# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Suf PF05843.9 CDJ61976.1 - 0.024 14.3 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Kri1_C PF12936.2 CDJ61977.1 - 2.1e-26 91.6 1.1 2.1e-26 91.6 0.7 5.6 5 1 1 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 CDJ61977.1 - 4.3e-10 39.7 31.4 4.3e-10 39.7 21.8 5.6 3 2 0 3 3 3 1 KRI1-like family ZZ PF00569.12 CDJ61977.1 - 4.4e-07 29.3 3.0 1.5e-06 27.6 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type Nop25 PF09805.4 CDJ61977.1 - 0.011 15.8 9.5 0.011 15.8 6.6 5.6 5 1 0 5 5 5 0 Nucleolar protein 12 (25kDa) TMEM51 PF15345.1 CDJ61978.1 - 0.00086 19.0 12.9 0.0011 18.7 8.9 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 Pex16 PF08610.5 CDJ61978.1 - 0.03 13.3 9.5 0.031 13.2 6.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PLRV_ORF5 PF01690.12 CDJ61978.1 - 0.036 13.2 12.9 0.037 13.1 8.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mitofilin PF09731.4 CDJ61978.1 - 0.04 12.5 17.7 0.044 12.4 12.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mem_trans PF03547.13 CDJ61978.1 - 0.044 12.0 8.6 0.048 11.9 6.0 1.2 1 0 0 1 1 1 0 Membrane transport protein CDK5_activator PF03261.10 CDJ61978.1 - 0.05 12.9 15.1 0.055 12.8 10.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF572 PF04502.8 CDJ61978.1 - 0.081 12.1 14.1 0.089 11.9 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAPS PF04499.10 CDJ61978.1 - 0.084 11.4 9.7 0.083 11.5 6.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF966 PF06136.8 CDJ61978.1 - 0.087 12.2 18.3 0.1 12.0 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Plasmodium_Vir PF05795.6 CDJ61978.1 - 0.096 11.8 13.5 0.12 11.5 9.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4175 PF13779.1 CDJ61978.1 - 0.098 10.3 29.9 0.12 9.9 20.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SSP160 PF06933.6 CDJ61978.1 - 0.1 10.5 19.3 0.17 9.8 13.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3373 PF11853.3 CDJ61978.1 - 0.13 10.7 5.2 0.14 10.6 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Hist_deacetyl PF00850.14 CDJ61978.1 - 0.14 11.4 7.0 0.15 11.3 4.9 1.1 1 0 0 1 1 1 0 Histone deacetylase domain Draxin PF15550.1 CDJ61978.1 - 0.14 11.7 12.0 0.18 11.3 8.3 1.1 1 0 0 1 1 1 0 Draxin Mcm10 PF09332.6 CDJ61978.1 - 0.35 10.1 17.8 0.4 9.9 12.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor SRP-alpha_N PF04086.8 CDJ61978.1 - 0.37 10.1 15.3 0.39 10.0 10.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Bud13 PF09736.4 CDJ61978.1 - 0.43 10.8 16.8 0.54 10.5 11.6 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DDRGK PF09756.4 CDJ61978.1 - 0.47 9.8 14.5 0.59 9.5 10.1 1.1 1 0 0 1 1 1 0 DDRGK domain SAGA-Tad1 PF12767.2 CDJ61978.1 - 0.6 9.7 17.1 0.73 9.4 11.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NABP PF07990.7 CDJ61978.1 - 0.64 9.2 17.9 0.71 9.0 12.4 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP HlyD_2 PF12700.2 CDJ61978.1 - 0.65 9.0 10.7 0.72 8.9 7.4 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Macoilin PF09726.4 CDJ61978.1 - 0.7 8.1 22.7 0.72 8.0 15.8 1.0 1 0 0 1 1 1 0 Transmembrane protein SelP_N PF04592.9 CDJ61978.1 - 0.8 9.0 21.8 1.1 8.6 15.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Late_protein_L2 PF00513.13 CDJ61978.1 - 0.82 8.4 12.2 0.9 8.3 8.5 1.0 1 0 0 1 1 1 0 Late Protein L2 LMBR1 PF04791.11 CDJ61978.1 - 1.1 7.8 7.5 1.2 7.6 5.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Otopetrin PF03189.8 CDJ61978.1 - 1.3 7.9 9.1 1.4 7.8 6.3 1.1 1 0 0 1 1 1 0 Otopetrin Neur_chan_memb PF02932.11 CDJ61978.1 - 1.4 8.7 11.9 1.5 8.6 8.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF566 PF04484.7 CDJ61978.1 - 1.7 8.0 21.7 2.2 7.7 15.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DNA_pol_viral_N PF00242.12 CDJ61978.1 - 1.7 7.5 25.9 2.1 7.2 17.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Spc7_N PF15402.1 CDJ61978.1 - 2 6.3 24.8 2.5 6.0 17.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4647 PF15504.1 CDJ61978.1 - 2.6 6.8 19.5 3.2 6.5 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) FimP PF09766.4 CDJ61978.1 - 2.6 7.0 24.3 3.5 6.6 16.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein FLO_LFY PF01698.11 CDJ61978.1 - 2.6 6.7 11.6 3 6.6 8.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein NST1 PF13945.1 CDJ61978.1 - 3 7.8 26.2 4.1 7.4 18.2 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2146 PF10220.4 CDJ61978.1 - 3.2 5.6 14.6 3.4 5.5 10.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) UPF0560 PF10577.4 CDJ61978.1 - 3.5 5.7 25.8 3.9 5.6 17.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.2 CDJ61978.1 - 3.6 5.1 25.5 4.4 4.8 17.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDJ61978.1 - 3.6 5.7 32.5 4.1 5.5 22.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAP1 PF08601.5 CDJ61978.1 - 3.6 7.1 24.2 3.8 7.0 16.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4045 PF13254.1 CDJ61978.1 - 3.8 6.6 23.2 4.8 6.3 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2052 PF09747.4 CDJ61978.1 - 4 7.3 18.7 5.1 6.9 13.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Cellulose_synt PF03552.9 CDJ61978.1 - 4.3 5.5 6.6 4.4 5.4 4.6 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF1635 PF07795.6 CDJ61978.1 - 5.1 6.4 18.1 8.1 5.7 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Pal1 PF08316.6 CDJ61978.1 - 5.9 7.3 15.6 9 6.7 10.8 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein MMR1 PF08505.5 CDJ61978.1 - 9.2 6.2 31.1 12 5.8 21.5 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF106 PF01956.11 CDJ61978.1 - 9.7 5.6 7.8 12 5.4 5.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 eIF-3_zeta PF05091.7 CDJ61978.1 - 9.9 4.6 18.3 12 4.4 12.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EF1_GNE PF00736.14 CDJ61979.1 - 1.1e-29 101.9 3.4 1.1e-29 101.9 2.4 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain Spt20 PF12090.3 CDJ61979.1 - 0.019 14.3 1.3 0.021 14.1 0.9 1.2 1 0 0 1 1 1 0 Spt20 family Phage_Mu_Gam PF07352.7 CDJ61979.1 - 0.036 13.6 10.1 0.053 13.0 7.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Flavin_Reduct PF01613.13 CDJ61979.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 Flavin reductase like domain RE_ApaLI PF09499.5 CDJ61979.1 - 0.15 11.4 2.4 0.073 12.4 0.3 1.4 2 0 0 2 2 2 0 ApaLI-like restriction endonuclease LcrG PF07216.7 CDJ61979.1 - 0.16 12.0 3.5 0.11 12.5 0.8 1.9 2 0 0 2 2 2 0 LcrG protein DUF4011 PF13195.1 CDJ61979.1 - 0.19 11.7 6.5 0.23 11.4 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DUF349 PF03993.7 CDJ61979.1 - 0.21 11.7 11.9 0.061 13.4 3.5 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Myb_Cef PF11831.3 CDJ61979.1 - 0.84 8.8 12.7 0.045 12.9 4.8 1.7 2 0 0 2 2 2 0 pre-mRNA splicing factor component FCP1_C PF09309.5 CDJ61979.1 - 1.2 8.4 16.1 5.7 6.1 11.1 1.9 1 1 0 1 1 1 0 FCP1, C-terminal Cwf_Cwc_15 PF04889.7 CDJ61979.1 - 3.5 7.2 13.7 2 8.0 5.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein G0-G1_switch_2 PF15103.1 CDJ61979.1 - 9.3 6.5 7.4 4 7.7 2.6 2.0 2 0 0 2 2 2 0 G0/G1 switch protein 2 RCR PF12273.3 CDJ61981.1 - 0.016 15.7 7.4 0.025 15.1 5.1 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Herpes_TAF50 PF03326.8 CDJ61981.1 - 0.033 13.1 18.2 0.04 12.8 12.6 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Androgen_recep PF02166.11 CDJ61981.1 - 0.057 12.2 21.4 0.077 11.8 14.8 1.2 1 0 0 1 1 1 0 Androgen receptor CDK2AP PF09806.4 CDJ61981.1 - 0.71 10.0 11.6 0.85 9.8 8.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1556 PF07590.6 CDJ61981.1 - 0.91 9.7 7.4 1.2 9.4 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1556) PAT1 PF09770.4 CDJ61981.1 - 6.8 4.8 25.0 8.2 4.5 17.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ61981.1 - 8.8 6.1 16.7 13 5.5 11.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit rRNA_processing PF08524.6 CDJ61982.1 - 0.00026 20.7 16.1 0.00026 20.7 11.2 2.4 2 1 0 2 2 2 1 rRNA processing SRP-alpha_N PF04086.8 CDJ61982.1 - 0.12 11.7 20.3 0.15 11.4 14.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mitofilin PF09731.4 CDJ61982.1 - 0.64 8.6 25.0 0.81 8.2 17.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Peptidase_S64 PF08192.6 CDJ61982.1 - 2.1 6.5 15.9 2.6 6.2 11.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF966 PF06136.8 CDJ61982.1 - 7.3 5.9 16.1 8.8 5.6 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC27 PF09507.5 CDJ61982.1 - 9.5 5.3 26.8 12 4.9 18.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CBF PF03914.12 CDJ61983.1 - 5e-19 68.3 0.0 6e-18 64.8 0.0 2.7 2 1 0 2 2 2 1 CBF/Mak21 family OAD_gamma PF04277.8 CDJ61983.1 - 1.6 9.1 11.4 2.5 8.5 0.1 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain CBF PF03914.12 CDJ61984.1 - 0.082 12.3 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 CBF/Mak21 family BTK PF00779.14 CDJ61985.1 - 0.0058 16.2 6.8 0.0058 16.2 4.7 3.6 3 1 1 4 4 4 1 BTK motif LIM PF00412.17 CDJ61985.1 - 0.36 10.9 11.1 2.7 8.1 2.3 2.3 2 0 0 2 2 2 0 LIM domain zf-A20 PF01754.11 CDJ61985.1 - 0.73 9.4 0.2 0.73 9.4 0.1 2.7 3 0 0 3 3 3 0 A20-like zinc finger Cytochrom_CIII PF02085.11 CDJ61985.1 - 1.5 8.9 7.6 1.9 8.6 5.3 1.2 1 0 0 1 1 1 0 Class III cytochrome C family eIF2A PF08662.6 CDJ61986.1 - 4.6e-34 117.8 0.0 3.3e-31 108.5 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Med19 PF10278.4 CDJ61986.1 - 0.26 10.9 8.2 3.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 Nudc_N PF14050.1 CDJ61987.1 - 2.6e-17 62.5 0.0 5.3e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 CDJ61987.1 - 4e-07 30.4 0.9 1.5e-05 25.4 0.6 2.3 1 1 0 1 1 1 1 CS domain TFIIA PF03153.8 CDJ61987.1 - 0.0077 16.1 9.9 0.0099 15.8 6.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.6 CDJ61987.1 - 0.096 10.7 10.9 0.14 10.2 7.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Kelch_4 PF13418.1 CDJ61988.1 - 2.8e-40 135.8 6.6 1.1e-10 41.0 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CDJ61988.1 - 3.3e-37 125.8 10.1 1.2e-08 34.8 0.0 7.3 8 0 0 8 8 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ61988.1 - 8.1e-28 95.8 0.0 5.7e-07 29.3 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CDJ61988.1 - 7.8e-24 82.8 2.2 7.9e-05 22.6 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CDJ61988.1 - 7.6e-18 63.7 3.5 1.3e-05 24.5 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CDJ61988.1 - 3.8e-06 26.4 11.9 0.0034 17.0 0.0 6.5 7 1 0 7 7 7 1 Kelch motif APG6 PF04111.7 CDJ61988.1 - 0.0053 15.8 7.0 0.0076 15.3 4.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Atg14 PF10186.4 CDJ61988.1 - 0.017 14.1 4.4 0.023 13.6 3.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 CDJ61988.1 - 0.049 12.8 4.8 0.083 12.0 3.3 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 CDJ61988.1 - 0.057 12.8 9.5 0.098 12.0 6.6 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.7 CDJ61988.1 - 0.079 12.7 3.4 0.15 11.8 2.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 CDJ61988.1 - 0.13 12.2 10.9 0.37 10.8 7.4 2.0 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 CDJ61988.1 - 0.14 12.5 6.4 1.8 9.0 4.4 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 CDJ61988.1 - 0.15 10.4 5.3 0.21 9.9 3.7 1.1 1 0 0 1 1 1 0 AAA domain Sec34 PF04136.10 CDJ61988.1 - 0.18 11.4 3.0 0.29 10.8 2.1 1.2 1 0 0 1 1 1 0 Sec34-like family Prefoldin_3 PF13758.1 CDJ61988.1 - 0.18 11.5 3.1 0.22 11.3 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit GAS PF13851.1 CDJ61988.1 - 0.19 10.9 8.9 0.3 10.2 6.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 CDJ61988.1 - 0.5 10.2 6.8 0.25 11.2 2.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.4 CDJ61988.1 - 0.56 10.3 6.9 2.2 8.4 4.3 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.8 CDJ61988.1 - 0.7 8.8 4.4 1 8.3 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4200 PF13863.1 CDJ61988.1 - 0.96 9.4 8.3 1.7 8.5 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) SNARE PF05739.14 CDJ61988.1 - 1.3 8.7 10.0 7.5 6.3 0.5 2.5 1 1 1 2 2 2 0 SNARE domain Spc7 PF08317.6 CDJ61988.1 - 2.3 6.8 9.9 3.1 6.3 6.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.8 CDJ61988.1 - 4 7.8 8.7 59 4.0 6.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 CDJ61988.1 - 6.6 6.8 10.6 19 5.3 6.9 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain cNMP_binding PF00027.24 CDJ61990.1 - 1.4e-15 56.8 0.0 3.9e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain MTS PF05175.9 CDJ61990.1 - 0.079 12.3 0.1 0.78 9.0 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase small domain Cytochrom_C PF00034.16 CDJ61991.1 - 0.14 13.0 0.8 0.46 11.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c Toxin_7 PF05980.7 CDJ61992.1 - 0.44 10.6 7.2 1 9.4 0.2 2.3 2 0 0 2 2 2 0 Toxin 7 Period_C PF12114.3 CDJ61994.1 - 7.7 6.0 22.5 0.8 9.2 12.1 1.8 1 1 1 2 2 2 0 Period protein 2/3C-terminal region NAP PF00956.13 CDJ61995.1 - 7.7e-49 166.0 0.0 7.7e-49 166.0 0.0 4.8 3 2 1 4 4 4 1 Nucleosome assembly protein (NAP) Med3 PF11593.3 CDJ61995.1 - 0.0017 17.7 2.6 0.0017 17.7 1.8 6.1 4 2 0 4 4 4 1 Mediator complex subunit 3 fungal Neur_chan_memb PF02932.11 CDJ61996.1 - 1.3 8.8 6.6 1.1e+02 2.5 5.5 2.8 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 CDJ61996.1 - 8.8 6.0 12.6 3.5 7.3 4.3 2.5 3 0 0 3 3 3 0 DDHD domain UQ_con PF00179.21 CDJ61997.1 - 1e-17 63.8 0.0 1.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDJ61997.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain RRM_1 PF00076.17 CDJ61998.1 - 0.0017 17.9 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 CDJ61999.1 - 0.00046 18.5 93.0 0.0045 15.2 31.2 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal rve PF00665.21 CDJ62001.1 - 5.1e-16 58.8 0.0 2e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 CDJ62001.1 - 0.0038 16.6 0.9 0.0085 15.4 0.6 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_3 PF13456.1 CDJ62001.1 - 0.021 14.5 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Kringle PF00051.13 CDJ62002.1 - 4.4e-15 55.5 2.6 1e-14 54.3 1.8 1.5 1 0 0 1 1 1 1 Kringle domain GCC2_GCC3 PF07699.8 CDJ62002.1 - 5.1e-15 54.7 37.5 1.4e-05 24.5 3.1 5.9 4 1 1 5 5 5 4 GCC2 and GCC3 Chorion_2 PF03964.10 CDJ62002.1 - 0.012 16.0 2.9 0.012 16.0 2.0 3.8 4 0 0 4 4 4 0 Chorion family 2 BAF1_ABF1 PF04684.8 CDJ62003.1 - 0.17 10.6 9.2 0.35 9.6 6.4 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UBN_AB PF14075.1 CDJ62003.1 - 3 7.4 5.5 0.2 11.3 0.5 1.4 2 0 0 2 2 2 0 Ubinuclein conserved middle domain zf-MIZ PF02891.15 CDJ62004.1 - 2.7e-16 58.8 5.7 6.6e-16 57.5 3.9 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CDJ62004.1 - 0.018 14.5 2.2 0.038 13.4 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Chromo PF00385.19 CDJ62006.1 - 2.7e-11 42.9 0.0 4.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDJ62006.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Mvb12 PF09452.5 CDJ62006.1 - 0.11 12.7 0.1 0.33 11.1 0.1 1.8 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 zf-H2C2 PF09337.5 CDJ62006.1 - 0.12 11.8 0.3 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 CDJ62007.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ62007.1 - 1.9e-07 31.5 0.0 3.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDJ62007.1 - 0.0056 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ62007.1 - 0.0076 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Myf5 PF12232.3 CDJ62007.1 - 0.067 13.8 1.2 0.11 13.1 0.7 1.5 1 1 0 1 1 1 0 Myogenic determination factor 5 DUF1758 PF05585.7 CDJ62007.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) cNMP_binding PF00027.24 CDJ62009.1 - 1e-64 214.3 4.0 4.4e-22 77.7 0.0 4.3 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 CDJ62009.1 - 6.6e-06 25.5 1.5 0.78 9.2 0.0 5.0 5 0 0 5 5 5 2 Cupin domain DHC_N2 PF08393.8 CDJ62011.1 - 2.7e-115 385.1 8.3 2.7e-115 385.1 5.7 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CDJ62011.1 - 1.7e-106 356.9 13.8 6.9e-106 354.9 3.7 4.0 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 SR-25 PF10500.4 CDJ62011.1 - 5.4 6.4 23.1 0.33 10.3 11.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_6 PF12774.2 CDJ62012.1 - 2.4e-17 63.2 0.0 2.4e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CDJ62013.1 - 1.2e-86 289.2 0.7 2.4e-86 288.2 0.5 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDJ62013.1 - 9.3e-86 287.1 0.0 1.1e-84 283.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CDJ62013.1 - 1.9e-74 250.2 0.4 3.4e-74 249.3 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 CDJ62013.1 - 6.6e-61 205.9 15.3 1.8e-60 204.4 10.8 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_6 PF12774.2 CDJ62013.1 - 2.2e-25 89.5 0.1 4.6e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CDJ62013.1 - 5.9e-16 58.4 0.0 1.5e-05 24.6 0.0 4.5 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDJ62013.1 - 7.2e-06 26.1 8.1 0.00041 20.3 0.0 5.1 5 1 1 6 6 5 1 AAA ATPase domain ABC_tran PF00005.22 CDJ62013.1 - 5.7e-05 23.4 1.7 0.00091 19.5 0.0 3.1 4 0 0 4 4 2 1 ABC transporter AAA_29 PF13555.1 CDJ62013.1 - 0.00015 21.1 0.0 0.01 15.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 CDJ62013.1 - 0.0014 17.6 0.0 0.061 12.2 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CDJ62013.1 - 0.0016 18.3 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CDJ62013.1 - 0.0027 17.4 0.0 1.4 8.6 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CDJ62013.1 - 0.0051 16.6 0.0 0.29 11.0 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CDJ62013.1 - 0.0061 16.6 0.8 0.11 12.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.15 CDJ62013.1 - 0.013 14.2 0.0 0.013 14.2 0.0 2.5 2 1 0 2 2 1 0 G-protein alpha subunit Mg_chelatase PF01078.16 CDJ62013.1 - 0.016 14.3 0.0 1.1 8.3 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF4061 PF13270.1 CDJ62013.1 - 0.016 15.2 2.7 0.21 11.7 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) ATP-synt_ab PF00006.20 CDJ62013.1 - 0.024 14.1 0.1 2.1 7.7 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 CDJ62013.1 - 0.037 14.8 0.1 4.2 8.2 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 CDJ62013.1 - 0.047 13.9 0.0 0.95 9.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain Dynein_heavy PF03028.10 CDJ62014.1 - 2.9e-42 144.6 0.0 3.7e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Dynein_heavy PF03028.10 CDJ62015.1 - 3.5e-158 527.8 0.0 8.6e-146 486.8 0.0 2.0 1 1 1 2 2 2 2 Dynein heavy chain and region D6 of dynein motor SWM_repeat PF13753.1 CDJ62016.1 - 0.05 12.6 3.2 0.082 11.9 2.2 1.4 1 1 0 1 1 1 0 Putative flagellar system-associated repeat KRE9 PF05390.6 CDJ62016.1 - 0.073 13.4 1.0 0.42 10.9 0.4 2.3 2 1 1 3 3 3 0 Yeast cell wall synthesis protein KRE9/KNH1 ATC_hydrolase PF14196.1 CDJ62016.1 - 0.16 12.4 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase CCDC74_C PF14917.1 CDJ62018.1 - 0.049 13.7 2.5 0.06 13.4 1.7 1.0 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal LRR_4 PF12799.2 CDJ62020.1 - 4.8e-15 54.7 15.9 3.7e-09 35.9 0.3 3.6 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ62020.1 - 2.5e-12 46.3 11.0 0.00012 21.8 0.4 3.2 3 0 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 CDJ62020.1 - 2.3e-10 39.4 9.8 0.001 18.9 0.0 5.7 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 CDJ62020.1 - 7.4e-06 25.3 16.2 2.5 8.6 0.0 6.4 6 0 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 CDJ62020.1 - 6e-05 22.5 11.9 0.13 12.3 0.0 5.7 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.1 CDJ62020.1 - 0.00016 21.2 0.7 0.061 12.8 0.2 2.1 2 0 0 2 2 2 2 Leucine-rich repeat zf-CpG_bind_C PF12269.3 CDJ62021.1 - 0.07 12.6 0.1 0.079 12.4 0.1 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain LRR_8 PF13855.1 CDJ62022.1 - 4.8e-05 23.0 5.0 0.0017 18.1 0.1 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CDJ62022.1 - 0.0025 17.4 4.3 0.1 12.2 0.6 3.0 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDJ62022.1 - 0.023 14.6 2.5 0.43 10.8 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.1 CDJ62022.1 - 0.15 11.6 0.2 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 Leucine-rich repeat LRR_7 PF13504.1 CDJ62022.1 - 1.2 9.6 10.4 2.5 8.6 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 CDJ62023.1 - 3.7e-31 106.2 30.7 5.4e-06 25.9 0.4 7.8 3 2 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ62023.1 - 6.5e-30 102.6 19.9 1.4e-07 31.0 0.1 5.6 2 2 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.1 CDJ62023.1 - 5.1e-25 88.0 1.3 1.3e-12 47.5 0.0 3.0 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 CDJ62023.1 - 9.7e-14 49.3 32.1 0.018 14.9 0.0 10.3 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.1 CDJ62023.1 - 3.1e-13 48.2 20.3 0.079 13.0 0.0 9.8 8 1 2 10 10 10 5 Leucine Rich repeat LRR_7 PF13504.1 CDJ62023.1 - 1.1e-10 39.8 28.1 1.9 9.0 0.0 10.9 11 0 0 11 11 11 5 Leucine rich repeat DUF3654 PF12376.3 CDJ62024.1 - 0.071 12.9 0.1 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) DUF202 PF02656.10 CDJ62025.1 - 1.3 9.3 4.5 1.4 9.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Secretin_N_2 PF07655.8 CDJ62026.1 - 0.049 14.0 12.8 0.065 13.6 8.8 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Bul1_C PF04426.7 CDJ62026.1 - 0.085 12.0 1.9 0.11 11.7 1.3 1.1 1 0 0 1 1 1 0 Bul1 C terminus KdpA PF03814.10 CDJ62026.1 - 0.1 10.5 0.2 0.12 10.3 0.1 1.0 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit DUF3633 PF12315.3 CDJ62026.1 - 0.1 11.8 4.6 0.14 11.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) DUF515 PF04415.7 CDJ62026.1 - 0.17 10.1 6.3 0.16 10.1 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) GP40 PF11025.3 CDJ62026.1 - 0.61 9.6 6.9 0.83 9.2 4.8 1.2 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium CDK2AP PF09806.4 CDJ62026.1 - 0.64 10.2 8.2 0.77 9.9 5.