.0 0.0011 18.8 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62137.1 - 7.5e-06 25.3 1.0 0.29 11.0 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62137.1 - 4.5e-05 23.7 1.3 0.87 10.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEP62137.1 - 0.001 18.7 2.5 0.017 14.8 0.0 3.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP62137.1 - 0.0018 18.5 0.4 0.38 11.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62137.1 - 0.0019 18.8 0.2 0.43 11.3 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Clathrin PF00637.15 KEP62137.1 - 0.032 13.8 0.3 1.9 8.0 0.1 2.8 2 2 0 2 2 2 0 Region in Clathrin and VPS TPR_6 PF13174.1 KEP62137.1 - 0.036 14.5 2.7 23 5.7 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEP62137.1 - 0.086 12.7 0.5 3.8 7.4 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Sua5_yciO_yrdC PF01300.13 KEP62138.1 - 0.1 11.8 0.0 0.29 10.3 0.0 1.6 1 1 1 2 2 2 0 Telomere recombination 4HBT PF03061.17 KEP62139.1 - 0.011 15.8 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Thioesterase superfamily LPAM_1 PF08139.7 KEP62139.1 - 0.041 14.1 2.0 0.31 11.3 0.5 2.8 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Pkinase PF00069.20 KEP62140.1 - 3.9e-62 209.7 0.0 4.7e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP62140.1 - 3.2e-28 98.5 0.0 4.1e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP62140.1 - 4.1e-07 29.2 0.0 7.1e-06 25.1 0.0 2.3 1 1 1 3 3 3 1 Kinase-like APH PF01636.18 KEP62140.1 - 0.00084 19.1 0.2 0.0031 17.2 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEP62140.1 - 0.043 13.3 0.1 0.074 12.6 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KEP62140.1 - 0.051 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_5 PF13893.1 KEP62141.1 - 3.4e-08 33.2 0.0 7.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP62141.1 - 0.00084 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 KEP62142.1 - 1.3e-25 88.8 5.5 2.2e-25 88.1 3.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEP62142.1 - 1.3e-25 89.0 2.2 1.2e-21 76.3 0.2 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain Miro PF08477.8 KEP62147.1 - 5.9e-07 29.9 0.0 0.0023 18.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 KEP62147.1 - 7.7e-07 28.6 0.0 0.01 15.2 0.0 2.8 3 0 0 3 3 3 2 Ras family AAA_16 PF13191.1 KEP62147.1 - 0.004 17.1 0.1 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain E7 PF00527.13 KEP62147.1 - 0.013 15.6 0.5 0.099 12.8 0.0 2.6 2 0 0 2 2 2 0 E7 protein, Early protein MobB PF03205.9 KEP62147.1 - 0.027 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KEP62147.1 - 0.04 13.5 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MCM PF00493.18 KEP62147.1 - 0.094 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family Dynamin_N PF00350.18 KEP62147.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Dynamin family Septin PF00735.13 KEP62147.1 - 0.3 10.0 0.0 0.52 9.2 0.0 1.2 1 0 0 1 1 1 0 Septin RRM_6 PF14259.1 KEP62148.1 - 3.4e-07 30.1 0.0 6.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP62148.1 - 0.00014 21.4 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62148.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FUSC PF04632.7 KEP62149.1 - 4.1 5.7 5.0 6.4 5.0 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ETF_QO PF05187.8 KEP62150.1 - 2.1e-32 111.3 0.0 3.6e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 KEP62150.1 - 7.2e-06 25.9 0.0 3.5e-05 23.7 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEP62150.1 - 2.3e-05 23.4 0.0 0.00023 20.1 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEP62150.1 - 3.4e-05 22.5 0.4 5e-05 21.9 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KEP62150.1 - 7.8e-05 22.8 0.1 0.00077 19.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEP62150.1 - 7.9e-05 21.6 3.8 0.00015 20.7 1.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KEP62150.1 - 0.0002 21.3 0.1 0.00047 20.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEP62150.1 - 0.00039 19.4 0.0 0.00066 18.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEP62150.1 - 0.0009 18.3 0.0 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KEP62150.1 - 0.0024 17.0 0.4 0.0044 16.1 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEP62150.1 - 0.02 14.6 0.2 0.089 12.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 KEP62150.1 - 0.049 12.5 0.2 0.076 11.8 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KEP62150.1 - 0.27 9.7 1.3 0.38 9.3 0.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GrpE PF01025.14 KEP62151.1 - 2.1e-46 157.5 8.0 3e-46 157.0 5.6 1.2 1 0 0 1 1 1 1 GrpE DUF904 PF06005.7 KEP62151.1 - 0.0026 18.0 4.3 0.0059 16.8 3.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Herpes_UL6 PF01763.11 KEP62151.1 - 0.0095 14.1 0.6 0.014 13.6 0.4 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like ZYG-11_interact PF05884.7 KEP62151.1 - 1.4 7.9 3.8 0.35 9.9 0.4 1.5 2 0 0 2 2 2 0 Interactor of ZYG-11 WD40 PF00400.27 KEP62152.1 - 3e-21 74.4 13.9 5.7e-07 29.1 0.1 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Reo_sigmaC PF04582.7 KEP62152.1 - 0.015 14.4 0.1 0.015 14.4 0.1 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PQQ_3 PF13570.1 KEP62152.1 - 0.22 11.8 0.4 16 5.9 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain Peptidase_C48 PF02902.14 KEP62153.1 - 4.5e-23 82.0 0.0 8.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HWE_HK PF07536.9 KEP62156.1 - 0.058 13.8 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 HWE histidine kinase Ank_5 PF13857.1 KEP62157.1 - 2e-09 37.3 1.2 0.01 16.0 0.1 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEP62157.1 - 5.4e-08 33.1 0.1 0.17 12.4 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEP62157.1 - 4.2e-07 30.2 0.9 0.051 13.9 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEP62157.1 - 0.013 15.6 4.1 1.6 9.1 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat Mitofilin PF09731.4 KEP62157.1 - 0.1 11.2 10.1 0.029 13.0 3.0 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Ank PF00023.25 KEP62157.1 - 0.16 11.8 3.2 6.2 6.8 0.1 4.1 4 0 0 4 4 4 0 Ankyrin repeat Flg_hook PF02120.11 KEP62158.1 - 0.011 15.3 0.6 0.019 14.6 0.4 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF664 PF04978.7 KEP62158.1 - 0.037 14.2 0.1 0.27 11.4 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF664) DUF2795 PF11387.3 KEP62158.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) DUF663 PF04950.7 KEP62159.1 - 2.7e-76 256.4 1.2 7e-65 218.9 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF663) AARP2CN PF08142.7 KEP62159.1 - 4.3e-12 45.4 0.1 1.7e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 AARP2CN (NUC121) domain Spt5_N PF11942.3 KEP62159.1 - 0.85 10.2 21.3 1.1 9.9 13.0 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal HNH_3 PF13392.1 KEP62160.1 - 0.063 12.6 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease TTL PF03133.10 KEP62162.1 - 2.7e-29 102.0 0.0 6.6e-28 97.4 0.0 2.7 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEP62162.1 - 0.34 9.6 0.0 5 5.8 0.0 2.1 2 0 0 2 2 2 0 YheC/D like ATP-grasp DUF3661 PF12400.3 KEP62163.1 - 1.4e-27 96.2 1.3 2.2e-27 95.6 0.9 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein DUF3989 PF13150.1 KEP62163.1 - 0.059 12.8 0.5 0.14 11.6 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3989) EGF_2 PF07974.8 KEP62168.1 - 0.97 9.6 36.4 0.16 12.1 4.6 4.1 3 0 0 3 3 3 0 EGF-like domain Vps36_ESCRT-II PF11605.3 KEP62170.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AA_kinase PF00696.23 KEP62171.1 - 3.4e-32 111.9 0.2 5.6e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KEP62171.1 - 5.9e-13 48.3 0.1 4.4e-09 35.9 0.0 2.8 2 0 0 2 2 2 2 PUA domain Choline_kinase PF01633.15 KEP62172.1 - 1.9e-41 141.9 0.0 9.2e-24 84.1 0.1 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 KEP62172.1 - 4.6e-13 49.4 1.2 1.2e-06 28.4 0.0 3.0 4 0 0 4 4 4 2 Phosphotransferase enzyme family EcKinase PF02958.15 KEP62172.1 - 0.0039 16.3 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KEP62172.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family PAT1 PF09770.4 KEP62173.1 - 5.7 5.0 15.3 7.5 4.6 10.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chorion_2 PF03964.10 KEP62175.1 - 0.037 14.5 0.5 0.037 14.5 0.4 9.5 5 2 1 8 8 8 0 Chorion family 2 DUF1049 PF06305.6 KEP62175.1 - 0.3 10.5 0.1 0.67 9.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Seryl_tRNA_N PF02403.17 KEP62176.1 - 1.1 9.2 8.2 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TBCC PF07986.7 KEP62177.1 - 9.1e-19 67.0 0.0 1.6e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Kelch_4 PF13418.1 KEP62178.1 - 8e-18 63.9 8.8 2.1e-05 24.1 0.0 6.8 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KEP62178.1 - 6.6e-16 57.3 3.3 0.00072 19.2 0.0 7.2 7 0 0 7 7 7 3 Kelch motif Kelch_3 PF13415.1 KEP62178.1 - 1.9e-15 56.5 33.2 4.8e-07 29.7 0.1 10.5 10 0 0 10 10 10 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KEP62178.1 - 9.3e-15 53.9 0.4 0.013 15.0 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 KEP62178.1 - 1.3e-13 50.5 8.0 0.00056 19.8 0.0 6.9 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.1 KEP62178.1 - 5.9e-11 42.0 5.5 0.0053 16.8 0.0 6.6 7 0 0 7 7 7 2 Kelch motif Hamartin PF04388.7 KEP62179.1 - 1.7 7.2 3.7 3.5 6.1 2.6 1.5 1 0 0 1 1 1 0 Hamartin protein MIP-T3 PF10243.4 KEP62180.1 - 3.7 5.9 33.5 6.2 5.1 23.2 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ebola_NP PF05505.7 KEP62180.1 - 6.1 4.7 11.8 9.1 4.1 8.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein ThiF PF00899.16 KEP62181.1 - 3e-33 114.5 0.1 5.9e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KEP62181.1 - 2.4e-22 78.2 0.0 4e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 KEP62181.1 - 9.5e-18 63.7 0.3 1.7e-17 62.9 0.2 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 KEP62181.1 - 5.9e-14 51.1 4.8 9.2e-14 50.5 2.7 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KEP62181.1 - 6.6e-05 23.0 0.0 0.0002 21.4 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IDO PF01231.13 KEP62181.1 - 0.15 10.4 0.0 0.3 9.4 0.0 1.4 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase BUD22 PF09073.5 KEP62181.1 - 5.3 5.9 10.8 7.9 5.4 7.5 1.2 1 0 0 1 1 1 0 BUD22 CytochromB561_N PF09786.4 KEP62181.1 - 6.1 5.1 12.5 8.4 4.7 8.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SNF PF00209.13 KEP62182.1 - 5.7e-94 315.4 33.3 9.6e-55 186.0 8.8 2.5 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family zf-rbx1 PF12678.2 KEP62183.1 - 2e-06 27.8 5.0 4.7e-06 26.6 3.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEP62183.1 - 3.2e-05 23.6 9.5 9.2e-05 22.1 6.6 1.9 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 KEP62183.1 - 0.00012 21.9 5.9 0.00039 20.3 4.1 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KEP62183.1 - 0.0029 17.3 3.2 0.0073 16.1 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KEP62183.1 - 0.013 15.0 10.0 0.03 13.9 6.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Arylsulfotran_2 PF14269.1 KEP62183.1 - 7.7 5.5 0.0 13 4.8 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) DEAD PF00270.24 KEP62184.1 - 1e-19 70.6 0.0 1.7e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62184.1 - 4.2e-16 58.5 0.0 9.3e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP62184.1 - 4.4e-05 23.3 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.18 KEP62184.1 - 0.011 15.4 2.0 0.012 15.2 0.0 2.2 2 0 0 2 2 2 0 HRDC domain MIF4G_like_2 PF09090.6 KEP62185.1 - 0.035 13.3 0.0 1.1 8.4 0.0 2.9 2 1 1 3 3 3 0 MIF4G like WD40 PF00400.27 KEP62186.1 - 7.4e-27 92.2 4.2 2.1e-07 30.5 0.0 6.0 5 1 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KEP62186.1 - 2.8e-15 55.9 0.4 5.8e-15 54.9 0.3 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3584 PF12128.3 KEP62187.1 - 4.3e-05 21.1 47.8 4.3e-05 21.1 33.1 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF3584) Spc7 PF08317.6 KEP62187.1 - 0.00057 18.6 20.3 0.00057 18.6 14.0 5.0 1 1 5 6 6 6 1 Spc7 kinetochore protein Filament PF00038.16 KEP62187.1 - 0.63 9.4 91.1 1.1 8.6 23.6 5.1 1 1 1 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 KEP62187.1 - 6.1 5.1 74.1 0.5 8.7 7.9 3.7 1 1 2 3 3 3 0 AAA domain DUF3689 PF12463.3 KEP62188.1 - 8.4e-36 123.2 0.5 1.7e-13 50.0 0.0 5.0 5 0 0 5 5 5 5 Protein of unknown function (DUF3689) UDPGP PF01704.13 KEP62189.1 - 1e-26 93.4 0.0 6.2e-22 77.6 0.0 3.1 3 0 0 3 3 3 3 UTP--glucose-1-phosphate uridylyltransferase Oxysterol_BP PF01237.13 KEP62191.1 - 4.6e-124 413.4 0.0 7.4e-124 412.8 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 KEP62191.1 - 1.1e-07 31.9 0.1 2e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 PH domain CENP-Q PF13094.1 KEP62191.1 - 0.0036 17.3 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit PH_11 PF15413.1 KEP62191.1 - 0.33 11.2 1.8 4.2 7.6 0.2 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain DUF2428 PF10350.4 KEP62192.1 - 2.8e-15 56.0 0.9 6.3e-11 41.7 0.1 3.4 3 0 0 3 3 3 2 Putative death-receptor fusion protein (DUF2428) PSD5 PF07637.6 KEP62195.1 - 0.022 14.7 0.0 0.12 12.4 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) BCNT PF07572.7 KEP62198.1 - 4.7e-16 58.4 0.7 4.7e-16 58.4 0.5 2.3 2 0 0 2 2 2 1 Bucentaur or craniofacial development RII_binding_1 PF10522.4 KEP62199.1 - 0.017 15.1 0.6 0.16 12.1 0.1 2.4 2 0 0 2 2 2 0 RII binding domain EF-hand_6 PF13405.1 KEP62199.1 - 0.018 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 KEP62199.1 - 0.044 13.9 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain pair Cyclin_N PF00134.18 KEP62200.1 - 3e-11 42.9 0.3 8.5e-11 41.5 0.0 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEP62200.1 - 3e-05 23.9 0.1 0.0027 17.6 0.0 3.0 2 1 1 3 3 3 1 Cyclin, C-terminal domain DNA_pol_B PF00136.16 KEP62202.1 - 7.6e-67 226.0 0.0 1.5e-66 225.0 0.0 1.4 2 0 0 2 2 2 1 DNA polymerase family B zf-C4pol PF14260.1 KEP62202.1 - 9.9e-11 41.4 2.7 9.9e-11 41.4 1.9 2.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 KEP62202.1 - 2.4e-05 23.3 0.0 0.0024 16.8 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain SAG PF04092.8 KEP62203.1 - 1.9e-84 280.2 120.6 9.2e-09 35.7 0.1 16.8 15 1 1 16 16 16 14 SRS domain PGM_PMM_I PF02878.11 KEP62204.1 - 2.2e-16 59.6 0.0 8.1e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 KEP62204.1 - 2.3e-07 30.7 0.0 7.2e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 KEP62204.1 - 1.8e-05 24.9 0.3 0.001 19.3 0.2 2.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Transglut_core2 PF13369.1 KEP62204.1 - 0.079 12.4 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Bromodomain PF00439.20 KEP62205.1 - 6.3e-13 48.4 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Cwf_Cwc_15 PF04889.7 KEP62205.1 - 7.6 6.1 13.2 4.1 7.0 6.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRM_1 PF00076.17 KEP62209.1 - 5.8e-36 121.9 0.1 1.1e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62209.1 - 1.6e-25 88.8 0.1 8.4e-12 44.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62209.1 - 1.1e-07 31.6 0.0 0.0056 16.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEP62209.1 - 0.00045 20.0 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KEP62209.1 - 0.01 15.5 0.0 0.087 12.6 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 KEP62209.1 - 0.025 14.0 0.4 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain ACDC PF14733.1 KEP62211.1 - 5.2e-20 71.3 0.0 1e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 KEP62211.1 - 7.7e-20 70.7 3.9 2.1e-10 40.5 0.1 2.4 2 0 0 2 2 2 2 AP2 domain AP2 PF00847.15 KEP62212.1 - 9.5e-06 25.6 0.6 1.6e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 AP2 domain Podoplanin PF05808.6 KEP62213.1 - 0.0013 18.3 2.6 0.0013 18.3 1.8 2.0 2 0 0 2 2 2 1 Podoplanin Sin_N PF04801.8 KEP62215.1 - 5.3e-49 167.2 10.4 1.8e-25 89.7 0.0 4.5 4 1 0 4 4 4 3 Sin-like protein conserved region DUF1957 PF09210.6 KEP62215.1 - 0.076 13.0 5.1 2.2 8.3 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1957) GOLD_2 PF13897.1 KEP62215.1 - 0.14 12.4 1.7 0.37 11.0 1.2 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.9 KEP62215.1 - 1.5 6.7 6.9 2.7 5.9 4.8 1.5 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KEP62215.1 - 9.8 5.3 7.0 19 4.3 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein Topoisom_bac PF01131.15 KEP62216.1 - 2.4e-92 309.8 0.0 3.1e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KEP62216.1 - 8.4e-15 54.5 0.0 2e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF86 PF01934.12 KEP62216.1 - 0.099 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF86 HypA PF01155.14 KEP62216.1 - 0.2 11.3 11.1 0.16 11.6 0.1 3.1 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family SRPRB PF09439.5 KEP62217.1 - 2.1e-22 79.2 0.2 5.6e-21 74.5 0.2 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KEP62217.1 - 3.2e-13 49.2 0.0 2.6e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEP62217.1 - 6.4e-09 35.4 0.0 5.5e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEP62217.1 - 1.8e-08 34.8 0.1 3.8e-08 33.8 0.1 1.5 1 1 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KEP62217.1 - 2.3e-08 33.4 0.0 3.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEP62217.1 - 3.4e-08 33.1 0.0 4.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEP62217.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KEP62217.1 - 0.00033 20.1 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 KEP62217.1 - 0.0012 18.8 5.6 0.0031 17.5 3.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 KEP62217.1 - 0.0021 18.3 0.1 0.004 17.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 KEP62217.1 - 0.0055 16.3 1.1 0.033 13.8 0.7 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEP62217.1 - 0.0067 16.5 0.1 0.018 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 KEP62217.1 - 0.0072 16.1 1.7 0.021 14.6 0.0 2.2 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 KEP62217.1 - 0.012 14.9 0.1 0.53 9.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B cobW PF02492.14 KEP62217.1 - 0.021 14.2 0.3 3.4 7.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 KEP62217.1 - 0.029 13.9 0.6 0.23 10.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KEP62217.1 - 0.03 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEP62217.1 - 0.38 10.3 1.6 0.78 9.3 1.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Interferon PF00143.14 KEP62218.1 - 0.025 14.4 1.2 0.045 13.6 0.8 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain Laminin_II PF06009.7 KEP62218.1 - 0.037 13.7 1.8 0.091 12.5 1.2 1.6 1 0 0 1 1 1 0 Laminin Domain II V_ATPase_I PF01496.14 KEP62218.1 - 0.32 8.8 0.2 0.46 8.2 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lipoprotein_20 PF13942.1 KEP62218.1 - 0.35 10.3 2.7 0.61 9.6 1.9 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Ras PF00071.17 KEP62219.1 - 6.9e-14 51.5 0.1 9.1e-11 41.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEP62219.1 - 5e-07 30.2 0.0 0.012 16.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KEP62219.1 - 0.035 13.3 0.0 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEP62219.1 - 0.043 13.6 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.1 KEP62219.1 - 0.05 13.5 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEP62219.1 - 0.086 12.5 0.1 0.35 10.5 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase GTP_EFTU PF00009.22 KEP62219.1 - 0.1 12.0 0.0 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Trypsin_2 PF13365.1 KEP62220.1 - 5e-13 49.1 1.4 8.7e-13 48.3 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 KEP62220.1 - 7.3e-13 48.6 0.3 1.2e-12 47.8 0.2 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 KEP62220.1 - 4.3e-08 32.9 0.0 1e-06 28.4 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 KEP62220.1 - 1.3e-05 25.2 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S7 PF00949.16 KEP62220.1 - 0.0064 15.8 0.1 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease UPF0020 PF01170.13 KEP62221.1 - 3.6e-15 55.9 0.0 1.9e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KEP62221.1 - 3.1e-11 43.3 0.0 6.5e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 KEP62221.1 - 2.3e-06 27.3 0.0 0.001 18.5 0.0 2.4 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 KEP62221.1 - 0.21 10.6 0.0 3.2 6.7 0.0 2.0 2 0 0 2 2 2 0 N-6 DNA Methylase UCH PF00443.24 KEP62224.1 - 7.3e-33 113.8 0.0 1.4e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP62224.1 - 1.6e-12 47.4 0.0 9e-12 45.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cytadhesin_P30 PF07271.6 KEP62224.1 - 0.64 9.2 26.6 0.012 14.9 13.2 1.9 2 0 0 2 2 2 0 Cytadhesin P30/P32 TSP_1 PF00090.14 KEP62225.1 - 5e-06 26.5 2.7 5e-06 26.5 1.8 4.1 4 1 0 4 4 4 1 Thrombospondin type 1 domain DUF2217 PF10265.4 KEP62225.1 - 2.7 6.6 17.6 6.4 5.4 12.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF605 PF04652.11 KEP62225.1 - 7.8 5.7 20.4 0.042 13.2 4.4 2.7 3 0 0 3 3 3 0 Vta1 like CLIP PF12032.3 KEP62226.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases PQQ_3 PF13570.1 KEP62227.1 - 0.032 14.5 2.0 25 5.2 0.0 4.8 6 0 0 6 6 6 0 PQQ-like domain DUF4316 PF14195.1 KEP62227.1 - 0.77 9.8 6.0 0.28 11.2 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Lipase_3 PF01764.20 KEP62229.1 - 1.9e-16 59.9 0.0 3.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Apt1 PF10351.4 KEP62229.1 - 5 5.8 13.6 2.5 6.8 4.3 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Glycos_transf_2 PF00535.21 KEP62230.1 - 6.6e-31 107.2 0.0 8e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEP62230.1 - 1.1e-11 44.9 0.0 3.4e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KEP62230.1 - 2.4e-06 26.8 0.0 3.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEP62230.1 - 0.00024 20.4 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Dynein_light PF01221.13 KEP62231.1 - 5.5e-25 87.1 0.2 6.6e-25 86.9 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 KEP62231.1 - 0.022 15.0 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Ground-like domain OTU PF02338.14 KEP62232.1 - 1.8e-08 34.9 0.0 3.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.2 KEP62232.1 - 0.042 13.9 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PAS_3 PF08447.6 KEP62234.1 - 0.0097 15.9 0.1 1.5 8.9 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 KEP62234.1 - 0.055 13.8 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 PAS domain EpsG PF14897.1 KEP62234.1 - 1.2 7.9 3.6 2 7.2 2.5 1.2 1 0 0 1 1 1 0 EpsG family G-patch PF01585.18 KEP62235.1 - 7.9e-12 44.7 0.1 7.9e-12 44.7 0.1 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KEP62235.1 - 1.4e-10 40.8 0.1 1.4e-10 40.8 0.1 3.7 2 1 0 2 2 2 1 DExH-box splicing factor binding site LEAP-2 PF07359.6 KEP62236.1 - 0.12 12.0 1.1 0.16 11.6 0.4 1.5 1 1 1 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Proteasome PF00227.21 KEP62237.1 - 4e-53 179.5 0.0 4.9e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEP62237.1 - 6.9e-14 50.8 0.5 1.5e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Mre11_DNA_bind PF04152.9 KEP62238.1 - 4.8e-30 104.7 0.1 1.2e-25 90.4 0.0 3.0 2 1 0 2 2 2 2 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KEP62238.1 - 1.2e-22 80.2 0.4 2.1e-22 79.5 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEP62238.1 - 0.00051 19.8 0.2 0.0031 17.3 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF605 PF04652.11 KEP62239.1 - 4.6 6.5 17.8 5.9 6.1 12.3 1.2 1 0 0 1 1 1 0 Vta1 like Glucan_synthase PF02364.10 KEP62241.1 - 4.5e-135 451.5 22.6 3.7e-113 379.0 10.2 3.0 3 1 0 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KEP62241.1 - 3.5e-20 72.0 0.2 1.1e-19 70.4 0.1 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 CAP PF00188.21 KEP62242.1 - 1.1e-14 54.9 6.9 2.2e-14 54.0 4.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Hydrolase_like2 PF13246.1 KEP62243.1 - 0.057 13.3 0.1 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit V-SNARE PF05008.10 KEP62245.1 - 2.3e-11 43.6 0.2 6.2e-11 42.3 0.1 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KEP62245.1 - 4.1e-07 29.9 1.2 1.2e-06 28.4 0.8 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEP62245.1 - 0.0066 16.1 0.3 0.02 14.5 0.2 1.8 2 0 0 2 2 2 1 Sec20 IQ PF00612.22 KEP62245.1 - 0.15 11.7 0.7 0.3 10.8 0.5 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF678 PF05077.7 KEP62246.1 - 0.061 13.3 1.5 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DUF1510 PF07423.6 KEP62247.1 - 3.7 6.8 10.4 13 5.0 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 KEP62250.1 - 0.00054 18.5 17.9 0.00054 18.5 12.4 6.9 8 0 0 8 8 8 2 Microtubule-binding protein MIP-T3 HCBP_related PF06594.6 KEP62250.1 - 0.13 11.8 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain MRP-L46 PF11788.3 KEP62251.1 - 0.11 13.1 1.8 0.3 11.7 1.2 1.8 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Prenyltrans PF00432.16 KEP62252.1 - 1.4e-28 98.0 12.0 2.5e-11 42.9 0.2 7.3 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEP62252.1 - 1.1e-18 67.6 0.1 1.8e-13 50.8 0.1 3.4 3 1 0 3 3 3 2 Prenyltransferase-like zf-RanBP PF00641.13 KEP62253.1 - 6e-06 25.2 4.5 6e-06 25.2 3.1 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 KEP62253.1 - 8.9 5.9 12.5 0.4 10.2 0.1 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger FAST_1 PF06743.10 KEP62255.1 - 0.0011 18.5 0.7 2.6 7.8 0.0 3.4 2 1 2 4 4 4 2 FAST kinase-like protein, subdomain 1 PAP_assoc PF03828.14 KEP62256.1 - 1e-06 28.6 0.4 0.00079 19.3 0.1 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEP62256.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain OAS1_C PF10421.4 KEP62256.1 - 0.28 10.6 0.1 0.53 9.7 0.0 1.3 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Nop10p PF04135.7 KEP62257.1 - 5.5e-21 74.0 0.6 7.2e-21 73.6 0.4 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CAF1C_H4-bd PF12265.3 KEP62259.1 - 5.8e-14 51.7 0.1 4e-13 49.0 0.1 2.4 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 KEP62259.1 - 2.9e-11 42.8 11.8 1.7e-06 27.6 0.1 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat DUF605 PF04652.11 KEP62260.1 - 4.5 6.5 21.1 6.5 6.0 14.6 1.3 1 0 0 1 1 1 0 Vta1 like DUF605 PF04652.11 KEP62262.1 - 1.9 7.7 20.6 2.9 7.2 14.3 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KEP62262.1 - 8.6 4.4 8.4 11 4.0 5.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4425 PF14466.1 KEP62264.1 - 0.00068 19.7 2.1 0.67 10.0 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4425) Phage_tail PF04630.7 KEP62264.1 - 0.0017 17.4 0.1 17 4.4 0.0 3.3 3 0 0 3 3 3 3 Phage major tail protein VIT PF08487.5 KEP62264.1 - 0.022 14.4 0.0 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain Lipoprot_C PF08794.5 KEP62264.1 - 0.26 11.1 2.8 76 3.1 0.0 3.3 3 0 0 3 3 3 0 Lipoprotein GNA1870 C terminal like DUF605 PF04652.11 KEP62266.1 - 0.062 12.6 14.8 0.073 12.4 10.2 1.1 1 0 0 1 1 1 0 Vta1 like Ribosomal_60s PF00428.14 KEP62266.1 - 1.4 9.4 9.7 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein S1_2 PF13509.1 KEP62272.1 - 0.01 15.7 0.0 6.6 6.7 0.0 2.3 2 0 0 2 2 2 2 S1 domain DUF605 PF04652.11 KEP62275.1 - 0.045 13.1 15.4 0.057 12.8 10.7 1.3 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 KEP62275.1 - 3.3 5.5 11.0 4.3 5.1 7.6 1.0 1 0 0 1 1 1 0 Nop14-like family SNF2_N PF00176.18 KEP62276.1 - 7.7e-64 215.3 0.0 1.3e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP62276.1 - 1.7e-14 53.4 0.0 3.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 KEP62276.1 - 2.7e-11 43.2 0.0 7.1e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 Bromodomain HDA2-3 PF11496.3 KEP62276.1 - 3.6e-11 42.4 0.0 8.1e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KEP62276.1 - 4.8e-09 36.3 0.0 1.8e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEP62276.1 - 0.16 11.4 0.0 6.4 6.2 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Transmemb_17 PF09799.4 KEP62278.1 - 2e-08 34.5 4.2 2e-08 34.5 2.9 1.9 1 1 1 2 2 2 1 Predicted membrane protein Med19 PF10278.4 KEP62280.1 - 0.25 10.9 9.5 0.28 10.8 6.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 BLVR PF06375.6 KEP62280.1 - 0.99 9.2 6.7 0.91 9.3 4.7 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) U79_P34 PF03064.11 KEP62280.1 - 2.1 7.8 8.7 2.1 7.7 6.0 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CMS1 PF14617.1 KEP62280.1 - 3.6 6.5 5.2 3.5 6.6 3.6 1.0 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zf-C3HC4_2 PF13923.1 KEP62281.1 - 0.011 15.7 1.0 0.26 11.3 1.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RBB1NT PF08169.6 KEP62281.1 - 0.051 13.5 0.2 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 RBB1NT (NUC162) domain OmpH PF03938.9 KEP62281.1 - 0.15 11.9 4.6 0.29 11.0 3.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4355 PF14265.1 KEP62281.1 - 2.9 7.8 15.8 5.6 6.9 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) FtsJ PF01728.14 KEP62282.1 - 1.8e-19 70.4 0.0 1.1e-18 67.8 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.1 KEP62282.1 - 0.085 10.6 0.0 0.14 10.0 0.0 1.2 1 0 0 1 1 1 0 Virus-capping methyltransferase Ribosomal_60s PF00428.14 KEP62282.1 - 2.9 8.3 21.1 0.13 12.6 4.8 3.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein DDHD PF02862.12 KEP62282.1 - 8.6 6.0 7.1 1.9 8.1 0.3 2.8 2 1 0 2 2 2 0 DDHD domain PP2C PF00481.16 KEP62283.1 - 1.1e-38 133.0 0.0 3.6e-31 108.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KEP62283.1 - 0.0021 17.7 0.0 0.19 11.3 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Glycos_transf_2 PF00535.21 KEP62284.1 - 1.1e-22 80.4 0.0 1.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KEP62284.1 - 9e-14 51.5 0.1 6.4e-12 45.6 0.2 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 KEP62284.1 - 1.1e-12 48.2 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 KEP62284.1 - 2.4e-11 42.9 0.1 6.3e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KEP62284.1 - 2.7e-05 23.3 0.0 4.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 FAM183 PF14886.1 KEP62285.1 - 2.6e-05 24.7 0.2 2.8e-05 24.6 0.2 1.4 1 1 0 1 1 1 1 FAM183A and FAM183B related LLC1 PF14945.1 KEP62285.1 - 0.027 14.7 0.1 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein MBF1 PF08523.5 KEP62286.1 - 3.9e-20 71.6 1.3 3.9e-20 71.6 0.9 1.9 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KEP62286.1 - 3.5e-15 55.5 0.1 5.9e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KEP62286.1 - 9.5e-11 41.7 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KEP62286.1 - 7.8e-09 35.4 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 KEP62286.1 - 0.014 15.1 0.4 0.028 14.1 0.2 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.1 KEP62286.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NUDE_C PF04880.8 KEP62286.1 - 0.043 14.1 1.0 0.05 13.9 0.7 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region GTP_EFTU PF00009.22 KEP62288.1 - 3.1e-36 124.5 0.1 1.3e-35 122.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEP62288.1 - 5.9e-18 64.7 0.0 8.6e-14 51.3 0.0 2.5 2 0 0 2 2 2 2 Translation-initiation factor 2 MMR_HSR1 PF01926.18 KEP62288.1 - 9.6e-07 28.7 0.0 2.3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP62288.1 - 8e-05 21.9 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KEP62288.1 - 0.00017 22.0 0.2 0.0005 20.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEP62288.1 - 0.0018 17.5 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEP62288.1 - 0.0018 17.5 0.1 0.0051 16.0 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KEP62288.1 - 0.0021 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU_D4 PF14578.1 KEP62288.1 - 0.015 14.9 0.9 0.49 10.0 0.1 2.7 2 0 0 2 2 2 0 Elongation factor Tu domain 4 MobB PF03205.9 KEP62288.1 - 0.04 13.6 0.0 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KEP62288.1 - 0.057 13.2 0.0 5.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.4 KEP62288.1 - 0.095 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KEP62288.1 - 0.63 9.5 0.0 1.6 8.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CENP-F_leu_zip PF10473.4 KEP62289.1 - 0.0037 17.1 6.6 0.0037 17.1 4.6 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.4 KEP62289.1 - 0.0041 15.4 10.7 0.0057 15.0 7.4 1.1 1 0 0 1 1 1 1 Transmembrane protein NAGidase PF07555.8 KEP62289.1 - 0.1 11.4 0.0 0.24 10.3 0.0 1.6 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Lge1 PF11488.3 KEP62289.1 - 0.16 12.1 6.5 0.25 11.5 2.5 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 KEP62289.1 - 0.16 11.5 9.9 0.33 10.5 6.8 1.5 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KEP62289.1 - 0.2 11.4 13.8 0.039 13.7 5.9 2.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 KEP62289.1 - 0.73 9.7 3.1 0.65 9.9 0.1 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 KEP62289.1 - 1.3 9.3 6.4 0.57 10.5 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 KEP62289.1 - 2.4 7.7 5.9 5.3 6.6 3.4 2.1 1 1 0 1 1 1 0 Septum formation initiator zf-DHHC PF01529.15 KEP62290.1 - 0.0083 15.5 4.2 0.024 14.0 2.9 1.9 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF605 PF04652.11 KEP62293.1 - 0.15 11.4 17.4 0.17 11.2 12.0 1.1 1 0 0 1 1 1 0 Vta1 like TPR_11 PF13414.1 KEP62294.1 - 1.1e-30 105.0 8.9 1.9e-12 46.6 0.4 5.4 3 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 KEP62294.1 - 1.4e-23 81.4 4.5 2.7e-06 26.7 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP62294.1 - 1.7e-22 77.4 3.3 1.9e-05 24.1 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62294.1 - 8.1e-21 72.6 0.6 0.0007 20.0 0.0 8.2 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEP62294.1 - 1.3e-20 73.4 0.6 1.7e-05 25.0 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62294.1 - 2.8e-18 66.0 4.5 1.3e-07 32.1 0.0 5.3 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEP62294.1 - 4.9e-18 63.7 7.4 0.00048 20.1 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62294.1 - 1.2e-16 59.1 0.2 2.3e-05 23.8 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP62294.1 - 2.6e-15 56.0 2.9 7.5e-06 25.7 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP62294.1 - 3.6e-15 55.6 2.6 3.5e-07 30.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEP62294.1 - 3.1e-14 52.3 0.0 0.16 12.5 0.0 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEP62294.1 - 8.6e-10 37.6 0.3 0.016 14.9 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEP62294.1 - 3.1e-09 36.8 6.8 0.00013 22.0 0.1 4.3 3 1 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KEP62294.1 - 3.2e-09 36.8 6.8 0.00092 19.3 0.2 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEP62294.1 - 1.3e-05 24.9 1.7 0.015 15.2 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat BTAD PF03704.12 KEP62294.1 - 0.00073 19.8 5.5 0.012 15.9 0.0 3.7 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 KEP62294.1 - 0.0014 17.7 0.4 0.086 11.8 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 KEP62294.1 - 0.012 14.3 0.1 0.021 13.5 0.1 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.4 KEP62294.1 - 0.044 13.0 0.0 0.25 10.5 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR NARP1 PF12569.3 KEP62294.1 - 0.052 12.3 0.0 0.052 12.3 0.0 3.5 3 1 0 3 3 2 0 NMDA receptor-regulated protein 1 zf-MIZ PF02891.15 KEP62295.1 - 4.3e-16 58.1 3.4 8.9e-16 57.1 2.4 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 KEP62295.1 - 0.00023 20.5 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain DUF2296 PF10058.4 KEP62295.1 - 0.0074 16.0 7.4 0.084 12.6 1.2 2.6 2 0 0 2 2 2 2 Predicted integral membrane metal-binding protein (DUF2296) PINIT PF14324.1 KEP62295.1 - 0.0077 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.3 KEP62295.1 - 0.1 12.1 1.5 0.19 11.2 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 KEP62295.1 - 0.23 11.1 16.4 0.35 10.6 4.8 2.7 2 0 0 2 2 2 0 PHD-finger E1-E2_ATPase PF00122.15 KEP62296.1 - 4.5e-61 205.8 3.1 7.8e-61 205.0 2.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEP62296.1 - 4.3e-33 114.3 0.0 4.3e-33 114.3 0.0 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEP62296.1 - 4.9e-32 112.0 2.2 5.2e-27 95.6 0.1 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEP62296.1 - 1.2e-21 75.9 0.0 2.7e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEP62296.1 - 2e-16 59.6 0.1 8.5e-16 57.6 0.0 2.1 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEP62296.1 - 1.3e-15 58.1 0.0 4.5e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEP62296.1 - 1.3e-05 24.9 0.8 0.0014 18.2 0.5 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UQ_con PF00179.21 KEP62297.1 - 1.1e-16 60.5 0.0 1.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_A PF14457.1 KEP62297.1 - 0.044 13.2 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family A RWD PF05773.17 KEP62297.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain CPW_WPC PF09717.5 KEP62299.1 - 4.9e-33 113.5 12.5 1.5e-16 60.7 4.2 2.3 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) PapD-like PF14874.1 KEP62301.1 - 3.2e-06 27.0 0.1 9.3e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 Flagellar-associated PapD-like Motile_Sperm PF00635.21 KEP62301.1 - 0.00019 21.0 0.0 0.066 12.8 0.0 2.4 2 0 0 2 2 2 2 MSP (Major sperm protein) domain WD40 PF00400.27 KEP62303.1 - 0.00049 19.8 4.6 9.9 6.2 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Orn_Arg_deC_N PF02784.11 KEP62304.1 - 2.2e-39 135.1 0.0 3e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KEP62304.1 - 1.6e-13 50.3 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AT_hook PF02178.14 KEP62305.1 - 2.8e-06 26.3 28.4 0.014 15.0 1.2 4.1 3 0 0 3 3 3 3 AT hook motif ubiquitin PF00240.18 KEP62309.1 - 2.9e-06 26.5 0.0 6.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEP62309.1 - 0.0028 17.3 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Tctex-1 PF03645.8 KEP62310.1 - 1.5e-25 88.9 0.0 1.8e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family MFS_1 PF07690.11 KEP62312.1 - 9.9e-24 83.6 41.3 1.1e-21 76.9 9.1 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Collagen PF01391.13 KEP62312.1 - 8.9 5.9 48.2 0.44 10.1 9.2 4.3 3 1 1 4 4 4 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 KEP62313.1 - 0.07 11.8 0.0 0.07 11.8 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.6 KEP62314.1 - 1 8.9 0.1 1.8 8.2 0.1 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling G6PD_C PF02781.11 KEP62315.1 - 4.2e-108 360.6 0.0 6e-108 360.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KEP62315.1 - 6.1e-55 186.2 0.0 1.5e-54 185.0 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.15 KEP62315.1 - 1.1e-33 116.6 0.0 3.8e-33 114.8 0.0 1.8 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase zf-DHHC PF01529.15 KEP62317.1 - 2.8e-37 127.7 11.9 2.8e-37 127.7 8.2 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Myosin_head PF00063.16 KEP62319.1 - 1.9e-193 644.2 0.0 7.3e-193 642.3 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) WD40 PF00400.27 KEP62319.1 - 1.8e-12 46.5 7.3 0.0013 18.5 0.3 6.8 7 0 0 7 7 6 3 WD domain, G-beta repeat AAA_22 PF13401.1 KEP62319.1 - 0.00023 21.2 0.2 0.85 9.7 0.0 3.6 4 0 0 4 4 3 2 AAA domain IQ PF00612.22 KEP62319.1 - 0.00055 19.3 23.2 0.02 14.4 0.0 5.2 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_5 PF07728.9 KEP62319.1 - 0.00066 19.4 0.2 0.028 14.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Miro PF08477.8 KEP62319.1 - 0.0026 18.2 0.0 0.017 15.6 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KEP62319.1 - 0.0068 16.4 13.9 0.11 12.4 0.0 4.3 3 1 0 3 3 2 2 AAA ATPase domain RNA_helicase PF00910.17 KEP62319.1 - 0.013 15.7 0.0 12 6.0 0.0 3.5 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.7 KEP62319.1 - 0.016 14.8 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 KEP62319.1 - 0.04 14.2 3.2 5 7.4 0.0 3.9 4 1 0 4 4 3 0 ABC transporter AAA_29 PF13555.1 KEP62319.1 - 0.077 12.5 0.1 6.4 6.3 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KEP62319.1 - 0.1 13.3 2.8 15 6.4 0.0 4.3 4 0 0 4 4 4 0 AAA domain Sen15 PF09631.5 KEP62319.1 - 0.12 12.5 0.2 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Sen15 protein KaiC PF06745.8 KEP62319.1 - 0.18 10.8 0.0 9.2 5.3 0.0 2.7 2 0 0 2 2 2 0 KaiC TBPIP PF07106.8 KEP62319.1 - 3.3 7.2 16.0 2.7 7.5 5.0 3.3 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CorA PF01544.13 KEP62319.1 - 4.4 6.2 5.6 9.3 5.1 3.9 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GDA1_CD39 PF01150.12 KEP62320.1 - 1.1e-64 218.5 0.0 3e-43 147.9 0.0 2.8 2 2 1 3 3 3 2 GDA1/CD39 (nucleoside phosphatase) family Phosphorylase PF00343.15 KEP62320.1 - 0.096 10.5 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase DUF4116 PF13475.1 KEP62320.1 - 0.14 11.6 0.1 28 4.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) GDA1_CD39 PF01150.12 KEP62321.1 - 8.1e-72 242.0 0.0 5.2e-70 236.1 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF3530 PF12048.3 KEP62321.1 - 0.077 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF4177 PF13783.1 KEP62321.1 - 0.13 11.9 0.2 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) CASP_C PF08172.7 KEP62323.1 - 8.9e-09 34.7 0.6 8.9e-09 34.7 0.4 5.4 4 1 3 7 7 7 2 CASP C terminal Kdo PF06293.9 KEP62324.1 - 1.1e-12 47.4 0.0 1.3e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KEP62324.1 - 9.4e-08 31.5 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEP62324.1 - 1.5e-06 28.1 3.4 4.4e-05 23.3 0.5 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KEP62324.1 - 0.00041 19.5 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KEP62324.1 - 0.00068 19.0 0.0 0.013 14.8 0.0 2.4 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.15 KEP62324.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PALP PF00291.20 KEP62325.1 - 4.4e-55 187.0 0.0 6.1e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ORC6 PF05460.8 KEP62325.1 - 0.038 13.0 2.1 0.053 12.6 1.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1442 PF07279.6 KEP62325.1 - 0.045 12.8 0.1 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) Tetraspannin PF00335.15 KEP62326.1 - 0.092 12.0 7.5 0.22 10.7 0.4 2.5 1 1 1 2 2 2 0 Tetraspanin family Oxidored_q2 PF00420.19 KEP62326.1 - 1.1 8.8 4.8 8.1 6.1 0.7 2.3 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TTL PF03133.10 KEP62327.1 - 4e-83 278.7 0.1 5.7e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEP62327.1 - 5e-08 32.0 0.0 0.0016 17.2 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.1 KEP62327.1 - 0.15 11.1 0.0 6.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp HECT PF00632.20 KEP62328.1 - 3.7e-79 266.1 0.0 4.5e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LSM PF01423.17 KEP62329.1 - 4.6e-14 51.7 0.0 7.8e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEP62329.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Ataxin 2 SM domain zf-UBP PF02148.14 KEP62330.1 - 0.2 11.8 0.4 0.36 10.9 0.3 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C14 PF00656.17 KEP62332.1 - 3.4e-31 108.8 0.0 5.6e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Mito_carr PF00153.22 KEP62333.1 - 1.4e-34 117.6 11.7 5.6e-19 67.6 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.10 KEP62333.1 - 0.039 12.9 0.2 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Arsenical pump membrane protein Spc97_Spc98 PF04130.8 KEP62334.1 - 1.9e-55 188.2 0.0 2.1e-35 122.0 0.0 3.0 2 1 0 2 2 2 2 Spc97 / Spc98 family Glycos_transf_1 PF00534.15 KEP62335.1 - 2.7e-39 134.3 0.0 4.6e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KEP62335.1 - 2.3e-23 83.0 6.1 6.3e-23 81.6 0.4 3.5 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KEP62335.1 - 1.2e-18 67.4 1.6 1.2e-18 67.4 1.1 2.6 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KEP62335.1 - 2.1e-13 50.6 0.0 5.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KEP62335.1 - 2.4e-13 50.1 2.2 1.9e-10 40.6 1.2 3.2 2 1 0 2 2 2 1 Starch synthase catalytic domain CBM_48 PF02922.13 KEP62335.1 - 2.6e-12 46.6 0.2 1.7e-06 27.9 0.0 3.1 2 1 1 3 3 3 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.13 KEP62335.1 - 1.1e-10 41.5 0.0 3.8e-10 39.7 0.0 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KEP62335.1 - 7.4e-07 28.8 0.0 1e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_trans_1_2 PF13524.1 KEP62335.1 - 0.00064 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycogen_syn PF05693.8 KEP62335.1 - 0.059 11.6 0.1 0.39 8.9 0.0 2.1 2 0 0 2 2 2 0 Glycogen synthase Thioredoxin PF00085.15 KEP62337.1 - 4.3e-24 84.2 0.3 4.9e-13 48.6 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 KEP62337.1 - 1.6e-11 44.3 2.4 3.4e-08 33.5 0.1 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEP62337.1 - 1.3e-05 25.1 1.7 0.15 12.1 0.1 4.0 3 1 0 3 3 3 2 Thioredoxin-like HyaE PF07449.6 KEP62337.1 - 2.2e-05 24.3 0.1 0.01 15.7 0.0 3.6 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 KEP62337.1 - 0.0008 19.3 1.0 0.15 12.1 0.0 3.0 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEP62337.1 - 0.001 19.2 1.3 1.3 9.2 0.0 2.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KEP62337.1 - 0.039 13.7 0.2 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain 7TM_GPCR_Srab PF10292.4 KEP62338.1 - 0.049 12.3 0.0 0.053 12.2 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor EamA PF00892.15 KEP62339.1 - 7.8e-07 29.1 16.2 0.00037 20.5 0.1 3.8 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.10 KEP62339.1 - 1.1e-05 24.6 3.3 1.1e-05 24.6 2.3 1.9 2 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 KEP62339.1 - 1.2e-05 25.0 17.2 5.2e-05 22.9 6.3 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KEP62339.1 - 0.00024 20.1 8.7 0.00044 19.2 6.0 1.6 1 1 0 1 1 1 1 UAA transporter family DUF1129 PF06570.6 KEP62339.1 - 0.015 14.6 2.0 0.029 13.6 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PapJ PF14855.1 KEP62339.1 - 0.016 14.7 1.2 7.1 6.0 0.1 3.2 2 1 1 3 3 3 0 Pilus-assembly fibrillin subunit, chaperone EmrE PF13536.1 KEP62339.1 - 0.031 14.4 0.5 0.031 14.4 0.4 2.9 3 1 0 3 3 3 0 Multidrug resistance efflux transporter PAN_1 PF00024.21 KEP62341.1 - 1.7e-51 171.8 62.0 3.8e-08 32.9 2.1 8.3 6 2 0 8 8 8 8 PAN domain PAN_4 PF14295.1 KEP62341.1 - 9.5e-46 153.3 66.2 3.1e-06 26.7 1.7 8.7 8 0 0 8 8 8 8 PAN domain NOT2_3_5 PF04153.13 KEP62341.1 - 0.0034 17.2 7.8 9.5 6.1 0.1 5.4 5 0 0 5 5 5 1 NOT2 / NOT3 / NOT5 family DUF1923 PF09083.5 KEP62341.1 - 0.17 11.4 0.0 30 4.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Polyoma_lg_T_C PF06431.6 KEP62341.1 - 0.4 9.2 3.2 9.4 4.7 0.2 2.3 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus Mastoparan PF08249.6 KEP62341.1 - 1.1 9.9 2.3 53 4.7 0.1 2.5 2 0 0 2 2 2 0 Mastoparan protein Histone PF00125.19 KEP62342.1 - 1.5e-20 73.0 0.4 2.2e-20 72.5 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEP62342.1 - 0.00013 22.0 0.6 0.00018 21.4 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KEP62342.1 - 0.00068 19.8 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Asr PF06392.6 KEP62342.1 - 0.27 11.6 5.8 0.54 10.6 4.0 1.5 1 0 0 1 1 1 0 Acid shock protein repeat zf-His_Me_endon PF05551.6 KEP62344.1 - 0.039 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease RCC1 PF00415.13 KEP62346.1 - 3.6e-29 100.7 8.1 1.1e-07 31.8 0.0 8.8 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP62346.1 - 1.4e-13 50.0 37.5 1.5e-06 27.6 3.4 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Hydrolase_6 PF13344.1 KEP62347.1 - 6.9e-37 125.4 0.0 1.4e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEP62347.1 - 1.9e-11 43.4 0.1 1.5e-10 40.6 0.0 2.5 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 KEP62347.1 - 3.5e-05 24.3 0.0 0.00098 19.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KEP62347.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase MLANA PF14991.1 KEP62347.1 - 0.13 12.3 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein melan-A SRP40_C PF05022.7 KEP62348.1 - 1.7e-25 89.2 3.2 1.7e-25 89.2 2.2 2.3 2 1 0 2 2 2 1 SRP40, C-terminal domain Opi1 PF08618.5 KEP62348.1 - 0.31 9.9 7.2 0.41 9.5 5.0 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 DUF4554 PF15091.1 KEP62348.1 - 2.5 6.7 11.5 3.4 6.2 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) RRM_1 PF00076.17 KEP62349.1 - 6.9e-24 83.2 0.0 2.6e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62349.1 - 4.8e-15 55.2 0.0 8e-11 41.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62349.1 - 1.6e-08 34.2 0.0 6.9e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_6 PF13516.1 KEP62351.1 - 0.0031 17.4 0.0 3.6 7.9 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeat SNARE PF05739.14 KEP62352.1 - 3.7e-16 58.5 3.0 3.7e-16 58.5 2.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KEP62352.1 - 5e-05 23.4 1.8 5e-05 23.4 1.2 2.5 2 0 0 2 2 2 1 Syntaxin PBP1_TM PF14812.1 KEP62352.1 - 0.0014 18.9 0.6 0.32 11.3 0.0 2.5 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal MCPsignal PF00015.16 KEP62352.1 - 0.0016 18.0 1.2 0.0016 18.0 0.8 2.7 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain VitD-bind_III PF09164.5 KEP62352.1 - 0.021 14.4 0.0 0.087 12.4 0.0 2.1 1 0 0 1 1 1 0 Vitamin D binding protein, domain III CTK3 PF12243.3 KEP62352.1 - 0.028 14.0 0.4 0.059 12.9 0.0 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Reo_sigmaC PF04582.7 KEP62352.1 - 0.045 12.9 1.5 0.047 12.8 0.4 1.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein WXG100 PF06013.7 KEP62352.1 - 0.061 13.3 5.5 3.9 7.5 0.6 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 KEP62352.1 - 0.25 11.1 6.6 0.21 11.3 0.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Use1 PF09753.4 KEP62352.1 - 0.3 10.4 13.6 51 3.1 9.4 3.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 NPV_P10 PF05531.7 KEP62352.1 - 0.38 11.0 3.5 7.2 6.9 0.4 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Mit_KHE1 PF10173.4 KEP62352.1 - 0.78 9.5 7.1 0.26 11.1 0.2 2.6 1 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF912 PF06024.7 KEP62352.1 - 3.1 7.8 5.4 0.35 10.9 0.4 1.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Synaptobrevin PF00957.16 KEP62352.1 - 6.3 6.4 7.6 3.4 7.3 2.8 2.5 2 1 0 2 2 2 0 Synaptobrevin Form_Nir_trans PF01226.12 KEP62354.1 - 2.4e-73 246.1 15.2 2.8e-73 245.8 10.5 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Spore_permease PF03845.8 KEP62354.1 - 0.071 11.7 5.6 0.14 10.8 3.9 1.4 1 0 0 1 1 1 0 Spore germination protein Radical_SAM PF04055.16 KEP62355.1 - 9e-10 38.9 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KEP62355.1 - 0.00078 19.4 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KEP62355.1 - 0.0047 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain U79_P34 PF03064.11 KEP62355.1 - 0.018 14.5 13.0 0.038 13.5 9.0 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 VID27 PF08553.5 KEP62355.1 - 0.054 11.7 10.6 0.081 11.1 7.3 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nha1_C PF08619.5 KEP62355.1 - 0.081 12.1 27.0 0.029 13.6 0.7 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Daxx PF03344.10 KEP62355.1 - 0.14 10.6 26.0 0.31 9.4 18.0 1.5 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KEP62355.1 - 0.15 10.1 18.7 0.43 8.5 13.0 1.7 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 KEP62355.1 - 0.3 10.5 15.7 0.54 9.6 10.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 KEP62355.1 - 0.55 7.8 8.6 0.73 7.4 6.0 1.1 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 KEP62355.1 - 0.58 8.0 29.4 0.072 11.0 17.5 1.5 2 0 0 2 2 2 0 Nop14-like family SAPS PF04499.10 KEP62355.1 - 0.66 8.5 4.9 1.1 7.8 3.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BTV_NS2 PF04514.7 KEP62355.1 - 1.1 8.0 11.9 0.25 10.1 5.9 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 KEP62355.1 - 1.2 8.4 22.8 3 7.1 15.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_polI_A34 PF08208.6 KEP62355.1 - 1.9 8.1 14.8 3.9 7.1 10.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pox_Ag35 PF03286.9 KEP62355.1 - 2.7 7.4 14.1 6.1 6.3 9.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Plasmodium_Vir PF05795.6 KEP62355.1 - 3.4 6.7 4.3 5.5 6.1 3.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.17 KEP62355.1 - 4.5 6.2 5.7 9.1 5.1 4.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.1 KEP62355.1 - 6 5.2 9.2 13 4.1 6.4 1.5 1 0 0 1 1 1 0 Raftlin Helicase_C_2 PF13307.1 KEP62356.1 - 1.1e-47 162.1 0.0 7.4e-47 159.4 0.0 2.5 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEP62356.1 - 1.7e-35 121.9 0.2 2e-30 105.4 0.0 2.4 2 0 0 2 2 2 2 DEAD_2 zf-C3HC4_3 PF13920.1 KEP62356.1 - 4.7e-07 29.3 6.4 1.3e-06 27.9 4.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP62356.1 - 2.9e-06 26.9 8.8 1e-05 25.2 6.1 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEP62356.1 - 3e-05 23.9 8.7 0.00011 22.1 6.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KEP62356.1 - 5.9e-05 22.9 0.0 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEP62356.1 - 0.00011 21.7 0.0 0.013 15.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 KEP62356.1 - 0.00014 21.4 8.0 0.00046 19.7 5.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP62356.1 - 0.00061 19.4 6.8 0.0018 17.9 4.7 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEP62356.1 - 0.0038 17.0 8.3 0.018 14.8 5.7 2.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KEP62356.1 - 0.018 14.6 6.9 0.05 13.2 4.8 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KEP62356.1 - 0.019 14.7 3.1 0.049 13.4 2.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KEP62356.1 - 0.048 13.2 3.7 0.12 11.9 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PhoH PF02562.11 KEP62356.1 - 0.072 12.3 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein zf-rbx1 PF12678.2 KEP62356.1 - 0.84 9.7 8.8 0.086 12.9 2.5 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger AF-4 PF05110.8 KEP62359.1 - 0.011 13.6 8.7 0.012 13.5 6.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SNF2_N PF00176.18 KEP62360.1 - 4.6e-05 22.3 0.0 0.00021 20.2 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF4149 PF13664.1 KEP62361.1 - 4.2e-14 52.4 1.8 4.2e-14 52.4 1.3 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF4149) Ribosomal_L28 PF00830.14 KEP62362.1 - 3.5e-20 71.5 2.0 2.1e-19 69.0 1.0 2.2 2 0 0 2 2 2 1 Ribosomal L28 family RRM_1 PF00076.17 KEP62365.1 - 2.4e-22 78.3 0.0 2.4e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62365.1 - 2.1e-16 59.5 0.0 1.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62365.1 - 2.9e-13 49.5 0.0 7.1e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KEP62365.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Calcipressin DUF4523 PF15023.1 KEP62365.1 - 0.13 11.7 0.0 0.62 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Pex14_N PF04695.8 KEP62366.1 - 0.0039 17.2 1.3 0.0039 17.2 0.9 2.6 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Telomerase_RBD PF12009.3 KEP62368.1 - 2.9e-12 46.6 0.0 5.6e-11 42.5 0.0 2.6 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KEP62368.1 - 0.15 11.3 0.0 2.9 7.1 0.0 2.7 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) BioT2 PF15368.1 KEP62369.1 - 0.085 12.6 0.4 0.085 12.6 0.2 2.2 3 0 0 3 3 3 0 Spermatogenesis family BioT2 Asp PF00026.18 KEP62371.1 - 7.2e-46 156.8 0.0 9e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEP62371.1 - 8.2e-07 29.1 0.1 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEP62371.1 - 0.008 16.6 0.2 1.2 9.6 0.0 3.5 2 2 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 KEP62371.1 - 0.079 12.7 0.1 2 8.3 0.0 2.9 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease DUF2852 PF11014.3 KEP62375.1 - 0.12 12.2 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DGF-1_5 PF11038.3 KEP62375.1 - 0.2 10.8 7.3 0.28 10.3 5.1 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 DUF3481 PF11980.3 KEP62376.1 - 0.059 13.2 7.0 0.13 12.0 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3481) Pox_LP_H2 PF03356.10 KEP62376.1 - 0.7 9.5 7.0 1.5 8.4 0.3 2.0 1 1 1 2 2 2 0 Viral late protein H2 Bac_export_2 PF01312.14 KEP62376.1 - 5.1 5.8 7.0 6.4 5.5 4.8 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family UPF0020 PF01170.13 KEP62377.1 - 2.1e-13 50.2 0.0 2.3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KEP62377.1 - 3.5e-07 30.2 0.0 2.2e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.3 KEP62377.1 - 0.0032 16.5 0.0 3.8 6.4 0.0 3.1 2 1 1 3 3 3 2 RRNA methyltransferase AviRa RNase_T PF00929.19 KEP62378.1 - 8.7e-17 61.8 0.0 1.4e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KEP62378.1 - 0.0031 16.9 0.0 0.0079 15.6 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease FAST_1 PF06743.10 KEP62380.1 - 0.0016 18.0 6.2 0.76 9.5 0.0 5.4 4 1 2 6 6 6 2 FAST kinase-like protein, subdomain 1 PEN-2 PF10251.4 KEP62382.1 - 1.1e-05 25.5 0.1 1.8e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Herpes_capsid PF06112.6 KEP62382.1 - 0.2 11.6 23.0 2.3 8.2 11.1 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Ycf1 PF05758.7 KEP62382.1 - 1.4 6.5 9.1 1.8 6.1 6.3 1.3 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 KEP62382.1 - 2.6 6.3 43.3 0.034 12.6 19.1 2.0 2 0 0 2 2 2 0 Daxx Family WD40 PF00400.27 KEP62383.1 - 5.5e-16 57.7 12.6 6.6e-05 22.6 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat TLD PF07534.11 KEP62392.1 - 2.8e-29 101.9 0.4 8.8e-28 97.0 0.0 2.2 2 0 0 2 2 2 1 TLD Cation_ATPase_N PF00690.21 KEP62392.1 - 0.0015 17.9 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF3619 PF12279.3 KEP62393.1 - 0.095 12.7 1.5 0.3 11.1 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Ribosomal_S4 PF00163.14 KEP62395.1 - 2.1e-08 34.4 2.7 2.6e-08 34.1 1.4 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KEP62395.1 - 1.3e-07 30.9 0.0 2.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain WD40 PF00400.27 KEP62397.1 - 9e-22 76.1 17.1 4.3e-08 32.7 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat FlpD PF02662.11 KEP62397.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Ribosomal_S28e PF01200.13 KEP62398.1 - 3.3e-31 106.8 1.6 4.3e-31 106.4 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e COX5B PF01215.14 KEP62401.1 - 1.2e-11 44.4 0.0 2.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb PAM2 PF07145.10 KEP62402.1 - 0.00036 19.8 2.5 0.0017 17.7 1.8 2.2 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Methyltrans_RNA PF04452.9 KEP62403.1 - 9.6e-43 145.9 0.0 2.8e-23 82.2 0.0 2.1 2 0 0 2 2 2 2 RNA methyltransferase KH_1 PF00013.24 KEP62404.1 - 7.6e-15 54.3 0.0 1.7e-07 30.8 0.0 4.3 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 KEP62404.1 - 4.4e-07 29.3 0.6 0.0042 16.7 0.1 4.2 4 0 0 4 4 4 2 KH domain KH_2 PF07650.12 KEP62404.1 - 0.015 14.8 0.2 0.77 9.3 0.0 3.1 3 0 0 3 3 3 0 KH domain ABC_membrane PF00664.18 KEP62406.1 - 3.2e-32 112.0 3.6 5.9e-32 111.1 2.5 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KEP62406.1 - 2.1e-30 105.8 0.1 1e-29 103.5 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KEP62406.1 - 2.6e-09 37.4 0.5 0.00017 21.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEP62406.1 - 6.4e-06 26.3 1.0 6.2e-05 23.1 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP62406.1 - 5.3e-05 23.2 3.1 0.00036 20.5 2.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KEP62406.1 - 0.00015 21.2 0.2 0.00039 19.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KEP62406.1 - 0.0011 18.4 0.1 0.0032 16.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEP62406.1 - 0.0011 18.1 0.2 0.0028 16.8 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEP62406.1 - 0.0012 19.6 0.5 0.0059 17.4 0.1 2.4 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 KEP62406.1 - 0.0015 17.8 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 KEP62406.1 - 0.0046 16.5 0.7 0.11 12.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain SURF6 PF04935.7 KEP62406.1 - 0.0048 16.2 5.7 0.0092 15.2 4.0 1.4 1 0 0 1 1 1 1 Surfeit locus protein 6 AAA_18 PF13238.1 KEP62406.1 - 0.0092 16.2 1.1 0.02 15.1 0.1 2.1 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KEP62406.1 - 0.01 15.8 1.0 0.08 12.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEP62406.1 - 0.01 16.1 0.1 0.01 16.1 0.0 2.8 2 1 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KEP62406.1 - 0.012 15.5 0.0 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 KEP62406.1 - 0.013 14.0 0.5 0.51 8.8 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class APS_kinase PF01583.15 KEP62406.1 - 0.018 14.6 0.1 0.053 13.1 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_10 PF12846.2 KEP62406.1 - 0.019 14.4 0.1 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain KAP_NTPase PF07693.9 KEP62406.1 - 0.026 13.5 0.0 0.051 12.5 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain SbcCD_C PF13558.1 KEP62406.1 - 0.027 14.3 0.4 0.11 12.4 0.0 2.3 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 KEP62406.1 - 0.032 14.0 0.1 0.094 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 ArgK PF03308.11 KEP62406.1 - 0.034 12.9 0.1 0.07 11.8 0.1 1.4 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 KEP62406.1 - 0.043 13.5 0.2 0.12 12.1 0.1 1.7 2 0 0 2 2 1 0 NTPase Zeta_toxin PF06414.7 KEP62406.1 - 0.06 12.4 0.1 0.06 12.4 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 KEP62406.1 - 0.073 12.7 0.8 0.23 11.0 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.1 KEP62406.1 - 0.09 11.8 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PRK PF00485.13 KEP62406.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 KEP62406.1 - 0.11 12.3 1.9 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PAN_1 PF00024.21 KEP62407.1 - 1.9e-20 72.3 38.1 1.1e-07 31.5 1.7 5.3 2 2 4 6 6 6 4 PAN domain PAN_4 PF14295.1 KEP62407.1 - 3.7e-17 61.7 30.5 3.1e-05 23.5 0.9 5.1 4 1 1 5 5 5 4 PAN domain NMT_C PF02799.10 KEP62409.1 - 3.7e-80 267.7 0.0 6.2e-80 267.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KEP62409.1 - 4.4e-74 247.5 0.1 7.4e-74 246.7 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KEP62409.1 - 4.2e-06 26.6 0.0 1.9e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEP62409.1 - 0.023 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEP62409.1 - 0.071 13.1 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KEP62409.1 - 0.12 12.5 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.9 KEP62410.1 - 3e-22 79.5 0.0 5.2e-22 78.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEP62410.1 - 6.8e-11 42.4 0.0 2.2e-08 34.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEP62410.1 - 0.00064 19.8 0.8 0.26 11.3 0.2 3.3 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DNAPolymera_Pol PF11590.3 KEP62410.1 - 0.0098 15.5 0.0 0.034 13.7 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase catalytic subunit Pol ASF1_hist_chap PF04729.8 KEP62411.1 - 9.9e-72 239.6 0.0 1.2e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RCC1 PF00415.13 KEP62412.1 - 1e-63 211.3 19.8 6.9e-13 48.5 0.1 8.0 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP62412.1 - 5.6e-20 70.4 39.3 1.5e-05 24.4 0.3 7.0 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat TPR_MLP1_2 PF07926.7 KEP62412.1 - 0.038 13.7 4.4 0.058 13.1 3.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 KEP62412.1 - 0.092 12.5 1.3 0.15 11.8 0.9 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF904 PF06005.7 KEP62412.1 - 0.57 10.5 4.1 1 9.6 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) FlxA PF14282.1 KEP62412.1 - 0.92 9.4 6.3 1.8 8.5 4.4 1.3 1 0 0 1 1 1 0 FlxA-like protein UPF0139 PF03669.8 KEP62413.1 - 1.1e-05 24.8 0.1 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) CbiQ PF02361.11 KEP62413.1 - 0.09 12.3 0.8 0.11 12.0 0.6 1.0 1 0 0 1 1 1 0 Cobalt transport protein DUF1440 PF07274.7 KEP62413.1 - 0.1 12.5 0.4 0.12 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) DCP1 PF06058.8 KEP62414.1 - 2.3e-23 82.5 0.0 3.3e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family PUB PF09409.5 KEP62415.1 - 8.3e-15 54.3 0.0 4e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 PUB domain UBX PF00789.15 KEP62415.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 UBX domain UMP1 PF05348.6 KEP62416.1 - 1.1e-15 57.7 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TRAPP PF04051.11 KEP62417.1 - 5.6e-41 139.5 0.0 7.3e-41 139.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PI3K_1B_p101 PF10486.4 KEP62418.1 - 0.0029 15.2 0.7 0.005 14.5 0.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleoplasmin PF03066.10 KEP62418.1 - 1.5 8.2 13.2 0.26 10.7 5.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin TSP_1 PF00090.14 KEP62419.1 - 3.2e-28 97.5 79.2 1.3e-07 31.5 5.0 8.8 8 0 0 8 8 8 8 Thrombospondin type 1 domain Pkinase PF00069.20 KEP62420.1 - 1.1e-48 165.6 0.0 1.6e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP62420.1 - 1.3e-41 142.3 0.0 1.9e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP62420.1 - 0.007 16.1 0.1 1 9.0 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP62420.1 - 0.015 14.2 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KEP62420.1 - 0.047 12.7 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEP62420.1 - 0.34 10.2 0.0 0.6 9.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF4201 PF13870.1 KEP62422.1 - 1.2e-14 54.1 24.2 4.2e-14 52.3 5.2 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) APG6 PF04111.7 KEP62422.1 - 0.014 14.4 23.9 0.22 10.5 9.6 2.5 2 1 0 2 2 2 0 Autophagy protein Apg6 EFP PF01132.15 KEP62422.1 - 0.021 14.4 4.9 0.18 11.4 0.2 2.4 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain LPP PF04728.8 KEP62422.1 - 0.072 12.9 1.5 0.78 9.5 0.1 2.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper RE_LlaMI PF09562.5 KEP62422.1 - 0.086 11.9 0.1 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 LlaMI restriction endonuclease Fes1 PF08609.5 KEP62422.1 - 0.77 10.2 13.1 1 9.9 0.5 2.8 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 Methyltransf_14 PF08484.6 KEP62422.1 - 1.5 8.3 4.3 0.86 9.1 0.6 2.2 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain RasGAP_C PF03836.10 KEP62422.1 - 4.5 6.9 15.5 0.7 9.5 1.7 3.1 2 1 1 3 3 3 0 RasGAP C-terminus Cep57_CLD_2 PF14197.1 KEP62422.1 - 5.7 6.9 20.6 1.4 8.8 0.1 3.8 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DivIVA PF05103.8 KEP62422.1 - 6.8 6.7 26.5 0.5 10.4 0.5 3.8 2 1 1 3 3 3 0 DivIVA protein Rho_Binding PF08912.6 KEP62422.1 - 7.8 6.8 27.1 0.56 10.5 1.6 4.3 4 1 0 4 4 4 0 Rho Binding CENP-F_leu_zip PF10473.4 KEP62422.1 - 8.2 6.2 32.8 0.3 10.9 1.6 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Actin PF00022.14 KEP62423.1 - 1.1e-154 514.5 0.0 1.3e-154 514.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KEP62423.1 - 0.11 12.8 0.0 0.34 11.3 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EF_TS PF00889.14 KEP62425.1 - 3.7e-27 95.0 0.0 2.4e-15 56.4 0.0 2.6 2 1 0 2 2 2 2 Elongation factor TS UBA PF00627.26 KEP62425.1 - 1.7e-06 27.6 0.3 9.1e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain HECT PF00632.20 KEP62426.1 - 3.3e-45 154.6 0.0 5.5e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_5 PF13857.1 KEP62426.1 - 7.2e-11 41.9 0.6 1.3e-05 25.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KEP62426.1 - 8.2e-11 41.1 0.0 0.0003 20.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KEP62426.1 - 2.1e-10 40.8 0.0 1.7e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP62426.1 - 8e-07 29.4 0.0 0.074 13.5 0.0 4.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP62426.1 - 0.0043 17.1 0.0 2.9 8.4 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat MAM PF00629.18 KEP62426.1 - 7 6.3 0.7 65 3.2 0.1 2.4 2 0 0 2 2 2 0 MAM domain G-patch_2 PF12656.2 KEP62427.1 - 4.3e-17 61.7 0.5 1.3e-16 60.1 0.4 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site Amnionless PF14828.1 KEP62428.1 - 0.06 11.8 0.3 0.074 11.5 0.2 1.1 1 0 0 1 1 1 0 Amnionless RRM_1 PF00076.17 KEP62429.1 - 3.5e-15 55.3 0.0 5.6e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62429.1 - 4.2e-15 55.4 0.0 7.1e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62429.1 - 2.3e-06 27.3 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAG PF04092.8 KEP62431.1 - 1.7e-13 51.0 8.5 2e-13 50.8 5.9 1.1 1 0 0 1 1 1 1 SRS domain zf-RING_3 PF14369.1 KEP62431.1 - 0.11 12.4 0.5 3.4 7.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger DEAD PF00270.24 KEP62432.1 - 1.2e-19 70.4 0.0 6.5e-17 61.5 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62432.1 - 2.2e-14 53.0 0.0 7.2e-14 51.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP62432.1 - 4.1e-07 30.0 0.0 7.7e-06 25.8 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KEP62432.1 - 0.00058 19.5 0.1 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain SecA_DEAD PF07517.9 KEP62432.1 - 0.011 14.9 0.2 0.059 12.6 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain Zot PF05707.7 KEP62432.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) RC-P840_PscD PF10657.4 KEP62432.1 - 0.095 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD UPF0079 PF02367.12 KEP62432.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Nucleo_P87 PF07267.6 KEP62432.1 - 1.1 7.8 0.8 2.3 6.7 0.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DXP_synthase_N PF13292.1 KEP62434.1 - 3.2e-88 295.1 0.0 5.9e-76 254.9 0.0 2.4 2 0 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 KEP62434.1 - 2.2e-42 144.5 0.0 4.3e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEP62434.1 - 9.6e-21 73.9 0.0 9.1e-19 67.6 0.0 2.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 KEP62434.1 - 3.3e-08 32.7 0.2 0.0056 15.5 0.1 2.4 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.15 KEP62434.1 - 0.0063 15.2 0.1 0.016 13.9 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component TPR_19 PF14559.1 KEP62435.1 - 1.7e-12 47.4 1.5 4.4e-07 30.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEP62435.1 - 9.2e-11 41.2 0.9 1.9e-06 27.4 0.2 2.9 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEP62435.1 - 1.1e-09 37.4 0.3 0.00045 19.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP62435.1 - 8.3e-08 32.0 5.9 1.8e-05 24.6 0.1 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP62435.1 - 4.2e-07 29.2 0.3 0.00021 20.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62435.1 - 5.8e-07 30.0 1.7 1.8e-06 28.4 0.0 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62435.1 - 4.1e-06 26.9 0.7 0.085 13.5 0.0 3.3 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62435.1 - 6.1e-06 25.6 0.0 0.00012 21.6 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP62435.1 - 0.00029 20.4 2.5 0.019 14.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEP62435.1 - 0.00032 20.9 0.9 0.0023 18.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEP62435.1 - 0.00043 20.1 0.1 0.74 9.7 0.0 2.6 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat Sec16_C PF12931.2 KEP62435.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_4 PF07721.9 KEP62435.1 - 0.026 14.9 2.9 1.9 9.1 0.0 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat FKBP_C PF00254.23 KEP62435.1 - 0.033 14.1 0.0 0.093 12.7 0.0 1.7 2 0 0 2 2 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Apc3 PF12895.2 KEP62435.1 - 0.12 12.5 0.2 2.2 8.4 0.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Mito_carr PF00153.22 KEP62437.1 - 9.6e-19 66.9 4.7 1.1e-07 31.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.21 KEP62438.1 - 1.5e-44 150.7 0.0 1.9e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEP62438.1 - 0.053 13.4 0.1 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 KEP62438.1 - 0.06 13.1 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B cEGF PF12662.2 KEP62440.1 - 0.014 15.0 6.5 3.3 7.4 0.1 4.9 5 0 0 5 5 5 0 Complement Clr-like EGF-like RWD PF05773.17 KEP62441.1 - 1.7e-14 53.6 0.5 2.5e-14 53.1 0.4 1.3 1 0 0 1 1 1 1 RWD domain MAR_sialic_bdg PF10564.4 KEP62442.1 - 4.4e-51 170.7 22.6 7.4e-24 83.3 3.3 4.3 3 1 1 4 4 4 4 Sialic-acid binding micronemal adhesive repeat DUF842 PF05811.8 KEP62442.1 - 0.15 11.5 4.6 16 4.9 0.0 3.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) MAR_sialic_bdg PF10564.4 KEP62443.1 - 9.3e-48 160.0 26.5 1.2e-22 79.4 1.6 4.3 3 1 1 4 4 4 4 Sialic-acid binding micronemal adhesive repeat DSPc PF00782.15 KEP62444.1 - 2.1e-07 30.5 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEP62444.1 - 7.6e-06 25.4 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEP62444.1 - 0.00088 19.3 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Endonuclease_NS PF01223.18 KEP62445.1 - 8.1e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.18 KEP62446.1 - 3.1e-07 30.2 0.0 2.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 DNA/RNA non-specific endonuclease V-ATPase_H_C PF11698.3 KEP62447.1 - 2.4e-47 159.7 1.4 5.7e-47 158.5 0.3 2.1 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 KEP62447.1 - 2.1e-38 132.1 0.0 3.8e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H Adaptin_N PF01602.15 KEP62447.1 - 0.0052 15.1 0.0 3.9 5.6 0.0 3.1 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 KEP62447.1 - 0.0066 15.5 0.3 0.32 10.0 0.0 2.8 2 1 1 3 3 3 1 Armadillo-like HEAT_EZ PF13513.1 KEP62447.1 - 0.25 11.9 3.9 12 6.4 0.2 4.1 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.1 KEP62447.1 - 0.95 9.7 5.8 3.7 7.8 0.0 3.6 4 1 1 5 5 5 0 HEAT repeats DNA_ligase_A_M PF01068.16 KEP62448.1 - 8.4e-51 172.2 0.0 4.1e-42 143.8 0.0 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEP62448.1 - 1.4e-37 129.2 0.8 2.2e-37 128.5 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEP62448.1 - 1.2e-21 76.8 0.0 3.8e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region UQ_con PF00179.21 KEP62449.1 - 2.3e-21 75.7 0.0 3.7e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mito_carr PF00153.22 KEP62450.1 - 5.1e-15 54.9 0.2 7.5e-05 22.3 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2951 PF11166.3 KEP62451.1 - 1.3 8.8 9.9 1.5 8.6 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DEAD PF00270.24 KEP62452.1 - 4.1e-38 130.5 0.1 2.1e-37 128.2 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62452.1 - 1.3e-21 76.2 0.0 2.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEP62452.1 - 2.5e-05 23.2 0.0 5.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBP10CT PF08147.7 KEP62452.1 - 0.0019 17.9 6.2 0.0019 17.9 4.3 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.10 KEP62452.1 - 0.011 15.6 0.0 0.032 14.0 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DsrH PF04077.7 KEP62452.1 - 0.071 12.7 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 DsrH like protein CagX PF03524.10 KEP62453.1 - 0.19 11.0 1.1 0.22 10.7 0.8 1.1 1 0 0 1 1 1 0 Conjugal transfer protein NAPRTase PF04095.11 KEP62454.1 - 5.1e-20 71.7 0.0 6.2e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.11 KEP62454.1 - 0.12 12.2 0.0 0.43 10.4 0.0 2.0 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain PP2C PF00481.16 KEP62456.1 - 3.8e-53 180.4 0.1 6.4e-49 166.6 0.0 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C MMR_HSR1 PF01926.18 KEP62457.1 - 9.6e-16 57.7 0.1 5.3e-14 52.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP62457.1 - 8e-06 25.2 0.1 0.00022 20.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KEP62457.1 - 0.0077 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KEP62457.1 - 0.066 13.7 0.0 0.35 11.3 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein HNOBA PF07701.9 KEP62457.1 - 3.1 6.9 11.4 0.3 10.2 0.1 3.0 3 0 0 3 3 3 0 Heme NO binding associated Kazal_1 PF00050.16 KEP62458.1 - 4.4e-25 87.4 38.5 1.3e-06 28.2 2.6 4.4 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KEP62458.1 - 3.2e-09 36.5 40.5 0.014 15.3 2.4 4.8 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain DUF3012 PF11216.3 KEP62458.1 - 0.11 12.1 1.0 5.3 6.8 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3012) IFR3_antag PF14754.1 KEP62458.1 - 8.6 5.2 23.2 0.33 9.9 1.9 3.5 4 0 0 4 4 4 0 Papain-like auto-proteinase Kazal_1 PF00050.16 KEP62460.1 - 1.1e-23 82.9 45.2 5.4e-08 32.7 4.8 4.5 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KEP62460.1 - 1.5e-18 66.4 33.6 4.7e-06 26.4 4.8 4.8 4 2 0 4 4 4 4 Kazal-type serine protease inhibitor domain IFR3_antag PF14754.1 KEP62460.1 - 2.4 7.0 14.7 1.2 8.0 1.6 3.1 2 1 1 3 3 3 0 Papain-like auto-proteinase DUF2799 PF10973.3 KEP62460.1 - 7.1 6.7 16.6 19 5.3 1.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2799) SNF PF00209.13 KEP62461.1 - 4.2e-26 91.5 33.6 4.2e-26 91.5 23.3 1.8 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family SNF PF00209.13 KEP62462.1 - 9.9e-22 77.0 18.6 9.9e-22 77.0 12.9 1.7 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family F-actin_cap_A PF01267.12 KEP62464.1 - 3.9e-17 62.2 0.0 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 F-actin capping protein alpha subunit CortBP2 PF09727.4 KEP62464.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Cortactin-binding protein-2 Spc97_Spc98 PF04130.8 KEP62466.1 - 0.0057 15.0 1.9 0.63 8.2 0.3 2.6 2 0 0 2 2 2 2 Spc97 / Spc98 family RRM_6 PF14259.1 KEP62468.1 - 1.9e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP62468.1 - 2.4e-05 23.8 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62468.1 - 0.031 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2981 PF11200.3 KEP62470.1 - 6.9e-18 64.7 0.6 1.7e-14 53.6 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF2981) Tetraspannin PF00335.15 KEP62470.1 - 0.00029 20.2 0.2 0.00029 20.2 0.2 2.1 2 0 0 2 2 2 1 Tetraspanin family DUF4199 PF13858.1 KEP62470.1 - 1.1 9.0 8.1 1.2 8.9 3.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) PNK3P PF08645.6 KEP62471.1 - 1.3e-39 135.1 0.0 7.5e-25 87.2 0.0 2.3 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KEP62471.1 - 1.6e-17 63.6 0.2 6.9e-17 61.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEP62471.1 - 9e-06 24.9 0.2 0.00017 20.7 0.1 2.2 1 1 1 2 2 2 2 Zeta toxin AAA_16 PF13191.1 KEP62471.1 - 0.0003 20.8 0.1 0.0009 19.2 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 KEP62471.1 - 0.00084 19.4 0.2 0.0033 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEP62471.1 - 0.0039 17.4 0.0 0.0069 16.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 KEP62471.1 - 0.0053 17.5 0.1 0.021 15.6 0.1 2.0 2 1 0 2 2 1 1 AAA domain NB-ARC PF00931.17 KEP62471.1 - 0.0093 14.8 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.1 KEP62471.1 - 0.021 14.3 0.0 0.067 12.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KEP62471.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEP62471.1 - 0.048 13.6 0.3 0.12 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEP62471.1 - 0.064 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 KEP62471.1 - 0.094 12.1 0.1 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KEP62471.1 - 0.1 12.8 1.1 0.32 11.3 0.7 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEP62471.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KEP62471.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEP62471.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 KEP62471.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 KEP62471.1 - 0.16 12.1 0.2 0.47 10.6 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 KEP62471.1 - 0.21 10.7 4.7 0.39 9.8 0.1 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 FHA PF00498.21 KEP62472.1 - 3e-08 33.6 0.0 7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain CHCH PF06747.8 KEP62473.1 - 5.4e-05 22.9 4.3 6.4e-05 22.7 2.5 1.5 2 0 0 2 2 2 1 CHCH domain DUF1903 PF08991.5 KEP62473.1 - 0.019 15.1 1.9 0.031 14.4 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) PHD PF00628.24 KEP62474.1 - 1e-10 41.1 14.4 2.2e-10 40.0 10.0 1.6 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KEP62474.1 - 6e-06 26.4 0.5 8.3e-06 26.0 0.3 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 KEP62474.1 - 0.012 14.8 7.9 0.023 14.0 5.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 KEP62474.1 - 0.02 14.7 10.7 0.036 13.9 7.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-PHD-like PF15446.1 KEP62474.1 - 0.16 11.2 5.1 0.25 10.6 3.5 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PHF5 PF03660.9 KEP62474.1 - 0.18 11.9 4.2 0.32 11.0 2.9 1.3 1 0 0 1 1 1 0 PHF5-like protein Prok-RING_1 PF14446.1 KEP62474.1 - 1.1 9.0 11.2 0.39 10.4 4.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 KEP62474.1 - 6.1 6.9 10.1 11 6.0 7.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 5-FTHF_cyc-lig PF01812.15 KEP62475.1 - 2.1e-22 79.8 0.7 2e-16 60.3 0.0 2.7 3 0 0 3 3 3 2 5-formyltetrahydrofolate cyclo-ligase family Med15 PF09606.5 KEP62475.1 - 0.79 7.8 11.2 1.1 7.4 7.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal IPK PF03770.11 KEP62476.1 - 8.6e-51 172.3 0.0 1.5e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase ABC_tran PF00005.22 KEP62477.1 - 4.6e-23 82.0 0.0 8.7e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEP62477.1 - 3.4e-15 56.2 0.0 4.7e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Zeta_toxin PF06414.7 KEP62477.1 - 0.0037 16.4 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.1 KEP62477.1 - 0.026 14.4 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEP62477.1 - 0.031 13.8 0.1 0.098 12.2 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEP62477.1 - 0.049 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KEP62479.1 - 3.7e-16 59.6 0.0 8.5e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEP62479.1 - 2e-05 24.1 1.0 3.9e-05 23.2 0.1 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region DUF258 PF03193.11 KEP62479.1 - 0.0009 18.4 0.1 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEP62479.1 - 0.011 15.1 0.3 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEP62479.1 - 0.043 13.3 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 KEP62479.1 - 0.18 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_21 PF13304.1 KEP62479.1 - 0.27 11.1 0.1 0.52 10.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEP62479.1 - 0.37 10.1 0.0 0.58 9.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Aldo_ket_red PF00248.16 KEP62480.1 - 1.3e-59 201.3 0.0 2e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family PAN_1 PF00024.21 KEP62481.1 - 2.5e-39 132.8 44.4 1.5e-08 34.2 1.0 6.3 3 3 3 6 6 6 6 PAN domain PAN_4 PF14295.1 KEP62481.1 - 5.5e-36 122.0 34.3 6.5e-07 28.9 0.8 6.8 6 0 0 6 6 6 6 PAN domain PAN_2 PF08276.6 KEP62481.1 - 1.7e-07 30.9 46.9 0.012 15.4 0.3 7.2 6 3 1 7 7 7 5 PAN-like domain PAN_3 PF08277.7 KEP62481.1 - 3.7e-05 23.2 29.2 0.2 11.3 0.1 6.6 6 0 0 6 6 6 4 PAN-like domain POLO_box PF00659.13 KEP62481.1 - 0.15 12.0 0.2 6.8 6.7 0.0 2.7 2 0 0 2 2 2 0 POLO box duplicated region AP2 PF00847.15 KEP62482.1 - 7.9e-13 48.3 6.8 3.2e-08 33.6 0.4 3.1 3 0 0 3 3 3 2 AP2 domain Use1 PF09753.4 KEP62483.1 - 5e-05 22.8 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec2p PF06428.6 KEP62483.1 - 0.073 12.9 0.3 0.92 9.3 0.0 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Spb1_C PF07780.7 KEP62484.1 - 2.5e-66 223.2 23.6 2.5e-66 223.2 16.3 3.6 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 KEP62484.1 - 2.8e-57 193.6 0.2 4.8e-57 192.8 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KEP62484.1 - 8e-20 70.9 0.8 8e-20 70.9 0.5 6.0 6 1 1 7 7 7 2 Domain of unknown function (DUF3381) PIG-P PF08510.7 KEP62485.1 - 6.2e-33 113.1 1.0 9.7e-33 112.4 0.7 1.3 1 0 0 1 1 1 1 PIG-P HEAT_2 PF13646.1 KEP62486.1 - 1.5e-05 25.1 16.3 0.051 13.8 0.9 6.3 5 1 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 KEP62486.1 - 0.0019 18.6 20.3 0.11 13.0 0.3 7.0 8 0 0 8 8 8 3 HEAT-like repeat HEAT PF02985.17 KEP62486.1 - 0.034 14.2 28.2 0.2 11.8 0.2 7.6 8 0 0 8 8 8 0 HEAT repeat Vac14_Fab1_bd PF12755.2 KEP62486.1 - 2.3 8.6 4.7 34 4.8 0.0 4.4 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KEP62486.1 - 7.2 6.4 6.2 43 3.8 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 FAD_binding_3 PF01494.14 KEP62487.1 - 8.5e-08 31.6 0.4 0.075 12.0 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 KEP62487.1 - 3.2e-06 26.2 0.4 5e-06 25.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEP62487.1 - 1.2e-05 24.4 0.1 2.6e-05 23.3 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEP62487.1 - 6.9e-05 22.8 0.5 0.00019 21.3 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KEP62487.1 - 0.00029 19.8 0.1 0.00045 19.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KEP62487.1 - 0.00055 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEP62487.1 - 0.0039 15.7 0.3 0.0068 14.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KEP62487.1 - 0.04 13.0 0.8 0.07 12.2 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEP62487.1 - 0.04 12.8 0.2 0.11 11.3 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 KEP62487.1 - 0.045 12.8 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family VitD-bind_III PF09164.5 KEP62487.1 - 0.077 12.6 0.7 0.22 11.1 0.2 2.0 2 0 0 2 2 2 0 Vitamin D binding protein, domain III DUF3315 PF11776.3 KEP62487.1 - 0.095 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) DUF1712 PF08217.6 KEP62488.1 - 4.3e-25 88.0 0.0 8.6e-24 83.7 0.0 2.3 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) Epiglycanin_C PF14654.1 KEP62490.1 - 0.066 13.2 0.8 0.38 10.7 0.1 2.0 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region KNOX2 PF03791.8 KEP62490.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 KNOX2 domain Phage_Coat_Gp8 PF05371.7 KEP62490.1 - 0.083 12.4 0.6 0.16 11.5 0.4 1.4 1 0 0 1 1 1 0 Phage major coat protein, Gp8 zf-LITAF-like PF10601.4 KEP62490.1 - 1.7 8.5 15.5 7.5 6.5 6.0 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Ribosomal_S9 PF00380.14 KEP62491.1 - 1.9e-30 105.5 0.0 2.7e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PBP PF01161.15 KEP62492.1 - 9.4e-20 70.9 0.1 1.2e-19 70.5 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Na_Ca_ex PF01699.19 KEP62494.1 - 2e-39 134.3 28.9 2.7e-21 75.6 7.9 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3366 PF11846.3 KEP62494.1 - 0.34 10.7 3.1 8 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) MIG-14_Wnt-bd PF06664.7 KEP62494.1 - 0.6 8.8 8.4 1.5 7.6 5.8 1.8 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion TFIIB PF00382.14 KEP62495.1 - 2.7e-23 81.5 0.5 1.9e-10 40.3 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KEP62495.1 - 7.7e-19 67.7 0.4 7.7e-19 67.7 0.3 2.0 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 KEP62495.1 - 2.7e-08 32.9 1.9 5.3e-08 32.0 1.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Crp_2 PF13545.1 KEP62495.1 - 0.014 15.1 0.9 0.026 14.2 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.1 KEP62495.1 - 0.032 13.6 0.1 0.21 10.9 0.0 2.3 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding NHL PF01436.16 KEP62497.1 - 3.5e-14 51.9 0.2 0.0011 18.8 0.0 4.4 3 0 0 3 3 3 3 NHL repeat GCC2_GCC3 PF07699.8 KEP62497.1 - 1.8e-08 33.8 538.6 0.00087 18.8 2.1 50.0 34 10 15 49 49 49 24 GCC2 and GCC3 SGL PF08450.7 KEP62497.1 - 0.00069 19.0 0.0 0.002 17.5 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 KEP62497.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller RcsC PF09456.5 KEP62497.1 - 0.92 9.1 0.0 2 8.1 0.0 1.5 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) Arylesterase PF01731.15 KEP62497.1 - 4 7.4 0.0 8.5 6.4 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Ribosomal_S17e PF00833.13 KEP62498.1 - 1.5e-59 199.1 1.1 1.6e-59 198.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal S17 MORN PF02493.15 KEP62499.1 - 6.1e-49 160.9 52.5 1.9e-07 30.3 0.0 10.3 10 0 0 10 10 10 10 MORN repeat Pkinase PF00069.20 KEP62500.1 - 3.3e-61 206.6 0.0 6.6e-61 205.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP62500.1 - 1.7e-28 99.3 0.0 4.6e-23 81.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEP62500.1 - 0.12 12.0 1.6 0.19 11.4 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KEP62501.1 - 0.21 10.6 0.8 0.31 10.0 0.1 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Enkurin PF13864.1 KEP62502.1 - 5e-27 93.9 0.2 6.5e-27 93.6 0.2 1.1 1 0 0 1 1 1 1 Calmodulin-binding DUF2986 PF11661.3 KEP62502.1 - 0.19 12.1 1.3 2.6 8.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Cupin_6 PF12852.2 KEP62504.1 - 0.093 12.3 0.0 0.094 12.3 0.0 1.1 1 0 0 1 1 1 0 Cupin PCI PF01399.22 KEP62505.1 - 2.6e-12 47.0 0.2 6.2e-09 36.1 0.0 2.8 3 0 0 3 3 3 2 PCI domain DUF1543 PF07566.7 KEP62505.1 - 0.72 9.4 3.8 3 7.4 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1543) CTDII PF01556.13 KEP62506.1 - 5.2e-27 93.5 4.8 1.9e-19 69.2 0.1 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 KEP62506.1 - 7.2e-23 80.1 0.7 1.3e-22 79.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KEP62506.1 - 1.4e-08 34.6 16.6 1.4e-08 34.6 11.5 2.2 3 0 0 3 3 3 1 DnaJ central domain CAP_N PF01213.14 KEP62506.1 - 0.45 9.7 8.7 0.78 8.9 6.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_transf_17 PF04724.8 KEP62507.1 - 4.2e-15 55.6 2.0 1.5e-13 50.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 17 DUF4626 PF15422.1 KEP62507.1 - 0.14 12.0 4.9 0.29 11.0 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4626) SLS PF14611.1 KEP62509.1 - 0.042 13.2 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Nrap PF03813.9 KEP62510.1 - 4.7e-85 285.9 0.0 9.2e-34 116.1 0.0 6.0 4 2 0 4 4 4 4 Nrap protein CDP-OH_P_transf PF01066.16 KEP62511.1 - 2.9e-15 56.3 14.0 1.1e-14 54.4 9.7 2.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase EmrE PF13536.1 KEP62511.1 - 4.7 7.4 10.9 0.91 9.7 4.2 2.2 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Kinase-like PF14531.1 KEP62512.1 - 1.7e-14 53.4 0.0 4.1e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP62512.1 - 2.3e-07 30.2 0.1 6.6e-07 28.7 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain BRK PF07533.11 KEP62512.1 - 0.025 14.0 0.1 0.075 12.5 0.1 1.7 2 0 0 2 2 2 0 BRK domain dsDNA_bind PF01984.15 KEP62513.1 - 9.2e-25 86.7 7.6 1.1e-24 86.5 5.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF3395 PF11875.3 KEP62513.1 - 0.81 9.3 4.5 0.93 9.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Skp1 PF01466.14 KEP62514.1 - 3.8e-35 119.7 1.0 6e-35 119.1 0.7 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KEP62514.1 - 7.5e-20 70.7 1.6 1.4e-19 69.8 1.1 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 KEP62514.1 - 0.0055 16.6 0.1 0.018 15.0 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain Kinesin PF00225.18 KEP62515.1 - 3.6e-106 354.6 0.5 3.6e-106 354.6 0.4 1.5 2 0 0 2 2 2 1 Kinesin motor domain PIF1 PF05970.9 KEP62515.1 - 0.0051 15.8 0.2 0.01 14.8 0.1 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_22 PF13401.1 KEP62515.1 - 0.087 12.9 2.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain OTU PF02338.14 KEP62516.1 - 3.5e-11 43.7 0.0 1.7e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease tRNA-synt_1 PF00133.17 KEP62519.1 - 2.1e-217 722.9 0.0 3e-217 722.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEP62519.1 - 1.2e-24 86.8 0.1 5e-24 84.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEP62519.1 - 6.1e-17 61.3 1.4 1.2e-06 27.5 0.2 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KEP62519.1 - 0.0075 15.4 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RF-1 PF00472.15 KEP62520.1 - 1.4e-31 108.6 2.6 1.4e-31 108.6 1.8 2.8 3 0 0 3 3 3 1 RF-1 domain PCRF PF03462.13 KEP62520.1 - 1.5e-19 69.7 0.1 1.4e-17 63.4 0.1 2.7 2 0 0 2 2 2 1 PCRF domain UNC-93 PF05978.11 KEP62520.1 - 1.8 8.0 8.8 3.2 7.2 6.1 1.3 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Pyr_redox_2 PF07992.9 KEP62521.1 - 8.8e-21 74.7 0.0 2.2e-20 73.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KEP62521.1 - 1e-15 57.0 0.0 2.1e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KEP62521.1 - 5.5e-13 49.1 1.5 4.6e-10 39.7 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KEP62521.1 - 3.9e-12 45.8 0.0 2.4e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 KEP62521.1 - 6.2e-08 32.8 0.0 3.8e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Reductase C-terminal DAO PF01266.19 KEP62521.1 - 1.6e-07 30.5 4.9 9.1e-06 24.8 0.0 3.9 5 0 0 5 5 5 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEP62521.1 - 3.2e-05 24.0 0.0 0.0025 17.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KEP62521.1 - 0.016 14.9 0.6 0.14 11.9 0.1 2.6 2 1 0 2 2 2 0 ThiF family HMA PF00403.21 KEP62521.1 - 0.025 14.7 3.4 0.095 12.8 0.0 3.1 4 0 0 4 4 4 0 Heavy-metal-associated domain Shikimate_DH PF01488.15 KEP62521.1 - 0.038 14.1 1.1 7.1 6.7 0.1 2.7 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KEP62521.1 - 0.038 12.4 0.2 0.84 8.0 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.1 KEP62521.1 - 0.085 12.8 1.2 1.9 8.5 0.2 3.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Kinase-like PF14531.1 KEP62522.1 - 2e-24 86.0 0.0 3.1e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP62522.1 - 2.1e-06 27.1 0.0 4.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP62522.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Tubulin PF00091.20 KEP62523.1 - 9.5e-34 117.0 0.0 2.4e-24 86.3 0.0 3.1 3 0 0 3 3 3 3 Tubulin/FtsZ family, GTPase domain PP2C PF00481.16 KEP62524.1 - 3.7e-08 33.0 0.0 1.3e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEP62524.1 - 1.6e-05 24.4 0.0 4.2e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEP62524.1 - 0.0024 17.6 0.0 0.025 14.2 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) GCC2_GCC3 PF07699.8 KEP62525.1 - 7.3e-28 95.9 423.6 3.3e-06 26.5 1.2 41.3 32 6 10 42 42 42 28 GCC2 and GCC3 SNF2_N PF00176.18 KEP62525.1 - 2.1 7.0 2.8 5 5.8 1.9 1.6 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ras PF00071.17 KEP62527.1 - 1.1e-44 151.6 0.0 1.4e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP62527.1 - 1.6e-17 64.0 0.0 2.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP62527.1 - 3.2e-13 49.3 0.0 4.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEP62527.1 - 5.4e-06 25.9 0.0 1e-05 25.0 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEP62527.1 - 8.8e-05 21.7 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEP62527.1 - 0.0034 17.3 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KEP62527.1 - 0.0043 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KEP62527.1 - 0.006 15.7 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEP62527.1 - 0.066 13.3 0.0 0.41 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KEP62527.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEP62527.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KEP62527.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEP62527.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.7 KEP62527.1 - 0.098 11.9 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.1 KEP62527.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RtcB PF01139.12 KEP62528.1 - 1.1e-144 482.5 0.1 1.4e-144 482.2 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB ACP_syn_III_C PF08541.5 KEP62528.1 - 0.0024 17.8 0.0 0.0088 16.0 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ribosomal_S4e PF00900.15 KEP62529.1 - 1.1e-30 105.1 0.0 3.1e-30 103.6 0.0 1.8 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KEP62529.1 - 4.7e-19 67.9 8.1 4.7e-19 67.9 5.6 2.2 3 0 0 3 3 3 1 RS4NT (NUC023) domain S4 PF01479.20 KEP62529.1 - 5.7e-07 28.8 0.1 1.3e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KEP62529.1 - 5.3e-05 22.7 1.0 5.3e-05 22.7 0.7 2.5 3 0 0 3 3 3 1 KOW motif DEAD PF00270.24 KEP62530.1 - 1.1e-40 138.8 0.0 1.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62530.1 - 1.3e-17 63.3 0.0 2.8e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.23 KEP62530.1 - 1e-16 61.1 0.0 1.7e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain TPR_11 PF13414.1 KEP62532.1 - 4.2e-26 90.3 21.6 1.9e-07 30.6 0.2 6.8 4 2 3 8 8 8 5 TPR repeat TPR_2 PF07719.12 KEP62532.1 - 6.3e-25 85.0 20.9 0.0054 16.5 0.1 9.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 KEP62532.1 - 1.5e-23 82.4 17.0 1.8e-08 34.2 0.2 6.2 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KEP62532.1 - 4.3e-23 79.9 9.1 0.0022 17.5 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62532.1 - 1.4e-20 73.3 16.0 6.2e-05 23.5 0.4 6.8 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62532.1 - 3e-14 52.2 11.7 0.25 12.1 0.0 8.6 5 3 4 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62532.1 - 2.1e-12 45.8 9.8 0.35 10.7 0.0 8.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEP62532.1 - 5.3e-12 44.5 9.3 0.036 13.8 0.0 7.8 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEP62532.1 - 4e-11 42.6 9.7 0.94 10.0 0.1 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEP62532.1 - 1.1e-10 41.6 16.2 0.031 14.6 0.0 5.6 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_10 PF13374.1 KEP62532.1 - 1.3e-07 31.3 9.2 0.048 13.6 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KEP62532.1 - 7.1e-07 29.2 20.9 0.0019 18.3 1.1 5.1 5 1 1 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KEP62532.1 - 4.1e-06 26.5 1.3 13 6.3 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEP62532.1 - 0.0018 18.0 8.4 7.7 6.4 0.2 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 KEP62532.1 - 0.0059 16.5 3.6 0.61 10.0 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEP62532.1 - 0.011 16.0 0.1 27 5.5 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat RPN7 PF10602.4 KEP62532.1 - 0.079 12.3 0.4 12 5.2 0.0 3.3 3 1 1 4 4 4 0 26S proteasome subunit RPN7 DUF572 PF04502.8 KEP62535.1 - 2.5e-90 303.0 18.9 4.5e-90 302.1 12.0 1.9 1 1 1 2 2 2 1 Family of unknown function (DUF572) Adap_comp_sub PF00928.16 KEP62536.1 - 1.2e-60 204.8 0.0 1.6e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEP62536.1 - 3.6e-06 26.7 0.0 6.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Reo_sigmaC PF04582.7 KEP62537.1 - 1 8.4 9.7 0.051 12.7 0.8 2.6 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF948 PF06103.6 KEP62537.1 - 1.5 8.6 5.3 0.6 10.0 1.5 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Allexi_40kDa PF05549.6 KEP62537.1 - 2.3 7.4 12.5 0.87 8.8 6.2 2.0 1 1 0 2 2 2 0 Allexivirus 40kDa protein Vps51 PF08700.6 KEP62537.1 - 4.4 7.2 15.0 0.12 12.2 2.1 3.2 2 1 1 3 3 3 0 Vps51/Vps67 Macoilin PF09726.4 KEP62537.1 - 6.2 4.9 21.9 14 3.7 15.2 1.6 1 0 0 1 1 1 0 Transmembrane protein DUF4239 PF14023.1 KEP62537.1 - 7.3 5.9 8.7 15 4.8 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3661 PF12400.3 KEP62543.1 - 1e-35 122.6 5.6 1.4e-35 122.1 3.9 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein DUF4381 PF14316.1 KEP62543.1 - 0.42 10.7 0.1 0.42 10.7 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) RNase_Zc3h12a PF11977.3 KEP62544.1 - 0.00011 22.1 0.0 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 Zc3h12a-like Ribonuclease NYN domain RAB3GAP2_C PF14656.1 KEP62544.1 - 0.84 7.6 0.1 1.3 7.0 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus SpoIIE PF07228.7 KEP62547.1 - 4.4e-06 26.5 0.1 0.12 12.1 0.1 2.6 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KEP62547.1 - 0.032 13.6 0.1 0.86 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C Pkinase PF00069.20 KEP62548.1 - 2.4e-64 217.0 0.0 3.7e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP62548.1 - 4.6e-26 91.4 0.0 7.5e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP62548.1 - 1.5e-05 24.0 0.0 4.7e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like GBP PF02263.14 KEP62550.1 - 5e-25 88.0 0.0 2.2e-19 69.5 0.0 3.3 2 1 0 2 2 2 2 Guanylate-binding protein, N-terminal domain SICA_alpha PF12887.2 KEP62550.1 - 0.57 9.9 13.2 0.095 12.4 1.9 3.5 3 0 0 3 3 3 0 SICA extracellular alpha domain DIT1_PvcA PF05141.7 KEP62550.1 - 2.6 7.3 13.0 0.044 13.1 3.6 1.9 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein CDC45 PF02724.9 KEP62551.1 - 0.071 11.1 1.7 0.098 10.6 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Cep57_CLD_2 PF14197.1 KEP62551.1 - 0.083 12.8 5.4 0.14 12.1 3.4 1.7 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 NYD-SP28_assoc PF14775.1 KEP62551.1 - 0.31 10.7 1.9 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain RRM_1 PF00076.17 KEP62552.1 - 4e-18 64.7 0.0 6.7e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62552.1 - 8.6e-13 48.0 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62552.1 - 4.6e-09 35.9 0.0 8.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 KEP62553.1 - 2.7 7.7 17.7 2.9 7.6 12.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3513 PF12026.3 KEP62553.1 - 8.2 5.9 13.0 9.8 5.6 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Vfa1 PF08432.5 KEP62553.1 - 9.2 6.2 25.9 12 5.8 18.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CS PF04969.11 KEP62554.1 - 1.2e-07 32.1 0.0 2.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 CS domain PfkB PF00294.19 KEP62555.1 - 3e-42 144.7 6.1 6.2e-26 91.2 0.5 2.4 2 1 0 2 2 2 2 pfkB family carbohydrate kinase HEAT_2 PF13646.1 KEP62556.1 - 2.3e-05 24.5 38.4 0.017 15.4 2.9 8.2 5 2 2 7 7 7 4 HEAT repeats IBN_N PF03810.14 KEP62556.1 - 0.067 13.1 0.2 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain Penicil_amidase PF01804.13 KEP62556.1 - 0.65 8.9 5.3 0.5 9.3 0.2 2.4 2 0 0 2 2 2 0 Penicillin amidase EF-hand_7 PF13499.1 KEP62557.1 - 6.8e-21 74.1 0.1 1.2e-10 41.4 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP62557.1 - 3.1e-20 69.8 0.0 3.4e-06 25.9 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 KEP62557.1 - 5.4e-16 56.9 0.0 3e-05 23.5 0.0 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KEP62557.1 - 8.3e-16 57.3 0.1 6e-09 35.3 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KEP62557.1 - 6.5e-14 50.5 0.0 0.0002 20.5 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 KEP62557.1 - 7.8e-06 25.7 0.2 0.00015 21.5 0.0 2.4 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KEP62557.1 - 2.8e-05 24.1 0.1 0.00024 21.1 0.0 2.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KEP62557.1 - 0.022 14.4 0.0 1.1 8.9 0.0 2.2 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 KEP62557.1 - 0.06 13.0 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TerB EF-hand_10 PF14788.1 KEP62557.1 - 0.063 12.9 0.4 3.4 7.4 0.0 2.8 2 1 1 3 3 3 0 EF hand FANCI_HD2 PF14680.1 KEP62557.1 - 0.065 12.3 0.3 0.092 11.8 0.2 1.4 1 1 0 1 1 1 0 FANCI helical domain 2 DUF1007 PF06226.8 KEP62557.1 - 0.095 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) Ubiquitin_2 PF14560.1 KEP62558.1 - 5.2e-11 42.6 0.0 7.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 KEP62558.1 - 2.8e-10 39.7 0.0 9.2e-10 38.0 0.0 1.8 1 1 0 1 1 1 1 CAP-Gly domain DUF727 PF05303.7 KEP62559.1 - 0.045 13.5 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF727) CGI-121 PF08617.5 KEP62561.1 - 6.2e-21 74.7 0.0 8.5e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bcl-2 PF00452.14 KEP62563.1 - 0.11 12.6 0.0 0.59 10.2 0.0 2.2 3 0 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Ctr PF04145.10 KEP62563.1 - 0.17 11.9 1.9 0.41 10.6 0.0 2.1 1 1 1 2 2 2 0 Ctr copper transporter family Oxysterol_BP PF01237.13 KEP62565.1 - 1.8e-92 309.5 0.7 1.7e-57 194.5 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein DUF1826 PF08856.6 KEP62565.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) EGF_2 PF07974.8 KEP62567.1 - 2e-18 66.2 277.6 1.3e-06 28.4 7.5 15.1 12 2 2 14 14 14 9 EGF-like domain hEGF PF12661.2 KEP62567.1 - 2.2e-08 33.6 128.0 0.00064 19.6 1.7 14.7 15 0 0 15 15 15 8 Human growth factor-like EGF EGF PF00008.22 KEP62567.1 - 4.4e-05 23.3 27.4 0.00021 21.1 8.0 14.8 14 1 1 15 15 15 7 EGF-like domain Laminin_EGF PF00053.19 KEP62567.1 - 0.74 9.7 245.3 0.033 14.1 5.8 14.7 4 2 10 14 14 14 0 Laminin EGF-like (Domains III and V) DEAD PF00270.24 KEP62569.1 - 1.8e-17 63.3 0.0 5.3e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62569.1 - 0.0089 15.8 0.1 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UCH PF00443.24 KEP62570.1 - 3.5e-38 131.2 0.0 4.8e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KEP62570.1 - 1.1e-10 41.5 8.9 2.1e-10 40.5 6.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KEP62570.1 - 4.5e-09 36.1 0.0 8.1e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Aminotran_5 PF00266.14 KEP62572.1 - 6.4e-27 94.2 0.0 6.1e-17 61.4 0.0 3.4 3 0 0 3 3 3 3 Aminotransferase class-V ATP_bind_3 PF01171.15 KEP62572.1 - 8.6e-18 64.4 0.0 1.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 PP-loop family EF-hand_7 PF13499.1 KEP62573.1 - 0.048 13.8 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain pair CLAG PF03805.8 KEP62574.1 - 3.8e-09 34.5 0.1 3.8e-09 34.5 0.0 2.7 3 0 0 3 3 3 2 Cytoadherence-linked asexual protein IBV_3A PF03617.8 KEP62574.1 - 0.18 11.6 0.4 0.38 10.5 0.3 1.5 1 0 0 1 1 1 0 IBV 3A protein PDCD2_C PF04194.8 KEP62576.1 - 8.7e-21 74.2 2.6 2.4e-17 63.0 0.0 3.9 3 1 1 4 4 4 3 Programmed cell death protein 2, C-terminal putative domain Rad50_zn_hook PF04423.9 KEP62576.1 - 0.84 9.1 8.8 2.9 7.4 0.5 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif SDA1 PF05285.7 KEP62577.1 - 2.1e-38 132.3 78.1 2.4e-38 132.2 44.8 3.2 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KEP62577.1 - 0.0022 18.2 4.3 0.26 11.5 1.0 2.8 2 0 0 2 2 2 2 NUC130/3NT domain Nol1_Nop2_Fmu PF01189.12 KEP62578.1 - 2.7e-31 109.0 0.0 6.8e-19 68.3 0.0 4.2 3 1 1 4 4 4 4 NOL1/NOP2/sun family FtsJ PF01728.14 KEP62578.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase PAP1 PF08601.5 KEP62578.1 - 0.63 9.6 12.2 1.2 8.7 8.4 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.4 KEP62578.1 - 0.88 8.3 1.8 1.3 7.7 1.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pol_alpha_B_N PF08418.5 KEP62578.1 - 2.5 7.5 11.3 5 6.5 7.9 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DHC_N1 PF08385.7 KEP62579.1 - 3.5e-152 507.7 0.0 3.5e-152 507.7 0.0 4.3 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.10 KEP62579.1 - 7e-144 480.5 0.0 2.5e-142 475.3 0.0 2.8 2 1 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEP62579.1 - 1.7e-128 428.5 3.0 1.7e-128 428.5 2.1 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEP62579.1 - 2.7e-82 275.7 0.0 8.6e-82 274.1 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KEP62579.1 - 1.4e-43 148.4 0.1 3.4e-43 147.0 0.1 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KEP62579.1 - 4.1e-34 117.8 9.1 8.8e-34 116.7 6.3 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 KEP62579.1 - 2.4e-33 115.2 0.0 3.2e-32 111.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 KEP62579.1 - 3.9e-31 107.6 0.0 8.4e-12 44.9 0.0 7.0 5 2 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 KEP62579.1 - 4.8e-15 55.9 0.4 0.0017 18.5 0.0 5.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 KEP62579.1 - 3.9e-13 49.0 0.0 1e-11 44.4 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KEP62579.1 - 8.1e-12 45.4 2.7 0.0011 19.1 0.0 7.0 6 0 0 6 6 5 2 AAA domain AAA_17 PF13207.1 KEP62579.1 - 2.6e-07 31.4 0.9 3.2 8.6 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.1 KEP62579.1 - 3.8e-06 27.2 0.0 3.4 7.9 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 KEP62579.1 - 6.8e-06 26.0 1.6 0.5 10.2 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.1 KEP62579.1 - 4.2e-05 23.2 6.0 0.62 9.8 0.0 5.7 6 0 0 6 6 5 2 Part of AAA domain AAA_14 PF13173.1 KEP62579.1 - 5.9e-05 22.9 0.0 0.53 10.1 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 KEP62579.1 - 7e-05 22.3 0.1 0.03 13.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KEP62579.1 - 0.0023 17.4 0.0 7.5 6.1 0.0 3.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain ResIII PF04851.10 KEP62579.1 - 0.0061 16.4 0.0 1.6 8.5 0.0 3.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 KEP62579.1 - 0.018 15.2 0.1 1.1e+02 3.0 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Mg_chelatase PF01078.16 KEP62579.1 - 0.025 13.7 6.3 6 5.9 0.0 4.6 4 1 1 5 5 5 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 KEP62579.1 - 0.032 13.6 0.1 0.45 9.9 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Atg14 PF10186.4 KEP62579.1 - 9.6 5.0 18.9 6.8 5.5 5.9 3.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 KEP62580.1 - 6.1e-13 48.5 0.0 8.7e-10 38.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KEP62580.1 - 1.3e-10 40.7 0.0 2.8e-10 39.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Rhodanese PF00581.15 KEP62581.1 - 3e-12 46.8 0.0 1.1e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain CorA PF01544.13 KEP62581.1 - 0.13 11.2 2.8 0.21 10.5 2.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FUSC PF04632.7 KEP62581.1 - 4.5 5.5 6.8 11 4.3 4.7 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 KEP62581.1 - 4.8 4.9 12.3 7.9 4.1 8.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KEP62581.1 - 7.6 4.8 9.2 14 3.9 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EB1 PF03271.12 KEP62583.1 - 7.1e-06 25.9 0.8 1.6e-05 24.8 0.5 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif Retinal PF15449.1 KEP62583.1 - 0.056 11.1 5.9 0.064 10.9 4.1 1.1 1 0 0 1 1 1 0 Retinal protein PROL5-SMR PF15621.1 KEP62583.1 - 0.29 11.5 2.9 0.5 10.8 2.0 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family SET PF00856.23 KEP62585.1 - 6.7e-06 26.5 4.5 1.1e-05 25.7 0.0 3.6 3 2 0 3 3 3 1 SET domain eIF-3c_N PF05470.7 KEP62586.1 - 1.3e-123 413.2 25.9 5.6e-123 411.1 18.0 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KEP62586.1 - 3.8e-14 52.8 0.9 1.3e-12 47.9 0.1 3.0 2 0 0 2 2 2 1 PCI domain Apc3 PF12895.2 KEP62586.1 - 0.047 13.8 1.0 0.24 11.5 0.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KEP62586.1 - 0.15 12.0 1.5 0.61 10.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Astro_capsid PF03115.9 KEP62586.1 - 2.2 6.4 9.2 3.4 5.8 6.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF830 PF05708.7 KEP62587.1 - 8.7e-14 51.8 0.0 1.4e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Orthopoxvirus protein of unknown function (DUF830) PH PF00169.24 KEP62587.1 - 4.1e-08 33.3 0.0 8.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEP62587.1 - 2.5e-07 30.9 0.1 7.5e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KEP62587.1 - 0.0064 16.3 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 KEP62587.1 - 0.031 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Ribonuc_red_lgC PF02867.10 KEP62588.1 - 5.9e-212 704.9 0.0 7.6e-212 704.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KEP62588.1 - 4.5e-24 84.0 0.6 1.4e-23 82.4 0.0 2.2 3 0 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KEP62588.1 - 6.8e-11 42.4 0.0 2.1e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain DUF2267 PF10025.4 KEP62588.1 - 0.14 12.1 0.0 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) RRM_1 PF00076.17 KEP62592.1 - 2.9e-19 68.4 0.1 7.9e-17 60.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62592.1 - 1.1e-14 54.1 0.0 2.8e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 KEP62592.1 - 8.6e-14 51.5 0.7 1.8e-13 50.5 0.5 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_5 PF13893.1 KEP62592.1 - 3.1e-10 39.7 0.0 6.7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rhomboid PF01694.17 KEP62593.1 - 1.6e-24 86.5 16.2 3e-24 85.7 11.2 1.4 1 0 0 1 1 1 1 Rhomboid family MobB PF03205.9 KEP62594.1 - 0.00024 20.8 0.0 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KEP62594.1 - 0.0011 19.8 0.0 0.0028 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Clp1 PF06807.9 KEP62594.1 - 0.0055 16.5 0.0 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.12 KEP62594.1 - 0.091 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 KEP62594.1 - 0.41 9.7 0.2 2.1 7.4 0.1 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RRM_1 PF00076.17 KEP62595.1 - 2.8e-21 74.8 0.1 4.8e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62595.1 - 1.4e-14 53.8 0.0 7.6e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62595.1 - 5.6e-05 22.9 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEP62595.1 - 0.011 15.5 0.1 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-RING_2 PF13639.1 KEP62596.1 - 6.1e-08 32.3 4.3 3e-07 30.1 1.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEP62596.1 - 3e-07 29.9 3.4 3e-07 29.9 2.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP62596.1 - 7.5e-07 28.7 1.9 7.5e-07 28.7 1.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP62596.1 - 4.7e-06 26.5 2.9 4.7e-06 26.5 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP62596.1 - 0.00018 21.0 3.2 0.00018 21.0 2.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP62596.1 - 0.00043 20.3 1.2 0.0021 18.0 0.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 KEP62596.1 - 0.002 17.6 1.8 0.0049 16.4 1.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KEP62596.1 - 0.017 14.8 2.6 0.021 14.5 0.9 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 KEP62596.1 - 0.052 13.0 1.2 0.12 11.8 0.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 KEP62596.1 - 0.74 9.7 4.6 2.1 8.3 3.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sec16_C PF12931.2 KEP62597.1 - 2e-16 60.5 0.0 6.5e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Sec23-binding domain of Sec16 Arm PF00514.18 KEP62600.1 - 3.8e-11 42.3 7.7 0.0021 17.8 0.0 6.0 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEP62600.1 - 6.8e-09 35.8 2.5 1.5e-05 25.2 0.0 3.8 2 2 1 3 3 3 2 HEAT repeats V-ATPase_H_C PF11698.3 KEP62600.1 - 0.00029 20.7 0.0 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_EZ PF13513.1 KEP62600.1 - 0.0061 17.0 0.4 0.12 12.8 0.0 3.4 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 KEP62600.1 - 0.011 15.7 6.4 22 5.4 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat DUF1631 PF07793.6 KEP62600.1 - 0.71 7.9 5.0 1.1 7.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) THOC7 PF05615.8 KEP62601.1 - 6.8e-09 36.1 5.4 6.8e-09 36.1 3.7 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 NolV PF06635.7 KEP62601.1 - 3.5 6.7 8.5 1.5 7.8 4.2 1.6 2 0 0 2 2 2 0 Nodulation protein NolV zf-CCCH PF00642.19 KEP62602.1 - 5.5e-08 32.3 9.4 0.00046 19.8 0.7 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEP62602.1 - 0.9 9.6 6.2 2.1 8.5 0.3 3.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Tweety PF04906.8 KEP62603.1 - 0.065 11.6 0.4 0.095 11.0 0.3 1.2 1 0 0 1 1 1 0 Tweety DUF2201_N PF13203.1 KEP62603.1 - 0.74 8.9 12.5 1.1 8.3 8.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Peptidase_S64 PF08192.6 KEP62603.1 - 1.7 6.8 6.3 2.1 6.5 4.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 SDA1 PF05285.7 KEP62603.1 - 2.3 7.4 19.2 3.3 6.8 13.3 1.3 1 1 0 1 1 1 0 SDA1 Macoilin PF09726.4 KEP62603.1 - 3.9 5.6 8.9 4.9 5.3 6.2 1.1 1 0 0 1 1 1 0 Transmembrane protein GTP_EFTU PF00009.22 KEP62604.1 - 2.3e-56 190.1 0.0 3.9e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEP62604.1 - 5.1e-36 122.8 0.4 2.8e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEP62604.1 - 9e-15 54.5 0.4 3e-14 52.8 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEP62604.1 - 0.00017 21.4 0.0 0.00057 19.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KEP62604.1 - 0.00096 18.7 0.2 0.0033 17.0 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 FlpD PF02662.11 KEP62604.1 - 0.021 14.5 0.1 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.13 KEP62604.1 - 0.075 12.8 0.3 0.26 11.1 0.1 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Mito_morph_reg PF14972.1 KEP62605.1 - 0.1 12.0 0.4 0.15 11.4 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator RRM_6 PF14259.1 KEP62606.1 - 6.2e-12 45.3 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP62606.1 - 2.6e-07 30.1 0.0 4.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ketoacyl-synt PF00109.21 KEP62607.1 - 5e-176 583.1 1.0 3e-87 292.2 0.2 2.9 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEP62607.1 - 1.7e-147 487.2 0.1 5e-55 185.9 0.0 4.1 3 1 1 4 4 4 3 KR domain adh_short PF00106.20 KEP62607.1 - 1.8e-121 402.1 1.1 6.2e-48 162.8 0.0 4.6 3 1 1 4 4 4 3 short chain dehydrogenase PS-DH PF14765.1 KEP62607.1 - 3e-103 345.0 8.2 3e-54 184.1 0.5 3.5 3 0 0 3 3 3 3 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KEP62607.1 - 1.1e-101 340.3 1.0 1.6e-58 198.5 0.1 2.7 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KEP62607.1 - 2.2e-83 275.9 0.4 7.4e-41 138.7 0.1 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain AMP-binding PF00501.23 KEP62607.1 - 5.4e-74 249.0 0.0 1.1e-73 247.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme ADH_zinc_N PF00107.21 KEP62607.1 - 3.8e-38 129.9 1.7 1.5e-18 66.5 0.0 3.3 3 0 0 3 3 3 2 Zinc-binding dehydrogenase PP-binding PF00550.20 KEP62607.1 - 3.3e-26 91.3 0.2 5.5e-12 45.7 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 KEP62607.1 - 7.7e-18 65.6 0.1 1.7e-08 35.4 0.0 3.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 KEP62607.1 - 8.1e-13 48.0 12.3 5.8e-07 29.2 0.0 4.7 4 1 0 5 5 5 2 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 KEP62607.1 - 1e-06 27.9 1.1 0.00089 18.3 0.1 2.7 2 0 0 2 2 2 2 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 KEP62607.1 - 7.7e-05 21.7 0.0 0.016 14.1 0.0 2.5 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C_2 PF14535.1 KEP62607.1 - 0.00063 19.7 0.0 0.0031 17.5 0.0 2.3 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 KEP62608.1 - 1.3e-08 34.5 0.5 1.8e-07 30.8 0.0 2.1 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEP62608.1 - 0.0063 16.0 0.2 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_32 PF13679.1 KEP62609.1 - 1.2e-13 51.0 0.0 2.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP62609.1 - 2.6e-11 43.3 0.0 4.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP62609.1 - 2.1e-08 34.7 0.1 4.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEP62609.1 - 1.8e-07 30.7 0.0 3.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KEP62609.1 - 2.6e-07 30.9 0.1 7.6e-07 29.4 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP62609.1 - 1.3e-06 28.7 0.0 3.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEP62609.1 - 3.9e-06 26.1 0.0 6.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEP62609.1 - 2.7e-05 24.1 0.2 7.1e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP62609.1 - 6.5e-05 23.3 0.0 0.00027 21.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.10 KEP62609.1 - 0.00033 19.8 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 KEP62609.1 - 0.00054 19.0 0.0 0.00092 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 KEP62609.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase zf-CCCH PF00642.19 KEP62610.1 - 5.8e-12 44.9 13.7 6.2e-07 28.9 0.3 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Lipocalin_2 PF08212.7 KEP62611.1 - 5.8e-18 65.0 0.0 7.7e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 KEP62611.1 - 0.003 17.5 0.0 0.0093 15.9 0.0 1.8 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Actin PF00022.14 KEP62612.1 - 1.3e-48 165.3 0.0 1.6e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Actin DUF972 PF06156.8 KEP62613.1 - 0.16 12.3 1.7 35 4.7 0.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KEP62613.1 - 3.3 7.2 12.6 9.5 5.7 0.7 3.2 3 0 0 3 3 3 0 IncA protein Usp PF00582.21 KEP62614.1 - 4.8e-12 46.2 1.3 9.3e-11 42.0 0.3 2.3 2 0 0 2 2 2 2 Universal stress protein family OGG_N PF07934.7 KEP62615.1 - 6.4e-16 58.3 0.0 1.2e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KEP62615.1 - 2.7e-05 24.4 0.1 0.00015 22.0 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Cnd1_N PF12922.2 KEP62615.1 - 0.16 11.5 1.7 5.5 6.5 0.4 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term DUF755 PF05501.6 KEP62615.1 - 0.91 9.5 32.8 0.025 14.6 11.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF2217 PF10265.4 KEP62616.1 - 3.6 6.2 6.2 5 5.7 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) HSP70 PF00012.15 KEP62617.1 - 1.8e-35 121.9 0.6 1.1e-18 66.5 0.0 3.9 3 1 1 4 4 4 3 Hsp70 protein TPR_11 PF13414.1 KEP62617.1 - 6e-13 48.2 7.1 5.2e-06 26.0 1.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEP62617.1 - 0.0015 18.0 5.9 0.031 13.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEP62617.1 - 0.0026 17.5 2.6 0.02 14.7 0.5 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEP62617.1 - 0.0064 16.3 8.8 0.084 12.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEP62617.1 - 0.01 15.6 3.7 0.055 13.3 0.2 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Hen1_L PF12623.2 KEP62617.1 - 0.013 14.2 0.0 0.029 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 TPR_14 PF13428.1 KEP62617.1 - 4 8.3 8.7 1.8 9.4 0.5 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.14 KEP62618.1 - 0.15 12.0 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Biotin/lipoate A/B protein ligase family Ssl1 PF04056.9 KEP62619.1 - 8.9e-49 165.6 0.0 1.3e-35 122.8 0.0 2.2 1 1 1 2 2 2 2 Ssl1-like C1_4 PF07975.7 KEP62619.1 - 2.6e-05 24.1 15.5 2.6e-05 24.1 10.7 3.3 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 KEP62619.1 - 3.1e-05 24.1 0.0 4.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 KEP62619.1 - 0.022 14.0 7.9 0.25 10.5 6.9 1.6 2 0 0 2 2 2 0 Transcription factor Tfb4 zf-HIT PF04438.11 KEP62619.1 - 3.7 7.2 17.3 0.18 11.4 2.8 3.2 2 0 0 2 2 2 0 HIT zinc finger LRR_4 PF12799.2 KEP62620.1 - 2.9e-24 84.2 19.5 4e-09 35.9 0.1 6.0 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP62620.1 - 8.2e-19 67.1 16.1 2.9e-06 26.9 0.7 4.5 2 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.1 KEP62620.1 - 7.2e-11 41.9 4.1 1.7e-07 31.0 0.3 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 KEP62620.1 - 8.7e-11 40.3 13.7 0.56 10.4 0.0 7.9 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.1 KEP62620.1 - 2.4e-09 36.2 19.4 0.11 12.6 0.0 7.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 KEP62620.1 - 2.6e-09 35.7 20.0 0.11 12.8 0.1 8.1 8 0 0 8 8 8 3 Leucine rich repeat LRR_3 PF07725.7 KEP62620.1 - 3.6 7.5 9.1 22 5.0 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat S1FA PF04689.8 KEP62621.1 - 0.044 13.6 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA DUF2680 PF10925.3 KEP62621.1 - 0.048 13.5 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DUF4094 PF13334.1 KEP62621.1 - 3.5 8.0 8.0 0.24 11.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) XkdW PF09636.5 KEP62624.1 - 0.024 14.5 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 XkdW protein Sec1 PF00995.18 KEP62625.1 - 1.6e-61 208.6 0.0 4.2e-45 154.4 0.0 3.8 3 1 0 3 3 3 3 Sec1 family HTH_40 PF14493.1 KEP62625.1 - 0.024 14.8 3.7 5.6 7.2 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain DEAD PF00270.24 KEP62626.1 - 1.9e-37 128.3 0.0 5.1e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62626.1 - 6.4e-21 74.0 0.5 1.2e-20 73.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP62626.1 - 0.017 14.9 0.1 0.15 11.9 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Daxx PF03344.10 KEP62626.1 - 0.025 13.1 25.0 0.038 12.4 17.3 1.2 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 KEP62626.1 - 0.045 12.1 27.4 0.077 11.3 19.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_22 PF13401.1 KEP62626.1 - 0.13 12.3 0.4 0.72 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SDA1 PF05285.7 KEP62626.1 - 0.16 11.2 25.0 0.3 10.3 17.4 1.4 1 0 0 1 1 1 0 SDA1 DUF605 PF04652.11 KEP62626.1 - 0.52 9.6 10.5 0.88 8.9 7.3 1.3 1 0 0 1 1 1 0 Vta1 like BUD22 PF09073.5 KEP62626.1 - 0.86 8.6 26.7 0.042 12.9 14.7 1.5 2 0 0 2 2 2 0 BUD22 Patched PF02460.13 KEP62627.1 - 3.1e-46 157.7 0.0 1.6e-40 138.8 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KEP62627.1 - 6.6e-32 110.0 7.4 1.2e-31 109.1 5.1 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation CIAPIN1 PF05093.8 KEP62628.1 - 0.0022 18.0 1.6 0.0022 18.0 1.1 2.2 2 1 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Polysacc_synt_3 PF13440.1 KEP62629.1 - 0.38 10.1 1.9 0.52 9.7 1.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HEAT_2 PF13646.1 KEP62630.1 - 1.4e-11 44.5 16.8 1.6e-05 25.0 0.0 7.5 3 1 3 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 KEP62630.1 - 3.2e-11 43.3 27.7 7.5e-09 35.8 0.1 9.4 10 1 1 11 11 11 2 HEAT-like repeat HEAT PF02985.17 KEP62630.1 - 4.3e-09 35.6 23.4 0.0012 18.7 0.0 10.1 12 1 0 12 12 12 4 HEAT repeat IBN_N PF03810.14 KEP62630.1 - 0.00021 21.1 0.6 0.0016 18.3 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 KEP62630.1 - 0.0079 15.9 5.3 0.71 9.7 0.0 5.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 KEP62630.1 - 0.0084 16.4 1.1 3.3 8.1 0.1 4.6 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KEP62630.1 - 0.012 14.3 0.3 4.1 6.0 0.0 3.5 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 KEP62630.1 - 0.024 14.4 1.3 50 3.6 0.0 4.9 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 tRNA-synt_2b PF00587.20 KEP62632.1 - 1e-11 44.7 0.0 3.1e-05 23.6 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 KEP62632.1 - 3.6e-08 32.8 0.0 0.054 12.5 0.0 4.2 4 0 0 4 4 4 3 Histidyl-tRNA synthetase RNase_T PF00929.19 KEP62633.1 - 3.3e-07 30.7 0.0 9.3e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Exonuclease OB_NTP_bind PF07717.11 KEP62634.1 - 5.9e-13 48.6 0.1 2e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEP62634.1 - 7e-12 45.0 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 KEP62634.1 - 1.7e-08 34.3 0.4 8.3e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 KEP62634.1 - 1.3e-05 24.7 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEP62634.1 - 0.025 14.7 0.1 0.2 11.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEP62634.1 - 0.035 13.6 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TRAM_LAG1_CLN8 PF03798.11 KEP62635.1 - 1.4e-11 44.3 0.7 1.4e-11 44.3 0.5 2.9 3 0 0 3 3 3 1 TLC domain OST3_OST6 PF04756.8 KEP62636.1 - 3.8e-11 42.8 0.4 7.6e-11 41.8 0.3 1.4 1 0 0 1 1 1 1 OST3 / OST6 family PI3_PI4_kinase PF00454.22 KEP62639.1 - 1.5e-30 106.4 0.1 9.2e-29 100.5 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KEP62639.1 - 1.4e-07 30.9 0.9 2.4e-07 30.0 0.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UQ_con PF00179.21 KEP62643.1 - 5.6e-28 97.1 0.1 9.4e-28 96.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEP62643.1 - 1.4e-07 31.3 0.0 2.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KEP62643.1 - 0.00012 21.7 0.1 0.00019 21.0 0.1 1.3 1 0 0 1 1 1 1 UEV domain SAG PF04092.8 KEP62647.1 - 8.8e-16 58.4 17.8 1.4e-07 31.9 5.7 2.4 2 0 0 2 2 2 2 SRS domain Nup84_Nup100 PF04121.8 KEP62648.1 - 6.5e-08 30.7 0.0 0.0037 15.0 0.0 2.1 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 Myb_Cef PF11831.3 KEP62650.1 - 2.9e-36 124.8 7.2 2.9e-36 124.8 5.0 3.8 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KEP62650.1 - 7e-20 70.8 5.6 2e-10 40.5 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEP62650.1 - 1.3e-16 60.4 6.1 4.7e-12 45.8 1.3 3.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain 2_5_RNA_ligase2 PF13563.1 KEP62653.1 - 0.0075 15.9 0.1 0.67 9.6 0.0 2.5 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily GRA6 PF05084.8 KEP62654.1 - 1.6e-86 289.3 11.0 1.9e-86 289.0 7.6 1.0 1 0 0 1 1 1 1 Granule antigen protein (GRA6) RskA PF10099.4 KEP62654.1 - 0.0086 15.8 0.2 0.69 9.6 0.0 2.2 2 0 0 2 2 2 2 Anti-sigma-K factor rskA DUF3357 PF11837.3 KEP62654.1 - 0.014 15.2 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2142 PF09913.4 KEP62654.1 - 0.014 14.1 0.1 0.024 13.3 0.0 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) DUF2077 PF09850.4 KEP62654.1 - 0.047 13.0 0.5 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF4613 PF15390.1 KEP62655.1 - 1.5 6.8 1.5 4.1 5.4 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) V_ATPase_I PF01496.14 KEP62655.1 - 1.6 6.5 4.6 3.1 5.5 3.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Amino_oxidase PF01593.19 KEP62656.1 - 8.5e-73 245.9 3.7 3.7e-29 102.0 0.0 4.8 4 1 0 4 4 4 4 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEP62656.1 - 1.1e-09 38.1 2.1 5.3e-09 35.9 0.3 3.0 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain zf-HC5HC2H PF13771.1 KEP62656.1 - 3e-09 36.9 1.0 8e-09 35.5 0.7 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain Pyr_redox_3 PF13738.1 KEP62656.1 - 1.3e-05 25.3 0.1 4.4e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEP62656.1 - 1.7e-05 24.7 0.3 3.2e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEP62656.1 - 0.00045 19.1 1.1 0.00066 18.6 0.8 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A zf-HC5HC2H_2 PF13832.1 KEP62656.1 - 0.0012 18.8 1.3 0.0028 17.6 0.9 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain Pyr_redox PF00070.22 KEP62656.1 - 0.017 15.4 0.5 0.081 13.3 0.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 KEP62656.1 - 0.028 13.7 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 KEP62656.1 - 0.045 13.8 0.2 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 KEP62656.1 - 0.045 12.8 0.6 0.076 12.0 0.4 1.2 1 0 0 1 1 1 0 Thi4 family CPSase_L_chain PF00289.17 KEP62656.1 - 0.045 13.8 0.3 0.088 12.9 0.2 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HI0933_like PF03486.9 KEP62656.1 - 0.073 11.5 1.0 0.12 10.8 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 KEP62656.1 - 0.21 11.1 0.1 0.43 10.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 KEP62656.1 - 3.3 7.5 3.3 1.1 9.0 0.1 1.7 2 0 0 2 2 2 0 ThiF family DUF1394 PF07159.7 KEP62656.1 - 6.8 5.7 0.0 11 5.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) PC_rep PF01851.17 KEP62658.1 - 1.5e-05 24.9 8.9 0.36 11.1 0.0 4.9 5 0 0 5 5 5 3 Proteasome/cyclosome repeat SAG PF04092.8 KEP62660.1 - 3.6e-16 59.6 18.3 8.9e-10 39.0 3.4 2.4 2 0 0 2 2 2 2 SRS domain RabGAP-TBC PF00566.13 KEP62661.1 - 1.6e-33 115.9 0.6 1.1e-17 64.2 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ribosomal_L29 PF00831.18 KEP62662.1 - 3.7e-06 26.5 0.9 9.4e-06 25.2 0.6 1.8 1 0 0 1 1 1 1 Ribosomal L29 protein Penicil_amidase PF01804.13 KEP62663.1 - 1e-87 295.9 0.0 2.4e-56 192.2 0.0 2.9 2 1 0 2 2 2 2 Penicillin amidase zf-C2H2_jaz PF12171.3 KEP62664.1 - 0.00038 20.4 0.2 0.00065 19.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEP62664.1 - 0.00074 19.6 0.2 0.0013 18.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 KEP62664.1 - 0.017 14.6 0.2 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 U1 zinc finger Kinase-like PF14531.1 KEP62665.1 - 2.6e-24 85.7 0.1 3.1e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Kinase-like Kinase-like PF14531.1 KEP62666.1 - 1.9e-105 352.0 0.0 2.3e-105 351.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP62666.1 - 0.0018 17.4 0.0 0.0032 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KEP62666.1 - 0.041 12.9 0.1 0.068 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KEP62666.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase dCMP_cyt_deam_1 PF00383.17 KEP62667.1 - 2.2e-06 27.2 0.1 2.2e-06 27.2 0.1 2.3 3 1 0 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region Rota_NSP3 PF01665.11 KEP62667.1 - 0.13 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 WD40 PF00400.27 KEP62669.1 - 7.1e-94 304.6 17.7 1.4e-13 50.1 0.0 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 KEP62669.1 - 1.6e-11 44.0 1.1 2.4e-11 43.4 0.8 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KEP62669.1 - 8.4e-06 24.1 9.2 0.098 10.7 0.0 4.6 1 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KEP62669.1 - 3.1e-05 23.7 0.0 0.33 10.6 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KEP62669.1 - 3.2e-05 22.8 0.2 0.034 12.9 0.0 2.8 2 2 0 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 KEP62669.1 - 0.0009 17.6 0.1 0.17 10.1 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 KEP62669.1 - 0.0034 16.9 0.9 3.5 7.3 0.0 3.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat YEATS PF03366.11 KEP62670.1 - 1.3e-27 95.2 0.0 2.3e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 YEATS family AAA_16 PF13191.1 KEP62671.1 - 0.0054 16.7 0.2 0.021 14.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEP62671.1 - 0.054 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEP62671.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UPF0150 PF03681.10 KEP62671.1 - 0.36 10.4 2.1 0.73 9.5 1.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) PI3_PI4_kinase PF00454.22 KEP62672.1 - 4.6e-35 121.1 0.0 3.9e-34 118.1 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KEP62672.1 - 8.8e-17 60.8 0.0 9.5e-12 44.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 KEP62672.1 - 0.00012 21.8 0.0 0.00052 19.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Glyco_transf_15 PF01793.11 KEP62673.1 - 0.71 8.7 0.0 1.4 7.7 0.0 1.4 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Pkinase PF00069.20 KEP62674.1 - 2.5e-52 177.6 0.0 5.2e-36 124.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP62674.1 - 9.2e-22 77.3 0.1 4.9e-15 55.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KEP62674.1 - 0.00024 20.2 0.4 0.00047 19.2 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEP62674.1 - 0.00042 19.3 0.1 0.034 13.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEP62674.1 - 0.03 14.0 6.3 0.04 13.6 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEP62674.1 - 0.19 10.5 0.0 0.37 9.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 zf-C3HC4_3 PF13920.1 KEP62676.1 - 1.3e-08 34.3 5.4 2.9e-08 33.2 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP62676.1 - 1.4e-07 31.4 9.8 3.7e-07 30.0 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP62676.1 - 1.8e-07 30.7 7.2 4.5e-07 29.4 5.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP62676.1 - 2.2e-07 30.6 10.7 2.2e-07 30.6 7.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KEP62676.1 - 1.7e-06 27.6 5.9 3.8e-06 26.5 4.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEP62676.1 - 3e-05 23.6 6.6 7.3e-05 22.4 4.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 KEP62676.1 - 5e-05 23.1 0.1 0.00022 21.0 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-C3HC4_4 PF15227.1 KEP62676.1 - 0.00042 20.1 10.7 0.0011 18.8 7.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Peptidase_C97 PF05903.9 KEP62676.1 - 0.038 13.7 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain zf-rbx1 PF12678.2 KEP62676.1 - 0.1 12.6 2.8 0.32 11.1 1.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 KEP62676.1 - 0.14 11.7 3.8 0.32 10.5 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4468 PF14730.1 KEP62678.1 - 0.041 13.5 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold PagP PF07017.6 KEP62678.1 - 0.2 10.9 2.1 0.25 10.6 1.5 1.1 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP FAD_binding_2 PF00890.19 KEP62680.1 - 1.5e-120 402.8 6.0 1.5e-120 402.8 4.2 1.7 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.15 KEP62680.1 - 2e-45 153.7 2.4 3.2e-45 153.1 1.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 KEP62680.1 - 6.3e-06 25.4 0.5 0.0031 16.6 0.1 2.7 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KEP62680.1 - 1.1e-05 24.4 0.7 0.00016 20.7 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEP62680.1 - 1.7e-05 24.7 0.2 0.0036 17.2 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEP62680.1 - 0.00051 19.0 3.7 0.0091 14.8 1.4 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KEP62680.1 - 0.0017 17.4 0.3 0.0033 16.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEP62680.1 - 0.22 9.9 1.7 0.33 9.3 0.5 1.8 2 0 0 2 2 2 0 HI0933-like protein Epimerase_Csub PF13950.1 KEP62680.1 - 2.2 8.2 5.0 9 6.3 0.2 3.1 3 0 0 3 3 3 0 UDP-glucose 4-epimerase C-term subunit AP2 PF00847.15 KEP62681.1 - 8.2e-22 77.1 7.4 4.4e-11 42.7 0.6 2.7 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.1 KEP62681.1 - 1.6e-16 60.2 0.1 2.8e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal PRMT5 PF05185.11 KEP62682.1 - 1.5e-118 396.5 0.0 4.3e-106 355.5 0.0 3.2 2 1 0 2 2 2 2 PRMT5 arginine-N-methyltransferase Exo5 PF09810.4 KEP62683.1 - 2.4e-08 33.5 0.1 5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Exo5 PF09810.4 KEP62684.1 - 2.4e-44 151.8 0.0 6.9e-44 150.3 0.0 1.7 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease ATP-synt_DE PF00401.15 KEP62686.1 - 4.5 7.2 11.8 0.62 9.9 2.4 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Methyltransf_5 PF01795.14 KEP62688.1 - 1.4e-69 234.7 0.1 7.9e-33 114.0 0.0 4.2 4 0 0 4 4 4 4 MraW methylase family Methyltransf_31 PF13847.1 KEP62688.1 - 3.9e-05 23.2 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KEP62688.1 - 0.00011 22.1 0.0 0.095 12.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KEP62688.1 - 0.00057 20.4 0.1 0.91 10.1 0.1 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KEP62688.1 - 0.0028 17.3 0.0 0.0074 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP62688.1 - 0.0044 17.4 0.2 1.5 9.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEP62688.1 - 0.011 15.1 0.1 0.63 9.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KEP62688.1 - 0.012 16.0 0.0 14 6.2 0.0 3.7 4 1 0 4 4 4 0 Methyltransferase domain PCMT PF01135.14 KEP62688.1 - 0.027 13.9 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HHH_3 PF12836.2 KEP62688.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif TPR_11 PF13414.1 KEP62689.1 - 3e-08 33.1 1.8 1.1e-06 28.1 0.3 2.7 2 0 0 2 2 2 1 TPR repeat DUF4511 PF14974.1 KEP62689.1 - 0.0022 17.7 0.0 0.031 14.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4511) TPR_2 PF07719.12 KEP62689.1 - 0.0087 15.9 1.7 0.77 9.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62689.1 - 0.0093 16.6 5.2 0.034 14.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEP62689.1 - 0.011 15.2 3.8 0.19 11.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 KEP62690.1 - 1.9e-14 53.1 22.7 3e-14 52.5 15.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily A_deaminase PF00962.17 KEP62691.1 - 2.6e-50 171.2 0.1 1.4e-43 149.1 0.1 3.0 3 0 0 3 3 3 3 Adenosine/AMP deaminase DUF1512 PF07431.7 KEP62691.1 - 0.13 10.9 0.0 0.28 9.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) Ribosomal_L1 PF00687.16 KEP62692.1 - 4.7e-48 163.4 2.4 5.6e-48 163.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TetR PF13972.1 KEP62692.1 - 0.097 12.1 0.2 0.2 11.0 0.1 1.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor Ribosomal_S24e PF01282.14 KEP62693.1 - 5.5e-26 90.1 0.0 8.4e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e MIP PF00230.15 KEP62694.1 - 4.4e-21 75.3 16.1 7.3e-21 74.6 11.2 1.3 1 1 0 1 1 1 1 Major intrinsic protein EpuA PF11772.3 KEP62694.1 - 0.091 12.2 9.8 0.13 11.6 0.6 3.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta WWE PF02825.15 KEP62695.1 - 1.9e-16 59.2 4.8 5.6e-12 44.9 0.8 2.9 2 1 0 2 2 2 2 WWE domain zf-RING_2 PF13639.1 KEP62695.1 - 1.1e-08 34.7 2.6 2e-07 30.6 1.8 2.5 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP62695.1 - 8.3e-07 29.0 0.0 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP62695.1 - 1.8e-05 24.2 0.3 4.6e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KEP62695.1 - 0.0061 16.2 0.1 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 PHD-finger zf-Nse PF11789.3 KEP62695.1 - 0.012 15.1 0.0 0.039 13.4 0.0 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 KEP62695.1 - 0.013 15.2 0.6 0.032 13.9 0.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP62695.1 - 0.013 15.4 0.4 0.013 15.4 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) V-ATPase_H_N PF03224.9 KEP62696.1 - 0.019 14.0 0.4 0.023 13.8 0.3 1.1 1 0 0 1 1 1 0 V-ATPase subunit H DUF4168 PF13767.1 KEP62696.1 - 0.08 13.5 1.3 0.91 10.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Synaptobrevin PF00957.16 KEP62697.1 - 4.4e-17 61.4 1.4 6.8e-17 60.8 1.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEP62697.1 - 7.6e-07 28.6 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DPCD PF14913.1 KEP62698.1 - 2.1e-55 186.8 0.0 2.6e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family RRM_1 PF00076.17 KEP62699.1 - 3.3e-16 58.6 0.1 6.2e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62699.1 - 1e-15 57.4 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62699.1 - 1.6e-11 43.8 0.1 2.7e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Tim10_DDP PF02953.10 KEP62700.1 - 2.7e-20 71.4 0.1 3e-20 71.2 0.1 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KEP62700.1 - 0.071 12.5 0.1 0.084 12.3 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) MFS_1 PF07690.11 KEP62701.1 - 2.8e-13 49.3 29.3 3.7e-13 48.9 20.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nop14 PF04147.7 KEP62703.1 - 3.3 5.5 12.2 5.3 4.8 8.5 1.2 1 0 0 1 1 1 0 Nop14-like family IncA PF04156.9 KEP62704.1 - 0.11 12.0 4.3 0.11 12.0 1.8 1.9 2 0 0 2 2 2 0 IncA protein Pyr_excise PF03013.9 KEP62707.1 - 0.04 13.6 0.1 0.088 12.5 0.1 1.5 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase AP2 PF00847.15 KEP62707.1 - 0.051 13.7 2.4 0.1 12.7 1.7 1.5 1 0 0 1 1 1 0 AP2 domain AAA_23 PF13476.1 KEP62709.1 - 0.021 15.1 0.6 0.029 14.6 0.4 1.3 1 0 0 1 1 1 0 AAA domain SP2 PF03014.9 KEP62709.1 - 0.027 12.3 0.2 0.039 11.8 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 POTRA_2 PF08479.6 KEP62709.1 - 0.11 12.1 0.1 0.38 10.4 0.0 2.0 1 0 0 1 1 1 0 POTRA domain, ShlB-type V_ATPase_I PF01496.14 KEP62709.1 - 0.21 9.4 0.9 0.29 8.9 0.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HrpB7 PF09486.5 KEP62709.1 - 0.31 10.9 11.8 0.11 12.4 3.8 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2336 PF10098.4 KEP62709.1 - 1 8.5 13.6 0.38 9.9 0.6 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2336) DUF2796 PF10986.3 KEP62710.1 - 0.0079 16.1 0.2 0.0079 16.1 0.2 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2796) Spore_coat_CotO PF14153.1 KEP62710.1 - 4.4 6.6 24.9 0.15 11.4 0.2 2.8 3 0 0 3 3 3 0 Spore coat protein CotO Saccharop_dh PF03435.13 KEP62711.1 - 1.8e-16 60.1 0.1 2.5e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KEP62711.1 - 0.02 14.8 0.1 1 9.3 0.1 2.5 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 KEP62711.1 - 0.068 12.4 0.0 0.19 10.9 0.0 1.7 1 1 0 1 1 1 0 NmrA-like family DUF1604 PF07713.8 KEP62711.1 - 0.079 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Fer2_3 PF13085.1 KEP62712.1 - 3e-32 110.7 0.0 6.5e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KEP62712.1 - 3.1e-10 40.2 4.7 3.1e-10 40.2 3.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KEP62712.1 - 3e-08 33.5 4.6 3e-08 33.5 3.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KEP62712.1 - 2.8e-06 27.6 0.9 2.8e-06 27.6 0.6 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 KEP62712.1 - 0.0029 17.3 0.6 0.0029 17.3 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 KEP62712.1 - 0.0037 17.5 2.4 0.021 15.1 0.6 3.4 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KEP62712.1 - 0.021 14.5 8.2 0.021 14.5 5.7 3.0 2 2 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 KEP62712.1 - 0.034 14.5 7.4 0.034 14.5 5.1 3.1 2 2 1 3 3 3 0 4Fe-4S dicluster domain CPSase_L_D2 PF02786.12 KEP62713.1 - 1.5e-108 360.9 0.3 5.9e-81 270.7 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KEP62713.1 - 5.6e-47 158.5 0.0 1.2e-46 157.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KEP62713.1 - 5.4e-44 149.9 0.0 1.8e-43 148.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 KEP62713.1 - 1.6e-40 137.7 0.0 4.9e-40 136.1 0.0 1.9 2 0 0 2 2 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KEP62713.1 - 6.8e-37 125.9 0.0 2.4e-17 63.0 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KEP62713.1 - 6.9e-34 117.1 1.2 4.4e-19 68.9 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEP62713.1 - 3.5e-26 91.7 0.7 2e-16 59.6 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KEP62713.1 - 2.2e-16 59.7 0.3 2.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KEP62713.1 - 1.8e-12 47.0 0.0 1.2e-10 41.1 0.0 3.2 2 1 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 KEP62713.1 - 2.5e-12 46.6 3.1 2.4e-05 23.8 0.1 3.2 3 2 0 3 3 3 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 KEP62713.1 - 1.4e-07 31.2 0.0 1.9e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 KEP62713.1 - 2.2e-05 24.3 1.4 0.042 13.7 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.14 KEP62713.1 - 0.00018 21.1 0.6 0.026 14.0 0.0 3.0 3 1 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 KEP62713.1 - 0.011 15.7 0.0 8.5 6.4 0.0 3.0 2 0 0 2 2 2 0 TrkA-N domain DJ-1_PfpI PF01965.19 KEP62713.1 - 0.018 14.4 0.0 0.064 12.7 0.0 1.9 1 0 0 1 1 1 0 DJ-1/PfpI family ATP-grasp_5 PF13549.1 KEP62713.1 - 0.036 13.2 0.1 0.13 11.4 0.2 1.7 2 0 0 2 2 2 0 ATP-grasp domain TPK_catalytic PF04263.11 KEP62714.1 - 1.3e-16 60.2 0.0 2.9e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KEP62714.1 - 2.5e-10 39.9 0.0 5.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SPX PF03105.14 KEP62714.1 - 0.0026 17.5 0.0 0.0066 16.2 0.0 1.7 2 1 0 2 2 2 1 SPX domain RRM_1 PF00076.17 KEP62715.1 - 2.5e-16 59.0 0.2 8.2e-09 34.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62715.1 - 2.3e-15 56.3 0.0 2.6e-08 33.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62715.1 - 1.2e-09 37.8 0.1 9.1e-06 25.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4339 PF14237.1 KEP62715.1 - 3e-05 23.5 0.0 6.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) Activator_LAG-3 PF11498.3 KEP62717.1 - 0.15 10.7 1.4 0.42 9.2 0.3 1.9 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Clathrin PF00637.15 KEP62718.1 - 6.8e-08 32.2 7.8 0.0056 16.2 0.0 6.1 3 2 3 6 6 6 2 Region in Clathrin and VPS TPR_2 PF07719.12 KEP62718.1 - 4.1e-06 26.2 23.4 0.045 13.6 0.2 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEP62718.1 - 4.7e-05 22.9 20.0 0.053 13.1 0.2 6.8 6 1 0 6 6 6 2 TPR repeat Nic96 PF04097.9 KEP62718.1 - 0.0017 16.5 4.8 0.59 8.1 0.0 3.1 1 1 1 3 3 3 2 Nup93/Nic96 Apc3 PF12895.2 KEP62718.1 - 0.016 15.3 26.4 0.17 12.0 0.4 6.4 4 1 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEP62718.1 - 0.053 13.4 30.1 0.054 13.4 2.9 6.7 6 1 2 8 8 8 0 Tetratricopeptide repeat DUF4203 PF13886.1 KEP62718.1 - 0.23 10.9 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) MIT PF04212.13 KEP62718.1 - 0.33 10.8 10.4 7.2 6.5 0.4 4.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 KEP62718.1 - 0.78 10.5 22.0 14 6.6 0.4 8.3 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62718.1 - 0.97 10.1 16.3 30 5.4 1.0 6.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 KEP62718.1 - 4.4 6.0 7.8 3.1 6.5 0.2 3.2 3 1 0 3 3 3 0 Coatomer WD associated region TPR_7 PF13176.1 KEP62718.1 - 6.8 6.7 18.5 14 5.7 0.1 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat OpcA_G6PD_assem PF10128.4 KEP62719.1 - 9.1e-05 21.4 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase subunit WD40 PF00400.27 KEP62719.1 - 0.0012 18.6 1.2 0.079 12.8 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat ACT_7 PF13840.1 KEP62719.1 - 0.0068 15.9 0.0 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 ACT domain Nucleoporin_N PF08801.6 KEP62719.1 - 0.092 11.4 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like Metallophos PF00149.23 KEP62720.1 - 5.1e-36 123.9 0.1 7.1e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AP2 PF00847.15 KEP62723.1 - 4.7e-10 39.4 2.6 1.1e-09 38.2 1.8 1.6 1 0 0 1 1 1 1 AP2 domain Clat_adaptor_s PF01217.15 KEP62725.1 - 4.2e-46 156.2 0.6 4.8e-46 156.0 0.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Cas_DxTHG PF09455.5 KEP62725.1 - 0.075 12.1 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family ATP_bind_3 PF01171.15 KEP62726.1 - 3.6e-09 36.3 0.2 0.0027 17.2 0.0 3.3 3 0 0 3 3 3 3 PP-loop family TilS PF09179.6 KEP62727.1 - 0.12 12.4 0.8 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 TilS substrate binding domain ATP_bind_1 PF03029.12 KEP62728.1 - 4.3e-75 252.3 0.1 5.8e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KEP62728.1 - 0.00019 22.2 0.1 0.00058 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEP62728.1 - 0.00032 20.6 0.0 0.0018 18.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KEP62728.1 - 0.00066 19.2 0.0 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 KEP62728.1 - 0.00076 19.3 0.0 0.0026 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEP62728.1 - 0.0032 16.9 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KEP62728.1 - 0.0074 16.5 0.0 0.029 14.6 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEP62728.1 - 0.0081 16.3 1.8 0.67 10.1 0.2 3.3 2 2 1 3 3 3 1 AAA domain AAA_19 PF13245.1 KEP62728.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KEP62728.1 - 0.013 15.0 0.0 0.053 13.0 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KEP62728.1 - 0.013 15.6 0.0 0.056 13.6 0.0 2.1 2 1 1 3 3 2 0 RNA helicase KTI12 PF08433.5 KEP62728.1 - 0.046 12.9 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 KEP62728.1 - 0.048 13.6 0.1 0.44 10.4 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain ADK PF00406.17 KEP62728.1 - 0.055 13.3 0.1 0.49 10.2 0.0 2.4 2 1 0 2 2 2 0 Adenylate kinase MobB PF03205.9 KEP62728.1 - 0.069 12.8 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PFL PF02901.10 KEP62728.1 - 0.073 11.4 0.1 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase ArgK PF03308.11 KEP62728.1 - 0.078 11.7 0.0 0.22 10.2 0.0 1.6 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 KEP62728.1 - 0.11 11.6 0.0 0.26 10.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Otopetrin PF03189.8 KEP62729.1 - 9.1 5.1 0.2 16 4.3 0.1 1.2 1 0 0 1 1 1 0 Otopetrin Fer2 PF00111.22 KEP62730.1 - 3.5e-19 68.3 1.2 6.1e-19 67.5 0.8 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 KEP62730.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Cytochrom_B_C PF00032.12 KEP62731.1 - 4.2e-12 46.1 0.2 4.5e-12 46.0 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Arf PF00025.16 KEP62732.1 - 5.3e-63 211.3 0.0 5.9e-63 211.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEP62732.1 - 5.1e-11 42.1 0.0 6.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KEP62732.1 - 3.5e-10 40.4 0.0 4.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KEP62732.1 - 4.5e-10 38.7 0.2 8.1e-07 28.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KEP62732.1 - 1.5e-08 34.2 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KEP62732.1 - 1.8e-06 27.8 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KEP62732.1 - 2.8e-06 26.6 0.0 3.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEP62732.1 - 4.5e-05 22.9 0.1 0.0011 18.3 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.3 KEP62732.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) PduV-EutP PF10662.4 KEP62732.1 - 0.037 13.5 0.0 0.085 12.3 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KEP62732.1 - 0.091 12.1 0.0 4.4 6.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TIP120 PF08623.5 KEP62733.1 - 2.2e-23 82.6 0.1 1.4e-21 76.8 0.0 3.6 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 KEP62733.1 - 0.0017 18.2 2.8 0.83 9.4 0.0 4.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_N PF14222.1 KEP62733.1 - 0.031 12.9 0.3 0.15 10.6 0.0 2.1 2 0 0 2 2 2 0 Cell morphogenesis N-terminal HEAT_EZ PF13513.1 KEP62733.1 - 0.032 14.7 0.6 0.032 14.7 0.4 12.2 12 2 2 14 14 14 0 HEAT-like repeat HEAT PF02985.17 KEP62733.1 - 0.48 10.6 0.0 0.48 10.6 0.0 9.1 12 0 0 12 12 12 0 HEAT repeat DUF2890 PF11081.3 KEP62733.1 - 1.6 8.7 10.3 0.83 9.6 2.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) Arm PF00514.18 KEP62733.1 - 3.1 7.7 10.6 1.2 9.1 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat OB_NTP_bind PF07717.11 KEP62734.1 - 3.1e-14 52.7 0.0 8.3e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEP62734.1 - 2.9e-06 27.2 0.0 2.9e-06 27.2 0.0 3.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) MADF_DNA_bdg PF10545.4 KEP62734.1 - 0.11 12.6 7.2 2.2 8.5 0.0 2.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PrsW-protease PF13367.1 KEP62736.1 - 1.1e-12 47.5 17.3 4.2e-11 42.3 5.7 4.0 3 1 0 3 3 3 3 Protease prsW family NTP_transf_2 PF01909.18 KEP62737.1 - 0.0012 19.1 0.1 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 KEP62737.1 - 0.022 14.7 0.1 0.069 13.1 0.1 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase TRAP_alpha PF03896.11 KEP62737.1 - 0.69 8.8 3.6 2 7.3 2.5 1.8 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MCM PF00493.18 KEP62739.1 - 8.1e-120 399.5 0.0 3e-109 364.8 0.0 2.1 2 0 0 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 KEP62739.1 - 1.8e-15 57.4 0.0 6.1e-15 55.7 0.0 2.0 1 1 1 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEP62739.1 - 3.5e-08 32.8 0.1 9.8e-06 24.8 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM2_N PF12619.3 KEP62739.1 - 4.4e-05 23.5 16.1 9.4e-05 22.4 11.2 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.9 KEP62739.1 - 0.00017 21.3 0.0 0.00062 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KEP62739.1 - 0.0002 20.8 0.0 0.0015 18.0 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 KEP62739.1 - 0.0014 18.2 0.0 0.0092 15.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KEP62739.1 - 0.016 15.4 0.0 0.049 13.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP62739.1 - 0.14 12.3 1.3 0.44 10.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain Cucumo_coat PF00760.13 KEP62740.1 - 0.42 9.5 0.0 0.74 8.7 0.0 1.3 1 0 0 1 1 1 0 Cucumovirus coat protein P53_TAD PF08563.6 KEP62742.1 - 1.6 7.8 8.2 7.1 5.8 0.5 2.7 2 0 0 2 2 2 0 P53 transactivation motif GWT1 PF06423.7 KEP62744.1 - 2.8e-19 69.5 0.5 2.8e-19 69.5 0.4 2.2 2 0 0 2 2 2 1 GWT1 Ycf4 PF02392.11 KEP62744.1 - 0.54 9.5 2.5 0.41 9.9 0.3 1.8 2 0 0 2 2 2 0 Ycf4 UL2 PF08196.6 KEP62746.1 - 0.49 10.1 0.2 44 3.9 0.0 2.5 2 0 0 2 2 2 0 UL2 protein MSP1_C PF07462.6 KEP62747.1 - 5.4 5.2 3.0 2.9 6.1 0.1 1.9 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_L9_N PF01281.14 KEP62748.1 - 8.2e-13 47.3 0.0 1.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DXPR_C PF13288.1 KEP62749.1 - 2.9e-41 140.2 0.0 5e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_reductoisom PF02670.11 KEP62749.1 - 2.4e-40 138.0 0.0 3.7e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.7 KEP62749.1 - 6.9e-36 122.0 0.0 1.7e-35 120.7 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Cytomega_UL84 PF06284.6 KEP62749.1 - 0.069 11.5 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein NAD_binding_3 PF03447.11 KEP62749.1 - 0.1 12.9 0.1 0.36 11.2 0.0 1.9 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AP2 PF00847.15 KEP62750.1 - 2.8e-28 97.8 13.5 1.2e-09 38.1 0.2 3.9 3 0 0 3 3 3 3 AP2 domain Xpo1 PF08389.7 KEP62752.1 - 9.8e-10 38.5 2.3 1.9e-09 37.5 0.1 2.9 3 0 0 3 3 3 1 Exportin 1-like protein SRC-1 PF08832.5 KEP62752.1 - 0.062 14.0 2.0 0.1 13.3 0.0 2.5 2 0 0 2 2 2 0 Steroid receptor coactivator G-patch PF01585.18 KEP62753.1 - 2.6e-14 52.7 0.8 2.6e-14 52.7 0.5 2.3 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.17 KEP62753.1 - 0.00013 21.4 0.1 0.00026 20.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KEP62753.1 - 0.0011 18.8 0.3 0.0056 16.4 0.2 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 KEP62753.1 - 0.0042 16.8 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRA1 PF03208.14 KEP62754.1 - 3.3e-21 75.2 2.8 4.5e-21 74.7 1.9 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2061 PF09834.4 KEP62754.1 - 3.6 7.8 7.3 1.3 9.2 0.8 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) MAM33 PF02330.11 KEP62756.1 - 2.2e-22 79.8 1.5 2.2e-16 60.2 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein FERM_C PF09380.5 KEP62756.1 - 0.023 14.8 0.0 0.066 13.4 0.0 1.7 1 1 0 1 1 1 0 FERM C-terminal PH-like domain DUF3529 PF12046.3 KEP62756.1 - 0.053 12.5 0.1 0.094 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) NUDIX PF00293.23 KEP62757.1 - 3.7e-20 71.9 0.7 4.6e-20 71.6 0.1 1.4 2 0 0 2 2 2 1 NUDIX domain Phage_min_tail PF05939.8 KEP62757.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage minor tail protein Ras PF00071.17 KEP62758.1 - 5e-67 224.3 0.7 5.8e-67 224.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP62758.1 - 2e-21 76.7 0.0 2.9e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP62758.1 - 8.7e-17 60.9 0.1 1.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEP62758.1 - 5.5e-07 28.9 0.1 8.3e-07 28.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEP62758.1 - 3e-05 23.5 0.2 6.5e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KEP62758.1 - 3.9e-05 22.9 0.0 4.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEP62758.1 - 6.2e-05 22.9 0.1 0.00011 22.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEP62758.1 - 0.0034 16.5 0.0 0.009 15.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEP62758.1 - 0.0035 17.4 0.0 0.0049 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KEP62758.1 - 0.012 15.0 0.1 0.043 13.2 0.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KEP62758.1 - 0.026 14.2 0.1 0.075 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEP62758.1 - 0.037 14.0 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KEP62758.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 KEP62758.1 - 0.11 11.7 0.0 0.47 9.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 KEP62758.1 - 1.2 7.7 4.5 8.7 4.9 0.5 2.7 1 1 1 2 2 2 0 G-protein alpha subunit 2-Hacid_dh_C PF02826.14 KEP62759.1 - 7e-48 162.1 0.0 1.1e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEP62759.1 - 4.6e-05 22.8 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEP62759.1 - 0.0077 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEP62759.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.16 KEP62759.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2OG-FeII_Oxy_3 PF13640.1 KEP62763.1 - 3.1e-18 66.1 0.3 9.4e-18 64.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEP62763.1 - 0.005 16.4 0.7 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TRAPPC-Trs85 PF12739.2 KEP62764.1 - 8.6e-99 330.9 18.6 4.1e-96 322.1 11.8 3.3 2 1 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.1 KEP62764.1 - 0.099 11.7 2.9 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP V-ATPase_H_N PF03224.9 KEP62765.1 - 4.5 6.2 0.2 14 4.6 0.1 1.7 1 1 0 1 1 1 0 V-ATPase subunit H Prp19_bind PF06991.6 KEP62766.1 - 1.3e-71 241.0 34.9 1.3e-71 241.0 24.2 2.5 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain DUF2841 PF11001.3 KEP62766.1 - 1.5 8.6 6.7 0.93 9.3 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2841) TPR_11 PF13414.1 KEP62768.1 - 6.9e-18 64.0 1.9 4.4e-15 55.0 1.6 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEP62768.1 - 2.2e-13 49.0 2.1 0.0002 21.0 0.6 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP62768.1 - 1.8e-12 46.2 0.8 5.7e-05 22.5 0.4 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62768.1 - 2.4e-08 33.1 0.3 0.023 14.4 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP62768.1 - 6.7e-08 32.3 0.6 3.6e-06 26.8 0.9 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62768.1 - 1.9e-05 25.1 0.2 0.00097 19.7 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEP62768.1 - 3.4e-05 23.8 0.1 0.00015 21.8 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEP62768.1 - 0.038 13.7 6.8 0.08 12.7 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 KEP62768.1 - 0.048 13.5 0.2 0.21 11.4 0.1 2.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 KEP62768.1 - 0.057 13.7 0.2 0.29 11.4 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEP62768.1 - 0.06 13.2 1.1 1.5 8.9 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62768.1 - 0.09 13.4 4.1 1.6 9.5 0.0 4.1 3 2 2 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP62768.1 - 0.12 12.9 4.7 25 5.5 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat fn3 PF00041.16 KEP62769.1 - 0.033 14.3 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 Fibronectin type III domain CBM_4_9 PF02018.12 KEP62769.1 - 0.076 13.0 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain Mucin PF01456.12 KEP62770.1 - 0.0034 17.1 13.0 0.0034 17.1 9.0 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF3439 PF11921.3 KEP62770.1 - 0.4 10.4 17.0 0.96 9.2 11.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 KEP62770.1 - 3 5.5 6.4 4 5.0 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CAF-1_p150 PF11600.3 KEP62771.1 - 0.00028 20.3 32.0 0.00028 20.3 22.2 3.5 3 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 KEP62771.1 - 7 5.0 7.3 13 4.1 5.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DnaJ PF00226.26 KEP62776.1 - 2.1e-27 94.6 0.9 3.4e-27 93.9 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain 7tm_6 PF02949.15 KEP62777.1 - 0.0039 16.0 0.7 0.005 15.7 0.5 1.1 1 0 0 1 1 1 1 7tm Odorant receptor Tfb2 PF03849.9 KEP62778.1 - 2.5e-41 141.5 0.0 1.7e-24 86.1 0.0 4.0 4 0 0 4 4 4 3 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KEP62778.1 - 5.6e-07 29.3 0.1 1.3e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 KEP62778.1 - 0.38 10.2 1.2 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 Anti-repressor SinI SNAP PF14938.1 KEP62779.1 - 0.034 13.2 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Ank_2 PF12796.2 KEP62780.1 - 8.2e-29 99.7 3.4 1.4e-16 60.5 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEP62780.1 - 2.7e-27 93.1 5.0 1.4e-09 37.2 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KEP62780.1 - 2e-22 78.7 4.4 1.8e-09 37.5 0.4 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP62780.1 - 1.3e-19 68.2 1.1 1.1e-06 28.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEP62780.1 - 2.7e-15 56.3 2.7 6.3e-09 36.1 0.4 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Peptidase_M16_C PF05193.16 KEP62781.1 - 9.2e-11 41.7 0.0 7.4e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEP62781.1 - 1.9e-06 27.6 0.0 4.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Rep_fac-A_3 PF08661.6 KEP62782.1 - 4.5e-11 42.6 0.0 5.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_C48 PF02902.14 KEP62783.1 - 7.9e-39 133.5 0.8 1.2e-38 132.9 0.6 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CCDC32 PF14989.1 KEP62783.1 - 0.04 13.7 0.2 0.096 12.5 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing 32 ACPS PF01648.15 KEP62784.1 - 3.1e-08 33.4 0.0 2.6e-07 30.4 0.0 2.4 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily FXa_inhibition PF14670.1 KEP62784.1 - 0.14 12.3 1.6 0.5 10.5 1.1 2.0 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site BMF PF15185.1 KEP62786.1 - 0.058 12.6 0.6 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis TAFII55_N PF04658.8 KEP62788.1 - 3.2e-22 78.7 4.5 4e-22 78.4 0.0 2.4 3 0 0 3 3 3 1 TAFII55 protein conserved region DUF1168 PF06658.7 KEP62788.1 - 0.011 15.3 12.3 0.025 14.0 8.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) U79_P34 PF03064.11 KEP62788.1 - 3.6 7.0 14.4 7.7 5.9 10.0 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 BLVR PF06375.6 KEP62788.1 - 5.5 6.8 17.0 0.23 11.2 5.0 2.6 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) zf-CCCH PF00642.19 KEP62792.1 - 5.2e-07 29.1 12.6 0.0016 18.0 1.8 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AhpC-TSA PF00578.16 KEP62793.1 - 2.5e-28 98.2 0.0 3.5e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 KEP62793.1 - 5.6e-16 57.9 0.7 1.2e-15 56.8 0.5 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 KEP62793.1 - 1.3e-10 40.9 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KEP62793.1 - 0.00026 20.9 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme ArfGap PF01412.13 KEP62794.1 - 4.8e-43 145.6 0.2 4.8e-43 145.6 0.1 1.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf NST1 PF13945.1 KEP62794.1 - 0.12 12.4 3.5 0.2 11.7 2.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator CorA PF01544.13 KEP62795.1 - 0.00082 18.4 0.0 0.00082 18.4 0.0 2.0 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF998 PF06197.8 KEP62795.1 - 0.13 11.5 1.5 0.22 10.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Herpes_UL6 PF01763.11 KEP62795.1 - 0.47 8.5 0.8 0.87 7.6 0.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like adh_short PF00106.20 KEP62797.1 - 1.8e-12 47.4 1.9 1.8e-12 47.4 1.3 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEP62797.1 - 0.0092 15.6 0.2 0.023 14.3 0.2 1.8 1 0 0 1 1 1 1 KR domain zf-RING_UBOX PF13445.1 KEP62799.1 - 1.4e-07 31.1 2.8 1.4e-07 31.1 1.9 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KEP62799.1 - 3.1e-07 29.9 3.0 3.1e-07 29.9 2.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP62799.1 - 1.6e-06 28.0 4.8 1.6e-06 28.0 3.3 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEP62799.1 - 1.7e-05 24.6 3.4 1.7e-05 24.6 2.3 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KEP62799.1 - 3.4e-05 23.5 15.0 0.00077 19.2 10.4 2.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEP62799.1 - 0.00016 21.3 4.6 0.00016 21.3 3.2 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEP62799.1 - 0.005 16.4 4.5 0.005 16.4 3.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP62799.1 - 0.074 13.1 5.4 0.17 12.0 0.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger Defensin_beta PF00711.14 KEP62799.1 - 0.72 9.8 5.9 3.4 7.6 2.4 2.7 2 0 0 2 2 2 0 Beta defensin zf-RING_4 PF14570.1 KEP62799.1 - 1.9 8.1 11.4 0.8 9.3 1.4 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HD_3 PF13023.1 KEP62800.1 - 5.3e-42 143.3 0.1 3.7e-41 140.6 0.0 2.0 1 1 0 1 1 1 1 HD domain HD PF01966.17 KEP62800.1 - 1.6e-05 24.9 0.2 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 1 HD domain SAG PF04092.8 KEP62801.1 - 1e-10 42.0 9.2 2e-07 31.4 2.6 2.4 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP62802.1 - 2.9e-21 76.1 16.4 4.3e-11 43.2 4.0 2.2 2 0 0 2 2 2 2 SRS domain s48_45 PF07422.8 KEP62802.1 - 0.0021 18.1 0.5 0.0021 18.1 0.3 2.0 2 0 0 2 2 2 1 Sexual stage antigen s48/45 domain PBP1_TM PF14812.1 KEP62802.1 - 0.016 15.4 0.6 0.046 14.0 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAG PF04092.8 KEP62803.1 - 1.5e-06 28.6 5.5 2.3e-06 28.0 3.8 1.4 1 0 0 1 1 1 1 SRS domain Sushi PF00084.15 KEP62803.1 - 0.0044 17.3 0.2 0.25 11.7 0.0 2.4 2 0 0 2 2 2 1 Sushi domain (SCR repeat) SAG PF04092.8 KEP62804.1 - 1.1e-07 32.2 8.9 2.5e-07 31.1 6.2 1.6 1 1 0 1 1 1 1 SRS domain PAT1 PF09770.4 KEP62804.1 - 0.16 10.2 1.8 0.19 9.9 1.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tox-ART-HYE1 PF15634.1 KEP62804.1 - 0.17 10.8 0.3 0.38 9.6 0.1 1.6 2 0 0 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase AFT PF08731.6 KEP62804.1 - 0.48 10.6 2.3 2.4 8.3 0.0 2.3 2 1 0 2 2 2 0 Transcription factor AFT SAG PF04092.8 KEP62805.1 - 3.2e-08 33.9 3.8 6.4e-08 33.0 2.6 1.5 1 0 0 1 1 1 1 SRS domain MSA-2c PF12238.3 KEP62805.1 - 3.3 7.3 6.1 5.4 6.6 4.2 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c SAG PF04092.8 KEP62806.1 - 3.6e-17 62.9 10.9 2.3e-08 34.4 1.8 2.6 2 1 0 2 2 2 2 SRS domain Adaptin_N PF01602.15 KEP62807.1 - 6.1e-42 143.6 0.0 4.2e-33 114.4 0.0 3.2 3 0 0 3 3 3 3 Adaptin N terminal region Nuf2 PF03800.9 KEP62809.1 - 6.7e-15 55.3 0.0 2.5e-14 53.4 0.0 2.0 1 0 0 1 1 1 1 Nuf2 family Glyco_transf_28 PF03033.15 KEP62809.1 - 0.16 11.6 0.0 0.7 9.6 0.0 2.1 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain IncA PF04156.9 KEP62809.1 - 1.5 8.3 72.1 0.55 9.8 25.9 3.4 1 1 2 3 3 3 0 IncA protein Pox_F11 PF04943.7 KEP62809.1 - 2.8 6.7 7.3 3.6 6.3 4.5 1.6 1 1 0 1 1 1 0 Poxvirus F11 protein DUF2877 PF11392.3 KEP62809.1 - 3.8 7.7 5.2 2.8 8.2 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) DUF4614 PF15391.1 KEP62810.1 - 8.9 6.0 20.6 0.75 9.5 5.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SMC_N PF02463.14 KEP62811.1 - 4.5e-20 71.8 0.0 5.1e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEP62811.1 - 5e-10 40.0 0.0 5e-10 40.0 0.0 5.0 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KEP62811.1 - 0.00059 19.8 0.1 0.0024 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEP62811.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain C2 PF00168.25 KEP62813.1 - 9e-30 102.3 0.0 2.4e-07 30.5 0.0 6.7 6 0 0 6 6 6 6 C2 domain FerI PF08151.7 KEP62813.1 - 0.00031 20.6 0.1 0.003 17.5 0.0 2.5 3 0 0 3 3 3 1 FerI (NUC094) domain Bax1-I PF01027.15 KEP62816.1 - 2.4e-37 128.5 26.4 2.8e-37 128.3 18.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DEAD PF00270.24 KEP62817.1 - 2.2e-37 128.1 0.0 3.9e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP62817.1 - 2.2e-24 85.0 0.8 4.4e-24 84.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.7 KEP62817.1 - 2.2e-09 37.1 0.0 2.4e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 GUCT (NUC152) domain ResIII PF04851.10 KEP62817.1 - 0.0051 16.6 2.5 0.013 15.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Vfa1 PF08432.5 KEP62818.1 - 0.05 13.6 10.4 0.068 13.1 7.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MIP-T3 PF10243.4 KEP62818.1 - 0.31 9.4 16.5 0.32 9.4 11.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Borrelia_P83 PF05262.6 KEP62818.1 - 2.2 6.4 10.2 2.4 6.3 7.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein YqfQ PF14181.1 KEP62818.1 - 4.9 7.1 9.3 11 5.9 6.5 1.7 1 0 0 1 1 1 0 YqfQ-like protein Ycf1 PF05758.7 KEP62818.1 - 5.2 4.6 8.0 5 4.6 5.6 1.0 1 0 0 1 1 1 0 Ycf1 MFS_1 PF07690.11 KEP62819.1 - 2.1e-31 108.9 44.9 1.4e-18 66.7 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3391 PF11871.3 KEP62820.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF872 PF05915.7 KEP62822.1 - 0.17 11.7 1.3 0.27 11.0 0.9 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) TMEM223 PF14640.1 KEP62823.1 - 0.2 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 Pyr_redox_2 PF07992.9 KEP62824.1 - 2.8e-35 122.0 0.7 4.4e-35 121.3 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEP62824.1 - 3.8e-24 84.8 0.0 5.5e-23 81.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEP62824.1 - 1.7e-14 53.9 2.8 8e-12 45.3 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEP62824.1 - 1.8e-07 30.3 0.4 0.00078 18.4 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KEP62824.1 - 5.5e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEP62824.1 - 9.9e-05 21.3 8.9 0.00038 19.4 3.2 2.8 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 KEP62824.1 - 0.00091 19.2 2.8 0.013 15.4 0.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEP62824.1 - 0.0011 17.5 0.6 0.0065 14.9 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KEP62824.1 - 0.0015 17.7 1.8 0.0015 17.7 1.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEP62824.1 - 0.0024 17.0 0.8 0.0047 16.0 0.6 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KEP62824.1 - 0.012 14.4 1.4 0.012 14.4 1.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 KEP62824.1 - 0.017 13.9 2.3 0.036 12.9 1.6 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Ub-Mut7C PF14451.1 KEP62824.1 - 0.049 13.1 0.8 0.41 10.1 0.1 2.3 2 0 0 2 2 2 0 Mut7-C ubiquitin NAD_Gly3P_dh_N PF01210.18 KEP62824.1 - 0.11 12.2 0.2 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Vinculin PF01044.14 KEP62824.1 - 0.14 10.1 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Vinculin family 3HCDH_N PF02737.13 KEP62824.1 - 0.52 9.9 4.7 2.8 7.5 0.4 3.6 5 0 0 5 5 5 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LSM PF01423.17 KEP62825.1 - 3.5e-15 55.2 0.7 4.8e-15 54.8 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEP62825.1 - 7.2e-06 25.8 0.6 1.6e-05 24.6 0.4 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 KEP62825.1 - 0.16 11.8 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain ATP-grasp_2 PF08442.5 KEP62826.1 - 7e-60 201.8 0.0 1.2e-59 201.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KEP62826.1 - 2.7e-20 72.5 0.4 4.7e-20 71.7 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KEP62826.1 - 2.2e-05 23.7 0.1 9.7e-05 21.6 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain OKR_DC_1_N PF03709.10 KEP62826.1 - 0.0089 16.0 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain SDH_alpha PF03313.10 KEP62826.1 - 0.06 12.3 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Serine dehydratase alpha chain Septin PF00735.13 KEP62828.1 - 5.3e-09 35.5 3.6 1.8e-06 27.1 0.0 2.6 3 0 0 3 3 3 2 Septin T2SE PF00437.15 KEP62828.1 - 0.016 14.1 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.15 KEP62828.1 - 0.066 11.8 0.1 0.17 10.4 0.1 1.6 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.1 KEP62828.1 - 0.29 11.0 0.0 0.59 10.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEP62828.1 - 1.8 8.8 6.5 5.6 7.2 2.6 2.2 2 0 0 2 2 2 0 AAA domain Rrp15p PF07890.7 KEP62830.1 - 9.3e-08 32.1 28.8 5e-06 26.6 20.0 2.7 1 1 0 1 1 1 1 Rrp15p EH_Signature PF15611.1 KEP62831.1 - 0.13 11.2 2.2 1.1 8.1 0.1 2.2 1 1 0 2 2 2 0 EH_Signature domain RRM_1 PF00076.17 KEP62832.1 - 2.7e-21 74.9 0.0 7.4e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62832.1 - 3e-19 68.5 0.1 7e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62832.1 - 4.6e-15 55.3 0.0 3e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KEP62832.1 - 0.00017 21.2 0.1 0.58 9.6 0.0 2.5 2 1 0 2 2 2 2 Calcipressin Ribosomal_60s PF00428.14 KEP62833.1 - 3.7e-25 88.1 14.9 4.4e-25 87.9 10.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L5_C PF00673.16 KEP62834.1 - 3.4e-24 84.3 0.0 5.1e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KEP62834.1 - 1.9e-20 72.3 0.2 6.7e-20 70.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 MAP65_ASE1 PF03999.7 KEP62835.1 - 0.91 8.0 4.0 1.2 7.6 2.8 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Abhydrolase_6 PF12697.2 KEP62838.1 - 3e-25 89.4 0.0 5e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP62838.1 - 1.9e-15 56.8 0.0 4e-15 55.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEP62838.1 - 6.3e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KEP62838.1 - 1.8e-07 30.9 0.0 0.009 15.5 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Thioesterase PF00975.15 KEP62838.1 - 0.017 15.3 0.1 0.21 11.7 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.20 KEP62838.1 - 0.11 12.1 0.2 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.7 KEP62838.1 - 0.12 11.1 0.0 3.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Ser_hydrolase PF06821.8 KEP62838.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase PX PF00787.19 KEP62839.1 - 1.1e-20 73.4 0.0 9.9e-20 70.4 0.0 2.4 3 0 0 3 3 3 1 PX domain FlgN PF05130.7 KEP62839.1 - 1.1 9.5 7.0 13 6.0 3.0 2.6 1 1 1 2 2 2 0 FlgN protein Abhydrolase_5 PF12695.2 KEP62842.1 - 3.2e-23 82.0 0.0 1e-22 80.4 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEP62842.1 - 0.0063 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KEP62842.1 - 0.034 13.5 0.2 0.15 11.4 0.1 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.9 KEP62842.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase DUF818 PF05677.7 KEP62842.1 - 0.39 9.3 0.0 0.62 8.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Aa_trans PF01490.13 KEP62843.1 - 8.5e-09 34.3 13.9 3.8e-06 25.6 0.3 3.3 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein Melibiase PF02065.13 KEP62845.1 - 1.5e-16 60.1 0.0 2.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.4 KEP62845.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 PLDc_2 PF13091.1 KEP62846.1 - 1.1e-19 70.4 0.0 8.3e-09 35.2 0.0 4.5 4 1 0 4 4 4 3 PLD-like domain PLDc PF00614.17 KEP62846.1 - 5.4e-11 41.9 0.6 1e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 KEP62846.1 - 0.0011 18.0 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB Abhydrolase_5 PF12695.2 KEP62846.1 - 0.025 14.3 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.27 KEP62847.1 - 1.4e-18 65.9 17.6 2.8e-06 26.9 0.1 7.1 6 1 0 6 6 6 4 WD domain, G-beta repeat NLE PF08154.7 KEP62847.1 - 2.3e-15 56.3 0.0 3.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KEP62847.1 - 0.015 13.4 0.1 0.43 8.6 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEP62847.1 - 0.019 13.6 0.0 0.26 9.9 0.0 2.4 2 1 1 3 3 3 0 Nup133 N terminal like KH_1 PF00013.24 KEP62848.1 - 0.005 16.4 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Dynein_heavy PF03028.10 KEP62849.1 - 3.8e-216 719.4 0.1 1.4e-215 717.5 0.0 2.0 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEP62849.1 - 2.4e-119 398.4 4.5 2.4e-119 398.4 3.1 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 KEP62849.1 - 1.7e-110 370.1 3.9 1.7e-110 370.1 2.7 3.6 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 KEP62849.1 - 1.1e-94 316.2 0.1 1.4e-93 312.6 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEP62849.1 - 1.2e-54 185.1 0.0 2.4e-54 184.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 KEP62849.1 - 1.7e-54 184.7 0.0 3.2e-53 180.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 KEP62849.1 - 1.2e-52 178.0 0.0 2.6e-52 176.9 0.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KEP62849.1 - 6e-49 166.6 8.2 1.2e-48 165.6 5.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEP62849.1 - 4.6e-25 87.9 0.2 7.8e-07 28.9 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEP62849.1 - 2.3e-06 27.7 4.5 0.19 11.8 0.0 6.0 6 0 0 6 6 5 1 AAA domain AAA PF00004.24 KEP62849.1 - 2.8e-06 27.5 2.2 0.2 11.8 0.0 5.8 7 0 0 7 7 5 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEP62849.1 - 0.0015 19.3 1.6 2.3 9.0 0.0 5.1 4 0 0 4 4 4 1 AAA domain PhoH PF02562.11 KEP62849.1 - 0.0051 16.0 0.2 0.076 12.2 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 KEP62849.1 - 0.0089 15.7 2.7 1.4 8.7 0.1 3.3 3 0 0 3 3 2 1 Part of AAA domain DUF258 PF03193.11 KEP62849.1 - 0.014 14.5 0.0 0.14 11.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEP62849.1 - 0.022 15.0 1.0 14 6.0 0.0 4.7 5 0 0 5 5 4 0 AAA domain RNA_helicase PF00910.17 KEP62849.1 - 0.026 14.7 0.0 20 5.4 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_29 PF13555.1 KEP62849.1 - 0.037 13.5 0.3 3.7 7.1 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEP62849.1 - 0.64 10.3 0.0 0.64 10.3 0.0 3.7 4 0 0 4 4 1 0 ABC transporter AAA_10 PF12846.2 KEP62849.1 - 5.8 6.2 8.1 4.6 6.5 0.0 4.5 5 0 0 5 5 5 0 AAA-like domain Lung_7-TM_R PF06814.8 KEP62851.1 - 1.8e-50 171.5 18.6 2.4e-50 171.1 12.9 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 KEP62851.1 - 5.3e-07 29.1 23.8 1.5e-06 27.5 16.5 1.7 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Sushi PF00084.15 KEP62852.1 - 2.1e-07 31.1 0.1 4.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Sushi domain (SCR repeat) CAP_C PF08603.6 KEP62854.1 - 1.9e-53 180.0 4.3 2.5e-53 179.6 3.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KEP62854.1 - 5.2e-07 29.0 4.2 9.6e-07 28.2 2.9 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Crisp PF08562.5 KEP62854.1 - 0.052 13.8 0.6 0.052 13.8 0.4 1.9 2 0 0 2 2 2 0 Crisp Coat_X PF07552.6 KEP62854.1 - 0.74 9.6 5.5 21 5.0 0.0 3.2 2 1 1 3 3 3 0 Spore Coat Protein X and V domain UQ_con PF00179.21 KEP62855.1 - 9.4e-16 57.5 0.0 1.1e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEP62855.1 - 0.057 13.3 0.0 0.058 13.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain RRM_1 PF00076.17 KEP62856.1 - 6e-35 118.7 0.5 2.2e-17 62.4 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP62856.1 - 1.7e-29 101.5 0.2 6.2e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62856.1 - 3.9e-09 36.2 0.2 0.00075 19.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 KEP62856.1 - 0.0031 17.5 0.1 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 Nmi/IFP 35 domain (NID) RNase_T PF00929.19 KEP62858.1 - 1.9e-26 93.2 0.1 2.7e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease TmoB PF06234.7 KEP62858.1 - 0.061 13.1 0.4 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Methyltransf_18 PF12847.2 KEP62859.1 - 7.6e-15 55.4 0.0 1.1e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP62859.1 - 1.2e-14 54.2 0.1 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP62859.1 - 7.4e-13 48.8 0.1 1.2e-12 48.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP62859.1 - 2.5e-10 40.3 0.0 3.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP62859.1 - 1.9e-08 34.6 0.0 2.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP62859.1 - 5.5e-08 33.0 0.2 1.7e-07 31.5 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEP62859.1 - 1.7e-06 27.3 0.0 2.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.6 KEP62859.1 - 4.1e-06 26.3 0.0 1.2e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 KEP62859.1 - 0.00056 19.0 0.0 0.0007 18.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 KEP62859.1 - 0.0013 17.9 0.1 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 KEP62859.1 - 0.003 16.9 0.0 0.005 16.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain ThiF PF00899.16 KEP62859.1 - 0.0062 16.3 0.0 0.013 15.3 0.0 1.5 1 1 0 1 1 1 1 ThiF family Methyltransf_26 PF13659.1 KEP62859.1 - 0.021 14.8 0.0 0.079 12.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 KEP62859.1 - 0.027 14.1 0.3 0.2 11.2 0.2 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_PK PF05891.7 KEP62859.1 - 0.042 13.1 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase N6_N4_Mtase PF01555.13 KEP62859.1 - 0.083 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA methylase AMP-binding PF00501.23 KEP62860.1 - 5.6e-66 222.6 0.0 1.2e-65 221.6 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme DUF2353 PF09789.4 KEP62860.1 - 0.024 13.8 0.6 0.041 13.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Mannosyl_trans PF05007.8 KEP62862.1 - 2e-60 204.6 22.8 1.7e-43 149.1 13.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) DAP3 PF10236.4 KEP62863.1 - 3.1e-27 95.3 0.0 2.6e-13 49.6 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 KEP62863.1 - 0.0047 16.6 0.0 0.54 9.9 0.0 2.9 1 1 0 1 1 1 1 Archaeal ATPase SR-25 PF10500.4 KEP62863.1 - 0.0059 16.1 14.8 0.0059 16.1 10.3 3.6 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Spc97_Spc98 PF04130.8 KEP62864.1 - 6.8e-70 235.9 0.0 2.5e-59 201.0 0.0 3.1 2 1 0 2 2 2 2 Spc97 / Spc98 family Ctr PF04145.10 KEP62865.1 - 0.064 13.3 3.6 0.11 12.6 0.1 3.2 4 0 0 4 4 4 0 Ctr copper transporter family OmpH PF03938.9 KEP62865.1 - 1 9.2 15.1 1.7 8.5 10.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AMP-binding PF00501.23 KEP62866.1 - 2.5e-70 236.9 0.0 4.7e-70 236.0 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Piwi PF02171.12 KEP62867.1 - 2.5e-52 177.7 0.0 4.2e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KEP62867.1 - 2.9e-05 23.3 0.0 5.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Pkinase PF00069.20 KEP62873.1 - 1.2e-09 37.7 0.0 1.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KEP62873.1 - 8.1e-05 22.3 21.2 0.27 11.4 0.4 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KEP62873.1 - 0.0048 17.1 18.4 0.16 12.2 0.0 5.3 6 0 0 6 6 6 2 HEAT repeats WD40 PF00400.27 KEP62873.1 - 0.0091 15.8 0.1 6.4 6.8 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 KEP62873.1 - 0.033 13.2 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase LacY_symp PF01306.14 KEP62875.1 - 0.0079 14.7 1.8 0.0079 14.7 1.3 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter GBP PF02263.14 KEP62877.1 - 9.1e-13 47.8 1.4 2.7e-11 43.0 0.0 3.6 3 1 0 3 3 3 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 KEP62877.1 - 6.9e-07 28.7 4.7 1.4e-06 27.7 3.2 1.4 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain DUF2859 PF11072.3 KEP62877.1 - 0.03 13.7 0.3 1.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) DUF641 PF04859.7 KEP62877.1 - 0.052 13.3 11.6 0.091 12.5 1.9 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Bestrophin PF01062.16 KEP62881.1 - 1.1e-14 54.0 4.9 1.2e-06 27.7 2.3 3.0 3 0 0 3 3 3 3 Bestrophin, RFP-TM, chloride channel DUF1673 PF07895.6 KEP62881.1 - 0.56 9.7 3.6 0.31 10.5 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1673) Mic1 PF07035.7 KEP62883.1 - 0.0013 18.1 0.1 0.0045 16.3 0.1 1.8 1 1 0 1 1 1 1 Colon cancer-associated protein Mic1-like BAG PF02179.11 KEP62884.1 - 0.051 13.7 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 BAG domain CTP_transf_2 PF01467.21 KEP62885.1 - 1.7e-33 115.9 0.0 7.2e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 KEP62885.1 - 0.0005 19.7 0.7 0.77 9.3 0.1 3.0 2 1 0 2 2 2 2 FAD synthetase RCC1_2 PF13540.1 KEP62886.1 - 2.8e-25 87.3 11.6 4.1e-08 32.6 0.3 6.2 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KEP62886.1 - 3.4e-23 81.5 8.9 5.4e-05 23.3 0.2 8.2 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 KEP62888.1 - 6.2e-21 73.4 0.1 3.5e-05 23.4 0.0 7.3 7 1 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KEP62888.1 - 0.02 14.3 0.9 21 4.4 0.0 3.8 3 2 0 4 4 4 0 PQQ-like domain PQQ_3 PF13570.1 KEP62888.1 - 1.3 9.3 5.0 17 5.8 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Dmrt1 PF12374.3 KEP62888.1 - 8 6.8 37.0 8.8 6.7 0.2 4.6 4 0 0 4 4 4 0 Double-sex mab3 related transcription factor 1 Calreticulin PF00262.13 KEP62889.1 - 1.7e-53 181.5 0.0 1.2e-45 155.7 0.0 2.1 1 1 1 2 2 2 2 Calreticulin family PGAP1 PF07819.8 KEP62892.1 - 3.4e-07 30.0 0.0 6.