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Macoilin PF09726.4 CDJ62026.1 - 0.79 7.9 8.0 0.82 7.8 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Myco_19_kDa PF05481.7 CDJ62026.1 - 1 9.1 5.3 1.2 8.9 3.7 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen AF-4 PF05110.8 CDJ62026.1 - 1.5 6.5 20.8 1.6 6.4 14.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SSP160 PF06933.6 CDJ62026.1 - 3.5 5.4 13.8 3.9 5.3 9.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1635 PF07795.6 CDJ62026.1 - 4.1 6.7 6.0 4.6 6.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CAF-1_p150 PF11600.3 CDJ62026.1 - 6 6.1 12.1 7.5 5.8 8.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Apt1 PF10351.4 CDJ62026.1 - 7.5 5.2 8.9 8.5 5.1 6.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Corona_nucleoca PF00937.13 CDJ62026.1 - 9.6 5.0 11.0 11 4.7 7.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein zf-C3HC4_2 PF13923.1 CDJ62027.1 - 0.014 15.4 0.6 0.019 14.9 0.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ62027.1 - 0.015 15.0 3.0 0.03 14.1 2.1 1.5 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 CDJ62027.1 - 0.23 11.1 5.3 1.1 8.9 3.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.14 CDJ62028.1 - 7.1 7.0 19.3 0.49 10.8 7.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_S8 PF00082.17 CDJ62030.1 - 2.7e-13 49.6 0.5 2.7e-13 49.6 0.3 3.3 4 0 0 4 4 4 1 Subtilase family DUF2828 PF11443.3 CDJ62030.1 - 0.091 10.9 8.9 0.12 10.4 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EphA2_TM PF14575.1 CDJ62030.1 - 2.9 8.3 5.1 17 5.8 0.8 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain rve PF00665.21 CDJ62031.1 - 0.016 15.3 0.1 0.23 11.5 0.0 2.0 1 1 1 2 2 2 0 Integrase core domain DUF3038 PF11237.3 CDJ62031.1 - 0.062 13.1 0.3 0.084 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) DUF2070 PF09843.4 CDJ62031.1 - 0.065 12.6 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_L44 PF00935.14 CDJ62033.1 - 1.5e-33 114.5 10.7 1.9e-33 114.2 7.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 CDJ62033.1 - 2.5 8.4 9.8 3.2 8.0 0.8 2.6 2 1 0 2 2 2 0 Ribosomal protein L33 DUF755 PF05501.6 CDJ62035.1 - 0.0074 16.3 17.8 0.0074 16.3 12.4 10.5 9 2 1 10 10 10 1 Domain of unknown function (DUF755) BAF1_ABF1 PF04684.8 CDJ62036.1 - 0.0042 15.9 9.4 0.0042 15.9 6.5 2.2 2 1 1 3 3 2 1 BAF1 / ABF1 chromatin reorganising factor Exosortase_EpsH PF09721.5 CDJ62036.1 - 0.012 14.8 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) YajC PF02699.10 CDJ62036.1 - 0.024 14.2 0.3 0.024 14.2 0.2 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit Pex14_N PF04695.8 CDJ62036.1 - 0.19 11.7 11.2 0.06 13.4 4.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 CDJ62036.1 - 0.54 9.5 6.2 0.77 9.0 2.6 2.0 2 0 0 2 2 2 0 Spt20 family DUF4557 PF15101.1 CDJ62036.1 - 0.77 9.5 7.9 4.4 7.0 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF2489 PF10675.4 CDJ62036.1 - 0.99 9.0 16.9 0.5 10.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF202 PF02656.10 CDJ62036.1 - 1 9.6 5.6 0.58 10.4 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) PHD_3 PF13922.1 CDJ62036.1 - 1.4 9.2 10.8 0.85 9.9 2.4 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx RCR PF12273.3 CDJ62036.1 - 1.5 9.3 9.6 2.9 8.4 4.8 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF4131 PF13567.1 CDJ62036.1 - 1.5 8.1 11.8 0.013 14.8 2.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) BRF1 PF07741.8 CDJ62036.1 - 1.8 8.8 5.3 1.1 9.4 0.7 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Suf PF05843.9 CDJ62036.1 - 2.8 7.6 7.8 2.8 7.5 3.4 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.14 CDJ62036.1 - 4.5 7.7 8.6 1.3 9.4 2.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein KR PF08659.5 CDJ62037.1 - 4.3e-33 114.4 0.0 4.7e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CDJ62037.1 - 6.8e-29 100.9 0.0 7.4e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase ketoacyl-synt PF00109.21 CDJ62038.1 - 5e-128 425.9 1.0 1.2e-76 257.6 0.0 3.8 2 1 1 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CDJ62038.1 - 5.2e-127 420.5 0.2 1.8e-58 197.1 0.0 3.7 3 0 0 3 3 3 3 KR domain adh_short PF00106.20 CDJ62038.1 - 1.1e-105 350.7 1.8 1.1e-46 158.8 0.0 4.9 4 0 0 4 4 4 3 short chain dehydrogenase PS-DH PF14765.1 CDJ62038.1 - 3.7e-89 298.7 5.2 3.8e-48 164.1 0.1 2.4 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 CDJ62038.1 - 1.6e-83 276.3 8.5 6.4e-42 142.1 0.2 3.4 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 CDJ62038.1 - 2e-56 191.6 0.3 3.6e-56 190.8 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain ADH_zinc_N PF00107.21 CDJ62038.1 - 2.1e-30 104.9 0.1 8.4e-16 57.6 0.0 4.3 4 0 0 4 4 4 3 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDJ62038.1 - 2.1e-18 67.4 0.0 1.2e-07 32.6 0.0 3.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Epimerase PF01370.16 CDJ62038.1 - 8.4e-16 58.1 0.0 3.2e-06 26.7 0.0 3.4 3 0 0 3 3 3 3 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 CDJ62038.1 - 2.6e-14 52.9 3.6 5.9e-06 26.0 0.0 3.5 3 0 0 3 3 3 2 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 CDJ62038.1 - 2.3e-12 47.0 0.0 5.4e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 CDJ62038.1 - 2.4e-10 39.5 0.0 9.9e-05 21.1 0.0 3.5 3 0 0 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CDJ62038.1 - 7e-10 38.2 0.0 0.002 17.0 0.0 3.4 3 0 0 3 3 3 3 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 CDJ62038.1 - 9e-08 32.1 0.0 0.023 14.4 0.0 3.1 3 0 0 3 3 2 2 Enoyl-(Acyl carrier protein) reductase AlaDh_PNT_C PF01262.16 CDJ62038.1 - 0.0002 20.9 1.0 0.26 10.8 0.1 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thiolase_N PF00108.18 CDJ62038.1 - 0.0029 16.6 0.1 0.0096 14.9 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain ELFV_dehydrog PF00208.16 CDJ62038.1 - 0.19 11.3 11.9 1.6 8.2 0.0 4.6 4 1 0 5 5 5 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF3391 PF11871.3 CDJ62039.1 - 1.2 9.3 5.3 0.37 10.9 1.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Scramblase PF03803.10 CDJ62041.1 - 0.058 12.4 0.0 0.068 12.2 0.0 1.1 1 0 0 1 1 1 0 Scramblase rve PF00665.21 CDJ62042.1 - 9.3e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 CDJ62043.1 - 9.5e-09 35.4 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDJ62043.1 - 0.00046 19.8 0.2 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain GLTSCR1 PF15249.1 CDJ62043.1 - 0.033 14.2 0.1 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region SASRP1 PF15160.1 CDJ62044.1 - 0.12 11.6 4.0 0.15 11.2 2.8 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Kinase-like PF14531.1 CDJ62045.1 - 1.2e-07 31.0 0.0 2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDJ62045.1 - 1.4e-07 30.9 0.0 2.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62045.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase MOZART1 PF12554.3 CDJ62046.1 - 1.6e-19 69.1 0.4 2.2e-19 68.6 0.3 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated p450 PF00067.17 CDJ62046.1 - 0.017 13.6 0.2 0.017 13.6 0.1 1.0 1 0 0 1 1 1 0 Cytochrome P450 Tubulin PF00091.20 CDJ62047.1 - 9.9e-71 237.9 0.0 1.6e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDJ62047.1 - 3.5e-49 166.0 0.1 5.3e-49 165.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CDJ62047.1 - 9.8e-05 22.3 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CDJ62047.1 - 0.007 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF202 PF02656.10 CDJ62048.1 - 0.00018 21.6 0.0 0.091 12.9 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF202) DUF4131 PF13567.1 CDJ62048.1 - 0.15 11.4 0.3 0.29 10.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HAD_2 PF13419.1 CDJ62050.1 - 0.0012 19.1 0.0 0.042 14.0 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDJ62050.1 - 0.019 15.3 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 CDJ62050.1 - 0.047 13.3 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase LRR_4 PF12799.2 CDJ62052.1 - 1.2e-13 50.3 0.3 0.00079 18.9 0.0 5.3 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ62052.1 - 6.4e-12 45.0 6.0 1.6e-08 34.1 0.0 3.5 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CDJ62052.1 - 0.00016 21.4 2.7 59 4.2 0.0 6.7 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.28 CDJ62052.1 - 0.00058 19.5 5.9 17 5.8 0.0 7.2 6 3 1 7 7 7 1 Leucine Rich Repeat F-box-like_2 PF13013.1 CDJ62052.1 - 0.0065 16.1 0.4 0.21 11.3 0.2 2.9 1 1 0 1 1 1 1 F-box-like domain LRR_7 PF13504.1 CDJ62052.1 - 0.021 14.9 13.0 91 3.9 0.0 8.4 9 1 0 9 9 9 0 Leucine rich repeat adh_short PF00106.20 CDJ62053.1 - 1.2e-19 70.8 2.4 4.9e-17 62.3 1.7 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CDJ62053.1 - 1.8e-08 34.2 1.4 1.3e-06 28.1 1.0 2.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDJ62053.1 - 5.4e-05 23.0 0.2 8.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CDJ62053.1 - 0.00096 18.8 0.5 0.0025 17.5 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 CDJ62053.1 - 0.045 12.6 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 CDJ62053.1 - 0.068 12.2 0.5 0.18 10.9 0.3 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 CDJ62053.1 - 0.089 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ExoD PF06055.7 CDJ62053.1 - 1.7 7.7 6.8 3.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Thioredoxin_7 PF13899.1 CDJ62056.1 - 3.3e-08 33.4 0.3 6.9e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 CDJ62056.1 - 2.8e-07 29.9 0.0 5.9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain RAP1 PF07218.6 CDJ62056.1 - 1.5 6.8 5.1 1.9 6.4 3.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ABC_tran PF00005.22 CDJ62057.1 - 2.3e-65 219.0 0.0 5.8e-33 114.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CDJ62057.1 - 3.3e-54 184.1 19.1 1.4e-38 132.9 2.0 3.3 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 CDJ62057.1 - 5.8e-14 51.8 6.4 7.7e-07 28.5 0.7 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CDJ62057.1 - 2.4e-12 47.2 1.9 2.9e-05 24.1 0.4 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 CDJ62057.1 - 1.2e-11 45.1 0.0 0.35 10.7 0.0 4.3 2 2 0 4 4 4 4 AAA domain AAA_29 PF13555.1 CDJ62057.1 - 1.3e-08 34.2 0.0 0.0043 16.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CDJ62057.1 - 1.7e-08 33.7 0.0 0.0019 17.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDJ62057.1 - 2e-08 34.4 1.7 0.026 14.6 0.2 4.0 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CDJ62057.1 - 2.5e-08 34.7 0.0 0.015 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 CDJ62057.1 - 2.9e-08 32.7 2.1 0.016 13.8 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_30 PF13604.1 CDJ62057.1 - 7.4e-07 28.9 0.0 0.024 14.1 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CDJ62057.1 - 1.1e-06 28.1 0.2 0.41 10.0 0.0 4.2 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 CDJ62057.1 - 8.1e-06 25.6 2.7 0.048 13.5 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CDJ62057.1 - 8.7e-06 25.9 0.0 0.16 12.1 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDJ62057.1 - 1.1e-05 25.2 0.0 0.072 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CDJ62057.1 - 2.1e-05 24.8 1.5 1.1 9.6 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 CDJ62057.1 - 2.2e-05 24.4 0.4 0.089 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 CDJ62057.1 - 5.2e-05 22.8 0.1 0.43 10.0 0.0 3.1 3 0 0 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 CDJ62057.1 - 0.00013 21.4 0.3 5 6.5 0.1 3.7 3 0 0 3 3 3 0 IstB-like ATP binding protein NB-ARC PF00931.17 CDJ62057.1 - 0.00039 19.3 0.1 0.2 10.4 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.1 CDJ62057.1 - 0.00043 20.1 0.8 1.1 9.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain NTPase_1 PF03266.10 CDJ62057.1 - 0.0012 18.5 1.2 3.1 7.4 0.1 4.0 4 0 0 4 4 4 1 NTPase Rad17 PF03215.10 CDJ62057.1 - 0.0025 16.5 0.4 0.83 8.2 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein G-alpha PF00503.15 CDJ62057.1 - 0.0026 16.5 0.9 1.7 7.2 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit AAA_23 PF13476.1 CDJ62057.1 - 0.0027 18.0 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CDJ62057.1 - 0.0046 17.4 0.3 3.6 8.1 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein PRK PF00485.13 CDJ62057.1 - 0.0059 16.1 0.1 3.7 7.0 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family KaiC PF06745.8 CDJ62057.1 - 0.0069 15.5 0.7 7.7 5.5 0.0 3.6 3 0 0 3 3 3 0 KaiC RNA_helicase PF00910.17 CDJ62057.1 - 0.0081 16.3 0.2 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 CDJ62057.1 - 0.011 14.9 0.8 3.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.18 CDJ62057.1 - 0.011 15.6 0.6 9.7 6.1 0.1 3.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CDJ62057.1 - 0.017 15.0 0.0 3.1 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CDJ62057.1 - 0.018 14.5 0.3 8 5.9 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 CDJ62057.1 - 0.024 14.1 0.3 8.1 5.8 0.0 3.0 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 CDJ62057.1 - 0.031 13.7 0.0 2.3 7.6 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 CDJ62057.1 - 0.057 12.4 0.0 6 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 CDJ62057.1 - 0.063 12.9 5.1 5.5 6.6 0.0 3.6 4 0 0 4 4 4 0 NACHT domain DUF815 PF05673.8 CDJ62057.1 - 0.068 12.0 0.0 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Thioredoxin PF00085.15 CDJ62058.1 - 1.5e-18 66.3 0.5 1.1e-06 28.1 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 CDJ62058.1 - 1.6e-15 57.4 7.2 1.2e-10 41.4 2.3 2.9 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDJ62058.1 - 1.9e-09 37.5 0.8 0.058 13.5 0.0 3.7 3 0 0 3 3 3 3 Thioredoxin-like Thioredoxin_2 PF13098.1 CDJ62058.1 - 0.00015 21.9 0.5 0.21 11.8 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain TrbC_Ftype PF09673.5 CDJ62058.1 - 0.0021 17.6 0.8 1 8.9 0.0 3.4 2 1 2 4 4 4 2 Type-F conjugative transfer system pilin assembly protein HyaE PF07449.6 CDJ62058.1 - 0.024 14.5 0.1 1.6 8.6 0.0 3.0 3 1 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Peptidase_C12 PF01088.16 CDJ62059.1 - 2.8e-17 62.6 0.0 3.2e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.20 CDJ62060.1 - 1.8e-06 27.3 0.3 6.5e-06 25.4 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62060.1 - 0.0047 16.0 0.1 0.01 14.9 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Fumble PF03630.9 CDJ62061.1 - 2.7e-34 118.5 11.1 6.3e-23 81.1 0.1 4.4 3 1 2 5 5 5 3 Fumble SAPS PF04499.10 CDJ62061.1 - 0.0089 14.7 8.4 0.22 10.1 5.8 2.6 1 1 0 1 1 1 1 SIT4 phosphatase-associated protein Band_3_cyto PF07565.8 CDJ62061.1 - 0.41 10.1 20.3 1.4 8.3 3.7 3.7 4 0 0 4 4 4 0 Band 3 cytoplasmic domain DUF4483 PF14825.1 CDJ62061.1 - 9.1 5.8 27.9 1.5 8.4 0.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4483) DXP_synthase_N PF13292.1 CDJ62062.1 - 3.2e-26 91.8 0.0 6.1e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DXP_synthase_N PF13292.1 CDJ62063.1 - 2.4e-48 164.4 0.0 4e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 CDJ62063.1 - 4.5e-16 58.8 0.0 1.1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_N PF00456.16 CDJ62063.1 - 3.8e-05 22.6 0.0 0.075 11.8 0.0 2.4 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.15 CDJ62063.1 - 0.00045 19.0 0.1 0.001 17.8 0.0 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component Corona_nucleoca PF00937.13 CDJ62063.1 - 0.97 8.3 7.7 8 5.2 0.0 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Pex14_N PF04695.8 CDJ62063.1 - 1.6 8.8 11.8 13 5.8 0.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FKBP_N PF01346.13 CDJ62063.1 - 5.7 7.0 10.1 3.5 7.6 1.8 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Pex14_N PF04695.8 CDJ62064.1 - 2.1 8.4 19.8 2.7 8.0 0.3 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDJ62064.1 - 8.8 5.2 24.9 21 4.0 3.4 3.0 3 0 0 3 3 3 0 Fms-interacting protein CwfJ_C_1 PF04677.10 CDJ62065.1 - 2e-24 85.5 0.0 3.2e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CDJ62065.1 - 2.4e-10 40.7 0.1 6.7e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 RRM_1 PF00076.17 CDJ62065.1 - 1.2e-07 31.1 0.0 2.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ62065.1 - 4.5e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ62065.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AhpC-TSA PF00578.16 CDJ62066.1 - 2.4e-30 104.7 0.0 3.1e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDJ62066.1 - 2.1e-12 46.7 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CDJ62066.1 - 3.5e-09 36.1 0.2 6e-09 35.4 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 CDJ62066.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Orthopox_C10L PF07020.6 CDJ62067.1 - 0.88 10.1 133.8 1.2 9.7 7.8 9.9 2 2 3 5 5 5 0 Orthopoxvirus C10L protein Octopine_DH PF02317.12 CDJ62068.1 - 3.9e-27 94.7 0.0 5.5e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 CDJ62068.1 - 5.6e-05 22.9 0.1 0.00022 21.0 0.1 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.12 CDJ62068.1 - 0.00023 20.1 0.1 0.00041 19.3 0.1 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 CDJ62068.1 - 0.00042 20.6 0.5 0.0014 19.0 0.0 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CDJ62068.1 - 0.0059 16.0 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 CDJ62068.1 - 0.035 14.4 0.0 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CDJ62068.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Herpes_LAMP2 PF06126.6 CDJ62069.1 - 0.24 9.7 1.6 0.28 9.5 1.1 1.2 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 zf-DHHC PF01529.15 CDJ62069.1 - 0.57 9.5 2.4 0.62 9.4 1.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3021 PF11457.3 CDJ62069.1 - 0.94 9.3 11.8 1.3 8.8 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DUF3671 PF12420.3 CDJ62069.1 - 2.5 8.0 7.6 3.2 7.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function ASFV_J13L PF05568.6 CDJ62069.1 - 4.4 6.8 9.3 0.17 11.3 0.9 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein ABC2_membrane_3 PF12698.2 CDJ62069.1 - 5.1 6.0 13.0 6.3 5.7 9.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2393 PF09624.5 CDJ62069.1 - 6 6.3 7.5 8 5.9 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) MCM_bind PF09739.4 CDJ62070.1 - 6.6e-07 28.9 1.1 6.6e-07 28.9 0.8 3.9 5 0 0 5 5 5 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 CDJ62070.1 - 5.5e-05 23.3 0.0 0.00025 21.2 0.0 2.2 3 0 0 3 3 3 1 Putative alanine racemase RAB3GAP2_N PF14655.1 CDJ62070.1 - 0.0074 15.3 0.9 0.0074 15.3 0.6 4.7 4 1 0 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Pex14_N PF04695.8 CDJ62070.1 - 0.016 15.2 2.4 0.016 15.2 1.6 5.6 5 1 0 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_IE2_3 PF03361.9 CDJ62070.1 - 0.016 14.5 1.1 0.042 13.1 0.8 1.7 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Med15 PF09606.5 CDJ62070.1 - 0.021 13.0 62.2 0.027 12.6 3.3 3.5 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal 7tm_1 PF00001.16 CDJ62070.1 - 1.4 8.0 7.2 0.13 11.3 0.1 2.5 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) RAP PF08373.5 CDJ62071.1 - 0.03 14.1 0.2 0.03 14.1 0.1 2.2 3 0 0 3 3 3 0 RAP domain DUF559 PF04480.7 CDJ62071.1 - 0.037 13.6 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF559) SR-25 PF10500.4 CDJ62071.1 - 3.1 7.2 7.2 7.2 6.0 5.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAST_1 PF06743.10 CDJ62071.1 - 6.7 6.4 9.5 25 4.6 0.4 4.2 4 2 2 6 6 6 0 FAST kinase-like protein, subdomain 1 AP-5_subunit_s1 PF15001.1 CDJ62072.1 - 2.2e-24 86.4 0.3 8e-23 81.3 0.2 2.2 1 1 0 1 1 1 1 AP-5 complex subunit sigma-1 B9-C2 PF07162.6 CDJ62073.1 - 3.1e-18 66.1 0.1 4.4e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF3558 PF12079.3 CDJ62073.1 - 0.0075 15.9 0.3 0.0099 15.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) RNA_GG_bind PF10258.4 CDJ62074.1 - 4.3e-18 64.7 0.1 1.2e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_2 PF12796.2 CDJ62075.1 - 2.4e-13 50.2 0.2 1.2e-08 35.1 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ62075.1 - 5.5e-12 44.8 3.7 0.00012 21.7 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CDJ62075.1 - 1.2e-08 35.1 0.4 1.7e-05 25.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ62075.1 - 8.3e-08 31.7 0.1 0.05 13.8 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CDJ62075.1 - 4.5e-06 26.7 0.6 0.0063 16.7 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RAP1 PF07218.6 CDJ62075.1 - 4.5 5.2 8.8 7.8 4.4 6.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RRM_6 PF14259.1 CDJ62076.1 - 1.8e-13 50.2 0.0 2.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ62076.1 - 3.3e-08 33.0 0.1 5e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAGAT PF03982.8 CDJ62076.1 - 0.071 11.7 0.0 0.092 11.4 0.0 1.1 1 0 0 1 1 1 0 Diacylglycerol acyltransferase FimP PF09766.4 CDJ62078.1 - 2e-09 36.9 4.1 2e-09 36.9 2.9 2.2 2 0 0 2 2 2 1 Fms-interacting protein Methyltransf_32 PF13679.1 CDJ62078.1 - 4.6e-08 32.8 10.9 4.7e-08 32.8 5.5 2.4 2 0 0 2 2 2 1 Methyltransferase domain IncA PF04156.9 CDJ62078.1 - 0.001 18.7 1.8 0.001 18.7 1.2 3.7 2 1 1 3 3 2 1 IncA protein Spt20 PF12090.3 CDJ62078.1 - 0.0024 17.2 12.4 0.25 10.6 3.7 2.4 2 0 0 2 2 2 2 Spt20 family Gti1_Pac2 PF09729.4 CDJ62078.1 - 0.012 15.4 3.6 0.34 10.7 0.1 2.9 3 0 0 3 3 3 0 Gti1/Pac2 family Pex14_N PF04695.8 CDJ62078.1 - 0.013 15.5 5.4 0.013 15.5 3.8 5.0 4 2 1 5 5 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.3 CDJ62078.1 - 0.017 14.1 0.4 0.017 14.1 0.3 3.5 3 1 1 4 4 3 0 Protein of unknown function (DUF2722) SR-25 PF10500.4 CDJ62078.1 - 0.24 10.8 40.5 0.068 12.6 1.4 3.8 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Band_3_cyto PF07565.8 CDJ62078.1 - 0.38 10.2 12.5 0.08 12.4 1.5 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Herpes_gE PF02480.11 CDJ62078.1 - 0.69 8.1 7.4 0.82 7.8 3.9 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ycf1 PF05758.7 CDJ62078.1 - 0.89 7.1 9.0 1.8 6.2 6.1 1.4 1 1 0 1 1 1 0 Ycf1 Suf PF05843.9 CDJ62078.1 - 0.92 9.1 27.1 0.02 14.6 4.2 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Band_7 PF01145.20 CDJ62079.1 - 3.7e-23 82.3 0.2 6.4e-23 81.5 0.0 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family YopH_N PF09013.5 CDJ62079.1 - 0.052 13.2 0.6 0.1 12.2 0.4 1.5 1 0 0 1 1 1 0 YopH, N-terminal Ribosomal_L31e PF01198.14 CDJ62080.1 - 0.03 13.9 0.1 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L31e DUF3243 PF11588.3 CDJ62080.1 - 0.059 13.3 0.9 0.074 13.