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 KEP62892.1 - 0.0095 15.5 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEP62892.1 - 0.042 13.6 0.2 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family LCAT PF02450.10 KEP62892.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 KEP62892.1 - 0.27 10.4 0.0 2.1 7.5 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Brix PF04427.13 KEP62895.1 - 1.2e-43 149.0 0.0 1.6e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain PAGK PF15284.1 KEP62896.1 - 0.017 14.8 2.2 0.019 14.6 0.0 2.3 2 0 0 2 2 2 0 Phage-encoded virulence factor Glyco_transf_8 PF01501.15 KEP62897.1 - 3e-20 72.6 1.1 7.3e-18 64.8 0.5 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KEP62897.1 - 0.12 11.7 0.1 0.6 9.4 0.1 1.9 2 0 0 2 2 2 0 Mannosyltransferase putative WD40 PF00400.27 KEP62898.1 - 6.4e-30 101.9 15.2 4.7e-05 23.1 0.0 10.3 9 1 0 9 9 9 8 WD domain, G-beta repeat HSP90 PF00183.13 KEP62900.1 - 1.3e-114 383.5 13.4 1.1e-75 255.0 0.7 4.7 4 1 0 4 4 4 3 Hsp90 protein HATPase_c_3 PF13589.1 KEP62900.1 - 1.2e-11 44.4 0.1 2.2e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEP62900.1 - 2e-09 37.1 0.1 5.6e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MIase PF02426.11 KEP62900.1 - 0.035 13.9 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Muconolactone delta-isomerase CwfJ_C_2 PF04676.9 KEP62900.1 - 1.3 9.5 5.6 0.33 11.4 0.1 2.9 4 0 0 4 4 4 0 Protein similar to CwfJ C-terminus 2 MORN PF02493.15 KEP62901.1 - 1.3e-95 307.7 98.9 1.3e-09 37.1 1.0 15.0 15 0 0 15 15 15 14 MORN repeat CENP-F_leu_zip PF10473.4 KEP62902.1 - 0.0051 16.6 10.7 0.0051 16.6 7.4 9.6 3 2 6 9 9 9 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4094 PF13334.1 KEP62902.1 - 0.0066 16.8 1.5 0.0066 16.8 1.0 6.4 6 3 2 8 8 8 2 Domain of unknown function (DUF4094) BRICHOS PF04089.9 KEP62902.1 - 0.91 9.4 6.1 6.6 6.6 0.0 4.7 3 1 1 4 4 4 0 BRICHOS domain DUF948 PF06103.6 KEP62902.1 - 5.1 7.0 41.5 0.045 13.6 0.5 7.5 8 1 1 9 9 9 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 KEP62902.1 - 6.2 5.8 45.7 0.94 8.5 4.0 7.2 4 3 2 8 8 8 0 Reovirus sigma C capsid protein Ras PF00071.17 KEP62903.1 - 2.8e-58 195.8 0.1 3.8e-58 195.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP62903.1 - 1.4e-18 67.4 0.0 2.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP62903.1 - 2.6e-15 56.0 0.1 3.4e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEP62903.1 - 2.1e-06 27.3 0.0 6.5e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEP62903.1 - 7.6e-05 21.9 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEP62903.1 - 0.00037 19.7 0.0 0.00056 19.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEP62903.1 - 0.001 19.0 0.0 0.002 18.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KEP62903.1 - 0.013 15.6 0.0 1.2 9.3 0.0 2.2 1 1 0 2 2 2 0 AAA domain COX2 PF00116.15 KEP62904.1 - 1.1e-37 128.4 0.0 1.4e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain ParcG PF10274.4 KEP62905.1 - 1.7e-71 239.9 0.0 2.1e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Ribosomal_L18e PF00828.14 KEP62906.1 - 2.7e-35 121.5 0.5 3.7e-35 121.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 K167R PF08065.7 KEP62909.1 - 0.0025 17.9 0.1 0.0029 17.6 0.1 1.1 1 0 0 1 1 1 1 K167R (NUC007) repeat DBINO PF13892.1 KEP62909.1 - 0.078 13.0 1.6 0.091 12.7 1.1 1.1 1 0 0 1 1 1 0 DNA-binding domain PDEase_I PF00233.14 KEP62910.1 - 8.8e-42 143.4 0.0 1.3e-41 142.9 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SNF2_N PF00176.18 KEP62912.1 - 5.8e-37 127.0 0.0 8e-30 103.6 0.0 2.8 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP62912.1 - 6.8e-06 25.8 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 KEP62912.1 - 2e-05 24.1 0.4 2e-05 24.1 0.2 2.3 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KEP62912.1 - 0.00047 19.9 4.6 0.00047 19.9 3.2 2.9 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KEP62912.1 - 0.0029 17.2 7.9 0.014 15.1 2.8 3.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEP62912.1 - 0.018 14.6 8.4 0.0071 15.9 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PKD_channel PF08016.7 KEP62913.1 - 2.4e-06 26.2 45.0 6.1e-05 21.6 8.8 4.0 4 0 0 4 4 4 2 Polycystin cation channel PRTase_3 PF15610.1 KEP62913.1 - 0.26 10.1 0.1 0.46 9.3 0.1 1.3 1 0 0 1 1 1 0 PRTase ComF-like RRM_6 PF14259.1 KEP62914.1 - 0.0028 17.5 0.0 0.013 15.4 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP62914.1 - 0.022 14.6 0.0 0.062 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP62914.1 - 0.03 13.9 0.1 0.53 9.9 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 KEP62914.1 - 0.41 8.7 8.9 0.53 8.4 6.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BUD22 PF09073.5 KEP62914.1 - 2.9 6.8 15.3 4.2 6.3 10.6 1.2 1 0 0 1 1 1 0 BUD22 PAN_4 PF14295.1 KEP62915.1 - 5.2e-08 32.4 0.9 5.2e-08 32.4 0.6 2.6 3 0 0 3 3 3 1 PAN domain PAN_1 PF00024.21 KEP62915.1 - 2.6e-05 23.8 0.2 7.1e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 PAN domain Glyco_hydro_16 PF00722.16 KEP62915.1 - 7.2e-05 22.1 0.0 0.00017 20.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HSBP1 PF06825.7 KEP62916.1 - 9.1e-13 47.5 0.5 1.5e-12 46.9 0.4 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 UPF0184 PF03670.8 KEP62916.1 - 0.019 15.1 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Baculo_PEP_C PF04513.7 KEP62916.1 - 0.054 13.3 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_I PF06008.9 KEP62916.1 - 0.056 12.7 0.2 0.081 12.2 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain I Macoilin PF09726.4 KEP62916.1 - 0.97 7.6 3.8 1.2 7.3 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein CAF-1_p150 PF11600.3 KEP62916.1 - 5.2 6.3 5.4 7.6 5.8 3.7 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 KEP62916.1 - 8.2 4.3 7.5 7.7 4.4 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cren7 PF11520.3 KEP62918.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin protein Cren7 CBM_20 PF00686.14 KEP62919.1 - 1.5e-13 50.1 0.0 3.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain DUF773 PF05600.7 KEP62920.1 - 3.1e-37 128.5 7.2 1.2e-24 86.9 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF773) SlyX PF04102.7 KEP62920.1 - 0.023 15.0 9.0 1.5 9.2 1.2 3.9 3 0 0 3 3 3 0 SlyX Transpep_BrtH PF14399.1 KEP62920.1 - 0.05 12.8 0.9 0.072 12.3 0.0 1.6 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase Filament PF00038.16 KEP62920.1 - 0.069 12.6 7.7 3.9 6.8 3.2 2.3 2 0 0 2 2 2 0 Intermediate filament protein CENP-Q PF13094.1 KEP62920.1 - 0.19 11.7 11.0 3.4 7.6 3.9 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.10 KEP62920.1 - 0.25 10.8 8.0 0.12 11.8 1.0 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF641 PF04859.7 KEP62920.1 - 0.32 10.7 6.0 9 6.0 2.1 3.1 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Atg14 PF10186.4 KEP62920.1 - 1.6 7.5 9.3 1.4 7.8 1.9 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sec8_exocyst PF04048.9 KEP62920.1 - 2 8.0 6.3 1.8 8.2 0.9 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Spectrin PF00435.16 KEP62920.1 - 2.6 8.3 11.2 0.22 11.8 1.3 3.3 3 0 0 3 3 3 0 Spectrin repeat SKIP_SNW PF02731.10 KEP62920.1 - 4.8 6.6 9.3 9.2 5.6 3.6 2.4 2 0 0 2 2 2 0 SKIP/SNW domain PNP_UDP_1 PF01048.15 KEP62921.1 - 1.6e-39 135.2 0.1 2e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NIF PF03031.13 KEP62922.1 - 2.6e-45 153.9 0.0 4e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Phosphorylase PF00343.15 KEP62923.1 - 0 1037.4 0.1 0 1037.2 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pox_F11 PF04943.7 KEP62923.1 - 0.021 13.6 0.1 0.052 12.4 0.1 1.6 1 0 0 1 1 1 0 Poxvirus F11 protein Aminotran_1_2 PF00155.16 KEP62924.1 - 4.2e-15 55.5 0.0 5.9e-13 48.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II DUF2076 PF09849.4 KEP62925.1 - 0.0086 16.1 3.0 0.0086 16.1 2.1 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2797 PF10977.3 KEP62925.1 - 0.035 13.7 0.8 0.15 11.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) SlyX PF04102.7 KEP62925.1 - 0.04 14.2 1.1 0.04 14.2 0.8 2.1 2 0 0 2 2 2 0 SlyX Prefoldin PF02996.12 KEP62925.1 - 0.047 13.3 0.3 0.047 13.3 0.2 1.8 2 0 0 2 2 2 0 Prefoldin subunit Flg_hook PF02120.11 KEP62925.1 - 0.052 13.2 1.2 0.084 12.5 0.8 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF4391 PF14335.1 KEP62925.1 - 0.059 12.7 2.1 2.6 7.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) P4Ha_N PF08336.6 KEP62925.1 - 0.15 11.8 1.8 6.6 6.5 0.1 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CCDC155 PF14662.1 KEP62925.1 - 0.37 10.3 5.9 0.13 11.8 0.4 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF1515 PF07439.6 KEP62925.1 - 0.38 10.5 3.6 0.43 10.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) TMF_DNA_bd PF12329.3 KEP62925.1 - 0.38 10.5 7.2 0.49 10.2 0.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 KEP62925.1 - 1.1 9.6 6.9 0.17 12.3 1.0 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Adeno_PIX PF03955.9 KEP62925.1 - 2 8.9 5.3 3.1 8.3 0.5 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Metallophos PF00149.23 KEP62926.1 - 2.4e-45 154.3 0.4 2.9e-45 154.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rsm22 PF09243.5 KEP62927.1 - 1.1e-72 244.3 0.1 2.6e-60 203.8 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 DUF3924 PF13062.1 KEP62927.1 - 0.2 11.5 0.3 0.39 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) Nsp1_C PF05064.8 KEP62929.1 - 0.00011 21.8 2.9 0.00024 20.7 1.1 2.2 2 0 0 2 2 2 1 Nsp1-like C-terminal region ATP-synt_F6 PF05511.6 KEP62929.1 - 0.092 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DUF919 PF06034.6 KEP62929.1 - 3.6 7.2 11.6 11 5.7 3.4 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) IncA PF04156.9 KEP62929.1 - 8.5 5.9 25.2 16 5.0 2.2 2.9 1 1 1 2 2 2 0 IncA protein EMP24_GP25L PF01105.19 KEP62931.1 - 4.5e-24 85.1 0.0 6.1e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Nucleo_P87 PF07267.6 KEP62931.1 - 8.2 4.9 12.4 16 4.0 8.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Phytase-like PF13449.1 KEP62932.1 - 0.0012 18.1 0.2 0.0014 17.9 0.2 1.0 1 0 0 1 1 1 1 Esterase-like activity of phytase PP2C PF00481.16 KEP62933.1 - 2.2e-48 164.8 0.0 1.7e-47 161.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEP62933.1 - 0.00028 20.3 1.0 0.00041 19.8 0.7 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SPX PF03105.14 KEP62934.1 - 1.8e-33 116.5 0.0 3.2e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 SPX domain VTC PF09359.5 KEP62934.1 - 1.5e-15 56.9 0.0 6.4e-15 54.9 0.0 1.9 1 1 0 1 1 1 1 VTC domain DUF202 PF02656.10 KEP62934.1 - 9.3e-12 44.9 2.7 9.3e-12 44.9 1.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF202) FixQ PF05545.6 KEP62934.1 - 0.037 13.6 0.3 0.11 12.1 0.2 1.8 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ GYF PF02213.11 KEP62936.1 - 1.2e-11 44.0 1.3 2.4e-11 43.0 0.9 1.5 1 0 0 1 1 1 1 GYF domain MIP-T3 PF10243.4 KEP62936.1 - 0.21 9.9 42.4 0.72 8.2 29.4 1.9 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Kelch_4 PF13418.1 KEP62937.1 - 5e-46 154.2 10.8 9.2e-10 38.1 0.0 6.8 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KEP62937.1 - 6.4e-46 153.6 12.1 1.2e-11 43.9 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KEP62937.1 - 3.3e-39 132.1 32.0 1.2e-10 41.2 0.1 9.4 10 0 0 10 10 10 6 Galactose oxidase, central domain Kelch_6 PF13964.1 KEP62937.1 - 4.6e-36 121.5 14.3 1.9e-10 40.4 0.0 6.6 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KEP62937.1 - 1.5e-35 119.5 17.5 1.9e-08 33.7 0.0 7.3 7 0 0 7 7 7 6 Kelch motif Kelch_5 PF13854.1 KEP62937.1 - 5.9e-33 112.3 20.1 3.7e-09 36.3 0.1 6.6 6 0 0 6 6 6 6 Kelch motif BTB PF00651.26 KEP62937.1 - 1.8e-19 69.7 0.9 1.5e-18 66.8 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain DUF605 PF04652.11 KEP62938.1 - 0.64 9.3 11.2 0.79 9.0 7.7 1.1 1 0 0 1 1 1 0 Vta1 like AP2 PF00847.15 KEP62941.1 - 8.9e-08 32.1 0.9 1.4e-05 25.1 0.7 2.4 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.1 KEP62941.1 - 0.00085 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal Ded_cyto PF06920.8 KEP62942.1 - 7.9 5.7 24.4 0.89 8.8 0.1 4.8 3 1 1 4 4 4 0 Dedicator of cytokinesis Surfac_D-trimer PF09006.6 KEP62942.1 - 9.5 6.0 8.3 19 5.0 0.1 4.2 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation A2M_N PF01835.14 KEP62943.1 - 0.0093 16.1 0.0 0.075 13.2 0.0 2.6 1 1 0 1 1 1 1 MG2 domain DUF2217 PF10265.4 KEP62943.1 - 1 8.0 2.2 1.8 7.2 1.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Ubiq_cyt_C_chap PF03981.7 KEP62944.1 - 4.3e-05 23.3 0.0 4.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Med21 PF11221.3 KEP62945.1 - 2.6e-06 27.4 1.9 3.4e-06 27.0 1.3 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex FHIPEP PF00771.15 KEP62945.1 - 0.0061 14.9 0.1 0.0077 14.6 0.1 1.1 1 0 0 1 1 1 1 FHIPEP family DUF4589 PF15252.1 KEP62945.1 - 0.043 13.6 0.5 0.052 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) BLOC1_2 PF10046.4 KEP62945.1 - 0.094 12.8 0.6 0.28 11.3 0.1 1.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2514 PF10721.4 KEP62945.1 - 0.51 10.0 6.2 0.29 10.8 3.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF2046 PF09755.4 KEP62945.1 - 0.64 8.8 6.7 5.4 5.8 4.6 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) ERM PF00769.14 KEP62945.1 - 3 7.3 9.2 0.68 9.4 3.6 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Acatn PF13000.2 KEP62946.1 - 7.5e-76 255.7 7.8 5.9e-48 163.7 0.9 3.1 2 1 0 2 2 2 2 Acetyl-coenzyme A transporter 1 HTH_Tnp_Tc5 PF03221.11 KEP62947.1 - 2.1e-07 30.6 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.15 KEP62947.1 - 1.2e-05 25.1 0.1 4.1e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Transposase BrkDBD PF09607.5 KEP62947.1 - 0.00017 21.0 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_29 PF13551.1 KEP62947.1 - 0.002 18.2 0.6 0.0054 16.8 0.4 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 KEP62947.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 KEP62947.1 - 0.083 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Helicase_C_2 PF13307.1 KEP62952.1 - 6e-32 110.8 0.0 3.6e-29 101.8 0.0 2.7 2 1 0 2 2 2 2 Helicase C-terminal domain DEAD_2 PF06733.10 KEP62952.1 - 1.1e-25 90.0 0.0 5.9e-21 74.6 0.0 2.4 2 0 0 2 2 2 2 DEAD_2 ResIII PF04851.10 KEP62952.1 - 2e-05 24.5 0.0 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEP62952.1 - 0.014 14.8 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase SNF2_N PF00176.18 KEP62952.1 - 0.45 9.2 2.0 3.6 6.2 1.4 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain IMCp PF12314.3 KEP62953.1 - 3e-07 30.4 59.1 0.0044 17.1 26.2 3.6 1 1 2 3 3 3 3 Inner membrane complex protein KOW PF00467.24 KEP62954.1 - 0.00052 19.6 0.8 0.00052 19.6 0.5 2.0 2 0 0 2 2 2 1 KOW motif Peptidase_C78 PF07910.8 KEP62955.1 - 1.6e-43 148.3 0.0 2.2e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 VHS PF00790.14 KEP62956.1 - 1.2e-07 31.4 0.3 0.0058 16.2 0.1 2.3 2 0 0 2 2 2 2 VHS domain Ribosomal_S15 PF00312.17 KEP62957.1 - 0.0031 17.2 0.9 0.0072 16.0 0.7 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 Ank_2 PF12796.2 KEP62959.1 - 1.6e-59 198.1 20.6 3.2e-16 59.4 0.1 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP62959.1 - 4.3e-29 100.3 4.8 7.9e-08 32.6 0.0 6.1 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 KEP62959.1 - 1.4e-27 94.0 12.0 0.00023 20.8 0.1 7.5 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KEP62959.1 - 1e-22 77.8 1.9 0.0097 16.0 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEP62959.1 - 3.6e-21 74.7 7.7 3.5e-05 23.8 0.0 5.7 4 1 2 6 6 6 4 Ankyrin repeats (many copies) TPR_11 PF13414.1 KEP62959.1 - 7.6e-16 57.5 10.5 1.9e-11 43.4 2.3 3.4 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KEP62959.1 - 3.7e-11 42.0 9.0 0.0013 18.4 0.3 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP62959.1 - 8.3e-10 37.8 10.3 0.00053 19.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEP62959.1 - 7.8e-06 25.7 8.4 0.0024 17.7 1.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP62959.1 - 3.8e-05 23.5 0.3 0.024 14.8 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62959.1 - 0.0001 21.8 1.1 0.028 14.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62959.1 - 0.0001 22.8 3.2 0.0001 22.8 2.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62959.1 - 0.0013 19.1 1.0 0.0013 19.1 0.7 6.1 6 1 1 7 7 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KEP62959.1 - 0.0083 16.2 3.1 0.7 10.0 0.0 2.9 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KEP62959.1 - 0.014 15.7 1.3 0.014 15.7 0.9 5.0 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEP62959.1 - 0.016 15.0 0.5 0.016 15.0 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP62959.1 - 0.033 13.9 13.7 0.042 13.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEP62959.1 - 0.061 13.4 16.6 2.2 8.4 1.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RR_TM4-6 PF06459.7 KEP62959.1 - 0.37 10.6 4.8 0.62 9.9 3.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TPR_6 PF13174.1 KEP62959.1 - 2.4 8.7 8.4 2.6 8.6 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Neur_chan_memb PF02932.11 KEP62962.1 - 3.4 7.4 3.7 43 3.8 1.9 2.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Shisa PF13908.1 KEP62963.1 - 0.22 11.6 0.1 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1129 PF06570.6 KEP62963.1 - 1.1 8.5 2.3 2.7 7.2 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) UPF0118 PF01594.11 KEP62963.1 - 4.8 6.0 29.9 0.079 11.9 0.9 3.9 4 0 0 4 4 4 0 Domain of unknown function DUF20 SET PF00856.23 KEP62964.1 - 2.3e-09 37.7 0.0 9.9e-09 35.7 0.0 2.2 2 1 0 2 2 2 1 SET domain Lar_restr_allev PF14354.1 KEP62964.1 - 4.6 7.6 10.6 0.098 12.9 0.7 3.2 2 1 1 3 3 3 0 Restriction alleviation protein Lar Effector_1 PF04518.7 KEP62965.1 - 0.01 14.8 1.5 0.01 14.8 1.0 1.6 2 0 0 2 2 2 0 Effector from type III secretion system DUF1192 PF06698.6 KEP62965.1 - 0.011 15.5 2.7 1.7 8.4 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) IncA PF04156.9 KEP62965.1 - 0.015 14.9 8.8 6.7 6.2 7.4 2.7 2 1 0 2 2 2 0 IncA protein Streptin-Immun PF11083.3 KEP62965.1 - 0.077 12.9 3.7 1.5 8.8 0.0 3.1 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein Nucleocap_ssRNA PF11128.3 KEP62965.1 - 0.15 11.5 1.1 0.34 10.3 0.4 1.9 1 1 1 2 2 2 0 Plant viral coat protein nucleocapsid V_ATPase_I PF01496.14 KEP62965.1 - 0.96 7.2 4.7 0.42 8.3 1.0 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GLTSCR1 PF15249.1 KEP62965.1 - 1.2 9.2 4.7 1.9 8.6 0.6 2.9 2 1 1 3 3 3 0 Glioma tumor suppressor candidate region Seryl_tRNA_N PF02403.17 KEP62965.1 - 1.4 9.0 23.3 0.59 10.1 4.5 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 KEP62965.1 - 1.5 8.3 12.4 3.6 7.1 5.4 2.6 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tweety PF04906.8 KEP62965.1 - 1.6 7.0 3.5 0.64 8.3 0.8 1.4 2 0 0 2 2 2 0 Tweety Snapin_Pallidin PF14712.1 KEP62965.1 - 2.6 8.3 10.5 0.59 10.4 3.5 2.3 2 1 0 2 2 2 0 Snapin/Pallidin Prefoldin_2 PF01920.15 KEP62965.1 - 3.8 7.3 18.6 1.5 8.5 2.4 3.3 3 0 0 3 3 3 0 Prefoldin subunit GAS PF13851.1 KEP62965.1 - 5 6.2 15.3 3.2 6.8 6.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CASP_C PF08172.7 KEP62965.1 - 5.8 5.8 15.4 0.97 8.4 1.9 2.7 2 1 0 2 2 2 0 CASP C terminal DUF4140 PF13600.1 KEP62965.1 - 7.2 7.1 19.7 0.63 10.5 0.9 3.6 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) UQ_con PF00179.21 KEP62967.1 - 5.6e-51 171.6 0.0 7.5e-51 171.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEP62967.1 - 0.00049 19.8 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEP62967.1 - 0.0091 15.8 0.1 0.015 15.2 0.1 1.5 1 1 0 1 1 1 1 RWD domain Ank_2 PF12796.2 KEP62968.1 - 5.9e-41 138.7 3.4 7e-18 64.7 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEP62968.1 - 2.9e-38 127.8 7.6 1.5e-06 27.7 0.0 7.5 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KEP62968.1 - 2.6e-31 104.5 2.9 8.6e-05 22.4 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KEP62968.1 - 8.5e-29 99.4 5.4 3.1e-07 30.7 0.0 6.2 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEP62968.1 - 3.6e-26 90.5 10.2 1.2e-08 34.9 0.0 5.9 4 2 2 6 6 5 5 Ankyrin repeats (many copies) TPR_11 PF13414.1 KEP62968.1 - 7.6e-13 47.9 13.6 3.4e-10 39.4 3.6 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEP62968.1 - 3.4e-06 26.5 1.4 0.012 15.5 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEP62968.1 - 2.9e-05 23.4 1.7 0.047 13.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEP62968.1 - 0.002 18.5 11.0 0.16 12.7 0.7 4.7 3 1 2 5 5 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEP62968.1 - 0.0087 15.9 3.7 0.0087 15.9 2.6 2.4 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP62968.1 - 0.011 15.8 1.3 0.53 10.6 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEP62968.1 - 0.021 14.5 0.1 0.021 14.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 KEP62968.1 - 0.085 12.3 1.9 0.17 11.3 1.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_7 PF13176.1 KEP62968.1 - 0.16 11.8 2.8 0.8 9.6 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEP62968.1 - 2.5 8.8 16.2 0.85 10.3 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEP62968.1 - 10 6.5 12.9 3.6 8.0 4.8 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_M3 PF01432.15 KEP62969.1 - 4.7e-23 81.9 0.0 6.1e-23 81.5 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.5 KEP62969.1 - 0.017 15.1 0.0 0.078 13.0 0.0 2.2 1 0 0 1 1 1 0 Oligopeptidase F DUF3783 PF12646.2 KEP62969.1 - 0.022 14.4 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) NusB PF01029.13 KEP62970.1 - 0.06 13.3 0.9 0.083 12.8 0.6 1.2 1 0 0 1 1 1 0 NusB family Aminotran_5 PF00266.14 KEP62972.1 - 5.6e-122 407.0 0.0 2.4e-103 345.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Sulfate_transp PF00916.15 KEP62973.1 - 0.48 9.3 5.1 0.79 8.6 3.6 1.3 1 0 0 1 1 1 0 Sulfate transporter family DRIM PF07539.7 KEP62976.1 - 1.2e-13 50.6 0.1 4e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 Down-regulated in metastasis NCA2 PF08637.5 KEP62976.1 - 2.3 7.0 0.0 4.8 5.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 AP2 PF00847.15 KEP62977.1 - 4.3e-07 29.9 6.9 7.3e-07 29.2 4.8 1.4 1 0 0 1 1 1 1 AP2 domain TBCC PF07986.7 KEP62978.1 - 4.8e-11 42.1 0.1 8.6e-11 41.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 KEP62978.1 - 0.018 14.3 0.1 0.018 14.3 0.1 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal SMC_N PF02463.14 KEP62979.1 - 5.8e-19 68.1 0.0 9.4e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEP62979.1 - 2.9e-15 57.1 0.0 2.9e-15 57.1 0.0 4.7 2 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 KEP62979.1 - 0.00061 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KEP62979.1 - 0.011 15.7 0.1 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NYD-SP28_assoc PF14775.1 KEP62979.1 - 2.2 8.0 10.5 1 9.0 1.4 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain NTP_transf_3 PF12804.2 KEP62980.1 - 5.3e-11 42.8 0.0 9.9e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KEP62980.1 - 9.7e-09 34.8 0.0 1.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KEP62980.1 - 0.1 12.1 0.2 4 7.0 0.1 2.9 1 1 2 3 3 3 0 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.14 KEP62980.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Methyltransf_31 PF13847.1 KEP62981.1 - 3.8e-07 29.8 0.0 6.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP62981.1 - 5.8e-06 26.8 0.0 9.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP62981.1 - 6.5e-05 23.2 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP62981.1 - 7.7e-05 22.7 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP62981.1 - 0.00021 21.0 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP62981.1 - 0.002 18.6 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP62981.1 - 0.0024 18.3 0.0 0.004 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEP62981.1 - 0.0028 16.7 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF2865 PF11064.3 KEP62981.1 - 0.0077 16.0 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2865) PrmA PF06325.8 KEP62981.1 - 0.044 12.8 0.1 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.8 KEP62981.1 - 0.056 12.7 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Histone methylation protein DOT1 MTS PF05175.9 KEP62981.1 - 0.089 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF167 PF02594.11 KEP62982.1 - 4.6e-24 84.1 0.1 6.4e-24 83.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 DUF3582 PF12122.3 KEP62982.1 - 0.1 12.6 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3582) Guanylate_cyc PF00211.15 KEP62983.1 - 8.9e-08 31.7 0.1 1.7e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Viral_Beta_CD PF04530.7 KEP62983.1 - 0.23 11.6 1.0 9.6 6.3 0.0 3.6 3 1 1 4 4 4 0 Viral Beta C/D like family DUF4245 PF14030.1 KEP62983.1 - 0.46 10.2 1.4 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) Chorein_N PF12624.2 KEP62985.1 - 5.2e-23 80.8 0.3 9.1e-23 80.0 0.2 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF2014 PF09427.5 KEP62985.1 - 0.0073 15.4 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) DUF1162 PF06650.7 KEP62986.1 - 1e-13 51.1 0.0 2.5e-12 46.5 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1162) HAD PF12710.2 KEP62988.1 - 8.8e-13 48.8 0.0 7.4e-12 45.8 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEP62988.1 - 2.1e-11 44.6 0.1 6.8e-05 23.3 0.1 3.7 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEP62988.1 - 1.7e-06 27.2 0.0 1.7e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KEP62988.1 - 0.0026 17.6 0.0 0.93 9.4 0.0 3.4 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEP62988.1 - 0.01 15.4 0.1 0.032 13.7 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SpoU_methylase PF00588.14 KEP62989.1 - 3.9e-23 81.9 0.0 5.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family Rad51 PF08423.6 KEP62990.1 - 2.2e-127 423.3 0.7 3.1e-127 422.8 0.1 1.4 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 KEP62990.1 - 8.9e-10 38.2 0.0 4.9e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 KEP62990.1 - 1.4e-09 37.5 0.1 1.9e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KEP62990.1 - 1.5e-09 37.8 0.3 4.6e-09 36.3 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 KEP62990.1 - 1.1e-05 24.6 0.2 3.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA PF00004.24 KEP62990.1 - 0.00018 21.7 0.1 0.0017 18.5 0.0 2.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HHH PF00633.18 KEP62990.1 - 0.0012 18.4 0.1 0.0028 17.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA_22 PF13401.1 KEP62990.1 - 0.081 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain HHH_6 PF14579.1 KEP62990.1 - 0.12 12.3 0.3 8.6 6.4 0.0 2.4 1 1 0 2 2 2 0 Helix-hairpin-helix motif RabGAP-TBC PF00566.13 KEP62994.1 - 4.7e-37 127.5 0.2 8.7e-37 126.6 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 KEP62994.1 - 0.047 14.0 0.1 0.86 9.9 0.0 2.7 3 0 0 3 3 3 0 Rhodanese-like domain Nop25 PF09805.4 KEP62995.1 - 9.5e-12 45.1 24.1 4.8e-11 42.8 16.8 2.2 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) OTU PF02338.14 KEP62996.1 - 1e-07 32.5 0.0 3.9e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KEP62996.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain Proteasome PF00227.21 KEP62997.1 - 2.4e-36 124.7 0.0 3.8e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEP62997.1 - 1.7e-13 49.5 0.1 3.6e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1664 PF07889.7 KEP62998.1 - 0.045 13.5 0.1 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4131 PF13567.1 KEP62999.1 - 3.5 6.9 5.8 11 5.4 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) NMD3 PF04981.8 KEP63001.1 - 7.3e-59 198.7 7.9 9.8e-59 198.3 5.5 1.2 1 0 0 1 1 1 1 NMD3 family tRNA-synt_1 PF00133.17 KEP63003.1 - 1.5e-46 158.6 1.1 5.5e-17 61.0 0.0 4.4 5 0 0 5 5 5 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEP63003.1 - 0.00019 20.2 0.0 0.88 8.1 0.0 3.6 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEP63003.1 - 0.0022 17.7 0.3 0.0086 15.8 0.1 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Thioredoxin PF00085.15 KEP63004.1 - 0.0047 16.5 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF4313 PF14190.1 KEP63004.1 - 0.013 15.1 0.0 0.088 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4313) RRF PF01765.14 KEP63005.1 - 1.5e-28 99.3 1.0 2.6e-28 98.5 0.7 1.5 1 0 0 1 1 1 1 Ribosome recycling factor DUF4633 PF15464.1 KEP63005.1 - 0.93 9.3 4.8 10 6.0 2.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) Glycos_transf_2 PF00535.21 KEP63006.1 - 1.6e-12 47.4 0.0 1.1e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Methyltransf_8 PF05148.10 KEP63007.1 - 5.1e-66 222.4 0.0 3e-64 216.6 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KEP63007.1 - 9.9e-08 32.3 0.0 2.2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP63007.1 - 0.006 16.3 0.0 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP63007.1 - 0.039 14.4 0.0 0.69 10.4 0.0 2.6 1 1 1 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 KEP63007.1 - 0.046 12.8 0.0 0.12 11.4 0.0 1.6 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KEP63007.1 - 0.049 13.2 0.0 0.77 9.3 0.0 2.4 1 1 2 3 3 3 0 Methyltransferase domain HEAT PF02985.17 KEP63009.1 - 6.9e-24 81.7 20.8 6.8e-05 22.6 0.1 11.8 11 0 0 11 11 10 6 HEAT repeat HEAT_EZ PF13513.1 KEP63009.1 - 8.3e-23 80.2 25.4 2.7e-10 40.3 0.2 10.8 7 3 5 12 12 11 7 HEAT-like repeat HEAT_2 PF13646.1 KEP63009.1 - 2.5e-19 69.3 8.7 0.00013 22.1 0.1 8.1 4 4 4 8 8 8 6 HEAT repeats Cnd1 PF12717.2 KEP63009.1 - 1.4e-11 44.6 0.0 8.2e-06 25.7 0.0 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KEP63009.1 - 2.9e-07 30.0 10.4 0.14 12.0 0.1 7.4 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 KEP63009.1 - 3.4e-07 30.5 0.1 0.22 11.9 0.0 5.0 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KEP63009.1 - 4.5e-06 26.1 0.5 0.21 10.9 0.0 4.6 3 3 0 3 3 3 1 CLASP N terminal IBN_N PF03810.14 KEP63009.1 - 6.7e-06 25.9 1.5 9.2e-05 22.2 0.2 3.5 3 1 1 4 4 4 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KEP63009.1 - 0.00016 20.1 0.1 0.06 11.6 0.1 3.6 3 1 0 3 3 3 1 Adaptin N terminal region DUF2454 PF10521.4 KEP63009.1 - 0.024 13.6 2.0 0.13 11.2 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2454) HEAT_PBS PF03130.11 KEP63009.1 - 8.6 7.1 10.5 5.2 7.8 0.1 6.0 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Exo_endo_phos PF03372.18 KEP63010.1 - 2e-22 80.3 0.1 2.9e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KEP63010.1 - 0.038 13.5 0.0 0.092 12.3 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase FtsJ PF01728.14 KEP63011.1 - 2.9e-18 66.5 0.0 7.9e-18 65.0 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase SNF PF00209.13 KEP63011.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family EF-hand_7 PF13499.1 KEP63012.1 - 3.5e-05 23.8 1.3 0.39 10.9 0.3 3.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEP63012.1 - 0.00043 19.8 2.0 1 9.0 0.5 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP63012.1 - 0.0072 15.5 2.4 0.5 9.7 0.2 3.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KEP63012.1 - 0.0097 15.7 3.6 2.4 8.2 0.2 3.7 2 0 0 2 2 2 2 EF-hand domain DUF912 PF06024.7 KEP63012.1 - 9.8 6.2 4.9 67 3.6 0.9 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Trigger_N PF05697.8 KEP63013.1 - 6.8e-11 42.1 0.0 2.2e-10 40.5 0.0 1.8 2 1 0 2 2 2 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.9 KEP63013.1 - 7.9e-11 42.0 6.9 1.5e-10 41.1 4.8 1.4 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus DUF648 PF04890.8 KEP63013.1 - 0.022 13.9 0.7 0.036 13.2 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) GHMP_kinases_C PF08544.8 KEP63014.1 - 1.3e-07 31.6 0.8 5.5e-07 29.7 0.1 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KEP63014.1 - 0.00042 20.3 2.5 0.00042 20.3 1.7 3.7 4 1 0 4 4 4 1 GHMP kinases N terminal domain SymE_toxin PF08845.5 KEP63014.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system KH_1 PF00013.24 KEP63017.1 - 6.9e-27 92.8 4.7 8.5e-12 44.5 0.9 5.9 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 KEP63017.1 - 5e-15 54.7 0.4 0.00061 19.3 0.8 5.5 5 0 0 5 5 5 3 KH domain BMC PF00936.14 KEP63017.1 - 0.0011 18.5 6.2 0.15 11.7 0.7 4.1 4 0 0 4 4 4 1 BMC domain KH_4 PF13083.1 KEP63017.1 - 0.0062 16.1 0.2 3.7 7.2 0.1 2.8 2 0 0 2 2 2 2 KH domain Pup PF05639.6 KEP63017.1 - 0.0067 16.8 0.9 0.064 13.7 0.0 3.2 2 0 0 2 2 2 1 Pup-like protein KH_2 PF07650.12 KEP63017.1 - 0.087 12.3 8.4 1.5 8.4 0.1 3.3 3 0 0 3 3 3 0 KH domain FlxA PF14282.1 KEP63017.1 - 3.2 7.7 18.8 0.2 11.6 7.3 2.6 2 0 0 2 2 2 0 FlxA-like protein Ank_2 PF12796.2 KEP63018.1 - 3.1e-42 142.7 4.4 9.6e-16 57.9 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEP63018.1 - 2.7e-39 131.0 4.8 8e-09 34.8 0.2 7.4 6 1 1 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KEP63018.1 - 4e-38 129.1 9.7 2.5e-11 43.7 0.1 6.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEP63018.1 - 1.1e-34 117.6 7.5 1.9e-08 34.2 0.0 6.0 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP63018.1 - 4.6e-33 109.9 2.0 9.5e-06 25.3 0.1 7.3 7 0 0 7 7 7 7 Ankyrin repeat DUF2226 PF09987.4 KEP63018.1 - 0.018 14.1 0.0 0.043 12.9 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) DUF912 PF06024.7 KEP63018.1 - 0.041 13.9 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pep_deformylase PF01327.16 KEP63019.1 - 1.5e-43 147.8 0.0 2.2e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 Polypeptide deformylase MFS_1 PF07690.11 KEP63020.1 - 4.1e-15 55.3 28.1 1.8e-13 49.9 12.1 3.1 1 1 1 3 3 3 2 Major Facilitator Superfamily DMAP1 PF05499.7 KEP63021.1 - 0.1 12.1 0.2 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) MCM PF00493.18 KEP63023.1 - 2.8e-106 355.0 0.0 2.4e-104 348.7 0.0 2.2 1 1 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KEP63023.1 - 1.1e-06 27.9 0.1 0.00037 19.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 KEP63023.1 - 8.7e-06 26.2 0.0 5.2e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.6 KEP63023.1 - 0.0034 16.9 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEP63023.1 - 0.014 15.1 0.0 0.079 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KEP63023.1 - 0.07 13.3 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavokinase PF01687.12 KEP63024.1 - 7.6e-26 90.4 0.0 8.1e-19 67.7 0.0 2.2 2 0 0 2 2 2 2 Riboflavin kinase Leo1 PF04004.8 KEP63025.1 - 1.7e-27 96.2 0.2 3.2e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 Leo1-like protein PseudoU_synth_2 PF00849.17 KEP63026.1 - 8.7e-08 32.1 0.0 2.3e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 RNA pseudouridylate synthase VIT1 PF01988.14 KEP63027.1 - 0.02 14.3 0.2 0.031 13.7 0.1 1.3 1 1 0 1 1 1 0 VIT family DUF2562 PF10814.3 KEP63027.1 - 0.066 13.1 3.3 1.8 8.4 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) HUN PF08729.5 KEP63028.1 - 0.025 14.4 1.8 0.073 12.9 1.2 1.7 1 0 0 1 1 1 0 HPC2 and ubinuclein domain ABC_tran PF00005.22 KEP63029.1 - 6.8e-36 123.5 0.0 1e-16 61.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 KEP63029.1 - 2.9e-15 55.5 9.0 4.3e-15 55.0 4.2 2.5 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KEP63029.1 - 2.7e-14 53.8 2.4 0.0069 16.3 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 KEP63029.1 - 7.6e-11 41.6 4.2 0.002 17.4 0.0 3.9 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KEP63029.1 - 1.5e-08 34.1 0.0 0.14 11.1 0.0 4.0 4 0 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 KEP63029.1 - 3e-07 30.6 0.0 0.00021 21.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEP63029.1 - 5.4e-07 29.0 0.2 0.036 13.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4 PF00037.22 KEP63029.1 - 1.9e-06 27.1 4.2 1.9e-06 27.1 2.9 2.4 3 0 0 3 3 1 1 4Fe-4S binding domain DUF258 PF03193.11 KEP63029.1 - 2.8e-06 26.5 2.2 0.0082 15.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEP63029.1 - 4.7e-06 26.7 0.0 0.0028 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4_6 PF12837.2 KEP63029.1 - 4.8e-06 26.2 12.6 4.9e-05 23.0 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain AAA_17 PF13207.1 KEP63029.1 - 2.8e-05 24.8 0.0 0.45 11.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEP63029.1 - 5.8e-05 22.8 0.2 0.012 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 KEP63029.1 - 8.8e-05 21.3 0.0 0.0058 15.3 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 KEP63029.1 - 9e-05 22.1 0.1 0.046 13.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 KEP63029.1 - 0.00013 21.6 0.2 0.052 13.2 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KEP63029.1 - 0.00029 21.1 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEP63029.1 - 0.0004 20.5 0.0 0.45 10.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KEP63029.1 - 0.00056 19.8 0.0 0.071 13.0 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KEP63029.1 - 0.00074 19.4 0.0 0.071 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEP63029.1 - 0.0012 18.9 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Fer4_2 PF12797.2 KEP63029.1 - 0.002 17.9 2.7 0.002 17.9 1.9 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 KEP63029.1 - 0.0023 18.2 1.8 0.0023 18.2 1.3 2.5 1 1 0 2 2 2 1 4Fe-4S dicluster domain Miro PF08477.8 KEP63029.1 - 0.0025 18.3 0.0 0.097 13.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 KEP63029.1 - 0.0042 17.4 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 KEP63029.1 - 0.0042 16.9 11.8 0.0085 15.9 8.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 KEP63029.1 - 0.0046 16.3 0.0 3.7 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 KEP63029.1 - 0.0055 16.1 1.7 0.94 8.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain VirE PF05272.6 KEP63029.1 - 0.0087 15.5 0.1 3.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Virulence-associated protein E SbcCD_C PF13558.1 KEP63029.1 - 0.0091 15.8 0.0 5.7 6.9 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_10 PF13237.1 KEP63029.1 - 0.01 15.5 1.6 0.01 15.5 1.1 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.12 KEP63029.1 - 0.011 15.0 0.0 2.1 7.6 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase UPF0079 PF02367.12 KEP63029.1 - 0.015 14.8 0.1 0.45 10.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KEP63029.1 - 0.016 15.1 0.4 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_3 PF12798.2 KEP63029.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 1 0 4Fe-4S binding domain DUF815 PF05673.8 KEP63029.1 - 0.018 13.9 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 KEP63029.1 - 0.018 14.5 0.0 0.78 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEP63029.1 - 0.025 14.4 0.3 5.1 7.0 0.0 3.1 3 1 0 3 3 2 0 AAA domain Fer4_9 PF13187.1 KEP63029.1 - 0.025 14.8 12.4 0.091 13.0 8.6 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain ArgK PF03308.11 KEP63029.1 - 0.025 13.3 0.2 1.2 7.9 0.1 2.2 2 0 0 2 2 2 0 ArgK protein Fer4_16 PF13484.1 KEP63029.1 - 0.036 14.7 0.7 0.036 14.7 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_10 PF12846.2 KEP63029.1 - 0.042 13.2 0.1 5.1 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Mg_chelatase PF01078.16 KEP63029.1 - 0.055 12.6 0.2 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 KEP63029.1 - 0.064 12.9 0.6 11 5.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_PrkA PF08298.6 KEP63029.1 - 0.086 11.5 0.1 5.1 5.6 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain Arch_ATPase PF01637.13 KEP63029.1 - 0.092 12.4 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_13 PF13166.1 KEP63029.1 - 0.097 11.1 0.6 0.26 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.1 KEP63029.1 - 0.14 12.5 0.3 0.14 12.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 KEP63029.1 - 0.14 10.9 0.1 11 4.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Fer4_8 PF13183.1 KEP63029.1 - 0.19 11.7 9.4 0.13 12.3 0.9 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 KEP63029.1 - 2 8.9 14.0 0.12 12.8 1.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 KEP63029.1 - 7 7.1 10.4 26 5.3 6.8 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF4464 PF14713.1 KEP63030.1 - 5.9e-87 290.9 0.1 6.5e-87 290.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) 5_nucleotid_C PF02872.13 KEP63031.1 - 7.7e-30 103.9 0.0 1.3e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KEP63031.1 - 3e-08 33.3 0.1 1.4e-07 31.0 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEP63031.1 - 0.00023 21.0 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SRP54 PF00448.17 KEP63031.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MFS_1 PF07690.11 KEP63032.1 - 1.1e-33 116.3 23.3 1.1e-33 116.3 16.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEP63032.1 - 1.2e-10 40.6 10.5 1.6e-10 40.1 7.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 KEP63032.1 - 9.7e-05 20.6 0.1 0.068 11.2 0.1 2.6 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 KEP63032.1 - 0.0061 16.3 0.1 0.49 10.2 0.0 3.2 3 0 0 3 3 3 1 MFS_1 like family DTW PF03942.10 KEP63033.1 - 1.8e-18 66.5 0.0 4.4e-18 65.2 0.0 1.6 1 1 0 1 1 1 1 DTW domain IR1-M PF12185.3 KEP63033.1 - 0.025 14.3 0.0 5 6.9 0.0 2.8 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain IBD PF10416.4 KEP63034.1 - 0.11 12.2 0.4 0.21 11.3 0.3 1.4 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD DEAD PF00270.24 KEP63036.1 - 2.7e-35 121.3 0.2 4.4e-35 120.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP63036.1 - 2.2e-26 91.5 0.2 2.7e-25 88.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP63036.1 - 0.0007 19.4 0.1 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KEP63036.1 - 0.0092 15.0 0.1 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ThuA PF06283.6 KEP63036.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation DUF1227 PF06777.6 KEP63037.1 - 1.7e-48 164.0 1.0 4.4e-43 146.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 KEP63037.1 - 4.1e-41 140.7 0.0 8.4e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEP63037.1 - 6.2e-30 103.8 0.0 4.1e-10 39.3 0.0 4.4 4 0 0 4 4 4 4 DEAD_2 ResIII PF04851.10 KEP63037.1 - 3.4e-05 23.7 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEP63037.1 - 0.0063 16.0 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Herpes_capsid PF06112.6 KEP63037.1 - 0.082 12.9 5.5 0.21 11.6 3.8 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SPX PF03105.14 KEP63037.1 - 0.12 12.0 1.5 0.29 10.8 1.0 1.5 1 0 0 1 1 1 0 SPX domain AAA_22 PF13401.1 KEP63037.1 - 0.18 11.9 0.3 13 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF755 PF05501.6 KEP63037.1 - 0.71 9.9 4.5 2 8.5 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) WD40 PF00400.27 KEP63038.1 - 4.9e-58 191.0 32.3 1.3e-14 53.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KEP63038.1 - 7.8e-06 25.7 1.0 0.14 11.8 0.0 3.0 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A VEFS-Box PF09733.4 KEP63038.1 - 0.065 12.8 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein GpcrRhopsn4 PF10192.4 KEP63039.1 - 2.4e-09 36.7 2.6 2.4e-09 36.7 1.8 1.5 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 KEP63039.1 - 8.2e-08 31.5 11.0 1.4e-07 30.7 7.6 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor CIAPIN1 PF05093.8 KEP63040.1 - 1.1e-23 83.2 15.2 5e-23 81.0 10.5 2.0 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Attacin_C PF03769.10 KEP63041.1 - 0.033 14.3 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Attacin, C-terminal region Fis1_TPR_C PF14853.1 KEP63042.1 - 0.46 10.3 0.1 0.46 10.3 0.1 2.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat CTP_transf_2 PF01467.21 KEP63043.1 - 1.4e-19 70.6 0.2 3.2e-19 69.5 0.2 1.7 1 1 0 1 1 1 1 Cytidylyltransferase HA2 PF04408.18 KEP63045.1 - 2.8e-23 81.8 0.0 6.6e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KEP63045.1 - 8.5e-18 64.2 0.0 2.2e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KEP63045.1 - 6.6e-12 45.1 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP63045.1 - 3.3e-07 29.9 0.1 9.6e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KEP63045.1 - 4e-05 22.6 0.0 8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KEP63045.1 - 8.1e-05 22.7 0.4 0.00037 20.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 KEP63045.1 - 0.0019 18.0 0.0 0.0047 16.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KEP63045.1 - 0.0042 17.3 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KEP63045.1 - 0.0049 16.5 0.6 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 KEP63045.1 - 0.0072 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KEP63045.1 - 0.0091 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.1 KEP63045.1 - 0.016 15.5 0.0 0.056 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KEP63045.1 - 0.017 14.4 0.0 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KEP63045.1 - 0.026 14.5 2.0 0.059 13.3 0.0 2.6 4 0 0 4 4 4 0 AAA ATPase domain Herpes_ori_bp PF02399.10 KEP63045.1 - 0.14 10.0 0.0 0.23 9.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein SRP54 PF00448.17 KEP63045.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 KEP63046.1 - 4.2e-31 107.8 0.0 1.2e-30 106.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KEP63046.1 - 1.7e-08 34.4 0.5 4e-08 33.2 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEP63046.1 - 1.1e-05 25.3 0.0 5.4e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KEP63046.1 - 0.0008 19.0 0.1 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 KEP63046.1 - 0.0061 15.7 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KEP63046.1 - 0.014 14.9 0.1 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KEP63046.1 - 0.025 14.0 0.2 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KEP63046.1 - 0.064 13.7 0.0 16 6.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein LRR_4 PF12799.2 KEP63047.1 - 1.9e-08 33.7 9.2 5.9e-06 25.7 0.9 2.8 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP63047.1 - 7.6e-05 22.3 9.3 9e-05 22.1 4.1 2.4 1 1 1 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 KEP63047.1 - 0.00044 19.9 7.6 0.1 12.7 0.6 3.4 2 1 0 2 2 2 2 Leucine Rich Repeat LRR_6 PF13516.1 KEP63047.1 - 0.0041 17.0 5.2 0.87 9.8 0.2 3.2 2 1 0 2 2 2 2 Leucine Rich repeat LRR_7 PF13504.1 KEP63047.1 - 0.018 15.1 10.5 0.58 10.5 0.4 4.0 4 1 0 4 4 4 0 Leucine rich repeat LRR_9 PF14580.1 KEP63047.1 - 0.055 13.0 0.3 0.3 10.6 0.2 2.0 1 1 0 1 1 1 0 Leucine-rich repeat Auto_anti-p27 PF06677.7 KEP63047.1 - 0.095 12.4 0.2 6 6.7 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1900 PF08954.6 KEP63048.1 - 6e-44 148.8 0.0 1e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 KEP63048.1 - 3.1e-12 45.8 4.9 7e-05 22.5 0.0 3.8 4 0 0 4 4 3 2 WD domain, G-beta repeat DUF1899 PF08953.6 KEP63048.1 - 8.5e-07 28.5 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) MAD PF05557.8 KEP63048.1 - 0.0007 17.8 16.9 0.001 17.2 11.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Macoilin PF09726.4 KEP63048.1 - 0.0012 17.1 18.2 0.0017 16.7 12.6 1.1 1 0 0 1 1 1 1 Transmembrane protein TMF_TATA_bd PF12325.3 KEP63048.1 - 0.0024 17.6 17.9 0.0055 16.4 4.0 2.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 KEP63048.1 - 0.017 14.9 24.3 0.025 14.3 7.3 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 KEP63048.1 - 0.028 14.4 26.0 0.66 10.0 8.0 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 KEP63048.1 - 0.037 13.9 30.6 0.21 11.5 5.7 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) YscO PF07321.7 KEP63048.1 - 0.04 13.7 27.5 0.02 14.6 5.6 2.5 2 0 0 2 2 2 0 Type III secretion protein YscO HALZ PF02183.13 KEP63048.1 - 0.05 13.3 30.5 0.095 12.4 1.9 5.8 3 2 2 5 5 5 0 Homeobox associated leucine zipper eIF2A PF08662.6 KEP63048.1 - 0.066 12.9 0.1 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Reo_sigmaC PF04582.7 KEP63048.1 - 0.077 12.1 8.2 0.055 12.6 3.6 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KEP63048.1 - 0.08 12.5 28.0 0.3 10.6 12.9 2.3 1 1 1 2 2 2 0 IncA protein Mto2_bdg PF12808.2 KEP63048.1 - 0.11 12.5 33.6 0.04 14.0 3.2 4.9 3 2 2 5 5 5 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.10 KEP63048.1 - 0.14 11.6 34.7 0.019 14.4 3.5 4.6 2 2 2 4 4 4 0 Septum formation initiator DUF4201 PF13870.1 KEP63048.1 - 0.14 11.5 21.3 0.069 12.5 3.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) AAA_13 PF13166.1 KEP63048.1 - 0.15 10.4 14.4 0.22 9.9 10.0 1.1 1 0 0 1 1 1 0 AAA domain PilJ PF13675.1 KEP63048.1 - 0.2 11.9 17.7 0.085 13.1 3.7 2.7 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2408 PF10303.4 KEP63048.1 - 0.21 11.7 14.7 3.5 7.7 6.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) GAS PF13851.1 KEP63048.1 - 0.23 10.6 26.7 5.1 6.2 17.1 3.1 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KEP63048.1 - 0.31 10.7 29.6 2.4 7.8 10.8 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ax_dynein_light PF10211.4 KEP63048.1 - 0.35 10.6 18.7 2.2 8.0 1.8 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain TSC22 PF01166.13 KEP63048.1 - 0.46 10.4 18.8 0.46 10.4 0.3 4.6 2 1 2 4 4 4 0 TSC-22/dip/bun family Occludin_ELL PF07303.8 KEP63048.1 - 0.46 11.2 10.2 0.11 13.2 1.7 2.6 2 1 1 3 3 3 0 Occludin homology domain TMPIT PF07851.8 KEP63048.1 - 0.68 8.9 10.1 0.43 9.6 4.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Laminin_II PF06009.7 KEP63048.1 - 0.93 9.2 15.9 1.8 8.2 0.9 2.6 3 0 0 3 3 2 0 Laminin Domain II Phage_GP20 PF06810.6 KEP63048.1 - 1.2 8.5 23.3 2.8 7.3 8.7 3.2 2 1 2 4 4 4 0 Phage minor structural protein GP20 DUF3573 PF12097.3 KEP63048.1 - 1.4 7.4 8.0 1.7 7.1 0.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3573) NYD-SP28_assoc PF14775.1 KEP63048.1 - 1.5 8.5 20.2 1.2 8.8 2.0 3.9 3 0 0 3 3 3 0 Sperm tail C-terminal domain Herpes_BLRF2 PF05812.7 KEP63048.1 - 1.6 8.5 29.4 0.11 12.2 0.6 4.3 3 1 2 5 5 4 0 Herpesvirus BLRF2 protein CENP-F_leu_zip PF10473.4 KEP63048.1 - 1.8 8.4 29.9 0.43 10.4 6.2 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 KEP63048.1 - 4.6 7.7 24.9 1.2 9.5 2.9 3.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) AKNA PF12443.3 KEP63048.1 - 6.3 6.8 11.5 14 5.7 0.6 3.3 1 1 1 3 3 3 0 AT-hook-containing transcription factor Mnd1 PF03962.10 KEP63048.1 - 9.7 5.8 25.1 2.4 7.8 7.2 2.3 1 1 1 2 2 2 0 Mnd1 family WD40 PF00400.27 KEP63049.1 - 4.4e-09 35.8 3.9 3.6 7.6 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KEP63049.1 - 0.00027 20.7 0.0 5.1 6.7 0.0 4.4 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 KEP63049.1 - 0.018 14.7 0.3 0.018 14.7 0.2 3.2 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term LysM PF01476.15 KEP63050.1 - 1.7e-05 24.6 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain GYF PF02213.11 KEP63052.1 - 0.0059 16.1 0.1 0.017 14.6 0.1 1.8 2 0 0 2 2 2 1 GYF domain HTH_AsnC-type PF13404.1 KEP63052.1 - 0.037 13.5 0.1 0.037 13.5 0.1 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain AFG1_ATPase PF03969.11 KEP63053.1 - 5e-89 298.6 0.3 4.1e-86 289.0 0.1 3.1 3 0 0 3 3 3 1 AFG1-like ATPase AAA PF00004.24 KEP63053.1 - 0.00018 21.7 0.0 0.0049 17.0 0.0 3.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 KEP63053.1 - 0.0016 18.1 0.1 0.0059 16.2 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.1 KEP63053.1 - 0.0045 17.1 0.1 0.6 10.2 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEP63053.1 - 0.032 14.1 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEP63053.1 - 0.06 13.0 0.3 0.71 9.5 0.2 2.3 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 KEP63053.1 - 0.087 12.4 0.1 0.47 10.0 0.0 2.3 2 1 1 3 3 3 0 NACHT domain DnaI_N PF07319.6 KEP63053.1 - 0.094 12.9 1.2 0.51 10.6 0.1 2.4 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus UvrD-helicase PF00580.16 KEP63053.1 - 0.18 11.0 2.1 7.8 5.6 0.0 2.4 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1674 PF07896.7 KEP63054.1 - 1e-09 38.4 1.1 2.4e-09 37.2 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) PsaD PF02531.11 KEP63054.1 - 0.049 12.8 0.0 0.15 11.2 0.0 1.8 2 1 0 2 2 2 0 PsaD Myb_DNA-binding PF00249.26 KEP63056.1 - 6.6e-10 38.8 0.2 8.8e-09 35.2 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.12 KEP63056.1 - 3.1e-08 33.0 10.1 5.6e-08 32.2 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 KEP63056.1 - 2.8e-06 27.3 0.3 6.4e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain DER1 PF04511.10 KEP63057.1 - 8.2e-40 136.4 14.1 9.2e-40 136.2 9.8 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 KEP63057.1 - 3.2e-05 23.9 17.5 5.6e-05 23.1 12.1 1.4 1 0 0 1 1 1 1 Rhomboid family RdRP PF05183.7 KEP63059.1 - 4.3e-133 445.0 0.0 4.5e-116 388.8 0.0 3.2 2 1 0 2 2 2 2 RNA dependent RNA polymerase zf-C3HC4_3 PF13920.1 KEP63060.1 - 6.5e-09 35.3 11.4 1.2e-08 34.4 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP63060.1 - 2.3e-07 30.7 12.5 4.7e-07 29.7 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP63060.1 - 1.6e-06 27.6 13.0 3.7e-06 26.4 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP63060.1 - 7.8e-05 22.4 10.9 0.00016 21.3 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEP63060.1 - 0.00022 20.8 13.2 0.00049 19.7 9.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEP63060.1 - 0.00078 19.1 7.3 0.0029 17.3 5.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KEP63060.1 - 0.00082 18.9 8.8 0.0017 17.8 6.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KEP63060.1 - 0.0014 18.4 8.5 0.0043 16.8 5.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KEP63060.1 - 0.0061 16.6 4.6 0.017 15.2 3.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 KEP63060.1 - 0.034 13.7 5.0 0.098 12.2 3.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.1 KEP63060.1 - 0.091 12.5 5.1 0.24 11.1 3.5 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.2 KEP63060.1 - 1.2 9.0 6.7 4.4 7.1 4.6 2.0 1 0 0 1 1 1 0 Double zinc ribbon DUF3728 PF12528.3 KEP63062.1 - 0.002 18.4 4.3 0.94 9.9 0.2 3.9 4 0 0 4 4 4 2 Prepilin peptidase dependent protein C (DUF3728) Inhibitor_I42 PF09394.5 KEP63062.1 - 0.034 14.4 0.0 17 5.8 0.0 2.7 3 0 0 3 3 3 0 Chagasin family peptidase inhibitor I42 Inhibitor_I42 PF09394.5 KEP63063.1 - 0.00012 22.2 0.0 53 4.2 0.0 5.0 5 0 0 5 5 5 3 Chagasin family peptidase inhibitor I42 Sas10 PF09368.5 KEP63065.1 - 9.3e-23 80.2 5.6 9.3e-23 80.2 3.9 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KEP63065.1 - 1.7e-21 76.2 0.7 7.9e-21 74.0 0.5 2.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Prenyltransf PF01255.14 KEP63067.1 - 1.1e-53 181.7 0.0 2e-53 180.8 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DEAD PF00270.24 KEP63069.1 - 2.7e-17 62.7 0.0 6.1e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 KEP63069.1 - 6.3e-09 35.3 0.2 0.00031 19.9 0.2 2.4 2 0 0 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.26 KEP63069.1 - 0.0014 18.4 0.1 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DNA_pol_phi PF04931.8 KEP63069.1 - 2.9 5.5 14.8 5 4.7 10.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi HECT PF00632.20 KEP63071.1 - 4.5e-72 242.8 0.0 6.3e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.13 KEP63071.1 - 6.4e-28 96.7 7.4 5.8e-11 42.4 0.1 6.9 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP63071.1 - 6.7e-23 79.7 23.1 9.9e-09 34.5 0.2 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KEP63071.1 - 0.097 12.1 0.1 33 4.0 0.0 3.5 3 0 0 3 3 3 0 Putative carbohydrate binding domain Ribosomal_L11 PF00298.14 KEP63072.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain LMF1 PF06762.9 KEP63073.1 - 1.8e-76 257.4 0.5 3e-76 256.7 0.3 1.3 1 0 0 1 1 1 1 Lipase maturation factor DoxX PF07681.7 KEP63073.1 - 1.3e-06 28.7 0.7 1.3e-06 28.7 0.5 2.6 3 0 0 3 3 3 1 DoxX IBN_N PF03810.14 KEP63077.1 - 3.2e-05 23.7 1.9 5.9e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain SAG PF04092.8 KEP63078.1 - 4.8e-08 33.4 17.5 5.3e-08 33.2 0.4 4.1 4 0 0 4 4 4 3 SRS domain DUF2042 PF09743.4 KEP63079.1 - 9.7e-73 244.8 0.1 1.3e-72 244.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) FeoC PF09012.5 KEP63079.1 - 0.00011 21.8 0.4 2.5 7.8 0.0 4.2 5 0 0 5 5 5 2 FeoC like transcriptional regulator PCI PF01399.22 KEP63079.1 - 0.00051 20.3 1.4 0.018 15.3 0.0 3.3 1 1 1 2 2 2 1 PCI domain HTH_9 PF08221.6 KEP63079.1 - 0.0021 17.8 0.2 1.1 9.1 0.0 3.0 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain Rrf2 PF02082.15 KEP63079.1 - 0.06 13.4 1.5 33 4.6 0.0 3.8 4 0 0 4 4 4 0 Transcriptional regulator FolB PF02152.13 KEP63079.1 - 0.062 13.4 0.5 1.4 9.1 0.1 2.8 2 1 0 2 2 2 0 Dihydroneopterin aldolase DUF3245 PF11595.3 KEP63079.1 - 3.8 7.7 11.7 0.63 10.3 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Spc97_Spc98 PF04130.8 KEP63080.1 - 0.012 14.0 0.8 0.02 13.2 0.0 1.7 2 1 0 2 2 2 0 Spc97 / Spc98 family Baculo_PEP_C PF04513.7 KEP63080.1 - 0.65 9.8 3.9 11 5.8 0.6 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT46_B_C PF12317.3 KEP63080.1 - 1.3 8.3 7.2 0.44 9.8 0.1 2.5 2 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal GSCFA PF08885.6 KEP63080.1 - 3.4 7.1 7.0 12 5.3 0.9 2.4 2 0 0 2 2 2 0 GSCFA family Nol1_Nop2_Fmu PF01189.12 KEP63081.1 - 1.1e-15 57.7 0.0 7.5e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 KEP63081.1 - 2.1e-05 24.5 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 KEP63081.1 - 0.01 15.4 0.0 0.95 9.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Metallophos_C PF14008.1 KEP63081.1 - 0.019 15.0 0.3 9.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Iron/zinc purple acid phosphatase-like protein C Methyltransf_26 PF13659.1 KEP63081.1 - 0.021 14.8 0.1 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 KEP63081.1 - 0.039 13.4 0.0 0.46 9.9 0.0 2.5 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1084 PF06454.6 KEP63083.1 - 5.4e-14 51.9 3.5 1e-13 50.9 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF1129 PF06570.6 KEP63083.1 - 0.00014 21.2 0.1 0.00031 20.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) CcmD PF04995.9 KEP63083.1 - 0.03 14.0 0.6 0.03 14.0 0.4 3.7 4 0 0 4 4 4 0 Heme exporter protein D (CcmD) HoxA13_N PF12284.3 KEP63083.1 - 0.25 11.5 2.1 0.68 10.0 1.4 1.7 1 0 0 1 1 1 0 Hox protein A13 N terminal RseC_MucC PF04246.7 KEP63083.1 - 4.7 6.7 6.2 15 5.1 1.6 2.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC LSM PF01423.17 KEP63085.1 - 6.3e-12 44.8 0.1 9.9e-12 44.2 0.1 1.3 1 0 0 1 1 1 1 LSM domain DUF4282 PF14110.1 KEP63088.1 - 3.3 7.9 5.9 4.7 7.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) FHA PF00498.21 KEP63089.1 - 0.0097 16.0 0.1 0.26 11.4 0.0 2.6 2 1 0 2 2 2 1 FHA domain MMS19_N PF14500.1 KEP63092.1 - 3.1e-34 118.4 0.0 4.5e-30 104.8 0.0 3.1 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II BTV_NS2 PF04514.7 KEP63092.1 - 0.49 9.2 1.7 1.1 8.0 1.2 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Band_7 PF01145.20 KEP63094.1 - 9.7e-32 110.3 0.1 1.5e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KEP63094.1 - 0.011 15.2 0.1 0.049 13.1 0.0 2.1 2 1 1 3 3 3 0 SPFH domain-Band 7 family META PF03724.11 KEP63094.1 - 0.076 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 META domain LMBR1 PF04791.11 KEP63095.1 - 3.2e-24 85.3 15.0 5.2e-22 78.0 10.4 2.2 1 1 0 1 1 1 1 LMBR1-like membrane protein Sigma_reg_N PF13800.1 KEP63095.1 - 0.22 11.5 0.4 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF384 PF04064.8 KEP63096.1 - 1.7e-12 46.7 0.1 1.6e-11 43.6 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Ribosomal_L36 PF00444.13 KEP63098.1 - 0.00044 20.1 0.1 0.00044 20.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L36 Aldedh PF00171.17 KEP63100.1 - 5.9e-177 588.6 0.0 6.9e-177 588.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEP63100.1 - 0.00014 21.1 0.1 0.0019 17.4 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DEAD PF00270.24 KEP63102.1 - 1.3e-35 122.3 0.0 7.6e-32 110.1 0.0 3.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP63102.1 - 2.2e-22 78.7 3.0 2.6e-22 78.4 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.7 KEP63102.1 - 0.00068 19.5 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain DUF1253 PF06862.7 KEP63102.1 - 0.041 12.2 0.0 0.49 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) RNHCP PF12647.2 KEP63103.1 - 0.0015 18.3 0.4 2.2 8.1 0.0 3.1 3 0 0 3 3 3 1 RNHCP domain UPF0167 PF03691.9 KEP63103.1 - 0.036 13.4 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) DNA_RNApol_7kD PF03604.8 KEP63103.1 - 0.04 13.3 5.2 12 5.5 0.1 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit GFA PF04828.9 KEP63103.1 - 0.052 13.4 2.9 0.84 9.6 0.2 2.6 1 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2_2 PF12756.2 KEP63103.1 - 0.059 13.4 0.5 0.16 12.0 0.0 1.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Nudix_N_2 PF14803.1 KEP63103.1 - 0.12 12.1 5.2 3.5 7.3 0.1 3.3 3 0 0 3 3 3 0 Nudix N-terminal Yippee-Mis18 PF03226.9 KEP63103.1 - 0.26 11.3 1.5 0.37 10.8 0.1 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CpXC PF14353.1 KEP63103.1 - 0.51 10.3 2.5 5 7.0 0.0 2.5 2 1 0 2 2 2 0 CpXC protein Rpr2 PF04032.11 KEP63103.1 - 1.5 8.7 4.8 0.71 9.7 1.4 1.9 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 KEP63103.1 - 3.2 7.6 6.0 2.6 7.9 0.6 2.7 2 2 0 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.1 KEP63103.1 - 5.4 7.5 6.6 0.95 9.9 0.2 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger PseudoU_synth_2 PF00849.17 KEP63104.1 - 3e-07 30.4 0.0 1.2e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 RNA pseudouridylate synthase CsbD PF05532.7 KEP63104.1 - 0.28 10.8 0.0 0.28 10.8 0.0 2.4 2 0 0 2 2 2 0 CsbD-like PUB PF09409.5 KEP63105.1 - 6e-16 57.9 0.0 1.5e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 PUB domain UBA PF00627.26 KEP63105.1 - 0.00025 20.7 0.1 0.0047 16.7 0.1 2.6 1 1 0 1 1 1 1 UBA/TS-N domain AAA_11 PF13086.1 KEP63105.1 - 0.27 10.7 4.3 0.41 10.1 3.0 1.4 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 KEP63105.1 - 4.2 5.1 11.8 4.9 4.8 8.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM178 PF14816.1 KEP63105.1 - 6.9 5.2 18.2 0.19 10.3 3.9 2.1 1 1 1 2 2 2 0 Family of unknown function, FAM178 DHFR_1 PF00186.14 KEP63106.1 - 0.035 13.6 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrofolate reductase Ribonuc_red_lgN PF00317.16 KEP63106.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Rab5ip PF07019.7 KEP63107.1 - 9.6e-11 41.6 8.1 1.5e-10 41.0 5.6 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SNAPc19 PF15497.1 KEP63108.1 - 0.081 13.1 0.3 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF1509 PF07420.6 KEP63108.1 - 0.088 12.0 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) GTP_EFTU PF00009.22 KEP63111.1 - 2.6e-37 128.1 0.0 3.9e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEP63111.1 - 0.00012 22.1 0.1 0.00027 21.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KEP63111.1 - 0.00015 21.6 0.0 0.00045 20.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEP63111.1 - 0.014 15.9 0.0 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU_D2 PF03144.20 KEP63111.1 - 0.033 14.3 0.4 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 SRPRB PF09439.5 KEP63111.1 - 0.074 12.2 0.0 3.4 6.8 0.0 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KEP63111.1 - 0.13 12.0 0.3 0.91 9.3 0.1 2.1 1 1 1 2 2 2 0 Dynamin family Septin PF00735.13 KEP63111.1 - 0.22 10.4 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Septin Ion_trans PF00520.26 KEP63112.1 - 2e-15 56.5 28.8 2e-15 56.5 20.0 1.7 2 0 0 2 2 2 1 Ion transport protein Mog1 PF04603.7 KEP63114.1 - 3.2e-28 98.4 0.0 5.6e-28 97.6 0.0 1.3 1 1 0 1 1 1 1 Ran-interacting Mog1 protein DOT1 PF08123.8 KEP63115.1 - 0.0035 16.6 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PGK PF00162.14 KEP63116.1 - 2.8e-149 496.8 0.1 3.7e-149 496.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase TMP-TENI PF02581.12 KEP63116.1 - 0.09 11.8 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI NIF PF03031.13 KEP63117.1 - 6.4e-23 81.1 0.1 1.1e-22 80.3 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Brix PF04427.13 KEP63118.1 - 3.5e-33 114.8 0.0 4.9e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain BSP_II PF05432.6 KEP63118.1 - 0.0024 17.1 20.5 0.0034 16.7 14.2 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) LAT PF15234.1 KEP63118.1 - 0.049 13.0 4.3 0.098 12.1 3.0 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells RXT2_N PF08595.6 KEP63118.1 - 0.07 12.9 6.9 0.16 11.7 4.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 KEP63118.1 - 0.074 12.2 9.1 0.022 14.0 4.5 1.5 2 0 0 2 2 2 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.3 KEP63118.1 - 0.11 12.3 15.2 0.023 14.6 8.2 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 eIF-3c_N PF05470.7 KEP63118.1 - 0.2 9.7 4.4 0.29 9.1 3.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nucleoplasmin PF03066.10 KEP63118.1 - 0.26 10.7 16.1 0.46 10.0 11.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC27 PF09507.5 KEP63118.1 - 0.41 9.8 20.7 0.79 8.8 14.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 KEP63118.1 - 0.41 8.6 8.2 0.61 8.0 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 KEP63118.1 - 0.69 7.5 3.6 0.88 7.1 2.5 1.2 1 0 0 1 1 1 0 Ycf1 PPP4R2 PF09184.6 KEP63118.1 - 1.1 8.7 17.3 1.8 8.0 12.0 1.4 1 0 0 1 1 1 0 PPP4R2 GEMIN8 PF15348.1 KEP63118.1 - 1.5 8.8 15.8 1.2 9.0 5.5 2.5 3 0 0 3 3 2 0 Gemini of Cajal bodies-associated protein 8 Paf1 PF03985.8 KEP63118.1 - 1.5 7.4 15.3 2.5 6.7 10.6 1.3 1 0 0 1 1 1 0 Paf1 FLO_LFY PF01698.11 KEP63118.1 - 3.5 6.3 11.6 6.2 5.5 8.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Pox_RNA_Pol_19 PF05320.7 KEP63118.1 - 4.6 6.9 9.5 9.5 5.9 6.6 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Senescence_reg PF04520.8 KEP63118.1 - 8.3 6.8 18.9 47 4.4 13.1 2.1 1 1 0 1 1 1 0 Senescence regulator Hid1 PF12722.2 KEP63118.1 - 8.5 3.9 5.4 11 3.5 3.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Radial_spoke PF04712.7 KEP63118.1 - 9.7 4.8 16.4 17 3.9 11.4 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein WW PF00397.21 KEP63120.1 - 3.9e-08 33.0 1.2 6.8e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 WW domain zf-U1 PF06220.7 KEP63120.1 - 8.5e-06 25.2 1.3 1.4e-05 24.5 0.9 1.4 1 0 0 1 1 1 1 U1 zinc finger AKAP95 PF04988.7 KEP63120.1 - 0.035 13.8 0.6 0.057 13.2 0.4 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF2246 PF10229.4 KEP63120.1 - 0.059 12.6 0.7 0.13 11.5 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) DUF2423 PF10338.4 KEP63121.1 - 6.9e-12 45.1 0.7 6.9e-12 45.1 0.5 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) DUF3449 PF11931.3 KEP63122.1 - 6.5e-78 260.7 0.9 6.5e-78 260.7 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KEP63122.1 - 1.6e-08 33.9 0.1 5.4e-08 32.2 0.1 1.9 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 KEP63122.1 - 0.0017 18.4 0.1 0.061 13.4 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEP63122.1 - 0.0024 18.0 0.2 1 9.6 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Chlorosome_CsmC PF11098.3 KEP63122.1 - 0.071 12.8 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C Desulfoferrod_N PF06397.7 KEP63122.1 - 0.12 11.7 0.2 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Adaptin_N PF01602.15 KEP63123.1 - 5.5e-48 163.5 0.0 6.4e-43 146.8 0.0 3.3 2 2 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 KEP63123.1 - 0.00044 20.4 0.9 0.00044 20.4 0.7 4.4 5 1 0 5 5 5 1 HEAT repeats NifU PF01106.12 KEP63125.1 - 2.3e-18 65.7 0.0 9.7e-16 57.3 0.0 2.5 2 1 0 2 2 2 2 NifU-like domain Methyltransf_11 PF08241.7 KEP63126.1 - 2.8e-06 27.7 0.0 0.02 15.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KEP63126.1 - 0.0011 18.7 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KEP63126.1 - 0.0046 16.5 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP63126.1 - 0.007 16.8 0.0 0.76 10.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Filament_head PF04732.9 KEP63126.1 - 2.7 8.7 11.2 0.63 10.7 5.3 1.7 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region KAR9 PF08580.5 KEP63126.1 - 2.7 6.1 5.7 3.6 5.7 4.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF605 PF04652.11 KEP63126.1 - 9.6 5.4 11.4 13 5.0 7.9 1.1 1 0 0 1 1 1 0 Vta1 like zf-AN1 PF01428.11 KEP63127.1 - 5.2e-12 45.4 7.1 5.2e-12 45.4 4.9 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.11 KEP63127.1 - 6.9e-12 44.7 6.3 6.9e-12 44.7 4.4 2.3 3 0 0 3 3 3 1 A20-like zinc finger DUF4428 PF14471.1 KEP63127.1 - 0.01 15.5 4.3 1 9.1 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) RAP1 PF07218.6 KEP63127.1 - 7.4 4.5 14.8 8.8 4.2 10.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ATG16 PF08614.6 KEP63129.1 - 0.00089 19.1 0.5 0.87 9.3 0.1 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) WD40 PF00400.27 KEP63130.1 - 1.6e-14 53.1 24.9 0.00013 21.7 0.1 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat Glyco_hydro_63 PF03200.11 KEP63131.1 - 0.91 7.2 1.0 1.3 6.8 0.7 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase CXCL17 PF15211.1 KEP63132.1 - 0.34 11.3 7.6 0.067 13.5 1.9 1.9 1 1 1 2 2 2 0 VEGF co-regulated chemokine 1 Band_7 PF01145.20 KEP63134.1 - 1.8e-08 34.5 0.2 2.2e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Phage_antiter_Q PF06323.6 KEP63135.1 - 0.014 14.8 0.1 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Phage antitermination protein Q Peptidase_S8 PF00082.17 KEP63136.1 - 2.3e-48 164.7 1.6 5e-48 163.6 1.1 1.6 1 0 0 1 1 1 1 Subtilase family PAN_1 PF00024.21 KEP63136.1 - 2.9e-05 23.7 0.0 6.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 PAN domain DUF3251 PF11622.3 KEP63136.1 - 0.088 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) PAN_4 PF14295.1 KEP63136.1 - 0.097 12.3 0.3 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.6 KEP63136.1 - 0.25 11.1 0.0 0.59 10.0 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_3 PF08277.7 KEP63136.1 - 0.56 9.8 0.1 1.5 8.5 0.1 1.6 1 0 0 1 1 1 0 PAN-like domain RabGAP-TBC PF00566.13 KEP63137.1 - 1.4e-36 125.9 3.2 1.4e-36 125.9 2.2 2.8 4 0 0 4 4 4 1 Rab-GTPase-TBC domain DUF846 PF05832.7 KEP63139.1 - 6.6e-43 145.8 12.5 8.5e-43 145.4 8.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) PRA1 PF03208.14 KEP63139.1 - 0.37 10.1 6.5 0.93 8.8 0.8 2.2 2 0 0 2 2 2 0 PRA1 family protein SPT16 PF08644.6 KEP63143.1 - 8.2e-39 132.8 0.0 8.2e-39 132.8 0.0 4.2 3 2 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 KEP63143.1 - 2.4e-21 76.2 0.0 4.5e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.1 KEP63143.1 - 2.3e-19 69.4 0.0 2.3e-19 69.4 0.0 2.9 4 0 0 4 4 4 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 KEP63143.1 - 1.7e-18 66.3 0.1 9.7e-18 63.9 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF1204 PF06721.6 KEP63144.1 - 6.6 5.9 10.3 0.3 10.3 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) DEAD PF00270.24 KEP63145.1 - 2.2e-41 141.1 0.0 5.6e-41 139.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP63145.1 - 3.1e-21 75.0 0.1 8.4e-21 73.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Gly-zipper_OmpA PF13436.1 KEP63146.1 - 0.0073 15.9 9.3 0.023 14.3 6.5 1.8 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 KEP63146.1 - 0.55 9.9 28.2 1.5 8.5 19.5 1.8 1 0 0 1 1 1 0 Glycine zipper AAA_13 PF13166.1 KEP63147.1 - 6.7 5.0 14.5 11 4.2 10.1 1.3 1 0 0 1 1 1 0 AAA domain Tubulin PF00091.20 KEP63148.1 - 1.3e-70 237.6 0.0 2e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEP63148.1 - 2.1e-49 166.7 0.1 3.2e-49 166.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEP63148.1 - 4.5e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KEP63148.1 - 0.0061 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain UCH PF00443.24 KEP63149.1 - 1.1e-29 103.3 0.0 2.5e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP63149.1 - 1.7e-07 30.9 0.0 0.0003 20.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Oligomerisation PF02410.10 KEP63150.1 - 2.6e-13 49.8 0.1 4.5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Oligomerisation domain DSPc PF00782.15 KEP63151.1 - 2.6e-18 65.8 0.0 3.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEP63151.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KEP63151.1 - 0.034 13.6 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) FtsJ PF01728.14 KEP63153.1 - 1e-16 61.4 0.0 4.9e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 FtsJ-like methyltransferase SNF PF00209.13 KEP63153.1 - 0.61 8.4 0.0 0.92 7.8 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family RRM_6 PF14259.1 KEP63154.1 - 0.008 16.1 0.0 0.021 14.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP63154.1 - 0.019 14.6 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rb_C PF08934.5 KEP63154.1 - 0.023 14.3 0.2 0.023 14.3 0.1 1.8 2 0 0 2 2 2 0 Rb C-terminal domain PUA PF01472.15 KEP63154.1 - 0.091 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 PUA domain IFR3_antag PF14754.1 KEP63154.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Papain-like auto-proteinase Pkinase PF00069.20 KEP63156.1 - 1.5e-25 89.8 0.0 1.3e-09 37.5 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63156.1 - 6.2e-11 41.8 0.0 1.3e-06 27.6 0.0 3.4 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KEP63156.1 - 0.0047 16.6 0.3 0.056 13.1 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEP63156.1 - 0.025 13.7 0.0 0.088 11.9 0.0 1.8 2 0 0 2 2 2 0 Ecdysteroid kinase Seadorna_VP7 PF07387.6 KEP63156.1 - 0.38 9.5 0.0 0.59 8.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUSP PF06337.7 KEP63157.1 - 2.5e-07 31.0 0.0 6.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 DUSP domain MORN PF02493.15 KEP63157.1 - 1.4 8.8 12.2 2.1 8.2 0.3 4.1 4 0 0 4 4 4 0 MORN repeat Adap_comp_sub PF00928.16 KEP63159.1 - 8e-07 28.4 0.0 3.5e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family DSPc PF00782.15 KEP63161.1 - 3.6e-22 78.3 0.0 2.4e-21 75.7 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEP63161.1 - 0.0038 16.5 0.0 0.0062 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PUA PF01472.15 KEP63162.1 - 7.9e-16 57.5 0.0 1.2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 PUA domain Herpes_gE PF02480.11 KEP63163.1 - 0.0036 15.6 0.0 0.0045 15.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 KEP63163.1 - 0.0098 15.6 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Nucleoside_tran PF01733.13 KEP63163.1 - 0.023 13.8 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter Trp_oprn_chp PF09534.5 KEP63163.1 - 0.033 13.8 0.2 0.045 13.3 0.2 1.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Flavi_NS2B PF01002.14 KEP63163.1 - 0.068 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B gpUL132 PF11359.3 KEP63163.1 - 0.085 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Neur_chan_memb PF02932.11 KEP63163.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region His_Phos_1 PF00300.17 KEP63165.1 - 1.1e-11 45.0 0.0 4.6e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SPRY PF00622.23 KEP63166.1 - 2.5e-07 30.8 0.0 0.033 14.2 0.0 2.7 2 1 0 2 2 2 2 SPRY domain Kinesin PF00225.18 KEP63169.1 - 7.5e-104 347.0 0.3 2.4e-103 345.3 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain KIF1B PF12423.3 KEP63169.1 - 2.2e-11 43.6 1.9 5.8e-11 42.2 0.2 2.6 3 0 0 3 3 3 1 Kinesin protein 1B FHA PF00498.21 KEP63169.1 - 1.8e-06 27.9 0.1 8.5e-06 25.8 0.0 2.3 3 0 0 3 3 3 1 FHA domain OmpH PF03938.9 KEP63169.1 - 0.002 18.0 28.7 0.1 12.5 2.3 2.4 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) C2 PF00168.25 KEP63169.1 - 0.013 15.2 0.0 0.043 13.6 0.0 1.9 1 0 0 1 1 1 0 C2 domain SYF2 PF08231.7 KEP63169.1 - 0.06 13.4 18.1 0.42 10.7 8.0 2.5 2 0 0 2 2 2 0 SYF2 splicing factor Fmp27_WPPW PF10359.4 KEP63169.1 - 1.2 7.4 17.4 0.14 10.5 1.7 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Actin PF00022.14 KEP63170.1 - 2.6e-42 144.6 0.0 2e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KEP63170.1 - 0.00065 18.3 0.0 0.0041 15.7 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Viral_DNA_bp PF00747.12 KEP63171.1 - 1.4 6.0 0.0 2.2 5.3 0.0 1.2 1 0 0 1 1 1 0 ssDNA binding protein tRNA-synt_1e PF01406.14 KEP63172.1 - 0.078 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF1664 PF07889.7 KEP63172.1 - 0.15 11.9 5.2 0.034 13.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.7 KEP63172.1 - 0.18 11.6 5.0 0.092 12.5 0.2 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Alba PF01918.16 KEP63173.1 - 1.1e-17 63.3 0.5 1.6e-17 62.8 0.3 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 KEP63173.1 - 0.00054 19.6 0.1 0.00069 19.2 0.1 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P APG6 PF04111.7 KEP63175.1 - 2.4e-65 220.6 0.0 2.2e-60 204.3 0.0 2.1 2 0 0 2 2 2 2 Autophagy protein Apg6 DUF1759 PF03564.10 KEP63175.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Ctr PF04145.10 KEP63176.1 - 1.6e-21 76.8 1.3 2.9e-09 37.1 1.6 2.2 2 0 0 2 2 2 2 Ctr copper transporter family CRAL_TRIO PF00650.15 KEP63177.1 - 4.1e-07 29.6 0.0 6.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DNA_topoisoIV PF00521.15 KEP63178.1 - 1.3e-127 426.2 0.0 6.6e-127 423.8 0.0 2.0 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.8 KEP63178.1 - 2.4e-26 90.7 16.3 4.5e-09 35.4 0.2 6.5 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Spore_coat_CotO PF14153.1 KEP63178.1 - 0.0055 16.1 12.6 0.0055 16.1 8.7 4.6 5 1 1 6 6 6 1 Spore coat protein CotO Carboxyl_trans PF01039.17 KEP63179.1 - 2.4e-150 501.1 0.0 4e-150 500.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 KEP63179.1 - 1.6e-133 446.3 0.0 8.4e-123 410.9 0.0 2.2 1 1 1 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 KEP63179.1 - 1.1e-49 168.5 0.0 2e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KEP63179.1 - 1.7e-26 92.4 0.0 4.7e-26 91.0 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEP63179.1 - 1e-23 83.3 0.0 5.8e-21 74.4 0.0 2.6 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KEP63179.1 - 7.7e-19 68.1 0.0 2e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KEP63179.1 - 1.6e-11 43.6 0.3 4.9e-11 42.1 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KEP63179.1 - 4.1e-11 42.2 0.0 0.00054 18.8 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KEP63179.1 - 3.1e-10 39.6 0.3 8.4e-10 38.2 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEP63179.1 - 1.3e-08 34.4 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KEP63179.1 - 4.1e-06 26.7 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KEP63179.1 - 0.16 11.4 0.0 0.47 9.9 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 KEP63179.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF3458 PF11940.3 KEP63180.1 - 1.2e-85 287.6 0.5 1.7e-85 287.0 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 KEP63180.1 - 3.3e-54 184.4 0.0 6.7e-54 183.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 KEP63180.1 - 1.9e-16 60.2 0.2 4.2e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KEP63180.1 - 0.032 14.2 0.1 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 M61 glycyl aminopeptidase DUF809 PF05663.6 KEP63182.1 - 2.2 8.1 0.2 9 6.2 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF809) 2OG-FeII_Oxy_3 PF13640.1 KEP63183.1 - 1.5e-06 28.6 0.0 3.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEP63183.1 - 3.6e-05 23.9 0.0 9.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEP63183.1 - 0.00029 20.4 0.0 0.00062 19.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0506 PF11703.3 KEP63184.1 - 0.8 9.7 7.6 0.12 12.3 2.0 2.0 2 0 0 2 2 2 0 UPF0506 DAHP_synth_2 PF01474.11 KEP63185.1 - 1.8e-177 590.1 0.0 2.2e-177 589.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DSPc PF00782.15 KEP63187.1 - 5.2e-05 22.8 0.3 9.6e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KEP63187.1 - 0.0011 19.2 0.0 0.011 15.9 0.0 2.4 3 0 0 3 3 3 1 Tyrosine phosphatase family PapD-like PF14874.1 KEP63188.1 - 0.01 15.7 3.7 2.9 7.8 0.0 4.1 4 0 0 4 4 4 0 Flagellar-associated PapD-like Pro_isomerase PF00160.16 KEP63189.1 - 3.7e-42 144.1 0.1 4.2e-42 143.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-CW PF07496.10 KEP63190.1 - 1.3e-26 92.0 25.0 1.9e-15 56.2 4.2 2.8 2 0 0 2 2 2 2 CW-type Zinc Finger PHD PF00628.24 KEP63190.1 - 0.025 14.2 6.2 0.28 10.8 1.3 2.8 2 0 0 2 2 2 0 PHD-finger NUDIX_2 PF13869.1 KEP63191.1 - 3.6e-48 163.3 0.0 4.8e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M48 PF01435.13 KEP63193.1 - 1.3e-49 168.7 0.0 2e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 UPF0104 PF03706.8 KEP63193.1 - 0.013 14.7 0.8 0.013 14.7 0.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) Acetyltransf_1 PF00583.19 KEP63194.1 - 2.9e-09 36.8 0.1 5.5e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEP63194.1 - 2.1e-06 27.7 0.1 3.7e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP63194.1 - 3.5e-05 23.4 0.1 8.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KEP63194.1 - 0.00022 21.0 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEP63194.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEP63194.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 KEP63194.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Apt1 PF10351.4 KEP63194.1 - 1.6 7.4 4.8 2.9 6.6 3.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain GRP PF07172.6 KEP63194.1 - 4.5 7.8 17.7 0.42 11.1 4.6 2.4 2 0 0 2 2 2 0 Glycine rich protein family 4HBT_3 PF13622.1 KEP63196.1 - 9.6 5.8 10.9 15 5.2 7.5 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily FtsJ PF01728.14 KEP63197.1 - 9.7e-52 175.5 0.0 1.3e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase NSP13 PF06460.7 KEP63197.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Coronavirus NSP13 Choline_transpo PF04515.7 KEP63198.1 - 3.1e-32 111.6 14.4 3.1e-32 111.6 10.0 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Telomere_reg-2 PF10193.4 KEP63199.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Telomere length regulation protein HEAT PF02985.17 KEP63200.1 - 2.2e-08 33.5 27.8 0.002 18.0 0.0 7.8 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 KEP63200.1 - 2.2e-06 27.8 14.9 0.0032 17.7 0.2 4.8 3 2 1 4 4 4 3 HEAT repeats Adaptin_N PF01602.15 KEP63200.1 - 0.0012 17.2 2.0 0.33 9.2 0.0 3.7 4 0 0 4 4 4 2 Adaptin N terminal region Glycoprotein_B PF00606.13 KEP63203.1 - 0.0021 16.1 0.1 0.0027 15.8 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B Dynactin_p22 PF07426.6 KEP63203.1 - 0.02 14.1 4.2 0.036 13.3 2.9 1.7 1 1 0 1 1 1 0 Dynactin subunit p22 DUF2340 PF10209.4 KEP63203.1 - 0.025 14.7 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) CorA PF01544.13 KEP63203.1 - 0.088 11.8 6.7 0.14 11.1 3.8 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Nucleic_acid_bd PF13820.1 KEP63203.1 - 0.22 11.1 2.5 0.28 10.7 0.5 1.9 2 0 0 2 2 2 0 Putative nucleic acid-binding region IncA PF04156.9 KEP63203.1 - 1.1 8.8 10.7 0.12 11.9 3.6 1.9 1 1 0 2 2 2 0 IncA protein BioY PF02632.9 KEP63204.1 - 0.043 13.4 0.3 0.043 13.4 0.2 2.1 2 0 0 2 2 2 0 BioY family DEAD PF00270.24 KEP63205.1 - 1.6e-31 109.0 0.0 5.5e-31 107.3 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP63205.1 - 1.8e-20 72.5 0.2 5.2e-20 71.0 0.2 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP63205.1 - 5.7e-05 23.0 0.0 0.00017 21.4 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Thr_synth_N PF14821.1 KEP63206.1 - 4.9e-20 71.3 0.1 1.6e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KEP63206.1 - 2e-12 46.9 0.0 7.3e-05 22.1 0.0 2.6 3 0 0 3 3 3 2 Pyridoxal-phosphate dependent enzyme DUF4229 PF14012.1 KEP63209.1 - 0.35 10.8 4.5 0.35 10.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Nse4_C PF08743.5 KEP63210.1 - 6.2e-05 22.9 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal RBFA PF02033.13 KEP63211.1 - 9e-08 32.0 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Ribosome-binding factor A Ubiq_cyt_C_chap PF03981.7 KEP63212.1 - 1e-18 67.5 0.5 2.5e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Trypan_glycop_C PF10659.4 KEP63212.1 - 0.14 12.5 7.6 0.38 11.0 5.3 1.7 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain DEAD PF00270.24 KEP63213.1 - 3.1e-40 137.4 1.1 2.7e-39 134.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP63213.1 - 3.8e-27 93.9 0.0 9.2e-27 92.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain eIF3_p135 PF12807.2 KEP63214.1 - 3.5e-12 46.5 0.0 1.7e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KEP63214.1 - 0.00039 20.2 4.2 0.26 11.2 0.2 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat DUF1682 PF07946.9 KEP63215.1 - 0.018 13.8 0.2 0.021 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_M18 PF02127.10 KEP63216.1 - 3.4e-142 473.9 0.0 4.1e-142 473.6 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KEP63216.1 - 9.1e-06 24.6 0.0 0.00015 20.6 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase ETF PF01012.16 KEP63216.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Fer4_18 PF13746.1 KEP63217.1 - 0.12 12.7 0.5 0.12 12.7 0.3 1.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain SSB PF00436.20 KEP63221.1 - 4e-28 97.3 0.1 7.4e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Fe-S_biosyn PF01521.15 KEP63222.1 - 2.8e-14 53.0 0.0 4.7e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2045 PF09741.4 KEP63223.1 - 0.12 11.4 0.3 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) Cation_ATPase_N PF00690.21 KEP63224.1 - 0.033 13.6 0.1 0.067 12.6 0.1 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus GST_N_3 PF13417.1 KEP63225.1 - 0.0078 16.4 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HCMV_UL139 PF12507.3 KEP63226.1 - 0.0046 17.1 0.2 0.047 13.8 0.0 2.5 2 0 0 2 2 2 1 Human Cytomegalovirus UL139 protein GlutR_dimer PF00745.15 KEP63227.1 - 0.0082 16.0 0.1 0.49 10.3 0.0 2.3 2 0 0 2 2 2 2 Glutamyl-tRNAGlu reductase, dimerisation domain Aminotran_4 PF01063.14 KEP63229.1 - 2.1e-13 50.2 0.0 3.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV DNA_primase_lrg PF04104.9 KEP63231.1 - 4.5e-60 203.1 0.0 6.2e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit MRP-S31 PF15433.1 KEP63232.1 - 3.1 7.1 7.9 6.4 6.1 5.5 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TraV PF09676.5 KEP63233.1 - 3 8.5 6.3 0.77 10.4 1.1 2.4 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Arm PF00514.18 KEP63234.1 - 6.7e-37 124.0 17.1 1.1e-06 28.1 0.0 9.6 10 0 0 10 10 10 7 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KEP63234.1 - 2.6e-18 64.3 5.6 2.2e-06 27.2 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KEP63234.1 - 1.2e-17 63.9 16.0 2.1e-06 27.9 0.1 5.3 2 2 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 KEP63234.1 - 2.7e-14 53.1 10.0 0.028 14.9 0.0 6.0 5 0 0 5 5 5 4 HEAT-like repeat Adaptin_N PF01602.15 KEP63234.1 - 4.3e-10 38.5 1.5 5.8e-05 21.6 0.1 3.5 2 2 0 3 3 3 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 KEP63234.1 - 3.9e-08 32.0 6.0 4e-05 22.0 0.2 3.6 1 1 2 4 4 4 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KEP63234.1 - 9.5e-06 25.5 0.2 0.0025 17.6 0.0 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.4 KEP63234.1 - 0.011 15.4 0.1 5.1 6.8 0.1 3.5 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.3 KEP63234.1 - 0.02 14.7 0.2 0.28 11.0 0.1 2.8 2 1 1 3 3 3 0 V-ATPase subunit H CLASP_N PF12348.3 KEP63234.1 - 0.023 14.0 5.4 0.28 10.5 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal EcoEI_R_C PF08463.5 KEP63234.1 - 0.028 14.2 0.1 0.096 12.5 0.0 2.1 2 1 0 2 2 2 0 EcoEI R protein C-terminal Vac14_Fab1_bd PF12755.2 KEP63234.1 - 0.056 13.8 0.1 0.63 10.4 0.0 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 KEP63234.1 - 0.47 11.0 15.1 20 6.0 0.0 6.6 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat PA28_alpha PF02251.13 KEP63235.1 - 0.095 12.8 0.2 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit SMC_N PF02463.14 KEP63236.1 - 1.7e-62 210.5 0.0 4e-62 209.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEP63236.1 - 2.9e-18 65.9 0.1 1.1e-17 64.0 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEP63236.1 - 2.3e-12 47.4 2.0 1.5e-05 25.1 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KEP63236.1 - 3.6e-07 30.7 27.8 3.6e-07 30.7 19.2 7.3 3 3 0 3 3 1 1 AAA domain Reo_sigmaC PF04582.7 KEP63236.1 - 5e-06 25.9 31.5 0.0003 20.1 0.9 5.5 3 2 2 5 5 5 3 Reovirus sigma C capsid protein AAA_13 PF13166.1 KEP63236.1 - 0.00036 19.1 22.9 0.00036 19.1 15.9 5.1 3 2 2 5 5 5 3 AAA domain Spc7 PF08317.6 KEP63236.1 - 0.00045 18.9 19.4 0.00045 18.9 13.5 6.8 3 2 3 7 7 7 2 Spc7 kinetochore protein ABC_tran PF00005.22 KEP63236.1 - 0.0026 18.0 0.2 0.0026 18.0 0.1 6.0 3 2 1 5 5 4 2 ABC transporter Tup_N PF08581.5 KEP63236.1 - 0.0037 17.4 6.2 0.0037 17.4 4.3 9.2 6 2 3 10 10 8 2 Tup N-terminal AAA_29 PF13555.1 KEP63236.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 KEP63236.1 - 0.0066 16.2 23.9 0.0066 16.2 16.6 7.6 5 3 3 8 8 8 2 Tropomyosin like AAA_15 PF13175.1 KEP63236.1 - 0.02 13.9 0.0 0.02 13.9 0.0 3.7 3 1 0 3 3 2 0 AAA ATPase domain DUF869 PF05911.6 KEP63236.1 - 0.83 7.8 102.7 0.76 7.9 14.6 4.2 2 2 2 4 4 4 0 Plant protein of unknown function (DUF869) Surfac_D-trimer PF09006.6 KEP63236.1 - 1.2 8.9 21.1 0.51 10.1 1.1 6.1 5 1 1 6 6 5 0 Lung surfactant protein D coiled-coil trimerisation GAS PF13851.1 KEP63236.1 - 1.8 7.7 122.2 0.22 10.7 15.7 7.8 2 2 6 8 8 8 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 KEP63236.1 - 3.6 7.4 41.0 0.013 15.3 2.4 6.6 2 2 5 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_gyraseB PF00204.20 KEP63238.1 - 1.3e-32 112.3 0.0 1.4e-21 76.5 0.0 2.7 3 0 0 3 3 3 2 DNA gyrase B Toprim PF01751.17 KEP63238.1 - 1.4e-24 85.9 0.0 5.3e-24 84.1 0.0 2.1 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB_C PF00986.16 KEP63238.1 - 7.3e-22 76.8 0.0 1.4e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.21 KEP63238.1 - 8.9e-13 47.9 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.1 KEP63238.1 - 0.0025 17.8 0.0 0.083 12.9 0.0 2.8 1 1 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.1 KEP63238.1 - 0.023 14.3 0.0 0.063 12.9 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SDA1 PF05285.7 KEP63239.1 - 2.1 7.5 32.7 2.6 7.2 22.7 1.1 1 0 0 1 1 1 0 SDA1 Herpes_DNAp_acc PF04929.7 KEP63239.1 - 3.5 6.4 11.3 3.8 6.3 7.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CENP-T PF15511.1 KEP63239.1 - 7.6 5.6 20.1 9.6 5.3 13.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4242 PF14026.1 KEP63240.1 - 0.071 13.2 0.7 0.7 10.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) SLX9 PF15341.1 KEP63241.1 - 7.9e-17 61.8 0.4 7.9e-17 61.8 0.2 2.0 3 0 0 3 3 3 1 Ribosome biogenesis protein SLX9 Elf1 PF05129.8 KEP63243.1 - 3.2e-27 94.0 0.2 5e-27 93.4 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like SpoIIIAH PF12685.2 KEP63243.1 - 0.27 10.7 5.9 0.38 10.2 4.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Kinocilin PF15033.1 KEP63243.1 - 0.63 9.5 2.8 0.45 10.0 0.5 1.8 1 1 1 2 2 2 0 Kinocilin protein Glyco_transf_20 PF00982.16 KEP63244.1 - 2.5e-122 408.7 0.0 4.2e-122 408.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KEP63244.1 - 2.1e-56 190.5 0.0 1e-54 184.9 0.0 2.3 2 0 0 2 2 2 1 Trehalose-phosphatase CBM_20 PF00686.14 KEP63244.1 - 1.5e-16 59.7 0.0 3e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Hydrolase_3 PF08282.7 KEP63244.1 - 0.00046 19.8 0.0 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cupin_1 PF00190.17 KEP63246.1 - 0.003 17.0 0.7 0.0049 16.3 0.5 1.5 1 1 0 1 1 1 1 Cupin EF-hand_7 PF13499.1 KEP63248.1 - 2.5e-20 72.3 4.0 6.7e-12 45.3 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP63248.1 - 2.6e-15 54.8 5.5 2.4e-07 30.0 0.4 4.2 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KEP63248.1 - 8.6e-15 52.8 9.2 4.3e-08 31.9 0.5 4.9 5 1 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 KEP63248.1 - 4.9e-09 35.6 5.2 0.00045 19.7 0.4 4.2 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.1 KEP63248.1 - 5.7e-09 35.7 0.0 6.4e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KEP63248.1 - 1.6e-08 33.5 2.8 7.2e-05 21.9 1.4 2.8 2 0 0 2 2 2 2 EF hand UPF0154 PF03672.8 KEP63248.1 - 0.00035 20.1 0.0 0.32 10.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 KEP63248.1 - 0.019 14.6 1.1 8 6.2 0.1 2.7 2 1 1 3 3 3 0 Tellurite resistance protein TerB tRNA-synt_1c_C PF03950.13 KEP63248.1 - 0.02 14.5 0.0 0.026 14.1 0.0 1.3 1 1 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DUF2789 PF10982.3 KEP63248.1 - 0.055 13.4 1.3 1 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) Lin-8 PF03353.10 KEP63249.1 - 6.9 5.8 6.4 7.8 5.6 4.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4200 PF13863.1 KEP63250.1 - 5.3e-15 55.4 11.5 5.3e-15 55.4 8.0 4.4 2 2 1 3 3 3 1 Domain of unknown function (DUF4200) SOG2 PF10428.4 KEP63250.1 - 0.013 14.1 1.2 0.013 14.1 0.8 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Fib_alpha PF08702.5 KEP63250.1 - 0.022 14.8 3.2 0.022 14.8 2.2 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DICT PF10069.4 KEP63250.1 - 0.087 12.3 0.5 0.25 10.8 0.2 2.0 2 0 0 2 2 2 0 Sensory domain found in DIguanylate Cyclases & Two-component systems PHP PF02811.14 KEP63250.1 - 1.6 8.5 4.6 4.3 7.0 3.1 2.0 1 1 0 1 1 1 0 PHP domain DUF4351 PF14261.1 KEP63250.1 - 6.1 6.7 11.1 1.2 9.0 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4351) DUF1835 PF08874.5 KEP63250.1 - 9.3 6.2 10.2 10 6.0 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1835) Metallophos PF00149.23 KEP63251.1 - 1.2e-09 37.8 1.7 1.2e-08 34.5 1.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEP63251.1 - 0.0063 16.3 0.0 0.026 14.3 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acyltransferase PF01553.16 KEP63253.1 - 9.5e-21 73.6 0.0 2.3e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase RNA_pol_Rpb2_6 PF00562.23 KEP63254.1 - 1.7e-114 382.5 0.0 2.3e-114 382.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEP63254.1 - 4.3e-25 87.8 0.0 7.1e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KEP63254.1 - 3.6e-22 77.8 0.0 7e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 KEP63254.1 - 7.2e-18 64.6 0.0 1.4e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 KEP63254.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain Reo_sigmaC PF04582.7 KEP63255.1 - 0.2 10.8 10.0 0.11 11.6 1.0 3.0 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PPTA PF01239.17 KEP63256.1 - 7.1e-24 82.1 8.6 3.6e-08 32.4 0.8 4.6 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat MIP-T3 PF10243.4 KEP63257.1 - 10 4.4 22.2 12 4.1 15.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cpn60_TCP1 PF00118.19 KEP63258.1 - 1.2e-142 475.9 0.1 1.5e-142 475.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1515 PF07439.6 KEP63259.1 - 0.35 10.6 3.2 0.92 9.3 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) V_ATPase_I PF01496.14 KEP63259.1 - 0.98 7.1 4.0 1.8 6.3 2.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apc1 PF12859.2 KEP63259.1 - 4.8 7.4 6.6 1.1 9.5 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 1 EF-hand_6 PF13405.1 KEP63261.1 - 0.0082 15.9 0.0 0.054 13.3 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain WD40 PF00400.27 KEP63262.1 - 2.4e-08 33.5 2.1 0.25 11.2 0.0 5.9 5 2 0 5 5 5 3 WD domain, G-beta repeat TruB_C PF09142.6 KEP63262.1 - 0.073 12.7 0.0 13 5.4 0.0 2.7 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal DUF2700 PF10912.3 KEP63262.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) YbfN PF13982.1 KEP63265.1 - 0.0037 17.3 1.0 0.021 14.9 0.0 2.0 1 1 1 2 2 2 1 YbfN-like lipoprotein GAS PF13851.1 KEP63265.1 - 0.019 14.1 8.6 0.022 13.9 5.9 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 KEP63265.1 - 0.029 14.3 5.3 0.039 13.9 3.7 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 KEP63265.1 - 0.035 14.0 9.4 0.042 13.8 5.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4559 PF15112.1 KEP63265.1 - 0.067 12.3 4.1 0.074 12.2 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF2400 PF09674.5 KEP63265.1 - 0.069 12.8 0.8 0.077 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) IncA PF04156.9 KEP63265.1 - 0.07 12.7 8.4 0.11 12.1 5.9 1.3 1 1 0 1 1 1 0 IncA protein Caldesmon PF02029.10 KEP63265.1 - 0.073 11.4 5.0 0.077 11.4 3.4 1.0 1 0 0 1 1 1 0 Caldesmon DUF2408 PF10303.4 KEP63265.1 - 0.081 13.0 3.5 0.11 12.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) APG6 PF04111.7 KEP63265.1 - 0.088 11.8 6.7 0.099 11.6 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 KEP63265.1 - 0.1 12.5 4.6 0.12 12.2 3.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Hom_end PF05204.9 KEP63265.1 - 0.12 12.3 0.7 0.14 12.1 0.5 1.1 1 0 0 1 1 1 0 Homing endonuclease DUF4220 PF13968.1 KEP63265.1 - 0.17 10.9 1.4 0.18 10.8 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) V_ATPase_I PF01496.14 KEP63265.1 - 0.37 8.5 3.6 0.41 8.4 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 KEP63265.1 - 0.88 8.4 7.4 1.1 8.1 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rho_Binding PF08912.6 KEP63265.1 - 1.7 8.9 8.6 0.86 9.9 4.1 1.9 1 1 1 2 2 2 0 Rho Binding FoP_duplication PF13865.1 KEP63266.1 - 9.3e-17 61.2 15.2 9.3e-17 61.2 10.6 4.0 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 TFCD_C PF12612.3 KEP63267.1 - 6e-06 25.8 1.3 0.038 13.4 0.0 4.5 4 0 0 4 4 4 2 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 KEP63267.1 - 0.037 14.5 0.1 0.037 14.5 0.1 10.0 10 1 1 11 11 11 0 HEAT-like repeat DisA_N PF02457.11 KEP63267.1 - 0.17 11.0 0.0 0.49 9.5 0.0 1.7 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Vac14_Fab1_bd PF12755.2 KEP63267.1 - 0.18 12.1 0.0 1.1 9.6 0.0 2.4 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region TMEM247 PF15444.1 KEP63267.1 - 8.8 6.0 7.0 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 247 DUF1510 PF07423.6 KEP63268.1 - 9.6 5.5 36.4 0.54 9.5 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) CENP-U PF13097.1 KEP63269.1 - 0.71 9.7 9.9 1.7 8.5 6.9 1.6 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit WD40 PF00400.27 KEP63270.1 - 7.1e-12 44.7 4.7 0.1 12.5 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat TIP49 PF06068.8 KEP63271.1 - 3.4e-180 598.9 2.3 3.9e-180 598.7 1.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KEP63271.1 - 8.3e-12 45.4 0.2 1.3e-08 35.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEP63271.1 - 9.7e-11 41.1 2.5 2.1e-06 26.9 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEP63271.1 - 8.2e-08 32.4 0.1 0.017 15.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEP63271.1 - 4.5e-07 30.0 0.0 0.0043 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KEP63271.1 - 8.1e-06 25.6 0.1 0.0016 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEP63271.1 - 7.9e-05 22.3 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KEP63271.1 - 0.00015 21.0 0.2 0.0064 15.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KEP63271.1 - 0.00018 21.8 0.1 0.0007 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEP63271.1 - 0.00038 21.2 0.0 0.0011 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEP63271.1 - 0.00046 19.6 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 KEP63271.1 - 0.00058 19.3 0.2 0.68 9.3 0.0 2.9 2 1 1 3 3 3 2 Sigma-54 interaction domain AAA_14 PF13173.1 KEP63271.1 - 0.00069 19.5 0.0 0.91 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEP63271.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEP63271.1 - 0.0021 18.0 0.0 0.0054 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 KEP63271.1 - 0.0025 16.9 0.1 0.0069 15.5 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.1 KEP63271.1 - 0.0057 17.0 0.0 0.0093 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP63271.1 - 0.0062 16.4 0.0 0.019 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 KEP63271.1 - 0.0099 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DUF2075 PF09848.4 KEP63271.1 - 0.014 14.4 0.0 0.028 13.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KEP63271.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEP63271.1 - 0.038 13.2 0.1 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATP-synt_ab PF00006.20 KEP63271.1 - 0.04 13.3 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.1 KEP63271.1 - 0.044 13.8 0.0 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KEP63271.1 - 0.044 12.6 0.1 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 KEP63271.1 - 0.044 13.9 0.0 0.098 12.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.10 KEP63271.1 - 0.071 12.9 0.5 0.59 9.9 0.1 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 KEP63271.1 - 0.089 12.4 0.1 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KEP63271.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 KEP63272.1 - 2.4e-21 75.9 0.8 2.6e-21 75.7 0.6 1.0 1 0 0 1 1 1 1 TIP49 C-terminus DUF3903 PF13043.1 KEP63272.1 - 0.076 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) DUF3841 PF12952.2 KEP63273.1 - 0.039 13.4 0.0 0.039 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3841) Syntaxin_2 PF14523.1 KEP63274.1 - 0.34 10.9 6.3 1.2 9.2 0.4 3.0 2 1 1 3 3 3 0 Syntaxin-like protein PRT_C PF08372.5 KEP63276.1 - 0.095 12.1 0.2 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.6 KEP63276.1 - 0.15 10.7 0.7 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin IgaA PF07095.6 KEP63276.1 - 5.9 4.5 1.1 8.8 3.9 0.8 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Nop14 PF04147.7 KEP63279.1 - 9.8 3.9 11.3 9.4 4.0 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KEP63279.1 - 9.9 5.3 10.9 10 5.2 7.5 1.1 1 0 0 1 1 1 0 SDA1 MFS_1 PF07690.11 KEP63283.1 - 4.1e-12 45.4 41.9 2.3e-09 36.4 11.5 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEP63283.1 - 0.00025 19.6 1.0 0.00025 19.6 0.7 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein Vps53_N PF04100.7 KEP63284.1 - 2.8e-57 194.2 3.0 1.6e-26 93.0 0.0 4.1 2 2 0 2 2 2 2 Vps53-like, N-terminal CENP-B_dimeris PF09026.5 KEP63284.1 - 0.0051 17.0 0.7 0.016 15.4 0.5 1.8 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 KEP63284.1 - 0.033 13.8 4.8 0.19 11.2 0.6 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 KEP63284.1 - 0.25 11.6 1.8 0.58 10.5 1.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3573 PF12097.3 KEP63284.1 - 0.37 9.3 0.6 0.59 8.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) BSP_II PF05432.6 KEP63284.1 - 1.1 8.5 8.3 1.9 7.7 5.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MTBP_C PF14920.1 KEP63284.1 - 3.5 7.0 17.4 4.2 6.7 10.0 2.4 2 1 0 2 2 2 0 MDM2-binding AMP-binding PF00501.23 KEP63286.1 - 4.2e-80 269.1 0.0 1e-78 264.5 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme DDHD PF02862.12 KEP63288.1 - 0.41 10.3 17.9 0.53 10.0 12.4 1.1 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 KEP63288.1 - 0.67 7.7 43.7 0.75 7.6 30.3 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 KEP63288.1 - 0.89 7.8 44.6 1 7.6 30.9 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF4045 PF13254.1 KEP63288.1 - 1.1 8.4 15.2 1.2 8.3 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1510 PF07423.6 KEP63288.1 - 2.9 7.2 36.2 3.3 7.0 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-T PF15511.1 KEP63288.1 - 3.7 6.6 26.1 4 6.5 18.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 KEP63288.1 - 4 6.8 36.0 4.8 6.5 24.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SprA-related PF12118.3 KEP63288.1 - 5.5 6.2 23.8 6.3 6.0 16.5 1.0 1 0 0 1 1 1 0 SprA-related family CDC45 PF02724.9 KEP63288.1 - 7.8 4.3 31.6 9 4.1 21.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 KEP63288.1 - 9.3 6.0 28.5 11 5.7 19.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CRAL_TRIO PF00650.15 KEP63289.1 - 0.0063 16.0 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Ribosomal_L17 PF01196.14 KEP63290.1 - 7.4e-19 68.1 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 R3H PF01424.17 KEP63290.1 - 0.084 12.5 1.4 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 R3H domain Coa1 PF08695.5 KEP63291.1 - 0.00047 19.6 0.0 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 FimP PF09766.4 KEP63291.1 - 4.1 6.3 9.0 8.2 5.3 0.0 2.2 2 0 0 2 2 2 0 Fms-interacting protein MORN PF02493.15 KEP63292.1 - 2.8e-45 149.3 46.7 7.5e-07 28.5 0.5 10.2 10 0 0 10 10 10 9 MORN repeat BsuPI PF12690.2 KEP63292.1 - 0.1 12.3 0.1 0.4 10.4 0.0 2.1 1 0 0 1 1 1 0 Intracellular proteinase inhibitor LSM PF01423.17 KEP63293.1 - 4.2e-13 48.6 0.0 5.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain RNA_pol_I_A49 PF06870.7 KEP63294.1 - 0.054 12.0 0.2 0.23 9.9 0.0 1.9 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor DivIC PF04977.10 KEP63295.1 - 0.23 10.9 1.3 0.54 9.7 0.9 1.6 1 0 0 1 1 1 0 Septum formation initiator OmpH PF03938.9 KEP63295.1 - 4.3 7.2 13.3 0.18 11.7 4.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Kinesin PF00225.18 KEP63296.1 - 7.3e-96 320.7 0.0 1.2e-94 316.7 0.0 2.6 1 1 0 1 1 1 1 Kinesin motor domain Rsa3 PF14615.1 KEP63296.1 - 0.11 11.7 0.1 0.28 10.5 0.1 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Phos_pyr_kin PF08543.7 KEP63299.1 - 2.2e-06 27.0 0.0 0.00028 20.1 0.0 2.3 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase PfkB PF00294.19 KEP63299.1 - 0.0064 15.6 0.0 1.7 7.6 0.0 2.9 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Carb_anhydrase PF00194.16 KEP63300.1 - 1.2e-12 47.3 1.0 6.3e-10 38.4 0.1 3.0 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase His_Phos_1 PF00300.17 KEP63301.1 - 1.7e-42 145.1 0.0 2.3e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RIB43A PF05914.7 KEP63302.1 - 6.9e-09 34.8 3.6 6.9e-09 34.8 2.5 1.0 1 0 0 1 1 1 1 RIB43A INCENP_ARK-bind PF03941.10 KEP63302.1 - 0.0046 16.7 1.2 0.006 16.3 0.8 1.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region eIF3_subunit PF08597.5 KEP63302.1 - 0.038 13.5 0.4 0.038 13.5 0.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit START PF01852.14 KEP63303.1 - 9.2e-08 31.6 0.0 1.9e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 START domain tRNA_bind PF01588.15 KEP63305.1 - 2.9e-27 94.3 0.0 4.9e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 KEP63305.1 - 1e-05 25.3 0.1 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEP63305.1 - 3.1e-05 23.7 0.1 6.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEP63305.1 - 0.00021 21.7 0.0 0.00042 20.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TRM13 PF05206.9 KEP63306.1 - 5.4e-34 117.5 2.6 5.2e-20 71.7 0.2 4.0 2 2 1 3 3 3 3 Methyltransferase TRM13 zf-U11-48K PF05253.7 KEP63306.1 - 0.00065 19.3 0.5 0.0014 18.3 0.4 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 KEP63306.1 - 0.018 14.7 7.0 3.5 7.2 0.0 3.6 3 0 0 3 3 3 0 Methyltransferase domain ubiquitin PF00240.18 KEP63307.1 - 3.6e-24 83.9 0.5 4.2e-24 83.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEP63307.1 - 7.4e-13 47.9 0.4 8.3e-13 47.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEP63307.1 - 0.018 15.2 0.1 0.04 14.1 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KEP63307.1 - 0.02 14.8 0.1 0.047 13.5 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CKS PF01111.14 KEP63308.1 - 1.2e-12 47.4 2.3 2e-12 46.7 1.6 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1462 PF07315.6 KEP63308.1 - 0.3 11.0 1.6 0.43 10.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) GLTP PF08718.6 KEP63309.1 - 1.1e-29 103.3 0.0 1.4e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Spore_YtfJ PF09579.5 KEP63309.1 - 0.032 14.0 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) AAA_16 PF13191.1 KEP63310.1 - 0.00051 20.0 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KEP63310.1 - 0.0027 16.8 0.0 0.007 15.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KEP63310.1 - 0.022 14.5 0.0 0.09 12.5 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 KEP63310.1 - 0.048 13.5 0.0 0.2 11.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEP63310.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KEP63310.1 - 0.083 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KEP63310.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1561 PF07598.6 KEP63310.1 - 0.36 8.7 0.1 0.54 8.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) MORN PF02493.15 KEP63313.1 - 3e-21 73.8 45.7 3.6e-05 23.2 0.0 10.8 11 0 0 11 11 11 8 MORN repeat Cadherin-like PF12733.2 KEP63313.1 - 0.00037 20.7 0.0 0.52 10.6 0.0 3.7 4 0 0 4 4 4 1 Cadherin-like beta sandwich domain MSP1_C PF07462.6 KEP63313.1 - 5.1 5.3 0.0 10 4.3 0.0 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ribosomal_S10 PF00338.17 KEP63314.1 - 1.9e-31 107.7 0.1 3.1e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e TPR_11 PF13414.1 KEP63316.1 - 8.9e-10 38.0 1.9 2.6e-05 23.7 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEP63316.1 - 5.1e-05 22.8 6.5 0.034 14.0 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP63316.1 - 0.0003 20.6 4.0 0.18 11.7 0.2 2.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP63316.1 - 0.00078 18.9 0.2 0.89 9.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP63316.1 - 0.0047 16.5 0.5 0.24 11.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP63316.1 - 0.073 13.7 3.0 13 6.6 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP63316.1 - 0.15 12.7 5.6 2.2 9.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KEP63316.1 - 0.22 11.6 1.7 2.6 8.2 0.2 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Coprogen_oxidas PF01218.13 KEP63317.1 - 1.2e-111 371.9 0.5 1.2e-110 368.6 0.4 1.9 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Dynein_light PF01221.13 KEP63318.1 - 2.4e-44 149.2 0.5 2.6e-44 149.0 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 KEP63318.1 - 0.12 11.9 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 28 Ribosomal_S18 PF01084.15 KEP63319.1 - 4.3e-15 55.3 0.0 1.1e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S18 PAN_4 PF14295.1 KEP63320.1 - 1.2e-05 24.8 0.2 2.8e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 KEP63320.1 - 2.4e-05 24.0 0.4 4.6e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 KEP63321.1 - 2.6e-12 46.2 4.2 4e-06 26.4 0.1 2.4 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.21 KEP63321.1 - 9.7e-12 44.4 3.9 1.4e-05 24.7 0.3 2.4 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.7 KEP63321.1 - 0.071 12.7 1.2 6.5 6.4 0.1 2.5 2 0 0 2 2 2 0 PAN-like domain Inositol_P PF00459.20 KEP63322.1 - 1.6e-71 240.8 0.1 2.1e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Pkinase PF00069.20 KEP63323.1 - 2.9e-17 62.6 0.0 1.8e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63323.1 - 2.5e-07 30.0 0.0 7.9e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Ocnus PF05005.10 KEP63324.1 - 1.5e-23 82.7 0.1 2.8e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) CPW_WPC PF09717.5 KEP63325.1 - 0.079 13.5 5.1 0.17 12.4 0.0 3.5 3 1 0 3 3 3 0 Plasmodium falciparum domain of unknown function (CPW_WPC) RHINO PF15319.1 KEP63326.1 - 0.0048 16.7 0.5 0.0048 16.7 0.3 1.9 1 1 0 2 2 2 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein Tropomyosin PF00261.15 KEP63326.1 - 0.01 14.9 18.4 0.039 13.0 7.5 2.2 2 0 0 2 2 2 2 Tropomyosin DUF2570 PF10828.3 KEP63326.1 - 0.46 10.1 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DUF814 PF05670.8 KEP63327.1 - 3.2e-17 62.1 0.0 6e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Sedlin_N PF04628.8 KEP63328.1 - 2.3e-37 127.7 0.0 2.7e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KEP63328.1 - 2.4e-05 24.0 0.0 8.2e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Sybindin-like family LRV_FeS PF05484.6 KEP63328.1 - 0.061 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 LRV protein FeS4 cluster His_Phos_1 PF00300.17 KEP63329.1 - 2.3e-16 60.2 0.0 4.9e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HAD PF12710.2 KEP63330.1 - 1.2e-16 61.4 0.2 9.4e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEP63330.1 - 2.5e-10 41.1 12.5 2e-09 38.1 0.3 4.0 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KEP63330.1 - 2.1e-07 30.3 0.0 5.2e-06 25.7 0.0 2.8 3 1 0 3 3 3 1 Putative Phosphatase Hydrolase_3 PF08282.7 KEP63330.1 - 4.3e-07 29.7 0.2 1.1e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.1 KEP63330.1 - 0.00037 20.1 0.2 3.6 7.3 0.0 4.6 5 0 0 5 5 5 2 ACT domain HAD_2 PF13419.1 KEP63330.1 - 0.0019 18.4 0.0 0.0058 16.8 0.0 1.9 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 KEP63330.1 - 0.54 9.1 0.1 0.98 8.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) FliE PF02049.13 KEP63331.1 - 0.041 13.9 1.3 0.17 11.9 0.3 2.5 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE DUF2372 PF10178.4 KEP63332.1 - 4.2e-06 26.8 0.0 8.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) eIF2A PF08662.6 KEP63333.1 - 2.1e-30 105.8 5.2 1.2e-24 87.0 0.5 3.1 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KEP63333.1 - 3.7e-07 29.6 0.0 1.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP63333.1 - 0.0025 17.6 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KEP63333.1 - 0.0064 16.3 0.0 53 3.9 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat RRM_6 PF14259.1 KEP63333.1 - 0.011 15.6 0.0 0.038 13.9 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Dabb PF07876.7 KEP63334.1 - 1.8e-19 69.9 0.3 2e-19 69.8 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Metallophos PF00149.23 KEP63335.1 - 2.7e-10 39.9 3.0 7.2e-10 38.6 2.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEP63335.1 - 4.5e-08 33.0 0.0 6.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Thioredoxin_7 PF13899.1 KEP63335.1 - 0.13 12.3 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like Glyco_transf_5 PF08323.6 KEP63336.1 - 1.6e-33 116.2 0.0 2.6e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 KEP63336.1 - 4e-14 52.3 0.0 6.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 KEP63336.1 - 1.3 8.3 0.0 6.3 6.0 0.0 1.9 2 0 0 2 2 2 0 Alpha amylase, catalytic domain DUF4203 PF13886.1 KEP63336.1 - 1.4 8.3 0.0 2.5 7.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Guanylate_cyc PF00211.15 KEP63336.1 - 2 7.7 0.6 7.9 5.7 0.0 2.0 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain DUF2827 PF10933.3 KEP63336.1 - 2.7 6.3 0.0 4.1 5.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) ISN1 PF06437.6 KEP63337.1 - 2e-83 280.4 0.0 2.8e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase LRR_4 PF12799.2 KEP63339.1 - 9e-18 63.4 3.9 2.6e-08 33.3 0.1 4.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP63339.1 - 8.4e-15 54.2 9.4 5.5e-07 29.2 3.6 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 KEP63339.1 - 2.7e-08 32.7 3.5 7 7.1 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 KEP63339.1 - 6.5e-06 25.6 3.2 8 6.8 0.0 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 KEP63339.1 - 0.0014 18.4 7.9 20 5.9 0.1 6.3 7 0 0 7 7 7 1 Leucine rich repeat DUF2920 PF11144.3 KEP63339.1 - 0.38 9.7 0.0 0.63 8.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) RCC1 PF00415.13 KEP63340.1 - 0.007 16.5 0.4 2.2 8.5 0.0 3.2 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP63340.1 - 0.22 11.1 1.0 7 6.4 0.1 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.18 KEP63342.1 - 1.5e-70 237.3 1.2 1.5e-70 237.3 0.8 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP63342.1 - 3.2e-15 55.7 0.1 8.6e-15 54.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP63342.1 - 0.0075 16.1 0.0 0.035 13.9 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KEP63342.1 - 0.025 13.3 0.0 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Gpi1 PF05024.10 KEP63343.1 - 3.7e-30 105.0 3.8 1.8e-21 76.6 0.6 2.3 2 0 0 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) Dus PF01207.12 KEP63344.1 - 4.2e-50 170.3 0.0 7.4e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) RCC1 PF00415.13 KEP63345.1 - 3.1e-26 91.3 7.0 1.9e-08 34.3 0.1 6.5 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP63345.1 - 1.2e-22 78.9 19.8 7.7e-06 25.3 0.6 5.9 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat WEMBL PF05701.6 KEP63345.1 - 0.46 8.8 136.8 0.22 9.9 75.2 2.7 1 1 2 3 3 3 0 Weak chloroplast movement under blue light UQ_con PF00179.21 KEP63346.1 - 1.1e-36 125.2 0.0 1.4e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2246 PF10229.4 KEP63346.1 - 0.14 11.4 0.2 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) ER PF01133.12 KEP63347.1 - 1.3e-42 143.6 0.9 1.5e-42 143.5 0.6 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_S24 PF00717.18 KEP63348.1 - 1.8e-11 43.4 0.1 3.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like ParA PF10609.4 KEP63349.1 - 8.8e-31 105.6 0.2 2.9e-30 103.9 0.1 1.8 1 1 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KEP63349.1 - 1.4e-16 60.5 0.0 1.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KEP63349.1 - 9.3e-05 21.6 0.1 0.00088 18.4 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase NB-ARC PF00931.17 KEP63349.1 - 0.00036 19.4 0.1 0.00054 18.9 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF258 PF03193.11 KEP63349.1 - 0.0012 18.0 0.1 0.0024 17.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_26 PF13500.1 KEP63349.1 - 0.0015 18.1 0.2 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KEP63349.1 - 0.0031 16.6 0.0 0.0086 15.1 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 KEP63349.1 - 0.0054 16.6 0.0 0.073 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEP63349.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KEP63349.1 - 0.0068 15.2 0.1 0.01 14.6 0.1 1.2 1 0 0 1 1 1 1 ArgK protein IstB_IS21 PF01695.12 KEP63349.1 - 0.026 13.9 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 KEP63349.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PIF1 PF05970.9 KEP63349.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase Zeta_toxin PF06414.7 KEP63349.1 - 0.16 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin Abi PF02517.11 KEP63351.1 - 2.2e-23 82.2 0.0 4.3e-22 78.0 0.0 2.6 2 2 0 2 2 2 1 CAAX protease self-immunity Proteasome PF00227.21 KEP63352.1 - 3.5e-28 98.2 0.0 1e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 Proteasome subunit DUF3457 PF11939.3 KEP63352.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3457) OKR_DC_1 PF01276.15 KEP63353.1 - 6.6e-72 242.3 0.0 2.4e-50 171.2 0.0 2.2 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.10 KEP63353.1 - 0.0023 18.0 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Beta_elim_lyase PF01212.16 KEP63353.1 - 0.022 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KEP63353.1 - 0.035 13.0 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II DNA_pol_E_B PF04042.11 KEP63354.1 - 2.8e-23 82.2 0.0 4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B IFT57 PF10498.4 KEP63355.1 - 0.04 12.6 1.5 0.051 12.3 1.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SbcD_C PF12320.3 KEP63355.1 - 0.041 13.9 0.6 1.6 8.7 0.1 2.4 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Spore_III_AB PF09548.5 KEP63355.1 - 0.073 12.8 0.9 0.099 12.3 0.2 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) FlxA PF14282.1 KEP63355.1 - 0.073 13.0 0.2 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 FlxA-like protein Cep57_CLD_2 PF14197.1 KEP63355.1 - 0.074 13.0 2.7 0.15 12.0 1.8 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Tox-ODYAM1 PF15642.1 KEP63355.1 - 0.076 11.6 2.2 0.097 11.3 1.6 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF3123 PF11321.3 KEP63355.1 - 0.13 12.5 0.3 0.13 12.5 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) Atg14 PF10186.4 KEP63355.1 - 0.6 9.0 4.4 0.8 8.5 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Packaging_FI PF14000.1 KEP63355.1 - 0.74 10.0 4.8 1.1 9.5 0.8 2.2 1 1 1 2 2 2 0 DNA packaging protein FI HAUS6_N PF14661.1 KEP63355.1 - 0.84 8.9 6.3 1.2 8.3 4.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sugar_transport PF06800.7 KEP63356.1 - 1.7e-09 37.1 13.1 0.00011 21.3 2.0 2.3 2 0 0 2 2 2 2 Sugar transport protein DUF1632 PF07857.7 KEP63356.1 - 5.3e-05 22.5 7.2 0.0019 17.5 0.5 2.5 1 1 1 2 2 2 2 CEO family (DUF1632) HECT PF00632.20 KEP63357.1 - 3.2e-43 148.0 0.0 5.3e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4222 PF13973.1 KEP63358.1 - 0.14 11.5 0.5 7.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) SRP54 PF00448.17 KEP63359.1 - 7.6e-54 182.1 0.3 2.2e-53 180.6 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 KEP63359.1 - 1.1e-23 84.0 3.7 2.4e-22 79.6 0.1 2.0 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 KEP63359.1 - 0.00036 20.0 0.5 0.0022 17.4 0.4 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 KEP63359.1 - 0.00044 19.8 0.1 0.00087 18.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP63359.1 - 0.00046 20.2 0.1 0.0063 16.5 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain ArgK PF03308.11 KEP63359.1 - 0.00048 18.9 0.0 0.001 17.9 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 KEP63359.1 - 0.00078 19.5 0.0 0.0053 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54_N PF02881.14 KEP63359.1 - 0.0092 16.0 1.6 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain NTPase_1 PF03266.10 KEP63359.1 - 0.015 15.0 0.0 8.1 6.1 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 KEP63359.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KEP63359.1 - 0.038 13.7 0.1 0.61 9.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 KEP63359.1 - 0.069 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF4632 PF15451.1 KEP63359.1 - 6.6 6.7 7.7 1.9 8.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) tRNA-synt_His PF13393.1 KEP63361.1 - 1.2e-44 152.6 0.0 2e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KEP63361.1 - 6.3e-15 55.1 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEP63361.1 - 2.4e-10 40.1 0.0 5.4e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Lyase_aromatic PF00221.14 KEP63361.1 - 3e-08 32.5 0.4 0.002 16.6 0.1 2.2 2 0 0 2 2 2 2 Aromatic amino acid lyase tRNA-synt_2 PF00152.15 KEP63361.1 - 0.0011 17.8 0.1 0.0051 15.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 KEP63361.1 - 0.0097 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.15 KEP63361.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) bPH_5 PF10882.3 KEP63364.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain Nitr_red_bet_C PF14711.1 KEP63364.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal AIRS_C PF02769.17 KEP63365.1 - 9e-18 64.7 0.0 5.6e-17 62.1 0.0 2.3 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KEP63365.1 - 1.4e-06 28.4 0.1 5.6e-06 26.5 0.0 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Pyr_redox_2 PF07992.9 KEP63365.1 - 0.0018 18.2 0.0 0.035 13.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEP63365.1 - 0.0027 18.0 0.1 0.026 14.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Clat_adaptor_s PF01217.15 KEP63366.1 - 8.5e-09 35.2 0.1 1.2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ecm29 PF13001.2 KEP63367.1 - 5.4e-18 64.7 0.0 6.6e-17 61.1 0.0 2.4 1 1 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 KEP63367.1 - 0.0021 17.9 7.5 0.39 10.9 0.1 6.4 5 0 0 5 5 5 1 HEAT repeat DTW PF03942.10 KEP63368.1 - 1.3e-13 50.6 0.1 2.2e-05 23.7 0.0 3.3 3 0 0 3 3 3 3 DTW domain DUF2217 PF10265.4 KEP63368.1 - 0.42 9.3 4.2 0.58 8.8 2.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Herpes_capsid PF06112.6 KEP63368.1 - 7.4 6.6 12.1 16 5.5 8.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein POPLD PF08170.7 KEP63370.1 - 2.3 8.1 4.8 3 7.7 1.4 2.8 1 1 1 2 2 2 0 POPLD (NUC188) domain Dpy-30 PF05186.8 KEP63371.1 - 1.8e-14 52.8 0.4 2.5e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Dpy-30 motif Sulfate_transp PF00916.15 KEP63372.1 - 3.7e-23 81.9 10.4 3.7e-23 81.9 7.2 2.2 2 1 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEP63372.1 - 1.9e-09 37.0 3.9 1.9e-09 37.0 2.7 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEP63372.1 - 0.006 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Ufd2P_core PF10408.4 KEP63374.1 - 8e-129 430.7 0.0 9.7e-129 430.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KEP63374.1 - 2.3e-22 78.7 2.9 5.1e-22 77.6 2.0 1.6 1 0 0 1 1 1 1 U-box domain Ribosomal_60s PF00428.14 KEP63374.1 - 0.002 18.4 4.9 0.0066 16.8 3.4 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 KEP63374.1 - 0.059 13.2 2.5 0.14 11.9 1.7 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MRI PF15325.1 KEP63374.1 - 0.095 13.6 2.3 0.24 12.3 1.6 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection EF-hand_7 PF13499.1 KEP63375.1 - 2.2e-09 37.3 2.8 4.7e-09 36.2 2.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair COPI_assoc PF08507.5 KEP63375.1 - 2.4e-09 37.0 3.7 3.2e-09 36.6 2.6 1.1 1 0 0 1 1 1 1 COPI associated protein EF-hand_1 PF00036.27 KEP63375.1 - 1.4e-08 33.4 2.6 1.1e-05 24.3 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KEP63375.1 - 2.3e-08 33.5 0.9 5.1e-08 32.3 0.6 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KEP63375.1 - 1.3e-07 30.9 2.6 0.00079 19.1 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KEP63375.1 - 3e-05 23.1 1.5 0.00024 20.2 0.1 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 KEP63375.1 - 0.055 13.4 0.3 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region FxsA PF04186.8 KEP63375.1 - 0.07 12.7 0.8 0.35 10.4 0.1 2.3 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein DUF1469 PF07332.6 KEP63375.1 - 0.8 9.4 4.9 0.65 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Complex1_LYR PF05347.10 KEP63376.1 - 0.0015 18.2 0.1 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KEP63376.1 - 0.0045 17.4 1.2 0.062 13.7 0.8 2.1 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KEP63376.1 - 0.071 13.3 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Complex1_LYR-like ACDC PF14733.1 KEP63377.1 - 1.1e-13 51.0 0.0 2.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 KEP63377.1 - 1.7e-11 44.1 0.2 3.2e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 AP2 domain AP2 PF00847.15 KEP63378.1 - 2e-11 43.8 0.2 3.9e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 AP2 domain UQ_con PF00179.21 KEP63380.1 - 2.7e-40 137.0 0.0 2.9e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEP63380.1 - 0.023 14.4 0.1 0.06 13.1 0.1 1.6 1 1 1 2 2 2 0 Prokaryotic E2 family B RWD PF05773.17 KEP63380.1 - 0.033 14.0 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF2353 PF09789.4 KEP63381.1 - 3.6e-06 26.4 34.9 0.00032 20.0 14.0 2.8 1 1 2 3 3 3 2 Uncharacterized coiled-coil protein (DUF2353) BTK PF00779.14 KEP63381.1 - 0.00041 19.8 4.1 0.00096 18.7 2.8 1.6 1 0 0 1 1 1 1 BTK motif BicD PF09730.4 KEP63381.1 - 0.0025 16.2 11.5 0.0025 16.2 8.0 3.2 1 1 2 3 3 3 1 Microtubule-associated protein Bicaudal-D Reo_sigmaC PF04582.7 KEP63381.1 - 0.0042 16.3 13.9 0.13 11.3 4.5 2.2 1 1 1 2 2 2 2 Reovirus sigma C capsid protein FadA PF09403.5 KEP63381.1 - 0.01 15.8 4.0 0.01 15.8 2.8 3.1 2 1 0 2 2 2 0 Adhesion protein FadA YlqD PF11068.3 KEP63381.1 - 0.012 15.6 9.9 0.012 15.6 6.9 3.4 1 1 1 2 2 2 0 YlqD protein APG6 PF04111.7 KEP63381.1 - 0.013 14.5 44.6 0.044 12.8 14.2 2.9 1 1 2 3 3 3 0 Autophagy protein Apg6 ATG16 PF08614.6 KEP63381.1 - 0.02 14.7 41.7 0.075 12.8 3.0 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.1 KEP63381.1 - 0.033 13.3 41.2 0.094 11.8 8.8 3.4 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding zinc_ribbon_2 PF13240.1 KEP63381.1 - 0.041 13.3 1.1 0.14 11.6 0.8 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Spc7 PF08317.6 KEP63381.1 - 0.043 12.4 38.5 0.36 9.4 12.3 2.4 1 1 2 3 3 3 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 KEP63381.1 - 0.086 10.5 46.6 0.014 13.2 10.2 2.1 1 1 0 2 2 2 0 Myosin tail DUF4618 PF15397.1 KEP63381.1 - 0.41 9.9 35.0 0.042 13.1 4.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) V_ATPase_I PF01496.14 KEP63381.1 - 0.42 8.4 30.1 0.99 7.1 10.2 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 KEP63381.1 - 0.71 7.1 41.6 0.23 8.7 10.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KEP63381.1 - 0.87 7.9 29.4 0.79 8.1 8.5 2.1 1 1 1 2 2 2 0 AAA domain FUSC PF04632.7 KEP63381.1 - 1 7.6 26.9 1.9 6.7 18.6 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 KEP63381.1 - 1.1 8.8 51.2 0.13 11.8 8.6 3.4 1 1 2 3 3 3 0 IncA protein Vps51 PF08700.6 KEP63381.1 - 1.2 9.0 16.7 11 5.9 0.8 4.5 3 1 1 4 4 4 0 Vps51/Vps67 Hemerythrin PF01814.18 KEP63381.1 - 1.2 9.2 19.5 4.1 7.5 4.3 3.9 2 1 2 4 4 3 0 Hemerythrin HHE cation binding domain EAP30 PF04157.11 KEP63381.1 - 1.8 7.6 16.8 0.14 11.2 3.1 2.6 2 1 0 2 2 2 0 EAP30/Vps36 family Cast PF10174.4 KEP63381.1 - 1.9 6.4 48.7 1.2 7.1 15.7 2.3 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone Leu_zip PF15294.1 KEP63381.1 - 2.2 7.3 42.3 0.87 8.6 10.3 2.8 1 1 2 3 3 3 0 Leucine zipper AAA_27 PF13514.1 KEP63381.1 - 2.8 5.4 41.6 2.1 5.9 13.1 2.2 1 1 1 2 2 2 0 AAA domain DUF342 PF03961.8 KEP63381.1 - 3 6.1 27.2 2.1 6.6 4.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF342) CCDC155 PF14662.1 KEP63381.1 - 3.9 7.0 45.4 7.2 6.1 11.9 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF2205 PF10224.4 KEP63381.1 - 5.9 6.5 23.9 1.5 8.4 2.1 4.0 2 2 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF1664 PF07889.7 KEP63381.1 - 6.1 6.6 18.0 6.2 6.6 1.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.10 KEP63381.1 - 6.8 6.2 34.4 0.68 9.4 6.7 5.2 2 2 3 5 5 5 0 Septum formation initiator DUF904 PF06005.7 KEP63381.1 - 8.5 6.7 43.5 6.3 7.1 5.5 4.9 1 1 3 4 4 4 0 Protein of unknown function (DUF904) RTBV_P46 PF06216.6 KEP63381.1 - 8.9 5.0 9.1 2.8 6.6 1.6 2.4 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein E1_DerP2_DerF2 PF02221.10 KEP63382.1 - 3.5e-05 24.0 0.0 5.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 ML domain HEAT PF02985.17 KEP63383.1 - 0.15 12.1 8.8 32 4.9 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat PDEase_I PF00233.14 KEP63384.1 - 2.4e-62 210.8 0.3 3.5e-62 210.2 0.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Baculo_LEF-11 PF06385.7 KEP63384.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Baculovirus LEF-11 protein HD PF01966.17 KEP63384.1 - 0.041 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 HD domain Dpy19 PF10034.4 KEP63385.1 - 4.3e-122 408.4 7.2 8.4e-76 255.5 0.1 2.1 2 0 0 2 2 2 2 Q-cell neuroblast polarisation DUF3400 PF11880.3 KEP63385.1 - 0.033 13.4 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) DivIVA PF05103.8 KEP63385.1 - 0.11 12.6 1.0 0.25 11.3 0.7 1.6 1 0 0 1 1 1 0 DivIVA protein PARG_cat PF05028.9 KEP63387.1 - 7.7e-68 229.2 0.1 1.1e-66 225.3 0.1 2.0 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) zf-4CXXC_R1 PF10497.4 KEP63387.1 - 0.024 14.7 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ADIP PF11559.3 KEP63389.1 - 0.11 12.3 4.3 0.19 11.5 3.0 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 KEP63389.1 - 0.12 12.6 2.9 0.26 11.6 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 KEP63389.1 - 1.2 8.6 4.0 2 7.9 2.3 1.7 1 1 0 1 1 1 0 Septum formation initiator NYD-SP28_assoc PF14775.1 KEP63389.1 - 2.5 7.8 4.5 6.2 6.6 1.6 2.2 1 1 1 2 2 2 0 Sperm tail C-terminal domain zf-RING_2 PF13639.1 KEP63391.1 - 9.3e-12 44.5 6.8 9.3e-12 44.5 4.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KEP63391.1 - 3e-07 30.4 7.7 1.9e-06 27.8 5.4 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP63391.1 - 2.1e-06 27.2 5.8 4.4e-06 26.2 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP63391.1 - 1.6e-05 24.4 2.9 4.3e-05 23.0 2.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP63391.1 - 2.4e-05 23.9 4.6 6.2e-05 22.6 3.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP63391.1 - 0.00017 21.5 7.1 0.00017 21.5 4.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEP63391.1 - 0.0054 16.5 3.8 0.017 14.9 2.7 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KEP63391.1 - 0.18 11.7 2.3 0.67 9.9 1.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KEP63391.1 - 0.27 10.9 4.8 0.59 9.8 3.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger adh_short PF00106.20 KEP63392.1 - 5.9e-21 75.1 6.5 2.1e-10 40.7 0.9 2.9 3 1 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 KEP63392.1 - 3.5e-07 30.0 0.8 3.5e-07 30.0 0.6 2.9 3 0 0 3 3 3 1 KR domain adh_short_C2 PF13561.1 KEP63392.1 - 0.0046 16.7 0.1 0.053 13.2 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KEP63392.1 - 0.011 14.6 0.2 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CmcI PF04989.7 KEP63392.1 - 0.054 12.7 0.1 1.9 7.7 0.1 2.1 2 0 0 2 2 2 0 Cephalosporin hydroxylase ExoD PF06055.7 KEP63392.1 - 2.4 7.2 9.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Steroid_dh PF02544.11 KEP63393.1 - 1.7e-35 121.9 3.6 1.4e-34 119.0 2.5 2.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KEP63393.1 - 0.054 12.7 1.9 0.071 12.3 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Abhydrolase_5 PF12695.2 KEP63394.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1129 PF06570.6 KEP63394.1 - 0.1 11.9 1.2 0.15 11.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Tetraspannin PF00335.15 KEP63394.1 - 0.31 10.2 5.2 0.61 9.3 3.3 1.6 1 1 1 2 2 2 0 Tetraspanin family Abhydrolase_5 PF12695.2 KEP63395.1 - 0.00093 18.9 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEP63395.1 - 0.0055 15.9 0.1 0.027 13.7 0.0 1.9 1 1 0 2 2 2 1 Prolyl oligopeptidase family UPF0227 PF05728.7 KEP63395.1 - 0.0074 16.0 0.0 0.74 9.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) UPF0104 PF03706.8 KEP63395.1 - 0.012 14.9 4.7 0.015 14.5 3.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF1700 PF08006.6 KEP63395.1 - 0.045 13.0 0.5 0.085 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF1469 PF07332.6 KEP63395.1 - 0.063 13.0 3.7 0.11 12.2 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF2207 PF09972.4 KEP63395.1 - 0.094 11.2 0.7 0.14 10.7 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 KEP63395.1 - 0.34 10.2 4.6 0.51 9.7 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) KaiC PF06745.8 KEP63396.1 - 0.079 12.0 0.1 0.67 9.0 0.0 2.1 2 0 0 2 2 2 0 KaiC V_ATPase_I PF01496.14 KEP63396.1 - 0.61 7.8 1.3 1.2 6.9 0.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG_C PF09333.6 KEP63397.1 - 2.3e-06 27.6 0.0 6.7e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 KEP63397.1 - 5.9e-05 22.5 0.2 0.00013 21.4 0.2 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Nucleo_P87 PF07267.6 KEP63397.1 - 10 4.6 0.3 22 3.5 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 His_Phos_2 PF00328.17 KEP63399.1 - 2.1e-41 142.4 0.0 7.4e-39 134.0 0.0 3.0 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KEP63399.1 - 0.00016 21.2 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GST_C_3 PF14497.1 KEP63400.1 - 1.4e-16 60.7 0.0 2.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEP63400.1 - 1.4e-08 34.8 0.1 9.2e-08 32.2 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KEP63400.1 - 7.3e-08 32.2 0.3 4.7e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 Glutaredoxin GST_N_2 PF13409.1 KEP63400.1 - 0.00036 20.4 0.0 0.0009 19.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEP63400.1 - 0.0028 17.5 0.0 0.0097 15.7 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Flavodoxin_2 PF02525.12 KEP63400.1 - 0.12 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold GST_C PF00043.20 KEP63400.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LRR_4 PF12799.2 KEP63401.1 - 1.9e-15 56.1 5.0 0.00027 20.4 0.2 3.7 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP63401.1 - 4.1e-08 32.8 6.9 0.00042 20.0 0.7 4.1 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KEP63401.1 - 8.5e-07 28.1 6.0 1.3 9.3 0.0 6.2 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 KEP63401.1 - 2e-06 27.2 5.1 1.4 9.2 0.1 5.6 5 1 1 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 KEP63401.1 - 3.4e-06 26.3 6.8 2.8 8.5 0.0 5.9 7 0 0 7 7 7 2 Leucine rich repeat LRR_3 PF07725.7 KEP63401.1 - 0.81 9.5 3.7 31 4.5 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat Asp_protease PF09668.5 KEP63402.1 - 4.2e-53 178.1 0.0 7.7e-53 177.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KEP63402.1 - 8.8e-11 42.1 0.0 2.3e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KEP63402.1 - 7.8e-10 38.0 0.0 2.6e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.26 KEP63402.1 - 4.5e-08 32.6 1.5 6.2e-08 32.2 0.2 2.0 2 0 0 2 2 2 1 UBA/TS-N domain RVP PF00077.15 KEP63402.1 - 1.5e-06 28.0 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 KEP63402.1 - 3.3e-06 27.0 0.0 5.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KEP63402.1 - 6.7e-05 22.6 0.0 0.00022 20.9 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 KEP63402.1 - 0.0015 18.1 0.0 0.0044 16.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Pex14_N PF04695.8 KEP63402.1 - 0.013 15.4 2.1 0.02 14.9 0.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sipho_Gp157 PF05565.6 KEP63402.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 eRF1_2 PF03464.10 KEP63404.1 - 4.4e-45 153.2 0.1 7.6e-45 152.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KEP63404.1 - 5.7e-37 126.4 0.1 1.3e-36 125.3 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KEP63404.1 - 3.2e-26 91.4 0.1 7.5e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KEP63404.1 - 0.025 14.0 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family N-Term_TEN PF11474.3 KEP63404.1 - 0.056 12.8 0.1 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain DUF3883 PF13020.1 KEP63405.1 - 3.8e-21 74.6 0.0 7.8e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Mob1_phocein PF03637.12 KEP63406.1 - 6e-25 87.9 0.4 9.1e-25 87.3 0.3 1.3 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.20 KEP63407.1 - 6.2e-23 81.2 0.0 8.2e-19 67.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63407.1 - 1.2e-08 34.3 0.0 6.9e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP63407.1 - 0.014 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-C3HC4_3 PF13920.1 KEP63408.1 - 1.8e-11 43.4 7.7 3e-11 42.7 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP63408.1 - 2.6e-06 27.3 12.2 4.8e-06 26.4 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP63408.1 - 0.00071 19.3 11.8 0.0013 18.4 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEP63408.1 - 0.052 13.2 12.7 0.091 12.5 8.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.9 KEP63408.1 - 0.2 11.1 4.8 0.48 9.9 3.3 1.6 1 0 0 1 1 1 0 P-11 zinc finger RRM_1 PF00076.17 KEP63409.1 - 4.4e-15 55.0 0.0 2.7e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP63409.1 - 4.3e-11 42.6 0.0 1.9e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP63409.1 - 1e-06 28.4 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEP63409.1 - 0.071 12.8 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 UQ_con PF00179.21 KEP63410.1 - 3.1e-46 156.2 0.0 3.7e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KEP63410.1 - 0.0012 18.4 0.0 0.0024 17.5 0.0 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 KEP63410.1 - 0.0014 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEP63410.1 - 0.021 14.7 1.0 0.052 13.4 0.7 1.8 1 1 0 1 1 1 0 RWD domain DUF3273 PF11677.3 KEP63414.1 - 2.7e-80 269.4 12.4 3.8e-80 268.9 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) TEX12 PF15219.1 KEP63415.1 - 0.027 14.4 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Testis-expressed 12 VitD-bind_III PF09164.5 KEP63415.1 - 0.064 12.8 0.5 1 9.0 0.1 2.3 2 0 0 2 2 2 0 Vitamin D binding protein, domain III RRM_1 PF00076.17 KEP63416.1 - 1.1e-08 34.5 0.0 7.2e-05 22.3 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP63416.1 - 6.7e-06 25.8 0.1 0.0011 18.7 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP63416.1 - 4.3e-05 23.3 0.0 0.41 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.8 KEP63416.1 - 0.0018 18.7 0.0 0.0038 17.7 0.0 1.5 1 0 0 1 1 1 1 SPOC domain zf-H2C2_2 PF13465.1 KEP63417.1 - 7.6e-19 66.9 9.7 1.3e-05 25.2 0.0 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 KEP63417.1 - 6e-15 54.5 24.3 0.00022 21.3 3.3 5.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEP63417.1 - 9.6e-15 53.7 25.1 0.00081 19.5 0.2 5.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.7 KEP63417.1 - 1.1e-06 28.6 12.6 0.00052 20.0 2.0 2.9 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 KEP63417.1 - 0.0083 16.2 24.3 0.019 15.1 1.0 4.6 4 0 0 4 4 4 2 C2H2-type zinc-finger domain Elf1 PF05129.8 KEP63417.1 - 0.8 9.4 6.1 0.6 9.8 0.1 3.0 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_jaz PF12171.3 KEP63417.1 - 1.9 8.7 16.3 1.9 8.7 1.2 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KEP63417.1 - 2.3 8.0 13.3 0.3 10.8 0.7 3.6 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.2 KEP63417.1 - 4.5 7.4 12.1 9.3 6.4 0.5 3.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KEP63417.1 - 6.3 7.1 18.4 6.3 7.1 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KEP63417.1 - 7.3 6.6 13.5 24 4.9 0.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger UBX PF00789.15 KEP63418.1 - 0.055 13.5 0.4 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 UBX domain Abi PF02517.11 KEP63419.1 - 0.00014 21.9 0.1 0.00014 21.9 0.1 3.3 2 2 0 2 2 2 1 CAAX protease self-immunity OHA PF14418.1 KEP63420.1 - 3.9e-16 58.3 0.0 8.3e-16 57.2 0.0 1.5 1 0 0 1 1 1 1 OST-HTH Associated domain 2-oxoacid_dh PF00198.18 KEP63422.1 - 2.7e-58 196.9 0.1 5.5e-58 195.9 0.1 1.5 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEP63422.1 - 4.3e-52 173.6 15.5 8.5e-19 66.9 0.1 3.7 4 0 0 4 4 3 3 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KEP63422.1 - 5.2e-12 45.2 13.4 0.0023 17.5 0.1 5.9 4 2 2 6 6 6 3 Biotin-lipoyl like HlyD_3 PF13437.1 KEP63422.1 - 7e-07 29.5 5.4 1.5 9.2 0.0 5.9 3 2 2 5 5 5 2 HlyD family secretion protein E3_binding PF02817.12 KEP63422.1 - 1.3e-05 24.6 0.1 4.2e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain PYNP_C PF07831.8 KEP63422.1 - 2e-05 23.9 0.6 1.6 8.2 0.0 3.5 3 0 0 3 3 3 2 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_2 PF12700.2 KEP63422.1 - 3.5e-05 23.1 7.1 1.5 7.8 0.1 5.9 3 3 3 6 6 6 2 HlyD family secretion protein DUF2118 PF09891.4 KEP63422.1 - 0.00015 21.4 1.3 0.46 10.1 0.0 3.4 3 1 0 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2118) GCV_H PF01597.14 KEP63422.1 - 0.00028 20.5 5.2 0.11 12.1 0.0 4.1 4 0 0 4 4 4 1 Glycine cleavage H-protein QRPTase_N PF02749.11 KEP63422.1 - 0.0015 18.3 0.2 1.7 8.5 0.0 3.5 3 1 1 4 4 4 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2254 PF10011.4 KEP63422.1 - 0.0039 15.7 0.0 0.067 11.6 0.0 2.5 3 0 0 3 3 3 1 Predicted membrane protein (DUF2254) DUF515 PF04415.7 KEP63422.1 - 0.068 11.4 7.9 0.086 11.0 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF515) DUF1387 PF07139.6 KEP63422.1 - 0.19 11.3 2.1 0.34 10.4 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Imm5 PF14423.1 KEP63422.1 - 0.22 11.0 0.6 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Immunity protein Imm5 Tmemb_cc2 PF10267.4 KEP63422.1 - 6.4 5.2 7.5 0.16 10.5 0.3 1.8 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF4592 PF15262.1 KEP63422.1 - 7.2 7.1 15.6 0.086 13.3 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) Sigma70_r3 PF04539.11 KEP63423.1 - 1.2e-12 47.5 0.1 9e-12 44.7 0.0 2.6 1 0 0 1 1 1 1 Sigma-70 region 3 Pkinase PF00069.20 KEP63424.1 - 3.5e-76 255.7 0.0 5.6e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63424.1 - 5.5e-37 127.2 0.0 8e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP63424.1 - 6.2e-29 97.0 7.5 1.7e-06 26.8 0.9 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP63424.1 - 2.9e-26 91.3 0.9 7.5e-12 45.2 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP63424.1 - 5.2e-22 75.6 3.6 2.7e-06 26.7 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KEP63424.1 - 3.8e-20 71.2 9.7 1.1e-05 24.8 1.2 4.8 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KEP63424.1 - 1.3e-19 68.5 5.8 2.4e-06 26.6 0.1 4.7 4 0 0 4 4 4 4 EF hand Kinase-like PF14531.1 KEP63424.1 - 3.5e-06 26.2 0.0 1.1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.2 KEP63424.1 - 1.1e-05 25.0 1.8 0.045 13.4 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEP63424.1 - 0.00012 22.0 0.0 0.37 10.8 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 KEP63424.1 - 0.0045 16.0 0.0 0.0092 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP63424.1 - 0.0068 16.1 0.0 0.06 13.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_9 PF14658.1 KEP63424.1 - 0.014 15.2 0.1 0.29 11.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Prenyltransf PF01255.14 KEP63424.1 - 0.019 14.1 0.8 0.025 13.7 0.0 1.5 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase DUF2267 PF10025.4 KEP63424.1 - 0.09 12.8 0.0 0.47 10.5 0.0 2.2 2 1 0 2 2 1 0 Uncharacterized conserved protein (DUF2267) FH2 PF02181.18 KEP63426.1 - 1.1e-42 146.2 2.0 4.2e-36 124.6 0.5 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain PTEN_C2 PF10409.4 KEP63426.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein UBA PF00627.26 KEP63426.1 - 0.56 10.1 0.1 1.4 8.8 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain ABC1 PF03109.11 KEP63426.1 - 0.6 10.0 0.1 1.2 9.0 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Kinesin PF00225.18 KEP63427.1 - 6.2e-83 278.2 0.1 4.3e-82 275.5 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain EF-hand_7 PF13499.1 KEP63428.1 - 2.1e-17 62.9 0.9 3.6e-12 46.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEP63428.1 - 1.3e-14 53.4 0.3 2.4e-10 39.8 0.0 3.2 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP63428.1 - 1.2e-10 39.8 0.2 0.0059 15.8 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KEP63428.1 - 1.9e-10 39.7 1.0 5.8e-05 22.6 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KEP63428.1 - 2.3e-06 26.6 0.0 0.0019 17.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KEP63428.1 - 0.011 15.6 0.0 0.79 9.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.4 KEP63428.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Toprim PF01751.17 KEP63428.1 - 0.13 12.2 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Toprim domain PapD-like PF14874.1 KEP63430.1 - 3.4e-33 113.6 5.7 0.00074 19.4 0.0 14.4 15 0 0 15 15 15 6 Flagellar-associated PapD-like Motile_Sperm PF00635.21 KEP63430.1 - 8.3e-15 54.3 4.9 0.0021 17.6 0.0 11.7 14 0 0 14 14 14 2 MSP (Major sperm protein) domain CARDB PF07705.6 KEP63430.1 - 0.00017 21.5 0.6 3.7 7.6 0.0 7.3 9 0 0 9 9 9 1 CARDB AAA PF00004.24 KEP63430.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MYCBPAP PF14646.1 KEP63430.1 - 0.58 8.8 12.7 0.77 8.4 0.0 5.6 7 0 0 7 7 7 0 MYCBP-associated protein family Macoilin PF09726.4 KEP63430.1 - 2.9 6.0 21.2 5.2 5.2 14.7 1.3 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M16 PF00675.15 KEP63432.1 - 1.5e-21 76.6 0.3 6.3e-21 74.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEP63432.1 - 2.2e-13 50.2 0.7 1.7e-08 34.4 0.0 4.6 5 0 0 5 5 5 3 Peptidase M16 inactive domain UPF0020 PF01170.13 KEP63433.1 - 2.5e-06 27.2 0.0 8.5e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Peptidase_C14 PF00656.17 KEP63434.1 - 1.6e-55 188.5 0.0 3.6e-55 187.3 0.0 1.6 2 0 0 2 2 2 1 Caspase domain DUF2863 PF11062.3 KEP63434.1 - 0.00059 18.0 0.2 0.00095 17.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2863) CUE PF02845.11 KEP63434.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 CUE domain UBA PF00627.26 KEP63434.1 - 0.14 12.0 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain Pyr_redox_2 PF07992.9 KEP63436.1 - 5.9e-39 134.0 6.1 1.4e-37 129.5 4.3 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEP63436.1 - 5.3e-34 116.5 0.0 1.3e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEP63436.1 - 3.3e-24 85.1 8.0 1.7e-20 73.2 0.2 4.0 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEP63436.1 - 2e-12 46.9 0.4 1.4e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEP63436.1 - 1.3e-08 35.1 0.1 6e-07 29.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEP63436.1 - 2.2e-07 30.1 6.9 1.1e-06 27.8 3.2 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEP63436.1 - 4.1e-07 29.2 4.1 4.1e-07 29.2 2.8 3.1 3 2 0 4 4 4 1 FAD binding domain DAO PF01266.19 KEP63436.1 - 6.8e-07 28.5 11.2 0.0038 16.1 0.3 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KEP63436.1 - 4.6e-06 25.3 9.8 0.00037 19.0 1.4 3.8 2 2 1 4 4 4 2 HI0933-like protein Thi4 PF01946.12 KEP63436.1 - 9.1e-06 24.9 0.4 2.6e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KEP63436.1 - 2.7e-05 24.0 7.5 0.0016 18.4 1.6 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEP63436.1 - 0.001 18.1 10.6 0.0079 15.2 0.8 3.1 2 1 1 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 KEP63436.1 - 0.0018 17.2 1.2 0.028 13.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KEP63436.1 - 0.0092 15.5 6.5 0.056 13.0 0.1 3.2 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KEP63436.1 - 0.07 12.7 0.1 0.07 12.7 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEP63436.1 - 0.56 10.4 2.6 6.2 7.1 0.1 2.8 3 0 0 3 3 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KEP63436.1 - 1.4 7.7 4.4 0.52 9.1 0.4 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KEP63436.1 - 3.2 7.1 6.1 1.2 8.5 0.1 2.9 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_C54 PF03416.14 KEP63437.1 - 1.7e-36 125.8 0.0 2.4e-16 59.6 0.0 4.0 4 0 0 4 4 4 3 Peptidase family C54 CPW_WPC PF09717.5 KEP63438.1 - 7.1e-14 52.1 4.9 1.1e-13 51.5 3.2 1.5 1 1 0 1 1 1 1 Plasmodium falciparum domain of unknown function (CPW_WPC) FH2 PF02181.18 KEP63439.1 - 7e-67 225.9 0.3 1.6e-66 224.7 0.2 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain TPR_10 PF13374.1 KEP63439.1 - 5.8e-19 67.3 1.2 4.6e-13 48.6 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEP63439.1 - 3.7e-13 49.1 2.9 5e-08 32.7 0.0 3.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP63439.1 - 0.01 15.6 0.5 56 4.0 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP63439.1 - 0.039 13.5 0.5 27 4.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Myosin_head PF00063.16 KEP63440.1 - 2.8e-121 405.7 0.0 8.1e-50 169.6 0.0 4.1 3 2 0 3 3 3 3 Myosin head (motor domain) IQ PF00612.22 KEP63440.1 - 0.00025 20.4 31.6 0.0023 17.4 0.7 4.9 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_22 PF13401.1 KEP63440.1 - 0.056 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain FAD_binding_7 PF03441.9 KEP63441.1 - 1.2e-34 119.7 0.1 9.6e-34 116.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KEP63441.1 - 9.5e-12 44.9 0.1 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Methyltransf_3 PF01596.12 KEP63441.1 - 0.019 14.0 0.1 0.035 13.1 0.1 1.4 1 0 0 1 1 1 0 O-methyltransferase Hus1 PF04005.7 KEP63442.1 - 3.9e-24 85.1 0.0 8.9e-24 83.9 0.0 1.5 1 1 0 1 1 1 1 Hus1-like protein DNA_pol_phi PF04931.8 KEP63443.1 - 9.9 3.7 3.1 15 3.2 2.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi RF-1 PF00472.15 KEP63444.1 - 1.8e-18 66.4 12.6 4.9e-18 64.9 8.7 1.7 1 1 0 1 1 1 1 RF-1 domain Peptidase_S49_N PF08496.5 KEP63444.1 - 2 8.1 6.6 3.2 7.5 4.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1682 PF07946.9 KEP63444.1 - 3.8 6.2 11.2 5.3 5.7 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ER_lumen_recept PF00810.13 KEP63445.1 - 6.8e-24 85.0 10.0 1.1e-23 84.3 6.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KEP63445.1 - 0.0043 16.5 4.8 0.38 10.3 0.3 2.9 2 1 0 2 2 2 2 PQ loop repeat zf-rbx1 PF12678.2 KEP63447.1 - 9.1e-08 32.0 1.9 9.1e-08 32.0 1.3 3.4 3 1 1 4 4 4 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEP63447.1 - 6.7e-07 29.0 5.0 6.7e-07 29.0 3.5 3.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KEP63447.1 - 0.0038 16.8 3.9 0.0038 16.8 2.7 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP63447.1 - 0.0048 16.8 6.8 0.0048 16.8 4.7 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEP63447.1 - 0.0049 16.6 2.1 0.0049 16.6 1.5 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger UbiA PF01040.13 KEP63450.1 - 2e-21 76.3 15.7 2e-21 76.3 10.9 1.6 2 0 0 2 2 2 1 UbiA prenyltransferase family Nol1_Nop2_Fmu PF01189.12 KEP63451.1 - 3.4e-14 52.9 0.2 1.2e-06 28.1 0.0 3.2 3 0 0 3 3 3 3 NOL1/NOP2/sun family Laminin_G_3 PF13385.1 KEP63453.1 - 8.7e-14 52.0 0.0 1.7e-13 51.1 0.0 1.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 KEP63453.1 - 9.2e-06 25.7 0.0 2.7e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.18 KEP63453.1 - 0.0038 17.2 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Laminin G domain Sin3_corepress PF08295.7 KEP63454.1 - 3.2e-22 78.1 0.0 8.1e-22 76.8 0.0 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor DUF1620 PF07774.8 KEP63455.1 - 7.6e-43 146.2 0.0 1.2e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KEP63455.1 - 7.1e-10 38.7 4.0 0.00011 21.7 0.4 3.3 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 KEP63455.1 - 0.00016 20.9 1.0 2.3 7.9 0.0 4.6 4 0 0 4 4 4 1 PQQ enzyme repeat Misat_Tub_SegII PF10644.4 KEP63455.1 - 0.23 11.5 0.0 0.55 10.2 0.0 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain A_deaminase PF00962.17 KEP63457.1 - 7e-39 133.6 0.0 9.3e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase tRNA-synt_2 PF00152.15 KEP63458.1 - 3.3e-89 298.9 0.0 4.3e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEP63458.1 - 2.9e-11 43.0 0.1 5e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEP63458.1 - 9e-08 31.6 0.0 0.00014 21.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KEP63458.1 - 0.019 14.5 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Pro_isomerase PF00160.16 KEP63459.1 - 9.4e-48 162.3 0.0 1e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 KEP63459.1 - 0.042 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain FA_desaturase PF00487.19 KEP63460.1 - 0.011 15.2 2.0 0.016 14.6 1.4 1.3 1 0 0 1 1 1 0 Fatty acid desaturase SF-assemblin PF06705.6 KEP63462.1 - 3.9e-42 144.0 22.5 4.8e-42 143.8 15.6 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 KEP63462.1 - 0.38 10.5 12.5 3.7 7.3 0.7 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bcr-Abl_Oligo PF09036.5 KEP63462.1 - 0.51 10.3 3.9 0.27 11.2 0.3 2.3 2 2 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Occludin_ELL PF07303.8 KEP63462.1 - 2.2 9.0 11.7 2.3 9.0 0.6 3.0 1 1 2 3 3 3 0 Occludin homology domain DUF1409 PF07197.7 KEP63462.1 - 2.3 8.3 7.8 10 6.2 0.1 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF1409) F5_F8_type_C PF00754.20 KEP63463.1 - 2e-05 24.4 0.1 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Ricin_B_lectin PF00652.17 KEP63463.1 - 7.3e-05 22.7 0.1 0.00017 21.6 0.1 1.6 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain ACDC PF14733.1 KEP63464.1 - 1.4e-17 63.5 0.1 2.4e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 KEP63464.1 - 1.5e-12 47.4 0.6 7.6e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 AP2 domain OATP PF03137.15 KEP63466.1 - 6.8e-12 44.2 0.6 0.00052 18.2 0.0 4.3 4 1 1 5 5 5 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 KEP63466.1 - 2.6e-10 39.5 36.4 6.3e-07 28.4 1.3 3.9 3 2 0 3 3 3 3 Major Facilitator Superfamily Pex14_N PF04695.8 KEP63466.1 - 0.18 11.8 16.2 0.067 13.2 1.9 3.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med3 PF11593.3 KEP63466.1 - 2.6 7.1 9.6 6 5.9 6.7 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-C3HC4_2 PF13923.1 KEP63468.1 - 3e-12 46.3 8.2 5e-12 45.6 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP63468.1 - 3e-11 42.9 9.2 4.8e-11 42.2 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEP63468.1 - 5.1e-11 42.0 6.0 9.3e-11 41.2 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP63468.1 - 3.6e-10 39.3 6.3 5.8e-10 38.6 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP63468.1 - 1.8e-09 37.1 6.5 3.2e-09 36.3 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEP63468.1 - 1.4e-07 31.0 3.5 9.7e-07 28.4 0.3 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEP63468.1 - 2.2e-06 27.4 5.7 4.2e-06 26.5 3.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KEP63468.1 - 0.00035 20.6 4.9 0.00062 19.8 3.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 KEP63468.1 - 0.0047 16.1 0.1 0.0047 16.1 0.1 2.3 2 0 0 2 2 1 1 Rtf2 RING-finger MIP-T3 PF10243.4 KEP63468.1 - 0.011 14.2 22.5 0.015 13.8 15.6 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-RING_4 PF14570.1 KEP63468.1 - 0.023 14.2 7.7 0.053 13.1 5.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KEP63468.1 - 0.023 14.1 5.1 0.042 13.3 3.6 1.3 1 0 0 1 1 1 0 P-11 zinc finger U-box PF04564.10 KEP63468.1 - 0.049 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-Apc11 PF12861.2 KEP63468.1 - 0.066 13.0 2.9 0.12 12.2 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KEP63468.1 - 0.076 12.8 3.7 0.13 12.0 2.6 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 KEP63468.1 - 0.27 10.7 6.6 0.53 9.8 4.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 KEP63468.1 - 0.62 9.7 2.5 0.99 9.1 1.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-CHY PF05495.7 KEP63468.1 - 1.2 9.2 6.1 2.4 8.3 4.2 1.4 1 0 0 1 1 1 0 CHY zinc finger IBR PF01485.16 KEP63468.1 - 2.5 8.0 8.5 8.3 6.3 5.8 2.0 1 1 0 1 1 1 0 IBR domain SAPS PF04499.10 KEP63468.1 - 3.3 6.2 7.3 4.2 5.8 5.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NYD-SP28 PF14772.1 KEP63469.1 - 0.021 14.8 5.2 0.021 14.8 3.6 3.5 1 1 2 3 3 3 0 Sperm tail DegT_DnrJ_EryC1 PF01041.12 KEP63469.1 - 0.19 10.7 9.5 0.26 10.2 6.3 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fib_alpha PF08702.5 KEP63469.1 - 0.2 11.7 20.4 0.033 14.2 3.6 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 KEP63469.1 - 1.5 8.6 5.3 1 9.1 0.5 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 KEP63469.1 - 5.4 4.2 41.9 0.13 9.5 20.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Arm PF00514.18 KEP63470.1 - 1.3e-05 24.7 5.7 0.27 11.1 0.0 8.1 11 0 0 11 11 11 2 Armadillo/beta-catenin-like repeat PSD5 PF07637.6 KEP63470.1 - 0.091 12.8 1.0 0.7 9.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) Mg_trans_NIPA PF05653.9 KEP63471.1 - 1.1e-16 60.6 9.5 9.2e-10 37.9 1.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF973 PF06157.6 KEP63471.1 - 0.0014 17.6 0.3 0.0028 16.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF973) TRAUB PF08164.7 KEP63472.1 - 1.3e-15 57.2 0.9 3.1e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KEP63472.1 - 2.6e-09 37.3 0.5 2.6e-09 37.3 0.4 2.7 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor HSP20 PF00011.16 KEP63473.1 - 3.7e-22 78.1 0.1 5e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 KEP63473.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 BON domain CLASP_N PF12348.3 KEP63474.1 - 1.8e-12 47.1 0.6 3.1e-12 46.3 0.4 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.1 KEP63474.1 - 0.063 13.5 2.4 0.7 10.2 0.1 3.3 4 0 0 4 4 4 0 HEAT repeats Pkinase PF00069.20 KEP63476.1 - 5.5e-58 196.1 0.0 6.6e-34 117.2 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63476.1 - 2.3e-23 82.6 0.0 9.7e-22 77.2 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.9 KEP63476.1 - 0.26 10.3 0.1 0.9 8.5 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IF4E PF01652.13 KEP63477.1 - 7e-11 41.9 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E EGF_2 PF07974.8 KEP63478.1 - 1.7e-21 76.0 106.1 2.7e-05 24.2 5.7 6.2 6 0 0 6 6 6 6 EGF-like domain hEGF PF12661.2 KEP63478.1 - 1.1 9.4 56.6 0.15 12.2 1.6 7.0 6 0 0 6 6 6 0 Human growth factor-like EGF RRM_1 PF00076.17 KEP63479.1 - 9.7e-39 130.8 0.1 1.1e-16 60.2 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP63479.1 - 2.3e-30 104.2 0.0 3.7e-09 36.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP63479.1 - 6.6e-28 96.4 0.0 2e-12 46.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KEP63479.1 - 0.0017 18.5 0.1 0.0017 18.5 0.1 2.5 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.1 KEP63479.1 - 0.0055 16.4 0.1 2.9 7.7 0.0 2.9 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEP63479.1 - 0.0065 16.3 0.0 1.4 8.7 0.0 3.0 2 0 0 2 2 2 1 RNA binding motif IPPT PF01715.12 KEP63480.1 - 1.3e-49 168.5 0.1 6.5e-47 159.6 0.0 3.0 3 0 0 3 3 3 1 IPP transferase zf-C2H2_jaz PF12171.3 KEP63480.1 - 4.2e-06 26.7 0.3 1.1e-05 25.4 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEP63480.1 - 1.4e-05 25.0 1.2 3.7e-05 23.7 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PhoH PF02562.11 KEP63480.1 - 0.00081 18.6 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 KEP63480.1 - 0.0015 18.6 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain IPT PF01745.11 KEP63480.1 - 0.002 17.3 0.2 0.0088 15.2 0.0 2.0 2 0 0 2 2 2 1 Isopentenyl transferase AAA_19 PF13245.1 KEP63480.1 - 0.013 15.2 0.5 0.13 12.0 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 KEP63480.1 - 0.014 15.3 0.5 0.047 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 KEP63480.1 - 0.064 13.4 0.0 12 6.1 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEP63480.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEP63480.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SRP54 PF00448.17 KEP63480.1 - 0.086 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 KEP63480.1 - 0.094 12.5 0.8 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEP63480.1 - 0.13 12.6 0.4 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEP63480.1 - 0.23 11.1 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KEP63480.1 - 0.32 11.8 4.3 0.64 10.8 1.3 2.6 2 1 0 2 2 2 0 AAA domain Ku_PK_bind PF08785.6 KEP63481.1 - 2.1e-17 63.1 0.1 2.1e-09 37.3 0.0 2.6 2 0 0 2 2 2 2 Ku C terminal domain like Ku PF02735.11 KEP63481.1 - 1.3e-12 47.5 0.0 3.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA_2 PF13519.1 KEP63481.1 - 0.00047 20.3 0.0 0.0089 16.1 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Ku_N PF03731.10 KEP63481.1 - 0.0008 18.9 0.0 0.0034 16.8 0.0 1.9 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.23 KEP63481.1 - 0.082 12.6 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF3639 PF12341.3 KEP63482.1 - 1.1e-05 25.2 1.7 1.6e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) MIP-T3 PF10243.4 KEP63483.1 - 0.00017 20.2 27.0 0.0002 19.9 18.7 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF936 PF06075.7 KEP63483.1 - 5.8 5.7 26.8 7.4 5.3 18.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) UPRTase PF14681.1 KEP63484.1 - 9.1e-80 266.7 0.0 1.1e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KEP63484.1 - 0.00063 19.4 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PucR PF07905.6 KEP63485.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family TPR_12 PF13424.1 KEP63486.1 - 3.2e-06 27.0 0.1 6.4e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-MYND PF01753.13 KEP63486.1 - 3.1e-05 23.7 2.6 6e-05 22.8 1.8 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KEP63486.1 - 0.00058 19.6 2.4 0.0014 18.4 1.7 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1460 PF07313.7 KEP63486.1 - 0.0073 15.5 0.0 0.0083 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1460) zf-HIT PF04438.11 KEP63486.1 - 0.013 15.1 6.6 0.025 14.2 4.6 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-B_box PF00643.19 KEP63486.1 - 0.27 11.1 3.2 0.49 10.3 2.3 1.4 1 0 0 1 1 1 0 B-box zinc finger C1_3 PF07649.7 KEP63486.1 - 6.4 6.9 8.2 18 5.4 5.7 1.8 1 1 0 1 1 1 0 C1-like domain 60KD_IMP PF02096.15 KEP63488.1 - 5.6e-09 35.9 0.1 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2183 PF09949.4 KEP63489.1 - 0.00018 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Methyltransf_16 PF10294.4 KEP63490.1 - 1.3e-09 37.7 0.0 5.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 KEP63490.1 - 0.00064 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KEP63490.1 - 0.00093 18.9 0.0 0.0024 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP63490.1 - 0.0014 19.2 0.0 0.0031 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KEP63490.1 - 0.0033 16.8 0.1 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 KEP63490.1 - 0.014 15.7 0.0 0.13 12.6 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_9 PF08003.6 KEP63490.1 - 0.023 13.4 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.1 KEP63490.1 - 0.084 12.4 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 KEP63490.1 - 0.096 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KEP63490.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_11 PF13414.1 KEP63493.1 - 6.5e-12 44.9 2.4 5.1e-08 32.4 0.1 2.6 1 1 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.1 KEP63493.1 - 1.4e-08 34.4 2.5 3.6e-05 23.5 0.6 2.4 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 KEP63493.1 - 6.8e-08 31.7 4.0 0.0057 16.2 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEP63493.1 - 1.1e-07 31.6 6.8 0.00012 21.9 1.7 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEP63493.1 - 2.9e-07 30.7 3.1 5e-07 29.9 0.6 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP63493.1 - 9.8e-07 29.2 1.5 0.0011 19.6 0.1 3.5 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEP63493.1 - 1e-06 28.1 6.3 0.011 15.5 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEP63493.1 - 2.2e-06 27.0 3.9 0.00028 20.4 0.3 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP63493.1 - 2.6e-05 24.4 5.6 0.00046 20.5 0.6 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEP63493.1 - 0.0017 18.6 2.1 0.012 16.0 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 KEP63493.1 - 0.0048 15.7 1.1 0.0093 14.7 0.8 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.1 KEP63493.1 - 0.012 15.3 0.1 0.51 10.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 KEP63493.1 - 0.084 12.6 1.6 0.26 11.1 0.2 2.3 2 1 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Apc3 PF12895.2 KEP63493.1 - 0.085 13.0 0.7 0.32 11.1 0.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KEP63493.1 - 0.16 12.2 0.5 9.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEP63493.1 - 4.4 7.3 5.4 65 3.6 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEP63493.1 - 4.9 7.0 12.1 0.84 9.5 0.9 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.17 KEP63494.1 - 4.2e-22 78.7 0.0 1.9e-21 76.5 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase AAA PF00004.24 KEP63495.1 - 1.7e-07 31.5 0.0 0.006 16.7 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) UPF0029 PF01205.14 KEP63496.1 - 6.4e-24 83.7 2.4 1.4e-22 79.4 1.7 2.3 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KEP63496.1 - 8.8e-07 28.8 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain AAA PF00004.24 KEP63499.1 - 1.9e-36 125.1 0.0 5.6e-36 123.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEP63499.1 - 4.5e-06 25.8 0.0 1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEP63499.1 - 7.3e-06 25.5 1.3 0.0029 17.0 0.2 2.5 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 KEP63499.1 - 1.4e-05 25.2 1.1 0.00023 21.3 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KEP63499.1 - 0.00028 20.6 0.0 0.0009 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEP63499.1 - 0.00073 19.4 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KEP63499.1 - 0.00085 19.2 0.3 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain CENP-F_leu_zip PF10473.4 KEP63499.1 - 0.0013 18.5 2.0 0.0029 17.4 1.4 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_17 PF13207.1 KEP63499.1 - 0.0016 19.2 0.0 0.0046 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP63499.1 - 0.0016 18.4 3.5 0.0029 17.6 0.1 3.1 3 2 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 KEP63499.1 - 0.002 16.9 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KEP63499.1 - 0.0034 17.2 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEP63499.1 - 0.0052 16.5 0.1 0.023 14.4 0.1 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEP63499.1 - 0.0056 16.9 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KEP63499.1 - 0.012 15.6 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 KEP63499.1 - 0.015 15.2 0.8 0.032 14.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KEP63499.1 - 0.022 14.3 0.8 0.14 11.7 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KEP63499.1 - 0.032 13.4 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KEP63499.1 - 0.037 13.6 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEP63499.1 - 0.043 12.9 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 KEP63499.1 - 0.047 13.1 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Prominin PF05478.6 KEP63499.1 - 0.065 10.7 0.8 0.098 10.1 0.5 1.1 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.1 KEP63499.1 - 0.089 11.2 0.9 3.8 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEP63499.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Zot PF05707.7 KEP63499.1 - 0.15 11.5 0.2 4.1 6.8 0.1 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KEP63499.1 - 0.19 11.1 0.5 0.77 9.1 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain SKI PF01202.17 KEP63499.1 - 0.22 11.3 0.0 0.22 11.3 0.0 3.1 4 0 0 4 4 3 0 Shikimate kinase DivIC PF04977.10 KEP63499.1 - 0.33 10.4 3.3 0.79 9.2 2.3 1.6 1 0 0 1 1 1 0 Septum formation initiator KaiC PF06745.8 KEP63499.1 - 0.94 8.5 2.3 3 6.9 0.0 2.4 2 1 1 3 3 3 0 KaiC Sec7 PF01369.15 KEP63500.1 - 1.6e-45 155.0 0.0 2.3e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.13 KEP63501.1 - 1.4e-26 93.2 0.1 2.9e-26 92.2 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BROMI PF14961.1 KEP63501.1 - 0.023 11.8 0.4 0.032 11.3 0.3 1.0 1 0 0 1 1 1 0 Broad-minded protein OB_NTP_bind PF07717.11 KEP63502.1 - 4.7e-30 103.7 0.0 1.7e-29 101.9 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEP63502.1 - 1.3e-29 102.2 0.0 4.4e-29 100.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEP63502.1 - 6.6e-10 38.7 0.0 2e-09 37.1 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEP63502.1 - 8.2e-07 29.2 0.0 2.6e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain S1 PF00575.18 KEP63502.1 - 1.9e-05 24.6 0.4 5.8e-05 23.1 0.3 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KEP63502.1 - 0.00058 19.3 0.4 0.0028 17.1 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KEP63502.1 - 0.0009 18.2 0.0 0.0025 16.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 KEP63502.1 - 0.0073 16.6 0.2 0.98 9.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 KEP63502.1 - 0.025 14.3 0.3 0.099 12.4 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 KEP63502.1 - 0.074 12.4 0.1 4.9 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 KEP63502.1 - 0.077 12.2 0.0 0.21 10.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 KEP63502.1 - 0.084 12.7 0.0 0.4 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 KEP63502.1 - 1.1 8.3 3.4 2.1 7.4 2.4 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein WD40 PF00400.27 KEP63504.1 - 0.056 13.3 10.0 3.2 7.7 0.2 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat U79_P34 PF03064.11 KEP63504.1 - 6.4 6.2 14.9 16 4.9 10.3 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TFIIS_C PF01096.13 KEP63505.1 - 4.3e-19 67.8 9.1 4.3e-19 67.8 6.3 3.5 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KEP63505.1 - 6.6e-09 35.3 0.9 6.6e-09 35.3 0.7 2.5 3 0 0 3 3 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 KEP63505.1 - 0.0019 17.9 13.5 0.051 13.3 3.9 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DUF2387 PF09526.5 KEP63505.1 - 0.015 15.2 8.6 0.3 11.0 0.9 2.2 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-H2C2_5 PF13909.1 KEP63505.1 - 0.035 14.3 0.6 0.035 14.3 0.4 3.4 4 0 0 4 4 3 0 C2H2-type zinc-finger domain Baculo_LEF5_C PF11792.3 KEP63505.1 - 0.036 13.4 2.8 0.036 13.4 2.0 2.3 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_4 PF13717.1 KEP63505.1 - 0.16 11.6 0.2 0.16 11.6 0.1 4.0 4 0 0 4 4 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KEP63505.1 - 0.31 10.6 0.2 0.31 10.6 0.2 4.0 4 0 0 4 4 3 0 zinc-ribbon domain DUF3716 PF12511.3 KEP63505.1 - 3.3 7.4 12.5 0.098 12.2 4.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) HypA PF01155.14 KEP63505.1 - 3.4 7.3 12.7 0.025 14.2 2.4 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Terminase_GpA PF05876.7 KEP63505.1 - 5.1 5.3 9.2 1.1 7.5 4.4 1.4 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) PADR1 PF08063.7 KEP63505.1 - 8.9 5.7 11.8 1.7 8.0 0.5 2.6 2 1 0 2 2 2 0 PADR1 (NUC008) domain DNA_topoisoIV PF00521.15 KEP63508.1 - 1.4e-125 419.4 0.0 2.1e-125 418.9 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KEP63508.1 - 3.3e-31 107.8 3.3 8e-31 106.5 2.3 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KEP63508.1 - 2.9e-14 52.8 0.0 1e-13 51.0 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KEP63508.1 - 1.7e-07 30.9 0.1 1.4e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tim17 PF02466.14 KEP63509.1 - 8.5e-30 103.4 2.2 1.3e-29 102.8 1.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.1 KEP63509.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Cript PF10235.4 KEP63510.1 - 0.013 15.8 0.1 0.64 10.4 0.0 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Metallophos PF00149.23 KEP63511.1 - 7.6e-37 126.6 0.1 1e-36 126.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 KEP63511.1 - 2.4e-17 62.3 2.3 3.3e-11 42.6 0.1 2.6 1 1 1 2 2 2 2 TPR repeat PPP5 PF08321.7 KEP63511.1 - 8.4e-13 48.1 0.0 2.4e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 KEP63511.1 - 3.6e-12 45.3 4.4 2.7e-06 26.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP63511.1 - 6.7e-12 44.3 0.6 8.8e-06 25.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3808 PF10300.4 KEP63511.1 - 7.3e-06 24.8 0.8 1.1e-05 24.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 KEP63511.1 - 0.0049 16.7 0.3 0.071 13.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP63511.1 - 0.0072 16.4 0.6 0.019 15.1 0.1 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP63511.1 - 0.01 15.5 0.1 1.5 8.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEP63511.1 - 0.011 15.5 0.2 0.04 13.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP63511.1 - 0.027 14.2 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Cohesin_HEAT PF12765.2 KEP63512.1 - 0.014 15.3 3.1 5.5 7.0 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KEP63512.1 - 0.091 12.8 10.7 11 6.4 0.0 6.1 5 0 0 5 5 5 0 HEAT repeat Trs65 PF12735.2 KEP63516.1 - 1.3e-12 47.7 5.1 5.1e-12 45.7 0.0 3.0 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 GED PF02212.13 KEP63516.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain RNase_Zc3h12a PF11977.3 KEP63517.1 - 1.4e-12 47.6 0.0 2.1e-06 27.6 0.0 2.9 3 1 0 3 3 3 2 Zc3h12a-like Ribonuclease NYN domain Thioredoxin_8 PF13905.1 KEP63518.1 - 1.5e-42 143.6 0.0 1e-24 86.4 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KEP63518.1 - 3.5e-10 40.0 0.0 5.8e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 KEP63518.1 - 2e-07 30.6 0.0 2.9e-05 23.6 0.1 2.6 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.5 KEP63518.1 - 5.6e-07 29.2 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEP63518.1 - 1.1e-05 25.1 0.0 4.2e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.9 KEP63518.1 - 0.0023 17.5 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_9 PF14595.1 KEP63518.1 - 0.004 16.7 0.0 0.016 14.7 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 KEP63518.1 - 0.0056 16.6 1.2 0.076 13.0 0.1 3.3 3 1 0 3 3 3 1 Thioredoxin-like Glutaredoxin PF00462.19 KEP63518.1 - 0.039 13.9 0.1 0.44 10.5 0.0 2.8 4 0 0 4 4 4 0 Glutaredoxin E1-E2_ATPase PF00122.15 KEP63520.1 - 6.3e-57 192.2 0.3 6.5e-56 188.9 0.1 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEP63520.1 - 2.3e-32 112.0 0.1 2.3e-32 112.0 0.1 3.9 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEP63520.1 - 1.7e-25 90.6 0.0 1.3e-24 87.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP63520.1 - 1e-13 51.8 1.2 6.6e-13 49.2 1.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP63520.1 - 2.3e-12 46.6 0.0 4.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KEP63520.1 - 1.5e-05 24.3 0.0 5.8e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEP63520.1 - 1.6e-05 24.6 0.8 0.00019 21.1 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L14 PF00238.14 KEP63521.1 - 6.1e-32 109.9 0.0 6.7e-32 109.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ras PF00071.17 KEP63524.1 - 1.3e-59 200.2 0.0 1.5e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP63524.1 - 1.1e-16 61.3 0.0 1.7e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP63524.1 - 7.3e-12 44.8 0.0 9.5e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEP63524.1 - 0.00025 20.9 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KEP63524.1 - 0.00085 18.5 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEP63524.1 - 0.0034 16.8 0.0 0.019 14.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 KEP63524.1 - 0.062 12.8 0.0 0.094 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEP63524.1 - 0.096 12.8 0.1 0.23 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain GRAM PF02893.15 KEP63526.1 - 1.6e-10 40.3 0.1 3.1e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 GRAM domain SH3_2 PF07653.12 KEP63526.1 - 0.00012 21.5 0.1 0.0003 20.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Orthopox_A43R PF06517.6 KEP63526.1 - 2.2 7.7 0.0 3.6 7.1 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A43R protein Nop14 PF04147.7 KEP63527.1 - 0.69 7.7 51.6 0.93 7.3 35.8 1.2 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 KEP63527.1 - 1 8.7 27.2 1.1 8.6 18.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 KEP63527.1 - 1.2 8.4 42.0 1.4 8.1 29.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-T PF15511.1 KEP63527.1 - 1.5 7.9 33.2 1.7 7.8 23.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Raftlin PF15250.1 KEP63527.1 - 4.4 5.7 13.4 5.1 5.5 9.3 1.0 1 0 0 1 1 1 0 Raftlin MIP-T3 PF10243.4 KEP63527.1 - 6.5 5.0 30.7 6.8 5.0 21.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NOA36 PF06524.7 KEP63529.1 - 1.2 8.3 6.3 2.4 7.3 4.3 1.4 1 0 0 1 1 1 0 NOA36 protein BACK PF07707.10 KEP63530.1 - 0.031 14.1 0.1 0.26 11.1 0.0 2.4 3 0 0 3 3 3 0 BTB And C-terminal Kelch GYF PF02213.11 KEP63530.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 GYF domain WD40 PF00400.27 KEP63531.1 - 7.1e-24 82.7 10.1 1.4e-07 31.1 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KEP63531.1 - 2.7e-16 59.2 0.0 8e-16 57.7 0.0 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Prion_bPrPp PF11587.3 KEP63531.1 - 0.072 12.7 0.9 0.93 9.2 0.1 2.6 3 0 0 3 3 3 0 Major prion protein bPrPp - N terminal Apc4_WD40 PF12894.2 KEP63531.1 - 0.09 12.2 0.0 7.5 6.1 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF789 PF05623.7 KEP63532.1 - 5.3e-14 52.3 2.6 5.2e-08 32.7 0.0 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF789) TMF_TATA_bd PF12325.3 KEP63535.1 - 0.00025 20.7 3.9 0.00047 19.8 2.7 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 KEP63535.1 - 0.0058 15.6 6.1 0.0059 15.5 4.2 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 KLRAQ PF10205.4 KEP63535.1 - 0.0081 16.1 6.1 0.0081 16.1 4.2 1.7 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein GSK-3_bind PF05350.7 KEP63535.1 - 0.016 14.6 0.8 0.025 14.0 0.5 1.4 1 1 0 1 1 1 0 Glycogen synthase kinase-3 binding Ribosomal_L30 PF00327.15 KEP63535.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e DivIC PF04977.10 KEP63535.1 - 0.053 13.0 2.5 0.093 12.2 1.7 1.5 1 0 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.4 KEP63535.1 - 0.096 12.5 5.5 0.16 11.8 3.8 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain FliJ PF02050.11 KEP63535.1 - 0.1 12.6 14.8 0.16 12.0 10.3 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Seryl_tRNA_N PF02403.17 KEP63535.1 - 0.17 11.9 9.0 0.046 13.7 4.0 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 KEP63535.1 - 0.38 10.5 8.7 0.81 9.4 6.0 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KEP63535.1 - 0.68 8.9 4.6 0.71 8.8 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4407 PF14362.1 KEP63535.1 - 1 8.2 5.9 1.3 7.9 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.1 KEP63535.1 - 1.1 9.2 6.3 0.55 10.2 2.9 1.6 1 1 0 1 1 1 0 FlxA-like protein RTBV_P46 PF06216.6 KEP63535.1 - 1.1 7.9 3.3 1.5 7.6 2.3 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Pneumo_ncap PF03246.8 KEP63537.1 - 0.13 10.8 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein PPTA PF01239.17 KEP63538.1 - 0.0054 16.0 0.3 0.49 9.8 0.0 3.1 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat Exo_endo_phos PF03372.18 KEP63539.1 - 7.5e-10 39.1 0.1 1.2e-09 38.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PCI PF01399.22 KEP63540.1 - 0.00063 20.0 0.0 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 PCI domain KaiC PF06745.8 KEP63540.1 - 0.069 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 KaiC ADH_zinc_N PF00107.21 KEP63541.1 - 6e-24 84.0 0.1 1.1e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEP63541.1 - 5.4e-20 71.1 0.7 1.4e-19 69.8 0.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEP63541.1 - 2.5e-05 25.1 0.0 5.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KEP63541.1 - 0.027 14.0 1.9 0.11 12.0 0.1 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KEP63541.1 - 0.032 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KEP63541.1 - 0.034 13.3 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Macro PF01661.16 KEP63541.1 - 0.068 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Macro domain UDPG_MGDP_dh_N PF03721.9 KEP63541.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VPEP PF07589.6 KEP63541.1 - 4 7.4 5.0 1.1 9.2 0.3 2.3 2 0 0 2 2 2 0 PEP-CTERM motif DUF4659 PF15558.1 KEP63542.1 - 0.95 8.0 12.7 1.4 7.5 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) DUF4519 PF15012.1 KEP63543.1 - 0.16 11.8 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Mago-bind PF09282.5 KEP63545.1 - 1.5e-14 53.2 8.4 3.5e-14 52.0 3.2 2.5 2 0 0 2 2 2 2 Mago binding Lactamase_B_2 PF12706.2 KEP63547.1 - 0.00044 19.8 0.0 0.0019 17.7 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HSP70 PF00012.15 KEP63548.1 - 5.6e-265 879.9 13.5 6.5e-265 879.7 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEP63548.1 - 9.4e-22 77.0 0.6 9.4e-22 77.0 0.4 2.5 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.11 KEP63548.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KEP63548.1 - 0.039 13.7 7.3 3.5 7.4 0.0 4.3 3 1 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.13 KEP63548.1 - 0.041 12.9 3.2 0.086 11.9 0.1 2.8 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Effector_1 PF04518.7 KEP63548.1 - 0.8 8.6 5.5 0.36 9.7 0.2 2.2 2 0 0 2 2 2 0 Effector from type III secretion system Peptidase_C97 PF05903.9 KEP63553.1 - 2.3e-39 134.5 0.0 3.7e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.5 KEP63553.1 - 4.4e-10 39.1 0.1 1.3e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 PUB domain UBA PF00627.26 KEP63553.1 - 1.1e-06 28.3 0.3 3.6e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 KEP63553.1 - 0.021 14.3 0.3 0.059 12.9 0.2 1.7 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.11 KEP63553.1 - 0.031 13.7 0.3 0.081 12.4 0.2 1.8 1 0 0 1 1 1 0 CUE domain DUF770 PF05591.7 KEP63553.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF770) FUN14 PF04930.10 KEP63554.1 - 6.8e-19 67.9 0.0 1.1e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 FUN14 family SET PF00856.23 KEP63556.1 - 2.8e-18 66.7 0.2 2.8e-18 66.7 0.1 4.6 4 3 0 4 4 4 1 SET domain LRR_6 PF13516.1 KEP63557.1 - 1.1e-06 28.0 4.6 0.074 13.1 0.1 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 KEP63557.1 - 0.00077 19.0 9.8 0.038 13.6 0.7 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KEP63557.1 - 0.1 12.8 7.3 5.6 7.6 0.0 4.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 KEP63557.1 - 0.19 11.5 8.4 1.9 8.2 0.4 3.2 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 KEP63557.1 - 0.72 10.1 12.5 9.6 6.6 0.3 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat WD40 PF00400.27 KEP63558.1 - 5.5e-10 38.7 11.5 0.00022 20.9 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-HC5HC2H_2 PF13832.1 KEP63558.1 - 7.9e-07 29.0 1.1 2.5e-06 27.4 0.8 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain Bromodomain PF00439.20 KEP63558.1 - 6.4e-06 26.0 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.1 KEP63558.1 - 1.4e-05 25.1 1.4 4.1e-05 23.6 1.0 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.24 KEP63558.1 - 0.011 15.4 3.5 0.071 12.8 1.8 2.7 2 0 0 2 2 2 0 PHD-finger Peptidase_S49_N PF08496.5 KEP63558.1 - 3.5 7.4 0.2 9.9 5.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.20 KEP63559.1 - 1.3e-43 149.0 0.0 1.2e-19 70.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63559.1 - 1.5e-19 70.1 0.0 1.7e-08 33.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 KEP63559.1 - 0.00025 20.1 0.0 0.00047 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEP63559.1 - 0.57 9.0 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 KEP63559.1 - 2.7 6.6 0.0 3.9 6.