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) DUF1311 PF07007.7 CDJ62080.1 - 0.061 13.4 0.2 0.075 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) Rab3-GTPase_cat PF13890.1 CDJ62080.1 - 0.11 11.8 1.2 0.13 11.5 0.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit TH1 PF04858.8 CDJ62081.1 - 0.97 7.5 3.1 0.51 8.4 0.9 1.4 1 1 0 1 1 1 0 TH1 protein SseC PF04888.7 CDJ62081.1 - 1.3 8.2 28.7 0.011 15.0 8.9 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Asp_protease_2 PF13650.1 CDJ62082.1 - 1.7e-09 38.0 0.0 3.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ62082.1 - 6e-08 32.3 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ62082.1 - 7.3e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CDJ62082.1 - 0.00082 19.2 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 CDJ62082.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 CDJ62082.1 - 0.038 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.5 CDJ62082.1 - 0.067 12.6 0.3 0.15 11.5 0.2 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger DUF3552 PF12072.3 CDJ62082.1 - 0.076 12.2 0.7 0.12 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) rve PF00665.21 CDJ62083.1 - 1.5e-11 44.4 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 CDJ62084.1 - 7.5e-15 55.0 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ62084.1 - 0.12 11.8 0.8 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.12 CDJ62085.1 - 0.0053 16.8 0.0 0.023 14.7 0.0 2.0 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 CDJ62086.1 - 4.6e-09 36.6 0.0 9.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDJ62086.1 - 3.4e-07 30.1 0.0 8.9e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CDJ62086.1 - 9.4e-07 28.5 0.0 2.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ62086.1 - 0.00016 21.5 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ62086.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease DUF3552 PF12072.3 CDJ62086.1 - 0.19 10.9 0.2 0.29 10.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RVT_1 PF00078.22 CDJ62087.1 - 1.3e-09 37.7 0.0 2.1e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDJ62088.1 - 1.5e-12 46.9 0.0 3.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF367 PF04034.8 CDJ62089.1 - 4.2e-27 94.2 0.0 6e-27 93.7 0.0 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF367) HSP70 PF00012.15 CDJ62090.1 - 3.8e-274 910.2 4.8 4.3e-274 910.0 3.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CDJ62090.1 - 4.3e-15 55.1 0.2 7.6e-13 47.7 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 CDJ62090.1 - 0.0007 18.7 0.9 0.012 14.7 0.1 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CDJ62090.1 - 0.0013 18.3 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CDJ62090.1 - 0.007 15.2 0.7 0.35 9.6 0.1 2.4 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Med15 PF09606.5 CDJ62092.1 - 6.9e-05 21.2 22.4 6.9e-05 21.2 15.5 1.6 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Pkinase PF00069.20 CDJ62092.1 - 0.0034 16.5 0.0 0.0034 16.5 0.0 3.0 3 0 0 3 3 3 1 Protein kinase domain RR_TM4-6 PF06459.7 CDJ62092.1 - 3 7.6 7.2 6.2 6.6 5.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAGA-Tad1 PF12767.2 CDJ62092.1 - 4.7 6.8 17.0 1.4 8.5 9.6 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Band_3_cyto PF07565.8 CDJ62092.1 - 5.5 6.4 9.2 12 5.3 6.4 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain Pkinase PF00069.20 CDJ62094.1 - 1.6e-10 40.5 0.0 3.7e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62094.1 - 0.038 13.0 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 CDJ62095.1 - 8.1e-10 38.2 0.0 4.2e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain PIP5K PF01504.13 CDJ62096.1 - 4.7e-45 153.6 0.0 5.4e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF605 PF04652.11 CDJ62097.1 - 0.0048 16.3 37.1 0.0048 16.3 25.7 2.6 2 1 0 2 2 2 1 Vta1 like EF-hand_1 PF00036.27 CDJ62097.1 - 0.0054 15.9 0.1 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 EF hand VIT1 PF01988.14 CDJ62097.1 - 0.0074 15.7 1.6 0.0074 15.7 1.1 2.7 2 1 1 3 3 3 1 VIT family EF-hand_6 PF13405.1 CDJ62097.1 - 0.019 14.7 0.3 0.063 13.2 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.1 CDJ62097.1 - 0.021 14.4 0.1 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair SOBP PF15279.1 CDJ62097.1 - 9.4 6.5 49.8 2.7 8.3 7.9 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein HSP70 PF00012.15 CDJ62098.1 - 6.9e-12 44.0 3.5 6.9e-12 44.0 2.4 5.7 5 1 1 6 6 6 3 Hsp70 protein zf-HC5HC2H_2 PF13832.1 CDJ62099.1 - 3.9e-05 23.6 8.3 3.9e-05 23.6 5.7 3.5 3 0 0 3 3 3 2 PHD-zinc-finger like domain DUF755 PF05501.6 CDJ62099.1 - 0.0017 18.3 13.2 0.0017 18.3 9.1 16.0 15 2 0 15 15 15 2 Domain of unknown function (DUF755) zf-HC5HC2H PF13771.1 CDJ62099.1 - 0.002 18.2 6.2 0.002 18.2 4.3 4.3 3 1 0 3 3 3 2 PHD-like zinc-binding domain Erv26 PF04148.8 CDJ62099.1 - 4.7 6.5 0.4 28 4.0 0.3 2.3 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 DEAD PF00270.24 CDJ62101.1 - 2.2e-31 108.6 0.0 3.1e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_S66 PF02016.10 CDJ62103.1 - 0.19 10.6 2.2 0.13 11.1 0.7 1.4 1 1 0 1 1 1 0 LD-carboxypeptidase SurE PF01975.12 CDJ62103.1 - 0.55 9.5 4.4 0.49 9.6 2.5 1.4 1 1 0 1 1 1 0 Survival protein SurE DUF3357 PF11837.3 CDJ62103.1 - 0.81 9.5 5.6 8.4 6.3 3.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) AAA_23 PF13476.1 CDJ62103.1 - 0.99 9.6 9.3 1.3 9.3 6.5 1.1 1 0 0 1 1 1 0 AAA domain Gly-zipper_OmpA PF13436.1 CDJ62103.1 - 4.2 7.0 24.8 6.7 6.4 17.2 1.5 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Viral_P18 PF04521.8 CDJ62103.1 - 5.5 6.4 10.3 0.31 10.4 3.5 1.7 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4551 PF15087.1 CDJ62103.1 - 5.9 5.1 9.7 6.4 5.0 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3446 PF11928.3 CDJ62104.1 - 0.012 15.7 7.3 0.022 14.9 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) BORG_CEP PF14957.1 CDJ62106.1 - 4.5 8.2 18.5 5.3 7.9 12.8 1.1 1 0 0 1 1 1 0 Cdc42 effector TEX19 PF15553.1 CDJ62106.1 - 6.9 6.5 10.2 8.2 6.2 7.1 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Pex14_N PF04695.8 CDJ62106.1 - 7.9 6.5 24.6 14 5.7 17.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAF-1_p150 PF11600.3 CDJ62107.1 - 0.0089 15.4 37.9 0.0089 15.4 26.2 3.6 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 CDJ62107.1 - 0.059 12.7 39.4 0.066 12.5 17.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 CDJ62107.1 - 0.07 11.0 33.7 0.095 10.6 23.4 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 CDJ62107.1 - 3.7 7.5 41.0 2.9 7.8 3.4 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Helicase_C PF00271.26 CDJ62108.1 - 2.4e-28 97.8 0.0 2.4e-28 97.8 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CDJ62108.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Helicase C-terminal domain RAB3GAP2_N PF14655.1 CDJ62108.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Patatin PF01734.17 CDJ62109.1 - 0.055 13.3 0.4 0.055 13.3 0.2 3.4 3 0 0 3 3 3 0 Patatin-like phospholipase Band_3_cyto PF07565.8 CDJ62111.1 - 3 7.2 5.5 1.2 8.6 0.0 2.5 3 0 0 3 3 3 0 Band 3 cytoplasmic domain HECT PF00632.20 CDJ62112.1 - 4.2e-53 180.5 0.0 8.3e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CDJ62112.1 - 0.022 14.8 0.0 0.092 12.8 0.0 2.0 2 0 0 2 2 2 0 SPRY domain TRAM_LAG1_CLN8 PF03798.11 CDJ62113.1 - 7.4e-09 35.4 0.4 7.4e-09 35.4 0.3 2.5 3 0 0 3 3 3 2 TLC domain Helicase_C PF00271.26 CDJ62114.1 - 3.9e-10 39.4 0.0 2e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 CDJ62114.1 - 1.3e-09 37.9 0.0 1.3e-09 37.9 0.0 3.3 3 1 0 3 3 3 1 Helicase associated domain (HA2) AAA_22 PF13401.1 CDJ62114.1 - 0.029 14.5 0.0 6.5 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Borrelia_P83 PF05262.6 CDJ62114.1 - 1.9 6.6 30.5 0.026 12.8 15.7 1.8 2 0 0 2 2 2 0 Borrelia P83/100 protein HSP90 PF00183.13 CDJ62115.1 - 1.5e-78 264.4 0.0 1.2e-75 254.9 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CDJ62115.1 - 4e-13 49.2 0.0 7.1e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CDJ62115.1 - 1.2e-06 28.2 0.1 2.4e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DltD_M PF04918.7 CDJ62115.1 - 0.011 15.8 0.4 5.3 7.2 0.0 2.9 2 1 0 2 2 2 0 DltD central region DUF2183 PF09949.4 CDJ62115.1 - 0.024 14.5 0.1 3.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) DUF3800 PF12686.2 CDJ62115.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Methyltransf_15 PF09445.5 CDJ62116.1 - 1.5e-10 40.9 0.0 4.2e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CDJ62116.1 - 0.016 15.2 0.2 0.066 13.2 0.1 2.1 1 0 0 1 1 1 0 Methyltransferase domain BTV_NS2 PF04514.7 CDJ62117.1 - 0.1 11.4 1.7 0.14 10.9 1.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF966 PF06136.8 CDJ62117.1 - 3.6 6.9 12.1 4.5 6.5 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Med15 PF09606.5 CDJ62117.1 - 3.7 5.6 12.1 4.7 5.2 8.1 1.3 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TRSP PF12500.3 CDJ62117.1 - 5.5 6.4 9.0 3.6 7.0 0.4 2.7 1 1 1 2 2 2 0 TRSP domain C terminus to PRTase_2 RNA_pol_A_CTD PF03118.10 CDJ62118.1 - 0.00084 18.7 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain eIF-3_zeta PF05091.7 CDJ62118.1 - 5.6 5.4 17.7 4.6 5.7 0.6 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CTDII PF01556.13 CDJ62119.1 - 5.8e-21 74.1 0.0 2.5e-16 59.3 0.0 3.1 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CDJ62119.1 - 7.9e-15 54.3 0.1 5.5e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain DUF3435 PF11917.3 CDJ62119.1 - 4.2 5.9 8.6 1.1 7.9 3.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) TAF4 PF05236.9 CDJ62119.1 - 5.4 6.2 14.5 2.3 7.4 7.8 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family CDC27 PF09507.5 CDJ62120.1 - 0.13 11.5 15.1 0.13 11.4 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Filament_head PF04732.9 CDJ62120.1 - 1.1 9.9 8.8 0.2 12.3 1.8 2.1 1 1 1 2 2 2 0 Intermediate filament head (DNA binding) region DUF2365 PF10157.4 CDJ62120.1 - 1.3 8.9 4.6 12 5.7 0.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2365) P120R PF08062.6 CDJ62120.1 - 4.5 7.7 29.4 0.18 12.0 2.9 3.6 4 0 0 4 4 4 0 P120R (NUC006) repeat FUSC PF04632.7 CDJ62120.1 - 4.6 5.5 9.3 5 5.4 6.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Presenilin PF01080.12 CDJ62120.1 - 4.9 5.8 7.9 5.6 5.6 5.5 1.1 1 0 0 1 1 1 0 Presenilin LSM14 PF12701.2 CDJ62121.1 - 1.1e-29 102.0 0.0 1.1e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 Scd6-like Sm domain SM-ATX PF14438.1 CDJ62121.1 - 0.0028 17.5 0.7 0.0039 17.0 0.0 1.6 2 0 0 2 2 2 1 Ataxin 2 SM domain FDF PF09532.5 CDJ62121.1 - 0.71 10.4 7.6 0.2 12.2 0.4 2.4 2 0 0 2 2 2 0 FDF domain MSP1b PF03429.8 CDJ62121.1 - 1.5 6.6 8.0 2.3 6.0 5.6 1.1 1 0 0 1 1 1 0 Major surface protein 1B FCP1_C PF09309.5 CDJ62121.1 - 1.8 7.8 10.4 4.3 6.5 7.2 1.5 1 0 0 1 1 1 0 FCP1, C-terminal PAT1 PF09770.4 CDJ62121.1 - 2.3 6.3 14.1 2.9 5.9 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPV_E5 PF08135.6 CDJ62122.1 - 0.59 10.1 4.2 0.98 9.4 2.9 1.3 1 0 0 1 1 1 0 Major transforming protein E5 family DUF2228 PF10228.4 CDJ62123.1 - 0.044 13.3 0.2 0.044 13.3 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) zf-DHHC PF01529.15 CDJ62123.1 - 0.082 12.3 5.7 3.1 7.1 1.1 2.7 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF2722 PF10846.3 CDJ62123.1 - 0.43 9.5 23.4 0.23 10.4 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Gti1_Pac2 PF09729.4 CDJ62123.1 - 2.7 7.8 11.8 0.54 10.1 2.4 2.4 2 1 0 2 2 2 0 Gti1/Pac2 family Band_3_cyto PF07565.8 CDJ62123.1 - 2.9 7.3 16.5 0.83 9.1 4.2 2.6 3 0 0 3 3 3 0 Band 3 cytoplasmic domain Afi1 PF07792.7 CDJ62123.1 - 3 7.8 13.2 4.4 7.3 3.6 2.8 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking ABC2_membrane_2 PF12679.2 CDJ62123.1 - 9.3 5.0 6.5 1.5 7.6 0.4 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.27 CDJ62124.1 - 6.8e-17 60.6 1.4 1.3e-08 34.3 0.3 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Ribosomal_60s PF00428.14 CDJ62124.1 - 0.063 13.6 24.0 0.25 11.7 6.1 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3446 PF11928.3 CDJ62124.1 - 1.9 8.7 39.1 0.42 10.8 1.4 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3446) Nop25 PF09805.4 CDJ62129.1 - 3.3 7.7 11.0 4.6 7.3 7.6 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Kelch_4 PF13418.1 CDJ62130.1 - 8.6e-15 54.2 7.3 6.9e-05 22.5 0.0 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ62130.1 - 7.7e-14 51.2 2.8 6.7e-08 32.3 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CDJ62130.1 - 5.7e-10 38.9 0.8 1.8e-07 31.0 0.2 3.7 2 1 1 3 3 3 1 Kelch motif Kelch_1 PF01344.20 CDJ62130.1 - 3.3e-09 36.1 1.0 3.3e-09 36.1 0.7 3.5 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 CDJ62130.1 - 4.7e-09 35.6 0.8 0.00065 19.3 0.8 3.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 CDJ62130.1 - 0.00042 20.3 11.7 0.0021 18.1 0.1 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain YjcZ PF13990.1 CDJ62131.1 - 0.81 8.7 12.6 1.5 7.8 7.9 2.0 1 1 0 1 1 1 0 YjcZ-like protein Terminase_5 PF06056.7 CDJ62131.1 - 1.7 8.2 5.7 0.24 10.9 0.3 2.4 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) OmpH PF03938.9 CDJ62131.1 - 5.9 6.8 27.5 2.4 8.0 6.9 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ORF6C PF10552.4 CDJ62131.1 - 8.6 6.1 11.7 2.7 7.7 1.4 3.0 2 1 1 3 3 3 0 ORF6C domain FlxA PF14282.1 CDJ62131.1 - 9.7 6.1 13.8 1.2 9.0 5.8 2.3 2 1 1 3 3 3 0 FlxA-like protein SNAPc_SNAP43 PF09808.4 CDJ62133.1 - 0.027 14.1 3.1 0.045 13.4 0.0 2.3 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Spt20 PF12090.3 CDJ62133.1 - 0.067 12.5 2.2 0.62 9.3 0.9 2.3 2 0 0 2 2 2 0 Spt20 family Ribosomal_60s PF00428.14 CDJ62133.1 - 0.099 13.0 23.5 2 8.8 0.0 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Raftlin PF15250.1 CDJ62133.1 - 0.16 10.4 4.5 0.31 9.5 3.2 1.4 1 0 0 1 1 1 0 Raftlin Serinc PF03348.10 CDJ62133.1 - 1.3 7.6 3.9 0.46 9.1 0.7 1.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) Activator_LAG-3 PF11498.3 CDJ62133.1 - 3.2 6.4 25.2 0.64 8.7 12.2 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Gastrin PF00918.12 CDJ62133.1 - 8.5 7.2 13.0 0.6 10.9 3.6 2.9 3 0 0 3 3 3 0 Gastrin/cholecystokinin family HEM4 PF02602.10 CDJ62134.1 - 9.2e-09 34.8 33.7 6.2e-06 25.6 4.4 4.8 3 3 0 3 3 3 2 Uroporphyrinogen-III synthase HemD DUF2070 PF09843.4 CDJ62134.1 - 0.02 14.3 0.9 4.2 6.8 0.6 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) PAT1 PF09770.4 CDJ62134.1 - 2.5 6.2 43.1 0.097 10.8 18.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TruD PF01142.13 CDJ62135.1 - 1.1e-41 142.7 21.9 2e-20 72.8 0.5 5.4 5 0 0 5 5 5 3 tRNA pseudouridine synthase D (TruD) PAT1 PF09770.4 CDJ62135.1 - 0.0023 16.2 42.0 0.0023 16.2 29.1 6.3 5 2 0 5 5 5 1 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 CDJ62135.1 - 0.011 14.4 27.6 2.7 6.5 0.2 5.1 4 1 0 4 4 4 0 SIT4 phosphatase-associated protein PAT1 PF09770.4 CDJ62136.1 - 0.12 10.5 30.2 0.15 10.3 20.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ62136.1 - 0.17 11.7 28.1 0.23 11.3 19.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNase PF00565.12 CDJ62137.1 - 8.6e-52 173.9 0.2 1.9e-14 53.8 0.0 4.9 5 0 0 5 5 5 4 Staphylococcal nuclease homologue TUDOR PF00567.19 CDJ62137.1 - 0.055 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Tudor domain Dynamin_N PF00350.18 CDJ62141.1 - 1.1 9.1 7.4 0.089 12.6 1.1 2.0 2 0 0 2 2 2 0 Dynamin family Cellulose_synt PF03552.9 CDJ62141.1 - 5.3 5.2 5.9 8.5 4.5 4.1 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF3381 PF11861.3 CDJ62141.1 - 8.9 5.7 14.7 2 7.9 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) MOSP_C PF02722.10 CDJ62142.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal region TFIIA PF03153.8 CDJ62142.1 - 6.2 6.6 14.6 7.9 6.2 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 CDJ62142.1 - 7.8 5.3 9.5 0.51 9.2 2.9 1.5 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DNA_pol_delta_4 PF04081.8 CDJ62143.1 - 4e-15 56.1 0.0 5.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 zf-CCCH PF00642.19 CDJ62144.1 - 3.9e-05 23.2 0.5 0.00013 21.5 0.3 2.0 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Phostensin_N PF13916.1 CDJ62144.1 - 0.022 14.7 1.0 0.14 12.1 0.8 2.1 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Myb_Cef PF11831.3 CDJ62144.1 - 0.048 12.8 0.5 0.063 12.4 0.3 1.1 1 0 0 1 1 1 0 pre-mRNA splicing factor component FYVE PF01363.16 CDJ62144.1 - 0.12 12.3 9.0 0.049 13.5 3.8 2.3 2 1 0 2 2 2 0 FYVE zinc finger zf-CCCH_2 PF14608.1 CDJ62144.1 - 2 8.5 6.5 0.27 11.2 1.0 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type AAA PF00004.24 CDJ62145.1 - 2.8e-11 43.7 4.9 1.7e-06 28.2 0.2 3.7 2 1 1 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDJ62145.1 - 1.5e-06 28.3 1.7 0.003 17.6 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_11 PF13086.1 CDJ62145.1 - 0.0003 20.4 11.7 0.00045 19.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDJ62145.1 - 0.00054 19.6 2.7 0.00054 19.6 1.9 3.1 2 2 1 3 3 3 1 Part of AAA domain PhoH PF02562.11 CDJ62145.1 - 0.002 17.3 0.0 0.21 10.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 CDJ62145.1 - 0.0026 17.7 7.7 0.0026 17.7 5.3 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CDJ62145.1 - 0.003 17.2 0.7 0.012 15.3 0.0 2.3 2 1 1 3 3 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CDJ62145.1 - 0.004 16.5 0.0 0.004 16.5 0.0 2.4 3 1 1 4 4 2 1 IstB-like ATP binding protein BAF1_ABF1 PF04684.8 CDJ62145.1 - 0.0061 15.4 11.8 0.0061 15.4 8.2 4.5 3 2 1 4 4 1 1 BAF1 / ABF1 chromatin reorganising factor RuvB_N PF05496.7 CDJ62145.1 - 0.008 15.2 3.5 0.019 14.0 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 CDJ62145.1 - 0.012 15.0 0.0 0.099 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 CDJ62145.1 - 0.013 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.7 CDJ62145.1 - 0.015 13.9 0.1 0.015 13.9 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Mg_chelatase PF01078.16 CDJ62145.1 - 0.017 14.2 0.7 0.048 12.8 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CDJ62145.1 - 0.018 14.4 1.5 0.06 12.7 0.1 2.5 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 CDJ62145.1 - 0.026 14.7 0.4 0.063 13.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Bac_DnaA PF00308.13 CDJ62145.1 - 0.031 13.8 0.0 0.094 12.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial dnaA protein KAP_NTPase PF07693.9 CDJ62145.1 - 0.057 12.4 0.0 0.057 12.4 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.1 CDJ62145.1 - 0.068 13.0 0.0 1.6 8.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain Suf PF05843.9 CDJ62145.1 - 0.18 11.5 14.5 0.58 9.8 0.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) NACHT PF05729.7 CDJ62145.1 - 0.23 11.0 7.0 0.77 9.3 0.0 3.3 3 1 0 3 3 3 0 NACHT domain HlyD_2 PF12700.2 CDJ62145.1 - 0.29 10.2 5.0 0.19 10.8 0.4 2.0 2 0 0 2 2 2 0 HlyD family secretion protein ResIII PF04851.10 CDJ62145.1 - 0.3 10.8 8.0 0.092 12.5 0.8 2.7 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit OstA_C PF04453.9 CDJ62145.1 - 0.5 9.4 7.0 2.3 7.2 4.9 2.0 1 1 0 1 1 1 0 Organic solvent tolerance protein AAA_24 PF13479.1 CDJ62145.1 - 0.57 9.7 0.0 0.57 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain Rtf2 PF04641.7 CDJ62145.1 - 0.62 9.2 14.6 0.075 12.2 0.3 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3446 PF11928.3 CDJ62145.1 - 2.1 8.5 8.2 0.77 10.0 2.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) FAM60A PF15396.1 CDJ62145.1 - 3.6 7.2 7.0 33 4.1 0.0 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DDHD PF02862.12 CDJ62145.1 - 4.2 7.0 10.7 6.3 6.5 0.3 2.1 2 0 0 2 2 2 0 DDHD domain DUF775 PF05603.7 CDJ62145.1 - 4.5 6.7 17.9 1.1 8.6 4.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF775) AAA_2 PF07724.9 CDJ62145.1 - 6.4 6.6 0.0 6.4 6.6 0.0 3.9 3 2 0 4 4 3 0 AAA domain (Cdc48 subfamily) DUF605 PF04652.11 CDJ62145.1 - 6.4 6.0 22.9 0.95 8.7 3.9 2.1 2 0 0 2 2 2 0 Vta1 like PAT1 PF09770.4 CDJ62145.1 - 7.1 4.7 39.4 0.72 8.0 5.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ62145.1 - 9.6 6.4 20.1 29 4.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain DUF605 PF04652.11 CDJ62146.1 - 0.057 12.8 39.0 0.063 12.6 27.0 1.1 1 0 0 1 1 1 0 Vta1 like DDHD PF02862.12 CDJ62146.1 - 2.9 7.6 32.2 0.19 11.5 12.0 2.2 2 0 0 2 2 2 0 DDHD domain AAA PF00004.24 CDJ62147.1 - 1.9e-45 154.2 0.0 5.5e-45 152.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDJ62147.1 - 0.00028 20.0 0.0 0.00097 18.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CDJ62147.1 - 0.0029 16.3 0.0 0.005 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CDJ62147.1 - 0.0046 16.8 0.1 0.1 12.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CDJ62147.1 - 0.0085 15.8 0.0 0.05 13.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Dehydrin PF00257.14 CDJ62147.1 - 0.016 15.5 0.9 0.016 15.5 0.6 2.3 2 0 0 2 2 2 0 Dehydrin Med15 PF09606.5 CDJ62147.1 - 0.024 12.8 46.8 0.14 10.3 3.