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ThiF PF00899.16 KEP63560.1 - 9.7e-31 106.4 0.0 1.5e-21 76.6 0.1 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KEP63560.1 - 4.3e-25 87.0 0.3 8.7e-25 86.0 0.2 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEP63560.1 - 2.2e-18 65.3 0.4 6.1e-18 63.9 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KEP63560.1 - 2.8e-18 65.8 0.0 7e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 KEP63560.1 - 0.0016 18.7 0.0 0.03 14.5 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KEP63560.1 - 0.003 17.6 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase zf-C2H2 PF00096.21 KEP63565.1 - 4.4e-23 80.1 66.1 6.1e-05 23.1 2.6 8.3 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEP63565.1 - 1.4e-18 65.7 62.1 0.00038 20.5 0.9 8.6 8 0 0 8 8 8 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEP63565.1 - 1.5e-07 31.3 60.1 0.001 19.2 2.3 9.8 9 2 0 9 9 9 5 Zinc-finger double domain zf-C2H2_6 PF13912.1 KEP63565.1 - 7.6e-07 28.8 31.5 0.0042 16.9 0.5 6.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-met PF12874.2 KEP63565.1 - 0.001 19.1 14.8 0.78 10.0 0.3 5.5 5 0 0 5 5 5 2 Zinc-finger of C2H2 type GAGA PF09237.6 KEP63565.1 - 0.0048 16.4 3.4 0.0048 16.4 2.3 5.4 5 2 2 7 7 7 1 GAGA factor zf-C2H2_jaz PF12171.3 KEP63565.1 - 0.033 14.3 27.1 0.23 11.6 0.1 6.4 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_4 PF13717.1 KEP63565.1 - 3.8 7.2 21.5 14 5.5 0.5 5.7 5 0 0 5 5 5 0 zinc-ribbon domain FYDLN_acid PF09538.5 KEP63565.1 - 3.9 8.0 12.8 6.1 7.4 0.1 5.0 3 3 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_5 PF13719.1 KEP63565.1 - 8.3 6.0 23.1 9.5 5.8 0.6 5.6 4 1 0 4 4 4 0 zinc-ribbon domain SAG PF04092.8 KEP63566.1 - 4.1e-10 40.1 0.0 6.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 SRS domain Fibrillarin PF01269.12 KEP63567.1 - 7.2e-112 371.8 0.0 8.5e-112 371.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KEP63567.1 - 0.00021 20.8 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KEP63567.1 - 0.01 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 KEP63567.1 - 0.059 12.2 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.2 KEP63567.1 - 0.084 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KEP63567.1 - 0.11 12.0 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 3HCDH PF00725.17 KEP63568.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4131 PF13567.1 KEP63568.1 - 4.4 6.6 8.0 91 2.3 5.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Mpp10 PF04006.7 KEP63569.1 - 1.6e-42 145.7 106.9 5.9e-33 114.1 7.3 4.0 2 1 1 3 3 3 2 Mpp10 protein WD40 PF00400.27 KEP63570.1 - 4.3e-07 29.5 7.8 0.29 11.1 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat SRA1 PF07304.6 KEP63570.1 - 0.0023 17.6 0.0 0.0023 17.6 0.0 2.3 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 KEP63570.1 - 0.0095 15.7 0.2 0.0095 15.7 0.2 1.6 2 0 0 2 2 2 1 Prp18 domain tRNA_m1G_MT PF01746.16 KEP63571.1 - 1.2e-23 83.6 0.1 2.9e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase SR-25 PF10500.4 KEP63571.1 - 0.0076 15.7 8.8 0.021 14.2 6.1 1.7 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dodecin PF07311.7 KEP63571.1 - 0.47 10.5 2.2 28 4.8 0.5 2.4 2 0 0 2 2 2 0 Dodecin Aldedh PF00171.17 KEP63574.1 - 8.1e-120 400.2 0.0 1e-119 399.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEP63574.1 - 0.00087 18.1 0.0 0.02 13.6 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Agro_virD5 PF04730.7 KEP63575.1 - 0.077 11.0 0.0 0.085 10.8 0.0 1.2 1 0 0 1 1 1 0 Agrobacterium VirD5 protein cNMP_binding PF00027.24 KEP63576.1 - 3e-69 228.8 0.9 2.9e-20 71.8 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase PF00069.20 KEP63576.1 - 6.7e-68 228.6 0.0 1.1e-67 227.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63576.1 - 1.9e-31 109.1 0.0 3.7e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP63576.1 - 7.3e-08 31.7 0.0 1.9e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Cupin_2 PF07883.6 KEP63576.1 - 6.6e-05 22.3 0.1 5.1 6.6 0.0 4.3 4 0 0 4 4 4 2 Cupin domain Kdo PF06293.9 KEP63576.1 - 0.0015 17.6 0.0 0.0039 16.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP63576.1 - 0.012 15.3 0.0 0.038 13.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEP63576.1 - 0.12 11.2 0.0 0.23 10.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DSPc PF00782.15 KEP63577.1 - 3.3e-16 59.0 0.0 5.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain V-SNARE_C PF12352.3 KEP63578.1 - 8.2e-08 32.2 0.5 1.6e-07 31.2 0.4 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 KEP63578.1 - 0.00016 21.7 2.6 0.043 13.9 0.1 3.2 3 0 0 3 3 3 2 Vesicle transport v-SNARE protein N-terminus Syntaxin PF00804.20 KEP63578.1 - 0.036 14.2 0.9 0.13 12.3 0.2 2.2 1 1 0 1 1 1 0 Syntaxin Exonuc_VII_S PF02609.11 KEP63578.1 - 0.95 9.2 4.3 0.97 9.2 0.2 2.7 4 0 0 4 4 4 0 Exonuclease VII small subunit Metallophos PF00149.23 KEP63579.1 - 4.7e-40 137.1 0.1 7.7e-40 136.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEP63579.1 - 0.022 14.6 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain cNMP_binding PF00027.24 KEP63580.1 - 2e-43 146.1 0.1 4e-22 77.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KEP63580.1 - 0.0025 17.1 0.0 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit PfkB PF00294.19 KEP63580.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 pfkB family carbohydrate kinase DUF4510 PF14971.1 KEP63580.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) HR1 PF02185.11 KEP63580.1 - 0.21 11.3 2.3 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat PTPLA PF04387.9 KEP63581.1 - 7.1e-44 149.1 12.0 1.2e-23 83.3 0.2 2.4 3 0 0 3 3 3 2 Protein tyrosine phosphatase-like protein, PTPLA EF-hand_7 PF13499.1 KEP63583.1 - 5e-05 23.3 0.0 0.00021 21.3 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEP63583.1 - 0.0059 15.8 0.1 0.028 13.7 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KEP63583.1 - 0.068 13.0 0.3 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 KEP63583.1 - 0.087 12.4 0.2 0.86 9.2 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain pair Glycos_trans_3N PF02885.12 KEP63583.1 - 0.12 11.9 0.3 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Prothymosin PF03247.9 KEP63584.1 - 0.094 12.8 14.4 0.19 11.9 10.0 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family CDC45 PF02724.9 KEP63584.1 - 1.5 6.7 12.1 2.1 6.2 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein BTB PF00651.26 KEP63585.1 - 5.4e-08 32.8 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2413 PF10310.4 KEP63585.1 - 0.22 10.2 9.7 0.71 8.6 6.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ycf1 PF05758.7 KEP63585.1 - 0.25 9.0 5.2 0.5 8.0 3.6 1.4 1 0 0 1 1 1 0 Ycf1 DnaJ PF00226.26 KEP63586.1 - 7.4e-26 89.6 1.2 1.5e-25 88.6 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEP63586.1 - 2.1e-22 78.8 0.2 2e-21 75.6 0.0 2.7 4 0 0 4 4 4 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEP63586.1 - 1.7e-13 50.3 16.1 3.5e-13 49.3 11.1 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEP63586.1 - 0.0013 18.4 4.9 0.1 12.2 0.2 2.5 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family TauE PF01925.14 KEP63588.1 - 1.2e-18 67.5 44.8 1.8e-10 40.7 5.7 3.2 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE DD_K PF12121.3 KEP63588.1 - 0.017 14.9 1.0 0.043 13.7 0.7 1.7 1 0 0 1 1 1 0 Dermaseptin Ycf1 PF05758.7 KEP63589.1 - 2.7 5.5 2.9 4.1 4.9 2.0 1.2 1 0 0 1 1 1 0 Ycf1 PWI PF01480.12 KEP63592.1 - 3.7e-25 87.8 0.0 5.8e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.13 KEP63592.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain DUF755 PF05501.6 KEP63593.1 - 0.081 12.9 0.3 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SURF1 PF02104.10 KEP63594.1 - 2e-24 86.6 5.8 1.3e-18 67.6 3.0 3.1 2 1 0 2 2 2 2 SURF1 family PepSY_TM_2 PF13703.1 KEP63594.1 - 0.24 11.6 1.4 18 5.5 0.3 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix Mak10 PF04112.8 KEP63595.1 - 0.00016 20.9 0.0 0.46 9.6 0.0 2.7 2 0 0 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ufm1 PF03671.9 KEP63596.1 - 3e-40 135.8 0.3 3.4e-40 135.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein zf-CCCH PF00642.19 KEP63597.1 - 2.1e-07 30.4 15.0 9.8e-06 25.1 0.5 4.0 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 KEP63597.1 - 0.38 10.3 3.2 8.1 6.1 0.1 2.8 2 0 0 2 2 2 0 LRV protein FeS4 cluster UCH PF00443.24 KEP63598.1 - 3.2e-35 121.5 0.0 4.9e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP63598.1 - 3.3e-05 23.4 2.9 0.072 12.5 0.4 2.6 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ion_trans PF00520.26 KEP63599.1 - 3.5e-20 72.1 22.6 3.4e-17 62.3 5.6 2.6 2 0 0 2 2 2 2 Ion transport protein RRM_5 PF13893.1 KEP63601.1 - 0.0051 16.6 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HD PF01966.17 KEP63602.1 - 3.1e-09 36.8 0.0 6.8e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 HD domain U3snoRNP10 PF12397.3 KEP63604.1 - 2.5e-28 98.4 3.0 2.5e-28 98.4 2.1 4.9 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 BUD22 PF09073.5 KEP63607.1 - 9.6e-05 21.6 26.0 0.00012 21.3 18.0 1.2 1 0 0 1 1 1 1 BUD22 Macoilin PF09726.4 KEP63607.1 - 0.069 11.4 20.3 0.07 11.3 14.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Y_phosphatase3 PF13350.1 KEP63607.1 - 0.075 13.2 0.0 0.075 13.2 0.0 2.2 2 1 0 2 2 2 0 Tyrosine phosphatase family PPP4R2 PF09184.6 KEP63607.1 - 0.22 11.0 19.4 0.27 10.7 13.5 1.1 1 0 0 1 1 1 0 PPP4R2 SRP-alpha_N PF04086.8 KEP63607.1 - 0.23 10.8 29.0 0.31 10.4 20.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAM60A PF15396.1 KEP63607.1 - 0.28 10.9 28.9 0.07 12.8 17.8 1.6 2 0 0 2 2 2 0 Protein Family FAM60A Apt1 PF10351.4 KEP63607.1 - 0.59 8.9 28.2 0.7 8.6 19.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.7 KEP63607.1 - 0.79 8.0 37.6 1.3 7.3 26.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 KEP63607.1 - 4 5.7 40.4 4.9 5.4 28.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 KEP63607.1 - 5 4.6 20.8 5.3 4.5 14.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0560 PF10577.4 KEP63607.1 - 5.1 5.2 21.8 6.1 4.9 15.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3827 PF12877.2 KEP63607.1 - 6.6 4.7 25.8 8.6 4.3 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Rtf2 PF04641.7 KEP63607.1 - 7.9 5.5 25.3 16 4.6 17.5 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Peptidase_S64 PF08192.6 KEP63607.1 - 9.7 4.3 15.2 10 4.2 10.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF2443 PF10398.4 KEP63609.1 - 1.4 8.7 0.0 3.1 7.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) ATP-synt_F PF01990.12 KEP63611.1 - 2.9e-30 104.5 0.2 3.5e-30 104.2 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit RC-P840_PscD PF10657.4 KEP63611.1 - 0.07 12.9 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD DUF359 PF04019.7 KEP63611.1 - 0.084 12.2 0.4 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF359) AP2 PF00847.15 KEP63612.1 - 1.8e-07 31.2 0.3 1.8e-07 31.2 0.2 2.3 3 0 0 3 3 3 1 AP2 domain DUF11 PF01345.13 KEP63614.1 - 0.14 12.2 0.7 0.37 10.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF11 WD40 PF00400.27 KEP63615.1 - 5.9e-11 41.8 4.4 1.5e-06 27.8 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat AP2 PF00847.15 KEP63616.1 - 2.9e-12 46.5 7.3 5e-07 29.7 1.1 2.7 2 0 0 2 2 2 2 AP2 domain DUF106 PF01956.11 KEP63617.1 - 2.5e-16 59.6 0.0 1.2e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 Integral membrane protein DUF106 FH2 PF02181.18 KEP63617.1 - 0.095 11.5 0.3 0.13 11.0 0.2 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain AATF-Che1 PF13339.1 KEP63617.1 - 0.11 12.6 1.4 1.1 9.4 0.2 2.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF1049 PF06305.6 KEP63617.1 - 1.4 8.4 0.0 1.4 8.4 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) WD40 PF00400.27 KEP63618.1 - 1.2e-56 186.6 15.7 6.6e-09 35.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEP63618.1 - 0.0058 15.4 0.3 0.77 8.4 0.0 2.1 1 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 KEP63618.1 - 0.02 13.0 0.2 0.5 8.4 0.0 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.7 KEP63618.1 - 0.12 12.1 0.5 24 4.7 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 KEP63618.1 - 0.18 12.1 1.4 2.9 8.3 0.0 3.6 5 0 0 5 5 5 0 PQQ-like domain zf-MYND PF01753.13 KEP63619.1 - 1.8e-12 46.9 8.7 2.4e-12 46.4 5.5 1.7 1 1 0 1 1 1 1 MYND finger Rib_recp_KP_reg PF05104.7 KEP63619.1 - 0.018 15.5 1.7 0.029 14.8 1.2 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region DUF3846 PF12957.2 KEP63619.1 - 0.044 13.5 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Ecl1 PF12855.2 KEP63619.1 - 0.073 12.3 0.1 0.17 11.1 0.1 1.6 1 0 0 1 1 1 0 Life-span regulatory factor zf-ribbon_3 PF13248.1 KEP63619.1 - 0.6 9.3 6.6 1.7 7.9 4.6 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-Mss51 PF13824.1 KEP63619.1 - 1 9.2 7.1 2.5 8.0 4.9 1.7 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4131 PF13567.1 KEP63621.1 - 0.11 11.9 0.4 0.15 11.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RseC_MucC PF04246.7 KEP63621.1 - 0.44 10.1 1.5 0.84 9.2 1.0 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC ECH PF00378.15 KEP63622.1 - 7.6e-38 130.0 0.0 1.4e-30 106.2 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Slu7 PF11708.3 KEP63623.1 - 2.3e-69 233.7 20.6 2.3e-69 233.7 14.3 2.6 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KEP63623.1 - 1.1 8.9 6.3 0.14 11.8 0.3 2.4 3 0 0 3 3 3 0 Zinc knuckle Apyrase PF06079.6 KEP63624.1 - 1.2e-95 320.0 0.0 1.5e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Apyrase CRAL_TRIO PF00650.15 KEP63625.1 - 1.6e-24 86.2 0.0 2.1e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain DUF3080 PF11279.3 KEP63626.1 - 0.01 15.0 0.1 0.012 14.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3080) Tn7_Tnp_TnsA_C PF08721.6 KEP63626.1 - 0.05 13.6 0.6 0.23 11.5 0.0 2.2 2 1 0 2 2 2 0 TnsA endonuclease C terminal Sigma70_ner PF04546.8 KEP63626.1 - 0.054 13.1 5.4 0.078 12.5 3.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region AAA-ATPase_like PF09820.4 KEP63626.1 - 0.057 12.5 0.6 0.078 12.1 0.4 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase YlbD_coat PF14071.1 KEP63626.1 - 0.69 9.9 6.0 0.6 10.1 0.8 2.2 1 1 1 2 2 2 0 Putative coat protein DUF3042 PF11240.3 KEP63627.1 - 0.086 12.6 4.2 0.17 11.7 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Thioredoxin_2 PF13098.1 KEP63628.1 - 0.046 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain ORC5_C PF14630.1 KEP63631.1 - 4.7e-15 55.7 0.0 2.9e-14 53.1 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.1 KEP63631.1 - 0.0024 18.0 0.1 3.5 7.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain 2OG-FeII_Oxy_3 PF13640.1 KEP63632.1 - 1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEP63632.1 - 2.2e-07 30.3 0.0 4.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEP63632.1 - 1.4e-05 25.2 0.0 2.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Folate_rec PF03024.9 KEP63633.1 - 0.063 12.9 4.3 0.045 13.3 1.8 1.4 1 1 0 1 1 1 0 Folate receptor family HSP20 PF00011.16 KEP63634.1 - 7.6e-16 57.8 0.0 1.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family V_ATPase_I PF01496.14 KEP63636.1 - 6.7e-174 579.7 0.0 7.7e-174 579.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HSBP1 PF06825.7 KEP63636.1 - 0.081 12.5 0.1 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Evr1_Alr PF04777.8 KEP63637.1 - 1e-11 44.5 0.2 1.6e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Cwf_Cwc_15 PF04889.7 KEP63638.1 - 3.5 7.2 8.1 4 7.0 2.3 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MRP-S26 PF14943.1 KEP63639.1 - 4.8 6.7 8.2 1.6 8.2 1.7 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 IPP-2 PF04979.9 KEP63640.1 - 1.1e-17 64.4 4.4 1.7e-17 63.9 3.1 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Methyltransf_10 PF05971.7 KEP63641.1 - 2e-67 227.4 3.5 2.8e-43 148.1 0.0 4.0 1 1 2 3 3 3 3 Protein of unknown function (DUF890) MTS PF05175.9 KEP63641.1 - 4e-06 26.2 0.0 6.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KEP63641.1 - 0.00014 22.4 0.0 0.00029 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP63641.1 - 0.00037 20.5 0.0 0.00073 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP63641.1 - 0.0075 16.6 0.0 0.032 14.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP63641.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEP63641.1 - 0.032 14.6 0.0 0.086 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Myf5 PF12232.3 KEP63641.1 - 0.036 14.6 2.3 0.17 12.5 1.6 2.1 1 0 0 1 1 1 0 Myogenic determination factor 5 UPF0020 PF01170.13 KEP63641.1 - 0.041 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MBOAT PF03062.14 KEP63643.1 - 3.1e-18 65.9 35.7 1e-17 64.3 24.8 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KEP63643.1 - 6.3e-05 22.9 4.4 6.3e-05 22.9 3.0 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family AD PF09793.4 KEP63644.1 - 7.3e-20 70.6 0.0 1.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain LSM PF01423.17 KEP63644.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 LSM domain SM-ATX PF14438.1 KEP63644.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_S3Ae PF01015.13 KEP63645.1 - 3.7e-82 274.3 0.5 4.6e-82 274.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Bul1_C PF04426.7 KEP63645.1 - 0.045 12.9 0.2 0.061 12.5 0.1 1.2 1 0 0 1 1 1 0 Bul1 C terminus TPT PF03151.11 KEP63647.1 - 1.3e-19 70.3 12.6 1.3e-19 70.3 8.8 2.8 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KEP63647.1 - 0.039 13.9 41.9 0.48 10.4 11.0 3.0 2 1 1 3 3 3 0 EamA-like transporter family PH PF00169.24 KEP63649.1 - 0.012 15.7 0.0 0.041 14.0 0.0 1.9 1 0 0 1 1 1 0 PH domain TPR_11 PF13414.1 KEP63650.1 - 1.5e-20 72.5 4.1 4.5e-11 42.2 0.7 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 KEP63650.1 - 2.2e-07 30.1 7.1 3e-05 23.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEP63650.1 - 2.1e-05 25.0 4.7 0.00047 20.7 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP63650.1 - 2.5e-05 23.8 13.8 0.0012 18.5 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEP63650.1 - 0.0006 19.8 1.2 0.011 15.8 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEP63650.1 - 0.009 15.8 0.1 0.041 13.7 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP63650.1 - 0.043 14.4 0.0 0.043 14.4 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2109 PF09882.4 KEP63651.1 - 0.034 14.0 3.9 0.063 13.2 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) DUF2663 PF10864.3 KEP63651.1 - 0.31 11.2 2.5 0.26 11.5 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Peptidase_M50B PF13398.1 KEP63651.1 - 0.94 8.8 10.4 2.2 7.6 2.1 2.1 1 1 1 2 2 2 0 Peptidase M50B-like DUF1212 PF06738.7 KEP63651.1 - 2 7.8 12.1 4 6.8 8.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) LHC PF00556.15 KEP63651.1 - 5.6 6.8 7.5 1.6 8.6 1.1 2.6 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit PTS_2-RNA PF01885.11 KEP63653.1 - 7.6e-51 172.0 0.0 1.1e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DSPc PF00782.15 KEP63655.1 - 5e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEP63655.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase NuA4 PF09340.5 KEP63656.1 - 8.7e-20 70.1 0.0 1.8e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Patatin PF01734.17 KEP63657.1 - 2.3e-12 47.2 0.6 2.5e-10 40.6 0.2 2.7 2 1 0 2 2 2 2 Patatin-like phospholipase GCS PF03074.11 KEP63658.1 - 4.4e-90 302.4 0.0 3e-47 161.4 0.0 3.2 3 0 0 3 3 3 3 Glutamate-cysteine ligase AMP-binding PF00501.23 KEP63659.1 - 3.9e-79 265.9 0.0 5e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEP63659.1 - 3.5e-18 66.2 1.0 9.6e-18 64.9 0.4 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 KEP63659.1 - 0.073 12.7 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) OmpH PF03938.9 KEP63660.1 - 0.43 10.4 7.1 1.1 9.1 4.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Latarcin PF10279.4 KEP63661.1 - 0.91 9.7 4.6 2.7 8.2 0.4 2.5 1 1 1 2 2 2 0 Latarcin precursor DUF883 PF05957.8 KEP63661.1 - 1.8 9.0 9.0 1.7 9.0 0.5 3.0 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.1 KEP63661.1 - 2.9 8.0 5.7 3 7.9 1.7 2.9 2 1 0 2 2 2 0 MT0933-like antitoxin protein FAD_binding_3 PF01494.14 KEP63662.1 - 1.6e-44 152.3 0.5 1.2e-16 60.7 0.0 4.5 4 0 0 4 4 4 4 FAD binding domain Pyr_redox PF00070.22 KEP63662.1 - 0.0094 16.3 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEP63662.1 - 0.01 14.7 0.0 0.02 13.7 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 KEP63662.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 KEP63662.1 - 0.028 14.4 0.0 0.076 13.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain YycC PF14174.1 KEP63662.1 - 0.081 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 YycC-like protein SUV3_C PF12513.3 KEP63663.1 - 2.4e-13 49.3 0.0 5.8e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KEP63663.1 - 1.9e-07 30.8 0.0 0.00013 21.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Zot PF05707.7 KEP63663.1 - 0.035 13.5 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Brix PF04427.13 KEP63664.1 - 1.6e-27 96.3 0.0 1.2e-26 93.5 0.0 2.1 1 1 0 1 1 1 1 Brix domain UL11 PF11094.3 KEP63664.1 - 0.063 13.1 0.3 7.1 6.5 0.0 2.9 3 0 0 3 3 3 0 Membrane-associated tegument protein zf-RING_2 PF13639.1 KEP63665.1 - 7.2e-07 28.9 2.0 7.2e-07 28.9 1.4 4.4 5 0 0 5 5 3 1 Ring finger domain zf-rbx1 PF12678.2 KEP63665.1 - 0.00041 20.3 0.4 0.00041 20.3 0.3 2.9 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP63665.1 - 0.0011 18.5 0.6 0.0011 18.5 0.4 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP63665.1 - 0.0014 18.5 1.4 0.0014 18.5 0.9 4.2 5 0 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-ZPR1 PF03367.8 KEP63665.1 - 0.0015 17.6 2.1 0.0032 16.6 1.5 1.6 1 0 0 1 1 1 1 ZPR1 zinc-finger domain HAUS-augmin3 PF14932.1 KEP63665.1 - 0.0087 15.2 13.8 0.016 14.4 9.6 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 zf-UBP PF02148.14 KEP63665.1 - 0.016 15.3 0.7 0.016 15.3 0.5 4.8 4 2 0 4 4 2 0 Zn-finger in ubiquitin-hydrolases and other protein IncA PF04156.9 KEP63665.1 - 0.02 14.5 13.7 0.06 12.9 9.5 1.8 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 KEP63665.1 - 0.031 14.5 7.1 0.015 15.5 2.9 1.9 1 1 0 1 1 1 0 Snapin/Pallidin BRAP2 PF07576.7 KEP63665.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 Troponin PF00992.15 KEP63665.1 - 0.11 12.5 14.0 0.34 10.9 9.7 1.8 1 0 0 1 1 1 0 Troponin DUF972 PF06156.8 KEP63665.1 - 0.34 11.2 10.4 1.2 9.5 7.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) CDC37_N PF03234.9 KEP63665.1 - 0.53 10.5 9.3 0.98 9.7 6.5 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding FUSC PF04632.7 KEP63665.1 - 0.96 7.7 9.4 1.9 6.8 6.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bap31 PF05529.7 KEP63665.1 - 1.1 8.6 6.9 2.3 7.6 4.8 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF445 PF04286.7 KEP63665.1 - 1.2 8.5 7.4 1.8 7.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Mnd1 PF03962.10 KEP63665.1 - 1.4 8.5 10.8 3.6 7.2 7.5 1.6 1 0 0 1 1 1 0 Mnd1 family HlyD PF00529.15 KEP63665.1 - 1.9 7.7 21.9 3.5 6.8 15.2 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF342 PF03961.8 KEP63665.1 - 2.1 6.6 7.2 3.3 6.0 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FemAB PF02388.11 KEP63665.1 - 2.6 6.6 5.7 4.7 5.7 4.0 1.4 1 0 0 1 1 1 0 FemAB family V_ATPase_I PF01496.14 KEP63665.1 - 2.6 5.7 3.8 4.3 5.0 2.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4559 PF15112.1 KEP63665.1 - 3.3 6.8 7.6 5.6 6.0 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF607 PF04678.8 KEP63665.1 - 5.4 6.8 6.6 12 5.8 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF607 HAUS6_N PF14661.1 KEP63665.1 - 5.6 6.2 11.9 11 5.2 8.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Bacillus_HBL PF05791.6 KEP63667.1 - 0.0029 17.0 4.6 0.0029 17.0 3.2 5.3 3 2 3 6 6 6 1 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.6 KEP63667.1 - 0.085 12.7 0.0 0.085 12.7 0.0 6.1 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) SNF2_N PF00176.18 KEP63668.1 - 8.7e-63 211.8 0.0 1.2e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP63668.1 - 5e-13 48.7 0.0 9.9e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP63668.1 - 1.3e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEP63668.1 - 2.7e-07 30.5 0.0 6.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KEP63668.1 - 1.2e-06 27.5 0.0 3.3e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.4 KEP63668.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SPX PF03105.14 KEP63669.1 - 0.03 14.1 29.6 7.5 6.2 14.9 3.3 1 1 0 2 2 2 0 SPX domain DUF2285 PF10074.4 KEP63669.1 - 0.043 14.1 0.2 0.043 14.1 0.2 3.6 3 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2285) Reo_sigmaC PF04582.7 KEP63669.1 - 0.067 12.3 0.3 0.13 11.4 0.1 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KEP63669.1 - 0.56 10.5 6.7 0.99 9.7 0.8 3.8 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein SUKH-4 PF14435.1 KEP63669.1 - 2 8.0 9.1 12 5.6 1.9 2.9 2 0 0 2 2 2 0 SUKH-4 immunity protein Baculo_PEP_C PF04513.7 KEP63669.1 - 5 6.9 7.4 31 4.3 0.1 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.7 KEP63669.1 - 8.2 6.0 13.3 14 5.3 0.3 4.4 5 0 0 5 5 5 0 Heat shock factor binding protein 1 Muted PF14942.1 KEP63670.1 - 0.029 14.2 10.1 0.053 13.3 7.0 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein RPW8 PF05659.6 KEP63670.1 - 0.047 13.2 0.7 0.08 12.4 0.5 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 APG6 PF04111.7 KEP63670.1 - 0.34 9.9 13.3 0.47 9.4 9.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 KEP63670.1 - 0.68 8.8 12.7 0.96 8.3 8.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 KEP63670.1 - 0.76 9.8 9.4 0.57 10.2 5.2 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 KEP63670.1 - 3.8 5.8 6.7 5.3 5.3 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 KEP63670.1 - 5.7 4.6 5.2 7.4 4.2 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KEP63670.1 - 8.1 6.0 13.5 6.7 6.3 8.0 1.8 1 1 1 2 2 2 0 Mnd1 family Thioredoxin_8 PF13905.1 KEP63672.1 - 2.9e-22 78.5 0.0 4.1e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KEP63672.1 - 0.00034 20.2 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEP63672.1 - 0.0028 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin PROCN PF08083.6 KEP63672.1 - 0.025 13.0 0.0 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain Thioredoxin_2 PF13098.1 KEP63672.1 - 0.028 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain PAN_1 PF00024.21 KEP63673.1 - 5.3e-23 80.5 27.8 9.6e-08 31.6 0.2 4.2 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.1 KEP63673.1 - 3.8e-14 52.1 18.3 0.0012 18.4 1.9 4.6 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.6 KEP63673.1 - 2.3e-05 24.1 19.3 0.1 12.4 0.5 4.3 4 0 0 4 4 4 4 PAN-like domain PAN_3 PF08277.7 KEP63673.1 - 4.4e-05 23.0 10.9 0.83 9.3 0.0 4.2 4 0 0 4 4 4 3 PAN-like domain DUF2020 PF09449.5 KEP63673.1 - 0.14 11.8 0.1 0.28 10.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2020) RTC PF01137.16 KEP63674.1 - 2.1e-48 164.1 0.0 4.2e-48 163.0 0.0 1.4 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KEP63674.1 - 1.2e-17 63.7 4.0 2.8e-16 59.4 0.2 2.4 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain WD40 PF00400.27 KEP63675.1 - 2.8e-45 150.6 15.4 9e-09 34.8 0.0 10.9 11 0 0 11 11 11 8 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEP63675.1 - 0.00094 18.0 0.2 1.2 7.7 0.0 3.8 4 0 0 4 4 4 2 Nup133 N terminal like Utp12 PF04003.7 KEP63675.1 - 0.0081 16.0 1.5 0.51 10.2 0.1 2.4 2 0 0 2 2 2 2 Dip2/Utp12 Family Nup160 PF11715.3 KEP63675.1 - 0.04 12.0 6.0 0.13 10.3 0.1 3.5 4 1 1 5 5 5 0 Nucleoporin Nup120/160 zf-CW PF07496.10 KEP63676.1 - 3e-32 110.0 41.1 5.3e-12 45.2 4.9 3.5 3 0 0 3 3 3 3 CW-type Zinc Finger zinc_ribbon_5 PF13719.1 KEP63676.1 - 0.13 11.8 4.5 16 5.1 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KEP63676.1 - 0.39 10.4 3.6 45 3.8 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain RNase_T PF00929.19 KEP63677.1 - 1.3e-18 67.8 0.0 2.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.1 KEP63677.1 - 1.6e-11 44.2 0.0 2.5e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ldh_1_N PF00056.18 KEP63678.1 - 4.1e-36 123.9 0.1 6.2e-36 123.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEP63678.1 - 8.4e-34 116.7 0.0 1.5e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 KEP63678.1 - 0.0001 21.6 0.5 0.01 15.1 0.2 2.5 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.14 KEP63678.1 - 0.0064 15.2 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 KEP63678.1 - 0.0091 15.3 1.1 0.03 13.6 0.7 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KEP63678.1 - 0.066 12.8 0.3 0.16 11.5 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PP2C PF00481.16 KEP63679.1 - 1.6e-60 204.6 2.2 5.8e-55 186.4 0.1 3.5 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KEP63679.1 - 0.0064 16.2 0.0 0.061 13.0 0.0 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) RR_TM4-6 PF06459.7 KEP63679.1 - 6.7 6.5 16.5 15 5.3 11.4 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 KEP63679.1 - 9.9 3.6 9.9 14 3.2 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Exo_endo_phos PF03372.18 KEP63682.1 - 6.4e-08 32.8 0.0 1.3e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S3_C PF00189.15 KEP63683.1 - 7.9e-16 58.0 0.3 1.5e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KEP63683.1 - 1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 KH domain Gal_Lectin PF02140.13 KEP63684.1 - 9.9e-07 28.9 0.1 9.9e-07 28.9 0.1 2.9 3 0 0 3 3 3 1 Galactose binding lectin domain DUF4398 PF14346.1 KEP63685.1 - 0.0094 15.9 4.6 0.0094 15.9 3.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4398) His_Phos_2 PF00328.17 KEP63686.1 - 5.6e-05 22.6 0.4 1.1 8.5 0.0 3.5 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) Catalase PF00199.14 KEP63689.1 - 6.5e-190 630.7 0.9 7.7e-190 630.5 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KEP63689.1 - 5.8e-23 80.5 0.1 1.5e-22 79.2 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Cadherin_2 PF08266.7 KEP63689.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Cadherin-like zf-SNAP50_C PF12251.3 KEP63690.1 - 2.9e-30 105.1 0.4 1.1e-23 83.6 0.5 2.5 3 0 0 3 3 3 2 snRNA-activating protein of 50kDa MW C terminal SOG2 PF10428.4 KEP63690.1 - 8.2 4.9 27.6 0.0049 15.5 7.7 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Ribosomal_L7Ae PF01248.21 KEP63691.1 - 6.7e-25 86.4 0.1 7.7e-25 86.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.1 KEP63691.1 - 0.017 14.9 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase APP_Cu_bd PF12924.2 KEP63691.1 - 0.026 15.0 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD DPBB_1 PF03330.13 KEP63691.1 - 0.14 12.1 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SWIB PF02201.13 KEP63692.1 - 8.9e-11 41.3 0.0 1.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain SAM_2 PF07647.12 KEP63692.1 - 0.0025 17.6 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEP63692.1 - 0.0028 17.7 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CytochromB561_N PF09786.4 KEP63692.1 - 5.6 5.2 29.2 5 5.4 3.2 2.3 2 0 0 2 2 2 0 Cytochrome B561, N terminal TFIIA PF03153.8 KEP63693.1 - 1.6e-05 24.9 7.1 3.7e-05 23.7 4.9 1.7 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Sec7 PF01369.15 KEP63695.1 - 8.6e-62 208.1 0.0 1.4e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KEP63695.1 - 0.0002 20.8 0.0 0.37 10.1 0.0 2.6 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Totivirus_coat PF05518.6 KEP63696.1 - 0.089 10.6 1.5 0.11 10.2 1.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein PIG-S PF10510.4 KEP63697.1 - 1.2e-27 96.7 2.2 3.6e-15 55.6 0.1 3.6 3 1 0 3 3 3 3 Phosphatidylinositol-glycan biosynthesis class S protein BAR PF03114.13 KEP63697.1 - 4.1e-05 23.2 0.0 0.00013 21.5 0.0 1.8 1 1 0 1 1 1 1 BAR domain UBA PF00627.26 KEP63697.1 - 0.00042 20.0 0.1 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_2 PF13639.1 KEP63699.1 - 1.7e-13 50.1 11.0 4e-13 48.9 7.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP63699.1 - 1.6e-06 28.0 9.2 5.7e-06 26.3 6.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP63699.1 - 5.2e-06 26.0 8.4 1.1e-05 24.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP63699.1 - 1.1e-05 25.3 9.8 2.8e-05 24.0 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP63699.1 - 0.00016 21.2 8.2 0.00034 20.2 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 KEP63699.1 - 0.06 13.3 5.1 0.14 12.1 3.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KEP63699.1 - 0.14 12.1 11.0 0.42 10.6 7.6 1.8 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 KEP63699.1 - 0.3 10.9 6.9 1 9.2 4.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KEP63699.1 - 1.2 8.9 6.9 2.2 8.0 4.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Baculo_RING PF05883.6 KEP63699.1 - 7.2 6.4 5.9 2.7 7.8 1.7 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain ATG16 PF08614.6 KEP63700.1 - 1.6 8.5 73.4 0.38 10.5 9.2 4.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Tachylectin PF14517.1 KEP63702.1 - 2.4e-06 27.0 0.4 0.013 14.8 0.3 3.1 1 1 2 3 3 3 3 Tachylectin PSII_BNR PF14870.1 KEP63702.1 - 1.6e-05 24.0 1.6 3.7e-05 22.8 0.9 1.7 1 1 1 2 2 2 1 Photosynthesis system II assembly factor YCF48 Reg_prop PF07494.6 KEP63702.1 - 3.2e-05 23.4 4.2 1.2 9.4 0.0 4.6 5 0 0 5 5 5 3 Two component regulator propeller DUF221 PF02714.10 KEP63703.1 - 4.1e-43 147.4 14.7 5.8e-43 146.9 10.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEP63703.1 - 3.5e-06 26.6 1.7 3.5e-06 26.6 1.2 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Fer2_2 PF01799.15 KEP63703.1 - 0.0024 17.7 0.1 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 [2Fe-2S] binding domain RAP PF08373.5 KEP63705.1 - 7.7e-08 32.0 1.8 1.6e-07 30.9 0.1 2.3 3 0 0 3 3 3 1 RAP domain 3HCDH PF00725.17 KEP63706.1 - 3.2e-35 120.3 0.0 5.6e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.13 KEP63706.1 - 1.2e-34 119.5 0.1 2.3e-34 118.6 0.1 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NOA36 PF06524.7 KEP63707.1 - 0.062 12.5 2.3 0.077 12.2 1.6 1.3 1 0 0 1 1 1 0 NOA36 protein Motilin_ghrelin PF04644.7 KEP63708.1 - 2.7 7.8 5.9 6.6 6.6 4.1 1.7 1 0 0 1 1 1 0 Motilin/ghrelin Chorein_N PF12624.2 KEP63709.1 - 3.5e-07 29.7 0.0 7.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Na_H_antiporter PF03553.9 KEP63709.1 - 0.95 8.4 0.2 1.8 7.5 0.2 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter family DUF1162 PF06650.7 KEP63709.1 - 1.4 8.0 0.0 7.7 5.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1162) Peptidase_S58 PF03576.9 KEP63710.1 - 8.2e-22 77.8 12.0 9.2e-19 67.7 6.3 2.6 2 1 1 3 3 3 2 Peptidase family S58 Herpes_UL32 PF06070.6 KEP63710.1 - 0.66 8.3 2.4 0.93 7.8 1.7 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DnaJ PF00226.26 KEP63711.1 - 3.1e-15 55.6 0.9 1e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain Thioredoxin_6 PF13848.1 KEP63711.1 - 0.11 12.2 0.1 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain CDC50 PF03381.10 KEP63712.1 - 1.1e-41 142.8 0.0 1.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family TauE PF01925.14 KEP63712.1 - 0.1 12.0 1.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE Fib_alpha PF08702.5 KEP63714.1 - 0.00028 21.0 1.5 0.00034 20.7 1.0 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 KEP63714.1 - 0.0046 17.0 3.1 0.0088 16.1 2.2 1.4 1 0 0 1 1 1 1 Syntaxin DUF3585 PF12130.3 KEP63714.1 - 0.016 15.0 2.8 0.022 14.6 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) YkyA PF10368.4 KEP63714.1 - 0.046 13.0 2.1 0.057 12.7 1.5 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein SlyX PF04102.7 KEP63714.1 - 0.056 13.8 6.3 0.1 12.9 0.5 2.2 2 0 0 2 2 2 0 SlyX Tup_N PF08581.5 KEP63714.1 - 0.1 12.7 5.0 2.9 8.1 0.5 2.2 2 0 0 2 2 2 0 Tup N-terminal Filo_VP35 PF02097.10 KEP63714.1 - 0.17 11.0 1.2 0.22 10.6 0.8 1.1 1 0 0 1 1 1 0 Filoviridae VP35 TMPIT PF07851.8 KEP63714.1 - 0.56 9.2 2.9 0.73 8.8 2.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein TMCO5 PF14992.1 KEP63714.1 - 0.75 8.8 7.4 3.8 6.5 5.1 1.8 1 1 0 1 1 1 0 TMCO5 family XhlA PF10779.4 KEP63714.1 - 2.3 8.1 6.6 50 3.9 4.6 2.1 1 1 0 1 1 1 0 Haemolysin XhlA HR1 PF02185.11 KEP63714.1 - 2.5 7.9 9.2 13 5.5 6.2 2.0 1 1 1 2 2 2 0 Hr1 repeat Spc24 PF08286.6 KEP63714.1 - 3.7 7.2 7.5 2.7 7.7 0.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.1 KEP63714.1 - 4.4 7.7 6.1 2.2 8.7 1.1 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PP2C PF00481.16 KEP63716.1 - 1.1e-54 185.5 1.5 2.3e-28 99.2 0.0 3.7 4 0 0 4 4 4 3 Protein phosphatase 2C COX17 PF05051.8 KEP63720.1 - 0.098 12.6 0.8 0.098 12.6 0.5 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Fer4_6 PF12837.2 KEP63720.1 - 0.98 9.4 5.7 0.31 10.9 0.8 2.4 2 1 0 2 2 2 0 4Fe-4S binding domain Reg_prop PF07494.6 KEP63724.1 - 0.19 11.8 0.0 0.58 10.3 0.0 1.8 1 0 0 1 1 1 0 Two component regulator propeller PROCN PF08083.6 KEP63725.1 - 3.3e-217 720.7 6.6 5.2e-217 720.1 4.6 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KEP63725.1 - 1.7e-126 420.2 1.5 2.8e-126 419.4 1.0 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KEP63725.1 - 2.6e-92 306.4 1.6 5.1e-92 305.4 1.1 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KEP63725.1 - 1.1e-82 275.0 3.6 1.1e-82 275.0 2.5 2.2 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KEP63725.1 - 9.5e-69 229.2 0.1 2.2e-68 228.0 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 KEP63725.1 - 1.5e-50 170.0 0.0 3.2e-50 169.0 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 KEP63725.1 - 2.4e-44 149.1 0.4 6.9e-44 147.6 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 KEP63725.1 - 4.8e-07 29.5 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ThiF PF00899.16 KEP63729.1 - 2.6e-35 121.1 0.0 7.4e-35 119.7 0.0 1.7 1 1 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 KEP63729.1 - 0.0029 16.6 0.3 0.54 9.1 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 KEP63729.1 - 0.089 12.1 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 KEP63729.1 - 0.13 12.5 0.1 0.56 10.4 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KEP63729.1 - 0.17 10.8 0.3 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain zf-C3HC4_3 PF13920.1 KEP63730.1 - 1.9e-05 24.2 12.1 1.9e-05 24.2 8.4 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP63730.1 - 0.00017 21.5 15.9 0.00017 21.5 11.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP63730.1 - 0.0017 18.1 15.4 0.0017 18.1 10.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KEP63730.1 - 0.0057 16.2 12.7 0.0057 16.2 8.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KEP63730.1 - 5.1 6.7 15.4 2.8 7.5 6.2 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 adh_short PF00106.20 KEP63731.1 - 6.3e-12 45.7 0.1 1.1e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEP63731.1 - 0.00013 21.8 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2369 PF10179.4 KEP63731.1 - 0.0015 17.7 0.0 0.25 10.4 0.0 2.6 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2369) Eno-Rase_NADH_b PF12242.3 KEP63731.1 - 0.0065 16.2 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thioredoxin PF00085.15 KEP63732.1 - 3e-08 33.2 0.0 3.7e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin ATP-synt PF00231.14 KEP63733.1 - 1.1e-75 254.6 0.6 1.3e-75 254.4 0.4 1.0 1 0 0 1 1 1 1 ATP synthase Acyl-CoA_dh_1 PF00441.19 KEP63734.1 - 3.1e-30 105.2 2.4 4.8e-30 104.6 1.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEP63734.1 - 1e-19 69.7 0.1 2.2e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEP63734.1 - 1.8e-15 57.4 0.1 3.7e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEP63734.1 - 3.2e-08 33.9 0.2 5.7e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KEP63734.1 - 0.00026 21.2 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACP_syn_III_C PF08541.5 KEP63735.1 - 2.8e-38 129.7 0.1 1.9e-37 127.1 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KEP63735.1 - 8.2e-26 89.4 0.1 2.3e-25 88.0 0.1 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_C PF02797.10 KEP63735.1 - 6.9e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Thiolase_C PF02803.13 KEP63735.1 - 0.0045 16.4 0.0 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain DUF3265 PF11665.3 KEP63735.1 - 0.32 10.8 3.2 0.36 10.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) TPR_1 PF00515.23 KEP63737.1 - 1.2e-20 72.1 1.1 5.3e-06 25.8 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEP63737.1 - 1.7e-20 72.3 7.4 6.6e-12 44.9 0.1 4.1 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 KEP63737.1 - 1.6e-19 68.1 6.5 8.6e-05 22.1 0.0 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEP63737.1 - 3.4e-15 55.1 11.2 8e-05 22.9 0.6 6.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEP63737.1 - 3.1e-12 46.7 20.3 5.9e-07 29.9 0.4 5.0 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEP63737.1 - 1.7e-11 42.9 8.8 0.00016 21.2 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEP63737.1 - 1.1e-10 40.8 10.9 2.9e-05 23.9 0.0 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEP63737.1 - 8.5e-10 38.8 10.1 6.9e-06 26.3 0.4 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP63737.1 - 3.7e-09 35.6 0.0 0.066 13.0 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP63737.1 - 5.8e-09 35.7 12.9 1.4e-05 24.9 1.4 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP63737.1 - 1.5e-06 27.9 3.7 0.0037 17.0 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEP63737.1 - 0.0014 17.7 4.7 0.0014 17.7 3.3 3.4 4 1 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 KEP63737.1 - 0.0028 17.9 19.3 0.0047 17.2 0.1 4.3 4 1 0 4 4 4 2 Bacterial transcriptional activator domain Apc3 PF12895.2 KEP63737.1 - 0.003 17.6 0.9 0.66 10.1 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEP63737.1 - 0.29 11.6 9.2 9.6 6.9 0.1 5.1 6 1 0 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEP63737.1 - 0.72 9.8 18.7 0.47 10.4 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEP63737.1 - 8.2 7.1 17.7 6.8 7.4 0.0 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat PP2C PF00481.16 KEP63740.1 - 6.6e-36 123.9 0.0 9.1e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEP63740.1 - 3.8e-05 23.2 0.0 0.00036 19.9 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Dor1 PF04124.7 KEP63740.1 - 0.079 11.4 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family Bestrophin PF01062.16 KEP63741.1 - 9 5.1 7.1 29 3.4 4.9 1.8 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel AAA_11 PF13086.1 KEP63742.1 - 7.2e-52 176.3 6.2 3.9e-49 167.3 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KEP63742.1 - 5.7e-46 156.4 0.0 1.3e-27 96.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KEP63742.1 - 9e-11 41.7 6.9 1.4e-06 28.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KEP63742.1 - 1.2e-10 41.0 0.0 1.9e-09 37.1 0.0 3.2 2 1 0 2 2 2 1 Part of AAA domain DEAD PF00270.24 KEP63742.1 - 0.0016 17.9 0.0 0.0039 16.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C_2 PF13307.1 KEP63743.1 - 1.3e-39 135.8 0.0 3.5e-38 131.1 0.0 2.6 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEP63743.1 - 2.3e-23 82.4 1.1 4.7e-16 58.6 0.0 2.5 2 0 0 2 2 2 2 DEAD_2 DEAD PF00270.24 KEP63743.1 - 0.0015 18.0 0.0 0.034 13.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KEP63743.1 - 0.0017 18.2 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KEP63743.1 - 0.0046 16.6 0.2 0.019 14.7 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KEP63743.1 - 0.057 12.9 2.8 0.036 13.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KEP63743.1 - 0.76 8.9 0.1 1.5 7.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Tubulin PF00091.20 KEP63746.1 - 4.4e-66 222.7 0.0 7.2e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEP63746.1 - 1.3e-46 157.7 0.1 2.3e-46 156.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF1415 PF07209.7 KEP63746.1 - 0.049 13.3 0.1 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Macro PF01661.16 KEP63747.1 - 5.5e-09 35.9 0.0 3.4e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Macro domain IMCp PF12314.3 KEP63748.1 - 9.7e-30 102.5 40.4 9.7e-30 102.5 28.0 5.5 2 2 3 5 5 5 2 Inner membrane complex protein AAA_23 PF13476.1 KEP63748.1 - 0.13 12.5 10.8 0.23 11.7 7.5 1.4 1 0 0 1 1 1 0 AAA domain eIF3_subunit PF08597.5 KEP63748.1 - 0.9 9.0 14.8 89 2.5 11.5 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit IMCp PF12314.3 KEP63750.1 - 1.5e-29 101.9 98.2 3.1e-17 62.4 18.7 4.8 1 1 4 5 5 5 4 Inner membrane complex protein ATP-gua_Ptrans PF00217.14 KEP63752.1 - 3.2e-38 131.4 0.0 3.6e-21 75.5 0.0 4.3 3 2 0 3 3 3 3 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 KEP63752.1 - 0.014 15.5 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain HEAT_2 PF13646.1 KEP63753.1 - 2.9e-17 62.7 19.0 1.5e-07 31.5 0.1 7.8 6 3 2 8 8 8 6 HEAT repeats HEAT PF02985.17 KEP63753.1 - 2.5e-11 42.6 23.8 0.0073 16.3 0.0 10.1 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 KEP63753.1 - 3.5e-11 43.2 30.7 0.11 13.0 0.1 12.4 10 3 5 15 15 15 5 HEAT-like repeat Arm PF00514.18 KEP63753.1 - 2e-05 24.2 1.1 8 6.4 0.2 5.0 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 KEP63753.1 - 0.025 14.9 0.9 16 5.9 0.1 4.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 KEP63753.1 - 0.046 13.6 0.3 0.34 10.8 0.2 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain RICTOR_V PF14668.1 KEP63753.1 - 0.071 13.0 1.2 9.4 6.2 0.0 3.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 SGS PF05002.10 KEP63754.1 - 1.1e-27 95.6 2.3 1.9e-27 94.7 1.6 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KEP63754.1 - 4.1e-11 43.2 0.0 9.2e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 CS domain HEAT PF02985.17 KEP63755.1 - 1.9e-18 64.7 51.7 0.00081 19.2 0.0 20.2 21 0 0 21 21 21 5 HEAT repeat HEAT_EZ PF13513.1 KEP63755.1 - 5.4e-11 42.6 84.6 0.00045 20.6 0.2 19.9 21 3 6 27 27 23 7 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KEP63755.1 - 7.6e-10 39.0 0.0 2.6 8.4 0.0 7.8 6 2 2 9 9 9 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KEP63755.1 - 1.1e-08 33.9 4.2 0.0007 18.0 0.0 5.6 6 1 0 7 7 7 2 Adaptin N terminal region CLASP_N PF12348.3 KEP63755.1 - 3.3e-05 23.3 0.2 0.022 14.0 0.0 4.7 4 1 1 5 5 5 1 CLASP N terminal UME PF08064.8 KEP63755.1 - 5.8e-05 22.9 2.7 1 9.3 0.0 6.4 7 0 0 7 7 7 1 UME (NUC010) domain ParcG PF10274.4 KEP63755.1 - 0.0015 18.4 0.7 75 3.1 0.0 5.8 6 1 0 6 6 6 0 Parkin co-regulated protein MMS19_N PF14500.1 KEP63755.1 - 0.0026 17.0 0.0 2.3 7.4 0.0 4.5 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.4 KEP63755.1 - 0.0093 14.2 0.4 0.21 9.7 0.0 3.3 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KEP63755.1 - 0.11 12.2 0.0 1e+02 2.6 0.0 5.1 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 KEP63755.1 - 1.7 8.6 12.9 2.7 8.0 0.0 7.8 12 0 0 12 12 12 0 Rix1 complex component involved in 60S ribosome maturation ATP-synt_10 PF05176.9 KEP63758.1 - 0.00034 19.9 0.0 0.00057 19.2 0.0 1.3 1 0 0 1 1 1 1 ATP10 protein LsmAD PF06741.8 KEP63760.1 - 2.1e-14 53.3 0.1 3.4e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 KEP63760.1 - 8.3e-12 44.8 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain STT3 PF02516.9 KEP63761.1 - 9.2e-85 285.4 39.7 2.3e-84 284.1 27.5 1.6 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit BT1 PF03092.11 KEP63762.1 - 3.6e-75 253.3 10.7 5e-75 252.8 7.4 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 KEP63762.1 - 5.4e-16 58.2 30.6 5.4e-16 58.2 21.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GED PF02212.13 KEP63763.1 - 0.002 18.0 2.1 0.0047 16.7 1.4 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF3038 PF11237.3 KEP63763.1 - 0.05 13.3 2.0 0.12 12.1 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3038) Tubulin PF00091.20 KEP63765.1 - 5.8e-51 173.3 0.0 9.4e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEP63765.1 - 7.3e-28 97.1 0.1 1.8e-27 95.8 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain RNA_pol_Rpb4 PF03874.11 KEP63767.1 - 1.3e-17 63.8 0.1 1.5e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Patatin PF01734.17 KEP63768.1 - 7.8e-29 101.0 1.3 6.5e-28 98.0 0.9 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase SIS PF01380.17 KEP63770.1 - 1.1e-31 109.1 0.0 1.6e-18 66.5 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 KEP63770.1 - 1.2e-20 73.8 0.1 1.1e-19 70.6 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KEP63770.1 - 7e-16 58.0 0.0 8.1e-15 54.6 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KEP63770.1 - 1.9e-15 56.4 0.1 3.1e-12 45.8 0.0 2.4 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 KEP63770.1 - 2.5e-06 26.3 0.3 4.6e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II WD40 PF00400.27 KEP63771.1 - 1e-28 98.1 7.8 1.9e-09 37.0 0.7 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 KEP63771.1 - 0.013 15.7 2.8 1.5 9.1 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain PD40 PF07676.7 KEP63771.1 - 0.48 10.1 5.1 13 5.6 0.1 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Plasmodium_Vir PF05795.6 KEP63771.1 - 3.3 6.8 8.4 6 5.9 2.0 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Dynamin_N PF00350.18 KEP63774.1 - 1.7e-21 76.7 0.0 7e-21 74.7 0.0 1.9 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 KEP63774.1 - 1.4e-10 40.8 0.0 4.9e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 KEP63774.1 - 5.2e-10 39.3 1.4 1.4e-09 37.8 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP63774.1 - 1.1e-05 24.9 0.0 3.2e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KEP63774.1 - 0.00033 21.1 0.0 0.0073 16.8 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 KEP63774.1 - 0.0015 18.0 0.0 0.29 10.6 0.0 2.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 KEP63774.1 - 0.0015 18.4 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KEP63774.1 - 0.0017 17.8 0.0 0.032 13.6 0.0 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 KEP63774.1 - 0.0049 16.0 0.0 0.13 11.4 0.0 2.6 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KEP63774.1 - 0.069 13.2 0.1 0.34 11.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.13 KEP63774.1 - 0.098 11.9 0.0 11 5.2 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B MobB PF03205.9 KEP63774.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B STAG PF08514.6 KEP63775.1 - 0.11 12.2 0.0 0.11 12.2 0.0 3.5 2 1 0 2 2 2 0 STAG domain ArsA_ATPase PF02374.10 KEP63776.1 - 2.8e-93 312.3 0.0 6e-85 284.9 0.0 2.0 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 KEP63776.1 - 4.7e-15 55.5 0.0 1.5e-14 53.8 0.0 1.8 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KEP63776.1 - 1.4e-08 34.8 0.1 7.8e-08 32.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KEP63776.1 - 2.5e-06 26.8 0.0 4.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KEP63776.1 - 0.00011 21.6 0.3 0.0025 17.2 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KEP63776.1 - 0.0004 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KEP63776.1 - 0.0025 16.9 0.5 0.047 12.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 KEP63776.1 - 0.0042 16.0 1.1 0.085 11.7 0.0 2.5 3 0 0 3 3 3 1 Type II/IV secretion system protein MipZ PF09140.6 KEP63776.1 - 0.0044 16.1 0.1 0.048 12.7 0.1 2.2 1 1 1 2 2 2 1 ATPase MipZ YhjQ PF06564.7 KEP63776.1 - 0.0091 15.3 0.0 0.078 12.3 0.0 2.2 2 0 0 2 2 2 1 YhjQ protein NB-ARC PF00931.17 KEP63776.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 KEP63776.1 - 0.017 14.5 0.5 0.093 12.1 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEP63776.1 - 0.033 14.1 2.9 0.13 12.2 0.0 2.7 1 1 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 KEP63776.1 - 0.053 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.2 KEP63776.1 - 0.067 12.6 0.3 0.16 11.3 0.2 1.9 1 1 0 1 1 1 0 AAA-like domain AAA PF00004.24 KEP63776.1 - 0.14 12.3 0.1 1.8 8.7 0.0 2.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEP63776.1 - 0.17 12.7 0.0 0.59 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KEP63776.1 - 0.21 11.1 1.1 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 KEP63776.1 - 0.26 10.7 2.0 0.34 10.3 0.0 2.2 3 0 0 3 3 3 0 IstB-like ATP binding protein RAMP4 PF06624.7 KEP63777.1 - 0.012 15.1 1.3 0.014 14.8 0.0 1.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF4551 PF15087.1 KEP63777.1 - 0.038 12.3 0.3 0.66 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) SMC_N PF02463.14 KEP63778.1 - 1.4e-66 223.8 18.2 4.9e-66 222.1 12.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEP63778.1 - 7.4e-23 80.7 0.0 3.7e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEP63778.1 - 2.1e-16 60.7 1.7 2.5e-07 30.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KEP63778.1 - 4.6e-15 56.4 0.0 4.6e-15 56.4 0.0 7.6 2 2 3 6 6 6 1 AAA domain AAA_29 PF13555.1 KEP63778.1 - 8.9e-07 28.3 0.0 1.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KEP63778.1 - 0.0037 16.3 0.0 0.0037 16.3 0.0 4.0 4 1 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.22 KEP63778.1 - 0.0063 16.8 0.0 0.0063 16.8 0.0 5.7 4 2 1 5 5 5 1 ABC transporter Reo_sigmaC PF04582.7 KEP63778.1 - 0.049 12.8 24.6 0.12 11.5 3.0 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Lactamase_B_2 PF12706.2 KEP63780.1 - 1.7e-10 40.8 0.0 2.3e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEP63780.1 - 7.3e-08 32.2 0.0 7.2e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Draxin PF15550.1 KEP63780.1 - 0.18 11.3 2.7 0.14 11.7 0.2 1.8 2 0 0 2 2 2 0 Draxin Ribosomal_S25 PF03297.10 KEP63781.1 - 7.3e-44 148.1 3.8 8.1e-44 147.9 2.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 KEP63781.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 KEP63781.1 - 0.028 14.5 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Fe_dep_repress PF01325.14 KEP63781.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.16 KEP63781.1 - 0.039 13.3 0.1 0.089 12.2 0.0 1.7 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family MarR_2 PF12802.2 KEP63781.1 - 0.053 13.1 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 MarR family DUF4423 PF14394.1 KEP63781.1 - 0.061 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) TrmB PF01978.14 KEP63781.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF3516 PF12029.3 KEP63781.1 - 0.1 11.3 0.3 0.095 11.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) Peptidase_M28 PF04389.12 KEP63782.1 - 1.1e-09 38.2 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Ribosomal_S11 PF00411.14 KEP63784.1 - 0.00024 21.2 2.0 0.00024 21.2 1.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S11 Ribosomal_L18p PF00861.17 KEP63784.1 - 0.00026 21.1 0.9 0.00051 20.2 0.2 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family COPI_assoc PF08507.5 KEP63785.1 - 1.3e-14 54.0 12.1 1.7e-14 53.6 8.4 1.1 1 0 0 1 1 1 1 COPI associated protein HAP PF03866.8 KEP63785.1 - 0.83 9.4 8.3 0.056 13.2 1.1 2.0 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) DUF4229 PF14012.1 KEP63785.1 - 9.7 6.1 9.1 0.25 11.2 0.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4229) UCR_Fe-S_N PF10399.4 KEP63786.1 - 1.2 8.3 4.8 1.2 8.3 1.3 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ribosomal_L38e PF01781.13 KEP63788.1 - 4.6e-28 96.7 0.2 6e-28 96.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family Pkinase PF00069.20 KEP63789.1 - 1.2e-36 126.2 0.0 1.8e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63789.1 - 1.9e-26 92.7 0.0 6.4e-26 90.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP63789.1 - 2.5e-05 24.1 0.0 7.2e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP63789.1 - 0.24 10.3 0.0 1.2 8.0 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Peptidase_S8 PF00082.17 KEP63790.1 - 4.5e-51 173.6 3.6 6.1e-51 173.2 2.5 1.1 1 0 0 1 1 1 1 Subtilase family Fumble PF03630.9 KEP63790.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fumble RNase_PH PF01138.16 KEP63793.1 - 1.4e-15 57.7 0.0 2.1e-14 53.9 0.0 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEP63793.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MttA_Hcf106 PF02416.11 KEP63793.1 - 0.066 12.3 0.7 0.15 11.2 0.5 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family Arv1 PF04161.8 KEP63794.1 - 3.5e-29 102.1 3.3 1.3e-24 87.3 0.1 2.7 3 0 0 3 3 3 2 Arv1-like family TF_Zn_Ribbon PF08271.7 KEP63796.1 - 0.02 14.2 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Elf1 PF05129.8 KEP63796.1 - 0.12 12.1 0.2 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like START PF01852.14 KEP63797.1 - 7.5e-22 77.6 0.4 1.4e-21 76.7 0.1 1.5 2 0 0 2 2 2 1 START domain FAD_syn PF06574.7 KEP63798.1 - 0.067 12.8 0.2 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD synthetase Myosin_head PF00063.16 KEP63799.1 - 2e-171 571.4 0.0 3.8e-171 570.5 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 KEP63799.1 - 0.00078 18.8 9.3 0.0084 15.6 0.5 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Prim-Pol PF09250.6 KEP63800.1 - 0.032 14.1 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal MMS1_N PF10433.4 KEP63801.1 - 2e-109 366.0 0.0 2.9e-109 365.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KEP63801.1 - 5e-82 275.5 0.0 5.6e-81 272.1 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region Adap_comp_sub PF00928.16 KEP63805.1 - 4.9e-76 255.3 0.0 6.2e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Abhydrolase_6 PF12697.2 KEP63807.1 - 3.8e-16 59.6 0.8 4.2e-15 56.2 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP63807.1 - 1.5e-08 34.5 0.0 6.5e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP63807.1 - 1.7e-06 27.8 0.0 4.2e-05 23.2 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KEP63807.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 KEP63807.1 - 0.0019 17.8 0.8 0.0019 17.8 0.5 1.8 2 0 0 2 2 2 1 Serine hydrolase Thioesterase PF00975.15 KEP63807.1 - 0.035 14.3 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_8 PF06259.7 KEP63807.1 - 0.31 10.5 1.5 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase PHD PF00628.24 KEP63808.1 - 2.8e-08 33.3 11.8 2.8e-08 33.3 8.2 2.0 2 0 0 2 2 2 1 PHD-finger MIP-T3 PF10243.4 KEP63808.1 - 0.078 11.4 31.8 0.11 10.9 22.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 T_cell_tran_alt PF15128.1 KEP63810.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 T-cell leukemia translocation-altered APG5 PF04106.7 KEP63811.1 - 1.8e-17 63.5 0.0 3.9e-08 33.0 0.0 3.5 3 0 0 3 3 3 3 Autophagy protein Apg5 PyocinActivator PF11112.3 KEP63812.1 - 0.084 12.7 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyocin activator protein PrtN Dynein_heavy PF03028.10 KEP63814.1 - 1.4e-171 572.1 0.0 2.3e-171 571.3 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEP63814.1 - 3.1e-84 282.8 0.0 9.6e-81 271.3 0.0 2.5 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEP63814.1 - 6.2e-79 264.7 0.0 1.3e-78 263.7 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEP63814.1 - 2.5e-45 154.5 0.0 5.4e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KEP63814.1 - 7.3e-42 143.3 5.6 1.6e-41 142.1 3.9 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 KEP63814.1 - 1.4e-33 115.6 0.0 1.3e-23 83.0 0.0 2.5 2 0 0 2 2 2 2 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KEP63814.1 - 7.6e-25 87.5 0.0 3e-24 85.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KEP63814.1 - 1.5e-20 73.3 0.0 1.2e-06 28.2 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.24 KEP63814.1 - 1.9e-11 44.2 0.0 0.0097 16.1 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP63814.1 - 4.1e-10 39.9 0.1 0.079 13.0 0.0 5.0 4 0 0 4 4 4 3 AAA domain Zeta_toxin PF06414.7 KEP63814.1 - 0.00015 20.9 0.7 1.7 7.6 0.0 3.7 3 0 0 3 3 3 2 Zeta toxin AAA_17 PF13207.1 KEP63814.1 - 0.00016 22.5 0.0 0.13 13.0 0.0 3.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KEP63814.1 - 0.0034 17.8 0.0 5.5 7.5 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein AAA_19 PF13245.1 KEP63814.1 - 0.0034 17.1 15.7 0.095 12.4 0.1 5.8 6 0 0 6 6 5 2 Part of AAA domain AAA_18 PF13238.1 KEP63814.1 - 0.013 15.8 0.0 7.4 6.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KEP63814.1 - 0.013 15.6 0.0 17 5.6 0.0 3.4 3 0 0 3 3 3 0 RNA helicase Glycos_transf_2 PF00535.21 KEP63814.1 - 0.034 13.8 0.0 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 AAA_28 PF13521.1 KEP63814.1 - 0.053 13.4 0.0 0.053 13.4 0.0 4.5 4 0 0 4 4 3 0 AAA domain DUF258 PF03193.11 KEP63814.1 - 0.13 11.4 0.1 25 4.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 KEP63814.1 - 0.17 11.5 1.9 5.5 6.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KEP63814.1 - 0.44 10.8 3.5 20 5.4 0.0 3.7 4 0 0 4 4 3 0 ABC transporter ATP_bind_1 PF03029.12 KEP63814.1 - 0.78 9.2 6.6 2.7 7.4 0.0 4.2 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein Methyltransf_31 PF13847.1 KEP63814.1 - 1.1 8.8 0.0 2.5 7.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MMR_HSR1 PF01926.18 KEP63814.1 - 3.4 7.6 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Exotox-A_bind PF09101.5 KEP63814.1 - 3.8 6.5 0.0 6.9 5.7 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A binding CDC50 PF03381.10 KEP63815.1 - 1.8e-41 142.1 0.0 2.4e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family AAA PF00004.24 KEP63816.1 - 1.5e-60 203.1 0.0 3.2e-41 140.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KEP63816.1 - 1.6e-11 43.9 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.1 KEP63816.1 - 6e-10 39.4 2.8 0.00052 20.0 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KEP63816.1 - 3.1e-09 37.6 2.2 0.0015 19.3 1.5 3.5 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEP63816.1 - 3e-08 33.8 0.0 0.0016 18.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KEP63816.1 - 6.5e-08 31.9 0.0 0.00015 20.9 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEP63816.1 - 8.5e-08 31.8 0.1 0.016 14.9 0.0 3.2 3 0 0 3 3 3 2 Part of AAA domain AAA_18 PF13238.1 KEP63816.1 - 9.3e-08 32.4 0.0 0.00045 20.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEP63816.1 - 3.7e-07 29.9 0.1 0.00052 19.7 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEP63816.1 - 4.5e-07 29.8 0.0 0.00043 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEP63816.1 - 1.8e-06 28.0 0.0 0.01 15.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 KEP63816.1 - 5.8e-06 25.2 0.0 0.084 11.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus NACHT PF05729.7 KEP63816.1 - 9.1e-06 25.4 0.0 0.2 11.3 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_33 PF13671.1 KEP63816.1 - 9.7e-06 25.5 0.0 0.0039 17.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEP63816.1 - 1.4e-05 24.6 2.5 0.074 12.4 0.1 3.3 3 1 1 4 4 3 2 AAA domain Zeta_toxin PF06414.7 KEP63816.1 - 5.7e-05 22.2 0.1 0.001 18.2 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KEP63816.1 - 0.0001 22.3 0.6 0.0094 15.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 KEP63816.1 - 0.00016 20.9 0.1 0.38 9.9 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 KEP63816.1 - 0.0002 21.0 0.2 0.067 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEP63816.1 - 0.00025 20.2 0.1 0.048 12.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KEP63816.1 - 0.00066 19.9 0.0 0.72 10.1 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.12 KEP63816.1 - 0.0023 16.8 0.1 0.18 10.6 0.0 2.5 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KEP63816.1 - 0.0036 16.9 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KEP63816.1 - 0.0045 15.8 0.1 2 7.2 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 KEP63816.1 - 0.0047 16.4 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KEP63816.1 - 0.0063 16.2 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_2 PF07724.9 KEP63816.1 - 0.011 15.6 0.0 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Bac_DnaA PF00308.13 KEP63816.1 - 0.015 14.9 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein Sigma54_activat PF00158.21 KEP63816.1 - 0.018 14.4 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 KEP63816.1 - 0.021 14.5 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 NTPase ResIII PF04851.10 KEP63816.1 - 0.024 14.4 0.0 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 KEP63816.1 - 0.026 14.1 0.1 0.77 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 KEP63816.1 - 0.049 13.6 0.1 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 KEP63816.1 - 0.099 12.2 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 KEP63816.1 - 0.12 11.2 0.0 0.57 9.0 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_21 PF13304.1 KEP63816.1 - 0.19 11.6 0.1 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KEP63816.1 - 0.31 9.6 0.0 0.51 8.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RINT1_TIP1 PF04437.8 KEP63818.1 - 0.00017 20.2 0.0 0.0003 19.4 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family LNS2 PF08235.8 KEP63819.1 - 1.4e-64 216.4 0.0 2.2e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KEP63819.1 - 4.8e-29 100.2 0.0 1.2e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region GATA PF00320.22 KEP63819.1 - 0.042 13.1 0.4 0.15 11.4 0.3 1.9 1 0 0 1 1 1 0 GATA zinc finger TTL PF03133.10 KEP63820.1 - 2.7e-76 256.3 0.2 4.1e-76 255.7 0.2 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEP63820.1 - 1.6e-06 27.0 0.0 0.00028 19.7 0.0 2.7 2 0 0 2 2 2 2 YheC/D like ATP-grasp RimK PF08443.6 KEP63820.1 - 0.026 14.0 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 KEP63820.1 - 0.026 13.6 0.0 6.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.9 KEP63820.1 - 0.029 14.2 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEP63820.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF2362 PF10154.4 KEP63822.1 - 1.5e-16 60.1 0.1 2.4e-09 36.4 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2362) Oxidored-like PF09791.4 KEP63823.1 - 2.6e-12 45.9 5.1 4.4e-12 45.2 3.5 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal FAST_1 PF06743.10 KEP63824.1 - 0.00096 18.8 0.0 0.012 15.2 0.0 2.7 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 DUF1510 PF07423.6 KEP63824.1 - 0.31 10.3 0.3 0.53 9.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF778 PF05608.7 KEP63825.1 - 2.8e-38 130.9 0.7 1.5e-37 128.5 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF778) DUF4632 PF15451.1 KEP63826.1 - 0.35 10.8 2.4 2.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) FRG2 PF15315.1 KEP63828.1 - 0.04 13.9 1.1 0.06 13.3 0.8 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 YchF-GTPase_C PF06071.8 KEP63833.1 - 1.2e-40 137.2 1.4 2.3e-40 136.2 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KEP63833.1 - 2.1e-17 63.1 0.0 8.3e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP63833.1 - 1.7e-06 27.4 0.0 4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 KEP63833.1 - 0.005 17.6 0.0 0.061 14.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain MobB PF03205.9 KEP63833.1 - 0.0085 15.8 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KEP63833.1 - 0.026 14.7 0.0 0.35 11.0 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) TGS PF02824.16 KEP63833.1 - 0.031 14.0 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 TGS domain SecA_PP_bind PF01043.15 KEP63833.1 - 0.091 13.1 0.2 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 SecA preprotein cross-linking domain ArgK PF03308.11 KEP63833.1 - 0.11 11.2 0.1 0.31 9.7 0.0 1.8 2 0 0 2 2 2 0 ArgK protein Cas6 PF09559.5 KEP63833.1 - 0.11 12.1 0.2 2.6 7.7 0.0 2.3 1 1 1 2 2 2 0 Cas6 Crispr RCR PF12273.3 KEP63834.1 - 1.2 9.7 10.0 2.1 8.9 0.9 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TORC_M PF12885.2 KEP63834.1 - 1.2 8.8 5.4 1 9.1 0.2 2.7 3 0 0 3 3 3 0 Transducer of regulated CREB activity middle domain U79_P34 PF03064.11 KEP63834.1 - 4.5 6.7 20.1 6.8 6.1 6.2 2.5 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DnaJ PF00226.26 KEP63835.1 - 2.5e-07 30.3 0.2 6.1e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain Sugar_tr PF00083.19 KEP63836.1 - 7.8e-88 295.0 27.4 9.6e-88 294.7 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEP63836.1 - 4.8e-35 120.9 45.4 1.3e-30 106.3 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEP63836.1 - 3.6e-08 32.0 1.0 3.6e-08 32.0 0.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Laminin_G_3 PF13385.1 KEP63838.1 - 2e-14 54.1 0.1 1.3e-06 28.7 0.0 3.8 3 1 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily GCC2_GCC3 PF07699.8 KEP63838.1 - 4.8e-07 29.2 16.1 2.9e-06 26.7 3.3 3.8 3 1 0 3 3 3 1 GCC2 and GCC3 DJ-1_PfpI PF01965.19 KEP63839.1 - 1.8e-29 102.0 0.2 2.4e-29 101.6 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KEP63839.1 - 5.6e-12 45.2 0.1 7.1e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 KEP63839.1 - 0.066 12.8 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PAPS_reduct PF01507.14 KEP63840.1 - 3.1e-18 66.1 0.1 2.5e-12 46.9 0.0 3.4 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family GTP_EFTU PF00009.22 KEP63841.1 - 1.8e-32 112.2 0.0 1.8e-32 112.2 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEP63841.1 - 3.7e-20 71.8 0.1 1e-19 70.4 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KEP63841.1 - 1.4e-13 50.7 6.4 1.7e-08 34.4 0.1 3.4 4 0 0 4 4 4 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KEP63841.1 - 7.9e-08 31.8 0.1 2.3e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KEP63841.1 - 5.3e-06 26.3 0.0 2e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF211 PF02680.9 KEP63841.1 - 0.059 13.1 1.6 0.11 12.3 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 PPDK_N PF01326.14 KEP63842.1 - 1.7e-25 89.7 0.0 1.4e-23 83.4 0.0 3.8 2 1 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Bromodomain PF00439.20 KEP63844.1 - 2.6e-14 52.8 0.0 4.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Strep_67kDa_ant PF06100.6 KEP63844.1 - 1.6 7.0 0.0 2.5 6.3 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Nop14 PF04147.7 KEP63844.1 - 4.4 5.0 5.6 11 3.8 3.9 1.6 1 0 0 1 1 1 0 Nop14-like family Dopey_N PF04118.9 KEP63845.1 - 2.8e-84 282.5 0.0 5.8e-84 281.4 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal F-protein PF00469.15 KEP63845.1 - 1.2 8.4 4.2 4.8 6.5 2.9 2.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF4246 PF14033.1 KEP63845.1 - 4.5 5.7 2.8 9.3 4.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DKCLD PF08068.7 KEP63847.1 - 5.4e-28 96.7 0.0 1.8e-27 94.9 0.0 2.0 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.13 KEP63847.1 - 1.1e-23 83.9 0.1 1.7e-20 73.7 0.1 3.6 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KEP63847.1 - 3.3e-20 71.5 0.9 5.8e-20 70.7 0.6 1.4 1 0 0 1 1 1 1 PUA domain WD40 PF00400.27 KEP63848.1 - 3.2e-30 102.8 12.8 2.7e-07 30.1 0.0 10.5 11 1 0 11 11 11 5 WD domain, G-beta repeat Utp13 PF08625.6 KEP63848.1 - 3.8e-15 55.7 0.0 7.7e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KEP63848.1 - 0.0095 14.1 0.3 0.035 12.2 0.2 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Zip PF02535.17 KEP63848.1 - 0.8 8.6 3.2 1.2 8.0 1.6 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter SAG PF04092.8 KEP63849.1 - 1.2e-11 45.0 5.7 1.2e-07 32.1 1.6 2.4 2 0 0 2 2 2 2 SRS domain ENTH PF01417.15 KEP63850.1 - 4.2e-35 120.3 0.0 6.7e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 KEP63850.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 VHS domain Strabismus PF06638.6 KEP63850.1 - 0.35 9.1 0.8 16 3.6 0.4 2.1 2 0 0 2 2 2 0 Strabismus protein SR-25 PF10500.4 KEP63850.1 - 0.65 9.4 27.0 1.3 8.4 11.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2146 PF10220.4 KEP63850.1 - 5.5 4.8 5.6 7.7 4.3 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) PPTA PF01239.17 KEP63851.1 - 4.5e-12 44.7 3.8 0.0019 17.4 0.0 5.1 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat LRR_4 PF12799.2 KEP63851.1 - 3.1e-05 23.4 0.2 0.0057 16.2 0.1 2.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP63851.1 - 0.008 15.9 0.3 0.018 14.7 0.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KEP63851.1 - 0.0083 16.0 0.8 0.32 11.1 0.0 3.1 2 1 1 3 3 3 1 Leucine Rich Repeat Tim17 PF02466.14 KEP63852.1 - 6.3e-15 55.3 4.2 7.9e-15 55.0 2.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Atg14 PF10186.4 KEP63856.1 - 0.009 14.9 0.1 0.02 13.8 0.0 1.5 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Myosin_HC-like PF07058.6 KEP63856.1 - 2.3 7.2 3.3 5.1 6.0 2.3 1.5 1 0 0 1 1 1 0 Myosin II heavy chain-like Yip1 PF04893.12 KEP63857.1 - 1.8e-09 37.3 11.2 2.9e-09 36.6 7.8 1.4 1 0 0 1 1 1 1 Yip1 domain FbpA PF05833.6 KEP63859.1 - 8.3e-26 90.5 10.1 1.4e-20 73.3 0.0 3.6 4 0 0 4 4 4 2 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 KEP63859.1 - 1.5e-23 82.5 0.1 7.8e-23 80.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KEP63859.1 - 4e-21 74.6 1.6 7.2e-21 73.8 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF814) DUF1098 PF06497.6 KEP63860.1 - 0.19 11.8 3.7 0.43 10.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1098) Arm PF00514.18 KEP63862.1 - 2.2e-12 46.3 40.2 3e-07 30.0 0.7 8.8 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat Sensor PF13796.1 KEP63862.1 - 0.028 14.0 1.6 0.21 11.1 0.1 2.8 2 0 0 2 2 2 0 Putative sensor HEAT_2 PF13646.1 KEP63862.1 - 0.066 13.4 11.9 0.51 10.6 0.0 5.2 4 2 0 4 4 4 0 HEAT repeats DNA_photolyase PF00875.13 KEP63862.1 - 0.079 12.7 0.6 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 DNA photolyase Fumarate_red_C PF02300.12 KEP63864.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit C TSP_1 PF00090.14 KEP63864.1 - 0.3 11.2 8.6 0.72 10.0 0.6 3.2 2 0 0 2 2 2 0 Thrombospondin type 1 domain Sporozoite_P67 PF05642.6 KEP63864.1 - 0.8 7.4 3.7 1.3 6.8 2.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PADR1 PF08063.7 KEP63864.1 - 1 8.8 6.9 0.2 11.1 0.1 2.8 3 0 0 3 3 3 0 PADR1 (NUC008) domain LCM PF04072.9 KEP63865.1 - 5.6e-25 87.9 0.1 1.3e-22 80.2 0.0 2.4 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase NifU_N PF01592.11 KEP63866.1 - 3.1e-46 156.4 0.1 4.1e-46 156.0 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain KH_1 PF00013.24 KEP63868.1 - 2.1e-07 30.4 0.2 4.2e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KEP63868.1 - 3.6e-06 26.4 0.2 3.6e-05 23.2 0.1 2.4 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 KEP63868.1 - 0.0077 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 KH domain FAST_1 PF06743.10 KEP63870.1 - 0.037 13.7 0.0 0.15 11.7 0.0 2.0 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 PP2C PF00481.16 KEP63873.1 - 9.5e-44 149.6 0.0 1.4e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEP63873.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEP63873.1 - 0.034 13.8 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) EF-hand_7 PF13499.1 KEP63874.1 - 4e-13 49.2 0.7 4.2e-07 30.0 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP63874.1 - 6.6e-12 44.2 4.3 1.5e-07 30.6 0.1 5.1 5 1 1 6 6 6 1 EF-hand domain EF-hand_8 PF13833.1 KEP63874.1 - 1.1e-09 37.7 2.9 0.0063 16.1 0.0 4.6 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KEP63874.1 - 2.4e-09 35.7 8.6 2.3e-06 26.5 0.1 4.9 6 0 0 6 6 6 2 EF hand EF-hand_9 PF14658.1 KEP63874.1 - 0.0011 18.8 0.0 0.0039 17.0 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KEP63874.1 - 0.0053 16.0 0.2 0.0053 16.0 0.1 3.6 4 0 0 4 4 4 1 EF hand DUF3847 PF12958.2 KEP63874.1 - 0.053 13.2 0.1 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) EFhand_Ca_insen PF08726.5 KEP63874.1 - 0.1 12.5 0.2 21 5.1 0.0 3.6 2 2 0 2 2 2 0 Ca2+ insensitive EF hand IMS PF00817.15 KEP63875.1 - 6.6e-30 103.8 0.0 1.2e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family BRCT PF00533.21 KEP63875.1 - 6.8e-07 29.3 0.1 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_C PF11799.3 KEP63875.1 - 0.00027 20.8 0.0 0.00093 19.1 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KEP63875.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif GCV_T PF01571.16 KEP63876.1 - 7.3e-55 185.6 0.1 1.1e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KEP63876.1 - 3.7e-11 42.9 0.0 8.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DER1 PF04511.10 KEP63877.1 - 1.6e-15 57.1 0.0 3.1e-08 33.3 0.0 3.1 3 0 0 3 3 3 3 Der1-like family IL11 PF07400.6 KEP63878.1 - 0.012 15.1 1.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 0 Interleukin 11 CAP PF00188.21 KEP63879.1 - 3.2e-08 34.1 0.3 7.8e-08 32.8 0.2 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Hyccin PF09790.4 KEP63879.1 - 0.082 11.7 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Hyccin DDHD PF02862.12 KEP63879.1 - 0.74 9.5 7.9 3.8 7.2 2.9 2.2 2 0 0 2 2 2 0 DDHD domain DUF2200 PF09966.4 KEP63880.1 - 0.54 10.1 0.0 1.1 9.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) AP2 PF00847.15 KEP63880.1 - 3.6 7.7 5.6 5.5 7.2 0.3 2.4 2 0 0 2 2 2 0 AP2 domain PP2C PF00481.16 KEP63884.1 - 4.8e-21 75.2 7.3 2.5e-16 59.8 0.0 4.5 5 0 0 5 5 5 3 Protein phosphatase 2C LRR_6 PF13516.1 KEP63885.1 - 0.0013 18.5 0.1 2.6 8.3 0.0 3.8 2 1 1 3 3 3 1 Leucine Rich repeat Peptidase_S49_N PF08496.5 KEP63885.1 - 0.094 12.5 0.5 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TLD PF07534.11 KEP63886.1 - 1e-22 80.6 0.0 2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 KEP63886.1 - 4e-13 49.3 0.0 5.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1014 PF06244.7 KEP63888.1 - 1e-34 119.3 3.4 1e-34 119.3 2.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 KEP63888.1 - 0.00094 19.3 0.3 0.00094 19.3 0.2 3.3 2 1 0 3 3 3 1 HMG (high mobility group) box CHDNT PF08073.7 KEP63888.1 - 0.027 14.1 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.8 KEP63888.1 - 2.1 8.5 11.0 0.093 12.9 1.1 2.1 1 1 1 2 2 2 0 YABBY protein Vfa1 PF08432.5 KEP63888.1 - 7.6 6.5 15.3 12 5.8 10.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 EMP24_GP25L PF01105.19 KEP63889.1 - 6.6e-16 58.5 0.0 7.9e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD WGG PF10273.4 KEP63890.1 - 1.1e-14 54.2 0.1 1.8e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 MCM PF00493.18 KEP63892.1 - 7.3e-118 393.1 0.0 9.9e-118 392.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEP63892.1 - 1.2e-08 35.4 0.2 4e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEP63892.1 - 4.9e-08 32.3 0.1 0.00011 21.4 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEP63892.1 - 1.1e-06 28.4 0.0 2.9e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEP63892.1 - 3.2e-05 23.5 0.0 7.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase_Tyr PF07714.12 KEP63893.1 - 6.1e-43 146.7 0.0 1.2e-42 145.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEP63893.1 - 1.9e-42 145.1 0.0 5.3e-30 104.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain FA_desaturase PF00487.19 KEP63894.1 - 3.8e-29 101.9 14.2 5.6e-29 101.3 9.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KEP63894.1 - 1.5e-17 62.4 0.4 2.6e-17 61.7 0.3 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) TauD PF02668.11 KEP63897.1 - 0.033 13.8 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family AF0941-like PF14591.1 KEP63897.1 - 0.42 10.6 5.0 0.27 11.2 1.3 2.0 1 1 0 2 2 2 0 AF0941-like MCR_beta PF02241.13 KEP63899.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain Peptidase_A22B PF04258.8 KEP63900.1 - 3.2e-68 230.3 8.5 4.4e-68 229.9 5.9 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PRA1 PF03208.14 KEP63900.1 - 0.035 13.4 0.0 0.035 13.4 0.0 3.6 4 1 0 4 4 4 0 PRA1 family protein DUF1119 PF06550.6 KEP63900.1 - 0.2 10.7 14.4 0.03 13.4 3.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1119) SOR_SNZ PF01680.12 KEP63901.1 - 1.1e-107 358.2 6.7 1.1e-107 358.2 4.7 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 KEP63901.1 - 2.6e-07 29.9 5.8 2.2e-06 26.9 0.1 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG NanE PF04131.9 KEP63901.1 - 0.00013 21.0 1.3 0.029 13.3 0.0 2.8 1 1 2 3 3 3 2 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 KEP63901.1 - 0.0054 16.0 0.1 0.14 11.3 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 KEP63901.1 - 0.0054 15.9 3.5 0.12 11.5 0.1 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase Dus PF01207.12 KEP63901.1 - 0.0063 15.3 0.7 1.4 7.6 0.0 2.5 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 KEP63901.1 - 0.012 14.4 0.1 0.054 12.3 0.0 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase IGPS PF00218.16 KEP63901.1 - 0.025 13.6 0.0 0.2 10.6 0.0 2.1 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase OMPdecase PF00215.19 KEP63901.1 - 0.053 12.9 0.0 3.5 6.9 0.0 2.5 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DNA_pol3_delta2 PF13177.1 KEP63902.1 - 5.7e-16 58.6 0.0 1.2e-15 57.5 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KEP63902.1 - 1.8e-15 57.2 0.0 3.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP63902.1 - 1.7e-07 31.4 0.0 6e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP63902.1 - 3.2e-07 30.4 0.1 4.6e-06 26.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.6 KEP63902.1 - 1.7e-06 27.9 0.0 5.2e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_30 PF13604.1 KEP63902.1 - 4.9e-06 26.2 0.0 1.7e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KEP63902.1 - 5.2e-06 25.6 0.0 7.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.10 KEP63902.1 - 8.7e-06 24.6 0.0 0.0023 16.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KEP63902.1 - 5.6e-05 22.8 0.0 0.00018 21.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KEP63902.1 - 0.00012 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEP63902.1 - 0.00018 20.6 0.0 0.00048 19.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEP63902.1 - 0.00019 20.9 0.1 0.00051 19.5 0.0 1.9 2 1 0 2 2 1 1 AAA domain KTI12 PF08433.5 KEP63902.1 - 0.00036 19.8 0.0 0.00062 19.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 KEP63902.1 - 0.00037 20.2 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 KEP63902.1 - 0.00039 19.9 0.0 0.067 12.6 0.0 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 KEP63902.1 - 0.00046 19.8 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEP63902.1 - 0.0008 18.9 0.4 0.81 9.0 0.0 3.0 2 1 1 3 3 3 1 AAA-like domain TIP49 PF06068.8 KEP63902.1 - 0.0018 17.0 0.0 0.13 10.9 0.0 2.4 2 1 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 KEP63902.1 - 0.002 18.4 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEP63902.1 - 0.0021 18.0 0.0 0.0051 16.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain ArgK PF03308.11 KEP63902.1 - 0.0029 16.4 0.1 1.2 7.8 0.0 2.3 1 1 1 2 2 2 2 ArgK protein Arch_ATPase PF01637.13 KEP63902.1 - 0.0031 17.2 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KEP63902.1 - 0.0031 17.0 0.2 0.12 11.8 0.0 2.4 1 1 1 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 KEP63902.1 - 0.0037 16.6 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 KEP63902.1 - 0.0038 18.0 0.0 0.0088 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEP63902.1 - 0.0054 15.9 0.1 0.026 13.6 0.1 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI SNF2_N PF00176.18 KEP63902.1 - 0.0065 15.3 0.1 0.08 11.7 0.0 2.1 1 1 0 2 2 2 1 SNF2 family N-terminal domain RNA_helicase PF00910.17 KEP63902.1 - 0.0083 16.2 0.0 0.034 14.3 0.0 2.1 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 KEP63902.1 - 0.011 15.3 0.1 0.023 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 KEP63902.1 - 0.012 15.0 0.1 0.06 12.8 0.1 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_2 PF07724.9 KEP63902.1 - 0.039 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KEP63902.1 - 0.042 13.0 0.3 2.8 7.1 0.0 2.3 1 1 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 KEP63902.1 - 0.087 12.6 0.1 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KEP63902.1 - 0.093 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.9 KEP63902.1 - 0.093 11.6 0.0 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase RAP PF08373.5 KEP63903.1 - 6.2e-15 54.7 0.0 1.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 RAP domain AP2 PF00847.15 KEP63904.1 - 0.0036 17.4 1.1 0.0036 17.4 0.8 3.0 3 0 0 3 3 3 1 AP2 domain CAF1-p150_N PF15557.1 KEP63905.1 - 4.4 6.5 6.3 6.7 5.9 0.2 2.6 3 0 0 3 3 3 0 CAF1 complex subunit p150, region binding to PCNA DUF1298 PF06974.8 KEP63908.1 - 0.0019 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.11 KEP63908.1 - 0.1 12.1 4.6 1.3 8.5 0.0 4.0 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RNase_T PF00929.19 KEP63909.1 - 9.9e-17 61.6 0.0 1.7e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Thr_synth_N PF14821.1 KEP63910.1 - 0.026 14.5 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 Threonine synthase N terminus RAP PF08373.5 KEP63911.1 - 2e-05 24.2 0.1 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 KEP63911.1 - 0.002 17.7 0.2 7.5 6.3 0.1 4.5 2 2 3 5 5 5 2 FAST kinase-like protein, subdomain 1 CRAL_TRIO PF00650.15 KEP63912.1 - 6.6e-30 103.6 0.1 9.2e-30 103.2 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KEP63912.1 - 2e-08 34.2 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEP63912.1 - 0.031 14.4 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain ketoacyl-synt PF00109.21 KEP63913.1 - 3.2e-27 95.6 0.2 8.4e-27 94.2 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEP63913.1 - 3.9e-25 88.5 0.1 8.1e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEP63913.1 - 2.2e-13 50.4 0.0 5.1e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEP63913.1 - 1.5e-11 44.1 0.0 3.9e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEP63913.1 - 2.4e-10 40.5 0.2 6.3e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 KEP63913.1 - 8.1e-08 31.9 0.1 4.5e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.21 KEP63914.1 - 2.4e-63 214.0 0.5 3.8e-63 213.3 0.4 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 KEP63914.1 - 5.5e-55 186.4 0.0 1.7e-54 184.8 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Ketoacyl-synt_C PF02801.17 KEP63914.1 - 1.2e-32 112.2 0.0 2.7e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEP63914.1 - 4.3e-09 36.5 0.0 8.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C_2 PF14535.1 KEP63914.1 - 0.088 12.8 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain C1_2 PF03107.11 KEP63915.1 - 0.046 13.8 0.7 0.046 13.8 0.5 12.5 12 1 1 13 13 13 0 C1 domain Senescence_reg PF04520.8 KEP63915.1 - 0.26 11.7 4.7 22 5.5 0.1 3.7 3 1 0 3 3 3 0 Senescence regulator SNF2_N PF00176.18 KEP63917.1 - 5.6e-56 189.5 0.0 5.6e-56 189.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain PHD PF00628.24 KEP63917.1 - 8.3e-21 73.4 77.6 5.6e-09 35.5 4.9 7.0 6 1 0 6 6 6 4 PHD-finger Helicase_C PF00271.26 KEP63917.1 - 1.1e-13 50.7 0.0 4.3e-13 48.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP63917.1 - 5.2e-05 22.8 0.0 0.00025 20.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase C1_1 PF00130.17 KEP63917.1 - 0.0055 16.4 2.5 0.0055 16.4 1.8 7.3 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_14 PF13173.1 KEP63917.1 - 0.0065 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf-PHD-like PF15446.1 KEP63917.1 - 0.024 13.9 0.0 0.024 13.9 0.0 7.3 5 2 2 7 7 7 0 PHD/FYVE-zinc-finger like domain Rubredoxin PF00301.15 KEP63917.1 - 1.7 8.5 26.8 1.9 8.3 3.8 4.3 3 0 0 3 3 3 0 Rubredoxin MFS_1 PF07690.11 KEP63918.1 - 2.5e-30 105.3 27.6 2.5e-30 105.3 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEP63918.1 - 6.3e-09 34.9 23.4 4.7e-06 25.4 8.0 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 KEP63918.1 - 5.2e-07 28.5 7.1 5.2e-07 28.5 4.9 2.0 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KEP63918.1 - 2.5e-06 26.1 9.4 0.0017 16.8 0.4 2.3 1 1 0 2 2 2 2 MFS/sugar transport protein Gly-zipper_Omp PF13488.1 KEP63918.1 - 0.012 15.2 1.1 2 8.1 0.0 2.7 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 KEP63918.1 - 0.79 9.4 4.8 26 4.5 1.8 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain DSS1_SEM1 PF05160.8 KEP63922.1 - 2.7e-08 33.4 20.3 1.5e-06 27.8 14.1 2.4 1 1 0 1 1 1 1 DSS1/SEM1 family MatP PF06303.7 KEP63922.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome DUF4404 PF14357.1 KEP63922.1 - 0.16 12.4 3.6 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Cwf_Cwc_15 PF04889.7 KEP63922.1 - 0.75 9.4 5.1 0.86 9.2 3.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CCCH PF00642.19 KEP63923.1 - 6.3e-10 38.4 13.2 2.6e-05 23.7 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KEP63923.1 - 5.9e-09 35.6 0.1 9.7e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP63923.1 - 1.5e-06 27.6 0.1 3.6e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP63923.1 - 0.0069 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4173 PF13777.1 KEP63924.1 - 0.22 10.7 8.9 7.8 5.7 6.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4173) DUF1802 PF08819.6 KEP63925.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) ALMT PF11744.3 KEP63925.1 - 0.054 12.1 0.0 0.062 11.9 0.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hydrolase PF00702.21 KEP63927.1 - 1.5e-19 71.2 0.0 7.1e-10 39.6 0.0 4.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP63927.1 - 7.4e-18 65.4 0.0 1e-16 61.7 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEP63927.1 - 3.6e-14 52.3 0.0 3.4e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KEP63927.1 - 0.0035 17.2 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF4128 PF13554.1 KEP63927.1 - 0.17 11.5 0.1 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function zf-C2HC_2 PF13913.1 KEP63928.1 - 2.5e-13 49.2 12.2 3.6e-08 32.8 0.6 2.7 2 0 0 2 2 2 2 zinc-finger of a C2HC-type RepA_C PF04796.7 KEP63930.1 - 0.013 15.1 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Plasmid encoded RepA protein RNA_pol PF00940.14 KEP63932.1 - 0.24 9.8 0.0 0.35 9.2 0.0 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase Spore_coat_CotO PF14153.1 KEP63932.1 - 5.6 6.3 10.1 3.5 7.0 0.9 2.3 2 0 0 2 2 2 0 Spore coat protein CotO TBPIP PF07106.8 KEP63934.1 - 0.54 9.7 5.0 0.19 11.2 0.7 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MAT1 PF06391.8 KEP63934.1 - 0.84 9.1 5.7 0.92 9.0 2.6 1.9 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 ApoLp-III PF07464.6 KEP63934.1 - 1.1 9.2 5.7 0.89 9.5 0.2 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) zf-C3HC4_2 PF13923.1 KEP63935.1 - 3.4e-07 30.1 4.9 3.4e-07 30.1 3.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP63935.1 - 7.1e-07 28.9 5.3 7.1e-07 28.9 3.7 2.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 KEP63935.1 - 1.1e-05 24.9 1.7 1.1e-05 24.9 1.2 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP63935.1 - 0.00025 20.7 5.1 0.00025 20.7 3.6 3.2 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEP63935.1 - 0.0018 17.9 1.0 0.0018 17.9 0.7 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEP63935.1 - 0.0049 16.7 4.8 0.0049 16.7 3.3 2.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KEP63935.1 - 5.1 7.2 6.4 0.67 10.1 0.7 2.3 3 0 0 3 3 3 0 RING-H2 zinc finger BpuJI_N PF11564.3 KEP63936.1 - 0.43 9.4 0.0 0.66 8.8 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal START PF01852.14 KEP63937.1 - 5.7e-13 48.6 0.1 1.5e-12 47.2 0.1 1.6 1 1 0 1 1 1 1 START domain DUF3694 PF12473.3 KEP63937.1 - 0.23 11.0 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 Kinesin protein DEAD PF00270.24 KEP63938.1 - 3.8e-42 143.6 0.0 7.1e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP63938.1 - 4.5e-28 96.9 0.0 9.2e-28 95.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP63938.1 - 0.00062 19.6 0.0 0.0026 17.6 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KEP63938.1 - 0.0023 17.6 0.0 0.42 10.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Helicase_C_2 PF13307.1 KEP63938.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain zf-RING_2 PF13639.1 KEP63939.1 - 9.4e-14 50.9 8.8 1.9e-13 49.9 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP63939.1 - 1.6e-10 40.8 2.5 4.5e-10 39.4 1.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEP63939.1 - 1.6e-06 27.9 9.7 3.4e-06 26.9 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP63939.1 - 2.3e-06 27.1 9.3 4.8e-06 26.1 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP63939.1 - 1e-05 25.1 5.8 1e-05 25.1 4.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP63939.1 - 0.00012 21.7 8.5 0.00029 20.5 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain RINGv PF12906.2 KEP63939.1 - 0.013 15.4 10.4 0.03 14.3 7.2 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 KEP63939.1 - 0.033 14.0 6.1 0.083 12.7 4.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KEP63939.1 - 0.14 11.7 4.1 0.3 10.6 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 KEP63939.1 - 0.92 9.5 8.1 2.2 8.2 5.6 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Pkinase PF00069.20 KEP63941.1 - 3.3e-10 39.5 0.0 5.9e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63941.1 - 9.1e-07 28.2 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP63941.1 - 1.2e-05 24.4 0.0 1.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YfzA PF14118.1 KEP63941.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 YfzA-like protein Ank_2 PF12796.2 KEP63942.1 - 1.9e-28 98.5 0.2 7e-13 48.7 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEP63942.1 - 4.2e-23 79.9 0.8 5.6e-07 29.0 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KEP63942.1 - 4.1e-22 78.1 0.3 1.3e-08 35.0 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEP63942.1 - 2.2e-21 75.3 1.0 8.2e-08 32.2 0.0 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP63942.1 - 1.2e-18 65.2 0.3 0.00079 19.4 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat DUF1843 PF08898.5 KEP63942.1 - 5.1e-06 26.4 0.8 0.00046 20.1 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) Ribosomal_L7Ae PF01248.21 KEP63943.1 - 2.8e-26 90.8 0.2 3.9e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KEP63943.1 - 0.021 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 Lysine_decarbox PF03641.9 KEP63944.1 - 6.9e-25 87.4 0.0 1.2e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase Retrotrans_gag PF03732.12 KEP63944.1 - 0.025 14.6 0.5 0.05 13.6 0.4 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RRM_6 PF14259.1 KEP63947.1 - 8.4e-35 118.5 0.0 1.4e-10 41.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP63947.1 - 2.8e-24 84.5 0.0 1.3e-07 31.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP63947.1 - 2.6e-11 43.1 0.0 0.032 14.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cullin_binding PF03556.10 KEP63948.1 - 7.3e-30 103.5 1.0 1.2e-29 102.7 0.7 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 KEP63948.1 - 1.1e-09 37.6 0.0 2.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DUF2453 PF10507.4 KEP63950.1 - 7e-38 128.8 0.1 1.2e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) GAF_3 PF13492.1 KEP63950.1 - 4.1e-09 36.5 0.1 2.4e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.1 KEP63950.1 - 1.5e-08 35.2 0.2 3.1e-07 30.9 0.0 2.7 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 KEP63950.1 - 1.1e-06 28.8 0.1 7.1e-06 26.2 0.1 2.4 1 1 0 1 1 1 1 GAF domain DUF1510 PF07423.6 KEP63953.1 - 9.8e-05 21.8 9.2 0.00013 21.4 6.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) NOA36 PF06524.7 KEP63953.1 - 0.012 14.9 8.3 0.014 14.7 5.7 1.1 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 KEP63953.1 - 0.021 13.9 10.4 0.021 13.9 7.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Trypan_PARP PF05887.6 KEP63953.1 - 0.033 14.0 13.5 0.042 13.6 9.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 KEP63953.1 - 0.12 10.2 15.2 0.12 10.2 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family U79_P34 PF03064.11 KEP63953.1 - 0.29 10.6 10.1 0.34 10.4 7.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Zip PF02535.17 KEP63953.1 - 0.38 9.7 2.0 0.42 9.5 1.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 KEP63953.1 - 0.56 10.0 10.6 0.65 9.8 7.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 KEP63953.1 - 0.6 9.2 7.5 0.67 9.0 5.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 KEP63953.1 - 1 9.1 4.4 1.1 8.9 3.0 1.1 1 0 0 1 1 1 0 DDHD domain NPR3 PF03666.8 KEP63953.1 - 1.4 7.3 3.7 1.6 7.1 2.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ycf1 PF05758.7 KEP63953.1 - 2.2 5.8 5.2 2.8 5.5 3.6 1.2 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 KEP63953.1 - 2.2 6.1 12.8 2.5 6.0 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KEP63953.1 - 2.3 6.5 19.4 2.7 6.3 13.4 1.1 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 KEP63953.1 - 2.7 6.7 7.5 3 6.6 5.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PPP4R2 PF09184.6 KEP63953.1 - 3.8 6.9 17.9 4.6 6.7 12.4 1.1 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.9 KEP63953.1 - 6.3 6.2 12.3 8.5 5.8 8.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 KEP63953.1 - 6.5 6.3 18.2 3.2 7.2 11.1 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-RING_5 PF14634.1 KEP63954.1 - 0.0029 17.2 10.9 0.0061 16.2 7.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEP63954.1 - 0.012 15.2 11.5 0.026 14.2 7.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP63954.1 - 0.018 15.0 12.6 0.042 13.8 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP63954.1 - 0.02 14.6 11.6 0.045 13.5 8.0 1.6 1 0 0 1 1 1 0 Ring finger domain zinc-ribbons_6 PF07191.7 KEP63954.1 - 0.2 11.4 7.9 0.41 10.4 5.5 1.5 1 0 0 1 1 1 0 zinc-ribbons PP2C PF00481.16 KEP63955.1 - 1.7e-43 148.8 3.0 4.8e-42 144.1 0.9 3.2 2 1 0 2 2 2 1 Protein phosphatase 2C RCC1 PF00415.13 KEP63956.1 - 1.4e-23 82.8 18.3 2.5e-08 34.0 0.0 8.3 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP63956.1 - 1.4e-19 69.1 34.3 1.7e-10 40.1 0.8 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.6 KEP63956.1 - 0.076 12.2 0.1 0.73 9.0 0.0 2.5 3 0 0 3 3 3 0 TUP1-like enhancer of split HIRA_B PF09453.5 KEP63956.1 - 0.2 11.2 0.7 0.58 9.7 0.5 1.8 1 0 0 1 1 1 0 HIRA B motif Pkinase PF00069.20 KEP63957.1 - 1.9e-40 138.6 0.0 2.9e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63957.1 - 1.5e-20 73.3 0.0 1e-19 70.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP63957.1 - 0.0032 16.4 0.0 0.15 10.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like PCI PF01399.22 KEP63958.1 - 1.1e-10 41.7 0.0 3.9e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KEP63958.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 KEP63958.1 - 0.00035 20.4 3.1 0.072 13.0 0.5 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEP63958.1 - 0.0014 18.3 1.1 7.1 6.8 0.2 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP63958.1 - 0.003 17.2 4.9 0.076 12.8 0.2 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEP63958.1 - 0.011 16.1 2.5 33 5.2 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP63958.1 - 0.024 14.2 0.0 24 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEP63958.1 - 0.049 13.9 1.2 3.5 8.0 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEP63958.1 - 0.095 13.4 11.8 0.057 14.1 1.8 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat Myco_19_kDa PF05481.7 KEP63958.1 - 3.8 7.3 8.6 1.6 8.5 0.2 2.3 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen TPR_14 PF13428.1 KEP63958.1 - 4.8 8.1 18.6 1.9 9.3 0.5 6.0 7 1 2 9 9 7 0 Tetratricopeptide repeat DUF3446 PF11928.3 KEP63958.1 - 6.9 6.9 23.7 8.3 6.6 4.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Peptidase_M16 PF00675.15 KEP63959.1 - 1.5e-53 180.5 0.1 6.7e-53 178.4 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEP63959.1 - 3e-40 137.8 0.0 1.4e-39 135.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain DNA_mis_repair PF01119.14 KEP63960.1 - 7.9e-17 60.8 0.0 1.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 KEP63960.1 - 1.8e-12 47.0 1.0 2.1e-09 37.1 0.0 2.9 3 0 0 3 3 3 2 MutL C terminal dimerisation domain HATPase_c PF02518.21 KEP63960.1 - 1.3e-10 40.9 0.0 2.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEP63960.1 - 2.4e-10 40.2 0.0 6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Coa1 PF08695.5 KEP63962.1 - 0.00069 19.0 0.0 0.018 14.5 0.0 3.1 4 0 0 4 4 4 1 Cytochrome oxidase complex assembly protein 1 ATP-synt_ab PF00006.20 KEP63963.1 - 8e-06 25.4 0.1 0.041 13.3 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KEP63963.1 - 0.0022 17.4 0.6 0.006 16.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEP63963.1 - 0.13 12.0 6.1 0.069 12.9 0.2 3.2 3 0 0 3 3 3 0 Part of AAA domain SRP9-21 PF05486.7 KEP63964.1 - 1e-14 53.9 0.1 1.9e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Autophagy_N PF03986.8 KEP63966.1 - 4.8e-30 104.2 0.0 7.8e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KEP63966.1 - 3.9e-27 94.2 0.1 6.8e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KEP63966.1 - 1.1e-12 46.8 1.4 2.1e-12 45.9 1.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Rep_fac-A_C PF08646.5 KEP63969.1 - 5.1e-29 100.8 1.5 4.9e-28 97.6 0.5 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 KEP63969.1 - 1.3e-13 50.6 0.0 5.3e-10 39.0 0.0 2.8 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain DUF4539 PF15072.1 KEP63969.1 - 0.01 15.5 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) tRNA_anti_2 PF13742.1 KEP63969.1 - 0.026 14.3 0.0 0.096 12.5 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain P5CR_dimer PF14748.1 KEP63970.1 - 1.2e-37 128.2 0.2 2e-37 127.4 0.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KEP63970.1 - 3.1e-14 53.1 0.3 5.8e-14 52.2 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KEP63970.1 - 0.00035 20.3 0.9 0.087 12.5 0.2 2.6 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KEP63970.1 - 0.0015 18.3 0.1 0.0026 17.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 KEP63970.1 - 0.055 13.9 0.1 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 KEP63970.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glycolytic PF00274.14 KEP63972.1 - 7.2e-172 570.5 0.0 8.5e-172 570.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Trp_halogenase PF04820.9 KEP63972.1 - 0.099 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Glycolytic PF00274.14 KEP63973.1 - 6.8e-126 419.3 0.0 7.5e-126 419.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I HrpB1_HrpK PF09613.5 KEP63973.1 - 0.098 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF775 PF05603.7 KEP63974.1 - 4e-20 72.2 0.0 6e-19 68.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF775) BT1 PF03092.11 KEP63975.1 - 3.5e-51 174.2 22.6 8.5e-50 169.7 15.7 2.0 1 1 0 1 1 1 1 BT1 family Prenylcys_lyase PF07156.9 KEP63976.1 - 1.7e-23 83.1 0.0 5.7e-16 58.3 0.0 2.5 1 1 1 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 KEP63976.1 - 2.4e-07 30.6 0.7 4.6e-06 26.5 0.5 2.6 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEP63976.1 - 0.0038 16.3 0.0 0.023 13.7 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 KEP63976.1 - 0.018 13.9 0.2 0.042 12.7 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KEP63976.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KEP63976.1 - 0.14 12.5 0.1 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fer2 PF00111.22 KEP63977.1 - 2.3e-08 33.6 2.0 2.3e-08 33.6 1.4 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Daxx PF03344.10 KEP63978.1 - 7.2e-05 21.4 24.7 7.2e-05 21.4 17.1 2.6 3 0 0 3 3 3 1 Daxx Family MA3 PF02847.12 KEP63978.1 - 0.00022 20.8 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 KEP63978.1 - 0.0074 15.7 0.1 0.41 10.0 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain DUF3138 PF11336.3 KEP63978.1 - 0.64 8.1 0.1 0.99 7.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) IBR PF01485.16 KEP63979.1 - 8e-19 67.2 30.5 1.6e-10 40.6 8.0 4.0 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 KEP63979.1 - 0.0021 18.0 0.1 0.0021 18.0 0.1 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP63979.1 - 0.01 15.6 26.3 0.1 12.4 0.1 3.9 3 0 0 3 3 3 0 Ring finger domain Apt1 PF10351.4 KEP63979.1 - 0.025 13.4 1.9 0.046 12.5 1.3 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.5 KEP63979.1 - 1 8.9 15.9 0.14 11.8 8.1 1.7 2 0 0 2 2 2 0 Transcription factor PAP1 Med3 PF11593.3 KEP63979.1 - 6.2 5.9 8.1 10 5.2 5.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-RING_4 PF14570.1 KEP63979.1 - 8.3 6.0 31.5 0.41 10.2 8.4 3.9 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain GTP_EFTU PF00009.22 KEP63980.1 - 6.5e-38 130.0 0.0 1.1e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KEP63980.1 - 3.3e-34 116.7 0.0 6.6e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KEP63980.1 - 6.2e-11 42.2 1.8 1.6e-10 40.9 0.4 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEP63980.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Methyltransf_16 PF10294.4 KEP63981.1 - 2.7e-15 56.2 0.0 2.7e-05 23.6 0.0 3.3 3 0 0 3 3 3 3 Putative methyltransferase Methyltransf_26 PF13659.1 KEP63981.1 - 8.8e-05 22.5 0.1 0.00018 21.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Med21 PF11221.3 KEP63981.1 - 0.32 10.9 2.3 0.35 10.8 0.0 2.3 3 1 0 3 3 3 0 Subunit 21 of Mediator complex Peptidase_S8 PF00082.17 KEP63982.1 - 2.1e-52 178.0 7.2 3.6e-52 177.2 5.0 1.4 1 0 0 1 1 1 1 Subtilase family KH_1 PF00013.24 KEP63984.1 - 1.6e-23 82.1 0.0 8e-08 31.8 0.0 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 KEP63984.1 - 1.6e-11 43.5 0.1 0.011 15.3 0.0 4.4 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 KEP63984.1 - 8.9e-05 21.9 0.0 8.6 5.9 0.0 4.1 4 0 0 4 4 4 2 KH domain Dynein_heavy PF03028.10 KEP63985.1 - 6.5e-208 692.1 0.2 5.2e-206 685.9 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEP63985.1 - 8.8e-121 403.2 8.2 8.8e-121 403.2 5.7 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 KEP63985.1 - 6e-120 401.3 7.9 6e-120 401.3 5.5 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 KEP63985.1 - 1.7e-100 335.3 0.0 9.8e-100 332.8 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEP63985.1 - 1.4e-62 211.1 0.0 3e-62 210.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEP63985.1 - 3.3e-54 183.1 0.1 7.7e-54 181.9 0.1 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KEP63985.1 - 6e-52 176.4 12.4 1e-51 175.7 8.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KEP63985.1 - 2.2e-47 161.4 0.0 4e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KEP63985.1 - 8.8e-19 67.6 0.0 2.9e-06 27.0 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEP63985.1 - 3.2e-05 24.0 0.1 0.052 13.6 0.0 4.9 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 KEP63985.1 - 0.089 12.9 1.2 18 5.5 0.0 3.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEP63985.1 - 0.1 12.3 0.2 5.4 6.8 0.1 3.0 3 0 0 3 3 2 0 Part of AAA domain Cuticle_1 PF08140.6 KEP63985.1 - 0.55 10.1 0.0 1.5 8.6 0.0 1.8 1 0 0 1 1 1 0 Crustacean cuticle protein repeat zf-CCCH PF00642.19 KEP63986.1 - 4.6e-10 38.9 5.4 3.9e-06 26.3 0.6 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEP63986.1 - 0.11 12.5 5.9 1.2 9.2 0.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Lactamase_B_2 PF12706.2 KEP63987.1 - 1.6e-34 119.1 0.0 5.1e-34 117.5 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KEP63987.1 - 4.3e-07 29.3 0.1 1.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KEP63987.1 - 0.44 10.1 1.7 3.9 7.0 1.0 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily zf-RING-like PF08746.6 KEP63988.1 - 0.68 9.9 4.0 0.8 9.7 0.7 2.4 2 1 0 2 2 2 0 RING-like domain zf-AN1 PF01428.11 KEP63988.1 - 1.3 8.9 7.9 0.72 9.7 0.7 2.5 3 0 0 3 3 3 0 AN1-like Zinc finger TFIIS_C PF01096.13 KEP63988.1 - 1.8 8.2 5.2 2.4 7.8 0.1 2.7 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) MPC PF03650.8 KEP63989.1 - 8.6e-35 119.2 0.3 1.3e-34 118.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) FLO_LFY PF01698.11 KEP63989.1 - 0.049 12.4 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TPR_10 PF13374.1 KEP63990.1 - 0.027 14.4 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP63990.1 - 0.09 12.7 0.2 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S8 PF00082.17 KEP63991.1 - 6.4e-48 163.3 1.3 1e-47 162.6 0.9 1.3 1 0 0 1 1 1 1 Subtilase family EGF_3 PF12947.2 KEP63991.1 - 3.7e-15 55.5 36.0 0.0002 21.2 5.0 4.7 4 0 0 4 4 4 4 EGF domain EGF_CA PF07645.10 KEP63991.1 - 1.8e-12 47.0 18.3 4.3e-08 33.0 4.1 4.9 4 1 0 4 4 4 2 Calcium-binding EGF domain cEGF PF12662.2 KEP63991.1 - 3e-12 45.9 27.5 8.1e-06 25.3 2.7 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP63991.1 - 0.00024 21.1 43.4 0.0071 16.4 4.0 4.8 4 0 0 4 4 4 4 Coagulation Factor Xa inhibitory site Pkinase PF00069.20 KEP63992.1 - 2.3e-71 239.9 0.0 2.8e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP63992.1 - 1.8e-34 118.9 0.0 2.3e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP63992.1 - 2.1e-09 36.7 0.1 8.1e-08 31.5 0.0 2.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KEP63992.1 - 0.0017 18.1 0.0 0.0044 16.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEP63992.1 - 0.0053 15.8 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cytokin-bind PF09265.5 KEP63992.1 - 0.022 13.8 0.1 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding YrbL-PhoP_reg PF10707.4 KEP63992.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SMAP PF15477.1 KEP63993.1 - 1.3e-15 57.3 3.2 1.3e-15 57.3 2.2 4.2 4 1 0 4 4 4 1 Small acidic protein family FHA PF00498.21 KEP63993.1 - 1.4e-08 34.7 0.0 4.3e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 FHA domain DUF1777 PF08648.7 KEP63993.1 - 0.007 16.1 30.5 0.007 16.1 21.1 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1777) Creb_binding PF09030.5 KEP63993.1 - 0.016 15.4 2.2 0.016 15.4 1.5 2.1 2 0 0 2 2 2 0 Creb binding FoP_duplication PF13865.1 KEP63993.1 - 0.025 15.0 8.2 0.025 15.0 5.7 3.9 3 1 1 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 DUF4230 PF14014.1 KEP63993.1 - 0.07 12.9 2.2 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) Rpr2 PF04032.11 KEP63995.1 - 1.7e-13 50.2 10.9 1.7e-12 47.0 3.6 2.6 2 0 0 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain ELL PF10390.4 KEP63996.1 - 0.00071 18.8 0.1 0.00094 18.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL PBP1_TM PF14812.1 KEP63996.1 - 0.0012 19.1 1.3 0.002 18.3 0.9 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RNase_P_Rpp14 PF01900.14 KEP63996.1 - 0.0065 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF3899 PF13038.1 KEP63996.1 - 0.036 14.2 0.1 0.065 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Peptidase_S49_N PF08496.5 KEP63996.1 - 0.05 13.3 1.2 0.067 12.9 0.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FixQ PF05545.6 KEP63996.1 - 0.15 11.7 2.7 0.31 10.7 1.9 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Pex14_N PF04695.8 KEP63996.1 - 0.8 9.7 4.9 0.53 10.3 1.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.3 KEP63996.1 - 1.2 7.6 6.3 1.9 6.9 4.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDK2AP PF09806.4 KEP63996.1 - 8.3 6.5 12.6 79 3.4 8.7 2.0 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein FBPase PF00316.15 KEP63997.1 - 4.2e-67 226.2 0.0 5.1e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Peptidase_M16_C PF05193.16 KEP63999.1 - 1.7e-29 102.8 0.0 2.4e-16 59.9 0.0 3.4 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEP63999.1 - 5.1e-21 74.9 5.8 2.5e-20 72.7 0.8 3.4 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) TENA_THI-4 PF03070.11 KEP63999.1 - 0.092 12.4 2.7 0.074 12.7 0.3 2.0 2 0 0 2 2 2 0 TENA/THI-4/PQQC family DUF1682 PF07946.9 KEP64001.1 - 2.8e-64 217.0 0.2 3.4e-64 216.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) GLE1 PF07817.8 KEP64001.1 - 0.071 12.0 0.0 0.071 12.0 0.0 2.1 2 0 0 2 2 2 0 GLE1-like protein BSMAP PF12280.3 KEP64001.1 - 0.53 10.1 5.0 4.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Brain specific membrane anchored protein AlaDh_PNT_C PF01262.16 KEP64001.1 - 3.9 7.0 4.6 9.9 5.6 3.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Mito_carr PF00153.22 KEP64002.1 - 1.7e-32 110.9 3.0 4.1e-12 45.6 0.1 4.9 4 1 0 4 4 4 3 Mitochondrial carrier protein Formyl_trans_N PF00551.14 KEP64003.1 - 3.9e-26 91.6 0.0 9.1e-26 90.4 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 KEP64003.1 - 1.2e-09 38.1 0.0 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 2 Formyl transferase, C-terminal domain DUF2398 PF09661.5 KEP64004.1 - 0.024 13.3 0.1 0.064 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2398) DS PF01916.12 KEP64006.1 - 2.5e-128 427.4 0.0 3e-128 427.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase AAA PF00004.24 KEP64007.1 - 2e-73 244.7 0.0 1.6e-44 151.2 0.0 3.8 3 1 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP64007.1 - 2.5e-12 47.1 0.1 9.8e-07 28.9 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 KEP64007.1 - 5e-10 38.8 0.0 0.0013 17.7 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KEP64007.1 - 8.3e-09 35.5 0.0 0.049 13.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEP64007.1 - 2.2e-08 33.9 0.0 0.01 15.5 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEP64007.1 - 7.2e-08 32.6 0.1 0.00084 19.4 0.0 4.0 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.8 KEP64007.1 - 8.3e-08 31.3 0.0 0.00097 17.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 KEP64007.1 - 2.7e-07 31.4 0.0 0.00026 21.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 KEP64007.1 - 1.9e-06 27.1 1.3 0.0063 15.6 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin IstB_IS21 PF01695.12 KEP64007.1 - 3.4e-06 26.6 0.0 0.0045 16.4 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 KEP64007.1 - 7.3e-06 25.9 0.0 0.0037 17.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEP64007.1 - 1.5e-05 24.2 0.1 0.19 10.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEP64007.1 - 5.6e-05 23.2 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 KEP64007.1 - 8e-05 22.3 0.0 0.016 14.9 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KEP64007.1 - 0.00017 21.4 0.0 0.23 11.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 KEP64007.1 - 0.00022 20.6 0.3 1.1 8.6 0.0 4.4 4 1 1 5 5 5 1 AAA domain Sigma54_activ_2 PF14532.1 KEP64007.1 - 0.00029 20.8 0.0 0.31 11.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KEP64007.1 - 0.00047 19.8 0.0 0.12 12.0 0.0 3.1 4 0 0 4 4 2 1 NACHT domain AAA_28 PF13521.1 KEP64007.1 - 0.00061 19.7 0.1 0.1 12.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 KEP64007.1 - 0.0014 18.2 0.0 0.23 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KEP64007.1 - 0.0016 18.1 0.0 0.7 9.5 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 KEP64007.1 - 0.0036 17.6 0.0 0.015 15.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 KEP64007.1 - 0.0038 16.8 0.0 3.5 7.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KEP64007.1 - 0.0042 17.3 0.0 0.5 10.6 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 KEP64007.1 - 0.014 14.8 0.0 5.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 KEP64007.1 - 0.014 14.8 0.0 1.4 8.3 0.0 3.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KEP64007.1 - 0.03 13.9 0.0 0.62 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 KEP64007.1 - 0.044 12.6 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.8 KEP64007.1 - 0.045 12.6 0.0 8 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 KEP64007.1 - 0.052 13.1 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.12 KEP64007.1 - 0.073 11.9 0.0 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 KEP64007.1 - 0.079 12.6 0.0 7.1 6.2 0.0 2.9 2 1 1 3 3 3 0 NTPase AFG1_ATPase PF03969.11 KEP64007.1 - 0.08 11.7 0.0 5.2 5.7 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase KaiC PF06745.8 KEP64007.1 - 0.084 11.9 0.0 13 4.8 0.0 2.7 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 KEP64007.1 - 0.15 11.2 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Rad17 PF03215.10 KEP64007.1 - 0.16 10.5 0.0 0.54 8.8 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PHD PF00628.24 KEP64012.1 - 2.1e-15 56.1 71.1 9.7e-11 41.1 9.8 5.6 3 1 2 5 5 5 3 PHD-finger PHD_2 PF13831.1 KEP64012.1 - 9.4e-05 21.6 11.4 0.00042 19.5 0.8 5.3 5 1 0 5 5 5 3 PHD-finger C1_1 PF00130.17 KEP64012.1 - 0.00014 21.5 2.6 0.00014 21.5 1.8 6.6 4 3 3 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) eIF-5_eIF-2B PF01873.12 KEP64013.1 - 2.1e-37 127.5 0.1 2.9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 GCC2_GCC3 PF07699.8 KEP64013.1 - 0.17 11.4 4.9 2.3 7.8 0.6 2.3 1 1 1 2 2 2 0 GCC2 and GCC3 zf-RanBP PF00641.13 KEP64013.1 - 1.1 8.4 5.6 1.8 7.7 0.3 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others MORN PF02493.15 KEP64015.1 - 5.7e-29 98.0 50.8 5.3e-05 22.6 0.1 8.5 8 0 0 8 8 8 8 MORN repeat Hid1 PF12722.2 KEP64017.1 - 3e-120 402.4 0.0 1.4e-96 324.1 0.0 2.3 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KEP64017.1 - 1.6e-82 277.7 0.0 1.7e-80 271.0 0.0 2.3 2 1 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein MIP-T3 PF10243.4 KEP64018.1 - 2.7 6.3 40.3 4.1 5.7 27.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Fumble PF03630.9 KEP64019.1 - 3.6e-41 141.1 0.0 1.2e-21 76.9 0.0 3.5 4 0 0 4 4 4 3 Fumble Apt1 PF10351.4 KEP64019.1 - 9.7 4.9 4.2 29 3.3 2.9 1.9 1 1 0 1 1 1 0 Golgi-body localisation protein domain Myosin_head PF00063.16 KEP64020.1 - 7.9e-166 553.0 0.1 1.3e-165 552.2 0.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) ATP-synt_ab PF00006.20 KEP64020.1 - 0.017 14.5 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 KEP64020.1 - 0.02 14.0 0.1 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 KEP64020.1 - 0.033 14.3 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEP64020.1 - 0.073 12.5 0.2 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 KEP64020.1 - 0.077 11.8 0.0 0.2 10.5 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 KEP64020.1 - 0.1 12.9 0.0 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KEP64020.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KEP64020.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain UQ_con PF00179.21 KEP64022.1 - 4.6e-43 146.0 0.0 6.2e-43 145.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 KEP64022.1 - 2.1e-08 33.7 0.3 4.8e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Prok-E2_B PF14461.1 KEP64022.1 - 7.9e-06 25.6 0.0 1.7e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEP64022.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain UBA_2 PF08587.6 KEP64022.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) LSM PF01423.17 KEP64023.1 - 5.7e-05 22.5 0.0 7.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain HSA PF07529.8 KEP64024.1 - 0.0012 18.5 1.0 0.0012 18.5 0.7 2.6 2 0 0 2 2 2 1 HSA AnfO_nitrog PF09582.5 KEP64024.1 - 4.3 6.4 0.0 8.7 5.4 0.0 1.4 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) PAN_4 PF14295.1 KEP64027.1 - 7.4e-112 364.9 113.4 1.8e-11 43.5 1.4 15.8 15 0 0 15 15 15 15 PAN domain PAN_1 PF00024.21 KEP64027.1 - 1.2e-82 271.7 91.4 2.5e-06 27.1 0.1 15.5 15 1 1 16 16 16 15 PAN domain Pkinase PF00069.20 KEP64029.1 - 3.8e-11 42.6 0.0 6.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEP64029.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CwfJ_C_2 PF04676.9 KEP64031.1 - 4.1e-18 65.6 0.0 1e-17 64.4 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 KEP64031.1 - 3.3e-15 55.7 0.0 5.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MAT1 PF06391.8 KEP64035.1 - 8.8e-14 51.5 10.6 1.2e-13 51.1 7.4 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 KEP64035.1 - 0.00088 18.9 11.2 0.0015 18.2 7.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEP64035.1 - 0.00089 19.0 11.2 0.0014 18.4 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEP64035.1 - 0.0015 18.1 7.8 0.0024 17.4 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP64035.1 - 0.057 13.4 9.1 0.13 12.2 6.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP64035.1 - 0.061 12.9 8.3 0.22 11.2 5.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KEP64035.1 - 0.23 11.0 7.8 0.49 10.0 5.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 KEP64035.1 - 0.51 10.0 4.0 0.95 9.1 2.8 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-4CXXC_R1 PF10497.4 KEP64035.1 - 0.77 9.9 8.2 0.18 11.9 0.6 2.2 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DnaJ PF00226.26 KEP64036.1 - 2.4e-06 27.1 0.0 7.3e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L18p PF00861.17 KEP64037.1 - 4e-39 133.5 0.3 4e-39 133.5 0.2 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KEP64037.1 - 2.8e-35 120.7 7.5 2.8e-35 120.7 5.2 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ferritin-like PF12902.2 KEP64037.1 - 0.1 12.1 1.7 0.16 11.5 1.2 1.3 1 0 0 1 1 1 0 Ferritin-like CHORD PF04968.7 KEP64038.1 - 3.9e-54 180.7 23.5 6.2e-27 93.6 4.0 2.2 2 0 0 2 2 2 2 CHORD MFS_1 PF07690.11 KEP64040.1 - 9.7e-17 60.6 8.6 2.4e-16 59.4 5.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ABM PF03992.11 KEP64041.1 - 0.016 15.2 0.6 0.049 13.6 0.4 1.8 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DUF2431 PF10354.4 KEP64042.1 - 2.2e-05 24.5 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CDC45 PF02724.9 KEP64042.1 - 7.6 4.4 4.3 11 3.9 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L35p PF01632.14 KEP64043.1 - 0.0069 16.2 3.1 0.013 15.3 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L35 eIF3g PF12353.3 KEP64043.1 - 0.29 11.0 3.6 0.47 10.3 2.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G HEAT_2 PF13646.1 KEP64044.1 - 0.019 15.2 3.1 0.088 13.1 0.2 3.2 2 1 1 3 3 3 0 HEAT repeats Adaptin_N PF01602.15 KEP64044.1 - 0.27 9.5 0.0 4.8 5.3 0.0 2.2 2 1 0 2 2 2 0 Adaptin N terminal region Peptidase_S8 PF00082.17 KEP64046.1 - 5.5e-15 55.2 1.7 9.3e-15 54.5 1.2 1.3 1 0 0 1 1 1 1 Subtilase family Fcf1 PF04900.7 KEP64048.1 - 4.3e-38 129.4 1.2 5.6e-38 129.0 0.8 1.2 1 0 0 1 1 1 1 Fcf1 SNARE PF05739.14 KEP64049.1 - 2.6e-09 36.6 13.5 1.4e-07 31.1 5.6 2.4 2 0 0 2 2 2 2 SNARE domain V-SNARE_C PF12352.3 KEP64049.1 - 1.5e-08 34.5 16.0 2.6e-06 27.4 0.2 2.9 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEP64049.1 - 0.0011 18.6 3.5 0.0089 15.7 0.2 2.3 2 0 0 2 2 2 1 Sec20 NPV_P10 PF05531.7 KEP64049.1 - 0.035 14.3 10.3 0.06 13.5 0.6 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Flagellin_N PF00669.15 KEP64049.1 - 0.042 13.6 7.2 0.13 12.0 0.2 2.4 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF948 PF06103.6 KEP64049.1 - 0.071 12.9 4.1 0.49 10.2 0.6 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.7 KEP64049.1 - 0.75 9.8 6.3 1.3 9.1 1.0 3.0 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Caudo_TAP PF02413.12 KEP64049.1 - 1.1 9.4 7.1 0.12 12.5 1.0 2.1 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein DUF1664 PF07889.7 KEP64049.1 - 1.1 9.0 4.8 2.6 7.8 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 KEP64049.1 - 2.4 7.8 7.7 6.1 6.6 1.2 2.3 2 0 0 2 2 2 0 Laminin Domain II SlyX PF04102.7 KEP64049.1 - 2.5 8.5 10.9 1.1 9.6 3.2 2.8 2 0 0 2 2 2 0 SlyX SAPS PF04499.10 KEP64050.1 - 1.4e-08 33.8 16.0 0.00017 20.4 8.5 4.4 3 2 0 3 3 3 2 SIT4 phosphatase-associated protein 2-oxoacid_dh PF00198.18 KEP64052.1 - 1.7e-69 233.6 0.1 2.3e-69 233.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEP64052.1 - 1e-17 63.5 0.2 1.9e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEP64052.1 - 2.7e-15 55.7 0.2 9.1e-15 54.0 0.0 2.0 2 0 0 2 2 2 1 e3 binding domain GCV_H PF01597.14 KEP64052.1 - 0.0065 16.1 0.1 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 KEP64052.1 - 0.012 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like HlyD_2 PF12700.2 KEP64052.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein STAT_bind PF02864.10 KEP64052.1 - 0.2 11.2 0.2 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 STAT protein, DNA binding domain WD40 PF00400.27 KEP64053.1 - 4.4e-09 35.8 8.1 4.4e-06 26.3 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat SAPS PF04499.10 KEP64055.1 - 0.19 10.3 2.5 0.21 10.1 1.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KEP64055.1 - 0.35 8.8 9.4 0.4 8.6 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM75 PF14650.1 KEP64055.1 - 0.57 9.5 3.1 0.72 9.1 2.1 1.1 1 0 0 1 1 1 0 FAM75 family PPP4R2 PF09184.6 KEP64055.1 - 9.4 5.6 16.3 13 5.2 11.3 1.1 1 0 0 1 1 1 0 PPP4R2 MORN PF02493.15 KEP64056.1 - 2.9e-30 102.1 60.1 1.9e-05 24.0 0.1 12.8 14 0 0 14 14 14 11 MORN repeat Avl9 PF09794.4 KEP64056.1 - 1.1e-22 80.1 0.1 3.5e-07 29.0 0.0 3.7 3 1 1 4 4 4 3 Transport protein Avl9 DENN PF02141.16 KEP64056.1 - 0.0011 18.6 1.3 0.0058 16.3 0.1 2.5 3 0 0 3 3 3 1 DENN (AEX-3) domain UQ_con PF00179.21 KEP64057.1 - 8.4e-53 177.5 0.0 1.1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEP64057.1 - 6.7e-06 25.8 0.0 9.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEP64057.1 - 0.0012 18.6 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KEP64057.1 - 0.03 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain DNA_pol_B_exo1 PF03104.14 KEP64058.1 - 1.1e-40 139.5 0.0 2e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KEP64058.1 - 1.5e-16 60.3 6.1 7.9e-16 57.8 3.9 2.4 2 1 0 2 2 2 1 DNA polymerase family B DUF1744 PF08490.7 KEP64058.1 - 5.8e-14 51.4 0.0 1.9e-12 46.4 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1744) DNA_pol_B_exo2 PF10108.4 KEP64058.1 - 1.1e-05 25.0 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KEP64058.1 - 0.0049 16.6 0.0 0.019 14.7 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily RRM_5 PF13893.1 KEP64059.1 - 5.9e-09 35.6 0.0 9.7e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP64059.1 - 3.5e-06 26.5 0.0 0.0056 16.2 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64059.1 - 0.00011 22.1 0.0 0.084 12.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF791 PF05631.9 KEP64060.1 - 4.1e-56 190.1 2.4 1.6e-44 152.0 0.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF791) MFS_1 PF07690.11 KEP64060.1 - 3.2e-22 78.7 2.9 3.2e-22 78.7 2.0 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF842 PF05811.8 KEP64061.1 - 3.1e-18 65.4 12.0 3.5e-18 65.3 8.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1220 PF06758.8 KEP64061.1 - 0.029 14.1 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) zf-Tim10_DDP PF02953.10 KEP64061.1 - 9.5 5.5 16.3 0.13 11.6 2.0 3.4 1 1 1 2 2 2 0 Tim10/DDP family zinc finger DUF2036 PF09724.4 KEP64062.1 - 1.3e-08 34.3 0.0 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) Ctf8 PF09696.5 KEP64062.1 - 0.037 13.8 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Ctf8 Kinesin PF00225.18 KEP64063.1 - 5.8e-82 275.0 0.0 4.9e-81 272.0 0.0 2.3 1 1 0 1 1 1 1 Kinesin motor domain SlyX PF04102.7 KEP64063.1 - 2.8 8.3 16.7 0.63 10.4 0.3 5.4 4 1 0 4 4 4 0 SlyX Pkinase PF00069.20 KEP64064.1 - 4.3e-66 222.7 0.0 4.9e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64064.1 - 1.3e-39 135.8 0.0 1.6e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP64064.1 - 3.8e-07 29.3 0.0 3.8e-06 26.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KEP64064.1 - 0.00045 20.0 0.1 0.15 11.7 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEP64064.1 - 0.035 12.9 0.1 0.044 12.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase BTK PF00779.14 KEP64065.1 - 0.043 13.4 10.5 0.043 13.4 7.3 3.0 4 0 0 4 4 4 0 BTK motif Cytochrom_CIII PF02085.11 KEP64065.1 - 0.1 12.6 10.5 0.12 12.4 7.3 1.1 1 0 0 1 1 1 0 Class III cytochrome C family FKBP_C PF00254.23 KEP64066.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Laminin_G_2 PF02210.19 KEP64067.1 - 0.0053 16.7 0.0 0.0079 16.2 0.0 1.2 1 0 0 1 1 1 1 Laminin G domain MMtag PF10159.4 KEP64068.1 - 1.2e-16 60.5 2.2 1.2e-16 60.5 1.5 3.1 2 0 0 2 2 2 1 Kinase phosphorylation protein SET PF00856.23 KEP64069.1 - 4.5e-08 33.5 0.1 6.3e-05 23.3 0.0 2.8 3 0 0 3 3 3 2 SET domain Rubis-subs-bind PF09273.6 KEP64069.1 - 1e-07 31.9 0.0 2.8e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding CBF PF03914.12 KEP64070.1 - 1.3e-20 73.4 0.8 8.6e-20 70.8 0.5 2.5 1 1 0 1 1 1 1 CBF/Mak21 family RNase_PH PF01138.16 KEP64071.1 - 1.7e-27 96.3 0.0 5.6e-27 94.6 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 DUF1086 PF06461.6 KEP64074.1 - 0.056 13.2 0.3 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Bestrophin PF01062.16 KEP64075.1 - 5.5e-21 74.7 1.9 6.7e-21 74.4 1.3 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.20 KEP64076.1 - 2.4e-26 92.4 0.0 1.6e-25 89.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64076.1 - 7.3e-13 48.1 0.1 2.4e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RWD PF05773.17 KEP64076.1 - 6e-05 22.9 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 RWD domain DUF866 PF05907.8 KEP64076.1 - 1.1 8.7 0.0 2.3 7.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Mec-17 PF05301.6 KEP64077.1 - 6.9e-33 113.1 0.0 1.3e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 DUF515 PF04415.7 KEP64077.1 - 4.3 5.4 8.1 10 4.2 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AAA_12 PF13087.1 KEP64078.1 - 4.6e-33 114.2 0.0 8.3e-23 80.8 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KEP64078.1 - 7.8e-16 58.3 0.0 7.8e-16 58.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2439 PF10382.4 KEP64078.1 - 2e-06 27.9 0.3 6.3e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.13 KEP64078.1 - 0.00035 20.1 1.3 1.7 8.0 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KEP64078.1 - 0.0028 17.3 0.1 0.0094 15.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain EGF_3 PF12947.2 KEP64080.1 - 2e-07 30.8 27.0 3.7e-07 29.9 9.1 6.5 6 1 0 6 6 6 3 EGF domain cEGF PF12662.2 KEP64080.1 - 0.019 14.6 1.7 0.019 14.6 1.1 7.9 7 1 0 7 7 7 0 Complement Clr-like EGF-like Transposase_23 PF03017.9 KEP64080.1 - 0.16 11.5 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 TNP1/EN/SPM transposase UPF0016 PF01169.14 KEP64081.1 - 1.5e-41 140.4 21.2 8.7e-23 80.2 4.2 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 EF-hand_1 PF00036.27 KEP64082.1 - 0.00019 20.4 0.6 0.96 8.9 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KEP64082.1 - 0.0004 20.4 1.6 0.003 17.6 0.4 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEP64082.1 - 0.0031 17.2 1.3 1.6 8.8 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KEP64082.1 - 0.05 13.2 0.4 1.6 8.3 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain pair RRM_1 PF00076.17 KEP64083.1 - 7.1e-27 92.8 0.0 9.4e-16 57.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64083.1 - 1.5e-19 69.7 0.0 1.6e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64083.1 - 7.2e-09 35.3 0.0 0.00018 21.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CECR6_TMEM121 PF14997.1 KEP64086.1 - 1.8e-15 57.0 2.9 1.8e-15 57.0 2.0 2.1 1 1 1 2 2 2 1 CECR6/TMEM121 family SAG PF04092.8 KEP64090.1 - 1.6e-09 38.1 0.0 0.00013 22.3 0.0 2.3 2 0 0 2 2 2 2 SRS domain Kelch_5 PF13854.1 KEP64093.1 - 6.2e-16 57.9 2.9 4.2e-05 23.3 0.0 3.5 3 1 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 KEP64093.1 - 1.9e-15 56.5 12.2 0.014 15.5 0.1 5.3 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KEP64093.1 - 2.3e-13 49.3 9.7 1.2e-05 24.9 0.0 3.9 3 2 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 KEP64093.1 - 1e-12 47.3 5.7 0.0015 18.0 0.2 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 KEP64093.1 - 5.2e-10 38.9 17.8 1.1e-05 25.1 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KEP64093.1 - 6e-06 26.2 10.6 0.48 10.6 0.1 4.9 4 2 2 6 6 6 2 Kelch motif RAG2 PF03089.9 KEP64093.1 - 0.00029 19.6 0.0 0.41 9.3 0.0 3.0 3 0 0 3 3 3 2 Recombination activating protein 2 YHS PF04945.8 KEP64096.1 - 0.00046 19.9 0.3 4.5 7.2 0.0 3.4 3 0 0 3 3 3 2 YHS domain DUF3508 PF12018.3 KEP64096.1 - 0.097 11.6 0.0 2.3 7.1 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3508) Mus7 PF09462.5 KEP64096.1 - 0.35 9.6 3.7 1.6 7.5 0.7 2.4 2 0 0 2 2 2 0 Mus7/MMS22 family DUF4435 PF14491.1 KEP64096.1 - 0.78 9.5 0.0 2.4 7.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4435) Iron_permease PF04120.7 KEP64096.1 - 2.1 7.9 2.6 16 5.0 1.8 2.7 1 0 0 1 1 1 0 Low affinity iron permease Gaa1 PF04114.9 KEP64097.1 - 2.2e-13 49.7 0.8 1.8e-11 43.4 0.1 2.8 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component DUF1510 PF07423.6 KEP64097.1 - 0.00026 20.4 1.3 0.00026 20.4 0.9 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1510) DUF912 PF06024.7 KEP64097.1 - 0.011 15.8 0.1 0.52 10.3 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2217 PF10265.4 KEP64099.1 - 0.033 12.9 8.3 0.054 12.2 5.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3584 PF12128.3 KEP64099.1 - 0.053 10.8 24.1 0.081 10.2 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Macoilin PF09726.4 KEP64099.1 - 2.6 6.2 14.3 4.5 5.4 9.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 KEP64101.1 - 2.8e-51 174.1 0.0 6.2e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64101.1 - 1.6e-28 99.4 0.0 3.9e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase SF-assemblin PF06705.6 KEP64102.1 - 5.7e-05 22.3 32.7 0.00054 19.1 17.4 3.3 1 1 1 2 2 2 1 SF-assemblin/beta giardin Macoilin PF09726.4 KEP64102.1 - 0.00013 20.4 29.3 0.00028 19.3 12.9 2.1 1 1 1 2 2 2 2 Transmembrane protein IL31 PF15209.1 KEP64102.1 - 0.0015 18.1 0.2 0.0031 17.0 0.1 1.5 1 0 0 1 1 1 1 Interleukin 31 DUF904 PF06005.7 KEP64102.1 - 0.029 14.6 5.9 0.029 14.6 4.1 5.0 3 1 2 5 5 5 0 Protein of unknown function (DUF904) FlaC_arch PF05377.6 KEP64102.1 - 0.035 14.0 6.8 0.37 10.7 0.0 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Na_Ala_symp PF01235.12 KEP64102.1 - 0.08 11.5 1.9 0.11 10.9 1.3 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family Duffy_binding PF05424.6 KEP64102.1 - 0.23 11.2 3.8 8.5 6.1 0.5 2.4 2 1 0 2 2 2 0 Duffy binding domain Baculo_PEP_C PF04513.7 KEP64102.1 - 0.65 9.8 9.8 4.1 7.2 2.4 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 KEP64102.1 - 3.5 4.8 35.6 7 3.8 24.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DeoC PF01791.4 KEP64103.1 - 7.8e-12 44.9 0.1 1.1e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF556 PF04476.8 KEP64103.1 - 0.14 11.3 1.8 1.3 8.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF556) Glycos_transf_2 PF00535.21 KEP64105.1 - 8.2e-23 80.9 0.0 1.4e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KEP64105.1 - 4.2e-16 59.1 0.1 6.6e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 KEP64105.1 - 1.3e-07 30.9 0.0 2.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KEP64105.1 - 1.3e-07 30.9 0.0 1.9e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 KEP64105.1 - 2.5e-05 24.1 0.0 4.7e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Ala_racemase_N PF01168.15 KEP64106.1 - 2.8e-33 115.3 4.9 8.7e-23 81.0 0.9 2.9 1 1 1 2 2 2 2 Alanine racemase, N-terminal domain DUF3719 PF12516.3 KEP64106.1 - 0.039 13.5 0.1 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) ABC_tran PF00005.22 KEP64108.1 - 1.4e-46 158.1 2.1 5.6e-23 81.7 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KEP64108.1 - 1.3e-21 76.2 0.3 1.3e-21 76.2 0.2 3.5 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 KEP64108.1 - 8.5e-19 68.5 6.4 1.4e-06 28.4 0.1 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 KEP64108.1 - 5.7e-08 32.2 6.0 0.0098 15.1 0.5 4.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEP64108.1 - 1.3e-07 31.0 0.5 0.023 14.2 0.1 3.2 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KEP64108.1 - 3.4e-07 29.6 0.3 0.82 8.6 0.0 4.2 4 0 0 4 4 4 3 AAA ATPase domain DUF258 PF03193.11 KEP64108.1 - 7.6e-07 28.4 0.4 0.007 15.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KEP64108.1 - 8.8e-07 29.4 0.0 0.062 13.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 KEP64108.1 - 3.3e-05 24.6 1.0 0.073 13.8 0.4 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KEP64108.1 - 7.4e-05 22.6 0.1 0.094 12.6 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KEP64108.1 - 0.00016 21.9 0.5 0.14 12.5 0.0 3.7 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.18 KEP64108.1 - 0.00037 20.3 1.8 0.46 10.2 0.0 2.8 3 0 0 3 3 2 2 Dynamin family AAA_22 PF13401.1 KEP64108.1 - 0.00041 20.4 0.4 2.3 8.3 0.2 3.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEP64108.1 - 0.00051 19.9 0.8 0.25 11.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KEP64108.1 - 0.0023 17.5 0.1 0.79 9.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 KEP64108.1 - 0.0027 17.1 0.4 0.64 9.3 0.0 3.5 3 1 1 4 4 4 1 AAA domain AAA_10 PF12846.2 KEP64108.1 - 0.0044 16.4 0.2 3.6 6.9 0.1 3.3 3 0 0 3 3 3 1 AAA-like domain ArgK PF03308.11 KEP64108.1 - 0.0052 15.6 0.4 0.81 8.4 0.0 2.4 2 0 0 2 2 2 1 ArgK protein MobB PF03205.9 KEP64108.1 - 0.0061 16.2 0.1 2.8 7.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KEP64108.1 - 0.01 15.3 0.3 0.11 11.9 0.0 2.2 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 KEP64108.1 - 0.012 15.4 0.1 6.7 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 KEP64108.1 - 0.014 15.2 2.5 0.9 9.5 0.0 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 KEP64108.1 - 0.018 13.9 0.6 1 8.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 KEP64108.1 - 0.025 14.2 0.1 3.5 7.3 0.0 2.7 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 KEP64108.1 - 0.028 13.9 0.1 3.5 7.0 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 KEP64108.1 - 0.03 13.2 0.2 4.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arf PF00025.16 KEP64108.1 - 0.039 13.1 0.2 3.3 6.9 0.0 2.8 3 0 0 3 3 2 0 ADP-ribosylation factor family AAA_28 PF13521.1 KEP64108.1 - 0.066 13.1 5.0 3.2 7.6 0.0 3.7 4 0 0 4 4 3 0 AAA domain G-alpha PF00503.15 KEP64108.1 - 0.067 11.8 0.0 0.16 10.6 0.0 1.6 1 0 0 1 1 1 0 G-protein alpha subunit RNA_helicase PF00910.17 KEP64108.1 - 0.067 13.3 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KEP64108.1 - 0.068 13.1 10.3 0.1 12.5 0.2 3.6 3 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.24 KEP64108.1 - 0.094 12.9 0.0 21 5.3 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 KEP64108.1 - 0.097 11.6 0.3 5.9 5.8 0.0 2.9 2 1 1 3 3 3 0 Septin DUF999 PF06198.6 KEP64108.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) cobW PF02492.14 KEP64108.1 - 0.16 11.4 0.7 20 4.5 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 KEP64108.1 - 0.58 9.9 7.6 2.6 7.8 0.2 3.2 4 0 0 4 4 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 KEP64108.1 - 2 8.6 16.9 0.52 10.6 0.1 3.9 5 0 0 5 5 3 0 AAA domain eIF-6 PF01912.13 KEP64109.1 - 5.6e-80 267.1 0.1 8.6e-80 266.5 0.1 1.3 1 0 0 1 1 1 1 eIF-6 family RRM_1 PF00076.17 KEP64110.1 - 1.8e-64 213.3 0.1 3.6e-16 58.5 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64110.1 - 2e-54 181.4 0.1 1.7e-17 63.1 0.0 5.9 5 1 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64110.1 - 6.6e-41 137.9 0.1 2.7e-13 49.5 0.0 5.7 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEP64110.1 - 4.5e-06 26.3 1.2 0.14 11.9 0.0 4.8 4 0 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 KEP64110.1 - 0.0029 17.3 0.0 2.9 7.7 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Smg4_UPF3 PF03467.10 KEP64110.1 - 0.032 14.2 0.0 0.4 10.6 0.0 2.8 3 0 0 3 3 3 0 Smg-4/UPF3 family SAP PF02037.22 KEP64110.1 - 0.033 13.6 0.1 3.7 7.1 0.0 2.6 2 0 0 2 2 2 0 SAP domain Usp PF00582.21 KEP64110.1 - 0.52 10.4 7.5 0.076 13.2 0.4 3.3 2 2 2 4 4 4 0 Universal stress protein family PDEase_I PF00233.14 KEP64111.1 - 5.4e-55 186.7 0.0 1.1e-54 185.7 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KEP64111.1 - 0.016 15.1 0.1 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 HD domain BRI3BP PF14965.1 KEP64111.1 - 0.1 11.9 1.6 3.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Negative regulator of p53/TP53 PP2C PF00481.16 KEP64112.1 - 1.5e-46 158.8 0.0 2.5e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEP64112.1 - 4.6e-08 32.9 0.1 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEP64112.1 - 1.3e-07 31.2 0.0 4.5e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PNTB PF02233.11 KEP64113.1 - 2.1e-191 636.7 18.9 2.1e-191 636.7 13.1 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KEP64113.1 - 1e-43 148.8 0.3 6.1e-43 146.2 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KEP64113.1 - 8.3e-34 116.5 0.0 2.3e-33 115.0 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KEP64113.1 - 1.2e-31 108.6 4.1 1.2e-31 108.6 2.8 4.5 3 1 2 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KEP64113.1 - 4.5e-06 25.9 0.1 0.048 12.8 0.0 3.0 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KEP64113.1 - 0.0088 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.17 KEP64113.1 - 0.024 14.3 0.1 0.36 10.5 0.1 2.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain AAA_11 PF13086.1 KEP64115.1 - 3.8e-84 281.9 0.0 2.8e-83 279.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KEP64115.1 - 1.4e-62 210.6 0.0 2.3e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP64115.1 - 1.2e-10 40.9 3.7 8.2e-07 28.6 0.2 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 KEP64115.1 - 3.1e-07 30.1 0.9 0.00061 19.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 KEP64115.1 - 3.4e-05 23.4 0.4 0.032 13.7 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 KEP64115.1 - 0.00065 19.9 0.1 0.0036 17.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KEP64115.1 - 0.0017 17.8 0.1 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 KEP64115.1 - 0.0023 16.8 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 KEP64115.1 - 0.011 15.8 0.5 0.097 12.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.16 KEP64115.1 - 0.011 15.0 0.0 0.56 9.4 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KEP64115.1 - 0.023 14.2 0.0 0.073 12.5 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.1 KEP64115.1 - 0.025 14.5 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KEP64115.1 - 0.027 14.8 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KEP64115.1 - 0.04 13.3 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KEP64115.1 - 0.055 13.0 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEP64115.1 - 0.092 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AP2 PF00847.15 KEP64116.1 - 1.7e-08 34.4 1.3 4.2e-08 33.2 0.9 1.6 1 0 0 1 1 1 1 AP2 domain ACDC PF14733.1 KEP64116.1 - 0.0036 17.4 0.0 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 AP2-coincident C-terminal Med8 PF10232.4 KEP64116.1 - 0.055 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DFP PF04127.10 KEP64117.1 - 1e-17 64.3 0.0 5.2e-07 29.4 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein ParA PF10609.4 KEP64118.1 - 2.6e-30 104.1 0.3 4.9e-30 103.2 0.2 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KEP64118.1 - 6.9e-19 68.0 0.0 1.2e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 KEP64118.1 - 7.6e-17 61.0 0.0 2.3e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF59 AAA_31 PF13614.1 KEP64118.1 - 2.3e-09 37.3 0.0 2.3e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF971 PF06155.7 KEP64118.1 - 8.2e-06 26.1 0.8 2.1e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF971) MipZ PF09140.6 KEP64118.1 - 3.6e-05 22.9 0.1 0.00016 20.8 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 KEP64118.1 - 0.00016 20.8 0.5 0.083 11.9 0.2 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase YhjQ PF06564.7 KEP64118.1 - 0.009 15.3 0.0 0.067 12.5 0.0 2.1 2 0 0 2 2 2 1 YhjQ protein Fer4_NifH PF00142.13 KEP64118.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 KEP64118.1 - 0.14 11.2 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein PGM_PMM_I PF02878.11 KEP64119.1 - 8.8e-38 128.9 0.1 1.8e-37 127.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KEP64119.1 - 9.8e-24 83.6 0.4 5.1e-23 81.3 0.2 2.2 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 KEP64119.1 - 7.9e-14 51.6 0.1 1.4e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 KEP64119.1 - 2.3e-07 30.7 0.0 7.2e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain BHD_3 PF10405.4 KEP64119.1 - 0.019 14.6 0.1 0.075 12.7 0.0 1.9 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 3 RPAP3_C PF13877.1 KEP64119.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Got1 PF04178.7 KEP64120.1 - 4.8e-31 107.3 18.0 7.4e-31 106.6 12.5 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3789 PF12664.2 KEP64120.1 - 2.8 7.3 10.9 0.76 9.1 1.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3789) BCDHK_Adom3 PF10436.4 KEP64121.1 - 9.7e-31 106.4 0.1 1.4e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEP64121.1 - 1.6e-18 66.4 0.0 5e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEP64121.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KEP64121.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain EGF_CA PF07645.10 KEP64123.1 - 6.8e-28 96.3 64.8 7.7e-10 38.6 4.9 6.6 6 0 0 6 6 6 4 Calcium-binding EGF domain cEGF PF12662.2 KEP64123.1 - 4.6e-19 67.7 44.4 5.4e-09 35.5 0.2 7.7 7 1 0 7 7 7 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP64123.1 - 5.4e-15 55.2 52.7 3.2e-07 30.3 3.9 6.3 6 0 0 6 6 6 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KEP64123.1 - 7.5e-09 35.4 47.9 0.00011 22.0 0.1 5.9 5 0 0 5 5 5 4 EGF domain EGF PF00008.22 KEP64123.1 - 6.2e-08 32.4 50.2 0.0072 16.2 1.7 6.2 6 0 0 6 6 6 5 EGF-like domain ATP-grasp_4 PF13535.1 KEP64124.1 - 0.055 13.1 0.1 14 5.3 0.0 4.1 4 0 0 4 4 4 0 ATP-grasp domain RasGEF PF00617.14 KEP64124.1 - 0.13 11.9 0.3 0.34 10.6 0.1 1.7 2 0 0 2 2 2 0 RasGEF domain AAA PF00004.24 KEP64125.1 - 2.8e-57 192.5 0.0 1.3e-40 138.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP64125.1 - 1.2e-12 48.1 3.4 0.0011 19.1 0.5 4.9 3 2 1 4 4 4 2 AAA domain AAA_16 PF13191.1 KEP64125.1 - 8.8e-12 45.3 0.0 7.5e-05 22.7 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 KEP64125.1 - 3e-10 40.1 0.0 0.0005 19.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KEP64125.1 - 1.9e-09 38.3 0.0 0.00056 20.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEP64125.1 - 2e-09 37.0 0.0 0.0019 17.9 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain TIP49 PF06068.8 KEP64125.1 - 7.2e-09 34.8 0.0 0.0016 17.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 KEP64125.1 - 1.2e-08 34.9 0.0 0.0056 16.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 KEP64125.1 - 2.1e-08 34.0 0.1 0.0027 17.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEP64125.1 - 8.7e-08 31.4 0.1 0.0029 16.6 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KEP64125.1 - 1.7e-07 31.5 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KEP64125.1 - 2.1e-07 31.0 0.0 4.6e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 KEP64125.1 - 8e-07 28.3 0.0 0.034 13.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 KEP64125.1 - 8.7e-07 28.5 0.0 0.063 12.7 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KEP64125.1 - 1.8e-06 27.4 1.2 0.15 11.4 0.0 4.1 2 2 2 4 4 4 2 AAA domain CDC48_N PF02359.13 KEP64125.1 - 2.3e-06 27.4 0.0 8.3e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.16 KEP64125.1 - 2.4e-06 26.8 0.3 0.025 13.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KEP64125.1 - 3.2e-06 26.9 0.0 0.015 14.9 0.0 3.4 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.17 KEP64125.1 - 5.7e-06 25.3 0.0 0.021 13.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.4 KEP64125.1 - 7.3e-06 25.1 0.0 0.011 14.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KEP64125.1 - 8.6e-06 25.8 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.1 KEP64125.1 - 1.2e-05 25.0 0.2 0.052 13.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 KEP64125.1 - 1.4e-05 24.3 0.0 0.0028 16.8 0.0 2.4 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.21 KEP64125.1 - 2.9e-05 23.6 0.0 0.27 10.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 KEP64125.1 - 4.2e-05 23.5 0.0 0.26 11.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 KEP64125.1 - 5.3e-05 23.0 0.3 1.3 8.6 0.0 3.7 2 1 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 KEP64125.1 - 0.00053 19.8 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KEP64125.1 - 0.00054 19.6 0.0 0.64 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KEP64125.1 - 0.001 18.6 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEP64125.1 - 0.0011 18.2 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein UPF0079 PF02367.12 KEP64125.1 - 0.0012 18.5 0.0 0.49 10.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 KEP64125.1 - 0.0012 19.1 0.0 0.43 10.8 0.0 2.5 2 0 0 2 2 2 1 ABC transporter KTI12 PF08433.5 KEP64125.1 - 0.0029 16.8 0.0 2 7.5 0.0 2.6 3 0 0 3 3 2 1 Chromatin associated protein KTI12 AAA_30 PF13604.1 KEP64125.1 - 0.0034 17.0 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KEP64125.1 - 0.0059 16.6 0.0 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 KEP64125.1 - 0.0068 15.3 0.1 0.33 9.8 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.14 KEP64125.1 - 0.0088 15.5 0.1 0.86 9.0 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Bac_DnaA PF00308.13 KEP64125.1 - 0.0093 15.6 0.0 2.1 7.9 0.0 3.1 4 0 0 4 4 4 1 Bacterial dnaA protein Parvo_NS1 PF01057.12 KEP64125.1 - 0.01 14.7 0.0 0.85 8.4 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CPT PF07931.7 KEP64125.1 - 0.016 14.8 0.0 0.088 12.4 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 KEP64125.1 - 0.038 13.7 0.0 7 6.3 0.0 2.7 2 0 0 2 2 2 0 NTPase KAP_NTPase PF07693.9 KEP64125.1 - 0.042 12.8 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain TrwB_AAD_bind PF10412.4 KEP64125.1 - 0.046 12.3 0.0 2.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.7 KEP64125.1 - 0.053 12.9 0.0 7.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) IPT PF01745.11 KEP64125.1 - 0.057 12.5 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.6 KEP64125.1 - 0.076 12.9 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Torsin AAA_10 PF12846.2 KEP64125.1 - 0.077 12.4 0.0 8.9 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain SKI PF01202.17 KEP64125.1 - 0.081 12.7 1.4 7.6 6.3 0.0 3.0 3 1 0 3 3 2 0 Shikimate kinase T2SE PF00437.15 KEP64125.1 - 0.084 11.7 0.0 3.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 KEP64125.1 - 0.11 12.1 0.0 7.7 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KEP64125.1 - 0.13 11.7 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CPW_WPC PF09717.5 KEP64126.1 - 8.9e-34 115.9 17.3 8.1e-17 61.5 4.4 2.2 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) RNA_Me_trans PF04252.8 KEP64127.1 - 3.2e-32 111.5 0.0 3.6e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase SNF2_N PF00176.18 KEP64128.1 - 5.2e-64 215.8 0.0 8e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain UBA_4 PF14555.1 KEP64128.1 - 4.9e-10 38.7 0.0 1.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain zf-C3HC4_3 PF13920.1 KEP64128.1 - 1.3e-08 34.3 11.4 3e-08 33.2 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP64128.1 - 8.6e-08 32.0 14.2 1.8e-07 31.0 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP64128.1 - 1e-06 28.2 13.0 3.1e-06 26.7 9.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP64128.1 - 5.5e-06 26.0 10.9 1.4e-05 24.6 7.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEP64128.1 - 5.8e-06 26.0 13.2 1.3e-05 24.8 9.2 1.7 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 KEP64128.1 - 7.5e-06 25.7 0.0 3e-05 23.7 0.0 2.1 2 1 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 KEP64128.1 - 0.0069 16.2 13.4 0.017 14.9 9.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING UBA PF00627.26 KEP64128.1 - 0.0083 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Haem_bd PF14376.1 KEP64128.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Haem-binding domain zf-RING_6 PF14835.1 KEP64128.1 - 0.47 10.2 5.6 1.1 9.0 3.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KEP64128.1 - 1.2 8.7 6.8 2.7 7.5 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit E1-E2_ATPase PF00122.15 KEP64130.1 - 5.7e-20 71.3 0.0 1.7e-19 69.7 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEP64130.1 - 1.6e-15 58.0 0.0 3.5e-07 30.8 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP64130.1 - 3.1e-15 56.8 0.0 1.1e-14 55.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_2 PF13923.1 KEP64131.1 - 2e-09 37.3 13.5 2e-09 37.3 9.4 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP64131.1 - 3.5e-08 32.9 13.7 3.5e-08 32.9 9.5 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.13 KEP64131.1 - 5.2e-08 33.1 1.0 5.2e-08 33.1 0.7 4.1 3 1 1 4 4 4 1 TRAF-type zinc finger zf-RING_2 PF13639.1 KEP64131.1 - 5.9e-07 29.2 13.1 5.9e-07 29.2 9.1 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEP64131.1 - 9.4e-07 28.4 10.5 9.4e-07 28.4 7.3 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEP64131.1 - 3.3e-06 26.8 14.1 3.3e-06 26.8 9.8 3.2 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KEP64131.1 - 3.4e-05 23.4 11.9 3.4e-05 23.4 8.2 3.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEP64131.1 - 5.3e-05 22.8 6.1 5.3e-05 22.8 4.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger Cut8_N PF14482.1 KEP64131.1 - 0.13 12.2 0.8 0.26 11.3 0.6 1.4 1 0 0 1 1 1 0 Cut8 proteasome-binding domain DUF3138 PF11336.3 KEP64131.1 - 0.14 10.3 1.5 0.19 9.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Helicase_C PF00271.26 KEP64132.1 - 6.7e-14 51.5 0.1 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 KEP64132.1 - 1.3e-11 44.3 0.2 3.8e-11 42.8 0.2 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 KEP64132.1 - 8.8e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEP64132.1 - 0.00067 19.8 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KEP64132.1 - 0.95 8.5 0.0 1.7 7.6 0.0 1.3 1 0 0 1 1 1 0 KaiC Ldh_1_N PF00056.18 KEP64133.1 - 1.7e-40 138.0 0.1 2.6e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEP64133.1 - 1.2e-34 119.5 0.0 1.7e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 KEP64133.1 - 1.7e-05 24.1 1.1 0.019 14.2 0.1 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.9 KEP64133.1 - 0.014 14.7 0.9 0.086 12.2 0.6 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 KEP64133.1 - 0.036 14.5 1.2 0.12 12.7 0.5 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_S16 PF00886.14 KEP64134.1 - 1e-15 57.1 0.0 2.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S16 DUF2774 PF11242.3 KEP64134.1 - 0.12 12.3 0.3 0.27 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Cpn60_TCP1 PF00118.19 KEP64135.1 - 5.9e-151 503.3 0.0 6.7e-151 503.2 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2946 PF11162.3 KEP64140.1 - 0.06 13.5 3.4 0.072 13.2 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2946) PUF PF00806.14 KEP64141.1 - 6.7e-40 132.3 0.0 1.9e-07 30.2 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CAF-1_p150 PF11600.3 KEP64142.1 - 0.28 10.5 7.5 0.53 9.6 5.2 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tmemb_cc2 PF10267.4 KEP64142.1 - 1.1 7.7 3.5 1.3 7.4 2.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MOZ_SAS PF01853.13 KEP64143.1 - 2.3e-71 238.9 0.1 3.2e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KEP64143.1 - 4.1e-10 39.2 0.0 9.9e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_AsnC-type PF13404.1 KEP64143.1 - 0.05 13.1 0.3 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Acetyltransf_7 PF13508.1 KEP64143.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C5HC2 PF02928.11 KEP64143.1 - 5.3 7.1 7.9 2.8 8.0 0.1 3.0 3 0 0 3 3 3 0 C5HC2 zinc finger CLP_protease PF00574.18 KEP64144.1 - 4.3e-32 111.2 0.0 5.5e-20 71.8 0.0 3.1 3 0 0 3 3 3 3 Clp protease Transketolase_N PF00456.16 KEP64145.1 - 2.6e-136 453.8 0.0 5e-136 452.8 0.0 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KEP64145.1 - 1.2e-32 112.8 0.0 2.6e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KEP64145.1 - 9.7e-08 31.2 0.0 7.5e-06 25.0 0.0 2.5 2 1 1 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 KEP64145.1 - 3.1e-06 27.1 0.0 1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 KEP64145.1 - 0.0025 17.4 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pcc1 PF09341.5 KEP64145.1 - 0.058 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Transcription factor Pcc1 PDZ_2 PF13180.1 KEP64146.1 - 2e-13 49.9 0.0 3.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.1 KEP64146.1 - 1.4e-08 34.7 0.0 9.5e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 KEP64146.1 - 6.3e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) FKBP_C PF00254.23 KEP64147.1 - 1.8e-12 47.0 0.0 3.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.13 KEP64147.1 - 1.4e-05 25.1 2.1 1.7e-05 24.8 0.0 2.3 3 0 0 3 3 3 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase WD40 PF00400.27 KEP64148.1 - 5.8e-23 79.8 17.5 8.1e-05 22.3 0.2 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KEP64148.1 - 1.4e-05 25.1 0.1 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit UDP-g_GGTase PF06427.6 KEP64148.1 - 1.6 7.9 3.3 2.6 7.3 2.3 1.2 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase TTL PF03133.10 KEP64149.1 - 2.8e-54 184.0 0.1 6.1e-53 179.6 0.0 2.5 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEP64149.1 - 5e-05 22.2 0.0 0.00019 20.3 0.0 1.8 2 0 0 2 2 2 1 YheC/D like ATP-grasp CP_ATPgrasp_1 PF04174.8 KEP64149.1 - 0.33 9.5 0.0 0.56 8.7 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp PGK PF00162.14 KEP64150.1 - 1e-145 485.1 0.5 1.1e-145 484.9 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase His_Phos_1 PF00300.17 KEP64153.1 - 3.7e-26 92.1 0.1 1.9e-25 89.7 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pex16 PF08610.5 KEP64154.1 - 3e-07 29.7 0.0 3.9e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Fe-S_biosyn PF01521.15 KEP64155.1 - 0.00059 19.7 0.0 0.075 12.9 0.0 2.7 3 0 0 3 3 3 2 Iron-sulphur cluster biosynthesis Motile_Sperm PF00635.21 KEP64156.1 - 7.3e-22 77.0 0.0 1e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain HALZ PF02183.13 KEP64156.1 - 0.0047 16.6 2.8 0.0077 15.9 1.9 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF4187 PF13821.1 KEP64157.1 - 0.038 13.5 0.0 0.75 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) SART-1 PF03343.8 KEP64158.1 - 5.7e-69 233.0 96.5 5.3e-64 216.6 66.9 3.6 1 1 0 1 1 1 1 SART-1 family SET PF00856.23 KEP64161.1 - 5e-17 62.6 0.0 5e-17 62.6 0.0 3.5 3 2 0 3 3 3 1 SET domain AP2 PF00847.15 KEP64162.1 - 1.4e-07 31.5 3.1 1.4e-07 31.5 2.1 2.0 2 0 0 2 2 2 1 AP2 domain Pap_E4 PF02711.9 KEP64162.1 - 0.2 12.4 0.1 0.2 12.4 0.1 4.5 3 0 0 3 3 3 0 E4 protein TB2_DP1_HVA22 PF03134.14 KEP64164.1 - 1.3e-12 47.2 3.7 2e-12 46.6 2.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ABC2_membrane_3 PF12698.2 KEP64164.1 - 0.45 9.4 5.3 0.58 9.1 3.7 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein SAC3_GANP PF03399.11 KEP64165.1 - 2e-16 60.1 0.3 4e-16 59.2 0.2 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2762 PF10960.3 KEP64166.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) AAA_12 PF13087.1 KEP64167.1 - 2.3e-54 183.8 0.0 3.9e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEP64167.1 - 4.5e-45 154.0 0.4 1.5e-44 152.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KEP64167.1 - 1.1e-15 57.1 0.2 1.8e-13 50.0 0.1 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 KEP64167.1 - 8.6e-11 41.7 0.0 8.6e-10 38.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain dsrm PF00035.20 KEP64167.1 - 1.3e-05 25.6 0.1 0.037 14.6 0.1 3.2 3 0 0 3 3 3 2 Double-stranded RNA binding motif NACHT PF05729.7 KEP64167.1 - 0.0003 20.4 0.0 0.00068 19.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.9 KEP64167.1 - 0.0003 19.8 0.0 0.0027 16.7 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase IstB_IS21 PF01695.12 KEP64167.1 - 0.0028 17.1 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 KEP64167.1 - 0.0036 17.3 0.0 0.03 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 KEP64167.1 - 0.0038 16.2 0.3 0.027 13.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KEP64167.1 - 0.0041 16.3 0.0 0.011 14.9 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.24 KEP64167.1 - 0.01 16.0 0.0 0.046 13.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEP64167.1 - 0.045 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KEP64167.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 KEP64167.1 - 0.07 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.1 KEP64167.1 - 0.17 12.0 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEP64167.1 - 0.19 11.1 0.0 0.53 9.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Thioredoxin PF00085.15 KEP64168.1 - 7.4e-62 205.5 4.8 1.2e-32 111.7 0.1 3.8 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 KEP64168.1 - 1.3e-36 126.1 4.8 1e-19 71.0 0.2 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KEP64168.1 - 4.3e-16 59.0 3.2 6.2e-07 29.6 0.1 4.5 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEP64168.1 - 1.6e-13 50.5 0.1 3e-05 24.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KEP64168.1 - 2.4e-11 43.4 1.2 4.4e-05 23.4 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 KEP64168.1 - 5.8e-10 38.8 1.9 0.00024 20.6 0.1 2.8 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 KEP64168.1 - 9.8e-10 38.1 0.5 2.1e-05 24.1 0.0 2.6 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 KEP64168.1 - 3.9e-09 35.7 1.7 8.2e-09 34.7 1.2 1.6 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_9 PF14595.1 KEP64168.1 - 1.7e-05 24.3 0.1 0.061 12.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.1 KEP64168.1 - 0.00013 21.5 0.0 0.034 13.6 0.0 2.9 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 KEP64168.1 - 0.00088 19.0 0.0 0.77 9.6 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KEP64168.1 - 0.0078 16.2 1.6 5.7 6.9 0.1 3.8 3 1 1 4 4 4 1 Thioredoxin Glutaredoxin PF00462.19 KEP64168.1 - 0.011 15.7 3.5 1.1 9.3 0.0 3.5 3 1 0 3 3 2 0 Glutaredoxin HyaE PF07449.6 KEP64168.1 - 0.05 13.4 0.0 2 8.3 0.0 3.0 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Sipho_Gp157 PF05565.6 KEP64169.1 - 0.01 15.4 6.8 0.018 14.5 4.7 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 Snapin_Pallidin PF14712.1 KEP64169.1 - 0.15 12.4 12.7 0.4 11.0 2.9 3.0 3 0 0 3 3 3 0 Snapin/Pallidin CENP-H PF05837.7 KEP64169.1 - 0.3 11.2 18.4 0.087 13.0 5.2 3.1 2 1 0 3 3 3 0 Centromere protein H (CENP-H) AAT PF03417.11 KEP64169.1 - 0.33 10.3 2.9 1.5 8.1 0.0 2.3 1 1 1 3 3 3 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase RTBV_P46 PF06216.6 KEP64169.1 - 0.48 9.2 3.6 0.27 10.0 1.2 1.4 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein IncA PF04156.9 KEP64169.1 - 3.2 7.2 28.7 7.1 6.1 19.9 1.6 1 1 0 1 1 1 0 IncA protein S1 PF00575.18 KEP64170.1 - 4.5e-26 90.7 1.6 1e-12 47.9 0.1 2.4 2 0 0 2 2 2 2 S1 RNA binding domain zf-CCHC_3 PF13917.1 KEP64170.1 - 1.2e-14 53.7 0.3 2.6e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle S1_2 PF13509.1 KEP64170.1 - 0.002 17.9 0.0 0.84 9.5 0.0 2.6 2 0 0 2 2 2 2 S1 domain zf-CCHC PF00098.18 KEP64170.1 - 0.0021 17.8 5.1 0.0043 16.9 3.5 1.6 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.4 KEP64170.1 - 0.023 14.1 39.8 0.044 13.2 27.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4604 PF15377.1 KEP64170.1 - 0.12 12.5 24.4 0.23 11.6 16.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Rtf2 PF04641.7 KEP64170.1 - 1.2 8.3 17.7 1.7 7.8 12.3 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FancD2 PF14631.1 KEP64170.1 - 4.7 4.1 14.3 6.4 3.7 9.9 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Vfa1 PF08432.5 KEP64170.1 - 5.5 6.9 21.9 9.4 6.2 15.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 KEP64170.1 - 7.7 4.4 18.5 10 3.9 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Harakiri PF15196.1 KEP64171.1 - 0.0095 16.1 0.4 0.024 14.8 0.3 1.7 1 0 0 1 1 1 1 Activator of apoptosis harakiri DUF3522 PF12036.3 KEP64173.1 - 1.5e-10 41.1 6.6 1.5e-10 41.1 4.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3522) DUF401 PF04165.7 KEP64173.1 - 3.6 6.4 2.6 5.2 5.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) DUF226 PF02890.9 KEP64176.1 - 1.2 8.8 0.1 2 8.1 0.1 1.2 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 MMR_HSR1 PF01926.18 KEP64177.1 - 2.2e-43 146.8 0.0 4.5e-21 74.9 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 KEP64177.1 - 2.7e-24 84.9 0.3 4.7e-24 84.1 0.2 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.22 KEP64177.1 - 1.7e-19 70.0 0.0 1.5e-08 34.3 0.1 4.3 5 0 0 5 5 5 3 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KEP64177.1 - 3.7e-17 62.0 0.0 1.1e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 KEP64177.1 - 1.6e-10 41.5 0.0 0.00043 20.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AIG1 PF04548.11 KEP64177.1 - 6.8e-07 28.6 0.0 0.024 13.7 0.0 2.3 2 0 0 2 2 2 2 AIG1 family DUF258 PF03193.11 KEP64177.1 - 4.3e-06 25.9 0.0 0.016 14.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEP64177.1 - 5.8e-06 26.2 0.0 0.4 10.4 0.0 3.6 3 1 1 4 4 4 2 Dynamin family ABC_tran PF00005.22 KEP64177.1 - 0.00015 22.0 0.0 3 8.1 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ArgK PF03308.11 KEP64177.1 - 0.0004 19.2 0.0 0.87 8.3 0.1 3.4 4 0 0 4 4 4 1 ArgK protein MCM PF00493.18 KEP64177.1 - 0.0031 16.3 0.0 0.024 13.4 0.0 2.0 2 0 0 2 2 2 1 MCM2/3/5 family SRPRB PF09439.5 KEP64177.1 - 0.011 15.0 0.0 5.9 6.0 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit cobW PF02492.14 KEP64177.1 - 0.011 15.1 1.6 0.63 9.4 0.2 3.4 2 2 2 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KEP64177.1 - 0.011 16.4 0.5 5.8 7.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 KEP64177.1 - 0.026 14.8 0.0 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 KEP64177.1 - 0.047 13.0 0.0 2.2 7.6 0.0 2.8 2 1 0 2 2 2 0 Ras family Arch_ATPase PF01637.13 KEP64177.1 - 0.048 13.3 0.0 16 5.1 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase AAA_22 PF13401.1 KEP64177.1 - 0.11 12.6 0.0 40 4.3 0.0 3.2 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEP64177.1 - 0.29 11.3 0.0 25 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Fcf2 PF08698.6 KEP64178.1 - 3.9e-14 52.4 0.0 1.6e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing RAP1 PF07218.6 KEP64178.1 - 7.1 4.5 10.9 9.7 4.1 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2370 PF10176.4 KEP64179.1 - 0.0055 16.0 0.4 0.071 12.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) PseudoU_synth_1 PF01416.15 KEP64180.1 - 1.2e-12 48.2 0.0 1.4e-05 25.4 0.0 4.2 3 1 0 3 3 3 3 tRNA pseudouridine synthase LRR_4 PF12799.2 KEP64182.1 - 3.2e-24 84.0 28.9 1.1e-08 34.4 2.2 4.4 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 KEP64182.1 - 2.1e-14 53.4 0.5 5.7e-14 52.0 0.3 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 KEP64182.1 - 4.1e-13 48.8 14.6 1.6e-07 30.9 1.5 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KEP64182.1 - 6.2e-06 25.5 17.4 0.19 11.8 0.7 5.8 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 KEP64182.1 - 2.7e-05 23.7 14.1 0.057 13.5 0.3 5.8 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 KEP64182.1 - 0.0049 16.8 10.2 18 6.1 0.1 6.2 6 0 0 6 6 6 1 Leucine rich repeat RRM_1 PF00076.17 KEP64183.1 - 2.7e-17 62.1 0.0 3.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64183.1 - 3.8e-11 42.8 0.0 5.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64183.1 - 2.7e-10 39.9 0.0 4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUI1 PF01253.17 KEP64184.1 - 2e-12 46.7 0.0 4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF966 PF06136.8 KEP64185.1 - 2.8 7.2 10.8 3.2 7.0 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DEAD PF00270.24 KEP64186.1 - 7.7e-22 77.5 0.0 5e-12 45.6 0.0 3.4 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP64186.1 - 3.8e-19 68.3 0.0 1.4e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP64186.1 - 3.1e-07 30.4 0.0 3.1e-07 30.4 0.0 3.6 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit ThiF PF00899.16 KEP64187.1 - 0.004 16.9 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family eIF2A PF08662.6 KEP64190.1 - 2.4e-06 27.3 0.1 0.037 13.7 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KEP64190.1 - 0.00041 19.8 0.0 0.026 14.0 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 KEP64190.1 - 0.00043 19.2 0.4 0.61 8.8 0.0 3.3 2 1 2 4 4 4 2 Coatomer WD associated region WD40 PF00400.27 KEP64190.1 - 0.0016 18.2 6.1 1.3 9.0 0.1 6.0 7 0 0 7 7 7 1 WD domain, G-beta repeat Clathrin PF00637.15 KEP64191.1 - 5.2e-10 39.0 10.8 0.15 11.6 0.0 6.3 4 1 3 7 7 7 4 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 KEP64191.1 - 7.3e-09 34.9 10.3 7e-08 31.6 0.6 2.4 2 0 0 2 2 2 2 Coatomer WD associated region TPR_7 PF13176.1 KEP64191.1 - 6.7e-05 22.4 22.2 0.95 9.4 0.1 8.6 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP64191.1 - 0.00052 19.5 27.9 0.044 13.4 0.1 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEP64191.1 - 0.00074 19.1 13.6 0.098 12.4 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP64191.1 - 0.0032 17.2 3.6 0.021 14.7 0.5 10.2 10 1 1 11 11 11 2 Tetratricopeptide repeat Nic96 PF04097.9 KEP64191.1 - 0.0049 15.0 5.6 0.25 9.3 0.0 3.6 2 1 0 2 2 2 1 Nup93/Nic96 TPR_12 PF13424.1 KEP64191.1 - 0.038 13.9 37.5 0.061 13.2 0.4 8.6 7 3 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEP64191.1 - 0.43 10.2 32.6 0.039 13.5 2.5 7.1 6 1 0 6 6 6 0 TPR repeat DZR PF12773.2 KEP64191.1 - 4.4 7.2 13.8 3.1e+02 1.2 9.6 3.0 1 1 0 1 1 1 0 Double zinc ribbon DUF21 PF01595.15 KEP64193.1 - 1e-30 106.3 0.4 1.8e-30 105.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KEP64193.1 - 9.6e-06 25.2 0.8 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 CBS domain Peptidase_M24 PF00557.19 KEP64195.1 - 5.6e-45 153.4 0.0 7.5e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 RCC1_2 PF13540.1 KEP64197.1 - 1.2e-11 43.9 8.3 4.1e-05 23.0 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KEP64197.1 - 8.3e-06 25.9 16.3 0.56 10.4 0.0 7.8 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat YbjQ_1 PF01906.12 KEP64198.1 - 4.2e-24 84.9 1.2 7e-24 84.2 0.9 1.4 1 0 0 1 1 1 1 Putative heavy-metal-binding Dicty_REP PF05086.7 KEP64200.1 - 0.038 11.7 6.3 0.053 11.2 4.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 KEP64200.1 - 3.6 7.3 10.1 1.8 8.3 2.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Big_5 PF13205.1 KEP64201.1 - 2.1e-07 31.4 0.1 0.024 15.2 0.1 4.6 4 0 0 4 4 4 1 Bacterial Ig-like domain DUF4381 PF14316.1 KEP64201.1 - 0.031 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RNA_pol_Rpb2_4 PF04566.8 KEP64201.1 - 0.12 12.2 0.3 0.33 10.8 0.2 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 SIT PF15330.1 KEP64201.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT MR_MLE_N PF02746.11 KEP64201.1 - 0.25 11.3 0.2 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SpoVS PF04232.7 KEP64201.1 - 2 8.0 1.2 5.2 6.7 0.8 1.6 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) Pkinase PF00069.20 KEP64202.1 - 2.9e-07 29.9 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEP64202.1 - 0.00021 20.3 0.0 0.001 18.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like PTH2 PF01981.11 KEP64204.1 - 7.4e-45 151.3 0.1 9.5e-45 151.0 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3311 PF11755.3 KEP64204.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) IF-2B PF01008.12 KEP64205.1 - 8.9e-41 139.7 0.0 1.7e-40 138.7 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF162 PF02589.10 KEP64205.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised ACR, YkgG family COG1556 ORC4_C PF14629.1 KEP64206.1 - 3.3e-05 23.3 0.2 0.0017 17.7 0.0 3.7 4 0 0 4 4 4 2 Origin recognition complex (ORC) subunit 4 C-terminus AAA_22 PF13401.1 KEP64206.1 - 0.00025 21.1 0.1 0.052 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEP64206.1 - 0.00048 20.1 9.8 0.0041 17.1 3.2 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KEP64206.1 - 0.0017 18.5 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEP64206.1 - 0.002 17.7 1.2 0.2 11.3 0.1 3.1 1 1 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 KEP64206.1 - 0.0021 17.2 0.6 0.0042 16.2 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KEP64206.1 - 0.004 16.8 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain DUF3987 PF13148.1 KEP64206.1 - 0.0091 14.5 1.6 0.012 14.2 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3987) DUF2155 PF09923.4 KEP64207.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF2009 PF09418.5 KEP64207.1 - 4 6.1 2.9 6.1 5.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Aminotran_5 PF00266.14 KEP64208.1 - 3.5e-78 262.9 0.0 8.2e-57 192.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEP64208.1 - 1.3e-08 34.3 0.0 3.2e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KEP64208.1 - 2.9e-05 23.2 0.0 7.3e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KEP64208.1 - 3.3e-05 22.5 0.0 4.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.24 KEP64210.1 - 1.6e-14 54.2 0.0 1.1e-13 51.5 0.0 2.4 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP64210.1 - 7.8e-05 22.8 0.1 0.0025 17.9 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEP64210.1 - 0.00027 21.7 0.2 0.0029 18.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain IQ PF00612.22 KEP64210.1 - 0.0014 18.0 0.9 0.0037 16.7 0.6 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif SKI PF01202.17 KEP64210.1 - 0.0021 17.9 0.0 0.054 13.3 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase RuvB_N PF05496.7 KEP64210.1 - 0.0021 17.1 0.0 0.0045 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KEP64210.1 - 0.0034 17.6 0.2 0.14 12.4 0.0 3.7 3 1 0 3 3 3 1 AAA domain Torsin PF06309.6 KEP64210.1 - 0.0051 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_33 PF13671.1 KEP64210.1 - 0.0069 16.2 1.1 0.02 14.7 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KEP64210.1 - 0.0094 15.9 5.6 0.01 15.8 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 KEP64210.1 - 0.021 13.9 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEP64210.1 - 0.021 14.9 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KEP64210.1 - 0.029 14.1 0.0 0.1 12.3 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 KEP64210.1 - 0.073 12.7 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEP64210.1 - 0.083 12.2 0.0 8 5.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KEP64210.1 - 0.09 12.8 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Sec61_beta PF03911.11 KEP64211.1 - 4.1e-20 71.2 0.0 5.1e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family DUF781 PF05612.7 KEP64212.1 - 0.065 11.9 0.1 0.094 11.3 0.0 1.1 1 0 0 1 1 1 0 Mouse protein of unknown function (DUF781) RRM_6 PF14259.1 KEP64213.1 - 2.9e-16 59.2 0.0 5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP64213.1 - 5.1e-16 58.0 0.0 8.1e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64213.1 - 9.7e-08 31.7 0.1 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3138 PF11336.3 KEP64213.1 - 0.0043 15.3 0.5 0.0058 14.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) Nup35_RRM_2 PF14605.1 KEP64213.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif LUC7 PF03194.10 KEP64217.1 - 3.4e-59 200.4 7.6 3.4e-59 200.4 5.3 2.2 2 0 0 2 2 2 1 LUC7 N_terminus Cauli_AT PF03233.8 KEP64217.1 - 0.081 12.6 1.0 0.17 11.6 0.7 1.5 1 0 0 1 1 1 0 Aphid transmission protein Tweety PF04906.8 KEP64217.1 - 0.38 9.1 0.9 0.54 8.6 0.7 1.1 1 0 0 1 1 1 0 Tweety DUF4404 PF14357.1 KEP64217.1 - 1.1 9.6 5.2 1.7 9.1 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SlyX PF04102.7 KEP64217.1 - 5.6 7.4 7.1 6 7.3 0.3 3.2 1 1 1 2 2 2 0 SlyX AAA PF00004.24 KEP64218.1 - 1.2e-14 54.6 0.0 1.9e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KEP64218.1 - 2.8e-13 49.6 0.0 6.6e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KEP64218.1 - 9.7e-13 48.0 0.0 1.1e-10 41.4 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 KEP64218.1 - 5.8e-08 32.0 0.3 1.1e-06 27.9 0.2 2.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KEP64218.1 - 4.8e-07 29.7 0.0 8.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP64218.1 - 1.1e-06 28.7 0.3 0.00059 19.8 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 KEP64218.1 - 2.8e-06 27.1 0.0 9.1e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 KEP64218.1 - 4.9e-06 25.5 0.0 0.0072 15.0 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KEP64218.1 - 9e-06 25.8 1.2 0.00076 19.6 0.8 2.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEP64218.1 - 1.5e-05 24.5 1.0 0.17 11.2 0.2 2.8 1 1 1 2 2 2 2 AAA-like domain Mg_chelatase PF01078.16 KEP64218.1 - 2.6e-05 23.4 0.1 0.00085 18.5 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEP64218.1 - 0.00019 21.1 0.0 0.00062 19.4 0.0 2.0 1 1 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 KEP64218.1 - 0.00035 20.1 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KEP64218.1 - 0.0018 17.7 0.3 0.067 12.6 0.1 2.6 2 1 1 3 3 3 1 DEAD/DEAH box helicase DNA_pol3_delta PF06144.8 KEP64218.1 - 0.0022 17.5 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 KEP64218.1 - 0.0022 17.5 1.1 0.063 12.7 0.0 2.6 1 1 1 2 2 2 1 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 KEP64218.1 - 0.0025 17.8 0.0 0.0061 16.6 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 KEP64218.1 - 0.0027 17.1 0.3 0.013 14.9 0.1 2.1 1 1 0 2 2 2 1 AAA domain MCM PF00493.18 KEP64218.1 - 0.0028 16.4 0.0 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family IstB_IS21 PF01695.12 KEP64218.1 - 0.0043 16.4 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 KEP64218.1 - 0.0057 16.2 0.0 0.0072 15.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KEP64218.1 - 0.0058 16.3 0.0 0.1 12.2 0.0 2.1 1 1 1 2 2 2 1 Archaeal ATPase SNF2_N PF00176.18 KEP64218.1 - 0.0079 15.0 0.2 4 6.1 0.0 2.9 1 1 0 3 3 3 1 SNF2 family N-terminal domain Viral_helicase1 PF01443.13 KEP64218.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KEP64218.1 - 0.02 14.6 0.7 4.5 6.9 0.0 3.0 1 1 1 2 2 2 0 NTPase AAA_33 PF13671.1 KEP64218.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEP64218.1 - 0.054 13.0 0.1 0.16 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEP64218.1 - 0.094 12.9 0.0 0.32 11.1 0.0 1.9 1 1 0 1 1 1 0 RNA helicase DUF815 PF05673.8 KEP64218.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Noelin-1 PF12308.3 KEP64219.1 - 0.11 12.2 1.8 7.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein cEGF PF12662.2 KEP64219.1 - 0.12 12.0 0.2 0.12 12.0 0.1 15.0 15 3 1 16 16 16 0 Complement Clr-like EGF-like CBM_14 PF01607.19 KEP64219.1 - 7.5 6.5 55.0 0.035 14.0 0.9 9.4 7 3 3 10 10 10 0 Chitin binding Peritrophin-A domain tRNA-synt_1d PF00750.14 KEP64220.1 - 5.3e-105 351.1 0.2 3.2e-96 322.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 KEP64220.1 - 2.3e-32 111.4 0.1 5.8e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KEP64220.1 - 7.1e-13 48.9 0.2 2e-12 47.4 0.1 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 KEP64220.1 - 0.012 14.7 0.1 0.029 13.4 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain SBP_bac_5 PF00496.17 KEP64220.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle tRNA-synt_1 PF00133.17 KEP64220.1 - 0.03 12.3 0.1 0.051 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Njmu-R1 PF15053.1 KEP64220.1 - 0.067 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family Octopine_DH PF02317.12 KEP64220.1 - 0.12 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain RIO1 PF01163.17 KEP64221.1 - 3.6e-50 169.9 0.0 1e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 RIO1 family Aha1_N PF09229.6 KEP64224.1 - 4.4e-47 159.3 3.9 1e-23 83.6 0.0 2.7 3 0 0 3 3 3 2 Activator of Hsp90 ATPase, N-terminal Macoilin PF09726.4 KEP64224.1 - 0.034 12.4 11.3 0.044 12.0 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1423 PF07227.6 KEP64224.1 - 0.14 10.7 11.9 0.2 10.2 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) APG6 PF04111.7 KEP64224.1 - 0.59 9.1 13.1 0.88 8.5 9.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 T2SF PF00482.18 KEP64224.1 - 2 8.3 8.0 3.4 7.5 5.6 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F PDDEXK_1 PF12705.2 KEP64224.1 - 2.5 7.3 7.5 3.4 6.9 4.5 1.8 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily Spc24 PF08286.6 KEP64224.1 - 6.6 6.4 8.7 13 5.5 6.0 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DHO_dh PF01180.16 KEP64225.1 - 1.4e-96 322.9 0.0 1.7e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KEP64225.1 - 0.083 11.7 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Evr1_Alr PF04777.8 KEP64226.1 - 1.6e-20 72.7 0.1 2.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family UCH PF00443.24 KEP64227.1 - 6.2e-35 120.6 0.0 3.3e-34 118.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP64227.1 - 0.00014 21.3 0.0 0.004 16.6 0.0 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YccV-like PF08755.6 KEP64228.1 - 6.5e-18 64.5 0.0 1.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH PF07915.8 KEP64228.1 - 3.7e-17 62.9 0.1 5.8e-08 33.4 0.0 3.2 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KEP64228.1 - 0.23 10.9 0.0 1.4 8.3 0.0 2.2 3 0 0 3 3 3 0 Glucosidase II beta subunit-like protein Peptidase_C26 PF07722.8 KEP64230.1 - 1.5e-26 93.1 0.0 1.3e-15 57.4 0.0 4.0 3 1 0 3 3 3 3 Peptidase C26 GATase PF00117.23 KEP64230.1 - 7.3e-08 32.0 0.1 9.7e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I tRNA-synt_2d PF01409.15 KEP64231.1 - 1.7e-32 112.5 0.1 1.3e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KEP64231.1 - 4.4e-19 68.4 0.0 2.4e-18 66.1 0.0 2.2 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain PepSY_TM_1 PF13172.1 KEP64232.1 - 0.044 13.5 0.2 0.075 12.8 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix AAA_2 PF07724.9 KEP64233.1 - 7.2e-27 94.3 0.5 2.2e-20 73.2 0.1 3.1 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEP64233.1 - 3.1e-16 59.7 1.4 6.4e-07 29.6 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEP64233.1 - 1.8e-08 34.1 0.2 3.6e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEP64233.1 - 1.6e-06 28.2 0.2 1.2e-05 25.3 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEP64233.1 - 7.5e-06 26.1 0.2 0.0031 17.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain MCM PF00493.18 KEP64233.1 - 1e-05 24.5 0.0 0.0031 16.3 0.0 2.2 2 0 0 2 2 2 2 MCM2/3/5 family ClpB_D2-small PF10431.4 KEP64233.1 - 1.8e-05 24.5 0.2 5.7e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 KEP64233.1 - 0.00011 22.9 0.0 0.00035 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP64233.1 - 0.00056 19.8 0.2 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEP64233.1 - 0.00076 19.1 0.0 0.31 10.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 KEP64233.1 - 0.00088 18.4 0.6 0.0063 15.6 0.0 2.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEP64233.1 - 0.0023 17.9 3.5 0.0046 16.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KEP64233.1 - 0.003 17.4 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEP64233.1 - 0.0035 16.4 0.1 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEP64233.1 - 0.0044 16.4 0.3 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEP64233.1 - 0.0085 16.4 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEP64233.1 - 0.0098 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KEP64233.1 - 0.011 14.5 0.1 0.025 13.2 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus PduV-EutP PF10662.4 KEP64233.1 - 0.011 15.2 0.1 0.13 11.7 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 KEP64233.1 - 0.014 15.0 0.0 0.053 13.2 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 KEP64233.1 - 0.02 13.9 0.0 0.049 12.7 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.10 KEP64233.1 - 0.031 12.9 0.0 0.085 11.5 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 KEP64233.1 - 0.076 13.3 0.1 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 KEP64233.1 - 0.08 12.9 0.1 0.46 10.5 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF258 PF03193.11 KEP64233.1 - 0.08 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEP64233.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATG_C PF09333.6 KEP64234.1 - 8e-06 25.9 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 KEP64234.1 - 3.5e-05 23.3 0.0 0.00098 18.6 0.0 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ribosomal_S6e PF01092.14 KEP64235.1 - 2.7e-52 175.7 0.4 2.7e-52 175.7 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Ribosomal_L19e PF01280.15 KEP64236.1 - 9.6 5.9 6.9 6.4 6.5 4.2 1.2 1 1 0 1 1 1 0 Ribosomal protein L19e E1-E2_ATPase PF00122.15 KEP64237.1 - 5.8e-48 162.9 0.1 5.8e-48 162.9 0.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KEP64237.1 - 3.9e-24 86.2 0.1 2.6e-23 83.5 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEP64237.1 - 9.4e-15 53.8 0.0 2.2e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEP64237.1 - 1.3e-13 51.5 0.0 2.9e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEP64237.1 - 0.00017 21.2 6.4 0.0021 17.7 0.4 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP64237.1 - 0.00031 20.6 0.1 0.0078 16.1 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Noc2 PF03715.8 KEP64237.1 - 0.086 11.6 0.1 0.15 10.8 0.1 1.3 1 0 0 1 1 1 0 Noc2p family IF-2B PF01008.12 KEP64239.1 - 1.2e-43 149.1 0.0 4e-43 147.4 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family FAD_oxidored PF12831.2 KEP64239.1 - 0.0092 15.0 0.1 0.014 14.