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_22 PF13401.1 CDJ62147.1 - 0.051 13.7 4.2 1.7 8.7 0.0 3.4 3 1 0 4 4 4 0 AAA domain AAA_16 PF13191.1 CDJ62147.1 - 0.089 12.7 0.0 0.089 12.7 0.0 4.7 3 2 1 4 4 3 0 AAA ATPase domain AAA_14 PF13173.1 CDJ62147.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain APC_CDC26 PF10471.4 CDJ62147.1 - 1.8 9.3 31.0 2 9.2 4.2 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF755 PF05501.6 CDJ62148.1 - 0.5 10.4 11.8 0.81 9.7 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AF-4 PF05110.8 CDJ62148.1 - 0.73 7.6 8.6 0.8 7.5 6.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Syntaphilin PF15290.1 CDJ62148.1 - 3.9 6.8 6.1 6 6.2 4.2 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Gar1 PF04410.9 CDJ62149.1 - 1.7e-16 60.0 4.6 1.7e-16 60.0 3.2 3.3 3 1 0 3 3 3 1 Gar1/Naf1 RNA binding region Ycf1 PF05758.7 CDJ62151.1 - 2.2 5.8 15.8 0.7 7.5 6.8 2.4 2 0 0 2 2 2 0 Ycf1 AP2 PF00847.15 CDJ62152.1 - 5.5e-08 32.8 0.2 5.5e-08 32.8 0.1 3.7 4 0 0 4 4 4 1 AP2 domain Ribosomal_L14 PF00238.14 CDJ62153.1 - 1.1e-16 60.7 0.0 1.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e OmpH PF03938.9 CDJ62155.1 - 1.3e-05 25.1 4.7 1.3e-05 25.1 3.3 4.5 2 2 0 2 2 2 1 Outer membrane protein (OmpH-like) Adaptin_binding PF10199.4 CDJ62155.1 - 6.2 7.1 0.0 6.2 7.1 0.0 6.0 2 2 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 MSP1_C PF07462.6 CDJ62156.1 - 2.6 6.3 10.5 4.4 5.5 7.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ATP-grasp_2 PF08442.5 CDJ62157.1 - 2.8e-57 193.3 3.0 7.4e-49 165.8 0.1 2.6 2 1 1 3 3 3 2 ATP-grasp domain Ligase_CoA PF00549.14 CDJ62157.1 - 1.8e-15 56.8 0.3 1.8e-15 56.8 0.2 2.6 3 0 0 3 3 3 1 CoA-ligase ATP-grasp_5 PF13549.1 CDJ62157.1 - 1.9e-08 33.7 0.7 4e-07 29.4 0.5 2.3 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CDJ62157.1 - 0.0054 16.2 1.1 0.092 12.2 0.0 2.5 1 1 1 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 CDJ62157.1 - 0.016 14.7 0.9 0.081 12.4 0.1 2.6 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CDJ62157.1 - 0.067 12.9 0.2 0.3 10.8 0.1 2.1 1 1 0 1 1 1 0 ATP-grasp domain DUF2562 PF10814.3 CDJ62157.1 - 4.1 7.3 14.6 7.7 6.4 1.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) SR-25 PF10500.4 CDJ62158.1 - 0.0032 16.9 25.1 0.0032 16.9 17.4 6.4 2 2 3 5 5 5 1 Nuclear RNA-splicing-associated protein YtxH PF12732.2 CDJ62158.1 - 0.077 13.3 0.5 0.077 13.3 0.4 4.8 5 1 0 5 5 5 0 YtxH-like protein DUF2228 PF10228.4 CDJ62158.1 - 8.4 5.8 12.6 0.016 14.7 1.5 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) Serglycin PF04360.7 CDJ62159.1 - 0.17 11.5 6.8 0.35 10.6 4.7 1.4 1 0 0 1 1 1 0 Serglycin TATR PF03430.8 CDJ62159.1 - 0.92 8.0 2.5 1.2 7.6 1.7 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator tRNA-synt_2 PF00152.15 CDJ62160.1 - 5e-77 258.9 0.5 5e-77 258.9 0.3 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CDJ62160.1 - 8.1e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CDJ62160.1 - 0.00031 19.9 0.2 0.22 10.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) CAF-1_p150 PF11600.3 CDJ62160.1 - 0.0015 17.9 20.4 0.0015 17.9 14.2 4.1 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDJ62160.1 - 0.012 13.8 49.8 0.024 12.8 23.9 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2802 PF10975.3 CDJ62160.1 - 0.015 14.9 4.6 0.015 14.9 3.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) DUF2997 PF11211.3 CDJ62160.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Hamartin PF04388.7 CDJ62160.1 - 0.6 8.7 24.4 0.96 8.0 16.9 1.2 1 0 0 1 1 1 0 Hamartin protein Spore_coat_CotO PF14153.1 CDJ62160.1 - 6.1 6.2 23.4 0.11 11.9 5.6 3.4 3 0 0 3 3 3 0 Spore coat protein CotO Cohesin_HEAT PF12765.2 CDJ62162.1 - 0.0011 18.8 2.4 0.038 13.9 0.1 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 CDJ62162.1 - 0.054 13.6 10.6 0.62 10.2 0.1 5.7 5 0 0 5 5 5 0 HEAT repeat TATR PF03430.8 CDJ62163.1 - 0.37 9.3 8.6 0.44 9.1 6.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator tRNA-synt_2 PF00152.15 CDJ62165.1 - 1.6e-74 250.7 0.0 2e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CDJ62165.1 - 1.1e-09 37.9 0.1 3.4e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CDJ62165.1 - 0.00024 20.3 0.1 0.002 17.3 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CDJ62165.1 - 0.0059 16.2 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) NUFIP2 PF15293.1 CDJ62166.1 - 0.19 10.3 8.5 0.28 9.8 5.9 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Macoilin PF09726.4 CDJ62166.1 - 4.8 5.3 7.5 6.4 4.9 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Ank_2 PF12796.2 CDJ62169.1 - 3.9e-09 36.7 2.1 1.2e-08 35.1 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ62169.1 - 4.1e-06 26.3 0.5 0.0036 17.0 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CDJ62169.1 - 1.4e-05 25.4 1.3 6.7e-05 23.2 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ62169.1 - 0.00033 20.6 0.1 0.055 13.7 0.0 3.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CDJ62169.1 - 0.0079 16.4 0.2 0.072 13.3 0.1 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF3731 PF12531.3 CDJ62169.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA-K related protein Methyltransf_26 PF13659.1 CDJ62169.1 - 0.61 10.1 3.7 2.2 8.3 0.5 2.8 2 2 0 2 2 2 0 Methyltransferase domain DENN PF02141.16 CDJ62171.1 - 6.6e-24 84.6 10.7 4.6e-20 72.1 5.4 2.7 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.13 CDJ62171.1 - 8.4e-05 22.4 4.4 0.0032 17.4 0.1 3.3 3 0 0 3 3 3 2 uDENN domain dDENN PF03455.14 CDJ62171.1 - 0.00013 21.9 0.0 0.00053 20.0 0.0 2.0 1 1 0 1 1 1 1 dDENN domain RRM_1 PF00076.17 CDJ62173.1 - 8.1e-16 57.4 0.1 1.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ62173.1 - 2.3e-14 53.0 0.0 3.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ62173.1 - 1.8e-09 37.2 0.3 3.9e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 CDJ62173.1 - 0.00029 19.2 92.8 0.00029 19.2 64.3 2.8 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal BRAP2 PF07576.7 CDJ62173.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 SET_assoc PF11767.3 CDJ62173.1 - 0.19 11.0 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated TFIIA PF03153.8 CDJ62173.1 - 1.9 8.3 56.2 0.46 10.3 35.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Methyltransf_11 PF08241.7 CDJ62174.1 - 2e-13 50.6 3.7 1.3e-12 48.0 0.1 2.8 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ62174.1 - 1e-09 38.6 0.2 3e-09 37.1 0.1 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ62174.1 - 1.7e-08 34.3 0.4 3.3e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ62174.1 - 1.7e-06 27.7 0.0 6.3e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ62174.1 - 2.8e-05 24.6 0.8 0.00091 19.7 0.5 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ62174.1 - 0.0001 22.7 0.0 0.0001 22.7 0.0 2.7 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ62174.1 - 0.003 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDJ62174.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 CDJ62174.1 - 0.075 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Crisp PF08562.5 CDJ62175.1 - 0.18 12.1 2.6 0.39 11.0 1.8 1.6 1 0 0 1 1 1 0 Crisp zf-DNL PF05180.7 CDJ62176.1 - 6.4e-28 96.2 0.5 1e-27 95.6 0.3 1.3 1 0 0 1 1 1 1 DNL zinc finger CGGC PF08821.6 CDJ62176.1 - 0.048 13.7 1.3 0.74 9.9 0.2 2.2 2 0 0 2 2 2 0 CGGC domain zf-CSL PF05207.8 CDJ62176.1 - 0.093 12.2 0.5 0.19 11.2 0.3 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF3458 PF11940.3 CDJ62177.1 - 1.8e-115 385.7 1.4 1.8e-115 385.7 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 CDJ62177.1 - 2.6e-61 207.8 0.0 3.6e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CDJ62177.1 - 3.1e-15 56.3 0.0 9.1e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily cNMP_binding PF00027.24 CDJ62179.1 - 8.8e-22 76.7 0.0 1.1e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Spc7 PF08317.6 CDJ62179.1 - 0.00088 18.0 14.6 0.00088 18.0 10.1 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein FliD_C PF07195.7 CDJ62179.1 - 0.27 10.4 6.0 0.14 11.4 0.4 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ClpS PF02617.12 CDJ62180.1 - 2.3e-14 52.8 0.2 3.7e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Pterin_bind PF00809.17 CDJ62181.1 - 1.7e-63 213.7 0.0 2.7e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 CDJ62181.1 - 7.9e-23 80.5 0.0 1.8e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF3560 PF12083.3 CDJ62181.1 - 0.052 13.6 0.2 0.76 9.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) CAP PF00188.21 CDJ62182.1 - 0.029 14.8 0.5 0.041 14.3 0.3 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Peptidase_A21 PF03566.8 CDJ62182.1 - 0.046 11.8 0.1 0.058 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family A21 Miff PF05644.6 CDJ62182.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff CAP PF00188.21 CDJ62183.1 - 0.0088 16.5 1.0 0.015 15.7 0.7 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DUF1485 PF07364.7 CDJ62183.1 - 0.046 12.9 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) Surface_antigen PF11054.3 CDJ62183.1 - 0.16 11.2 5.0 7.2 5.9 3.4 2.2 1 1 0 1 1 1 0 Sporozoite TA4 surface antigen CAP PF00188.21 CDJ62186.1 - 0.32 11.4 3.3 0.64 10.5 2.3 1.8 1 1 0 1 1 1 0 Cysteine-rich secretory protein family DUF3745 PF12560.3 CDJ62187.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3745) Death PF00531.17 CDJ62191.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Death domain SIP1 PF04938.7 CDJ62191.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) CAP PF00188.21 CDJ62193.1 - 0.039 14.4 0.7 0.084 13.3 0.4 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Surface_antigen PF11054.3 CDJ62194.1 - 0.0037 16.6 1.0 0.99 8.7 0.1 2.1 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen DUF3944 PF13099.1 CDJ62195.1 - 0.02 14.3 0.2 0.033 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) CAP PF00188.21 CDJ62195.1 - 0.045 14.2 1.3 0.068 13.6 0.9 1.4 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.21 CDJ62197.1 - 0.048 14.1 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Surface_antigen PF11054.3 CDJ62197.1 - 0.17 11.2 2.5 4.7 6.5 0.0 2.8 1 1 1 3 3 3 0 Sporozoite TA4 surface antigen tRNA-synt_1 PF00133.17 CDJ62200.1 - 2.7e-28 98.3 0.0 1.8e-06 26.2 0.0 4.8 3 2 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CDJ62200.1 - 1.9e-16 60.2 0.0 7.6e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CDJ62200.1 - 5.7e-16 58.1 0.0 8.8e-07 27.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CDJ62200.1 - 3.3e-09 36.2 0.0 8.5e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Tetraspannin PF00335.15 CDJ62201.1 - 3.3 6.9 13.6 1.6 7.9 7.7 1.7 1 1 1 2 2 2 0 Tetraspanin family FKBP_C PF00254.23 CDJ62202.1 - 8.3e-19 67.4 0.0 1.6e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Med15 PF09606.5 CDJ62202.1 - 0.004 15.4 55.7 0.044 12.0 9.2 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDJ62202.1 - 0.0051 15.7 6.5 0.0051 15.7 4.5 3.1 2 1 1 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor CAF-1_p150 PF11600.3 CDJ62202.1 - 0.0094 15.3 30.0 0.19 11.0 2.6 2.1 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_UL87 PF03043.9 CDJ62202.1 - 0.018 13.4 1.2 0.034 12.5 0.8 1.4 1 1 0 1 1 1 0 Herpesvirus UL87 family PAT1 PF09770.4 CDJ62202.1 - 0.33 9.1 48.4 0.072 11.3 18.5 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDJ62202.1 - 1.1 7.9 67.9 0.22 10.2 24.0 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DcuC PF03606.10 CDJ62202.1 - 2.2 6.4 5.0 0.27 9.4 0.1 1.8 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier TFIIA PF03153.8 CDJ62202.1 - 3.1 7.6 34.7 1.2 8.9 4.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 CDJ62203.1 - 0.0022 17.5 6.7 0.0025 17.3 4.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF789 PF05623.7 CDJ62203.1 - 0.26 10.7 7.8 0.31 10.4 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) DUF4045 PF13254.1 CDJ62203.1 - 0.8 8.9 13.8 0.83 8.8 9.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Suf PF05843.9 CDJ62203.1 - 1.2 8.8 22.3 1.4 8.6 15.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_LMP2 PF07415.6 CDJ62203.1 - 1.4 7.4 11.1 1.6 7.2 7.7 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein PAT1 PF09770.4 CDJ62203.1 - 1.8 6.7 41.5 2.2 6.4 28.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CKAP2_C PF15297.1 CDJ62203.1 - 2 7.1 15.5 2.6 6.7 10.7 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CDK5_activator PF03261.10 CDJ62203.1 - 2.2 7.5 12.9 2.6 7.2 8.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Spore_YhcN_YlaJ PF09580.5 CDJ62203.1 - 2.3 8.3 13.3 2.7 8.0 9.2 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BTV_NS2 PF04514.7 CDJ62203.1 - 2.4 6.9 9.5 2.7 6.8 6.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SAGA-Tad1 PF12767.2 CDJ62203.1 - 2.4 7.7 15.6 2.8 7.5 10.8 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Apt1 PF10351.4 CDJ62203.1 - 2.4 6.9 9.3 2.6 6.8 6.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PBP1_TM PF14812.1 CDJ62203.1 - 2.5 8.4 11.4 4.8 7.5 7.9 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF913 PF06025.7 CDJ62203.1 - 2.6 6.6 8.2 2.8 6.6 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFIIA PF03153.8 CDJ62203.1 - 2.7 7.7 32.7 3.3 7.5 22.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.1 CDJ62203.1 - 4.1 7.5 12.9 5.5 7.1 8.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nucleo_P87 PF07267.6 CDJ62203.1 - 5.2 5.6 13.5 5.9 5.4 9.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Med13_C PF06333.7 CDJ62203.1 - 6.2 5.2 12.9 7.1 5.0 9.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal GAGA_bind PF06217.7 CDJ62203.1 - 7.6 6.3 13.9 8.8 6.1 9.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SprA-related PF12118.3 CDJ62203.1 - 9.1 5.5 36.7 11 5.2 25.5 1.1 1 0 0 1 1 1 0 SprA-related family DHHW PF14286.1 CDJ62203.1 - 9.6 5.4 12.4 11 5.1 8.6 1.1 1 0 0 1 1 1 0 DHHW protein Cyto_heme_lyase PF01265.12 CDJ62203.1 - 9.7 5.6 14.3 14 5.1 9.9 1.3 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Tim54 PF11711.3 CDJ62203.1 - 9.7 4.6 13.0 11 4.4 9.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FLO_LFY PF01698.11 CDJ62203.1 - 9.9 4.8 14.2 12 4.6 9.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2580 PF10824.3 CDJ62205.1 - 1.9 8.8 10.8 0.15 12.4 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) IncA PF04156.9 CDJ62205.1 - 9.7 5.7 10.4 3.5 7.1 5.1 1.8 2 0 0 2 2 2 0 IncA protein Mpp10 PF04006.7 CDJ62206.1 - 6.2e-30 104.1 135.7 3e-21 75.4 5.7 5.0 3 1 2 5 5 5 3 Mpp10 protein DDHD PF02862.12 CDJ62208.1 - 4.1e-24 85.6 19.9 1.9e-17 63.8 0.0 4.4 2 1 1 3 3 3 2 DDHD domain AAA_29 PF13555.1 CDJ62209.1 - 0.0056 16.1 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CDJ62209.1 - 0.023 14.6 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 CDJ62209.1 - 0.025 15.0 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 CDJ62209.1 - 0.033 13.6 0.1 0.041 13.3 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CDJ62209.1 - 0.036 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CDJ62209.1 - 0.095 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 CDJ62209.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Myb_DNA-bind_5 PF13873.1 CDJ62212.1 - 0.49 10.3 4.3 1.5 8.7 0.5 3.2 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Sec8_exocyst PF04048.9 CDJ62212.1 - 0.71 9.5 10.6 3 7.4 0.0 3.5 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.7 CDJ62212.1 - 2.2 8.1 7.0 11 5.7 0.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SYF2 PF08231.7 CDJ62212.1 - 8.3 6.5 9.6 3.5 7.7 4.5 1.9 2 0 0 2 2 2 0 SYF2 splicing factor IF4E PF01652.13 CDJ62213.1 - 6.2e-13 48.6 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PS_Dcarbxylase PF02666.10 CDJ62216.1 - 6.8e-07 28.7 0.0 9.4e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Collagen PF01391.13 CDJ62218.1 - 0.003 17.0 14.1 0.003 17.0 9.8 3.3 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) AP2 PF00847.15 CDJ62218.1 - 0.047 13.8 0.7 0.047 13.8 0.5 2.3 3 0 0 3 3 3 0 AP2 domain DUF3273 PF11677.3 CDJ62220.1 - 9.3e-72 241.4 9.4 1.1e-71 241.1 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2849 PF11011.3 CDJ62221.1 - 0.098 12.9 0.2 0.098 12.9 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2849) Potyvirid-P3 PF13608.1 CDJ62223.1 - 0.0029 16.8 7.0 0.0036 16.4 4.8 1.3 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein SprA-related PF12118.3 CDJ62223.1 - 0.0083 15.4 26.5 0.012 14.9 18.4 1.2 1 0 0 1 1 1 1 SprA-related family RskA PF10099.4 CDJ62223.1 - 0.07 12.8 0.4 0.07 12.8 0.2 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TLC PF03219.9 CDJ62223.1 - 0.28 9.5 1.4 0.35 9.2 0.9 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter Suf PF05843.9 CDJ62223.1 - 0.51 10.0 9.8 0.62 9.7 6.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3801 PF12687.2 CDJ62223.1 - 1.8 8.0 10.5 3.3 7.2 7.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) DUF605 PF04652.11 CDJ62223.1 - 1.9 7.7 21.0 3.2 7.0 14.6 1.3 1 0 0 1 1 1 0 Vta1 like Conotoxin PF02950.12 CDJ62223.1 - 2.7 8.8 11.4 0.16 12.7 2.5 2.5 2 1 0 2 2 2 0 Conotoxin EphA2_TM PF14575.1 CDJ62223.1 - 2.9 8.3 5.1 1.9 8.9 1.9 1.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DivIC PF04977.10 CDJ62223.1 - 5.8 6.4 14.7 7.5 6.1 10.2 1.2 1 0 0 1 1 1 0 Septum formation initiator Ndc1_Nup PF09531.5 CDJ62225.1 - 3.6 5.8 9.2 6 5.1 6.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FUSC PF04632.7 CDJ62225.1 - 4.3 5.6 15.7 5.4 5.3 10.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TFIIF_alpha PF05793.7 CDJ62226.1 - 0.0013 17.1 17.3 0.0016 16.9 12.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SART-1 PF03343.8 CDJ62226.1 - 0.0057 15.0 15.7 0.0067 14.8 10.9 1.0 1 0 0 1 1 1 1 SART-1 family Cwf_Cwc_15 PF04889.7 CDJ62226.1 - 0.011 15.4 15.1 0.015 15.0 10.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Draxin PF15550.1 CDJ62226.1 - 0.015 14.9 7.8 0.018 14.7 5.4 1.3 1 0 0 1 1 1 0 Draxin DUF4603 PF15376.1 CDJ62226.1 - 0.033 11.4 13.2 0.036 11.2 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Macoilin PF09726.4 CDJ62226.1 - 0.097 10.9 21.6 0.12 10.6 15.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Dsh_C PF12316.3 CDJ62226.1 - 0.12 12.5 20.0 0.16 12.0 13.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2215 PF10225.4 CDJ62226.1 - 0.23 10.8 2.2 0.33 10.3 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF3807 PF12720.2 CDJ62226.1 - 0.35 11.0 18.8 2.2 8.3 11.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Vfa1 PF08432.5 CDJ62226.1 - 0.37 10.7 16.5 0.55 10.2 11.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SOBP PF15279.1 CDJ62226.1 - 0.38 11.1 9.3 0.48 10.7 6.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SRP-alpha_N PF04086.8 CDJ62226.1 - 0.47 9.7 20.0 0.61 9.4 13.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Band_3_cyto PF07565.8 CDJ62226.1 - 0.52 9.7 5.2 0.66 9.4 3.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1510 PF07423.6 CDJ62226.1 - 0.67 9.2 15.9 0.91 8.8 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 CDJ62226.1 - 0.85 9.0 19.2 1.3 8.4 13.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF572 PF04502.8 CDJ62226.1 - 0.87 8.7 19.9 1.2 8.3 13.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FLO_LFY PF01698.11 CDJ62226.1 - 0.96 8.2 12.2 1.5 7.5 8.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 CDJ62226.1 - 1 6.9 9.5 1.1 6.7 6.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 CDJ62226.1 - 1.1 8.2 12.6 1.4 7.9 8.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SR-25 PF10500.4 CDJ62226.1 - 1.4 8.3 55.3 4.5 6.6 37.7 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_pol_viral_N PF00242.12 CDJ62226.1 - 2.1 7.3 16.5 2.6 6.9 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SAPS PF04499.10 CDJ62226.1 - 2.2 6.8 9.9 3.3 6.2 6.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_polI_A34 PF08208.6 CDJ62226.1 - 2.4 7.7 28.2 3.6 7.2 19.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2217 PF10265.4 CDJ62226.1 - 2.7 6.6 20.8 3.5 6.2 14.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Neur_chan_memb PF02932.11 CDJ62226.1 - 4 7.2 9.3 5.2 6.8 6.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 CDJ62226.1 - 4.6 5.5 8.3 6.3 5.0 5.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF755 PF05501.6 CDJ62226.1 - 5.6 7.0 51.6 19 5.3 36.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Peptidase_S49_N PF08496.5 CDJ62226.1 - 9.2 6.0 11.8 19 5.0 8.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribosomal_60s PF00428.14 CDJ62227.1 - 0.0044 17.3 5.4 0.0044 17.3 3.7 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF4614 PF15391.1 CDJ62227.1 - 0.013 15.3 2.9 0.02 14.6 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) TFIIS_M PF07500.9 CDJ62229.1 - 2.2e-22 79.2 2.7 4.7e-22 78.2 0.0 2.4 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CDJ62229.1 - 5.3e-19 67.5 5.2 5.3e-19 67.5 3.6 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CDJ62229.1 - 2.8e-14 52.3 0.0 5e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.8 CDJ62229.1 - 0.022 14.4 0.4 0.048 13.3 0.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Baculo_LEF5_C PF11792.3 CDJ62229.1 - 0.089 12.1 0.3 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain XH PF03469.9 CDJ62229.1 - 0.18 11.4 2.6 1.8 8.2 0.9 2.2 2 0 0 2 2 2 0 XH domain Suf PF05843.9 CDJ62229.1 - 2.9 7.5 7.3 1.3 8.7 2.8 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CDC27 PF09507.5 CDJ62230.1 - 8.4 5.4 15.7 10 5.2 10.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1777 PF08648.7 CDJ62231.1 - 3.4e-24 85.5 61.3 7e-23 81.2 42.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDJ62231.1 - 1.4 7.2 26.5 1.7 7.0 18.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ndc1_Nup PF09531.5 CDJ62231.1 - 4.6 5.5 8.5 5.4 5.3 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Surface_antigen PF11054.3 CDJ62233.1 - 1.5e-98 329.2 2.4 1.7e-98 329.0 1.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62234.1 - 1.4e-87 293.3 1.0 1.5e-87 293.1 0.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62235.1 - 5e-97 324.2 2.0 5.7e-97 324.0 1.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3922 PF13059.1 CDJ62238.1 - 4.4 7.5 7.5 14 5.9 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3992) DUF2217 PF10265.4 CDJ62240.1 - 0.03 13.0 9.2 0.034 12.9 6.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CDJ62240.1 - 0.54 8.2 8.5 0.56 8.2 5.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF508 PF04370.7 CDJ62240.1 - 0.78 9.3 7.2 1.4 8.5 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Ribosomal_60s PF00428.14 CDJ62240.1 - 1.2 9.5 11.5 0.52 10.7 6.1 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Macoilin PF09726.4 CDJ62240.1 - 1.2 7.2 8.6 1.3 7.1 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Pap_E4 PF02711.9 CDJ62240.1 - 5.2 7.9 7.4 3.3 8.5 3.5 1.8 1 1 1 2 2 2 0 E4 protein APC_CDC26 PF10471.4 CDJ62240.1 - 6.6 7.5 7.4 2.8 8.7 3.3 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 rve PF00665.21 CDJ62243.1 - 5.4e-18 65.2 0.0 1.9e-17 63.4 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CDJ62243.1 - 2.8e-09 37.3 0.0 6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ62243.1 - 2.3e-07 30.5 0.0 1.2e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ62243.1 - 1.4e-06 28.2 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.19 CDJ62243.1 - 3.6e-06 26.5 0.0 7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 CDJ62243.1 - 5.2e-06 26.3 0.0 1.7e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 CDJ62243.1 - 0.00089 18.6 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 CDJ62243.1 - 0.016 14.6 1.9 0.031 13.6 1.3 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Spt20 PF12090.3 CDJ62245.1 - 0.057 12.7 4.2 1.7 7.9 0.8 2.1 2 0 0 2 2 2 0 Spt20 family Suf PF05843.9 CDJ62245.1 - 9.5 5.8 10.6 15 5.1 3.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.1 CDJ62245.1 - 9.8 5.0 10.5 11 4.8 2.5 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SprA-related PF12118.3 CDJ62246.1 - 0.017 14.4 31.6 0.022 14.1 21.9 1.2 1 0 0 1 1 1 0 SprA-related family DUF2722 PF10846.3 CDJ62246.1 - 0.019 14.0 20.9 0.02 13.9 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GAGA_bind PF06217.7 CDJ62246.1 - 0.067 13.1 15.0 0.082 12.8 10.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Utp14 PF04615.8 CDJ62246.1 - 0.11 10.5 14.7 0.13 10.3 10.2 1.0 1 0 0 1 1 1 0 Utp14 protein Herpes_TAF50 PF03326.8 CDJ62246.1 - 0.21 10.4 27.4 0.27 10.1 19.0 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PAT1 PF09770.4 CDJ62246.1 - 0.39 8.9 35.4 0.41 8.8 24.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OAR PF03826.12 CDJ62246.1 - 1 8.9 5.4 0.37 10.3 0.4 2.6 2 0 0 2 2 2 0 OAR domain Choline_kinase PF01633.15 CDJ62246.1 - 1.1 8.7 5.7 1.6 8.2 3.9 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2422 PF10337.4 CDJ62246.1 - 1.2 7.8 13.5 1.4 7.6 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FLO_LFY PF01698.11 CDJ62246.1 - 1.6 7.4 13.1 1.8 7.3 9.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 CDJ62246.1 - 3.7 7.8 10.3 4.7 7.4 7.2 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 CDJ62246.1 - 5.1 6.9 12.1 7.2 6.4 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDJ62246.1 - 5.5 6.7 12.6 7.6 6.2 8.7 1.3 1 0 0 1 1 1 0 DDHD domain Peptidase_S64 PF08192.6 CDJ62246.1 - 6.1 5.0 17.5 7.3 4.7 12.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Med15 PF09606.5 CDJ62246.1 - 6.5 4.8 52.7 7.5 4.6 36.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gag_spuma PF03276.9 CDJ62246.1 - 6.9 4.8 26.7 9.1 4.4 18.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein TRAPP PF04051.11 CDJ62248.1 - 7.5e-18 64.4 0.0 8.2e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF2633 PF11119.3 CDJ62248.1 - 0.045 13.4 0.2 8.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DUF755 PF05501.6 CDJ62249.1 - 0.00071 19.6 9.5 0.00071 19.6 6.6 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF755) AMP-binding PF00501.23 CDJ62249.1 - 0.33 9.2 2.7 0.38 9.0 0.1 2.0 2 0 0 2 2 2 0 AMP-binding enzyme G-alpha PF00503.15 CDJ62249.1 - 3.5 6.2 13.2 2.4 6.7 4.7 2.2 2 0 0 2 2 2 0 G-protein alpha subunit CagX PF03524.10 CDJ62249.1 - 5.4 6.2 17.1 1.1 8.4 0.3 3.2 3 0 0 3 3 3 0 Conjugal transfer protein GTP_EFTU PF00009.22 CDJ62250.1 - 1.7e-35 122.2 0.3 6e-35 120.3 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CDJ62250.1 - 4.4e-15 55.5 0.0 2.4e-10 40.2 0.0 3.3 3 0 0 3 3 3 2 Translation-initiation factor 2 MMR_HSR1 PF01926.18 CDJ62250.1 - 9.3e-07 28.8 0.1 2.4e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CDJ62250.1 - 9.9e-06 26.0 0.5 9.9e-06 26.0 0.4 2.7 3 0 0 3 3 3 1 Miro-like protein Ras PF00071.17 CDJ62250.1 - 3.5e-05 23.2 0.3 7e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 CDJ62250.1 - 0.00029 20.3 3.0 0.0021 17.5 2.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CDJ62250.1 - 0.00036 19.7 0.0 0.00076 18.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CDJ62250.1 - 0.001 18.9 5.2 0.011 15.5 0.1 3.5 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 CDJ62250.1 - 0.0041 16.3 0.3 0.0097 15.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CDJ62250.1 - 0.008 15.4 0.2 0.015 14.5 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 CDJ62250.1 - 0.032 13.2 0.2 0.088 11.8 0.1 1.7 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 CDJ62250.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.0 4 1 0 4 4 3 0 ABC transporter DUF4139 PF13598.1 CDJ62251.1 - 1.5 8.0 5.6 1.5 8.0 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) MelC1 PF06236.6 CDJ62251.1 - 6.8 6.7 14.5 10 6.1 10.0 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Ribosomal_L21p PF00829.16 CDJ62252.1 - 4.9e-16 58.6 0.0 7e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein YajC PF02699.10 CDJ62252.1 - 0.045 13.4 0.6 0.084 12.5 0.4 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Ank_2 PF12796.2 CDJ62254.1 - 1.3e-13 51.0 2.1 3.5e-06 27.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ62254.1 - 1.3e-09 37.3 5.8 0.043 13.6 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 CDJ62254.1 - 5.4e-07 29.9 0.3 1.6 9.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ62254.1 - 2.1e-06 27.3 0.3 2.7 8.5 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ribosomal_L38e PF01781.13 CDJ62255.1 - 3.8e-27 93.8 0.5 5.3e-27 93.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family RskA PF10099.4 CDJ62255.1 - 0.049 13.3 0.2 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Succ_CoA_lig PF13607.1 CDJ62255.1 - 0.1 12.1 1.0 0.15 11.7 0.7 1.2 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain SRR1 PF07985.7 CDJ62256.1 - 7.1e-11 41.8 0.2 1.6e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 SRR1 Collagen PF01391.13 CDJ62257.1 - 5.3e-07 29.0 30.4 5.3e-07 29.0 21.0 2.7 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) SLX9 PF15341.1 CDJ62258.1 - 0.57 10.6 6.3 0.85 10.0 0.2 2.6 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Pex14_N PF04695.8 CDJ62258.1 - 0.92 9.5 6.5 2.9 7.9 0.2 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-ZPR1 PF03367.8 CDJ62259.1 - 5e-59 198.0 5.5 1.9e-48 163.6 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn_Tnp_IS1595 PF12760.2 CDJ62259.1 - 0.0013 18.5 15.5 0.053 13.3 0.3 4.5 3 1 0 4 4 4 2 Transposase zinc-ribbon domain HypA PF01155.14 CDJ62259.1 - 0.059 13.0 9.3 1.2 8.8 3.0 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 CDJ62259.1 - 0.53 10.6 15.6 0.22 11.8 3.5 3.5 2 1 2 4 4 4 0 Restriction alleviation protein Lar zf-ISL3 PF14690.1 CDJ62259.1 - 0.67 10.0 14.1 7.5 6.6 0.2 4.2 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DSBA PF01323.15 CDJ62259.1 - 5 6.6 6.3 1.7 8.1 0.8 2.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain zinc_ribbon_2 PF13240.1 CDJ62259.1 - 6.2 6.4 25.1 1 8.9 2.0 4.5 4 0 0 4 4 4 0 zinc-ribbon domain TraT PF05818.7 CDJ62259.1 - 8.2 5.7 6.3 2.2 7.6 0.4 2.5 2 1 1 3 3 3 0 Enterobacterial TraT complement resistance protein Spt20 PF12090.3 CDJ62260.1 - 0.031 13.6 0.7 0.033 13.5 0.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF2489 PF10675.4 CDJ62260.1 - 2 8.0 9.4 3.1 7.4 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Med3 PF11593.3 CDJ62260.1 - 4.3 6.4 10.6 5.5 6.1 7.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Apolipoprotein PF01442.13 CDJ62261.1 - 0.00019 20.9 0.6 0.00024 20.6 0.1 1.4 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CDJ62261.1 - 0.029 14.7 3.5 0.077 13.3 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FlgN PF05130.7 CDJ62261.1 - 0.06 13.5 3.2 0.12 12.6 1.4 1.9 1 1 1 2 2 2 0 FlgN protein Exonuc_VII_L PF02601.10 CDJ62261.1 - 0.068 12.3 1.0 0.17 11.0 0.7 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Prominin PF05478.6 CDJ62261.1 - 0.075 10.5 0.0 0.11 10.0 0.0 1.2 1 0 0 1 1 1 0 Prominin ACCA PF03255.9 CDJ62261.1 - 0.098 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3708 PF12501.3 CDJ62261.1 - 4.1 7.2 9.1 1.6 8.5 0.3 2.3 1 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter Pkinase PF00069.20 CDJ62262.1 - 0.0045 16.1 0.0 0.012 14.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Sporozoite_P67 PF05642.6 CDJ62262.1 - 0.092 10.6 3.1 0.19 9.5 2.1 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Exo5 PF09810.4 CDJ62263.1 - 2e-35 122.5 2.9 1.2e-30 106.8 1.6 4.9 5 0 0 5 5 5 3 Exonuclease V - a 5' deoxyribonuclease DUF359 PF04019.7 CDJ62263.1 - 0.027 13.8 0.4 6.7 6.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF359) CD20 PF04103.10 CDJ62263.1 - 0.088 12.7 0.0 0.088 12.7 0.0 4.3 5 1 0 5 5 5 0 CD20-like family DUF3801 PF12687.2 CDJ62263.1 - 9.4 5.7 37.9 0.059 12.9 7.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) RRM_1 PF00076.17 CDJ62266.1 - 2.4e-15 55.8 0.0 2.7e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ62266.1 - 1.1e-12 47.7 0.0 1.2e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ62266.1 - 2.1e-09 37.1 0.0 2.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDJ62266.1 - 0.072 12.9 0.0 0.099 12.5 0.0 1.2 1 1 0 1 1 1 0 RNA binding motif Cpn60_TCP1 PF00118.19 CDJ62267.1 - 1.5e-75 254.7 0.0 1.9e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SR-25 PF10500.4 CDJ62267.1 - 0.0052 16.2 5.9 0.0052 16.2 4.1 2.6 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein PPP4R2 PF09184.6 CDJ62267.1 - 0.03 13.8 8.9 0.053 13.0 6.2 1.3 1 0 0 1 1 1 0 PPP4R2 Spt20 PF12090.3 CDJ62267.1 - 0.21 10.9 8.4 6.8 5.9 4.3 2.3 2 0 0 2 2 2 0 Spt20 family Suf PF05843.9 CDJ62267.1 - 0.44 10.2 13.3 5.4 6.6 5.5 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.3 CDJ62267.1 - 2.5 6.7 28.1 0.018 13.8 5.3 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RAB3GAP2_N PF14655.1 CDJ62267.1 - 7.2 5.4 10.8 11 4.8 3.2 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pkinase PF00069.20 CDJ62269.1 - 0.03 13.4 0.0 0.03 13.4 0.0 2.9 3 0 0 3 3 3 0 Protein kinase domain PcfK PF14058.1 CDJ62270.1 - 0.99 9.5 15.1 2 8.5 10.5 1.5 1 0 0 1 1 1 0 PcfK-like protein eIF-3_zeta PF05091.7 CDJ62270.1 - 1 7.9 19.0 1.2 7.6 13.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2201_N PF13203.1 CDJ62270.1 - 3 6.9 23.5 0.68 9.0 11.9 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Neur_chan_memb PF02932.11 CDJ62270.1 - 6.7 6.5 7.9 9.4 6.0 5.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDJ62270.1 - 8.5 3.9 14.9 11 3.5 10.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WBS_methylT PF12589.3 CDJ62271.1 - 4.9e-13 49.3 9.3 4.9e-13 49.3 6.4 2.4 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome K_channel_TID PF07941.6 CDJ62271.1 - 0.02 15.0 9.7 0.056 13.6 6.8 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s PF00428.14 CDJ62271.1 - 0.026 14.9 10.3 0.026 14.9 7.1 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein TCP PF03634.8 CDJ62271.1 - 0.96 9.8 7.4 0.061 13.7 0.9 2.0 2 0 0 2 2 2 0 TCP family transcription factor RRP14 PF15459.1 CDJ62271.1 - 2.6 8.1 0.0 2.6 8.1 0.0 3.1 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 Dehydrin PF00257.14 CDJ62272.1 - 0.0015 18.8 1.8 0.0015 18.8 1.2 2.2 2 0 0 2 2 2 1 Dehydrin DUF3357 PF11837.3 CDJ62272.1 - 0.015 15.1 1.7 0.015 15.1 1.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Glyco_hydro_63 PF03200.11 CDJ62272.1 - 0.82 7.4 3.6 1 7.0 2.5 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase FimP PF09766.4 CDJ62272.1 - 0.87 8.5 13.9 0.14 11.2 6.8 1.4 1 1 1 2 2 2 0 Fms-interacting protein MRP-S31 PF15433.1 CDJ62272.1 - 1 8.7 9.7 1.8 7.9 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Host_attach PF10116.4 CDJ62272.1 - 1.4 9.1 10.2 0.15 12.3 2.5 2.2 2 0 0 2 2 2 0 Protein required for attachment to host cells SR-25 PF10500.4 CDJ62272.1 - 1.9 7.9 36.5 0.087 12.2 3.7 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDJ62272.1 - 2.8 6.0 21.8 3.4 5.8 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Borrelia_P83 PF05262.6 CDJ62272.1 - 2.9 6.0 8.3 4.7 5.3 5.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF_4EBP PF05456.6 CDJ62272.1 - 4.7 6.9 7.1 1.7 8.3 2.7 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CbiA PF01656.18 CDJ62273.1 - 0.00012 21.5 0.2 0.00024 20.5 0.1 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.15 CDJ62273.1 - 0.00042 19.1 3.9 0.00057 18.6 2.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit DUF258 PF03193.11 CDJ62273.1 - 0.00074 18.7 0.2 0.0015 17.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArsA_ATPase PF02374.10 CDJ62273.1 - 0.0011 18.0 1.5 0.0011 18.0 1.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase IncA PF04156.9 CDJ62273.1 - 0.0054 16.3 5.2 0.0054 16.3 3.6 2.3 3 0 0 3 3 2 1 IncA protein DUF4094 PF13334.1 CDJ62273.1 - 0.008 16.5 3.5 0.069 13.5 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) NB-ARC PF00931.17 CDJ62273.1 - 0.0084 14.9 0.2 0.0084 14.9 0.1 1.5 2 0 0 2 2 2 1 NB-ARC domain Ribosomal_60s PF00428.14 CDJ62273.1 - 0.013 15.9 9.6 0.013 15.9 6.6 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA_25 PF13481.1 CDJ62273.1 - 0.019 14.3 1.7 0.02 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ParA PF10609.4 CDJ62273.1 - 0.022 14.6 0.1 0.053 13.4 0.0 1.8 2 0 0 2 2 1 0 ParA/MinD ATPase like UPF0079 PF02367.12 CDJ62273.1 - 0.026 14.1 0.2 0.055 13.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CDJ62273.1 - 0.03 15.1 0.7 0.047 14.5 0.5 1.3 1 0 0 1 1 1 0 AAA domain Herpes_DNAp_acc PF04929.7 CDJ62273.1 - 0.077 11.9 3.7 0.11 11.4 2.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SARG PF15385.1 CDJ62273.1 - 0.078 12.3 8.2 0.11 11.8 5.7 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein AAA_18 PF13238.1 CDJ62273.1 - 0.12 12.7 0.6 0.12 12.7 0.4 1.6 2 0 0 2 2 1 0 AAA domain Spt20 PF12090.3 CDJ62273.1 - 0.17 11.2 7.2 0.91 8.8 1.4 2.1 2 0 0 2 2 2 0 Spt20 family DUF3357 PF11837.3 CDJ62273.1 - 0.18 11.6 2.4 0.84 9.5 0.0 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF3357) T2SE PF00437.15 CDJ62273.1 - 0.19 10.6 1.6 0.25 10.1 1.1 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein Oleosin PF01277.12 CDJ62273.1 - 0.3 10.6 2.3 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 Oleosin EphA2_TM PF14575.1 CDJ62273.1 - 0.3 11.4 0.1 0.3 11.4 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Rad17 PF03215.10 CDJ62273.1 - 0.32 9.6 2.1 0.18 10.4 0.1 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Neur_chan_memb PF02932.11 CDJ62273.1 - 0.42 10.4 4.8 0.61 9.9 3.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_22 PF13401.1 CDJ62273.1 - 0.53 10.4 2.8 0.23 11.5 0.2 1.7 2 0 0 2 2 1 0 AAA domain FimP PF09766.4 CDJ62273.1 - 0.74 8.8 10.2 1.4 7.9 3.3 2.0 2 0 0 2 2 2 0 Fms-interacting protein PCYCGC PF13798.1 CDJ62273.1 - 0.99 9.0 5.2 0.21 11.2 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif DUF2681 PF10883.3 CDJ62273.1 - 1.2 9.3 15.5 4.4 7.5 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2489 PF10675.4 CDJ62273.1 - 1.4 8.6 16.5 0.097 12.3 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) RskA PF10099.4 CDJ62273.1 - 2.4 7.8 31.9 0.11 12.1 4.9 3.1 2 1 0 3 3 3 0 Anti-sigma-K factor rskA FCP1_C PF09309.5 CDJ62273.1 - 3.7 6.7 11.5 17 4.6 0.1 2.3 2 0 0 2 2 2 0 FCP1, C-terminal PAT1 PF09770.4 CDJ62273.1 - 4.4 5.4 20.6 5.9 5.0 14.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM154 PF15102.1 CDJ62273.1 - 5.9 6.5 6.7 1.4 8.6 1.7 2.0 2 0 0 2 2 2 0 TMEM154 protein family Shadoo PF14999.1 CDJ62273.1 - 9.1 6.1 34.3 3 7.7 3.3 3.2 2 1 0 3 3 3 0 Shadow of prion protein, neuroprotective Claudin_2 PF13903.1 CDJ62273.1 - 9.6 5.8 10.1 0.22 11.2 1.4 2.2 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction RAP1 PF07218.6 CDJ62274.1 - 2.5 6.0 14.3 5.1 5.0 9.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TSP_1 PF00090.14 CDJ62275.1 - 1e-17 63.9 37.8 1e-08 35.1 0.6 6.7 5 1 1 6 6 6 3 Thrombospondin type 1 domain Syndecan PF01034.15 CDJ62275.1 - 0.16 11.6 0.6 0.39 10.3 0.4 1.6 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.20 CDJ62276.1 - 2.5e-37 128.4 0.1 1.2e-34 119.6 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62276.1 - 1.2e-10 40.8 1.7 3.5e-08 32.8 0.6 3.3 2 1 0 2 2 2 1 Protein tyrosine kinase PAN_1 PF00024.21 CDJ62276.1 - 2.9e-05 23.7 4.7 0.029 14.1 0.1 3.0 3 0 0 3 3 3 2 PAN domain PAN_3 PF08277.7 CDJ62276.1 - 0.0053 16.3 0.1 4.6 6.9 0.0 2.5 2 0 0 2 2 2 2 PAN-like domain PAN_4 PF14295.1 CDJ62276.1 - 0.012 15.2 6.3 0.099 12.3 0.0 2.9 2 1 0 2 2 2 0 PAN domain RNA_lig_T4_1 PF09511.5 CDJ62276.1 - 9.5 5.6 7.7 0.99 8.8 0.6 2.2 2 0 0 2 2 2 0 RNA ligase PAT1 PF09770.4 CDJ62277.1 - 0.00019 19.8 20.7 0.00019 19.8 14.3 1.5 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Peptidase_S49_N PF08496.5 CDJ62277.1 - 0.043 13.5 6.8 0.54 10.0 2.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-DHHC PF01529.15 CDJ62277.1 - 0.075 12.4 0.1 0.074 12.4 0.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Serinc PF03348.10 CDJ62277.1 - 0.4 9.3 7.6 0.58 8.8 5.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) FimP PF09766.4 CDJ62277.1 - 2 7.3 22.1 2.9 6.8 15.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF1980 PF09323.5 CDJ62277.1 - 2.6 7.7 6.2 1.5 8.5 3.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF4544 PF15077.1 CDJ62277.1 - 3.3 7.1 5.9 4.5 6.6 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) DEAD PF00270.24 CDJ62278.1 - 4.1e-29 101.2 4.5 4.1e-29 101.2 3.1 3.7 2 1 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ62278.1 - 2.3e-21 75.4 0.0 2.3e-21 75.4 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Vps39_1 PF10366.4 CDJ62278.1 - 0.0016 18.4 0.2 0.0016 18.4 0.1 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 K_channel_TID PF07941.6 CDJ62278.1 - 0.014 15.6 2.9 0.014 15.6 2.0 8.7 4 3 3 7 7 7 0 Potassium channel Kv1.4 tandem inactivation domain tRNA-synt_1b PF00579.20 CDJ62279.1 - 4.5e-35 121.2 0.1 6.8e-27 94.3 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) DUF3446 PF11928.3 CDJ62279.1 - 0.013 15.6 11.4 0.26 11.4 3.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF1117 PF06547.7 CDJ62279.1 - 1.9 8.6 7.6 13 5.9 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1117) Peptidase_M75 PF09375.5 CDJ62280.1 - 0.063 12.5 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Imelysin O-antigen_lig PF13425.1 CDJ62281.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Rhomboid PF01694.17 CDJ62281.1 - 0.15 12.1 0.9 0.27 11.2 0.6 1.4 1 0 0 1 1 1 0 Rhomboid family RRS1 PF04939.7 CDJ62282.1 - 1.5e-30 105.8 7.8 1.5e-28 99.3 5.4 2.2 1 1 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) QRPTase_C PF01729.14 CDJ62282.1 - 0.46 10.0 4.0 0.28 10.7 1.6 1.5 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain CLP_protease PF00574.18 CDJ62282.1 - 0.73 9.4 4.4 1.4 8.5 3.1 1.5 1 0 0 1 1 1 0 Clp protease Macoilin PF09726.4 CDJ62282.1 - 8 4.5 8.8 11 4.1 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Med15 PF09606.5 CDJ62283.1 - 7.4e-05 21.1 34.0 9.7e-05 20.7 23.6 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3801 PF12687.2 CDJ62283.1 - 0.002 17.7 9.7 0.0037 16.8 6.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) NTP_transf_3 PF12804.2 CDJ62283.1 - 0.0055 16.7 6.8 0.01 15.8 4.7 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fmp27_WPPW PF10359.4 CDJ62283.1 - 0.1 10.9 17.9 0.017 13.5 8.2 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain FimP PF09766.4 CDJ62283.1 - 0.32 10.0 23.1 1.4 7.9 7.2 2.2 2 0 0 2 2 2 0 Fms-interacting protein zf-DHHC PF01529.15 CDJ62283.1 - 0.37 10.1 2.1 1.5 8.2 0.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Plasmodium_Vir PF05795.6 CDJ62283.1 - 0.55 9.3 7.5 0.32 10.1 0.7 2.7 3 0 0 3 3 3 0 Plasmodium vivax Vir protein FlaG PF03646.10 CDJ62283.1 - 0.57 10.3 26.7 0.5 10.5 8.7 3.2 3 0 0 3 3 3 0 FlaG protein ARD PF03079.9 CDJ62283.1 - 0.78 9.6 6.7 0.3 11.0 2.2 1.8 2 0 0 2 2 2 0 ARD/ARD' family DUF4220 PF13968.1 CDJ62283.1 - 1.8 7.5 5.9 2.9 6.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Peptidase_S49_N PF08496.5 CDJ62283.1 - 2.1 8.1 12.8 3.9 7.2 3.9 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_S64 PF08192.6 CDJ62283.1 - 4.6 5.4 15.8 8.9 4.5 11.0 1.4 1 0 0 1 1 1 0 Peptidase family S64 NusB PF01029.13 CDJ62283.1 - 5.2 7.0 7.7 0.69 9.9 1.8 2.0 2 0 0 2 2 2 0 NusB family DUF912 PF06024.7 CDJ62283.1 - 5.2 7.1 7.8 28 4.8 2.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4557 PF15101.1 CDJ62283.1 - 5.8 6.7 21.2 2.4 7.9 6.