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DivIC PF04977.10 KEP64243.1 - 0.0036 16.7 1.6 0.0036 16.7 1.1 14.8 9 4 6 15 15 15 8 Septum formation initiator EMP24_GP25L PF01105.19 KEP64243.1 - 0.21 11.2 0.0 0.21 11.2 0.0 6.1 5 2 1 6 6 6 0 emp24/gp25L/p24 family/GOLD HALZ PF02183.13 KEP64244.1 - 3.6e-09 36.2 164.7 0.0042 16.7 2.7 20.6 22 0 0 22 22 22 14 Homeobox associated leucine zipper bZIP_1 PF00170.16 KEP64244.1 - 0.0012 18.7 12.6 0.0026 17.6 1.7 20.5 20 2 2 22 22 22 10 bZIP transcription factor Uds1 PF15456.1 KEP64244.1 - 0.023 14.6 0.2 0.023 14.6 0.2 12.2 10 5 1 11 11 11 0 Up-regulated During Septation ELMO_CED12 PF04727.8 KEP64247.1 - 6.4e-24 84.3 0.0 1.2e-23 83.5 0.0 1.5 1 1 0 1 1 1 1 ELMO/CED-12 family DUF581 PF04570.9 KEP64247.1 - 0.084 12.1 0.2 0.084 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF581) Rad1 PF02144.11 KEP64248.1 - 0.021 13.5 0.0 0.099 11.3 0.0 1.8 2 0 0 2 2 2 0 Repair protein Rad1/Rec1/Rad17 Glyco_hydro_31 PF01055.21 KEP64249.1 - 2.9e-139 464.6 0.2 3.9e-139 464.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEP64249.1 - 4.1e-11 42.5 0.0 1.4e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like SBF2 PF12335.3 KEP64249.1 - 0.2 10.9 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 Myotubularin protein Actin PF00022.14 KEP64250.1 - 8.2e-81 271.4 0.0 9.4e-74 248.1 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KEP64250.1 - 3.5e-05 22.5 0.0 0.064 11.8 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein Ebp2 PF05890.7 KEP64250.1 - 5.5 6.2 12.1 10 5.3 8.4 1.4 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 WD40 PF00400.27 KEP64251.1 - 2.6e-17 61.9 10.5 7.1e-07 28.8 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat TatD_DNase PF01026.16 KEP64252.1 - 3.7e-44 150.8 0.0 4.4e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase tRNA_anti-codon PF01336.20 KEP64253.1 - 0.00044 20.0 0.0 0.0068 16.2 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DEAD PF00270.24 KEP64254.1 - 1.2e-40 138.7 0.0 2.1e-39 134.7 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP64254.1 - 2.3e-25 88.2 0.1 4.8e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP64254.1 - 1.1e-08 35.1 0.0 2.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KEP64254.1 - 1.8e-06 27.0 0.0 3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 KEP64254.1 - 0.0064 16.4 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_22 PF13401.1 KEP64254.1 - 0.0073 16.4 0.0 0.023 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP64254.1 - 0.035 13.8 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain T4SS-DNA_transf PF02534.9 KEP64254.1 - 0.064 11.8 0.0 0.14 10.6 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer UvrD-helicase PF00580.16 KEP64254.1 - 0.068 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KEP64254.1 - 0.1 11.7 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Kinesin PF00225.18 KEP64256.1 - 8.9e-115 382.9 1.0 1.1e-114 382.6 0.7 1.1 1 0 0 1 1 1 1 Kinesin motor domain ResIII PF04851.10 KEP64256.1 - 0.014 15.2 0.7 0.057 13.2 0.1 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Asp PF00026.18 KEP64257.1 - 0.029 13.6 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic aspartyl protease GMC_oxred_C PF05199.8 KEP64258.1 - 1.8e-16 60.7 0.0 1.5e-11 44.7 0.0 2.7 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.14 KEP64258.1 - 5.6e-15 55.2 0.0 2.1e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 KEP64258.1 - 3.6e-05 22.8 0.1 8e-05 21.7 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 KEP64258.1 - 0.001 18.5 0.1 0.0024 17.3 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KEP64258.1 - 0.0019 18.5 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEP64258.1 - 0.0046 15.8 0.3 0.0081 15.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEP64258.1 - 0.0076 16.2 0.1 0.023 14.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEP64258.1 - 0.0096 14.8 0.1 0.018 13.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEP64258.1 - 0.014 15.3 0.1 0.045 13.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEP64258.1 - 0.019 13.8 0.4 0.034 13.0 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 KEP64258.1 - 0.035 12.5 0.1 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 KEP64258.1 - 0.067 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 ThiF family GDI PF00996.13 KEP64258.1 - 0.077 11.2 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor TrkA_N PF02254.13 KEP64258.1 - 0.13 12.2 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 KEP64258.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Bac_Ubq_Cox PF01654.12 KEP64259.1 - 0.011 14.1 0.0 0.019 13.3 0.0 1.3 1 1 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase MFS_1 PF07690.11 KEP64260.1 - 1.9e-07 30.1 20.0 2.3e-07 29.8 13.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KEP64260.1 - 0.0052 15.2 6.5 0.0078 14.6 4.5 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein GMC_oxred_C PF05199.8 KEP64262.1 - 4.2e-17 62.7 0.0 1.2e-12 48.2 0.0 2.8 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_N PF00732.14 KEP64262.1 - 2.8e-13 49.6 0.0 5.5e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 KEP64262.1 - 0.0018 17.2 0.2 0.0033 16.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEP64262.1 - 0.014 15.4 0.3 0.037 14.0 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEP64262.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KEP64262.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 KEP64262.1 - 0.17 11.6 0.2 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 ThiF family TPR_19 PF14559.1 KEP64263.1 - 0.1 12.9 0.1 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M14 PF00246.19 KEP64264.1 - 6.1e-26 91.6 0.0 1.6e-25 90.2 0.0 1.6 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 KEP64264.1 - 0.0046 15.8 0.0 0.0082 15.0 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family tRNA-synt_1 PF00133.17 KEP64267.1 - 4.1e-182 606.3 0.0 3.8e-181 603.1 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEP64267.1 - 4.3e-37 127.2 0.0 1.1e-36 125.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEP64267.1 - 2.2e-15 56.2 0.1 2.5e-06 26.3 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KEP64267.1 - 5e-09 35.7 0.5 1.4e-07 30.9 0.0 2.7 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KEP64267.1 - 2.2e-05 24.4 7.9 5.4e-05 23.1 5.4 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 KEP64267.1 - 0.00036 19.4 0.1 0.015 14.1 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 KEP64267.1 - 0.021 13.9 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.16 KEP64267.1 - 0.025 13.2 0.1 0.47 9.0 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1e PF01406.14 KEP64267.1 - 0.028 13.5 0.0 0.29 10.1 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GCV_H PF01597.14 KEP64269.1 - 0.00021 20.9 0.0 0.0005 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein Pkinase PF00069.20 KEP64271.1 - 9.1e-07 28.2 0.0 5.4e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEP64271.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KEP64271.1 - 0.052 12.6 0.0 0.17 10.9 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase DUF4200 PF13863.1 KEP64272.1 - 2e-25 89.1 27.4 2e-25 89.1 19.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) USP8_interact PF08941.5 KEP64272.1 - 0.021 14.1 2.0 0.063 12.5 1.4 1.9 1 0 0 1 1 1 0 USP8 interacting DUF3675 PF12428.3 KEP64273.1 - 0.02 15.1 1.7 0.044 14.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Syntaxin-6_N PF09177.6 KEP64273.1 - 0.022 15.1 1.2 0.022 15.1 0.8 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Amnionless PF14828.1 KEP64273.1 - 0.077 11.4 0.3 0.12 10.8 0.2 1.3 1 0 0 1 1 1 0 Amnionless DUF4064 PF13273.1 KEP64273.1 - 0.098 12.7 0.3 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) LdpA_C PF12617.3 KEP64273.1 - 0.12 11.6 1.1 1.4 8.1 0.1 2.7 3 0 0 3 3 3 0 Iron-Sulfur binding protein C terminal CheZ PF04344.8 KEP64273.1 - 0.21 11.2 5.7 0.12 12.0 0.4 2.3 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ Laminin_II PF06009.7 KEP64273.1 - 0.43 10.3 8.1 0.53 10.0 1.5 2.6 2 1 1 3 3 3 0 Laminin Domain II SNARE PF05739.14 KEP64273.1 - 0.5 10.0 11.5 0.025 14.2 2.5 2.7 3 0 0 3 3 3 0 SNARE domain AP2 PF00847.15 KEP64275.1 - 7.5e-10 38.8 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 AP2 domain PRKCSH_1 PF13015.1 KEP64277.1 - 4.3e-10 39.2 0.0 8.5e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.2 KEP64277.1 - 8.4e-10 38.4 17.6 7.8e-06 25.5 0.2 3.8 4 0 0 4 4 4 3 Glucosidase II beta subunit-like DUF972 PF06156.8 KEP64277.1 - 0.08 13.2 0.8 2 8.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Lge1 PF11488.3 KEP64277.1 - 0.089 12.9 0.7 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DivIC PF04977.10 KEP64277.1 - 6.1 6.4 17.0 0.045 13.2 0.7 2.9 3 0 0 3 3 3 0 Septum formation initiator PQ-loop PF04193.9 KEP64279.1 - 3.5e-22 77.7 0.9 2.6e-11 42.8 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KEP64279.1 - 9.4e-05 22.2 2.5 0.015 15.1 0.1 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF1422 PF07226.6 KEP64279.1 - 0.066 12.9 3.5 0.14 11.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) Ureidogly_hydro PF04115.7 KEP64279.1 - 0.091 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Ureidoglycolate hydrolase Asn_synthase PF00733.16 KEP64280.1 - 2e-74 250.2 0.0 2.7e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KEP64280.1 - 2.7e-32 111.1 0.0 4.7e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KEP64280.1 - 1.8e-19 70.0 0.0 1.1e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KEP64280.1 - 1.1e-08 34.5 0.1 2.7e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KEP64280.1 - 6.1e-07 28.4 0.0 0.053 12.2 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KEP64280.1 - 0.0011 17.8 0.0 0.0025 16.7 0.0 1.6 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 KEP64280.1 - 0.013 14.0 0.0 0.023 13.2 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase WD40 PF00400.27 KEP64281.1 - 4.9e-19 67.4 6.9 6.4e-05 22.6 0.0 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase PF00069.20 KEP64282.1 - 2.6e-32 112.0 0.0 5.8e-17 61.7 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64282.1 - 1e-09 37.8 0.0 0.0071 15.4 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Cornifin PF02389.10 KEP64283.1 - 0.0095 15.7 2.3 0.016 14.9 1.2 1.6 1 1 0 1 1 1 1 Cornifin (SPRR) family Fer4_10 PF13237.1 KEP64283.1 - 0.042 13.6 0.2 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain IMCp PF12314.3 KEP64284.1 - 5.4e-22 77.7 119.9 1.2e-13 51.0 13.3 7.0 1 1 5 6 6 6 4 Inner membrane complex protein TP6A_N PF04406.9 KEP64285.1 - 1.3e-12 47.1 0.3 2.8e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 KEP64285.1 - 1.7e-08 34.4 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) DUF2220 PF09983.4 KEP64285.1 - 1.3e-05 24.4 0.0 2.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) His_Phos_2 PF00328.17 KEP64286.1 - 0.00099 18.5 0.0 3.6 6.8 0.0 3.1 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) IFT57 PF10498.4 KEP64288.1 - 3.7e-17 62.1 1.2 1.2e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 DUF677 PF05055.7 KEP64288.1 - 0.18 10.4 1.9 0.28 9.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) TPT PF03151.11 KEP64290.1 - 6.5e-09 35.6 19.4 2.4e-06 27.2 8.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KEP64290.1 - 1.3e-06 27.6 0.9 3.2e-06 26.4 0.6 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KEP64290.1 - 5.6e-06 26.4 2.8 5.6e-06 26.4 1.9 3.2 1 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 KEP64290.1 - 2e-05 24.7 4.5 2e-05 24.7 3.1 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 KEP64290.1 - 0.0069 16.1 0.1 0.0069 16.1 0.1 2.5 2 1 0 2 2 2 1 Uncharacterised protein family UPF0546 UAA PF08449.6 KEP64290.1 - 0.044 12.6 14.0 0.078 11.8 9.7 1.3 1 1 0 1 1 1 0 UAA transporter family Multi_Drug_Res PF00893.14 KEP64290.1 - 0.11 13.0 0.2 0.11 13.0 0.2 3.8 3 1 1 4 4 4 0 Small Multidrug Resistance protein DUF4181 PF13789.1 KEP64290.1 - 0.34 10.8 5.8 0.086 12.7 0.5 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4181) DUF4199 PF13858.1 KEP64290.1 - 0.49 10.2 5.5 15 5.4 1.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF1129 PF06570.6 KEP64290.1 - 0.73 9.1 4.0 1.1 8.4 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) U3_assoc_6 PF08640.6 KEP64291.1 - 3.5e-15 55.5 0.9 3.5e-15 55.5 0.6 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 RNase_P_Rpp14 PF01900.14 KEP64292.1 - 9.5e-14 51.2 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family WD40 PF00400.27 KEP64294.1 - 1.2e-10 40.8 3.8 5.9e-06 25.9 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4111 PF13427.1 KEP64296.1 - 1.2 8.9 6.7 0.22 11.3 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) Pkinase PF00069.20 KEP64297.1 - 1.5e-35 122.6 0.0 1.3e-11 44.1 0.0 4.4 4 1 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64297.1 - 9.1e-07 28.1 0.0 0.0038 16.3 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KEP64297.1 - 0.0082 15.8 0.2 0.021 14.5 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEP64297.1 - 0.49 9.4 1.6 1.1 8.2 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NRDE-2 PF08424.5 KEP64299.1 - 0.0042 16.0 0.0 0.008 15.1 0.0 1.4 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference Ion_trans PF00520.26 KEP64300.1 - 8.4e-05 21.9 2.3 8.4e-05 21.9 1.6 1.8 2 0 0 2 2 2 1 Ion transport protein CTDII PF01556.13 KEP64301.1 - 5.6e-20 71.0 2.8 2e-13 50.0 0.2 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEP64301.1 - 2.7e-11 43.3 20.4 2.7e-11 43.3 14.2 2.1 2 0 0 2 2 2 1 DnaJ central domain DnaJ PF00226.26 KEP64301.1 - 0.0012 18.4 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3545 PF12065.3 KEP64302.1 - 0.0032 17.1 3.1 0.0033 17.1 1.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3545) Mitofilin PF09731.4 KEP64302.1 - 0.0067 15.1 1.6 0.008 14.8 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Kinesin-relat_1 PF12711.2 KEP64302.1 - 0.01 16.1 3.0 0.014 15.7 0.5 2.0 2 0 0 2 2 2 0 Kinesin motor GAS PF13851.1 KEP64302.1 - 0.011 14.8 0.6 0.011 14.8 0.4 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KEP64302.1 - 0.038 13.5 4.8 0.05 13.1 3.3 1.3 1 1 0 1 1 1 0 IncA protein DUF1465 PF07323.7 KEP64302.1 - 0.077 12.5 0.9 0.1 12.1 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Spc24 PF08286.6 KEP64302.1 - 0.25 11.0 2.0 0.86 9.3 0.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.10 KEP64302.1 - 0.28 11.0 0.2 0.28 11.0 0.1 2.6 3 0 0 3 3 3 0 Basic region leucine zipper KLRAQ PF10205.4 KEP64302.1 - 0.31 11.0 3.7 0.47 10.5 0.6 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF972 PF06156.8 KEP64302.1 - 0.33 11.2 5.1 0.25 11.7 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 KEP64302.1 - 0.41 11.0 3.3 15 6.0 0.2 2.7 2 1 0 2 2 2 0 SlyX Prp19 PF08606.6 KEP64302.1 - 0.46 10.2 4.9 0.72 9.6 0.1 2.4 2 1 0 2 2 2 0 Prp19/Pso4-like DUF904 PF06005.7 KEP64302.1 - 0.53 10.6 4.6 0.75 10.1 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ADIP PF11559.3 KEP64302.1 - 0.61 9.9 5.5 0.14 12.0 1.4 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KEP64302.1 - 1.9 7.3 9.5 1.3 7.9 5.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 KEP64302.1 - 4.7 6.9 9.0 1.3 8.7 3.1 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MFS_1 PF07690.11 KEP64306.1 - 5.3e-22 78.0 61.1 7.6e-19 67.6 10.2 2.5 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KEP64306.1 - 4.6e-15 55.1 37.1 1e-14 53.9 4.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 KEP64306.1 - 0.068 11.2 27.3 0.13 10.2 4.5 4.2 4 1 1 5 5 5 0 Organic Anion Transporter Polypeptide (OATP) family DUF3394 PF11874.3 KEP64306.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) DAGK_cat PF00781.19 KEP64307.1 - 6e-05 22.4 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Cse1 PF08506.5 KEP64308.1 - 4e-84 282.3 0.0 1.8e-83 280.1 0.0 2.1 2 1 1 3 3 3 1 Cse1 CAS_CSE1 PF03378.10 KEP64308.1 - 3.9e-62 209.9 5.4 7.3e-62 209.0 3.7 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 KEP64308.1 - 3.6e-08 33.2 0.1 2.2e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KEP64308.1 - 0.027 14.3 6.2 0.37 10.6 0.0 4.3 4 1 0 4 4 4 0 Exportin 1-like protein TPR_11 PF13414.1 KEP64310.1 - 0.29 10.7 13.1 1.1 9.0 0.4 3.7 4 0 0 4 4 4 0 TPR repeat PLU-1 PF08429.6 KEP64311.1 - 5.1e-28 97.9 49.7 2.7e-15 56.0 0.1 8.4 6 2 0 6 6 6 5 PLU-1-like protein PHD PF00628.24 KEP64311.1 - 0.091 12.4 0.0 0.49 10.1 0.0 2.3 1 0 0 1 1 1 0 PHD-finger GTP_cyclohydroI PF01227.17 KEP64315.1 - 3e-72 241.6 0.0 4.2e-72 241.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KEP64315.1 - 0.00075 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein zf-CCCH PF00642.19 KEP64316.1 - 2.8e-14 52.4 16.5 4.6e-07 29.3 3.5 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Wound_ind PF08186.6 KEP64316.1 - 0.051 13.4 0.7 0.62 10.0 0.1 2.6 2 0 0 2 2 2 0 Wound-inducible basic protein family Ribosomal_L18e PF00828.14 KEP64317.1 - 0.0026 18.1 0.8 0.066 13.5 0.0 2.6 1 1 1 2 2 2 1 Ribosomal protein L18e/L15 FHA PF00498.21 KEP64318.1 - 8.1e-05 22.6 0.0 0.49 10.5 0.0 2.6 2 0 0 2 2 2 2 FHA domain LLC1 PF14945.1 KEP64318.1 - 0.064 13.5 1.3 0.17 12.2 0.9 1.7 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein GAS PF13851.1 KEP64318.1 - 0.081 12.1 19.4 0.14 11.3 13.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KEP64318.1 - 0.4 10.2 32.4 2.3 7.7 22.3 2.1 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 KEP64318.1 - 1.2 8.0 21.7 2.4 7.0 15.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PHF5 PF03660.9 KEP64321.1 - 0.26 11.3 7.8 1.2 9.1 1.0 2.4 2 0 0 2 2 2 0 PHF5-like protein Pkinase PF00069.20 KEP64322.1 - 1.4e-39 135.8 0.0 1.3e-36 126.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64322.1 - 1.6e-38 132.3 0.0 3.4e-37 127.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEP64322.1 - 0.012 15.3 5.8 0.091 12.4 1.0 3.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEP64322.1 - 0.061 12.3 0.1 0.44 9.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_2 PF07647.12 KEP64322.1 - 0.27 11.1 0.0 0.49 10.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ELO PF01151.13 KEP64325.1 - 2.8e-49 167.6 21.3 5.5e-49 166.7 14.8 1.4 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_M16_C PF05193.16 KEP64326.1 - 3e-27 95.4 0.0 8.6e-13 48.3 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEP64326.1 - 2.4e-12 46.8 0.2 6.7e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) ALAD PF00490.16 KEP64327.1 - 1.3e-138 461.3 0.1 1.6e-138 461.0 0.1 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase YL1 PF05764.8 KEP64327.1 - 0.082 12.5 6.6 0.16 11.5 4.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 KEP64327.1 - 0.63 7.8 7.7 0.92 7.3 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KEP64327.1 - 1.5 6.7 6.7 2.2 6.2 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.3 KEP64327.1 - 5.2 6.9 19.2 11 5.8 13.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GCC2_GCC3 PF07699.8 KEP64329.1 - 3.8e-18 64.8 431.5 8.7e-05 22.0 2.6 43.2 36 9 4 41 41 41 25 GCC2 and GCC3 ACT_4 PF13291.1 KEP64329.1 - 1 9.7 0.0 3.5 8.0 0.0 1.9 1 0 0 1 1 1 0 ACT domain DUF2975 PF11188.3 KEP64329.1 - 2.8 7.6 0.0 5 6.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Pkinase PF00069.20 KEP64330.1 - 1.3e-68 230.9 0.0 1.9e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64330.1 - 4.1e-32 111.2 0.0 5.5e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP64330.1 - 1.4e-08 34.0 0.0 3.7e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 KEP64330.1 - 0.0052 16.5 0.3 0.049 13.3 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEP64330.1 - 0.0097 14.9 0.0 0.0097 14.9 0.0 2.2 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family XAP5 PF04921.9 KEP64331.1 - 2.1e-78 263.1 7.9 2.1e-78 263.1 5.5 2.6 1 1 1 2 2 2 1 XAP5, circadian clock regulator adh_short PF00106.20 KEP64332.1 - 4e-11 43.1 1.6 5.5e-06 26.4 0.2 2.4 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 KEP64332.1 - 0.0023 17.6 0.3 2.8 7.5 0.2 2.7 2 1 1 3 3 3 2 KR domain Pol_alpha_B_N PF08418.5 KEP64333.1 - 0.22 11.0 10.5 0.047 13.2 5.2 1.5 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Hex_IIIa PF02455.11 KEP64333.1 - 0.28 9.8 5.9 0.32 9.6 4.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) ER-remodelling PF14755.1 KEP64333.1 - 2.8 8.0 14.7 1.1 9.3 0.8 2.6 1 1 1 2 2 2 0 Intracellular membrane remodeller Herpes_UL32 PF06070.6 KEP64333.1 - 3.1 6.1 14.6 3.3 6.0 10.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 HTH_32 PF13565.1 KEP64336.1 - 1.4 9.7 0.0 1.4 9.7 0.0 3.6 3 0 0 3 3 3 0 Homeodomain-like domain Peptidase_S28 PF05577.7 KEP64337.1 - 5.5e-69 232.8 0.1 1e-68 231.9 0.0 1.4 2 0 0 2 2 2 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 KEP64337.1 - 1.2e-07 31.8 5.4 1.3e-06 28.4 3.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP64337.1 - 0.0047 16.6 0.2 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 KEP64338.1 - 3.3e-11 42.6 9.9 0.0052 16.6 0.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat YgbB PF02542.11 KEP64338.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 YgbB family zf-CDGSH PF09360.5 KEP64339.1 - 5.9e-22 77.2 10.6 2.7e-14 52.7 2.6 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type DUF4475 PF14753.1 KEP64339.1 - 0.46 9.9 6.2 0.26 10.7 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4475) Metallothio_Euk PF12749.2 KEP64339.1 - 0.93 9.5 5.5 11 6.1 0.6 2.2 2 0 0 2 2 2 0 Eukaryotic metallothionein OPA3 PF07047.7 KEP64341.1 - 1.4e-33 115.5 0.9 1.8e-33 115.1 0.6 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SAG PF04092.8 KEP64342.1 - 1.5e-18 67.4 6.4 7.9e-10 39.1 1.9 2.2 2 0 0 2 2 2 2 SRS domain SIP PF04954.8 KEP64342.1 - 0.14 12.4 0.1 1.3 9.3 0.0 2.5 2 2 0 2 2 2 0 Siderophore-interacting protein DUF4064 PF13273.1 KEP64343.1 - 3.6 7.7 9.9 8.4 6.5 3.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Zip PF02535.17 KEP64344.1 - 1.3e-19 70.4 3.8 2.3e-19 69.5 2.6 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter HemY_N PF07219.8 KEP64344.1 - 0.19 11.3 1.8 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 HemY protein N-terminus Cyt-b5 PF00173.23 KEP64345.1 - 5.6e-06 26.0 0.0 9.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain tRNA-synt_1b PF00579.20 KEP64346.1 - 4e-29 101.6 0.0 3.6e-19 68.9 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) Atg8 PF02991.11 KEP64347.1 - 1.8e-34 117.8 0.4 4.5e-34 116.5 0.3 1.6 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KEP64347.1 - 5.6e-05 23.2 0.2 0.00022 21.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RAP PF08373.5 KEP64348.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 RAP domain DNA_RNApol_7kD PF03604.8 KEP64349.1 - 1.2e-14 53.3 6.4 2.1e-14 52.6 4.4 1.4 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 KEP64349.1 - 0.024 14.4 1.3 0.05 13.4 0.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 KEP64349.1 - 0.033 13.8 1.2 0.05 13.2 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GFA PF04828.9 KEP64349.1 - 0.039 13.8 2.0 3 7.8 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-dskA_traR PF01258.12 KEP64349.1 - 0.21 11.3 4.3 0.39 10.5 3.0 1.4 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zf-ISL3 PF14690.1 KEP64349.1 - 0.4 10.7 0.2 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.2 KEP64349.1 - 6.9 6.5 6.8 2 8.3 0.2 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Radial_spoke_3 PF06098.6 KEP64353.1 - 1.4e-56 191.6 6.8 1.4e-56 191.6 4.7 2.5 2 1 1 3 3 3 1 Radial spoke protein 3 Pkinase PF00069.20 KEP64354.1 - 3.3e-68 229.6 0.0 3.7e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64354.1 - 9.7e-40 136.2 0.0 1.1e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP64354.1 - 3.3e-13 49.2 0.0 6.8e-13 48.2 0.0 1.4 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KEP64354.1 - 3.5e-09 36.0 0.3 8.1e-09 34.8 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP64354.1 - 7.2e-08 32.4 0.0 3.5e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KEP64354.1 - 4e-07 29.5 0.6 5.4e-06 25.8 0.5 1.9 1 1 1 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KEP64354.1 - 0.0027 17.3 0.1 0.0059 16.1 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase tRNA-synt_2b PF00587.20 KEP64355.1 - 3.8e-25 88.4 0.0 6.4e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEP64355.1 - 1.5e-21 76.1 0.0 2.5e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain CSTF2_hinge PF14327.1 KEP64357.1 - 5.1e-07 29.6 0.2 1.2e-06 28.4 0.2 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KEP64357.1 - 0.00039 19.9 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64357.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP64358.1 - 4.2e-05 23.0 0.0 7.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64358.1 - 0.00014 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64358.1 - 0.23 11.3 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TatD_DNase PF01026.16 KEP64359.1 - 0.049 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase PRELI PF04707.9 KEP64360.1 - 1.7e-30 105.6 0.0 2.4e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family UPF0203 PF05254.7 KEP64361.1 - 0.082 12.7 0.7 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Ribosomal_60s PF00428.14 KEP64361.1 - 0.32 11.4 5.8 0.14 12.5 1.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein MRFAP1 PF15155.1 KEP64361.1 - 2.1 8.6 5.5 22 5.3 0.2 2.3 2 0 0 2 2 2 0 MORF4 family-associated protein1 TRAM_LAG1_CLN8 PF03798.11 KEP64362.1 - 1.5e-20 73.6 14.7 1.5e-20 73.6 10.2 1.6 2 0 0 2 2 2 1 TLC domain RNA_pol_Rpb4 PF03874.11 KEP64363.1 - 6.6e-10 39.0 0.0 1.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb4 Bul1_N PF04425.7 KEP64365.1 - 0.84 8.1 0.0 1.6 7.2 0.0 1.3 1 0 0 1 1 1 0 Bul1 N terminus Lipase_3 PF01764.20 KEP64368.1 - 3.2e-08 33.2 0.0 8.9e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) SAYSvFN PF10260.4 KEP64369.1 - 1.6e-11 43.8 0.1 2.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.10 KEP64369.1 - 3.4e-07 29.6 9.6 5.2e-07 29.0 6.6 1.3 1 0 0 1 1 1 1 SEC-C motif Glyco_hydro_81 PF03639.8 KEP64370.1 - 1.2e-17 63.2 0.8 2.4e-17 62.2 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 Kelch_4 PF13418.1 KEP64371.1 - 0.0025 17.5 0.1 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 Galactose oxidase, central domain YfzA PF14118.1 KEP64372.1 - 0.047 13.8 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 YfzA-like protein Kinase-like PF14531.1 KEP64373.1 - 2.8e-13 49.4 0.0 6.2e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.20 KEP64373.1 - 0.042 12.9 0.0 0.11 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein kinase domain CTP_transf_1 PF01148.15 KEP64374.1 - 1.1e-06 28.4 4.2 0.00014 21.5 0.2 2.3 1 1 1 2 2 2 2 Cytidylyltransferase family DUF1230 PF06799.6 KEP64374.1 - 0.12 12.1 0.3 0.31 10.9 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1230) DUF454 PF04304.8 KEP64374.1 - 0.13 12.2 0.2 0.13 12.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF454) DUF202 PF02656.10 KEP64374.1 - 0.18 12.0 3.7 0.27 11.4 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Guanylate_cyc PF00211.15 KEP64375.1 - 1e-76 256.4 0.1 2.8e-41 140.9 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HAD PF12710.2 KEP64375.1 - 2.5e-16 60.4 0.0 3e-11 43.8 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEP64375.1 - 6.1e-15 56.2 0.0 1.8e-11 44.8 0.0 3.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEP64375.1 - 1.4e-14 53.7 0.0 2.9e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KEP64375.1 - 2.8e-05 23.9 0.0 7.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEP64375.1 - 7.5e-05 22.4 0.0 0.00042 19.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L11_N PF03946.9 KEP64376.1 - 3.6e-20 71.1 0.0 5.3e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KEP64376.1 - 4.4e-17 61.9 0.0 6.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NOC3p PF07540.6 KEP64376.1 - 0.029 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Nucleolar complex-associated protein CRAL_TRIO PF00650.15 KEP64377.1 - 3.6e-23 81.7 0.1 5e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KEP64377.1 - 1.3e-05 25.1 0.1 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ax_dynein_light PF10211.4 KEP64377.1 - 0.12 12.2 4.3 0.31 10.8 3.0 1.7 1 0 0 1 1 1 0 Axonemal dynein light chain Ycf1 PF05758.7 KEP64377.1 - 0.53 7.9 3.6 0.76 7.4 2.5 1.2 1 0 0 1 1 1 0 Ycf1 Ribosomal_L2_C PF03947.13 KEP64378.1 - 7.4e-49 164.8 0.4 1.2e-48 164.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KEP64378.1 - 1.9e-23 82.1 0.0 3.1e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SpoIIE PF07228.7 KEP64379.1 - 2.7e-12 46.8 0.2 1.2e-11 44.7 0.2 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEP64379.1 - 1.7e-08 34.1 0.0 1.4e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KEP64379.1 - 0.00013 21.4 0.0 0.018 14.4 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Patatin PF01734.17 KEP64380.1 - 1.6e-06 28.2 1.1 9.9e-06 25.6 0.0 2.5 2 0 0 2 2 2 1 Patatin-like phospholipase PAN_4 PF14295.1 KEP64381.1 - 1.1e-47 159.5 44.7 1.3e-09 37.6 1.5 7.6 7 0 0 7 7 7 7 PAN domain PAN_1 PF00024.21 KEP64381.1 - 5.2e-47 157.4 51.8 5.9e-09 35.5 0.4 7.2 6 1 1 7 7 7 7 PAN domain PAN_2 PF08276.6 KEP64381.1 - 0.00035 20.3 41.9 1.1 9.2 0.4 7.3 7 0 0 7 7 7 6 PAN-like domain PAN_3 PF08277.7 KEP64381.1 - 7.6 6.2 41.0 0.055 13.0 1.1 6.4 7 0 0 7 7 7 0 PAN-like domain Ribosomal_L11_N PF03946.9 KEP64382.1 - 8e-17 60.4 0.1 1.2e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KEP64382.1 - 1.2e-12 47.7 0.0 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain eRF1_1 PF03463.10 KEP64383.1 - 8.8e-39 132.1 0.1 1.3e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 KEP64383.1 - 1.1e-20 74.2 0.0 1.8e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KEP64383.1 - 9.6e-17 61.2 0.0 2.3e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 DUF2326 PF10088.4 KEP64383.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2326) XPA_C PF05181.7 KEP64384.1 - 6.3e-05 22.4 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 XPA protein C-terminus WD40 PF00400.27 KEP64386.1 - 0.00015 21.5 0.6 0.0045 16.8 0.1 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Sel1 PF08238.7 KEP64387.1 - 2.3e-20 72.5 24.0 0.016 15.8 0.0 11.6 12 0 0 12 12 12 7 Sel1 repeat TPR_11 PF13414.1 KEP64387.1 - 0.042 13.4 5.9 13 5.4 0.1 4.1 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 KEP64387.1 - 0.23 11.1 1.9 11 5.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 KEP64388.1 - 1e-08 34.7 1.2 0.0063 16.3 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Macoilin PF09726.4 KEP64388.1 - 0.36 9.0 14.8 0.49 8.6 10.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_16 PF10294.4 KEP64389.1 - 1.1e-18 67.2 0.0 3.6e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Ank PF00023.25 KEP64389.1 - 1.7e-08 33.8 0.2 3.8e-06 26.4 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 KEP64389.1 - 2.5e-08 34.1 0.2 1.2e-07 32.0 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEP64389.1 - 1.3e-06 28.0 0.1 0.001 19.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 KEP64389.1 - 0.00013 22.3 0.0 0.032 14.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEP64389.1 - 0.00038 20.6 0.0 0.0059 16.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_18 PF12847.2 KEP64389.1 - 0.0029 18.1 0.1 0.008 16.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP64389.1 - 0.0095 15.6 0.0 0.032 13.9 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEP64389.1 - 0.0099 15.2 0.1 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Prefoldin_2 PF01920.15 KEP64391.1 - 1.6e-08 34.2 5.7 3.2e-08 33.2 3.9 1.6 1 1 0 1 1 1 1 Prefoldin subunit WXG100 PF06013.7 KEP64391.1 - 0.0042 17.0 7.8 0.12 12.3 1.7 2.4 2 0 0 2 2 2 2 Proteins of 100 residues with WXG YlqD PF11068.3 KEP64391.1 - 0.0046 17.0 9.4 0.075 13.0 1.2 2.1 2 0 0 2 2 2 2 YlqD protein Cast PF10174.4 KEP64391.1 - 0.02 12.9 9.3 0.023 12.7 6.5 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Baculo_PEP_C PF04513.7 KEP64391.1 - 0.053 13.3 4.7 2.3 8.0 3.3 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Striatin PF08232.7 KEP64391.1 - 0.059 13.6 5.8 0.078 13.2 0.7 2.1 2 0 0 2 2 2 0 Striatin family Snapin_Pallidin PF14712.1 KEP64391.1 - 0.073 13.3 8.3 0.13 12.5 0.2 2.7 2 1 1 3 3 3 0 Snapin/Pallidin bZIP_1 PF00170.16 KEP64391.1 - 0.096 12.6 4.3 0.14 12.1 1.3 2.1 2 0 0 2 2 2 0 bZIP transcription factor EIAV_Rev PF11129.3 KEP64391.1 - 0.11 12.4 0.3 0.18 11.8 0.1 1.4 1 1 0 1 1 1 0 Rev protein of equine infectious anaemia virus Tropomyosin_1 PF12718.2 KEP64391.1 - 0.11 12.2 6.6 0.19 11.5 4.6 1.3 1 1 0 1 1 1 0 Tropomyosin like SseC PF04888.7 KEP64391.1 - 0.17 11.1 11.8 0.2 10.9 8.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family UPF0184 PF03670.8 KEP64391.1 - 0.18 12.0 1.0 17 5.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Uds1 PF15456.1 KEP64391.1 - 0.2 11.6 5.8 0.24 11.3 4.0 1.2 1 0 0 1 1 1 0 Up-regulated During Septation CENP-Q PF13094.1 KEP64391.1 - 0.21 11.5 7.1 2.9 7.9 1.1 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Snf7 PF03357.16 KEP64391.1 - 0.22 10.9 10.9 0.12 11.6 1.1 2.2 2 0 0 2 2 2 0 Snf7 Bacillus_HBL PF05791.6 KEP64391.1 - 0.27 10.5 8.2 0.46 9.8 1.1 2.1 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2175 PF09943.4 KEP64391.1 - 0.28 11.2 2.0 0.67 10.0 0.2 2.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) DUF1664 PF07889.7 KEP64391.1 - 0.31 10.8 3.6 10 5.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RRF_GI PF12614.3 KEP64391.1 - 0.42 10.4 5.3 2.3 8.0 3.7 1.9 1 1 0 1 1 1 0 Ribosome recycling factor TBPIP PF07106.8 KEP64391.1 - 0.46 10.0 5.6 3.9 6.9 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NTR2 PF15458.1 KEP64391.1 - 0.83 8.8 11.1 0.22 10.7 2.3 2.1 1 1 1 2 2 2 0 Nineteen complex-related protein 2 FliJ PF02050.11 KEP64391.1 - 1.2 9.1 13.8 1.9 8.5 3.4 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein Remorin_C PF03763.8 KEP64391.1 - 1.5 8.3 6.6 0.56 9.7 1.0 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region Seryl_tRNA_N PF02403.17 KEP64391.1 - 1.6 8.7 8.6 1.6 8.7 0.3 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4404 PF14357.1 KEP64391.1 - 2 8.9 8.7 0.98 9.8 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) GAS PF13851.1 KEP64391.1 - 2.1 7.4 9.2 0.79 8.8 1.9 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KEP64391.1 - 3.4 7.4 11.9 3.9 7.2 3.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3585 PF12130.3 KEP64391.1 - 4 7.2 9.6 17 5.2 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3585) HrpB7 PF09486.5 KEP64391.1 - 4.4 7.2 15.4 1.2 9.0 2.3 2.3 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ADIP PF11559.3 KEP64391.1 - 4.6 7.1 9.6 6.2 6.7 2.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Viral_P18 PF04521.8 KEP64391.1 - 4.8 6.6 8.7 9.7 5.6 0.1 2.7 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein V_ATPase_I PF01496.14 KEP64391.1 - 5.1 4.8 7.7 4.9 4.8 0.5 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.6 KEP64391.1 - 5.7 5.4 9.1 18 3.8 6.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.8 KEP64391.1 - 5.8 6.7 7.8 2 8.2 0.7 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF148 PF02520.12 KEP64391.1 - 9.6 6.0 9.5 2 8.2 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 MRP-L28 PF09812.4 KEP64392.1 - 0.074 12.8 2.4 0.16 11.7 1.7 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 CDP-OH_P_transf PF01066.16 KEP64394.1 - 2e-10 40.8 0.2 5.5e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Macoilin PF09726.4 KEP64394.1 - 0.0093 14.2 0.2 0.015 13.6 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein ELL PF10390.4 KEP64394.1 - 0.03 13.5 5.5 0.053 12.7 3.8 1.3 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Sporozoite_P67 PF05642.6 KEP64394.1 - 0.39 8.5 6.1 0.8 7.4 4.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Borrelia_P83 PF05262.6 KEP64394.1 - 2.2 6.4 6.5 3.2 5.9 4.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Bromodomain PF00439.20 KEP64395.1 - 1.5e-23 82.5 0.1 2.9e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KEP64395.1 - 2.5e-11 43.5 1.2 5.9e-11 42.3 0.9 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEP64395.1 - 1.3e-10 41.1 0.2 3.4e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEP64395.1 - 0.00015 21.8 0.0 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP64395.1 - 0.0049 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KEP64395.1 - 0.0095 15.7 0.1 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEP64395.1 - 0.072 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UAA PF08449.6 KEP64397.1 - 2.7e-69 233.4 22.4 3.3e-69 233.1 15.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEP64397.1 - 3.4e-08 33.5 29.5 9.3e-08 32.1 4.6 3.3 2 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 KEP64397.1 - 1e-05 25.2 5.1 1e-05 25.2 3.6 3.0 2 1 0 3 3 3 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KEP64397.1 - 0.002 17.2 0.5 0.087 11.9 0.0 2.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF202 PF02656.10 KEP64397.1 - 0.17 12.0 9.1 2.7 8.2 0.1 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF202) DUF1980 PF09323.5 KEP64397.1 - 0.41 10.3 4.8 0.3 10.8 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) ubiquitin PF00240.18 KEP64399.1 - 2.2e-23 81.4 0.5 2.4e-23 81.2 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEP64399.1 - 2.5e-13 49.4 0.3 2.8e-13 49.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEP64399.1 - 1.5e-05 25.1 0.1 4.7e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KEP64399.1 - 0.00071 19.4 0.1 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEP64399.1 - 0.013 15.6 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SPRR2 PF14820.1 KEP64400.1 - 0.54 10.1 13.6 0.047 13.5 6.0 1.7 2 0 0 2 2 2 0 Small proline-rich 2 zf-Tim10_DDP PF02953.10 KEP64401.1 - 9.2e-13 47.2 3.2 1.3e-12 46.8 2.2 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KEP64401.1 - 0.046 13.1 2.1 0.077 12.4 1.4 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TACI-CRD2 PF09305.5 KEP64401.1 - 0.47 10.2 2.3 0.36 10.6 0.4 1.7 2 0 0 2 2 2 0 TACI, cysteine-rich domain Ribosomal_L39 PF00832.15 KEP64402.1 - 4.5e-21 74.0 9.8 5.2e-21 73.8 6.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Pkinase PF00069.20 KEP64404.1 - 1.8e-29 102.7 0.0 1.6e-17 63.5 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64404.1 - 2e-11 43.4 0.3 6e-09 35.3 0.0 3.5 4 0 0 4 4 4 1 Protein tyrosine kinase APH PF01636.18 KEP64404.1 - 0.043 13.5 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP64404.1 - 0.077 11.9 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like DNA_pol_delta_4 PF04081.8 KEP64406.1 - 1.6e-15 57.5 0.0 2.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 RRM_1 PF00076.17 KEP64407.1 - 8.5e-13 47.7 0.0 1.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64407.1 - 1.7e-09 37.4 0.0 3.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64407.1 - 1.5e-06 27.9 0.0 3.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KEP64407.1 - 1.7e-06 27.5 0.7 3.7e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 KEP64407.1 - 0.00088 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEP64407.1 - 0.002 17.9 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif zf-CCCH_2 PF14608.1 KEP64407.1 - 0.17 11.9 1.3 0.46 10.5 0.9 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type FYVE PF01363.16 KEP64407.1 - 0.3 11.0 4.6 0.15 11.9 1.4 2.0 2 1 0 2 2 2 0 FYVE zinc finger Ank_2 PF12796.2 KEP64408.1 - 1.6e-18 66.8 0.1 1.1e-14 54.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP64408.1 - 3.3e-12 46.5 2.2 3.9e-09 36.7 0.2 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEP64408.1 - 1.2e-11 44.4 0.9 8.3e-07 29.0 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP64408.1 - 6.9e-11 41.2 2.5 0.00016 21.5 0.0 4.5 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.25 KEP64408.1 - 9.4e-10 37.8 6.5 0.00035 20.2 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat DUF1129 PF06570.6 KEP64409.1 - 0.0047 16.2 0.4 0.0074 15.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Abhydrolase_5 PF12695.2 KEP64411.1 - 6.2e-26 90.8 0.0 3e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP64411.1 - 4.4e-20 72.5 1.5 2.9e-18 66.5 0.0 3.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEP64411.1 - 1.4e-09 37.6 0.0 1.2e-05 24.8 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KEP64411.1 - 1.2e-07 31.5 0.0 0.0037 16.8 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KEP64411.1 - 1.6e-06 27.8 0.4 3.7e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 KEP64411.1 - 8.1e-06 24.5 0.1 0.054 11.9 0.0 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KEP64411.1 - 1.5e-05 24.3 0.0 3.6e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2305 PF10230.4 KEP64411.1 - 0.00056 19.4 0.0 0.1 11.9 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2305) BAAT_C PF08840.6 KEP64411.1 - 0.0084 15.8 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 KEP64411.1 - 0.011 15.1 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 KEP64411.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 KEP64411.1 - 0.014 14.7 0.0 0.19 10.9 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF818 PF05677.7 KEP64411.1 - 0.091 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF676 PF05057.9 KEP64413.1 - 9.2e-42 142.8 0.0 1.4e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 KEP64413.1 - 0.00013 21.9 0.0 0.00038 20.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3657) PGAP1 PF07819.8 KEP64413.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KEP64413.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Menin PF05053.8 KEP64413.1 - 8.1 4.4 6.2 14 3.6 4.3 1.3 1 0 0 1 1 1 0 Menin POP1 PF06978.6 KEP64415.1 - 1.6e-31 109.4 16.4 1.6e-31 109.4 11.3 4.3 2 1 1 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KEP64415.1 - 4.7e-16 58.4 0.9 2.1e-15 56.3 0.0 2.6 3 0 0 3 3 3 1 POPLD (NUC188) domain GCV_T_C PF08669.6 KEP64415.1 - 0.06 13.3 0.0 0.25 11.4 0.0 2.1 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Ribonuc_L-PSP PF01042.16 KEP64416.1 - 2.8e-13 49.7 0.0 3.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP HNH_2 PF13391.1 KEP64416.1 - 0.13 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 HNH endonuclease PaaSYMP PF14738.1 KEP64417.1 - 2.9e-18 66.0 17.2 2.9e-18 66.0 11.9 3.1 3 1 1 4 4 4 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 DUF1759 PF03564.10 KEP64417.1 - 0.43 10.3 5.8 0.11 12.3 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) ThiS PF02597.15 KEP64417.1 - 0.84 10.0 5.3 1.2 9.5 0.2 3.2 3 0 0 3 3 3 0 ThiS family DUF4392 PF14336.1 KEP64418.1 - 1.6e-70 237.2 0.0 1.9e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) AIRS PF00586.19 KEP64418.1 - 0.12 12.5 0.0 0.43 10.8 0.0 1.9 2 1 0 2 2 2 0 AIR synthase related protein, N-terminal domain Metallophos PF00149.23 KEP64419.1 - 4.5e-09 35.9 0.2 7.8e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 KEP64419.1 - 0.0064 14.5 0.2 0.34 8.8 0.0 2.1 2 0 0 2 2 2 2 Firmicute fructose-1,6-bisphosphatase Hepar_II_III PF07940.8 KEP64419.1 - 0.019 14.8 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 Heparinase II/III-like protein Metallophos_2 PF12850.2 KEP64419.1 - 0.033 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GvpL_GvpF PF06386.6 KEP64420.1 - 0.019 14.5 0.1 0.024 14.2 0.1 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Complex1_LYR_1 PF13232.1 KEP64422.1 - 0.0028 17.8 0.7 0.0054 16.8 0.4 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEP64422.1 - 0.011 15.5 0.2 0.021 14.6 0.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF4240 PF14024.1 KEP64422.1 - 0.019 14.7 0.1 0.027 14.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4240) Glutaredoxin2_C PF04399.8 KEP64422.1 - 0.11 12.1 0.2 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain FAST_1 PF06743.10 KEP64423.1 - 0.065 12.9 0.1 0.23 11.1 0.0 2.0 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Methyltransf_16 PF10294.4 KEP64425.1 - 0.051 13.0 0.1 16 4.8 0.0 3.1 3 0 0 3 3 3 0 Putative methyltransferase RRM_1 PF00076.17 KEP64426.1 - 0.00049 19.6 0.0 0.0009 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64426.1 - 0.00065 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 KEP64426.1 - 0.0016 17.0 17.4 0.0016 17.0 12.1 2.7 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 RRM_5 PF13893.1 KEP64426.1 - 0.015 15.1 0.1 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.1 KEP64427.1 - 1.7e-12 47.0 20.2 6.9e-06 25.9 5.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP64427.1 - 1.2e-11 43.5 19.6 0.0028 17.4 0.2 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 KEP64427.1 - 1.4e-09 37.1 11.4 0.00057 19.3 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEP64427.1 - 5.7e-09 35.5 17.3 2.3e-08 33.5 2.8 3.3 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 KEP64427.1 - 1.7e-06 27.4 3.3 0.011 15.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEP64427.1 - 5.1e-06 26.5 4.0 0.03 14.7 0.3 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEP64427.1 - 2.8e-05 23.5 16.0 0.11 12.4 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEP64427.1 - 3.2e-05 23.7 19.4 0.034 14.0 0.2 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEP64427.1 - 0.0017 18.9 22.4 0.24 12.1 2.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEP64427.1 - 0.002 18.6 16.8 1.3 9.8 0.3 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEP64427.1 - 0.068 13.6 0.5 0.068 13.6 0.4 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 KEP64428.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2968 PF11180.3 KEP64428.1 - 0.019 14.3 5.4 0.029 13.7 2.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) DASH_Spc34 PF08657.5 KEP64428.1 - 0.028 14.0 1.0 0.028 14.0 0.7 2.8 2 1 1 3 3 3 0 DASH complex subunit Spc34 Syntaxin PF00804.20 KEP64428.1 - 0.064 13.4 6.6 11 6.2 4.6 3.0 1 1 0 1 1 1 0 Syntaxin DUF1664 PF07889.7 KEP64428.1 - 0.13 12.0 2.4 1.6 8.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 KEP64428.1 - 0.22 9.3 3.0 0.35 8.6 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.6 KEP64428.1 - 0.28 10.4 2.2 1.5 8.0 0.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein SlyX PF04102.7 KEP64428.1 - 0.32 11.3 2.8 0.82 10.0 0.4 2.8 2 0 0 2 2 2 0 SlyX TBPIP PF07106.8 KEP64428.1 - 0.41 10.1 7.5 0.86 9.1 4.8 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Snapin_Pallidin PF14712.1 KEP64428.1 - 0.5 10.7 6.0 11 6.4 0.0 3.3 2 1 2 4 4 4 0 Snapin/Pallidin DUF4200 PF13863.1 KEP64428.1 - 2.4 8.1 13.8 5.3 7.0 9.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 KEP64428.1 - 2.8 8.3 8.4 4.8 7.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF4315 PF14193.1 KEP64428.1 - 8.3 6.4 8.5 11 6.0 0.7 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) AAA_23 PF13476.1 KEP64428.1 - 9 6.5 10.2 17 5.6 7.1 1.6 1 1 0 1 1 1 0 AAA domain Folliculin PF11704.3 KEP64429.1 - 0.069 12.7 0.3 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport TerD PF02342.13 KEP64431.1 - 2.3e-14 53.1 0.0 3.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 TerD domain Melibiase PF02065.13 KEP64432.1 - 6e-09 35.0 0.0 1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Melibiase LLC1 PF14945.1 KEP64432.1 - 0.15 12.3 3.1 0.33 11.2 0.0 2.6 2 1 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein CRAL_TRIO PF00650.15 KEP64433.1 - 5.1e-11 42.3 0.0 7.1e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Proteasome PF00227.21 KEP64434.1 - 5e-37 127.0 0.0 5.6e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin_C PF02984.14 KEP64435.1 - 0.01 15.7 0.1 0.058 13.3 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_N PF00134.18 KEP64435.1 - 0.11 12.0 0.8 19 4.8 0.1 3.0 3 0 0 3 3 3 0 Cyclin, N-terminal domain Adeno_E3_15_3 PF03307.9 KEP64436.1 - 0.14 11.8 0.5 0.28 10.9 0.4 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region MIF4G PF02854.14 KEP64439.1 - 9.6e-29 100.2 3.3 1.3e-28 99.8 2.3 1.2 1 0 0 1 1 1 1 MIF4G domain DUF1093 PF06486.6 KEP64439.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1093) MA3 PF02847.12 KEP64439.1 - 1.4 8.6 0.1 6.7 6.4 0.0 1.9 2 0 0 2 2 2 0 MA3 domain DUF3102 PF11300.3 KEP64439.1 - 1.5 8.8 0.1 2.6 8.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Bac_GDH PF05088.7 KEP64439.1 - 1.8 5.8 0.5 3.1 5.0 0.3 1.2 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase V_ATPase_I PF01496.14 KEP64439.1 - 6.7 4.4 0.7 10 3.8 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Methyltransf_15 PF09445.5 KEP64440.1 - 6.1e-24 84.4 0.0 2e-23 82.7 0.0 1.8 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.1 KEP64440.1 - 0.018 15.3 0.5 0.041 14.2 0.4 1.6 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 KEP64446.1 - 3.2e-08 33.1 0.5 1.1e-07 31.4 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEP64446.1 - 2.2e-06 27.1 0.3 5e-06 26.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KEP64446.1 - 0.0031 17.0 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain CTP_synth_N PF06418.9 KEP64448.1 - 6e-119 396.1 0.1 8.3e-119 395.7 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KEP64448.1 - 6.9e-46 156.1 0.0 1.1e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEP64448.1 - 3e-07 30.0 0.0 6.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KEP64448.1 - 2.4e-05 23.8 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KEP64448.1 - 0.0025 16.6 0.9 0.0042 15.9 0.6 1.3 1 0 0 1 1 1 1 ArgK protein Acetyltransf_5 PF13444.1 KEP64448.1 - 0.014 15.9 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TRAPP PF04051.11 KEP64449.1 - 2.8e-32 111.3 0.0 3.3e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-B_box PF00643.19 KEP64450.1 - 2e-09 37.1 19.3 4.3e-07 29.7 3.8 4.3 4 1 0 4 4 4 2 B-box zinc finger Synaptobrevin PF00957.16 KEP64451.1 - 8.7e-09 34.8 1.7 1.3e-08 34.3 1.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEP64451.1 - 4.5e-08 32.5 0.0 9.3e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain FAA_hydrolase_N PF09298.6 KEP64451.1 - 1.1 9.3 5.4 0.096 12.6 0.7 1.6 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal Ten1_2 PF15490.1 KEP64452.1 - 2.5e-07 30.2 0.1 2.4e-05 23.9 0.2 2.5 2 1 0 2 2 2 2 Telomere-capping, CST complex subunit AAA PF00004.24 KEP64453.1 - 1.8e-32 112.2 0.0 1.2e-31 109.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP64453.1 - 4.2e-05 23.6 5.7 0.0016 18.4 0.1 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KEP64453.1 - 0.0007 20.4 0.0 0.002 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEP64453.1 - 0.00091 18.0 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 KEP64453.1 - 0.0012 18.9 0.0 0.099 12.7 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEP64453.1 - 0.0027 17.4 1.1 0.011 15.4 0.6 2.2 1 1 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KEP64453.1 - 0.0098 14.9 0.0 0.026 13.5 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KEP64453.1 - 0.015 14.9 0.2 0.076 12.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEP64453.1 - 0.02 14.3 0.2 0.039 13.3 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 KEP64453.1 - 0.023 14.5 0.5 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KEP64453.1 - 0.042 13.3 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Pex14_N PF04695.8 KEP64453.1 - 0.053 13.5 7.0 0.13 12.3 4.8 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PhoH PF02562.11 KEP64453.1 - 0.13 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein AP2 PF00847.15 KEP64455.1 - 4.6e-12 45.9 4.4 1.4e-06 28.3 0.3 2.6 2 0 0 2 2 2 2 AP2 domain Spore_III_AB PF09548.5 KEP64456.1 - 0.075 12.7 1.4 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CLPTM1 PF05602.7 KEP64458.1 - 6.5e-29 100.9 1.9 8.2e-28 97.2 1.3 2.1 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) LrgA PF03788.9 KEP64458.1 - 0.002 17.7 0.1 0.0062 16.2 0.1 1.8 1 0 0 1 1 1 1 LrgA family PQ-loop PF04193.9 KEP64458.1 - 0.018 14.5 0.8 0.13 11.8 0.2 2.5 2 0 0 2 2 2 0 PQ loop repeat VTC PF09359.5 KEP64460.1 - 1.1e-133 444.5 0.0 2.2e-133 443.6 0.0 1.5 1 1 0 1 1 1 1 VTC domain DUF202 PF02656.10 KEP64460.1 - 9e-08 32.2 0.6 2.9e-07 30.6 0.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.14 KEP64460.1 - 0.00018 21.3 0.2 0.00018 21.3 0.1 2.4 2 0 0 2 2 2 1 SPX domain PK PF00224.16 KEP64461.1 - 2.6e-91 305.8 0.5 3.8e-47 160.6 1.2 3.1 2 1 0 3 3 3 3 Pyruvate kinase, barrel domain PK_C PF02887.11 KEP64461.1 - 8.7e-19 67.2 0.0 3.4e-17 62.0 0.0 2.6 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KEP64461.1 - 5.9e-06 25.3 0.2 0.00012 21.0 0.0 2.8 3 0 0 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family DUF4631 PF15450.1 KEP64462.1 - 0.017 13.4 7.5 0.021 13.1 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) DUF4111 PF13427.1 KEP64462.1 - 0.041 13.7 0.7 0.059 13.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) TPR_MLP1_2 PF07926.7 KEP64462.1 - 0.47 10.1 7.3 0.61 9.8 5.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.4 KEP64462.1 - 0.8 9.6 4.5 0.95 9.4 3.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein APG6 PF04111.7 KEP64462.1 - 4.2 6.3 7.9 5.3 5.9 5.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KEP64462.1 - 4.4 6.8 10.1 20 4.7 7.0 1.9 1 1 0 1 1 1 0 IncA protein Na_H_Exchanger PF00999.16 KEP64463.1 - 4.3e-45 153.8 40.7 6.9e-45 153.2 28.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_L22 PF00237.14 KEP64464.1 - 3.5e-30 104.0 0.3 5.5e-30 103.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L18p PF00861.17 KEP64464.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal L18p/L5e family GPI2 PF06432.6 KEP64465.1 - 1.7e-80 270.3 13.8 2e-80 270.1 9.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1440 PF07274.7 KEP64465.1 - 0.018 14.9 1.5 0.034 14.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1440) PspB PF06667.7 KEP64465.1 - 0.094 12.6 0.4 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Phage shock protein B RRM_2 PF04059.7 KEP64466.1 - 5.3e-32 109.6 0.3 7.6e-32 109.1 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 AP2 PF00847.15 KEP64467.1 - 4.3e-09 36.3 1.0 8.7e-09 35.4 0.7 1.6 1 0 0 1 1 1 1 AP2 domain ACDC PF14733.1 KEP64467.1 - 3.1e-07 30.4 0.0 7e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 AP2-coincident C-terminal NDUF_B4 PF07225.7 KEP64467.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Suf PF05843.9 KEP64468.1 - 0.84 9.3 4.4 0.96 9.1 3.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NADH-u_ox-rdase PF10785.4 KEP64469.1 - 0.077 13.2 0.0 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NAD_binding_1 PF00175.16 KEP64470.1 - 1.2e-19 70.8 0.0 2.1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEP64470.1 - 4.3e-05 23.5 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEP64470.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PseudoU_synth_2 PF00849.17 KEP64471.1 - 2.9e-23 82.5 3.7 1.7e-12 47.5 0.0 3.2 2 1 0 2 2 2 2 RNA pseudouridylate synthase PGBA_C PF15437.1 KEP64471.1 - 0.012 15.7 9.7 0.032 14.3 6.7 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DUF3043 PF11241.3 KEP64471.1 - 0.79 9.2 6.9 1.8 8.1 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) LSM PF01423.17 KEP64472.1 - 8.8e-19 66.8 0.0 1.1e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain HSP90 PF00183.13 KEP64473.1 - 2.2e-69 234.2 0.4 7e-68 229.3 0.1 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 KEP64473.1 - 9.7e-12 44.7 0.1 1.9e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEP64473.1 - 1.1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BRE1 PF08647.6 KEP64474.1 - 0.0021 17.9 13.6 0.0021 17.9 9.4 9.8 4 3 5 10 10 10 1 BRE1 E3 ubiquitin ligase DUF4611 PF15387.1 KEP64474.1 - 0.006 16.6 1.0 0.006 16.6 0.7 5.6 6 3 2 8 8 8 1 Domain of unknown function (DUF4611) BLOC1_2 PF10046.4 KEP64474.1 - 0.015 15.4 2.5 0.015 15.4 1.8 9.1 5 2 4 11 11 11 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 KEP64475.1 - 4.3 6.3 21.7 2.8 6.9 6.4 2.4 2 0 0 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KEP64475.1 - 7.7 4.2 1.3 15 3.3 0.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PDEase_I PF00233.14 KEP64479.1 - 8.1e-49 166.5 7.5 1.5e-27 96.8 1.9 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase GAF_3 PF13492.1 KEP64479.1 - 3.3e-08 33.6 0.0 1.9e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 GAF domain Sybindin PF04099.7 KEP64483.1 - 6.8e-44 149.0 0.0 7.7e-44 148.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KEP64483.1 - 1.2e-08 34.8 0.0 1.3e-08 34.7 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region SPRY PF00622.23 KEP64484.1 - 4.3e-14 52.6 0.0 7.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 KEP64484.1 - 1.6e-12 47.3 0.0 3.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain HEAT PF02985.17 KEP64484.1 - 0.0069 16.3 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 HEAT repeat ELFV_dehydrog PF00208.16 KEP64486.1 - 1.1e-85 287.0 0.2 1.5e-85 286.6 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KEP64486.1 - 3.4e-47 159.2 0.0 6.3e-47 158.4 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KEP64486.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Exo_endo_phos PF03372.18 KEP64487.1 - 2.4e-16 60.4 0.0 3.7e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MMgT PF10270.4 KEP64488.1 - 1.8e-09 37.9 0.0 2.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter DUF1206 PF06724.6 KEP64488.1 - 0.12 12.1 0.6 0.12 12.1 0.4 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) zf-DHHC PF01529.15 KEP64489.1 - 1.8e-34 118.6 11.7 1.3e-33 115.8 8.7 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1426 PF07234.6 KEP64489.1 - 0.2 11.4 1.9 0.68 9.6 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) DUF2465 PF10239.4 KEP64490.1 - 9.1e-65 218.9 0.0 1.2e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Abhydro_lipase PF04083.11 KEP64491.1 - 2.3e-09 36.4 0.0 7.6e-05 21.9 0.0 2.5 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KEP64491.1 - 0.0012 18.4 0.2 0.017 14.6 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEP64491.1 - 0.0024 17.6 0.0 0.66 9.7 0.0 2.9 2 1 0 2 2 2 2 Alpha/beta hydrolase family HATPase_c PF02518.21 KEP64495.1 - 4.6e-10 39.2 0.1 2.4e-08 33.6 0.0 2.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cyclin PF08613.6 KEP64496.1 - 3.9e-24 85.7 0.3 1.4e-23 83.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin WW PF00397.21 KEP64498.1 - 7.4e-09 35.3 6.1 2e-08 33.9 4.2 1.8 1 0 0 1 1 1 1 WW domain Yip1 PF04893.12 KEP64498.1 - 4.6e-05 22.9 17.1 0.00078 18.9 12.1 2.1 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.10 KEP64498.1 - 0.018 14.2 0.0 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 YIF1 Ribosomal_L20 PF00453.13 KEP64499.1 - 1.4e-30 105.3 1.1 1.6e-30 105.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 DUF179 PF02622.10 KEP64501.1 - 3.1e-10 39.8 0.0 5.2e-08 32.6 0.0 3.0 3 0 0 3 3 3 2 Uncharacterized ACR, COG1678 Ran_BP1 PF00638.13 KEP64502.1 - 2.7e-39 134.0 1.1 2.7e-39 134.0 0.8 1.8 1 1 1 2 2 2 1 RanBP1 domain WH1 PF00568.18 KEP64502.1 - 0.12 12.1 1.4 0.34 10.6 0.9 1.8 1 1 0 1 1 1 0 WH1 domain AhpC-TSA PF00578.16 KEP64502.1 - 0.12 12.0 0.8 0.22 11.1 0.5 1.4 1 0 0 1 1 1 0 AhpC/TSA family Mito_carr PF00153.22 KEP64503.1 - 2e-50 168.4 3.7 1.4e-16 59.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Met_10 PF02475.11 KEP64505.1 - 2.5e-06 27.2 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KEP64505.1 - 4.3e-05 24.0 0.1 0.00015 22.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEP64505.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KEP64505.1 - 0.0081 16.1 0.0 0.027 14.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP64505.1 - 0.081 12.6 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEP64505.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Hat1_N PF10394.4 KEP64506.1 - 2.1e-32 112.4 8.5 7.5e-32 110.6 5.9 1.8 1 1 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Ycf1 PF05758.7 KEP64506.1 - 0.069 10.8 11.7 0.093 10.4 8.1 1.2 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 KEP64506.1 - 0.82 7.2 5.4 1.2 6.7 3.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.4 KEP64506.1 - 5.9 6.2 49.1 0.01 15.2 2.0 3.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Cyto_heme_lyase PF01265.12 KEP64507.1 - 5.8e-62 209.6 1.1 5.8e-62 209.6 0.7 1.8 2 0 0 2 2 2 1 Cytochrome c/c1 heme lyase DUF3592 PF12158.3 KEP64509.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) MFS_1 PF07690.11 KEP64510.1 - 2.3e-13 49.6 18.9 2.3e-13 49.6 13.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily CedA PF10729.4 KEP64510.1 - 0.15 11.6 0.1 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Cell division activator CedA MFS_1 PF07690.11 KEP64511.1 - 0.029 13.1 11.5 0.041 12.5 8.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Polysacc_synt_C PF14667.1 KEP64511.1 - 0.7 9.6 10.9 1.1 9.0 7.6 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Sre PF03125.13 KEP64511.1 - 2.8 6.7 6.7 0.54 9.1 2.4 1.4 1 1 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor TctA PF01970.11 KEP64512.1 - 0.0032 15.9 3.1 0.0032 15.9 2.1 1.6 3 0 0 3 3 3 1 Tripartite tricarboxylate transporter TctA family Ni_hydr_CYTB PF01292.15 KEP64512.1 - 0.11 11.8 1.7 0.33 10.3 0.5 2.2 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 RDD PF06271.7 KEP64512.1 - 0.47 10.3 13.5 2 8.3 5.5 2.7 2 1 1 3 3 3 0 RDD family PP2C PF00481.16 KEP64514.1 - 1.2e-44 152.7 0.0 1.4e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEP64514.1 - 6.2e-08 32.5 0.1 0.00071 19.3 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KEP64514.1 - 1.5e-05 24.5 0.0 7.5e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C DNA_ligase_A_N PF04675.9 KEP64515.1 - 3.8e-29 101.7 0.0 3.6e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEP64515.1 - 2.3e-15 56.7 0.0 7.5e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.16 KEP64515.1 - 8.6e-15 54.6 0.0 1.9e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain BRCT PF00533.21 KEP64515.1 - 0.00029 20.9 0.0 0.0016 18.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEP64515.1 - 0.002 17.9 0.0 0.0053 16.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain STAT2_C PF12188.3 KEP64516.1 - 0.046 13.5 0.8 0.099 12.4 0.2 1.8 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal MoCF_biosynth PF00994.19 KEP64517.1 - 2e-25 88.8 0.0 1.5e-09 37.4 0.0 5.9 4 2 1 5 5 5 4 Probable molybdopterin binding domain MoeA_N PF03453.12 KEP64517.1 - 1.3e-23 83.1 0.2 6.4e-15 54.8 0.1 2.5 2 0 0 2 2 2 2 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KEP64517.1 - 0.00039 20.3 0.0 0.049 13.5 0.0 2.6 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Gram_pos_anchor PF00746.16 KEP64518.1 - 0.78 9.6 0.0 0.78 9.6 0.0 2.6 2 0 0 2 2 2 0 Gram positive anchor DUF1213 PF06740.7 KEP64518.1 - 2 8.6 11.1 7.2 6.8 3.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) zf-PARP PF00645.13 KEP64520.1 - 9.4e-14 51.4 1.3 3.9e-13 49.4 0.9 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.7 KEP64520.1 - 4.4e-10 38.7 5.1 4.8e-10 38.6 0.1 2.3 2 0 0 2 2 2 1 PADR1 (NUC008) domain SAP PF02037.22 KEP64520.1 - 1.5e-06 27.5 0.1 3.1e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain TF_Zn_Ribbon PF08271.7 KEP64520.1 - 0.025 13.8 1.3 0.025 13.8 0.9 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding Sec62 PF03839.11 KEP64524.1 - 8.7e-26 90.7 5.5 1.4e-25 90.0 3.8 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.4 KEP64524.1 - 0.83 8.1 3.1 1.2 7.6 2.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Prefoldin_2 PF01920.15 KEP64525.1 - 9.1e-18 63.9 2.0 1.3e-17 63.5 1.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit BicD PF09730.4 KEP64525.1 - 0.03 12.6 4.1 0.045 12.1 2.9 1.5 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D GAS PF13851.1 KEP64525.1 - 0.059 12.5 2.5 0.97 8.5 0.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Resolvase PF00239.16 KEP64525.1 - 0.1 12.4 0.4 0.26 11.1 0.2 1.6 1 1 0 1 1 1 0 Resolvase, N terminal domain vATP-synt_E PF01991.13 KEP64525.1 - 0.25 10.5 2.6 1.2 8.3 0.1 2.2 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit DASH_Spc19 PF08287.6 KEP64525.1 - 0.65 9.5 4.1 0.44 10.1 0.2 2.0 1 1 1 2 2 2 0 Spc19 Cep57_CLD PF14073.1 KEP64525.1 - 0.86 9.3 6.6 5.4 6.8 4.3 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 TMF_TATA_bd PF12325.3 KEP64525.1 - 1 9.1 5.7 14 5.4 3.9 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Ribosomal_60s PF00428.14 KEP64525.1 - 6.2 7.3 12.4 0.11 12.8 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein ketoacyl-synt PF00109.21 KEP64526.1 - 8.9e-55 185.9 0.4 1.4e-54 185.2 0.3 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEP64526.1 - 5e-38 129.6 0.2 9.8e-38 128.6 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KEP64526.1 - 0.04 12.9 0.4 0.076 11.9 0.3 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ribosomal_L27 PF01016.14 KEP64527.1 - 3e-28 97.4 0.1 6.4e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein Amidohydro_2 PF04909.9 KEP64528.1 - 2e-07 30.8 0.0 4e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KEP64528.1 - 0.0016 18.5 4.0 0.012 15.6 2.7 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEP64528.1 - 0.04 13.5 0.2 0.089 12.4 0.1 1.7 1 1 0 1 1 1 0 Amidohydrolase family DUF72 PF01904.13 KEP64528.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF72 DUF826 PF05696.6 KEP64529.1 - 0.25 11.4 4.9 0.1 12.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF826) DUF3546 PF12066.3 KEP64530.1 - 5.6e-15 55.2 2.8 1.1e-14 54.3 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 KEP64530.1 - 2.2e-05 24.7 1.1 3.7e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 KEP64530.1 - 7.3e-05 22.2 0.1 0.00023 20.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) IcmL PF11393.3 KEP64530.1 - 0.03 14.2 0.2 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein zf-C2H2 PF00096.21 KEP64530.1 - 0.1 12.9 3.4 0.24 11.8 2.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type VacJ PF04333.8 KEP64532.1 - 0.046 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 VacJ like lipoprotein TFIIS_M PF07500.9 KEP64533.1 - 2.6e-28 98.3 0.3 4.3e-28 97.6 0.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KEP64533.1 - 1.7e-18 65.9 5.9 4.6e-18 64.5 4.1 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KEP64533.1 - 1.2e-14 53.4 0.0 2.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CENP-P PF13096.1 KEP64533.1 - 0.12 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Profilin PF00235.14 KEP64535.1 - 3e-13 49.9 0.6 5e-13 49.2 0.4 1.3 1 1 0 1 1 1 1 Profilin WD40 PF00400.27 KEP64536.1 - 5.7e-12 45.0 15.7 0.0025 17.6 0.1 6.9 6 1 0 6 6 6 4 WD domain, G-beta repeat zf-RanBP PF00641.13 KEP64537.1 - 1e-06 27.7 21.7 0.001 18.1 5.9 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 KEP64537.1 - 0.0047 16.7 12.7 0.37 10.6 0.9 2.6 2 0 0 2 2 2 2 Double zinc ribbon FUR PF01475.14 KEP64537.1 - 1.7 8.5 4.4 3.2 7.7 0.1 2.3 1 1 1 2 2 2 0 Ferric uptake regulator family DUF35_N PF12172.3 KEP64537.1 - 2.3 8.2 16.9 7.3 6.6 2.0 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HAD_2 PF13419.1 KEP64538.1 - 0.00011 22.4 0.4 0.045 13.9 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase zf-DHHC PF01529.15 KEP64539.1 - 1.3e-25 89.8 12.8 2.8e-25 88.7 8.9 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.2 KEP64539.1 - 1.3e-22 79.9 0.2 5.5e-11 42.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP64539.1 - 1.5e-21 76.3 0.7 1.4e-07 31.8 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KEP64539.1 - 4.8e-18 63.9 1.0 2e-08 33.6 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KEP64539.1 - 2.6e-15 55.0 3.1 0.00064 19.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KEP64539.1 - 4.5e-13 48.9 4.0 1.8e-06 28.0 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) EF-hand_7 PF13499.1 KEP64541.1 - 4.1e-16 58.8 6.4 5.4e-08 32.8 0.0 4.3 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP64541.1 - 2.2e-14 51.5 12.5 0.0076 15.4 0.0 6.3 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.1 KEP64541.1 - 2.7e-12 45.4 13.4 0.018 14.8 0.1 6.8 7 0 0 7 7 7 4 EF-hand domain EF-hand_8 PF13833.1 KEP64541.1 - 1.8e-09 37.0 12.1 0.17 11.5 0.0 5.7 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.1 KEP64541.1 - 8.5e-08 31.2 20.1 0.0026 17.0 0.0 6.3 6 0 0 6 6 6 3 EF hand SPARC_Ca_bdg PF10591.4 KEP64541.1 - 0.00067 19.6 0.2 4.4 7.3 0.0 3.5 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Excalibur PF05901.6 KEP64541.1 - 1.7 9.0 4.0 44 4.5 0.1 3.8 3 0 0 3 3 3 0 Excalibur calcium-binding domain Glyco_hydro_19 PF00182.14 KEP64542.1 - 1e-13 51.5 0.1 7.5e-13 48.6 0.1 2.3 1 1 0 1 1 1 1 Chitinase class I SAS4 PF15460.1 KEP64544.1 - 1.3 8.9 5.5 1.4 8.8 0.1 2.8 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 DUF2453 PF10507.4 KEP64545.1 - 6.8e-35 119.2 2.2 8.9e-35 118.8 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) DUF1072 PF06380.6 KEP64545.1 - 0.14 11.8 0.3 0.14 11.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) PepSY_TM_2 PF13703.1 KEP64545.1 - 0.64 10.2 3.2 0.23 11.6 0.4 1.7 2 0 0 2 2 2 0 PepSY-associated TM helix PEP_mutase PF13714.1 KEP64546.1 - 1.1e-53 181.9 0.1 1.3e-53 181.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KEP64546.1 - 4.2e-19 68.1 0.2 7.1e-19 67.3 0.1 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Peptidase_C2 PF00648.16 KEP64547.1 - 3.2e-35 121.5 0.1 1.4e-27 96.4 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.17 KEP64547.1 - 1.6e-12 47.2 0.2 4.2e-09 36.2 0.0 3.2 3 1 0 3 3 3 2 Calpain large subunit, domain III Methyltransf_PK PF05891.7 KEP64548.1 - 3e-09 36.4 0.0 1.1e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.1 KEP64548.1 - 1.1e-08 35.3 0.0 3.3e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP64548.1 - 1.7e-08 34.8 0.1 3.6e-06 27.3 0.0 3.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP64548.1 - 5.6e-08 33.3 0.0 2e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP64548.1 - 8.8e-08 32.0 0.0 5.5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 KEP64548.1 - 8.1e-06 25.0 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 KEP64548.1 - 1.4e-05 25.5 0.0 3.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP64548.1 - 0.00054 19.5 0.0 0.0061 16.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP64548.1 - 0.00057 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 KEP64548.1 - 0.0096 15.3 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.13 KEP64548.1 - 0.026 13.7 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase PIN_2 PF10130.4 KEP64548.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 PIN domain Cluap1 PF10234.4 KEP64551.1 - 5.8e-29 101.1 8.3 5.8e-29 101.1 5.8 2.7 1 1 1 2 2 2 1 Clusterin-associated protein-1 CS PF04969.11 KEP64552.1 - 2.2e-06 28.1 0.0 3.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 CS domain Thioredoxin PF00085.15 KEP64553.1 - 3.4e-29 100.5 0.6 3.8e-29 100.4 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEP64553.1 - 2.9e-06 27.2 0.1 6.4e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEP64553.1 - 4.7e-06 26.7 0.2 4e-05 23.7 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KEP64553.1 - 1.5e-05 24.5 0.1 1.6e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KEP64553.1 - 0.0001 21.9 0.1 0.00012 21.8 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KEP64553.1 - 0.0002 21.2 0.1 0.00031 20.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KEP64553.1 - 0.02 14.4 0.1 0.033 13.7 0.1 1.4 1 1 0 1 1 1 0 Redoxin WD40 PF00400.27 KEP64554.1 - 8e-21 73.0 23.1 1.1e-09 37.8 0.2 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.6 KEP64554.1 - 0.00033 20.4 0.0 0.064 12.9 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KEP64554.1 - 0.0085 14.9 0.4 1.3 7.7 0.7 3.2 4 0 0 4 4 4 1 Coatomer WD associated region TSP_1 PF00090.14 KEP64555.1 - 0.045 13.8 2.9 0.2 11.7 2.0 2.2 1 0 0 1 1 1 0 Thrombospondin type 1 domain Tme5_EGF_like PF09064.5 KEP64555.1 - 0.071 12.7 0.6 0.18 11.4 0.4 1.6 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Sua5_yciO_yrdC PF01300.13 KEP64556.1 - 6.6e-34 116.7 0.0 8.1e-33 113.1 0.0 2.4 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 KEP64556.1 - 5.7e-07 29.6 0.0 4e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding SID-1_RNA_chan PF13965.1 KEP64556.1 - 0.1 10.7 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 zf-RING_2 PF13639.1 KEP64558.1 - 1.6e-14 53.4 5.0 2.7e-14 52.7 3.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP64558.1 - 9.4e-09 35.2 1.1 1.9e-08 34.2 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP64558.1 - 2.9e-08 33.2 3.3 4.6e-08 32.5 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP64558.1 - 9.1e-08 32.0 5.7 1.5e-07 31.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP64558.1 - 1.6e-06 27.7 3.4 2.5e-06 27.1 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEP64558.1 - 5.4e-06 25.9 2.4 9.5e-06 25.1 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SOG2 PF10428.4 KEP64558.1 - 0.0027 16.4 3.2 0.0027 16.4 2.2 2.2 2 0 0 2 2 2 1 RAM signalling pathway protein zf-RING_UBOX PF13445.1 KEP64558.1 - 0.0037 16.9 3.2 0.0072 16.0 2.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KEP64558.1 - 0.017 14.9 0.9 0.03 14.1 0.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KEP64558.1 - 0.16 12.0 3.1 0.29 11.1 2.2 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 KEP64558.1 - 0.24 11.3 4.7 0.51 10.2 3.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 KEP64558.1 - 0.3 10.8 2.0 0.58 9.9 1.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Rtf2 PF04641.7 KEP64558.1 - 1.7 7.8 5.2 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger ER_lumen_recept PF00810.13 KEP64559.1 - 9.6e-23 81.3 2.5 9.6e-23 81.3 1.7 2.1 2 0 0 2 2 2 1 ER lumen protein retaining receptor BBE PF08031.7 KEP64559.1 - 0.11 12.4 0.1 22 5.0 0.1 2.4 2 0 0 2 2 2 0 Berberine and berberine like Methyltransf_4 PF02390.12 KEP64562.1 - 6.8e-48 162.3 0.0 8.1e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEP64562.1 - 0.0012 19.3 0.0 0.0024 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP64562.1 - 0.0052 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP64562.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KEP64562.1 - 0.012 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 KEP64562.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEP64562.1 - 0.072 13.5 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 KEP64562.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 KEP64562.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.1 KEP64562.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEP64562.1 - 0.13 12.0 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 KEP64562.1 - 0.16 10.9 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ECH_C PF13766.1 KEP64563.1 - 3.1e-09 36.9 0.3 2.4e-07 30.9 0.1 2.4 2 0 0 2 2 2 2 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KEP64563.1 - 1.1e-08 34.5 0.0 2.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family G6PD_C PF02781.11 KEP64564.1 - 5.1e-88 294.7 0.0 9.8e-87 290.5 0.0 2.0 2 0 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KEP64564.1 - 1.4e-51 175.3 0.0 2.3e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Tropomyosin_1 PF12718.2 KEP64565.1 - 0.01 15.6 22.6 0.01 15.6 15.7 5.9 3 2 2 5 5 5 0 Tropomyosin like bZIP_1 PF00170.16 KEP64565.1 - 1 9.3 0.0 1 9.3 0.0 9.3 5 4 5 10 10 10 0 bZIP transcription factor zf-MYND PF01753.13 KEP64566.1 - 0.0047 16.7 9.0 0.0076 16.1 6.3 1.3 1 0 0 1 1 1 1 MYND finger PDEase_I PF00233.14 KEP64567.1 - 2.5e-52 178.0 0.1 4.3e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KEP64567.1 - 0.15 12.0 0.1 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 HD domain COX2_TM PF02790.10 KEP64568.1 - 7.5e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain WD40 PF00400.27 KEP64570.1 - 4.1e-20 70.8 8.7 6.8e-08 32.0 1.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF2149 PF09919.4 KEP64570.1 - 0.17 11.9 0.3 18 5.5 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2149) Pkinase PF00069.20 KEP64571.1 - 2.2e-49 167.9 0.0 3.3e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64571.1 - 1.3e-35 122.7 0.0 1.8e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP64571.1 - 1e-13 50.9 0.0 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PRMT5 PF05185.11 KEP64572.1 - 1e-18 67.5 0.0 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 KEP64572.1 - 2.4e-08 33.4 0.0 3.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KEP64572.1 - 1e-07 32.5 0.0 3.4e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP64572.1 - 1.5e-06 28.2 0.0 4.6e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP64572.1 - 1.6e-05 24.5 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEP64572.1 - 0.00014 21.3 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 KEP64572.1 - 0.0014 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 KEP64572.1 - 0.0024 17.5 0.0 0.0075 15.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP64572.1 - 0.011 16.1 0.0 0.11 12.9 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 KEP64572.1 - 0.039 13.6 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 KEP64572.1 - 0.065 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 KEP64572.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 KEP64572.1 - 0.098 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEP64572.1 - 0.11 13.0 0.0 0.52 10.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain HECT PF00632.20 KEP64573.1 - 1.4e-80 270.8 0.0 1.9e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DER1 PF04511.10 KEP64574.1 - 5e-40 137.1 7.0 6.2e-40 136.8 4.8 1.0 1 0 0 1 1 1 1 Der1-like family SSF PF00474.12 KEP64576.1 - 2.8e-12 46.0 22.2 2.8e-12 46.0 15.4 1.5 1 1 1 2 2 2 1 Sodium:solute symporter family TPR_16 PF13432.1 KEP64578.1 - 7.7e-18 64.6 20.3 0.00029 21.4 0.5 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEP64578.1 - 1.2e-15 56.9 12.3 1.5e-05 24.5 0.1 5.4 5 1 1 6 6 5 4 TPR repeat Apc3 PF12895.2 KEP64578.1 - 1.7e-11 44.1 16.0 0.005 16.9 0.7 5.6 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEP64578.1 - 2.3e-11 43.4 13.8 7.8e-05 22.5 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEP64578.1 - 3.4e-08 33.7 17.7 0.049 13.9 1.2 6.0 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEP64578.1 - 7.6e-08 32.3 22.8 0.076 13.6 0.5 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEP64578.1 - 1.2e-07 31.3 1.0 0.1 12.8 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEP64578.1 - 2.2e-07 30.2 19.4 0.00014 21.4 0.3 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEP64578.1 - 1.3e-05 24.5 6.5 0.02 14.4 0.5 5.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP64578.1 - 0.00021 20.8 3.1 0.0052 16.4 0.8 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEP64578.1 - 0.00041 20.4 8.1 0.0044 17.1 0.6 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KEP64578.1 - 0.0079 15.4 0.2 0.07 12.3 0.0 2.7 3 0 0 3 3 3 1 SHNi-TPR TPR_6 PF13174.1 KEP64578.1 - 0.097 13.1 5.1 50 4.6 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP64578.1 - 0.4 10.5 3.1 9.2 6.3 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEP64578.1 - 0.41 10.5 9.7 3.4 7.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEP64578.1 - 1.1 9.2 6.9 2.9 7.9 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Histone PF00125.19 KEP64579.1 - 3.4e-19 68.7 0.1 4.6e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEP64579.1 - 0.00028 20.8 0.2 0.00057 19.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KEP64579.1 - 0.00029 21.0 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Na_H_Exchanger PF00999.16 KEP64580.1 - 9.3e-48 162.6 44.9 1.2e-47 162.3 31.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CorA PF01544.13 KEP64581.1 - 3.5e-07 29.5 3.5 2.4e-06 26.7 2.4 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TPR_11 PF13414.1 KEP64582.1 - 1.6e-10 40.4 7.4 0.05 13.2 0.1 6.3 5 1 1 6 6 6 3 TPR repeat TPR_2 PF07719.12 KEP64582.1 - 8.5e-07 28.4 12.0 0.14 12.1 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP64582.1 - 2.1e-06 27.4 2.1 0.061 13.5 0.0 6.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP64582.1 - 2.2e-06 27.7 23.0 0.0016 18.9 0.1 7.6 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEP64582.1 - 6.9e-05 22.7 12.2 0.0026 17.6 0.9 5.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEP64582.1 - 0.00044 19.7 4.0 1.3 8.7 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP64582.1 - 0.0029 17.8 6.8 0.045 14.1 0.1 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP64582.1 - 0.014 16.0 30.0 0.036 14.7 0.1 7.4 6 2 1 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEP64582.1 - 0.034 13.9 0.0 32 4.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP64582.1 - 0.078 12.8 11.0 2.5 8.0 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat DivIC PF04977.10 KEP64583.1 - 3.2e-06 26.5 0.4 5.1e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.16 KEP64583.1 - 4.5e-06 26.5 0.3 7.7e-06 25.7 0.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 KEP64583.1 - 1.8e-05 24.3 1.5 6.3e-05 22.6 1.1 1.9 1 1 0 1 1 1 1 Homeobox associated leucine zipper DUF904 PF06005.7 KEP64583.1 - 3.2e-05 24.1 1.0 3.2e-05 24.1 0.7 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 KEP64583.1 - 4e-05 23.3 0.3 6.6e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TSC22 PF01166.13 KEP64583.1 - 0.00066 19.5 0.6 0.00066 19.5 0.4 1.6 2 0 0 2 2 1 1 TSC-22/dip/bun family bZIP_2 PF07716.10 KEP64583.1 - 0.00067 19.4 0.7 0.0016 18.2 0.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Dapper PF15268.1 KEP64583.1 - 0.0012 17.8 0.7 0.0012 17.8 0.5 1.0 1 0 0 1 1 1 1 Dapper KLRAQ PF10205.4 KEP64583.1 - 0.0012 18.8 0.1 0.002 18.1 0.1 1.4 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Phasin PF05597.6 KEP64583.1 - 0.0012 18.6 0.4 0.12 12.1 0.0 2.3 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) GAS PF13851.1 KEP64583.1 - 0.0024 17.1 0.5 0.0045 16.2 0.0 1.6 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 KEP64583.1 - 0.0028 17.6 0.8 0.0089 16.0 0.2 1.8 2 0 0 2 2 2 1 DivIVA protein FlaC_arch PF05377.6 KEP64583.1 - 0.0031 17.3 1.7 0.01 15.7 0.1 2.1 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) Cortex-I_coil PF09304.5 KEP64583.1 - 0.0038 17.2 0.9 0.0069 16.4 0.6 1.4 1 0 0 1 1 1 1 Cortexillin I, coiled coil DUF2353 PF09789.4 KEP64583.1 - 0.0041 16.4 0.1 0.0048 16.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) GrpE PF01025.14 KEP64583.1 - 0.0049 16.4 0.6 0.08 12.4 0.1 2.0 2 0 0 2 2 2 1 GrpE Filament PF00038.16 KEP64583.1 - 0.0051 16.3 0.1 0.0068 15.9 0.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein LPP PF04728.8 KEP64583.1 - 0.0055 16.4 0.5 0.041 13.6 0.4 2.1 1 1 0 1 1 1 1 Lipoprotein leucine-zipper ADIP PF11559.3 KEP64583.1 - 0.006 16.4 0.3 0.011 15.6 0.2 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF3450 PF11932.3 KEP64583.1 - 0.0063 15.8 0.4 0.01 15.1 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.17 KEP64583.1 - 0.0064 16.4 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 KEP64583.1 - 0.0078 15.1 0.1 0.0078 15.1 0.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Uds1 PF15456.1 KEP64583.1 - 0.0082 16.1 0.6 0.013 15.5 0.4 1.3 1 0 0 1 1 1 1 Up-regulated During Septation DUF2968 PF11180.3 KEP64583.1 - 0.011 15.1 0.7 0.015 14.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TPR_MLP1_2 PF07926.7 KEP64583.1 - 0.014 15.1 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1192 PF06698.6 KEP64583.1 - 0.016 14.9 1.4 0.087 12.6 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) TBPIP PF07106.8 KEP64583.1 - 0.018 14.5 0.3 0.027 14.0 0.0 1.4 2 0 0 2 2 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Microtub_assoc PF07989.6 KEP64583.1 - 0.021 14.6 0.2 0.042 13.6 0.2 1.6 1 0 0 1 1 1 0 Microtubule associated CENP-F_leu_zip PF10473.4 KEP64583.1 - 0.021 14.6 0.3 0.037 13.8 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1640 PF07798.6 KEP64583.1 - 0.025 14.6 0.2 0.049 13.6 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1640) DUF4618 PF15397.1 KEP64583.1 - 0.026 13.8 0.1 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) APG6 PF04111.7 KEP64583.1 - 0.026 13.5 0.3 0.026 13.5 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 KEP64583.1 - 0.031 14.3 0.3 0.17 12.0 0.2 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_HBL PF05791.6 KEP64583.1 - 0.034 13.5 0.2 0.039 13.3 0.1 1.3 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Shugoshin_N PF07558.6 KEP64583.1 - 0.035 13.8 0.3 1.5 8.5 0.0 2.3 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region MbeD_MobD PF04899.7 KEP64583.1 - 0.037 13.9 0.2 0.074 12.9 0.2 1.5 1 0 0 1 1 1 0 MbeD/MobD like FliD_C PF07195.7 KEP64583.1 - 0.039 13.2 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF4200 PF13863.1 KEP64583.1 - 0.042 13.8 0.9 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) YscO PF07321.7 KEP64583.1 - 0.046 13.5 0.4 0.074 12.8 0.3 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO Golgin_A5 PF09787.4 KEP64583.1 - 0.046 12.2 0.3 0.046 12.2 0.2 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF972 PF06156.8 KEP64583.1 - 0.053 13.8 0.5 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) CCDC92 PF14916.1 KEP64583.1 - 0.057 13.0 1.0 5.3 6.7 0.0 2.7 2 1 1 3 3 3 0 Coiled-coil domain of unknown function Spc7 PF08317.6 KEP64583.1 - 0.058 12.0 0.2 0.062 11.9 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein WXG100 PF06013.7 KEP64583.1 - 0.058 13.3 0.3 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF4140 PF13600.1 KEP64583.1 - 0.067 13.6 0.3 0.098 13.1 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3772 PF12607.3 KEP64583.1 - 0.071 12.7 0.8 0.26 10.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Tup_N PF08581.5 KEP64583.1 - 0.075 13.2 0.3 0.2 11.8 0.0 1.8 2 0 0 2 2 1 0 Tup N-terminal DUF2730 PF10805.3 KEP64583.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Clp_N PF02861.15 KEP64583.1 - 0.13 12.2 0.3 16 5.5 0.0 3.2 4 0 0 4 4 3 0 Clp amino terminal domain Cep57_CLD_2 PF14197.1 KEP64583.1 - 0.13 12.1 5.1 1.8 8.5 1.9 2.6 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 Bap31 PF05529.7 KEP64583.1 - 0.13 11.6 0.2 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Cluap1 PF10234.4 KEP64583.1 - 0.14 11.3 2.7 0.082 12.1 0.5 1.7 1 1 1 2 2 2 0 Clusterin-associated protein-1 IncA PF04156.9 KEP64583.1 - 0.14 11.7 1.6 0.16 11.5 1.1 1.3 1 1 0 1 1 1 0 IncA protein Pox_A_type_inc PF04508.7 KEP64583.1 - 0.15 11.9 2.0 14 5.8 0.1 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HalX PF08663.5 KEP64583.1 - 0.15 12.0 3.1 1 9.3 0.5 2.3 1 1 1 2 2 2 0 HalX domain Kinesin-relat_1 PF12711.2 KEP64583.1 - 0.18 12.2 2.1 0.32 11.4 0.6 2.0 2 1 0 2 2 2 0 Kinesin motor V-SNARE PF05008.10 KEP64583.1 - 0.35 11.0 2.5 0.29 11.2 0.4 1.9 2 1 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus DUF1843 PF08898.5 KEP64583.1 - 0.51 10.4 2.8 0.32 11.0 0.5 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF1843) Suf PF05843.9 KEP64585.1 - 1.1e-09 38.4 13.6 6.2e-05 22.8 0.0 5.0 4 2 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_15 PF13429.1 KEP64585.1 - 2.9e-08 33.1 19.7 0.0036 16.3 0.1 5.5 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEP64585.1 - 4.1e-08 33.6 20.2 0.0012 19.4 0.5 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP64585.1 - 1.1e-05 25.3 18.9 2 8.4 0.0 9.3 9 4 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEP64585.1 - 0.01 16.3 41.9 1.7 9.4 0.6 12.7 11 5 4 16 16 16 0 Tetratricopeptide repeat DUF308 PF03729.8 KEP64586.1 - 0.054 13.4 7.4 0.74 9.8 0.0 3.6 4 0 0 4 4 4 0 Short repeat of unknown function (DUF308) Trp_oprn_chp PF09534.5 KEP64586.1 - 0.059 12.9 1.5 0.98 8.9 0.1 2.9 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3628 PF12300.3 KEP64586.1 - 0.16 11.9 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Claudin_2 PF13903.1 KEP64586.1 - 1.3 8.6 16.7 0.097 12.3 4.3 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Abhydrolase_6 PF12697.2 KEP64587.1 - 1.8e-14 54.1 0.1 1.8e-14 54.1 0.1 2.6 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP64587.1 - 8.4e-14 51.5 0.0 2.3e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEP64587.1 - 1.2e-10 41.1 0.9 2.1e-07 30.6 0.0 2.8 3 0 0 3 3 3 2 Putative lysophospholipase Abhydrolase_3 PF07859.8 KEP64587.1 - 9.4e-05 22.0 0.0 0.00025 20.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KEP64587.1 - 0.0027 17.3 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 KEP64587.1 - 0.0089 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) vATP-synt_E PF01991.13 KEP64590.1 - 2.8e-57 193.2 0.9 3.5e-57 192.9 0.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4239 PF14023.1 KEP64590.1 - 0.0014 18.0 5.1 0.0023 17.3 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) CDC37_N PF03234.9 KEP64590.1 - 0.27 11.5 6.1 0.35 11.1 4.0 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF445 PF04286.7 KEP64590.1 - 0.6 9.5 7.5 0.83 9.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4557 PF15101.1 KEP64590.1 - 0.97 9.2 4.4 1.2 8.8 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF848 PF05852.6 KEP64590.1 - 2.3 8.0 10.2 2 8.2 4.9 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF763 PF05559.6 KEP64590.1 - 2.4 7.0 4.8 3.5 6.4 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) ERCC4 PF02732.10 KEP64591.1 - 7.3e-15 54.9 0.0 2.4e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain mRNA_cap_enzyme PF01331.14 KEP64592.1 - 2.3e-38 131.8 0.0 1.4e-25 90.1 0.0 2.2 1 1 1 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KEP64592.1 - 2.4e-09 37.4 0.0 2.3e-07 31.0 0.0 2.5 1 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain HET PF06985.6 KEP64592.1 - 0.0017 18.5 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cyclin PF08613.6 KEP64593.1 - 4.6e-32 111.4 0.2 7.9e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEP64593.1 - 6.4e-08 32.2 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Kelch_3 PF13415.1 KEP64594.1 - 3.1e-20 71.7 4.5 0.00059 19.9 0.0 6.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KEP64594.1 - 3e-18 65.3 4.6 0.004 16.8 0.0 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KEP64594.1 - 9.5e-18 63.7 0.0 0.0021 17.9 0.0 6.0 6 0 0 6 6 6 4 Kelch motif HATPase_c_3 PF13589.1 KEP64594.1 - 2.8e-09 36.7 0.0 6.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.1 KEP64594.1 - 7.3e-06 25.9 0.3 0.017 15.2 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 KEP64594.1 - 0.00011 21.6 0.0 0.12 11.9 0.0 4.0 4 0 0 4 4 4 1 Kelch motif HATPase_c PF02518.21 KEP64594.1 - 0.00017 21.2 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acetyltransf_1 PF00583.19 KEP64595.1 - 9.9e-12 44.7 0.0 1.9e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KEP64595.1 - 0.0001 22.4 0.0 0.00054 20.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEP64595.1 - 0.00053 20.0 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEP64595.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEP64595.1 - 0.0015 18.5 0.0 0.0067 16.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEP64595.1 - 0.017 15.2 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEP64595.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cytochrom_C PF00034.16 KEP64596.1 - 4.7e-05 24.1 0.7 0.00011 22.9 0.2 1.9 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.1 KEP64596.1 - 0.0015 17.9 0.0 0.0098 15.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome_CBB3 PF13442.1 KEP64596.1 - 0.056 13.6 1.1 0.056 13.6 0.8 1.8 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Peptidase_M24 PF00557.19 KEP64597.1 - 2.9e-37 128.2 0.0 3.9e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.8 KEP64597.1 - 0.04 13.5 7.2 0.059 12.9 5.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.7 KEP64597.1 - 0.39 9.0 10.8 0.55 8.5 7.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TATR PF03430.8 KEP64597.1 - 1.2 7.6 2.4 1.6 7.3 1.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Radical_SAM PF04055.16 KEP64599.1 - 3e-14 53.5 0.1 1.1e-13 51.6 0.1 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KEP64599.1 - 1.1e-06 28.5 0.4 3.8e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family CNRIP1 PF15043.1 KEP64599.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 PDCD2_C PF04194.8 KEP64600.1 - 1.7e-36 125.2 1.0 3.3e-36 124.3 0.1 1.9 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain GFO_IDH_MocA PF01408.17 KEP64602.1 - 6.7e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_S5 PF00333.15 KEP64603.1 - 2.1e-28 97.8 0.4 4e-28 96.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KEP64603.1 - 9.9e-21 72.8 0.0 2.1e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 KEP64603.1 - 2.9 8.3 5.7 7.2 7.1 3.9 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TLC PF03219.9 KEP64604.1 - 0.0063 15.0 0.0 0.0084 14.6 0.0 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF1769 PF08588.5 KEP64605.1 - 0.0009 19.1 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Vps51 PF08700.6 KEP64606.1 - 9.6e-19 67.0 0.0 2.6e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 KEP64606.1 - 9.9e-11 41.6 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 KEP64606.1 - 1.4e-05 24.9 1.6 4.1e-05 23.4 1.1 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.7 KEP64606.1 - 0.00019 19.9 0.3 0.00042 18.8 0.2 1.6 1 0 0 1 1 1 1 Dor1-like family M_domain PF12938.2 KEP64607.1 - 0.00044 20.1 0.4 0.00083 19.2 0.3 1.4 1 0 0 1 1 1 1 M domain of GW182 Laminin_II PF06009.7 KEP64607.1 - 0.0013 18.4 7.9 0.052 13.2 0.1 2.5 2 0 0 2 2 2 2 Laminin Domain II Ribonuc_red_lgN PF00317.16 KEP64607.1 - 0.018 14.8 0.2 0.34 10.7 0.0 2.8 2 1 1 3 3 3 0 Ribonucleotide reductase, all-alpha domain DUF2937 PF11157.3 KEP64607.1 - 1.2 8.4 7.9 0.54 9.5 3.6 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) APG6 PF04111.7 KEP64607.1 - 1.9 7.4 26.0 3 6.8 5.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 PEP-utilisers_N PF05524.8 KEP64607.1 - 5.5 6.8 9.7 0.78 9.5 3.7 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Ank_2 PF12796.2 KEP64608.1 - 3.2e-32 110.7 1.4 1.9e-16 60.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEP64608.1 - 2.6e-31 105.8 0.0 1.2e-09 37.5 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 KEP64608.1 - 1.9e-26 91.4 0.3 5.3e-12 45.5 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEP64608.1 - 6.3e-26 90.2 0.4 9.2e-13 48.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP64608.1 - 7.8e-24 81.3 0.5 2.5e-07 30.2 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat MTH865 PF07747.6 KEP64609.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 MTH865-like family ABC_tran PF00005.22 KEP64610.1 - 2.9e-30 105.3 0.0 2.6e-16 60.1 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEP64610.1 - 6.9e-26 91.2 15.9 6.9e-18 65.0 0.6 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_16 PF13191.1 KEP64610.1 - 4.7e-09 36.4 2.4 0.00098 19.1 0.0 3.3 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 KEP64610.1 - 1.2e-07 31.1 0.0 0.0068 15.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEP64610.1 - 1.8e-05 24.6 0.1 0.071 13.0 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 KEP64610.1 - 4e-05 24.0 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KEP64610.1 - 4.8e-05 23.4 0.1 0.0073 16.2 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KEP64610.1 - 5.3e-05 24.0 0.0 0.14 12.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEP64610.1 - 5.3e-05 23.3 0.1 0.22 11.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KEP64610.1 - 0.00016 22.0 0.1 0.45 10.8 0.1 2.9 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 KEP64610.1 - 0.0004 19.2 0.1 0.044 12.5 0.0 2.3 2 0 0 2 2 2 1 ArgK protein Rad17 PF03215.10 KEP64610.1 - 0.00095 17.9 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 KEP64610.1 - 0.001 18.6 0.0 0.021 14.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 KEP64610.1 - 0.001 18.9 0.3 0.17 11.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KEP64610.1 - 0.0015 17.7 0.1 1.9 7.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 KEP64610.1 - 0.0019 17.3 0.1 0.72 8.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 KEP64610.1 - 0.0019 17.6 0.1 0.77 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KEP64610.1 - 0.0023 17.7 0.2 0.0055 16.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_19 PF13245.1 KEP64610.1 - 0.003 17.2 0.1 0.32 10.7 0.0 3.3 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KEP64610.1 - 0.0031 17.6 0.5 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEP64610.1 - 0.0061 15.5 0.1 0.5 9.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KEP64610.1 - 0.0081 15.2 0.0 0.65 9.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 KEP64610.1 - 0.0084 15.0 0.0 0.28 10.0 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 KEP64610.1 - 0.0095 16.4 0.0 0.54 10.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_5 PF07728.9 KEP64610.1 - 0.01 15.5 0.7 1.4 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SMC_N PF02463.14 KEP64610.1 - 0.013 14.7 0.0 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KEP64610.1 - 0.016 15.1 0.2 3.3 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEP64610.1 - 0.03 13.9 0.6 3.2 7.3 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 KEP64610.1 - 0.036 13.4 0.0 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KEP64610.1 - 0.044 13.9 0.1 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 KEP64610.1 - 0.048 13.3 0.1 5 6.8 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 KEP64610.1 - 0.062 12.7 0.1 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KEP64610.1 - 0.067 12.8 0.0 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 KEP64610.1 - 0.084 12.3 0.1 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 KEP64610.1 - 0.11 11.0 0.1 2 6.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 KEP64610.1 - 0.14 11.9 0.0 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.17 KEP64610.1 - 0.15 10.8 0.1 1.7 7.4 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 KEP64610.1 - 0.17 11.3 0.2 20 4.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KEP64610.1 - 0.29 10.8 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KEP64610.1 - 0.36 10.7 0.1 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Imm3 PF14425.1 KEP64613.1 - 0.11 12.4 0.2 0.95 9.4 0.0 2.2 2 1 0 2 2 2 0 Immunity protein Imm3 Rft-1 PF04506.8 KEP64614.1 - 4.3e-15 55.1 0.0 4.6e-07 28.5 0.0 3.3 3 0 0 3 3 3 3 Rft protein LysE PF01810.13 KEP64614.1 - 0.0021 17.3 5.0 0.0037 16.5 0.1 2.8 2 0 0 2 2 2 1 LysE type translocator DUF4234 PF14018.1 KEP64614.1 - 0.063 13.0 0.9 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) F-box-like PF12937.2 KEP64615.1 - 6.1e-06 25.8 4.7 2.6e-05 23.8 3.3 2.2 1 0 0 1 1 1 1 F-box-like Beta-Casp PF10996.3 KEP64617.1 - 2.7e-22 79.0 0.0 6.1e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KEP64617.1 - 3.5e-11 42.7 0.0 9.3e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KEP64617.1 - 1.7e-10 40.9 0.4 7.6e-07 28.9 0.5 3.2 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEP64617.1 - 7.9e-08 32.0 0.0 2.4e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain PBP_sp32 PF07222.7 KEP64617.1 - 0.016 14.4 2.9 0.034 13.3 2.0 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Spore_coat_CotO PF14153.1 KEP64617.1 - 3.1 7.2 14.6 5.5 6.3 10.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Pox_Ag35 PF03286.9 KEP64617.1 - 3.3 7.2 10.3 7.1 6.1 7.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 KEP64617.1 - 5.7 4.5 9.2 7.6 4.0 6.4 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 KEP64617.1 - 6.4 4.6 14.6 12 3.7 10.1 1.4 1 0 0 1 1 1 0 CDC45-like protein NGP1NT PF08153.7 KEP64618.1 - 2.6e-32 111.4 2.8 2.9e-32 111.3 0.1 2.3 2 1 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KEP64618.1 - 4.5e-18 65.2 0.0 1.1e-14 54.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP64618.1 - 6.3e-08 32.0 0.0 0.0032 16.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEP64618.1 - 3.1e-05 23.4 0.0 0.049 13.0 0.0 3.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEP64618.1 - 0.00082 18.5 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arf PF00025.16 KEP64618.1 - 0.0039 16.4 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.18 KEP64618.1 - 0.0067 16.2 4.1 1.1 9.0 1.7 3.8 2 1 0 2 2 2 1 Dynamin family zf-Nse PF11789.3 KEP64619.1 - 7.8e-14 50.9 0.1 1.4e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KEP64619.1 - 0.0096 15.6 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KEP64619.1 - 0.025 14.4 0.1 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Ring finger domain HTH_8 PF02954.14 KEP64619.1 - 0.031 13.8 1.0 3.2 7.3 0.0 2.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family GP46 PF07409.7 KEP64619.1 - 0.078 12.3 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Phage protein GP46 OAD_gamma PF04277.8 KEP64619.1 - 0.22 11.9 4.1 0.11 12.8 0.5 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ABC_tran PF00005.22 KEP64620.1 - 1.4e-15 57.7 0.0 2e-14 54.0 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEP64620.1 - 2e-08 34.5 2.1 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEP64620.1 - 0.0015 17.8 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEP64620.1 - 0.0016 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 KEP64620.1 - 0.0055 16.5 0.1 0.0085 15.9 0.1 1.2 1 0 0 1 1 1 1 Dynamin family DUF258 PF03193.11 KEP64620.1 - 0.006 15.7 0.0 0.0098 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 KEP64620.1 - 0.022 14.1 0.7 0.27 10.6 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 KEP64620.1 - 0.024 13.7 0.0 0.37 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KEP64620.1 - 0.024 14.1 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KEP64620.1 - 0.044 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KEP64620.1 - 0.069 13.6 0.2 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 KEP64620.1 - 0.09 13.5 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEP64620.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEP64620.1 - 0.13 11.6 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEP64620.1 - 0.16 12.2 0.1 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEP64620.1 - 0.22 11.1 2.5 2.4 7.7 0.2 2.7 2 1 2 4 4 4 0 NACHT domain XRN_N PF03159.13 KEP64622.1 - 2.4e-98 328.2 0.0 2.4e-98 328.2 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_4 PF14392.1 KEP64622.1 - 0.06 13.0 0.1 0.19 11.4 0.1 1.9 1 0 0 1 1 1 0 Zinc knuckle Spore_coat_CotO PF14153.1 KEP64622.1 - 5.3 6.4 10.3 1.1 8.7 1.3 2.5 2 0 0 2 2 2 0 Spore coat protein CotO DSPc PF00782.15 KEP64623.1 - 0.00027 20.5 0.1 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEP64623.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KEP64623.1 - 0.025 14.8 0.0 0.025 14.8 0.0 2.3 2 0 0 2 2 2 0 Tyrosine phosphatase family PTPS PF01242.14 KEP64624.1 - 7.8e-21 74.0 0.0 1.8e-20 72.8 0.0 1.6 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase X PF00739.14 KEP64624.1 - 0.12 12.2 5.8 0.29 11.0 4.0 1.7 1 0 0 1 1 1 0 Trans-activation protein X DUF4129 PF13559.1 KEP64625.1 - 0.16 11.9 4.0 0.39 10.7 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) CS PF04969.11 KEP64626.1 - 2.9e-14 53.3 0.4 5.5e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 CS domain SGS PF05002.10 KEP64626.1 - 2.9e-13 49.3 2.1 6.8e-13 48.1 1.4 1.6 1 0 0 1 1 1 1 SGS domain DotA PF11388.3 KEP64626.1 - 0.014 15.4 0.1 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Phagosome trafficking protein DotA Siah-Interact_N PF09032.6 KEP64626.1 - 0.07 13.2 0.6 0.17 11.9 0.2 2.0 1 1 0 1 1 1 0 Siah interacting protein, N terminal EF-hand_1 PF00036.27 KEP64627.1 - 7.7e-11 40.4 1.3 2.3e-05 23.3 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KEP64627.1 - 7.8e-11 41.9 2.4 0.00018 21.5 0.9 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP64627.1 - 2.9e-09 36.0 3.8 0.0091 15.8 0.3 3.4 2 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KEP64627.1 - 6.9e-08 31.9 1.6 0.00014 21.3 0.1 3.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KEP64627.1 - 1.1e-05 24.5 5.3 8.2e-05 21.7 0.2 3.7 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 KEP64627.1 - 0.037 14.0 0.0 1.5 8.8 0.0 2.1 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CTP_transf_2 PF01467.21 KEP64628.1 - 1.5e-16 60.8 0.0 6.4e-14 52.2 0.0 2.4 1 1 0 1 1 1 1 Cytidylyltransferase RRM_1 PF00076.17 KEP64629.1 - 4.3e-19 67.9 0.0 4.6e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64629.1 - 7.4e-16 57.8 0.0 1.4e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64629.1 - 1.7e-08 34.1 0.0 6e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEP64629.1 - 0.00011 21.8 0.0 0.00055 19.6 0.0 2.0 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KEP64629.1 - 0.0019 17.8 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 Limkain b1 Pkinase PF00069.20 KEP64630.1 - 7.9e-79 264.4 0.0 1.1e-78 264.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64630.1 - 1.2e-42 145.7 0.1 7.5e-42 143.1 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP64630.1 - 2.1e-28 95.4 5.9 1.9e-07 29.8 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 KEP64630.1 - 2.4e-23 80.3 3.3 2.5e-06 26.5 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KEP64630.1 - 2.6e-22 76.6 3.4 3.6e-05 23.2 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KEP64630.1 - 4.3e-22 78.0 11.5 2.9e-10 40.1 0.5 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 KEP64630.1 - 7.6e-15 54.2 9.5 4.5e-06 26.1 1.2 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEP64630.1 - 4.9e-07 29.7 2.6 0.012 15.5 0.2 2.8 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KEP64630.1 - 2.1e-06 27.3 5.5 0.00043 19.9 0.3 3.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 KEP64630.1 - 6.4e-06 25.3 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like EF-hand_10 PF14788.1 KEP64630.1 - 1.4e-05 24.6 2.6 0.041 13.5 0.3 4.2 4 1 1 5 5 5 2 EF hand APH PF01636.18 KEP64630.1 - 0.013 15.2 0.0 0.047 13.4 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEP64630.1 - 0.09 11.8 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAD PF02109.11 KEP64631.1 - 2.6e-29 101.5 3.9 3.4e-29 101.1 2.7 1.1 1 0 0 1 1 1 1 DAD family PT PF04886.7 KEP64632.1 - 2.1e-08 33.3 49.4 3.6e-05 22.9 4.0 18.2 20 1 1 21 21 21 8 PT repeat SlyX PF04102.7 KEP64634.1 - 0.062 13.6 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 SlyX PH PF00169.24 KEP64634.1 - 0.11 12.7 0.1 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 PH domain Rhodanese PF00581.15 KEP64636.1 - 3.5e-14 53.1 0.0 2.6e-05 24.5 0.0 3.9 4 0 0 4 4 4 3 Rhodanese-like domain HhH-GPD PF00730.20 KEP64637.1 - 7e-22 77.7 0.0 1.2e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KEP64637.1 - 1.3e-07 30.9 0.0 3.4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KEP64637.1 - 0.044 13.9 0.1 1.3 9.2 0.0 3.2 5 0 0 5 5 5 0 Helix-hairpin-helix domain Pro_isomerase PF00160.16 KEP64639.1 - 5.8e-42 143.5 0.4 1.3e-41 142.3 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KEP64639.1 - 4.2e-09 36.0 0.5 4.2e-09 36.0 0.4 2.6 2 1 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.3 KEP64639.1 - 0.0028 17.1 0.8 0.47 10.0 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 KEP64639.1 - 0.022 14.6 0.0 0.15 12.0 0.0 2.3 1 1 2 3 3 3 0 U-box domain TPR_11 PF13414.1 KEP64640.1 - 3.9e-18 64.8 2.4 5.6e-07 29.1 0.1 4.3 4 1 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 KEP64640.1 - 3.4e-14 51.5 10.7 0.011 15.6 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP64640.1 - 1e-09 37.5 0.9 0.23 11.1 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEP64640.1 - 4e-09 36.2 14.2 0.035 14.7 0.6 6.7 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KEP64640.1 - 6.7e-07 29.1 6.2 0.63 10.0 0.2 5.2 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEP64640.1 - 1e-06 28.0 5.5 0.55 10.1 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEP64640.1 - 3.3e-06 27.5 25.7 0.017 15.8 3.8 6.2 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEP64640.1 - 0.00011 22.4 4.5 0.44 10.9 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP64640.1 - 0.00034 20.4 12.8 0.05 13.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP64640.1 - 0.0014 18.6 0.0 11 6.4 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.5 KEP64640.1 - 0.02 13.6 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.1 KEP64640.1 - 0.05 13.3 0.0 56 3.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Pyr_redox_dim PF02852.17 KEP64641.1 - 8.5e-31 106.2 1.3 3.6e-30 104.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KEP64641.1 - 4.3e-27 95.3 0.0 1.2e-26 93.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEP64641.1 - 8.1e-14 51.7 2.2 3.9e-13 49.6 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEP64641.1 - 3.5e-05 22.8 1.4 5.2e-05 22.2 1.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 KEP64641.1 - 0.00033 20.0 1.4 0.00039 19.8 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KEP64641.1 - 0.00048 19.8 0.2 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KEP64641.1 - 0.0013 17.6 5.2 0.0024 16.7 1.9 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KEP64641.1 - 0.0013 17.7 7.0 0.0022 16.9 0.8 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KEP64641.1 - 0.013 15.0 0.2 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KEP64641.1 - 0.015 14.4 0.0 1.7 7.7 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KEP64641.1 - 0.016 14.3 5.2 0.032 13.3 3.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEP64641.1 - 0.023 13.6 0.0 0.37 9.6 0.0 2.2 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AP2 PF00847.15 KEP64642.1 - 2.8e-15 56.1 14.3 5e-07 29.7 0.3 3.5 3 0 0 3 3 3 3 AP2 domain ACDC PF14733.1 KEP64642.1 - 2.7e-08 33.8 0.2 6.7e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 AP2-coincident C-terminal Pol_alpha_B_N PF08418.5 KEP64642.1 - 1 8.8 4.2 5 6.5 2.9 2.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Chorein_N PF12624.2 KEP64643.1 - 1.3e-25 89.1 0.0 2.5e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 KEP64643.1 - 1.2e-07 31.2 0.0 3e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Mt_ATP-synt_D PF05873.7 KEP64643.1 - 4.6 6.8 0.0 12 5.5 0.0 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Apt1 PF10351.4 KEP64643.1 - 6.3 5.5 8.2 0.35 9.6 0.0 2.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain GST_N_3 PF13417.1 KEP64644.1 - 3.4e-14 52.8 0.5 8.4e-09 35.5 0.0 3.1 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEP64644.1 - 3.8e-07 30.0 0.0 1.2e-05 25.1 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KEP64644.1 - 0.0011 18.8 0.2 0.012 15.5 0.3 2.2 2 0 0 2 2 2 1 Glutaredoxin zf-CHY PF05495.7 KEP64645.1 - 9.4e-17 60.9 21.5 1.2e-15 57.4 6.6 3.6 3 0 0 3 3 3 2 CHY zinc finger Myb_DNA-binding PF00249.26 KEP64645.1 - 4.6e-05 23.3 1.0 4.6e-05 23.3 0.7 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEP64645.1 - 0.00044 20.2 0.1 0.0011 19.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fasciclin PF02469.17 KEP64646.1 - 1.6e-08 34.5 0.0 2.8e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain DUF4201 PF13870.1 KEP64648.1 - 8.1e-26 90.5 18.0 9.3e-26 90.3 12.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Chibby PF14645.1 KEP64648.1 - 0.48 10.3 5.4 0.62 9.9 2.9 1.8 1 1 1 2 2 2 0 Chibby family MCM_N PF14551.1 KEP64648.1 - 0.61 10.5 4.5 0.9 10.0 3.1 1.4 1 1 0 1 1 1 0 MCM N-terminal domain ALMT PF11744.3 KEP64648.1 - 0.7 8.4 3.7 0.81 8.2 2.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SPOUT_MTase PF02590.12 KEP64648.1 - 2.1 8.0 5.7 7.1 6.3 0.0 2.8 1 1 3 4 4 4 0 Predicted SPOUT methyltransferase Helicase_C PF00271.26 KEP64649.1 - 3.6e-19 68.4 0.0 1.4e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KEP64649.1 - 3.7e-15 55.8 0.0 8.1e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 KEP64649.1 - 1.2e-07 31.3 0.0 3.4e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 KEP64649.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EF-hand_8 PF13833.1 KEP64649.1 - 0.22 11.1 0.1 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair DUF1764 PF08576.5 KEP64651.1 - 3.2e-21 76.0 5.4 3.2e-21 76.0 3.7 2.8 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Nucleo_P87 PF07267.6 KEP64651.1 - 5.6 5.5 8.4 6.7 5.2 5.8 1.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mei5 PF10376.4 KEP64652.1 - 0.086 12.3 0.6 0.1 12.1 0.5 1.0 1 0 0 1 1 1 0 Double-strand recombination repair protein CDC73 PF05179.9 KEP64653.1 - 4.1e-22 78.8 0.0 8.3e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family FF PF01846.14 KEP64654.1 - 2.3e-16 59.4 5.3 1.7e-11 43.9 0.0 3.8 3 0 0 3 3 3 2 FF domain WW PF00397.21 KEP64654.1 - 1.7e-12 46.9 13.1 2.2e-10 40.1 1.1 2.9 2 0 0 2 2 2 2 WW domain Nop14 PF04147.7 KEP64658.1 - 1.6 6.5 6.3 1.6 6.5 4.4 1.0 1 0 0 1 1 1 0 Nop14-like family IspD PF01128.14 KEP64660.1 - 1.8e-20 73.3 5.5 6.9e-08 32.2 0.4 5.0 5 0 0 5 5 5 4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4602 PF15375.1 KEP64660.1 - 0.063 13.3 0.0 0.22 11.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) PI3K_C2 PF00792.19 KEP64661.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 Phosphoinositide 3-kinase C2 Med7 PF05983.6 KEP64662.1 - 5.6e-15 55.4 0.0 6.4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 MED7 protein RNA_pol_Rpb1_5 PF04998.12 KEP64663.1 - 2.5e-94 315.6 0.0 4.3e-94 314.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KEP64663.1 - 8.5e-77 258.6 0.0 1.2e-76 258.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KEP64663.1 - 1.2e-66 223.8 0.0 4.8e-66 221.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KEP64663.1 - 3.4e-34 117.8 0.0 8.9e-34 116.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KEP64663.1 - 5.9e-30 103.1 0.0 1.4e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Pol_alpha_B_N PF08418.5 KEP64663.1 - 0.37 10.2 4.3 0.7 9.3 3.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SR-25 PF10500.4 KEP64663.1 - 0.64 9.4 7.6 1.1 8.6 5.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SMC_N PF02463.14 KEP64665.1 - 1e-41 142.5 0.0 6.6e-41 139.9 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEP64665.1 - 1.7e-11 44.8 21.9 1.7e-11 44.8 15.2 7.4 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KEP64665.1 - 5.6e-10 39.6 0.0 2.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_hinge PF06470.8 KEP64665.1 - 5.9e-10 39.1 0.0 1.3e-08 34.7 0.0 3.2 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.1 KEP64665.1 - 2e-08 33.6 0.0 0.00014 21.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KEP64665.1 - 0.0032 16.9 5.3 0.22 10.8 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KEP64665.1 - 0.012 15.0 0.1 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEP64665.1 - 1.2 9.4 0.0 0.25 11.6 0.1 5.9 6 2 0 6 6 6 0 ABC transporter Myb_DNA-binding PF00249.26 KEP64666.1 - 2.9e-14 52.8 0.6 6.2e-14 51.7 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain MIP-T3 PF10243.4 KEP64666.1 - 0.00014 20.5 20.9 0.00014 20.5 14.5 4.3 4 1 0 4 4 4 1 Microtubule-binding protein MIP-T3 Rrn6 PF10214.4 KEP64666.1 - 0.75 7.8 4.6 1.5 6.8 3.2 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Abhydrolase_5 PF12695.2 KEP64667.1 - 6.9e-09 35.6 0.0 1.6e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP64667.1 - 1.8e-07 31.2 0.0 3.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEP64667.1 - 4.5e-05 23.2 0.5 0.21 11.4 0.0 2.4 2 0 0 2 2 2 2 Putative lysophospholipase UPF0227 PF05728.7 KEP64667.1 - 0.0019 17.9 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Mitofilin PF09731.4 KEP64667.1 - 2.4 6.6 15.8 4.5 5.7 10.9 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dynein_heavy PF03028.10 KEP64669.1 - 1.4e-194 648.1 0.0 1.4e-194 648.1 0.0 2.5 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 KEP64669.1 - 8e-128 427.3 7.7 8e-128 427.3 5.3 3.5 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KEP64669.1 - 5.2e-115 384.2 6.0 5.2e-115 384.2 4.2 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEP64669.1 - 5.7e-91 304.1 0.1 1.7e-89 299.3 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KEP64669.1 - 2.4e-71 239.8 0.0 7.1e-71 238.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEP64669.1 - 9.6e-54 181.6 0.9 1.9e-53 180.6 0.6 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KEP64669.1 - 2.6e-41 141.5 15.7 2.6e-41 141.5 10.9 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KEP64669.1 - 8.1e-38 130.0 0.0 2.2e-37 128.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KEP64669.1 - 9.6e-19 67.4 0.0 1.6e-06 27.8 0.0 5.1 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 KEP64669.1 - 8.3e-08 32.4 1.2 0.55 10.4 0.0 6.5 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEP64669.1 - 0.00036 21.3 0.0 0.49 11.2 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 KEP64669.1 - 0.13 12.0 5.3 25 4.7 0.5 4.5 4 0 0 4 4 4 0 Part of AAA domain Med15_fungi PF05397.7 KEP64671.1 - 0.038 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 15 IncA PF04156.9 KEP64671.1 - 0.11 12.0 8.6 0.013 15.1 2.9 1.6 2 0 0 2 2 2 0 IncA protein zf-U1 PF06220.7 KEP64672.1 - 1.8e-18 65.8 2.3 2.5e-18 65.3 1.6 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KEP64672.1 - 0.00056 19.9 0.7 0.0011 19.0 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding COX6B PF02297.12 KEP64673.1 - 0.0011 18.9 3.9 0.0018 18.2 2.7 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sec34 PF04136.10 KEP64675.1 - 2.1e-12 47.0 0.0 9.3e-08 31.9 0.0 2.6 2 0 0 2 2 2 2 Sec34-like family LPP PF04728.8 KEP64676.1 - 0.29 10.9 3.7 1.1 9.0 0.1 2.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper ATG16 PF08614.6 KEP64676.1 - 2.3 8.0 57.7 0.42 10.4 8.1 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KEP64676.1 - 4.3 6.4 10.0 0.082 12.0 1.4 2.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein ORC5_C PF14630.1 KEP64677.1 - 0.019 14.4 0.8 0.034 13.6 0.6 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus UBA PF00627.26 KEP64677.1 - 0.021 14.6 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain Nucleoplasmin PF03066.10 KEP64677.1 - 0.021 14.3 7.6 0.022 14.2 0.0 2.4 2 0 0 2 2 2 0 Nucleoplasmin SPX PF03105.14 KEP64677.1 - 5.2 6.7 16.1 32 4.1 0.5 3.0 2 1 0 2 2 2 0 SPX domain adh_short_C2 PF13561.1 KEP64678.1 - 1.8e-29 103.2 0.1 2e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEP64678.1 - 8.4e-17 61.5 5.6 1.2e-16 61.1 3.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEP64678.1 - 3e-05 23.7 3.0 4.7e-05 23.1 1.8 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 KEP64678.1 - 0.032 14.4 0.0 0.044 14.0 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KEP64678.1 - 0.047 13.6 0.3 0.28 11.1 0.0 2.2 3 0 0 3 3 3 0 NADH(P)-binding DUF1510 PF07423.6 KEP64679.1 - 0.00057 19.3 0.3 0.00066 19.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) ETRAMP PF09716.5 KEP64679.1 - 0.018 14.9 0.7 0.025 14.4 0.5 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF1411 PF07199.6 KEP64679.1 - 0.026 13.9 0.1 0.027 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Peptidase_S49_N PF08496.5 KEP64679.1 - 0.029 14.1 1.0 0.031 14.0 0.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.4 KEP64679.1 - 0.038 13.6 13.0 0.043 13.5 9.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TRAP_alpha PF03896.11 KEP64679.1 - 0.043 12.8 0.1 0.047 12.6 0.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CagX PF03524.10 KEP64679.1 - 0.067 12.4 0.5 0.069 12.4 0.4 1.1 1 0 0 1 1 1 0 Conjugal transfer protein DUF4557 PF15101.1 KEP64679.1 - 0.067 13.0 0.1 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pro-rich PF15240.1 KEP64679.1 - 0.074 13.1 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Proline-rich BLVR PF06375.6 KEP64679.1 - 0.098 12.4 9.3 0.11 12.3 6.5 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNA_polI_A34 PF08208.6 KEP64679.1 - 0.21 11.2 11.7 0.24 11.0 8.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GRP PF07172.6 KEP64679.1 - 1.6 9.2 4.1 2.8 8.4 2.8 1.4 1 1 0 1 1 1 0 Glycine rich protein family Bromodomain PF00439.20 KEP64680.1 - 8.8e-20 70.4 1.0 2.5e-19 68.9 0.3 1.9 2 0 0 2 2 2 1 Bromodomain BRI3BP PF14965.1 KEP64680.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF4041 PF13250.1 KEP64680.1 - 0.33 10.5 0.4 0.69 9.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) ICMT PF04140.9 KEP64681.1 - 1.4e-20 73.2 0.2 3e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KEP64681.1 - 1.2e-10 41.4 1.7 3.6e-10 39.8 1.2 1.9 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.6 KEP64681.1 - 0.0018 17.6 0.4 0.0018 17.6 0.3 2.3 2 1 0 2 2 2 1 NnrU protein Pkinase PF00069.20 KEP64682.1 - 4.9e-65 219.2 0.0 3.9e-36 124.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64682.1 - 8.1e-28 97.1 0.0 4e-18 65.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP64682.1 - 0.045 12.6 0.2 7.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Chlam_OMP PF01308.12 KEP64682.1 - 0.068 11.7 0.2 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Chlamydia major outer membrane protein Kdo PF06293.9 KEP64682.1 - 0.097 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KEP64682.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KEP64682.1 - 0.45 9.8 0.1 0.82 8.9 0.1 1.3 1 0 0 1 1 1 0 RIO1 family BSD PF03909.12 KEP64683.1 - 0.00012 21.6 0.4 0.00023 20.8 0.3 1.4 1 0 0 1 1 1 1 BSD domain ADIP PF11559.3 KEP64683.1 - 0.022 14.6 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TruB_N PF01509.13 KEP64686.1 - 3.2e-40 137.7 0.0 3.9e-35 121.1 0.0 2.2 2 0 0 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) Choline_kinase PF01633.15 KEP64688.1 - 1.4e-34 119.5 0.0 3.8e-34 118.1 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KEP64688.1 - 1.4e-16 60.9 0.5 4.3e-16 59.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEP64688.1 - 4.5e-05 22.7 0.0 8.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 KEP64688.1 - 0.025 13.5 0.0 0.16 10.9 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase GHMP_kinases_N PF00288.21 KEP64689.1 - 8.8 6.4 11.6 0.24 11.4 1.5 2.8 2 0 0 2 2 2 0 GHMP kinases N terminal domain Nucleoporin_FG PF13634.1 KEP64691.1 - 1.1e-32 112.5 163.6 1.7e-10 41.0 29.7 6.2 3 2 3 6 6 6 6 Nucleoporin FG repeat region Lzipper-MIP1 PF14389.1 KEP64691.1 - 0.016 15.3 2.6 0.016 15.3 1.8 2.4 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Nbl1_Borealin_N PF10444.4 KEP64691.1 - 0.025 13.9 0.4 0.071 12.4 0.3 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal DUF59 PF01883.14 KEP64694.1 - 0.0011 18.9 0.0 0.72 9.8 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function DUF59 CDC45 PF02724.9 KEP64694.1 - 2.9 5.8 7.5 4.8 5.0 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 KEP64695.1 - 3.8e-15 55.2 0.0 6.6e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64695.1 - 6.9e-12 45.0 0.0 1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64695.1 - 1.8e-11 43.8 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_PH PF01138.16 KEP64696.1 - 3.5e-22 79.1 0.0 8.6e-22 77.8 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 AP2 PF00847.15 KEP64697.1 - 6.9e-09 35.7 3.6 1.4e-08 34.7 1.6 2.1 2 0 0 2 2 2 1 AP2 domain GCD14 PF08704.5 KEP64699.1 - 2e-68 230.5 0.0 2.9e-41 141.6 0.0 3.4 3 0 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 KEP64699.1 - 0.00027 21.4 0.0 0.00075 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEP64699.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KEP64699.1 - 0.039 13.9 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 KEP64699.1 - 0.24 12.2 1.1 1.1 10.1 0.8 2.2 1 1 0 1 1 1 0 Methyltransferase domain V-SNARE_C PF12352.3 KEP64700.1 - 1.7e-07 31.2 0.9 4.1e-07 29.9 0.6 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEP64700.1 - 0.0012 18.4 0.2 0.0012 18.4 0.1 2.1 2 0 0 2 2 2 1 Sec20 Calpain_inhib PF00748.14 KEP64700.1 - 0.014 15.7 0.6 0.049 13.9 0.4 1.9 1 0 0 1 1 1 0 Calpain inhibitor FadA PF09403.5 KEP64700.1 - 0.02 14.9 1.6 0.02 14.9 1.1 2.4 2 1 0 2 2 2 0 Adhesion protein FadA Apolipoprotein PF01442.13 KEP64700.1 - 0.022 14.2 15.2 0.43 10.0 1.2 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SNARE PF05739.14 KEP64700.1 - 0.023 14.3 2.2 0.023 14.3 1.5 2.5 2 1 0 2 2 2 0 SNARE domain DUF640 PF04852.7 KEP64700.1 - 0.028 14.5 0.1 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF640) MCPsignal PF00015.16 KEP64700.1 - 0.043 13.3 6.4 1.4 8.4 0.3 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain V-SNARE PF05008.10 KEP64700.1 - 0.044 13.9 10.0 0.043 13.9 1.6 3.2 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF2884 PF11101.3 KEP64700.1 - 0.082 12.2 7.5 0.087 12.1 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Phasin PF05597.6 KEP64700.1 - 0.12 12.1 6.2 0.066 12.9 0.7 2.4 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Prominin PF05478.6 KEP64700.1 - 0.16 9.4 2.4 0.48 7.9 0.1 2.0 2 0 0 2 2 2 0 Prominin Baculo_PEP_C PF04513.7 KEP64700.1 - 0.18 11.6 6.5 0.21 11.4 0.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PTRF_SDPR PF15237.1 KEP64700.1 - 0.33 10.3 7.8 0.17 11.2 0.4 2.2 1 1 1 3 3 3 0 PTRF/SDPR family Myosin_tail_1 PF01576.14 KEP64700.1 - 0.5 8.0 15.5 0.28 8.8 2.0 2.1 2 0 0 2 2 2 0 Myosin tail Laminin_II PF06009.7 KEP64700.1 - 6.8 6.4 11.8 5.4 6.7 2.0 2.7 2 1 1 3 3 3 0 Laminin Domain II AlkA_N PF06029.6 KEP64701.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AlkA N-terminal domain PseudoU_synth_2 PF00849.17 KEP64702.1 - 1.4e-17 64.0 0.0 2.7e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase MATH PF00917.21 KEP64702.1 - 0.00015 22.0 0.1 0.00027 21.1 0.1 1.4 1 0 0 1 1 1 1 MATH domain USP7_ICP0_bdg PF12436.3 KEP64702.1 - 0.62 9.2 0.0 1 8.5 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Pro_dh-DNA_bdg PF14850.1 KEP64702.1 - 0.65 10.2 0.0 1.3 9.1 0.0 1.5 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase Phosducin PF02114.11 KEP64702.1 - 1.6 7.4 0.1 2.9 6.5 0.1 1.3 1 0 0 1 1 1 0 Phosducin B12D PF06522.6 KEP64703.1 - 0.00019 21.0 0.5 0.00047 19.7 0.1 2.0 2 1 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PBP1_TM PF14812.1 KEP64706.1 - 8.2 6.8 8.8 18 5.7 6.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DnaJ PF00226.26 KEP64708.1 - 1.5e-15 56.7 0.5 3.8e-15 55.3 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain CAF-1_p150 PF11600.3 KEP64709.1 - 0.00042 19.7 27.5 0.00042 19.7 19.1 3.3 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PCI PF01399.22 KEP64709.1 - 0.06 13.6 0.1 0.06 13.6 0.1 3.5 3 0 0 3 3 3 0 PCI domain BT1 PF03092.11 KEP64710.1 - 2.6e-62 210.9 14.9 3.8e-62 210.4 10.3 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 KEP64710.1 - 0.00064 18.5 1.1 0.00064 18.5 0.7 4.3 1 1 2 3 3 3 2 Major Facilitator Superfamily WD40 PF00400.27 KEP64711.1 - 1.2e-45 151.8 16.4 1.8e-09 37.0 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40 PF00400.27 KEP64712.1 - 7.2e-28 95.4 7.5 2.9e-08 33.2 0.1 7.4 6 2 0 6 6 6 4 WD domain, G-beta repeat CENP-B_dimeris PF09026.5 KEP64712.1 - 0.0011 19.1 4.0 0.0011 19.1 2.8 2.7 2 1 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.1 KEP64712.1 - 2.6 7.7 10.3 0.12 12.1 1.3 2.5 2 0 0 2 2 2 0 FAM176 family Myc_N PF01056.13 KEP64712.1 - 6.2 5.8 9.7 2 7.4 4.8 1.6 1 1 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 KEP64712.1 - 7.1 5.8 18.2 15 4.7 12.6 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Methyltransf_PK PF05891.7 KEP64713.1 - 2.8e-69 232.7 0.0 3.4e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KEP64713.1 - 3.7e-05 24.2 0.1 9.5e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP64713.1 - 0.00023 21.5 0.0 0.00042 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KEP64713.1 - 0.00034 19.8 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 KEP64713.1 - 0.0004 20.8 0.0 0.00069 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP64713.1 - 0.0019 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP64713.1 - 0.0028 17.9 0.1 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF605 PF04652.11 KEP64713.1 - 4.8 6.4 7.5 6.7 5.9 5.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF260 PF03195.9 KEP64714.1 - 0.2 11.9 1.4 0.25 11.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF260 REV PF00424.13 KEP64715.1 - 0.066 13.1 0.9 0.18 11.7 0.7 1.7 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Xpo1 PF08389.7 KEP64715.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Exportin 1-like protein DivIC PF04977.10 KEP64715.1 - 1.3 8.5 4.7 3.1 7.3 0.3 2.8 3 0 0 3 3 3 0 Septum formation initiator Phosphoprotein PF00922.12 KEP64715.1 - 3.7 6.6 10.2 5.7 6.0 1.5 2.5 3 0 0 3 3 3 0 Vesiculovirus phosphoprotein Tctex-1 PF03645.8 KEP64716.1 - 3e-20 71.9 0.1 3.5e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family Cullin PF00888.17 KEP64718.1 - 2.8e-137 458.7 0.0 3.7e-137 458.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEP64718.1 - 2.3e-25 88.2 3.0 3.4e-25 87.6 1.4 1.8 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2217 PF10265.4 KEP64718.1 - 0.17 10.6 19.6 0.064 12.0 5.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) DUF4614 PF15391.1 KEP64718.1 - 7.1 6.3 30.9 0.4 10.4 10.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) VWA PF00092.23 KEP64719.1 - 2e-40 138.3 0.0 3e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 KEP64719.1 - 3.3e-34 116.7 75.7 7.7e-09 35.5 5.3 8.3 7 2 0 7 7 7 6 Thrombospondin type 1 domain VWA_2 PF13519.1 KEP64719.1 - 4.8e-08 33.2 0.0 7.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FHA PF00498.21 KEP64720.1 - 4.2e-16 58.8 0.0 1.1e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Thioredoxin PF00085.15 KEP64721.1 - 2.7e-05 23.7 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 KEP64721.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Ribosomal_L37 PF08561.5 KEP64724.1 - 2.4e-14 52.6 0.0 5e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Asp PF00026.18 KEP64725.1 - 1.5e-78 264.2 0.0 7e-68 229.2 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEP64725.1 - 6.7e-06 26.1 0.2 2.7e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEP64725.1 - 0.0098 16.3 0.3 2.1 8.9 0.0 3.3 2 1 0 2 2 2 1 Aspartyl protease A1_Propeptide PF07966.7 KEP64725.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 A1 Propeptide LDB19 PF13002.2 KEP64725.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like WD40 PF00400.27 KEP64726.1 - 8.8e-30 101.4 28.2 9.8e-06 25.2 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KEP64726.1 - 0.00039 18.7 0.7 0.44 8.6 0.1 3.2 2 1 0 3 3 3 3 Nucleoporin Nup120/160 DUF1510 PF07423.6 KEP64727.1 - 0.012 15.0 4.3 0.014 14.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TPR_11 PF13414.1 KEP64728.1 - 4.9e-13 48.5 9.2 2.3e-05 23.9 0.1 4.8 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.1 KEP64728.1 - 1e-08 35.6 28.0 1.3e-08 35.2 3.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEP64728.1 - 1.4e-05 25.2 13.2 0.0023 18.2 0.5 4.5 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP64728.1 - 0.0032 17.0 11.7 0.099 12.2 0.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP64728.1 - 0.007 16.2 0.8 0.007 16.2 0.6 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP64728.1 - 0.0081 15.8 2.8 0.25 11.2 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP64728.1 - 0.038 14.2 4.2 2.9 8.3 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP64728.1 - 0.4 11.4 30.8 0.16 12.7 0.6 7.4 5 2 3 8 8 8 0 Tetratricopeptide repeat TPR_15 PF13429.1 KEP64728.1 - 0.74 8.8 9.0 6.2 5.8 0.5 3.3 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP64728.1 - 1.1 9.3 19.5 0.29 11.1 0.4 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEP64728.1 - 2.9 8.0 9.8 5.9 7.0 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat UCR_UQCRX_QCR9 PF05365.7 KEP64729.1 - 8.6e-07 28.4 0.5 1.4e-06 27.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ribosomal_L37 PF08561.5 KEP64729.1 - 0.076 12.5 1.3 0.16 11.5 0.9 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 MORN PF02493.15 KEP64730.1 - 2e-39 131.0 41.1 2.4e-07 30.0 0.0 8.8 9 0 0 9 9 9 7 MORN repeat DUF3086 PF11285.3 KEP64730.1 - 0.053 12.3 0.2 0.67 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Prothymosin PF03247.9 KEP64731.1 - 0.93 9.6 13.2 2 8.6 9.1 1.6 1 1 0 1 1 1 0 Prothymosin/parathymosin family Daxx PF03344.10 KEP64731.1 - 1 7.7 15.2 1.1 7.6 10.5 1.0 1 0 0 1 1 1 0 Daxx Family SR-25 PF10500.4 KEP64731.1 - 9.1 5.6 24.2 0.42 10.0 12.6 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAM-associated PF14303.1 KEP64732.1 - 0.0055 17.0 0.7 0.013 15.7 0.5 1.7 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Flagellin_N PF00669.15 KEP64732.1 - 0.041 13.6 2.3 0.87 9.3 0.2 2.8 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region OmpH PF03938.9 KEP64732.1 - 0.19 11.6 4.6 0.32 10.9 3.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IFT20 PF14931.1 KEP64732.1 - 0.2 11.5 6.7 0.027 14.3 1.7 1.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2664 PF10867.3 KEP64732.1 - 0.25 11.9 4.0 0.78 10.3 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) IncA PF04156.9 KEP64732.1 - 0.63 9.5 8.0 0.08 12.5 1.6 2.4 3 0 0 3 3 3 0 IncA protein COG2 PF06148.6 KEP64732.1 - 0.79 9.5 4.3 1.6 8.6 3.0 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.1 KEP64732.1 - 1.4 9.3 8.8 0.15 12.4 1.8 2.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) HSP70 PF00012.15 KEP64734.1 - 1.4e-12 46.3 1.1 7.5e-08 30.7 0.1 2.9 3 0 0 3 3 3 2 Hsp70 protein TPR_11 PF13414.1 KEP64734.1 - 1.1e-07 31.3 4.0 1.3e-07 31.1 0.6 2.6 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEP64734.1 - 0.0011 18.7 0.1 0.064 13.2 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEP64734.1 - 0.0039 17.0 0.1 0.074 12.9 0.0 3.0 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 KEP64734.1 - 0.0046 16.5 0.2 2.4 7.9 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP64734.1 - 0.0071 16.4 0.4 0.028 14.5 0.3 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat HEPN PF05168.9 KEP64734.1 - 0.0088 15.9 0.2 0.05 13.4 0.0 2.2 2 0 0 2 2 2 1 HEPN domain TPR_19 PF14559.1 KEP64734.1 - 0.019 15.2 0.6 0.019 15.2 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MHC_II_alpha PF00993.15 KEP64734.1 - 0.087 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain TPR_14 PF13428.1 KEP64734.1 - 1.1 10.0 4.6 1 10.1 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat PARP PF00644.15 KEP64736.1 - 2.5e-10 40.1 0.0 3.6e-07 29.8 0.0 3.6 3 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain RskA PF10099.4 KEP64738.1 - 0.053 13.2 1.8 0.081 12.6 1.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA BatD PF13584.1 KEP64738.1 - 0.12 10.9 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance RAP PF08373.5 KEP64740.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 RAP domain FlxA PF14282.1 KEP64740.1 - 0.4 10.6 0.0 0.4 10.6 0.0 3.0 4 0 0 4 4 4 0 FlxA-like protein PH PF00169.24 KEP64744.1 - 3.1e-12 46.6 0.1 0.077 13.1 0.0 5.8 5 2 1 6 6 6 4 PH domain ECH PF00378.15 KEP64745.1 - 3.2e-45 154.1 0.0 5.4e-24 84.6 0.0 3.1 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase family ABC1 PF03109.11 KEP64746.1 - 5e-31 107.1 0.3 9.8e-31 106.1 0.2 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KEP64746.1 - 0.15 11.8 7.0 0.052 13.2 0.3 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEP64746.1 - 0.16 11.2 0.1 0.44 9.8 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Tub PF01167.13 KEP64749.1 - 4.1e-16 58.7 0.0 1.2e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Tub family Exo_endo_phos PF03372.18 KEP64750.1 - 0.03 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TRAP_alpha PF03896.11 KEP64751.1 - 0.036 13.0 4.8 0.046 12.7 3.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SpaB_C PF14028.1 KEP64751.1 - 0.057 12.9 7.8 0.07 12.6 5.4 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain NDK PF00334.14 KEP64752.1 - 4.6e-46 155.9 0.0 1.2e-27 96.3 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Hist_deacetyl PF00850.14 KEP64754.1 - 1.9e-59 201.5 0.0 7.4e-59 199.5 0.0 1.8 1 1 0 1 1 1 1 Histone deacetylase domain Ank PF00023.25 KEP64754.1 - 6.5e-13 47.7 1.3 8.8e-06 25.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KEP64754.1 - 4.2e-12 46.2 0.0 7.2e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP64754.1 - 8e-12 45.3 3.3 3.9e-05 24.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP64754.1 - 4.1e-08 32.7 0.1 0.027 14.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KEP64754.1 - 2.2e-05 24.5 8.3 0.024 14.8 0.0 5.1 4 2 2 6 6 6 2 Ankyrin repeats (many copies) RAP PF08373.5 KEP64755.1 - 1.9e-06 27.5 1.3 5.5e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 RAP domain FAST_1 PF06743.10 KEP64755.1 - 0.11 12.2 0.6 4.6 7.0 0.0 3.3 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Herpes_gE PF02480.11 KEP64756.1 - 0.21 9.8 0.0 0.37 9.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF667 PF05018.8 KEP64758.1 - 1.5e-08 34.1 0.1 2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) WD40 PF00400.27 KEP64759.1 - 5.5e-13 48.2 5.0 0.0002 21.0 0.1 7.4 8 1 0 8 8 8 3 WD domain, G-beta repeat EGF_2 PF07974.8 KEP64760.1 - 1.9e-09 37.5 56.8 0.00041 20.4 6.7 3.6 3 0 0 3 3 3 3 EGF-like domain Kelch_4 PF13418.1 KEP64760.1 - 3.1e-09 36.4 0.0 5.3e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP64760.1 - 1e-06 28.7 0.8 7.7e-06 25.9 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KEP64760.1 - 0.00019 20.8 0.1 0.034 13.6 0.0 2.7 2 0 0 2 2 2 1 Kelch motif hEGF PF12661.2 KEP64760.1 - 0.0019 18.1 2.2 0.0019 18.1 1.5 5.4 6 0 0 6 6 6 1 Human growth factor-like EGF Kelch_2 PF07646.10 KEP64760.1 - 0.028 14.1 4.7 0.98 9.2 1.1 3.5 3 1 0 3 3 3 0 Kelch motif EB PF01683.13 KEP64760.1 - 5.1 7.2 37.6 7.4 6.7 8.2 3.6 1 1 2 3 3 3 0 EB module SieB PF14163.1 KEP64761.1 - 1.1 8.8 5.5 4.4 6.8 0.0 2.6 3 0 0 3 3 3 0 Superinfection exclusion protein B Ham1p_like PF01725.11 KEP64762.1 - 1.3e-49 168.1 0.0 1.5e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_M22 PF00814.20 KEP64763.1 - 1.5e-72 244.2 0.1 1.2e-51 175.8 0.0 3.1 2 1 1 3 3 3 3 Glycoprotease family Pro_dh PF01619.13 KEP64764.1 - 2.2e-44 151.7 0.0 3.3e-29 101.8 0.0 2.3 2 0 0 2 2 2 2 Proline dehydrogenase Ribosomal_L21p PF00829.16 KEP64765.1 - 4.6e-13 49.0 0.1 1.3e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein Methyltransf_23 PF13489.1 KEP64766.1 - 1.3e-14 54.1 0.0 6.5e-14 51.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP64766.1 - 6.8e-11 42.5 0.0 0.00025 21.4 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 KEP64766.1 - 3e-09 37.4 0.0 1.9e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KEP64766.1 - 8e-08 32.6 0.0 0.018 15.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KEP64766.1 - 9.1e-06 25.3 0.0 0.00088 18.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP64766.1 - 1.2e-05 25.6 0.0 0.023 15.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KEP64766.1 - 2.1e-05 24.5 0.0 0.0001 22.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KEP64766.1 - 0.00042 19.5 0.0 0.0025 17.0 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase NNMT_PNMT_TEMT PF01234.12 KEP64766.1 - 0.0023 16.9 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 KEP64766.1 - 0.0056 15.7 0.0 0.016 14.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEP64766.1 - 0.0085 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Nop14 PF04147.7 KEP64766.1 - 0.0086 14.0 1.2 0.011 13.7 0.8 1.1 1 0 0 1 1 1 1 Nop14-like family Myc_N PF01056.13 KEP64766.1 - 0.1 11.7 16.5 0.006 15.7 7.8 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Herpes_capsid PF06112.6 KEP64766.1 - 4 7.4 12.4 2.7 8.0 7.4 1.6 2 0 0 2 2 1 0 Gammaherpesvirus capsid protein Cpn60_TCP1 PF00118.19 KEP64767.1 - 1.9e-137 458.8 4.0 2.1e-137 458.6 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GDI PF00996.13 KEP64769.1 - 4.4e-204 677.7 0.0 5e-204 677.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor EGF_CA PF07645.10 KEP64771.1 - 1.5e-49 165.7 134.0 1.5e-09 37.6 1.5 12.6 13 0 0 13 13 13 10 Calcium-binding EGF domain cEGF PF12662.2 KEP64771.1 - 3.7e-49 163.9 87.0 1.5e-07 30.9 0.4 11.8 11 0 0 11 11 11 10 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP64771.1 - 2.3e-45 152.4 137.0 8e-12 45.0 4.6 11.5 11 1 0 11 11 11 9 Coagulation Factor Xa inhibitory site EGF PF00008.22 KEP64771.1 - 1.4e-17 63.2 121.3 0.0002 21.2 4.0 12.7 13 1 0 13 13 13 9 EGF-like domain EGF_3 PF12947.2 KEP64771.1 - 5.8e-13 48.5 108.0 0.0023 17.8 2.5 11.6 11 0 0 11 11 11 9 EGF domain DUF4483 PF14825.1 KEP64771.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) CRAL_TRIO PF00650.15 KEP64772.1 - 1.7e-20 73.1 0.0 2.6e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KEP64772.1 - 0.38 10.6 0.0 0.79 9.6 0.0 1.5 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain HAP1_N PF04849.8 KEP64775.1 - 0.0081 15.1 0.4 0.013 14.5 0.3 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Cep57_CLD_2 PF14197.1 KEP64775.1 - 0.055 13.4 3.4 0.12 12.3 2.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ADIP PF11559.3 KEP64775.1 - 0.066 13.1 1.4 0.092 12.6 1.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1904 PF08921.6 KEP64776.1 - 0.075 13.0 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) DAGK_acc PF00609.14 KEP64778.1 - 2.5e-31 109.0 0.0 4e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 KEP64778.1 - 3.2e-16 58.9 0.0 1.2e-13 50.6 0.0 2.5 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain DUF2761 PF10959.3 KEP64778.1 - 0.064 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) Herpes_BLLF1 PF05109.8 KEP64778.1 - 7.9 4.2 12.8 11 3.8 8.9 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SBDS PF01172.13 KEP64779.1 - 6.8e-28 96.3 0.1 1.2e-27 95.5 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 KEP64779.1 - 4.7e-13 48.9 0.0 1.6e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 SBDS protein C-terminal domain Hc1 PF07432.8 KEP64780.1 - 0.087 12.9 0.4 0.087 12.9 0.3 2.5 3 0 0 3 3 3 0 Histone H1-like protein Hc1 MIP-T3 PF10243.4 KEP64781.1 - 0.26 9.7 44.9 0.3 9.5 31.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CT47 PF15623.1 KEP64781.1 - 0.42 10.2 18.7 0.5 10.0 13.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Methyltransf_29 PF03141.11 KEP64781.1 - 3.1 6.0 13.8 3.8 5.7 9.6 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SprA-related PF12118.3 KEP64781.1 - 4.2 6.5 23.9 6.4 6.0 16.6 1.4 1 0 0 1 1 1 0 SprA-related family PHD PF00628.24 KEP64783.1 - 7.3e-08 31.9 1.5 2.1e-07 30.5 1.0 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KEP64783.1 - 0.064 12.5 1.3 0.16 11.3 0.9 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 KEP64783.1 - 0.4 10.4 4.0 0.98 9.2 0.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3273 PF11677.3 KEP64784.1 - 1.4e-82 276.9 9.5 1.6e-82 276.7 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF4407 PF14362.1 KEP64784.1 - 0.17 10.8 1.1 0.34 9.8 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3273 PF11677.3 KEP64785.1 - 1.2e-82 277.1 9.6 1.4e-82 276.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) UPF0233 PF06781.7 KEP64785.1 - 2.2 7.9 0.0 2.2 7.9 0.0 3.2 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0233) tRNA-synt_2 PF00152.15 KEP64787.1 - 4.3e-79 265.7 0.1 5.8e-79 265.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEP64787.1 - 8.7e-08 31.9 0.4 1.5e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEP64787.1 - 0.00097 18.3 0.3 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Gluconate_2-dh3 PF13618.1 KEP64787.1 - 0.32 11.1 4.3 19 5.3 2.9 2.6 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 RR_TM4-6 PF06459.7 KEP64787.1 - 0.55 10.0 4.2 0.97 9.2 2.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3043 PF11241.3 KEP64787.1 - 1.1 8.7 9.4 2.4 7.7 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) NARP1 PF12569.3 KEP64787.1 - 2.8 6.5 9.1 4.2 5.9 6.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PDEase_I PF00233.14 KEP64788.1 - 3.5e-56 190.6 0.3 5.6e-56 189.9 0.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KEP64788.1 - 0.00022 21.2 0.0 0.0006 19.8 0.0 1.7 1 0 0 1 1 1 1 HD domain Nop14 PF04147.7 KEP64788.1 - 1.6 6.5 29.9 2.8 5.7 20.7 1.3 1 0 0 1 1 1 0 Nop14-like family NIF PF03031.13 KEP64789.1 - 5.9e-22 78.0 0.0 1.9e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Acid_phosphat_B PF03767.9 KEP64789.1 - 1.2 8.4 0.0 2 7.7 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF1754 PF08555.5 KEP64791.1 - 2.1e-11 44.2 14.0 6.5e-11 42.7 9.7 1.7 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Ycf1 PF05758.7 KEP64791.1 - 5 4.6 9.4 5.7 4.5 6.5 1.0 1 0 0 1 1 1 0 Ycf1 Ribophorin_I PF04597.9 KEP64792.1 - 1.9e-67 227.7 0.0 6.8e-67 225.8 0.0 1.8 1 1 0 1 1 1 1 Ribophorin I SSrecog PF03531.9 KEP64792.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) AAA_2 PF07724.9 KEP64793.1 - 1.2e-41 142.4 0.7 1.4e-39 135.6 0.0 3.3 3 2 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEP64793.1 - 2.4e-23 82.7 0.0 3.2e-14 53.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEP64793.1 - 4.5e-17 62.0 0.1 6.2e-11 42.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 KEP64793.1 - 3.5e-16 58.8 0.1 6.2e-15 54.8 0.0 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KEP64793.1 - 1.5e-15 57.6 3.8 6.9e-07 29.4 0.0 5.5 3 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.21 KEP64793.1 - 5.2e-12 45.5 0.4 1e-07 31.5 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 KEP64793.1 - 3.2e-10 40.2 0.4 0.008 16.3 0.0 4.8 3 1 1 4 4 4 2 AAA domain AAA_14 PF13173.1 KEP64793.1 - 3e-07 30.4 0.0 0.099 12.5 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 KEP64793.1 - 8e-07 29.9 0.0 0.044 14.5 0.0 3.3 3 1 0 3 3 2 2 AAA domain TIP49 PF06068.8 KEP64793.1 - 3.9e-06 25.8 0.9 0.00013 20.8 0.1 2.8 3 0 0 3 3 3 1 TIP49 C-terminus IstB_IS21 PF01695.12 KEP64793.1 - 8.7e-06 25.2 0.0 0.11 11.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.7 KEP64793.1 - 9.4e-06 24.8 0.1 0.16 10.9 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEP64793.1 - 2.4e-05 23.8 0.1 0.21 10.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.6 KEP64793.1 - 3.3e-05 23.4 0.1 0.066 12.8 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEP64793.1 - 6.3e-05 22.6 0.0 0.19 11.3 0.0 3.9 3 1 0 3 3 3 1 NACHT domain AAA_18 PF13238.1 KEP64793.1 - 7.6e-05 23.0 0.1 0.48 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KEP64793.1 - 0.00012 21.8 0.0 0.04 13.6 0.0 3.6 2 1 1 3 3 3 1 Archaeal ATPase DUF815 PF05673.8 KEP64793.1 - 0.00042 19.3 0.1 0.84 8.5 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KEP64793.1 - 0.00079 19.5 0.0 2.1 8.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 KEP64793.1 - 0.00083 18.5 0.0 0.12 11.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 KEP64793.1 - 0.00098 18.1 0.2 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 KEP64793.1 - 0.0011 18.3 0.5 1.5 8.4 0.0 3.3 4 0 0 4 4 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KEP64793.1 - 0.0015 17.7 0.1 0.96 8.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KEP64793.1 - 0.0026 17.6 0.0 3.3 7.6 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Mg_chelatase PF01078.16 KEP64793.1 - 0.0037 16.4 1.4 3.2 6.8 0.2 3.3 2 2 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEP64793.1 - 0.0049 16.8 0.2 6.8 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.4 KEP64793.1 - 0.006 15.2 0.0 0.63 8.5 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 KEP64793.1 - 0.0077 15.9 0.1 1 9.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain DUF87 PF01935.12 KEP64793.1 - 0.0095 15.7 0.1 0.34 10.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_21 PF13304.1 KEP64793.1 - 0.01 15.8 0.3 0.91 9.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KEP64793.1 - 0.012 15.8 0.1 0.93 9.7 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 KEP64793.1 - 0.02 15.2 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEP64793.1 - 0.025 14.0 0.1 11 5.3 0.0 3.8 3 1 1 4 4 4 0 AAA-like domain ResIII PF04851.10 KEP64793.1 - 0.027 14.2 0.0 5.2 6.8 0.0 3.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 KEP64793.1 - 0.036 13.9 0.6 17 5.3 0.0 3.4 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.1 KEP64793.1 - 0.042 13.4 0.1 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.1 KEP64793.1 - 0.069 12.8 0.0 2 8.0 0.0 2.7 2 1 0 2 2 2 0 DNA polymerase III, delta subunit UPF0079 PF02367.12 KEP64793.1 - 0.081 12.5 0.1 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KEP64793.1 - 0.14 12.6 0.0 7.1 7.1 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein Leu_Phe_trans PF03588.9 KEP64794.1 - 1.3e-22 79.7 0.1 7.7e-13 47.9 0.0 3.0 3 0 0 3 3 3 2 Leucyl/phenylalanyl-tRNA protein transferase PP2C PF00481.16 KEP64796.1 - 4.9e-39 134.2 0.0 6e-32 111.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KEP64796.1 - 4.9e-05 22.8 0.0 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C HemY_N PF07219.8 KEP64797.1 - 0.27 10.7 0.1 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 HemY protein N-terminus Peptidase_M41 PF01434.13 KEP64798.1 - 2.7e-58 196.9 0.0 4.1e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEP64798.1 - 1.1e-40 138.8 0.0 2.3e-40 137.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEP64798.1 - 4e-05 24.4 0.0 0.00012 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsH_ext PF06480.10 KEP64798.1 - 0.00028 21.0 0.0 0.0019 18.3 0.0 2.3 1 1 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KEP64798.1 - 0.00033 20.4 0.1 0.0011 18.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KEP64798.1 - 0.00035 19.4 0.0 0.00062 18.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 KEP64798.1 - 0.00042 20.4 0.2 0.036 14.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP64798.1 - 0.0018 18.0 0.3 0.011 15.5 0.2 2.4 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KEP64798.1 - 0.0048 15.9 0.0 0.0099 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KEP64798.1 - 0.016 14.6 0.5 0.036 13.5 0.4 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 KEP64798.1 - 0.021 14.6 0.1 0.055 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KEP64798.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEP64798.1 - 0.029 14.3 0.1 0.029 14.3 0.1 2.4 3 1 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.1 KEP64798.1 - 0.032 14.1 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEP64798.1 - 0.042 13.2 1.0 0.11 11.8 0.5 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEP64798.1 - 0.05 12.7 0.2 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEP64798.1 - 0.054 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEP64798.1 - 0.064 12.3 0.1 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KEP64798.1 - 0.064 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain TT_ORF2 PF02957.10 KEP64798.1 - 2.9 8.6 7.2 0.49 11.0 0.8 2.5 2 0 0 2 2 2 0 TT viral ORF2 PseudoU_synth_2 PF00849.17 KEP64799.1 - 7.5e-13 48.6 0.0 2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3402 PF11882.3 KEP64799.1 - 2 7.4 0.0 3.4 6.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) TMEM51 PF15345.1 KEP64800.1 - 2.1 8.0 6.4 3.1 7.4 4.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 GCC2_GCC3 PF07699.8 KEP64801.1 - 1.3e-06 27.8 12.5 2e-06 27.2 0.6 3.4 3 0 0 3 3 3 2 GCC2 and GCC3 Peptidase_M16_C PF05193.16 KEP64802.1 - 1.2e-36 126.0 0.0 3.5e-36 124.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEP64802.1 - 2e-24 86.0 0.0 5.7e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RNA_POL_M_15KD PF02150.11 KEP64803.1 - 4.6e-12 45.4 4.9 4.6e-12 45.4 3.4 1.8 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 KEP64803.1 - 1.2e-05 24.8 5.0 1.4e-05 24.6 0.1 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 KEP64803.1 - 0.0068 16.2 1.2 0.0068 16.2 0.8 2.3 3 0 0 3 3 3 1 Double zinc ribbon IBR PF01485.16 KEP64803.1 - 0.057 13.3 3.6 1.1 9.1 0.8 2.8 3 0 0 3 3 3 0 IBR domain Zn_ribbon_recom PF13408.1 KEP64803.1 - 0.099 12.9 1.2 0.39 10.9 0.2 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain GFA PF04828.9 KEP64803.1 - 0.17 11.8 2.5 8.4 6.4 0.7 2.7 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme PHD PF00628.24 KEP64803.1 - 0.19 11.4 7.1 9.2 6.0 2.4 3.3 3 1 0 3 3 3 0 PHD-finger zf-ribbon_3 PF13248.1 KEP64803.1 - 0.3 10.3 4.2 2.5 7.4 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 KEP64803.1 - 0.34 10.9 3.0 7.3 6.6 0.7 2.7 2 0 0 2 2 2 0 zinc-finger zf-3CxxC PF13695.1 KEP64803.1 - 0.59 10.3 4.9 2.6 8.3 2.8 2.3 1 1 1 2 2 2 0 Zinc-binding domain DUF2387 PF09526.5 KEP64803.1 - 0.78 9.6 6.2 0.74 9.7 0.5 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Rubredoxin PF00301.15 KEP64803.1 - 0.86 9.5 15.3 1 9.2 0.1 3.8 3 1 1 4 4 4 0 Rubredoxin zf-TFIIB PF13453.1 KEP64803.1 - 3.4 6.9 6.2 5.7 6.2 0.2 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger Ogr_Delta PF04606.7 KEP64803.1 - 5.7 6.6 5.8 18 5.0 1.3 3.0 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger DUF2296 PF10058.4 KEP64803.1 - 6 6.7 9.8 3 7.6 0.5 3.1 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zinc_ribbon_2 PF13240.1 KEP64803.1 - 7.4 6.2 6.9 69 3.1 2.3 3.4 3 1 0 3 3 3 0 zinc-ribbon domain RNB PF00773.14 KEP64805.1 - 1.2e-60 205.5 0.0 3.6e-46 157.9 0.0 3.2 2 1 0 2 2 2 2 RNB domain VIT1 PF01988.14 KEP64806.1 - 0.041 13.3 4.6 0.098 12.1 3.2 1.5 1 0 0 1 1 1 0 VIT family RNase_PH PF01138.16 KEP64808.1 - 2.4e-12 47.2 0.0 4.9e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEP64808.1 - 0.00035 20.4 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRM_1 PF00076.17 KEP64810.1 - 7.4e-49 163.2 0.1 2.4e-19 68.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64810.1 - 3.3e-35 119.8 0.0 3.3e-13 49.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64810.1 - 3.3e-33 113.3 0.1 3.4e-11 42.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEP64810.1 - 0.00066 19.3 0.0 0.08 12.7 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Glyoxalase_5 PF14696.1 KEP64810.1 - 0.024 14.5 0.1 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal RRM_3 PF08777.6 KEP64810.1 - 0.11 12.3 1.0 2.1 8.2 0.0 3.2 4 0 0 4 4 4 0 RNA binding motif DUF533 PF04391.7 KEP64810.1 - 0.25 10.6 10.7 1.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Pkinase PF00069.20 KEP64811.1 - 3.1e-18 65.8 0.0 1e-17 64.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 KEP64811.1 - 5.6e-14 51.7 0.0 8.8e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KEP64811.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Ribosomal_L6e_N PF03868.10 KEP64811.1 - 0.072 12.9 0.2 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L6, N-terminal domain Dus PF01207.12 KEP64812.1 - 4.5e-63 212.9 0.0 9.4e-52 175.7 0.0 3.1 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) PEP_mutase PF13714.1 KEP64812.1 - 0.028 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DHO_dh PF01180.16 KEP64812.1 - 0.039 12.9 0.0 0.28 10.1 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase ThiG PF05690.9 KEP64812.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.7 KEP64812.1 - 0.076 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.20 KEP64812.1 - 0.23 10.3 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain CtaG_Cox11 PF04442.9 KEP64813.1 - 2.2e-49 167.1 0.0 3.2e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ PF00226.26 KEP64814.1 - 8.8e-08 31.7 0.1 1.2e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KEP64814.1 - 1.1e-06 28.4 0.8 1.7e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Pam16 UQ_con PF00179.21 KEP64815.1 - 2.6e-44 150.0 0.0 3.1e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme C2 PF00168.25 KEP64816.1 - 2.2e-14 53.0 0.2 3.2e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 C2 domain FHA PF00498.21 KEP64817.1 - 3.6e-13 49.4 0.2 6.1e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 FHA domain RINGv PF12906.2 KEP64817.1 - 4.2e-13 49.1 6.4 7.4e-13 48.3 4.4 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KEP64817.1 - 0.037 13.9 3.2 0.069 13.1 2.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Siah-Interact_N PF09032.6 KEP64817.1 - 0.13 12.3 3.5 0.47 10.5 2.4 1.9 1 0 0 1 1 1 0 Siah interacting protein, N terminal zf-RING_2 PF13639.1 KEP64817.1 - 0.61 9.9 5.3 1.1 9.1 3.7 1.4 1 0 0 1 1 1 0 Ring finger domain ATP_bind_4 PF01902.12 KEP64818.1 - 4.9e-33 114.3 0.0 9.2e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 ATP-binding region Serendipity_A PF05482.7 KEP64818.1 - 0.87 7.9 0.9 1.5 7.1 0.6 1.2 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Paramyxo_PNT PF13825.1 KEP64819.1 - 0.15 11.2 4.8 0.16 11.1 3.3 1.0 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus RtcB PF01139.12 KEP64819.1 - 0.47 9.3 5.1 0.52 9.2 3.5 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB Activator_LAG-3 PF11498.3 KEP64819.1 - 0.79 8.4 6.5 0.93 8.1 4.5 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Mnd1 PF03962.10 KEP64819.1 - 0.94 9.1 9.2 0.95 9.0 6.4 1.1 1 0 0 1 1 1 0 Mnd1 family PGA2 PF07543.7 KEP64819.1 - 3.9 7.2 13.3 4.7 7.0 9.2 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 SAP PF02037.22 KEP64820.1 - 1e-15 56.7 0.3 4.4e-15 54.7 0.2 2.2 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 KEP64820.1 - 0.11 12.0 0.1 0.25 10.9 0.0 1.6 1 1 0 1 1 1 0 HeH/LEM domain Mito_carr PF00153.22 KEP64821.1 - 6.1e-37 125.2 0.1 2.6e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein ELM2 PF01448.19 KEP64822.1 - 0.06 13.9 0.3 0.22 12.2 0.0 2.0 2 0 0 2 2 2 0 ELM2 domain zf-CCCH PF00642.19 KEP64823.1 - 0.00018 21.0 1.9 0.00018 21.0 1.3 3.4 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Zn_ribbon_recom PF13408.1 KEP64823.1 - 0.26 11.5 4.9 0.082 13.1 0.5 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Peptidase_M14 PF00246.19 KEP64824.1 - 1.2e-27 97.2 0.0 1.5e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 KEP64824.1 - 0.0007 18.7 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) SAP PF02037.22 KEP64824.1 - 0.091 12.2 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 SAP domain Chorismate_bind PF00425.13 KEP64825.1 - 6.5e-83 277.9 0.0 9.8e-83 277.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 KEP64825.1 - 2.1e-42 144.7 0.0 3.2e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KEP64825.1 - 6.1e-09 36.0 0.0 1.4e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KEP64825.1 - 8.1e-07 28.7 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DZR PF12773.2 KEP64826.1 - 0.5 10.2 5.0 1.4 8.7 1.5 2.7 3 0 0 3 3 3 0 Double zinc ribbon GCV_H PF01597.14 KEP64829.1 - 3e-24 85.0 4.1 4e-20 71.7 0.3 3.0 2 1 1 3 3 3 2 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KEP64829.1 - 0.00016 21.2 0.3 0.0003 20.3 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 KEP64829.1 - 0.095 12.4 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF1192 PF06698.6 KEP64830.1 - 0.08 12.7 5.1 0.49 10.2 0.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Prp19 PF08606.6 KEP64830.1 - 1.9 8.2 12.3 1.3 8.7 0.4 3.4 2 1 1 3 3 3 0 Prp19/Pso4-like ARD PF03079.9 KEP64830.1 - 5.6 6.8 10.2 1 9.2 3.8 2.1 1 1 1 2 2 2 0 ARD/ARD' family Fib_alpha PF08702.5 KEP64830.1 - 7.1 6.7 26.1 0.042 13.9 8.9 3.2 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 KEP64830.1 - 7.2 4.3 31.7 1.3e+03 -3.2 22.0 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family NUC173 PF08161.7 KEP64832.1 - 7.8e-14 51.4 2.5 1.9e-13 50.2 0.1 2.7 3 0 0 3 3 3 1 NUC173 domain DUF2435 PF10363.4 KEP64832.1 - 0.013 15.3 0.2 0.071 13.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Pkinase PF00069.20 KEP64835.1 - 7.2e-62 208.8 0.0 1.1e-61 208.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64835.1 - 9.7e-34 116.6 0.0 1.6e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MMR_HSR1 PF01926.18 KEP64836.1 - 4.6e-37 126.5 0.0 1.6e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 KEP64836.1 - 1.2e-25 89.3 0.1 3.7e-25 87.6 0.1 2.0 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 KEP64836.1 - 1.5e-15 56.8 0.1 4.9e-08 32.4 0.0 4.1 3 1 0 3 3 3 2 Ferrous iron transport protein B Miro PF08477.8 KEP64836.1 - 1.4e-12 48.1 0.0 3.9e-05 24.1 0.0 3.6 3 0 0 3 3 3 2 Miro-like protein GTP_EFTU PF00009.22 KEP64836.1 - 3.2e-12 46.2 0.0 0.002 17.5 0.0 5.4 5 1 0 5 5 5 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEP64836.1 - 4.5e-07 29.8 1.6 0.0079 16.0 0.0 3.9 3 1 1 4 4 4 1 Dynamin family DUF258 PF03193.11 KEP64836.1 - 6.9e-07 28.5 0.0 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AIG1 PF04548.11 KEP64836.1 - 2.5e-05 23.4 0.0 0.079 12.0 0.0 2.4 2 0 0 2 2 2 2 AIG1 family Ras PF00071.17 KEP64836.1 - 5.1e-05 22.7 0.0 0.45 9.8 0.0 3.4 3 1 0 3 3 3 2 Ras family AAA_22 PF13401.1 KEP64836.1 - 0.00055 20.0 0.0 0.94 9.6 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KEP64836.1 - 0.00097 19.4 0.1 1.2 9.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 KEP64836.1 - 0.0029 17.3 0.1 0.74 9.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KEP64836.1 - 0.0052 17.0 0.0 0.87 9.8 0.0 2.4 2 0 0 2 2 2 1 ABC transporter SRPRB PF09439.5 KEP64836.1 - 0.0055 15.9 0.0 0.33 10.1 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 KEP64836.1 - 0.0068 15.8 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KEP64836.1 - 0.007 17.1 0.0 0.51 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEP64836.1 - 0.0077 16.3 0.0 5.3 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Gtr1_RagA PF04670.7 KEP64836.1 - 0.01 14.9 0.0 0.92 8.6 0.0 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Septin PF00735.13 KEP64836.1 - 0.014 14.3 0.0 0.89 8.5 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_33 PF13671.1 KEP64836.1 - 0.027 14.3 0.1 4.4 7.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 KEP64836.1 - 0.032 13.9 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 KEP64836.1 - 0.037 13.7 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.1 KEP64836.1 - 0.044 13.3 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.1 KEP64836.1 - 0.051 13.5 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KEP64836.1 - 0.074 11.8 0.0 5.3 5.7 0.0 2.7 2 0 0 2 2 2 0 ArgK protein AAA_14 PF13173.1 KEP64836.1 - 0.082 12.8 0.0 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEP64836.1 - 0.11 11.9 0.1 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain GBP PF02263.14 KEP64836.1 - 0.19 10.7 0.1 5.3 6.0 0.0 2.4 2 1 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Bax1-I PF01027.15 KEP64838.1 - 2.4e-30 105.6 30.9 2.9e-30 105.3 21.4 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 KEP64838.1 - 0.17 10.7 0.0 0.53 9.2 0.0 1.8 1 0 0 1 1 1 0 Orbivirus NS3 ACDC PF14733.1 KEP64840.1 - 9.5e-13 48.0 0.5 2e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.15 KEP64840.1 - 1e-12 47.9 0.4 5.1e-06 26.5 0.4 2.8 2 0 0 2 2 2 2 AP2 domain SpoU_methylase PF00588.14 KEP64841.1 - 1.1e-07 31.7 0.0 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family MARVEL PF01284.18 KEP64842.1 - 0.00056 19.7 1.1 0.023 14.5 0.1 2.1 2 0 0 2 2 2 2 Membrane-associating domain RRM_1 PF00076.17 KEP64843.1 - 1.6e-17 62.8 0.1 2.7e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64843.1 - 1.9e-13 50.2 0.1 3.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64843.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.16 KEP64846.1 - 1.8e-121 405.2 0.0 2.1e-121 404.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase SIP1 PF04938.7 KEP64847.1 - 6.5e-08 32.2 6.2 0.00024 20.5 2.2 3.2 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) Dynein_heavy PF03028.10 KEP64848.1 - 2.7e-242 805.8 0.0 6.2e-242 804.6 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 KEP64848.1 - 8.3e-145 483.4 8.4 8.3e-145 483.4 5.8 3.4 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 KEP64848.1 - 1.4e-119 397.7 0.2 6.1e-119 395.6 0.1 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 KEP64848.1 - 7.3e-107 357.3 6.8 7.3e-107 357.3 4.7 4.9 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.2 KEP64848.1 - 1.2e-93 313.0 0.0 2.9e-93 311.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KEP64848.1 - 9.2e-84 279.8 1.0 2e-83 278.6 0.7 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 KEP64848.1 - 1.1e-73 247.7 0.2 1.9e-73 246.8 0.2 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 KEP64848.1 - 2.3e-64 217.3 13.9 4.4e-64 216.4 9.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEP64848.1 - 1.2e-31 109.2 0.0 7e-10 38.7 0.0 6.3 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 KEP64848.1 - 1.9e-07 31.3 0.1 0.074 13.2 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP64848.1 - 2.8e-06 27.4 0.7 0.0039 17.3 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA_17 PF13207.1 KEP64848.1 - 3.4e-06 27.8 0.4 0.31 11.8 0.0 5.9 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 KEP64848.1 - 3.6e-05 23.8 15.6 0.13 12.2 0.0 7.6 7 1 1 8 8 7 2 AAA ATPase domain AAA_33 PF13671.1 KEP64848.1 - 0.00083 19.2 0.0 0.08 12.8 0.0 4.1 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.16 KEP64848.1 - 0.00097 18.3 0.8 0.74 8.9 0.0 3.9 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KEP64848.1 - 0.001 18.9 0.4 0.11 12.3 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 KEP64848.1 - 0.0012 19.1 0.3 5.5 7.3 0.0 4.5 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 KEP64848.1 - 0.0018 18.4 0.0 30 4.8 0.0 4.2 4 0 0 4 4 3 0 RNA helicase AAA_29 PF13555.1 KEP64848.1 - 0.008 15.6 0.1 0.68 9.5 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KEP64848.1 - 0.0095 15.6 1.2 2.9 7.6 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain ABC_tran PF00005.22 KEP64848.1 - 0.011 16.0 0.0 1.4 9.1 0.0 4.0 3 0 0 3 3 3 0 ABC transporter Rep_fac-A_C PF08646.5 KEP64851.1 - 1.9e-29 102.2 0.7 7.2e-29 100.3 0.3 2.0 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 KEP64851.1 - 9.3e-08 31.8 1.5 1.4e-06 28.0 0.1 3.0 3 1 0 3 3 3 1 OB-fold nucleic acid binding domain POT1 PF02765.12 KEP64851.1 - 0.033 14.0 0.0 0.42 10.5 0.0 2.6 3 0 0 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 GTP-bdg_N PF13167.1 KEP64851.1 - 0.14 12.2 0.4 2.2 8.4 0.0 2.7 2 1 1 3 3 3 0 GTP-binding GTPase N-terminal Ank_4 PF13637.1 KEP64852.1 - 3.6e-19 68.7 6.4 8.5e-05 22.9 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEP64852.1 - 4.6e-19 68.5 3.9 3.2e-05 24.1 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEP64852.1 - 2.7e-14 52.1 20.1 3.2e-06 26.6 0.1 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 KEP64852.1 - 6.9e-11 42.0 18.1 0.0073 16.5 0.1 6.4 6 0 0 6 6 6 3 Ankyrin repeats (many copies) LRR_4 PF12799.2 KEP64852.1 - 2.9e-07 29.9 14.8 9.1e-07 28.3 0.7 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Ank_3 PF13606.1 KEP64852.1 - 3.7e-06 26.6 9.0 0.01 15.9 0.0 6.4 8 0 0 8 8 8 2 Ankyrin repeat LRR_8 PF13855.1 KEP64852.1 - 1e-05 25.1 8.7 0.00012 21.7 1.1 3.8 2 2 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KEP64852.1 - 0.0016 18.2 8.7 0.35 11.0 0.3 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KEP64852.1 - 0.02 14.9 7.6 5.1 7.7 0.1 4.7 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KEP64853.1 - 5.8e-06 25.8 2.3 1.3 9.3 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 KEP64853.1 - 1.9e-05 24.1 3.0 0.0043 16.6 1.3 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEP64853.1 - 0.011 15.5 6.4 5.5 7.4 0.0 3.7 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.1 KEP64853.1 - 0.045 13.5 3.9 1.6 8.5 2.4 2.8 2 0 0 2 2 2 0 Leucine rich repeat DUF1796 PF08795.5 KEP64853.1 - 0.081 12.5 0.1 0.34 10.5 0.1 1.9 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) DEAD PF00270.24 KEP64854.1 - 2.2e-37 128.1 0.0 4e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP64854.1 - 2.2e-15 56.2 0.0 4.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2407_C PF13373.1 KEP64857.1 - 0.26 11.1 0.9 0.81 9.6 0.6 1.9 1 0 0 1 1 1 0 DUF2407 C-terminal domain Rad17 PF03215.10 KEP64858.1 - 6.2e-10 38.3 0.0 0.002 16.9 0.0 5.2 4 1 0 4 4 4 4 Rad17 cell cycle checkpoint protein AA_permease_N PF08403.5 KEP64859.1 - 0.04 13.2 0.2 0.04 13.2 0.1 2.4 2 1 0 2 2 2 0 Amino acid permease N-terminal GAGA_bind PF06217.7 KEP64859.1 - 0.36 10.7 18.6 0.48 10.3 12.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TATR PF03430.8 KEP64859.1 - 0.44 9.1 18.5 0.52 8.8 12.8 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF572 PF04502.8 KEP64859.1 - 0.77 8.9 30.7 0.94 8.6 21.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) FLO_LFY PF01698.11 KEP64859.1 - 2.3 6.9 20.0 3.2 6.5 13.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein SR-25 PF10500.4 KEP64859.1 - 3.2 7.1 52.2 2.6 7.4 35.1 1.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Nucleo_P87 PF07267.6 KEP64859.1 - 4 6.0 23.2 3 6.4 15.3 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4661 PF15576.1 KEP64859.1 - 8.4 5.9 22.1 4.1 6.9 14.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) DUF3827 PF12877.2 KEP64859.1 - 9 4.2 18.9 11 3.9 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF726 PF05277.7 KEP64861.1 - 1.1e-104 350.0 0.2 1.5e-104 349.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KEP64861.1 - 0.013 15.2 0.6 0.06 13.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family LCAT PF02450.10 KEP64861.1 - 0.04 12.8 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase VirJ PF06057.6 KEP64861.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3842 PF12953.2 KEP64862.1 - 0.0038 17.3 0.0 0.0066 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3842) DUF3611 PF12263.3 KEP64862.1 - 0.038 13.3 0.7 0.89 8.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) zf-UBR PF02207.15 KEP64863.1 - 5.9e-17 61.1 14.4 2.2e-16 59.2 10.0 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Potyvirid-P3 PF13608.1 KEP64863.1 - 2.1 7.3 4.1 3.9 6.4 2.9 1.3 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein SRR PF07709.6 KEP64863.1 - 3.3 8.2 0.0 7.6 7.1 0.0 1.6 1 0 0 1 1 1 0 Seven Residue Repeat DUF4509 PF14970.1 KEP64864.1 - 0.031 13.9 0.6 0.031 13.9 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4509) DUF812 PF05667.6 KEP64864.1 - 0.16 10.4 26.5 0.04 12.4 13.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.7 KEP64864.1 - 0.63 9.8 11.2 5 6.9 0.7 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.6 KEP64864.1 - 0.66 9.7 39.7 1.8 8.3 0.7 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 KEP64864.1 - 1.1 8.3 9.9 0.63 9.1 3.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KEP64864.1 - 1.4 8.6 39.2 0.043 13.5 14.3 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FTO_CTD PF12934.2 KEP64864.1 - 1.7 8.2 9.5 0.16 11.4 1.8 2.3 2 1 0 2 2 2 0 FTO C-terminal domain Laminin_II PF06009.7 KEP64864.1 - 3.7 7.3 25.2 0.66 9.7 4.8 3.1 2 1 1 3 3 3 0 Laminin Domain II Transposase_22 PF02994.9 KEP64864.1 - 4.3 5.7 21.5 0.76 8.2 11.4 1.9 2 0 0 2 2 2 0 L1 transposable element IncA PF04156.9 KEP64864.1 - 6.9 6.2 42.3 0.26 10.8 12.0 3.2 2 1 1 3 3 3 0 IncA protein Alkyl_sulf_dimr PF14863.1 KEP64865.1 - 2.4e-39 134.7 0.2 4.3e-39 133.9 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 KEP64865.1 - 2.2e-16 60.1 0.0 6e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.1 KEP64865.1 - 1.1e-08 35.1 0.0 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2 PF02036.12 KEP64865.1 - 2.1e-07 31.1 0.0 1.5e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 SCP-2 sterol transfer family Lactamase_B_2 PF12706.2 KEP64865.1 - 0.006 16.1 0.1 0.014 14.9 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Mg_trans_NIPA PF05653.9 KEP64866.1 - 1.6e-18 66.6 13.9 2.4e-18 66.1 9.6 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KEP64866.1 - 0.0015 18.5 26.2 0.0027 17.7 3.3 3.2 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KEP64866.1 - 0.0038 17.4 6.4 0.0038 17.4 4.5 2.7 2 1 0 2 2 2 1 Multidrug resistance efflux transporter LPAM_1 PF08139.7 KEP64866.1 - 3 8.1 5.6 4.8 7.5 0.1 3.6 3 0 0 3 3 3 0 Prokaryotic membrane lipoprotein lipid attachment site Prefoldin PF02996.12 KEP64868.1 - 1.1e-12 47.6 5.3 2.2e-12 46.6 0.2 2.3 2 1 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 KEP64868.1 - 0.16 11.7 0.1 0.16 11.7 0.0 2.8 2 1 1 3 3 3 0 Prefoldin subunit Utp12 PF04003.7 KEP64869.1 - 5.4e-06 26.2 2.5 8.5e-06 25.6 1.7 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Secretin_N PF03958.12 KEP64869.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.6 3 1 0 3 3 3 0 Bacterial type II/III secretion system short domain CPW_WPC PF09717.5 KEP64870.1 - 2.5e-64 213.7 37.2 1.1e-18 67.6 5.8 4.2 4 0 0 4 4 4 4 Plasmodium falciparum domain of unknown function (CPW_WPC) DnaJ PF00226.26 KEP64871.1 - 3.4e-18 65.1 2.0 4.9e-17 61.4 0.4 3.4 2 1 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.26 KEP64871.1 - 7.2e-17 61.1 0.3 4.5e-07 29.8 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEP64871.1 - 1.2e-08 34.8 5.6 0.0011 19.0 0.0 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain CRAL_TRIO PF00650.15 KEP64872.1 - 1.1e-26 93.2 0.0 1.5e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEP64872.1 - 0.001 19.1 0.1 0.0038 17.3 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KEP64872.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain K_channel_TID PF07941.6 KEP64872.1 - 0.053 13.7 9.5 0.15 12.3 0.3 2.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain L27_2 PF09045.5 KEP64872.1 - 4.2 6.9 6.1 12 5.5 0.1 2.5 2 0 0 2 2 2 0 L27_2 RskA PF10099.4 KEP64873.1 - 0.0044 16.7 0.7 0.016 14.9 0.3 1.9 2 0 0 2 2 2 1 Anti-sigma-K factor rskA UPF0054 PF02130.12 KEP64874.1 - 2.6e-21 75.4 0.0 8.1e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0054 ACPS PF01648.15 KEP64874.1 - 3.9e-10 39.5 0.0 2.4e-09 37.0 0.0 2.4 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily APC10 PF03256.11 KEP64875.1 - 2.5e-34 118.5 0.0 6.7e-34 117.1 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF3228 PF11539.3 KEP64876.1 - 4.4e-69 231.5 0.0 5.5e-69 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) UPF0203 PF05254.7 KEP64877.1 - 3e-16 59.0 1.5 4.2e-16 58.5 1.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 KEP64877.1 - 0.084 12.8 1.7 0.83 9.6 0.2 2.2 2 0 0 2 2 2 0 CHCH domain COX17 PF05051.8 KEP64877.1 - 0.18 11.8 0.7 0.68 10.0 0.5 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Kelch_5 PF13854.1 KEP64878.1 - 2.8e-09 36.7 0.3 7.8e-06 25.7 0.1 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 KEP64878.1 - 6e-07 29.1 1.1 7e-05 22.5 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP64878.1 - 8.6e-05 22.5 20.0 2.1 8.6 0.0 8.0 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KEP64878.1 - 0.0054 16.8 0.0 1.3 9.3 0.0 3.1 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 KEP64878.1 - 0.02 14.4 0.0 3.4 7.3 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 KEP64878.1 - 0.036 13.8 0.1 14 5.6 0.0 3.3 3 0 0 3 3 3 0 Kelch motif GN3L_Grn1 PF08701.6 KEP64879.1 - 2.8e-21 75.1 11.0 2.8e-21 75.1 7.6 3.0 3 0 0 3 3 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KEP64879.1 - 6.4e-19 68.0 0.0 1.3e-14 54.1 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP64879.1 - 7.8e-10 38.2 0.0 3.1e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEP64879.1 - 0.00013 21.4 0.5 0.48 9.8 0.0 3.5 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEP64879.1 - 0.00013 21.7 0.8 1.3 8.8 0.1 3.7 3 0 0 3 3 3 2 Dynamin family Miro PF08477.8 KEP64879.1 - 0.0032 17.9 0.0 0.28 11.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 KEP64879.1 - 0.0054 15.9 0.0 0.014 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 KEP64879.1 - 0.021 14.0 0.3 0.055 12.6 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit cobW PF02492.14 KEP64879.1 - 0.066 12.6 0.2 4.7 6.6 0.0 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KEP64879.1 - 0.071 11.8 0.8 0.19 10.5 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 KEP64879.1 - 5.1 7.0 12.8 0.46 10.4 0.1 3.3 3 2 0 3 3 3 0 AAA ATPase domain AlaDh_PNT_N PF05222.10 KEP64880.1 - 2.1e-40 137.8 0.6 9.2e-40 135.7 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KEP64880.1 - 4.1e-26 91.5 10.8 6.1e-24 84.4 4.1 2.9 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KEP64880.1 - 0.00057 19.9 0.2 0.0019 18.2 0.2 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 KEP64880.1 - 0.0021 17.9 0.2 0.0047 16.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KEP64880.1 - 0.005 17.0 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 KEP64880.1 - 0.023 15.0 0.2 0.068 13.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEP64880.1 - 0.18 10.5 3.2 0.39 9.5 2.2 1.5 1 0 0 1 1 1 0 FAD binding domain zf-RING_2 PF13639.1 KEP64882.1 - 4e-09 36.1 14.9 6.1e-09 35.5 8.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEP64882.1 - 8.4e-06 25.7 18.7 1.1e-05 25.3 9.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP64882.1 - 1.4e-05 24.5 12.2 1.4e-05 24.5 8.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP64882.1 - 4e-05 23.1 12.7 4e-05 23.1 8.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LON PF02190.11 KEP64882.1 - 0.00024 20.8 0.0 0.00087 19.0 0.0 1.8 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain zf-RING_5 PF14634.1 KEP64882.1 - 0.00053 19.6 14.1 0.00053 19.6 9.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEP64882.1 - 0.0086 15.9 16.8 0.0086 15.9 11.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KEP64882.1 - 0.092 12.3 8.5 0.22 11.1 5.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.10 KEP64882.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.2 KEP64882.1 - 6.6 6.9 12.3 0.64 10.1 4.8 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger cNMP_binding PF00027.24 KEP64883.1 - 0.00058 19.6 0.0 0.0073 16.1 0.0 2.3 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RRM_1 PF00076.17 KEP64884.1 - 3.1e-51 170.8 0.0 5.5e-17 61.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP64884.1 - 6.4e-37 125.3 0.2 9.7e-13 47.9 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP64884.1 - 2.8e-30 103.9 0.2 4.6e-09 35.9 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 KEP64884.1 - 0.018 14.5 0.0 0.054 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Limkain-b1 PF11608.3 KEP64884.1 - 0.71 9.6 5.1 3.4 7.4 0.0 4.1 5 0 0 5 5 5 0 Limkain b1 NAD_binding_4 PF07993.7 KEP64885.1 - 1.8e-59 200.6 0.0 2.7e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.16 KEP64885.1 - 2.4e-16 59.3 0.0 4.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Epimerase PF01370.16 KEP64885.1 - 4.9e-10 39.2 0.0 1.6e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEP64885.1 - 5.9e-09 35.0 0.0 7.2e-07 28.1 0.1 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sterile PF03015.14 KEP64885.1 - 0.00074 19.7 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KEP64885.1 - 0.052 12.4 0.2 0.87 8.4 0.1 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KEP64885.1 - 0.11 12.7 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain EXOSC1 PF10447.4 KEP64888.1 - 5.4e-25 87.1 0.1 9.6e-25 86.3 0.1 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KEP64888.1 - 5.6e-14 51.1 0.1 1.2e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region MRP-S28 PF10213.4 KEP64889.1 - 4.9e-11 42.8 0.0 1.6e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein ERF PF04404.7 KEP64889.1 - 0.056 12.9 0.2 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 ERF superfamily Ribosomal_L44 PF00935.14 KEP64890.1 - 7.7e-34 115.5 12.0 9.9e-34 115.1 8.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 Chorein_N PF12624.2 KEP64891.1 - 1.4e-16 60.1 0.0 2.6e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter AP2 PF00847.15 KEP64895.1 - 6.1e-07 29.4 2.0 7.3e-07 29.2 0.7 1.7 2 0 0 2 2 2 1 AP2 domain Got1 PF04178.7 KEP64896.1 - 4.4e-24 84.8 8.4 6.1e-24 84.3 5.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AP2 PF00847.15 KEP64897.1 - 6e-06 26.3 6.6 0.0001 22.3 0.3 2.8 3 0 0 3 3 3 2 AP2 domain ACDC PF14733.1 KEP64897.1 - 0.85 9.7 0.0 1.9 8.6 0.0 1.6 1 0 0 1 1 1 0 AP2-coincident C-terminal VKOR PF07884.9 KEP64898.1 - 7.5e-14 51.7 9.4 9.3e-14 51.4 6.5 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family RAP PF08373.5 KEP64899.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 RAP domain NatB_MDM20 PF09797.4 KEP64901.1 - 1.1e-05 24.3 0.0 3.2e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit eIF-3c_N PF05470.7 KEP64901.1 - 0.087 10.8 0.0 0.14 10.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PMP1_2 PF08114.6 KEP64904.1 - 0.065 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 ATPase proteolipid family DUF4448 PF14610.1 KEP64904.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF461 PF04314.8 KEP64906.1 - 0.049 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF461) Rrn6 PF10214.4 KEP64906.1 - 0.098 10.7 1.2 0.13 10.3 0.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor OHA PF14418.1 KEP64907.1 - 1.4e-16 59.7 0.0 8.8e-10 37.9 0.0 2.6 2 0 0 2 2 2 2 OST-HTH Associated domain Kelch_3 PF13415.1 KEP64908.1 - 1.7e-29 101.2 9.6 9.1e-07 28.8 0.4 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KEP64908.1 - 3.4e-26 90.7 6.5 8e-05 22.4 0.1 5.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 KEP64908.1 - 4.3e-26 90.4 17.2 4.2e-06 26.4 0.0 5.6 4 2 1 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KEP64908.1 - 1.1e-20 72.9 10.6 5.5e-05 23.1 0.0 5.8 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KEP64908.1 - 7.4e-18 63.8 12.4 2.9e-05 23.5 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KEP64908.1 - 3e-13 48.9 13.6 8.1e-05 22.2 0.0 5.5 5 1 0 5 5 5 3 Kelch motif DUF972 PF06156.8 KEP64908.1 - 0.01 16.1 2.5 0.019 15.2 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Leu_zip PF15294.1 KEP64908.1 - 0.021 13.9 2.6 0.028 13.5 1.8 1.1 1 0 0 1 1 1 0 Leucine zipper GAS PF13851.1 KEP64908.1 - 0.16 11.1 3.7 0.26 10.4 2.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tho2 PF11262.3 KEP64908.1 - 0.49 9.4 2.0 0.78 8.7 1.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DivIC PF04977.10 KEP64908.1 - 1.1 8.8 3.3 1.5 8.3 1.5 1.7 1 1 0 1 1 1 0 Septum formation initiator DUF904 PF06005.7 KEP64908.1 - 2.4 8.5 6.4 0.92 9.8 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) GED PF02212.13 KEP64909.1 - 0.13 12.2 0.2 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 Dynamin GTPase effector domain FHA PF00498.21 KEP64911.1 - 1.4e-16 60.3 1.9 9e-08 32.1 0.2 2.9 3 0 0 3 3 3 2 FHA domain zf-C3HC4_4 PF15227.1 KEP64911.1 - 1.6e-08 34.2 10.3 1.6e-08 34.2 7.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KEP64911.1 - 4.3e-08 32.8 10.9 1.5e-07 31.1 7.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEP64911.1 - 1.7e-07 30.7 7.6 4.3e-07 29.4 5.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP64911.1 - 2.4e-07 30.6 11.3 1.2e-06 28.4 7.8 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP64911.1 - 4.6e-07 29.3 10.3 1.3e-06 27.9 7.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP64911.1 - 7.3e-06 25.6 9.7 2.5e-05 23.9 6.7 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 KEP64911.1 - 6.4e-05 22.6 4.7 6.4e-05 22.6 3.2 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KEP64911.1 - 0.0019 17.8 7.2 0.0054 16.4 5.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KEP64911.1 - 0.0065 16.5 1.4 0.016 15.3 1.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger U-box PF04564.10 KEP64911.1 - 0.0099 15.8 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.1 KEP64911.1 - 0.015 14.8 3.2 0.033 13.7 2.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KEP64911.1 - 0.3 10.9 2.5 0.7 9.7 1.