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Bud13 PF09736.4 CDJ62283.1 - 7.3 6.8 21.2 3.1 8.0 6.6 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex CDK2AP PF09806.4 CDJ62283.1 - 7.9 6.6 46.3 0.3 11.3 1.1 4.3 4 0 0 4 4 4 0 Cyclin-dependent kinase 2-associated protein Wx5_PLAF3D7 PF09688.5 CDJ62283.1 - 8.1 6.4 10.0 0.7 9.8 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) DDRGK PF09756.4 CDJ62283.1 - 8.9 5.6 27.0 0.32 10.3 8.2 2.2 2 0 0 2 2 2 0 DDRGK domain MORN PF02493.15 CDJ62284.1 - 7e-05 22.3 1.5 7e-05 22.3 1.0 2.7 3 0 0 3 3 3 1 MORN repeat PGA2 PF07543.7 CDJ62284.1 - 0.043 13.6 4.8 0.074 12.8 3.3 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 NST1 PF13945.1 CDJ62284.1 - 0.057 13.4 9.5 0.075 13.1 6.6 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator ETRAMP PF09716.5 CDJ62284.1 - 0.12 12.3 0.4 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TFIIA PF03153.8 CDJ62284.1 - 1.2 8.9 14.8 1.9 8.3 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.3 CDJ62284.1 - 3.7 6.0 8.7 4.9 5.6 6.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF566 PF04484.7 CDJ62284.1 - 8.8 5.7 15.2 11 5.3 10.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF912 PF06024.7 CDJ62285.1 - 0.00036 20.5 0.4 0.0004 20.3 0.3 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex14_N PF04695.8 CDJ62285.1 - 0.00072 19.6 2.8 0.00072 19.6 2.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BatD PF13584.1 CDJ62285.1 - 0.0017 17.0 0.7 0.0017 17.0 0.5 1.0 1 0 0 1 1 1 1 Oxygen tolerance DcuC PF03606.10 CDJ62285.1 - 0.0032 15.7 0.2 0.0034 15.6 0.1 1.0 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier DUF2077 PF09850.4 CDJ62285.1 - 0.0032 16.8 0.1 0.0035 16.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2077) DUF4064 PF13273.1 CDJ62285.1 - 0.0047 17.0 0.2 0.0047 17.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Consortin_C PF15281.1 CDJ62285.1 - 0.0062 16.0 0.9 0.0071 15.8 0.6 1.0 1 0 0 1 1 1 1 Consortin C-terminus DUF3899 PF13038.1 CDJ62285.1 - 0.0064 16.6 0.1 0.0067 16.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) CD20 PF04103.10 CDJ62285.1 - 0.0076 16.1 1.6 0.0076 16.1 1.1 1.0 1 0 0 1 1 1 1 CD20-like family DUF2207 PF09972.4 CDJ62285.1 - 0.0087 14.6 0.2 0.0087 14.6 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) T2SF PF00482.18 CDJ62285.1 - 0.013 15.4 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Peroxin-13_N PF04088.8 CDJ62285.1 - 0.025 14.5 0.5 0.026 14.4 0.3 1.0 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF3357 PF11837.3 CDJ62285.1 - 0.029 14.2 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4366 PF14283.1 CDJ62285.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Viral_Beta_CD PF04530.7 CDJ62285.1 - 0.038 14.1 0.2 0.038 14.1 0.1 1.0 1 0 0 1 1 1 0 Viral Beta C/D like family Anoctamin PF04547.7 CDJ62285.1 - 0.066 11.8 0.2 0.067 11.8 0.1 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF3619 PF12279.3 CDJ62285.1 - 0.068 13.2 0.8 0.067 13.2 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Glt_symporter PF03616.9 CDJ62285.1 - 0.077 11.4 0.3 0.078 11.4 0.2 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF4175 PF13779.1 CDJ62285.1 - 0.087 10.5 13.8 0.081 10.6 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ETRAMP PF09716.5 CDJ62285.1 - 0.099 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Cir_Bir_Yir PF06022.6 CDJ62285.1 - 0.1 11.7 0.4 0.11 11.7 0.3 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir DUF3675 PF12428.3 CDJ62285.1 - 0.11 12.7 1.0 0.13 12.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) UPF0233 PF06781.7 CDJ62285.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Scs3p PF10261.4 CDJ62285.1 - 0.13 11.2 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Prion PF00377.13 CDJ62285.1 - 0.13 11.9 1.8 0.15 11.7 1.2 1.3 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain TraG_N PF07916.6 CDJ62285.1 - 0.14 10.5 4.6 0.14 10.6 3.2 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TOM13 PF08219.6 CDJ62285.1 - 0.16 11.7 0.3 0.16 11.7 0.2 1.1 1 0 0 1 1 1 0 Outer membrane protein TOM13 MFS_Mycoplasma PF07672.8 CDJ62285.1 - 0.17 11.0 0.4 0.17 11.0 0.2 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter TLV_coat PF00429.14 CDJ62285.1 - 0.18 10.2 5.4 0.19 10.1 3.7 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) OATP PF03137.15 CDJ62285.1 - 0.19 9.7 3.1 0.19 9.7 2.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family 7TM_GPCR_Srv PF10323.4 CDJ62285.1 - 0.25 10.4 2.0 0.22 10.5 1.4 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv 60KD_IMP PF02096.15 CDJ62285.1 - 0.31 10.6 9.6 0.32 10.6 6.6 1.0 1 0 0 1 1 1 0 60Kd inner membrane protein DUF2232 PF09991.4 CDJ62285.1 - 0.5 9.3 5.4 0.52 9.2 3.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FimP PF09766.4 CDJ62285.1 - 0.59 9.1 12.0 0.61 9.1 8.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF2722 PF10846.3 CDJ62285.1 - 0.72 8.8 14.3 0.79 8.6 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.9 CDJ62285.1 - 0.78 9.4 8.3 0.74 9.4 5.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ62285.1 - 1.7 7.9 9.9 1.9 7.7 6.8 1.1 1 0 0 1 1 1 0 Spt20 family FCP1_C PF09309.5 CDJ62285.1 - 2.9 7.1 9.6 3.2 6.9 6.7 1.0 1 0 0 1 1 1 0 FCP1, C-terminal RAB3GAP2_N PF14655.1 CDJ62285.1 - 2.9 6.7 8.5 3 6.7 5.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2489 PF10675.4 CDJ62285.1 - 3.6 7.2 11.0 3.9 7.1 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Med3 PF11593.3 CDJ62285.1 - 8.1 5.5 16.5 7.5 5.6 11.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Lyase_1 PF00206.15 CDJ62286.1 - 2.2e-06 27.1 0.0 2.5e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Lyase FAST_2 PF08368.7 CDJ62286.1 - 0.0069 16.7 0.7 0.028 14.7 0.1 2.0 1 1 1 2 2 2 1 FAST kinase-like protein, subdomain 2 UPF0158 PF03682.8 CDJ62286.1 - 0.023 14.3 2.7 0.02 14.4 0.9 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0158) HisKA_2 PF07568.7 CDJ62286.1 - 0.091 12.6 0.6 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 Histidine kinase Med26 PF08711.6 CDJ62288.1 - 1.9e-10 40.0 0.1 3.5e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TATR PF03430.8 CDJ62288.1 - 0.15 10.6 11.1 0.16 10.5 3.9 2.0 2 0 0 2 2 2 0 Trans-activating transcriptional regulator SOBP PF15279.1 CDJ62288.1 - 1.7 8.9 12.0 5.7 7.2 1.7 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein GAGA_bind PF06217.7 CDJ62288.1 - 2.9 7.7 17.6 0.75 9.7 6.6 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Zip PF02535.17 CDJ62288.1 - 5 6.0 12.2 1.8 7.4 6.8 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter SelP_N PF04592.9 CDJ62288.1 - 9.3 5.5 17.7 0.14 11.5 6.8 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region WES_acyltransf PF03007.11 CDJ62289.1 - 7.7e-07 28.9 11.4 0.0004 20.0 0.9 3.2 3 0 0 3 3 3 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 CDJ62289.1 - 2.6e-06 27.3 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) DUF1049 PF06305.6 CDJ62289.1 - 0.0041 16.5 3.0 0.0041 16.5 2.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) SpoIIIAH PF12685.2 CDJ62289.1 - 0.28 10.6 0.0 0.28 10.6 0.0 1.8 2 1 0 2 2 2 0 SpoIIIAH-like protein DUF788 PF05620.6 CDJ62289.1 - 1.5 8.6 2.8 4.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF788) HSP70 PF00012.15 CDJ62290.1 - 8.7e-264 876.0 11.3 1e-263 875.7 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CDJ62290.1 - 1.6e-20 72.9 2.0 1.5e-19 69.7 0.6 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CDJ62290.1 - 0.0036 17.1 1.4 2.1 8.2 0.0 3.7 2 1 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.11 CDJ62290.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CDJ62290.1 - 0.011 14.5 0.3 1.7 7.4 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF4582 PF15189.1 CDJ62290.1 - 0.057 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Hydantoinase_A PF01968.13 CDJ62290.1 - 0.073 12.1 0.1 0.073 12.1 0.1 2.5 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase DUF4500 PF14937.1 CDJ62290.1 - 0.14 11.9 0.1 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) MACPF PF01823.14 CDJ62291.1 - 3.3e-33 115.1 0.3 5.6e-33 114.4 0.0 1.6 2 0 0 2 2 2 1 MAC/Perforin domain Ribosomal_60s PF00428.14 CDJ62292.1 - 4.9 7.6 34.5 2.4 8.6 6.5 4.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein MelC1 PF06236.6 CDJ62293.1 - 1 9.3 7.3 1.3 8.9 5.0 1.1 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 CTP_transf_2 PF01467.21 CDJ62294.1 - 1.6e-27 96.5 0.0 3.6e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CDJ62294.1 - 0.0058 16.2 0.6 0.67 9.5 0.0 2.5 2 0 0 2 2 2 2 FAD synthetase Ribosomal_60s PF00428.14 CDJ62294.1 - 0.027 14.8 0.8 0.027 14.8 0.5 6.8 6 0 0 6 6 6 0 60s Acidic ribosomal protein Pkinase PF00069.20 CDJ62295.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain rve PF00665.21 CDJ62296.1 - 1.2e-10 41.5 0.0 4.1e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDJ62296.1 - 4.9e-08 32.5 0.0 1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDJ62296.1 - 0.00069 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDJ62298.1 - 3.1e-13 49.1 0.0 4.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PIG-U PF06728.8 CDJ62299.1 - 2.4e-42 145.1 2.7 4.7e-42 144.2 1.9 1.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U SprA-related PF12118.3 CDJ62299.1 - 0.00054 19.3 12.5 0.00054 19.3 8.7 3.2 3 0 0 3 3 3 1 SprA-related family EPL1 PF10513.4 CDJ62299.1 - 0.069 13.3 9.1 0.84 9.8 2.5 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like AIF_C PF14721.1 CDJ62299.1 - 0.23 11.7 10.0 0.71 10.1 0.1 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Exonuc_VII_L PF02601.10 CDJ62299.1 - 0.26 10.4 12.6 0.43 9.7 8.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Endonuc_Holl PF10107.4 CDJ62299.1 - 0.56 9.8 11.9 0.24 11.0 3.3 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Plasmodium_Vir PF05795.6 CDJ62299.1 - 1.7 7.7 2.9 1.5 7.9 0.1 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF4557 PF15101.1 CDJ62299.1 - 3.6 7.3 24.3 6.3 6.5 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) RR_TM4-6 PF06459.7 CDJ62299.1 - 8.9 6.1 14.3 0.79 9.5 2.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MMR1 PF08505.5 CDJ62299.1 - 9.8 6.1 20.8 4.7 7.1 1.3 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Sec62 PF03839.11 CDJ62302.1 - 2.4e-23 82.7 33.0 5.3e-16 58.7 12.2 2.5 2 1 1 3 3 3 2 Translocation protein Sec62 OPT PF03169.10 CDJ62302.1 - 0.63 8.3 25.5 0.19 10.0 1.6 2.2 2 0 0 2 2 2 0 OPT oligopeptide transporter protein PsbI PF02532.9 CDJ62303.1 - 0.015 14.9 0.9 0.03 13.9 0.6 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF2600 PF10776.4 CDJ62304.1 - 0.13 11.0 0.1 0.71 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) SidE PF12252.3 CDJ62305.1 - 0.006 13.9 3.9 0.0079 13.5 2.7 1.1 1 0 0 1 1 1 1 Dot/Icm substrate protein Asp_protease_2 PF13650.1 CDJ62306.1 - 1.3e-11 44.8 0.0 2.4e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ62306.1 - 5e-09 35.8 0.0 1.4e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ62306.1 - 7e-08 32.3 0.0 2.1e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ62306.1 - 3.3e-06 27.0 0.0 6.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ62306.1 - 0.00042 19.8 0.0 0.0034 16.9 0.0 2.3 3 0 0 3 3 3 1 Aspartyl protease Retrotrans_gag PF03732.12 CDJ62306.1 - 0.0024 17.9 0.2 0.0067 16.4 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF3552 PF12072.3 CDJ62306.1 - 0.11 11.6 0.6 0.22 10.7 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Peptidase_A2B PF12384.3 CDJ62306.1 - 0.18 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase rve PF00665.21 CDJ62307.1 - 1.9e-20 73.1 0.0 3.3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDJ62307.1 - 1e-12 47.8 0.0 3.1e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDJ62307.1 - 3.1e-07 29.9 0.0 6.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 CDJ62307.1 - 0.037 13.5 0.2 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain PHY PF00360.15 CDJ62307.1 - 0.11 11.5 0.1 24 3.9 0.0 2.9 3 0 0 3 3 3 0 Phytochrome region zf-CCCH PF00642.19 CDJ62308.1 - 1.8e-09 37.0 14.6 1.5e-05 24.5 2.0 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Hist_deacetyl PF00850.14 CDJ62309.1 - 7.8e-61 206.0 0.1 1.7e-60 204.9 0.1 1.6 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.2 CDJ62309.1 - 5.6e-13 49.0 0.2 6.8e-09 35.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDJ62309.1 - 1.3e-09 38.0 3.1 4.8e-08 32.9 0.3 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDJ62309.1 - 6.3e-09 36.1 5.8 0.0014 19.0 0.3 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CDJ62309.1 - 1.8e-08 33.7 13.0 3.3e-06 26.6 0.3 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CDJ62309.1 - 4.2e-06 26.4 2.1 0.062 13.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat DDRGK PF09756.4 CDJ62310.1 - 5.7e-42 143.2 13.6 5.7e-42 143.2 9.4 2.5 2 1 1 3 3 3 1 DDRGK domain Peptidase_S64 PF08192.6 CDJ62310.1 - 0.13 10.5 6.9 0.17 10.1 4.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 CAF-1_p150 PF11600.3 CDJ62310.1 - 0.81 9.0 38.0 0.087 12.1 22.8 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RskA PF10099.4 CDJ62310.1 - 1.1 8.9 15.6 6 6.5 8.2 2.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Med3 PF11593.3 CDJ62310.1 - 1.5 7.9 8.5 2.3 7.3 5.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2782 PF11191.3 CDJ62310.1 - 4.2 7.3 5.9 4.6 7.2 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2782) Hid1 PF12722.2 CDJ62310.1 - 4.6 4.7 8.0 5.8 4.4 5.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Abhydrolase_6 PF12697.2 CDJ62311.1 - 0.015 15.1 9.1 0.14 11.9 5.4 2.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family 14-3-3 PF00244.15 CDJ62312.1 - 0.024 13.7 0.5 2.2 7.3 0.0 2.5 2 0 0 2 2 2 0 14-3-3 protein NARP1 PF12569.3 CDJ62312.1 - 0.061 12.0 0.1 0.16 10.7 0.1 1.6 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SRP40_C PF05022.7 CDJ62314.1 - 8.7e-24 83.8 0.8 8.7e-24 83.8 0.6 2.1 2 0 0 2 2 2 1 SRP40, C-terminal domain RNA_pol_Rpb1_1 PF04997.7 CDJ62314.1 - 2.4 7.3 9.3 3.7 6.7 6.4 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Ndc1_Nup PF09531.5 CDJ62314.1 - 7.3 4.8 9.6 8.5 4.6 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pap_E4 PF02711.9 CDJ62314.1 - 9.3 7.1 7.7 2.2 9.1 0.5 2.4 1 1 1 2 2 2 0 E4 protein SR-25 PF10500.4 CDJ62316.1 - 0.0031 17.0 6.8 0.0044 16.5 4.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.4 CDJ62316.1 - 0.011 15.4 6.3 0.022 14.5 2.4 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF755 PF05501.6 CDJ62316.1 - 0.21 11.6 13.2 0.39 10.7 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) APC_CDC26 PF10471.4 CDJ62316.1 - 0.39 11.4 7.0 0.66 10.7 4.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Ribosomal_60s PF00428.14 CDJ62316.1 - 0.83 10.0 6.3 0.087 13.2 1.2 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1635 PF07795.6 CDJ62316.1 - 0.89 8.8 6.5 1.2 8.4 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF1631 PF07793.6 CDJ62316.1 - 0.9 7.5 6.2 1 7.4 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Myco_19_kDa PF05481.7 CDJ62316.1 - 1.9 8.3 6.0 22 4.8 2.6 2.3 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen AAA_23 PF13476.1 CDJ62317.1 - 0.21 11.9 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1777 PF08648.7 CDJ62318.1 - 0.74 9.5 21.9 1.1 9.0 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Parvo_coat PF00740.13 CDJ62318.1 - 1.1 8.0 32.3 1.3 7.8 22.4 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Med15 PF09606.5 CDJ62318.1 - 3.1 5.9 91.6 3.6 5.6 63.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dapper PF15268.1 CDJ62318.1 - 5.3 5.7 38.9 6.1 5.5 27.0 1.0 1 0 0 1 1 1 0 Dapper PAT1 PF09770.4 CDJ62318.1 - 5.7 5.0 74.9 6.9 4.7 51.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.1 CDJ62318.1 - 9.3 5.4 26.7 14 4.7 18.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) WD40 PF00400.27 CDJ62319.1 - 1.3e-10 40.6 7.7 2.8e-06 26.9 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 CDJ62321.1 - 1.8e-44 148.1 19.1 1.1e-09 37.7 0.0 8.8 8 2 0 8 8 8 8 WD domain, G-beta repeat Hira PF07569.6 CDJ62321.1 - 0.12 11.5 0.0 9.8 5.3 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF4349 PF14257.1 CDJ62322.1 - 0.56 9.3 6.0 0.55 9.4 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) zf-MYND PF01753.13 CDJ62323.1 - 1.8e-12 46.8 12.3 3.3e-12 46.0 8.6 1.5 1 0 0 1 1 1 1 MYND finger zinc_ribbon_4 PF13717.1 CDJ62323.1 - 0.069 12.8 5.8 1.5 8.5 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CDJ62323.1 - 0.86 9.2 8.9 1.8 8.1 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF843 PF05814.6 CDJ62324.1 - 0.027 14.2 0.7 0.069 12.9 0.5 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) ETRAMP PF09716.5 CDJ62324.1 - 0.11 12.4 0.0 0.11 12.4 0.0 5.1 4 2 1 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) PWWP PF00855.12 CDJ62325.1 - 0.018 15.1 0.0 0.018 15.1 0.0 3.6 2 1 0 2 2 2 0 PWWP domain Hydrolase_3 PF08282.7 CDJ62326.1 - 4.8e-32 111.5 0.0 6.2e-24 84.9 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CDJ62326.1 - 1.6e-10 40.6 0.0 2.9e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase AIF_C PF14721.1 CDJ62327.1 - 0.015 15.5 6.1 0.016 15.4 4.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1764 PF08576.5 CDJ62327.1 - 0.2 12.4 8.6 0.23 12.2 5.9 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Lipase_GDSL_3 PF14606.1 CDJ62327.1 - 0.47 10.1 5.2 0.49 10.1 3.6 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CbiG_mid PF11761.3 CDJ62327.1 - 0.54 10.5 4.1 0.81 9.9 2.8 1.5 1 1 0 1 1 1 0 Cobalamin biosynthesis central region DUF912 PF06024.7 CDJ62327.1 - 0.59 10.2 4.9 0.83 9.7 3.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CDJ62327.1 - 0.62 9.0 18.5 0.63 9.0 12.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein Pex14_N PF04695.8 CDJ62327.1 - 0.69 9.9 18.5 0.86 9.6 12.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gti1_Pac2 PF09729.4 CDJ62327.1 - 0.72 9.6 5.7 0.77 9.6 3.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Folate_carrier PF01770.13 CDJ62327.1 - 0.74 8.2 7.2 0.8 8.1 5.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier PAT1 PF09770.4 CDJ62327.1 - 0.87 7.7 32.1 0.84 7.7 22.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peroxin-13_N PF04088.8 CDJ62327.1 - 0.89 9.4 5.7 1 9.3 4.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FixO PF02433.10 CDJ62327.1 - 0.96 8.7 7.1 1 8.6 4.9 1.0 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO SeqA PF03925.8 CDJ62327.1 - 1.3 8.6 10.9 1.4 8.6 7.6 1.1 1 0 0 1 1 1 0 SeqA protein AAA_28 PF13521.1 CDJ62327.1 - 1.3 8.9 7.9 1.5 8.7 5.4 1.1 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 CDJ62327.1 - 1.3 8.5 5.7 1.6 8.3 4.0 1.0 1 0 0 1 1 1 0 Helicase Glyco_transf_15 PF01793.11 CDJ62327.1 - 1.4 7.7 8.8 1.5 7.6 6.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DHHW PF14286.1 CDJ62327.1 - 1.5 8.0 7.0 1.5 8.0 4.8 1.0 1 0 0 1 1 1 0 DHHW protein SprA-related PF12118.3 CDJ62327.1 - 1.5 8.0 29.3 1.6 7.9 20.3 1.1 1 0 0 1 1 1 0 SprA-related family EIIBC-GUT_N PF03612.9 CDJ62327.1 - 1.5 8.3 9.0 1.7 8.2 6.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Calici_coat_C PF08435.6 CDJ62327.1 - 1.5 8.0 8.4 1.7 7.9 5.8 1.0 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal RNA_pol_Rpb1_2 PF00623.15 CDJ62327.1 - 1.6 8.6 7.3 1.8 8.5 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Serinc PF03348.10 CDJ62327.1 - 1.9 7.1 9.6 1.9 7.0 6.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.15 CDJ62327.1 - 2 6.3 9.9 2.1 6.2 6.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF775 PF05603.7 CDJ62327.1 - 2.2 7.7 13.9 2.8 7.4 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF822 PF05687.8 CDJ62327.1 - 2.9 8.2 8.4 3.3 8.0 5.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Baculo_PP31 PF05311.6 CDJ62327.1 - 3 7.0 10.3 3 7.0 7.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Band_3_cyto PF07565.8 CDJ62327.1 - 3.3 7.1 11.6 3.3 7.1 8.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TFIIA PF03153.8 CDJ62327.1 - 3.5 7.4 25.1 3.3 7.5 17.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 CDJ62327.1 - 3.8 7.1 16.2 4.8 6.8 11.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) P5-ATPase PF12409.3 CDJ62327.1 - 4 7.3 7.3 4.3 7.2 5.1 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter Peptidase_U57 PF05582.7 CDJ62327.1 - 4.5 6.1 9.7 5.1 5.9 6.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Neur_chan_memb PF02932.11 CDJ62327.1 - 4.7 7.0 5.5 4.7 7.0 3.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S15 PF02129.13 CDJ62327.1 - 4.8 6.5 9.6 5 6.4 6.7 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Endonuc_Holl PF10107.4 CDJ62327.1 - 4.9 6.8 13.4 5.5 6.6 9.3 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Gemini_AL2 PF01440.11 CDJ62327.1 - 5.1 7.1 18.6 6.7 6.8 12.9 1.3 1 0 0 1 1 1 0 Geminivirus AL2 protein ATAD4 PF15321.1 CDJ62327.1 - 5.3 8.1 10.4 7.4 7.6 7.2 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Med15 PF09606.5 CDJ62327.1 - 5.5 5.0 50.2 5.2 5.1 34.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3708 PF12501.3 CDJ62327.1 - 6.1 6.6 7.5 6.7 6.5 5.2 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF4557 PF15101.1 CDJ62327.1 - 7.9 6.2 23.3 9 6.0 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PCNA_N PF00705.13 CDJ62328.1 - 5e-44 148.8 4.9 2.2e-43 146.7 1.7 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CDJ62328.1 - 2.3e-27 95.4 0.1 9.8e-27 93.3 0.0 2.1 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CDJ62328.1 - 8.7e-08 31.5 1.1 2.7e-07 29.9 0.8 1.7 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.11 CDJ62328.1 - 0.00056 18.7 0.1 0.021 13.5 0.1 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Metallophos PF00149.23 CDJ62330.1 - 3.3e-36 124.5 0.1 5.2e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pribosyltran PF00156.22 CDJ62330.1 - 4.2e-08 32.9 0.0 4.2e-08 32.9 0.0 3.5 2 1 0 2 2 2 1 Phosphoribosyl transferase domain DUF605 PF04652.11 CDJ62330.1 - 0.00017 21.1 28.5 0.00017 21.1 19.7 5.0 2 1 2 4 4 4 1 Vta1 like SR-25 PF10500.4 CDJ62330.1 - 0.00041 19.9 13.5 0.00041 19.9 9.4 7.8 3 2 1 4 4 4 1 Nuclear RNA-splicing-associated protein SAP PF02037.22 CDJ62331.1 - 2.8e-09 36.2 0.0 5.