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Helicase_C PF00271.26 KEP64912.1 - 6.7e-15 54.7 0.0 1.5e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP64912.1 - 4e-13 49.2 0.0 3.4e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.11 KEP64912.1 - 0.027 13.7 0.0 1.5 8.0 0.0 2.6 3 0 0 3 3 3 0 PhoH-like protein Bul1_C PF04426.7 KEP64912.1 - 0.91 8.6 0.0 1.8 7.7 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus Isy1 PF06246.7 KEP64914.1 - 3.8e-78 262.4 5.0 4.6e-78 262.1 3.5 1.1 1 0 0 1 1 1 1 Isy1-like splicing family RabGAP-TBC PF00566.13 KEP64918.1 - 9e-46 156.0 0.2 1.7e-45 155.1 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4010 PF13194.1 KEP64919.1 - 0.5 9.6 6.2 0.84 8.8 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) ABC1 PF03109.11 KEP64920.1 - 8.1e-32 109.6 0.0 1.6e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family SlyX PF04102.7 KEP64920.1 - 0.056 13.8 1.2 0.19 12.1 0.8 1.9 1 0 0 1 1 1 0 SlyX HMG_box_2 PF09011.5 KEP64921.1 - 9e-12 45.1 12.3 3.9e-08 33.5 1.6 2.7 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KEP64921.1 - 1.3e-07 31.7 0.8 1.3e-07 31.7 0.6 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box Myb_DNA-binding PF00249.26 KEP64921.1 - 1.2e-05 25.3 0.0 2.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DDOST_48kD PF03345.9 KEP64923.1 - 1e-72 245.0 0.0 4.6e-66 223.1 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta Sigma70_r2 PF04542.9 KEP64927.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 2 SRP-alpha_N PF04086.8 KEP64927.1 - 4.7 6.5 8.8 5.4 6.3 6.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Seadorna_VP7 PF07387.6 KEP64928.1 - 0.083 11.7 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L2_C PF03947.13 KEP64929.1 - 2.2e-41 140.7 3.0 3.2e-41 140.1 2.1 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KEP64929.1 - 4.3e-17 61.8 0.1 9.8e-17 60.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Presenilin PF01080.12 KEP64930.1 - 1.6e-24 86.5 0.0 1.2e-11 44.1 0.0 3.0 3 0 0 3 3 3 2 Presenilin DUF4044 PF13253.1 KEP64930.1 - 0.13 11.4 4.2 0.23 10.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) Peptidase_S8 PF00082.17 KEP64931.1 - 2.6e-48 164.6 0.2 4.3e-48 163.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family SNARE PF05739.14 KEP64933.1 - 1.8e-09 37.1 3.0 1.8e-09 37.1 2.1 2.5 4 0 0 4 4 4 1 SNARE domain Syntaxin_2 PF14523.1 KEP64933.1 - 0.0021 18.0 7.6 0.0029 17.5 2.5 2.2 2 0 0 2 2 2 1 Syntaxin-like protein DUF4131 PF13567.1 KEP64933.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF892 PF05974.7 KEP64933.1 - 0.32 10.7 6.9 0.87 9.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF1664 PF07889.7 KEP64933.1 - 1.6 8.5 5.6 8.7 6.1 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-MIZ PF02891.15 KEP64936.1 - 4.9e-10 38.7 3.0 1.7e-09 37.0 2.1 2.0 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF629 PF04780.7 KEP64936.1 - 0.95 7.8 1.0 1.5 7.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) PHD PF00628.24 KEP64936.1 - 3.8 7.2 16.0 0.053 13.2 2.2 2.6 2 0 0 2 2 2 0 PHD-finger Dynein_light PF01221.13 KEP64937.1 - 5.6e-26 90.3 0.2 6.6e-26 90.1 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Cyclin PF08613.6 KEP64938.1 - 3.6e-14 53.4 0.0 2e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 KEP64938.1 - 0.01 15.4 0.0 0.44 10.1 0.0 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain RNA_pol_Rpb1_5 PF04998.12 KEP64939.1 - 4.1e-79 265.6 0.0 1.1e-78 264.3 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KEP64939.1 - 6.9e-49 165.9 0.3 3.9e-30 104.9 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KEP64939.1 - 1.2e-24 86.8 0.0 2.5e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KEP64939.1 - 2.4e-19 69.0 0.1 7.3e-19 67.5 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 KEP64939.1 - 2.2e-13 50.1 0.1 2.2e-13 50.1 0.1 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 ADH_zinc_N PF00107.21 KEP64940.1 - 1.9e-21 75.9 0.0 3.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEP64940.1 - 5.5e-11 43.4 0.0 1.2e-10 42.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEP64940.1 - 2.1e-09 37.1 0.0 9.2e-08 31.8 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.20 KEP64940.1 - 0.075 12.2 0.1 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme PH PF00169.24 KEP64941.1 - 5.5e-06 26.5 0.0 1.3e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 PH domain Sec3-PIP2_bind PF15277.1 KEP64941.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_6 PF15406.1 KEP64941.1 - 0.034 14.1 1.0 0.21 11.6 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain PH_11 PF15413.1 KEP64941.1 - 0.084 13.1 0.0 0.54 10.5 0.0 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain PH_4 PF15404.1 KEP64941.1 - 0.094 12.2 2.1 0.49 9.8 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4238 PF14022.1 KEP64941.1 - 0.68 9.1 4.2 0.22 10.7 1.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4238) Herpes_capsid PF06112.6 KEP64941.1 - 0.85 9.6 8.1 1.6 8.7 5.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GMC_oxred_C PF05199.8 KEP64942.1 - 1.1e-21 77.6 0.0 1.3e-16 61.1 0.0 2.6 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.14 KEP64942.1 - 1.2e-18 67.3 0.2 1.7e-08 33.9 0.0 3.2 3 0 0 3 3 3 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KEP64942.1 - 0.00013 21.9 0.1 0.00045 20.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEP64942.1 - 0.00017 20.5 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEP64942.1 - 0.00066 19.6 0.2 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEP64942.1 - 0.0016 17.0 0.0 0.0024 16.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KEP64942.1 - 0.0045 15.9 0.2 0.0085 15.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEP64942.1 - 0.012 15.9 0.0 0.035 14.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEP64942.1 - 0.022 14.8 0.4 0.2 11.7 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEP64942.1 - 0.031 13.1 0.1 0.049 12.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KEP64942.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 KEP64942.1 - 0.077 12.4 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SR-25 PF10500.4 KEP64943.1 - 2.6e-05 23.7 37.2 4e-05 23.2 25.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-CCHC_3 PF13917.1 KEP64943.1 - 3e-05 23.6 0.1 7.7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KEP64943.1 - 0.00016 21.4 2.2 0.00027 20.7 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KEP64943.1 - 0.004 16.6 0.3 0.004 16.6 0.2 2.2 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger RR_TM4-6 PF06459.7 KEP64943.1 - 2 8.2 16.7 2.6 7.8 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TATR PF03430.8 KEP64943.1 - 3.8 6.0 15.0 4.4 5.8 10.4 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF572 PF04502.8 KEP64943.1 - 3.9 6.6 22.5 5.3 6.1 15.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.4 KEP64943.1 - 5.1 5.8 18.3 6.6 5.4 12.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RXT2_N PF08595.6 KEP64944.1 - 0.77 9.5 7.0 2.8 7.7 3.9 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Adeno_terminal PF02459.10 KEP64944.1 - 2.5 6.1 9.4 4.3 5.3 6.5 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RNA_pol_Rpc4 PF05132.9 KEP64944.1 - 2.5 8.0 7.3 1.6 8.6 1.8 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM176 PF14851.1 KEP64944.1 - 4.4 6.9 13.4 3.1 7.4 3.3 3.0 3 0 0 3 3 3 0 FAM176 family Rhabdo_ncap PF00945.13 KEP64944.1 - 4.6 5.7 5.0 6.9 5.1 3.5 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein NAD_kinase PF01513.16 KEP64951.1 - 1.4e-60 204.5 0.0 2.7e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 KEP64951.1 - 0.089 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Mgm101p PF06420.7 KEP64953.1 - 0.051 12.8 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 A_deamin PF02137.13 KEP64954.1 - 3.2e-31 108.9 14.3 6.4e-22 78.3 0.0 5.4 4 1 1 5 5 5 3 Adenosine-deaminase (editase) domain WLM PF08325.5 KEP64956.1 - 9.7e-09 35.3 0.2 9.7e-09 35.3 0.1 3.2 3 2 0 3 3 3 1 WLM domain DUF45 PF01863.12 KEP64956.1 - 3.5e-05 23.6 0.3 7.9e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 eIF-5_eIF-2B PF01873.12 KEP64957.1 - 2.4e-36 124.1 0.0 5.6e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KEP64957.1 - 2.7e-13 49.6 0.2 2.7e-13 49.6 0.1 3.0 3 1 0 3 3 2 1 eIF4-gamma/eIF5/eIF2-epsilon CDC45 PF02724.9 KEP64957.1 - 7.1e-05 21.0 10.9 9.4e-05 20.6 7.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Mitofilin PF09731.4 KEP64957.1 - 0.033 12.8 19.0 0.044 12.4 13.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein eIF-3c_N PF05470.7 KEP64957.1 - 0.11 10.5 15.7 0.15 10.1 10.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TFIIF_alpha PF05793.7 KEP64957.1 - 0.15 10.3 36.9 0.22 9.8 25.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF262 PF03235.9 KEP64957.1 - 0.29 11.0 4.3 0.51 10.2 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 SAPS PF04499.10 KEP64957.1 - 0.68 8.4 10.2 0.83 8.2 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rtf2 PF04641.7 KEP64957.1 - 1.1 8.3 21.3 1.9 7.6 14.7 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.1 KEP64957.1 - 1.5 8.4 18.3 2.5 7.7 12.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MIP-T3 PF10243.4 KEP64957.1 - 2.4 6.5 34.3 3.2 6.1 23.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 KEP64957.1 - 3 6.9 33.2 4.2 6.4 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3883 PF13020.1 KEP64958.1 - 1.3e-10 40.8 0.0 2.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) TruD PF01142.13 KEP64960.1 - 1e-36 126.4 0.0 4.9e-10 38.6 0.0 4.3 4 0 0 4 4 4 4 tRNA pseudouridine synthase D (TruD) Herpes_DNAp_acc PF04929.7 KEP64961.1 - 0.0013 17.8 1.6 0.0013 17.8 1.1 2.4 1 1 1 2 2 2 1 Herpes DNA replication accessory factor Med18 PF09637.5 KEP64961.1 - 0.11 11.9 0.1 0.11 11.9 0.0 2.1 1 1 1 2 2 2 0 Med18 protein Sperm_Ag_HE2 PF05324.8 KEP64961.1 - 0.89 9.5 0.0 0.89 9.5 0.0 3.1 2 1 1 3 3 3 0 Sperm antigen HE2 Pkinase PF00069.20 KEP64962.1 - 1.9e-65 220.5 0.0 2.2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP64962.1 - 2.1e-40 138.4 0.0 2.5e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP64962.1 - 6.1e-08 31.9 0.0 8.9e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEP64962.1 - 0.0067 16.1 0.9 0.011 15.4 0.2 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEP64962.1 - 0.063 12.1 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KEP64962.1 - 0.087 12.1 0.1 0.44 9.8 0.0 1.8 1 1 1 2 2 2 0 RIO1 family zf-RING_2 PF13639.1 KEP64963.1 - 2.7e-11 43.0 6.8 4.6e-11 42.3 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEP64963.1 - 1.6e-08 34.0 4.3 2.8e-08 33.2 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP64963.1 - 5e-08 32.4 4.9 8.3e-08 31.7 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP64963.1 - 1.6e-07 31.2 4.4 3.2e-07 30.3 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEP64963.1 - 8.7e-07 28.8 6.2 1.5e-06 28.0 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP64963.1 - 8.3e-05 22.2 5.8 0.00017 21.2 3.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEP64963.1 - 0.00046 19.9 3.5 0.0011 18.7 2.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KEP64963.1 - 0.0045 16.7 2.2 0.0081 15.9 1.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEP64963.1 - 0.028 14.0 5.0 0.062 12.8 3.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KEP64963.1 - 0.03 14.1 1.0 0.03 14.1 0.7 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 KEP64963.1 - 0.034 13.6 2.1 0.082 12.3 1.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_UBOX PF13445.1 KEP64963.1 - 0.11 12.2 1.6 0.27 10.9 1.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger AAA PF00004.24 KEP64965.1 - 2.9e-37 127.8 0.0 5.1e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEP64965.1 - 2e-07 30.8 0.0 1.1e-05 25.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEP64965.1 - 2.8e-05 24.2 0.1 0.00054 20.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 KEP64965.1 - 0.00018 21.3 0.0 0.00059 19.6 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_19 PF13245.1 KEP64965.1 - 0.00073 19.2 0.0 0.0024 17.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KEP64965.1 - 0.0013 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEP64965.1 - 0.0015 17.5 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEP64965.1 - 0.0016 18.4 0.3 0.017 15.0 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KEP64965.1 - 0.002 17.5 0.0 0.0063 15.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 KEP64965.1 - 0.0022 18.7 0.0 0.0057 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AFG1_ATPase PF03969.11 KEP64965.1 - 0.0045 15.8 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_14 PF13173.1 KEP64965.1 - 0.0049 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 KEP64965.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEP64965.1 - 0.0072 15.5 0.1 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KEP64965.1 - 0.0099 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KEP64965.1 - 0.015 15.4 0.3 0.43 10.7 0.0 3.2 4 0 0 4 4 3 0 RNA helicase AAA_25 PF13481.1 KEP64965.1 - 0.023 14.1 0.9 0.062 12.6 0.6 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KEP64965.1 - 0.051 13.2 0.2 1.8 8.1 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.1 KEP64965.1 - 0.056 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEP64965.1 - 0.07 13.4 0.5 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KEP64965.1 - 0.098 11.3 0.0 0.24 10.0 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus ABC_tran PF00005.22 KEP64965.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.11 KEP64965.1 - 0.17 11.0 0.1 0.32 10.1 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 KEP64965.1 - 0.22 11.0 0.0 0.42 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L1 PF00687.16 KEP64966.1 - 2.7e-27 95.5 0.0 8.4e-25 87.3 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family Nop14 PF04147.7 KEP64967.1 - 0.047 11.6 38.4 0.049 11.5 26.6 1.0 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 KEP64967.1 - 0.25 10.7 18.3 0.29 10.5 12.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 KEP64967.1 - 0.28 9.6 41.3 0.34 9.3 28.6 1.1 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 KEP64967.1 - 0.37 10.0 25.5 0.38 9.9 17.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pilt PF15453.1 KEP64967.1 - 0.61 9.7 14.7 0.77 9.3 10.2 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF1510 PF07423.6 KEP64967.1 - 0.7 9.2 28.3 0.98 8.7 19.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KEP64967.1 - 0.71 7.8 21.8 0.84 7.5 15.1 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 KEP64967.1 - 0.89 8.7 37.2 1 8.6 25.8 1.2 1 0 0 1 1 1 0 SDA1 MIP-T3 PF10243.4 KEP64967.1 - 0.93 7.8 25.2 1.1 7.6 17.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HSP90 PF00183.13 KEP64969.1 - 5.7e-173 576.1 40.0 5.7e-173 576.1 27.7 1.8 1 1 1 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.1 KEP64969.1 - 5e-13 48.8 0.0 5e-13 48.8 0.0 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEP64969.1 - 1.5e-10 40.8 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pox_P35 PF03213.9 KEP64969.1 - 2.3 7.1 11.9 0.21 10.5 4.3 2.0 2 0 0 2 2 2 0 Poxvirus P35 protein RskA PF10099.4 KEP64970.1 - 0.047 13.4 6.5 0.14 11.9 0.7 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Mito_carr PF00153.22 KEP64971.1 - 6.9e-12 44.9 0.8 6.1e-08 32.2 0.1 3.5 3 1 0 3 3 3 2 Mitochondrial carrier protein RsbRD_N PF14361.1 KEP64972.1 - 0.15 12.5 5.0 0.35 11.3 0.7 2.7 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Glycos_transf_4 PF00953.16 KEP64973.1 - 1.2e-30 106.4 22.3 9.2e-24 84.0 6.4 2.9 3 1 0 3 3 3 2 Glycosyl transferase family 4 AP2 PF00847.15 KEP64975.1 - 0.051 13.7 3.8 0.11 12.6 2.7 1.6 1 0 0 1 1 1 0 AP2 domain TTL PF03133.10 KEP64976.1 - 1.4e-57 194.9 0.6 2.5e-57 194.0 0.4 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEP64976.1 - 8.2e-07 28.0 0.2 0.00015 20.6 0.0 3.0 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 KEP64976.1 - 0.032 13.9 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.6 KEP64976.1 - 0.16 11.4 0.0 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 KEP64976.1 - 0.58 9.2 0.0 1.1 8.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Peptidase_M16 PF00675.15 KEP64977.1 - 4.5e-37 127.1 0.0 1.1e-36 125.8 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEP64977.1 - 1.1e-24 87.1 0.0 7.1e-17 61.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF3218 PF11508.3 KEP64978.1 - 1.4 8.3 3.7 7.3 6.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3218) La PF05383.12 KEP64980.1 - 0.047 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 La domain PP2C PF00481.16 KEP64981.1 - 1.4e-37 129.5 0.1 6.8e-34 117.3 0.0 3.1 2 1 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.7 KEP64981.1 - 3.1e-05 23.7 0.0 0.00021 21.0 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Nucleoside_tran PF01733.13 KEP64982.1 - 2.2e-19 69.7 3.2 4.3e-19 68.8 2.2 1.5 1 0 0 1 1 1 1 Nucleoside transporter PseudoU_synth_2 PF00849.17 KEP64983.1 - 3e-12 46.6 0.0 5.9e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 KEP64983.1 - 0.00039 19.7 0.0 0.00094 18.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain ORC6 PF05460.8 KEP64983.1 - 0.038 13.0 0.0 0.084 11.9 0.0 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF947 PF06102.7 KEP64984.1 - 2.7e-26 92.3 16.2 1.1e-25 90.3 6.9 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF947) CDO_I PF05995.7 KEP64985.1 - 7.5e-14 51.2 0.2 7.5e-14 51.2 0.1 2.0 2 0 0 2 2 2 1 Cysteine dioxygenase type I Pyridoxal_deC PF00282.14 KEP64985.1 - 2.2e-09 36.2 0.0 4.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF3633 PF12315.3 KEP64986.1 - 9.6e-19 67.5 0.5 5.2e-17 61.8 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3633) Peptidase_MA_2 PF13485.1 KEP64986.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Coatomer_E PF04733.9 KEP64987.1 - 8.4e-34 117.0 0.1 1e-33 116.7 0.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_1 PF00515.23 KEP64987.1 - 0.0017 17.8 1.3 8.2 6.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEP64987.1 - 0.01 15.4 4.2 0.49 10.0 0.2 3.4 2 2 0 3 3 3 0 TPR repeat PRA-PH PF01503.12 KEP64987.1 - 0.12 12.6 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase TPR_12 PF13424.1 KEP64987.1 - 0.19 11.7 4.4 0.86 9.5 0.0 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP64987.1 - 0.6 10.1 10.2 3.8 7.6 0.2 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat CactinC_cactus PF09732.4 KEP64988.1 - 3.5e-53 178.4 7.4 6.5e-53 177.5 5.1 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 KEP64988.1 - 5.5e-34 117.1 1.9 1.9e-33 115.3 1.3 2.0 1 0 0 1 1 1 1 Conserved mid region of cactin SUFU_C PF12470.3 KEP64988.1 - 0.03 13.9 5.3 0.017 14.7 1.4 2.2 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain SNARE_assoc PF09335.6 KEP64989.1 - 4.8e-09 36.4 3.3 4.8e-09 36.4 2.3 3.0 3 0 0 3 3 3 1 SNARE associated Golgi protein Ctr PF04145.10 KEP64989.1 - 0.012 15.6 0.0 0.055 13.5 0.0 2.0 2 0 0 2 2 2 0 Ctr copper transporter family P12 PF12669.2 KEP64989.1 - 3.9 7.7 9.4 11 6.3 4.6 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family OHA PF14418.1 KEP64990.1 - 9.3e-25 85.9 0.0 2.6e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 OST-HTH Associated domain DUF3395 PF11875.3 KEP64991.1 - 2.3e-26 92.2 0.6 4.4e-26 91.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KEP64991.1 - 2.1e-17 62.6 1.3 3.6e-17 61.8 0.0 2.1 3 0 0 3 3 3 1 DnaJ domain DUF3012 PF11216.3 KEP64993.1 - 0.054 13.1 0.1 13 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) Ribosomal_L24e PF01246.15 KEP64994.1 - 5.5e-21 74.1 1.1 1.3e-20 72.9 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF775 PF05603.7 KEP64994.1 - 0.025 14.1 1.5 0.028 13.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF2951 PF11166.3 KEP64994.1 - 0.43 10.4 2.8 7.7 6.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) TGS PF02824.16 KEP64995.1 - 1.4e-19 69.6 0.1 2.8e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KEP64995.1 - 1.5e-19 70.0 0.1 3.8e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP64995.1 - 1.3e-11 43.9 0.2 4.6e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEP64995.1 - 2.5e-05 24.1 0.2 0.13 12.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KEP64995.1 - 0.00027 19.8 0.3 0.0019 17.0 0.1 2.1 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KEP64995.1 - 0.0019 18.6 0.1 0.0051 17.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KEP64995.1 - 0.0044 16.4 0.3 1.7 8.0 0.0 3.5 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KEP64995.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.5 KEP64995.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KEP64995.1 - 0.17 11.8 0.1 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Adaptin_N PF01602.15 KEP64997.1 - 2.1e-73 247.4 7.7 4.5e-68 229.8 6.4 2.2 2 0 0 2 2 2 2 Adaptin N terminal region AP4E_app_platf PF14807.1 KEP64997.1 - 9.8e-12 45.0 0.0 2.9e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.1 KEP64997.1 - 4.6e-05 23.6 11.6 0.0019 18.4 0.4 5.0 4 1 1 5 5 5 2 HEAT repeats Cnd1 PF12717.2 KEP64997.1 - 0.027 14.3 2.4 1.5 8.6 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KEP64997.1 - 0.037 14.5 8.2 0.076 13.5 0.3 4.3 4 0 0 4 4 4 0 HEAT-like repeat NUC130_3NT PF08158.7 KEP64997.1 - 0.17 12.2 2.6 2.7 8.3 0.0 3.5 3 0 0 3 3 3 0 NUC130/3NT domain ParcG PF10274.4 KEP64997.1 - 0.17 11.7 3.3 4.6 7.1 0.0 3.1 3 1 0 3 3 3 0 Parkin co-regulated protein HEAT PF02985.17 KEP64997.1 - 0.26 11.4 6.4 0.73 10.0 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat ABC_tran PF00005.22 KEP64999.1 - 9.6e-23 80.9 0.1 2.1e-22 79.9 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC2_membrane PF01061.19 KEP64999.1 - 1.3e-21 76.7 26.8 1.8e-21 76.2 18.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_25 PF13481.1 KEP64999.1 - 1.4e-05 24.5 0.1 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEP64999.1 - 0.00013 22.1 0.1 0.00042 20.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KEP64999.1 - 0.0015 19.2 0.0 0.0035 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KEP64999.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 KEP64999.1 - 0.0021 17.7 0.2 0.0041 16.8 0.2 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KEP64999.1 - 0.0025 17.3 0.2 0.0069 15.9 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KEP64999.1 - 0.0043 17.0 1.6 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KEP64999.1 - 0.0058 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 KEP64999.1 - 0.011 15.7 0.0 0.057 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEP64999.1 - 0.015 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RecA PF00154.16 KEP64999.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_33 PF13671.1 KEP64999.1 - 0.027 14.3 0.3 0.063 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 KEP64999.1 - 0.036 14.3 0.0 0.036 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 KEP64999.1 - 0.045 13.7 1.4 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KEP64999.1 - 0.047 12.8 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KEP64999.1 - 0.059 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 KEP64999.1 - 0.078 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 KEP64999.1 - 0.083 12.1 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC2_membrane_3 PF12698.2 KEP64999.1 - 0.12 11.3 28.1 0.034 13.1 17.3 1.5 1 1 1 2 2 2 0 ABC-2 family transporter protein MMR_HSR1 PF01926.18 KEP64999.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 KEP64999.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KEP64999.1 - 0.2 11.1 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TMPIT PF07851.8 KEP65000.1 - 0.15 11.0 0.5 0.2 10.7 0.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF883 PF05957.8 KEP65000.1 - 0.48 10.8 2.6 0.71 10.3 1.0 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Methyltransf_26 PF13659.1 KEP65002.1 - 1.1e-08 35.0 0.0 3.9e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEP65002.1 - 0.03 13.6 0.0 0.32 10.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase small domain Rhomboid PF01694.17 KEP65003.1 - 4.5e-05 23.5 2.4 0.01 15.8 0.0 2.5 3 0 0 3 3 3 2 Rhomboid family Plus-3 PF03126.13 KEP65004.1 - 1.9e-05 24.6 0.0 0.00013 21.9 0.0 2.2 1 1 0 1 1 1 1 Plus-3 domain Glyco_hydro_67N PF03648.9 KEP65004.1 - 0.16 12.0 0.4 0.41 10.6 0.3 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus NPV_P10 PF05531.7 KEP65004.1 - 1.3 9.2 3.1 20 5.5 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Transket_pyr PF02779.19 KEP65005.1 - 6.6e-61 204.8 0.0 1.1e-60 204.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KEP65005.1 - 1.8e-53 181.2 0.0 2.7e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Borrelia_P83 PF05262.6 KEP65006.1 - 1.4 7.1 6.5 1.9 6.6 4.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein cEGF PF12662.2 KEP65007.1 - 2.2e-05 23.9 91.5 0.019 14.5 1.3 10.7 11 0 0 11 11 11 7 Complement Clr-like EGF-like EGF_3 PF12947.2 KEP65007.1 - 0.00055 19.8 10.8 0.00055 19.8 7.5 11.4 10 2 0 10 10 10 5 EGF domain EGF_MSP1_1 PF12946.2 KEP65007.1 - 0.0032 17.1 2.3 0.0032 17.1 1.6 10.3 9 1 0 9 9 9 4 MSP1 EGF domain 1 EGF PF00008.22 KEP65007.1 - 4.7 7.2 129.9 0.23 11.4 2.2 12.7 11 1 0 11 11 11 0 EGF-like domain HIG_1_N PF04588.8 KEP65008.1 - 0.15 11.8 1.4 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 Hypoxia induced protein conserved region TFIID_20kDa PF03847.8 KEP65009.1 - 7.7e-06 26.1 0.1 1.9e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KEP65009.1 - 0.0055 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 KEP65009.1 - 0.023 14.4 0.0 0.071 12.9 0.0 1.8 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF3348 PF11828.3 KEP65010.1 - 0.18 11.1 4.7 0.03 13.7 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) UPF0081 PF03652.10 KEP65011.1 - 7.3e-07 29.3 0.0 0.05 13.7 0.0 3.3 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0081) DUF2572 PF10833.3 KEP65012.1 - 1.2 8.4 0.2 2 7.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) zf-CW PF07496.10 KEP65013.1 - 1.4e-05 24.7 11.0 3.2e-05 23.5 7.7 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger PrmA PF06325.8 KEP65014.1 - 0.0045 16.1 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NAP PF00956.13 KEP65015.1 - 8.5e-70 234.6 1.6 8.5e-70 234.6 1.1 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF1640 PF07798.6 KEP65015.1 - 4.9 7.1 7.9 2.1 8.3 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Prp31_C PF09785.4 KEP65016.1 - 9e-32 110.1 6.1 2.2e-31 108.8 4.2 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KEP65016.1 - 1.3e-31 108.9 4.8 4e-31 107.3 1.8 2.6 3 0 0 3 3 3 1 Putative snoRNA binding domain NOSIC PF08060.8 KEP65016.1 - 6.3e-17 61.1 0.7 1.4e-16 60.0 0.5 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain DUF2098 PF09871.4 KEP65016.1 - 0.13 12.1 1.8 0.26 11.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) DUF4072 PF13284.1 KEP65019.1 - 0.11 12.6 1.4 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) Ank PF00023.25 KEP65020.1 - 9.2e-18 63.0 1.9 7.4e-05 22.3 0.1 5.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 KEP65020.1 - 1.1e-17 64.1 0.0 1.3e-09 38.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEP65020.1 - 1.5e-13 49.5 0.1 0.1 12.8 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KEP65020.1 - 2.6e-09 37.0 0.8 0.17 12.2 0.0 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEP65020.1 - 5.2e-09 36.3 0.0 0.00012 22.5 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PPR_2 PF13041.1 KEP65021.1 - 6.3e-08 32.4 0.0 0.0026 17.6 0.0 4.6 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.15 KEP65021.1 - 1.4e-05 24.6 1.0 0.72 9.9 0.0 5.4 5 0 0 5 5 5 1 PPR repeat TPR_7 PF13176.1 KEP65021.1 - 0.02 14.6 6.4 0.1 12.4 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEP65021.1 - 0.036 13.8 0.1 0.096 12.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP65021.1 - 0.067 13.1 0.1 0.067 13.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP65021.1 - 0.099 12.2 0.2 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PPR_3 PF13812.1 KEP65021.1 - 0.15 12.4 9.4 13 6.3 0.0 6.0 6 0 0 6 6 6 0 Pentatricopeptide repeat domain TPR_2 PF07719.12 KEP65021.1 - 0.36 10.8 4.0 0.24 11.4 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.2 KEP65022.1 - 3.2e-38 130.0 0.1 2e-15 56.9 0.0 5.2 5 0 0 5 5 5 3 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.3 KEP65022.1 - 5.3e-24 84.3 5.9 6.1e-20 71.1 3.0 3.4 2 1 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.17 KEP65022.1 - 3.4e-10 39.1 6.8 0.0046 16.9 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KEP65022.1 - 0.00032 21.0 18.8 0.027 14.9 0.2 6.1 6 1 1 7 7 7 2 HEAT-like repeat Cnd1 PF12717.2 KEP65022.1 - 0.0029 17.4 1.8 7.5 6.3 0.1 4.6 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEP65022.1 - 0.0031 17.7 11.2 0.64 10.3 0.0 5.2 5 0 0 5 5 5 2 HEAT repeats CLASP_N PF12348.3 KEP65022.1 - 0.0057 16.0 0.0 0.074 12.3 0.0 2.9 4 0 0 4 4 4 1 CLASP N terminal DUF2454 PF10521.4 KEP65022.1 - 0.0089 15.0 0.1 3.4 6.5 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) Mpp10 PF04006.7 KEP65022.1 - 0.72 8.1 31.0 0.16 10.3 6.0 2.2 2 0 0 2 2 2 0 Mpp10 protein SAPS PF04499.10 KEP65022.1 - 1.4 7.4 10.8 0.92 8.0 0.3 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Tetraspannin PF00335.15 KEP65023.1 - 0.73 9.0 7.0 0.15 11.2 1.8 2.0 2 0 0 2 2 2 0 Tetraspanin family ORF6C PF10552.4 KEP65024.1 - 0.011 15.4 0.9 0.033 13.9 0.1 2.1 2 1 0 2 2 2 0 ORF6C domain HisKA_3 PF07730.8 KEP65024.1 - 0.072 13.4 5.4 5.2 7.4 0.0 3.5 2 1 0 2 2 2 0 Histidine kinase Med9 PF07544.8 KEP65024.1 - 0.099 12.3 0.4 0.099 12.3 0.3 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 XH PF03469.9 KEP65024.1 - 0.12 12.0 6.9 0.11 12.2 2.9 2.3 1 1 1 2 2 2 0 XH domain TBPIP PF07106.8 KEP65024.1 - 1 8.9 10.4 0.18 11.3 2.9 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIVA PF05103.8 KEP65024.1 - 2.9 7.9 12.3 37 4.3 7.2 2.7 1 1 1 2 2 2 0 DivIVA protein Prefoldin_2 PF01920.15 KEP65024.1 - 3.2 7.5 11.7 8.3 6.2 2.3 3.5 3 1 0 3 3 3 0 Prefoldin subunit IFT57 PF10498.4 KEP65025.1 - 3.7e-06 25.9 1.7 4.4e-06 25.6 1.1 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF1690 PF07956.6 KEP65025.1 - 0.0035 17.3 4.5 0.0042 17.0 2.8 1.3 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Lectin_N PF03954.9 KEP65025.1 - 0.0059 15.9 1.1 0.0087 15.4 0.8 1.2 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain Mating_N PF12731.2 KEP65025.1 - 0.0095 15.7 0.5 0.018 14.9 0.4 1.4 1 0 0 1 1 1 1 Mating-type protein beta 1 IncA PF04156.9 KEP65025.1 - 0.055 13.0 4.6 0.066 12.8 3.2 1.3 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 KEP65025.1 - 0.11 12.3 0.4 0.2 11.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) LPP PF04728.8 KEP65026.1 - 0.12 12.1 0.5 0.26 11.1 0.4 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper AHSA1 PF08327.6 KEP65027.1 - 1.7e-19 70.1 0.1 1.9e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Peptidase_M13_N PF05649.8 KEP65027.1 - 0.012 14.7 0.0 0.012 14.6 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M13 Cloacin_immun PF03513.9 KEP65027.1 - 0.049 13.6 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Cloacin immunity protein HORMA PF02301.13 KEP65028.1 - 7.3e-09 35.4 0.0 1.9e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 HORMA domain DEAD PF00270.24 KEP65029.1 - 2e-42 144.5 0.0 4.4e-42 143.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP65029.1 - 6.3e-15 54.8 0.8 5.4e-06 26.1 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF4217 PF13959.1 KEP65029.1 - 7.6e-13 47.8 0.0 1.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Herpes_capsid PF06112.6 KEP65029.1 - 6.6 6.7 26.9 1.1 9.3 12.0 2.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein NIF PF03031.13 KEP65030.1 - 5.9e-37 126.7 0.0 8e-37 126.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-HC2 PF13490.1 KEP65030.1 - 0.0057 16.5 1.4 3 7.8 0.3 2.8 2 0 0 2 2 2 2 Putative zinc-finger HAD_2 PF13419.1 KEP65030.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3377 PF11857.3 KEP65030.1 - 0.021 14.4 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) MRC1 PF09444.5 KEP65030.1 - 0.14 12.4 2.2 0.21 11.9 1.6 1.2 1 0 0 1 1 1 0 MRC1-like domain TMF_DNA_bd PF12329.3 KEP65031.1 - 0.0019 17.9 1.5 0.0019 17.9 1.0 2.8 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 KEP65031.1 - 0.002 17.1 1.3 0.0023 16.9 0.9 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 KEP65031.1 - 0.24 11.1 4.9 2.6 7.8 0.1 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper CENP-H PF05837.7 KEP65031.1 - 0.29 11.3 3.7 0.4 10.8 2.6 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.6 KEP65031.1 - 0.57 8.7 3.5 0.7 8.4 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 KEP65031.1 - 0.9 9.0 3.6 7 6.2 0.2 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4200 PF13863.1 KEP65031.1 - 1.3 8.9 10.6 0.21 11.5 1.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4140 PF13600.1 KEP65031.1 - 1.5 9.2 5.2 2.8 8.4 1.2 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KEP65031.1 - 3.4 7.2 7.6 4.6 6.7 5.2 1.2 1 0 0 1 1 1 0 IncA protein NTF2 PF02136.15 KEP65033.1 - 1.2e-15 57.8 0.1 2.1e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Band_7 PF01145.20 KEP65034.1 - 6.9e-28 97.7 0.7 1.3e-26 93.6 0.1 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family BMC PF00936.14 KEP65034.1 - 0.1 12.3 0.5 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 BMC domain Med2 PF11214.3 KEP65034.1 - 0.11 12.6 0.6 0.19 11.7 0.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 MCM PF00493.18 KEP65038.1 - 5.3e-128 426.4 0.0 7e-128 426.0 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 KEP65038.1 - 6.6e-08 31.9 0.1 8.3e-06 25.1 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 KEP65038.1 - 5.5e-06 26.8 0.0 1.5e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 KEP65038.1 - 0.0021 17.7 0.0 0.0092 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEP65038.1 - 0.0033 17.0 0.0 0.013 15.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEP65038.1 - 0.021 14.2 0.0 0.18 11.2 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Baculo_VP91_N PF08475.5 KEP65038.1 - 0.035 13.4 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Hydrolase_3 PF08282.7 KEP65039.1 - 7.4e-49 166.6 0.0 8.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEP65039.1 - 6.3e-11 42.0 0.0 4.1e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 KEP65039.1 - 6e-06 26.8 0.0 1.5e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP65039.1 - 0.0013 18.9 0.1 0.11 12.5 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase AMP-binding PF00501.23 KEP65040.1 - 5.7e-72 242.4 0.0 1.5e-71 240.9 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEP65040.1 - 0.00056 20.8 0.5 0.003 18.4 0.3 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAG PF04092.8 KEP65041.1 - 0.00072 19.9 0.0 0.0012 19.2 0.0 1.5 1 1 0 1 1 1 1 SRS domain TOBE PF03459.12 KEP65041.1 - 0.02 14.9 0.7 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 TOBE domain DUF543 PF04418.7 KEP65041.1 - 0.61 10.0 2.6 0.85 9.6 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Cyclin_N PF00134.18 KEP65042.1 - 0.051 13.1 1.7 0.064 12.8 0.1 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain TRAM_LAG1_CLN8 PF03798.11 KEP65043.1 - 3e-12 46.5 23.4 3e-12 46.5 16.2 2.6 2 1 0 3 3 3 1 TLC domain TPR_11 PF13414.1 KEP65044.1 - 0.0027 17.3 0.1 0.0051 16.4 0.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KEP65044.1 - 0.0039 16.9 0.5 0.0088 15.8 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.13 KEP65044.1 - 0.061 13.2 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain WD40 PF00400.27 KEP65045.1 - 5.1e-45 149.7 30.6 3.8e-10 39.2 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Myb_DNA-bind_5 PF13873.1 KEP65045.1 - 0.073 12.9 4.4 0.27 11.1 3.1 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain APG6 PF04111.7 KEP65045.1 - 0.094 11.7 22.3 0.053 12.5 6.5 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 KEP65045.1 - 1.2 7.4 16.2 0.051 12.0 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) THP2 PF09432.5 KEP65045.1 - 1.4 8.7 7.2 1.5 8.7 3.9 1.8 1 1 0 1 1 1 0 Tho complex subunit THP2 DUF4200 PF13863.1 KEP65045.1 - 1.9 8.4 22.9 0.85 9.5 10.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HALZ PF02183.13 KEP65045.1 - 3.8 7.3 15.0 0.49 10.1 0.6 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper CENP-Q PF13094.1 KEP65045.1 - 4.9 7.1 25.2 0.85 9.6 0.3 4.1 3 2 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Acid_PPase PF12689.2 KEP65046.1 - 0.025 14.2 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase PEX11 PF05648.9 KEP65047.1 - 6.5e-45 153.1 1.1 1.2e-44 152.2 0.7 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cpn60_TCP1 PF00118.19 KEP65048.1 - 2.2e-124 415.7 4.4 5.6e-93 312.1 0.3 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family DUF3093 PF11292.3 KEP65049.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) DapB_C PF05173.9 KEP65050.1 - 1.2e-39 135.0 0.3 1.8e-39 134.5 0.2 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.15 KEP65050.1 - 2.7e-24 85.4 0.1 5.9e-23 81.1 0.1 2.4 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KEP65050.1 - 0.02 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_3 PF03447.11 KEP65050.1 - 0.021 15.2 0.0 0.041 14.2 0.0 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain HEAT_2 PF13646.1 KEP65051.1 - 0.12 12.6 4.1 0.099 12.9 0.4 2.6 3 0 0 3 3 3 0 HEAT repeats GMC_oxred_C PF05199.8 KEP65052.1 - 3.1e-16 59.9 0.0 4e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.14 KEP65052.1 - 1.5e-10 40.6 0.1 4.5e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase OmdA PF13376.1 KEP65052.1 - 0.17 11.5 1.6 0.23 11.1 0.2 1.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated BCAS2 PF05700.6 KEP65054.1 - 3.2e-27 95.4 6.7 6.5e-23 81.3 1.9 2.1 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 2 (BCAS2) Myco_19_kDa PF05481.7 KEP65054.1 - 0.42 10.4 3.4 0.71 9.6 2.4 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen DNA_methylase PF00145.12 KEP65055.1 - 2.9e-23 82.5 0.0 1.2e-14 54.1 0.0 3.4 4 0 0 4 4 4 2 C-5 cytosine-specific DNA methylase Acetyltransf_1 PF00583.19 KEP65056.1 - 4.6e-12 45.7 0.1 7.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEP65056.1 - 2.1e-08 33.7 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KEP65056.1 - 2e-06 27.8 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEP65056.1 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEP65056.1 - 4.5e-05 23.2 0.0 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KEP65056.1 - 0.0054 16.8 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEP65056.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4551 PF15087.1 KEP65057.1 - 0.16 10.3 13.6 0.19 10.0 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GvpH PF05455.6 KEP65057.1 - 0.16 11.5 4.3 0.39 10.3 3.0 1.6 1 0 0 1 1 1 0 GvpH Exo_endo_phos PF03372.18 KEP65058.1 - 7.1e-13 49.0 0.0 1.4e-12 48.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Herpes_UL3 PF03369.8 KEP65058.1 - 0.16 11.9 0.2 0.41 10.5 0.1 1.7 2 0 0 2 2 2 0 Herpesvirus UL3 protein HIT PF01230.18 KEP65059.1 - 1.4e-25 89.6 0.0 2.1e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEP65059.1 - 1.5e-10 41.3 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ribosomal_S26e PF01283.14 KEP65060.1 - 2e-50 169.7 8.0 2.2e-50 169.6 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.12 KEP65060.1 - 0.071 13.7 0.6 0.1 13.2 0.4 1.3 1 0 0 1 1 1 0 SRP19 protein Fer4_9 PF13187.1 KEP65060.1 - 0.5 10.6 5.1 1.1 9.5 3.4 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 KEP65060.1 - 0.72 9.6 5.5 1.4 8.8 3.8 1.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF4496 PF14908.1 KEP65061.1 - 1.1e-36 125.8 0.0 1.3e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) Bac_DNA_binding PF00216.16 KEP65061.1 - 0.0028 17.6 0.0 0.031 14.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial DNA-binding protein Peptidase_C23 PF05379.6 KEP65061.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Carlavirus endopeptidase Neuropep_like PF15161.1 KEP65061.1 - 0.1 12.1 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Neuropeptide-like SHIPPO-rpt PF07004.7 KEP65062.1 - 1.4e-33 114.0 65.0 0.0002 22.0 0.2 10.4 10 0 0 10 10 10 10 Sperm-tail PG-rich repeat ECR1_N PF14382.1 KEP65062.1 - 0.36 10.1 12.4 4.2 6.7 0.1 6.3 6 1 1 7 7 7 0 Exosome complex exonuclease RRP4 N-terminal region DUF4452 PF14618.1 KEP65063.1 - 0.95 9.2 6.1 1.1 9.0 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) WD40 PF00400.27 KEP65064.1 - 6.9e-55 181.0 8.9 1.2e-09 37.6 0.0 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat PRP4 PF08799.6 KEP65064.1 - 2e-11 42.9 1.1 2e-11 42.9 0.7 2.6 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 KEP65064.1 - 0.016 13.3 8.3 1.1 7.3 0.2 4.4 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEP65064.1 - 0.03 13.1 0.0 0.44 9.2 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Nbas_N PF15492.1 KEP65064.1 - 0.049 12.7 0.1 0.86 8.6 0.0 2.6 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 KEP65064.1 - 0.21 9.3 0.1 0.42 8.3 0.1 1.4 1 0 0 1 1 1 0 IKI3 family PPR_2 PF13041.1 KEP65065.1 - 3e-41 139.1 0.1 7.2e-10 38.6 0.0 7.9 4 2 3 7 7 7 7 PPR repeat family PPR_3 PF13812.1 KEP65065.1 - 8e-24 81.8 16.3 0.00019 21.4 0.0 10.2 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 KEP65065.1 - 1.7e-22 77.7 4.4 0.00043 20.0 0.0 9.6 10 0 0 10 10 10 6 PPR repeat PPR_1 PF12854.2 KEP65065.1 - 1.1e-19 69.6 0.8 0.0013 18.1 0.0 8.1 8 0 0 8 8 8 5 PPR repeat TPR_14 PF13428.1 KEP65065.1 - 2.7e-05 24.3 2.3 8.2 7.3 0.3 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat ECSIT PF06239.6 KEP65065.1 - 0.025 13.4 0.0 15 4.3 0.0 4.1 5 0 0 5 5 5 0 Evolutionarily conserved signalling intermediate in Toll pathway OTU PF02338.14 KEP65066.1 - 3.2e-15 56.7 0.9 6.1e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KEP65066.1 - 1.1e-06 28.2 0.3 0.00041 19.7 0.0 2.6 2 1 1 3 3 3 2 Peptidase C65 Otubain Pkinase PF00069.20 KEP65067.1 - 5.2e-66 222.4 0.1 6.5e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65067.1 - 6.5e-41 140.1 0.0 8.2e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP65067.1 - 4.5e-10 38.9 0.0 5.4e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KEP65067.1 - 1.9e-05 24.0 0.4 3.1e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KEP65067.1 - 3.9e-05 22.7 0.2 8.8e-05 21.6 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP65067.1 - 0.017 14.8 0.1 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DCX PF03607.12 KEP65067.1 - 0.078 12.5 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Doublecortin BCS1_N PF08740.6 KEP65068.1 - 2.5e-40 138.0 0.2 2.5e-40 138.0 0.1 2.2 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KEP65068.1 - 4.7e-16 59.1 0.0 8.6e-15 55.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEP65068.1 - 0.00033 21.4 0.0 0.00095 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEP65068.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEP65068.1 - 0.0022 17.4 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP65068.1 - 0.0023 17.8 0.2 0.0085 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain PPV_E1_C PF00519.12 KEP65068.1 - 0.0038 15.8 0.0 0.0057 15.3 0.0 1.1 1 0 0 1 1 1 1 Papillomavirus helicase AAA_16 PF13191.1 KEP65068.1 - 0.0042 17.0 0.3 0.015 15.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KEP65068.1 - 0.0047 16.0 0.0 0.0085 15.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KEP65068.1 - 0.011 15.3 0.2 0.063 12.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEP65068.1 - 0.012 15.7 0.0 0.042 14.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KEP65068.1 - 0.013 15.2 0.0 0.47 10.1 0.0 2.7 2 1 1 3 3 3 0 NACHT domain AAA_14 PF13173.1 KEP65068.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEP65068.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEP65068.1 - 0.018 15.3 0.0 1.7 8.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.22 KEP65068.1 - 0.044 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 KEP65068.1 - 0.053 13.4 0.2 0.96 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 KEP65068.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC Rad17 PF03215.10 KEP65068.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KEP65068.1 - 0.12 12.1 0.0 0.49 10.1 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain Ribosomal_L3 PF00297.17 KEP65069.1 - 1.9e-24 86.5 1.4 4e-22 78.8 1.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L3 NosL PF05573.7 KEP65071.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 NosL MCLC PF05934.6 KEP65072.1 - 1.1 7.4 7.8 2 6.6 5.4 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Ras PF00071.17 KEP65073.1 - 3.9e-54 182.4 0.0 5.5e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP65073.1 - 9.1e-18 64.8 0.0 1.6e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP65073.1 - 1.1e-15 57.3 0.0 1.6e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEP65073.1 - 6e-06 25.5 0.0 8.2e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEP65073.1 - 7.6e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP65073.1 - 2.5e-05 23.7 0.0 0.00014 21.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KEP65073.1 - 0.0064 15.7 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Bromodomain PF00439.20 KEP65074.1 - 4.9e-22 77.6 1.9 8.2e-22 76.9 0.9 1.7 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 KEP65074.1 - 4.5e-11 42.7 1.5 9.1e-11 41.7 1.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEP65074.1 - 9.2e-11 41.6 0.6 3.4e-10 39.7 0.1 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEP65074.1 - 8.5e-06 25.8 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP65074.1 - 0.0023 17.6 0.1 0.0068 16.1 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KEP65074.1 - 0.0043 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEP65074.1 - 0.0094 16.1 0.1 0.059 13.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain OTU PF02338.14 KEP65075.1 - 1.4e-17 64.4 0.0 3.2e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KEP65075.1 - 2.7e-06 26.9 0.2 0.015 14.6 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain Death PF00531.17 KEP65075.1 - 0.064 13.0 0.9 0.15 11.8 0.6 1.5 1 0 0 1 1 1 0 Death domain TPR_11 PF13414.1 KEP65076.1 - 1.6e-07 30.8 0.1 0.00065 19.2 0.0 2.6 1 1 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.1 KEP65076.1 - 1.7e-07 30.9 0.2 0.0062 16.4 0.2 2.4 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 KEP65076.1 - 2.4e-07 31.2 0.1 6.1e-05 23.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP65076.1 - 3.2e-06 27.3 0.8 3.1e-05 24.2 0.1 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEP65076.1 - 4.9e-06 26.0 0.5 0.36 10.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEP65076.1 - 1.1e-05 25.6 0.2 0.0034 17.8 0.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEP65076.1 - 1.4e-05 24.4 0.1 0.086 12.4 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP65076.1 - 0.0038 17.0 0.5 0.052 13.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP65076.1 - 0.019 15.1 0.1 1.1 9.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEP65076.1 - 0.022 14.8 0.1 0.1 12.7 0.1 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEP65076.1 - 0.052 14.0 0.4 0.39 11.2 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 KEP65076.1 - 0.072 13.1 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_8 PF13181.1 KEP65076.1 - 0.13 12.0 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat EamA PF00892.15 KEP65077.1 - 0.21 11.6 13.6 0.059 13.4 7.4 1.5 2 0 0 2 2 2 0 EamA-like transporter family PX PF00787.19 KEP65079.1 - 6.9e-07 29.0 0.7 5.2e-06 26.2 0.5 2.1 1 1 0 1 1 1 1 PX domain Nucleoporin_N PF08801.6 KEP65079.1 - 5.5e-05 22.0 0.0 0.00031 19.6 0.0 2.0 1 1 0 1 1 1 1 Nup133 N terminal like Apc4_WD40 PF12894.2 KEP65079.1 - 0.12 11.9 0.0 13 5.4 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2012 PF09430.5 KEP65080.1 - 1.9e-10 40.6 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 KEP65080.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain PRA1 PF03208.14 KEP65080.1 - 0.12 11.6 0.1 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 PRA1 family protein Peptidase_C26 PF07722.8 KEP65085.1 - 1.2e-18 67.3 0.0 3e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 GATase PF00117.23 KEP65085.1 - 7.4e-10 38.5 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Borrelia_P83 PF05262.6 KEP65086.1 - 1.2 7.2 48.3 1.4 7.0 33.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PLRV_ORF5 PF01690.12 KEP65086.1 - 1.9 7.5 37.7 2.5 7.1 26.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mitofilin PF09731.4 KEP65086.1 - 3.9 6.0 44.3 5.1 5.6 30.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pkinase PF00069.20 KEP65087.1 - 1.6e-35 122.5 0.0 2.3e-20 72.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65087.1 - 5.9e-08 32.0 0.0 0.0054 15.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP65087.1 - 8.9e-06 24.8 0.1 0.071 12.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like YcbB PF08664.5 KEP65088.1 - 1.5 8.5 4.5 4.6 7.0 0.1 2.9 2 1 2 4 4 4 0 YcbB domain Peptidase_C14 PF00656.17 KEP65090.1 - 3.1e-23 82.7 0.0 9.3e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 Caspase domain FAM176 PF14851.1 KEP65091.1 - 0.0045 16.6 1.3 0.44 10.2 0.6 2.7 2 0 0 2 2 2 2 FAM176 family DUF1180 PF06679.7 KEP65091.1 - 0.015 15.2 11.8 0.15 11.9 0.8 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) Met_10 PF02475.11 KEP65092.1 - 3.9e-44 150.6 0.0 7.9e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 KEP65092.1 - 1.7e-05 23.9 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 KEP65092.1 - 0.0026 17.7 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP65092.1 - 0.0028 18.2 0.2 0.09 13.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KEP65092.1 - 0.013 14.6 0.1 0.48 9.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KEP65092.1 - 0.026 14.1 0.0 0.087 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DNA_methylase PF00145.12 KEP65092.1 - 0.069 12.2 0.0 0.069 12.2 0.0 2.6 3 1 0 3 3 3 0 C-5 cytosine-specific DNA methylase Borrelia_rep PF03183.8 KEP65094.1 - 0.52 10.1 18.8 15 5.5 0.4 4.9 4 0 0 4 4 4 0 Borrelia repeat protein BRCA-2_OB1 PF09103.5 KEP65095.1 - 5e-10 39.1 0.0 7.4e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Myosin_head PF00063.16 KEP65097.1 - 2.3e-180 601.0 2.6 3.1e-180 600.6 1.8 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.13 KEP65097.1 - 3.2e-27 94.4 9.3 8.5e-08 32.2 0.0 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP65097.1 - 1.8e-25 87.8 30.0 5.7e-11 41.7 1.0 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 KEP65097.1 - 7.8e-22 74.7 49.5 0.00017 20.9 1.0 8.9 8 0 0 8 8 8 6 IQ calmodulin-binding motif AAA_22 PF13401.1 KEP65097.1 - 0.0065 16.6 0.1 0.03 14.4 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP65097.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KEP65097.1 - 0.018 14.8 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Myosin_N PF02736.14 KEP65097.1 - 0.047 13.3 0.6 0.096 12.3 0.4 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Zeta_toxin PF06414.7 KEP65097.1 - 0.15 11.1 4.1 0.031 13.3 0.2 1.7 2 0 0 2 2 2 0 Zeta toxin WD40 PF00400.27 KEP65098.1 - 1.7e-22 78.3 11.1 0.00044 20.0 0.1 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KEP65098.1 - 0.0057 16.4 0.0 1.1 9.0 0.0 3.3 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 KEP65098.1 - 0.0074 15.7 0.0 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 KEP65098.1 - 0.16 10.6 0.1 6.2 5.4 0.0 2.4 3 0 0 3 3 3 0 Nup133 N terminal like Nop14 PF04147.7 KEP65098.1 - 5.5 4.7 19.6 8.2 4.2 13.6 1.2 1 0 0 1 1 1 0 Nop14-like family Peptidase_C97 PF05903.9 KEP65099.1 - 3.9e-22 78.6 0.0 6e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain APG6 PF04111.7 KEP65100.1 - 4.3 6.2 15.9 0.62 9.0 5.3 2.6 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF605 PF04652.11 KEP65101.1 - 2.7 7.3 12.1 3.5 6.9 8.4 1.1 1 0 0 1 1 1 0 Vta1 like Dmrt1 PF12374.3 KEP65105.1 - 1.2 9.5 8.0 2.2 8.7 5.5 1.6 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 GKAP PF03359.8 KEP65106.1 - 6.6 6.2 8.8 0.76 9.3 1.1 2.1 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein DUF605 PF04652.11 KEP65107.1 - 5.9 6.1 24.8 9.1 5.5 17.2 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KEP65111.1 - 6.9 4.7 13.4 7.6 4.6 9.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MSP1_C PF07462.6 KEP65112.1 - 7.9 4.7 5.0 12 4.1 3.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3437 PF11919.3 KEP65113.1 - 4e-24 84.1 0.1 1.4e-23 82.4 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KEP65113.1 - 0.00072 19.4 6.1 0.69 10.1 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Flavoprotein PF02441.14 KEP65114.1 - 2.5e-41 140.3 0.0 3.7e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein DUF2285 PF10074.4 KEP65114.1 - 0.0091 16.3 0.5 0.017 15.4 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2285) CAF-1_p150 PF11600.3 KEP65114.1 - 5.5 6.3 11.1 10 5.4 7.7 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SET PF00856.23 KEP65115.1 - 6.3e-11 42.8 0.0 4.9e-07 30.1 0.0 2.5 2 1 0 2 2 2 2 SET domain DUF869 PF05911.6 KEP65116.1 - 0.00046 18.5 51.4 0.0067 14.7 18.8 3.1 2 1 1 3 3 3 3 Plant protein of unknown function (DUF869) CCDC155 PF14662.1 KEP65116.1 - 0.00053 19.6 26.6 0.00053 19.6 18.5 4.5 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 TPR_MLP1_2 PF07926.7 KEP65116.1 - 0.0037 16.9 14.3 0.0037 16.9 9.9 4.8 1 1 3 4 4 4 3 TPR/MLP1/MLP2-like protein DUF3919 PF13057.1 KEP65116.1 - 0.0074 15.7 2.7 0.018 14.5 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3919) CALCOCO1 PF07888.6 KEP65116.1 - 0.018 13.3 0.5 0.018 13.3 0.3 3.2 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF972 PF06156.8 KEP65116.1 - 0.019 15.3 60.2 0.14 12.4 2.3 6.4 2 1 3 6 6 6 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 KEP65116.1 - 0.29 8.8 83.1 27 2.2 57.7 3.1 1 1 0 1 1 1 0 Myosin tail Vac_Fusion PF02346.11 KEP65116.1 - 0.76 9.2 18.2 0.53 9.7 0.5 5.2 5 2 2 7 7 7 0 Chordopoxvirus fusion protein ADIP PF11559.3 KEP65116.1 - 2.6 7.9 75.5 0.12 12.2 4.9 5.8 2 1 2 6 6 6 0 Afadin- and alpha -actinin-Binding DUF2312 PF10073.4 KEP65116.1 - 4.7 6.6 26.2 3.5 7.0 0.1 7.1 4 3 4 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2312) Cytochrom_B_N_2 PF13631.1 KEP65117.1 - 0.002 17.9 1.3 0.002 17.9 0.9 1.8 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF2933 PF11666.3 KEP65117.1 - 0.21 11.1 0.1 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) Acyl_transf_3 PF01757.17 KEP65117.1 - 1.1 8.0 8.8 4.6 5.9 6.4 1.7 1 1 1 2 2 2 0 Acyltransferase family DUF3733 PF12534.3 KEP65117.1 - 3.4 7.0 8.0 0.31 10.3 2.3 1.7 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 WBP-1 PF11669.3 KEP65117.1 - 7 6.7 6.9 15 5.7 4.8 1.7 1 1 0 1 1 1 0 WW domain-binding protein 1 DUF3272 PF11676.3 KEP65118.1 - 0.17 11.8 3.4 0.26 11.3 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) XRN_N PF03159.13 KEP65119.1 - 3.2e-91 304.9 0.0 5.8e-91 304.0 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SDA1 PF05285.7 KEP65120.1 - 0.00012 21.5 11.5 0.00018 20.9 8.0 1.3 1 1 0 1 1 1 1 SDA1 DDHD PF02862.12 KEP65120.1 - 1.6 8.4 4.6 2.4 7.9 3.2 1.4 1 1 0 1 1 1 0 DDHD domain Nop14 PF04147.7 KEP65120.1 - 1.7 6.4 30.3 2.4 5.9 21.0 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.6 KEP65120.1 - 4 7.0 17.0 0.78 9.3 8.8 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 CENP-T PF15511.1 KEP65122.1 - 0.83 8.8 33.5 1.1 8.4 23.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 KEP65122.1 - 6.8 5.0 52.1 9.4 4.5 36.1 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KEP65122.1 - 7.3 4.3 57.7 9.7 3.9 40.0 1.0 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S8e PF01201.17 KEP65123.1 - 8.7e-40 135.9 8.0 2.1e-39 134.6 5.5 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e CASP_C PF08172.7 KEP65123.1 - 0.11 11.4 4.2 0.15 11.0 2.9 1.2 1 0 0 1 1 1 0 CASP C terminal RE_Alw26IDE PF09665.5 KEP65125.1 - 1.6 7.3 0.0 2.8 6.5 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) V_ATPase_I PF01496.14 KEP65125.1 - 7.2 4.3 1.5 15 3.2 1.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rrn6 PF10214.4 KEP65125.1 - 8.8 4.2 2.8 16 3.4 1.9 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor APG6 PF04111.7 KEP65126.1 - 0.0029 16.6 11.3 0.0029 16.6 7.8 5.8 3 2 2 5 5 5 3 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KEP65126.1 - 0.061 12.4 20.6 0.89 8.6 2.0 4.4 4 0 0 4 4 4 0 Reovirus sigma C capsid protein Guanylate_kin PF00625.16 KEP65129.1 - 7e-54 182.0 0.0 1.4e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 KEP65129.1 - 7.3e-05 22.8 0.7 0.00021 21.3 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 KEP65129.1 - 0.0014 17.8 0.0 0.0029 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEP65129.1 - 0.0061 17.3 0.2 0.036 14.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP65129.1 - 0.012 15.4 1.3 0.078 12.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEP65129.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KEP65129.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEP65129.1 - 0.03 13.9 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Adeno_IVa2 PF02456.10 KEP65129.1 - 0.062 11.9 0.0 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_18 PF13238.1 KEP65129.1 - 1.7 8.9 5.1 1.3 9.3 0.2 2.9 2 1 1 3 3 3 0 AAA domain TAXi_C PF14541.1 KEP65130.1 - 4.3e-24 84.8 0.0 6.8e-19 67.9 0.0 2.7 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Asp PF00026.18 KEP65130.1 - 3e-22 79.2 0.0 1.7e-15 57.0 0.0 3.4 2 2 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEP65130.1 - 7.7e-14 51.9 0.7 7.7e-14 51.9 0.5 2.9 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Ribosomal_L24e PF01246.15 KEP65133.1 - 2.5e-28 97.7 3.8 5.5e-28 96.6 2.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 KEP65133.1 - 0.0031 17.1 3.5 0.0066 16.0 2.3 1.7 1 1 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif DUF2880 PF11082.3 KEP65133.1 - 0.11 12.3 0.2 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) AAA_23 PF13476.1 KEP65133.1 - 3.5 7.9 8.9 5.1 7.3 6.2 1.3 1 0 0 1 1 1 0 AAA domain Vps35 PF03635.12 KEP65135.1 - 5.7e-260 864.6 0.0 6.6e-260 864.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 PIG-Y PF15159.1 KEP65136.1 - 6.5e-12 45.4 6.1 1e-10 41.6 4.2 2.1 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y AAA_5 PF07728.9 KEP65138.1 - 1.6e-94 313.0 0.0 2.4e-20 72.6 0.0 10.9 11 0 0 11 11 11 9 AAA domain (dynein-related subfamily) AAA PF00004.24 KEP65138.1 - 6.4e-15 55.5 0.0 0.054 13.7 0.0 5.9 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 KEP65138.1 - 1.4e-11 44.1 0.0 7e-05 22.4 0.0 5.9 7 0 0 7 7 6 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP65138.1 - 9.2e-11 42.0 0.0 0.05 13.7 0.0 6.8 5 1 0 5 5 5 2 AAA domain Mg_chelatase PF01078.16 KEP65138.1 - 7e-10 38.4 0.9 0.098 11.7 0.0 6.3 6 1 1 7 7 6 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KEP65138.1 - 7e-08 31.8 0.4 0.61 9.6 0.0 5.3 5 0 0 5 5 5 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KEP65138.1 - 1.3e-07 31.8 31.8 0.017 15.1 0.0 8.5 9 0 0 9 9 7 4 AAA ATPase domain ABC_tran PF00005.22 KEP65138.1 - 1.6e-07 31.6 0.6 0.18 12.1 0.0 5.1 5 0 0 5 5 5 2 ABC transporter AAA_17 PF13207.1 KEP65138.1 - 3.1e-06 27.9 0.1 3.9 8.3 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.1 KEP65138.1 - 1.1e-05 25.3 0.0 0.046 13.6 0.0 5.4 7 0 0 7 7 6 1 AAA domain Sigma54_activ_2 PF14532.1 KEP65138.1 - 3.1e-05 24.0 3.9 0.38 10.8 0.0 6.5 7 0 0 7 7 6 1 Sigma-54 interaction domain UPF0079 PF02367.12 KEP65138.1 - 0.00013 21.6 1.0 18 5.0 0.0 4.5 4 0 0 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KEP65138.1 - 0.00016 21.3 2.1 0.84 9.2 0.0 4.4 4 0 0 4 4 4 1 NACHT domain Sigma54_activat PF00158.21 KEP65138.1 - 0.00064 19.2 0.3 6.5 6.1 0.0 5.8 7 0 0 7 7 6 0 Sigma-54 interaction domain Miro PF08477.8 KEP65138.1 - 0.00065 20.1 0.1 4.9 7.6 0.0 3.8 4 0 0 4 4 3 1 Miro-like protein T2SE PF00437.15 KEP65138.1 - 0.0011 17.8 0.0 0.55 9.0 0.0 4.3 5 0 0 5 5 5 1 Type II/IV secretion system protein Dynein_heavy PF03028.10 KEP65138.1 - 0.0028 15.7 0.0 0.1 10.6 0.0 2.9 4 0 0 4 4 4 1 Dynein heavy chain and region D6 of dynein motor Rad17 PF03215.10 KEP65138.1 - 0.056 12.1 0.1 3.3 6.2 0.0 3.1 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KEP65138.1 - 0.1 12.7 0.2 80 3.4 0.0 4.3 5 0 0 5 5 4 0 RNA helicase MobB PF03205.9 KEP65138.1 - 0.32 10.6 1.6 37 4.0 0.0 4.4 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KEP65138.1 - 1.2 8.5 0.3 30 4.0 0.0 3.1 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_PrkA PF08298.6 KEP65138.1 - 3.4 6.2 0.0 80 1.7 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_21 PF13304.1 KEP65138.1 - 4.1 7.2 0.0 20 5.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.2 KEP65138.1 - 4.5 6.2 0.1 49 2.8 0.0 2.3 3 0 0 3 3 2 0 P-loop containing dynein motor region D3 Ras PF00071.17 KEP65138.1 - 6.4 6.1 0.6 58 3.0 0.1 2.3 2 0 0 2 2 2 0 Ras family KaiC PF06745.8 KEP65138.1 - 9.4 5.2 0.1 60 2.6 0.0 2.3 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 KEP65138.1 - 9.4 5.8 0.0 37 3.8 0.0 2.0 2 0 0 2 2 1 0 Archaeal ATPase AAA_16 PF13191.1 KEP65139.1 - 9.6e-07 28.9 0.0 3.8e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KEP65139.1 - 0.00095 18.8 0.0 0.0031 17.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEP65139.1 - 0.0024 17.9 0.0 0.0099 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEP65139.1 - 0.0088 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEP65139.1 - 0.011 16.5 0.0 0.021 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEP65139.1 - 0.016 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KEP65139.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 KEP65139.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KEP65139.1 - 0.021 14.5 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 KEP65139.1 - 0.043 13.3 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEP65139.1 - 0.076 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEP65139.1 - 0.087 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEP65139.1 - 0.095 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KEP65139.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin WD40 PF00400.27 KEP65140.1 - 5.5e-17 60.9 11.7 1.4e-07 31.1 0.2 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat 6PGD PF00393.14 KEP65141.1 - 1e-93 313.7 0.4 2.6e-93 312.4 0.2 1.6 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KEP65141.1 - 4.9e-33 114.2 0.0 7.9e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KEP65141.1 - 0.0054 16.3 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YagB_YeeU_YfjZ PF06154.6 KEP65141.1 - 0.034 14.3 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 YagB/YeeU/YfjZ family NAD_binding_11 PF14833.1 KEP65141.1 - 0.16 12.0 0.4 0.45 10.5 0.1 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase HisKA PF00512.20 KEP65142.1 - 0.027 14.4 7.8 0.14 12.2 0.2 3.8 3 1 1 4 4 4 0 His Kinase A (phospho-acceptor) domain DUF1664 PF07889.7 KEP65142.1 - 0.3 10.9 3.1 1.9 8.2 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Fe_hyd_lg_C PF02906.9 KEP65143.1 - 3.2e-54 184.1 0.0 5.3e-25 88.2 0.0 3.9 3 1 0 3 3 3 3 Iron only hydrogenase large subunit, C-terminal domain CHCH PF06747.8 KEP65144.1 - 0.17 11.8 1.7 12 5.9 0.1 2.7 2 0 0 2 2 2 0 CHCH domain Mito_carr PF00153.22 KEP65146.1 - 3.7e-50 167.6 7.1 1.2e-23 82.5 0.3 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Amino_oxidase PF01593.19 KEP65148.1 - 7.1e-38 130.8 5.1 2.9e-29 102.4 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEP65148.1 - 3.9e-13 49.2 0.2 1.8e-12 47.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KEP65148.1 - 3e-06 26.5 0.5 5.6e-06 25.6 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEP65148.1 - 1.3e-05 24.4 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KEP65148.1 - 1.6e-05 23.9 0.9 3.8e-05 22.7 0.6 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEP65148.1 - 1.7e-05 23.8 1.0 3e-05 23.0 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEP65148.1 - 5.5e-05 23.4 0.1 0.00016 22.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEP65148.1 - 0.00024 21.0 0.1 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEP65148.1 - 0.0012 17.8 0.4 0.0019 17.1 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KEP65148.1 - 0.0012 18.9 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEP65148.1 - 0.0028 16.2 0.2 0.004 15.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KEP65148.1 - 0.043 12.7 0.1 0.075 11.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KEP65148.1 - 0.29 10.6 0.3 0.71 9.4 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 KEP65149.1 - 7.3e-76 254.7 0.0 1.1e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65149.1 - 1.9e-34 118.9 0.0 2.7e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP65149.1 - 1.6e-27 92.6 11.4 7.1e-08 31.2 1.9 5.0 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 KEP65149.1 - 3.8e-26 90.9 0.9 3.4e-13 49.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEP65149.1 - 8.4e-21 73.3 5.6 4.5e-06 26.1 0.2 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KEP65149.1 - 9.2e-21 71.8 6.5 0.00019 21.0 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEP65149.1 - 3.9e-18 63.8 11.7 6.6e-05 22.0 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_9 PF14658.1 KEP65149.1 - 4.7e-05 23.2 0.1 2.1 8.3 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 KEP65149.1 - 4.9e-05 23.0 0.4 0.48 10.1 0.0 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 KEP65149.1 - 6.4e-05 22.0 0.0 0.00021 20.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEP65149.1 - 0.0025 16.9 0.0 0.0054 15.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP65149.1 - 0.017 14.8 0.0 0.044 13.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.4 KEP65149.1 - 0.024 14.6 0.0 9.5 6.2 0.0 3.2 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.1 KEP65149.1 - 0.036 14.3 0.8 1.1 9.5 0.0 2.8 2 1 1 3 3 3 0 Toprim-like Choline_kinase PF01633.15 KEP65149.1 - 0.054 13.0 0.0 0.32 10.5 0.0 2.1 3 0 0 3 3 3 0 Choline/ethanolamine kinase Toprim PF01751.17 KEP65149.1 - 0.46 10.4 2.0 3 7.8 0.0 3.0 4 0 0 4 4 4 0 Toprim domain ECH PF00378.15 KEP65150.1 - 8.6e-31 106.9 0.0 1e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KEP65150.1 - 0.0046 16.7 0.1 0.76 9.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 DUF4590 PF15257.1 KEP65150.1 - 0.12 12.1 0.0 0.39 10.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4590) ELO PF01151.13 KEP65151.1 - 2.7e-47 161.2 16.7 3.5e-47 160.8 11.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4191 PF13829.1 KEP65151.1 - 0.24 10.4 0.5 2.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Phage_Mu_Gam PF07352.7 KEP65152.1 - 0.22 11.0 3.5 1.3 8.4 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein ATP-synt_B PF00430.13 KEP65152.1 - 0.99 9.2 10.6 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Tropomyosin_1 PF12718.2 KEP65152.1 - 4.8 7.0 11.3 0.46 10.3 4.1 1.9 2 0 0 2 2 2 0 Tropomyosin like DUF342 PF03961.8 KEP65152.1 - 7.9 4.7 6.7 0.86 7.9 1.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TPR_19 PF14559.1 KEP65153.1 - 1.8e-25 89.0 47.3 5e-05 23.5 0.1 11.8 8 3 3 13 13 13 7 Tetratricopeptide repeat TPR_11 PF13414.1 KEP65153.1 - 8.9e-23 79.7 30.4 1.4e-08 34.2 0.6 9.2 7 2 5 12 12 11 7 TPR repeat TPR_16 PF13432.1 KEP65153.1 - 1.2e-22 79.9 57.3 8.1e-07 29.5 0.2 12.0 10 2 2 13 13 13 8 Tetratricopeptide repeat TPR_14 PF13428.1 KEP65153.1 - 5e-21 73.2 52.5 0.013 16.1 0.4 16.9 8 5 8 17 17 16 7 Tetratricopeptide repeat TPR_12 PF13424.1 KEP65153.1 - 7.1e-16 57.9 41.2 0.00073 19.4 1.2 11.3 11 2 1 12 12 12 6 Tetratricopeptide repeat TPR_2 PF07719.12 KEP65153.1 - 1.8e-15 55.4 49.6 0.0034 17.1 1.5 14.4 17 0 0 17 17 15 6 Tetratricopeptide repeat TPR_8 PF13181.1 KEP65153.1 - 7.9e-15 53.4 7.8 0.04 13.6 0.1 9.4 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEP65153.1 - 7.4e-14 50.6 20.5 0.0031 17.0 0.6 10.7 11 1 0 11 11 10 4 Tetratricopeptide repeat Apc3 PF12895.2 KEP65153.1 - 2.5e-10 40.3 19.8 3.6e-06 27.0 0.1 8.3 7 2 2 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEP65153.1 - 2e-08 33.9 31.4 0.0038 17.0 0.6 7.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEP65153.1 - 8.7e-07 28.2 29.0 0.22 11.4 0.1 10.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEP65153.1 - 4.7e-06 26.3 12.4 0.99 9.7 0.0 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat HeLo PF14479.1 KEP65153.1 - 0.00079 19.2 0.7 0.0021 17.8 0.5 1.7 1 0 0 1 1 1 1 Prion-inhibition and propagation TPR_6 PF13174.1 KEP65153.1 - 0.11 13.0 33.2 22 5.8 0.1 12.1 15 1 0 15 15 13 0 Tetratricopeptide repeat TPR_21 PF09976.4 KEP65153.1 - 5 7.0 28.2 1.4 8.8 0.6 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Ribosomal_S14 PF00253.16 KEP65154.1 - 6.7e-17 60.6 5.1 9.7e-17 60.1 3.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-RING_5 PF14634.1 KEP65154.1 - 0.87 9.3 4.2 2.8 7.7 0.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Ribosomal_S7 PF00177.16 KEP65155.1 - 2.3e-43 147.3 1.5 2.6e-43 147.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-B_box PF00643.19 KEP65156.1 - 1.6e-10 40.7 8.6 7.9e-05 22.4 1.3 2.4 2 0 0 2 2 2 2 B-box zinc finger CAP_N PF01213.14 KEP65157.1 - 0.06 12.6 0.2 0.084 12.1 0.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DHDPS PF00701.17 KEP65158.1 - 2e-89 299.0 0.0 2.3e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.17 KEP65158.1 - 0.016 14.9 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 PA domain ADH_zinc_N PF00107.21 KEP65158.1 - 0.085 12.4 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Proteasome PF00227.21 KEP65159.1 - 5.3e-38 130.2 0.1 8.2e-38 129.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEP65159.1 - 4e-15 54.7 0.0 7.5e-15 53.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature amfpi-1 PF12190.3 KEP65159.1 - 0.04 14.4 0.4 9.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Fungal protease inhibitor NUDIX PF00293.23 KEP65160.1 - 2e-05 24.2 0.1 7e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Kinase-like PF14531.1 KEP65162.1 - 1.7e-22 79.7 0.0 3.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP65162.1 - 3.3e-19 69.0 0.0 5.4e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65162.1 - 4.4e-08 32.5 0.0 6.3e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEP65163.1 - 1.9e-21 76.4 0.0 3.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEP65163.1 - 1e-20 73.9 0.0 2.6e-20 72.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KEP65163.1 - 2.1e-08 33.5 0.0 4.2e-08 32.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase zf-CCCH PF00642.19 KEP65164.1 - 7.2e-14 51.0 15.5 8.5e-05 22.1 0.4 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 KEP65164.1 - 0.0066 15.8 7.7 0.019 14.4 1.4 2.8 2 0 0 2 2 2 2 Putative zinc-finger domain V-SNARE_C PF12352.3 KEP65165.1 - 2e-06 27.7 2.7 2e-06 27.7 1.8 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEP65165.1 - 0.016 14.9 1.8 0.024 14.3 0.2 2.0 2 0 0 2 2 2 0 Sec20 cNMP_binding PF00027.24 KEP65166.1 - 3.2e-49 164.7 0.0 1.7e-24 85.4 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain YflT PF11181.3 KEP65166.1 - 0.0056 16.8 0.1 1.3 9.2 0.0 2.6 2 0 0 2 2 2 2 Heat induced stress protein YflT DEAD PF00270.24 KEP65168.1 - 1.6e-11 44.0 0.0 3.5e-10 39.6 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP65168.1 - 2.6e-10 39.9 0.0 5.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain COG7 PF10191.4 KEP65169.1 - 0.0043 15.0 0.1 0.0043 15.0 0.1 1.9 3 0 0 3 3 3 1 Golgi complex component 7 (COG7) LXG PF04740.7 KEP65169.1 - 0.021 14.6 0.1 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily Glyco_hydro_63 PF03200.11 KEP65170.1 - 5.7e-68 229.5 0.0 1.2e-36 125.9 0.0 6.0 5 1 0 5 5 5 4 Mannosyl oligosaccharide glucosidase GIDA PF01134.17 KEP65171.1 - 1.3e-115 386.4 0.0 2.2e-67 227.6 0.0 3.1 3 0 0 3 3 3 3 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KEP65171.1 - 3e-09 36.8 0.0 7.3e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 KEP65171.1 - 2.7e-05 23.4 2.5 6.2e-05 22.2 1.7 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEP65171.1 - 0.00017 21.5 0.1 0.0003 20.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEP65171.1 - 0.00025 20.0 2.0 0.00052 18.9 1.4 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEP65171.1 - 0.028 12.8 0.5 0.37 9.2 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KEP65171.1 - 0.21 10.6 0.1 0.35 9.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family AMMECR1 PF01871.12 KEP65172.1 - 2.6e-35 121.0 0.0 3.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 DUF2246 PF10229.4 KEP65174.1 - 0.027 13.7 0.0 0.029 13.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) PDEase_I PF00233.14 KEP65175.1 - 7.2e-55 186.3 0.0 1.1e-54 185.7 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KEP65175.1 - 0.006 16.5 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 HD domain DUF3722 PF12519.3 KEP65175.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) tRNA-synt_1c PF00749.16 KEP65176.1 - 2.5e-64 216.9 0.0 1.8e-51 174.6 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain PIGA PF08288.7 KEP65177.1 - 4.6e-41 139.1 2.2 5.4e-41 138.8 0.3 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KEP65177.1 - 6.5e-27 94.0 0.0 1e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KEP65177.1 - 1.8e-19 70.4 0.9 4.4e-19 69.1 0.7 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KEP65177.1 - 7.2e-16 58.4 1.3 1.3e-15 57.5 0.9 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KEP65177.1 - 6.7e-13 48.9 0.0 1.9e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 KEP65177.1 - 3.8e-08 33.2 0.1 6.8e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KEP65177.1 - 0.0018 18.5 0.2 0.0069 16.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 zf-HC5HC2H_2 PF13832.1 KEP65178.1 - 0.00085 19.2 61.8 0.039 13.9 0.2 11.2 12 0 0 12 12 12 4 PHD-zinc-finger like domain PHD_2 PF13831.1 KEP65178.1 - 0.0013 17.9 3.2 0.0013 17.9 2.2 7.4 8 0 0 8 8 8 5 PHD-finger PHD PF00628.24 KEP65178.1 - 0.0015 18.1 0.9 0.0015 18.1 0.6 9.2 11 0 0 11 11 11 2 PHD-finger Baculo_ME53 PF06061.6 KEP65178.1 - 3.5 6.5 0.2 8.4 5.2 0.2 1.5 1 0 0 1 1 1 0 Baculoviridae ME53 CUE PF02845.11 KEP65179.1 - 7.8e-09 34.8 0.1 0.0002 20.7 0.0 2.4 2 0 0 2 2 2 2 CUE domain C2 PF00168.25 KEP65179.1 - 2.5e-05 24.0 0.0 9.8e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 C2 domain Pro_isomerase PF00160.16 KEP65180.1 - 2.6e-33 115.4 0.0 6.2e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NfeD PF01957.13 KEP65181.1 - 0.033 14.3 8.7 0.042 13.9 2.4 2.8 1 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding TctB PF07331.6 KEP65181.1 - 4.5 6.9 15.2 23 4.5 10.5 2.0 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family CbiQ PF02361.11 KEP65181.1 - 8.8 5.8 9.6 0.94 8.9 0.6 2.2 2 0 0 2 2 2 0 Cobalt transport protein CHCH PF06747.8 KEP65184.1 - 0.0023 17.8 0.2 0.0034 17.2 0.1 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KEP65184.1 - 0.1 12.6 0.3 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KEP65184.1 - 0.12 12.3 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb V_ATPase_I PF01496.14 KEP65187.1 - 3.9 5.2 8.4 5.6 4.6 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ubiquitin PF00240.18 KEP65189.1 - 4.4e-10 38.8 0.0 1.2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KEP65189.1 - 0.0003 20.4 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEP65189.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain PARP PF00644.15 KEP65190.1 - 0.0043 16.5 0.0 0.0061 16.0 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-HIT PF04438.11 KEP65191.1 - 5.9e-08 32.2 13.1 1.1e-07 31.3 9.1 1.4 1 0 0 1 1 1 1 HIT zinc finger BMP2K_C PF15282.1 KEP65191.1 - 0.47 10.5 5.3 1 9.4 0.2 3.0 2 1 1 3 3 3 0 BMP-2-inducible protein kinase C-terminus PI31_Prot_C PF08577.6 KEP65192.1 - 4.8e-07 30.3 13.6 4.8e-07 30.3 9.4 2.8 3 0 0 3 3 3 1 PI31 proteasome regulator Euplotes_phero PF05842.6 KEP65194.1 - 1.6 9.0 1.4 5 7.4 1.0 1.8 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Rhomboid PF01694.17 KEP65196.1 - 4.4e-13 49.4 5.2 5.2e-13 49.2 2.4 1.8 1 1 1 2 2 2 1 Rhomboid family DER1 PF04511.10 KEP65196.1 - 6.6e-05 22.5 2.2 8.7e-05 22.1 1.5 1.3 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 KEP65196.1 - 0.03 14.6 2.3 0.03 14.6 1.6 1.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DUF3377 PF11857.3 KEP65196.1 - 0.29 10.7 1.5 2.6 7.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) DUF3792 PF12670.2 KEP65196.1 - 0.91 9.4 5.4 1.5 8.6 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) NifU PF01106.12 KEP65198.1 - 5.9e-18 64.4 0.0 1.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 KEP65198.1 - 1.6e-15 56.4 0.0 3.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal DUF1032 PF06278.6 KEP65200.1 - 1.1e-09 37.4 0.1 0.016 13.7 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF1032) Arf PF00025.16 KEP65201.1 - 8e-69 230.3 0.1 9e-69 230.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEP65201.1 - 1.9e-11 43.3 5.0 3.2e-07 29.4 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KEP65201.1 - 2.8e-10 39.8 0.0 3.3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEP65201.1 - 3.1e-09 36.3 0.0 3.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEP65201.1 - 6.6e-08 31.9 0.0 9.3e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KEP65201.1 - 1.9e-06 28.3 0.0 2.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KEP65201.1 - 4.1e-06 26.3 0.0 0.0001 21.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEP65201.1 - 5.9e-06 26.2 0.0 8.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PPK2 PF03976.9 KEP65201.1 - 0.099 11.9 0.1 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) CENP-F_leu_zip PF10473.4 KEP65202.1 - 0.00044 20.1 4.3 0.00044 20.1 3.0 2.5 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 KEP65202.1 - 0.005 14.7 9.3 0.032 12.0 2.6 2.3 1 1 1 2 2 2 2 HOOK protein Filament PF00038.16 KEP65202.1 - 0.0055 16.2 3.8 0.0055 16.2 2.6 2.6 1 1 1 2 2 2 1 Intermediate filament protein SlyX PF04102.7 KEP65202.1 - 0.022 15.1 1.2 0.022 15.1 0.8 3.9 2 1 2 4 4 4 0 SlyX DUF972 PF06156.8 KEP65202.1 - 0.034 14.5 8.1 0.068 13.5 1.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) TMCO5 PF14992.1 KEP65202.1 - 0.034 13.2 2.6 0.073 12.1 1.8 1.6 1 0 0 1 1 1 0 TMCO5 family TEX13 PF15186.1 KEP65202.1 - 0.036 13.6 2.5 0.094 12.2 0.6 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family BLOC1_2 PF10046.4 KEP65202.1 - 0.087 12.9 1.5 0.31 11.1 0.2 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.7 KEP65202.1 - 0.12 12.5 7.0 1.5 9.0 1.6 3.3 2 2 1 3 3 3 0 Centromere protein H (CENP-H) Reo_sigmaC PF04582.7 KEP65202.1 - 0.15 11.2 2.9 0.26 10.4 1.2 1.9 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 KEP65202.1 - 0.18 11.3 6.8 3 7.3 0.3 2.8 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 KEP65202.1 - 0.19 10.7 7.1 0.46 9.4 4.7 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 KEP65202.1 - 0.23 11.1 0.9 2.2 7.9 0.6 2.2 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HR1 PF02185.11 KEP65202.1 - 0.26 11.0 10.3 0.38 10.5 0.4 3.4 3 0 0 3 3 3 0 Hr1 repeat HALZ PF02183.13 KEP65202.1 - 0.27 10.9 14.6 0.083 12.6 1.1 4.5 3 1 0 4 4 4 0 Homeobox associated leucine zipper CCDC155 PF14662.1 KEP65202.1 - 0.27 10.8 14.5 0.39 10.2 2.7 2.6 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 GAS PF13851.1 KEP65202.1 - 0.32 10.1 6.6 13 4.9 4.9 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 KEP65202.1 - 0.35 10.8 10.6 0.75 9.8 0.1 3.8 3 1 1 4 4 3 0 bZIP transcription factor K-box PF01486.12 KEP65202.1 - 1 9.1 7.7 6.2 6.6 0.2 3.4 2 1 0 3 3 3 0 K-box region Mod_r PF07200.8 KEP65202.1 - 1.2 9.0 12.5 0.086 12.7 1.2 2.5 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.6 KEP65202.1 - 1.3 7.6 7.2 0.5 8.9 1.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF904 PF06005.7 KEP65202.1 - 1.5 9.1 10.5 2.6e+03 -1.3 7.3 3.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Spectrin PF00435.16 KEP65202.1 - 1.8 8.9 8.5 7.8 6.8 2.8 2.6 2 1 1 3 3 2 0 Spectrin repeat G-gamma PF00631.17 KEP65202.1 - 2.5 7.9 6.3 11 5.8 0.2 3.1 3 0 0 3 3 3 0 GGL domain FlxA PF14282.1 KEP65202.1 - 6.1 6.8 8.1 5.3 7.0 2.0 3.1 2 1 1 3 3 3 0 FlxA-like protein Pkinase PF00069.20 KEP65203.1 - 5.7e-36 123.9 0.0 1.9e-18 66.5 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65203.1 - 4.3e-13 48.9 0.0 3.8e-10 39.2 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KEP65203.1 - 0.00084 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_7 PF13499.1 KEP65203.1 - 0.0032 17.5 0.0 0.24 11.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair Kinase-like PF14531.1 KEP65203.1 - 0.0034 16.3 0.0 0.73 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like EF-hand_8 PF13833.1 KEP65203.1 - 0.0087 15.6 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Kdo PF06293.9 KEP65203.1 - 0.025 13.6 0.0 0.045 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.1 KEP65203.1 - 0.21 11.5 0.0 27 4.7 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain KH_1 PF00013.24 KEP65204.1 - 1.7e-18 65.9 0.1 4.8e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KEP65204.1 - 2.7e-11 42.8 0.1 1.7e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 KEP65204.1 - 0.00089 18.7 0.6 0.24 10.9 0.1 2.5 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 KEP65204.1 - 0.16 11.6 1.7 12 5.6 0.1 2.6 2 0 0 2 2 2 0 KH domain KH_5 PF13184.1 KEP65204.1 - 2.3 8.0 5.2 38 4.1 0.1 3.1 3 0 0 3 3 3 0 NusA-like KH domain Choline_transpo PF04515.7 KEP65205.1 - 8.1e-41 139.8 26.2 8.1e-41 139.8 18.2 1.6 2 0 0 2 2 2 1 Plasma-membrane choline transporter V_ATPase_I PF01496.14 KEP65205.1 - 2.6 5.7 2.2 4 5.1 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA PF00004.24 KEP65206.1 - 1.5e-15 57.5 0.1 5.5e-15 55.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KEP65206.1 - 1.7e-14 53.7 0.0 5.5e-14 52.1 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KEP65206.1 - 8.3e-14 51.3 0.0 2.7e-13 49.6 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KEP65206.1 - 3e-10 39.3 0.0 1e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KEP65206.1 - 4.4e-09 36.5 0.0 1.1e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP65206.1 - 2.5e-06 27.6 0.9 8.5e-06 25.8 0.1 2.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 KEP65206.1 - 7e-06 25.7 0.1 1.5e-05 24.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP65206.1 - 2.7e-05 23.8 0.1 9.5e-05 22.0 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 KEP65206.1 - 5.4e-05 22.8 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEP65206.1 - 0.00015 20.9 0.0 0.00038 19.5 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KEP65206.1 - 0.00015 21.6 0.0 0.0021 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KEP65206.1 - 0.00025 20.1 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.8 KEP65206.1 - 0.0011 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.8 KEP65206.1 - 0.0016 17.4 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 KEP65206.1 - 0.0017 18.0 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase DEAD PF00270.24 KEP65206.1 - 0.0039 16.7 0.1 0.032 13.7 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEP65206.1 - 0.0041 16.9 0.1 0.02 14.7 0.1 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 KEP65206.1 - 0.0045 16.7 0.1 0.018 14.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Torsin PF06309.6 KEP65206.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_3 PF07726.6 KEP65206.1 - 0.013 15.1 0.1 0.73 9.4 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEP65206.1 - 0.013 14.8 0.1 0.049 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 KEP65206.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 KEP65206.1 - 0.017 14.5 0.2 0.16 11.3 0.1 2.2 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KEP65206.1 - 0.021 14.7 0.4 0.055 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KEP65206.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 KEP65206.1 - 0.026 13.7 0.2 0.066 12.3 0.1 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KEP65206.1 - 0.042 14.6 0.0 0.23 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Semenogelin PF05474.6 KEP65206.1 - 0.054 11.7 0.1 0.073 11.3 0.1 1.1 1 0 0 1 1 1 0 Semenogelin FtsK_SpoIIIE PF01580.13 KEP65206.1 - 0.056 12.9 0.9 0.35 10.3 0.0 2.5 2 1 1 3 3 3 0 FtsK/SpoIIIE family SRP54 PF00448.17 KEP65206.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TIP49 PF06068.8 KEP65206.1 - 0.075 11.7 0.0 0.27 9.9 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus zf-PHD-like PF15446.1 KEP65206.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain AAA_28 PF13521.1 KEP65206.1 - 0.14 12.1 0.3 0.34 10.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Holin_LLH PF09682.5 KEP65206.1 - 0.16 12.0 0.4 0.62 10.2 0.1 2.2 2 1 1 3 3 2 0 Phage holin protein (Holin_LLH) zf-RING_2 PF13639.1 KEP65208.1 - 4.2e-05 23.2 1.7 4.2e-05 23.2 1.2 3.4 3 0 0 3 3 3 1 Ring finger domain IBR PF01485.16 KEP65208.1 - 7.4e-05 22.5 14.0 0.0002 21.1 1.9 3.1 3 0 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 KEP65208.1 - 0.0059 16.2 0.8 0.0059 16.2 0.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP65208.1 - 0.009 16.0 1.7 0.009 16.0 1.2 3.6 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP65208.1 - 0.018 15.1 0.8 0.043 13.9 0.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger GAGA PF09237.6 KEP65208.1 - 0.028 14.0 0.4 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 GAGA factor DUF3597 PF12200.3 KEP65208.1 - 6.5 7.1 6.5 3.6 8.0 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) zf-C3HC4_4 PF15227.1 KEP65208.1 - 8.7 6.3 16.2 5.8 6.8 1.3 3.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Clathrin_lg_ch PF01086.12 KEP65210.1 - 1.9e-10 41.0 15.0 8.8e-10 38.8 10.4 2.0 1 1 0 1 1 1 1 Clathrin light chain MDMPI_N PF11716.3 KEP65210.1 - 0.73 10.2 6.5 0.15 12.4 2.0 1.7 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain WD40 PF00400.27 KEP65213.1 - 2.6e-14 52.4 13.2 0.0057 16.4 0.1 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 KEP65213.1 - 2.3e-11 43.5 0.1 0.00034 20.1 0.1 4.0 3 1 0 3 3 3 3 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEP65213.1 - 6.3e-05 22.6 0.0 0.0021 17.7 0.0 2.6 1 1 0 1 1 1 1 Peptidase dimerisation domain GATase_6 PF13522.1 KEP65213.1 - 0.001 19.0 0.0 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain BBS2_Mid PF14783.1 KEP65213.1 - 0.18 11.5 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region GATase_4 PF13230.1 KEP65213.1 - 0.52 8.9 0.3 29 3.1 0.0 2.9 4 0 0 4 4 4 0 Glutamine amidotransferases class-II Relaxase PF03432.9 KEP65214.1 - 7.3 5.8 9.3 0.27 10.5 2.1 1.7 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain ATP11 PF06644.6 KEP65215.1 - 2.6e-05 23.8 0.0 3.3e-05 23.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Sec1 PF00995.18 KEP65216.1 - 2.6e-113 379.6 0.0 3e-113 379.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family YGGT PF02325.12 KEP65217.1 - 3e-12 46.3 1.2 6.7e-12 45.1 0.8 1.6 1 0 0 1 1 1 1 YGGT family CLP_protease PF00574.18 KEP65218.1 - 1.8e-13 50.5 0.0 1.1e-07 31.6 0.1 3.1 3 0 0 3 3 3 3 Clp protease Med3 PF11593.3 KEP65219.1 - 3.7 6.6 4.3 4.4 6.4 3.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SAG PF04092.8 KEP65222.1 - 0.0036 17.6 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 SRS domain Mo25 PF08569.6 KEP65223.1 - 7.3 5.5 0.0 15 4.5 0.0 1.4 1 0 0 1 1 1 0 Mo25-like HHH PF00633.18 KEP65225.1 - 0.0025 17.3 0.0 0.0073 15.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif RabGAP-TBC PF00566.13 KEP65226.1 - 1.6e-43 148.6 2.2 2.2e-43 148.2 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain VPS28 PF03997.7 KEP65226.1 - 0.15 11.6 0.2 0.41 10.2 0.1 1.7 1 0 0 1 1 1 0 VPS28 protein Ribosomal_S19 PF00203.16 KEP65227.1 - 9.7e-27 92.4 0.2 1.8e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S19 GMC_oxred_N PF00732.14 KEP65227.1 - 9e-25 87.4 0.3 9.7e-12 44.6 0.0 3.3 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KEP65227.1 - 1.6e-18 67.4 0.0 4.2e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 KEP65227.1 - 0.00042 19.3 0.0 0.0007 18.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEP65227.1 - 0.0022 18.3 0.1 0.03 14.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEP65227.1 - 0.0054 15.8 0.1 0.0087 15.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 KEP65227.1 - 0.0072 15.7 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KEP65227.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 KEP65227.1 - 0.017 15.1 0.1 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEP65227.1 - 0.024 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KEP65227.1 - 0.033 12.6 0.0 0.053 11.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KEP65227.1 - 0.042 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GDI PF00996.13 KEP65227.1 - 0.12 10.6 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor LRR_6 PF13516.1 KEP65228.1 - 6.1e-25 84.4 15.1 8.7e-06 25.2 0.1 8.8 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.2 KEP65228.1 - 1.9e-12 46.4 13.5 0.011 15.3 0.1 5.0 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEP65228.1 - 1.1e-06 27.8 10.7 2.9 8.2 0.0 7.8 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.1 KEP65228.1 - 1.2e-05 24.9 17.1 0.35 10.6 1.1 4.7 2 2 1 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 KEP65228.1 - 7.6e-05 22.2 15.9 24 5.6 0.0 7.9 8 0 0 8 8 8 1 Leucine rich repeat LRR_2 PF07723.8 KEP65228.1 - 0.05 14.1 3.7 72 4.1 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat FH2 PF02181.18 KEP65229.1 - 7.5e-27 94.1 0.0 1.3e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain DsbC PF11412.3 KEP65229.1 - 0.2 11.4 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC zf-CCCH PF00642.19 KEP65232.1 - 6.6e-05 22.4 9.3 6.6e-05 22.4 6.4 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEP65232.1 - 5.3 7.2 8.5 6.8 6.8 2.1 2.9 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type LSM PF01423.17 KEP65233.1 - 9e-20 70.0 0.0 1.1e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEP65233.1 - 0.0026 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RAP PF08373.5 KEP65234.1 - 2.9e-06 26.9 0.7 5.3e-06 26.1 0.2 1.7 2 0 0 2 2 2 1 RAP domain KRAP_IP3R_bind PF14722.1 KEP65234.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain XPC-binding PF09280.6 KEP65237.1 - 0.19 11.2 2.1 6.3 6.3 0.0 3.6 4 0 0 4 4 4 0 XPC-binding domain FinO_N PF12602.3 KEP65238.1 - 0.061 13.6 0.0 17 5.8 0.0 2.2 2 0 0 2 2 2 0 Fertility inhibition protein N terminal DUF3621 PF12285.3 KEP65238.1 - 0.19 11.9 2.6 1.1e+02 3.1 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3621) Peptidase_M20 PF01546.23 KEP65242.1 - 1.8e-34 118.9 0.5 2.5e-34 118.4 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEP65242.1 - 7.9e-08 32.0 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-DHHC PF01529.15 KEP65244.1 - 6.7e-40 136.3 4.2 1.2e-39 135.4 2.9 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF373 PF04123.8 KEP65244.1 - 0.63 9.0 1.5 1.1 8.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ninjurin PF04923.7 KEP65246.1 - 0.74 9.5 3.9 0.59 9.8 0.1 2.4 1 1 1 2 2 2 0 Ninjurin DUF4033 PF13225.1 KEP65247.1 - 0.27 10.8 7.3 0.46 10.1 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4033) SBF2 PF12335.3 KEP65249.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Myotubularin protein FAST_1 PF06743.10 KEP65249.1 - 0.034 13.8 0.1 0.98 9.1 0.0 2.6 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 ABC1 PF03109.11 KEP65251.1 - 4e-37 126.8 0.1 8.6e-37 125.7 0.1 1.6 1 0 0 1 1 1 1 ABC1 family ATP_bind_1 PF03029.12 KEP65252.1 - 6e-72 242.0 0.0 1.4e-65 221.1 0.0 2.0 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KEP65252.1 - 2.6e-05 25.0 0.4 7.3e-05 23.5 0.3 2.1 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.12 KEP65252.1 - 0.003 17.3 0.0 0.0062 16.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KEP65252.1 - 0.004 16.6 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 KEP65252.1 - 0.0042 17.4 0.0 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEP65252.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP65252.1 - 0.006 16.4 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEP65252.1 - 0.028 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KEP65252.1 - 0.03 14.4 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 KEP65252.1 - 0.039 13.4 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 KEP65252.1 - 0.05 13.3 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activat PF00158.21 KEP65252.1 - 0.062 12.7 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 KEP65252.1 - 0.08 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.7 KEP65252.1 - 0.091 11.8 0.0 0.75 8.8 0.0 2.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.7 KEP65252.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 KEP65252.1 - 0.13 11.7 0.0 8.7 5.8 0.0 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KEP65252.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PBP1_TM PF14812.1 KEP65252.1 - 0.63 10.3 6.3 1.1 9.5 4.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-CCCH PF00642.19 KEP65253.1 - 6.9e-06 25.6 10.3 0.00026 20.6 1.6 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mitofilin PF09731.4 KEP65254.1 - 3e-13 49.3 28.7 8.4e-10 37.9 15.8 3.2 2 1 0 2 2 2 2 Mitochondrial inner membrane protein MmgE_PrpD PF03972.9 KEP65255.1 - 3.4e-50 170.5 0.2 3.9e-43 147.2 0.1 2.0 2 0 0 2 2 2 2 MmgE/PrpD family zf-rbx1 PF12678.2 KEP65256.1 - 7.4e-36 122.0 11.8 9.2e-36 121.8 8.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEP65256.1 - 4.6e-17 61.6 9.3 6e-17 61.2 6.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KEP65256.1 - 2e-07 30.7 11.9 1.2e-06 28.2 8.3 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEP65256.1 - 0.0014 18.2 11.2 0.014 15.0 7.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP65256.1 - 0.002 18.1 3.1 0.002 18.1 2.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP65256.1 - 0.0039 16.8 9.3 0.28 10.8 6.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP65256.1 - 0.26 11.0 10.0 1.1 9.0 6.9 2.0 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 KEP65256.1 - 0.28 11.1 8.0 2.4 8.1 5.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KEP65256.1 - 1.1 9.0 6.9 22 4.8 4.8 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 KEP65256.1 - 1.2 9.1 8.9 2.6 8.0 6.2 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEP65256.1 - 3.5 7.8 10.6 1.2e+02 2.8 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain WD40 PF00400.27 KEP65258.1 - 7e-18 63.7 20.4 4.6e-08 32.6 1.6 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Gelsolin PF00626.17 KEP65259.1 - 0.11 12.1 0.4 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 Gelsolin repeat Cren7 PF11520.3 KEP65260.1 - 0.0075 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Chromatin protein Cren7 LANC_like PF05147.8 KEP65261.1 - 2.7e-62 210.4 0.0 3.2e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Methyltransf_31 PF13847.1 KEP65262.1 - 4e-15 55.7 0.0 2.6e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KEP65262.1 - 2e-14 54.0 0.6 3.6e-10 40.3 0.1 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KEP65262.1 - 6.3e-11 42.6 0.3 3.7e-05 24.1 0.0 3.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_26 PF13659.1 KEP65262.1 - 3.6e-10 39.9 0.6 4e-05 23.6 0.1 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KEP65262.1 - 2.5e-09 37.4 0.1 2.4e-05 24.7 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP65262.1 - 4.8e-09 36.4 0.2 0.00026 21.2 0.0 3.2 3 1 0 3 3 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KEP65262.1 - 6.1e-07 29.2 0.0 0.00017 21.3 0.0 3.2 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 KEP65262.1 - 6e-05 23.8 0.4 0.0028 18.4 0.0 3.5 4 0 0 4 4 4 1 Methyltransferase domain Spermine_synth PF01564.12 KEP65262.1 - 0.00037 19.4 0.0 0.087 11.7 0.0 2.9 3 0 0 3 3 3 1 Spermine/spermidine synthase Methyltransf_32 PF13679.1 KEP65262.1 - 0.0094 15.6 0.0 0.09 12.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.6 KEP65262.1 - 0.076 12.4 0.5 11 5.3 0.0 2.6 3 0 0 3 3 3 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 KEP65262.1 - 0.078 12.3 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Nodulation protein S (NodS) Herpes_UL52 PF03121.10 KEP65264.1 - 1.6e-13 50.1 0.0 1.1e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Herpesviridae UL52/UL70 DNA primase rRNA_proc-arch PF13234.1 KEP65266.1 - 8.6e-72 241.5 0.0 1.4e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KEP65266.1 - 1.5e-51 174.1 5.0 2.3e-51 173.5 1.0 2.7 2 1 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KEP65266.1 - 7.4e-22 77.6 0.1 2.3e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP65266.1 - 4.6e-07 29.6 0.8 1.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP65266.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mob_synth_C PF06463.8 KEP65267.1 - 1.1e-26 92.9 0.0 5.3e-19 68.1 0.0 2.4 2 0 0 2 2 2 2 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KEP65267.1 - 4.4e-18 66.0 0.0 6.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 KEP65267.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 KEP65267.1 - 0.0052 16.8 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain CRAL_TRIO PF00650.15 KEP65268.1 - 4.2e-19 68.5 0.0 6.2e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain ACBP PF00887.14 KEP65268.1 - 3.7e-05 23.2 0.0 7.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein EF-hand_1 PF00036.27 KEP65269.1 - 5e-27 91.1 7.3 2.8e-07 29.3 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP65269.1 - 9e-24 83.3 5.1 4.3e-12 45.9 0.8 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KEP65269.1 - 1.9e-22 77.5 6.1 2e-06 26.8 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KEP65269.1 - 8.9e-20 68.7 6.8 0.001 18.7 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KEP65269.1 - 7.3e-15 54.3 7.6 7.8e-06 25.4 1.6 4.4 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEP65269.1 - 7.6e-09 35.5 0.1 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KEP65269.1 - 1.5e-05 24.6 3.9 0.07 12.8 1.0 3.3 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KEP65269.1 - 0.00045 20.0 0.1 0.03 14.2 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.8 KEP65269.1 - 0.11 12.1 0.1 2.6 7.5 0.0 2.6 1 1 2 3 3 3 0 Caleosin related protein VCBS PF13517.1 KEP65269.1 - 0.64 10.4 4.0 0.81 10.0 0.6 2.5 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Fe-S_biosyn PF01521.15 KEP65270.1 - 3.1e-11 43.1 0.0 1.2e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis UFC1 PF08694.6 KEP65272.1 - 1e-78 262.3 0.1 1.2e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 KEP65272.1 - 0.0024 17.2 0.2 0.016 14.6 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEP65272.1 - 0.097 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RPA_interact_N PF14766.1 KEP65272.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Glyco_hydro_61 PF03443.9 KEP65272.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 Choline_transpo PF04515.7 KEP65273.1 - 3.8e-54 183.6 21.1 8.3e-29 100.3 3.0 2.0 1 1 1 2 2 2 2 Plasma-membrane choline transporter FA_desaturase PF00487.19 KEP65274.1 - 0.0022 17.4 2.2 0.048 13.0 1.2 2.3 2 0 0 2 2 2 1 Fatty acid desaturase DUF3464 PF11947.3 KEP65274.1 - 0.12 11.7 1.2 0.42 10.0 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) MORN PF02493.15 KEP65275.1 - 4.8e-08 32.2 15.5 7.1e-05 22.3 1.3 3.9 4 0 0 4 4 4 3 MORN repeat CIAPIN1 PF05093.8 KEP65276.1 - 0.27 11.3 3.7 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis UCH PF00443.24 KEP65277.1 - 8.6e-44 149.6 0.0 1.2e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP65277.1 - 7.3e-18 65.0 0.0 1e-12 48.1 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KEP65277.1 - 4.2e-13 49.1 0.0 1.5e-12 47.3 0.0 2.0 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KEP65277.1 - 2.5e-08 33.5 0.3 0.00027 20.6 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain BicD PF09730.4 KEP65278.1 - 0.025 12.9 0.2 0.52 8.6 0.0 2.0 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Myb_DNA-binding PF00249.26 KEP65279.1 - 0.022 14.7 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEP65279.1 - 0.056 13.5 0.5 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain RCC1 PF00415.13 KEP65280.1 - 5.3e-40 135.3 5.6 1.9e-07 31.1 0.1 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP65280.1 - 8e-17 60.3 38.7 0.00041 19.8 0.3 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat zf-RanBP PF00641.13 KEP65280.1 - 8.4e-06 24.7 2.3 1.8e-05 23.6 1.6 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Syntaxin-6_N PF09177.6 KEP65282.1 - 6 7.3 16.3 1.6 9.1 4.1 3.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal RNase_PH PF01138.16 KEP65283.1 - 6.6e-16 58.8 0.9 3.4e-15 56.5 0.1 2.5 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEP65283.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 CHCH PF06747.8 KEP65284.1 - 2.2e-06 27.4 5.3 3.4e-06 26.8 3.7 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KEP65284.1 - 0.0018 18.0 2.5 0.022 14.5 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Nol1_Nop2_Fmu PF01189.12 KEP65286.1 - 8.2e-35 120.5 0.0 1.9e-34 119.3 0.0 1.6 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KEP65286.1 - 1.5e-07 31.1 0.0 2.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEP65286.1 - 2e-06 27.1 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEP65286.1 - 0.00026 21.2 0.0 0.00061 20.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KEP65286.1 - 0.00068 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 KEP65286.1 - 0.005 16.2 0.0 0.01 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEP65286.1 - 0.007 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP65286.1 - 0.0081 16.7 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEP65286.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 KEP65286.1 - 0.023 15.5 0.0 0.056 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2458 PF10454.4 KEP65287.1 - 1.1 9.0 7.4 2.7 7.8 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Sulfate_transp PF00916.15 KEP65291.1 - 1.3e-16 60.4 18.4 3.5e-09 36.0 0.4 2.9 3 0 0 3 3 3 2 Sulfate transporter family BiPBP_C PF06832.7 KEP65292.1 - 0.021 14.7 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family HTH_7 PF02796.10 KEP65292.1 - 0.052 13.4 0.1 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Proteasome PF00227.21 KEP65293.1 - 1.7e-62 210.1 0.0 2.8e-62 209.4 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 KEP65293.1 - 9.1e-11 40.8 0.9 1.8e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RecA PF00154.16 KEP65293.1 - 0.093 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein UPF0546 PF10639.4 KEP65294.1 - 9.3e-29 99.5 0.2 3.1e-28 97.8 0.2 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 KEP65294.1 - 0.18 11.8 6.1 0.072 13.1 2.7 1.6 2 0 0 2 2 2 0 EamA-like transporter family DNA_pol_phi PF04931.8 KEP65295.1 - 0.003 15.4 48.2 0.15 9.8 30.6 3.4 2 1 0 2 2 2 2 DNA polymerase phi Tmemb_cc2 PF10267.4 KEP65296.1 - 8 4.9 6.2 14 4.1 4.3 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Kinesin PF00225.18 KEP65297.1 - 3.8e-82 275.6 0.0 5e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Nop14 PF04147.7 KEP65298.1 - 0.14 10.0 4.1 0.18 9.6 2.8 1.0 1 0 0 1 1 1 0 Nop14-like family Dynein_heavy PF03028.10 KEP65299.1 - 2.4e-172 574.6 0.0 6.4e-105 351.7 0.0 3.6 3 1 0 3 3 3 2 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KEP65299.1 - 3.1e-109 365.1 10.5 6.4e-109 364.1 2.9 2.9 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEP65299.1 - 1.1e-73 247.6 0.0 3e-73 246.1 0.0 1.8 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KEP65299.1 - 1e-47 161.8 0.1 3.1e-47 160.3 0.0 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KEP65299.1 - 2.5e-46 157.8 0.1 5.6e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KEP65299.1 - 4.4e-46 157.2 6.0 9.3e-46 156.1 4.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 KEP65299.1 - 2.4e-34 118.6 0.0 8.9e-34 116.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KEP65299.1 - 1.6e-12 47.3 0.0 7.4e-05 22.4 0.0 5.9 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA PF00004.24 KEP65299.1 - 9.3e-06 25.8 0.0 0.11 12.7 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEP65299.1 - 1e-05 26.3 0.0 0.021 15.6 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KEP65299.1 - 1.9e-05 24.7 0.9 0.71 10.0 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.1 KEP65299.1 - 1.9e-05 24.6 0.1 2 8.3 0.0 4.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KEP65299.1 - 5.8e-05 23.4 0.3 0.073 13.3 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.1 KEP65299.1 - 6e-05 22.9 0.1 0.36 10.7 0.0 4.5 4 0 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 KEP65299.1 - 0.0031 17.2 0.1 0.024 14.3 0.0 2.6 3 0 0 3 3 3 1 Archaeal ATPase Baculo_PEP_C PF04513.7 KEP65299.1 - 0.0037 17.0 0.8 0.0037 17.0 0.5 6.7 6 2 1 7 7 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_29 PF13555.1 KEP65299.1 - 0.095 12.2 6.0 4.8 6.7 0.1 3.9 4 0 0 4 4 4 0 P-loop containing region of AAA domain UPF0079 PF02367.12 KEP65299.1 - 0.25 10.9 0.4 21 4.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 KEP65299.1 - 0.28 10.8 0.8 20 4.8 0.1 3.9 4 0 0 4 4 4 0 NTPase RNA_helicase PF00910.17 KEP65299.1 - 0.9 9.7 0.0 54 4.0 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Tubulin_2 PF13809.1 KEP65299.1 - 0.93 8.3 0.1 8.9 5.1 0.0 2.1 2 0 0 2 2 2 0 Tubulin like Sec8_exocyst PF04048.9 KEP65299.1 - 1.8 8.2 20.5 0.025 14.1 0.4 5.7 6 0 0 6 6 6 0 Sec8 exocyst complex component specific domain SWIRM PF04433.12 KEP65300.1 - 1e-21 76.8 0.0 2.5e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KEP65300.1 - 3.2e-10 39.8 0.0 8.7e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEP65300.1 - 1.8e-06 27.9 0.1 6.5e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain FAM176 PF14851.1 KEP65301.1 - 8.9 5.9 11.5 3.3 7.3 2.3 2.8 2 0 0 2 2 2 0 FAM176 family DUF4205 PF13898.1 KEP65302.1 - 2.1e-49 168.1 0.0 3.2e-41 141.2 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4205) EF-hand_7 PF13499.1 KEP65302.1 - 0.0045 17.1 0.0 0.022 14.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Pinin_SDK_memA PF04696.8 KEP65304.1 - 1.3e-11 44.1 13.1 1.3e-11 44.1 9.1 2.2 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Cu_amine_oxid PF01179.15 KEP65305.1 - 1.1e-77 261.4 1.0 1.9e-77 260.7 0.7 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.18 KEP65305.1 - 3.3e-30 104.9 0.0 5.9e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 MAM domain CHASE3 PF05227.8 KEP65308.1 - 0.06 13.0 15.3 0.62 9.7 8.0 2.5 1 1 1 2 2 2 0 CHASE3 domain MA3 PF02847.12 KEP65309.1 - 5.7e-46 154.8 8.4 1.6e-16 59.9 0.0 3.2 3 0 0 3 3 3 3 MA3 domain Mnd1 PF03962.10 KEP65309.1 - 0.028 14.0 0.1 0.055 13.1 0.1 1.5 1 0 0 1 1 1 0 Mnd1 family DUF3921 PF13060.1 KEP65309.1 - 0.092 12.6 0.2 18 5.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3921) EGF_3 PF12947.2 KEP65310.1 - 2.5e-06 27.3 97.5 2.4e-05 24.1 7.1 11.8 11 0 0 11 11 11 6 EGF domain FXa_inhibition PF14670.1 KEP65310.1 - 0.0077 16.3 5.7 0.0077 16.3 3.9 11.7 7 3 4 11 11 11 4 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 KEP65310.1 - 0.016 14.9 4.1 0.016 14.9 2.9 7.7 8 0 0 8 8 8 0 MSP1 EGF domain 1 HemX PF04375.9 KEP65310.1 - 0.022 13.3 0.1 0.032 12.8 0.1 1.1 1 0 0 1 1 1 0 HemX cEGF PF12662.2 KEP65310.1 - 0.025 14.1 0.6 0.025 14.1 0.4 9.8 10 0 0 10 10 10 0 Complement Clr-like EGF-like WND PF07861.6 KEP65310.1 - 1 8.3 6.6 0.83 8.6 2.6 2.1 2 0 0 2 2 2 0 WisP family N-Terminal Region SRP19 PF01922.12 KEP65311.1 - 1.9e-24 86.0 0.2 2.5e-24 85.6 0.1 1.1 1 0 0 1 1 1 1 SRP19 protein HSP20 PF00011.16 KEP65312.1 - 9.1e-27 92.9 0.3 1.4e-26 92.2 0.2 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 KEP65312.1 - 0.08 12.7 0.4 0.15 11.7 0.1 1.6 2 0 0 2 2 2 0 BON domain zf-C2H2_4 PF13894.1 KEP65313.1 - 1.2e-05 25.2 2.1 0.072 13.4 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEP65313.1 - 5.5e-05 23.1 3.1 0.0017 18.4 0.6 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KEP65313.1 - 0.0023 18.1 2.0 0.32 11.4 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type LIM PF00412.17 KEP65313.1 - 0.025 14.6 2.1 0.041 13.9 1.5 1.3 1 0 0 1 1 1 0 LIM domain zf-Di19 PF05605.7 KEP65313.1 - 0.12 12.4 3.8 0.87 9.7 2.7 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KEP65313.1 - 0.21 11.5 0.1 0.21 11.5 0.0 2.2 1 1 1 2 2 2 0 C2H2-type zinc finger PyrI_C PF02748.10 KEP65313.1 - 3 7.3 4.6 1.4 8.4 0.4 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Kin17_mid PF10357.4 KEP65314.1 - 3.5e-42 143.0 3.0 9.5e-42 141.6 2.1 1.8 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 KEP65314.1 - 0.013 15.7 3.2 0.028 14.6 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEP65314.1 - 0.059 13.5 4.1 0.14 12.3 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Kinesin PF00225.18 KEP65317.1 - 1.1e-94 316.8 0.0 1.4e-94 316.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MMR_HSR1 PF01926.18 KEP65319.1 - 1.1e-20 73.6 0.0 1.9e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP65319.1 - 2.1e-08 33.5 0.0 3e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEP65319.1 - 5.1e-08 32.9 0.1 1.3e-05 25.1 0.0 2.3 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 KEP65319.1 - 5.7e-08 32.4 0.0 0.02 14.3 0.0 3.2 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 KEP65319.1 - 4.4e-07 29.2 0.0 8e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KEP65319.1 - 1.5e-05 25.4 0.0 0.00018 21.9 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 KEP65319.1 - 0.00033 20.1 0.0 0.29 10.6 0.0 2.7 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KEP65319.1 - 0.018 14.2 0.0 0.079 12.2 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.17 KEP65319.1 - 0.021 14.2 0.0 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 Ras family ABC_tran PF00005.22 KEP65319.1 - 0.028 14.7 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.5 KEP65319.1 - 0.039 13.1 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KEP65319.1 - 0.051 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_21 PF13304.1 KEP65319.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Redoxin PF08534.5 KEP65320.1 - 4.7e-26 91.0 0.0 6.8e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEP65320.1 - 2.7e-11 43.2 0.0 3.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family S1 PF00575.18 KEP65321.1 - 9e-25 86.5 0.4 5.4e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 S1 RNA binding domain DUF2937 PF11157.3 KEP65321.1 - 0.057 12.7 1.8 1.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Ribosomal_S14 PF00253.16 KEP65322.1 - 1.7e-18 65.7 4.4 4.9e-18 64.2 3.0 1.9 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Abhydrolase_6 PF12697.2 KEP65325.1 - 6.4e-12 45.8 0.1 1.7e-10 41.1 0.0 3.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP65325.1 - 2.8e-06 27.1 0.0 1.3e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEP65325.1 - 7.4e-06 25.7 0.2 0.00049 19.9 0.0 2.7 2 0 0 2 2 2 1 Putative lysophospholipase LSM PF01423.17 KEP65327.1 - 4.5e-17 61.3 0.0 5.4e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain RNase_PH PF01138.16 KEP65328.1 - 7.5e-14 52.1 0.1 3.9e-13 49.8 0.1 2.2 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEP65328.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF1625 PF07787.7 KEP65330.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) DUF1343 PF07075.6 KEP65330.1 - 0.022 13.6 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) PIG-F PF06699.6 KEP65332.1 - 2.8e-06 27.4 2.5 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 GPI biosynthesis protein family Pig-F EmrE PF13536.1 KEP65333.1 - 8.7e-08 32.3 1.2 8.7e-08 32.3 0.9 3.5 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF4231 PF14015.1 KEP65333.1 - 0.067 13.1 0.6 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) FUSC PF04632.7 KEP65333.1 - 0.14 10.5 3.7 0.24 9.7 2.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF202 PF02656.10 KEP65333.1 - 0.33 11.2 6.9 7.8 6.7 0.5 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF202) ABA_GPCR PF12430.3 KEP65334.1 - 7e-45 152.5 11.9 7e-45 152.5 8.2 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KEP65334.1 - 1.4e-19 69.8 0.1 3.5e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) Pkinase PF00069.20 KEP65335.1 - 3.8e-66 222.8 0.0 5.1e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65335.1 - 2.6e-36 125.0 0.0 3.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP65335.1 - 2.2e-05 23.5 0.0 3.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KEP65335.1 - 0.018 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KEP65335.1 - 0.037 13.7 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KEP65335.1 - 0.059 12.4 0.0 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2408 PF10303.4 KEP65337.1 - 0.0034 17.4 2.0 0.0047 17.0 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) MIP-T3 PF10243.4 KEP65337.1 - 0.042 12.3 6.0 0.047 12.1 4.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3373 PF11853.3 KEP65337.1 - 0.15 10.5 2.0 0.19 10.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) OmpH PF03938.9 KEP65337.1 - 1.3 8.9 5.3 1.8 8.5 3.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CCT_2 PF09425.5 KEP65338.1 - 0.0011 18.4 1.3 0.002 17.6 0.9 1.4 1 0 0 1 1 1 1 Divergent CCT motif DUF3357 PF11837.3 KEP65338.1 - 0.016 15.0 0.1 1.6 8.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) P12 PF12669.2 KEP65338.1 - 0.074 13.2 0.4 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family 2HCT PF03390.10 KEP65338.1 - 0.11 10.8 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family DUF780 PF05611.6 KEP65338.1 - 0.24 12.1 2.0 0.36 11.5 1.4 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) TUDOR PF00567.19 KEP65339.1 - 4.9e-08 32.8 1.2 1.1e-06 28.5 0.0 2.7 2 2 0 2 2 2 1 Tudor domain SMN PF06003.7 KEP65339.1 - 0.00025 20.2 1.0 0.00025 20.2 0.7 2.1 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) Tmemb_cc2 PF10267.4 KEP65339.1 - 0.00057 18.5 1.0 0.0011 17.6 0.7 1.4 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Erp_C PF06780.6 KEP65339.1 - 0.024 14.5 2.4 0.067 13.0 1.6 1.8 1 0 0 1 1 1 0 Erp protein C-terminus Fis1_TPR_C PF14853.1 KEP65339.1 - 0.24 11.3 1.7 0.6 10.0 1.2 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF4475 PF14753.1 KEP65341.1 - 3.7e-46 157.1 9.5 5.3e-33 114.1 4.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4475) GTP_EFTU PF00009.22 KEP65342.1 - 2.3e-56 190.1 0.0 3.9e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEP65342.1 - 5.1e-36 122.8 0.4 2.8e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEP65342.1 - 9e-15 54.5 0.4 3e-14 52.8 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEP65342.1 - 0.00017 21.4 0.0 0.00057 19.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KEP65342.1 - 0.00096 18.7 0.2 0.0033 17.0 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 FlpD PF02662.11 KEP65342.1 - 0.021 14.5 0.1 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.13 KEP65342.1 - 0.075 12.8 0.3 0.26 11.1 0.1 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain FAST_1 PF06743.10 KEP65343.1 - 0.00014 21.5 0.4 0.5 10.1 0.0 4.7 5 1 1 6 6 6 2 FAST kinase-like protein, subdomain 1 Ctr PF04145.10 KEP65344.1 - 3.3 7.7 1.6 36 4.3 0.3 3.6 2 0 0 2 2 2 0 Ctr copper transporter family TPR_12 PF13424.1 KEP65346.1 - 2.4e-09 36.9 19.9 0.058 13.3 0.2 5.1 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 KEP65346.1 - 4.7e-07 29.2 14.6 0.0073 16.1 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEP65346.1 - 7.8e-05 22.1 10.9 0.017 14.7 1.4 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEP65346.1 - 0.00019 21.0 12.5 0.2 11.3 0.2 4.6 5 0 0 5 5 5 2 TPR repeat TPR_8 PF13181.1 KEP65346.1 - 0.00029 20.3 3.2 12 5.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP65346.1 - 0.00033 20.2 5.6 0.9 9.4 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat WASH-7_N PF14745.1 KEP65346.1 - 0.04 12.1 0.2 0.055 11.6 0.2 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal SNAP PF14938.1 KEP65346.1 - 0.063 12.4 6.8 0.11 11.5 4.7 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.9 KEP65346.1 - 0.22 12.0 0.0 0.22 12.0 0.0 5.1 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEP65346.1 - 0.38 11.0 1.6 70 4.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP65346.1 - 0.64 10.6 11.3 15 6.2 0.5 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP65346.1 - 0.96 10.2 19.9 3 8.7 0.5 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3366 PF11846.3 KEP65346.1 - 1.3 8.8 6.0 1.2 9.0 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) Kelch_4 PF13418.1 KEP65348.1 - 2.4e-51 171.2 9.4 1.4e-09 37.5 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP65348.1 - 2.2e-47 158.2 19.9 7.4e-09 35.5 0.1 7.4 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KEP65348.1 - 4.9e-45 150.8 0.0 4.7e-08 32.8 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KEP65348.1 - 5.5e-44 146.3 1.1 7e-08 31.9 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KEP65348.1 - 1.7e-41 139.5 0.0 1.3e-06 27.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KEP65348.1 - 3.7e-36 121.8 1.2 1.4e-05 25.0 0.0 6.4 5 1 1 6 6 6 6 Kelch motif BTB PF00651.26 KEP65348.1 - 8.1e-22 77.3 0.3 1.7e-20 73.0 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain RAG2 PF03089.9 KEP65348.1 - 0.017 13.8 0.0 1.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Recombination activating protein 2 BACK PF07707.10 KEP65348.1 - 0.032 14.0 0.4 0.12 12.2 0.0 2.1 3 0 0 3 3 3 0 BTB And C-terminal Kelch Epimerase PF01370.16 KEP65350.1 - 7e-39 133.6 0.0 1.7e-35 122.6 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEP65350.1 - 0.001 18.0 0.1 0.081 11.8 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KEP65350.1 - 0.008 15.0 0.0 0.59 8.9 0.0 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEP65350.1 - 0.077 11.8 0.1 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sporozoite_P67 PF05642.6 KEP65350.1 - 0.6 7.8 8.4 0.77 7.5 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 KEP65350.1 - 0.67 8.1 5.8 0.81 7.8 4.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 KEP65350.1 - 1.5 7.5 4.0 2 7.1 2.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.6 KEP65350.1 - 9.9 4.1 13.1 13 3.6 9.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Metallophos PF00149.23 KEP65351.1 - 1.1e-39 135.8 0.1 1.5e-39 135.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NYD-SP12_N PF15015.1 KEP65351.1 - 0.0054 15.0 0.0 0.0077 14.5 0.0 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal tRNA-synt_1g PF09334.6 KEP65353.1 - 2e-42 145.2 0.0 1.5e-22 79.8 0.0 6.1 6 0 0 6 6 6 5 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEP65353.1 - 2.5e-07 29.1 0.0 0.00049 18.2 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEP65353.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA PAN_4 PF14295.1 KEP65356.1 - 4.8e-30 103.0 30.8 2.5e-09 36.7 0.7 4.7 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.21 KEP65356.1 - 1.3e-25 88.8 16.2 7.2e-08 32.0 0.3 4.3 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.7 KEP65356.1 - 5.2e-08 32.3 19.8 0.03 13.9 0.1 4.3 4 0 0 4 4 4 4 PAN-like domain Sld5 PF05916.6 KEP65357.1 - 1.4e-08 34.9 0.2 2.4e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein Guanylate_cyc_2 PF09778.4 KEP65358.1 - 5.9e-28 97.5 0.1 1.3e-16 60.4 0.0 3.2 3 0 0 3 3 3 3 Guanylylate cyclase Peptidase_C39 PF03412.10 KEP65358.1 - 0.00091 19.0 0.0 0.0076 16.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase C39 family Peptidase_C39_2 PF13529.1 KEP65358.1 - 0.0029 17.9 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase_C39 like family Phytochelatin PF05023.9 KEP65358.1 - 0.11 11.3 0.1 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Phytochelatin synthase Peptidase_S9_N PF02897.10 KEP65359.1 - 4.7e-112 374.6 2.6 7.2e-112 373.9 1.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 KEP65359.1 - 3.7e-65 219.1 0.1 1.1e-64 217.6 0.0 1.8 1 0 0 1 1 1 1 Prolyl oligopeptidase family SUI1 PF01253.17 KEP65361.1 - 4e-29 100.2 0.5 4.9e-29 99.9 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 GTP_EFTU PF00009.22 KEP65362.1 - 1.1e-39 135.8 0.0 1.5e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KEP65362.1 - 3.2e-24 84.7 0.0 1.4e-23 82.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KEP65362.1 - 4.8e-21 74.4 0.0 2.5e-20 72.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 KEP65362.1 - 1.4e-06 28.0 0.0 4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KEP65362.1 - 8.8e-06 25.7 0.2 2.4e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 KEP65362.1 - 1.1e-05 25.9 0.0 3.7e-05 24.2 0.0 2.0 2 0 0 2 2 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEP65362.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEP65362.1 - 0.0047 16.7 0.0 2.3 8.0 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Arf PF00025.16 KEP65362.1 - 0.0067 15.6 0.0 3 7.0 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family SRPRB PF09439.5 KEP65362.1 - 0.014 14.5 0.0 0.46 9.6 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KEP65362.1 - 0.042 13.8 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 KEP65362.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 KEP65362.1 - 0.18 11.1 0.0 0.78 9.1 0.0 2.0 1 1 0 1 1 1 0 Ras family Pet191_N PF10203.4 KEP65363.1 - 1e-19 70.3 4.8 1.1e-19 70.1 3.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KEP65363.1 - 1.2 8.9 5.0 20 5.0 0.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Mtc PF03820.12 KEP65364.1 - 2e-67 227.0 0.0 2.2e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Tic22 PF04278.7 KEP65365.1 - 2.5e-18 66.3 0.1 4.5e-17 62.2 0.0 2.7 2 1 0 2 2 2 1 Tic22-like family Afi1 PF07792.7 KEP65365.1 - 0.41 10.6 1.6 11 6.0 1.0 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MLANA PF14991.1 KEP65370.1 - 5.3e-05 23.2 0.3 0.041 13.9 0.0 2.5 2 0 0 2 2 2 2 Protein melan-A SKG6 PF08693.5 KEP65370.1 - 0.0021 17.3 2.1 0.0048 16.1 1.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 KEP65370.1 - 0.011 14.5 0.4 0.022 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Adeno_E3_CR2 PF02439.10 KEP65370.1 - 0.025 14.1 0.2 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KEP65370.1 - 0.032 13.8 0.1 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4059 PF13268.1 KEP65370.1 - 0.033 14.3 0.1 0.099 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) TMEM223 PF14640.1 KEP65370.1 - 0.04 13.8 0.0 9.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 223 DUF347 PF03988.7 KEP65370.1 - 0.051 13.4 0.8 0.31 10.9 0.0 2.4 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) BatA PF07584.6 KEP65370.1 - 0.051 13.7 0.8 0.68 10.1 0.1 2.4 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Protocadherin PF08374.6 KEP65370.1 - 0.085 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Protocadherin DUF4381 PF14316.1 KEP65370.1 - 0.092 12.8 0.8 0.33 11.0 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Neurensin PF14927.1 KEP65370.1 - 0.096 12.0 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Neurensin FixQ PF05545.6 KEP65370.1 - 0.16 11.6 0.3 0.37 10.4 0.2 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ BatD PF13584.1 KEP65370.1 - 0.19 10.2 0.0 0.33 9.5 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance Lamp PF01299.12 KEP65370.1 - 0.37 9.8 0.0 0.37 9.8 0.0 2.0 3 0 0 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) TBPIP PF07106.8 KEP65371.1 - 0.0001 21.8 6.4 0.00076 19.0 0.1 3.0 3 0 0 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATP-synt_D PF01813.12 KEP65371.1 - 2.1 7.8 18.8 0.032 13.7 1.6 3.2 3 0 0 3 3 3 0 ATP synthase subunit D Filamin PF00630.14 KEP65372.1 - 3.4e-27 94.9 0.1 8.3e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 Filamin/ABP280 repeat PGM_PMM_I PF02878.11 KEP65373.1 - 5.9e-27 93.8 0.0 8.8e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KEP65373.1 - 7.1e-25 87.2 0.0 1.7e-24 86.0 0.0 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KEP65373.1 - 4.5e-11 42.9 0.1 5e-10 39.6 0.0 2.8 2 1 1 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KEP65373.1 - 3.5e-06 26.9 0.0 9.3e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF3419 PF11899.3 KEP65373.1 - 0.041 12.5 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Ribosomal_S5 PF00333.15 KEP65374.1 - 2.8e-07 30.1 0.0 5.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KEP65374.1 - 1.6e-05 24.0 0.0 8.5e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain dsrm PF00035.20 KEP65374.1 - 0.07 13.7 0.0 0.26 11.9 0.0 2.0 1 0 0 1 1 1 0 Double-stranded RNA binding motif Methyltrn_RNA_3 PF02598.12 KEP65375.1 - 1.7e-72 244.2 0.0 2.4e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase Germane PF10646.4 KEP65375.1 - 0.04 14.0 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Sporulation and spore germination HAP2-GCS1 PF10699.4 KEP65376.1 - 2.4e-13 49.8 0.0 9.4e-13 47.9 0.0 2.2 1 0 0 1 1 1 1 Male gamete fusion factor GST_N PF02798.15 KEP65378.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain AP2 PF00847.15 KEP65379.1 - 3e-08 33.6 16.2 3.3e-07 30.3 2.0 2.9 3 0 0 3 3 3 2 AP2 domain SAG PF04092.8 KEP65380.1 - 1.3e-16 61.1 19.8 4.3e-11 43.2 0.6 2.1 2 0 0 2 2 2 2 SRS domain s48_45 PF07422.8 KEP65380.1 - 0.027 14.5 1.3 0.1 12.6 0.0 2.4 2 1 1 3 3 3 0 Sexual stage antigen s48/45 domain Lantibiotic_a PF14867.1 KEP65380.1 - 0.032 13.4 0.6 0.11 11.7 0.0 2.3 2 0 0 2 2 2 0 Lantibiotic alpha FKBP_C PF00254.23 KEP65381.1 - 1.2e-21 76.4 0.0 2.3e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RAP PF08373.5 KEP65382.1 - 1.4e-23 82.4 0.3 2.4e-23 81.6 0.2 1.4 1 0 0 1 1 1 1 RAP domain MMtag PF10159.4 KEP65382.1 - 0.15 12.0 3.9 0.11 12.5 0.8 2.1 2 0 0 2 2 2 0 Kinase phosphorylation protein PPR_3 PF13812.1 KEP65383.1 - 0.00077 19.5 0.1 1.6e+02 2.9 0.0 7.1 6 0 0 6 6 6 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 KEP65383.1 - 0.00087 19.2 0.0 3 7.8 0.0 4.7 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.15 KEP65383.1 - 0.0066 16.3 0.1 18 5.6 0.0 5.1 5 0 0 5 5 5 1 PPR repeat zf-MYND PF01753.13 KEP65385.1 - 3.8e-08 33.0 6.4 9.9e-08 31.7 4.4 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KEP65385.1 - 0.16 11.6 3.6 0.32 10.6 2.5 1.5 1 0 0 1 1 1 0 HIT zinc finger SNF PF00209.13 KEP65386.1 - 9.2e-12 44.2 23.2 2.2e-07 29.7 4.9 2.7 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family Spc97_Spc98 PF04130.8 KEP65388.1 - 8.8e-15 54.0 0.0 2.8e-10 39.1 0.0 2.9 2 1 0 2 2 2 2 Spc97 / Spc98 family CLAMP PF14769.1 KEP65389.1 - 1.1e-28 99.3 0.3 1.6e-28 98.7 0.2 1.3 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Pro_isomerase PF00160.16 KEP65390.1 - 4.6e-43 147.0 0.1 5.4e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short PF00106.20 KEP65391.1 - 4.9e-07 29.8 2.8 0.00071 19.5 0.4 2.5 1 1 1 2 2 2 2 short chain dehydrogenase Epimerase PF01370.16 KEP65391.1 - 0.0096 15.3 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RabGAP-TBC PF00566.13 KEP65392.1 - 1.7e-48 164.9 0.0 2.6e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1376 PF07120.6 KEP65392.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) ATP_bind_1 PF03029.12 KEP65393.1 - 1.2e-71 241.0 0.0 1.5e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 KEP65393.1 - 9e-08 31.7 0.0 1.9e-07 30.6 0.0 1.6 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 KEP65393.1 - 1e-05 25.4 0.4 3.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KEP65393.1 - 2.9e-05 23.0 1.2 0.00046 19.0 0.3 2.6 2 1 0 2 2 2 1 ArgK protein SRP54 PF00448.17 KEP65393.1 - 7.5e-05 22.2 1.0 0.01 15.3 0.1 2.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KEP65393.1 - 0.00051 20.8 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KEP65393.1 - 0.002 17.8 0.0 0.0054 16.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.22 KEP65393.1 - 0.0021 17.4 0.0 0.033 13.6 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_30 PF13604.1 KEP65393.1 - 0.0024 17.5 0.1 0.0024 17.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEP65393.1 - 0.0026 18.0 0.0 0.006 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 KEP65393.1 - 0.0027 17.2 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KEP65393.1 - 0.0037 16.8 0.0 0.008 15.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 FeoB_N PF02421.13 KEP65393.1 - 0.0038 16.5 0.0 0.1 11.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B NTPase_1 PF03266.10 KEP65393.1 - 0.0041 16.8 0.0 0.016 14.9 0.0 2.0 2 1 0 2 2 2 1 NTPase MMR_HSR1 PF01926.18 KEP65393.1 - 0.0056 16.6 0.0 0.019 14.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KEP65393.1 - 0.006 16.8 0.1 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.17 KEP65393.1 - 0.0077 15.1 0.1 0.013 14.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.1 KEP65393.1 - 0.0078 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP65393.1 - 0.011 15.7 0.2 0.032 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.12 KEP65393.1 - 0.012 14.9 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_19 PF13245.1 KEP65393.1 - 0.013 15.2 0.3 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 KEP65393.1 - 0.014 15.0 0.2 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KEP65393.1 - 0.022 14.5 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_31 PF13614.1 KEP65393.1 - 0.027 14.4 0.2 0.51 10.2 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_22 PF13401.1 KEP65393.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KEP65393.1 - 0.033 13.3 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 KEP65393.1 - 0.045 13.1 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEP65393.1 - 0.047 12.7 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 KEP65393.1 - 0.056 12.8 0.0 0.16 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain PEPCK_ATP PF01293.15 KEP65393.1 - 0.062 11.8 0.0 0.096 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_23 PF13476.1 KEP65393.1 - 0.078 13.2 0.1 2.1 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEP65393.1 - 0.081 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 KEP65393.1 - 0.092 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.12 KEP65393.1 - 0.13 12.0 0.2 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 G-alpha PF00503.15 KEP65393.1 - 0.48 9.0 3.7 0.15 10.7 0.5 1.5 2 0 0 2 2 2 0 G-protein alpha subunit 4HBT PF03061.17 KEP65394.1 - 0.00043 20.3 0.0 0.0016 18.5 0.0 1.9 2 0 0 2 2 2 1 Thioesterase superfamily Collagen PF01391.13 KEP65394.1 - 0.0065 15.9 4.9 0.0065 15.9 3.4 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) UFD1 PF03152.9 KEP65395.1 - 1.4e-19 69.8 0.0 4.7e-16 58.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 CytochromB561_N PF09786.4 KEP65395.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal CDC45 PF02724.9 KEP65395.1 - 6.3 4.7 6.0 9.6 4.1 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Notch PF00066.12 KEP65396.1 - 3.8e-50 167.8 115.1 1.4e-09 38.0 8.7 6.2 4 1 2 6 6 6 6 LNR domain Biotin_lipoyl PF00364.17 KEP65397.1 - 3.4e-18 65.0 0.3 5.7e-18 64.3 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KEP65397.1 - 0.00076 19.0 0.3 0.0022 17.5 0.1 1.8 1 1 0 1 1 1 1 Biotin-lipoyl like HlyD PF00529.15 KEP65397.1 - 0.0018 17.6 2.1 0.0037 16.6 1.4 1.5 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 KEP65397.1 - 0.16 11.0 0.5 0.33 10.0 0.3 1.4 1 1 0 1 1 1 0 HlyD family secretion protein Peptidase_M50B PF13398.1 KEP65398.1 - 1.2e-54 184.8 24.5 1.4e-54 184.5 17.0 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M3 PF01432.15 KEP65398.1 - 0.3 10.0 0.6 0.42 9.5 0.4 1.1 1 0 0 1 1 1 0 Peptidase family M3 DSHCT PF08148.7 KEP65399.1 - 2.1e-49 167.2 0.3 8.2e-49 165.2 0.0 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KEP65399.1 - 2.7e-17 62.8 0.0 5e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP65399.1 - 7.6e-06 25.7 0.1 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP65399.1 - 0.001 18.9 0.0 0.031 14.1 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit EMP24_GP25L PF01105.19 KEP65400.1 - 0.0049 16.6 0.7 0.079 12.6 0.0 2.4 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.7 KEP65400.1 - 8.5 6.1 3.8 40 4.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PAP_assoc PF03828.14 KEP65401.1 - 4.3e-08 32.9 0.1 1.1e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEP65401.1 - 0.00026 21.2 0.0 0.00081 19.6 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Ribosomal_L35p PF01632.14 KEP65402.1 - 7.9e-16 57.7 6.0 1.6e-15 56.7 4.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L35 Methyltransf_15 PF09445.5 KEP65403.1 - 8.9e-28 96.8 0.0 1.4e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KEP65403.1 - 1.7e-06 28.0 0.1 7.9e-06 25.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Nucleo_P87 PF07267.6 KEP65403.1 - 1.7 7.1 4.4 5.2 5.6 3.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CHCH PF06747.8 KEP65404.1 - 0.0033 17.2 11.3 0.033 14.1 2.3 2.6 2 1 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 KEP65404.1 - 0.0058 16.3 2.8 0.0058 16.3 1.9 2.4 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 KEP65404.1 - 0.12 12.1 0.6 0.12 12.1 0.4 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 KEP65404.1 - 0.2 11.7 0.4 0.2 11.7 0.3 2.2 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.4 KEP65404.1 - 0.36 10.8 8.1 3 7.9 2.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KEP65404.1 - 0.74 9.8 8.0 1.7 8.7 5.6 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF4131 PF13567.1 KEP65406.1 - 0.0077 15.6 0.6 0.0077 15.6 0.4 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) PRT_C PF08372.5 KEP65406.1 - 0.19 11.2 0.0 0.51 9.8 0.0 1.7 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal DUF2206 PF09971.4 KEP65406.1 - 2 7.1 0.1 3 6.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) HHH PF00633.18 KEP65407.1 - 1.5e-07 30.7 0.0 3.9e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 KEP65407.1 - 3.5e-05 24.0 0.0 0.00019 21.6 0.0 2.2 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NOA36 PF06524.7 KEP65408.1 - 4.4 6.4 9.7 0.25 10.5 2.9 1.7 2 0 0 2 2 2 0 NOA36 protein Patched PF02460.13 KEP65410.1 - 3.3e-97 326.3 15.6 3e-51 174.3 0.0 3.1 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 KEP65410.1 - 2.1e-31 108.4 7.6 2.1e-31 108.4 5.3 2.5 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Cullin PF00888.17 KEP65411.1 - 5.8e-20 71.3 0.0 8e-13 47.7 0.0 4.2 4 0 0 4 4 4 3 Cullin family Cullin_Nedd8 PF10557.4 KEP65411.1 - 1.3e-12 47.3 0.1 2.8e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 Cullin protein neddylation domain HTH_9 PF08221.6 KEP65411.1 - 0.13 12.1 0.4 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Kinesin PF00225.18 KEP65414.1 - 1.2e-98 329.9 0.6 3.8e-98 328.2 0.0 2.1 3 0 0 3 3 3 1 Kinesin motor domain Filament PF00038.16 KEP65414.1 - 0.0038 16.7 8.9 0.0038 16.7 6.1 4.3 2 1 1 4 4 4 2 Intermediate filament protein LMSTEN PF07988.7 KEP65414.1 - 0.048 12.9 6.2 0.056 12.7 0.7 2.8 2 0 0 2 2 2 0 LMSTEN motif Shugoshin_N PF07558.6 KEP65414.1 - 0.39 10.4 13.5 2 8.1 1.1 4.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region CENP-Q PF13094.1 KEP65414.1 - 2 8.4 57.2 0.016 15.2 16.8 4.8 3 2 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF948 PF06103.6 KEP65414.1 - 3.1 7.7 15.4 4.4 7.2 0.2 4.7 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) LRR_4 PF12799.2 KEP65415.1 - 2.9e-15 55.4 0.6 3.5e-09 36.0 0.0 2.3 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEP65415.1 - 2.5e-08 32.8 0.6 0.33 11.1 0.0 3.4 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_8 PF13855.1 KEP65415.1 - 3.3e-07 29.9 0.1 0.0007 19.2 0.0 2.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KEP65415.1 - 1.7e-06 27.2 0.4 1.5 9.3 0.0 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 KEP65415.1 - 6.4e-06 25.7 0.2 1.1 9.5 0.0 3.3 3 0 0 3 3 3 3 Leucine Rich repeat LRR_9 PF14580.1 KEP65415.1 - 0.0028 17.2 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat HTH_Tnp_1 PF01527.15 KEP65416.1 - 1.8e-05 24.6 0.7 0.00031 20.6 0.0 2.8 3 0 0 3 3 3 1 Transposase HTH_23 PF13384.1 KEP65416.1 - 0.00083 18.9 0.5 0.0022 17.5 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MerR PF00376.18 KEP65416.1 - 0.031 13.8 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein MerR_1 PF13411.1 KEP65416.1 - 0.034 13.8 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_17 PF12728.2 KEP65416.1 - 0.041 14.1 2.2 1.5 9.0 0.0 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain AstE_AspA PF04952.9 KEP65416.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family HTH_Tnp_Tc5 PF03221.11 KEP65416.1 - 0.12 12.2 0.2 0.23 11.2 0.2 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Basic PF01586.11 KEP65417.1 - 0.027 15.1 0.5 0.62 10.8 0.2 2.4 2 0 0 2 2 2 0 Myogenic Basic domain Fasciclin PF02469.17 KEP65418.1 - 6.2e-09 35.9 0.0 0.0016 18.4 0.0 3.3 3 0 0 3 3 3 3 Fasciclin domain DnaJ PF00226.26 KEP65419.1 - 5.5e-20 70.8 0.3 1.7e-19 69.2 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain DUF4460 PF14687.1 KEP65419.1 - 0.06 13.0 2.7 0.099 12.4 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) DUF763 PF05559.6 KEP65419.1 - 0.95 8.3 5.9 1.6 7.6 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF2422 PF10337.4 KEP65419.1 - 2 7.1 7.3 2.7 6.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF2229 PF09989.4 KEP65419.1 - 3.7 6.9 9.4 4.1 6.8 5.3 1.8 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1021 PF06257.6 KEP65420.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) DUF1059 PF06348.6 KEP65420.1 - 0.073 12.8 0.2 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) DUF938 PF06080.7 KEP65420.1 - 0.13 11.7 0.0 0.53 9.7 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF938) Steroid_dh PF02544.11 KEP65422.1 - 1.3e-34 119.1 2.6 2.5e-34 118.2 1.8 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 KEP65422.1 - 9.7e-05 21.6 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 KEP65422.1 - 0.0012 19.3 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PRP38 PF03371.10 KEP65423.1 - 1.6e-45 154.8 0.9 2.5e-45 154.2 0.6 1.3 1 0 0 1 1 1 1 PRP38 family CAP_GLY PF01302.20 KEP65424.1 - 2.6e-15 55.8 0.0 7e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KEP65424.1 - 9.2e-09 34.7 3.3 0.68 9.6 2.5 4.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.1 KEP65424.1 - 2.6e-08 33.9 0.0 5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_1 PF00560.28 KEP65424.1 - 0.0019 17.9 5.4 8 6.9 0.0 5.2 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 KEP65424.1 - 0.022 14.8 5.9 34 5.2 0.0 5.6 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KEP65424.1 - 0.39 10.9 4.0 30 5.1 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeat Exonuc_VII_L PF02601.10 KEP65425.1 - 9.8 5.2 12.5 20 4.2 8.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Beta-Casp PF10996.3 KEP65426.1 - 9.5e-28 96.6 0.0 1.9e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain CPSF73-100_C PF11718.3 KEP65426.1 - 1.4e-18 67.0 0.0 4e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.22 KEP65426.1 - 1.2e-11 44.6 0.4 5.6e-11 42.4 0.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KEP65426.1 - 7.1e-11 41.7 0.0 1.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 KEP65426.1 - 2.6e-09 36.9 0.1 7e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEP65426.1 - 0.0017 18.0 0.0 0.0055 16.4 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain zf-RING_2 PF13639.1 KEP65427.1 - 4.6e-14 51.9 7.7 9.7e-14 50.9 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP65427.1 - 5.7e-10 39.1 3.8 5.7e-10 39.1 2.6 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP65427.1 - 1.4e-06 27.8 6.5 2.7e-06 26.9 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP65427.1 - 6.9e-06 25.9 6.2 2e-05 24.5 4.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEP65427.1 - 6e-05 22.7 1.2 0.00015 21.5 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KEP65427.1 - 0.00019 21.0 5.8 0.00047 19.8 4.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 KEP65427.1 - 0.0006 19.7 3.0 0.0014 18.5 2.1 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 KEP65427.1 - 0.0025 17.4 3.8 0.0025 17.4 2.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.7 KEP65427.1 - 0.013 14.8 1.7 0.013 14.8 1.2 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Nse PF11789.3 KEP65427.1 - 0.042 13.3 2.5 0.099 12.1 1.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 KEP65427.1 - 0.16 11.4 0.0 0.57 9.6 0.0 1.9 1 0 0 1 1 1 0 Rad50 zinc hook motif Rtf2 PF04641.7 KEP65427.1 - 0.19 10.8 0.9 14 4.7 0.1 2.4 1 1 1 2 2 2 0 Rtf2 RING-finger Baculo_RING PF05883.6 KEP65427.1 - 0.28 11.0 0.6 0.54 10.0 0.4 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.2 KEP65427.1 - 1.2 9.2 7.5 2.3 8.3 5.2 1.4 1 0 0 1 1 1 0 RING-variant domain S1-P1_nuclease PF02265.11 KEP65428.1 - 9e-30 104.1 0.0 8e-18 64.9 0.0 2.9 2 1 0 2 2 2 2 S1/P1 Nuclease DAZAP2 PF11029.3 KEP65428.1 - 0.12 12.8 0.1 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) Methyltransf_26 PF13659.1 KEP65429.1 - 1.7e-09 37.6 0.1 8.6e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KEP65429.1 - 4.5e-06 26.1 0.0 9.3e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.11 KEP65429.1 - 7.6e-06 25.6 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltrans_SAM PF10672.4 KEP65429.1 - 1.6e-05 23.8 0.0 2.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_18 PF12847.2 KEP65429.1 - 0.00078 20.0 0.0 0.0019 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEP65429.1 - 0.018 14.4 0.0 0.045 13.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_3 PF01596.12 KEP65429.1 - 0.031 13.3 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Pkinase PF00069.20 KEP65431.1 - 3.2e-74 249.3 0.0 3.9e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65431.1 - 2.1e-30 105.6 0.0 2.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP65431.1 - 0.035 13.8 0.3 1.4 8.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEP65431.1 - 0.055 12.5 0.8 0.32 10.0 0.5 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IQ PF00612.22 KEP65432.1 - 0.00034 19.9 0.3 0.0011 18.4 0.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Corona_nucleoca PF00937.13 KEP65432.1 - 1.1 8.1 25.3 0.33 9.8 7.8 2.9 1 1 2 3 3 3 0 Coronavirus nucleocapsid protein DUF2188 PF09954.4 KEP65433.1 - 6.9 6.6 7.3 0.93 9.4 0.7 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Ribosomal_S8e PF01201.17 KEP65436.1 - 3.5e-51 172.7 0.2 4.2e-51 172.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e WD40 PF00400.27 KEP65437.1 - 4.7e-23 80.1 10.9 1.9e-06 27.4 0.3 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEP65437.1 - 0.0034 16.1 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 2 Nup133 N terminal like EPTP PF03736.12 KEP65437.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 EPTP domain EGF PF00008.22 KEP65439.1 - 6.2e-07 29.2 55.3 0.0032 17.3 1.2 6.0 5 1 0 5 5 5 4 EGF-like domain EGF_3 PF12947.2 KEP65439.1 - 3.1e-05 23.8 8.5 3.1e-05 23.8 5.9 5.6 5 1 1 6 6 6 3 EGF domain cEGF PF12662.2 KEP65439.1 - 0.0012 18.4 44.5 0.027 14.1 0.5 6.4 7 0 0 7 7 7 4 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP65439.1 - 0.0013 18.7 57.6 0.023 14.7 4.1 6.0 2 1 3 5 5 5 4 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 KEP65439.1 - 0.0072 16.0 1.2 0.0072 16.0 0.8 5.0 4 1 0 4 4 4 3 MSP1 EGF domain 1 cEGF PF12662.2 KEP65440.1 - 0.00068 19.2 25.6 0.17 11.5 1.3 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP65440.1 - 0.00078 19.5 53.0 0.13 12.4 4.6 4.7 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 KEP65440.1 - 0.0011 18.8 36.6 0.54 10.2 3.8 5.0 4 1 0 4 4 4 4 EGF domain EGF PF00008.22 KEP65440.1 - 0.17 11.8 58.6 0.073 13.0 6.5 5.8 6 0 0 6 6 6 0 EGF-like domain cEGF PF12662.2 KEP65441.1 - 2.7e-09 36.4 88.0 0.0035 16.9 0.7 11.0 11 0 0 11 11 11 7 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP65441.1 - 2.3e-05 24.4 120.0 0.045 13.8 2.1 11.1 7 4 3 10 10 10 6 Coagulation Factor Xa inhibitory site EGF PF00008.22 KEP65441.1 - 4.6e-05 23.2 126.8 0.0014 18.5 4.8 12.3 12 1 0 12 12 12 9 EGF-like domain EGF_3 PF12947.2 KEP65441.1 - 0.0017 18.2 115.0 0.019 14.9 9.3 11.5 10 1 0 10 10 10 6 EGF domain Podoplanin PF05808.6 KEP65441.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Podoplanin hEGF PF12661.2 KEP65441.1 - 6.8 7.0 63.5 3.7 7.8 0.4 11.1 11 0 0 11 11 11 0 Human growth factor-like EGF Peptidase_S9 PF00326.16 KEP65442.1 - 4.9e-32 110.8 0.1 1.3e-24 86.6 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family DPPIV_N PF00930.16 KEP65442.1 - 3.6e-24 85.0 0.0 9e-13 47.5 0.0 4.1 4 0 0 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region E1-E2_ATPase PF00122.15 KEP65443.1 - 5e-12 45.3 6.2 1.7e-06 27.2 0.0 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.21 KEP65443.1 - 4.6e-11 43.5 0.6 5.1e-05 23.7 0.1 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP65443.1 - 3.9e-10 40.2 0.3 0.0022 18.2 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP65443.1 - 2.3e-05 24.2 0.0 0.00026 20.8 0.0 2.7 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEP65443.1 - 0.16 11.5 0.6 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Rpp20 PF12328.3 KEP65444.1 - 0.00028 20.5 0.0 0.0073 15.9 0.0 2.7 3 0 0 3 3 3 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KEP65444.1 - 0.0097 15.4 0.0 0.052 13.1 0.0 2.1 2 1 0 2 2 2 1 Alba Ctr PF04145.10 KEP65446.1 - 0.045 13.8 1.4 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Shisa PF13908.1 KEP65446.1 - 1.9 8.6 3.8 4.9 7.2 2.6 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator ORC2 PF04084.9 KEP65448.1 - 5.2e-38 130.6 0.0 1.1e-37 129.6 0.0 1.5 1 1 0 1 1 1 1 Origin recognition complex subunit 2 Nop16 PF09420.5 KEP65448.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Pkinase PF00069.20 KEP65449.1 - 0.00089 18.4 0.0 0.003 16.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Rhomboid PF01694.17 KEP65450.1 - 3.9e-13 49.6 8.0 3.9e-13 49.6 5.6 2.2 2 1 0 2 2 2 1 Rhomboid family Atracotoxin PF05353.6 KEP65450.1 - 0.046 13.5 0.7 0.093 12.5 0.5 1.5 1 0 0 1 1 1 0 Delta Atracotoxin Ribosomal_S27 PF01599.14 KEP65453.1 - 1.7e-25 88.5 3.1 3.1e-25 87.7 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 KEP65453.1 - 1.2e-15 56.6 0.1 3.5e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KEP65453.1 - 1.3e-09 37.6 0.2 3e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEP65453.1 - 0.0021 18.2 0.0 0.012 15.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain IBR PF01485.16 KEP65453.1 - 0.011 15.6 1.0 0.018 14.9 0.7 1.4 1 0 0 1 1 1 0 IBR domain Cucumo_2B PF03263.8 KEP65453.1 - 0.035 14.3 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 Cucumovirus protein 2B Telomere_Sde2 PF13019.1 KEP65453.1 - 0.046 13.3 0.0 0.046 13.3 0.0 1.8 1 1 1 2 2 2 0 Telomere stability and silencing BIR PF00653.16 KEP65453.1 - 0.82 10.1 3.7 53 4.3 2.6 2.2 1 1 0 1 1 1 0 Inhibitor of Apoptosis domain ASFV_L11L PF05293.6 KEP65454.1 - 0.1 12.7 4.9 0.26 11.4 3.5 1.6 1 1 0 1 1 1 0 African swine fever virus (ASFV) L11L protein zf-RING_2 PF13639.1 KEP65457.1 - 3.7e-05 23.4 2.5 0.00012 21.7 1.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-CCHC_2 PF13696.1 KEP65457.1 - 0.00016 21.1 1.5 0.00033 20.0 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 KEP65457.1 - 0.00046 20.1 5.9 0.0021 18.0 4.1 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP65457.1 - 0.0095 15.5 2.3 0.02 14.5 0.1 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KEP65457.1 - 0.024 14.1 0.1 0.055 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TerY-C PF15616.1 KEP65457.1 - 0.057 13.3 2.7 2.8 7.8 0.2 2.9 2 0 0 2 2 2 0 TerY-C metal binding domain zf-C3HC4 PF00097.20 KEP65457.1 - 2.4 7.8 9.1 0.33 10.6 2.4 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEP65457.1 - 4.7 7.1 13.9 0.029 14.2 3.2 2.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING E1_dh PF00676.15 KEP65458.1 - 6.3e-92 307.4 0.2 7.8e-92 307.1 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KEP65458.1 - 5.1e-09 35.8 1.5 1.9e-08 33.9 1.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KEP65458.1 - 1.8e-06 27.0 0.0 2.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 KEP65458.1 - 0.00013 20.9 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Ribosomal_L21e PF01157.13 KEP65459.1 - 1.9e-36 123.8 3.9 2.5e-36 123.4 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e ARGLU PF15346.1 KEP65459.1 - 0.018 14.8 1.8 0.026 14.2 1.3 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF1103 PF06513.6 KEP65459.1 - 0.13 11.6 1.0 0.18 11.1 0.7 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) MORN PF02493.15 KEP65460.1 - 6.2e-58 189.2 87.0 3.6e-09 35.8 1.3 11.1 11 0 0 11 11 11 9 MORN repeat SNF2_N PF00176.18 KEP65461.1 - 2.6e-30 105.2 0.0 1.6e-18 66.5 0.0 2.7 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP65461.1 - 7.6e-10 38.5 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PIP5K PF01504.13 KEP65462.1 - 1.2e-50 171.9 0.0 4.5e-20 71.8 0.0 3.2 3 0 0 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.27 KEP65464.1 - 1.1e-08 34.5 16.9 0.0038 17.0 0.2 7.0 8 0 0 8 8 8 3 WD domain, G-beta repeat CENP-Q PF13094.1 KEP65465.1 - 0.00034 20.6 0.7 0.00079 19.4 0.5 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Viral_P18 PF04521.8 KEP65465.1 - 0.039 13.3 0.4 0.039 13.3 0.3 1.8 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein YlqD PF11068.3 KEP65465.1 - 0.06 13.3 1.1 11 6.1 0.3 2.6 3 0 0 3 3 3 0 YlqD protein bZIP_2 PF07716.10 KEP65465.1 - 0.85 9.4 10.3 0.14 11.9 3.9 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Img2 PF05046.9 KEP65467.1 - 8.2e-18 64.4 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SspB PF04386.8 KEP65467.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Stringent starvation protein B Abhydrolase_5 PF12695.2 KEP65468.1 - 1.5e-16 60.4 3.1 2.7e-14 53.1 2.2 3.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP65468.1 - 1.1e-07 31.9 0.3 9.1e-06 25.7 0.2 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEP65468.1 - 1.6e-06 27.4 0.0 0.0006 19.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.9 KEP65468.1 - 0.024 13.8 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase SprT-like PF10263.4 KEP65469.1 - 4.7e-41 140.0 1.8 7.9e-41 139.3 1.2 1.4 1 0 0 1 1 1 1 SprT-like family WLM PF08325.5 KEP65469.1 - 0.28 11.0 4.2 0.88 9.4 2.8 1.9 1 1 0 1 1 1 0 WLM domain MIF4G PF02854.14 KEP65471.1 - 7.1e-39 133.3 1.6 2.2e-19 69.7 0.1 4.4 4 0 0 4 4 4 4 MIF4G domain Upf2 PF04050.9 KEP65471.1 - 0.016 15.0 0.4 0.016 15.0 0.3 3.9 3 1 0 3 3 3 0 Up-frameshift suppressor 2 DUF4145 PF13643.1 KEP65472.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) RNA_pol PF00940.14 KEP65473.1 - 2.1e-128 428.2 0.0 2.8e-105 352.1 0.0 2.3 2 0 0 2 2 2 2 DNA-dependent RNA polymerase RPOL_N PF14700.1 KEP65473.1 - 6.9e-17 61.6 8.1 4.2e-08 32.8 0.0 4.5 4 0 0 4 4 4 3 DNA-directed RNA polymerase N-terminal SAG PF04092.8 KEP65474.1 - 7.5e-11 42.4 0.1 6.2e-07 29.8 0.3 2.3 2 0 0 2 2 2 2 SRS domain DUF1731 PF08338.6 KEP65475.1 - 4.6e-16 58.0 0.3 9.4e-16 57.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.16 KEP65475.1 - 1.5e-06 27.8 0.1 0.012 15.0 0.0 4.0 4 0 0 4 4 4 3 NAD dependent epimerase/dehydratase family DUF3886 PF13025.1 KEP65476.1 - 0.011 15.6 4.5 0.011 15.6 3.1 8.0 8 2 0 8 8 8 0 Protein of unknown function (DUF3886) Phosducin PF02114.11 KEP65477.1 - 3.1e-12 45.7 0.0 1.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Phosducin DUF1045 PF06299.7 KEP65477.1 - 0.021 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) DUF2129 PF09902.4 KEP65477.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) SPX PF03105.14 KEP65477.1 - 0.4 10.4 4.2 0.69 9.6 2.9 1.5 1 1 0 1 1 1 0 SPX domain HAD PF12710.2 KEP65478.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_3 PF13640.1 KEP65479.1 - 4.7e-11 43.0 0.1 2.2e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEP65479.1 - 4.7e-05 22.9 0.1 0.0001 21.8 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_14 PF13428.1 KEP65479.1 - 0.0017 18.8 0.5 0.011 16.3 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEP65479.1 - 0.002 17.8 0.1 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEP65479.1 - 0.011 15.3 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 TPR repeat TPR_4 PF07721.9 KEP65479.1 - 0.066 13.6 1.3 0.19 12.2 0.9 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.15 KEP65479.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_8 PF13181.1 KEP65479.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Serpin PF00079.15 KEP65480.1 - 1.9e-74 251.0 0.8 2.4e-74 250.7 0.5 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) 2OG-FeII_Oxy PF03171.15 KEP65481.1 - 0.0023 18.1 0.3 0.41 10.9 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Phage_holin_6 PF10746.4 KEP65483.1 - 0.14 11.8 0.5 0.36 10.5 0.3 1.6 1 0 0 1 1 1 0 Phage holin family 6 ARID PF01388.16 KEP65485.1 - 1.2e-11 44.3 0.1 2.3e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TauE PF01925.14 KEP65486.1 - 4.8e-12 45.8 11.8 7.5e-12 45.2 8.2 1.3 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE MFS_1 PF07690.11 KEP65486.1 - 0.00025 19.8 10.6 0.00043 19.1 7.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GPI2 PF06432.6 KEP65486.1 - 0.069 12.4 1.2 2.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4131 PF13567.1 KEP65486.1 - 2.4 7.5 9.0 0.48 9.8 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Miff PF05644.6 KEP65488.1 - 0.034 13.7 0.1 0.077 12.6 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF904 PF06005.7 KEP65488.1 - 7.1 7.0 7.4 0.52 10.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) zf-CCCH PF00642.19 KEP65489.1 - 5.4e-05 22.7 12.4 0.00079 19.0 2.5 3.1 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-LITAF-like PF10601.4 KEP65490.1 - 2e-15 56.3 6.5 2e-15 56.3 4.5 2.5 3 0 0 3 3 3 1 LITAF-like zinc ribbon domain DiS_P_DiS PF06750.8 KEP65490.1 - 0.048 13.4 4.2 0.13 12.1 0.5 2.3 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Zn-ribbon_8 PF09723.5 KEP65490.1 - 0.12 12.3 1.5 4 7.4 0.0 2.9 3 0 0 3 3 3 0 Zinc ribbon domain YABBY PF04690.8 KEP65490.1 - 3.7 7.7 7.9 0.19 11.9 0.8 2.2 2 0 0 2 2 2 0 YABBY protein Cys_rich_CPXG PF14255.1 KEP65490.1 - 8.5 6.2 5.8 1.8 8.4 0.3 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG CRAL_TRIO PF00650.15 KEP65491.1 - 1.8e-33 115.2 0.0 3.1e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KEP65491.1 - 6.5e-15 55.3 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEP65491.1 - 2.5e-07 30.7 0.0 7.5e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DnaJ-X PF14308.1 KEP65492.1 - 5.4e-55 185.8 14.8 1.6e-52 177.8 10.3 2.7 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 KEP65492.1 - 5e-24 83.8 2.8 1.3e-23 82.4 1.9 1.8 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.6 KEP65492.1 - 3.2e-07 30.4 1.0 8.8e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain Pex24p PF06398.6 KEP65493.1 - 0.0026 16.6 0.4 0.0034 16.2 0.3 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Tetraspannin PF00335.15 KEP65493.1 - 2.5 7.3 10.6 0.74 9.0 5.2 1.7 1 1 0 1 1 1 0 Tetraspanin family HTH_22 PF13309.1 KEP65494.1 - 0.022 14.4 0.1 0.05 13.3 0.1 1.6 1 0 0 1 1 1 0 HTH domain PAP2_C PF14360.1 KEP65497.1 - 2.3e-12 46.9 5.0 6.6e-08 32.7 0.5 2.3 2 0 0 2 2 2 2 PAP2 superfamily C-terminal PRP21_like_P PF12230.3 KEP65498.1 - 1.4e-44 152.3 25.2 3.1e-43 147.9 12.3 2.8 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KEP65498.1 - 3e-38 129.2 4.4 1.4e-19 69.4 0.8 2.5 2 0 0 2 2 2 2 Surp module DUF1682 PF07946.9 KEP65498.1 - 0.003 16.4 0.4 0.003 16.4 0.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1682) B56 PF01603.15 KEP65499.1 - 2.7e-157 523.5 11.0 3.3e-157 523.3 7.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sporozoite_P67 PF05642.6 KEP65499.1 - 6 4.5 10.0 8.6 4.0 6.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BSD PF03909.12 KEP65500.1 - 0.00037 20.1 0.7 0.057 13.1 0.0 3.2 3 0 0 3 3 3 2 BSD domain Cytochrom_C1 PF02167.10 KEP65502.1 - 4.9e-79 265.0 0.0 1.4e-78 263.5 0.0 1.7 2 0 0 2 2 2 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KEP65502.1 - 0.0013 18.8 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KEP65502.1 - 0.0077 17.0 0.0 0.019 15.7 0.0 1.8 1 0 0 1 1 1 1 Cytochrome c Asp PF00026.18 KEP65503.1 - 2.8e-68 230.4 0.0 3.6e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEP65503.1 - 7.9e-06 25.9 0.8 9.2e-05 22.4 0.0 2.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal DuffyBP_N PF12377.3 KEP65503.1 - 0.026 14.7 0.1 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 Duffy binding protein N terminal V-ATPase_G PF03179.10 KEP65505.1 - 4.9e-27 94.2 9.4 5.8e-27 94.0 6.5 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 KEP65505.1 - 0.0034 16.6 7.7 0.0042 16.3 5.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ADPrib_exo_Tox PF03496.9 KEP65505.1 - 0.0041 16.3 0.8 0.0046 16.1 0.6 1.2 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme DUF1186 PF06685.6 KEP65505.1 - 0.0067 15.6 1.3 0.0076 15.4 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1186) DUF1098 PF06497.6 KEP65505.1 - 0.021 14.8 1.4 0.79 9.8 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1098) PKK PF12474.3 KEP65505.1 - 0.025 14.3 6.1 0.045 13.4 4.1 1.5 1 1 0 1 1 1 0 Polo kinase kinase ATP-synt_B PF00430.13 KEP65505.1 - 0.046 13.5 10.0 0.043 13.6 5.9 1.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) HrpE PF06188.7 KEP65505.1 - 0.88 9.2 3.9 1 9.1 2.7 1.3 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E vATP-synt_E PF01991.13 KEP65505.1 - 1.6 7.9 11.9 3.2 6.9 8.2 1.4 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit RILP PF11461.3 KEP65505.1 - 2.4 8.3 6.2 0.65 10.1 0.9 2.1 1 1 1 2 2 2 0 Rab interacting lysosomal protein DegT_DnrJ_EryC1 PF01041.12 KEP65506.1 - 0.11 11.5 0.6 0.16 10.9 0.1 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family RepL PF05732.6 KEP65506.1 - 0.13 11.4 0.2 0.13 11.4 0.2 1.8 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) BSP_II PF05432.6 KEP65506.1 - 0.96 8.6 9.6 0.36 10.0 3.2 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 KEP65506.1 - 2.1 8.6 15.9 3.9 7.8 4.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 KEP65506.1 - 9.4 5.8 8.5 2.4 7.8 1.1 2.1 2 0 0 2 2 2 0 FAM176 family EutQ PF06249.7 KEP65507.1 - 0.066 12.7 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Beta-lactamase PF00144.19 KEP65509.1 - 1.8e-34 119.2 1.7 1.7e-31 109.4 0.2 3.2 3 0 0 3 3 3 2 Beta-lactamase ABC1 PF03109.11 KEP65509.1 - 3.2e-23 81.9 0.0 5.6e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 KEP65509.1 - 0.0077 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KEP65509.1 - 0.019 14.3 0.1 0.064 12.6 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Synaptobrevin PF00957.16 KEP65510.1 - 7.6e-13 47.8 0.0 1.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin G10 PF01125.12 KEP65512.1 - 2.4e-61 205.5 11.0 2.7e-61 205.3 7.6 1.0 1 0 0 1 1 1 1 G10 protein SHS2_Rpb7-N PF03876.12 KEP65513.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Macoilin PF09726.4 KEP65514.1 - 6.7 4.8 12.7 9.1 4.4 8.8 1.2 1 0 0 1 1 1 0 Transmembrane protein zf-DHHC PF01529.15 KEP65516.1 - 1.3e-22 79.9 21.7 5.3e-20 71.5 10.0 3.1 1 1 1 2 2 2 2 DHHC palmitoyltransferase AP2 PF00847.15 KEP65517.1 - 0.0038 17.3 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 AP2 domain TFIID-31kDa PF02291.10 KEP65518.1 - 0.00097 18.9 0.1 0.0023 17.6 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit DUF348 PF03990.9 KEP65518.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF348) Alpha-amylase PF00128.19 KEP65519.1 - 3.5e-25 89.0 0.3 1.7e-13 50.6 0.0 2.7 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KEP65519.1 - 2.2e-08 34.1 0.0 5.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_70 PF02324.11 KEP65519.1 - 0.33 8.6 0.0 3.1 5.4 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 Ebp2 PF05890.7 KEP65522.1 - 1.5e-31 109.7 23.7 1.9e-31 109.4 16.4 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Dynamitin PF04912.9 KEP65523.1 - 1.6e-34 119.3 2.7 1e-15 57.4 0.0 3.6 3 1 0 3 3 3 3 Dynamitin PG_binding_1 PF01471.13 KEP65523.1 - 0.068 13.1 0.0 0.26 11.2 0.0 2.1 1 0 0 1 1 1 0 Putative peptidoglycan binding domain IncA PF04156.9 KEP65523.1 - 2.5 7.6 15.4 1.7 8.2 4.7 2.6 2 1 1 3 3 3 0 IncA protein Spectrin PF00435.16 KEP65523.1 - 4.7 7.5 11.0 20 5.5 0.5 2.9 1 1 1 2 2 2 0 Spectrin repeat TPR_16 PF13432.1 KEP65525.1 - 2.3e-07 31.3 4.9 0.0024 18.5 0.1 5.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEP65525.1 - 3.8e-06 27.0 3.1 25 5.8 0.0 6.9 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP65525.1 - 5.5e-06 26.6 0.8 0.11 12.8 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KEP65525.1 - 0.0019 18.3 0.5 0.0065 16.5 0.4 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KEP65525.1 - 0.0058 16.4 2.1 4.6 7.4 0.5 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ACDC PF14733.1 KEP65526.1 - 1.7e-09 37.6 0.1 8.8e-06 25.7 0.0 2.6 2 1 0 2 2 2 2 AP2-coincident C-terminal PAP2_C PF14360.1 KEP65527.1 - 6.5e-06 26.3 22.2 0.00044 20.4 0.4 3.2 3 0 0 3 3 3 2 PAP2 superfamily C-terminal BCIP PF13862.1 KEP65527.1 - 0.29 10.5 0.0 0.53 9.7 0.0 1.3 1 0 0 1 1 1 0 p21-C-terminal region-binding protein PAP2 PF01569.16 KEP65527.1 - 4.1 7.0 13.3 8.7 6.0 1.3 2.9 2 1 0 2 2 2 0 PAP2 superfamily Peptidase_S9 PF00326.16 KEP65528.1 - 4e-30 104.6 0.0 9.2e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KEP65528.1 - 4.7e-09 36.4 1.1 2.8e-08 33.9 0.8 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP65528.1 - 4.4e-07 29.7 0.2 1.4e-06 28.1 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP65528.1 - 0.00087 18.9 0.0 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEP65528.1 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 KEP65528.1 - 0.18 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DLH PF01738.13 KEP65528.1 - 0.21 10.8 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family SET PF00856.23 KEP65529.1 - 1.6e-13 51.3 0.0 3.4e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KEP65529.1 - 0.0018 18.1 5.1 0.0018 18.1 3.5 2.3 2 0 0 2 2 2 1 MYND finger Pyr_redox_2 PF07992.9 KEP65530.1 - 1.4e-39 136.0 0.4 2.4e-39 135.3 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEP65530.1 - 3.9e-32 110.5 0.8 7.3e-32 109.6 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEP65530.1 - 3.9e-17 62.4 1.5 7.6e-16 58.2 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEP65530.1 - 2.3e-08 34.3 0.4 5.4e-06 26.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEP65530.1 - 3.2e-06 26.4 0.2 3.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEP65530.1 - 4.5e-06 25.4 1.3 0.019 13.4 0.3 3.2 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 KEP65530.1 - 0.00047 19.1 0.1 0.0019 17.1 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 KEP65530.1 - 0.00051 19.0 4.0 0.062 12.1 1.0 3.7 3 2 2 5 5 5 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KEP65530.1 - 0.00053 19.6 2.3 0.0017 18.0 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KEP65530.1 - 0.0035 16.2 5.6 0.17 10.6 0.1 2.5 1 1 1 2 2 2 2 FAD binding domain 2-Hacid_dh_C PF02826.14 KEP65530.1 - 0.023 13.8 2.0 0.13 11.3 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KEP65530.1 - 0.025 14.3 0.7 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KEP65530.1 - 0.027 14.4 3.5 0.066 13.2 2.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 KEP65530.1 - 0.048 13.3 0.1 0.62 9.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.1 KEP65530.1 - 0.064 13.5 0.3 4 7.7 0.1 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain EF-hand_1 PF00036.27 KEP65531.1 - 2.3e-13 48.3 2.2 3.3e-05 22.8 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEP65531.1 - 4.7e-12 44.7 0.7 4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KEP65531.1 - 6.6e-12 44.8 0.7 1.7e-05 24.3 0.0 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KEP65531.1 - 2.5e-11 42.3 1.0 2.1e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KEP65531.1 - 8.5e-11 41.8 0.0 5.9e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 KEP65531.1 - 0.035 13.7 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 EF hand FGGY_C PF02782.11 KEP65533.1 - 0.026 14.1 0.8 0.083 12.4 0.1 2.1 2 1 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain OmpH PF03938.9 KEP65533.1 - 0.14 12.1 6.4 0.23 11.3 4.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 KEP65533.1 - 2 7.3 6.7 3.1 6.7 4.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 YlqD PF11068.3 KEP65533.1 - 4.5 7.3 6.8 9.5 6.2 4.7 1.5 1 0 0 1 1 1 0 YlqD protein ProRS-C_1 PF09180.6 KEP65534.1 - 0.062 13.2 0.9 0.11 12.4 0.6 1.7 1 1 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal zf-RanBP PF00641.13 KEP65534.1 - 0.31 10.1 3.6 3.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Lactamase_B_2 PF12706.2 KEP65535.1 - 2e-13 50.3 0.0 2.2e-05 24.1 0.0 2.6 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEP65535.1 - 4.5e-09 36.2 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 KEP65535.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DNA_pol_A_exo1 PF01612.15 KEP65536.1 - 6.6e-40 136.4 0.1 9.3e-40 135.9 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 KEP65536.1 - 3.8e-08 32.9 0.1 1.3e-07 31.1 0.1 2.0 1 0 0 1 1 1 1 HRDC domain Glycos_transf_1 PF00534.15 KEP65538.1 - 1.6e-07 30.8 0.0 0.00022 20.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEP65538.1 - 0.041 14.0 0.1 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 P5-ATPase PF12409.3 KEP65538.1 - 0.42 10.4 1.2 20 5.0 0.7 2.4 2 0 0 2 2 2 0 P5-type ATPase cation transporter TPR_11 PF13414.1 KEP65541.1 - 1.4e-17 63.1 9.8 1e-06 28.2 0.3 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KEP65541.1 - 1.2e-09 37.3 2.1 0.028 14.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP65541.1 - 1.1e-06 28.0 2.3 0.56 10.2 0.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEP65541.1 - 0.03 14.1 1.8 0.048 13.4 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FeoB_C PF07664.7 KEP65541.1 - 0.21 11.0 3.2 0.37 10.2 2.2 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus TPR_12 PF13424.1 KEP65541.1 - 0.23 11.3 5.7 0.08 12.8 0.3 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEP65541.1 - 0.99 10.1 8.6 0.48 11.1 1.6 3.0 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEP65541.1 - 1.6 9.1 3.9 4 7.8 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4483 PF14825.1 KEP65542.1 - 0.00045 19.9 0.1 0.76 9.4 0.0 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4483) Mitofilin PF09731.4 KEP65544.1 - 0.41 9.2 12.8 0.49 9.0 8.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIF_alpha PF05793.7 KEP65544.1 - 1.5 7.0 29.5 2.3 6.5 20.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 KEP65544.1 - 3.7 6.0 5.5 4 5.9 3.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ndc1_Nup PF09531.5 KEP65544.1 - 4.3 5.6 7.7 4.9 5.4 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PITH PF06201.8 KEP65545.1 - 3.5e-20 72.3 0.0 1.2e-19 70.6 0.0 1.7 1 1 0 1 1 1 1 PITH domain IGPS PF00218.16 KEP65546.1 - 0.068 12.2 0.3 0.076 12.0 0.2 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase SlyX PF04102.7 KEP65546.1 - 0.086 13.2 2.1 0.13 12.6 0.6 1.9 1 1 1 2 2 2 0 SlyX CAF-1_p150 PF11600.3 KEP65547.1 - 2.2 7.5 6.8 4.4 6.6 4.7 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal H_lectin PF09458.5 KEP65549.1 - 0.0048 16.5 0.1 0.087 12.4 0.0 3.0 3 0 0 3 3 3 1 H-type lectin domain TSP_1 PF00090.14 KEP65549.1 - 0.024 14.7 47.0 0.015 15.4 4.8 6.6 6 0 0 6 6 6 0 Thrombospondin type 1 domain CMS1 PF14617.1 KEP65549.1 - 1.4 7.9 2.0 0.94 8.4 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit NUDIX PF00293.23 KEP65550.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain EF-hand_1 PF00036.27 KEP65551.1 - 1.9e-33 111.1 16.6 3.5e-09 35.2 0.8 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP65551.1 - 1.8e-28 98.4 9.3 8e-16 57.9 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP65551.1 - 1.5e-26 89.8 10.6 3.1e-09 35.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KEP65551.1 - 2.7e-25 87.7 14.9 5.5e-14 51.5 0.7 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KEP65551.1 - 1e-19 68.9 18.4 3.9e-05 22.7 0.3 4.5 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 KEP65551.1 - 1.2e-13 50.7 0.1 5.9e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEP65551.1 - 4.6e-08 32.7 6.5 0.01 15.5 0.4 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEP65551.1 - 0.0039 17.1 0.1 1.4 8.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF21 PF01595.15 KEP65551.1 - 0.048 12.9 1.4 0.41 9.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF853 PF05872.7 KEP65551.1 - 0.056 11.7 0.1 0.5 8.6 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) SRI PF08236.6 KEP65551.1 - 0.058 13.3 0.2 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain FlgD PF03963.9 KEP65551.1 - 0.068 13.2 0.1 0.22 11.6 0.0 1.9 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region TBPIP PF07106.8 KEP65551.1 - 0.076 12.5 0.9 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TerB PF05099.8 KEP65551.1 - 0.084 12.6 1.4 2.5 7.8 0.1 2.5 2 1 0 2 2 2 0 Tellurite resistance protein TerB Toprim_2 PF13155.1 KEP65551.1 - 0.087 13.1 2.1 11 6.4 0.1 2.5 1 1 1 2 2 2 0 Toprim-like Caleosin PF05042.8 KEP65551.1 - 0.12 11.8 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein MgtE_N PF03448.12 KEP65551.1 - 0.22 11.8 4.0 0.2 12.0 0.5 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain EF-hand_10 PF14788.1 KEP65551.1 - 0.34 10.5 3.9 1.5 8.5 0.7 2.9 3 0 0 3 3 3 0 EF hand Excalibur PF05901.6 KEP65551.1 - 4.1 7.8 5.2 4.7 7.6 0.1 2.6 2 1 0 3 3 3 0 Excalibur calcium-binding domain Peptidase_C12 PF01088.16 KEP65552.1 - 5.8e-59 198.8 0.0 1e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3499 PF12005.3 KEP65552.1 - 0.0092 16.1 0.6 0.026 14.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3499) DUF1840 PF08895.6 KEP65552.1 - 0.11 12.5 1.9 0.22 11.5 0.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) VHP PF02209.14 KEP65552.1 - 0.25 11.0 5.2 6.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Villin headpiece domain CAF1C_H4-bd PF12265.3 KEP65553.1 - 3.1e-24 84.6 0.1 7.9e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 KEP65553.1 - 2.1e-15 55.9 9.8 5.4e-05 22.9 0.6 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DASH_Dam1 PF08653.5 KEP65554.1 - 0.18 11.5 0.1 7.1 6.4 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 Methyltransf_3 PF01596.12 KEP65555.1 - 4.5e-13 48.7 0.0 0.00023 20.2 0.0 3.4 3 0 0 3 3 3 3 O-methyltransferase Methyltransf_24 PF13578.1 KEP65555.1 - 2.5e-08 34.7 0.0 0.004 17.9 0.1 3.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KEP65555.1 - 0.0082 16.1 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 KEP65556.1 - 2.2e-06 27.9 0.0 0.072 13.4 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain UPF0167 PF03691.9 KEP65556.1 - 0.52 9.7 5.4 0.95 8.8 3.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) CPW_WPC PF09717.5 KEP65560.1 - 1.3e-81 269.1 43.3 4.4e-17 62.4 2.9 5.3 5 0 0 5 5 5 5 Plasmodium falciparum domain of unknown function (CPW_WPC) PsbP PF01789.11 KEP65560.1 - 0.14 11.5 0.0 38 3.6 0.0 3.3 4 0 0 4 4 4 0 PsbP Tom5 PF10642.4 KEP65560.1 - 3.2 7.4 5.3 34 4.1 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase SLBP_RNA_bind PF15247.1 KEP65561.1 - 1e-22 79.6 5.2 3.3e-22 78.0 3.0 2.2 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Symplekin_C PF12295.3 KEP65562.1 - 3.2e-47 160.8 1.1 5.6e-47 160.0 0.1 1.9 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal Thioredoxin PF00085.15 KEP65564.1 - 8.8e-27 92.8 0.0 1.4e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEP65564.1 - 4.9e-07 29.9 0.0 4.8e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEP65564.1 - 8.7e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 KEP65564.1 - 0.00025 20.8 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEP65564.1 - 0.00036 20.5 0.1 0.029 14.4 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KEP65564.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain DUF3789 PF12664.2 KEP65564.1 - 0.061 12.6 10.8 0.087 12.1 6.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) TraF PF13728.1 KEP65564.1 - 0.1 12.0 0.0 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 F plasmid transfer operon protein PAP2 PF01569.16 KEP65565.1 - 1e-21 76.9 3.9 1.6e-21 76.3 2.7 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KEP65565.1 - 0.0079 16.4 4.2 0.21 11.8 2.9 2.6 1 1 0 1 1 1 1 PAP2 superfamily C-terminal SAND PF01342.16 KEP65565.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SAND domain Virul_fac_BrkB PF03631.10 KEP65565.1 - 1.4 8.2 6.3 0.2 11.0 0.4 2.0 2 0 0 2 2 2 0 Virulence factor BrkB PKD_channel PF08016.7 KEP65566.1 - 1.3e-11 43.6 61.0 1.8e-09 36.5 11.6 5.1 5 1 0 5 5 5 4 Polycystin cation channel Bacillus_HBL PF05791.6 KEP65566.1 - 0.09 12.1 4.8 0.16 11.2 3.3 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CDC50 PF03381.10 KEP65567.1 - 6.2e-30 104.3 0.0 9.8e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family AAA PF00004.24 KEP65568.1 - 3.2e-30 105.0 0.0 7.1e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KEP65568.1 - 0.0026 17.2 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KEP65568.1 - 0.031 14.4 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEP65568.1 - 0.035 13.8 0.0 0.098 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 KEP65568.1 - 0.71 8.9 0.0 1.2 8.2 0.0 1.3 1 0 0 1 1 1 0 KaiC PIF1 PF05970.9 KEP65568.1 - 9.6 5.0 0.0 16 4.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase O-antigen_lig PF13425.1 KEP65572.1 - 0.21 11.5 1.9 1.6 8.6 0.3 2.2 2 0 0 2 2 2 0 O-antigen ligase like membrane protein MARVEL PF01284.18 KEP65572.1 - 0.54 10.0 4.4 3.5 7.4 0.3 2.9 3 0 0 3 3 3 0 Membrane-associating domain Bactofilin PF04519.8 KEP65572.1 - 0.59 10.1 4.1 15 5.6 0.2 2.4 1 1 1 2 2 2 0 Polymer-forming cytoskeletal PCNA_N PF00705.13 KEP65574.1 - 5.6e-45 151.9 4.9 5.6e-45 151.9 3.4 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KEP65574.1 - 1.6e-29 102.4 0.1 3.8e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KEP65574.1 - 1.7e-07 30.6 0.2 2.4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Rad9 Nop PF01798.13 KEP65575.1 - 1.4e-51 173.7 0.1 3.7e-51 172.3 0.1 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KEP65575.1 - 2.7e-20 71.9 0.0 4.6e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KEP65575.1 - 2.9e-14 52.9 0.1 1.6e-13 50.5 0.0 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DDHD PF02862.12 KEP65575.1 - 0.61 9.8 6.1 1.5 8.5 4.2 1.8 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KEP65575.1 - 2.7 7.8 18.0 5.1 6.9 12.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-RING_2 PF13639.1 KEP65576.1 - 2.7e-10 39.8 3.2 7.5e-10 38.4 2.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEP65576.1 - 2.6e-08 33.7 4.0 2.6e-08 33.7 2.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP65576.1 - 9.5e-08 31.5 2.5 3.1e-07 29.9 1.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP65576.1 - 7.7e-07 29.1 1.1 2.5e-06 27.4 0.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEP65576.1 - 4e-05 23.1 1.1 4e-05 23.1 0.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP65576.1 - 4.8e-05 23.0 2.9 4.8e-05 23.0 2.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEP65576.1 - 0.00012 21.8 0.9 0.00023 20.9 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KEP65576.1 - 0.0006 19.4 1.8 0.0014 18.3 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEP65576.1 - 0.00089 19.0 3.9 0.0026 17.5 2.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KEP65576.1 - 0.0033 17.3 2.0 0.011 15.7 1.4 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 KEP65576.1 - 0.14 12.1 2.7 0.39 10.7 1.9 1.8 1 0 0 1 1 1 0 RING-variant domain Atg14 PF10186.4 KEP65576.1 - 0.47 9.3 27.6 0.011 14.6 12.3 2.5 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KEP65576.1 - 5.2 4.8 6.4 9.6 3.9 4.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ACOX PF01756.14 KEP65577.1 - 1.1e-33 116.2 0.0 1.9e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KEP65577.1 - 1.1e-16 61.2 0.0 2.6e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KEP65577.1 - 1.7e-09 37.0 0.1 3.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain FBPase PF00316.15 KEP65578.1 - 6.8e-122 406.3 0.0 8e-122 406.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase ABC2_membrane PF01061.19 KEP65580.1 - 4.5e-32 110.9 13.7 6.1e-32 110.4 9.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KEP65580.1 - 3.5e-23 82.3 0.0 5.9e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEP65580.1 - 1.4e-09 38.3 0.0 0.00028 20.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KEP65580.1 - 1.8e-07 30.5 8.6 1.8e-07 30.5 6.0 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.1 KEP65580.1 - 0.0001 22.3 1.6 0.00011 22.1 0.0 1.9 3 0 0 3 3 1 1 AAA ATPase domain AAA_29 PF13555.1 KEP65580.1 - 0.00079 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KEP65580.1 - 0.00083 18.8 0.0 0.017 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEP65580.1 - 0.0025 17.9 0.1 0.007 16.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain DUF258 PF03193.11 KEP65580.1 - 0.0042 16.2 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KEP65580.1 - 0.006 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 KEP65580.1 - 0.0085 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 KEP65580.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEP65580.1 - 0.018 14.7 0.2 0.067 12.9 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KEP65580.1 - 0.018 14.4 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KEP65580.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KEP65580.1 - 0.022 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 KEP65580.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KEP65580.1 - 0.026 14.3 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEP65580.1 - 0.029 15.2 0.0 0.067 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEP65580.1 - 0.034 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KEP65580.1 - 0.042 13.0 0.0 0.56 9.4 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KEP65580.1 - 0.068 12.8 0.1 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KEP65580.1 - 0.12 12.6 0.1 0.36 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEP65580.1 - 0.18 11.1 0.2 0.4 10.0 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 KEP65580.1 - 0.2 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KEP65580.1 - 0.22 11.3 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA PF00004.24 KEP65580.1 - 0.25 11.5 0.3 1.2 9.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cpn60_TCP1 PF00118.19 KEP65581.1 - 6.2e-126 420.8 10.6 7.3e-126 420.6 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tctex-1 PF03645.8 KEP65582.1 - 7.5e-29 99.5 4.5 9.2e-29 99.2 3.1 1.1 1 0 0 1 1 1 1 Tctex-1 family Methyltrans_RNA PF04452.9 KEP65582.1 - 0.06 12.4 0.3 0.071 12.2 0.2 1.1 1 0 0 1 1 1 0 RNA methyltransferase Sporozoite_P67 PF05642.6 KEP65583.1 - 0.19 9.5 9.9 0.32 8.7 6.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glutaredoxin PF00462.19 KEP65584.1 - 1.8e-12 47.0 0.0 2.9e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Glutaredoxin Methyltransf_11 PF08241.7 KEP65585.1 - 1e-12 48.3 0.0 2.3e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP65585.1 - 3.4e-08 33.3 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP65585.1 - 4.9e-06 26.2 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP65585.1 - 0.00039 20.8 0.0 0.0009 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP65585.1 - 0.00076 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEP65585.1 - 0.0017 17.5 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0561 PF10573.4 KEP65585.1 - 0.056 13.2 0.0 0.056 13.2 0.0 2.6 1 1 0 2 2 2 0 Uncharacterised protein family UPF0561 DLIC PF05783.6 KEP65586.1 - 7e-21 74.4 4.0 8.7e-19 67.5 0.1 3.6 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 KEP65586.1 - 0.048 12.3 0.0 0.067 11.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Peptidase_M42 PF05343.9 KEP65586.1 - 0.072 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase SPO22 PF08631.5 KEP65586.1 - 0.11 11.5 0.3 0.27 10.2 0.1 1.6 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like LSM PF01423.17 KEP65587.1 - 4.8e-20 70.8 0.0 5.7e-20 70.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2749 PF10907.3 KEP65588.1 - 2.9 7.8 6.5 4.9 7.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Sybindin PF04099.7 KEP65590.1 - 1.1e-22 80.2 0.0 2e-22 79.4 0.0 1.4 1 1 0 1 1 1 1 Sybindin-like family Pex2_Pex12 PF04757.9 KEP65591.1 - 1.2e-17 64.1 0.0 7.8e-17 61.4 0.0 2.3 2 1 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 KEP65591.1 - 2.8e-05 23.7 3.9 5.8e-05 22.6 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP65591.1 - 4.5e-05 23.3 6.7 4.5e-05 23.3 4.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP65591.1 - 0.00084 19.1 6.8 0.0017 18.1 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEP65591.1 - 1.7 8.3 5.2 3.6 7.3 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Thioredoxin PF00085.15 KEP65592.1 - 4.7e-12 45.5 0.0 1.4e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 KEP65592.1 - 3.6e-10 39.9 1.3 7e-07 29.2 1.6 3.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KEP65592.1 - 0.00036 20.6 0.1 0.0039 17.3 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain KaiB PF07689.7 KEP65592.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiB domain Ribul_P_3_epim PF00834.14 KEP65593.1 - 4.9e-65 218.4 0.0 5.7e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 KEP65593.1 - 0.028 13.6 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 PcrB family YCII PF03795.9 KEP65594.1 - 0.0019 18.3 0.0 0.4 10.8 0.0 2.6 2 0 0 2 2 2 2 YCII-related domain Hydrolase PF00702.21 KEP65595.1 - 1.1e-12 48.8 0.1 7.7e-10 39.5 0.1 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP65595.1 - 3.3e-12 46.9 0.0 2.1e-11 44.3 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEP65595.1 - 4e-11 42.3 0.3 2.3e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KEP65595.1 - 6.7e-06 25.9 0.0 1.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEP65595.1 - 0.0017 18.0 0.0 0.0089 15.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Elongin_A PF06881.6 KEP65596.1 - 0.6 10.5 3.7 0.82 10.0 2.6 1.3 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A AP2 PF00847.15 KEP65597.1 - 7.2e-08 32.4 8.4 1.3e-06 28.4 0.1 4.3 4 0 0 4 4 4 2 AP2 domain Pkinase PF00069.20 KEP65598.1 - 3.8e-34 118.0 0.0 4.8e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65598.1 - 2.7e-14 52.8 0.0 3.4e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP65598.1 - 5.4e-06 26.3 0.1 0.0029 17.3 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEP65598.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEP65598.1 - 0.17 11.2 0.1 0.36 10.1 0.0 1.5 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL ACDC PF14733.1 KEP65599.1 - 1.4e-20 73.1 0.1 2.2e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 KEP65599.1 - 8.6e-11 41.8 0.1 8.6e-11 41.8 0.1 4.3 5 0 0 5 5 5 2 AP2 domain tRNA_U5-meth_tr PF05958.6 KEP65600.1 - 0.0012 17.5 0.0 0.58 8.7 0.0 2.7 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.11 KEP65600.1 - 0.0039 16.7 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.15 KEP65600.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 KEP65600.1 - 0.013 14.9 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KEP65600.1 - 0.024 15.1 0.0 0.078 13.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF4611 PF15387.1 KEP65601.1 - 0.089 12.9 0.3 0.089 12.9 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF4201 PF13870.1 KEP65601.1 - 0.29 10.5 2.9 0.35 10.2 0.6 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Herpes_UL25 PF01499.11 KEP65601.1 - 0.97 7.6 4.0 1 7.6 0.4 2.0 1 1 1 2 2 2 0 Herpesvirus UL25 family AMP-binding PF00501.23 KEP65602.1 - 9.1e-74 248.3 0.0 1.5e-73 247.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme DUF1361 PF07099.6 KEP65603.1 - 0.0094 15.7 0.1 0.023 14.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1361) Baculo_11_kDa PF06143.6 KEP65604.1 - 1.1 8.6 3.5 0.78 9.1 0.2 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family Cation_ATPase_C PF00689.16 KEP65604.1 - 1.5 8.3 13.7 1.3 8.4 2.2 2.1 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus VRR_NUC PF08774.6 KEP65605.1 - 6.1e-13 48.6 0.0 2.1e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain AKAP28 PF14469.1 KEP65606.1 - 7.1e-08 32.0 0.0 0.00059 19.4 0.0 2.5 2 0 0 2 2 2 2 28 kDa A-kinase anchor EF-hand_7 PF13499.1 KEP65606.1 - 0.035 14.2 0.0 0.71 10.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 KEP65606.1 - 0.042 13.1 0.0 0.55 9.6 0.0 2.6 2 0 0 2 2 2 0 EF hand Methyltransf_11 PF08241.7 KEP65607.1 - 8.2e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP65607.1 - 2.2e-14 53.3 0.0 3.8e-14 52.5 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP65607.1 - 2e-13 50.3 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP65607.1 - 2.7e-13 50.2 0.0 2.5e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEP65607.1 - 3.6e-13 49.1 0.0 4.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEP65607.1 - 3e-12 46.7 0.0 1.1e-11 44.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP65607.1 - 1.1e-11 45.3 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP65607.1 - 1.1e-08 35.0 0.0 3.6e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KEP65607.1 - 2.8e-06 26.8 0.0 6.5e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 KEP65607.1 - 4.5e-05 22.9 0.0 7.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 KEP65607.1 - 0.00074 19.2 0.0 0.0014 18.2 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.14 KEP65607.1 - 0.0073 15.8 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 KEP65607.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KEP65607.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 KEP65607.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) SNARE PF05739.14 KEP65608.1 - 1e-17 63.5 4.9 1e-17 63.5 3.4 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KEP65608.1 - 6.6e-06 26.2 1.4 6.6e-06 26.2 1.0 2.5 2 1 0 2 2 2 1 Syntaxin DUF912 PF06024.7 KEP65608.1 - 0.12 12.3 1.6 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1469 PF07332.6 KEP65608.1 - 0.28 10.9 1.5 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF2383 PF09537.5 KEP65608.1 - 0.46 10.7 3.8 6.4 7.0 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) Adaptin_binding PF10199.4 KEP65608.1 - 1.3 9.3 9.1 7.3 6.8 1.7 2.4 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 LTXXQ PF07813.7 KEP65608.1 - 4.2 7.8 11.6 0.59 10.6 0.7 2.7 3 0 0 3 3 3 0 LTXXQ motif family protein Synaptobrevin PF00957.16 KEP65608.1 - 4.2 7.0 6.0 5.1 6.7 1.0 2.5 2 0 0 2 2 2 0 Synaptobrevin DUF2019 PF09450.5 KEP65608.1 - 6.6 6.6 7.5 0.72 9.7 1.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) Reo_sigmaC PF04582.7 KEP65609.1 - 3.5e-06 26.4 0.1 4.2e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Kinetocho_Slk19 PF12709.2 KEP65609.1 - 0.052 13.6 0.7 8.8 6.4 0.0 2.5 1 1 1 2 2 2 0 Central kinetochore-associated ADIP PF11559.3 KEP65609.1 - 1.6 8.6 11.0 0.051 13.4 2.7 2.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 KEP65609.1 - 3.7 7.1 9.8 0.27 10.7 1.2 2.7 2 1 1 3 3 3 0 Septum formation initiator SlyX PF04102.7 KEP65609.1 - 4.1 7.8 8.8 0.79 10.1 0.9 3.1 3 1 0 3 3 3 0 SlyX TMF_DNA_bd PF12329.3 KEP65609.1 - 7.2 6.5 9.0 9.6 6.0 1.6 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0197 PF05251.7 KEP65614.1 - 8.5e-13 48.4 4.5 1.1e-12 47.9 3.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) TMEM238 PF15125.1 KEP65614.1 - 0.09 12.7 0.5 0.09 12.7 0.4 1.7 2 0 0 2 2 2 0 TMEM238 protein family ATPase_gene1 PF09527.5 KEP65614.1 - 0.77 9.6 5.0 10 5.9 0.2 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Class_IIIsignal PF04021.7 KEP65614.1 - 2 8.2 5.6 0.25 11.1 0.8 1.9 2 1 0 2 2 2 0 Class III signal peptide Synaptobrevin PF00957.16 KEP65615.1 - 4.9e-26 90.1 0.0 6.6e-26 89.7 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEP65615.1 - 1.2e-06 28.0 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SecE PF00584.15 KEP65615.1 - 0.012 15.1 0.2 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Herpes_UL6 PF01763.11 KEP65615.1 - 0.041 12.0 0.1 0.055 11.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like COG2 PF06148.6 KEP65615.1 - 0.12 12.2 0.7 0.44 10.4 0.3 2.0 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 EMP24_GP25L PF01105.19 KEP65615.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Maf1 PF09174.5 KEP65616.1 - 8.6e-19 68.0 0.0 7.6e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 Maf1 regulator SWIB PF02201.13 KEP65617.1 - 0.025 14.2 0.0 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 SWIB/MDM2 domain MCD PF05292.6 KEP65617.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) Med11 PF10280.4 KEP65617.1 - 0.42 10.6 3.9 0.89 9.6 2.7 1.4 1 0 0 1 1 1 0 Mediator complex protein SPG48 PF14764.1 KEP65620.1 - 3.6e-62 210.3 7.0 1.8e-56 191.6 1.3 2.6 3 0 0 3 3 3 2 AP-5 complex subunit, vesicle trafficking Ycf1 PF05758.7 KEP65620.1 - 5.8 4.4 2.6 8.6 3.9 1.8 1.1 1 0 0 1 1 1 0 Ycf1 Nucleo_P87 PF07267.6 KEP65620.1 - 6 5.4 3.8 12 4.3 2.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ku PF02735.11 KEP65621.1 - 6.5e-15 55.0 0.0 4.6e-14 52.2 0.0 2.1 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KEP65621.1 - 1.6e-08 34.2 0.0 3.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KEP65621.1 - 0.21 12.1 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Pex14_N PF04695.8 KEP65622.1 - 8.4e-13 48.5 0.0 8.4e-13 48.5 0.0 5.1 5 0 0 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PUB PF09409.5 KEP65622.1 - 0.00034 20.2 0.0 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 PUB domain Drf_FH1 PF06346.7 KEP65622.1 - 0.002 17.6 41.3 0.002 17.6 28.6 3.6 3 1 1 4 4 4 1 Formin Homology Region 1 Pacs-1 PF10254.4 KEP65623.1 - 0.0069 15.0 3.9 0.008 14.8 2.7 1.1 1 0 0 1 1 1 1 PACS-1 cytosolic sorting protein SR-25 PF10500.4 KEP65623.1 - 5.8 6.3 13.5 6.8 6.1 9.0 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC27 PF09507.5 KEP65623.1 - 7.9 5.5 12.4 9.9 5.2 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ribosomal_L7Ae PF01248.21 KEP65625.1 - 9.5e-06 25.0 1.0 3.7e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RrnaAD PF00398.15 KEP65626.1 - 1.6e-51 174.8 0.0 2.2e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KEP65626.1 - 2.1e-08 34.2 0.1 4.3e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP65626.1 - 2.4e-07 30.4 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP65626.1 - 1.8e-05 25.3 0.0 3.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP65626.1 - 3.1e-05 24.3 0.0 0.0001 22.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEP65626.1 - 3.6e-05 23.2 0.0 5.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEP65626.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KEP65626.1 - 0.00035 21.0 0.0 0.00069 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP65626.1 - 0.00061 20.0 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP65626.1 - 0.0025 17.5 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEP65626.1 - 0.0049 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 KEP65626.1 - 0.0072 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.14 KEP65626.1 - 0.012 15.1 0.1 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KEP65626.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GAS PF13851.1 KEP65628.1 - 2.5e-35 121.5 25.7 2.5e-35 121.5 17.8 3.3 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding LRR_4 PF12799.2 KEP65629.1 - 9.3e-14 50.6 1.0 6.9e-05 22.3 0.0 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEP65629.1 - 0.0082 16.1 2.5 1.2 9.3 0.3 3.3 2 1 1 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.1 KEP65629.1 - 0.0087 15.7 8.0 0.054 13.2 0.7 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KEP65629.1 - 0.35 11.0 10.2 3.5 8.0 0.2 4.9 3 1 0 3 3 3 0 Leucine Rich Repeat PHF5 PF03660.9 KEP65630.1 - 1.9e-49 166.1 12.8 2.1e-49 166.0 8.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 KEP65630.1 - 2.3 5.7 9.5 2.5 5.6 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.2 KEP65630.1 - 3.3 7.6 17.9 8.8 6.2 3.4 2.8 1 1 1 2 2 2 0 Double zinc ribbon PepSY_TM_3 PF13706.1 KEP65631.1 - 3 7.3 7.2 5.5 6.4 5.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix zf-CCCH PF00642.19 KEP65632.1 - 3.3e-08 33.0 13.6 0.0011 18.6 0.7 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 KEP65634.1 - 4.7e-11 42.1 14.4 0.00012 21.8 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Hira PF07569.6 KEP65634.1 - 0.21 10.7 0.1 0.5 9.5 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split Ribosomal_L10 PF00466.15 KEP65635.1 - 0.00056 19.7 0.1 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L10 Snf7 PF03357.16 KEP65636.1 - 1.2e-28 99.5 5.9 1.9e-28 98.9 4.1 1.2 1 0 0 1 1 1 1 Snf7 Mito_carr PF00153.22 KEP65637.1 - 6.2e-55 182.9 4.1 4.4e-19 67.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial20 PF08256.6 KEP65637.1 - 0.68 10.4 3.0 3.7 8.1 0.0 3.1 3 0 0 3 3 3 0 Aurein-like antibiotic peptide zf-C3HC4_2 PF13923.1 KEP65638.1 - 1.7e-07 31.1 9.8 3.3e-07 30.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP65638.1 - 2.7e-07 30.2 10.5 5.4e-07 29.3 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEP65638.1 - 4.2e-06 26.3 9.0 9.6e-06 25.2 6.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEP65638.1 - 5.1e-06 26.2 6.2 1.6e-05 24.6 4.4 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KEP65638.1 - 0.00016 21.7 3.2 0.00035 20.6 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP65638.1 - 0.0002 20.9 8.7 0.00043 19.8 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP65638.1 - 0.00021 20.8 10.4 0.00043 19.9 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEP65638.1 - 0.0056 16.4 3.3 0.012 15.4 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 KEP65638.1 - 0.02 14.3 0.8 0.039 13.4 0.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KEP65638.1 - 0.021 14.5 4.6 0.17 11.6 2.8 2.5 1 1 1 2 2 2 0 RING-type zinc-finger Pex2_Pex12 PF04757.9 KEP65638.1 - 0.077 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region zf-RING_6 PF14835.1 KEP65638.1 - 0.52 10.1 5.4 1.4 8.7 3.7 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Ras PF00071.17 KEP65639.1 - 3.3e-51 172.8 0.0 4.1e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP65639.1 - 8.6e-16 58.5 0.0 1.7e-15 57.5 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KEP65639.1 - 4.9e-14 51.9 0.0 6.6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEP65639.1 - 3.8e-05 22.9 0.0 4.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 KEP65639.1 - 0.00083 19.5 0.2 0.0053 16.9 0.2 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 KEP65639.1 - 0.0052 15.5 0.1 0.47 9.0 0.0 2.9 2 1 1 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KEP65639.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP65639.1 - 0.018 14.4 0.7 0.45 9.9 0.5 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KEP65639.1 - 0.024 14.7 0.1 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KEP65639.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEP65639.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 KEP65639.1 - 0.092 11.7 0.1 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 KEP65639.1 - 0.098 12.1 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 KEP65639.1 - 0.11 11.3 0.1 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.12 KEP65639.1 - 0.12 11.9 0.1 7.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 KEP65639.1 - 0.15 11.7 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KEP65639.1 - 0.16 11.6 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Prefoldin_2 PF01920.15 KEP65641.1 - 2.6e-15 56.0 7.5 3.1e-15 55.8 4.8 1.4 1 1 0 1 1 1 1 Prefoldin subunit Nup54 PF13874.1 KEP65641.1 - 0.0087 15.7 2.1 0.0087 15.7 1.5 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Ig_J_chain PF15097.1 KEP65641.1 - 0.061 12.9 0.1 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Immunoglobulin J chain HR1 PF02185.11 KEP65641.1 - 0.071 12.8 9.8 0.58 9.9 1.8 2.9 1 1 2 3 3 3 0 Hr1 repeat DUF4404 PF14357.1 KEP65641.1 - 0.081 13.3 0.9 0.081 13.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CorA PF01544.13 KEP65641.1 - 0.13 11.2 4.5 0.17 10.9 3.1 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin_3 PF13758.1 KEP65641.1 - 0.25 11.1 6.2 0.22 11.3 1.4 2.6 1 1 1 2 2 2 0 Prefoldin subunit PilJ PF13675.1 KEP65641.1 - 0.29 11.4 4.2 3 8.1 0.5 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 KEP65641.1 - 0.6 9.9 8.4 4.8 6.9 1.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KEP65641.1 - 0.7 9.7 3.6 1.8 8.3 0.2 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.12 KEP65641.1 - 0.72 9.5 9.9 8.4 6.0 0.9 2.7 1 1 1 2 2 2 0 Prefoldin subunit DUF4164 PF13747.1 KEP65641.1 - 0.73 9.9 9.1 1.8 8.7 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF3571 PF12095.3 KEP65641.1 - 0.94 9.7 4.3 1.2 9.3 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) Syntaxin PF00804.20 KEP65641.1 - 0.99 9.5 10.9 1.1 9.4 2.1 2.4 1 1 1 2 2 2 0 Syntaxin DUF3166 PF11365.3 KEP65641.1 - 1.1 9.7 8.1 2.2 8.8 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) ATP-synt_B PF00430.13 KEP65641.1 - 1.7 8.4 7.0 0.73 9.6 1.3 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) GAS PF13851.1 KEP65641.1 - 1.8 7.6 11.5 3.2 6.9 2.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KxDL PF10241.4 KEP65641.1 - 2 8.3 6.7 0.29 11.0 1.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF1319 PF07028.6 KEP65641.1 - 2.1 8.5 7.0 6.3 7.0 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) CDC37_N PF03234.9 KEP65641.1 - 2.7 8.2 8.4 4.2 7.6 5.8 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Phage_GP20 PF06810.6 KEP65641.1 - 4.3 6.7 11.9 3.5 7.0 2.2 2.2 2 1 0 2 2 2 0 Phage minor structural protein GP20 HrpB7 PF09486.5 KEP65641.1 - 5.9 6.7 10.1 0.5 10.2 3.1 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2968 PF11180.3 KEP65641.1 - 6.1 6.1 13.1 0.85 8.9 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FliJ PF02050.11 KEP65641.1 - 7.9 6.5 13.2 4.8 7.2 1.0 2.4 2 1 0 2 2 2 0 Flagellar FliJ protein DUF2981 PF11200.3 KEP65642.1 - 1.8e-14 53.5 0.3 1.8e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2981) Tetraspannin PF00335.15 KEP65642.1 - 7.2 5.8 15.7 0.13 11.5 5.6 1.8 2 0 0 2 2 2 0 Tetraspanin family KOW PF00467.24 KEP65643.1 - 8.3e-08 31.6 4.0 8.3e-08 31.6 2.8 2.0 2 1 0 2 2 2 1 KOW motif Methyltrans_RNA PF04452.9 KEP65643.1 - 0.012 14.6 0.8 0.017 14.2 0.5 1.2 1 0 0 1 1 1 0 RNA methyltransferase TP2 PF01254.13 KEP65643.1 - 2.7 8.3 10.0 1.1 9.5 3.9 1.9 1 1 1 2 2 2 0 Nuclear transition protein 2 Glyoxalase PF00903.20 KEP65644.1 - 7e-39 132.7 0.0 1.1e-19 70.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEP65644.1 - 3.8e-30 104.6 0.3 3.4e-14 53.3 0.1 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KEP65644.1 - 5.1e-15 55.4 0.0 1.2e-06 28.5 0.0 3.4 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KEP65644.1 - 0.00084 19.2 0.0 0.076 12.9 0.0 2.5 2 1 0 2 2 2 1 Glyoxalase-like domain DUF3081 PF11280.3 KEP65644.1 - 0.0016 17.9 0.0 2 7.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3081) CppA_N PF14506.1 KEP65644.1 - 0.093 12.4 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal Toxin_67 PF15545.1 KEP65644.1 - 0.1 12.5 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Putative toxin 67 MFS_1 PF07690.11 KEP65645.1 - 9.5e-09 34.4 30.5 3.8e-07 29.1 19.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 KEP65645.1 - 1.5 7.3 0.0 1.5 7.3 0.0 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Condensation PF00668.15 KEP65646.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Condensation domain CarbpepA_inh PF02977.10 KEP65647.1 - 0.017 14.7 2.4 0.092 12.3 2.0 2.1 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor DUF904 PF06005.7 KEP65648.1 - 0.026 14.8 2.1 0.026 14.8 1.5 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF904) TSC22 PF01166.13 KEP65648.1 - 0.06 13.3 2.5 0.82 9.6 0.0 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.4 KEP65648.1 - 0.24 11.2 11.7 3 7.6 5.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.8 KEP65648.1 - 1.2 9.1 8.3 5.8 6.8 0.1 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HAUS6_N PF14661.1 KEP65648.1 - 3.5 6.8 12.9 3.5 6.9 8.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 KEP65648.1 - 6 5.8 14.5 2.3 7.1 8.1 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF3035 PF11233.3 KEP65648.1 - 6.1 6.8 6.9 9.4 6.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3035) Exonuc_VII_L PF02601.10 KEP65648.1 - 8 5.5 8.9 11 5.1 6.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_2 PF13639.1 KEP65649.1 - 1.7e-11 43.7 8.1 2.9e-11 43.0 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEP65649.1 - 5.1e-07 29.7 4.4 9.6e-07 28.8 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEP65649.1 - 6.7e-07 28.9 6.2 1.1e-06 28.2 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEP65649.1 - 1.5e-06 27.7 8.8 2.4e-06 27.0 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP65649.1 - 7.1e-06 25.9 8.1 1.3e-05 25.1 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP65649.1 - 1.7e-05 24.3 5.9 3e-05 23.5 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 KEP65649.1 - 0.0028 17.4 2.1 0.0053 16.5 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-Apc11 PF12861.2 KEP65649.1 - 0.0079 16.0 2.9 0.016 15.0 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEP65649.1 - 0.037 13.6 5.4 0.074 12.6 3.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 KEP65649.1 - 0.1 12.4 0.6 0.19 11.5 0.4 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 KEP65649.1 - 0.44 10.5 5.6 1 9.3 3.8 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KEP65649.1 - 1.7 8.7 8.2 3.1 7.9 5.7 1.4 1 0 0 1 1 1 0 RING-variant domain ubiquitin PF00240.18 KEP65650.1 - 3.6e-17 61.5 0.0 2.5e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family UN_NPL4 PF11543.3 KEP65650.1 - 0.0095 16.1 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Crinivirus_P26 PF07416.6 KEP65650.1 - 0.19 11.2 0.9 0.28 10.6 0.6 1.2 1 0 0 1 1 1 0 Crinivirus P26 protein Peptidase_S8 PF00082.17 KEP65651.1 - 5.4e-31 107.7 0.8 8.1e-31 107.2 0.5 1.2 1 0 0 1 1 1 1 Subtilase family Ribosomal_S4 PF00163.14 KEP65652.1 - 8.4e-25 86.9 2.9 1.5e-24 86.1 2.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KEP65652.1 - 5.6e-13 48.1 0.8 5.6e-13 48.1 0.5 2.0 2 0 0 2 2 2 1 S4 domain HTH_31 PF13560.1 KEP65653.1 - 0.00078 19.5 0.1 0.0021 18.1 0.1 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain Nup54 PF13874.1 KEP65654.1 - 9.5e-27 93.3 1.6 9.5e-27 93.3 1.1 2.8 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KEP65654.1 - 9e-05 22.6 12.7 0.00021 21.5 8.8 1.6 1 0 0 1 1 1 1 Nucleoporin FG repeat region Cluap1 PF10234.4 KEP65654.1 - 0.075 12.2 2.7 1 8.4 0.2 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 Jnk-SapK_ap_N PF09744.4 KEP65654.1 - 0.16 11.9 0.2 0.16 11.9 0.1 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Calpain_inhib PF00748.14 KEP65654.1 - 0.18 12.1 3.1 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Calpain inhibitor Spc7 PF08317.6 KEP65654.1 - 0.25 9.9 4.5 1.1 7.8 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein EAP30 PF04157.11 KEP65654.1 - 0.85 8.7 12.4 0.33 10.0 0.3 2.7 3 0 0 3 3 3 0 EAP30/Vps36 family BLOC1_2 PF10046.4 KEP65654.1 - 1.1 9.4 7.8 7.8 6.6 0.5 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 KEP65654.1 - 3.8 7.4 9.1 2.6 8.0 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Chorein_N PF12624.2 KEP65655.1 - 0.0034 16.9 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 KEP65655.1 - 0.018 14.2 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1162) PI3_PI4_kinase PF00454.22 KEP65657.1 - 4.5e-40 137.5 0.0 1.1e-39 136.3 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KEP65657.1 - 6.7e-09 35.0 0.3 1.3e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 FATC domain XhoI PF04555.8 KEP65659.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease XhoI EXS PF03124.9 KEP65661.1 - 2.3e-69 234.0 8.5 3e-69 233.6 5.9 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KEP65661.1 - 5.2e-26 92.0 0.3 1.2e-13 51.4 0.0 2.2 2 0 0 2 2 2 2 SPX domain Ashwin PF15323.1 KEP65661.1 - 0.22 11.5 5.6 0.36 10.8 3.9 1.2 1 0 0 1 1 1 0 Developmental protein Pol_alpha_B_N PF08418.5 KEP65661.1 - 0.22 11.0 3.4 0.42 10.1 2.3 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 KEP65661.1 - 0.34 10.2 4.9 0.58 9.4 3.4 1.3 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 KEP65661.1 - 0.76 7.9 6.3 1.2 7.3 4.4 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF2638 PF10937.3 KEP65661.1 - 1.4 9.9 8.0 3.2 8.7 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) EF-hand_7 PF13499.1 KEP65663.1 - 0.014 15.5 0.6 0.32 11.1 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 KEP65663.1 - 0.027 13.7 0.1 0.079 12.3 0.1 1.8 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KEP65663.1 - 0.14 12.1 0.1 0.53 10.3 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain Aminotran_1_2 PF00155.16 KEP65664.1 - 3.4e-86 289.4 0.0 3.9e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Consortin_C PF15281.1 KEP65664.1 - 0.012 15.0 0.1 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Consortin C-terminus Actin PF00022.14 KEP65666.1 - 1.5e-131 438.4 0.0 1.8e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 Actin RCC1 PF00415.13 KEP65667.1 - 5.9e-114 372.1 58.7 3.4e-15 55.9 1.6 16.0 15 1 0 15 15 15 13 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP65667.1 - 1.2e-62 206.3 85.9 3.2e-08 32.9 0.6 14.4 14 0 0 14 14 14 13 Regulator of chromosome condensation (RCC1) repeat COX14 PF14880.1 KEP65668.1 - 7.8e-14 51.0 0.6 9.7e-14 50.7 0.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly PqqD PF05402.7 KEP65668.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Apc5 PF12862.2 KEP65668.1 - 0.073 12.9 0.1 0.099 12.4 0.0 1.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 Ndc1_Nup PF09531.5 KEP65668.1 - 0.1 10.9 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DivIC PF04977.10 KEP65668.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator H_PPase PF03030.11 KEP65669.1 - 5.8e-240 798.1 31.8 6.9e-240 797.9 22.1 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase GNVR PF13807.1 KEP65669.1 - 0.11 12.3 2.5 0.75 9.5 0.0 3.5 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase DUF4234 PF14018.1 KEP65670.1 - 4.6 7.0 6.1 69 3.2 4.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) zf-CCHC_3 PF13917.1 KEP65671.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle UCH PF00443.24 KEP65675.1 - 3.4e-10 39.4 0.0 5.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP65675.1 - 0.004 16.6 0.2 8.7 5.6 0.0 3.1 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase CPW_WPC PF09717.5 KEP65677.1 - 0.033 14.7 25.4 3.1 8.4 0.3 8.9 6 3 4 10 10 10 0 Plasmodium falciparum domain of unknown function (CPW_WPC) cEGF PF12662.2 KEP65677.1 - 0.13 11.8 0.0 0.13 11.8 0.0 9.7 12 0 0 12 12 12 0 Complement Clr-like EGF-like DIM PF08194.7 KEP65677.1 - 0.28 11.1 3.9 1.5 8.8 0.0 3.3 3 0 0 3 3 3 0 DIM protein EB PF01683.13 KEP65677.1 - 1.5 8.9 33.7 5.7 7.0 2.5 8.7 5 5 2 7 7 7 0 EB module Calcyon PF06387.6 KEP65677.1 - 4.5 6.5 16.9 1.1 8.5 0.1 5.0 6 0 0 6 6 6 0 D1 dopamine receptor-interacting protein (calcyon) HC2 PF07382.6 KEP65678.1 - 0.00055 19.8 64.4 0.00055 19.8 44.6 6.9 2 1 5 7 7 7 1 Histone H1-like nucleoprotein HC2 WG_beta_rep PF14903.1 KEP65678.1 - 0.00083 19.5 15.3 93 3.5 0.0 8.0 7 1 0 8 8 8 0 WG containing repeat EIID-AGA PF03613.9 KEP65679.1 - 0.0066 15.4 0.7 0.012 14.5 0.5 1.4 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component Cadherin-like PF12733.2 KEP65679.1 - 0.044 14.0 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Peptidase_S8 PF00082.17 KEP65680.1 - 4.2e-53 180.3 4.4 8.2e-53 179.3 3.0 1.4 1 0 0 1 1 1 1 Subtilase family DUF3353 PF11833.3 KEP65681.1 - 0.31 10.4 5.4 0.88 9.0 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) SRR1 PF07985.7 KEP65682.1 - 3.6e-12 46.0 0.1 7.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SRR1 Ribosomal_S21 PF01165.15 KEP65683.1 - 0.26 10.7 0.1 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S21 PI-PLC-X PF00388.14 KEP65688.1 - 1.3e-50 170.5 0.0 2.1e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEP65688.1 - 5.7e-29 100.4 0.0 1e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Mcp5_PH PF12814.2 KEP65688.1 - 2.9e-22 78.8 0.0 5.2e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology C2 PF00168.25 KEP65688.1 - 5.9e-09 35.6 0.0 1.4e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_10 PF14788.1 KEP65688.1 - 3e-06 26.7 0.1 6.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 KEP65688.1 - 9.2e-06 24.6 0.0 0.0008 18.5 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KEP65688.1 - 0.00013 21.5 0.2 0.0072 16.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KEP65688.1 - 0.00028 20.9 2.8 0.0036 17.3 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_like PF09279.6 KEP65688.1 - 0.0016 18.4 0.1 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 KEP65688.1 - 0.0031 17.1 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair MFS_1 PF07690.11 KEP65689.1 - 7.3e-24 84.1 37.3 7.3e-24 84.1 25.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M24 PF00557.19 KEP65690.1 - 1.8e-42 145.2 0.0 2.4e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-FCS PF06467.9 KEP65690.1 - 0.00022 20.8 3.3 0.00022 20.8 2.3 2.1 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif zf-MYND PF01753.13 KEP65690.1 - 0.00077 19.2 6.6 0.0028 17.5 4.6 2.0 1 0 0 1 1 1 1 MYND finger zinc-ribbons_6 PF07191.7 KEP65690.1 - 0.11 12.3 3.0 0.33 10.7 2.1 1.8 1 1 0 1 1 1 0 zinc-ribbons Nucleoplasmin PF03066.10 KEP65692.1 - 2.4 7.6 11.4 2.6 7.5 7.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin SNARE_assoc PF09335.6 KEP65693.1 - 6.8e-20 71.4 14.7 3.2e-19 69.3 6.2 3.0 3 0 0 3 3 3 2 SNARE associated Golgi protein Ras PF00071.17 KEP65694.1 - 1.2e-58 197.0 0.1 1.4e-58 196.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP65694.1 - 1.5e-20 73.8 0.2 3e-20 72.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEP65694.1 - 1.4e-12 47.2 0.0 1.7e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEP65694.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP65694.1 - 2.3e-07 30.4 0.0 5.8e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEP65694.1 - 3.3e-07 29.6 0.1 4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KEP65694.1 - 0.00048 20.2 0.0 0.00079 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEP65694.1 - 0.00088 18.4 0.4 0.002 17.3 0.1 1.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KEP65694.1 - 0.001 18.8 0.4 0.0087 15.7 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 KEP65694.1 - 0.001 19.1 0.1 0.028 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 KEP65694.1 - 0.001 18.3 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KEP65694.1 - 0.0026 17.3 0.2 0.1 12.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.13 KEP65694.1 - 0.004 16.2 0.1 0.0079 15.2 0.0 1.5 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 KEP65694.1 - 0.0042 16.6 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEP65694.1 - 0.0053 16.2 0.0 0.0082 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain MobB PF03205.9 KEP65694.1 - 0.0068 16.1 0.1 0.011 15.4 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KEP65694.1 - 0.013 14.9 0.1 0.041 13.3 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KEP65694.1 - 0.021 14.3 0.1 0.074 12.5 0.0 1.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KEP65694.1 - 0.024 14.3 0.0 0.071 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KEP65694.1 - 0.033 14.3 0.1 0.13 12.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase FeoB_N PF02421.13 KEP65694.1 - 0.035 13.3 0.2 0.55 9.4 0.2 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 KEP65694.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KEP65694.1 - 0.056 13.6 0.1 0.28 11.3 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KEP65694.1 - 0.058 13.0 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 KEP65694.1 - 0.11 12.3 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KEP65694.1 - 0.12 12.7 0.1 0.29 11.4 0.0 1.6 2 0 0 2 2 2 0 ABC transporter Actin PF00022.14 KEP65695.1 - 2.6e-52 177.5 0.0 3.7e-44 150.7 0.0 2.9 2 1 0 2 2 2 2 Actin zf-CCHC_3 PF13917.1 KEP65697.1 - 1.6e-19 69.3 3.9 5.8e-19 67.5 2.7 2.0 1 0 0 1 1 1 1 Zinc knuckle RAP1 PF07218.6 KEP65697.1 - 6.9 4.6 25.7 15 3.5 17.8 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mito_carr PF00153.22 KEP65698.1 - 2.3e-57 190.7 2.6 1.5e-18 66.3 0.0 4.7 4 1 0 4 4 4 4 Mitochondrial carrier protein Methyltransf_11 PF08241.7 KEP65699.1 - 1e-10 41.9 0.1 8e-09 35.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP65699.1 - 2.2e-06 27.5 0.0 8.3e-06 25.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP65699.1 - 5.5e-06 26.9 0.1 0.0018 18.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP65699.1 - 1.7e-05 25.0 0.4 0.00012 22.3 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP65699.1 - 9.4e-05 22.8 0.0 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP65699.1 - 0.0002 21.3 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP65699.1 - 0.0024 17.4 0.0 0.56 9.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain LRR_4 PF12799.2 KEP65700.1 - 1e-17 63.3 18.7 1.6e-05 24.4 0.6 5.1 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP65700.1 - 5.2e-15 54.9 6.1 1.5e-06 27.8 1.0 3.9 2 2 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KEP65700.1 - 3.2e-09 36.5 1.2 0.0017 17.9 1.6 2.7 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 KEP65700.1 - 0.034 14.1 14.8 4.1 7.8 0.2 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 KEP65700.1 - 0.13 12.5 8.2 28 5.5 0.1 5.7 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KEP65700.1 - 0.22 11.7 10.9 3.2 8.0 0.2 5.0 4 2 2 6 6 6 0 Leucine Rich repeat Nudc_N PF14050.1 KEP65701.1 - 1.4e-21 76.1 0.1 2.6e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 KEP65701.1 - 1.3e-09 38.4 0.1 2.1e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 CS domain Prenylcys_lyase PF07156.9 KEP65702.1 - 6.8e-11 41.6 0.0 0.0043 16.0 0.0 3.4 3 1 0 3 3 3 3 Prenylcysteine lyase NAD_binding_8 PF13450.1 KEP65702.1 - 0.053 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RCC1 PF00415.13 KEP65703.1 - 4.9e-66 218.7 33.4 3e-14 52.9 0.0 10.3 9 2 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP65703.1 - 2.1e-35 119.5 55.0 3.8e-11 42.2 0.9 8.9 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.6 KEP65703.1 - 0.025 13.8 0.2 46 3.1 0.0 4.1 5 0 0 5 5 5 0 TUP1-like enhancer of split CBM_X PF06204.6 KEP65703.1 - 0.087 12.3 4.6 6.7 6.2 0.0 3.8 4 0 0 4 4 4 0 Putative carbohydrate binding domain Nucleoporin_N PF08801.6 KEP65703.1 - 0.13 10.9 0.0 4.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like Methyltransf_18 PF12847.2 KEP65704.1 - 2.8e-11 43.9 0.0 6.4e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP65704.1 - 1.9e-08 34.0 0.0 1.8e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP65704.1 - 1.2e-06 28.5 1.2 5.4e-06 26.4 0.8 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEP65704.1 - 3.2e-05 24.3 0.0 7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP65704.1 - 4.4e-05 23.7 0.0 0.00013 22.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP65704.1 - 4.5e-05 23.8 0.0 0.00014 22.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP65704.1 - 7.4e-05 22.5 0.0 0.00046 19.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEP65704.1 - 9.4e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KEP65704.1 - 0.0028 16.4 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 KEP65704.1 - 0.0032 16.6 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 KEP65704.1 - 0.043 13.4 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pox_MCEL PF03291.11 KEP65704.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme MetW PF07021.7 KEP65704.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spond_N PF06468.8 KEP65705.1 - 0.089 12.4 0.3 0.13 11.9 0.2 1.3 1 1 0 1 1 1 0 Spondin_N MRP-S31 PF15433.1 KEP65705.1 - 0.11 11.8 5.2 0.15 11.4 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Kinesin PF00225.18 KEP65706.1 - 1.8e-92 309.6 0.0 2.9e-92 308.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain IncA PF04156.9 KEP65706.1 - 5 6.6 15.3 0.12 12.0 5.7 1.7 2 0 0 2 2 2 0 IncA protein Exo_endo_phos PF03372.18 KEP65707.1 - 8.3e-13 48.8 0.0 2.4e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PAN_4 PF14295.1 KEP65708.1 - 4.2e-23 80.8 17.7 2.5e-07 30.2 1.8 4.6 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.21 KEP65708.1 - 2.5e-18 65.5 28.1 3e-05 23.6 0.0 5.1 4 1 1 5 5 5 4 PAN domain UAA PF08449.6 KEP65709.1 - 2.5e-13 49.6 0.7 2.6e-11 43.0 0.0 2.5 3 0 0 3 3 3 1 UAA transporter family EamA PF00892.15 KEP65709.1 - 0.058 13.4 13.8 0.086 12.8 0.0 3.6 4 0 0 4 4 4 0 EamA-like transporter family TPT PF03151.11 KEP65709.1 - 0.12 12.0 9.8 6.2 6.4 4.8 3.9 3 1 0 3 3 3 0 Triose-phosphate Transporter family Ras PF00071.17 KEP65710.1 - 2e-53 180.0 0.2 2.8e-53 179.6 0.1 1.2 1 0 0 1 1 1 1 Ras family Kelch_4 PF13418.1 KEP65710.1 - 1.2e-31 108.1 0.3 3.5e-09 36.2 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP65710.1 - 6.7e-27 92.9 1.2 4.4e-05 23.5 0.0 8.7 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KEP65710.1 - 6.3e-21 73.9 3.0 1.5e-05 24.8 0.0 7.1 6 2 0 6 6 6 4 Kelch motif Miro PF08477.8 KEP65710.1 - 2.5e-16 60.2 0.0 6.1e-16 58.9 0.0 1.7 2 0 0 2 2 1 1 Miro-like protein Kelch_6 PF13964.1 KEP65710.1 - 8.8e-16 57.3 0.0 2.4e-05 24.3 0.0 5.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KEP65710.1 - 4.1e-13 48.5 0.0 0.0098 15.6 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Arf PF00025.16 KEP65710.1 - 9.9e-13 47.6 0.0 1.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Kelch_1 PF01344.20 KEP65710.1 - 8.2e-08 31.6 0.0 0.1 12.1 0.0 5.4 5 0 0 5 5 5 1 Kelch motif Gtr1_RagA PF04670.7 KEP65710.1 - 1.5e-07 30.7 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEP65710.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP65710.1 - 0.0054 16.1 0.0 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEP65710.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Thymidylat_synt PF00303.14 KEP65711.1 - 1.1e-115 385.3 0.0 1.4e-115 384.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 KEP65711.1 - 3.3e-27 95.0 0.0 5.5e-20 71.5 0.0 2.3 2 0 0 2 2 2 2 Dihydrofolate reductase AP2 PF00847.15 KEP65712.1 - 0.0012 18.9 0.1 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 AP2 domain TraV PF09676.5 KEP65712.1 - 0.13 12.9 2.3 4.6 7.9 0.5 2.5 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Ctr PF04145.10 KEP65713.1 - 2.1e-21 76.5 11.9 7.4e-20 71.4 8.2 2.2 1 1 0 1 1 1 1 Ctr copper transporter family DUF2534 PF10749.4 KEP65713.1 - 7 6.6 7.0 12 5.8 1.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) TPR_10 PF13374.1 KEP65715.1 - 0.088 12.7 0.4 0.28 11.1 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-hand_1 PF00036.27 KEP65716.1 - 1.1e-41 136.9 12.3 2.5e-10 38.8 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP65716.1 - 8.6e-37 125.1 6.3 3.3e-20 71.9 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEP65716.1 - 1.3e-32 111.1 11.2 3e-16 58.7 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KEP65716.1 - 9e-31 102.9 6.4 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEP65716.1 - 1.9e-28 96.4 8.0 8.3e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KEP65716.1 - 3.3e-15 55.7 0.1 3.5e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEP65716.1 - 1.2e-09 37.7 0.4 0.00022 20.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEP65716.1 - 1.3e-08 34.8 0.0 0.0014 18.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 KEP65716.1 - 4.7e-06 26.4 1.3 6.2e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 KEP65716.1 - 7.4e-06 25.4 0.1 0.19 11.3 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 KEP65716.1 - 0.00031 20.4 0.3 0.15 11.7 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KEP65716.1 - 0.00048 19.7 0.2 0.037 13.5 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein DUF1103 PF06513.6 KEP65716.1 - 0.0037 16.6 1.5 0.0043 16.4 1.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) RNA_pol_Rpb4 PF03874.11 KEP65716.1 - 0.0059 16.5 0.4 1.7 8.6 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 YqeY PF09424.5 KEP65716.1 - 0.0097 15.7 0.3 0.11 12.3 0.1 2.0 1 1 1 2 2 2 1 Yqey-like protein EF-hand_like PF09279.6 KEP65716.1 - 0.012 15.6 0.8 0.15 12.0 0.1 2.5 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like MotA_activ PF09114.5 KEP65716.1 - 0.03 14.0 0.2 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Tenui_NCP PF04876.7 KEP65716.1 - 0.031 13.8 0.1 0.37 10.3 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF853 PF05872.7 KEP65716.1 - 0.059 11.7 0.1 1.6 6.9 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) LNS2 PF08235.8 KEP65716.1 - 0.061 12.8 0.0 0.44 10.0 0.0 1.9 1 1 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF1880 PF08976.6 KEP65716.1 - 0.083 13.0 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) SpoVIF PF14069.1 KEP65716.1 - 0.1 12.3 0.4 1.6 8.4 0.1 2.4 2 1 0 2 2 2 0 Stage VI sporulation protein F Toprim_2 PF13155.1 KEP65716.1 - 0.11 12.8 0.7 13 6.2 0.0 2.6 1 1 1 2 2 2 0 Toprim-like VCBS PF13517.1 KEP65716.1 - 7.5 7.0 6.5 30 5.0 0.4 2.6 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_L35Ae PF01247.13 KEP65717.1 - 1.4e-41 140.1 0.4 1.6e-41 139.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KEP65717.1 - 0.005 16.7 0.0 3.4 7.6 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.20 KEP65718.1 - 8.4e-51 172.6 0.0 3.5e-24 85.3 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65718.1 - 2.3e-16 59.6 0.1 5e-13 48.7 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP65718.1 - 0.034 13.1 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 KEP65718.1 - 0.21 11.1 0.1 7.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 KEP65718.1 - 0.45 9.3 0.0 0.65 8.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Thioredoxin PF00085.15 KEP65719.1 - 2e-54 181.6 0.0 5.2e-31 106.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 KEP65719.1 - 5.6e-12 45.6 0.0 1.4e-05 25.0 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KEP65719.1 - 1.1e-11 44.5 0.2 0.0002 21.3 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 KEP65719.1 - 3.8e-11 43.1 0.0 6e-06 26.1 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KEP65719.1 - 1.1e-10 41.6 1.3 0.00013 22.0 0.1 4.4 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KEP65719.1 - 2.7e-07 30.2 0.0 0.029 14.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.16 KEP65719.1 - 1.1e-05 25.0 0.1 0.0093 15.6 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.1 KEP65719.1 - 6e-05 22.6 0.1 0.16 11.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 KEP65719.1 - 0.00058 19.4 0.2 0.18 11.3 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 KEP65719.1 - 0.0016 18.4 0.1 1.3 9.0 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin DUF826 PF05696.6 KEP65719.1 - 0.084 13.0 0.1 0.78 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF826) DDE_Tnp_1_2 PF13586.1 KEP65719.1 - 0.1 12.8 0.0 4 7.6 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain DUF2948 PF11164.3 KEP65720.1 - 0.0097 15.5 0.2 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2948) PIH1 PF08190.7 KEP65721.1 - 3e-37 128.8 0.1 3e-37 128.8 0.1 2.5 2 1 0 2 2 2 1 pre-RNA processing PIH1/Nop17 Abhydrolase_5 PF12695.2 KEP65722.1 - 0.00045 19.9 0.1 0.0026 17.4 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEP65722.1 - 0.0028 16.8 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 KEP65722.1 - 0.11 11.8 0.0 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) CopD PF05425.8 KEP65722.1 - 4.3 7.5 10.9 8.3 6.6 7.6 1.4 1 0 0 1 1 1 0 Copper resistance protein D UPF0172 PF03665.8 KEP65723.1 - 3.4e-31 108.2 0.1 8.3e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0172) JAB PF01398.16 KEP65723.1 - 0.11 12.1 0.0 0.47 10.2 0.0 2.0 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease X PF00739.14 KEP65723.1 - 2.7 7.9 7.2 8 6.3 5.0 1.8 1 0 0 1 1 1 0 Trans-activation protein X Flavodoxin_1 PF00258.20 KEP65724.1 - 6.9e-21 74.7 0.4 1.5e-18 67.1 0.1 2.5 2 0 0 2 2 2 2 Flavodoxin NAD_binding_1 PF00175.16 KEP65724.1 - 5.7e-08 33.3 0.0 3.7e-07 30.7 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 KEP65724.1 - 4e-06 26.4 10.2 0.0004 19.8 0.0 3.5 4 0 0 4 4 4 2 FAD binding domain Apt1 PF10351.4 KEP65724.1 - 0.59 8.9 3.5 0.79 8.5 0.8 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2207 PF09972.4 KEP65726.1 - 0.35 9.4 1.1 0.41 9.1 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_5 PF12695.2 KEP65728.1 - 7.2e-17 61.4 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP65728.1 - 9e-10 38.8 0.0 3.2e-07 30.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEP65728.1 - 8.5e-07 28.6 0.0 4.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 KEP65728.1 - 0.00081 19.0 0.1 0.021 14.3 0.0 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KEP65728.1 - 0.0026 17.3 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEP65728.1 - 0.0065 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KEP65728.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 KEP65728.1 - 0.076 11.8 0.0 0.49 9.2 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme DDHD PF02862.12 KEP65728.1 - 5.8 6.6 11.6 6.5 6.4 0.2 2.1 2 0 0 2 2 2 0 DDHD domain Hph PF13694.1 KEP65728.1 - 6.2 6.7 11.9 0.088 12.8 2.1 1.9 2 0 0 2 2 2 0 Sec63/Sec62 complex-interacting family RED_N PF07808.8 KEP65729.1 - 7.3e-30 103.9 11.6 7.3e-30 103.9 8.0 3.0 3 1 0 3 3 3 1 RED-like protein N-terminal region RED_C PF07807.6 KEP65729.1 - 6.9e-14 52.0 3.0 6.9e-14 52.0 2.1 3.0 3 0 0 3 3 3 1 RED-like protein C-terminal region IFT46_B_C PF12317.3 KEP65730.1 - 1e-24 87.1 0.0 1.2e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Creatinase_N PF01321.13 KEP65730.1 - 0.13 12.7 0.0 0.44 11.0 0.0 1.7 1 1 1 2 2 2 0 Creatinase/Prolidase N-terminal domain SUI1 PF01253.17 KEP65731.1 - 2e-27 94.8 0.6 2.8e-27 94.3 0.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 zf-DHHC PF01529.15 KEP65732.1 - 9.6e-27 93.4 2.3 9.6e-27 93.4 1.6 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase ELFV_dehydrog PF00208.16 KEP65733.1 - 4.9e-47 160.5 0.0 8.5e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KEP65733.1 - 6.3e-26 90.2 0.0 2e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase KCNQC3-Ank-G_bd PF11956.3 KEP65733.1 - 0.054 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 HAUS-augmin3 PF14932.1 KEP65736.1 - 0.049 12.8 0.9 0.066 12.3 0.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Alpha-E PF04168.7 KEP65737.1 - 0.1 11.9 7.5 0.42 9.9 0.5 2.8 2 1 1 3 3 3 0 A predicted alpha-helical domain with a conserved ER motif. WD40 PF00400.27 KEP65739.1 - 2e-25 87.6 16.3 1.8e-06 27.5 0.0 7.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Pkinase PF00069.20 KEP65740.1 - 3e-07 29.8 0.0 2.5e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KEP65740.1 - 0.0057 15.6 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TPR_1 PF00515.23 KEP65741.1 - 1.9e-18 65.2 4.3 4e-06 26.1 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEP65741.1 - 2.1e-16 59.3 8.0 3.7e-10 39.2 1.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KEP65741.1 - 1.3e-13 49.7 8.5 0.00068 19.3 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEP65741.1 - 1.2e-05 24.7 0.7 4.9 7.1 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEP65741.1 - 2.2e-05 24.1 5.2 0.0065 16.2 1.6 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEP65741.1 - 8.6e-05 22.4 0.3 0.018 15.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEP65741.1 - 0.00018 21.3 8.6 0.0034 17.2 1.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEP65741.1 - 0.00036 20.7 2.1 21 5.8 0.0 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEP65741.1 - 0.0014 18.6 2.4 0.16 12.0 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP65741.1 - 0.027 14.2 2.9 2.5 8.0 0.0 3.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEP65741.1 - 0.043 14.4 0.3 0.043 14.4 0.2 6.6 7 2 1 8 8 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP65741.1 - 0.15 12.7 0.1 0.15 12.7 0.1 7.3 7 1 1 8 8 5 0 Tetratricopeptide repeat Arm PF00514.18 KEP65741.1 - 0.92 9.4 13.9 0.46 10.3 0.4 5.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat PA26 PF04636.8 KEP65744.1 - 1 7.9 8.7 1.5 7.4 6.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HSP70 PF00012.15 KEP65744.1 - 1.4 6.7 9.3 1.5 6.6 6.4 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4407 PF14362.1 KEP65744.1 - 1.4 7.7 6.4 1.5 7.6 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 KEP65744.1 - 2.3 5.9 6.9 2.6 5.7 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4398 PF14346.1 KEP65744.1 - 2.6 8.1 16.5 4.3 7.4 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) IncA PF04156.9 KEP65744.1 - 2.9 7.4 9.5 3.8 7.0 6.6 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KEP65744.1 - 3.4 6.6 11.5 4.4 6.2 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 KEP65744.1 - 3.7 5.7 12.7 3.9 5.6 8.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein BTV_NS2 PF04514.7 KEP65744.1 - 4.5 6.0 15.3 6.1 5.6 10.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 OmpH PF03938.9 KEP65744.1 - 5.9 6.8 12.7 9.1 6.1 8.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ycf1 PF05758.7 KEP65744.1 - 7.9 4.0 9.2 8.3 3.9 6.4 1.1 1 0 0 1 1 1 0 Ycf1 CRM1_C PF08767.6 KEP65745.1 - 2e-109 365.4 6.0 2e-109 365.4 4.2 3.1 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 KEP65745.1 - 7.8e-39 132.9 9.1 1.9e-38 131.6 3.8 3.6 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KEP65745.1 - 4.6e-10 39.2 0.1 2.3e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3945 PF13101.1 KEP65745.1 - 0.075 12.3 0.1 16 4.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) DZR PF12773.2 KEP65747.1 - 0.35 10.7 23.5 0.047 13.5 5.1 4.0 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 KEP65747.1 - 3 7.4 12.7 3.1 7.3 0.6 3.8 3 0 0 3 3 3 0 zinc-ribbon domain RNA_pol_L PF01193.19 KEP65748.1 - 1.2e-10 40.3 0.0 2.7e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.21 KEP65748.1 - 1.4e-05 25.1 0.0 0.0042 17.2 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb3/RpoA insert domain HTH_17 PF12728.2 KEP65748.1 - 0.25 11.6 1.9 1.8 8.8 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain C2 PF00168.25 KEP65749.1 - 2.9e-08 33.4 0.2 3.1e-06 26.9 0.1 2.6 1 1 0 1 1 1 1 C2 domain Transglut_core PF01841.14 KEP65749.1 - 0.037 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF553 PF04473.7 KEP65749.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain AAA_18 PF13238.1 KEP65751.1 - 0.0015 18.8 0.0 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEP65751.1 - 0.0021 18.8 0.0 0.0088 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KEP65751.1 - 0.011 15.3 0.0 3.1 7.2 0.0 2.2 1 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 KEP65751.1 - 0.021 14.6 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain UPF0506 PF11703.3 KEP65753.1 - 0.1 12.6 13.0 0.046 13.6 7.0 1.9 2 0 0 2 2 2 0 UPF0506 YlaC PF10777.4 KEP65754.1 - 0.11 11.9 0.2 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Inner membrane protein YlaC PseudoU_synth_2 PF00849.17 KEP65755.1 - 2.2e-21 76.3 0.0 4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase CAP160 PF07918.6 KEP65756.1 - 0.21 11.2 0.5 0.45 10.1 0.3 1.5 1 0 0 1 1 1 0 CAP160 repeat Cullin PF00888.17 KEP65757.1 - 3.7e-109 365.8 0.1 5.3e-109 365.3 0.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEP65757.1 - 3.5e-25 87.6 0.7 7.5e-25 86.5 0.5 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Fasciclin PF02469.17 KEP65759.1 - 2.5e-07 30.7 0.0 0.00057 19.8 0.2 4.1 4 0 0 4 4 4 1 Fasciclin domain zf-C3HC4 PF00097.20 KEP65759.1 - 0.15 11.7 0.6 0.3 10.7 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 KEP65760.1 - 2.6e-25 87.3 17.2 6.9e-06 25.7 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KEP65760.1 - 6.1e-05 22.8 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A FAST_1 PF06743.10 KEP65761.1 - 0.00031 20.4 10.3 5 6.9 0.0 6.6 6 0 0 6 6 6 4 FAST kinase-like protein, subdomain 1 DED PF01335.16 KEP65761.1 - 0.048 13.7 1.3 0.32 11.1 0.4 2.8 2 0 0 2 2 2 0 Death effector domain DUF2763 PF10961.3 KEP65762.1 - 7.7e-06 26.2 0.7 7.7e-06 26.2 0.5 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2763) PPR_2 PF13041.1 KEP65764.1 - 0.0091 15.9 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 KEP65764.1 - 0.049 13.9 0.3 1.4 9.4 0.0 2.7 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF2460 PF09343.5 KEP65767.1 - 0.079 12.2 0.1 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) MAD PF05557.8 KEP65768.1 - 1.8e-05 23.0 90.3 0.008 14.3 62.6 3.5 1 1 0 1 1 1 1 Mitotic checkpoint protein Rootletin PF15035.1 KEP65768.1 - 0.013 15.4 14.6 0.013 15.4 10.1 6.4 3 2 3 6 6 6 0 Ciliary rootlet component, centrosome cohesion AAA_13 PF13166.1 KEP65768.1 - 7.8 4.8 65.6 2.2 6.6 16.4 3.2 1 1 1 3 3 3 0 AAA domain CBM_48 PF02922.13 KEP65769.1 - 1.7e-21 76.0 0.1 1.2e-20 73.3 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.13 KEP65769.1 - 2.2e-19 69.3 0.0 9e-19 67.4 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KEP65769.1 - 2.5e-15 56.7 0.0 4.8e-08 32.7 0.0 2.9 1 1 1 2 2 2 2 Alpha amylase, catalytic domain zf-CCCH PF00642.19 KEP65770.1 - 0.01 15.4 0.3 0.024 14.3 0.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2040 PF09745.4 KEP65771.1 - 5.2e-18 65.0 13.6 3.3e-15 56.0 4.6 3.9 4 1 0 4 4 4 2 Coiled-coil domain-containing protein 55 (DUF2040) XRN_N PF03159.13 KEP65772.1 - 3.5e-47 160.7 11.4 5.8e-41 140.4 0.0 4.3 5 0 0 5 5 5 3 XRN 5'-3' exonuclease N-terminus Pacs-1 PF10254.4 KEP65773.1 - 1.3 7.5 0.9 3.2 6.3 0.6 1.5 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein TRAM_LAG1_CLN8 PF03798.11 KEP65774.1 - 1.4e-30 106.3 19.2 1.4e-30 106.3 13.3 1.6 2 0 0 2 2 2 1 TLC domain V_ATPase_I PF01496.14 KEP65774.1 - 0.084 10.7 0.0 0.11 10.3 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAT PF02259.18 KEP65775.1 - 1.5e-49 168.9 11.0 3.6e-22 78.8 0.2 4.6 4 0 0 4 4 4 4 FAT domain PI3_PI4_kinase PF00454.22 KEP65775.1 - 1.4e-44 152.3 0.0 2.4e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KEP65775.1 - 2.1e-25 88.7 0.2 7.4e-25 86.9 0.1 2.1 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 KEP65775.1 - 6.7e-13 47.8 0.1 1.7e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_7 PF13176.1 KEP65775.1 - 0.0012 18.4 7.2 0.012 15.3 0.3 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP65775.1 - 0.021 15.5 12.6 0.009 16.6 1.1 4.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP65775.1 - 0.03 14.2 1.0 9.5 6.4 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP65775.1 - 0.056 14.0 10.7 0.2 12.3 0.1 5.9 5 0 0 5 5 4 0 Tetratricopeptide repeat RR_TM4-6 PF06459.7 KEP65775.1 - 0.45 10.3 5.8 1 9.1 4.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TPR_11 PF13414.1 KEP65775.1 - 0.49 10.0 8.7 0.55 9.9 0.1 3.6 4 0 0 4 4 3 0 TPR repeat HEAT PF02985.17 KEP65775.1 - 0.77 10.0 17.7 0.98 9.6 0.4 5.9 5 1 0 5 5 4 0 HEAT repeat TPR_19 PF14559.1 KEP65775.1 - 1.3 9.4 7.1 3.4 8.0 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.2 KEP65776.1 - 1.1e-23 82.3 7.7 1.4e-06 27.7 0.2 4.3 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP65776.1 - 2.1e-16 59.3 5.5 8.2e-09 35.1 0.9 2.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KEP65776.1 - 3.7e-10 39.6 1.2 0.00041 19.9 0.0 2.2 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KEP65776.1 - 9.5e-08 31.3 5.9 0.19 11.8 0.2 5.7 5 1 1 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 KEP65776.1 - 3.4e-07 29.3 11.8 0.2 11.8 0.0 6.2 4 1 2 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 KEP65776.1 - 0.11 12.7 16.2 3.5 8.2 0.1 5.8 5 2 1 6 6 6 0 Leucine rich repeat Tet_JBP PF12851.2 KEP65777.1 - 0.074 12.3 0.3 0.15 11.3 0.1 1.6 1 1 1 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily LRR_8 PF13855.1 KEP65777.1 - 0.12 12.1 2.5 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 Leucine rich repeat Tubulin PF00091.20 KEP65778.1 - 3.4e-68 229.6 0.0 4.6e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEP65778.1 - 1.8e-51 173.4 0.3 7.6e-51 171.4 0.1 1.9 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KEP65778.1 - 0.027 13.9 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain Methyltransf_16 PF10294.4 KEP65781.1 - 9.4e-19 67.5 0.0 2.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Profilin PF00235.14 KEP65782.1 - 0.0014 18.7 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Profilin SURF6 PF04935.7 KEP65783.1 - 2.1e-07 30.4 57.3 2.1e-07 30.4 39.7 2.5 2 1 0 3 3 3 1 Surfeit locus protein 6 DUF4252 PF14060.1 KEP65783.1 - 4.1 6.9 12.2 4.8 6.7 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) Sod_Fe_C PF02777.13 KEP65785.1 - 1.5e-37 127.6 1.4 4e-37 126.2 0.6 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEP65785.1 - 4.6e-31 106.9 0.4 8.8e-31 106.0 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ABC_membrane PF00664.18 KEP65786.1 - 5.6e-27 94.8 6.2 7.4e-27 94.4 4.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KEP65786.1 - 1.7e-25 89.8 0.0 2.9e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 KEP65786.1 - 0.00062 19.4 0.2 0.91 9.1 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KEP65786.1 - 0.016 15.1 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KEP65786.1 - 0.018 14.6 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEP65786.1 - 0.019 15.7 0.0 0.04 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEP65786.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KEP65786.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEP65786.1 - 0.063 12.3 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.13 KEP65786.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 KEP65786.1 - 0.14 11.6 0.1 0.37 10.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Inhibitor_I71 PF12628.2 KEP65786.1 - 0.26 10.9 0.0 0.46 10.1 0.0 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DUF3584 PF12128.3 KEP65786.1 - 0.68 7.1 0.9 0.89 6.7 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Sod_Fe_C PF02777.13 KEP65787.1 - 1.2e-41 140.7 0.4 2.5e-40 136.5 0.2 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEP65787.1 - 1.2e-31 108.7 0.3 2.4e-31 107.8 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DEAD PF00270.24 KEP65788.1 - 6.7e-19 67.9 0.0 6.2e-18 64.8 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP65788.1 - 1.8e-18 66.1 0.0 4.7e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP65788.1 - 1.8e-05 24.6 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DivIC PF04977.10 KEP65788.1 - 0.047 13.1 1.3 0.12 11.8 0.9 1.6 1 0 0 1 1 1 0 Septum formation initiator DegS PF05384.6 KEP65789.1 - 0.0016 17.6 13.9 0.0026 16.9 9.7 1.2 1 0 0 1 1 1 1 Sensor protein DegS DUF3373 PF11853.3 KEP65789.1 - 0.043 12.3 6.1 0.056 11.9 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) CDK5_activator PF03261.10 KEP65789.1 - 0.25 10.6 7.5 0.33 10.2 5.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Mitovir_RNA_pol PF05919.6 KEP65789.1 - 0.29 10.0 5.2 0.38 9.6 3.6 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Fib_alpha PF08702.5 KEP65789.1 - 0.56 10.3 12.4 0.65 10.1 5.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FH2 PF02181.18 KEP65789.1 - 0.66 8.8 12.4 0.91 8.3 8.6 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain 5-FTHF_cyc-lig PF01812.15 KEP65789.1 - 4.8 6.9 9.5 5.7 6.6 5.8 1.6 1 1 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Ax_dynein_light PF10211.4 KEP65789.1 - 5.3 6.8 17.6 1.6 8.5 9.8 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain bZIP_2 PF07716.10 KEP65789.1 - 5.7 6.8 12.8 0.77 9.6 2.6 3.3 2 1 1 3 3 3 0 Basic region leucine zipper Penicil_amidase PF01804.13 KEP65789.1 - 6.1 5.7 9.2 7.7 5.4 6.3 1.0 1 0 0 1 1 1 0 Penicillin amidase DUF2408 PF10303.4 KEP65789.1 - 6.2 6.9 13.6 4.7 7.3 1.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) MFS_1 PF07690.11 KEP65790.1 - 1.9e-30 105.7 39.9 1.5e-22 79.8 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KEP65790.1 - 0.0093 14.4 21.4 0.077 11.4 5.6 2.7 2 2 0 2 2 2 2 Vacuole effluxer Atg22 like Prenyltrans PF00432.16 KEP65791.1 - 5.8e-48 160.1 20.1 4.6e-10 38.8 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEP65791.1 - 8.2e-30 103.5 0.5 3.3e-17 62.9 0.1 3.2 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEP65791.1 - 9e-10 38.5 0.0 0.0062 16.5 0.0 4.1 1 1 3 4 4 4 3 Prenyltransferase-like A2M_comp PF07678.9 KEP65791.1 - 2.4e-05 23.7 0.1 0.24 10.6 0.0 3.8 3 1 1 4 4 4 2 A-macroglobulin complement component Dynactin_p62 PF05502.8 KEP65795.1 - 2e-25 89.5 18.3 1.1e-14 54.1 12.3 3.2 2 1 0 2 2 2 2 Dynactin p62 family DUF3006 PF11213.3 KEP65796.1 - 0.0042 16.8 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) P33MONOX PF15302.1 KEP65796.1 - 0.33 10.5 2.5 0.42 10.1 1.8 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase Herpes_capsid PF06112.6 KEP65796.1 - 3.8 7.5 9.0 6 6.9 6.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Syja_N PF02383.13 KEP65797.1 - 1.2e-66 224.6 0.0 2.1e-66 223.8 0.0 1.4 1 1 0 1 1 1 1 SacI homology domain Med6 PF04934.9 KEP65798.1 - 8.2e-16 57.8 0.0 4.3e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 MED6 mediator sub complex component DUF2492 PF10678.4 KEP65798.1 - 0.031 14.3 0.2 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) His_Phos_1 PF00300.17 KEP65799.1 - 1.6e-07 31.5 0.0 7.5e-06 26.1 0.0 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) OmpA PF00691.15 KEP65799.1 - 0.049 14.0 0.1 4.7 7.6 0.1 2.6 2 0 0 2 2 2 0 OmpA family Sod_Fe_C PF02777.13 KEP65800.1 - 5.6e-38 129.0 1.0 5.6e-38 129.0 0.7 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEP65800.1 - 2e-31 108.0 3.5 2e-31 108.0 2.4 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Lip_prot_lig_C PF10437.4 KEP65800.1 - 0.16 11.6 0.4 0.35 10.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus FF PF01846.14 KEP65801.1 - 4.9e-26 90.4 6.7 4.2e-10 39.4 0.2 5.8 6 0 0 6 6 6 4 FF domain SR-25 PF10500.4 KEP65801.1 - 0.00015 21.2 13.0 0.00015 21.2 9.0 2.5 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein WW PF00397.21 KEP65801.1 - 0.00066 19.4 4.0 0.0017 18.1 2.8 1.7 1 0 0 1 1 1 1 WW domain RAP1 PF07218.6 KEP65801.1 - 0.1 10.6 5.9 0.16 10.0 4.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 KEP65802.1 - 6.5e-65 218.8 0.0 9.2e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65802.1 - 5.3e-41 140.3 0.0 8.1e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP65802.1 - 0.0019 17.9 0.5 0.23 11.1 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEP65802.1 - 0.053 12.5 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KEP65802.1 - 1.4 7.6 0.0 2.1 7.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Romo1 PF10247.4 KEP65803.1 - 7.5e-21 74.0 10.5 1e-20 73.6 7.3 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_OmpA PF13436.1 KEP65803.1 - 0.2 11.3 0.9 0.35 10.5 0.6 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain MMR_HSR1 PF01926.18 KEP65805.1 - 8.8e-17 61.1 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 KEP65805.1 - 3.3e-13 49.5 10.0 1.1e-05 25.0 1.2 3.9 4 0 0 4 4 4 3 GTP1/OBG FeoB_N PF02421.13 KEP65805.1 - 2.4e-08 33.4 0.0 2.3e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEP65805.1 - 2.2 8.0 8.4 3.7e+02 0.8 5.8 3.3 1 1 0 1 1 1 0 Dynamin family Ribosomal_S15 PF00312.17 KEP65806.1 - 5.1e-16 58.2 0.9 1.4e-15 56.8 0.6 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 Spore_coat_CotO PF14153.1 KEP65806.1 - 0.039 13.3 16.3 0.067 12.6 11.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO MIP-T3 PF10243.4 KEP65806.1 - 0.11 10.9 27.3 0.2 10.1 18.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 KEP65806.1 - 1.2 8.9 26.5 0.27 11.1 16.0 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 KEP65806.1 - 1.4 6.5 17.2 1.9 6.0 11.9 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 KEP65806.1 - 3.2 7.0 25.5 5.4 6.3 17.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 KEP65806.1 - 7.2 6.5 22.3 15 5.5 15.5 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TGT PF01702.13 KEP65807.1 - 6.1e-84 281.0 0.0 9.7e-84 280.3 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF1510 PF07423.6 KEP65807.1 - 3.1 7.0 12.1 4.1 6.7 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RNA_pol_Rpc4 PF05132.9 KEP65807.1 - 4.4 7.3 10.5 1.2 9.1 2.8 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Rpr2 PF04032.11 KEP65808.1 - 0.00016 21.4 0.0 0.00039 20.2 0.0 1.7 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain FdhE PF04216.7 KEP65808.1 - 0.093 12.4 1.2 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Peptidase_C97 PF05903.9 KEP65809.1 - 6.9e-24 84.3 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KEP65809.1 - 0.0093 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Radical_SAM PF04055.16 KEP65811.1 - 2.6e-23 83.0 0.0 4.4e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 KEP65811.1 - 8.9e-10 38.5 0.0 2.9e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Wyosine base formation zf-RING_2 PF13639.1 KEP65812.1 - 5.4e-15 54.9 6.8 1.6e-14 53.3 4.7 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEP65812.1 - 8.6e-08 31.7 6.0 8.6e-08 31.7 4.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 KEP65812.1 - 6.1e-07 29.4 3.1 1.6e-06 28.1 2.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP65812.1 - 1.5e-06 27.7 4.6 1.5e-06 27.7 3.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP65812.1 - 3.9e-06 26.7 6.6 3.9e-06 26.7 4.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP65812.1 - 0.00015 21.3 4.2 0.00015 21.3 2.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEP65812.1 - 0.004 16.8 1.1 0.0075 15.9 0.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KEP65812.1 - 0.084 12.7 2.2 0.2 11.4 1.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KEP65812.1 - 1.1 9.4 5.3 2.4 8.2 3.6 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KEP65812.1 - 1.3 9.0 4.5 4.9 7.1 3.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KEP65812.1 - 2.2 8.0 6.1 5 6.8 4.2 1.7 1 0 0 1 1 1 0 PHD-finger zf-P11 PF03854.9 KEP65812.1 - 6.7 6.2 9.4 0.34 10.4 2.5 2.0 2 1 0 2 2 2 0 P-11 zinc finger LMF1 PF06762.9 KEP65813.1 - 1.8e-121 405.5 4.3 3e-119 398.2 0.5 2.9 2 1 0 2 2 2 2 Lipase maturation factor DUF4345 PF14248.1 KEP65814.1 - 0.017 14.5 0.1 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) DUF961 PF06125.6 KEP65814.1 - 0.058 13.5 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) RNA_pol_L_2 PF13656.1 KEP65815.1 - 6.1e-18 64.0 0.0 8.7e-18 63.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KEP65815.1 - 5e-05 22.3 0.0 7.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GlcNAc PF11397.3 KEP65818.1 - 2.7e-39 135.2 3.6 9.6e-23 80.8 0.0 5.5 4 2 0 4 4 4 3 Glycosyltransferase (GlcNAc) DPCD PF14913.1 KEP65818.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 DPCD protein family DUF3638 PF12340.3 KEP65819.1 - 5.2e-17 61.5 0.0 1.2e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KEP65819.1 - 1.3e-15 56.2 0.2 3.2e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.1 KEP65819.1 - 1.7e-07 31.2 0.1 0.00018 21.5 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP65819.1 - 4.5e-06 26.1 0.2 0.46 10.4 0.0 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KEP65819.1 - 0.00032 20.2 0.2 0.0083 15.7 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KEP65819.1 - 0.0012 17.9 0.0 0.033 13.5 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KEP65819.1 - 0.71 9.3 3.5 0.24 10.8 0.1 2.1 2 0 0 2 2 2 0 EF hand ResIII PF04851.10 KEP65819.1 - 1.1 9.1 1.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit EF-hand_9 PF14658.1 KEP65819.1 - 1.4 8.8 0.0 27 4.7 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.13 KEP65819.1 - 1.9 8.3 0.5 4.4 7.1 0.3 1.7 1 0 0 1 1 1 0 Dockerin type I repeat DUF4483 PF14825.1 KEP65819.1 - 4.6 6.8 11.6 0.39 10.3 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) DUF4246 PF14033.1 KEP65819.1 - 8.5 4.8 2.4 17 3.8 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Radial_spoke PF04712.7 KEP65819.1 - 9.2 4.8 11.4 18 3.8 7.9 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein Plasmodium_Vir PF05795.6 KEP65821.1 - 0.15 11.2 0.0 0.15 11.2 0.0 2.0 2 1 0 2 2 2 0 Plasmodium vivax Vir protein PolyA_pol PF01743.15 KEP65822.1 - 2.8e-27 95.4 0.0 6.3e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PBP1_TM PF14812.1 KEP65822.1 - 0.83 9.9 7.4 2.7 8.3 0.5 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EF-hand_1 PF00036.27 KEP65825.1 - 1.1e-09 36.9 0.0 0.00053 19.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KEP65825.1 - 1.7e-09 37.6 1.1 0.00075 19.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP65825.1 - 9.5e-09 34.4 0.2 0.0028 17.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KEP65825.1 - 3e-07 29.4 1.0 0.0042 16.3 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KEP65825.1 - 0.018 14.6 0.3 5.4 6.7 0.0 3.4 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_9 PF14658.1 KEP65825.1 - 0.019 14.8 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain p450 PF00067.17 KEP65826.1 - 1.1e-36 126.3 0.0 2.3e-36 125.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 U79_P34 PF03064.11 KEP65827.1 - 0.18 11.2 7.3 0.28 10.6 5.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AP2 PF00847.15 KEP65828.1 - 7.2e-11 42.0 0.5 4e-10 39.7 0.3 2.4 2 0 0 2 2 2 1 AP2 domain SAG PF04092.8 KEP65830.1 - 1.7e-36 125.3 18.4 1.7e-24 86.5 1.4 2.4 2 1 0 2 2 2 2 SRS domain Pilin PF00114.14 KEP65830.1 - 0.4 11.4 10.4 0.99 10.1 0.6 3.2 3 0 0 3 3 3 0 Pilin (bacterial filament) AMA-1 PF02430.10 KEP65831.1 - 3.4e-57 194.3 0.2 1.8e-55 188.7 0.2 2.0 1 1 0 1 1 1 1 Apical membrane antigen 1 Smg4_UPF3 PF03467.10 KEP65832.1 - 2.1e-23 83.2 0.0 3.7e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_6 PF14259.1 KEP65832.1 - 0.00055 19.8 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP65832.1 - 0.024 14.2 0.1 0.1 12.2 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP65832.1 - 0.21 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-His_Me_endon PF05551.6 KEP65833.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease GYF PF02213.11 KEP65835.1 - 2.5e-07 30.1 0.1 4.8e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 GYF domain DnaJ PF00226.26 KEP65836.1 - 3.8e-22 77.7 1.5 1.3e-21 76.1 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain DED PF01335.16 KEP65836.1 - 0.032 14.3 0.8 7.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Death effector domain OHCU_decarbox PF09349.5 KEP65836.1 - 0.23 11.7 8.0 0.64 10.2 2.7 2.6 2 1 0 2 2 2 0 OHCU decarboxylase DUF607 PF04678.8 KEP65836.1 - 0.41 10.5 5.8 1.1 9.1 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Sigma70_ner PF04546.8 KEP65836.1 - 2.2 7.8 18.0 0.098 12.2 0.8 2.9 2 1 1 3 3 3 0 Sigma-70, non-essential region DUF4407 PF14362.1 KEP65836.1 - 7.7 5.3 14.4 6.5 5.6 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA PF00004.24 KEP65837.1 - 2.9e-43 147.2 0.0 9.6e-43 145.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KEP65837.1 - 2e-22 78.8 0.0 5.7e-22 77.3 0.0 1.8 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KEP65837.1 - 7.7e-11 41.7 1.9 7.7e-11 41.7 1.3 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 KEP65837.1 - 3.6e-06 26.2 0.0 6.6e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEP65837.1 - 6.1e-06 26.3 0.1 0.0002 21.3 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KEP65837.1 - 9.2e-06 25.4 0.0 4e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEP65837.1 - 1.2e-05 26.1 0.0 3.4e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEP65837.1 - 1.2e-05 24.8 0.4 0.026 13.9 0.2 2.6 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 KEP65837.1 - 1.2e-05 25.4 0.1 0.00041 20.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEP65837.1 - 2.3e-05 23.9 0.0 5.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KEP65837.1 - 0.00014 21.7 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP65837.1 - 0.00018 21.4 0.0 0.0004 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KEP65837.1 - 0.00034 20.5 0.0 0.00072 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KEP65837.1 - 0.0004 20.0 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KEP65837.1 - 0.0032 16.2 0.0 0.0045 15.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 KEP65837.1 - 0.0038 16.2 0.0 0.006 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KEP65837.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEP65837.1 - 0.0069 16.3 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KEP65837.1 - 0.013 14.7 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KEP65837.1 - 0.015 14.9 0.0 0.33 10.5 0.0 2.6 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 KEP65837.1 - 0.015 14.4 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEP65837.1 - 0.017 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.10 KEP65837.1 - 0.018 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 KEP65837.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KEP65837.1 - 0.023 13.7 0.1 0.19 10.8 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 KEP65837.1 - 0.037 13.7 0.0 0.44 10.2 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 KEP65837.1 - 0.075 12.5 0.0 0.3 10.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 KEP65837.1 - 0.078 12.0 0.1 1.2 8.1 0.0 2.2 1 1 1 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 KEP65837.1 - 0.13 12.2 0.0 0.41 10.6 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KEP65837.1 - 0.23 10.2 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HEAT PF02985.17 KEP65838.1 - 6e-18 63.2 25.7 0.024 14.6 0.1 9.2 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.1 KEP65838.1 - 1.8e-13 50.6 17.0 1.7e-06 28.1 0.3 6.9 5 2 0 6 6 6 2 HEAT repeats CLASP_N PF12348.3 KEP65838.1 - 0.00045 19.6 0.0 0.65 9.3 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.1 KEP65838.1 - 0.0042 17.5 1.3 0.0042 17.5 0.9 8.4 7 2 1 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 KEP65838.1 - 0.082 11.2 0.1 5.7 5.1 0.0 3.2 3 1 0 3 3 3 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KEP65838.1 - 0.11 12.9 0.0 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 KEP65838.1 - 0.38 10.7 5.2 10 6.2 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion TPR_16 PF13432.1 KEP65839.1 - 0.00046 20.7 16.5 0.44 11.2 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEP65839.1 - 0.00097 18.7 0.1 12 5.6 0.0 4.7 5 0 0 5 5 5 1 TPR repeat TPR_2 PF07719.12 KEP65839.1 - 0.0021 17.8 1.7 7.4 6.7 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP65839.1 - 0.014 15.6 10.6 3.2 8.1 0.2 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP65839.1 - 0.018 14.6 0.9 4.3 7.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEP65839.1 - 0.074 13.5 0.2 0.074 13.5 0.1 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat FERM_M PF00373.13 KEP65839.1 - 0.082 13.0 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 FERM central domain TPR_14 PF13428.1 KEP65839.1 - 1.5 9.6 26.9 0.76 10.5 0.1 7.5 8 2 2 10 10 10 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.14 KEP65840.1 - 2e-12 47.2 0.3 1.8e-10 40.8 0.2 2.4 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family V-ATPase_C PF03223.10 KEP65842.1 - 1.2e-92 310.7 0.0 1.3e-92 310.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Creatininase PF02633.9 KEP65843.1 - 0.062 12.3 1.1 0.076 12.0 0.7 1.2 1 0 0 1 1 1 0 Creatinine amidohydrolase MCM PF00493.18 KEP65844.1 - 3.7e-84 282.3 0.0 1.6e-70 237.5 0.0 3.1 3 0 0 3 3 3 3 MCM2/3/5 family Mg_chelatase PF01078.16 KEP65844.1 - 4.4e-05 22.7 0.1 0.0042 16.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEP65844.1 - 5.1e-05 23.0 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEP65844.1 - 0.0091 15.9 1.6 0.12 12.3 1.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 KEP65844.1 - 0.017 14.6 0.0 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 KEP65844.1 - 0.02 14.5 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KEP65844.1 - 0.056 13.3 0.0 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEP65844.1 - 0.22 11.7 0.0 0.8 9.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CRAL_TRIO_2 PF13716.1 KEP65845.1 - 5.8e-18 65.2 0.1 1.3e-17 64.0 0.1 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Macro PF01661.16 KEP65845.1 - 6.2e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.15 KEP65845.1 - 0.0037 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Abhydrolase_5 PF12695.2 KEP65846.1 - 5.5e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP65846.1 - 0.00011 21.8 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 KEP65846.1 - 0.00022 20.8 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 KEP65846.1 - 0.021 14.2 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KEP65846.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.8 KEP65846.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HC2 PF07382.6 KEP65847.1 - 0.36 10.6 54.6 0.48 10.2 37.8 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 ABC2_membrane PF01061.19 KEP65848.1 - 6.7e-28 97.2 10.6 9.7e-28 96.7 7.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KEP65848.1 - 2.6e-26 92.5 0.0 9.4e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KEP65848.1 - 2.2e-08 34.4 0.7 5.7e-06 26.5 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEP65848.1 - 4.7e-06 26.1 0.0 0.00085 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEP65848.1 - 0.0058 16.1 0.7 0.15 11.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KEP65848.1 - 0.0097 14.9 12.2 0.014 14.4 8.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.11 KEP65848.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEP65848.1 - 0.018 15.8 0.1 0.043 14.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KEP65848.1 - 0.074 12.8 0.5 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 ArgK PF03308.11 KEP65848.1 - 0.17 10.6 0.6 0.38 9.4 0.1 1.7 2 0 0 2 2 2 0 ArgK protein AAA_23 PF13476.1 KEP65848.1 - 0.18 12.1 0.6 0.58 10.4 0.3 1.8 2 0 0 2 2 2 0 AAA domain EGF_CA PF07645.10 KEP65849.1 - 9.8e-25 86.2 83.0 3.6e-08 33.2 6.3 6.2 6 0 0 6 6 6 6 Calcium-binding EGF domain cEGF PF12662.2 KEP65849.1 - 3.2e-10 39.4 47.2 6e-05 22.5 0.5 7.0 7 0 0 7 7 7 4 Complement Clr-like EGF-like EGF_3 PF12947.2 KEP65849.1 - 3.4e-09 36.5 77.7 0.0047 16.8 4.1 6.6 6 0 0 6 6 6 5 EGF domain EGF_MSP1_1 PF12946.2 KEP65849.1 - 0.00049 19.8 4.5 0.00049 19.8 3.1 5.6 6 0 0 6 6 6 3 MSP1 EGF domain 1 EGF PF00008.22 KEP65849.1 - 0.011 15.6 7.7 0.011 15.6 5.3 7.0 7 0 0 7 7 7 0 EGF-like domain FXa_inhibition PF14670.1 KEP65849.1 - 0.066 13.3 82.8 0.11 12.6 8.1 5.9 6 0 0 6 6 6 0 Coagulation Factor Xa inhibitory site DUF1191 PF06697.7 KEP65849.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EGF_CA PF07645.10 KEP65850.1 - 5.9e-23 80.5 78.7 1.3e-10 41.1 5.9 6.4 6 0 0 6 6 6 5 Calcium-binding EGF domain EGF_3 PF12947.2 KEP65850.1 - 5.8e-15 54.9 74.2 1.6e-05 24.7 5.4 6.6 6 1 0 6 6 6 4 EGF domain EGF_MSP1_1 PF12946.2 KEP65850.1 - 1.9e-09 37.1 35.9 1.5e-06 27.8 1.8 5.7 5 0 0 5 5 5 4 MSP1 EGF domain 1 cEGF PF12662.2 KEP65850.1 - 1.3e-08 34.2 45.8 0.00012 21.5 0.8 7.0 6 1 0 6 6 6 4 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP65850.1 - 1.9e-06 27.8 69.0 0.0013 18.8 4.5 6.5 5 1 1 6 6 6 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KEP65850.1 - 1.4e-05 24.9 60.1 0.0012 18.7 3.2 6.6 6 0 0 6 6 6 4 EGF-like domain DUF2910 PF11139.3 KEP65850.1 - 0.094 11.8 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) hEGF PF12661.2 KEP65850.1 - 0.42 10.7 19.1 0.69 10.1 0.5 5.6 4 0 0 4 4 4 0 Human growth factor-like EGF GBP_PSP PF02425.10 KEP65850.1 - 2.4 7.7 8.5 0.17 11.4 0.7 3.2 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Plasmod_Pvs28 PF06247.6 KEP65850.1 - 4 6.9 55.5 0.14 11.7 18.0 4.1 1 1 2 3 3 3 0 Plasmodium ookinete surface protein Pvs28 Vps39_2 PF10367.4 KEP65851.1 - 2.9e-22 78.9 0.0 5.9e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KEP65851.1 - 3.1e-16 59.6 0.0 8.2e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KEP65851.1 - 4.7e-06 26.2 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_1 PF10366.4 KEP65851.1 - 0.02 14.9 0.1 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 EGF_CA PF07645.10 KEP65852.1 - 2.8e-20 72.0 82.2 3.3e-09 36.5 6.5 6.3 6 0 0 6 6 6 4 Calcium-binding EGF domain EGF_3 PF12947.2 KEP65852.1 - 3.6e-19 68.4 74.3 1.2e-06 28.3 8.3 6.9 6 2 0 6 6 6 5 EGF domain cEGF PF12662.2 KEP65852.1 - 9.7e-11 41.1 52.6 2.6e-07 30.1 2.1 7.1 7 2 0 7 7 7 4 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP65852.1 - 1.6e-08 34.4 74.0 0.00024 21.1 6.6 6.5 5 1 1 6 6 6 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 KEP65852.1 - 0.00012 21.9 67.1 0.0048 16.8 3.8 7.7 6 4 0 6 6 6 3 EGF-like domain EGF_MSP1_1 PF12946.2 KEP65852.1 - 0.00017 21.2 5.1 0.00017 21.2 3.5 6.2 6 0 0 6 6 6 3 MSP1 EGF domain 1 DUF1191 PF06697.7 KEP65852.1 - 0.032 13.0 0.2 0.056 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Acyl-CoA_dh_M PF02770.14 KEP65857.1 - 3.4e-09 36.0 0.1 7.8e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KEP65857.1 - 0.00059 19.9 0.2 0.0075 16.3 0.0 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain MIP-T3 PF10243.4 KEP65858.1 - 1.3e-06 27.1 26.2 1.3e-06 27.1 18.2 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Saccharop_dh PF03435.13 KEP65860.1 - 4.4e-12 45.6 0.0 7.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Mg_trans_NIPA PF05653.9 KEP65861.1 - 1.9e-10 40.1 11.1 2.4e-06 26.7 1.2 2.4 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KEP65861.1 - 4.8e-07 29.9 5.0 4.8e-07 29.9 3.5 3.3 3 0 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KEP65861.1 - 9e-05 22.5 6.2 9e-05 22.5 4.3 3.1 3 0 0 3 3 3 1 EamA-like transporter family PsbJ PF01788.12 KEP65861.1 - 0.052 13.0 0.1 0.19 11.2 0.1 2.0 1 0 0 1 1 1 0 PsbJ dCMP_cyt_deam_1 PF00383.17 KEP65862.1 - 0.0015 18.1 0.1 0.0042 16.6 0.1 1.8 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TraC_F_IV PF11130.3 KEP65862.1 - 0.052 12.9 1.2 0.1 12.0 0.1 2.0 3 0 0 3 3 3 0 F pilus assembly Type-IV secretion system for plasmid transfer SAG PF04092.8 KEP65863.1 - 1.2e-23 83.8 21.0 4.3e-12 46.4 4.2 2.1 2 0 0 2 2 2 2 SRS domain OapA_N PF08525.6 KEP65863.1 - 4.7 7.1 8.8 2.5 7.9 0.6 2.4 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif SAG PF04092.8 KEP65864.1 - 1.2e-23 83.8 18.3 2.3e-12 47.4 2.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP65865.1 - 1.3e-15 57.8 15.5 8.6e-09 35.8 4.4 3.1 3 0 0 3 3 3 2 SRS domain SAG PF04092.8 KEP65866.1 - 7.3e-25 87.7 21.4 1.6e-14 54.3 5.3 2.1 2 0 0 2 2 2 2 SRS domain INCENP_ARK-bind PF03941.10 KEP65867.1 - 5.9e-05 22.8 1.2 8e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Snf7 PF03357.16 KEP65868.1 - 4.9e-11 42.3 3.8 6.4e-11 41.9 2.6 1.1 1 0 0 1 1 1 1 Snf7 Pkip-1 PF06878.6 KEP65868.1 - 0.042 13.7 0.5 0.097 12.5 0.3 1.6 1 1 0 1 1 1 0 Pkip-1 protein Ist1 PF03398.9 KEP65868.1 - 0.11 11.8 0.8 0.25 10.7 0.6 1.6 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway TraF_2 PF13729.1 KEP65868.1 - 0.29 9.8 2.4 5.7 5.6 0.0 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein SAG PF04092.8 KEP65869.1 - 4.5e-14 52.8 25.7 3e-07 30.8 7.9 2.9 2 1 0 2 2 2 2 SRS domain SAG PF04092.8 KEP65870.1 - 1.1e-10 42.0 8.6 5.8e-09 36.4 3.6 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP65871.1 - 0.0041 17.5 2.3 0.0063 16.8 1.6 1.3 1 0 0 1 1 1 1 SRS domain MRP-S28 PF10213.4 KEP65871.1 - 0.17 11.9 0.8 1.1 9.3 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit protein FliD_N PF02465.13 KEP65871.1 - 0.67 10.3 5.2 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SAG PF04092.8 KEP65872.1 - 3.8e-19 69.2 16.3 1.2e-09 38.5 3.5 2.1 2 0 0 2 2 2 2 SRS domain Sigma70_r1_1 PF03979.9 KEP65873.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 DUF667 PF05018.8 KEP65874.1 - 3.2e-102 339.6 0.8 3.7e-102 339.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) NUDIX_2 PF13869.1 KEP65875.1 - 0.42 9.9 0.7 0.72 9.1 0.5 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase OmpH PF03938.9 KEP65877.1 - 1.2 9.0 14.1 0.83 9.5 1.8 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AlaDh_PNT_N PF05222.10 KEP65878.1 - 1.7e-42 144.6 0.0 2.7e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KEP65878.1 - 1.6e-40 138.3 0.1 3.1e-40 137.4 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KEP65878.1 - 4e-06 26.1 0.0 2e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KEP65878.1 - 0.0004 20.4 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KEP65878.1 - 0.001 18.0 3.5 0.002 17.0 2.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KEP65878.1 - 0.0012 18.8 0.1 0.018 15.0 0.0 2.6 2 1 1 3 3 3 1 TrkA-N domain Pyr_redox PF00070.22 KEP65878.1 - 0.0016 18.8 0.3 0.003 17.9 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEP65878.1 - 0.0019 18.0 0.1 0.0028 17.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KEP65878.1 - 0.0029 16.9 0.0 0.023 14.0 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 KEP65878.1 - 0.0031 16.4 1.0 0.0042 16.0 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KEP65878.1 - 0.0082 15.8 0.9 0.015 14.9 0.3 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KEP65878.1 - 0.0096 15.9 1.5 0.052 13.5 0.9 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KEP65878.1 - 0.013 15.7 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KEP65878.1 - 0.2 10.6 3.1 0.24 10.4 1.5 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 KEP65878.1 - 0.34 9.7 3.9 0.57 8.9 2.7 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KEP65878.1 - 0.4 9.0 2.2 0.55 8.6 1.6 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 KEP65878.1 - 1.4 7.8 6.6 2.1 7.3 4.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UPF0160 PF03690.8 KEP65879.1 - 1.1e-99 333.8 0.0 1.7e-62 211.7 0.0 2.6 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0160) Rapsyn_N PF10579.4 KEP65881.1 - 0.0052 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Rapsyn N-terminal myristoylation and linker region TPR_12 PF13424.1 KEP65881.1 - 0.049 13.5 1.1 0.17 11.8 0.8 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat LMF1 PF06762.9 KEP65882.1 - 3.4e-165 549.5 5.6 5e-165 548.9 3.9 1.3 1 0 0 1 1 1 1 Lipase maturation factor LMF1 PF06762.9 KEP65883.1 - 1.2e-140 468.6 0.0 2.9e-140 467.4 0.0 1.7 1 1 0 1 1 1 1 Lipase maturation factor Pkinase PF00069.20 KEP65884.1 - 2.8e-71 239.6 0.0 4e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP65884.1 - 3.6e-32 111.4 0.0 5.3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KEP65884.1 - 0.007 16.5 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 PH domain SLA_LP_auto_ag PF05889.8 KEP65885.1 - 8.3e-112 373.4 0.0 1.1e-106 356.6 0.0 3.0 2 1 0 2 2 2 2 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 KEP65885.1 - 0.0022 17.1 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KEP65885.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Takusan PF04822.8 KEP65886.1 - 0.0091 15.7 0.1 1.5 8.6 0.1 2.6 2 0 0 2 2 2 2 Takusan IF4E PF01652.13 KEP65887.1 - 1.3e-31 109.3 0.0 2.2e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RNA_polI_A34 PF08208.6 KEP65887.1 - 2.8 7.5 22.2 0.74 9.4 2.9 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 WD40 PF00400.27 KEP65888.1 - 4.2e-11 42.2 11.6 4.3e-05 23.2 0.0 5.6 7 0 0 7 7 7 2 WD domain, G-beta repeat PCMT PF01135.14 KEP65889.1 - 4.8e-61 205.9 0.1 1.3e-55 188.1 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KEP65889.1 - 2.1e-05 25.0 0.0 5.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP65889.1 - 0.00018 21.1 0.0 0.0004 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP65889.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KEP65889.1 - 0.043 13.1 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KEP65889.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KEP65889.1 - 0.076 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KEP65889.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEP65889.1 - 0.11 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KEP65889.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KEP65889.1 - 0.22 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF3492 PF11997.3 KEP65891.1 - 0.15 11.6 0.5 0.31 10.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) TFIID_30kDa PF03540.8 KEP65892.1 - 7.9e-06 25.6 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Prefoldin PF02996.12 KEP65893.1 - 2.2e-24 85.3 2.0 3.2e-24 84.8 1.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit GAS PF13851.1 KEP65893.1 - 0.0075 15.4 8.0 0.078 12.1 1.8 2.0 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Prefoldin_3 PF13758.1 KEP65893.1 - 0.011 15.4 0.3 0.024 14.4 0.2 1.6 1 1 0 1 1 1 0 Prefoldin subunit DUF970 PF06153.6 KEP65893.1 - 0.05 13.5 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF970) Prefoldin_2 PF01920.15 KEP65893.1 - 0.11 12.2 10.0 0.3 10.8 2.3 2.5 2 1 0 2 2 2 0 Prefoldin subunit ISG65-75 PF11727.3 KEP65893.1 - 0.22 10.5 2.2 0.43 9.5 0.3 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein V_ATPase_I PF01496.14 KEP65893.1 - 0.24 9.2 2.1 0.36 8.6 1.4 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family YscO PF07321.7 KEP65893.1 - 1.9 8.3 14.4 0.49 10.2 1.5 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO CENP-F_leu_zip PF10473.4 KEP65893.1 - 2.8 7.7 10.2 4.1 7.2 0.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 KEP65893.1 - 7.2 6.4 8.1 12 5.7 0.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NOB1_Zn_bind PF08772.6 KEP65894.1 - 0.044 13.6 2.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like PI-PLC-X PF00388.14 KEP65896.1 - 8e-05 22.0 0.0 0.00022 20.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain RHD3 PF05879.7 KEP65897.1 - 4.1e-125 418.4 0.0 5e-125 418.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KEP65897.1 - 4.9e-06 25.8 0.0 1.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 KEP65897.1 - 9.3e-05 22.3 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEP65897.1 - 0.0023 17.7 0.1 0.0052 16.6 0.1 1.6 1 0 0 1 1 1 1 Dynamin family DUF1546 PF07571.8 KEP65897.1 - 0.0075 16.3 0.0 0.026 14.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) AAA_23 PF13476.1 KEP65897.1 - 0.048 13.9 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEP65897.1 - 0.071 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KEP65897.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phage_GPL PF05926.6 KEP65897.1 - 0.29 10.9 2.9 1.9 8.3 0.1 3.5 4 0 0 4 4 4 0 Phage head completion protein (GPL) DNA_ligase_aden PF01653.13 KEP65898.1 - 0.0005 19.1 0.1 0.00071 18.6 0.1 1.1 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain TFIIF_alpha PF05793.7 KEP65899.1 - 0.079 11.3 18.0 0.099 10.9 12.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 KEP65899.1 - 1.1 7.6 16.4 1.3 7.4 11.4 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KEP65899.1 - 1.9 6.3 15.9 2 6.1 11.1 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 KEP65899.1 - 2.4 7.6 5.9 3 7.3 4.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.5 KEP65899.1 - 4.9 6.1 16.7 5.7 5.8 11.6 1.0 1 0 0 1 1 1 0 BUD22 DUF4407 PF14362.1 KEP65899.1 - 5.6 5.8 6.0 6.6 5.5 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_ligase_aden PF01653.13 KEP65900.1 - 0.00036 19.5 0.0 0.44 9.4 0.0 2.1 2 0 0 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.11 KEP65901.1 - 8.8e-11 41.3 0.0 1.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain DNA_ligase_aden PF01653.13 KEP65901.1 - 6e-05 22.1 0.0 9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain RAP1 PF07218.6 KEP65902.1 - 6.3 4.7 6.7 6.8 4.6 4.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CBM_20 PF00686.14 KEP65904.1 - 1.5e-18 66.1 0.1 2.2e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 Starch binding domain CBM_48 PF02922.13 KEP65904.1 - 0.014 15.4 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF1374 PF07118.6 KEP65904.1 - 0.09 12.8 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) CLTH PF10607.4 KEP65905.1 - 3.3e-25 88.4 0.9 4.3e-25 88.0 0.6 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KEP65905.1 - 8.8e-06 25.2 0.1 2.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 LisH ThiF PF00899.16 KEP65906.1 - 7.4e-32 110.0 6.7 2.1e-22 79.3 0.0 4.1 4 0 0 4 4 4 3 ThiF family UBACT PF02134.16 KEP65906.1 - 2.2e-14 52.7 0.1 7.8e-11 41.4 0.0 2.8 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEP65906.1 - 1.6e-09 37.0 0.0 3.7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBA_e1_C PF09358.5 KEP65906.1 - 1.7e-05 25.0 0.0 0.022 14.9 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-activating enzyme e1 C-terminal domain RIC1 PF07064.8 KEP65908.1 - 2.6e-12 46.7 0.2 5.8e-11 42.3 0.0 2.6 2 1 0 2 2 2 1 RIC1 FliX PF10768.4 KEP65908.1 - 0.54 10.4 5.4 0.077 13.2 0.5 2.0 2 0 0 2 2 2 0 Class II flagellar assembly regulator KH_1 PF00013.24 KEP65909.1 - 7.3e-09 35.1 0.1 1.4e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KEP65909.1 - 0.00066 19.2 0.3 0.0018 17.8 0.2 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 KEP65909.1 - 0.0019 17.8 2.2 0.35 10.5 0.0 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 KEP65909.1 - 0.004 17.0 7.0 0.012 15.5 0.8 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 KEP65909.1 - 0.013 14.9 5.8 0.14 11.6 0.9 3.0 1 1 1 2 2 2 0 Zinc knuckle DUF4206 PF13901.1 KEP65909.1 - 0.027 14.0 0.3 0.04 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zf-CCHC_3 PF13917.1 KEP65909.1 - 0.044 13.5 2.9 0.22 11.3 0.0 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 KEP65909.1 - 0.28 10.8 5.1 1.1 9.0 0.1 3.1 3 0 0 3 3 3 0 Zinc knuckle Peptidase_M16_C PF05193.16 KEP65910.1 - 0.0021 17.7 0.0 0.71 9.5 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEP65910.1 - 0.066 12.9 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) UCH PF00443.24 KEP65911.1 - 2.6e-23 82.4 0.0 5.3e-12 45.4 0.0 2.7 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP65911.1 - 0.0028 17.1 0.0 0.37 10.1 0.0 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase SF3b10 PF07189.6 KEP65912.1 - 7.5e-33 112.1 0.1 9e-33 111.9 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) ATP-synt_Eps PF04627.8 KEP65913.1 - 1.8e-11 43.3 0.1 1.8e-11 43.3 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Ribosomal_L30 PF00327.15 KEP65914.1 - 8.6e-16 57.2 2.4 1.3e-15 56.7 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 KEP65914.1 - 5.6e-11 42.2 13.2 1.1e-10 41.3 9.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain CENP-Q PF13094.1 KEP65914.1 - 0.024 14.6 0.9 0.035 14.1 0.6 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-met2 PF12907.2 KEP65915.1 - 5.3e-20 71.1 5.4 5.3e-20 71.1 3.8 1.7 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.9 KEP65915.1 - 5e-05 23.9 6.2 0.0001 22.9 4.3 1.5 1 0 0 1 1 1 1 4F5 protein family LSM PF01423.17 KEP65916.1 - 2.2e-16 59.1 0.1 2.6e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEP65916.1 - 0.014 15.2 0.1 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Myosin_head PF00063.16 KEP65917.1 - 6.2e-175 583.1 0.0 8.8e-175 582.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.12 KEP65917.1 - 8.2e-20 70.8 0.2 8.4e-19 67.6 0.0 2.8 3 0 0 3 3 3 1 MyTH4 domain AAA_22 PF13401.1 KEP65917.1 - 0.025 14.7 0.0 0.28 11.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain IQ PF00612.22 KEP65917.1 - 0.86 9.4 7.3 0.18 11.5 1.8 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif tRNA_m1G_MT PF01746.16 KEP65918.1 - 2.8e-18 66.1 0.0 2.9e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase SOBP PF15279.1 KEP65918.1 - 0.69 10.2 15.5 0.039 14.3 6.3 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein Hex_IIIa PF02455.11 KEP65918.1 - 4.7 5.7 8.4 9.4 4.7 5.8 1.5 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Ndc1_Nup PF09531.5 KEP65918.1 - 6.5 5.0 9.3 8.8 4.6 6.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L1 PF00687.16 KEP65919.1 - 3e-43 147.7 0.5 4.4e-43 147.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF382 PF04037.8 KEP65920.1 - 7e-54 181.0 0.1 1.6e-53 179.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 KEP65920.1 - 3e-19 68.1 6.1 7.2e-19 66.9 4.2 1.7 1 0 0 1 1 1 1 PSP CTD PF12815.2 KEP65920.1 - 0.0058 17.0 3.9 0.0058 17.0 2.7 3.0 2 1 1 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Nop14 PF04147.7 KEP65920.1 - 1.2 7.0 22.1 0.095 10.6 11.8 1.8 2 0 0 2 2 2 0 Nop14-like family Alg6_Alg8 PF03155.10 KEP65921.1 - 1e-93 314.7 23.7 1.5e-36 126.3 0.1 4.0 4 0 0 4 4 4 4 ALG6, ALG8 glycosyltransferase family Sedlin_N PF04628.8 KEP65922.1 - 3.5e-19 68.9 0.0 4.1e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KEP65922.1 - 0.014 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Sybindin-like family AKNA PF12443.3 KEP65923.1 - 0.031 14.2 4.8 0.077 13.0 1.0 2.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF3584 PF12128.3 KEP65923.1 - 0.039 11.2 10.4 0.047 11.0 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SDH_alpha PF03313.10 KEP65923.1 - 0.052 12.5 2.2 0.06 12.3 1.5 1.0 1 0 0 1 1 1 0 Serine dehydratase alpha chain Tis11B_N PF04553.7 KEP65923.1 - 0.076 13.2 1.2 0.099 12.8 0.9 1.5 1 1 0 1 1 1 0 Tis11B like protein, N terminus Fmp27_WPPW PF10359.4 KEP65923.1 - 0.23 9.8 10.1 0.25 9.7 7.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlgN PF05130.7 KEP65923.1 - 0.24 11.6 7.1 0.3 11.3 4.9 1.1 1 0 0 1 1 1 0 FlgN protein DUF4629 PF15442.1 KEP65923.1 - 0.3 11.2 6.6 0.34 11.0 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) APG6 PF04111.7 KEP65923.1 - 0.57 9.1 11.3 0.62 9.0 7.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DOG1 PF14144.1 KEP65923.1 - 1.2 9.1 3.4 6.7 6.8 1.6 2.0 2 0 0 2 2 2 0 Seed dormancy control GvpL_GvpF PF06386.6 KEP65923.1 - 1.6 8.2 8.8 1.9 8.0 6.1 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ax_dynein_light PF10211.4 KEP65923.1 - 3.6 7.3 11.9 6.7 6.5 8.3 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain DUF4337 PF14235.1 KEP65923.1 - 4.2 7.1 10.3 4.9 6.9 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.1 KEP65923.1 - 5 5.9 9.3 6.7 5.5 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.7 KEP65923.1 - 5.3 7.4 10.4 6.5 7.2 5.2 2.0 1 1 1 2 2 2 0 SlyX IncA PF04156.9 KEP65923.1 - 8.4 5.9 9.0 10 5.6 6.3 1.2 1 0 0 1 1 1 0 IncA protein Mito_carr PF00153.22 KEP65924.1 - 2.3e-49 165.0 6.8 5.4e-18 64.4 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Ank_5 PF13857.1 KEP65924.1 - 0.092 13.0 0.0 0.76 10.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Mmp37 PF09139.6 KEP65927.1 - 2.3e-56 191.2 0.0 2.6e-49 168.0 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial matrix Mmp37 RPAP1_C PF08620.5 KEP65932.1 - 1.3e-16 60.1 0.1 3.3e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KEP65932.1 - 1.2e-05 24.7 4.7 3.7e-05 23.2 3.2 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal Peptidase_S8 PF00082.17 KEP65934.1 - 1.4e-49 168.7 4.8 2.6e-49 167.9 3.3 1.4 1 0 0 1 1 1 1 Subtilase family Glycophorin_A PF01102.13 KEP65934.1 - 0.0044 16.7 0.0 0.024 14.4 0.0 2.4 1 0 0 1 1 1 1 Glycophorin A Shisa PF13908.1 KEP65934.1 - 0.012 15.8 1.8 0.018 15.2 0.0 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Mucin PF01456.12 KEP65934.1 - 0.18 11.5 0.0 0.18 11.5 0.0 3.3 3 1 0 3 3 3 0 Mucin-like glycoprotein FAM176 PF14851.1 KEP65934.1 - 0.26 10.9 1.4 1.2 8.7 0.9 2.2 1 1 0 1 1 1 0 FAM176 family DUF4448 PF14610.1 KEP65934.1 - 0.39 10.1 3.0 16 4.8 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4448) DUF2839 PF10999.3 KEP65934.1 - 6.1 6.9 5.5 12 5.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) HD-ZIP_N PF04618.7 KEP65939.1 - 0.00037 20.9 2.1 0.0016 18.9 1.4 2.1 1 0 0 1 1 1 1 HD-ZIP protein N terminus DUF1395 PF07160.7 KEP65939.1 - 0.028 13.9 0.9 0.06 12.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) DSPn PF14671.1 KEP65942.1 - 2e-50 170.4 0.0 5.2e-50 169.1 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KEP65942.1 - 1.3e-11 44.2 0.0 4.3e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 KEP65942.1 - 1.6e-06 27.6 0.0 3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEP65942.1 - 5.2e-06 25.9 0.0 8.3e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KEP65942.1 - 0.00063 20.0 0.1 0.0057 16.9 0.1 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KEP65942.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Rhodanese PF00581.15 KEP65943.1 - 3.9e-15 56.1 0.0 6.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Clat_adaptor_s PF01217.15 KEP65944.1 - 3.7e-44 149.8 3.1 4.1e-44 149.7 2.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain EGF PF00008.22 KEP65945.1 - 0.071 13.0 3.5 0.33 10.9 2.5 2.2 1 1 0 1 1 1 0 EGF-like domain Sclerostin PF05463.6 KEP65945.1 - 0.086 12.3 0.1 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Sclerostin (SOST) AAA_11 PF13086.1 KEP65946.1 - 2.4e-24 86.2 0.0 2.4e-24 86.2 0.0 4.2 3 2 0 3 3 3 1 AAA domain AAA_12 PF13087.1 KEP65946.1 - 1.2e-23 83.5 0.0 3.2e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEP65946.1 - 5.6e-08 32.4 0.0 2e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KEP65946.1 - 3.9e-05 23.4 0.0 0.00017 21.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEP65946.1 - 0.002 17.5 0.1 0.0067 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEP65946.1 - 0.0021 18.2 0.0 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KEP65946.1 - 0.0036 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.24 KEP65946.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KEP65946.1 - 0.13 11.7 0.0 0.5 9.8 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 KEP65946.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Transket_pyr PF02779.19 KEP65947.1 - 2.2e-42 144.5 0.0 4e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEP65947.1 - 2.1e-35 121.3 0.0 3.6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain BSD PF03909.12 KEP65948.1 - 0.0011 18.7 0.1 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 BSD domain CKS PF01111.14 KEP65949.1 - 0.12 12.2 0.1 0.36 10.6 0.0 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit WW PF00397.21 KEP65950.1 - 8.4e-06 25.5 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 WW domain SNF PF00209.13 KEP65951.1 - 2.8e-121 405.5 32.3 1.8e-117 393.0 21.1 3.0 2 1 0 2 2 2 2 Sodium:neurotransmitter symporter family EGF_2 PF07974.8 KEP65951.1 - 0.3 11.2 31.6 0.15 12.2 6.6 4.0 3 0 0 3 3 3 0 EGF-like domain ABC_membrane_2 PF06472.10 KEP65952.1 - 1.5e-64 217.8 1.4 2.3e-64 217.2 1.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KEP65952.1 - 9.1e-20 71.3 0.0 2.4e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEP65952.1 - 0.00079 19.4 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KEP65952.1 - 0.0016 17.7 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 KEP65952.1 - 0.0046 16.6 0.3 0.65 9.6 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 KEP65952.1 - 0.019 14.3 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 KEP65952.1 - 0.081 12.3 0.6 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain TraG-D_C PF12696.2 KEP65952.1 - 0.1 12.5 0.0 0.4 10.5 0.0 2.1 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG AAA_29 PF13555.1 KEP65952.1 - 0.19 11.3 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 KEP65952.1 - 0.29 10.6 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 KEP65952.1 - 0.42 10.8 0.2 0.79 10.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KEP65953.1 - 1.4e-12 47.5 0.0 3.8e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP65953.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 KEP65953.1 - 0.057 12.5 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 AIG1 family TAN PF11640.3 KEP65953.1 - 0.11 12.2 0.3 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Dynamin_N PF00350.18 KEP65953.1 - 3.2 7.5 4.3 5.1 6.8 0.0 3.0 3 0 0 3 3 3 0 Dynamin family HABP4_PAI-RBP1 PF04774.10 KEP65954.1 - 0.00015 22.1 6.3 0.00018 21.9 4.4 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Ribosomal_TL5_C PF14693.1 KEP65955.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.14 KEP65955.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L25p family AAR2 PF05282.6 KEP65956.1 - 2.4e-51 174.8 0.0 1.2e-26 93.5 0.0 2.3 2 0 0 2 2 2 2 AAR2 protein RF-1 PF00472.15 KEP65957.1 - 2.4e-33 114.3 0.3 2.4e-33 114.3 0.2 2.0 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 KEP65957.1 - 6.8e-23 80.5 0.1 1.7e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 PCRF domain Herpes_US9 PF06072.6 KEP65959.1 - 0.01 15.6 1.6 0.026 14.3 0.1 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Radical_SAM PF04055.16 KEP65959.1 - 0.018 15.2 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Radical SAM superfamily DUF3357 PF11837.3 KEP65959.1 - 0.019 14.7 0.7 0.041 13.7 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Protocadherin PF08374.6 KEP65959.1 - 0.019 14.5 1.8 0.019 14.5 1.2 2.0 1 1 1 2 2 2 0 Protocadherin DUF2422 PF10337.4 KEP65959.1 - 0.033 12.9 4.0 0.045 12.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) TT_ORF2 PF02957.10 KEP65959.1 - 0.065 13.9 0.4 0.065 13.9 0.3 1.6 2 0 0 2 2 1 0 TT viral ORF2 FliD_C PF07195.7 KEP65959.1 - 0.11 11.7 9.6 0.19 10.9 6.6 1.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus V_ATPase_I PF01496.14 KEP65959.1 - 0.11 10.3 6.1 0.14 10.0 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3232 PF11554.3 KEP65959.1 - 0.47 10.3 4.4 1.7 8.5 3.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3232) NifW PF03206.9 KEP65959.1 - 0.49 10.5 8.2 0.44 10.6 1.1 2.7 1 1 2 3 3 3 0 Nitrogen fixation protein NifW Apolipoprotein PF01442.13 KEP65959.1 - 1.1 8.7 11.4 0.79 9.1 4.4 2.0 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Laminin_II PF06009.7 KEP65959.1 - 1.1 8.9 11.3 0.22 11.2 1.8 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF2317 PF10079.4 KEP65959.1 - 1.3 7.5 10.4 1.7 7.1 7.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF342 PF03961.8 KEP65959.1 - 1.3 7.3 13.6 3.4 5.9 9.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 KEP65959.1 - 1.5 7.6 6.2 2.6 6.9 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4654 PF15547.1 KEP65959.1 - 1.7 8.9 9.2 0.26 11.6 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4654) Spectrin PF00435.16 KEP65959.1 - 1.7 8.9 7.9 0.97 9.7 1.5 2.3 1 1 1 2 2 2 0 Spectrin repeat Syntaxin PF00804.20 KEP65959.1 - 2.9 8.0 9.2 6.1 7.0 6.3 1.5 1 1 0 1 1 1 0 Syntaxin U1snRNP70_N PF12220.3 KEP65959.1 - 3.4 8.0 14.1 1.6 9.1 3.1 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal IncA PF04156.9 KEP65959.1 - 3.7 7.0 10.7 79 2.7 7.4 2.2 1 1 0 1 1 1 0 IncA protein SPOUT_MTase PF02590.12 KEP65959.1 - 4.9 6.8 12.7 2.6 7.7 3.1 2.7 1 1 2 3 3 3 0 Predicted SPOUT methyltransferase Muted PF14942.1 KEP65959.1 - 4.9 7.0 11.4 0.56 10.0 3.8 1.9 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein DivIC PF04977.10 KEP65959.1 - 7.8 6.0 10.4 6.3 6.3 0.1 3.1 2 1 1 3 3 3 0 Septum formation initiator APG6 PF04111.7 KEP65959.1 - 8.3 5.3 13.9 17 4.3 9.7 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Fmp27_SW PF10305.4 KEP65960.1 - 0.019 15.3 1.9 0.022 15.1 1.0 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FHIPEP PF00771.15 KEP65960.1 - 0.02 13.2 0.0 0.022 13.0 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family DUF964 PF06133.6 KEP65960.1 - 0.055 13.4 6.9 0.047 13.7 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF964) ApoO PF09769.4 KEP65960.1 - 0.19 11.4 0.5 0.25 11.0 0.3 1.2 1 0 0 1 1 1 0 Apolipoprotein O DUF2203 PF09969.4 KEP65960.1 - 0.34 11.1 3.9 0.54 10.4 2.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ING PF12998.2 KEP65960.1 - 0.77 10.0 7.9 1.2 9.4 5.5 1.4 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF2031 PF09592.5 KEP65960.1 - 1 8.4 11.7 1.4 8.0 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Seryl_tRNA_N PF02403.17 KEP65960.1 - 1.1 9.2 16.1 0.28 11.2 7.5 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_B PF00430.13 KEP65960.1 - 1.5 8.6 12.2 3 7.6 6.4 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) vATP-synt_E PF01991.13 KEP65960.1 - 1.7 7.9 13.1 2.2 7.5 9.1 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit CCDC-167 PF15188.1 KEP65960.1 - 2.4 8.1 8.7 0.21 11.5 2.1 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 BTV_NS2 PF04514.7 KEP65960.1 - 2.8 6.7 10.7 3.5 6.4 7.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Fzo_mitofusin PF04799.8 KEP65960.1 - 2.9 7.2 7.4 1.2 8.4 1.3 2.0 1 1 1 2 2 2 0 fzo-like conserved region V_ATPase_I PF01496.14 KEP65960.1 - 3.5 5.3 8.5 4.5 4.9 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.15 KEP65960.1 - 6.9 4.4 11.7 7.9 4.2 8.1 1.0 1 0 0 1 1 1 0 Hsp70 protein TPR_12 PF13424.1 KEP65961.1 - 3.1e-11 43.0 20.2 0.0033 17.3 0.1 8.2 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEP65961.1 - 2.5e-09 36.6 9.6 0.32 10.6 0.0 7.6 8 1 1 9 9 9 3 TPR repeat Apc3 PF12895.2 KEP65961.1 - 5.1e-09 36.1 7.3 1.2e-05 25.3 0.0 5.2 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEP65961.1 - 3e-08 33.4 14.6 0.0016 18.2 0.0 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEP65961.1 - 5.4e-08 32.1 10.6 0.12 12.3 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEP65961.1 - 2.8e-07 29.8 3.9 0.39 10.3 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEP65961.1 - 4.1e-06 26.1 9.4 1.4 8.9 0.2 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP65961.1 - 0.00019 21.6 15.0 0.72 10.2 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEP65961.1 - 0.00021 21.5 8.5 21 5.8 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEP65961.1 - 0.00045 19.8 0.0 3.4 7.6 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEP65961.1 - 0.00048 20.7 37.5 0.041 14.5 0.2 9.0 6 3 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEP65961.1 - 0.028 15.0 46.9 2.3 9.0 0.2 11.6 8 3 4 12 12 11 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEP65961.1 - 0.88 9.5 21.6 4.2 7.4 0.3 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat SH3BGR PF04908.10 KEP65964.1 - 0.13 12.1 0.0 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Aha1_N PF09229.6 KEP65965.1 - 5.1e-19 68.4 0.0 1.3e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_11 PF13414.1 KEP65965.1 - 9.1e-09 34.8 2.4 3.5e-05 23.3 0.2 2.9 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 KEP65965.1 - 7.5e-05 22.3 7.3 0.2 11.6 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEP65965.1 - 0.00015 22.3 10.1 0.00038 21.0 3.8 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP65965.1 - 0.00034 20.4 1.1 0.00074 19.3 0.4 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEP65965.1 - 0.015 15.6 1.8 0.89 10.1 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP65965.1 - 0.032 14.8 10.2 0.078 13.6 0.8 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEP65965.1 - 0.041 14.2 5.2 0.23 11.8 0.3 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEP65965.1 - 0.074 12.9 0.4 1.1 9.2 0.0 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 KEP65965.1 - 0.13 11.8 6.4 1.3 8.7 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Proteasome PF00227.21 KEP65966.1 - 4.2e-37 127.2 0.0 4.7e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RRM_5 PF13893.1 KEP65969.1 - 4.7e-08 32.7 0.0 0.00016 21.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP65969.1 - 0.00019 21.0 0.0 0.0074 15.9 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP65969.1 - 0.001 18.9 0.0 0.0047 16.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cyto_heme_lyase PF01265.12 KEP65970.1 - 1.2e-61 208.5 0.0 1.4e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF2890 PF11081.3 KEP65971.1 - 4.9 7.1 10.0 8.5 6.3 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SelR PF01641.13 KEP65973.1 - 6.7e-42 142.1 0.1 9.3e-42 141.6 0.0 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KEP65973.1 - 0.0078 16.0 1.2 0.082 12.7 1.1 2.4 1 1 1 2 2 2 2 Double zinc ribbon CBF PF03914.12 KEP65974.1 - 2.3e-15 56.4 0.3 2.3e-15 56.4 0.2 2.7 2 1 0 2 2 2 1 CBF/Mak21 family EMG1 PF03587.9 KEP65975.1 - 3.3e-56 189.7 0.0 3.8e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PhyH PF05721.8 KEP65976.1 - 5.2e-09 36.4 0.0 3.8e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ribosomal_L19 PF01245.15 KEP65977.1 - 2.7e-14 52.9 0.0 5.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 GMC_oxred_N PF00732.14 KEP65978.1 - 2.3e-61 207.5 0.0 7.8e-60 202.5 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEP65978.1 - 1e-30 106.9 0.2 1.9e-11 44.4 0.1 3.5 3 0 0 3 3 3 3 GMC oxidoreductase eIF-3_zeta PF05091.7 KEP65978.1 - 2.4 6.6 5.6 5 5.6 3.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CRT-like PF08627.5 KEP65980.1 - 3.8e-09 36.5 0.2 7.9e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 CRT-like EamA PF00892.15 KEP65980.1 - 3.7e-06 26.9 3.7 3.7e-06 26.9 2.6 2.8 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KEP65980.1 - 7.6e-05 22.8 5.4 7.6e-05 22.8 3.7 2.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 KEP65980.1 - 0.00015 20.7 4.6 0.00015 20.7 3.2 2.1 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Nuc_sug_transp PF04142.10 KEP65980.1 - 0.001 18.2 0.8 0.19 10.8 0.2 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.6 KEP65980.1 - 0.0049 15.8 4.6 0.0049 15.8 3.2 1.8 2 0 0 2 2 2 1 UAA transporter family RRM_2 PF04059.7 KEP65981.1 - 6.1e-31 106.2 0.5 1.1e-30 105.4 0.4 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 IQ PF00612.22 KEP65982.1 - 0.0081 15.7 3.8 0.027 14.0 2.6 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF572 PF04502.8 KEP65985.1 - 7.4e-45 153.5 0.0 9.1e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.7 KEP65985.1 - 3.2e-05 23.1 7.4 0.00036 19.7 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding PA26 PF04636.8 KEP65985.1 - 0.039 12.6 0.1 0.054 12.1 0.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Lar_restr_allev PF14354.1 KEP65985.1 - 1.1 9.6 5.0 1.7 8.9 0.3 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 KEP65985.1 - 1.5 8.4 5.9 11 5.6 4.1 2.2 1 1 0 1 1 1 0 zinc-ribbon domain SPX PF03105.14 KEP65986.1 - 2.3e-09 37.4 12.7 2.3e-09 37.4 8.8 4.9 3 1 0 3 3 3 1 SPX domain zf-C3HC4 PF00097.20 KEP65986.1 - 1.7e-05 24.3 9.1 4.4e-05 23.0 6.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP65986.1 - 0.00034 20.5 11.2 0.00034 20.5 7.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RCC1 PF00415.13 KEP65987.1 - 2.4e-50 168.5 7.9 2.9e-08 33.7 0.0 10.4 9 1 0 9 9 9 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP65987.1 - 1.4e-28 97.8 30.0 9e-07 28.3 0.0 8.4 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat MIP-T3 PF10243.4 KEP65987.1 - 0.0011 17.5 40.9 0.0011 17.5 28.4 5.4 3 2 1 5 5 5 2 Microtubule-binding protein MIP-T3 SDA1 PF05285.7 KEP65988.1 - 2 7.6 12.1 1.9 7.6 8.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KEP65988.1 - 2.3 6.0 15.6 2.6 5.8 10.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KEP65988.1 - 3 5.7 10.6 2.5 6.0 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 KEP65988.1 - 8.1 5.0 16.2 9 4.9 11.2 1.0 1 0 0 1 1 1 0 Paf1 Daxx PF03344.10 KEP65988.1 - 8.3 4.7 16.4 8.3 4.7 11.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF663 PF04950.7 KEP65991.1 - 1.5e-69 234.2 0.6 3e-69 233.2 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KEP65991.1 - 9.1e-24 82.8 0.0 2.4e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KEP65991.1 - 2.8e-07 30.1 2.5 3.2e-06 26.6 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 KEP65991.1 - 2.2e-05 24.0 0.1 8.2e-05 22.2 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 KEP65991.1 - 2.4e-05 24.5 0.0 5.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP65991.1 - 0.00011 22.2 0.0 0.00011 22.2 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain MobB PF03205.9 KEP65991.1 - 0.00013 21.7 0.0 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KEP65991.1 - 0.00015 21.6 0.0 0.00072 19.4 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEP65991.1 - 0.00019 22.2 3.5 0.00027 21.7 0.0 3.1 3 0 0 3 3 1 1 AAA domain AAA_22 PF13401.1 KEP65991.1 - 0.00031 20.8 0.0 0.00084 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEP65991.1 - 0.00031 20.6 0.0 0.00077 19.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 KEP65991.1 - 0.00065 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 KEP65991.1 - 0.0024 17.3 0.0 0.0051 16.2 0.0 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KEP65991.1 - 0.0041 17.6 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_5 PF07728.9 KEP65991.1 - 0.0051 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KEP65991.1 - 0.0053 17.0 3.9 0.0055 17.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KEP65991.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KEP65991.1 - 0.006 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KEP65991.1 - 0.0067 16.1 0.1 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.22 KEP65991.1 - 0.0096 16.2 0.5 0.13 12.5 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 KEP65991.1 - 0.013 14.8 0.0 0.047 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KEP65991.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 KEP65991.1 - 0.024 13.6 0.0 0.073 12.0 0.0 1.7 1 0 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.17 KEP65991.1 - 0.024 14.7 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KEP65991.1 - 0.034 13.3 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 KEP65991.1 - 0.038 13.5 0.0 0.038 13.5 0.0 4.4 5 0 0 5 5 5 0 AAA domain SRP54 PF00448.17 KEP65991.1 - 0.043 13.2 2.2 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 KEP65991.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KEP65991.1 - 0.07 12.6 0.0 0.28 10.6 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Hexapep PF00132.19 KEP65992.1 - 0.0002 20.6 1.3 0.91 9.1 0.0 3.3 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Bromo_TP PF07524.8 KEP65993.1 - 0.00039 20.0 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 KEP65993.1 - 0.0033 17.4 1.5 0.0033 17.4 1.0 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term CEP44 PF15007.1 KEP65994.1 - 2.7e-31 108.0 0.0 5e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 LDB19 PF13002.2 KEP65994.1 - 0.088 12.2 0.2 0.22 10.9 0.2 1.6 1 1 0 1 1 1 0 Arrestin_N terminal like GP41 PF00517.12 KEP65994.1 - 0.48 9.9 0.6 1.1 8.8 0.4 1.5 1 0 0 1 1 1 0 Retroviral envelope protein DUF2330 PF10092.4 KEP65997.1 - 0.069 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) zf-C3HC4_3 PF13920.1 KEP65998.1 - 1.4e-08 34.2 9.4 8.4e-07 28.5 3.3 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP65998.1 - 0.00015 21.7 4.0 0.00015 21.7 2.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP65998.1 - 0.0011 18.6 3.7 0.0011 18.6 2.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) YjbE PF11106.3 KEP65999.1 - 0.21 11.6 0.1 0.21 11.6 0.1 3.2 3 0 0 3 3 3 0 Exopolysaccharide production protein YjbE zf-CCCH PF00642.19 KEP66000.1 - 4.6e-08 32.5 19.8 1.5e-05 24.5 4.7 3.3 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEP66000.1 - 0.00024 20.9 8.7 0.0067 16.3 3.7 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type RRM_6 PF14259.1 KEP66001.1 - 0.00018 21.4 0.0 0.00055 19.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3349 PF11829.3 KEP66001.1 - 0.029 14.8 0.1 0.11 12.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) RRM_1 PF00076.17 KEP66001.1 - 0.038 13.6 0.0 0.12 11.9 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66001.1 - 0.17 11.7 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad51 PF08423.6 KEP66002.1 - 0.0033 16.3 0.1 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 Rad51 Sel1 PF08238.7 KEP66004.1 - 1.3e-12 47.9 39.6 4.4e-05 23.9 0.1 11.2 13 0 0 13 13 13 7 Sel1 repeat DUF202 PF02656.10 KEP66005.1 - 0.58 10.4 0.0 0.58 10.4 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF202) oligo_HPY PF08352.7 KEP66006.1 - 0.26 11.6 0.1 0.26 11.6 0.1 1.7 2 1 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Adaptin_N PF01602.15 KEP66007.1 - 3.6e-122 408.3 0.0 4.2e-122 408.1 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KEP66007.1 - 1.1e-18 67.6 0.0 2.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KEP66007.1 - 1.7e-08 34.5 0.3 0.042 14.1 0.0 4.5 3 2 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KEP66007.1 - 0.001 18.9 1.0 0.2 11.5 0.5 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KEP66007.1 - 0.044 13.6 0.5 56 3.7 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 KEP66007.1 - 0.097 12.2 0.2 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) zf-C2HC_2 PF13913.1 KEP66008.1 - 0.00018 21.0 10.6 0.0019 17.8 0.7 3.4 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-TRAF PF02176.13 KEP66008.1 - 0.02 15.2 2.5 0.02 15.2 1.8 1.8 2 0 0 2 2 2 0 TRAF-type zinc finger Chorein_N PF12624.2 KEP66012.1 - 2.3e-22 78.7 0.7 3.9e-22 78.0 0.5 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 KEP66012.1 - 3.2e-14 52.8 0.0 3.9e-06 26.2 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Dicty_CAD PF05720.7 KEP66012.1 - 2.1 8.0 0.0 5.2 6.7 0.0 1.6 1 0 0 1 1 1 0 Cell-cell adhesion domain DUF3104 PF11302.3 KEP66012.1 - 9.4 5.6 0.0 20 4.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DDHD PF02862.12 KEP66013.1 - 2.8e-25 89.4 11.6 4.5e-17 62.6 0.0 6.2 5 2 0 5 5 5 2 DDHD domain DUF676 PF05057.9 KEP66013.1 - 0.059 12.6 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DLH PF01738.13 KEP66013.1 - 0.085 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.20 KEP66013.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FPL PF09758.4 KEP66014.1 - 3.6e-50 169.5 3.5 5.1e-50 169.1 2.4 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein MMS19_C PF12460.3 KEP66014.1 - 0.32 9.6 0.2 0.54 8.9 0.1 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Cyt-b5 PF00173.23 KEP66015.1 - 3.7e-19 68.3 0.0 6.2e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RCC1 PF00415.13 KEP66016.1 - 1.4e-35 121.2 14.0 2.7e-12 46.6 0.0 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEP66016.1 - 3.4e-32 109.3 20.9 3.3e-09 36.1 0.8 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.10 KEP66016.1 - 0.059 13.1 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Ribosomal_L7Ae PF01248.21 KEP66017.1 - 5.5e-19 67.4 0.1 1.4e-18 66.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L22 PF00237.14 KEP66018.1 - 2.2e-23 82.2 0.2 3.5e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e zf-C4H2 PF10146.4 KEP66020.1 - 0.88 9.5 6.9 0.5 10.3 3.5 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein FRG2 PF15315.1 KEP66021.1 - 1 9.2 15.0 1.2 9.0 10.4 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Pox_Ag35 PF03286.9 KEP66022.1 - 1.5 8.3 7.7 2 7.8 5.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.8 KEP66022.1 - 9.3 4.8 9.3 11 4.6 6.5 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 KEP66022.1 - 9.9 3.9 23.4 12 3.6 16.3 1.0 1 0 0 1 1 1 0 Nop14-like family SAM_decarbox PF01536.11 KEP66023.1 - 1.1 7.9 0.0 1.7 7.2 0.0 1.2 1 0 0 1 1 1 0 Adenosylmethionine decarboxylase Fez1 PF06818.10 KEP66024.1 - 0.00023 21.2 22.4 0.00023 21.2 15.6 6.6 4 2 2 6 6 6 1 Fez1 LMSTEN PF07988.7 KEP66024.1 - 0.019 14.2 3.8 0.025 13.8 1.1 2.5 2 0 0 2 2 2 0 LMSTEN motif HSBP1 PF06825.7 KEP66024.1 - 0.29 10.7 6.4 0.17 11.4 0.7 2.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 HhH-GPD PF00730.20 KEP66025.1 - 3.5e-17 62.6 0.0 8.1e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KEP66025.1 - 6e-08 32.1 1.0 0.007 15.7 0.1 2.8 2 0 0 2 2 2 2 NUDIX domain HHH PF00633.18 KEP66025.1 - 1.8e-05 24.1 0.5 4e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 KEP66025.1 - 6.6 7.0 17.1 0.052 13.7 4.6 3.1 2 1 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Clat_adaptor_s PF01217.15 KEP66026.1 - 3.8e-42 143.3 0.2 4.1e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Nucleoporin_FG PF13634.1 KEP66029.1 - 1e-06 28.9 227.2 0.0001 22.4 29.1 7.7 2 1 5 7 7 7 3 Nucleoporin FG repeat region vWA-TerF-like PF10138.4 KEP66029.1 - 6.2 6.5 0.0 9.9 5.9 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus AAA_33 PF13671.1 KEP66030.1 - 4.6e-09 36.2 0.7 0.00059 19.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain KTI12 PF08433.5 KEP66030.1 - 5.4e-06 25.8 0.0 0.098 11.8 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_18 PF13238.1 KEP66030.1 - 4.4e-05 23.7 0.0 0.003 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEP66030.1 - 5.2e-05 24.0 0.0 0.00049 20.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEP66030.1 - 0.0057 16.6 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KEP66030.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP66030.1 - 0.084 13.0 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain PC_rep PF01851.17 KEP66031.1 - 9.8e-16 57.0 23.9 0.00038 20.5 0.2 9.6 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KEP66031.1 - 0.0077 16.4 5.0 1.1 9.5 0.1 4.1 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 KEP66031.1 - 0.01 15.8 0.1 5.3 7.3 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat DUF2201_N PF13203.1 KEP66031.1 - 3.2 6.8 16.3 0.015 14.4 4.8 1.8 2 0 0 2 2 2 0 Putative metallopeptidase domain DnaJ PF00226.26 KEP66032.1 - 4.9e-29 99.8 1.4 7.4e-29 99.2 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L6e PF01159.14 KEP66033.1 - 3.7e-35 120.4 0.9 5.7e-35 119.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e AUX_IAA PF02309.11 KEP66035.1 - 0.0041 16.8 1.8 0.53 10.0 0.0 2.2 2 0 0 2 2 2 2 AUX/IAA family EF-hand_7 PF13499.1 KEP66035.1 - 0.047 13.8 0.0 1.1 9.4 0.0 2.8 2 2 0 2 2 2 0 EF-hand domain pair Cauli_AT PF03233.8 KEP66035.1 - 0.049 13.3 3.1 0.069 12.8 2.1 1.2 1 0 0 1 1 1 0 Aphid transmission protein TcdA_TcdB PF12919.2 KEP66035.1 - 0.8 8.1 6.0 0.45 8.9 3.1 1.4 1 1 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain LRR_6 PF13516.1 KEP66036.1 - 7.2e-07 28.6 0.8 0.32 11.1 0.0 4.7 4 0 0 4 4 4 3 Leucine Rich repeat WD40 PF00400.27 KEP66038.1 - 6.2e-06 25.8 0.3 1.3 9.0 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat PD40 PF07676.7 KEP66038.1 - 0.13 12.0 4.7 19 5.0 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SGL PF08450.7 KEP66038.1 - 0.14 11.5 0.0 5.9 6.1 0.0 3.0 1 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Pkinase PF00069.20 KEP66040.1 - 2.9e-22 79.0 0.0 7.8e-22 77.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KEP66040.1 - 1.1e-18 67.2 0.0 4.6e-18 65.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KEP66040.1 - 2.4e-11 43.1 0.0 1e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase BTK PF00779.14 KEP66041.1 - 0.0097 15.5 1.2 0.019 14.6 0.9 1.4 1 0 0 1 1 1 1 BTK motif DnaJ-X PF14308.1 KEP66042.1 - 2e-63 213.4 1.7 3.7e-63 212.5 1.2 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 KEP66042.1 - 3.3e-27 94.0 1.8 7.7e-27 92.8 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain Ndc1_Nup PF09531.5 KEP66042.1 - 1.3 7.3 3.3 2.3 6.5 2.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YL1 PF05764.8 KEP66044.1 - 1.2e-24 87.2 37.1 1.2e-24 87.2 25.7 3.6 3 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 KEP66044.1 - 5.4e-12 45.0 0.2 1e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MORN PF02493.15 KEP66045.1 - 3.3e-39 130.3 57.3 3.8e-08 32.5 2.2 9.8 10 0 0 10 10 10 7 MORN repeat TFIIIC_sub6 PF10419.4 KEP66045.1 - 1.2 8.6 10.6 12 5.4 0.1 5.4 6 0 0 6 6 6 0 TFIIIC subunit WD40 PF00400.27 KEP66046.1 - 3.4e-46 153.5 35.9 5.9e-10 38.6 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat Nbas_N PF15492.1 KEP66046.1 - 0.15 11.1 0.6 4.3 6.3 0.0 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DEAD PF00270.24 KEP66048.1 - 2.5e-40 137.7 0.0 1.7e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP66048.1 - 3.4e-29 100.5 0.3 7.2e-29 99.4 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KEP66048.1 - 0.0026 17.7 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 KEP66048.1 - 0.0064 14.9 0.0 0.023 13.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) ResIII PF04851.10 KEP66048.1 - 0.012 15.4 0.0 0.07 12.9 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit EIF_2_alpha PF07541.7 KEP66050.1 - 2.6e-36 123.7 0.0 5.1e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KEP66050.1 - 5.2e-11 42.4 0.2 1.3e-10 41.2 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain FSIP1 PF15554.1 KEP66050.1 - 9.3e-05 21.4 4.4 0.00015 20.7 3.0 1.3 1 0 0 1 1 1 1 FSIP1 family MOZART2 PF12926.2 KEP66050.1 - 0.0073 15.8 0.1 0.86 9.2 0.0 2.4 2 0 0 2 2 2 1 Mitotic-spindle organizing gamma-tubulin ring associated EXOSC1 PF10447.4 KEP66050.1 - 0.053 13.4 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 RNA_pol_3_Rpc31 PF11705.3 KEP66050.1 - 0.092 12.6 14.7 0.17 11.8 10.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mob1_phocein PF03637.12 KEP66051.1 - 4.8e-21 75.2 3.9 3.9e-13 49.4 2.0 3.2 3 0 0 3 3 3 3 Mob1/phocein family MarC PF01914.12 KEP66052.1 - 4 6.5 0.0 10 5.1 0.0 1.6 1 0 0 1 1 1 0 MarC family integral membrane protein F-box-like_2 PF13013.1 KEP66053.1 - 1.5e-17 63.3 0.5 5.3e-17 61.5 0.3 2.0 1 0 0 1 1 1 1 F-box-like domain LRR_4 PF12799.2 KEP66053.1 - 4.3e-07 29.3 0.1 0.021 14.4 0.0 5.5 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) ELL PF10390.4 KEP66053.1 - 0.0079 15.4 4.8 0.0079 15.4 3.3 2.5 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL LRR_7 PF13504.1 KEP66053.1 - 0.95 9.9 10.0 83 4.0 0.0 7.1 8 0 0 8 8 8 0 Leucine rich repeat Ras PF00071.17 KEP66054.1 - 2.6e-57 192.7 0.4 3e-57 192.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KEP66054.1 - 1.2e-20 73.4 0.1 1.6e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KEP66054.1 - 1e-17 64.6 0.0 1.4e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KEP66054.1 - 1.7e-09 37.2 0.1 2e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEP66054.1 - 6e-05 22.5 0.0 9.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEP66054.1 - 6.3e-05 22.9 0.0 0.0002 21.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KEP66054.1 - 0.00062 19.7 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 KEP66054.1 - 0.001 18.3 0.1 0.0023 17.2 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 KEP66054.1 - 0.0078 15.7 0.3 0.028 13.9 0.0 2.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_5 PF07728.9 KEP66054.1 - 0.0087 15.7 0.1 0.025 14.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KEP66054.1 - 0.017 14.3 0.3 0.063 12.4 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEP66054.1 - 0.022 14.9 0.0 0.041 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KEP66054.1 - 0.024 14.2 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain CbiA PF01656.18 KEP66054.1 - 0.068 12.5 0.0 8.8 5.6 0.0 2.1 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_15 PF13175.1 KEP66054.1 - 0.071 12.1 0.0 0.082 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 KEP66054.1 - 0.084 11.7 0.2 0.21 10.4 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KEP66054.1 - 0.12 12.5 0.1 0.48 10.6 0.1 1.9 1 1 0 1 1 1 0 RNA helicase Pkinase PF00069.20 KEP66055.1 - 4e-53 180.2 0.0 8.7e-53 179.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66055.1 - 1.2e-24 86.7 0.1 5.3e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 KEP66055.1 - 0.00031 20.1 0.1 0.0016 17.8 0.0 2.1 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 KEP66055.1 - 0.1 11.3 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cmc1 PF08583.5 KEP66056.1 - 0.0023 17.6 0.2 0.0042 16.8 0.2 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Rab3-GTPase_cat PF13890.1 KEP66057.1 - 0.1 11.9 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Iso_dh PF00180.15 KEP66058.1 - 1.2e-70 238.1 0.0 1.7e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF89 PF01937.14 KEP66058.1 - 3.4e-64 216.8 0.0 5e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF1155 PF06633.6 KEP66058.1 - 0.0023 17.1 0.0 0.0054 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1155) DUF4458 PF14660.1 KEP66058.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) Nop14 PF04147.7 KEP66059.1 - 1.3e-50 172.2 82.8 9e-40 136.3 33.4 4.3 3 1 1 4 4 4 4 Nop14-like family DUF2636 PF11120.3 KEP66059.1 - 0.12 11.8 0.1 0.42 10.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) RNA_pol_A_bac PF01000.21 KEP66060.1 - 2.1e-08 34.2 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain HHH_5 PF14520.1 KEP66060.1 - 2.2e-07 30.9 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_L PF01193.19 KEP66060.1 - 6.2e-05 22.0 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_CTD PF03118.10 KEP66060.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain SRP54 PF00448.17 KEP66063.1 - 5.6e-79 264.1 0.1 1.3e-78 262.9 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KEP66063.1 - 9.9e-28 96.4 2.3 9.9e-28 96.4 1.6 3.1 3 1 0 3 3 1 1 Signal peptide binding domain SRP54_N PF02881.14 KEP66063.1 - 2.5e-08 33.9 0.0 1.8e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 KEP66063.1 - 3e-08 33.6 0.2 9.5e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEP66063.1 - 9.3e-07 28.4 0.2 4e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KEP66063.1 - 1.5e-06 27.9 0.0 4.3e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KEP66063.1 - 3.1e-06 26.7 0.0 1.1e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KEP66063.1 - 8.5e-05 22.5 0.7 0.54 10.1 0.0 3.4 4 1 0 4 4 4 2 AAA domain ArgK PF03308.11 KEP66063.1 - 0.00015 20.6 0.8 0.0084 14.9 0.0 2.9 3 0 0 3 3 3 1 ArgK protein AAA_22 PF13401.1 KEP66063.1 - 0.00074 19.6 0.0 0.0031 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEP66063.1 - 0.00085 20.1 0.0 0.0016 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEP66063.1 - 0.0011 18.0 0.2 0.0027 16.8 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 KEP66063.1 - 0.0019 17.8 0.0 0.0061 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP66063.1 - 0.0057 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 KEP66063.1 - 0.0074 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.5 KEP66063.1 - 0.011 15.0 0.3 7.6 5.7 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF2209 PF09974.4 KEP66063.1 - 0.032 14.3 0.7 0.15 12.1 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) ATP_bind_1 PF03029.12 KEP66063.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KEP66063.1 - 0.053 13.8 0.2 0.31 11.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEP66063.1 - 0.065 12.6 0.0 0.18 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.6 KEP66063.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein Exonuc_VII_L PF02601.10 KEP66064.1 - 0.012 14.8 10.5 0.017 14.3 7.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.7 KEP66064.1 - 0.025 14.3 9.1 0.25 11.1 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KEP66064.1 - 0.097 11.8 1.2 0.25 10.4 0.7 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Peptidase_M13_N PF05649.8 KEP66064.1 - 0.71 8.8 7.9 14 4.5 5.5 2.0 1 1 0 1 1 1 0 Peptidase family M13 Spc7 PF08317.6 KEP66064.1 - 0.79 8.3 17.3 0.24 10.0 9.9 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 KEP66064.1 - 1.6 8.6 19.0 2 8.2 6.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mit_KHE1 PF10173.4 KEP66064.1 - 5.3 6.8 8.9 5.6 6.7 1.6 2.2 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related IF-2B PF01008.12 KEP66066.1 - 8.1e-48 162.8 0.0 1e-46 159.2 0.0 2.1 1 1 0 1 1 1 1 Initiation factor 2 subunit family adh_short PF00106.20 KEP66067.1 - 7.7e-17 61.7 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEP66067.1 - 1.6e-05 24.7 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEP66067.1 - 0.0029 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Scs3p PF10261.4 KEP66069.1 - 1.6e-07 30.5 0.0 2.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM JSRP PF15312.1 KEP66069.1 - 0.12 12.3 0.0 0.12 12.3 0.0 4.4 4 0 0 4 4 4 0 Junctional sarcoplasmic reticulum protein Sulfate_transp PF00916.15 KEP66071.1 - 5.3e-54 183.1 5.8 2.4e-53 180.9 4.0 1.9 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEP66071.1 - 8e-23 79.9 1.7 8e-23 79.9 1.2 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEP66071.1 - 3.1e-21 74.9 0.0 5.6e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain DEAD PF00270.24 KEP66072.1 - 7e-40 136.2 0.0 9.7e-40 135.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP66072.1 - 1.6e-26 91.9 0.1 3.2e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KEP66072.1 - 0.05 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 KEP66072.1 - 0.095 12.5 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.24 KEP66074.1 - 3.4e-43 147.0 0.1 7e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KEP66074.1 - 1.2e-21 76.0 0.4 2.2e-21 75.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KEP66074.1 - 6.7e-21 73.9 0.0 1.9e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain eIF2_C PF09173.6 KEP66074.1 - 0.12 12.3 0.1 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Initiation factor eIF2 gamma, C terminal Pox_Ag35 PF03286.9 KEP66074.1 - 1.6 8.2 8.6 2.6 7.5 5.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Trichoplein PF13868.1 KEP66075.1 - 3.9e-49 166.9 148.6 3.9e-49 166.9 103.0 2.0 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin Acetyltransf_9 PF13527.1 KEP66077.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nop16 PF09420.5 KEP66078.1 - 2.1e-12 47.4 0.0 2.1e-12 47.4 0.0 3.1 2 1 1 3 3 3 2 Ribosome biogenesis protein Nop16 DUF1178 PF06676.6 KEP66078.1 - 0.25 11.5 6.4 0.062 13.5 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Cnl2_NKP2 PF09447.5 KEP66078.1 - 0.78 9.4 4.6 2.9 7.6 0.2 2.5 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Cys_Met_Meta_PP PF01053.15 KEP66081.1 - 1e-123 412.5 0.0 1.1e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KEP66081.1 - 5.2e-09 35.5 0.1 7.1e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEP66081.1 - 3e-07 29.5 0.0 4.1e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEP66081.1 - 8.4e-07 28.3 0.0 3e-06 26.5 0.0 1.7 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KEP66081.1 - 0.00024 20.3 0.0 0.00058 19.0 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 KEP66081.1 - 0.0024 16.3 0.0 0.0035 15.8 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) MobB PF03205.9 KEP66082.1 - 4.2e-06 26.5 0.0 8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PA PF02225.17 KEP66084.1 - 3.1e-08 33.2 0.1 5.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 PA domain VID27 PF08553.5 KEP66085.1 - 0.22 9.7 1.8 0.41 8.7 1.2 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC27 PF09507.5 KEP66087.1 - 0.00011 21.5 18.4 0.00022 20.5 12.8 1.5 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Abhydrolase_5 PF12695.2 KEP66088.1 - 1.8e-07 30.9 0.0 5.2e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family GLTSCR1 PF15249.1 KEP66088.1 - 0.0015 18.6 0.1 0.03 14.4 0.0 2.9 2 0 0 2 2 2 1 Glioma tumor suppressor candidate region DUF818 PF05677.7 KEP66088.1 - 6.5 5.3 0.0 11 4.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) ETRAMP PF09716.5 KEP66089.1 - 0.54 10.2 6.8 0.19 11.7 0.2 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MRP-L27 PF09809.4 KEP66090.1 - 1.4e-11 43.9 0.0 1.7e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Abhydrolase_6 PF12697.2 KEP66092.1 - 6.1e-20 72.0 4.6 1.5e-19 70.8 3.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP66092.1 - 1.6e-10 40.8 0.1 8.3e-10 38.5 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP66092.1 - 1.3e-07 31.3 0.2 2.9e-05 23.7 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PUB PF09409.5 KEP66094.1 - 3e-05 23.6 0.0 6.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 PUB domain zinc_ribbon_5 PF13719.1 KEP66097.1 - 0.071 12.7 0.6 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KEP66097.1 - 0.09 12.4 0.8 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain CsgE PF10627.4 KEP66097.1 - 0.18 11.6 0.5 1 9.2 0.0 2.2 3 0 0 3 3 3 0 Curli assembly protein CsgE PSD4 PF07631.6 KEP66098.1 - 0.052 13.9 0.1 15 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) Ribosomal_L27 PF01016.14 KEP66099.1 - 1.6e-07 30.9 0.1 0.00051 19.7 0.0 2.2 1 1 1 2 2 2 2 Ribosomal L27 protein DUF4577 PF15145.1 KEP66100.1 - 0.081 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) 14-3-3 PF00244.15 KEP66101.1 - 6.4e-110 365.8 13.0 7.8e-110 365.5 9.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 KEP66101.1 - 0.0073 15.6 2.8 0.0073 15.6 1.9 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF4085) Uteroglobin PF01099.12 KEP66101.1 - 0.074 12.8 2.5 6.3 6.6 0.5 2.8 2 0 0 2 2 2 0 Uteroglobin family DUF3106 PF11304.3 KEP66101.1 - 4.8 7.6 10.3 20 5.6 4.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) zf-C3HC PF07967.8 KEP66102.1 - 5.4e-06 26.1 0.5 3.7e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 C3HC zinc finger-like Pkinase PF00069.20 KEP66104.1 - 3e-54 183.9 0.1 3.7e-52 177.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66104.1 - 2.4e-17 62.8 0.0 5.2e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEP66104.1 - 1.8e-06 27.8 0.0 5e-05 23.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEP66104.1 - 0.0071 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase_B_N PF11791.3 KEP66104.1 - 0.022 14.5 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Aconitate B N-terminal domain Choline_kinase PF01633.15 KEP66104.1 - 0.035 13.6 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KEP66104.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family PC_rep PF01851.17 KEP66105.1 - 2.6e-31 106.0 29.0 6.7e-07 29.2 0.0 10.1 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KEP66105.1 - 1.1e-12 48.0 9.9 1.3e-06 28.5 0.0 4.8 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 KEP66105.1 - 4e-07 29.5 0.8 3 8.1 0.1 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KEP66105.1 - 6.8e-07 29.5 9.9 0.00011 22.5 0.0 5.7 5 0 0 5 5 5 2 HEAT-like repeat HEAT_PBS PF03130.11 KEP66105.1 - 2 9.1 10.2 32 5.3 0.1 5.5 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Ribosomal_L13e PF01294.13 KEP66106.1 - 1.2e-59 200.7 3.8 1.6e-59 200.3 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.14 KEP66107.1 - 1.2e-35 122.3 0.2 1.5e-35 122.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Dynein_light PF01221.13 KEP66108.1 - 4.8e-28 96.9 0.3 5.2e-28 96.8 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ribosomal_L33 PF00471.15 KEP66109.1 - 6.6e-20 71.0 1.2 7.9e-20 70.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 BTB PF00651.26 KEP66110.1 - 9e-09 35.3 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pox_VERT_large PF04441.8 KEP66110.1 - 0.075 11.1 0.0 0.1 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit Beach PF02138.13 KEP66111.1 - 9.3e-62 208.9 0.0 8.4e-40 136.9 0.0 2.3 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.27 KEP66111.1 - 8e-11 41.3 1.3 7.9e-05 22.3 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat PH_BEACH PF14844.1 KEP66111.1 - 0.48 10.2 0.0 4.6 7.1 0.0 2.5 2 1 0 2 2 2 0 PH domain associated with Beige/BEACH CBM_20 PF00686.14 KEP66112.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Starch binding domain Y2_Tnp PF04986.8 KEP66113.1 - 1.2 8.9 5.1 3.1 7.5 3.5 1.7 1 1 0 1 1 1 0 Putative transposase zf-CCCH PF00642.19 KEP66114.1 - 8.5 6.1 24.7 2 8.1 2.3 4.5 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LUC7 PF03194.10 KEP66115.1 - 4.4e-48 164.0 1.1 4.4e-48 164.0 0.8 2.0 2 0 0 2 2 2 1 LUC7 N_terminus Dsh_C PF12316.3 KEP66115.1 - 0.074 13.1 12.7 0.12 12.4 8.8 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Zip PF02535.17 KEP66115.1 - 0.83 8.5 4.9 1.2 8.0 3.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 KEP66115.1 - 1.5 6.9 12.2 2 6.5 8.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp PF00026.18 KEP66117.1 - 1.8e-75 254.1 0.0 2.5e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEP66117.1 - 2.8e-08 33.9 0.0 3.9e-07 30.1 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KEP66117.1 - 1.7e-06 27.7 0.0 1.2e-05 24.9 0.0 2.2 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Phage_GPD PF05954.6 KEP66117.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) DPM3 PF08285.6 KEP66120.1 - 1.4e-14 53.7 0.4 2.8e-12 46.3 0.0 2.0 2 0 0 2 2 2 2 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) NapE PF06796.6 KEP66120.1 - 0.028 13.7 0.5 0.028 13.7 0.3 1.6 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Trypsin_2 PF13365.1 KEP66121.1 - 1.6e-15 57.1 0.5 4.2e-15 55.8 0.4 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 KEP66121.1 - 6.9e-12 45.4 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 KEP66121.1 - 6.8e-06 25.8 0.2 6.6e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 PDZ domain Ski_Sno PF02437.12 KEP66121.1 - 0.035 13.6 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 SKI/SNO/DAC family NAD_binding_1 PF00175.16 KEP66122.1 - 2.6e-26 92.2 0.0 4.8e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEP66122.1 - 2.2e-21 75.8 0.0 6.3e-19 67.9 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.6 KEP66122.1 - 3.1e-07 30.3 0.0 1.1e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.7 KEP66122.1 - 6e-05 23.0 0.0 0.0022 17.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain TctA PF01970.11 KEP66123.1 - 1.8 6.8 0.0 2.8 6.2 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family HATPase_c PF02518.21 KEP66124.1 - 0.036 13.7 0.0 0.68 9.6 0.0 2.3 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2464 PF10240.4 KEP66125.1 - 0.31 10.3 2.9 0.8 8.9 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) Arf PF00025.16 KEP66126.1 - 8.2e-75 249.8 0.0 9.5e-75 249.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEP66126.1 - 3.6e-13 49.2 0.0 4.2e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KEP66126.1 - 1.8e-12 46.6 0.0 9.1e-09 34.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KEP66126.1 - 1.6e-10 40.5 0.0 2.2e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KEP66126.1 - 3.8e-10 39.3 0.0 4.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEP66126.1 - 5.1e-09 36.6 0.0 6.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEP66126.1 - 1.4e-06 28.2 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 KEP66126.1 - 0.0013 17.5 0.0 0.028 13.2 0.0 2.5 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 KEP66126.1 - 0.0038 16.5 0.3 0.027 13.7 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEP66126.1 - 0.0083 15.5 0.0 0.53 9.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 KEP66126.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain SPRY PF00622.23 KEP66127.1 - 0.0018 18.3 0.2 16 5.6 0.1 4.1 4 0 0 4 4 4 2 SPRY domain Peptidase_C50 PF03568.12 KEP66128.1 - 1.9e-26 92.6 0.0 6.4e-15 54.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase family C50 DUF212 PF02681.9 KEP66128.1 - 1.2 8.8 4.5 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Divergent PAP2 family DNA_pol_phi PF04931.8 KEP66128.1 - 8.2 4.0 16.6 25 2.4 11.5 1.8 1 0 0 1 1 1 0 DNA polymerase phi Frataxin_Cyay PF01491.11 KEP66129.1 - 2.2e-20 72.4 0.0 2.9e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain LRR_6 PF13516.1 KEP66130.1 - 9.7e-08 31.3 8.4 0.00064 19.5 0.3 3.5 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.2 KEP66130.1 - 0.00022 20.7 5.1 0.0053 16.3 2.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEP66130.1 - 0.0032 17.2 5.8 3.8 7.9 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 KEP66130.1 - 0.014 15.4 8.7 5.3 7.7 0.1 4.1 3 1 0 3 3 3 0 Leucine rich repeat FHA PF00498.21 KEP66131.1 - 2e-09 37.4 0.0 4.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain PARG_cat PF05028.9 KEP66132.1 - 5.2e-52 177.1 0.0 6.2e-25 88.1 0.0 3.4 3 1 0 3 3 3 3 Poly (ADP-ribose) glycohydrolase (PARG) SET PF00856.23 KEP66133.1 - 2.2e-06 28.0 0.0 6.5e-06 26.5 0.0 1.8 2 1 0 2 2 2 1 SET domain zf-rbx1 PF12678.2 KEP66134.1 - 3.5e-08 33.4 2.9 3.5e-08 33.4 2.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KEP66134.1 - 1.1e-06 28.3 3.5 1.1e-06 28.3 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 KEP66134.1 - 3e-05 23.7 1.2 8.6e-05 22.3 0.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KEP66134.1 - 0.013 15.1 1.5 0.042 13.5 1.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP66134.1 - 0.068 12.8 6.5 0.02 14.5 1.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KEP66134.1 - 0.4 10.3 11.6 0.043 13.4 4.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 KEP66135.1 - 1e-13 51.0 0.0 1.3e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66135.1 - 7.5e-08 31.7 0.0 4.5e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP66135.1 - 8.4e-07 28.2 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEP66135.1 - 0.0039 16.9 0.2 0.02 14.6 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family eIF-1a PF01176.14 KEP66136.1 - 1e-28 98.5 0.3 1.5e-28 97.9 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ctr PF04145.10 KEP66137.1 - 7.2e-30 103.9 2.9 1.8e-29 102.6 2.0 1.7 1 0 0 1 1 1 1 Ctr copper transporter family TPR_11 PF13414.1 KEP66138.1 - 2e-09 36.9 3.1 5.3e-09 35.6 2.1 1.8 1 0 0 1 1 1 1 TPR repeat TPR_9 PF13371.1 KEP66138.1 - 1.4e-07 31.2 2.1 1.4e-07 31.2 1.5 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEP66138.1 - 1.6e-06 27.4 2.3 0.026 14.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP66138.1 - 0.00014 21.5 8.2 0.06 13.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEP66138.1 - 0.014 16.0 5.7 0.014 16.0 3.9 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP66138.1 - 0.017 15.6 5.2 0.76 10.5 0.2 3.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.13 KEP66139.1 - 1.1e-26 92.6 7.7 1.5e-26 92.3 5.4 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KEP66139.1 - 0.00024 20.6 3.0 0.00024 20.6 2.1 1.8 2 0 0 2 2 2 1 KOW motif Rgp1 PF08737.5 KEP66140.1 - 3e-12 46.3 0.5 0.00019 20.6 0.0 3.2 3 0 0 3 3 3 2 Rgp1 Arrestin_N PF00339.24 KEP66140.1 - 0.0022 17.8 0.4 0.34 10.7 0.2 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Ribosomal_L18ae PF01775.12 KEP66141.1 - 1.6e-55 186.3 0.4 2e-55 186.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain TRCF PF03461.10 KEP66141.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 TRCF domain WD40 PF00400.27 KEP66143.1 - 3e-15 55.4 2.6 8.3e-06 25.4 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2673 PF10880.3 KEP66143.1 - 0.27 11.3 0.2 0.63 10.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) COX4 PF02936.9 KEP66144.1 - 0.00036 20.2 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV RRM_1 PF00076.17 KEP66146.1 - 1.2e-40 136.9 0.0 1.3e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66146.1 - 1.5e-30 104.9 0.0 9.2e-17 60.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66146.1 - 4.2e-12 45.7 0.0 1.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEP66146.1 - 0.00014 21.6 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 KEP66146.1 - 0.0011 18.6 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 ERAP1_C PF11838.3 KEP66149.1 - 0.008 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain PPP4R2 PF09184.6 KEP66150.1 - 0.29 10.6 7.0 0.34 10.4 4.8 1.1 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.11 KEP66150.1 - 0.42 9.5 4.0 0.59 9.0 2.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 KEP66150.1 - 2 6.3 9.6 2 6.3 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KEP66150.1 - 3.1 5.6 15.3 3.2 5.5 10.6 1.0 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 KEP66150.1 - 3.8 6.5 6.0 4.4 6.3 4.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nucleo_P87 PF07267.6 KEP66150.1 - 5 5.6 5.3 5.3 5.6 3.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SDA1 PF05285.7 KEP66150.1 - 5.1 6.2 14.2 5.8 6.1 9.8 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_M1 PF01433.15 KEP66151.1 - 0.059 12.4 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M1 Peptidase_M1 PF01433.15 KEP66152.1 - 1.3e-07 31.1 0.0 1.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 Toxin_30 PF08117.6 KEP66154.1 - 7.6 6.6 13.5 31 4.7 2.9 2.8 1 1 1 2 2 2 0 Ptu family Pkinase PF00069.20 KEP66155.1 - 1.1e-48 165.6 0.0 3.3e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66155.1 - 1.1e-19 70.5 0.0 8.2e-10 38.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP66155.1 - 0.002 17.1 0.1 0.88 8.4 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KEP66155.1 - 0.15 11.0 0.1 0.39 9.7 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.1 KEP66156.1 - 2.2e-10 39.5 9.7 0.4 10.9 0.0 7.8 8 1 1 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.2 KEP66156.1 - 1.9e-07 30.5 2.5 0.0025 17.3 0.1 5.5 5 1 2 7 7 7 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP66156.1 - 1.2e-05 24.9 2.7 0.032 13.9 0.1 4.2 3 1 0 3 3 3 2 Leucine rich repeat F-box PF00646.28 KEP66156.1 - 1.4e-05 24.5 0.3 1.4e-05 24.5 0.2 3.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KEP66156.1 - 3.7e-05 23.3 0.6 3.7e-05 23.3 0.4 2.8 2 0 0 2 2 2 1 F-box-like DUF2217 PF10265.4 KEP66156.1 - 3 6.4 6.2 0.17 10.5 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) MIP-T3 PF10243.4 KEP66156.1 - 7.8 4.8 22.9 15 3.9 15.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Paf1 PF03985.8 KEP66156.1 - 8.7 4.9 9.8 14 4.2 6.8 1.3 1 0 0 1 1 1 0 Paf1 Pro_isomerase PF00160.16 KEP66157.1 - 9e-28 97.4 0.0 1.2e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MMR_HSR1 PF01926.18 KEP66158.1 - 6.1e-17 61.6 0.0 1.6e-16 60.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP66158.1 - 4.1e-05 23.0 0.0 0.033 13.6 0.0 2.8 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEP66158.1 - 0.0069 15.5 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KEP66158.1 - 0.017 14.4 0.0 0.083 12.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 KEP66158.1 - 0.031 14.5 0.0 0.093 13.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 KEP66158.1 - 0.05 12.3 0.1 0.22 10.2 0.1 2.0 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 KEP66158.1 - 0.18 12.3 0.0 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 KEP66158.1 - 0.23 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KEP66158.1 - 0.42 10.4 2.1 0.67 9.7 0.0 2.4 3 0 0 3 3 3 0 Dynamin family Abhydrolase_5 PF12695.2 KEP66159.1 - 1.9e-23 82.8 0.0 2.4e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP66159.1 - 1e-09 38.5 0.7 6.3e-05 22.9 0.0 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP66159.1 - 8.9e-08 31.9 0.2 0.00074 19.1 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.7 KEP66159.1 - 1.5e-06 27.1 0.1 2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 KEP66159.1 - 5.9e-05 22.6 0.2 0.00039 19.9 0.1 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.9 KEP66159.1 - 6.2e-05 22.3 0.2 0.022 13.9 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 KEP66159.1 - 0.0022 17.2 0.0 0.012 14.8 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 KEP66159.1 - 0.006 16.0 0.0 0.0087 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 KEP66159.1 - 0.037 13.8 0.2 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Peptidase_S15 PF02129.13 KEP66159.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.6 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Robl_LC7 PF03259.12 KEP66160.1 - 2.7e-27 94.1 0.0 3e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain MAPKK1_Int PF08923.5 KEP66160.1 - 0.0034 17.0 0.1 0.0084 15.7 0.1 1.7 1 1 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Cellulase-like PF12876.2 KEP66160.1 - 0.065 13.6 0.0 0.078 13.4 0.0 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like IMCp PF12314.3 KEP66161.1 - 9.1e-06 25.7 0.0 0.00046 20.2 0.0 2.8 1 1 1 3 3 3 1 Inner membrane complex protein Drf_FH1 PF06346.7 KEP66161.1 - 3.8e-05 23.2 15.4 0.012 15.1 4.4 2.3 1 1 1 2 2 2 2 Formin Homology Region 1 DUF3248 PF11609.3 KEP66161.1 - 6.7e-05 22.5 12.3 6.8 6.4 0.0 7.0 2 1 6 8 8 8 3 Protein of unknown function (DUF3248) DUF1629 PF07791.6 KEP66161.1 - 0.23 11.3 6.8 53 3.7 2.7 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1629) SIC PF03482.8 KEP66161.1 - 1 8.9 3.3 11 5.5 1.2 2.7 1 1 1 2 2 2 0 sic protein Ret_tiss PF10044.4 KEP66161.1 - 3.9 8.0 6.2 24 5.5 1.0 2.7 1 1 0 2 2 2 0 Retinal tissue protein PX PF00787.19 KEP66162.1 - 1.9e-09 37.2 0.0 0.00017 21.3 0.1 2.6 2 0 0 2 2 2 2 PX domain Dymeclin PF09742.4 KEP66163.1 - 9.6e-37 126.4 0.4 2e-36 125.4 0.1 1.6 2 0 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein GcpE PF04551.9 KEP66165.1 - 1.2e-147 491.4 0.0 6.1e-101 337.7 0.0 2.1 2 0 0 2 2 2 2 GcpE protein GP38 PF05268.6 KEP66165.1 - 0.04 13.3 0.4 0.11 11.9 0.3 1.7 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 ZZ PF00569.12 KEP66166.1 - 1.3e-10 40.6 4.8 2.5e-10 39.7 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KEP66166.1 - 4.9e-08 32.8 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEP66166.1 - 0.00049 20.1 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain AP2 PF00847.15 KEP66166.1 - 0.84 9.8 3.8 8.3 6.6 0.7 2.6 2 0 0 2 2 2 0 AP2 domain HypA PF01155.14 KEP66166.1 - 1.3 8.7 1.1 2.6 7.7 0.8 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Baculo_IE-1 PF05290.6 KEP66166.1 - 6.5 6.4 0.9 11 5.7 0.6 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) WD40 PF00400.27 KEP66167.1 - 1.6e-21 75.2 32.4 6.3e-09 35.3 0.6 8.5 8 1 1 9 9 9 5 WD domain, G-beta repeat TPR_11 PF13414.1 KEP66167.1 - 0.29 10.8 1.9 0.82 9.3 0.6 2.1 1 1 1 2 2 2 0 TPR repeat Lipase_3 PF01764.20 KEP66168.1 - 2.5e-05 23.9 0.0 9.1e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) TLD PF07534.11 KEP66169.1 - 7.7e-30 103.7 0.1 1.8e-29 102.5 0.1 1.7 1 0 0 1 1 1 1 TLD GTP_EFTU PF00009.22 KEP66170.1 - 2.1e-60 203.4 0.0 2.8e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEP66170.1 - 1.9e-24 85.6 0.3 4e-24 84.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEP66170.1 - 2.6e-16 59.4 0.5 5.5e-16 58.4 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEP66170.1 - 3.6e-05 23.6 0.0 0.00011 22.1 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KEP66170.1 - 0.00022 20.8 0.2 0.00065 19.2 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Miro PF08477.8 KEP66170.1 - 0.054 13.9 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein cobW PF02492.14 KEP66170.1 - 0.073 12.5 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ependymin PF00811.13 KEP66170.1 - 0.17 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Ependymin Rad60-SLD PF11976.3 KEP66173.1 - 0.00012 21.6 0.0 0.00032 20.3 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like GABP-alpha PF11620.3 KEP66173.1 - 0.0024 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 GA-binding protein alpha chain ubiquitin PF00240.18 KEP66173.1 - 0.0034 16.7 0.0 0.0076 15.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin family DUF2604 PF10790.4 KEP66173.1 - 0.033 14.3 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) Kelch_1 PF01344.20 KEP66174.1 - 3.8e-51 170.4 0.0 1.1e-11 44.0 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KEP66174.1 - 7e-33 111.4 0.0 3.3e-06 27.0 0.0 6.5 3 2 3 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KEP66174.1 - 2.7e-21 75.0 0.3 0.00034 20.3 0.0 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP66174.1 - 3.4e-17 62.0 0.5 0.003 17.6 0.0 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KEP66174.1 - 3.3e-16 58.3 0.3 0.0056 16.3 0.0 6.7 6 0 0 6 6 6 4 Kelch motif BTB_2 PF02214.17 KEP66174.1 - 4.5e-15 55.6 0.0 1.2e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 KEP66174.1 - 2.3e-10 40.2 0.6 0.19 11.7 0.0 5.6 5 0 0 5 5 5 3 Kelch motif DUF1640 PF07798.6 KEP66174.1 - 2.7 8.0 12.8 4.4 7.3 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Abhydrolase_6 PF12697.2 KEP66175.1 - 1.2e-32 113.6 0.8 1.2e-32 113.6 0.6 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP66175.1 - 1e-10 41.5 0.0 1.6e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP66175.1 - 7.1e-07 29.0 2.1 0.00013 21.5 0.3 3.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KEP66175.1 - 0.00093 18.8 0.1 0.0031 17.1 0.2 1.7 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.3 KEP66175.1 - 0.0047 16.7 0.1 0.02 14.7 0.1 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Lipase_3 PF01764.20 KEP66175.1 - 0.0079 15.8 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 KEP66175.1 - 0.04 14.1 0.4 0.3 11.2 0.0 2.6 4 0 0 4 4 4 0 Thioesterase domain IQ PF00612.22 KEP66177.1 - 1.1e-11 43.1 19.0 0.0069 15.9 1.0 5.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif TPR_12 PF13424.1 KEP66179.1 - 3.7e-12 46.0 0.6 3.9e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEP66179.1 - 5.5e-10 38.7 1.5 0.00053 19.5 0.1 2.5 2 0 0 2 2 2 2 TPR repeat SHNi-TPR PF10516.4 KEP66179.1 - 9.1e-08 31.2 0.1 1.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 SHNi-TPR TPR_1 PF00515.23 KEP66179.1 - 4.8e-07 29.1 0.3 0.015 14.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP66179.1 - 6.7e-06 25.6 8.3 0.024 14.5 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEP66179.1 - 2e-05 25.1 8.2 0.006 17.2 1.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEP66179.1 - 0.00046 19.7 0.9 0.57 10.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEP66179.1 - 0.0088 15.9 0.6 3.3 7.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEP66179.1 - 0.02 14.6 1.9 2.8 7.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Brr6_like_C_C PF10104.4 KEP66181.1 - 1.8e-24 85.7 0.0 2.6e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain KH_1 PF00013.24 KEP66182.1 - 0.00014 21.4 0.0 0.00037 20.0 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KEP66182.1 - 0.019 14.5 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 KH domain Pex14_N PF04695.8 KEP66183.1 - 1.1 9.3 10.1 10 6.1 4.4 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kinase-like PF14531.1 KEP66184.1 - 6.2e-23 81.1 0.0 8.1e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP66184.1 - 2.8e-22 79.1 0.0 3.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66184.1 - 6.6e-06 25.3 0.0 1.6e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KEP66184.1 - 9.2e-05 21.5 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP66184.1 - 0.0026 17.5 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEP66184.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KEP66184.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PCI_Csn8 PF10075.4 KEP66185.1 - 7.1e-14 51.7 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KEP66185.1 - 3e-09 36.7 0.0 4.7e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF43 PF01861.11 KEP66185.1 - 0.052 12.5 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Alg6_Alg8 PF03155.10 KEP66186.1 - 2e-74 251.1 38.0 1.8e-32 112.7 5.9 6.0 6 0 0 6 6 6 6 ALG6, ALG8 glycosyltransferase family MIP-T3 PF10243.4 KEP66186.1 - 0.0039 15.7 15.1 0.0058 15.1 10.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Plasmodium_Vir PF05795.6 KEP66186.1 - 0.04 13.1 0.6 0.066 12.4 0.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3328 PF11807.3 KEP66186.1 - 0.084 12.5 0.5 21 4.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3328) DUF1510 PF07423.6 KEP66186.1 - 0.11 11.8 13.1 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3989 PF13150.1 KEP66186.1 - 0.95 8.9 0.0 0.95 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) EF-hand_6 PF13405.1 KEP66187.1 - 4.7e-08 32.2 0.0 8.9e-05 22.0 0.0 3.7 3 1 1 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 KEP66187.1 - 3.3e-07 30.3 0.0 0.00066 19.7 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KEP66187.1 - 1.3e-06 27.2 0.2 8.8e-05 21.5 0.0 3.3 4 1 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KEP66187.1 - 4.4e-06 26.2 0.2 0.00065 19.2 0.1 3.2 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.1 KEP66187.1 - 0.00039 19.6 0.1 0.0014 17.9 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.1 KEP66187.1 - 0.03 14.2 0.0 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain AP2 PF00847.15 KEP66188.1 - 5.6e-12 45.6 3.3 0.00011 22.2 0.0 3.5 4 0 0 4 4 4 2 AP2 domain Hom_end_hint PF05203.11 KEP66189.1 - 0.57 9.8 0.1 0.57 9.8 0.0 2.1 1 1 1 2 2 2 0 Hom_end-associated Hint Spore_coat_CotO PF14153.1 KEP66189.1 - 1.1 8.6 22.4 1.2 8.5 15.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 KEP66189.1 - 2.4 7.4 28.6 2.7 7.2 19.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2514 PF10721.4 KEP66190.1 - 0.4 10.3 20.7 0.42 10.2 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TYA PF01021.14 KEP66190.1 - 0.61 10.3 3.3 0.5 10.6 1.6 1.4 1 1 0 1 1 1 0 TYA transposon protein Vfa1 PF08432.5 KEP66190.1 - 3.6 7.5 30.4 3.9 7.4 21.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 KEP66191.1 - 5.3 5.4 7.4 6.4 5.1 5.1 1.0 1 0 0 1 1 1 0 Daxx Family GRASP55_65 PF04495.9 KEP66192.1 - 2.3e-43 147.5 0.0 2.9e-33 114.7 0.0 2.2 1 1 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KEP66192.1 - 1.9e-07 30.8 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 KEP66192.1 - 0.0052 16.9 0.0 0.64 10.2 0.0 2.4 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) CDC45 PF02724.9 KEP66194.1 - 0.26 9.2 4.8 0.027 12.5 0.3 1.5 2 0 0 2 2 2 0 CDC45-like protein ATP-synt_ab PF00006.20 KEP66196.1 - 5.1e-64 215.7 0.0 7.8e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 KEP66196.1 - 2.2e-23 82.2 1.3 3.8e-23 81.4 0.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 KEP66196.1 - 8.5e-21 74.5 0.1 1.5e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain AAA PF00004.24 KEP66196.1 - 0.0029 17.8 0.0 0.13 12.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KEP66196.1 - 0.005 15.9 0.1 0.0091 15.1 0.1 1.5 1 0 0 1 1 1 1 KaiC MobB PF03205.9 KEP66196.1 - 0.022 14.4 0.2 4.3 7.0 0.1 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KEP66196.1 - 0.024 14.0 0.1 0.053 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEP66196.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 KEP66196.1 - 0.041 13.0 0.1 0.081 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 KEP66196.1 - 0.25 10.1 2.0 0.14 10.9 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain Abhydrolase_6 PF12697.2 KEP66199.1 - 6.7e-31 107.9 0.0 1.6e-30 106.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP66199.1 - 2.9e-18 66.2 0.0 2.6e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEP66199.1 - 3.7e-18 65.6 0.0 1.4e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEP66199.1 - 9e-06 25.4 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KEP66199.1 - 7.8e-05 22.0 0.0 0.0008 18.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Ser_hydrolase PF06821.8 KEP66199.1 - 0.00073 19.1 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 KEP66199.1 - 0.0015 18.0 0.0 0.05 13.0 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 KEP66199.1 - 0.021 14.6 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Tat PF00539.13 KEP66199.1 - 0.092 12.3 9.1 0.28 10.8 6.3 1.8 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) DUF676 PF05057.9 KEP66199.1 - 0.26 10.5 0.0 0.76 9.0 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DNA_pol_A PF00476.15 KEP66200.1 - 1.7e-56 191.5 0.0 6.3e-56 189.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 KEP66200.1 - 2.5e-18 66.1 0.0 2.4e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease AAA_25 PF13481.1 KEP66200.1 - 5.4e-17 61.8 0.0 1.3e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Toprim_4 PF13662.1 KEP66200.1 - 2.8e-08 33.6 0.0 6.5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 KEP66200.1 - 2.4e-06 27.7 0.0 7.1e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Toprim-like Toprim_3 PF13362.1 KEP66200.1 - 2.3e-05 24.5 0.0 7.6e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Toprim domain KaiC PF06745.8 KEP66200.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 KaiC EGF_CA PF07645.10 KEP66202.1 - 2.9e-29 100.7 75.8 9.7e-11 41.4 6.3 6.2 6 0 0 6 6 6 5 Calcium-binding EGF domain EGF_3 PF12947.2 KEP66202.1 - 3.2e-20 71.7 64.0 3.7e-06 26.7 6.1 5.9 6 0 0 6 6 6 5 EGF domain cEGF PF12662.2 KEP66202.1 - 2.4e-17 62.2 50.1 1.1e-07 31.3 0.8 6.8 6 1 0 6 6 6 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP66202.1 - 7.4e-13 48.3 58.6 0.00013 21.9 5.2 6.7 3 1 1 6 6 6 5 Coagulation Factor Xa inhibitory site EGF PF00008.22 KEP66202.1 - 2e-10 40.4 56.3 0.0017 18.2 1.6 7.0 6 1 1 7 7 7 5 EGF-like domain EGF_MSP1_1 PF12946.2 KEP66202.1 - 2.9e-06 26.9 59.2 0.00013 21.6 4.8 6.3 6 1 0 6 6 6 4 MSP1 EGF domain 1 hEGF PF12661.2 KEP66202.1 - 0.0028 17.6 28.7 0.0061 16.5 0.7 6.7 6 0 0 6 6 6 2 Human growth factor-like EGF CDP-OH_P_transf PF01066.16 KEP66203.1 - 2.2e-17 63.1 3.2 2.2e-17 63.1 2.2 2.4 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF2818 PF10993.3 KEP66203.1 - 0.56 10.7 5.6 0.48 10.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2818) Baculo_PEP_C PF04513.7 KEP66205.1 - 0.85 9.4 2.6 28 4.5 0.2 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Zip PF02535.17 KEP66208.1 - 1.1e-34 119.9 2.0 7.8e-34 117.1 1.4 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Ank_5 PF13857.1 KEP66209.1 - 1.5e-09 37.7 0.4 2.9e-05 24.1 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEP66209.1 - 1.5e-08 34.8 1.1 9.7e-06 25.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEP66209.1 - 3e-07 29.9 0.0 0.013 15.2 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KEP66209.1 - 4.9e-07 29.3 0.0 0.19 12.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KEP66209.1 - 0.011 16.1 0.1 0.48 11.0 0.0 2.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Mesd PF10185.4 KEP66211.1 - 2.4e-05 24.0 0.0 3.5e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor AAA_22 PF13401.1 KEP66212.1 - 3.1e-09 37.0 0.0 8.6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP66212.1 - 8.2e-05 22.6 0.3 0.00084 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RNase_H2_suC PF08615.6 KEP66213.1 - 1.9e-12 47.1 0.0 1.2e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) WD40 PF00400.27 KEP66216.1 - 0.00012 21.8 0.2 2.1 8.3 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat GILT PF03227.11 KEP66217.1 - 2.7e-24 85.1 1.0 4.9e-24 84.2 0.7 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.1 KEP66217.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Defensin_big PF14862.1 KEP66217.1 - 0.09 12.8 1.1 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Big defensin Peptidase_S64 PF08192.6 KEP66218.1 - 0.73 8.0 5.8 0.95 7.7 4.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 ERCC4 PF02732.10 KEP66219.1 - 1.7e-17 63.5 0.0 4.7e-17 62.0 0.0 1.8 1 1 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KEP66219.1 - 0.002 18.2 0.0 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain Peptidase_M24 PF00557.19 KEP66220.1 - 2.2e-39 135.2 0.0 3.2e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KEP66220.1 - 5e-23 82.0 0.0 1.9e-21 76.9 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Ank_2 PF12796.2 KEP66221.1 - 3.8e-38 129.6 3.2 8.9e-20 70.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP66221.1 - 1.5e-36 124.0 3.8 6.6e-13 48.8 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KEP66221.1 - 1.2e-33 113.2 3.2 4e-11 42.1 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KEP66221.1 - 5.7e-27 93.1 2.1 4.2e-09 36.3 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP66221.1 - 4.9e-25 85.0 0.3 1.8e-06 27.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF4265 PF14085.1 KEP66221.1 - 0.092 12.4 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4265) Histone PF00125.19 KEP66222.1 - 3.8e-25 87.8 0.0 5.8e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEP66222.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L7Ae PF01248.21 KEP66223.1 - 3.8e-21 74.4 1.1 7.4e-21 73.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KEP66223.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF2161 PF09929.4 KEP66223.1 - 0.078 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) TBPIP PF07106.8 KEP66224.1 - 2.2e-15 56.6 0.3 4.8e-15 55.5 0.2 1.5 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RNA_pol_L_2 PF13656.1 KEP66225.1 - 5.4e-28 96.2 0.0 6.9e-28 95.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KEP66225.1 - 1.7e-08 33.4 0.0 2.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Asp PF00026.18 KEP66226.1 - 5e-14 52.2 0.0 4.7e-08 32.6 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEP66226.1 - 1e-11 45.0 9.9 1.4e-10 41.3 7.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KEP66226.1 - 1.6e-07 30.9 0.0 0.0077 15.7 0.0 3.5 3 1 0 4 4 4 2 Xylanase inhibitor C-terminal NOGCT PF08155.6 KEP66227.1 - 7e-27 92.8 0.1 1.3e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KEP66227.1 - 8.5e-24 83.2 0.5 2.2e-23 81.8 0.3 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KEP66227.1 - 1.4e-17 63.6 0.0 3.2e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP66227.1 - 1.9e-11 43.4 0.1 3.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEP66227.1 - 0.0025 17.2 0.0 0.007 15.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEP66227.1 - 0.0094 15.7 0.4 5 6.9 0.0 2.7 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KEP66227.1 - 0.023 15.2 0.0 0.066 13.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 KEP66227.1 - 0.11 11.6 0.0 0.71 9.0 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_L22 PF00237.14 KEP66228.1 - 3.3e-05 23.7 0.0 7.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Abhydrolase_5 PF12695.2 KEP66229.1 - 4.2e-17 62.2 0.9 8.5e-17 61.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP66229.1 - 6.5e-11 42.5 4.2 1.5e-09 38.1 0.5 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEP66229.1 - 0.0018 17.7 0.0 0.0097 15.3 0.0 2.2 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KEP66229.1 - 0.0044 16.2 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 KEP66229.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 KEP66229.1 - 0.027 13.6 0.0 0.076 12.2 0.0 1.6 1 1 0 1 1 1 0 Secretory lipase CbiC PF02570.10 KEP66229.1 - 0.037 13.4 0.4 0.07 12.5 0.3 1.4 1 0 0 1 1 1 0 Precorrin-8X methylmutase MtmB PF05369.7 KEP66230.1 - 3.7 5.6 0.5 5.5 5.0 0.3 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB PSS PF03034.10 KEP66231.1 - 2e-93 312.8 3.4 2e-93 312.8 2.4 1.9 2 1 0 2 2 2 1 Phosphatidyl serine synthase Mating_C PF12737.2 KEP66231.1 - 0.026 13.4 7.1 0.048 12.5 4.9 1.4 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Pex14_N PF04695.8 KEP66232.1 - 0.013 15.5 1.9 0.022 14.8 1.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 KEP66232.1 - 0.084 11.1 1.6 0.11 10.7 1.1 1.0 1 0 0 1 1 1 0 Transmembrane protein PT PF04886.7 KEP66232.1 - 0.21 10.9 17.4 0.56 9.5 12.0 1.7 1 0 0 1 1 1 0 PT repeat Pheromone PF08015.6 KEP66232.1 - 1.9 9.3 16.6 1.4 9.7 5.8 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone CytochromB561_N PF09786.4 KEP66232.1 - 2.9 6.2 8.5 4 5.7 5.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal ORC6 PF05460.8 KEP66232.1 - 5.3 6.0 10.4 9.7 5.1 7.2 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) LSM PF01423.17 KEP66233.1 - 7.5e-17 60.6 0.1 8.7e-17 60.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEP66233.1 - 1.6e-07 31.1 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SSrecog PF03531.9 KEP66234.1 - 7.6e-58 195.4 0.2 1.2e-57 194.8 0.1 1.2 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KEP66234.1 - 5.4e-27 93.6 0.0 1.5e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like SURF2 PF05477.6 KEP66234.1 - 0.11 11.5 20.2 0.2 10.7 14.0 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RNase_H2-Ydr279 PF09468.5 KEP66234.1 - 0.13 11.4 9.8 0.21 10.7 6.8 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Nop14 PF04147.7 KEP66234.1 - 0.57 8.0 30.9 0.75 7.6 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_DNAp_acc PF04929.7 KEP66234.1 - 0.92 8.4 11.1 1.3 7.9 7.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CDC45 PF02724.9 KEP66234.1 - 0.96 7.4 24.0 1.3 6.9 16.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 KEP66234.1 - 2.6 6.6 24.2 4.6 5.8 16.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.8 KEP66234.1 - 2.8 7.5 34.8 0.067 12.7 19.7 1.5 2 0 0 2 2 2 0 YL1 nuclear protein Apt1 PF10351.4 KEP66234.1 - 7.1 5.3 14.0 10 4.8 9.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Med12-LCEWAV PF12145.3 KEP66234.1 - 9.9 4.5 12.4 13 4.1 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Arm PF00514.18 KEP66236.1 - 2.4e-13 49.3 0.0 7.3e-05 22.4 0.0 4.4 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEP66236.1 - 0.00024 21.3 1.5 0.068 13.4 0.5 2.7 1 1 1 2 2 2 2 HEAT repeats WAPL PF07814.8 KEP66236.1 - 0.0004 19.2 0.0 0.00078 18.2 0.0 1.5 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DnaJ PF00226.26 KEP66238.1 - 2.5e-06 27.1 0.2 6.1e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain LELP1 PF15042.1 KEP66238.1 - 0.25 11.5 14.7 0.15 12.2 0.2 2.4 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Ribosomal_S8 PF00410.14 KEP66240.1 - 1.3e-16 60.6 0.0 1.5e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Cupin_8 PF13621.1 KEP66242.1 - 3.8e-22 79.0 0.1 8.5e-22 77.8 0.0 1.5 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 KEP66242.1 - 8.1e-22 77.6 0.0 1.4e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KEP66242.1 - 0.012 14.9 0.0 0.024 13.8 0.0 1.6 1 1 0 1 1 1 0 Cupin superfamily protein Cwf_Cwc_15 PF04889.7 KEP66242.1 - 0.83 9.3 9.5 0.075 12.7 0.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Histone PF00125.19 KEP66243.1 - 9.4e-26 89.7 0.0 1.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEP66243.1 - 7.5e-05 22.7 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEP66244.1 - 9e-34 115.4 0.3 1.4e-33 114.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KEP66244.1 - 0.00025 21.1 0.0 0.00037 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEP66244.1 - 0.0047 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 KEP66244.1 - 0.11 12.3 0.1 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ank_2 PF12796.2 KEP66245.1 - 3.8e-61 203.4 10.4 7.8e-17 61.4 0.7 5.6 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEP66245.1 - 1.2e-43 144.7 6.3 3.8e-09 35.9 0.1 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KEP66245.1 - 3.4e-35 119.2 6.1 1.1e-09 38.2 0.6 7.8 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP66245.1 - 1.8e-29 98.7 2.0 4.7e-06 26.3 0.1 10.2 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 KEP66245.1 - 1.6e-28 98.5 2.9 2.8e-08 34.0 0.2 7.7 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Spt4 PF06093.8 KEP66246.1 - 7.4e-30 102.6 0.4 1e-29 102.2 0.3 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger PCI PF01399.22 KEP66247.1 - 1.3e-17 64.0 0.6 7.9e-17 61.4 0.0 2.6 3 1 0 3 3 3 1 PCI domain RabGAP-TBC PF00566.13 KEP66248.1 - 4.1e-45 153.8 0.0 5.8e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GCC2_GCC3 PF07699.8 KEP66249.1 - 1.2e-40 136.8 106.7 3.6e-08 32.8 1.2 13.5 11 1 2 13 13 13 11 GCC2 and GCC3 Kringle PF00051.13 KEP66249.1 - 1.7e-15 56.8 2.6 8.2e-15 54.6 1.8 2.2 1 0 0 1 1 1 1 Kringle domain MAR_sialic_bdg PF10564.4 KEP66249.1 - 1.5e-07 31.1 8.1 4.9e-05 23.0 0.2 3.6 3 0 0 3 3 3 2 Sialic-acid binding micronemal adhesive repeat DUF2730 PF10805.3 KEP66249.1 - 0.087 12.5 7.5 0.096 12.4 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TPT PF03151.11 KEP66250.1 - 1.5e-31 109.1 23.4 4.6e-28 97.7 4.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KEP66250.1 - 4.4e-07 29.9 25.7 0.0012 18.8 4.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KEP66250.1 - 6.2e-07 28.6 14.0 4.1e-06 25.9 8.3 2.5 1 1 1 2 2 2 1 UAA transporter family Nuc_sug_transp PF04142.10 KEP66250.1 - 0.11 11.6 7.9 1.2 8.1 0.4 2.7 3 0 0 3 3 3 0 Nucleotide-sugar transporter Diphthamide_syn PF01866.12 KEP66251.1 - 7.7e-83 278.2 0.0 3.9e-45 154.4 0.0 2.6 2 1 0 2 2 2 2 Putative diphthamide synthesis protein RNB PF00773.14 KEP66252.1 - 2.3e-93 313.0 0.4 4e-93 312.2 0.3 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KEP66252.1 - 0.0082 16.2 0.5 0.055 13.5 0.0 2.7 2 0 0 2 2 2 1 PIN domain P22_Tail-4 PF11650.3 KEP66252.1 - 0.029 13.9 0.1 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 P22 tail accessory factor Pyr_redox_2 PF07992.9 KEP66254.1 - 8e-08 32.3 0.0 1.5e-06 28.2 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEP66254.1 - 0.00071 19.7 0.0 0.98 9.4 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEP66254.1 - 0.0026 17.7 0.0 0.0076 16.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEP66254.1 - 0.0065 16.2 0.0 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KEP66254.1 - 0.048 12.2 0.0 0.14 10.7 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 KEP66254.1 - 0.055 13.8 0.0 12 6.4 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEP66254.1 - 0.061 12.3 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KEP66254.1 - 0.079 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KEP66254.1 - 0.08 11.4 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KEP66254.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Dynein_heavy PF03028.10 KEP66255.1 - 8.1e-222 738.1 0.0 1.5e-221 737.2 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KEP66255.1 - 7.1e-115 382.3 0.2 7.8e-114 378.9 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 KEP66255.1 - 8e-101 337.4 8.6 8e-101 337.4 6.0 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.2 KEP66255.1 - 4.2e-99 330.8 0.0 8.1e-99 329.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 KEP66255.1 - 1.2e-93 313.1 1.1 2.5e-93 312.0 0.4 1.9 2 0 0 2 2 1 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 KEP66255.1 - 1.2e-79 266.4 0.3 2.1e-79 265.5 0.2 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 KEP66255.1 - 6.4e-77 258.6 13.1 1.6e-76 257.3 9.1 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KEP66255.1 - 6.8e-22 77.6 0.0 3.6e-10 39.7 0.0 5.7 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Filamin PF00630.14 KEP66255.1 - 2.8e-15 56.7 0.1 7.9e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat AAA_17 PF13207.1 KEP66255.1 - 3.5e-11 43.9 0.0 0.021 15.6 0.0 5.8 5 0 0 5 5 5 3 AAA domain AAA_22 PF13401.1 KEP66255.1 - 1.5e-09 38.0 5.6 0.016 15.3 0.0 5.8 7 0 0 7 7 4 2 AAA domain AAA_16 PF13191.1 KEP66255.1 - 3.3e-09 37.0 5.1 0.0079 16.1 0.0 6.3 6 0 0 6 6 5 2 AAA ATPase domain AAA PF00004.24 KEP66255.1 - 1.3e-08 35.0 0.3 0.44 10.7 0.0 5.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEP66255.1 - 5.4e-08 33.1 0.4 0.68 10.2 0.0 4.7 4 0 0 4 4 3 2 AAA domain Sigma54_activ_2 PF14532.1 KEP66255.1 - 9.9e-06 25.6 0.2 1.6 8.7 0.0 5.6 6 0 0 6 6 5 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KEP66255.1 - 1e-05 25.6 0.3 3.5 7.8 0.0 3.9 3 0 0 3 3 3 1 RNA helicase ABC_tran PF00005.22 KEP66255.1 - 1.4e-05 25.3 0.0 0.76 10.0 0.0 4.5 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 KEP66255.1 - 2.3e-05 24.3 6.6 0.6 9.9 0.3 5.2 4 1 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.13 KEP66255.1 - 3.5e-05 23.4 0.0 0.012 15.1 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KEP66255.1 - 6.4e-05 22.6 6.7 1.3 8.8 0.0 5.3 5 0 0 5 5 5 2 Part of AAA domain AAA_14 PF13173.1 KEP66255.1 - 6.7e-05 22.7 0.0 0.3 10.9 0.0 4.6 5 0 0 5 5 4 1 AAA domain ATP_bind_1 PF03029.12 KEP66255.1 - 0.00011 21.8 1.6 0.55 9.7 0.0 3.8 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein T2SE PF00437.15 KEP66255.1 - 0.00024 20.1 0.1 0.054 12.3 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein TIG PF01833.19 KEP66255.1 - 0.00028 20.7 1.2 0.00058 19.7 0.8 1.6 1 0 0 1 1 1 1 IPT/TIG domain UPF0079 PF02367.12 KEP66255.1 - 0.00033 20.2 0.3 2.1 7.9 0.0 3.6 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KEP66255.1 - 0.00036 20.2 1.8 0.21 11.2 0.0 4.2 4 0 0 4 4 4 1 NACHT domain Arch_ATPase PF01637.13 KEP66255.1 - 0.00086 19.0 4.0 0.11 12.2 0.0 3.9 4 0 0 4 4 4 1 Archaeal ATPase MobB PF03205.9 KEP66255.1 - 0.0011 18.6 0.4 2.1 8.0 0.1 3.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KEP66255.1 - 0.011 14.8 0.0 0.86 8.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KEP66255.1 - 0.05 13.0 0.1 11 5.5 0.1 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KEP66255.1 - 0.12 11.8 6.2 1.7 8.0 0.0 4.6 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 KEP66255.1 - 1.1 8.9 4.6 6.7 6.3 0.1 3.8 4 0 0 4 4 4 0 NTPase Kelch_3 PF13415.1 KEP66256.1 - 1.5e-28 98.2 3.4 6.4e-08 32.5 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KEP66256.1 - 1e-25 89.2 3.1 8.9e-09 34.9 0.2 3.9 3 2 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KEP66256.1 - 3.3e-14 52.4 0.8 0.00074 19.4 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 KEP66256.1 - 1.9e-12 46.7 0.5 4.9e-06 26.4 0.1 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 KEP66256.1 - 1.2e-06 27.9 2.4 0.0021 17.7 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 KEP66256.1 - 1.5e-06 27.6 3.8 0.0017 17.8 0.1 3.5 3 1 0 3 3 3 2 Kelch motif RAG2 PF03089.9 KEP66256.1 - 0.084 11.5 0.0 0.18 10.5 0.0 1.5 1 0 0 1 1 1 0 Recombination activating protein 2 AAA PF00004.24 KEP66257.1 - 1.8e-43 147.9 0.1 4.5e-43 146.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEP66257.1 - 1.2e-06 28.2 0.0 4.7e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEP66257.1 - 2.5e-06 27.5 0.3 8.2e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEP66257.1 - 7.1e-06 26.1 0.2 0.00031 20.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP66257.1 - 9.1e-06 25.7 0.1 3.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEP66257.1 - 3.4e-05 24.6 0.4 0.00021 22.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEP66257.1 - 4.9e-05 22.5 0.0 9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEP66257.1 - 0.00021 20.9 0.1 0.00046 19.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF2072 PF09845.4 KEP66257.1 - 0.00032 20.6 0.5 0.00083 19.2 0.4 1.7 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) IstB_IS21 PF01695.12 KEP66257.1 - 0.00045 19.6 0.0 0.00092 18.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KEP66257.1 - 0.00083 19.6 0.1 0.0058 16.9 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 KEP66257.1 - 0.0019 18.1 0.0 0.0048 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEP66257.1 - 0.0029 16.3 0.2 0.0097 14.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus Filament PF00038.16 KEP66257.1 - 0.0033 16.9 3.3 0.0092 15.4 2.0 1.7 1 1 0 1 1 1 1 Intermediate filament protein KaiC PF06745.8 KEP66257.1 - 0.0035 16.4 0.1 0.061 12.4 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.1 KEP66257.1 - 0.0036 17.2 0.0 0.0089 15.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 KEP66257.1 - 0.0036 16.4 0.0 0.0096 15.0 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KEP66257.1 - 0.0039 16.6 0.9 0.09 12.1 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.6 KEP66257.1 - 0.0063 16.1 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KEP66257.1 - 0.009 15.9 1.4 0.012 15.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.1 KEP66257.1 - 0.0098 15.4 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEP66257.1 - 0.011 14.9 0.1 0.024 13.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KEP66257.1 - 0.013 14.6 0.1 0.086 12.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 KEP66257.1 - 0.022 14.2 0.0 0.093 12.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_13 PF13166.1 KEP66257.1 - 0.022 13.2 0.1 0.42 9.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KEP66257.1 - 0.026 14.1 0.0 0.61 9.