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 SAP domain PAT1 PF09770.4 CDJ62331.1 - 0.71 8.0 49.6 0.8 7.8 34.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CSL PF05207.8 CDJ62331.1 - 0.96 9.0 4.5 1.9 8.0 3.1 1.4 1 0 0 1 1 1 0 CSL zinc finger TFIIA PF03153.8 CDJ62331.1 - 6.5 6.5 28.1 9.2 6.0 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2859 PF11072.3 CDJ62332.1 - 1.2 8.5 11.2 3.2 7.2 7.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2859) PAT1 PF09770.4 CDJ62332.1 - 2.8 6.0 29.1 3.3 5.8 20.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ62332.1 - 3 5.9 42.9 4.8 5.2 29.8 1.3 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 CDJ62332.1 - 5.5 4.5 8.4 6.4 4.3 5.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDJ62332.1 - 5.9 5.2 11.7 8.5 4.7 8.1 1.2 1 0 0 1 1 1 0 Raftlin CIAPIN1 PF05093.8 CDJ62333.1 - 6.8e-06 26.1 8.3 0.0017 18.4 5.7 2.6 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis APS_kinase PF01583.15 CDJ62334.1 - 4e-41 140.2 0.6 6.6e-21 74.6 0.0 3.3 2 1 1 3 3 3 3 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 CDJ62334.1 - 7.5e-37 126.7 0.0 1.3e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CDJ62334.1 - 2.1e-31 108.4 0.1 3.6e-30 104.4 0.0 2.2 1 1 0 1 1 1 1 PUA-like domain ACDC PF14733.1 CDJ62335.1 - 1.3e-14 54.1 0.1 3.2e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CDJ62335.1 - 2.9e-06 27.3 4.6 2.9e-06 27.3 3.2 2.7 3 0 0 3 3 3 1 AP2 domain SRP-alpha_N PF04086.8 CDJ62335.1 - 0.17 11.2 6.8 0.13 11.6 2.8 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Laminin_G_3 PF13385.1 CDJ62336.1 - 3.8e-09 36.9 0.0 6.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CDJ62336.1 - 0.0059 16.6 0.0 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain Transposase_22 PF02994.9 CDJ62339.1 - 0.081 11.4 1.6 2.2 6.6 0.2 2.2 1 1 0 2 2 2 0 L1 transposable element DnaJ PF00226.26 CDJ62340.1 - 1.7e-09 37.2 0.1 4.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain SecE PF00584.15 CDJ62340.1 - 0.018 14.6 2.5 0.033 13.7 1.7 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4366 PF14283.1 CDJ62340.1 - 0.11 11.9 0.1 0.11 11.9 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Ribosomal_60s PF00428.14 CDJ62340.1 - 1.9 8.9 12.2 6.1 7.3 3.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein PITH PF06201.8 CDJ62342.1 - 8.7e-22 77.5 0.0 1.5e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 PITH domain Med3 PF11593.3 CDJ62342.1 - 7.5 5.6 11.3 8.7 5.4 7.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LETM1 PF07766.8 CDJ62344.1 - 6.3e-64 215.5 1.9 6.3e-64 215.5 1.3 2.2 2 0 0 2 2 2 1 LETM1-like protein Surface_antigen PF11054.3 CDJ62346.1 - 4.5e-214 707.7 15.3 9.6e-109 362.6 3.6 2.0 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen OmdA PF13376.1 CDJ62346.1 - 0.017 14.7 0.1 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Transglut_C PF00927.17 CDJ62346.1 - 0.018 15.0 1.5 4.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain NUP PF06516.6 CDJ62346.1 - 0.31 9.8 4.3 3.2 6.4 0.2 2.3 2 0 0 2 2 2 0 Purine nucleoside permease (NUP) Surface_antigen PF11054.3 CDJ62347.1 - 1.1e-106 355.8 2.8 1.3e-106 355.7 2.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62348.1 - 9.5e-106 352.8 0.5 1.1e-105 352.6 0.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62349.1 - 8.7e-109 362.7 2.3 9.7e-109 362.6 1.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62350.1 - 5.5e-102 340.5 6.1 6.2e-102 340.3 4.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62351.1 - 1e-105 352.7 7.2 1.2e-105 352.5 5.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62353.1 - 6.8e-106 353.3 4.2 7.6e-106 353.1 2.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62354.1 - 5.4e-103 343.8 5.5 6.1e-103 343.6 3.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Transglut_C PF00927.17 CDJ62354.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain ABC_tran PF00005.22 CDJ62355.1 - 1.7e-32 112.5 0.0 3.2e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CDJ62355.1 - 2.2e-17 63.4 8.6 3.2e-17 62.8 5.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CDJ62355.1 - 2.6e-06 27.6 0.0 0.0061 16.5 0.0 2.2 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CDJ62355.1 - 0.00011 21.5 0.0 0.0053 16.0 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CDJ62355.1 - 0.00034 20.6 0.8 0.00086 19.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 CDJ62355.1 - 0.0033 16.3 0.0 0.0065 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 CDJ62355.1 - 0.0035 16.8 0.0 0.0093 15.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CDJ62355.1 - 0.0039 16.2 0.0 0.0078 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CDJ62355.1 - 0.0041 17.2 0.0 0.057 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CDJ62355.1 - 0.006 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CDJ62355.1 - 0.031 14.5 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CDJ62355.1 - 0.033 14.0 0.2 0.42 10.5 0.2 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 CDJ62355.1 - 0.034 13.7 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CDJ62355.1 - 0.048 14.4 0.0 0.1 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_membrane_2 PF06472.10 CDJ62355.1 - 0.06 12.4 1.8 0.11 11.6 1.3 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 DUF258 PF03193.11 CDJ62355.1 - 0.063 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CDJ62355.1 - 0.088 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CDJ62355.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein DEAD PF00270.24 CDJ62355.1 - 0.1 12.0 0.1 3 7.2 0.1 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase NB-ARC PF00931.17 CDJ62355.1 - 0.14 11.0 0.0 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 CDJ62355.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Pox_A32 PF04665.7 CDJ62355.1 - 0.22 10.7 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein TMEM52 PF14979.1 CDJ62356.1 - 0.049 13.5 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane 52 Bax1-I PF01027.15 CDJ62356.1 - 0.072 12.6 0.4 0.07 12.7 0.2 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Oxidored_q2 PF00420.19 CDJ62356.1 - 0.74 9.4 4.0 1.4 8.6 2.7 1.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L L51_S25_CI-B8 PF05047.11 CDJ62357.1 - 0.00023 20.8 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DAGAT PF03982.8 CDJ62358.1 - 1e-29 103.1 0.0 1.7e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 CDJ62358.1 - 0.0027 17.1 0.0 0.0087 15.4 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase Pkinase PF00069.20 CDJ62359.1 - 6.7e-70 235.2 0.0 1e-69 234.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62359.1 - 2.1e-32 112.2 0.0 3.4e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ62359.1 - 1.3e-05 24.2 1.6 2e-05 23.7 0.0 2.0 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 CDJ62359.1 - 0.009 15.0 0.5 0.024 13.6 0.3 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAT1 PF09770.4 CDJ62359.1 - 2 6.5 27.0 2.8 6.0 18.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 APH PF01636.18 CDJ62359.1 - 2.1 7.9 0.0 2.1 7.9 0.0 3.1 2 2 1 3 3 3 0 Phosphotransferase enzyme family Spt20 PF12090.3 CDJ62360.1 - 0.13 11.6 6.3 0.27 10.5 4.4 1.5 1 0 0 1 1 1 0 Spt20 family OATP PF03137.15 CDJ62360.1 - 1.4 6.8 3.9 2.3 6.1 2.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Phosducin PF02114.11 CDJ62362.1 - 0.12 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Phosducin Nif11 PF07862.6 CDJ62362.1 - 4.6 7.2 6.5 12 5.9 0.2 3.6 4 0 0 4 4 4 0 Nitrogen fixation protein of unknown function Myb_DNA-bind_6 PF13921.1 CDJ62363.1 - 2e-06 27.8 0.7 3e-06 27.2 0.5 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDJ62363.1 - 0.0037 17.2 0.2 0.006 16.6 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2453 PF10507.4 CDJ62364.1 - 3.9e-25 87.7 12.3 1.9e-23 82.3 1.6 4.4 5 1 0 5 5 5 2 Protein of unknown function (DUF2453) GAF_3 PF13492.1 CDJ62364.1 - 0.0002 21.4 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain Fra10Ac1 PF09725.4 CDJ62365.1 - 1.4e-21 76.7 0.0 9.6e-21 74.0 0.0 2.1 1 1 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 PLRV_ORF5 PF01690.12 CDJ62367.1 - 1.2 8.2 13.4 1.4 7.9 9.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Macoilin PF09726.4 CDJ62367.1 - 1.7 6.8 25.6 2 6.5 17.8 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CDJ62367.1 - 4.3 7.1 27.0 5.3 6.8 18.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.4 CDJ62367.1 - 7.2 5.1 17.3 9 4.8 12.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tmemb_cc2 PF10267.4 CDJ62367.1 - 9 4.7 17.5 12 4.3 12.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2807 PF10988.3 CDJ62368.1 - 0.054 13.0 6.5 0.063 12.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2807) Med15 PF09606.5 CDJ62368.1 - 0.67 8.0 29.0 0.72 7.9 20.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Helicase_C PF00271.26 CDJ62369.1 - 1e-20 73.3 0.1 1.4e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VAD1-2 PF15310.1 CDJ62369.1 - 0.073 12.7 0.0 11 5.5 0.0 2.0 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling PAT1 PF09770.4 CDJ62370.1 - 0.0033 15.7 33.9 0.0044 15.3 23.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDJ62370.1 - 0.1 12.6 21.5 0.27 11.2 14.9 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK5_activator PF03261.10 CDJ62370.1 - 0.39 10.0 18.5 0.5 9.6 12.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein FNIP_N PF14636.1 CDJ62370.1 - 0.62 10.5 15.6 1.2 9.5 10.8 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus BORG_CEP PF14957.1 CDJ62370.1 - 1.6 9.6 15.9 3 8.7 11.0 1.4 1 0 0 1 1 1 0 Cdc42 effector DUF4220 PF13968.1 CDJ62370.1 - 1.7 7.6 6.9 2.3 7.2 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SAGA-Tad1 PF12767.2 CDJ62370.1 - 2.3 7.8 23.6 3.4 7.2 16.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DDHD PF02862.12 CDJ62370.1 - 2.5 7.8 16.6 3.6 7.3 11.5 1.2 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 CDJ62370.1 - 3 7.3 19.3 4.8 6.6 13.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF-3_zeta PF05091.7 CDJ62370.1 - 3.1 6.2 20.8 4.1 5.8 14.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S15 PF02129.13 CDJ62370.1 - 4.3 6.6 15.0 7 5.9 10.4 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ycf1 PF05758.7 CDJ62370.1 - 4.6 4.8 18.6 6 4.4 12.9 1.0 1 0 0 1 1 1 0 Ycf1 DUF4175 PF13779.1 CDJ62370.1 - 4.7 4.7 49.5 6.8 4.2 34.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 CDJ62370.1 - 4.8 6.8 25.6 6.9 6.3 17.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.17 CDJ62370.1 - 5.6 5.8 6.4 8.6 5.2 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2215 PF10225.4 CDJ62370.1 - 7.8 5.8 7.4 12 5.2 5.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Atg8 PF02991.11 CDJ62372.1 - 6.8e-33 112.7 0.1 1.2e-32 111.9 0.1 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CDJ62372.1 - 2.1e-05 24.5 0.1 6.2e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 RskA PF10099.4 CDJ62375.1 - 0.0042 16.8 9.9 0.0042 16.8 6.9 2.1 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Senescence_reg PF04520.8 CDJ62376.1 - 0.059 13.8 0.9 0.086 13.3 0.6 1.3 1 0 0 1 1 1 0 Senescence regulator Med15 PF09606.5 CDJ62376.1 - 0.12 10.5 16.0 0.16 10.1 11.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDJ62376.1 - 0.14 10.9 13.0 0.17 10.5 9.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.8 CDJ62376.1 - 0.28 11.0 7.7 0.37 10.6 5.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ62376.1 - 0.3 9.2 10.3 0.35 9.0 7.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FoP_duplication PF13865.1 CDJ62377.1 - 0.01 16.2 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_60s PF00428.14 CDJ62377.1 - 0.054 13.9 6.3 0.055 13.8 4.4 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ala_racemase_N PF01168.15 CDJ62378.1 - 2.2e-36 125.4 3.3 2.2e-36 125.4 2.3 2.0 1 1 1 2 2 2 1 Alanine racemase, N-terminal domain DUF1048 PF06304.6 CDJ62378.1 - 0.13 12.5 0.4 25 5.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1048) DUF2029 PF09594.5 CDJ62379.1 - 2.7e-05 23.7 6.7 5.5e-05 22.7 4.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) DNA_primase_S PF01896.14 CDJ62379.1 - 0.00088 19.0 0.0 0.68 9.7 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic and archaeal DNA primase small subunit PAT1 PF09770.4 CDJ62379.1 - 0.14 10.3 33.1 0.19 9.9 22.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rifin_STEVOR PF02009.11 CDJ62379.1 - 7.1 6.1 12.9 0.14 11.7 0.7 2.2 2 0 0 2 2 2 0 Rifin/stevor family DUF4614 PF15391.1 CDJ62380.1 - 0.35 10.6 9.1 0.39 10.4 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CAF-1_p150 PF11600.3 CDJ62380.1 - 0.72 9.1 7.0 0.82 9.0 4.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4603 PF15376.1 CDJ62380.1 - 1.6 5.8 11.3 1.6 5.7 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) AF-4 PF05110.8 CDJ62380.1 - 2.7 5.7 17.8 2.5 5.8 12.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3486 PF11985.3 CDJ62380.1 - 3.1 7.8 15.4 3.5 7.6 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Macoilin PF09726.4 CDJ62380.1 - 4 5.6 14.1 4.3 5.4 9.8 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CDJ62380.1 - 4.2 7.1 9.1 4.8 6.9 6.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Corona_nucleoca PF00937.13 CDJ62380.1 - 6.9 5.5 10.3 7.9 5.3 7.1 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF737 PF05300.6 CDJ62380.1 - 7.2 6.5 9.0 8.7 6.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) RAP1 PF07218.6 CDJ62380.1 - 9.5 4.1 19.6 9.5 4.1 13.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.11 CDJ62381.1 - 0.0016 17.2 4.0 0.0016 17.2 2.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Radial_spoke PF04712.7 CDJ62381.1 - 0.082 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DDHD PF02862.12 CDJ62381.1 - 1.5 8.5 7.7 27 4.4 3.8 2.2 2 0 0 2 2 2 0 DDHD domain HTH_42 PF06224.7 CDJ62383.1 - 0.064 12.5 5.0 0.067 12.5 3.4 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain RskA PF10099.4 CDJ62383.1 - 0.25 11.0 11.4 0.36 10.5 7.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FGE-sulfatase PF03781.11 CDJ62383.1 - 0.27 10.5 3.6 0.34 10.2 2.5 1.2 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 Adeno_hexon PF01065.14 CDJ62383.1 - 0.27 10.0 1.9 0.31 9.8 1.3 1.0 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain SR-25 PF10500.4 CDJ62383.1 - 0.32 10.4 17.4 0.38 10.1 12.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.12 CDJ62383.1 - 0.39 9.4 5.5 0.43 9.3 3.8 1.0 1 0 0 1 1 1 0 Presenilin DDHD PF02862.12 CDJ62383.1 - 0.43 10.3 7.9 0.52 10.0 5.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF2894 PF11445.3 CDJ62383.1 - 0.73 10.0 12.4 0.92 9.7 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) TFIIA PF03153.8 CDJ62383.1 - 1.2 8.9 9.5 1.4 8.7 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpc4 PF05132.9 CDJ62383.1 - 1.5 8.8 4.3 2.3 8.2 3.0 1.5 1 1 0 1 1 1 0 RNA polymerase III RPC4 Ctr PF04145.10 CDJ62383.1 - 7.6 6.5 6.2 8.2 6.4 4.0 1.3 1 1 0 1 1 1 0 Ctr copper transporter family 4HBT PF03061.17 CDJ62385.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Pkinase PF00069.20 CDJ62387.1 - 4.2e-36 124.4 0.0 6.8e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62387.1 - 4.9e-20 71.6 0.0 9.1e-20 70.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ62387.1 - 0.0004 19.4 0.0 0.012 14.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDJ62387.1 - 0.0016 18.2 1.2 0.0046 16.7 0.8 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDJ62387.1 - 0.042 12.9 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CDJ62387.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DLH PF01738.13 CDJ62388.1 - 0.38 9.9 7.3 0.021 14.1 1.2 1.6 1 1 1 2 2 2 0 Dienelactone hydrolase family DUF2029 PF09594.5 CDJ62388.1 - 1.8 7.9 10.8 0.09 12.2 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) DUF3157 PF11355.3 CDJ62390.1 - 0.24 10.6 6.0 0.3 10.3 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) DUF3043 PF11241.3 CDJ62390.1 - 0.24 10.9 1.3 0.29 10.7 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) MASE1 PF05231.9 CDJ62390.1 - 1.8 7.4 8.3 1.2 8.0 1.4 2.0 2 0 0 2 2 2 0 MASE1 Collagen PF01391.13 CDJ62391.1 - 8.9e-09 34.7 31.5 8.9e-09 34.7 21.8 6.5 6 0 0 6 6 6 1 Collagen triple helix repeat (20 copies) DnaJ PF00226.26 CDJ62392.1 - 5.9e-16 57.9 0.1 1.9e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 DnaJ domain Daxx PF03344.10 CDJ62392.1 - 0.15 10.5 6.4 0.19 10.1 4.4 1.0 1 0 0 1 1 1 0 Daxx Family Snf7 PF03357.16 CDJ62393.1 - 0.00018 20.9 2.0 0.00034 20.0 1.4 1.4 1 1 0 1 1 1 1 Snf7 ApoL PF05461.6 CDJ62393.1 - 0.0007 18.9 0.5 0.0013 18.1 0.3 1.3 1 0 0 1 1 1 1 Apolipoprotein L DUF4341 PF14241.1 CDJ62394.1 - 0.1 12.2 0.7 0.41 10.3 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4341) zf-CCHC PF00098.18 CDJ62396.1 - 9.4e-07 28.4 4.6 0.0094 15.8 0.4 2.6 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ62396.1 - 0.11 12.5 4.2 0.28 11.2 2.9 1.7 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.1 CDJ62396.1 - 0.28 10.6 0.1 0.28 10.6 0.1 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ62396.1 - 0.39 10.4 4.2 1.6 8.5 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle SUI1 PF01253.17 CDJ62399.1 - 5.2e-27 93.4 0.4 8.4e-27 92.8 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 HA2 PF04408.18 CDJ62400.1 - 1.9e-29 101.6 0.0 4.5e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CDJ62400.1 - 1.4e-28 99.0 0.0 5.6e-28 97.0 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CDJ62400.1 - 1.2e-09 37.8 0.0 3.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CDJ62400.1 - 2.8e-07 30.4 0.0 6.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CDJ62400.1 - 4.8e-06 26.1 0.4 1.8e-05 24.3 0.1 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDJ62400.1 - 1.3e-05 25.3 0.0 4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CDJ62400.1 - 0.0016 17.4 0.2 0.0063 15.4 0.1 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 CDJ62400.1 - 0.002 17.8 0.1 0.0078 15.9 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 CDJ62400.1 - 0.04 13.3 0.0 3.2 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 CDJ62400.1 - 0.046 12.9 0.4 0.21 10.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein DAP3 PF10236.4 CDJ62400.1 - 0.15 10.9 0.1 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Pkinase PF00069.20 CDJ62401.1 - 9.7e-56 188.7 0.3 5.8e-54 182.9 0.0 3.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62401.1 - 2.2e-35 122.0 0.1 8.1e-33 113.5 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase DUF4203 PF13886.1 CDJ62401.1 - 0.9 8.9 0.0 1.6 8.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) EF-hand_1 PF00036.27 CDJ62401.1 - 1.2 8.6 0.0 2.2 7.8 0.0 1.5 1 0 0 1 1 1 0 EF hand DUF2617 PF10936.3 CDJ62403.1 - 0.025 14.1 0.6 0.06 12.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2617 Myb_DNA-binding PF00249.26 CDJ62404.1 - 7.5e-21 73.9 0.0 9.1e-08 32.0 0.0 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDJ62404.1 - 2.2e-16 59.6 0.0 2.5e-06 27.4 0.0 4.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain RRM_3 PF08777.6 CDJ62404.1 - 0.07 12.9 1.5 0.42 10.4 1.0 2.4 1 0 0 1 1 1 0 RNA binding motif ISG65-75 PF11727.3 CDJ62405.1 - 0.0063 15.6 4.5 0.0075 15.3 3.1 1.0 1 0 0 1 1 1 1 Invariant surface glycoprotein Syntaxin PF00804.20 CDJ62405.1 - 0.016 15.3 7.4 0.021 14.9 5.1 1.2 1 0 0 1 1 1 0 Syntaxin Sec20 PF03908.8 CDJ62405.1 - 0.026 14.2 3.5 0.029 14.0 2.4 1.1 1 0 0 1 1 1 0 Sec20 AICARFT_IMPCHas PF01808.13 CDJ62405.1 - 0.026 13.6 0.4 0.03 13.4 0.2 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Vps51 PF08700.6 CDJ62405.1 - 0.031 14.1 6.7 8.2 6.3 4.6 2.2 1 1 0 1 1 1 0 Vps51/Vps67 DUF1759 PF03564.10 CDJ62405.1 - 0.033 14.0 1.1 0.035 13.9 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF2115 PF09888.4 CDJ62405.1 - 0.046 13.8 1.9 0.051 13.6 1.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Mitovir_RNA_pol PF05919.6 CDJ62405.1 - 0.065 12.1 1.1 0.068 12.1 0.7 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Fmp27_WPPW PF10359.4 CDJ62405.1 - 0.075 11.4 5.7 0.072 11.5 4.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.8 CDJ62405.1 - 0.086 11.9 2.9 0.089 11.8 2.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein L-fibroin PF05849.6 CDJ62405.1 - 0.087 12.1 0.0 0.093 12.0 0.0 1.1 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) DUF4407 PF14362.1 CDJ62405.1 - 0.091 11.6 6.8 0.098 11.5 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 CDJ62405.1 - 0.094 11.6 6.3 0.098 11.5 4.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FAD-SLDH PF12318.3 CDJ62405.1 - 0.1 12.3 1.6 0.12 12.0 1.1 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase GCIP PF13324.1 CDJ62405.1 - 0.12 11.6 2.9 0.13 11.4 2.0 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4248 PF14053.1 CDJ62405.1 - 0.13 11.8 0.6 0.22 11.1 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4248) EMP24_GP25L PF01105.19 CDJ62405.1 - 0.2 11.3 1.8 0.23 11.1 1.2 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Prp18 PF02840.10 CDJ62405.1 - 0.24 11.1 2.9 0.27 11.0 2.0 1.1 1 0 0 1 1 1 0 Prp18 domain DUF3573 PF12097.3 CDJ62405.1 - 0.27 9.8 1.8 0.26 9.