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KEP66257.1 - 0.028 14.5 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KEP66257.1 - 0.037 14.3 0.3 0.24 11.7 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 KEP66257.1 - 0.038 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 KEP66257.1 - 0.044 14.1 1.9 16 5.7 1.7 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KEP66257.1 - 0.053 12.4 0.0 0.099 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 KEP66257.1 - 0.073 12.6 0.5 0.38 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KEP66257.1 - 0.086 12.8 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Rab5-bind PF09311.6 KEP66257.1 - 0.27 11.0 6.2 0.2 11.5 2.7 1.9 2 0 0 2 2 2 0 Rabaptin-like protein HR1 PF02185.11 KEP66257.1 - 6.6 6.5 10.0 0.28 10.9 2.0 2.5 3 0 0 3 3 2 0 Hr1 repeat IncA PF04156.9 KEP66258.1 - 0.09 12.3 2.6 0.098 12.2 1.8 1.0 1 0 0 1 1 1 0 IncA protein Sigma70_ner PF04546.8 KEP66258.1 - 0.85 9.1 7.9 0.93 9.0 5.5 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.3 KEP66258.1 - 1.9 8.3 8.1 1.9 8.3 5.6 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.1 KEP66258.1 - 3.1 7.4 7.1 3.8 7.1 4.9 1.1 1 0 0 1 1 1 0 FAM176 family BTV_NS2 PF04514.7 KEP66258.1 - 7.3 5.3 8.1 6.9 5.4 5.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MutS_V PF00488.16 KEP66259.1 - 3.2e-91 304.9 0.0 5.4e-91 304.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEP66259.1 - 5.3e-24 85.1 1.7 1.2e-23 84.0 1.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KEP66259.1 - 1e-06 28.8 0.3 2.1e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KEP66259.1 - 4.2e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain II ABM PF03992.11 KEP66260.1 - 1.5e-05 24.9 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase zf-CDGSH PF09360.5 KEP66261.1 - 6.5e-10 38.6 0.4 1.1e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type DUF4235 PF14019.1 KEP66261.1 - 0.84 9.5 4.1 1 9.2 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4235) IQ PF00612.22 KEP66263.1 - 0.66 9.7 7.2 2.3 8.0 0.2 3.1 3 0 0 3 3 3 0 IQ calmodulin-binding motif RAP PF08373.5 KEP66268.1 - 4.2e-14 52.0 0.2 9.3e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 RAP domain DNA_primase_S PF01896.14 KEP66269.1 - 9.1e-51 171.4 0.0 7.1e-50 168.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit EF-hand_1 PF00036.27 KEP66270.1 - 5.1e-30 100.4 12.8 2.1e-09 35.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP66270.1 - 1.1e-25 89.5 10.7 3.6e-13 49.4 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP66270.1 - 3.3e-25 85.6 9.8 2.5e-08 33.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KEP66270.1 - 9.1e-22 76.4 19.3 3.6e-14 52.1 1.1 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KEP66270.1 - 9.1e-17 59.5 11.1 1.9e-05 23.7 0.0 4.5 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 KEP66270.1 - 1.3e-13 50.6 0.7 8.8e-06 25.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEP66270.1 - 3.7e-05 23.4 4.4 0.066 12.9 0.0 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.12 KEP66270.1 - 0.016 15.5 0.7 0.016 15.5 0.5 2.3 2 1 0 2 2 2 0 MgtE intracellular N domain Toprim_2 PF13155.1 KEP66270.1 - 0.063 13.6 1.3 1.1 9.6 0.1 2.4 1 1 1 2 2 2 0 Toprim-like Caleosin PF05042.8 KEP66270.1 - 0.073 12.6 0.1 0.86 9.1 0.0 2.3 1 1 1 2 2 2 0 Caleosin related protein FlgD PF03963.9 KEP66270.1 - 0.074 13.1 0.1 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Flagellar hook capping protein - N-terminal region TerB PF05099.8 KEP66270.1 - 0.096 12.4 4.1 4.6 6.9 0.2 2.8 1 1 2 3 3 3 0 Tellurite resistance protein TerB Ribosomal_L11 PF00298.14 KEP66270.1 - 0.15 12.2 0.1 1.8 8.7 0.0 2.4 1 1 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Ribosomal_L23 PF00276.15 KEP66271.1 - 1.1e-08 34.8 0.4 2.9e-08 33.5 0.3 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 Glycos_transf_2 PF00535.21 KEP66272.1 - 5.2e-19 68.5 0.0 7.8e-11 41.9 0.0 2.5 1 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEP66272.1 - 0.00044 20.1 0.1 0.0066 16.2 0.0 2.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KEP66272.1 - 0.09 13.0 0.0 0.34 11.2 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 APG9 PF04109.11 KEP66273.1 - 1.4e-65 221.6 1.2 9.1e-54 182.7 0.0 2.1 2 0 0 2 2 2 2 Autophagy protein Apg9 DUF4014 PF13198.1 KEP66273.1 - 0.054 13.9 5.3 0.049 14.0 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Sec63 PF02889.11 KEP66274.1 - 1.1e-39 136.5 0.0 1.5e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KEP66274.1 - 6.2e-21 73.8 0.6 6.2e-21 73.8 0.4 2.1 2 0 0 2 2 2 1 DnaJ domain WBS_methylT PF12589.3 KEP66276.1 - 8.9e-20 70.9 11.4 8.9e-20 70.9 7.9 2.2 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KEP66276.1 - 7.9e-08 32.6 0.0 1.9e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP66276.1 - 3.3e-05 23.5 0.0 7.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP66276.1 - 4e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP66276.1 - 4.2e-05 24.0 0.1 9.9e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP66276.1 - 0.00032 20.4 0.0 0.004 16.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP66276.1 - 0.0054 16.7 0.3 0.037 14.0 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KEP66276.1 - 0.0063 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 KEP66276.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PUF PF00806.14 KEP66277.1 - 1.8e-52 171.9 0.3 3.8e-06 26.0 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat ODV-E18 PF10717.4 KEP66278.1 - 0.2 11.1 0.6 0.62 9.5 0.4 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 IncA PF04156.9 KEP66278.1 - 2.2 7.8 4.7 4.6 6.7 3.3 1.4 1 0 0 1 1 1 0 IncA protein Rep_fac-A_C PF08646.5 KEP66279.1 - 9.8e-15 54.5 0.2 2e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 KEP66279.1 - 1e-06 28.4 0.2 0.00044 20.0 0.0 3.8 3 1 1 4 4 4 1 OB-fold nucleic acid binding domain DZR PF12773.2 KEP66279.1 - 0.097 12.5 0.6 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KEP66279.1 - 0.1 12.5 0.3 4.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Acetyltransf_1 PF00583.19 KEP66280.1 - 4.1e-09 36.3 0.0 9.4e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEP66280.1 - 5.7e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP66280.1 - 0.00087 18.9 0.0 0.0024 17.5 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KEP66280.1 - 0.013 15.6 0.1 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain IMCp PF12314.3 KEP66281.1 - 2.1e-21 75.8 66.5 8e-11 41.9 10.9 4.4 1 1 3 4 4 4 4 Inner membrane complex protein Sel1 PF08238.7 KEP66282.1 - 1.9e-18 66.4 14.0 3.7e-06 27.3 1.6 4.5 4 0 0 4 4 4 4 Sel1 repeat Phage_int_SAM_1 PF02899.12 KEP66282.1 - 0.062 13.4 0.5 0.25 11.4 0.4 2.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PilJ PF13675.1 KEP66284.1 - 0.18 12.1 0.5 1.1 9.5 0.1 2.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Peptidase_C65 PF10275.4 KEP66285.1 - 7.7e-51 172.8 0.0 4.8e-49 166.9 0.0 2.0 2 0 0 2 2 2 2 Peptidase C65 Otubain OTU PF02338.14 KEP66285.1 - 0.0027 18.2 0.0 0.0098 16.4 0.0 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease COPI_assoc PF08507.5 KEP66286.1 - 4.9e-06 26.2 6.0 7.2e-06 25.7 4.2 1.2 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 KEP66286.1 - 0.0048 16.8 3.0 0.011 15.7 2.1 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2678 PF10856.3 KEP66286.1 - 0.48 10.1 3.5 0.93 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF3040 PF11239.3 KEP66286.1 - 2.7 8.1 10.5 1.1 9.3 3.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) LRR_4 PF12799.2 KEP66288.1 - 4.5e-52 172.9 52.2 1.7e-07 30.6 1.6 14.0 10 3 2 13 13 13 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP66288.1 - 7.5e-31 105.6 56.5 6.6e-10 38.5 2.3 13.2 6 3 13 20 20 20 16 Leucine rich repeat LRR_9 PF14580.1 KEP66288.1 - 2.4e-19 69.5 19.2 3.2e-07 30.0 0.1 7.1 4 3 4 8 8 8 4 Leucine-rich repeat LRR_7 PF13504.1 KEP66288.1 - 9.9e-13 46.0 37.1 4.4 7.9 0.1 17.8 18 0 0 18 18 18 1 Leucine rich repeat LRR_6 PF13516.1 KEP66288.1 - 3.4e-12 45.0 21.4 16 5.9 0.0 15.0 12 2 3 15 15 15 2 Leucine Rich repeat LRR_1 PF00560.28 KEP66288.1 - 2.2e-11 42.1 60.7 0.011 15.6 0.1 18.6 18 2 1 19 19 19 3 Leucine Rich Repeat C2 PF00168.25 KEP66289.1 - 1.1e-29 102.1 0.0 1.3e-05 24.9 0.0 6.5 6 0 0 6 6 6 5 C2 domain FerI PF08151.7 KEP66289.1 - 0.067 13.2 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 FerI (NUC094) domain adh_short PF00106.20 KEP66290.1 - 3.4e-17 62.8 0.1 9e-17 61.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEP66290.1 - 0.00019 21.1 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEP66290.1 - 0.026 13.9 0.0 0.06 12.7 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEP66290.1 - 0.036 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEP66290.1 - 0.072 13.0 0.2 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding DEAD PF00270.24 KEP66291.1 - 3.2e-24 85.3 0.0 1e-22 80.3 0.0 2.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP66291.1 - 6.8e-22 77.1 0.0 2.1e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KEP66291.1 - 0.012 14.6 0.0 0.012 14.6 0.0 3.2 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit CENP-T PF15511.1 KEP66292.1 - 1.7e-05 24.2 21.1 2.1e-05 23.9 14.6 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T DHH PF01368.15 KEP66293.1 - 8.8e-11 41.6 0.0 1.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 KEP66293.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 1 1 0 1 1 1 0 DHHA2 domain Ndc80_HEC PF03801.8 KEP66294.1 - 1e-28 99.7 0.0 2.8e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.6 KEP66294.1 - 1.6e-06 27.0 13.1 1.6e-06 27.0 9.1 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein GAS PF13851.1 KEP66294.1 - 0.00043 19.5 17.5 0.00043 19.5 12.2 2.5 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KEP66294.1 - 0.0012 18.0 0.7 0.0012 18.0 0.5 1.9 2 0 0 2 2 2 1 Reovirus sigma C capsid protein AAA_13 PF13166.1 KEP66294.1 - 0.0036 15.8 9.6 0.0036 15.8 6.7 2.5 2 1 0 2 2 2 1 AAA domain DUF3349 PF11829.3 KEP66294.1 - 0.11 12.9 1.6 0.89 10.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Borrelia_REV PF03978.8 KEP66294.1 - 3.8 7.2 15.1 2.6 7.7 2.5 3.0 2 1 1 3 3 3 0 Borrelia burgdorferi REV protein Baculo_PEP_C PF04513.7 KEP66294.1 - 7.2 6.4 11.0 0.3 10.9 1.6 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mcm10 PF09332.6 KEP66295.1 - 2.8e-16 59.8 11.9 2.8e-16 59.8 8.3 3.4 2 1 2 4 4 4 1 Mcm10 replication factor zf-primase PF09329.6 KEP66295.1 - 5.8e-07 29.0 0.0 1.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Primase zinc finger Borrelia_orfA PF02414.10 KEP66295.1 - 0.52 9.3 4.0 0.86 8.6 2.8 1.2 1 0 0 1 1 1 0 Borrelia ORF-A EMP24_GP25L PF01105.19 KEP66297.1 - 0.48 10.1 1.0 1.4 8.6 0.7 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4250 PF14056.1 KEP66297.1 - 1.4 8.7 3.0 1.7 8.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Plasmodium_Vir PF05795.6 KEP66297.1 - 7.7 5.5 5.4 20 4.2 3.7 1.7 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PH PF00169.24 KEP66300.1 - 5.6e-19 68.2 0.6 6.8e-19 67.9 0.4 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEP66300.1 - 1.9e-09 37.7 1.3 1.1e-08 35.3 0.9 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KEP66300.1 - 8.2e-06 25.8 0.1 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KEP66300.1 - 0.00037 20.3 0.2 0.0028 17.5 0.1 1.9 1 1 0 1 1 1 1 PH domain 3HBOH PF10605.4 KEP66300.1 - 0.13 10.3 0.0 0.16 10.0 0.0 1.0 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) GTP1_OBG PF01018.17 KEP66301.1 - 1.5e-13 50.6 1.3 5.7e-13 48.8 0.9 1.9 1 1 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 KEP66301.1 - 4.2e-12 46.0 0.0 7.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP66301.1 - 4.9e-05 22.6 0.0 9.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KEP66301.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 KEP66301.1 - 0.088 13.3 0.0 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KEP66301.1 - 0.68 9.7 2.1 1 9.1 0.0 2.2 2 1 0 2 2 2 0 Dynamin family CDC45 PF02724.9 KEP66301.1 - 6.3 4.6 10.6 9.8 4.0 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-DNL PF05180.7 KEP66302.1 - 1.5e-28 98.2 0.1 2.6e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KEP66302.1 - 0.1 12.0 0.7 0.23 11.0 0.1 1.8 2 0 0 2 2 2 0 CSL zinc finger zf-H2C2_2 PF13465.1 KEP66302.1 - 0.71 10.2 4.4 12 6.4 0.4 3.0 2 0 0 2 2 2 0 Zinc-finger double domain Noc2 PF03715.8 KEP66304.1 - 4.9e-33 114.2 0.5 8.5e-33 113.4 0.3 1.3 1 0 0 1 1 1 1 Noc2p family ABC_membrane PF00664.18 KEP66305.1 - 2.4e-85 286.3 12.6 3e-47 161.3 2.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEP66305.1 - 6.5e-70 233.7 0.1 4e-35 121.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.1 KEP66305.1 - 7.7e-13 48.7 0.3 7.9e-05 22.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEP66305.1 - 1.1e-12 47.6 6.6 7.6e-06 25.3 0.3 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEP66305.1 - 6.8e-12 45.9 0.1 0.02 14.8 0.0 4.2 3 1 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KEP66305.1 - 1.2e-11 44.9 3.5 1.3e-05 25.2 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KEP66305.1 - 3.6e-08 33.0 0.2 0.28 10.5 0.0 4.4 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 KEP66305.1 - 5.1e-08 32.2 0.0 0.0025 17.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEP66305.1 - 1.7e-07 30.6 0.1 0.022 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KEP66305.1 - 2.3e-07 31.6 0.1 0.043 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KEP66305.1 - 2.4e-07 31.0 4.6 0.013 15.6 0.3 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KEP66305.1 - 2.3e-06 27.4 1.7 0.015 15.2 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 KEP66305.1 - 5.6e-06 25.2 0.4 0.039 12.5 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_5 PF07728.9 KEP66305.1 - 1.5e-05 24.7 0.5 0.29 10.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) Rad17 PF03215.10 KEP66305.1 - 7.2e-05 21.6 0.4 0.073 11.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 KEP66305.1 - 8.5e-05 22.5 0.2 0.088 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEP66305.1 - 0.00012 22.3 1.3 1.2 9.4 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.1 KEP66305.1 - 0.00016 21.5 0.3 3.1 7.7 0.0 4.0 4 1 0 4 4 4 2 AAA domain ATP-synt_ab PF00006.20 KEP66305.1 - 0.00029 20.3 0.3 0.38 10.2 0.0 2.7 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 KEP66305.1 - 0.00045 19.7 0.8 3.3 7.0 0.0 3.9 4 0 0 4 4 4 1 AAA-like domain IstB_IS21 PF01695.12 KEP66305.1 - 0.00054 19.4 2.6 3.2 7.1 0.0 4.3 5 0 0 5 5 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KEP66305.1 - 0.00071 19.7 0.1 2.2 8.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 KEP66305.1 - 0.0013 18.3 0.5 7.2 6.2 0.0 3.8 4 0 0 4 4 4 0 NACHT domain Zeta_toxin PF06414.7 KEP66305.1 - 0.0024 16.9 2.1 1.3 8.0 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 KEP66305.1 - 0.0035 17.2 0.1 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 KEP66305.1 - 0.0048 15.6 0.0 0.21 10.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KEP66305.1 - 0.0076 16.1 0.0 3.8 7.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.17 KEP66305.1 - 0.018 13.9 0.0 4.6 5.9 0.0 2.8 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.1 KEP66305.1 - 0.018 15.0 0.1 0.54 10.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain PRK PF00485.13 KEP66305.1 - 0.021 14.4 0.4 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.4 KEP66305.1 - 0.021 14.2 0.1 2.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 KEP66305.1 - 0.024 13.5 0.1 1.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DEAD PF00270.24 KEP66305.1 - 0.035 13.6 1.6 4.6 6.7 0.3 3.7 3 1 0 3 3 3 0 DEAD/DEAH box helicase DUF87 PF01935.12 KEP66305.1 - 0.043 13.6 0.5 4.9 6.8 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function DUF87 Viral_helicase1 PF01443.13 KEP66305.1 - 0.045 13.2 2.8 4.1 6.8 0.1 2.9 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 KEP66305.1 - 0.057 13.9 0.1 3 8.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KEP66305.1 - 0.16 12.2 0.1 17 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zip PF02535.17 KEP66306.1 - 1.1e-25 90.3 23.0 5.2e-17 61.8 0.3 4.2 3 1 0 3 3 3 3 ZIP Zinc transporter DUF3040 PF11239.3 KEP66306.1 - 0.12 12.4 0.7 0.53 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Cohesin_HEAT PF12765.2 KEP66309.1 - 0.00033 20.5 3.7 0.011 15.6 0.1 3.1 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KEP66309.1 - 0.026 14.5 10.9 2.9 8.2 0.1 5.4 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.2 KEP66310.1 - 1.3e-45 155.3 0.0 2.2e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Ribosomal_60s PF00428.14 KEP66311.1 - 5.8e-25 87.4 8.9 5.8e-25 87.4 6.2 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein K_channel_TID PF07941.6 KEP66311.1 - 0.017 15.2 3.3 0.017 15.2 2.3 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Cyclin_N PF00134.18 KEP66312.1 - 3.5e-08 33.0 0.3 7e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Med19 PF10278.4 KEP66312.1 - 0.0054 16.4 6.0 0.0054 16.4 4.2 2.0 2 0 0 2 2 2 1 Mediator of RNA pol II transcription subunit 19 UreF PF01730.11 KEP66312.1 - 0.14 12.2 2.3 2.5 8.2 0.1 2.6 2 0 0 2 2 2 0 UreF Cnd1_N PF12922.2 KEP66312.1 - 1.3 8.6 8.7 0.065 12.8 0.3 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term NST1 PF13945.1 KEP66312.1 - 1.5 8.8 11.1 0.09 12.8 2.5 2.5 2 0 0 2 2 2 0 Salt tolerance down-regulator CAF1 PF04857.15 KEP66313.1 - 6e-67 225.7 0.5 8.1e-67 225.3 0.3 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Mpp10 PF04006.7 KEP66314.1 - 0.00062 18.2 18.4 0.00065 18.1 12.8 1.0 1 0 0 1 1 1 1 Mpp10 protein Daxx PF03344.10 KEP66314.1 - 0.028 12.9 26.9 0.033 12.7 18.6 1.0 1 0 0 1 1 1 0 Daxx Family Trypan_PARP PF05887.6 KEP66314.1 - 0.076 12.8 18.5 0.1 12.4 12.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ycf1 PF05758.7 KEP66314.1 - 0.098 10.3 10.7 0.11 10.2 7.4 1.0 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 KEP66314.1 - 0.14 10.6 26.2 0.17 10.3 18.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 VID27 PF08553.5 KEP66314.1 - 0.33 9.1 14.9 0.36 9.0 10.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TEX19 PF15553.1 KEP66314.1 - 0.68 9.7 17.7 0.92 9.3 12.2 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 Pilt PF15453.1 KEP66314.1 - 0.69 9.5 13.1 0.8 9.3 9.1 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SAPS PF04499.10 KEP66314.1 - 0.89 8.1 10.0 1 7.9 7.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 KEP66314.1 - 0.96 8.7 25.6 1.2 8.5 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 KEP66314.1 - 1.8 7.5 4.6 1.8 7.4 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3381 PF11861.3 KEP66314.1 - 3 7.3 22.3 3.9 6.9 15.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4246 PF14033.1 KEP66314.1 - 3.3 6.2 9.9 3.5 6.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) eIF-3c_N PF05470.7 KEP66314.1 - 5.7 4.9 12.8 6.3 4.7 8.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Raftlin PF15250.1 KEP66314.1 - 6.1 5.2 9.7 6.9 5.0 6.7 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.9 KEP66314.1 - 6.1 4.7 23.4 7.1 4.5 16.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KEP66314.1 - 6.4 4.3 8.1 7.4 4.1 5.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2457 PF10446.4 KEP66314.1 - 8.5 4.9 25.0 10 4.7 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KEP66314.1 - 9.6 5.3 14.4 11 5.1 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2201_N PF13203.1 KEP66314.1 - 9.8 5.2 15.9 12 4.9 11.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain BT1 PF03092.11 KEP66316.1 - 1.7e-79 267.5 11.4 2.3e-79 267.1 7.9 1.2 1 0 0 1 1 1 1 BT1 family MMR_HSR1 PF01926.18 KEP66317.1 - 5.8e-06 26.2 0.0 1.8e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEP66317.1 - 0.00073 19.0 0.1 1.6 8.1 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF2889 PF11136.3 KEP66317.1 - 0.0047 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2889) PduV-EutP PF10662.4 KEP66317.1 - 0.01 15.3 0.1 0.45 9.9 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KEP66317.1 - 0.019 14.8 0.4 2.1 8.1 0.0 2.9 4 0 0 4 4 4 0 Dynamin family MobB PF03205.9 KEP66317.1 - 0.024 14.3 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad50_zn_hook PF04423.9 KEP66317.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif OB_NTP_bind PF07717.11 KEP66318.1 - 2.4e-26 91.8 0.0 6.8e-26 90.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEP66318.1 - 5.1e-24 84.2 0.5 3.7e-23 81.4 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEP66318.1 - 8.3e-10 38.3 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP66318.1 - 7.2e-06 25.5 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KEP66318.1 - 0.00067 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KEP66318.1 - 0.0055 16.5 0.0 3.6 7.3 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEP66318.1 - 0.013 15.6 2.5 0.023 14.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KEP66318.1 - 0.092 13.0 0.2 0.4 10.9 0.0 2.3 2 0 0 2 2 1 0 ABC transporter Miro PF08477.8 KEP66318.1 - 0.12 12.8 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KEP66318.1 - 0.19 11.1 4.1 1.1 8.6 0.0 2.8 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KEP66318.1 - 0.27 11.5 0.0 0.27 11.5 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 KEP66318.1 - 3.9 7.4 10.5 0.91 9.4 0.0 3.7 2 1 1 3 3 3 0 AAA ATPase domain MAR_sialic_bdg PF10564.4 KEP66319.1 - 5e-52 173.7 35.6 1.2e-18 66.6 0.9 4.1 3 1 1 4 4 4 4 Sialic-acid binding micronemal adhesive repeat Invasin_D3 PF09134.5 KEP66319.1 - 0.078 12.8 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Invasin, domain 3 DUF3605 PF12239.3 KEP66319.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) GTP_EFTU PF00009.22 KEP66321.1 - 1.3e-54 184.4 0.0 2.1e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KEP66321.1 - 3.8e-31 106.7 0.1 7.8e-31 105.7 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KEP66321.1 - 5.7e-31 106.5 0.0 1.7e-30 105.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KEP66321.1 - 1.5e-24 85.6 0.0 5.6e-24 83.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEP66321.1 - 4.7e-13 49.0 0.0 1.1e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 CbiA PF01656.18 KEP66321.1 - 0.087 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Condensation PF00668.15 KEP66321.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Nol1_Nop2_Fmu PF01189.12 KEP66322.1 - 5.9e-11 42.2 0.0 6.9e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Pex14_N PF04695.8 KEP66322.1 - 0.0097 15.9 0.9 0.0097 15.9 0.6 3.8 5 0 0 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Apc3 PF12895.2 KEP66323.1 - 0.0038 17.3 4.2 0.18 11.9 0.4 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEP66323.1 - 0.022 14.7 9.7 0.24 11.3 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEP66323.1 - 0.036 13.9 13.3 0.42 10.6 0.7 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 KEP66323.1 - 0.058 13.4 0.1 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 PPR repeat TPR_1 PF00515.23 KEP66323.1 - 0.079 12.5 5.0 7.3 6.3 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEP66323.1 - 0.14 11.8 5.8 1.3 8.7 0.3 3.8 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.1 KEP66323.1 - 1.1 9.1 3.0 14 5.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP66323.1 - 1.5 9.4 8.2 11 6.7 0.7 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PMI_typeI PF01238.16 KEP66324.1 - 8.6e-71 238.8 0.1 7.5e-34 117.2 0.0 4.1 4 0 0 4 4 4 4 Phosphomannose isomerase type I Pkinase PF00069.20 KEP66325.1 - 1.5e-16 60.3 0.0 2.8e-08 33.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain DUF4605 PF15378.1 KEP66326.1 - 0.055 13.1 3.0 0.082 12.6 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) Acetyltransf_1 PF00583.19 KEP66327.1 - 6.1e-11 42.2 0.1 9.4e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEP66327.1 - 4.1e-06 26.8 0.0 6.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEP66327.1 - 0.00026 21.0 0.1 0.00037 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP66327.1 - 0.028 14.1 0.0 0.14 11.9 0.0 2.0 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_4 PF13420.1 KEP66327.1 - 0.058 13.3 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SAC3_GANP PF03399.11 KEP66329.1 - 7.8e-45 152.9 0.2 1.2e-44 152.2 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DnaJ PF00226.26 KEP66330.1 - 5.4e-23 80.5 0.5 1.3e-22 79.3 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KEP66330.1 - 2.8e-13 50.0 0.3 6.3e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 KEP66330.1 - 0.07 13.0 1.6 1 9.4 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP66330.1 - 0.08 13.6 0.5 0.08 13.6 0.3 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RPT PF13446.1 KEP66330.1 - 0.092 12.1 0.0 0.36 10.2 0.0 2.0 1 0 0 1 1 1 0 A repeated domain in UCH-protein TPR_16 PF13432.1 KEP66330.1 - 0.28 11.9 4.6 0.34 11.6 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Macoilin PF09726.4 KEP66330.1 - 7.9 4.6 14.7 12 4.0 10.2 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF1448 PF07289.6 KEP66332.1 - 3.1e-61 207.1 0.0 4.8e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) zf-C3HC4_3 PF13920.1 KEP66332.1 - 1.9e-11 43.4 11.7 1.9e-11 43.4 8.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) GRAM PF02893.15 KEP66332.1 - 8.5e-06 25.2 0.0 2.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain zf-C3HC4_2 PF13923.1 KEP66332.1 - 0.00018 21.4 14.4 0.00042 20.2 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps36_ESCRT-II PF11605.3 KEP66332.1 - 0.00054 19.7 0.0 0.056 13.2 0.0 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GDA1_CD39 PF01150.12 KEP66333.1 - 1.7e-29 102.6 0.0 1e-18 67.0 0.0 3.2 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Carb_anhydrase PF00194.16 KEP66334.1 - 2.6e-18 65.9 1.0 9e-13 47.7 0.0 3.3 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase SPC12 PF06645.8 KEP66335.1 - 0.099 12.4 0.6 0.48 10.2 0.4 2.2 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MMR_HSR1 PF01926.18 KEP66336.1 - 4.4e-09 36.3 0.0 8.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEP66336.1 - 0.011 15.6 0.0 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 Dynamin family DUF258 PF03193.11 KEP66336.1 - 0.037 13.2 0.0 0.26 10.4 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF1631 PF07793.6 KEP66337.1 - 0.083 11.0 0.8 0.088 10.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Caudal_act PF04731.7 KEP66337.1 - 0.23 11.7 3.9 0.3 11.3 2.2 1.5 2 0 0 2 2 2 0 Caudal like protein activation region DUF883 PF05957.8 KEP66338.1 - 0.0067 16.7 1.5 0.0067 16.7 1.1 8.5 4 3 6 10 10 10 4 Bacterial protein of unknown function (DUF883) DUF963 PF06131.6 KEP66338.1 - 4.2 6.7 15.8 0.073 12.3 5.0 2.6 2 1 1 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF3360 PF11840.3 KEP66339.1 - 0.064 11.5 0.1 0.078 11.3 0.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3360) Kazal_1 PF00050.16 KEP66340.1 - 6.6e-111 362.1 160.5 2.6e-11 43.3 2.7 13.5 8 2 5 13 13 13 13 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KEP66340.1 - 2.4e-107 350.6 140.7 7.8e-12 44.9 0.7 13.6 13 0 0 13 13 13 13 Kazal-type serine protease inhibitor domain Syja_N PF02383.13 KEP66342.1 - 2.6e-23 82.2 0.0 1.5e-13 50.2 0.0 3.6 3 1 0 3 3 3 3 SacI homology domain Myb_DNA-binding PF00249.26 KEP66343.1 - 0.037 14.1 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain SpoU_methylas_C PF12105.3 KEP66344.1 - 0.024 14.1 0.2 0.071 12.6 0.1 1.8 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal DUF3292 PF11696.3 KEP66345.1 - 0.88 7.3 0.0 2.1 6.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DAGK_cat PF00781.19 KEP66346.1 - 2.2e-13 49.7 0.1 6.6e-13 48.2 0.0 1.7 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.14 KEP66346.1 - 3.1e-13 50.1 0.0 5.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain NAD_kinase PF01513.16 KEP66346.1 - 0.017 13.8 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase EF-hand_1 PF00036.27 KEP66348.1 - 3.8e-17 60.2 4.9 9.4e-06 24.5 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KEP66348.1 - 2e-14 53.4 2.2 1.1e-08 35.0 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP66348.1 - 2.9e-14 51.6 4.0 0.00012 21.6 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KEP66348.1 - 5.2e-12 44.5 6.5 0.00018 20.7 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 KEP66348.1 - 3.1e-08 33.0 7.5 9e-05 22.0 0.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEP66348.1 - 0.0037 17.2 1.6 1.8 8.5 0.1 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SpaB_C PF14028.1 KEP66348.1 - 0.0055 16.2 0.3 0.0066 16.0 0.2 1.1 1 0 0 1 1 1 1 SpaB C-terminal domain MARVEL PF01284.18 KEP66349.1 - 0.018 14.8 8.9 0.67 9.7 6.2 2.5 1 1 0 1 1 1 0 Membrane-associating domain DUF420 PF04238.7 KEP66349.1 - 0.26 11.2 3.5 0.5 10.3 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF420) OMPdecase PF00215.19 KEP66350.1 - 4.2e-28 98.2 0.0 2.9e-26 92.2 0.0 2.1 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2859 PF11072.3 KEP66350.1 - 0.04 13.3 0.0 0.093 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) VWA PF00092.23 KEP66351.1 - 8.9e-46 155.8 0.0 6e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 KEP66351.1 - 9.8e-21 74.6 0.0 1.4e-10 41.5 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.1 KEP66351.1 - 7.6e-11 41.9 0.0 3.6e-07 29.9 0.0 2.5 2 1 0 2 2 2 2 von Willebrand factor type A domain DUF4366 PF14283.1 KEP66351.1 - 0.028 13.8 0.1 0.028 13.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Pribosyltran PF00156.22 KEP66352.1 - 8.6e-11 41.6 0.0 2.1e-10 40.3 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain zf-met PF12874.2 KEP66353.1 - 1.3e-06 28.3 0.3 1.3e-06 28.3 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEP66353.1 - 0.003 17.6 1.9 0.003 17.6 1.3 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KEP66353.1 - 0.036 14.1 0.9 0.086 12.9 0.6 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Nucleoporin_FG PF13634.1 KEP66354.1 - 2.7e-45 153.2 396.4 6.9e-12 45.6 34.9 11.1 2 2 9 11 11 11 10 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 KEP66354.1 - 2.3e-34 118.2 0.0 3.9e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.3 KEP66354.1 - 6.3e-08 32.0 0.0 1.4e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Nuclear protein 96 Gypsy PF07253.6 KEP66354.1 - 8.4 4.5 0.0 13 3.9 0.0 1.1 1 0 0 1 1 1 0 Gypsy protein DUF4403 PF14356.1 KEP66356.1 - 0.04 12.2 0.1 0.056 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) RRM_1 PF00076.17 KEP66358.1 - 0.029 14.0 0.4 14 5.4 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3382 PF11862.3 KEP66359.1 - 3.5 7.5 9.8 0.33 10.8 1.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) TFIIA PF03153.8 KEP66360.1 - 0.055 13.3 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exo_endo_phos PF03372.18 KEP66361.1 - 1e-22 81.3 0.0 4.6e-21 75.8 0.0 2.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CHC2 PF01807.15 KEP66361.1 - 3 7.4 5.5 5.8 6.5 3.8 1.4 1 0 0 1 1 1 0 CHC2 zinc finger Pterin_bind PF00809.17 KEP66362.1 - 1.4e-59 201.0 0.0 2.1e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KEP66362.1 - 1.3e-17 63.6 0.0 3.2e-09 36.5 0.1 2.5 2 0 0 2 2 2 2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Glycos_transf_2 PF00535.21 KEP66363.1 - 2.5e-22 79.3 0.0 4.7e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 KEP66363.1 - 9.2e-06 25.7 0.1 2.7e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 KEP66363.1 - 3.8e-05 23.0 0.0 8.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 KEP66363.1 - 0.088 11.8 0.0 2.7 6.9 0.0 2.5 3 0 0 3 3 3 0 Glycosyltransferase like family 2 DUF3161 PF11362.3 KEP66364.1 - 4.8e-11 42.4 0.0 8.8e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) NEMO PF11577.3 KEP66364.1 - 0.19 11.4 2.5 9 6.1 0.1 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Spectrin PF00435.16 KEP66364.1 - 5.2 7.4 7.3 1.1 9.5 0.5 2.9 4 0 0 4 4 4 0 Spectrin repeat SAG PF04092.8 KEP66365.1 - 4.7e-24 85.1 17.7 4.9e-08 33.4 0.3 3.5 3 0 0 3 3 3 3 SRS domain SAG PF04092.8 KEP66366.1 - 7.1e-17 61.9 4.3 1.1e-09 38.7 0.6 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP66367.1 - 3.6e-14 53.2 13.5 5.4e-09 36.4 3.1 2.5 3 0 0 3 3 3 2 SRS domain SAG PF04092.8 KEP66369.1 - 1.9e-26 92.8 23.4 5e-10 39.8 2.4 3.4 3 0 0 3 3 3 3 SRS domain SAG PF04092.8 KEP66370.1 - 0.0084 16.4 0.1 0.0097 16.2 0.1 1.1 1 0 0 1 1 1 1 SRS domain DUF769 PF05590.6 KEP66370.1 - 0.055 12.6 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) tRNA_edit PF04073.10 KEP66370.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Peptidase_M41 PF01434.13 KEP66371.1 - 1.2e-65 220.9 0.6 1.8e-65 220.4 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEP66371.1 - 1.1e-41 142.1 0.0 2.9e-41 140.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEP66371.1 - 1e-06 28.8 0.4 7.5e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KEP66371.1 - 1.7e-06 28.8 0.0 6.5e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEP66371.1 - 2e-06 27.5 0.0 1e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KEP66371.1 - 8e-05 21.5 0.0 0.00014 20.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KEP66371.1 - 0.00013 21.1 0.0 0.00062 18.8 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEP66371.1 - 0.00073 19.6 0.0 0.02 15.0 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 KEP66371.1 - 0.00079 19.1 0.2 0.0036 17.0 0.1 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 KEP66371.1 - 0.00084 19.2 0.0 0.0041 17.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 KEP66371.1 - 0.001 19.0 0.5 0.0058 16.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEP66371.1 - 0.0027 17.1 0.1 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KEP66371.1 - 0.0056 15.8 1.3 0.0078 15.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 KEP66371.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEP66371.1 - 0.053 13.1 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 KEP66371.1 - 0.055 12.8 0.4 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KEP66371.1 - 0.059 12.5 0.1 0.2 10.7 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KEP66371.1 - 0.17 11.1 0.7 0.43 9.7 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein Helicase_C PF00271.26 KEP66372.1 - 1.4e-15 56.9 0.0 4.2e-14 52.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP66372.1 - 1.2e-12 47.6 0.0 2.8e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KEP66372.1 - 0.00037 20.3 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_S21e PF01249.13 KEP66373.1 - 2.2e-38 130.0 0.0 2.4e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Phage_integrase PF00589.17 KEP66374.1 - 4.2e-18 65.5 0.0 9.6e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family SAP PF02037.22 KEP66374.1 - 7.9e-06 25.2 0.2 1.7e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 SAP domain DZR PF12773.2 KEP66374.1 - 0.0022 17.7 1.4 0.0022 17.7 0.9 2.0 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 KEP66374.1 - 0.0053 16.2 3.9 0.012 15.0 2.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 KEP66374.1 - 0.026 13.7 5.2 0.061 12.5 3.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DEAD PF00270.24 KEP66375.1 - 3.1e-33 114.6 0.0 7.2e-33 113.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP66375.1 - 1.1e-16 60.4 0.0 8.7e-11 41.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEP66375.1 - 0.00018 21.4 0.0 0.00018 21.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit FBA_1 PF07734.8 KEP66375.1 - 0.14 11.7 0.1 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 F-box associated Cupin_8 PF13621.1 KEP66376.1 - 4.5e-20 72.2 0.0 1.9e-18 66.8 0.0 2.6 2 1 0 2 2 2 2 Cupin-like domain Na_H_Exchanger PF00999.16 KEP66378.1 - 8.5e-39 133.1 26.0 8.5e-39 133.1 18.0 1.8 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family DUF3042 PF11240.3 KEP66379.1 - 0.29 10.9 1.8 0.79 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) PALP PF00291.20 KEP66380.1 - 2.7e-59 200.8 0.8 4.1e-59 200.2 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KEP66380.1 - 5.5e-09 35.6 3.4 8.3e-07 28.7 0.2 3.1 4 0 0 4 4 4 2 CBS domain Methyltransf_12 PF08242.7 KEP66380.1 - 0.01 16.3 0.0 0.48 10.9 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L7Ae PF01248.21 KEP66380.1 - 0.038 13.4 0.1 0.24 10.9 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GLE1 PF07817.8 KEP66381.1 - 1.3e-28 99.6 0.5 1.3e-28 99.6 0.4 1.9 2 0 0 2 2 2 1 GLE1-like protein RIX1 PF08167.7 KEP66381.1 - 0.033 13.8 1.0 0.089 12.4 0.1 2.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Borrelia_P83 PF05262.6 KEP66381.1 - 1.2 7.3 38.5 2 6.5 26.7 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.11 KEP66381.1 - 5.6 5.4 9.2 8.2 4.8 6.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA PF00004.24 KEP66382.1 - 0.0046 17.1 0.0 0.033 14.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEP66382.1 - 0.0094 15.6 0.1 0.031 14.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KEP66382.1 - 0.011 15.4 1.7 0.021 14.4 0.6 2.0 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 KEP66382.1 - 0.012 15.6 0.1 0.037 14.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEP66382.1 - 0.012 15.0 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KEP66382.1 - 0.02 14.7 0.2 0.069 13.0 0.2 2.0 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEP66382.1 - 0.042 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 KEP66382.1 - 0.21 11.8 0.0 0.21 11.8 0.0 4.2 4 1 0 4 4 4 0 AAA domain Sigma70_ner PF04546.8 KEP66383.1 - 0.52 9.8 9.4 0.54 9.8 6.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 KEP66383.1 - 0.52 8.1 17.9 0.58 8.0 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 KEP66383.1 - 1.3 8.3 9.2 1.5 8.1 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2890 PF11081.3 KEP66383.1 - 1.9 8.4 10.0 2.4 8.1 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CobT PF06213.7 KEP66383.1 - 2.7 7.0 16.8 3.2 6.7 11.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleoplasmin PF03066.10 KEP66383.1 - 6.2 6.3 12.5 9.1 5.7 8.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOG1 PF06858.9 KEP66384.1 - 1.9e-11 43.6 0.0 9.2e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KEP66384.1 - 8.6e-05 22.4 0.0 0.002 18.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 KEP66384.1 - 0.0063 15.9 2.0 0.073 12.4 0.0 2.9 2 1 1 3 3 3 1 AAA domain FeoB_N PF02421.13 KEP66384.1 - 0.03 13.6 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 KEP66384.1 - 0.055 13.3 0.0 9.7 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4638 PF15472.1 KEP66384.1 - 4.8 6.6 20.2 0.097 12.2 8.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) DUF3995 PF13160.1 KEP66386.1 - 0.99 9.4 10.7 0.42 10.6 2.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) 2OG-FeII_Oxy_2 PF13532.1 KEP66387.1 - 6e-27 94.7 0.0 2.7e-24 86.0 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily UbiA PF01040.13 KEP66388.1 - 5.8e-35 120.7 12.4 5.8e-35 120.7 8.6 1.8 2 1 0 2 2 2 1 UbiA prenyltransferase family ABC1 PF03109.11 KEP66389.1 - 1.6e-14 53.8 0.0 3.6e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 KEP66389.1 - 0.002 17.9 1.2 0.0083 15.8 0.3 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family UQ_con PF00179.21 KEP66390.1 - 5.8e-26 90.6 0.0 9e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEP66390.1 - 0.028 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 KEP66390.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Glyco_transf_7C PF02709.9 KEP66392.1 - 4.1e-07 29.3 0.0 8.4e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 KEP66392.1 - 0.00021 20.7 0.0 0.0063 15.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of glycosyl transferase group 7 Acetyltransf_1 PF00583.19 KEP66393.1 - 2.3e-11 43.5 0.0 3.3e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KEP66393.1 - 3.7e-06 26.8 1.3 5e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEP66393.1 - 9.2e-06 25.7 0.2 4.7e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEP66393.1 - 1.7e-05 24.4 0.1 0.00083 19.0 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 KEP66393.1 - 8.2e-05 22.6 0.3 0.00044 20.3 0.1 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEP66393.1 - 0.00096 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Birna_VP3 PF01767.11 KEP66393.1 - 0.026 14.1 4.9 0.046 13.3 3.4 1.3 1 0 0 1 1 1 0 Birnavirus VP3 protein Nop16 PF09420.5 KEP66393.1 - 0.066 13.3 6.5 0.12 12.4 4.5 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 RNA_pol_Rpc4 PF05132.9 KEP66393.1 - 5.5 6.9 7.4 5.8 6.8 1.1 2.8 3 0 0 3 3 3 0 RNA polymerase III RPC4 Orai-1 PF07856.7 KEP66394.1 - 0.19 11.3 7.2 0.6 9.6 5.0 1.7 1 1 0 1 1 1 0 Mediator of CRAC channel activity DUF3043 PF11241.3 KEP66396.1 - 0.0034 16.9 2.9 0.0047 16.5 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3043) Carboxyl_trans PF01039.17 KEP66396.1 - 0.0043 15.4 0.2 0.0053 15.1 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain DUF3742 PF12553.3 KEP66396.1 - 0.046 14.1 0.1 0.079 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Gastrin PF00918.12 KEP66396.1 - 0.13 13.0 2.1 0.24 12.2 1.5 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family HSP20 PF00011.16 KEP66397.1 - 4e-20 71.5 0.5 5.4e-20 71.1 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 KEP66397.1 - 0.00046 19.8 0.5 0.0011 18.5 0.4 1.6 2 0 0 2 2 2 1 GvpH vATP-synt_AC39 PF01992.11 KEP66398.1 - 3.6e-60 203.8 0.2 7.2e-30 104.2 0.0 2.0 2 0 0 2 2 2 2 ATP synthase (C/AC39) subunit DUF1077 PF06417.7 KEP66399.1 - 3.7e-24 84.4 0.1 8.4e-24 83.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1077) Bromodomain PF00439.20 KEP66400.1 - 2.6e-34 117.0 0.0 6.6e-18 64.4 0.0 2.3 2 0 0 2 2 2 2 Bromodomain Rcd1 PF04078.8 KEP66401.1 - 7.6e-127 421.5 0.5 9e-127 421.3 0.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TPR_6 PF13174.1 KEP66401.1 - 0.11 13.0 0.4 1.3 9.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3587 PF12132.3 KEP66402.1 - 1.8 7.7 0.1 3.2 6.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) Pombe_5TM PF09437.5 KEP66402.1 - 2.6 7.4 0.0 5.1 6.4 0.0 1.4 1 0 0 1 1 1 0 Pombe specific 5TM protein Lectin_leg-like PF03388.8 KEP66403.1 - 5.4e-14 51.8 0.0 2.3e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Legume-like lectin family SF-assemblin PF06705.6 KEP66403.1 - 0.11 11.6 0.2 0.21 10.6 0.1 1.3 1 1 0 1 1 1 0 SF-assemblin/beta giardin AIP3 PF03915.8 KEP66403.1 - 0.11 11.3 1.5 0.16 10.8 1.1 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 HsbA PF12296.3 KEP66403.1 - 0.12 12.2 0.2 0.25 11.2 0.2 1.5 1 1 0 1 1 1 0 Hydrophobic surface binding protein A DUF1690 PF07956.6 KEP66403.1 - 0.22 11.4 0.2 0.37 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Acylphosphatase PF00708.13 KEP66404.1 - 2.2e-26 91.7 0.0 2.6e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Rotamase PF00639.16 KEP66405.1 - 5.4e-24 84.7 0.0 6.2e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KEP66405.1 - 6.9e-20 71.4 0.0 7.6e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KEP66405.1 - 9e-08 32.7 0.0 1.1e-07 32.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain zf-RING_2 PF13639.1 KEP66406.1 - 0.13 12.1 6.2 0.26 11.1 4.3 1.6 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 KEP66406.1 - 0.57 9.9 5.3 0.22 11.2 1.1 2.0 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 KEP66406.1 - 0.88 9.3 5.7 0.11 12.1 0.7 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 F-box-like PF12937.2 KEP66408.1 - 0.00047 19.8 2.8 0.00052 19.6 0.6 2.3 2 0 0 2 2 2 1 F-box-like Herpes_capsid PF06112.6 KEP66409.1 - 0.88 9.6 6.7 4.2 7.4 4.7 1.9 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein Ax_dynein_light PF10211.4 KEP66410.1 - 2.5e-49 167.7 7.6 3.2e-49 167.3 5.3 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain bZIP_2 PF07716.10 KEP66410.1 - 0.012 15.4 1.0 0.012 15.4 0.7 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Vps52 PF04129.7 KEP66415.1 - 1.4e-68 231.6 1.1 2.6e-67 227.5 0.8 2.2 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KEP66415.1 - 1.4e-07 30.1 1.1 0.0002 19.6 0.2 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 DAHP_synth_2 PF01474.11 KEP66415.1 - 0.026 12.8 0.6 0.12 10.6 0.1 2.1 2 0 0 2 2 2 0 Class-II DAHP synthetase family Thioredoxin PF00085.15 KEP66416.1 - 5.1e-08 32.5 0.0 7.6e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 KEP66416.1 - 0.017 15.1 0.0 0.06 13.3 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 KEP66416.1 - 0.067 13.1 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin Spore_YtfJ PF09579.5 KEP66416.1 - 0.19 11.6 0.1 0.61 9.9 0.1 1.8 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Thioredoxin_2 PF13098.1 KEP66416.1 - 0.2 11.8 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Corona_S2 PF01601.11 KEP66416.1 - 0.65 8.0 0.0 1 7.3 0.0 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein SAG PF04092.8 KEP66418.1 - 8.2e-11 42.3 3.6 0.00035 20.9 1.2 3.3 1 1 1 2 2 2 2 SRS domain DZR PF12773.2 KEP66418.1 - 0.19 11.5 2.5 15 5.5 0.2 2.7 2 0 0 2 2 2 0 Double zinc ribbon DUF2797 PF10977.3 KEP66418.1 - 0.42 10.2 2.0 13 5.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) Pkinase_Tyr PF07714.12 KEP66419.1 - 0.13 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.1 KEP66420.1 - 0.08 11.8 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.1 KEP66421.1 - 1.3e-07 31.3 12.6 1.3e-07 31.3 8.7 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KEP66421.1 - 1.6e-06 27.6 13.5 1.6e-06 27.6 9.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP66421.1 - 1.4e-05 25.0 13.1 1.4e-05 25.0 9.1 2.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP66421.1 - 4.3e-05 23.1 13.5 4.3e-05 23.1 9.4 2.6 3 0 0 3 3 3 1 zinc-RING finger domain Sina PF03145.11 KEP66421.1 - 0.0016 18.1 14.9 0.003 17.2 3.6 4.0 2 1 2 4 4 4 3 Seven in absentia protein family zf-TRAF PF02176.13 KEP66421.1 - 0.003 17.9 4.3 0.003 17.9 3.0 4.1 2 1 2 4 4 4 1 TRAF-type zinc finger zf-C3HC4_4 PF15227.1 KEP66421.1 - 0.018 14.8 10.3 0.078 12.8 7.2 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEP66421.1 - 0.13 12.0 9.5 0.13 11.9 5.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger LPAM_2 PF13627.1 KEP66421.1 - 2.3 8.0 4.8 0.59 9.8 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic lipoprotein-attachment site OTU PF02338.14 KEP66422.1 - 1.5e-17 64.3 0.1 2.4e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KEP66422.1 - 0.00021 20.7 1.6 0.02 14.2 0.0 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain Glycos_transf_2 PF00535.21 KEP66423.1 - 2.3e-20 72.9 0.0 4.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 KEP66423.1 - 1.6e-07 30.7 0.0 2.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 KEP66423.1 - 1.8e-06 27.9 0.7 7.8e-06 25.9 0.2 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 KEP66423.1 - 3.2e-06 26.5 0.1 3.2e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 KEP66423.1 - 5.8e-06 26.2 0.0 2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RAB3GAP2_N PF14655.1 KEP66425.1 - 8.6e-20 71.1 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF2A PF08662.6 KEP66426.1 - 9.9e-59 198.3 0.0 2.6e-57 193.7 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SsgA PF04686.7 KEP66426.1 - 0.051 13.2 0.0 0.19 11.4 0.0 2.0 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA Baculo_PEP_C PF04513.7 KEP66427.1 - 0.0015 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_cc2 PF10267.4 KEP66427.1 - 0.0034 16.0 0.7 0.0048 15.5 0.5 1.2 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein GOLGA2L5 PF15070.1 KEP66427.1 - 0.0068 14.9 0.9 0.0082 14.6 0.6 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 MIS13 PF08202.6 KEP66427.1 - 0.008 15.2 0.5 0.011 14.7 0.3 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family THOC7 PF05615.8 KEP66427.1 - 0.014 15.6 0.7 0.022 15.0 0.5 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 DUF4455 PF14643.1 KEP66427.1 - 0.016 13.8 0.4 0.02 13.5 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Osmo_CC PF08946.5 KEP66427.1 - 0.022 14.7 2.5 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Syntaxin PF00804.20 KEP66427.1 - 0.028 14.5 0.2 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 Syntaxin Leu_zip PF15294.1 KEP66427.1 - 0.033 13.2 1.4 0.04 13.0 1.0 1.1 1 0 0 1 1 1 0 Leucine zipper FAM70 PF14967.1 KEP66427.1 - 0.035 13.3 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 FAM70 protein Thioredoxin_2 PF13098.1 KEP66427.1 - 0.037 14.2 0.1 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain SF-assemblin PF06705.6 KEP66427.1 - 0.053 12.6 2.0 0.097 11.7 1.3 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin BAR PF03114.13 KEP66427.1 - 0.1 12.0 1.3 0.16 11.4 0.9 1.2 1 0 0 1 1 1 0 BAR domain DUF1664 PF07889.7 KEP66427.1 - 0.2 11.4 2.5 0.43 10.3 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HAUS-augmin3 PF14932.1 KEP66427.1 - 0.45 9.6 3.7 1 8.5 2.6 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 PspA_IM30 PF04012.7 KEP66427.1 - 0.83 8.9 5.3 0.33 10.2 0.4 2.0 2 0 0 2 2 2 0 PspA/IM30 family ubiquitin PF00240.18 KEP66428.1 - 1e-06 27.9 0.1 2.6e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KEP66428.1 - 2.6e-05 24.3 0.0 8.3e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 KEP66428.1 - 0.022 14.4 0.1 0.15 11.7 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.13 KEP66428.1 - 0.061 13.2 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain MxiM PF11441.3 KEP66428.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Pilot protein MxiM UN_NPL4 PF11543.3 KEP66428.1 - 0.13 12.6 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Tcp10_C PF07202.8 KEP66429.1 - 1.5e-20 73.4 0.1 2.5e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 T-complex protein 10 C-terminus 60KD_IMP PF02096.15 KEP66429.1 - 4.9 6.7 1.9 12 5.5 1.3 1.6 1 0 0 1 1 1 0 60Kd inner membrane protein MFS_1 PF07690.11 KEP66430.1 - 1e-21 77.0 37.3 1e-21 77.0 25.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 KEP66430.1 - 1.6e-06 26.5 12.3 0.013 13.5 4.2 3.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Aminotran_1_2 PF00155.16 KEP66432.1 - 8.6e-69 232.2 0.0 1.1e-68 231.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEP66432.1 - 7.2e-05 21.6 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEP66432.1 - 0.0014 17.8 0.1 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KEP66432.1 - 0.0028 15.9 0.0 0.0045 15.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TBP PF00352.16 KEP66433.1 - 1.7e-53 177.8 0.2 7.4e-29 98.9 0.0 3.1 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KEP66433.1 - 0.0034 17.4 0.0 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) Ferrochelatase PF00762.14 KEP66437.1 - 1.9e-76 257.0 0.0 1e-61 208.6 0.0 2.3 2 0 0 2 2 2 2 Ferrochelatase CbiX PF01903.12 KEP66437.1 - 0.053 13.6 0.2 3.3 7.8 0.0 3.4 4 0 0 4 4 4 0 CbiX ADK PF00406.17 KEP66438.1 - 1.2e-22 80.3 0.0 2.8e-12 46.7 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_33 PF13671.1 KEP66438.1 - 5e-09 36.1 0.2 7.8e-07 29.0 0.0 2.8 1 1 2 3 3 3 1 AAA domain AAA_18 PF13238.1 KEP66438.1 - 4.3e-08 33.5 0.0 1.7e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEP66438.1 - 1e-07 32.7 0.0 2.6e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEP66438.1 - 0.0028 16.9 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KEP66438.1 - 0.036 13.1 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KEP66438.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IF3_C PF00707.17 KEP66439.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 KEP66439.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain FKBP_C PF00254.23 KEP66440.1 - 3.7e-09 36.4 0.0 3.9e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Toxin_12 PF07740.7 KEP66441.1 - 0.61 10.6 4.9 1.1 9.8 3.4 1.3 1 0 0 1 1 1 0 Ion channel inhibitory toxin RRM_1 PF00076.17 KEP66442.1 - 3.5e-06 26.5 0.1 7.2e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66442.1 - 0.00013 21.8 0.1 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.2 KEP66443.1 - 2.8e-10 40.0 0.0 0.0002 20.9 0.0 4.0 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEP66443.1 - 0.00039 20.1 0.0 0.0051 16.4 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily TrbI PF03743.9 KEP66443.1 - 0.12 11.8 0.2 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Kinase-like PF14531.1 KEP66444.1 - 3.7e-35 121.2 0.0 6.3e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP66444.1 - 2.3e-23 82.6 0.0 1.9e-22 79.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66444.1 - 1.6e-06 27.3 0.0 3.3e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP66444.1 - 0.012 15.3 0.0 3.2 7.4 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEP66444.1 - 0.023 13.5 0.1 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KEP66444.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Dpy-30 PF05186.8 KEP66445.1 - 0.0003 20.1 0.1 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif CENP-B_dimeris PF09026.5 KEP66445.1 - 0.0065 16.6 3.3 0.0065 16.6 2.3 4.7 5 0 0 5 5 5 1 Centromere protein B dimerisation domain UPF0075 PF03702.9 KEP66445.1 - 0.069 12.0 0.4 0.12 11.2 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) SAG PF04092.8 KEP66447.1 - 7.8e-31 107.0 11.8 2.9e-17 63.2 1.0 2.1 2 0 0 2 2 2 2 SRS domain His_Phos_1 PF00300.17 KEP66448.1 - 1.5e-10 41.3 0.1 4.5e-09 36.5 0.0 2.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) BHD_1 PF10403.4 KEP66448.1 - 0.001 18.5 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 WD40 PF00400.27 KEP66449.1 - 1.6e-41 138.7 14.7 9.2e-07 28.5 0.2 11.1 11 0 0 11 11 11 8 WD domain, G-beta repeat PQQ_2 PF13360.1 KEP66449.1 - 2.3e-05 23.9 0.0 0.00044 19.7 0.0 2.6 1 1 2 3 3 3 1 PQQ-like domain PQQ_3 PF13570.1 KEP66449.1 - 3.8 7.9 9.4 12 6.2 0.0 5.8 8 1 1 9 9 9 0 PQQ-like domain WD40 PF00400.27 KEP66450.1 - 3.2e-16 58.4 6.3 2e-08 33.7 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2330 PF10092.4 KEP66450.1 - 0.052 12.4 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) DUF3504 PF12012.3 KEP66450.1 - 0.074 12.8 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) PDEase_I PF00233.14 KEP66452.1 - 8e-39 133.7 0.6 1.3e-38 133.0 0.4 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.26 KEP66452.1 - 2.7e-09 36.5 0.8 5.1e-09 35.6 0.5 1.4 1 0 0 1 1 1 1 Ion transport protein RRP7 PF12923.2 KEP66453.1 - 2.8e-17 62.9 8.2 2.1e-08 34.2 0.0 2.5 3 0 0 3 3 3 2 Ribosomal RNA-processing protein 7 (RRP7) PDCD9 PF07147.7 KEP66453.1 - 0.059 12.1 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) G-patch PF01585.18 KEP66455.1 - 0.001 18.8 2.5 0.0024 17.6 1.7 1.6 1 0 0 1 1 1 1 G-patch domain DUF3138 PF11336.3 KEP66455.1 - 0.014 13.6 4.9 0.064 11.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) BRCT PF00533.21 KEP66456.1 - 0.033 14.3 0.0 0.83 9.8 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF1319 PF07028.6 KEP66460.1 - 0.15 12.2 0.3 0.35 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) PA14 PF07691.7 KEP66462.1 - 2.2e-22 79.3 0.0 5.9e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 PA14 domain LCCL PF03815.14 KEP66462.1 - 1.4e-15 57.0 0.1 3.5e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.20 KEP66462.1 - 6.5e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain DUF1741 PF08427.5 KEP66462.1 - 0.29 10.5 0.0 0.44 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DnaJ PF00226.26 KEP66463.1 - 6.7e-27 93.0 2.5 1e-26 92.4 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEP66463.1 - 3.6e-21 74.8 0.0 5.1e-18 64.7 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEP66463.1 - 0.00054 19.9 2.2 0.00096 19.1 1.5 1.3 1 0 0 1 1 1 1 DnaJ central domain EFP_N PF08207.7 KEP66464.1 - 3.7e-16 58.7 0.1 1.2e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.6 KEP66464.1 - 6.5e-13 47.8 0.1 1.3e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.15 KEP66464.1 - 3.9e-08 32.8 0.0 8.4e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Neuroparsin PF07327.6 KEP66464.1 - 0.026 14.7 2.5 0.053 13.7 1.7 1.5 1 0 0 1 1 1 0 Neuroparsin Pkinase PF00069.20 KEP66465.1 - 5.4e-15 55.2 0.0 1.4e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 KEP66465.1 - 1.5e-07 30.6 0.0 3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KEP66465.1 - 3.7e-06 26.2 0.0 5.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KEP66465.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family AflR PF08493.5 KEP66465.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein ATP-synt_B PF00430.13 KEP66466.1 - 2.3 8.0 23.3 6.3 6.6 16.1 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) SNF2_N PF00176.18 KEP66468.1 - 9.7e-62 208.4 0.1 1.9e-61 207.4 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP66468.1 - 3.8e-17 61.9 0.0 1.4e-16 60.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KEP66468.1 - 2e-14 52.9 2.6 3.8e-08 32.8 0.0 3.2 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain HDA2-3 PF11496.3 KEP66468.1 - 5.5e-12 45.1 0.1 1.3e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF4208 PF13907.1 KEP66468.1 - 2.8e-06 27.4 0.0 2.5e-05 24.4 0.0 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4208) DEAD PF00270.24 KEP66468.1 - 0.0002 20.8 0.2 0.00059 19.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Exo_endo_phos PF03372.18 KEP66469.1 - 0.042 13.7 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RNA_pol_Rpb2_6 PF00562.23 KEP66470.1 - 1.6e-120 402.4 0.0 2.2e-120 401.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEP66470.1 - 6.5e-60 201.5 0.0 9.3e-60 201.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KEP66470.1 - 2.9e-51 173.5 0.0 5.3e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KEP66470.1 - 1.4e-30 105.3 0.1 3.2e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 KEP66470.1 - 1.2e-24 85.8 0.0 2.4e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KEP66470.1 - 1.7e-22 79.0 0.1 6e-22 77.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KEP66470.1 - 9.2e-17 60.7 3.7 3e-16 59.1 0.9 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 ELMO_CED12 PF04727.8 KEP66472.1 - 7e-20 71.2 0.6 4.9e-19 68.5 0.2 2.2 2 0 0 2 2 2 1 ELMO/CED-12 family Carb_kinase PF01256.12 KEP66474.1 - 6.1e-29 100.9 6.3 7.2e-21 74.5 0.1 4.0 2 2 1 3 3 3 3 Carbohydrate kinase Proteasome PF00227.21 KEP66475.1 - 6.3e-52 175.6 0.1 8.2e-52 175.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEP66475.1 - 7.8e-15 53.8 0.0 1.3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ras PF00071.17 KEP66476.1 - 1.6e-63 212.9 0.5 1.8e-63 212.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP66476.1 - 3.8e-20 72.5 0.0 9.5e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEP66476.1 - 4.6e-15 55.3 0.0 5.9e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEP66476.1 - 4.6e-07 29.2 0.1 6.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEP66476.1 - 1.5e-05 24.4 0.1 3.7e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEP66476.1 - 2.1e-05 24.4 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEP66476.1 - 6.5e-05 22.2 0.1 8.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KEP66476.1 - 0.008 16.3 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEP66476.1 - 0.015 14.4 0.2 0.031 13.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KEP66476.1 - 0.037 13.7 0.1 0.16 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEP66476.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 KEP66476.1 - 0.055 12.7 0.2 0.47 9.7 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DAP3 PF10236.4 KEP66476.1 - 0.14 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 KEP66476.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pex2_Pex12 PF04757.9 KEP66477.1 - 3e-23 82.4 11.6 5.1e-23 81.6 8.1 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 KEP66477.1 - 0.037 13.6 3.8 0.98 9.1 1.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 KEP66477.1 - 0.15 11.5 2.2 0.84 9.2 1.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 KEP66477.1 - 4.1 7.1 7.3 0.7 9.5 2.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP66477.1 - 6.1 6.9 8.6 0.82 9.7 2.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PIG-L PF02585.12 KEP66478.1 - 6e-24 84.9 0.0 1.1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Sdh5 PF03937.11 KEP66479.1 - 1.1e-16 60.3 0.0 1.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase PI3K_1B_p101 PF10486.4 KEP66479.1 - 0.77 7.2 6.3 0.94 6.9 4.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TPR_MLP1_2 PF07926.7 KEP66482.1 - 1.3e-06 28.1 29.7 1.3e-06 28.1 20.6 8.4 6 2 1 8 8 8 3 TPR/MLP1/MLP2-like protein GAS PF13851.1 KEP66482.1 - 0.00026 20.2 25.9 0.00026 20.2 17.9 6.8 3 2 2 7 7 7 3 Growth-arrest specific micro-tubule binding Actin PF00022.14 KEP66485.1 - 4.7e-75 252.4 0.0 1.4e-36 125.7 0.0 2.0 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KEP66485.1 - 0.0051 15.4 0.0 0.21 10.1 0.0 2.4 3 0 0 3 3 3 2 MreB/Mbl protein PilM_2 PF11104.3 KEP66485.1 - 0.2 10.4 0.0 0.38 9.5 0.0 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; DNA_pol_B PF00136.16 KEP66486.1 - 8.6e-138 459.9 1.5 1.2e-137 459.5 1.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KEP66486.1 - 9.8e-68 228.3 0.0 1.6e-67 227.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KEP66486.1 - 2.3e-22 78.7 7.9 5.1e-22 77.6 5.5 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 KEP66486.1 - 0.075 11.6 0.5 0.48 9.0 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 KEP66486.1 - 0.083 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Glu_cyclase_2 PF05096.7 KEP66488.1 - 1.3e-12 47.3 0.0 2.9e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Glutamine cyclotransferase Pkinase PF00069.20 KEP66489.1 - 1.2e-60 204.9 0.0 4.5e-59 199.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66489.1 - 2.2e-27 95.7 0.0 3.8e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP66489.1 - 5.3e-05 22.3 0.0 8.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEP66489.1 - 0.45 9.2 0.1 0.71 8.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA_2 PF07724.9 KEP66491.1 - 9.1e-53 178.6 0.0 1.3e-51 174.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEP66491.1 - 1.1e-25 90.4 0.0 1.1e-12 48.2 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEP66491.1 - 1.4e-21 76.1 0.1 6e-21 74.1 0.0 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KEP66491.1 - 5.2e-16 58.6 0.0 1.7e-10 40.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 KEP66491.1 - 3.8e-12 45.9 0.2 3.2e-08 33.3 0.0 3.2 3 0 0 3 3 2 2 Clp amino terminal domain AAA_16 PF13191.1 KEP66491.1 - 4.4e-12 46.3 13.8 4.5e-06 26.7 0.0 5.6 3 3 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KEP66491.1 - 2.4e-10 40.6 0.0 0.0021 18.1 0.0 3.9 2 2 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KEP66491.1 - 2.4e-08 33.9 2.2 0.14 11.8 0.1 4.5 2 2 2 4 4 4 3 Archaeal ATPase Sigma54_activat PF00158.21 KEP66491.1 - 5.9e-08 32.3 0.1 3.3e-05 23.4 0.0 3.1 3 1 0 3 3 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KEP66491.1 - 4.5e-07 29.8 0.0 0.017 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEP66491.1 - 8.9e-07 29.7 4.5 0.0095 16.7 0.0 3.8 2 2 0 3 3 3 2 AAA domain AAA_18 PF13238.1 KEP66491.1 - 1.3e-06 28.7 0.0 0.041 14.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KEP66491.1 - 3.6e-06 26.6 1.2 0.0048 16.3 0.0 3.8 3 1 1 4 4 4 1 AAA-like domain NTPase_1 PF03266.10 KEP66491.1 - 6.4e-05 22.7 0.5 1.9 8.1 0.0 4.4 4 0 0 4 4 4 1 NTPase RNA_helicase PF00910.17 KEP66491.1 - 7.4e-05 22.8 0.0 0.89 9.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Zeta_toxin PF06414.7 KEP66491.1 - 8.4e-05 21.7 0.0 0.018 14.1 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin IstB_IS21 PF01695.12 KEP66491.1 - 0.00013 21.4 0.0 0.21 10.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.7 KEP66491.1 - 0.00013 21.0 1.5 0.035 13.1 0.0 3.3 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEP66491.1 - 0.00024 20.7 0.7 0.12 12.1 0.0 3.2 4 0 0 4 4 2 1 Part of AAA domain NACHT PF05729.7 KEP66491.1 - 0.0003 20.4 0.0 1.1 8.8 0.0 2.8 2 0 0 2 2 2 2 NACHT domain Mg_chelatase PF01078.16 KEP66491.1 - 0.00032 19.9 0.0 0.47 9.5 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KEP66491.1 - 0.00039 19.4 0.0 0.06 12.2 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MobB PF03205.9 KEP66491.1 - 0.00046 19.9 0.0 0.29 10.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KEP66491.1 - 0.0021 18.4 0.8 5.5 7.2 1.2 3.1 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 KEP66491.1 - 0.003 17.4 0.0 1.2 9.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEP66491.1 - 0.0035 17.3 0.4 6.2 6.7 0.0 3.7 3 1 1 4 4 4 0 AAA domain DUF258 PF03193.11 KEP66491.1 - 0.0038 16.4 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_3 PF07726.6 KEP66491.1 - 0.0055 16.3 0.0 0.87 9.1 0.0 3.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KEP66491.1 - 0.01 15.2 0.7 3.8 6.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain DNA_pol3_delta2 PF13177.1 KEP66491.1 - 0.011 15.4 0.0 0.1 12.2 0.0 2.5 2 2 1 3 3 2 0 DNA polymerase III, delta subunit AAA_29 PF13555.1 KEP66491.1 - 0.014 14.9 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEP66491.1 - 0.015 15.6 0.1 4 7.7 0.0 3.1 3 0 0 3 3 2 0 ABC transporter MMR_HSR1 PF01926.18 KEP66491.1 - 0.018 14.9 0.0 1.2 9.0 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEP66491.1 - 0.027 14.0 0.1 1.4 8.3 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 KEP66491.1 - 0.086 12.4 0.0 2.5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEP66491.1 - 0.1 13.1 0.0 7.9 6.9 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein RRF PF01765.14 KEP66492.1 - 3e-25 88.5 1.2 5.3e-25 87.7 0.8 1.5 1 1 0 1 1 1 1 Ribosome recycling factor NBP1 PF08537.5 KEP66492.1 - 4.5 6.3 9.7 20 4.2 6.8 2.0 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF3094 PF11293.3 KEP66493.1 - 0.35 10.3 0.0 0.35 10.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) DUF4094 PF13334.1 KEP66493.1 - 1 9.7 4.2 0.93 9.9 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) NTP_transferase PF00483.18 KEP66494.1 - 2.4e-40 138.4 0.0 1.6e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.19 KEP66494.1 - 4e-09 35.5 5.6 2.7e-06 26.6 0.2 3.3 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KEP66494.1 - 5.9e-07 29.6 0.0 9.6e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KEP66494.1 - 7.7e-06 25.3 1.3 7.7e-06 25.3 0.9 3.7 3 2 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase Shadoo PF14999.1 KEP66494.1 - 0.015 15.1 2.4 0.03 14.1 1.6 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PDEase_I PF00233.14 KEP66495.1 - 2.6e-41 141.9 4.6 6.4e-22 78.4 0.1 3.2 3 0 0 3 3 3 3 3'5'-cyclic nucleotide phosphodiesterase DUF1186 PF06685.6 KEP66498.1 - 0.057 12.5 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) FDC-SP PF15215.1 KEP66498.1 - 0.13 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide NTP_transf_2 PF01909.18 KEP66499.1 - 0.0026 18.0 0.0 0.005 17.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Hist_deacetyl PF00850.14 KEP66500.1 - 5.3e-32 111.3 0.0 7.8e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SET PF00856.23 KEP66502.1 - 1.6e-25 90.2 0.1 1.5e-24 87.0 0.1 2.9 1 1 0 1 1 1 1 SET domain PHD PF00628.24 KEP66502.1 - 0.00025 20.6 23.5 0.00061 19.4 5.6 5.1 5 0 0 5 5 5 3 PHD-finger S-methyl_trans PF02574.11 KEP66504.1 - 1.4e-44 152.6 0.0 1.1e-16 61.0 0.0 3.2 2 1 1 3 3 3 3 Homocysteine S-methyltransferase ADK PF00406.17 KEP66505.1 - 3.8e-36 124.2 0.0 1.4e-24 86.7 0.0 2.2 1 1 0 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 KEP66505.1 - 4e-07 30.3 0.1 7.5e-06 26.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KEP66505.1 - 2e-06 27.7 0.0 6.3e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEP66505.1 - 0.0013 19.5 0.0 0.0025 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KEP66505.1 - 0.0019 17.6 0.2 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 KEP66505.1 - 0.0028 16.7 0.0 0.007 15.4 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Peptidase_M24 PF00557.19 KEP66506.1 - 1.7e-41 142.0 0.1 2.2e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 E1-E2_ATPase PF00122.15 KEP66507.1 - 9.3e-11 41.1 6.7 2.7e-09 36.4 0.0 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.21 KEP66507.1 - 2.8e-10 40.9 0.1 0.00073 20.0 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP66507.1 - 4.4e-08 33.5 0.0 0.059 13.5 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP66507.1 - 3.1e-05 23.8 0.0 0.00017 21.4 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEP66507.1 - 0.001 18.6 0.4 0.39 10.2 0.0 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Actin PF00022.14 KEP66508.1 - 2e-53 181.2 0.0 7.8e-35 120.0 0.0 2.2 2 0 0 2 2 2 2 Actin DUF2484 PF10658.4 KEP66510.1 - 0.1 12.7 1.6 0.36 10.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) ER_lumen_recept PF00810.13 KEP66510.1 - 2.2 8.7 12.5 8.6 6.8 0.6 4.0 4 1 0 4 4 4 0 ER lumen protein retaining receptor EF-hand_6 PF13405.1 KEP66512.1 - 0.00094 18.8 0.0 0.012 15.4 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KEP66512.1 - 0.0015 18.6 0.1 0.0042 17.1 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KEP66512.1 - 0.0084 15.3 0.0 0.23 10.8 0.0 2.8 2 0 0 2 2 2 1 EF hand Rad50_zn_hook PF04423.9 KEP66512.1 - 0.1 12.0 0.3 0.49 9.8 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif Pyr_redox_2 PF07992.9 KEP66514.1 - 0.011 15.5 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PIH1 PF08190.7 KEP66515.1 - 2.1e-08 33.9 26.7 0.00038 20.0 0.2 5.7 3 2 2 5 5 5 4 pre-RNA processing PIH1/Nop17 THF_DHG_CYH_C PF02882.14 KEP66516.1 - 7.5e-42 142.1 1.4 3.7e-31 107.3 0.1 2.2 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KEP66516.1 - 1.1e-07 31.9 0.0 4.7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SET PF00856.23 KEP66518.1 - 0.36 11.1 0.0 0.36 11.1 0.0 5.3 5 2 0 5 5 5 0 SET domain PsbI PF02532.9 KEP66520.1 - 0.26 10.9 0.1 0.26 10.9 0.1 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) WD40 PF00400.27 KEP66521.1 - 7.5e-18 63.6 13.9 1.5e-06 27.8 0.7 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat HHH PF00633.18 KEP66523.1 - 0.048 13.3 2.3 1.4 8.7 0.0 3.6 4 0 0 4 4 4 0 Helix-hairpin-helix motif MFS_1 PF07690.11 KEP66524.1 - 4.1e-13 48.7 50.7 4.2e-12 45.4 23.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Synaptobrevin PF00957.16 KEP66525.1 - 7.1e-21 73.6 2.8 9.8e-21 73.1 1.9 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEP66525.1 - 0.0015 17.9 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain CDP-OH_P_transf PF01066.16 KEP66526.1 - 1.6e-19 70.0 4.3 1.6e-19 70.0 3.0 2.9 4 0 0 4 4 4 1 CDP-alcohol phosphatidyltransferase Hydrolase_4 PF12146.3 KEP66527.1 - 8.4e-09 35.1 0.4 1.6e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_6 PF12697.2 KEP66527.1 - 9.8e-09 35.4 7.3 3e-07 30.5 1.8 3.2 2 1 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP66527.1 - 1.2e-07 31.5 0.4 1.8e-06 27.7 0.3 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Prefoldin PF02996.12 KEP66528.1 - 4.8e-22 77.8 2.5 6.9e-22 77.3 1.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Rootletin PF15035.1 KEP66528.1 - 0.044 13.7 2.2 0.061 13.2 1.6 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Muted PF14942.1 KEP66528.1 - 0.14 11.9 0.2 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Acyl-CoA_dh_2 PF08028.6 KEP66528.1 - 0.19 11.9 4.9 2.2 8.5 0.1 2.2 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Aldedh PF00171.17 KEP66529.1 - 5.8e-139 463.3 5.4 1.5e-106 356.5 0.8 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Myosin_head PF00063.16 KEP66530.1 - 3.8e-117 392.1 0.0 1.4e-94 317.5 0.0 2.5 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.1 KEP66530.1 - 0.0071 16.4 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEP66530.1 - 0.067 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 BTV_NS2 PF04514.7 KEP66530.1 - 2.1 7.1 2.0 4.7 5.9 1.4 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SCO1-SenC PF02630.9 KEP66532.1 - 1.1e-46 158.6 0.0 1.7e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC DUF3393 PF11873.3 KEP66534.1 - 0.14 11.6 0.3 0.31 10.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) MMR_HSR1 PF01926.18 KEP66535.1 - 6.7e-17 61.5 0.0 2.4e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP66535.1 - 0.00053 19.3 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEP66535.1 - 0.0028 17.4 0.0 0.13 12.0 0.1 2.8 1 1 0 2 2 2 1 Dynamin family DUF258 PF03193.11 KEP66535.1 - 0.031 13.4 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KEP66535.1 - 0.039 13.3 0.0 0.23 10.8 0.0 2.2 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Inhibitor_I42 PF09394.5 KEP66536.1 - 0.097 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 DUF1353 PF07087.6 KEP66536.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) MIF4G PF02854.14 KEP66539.1 - 2.4e-28 98.9 0.4 3.8e-28 98.3 0.3 1.3 1 0 0 1 1 1 1 MIF4G domain Aurora-A_bind PF09041.5 KEP66539.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Aurora-A binding RNA_polI_A34 PF08208.6 KEP66539.1 - 5.6 6.5 31.7 2 8.0 2.3 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Ras PF00071.17 KEP66540.1 - 8.6e-58 194.2 0.1 9.9e-58 194.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEP66540.1 - 9e-22 77.8 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEP66540.1 - 3.5e-15 55.6 0.0 4.5e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEP66540.1 - 3.5e-07 29.8 0.0 1.4e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEP66540.1 - 3.3e-05 23.8 0.0 5.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEP66540.1 - 0.00041 19.9 0.0 0.075 12.5 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 KEP66540.1 - 0.0012 18.0 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KEP66540.1 - 0.0086 16.2 0.0 0.038 14.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 KEP66540.1 - 0.025 13.3 0.0 0.82 8.3 0.0 2.1 2 0 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 KEP66540.1 - 0.037 13.3 0.0 0.33 10.2 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 KEP66540.1 - 0.039 13.5 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KEP66540.1 - 0.083 12.8 0.1 0.099 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 KEP66540.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.14 KEP66540.1 - 0.22 10.9 0.9 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 KEP66541.1 - 1.1 7.8 3.4 2.3 6.8 2.4 1.4 1 0 0 1 1 1 0 G-protein alpha subunit CS PF04969.11 KEP66542.1 - 6.4e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 CS domain PIH1 PF08190.7 KEP66542.1 - 0.00035 20.1 0.0 0.00081 18.9 0.0 1.6 2 0 0 2 2 2 1 pre-RNA processing PIH1/Nop17 CDC37_N PF03234.9 KEP66542.1 - 0.11 12.7 0.5 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding AKAP2_C PF15304.1 KEP66542.1 - 0.22 11.1 8.4 0.61 9.6 5.8 1.8 1 1 0 1 1 1 0 A-kinase anchor protein 2 C-terminus AAA_21 PF13304.1 KEP66543.1 - 8.2 6.2 6.6 13 5.6 4.6 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KEP66545.1 - 1.4e-08 34.4 0.0 6e-08 32.5 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KEP66545.1 - 1e-07 32.2 0.0 0.011 15.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KEP66545.1 - 3e-07 29.8 0.0 0.00099 18.2 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.14 KEP66545.1 - 1.5e-05 24.3 0.0 1.5e-05 24.3 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 KEP66545.1 - 0.02 15.2 0.0 0.02 15.2 0.0 7.3 6 4 0 6 6 6 0 ABC transporter AAA_29 PF13555.1 KEP66545.1 - 0.025 14.1 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.1 KEP66545.1 - 0.057 11.8 0.0 0.057 11.8 0.0 7.5 4 2 2 7 7 7 0 AAA domain AAA_19 PF13245.1 KEP66545.1 - 0.062 13.0 2.0 1.6 8.5 0.1 3.5 2 0 0 2 2 2 0 Part of AAA domain SNARE_assoc PF09335.6 KEP66547.1 - 0.14 12.3 0.9 0.16 12.1 0.1 1.5 2 0 0 2 2 2 0 SNARE associated Golgi protein NOT2_3_5 PF04153.13 KEP66549.1 - 3.8e-20 72.1 0.0 3.8e-20 72.1 0.0 2.7 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Med15 PF09606.5 KEP66549.1 - 0.045 11.9 18.3 0.071 11.2 12.7 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-CCCH PF00642.19 KEP66550.1 - 2.2e-08 33.5 15.6 0.0011 18.6 1.9 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEP66550.1 - 0.00023 21.0 11.4 1 9.4 0.6 3.8 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type Sugar_tr PF00083.19 KEP66551.1 - 9.7e-68 228.7 24.6 1.2e-67 228.4 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEP66551.1 - 3.5e-21 75.3 34.8 8.7e-21 74.0 23.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEP66551.1 - 0.0003 19.1 2.6 0.00044 18.5 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M76 PF09768.4 KEP66552.1 - 8.3e-33 113.2 0.0 1.5e-23 83.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase M76 family NAC PF01849.13 KEP66554.1 - 2.4e-18 65.4 0.0 4.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 NAC domain COQ9 PF08511.6 KEP66554.1 - 0.098 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 COQ9 PDEase_I PF00233.14 KEP66555.1 - 5.6e-55 186.6 0.5 8.3e-55 186.1 0.3 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Med3 PF11593.3 KEP66555.1 - 2.8 7.0 4.2 4.9 6.2 2.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ArfGap PF01412.13 KEP66556.1 - 0.02 14.6 0.3 0.038 13.7 0.2 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf SUI1 PF01253.17 KEP66557.1 - 2.6e-19 68.7 0.2 4.7e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Dishevelled PF02377.10 KEP66557.1 - 0.036 14.2 3.3 0.11 12.7 2.3 1.8 1 0 0 1 1 1 0 Dishevelled specific domain Pantoate_transf PF02548.10 KEP66558.1 - 1.8e-78 263.3 1.0 2.7e-78 262.7 0.7 1.3 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.6 KEP66558.1 - 3.9e-37 127.0 0.0 1e-36 125.6 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KEP66558.1 - 1.8e-16 59.8 0.0 2.8e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA PEP_mutase PF13714.1 KEP66558.1 - 0.00013 21.3 0.0 0.00034 19.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ribosomal_S9 PF00380.14 KEP66558.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S9/S16 TB2_DP1_HVA22 PF03134.14 KEP66559.1 - 3.7e-34 116.3 3.8 5.4e-34 115.8 2.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2228 PF10228.4 KEP66560.1 - 1e-26 94.0 0.0 4.9e-19 68.8 0.0 2.4 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2228) DUF974 PF06159.8 KEP66561.1 - 2.7e-35 122.0 0.0 3.6e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.2 KEP66561.1 - 0.00047 19.5 0.1 0.083 12.1 0.0 3.1 3 1 0 3 3 3 1 TRAPP trafficking subunit Trs65 Gryzun PF07919.7 KEP66561.1 - 0.0024 16.2 0.0 0.029 12.7 0.0 2.0 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi SPOUT_MTase PF02590.12 KEP66561.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Peptidase_M16 PF00675.15 KEP66562.1 - 3.3e-43 147.0 0.3 1.2e-40 138.7 0.0 3.0 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEP66562.1 - 3.2e-27 95.3 0.0 6.9e-16 58.4 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Na_sulph_symp PF00939.14 KEP66563.1 - 1.6e-46 159.1 12.1 1e-28 100.5 0.7 2.5 2 1 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KEP66563.1 - 1.1e-11 44.0 34.3 2.8e-06 26.1 5.8 3.2 3 0 0 3 3 3 3 Citrate transporter tRNA-synt_2b PF00587.20 KEP66564.1 - 6.6e-58 195.1 0.0 3.9e-57 192.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEP66564.1 - 8e-22 76.9 0.1 8e-21 73.7 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.15 KEP66564.1 - 2.5e-05 23.8 0.9 7e-05 22.4 0.6 1.8 1 0 0 1 1 1 1 WHEP-TRS domain Spc7 PF08317.6 KEP66564.1 - 0.018 13.7 0.6 0.034 12.8 0.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.6 KEP66564.1 - 0.021 13.3 1.2 0.034 12.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Med15_fungi PF05397.7 KEP66564.1 - 0.065 13.2 0.9 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 15 Atg14 PF10186.4 KEP66564.1 - 0.14 11.0 2.0 0.1 11.5 0.2 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 KEP66564.1 - 2.3 7.7 5.1 2.6 7.5 0.2 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Acyltransferase PF01553.16 KEP66565.1 - 3.5e-13 49.1 0.1 2e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 Acyltransferase TRAP-gamma PF07074.7 KEP66565.1 - 1.5 8.3 3.2 1.2 8.6 0.7 1.9 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Ribosomal_L4 PF00573.17 KEP66566.1 - 0.13 11.6 1.4 0.17 11.2 1.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family ATP-synt_ab PF00006.20 KEP66567.1 - 1.4e-109 364.6 0.0 1.9e-109 364.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEP66567.1 - 4e-24 85.2 0.1 7.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEP66567.1 - 7.9e-14 51.6 0.2 2e-13 50.3 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 KEP66567.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FYVE PF01363.16 KEP66568.1 - 2e-12 46.8 6.1 2e-12 46.8 4.2 2.9 2 0 0 2 2 2 1 FYVE zinc finger Cpn60_TCP1 PF00118.19 KEP66568.1 - 5.8e-06 25.1 0.0 2e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family MIP-T3 PF10243.4 KEP66568.1 - 4.8e-05 22.0 9.9 4.8e-05 22.0 6.9 6.4 5 1 1 6 6 6 1 Microtubule-binding protein MIP-T3 PIP5K PF01504.13 KEP66569.1 - 2.9e-35 121.5 0.0 9.5e-35 119.9 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Imm27 PF15573.1 KEP66569.1 - 1.9 7.5 0.0 4.3 6.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 27 BRO1 PF03097.13 KEP66570.1 - 2.5e-33 115.3 0.0 6.2e-33 114.0 0.0 1.7 1 1 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KEP66570.1 - 3.5e-14 52.4 9.3 1.7e-12 46.9 6.4 2.4 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV HsbA PF12296.3 KEP66570.1 - 0.18 11.6 0.1 0.48 10.2 0.0 1.7 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Lge1 PF11488.3 KEP66570.1 - 0.4 10.8 5.0 0.12 12.5 0.5 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DEAD PF00270.24 KEP66571.1 - 3e-31 108.1 0.0 6e-22 77.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP66571.1 - 4.4e-15 55.2 0.0 1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 KEP66572.1 - 1.2e-33 116.3 0.0 1.8e-16 60.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66572.1 - 1.3e-14 53.9 0.0 5.4e-08 32.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 KEP66572.1 - 2.7e-06 27.3 0.1 2.7e-06 27.3 0.1 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP66572.1 - 5.5e-05 22.2 0.0 0.0093 14.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Clathrin PF00637.15 KEP66573.1 - 2.1e-09 37.1 1.6 0.04 13.5 0.0 4.4 3 1 1 4 4 4 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 KEP66573.1 - 1.9e-08 33.5 0.4 9.7e-05 21.3 0.1 4.7 5 0 0 5 5 5 1 Coatomer WD associated region TPR_7 PF13176.1 KEP66573.1 - 7.1e-06 25.4 13.0 0.028 14.1 0.1 7.3 5 2 3 8 8 8 1 Tetratricopeptide repeat PD40 PF07676.7 KEP66573.1 - 0.00066 19.2 0.0 0.23 11.1 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40 PF00400.27 KEP66573.1 - 0.0011 18.7 4.8 20 5.2 0.0 5.9 6 0 0 6 6 6 0 WD domain, G-beta repeat TPR_14 PF13428.1 KEP66573.1 - 0.0038 17.7 16.0 1.7 9.5 0.2 7.3 5 2 1 7 7 7 1 Tetratricopeptide repeat HOOK PF05622.7 KEP66573.1 - 0.0083 13.9 0.1 0.016 13.0 0.1 1.4 1 0 0 1 1 1 1 HOOK protein Inh PF02974.9 KEP66573.1 - 0.0099 15.4 0.1 8.1 6.0 0.1 3.7 2 1 0 3 3 3 1 Protease inhibitor Inh IKI3 PF04762.7 KEP66573.1 - 0.013 13.3 0.0 0.029 12.2 0.0 1.5 1 0 0 1 1 1 0 IKI3 family TPR_1 PF00515.23 KEP66573.1 - 0.024 14.2 4.3 0.56 9.9 0.0 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat eIF2A PF08662.6 KEP66573.1 - 0.031 13.9 0.0 0.37 10.4 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A TPR_11 PF13414.1 KEP66573.1 - 0.076 12.6 4.1 0.75 9.4 0.0 4.0 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 KEP66573.1 - 0.13 12.2 0.1 0.13 12.2 0.1 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP66573.1 - 0.85 10.2 0.0 0.85 10.2 0.0 4.2 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP66573.1 - 4.9 7.1 14.7 0.95 9.4 0.3 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF829 PF05705.9 KEP66575.1 - 0.0017 18.1 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Syja_N PF02383.13 KEP66576.1 - 3.8e-51 173.7 0.0 1e-47 162.4 0.0 3.0 2 1 0 2 2 2 2 SacI homology domain TFIIA PF03153.8 KEP66577.1 - 0.0016 18.4 24.2 0.0016 18.4 16.8 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-CCCH PF00642.19 KEP66578.1 - 5.3e-06 25.9 4.5 1.2e-05 24.8 3.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 KEP66578.1 - 5.2e-05 22.9 2.7 0.093 12.6 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-CCCH_2 PF14608.1 KEP66578.1 - 0.07 13.1 2.2 0.19 11.8 1.5 1.8 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DnaJ PF00226.26 KEP66579.1 - 2.7e-21 75.0 2.7 6.6e-21 73.8 1.9 1.7 1 0 0 1 1 1 1 DnaJ domain ABC_transp_aux PF09822.4 KEP66582.1 - 1.4e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Peptidase_C97 PF05903.9 KEP66583.1 - 1.5e-31 109.1 0.0 2.2e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DEAD PF00270.24 KEP66584.1 - 6.6e-41 139.6 0.0 3.2e-40 137.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP66584.1 - 5.3e-29 99.8 0.2 1.5e-28 98.4 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KEP66584.1 - 0.00081 19.0 0.0 0.0038 16.9 0.0 2.0 1 1 1 2 2 2 1 Part of AAA domain ResIII PF04851.10 KEP66584.1 - 0.031 14.0 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Peptidase_C5 PF00770.13 KEP66584.1 - 0.035 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease AAA_22 PF13401.1 KEP66584.1 - 0.035 14.2 0.2 0.22 11.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEP66584.1 - 0.086 12.4 0.0 0.95 9.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain PK PF00224.16 KEP66585.1 - 1.5e-143 477.6 0.7 2.3e-143 477.0 0.5 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KEP66585.1 - 4.2e-30 103.6 4.0 1.9e-29 101.5 2.8 2.2 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KEP66585.1 - 0.00022 20.1 0.9 0.00079 18.3 0.0 2.2 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Radial_spoke_3 PF06098.6 KEP66586.1 - 2 7.3 7.3 1.7 7.5 3.5 1.7 2 0 0 2 2 2 0 Radial spoke protein 3 Helicase_C PF00271.26 KEP66587.1 - 7.3e-11 41.7 0.0 1.9e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP66587.1 - 3.3e-09 36.4 0.0 7.5e-07 28.7 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Mitofilin PF09731.4 KEP66588.1 - 1.8 7.1 19.4 2.2 6.8 13.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein KBP_C PF12309.3 KEP66590.1 - 1.3e-44 152.7 4.7 1.3e-44 152.7 3.2 2.2 2 0 0 2 2 2 1 KIF-1 binding protein C terminal Pkinase PF00069.20 KEP66591.1 - 1.7e-06 27.3 0.0 0.17 11.0 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66591.1 - 0.0013 17.9 0.0 0.16 11.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase MFS_1 PF07690.11 KEP66592.1 - 3.1e-31 108.3 13.4 2.7e-21 75.6 0.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KEP66592.1 - 1e-23 83.6 0.0 1.1e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 KEP66592.1 - 4.2e-13 48.2 1.0 0.0027 15.8 0.0 4.2 3 1 0 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MotA_ExbB PF01618.11 KEP66592.1 - 0.95 9.0 0.0 2.2 7.9 0.0 1.6 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF2149 PF09919.4 KEP66592.1 - 1.2 9.2 0.0 6.4 6.9 0.0 2.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF1510 PF07423.6 KEP66597.1 - 0.022 14.1 0.1 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) VIT1 PF01988.14 KEP66597.1 - 3.6 7.0 16.7 2.9 7.3 9.5 2.5 1 1 1 2 2 2 0 VIT family RRM_1 PF00076.17 KEP66599.1 - 4.1e-53 176.9 0.5 1.7e-17 62.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66599.1 - 5.7e-40 135.1 1.3 2.8e-12 46.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66599.1 - 7.4e-32 108.9 2.1 1.6e-10 40.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 KEP66599.1 - 2.2e-09 36.9 5.6 3.9e-09 36.1 3.9 1.4 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.6 KEP66599.1 - 0.00023 21.0 0.0 0.0026 17.7 0.0 2.5 3 0 0 3 3 3 1 RNA binding domain Pkinase PF00069.20 KEP66600.1 - 1.2e-54 185.1 0.0 4.4e-54 183.3 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66600.1 - 2.2e-29 102.3 0.0 5.4e-23 81.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP66600.1 - 3e-07 29.7 0.0 7.5e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KEP66600.1 - 0.00017 20.9 0.0 0.00042 19.7 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KEP66600.1 - 0.01 15.5 0.1 0.01 15.5 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KEP66600.1 - 0.025 13.6 0.1 0.044 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KEP66600.1 - 0.042 12.6 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 cEGF PF12662.2 KEP66602.1 - 1.5 8.5 18.5 0.44 10.2 0.1 5.6 6 0 0 6 6 6 0 Complement Clr-like EGF-like WD40 PF00400.27 KEP66604.1 - 5.7e-21 73.5 7.2 5.4e-06 26.0 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF1979 PF09322.5 KEP66604.1 - 0.0059 16.2 0.1 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1979) Peptidase_C15 PF01470.12 KEP66607.1 - 1.4e-18 67.4 0.0 2e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Pyroglutamyl peptidase Chromo PF00385.19 KEP66608.1 - 5.8e-09 35.5 1.3 2.2e-08 33.6 0.9 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Sporozoite_P67 PF05642.6 KEP66608.1 - 1.7 6.3 8.8 3.8 5.2 6.1 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VID27 PF08553.5 KEP66608.1 - 8.6 4.4 12.9 15 3.6 9.0 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 KEP66608.1 - 8.9 5.2 12.0 28 3.6 8.3 1.8 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DEAD PF00270.24 KEP66610.1 - 3e-38 130.9 0.0 6.8e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP66610.1 - 4.1e-17 61.8 0.2 8.1e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP66610.1 - 6.4e-08 32.6 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KEP66610.1 - 1.1e-05 25.1 0.2 5.3e-05 22.8 0.1 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEP66610.1 - 0.0031 17.6 0.1 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain Tme5_EGF_like PF09064.5 KEP66611.1 - 0.042 13.4 36.3 3.9 7.1 0.4 8.2 7 2 0 7 7 7 0 Thrombomodulin like fifth domain, EGF-like TRAPPC9-Trs120 PF08626.6 KEP66613.1 - 1.6e-17 62.2 0.1 1.2e-07 29.5 0.0 3.7 4 0 0 4 4 4 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit FixG_C PF11614.3 KEP66613.1 - 1.6 8.8 0.1 2.8 8.0 0.0 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Glyco_tran_28_C PF04101.11 KEP66614.1 - 2.2e-15 56.7 0.0 2.2e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain WD40 PF00400.27 KEP66615.1 - 0.00018 21.2 2.4 0.74 9.8 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-RING_UBOX PF13445.1 KEP66616.1 - 4e-06 26.4 0.1 1.5e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger FAT PF02259.18 KEP66617.1 - 2.9e-19 69.2 0.1 9.5e-19 67.5 0.1 1.8 1 1 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KEP66617.1 - 2.7e-12 46.6 0.2 6.1e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase XRN_N PF03159.13 KEP66617.1 - 1.6 8.1 0.0 3.9 6.8 0.0 1.6 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus ParcG PF10274.4 KEP66617.1 - 8.3 6.2 0.0 23 4.8 0.0 1.6 1 0 0 1 1 1 0 Parkin co-regulated protein RRM_1 PF00076.17 KEP66618.1 - 1.7e-12 46.7 0.0 0.00013 21.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66618.1 - 3.4e-09 36.5 0.0 0.012 15.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66618.1 - 0.00013 21.7 0.0 0.0049 16.6 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3932 PF13068.1 KEP66618.1 - 0.081 13.0 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) gag-asp_proteas PF13975.1 KEP66619.1 - 0.0053 16.5 0.1 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KEP66619.1 - 0.0086 16.5 0.1 0.067 13.6 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 KEP66619.1 - 0.015 15.1 0.0 0.087 12.7 0.0 2.2 3 0 0 3 3 3 0 Retroviral aspartyl protease DUF4460 PF14687.1 KEP66620.1 - 6.9e-10 38.6 0.0 6.2e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 KEP66620.1 - 0.22 10.8 0.0 0.83 8.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) XPG_N PF00752.12 KEP66622.1 - 1.1e-25 89.8 0.0 3.1e-25 88.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KEP66622.1 - 2e-25 88.6 0.0 4.9e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region zf-CCCH PF00642.19 KEP66623.1 - 5.5e-22 76.9 44.0 3e-07 29.9 1.8 5.8 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEP66623.1 - 2.4e-08 33.6 40.3 0.00044 20.1 2.3 5.0 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type FYRC PF05965.9 KEP66624.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus Rhomboid PF01694.17 KEP66625.1 - 2.5e-28 98.9 12.1 5.9e-28 97.7 8.4 1.6 1 0 0 1 1 1 1 Rhomboid family DNA_pol_E_B PF04042.11 KEP66626.1 - 1.1e-13 50.9 0.3 2e-13 50.0 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Kinocilin PF15033.1 KEP66627.1 - 2.2 7.8 7.8 2.7 7.5 0.2 2.9 2 1 0 3 3 3 0 Kinocilin protein DUF155 PF02582.9 KEP66629.1 - 4.7e-50 169.8 0.0 8e-50 169.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BING4CT PF08149.6 KEP66630.1 - 1.2e-32 111.2 0.0 4.6e-31 106.1 0.0 2.6 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 KEP66630.1 - 4.5e-07 29.5 1.0 0.00044 20.0 0.1 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat AAA_2 PF07724.9 KEP66631.1 - 4e-51 173.3 0.0 3.5e-47 160.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEP66631.1 - 1e-23 83.9 1.1 2.3e-13 50.4 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEP66631.1 - 9.9e-22 76.6 0.0 5.4e-21 74.2 0.0 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 KEP66631.1 - 3.6e-18 65.2 0.5 1.5e-11 43.9 0.2 2.9 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 KEP66631.1 - 2.9e-15 56.2 0.2 1.8e-09 37.4 0.0 3.8 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEP66631.1 - 6.8e-11 42.4 9.4 0.00025 21.0 0.0 5.3 4 2 1 6 6 6 3 AAA ATPase domain AAA_22 PF13401.1 KEP66631.1 - 7.9e-10 38.9 0.5 0.0015 18.6 0.0 4.4 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.12 KEP66631.1 - 2e-09 37.1 0.1 0.0026 17.2 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 KEP66631.1 - 3.3e-08 33.5 3.0 0.032 13.9 0.0 4.1 3 1 0 4 4 3 2 Archaeal ATPase AAA_18 PF13238.1 KEP66631.1 - 8.2e-08 32.6 0.0 0.016 15.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEP66631.1 - 1.7e-07 32.0 2.7 0.0046 17.7 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KEP66631.1 - 2.2e-07 30.8 0.0 0.024 14.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KEP66631.1 - 3.3e-07 29.9 0.0 0.00092 18.7 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 KEP66631.1 - 6.1e-05 22.7 0.0 0.0021 17.7 0.0 2.9 3 0 0 3 3 3 1 DNA polymerase III, delta subunit RNA_helicase PF00910.17 KEP66631.1 - 7.1e-05 22.9 0.0 0.097 12.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 KEP66631.1 - 8.8e-05 22.2 0.2 0.17 11.4 0.0 3.2 3 1 0 3 3 3 2 NACHT domain AAA_24 PF13479.1 KEP66631.1 - 0.00043 19.9 0.3 0.75 9.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.22 KEP66631.1 - 0.00065 20.0 0.7 0.1 12.9 0.0 3.6 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.1 KEP66631.1 - 0.00083 19.0 0.0 0.87 9.3 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 KEP66631.1 - 0.00084 18.5 0.1 4.6 6.3 0.0 3.4 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEP66631.1 - 0.001 19.0 0.8 0.59 10.0 0.0 3.2 3 1 1 4 4 2 1 AAA domain AAA_25 PF13481.1 KEP66631.1 - 0.0016 17.8 0.0 1.9 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KEP66631.1 - 0.002 17.2 0.4 0.19 10.7 0.0 3.1 3 1 0 3 3 3 1 Zeta toxin RuvB_N PF05496.7 KEP66631.1 - 0.0046 16.0 3.3 2.4 7.1 0.0 3.6 3 1 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 KEP66631.1 - 0.0051 16.0 0.0 0.87 8.7 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 KEP66631.1 - 0.0067 16.1 0.0 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KEP66631.1 - 0.0084 15.5 0.0 0.38 10.1 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain NTPase_1 PF03266.10 KEP66631.1 - 0.013 15.2 0.0 15 5.2 0.0 3.3 3 0 0 3 3 3 0 NTPase V_ATPase_I PF01496.14 KEP66631.1 - 0.016 13.1 6.0 0.024 12.5 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_33 PF13671.1 KEP66631.1 - 0.019 14.8 0.0 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KEP66631.1 - 0.025 14.2 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 KEP66631.1 - 0.033 14.0 2.5 2.4 7.9 0.0 4.0 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit Miro PF08477.8 KEP66631.1 - 0.057 13.9 0.4 16 6.0 0.0 3.4 3 0 0 3 3 2 0 Miro-like protein AAA_3 PF07726.6 KEP66631.1 - 0.074 12.6 0.0 49 3.5 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KEP66631.1 - 0.085 12.8 0.0 27 4.7 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase Prominin PF05478.6 KEP66631.1 - 0.096 10.2 1.9 0.15 9.5 1.3 1.2 1 0 0 1 1 1 0 Prominin Torsin PF06309.6 KEP66631.1 - 0.14 12.0 0.0 0.54 10.1 0.0 1.9 2 0 0 2 2 1 0 Torsin DUF3373 PF11853.3 KEP66631.1 - 2 6.8 4.1 3.5 6.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) AAA_23 PF13476.1 KEP66631.1 - 8.3 6.6 20.8 30 4.8 0.0 3.7 2 1 0 2 2 1 0 AAA domain Mito_fiss_reg PF05308.6 KEP66633.1 - 0.072 12.4 0.6 0.096 12.0 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator ATP1G1_PLM_MAT8 PF02038.11 KEP66633.1 - 0.14 11.1 0.6 0.26 10.3 0.1 1.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family GWT1 PF06423.7 KEP66633.1 - 1.8 8.6 8.1 10 6.2 1.4 2.1 1 1 1 2 2 2 0 GWT1 Img2 PF05046.9 KEP66635.1 - 5.5e-15 55.3 0.0 9.3e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 KEP66635.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 1 0 1 1 1 0 Translation initiation factor SUI1 OTU PF02338.14 KEP66636.1 - 0.00014 22.4 0.0 0.001 19.6 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease RFPL3_antisense PF10489.4 KEP66636.1 - 0.0042 16.8 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Ret finger protein-like 3 antisense GTP_EFTU PF00009.22 KEP66638.1 - 8.6e-43 145.9 0.0 2.1e-42 144.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KEP66638.1 - 1.9e-13 50.0 0.0 3.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KEP66638.1 - 3.7e-07 29.8 0.0 8.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KEP66638.1 - 0.0002 20.9 0.0 0.00043 19.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV HTH_16 PF12645.2 KEP66638.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Miro PF08477.8 KEP66638.1 - 0.31 11.5 0.0 46 4.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein YIF1 PF03878.10 KEP66639.1 - 1e-29 103.4 1.9 1.9e-26 92.6 0.6 2.3 2 1 0 2 2 2 2 YIF1 Glutaredoxin PF00462.19 KEP66640.1 - 5.3e-12 45.5 0.0 8.7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Cmc1 PF08583.5 KEP66641.1 - 3.5e-09 36.3 8.7 7.5e-09 35.2 6.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KEP66641.1 - 0.0023 17.7 4.7 0.005 16.7 3.2 1.6 1 0 0 1 1 1 1 CHCH domain Clathrin_lg_ch PF01086.12 KEP66641.1 - 0.039 13.8 0.5 0.047 13.5 0.3 1.2 1 0 0 1 1 1 0 Clathrin light chain RdgC PF04381.7 KEP66641.1 - 0.14 11.0 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC RRM_1 PF00076.17 KEP66642.1 - 6e-22 77.0 0.0 8.4e-22 76.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66642.1 - 1.5e-17 63.3 0.0 2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66642.1 - 1.8e-13 50.0 0.0 2.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEP66642.1 - 0.0017 18.1 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.3 KEP66642.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Zip PF02535.17 KEP66643.1 - 0.049 12.6 1.2 0.068 12.1 0.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF948 PF06103.6 KEP66643.1 - 0.082 12.7 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SelP_N PF04592.9 KEP66643.1 - 1.1 8.6 7.2 1.6 8.0 5.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIE-A_C-term PF11521.3 KEP66643.1 - 1.7 8.6 9.0 6.2 6.8 0.0 2.7 2 1 1 3 3 3 0 C-terminal general transcription factor TFIIE alpha DSPc PF00782.15 KEP66644.1 - 6.1e-20 71.1 0.2 2.6e-17 62.6 0.1 3.2 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEP66644.1 - 0.0071 15.7 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RUN PF02759.14 KEP66644.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 RUN domain Apt1 PF10351.4 KEP66645.1 - 0.0011 17.9 0.0 0.004 16.0 0.0 2.0 1 0 0 1 1 1 1 Golgi-body localisation protein domain IF2_N PF04760.10 KEP66646.1 - 0.11 12.1 0.5 7.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region CEP19 PF14933.1 KEP66646.1 - 0.11 12.7 0.5 0.17 12.1 0.3 1.2 1 0 0 1 1 1 0 CEP19-like protein RskA PF10099.4 KEP66647.1 - 0.97 9.1 4.3 0.71 9.5 0.7 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3814 PF12769.2 KEP66648.1 - 0.087 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) CK_II_beta PF01214.13 KEP66649.1 - 8e-62 208.0 0.0 1e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Sof1 PF04158.9 KEP66649.1 - 0.09 12.8 0.3 0.09 12.8 0.2 1.7 2 0 0 2 2 2 0 Sof1-like domain TrbC_Ftype PF09673.5 KEP66649.1 - 0.11 12.0 0.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein PsbQ PF05757.6 KEP66649.1 - 4.1 6.7 6.9 2.2 7.6 3.2 1.6 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Solute_trans_a PF03619.11 KEP66650.1 - 1.7e-10 40.6 0.3 4.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Organic solute transporter Ostalpha YafO_toxin PF13957.1 KEP66652.1 - 7e-05 22.6 0.1 0.24 11.2 0.0 2.4 2 0 0 2 2 2 2 Toxin YafO, type II toxin-antitoxin system MT-A70 PF05063.9 KEP66654.1 - 5.9e-48 162.7 0.6 5.8e-23 81.3 0.1 2.2 1 1 1 2 2 2 2 MT-A70 Enolase_C PF00113.17 KEP66655.1 - 4.3e-149 495.3 0.2 5.3e-149 495.0 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KEP66655.1 - 2.2e-56 189.4 0.0 5.8e-56 188.0 0.0 1.7 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.6 KEP66655.1 - 1.3e-05 24.2 0.1 2.5e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 KEP66655.1 - 0.0011 18.8 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like Enolase_C PF00113.17 KEP66656.1 - 5.5e-144 478.6 0.1 6.6e-144 478.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KEP66656.1 - 1.2e-54 183.7 0.0 1.9e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 KEP66656.1 - 0.00022 20.2 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 KEP66656.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like GFO_IDH_MocA PF01408.17 KEP66657.1 - 6.7e-08 33.0 0.0 1.9e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_11 PF13414.1 KEP66657.1 - 9.6e-08 31.5 0.0 2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 KEP66657.1 - 2.8e-07 29.8 0.1 3.4e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEP66657.1 - 1.5e-06 28.3 0.0 0.0062 17.0 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP66657.1 - 1.2e-05 24.8 0.0 0.00078 19.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP66657.1 - 1.3e-05 24.6 0.1 0.39 10.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP66657.1 - 6.6e-05 22.7 0.0 0.092 12.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP66657.1 - 0.00033 20.2 0.0 0.021 14.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP66657.1 - 0.0026 18.0 0.0 0.0083 16.4 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Semialdhyde_dh PF01118.19 KEP66657.1 - 0.058 13.7 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Citrate_synt PF00285.16 KEP66659.1 - 4.2e-104 348.1 0.0 6.4e-104 347.5 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase Phe_tRNA-synt_N PF02912.13 KEP66659.1 - 0.041 13.5 0.2 0.093 12.4 0.1 1.6 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DWNN PF08783.6 KEP66660.1 - 0.00026 20.8 0.0 0.00065 19.5 0.0 1.7 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_3 PF13920.1 KEP66660.1 - 0.029 14.0 9.9 0.064 12.9 6.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP66660.1 - 0.056 13.4 12.5 0.15 12.1 8.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 KEP66660.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-RING_5 PF14634.1 KEP66660.1 - 0.53 10.0 15.5 0.086 12.5 8.0 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 KEP66660.1 - 4.6 7.1 12.6 13 5.7 8.7 1.8 1 0 0 1 1 1 0 Ring finger domain Peptidase_S24 PF00717.18 KEP66661.1 - 1.3e-11 43.9 0.0 1.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KEP66661.1 - 2.3e-05 23.9 0.0 0.00013 21.4 0.0 2.0 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 IPK PF03770.11 KEP66662.1 - 1.9e-34 119.0 0.0 2.9e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase BTB PF00651.26 KEP66664.1 - 2.2e-05 24.4 1.0 3.4e-05 23.7 0.2 1.6 2 0 0 2 2 2 1 BTB/POZ domain NIL PF09383.5 KEP66664.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 NIL domain DUF3223 PF11523.3 KEP66665.1 - 2.8e-11 43.5 0.2 5.4e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) La PF05383.12 KEP66665.1 - 9.5e-09 34.9 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 La domain DnaA_N PF11638.3 KEP66665.1 - 0.078 12.5 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 DnaA N-terminal domain DUF45 PF01863.12 KEP66665.1 - 0.98 9.1 7.4 0.5 10.1 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF45 MMPL PF03176.10 KEP66665.1 - 4.2 5.9 5.3 93 1.5 0.0 2.3 3 0 0 3 3 3 0 MMPL family DUF3989 PF13150.1 KEP66667.1 - 0.052 13.0 0.1 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) EphA2_TM PF14575.1 KEP66668.1 - 0.035 14.4 0.2 0.086 13.2 0.2 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KEP66668.1 - 0.061 13.5 0.5 0.086 13.0 0.0 1.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SMC_hinge PF06470.8 KEP66669.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain ABC_tran PF00005.22 KEP66671.1 - 1.1e-36 126.1 0.0 3.3e-36 124.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 KEP66671.1 - 2.6e-15 56.5 3.4 4.1e-15 55.9 2.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KEP66671.1 - 1.8e-07 31.4 0.0 0.00051 20.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEP66671.1 - 1.1e-06 28.0 0.0 3.3e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KEP66671.1 - 0.00018 20.7 0.0 0.00035 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEP66671.1 - 0.00049 20.9 0.0 0.001 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEP66671.1 - 0.0005 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KEP66671.1 - 0.0011 18.9 0.0 0.0033 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEP66671.1 - 0.0016 18.6 0.0 0.006 16.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEP66671.1 - 0.0094 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KEP66671.1 - 0.0094 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KEP66671.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MobB PF03205.9 KEP66671.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KEP66671.1 - 0.02 14.3 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 KEP66671.1 - 0.022 14.6 0.0 0.099 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEP66671.1 - 0.029 14.8 0.0 0.062 13.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 KEP66671.1 - 0.032 14.0 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEP66671.1 - 0.06 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KEP66671.1 - 0.06 13.2 0.2 0.63 9.9 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 KEP66671.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 KEP66671.1 - 0.062 12.6 0.2 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KEP66671.1 - 0.09 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 KEP66671.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KEP66671.1 - 0.22 11.3 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Septin PF00735.13 KEP66671.1 - 0.31 10.0 0.0 0.52 9.2 0.0 1.2 1 0 0 1 1 1 0 Septin ACDC PF14733.1 KEP66672.1 - 1.2e-18 67.0 0.0 1.7e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 KEP66672.1 - 1.7e-08 34.4 0.7 3.6e-08 33.4 0.5 1.5 1 0 0 1 1 1 1 AP2 domain MSC PF09402.5 KEP66673.1 - 2.4e-09 36.3 0.1 4e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain C_GCAxxG_C_C PF09719.5 KEP66673.1 - 0.049 13.4 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) NDK PF00334.14 KEP66674.1 - 2.6e-09 36.9 0.0 2.9e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF2505 PF10698.4 KEP66674.1 - 0.0067 15.9 0.0 0.0083 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) NDK PF00334.14 KEP66675.1 - 1.1e-49 167.6 0.0 2.8e-28 98.3 0.0 2.6 2 0 0 2 2 2 2 Nucleoside diphosphate kinase ADK PF00406.17 KEP66675.1 - 3e-19 69.3 0.3 7.8e-10 38.8 0.0 3.8 4 0 0 4 4 4 2 Adenylate kinase SKI PF01202.17 KEP66675.1 - 5.8e-06 26.2 1.3 0.0036 17.1 0.0 3.6 4 0 0 4 4 4 2 Shikimate kinase AAA_18 PF13238.1 KEP66675.1 - 0.033 14.5 0.1 1.4 9.1 0.0 3.1 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 KEP66675.1 - 0.042 14.6 0.1 0.4 11.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain UBA_4 PF14555.1 KEP66675.1 - 0.042 13.3 0.3 4 7.0 0.0 2.6 2 0 0 2 2 2 0 UBA-like domain IPK PF03770.11 KEP66676.1 - 6.8e-07 29.1 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase BAAT_C PF08840.6 KEP66677.1 - 3.4 7.3 0.1 9.5 5.8 0.1 1.7 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aminotran_3 PF00202.16 KEP66680.1 - 1.5e-105 352.8 0.0 1.8e-105 352.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KEP66680.1 - 0.059 12.3 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II adh_short PF00106.20 KEP66681.1 - 1.7e-21 76.8 0.0 2.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEP66681.1 - 6e-10 39.2 0.0 8.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEP66681.1 - 6.3e-09 35.7 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 KEP66681.1 - 0.068 12.3 0.0 0.19 10.8 0.0 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TRAPP PF04051.11 KEP66683.1 - 1.3e-36 125.4 0.0 1.5e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-DHHC PF01529.15 KEP66684.1 - 2.2e-30 105.3 6.8 2.2e-30 105.3 4.7 2.0 1 1 0 1 1 1 1 DHHC palmitoyltransferase LPP PF04728.8 KEP66685.1 - 0.11 12.2 3.1 0.26 11.0 0.5 2.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Cas_APE2256 PF09651.5 KEP66685.1 - 0.12 12.0 4.1 0.15 11.7 0.5 2.6 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Reo_sigmaC PF04582.7 KEP66685.1 - 0.23 10.5 2.9 0.87 8.7 0.1 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF4497 PF14924.1 KEP66685.1 - 0.27 11.5 3.6 6.9 7.0 0.1 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF4497) APG6 PF04111.7 KEP66685.1 - 8.5 5.3 40.9 0.2 10.6 2.3 3.6 3 1 0 3 3 3 0 Autophagy protein Apg6 Vfa1 PF08432.5 KEP66686.1 - 0.63 10.0 10.2 3 7.8 0.2 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 KEP66686.1 - 8.1 4.3 9.3 0.21 9.5 2.0 1.5 2 0 0 2 2 2 0 CDC45-like protein HVSL PF09749.4 KEP66687.1 - 6.1e-29 100.7 1.6 1.9e-19 69.6 0.2 2.6 3 0 0 3 3 3 2 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 KEP66687.1 - 0.0091 15.7 3.1 0.035 13.8 1.0 2.4 3 0 0 3 3 3 1 2'-5' RNA ligase superfamily MIF4G PF02854.14 KEP66688.1 - 3.6e-33 114.7 3.0 5.8e-33 114.0 2.1 1.3 1 0 0 1 1 1 1 MIF4G domain DUF2363 PF10155.4 KEP66688.1 - 1.5 8.7 2.7 8.1 6.4 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) MA3 PF02847.12 KEP66688.1 - 7.3 6.3 10.1 4 7.1 2.7 2.5 2 1 0 2 2 2 0 MA3 domain Gp_dh_C PF02800.15 KEP66689.1 - 3.6e-68 227.9 1.6 4.6e-68 227.6 0.0 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KEP66689.1 - 4.3e-53 179.3 0.5 4.2e-52 176.1 0.0 2.4 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MaoC_dehydrat_N PF13452.1 KEP66689.1 - 0.072 12.8 1.7 0.11 12.2 0.3 1.9 1 1 1 2 2 2 0 N-terminal half of MaoC dehydratase TPR_14 PF13428.1 KEP66690.1 - 1.3e-26 90.6 11.6 0.0049 17.3 0.0 11.5 7 3 5 12 12 11 7 Tetratricopeptide repeat HAT PF02184.11 KEP66690.1 - 2.6e-21 75.0 52.4 1.5e-05 24.5 0.1 14.1 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 KEP66690.1 - 4.2e-19 68.7 6.5 0.0063 17.1 0.0 8.7 9 1 0 9 9 9 5 Tetratricopeptide repeat Suf PF05843.9 KEP66690.1 - 5.4e-13 49.3 19.7 0.0034 17.1 0.7 6.2 1 1 5 6 6 6 6 Suppressor of forked protein (Suf) TPR_19 PF14559.1 KEP66690.1 - 2.8e-10 40.3 0.0 0.39 11.1 0.0 6.8 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEP66690.1 - 5e-09 35.3 20.3 1.3 9.1 0.0 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEP66690.1 - 2.8e-07 30.3 13.3 3.2 7.7 0.0 8.4 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_15 PF13429.1 KEP66690.1 - 1.9e-06 27.1 12.5 0.0032 16.5 0.9 4.7 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEP66690.1 - 2.3e-06 26.9 9.3 16 5.6 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP66690.1 - 7.5e-05 22.9 14.1 18 6.0 0.2 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KEP66690.1 - 0.0018 18.0 2.7 0.0018 18.0 1.9 6.2 5 2 2 7 7 7 1 U3 small nucleolar RNA-associated protein 6 TPR_17 PF13431.1 KEP66690.1 - 0.01 15.9 2.9 6 7.3 0.0 6.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEP66690.1 - 0.023 14.5 4.2 0.11 12.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Actin PF00022.14 KEP66692.1 - 1.7e-24 86.0 0.0 1.6e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Actin PilM_2 PF11104.3 KEP66692.1 - 0.0042 16.0 0.0 0.0078 15.1 0.0 1.3 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; MitMem_reg PF13012.1 KEP66693.1 - 1.4e-31 108.9 0.4 2.4e-31 108.1 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KEP66693.1 - 3.8e-27 94.2 0.3 1.5e-26 92.3 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FAM104 PF15434.1 KEP66694.1 - 0.052 13.7 4.1 0.11 12.6 2.8 1.6 1 0 0 1 1 1 0 Family 104 LRR_4 PF12799.2 KEP66695.1 - 3.2e-12 45.7 3.4 2.4e-07 30.2 0.5 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP66695.1 - 2.3e-09 36.8 0.0 0.00024 20.7 0.0 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KEP66695.1 - 7.7e-05 22.2 2.9 0.93 9.7 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 KEP66695.1 - 0.00078 19.2 3.9 0.64 10.2 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 KEP66695.1 - 0.0016 18.2 5.9 7 7.3 0.0 4.7 4 1 0 4 4 4 2 Leucine rich repeat Latarcin PF10279.4 KEP66696.1 - 0.016 15.4 0.3 0.15 12.3 0.2 2.1 1 1 0 1 1 1 0 Latarcin precursor Secretin_N PF03958.12 KEP66696.1 - 0.018 15.1 0.1 0.024 14.7 0.1 1.3 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain DUF4201 PF13870.1 KEP66696.1 - 0.022 14.1 3.1 0.033 13.6 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FtsL PF04999.8 KEP66696.1 - 0.023 14.4 0.7 0.062 13.0 0.2 1.8 1 1 0 2 2 2 0 Cell division protein FtsL IFT57 PF10498.4 KEP66696.1 - 0.041 12.6 1.6 0.046 12.4 1.1 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PMI_typeI PF01238.16 KEP66696.1 - 0.11 11.4 0.9 0.13 11.1 0.6 1.0 1 0 0 1 1 1 0 Phosphomannose isomerase type I HALZ PF02183.13 KEP66696.1 - 0.72 9.6 5.0 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper TRC8_N PF13705.1 KEP66697.1 - 6.5 5.2 0.1 11 4.4 0.1 1.2 1 0 0 1 1 1 0 TRC8 N-terminal domain Lipase_3 PF01764.20 KEP66698.1 - 3.2e-18 65.7 0.0 5.6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) zf-CCCH PF00642.19 KEP66699.1 - 0.0043 16.6 0.2 0.0043 16.6 0.2 4.0 3 2 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FUSC_2 PF13515.1 KEP66701.1 - 9.9e-07 28.7 7.6 9.9e-07 28.7 5.3 2.8 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KEP66701.1 - 0.0093 14.6 4.8 0.019 13.6 3.3 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter SlyX PF04102.7 KEP66702.1 - 0.073 13.4 0.5 2.2 8.7 0.1 2.3 2 0 0 2 2 2 0 SlyX UPF0104 PF03706.8 KEP66703.1 - 0.11 11.7 0.3 0.15 11.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Antimicrobial10 PF08105.6 KEP66705.1 - 0.041 13.4 0.2 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Metchnikowin family CRAL_TRIO PF00650.15 KEP66707.1 - 2.7e-26 91.9 0.0 4.3e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 KEP66707.1 - 0.0079 16.4 0.1 0.049 13.8 0.0 2.1 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.1 KEP66707.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain adh_short PF00106.20 KEP66708.1 - 1.4e-14 54.3 0.0 2.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEP66708.1 - 0.0038 16.9 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 KR domain GFA PF04828.9 KEP66709.1 - 0.054 13.4 0.3 10 6.1 0.0 2.3 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 KEP66709.1 - 0.077 12.6 0.3 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal polyprenyl_synt PF00348.12 KEP66714.1 - 1.5e-44 151.8 0.0 1.2e-41 142.2 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase EF-hand_1 PF00036.27 KEP66716.1 - 1.2e-14 52.3 0.0 2.6e-06 26.3 0.0 2.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KEP66716.1 - 5.8e-14 51.9 0.0 1.1e-13 51.0 0.0 1.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 KEP66716.1 - 4.5e-13 48.6 0.3 2.3e-09 36.7 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP66716.1 - 3.7e-10 38.8 0.0 1.6e-06 27.4 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KEP66716.1 - 2e-09 36.3 0.0 1.8e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 KEP66716.1 - 0.00038 20.3 0.0 0.00053 19.8 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KEP66716.1 - 0.024 14.6 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Metallophos PF00149.23 KEP66718.1 - 5.6e-22 78.1 0.0 8.5e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.1 KEP66718.1 - 0.0016 18.1 0.0 0.0049 16.6 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KEP66718.1 - 0.0028 17.7 0.1 0.008 16.2 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KEP66718.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 EF hand Adap_comp_sub PF00928.16 KEP66720.1 - 2.5e-45 154.6 0.0 3.8e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family 14-3-3 PF00244.15 KEP66721.1 - 1.1e-82 276.6 3.0 1.2e-82 276.5 2.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Fusion_gly PF00523.13 KEP66721.1 - 0.08 10.9 0.1 0.14 10.2 0.0 1.3 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF866 PF05907.8 KEP66721.1 - 0.083 12.3 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) TPR_12 PF13424.1 KEP66721.1 - 0.11 12.5 5.6 0.093 12.6 1.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Biotin_lipoyl PF00364.17 KEP66722.1 - 4.7e-15 54.9 0.3 8.5e-15 54.1 0.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KEP66722.1 - 6e-06 25.8 0.0 0.0036 16.9 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 KEP66722.1 - 6.4e-05 22.4 0.0 0.0022 17.3 0.0 2.3 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KEP66722.1 - 0.00026 21.2 0.0 0.84 10.0 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.1 KEP66722.1 - 0.0027 17.4 0.1 0.0075 15.9 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.2 KEP66722.1 - 0.0059 15.8 0.0 0.014 14.5 0.0 1.7 1 0 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 KEP66722.1 - 0.079 12.6 0.1 0.29 10.8 0.1 2.0 1 0 0 1 1 1 0 Glycine cleavage H-protein SUZ PF12752.2 KEP66724.1 - 2e-07 31.4 0.6 2e-07 31.4 0.4 4.1 3 2 0 3 3 3 1 SUZ domain PAT1 PF09770.4 KEP66724.1 - 0.7 8.0 17.9 0.42 8.8 9.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FAM183 PF14886.1 KEP66725.1 - 8.5e-16 58.4 0.8 1.3e-15 57.8 0.5 1.3 1 1 0 1 1 1 1 FAM183A and FAM183B related LSM14 PF12701.2 KEP66726.1 - 4e-33 113.1 0.0 6.1e-33 112.5 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KEP66726.1 - 1.3e-10 41.7 7.3 2.9e-10 40.6 5.1 1.6 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.1 KEP66726.1 - 3.4e-06 26.8 0.0 5.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Helicase_C_3 PF13625.1 KEP66727.1 - 4.6e-22 78.1 0.0 9.4e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEP66727.1 - 5.2e-14 52.4 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEP66727.1 - 2.6e-12 46.4 0.0 6.5e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEP66727.1 - 2.3e-08 33.2 0.0 3.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_30 PF13604.1 KEP66727.1 - 0.0021 17.7 1.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Y_phosphatase3 PF13350.1 KEP66727.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Vfa1 PF08432.5 KEP66728.1 - 0.77 9.7 8.8 1 9.3 6.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 KEP66728.1 - 0.89 7.5 8.6 1.1 7.2 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 KEP66728.1 - 5 6.8 5.8 6.2 6.5 4.0 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KEP66728.1 - 5.4 6.8 11.0 7.8 6.3 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.1 KEP66729.1 - 1.1 8.4 30.7 1.4 8.1 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 KEP66729.1 - 2.3 8.0 18.2 2.8 7.7 12.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MIP-T3 PF10243.4 KEP66729.1 - 2.4 6.5 70.3 2.7 6.3 48.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 KEP66729.1 - 3.4 6.2 39.7 3.8 6.0 27.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pilt PF15453.1 KEP66729.1 - 4.9 6.7 29.2 6.3 6.3 20.2 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions PLRV_ORF5 PF01690.12 KEP66729.1 - 6 5.8 31.3 6.6 5.7 21.7 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Asp-B-Hydro_N PF05279.6 KEP66729.1 - 8.7 6.1 49.1 10 5.8 34.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SET PF00856.23 KEP66729.1 - 8.9 6.5 13.0 13 6.0 9.0 1.4 1 0 0 1 1 1 0 SET domain Reo_sigmaC PF04582.7 KEP66730.1 - 7.9 5.5 5.7 18 4.4 0.4 3.0 3 1 0 3 3 3 0 Reovirus sigma C capsid protein Carboxyl_trans PF01039.17 KEP66731.1 - 1.3e-141 472.3 0.0 1.9e-141 471.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KEP66731.1 - 0.01 15.0 0.2 0.12 11.5 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) SKI PF01202.17 KEP66731.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase Reo_sigmaC PF04582.7 KEP66732.1 - 0.61 9.2 11.7 0.13 11.4 0.7 3.6 2 2 2 5 5 5 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 KEP66732.1 - 2.3 7.4 43.4 0.016 14.5 4.7 4.3 4 1 0 4 4 4 0 Mechanosensitive ion channel porin domain NIF PF03031.13 KEP66733.1 - 2.8e-19 69.3 0.0 4.4e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KEP66733.1 - 0.0019 18.4 0.0 0.011 15.9 0.0 2.2 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase CUT PF02376.10 KEP66734.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 CUT domain SR-25 PF10500.4 KEP66735.1 - 4.6e-06 26.2 4.0 4.6e-06 26.2 2.8 5.3 3 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein Med26 PF08711.6 KEP66735.1 - 0.00082 18.8 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.20 KEP66737.1 - 1.2e-30 106.4 0.0 4.6e-29 101.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66737.1 - 7.6e-12 44.8 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP66737.1 - 0.094 11.6 0.0 0.26 10.2 0.0 1.7 1 0 0 1 1 1 0 Kinase-like SSP160 PF06933.6 KEP66737.1 - 0.53 8.1 2.8 0.86 7.5 1.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Neur_chan_memb PF02932.11 KEP66737.1 - 0.84 9.4 7.3 2.2 8.1 0.4 2.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pox_ser-thr_kin PF05445.6 KEP66737.1 - 1.7 7.3 0.0 2.8 6.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA_11 PF13086.1 KEP66738.1 - 1.5e-58 198.2 0.3 4.4e-58 196.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.1 KEP66738.1 - 3.5e-57 193.0 0.0 6e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain R3H PF01424.17 KEP66738.1 - 1.9e-15 56.2 0.3 3.9e-14 52.0 0.0 2.8 2 0 0 2 2 2 1 R3H domain AAA_19 PF13245.1 KEP66738.1 - 1.1e-12 47.5 1.6 2.1e-10 40.1 0.6 3.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KEP66738.1 - 4.1e-12 46.1 0.0 8.6e-09 35.2 0.0 3.3 3 1 0 3 3 3 2 AAA domain zf-AN1 PF01428.11 KEP66738.1 - 3.7e-07 29.8 5.9 7.3e-07 28.9 4.1 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Viral_helicase1 PF01443.13 KEP66738.1 - 1.5e-06 27.9 0.0 0.051 13.0 0.0 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KEP66738.1 - 2.7e-06 27.5 0.0 6.4e-05 23.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 KEP66738.1 - 6.3e-06 25.9 0.0 0.0085 15.7 0.0 3.3 3 0 0 3 3 3 1 Helicase AAA_25 PF13481.1 KEP66738.1 - 7.3e-05 22.2 0.1 0.00033 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 KEP66738.1 - 0.00019 21.5 0.0 0.00054 20.0 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 KEP66738.1 - 0.00028 20.4 0.0 0.02 14.3 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KEP66738.1 - 0.00037 20.5 5.3 0.0013 18.7 0.7 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 KEP66738.1 - 0.0038 16.7 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KEP66738.1 - 0.0056 16.1 0.0 0.02 14.3 0.0 1.9 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF2075 PF09848.4 KEP66738.1 - 0.01 14.8 0.1 0.086 11.7 0.0 2.4 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KEP66738.1 - 0.013 15.3 0.0 0.056 13.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 KEP66738.1 - 0.02 13.5 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ArgK PF03308.11 KEP66738.1 - 0.027 13.2 0.0 0.054 12.2 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 KEP66738.1 - 0.032 15.0 0.0 0.31 11.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 KEP66738.1 - 0.032 13.1 0.0 0.73 8.7 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase KaiC PF06745.8 KEP66738.1 - 0.16 11.0 0.0 0.53 9.3 0.0 1.8 2 0 0 2 2 2 0 KaiC DUF2614 PF11023.3 KEP66738.1 - 0.27 11.0 0.1 0.83 9.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) CRCB PF02537.10 KEP66739.1 - 2.5e-22 78.9 5.1 6e-13 48.7 0.2 4.0 3 1 1 4 4 4 3 CrcB-like protein Chromo PF00385.19 KEP66740.1 - 7.7e-14 51.1 3.5 9.4e-11 41.2 0.8 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Utp21 PF04192.7 KEP66741.1 - 5.6e-32 110.7 0.0 9.1e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KEP66741.1 - 5.2e-10 38.8 12.8 0.00055 19.7 0.0 9.0 11 0 0 11 11 11 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KEP66741.1 - 8.5e-09 35.2 0.2 0.00038 19.9 0.0 3.6 1 1 2 3 3 3 2 PQQ-like domain Lgl_C PF08596.5 KEP66741.1 - 0.066 11.6 0.1 3.2 6.1 0.0 2.6 2 1 1 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal Arf PF00025.16 KEP66742.1 - 2.3e-15 56.2 0.0 3.9e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KEP66742.1 - 3.7e-06 27.4 0.0 6.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEP66742.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KEP66742.1 - 0.0011 18.3 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KEP66742.1 - 0.0038 16.4 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 KEP66742.1 - 0.004 17.0 0.1 0.0079 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEP66742.1 - 0.0044 16.1 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KEP66742.1 - 0.011 16.5 0.1 0.047 14.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KEP66742.1 - 0.012 15.8 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KEP66742.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 KEP66742.1 - 0.015 15.3 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEP66742.1 - 0.016 14.8 0.1 0.038 13.6 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.1 KEP66742.1 - 0.018 15.3 0.2 0.06 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KEP66742.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 KEP66742.1 - 0.023 14.1 0.1 0.16 11.3 0.0 2.2 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 KEP66742.1 - 0.028 13.5 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 KEP66742.1 - 0.038 13.3 0.1 0.074 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEP66742.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KEP66742.1 - 0.044 13.5 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase G-alpha PF00503.15 KEP66742.1 - 0.047 12.3 0.0 0.092 11.4 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 KEP66742.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 KEP66742.1 - 0.08 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KEP66742.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEP66742.1 - 0.1 12.3 0.0 0.33 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KEP66742.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEP66742.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 KEP66742.1 - 0.16 10.5 0.0 5.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NAD_synthase PF02540.12 KEP66743.1 - 6.3e-27 94.0 0.1 1.1e-14 53.9 0.0 2.8 2 1 0 2 2 2 2 NAD synthase CN_hydrolase PF00795.17 KEP66743.1 - 9.9e-18 64.1 0.0 1.9e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 KEP66743.1 - 0.046 13.2 0.3 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Asparagine synthase RAP PF08373.5 KEP66744.1 - 5.4e-10 38.9 0.0 1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 KEP66744.1 - 6.7e-05 22.5 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF559) JAB PF01398.16 KEP66745.1 - 3.5e-34 116.9 0.0 6.9e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KEP66745.1 - 9.2e-20 70.8 4.0 1.6e-19 70.1 2.7 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KEP66745.1 - 1.2e-09 37.6 0.0 1.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GED PF02212.13 KEP66745.1 - 0.73 9.7 4.3 0.78 9.6 1.3 2.3 2 1 1 3 3 3 0 Dynamin GTPase effector domain DUF2870 PF11069.3 KEP66746.1 - 8.4e-36 121.9 0.1 1.4e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) MULE PF10551.4 KEP66747.1 - 0.13 12.4 0.1 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 MULE transposase domain Peptidase_M16 PF00675.15 KEP66748.1 - 7.1e-29 100.4 0.0 1.6e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEP66748.1 - 1.5e-23 83.4 0.1 9.3e-16 58.0 0.0 3.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain WD40 PF00400.27 KEP66749.1 - 1.8e-29 100.4 13.0 4.4e-08 32.7 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat zf-AN1 PF01428.11 KEP66750.1 - 4e-17 61.8 26.5 9.4e-09 35.0 5.6 3.2 2 1 1 3 3 3 2 AN1-like Zinc finger zinc_ribbon_5 PF13719.1 KEP66750.1 - 0.22 11.1 3.7 13 5.5 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Transp_Tc5_C PF04236.10 KEP66750.1 - 9.2 6.5 21.9 0.7 10.1 2.7 3.2 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain PS_Dcarbxylase PF02666.10 KEP66751.1 - 1.5e-35 122.3 0.0 2.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_C11 PF03415.9 KEP66752.1 - 1.2e-24 87.1 0.0 2.6e-23 82.6 0.0 2.1 2 0 0 2 2 2 1 Clostripain family EGF_CA PF07645.10 KEP66752.1 - 1.5e-15 56.9 49.0 2e-09 37.2 2.7 5.4 6 0 0 6 6 6 3 Calcium-binding EGF domain EGF_3 PF12947.2 KEP66752.1 - 4.4e-13 48.9 47.5 3.4e-08 33.3 3.7 5.3 5 0 0 5 5 5 3 EGF domain cEGF PF12662.2 KEP66752.1 - 1.7e-11 43.5 36.0 1.4e-06 27.7 2.8 4.7 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 KEP66752.1 - 0.0012 18.9 5.7 0.0012 18.9 3.9 5.2 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 KEP66752.1 - 0.0021 17.9 1.7 0.0021 17.9 1.2 5.4 5 1 0 5 5 5 3 EGF-like domain LRRC37AB_C PF14914.1 KEP66752.1 - 7.8 5.9 2.4 4.9 6.5 0.2 1.6 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain zf-C2HC5 PF06221.8 KEP66753.1 - 1.7e-08 34.0 12.2 4.7e-08 32.6 8.4 1.7 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ASCH PF04266.9 KEP66753.1 - 3e-06 27.5 0.2 9.9e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 ASCH domain Evr1_Alr PF04777.8 KEP66754.1 - 7.6e-07 28.9 0.5 0.076 12.9 0.0 3.5 3 0 0 3 3 3 2 Erv1 / Alr family Thioredoxin PF00085.15 KEP66754.1 - 0.0036 16.9 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 KEP66754.1 - 0.078 12.9 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 KEP66754.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain 14-3-3 PF00244.15 KEP66755.1 - 1.9e-27 95.8 3.9 8.2e-26 90.5 2.7 2.1 1 1 0 1 1 1 1 14-3-3 protein Herpes_IE1 PF07340.6 KEP66755.1 - 0.058 11.8 0.2 0.11 10.8 0.0 1.5 2 0 0 2 2 2 0 Cytomegalovirus IE1 protein Vps51 PF08700.6 KEP66755.1 - 0.095 12.5 0.2 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Vps51/Vps67 AIF-MLS PF14962.1 KEP66756.1 - 0.0037 16.9 2.1 0.0047 16.5 1.5 1.1 1 0 0 1 1 1 1 Mitochondria Localisation Sequence DUF2681 PF10883.3 KEP66756.1 - 0.0041 17.2 0.1 0.0053 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) RskA PF10099.4 KEP66756.1 - 0.007 16.1 1.3 0.0086 15.8 0.9 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SpoIIIAH PF12685.2 KEP66756.1 - 0.0081 15.6 1.0 0.011 15.2 0.7 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein HemX PF04375.9 KEP66756.1 - 0.018 13.6 2.0 0.021 13.4 1.4 1.0 1 0 0 1 1 1 0 HemX HIG_1_N PF04588.8 KEP66756.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Hypoxia induced protein conserved region DUF2561 PF10812.3 KEP66756.1 - 0.13 11.8 0.3 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Lamp PF01299.12 KEP66756.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.4 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) SecY PF00344.15 KEP66757.1 - 9.5e-96 320.7 18.2 1.2e-95 320.4 12.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KEP66757.1 - 6.7e-19 67.1 0.0 2.3e-18 65.3 0.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p DUF1765 PF08578.5 KEP66758.1 - 8.1e-15 54.9 7.7 1.6e-14 54.0 5.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Epimerase PF01370.16 KEP66759.1 - 5.5e-16 58.7 0.0 3.9e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEP66759.1 - 1.7e-05 23.8 0.0 5.2e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 KEP66759.1 - 0.0002 20.3 0.1 0.0019 17.1 0.1 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KEP66759.1 - 0.0028 17.5 0.7 0.006 16.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KEP66759.1 - 0.038 14.0 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 KEP66759.1 - 0.072 12.7 1.3 3.8 7.1 0.1 2.5 2 1 0 2 2 2 0 KR domain Longin PF13774.1 KEP66763.1 - 2.3e-26 91.1 0.1 3.4e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KEP66763.1 - 1.7e-16 59.6 0.0 2.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin AAA_12 PF13087.1 KEP66764.1 - 1.3e-40 138.9 0.0 5.5e-33 114.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KEP66764.1 - 2.1e-17 63.5 0.0 1.8e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KEP66764.1 - 7.1e-14 51.8 0.0 2.6e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEP66764.1 - 7.6e-11 41.6 1.0 3e-10 39.6 0.7 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEP66764.1 - 0.00097 19.2 0.0 0.0045 17.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KEP66764.1 - 0.0027 17.2 0.1 0.17 11.4 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KEP66764.1 - 0.0041 16.3 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein UvrD_C_2 PF13538.1 KEP66764.1 - 0.0049 16.9 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 KEP66764.1 - 0.012 14.6 0.4 0.026 13.4 0.0 1.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KEP66764.1 - 0.026 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KEP66764.1 - 0.027 14.6 0.1 0.069 13.3 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Aldo_ket_red PF00248.16 KEP66765.1 - 8.8e-50 169.0 0.0 1.5e-48 165.0 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Thioredoxin PF00085.15 KEP66766.1 - 1.1e-25 89.3 0.7 1.4e-25 88.9 0.5 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEP66766.1 - 1.5e-07 31.6 0.1 7.8e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 KEP66766.1 - 1.8e-07 30.7 0.0 2.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEP66766.1 - 5.6e-07 29.6 0.0 4.9e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like DIM1 PF02966.11 KEP66766.1 - 4e-05 23.1 0.0 4.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.5 KEP66766.1 - 0.00041 19.9 0.2 0.00072 19.1 0.1 1.3 1 1 0 1 1 1 1 Redoxin DUF953 PF06110.6 KEP66766.1 - 0.013 14.9 0.7 0.059 12.8 0.5 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TrbC_Ftype PF09673.5 KEP66766.1 - 0.016 14.7 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein AhpC-TSA PF00578.16 KEP66766.1 - 0.02 14.5 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_4 PF13462.1 KEP66766.1 - 0.029 14.3 0.3 6.6 6.7 0.1 2.3 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.1 KEP66766.1 - 0.097 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like DIM1 PF02966.11 KEP66767.1 - 5e-67 223.4 0.2 5.6e-67 223.3 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KEP66767.1 - 0.0029 17.2 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin RAP PF08373.5 KEP66769.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 RAP domain S1 PF00575.18 KEP66770.1 - 3e-09 36.8 0.0 0.00038 20.4 0.0 3.4 3 0 0 3 3 3 3 S1 RNA binding domain VirE2 PF07229.7 KEP66770.1 - 0.053 11.9 0.0 0.08 11.3 0.0 1.1 1 0 0 1 1 1 0 VirE2 PP2C PF00481.16 KEP66772.1 - 6.5e-13 48.6 0.1 6.5e-08 32.2 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C Kinesin PF00225.18 KEP66774.1 - 7.2e-35 120.2 0.0 1.1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Mannosyl_trans2 PF04188.8 KEP66775.1 - 2.9e-18 66.0 31.5 1.4e-13 50.5 0.3 5.6 7 0 0 7 7 7 4 Mannosyltransferase (PIG-V)) XH PF03469.9 KEP66777.1 - 0.062 12.9 2.6 0.14 11.7 1.6 1.8 1 1 0 1 1 1 0 XH domain Apolipoprotein PF01442.13 KEP66777.1 - 0.12 11.8 21.6 0.73 9.3 14.6 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3858 PF12970.2 KEP66778.1 - 0.013 15.3 0.1 0.019 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) UPF0121 PF03661.8 KEP66780.1 - 3.7e-07 29.6 4.3 5.1e-07 29.1 3.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) IQ PF00612.22 KEP66781.1 - 0.00056 19.3 0.5 0.003 17.0 0.3 2.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C3HC4_3 PF13920.1 KEP66783.1 - 1.6e-07 30.8 6.9 1.6e-07 30.8 4.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP66783.1 - 3.6e-07 30.0 11.7 3.6e-07 30.0 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEP66783.1 - 1.1e-06 28.4 11.9 1.1e-06 28.4 8.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KEP66783.1 - 1.2e-05 24.8 8.0 1.2e-05 24.8 5.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP66783.1 - 4.3e-05 23.2 11.9 4.3e-05 23.2 8.2 2.0 2 0 0 2 2 1 1 Ring finger domain ZZ PF00569.12 KEP66783.1 - 6e-05 22.4 7.7 6e-05 22.4 5.3 2.2 3 0 0 3 3 2 1 Zinc finger, ZZ type zf-RING_UBOX PF13445.1 KEP66783.1 - 8.3e-05 22.2 2.9 0.0001 21.9 1.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 KEP66783.1 - 0.00015 21.3 8.9 0.00015 21.3 6.2 2.5 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KEP66783.1 - 0.0059 16.1 6.3 0.0059 16.1 4.4 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KEP66783.1 - 0.0096 15.4 5.9 0.0096 15.4 4.1 2.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF4187 PF13821.1 KEP66783.1 - 0.1 12.2 5.3 0.29 10.7 3.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-H2C2_2 PF13465.1 KEP66783.1 - 3.3 8.1 5.1 1.4e+02 3.0 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain PP-binding_2 PF14573.1 KEP66784.1 - 5.5e-57 189.7 1.7 7.8e-57 189.3 1.2 1.2 1 0 0 1 1 1 1 Acyl-carrier PP-binding PF00550.20 KEP66784.1 - 0.0014 18.8 0.2 0.0036 17.5 0.1 1.7 1 1 0 1 1 1 1 Phosphopantetheine attachment site F420_ligase PF01996.11 KEP66784.1 - 0.044 12.8 0.1 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase PP2C PF00481.16 KEP66785.1 - 2.8e-43 148.1 0.0 2.1e-35 122.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Pkinase PF00069.20 KEP66786.1 - 6.7e-62 208.9 0.1 1e-60 205.0 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66786.1 - 2.7e-26 92.1 3.0 6e-22 77.9 0.7 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP66786.1 - 0.00023 20.2 0.1 0.00044 19.2 0.1 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KEP66786.1 - 0.0049 16.2 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KEP66786.1 - 0.01 14.9 0.3 0.018 14.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP66786.1 - 0.19 11.4 0.2 0.94 9.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family BTB PF00651.26 KEP66787.1 - 2.3e-08 34.0 3.6 9.7e-08 31.9 1.2 2.8 2 1 0 2 2 2 1 BTB/POZ domain Clat_adaptor_s PF01217.15 KEP66791.1 - 2e-47 160.5 0.1 1.2e-40 138.5 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Ribosomal_S13_N PF08069.7 KEP66792.1 - 7.2e-27 93.0 0.2 1.3e-26 92.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KEP66792.1 - 1.6e-22 79.0 1.1 2.4e-22 78.5 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 APC_CDC26 PF10471.4 KEP66792.1 - 0.054 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 MCM PF00493.18 KEP66793.1 - 7.2e-61 205.8 0.0 2e-42 145.2 0.9 3.5 3 1 0 3 3 3 3 MCM2/3/5 family Mg_chelatase PF01078.16 KEP66793.1 - 2.8e-07 29.9 0.1 2.3e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEP66793.1 - 7.3e-06 25.5 0.3 2.4e-05 23.8 0.2 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KEP66793.1 - 0.00018 21.2 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 KEP66793.1 - 0.019 13.6 0.5 0.042 12.5 0.4 1.5 1 0 0 1 1 1 0 G-protein alpha subunit MCM_N PF14551.1 KEP66793.1 - 0.058 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 MCM N-terminal domain AAA_29 PF13555.1 KEP66793.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain tRNA-synt_2 PF00152.15 KEP66794.1 - 8.1e-72 241.7 0.0 3.6e-61 206.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEP66794.1 - 1.2e-05 25.0 0.1 3.2e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEP66794.1 - 0.00062 19.0 0.1 0.0026 16.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KEP66794.1 - 0.012 15.1 0.2 0.9 9.0 0.0 2.9 4 0 0 4 4 4 0 tRNA synthetase class II core domain (G, H, P, S and T) UFD1 PF03152.9 KEP66796.1 - 5.8e-68 227.4 0.0 7.2e-68 227.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KEP66796.1 - 6.4e-05 22.5 0.0 0.00032 20.2 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Trm112p PF03966.11 KEP66797.1 - 1.3e-15 57.4 0.0 4.3e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Trm112p-like protein NADH-G_4Fe-4S_3 PF10588.4 KEP66797.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Aldedh PF00171.17 KEP66798.1 - 2.1e-18 65.8 1.9 1.8e-09 36.5 0.4 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Cytochrom_B562 PF07361.6 KEP66798.1 - 0.1 13.0 0.3 0.35 11.2 0.2 1.9 1 0 0 1 1 1 0 Cytochrome b562 Pro_isomerase PF00160.16 KEP66799.1 - 1.1e-49 168.6 0.1 1.2e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HECT PF00632.20 KEP66801.1 - 6.2e-55 186.5 0.0 1.1e-54 185.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.1 KEP66801.1 - 4.7e-08 33.4 0.0 6.6e-06 26.4 0.0 2.7 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily CENP-T PF15511.1 KEP66802.1 - 3.5 6.7 24.6 4.4 6.4 17.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T UBA PF00627.26 KEP66803.1 - 0.00091 18.9 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain zf-NADH-PPase PF09297.6 KEP66804.1 - 0.018 14.5 0.3 0.04 13.4 0.2 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.6 KEP66804.1 - 0.022 14.5 0.9 0.044 13.6 0.6 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like p25-alpha PF05517.7 KEP66805.1 - 9.9e-43 146.0 1.6 1.3e-42 145.7 1.1 1.0 1 0 0 1 1 1 1 p25-alpha DEAD PF00270.24 KEP66806.1 - 8.8e-31 106.6 0.0 1.5e-23 83.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP66806.1 - 2.7e-19 68.8 0.1 7.3e-19 67.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Transglut_core3 PF13471.1 KEP66806.1 - 0.017 14.8 0.1 0.11 12.2 0.1 2.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily AAA_22 PF13401.1 KEP66806.1 - 0.72 10.0 0.0 0.72 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain RRM_1 PF00076.17 KEP66808.1 - 1.8e-18 65.9 0.0 3e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66808.1 - 3e-16 59.1 0.0 5.3e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66808.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Caprin-1_C PF12287.3 KEP66808.1 - 0.017 14.5 8.6 0.021 14.2 5.9 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DeoC PF01791.4 KEP66809.1 - 7.2e-31 107.2 1.0 8.9e-31 106.9 0.7 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase BTV_NS2 PF04514.7 KEP66811.1 - 1.9 7.2 3.4 3.4 6.4 2.4 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dynamin_N PF00350.18 KEP66812.1 - 1.2e-14 54.4 0.0 3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KEP66812.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KEP66812.1 - 0.047 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF3263 PF11662.3 KEP66813.1 - 0.15 11.5 0.3 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) DUF4633 PF15464.1 KEP66814.1 - 2.6 7.9 8.3 0.85 9.4 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) Wbp11 PF09429.5 KEP66815.1 - 1.1e-20 73.4 12.1 1.1e-20 73.4 8.4 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 FAM110_C PF14160.1 KEP66815.1 - 2.7 8.9 8.9 0.52 11.2 0.2 2.7 2 0 0 2 2 2 0 Centrosome-associated C terminus Nipped-B_C PF12830.2 KEP66816.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Cwf_Cwc_15 PF04889.7 KEP66817.1 - 1.2e-57 195.4 25.4 8.5e-41 140.2 11.2 2.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein DUF2890 PF11081.3 KEP66817.1 - 0.033 14.2 16.3 0.03 14.3 10.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Abhydrolase_1 PF00561.15 KEP66817.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Spt5_N PF11942.3 KEP66817.1 - 0.27 11.8 15.0 0.093 13.3 7.5 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PA26 PF04636.8 KEP66817.1 - 0.38 9.3 4.5 0.42 9.2 3.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ebola_NP PF05505.7 KEP66817.1 - 2.1 6.3 11.1 2.6 5.9 7.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 KEP66817.1 - 6.7 4.6 11.8 7.4 4.4 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein HHH_5 PF14520.1 KEP66818.1 - 0.027 14.6 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 KEP66818.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Asn_synthase PF00733.16 KEP66819.1 - 2e-23 83.1 0.0 8.3e-12 45.1 0.0 2.4 2 0 0 2 2 2 2 Asparagine synthase Nab6_mRNP_bdg PF10567.4 KEP66819.1 - 1 8.3 0.5 3.1 6.7 0.0 1.9 2 0 0 2 2 2 0 RNA-recognition motif PWI PF01480.12 KEP66820.1 - 9.4e-15 54.4 0.4 3e-14 52.8 0.1 1.9 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 KEP66820.1 - 1.1e-07 31.3 0.0 2.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66820.1 - 5.1e-05 23.1 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 KEP66820.1 - 8.3 6.4 13.8 0.037 14.0 1.3 2.8 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RNA_pol_Rpb6 PF01192.17 KEP66821.1 - 8.1e-20 70.3 0.2 1.4e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF1168 PF06658.7 KEP66822.1 - 1.1e-24 86.6 24.6 1.1e-24 86.6 17.1 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) DUF2453 PF10507.4 KEP66823.1 - 8.9e-32 109.1 3.5 5.7e-31 106.6 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2453) GAF_3 PF13492.1 KEP66823.1 - 2.4e-11 43.8 0.0 1.8e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 KEP66823.1 - 1.1e-10 41.8 0.0 2.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 KEP66823.1 - 6.1e-07 30.0 0.0 3.1e-06 27.7 0.0 2.2 3 0 0 3 3 3 1 GAF domain VRR_NUC PF08774.6 KEP66824.1 - 0.039 13.9 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 VRR-NUC domain LSM PF01423.17 KEP66827.1 - 1.5e-18 66.0 0.5 2.1e-18 65.6 0.3 1.2 1 0 0 1 1 1 1 LSM domain PARP PF00644.15 KEP66828.1 - 6.3e-57 192.3 0.0 1.5e-56 191.1 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KEP66828.1 - 1.7e-30 105.4 0.5 3.6e-30 104.3 0.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KEP66828.1 - 4.7e-10 39.2 0.6 1.8e-09 37.3 0.4 2.1 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.7 KEP66828.1 - 1.4e-07 30.7 0.1 4.7e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 PADR1 (NUC008) domain zf-PARP PF00645.13 KEP66828.1 - 1.6e-07 31.4 0.0 3.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region BRCT PF00533.21 KEP66828.1 - 2.8e-07 30.6 0.0 1.6e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEP66828.1 - 0.0096 15.7 0.0 0.065 13.1 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain Glyco_hydro_17 PF00332.13 KEP66829.1 - 1.6e-37 129.2 0.0 2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Guanylate_cyc PF00211.15 KEP66830.1 - 2.2e-20 72.8 0.0 8e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain RRM_1 PF00076.17 KEP66832.1 - 1.3e-06 27.9 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66832.1 - 3.1e-05 23.8 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66832.1 - 0.0097 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 KEP66834.1 - 2e-12 47.4 0.0 4.9e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEP66834.1 - 1.2e-05 25.4 0.0 4.9e-05 23.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KEP66834.1 - 2.1e-05 24.5 6.0 0.00013 21.9 0.0 3.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KEP66834.1 - 0.00027 20.0 0.0 0.00054 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 KEP66834.1 - 0.00046 18.9 0.0 0.15 10.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KEP66834.1 - 0.00047 20.9 0.1 0.0025 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEP66834.1 - 0.0017 18.0 0.0 0.0049 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KEP66834.1 - 0.0027 16.8 0.0 0.007 15.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 KEP66834.1 - 0.004 16.8 4.4 0.0041 16.8 0.0 3.1 3 1 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 KEP66834.1 - 0.0073 15.7 0.2 0.26 10.6 0.2 2.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KEP66834.1 - 0.013 15.1 0.1 0.3 10.7 0.1 2.5 1 1 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KEP66834.1 - 0.041 13.5 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 KEP66834.1 - 0.047 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 KEP66834.1 - 0.16 11.8 0.0 0.56 10.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 KEP66834.1 - 0.34 10.4 0.0 0.57 9.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_18 PF13238.1 KEP66834.1 - 0.75 10.1 4.3 0.79 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Acyltransferase PF01553.16 KEP66835.1 - 9.2e-11 41.3 0.0 1.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Kinase-like PF14531.1 KEP66836.1 - 9.8e-24 83.8 0.0 7.2e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 KEP66836.1 - 1.3e-16 60.5 0.0 2.5e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KEP66836.1 - 0.0025 16.9 0.0 0.0073 15.3 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEP66836.1 - 0.045 13.1 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Ribosomal_L44 PF00935.14 KEP66837.1 - 0.087 12.8 0.2 0.11 12.5 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L44 Tho2 PF11262.3 KEP66838.1 - 1.7e-59 201.2 0.0 1.4e-45 155.6 0.0 2.3 2 0 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.4 KEP66838.1 - 8.4 5.2 8.8 18 4.1 6.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med5 PF08689.5 KEP66838.1 - 9.4 3.7 0.0 17 2.8 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit Med5 DUF972 PF06156.8 KEP66839.1 - 0.0037 17.5 10.7 0.045 14.0 1.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF972) Bap31 PF05529.7 KEP66839.1 - 0.15 11.5 13.7 0.014 14.8 1.7 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF1664 PF07889.7 KEP66839.1 - 0.27 11.0 3.2 3.6 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.1 KEP66839.1 - 0.28 11.1 5.4 0.99 9.3 3.8 2.0 1 0 0 1 1 1 0 FlxA-like protein Myosin_tail_1 PF01576.14 KEP66839.1 - 0.45 8.1 28.2 1.7 6.2 19.5 1.8 1 1 0 1 1 1 0 Myosin tail Filament PF00038.16 KEP66839.1 - 0.8 9.1 20.2 2.2 7.6 13.6 1.7 1 1 0 1 1 1 0 Intermediate filament protein ADIP PF11559.3 KEP66839.1 - 1.7 8.5 22.5 0.028 14.3 3.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2265 PF10023.4 KEP66839.1 - 2.1 7.4 9.0 3.2 6.7 6.2 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) AAA_13 PF13166.1 KEP66839.1 - 2.9 6.2 9.4 7.1 4.9 6.2 1.6 1 1 0 1 1 1 0 AAA domain CENP-Q PF13094.1 KEP66839.1 - 3.7 7.5 29.2 0.25 11.3 7.3 2.8 2 1 1 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Nup88 PF10168.4 KEP66839.1 - 6.7 4.4 7.3 10 3.7 5.0 1.2 1 0 0 1 1 1 0 Nuclear pore component CALCOCO1 PF07888.6 KEP66839.1 - 9 4.4 18.8 15 3.7 13.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Siva PF05458.7 KEP66840.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF1414 PF07208.6 KEP66840.1 - 0.12 12.1 0.2 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1414) DUF4106 PF13388.1 KEP66840.1 - 1.1 8.1 3.0 1.6 7.6 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF1253 PF06862.7 KEP66841.1 - 7.9e-120 400.2 0.2 2.4e-76 256.9 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) DUF1467 PF07330.7 KEP66844.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) EF-hand_7 PF13499.1 KEP66845.1 - 0.0022 18.0 0.1 7.3 6.8 0.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair AP2 PF00847.15 KEP66849.1 - 4.5e-09 36.3 0.4 9.2e-09 35.3 0.3 1.6 1 0 0 1 1 1 1 AP2 domain SAG PF04092.8 KEP66851.1 - 5e-05 23.6 0.1 6.5e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 SRS domain SAG PF04092.8 KEP66852.1 - 3.4e-13 50.0 0.9 4.4e-13 49.7 0.6 1.2 1 0 0 1 1 1 1 SRS domain Sec1 PF00995.18 KEP66853.1 - 1e-143 479.9 0.0 1.2e-143 479.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PYC_OADA PF02436.13 KEP66853.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain SNF2_N PF00176.18 KEP66853.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain OTU PF02338.14 KEP66854.1 - 1.3e-09 38.7 0.0 2.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease COMP PF11598.3 KEP66855.1 - 0.0083 16.1 0.3 0.0083 16.1 0.2 3.1 4 0 0 4 4 4 1 Cartilage oligomeric matrix protein FlaC_arch PF05377.6 KEP66855.1 - 0.32 10.9 2.5 36 4.3 0.1 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Vps51 PF08700.6 KEP66855.1 - 6.8 6.6 13.2 3.9 7.3 0.4 4.1 4 0 0 4 4 4 0 Vps51/Vps67 FAD-SLDH PF12318.3 KEP66856.1 - 0.57 9.8 2.5 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase NUC153 PF08159.7 KEP66857.1 - 2.7e-13 49.2 10.3 2.5e-11 42.9 1.8 2.9 2 0 0 2 2 2 2 NUC153 domain TFIIA PF03153.8 KEP66857.1 - 0.0042 17.0 19.1 0.0042 17.0 13.3 4.2 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit RRM_5 PF13893.1 KEP66857.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos PF03372.18 KEP66859.1 - 7.5e-15 55.5 0.3 4.2e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family IncA PF04156.9 KEP66861.1 - 2.1 7.8 4.3 0.71 9.4 0.1 2.4 2 0 0 2 2 2 0 IncA protein DUF996 PF06195.8 KEP66862.1 - 0.014 15.4 0.1 0.014 15.4 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF996) SKG6 PF08693.5 KEP66862.1 - 0.075 12.3 0.0 0.25 10.6 0.0 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1118 PF06549.7 KEP66862.1 - 0.29 11.2 2.1 0.23 11.6 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1118) ARGLU PF15346.1 KEP66863.1 - 8.4e-27 93.7 37.2 9.4e-27 93.6 25.8 1.0 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 CAF-1_p150 PF11600.3 KEP66863.1 - 1.9 7.7 36.9 2.4 7.4 25.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF874 PF05917.6 KEP66863.1 - 5 5.8 14.7 6.2 5.5 10.2 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF4407 PF14362.1 KEP66863.1 - 7.5 5.4 13.9 11 4.8 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bin3 PF06859.7 KEP66864.1 - 3e-25 88.3 0.0 5e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 KEP66864.1 - 2.3e-11 44.2 0.1 7e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 KEP66864.1 - 5.3e-11 42.4 0.0 0.00026 20.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 KEP66864.1 - 5.5e-10 39.0 0.0 6.5e-06 25.8 0.1 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KEP66864.1 - 5.4e-06 26.8 0.1 0.032 14.7 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KEP66864.1 - 7.3e-06 26.3 0.1 0.14 12.6 0.1 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KEP66864.1 - 6.3e-05 22.9 0.0 0.00038 20.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEP66864.1 - 0.00015 21.0 0.2 0.00024 20.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KEP66864.1 - 0.00034 20.9 0.2 0.035 14.4 0.1 2.6 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 KEP66864.1 - 0.00061 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 KEP66864.1 - 0.0016 17.8 0.1 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain EutQ PF06249.7 KEP66864.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Glyco_hydro_77 PF02446.12 KEP66866.1 - 3.9e-120 401.7 0.5 5.3e-120 401.3 0.3 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase FAST_1 PF06743.10 KEP66868.1 - 0.012 15.3 0.0 10 5.9 0.0 4.4 3 1 0 4 4 4 0 FAST kinase-like protein, subdomain 1 AKAP7_NLS PF10469.4 KEP66869.1 - 1.7e-57 194.4 0.0 2.9e-57 193.7 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.24 KEP66869.1 - 1.4e-10 40.6 0.4 3.7e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KEP66869.1 - 1.9e-08 33.7 0.0 4.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 KH domain MAS20 PF02064.10 KEP66871.1 - 0.2 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor UPF0113 PF03657.8 KEP66872.1 - 1.2e-10 41.3 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) LRR_4 PF12799.2 KEP66873.1 - 6.6e-19 67.1 17.4 4e-05 23.1 0.0 5.7 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP66873.1 - 2.9e-10 39.7 14.7 5.4e-07 29.2 1.5 4.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.1 KEP66873.1 - 3.5e-06 26.6 2.7 0.019 14.5 0.2 2.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 KEP66873.1 - 6e-06 25.5 29.4 0.67 10.2 0.5 9.5 8 2 2 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.1 KEP66873.1 - 0.0021 17.9 13.7 38 4.7 0.9 7.8 7 2 1 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 KEP66873.1 - 0.0072 16.3 24.0 14 6.4 0.0 9.0 10 0 0 10 10 10 1 Leucine rich repeat DRY_EERY PF09750.4 KEP66874.1 - 1.7e-11 44.2 0.2 1.7e-11 44.2 0.2 2.5 2 0 0 2 2 2 1 Alternative splicing regulator Surp PF01805.15 KEP66874.1 - 3.1e-06 26.7 0.1 0.008 15.8 0.0 2.6 2 0 0 2 2 2 2 Surp module SHS2_Rpb7-N PF03876.12 KEP66875.1 - 7e-14 51.7 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KEP66875.1 - 6.7e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF4471 PF14740.1 KEP66877.1 - 4.6e-45 154.0 5.0 6.3e-45 153.6 3.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4471) DUF4470 PF14737.1 KEP66877.1 - 1.9e-19 69.2 0.5 9.2e-19 67.0 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4470) SAPS PF04499.10 KEP66878.1 - 0.64 8.5 5.4 0.83 8.2 3.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YL1 PF05764.8 KEP66878.1 - 2.1 7.9 17.8 3 7.3 12.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Mur_ligase_M PF08245.7 KEP66880.1 - 8.9e-11 42.1 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Use1 PF09753.4 KEP66880.1 - 0.0079 15.6 2.0 0.013 14.9 1.4 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Ub-Mut7C PF14451.1 KEP66880.1 - 0.048 13.1 0.1 0.16 11.4 0.0 1.9 1 0 0 1 1 1 0 Mut7-C ubiquitin Mur_ligase_C PF02875.16 KEP66880.1 - 0.057 13.4 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain SRP54 PF00448.17 KEP66880.1 - 0.074 12.4 0.2 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.18 KEP66880.1 - 0.078 12.3 0.1 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PUB PF09409.5 KEP66883.1 - 2.7e-15 55.9 0.0 4.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 PUB domain Utp11 PF03998.8 KEP66884.1 - 1.2e-23 84.2 25.9 8.3e-20 71.6 18.0 3.0 1 1 0 1 1 1 1 Utp11 protein Rod_cone_degen PF15201.1 KEP66884.1 - 4.3 7.2 5.3 1.6 8.6 1.1 2.2 2 0 0 2 2 2 0 Progressive rod-cone degeneration Neisseria_TspB PF05616.8 KEP66886.1 - 3.2 6.0 12.9 3.9 5.7 9.0 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein FAM75 PF14650.1 KEP66886.1 - 4.5 6.5 5.6 4.4 6.5 3.9 1.0 1 0 0 1 1 1 0 FAM75 family COPR5 PF15340.1 KEP66886.1 - 6 7.2 8.1 7.1 6.9 5.6 1.2 1 0 0 1 1 1 0 Cooperator of PRMT5 family TFIIF_alpha PF05793.7 KEP66886.1 - 8.2 4.6 21.2 8.7 4.5 14.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Porphobil_deam PF01379.15 KEP66887.1 - 9.7e-53 178.2 0.0 2.4e-27 95.2 0.0 4.2 4 0 0 4 4 4 4 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KEP66887.1 - 1.1e-13 51.0 0.9 9.6e-13 48.0 0.6 2.2 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF2628 PF10947.3 KEP66887.1 - 0.033 13.9 0.3 0.065 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) TPR_12 PF13424.1 KEP66888.1 - 0.003 17.4 1.6 3.8 7.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEP66888.1 - 0.019 14.8 3.9 1 9.4 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP66888.1 - 2.3 8.8 4.1 26 5.5 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat NPL4 PF05021.10 KEP66889.1 - 1.7e-67 227.7 0.0 2.3e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.3 KEP66889.1 - 3e-10 40.2 0.0 2e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.10 KEP66889.1 - 1.2e-05 25.0 0.1 3e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region U79_P34 PF03064.11 KEP66890.1 - 0.22 11.0 6.8 0.25 10.8 4.7 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Abhydrolase_5 PF12695.2 KEP66891.1 - 3.3e-18 65.8 0.0 1.8e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP66891.1 - 1.1e-12 48.3 1.0 1.1e-12 48.3 0.7 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP66891.1 - 0.00017 21.2 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEP66891.1 - 0.00019 21.2 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 KEP66891.1 - 0.0013 18.1 0.0 0.0047 16.3 0.0 2.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) P5CR_dimer PF14748.1 KEP66895.1 - 4.1e-30 103.9 0.6 7.8e-30 103.0 0.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KEP66895.1 - 2.2e-10 40.8 0.1 4.8e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KEP66895.1 - 0.00015 21.6 0.1 0.0003 20.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KEP66895.1 - 0.022 14.4 0.5 0.2 11.3 0.3 2.2 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KEP66895.1 - 0.097 12.7 0.2 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Caps_synth_CapC PF14102.1 KEP66895.1 - 0.1 12.6 0.0 0.37 10.9 0.0 1.8 1 1 0 1 1 1 0 Capsule biosynthesis CapC tRNA-synt_2b PF00587.20 KEP66896.1 - 6.6e-24 84.4 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_S66 PF02016.10 KEP66896.1 - 0.19 10.6 0.3 26 3.6 0.0 2.8 3 0 0 3 3 3 0 LD-carboxypeptidase EF-hand_6 PF13405.1 KEP66898.1 - 9.1e-07 28.2 0.1 0.012 15.4 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KEP66898.1 - 1.6e-06 28.1 0.1 0.0045 17.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP66898.1 - 0.00072 18.6 0.1 0.15 11.4 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KEP66898.1 - 0.0029 17.4 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain Thioredoxin_6 PF13848.1 KEP66899.1 - 5.6e-27 94.7 0.0 2.7e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.15 KEP66899.1 - 2.9e-19 68.6 0.0 6.6e-10 38.6 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_7 PF13899.1 KEP66899.1 - 0.0002 21.2 0.1 0.31 11.1 0.0 3.4 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KEP66899.1 - 0.00023 21.2 0.0 0.46 10.6 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KEP66899.1 - 0.00063 19.9 0.0 0.075 13.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KEP66899.1 - 0.2 11.3 0.1 0.81 9.3 0.0 2.0 3 0 0 3 3 3 0 AhpC/TSA family 7tm_6 PF02949.15 KEP66900.1 - 0.58 8.9 0.0 1.2 7.8 0.0 1.5 1 0 0 1 1 1 0 7tm Odorant receptor Filamin PF00630.14 KEP66901.1 - 2.8e-16 59.9 0.1 9.9e-11 42.1 0.0 3.6 3 0 0 3 3 3 2 Filamin/ABP280 repeat EB1 PF03271.12 KEP66902.1 - 0.0037 17.2 1.2 0.0079 16.2 0.8 1.7 1 1 0 1 1 1 1 EB1-like C-terminal motif DUF676 PF05057.9 KEP66903.1 - 2.4e-29 102.1 0.0 2.4e-25 89.1 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEP66903.1 - 0.00021 21.2 1.2 0.00074 19.4 0.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP66903.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LRR_9 PF14580.1 KEP66904.1 - 2.6e-11 43.4 0.0 3.9e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KEP66904.1 - 3.9e-10 39.1 2.8 2.3e-05 23.9 0.0 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP66904.1 - 2.8e-05 23.7 1.3 0.0025 17.5 0.3 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 KEP66904.1 - 0.0028 17.5 0.3 40 4.7 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 KEP66904.1 - 0.18 12.0 1.3 6.2 7.4 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat Lip_prot_lig_C PF10437.4 KEP66905.1 - 4.3e-19 67.9 0.0 1.3e-18 66.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.14 KEP66905.1 - 1.7e-17 63.5 0.0 3.2e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RAP PF08373.5 KEP66906.1 - 2e-05 24.2 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RAP domain tRNA_U5-meth_tr PF05958.6 KEP66908.1 - 1e-19 70.5 0.0 1.8e-19 69.6 0.0 1.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 KEP66908.1 - 5e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP66908.1 - 6.5e-05 23.4 0.0 0.00017 22.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP66908.1 - 6.7e-05 22.5 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEP66908.1 - 0.012 15.2 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KEP66908.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KEP66908.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KEP66908.1 - 0.094 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Endonuclease_7 PF02945.10 KEP66908.1 - 0.1 12.3 0.6 0.33 10.6 0.4 1.8 1 0 0 1 1 1 0 Recombination endonuclease VII Peptidase_M14 PF00246.19 KEP66909.1 - 9.5e-33 113.9 0.0 1.5e-27 96.9 0.0 2.7 1 1 1 2 2 2 2 Zinc carboxypeptidase zf-B_box PF00643.19 KEP66910.1 - 7.1e-10 38.6 12.4 3.1e-05 23.7 2.0 2.5 2 0 0 2 2 2 2 B-box zinc finger TFIIA PF03153.8 KEP66910.1 - 0.00011 22.2 34.6 0.00083 19.3 0.5 2.7 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit adh_short PF00106.20 KEP66911.1 - 4.1e-22 78.8 0.1 5.6e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEP66911.1 - 5.2e-08 32.9 0.0 7.1e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEP66911.1 - 2.4e-06 27.3 0.1 3.7e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEP66911.1 - 4.9e-05 23.4 0.1 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 KEP66911.1 - 0.00072 18.7 0.0 0.0042 16.2 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_tran_WecB PF03808.8 KEP66911.1 - 0.0053 16.1 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family F420_oxidored PF03807.12 KEP66911.1 - 0.012 16.0 0.1 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KEP66911.1 - 0.11 11.9 0.2 0.41 10.0 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEP66911.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Thioesterase PF00975.15 KEP66912.1 - 5.4e-16 59.5 0.0 1.9e-15 57.7 0.0 1.8 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 KEP66912.1 - 1.6e-10 41.2 0.0 2.6e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP66912.1 - 1.1e-07 31.7 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEP66912.1 - 0.015 14.8 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 KEP66912.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DnaJ PF00226.26 KEP66913.1 - 4.3e-14 51.9 0.2 2.3e-13 49.6 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain Nop14 PF04147.7 KEP66914.1 - 0.78 7.5 19.0 1.4 6.7 13.2 1.3 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 KEP66914.1 - 1.7 7.7 10.8 3.1 6.8 7.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 KEP66914.1 - 2.6 5.9 23.7 1.6 6.6 0.0 3.1 2 1 0 2 2 2 0 CDC45-like protein ketoacyl-synt PF00109.21 KEP66915.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Amidase PF01425.16 KEP66917.1 - 4.6e-07 29.0 0.0 0.0043 15.9 0.0 3.4 4 0 0 4 4 4 2 Amidase DUF3273 PF11677.3 KEP66919.1 - 4.1e-80 268.8 7.7 4.9e-80 268.5 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) SAG PF04092.8 KEP66921.1 - 2.1e-29 102.3 0.0 1.1e-05 25.8 0.0 5.2 5 0 0 5 5 5 5 SRS domain TFIIS_C PF01096.13 KEP66921.1 - 0.064 12.9 0.1 5.1 6.8 0.0 3.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) DUF2019 PF09450.5 KEP66922.1 - 0.55 10.1 3.0 1.3 8.9 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Atg14 PF10186.4 KEP66922.1 - 1.3 7.8 18.4 18 4.1 12.8 2.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Erp_C PF06780.6 KEP66923.1 - 0.15 11.8 5.5 0.33 10.7 3.8 1.6 1 0 0 1 1 1 0 Erp protein C-terminus Gar1 PF04410.9 KEP66925.1 - 2.7e-41 140.6 1.7 2.7e-41 140.6 1.2 2.2 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Kelch_1 PF01344.20 KEP66926.1 - 4.5e-36 122.1 0.0 2e-12 46.4 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 KEP66926.1 - 2e-21 75.1 0.0 1e-05 25.4 0.0 6.0 3 2 3 6 6 6 4 Kelch motif Kelch_4 PF13418.1 KEP66926.1 - 7.1e-20 70.5 0.2 3.1e-05 23.6 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP66926.1 - 1.1e-19 70.0 0.1 1.2e-06 28.5 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 KEP66926.1 - 4.3e-11 42.1 0.3 0.00027 20.5 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 KEP66926.1 - 4.1e-10 39.3 1.9 0.0066 16.3 0.0 4.6 4 0 0 4 4 4 2 Kelch motif WD40 PF00400.27 KEP66927.1 - 5.1e-06 26.1 21.0 0.025 14.4 0.2 7.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Ycf1 PF05758.7 KEP66927.1 - 0.095 10.4 1.3 0.19 9.4 0.9 1.4 1 0 0 1 1 1 0 Ycf1 Steroid_dh PF02544.11 KEP66929.1 - 2.2e-09 37.2 0.0 7.6e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase Pkinase PF00069.20 KEP66931.1 - 3.9e-55 186.7 0.5 3.1e-36 124.8 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66931.1 - 1.7e-24 86.2 0.1 4.5e-18 65.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEP66931.1 - 2.9e-07 30.4 0.1 0.00052 19.8 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP66931.1 - 0.00013 21.0 0.3 0.0077 15.2 0.0 2.8 3 0 0 3 3 3 1 Kinase-like YukC PF10140.4 KEP66931.1 - 0.049 12.2 1.2 0.088 11.3 0.0 1.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.6 KEP66931.1 - 0.057 12.2 0.2 0.093 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KEP66931.1 - 0.22 10.3 0.1 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cons_hypoth95 PF03602.10 KEP66932.1 - 5.4e-29 100.8 0.0 1.9e-22 79.5 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KEP66932.1 - 0.00081 19.4 0.0 0.0028 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP66932.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KEP66932.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Proteasome PF00227.21 KEP66933.1 - 9.3e-21 73.9 0.1 2.2e-20 72.7 0.1 1.5 1 1 0 1 1 1 1 Proteasome subunit Dpy-30 PF05186.8 KEP66935.1 - 2.9e-13 49.0 0.0 7.4e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 Dpy-30 motif BDHCT PF08072.6 KEP66935.1 - 0.8 9.8 3.4 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 BDHCT (NUC031) domain Wyosine_form PF08608.7 KEP66937.1 - 1.5e-24 85.8 0.1 4.5e-24 84.3 0.0 1.9 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.16 KEP66937.1 - 2.8e-23 82.8 0.0 5.1e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 KEP66937.1 - 1.5e-06 28.2 0.0 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin PP2C PF00481.16 KEP66938.1 - 1.4e-42 145.9 0.2 9.8e-27 93.9 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KEP66938.1 - 2.9e-07 30.0 0.0 2.4e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEP66938.1 - 1.9e-06 27.7 0.0 0.0001 22.0 0.0 2.3 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) TPR_12 PF13424.1 KEP66939.1 - 1.8e-06 27.8 2.3 0.02 14.8 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEP66939.1 - 0.0072 15.9 0.1 0.066 12.8 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEP66939.1 - 0.016 15.0 0.3 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP66939.1 - 0.019 14.7 0.5 1.8 8.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEP66939.1 - 0.12 12.0 0.0 8.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Transket_pyr PF02779.19 KEP66940.1 - 1.7e-46 157.9 0.0 2.5e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEP66940.1 - 5.7e-32 110.2 0.2 1.2e-31 109.2 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain zf-DHHC PF01529.15 KEP66941.1 - 4.9e-29 100.9 0.2 7.8e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.2 KEP66941.1 - 1.7e-23 82.7 1.6 1.7e-11 44.3 0.7 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEP66941.1 - 4.1e-18 64.2 4.7 4.4e-08 32.5 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KEP66941.1 - 8.6e-17 61.1 3.6 1e-07 32.2 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEP66941.1 - 1.1e-13 50.9 10.3 3.1e-05 24.0 0.1 5.8 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP66941.1 - 2.5e-11 42.6 5.8 0.00077 19.4 0.1 5.0 4 0 0 4 4 4 3 Ankyrin repeat Telomere_Sde2_2 PF13297.1 KEP66942.1 - 1e-20 72.7 0.0 2.4e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal Telomere_Sde2 PF13019.1 KEP66942.1 - 3.5e-14 52.8 0.2 3.5e-14 52.8 0.2 2.9 2 1 2 4 4 4 1 Telomere stability and silencing Torsin PF06309.6 KEP66942.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Torsin FAM176 PF14851.1 KEP66942.1 - 4.3 7.0 12.0 6.7 6.3 1.7 2.6 2 0 0 2 2 2 0 FAM176 family WD40 PF00400.27 KEP66943.1 - 2.2e-29 100.2 7.7 4.3e-08 32.7 0.3 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF3312 PF11768.3 KEP66943.1 - 0.00054 18.3 0.0 0.0011 17.2 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) DUF1126 PF06565.7 KEP66944.1 - 3.4e-29 100.0 0.6 1.3e-14 53.3 0.0 3.2 3 0 0 3 3 3 2 Repeat of unknown function (DUF1126) 2TM PF13239.1 KEP66945.1 - 3 7.9 4.1 44 4.2 0.0 3.4 3 0 0 3 3 3 0 2TM domain CK_II_beta PF01214.13 KEP66949.1 - 6.3e-66 221.3 0.0 9e-66 220.8 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit NAD_binding_2 PF03446.10 KEP66950.1 - 4.3e-22 78.6 0.0 2.6e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KEP66950.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KEP66950.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KEP66950.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LCAT PF02450.10 KEP66953.1 - 5.9e-38 130.8 0.0 6.4e-34 117.5 0.1 2.2 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 KEP66953.1 - 0.045 13.0 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) MACPF PF01823.14 KEP66954.1 - 2.7e-45 154.6 0.0 4.8e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 MAC/Perforin domain RRM_1 PF00076.17 KEP66955.1 - 1e-17 63.5 0.0 1.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66955.1 - 5.1e-17 61.6 0.0 8.6e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66955.1 - 1.5e-10 40.7 0.0 2.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEP66955.1 - 0.0017 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.6 KEP66955.1 - 0.0048 16.3 0.0 0.0094 15.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain Neur_chan_memb PF02932.11 KEP66956.1 - 0.059 13.2 0.3 0.092 12.6 0.2 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TPR_16 PF13432.1 KEP66956.1 - 3.2 8.5 8.7 0.52 11.0 0.4 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 KEP66957.1 - 5.7e-40 137.0 0.0 1.9e-24 86.2 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66957.1 - 7.5e-39 133.3 0.0 2e-27 95.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase NAD_binding_8 PF13450.1 KEP66958.1 - 0.0012 18.8 0.2 0.64 10.0 0.1 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEP66958.1 - 0.0029 16.7 0.4 0.0078 15.3 0.3 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Sugar_tr PF00083.19 KEP66959.1 - 8e-85 285.0 23.2 1.3e-84 284.4 16.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEP66959.1 - 3e-27 95.2 51.0 1.8e-25 89.4 16.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEP66959.1 - 1.3 7.1 13.3 0.014 13.6 1.1 2.8 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) Asp PF00026.18 KEP66960.1 - 1.3e-51 175.7 0.0 2.3e-51 174.9 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEP66960.1 - 0.0031 17.5 0.0 0.0072 16.2 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal DUF1510 PF07423.6 KEP66961.1 - 8.2 5.7 16.0 11 5.2 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SNase PF00565.12 KEP66962.1 - 0.2 11.8 1.0 0.82 9.9 0.3 2.3 2 1 0 2 2 2 0 Staphylococcal nuclease homologue Pkinase PF00069.20 KEP66963.1 - 1.3e-58 198.2 0.0 3.5e-37 127.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP66963.1 - 4.1e-28 98.1 0.0 8.3e-19 67.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEP66963.1 - 0.00037 19.5 0.2 0.33 9.8 0.1 2.3 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 KEP66963.1 - 0.13 11.5 0.0 6 6.1 0.0 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KEP66963.1 - 0.32 9.8 0.0 0.49 9.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SMK-1 PF04802.10 KEP66964.1 - 1.3e-21 76.9 1.8 3.3e-21 75.6 1.3 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 SAG PF04092.8 KEP66965.1 - 1.2e-38 132.2 24.1 8.4e-24 84.3 2.3 2.6 2 1 1 3 3 3 2 SRS domain SAG PF04092.8 KEP66966.1 - 1.5e-42 144.8 23.1 1.6e-25 89.9 6.5 2.1 2 0 0 2 2 2 2 SRS domain Dus PF01207.12 KEP66967.1 - 2.4e-27 95.6 3.6 5.8e-13 48.3 0.6 3.8 3 2 0 3 3 3 2 Dihydrouridine synthase (Dus) Apolipoprotein PF01442.13 KEP66968.1 - 0.0028 17.1 7.4 0.0092 15.5 4.2 2.3 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF4111 PF13427.1 KEP66968.1 - 0.098 12.5 0.1 0.94 9.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) OmpH PF03938.9 KEP66968.1 - 2.1 8.2 8.1 73 3.2 5.6 2.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4455 PF14643.1 KEP66970.1 - 9.6e-14 50.8 23.2 9.6e-14 50.8 16.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4455) Prominin PF05478.6 KEP66970.1 - 0.15 9.5 1.6 0.3 8.5 0.8 1.6 1 1 0 1 1 1 0 Prominin Alpha_adaptinC2 PF02883.15 KEP66971.1 - 4.8e-11 42.9 0.0 8.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 KEP66971.1 - 2e-08 34.1 0.0 3.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain LSM PF01423.17 KEP66973.1 - 6.6e-18 64.0 0.3 8.3e-18 63.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEP66973.1 - 0.00077 19.3 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Flag1_repress PF03614.8 KEP66973.1 - 0.077 12.5 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Hexapep PF00132.19 KEP66974.1 - 3.9e-09 35.6 2.0 0.029 13.8 0.9 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) BRF1 PF07741.8 KEP66975.1 - 0.71 10.1 3.6 0.87 9.8 2.5 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Dsh_C PF12316.3 KEP66975.1 - 5.2 7.1 10.1 5.7 6.9 7.0 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PDEase_I PF00233.14 KEP66976.1 - 2.3e-49 168.2 0.0 4.4e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Peptidase_M3 PF01432.15 KEP66978.1 - 6.8e-45 153.9 0.0 1e-20 74.2 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M3 Rav1p_C PF12234.3 KEP66979.1 - 0.14 10.3 0.0 0.14 10.2 0.0 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal Gly-zipper_OmpA PF13436.1 KEP66980.1 - 0.0033 17.0 7.1 0.0033 17.0 4.9 1.6 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 KEP66980.1 - 0.0067 16.5 15.0 0.014 15.5 10.4 1.4 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 KEP66980.1 - 0.052 13.2 19.0 0.087 12.4 13.2 1.3 1 0 0 1 1 1 0 Glycine zipper COMP PF11598.3 KEP66980.1 - 0.065 13.3 0.1 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein DUF3482 PF11981.3 KEP66980.1 - 0.082 12.1 2.0 0.13 11.4 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) TraT PF05818.7 KEP66980.1 - 0.098 12.0 4.9 0.16 11.4 3.4 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_YMGG PF13441.1 KEP66980.1 - 3.5 7.2 23.1 6.2 6.4 16.0 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 KEP66980.1 - 9.8 5.9 25.0 19 5.0 17.3 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain AP2 PF00847.15 KEP66982.1 - 3.8e-09 36.5 0.1 1.2e-08 34.9 0.1 1.9 1 0 0 1 1 1 1 AP2 domain Pox_MCEL PF03291.11 KEP66983.1 - 5.4e-34 117.5 0.0 2.6e-27 95.5 0.0 2.5 3 0 0 3 3 3 2 mRNA capping enzyme Methyltransf_11 PF08241.7 KEP66983.1 - 2.4e-08 34.3 0.1 6.7e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEP66983.1 - 1.2e-07 32.2 0.1 2.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEP66983.1 - 1.2e-07 31.9 0.4 3.7e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEP66983.1 - 4.9e-07 30.1 0.0 1.1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEP66983.1 - 2.7e-06 27.1 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEP66983.1 - 6.1e-06 26.2 0.2 1.6e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEP66983.1 - 2.1e-05 24.1 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEP66983.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KEP66983.1 - 0.23 10.5 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RNA_pol_Rpb2_6 PF00562.23 KEP66985.1 - 6.3e-112 374.1 0.0 1.2e-111 373.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEP66985.1 - 4.4e-44 149.8 0.0 6.5e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KEP66985.1 - 3.6e-28 97.6 0.1 1e-27 96.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KEP66985.1 - 3.5e-22 78.7 0.0 6.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KEP66985.1 - 4.6e-22 77.6 0.4 9.4e-22 76.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KEP66985.1 - 3.3e-20 71.6 0.0 5.9e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KEP66985.1 - 1.2e-10 41.1 0.2 2.4e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CTD_bind PF04818.8 KEP66986.1 - 0.12 12.5 0.0 0.4 10.9 0.0 1.9 1 1 0 1 1 1 0 RNA polymerase II-binding domain. Gluconate_2-dh3 PF13618.1 KEP66986.1 - 0.63 10.1 4.3 1.9 8.6 3.0 1.8 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF2870 PF11069.3 KEP66987.1 - 1 9.4 11.3 0.099 12.6 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) RRM_1 PF00076.17 KEP66988.1 - 1.1e-25 89.0 0.0 7.5e-13 47.9 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP66988.1 - 6.4e-21 74.1 0.0 4.8e-09 36.0 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP66988.1 - 6.9e-09 35.4 0.0 3.6e-05 23.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEP66988.1 - 0.006 16.3 0.0 8.4 6.2 0.0 3.2 2 1 1 3 3 3 2 Limkain b1 Rad51 PF08423.6 KEP66989.1 - 3.7e-129 429.1 0.1 5.7e-129 428.4 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KEP66989.1 - 1.8e-12 47.0 0.0 3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KEP66989.1 - 1.7e-09 37.1 0.0 2.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KEP66989.1 - 8.5e-06 25.0 0.0 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 KEP66989.1 - 1.2e-05 25.3 0.5 3.2e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.1 KEP66989.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3295 PF11702.3 KEP66990.1 - 0.17 10.8 1.4 0.21 10.5 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF485 PF04341.7 KEP66990.1 - 0.69 9.6 9.4 0.098 12.3 3.2 2.0 1 1 0 2 2 2 0 Protein of unknown function, DUF485 Cpn60_TCP1 PF00118.19 KEP66991.1 - 4.8e-144 480.5 9.7 5.4e-144 480.4 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KEP66991.1 - 0.07 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X His_Phos_1 PF00300.17 KEP66992.1 - 4.8e-39 133.9 0.0 6.8e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S17 PF00366.15 KEP66995.1 - 1.4e-11 44.3 0.2 1.8e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 RIIa PF02197.12 KEP66996.1 - 0.0013 18.1 0.1 0.0024 17.2 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Med2 PF11214.3 KEP66996.1 - 0.066 13.2 0.1 12 6.0 0.0 2.2 1 1 1 2 2 2 0 Mediator complex subunit 2 ArfGap PF01412.13 KEP66997.1 - 1.4e-30 105.4 0.1 2.5e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf AAA PF00004.24 KEP66998.1 - 4.6e-94 311.6 0.0 1.3e-46 158.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KEP66998.1 - 1.6e-24 85.6 0.3 3.9e-24 84.4 0.2 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KEP66998.1 - 4.2e-13 48.8 0.0 1.1e-05 24.6 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEP66998.1 - 2.3e-12 47.1 0.2 4.3e-05 23.6 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEP66998.1 - 2.4e-12 47.7 0.0 1.2e-05 26.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEP66998.1 - 7.8e-12 45.2 0.0 1.3e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEP66998.1 - 8.5e-12 45.4 2.1 0.00012 22.1 0.0 4.0 4 2 1 5 5 3 2 AAA ATPase domain AAA_5 PF07728.9 KEP66998.1 - 3.1e-11 43.1 0.1 1.4e-05 24.8 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEP66998.1 - 5e-11 42.8 0.0 1.6e-06 28.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 KEP66998.1 - 4.2e-09 36.3 0.0 0.00025 20.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KEP66998.1 - 1.3e-08 34.0 0.0 0.00087 18.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 KEP66998.1 - 1.8e-08 34.0 1.9 0.087 12.2 0.0 3.7 2 2 1 3 3 3 3 AAA domain Zeta_toxin PF06414.7 KEP66998.1 - 5.3e-08 32.2 0.0 0.0048 16.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 KEP66998.1 - 2.8e-07 30.9 0.0 0.019 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KEP66998.1 - 3.1e-07 30.5 0.0 0.013 15.6 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 KEP66998.1 - 5.4e-07 28.9 0.4 0.032 13.4 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEP66998.1 - 7e-07 28.9 1.7 0.017 14.8 0.4 2.9 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 KEP66998.1 - 1.1e-06 28.2 0.0 2.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.12 KEP66998.1 - 1.4e-06 27.8 0.0 0.048 13.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 KEP66998.1 - 3.7e-06 26.9 0.1 0.11 12.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain Sigma54_activ_2 PF14532.1 KEP66998.1 - 4.3e-06 26.8 0.0 0.034 14.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KEP66998.1 - 5e-06 26.3 0.0 0.041 13.5 0.0 3.2 2 2 1 3 3 3 2 Archaeal ATPase NACHT PF05729.7 KEP66998.1 - 8e-06 25.6 0.0 0.38 10.3 0.0 3.8 3 1 0 4 4 4 2 NACHT domain AAA_24 PF13479.1 KEP66998.1 - 3.8e-05 23.3 0.2 0.31 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 KEP66998.1 - 3.9e-05 22.8 0.2 2.6 7.1 0.0 3.4 2 1 1 3 3 3 1 KaiC ABC_tran PF00005.22 KEP66998.1 - 4.2e-05 23.8 0.0 0.26 11.5 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.13 KEP66998.1 - 5.1e-05 22.8 0.0 0.0072 15.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KEP66998.1 - 7.1e-05 22.7 0.0 0.0094 15.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 KEP66998.1 - 8.3e-05 21.5 0.1 0.28 9.9 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain Parvo_NS1 PF01057.12 KEP66998.1 - 0.00017 20.5 0.0 0.43 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 KEP66998.1 - 0.00019 21.2 0.1 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.21 KEP66998.1 - 0.00046 19.6 0.0 1.3 8.4 0.0 3.4 2 2 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.10 KEP66998.1 - 0.00061 19.5 0.3 1.5 8.5 0.0 3.6 2 1 0 3 3 3 1 NTPase PhoH PF02562.11 KEP66998.1 - 0.0013 17.9 0.2 1.1 8.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 KEP66998.1 - 0.0017 18.0 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEP66998.1 - 0.0019 17.1 0.0 0.9 8.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 KEP66998.1 - 0.002 17.7 0.0 0.96 9.0 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein SKI PF01202.17 KEP66998.1 - 0.003 17.4 0.1 4 7.2 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase CPSase_L_D3 PF02787.14 KEP66998.1 - 0.003 17.3 0.1 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Cytidylate_kin2 PF13189.1 KEP66998.1 - 0.004 17.0 0.0 0.49 10.2 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family UPF0079 PF02367.12 KEP66998.1 - 0.0048 16.5 0.1 5.5 6.6 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 KEP66998.1 - 0.0077 15.2 0.0 1 8.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 KEP66998.1 - 0.017 14.1 0.1 2.2 7.1 0.0 3.2 2 2 2 4 4 4 0 KAP family P-loop domain AAA_30 PF13604.1 KEP66998.1 - 0.019 14.5 0.0 8.3 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEP66998.1 - 0.02 14.3 0.7 6.6 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 KEP66998.1 - 0.041 14.2 0.0 7.5 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEP66998.1 - 0.069 12.6 0.0 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.24 KEP66998.1 - 0.089 12.2 0.0 20 4.5 0.0 3.2 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_11 PF13086.1 KEP66998.1 - 0.11 12.0 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KEP66998.1 - 0.12 11.5 0.0 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 KEP66998.1 - 0.13 11.7 0.4 6.4 6.1 0.1 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Rad17 PF03215.10 KEP66998.1 - 0.21 10.2 0.0 5.6 5.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_21 PF13304.1 KEP66998.1 - 0.66 9.8 1.3 28 4.5 0.0 3.2 4 0 0 4 4 3 0 AAA domain DNA_pol_A_exo1 PF01612.15 KEP66999.1 - 3.7e-20 72.1 0.0 6.1e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease SAG PF04092.8 KEP67000.1 - 5.7e-37 126.8 27.9 9.7e-25 87.3 5.7 2.2 1 1 1 2 2 2 2 SRS domain DcpS PF05652.7 KEP67000.1 - 0.061 13.7 0.2 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal SAG PF04092.8 KEP67001.1 - 4.3e-37 127.2 23.3 5.4e-25 88.1 5.1 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP67002.1 - 1.8e-25 89.7 6.2 2.7e-20 72.9 2.2 2.2 1 1 1 2 2 2 2 SRS domain Radical_SAM PF04055.16 KEP67003.1 - 1.8e-18 67.2 0.0 4.5e-18 65.9 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 KEP67003.1 - 1e-15 57.3 0.0 3.2e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 zf-C3HC4 PF00097.20 KEP67004.1 - 0.00024 20.6 9.1 0.00024 20.6 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEP67004.1 - 0.0022 17.8 8.6 0.0022 17.8 5.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KEP67004.1 - 0.027 14.2 6.0 0.054 13.2 3.9 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KEP67004.1 - 0.23 11.5 16.3 0.022 14.8 6.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP67004.1 - 0.53 10.0 13.3 0.078 12.7 6.2 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Solute_trans_a PF03619.11 KEP67006.1 - 2.3e-52 178.0 5.5 1.2e-48 165.8 1.2 2.4 2 0 0 2 2 2 2 Organic solute transporter Ostalpha P34-Arc PF04045.9 KEP67008.1 - 0.055 12.7 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc Mpv17_PMP22 PF04117.7 KEP67009.1 - 9.9e-15 53.9 4.8 9.9e-15 53.9 3.3 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family MoaE PF02391.12 KEP67015.1 - 4.5e-08 32.8 0.0 1.1e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 MoaE protein ABC_tran PF00005.22 KEP67016.1 - 1.7e-31 109.3 0.0 3.5e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KEP67016.1 - 2.1e-22 79.8 4.7 3.5e-22 79.1 3.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KEP67016.1 - 0.0003 20.1 0.0 0.0051 16.0 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KEP67016.1 - 0.00075 19.5 0.0 0.00075 19.5 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.1 KEP67016.1 - 0.0031 17.5 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEP67016.1 - 0.0038 17.5 0.0 0.0098 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 KEP67016.1 - 0.0044 16.8 1.8 0.0054 16.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_29 PF13555.1 KEP67016.1 - 0.0056 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KEP67016.1 - 0.012 16.4 0.0 0.039 14.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEP67016.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KEP67016.1 - 0.025 14.4 0.1 0.19 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KEP67016.1 - 0.034 13.5 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KEP67016.1 - 0.046 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Potyvirid-P3 PF13608.1 KEP67016.1 - 0.074 12.1 0.9 0.13 11.3 0.2 1.7 1 1 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF258 PF03193.11 KEP67016.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.18 KEP67016.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Adaptin_N PF01602.15 KEP67017.1 - 8e-88 295.0 0.2 9.8e-88 294.7 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KEP67017.1 - 1.6e-28 99.4 0.0 3.2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KEP67017.1 - 1.3e-10 41.4 12.1 0.00091 19.4 0.1 5.8 3 2 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KEP67017.1 - 0.00011 21.9 11.1 6 7.2 0.0 7.6 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 KEP67017.1 - 0.0035 17.8 10.5 0.061 13.8 0.1 5.7 4 1 1 5 5 5 1 HEAT-like repeat Ion_trans_2 PF07885.11 KEP67018.1 - 4.1e-11 42.4 1.4 9.5e-11 41.2 0.9 1.6 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 KEP67018.1 - 4.3e-10 39.4 0.1 3.8e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.26 KEP67018.1 - 2.4e-05 23.6 2.6 3.4e-05 23.2 1.3 1.6 1 1 0 1 1 1 1 Ion transport protein Mitochondr_Som1 PF11093.3 KEP67018.1 - 0.56 10.0 0.0 1.7 8.5 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DUF4044 PF13253.1 KEP67018.1 - 4.4 6.5 5.5 10 5.3 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Mito_carr PF00153.22 KEP67019.1 - 7.8e-55 182.5 4.0 3.7e-18 65.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein YiaAB PF05360.9 KEP67019.1 - 0.012 15.1 0.5 0.012 15.1 0.3 2.3 3 0 0 3 3 3 0 yiaA/B two helix domain Endonuclease_7 PF02945.10 KEP67020.1 - 0.0043 16.7 0.1 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 Recombination endonuclease VII COX16 PF14138.1 KEP67020.1 - 0.021 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF4427 PF14468.1 KEP67020.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) tRNA-synt_1b PF00579.20 KEP67021.1 - 7.5e-36 123.7 0.0 1.8e-17 63.4 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (W and Y) S4 PF01479.20 KEP67021.1 - 2e-07 30.3 0.2 5.2e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 S4 domain Methyltrans_SAM PF10672.4 KEP67022.1 - 2.2e-08 33.3 0.0 7.6e-06 24.9 0.0 2.2 2 0 0 2 2 2 2 S-adenosylmethionine-dependent methyltransferase Methyltransf_26 PF13659.1 KEP67022.1 - 2.2e-06 27.6 0.3 6.5e-06 26.1 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KEP67022.1 - 7.6e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 KEP67022.1 - 1.7e-05 24.3 0.0 8.7e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 MTS PF05175.9 KEP67022.1 - 0.0011 18.4 0.0 0.051 12.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KEP67022.1 - 0.013 16.0 0.0 0.23 12.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KEP67022.1 - 0.027 13.9 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KEP67022.1 - 0.25 10.3 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0051 PF01458.12 KEP67024.1 - 2.7e-45 154.6 0.0 5.9e-45 153.4 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein family (UPF0051) Paf67 PF10255.4 KEP67025.1 - 1.1e-128 429.5 13.6 1.4e-128 429.2 9.4 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Utp11 PF03998.8 KEP67026.1 - 0.11 12.2 31.6 0.13 12.0 21.9 1.0 1 0 0 1 1 1 0 Utp11 protein NFRKB_winged PF14465.1 KEP67026.1 - 0.92 9.3 3.0 0.75 9.6 0.3 2.1 2 1 1 3 3 3 0 NFRKB Winged Helix-like ECH PF00378.15 KEP67026.1 - 3 6.8 16.9 0.025 13.7 2.9 2.2 1 1 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family Trichoplein PF13868.1 KEP67027.1 - 8e-07 27.7 19.5 8e-07 27.7 13.5 2.8 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin DHC_N2 PF08393.8 KEP67028.1 - 1e-108 363.4 3.4 1.1e-108 363.3 0.0 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KEP67028.1 - 6.7e-98 326.8 0.1 1.6e-97 325.5 0.0 1.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 KEP67028.1 - 1.6e-10 40.8 0.6 0.0016 18.1 0.0 4.7 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEP67028.1 - 6.6e-06 26.9 4.4 0.04 14.7 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 KEP67028.1 - 0.0014 18.3 1.2 2.4 7.9 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA PF00004.24 KEP67028.1 - 0.0022 18.2 0.3 0.069 13.3 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEP67028.1 - 0.0045 17.3 0.0 4.1 7.7 0.0 3.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KEP67028.1 - 0.01 16.1 8.9 0.07 13.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain DUF853 PF05872.7 KEP67028.1 - 0.047 12.0 1.1 0.089 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) HemY_N PF07219.8 KEP67028.1 - 0.082 12.4 0.1 0.082 12.4 0.1 2.2 2 0 0 2 2 2 0 HemY protein N-terminus TPR_8 PF13181.1 KEP67028.1 - 0.12 12.1 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_28 PF13521.1 KEP67028.1 - 0.74 9.7 9.6 4 7.3 0.1 4.2 5 0 0 5 5 5 0 AAA domain Dynein_heavy PF03028.10 KEP67029.1 - 7.2e-212 705.2 0.0 1.3e-211 704.3 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 KEP67029.1 - 9.2e-54 182.4 10.6 1.7e-53 181.5 7.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 KEP67029.1 - 1.2e-50 171.5 0.0 8.6e-50 168.6 0.0 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KEP67029.1 - 2.4e-47 161.1 1.3 2.8e-42 144.5 0.1 3.5 3 1 0 3 3 3 2 P-loop containing dynein motor region D4 AAA_7 PF12775.2 KEP67029.1 - 7.7e-37 126.8 0.0 1.6e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 KEP67029.1 - 1.3e-06 28.2 0.0 8e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KEP67029.1 - 0.0019 17.6 0.7 0.0068 15.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Filament PF00038.16 KEP67029.1 - 0.0024 17.3 6.3 0.0024 17.3 4.4 3.6 3 1 1 4 4 4 1 Intermediate filament protein AAA PF00004.24 KEP67029.1 - 0.011 15.9 0.0 0.033 14.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Myosin_tail_1 PF01576.14 KEP67029.1 - 0.018 12.7 20.6 0.13 10.0 4.1 2.2 2 0 0 2 2 2 0 Myosin tail AAA_22 PF13401.1 KEP67029.1 - 0.046 13.8 0.7 0.53 10.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KEP67029.1 - 0.32 10.7 4.8 0.85 9.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Sec8_exocyst PF04048.9 KEP67029.1 - 3.3 7.3 11.6 0.46 10.1 0.2 3.9 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Gln-synt_C PF00120.19 KEP67030.1 - 1.3e-92 309.5 0.0 1.7e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KEP67030.1 - 2.7e-22 78.1 0.5 4.8e-22 77.3 0.3 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain TPR_1 PF00515.23 KEP67031.1 - 1.3e-74 242.9 32.2 3.6e-09 35.8 0.1 11.0 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 KEP67031.1 - 4.9e-73 240.7 50.6 8.8e-13 47.7 0.1 7.7 3 1 6 9 9 9 9 TPR repeat TPR_12 PF13424.1 KEP67031.1 - 1.2e-62 207.7 41.0 4.8e-11 42.4 0.4 7.0 1 1 9 10 10 10 10 Tetratricopeptide repeat TPR_17 PF13431.1 KEP67031.1 - 6.3e-60 194.4 38.2 5.9e-08 32.3 0.0 11.6 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 KEP67031.1 - 8.9e-58 187.6 23.6 1.8e-07 30.5 0.0 10.8 10 0 0 10 10 10 9 Tetratricopeptide repeat Glyco_transf_41 PF13844.1 KEP67031.1 - 3.6e-47 160.3 0.0 9.7e-23 79.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_8 PF13181.1 KEP67031.1 - 1.9e-39 130.4 14.7 5.3e-06 25.8 0.0 10.4 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEP67031.1 - 6e-38 128.7 13.1 9.2e-08 32.5 0.2 7.6 5 3 3 8 8 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 KEP67031.1 - 7.8e-32 106.5 15.2 0.00019 20.9 0.0 12.1 11 1 1 12 12 12 8 Tetratricopeptide repeat TPR_14 PF13428.1 KEP67031.1 - 4.1e-30 101.5 12.1 0.0048 17.4 0.0 11.0 3 2 9 12 12 11 8 Tetratricopeptide repeat TPR_10 PF13374.1 KEP67031.1 - 1.5e-28 97.8 32.9 0.0033 17.3 0.0 11.7 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_19 PF14559.1 KEP67031.1 - 5.8e-23 81.0 15.5 0.00011 22.4 0.0 8.2 4 3 4 8 8 8 6 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 KEP67031.1 - 3.5e-15 55.9 13.5 2.6e-05 23.5 0.0 4.9 3 1 1 4 4 4 3 Est1 DNA/RNA binding domain TPR_6 PF13174.1 KEP67031.1 - 4.5e-10 39.3 7.1 0.52 10.8 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEP67031.1 - 1.1e-09 37.9 5.5 0.32 10.8 0.0 5.4 3 1 2 6 6 6 4 Tetratricopeptide repeat Coatomer_E PF04733.9 KEP67031.1 - 1.3e-08 34.3 3.5 0.025 13.7 0.4 3.9 1 1 2 4 4 4 2 Coatomer epsilon subunit NARP1 PF12569.3 KEP67031.1 - 1.4e-07 30.6 4.1 0.51 9.0 0.1 4.1 1 1 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 KEP67031.1 - 4.2e-06 26.0 3.6 0.22 10.5 0.0 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 KEP67031.1 - 5.3e-06 26.3 0.1 8.5 7.1 0.0 6.6 9 0 0 9 9 5 0 Tetratricopeptide repeat TPR_5 PF12688.2 KEP67031.1 - 0.00041 20.3 2.2 0.032 14.2 0.0 3.4 3 1 0 3 3 3 1 Tetratrico peptide repeat TOM20_plant PF06552.7 KEP67031.1 - 0.0038 16.8 1.1 0.67 9.5 0.4 3.9 1 1 3 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 Glyco_trans_1_4 PF13692.1 KEP67031.1 - 0.0063 16.6 0.1 0.039 14.1 0.0 2.5 3 0 0 3 3 1 1 Glycosyl transferases group 1 Fis1_TPR_C PF14853.1 KEP67031.1 - 0.0068 16.2 4.5 2.1 8.2 0.0 4.5 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.4 KEP67031.1 - 0.029 14.1 0.0 2 8.2 0.0 3.3 3 1 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region MIT PF04212.13 KEP67031.1 - 0.6 10.0 16.9 1.5 8.7 0.1 6.7 7 2 1 8 8 7 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 KEP67031.1 - 4.3 7.6 11.2 16 5.7 0.3 4.5 3 1 2 5 5 5 0 Bacterial transcriptional activator domain PCI PF01399.22 KEP67033.1 - 1.3e-11 44.6 0.0 3.5e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain Cyt-b5 PF00173.23 KEP67034.1 - 1.4e-12 47.2 0.0 2.1e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ubiquitin PF00240.18 KEP67034.1 - 0.039 13.3 0.0 0.74 9.2 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin family PSS PF03034.10 KEP67035.1 - 1.6e-58 198.3 13.3 2.3e-58 197.8 9.2 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF2985 PF11204.3 KEP67035.1 - 2 8.2 11.2 0.61 9.8 0.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2985) O-FucT PF10250.4 KEP67036.1 - 1.7e-28 99.7 0.1 1.1e-14 54.3 0.0 3.4 3 1 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase Kinesin PF00225.18 KEP67037.1 - 2.1e-92 309.4 0.2 4e-92 308.4 0.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain Spc7 PF08317.6 KEP67037.1 - 0.00052 18.7 4.4 0.00052 18.7 3.0 4.3 4 0 0 4 4 4 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KEP67037.1 - 0.43 9.7 4.8 0.23 10.5 0.5 2.3 2 1 2 4 4 4 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 KEP67037.1 - 8.4 4.1 27.2 0.43 8.3 5.6 2.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3510 PF12022.3 KEP67038.1 - 6.1e-15 55.4 0.0 1.6e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.6 KEP67038.1 - 3e-05 23.8 1.3 3e-05 23.8 0.9 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Toxin_50 PF15530.1 KEP67038.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 50 UPF0560 PF10577.4 KEP67040.1 - 5 5.2 16.2 5.9 5.0 11.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF229 PF02995.12 KEP67040.1 - 10 4.4 14.1 12 4.1 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DnaJ PF00226.26 KEP67042.1 - 2.2e-21 75.3 0.4 3.6e-21 74.6 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain CfAFP PF05264.6 KEP67045.1 - 0.0026 17.5 0.1 0.0081 15.9 0.1 1.8 1 0 0 1 1 1 1 Choristoneura fumiferana antifreeze protein (CfAFP) Pkinase PF00069.20 KEP67046.1 - 8.2e-48 162.8 0.0 1.2e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67046.1 - 1.1e-28 100.0 0.0 1.4e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sds3 PF08598.6 KEP67046.1 - 0.025 14.1 0.6 6.2 6.2 0.1 2.2 2 0 0 2 2 2 0 Sds3-like Kinase-like PF14531.1 KEP67046.1 - 0.041 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PH_6 PF15406.1 KEP67047.1 - 0.048 13.7 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Glyco_hydro_3_C PF01915.17 KEP67047.1 - 0.11 11.9 3.2 0.043 13.3 0.6 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain DUF4475 PF14753.1 KEP67048.1 - 1.4e-05 24.7 0.2 2.4e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) Patatin PF01734.17 KEP67049.1 - 6.3e-08 32.7 1.4 2.4e-07 30.8 0.9 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Thiolase_N PF00108.18 KEP67050.1 - 2.1e-81 272.8 0.9 3.3e-81 272.1 0.2 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEP67050.1 - 1.3e-49 166.7 0.1 3e-49 165.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KEP67050.1 - 0.00012 21.6 0.1 0.00039 19.9 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KEP67050.1 - 0.00098 19.0 0.0 0.006 16.5 0.0 2.4 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF4483 PF14825.1 KEP67051.1 - 4.5e-25 88.5 4.8 1.6e-23 83.4 3.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4483) ATP_sub_h PF10775.4 KEP67051.1 - 0.037 13.7 0.3 0.36 10.6 0.1 2.4 2 0 0 2 2 2 0 ATP synthase complex subunit h HDOD PF08668.7 KEP67051.1 - 0.067 12.4 0.1 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 HDOD domain HSP70 PF00012.15 KEP67052.1 - 1.2e-274 911.8 4.3 1.4e-274 911.6 3.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEP67052.1 - 1.2e-14 53.6 0.3 9.7e-13 47.3 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KEP67052.1 - 9.9e-05 22.0 0.0 0.00034 20.2 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KEP67052.1 - 0.0017 17.2 0.9 0.3 9.8 0.2 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KEP67052.1 - 0.0066 15.5 0.1 0.031 13.3 0.1 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 KEP67052.1 - 0.024 14.4 3.0 0.62 9.9 0.0 3.2 2 1 0 2 2 2 0 Cell division protein FtsA NICE-3 PF07406.6 KEP67052.1 - 0.2 11.1 1.3 0.38 10.2 0.9 1.4 1 0 0 1 1 1 0 NICE-3 protein SNF2_N PF00176.18 KEP67055.1 - 6.4e-19 67.8 0.0 1.2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.18 KEP67055.1 - 2.3e-10 40.1 0.9 6.8e-10 38.6 0.6 1.8 1 0 0 1 1 1 1 HNH endonuclease zf-C4_Topoisom PF01396.14 KEP67055.1 - 5.7e-08 32.1 1.5 1.4e-07 30.8 1.0 1.7 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger ResIII PF04851.10 KEP67055.1 - 0.0032 17.3 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEP67055.1 - 0.0085 15.9 1.0 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1649 PF07855.7 KEP67056.1 - 8.8e-14 51.4 0.0 1.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1649) WD40 PF00400.27 KEP67057.1 - 4.4e-10 39.0 17.8 8.1e-08 31.8 0.2 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Urb2 PF10441.4 KEP67057.1 - 0.86 9.1 0.5 6.9 6.1 0.3 2.3 2 0 0 2 2 2 0 Urb2/Npa2 family Nucleoside_tran PF01733.13 KEP67058.1 - 7.9e-16 58.0 1.4 7.9e-16 58.0 1.0 2.6 2 1 1 3 3 3 2 Nucleoside transporter Brix PF04427.13 KEP67062.1 - 3.4e-37 127.9 0.0 5.1e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain Nucleoporin_FG PF13634.1 KEP67063.1 - 1.5e-16 60.6 206.7 1.5e-06 28.3 27.6 6.0 2 2 2 4 4 4 3 Nucleoporin FG repeat region Nsp1_C PF05064.8 KEP67063.1 - 2.1e-13 49.9 0.3 4.9e-13 48.7 0.2 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region SNF2_N PF00176.18 KEP67065.1 - 4.8e-78 261.9 0.2 7.3e-78 261.3 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP67065.1 - 2.8e-15 55.9 0.0 1.1e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP67065.1 - 1.8e-07 30.7 0.0 4.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KEP67065.1 - 2.3e-07 29.9 0.0 2.6e-06 26.5 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KEP67065.1 - 8.8e-06 25.6 0.0 8.8e-06 25.6 0.0 2.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DUF1115 PF06544.7 KEP67065.1 - 0.083 12.5 1.5 5.6 6.6 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) FAST_1 PF06743.10 KEP67066.1 - 2.1e-05 24.1 0.2 4.6 7.0 0.0 3.9 2 1 1 3 3 3 3 FAST kinase-like protein, subdomain 1 RAP PF08373.5 KEP67066.1 - 0.0016 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain Arm PF00514.18 KEP67067.1 - 0.00053 19.7 2.5 0.4 10.5 0.0 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.3 KEP67067.1 - 0.091 12.4 0.5 0.3 10.8 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) UPF0175 PF03683.8 KEP67067.1 - 0.19 11.2 1.9 0.79 9.2 0.5 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0175) Aldo_ket_red PF00248.16 KEP67068.1 - 2.1e-40 138.3 0.0 3.1e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_binding_2 PF13380.1 KEP67068.1 - 0.01 15.9 0.0 5.9 7.0 0.0 3.3 3 0 0 3 3 3 0 CoA binding domain PRCC PF10253.4 KEP67068.1 - 0.93 10.1 5.5 37 4.9 0.0 2.4 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting SWIB PF02201.13 KEP67069.1 - 1.6e-24 85.3 0.1 2.3e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain Rep_fac_C PF08542.6 KEP67072.1 - 4.1e-09 36.3 0.1 9.2e-05 22.3 0.0 2.7 3 0 0 3 3 3 2 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KEP67072.1 - 1.4e-07 31.3 0.0 4.4e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 KEP67072.1 - 0.0014 18.6 0.1 0.0045 17.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 KEP67072.1 - 0.036 12.7 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Cpn10 PF00166.16 KEP67074.1 - 1.5e-35 121.0 0.0 8.3e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit CorA PF01544.13 KEP67076.1 - 5.5e-05 22.3 5.4 0.00024 20.2 3.8 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ldr_toxin PF13940.1 KEP67076.1 - 0.037 13.8 0.9 0.14 11.9 0.6 2.0 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system DUF1675 PF07897.6 KEP67076.1 - 0.11 12.3 0.5 0.23 11.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2231 PF09990.4 KEP67076.1 - 0.21 11.9 2.2 0.4 11.0 1.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) RskA PF10099.4 KEP67077.1 - 0.092 12.4 7.7 0.99 9.1 0.8 2.9 1 1 2 3 3 3 0 Anti-sigma-K factor rskA ETRAMP PF09716.5 KEP67077.1 - 0.096 12.6 0.3 0.26 11.2 0.0 1.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CD99L2 PF12301.3 KEP67077.1 - 4.5 6.9 7.2 0.28 10.8 0.2 2.1 2 1 0 2 2 2 0 CD99 antigen like protein 2 GHMP_kinases_N PF00288.21 KEP67077.1 - 5 7.2 8.5 7.6 6.6 0.1 3.1 3 1 0 3 3 3 0 GHMP kinases N terminal domain cobW PF02492.14 KEP67078.1 - 5.8e-28 97.5 0.0 1.4e-27 96.2 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KEP67078.1 - 0.099 12.3 0.0 0.9 9.3 0.0 2.6 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain UPF0079 PF02367.12 KEP67078.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF1517 PF07466.6 KEP67078.1 - 0.51 9.2 6.2 1 8.2 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) eIF-3c_N PF05470.7 KEP67081.1 - 0.069 11.2 3.9 0.16 10.0 2.7 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TFIIA PF03153.8 KEP67081.1 - 2 8.2 15.5 0.0076 16.1 2.7 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ashwin PF15323.1 KEP67082.1 - 0.012 15.6 0.3 0.038 13.9 0.2 1.8 1 0 0 1 1 1 0 Developmental protein Kinesin PF00225.18 KEP67083.1 - 1.8e-64 217.5 0.0 2.6e-58 197.3 0.0 2.0 2 0 0 2 2 2 2 Kinesin motor domain Mito_carr PF00153.22 KEP67087.1 - 1.4e-60 201.0 0.5 6.6e-20 70.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 KEP67087.1 - 0.053 13.4 0.0 4.3 7.3 0.0 2.9 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase ThiF PF00899.16 KEP67088.1 - 3.5e-08 33.3 0.0 7.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family PIH1 PF08190.7 KEP67089.1 - 2.1e-32 112.8 0.0 4.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 zf-Tim10_DDP PF02953.10 KEP67090.1 - 1.3e-08 34.0 1.1 1.5e-08 33.7 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Chalcone PF02431.10 KEP67091.1 - 0.00062 19.2 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Peptidase_M22 PF00814.20 KEP67092.1 - 4.9e-41 141.0 0.2 9.3e-21 74.5 0.1 5.5 5 1 0 5 5 5 5 Glycoprotease family RabGAP-TBC PF00566.13 KEP67094.1 - 3.2e-31 108.5 13.2 8.4e-31 107.1 0.2 3.4 4 0 0 4 4 4 2 Rab-GTPase-TBC domain RRM_1 PF00076.17 KEP67095.1 - 0.0018 17.8 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 KEP67095.1 - 0.0067 16.1 10.4 0.0067 16.1 7.2 2.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEP67095.1 - 0.038 13.6 13.3 0.11 12.1 9.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP67095.1 - 0.074 13.0 14.9 0.2 11.7 10.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEP67095.1 - 0.29 11.0 14.0 0.97 9.3 9.7 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEP67095.1 - 0.55 10.0 8.6 1.4 8.7 6.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 KEP67095.1 - 3.4 7.5 15.0 12 5.8 10.4 2.0 1 0 0 1 1 1 0 Ring finger domain Filament PF00038.16 KEP67097.1 - 0.00028 20.4 19.1 0.00029 20.4 8.4 2.2 2 0 0 2 2 2 2 Intermediate filament protein Vfa1 PF08432.5 KEP67097.1 - 2.3 8.1 11.3 4.8 7.1 0.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Tho2 PF11262.3 KEP67097.1 - 3.4 6.6 4.8 7.1 5.5 3.3 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1800 PF08811.6 KEP67097.1 - 5.4 5.8 12.7 0.29 10.0 4.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1800) APG6 PF04111.7 KEP67097.1 - 10 5.0 19.1 8.4 5.3 7.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Kinase-like PF14531.1 KEP67098.1 - 9.1e-07 28.1 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP67098.1 - 0.041 13.0 0.0 0.09 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.9 KEP67098.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hexapep PF00132.19 KEP67100.1 - 1.2e-09 37.2 6.4 0.0095 15.4 0.1 3.9 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 KEP67100.1 - 0.00024 20.9 0.4 0.00024 20.9 0.3 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.1 KEP67100.1 - 0.0038 16.7 9.6 0.13 11.8 0.5 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Gag_p12 PF01141.13 KEP67100.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 LRR_4 PF12799.2 KEP67102.1 - 1.9e-18 65.6 31.3 5.3e-07 29.1 4.8 5.0 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEP67102.1 - 6.7e-11 41.7 11.0 2.2e-05 24.0 5.3 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 KEP67102.1 - 2.7e-07 30.3 4.0 6.7e-06 25.7 2.5 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 KEP67102.1 - 7.4e-07 28.5 9.4 0.15 12.1 0.0 5.7 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 KEP67102.1 - 3.7e-05 23.2 5.7 7.5 7.2 0.0 6.2 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 KEP67102.1 - 0.00011 21.7 15.6 1.2 9.4 0.1 6.0 5 1 1 6 6 6 3 Leucine Rich Repeat CAF1 PF04857.15 KEP67103.1 - 4.6e-59 199.8 0.0 7.3e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 KEP67103.1 - 0.021 14.2 0.0 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease R3H PF01424.17 KEP67103.1 - 0.042 13.5 0.1 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 R3H domain zf-RING_2 PF13639.1 KEP67105.1 - 2.1e-11 43.4 13.5 4e-11 42.5 9.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEP67105.1 - 3e-06 26.7 7.2 5.8e-06 25.8 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEP67105.1 - 9.9e-06 25.4 8.8 1.9e-05 24.5 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP67105.1 - 1.4e-05 25.0 6.4 2.7e-05 24.1 4.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEP67105.1 - 0.028 14.1 10.4 0.054 13.2 7.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 KEP67105.1 - 0.03 14.1 6.1 0.062 13.1 4.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KEP67105.1 - 0.26 11.3 8.1 0.65 10.0 5.6 1.7 1 0 0 1 1 1 0 RING-variant domain Pkinase PF00069.20 KEP67106.1 - 1.1e-76 257.4 0.0 1.4e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67106.1 - 2.5e-41 141.4 0.0 3.4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP67106.1 - 5.4e-07 28.8 0.0 9.7e-07 28.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEP67106.1 - 0.0011 18.1 0.1 0.0017 17.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP67106.1 - 0.0035 17.1 0.2 0.14 11.8 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEP67106.1 - 0.0039 16.5 0.7 0.0072 15.7 0.5 1.3 1 0 0 1 1 1 1 RIO1 family KaiB PF07689.7 KEP67106.1 - 0.14 11.6 0.1 0.38 10.2 0.1 1.7 1 0 0 1 1 1 0 KaiB domain Choline_kinase PF01633.15 KEP67106.1 - 0.25 10.8 0.3 0.46 10.0 0.2 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF3926 PF13080.1 KEP67107.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Tim44 PF04280.10 KEP67107.1 - 0.023 14.6 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Tim44-like domain UPF0197 PF05251.7 KEP67109.1 - 0.59 10.4 0.1 1 9.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) Autophagy_Cterm PF10381.4 KEP67109.1 - 0.6 9.2 0.1 0.96 8.6 0.1 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal tRNA-synt_1d PF00750.14 KEP67110.1 - 8.7e-45 153.0 0.0 7.2e-22 77.6 0.0 4.1 4 0 0 4 4 4 4 tRNA synthetases class I (R) DALR_1 PF05746.10 KEP67110.1 - 6.4e-21 74.5 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KEP67110.1 - 2.4e-05 24.7 0.0 0.00027 21.4 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF688 PF05097.7 KEP67111.1 - 0.019 13.9 4.6 0.024 13.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) PCAF_N PF06466.6 KEP67111.1 - 0.071 12.4 0.2 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain GatB_N PF02934.10 KEP67112.1 - 3.4e-84 282.1 0.0 3.5e-75 252.5 0.0 3.7 2 1 0 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KEP67112.1 - 7.3e-13 48.4 0.0 2e-05 24.3 0.0 3.2 3 0 0 3 3 3 3 GatB domain DUF4612 PF15389.1 KEP67113.1 - 0.092 13.3 2.6 0.2 12.2 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) DNA_pol_E_B PF04042.11 KEP67114.1 - 3.4e-30 104.8 0.0 4.7e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Sel1 PF08238.7 KEP67115.1 - 3.2e-05 24.3 25.7 0.018 15.7 0.8 6.9 7 0 0 7 7 7 3 Sel1 repeat Pkinase PF00069.20 KEP67116.1 - 2.7e-66 223.3 0.0 3.6e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67116.1 - 7.1e-29 100.6 0.0 1.1e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEP67116.1 - 0.072 12.8 1.0 1.1 8.8 0.4 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEP67116.1 - 0.098 11.7 0.0 0.33 9.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RHH_1 PF01402.16 KEP67117.1 - 0.059 13.2 0.5 1 9.3 0.0 2.9 2 1 0 2 2 2 0 Ribbon-helix-helix protein, copG family Milton PF12448.3 KEP67118.1 - 0.11 12.7 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Kinesin associated protein E1-E2_ATPase PF00122.15 KEP67119.1 - 2.2e-54 183.9 0.0 1e-53 181.7 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEP67119.1 - 5.2e-44 149.9 1.5 3.1e-43 147.4 0.3 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEP67119.1 - 1.1e-21 78.2 0.0 4.4e-20 73.0 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP67119.1 - 1.8e-14 53.4 0.0 3.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEP67119.1 - 4.5e-12 46.5 0.0 2.8e-11 43.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEP67119.1 - 1.3e-06 27.8 0.0 7.8e-06 25.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEP67119.1 - 5.8e-06 26.0 0.5 0.00011 21.9 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GpcrRhopsn4 PF10192.4 KEP67120.1 - 3e-18 65.9 2.2 5.1e-18 65.1 1.5 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 KEP67120.1 - 0.037 12.9 1.4 0.068 12.1 1.0 1.4 1 0 0 1 1 1 0 Lung seven transmembrane receptor RNA_pol_Rpb8 PF03870.10 KEP67122.1 - 1.2e-34 119.4 0.1 1.3e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Sulfate_transp PF00916.15 KEP67123.1 - 1.2e-27 96.6 15.4 3.4e-18 65.6 1.1 3.0 2 1 1 3 3 3 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEP67123.1 - 6e-13 48.2 2.1 2.9e-12 46.0 1.4 2.2 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif Peptidase_M50 PF02163.17 KEP67123.1 - 0.067 12.1 0.0 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M50 CS PF04969.11 KEP67125.1 - 1.4e-17 63.9 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 KEP67125.1 - 2.6e-14 52.8 0.2 5e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. IncA PF04156.9 KEP67127.1 - 0.0018 17.9 4.7 0.0033 17.0 3.3 1.4 1 0 0 1 1 1 1 IncA protein HTH_Tnp_IS1 PF12759.2 KEP67127.1 - 0.12 11.8 0.9 0.38 10.2 0.5 1.9 2 0 0 2 2 2 0 InsA C-terminal domain TMF_TATA_bd PF12325.3 KEP67127.1 - 0.34 10.6 4.8 0.88 9.3 3.3 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.7 KEP67127.1 - 0.37 9.1 10.2 0.69 8.2 7.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlgN PF05130.7 KEP67127.1 - 1.1 9.4 8.4 2.2 8.5 5.8 1.4 1 0 0 1 1 1 0 FlgN protein Tropomyosin_1 PF12718.2 KEP67127.1 - 1.4 8.7 10.0 0.12 12.2 0.4 2.5 3 0 0 3 3 3 0 Tropomyosin like Ctr PF04145.10 KEP67127.1 - 6.9 6.7 6.7 1.2e+02 2.6 4.7 2.7 1 1 0 1 1 1 0 Ctr copper transporter family Polyketide_cyc PF03364.15 KEP67128.1 - 7.2e-19 68.0 0.0 2e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KEP67128.1 - 1.8e-05 24.9 4.1 0.0099 16.0 0.1 3.5 3 0 0 3 3 3 2 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.11 KEP67129.1 - 2.8e-20 72.3 33.4 2.8e-20 72.3 23.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily OB_NTP_bind PF07717.11 KEP67131.1 - 1.8e-28 98.6 0.1 3.7e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEP67131.1 - 1.2e-25 89.4 0.1 1.2e-25 89.4 0.1 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEP67131.1 - 3.4e-11 42.8 0.0 7.7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP67131.1 - 7.7e-10 38.5 0.2 3.5e-09 36.3 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEP67131.1 - 1.8e-05 24.8 0.0 6.8e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KEP67131.1 - 0.00024 21.0 0.7 0.11 12.3 0.1 2.6 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KEP67131.1 - 0.00091 19.0 0.3 0.003 17.3 0.2 1.8 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_30 PF13604.1 KEP67131.1 - 0.0016 18.0 0.7 0.0022 17.6 0.0 1.5 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 KEP67131.1 - 0.0048 17.1 0.4 0.15 12.3 0.3 2.5 1 1 0 1 1 1 1 ABC transporter T2SE PF00437.15 KEP67131.1 - 0.0052 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 KEP67131.1 - 0.0073 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 KEP67131.1 - 0.016 14.5 0.0 0.29 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEP67131.1 - 0.018 14.4 0.1 0.58 9.5 0.0 2.5 2 1 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 KEP67131.1 - 0.023 13.7 0.0 0.05 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.17 KEP67131.1 - 0.024 14.0 0.4 0.066 12.6 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KEP67131.1 - 0.031 13.9 0.5 0.084 12.5 0.3 1.9 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 KEP67131.1 - 0.04 13.9 0.1 0.14 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KEP67131.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 KEP67131.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_29 PF13555.1 KEP67131.1 - 0.075 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KEP67131.1 - 0.087 11.6 0.0 0.33 9.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 KEP67131.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRPRB PF09439.5 KEP67131.1 - 0.15 11.2 0.0 0.93 8.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.12 KEP67131.1 - 0.17 11.3 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein TIM PF00121.13 KEP67132.1 - 6.8e-85 284.0 0.0 8e-85 283.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase SAG PF04092.8 KEP67134.1 - 8e-40 136.0 0.4 5.6e-19 68.7 0.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP67136.1 - 6.9e-44 149.1 10.0 1.2e-21 77.4 1.7 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP67137.1 - 1.5e-27 96.4 0.1 1.6e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 SRS domain YbjQ_1 PF01906.12 KEP67138.1 - 0.00053 20.3 0.0 0.24 11.8 0.0 4.0 4 1 0 4 4 4 1 Putative heavy-metal-binding Sof1 PF04158.9 KEP67139.1 - 8.3e-29 99.4 12.4 8.3e-29 99.4 8.6 1.6 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.27 KEP67139.1 - 5.2e-25 86.3 16.5 2e-08 33.7 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat NBP1 PF08537.5 KEP67140.1 - 0.07 12.3 0.4 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 PSD1 PF07587.6 KEP67140.1 - 0.16 11.3 4.4 0.24 10.7 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) DUF932 PF06067.6 KEP67140.1 - 0.3 10.3 4.8 0.15 11.3 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF932) AAA_18 PF13238.1 KEP67141.1 - 2.9e-28 98.7 0.1 3.9e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEP67141.1 - 9.5e-16 58.7 0.1 1.4e-15 58.1 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEP67141.1 - 2.7e-07 30.5 0.2 7e-05 22.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KEP67141.1 - 0.0001 22.4 0.1 0.00018 21.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KEP67141.1 - 0.0001 22.4 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KEP67141.1 - 0.00016 21.6 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 KEP67141.1 - 0.00018 21.3 0.0 0.002 18.0 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_14 PF13173.1 KEP67141.1 - 0.00035 20.4 0.4 0.0016 18.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 KEP67141.1 - 0.00071 19.3 0.4 0.0014 18.3 0.1 1.6 2 0 0 2 2 2 1 NTPase FtsK_SpoIIIE PF01580.13 KEP67141.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family SKI PF01202.17 KEP67141.1 - 0.0016 18.2 0.4 0.048 13.5 0.3 2.4 1 1 0 1 1 1 1 Shikimate kinase AAA_10 PF12846.2 KEP67141.1 - 0.0025 17.2 0.3 0.023 14.1 0.0 2.1 1 1 0 2 2 2 1 AAA-like domain KTI12 PF08433.5 KEP67141.1 - 0.0033 16.6 0.0 0.0071 15.5 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 KaiC PF06745.8 KEP67141.1 - 0.0037 16.4 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.12 KEP67141.1 - 0.0045 16.4 0.0 0.015 14.6 0.0 1.9 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KEP67141.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KEP67141.1 - 0.0055 16.8 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 KEP67141.1 - 0.0064 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KEP67141.1 - 0.0071 16.0 0.1 0.02 14.5 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 KEP67141.1 - 0.01 16.3 0.0 0.016 15.6 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein Viral_helicase1 PF01443.13 KEP67141.1 - 0.011 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 KEP67141.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain MOSC PF03473.12 KEP67141.1 - 0.013 14.9 0.1 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 MOSC domain ATP_bind_1 PF03029.12 KEP67141.1 - 0.017 14.6 0.2 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KEP67141.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEP67141.1 - 0.041 13.5 0.0 0.09 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEP67141.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KEP67141.1 - 0.046 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 KEP67141.1 - 0.047 13.3 0.3 0.2 11.2 0.1 2.0 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 KEP67141.1 - 0.055 12.4 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 KEP67141.1 - 0.065 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein SRP54 PF00448.17 KEP67141.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_3 PF07726.6 KEP67141.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTF2 PF02136.15 KEP67146.1 - 2e-30 105.6 0.0 2.2e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain NAGLU PF05089.7 KEP67146.1 - 0.091 11.5 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Mtr2 PF10429.4 KEP67146.1 - 0.095 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 MCM_bind PF09739.4 KEP67147.1 - 2.3e-13 49.7 0.2 6.6e-07 28.9 0.0 2.4 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 KEP67147.1 - 7.5e-10 38.9 0.1 3e-09 37.0 0.1 2.0 1 1 0 1 1 1 1 Putative alanine racemase V_ATPase_I PF01496.14 KEP67147.1 - 1.2 6.8 1.5 1.7 6.3 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Radial_spoke PF04712.7 KEP67148.1 - 2.6e-98 329.9 0.3 3.8e-98 329.3 0.2 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein Inositol_P PF00459.20 KEP67149.1 - 6.4e-12 45.3 0.0 3e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Inositol monophosphatase family Sad1_UNC PF07738.8 KEP67150.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Peptidase_M24 PF00557.19 KEP67151.1 - 4.2e-52 176.7 0.2 1.5e-50 171.6 0.0 2.2 2 0 0 2 2 2 2 Metallopeptidase family M24 AMP_N PF05195.11 KEP67151.1 - 5.9e-15 54.8 0.1 3.1e-14 52.5 0.1 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain CRAL_TRIO_2 PF13716.1 KEP67152.1 - 5.2e-24 84.8 0.3 8.5e-24 84.1 0.2 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 KEP67152.1 - 3e-14 52.8 0.0 7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DUF966 PF06136.8 KEP67152.1 - 0.16 11.3 12.8 0.21 10.9 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF755 PF05501.6 KEP67152.1 - 3.1 7.8 33.9 1.5 8.9 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) MORN PF02493.15 KEP67155.1 - 4.3e-08 32.4 23.4 0.0022 17.5 1.9 6.6 6 0 0 6 6 6 3 MORN repeat MMR_HSR1 PF01926.18 KEP67156.1 - 7.8e-18 64.5 0.0 1.6e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KEP67156.1 - 8.1e-15 54.4 0.0 1.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KEP67156.1 - 1.7e-10 40.3 0.0 2.8e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEP67156.1 - 1.2e-07 31.6 0.1 0.0019 18.0 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KEP67156.1 - 0.001 19.5 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 KEP67156.1 - 0.0022 17.1 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KEP67156.1 - 0.0053 16.2 0.2 5.4 6.4 0.1 3.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 KEP67156.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KEP67156.1 - 0.021 13.5 0.3 0.24 10.1 0.0 2.4 2 1 1 3 3 3 0 ArgK protein MCM PF00493.18 KEP67156.1 - 0.027 13.3 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_33 PF13671.1 KEP67156.1 - 0.03 14.1 0.8 2 8.2 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 KEP67156.1 - 0.033 14.1 0.1 0.064 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 KEP67156.1 - 0.034 13.3 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KEP67156.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 COPI_C PF06957.6 KEP67157.1 - 5.9 5.3 12.0 11 4.4 8.3 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus RRM_1 PF00076.17 KEP67158.1 - 1.1e-18 66.5 0.3 1.7e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67158.1 - 6.6e-14 51.6 0.1 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67158.1 - 1.3e-10 40.9 0.0 1.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEP67158.1 - 0.0049 16.5 0.0 0.0089 15.7 0.0 1.6 1 1 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 KEP67158.1 - 0.075 12.8 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 RNA binding motif RYDR_ITPR PF01365.16 KEP67159.1 - 0.31 10.2 0.1 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 RIH domain Baculo_11_kDa PF06143.6 KEP67160.1 - 0.0087 15.4 0.4 0.02 14.2 0.3 1.5 1 0 0 1 1 1 1 Baculovirus 11 kDa family Urm1 PF09138.6 KEP67161.1 - 5.9e-17 61.5 0.0 7.7e-14 51.5 0.0 2.2 2 1 0 2 2 2 2 Urm1 (Ubiquitin related modifier) SKIP_SNW PF02731.10 KEP67162.1 - 1.2e-63 213.3 4.8 1.2e-63 213.3 3.3 2.6 3 0 0 3 3 3 1 SKIP/SNW domain Peptidase_S28 PF05577.7 KEP67162.1 - 0.069 11.7 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF2756 PF10956.3 KEP67162.1 - 1.8 8.8 10.2 1.8 8.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2756) DUF3633 PF12315.3 KEP67163.1 - 8e-11 41.6 0.0 2.1e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3633) DUF3726 PF12525.3 KEP67163.1 - 0.032 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) GAD PF02938.9 KEP67163.1 - 0.082 13.0 0.1 1 9.5 0.0 2.5 3 0 0 3 3 3 0 GAD domain HTH_23 PF13384.1 KEP67165.1 - 2.4e-06 27.0 0.1 1e-05 24.9 0.1 2.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.1 KEP67165.1 - 0.011 15.2 0.2 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF1366 PF07104.6 KEP67167.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) dUTPase PF00692.14 KEP67168.1 - 3.3e-16 58.9 0.0 1.6e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 dUTPase Nucleoside_tran PF01733.13 KEP67169.1 - 6.9e-26 91.1 3.6 1e-24 87.3 2.5 2.2 1 1 0 1 1 1 1 Nucleoside transporter RsbU_N PF08673.5 KEP67169.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain DUF1517 PF07466.6 KEP67169.1 - 1.2 8.0 6.0 0.52 9.2 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) AP2 PF00847.15 KEP67170.1 - 2.3e-29 101.3 52.5 4.7e-07 29.8 2.7 7.7 8 0 0 8 8 8 6 AP2 domain Nop14 PF04147.7 KEP67170.1 - 9.5 3.9 8.7 15 3.3 6.0 1.2 1 0 0 1 1 1 0 Nop14-like family IMPDH PF00478.20 KEP67171.1 - 4e-133 443.6 0.1 6.9e-117 390.2 0.0 2.0 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KEP67171.1 - 4.6e-15 55.1 0.2 2.5e-08 33.5 0.0 3.1 3 0 0 3 3 3 2 CBS domain NMO PF03060.10 KEP67171.1 - 7e-13 48.4 7.1 8e-08 31.7 2.7 2.9 2 1 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 KEP67171.1 - 1.2e-10 40.7 1.1 1.2e-10 40.7 0.8 1.9 3 0 0 3 3 3 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KEP67171.1 - 1.4e-06 27.8 1.4 0.0019 17.4 0.1 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 KEP67171.1 - 1.4e-05 24.3 1.6 3.3e-05 23.1 0.4 2.1 1 1 2 3 3 3 1 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.1 KEP67171.1 - 0.019 14.1 0.2 0.069 12.3 0.1 1.9 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase PcrB PF01884.12 KEP67171.1 - 0.03 13.5 2.0 15 4.7 0.0 3.4 2 1 1 3 3 3 0 PcrB family Trp_syntA PF00290.15 KEP67171.1 - 0.049 12.1 0.7 0.29 9.6 0.0 2.4 2 1 1 3 3 3 0 Tryptophan synthase alpha chain DHO_dh PF01180.16 KEP67171.1 - 0.071 12.0 0.2 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.12 KEP67171.1 - 0.09 11.8 1.1 0.52 9.3 0.2 2.3 1 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI Band_7 PF01145.20 KEP67172.1 - 3.2e-24 85.8 0.1 5e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family XPG_N PF00752.12 KEP67173.1 - 4.8e-22 78.1 0.0 8.8e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KEP67173.1 - 1.5e-21 76.1 0.1 3.3e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 KEP67173.1 - 3.4e-07 30.0 0.2 8.6e-07 28.6 0.1 1.7 1 0 0 1 1 1 1 XPG domain containing Pox_G5 PF04599.7 KEP67173.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein GCFC PF07842.7 KEP67174.1 - 8.6e-40 136.8 16.6 1.3e-36 126.4 6.5 3.0 4 0 0 4 4 4 2 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KEP67174.1 - 4.9e-11 42.2 1.4 2.1e-10 40.2 0.9 2.2 1 0 0 1 1 1 1 G-patch domain CobA_CobO_BtuR PF02572.10 KEP67174.1 - 0.93 9.0 8.8 0.52 9.9 4.1 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PDEase_I PF00233.14 KEP67175.1 - 9.2e-51 172.8 0.0 1.3e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF463 PF04317.7 KEP67177.1 - 0.017 13.7 0.3 0.86 8.1 0.0 2.3 2 0 0 2 2 2 0 YcjX-like family, DUF463 PDEase_I PF00233.14 KEP67178.1 - 1.6e-35 123.0 2.2 2.6e-35 122.2 1.5 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KEP67178.1 - 0.00068 19.6 0.1 0.0019 18.2 0.1 1.8 1 0 0 1 1 1 1 HD domain Not3 PF04065.10 KEP67180.1 - 3.7e-78 261.9 19.9 4.9e-78 261.6 13.8 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KEP67180.1 - 1.5e-38 131.6 6.0 3.5e-38 130.5 4.2 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Med3 PF11593.3 KEP67180.1 - 0.00065 19.0 1.0 0.002 17.4 0.0 2.2 1 1 1 2 2 2 1 Mediator complex subunit 3 fungal T4SS PF07996.6 KEP67180.1 - 0.075 12.8 0.5 0.16 11.7 0.2 1.6 1 1 0 1 1 1 0 Type IV secretion system proteins Pkinase PF00069.20 KEP67181.1 - 4.4e-71 239.0 0.0 6e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67181.1 - 4.3e-33 114.4 0.0 7.2e-33 113.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP67181.1 - 9.7e-08 31.3 0.0 8.4e-07 28.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 KEP67181.1 - 0.018 14.1 0.2 0.034 13.1 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEP67181.1 - 0.053 12.8 0.5 0.097 12.0 0.4 1.4 1 0 0 1 1 1 0 RIO1 family Spt5-NGN PF03439.8 KEP67182.1 - 9.1e-21 73.4 0.1 1.8e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KEP67182.1 - 4.5e-11 42.0 2.1 0.03 14.0 0.0 5.5 4 0 0 4 4 4 4 KOW motif Spt5_N PF11942.3 KEP67182.1 - 2.7e-08 34.3 14.6 2.7e-08 34.3 10.2 3.4 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal GCC2_GCC3 PF07699.8 KEP67185.1 - 0.00012 21.5 218.8 0.0012 18.3 3.6 21.2 10 5 8 19 19 19 12 GCC2 and GCC3 Peptidase_M3_N PF08439.5 KEP67185.1 - 0.21 11.6 3.2 1.5 8.8 0.5 2.6 1 1 1 2 2 2 0 Oligopeptidase F OppC_N PF12911.2 KEP67185.1 - 0.6 9.5 0.3 1 8.7 0.2 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Baculo_PEP_C PF04513.7 KEP67185.1 - 2.5 7.9 2.3 19 5.0 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mss4 PF04421.8 KEP67186.1 - 0.071 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Mss4 protein DUF3820 PF12843.2 KEP67186.1 - 0.2 11.2 0.0 0.5 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) RFC1 PF08519.7 KEP67187.1 - 1.8e-35 121.9 0.1 4.3e-35 120.7 0.0 1.7 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 KEP67187.1 - 7.7e-10 39.0 0.0 1.9e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 KEP67187.1 - 1.9e-09 37.4 0.0 4.8e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 KEP67187.1 - 1.1e-06 27.5 0.0 0.065 11.9 0.0 3.0 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 KEP67187.1 - 1.9e-06 27.4 0.0 3.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 KEP67187.1 - 1.5e-05 25.1 0.0 0.00057 20.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEP67187.1 - 0.00011 23.0 0.0 0.00011 23.0 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KEP67187.1 - 0.0015 18.2 0.1 0.005 16.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KEP67187.1 - 0.0019 17.9 0.0 0.0052 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KEP67187.1 - 0.0022 18.2 0.0 0.01 16.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEP67187.1 - 0.006 16.5 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KEP67187.1 - 0.026 13.5 0.0 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Sugar_tr PF00083.19 KEP67189.1 - 2.1e-24 85.9 38.1 1.6e-21 76.4 26.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEP67189.1 - 4.3e-14 51.9 44.9 7.8e-11 41.2 12.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.3 KEP67189.1 - 0.046 13.7 1.5 7.8 6.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) DUF3353 PF11833.3 KEP67190.1 - 4 6.8 4.5 31 3.9 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) NT-C2 PF10358.4 KEP67191.1 - 0.14 11.6 0.2 0.27 10.7 0.2 1.5 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Coatomer_WDAD PF04053.9 KEP67192.1 - 5.1e-125 417.7 0.0 6.8e-125 417.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KEP67192.1 - 2.5e-37 125.4 18.1 2.5e-11 43.0 0.1 9.1 10 0 0 10 10 10 6 WD domain, G-beta repeat PNP_UDP_1 PF01048.15 KEP67194.1 - 1.2e-26 93.1 0.0 2.1e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.20 KEP67198.1 - 3.8e-45 154.0 0.0 3.1e-31 108.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67198.1 - 1.5e-18 66.8 0.0 5.5e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase YcbB PF08664.5 KEP67198.1 - 0.57 9.9 2.4 10 5.9 0.1 2.4 2 0 0 2 2 2 0 YcbB domain Kinase-like PF14531.1 KEP67199.1 - 6.9e-06 25.2 0.0 2.7e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP67199.1 - 1.1e-05 24.7 0.0 9.3e-05 21.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEP67199.1 - 0.0023 17.6 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KEP67199.1 - 0.057 12.4 0.0 0.14 11.2 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 KEP67199.1 - 0.11 11.7 0.0 0.77 9.0 0.0 2.0 2 0 0 2 2 2 0 RIO1 family SAG PF04092.8 KEP67201.1 - 1e-37 129.2 30.7 4e-26 91.8 5.5 2.3 2 0 0 2 2 2 2 SRS domain zf-HC5HC2H_2 PF13832.1 KEP67202.1 - 1.5e-56 189.0 34.3 1e-27 96.2 3.2 5.2 4 0 0 4 4 4 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEP67202.1 - 7.8e-23 80.4 52.5 1.2e-10 41.3 1.6 5.9 7 0 0 7 7 7 3 PHD-like zinc-binding domain PHD_2 PF13831.1 KEP67202.1 - 8.5e-23 79.3 28.8 2.4e-13 49.1 3.1 5.9 6 0 0 6 6 6 3 PHD-finger PHD PF00628.24 KEP67202.1 - 0.00016 21.3 32.6 0.00024 20.7 9.8 8.1 8 0 0 8 8 8 5 PHD-finger Actin PF00022.14 KEP67203.1 - 4.3e-32 111.0 0.0 5.7e-31 107.3 0.0 2.2 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEP67203.1 - 0.015 13.9 0.0 0.28 9.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Not3 PF04065.10 KEP67204.1 - 5e-18 65.2 0.1 3.4e-14 52.6 0.0 3.2 2 1 0 2 2 2 2 Not1 N-terminal domain, CCR4-Not complex component SH3_2 PF07653.12 KEP67204.1 - 0.00019 20.8 0.6 0.00058 19.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KEP67204.1 - 0.00058 19.1 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEP67204.1 - 0.0018 17.7 0.2 0.018 14.6 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain WD40 PF00400.27 KEP67205.1 - 8.7e-07 28.5 0.1 0.9 9.5 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1767 PF08585.7 KEP67206.1 - 0.00016 21.8 0.0 0.00035 20.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) ODAM PF15424.1 KEP67206.1 - 0.043 13.3 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family IMS PF00817.15 KEP67207.1 - 1.7e-25 89.5 0.0 1.7e-24 86.2 0.0 2.6 1 1 0 1 1 1 1 impB/mucB/samB family DUF3505 PF12013.3 KEP67207.1 - 0.035 14.3 0.8 0.081 13.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) SCP2 PF02036.12 KEP67208.1 - 3e-35 120.5 0.5 3.9e-16 59.1 0.0 2.5 2 0 0 2 2 2 2 SCP-2 sterol transfer family adh_short PF00106.20 KEP67208.1 - 3.8e-31 108.2 6.5 7.4e-31 107.3 4.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEP67208.1 - 2.2e-19 69.8 2.8 3.7e-19 69.0 2.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEP67208.1 - 6.4e-11 42.4 0.5 1.4e-10 41.3 0.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Alkyl_sulf_C PF14864.1 KEP67208.1 - 5.4e-09 36.0 0.0 0.00053 19.9 0.0 2.5 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal DUF4070 PF13282.1 KEP67209.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) Ribosomal_L29e PF01779.12 KEP67210.1 - 1.7e-24 85.3 15.4 2.5e-24 84.8 10.7 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Gemini_AL2 PF01440.11 KEP67210.1 - 0.16 12.0 4.1 0.17 11.9 2.8 1.0 1 0 0 1 1 1 0 Geminivirus AL2 protein Mg_trans_NIPA PF05653.9 KEP67211.1 - 1.7e-16 60.0 11.2 1.7e-16 60.0 7.8 1.5 1 1 1 2 2 2 1 Magnesium transporter NIPA EamA PF00892.15 KEP67211.1 - 1.6e-05 24.9 2.3 1.6e-05 24.9 1.6 4.0 3 1 2 5 5 5 1 EamA-like transporter family PMT PF02366.13 KEP67212.1 - 0.026 13.8 1.0 0.035 13.4 0.7 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3815 PF12821.2 KEP67212.1 - 0.059 13.2 1.9 0.17 11.8 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3815) DUF1212 PF06738.7 KEP67212.1 - 0.071 12.5 3.6 0.098 12.1 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF3270 PF11674.3 KEP67212.1 - 0.46 10.5 3.8 0.7 9.9 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) RRM_1 PF00076.17 KEP67213.1 - 3.3e-28 97.1 0.0 1.8e-15 56.3 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67213.1 - 2.7e-21 75.2 0.0 3.2e-10 39.8 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67213.1 - 8.7e-15 54.3 0.1 0.0004 20.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 KEP67214.1 - 5e-28 97.2 3.9 1.5e-20 73.3 0.8 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEP67214.1 - 2e-23 82.2 2.7 1.1e-15 57.6 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) ACBP PF00887.14 KEP67214.1 - 4.1e-22 77.6 0.0 7.2e-22 76.8 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.25 KEP67214.1 - 6.3e-21 73.0 6.6 2.3e-12 46.0 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KEP67214.1 - 2.3e-20 72.1 1.3 1.4e-12 47.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEP67214.1 - 1e-15 56.2 0.1 4.4e-08 32.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat DUF4336 PF14234.1 KEP67214.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Shigella_OspC PF06128.6 KEP67214.1 - 0.017 14.5 0.1 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 Shigella flexneri OspC protein tRNA-synt_2d PF01409.15 KEP67216.1 - 5.4e-87 291.0 0.0 7.5e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KEP67216.1 - 0.00012 21.7 0.1 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 KEP67216.1 - 0.00036 19.4 1.0 0.00075 18.3 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) TYW3 PF02676.9 KEP67217.1 - 4.1e-46 156.6 0.1 2.4e-45 154.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.11 KEP67217.1 - 1.8e-20 73.3 0.0 3.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.1 KEP67217.1 - 3.9e-15 55.3 1.1 0.013 15.2 0.0 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 KEP67217.1 - 3e-14 52.7 13.9 0.013 15.6 0.1 6.7 6 0 0 6 6 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEP67217.1 - 6.2e-14 51.4 0.1 0.036 14.2 0.0 5.1 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 KEP67217.1 - 9.4e-11 41.0 0.1 0.086 12.3 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 KEP67217.1 - 1.8e-10 40.5 0.1 0.0067 16.3 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Methyltransf_26 PF13659.1 KEP67217.1 - 0.00016 21.6 0.1 0.00045 20.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEP67217.1 - 0.007 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Kelch_2 PF07646.10 KEP67217.1 - 0.068 12.9 5.3 7.2 6.5 0.0 4.9 6 0 0 6 6 6 0 Kelch motif DNA_methylase PF00145.12 KEP67217.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_31 PF13847.1 KEP67217.1 - 0.28 10.7 0.0 0.83 9.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain zf-RING_2 PF13639.1 KEP67218.1 - 0.00024 20.8 10.8 0.00053 19.7 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEP67218.1 - 0.00052 19.6 10.9 0.0011 18.5 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP67218.1 - 0.0013 18.3 9.3 0.0027 17.3 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP67218.1 - 0.005 16.9 7.0 0.01 15.9 4.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEP67218.1 - 0.0084 15.8 10.3 0.019 14.6 7.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEP67218.1 - 0.024 14.4 4.5 0.047 13.5 3.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KEP67218.1 - 0.056 13.4 11.1 0.13 12.3 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KEP67218.1 - 1.2 8.9 10.5 7.5 6.3 3.4 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 KEP67218.1 - 2.4 8.1 7.5 16 5.5 5.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain CAF-1_p150 PF11600.3 KEP67219.1 - 7.4e-05 22.2 13.0 7.4e-05 22.2 9.0 1.9 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ARGLU PF15346.1 KEP67219.1 - 0.0089 15.8 30.9 0.0089 15.8 21.4 1.6 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 SPR1 PF15356.1 KEP67219.1 - 0.22 11.8 2.5 0.21 11.9 0.2 2.1 2 1 1 3 3 3 0 Psoriasis susceptibility locus 2 Caldesmon PF02029.10 KEP67219.1 - 0.31 9.4 23.1 0.48 8.7 16.0 1.2 1 0 0 1 1 1 0 Caldesmon U79_P34 PF03064.11 KEP67219.1 - 0.63 9.5 11.0 1.3 8.4 7.6 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.3 KEP67219.1 - 1 8.0 13.5 1.8 7.2 9.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 KEP67219.1 - 2.1 7.7 20.7 3.7 6.9 14.3 1.3 1 0 0 1 1 1 0 DDRGK domain Iron_permease PF04120.7 KEP67219.1 - 4.3 6.9 6.4 12 5.5 4.4 1.7 1 0 0 1 1 1 0 Low affinity iron permease Mnd1 PF03962.10 KEP67219.1 - 10 5.7 15.6 78 2.8 9.3 2.2 2 0 0 2 2 2 0 Mnd1 family zf-RanBP PF00641.13 KEP67220.1 - 0.00012 21.0 3.6 0.00012 21.0 2.5 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-tcix PF14952.1 KEP67220.1 - 0.034 13.4 6.0 0.075 12.3 4.2 1.6 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF35_N PF12172.3 KEP67220.1 - 0.094 12.6 6.1 0.05 13.5 1.6 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ribosomal_S8 PF00410.14 KEP67222.1 - 3.8e-24 84.9 0.0 4.9e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 MRFAP1 PF15155.1 KEP67222.1 - 0.019 15.2 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 MORF4 family-associated protein1 Aminotran_1_2 PF00155.16 KEP67223.1 - 2.5e-27 95.7 0.0 3.1e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KEP67223.1 - 1.6e-06 26.9 0.0 3.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase Med29 PF11568.3 KEP67224.1 - 0.17 11.9 0.0 0.83 9.6 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 29 DUF3523 PF12037.3 KEP67226.1 - 6.6e-94 313.9 28.2 1e-93 313.3 19.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.24 KEP67226.1 - 9.8e-24 84.0 0.1 4.5e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEP67226.1 - 4.7e-05 22.5 2.1 4.8e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus FtsK_SpoIIIE PF01580.13 KEP67226.1 - 0.00017 21.1 3.4 0.0071 15.8 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KEP67226.1 - 0.00048 20.2 8.0 0.0062 16.6 0.0 3.8 2 2 2 4 4 3 1 AAA domain AAA_17 PF13207.1 KEP67226.1 - 0.0013 19.5 0.1 0.0013 19.5 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEP67226.1 - 0.0018 18.2 0.0 0.0018 18.2 0.0 3.9 2 2 0 3 3 2 1 AAA ATPase domain Zot PF05707.7 KEP67226.1 - 0.0048 16.3 0.1 0.28 10.6 0.0 2.8 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_14 PF13173.1 KEP67226.1 - 0.007 16.2 0.0 0.038 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEP67226.1 - 0.0087 15.9 0.0 0.0087 15.9 0.0 3.2 2 2 1 3 3 1 1 AAA domain Mg_chelatase PF01078.16 KEP67226.1 - 0.0093 15.1 0.1 0.055 12.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEP67226.1 - 0.012 15.2 1.7 0.029 14.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEP67226.1 - 0.017 14.7 0.0 0.043 13.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KEP67226.1 - 0.038 13.5 0.0 0.038 13.5 0.0 2.2 2 1 1 3 3 2 0 AAA domain RNA_helicase PF00910.17 KEP67226.1 - 0.076 13.1 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KEP67226.1 - 0.49 10.0 0.0 0.49 10.0 0.0 3.5 4 1 0 4 4 4 0 NACHT domain AAA_25 PF13481.1 KEP67226.1 - 0.77 9.1 7.6 0.57 9.5 0.1 3.3 2 2 1 3 3 2 0 AAA domain Med15 PF09606.5 KEP67226.1 - 3.4 5.7 19.8 4.5 5.3 13.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MS_channel PF00924.13 KEP67227.1 - 4.6e-13 48.9 1.9 8.4e-13 48.1 1.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel C2-set PF05790.10 KEP67227.1 - 0.36 10.8 1.0 1.7 8.7 0.3 2.2 2 0 0 2 2 2 0 Immunoglobulin C2-set domain EI24 PF07264.6 KEP67228.1 - 5.4e-17 61.9 26.8 1.8e-05 24.3 0.1 4.3 3 1 0 3 3 3 3 Etoposide-induced protein 2.4 (EI24) SAG PF04092.8 KEP67232.1 - 1.4e-11 44.8 0.1 2e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 SRS domain Topoisom_I PF01028.15 KEP67233.1 - 1.3e-93 312.4 5.7 2.3e-93 311.6 3.9 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 KEP67233.1 - 8.9e-83 276.8 3.4 1.3e-82 276.2 0.1 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 KEP67233.1 - 5.8e-32 109.1 0.2 1.4e-31 107.9 0.2 1.7 1 0 0 1 1 1 1 C-terminal topoisomerase domain Abhydrolase_6 PF12697.2 KEP67235.1 - 4.9e-29 101.8 0.0 6.8e-28 98.1 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEP67235.1 - 2.7e-10 40.1 0.3 1.6e-09 37.6 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP67235.1 - 9.8e-10 38.3 0.0 4.9e-06 26.2 0.0 3.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF676 PF05057.9 KEP67235.1 - 0.01 15.1 0.0 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 KEP67235.1 - 0.017 15.3 0.0 0.084 13.0 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.8 KEP67235.1 - 0.02 14.4 0.0 0.07 12.7 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein Esterase PF00756.15 KEP67235.1 - 0.022 14.1 0.1 0.052 12.9 0.1 1.6 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 KEP67235.1 - 0.053 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEP67235.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PAZ_siRNAbind PF12212.3 KEP67235.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain Lipase_3 PF01764.20 KEP67235.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 KEP67235.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PP28 PF10252.4 KEP67236.1 - 2.7e-20 72.1 15.5 2.7e-20 72.1 10.8 2.3 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 HlyD PF00529.15 KEP67236.1 - 4 6.6 11.5 6.8 5.8 8.0 1.3 1 1 0 1 1 1 0 HlyD family secretion protein A_deaminase PF00962.17 KEP67238.1 - 1.5e-90 303.5 0.0 2.4e-90 302.7 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase SHMT PF00464.14 KEP67244.1 - 4.7e-176 585.0 0.0 5.6e-176 584.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase CoA_transf_3 PF02515.12 KEP67244.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 CoA-transferase family III Resistin PF06954.6 KEP67248.1 - 2.2 8.5 8.6 3 8.1 6.0 1.3 1 1 0 1 1 1 0 Resistin DUF4201 PF13870.1 KEP67249.1 - 0.0036 16.7 31.1 0.089 12.2 7.7 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) MscS_porin PF12795.2 KEP67249.1 - 0.0089 15.3 11.8 0.0089 15.3 8.2 2.9 2 1 1 3 3 3 1 Mechanosensitive ion channel porin domain Spc7 PF08317.6 KEP67249.1 - 0.022 13.4 23.4 0.06 11.9 6.1 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 KEP67249.1 - 0.032 13.8 39.9 0.2 11.2 10.6 3.2 2 1 0 2 2 2 0 IncA protein BLOC1_2 PF10046.4 KEP67249.1 - 0.04 14.0 0.4 0.04 14.0 0.3 3.5 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LemA PF04011.7 KEP67249.1 - 0.24 10.4 7.9 0.17 10.9 2.2 2.4 2 0 0 2 2 2 0 LemA family ATG16 PF08614.6 KEP67249.1 - 0.26 11.1 37.2 2.1 8.1 7.2 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 KEP67249.1 - 1 8.3 35.6 0.15 11.1 2.4 2.9 2 1 1 3 3 3 0 Autophagy protein Apg6 L31 PF09784.4 KEP67249.1 - 1.4 8.9 6.9 2.8 8.0 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 GAS PF13851.1 KEP67249.1 - 1.5 7.9 33.3 1.7 7.8 8.1 3.3 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 KEP67249.1 - 1.7 8.5 7.1 3.4 7.6 1.4 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 KEP67249.1 - 3.5 7.9 6.4 11 6.2 0.1 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0184 PF03670.8 KEP67249.1 - 4.8 7.4 10.1 0.88 9.7 1.4 3.5 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) DUF342 PF03961.8 KEP67249.1 - 7.4 4.8 22.1 0.094 11.1 3.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF342) Ribosomal_L18p PF00861.17 KEP67250.1 - 6.8e-22 77.9 1.4 2e-21 76.3 1.0 1.7 1 1 0 1 1 1 1 Ribosomal L18p/L5e family RAP PF08373.5 KEP67252.1 - 1.2e-07 31.4 0.0 2e-06 27.4 0.0 2.5 1 1 0 1 1 1 1 RAP domain L27_1 PF09058.5 KEP67252.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 L27_1 Mycoplasma_p37 PF06646.6 KEP67252.1 - 9.7 5.1 0.0 16 4.4 0.0 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 Kinesin PF00225.18 KEP67254.1 - 2.4e-88 296.0 0.0 3.4e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Cyclin_N PF00134.18 KEP67255.1 - 0.011 15.2 0.0 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF3150 PF11348.3 KEP67257.1 - 0.037 13.1 0.1 0.054 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Tmemb_cc2 PF10267.4 KEP67257.1 - 0.074 11.6 1.0 0.13 10.8 0.7 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Phostensin_N PF13916.1 KEP67257.1 - 0.077 12.9 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal OmpH PF03938.9 KEP67257.1 - 0.33 10.8 2.9 0.3 11.0 1.3 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) EphA2_TM PF14575.1 KEP67258.1 - 0.027 14.8 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CoA_binding_3 PF13727.1 KEP67258.1 - 0.057 13.2 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 CoA-binding domain Protocadherin PF08374.6 KEP67258.1 - 0.64 9.6 2.4 1.4 8.4 1.7 1.4 1 1 0 1 1 1 0 Protocadherin Trichoplein PF13868.1 KEP67261.1 - 2.6e-63 213.5 147.1 2.6e-63 213.5 102.0 2.1 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin ThiF PF00899.16 KEP67263.1 - 1.7e-37 128.2 0.0 2.8e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KEP67263.1 - 2.7e-20 71.7 0.3 7.8e-20 70.2 0.1 1.9 2 0 0 2 2 2 1 MoeZ/MoeB domain Baculo_44 PF04631.7 KEP67263.1 - 0.18 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus hypothetical protein Cupin_8 PF13621.1 KEP67264.1 - 6.9e-31 107.6 0.0 7.5e-30 104.2 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KEP67264.1 - 3.9e-07 29.6 0.0 0.0032 16.7 0.0 2.6 2 0 0 2 2 2 2 Cupin superfamily protein DUF3336 PF11815.3 KEP67265.1 - 1.3e-28 99.3 0.8 2.4e-28 98.4 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KEP67265.1 - 1.7e-20 73.8 0.0 3.8e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Methyltransf_26 PF13659.1 KEP67266.1 - 0.0024 17.8 0.2 0.0074 16.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KEP67266.1 - 0.0069 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 KEP67266.1 - 0.029 13.3 0.0 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase COG4 PF08318.7 KEP67268.1 - 1e-08 34.3 0.0 3.5e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 COG4 transport protein Sec6 PF06046.8 KEP67268.1 - 0.012 13.7 2.5 4.9 5.1 0.0 3.5 4 0 0 4 4 4 0 Exocyst complex component Sec6 DUF3138 PF11336.3 KEP67268.1 - 9.8 4.2 7.5 1.8 6.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) GIY-YIG PF01541.19 KEP67270.1 - 8.1e-08 32.5 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain C1_1 PF00130.17 KEP67270.1 - 0.65 9.7 5.0 0.89 9.3 2.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRM_1 PF00076.17 KEP67272.1 - 1.2e-17 63.3 0.0 2.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67272.1 - 2.7e-13 49.6 0.0 6.9e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67272.1 - 1.7e-07 31.0 0.0 4.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mg_trans_NIPA PF05653.9 KEP67273.1 - 1.3e-23 83.3 17.0 3.1e-12 46.0 1.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KEP67273.1 - 0.00089 19.4 9.6 0.00089 19.4 6.7 3.5 2 1 2 4 4 4 2 Multidrug resistance efflux transporter EamA PF00892.15 KEP67273.1 - 0.019 15.0 9.2 0.019 15.0 6.3 3.9 3 2 1 4 4 4 0 EamA-like transporter family Phasin PF05597.6 KEP67274.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tubulin PF00091.20 KEP67276.1 - 1.4e-70 237.4 0.0 2.3e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEP67276.1 - 2.1e-49 166.7 0.2 3.1e-49 166.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEP67276.1 - 0.0001 22.3 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KEP67276.1 - 0.0067 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain MKT1_C PF12246.3 KEP67277.1 - 2.4e-37 128.2 0.0 3.9e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KEP67277.1 - 2.5e-18 66.1 0.0 6e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KEP67277.1 - 1.1e-12 47.8 0.0 2.1e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KEP67277.1 - 5.8e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain DUF3606 PF12244.3 KEP67277.1 - 0.24 11.0 0.2 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Auto_anti-p27 PF06677.7 KEP67278.1 - 6.2e-13 48.2 1.5 1.2e-12 47.3 1.0 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Phage_P2_GpE PF06528.7 KEP67278.1 - 0.084 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Phage P2 GpE Ribosomal_S19e PF01090.14 KEP67281.1 - 7.4e-54 180.9 0.0 9.1e-54 180.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.5 KEP67281.1 - 0.02 14.5 0.0 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF1664 PF07889.7 KEP67282.1 - 0.31 10.8 7.5 0.64 9.8 3.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATP-synt_C PF00137.16 KEP67283.1 - 1.6e-30 104.7 31.8 3.8e-17 61.9 8.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Tachykinin PF02202.11 KEP67283.1 - 0.55 10.0 4.0 6.5 6.7 0.4 3.3 2 0 0 2 2 2 0 Tachykinin family Hexose_dehydrat PF03559.9 KEP67285.1 - 0.0042 16.1 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 NDP-hexose 2,3-dehydratase WD40 PF00400.27 KEP67286.1 - 1.1e-06 28.3 9.2 7.3e-05 22.4 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Sec63 PF02889.11 KEP67288.1 - 1.2e-184 612.7 0.0 2.7e-103 345.4 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KEP67288.1 - 2.1e-43 147.7 0.7 8.6e-29 100.1 0.1 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP67288.1 - 6.7e-11 41.9 0.0 2.6e-08 33.5 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEP67288.1 - 1.7e-09 37.7 0.1 5.7e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEP67288.1 - 0.0014 18.8 1.8 0.13 12.4 0.1 3.5 4 1 0 4 4 4 1 AAA domain Peptidase_M91 PF14891.1 KEP67288.1 - 0.03 14.3 0.2 0.072 13.1 0.2 1.5 1 0 0 1 1 1 0 Effector protein AAA PF00004.24 KEP67288.1 - 0.067 13.3 0.0 0.28 11.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PBP1_TM PF14812.1 KEP67289.1 - 0.099 12.9 2.7 0.17 12.2 1.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.11 KEP67289.1 - 0.12 11.3 0.5 0.14 11.1 0.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Defensin_propep PF00879.13 KEP67289.1 - 1.8 8.5 3.7 3.3 7.7 2.5 1.6 1 1 0 1 1 1 0 Defensin propeptide IF4E PF01652.13 KEP67290.1 - 1.9e-39 134.8 0.1 2.4e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DnaJ PF00226.26 KEP67291.1 - 5.1e-12 45.3 0.0 2.2e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain YL1_C PF08265.6 KEP67292.1 - 0.017 14.6 0.3 0.4 10.2 0.0 2.9 3 0 0 3 3 3 0 YL1 nuclear protein C-terminal domain F5_F8_type_C PF00754.20 KEP67292.1 - 0.024 14.4 0.1 0.024 14.4 0.0 2.1 2 0 0 2 2 2 0 F5/8 type C domain DEAD PF00270.24 KEP67293.1 - 3.5e-22 78.6 0.0 1.5e-21 76.5 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP67293.1 - 1.1e-13 50.8 0.0 7.3e-13 48.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UCH PF00443.24 KEP67294.1 - 4.4e-45 153.8 0.0 6.9e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP67294.1 - 7.4e-14 51.8 0.0 1.6e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Notch PF00066.12 KEP67295.1 - 2.1e-07 31.0 12.0 7.6e-07 29.2 8.3 2.0 1 0 0 1 1 1 1 LNR domain DUF4436 PF14494.1 KEP67295.1 - 0.35 10.1 0.1 0.59 9.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) TSP_1 PF00090.14 KEP67296.1 - 1.8e-104 341.7 231.2 2.3e-11 43.5 1.4 21.9 20 2 0 20 20 20 16 Thrombospondin type 1 domain Notch PF00066.12 KEP67296.1 - 3.7e-16 59.0 64.9 1.9e-09 37.6 10.6 9.1 7 0 0 7 7 7 3 LNR domain SAM_adeno_trans PF01887.11 KEP67296.1 - 3.8 6.4 0.0 6.7 5.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Abhydrolase_5 PF12695.2 KEP67300.1 - 7.6e-23 80.8 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP67300.1 - 1.7e-11 44.4 0.9 8.4e-10 38.9 0.2 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEP67300.1 - 4.1e-05 23.2 0.6 0.0012 18.4 0.1 2.3 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KEP67300.1 - 0.00077 18.9 0.0 0.022 14.1 0.0 2.6 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF818 PF05677.7 KEP67300.1 - 0.0012 17.7 0.1 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.16 KEP67300.1 - 0.0018 17.5 0.0 0.016 14.4 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KEP67300.1 - 0.038 13.8 0.1 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase PucR PF07905.6 KEP67300.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family 4F5 PF04419.9 KEP67300.1 - 8.9 7.1 10.5 1.3 9.8 4.1 2.0 2 0 0 2 2 2 0 4F5 protein family EF-hand_7 PF13499.1 KEP67301.1 - 2.8e-12 46.5 0.7 1.7e-07 31.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEP67301.1 - 3.6e-11 41.5 0.7 3.5e-05 22.8 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEP67301.1 - 4.1e-11 41.7 0.3 1.8e-05 24.2 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 KEP67301.1 - 1e-07 30.9 4.1 4.6e-05 22.5 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KEP67301.1 - 1.2e-06 27.9 0.4 0.0042 16.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair YniB PF14002.1 KEP67301.1 - 0.01 15.3 1.4 0.038 13.4 0.1 2.4 3 0 0 3 3 3 0 YniB-like protein Mlo PF03094.10 KEP67301.1 - 0.018 13.1 12.9 0.04 12.0 2.0 3.8 3 1 0 3 3 3 0 Mlo family DUF2393 PF09624.5 KEP67301.1 - 1 8.9 4.7 10 5.6 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) DUF1469 PF07332.6 KEP67301.1 - 4.3 7.0 11.9 2.1 8.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) MOZART1 PF12554.3 KEP67302.1 - 3.9e-22 77.4 0.6 4.9e-22 77.1 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 KEP67302.1 - 0.06 12.9 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated IBN_N PF03810.14 KEP67303.1 - 2e-11 43.6 0.0 1.5e-10 40.8 0.0 2.7 1 1 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.5 KEP67303.1 - 6.4e-08 31.5 0.3 1.1e-06 27.5 0.0 2.8 3 1 0 3 3 3 1 Cse1 Sporozoite_P67 PF05642.6 KEP67303.1 - 0.89 7.3 3.2 1.8 6.3 2.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.5 KEP67303.1 - 1.7 7.6 7.7 3 6.8 5.3 1.3 1 0 0 1 1 1 0 BUD22 NUFIP1 PF10453.4 KEP67306.1 - 8.2e-07 28.4 0.0 1.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.3 KEP67306.1 - 0.0053 16.8 0.5 0.0098 16.0 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Med4 PF10018.4 KEP67307.1 - 0.02 14.3 0.0 0.02 14.3 0.0 2.6 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Proteasome PF00227.21 KEP67308.1 - 3.3e-45 153.7 2.4 4.1e-45 153.3 1.7 1.1 1 0 0 1 1 1 1 Proteasome subunit V-SNARE_C PF12352.3 KEP67312.1 - 3.1e-10 39.9 1.6 3.1e-10 39.9 1.1 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEP67312.1 - 6.1e-06 25.8 0.1 1.3e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Sec20 Eapp_C PF10238.4 KEP67313.1 - 4.1e-33 114.1 1.0 4.1e-33 114.1 0.7 2.7 2 2 0 2 2 2 1 E2F-associated phosphoprotein amfpi-1 PF12190.3 KEP67313.1 - 0.19 12.2 0.1 0.19 12.2 0.1 3.0 2 1 0 2 2 2 0 Fungal protease inhibitor RabGAP-TBC PF00566.13 KEP67314.1 - 7.8e-09 35.3 4.8 0.03 13.8 0.3 3.8 4 0 0 4 4 4 3 Rab-GTPase-TBC domain Ribosomal_L4 PF00573.17 KEP67316.1 - 2.2e-43 147.8 0.0 3.1e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family zf-LYAR PF08790.6 KEP67317.1 - 5.1e-11 42.0 9.2 1e-09 37.8 3.0 2.3 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger Clathrin_lg_ch PF01086.12 KEP67317.1 - 0.0007 19.5 2.7 0.00084 19.3 1.9 1.1 1 0 0 1 1 1 1 Clathrin light chain DUF2201_N PF13203.1 KEP67317.1 - 0.0065 15.6 4.2 0.0091 15.2 2.9 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain zf-TRAF PF02176.13 KEP67317.1 - 0.015 15.6 5.6 0.25 11.7 1.5 2.6 1 1 1 2 2 2 0 TRAF-type zinc finger SUI1 PF01253.17 KEP67317.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Translation initiation factor SUI1 IBR PF01485.16 KEP67317.1 - 1.6 8.6 9.2 0.7 9.8 4.4 2.0 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 KEP67317.1 - 2.2 8.3 6.4 8 6.5 4.4 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain LIM PF00412.17 KEP67317.1 - 2.5 8.2 9.7 14 5.8 5.3 2.7 1 1 1 2 2 2 0 LIM domain GF_recep_IV PF14843.1 KEP67317.1 - 2.7 7.6 11.2 3.5 7.2 6.7 1.9 2 1 1 3 3 3 0 Growth factor receptor domain IV zf-DNL PF05180.7 KEP67317.1 - 3.4 7.4 10.4 24 4.7 5.9 2.8 2 1 0 2 2 2 0 DNL zinc finger Inositol_P PF00459.20 KEP67318.1 - 3.6e-41 141.2 0.0 4.6e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 KEP67318.1 - 0.088 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase ubiquitin PF00240.18 KEP67319.1 - 6.3e-21 73.5 0.1 1.1e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KEP67319.1 - 1.5e-08 34.2 0.9 4.3e-08 32.7 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 KEP67319.1 - 3.1e-07 29.9 0.1 5.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 KEP67319.1 - 0.002 17.5 0.3 0.0084 15.5 0.0 2.3 2 0 0 2 2 2 1 CUE domain Ubiquitin_2 PF14560.1 KEP67319.1 - 0.0069 16.6 0.1 0.017 15.3 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.5 KEP67319.1 - 0.018 15.5 0.0 0.047 14.2 0.0 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.1 KEP67319.1 - 0.099 12.5 0.1 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Med15 PF09606.5 KEP67319.1 - 9 4.3 42.6 11 4.0 29.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glyco_hydro_46 PF01374.13 KEP67320.1 - 0.11 12.0 2.1 0.15 11.5 1.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 RNA_pol_3_Rpc31 PF11705.3 KEP67321.1 - 4e-11 43.3 8.6 6.8e-11 42.5 5.9 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.5 KEP67321.1 - 0.043 14.3 5.4 0.078 13.5 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) IFT43 PF15305.1 KEP67321.1 - 0.056 13.4 0.5 0.082 12.9 0.3 1.2 1 0 0 1 1 1 0 Intraflagellar transport protein 43 LCCL PF03815.14 KEP67322.1 - 5.2e-24 84.0 0.8 1.8e-23 82.3 0.2 2.2 2 0 0 2 2 2 1 LCCL domain F5_F8_type_C PF00754.20 KEP67322.1 - 1.7e-14 53.7 0.2 1.1e-10 41.4 0.0 2.4 2 0 0 2 2 2 2 F5/8 type C domain XRCC1_N PF01834.11 KEP67322.1 - 0.0092 15.4 0.6 0.058 12.8 0.1 2.2 2 0 0 2 2 2 1 XRCC1 N terminal domain Fibrinogen_C PF00147.13 KEP67322.1 - 0.017 14.6 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Laminin_G_2 PF02210.19 KEP67322.1 - 0.08 12.9 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Laminin G domain NARP1 PF12569.3 KEP67323.1 - 4.3e-119 398.6 24.0 9.8e-88 295.1 10.7 4.8 4 1 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 KEP67323.1 - 5.7e-13 49.1 12.8 0.019 15.6 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEP67323.1 - 3.6e-12 45.7 10.2 0.00075 19.0 0.0 5.3 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 KEP67323.1 - 2.1e-11 42.8 19.8 6.4e-06 25.6 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEP67323.1 - 6.5e-09 35.6 11.9 0.63 10.8 0.0 9.1 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEP67323.1 - 4.8e-07 29.0 1.8 0.0074 16.0 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEP67323.1 - 9.9e-06 25.3 3.3 2.8 8.3 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEP67323.1 - 3.6e-05 23.5 18.2 0.046 13.6 0.1 6.4 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEP67323.1 - 5.7e-05 22.5 5.5 0.0084 15.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEP67323.1 - 0.00018 21.0 1.3 0.37 10.6 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP67323.1 - 0.033 14.5 14.6 2.3 8.6 0.0 6.9 6 2 2 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP67323.1 - 0.42 11.1 5.9 11 6.7 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat HemY_N PF07219.8 KEP67323.1 - 2.9 7.4 5.6 1.1 8.8 0.9 2.5 3 0 0 3 3 3 0 HemY protein N-terminus DUF1289 PF06945.8 KEP67325.1 - 3 7.3 9.7 2.3 7.7 1.2 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) HlyD_2 PF12700.2 KEP67328.1 - 0.0049 16.0 0.2 0.0049 16.0 0.1 2.2 2 1 0 2 2 2 1 HlyD family secretion protein Arm PF00514.18 KEP67328.1 - 0.032 14.0 3.0 2.1 8.2 0.0 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat FANCI_S2 PF14676.1 KEP67328.1 - 0.058 13.2 0.4 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 FANCI solenoid 2 Folate_rec PF03024.9 KEP67330.1 - 1.9e-15 56.8 7.2 1.9e-15 56.8 5.0 2.2 2 1 0 2 2 2 1 Folate receptor family Mg_trans_NIPA PF05653.9 KEP67331.1 - 2.5e-06 26.6 4.0 0.00025 20.1 0.5 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KEP67331.1 - 0.0053 16.9 20.6 0.02 15.0 4.9 3.2 2 1 0 2 2 2 2 Multidrug resistance efflux transporter Fasciclin PF02469.17 KEP67333.1 - 2.7e-09 37.0 0.0 5.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain Citrate_synt PF00285.16 KEP67334.1 - 9.6e-22 77.1 0.0 4.7e-20 71.6 0.0 2.7 1 1 1 2 2 2 1 Citrate synthase Ligase_CoA PF00549.14 KEP67334.1 - 4e-10 39.4 0.0 1.3e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.14 KEP67334.1 - 6.2e-09 36.2 0.0 1.4e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 KEP67334.1 - 6e-07 29.0 0.0 0.00023 20.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Hep_59 PF07052.6 KEP67334.1 - 0.19 12.1 0.1 0.4 11.0 0.1 1.4 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 RRM_1 PF00076.17 KEP67335.1 - 1e-13 50.7 0.0 2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67335.1 - 2.1e-11 43.6 0.0 4.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67335.1 - 4.1e-07 29.7 0.0 8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-SAP30 PF13866.1 KEP67335.1 - 2.1 8.0 7.0 3.5 7.3 0.4 2.7 2 0 0 2 2 2 0 SAP30 zinc-finger zf-RING_UBOX PF13445.1 KEP67337.1 - 3.5e-12 45.8 3.0 9.1e-12 44.5 2.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 KEP67337.1 - 1.7e-10 40.7 0.0 3.3e-09 36.5 0.0 2.6 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_5 PF14634.1 KEP67337.1 - 6.3e-06 25.8 4.9 6.3e-06 25.8 3.4 3.0 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP67337.1 - 8.1e-06 25.7 3.4 8.1e-06 25.7 2.4 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Acyltransferase PF01553.16 KEP67339.1 - 2.7e-18 65.6 0.0 4.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF2514 PF10721.4 KEP67340.1 - 0.055 13.1 0.8 0.1 12.3 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Acylphosphatase PF00708.13 KEP67340.1 - 0.066 13.3 0.0 1.5 8.9 0.0 2.6 2 1 1 3 3 3 0 Acylphosphatase Aminotran_5 PF00266.14 KEP67340.1 - 0.084 11.6 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-V RRM_1 PF00076.17 KEP67342.1 - 3.3e-20 71.4 0.1 1.6e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67342.1 - 2.3e-18 65.7 0.1 3.1e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67342.1 - 1.1e-12 47.7 0.1 1.8e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KEP67342.1 - 0.00022 20.8 0.1 0.0091 15.5 0.0 2.2 2 0 0 2 2 2 1 Calcipressin RRM_3 PF08777.6 KEP67342.1 - 0.00054 19.7 0.1 0.79 9.5 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 KEP67342.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 MIP-T3 PF10243.4 KEP67343.1 - 0.17 10.3 59.6 0.21 10.0 41.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tom37_C PF11801.3 KEP67344.1 - 0.18 11.6 1.6 0.52 10.1 1.1 1.7 1 0 0 1 1 1 0 Tom37 C-terminal domain VWA_2 PF13519.1 KEP67345.1 - 3e-08 33.9 0.1 5.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 KEP67345.1 - 0.79 9.4 9.4 6 6.7 0.5 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif GTP_EFTU PF00009.22 KEP67346.1 - 4.1e-57 192.6 0.0 6.5e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KEP67346.1 - 3.4e-41 139.5 0.0 6e-41 138.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 KEP67346.1 - 3.7e-30 103.5 0.0 6.4e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KEP67346.1 - 2.1e-21 75.5 0.0 7.8e-21 73.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEP67346.1 - 3e-11 43.2 0.1 6.8e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SpoIIE PF07228.7 KEP67347.1 - 1.9e-07 30.9 0.0 6.5e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF2269 PF10027.4 KEP67349.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF3112 PF11309.3 KEP67349.1 - 0.1 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Acetyltransf_11 PF13720.1 KEP67350.1 - 0.021 15.0 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 HTH_AsnC-type PF13404.1 KEP67350.1 - 0.051 13.1 0.1 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain IQ PF00612.22 KEP67352.1 - 3.4e-05 23.1 0.4 0.00012 21.4 0.3 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Flu_B_M2 PF04772.7 KEP67352.1 - 0.14 12.2 0.3 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Influenza B matrix protein 2 (BM2) AP2 PF00847.15 KEP67353.1 - 9.4e-09 35.2 2.4 0.00042 20.4 1.4 2.7 3 0 0 3 3 3 2 AP2 domain ACDC PF14733.1 KEP67353.1 - 6.2e-07 29.4 0.0 2.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 AP2-coincident C-terminal Thioredoxin PF00085.15 KEP67354.1 - 2.5e-41 139.5 0.0 4.4e-24 84.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KEP67354.1 - 8.9e-14 51.7 0.0 9.1e-09 35.3 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KEP67354.1 - 6.4e-08 32.7 0.1 8.7e-05 22.6 0.0 3.9 2 2 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KEP67354.1 - 2.1e-05 24.1 0.0 0.17 11.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.1 KEP67354.1 - 3e-05 24.0 0.0 0.1 12.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KEP67354.1 - 0.00011 22.2 0.0 0.019 14.9 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KEP67354.1 - 0.011 15.2 0.0 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin DUF4463 PF14703.1 KEP67355.1 - 0.19 12.2 1.8 0.42 11.1 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Kazal_1 PF00050.16 KEP67356.1 - 4.2e-19 68.2 10.9 1.4e-08 34.6 2.2 3.4 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 KEP67356.1 - 7.6e-19 67.3 9.7 2.8e-07 30.3 1.4 3.6 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain ECH PF00378.15 KEP67357.1 - 3.9e-21 75.2 0.0 5.3e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KEP67357.1 - 1.8e-20 73.2 0.0 1.8e-13 50.6 0.0 2.5 2 0 0 2 2 2 2 2-enoyl-CoA Hydratase C-terminal region Gal4_dimer PF03902.8 KEP67357.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain Proteasom_Rpn13 PF04683.8 KEP67358.1 - 1.3e-27 95.7 0.0 1.9e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RRM_1 PF00076.17 KEP67359.1 - 0.00022 20.7 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67359.1 - 0.0053 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YfhD PF14151.1 KEP67360.1 - 0.075 13.1 0.8 0.18 11.9 0.6 1.7 1 0 0 1 1 1 0 YfhD-like protein COG6 PF06419.6 KEP67361.1 - 3.4e-28 98.1 0.0 1.7e-09 36.4 0.0 5.6 5 1 1 6 6 6 4 Conserved oligomeric complex COG6 Adap_comp_sub PF00928.16 KEP67362.1 - 9.5e-06 24.8 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family HpaB PF03241.8 KEP67362.1 - 0.54 9.0 0.0 0.93 8.2 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal SAG PF04092.8 KEP67363.1 - 4.1e-07 30.4 0.3 0.0051 17.1 0.0 2.8 2 1 0 2 2 2 2 SRS domain BTB PF00651.26 KEP67364.1 - 1.1e-19 70.4 1.9 0.0028 17.5 0.0 5.5 5 1 1 6 6 6 4 BTB/POZ domain Hydrolase PF00702.21 KEP67365.1 - 4.2e-19 69.8 0.0 6.4e-18 65.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEP67365.1 - 5.6e-17 61.5 0.5 5.6e-17 61.5 0.3 2.7 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KEP67365.1 - 1.1e-12 48.4 0.0 2.9e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEP67365.1 - 3.8e-09 36.3 0.0 9.6e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD_2 PF13419.1 KEP67365.1 - 0.00015 21.9 0.0 0.00039 20.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEP67365.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PseudoU_synth_1 PF01416.15 KEP67366.1 - 3.5e-24 85.2 0.0 2.2e-11 44.0 0.0 3.5 3 0 0 3 3 3 3 tRNA pseudouridine synthase Glutaminase PF04960.10 KEP67366.1 - 0.049 12.6 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutaminase ER_lumen_recept PF00810.13 KEP67367.1 - 2.8e-40 138.2 3.7 2.8e-40 138.2 2.6 2.1 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KEP67367.1 - 0.019 14.5 0.4 0.019 14.5 0.3 3.6 2 1 0 2 2 2 0 PQ loop repeat NT-C2 PF10358.4 KEP67368.1 - 1.4e-06 27.8 0.0 6.8e-05 22.3 0.0 2.7 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Metallophos PF00149.23 KEP67369.1 - 2.9e-37 128.0 0.5 3.7e-37 127.6 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AP2 PF00847.15 KEP67370.1 - 0.00029 20.8 1.3 0.00029 20.8 0.9 2.8 3 0 0 3 3 3 1 AP2 domain CCDC14 PF15254.1 KEP67370.1 - 0.19 10.0 0.0 0.31 9.3 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 IF3_C PF00707.17 KEP67371.1 - 2e-20 72.3 0.1 3.9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain PP2C PF00481.16 KEP67372.1 - 1.4e-55 188.4 0.8 1.9e-55 188.0 0.6 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEP67372.1 - 0.0023 17.3 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C zf-HC5HC2H_2 PF13832.1 KEP67374.1 - 2e-18 66.3 30.6 7.3e-13 48.4 2.5 3.9 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEP67374.1 - 5.8e-14 51.9 34.4 1.5e-09 37.8 4.0 4.6 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.24 KEP67374.1 - 2.1e-05 24.1 20.6 8.8e-05 22.1 7.8 7.7 8 0 0 8 8 8 2 PHD-finger Spot_14 PF07084.7 KEP67374.1 - 2.6 7.9 2.4 6.5 6.6 0.2 2.7 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 Clathrin PF00637.15 KEP67376.1 - 3.3e-07 29.9 0.0 0.0084 15.7 0.0 2.3 2 0 0 2 2 2 2 Region in Clathrin and VPS CPSF_A PF03178.10 KEP67379.1 - 2.6e-21 76.0 0.0 4.8e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region zf-DHHC PF01529.15 KEP67380.1 - 3.7e-38 130.6 10.4 3.7e-38 130.6 7.2 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-DHHC PF01529.15 KEP67381.1 - 4.5e-37 127.0 5.4 6.8e-37 126.5 3.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase PA28_beta PF02252.13 KEP67383.1 - 3.2e-50 169.5 0.7 4.6e-50 169.0 0.5 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Herpes_BLLF1 PF05109.8 KEP67383.1 - 0.22 9.4 8.6 0.39 8.6 6.0 1.3 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RR_TM4-6 PF06459.7 KEP67384.1 - 0.39 10.5 14.0 0.45 10.3 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.7 KEP67384.1 - 1.7 6.9 20.5 1.9 6.7 14.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KEP67384.1 - 5.3 4.8 22.9 6.4 4.5 15.9 1.0 1 0 0 1 1 1 0 Nop14-like family COPI_assoc PF08507.5 KEP67385.1 - 0.033 13.8 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 COPI associated protein FixQ PF05545.6 KEP67385.1 - 3.8 7.2 6.2 1.8 8.2 0.3 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Tad PF13400.1 KEP67385.1 - 5.3 7.1 8.0 0.33 11.0 1.0 1.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like DUF3458 PF11940.3 KEP67386.1 - 2.7e-116 388.4 1.4 3.8e-116 387.9 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 KEP67386.1 - 1.7e-66 224.9 0.0 2.4e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 KEP67386.1 - 7.5e-16 58.3 0.1 2.1e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KEP67386.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 M61 glycyl aminopeptidase SBP_bac_5 PF00496.17 KEP67386.1 - 0.076 11.8 0.1 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF3458 PF11940.3 KEP67387.1 - 1.5e-94 316.8 0.3 2.5e-94 316.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 KEP67387.1 - 7.6e-56 189.8 0.0 1.2e-55 189.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 KEP67387.1 - 2.8e-12 46.7 0.0 7.9e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KEP67387.1 - 0.058 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 M61 glycyl aminopeptidase YhfT PF10797.4 KEP67388.1 - 0.23 10.2 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function Pkinase PF00069.20 KEP67389.1 - 3.1e-47 160.8 0.0 5e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67389.1 - 4.1e-16 58.8 0.0 6.9e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase polyprenyl_synt PF00348.12 KEP67390.1 - 6.3e-43 146.4 0.0 2.3e-21 75.8 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase IMCp PF12314.3 KEP67392.1 - 8.6e-24 83.5 44.4 5e-17 61.8 14.4 2.1 1 1 1 2 2 2 2 Inner membrane complex protein DUF1792 PF08759.6 KEP67392.1 - 0.059 12.9 0.2 0.084 12.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) IMCp PF12314.3 KEP67393.1 - 3.2e-29 100.9 26.4 3.2e-29 100.9 18.3 2.2 1 1 1 2 2 2 2 Inner membrane complex protein Myosin_head PF00063.16 KEP67394.1 - 0.002 16.2 0.0 0.0071 14.4 0.0 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DUF819 PF05684.7 KEP67395.1 - 3.2e-19 69.0 27.4 2.1e-13 49.8 2.2 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF819) Amastin PF07344.6 KEP67395.1 - 1.5 8.3 10.7 0.15 11.6 3.1 2.4 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF3353 PF11833.3 KEP67395.1 - 3.6 6.9 12.3 0.021 14.2 1.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) RRM_1 PF00076.17 KEP67396.1 - 8.7e-44 147.0 0.0 3.4e-22 77.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67396.1 - 1.4e-28 98.6 0.0 8.7e-14 51.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67396.1 - 5e-20 71.0 0.0 4e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KEP67396.1 - 0.011 15.1 0.2 2 7.9 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain HTH_9 PF08221.6 KEP67397.1 - 0.00055 19.7 3.3 0.12 12.2 0.0 3.0 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 KEP67397.1 - 0.044 13.3 0.1 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 MMR_HSR1_C PF08438.5 KEP67400.1 - 1.8e-33 115.0 0.1 2.9e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KEP67400.1 - 1.5e-18 66.8 0.0 4.8e-18 65.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEP67400.1 - 3.6e-09 36.1 1.0 2e-06 27.1 0.1 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KEP67400.1 - 0.0066 16.0 0.6 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TGS PF02824.16 KEP67400.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 TGS domain GTP_EFTU PF00009.22 KEP67400.1 - 0.15 11.5 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain GYF PF02213.11 KEP67401.1 - 7e-13 47.9 0.0 1.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 GYF domain IQ PF00612.22 KEP67401.1 - 0.0019 17.6 0.7 0.0061 16.0 0.5 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF898 PF05987.8 KEP67402.1 - 0.51 9.1 9.4 0.29 9.9 4.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF4013 PF13197.1 KEP67402.1 - 6 6.1 15.2 1.7 7.9 4.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) Shisa PF13908.1 KEP67402.1 - 6.3 6.9 6.8 2.2 8.4 0.9 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator zf-CCCH PF00642.19 KEP67403.1 - 1.1e-05 24.9 13.6 0.035 13.8 0.1 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) mRNA_triPase PF02940.10 KEP67404.1 - 4.8e-21 75.5 0.0 7.8e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Chromate_transp PF02417.10 KEP67404.1 - 0.096 12.2 0.2 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Chromate transporter TFIIS_M PF07500.9 KEP67405.1 - 2.8e-17 62.8 0.7 6e-17 61.7 0.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain DnaJ PF00226.26 KEP67407.1 - 5e-07 29.3 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain PA PF02225.17 KEP67410.1 - 4.6e-12 45.5 0.0 1.1e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF2576 PF10845.3 KEP67410.1 - 0.16 11.1 0.2 0.68 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) RRM_1 PF00076.17 KEP67411.1 - 3.8e-18 64.8 0.0 5.8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67411.1 - 6.5e-16 58.0 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67411.1 - 9.9e-10 38.1 0.1 1.5e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.8 KEP67411.1 - 1e-06 29.2 0.0 1.9e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 SPOC domain BRAP2 PF07576.7 KEP67411.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 BRCA1-associated protein 2 DUF4207 PF13904.1 KEP67412.1 - 4.8 6.4 9.9 4.5 6.5 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF3752 PF12572.3 KEP67413.1 - 1.4e-17 64.2 18.0 1.4e-17 64.2 12.5 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) SR-25 PF10500.4 KEP67413.1 - 0.0013 18.2 29.1 0.0013 18.2 20.2 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Bac_rhamnosid_N PF08531.5 KEP67413.1 - 0.4 10.1 4.8 0.31 10.5 1.3 2.1 2 0 0 2 2 2 0 Alpha-L-rhamnosidase N-terminal domain FancD2 PF14631.1 KEP67413.1 - 1.2 6.1 9.5 1.6 5.6 6.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF1772 PF08592.6 KEP67413.1 - 1.3 8.7 2.8 1.2 8.9 0.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) SOBP PF15279.1 KEP67413.1 - 6.8 6.9 9.3 24 5.2 0.1 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Pap_E4 PF02711.9 KEP67413.1 - 6.8 7.5 6.8 28 5.6 4.7 2.1 1 0 0 1 1 1 0 E4 protein SAG PF04092.8 KEP67414.1 - 7.2e-57 191.1 26.3 2e-33 115.3 6.3 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 KEP67414.1 - 0.031 13.7 2.5 0.75 9.2 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3277) DUF3386 PF11866.3 KEP67414.1 - 0.15 11.2 0.0 14 4.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3386) SAG PF04092.8 KEP67415.1 - 9.3e-57 190.7 17.1 2.2e-31 108.7 2.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 KEP67416.1 - 1.2e-56 190.4 12.8 3.9e-35 120.9 2.9 2.2 2 0 0 2 2 2 2 SRS domain CARM1 PF11531.3 KEP67416.1 - 0.023 14.4 0.4 0.15 11.7 0.0 2.5 3 0 0 3 3 3 0 Coactivator-associated arginine methyltransferase 1 N terminal DUF3277 PF11681.3 KEP67416.1 - 0.045 13.2 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) SAG PF04092.8 KEP67417.1 - 2.3e-59 199.2 22.8 9.1e-36 122.9 3.4 2.1 2 0 0 2 2 2 2 SRS domain ER_lumen_recept PF00810.13 KEP67418.1 - 1.3e-21 77.6 12.5 3.2e-21 76.3 8.7 1.7 1 1 0 1 1 1 1 ER lumen protein retaining receptor DUF3138 PF11336.3 KEP67420.1 - 0.11 10.6 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TRAP_alpha PF03896.11 KEP67421.1 - 0.33 9.8 0.7 0.86 8.5 0.5 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PDEase_I PF00233.14 KEP67422.1 - 4.5e-55 186.9 0.2 7.9e-55 186.1 0.2 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KEP67422.1 - 9.6e-06 25.6 0.0 3.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 HD domain DUF448 PF04296.8 KEP67423.1 - 0.02 14.5 0.0 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF448) RRM_1 PF00076.17 KEP67424.1 - 5.5e-75 246.9 0.3 2.6e-20 71.8 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67424.1 - 2.2e-52 174.9 0.2 7.4e-15 54.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67424.1 - 6.8e-40 134.7 0.0 3.2e-10 39.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KEP67424.1 - 4.4e-31 106.3 2.3 1.1e-30 105.0 1.6 1.8 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KEP67424.1 - 0.00037 20.1 0.0 4.6 7.0 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif ECR1_N PF14382.1 KEP67425.1 - 9.8e-10 37.5 0.1 1.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 KEP67425.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 S1 RNA binding domain Spatacsin_C PF14649.1 KEP67426.1 - 2.6e-21 75.7 0.2 3.4e-12 45.8 0.0 3.2 3 0 0 3 3 3 3 Spatacsin C-terminus FAM165 PF14981.1 KEP67426.1 - 5.6 6.5 0.0 14 5.2 0.0 1.6 1 0 0 1 1 1 0 FAM165 family Kinesin PF00225.18 KEP67427.1 - 1.5e-89 300.0 0.6 2.5e-89 299.3 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain AMP-binding PF00501.23 KEP67428.1 - 2.3e-16 59.2 1.1 1.8e-06 26.6 0.0 4.0 4 0 0 4 4 4 4 AMP-binding enzyme ADK PF00406.17 KEP67429.1 - 1.7e-55 187.0 0.0 2.1e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KEP67429.1 - 1e-13 50.6 0.0 2.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KEP67429.1 - 2.2e-07 30.8 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEP67429.1 - 3.8e-07 30.9 0.1 7.3e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEP67429.1 - 0.0001 22.6 0.0 0.00034 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.4 KEP67429.1 - 0.12 11.2 0.0 0.56 9.0 0.0 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 PspB PF06667.7 KEP67430.1 - 0.075 12.9 3.4 0.55 10.1 0.0 2.7 2 1 0 2 2 2 0 Phage shock protein B Mst1_SARAH PF11629.3 KEP67430.1 - 0.15 11.8 2.1 13 5.6 0.4 2.6 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 TBPIP PF07106.8 KEP67430.1 - 0.16 11.5 10.4 1.1 8.7 1.5 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HTH_1 PF00126.22 KEP67430.1 - 0.19 11.4 3.5 10 5.9 1.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Cep57_MT_bd PF06657.8 KEP67430.1 - 0.84 9.6 11.4 3.5 7.6 0.8 2.9 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_DNA_bd PF12329.3 KEP67430.1 - 1.1 9.0 10.3 0.088 12.6 2.3 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 KEP67430.1 - 3.1 7.6 15.0 0.84 9.5 4.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KEP67430.1 - 3.6 7.1 15.3 4.6 6.7 10.6 1.2 1 0 0 1 1 1 0 IncA protein CutA1 PF03091.10 KEP67431.1 - 1.5e-37 127.2 0.8 2.3e-37 126.7 0.5 1.2 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Phosphodiest PF01663.17 KEP67432.1 - 0.25 10.6 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Cupin_8 PF13621.1 KEP67433.1 - 3.1e-10 39.9 0.0 0.00054 19.5 0.0 2.6 2 0 0 2 2 2 2 Cupin-like domain JmjC PF02373.17 KEP67433.1 - 3.7e-10 40.0 0.1 0.00029 21.0 0.0 2.6 2 0 0 2 2 2 2 JmjC domain, hydroxylase HAP2-GCS1 PF10699.4 KEP67434.1 - 0.034 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Male gamete fusion factor COX17 PF05051.8 KEP67434.1 - 0.37 10.8 3.8 55 3.8 0.0 3.7 4 0 0 4 4 4 0 Cytochrome C oxidase copper chaperone (COX17) PqiA PF04403.8 KEP67435.1 - 2.2e-10 40.3 21.5 0.0028 17.2 0.1 4.5 4 0 0 4 4 4 3 Paraquat-inducible protein A RNase_Zc3h12a PF11977.3 KEP67436.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Pkinase PF00069.20 KEP67437.1 - 2.6e-75 252.9 0.0 3.9e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67437.1 - 8.6e-35 120.0 0.0 1.4e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP67437.1 - 1.4e-29 99.0 8.4 1e-07 30.6 0.6 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP67437.1 - 3.2e-26 91.2 1.1 4.7e-13 49.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP67437.1 - 2.1e-25 86.2 1.7 4.2e-07 29.3 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KEP67437.1 - 1.3e-22 79.1 10.4 2.3e-11 43.1 1.3 4.2 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 KEP67437.1 - 2.8e-21 73.8 8.2 1.6e-07 30.3 0.2 4.7 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KEP67437.1 - 2.9e-07 30.3 0.4 0.00012 21.9 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 KEP67437.1 - 8.6e-06 25.4 0.9 0.14 11.8 0.2 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEP67437.1 - 6.1e-05 23.0 0.6 0.069 13.1 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.18 KEP67437.1 - 0.0049 16.6 0.1 0.039 13.6 0.0 2.5 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEP67437.1 - 0.0076 15.2 0.0 0.018 14.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like DUF1103 PF06513.6 KEP67437.1 - 0.025 13.9 1.3 0.042 13.2 0.9 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) TerB PF05099.8 KEP67437.1 - 0.038 13.7 0.5 0.36 10.5 0.3 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB Kdo PF06293.9 KEP67437.1 - 0.12 11.4 0.0 0.33 9.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_like PF09279.6 KEP67437.1 - 0.15 12.0 0.9 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Sec66 PF09802.4 KEP67438.1 - 2.9e-11 43.1 7.1 4.4e-11 42.5 4.9 1.5 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Mem_trans PF03547.13 KEP67438.1 - 0.34 9.1 1.3 0.52 8.5 0.9 1.2 1 0 0 1 1 1 0 Membrane transport protein Nop52 PF05997.7 KEP67440.1 - 5.9e-25 87.9 0.0 2.2e-24 86.0 0.0 1.8 1 1 0 1 1 1 1 Nucleolar protein,Nop52 L51_S25_CI-B8 PF05047.11 KEP67442.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain EPL1 PF10513.4 KEP67443.1 - 3.9e-09 36.9 3.0 4.4e-09 36.7 0.0 2.7 3 1 0 3 3 3 1 Enhancer of polycomb-like AdoHcyase PF05221.12 KEP67447.1 - 3.4e-132 439.3 0.0 4e-132 439.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KEP67447.1 - 5e-79 263.8 1.2 7.7e-79 263.2 0.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KEP67447.1 - 1e-09 37.8 0.2 1.8e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEP67447.1 - 0.00012 22.2 0.2 0.00024 21.3 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding IlvN PF07991.7 KEP67447.1 - 0.00012 21.4 0.2 0.00021 20.6 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain THF_DHG_CYH_C PF02882.14 KEP67447.1 - 0.0002 20.5 1.0 0.00088 18.3 0.7 2.0 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.13 KEP67447.1 - 0.00067 19.6 0.4 0.0024 17.8 0.3 1.9 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 KEP67447.1 - 0.0023 18.0 0.2 0.0056 16.7 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TMEM107 PF14995.1 KEP67447.1 - 0.0046 17.0 0.4 0.0086 16.1 0.3 1.4 1 0 0 1 1 1 1 Transmembrane protein ELFV_dehydrog PF00208.16 KEP67447.1 - 0.0048 16.5 0.9 0.012 15.1 0.3 1.7 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KEP67447.1 - 0.019 14.5 1.5 0.045 13.3 0.7 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KEP67447.1 - 0.039 13.6 0.5 0.068 12.8 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thioredoxin_8 PF13905.1 KEP67448.1 - 1.3e-27 95.7 0.0 2.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like PUB PF09409.5 KEP67448.1 - 1.8e-11 43.6 0.1 4.2e-11 42.4 0.0 1.6 2 0 0 2 2 2 1 PUB domain Thioredoxin_2 PF13098.1 KEP67448.1 - 1.4e-09 38.1 0.0 2.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 KEP67448.1 - 6.1e-09 35.5 0.0 8.8e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.16 KEP67448.1 - 3.2e-07 30.0 0.0 5.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEP67448.1 - 1.7e-06 27.6 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 KEP67448.1 - 0.0005 19.6 0.0 0.0061 16.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KEP67448.1 - 0.0018 18.2 0.0 0.0044 17.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 KEP67448.1 - 0.084 12.8 0.0 0.34 10.9 0.0 2.1 1 0 0 1 1 1 0 Glutaredoxin Nebulin PF00880.13 KEP67449.1 - 0.12 12.0 0.8 3.4 7.4 0.0 2.8 2 0 0 2 2 2 0 Nebulin repeat Ribosomal_S13 PF00416.17 KEP67450.1 - 2.8e-37 127.4 1.7 3.6e-37 127.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KEP67450.1 - 0.0032 16.0 0.0 0.0032 16.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) SecA_SW PF07516.8 KEP67450.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Rad17 PF03215.10 KEP67454.1 - 0.24 10.0 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Snf7 PF03357.16 KEP67455.1 - 1.1e-09 37.8 0.1 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Snf7 AP2 PF00847.15 KEP67456.1 - 3.6e-08 33.4 1.4 8.1e-08 32.2 1.0 1.6 1 0 0 1 1 1 1 AP2 domain S1 PF00575.18 KEP67458.1 - 1.2e-21 76.5 5.2 2.1e-07 30.9 0.4 10.8 11 1 0 11 11 11 3 S1 RNA binding domain TPR_14 PF13428.1 KEP67458.1 - 1.7e-05 25.0 0.2 0.51 11.1 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEP67458.1 - 0.00023 21.4 0.2 6.5 7.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat SPT6_acidic PF14632.1 KEP67458.1 - 0.00078 19.5 10.3 0.00078 19.5 7.1 6.9 7 0 0 7 7 7 1 Acidic N-terminal SPT6 TPR_6 PF13174.1 KEP67458.1 - 0.02 15.3 2.0 0.86 10.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.9 KEP67458.1 - 0.78 9.4 12.6 1.5 8.5 0.4 3.7 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) SOBP PF15279.1 KEP67458.1 - 8.9 6.5 6.9 8.3 6.6 2.8 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein DUF2360 PF10152.4 KEP67459.1 - 0.14 12.4 6.0 0.7 10.1 0.0 4.1 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) HHH_5 PF14520.1 KEP67459.1 - 1.1 9.4 4.4 0.35 11.0 0.3 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain BT1 PF03092.11 KEP67460.1 - 4.1e-70 236.6 18.9 5.9e-70 236.1 13.1 1.2 1 0 0 1 1 1 1 BT1 family Phage_glycop_gL PF11108.3 KEP67461.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Viral glycoprotein L IF3_C PF00707.17 KEP67461.1 - 0.22 11.2 2.0 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain Aldedh PF00171.17 KEP67462.1 - 0.0039 15.5 0.2 0.0058 15.0 0.2 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RskA PF10099.4 KEP67462.1 - 0.64 9.7 4.2 0.28 10.8 1.0 1.9 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF2975 PF11188.3 KEP67463.1 - 0.032 13.9 0.3 0.037 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Ins_P5_2-kin PF06090.7 KEP67464.1 - 2.7e-16 59.5 0.5 2.2e-07 30.2 0.0 4.5 4 1 0 4 4 4 2 Inositol-pentakisphosphate 2-kinase CAP PF00188.21 KEP67468.1 - 1.3e-08 35.3 0.2 2.3e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2249 PF10006.4 KEP67468.1 - 0.13 11.8 1.0 54 3.4 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2249) Ribosomal_L13 PF00572.13 KEP67470.1 - 5.4e-36 123.4 0.0 7.7e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Peptidase_C33 PF05412.7 KEP67470.1 - 0.087 12.6 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase Ribosomal_L14 PF00238.14 KEP67471.1 - 4.3e-26 91.0 0.6 5e-26 90.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_pol_Rpb1_5 PF04998.12 KEP67472.1 - 9.6e-100 333.3 0.0 1.5e-99 332.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KEP67472.1 - 2e-98 329.7 0.0 3.6e-98 328.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KEP67472.1 - 4.4e-66 221.9 0.0 8.5e-66 220.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KEP67472.1 - 1.3e-46 158.7 2.1 2.3e-46 157.9 1.2 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KEP67472.1 - 2.1e-45 154.2 0.0 4.3e-45 153.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KEP67472.1 - 2.8e-42 143.6 3.0 3.1e-42 143.4 0.4 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KEP67472.1 - 1.8e-39 133.7 0.1 4.7e-39 132.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Motile_Sperm PF00635.21 KEP67474.1 - 0.12 12.0 0.0 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 MSP (Major sperm protein) domain GDA1_CD39 PF01150.12 KEP67475.1 - 1.1e-47 162.5 0.0 2.8e-45 154.6 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family DUF3220 PF11516.3 KEP67475.1 - 0.052 13.5 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) ATP-synt_D PF01813.12 KEP67476.1 - 0.0014 18.1 7.5 0.0014 18.1 5.2 2.2 1 1 1 2 2 2 1 ATP synthase subunit D Lzipper-MIP1 PF14389.1 KEP67476.1 - 0.0048 16.9 12.5 0.19 11.8 2.6 2.5 2 0 0 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 Spherulin4 PF12138.3 KEP67476.1 - 0.035 13.5 1.6 0.05 13.0 1.1 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 DUF4613 PF15390.1 KEP67476.1 - 0.98 7.5 7.4 1.2 7.2 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF3584 PF12128.3 KEP67476.1 - 1.7 5.8 24.4 2.2 5.5 16.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.7 KEP67476.1 - 1.9 6.7 3.3 2.3 6.5 2.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HCMV_UL139 PF12507.3 KEP67476.1 - 2.2 8.4 14.3 0.23 11.6 2.2 2.3 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein NusB PF01029.13 KEP67476.1 - 2.4 8.1 10.4 1.6 8.6 3.1 2.2 1 1 1 2 2 2 0 NusB family Macoilin PF09726.4 KEP67476.1 - 2.6 6.2 19.6 3.1 5.9 13.6 1.1 1 0 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 KEP67476.1 - 3 7.7 24.9 0.89 9.4 4.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1911 PF08929.5 KEP67476.1 - 3 8.5 9.2 0.6 10.8 2.9 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1911) TPR_MLP1_2 PF07926.7 KEP67476.1 - 3 7.5 28.9 0.28 10.9 6.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 KEP67476.1 - 3.5 6.7 26.9 7.2 5.7 0.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 KEP67476.1 - 3.7 7.0 35.1 11 5.5 13.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4407 PF14362.1 KEP67476.1 - 7.8 5.3 15.6 13 4.6 10.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.4 KEP67476.1 - 9.6 6.0 29.6 3.5 7.4 15.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ArfGap PF01412.13 KEP67477.1 - 6.8e-34 116.1 0.1 1.3e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CAP_N PF01213.14 KEP67477.1 - 2.6 7.2 5.9 0.22 10.7 0.1 1.9 2 1 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Chlam_vir PF05475.6 KEP67478.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D DUF2580 PF10824.3 KEP67478.1 - 2.5 8.5 6.8 0.67 10.3 1.8 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2580) P2X_receptor PF00864.14 KEP67479.1 - 0.058 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP P2X receptor Sec3_C_2 PF15278.1 KEP67481.1 - 6.7 6.9 8.5 5 7.3 0.5 3.7 2 0 0 2 2 2 0 Sec3 exocyst complex subunit TMEM18 PF14770.1 KEP67482.1 - 6.1e-05 22.5 8.2 0.00019 20.9 5.7 1.7 1 1 0 1 1 1 1 Transmembrane protein 18 DUF4131 PF13567.1 KEP67482.1 - 3.3 7.0 10.8 11 5.4 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF605 PF04652.11 KEP67482.1 - 3.8 6.8 6.1 6.1 6.1 4.3 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KEP67483.1 - 0.0018 18.2 5.0 0.0029 17.5 3.4 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 KEP67483.1 - 5.8 6.2 19.4 17 4.7 13.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Histone PF00125.19 KEP67487.1 - 9.5e-22 76.9 0.3 2.6e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 AMMECR1 PF01871.12 KEP67488.1 - 8.1e-31 106.4 0.0 1e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 HIT PF01230.18 KEP67489.1 - 2.8e-10 40.5 0.0 4.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain Gtr1_RagA PF04670.7 KEP67490.1 - 4.1e-73 245.3 0.0 1.4e-37 129.1 0.1 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Arf PF00025.16 KEP67490.1 - 0.00025 20.3 0.0 0.00063 19.0 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 KEP67490.1 - 0.0046 17.4 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 KEP67490.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Ras PF00071.17 KEP67490.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras family AIG1 PF04548.11 KEP67490.1 - 0.18 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family PMSR PF01625.16 KEP67494.1 - 1.8e-52 177.3 0.1 2.5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PepSY_TM_1 PF13172.1 KEP67494.1 - 2.3 8.0 6.7 0.47 10.2 0.2 2.3 2 0 0 2 2 2 0 PepSY-associated TM helix V-ATPase_G PF03179.10 KEP67495.1 - 0.00035 20.8 6.3 0.00072 19.8 4.3 1.5 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Transposase_22 PF02994.9 KEP67495.1 - 0.028 12.9 2.4 0.045 12.2 1.7 1.2 1 0 0 1 1 1 0 L1 transposable element Mt_ATP-synt_B PF05405.9 KEP67495.1 - 0.12 11.8 2.3 0.2 11.0 1.6 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pkinase PF00069.20 KEP67496.1 - 1.1e-71 241.0 0.0 1.5e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67496.1 - 1.5e-29 102.8 0.0 2.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 KEP67496.1 - 4.1e-24 82.0 0.1 8.5e-06 24.7 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEP67496.1 - 9.9e-22 76.8 0.2 1.9e-09 37.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEP67496.1 - 2.2e-19 67.5 0.1 0.0003 20.4 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEP67496.1 - 1.6e-17 61.9 0.7 1.8e-05 23.8 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KEP67496.1 - 4.3e-17 61.4 1.2 0.00012 21.6 0.1 4.3 2 1 2 4 4 4 4 EF-hand domain pair CBM_20 PF00686.14 KEP67496.1 - 4.4e-13 48.6 0.1 7.9e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain SPARC_Ca_bdg PF10591.4 KEP67496.1 - 2.6e-06 27.4 0.0 0.00089 19.2 0.0 2.4 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KEP67496.1 - 0.00015 21.4 0.0 0.079 12.7 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.9 KEP67496.1 - 0.0011 18.0 0.0 0.0027 16.8 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.1 KEP67496.1 - 0.024 14.5 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Kinase-like PF14531.1 KEP67496.1 - 0.058 12.3 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Kinase-like DUF2807 PF10988.3 KEP67496.1 - 0.089 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2807) SYS1 PF09801.4 KEP67497.1 - 1.9e-31 108.9 5.4 5.4e-27 94.5 1.1 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network RAP PF08373.5 KEP67499.1 - 2.2e-13 49.7 0.0 4.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 RAP domain Zip PF02535.17 KEP67500.1 - 6.7e-30 104.1 14.6 1.2e-18 67.2 4.9 3.0 4 0 0 4 4 4 2 ZIP Zinc transporter Kua-UEV1_localn PF10520.4 KEP67500.1 - 4.9 6.7 13.5 1.4 8.4 0.0 3.3 3 0 0 3 3 3 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF3457 PF11939.3 KEP67501.1 - 0.086 12.3 0.2 0.086 12.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3457) PS_Dcarbxylase PF02666.10 KEP67502.1 - 2.9e-57 193.2 0.1 5e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 KEP67502.1 - 0.21 11.6 0.8 12 6.0 0.0 3.3 3 1 1 4 4 4 0 Peptidase family M23 Form-deh_trans PF09163.6 KEP67502.1 - 0.53 9.8 2.8 0.5 9.9 0.5 2.0 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Trans_reg_C PF00486.23 KEP67505.1 - 0.0024 17.7 2.2 1.5 8.7 0.1 4.0 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal DUF948 PF06103.6 KEP67505.1 - 0.032 14.1 0.1 0.032 14.1 0.0 8.6 4 2 4 9 9 9 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 KEP67505.1 - 0.055 13.0 0.3 0.055 13.0 0.2 7.6 2 1 5 7 7 7 0 IncA protein Filament PF00038.16 KEP67505.1 - 0.075 12.4 109.0 0.18 11.2 9.8 5.5 2 1 3 6 6 6 0 Intermediate filament protein LPP PF04728.8 KEP67505.1 - 9.5 6.1 18.2 0.29 10.9 0.3 4.4 5 0 0 5 5 5 0 Lipoprotein leucine-zipper PDZ_2 PF13180.1 KEP67506.1 - 0.00015 21.5 0.0 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.9 KEP67506.1 - 0.022 14.7 0.0 0.072 13.0 0.0 1.7 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain DUF2063 PF09836.4 KEP67506.1 - 0.051 13.5 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) PDZ PF00595.19 KEP67506.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Kinocilin PF15033.1 KEP67506.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinocilin protein SAP30_Sin3_bdg PF13867.1 KEP67508.1 - 0.067 13.0 0.1 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Tim17 PF02466.14 KEP67510.1 - 1.4e-28 99.4 4.2 1.8e-28 99.1 2.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Chorein_N PF12624.2 KEP67513.1 - 3.4e-09 36.2 0.0 7.4e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KEP67513.1 - 0.0024 17.9 0.0 0.0093 16.1 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain CAGE1 PF15066.1 KEP67513.1 - 9.6 4.5 3.7 18 3.6 2.6 1.3 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family Pkinase_Tyr PF07714.12 KEP67514.1 - 7.1e-39 133.4 0.0 9.9e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KEP67514.1 - 1.5e-37 129.2 0.0 2.3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEP67514.1 - 0.023 14.4 0.1 0.023 14.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Thioredoxin_8 PF13905.1 KEP67516.1 - 4.6e-21 74.7 0.0 6.2e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like ABC_tran PF00005.22 KEP67517.1 - 2e-18 67.0 0.0 3.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KEP67517.1 - 1.6e-06 27.5 0.2 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEP67517.1 - 2.2e-06 27.8 0.1 3e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 KEP67517.1 - 0.0028 16.2 0.0 0.0039 15.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEP67517.1 - 0.0037 16.7 0.1 0.0086 15.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KEP67517.1 - 0.0047 17.7 0.2 0.013 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEP67517.1 - 0.0057 16.0 0.0 0.096 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEP67517.1 - 0.0091 15.1 0.1 0.21 10.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MutS_V PF00488.16 KEP67517.1 - 0.025 14.0 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 MutS domain V DUF1129 PF06570.6 KEP67519.1 - 0.0096 15.2 3.1 0.02 14.2 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Wzy_C PF04932.10 KEP67519.1 - 1.1 9.0 5.8 2.2 8.0 4.0 1.5 1 0 0 1 1 1 0 O-Antigen ligase VIT1 PF01988.14 KEP67519.1 - 1.9 7.8 10.0 0.12 11.8 2.5 2.0 2 0 0 2 2 2 0 VIT family LMBR1 PF04791.11 KEP67520.1 - 1.5 7.3 3.7 2.2 6.7 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SR-25 PF10500.4 KEP67521.1 - 0.075 12.5 13.3 0.12 11.8 9.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_M28 PF04389.12 KEP67522.1 - 2.5e-19 69.7 0.0 4.7e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 UbiA PF01040.13 KEP67523.1 - 0.43 9.7 0.0 0.67 9.1 0.0 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family Epimerase PF01370.16 KEP67526.1 - 9.5e-52 175.7 0.0 1.2e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KEP67526.1 - 1.5e-25 88.8 0.1 2.6e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KEP67526.1 - 1.2e-16 60.3 0.0 2.4e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEP67526.1 - 3.7e-14 52.2 0.0 5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KEP67526.1 - 4.7e-14 51.9 0.0 1.1e-13 50.7 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEP67526.1 - 1.6e-12 46.9 0.0 4.1e-12 45.5 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEP67526.1 - 1.8e-12 47.6 0.0 1.8e-10 41.0 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEP67526.1 - 1.3e-09 38.1 0.0 4.6e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEP67526.1 - 0.0001 22.0 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 KEP67526.1 - 0.00079 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KEP67526.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KEP67526.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 KEP67526.1 - 0.04 12.9 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase PWWP PF00855.12 KEP67527.1 - 1.7e-05 24.9 0.1 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 PWWP domain TIM PF00121.13 KEP67531.1 - 1e-88 296.5 0.0 1.1e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Herpes_UL37_2 PF07413.6 KEP67531.1 - 0.061 12.1 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 zf-CCCH PF00642.19 KEP67533.1 - 1.8 8.3 9.8 0.57 9.9 0.4 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_8 PF13855.1 KEP67535.1 - 3.1e-08 33.2 1.4 0.00011 21.8 0.0 3.8 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KEP67535.1 - 3.5e-06 26.5 3.2 1.2 9.3 0.1 4.9 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 KEP67535.1 - 4.9e-06 25.8 4.7 5.6 7.6 0.1 5.3 5 0 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 KEP67535.1 - 1.8e-05 24.1 1.3 2.2 8.6 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.2 KEP67535.1 - 6.9e-05 22.3 1.3 0.14 11.8 0.0 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) Pkinase PF00069.20 KEP67536.1 - 4.4e-44 150.5 0.0 5e-43 147.1 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67536.1 - 2e-16 59.8 0.0 1.2e-14 54.0 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase HD PF01966.17 KEP67536.1 - 0.78 9.7 0.2 52 3.8 0.1 2.3 2 0 0 2 2 2 0 HD domain Kinase-like PF14531.1 KEP67536.1 - 6.4 5.6 0.0 12 4.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Med31 PF05669.7 KEP67537.1 - 3e-33 113.6 2.0 4.5e-33 113.0 1.4 1.2 1 0 0 1 1 1 1 SOH1 Acyl_transf_1 PF00698.16 KEP67539.1 - 1.8e-21 76.7 3.5 3.6e-15 56.1 2.6 2.4 3 0 0 3 3 3 2 Acyl transferase domain ATP-synt_DE_N PF02823.11 KEP67540.1 - 7.6e-12 44.8 0.0 1.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Pterin_4a PF01329.14 KEP67541.1 - 1.8e-31 107.7 0.9 2e-31 107.6 0.6 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase MFS_2 PF13347.1 KEP67542.1 - 1.2e-60 205.1 34.1 1.5e-60 204.7 23.6 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Pkinase PF00069.20 KEP67544.1 - 2e-65 220.5 0.0 2.3e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67544.1 - 1.2e-35 122.8 0.0 1.6e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP67544.1 - 8.6e-08 31.4 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 KEP67544.1 - 0.04 14.4 0.6 0.089 13.3 0.4 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.18 KEP67544.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-hand_6 PF13405.1 KEP67546.1 - 2.2e-07 30.1 0.0 0.015 15.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.1 KEP67546.1 - 4.3e-06 26.5 0.1 0.053 13.4 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KEP67546.1 - 4.6e-06 25.5 0.1 0.044 13.0 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KEP67546.1 - 0.0001 22.3 0.0 0.033 14.3 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KEP67546.1 - 0.00081 18.9 2.2 0.45 10.1 0.0 3.9 2 1 1 3 3 3 1 EF-hand domain pair Lact_bio_phlase PF09508.5 KEP67546.1 - 0.071 10.7 0.0 0.089 10.4 0.0 1.0 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase IBR PF01485.16 KEP67547.1 - 3.9e-05 23.4 11.7 3.9e-05 23.4 8.1 4.6 5 1 0 5 5 5 2 IBR domain Aa_trans PF01490.13 KEP67548.1 - 1.8e-52 178.2 6.5 1.5e-50 171.8 0.1 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEP67548.1 - 0.00011 21.2 4.8 0.00018 20.4 3.3 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DnaJ PF00226.26 KEP67549.1 - 9.2e-20 70.1 0.1 1.9e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_60s PF00428.14 KEP67549.1 - 2.7 8.4 12.0 0.066 13.6 3.4 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Metallophos PF00149.23 KEP67550.1 - 0.018 14.4 0.5 0.038 13.3 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase PAP_central PF04928.12 KEP67551.1 - 7.2e-93 310.0 0.0 9.9e-93 309.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KEP67551.1 - 2.3e-22 79.2 0.0 1.7e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KEP67551.1 - 1.4e-10 41.3 0.0 3.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SR-25 PF10500.4 KEP67551.1 - 0.027 13.9 5.3 0.044 13.2 3.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4269 PF14091.1 KEP67551.1 - 0.15 11.9 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) DUF755 PF05501.6 KEP67551.1 - 0.95 9.5 6.8 1.6 8.7 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Helicase_C PF00271.26 KEP67552.1 - 7.1e-26 89.8 0.0 3.4e-24 84.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEP67552.1 - 8.1e-26 90.5 0.0 3.8e-25 88.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1253 PF06862.7 KEP67552.1 - 0.18 10.1 0.0 7.3 4.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) E1-E2_ATPase PF00122.15 KEP67553.1 - 7.7e-36 123.2 0.1 1.8e-25 89.3 0.0 2.4 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 KEP67553.1 - 8e-25 88.5 5.7 2.3e-11 44.5 0.0 4.1 5 0 0 5 5 5 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEP67553.1 - 8.2e-13 48.9 0.0 1.5e-10 41.5 0.0 3.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEP67553.1 - 1.5e-09 37.8 0.1 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KEP67553.1 - 0.14 11.7 0.1 0.62 9.5 0.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RNase_HII PF01351.13 KEP67554.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 Ribonuclease HII IMCp PF12314.3 KEP67555.1 - 4.3e-16 58.8 125.5 8.1e-09 35.5 16.5 5.9 1 1 4 5 5 5 3 Inner membrane complex protein zf-C2H2_jaz PF12171.3 KEP67557.1 - 2.7e-11 43.2 1.4 4.1e-11 42.6 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KEP67557.1 - 0.00074 19.5 0.2 0.0012 18.8 0.1 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KEP67557.1 - 0.0022 18.1 0.3 0.0034 17.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 KEP67557.1 - 0.013 14.9 0.2 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger Exonuc_VIII PF06630.6 KEP67557.1 - 0.025 13.9 0.0 0.036 13.3 0.0 1.5 1 1 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII DUF2616 PF11077.3 KEP67559.1 - 0.19 11.1 2.3 0.18 11.2 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) DEAD PF00270.24 KEP67560.1 - 3.7e-46 156.6 0.0 1.5e-45 154.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEP67560.1 - 2.4e-27 94.6 0.0 5e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Thioredoxin_8 PF13905.1 KEP67560.1 - 0.0081 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DUF1253 PF06862.7 KEP67560.1 - 0.019 13.3 0.0 0.041 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Peptidase_S8 PF00082.17 KEP67561.1 - 0.086 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Subtilase family DUF2053 PF09767.4 KEP67562.1 - 2.2e-30 105.7 7.6 2.9e-30 105.3 5.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) SieB PF14163.1 KEP67562.1 - 0.29 10.7 1.8 6.3 6.3 0.1 2.4 2 0 0 2 2 2 0 Superinfection exclusion protein B PgaD PF13994.1 KEP67562.1 - 2 7.9 5.9 0.35 10.3 0.3 2.3 1 1 1 2 2 2 0 PgaD-like protein Ribosomal_L28 PF00830.14 KEP67563.1 - 3e-06 26.9 0.2 7.1e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal L28 family AAA_23 PF13476.1 KEP67564.1 - 4.9 7.4 8.8 6.9 6.9 6.1 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 KEP67564.1 - 5.2 5.9 16.9 7.1 5.4 11.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 adh_short_C2 PF13561.1 KEP67565.1 - 5.7e-28 98.3 0.8 1.2e-17 64.5 0.4 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEP67565.1 - 9.9e-21 74.3 1.7 3e-19 69.5 1.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEP67565.1 - 3.5e-06 26.8 0.9 6.3e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.12 KEP67565.1 - 9.2e-05 22.8 0.2 0.00018 21.8 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KEP67565.1 - 0.004 17.2 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KEP67565.1 - 0.004 16.0 0.1 0.0067 15.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KEP67565.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 KEP67565.1 - 0.038 12.9 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 KEP67565.1 - 0.12 12.0 1.0 0.37 10.4 0.2 2.0 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-CCCH PF00642.19 KEP67566.1 - 6.4e-09 35.2 17.0 0.0026 17.3 1.4 4.0 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF674 PF05056.7 KEP67566.1 - 2.7 6.5 2.9 6.4 5.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF674) RRM_6 PF14259.1 KEP67567.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67567.1 - 0.049 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEP67567.1 - 0.14 11.7 0.0 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mcp5_PH PF12814.2 KEP67569.1 - 0.0066 16.3 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology V_ATPase_I PF01496.14 KEP67569.1 - 6.3 4.5 8.8 13 3.5 6.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DAGAT PF03982.8 KEP67571.1 - 2.3e-76 256.3 0.0 3.1e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 KEP67571.1 - 0.0025 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase eIF3_subunit PF08597.5 KEP67572.1 - 0.058 12.9 3.6 0.092 12.3 2.5 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cortex-I_coil PF09304.5 KEP67572.1 - 0.24 11.4 5.2 0.08 12.9 1.2 1.9 1 1 0 1 1 1 0 Cortexillin I, coiled coil FliT PF05400.8 KEP67572.1 - 7.5 7.0 9.9 17 5.8 5.2 2.7 1 1 1 2 2 2 0 Flagellar protein FliT Abhydrolase_6 PF12697.2 KEP67575.1 - 1.6e-10 41.2 0.0 1.3e-08 34.9 0.0 3.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEP67575.1 - 5.4e-10 38.9 1.4 4e-08 32.9 0.0 3.0 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KEP67575.1 - 4.5e-09 36.2 0.0 2.5e-08 33.8 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Radical_SAM PF04055.16 KEP67576.1 - 1.9e-12 47.6 0.0 8.3e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily EF1_GNE PF00736.14 KEP67577.1 - 3.1e-27 94.0 2.2 3.1e-27 94.0 1.5 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain SmpA_OmlA PF04355.8 KEP67577.1 - 0.07 12.7 0.1 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 SmpA / OmlA family Peptidase_M3 PF01432.15 KEP67578.1 - 2.9e-27 95.8 0.5 6.7e-25 88.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M3_N PF08439.5 KEP67578.1 - 1.6e-05 24.8 0.0 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 1 Oligopeptidase F DUF4003 PF13170.1 KEP67578.1 - 0.083 12.1 0.9 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) Reticulon PF02453.12 KEP67579.1 - 3.2e-22 78.9 5.3 4.1e-22 78.5 3.6 1.2 1 0 0 1 1 1 1 Reticulon p53-inducible11 PF14936.1 KEP67579.1 - 0.32 10.9 2.6 0.35 10.7 1.1 1.6 1 1 0 2 2 2 0 Tumour protein p53-inducible protein 11 SNF2_N PF00176.18 KEP67580.1 - 8.2e-58 195.5 0.0 1.6e-27 96.1 0.0 3.4 3 0 0 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.26 KEP67580.1 - 1.9e-12 46.8 0.0 3.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KEP67580.1 - 6.1e-10 38.7 1.7 2.1e-09 37.0 1.2 2.0 1 0 0 1 1 1 1 Ring finger domain UBA PF00627.26 KEP67580.1 - 4.6e-06 26.3 0.1 1.5e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain SAP PF02037.22 KEP67580.1 - 1e-05 24.8 0.0 3.8e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 SAP domain zf-PARP PF00645.13 KEP67580.1 - 3.1e-05 24.1 0.0 8.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C2HC_2 PF13913.1 KEP67580.1 - 0.0003 20.3 0.1 0.0003 20.3 0.1 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C3HC4 PF00097.20 KEP67580.1 - 0.001 18.6 1.0 0.001 18.6 0.7 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KEP67580.1 - 0.058 13.3 1.2 0.43 10.5 1.1 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 KEP67580.1 - 8.1 6.5 11.1 0.066 13.2 0.9 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_2 PF02230.11 KEP67583.1 - 0.13 11.6 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1980 PF09323.5 KEP67583.1 - 0.58 9.8 0.9 3.1 7.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Topoisom_bac PF01131.15 KEP67584.1 - 4.3e-97 325.4 0.0 5.3e-97 325.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 KEP67584.1 - 4.5e-16 58.6 0.0 7.6e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Sec23_trunk PF04811.10 KEP67587.1 - 6.9e-24 84.5 0.0 2.7e-23 82.6 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEP67587.1 - 3.4e-22 77.8 0.0 7.6e-22 76.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KEP67587.1 - 1.6e-11 43.5 4.1 3.3e-11 42.5 2.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KEP67587.1 - 8.9e-08 32.5 0.1 1.3e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain LSM PF01423.17 KEP67589.1 - 6.4e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 KEP67591.1 - 2.9e-47 161.0 0.0 3.6e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67591.1 - 1.4e-18 66.9 0.0 1.9e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEP67591.1 - 1.1e-05 24.5 0.1 3.5e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEP67591.1 - 0.00037 20.3 0.0 0.00094 18.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEP67591.1 - 0.00071 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KEP67591.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 KEP67591.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Herpes_glycop PF01528.11 KEP67591.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M RabGAP-TBC PF00566.13 KEP67592.1 - 3.2e-21 75.7 0.0 5.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-CCCH PF00642.19 KEP67593.1 - 3.8e-09 36.0 2.9 8e-09 34.9 2.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 KEP67593.1 - 3.8e-07 29.7 9.3 6.9e-07 28.8 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEP67593.1 - 3.2e-06 27.0 10.0 6.4e-06 26.0 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEP67593.1 - 5.9e-06 25.8 5.6 1.1e-05 24.9 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP67593.1 - 2.3e-05 24.1 8.8 3.8e-05 23.4 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KEP67593.1 - 0.00019 21.0 2.1 0.00049 19.7 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KEP67593.1 - 0.013 15.1 10.5 0.034 13.7 7.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 KEP67593.1 - 0.15 11.9 4.3 0.54 10.1 1.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.1 KEP67593.1 - 0.18 11.7 10.2 0.088 12.6 3.9 2.5 1 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KEP67593.1 - 2.7 7.5 6.0 5.5 6.5 4.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger Troponin-I_N PF11636.3 KEP67595.1 - 1.8 8.3 7.2 0.094 12.4 0.8 2.0 2 0 0 2 2 2 0 Troponin I residues 1-32 SAG PF04092.8 KEP67596.1 - 1e-06 29.1 2.8 1.3e-06 28.7 2.0 1.1 1 0 0 1 1 1 1 SRS domain SNARE PF05739.14 KEP67598.1 - 2.2e-13 49.6 5.3 6.6e-13 48.1 2.5 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KEP67598.1 - 1.3e-11 44.5 1.3 1.3e-11 44.5 0.9 2.2 2 0 0 2 2 2 1 Syntaxin Vac_Fusion PF02346.11 KEP67598.1 - 0.0087 15.4 1.7 0.15 11.5 0.1 3.0 3 0 0 3 3 3 1 Chordopoxvirus fusion protein HSBP1 PF06825.7 KEP67598.1 - 0.043 13.3 2.7 0.26 10.9 0.8 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Tup_N PF08581.5 KEP67598.1 - 0.079 13.1 8.1 0.081 13.1 0.9 2.7 2 1 0 2 2 2 0 Tup N-terminal Cauli_AT PF03233.8 KEP67598.1 - 0.13 11.9 1.4 7.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Aphid transmission protein SF-assemblin PF06705.6 KEP67598.1 - 0.13 11.3 5.4 0.11 11.6 0.5 2.2 2 0 0 2 2 2 0 SF-assemblin/beta giardin zf-C4H2 PF10146.4 KEP67598.1 - 0.25 11.3 2.9 0.84 9.6 0.1 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein DUF2721 PF11026.3 KEP67598.1 - 0.33 10.5 5.0 0.12 12.0 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) Rho_N PF07498.7 KEP67598.1 - 0.66 9.7 3.3 0.4 10.4 0.2 2.2 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain DUF310 PF03750.8 KEP67598.1 - 0.79 9.9 4.4 0.79 9.9 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF310) Syntaxin-6_N PF09177.6 KEP67598.1 - 0.8 10.1 4.8 13 6.2 0.2 2.9 2 1 2 4 4 4 0 Syntaxin 6, N-terminal DUF148 PF02520.12 KEP67598.1 - 1.6 8.5 6.0 1 9.2 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.7 KEP67598.1 - 3.3 7.5 8.0 1.8 8.4 0.6 2.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CEP76-C2 PF15627.1 KEP67599.1 - 5.4e-23 81.2 0.0 9.3e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain Yippee-Mis18 PF03226.9 KEP67601.1 - 3.1e-19 68.8 0.4 3.7e-19 68.5 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_6 PF14599.1 KEP67601.1 - 0.023 14.5 1.3 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon GFA PF04828.9 KEP67601.1 - 0.025 14.4 1.3 0.36 10.8 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 KEP67601.1 - 0.026 14.8 0.3 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF3268 PF11672.3 KEP67601.1 - 0.033 14.2 0.6 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Elf1 PF05129.8 KEP67601.1 - 0.043 13.5 0.3 4.2 7.1 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 KEP67601.1 - 0.084 12.7 1.8 3.7 7.4 1.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 KEP67601.1 - 0.46 9.9 3.3 6.6 6.2 0.0 2.5 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit AF-4 PF05110.8 KEP67605.1 - 0.03 12.2 20.8 0.014 13.3 12.6 1.7 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF2217 PF10265.4 KEP67605.1 - 1.9 7.1 12.3 3.7 6.1 8.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SNase PF00565.12 KEP67606.1 - 2.9e-22 78.9 0.0 2.2e-14 53.5 0.0 2.4 2 0 0 2 2 2 2 Staphylococcal nuclease homologue TrbC PF04956.8 KEP67607.1 - 0.015 15.2 0.4 0.02 14.8 0.3 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family AgrB PF04647.10 KEP67607.1 - 0.027 13.5 0.2 0.035 13.1 0.1 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Oxidored_q1 PF00361.15 KEP67607.1 - 0.035 13.3 0.7 0.04 13.1 0.5 1.1 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains DUF3522 PF12036.3 KEP67608.1 - 4.7e-21 75.4 6.2 8.6e-21 74.5 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF3639 PF12341.3 KEP67608.1 - 0.077 13.0 1.5 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) Translin PF01997.11 KEP67609.1 - 1.3e-30 106.4 0.1 1.9e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Translin family C_GCAxxG_C_C PF09719.5 KEP67609.1 - 0.038 13.8 0.2 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Aconitase PF00330.15 KEP67610.1 - 4.2e-144 480.4 0.0 5.2e-144 480.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEP67610.1 - 1.4e-42 144.9 0.0 2.3e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-RING_2 PF13639.1 KEP67611.1 - 3.5e-13 49.1 6.6 9.6e-13 47.7 4.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEP67611.1 - 8e-08 32.1 6.7 2.2e-07 30.7 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEP67611.1 - 2e-07 30.9 4.4 4.4e-07 29.9 3.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEP67611.1 - 2.8e-05 23.6 4.6 7e-05 22.4 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP67611.1 - 0.00052 19.6 4.5 0.0013 18.4 3.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEP67611.1 - 0.00054 19.5 7.2 0.0014 18.2 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KEP67611.1 - 0.00067 19.3 2.0 0.00067 19.3 1.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 KEP67611.1 - 0.019 14.7 3.6 0.06 13.1 2.5 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEP67611.1 - 0.27 10.8 5.3 0.86 9.2 3.7 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-DHHC PF01529.15 KEP67611.1 - 2.7 7.3 7.3 0.16 11.3 0.5 2.0 1 1 1 2 2 2 0 DHHC palmitoyltransferase zf-MYND PF01753.13 KEP67611.1 - 5 7.0 7.5 1.8 8.5 3.0 2.0 2 0 0 2 2 1 0 MYND finger PDEase_I PF00233.14 KEP67612.1 - 6e-39 134.1 0.2 6.8e-38 130.7 0.0 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase EIAV_GP90 PF00971.13 KEP67612.1 - 1.3 7.4 0.1 2.2 6.6 0.1 1.3 1 0 0 1 1 1 0 EIAV coat protein, gp90 zf-C3HC4_2 PF13923.1 KEP67613.1 - 7e-07 29.1 12.8 1.3e-06 28.3 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEP67613.1 - 3.9e-06 26.4 10.9 7.4e-06 25.5 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEP67613.1 - 4.1e-06 26.5 11.4 7.6e-06 25.6 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEP67613.1 - 0.00082 18.9 14.5 0.0014 18.2 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEP67613.1 - 0.0015 18.2 10.9 0.0027 17.3 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEP67613.1 - 0.011 15.6 11.5 0.021 14.7 7.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEP67613.1 - 0.019 14.6 6.9 0.04 13.6 4.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 KEP67613.1 - 0.084 12.6 10.1 0.17 11.6 7.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KEP67613.1 - 0.099 12.1 7.7 0.22 11.0 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CDC45 PF02724.9 KEP67613.1 - 0.18 9.7 7.0 0.32 8.9 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-RING_4 PF14570.1 KEP67613.1 - 0.58 9.7 10.5 1.4 8.6 7.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KEP67613.1 - 0.8 9.8 5.3 1.5 8.9 3.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger ABC_tran PF00005.22 KEP67614.1 - 1.3e-38 132.3 0.0 4.6e-20 72.3 0.0 4.3 4 1 0 4 4 3 3 ABC transporter AAA_21 PF13304.1 KEP67614.1 - 6.6e-20 72.2 0.6 9.5e-05 22.4 0.0 4.5 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KEP67614.1 - 3.5e-10 39.4 0.0 0.1 11.8 0.0 3.7 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEP67614.1 - 5.7e-08 32.1 0.1 0.0025 17.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KEP67614.1 - 3.9e-07 30.9 1.7 0.001 19.8 0.1 3.4 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.1 KEP67614.1 - 6.9e-07 29.7 13.7 0.002 18.5 0.3 3.7 3 1 0 3 3 3 2 AAA domain MobB PF03205.9 KEP67614.1 - 5.5e-06 26.1 0.0 0.08 12.6 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KEP67614.1 - 6.2e-06 25.9 0.1 0.16 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 KEP67614.1 - 3.7e-05 22.9 0.0 0.98 8.3 0.0 3.4 4 0 0 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.1 KEP67614.1 - 3.8e-05 23.5 0.3 0.0037 17.1 0.0 3.6 2 2 1 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KEP67614.1 - 5.8e-05 23.2 0.2 0.14 12.3 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 KEP67614.1 - 6e-05 22.2 0.1 0.1 11.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 KEP67614.1 - 6.8e-05 22.5 2.1 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEP67614.1 - 8.4e-05 22.4 0.2 0.26 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KEP67614.1 - 8.6e-05 23.0 0.0 0.27 11.7 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 KEP67614.1 - 9e-05 21.9 0.1 0.057 12.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEP67614.1 - 0.00015 21.7 2.0 0.062 13.2 0.1 3.2 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 KEP67614.1 - 0.00018 21.4 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KEP67614.1 - 0.00018 21.0 0.9 0.034 13.5 0.1 3.1 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 KEP67614.1 - 0.00079 19.6 0.0 3.3 7.9 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KEP67614.1 - 0.00084 18.9 0.3 0.078 12.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KEP67614.1 - 0.00096 18.8 5.1 0.31 10.8 0.7 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_24 PF13479.1 KEP67614.1 - 0.00098 18.7 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEP67614.1 - 0.001 19.3 0.0 0.044 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEP67614.1 - 0.0013 17.8 0.7 0.64 9.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 KEP67614.1 - 0.0027 17.4 0.2 0.57 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEP67614.1 - 0.0028 17.1 0.1 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KEP67614.1 - 0.029 14.3 13.6 0.2 11.6 0.1 3.8 3 1 0 3 3 2 0 AAA ATPase domain cobW PF02492.14 KEP67614.1 - 0.031 13.7 0.1 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KEP67614.1 - 0.032 14.4 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.17 KEP67614.1 - 0.047 13.1 0.1 7.4 5.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 KEP67614.1 - 0.063 13.1 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.16 KEP67614.1 - 0.067 12.5 0.0 8.1 5.7 0.0 2.2 2 0 0 2 2 2 0 MutS domain V Pox_A32 PF04665.7 KEP67614.1 - 0.091 12.0 0.1 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 KEP67614.1 - 0.091 12.2 0.1 8.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KEP67614.1 - 0.12 11.8 6.3 0.88 9.0 0.0 3.0 4 0 0 4 4 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 KEP67614.1 - 0.14 11.6 0.0 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KEP67614.1 - 0.28 10.9 2.1 2.2 8.0 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 MCM PF00493.18 KEP67614.1 - 0.42 9.3 0.1 23 3.6 0.0 2.1 2 0 0 2 2 2 0 MCM2/3/5 family KAP_NTPase PF07693.9 KEP67614.1 - 0.51 9.2 0.2 5.8 5.7 0.0 2.3 3 0 0 3 3 3 0 KAP family P-loop domain Arch_ATPase PF01637.13 KEP67614.1 - 0.68 9.5 2.9 6.8 6.3 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase Dynamin_N PF00350.18 KEP67614.1 - 1.4 8.7 7.7 1.7 8.4 0.0 3.0 4 0 0 4 4 2 0 Dynamin family AAA_13 PF13166.1 KEP67614.1 - 2.3 6.5 6.3 3 6.1 0.0 3.1 4 0 0 4 4 4 0 AAA domain GSH_synth_ATP PF03917.12 KEP67615.1 - 7.8e-44 149.7 6.2 1.9e-10 39.9 0.0 6.4 7 0 0 7 7 7 6 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KEP67615.1 - 1.6e-16 60.2 0.6 4.4e-12 46.0 0.1 3.1 3 0 0 3 3 3 2 Eukaryotic glutathione synthase SET PF00856.23 KEP67616.1 - 4.2e-19 69.4 0.4 4.2e-19 69.4 0.2 4.1 2 1 0 2 2 2 1 SET domain Bromodomain PF00439.20 KEP67616.1 - 1.3e-13 50.6 0.0 2.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 KEP67616.1 - 0.00015 21.3 70.4 0.0005 19.6 2.5 8.0 7 0 0 7 7 7 4 PHD-finger FYRN PF05964.9 KEP67616.1 - 4.7 6.7 0.0 13 5.3 0.0 1.7 2 0 0 2 2 2 0 F/Y-rich N-terminus PPI_Ypi1 PF07491.6 KEP67618.1 - 3.3e-22 77.8 1.8 5.5e-22 77.1 1.3 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor MTBP_C PF14920.1 KEP67618.1 - 0.12 11.8 4.5 0.14 11.5 3.1 1.1 1 0 0 1 1 1 0 MDM2-binding HSP70 PF00012.15 KEP67619.1 - 9.3e-59 198.8 48.2 2.2e-49 167.9 0.1 4.3 3 1 0 4 4 4 3 Hsp70 protein MreB_Mbl PF06723.8 KEP67619.1 - 2.7e-06 26.2 0.1 5.4e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein SprA-related PF12118.3 KEP67620.1 - 5.2 6.3 33.2 5.8 6.1 23.0 1.1 1 0 0 1 1 1 0 SprA-related family DUF4045 PF13254.1 KEP67620.1 - 8 5.6 28.3 8.2 5.5 19.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Cupin_8 PF13621.1 KEP67621.1 - 8.1e-38 130.3 0.0 9.9e-37 126.7 0.0 2.5 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 KEP67621.1 - 0.00045 19.5 0.8 0.0086 15.3 0.0 2.6 3 0 0 3 3 3 1 Cupin superfamily protein Fmp27_WPPW PF10359.4 KEP67621.1 - 0.034 12.5 2.3 0.058 11.8 1.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain BTV_NS2 PF04514.7 KEP67621.1 - 0.8 8.5 3.6 1.7 7.4 2.5 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RabGAP-TBC PF00566.13 KEP67622.1 - 6e-51 172.9 0.0 8.6e-51 172.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1070 PF06376.7 KEP67623.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1070) SAG PF04092.8 KEP67623.1 - 0.021 15.2 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 SRS domain Tubulin PF00091.20 KEP67624.1 - 6.4e-76 254.9 0.0 9e-76 254.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEP67624.1 - 1.9e-46 157.1 0.7 1.9e-46 157.1 0.5 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEP67624.1 - 2.9e-07 30.5 0.0 5.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain ORC3_N PF07034.6 KEP67626.1 - 0.00025 20.1 1.5 0.00041 19.4 0.1 2.2 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus SSXT PF05030.7 KEP67627.1 - 6.1e-05 22.5 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) hDGE_amylase PF14701.1 KEP67628.1 - 2.1e-128 428.8 0.0 2.5e-103 346.2 0.0 2.1 2 0 0 2 2 2 2 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KEP67628.1 - 1.6e-107 359.4 0.0 2.5e-107 358.7 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KEP67628.1 - 2.6e-40 138.2 0.0 4.1e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme Alpha-amylase PF00128.19 KEP67628.1 - 0.28 10.5 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Trypsin_2 PF13365.1 KEP67629.1 - 1e-12 48.0 2.0 1.5e-11 44.3 1.0 3.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain RAP1 PF07218.6 KEP67629.1 - 9.2 4.2 9.1 19 3.1 6.3 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FUSC PF04632.7 KEP67630.1 - 0.25 9.7 1.8 0.29 9.5 1.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family UCH PF00443.24 KEP67632.1 - 1.7e-37 128.9 0.0 3.7e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEP67632.1 - 1.2e-13 51.2 0.0 2.8e-11 43.3 0.0 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nop14 PF04147.7 KEP67633.1 - 1.2 7.0 34.8 2.7 5.8 24.1 1.5 1 0 0 1 1 1 0 Nop14-like family DUF2151 PF10221.4 KEP67633.1 - 9.5 4.2 11.1 17 3.4 7.7 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator PFK PF00365.15 KEP67634.1 - 4.5e-28 98.0 4.8 4.1e-23 81.7 0.1 2.6 2 1 0 2 2 2 2 Phosphofructokinase Prefoldin_2 PF01920.15 KEP67635.1 - 0.0033 17.1 0.0 0.0038 16.9 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Ribosomal_S17 PF00366.15 KEP67636.1 - 1.6e-27 95.3 0.7 2.4e-27 94.7 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 eIF3_subunit PF08597.5 KEP67637.1 - 5e-17 62.2 16.2 6.3e-17 61.9 11.3 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit AATF-Che1 PF13339.1 KEP67637.1 - 5.3 7.2 9.5 0.28 11.3 0.8 2.4 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IncA PF04156.9 KEP67641.1 - 2.4 7.7 13.0 0.5 9.9 3.5 2.2 2 0 0 2 2 2 0 IncA protein TSC22 PF01166.13 KEP67642.1 - 0.6 10.1 15.3 1.2 9.1 0.0 5.5 5 2 1 6 6 6 0 TSC-22/dip/bun family SIR2 PF02146.12 KEP67644.1 - 4.3e-47 160.1 0.0 6.1e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KEP67644.1 - 3.6e-05 23.5 0.0 0.00084 19.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PHP_C PF13263.1 KEP67644.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 PHP-associated HATPase_c PF02518.21 KEP67646.1 - 6.3e-14 51.6 0.0 5e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_MLP1_2 PF07926.7 KEP67648.1 - 0.0058 16.3 9.1 0.014 15.1 6.3 1.8 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 KEP67648.1 - 0.028 13.1 8.7 0.041 12.5 6.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Coa1 PF08695.5 KEP67648.1 - 0.057 12.9 0.2 5 6.6 0.0 2.6 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 AAA_13 PF13166.1 KEP67648.1 - 0.081 11.3 6.9 0.13 10.7 4.8 1.3 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.11 KEP67648.1 - 0.53 8.8 2.2 0.55 8.7 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PEP-utilisers_N PF05524.8 KEP67648.1 - 0.63 9.8 9.3 0.68 9.7 5.0 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal V_ATPase_I PF01496.14 KEP67648.1 - 1.1 7.0 5.6 1.4 6.6 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KEP67648.1 - 1.3 8.6 12.0 2.7 7.6 8.3 1.5 1 0 0 1 1 1 0 Mnd1 family CALCOCO1 PF07888.6 KEP67648.1 - 1.4 7.1 17.1 0.59 8.3 10.2 1.5 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Atg14 PF10186.4 KEP67648.1 - 2.2 7.1 11.4 4 6.2 7.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KEP67648.1 - 2.6 7.5 14.2 5.1 6.6 9.9 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KEP67648.1 - 5.1 6.6 8.8 0.29 10.6 1.8 2.1 2 0 0 2 2 2 0 Septum formation initiator PCIF1_WW PF12237.3 KEP67649.1 - 9.2e-50 168.3 0.1 1.6e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain AA_kinase PF00696.23 KEP67650.1 - 2.3e-49 168.1 0.0 3.5e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 KEP67650.1 - 0.0014 18.0 1.1 0.15 11.5 0.0 3.2 3 0 0 3 3 3 2 ACT domain Peptidase_S49 PF01343.13 KEP67650.1 - 0.0034 17.1 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 Glutaredoxin PF00462.19 KEP67651.1 - 0.00072 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Glutaredoxin PF00462.19 KEP67654.1 - 4.2e-14 52.2 0.1 8.1e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KEP67654.1 - 0.0048 16.6 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Ecl1 PF12855.2 KEP67654.1 - 0.35 10.2 3.0 1.6 8.1 0.4 2.2 2 0 0 2 2 2 0 Life-span regulatory factor RIO1 PF01163.17 KEP67655.1 - 1.1e-44 152.0 0.2 1.1e-44 152.0 0.1 1.8 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 KEP67655.1 - 6e-33 112.7 3.2 4.2e-32 110.0 0.2 2.6 3 0 0 3 3 3 1 Rio2, N-terminal APH PF01636.18 KEP67655.1 - 1.2e-07 31.7 6.6 0.00014 21.7 0.5 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEP67655.1 - 8.2e-07 28.2 0.4 1.5e-05 24.1 0.2 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PRCC PF10253.4 KEP67656.1 - 3.4e-32 112.5 3.9 3.4e-32 112.5 2.7 2.3 4 0 0 4 4 4 1 Mitotic checkpoint regulator, MAD2B-interacting APC_CDC26 PF10471.4 KEP67656.1 - 0.14 12.9 0.4 0.14 12.9 0.3 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF2087 PF09860.4 KEP67657.1 - 0.01 15.5 1.8 0.015 15.0 0.4 1.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) Hist_deacetyl PF00850.14 KEP67658.1 - 2.9e-77 260.0 0.2 4e-77 259.5 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Dehydrin PF00257.14 KEP67662.1 - 0.0095 16.2 0.1 0.025 14.9 0.0 1.6 1 0 0 1 1 1 1 Dehydrin Macoilin PF09726.4 KEP67662.1 - 0.67 8.1 8.4 1.2 7.2 5.8 1.5 1 1 0 1 1 1 0 Transmembrane protein DUF723 PF05265.8 KEP67663.1 - 0.012 15.3 0.1 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF723) YbjM PF11045.3 KEP67664.1 - 0.021 14.5 0.9 0.026 14.2 0.6 1.1 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae DUF1324 PF07038.6 KEP67664.1 - 2.8 8.0 10.4 1.4 8.9 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) Patched PF02460.13 KEP67665.1 - 1.1e-10 40.2 19.2 6.6e-06 24.3 3.8 3.6 3 1 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 KEP67665.1 - 9.5e-07 28.3 11.8 2.6e-06 26.9 2.4 2.8 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ALAD PF00490.16 KEP67665.1 - 0.32 9.8 0.0 0.54 9.0 0.0 1.2 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Ribosomal_L3 PF00297.17 KEP67666.1 - 9.2e-111 369.4 4.5 1.1e-110 369.1 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3903 PF13043.1 KEP67666.1 - 0.68 9.4 0.1 0.68 9.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3903) Peptidase_S15 PF02129.13 KEP67667.1 - 1e-45 156.2 0.7 2.5e-44 151.7 0.2 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KEP67667.1 - 3.2e-12 46.8 0.0 1.3e-09 38.3 0.0 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 KEP67667.1 - 7.2e-07 29.0 0.2 0.00083 19.1 0.1 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP67667.1 - 2.5e-06 27.5 0.7 5.6e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEP67667.1 - 0.0034 16.6 2.4 0.0076 15.4 1.7 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KEP67667.1 - 0.007 16.1 0.1 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Sugarporin_N PF11471.3 KEP67667.1 - 0.047 13.3 1.3 0.12 12.0 0.9 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension SET PF00856.23 KEP67669.1 - 0.028 14.7 0.0 9.8 6.4 0.0 2.7 2 0 0 2 2 2 0 SET domain TYW3 PF02676.9 KEP67670.1 - 2e-22 79.3 5.9 1.2e-13 50.6 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase TYW3 LYTB PF02401.13 KEP67672.1 - 1.8e-103 345.3 0.8 2.7e-103 344.7 0.6 1.2 1 0 0 1 1 1 1 LytB protein Aa_trans PF01490.13 KEP67673.1 - 5.8e-48 163.3 25.1 6.9e-48 163.1 17.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein WD40 PF00400.27 KEP67674.1 - 3.9e-16 58.2 15.9 4.5e-05 23.1 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat DCP2 PF05026.8 KEP67675.1 - 2.1e-22 78.8 1.1 3.6e-22 78.0 0.8 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KEP67675.1 - 9.2e-12 44.7 0.1 1.9e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Med26 PF08711.6 KEP67676.1 - 1.6e-07 30.6 0.1 2.9e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RNA_polI_A34 PF08208.6 KEP67676.1 - 0.3 10.7 16.9 0.64 9.6 11.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NARP1 PF12569.3 KEP67676.1 - 0.59 8.8 9.0 1.2 7.7 6.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNase_H2-Ydr279 PF09468.5 KEP67676.1 - 0.81 8.8 7.3 2.9 7.0 5.3 1.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) BLVR PF06375.6 KEP67676.1 - 1.7 8.4 17.6 5.2 6.8 12.2 1.8 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) TFIIF_alpha PF05793.7 KEP67676.1 - 5.2 5.3 28.4 8.3 4.6 19.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aa_trans PF01490.13 KEP67677.1 - 6e-55 186.3 27.1 7.6e-55 186.0 18.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 KEP67678.1 - 1.6e-51 175.0 31.7 1.9e-51 174.8 22.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L34e PF01199.13 KEP67680.1 - 1e-34 118.6 4.6 1e-34 118.6 3.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 KEP67680.1 - 0.054 13.1 3.2 0.19 11.3 2.2 2.0 1 1 0 1 1 1 0 Cytochrome c7 Cytochrome_C554 PF13435.1 KEP67680.1 - 0.81 9.7 7.0 1.8 8.6 4.9 1.5 1 1 0 1 1 1 0 Cytochrome c554 and c-prime EndIII_4Fe-2S PF10576.4 KEP67680.1 - 5.7 7.2 7.4 2.1 8.6 0.7 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III TRAPPC10 PF12584.3 KEP67681.1 - 1.7e-06 27.5 0.1 8.2e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun PF07919.7 KEP67681.1 - 0.0011 17.3 0.0 0.0016 16.8 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi TPR_2 PF07719.12 KEP67681.1 - 0.0085 15.9 0.6 2 8.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 KEP67681.1 - 0.048 13.1 0.2 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Foie gras liver health family 1 SNAP PF14938.1 KEP67681.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 KEP67681.1 - 0.22 11.8 0.3 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Gryzun-like PF12742.2 KEP67681.1 - 1.7 8.4 0.0 3.2 7.6 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Copper-fist PF00649.13 KEP67683.1 - 0.15 11.2 0.5 0.23 10.7 0.3 1.3 1 0 0 1 1 1 0 Copper fist DNA binding domain EB1 PF03271.12 KEP67684.1 - 1e-07 31.8 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif PspB PF06667.7 KEP67684.1 - 0.026 14.4 0.2 0.053 13.4 0.2 1.5 1 0 0 1 1 1 0 Phage shock protein B DUF566 PF04484.7 KEP67684.1 - 0.63 9.4 5.5 1 8.7 3.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DNA_methylase PF00145.12 KEP67685.1 - 4.1e-24 85.3 0.0 1.1e-14 54.3 0.0 3.2 3 0 0 3 3 3 3 C-5 cytosine-specific DNA methylase E1-E2_ATPase PF00122.15 KEP67686.1 - 0.0005 19.1 0.1 0.0019 17.2 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Glycos_transf_1 PF00534.15 KEP67687.1 - 4e-24 84.9 0.0 1.4e-23 83.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KEP67687.1 - 9.8e-07 28.9 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEP67687.1 - 1.2e-06 28.7 0.0 5.8e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 EF-hand_4 PF12763.2 KEP67688.1 - 3.3e-21 74.9 0.0 4.7e-11 42.3 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KEP67688.1 - 8.3e-09 35.4 0.1 1.4e-06 28.3 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KEP67688.1 - 1.1e-08 33.7 0.0 0.0016 17.6 0.0 3.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEP67688.1 - 0.00016 21.2 0.1 0.48 10.4 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 KEP67688.1 - 0.016 14.8 0.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 KEP67688.1 - 0.61 9.5 2.6 1.3 8.4 0.0 3.0 4 0 0 4 4 4 0 EF hand Kinase-like PF14531.1 KEP67689.1 - 1.7e-11 43.6 0.0 3.6e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KEP67689.1 - 6.4e-09 35.3 0.0 6.7e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DUF2450 PF10475.4 KEP67690.1 - 0.00069 18.5 5.9 0.0024 16.8 3.4 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec20 PF03908.8 KEP67690.1 - 0.031 13.9 0.2 0.087 12.5 0.1 1.7 1 0 0 1 1 1 0 Sec20 COG2 PF06148.6 KEP67690.1 - 1.2 9.0 5.7 4.3 7.2 3.9 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Tim44 PF04280.10 KEP67693.1 - 1.4e-18 67.2 0.0 1.9e-17 63.6 0.0 2.5 1 1 0 1 1 1 1 Tim44-like domain DMPK_coil PF08826.5 KEP67693.1 - 0.042 13.7 4.1 0.058 13.2 0.1 3.0 2 2 1 3 3 3 0 DMPK coiled coil domain like PRT_C PF08372.5 KEP67693.1 - 0.084 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Memo PF01875.12 KEP67694.1 - 5.5e-74 248.5 0.0 6.3e-74 248.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Pro_isomerase PF00160.16 KEP67695.1 - 2.2e-23 83.1 0.0 5.3e-11 42.9 0.0 2.4 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KEP67695.1 - 6.6e-14 51.3 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEP67695.1 - 1e-09 38.1 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEP67695.1 - 3.9e-05 23.4 0.0 6.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRP-S25 PF13741.1 KEP67696.1 - 0.0022 17.5 1.2 0.19 11.1 0.4 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 DUF1635 PF07795.6 KEP67696.1 - 0.077 12.3 0.9 0.12 11.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) zf-Tim10_DDP PF02953.10 KEP67697.1 - 2.2e-11 42.8 2.6 3e-11 42.4 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cupin_2 PF07883.6 KEP67698.1 - 0.00091 18.6 0.0 0.0028 17.1 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Herpes_capsid PF06112.6 KEP67699.1 - 8.3 6.4 11.2 0.94 9.5 0.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Pollen_Ole_e_I PF01190.12 KEP67700.1 - 0.094 12.5 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Pollen proteins Ole e I like DUF1875 PF08961.5 KEP67701.1 - 0.29 10.4 7.4 0.55 9.5 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) 14-3-3 PF00244.15 KEP67705.1 - 8.7e-24 83.9 1.8 1.1e-23 83.5 1.2 1.1 1 0 0 1 1 1 1 14-3-3 protein FixO PF02433.10 KEP67705.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO TPR_12 PF13424.1 KEP67705.1 - 0.22 11.4 1.7 5.6 6.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PCI PF01399.22 KEP67706.1 - 1.2e-17 64.0 1.2 3e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 KEP67706.1 - 0.016 15.5 0.7 0.016 15.5 0.5 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEP67706.1 - 0.042 14.5 0.4 0.042 14.5 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEP67706.1 - 0.053 13.4 0.2 0.053 13.4 0.1 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 KEP67706.1 - 0.062 13.4 1.6 0.21 11.7 0.1 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KEP67706.1 - 0.068 13.1 6.1 1.9 8.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEP67706.1 - 0.09 12.6 0.9 9.3 6.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEP67706.1 - 0.27 11.9 0.1 0.27 11.9 0.1 4.9 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEP67706.1 - 0.28 11.0 0.1 0.28 11.0 0.1 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEP67706.1 - 0.84 10.2 7.4 2.3 8.8 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Bac_DNA_binding PF00216.16 KEP67707.1 - 3.6e-24 84.5 0.1 6.3e-24 83.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial DNA-binding protein DUF4496 PF14908.1 KEP67707.1 - 0.00024 21.0 0.1 0.062 13.1 0.0 1.7 1 1 1 2 2 2 2 Domain of unknown function (DUF4496) PqqD PF05402.7 KEP67707.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) CDK2AP PF09806.4 KEP67708.1 - 0.05 13.8 1.6 0.15 12.2 1.1 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Mcm10 PF09332.6 KEP67709.1 - 2.8 7.1 8.3 6.6 5.9 5.7 1.5 1 0 0 1 1 1 0 Mcm10 replication factor zf-met PF12874.2 KEP67710.1 - 5.8e-05 23.1 0.5 0.00012 22.2 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 KEP67710.1 - 0.0022 17.5 0.8 0.003 17.1 0.1 1.5 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Lipoprotein_18 PF06804.6 KEP67710.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 NlpB/DapX lipoprotein MitMem_reg PF13012.1 KEP67711.1 - 2.9e-06 27.3 0.0 4.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF566 PF04484.7 KEP67711.1 - 0.38 10.2 13.5 0.65 9.4 9.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 KEP67711.1 - 0.65 8.2 4.8 0.85 7.8 3.4 1.2 1 0 0 1 1 1 0 Transmembrane protein TPT PF03151.11 KEP67712.1 - 1.3e-05 24.8 0.0 4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Triose-phosphate Transporter family FHA PF00498.21 KEP67713.1 - 1.8e-16 59.9 0.0 3.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Rotamase PF00639.16 KEP67713.1 - 4.9e-12 46.4 0.0 4.9e-12 46.4 0.0 2.5 2 2 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KEP67713.1 - 6e-08 32.9 0.0 2.7e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KEP67713.1 - 0.011 16.2 0.0 0.011 16.2 0.0 3.2 3 1 0 3 3 3 0 PPIC-type PPIASE domain CRA PF06589.6 KEP67714.1 - 0.14 11.4 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF4265 PF14085.1 KEP67715.1 - 0.11 12.2 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) B-block_TFIIIC PF04182.7 KEP67717.1 - 1.1e-11 44.3 0.0 8.3e-11 41.5 0.0 2.3 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.7 KEP67717.1 - 0.38 9.8 0.0 0.66 9.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Dus PF01207.12 KEP67718.1 - 4.9e-49 166.8 0.0 7.9e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) WD40 PF00400.27 KEP67719.1 - 0.016 15.1 11.7 5.8 6.9 0.0 6.6 6 0 0 6 6 6 0 WD domain, G-beta repeat Zip PF02535.17 KEP67719.1 - 0.041 12.8 0.0 0.089 11.7 0.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Tmemb_14 PF03647.8 KEP67720.1 - 9.4e-07 29.1 10.7 1.2e-06 28.8 7.4 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C FecCD PF01032.13 KEP67720.1 - 0.15 10.8 6.4 0.19 10.5 4.4 1.1 1 0 0 1 1 1 0 FecCD transport family DNMT1-RFD PF12047.3 KEP67721.1 - 5e-08 32.7 0.2 5e-08 32.7 0.1 2.8 3 0 0 3 3 3 1 Cytosine specific DNA methyltransferase replication foci domain Auxin_resp PF06507.8 KEP67721.1 - 8.9e-06 25.4 0.1 3.7e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 Auxin response factor DDT PF02791.12 KEP67721.1 - 0.28 10.9 0.1 0.53 10.0 0.1 1.4 1 0 0 1 1 1 0 DDT domain START PF01852.14 KEP67722.1 - 3.4e-06 26.5 0.2 9.9e-06 25.0 0.1 1.7 2 0 0 2 2 2 1 START domain Metallophos PF00149.23 KEP67726.1 - 2.9e-07 30.0 1.2 5.7e-07 29.1 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 KEP67727.1 - 3.6e-07 29.7 0.2 6.9e-07 28.8 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CesA PF11439.3 KEP67727.1 - 0.0075 16.1 0.1 3.2 7.7 0.0 3.1 2 0 0 2 2 2 2 Type III secretion system filament chaperone CesA COX15-CtaA PF02628.10 KEP67729.1 - 5.3e-65 219.2 10.7 6e-65 219.0 7.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein JAB PF01398.16 KEP67730.1 - 2.7e-13 49.6 0.1 9.9e-13 47.8 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KEP67730.1 - 2.4e-09 37.2 0.0 4.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Chorion_2 PF03964.10 KEP67730.1 - 0.031 14.8 0.4 0.055 14.0 0.3 1.4 1 0 0 1 1 1 0 Chorion family 2 V-ATPase_G PF03179.10 KEP67731.1 - 5.9e-08 32.9 5.7 1.3e-07 31.8 4.0 1.6 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KEP67731.1 - 0.0024 17.6 9.6 0.0051 16.6 6.7 1.4 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) HrpE PF06188.7 KEP67731.1 - 0.0094 15.7 4.2 0.016 14.9 2.9 1.3 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E DUF3552 PF12072.3 KEP67731.1 - 0.096 11.8 11.0 0.16 11.1 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RapA_C PF12137.3 KEP67731.1 - 0.25 10.1 5.2 0.38 9.5 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal AAA PF00004.24 KEP67732.1 - 2.9e-42 143.9 0.0 5.5e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KEP67732.1 - 2.4e-07 30.8 0.0 8.8e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEP67732.1 - 5.6e-07 29.3 0.0 2.8e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEP67732.1 - 2.7e-06 27.4 0.0 8.6e-05 22.5 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 KEP67732.1 - 4.4e-06 26.8 0.0 0.00095 19.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEP67732.1 - 6.8e-06 25.2 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KEP67732.1 - 0.0005 19.5 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 KEP67732.1 - 0.00076 20.2 0.0 0.0024 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEP67732.1 - 0.0011 17.7 0.6 0.0022 16.7 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 KEP67732.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEP67732.1 - 0.002 17.2 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF4200 PF13863.1 KEP67732.1 - 0.0025 17.7 3.4 0.0052 16.7 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) RNA_helicase PF00910.17 KEP67732.1 - 0.0026 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 KEP67732.1 - 0.0027 16.8 0.0 0.0065 15.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KEP67732.1 - 0.0043 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 KEP67732.1 - 0.0045 16.4 0.1 0.014 14.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.8 KEP67732.1 - 0.0048 15.8 0.0 0.011 14.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 KEP67732.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KEP67732.1 - 0.0068 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEP67732.1 - 0.007 16.6 0.0 0.031 14.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain PhoH PF02562.11 KEP67732.1 - 0.0079 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.1 KEP67732.1 - 0.01 15.2 0.2 0.069 12.5 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEP67732.1 - 0.011 15.6 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KEP67732.1 - 0.013 15.4 0.0 0.06 13.3 0.0 2.1 3 0 0 3 3 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 KEP67732.1 - 0.014 14.9 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KEP67732.1 - 0.019 13.8 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 KEP67732.1 - 0.024 13.7 0.0 0.069 12.2 0.0 1.8 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 KEP67732.1 - 0.03 14.0 0.2 0.17 11.5 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 KEP67732.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KEP67732.1 - 0.033 13.8 0.1 0.21 11.2 0.0 2.2 1 1 2 3 3 3 0 NACHT domain Med4 PF10018.4 KEP67732.1 - 0.034 13.5 0.3 0.078 12.3 0.2 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Phage_GP20 PF06810.6 KEP67732.1 - 0.04 13.3 1.8 0.64 9.4 1.0 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 AAA_11 PF13086.1 KEP67732.1 - 0.053 13.0 0.3 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 KEP67732.1 - 0.2 11.2 1.6 0.37 10.3 1.1 1.4 1 0 0 1 1 1 0 IncA protein zf-MYND PF01753.13 KEP67733.1 - 6.1e-11 42.0 17.9 6.1e-11 42.0 12.4 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KEP67733.1 - 1.1 9.1 12.4 0.28 11.0 5.5 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 GTP_EFTU PF00009.22 KEP67736.1 - 4.3e-29 101.2 0.0 1.2e-28 99.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEP67736.1 - 9.2e-11 41.5 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 KEP67736.1 - 3.8e-07 30.0 0.0 7.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEP67736.1 - 4.3e-05 23.9 0.0 0.00011 22.6 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KEP67736.1 - 0.00033 20.5 3.2 0.0012 18.7 0.0 2.9 2 1 1 3 3 3 1 Dynamin family DLIC PF05783.6 KEP67736.1 - 0.0089 14.7 0.2 0.022 13.4 0.1 1.6 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) cobW PF02492.14 KEP67736.1 - 0.024 14.1 0.1 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 KEP67736.1 - 0.072 12.3 0.1 1.3 8.1 0.1 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KEP67736.1 - 0.089 12.0 0.1 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KEP67736.1 - 0.096 12.1 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 KEP67736.1 - 0.099 12.0 0.2 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Ras family ABC_tran PF00005.22 KEP67736.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Arf PF00025.16 KEP67736.1 - 0.17 11.1 0.0 7 5.8 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family KBP_C PF12309.3 KEP67736.1 - 0.54 9.1 5.6 1 8.2 3.9 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal RR_TM4-6 PF06459.7 KEP67737.1 - 5 6.9 12.8 7.4 6.3 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Abhydrolase_2 PF02230.11 KEP67739.1 - 1.1e-39 136.1 0.0 3.6e-32 111.5 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KEP67739.1 - 1.5e-11 44.2 0.0 2.6e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEP67739.1 - 5.2e-11 42.8 0.0 1.4e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DDHD PF02862.12 KEP67739.1 - 0.0048 16.7 0.9 0.0096 15.7 0.6 1.5 1 0 0 1 1 1 1 DDHD domain Abhydrolase_3 PF07859.8 KEP67739.1 - 0.0048 16.4 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tim54 PF11711.3 KEP67739.1 - 0.013 14.1 3.5 0.019 13.5 2.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S9 PF00326.16 KEP67739.1 - 0.021 14.0 2.8 0.13 11.4 0.2 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_U57 PF05582.7 KEP67739.1 - 0.15 10.9 3.5 0.22 10.4 2.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF1510 PF07423.6 KEP67739.1 - 0.71 9.2 13.8 1.1 8.5 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KEP67739.1 - 0.84 7.2 5.9 1.1 6.9 4.1 1.0 1 0 0 1 1 1 0 Ycf1 FSH1 PF03959.8 KEP67739.1 - 0.89 8.9 4.4 33 3.8 3.8 2.7 2 1 0 2 2 2 0 Serine hydrolase (FSH1) RNase_H2-Ydr279 PF09468.5 KEP67739.1 - 1.1 8.3 8.6 2 7.5 6.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) YqfQ PF14181.1 KEP67739.1 - 1.3 9.0 14.3 2.2 8.3 9.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein NARP1 PF12569.3 KEP67739.1 - 1.5 7.4 11.0 2.2 6.9 7.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM176 PF14851.1 KEP67739.1 - 2.3 7.8 6.7 4.8 6.8 4.6 1.5 1 0 0 1 1 1 0 FAM176 family Sec62 PF03839.11 KEP67739.1 - 8.5 5.7 11.7 13 5.1 8.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.7 KEP67739.1 - 10 5.9 12.5 17 5.2 8.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF814 PF05670.8 KEP67740.1 - 1.5e-20 72.8 0.0 3.9e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF814) SIT PF15330.1 KEP67740.1 - 0.087 12.9 1.2 0.16 12.1 0.8 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT INSIG PF07281.7 KEP67741.1 - 0.026 13.8 1.0 0.033 13.5 0.7 1.1 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) 7tm_7 PF08395.7 KEP67741.1 - 0.052 12.5 0.0 0.052 12.5 0.0 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor 5TM-5TMR_LYT PF07694.7 KEP67741.1 - 0.056 12.7 0.3 0.078 12.3 0.2 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DctQ PF04290.7 KEP67741.1 - 0.33 10.6 5.4 0.44 10.3 3.8 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Gaa1 PF04114.9 KEP67741.1 - 0.41 9.2 2.9 0.51 8.9 2.0 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component RBFA PF02033.13 KEP67742.1 - 1.7e-11 44.0 0.0 3.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A LHH PF14411.1 KEP67742.1 - 0.037 14.2 0.2 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH DUF3134 PF11332.3 KEP67742.1 - 0.041 14.0 0.2 0.097 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Trypan_PARP PF05887.6 KEP67743.1 - 0.58 9.9 5.4 0.8 9.5 3.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.4 KEP67743.1 - 1.2 7.5 20.4 1.4 7.2 14.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NIF PF03031.13 KEP67744.1 - 3.8e-15 55.8 0.1 3.4e-12 46.2 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KEP67744.1 - 0.00054 19.7 0.1 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain HAD_2 PF13419.1 KEP67744.1 - 0.16 12.1 1.2 0.61 10.2 0.0 2.6 4 0 0 4 4 4 0 Haloacid dehalogenase-like hydrolase GTP_EFTU PF00009.22 KEP67746.1 - 9.9e-25 87.0 0.0 3.6e-24 85.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEP67746.1 - 5.4e-09 35.8 0.1 0.0032 17.3 0.0 2.4 2 0 0 2 2 2 2 Translation-initiation factor 2 MMR_HSR1 PF01926.18 KEP67746.1 - 0.00013 21.9 0.0 0.00056 19.8 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEP67746.1 - 0.0062 15.7 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Miro PF08477.8 KEP67746.1 - 0.016 15.7 0.1 2.1 8.8 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein AAA_23 PF13476.1 KEP67746.1 - 0.29 11.4 2.4 22 5.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain CAF-1_p150 PF11600.3 KEP67747.1 - 0.67 9.2 23.6 0.83 8.9 16.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FKBP_C PF00254.23 KEP67748.1 - 2.4e-22 78.7 0.0 4.2e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase S1-P1_nuclease PF02265.11 KEP67749.1 - 3.2e-25 89.2 0.0 2.3e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 S1/P1 Nuclease RICTOR_M PF14666.1 KEP67751.1 - 7.7e-05 21.8 0.0 0.00025 20.1 0.0 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 KEP67751.1 - 0.00024 20.9 0.1 0.93 9.4 0.0 2.7 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, domain 5 PX PF00787.19 KEP67752.1 - 2.2e-14 53.1 0.0 4.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 PX domain WD40 PF00400.27 KEP67752.1 - 2.2e-08 33.6 0.1 0.13 12.1 0.1 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_N PF14781.1 KEP67752.1 - 0.009 15.6 0.0 4.8 6.8 0.0 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal COX5B PF01215.14 KEP67752.1 - 0.044 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb TTL PF03133.10 KEP67753.1 - 8.1e-78 261.3 2.8 1.5e-55 188.1 0.1 2.7 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 KEP67753.1 - 1.5e-05 23.9 0.0 0.0009 18.1 0.0 2.6 2 0 0 2 2 2 1 YheC/D like ATP-grasp Tetraspannin PF00335.15 KEP67753.1 - 0.0065 15.7 0.3 2 7.6 0.1 2.3 2 0 0 2 2 2 2 Tetraspanin family ATPgrasp_ST PF14397.1 KEP67753.1 - 0.074 12.1 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Pkinase PF00069.20 KEP67754.1 - 7.5e-63 212.0 0.0 8.6e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67754.1 - 1.2e-33 116.2 0.0 1.8e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEP67754.1 - 6.6e-09 35.1 0.0 9.6e-09 34.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEP67754.1 - 0.032 13.9 0.0 0.096 12.4 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEP67754.1 - 0.036 13.4 0.0 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KEP67754.1 - 0.062 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HTH_40 PF14493.1 KEP67756.1 - 0.12 12.5 0.0 2.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_L15e PF00827.12 KEP67758.1 - 2.9e-95 317.2 11.2 3.3e-95 317.0 7.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 BCIP PF13862.1 KEP67759.1 - 4.1e-43 147.1 0.0 5.9e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PDEase_I PF00233.14 KEP67760.1 - 8.6e-51 172.9 0.0 9.9e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HATPase_c PF02518.21 KEP67761.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PBP PF01161.15 KEP67762.1 - 1.7e-12 47.4 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Sec7 PF01369.15 KEP67764.1 - 1.2e-56 191.4 0.0 3.2e-56 190.0 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KEP67764.1 - 6.4e-18 64.7 7.5 3e-17 62.5 0.2 4.3 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KEP67764.1 - 3.1e-17 61.8 0.5 9.4e-17 60.3 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) DUF1539 PF07560.6 KEP67764.1 - 0.35 10.7 0.1 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF3149 PF11346.3 KEP67764.1 - 0.87 9.1 0.6 1.8 8.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) zf-H2C2_2 PF13465.1 KEP67765.1 - 0.4 11.0 3.9 9 6.7 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Mito_carr PF00153.22 KEP67766.1 - 6.5e-47 157.1 5.1 8e-16 57.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PI3_PI4_kinase PF00454.22 KEP67767.1 - 2.2e-34 118.9 0.0 1.2e-33 116.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CENP-B_dimeris PF09026.5 KEP67767.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Lactamase_B PF00753.22 KEP67769.1 - 0.093 12.3 0.0 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEP67769.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain UPF0086 PF01868.11 KEP67770.1 - 6.6e-13 48.1 0.1 1.1e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 EamA PF00892.15 KEP67771.1 - 0.03 14.3 8.1 0.031 14.3 0.2 2.6 2 0 0 2 2 2 0 EamA-like transporter family Pkinase PF00069.20 KEP67772.1 - 2.1e-72 243.3 0.0 3.2e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEP67772.1 - 1.4e-35 122.6 0.0 2.1e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 KEP67772.1 - 1.7e-12 47.4 0.0 2.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.27 KEP67772.1 - 4.6e-11 41.1 0.4 0.00043 19.3 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 KEP67772.1 - 3e-09 35.8 0.7 0.0023 17.1 0.0 3.4 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.1 KEP67772.1 - 3.2e-08 32.9 0.0 4.7e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like EF-hand_6 PF13405.1 KEP67772.1 - 5.9e-08 31.9 0.3 0.0045 16.7 0.0 3.0 3 0 0 3 3 2 2 EF-hand domain EF-hand_8 PF13833.1 KEP67772.1 - 4.2e-07 29.4 1.7 0.031 13.8 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 KEP67772.1 - 3.5e-06 27.0 1.1 3.5e-05 23.8 0.1 3.0 2 1 0 2 2 2 1 EF-hand domain pair Kdo PF06293.9 KEP67772.1 - 0.0018 17.4 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 KEP67772.1 - 0.0026 17.9 0.2 0.0062 16.7 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RIO1 PF01163.17 KEP67772.1 - 0.0089 15.3 0.2 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family PH_8 PF15409.1 KEP67772.1 - 0.065 13.3 0.1 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Pox_ser-thr_kin PF05445.6 KEP67772.1 - 0.065 12.0 0.1 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KEP67772.1 - 0.44 9.8 0.0 0.78 9.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cid2 PF09774.4 KEP67772.1 - 1.3 9.1 2.2 2.4 8.2 1.5 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 IFT20 PF14931.1 KEP67774.1 - 0.11 12.4 6.6 0.29 11.0 1.2 2.7 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20