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Fzo_mitofusin PF04799.8 CDJ62405.1 - 0.28 10.5 4.9 0.33 10.3 3.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region LOH1CR12 PF10158.4 CDJ62405.1 - 0.31 10.8 6.1 0.39 10.5 4.2 1.1 1 0 0 1 1 1 0 Tumour suppressor protein His_Phos_2 PF00328.17 CDJ62405.1 - 0.31 10.3 4.3 0.35 10.1 3.0 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF2937 PF11157.3 CDJ62405.1 - 0.36 10.1 6.0 0.47 9.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) GNT-I PF03071.10 CDJ62405.1 - 0.4 9.1 3.5 0.44 9.0 2.4 1.0 1 0 0 1 1 1 0 GNT-I family DUF342 PF03961.8 CDJ62405.1 - 0.52 8.6 4.2 0.55 8.5 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4446 PF14584.1 CDJ62405.1 - 0.54 10.0 3.2 0.68 9.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) H-kinase_dim PF02895.9 CDJ62405.1 - 0.6 10.4 5.5 1 9.7 3.8 1.5 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain HAUS6_N PF14661.1 CDJ62405.1 - 0.62 9.3 7.8 0.6 9.4 5.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 CDJ62405.1 - 0.67 7.7 5.9 0.65 7.7 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 CDJ62405.1 - 0.69 10.2 6.7 0.75 10.0 4.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3782 PF12644.2 CDJ62405.1 - 0.84 9.4 3.4 1.3 8.8 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Spectrin PF00435.16 CDJ62405.1 - 0.93 9.8 12.6 1.6 9.0 8.7 1.4 1 1 0 1 1 1 0 Spectrin repeat LMBR1 PF04791.11 CDJ62405.1 - 0.93 7.9 2.5 0.97 7.9 1.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Herpes_UL25 PF01499.11 CDJ62405.1 - 1.3 7.2 6.4 1.2 7.3 4.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF2076 PF09849.4 CDJ62405.1 - 1.6 8.7 8.6 3.4 7.6 6.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) OmpH PF03938.9 CDJ62405.1 - 1.7 8.5 13.7 2 8.3 9.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3571 PF12095.3 CDJ62405.1 - 1.9 8.7 6.2 2.4 8.4 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3571) DUF972 PF06156.8 CDJ62405.1 - 2.5 8.4 7.6 3.3 8.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) YkuI_C PF10388.4 CDJ62405.1 - 2.8 7.6 6.8 2.9 7.5 4.4 1.3 1 1 0 1 1 1 0 EAL-domain associated signalling protein domain IncA PF04156.9 CDJ62405.1 - 4.6 6.7 14.7 5.6 6.5 10.2 1.3 1 1 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 CDJ62405.1 - 9.8 4.3 10.9 9.5 4.3 7.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF_4EBP PF05456.6 CDJ62406.1 - 2.2 8.0 8.3 4.2 7.0 5.7 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FimP PF09766.4 CDJ62406.1 - 6.1 5.7 20.9 7.8 5.4 14.5 1.2 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 CDJ62406.1 - 9 4.3 43.3 14 3.7 30.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Yip1 PF04893.12 CDJ62407.1 - 0.019 14.4 0.1 0.036 13.5 0.1 1.5 1 0 0 1 1 1 0 Yip1 domain Ribosomal_60s PF00428.14 CDJ62407.1 - 0.078 13.3 2.0 0.21 11.9 1.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein WD40 PF00400.27 CDJ62408.1 - 1.8e-25 87.8 6.6 1.1e-08 34.6 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CDJ62408.1 - 0.00067 19.1 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain BBS2_Mid PF14783.1 CDJ62408.1 - 0.032 14.0 0.0 0.42 10.3 0.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Dehydrin PF00257.14 CDJ62409.1 - 0.016 15.5 1.8 0.019 15.2 1.2 1.2 1 0 0 1 1 1 0 Dehydrin DUF3108 PF11306.3 CDJ62409.1 - 8.9 5.8 9.8 22 4.5 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3108) RtcB PF01139.12 CDJ62411.1 - 1.7e-37 129.4 0.1 9e-33 113.8 0.0 2.1 1 1 1 2 2 2 2 tRNA-splicing ligase RtcB DUF58 PF01882.13 CDJ62412.1 - 0.012 15.7 2.6 0.028 14.5 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF58 CAF-1_p150 PF11600.3 CDJ62412.1 - 0.16 11.3 16.0 0.26 10.6 11.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4241 PF14025.1 CDJ62412.1 - 0.42 10.3 2.4 0.49 10.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) SR-25 PF10500.4 CDJ62412.1 - 3.1 7.2 26.2 3.8 6.9 6.2 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.12 CDJ62412.1 - 3.4 6.3 14.5 3.9 6.1 10.1 1.0 1 0 0 1 1 1 0 Presenilin Herpes_UL87 PF03043.9 CDJ62412.1 - 8.5 4.6 9.4 9.1 4.5 6.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family FLO_LFY PF01698.11 CDJ62412.1 - 9.2 4.9 14.0 12 4.6 9.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Rtf2 PF04641.7 CDJ62412.1 - 9.5 5.3 14.9 13 4.9 10.3 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DJ-1_PfpI PF01965.19 CDJ62415.1 - 2.2e-07 30.4 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Thioredoxin_3 PF13192.1 CDJ62415.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Nol1_Nop2_Fmu PF01189.12 CDJ62416.1 - 6.9e-10 38.7 1.0 8e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CDJ62416.1 - 0.11 12.5 1.2 3.9 7.5 0.1 3.2 2 1 0 2 2 2 0 Methyltransferase domain GTP_EFTU PF00009.22 CDJ62417.1 - 1.8e-39 135.0 0.0 5.6e-39 133.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CDJ62417.1 - 2.2e-29 101.0 0.0 4.3e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CDJ62417.1 - 5e-29 100.2 0.0 1.5e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CDJ62417.1 - 3e-22 78.3 0.1 7.7e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CDJ62417.1 - 9.8e-13 48.0 0.0 2.5e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDJ62418.1 - 3.8e-11 42.9 0.0 8.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDJ62418.1 - 2.2e-09 37.0 0.0 1.4e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CDJ62418.1 - 0.0011 18.9 6.9 0.0026 17.7 4.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CDJ62418.1 - 0.015 14.4 0.3 0.07 12.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 CDJ62418.1 - 0.016 15.6 0.0 0.045 14.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 CDJ62418.1 - 0.025 13.8 0.1 0.53 9.5 0.0 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B Septin PF00735.13 CDJ62418.1 - 0.056 12.4 0.6 0.24 10.3 0.4 1.9 1 1 0 1 1 1 0 Septin ECH_C PF13766.1 CDJ62419.1 - 5.9e-22 78.0 9.0 2.7e-15 56.5 0.1 3.1 3 0 0 3 3 3 2 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CDJ62419.1 - 7.5e-22 77.6 0.0 7.5e-22 77.6 0.0 2.2 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase family Pex14_N PF04695.8 CDJ62419.1 - 1 9.4 7.2 0.68 9.9 0.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 PF10152.4 CDJ62419.1 - 1.3 9.2 7.1 0.39 10.9 1.6 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pro_isomerase PF00160.16 CDJ62420.1 - 1.9e-47 161.3 0.1 1.9e-47 161.3 0.0 2.2 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CDJ62420.1 - 5.1e-11 42.0 2.7 0.0054 16.5 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat zf-C3HC4_3 PF13920.1 CDJ62421.1 - 9.2e-09 34.8 14.5 1.4e-08 34.2 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ62421.1 - 2e-05 24.4 15.4 3.7e-05 23.6 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDJ62421.1 - 0.0032 17.1 14.1 0.0053 16.3 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ62421.1 - 0.0064 16.2 14.6 0.011 15.5 10.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-P11 PF03854.9 CDJ62421.1 - 0.074 12.5 13.5 0.18 11.2 4.9 2.3 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_5 PF14634.1 CDJ62421.1 - 8.4 6.2 18.5 14 5.5 12.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain EMP24_GP25L PF01105.19 CDJ62422.1 - 2.6e-35 121.7 0.0 3.3e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1759 PF03564.10 CDJ62422.1 - 0.033 13.9 0.1 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Tna_leader PF08053.6 CDJ62422.1 - 3.8 6.9 6.1 2 7.8 1.0 2.6 2 0 0 2 2 2 0 Tryptophanese operon leader peptide HEAT_2 PF13646.1 CDJ62423.1 - 3.5e-06 27.1 30.2 0.035 14.3 0.7 7.2 5 3 2 7 7 7 4 HEAT repeats HEAT PF02985.17 CDJ62423.1 - 0.34 11.0 20.8 2.8 8.2 0.0 8.2 9 0 0 9 9 9 0 HEAT repeat HEAT_EZ PF13513.1 CDJ62423.1 - 5.4 7.6 44.4 8.1 7.0 0.1 11.4 10 3 1 11 11 11 0 HEAT-like repeat PfkB PF00294.19 CDJ62424.1 - 1.9e-43 148.7 0.4 1.4e-38 132.7 0.0 2.2 1 1 0 2 2 2 2 pfkB family carbohydrate kinase NAD_Gly3P_dh_N PF01210.18 CDJ62426.1 - 2.7e-41 140.9 0.0 4.4e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CDJ62426.1 - 2.2e-38 131.3 0.0 3.7e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CDJ62426.1 - 0.05 14.0 0.0 0.28 11.6 0.0 2.2 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-CCHC PF00098.18 CDJ62427.1 - 9.9e-08 31.5 11.0 5.1e-06 26.1 1.5 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ62427.1 - 0.003 17.1 7.7 0.0045 16.6 0.5 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ62427.1 - 0.0038 16.9 4.8 0.005 16.5 0.2 2.6 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ62427.1 - 0.0041 16.7 0.6 0.0041 16.7 0.4 2.5 2 0 0 2 2 2 1 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ62427.1 - 0.024 14.6 6.7 0.046 13.7 4.7 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.1 CDJ62427.1 - 0.3 10.6 4.5 0.24 10.9 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle DEAD PF00270.24 CDJ62428.1 - 4.3e-10 39.3 0.5 6.7e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Suf PF05843.9 CDJ62428.1 - 0.011 15.5 3.3 0.011 15.5 2.3 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ62428.1 - 0.011 15.0 1.3 0.011 15.0 0.9 1.6 2 0 0 2 2 2 0 Spt20 family ResIII PF04851.10 CDJ62428.1 - 0.065 13.0 1.8 0.18 11.6 1.3 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FimP PF09766.4 CDJ62428.1 - 0.12 11.4 8.1 0.23 10.5 5.6 1.4 1 0 0 1 1 1 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDJ62428.1 - 0.35 9.8 4.9 0.58 9.1 3.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DSPc PF00782.15 CDJ62429.1 - 1e-12 47.7 0.0 1.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CBM_20 PF00686.14 CDJ62429.1 - 0.0024 17.4 0.0 0.036 13.6 0.0 2.4 2 0 0 2 2 2 1 Starch binding domain Y_phosphatase PF00102.22 CDJ62429.1 - 0.018 14.3 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF442 PF04273.8 CDJ62429.1 - 0.069 13.0 0.1 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.1 CDJ62429.1 - 0.18 12.0 0.2 0.61 10.3 0.1 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family DivIVA PF05103.8 CDJ62429.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.5 2 0 0 2 2 2 0 DivIVA protein Myotub-related PF06602.9 CDJ62429.1 - 0.21 10.3 0.4 0.49 9.1 0.1 1.6 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain DUF3605 PF12239.3 CDJ62430.1 - 0.057 13.2 0.0 0.24 11.2 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3605) Ribosomal_L22e PF01776.12 CDJ62431.1 - 1.7e-44 150.4 2.3 2.1e-44 150.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF288 PF03385.12 CDJ62431.1 - 0.01 14.2 0.1 0.012 14.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF288 DUF3228 PF11539.3 CDJ62432.1 - 4.5e-79 264.1 0.0 5.3e-79 263.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) eIF3_p135 PF12807.2 CDJ62433.1 - 2.9e-11 43.6 0.1 9.6e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 CDJ62433.1 - 0.0057 16.5 4.2 0.076 12.9 0.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat PWI PF01480.12 CDJ62434.1 - 7.2e-28 96.5 0.0 1.1e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.13 CDJ62434.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain DIRP PF06584.8 CDJ62434.1 - 0.09 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 DIRP COX4 PF02936.9 CDJ62436.1 - 0.0035 17.0 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV PhoD PF09423.5 CDJ62438.1 - 6.9e-18 64.4 0.3 1.4e-17 63.4 0.2 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase TerD PF02342.13 CDJ62439.1 - 5.2e-12 45.4 0.0 2.8e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 TerD domain DUF948 PF06103.6 CDJ62439.1 - 0.0083 15.9 0.2 0.023 14.5 0.2 1.8 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) ACCA PF03255.9 CDJ62439.1 - 0.02 14.4 0.2 0.046 13.2 0.2 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Reo_sigmaC PF04582.7 CDJ62439.1 - 0.033 13.3 3.1 0.079 12.1 1.8 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMP_2 PF06791.8 CDJ62439.1 - 0.04 13.5 0.5 0.095 12.3 0.3 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein Baculo_PEP_C PF04513.7 CDJ62439.1 - 0.11 12.3 0.3 0.25 11.1 0.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CDJ62439.1 - 0.91 9.0 4.3 0.76 9.3 1.2 2.1 2 0 0 2 2 2 0 IncA protein DSS1_SEM1 PF05160.8 CDJ62440.1 - 0.00019 21.1 21.6 0.0079 15.9 15.0 2.2 1 1 0 1 1 1 1 DSS1/SEM1 family DEAD PF00270.24 CDJ62441.1 - 7.2e-37 126.4 0.0 1.6e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ62441.1 - 1.2e-18 66.7 0.0 2.9e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDJ62441.1 - 0.15 11.8 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Rhomboid PF01694.17 CDJ62443.1 - 4.9e-18 65.5 3.6 4.9e-18 65.5 2.5 2.1 3 0 0 3 3 3 1 Rhomboid family DUF1751 PF08551.5 CDJ62443.1 - 0.031 14.5 0.3 0.065 13.5 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) YbjQ_1 PF01906.12 CDJ62444.1 - 8.4e-19 67.9 0.5 1.3e-18 67.3 0.4 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding Tad PF13400.1 CDJ62444.1 - 1 9.4 6.8 2.7 8.1 4.7 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Pkinase PF00069.20 CDJ62445.1 - 1.7e-41 142.0 0.0 6.7e-40 136.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62445.1 - 1.4e-22 80.0 0.0 2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ62445.1 - 5.1e-09 35.5 0.0 7.6e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDJ62445.1 - 3.7e-05 23.5 0.8 7.5e-05 22.5 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Radical_SAM PF04055.16 CDJ62448.1 - 3.8e-17 62.9 0.0 9.2e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 CDJ62448.1 - 4e-15 55.4 0.3 4e-15 55.4 0.2 2.5 2 1 0 2 2 2 1 Uncharacterized protein family UPF0004 Phg_2220_C PF09524.5 CDJ62448.1 - 0.03 14.3 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) Rabaptin PF03528.10 CDJ62448.1 - 0.11 12.4 2.0 0.26 11.1 1.4 1.6 1 0 0 1 1 1 0 Rabaptin Pex14_N PF04695.8 CDJ62448.1 - 0.9 9.5 5.5 1.3 9.0 0.2 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATG_C PF09333.6 CDJ62449.1 - 0.0073 16.4 0.0 0.025 14.7 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain SSP160 PF06933.6 CDJ62450.1 - 2.4 6.0 5.2 3.4 5.5 3.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AAA_2 PF07724.9 CDJ62452.1 - 7.2e-52 175.7 0.0 1.3e-47 161.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CDJ62452.1 - 3.1e-26 92.1 0.0 2.6e-14 53.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CDJ62452.1 - 3.4e-24 84.5 1.9 3.4e-24 84.5 1.3 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 CDJ62452.1 - 5e-22 77.5 2.7 1.1e-12 47.6 0.0 3.0 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 CDJ62452.1 - 1.2e-19 70.3 0.0 7.7e-14 51.6 0.0 3.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDJ62452.1 - 3.2e-12 46.8 12.9 1.6e-05 24.9 0.0 5.9 3 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 CDJ62452.1 - 8.5e-10 38.8 0.9 0.001 19.2 0.0 4.7 3 2 1 4 4 4 2 AAA domain AAA_14 PF13173.1 CDJ62452.1 - 6.6e-08 32.5 0.0 0.0022 17.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CDJ62452.1 - 8.4e-08 31.8 0.0 1.4e-05 24.6 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 CDJ62452.1 - 2.3e-07 31.1 0.4 0.0037 17.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CDJ62452.1 - 4.7e-07 29.3 0.0 0.095 12.1 0.0 3.7 3 0 0 3 3 3 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 CDJ62452.1 - 2.6e-06 27.2 2.2 0.056 13.1 0.1 4.4 3 2 0 4 4 3 1 Archaeal ATPase AAA_17 PF13207.1 CDJ62452.1 - 8.8e-06 26.5 6.7 0.0012 19.6 0.1 4.3 2 2 0 2 2 2 1 AAA domain NACHT PF05729.7 CDJ62452.1 - 0.00018 21.1 0.0 0.16 11.6 0.0 3.1 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 CDJ62452.1 - 0.00029 20.5 0.4 0.21 11.3 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_33 PF13671.1 CDJ62452.1 - 0.00031 20.6 1.3 0.38 10.6 0.0 4.4 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 CDJ62452.1 - 0.00043 20.4 0.0 0.35 11.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 CDJ62452.1 - 0.00073 19.5 0.9 1.6 8.6 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CDJ62452.1 - 0.0011 18.3 0.1 1.4 8.2 0.0 3.6 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CDJ62452.1 - 0.0029 16.7 0.1 8.3 5.5 0.0 3.4 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 CDJ62452.1 - 0.003 17.2 0.6 7.4 6.2 0.0 3.9 4 0 0 4 4 4 0 NTPase AAA_24 PF13479.1 CDJ62452.1 - 0.0039 16.8 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CDJ62452.1 - 0.0049 16.0 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 CDJ62452.1 - 0.0063 16.1 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CDJ62452.1 - 0.014 15.0 0.0 7.6 6.1 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CDJ62452.1 - 0.014 15.6 0.0 0.65 10.2 0.0 2.8 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 CDJ62452.1 - 0.014 15.0 0.0 0.56 9.9 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF603 PF04645.7 CDJ62452.1 - 0.018 14.9 1.7 0.048 13.6 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF603 ATP_bind_1 PF03029.12 CDJ62452.1 - 0.024 14.1 0.1 0.56 9.7 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CDJ62452.1 - 0.029 14.3 0.0 11 6.0 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CDJ62452.1 - 0.035 13.5 4.0 2.1 7.7 0.0 3.9 3 1 1 4 4 4 0 AAA-like domain AAA_29 PF13555.1 CDJ62452.1 - 0.043 13.3 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DNA_pol3_delta2 PF13177.1 CDJ62452.1 - 0.046 13.3 0.0 0.46 10.1 0.0 2.5 2 1 0 2 2 2 0 DNA polymerase III, delta subunit ResIII PF04851.10 CDJ62452.1 - 0.055 13.3 0.0 3 7.6 0.0 3.2 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 CDJ62452.1 - 0.071 12.5 0.1 8.4 5.7 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Miro PF08477.8 CDJ62452.1 - 0.071 13.6 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 CDJ62452.1 - 7.2 6.8 13.4 11 6.2 0.0 3.7 2 2 0 2 2 1 0 AAA domain Lactamase_B_2 PF12706.2 CDJ62454.1 - 1e-10 41.5 0.0 8.7e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDJ62454.1 - 7e-08 32.3 0.0 2.6e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PAT1 PF09770.4 CDJ62455.1 - 0.16 10.1 10.8 0.18 10.0 7.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ62456.1 - 0.0054 15.0 30.6 0.0076 14.5 21.2 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ62456.1 - 0.2 9.8 28.7 0.23 9.6 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPR1 PF15356.1 CDJ62456.1 - 0.42 10.9 7.2 0.094 13.0 2.5 1.8 2 1 0 2 2 2 0 Psoriasis susceptibility locus 2 DUF4613 PF15390.1 CDJ62456.1 - 2.8 6.0 7.6 3.3 5.7 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CDK2AP PF09806.4 CDJ62456.1 - 3 8.0 32.5 1.9 8.6 10.8 2.1 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein Scs3p PF10261.4 CDJ62456.1 - 4.4 6.2 5.3 3.7 6.5 0.1 2.0 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM RR_TM4-6 PF06459.7 CDJ62456.1 - 7 6.4 10.3 9.6 6.0 7.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 CDJ62457.1 - 4.5e-06 26.3 0.1 0.0007 19.3 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat SF-assemblin PF06705.6 CDJ62460.1 - 0.0047 16.1 5.0 0.0062 15.7 3.3 1.4 1 1 0 1 1 1 1 SF-assemblin/beta giardin DUF4432 PF14486.1 CDJ62460.1 - 0.046 12.2 0.2 0.07 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) K-box PF01486.12 CDJ62460.1 - 0.32 10.8 11.2 0.24 11.1 6.1 2.1 2 1 0 2 2 2 0 K-box region HEAT_EZ PF13513.1 CDJ62460.1 - 2 9.0 7.1 9.4 6.8 1.3 2.6 2 1 1 3 3 3 0 HEAT-like repeat ACCA PF03255.9 CDJ62460.1 - 5.1 6.6 6.2 4.1 6.9 2.6 2.0 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Baculo_PEP_C PF04513.7 CDJ62460.1 - 7.3 6.4 10.3 15 5.4 2.9 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APC_CDC26 PF10471.4 CDJ62461.1 - 0.0084 16.8 8.0 0.57 10.9 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex APC subunit 1 DUF2156 PF09924.4 CDJ62461.1 - 0.11 11.2 0.5 0.47 9.2 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2156) Med15 PF09606.5 CDJ62461.1 - 0.32 9.1 21.6 0.44 8.6 14.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ62461.1 - 4.3 5.4 15.4 5 5.2 10.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mitofilin PF09731.4 CDJ62463.1 - 0.0012 17.5 12.0 0.0018 17.0 8.3 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein SR-25 PF10500.4 CDJ62463.1 - 0.011 15.2 12.7 0.018 14.5 8.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PSS PF03034.10 CDJ62463.1 - 0.018 14.4 0.3 0.045 13.1 0.0 1.7 1 1 1 2 2 2 0 Phosphatidyl serine synthase DUF4011 PF13195.1 CDJ62463.1 - 0.076 13.0 10.7 0.13 12.2 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) UCH PF00443.24 CDJ62463.1 - 0.096 11.7 6.6 0.11 11.6 4.6 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HlyD_2 PF12700.2 CDJ62463.1 - 0.19 10.8 7.2 0.22 10.6 5.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Peptidase_S64 PF08192.6 CDJ62463.1 - 0.56 8.4 6.8 0.72 8.1 4.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 eIF-3_zeta PF05091.7 CDJ62463.1 - 0.98 7.9 17.0 1.3 7.5 11.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Borrelia_P83 PF05262.6 CDJ62463.1 - 3.5 5.8 14.9 4.1 5.5 10.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 CDJ62463.1 - 3.6 5.7 48.7 4.9 5.2 33.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF940 PF06082.6 CDJ62463.1 - 5.2 5.5 10.6 6.9 5.0 7.3 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) XAP5 PF04921.9 CDJ62463.1 - 5.8 6.4 10.5 9.5 5.7 7.3 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator Tau95 PF09734.4 CDJ62463.1 - 6.4 5.9 12.3 8.5 5.5 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit BAF1_ABF1 PF04684.8 CDJ62464.1 - 0.0039 16.1 15.6 0.0039 16.1 10.8 7.4 4 2 3 7 7 7 1 BAF1 / ABF1 chromatin reorganising factor DAGK_acc PF00609.14 CDJ62466.1 - 7.4e-12 45.6 0.0 1.2e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CDJ62466.1 - 4.4e-09 35.8 7.6 3.5e-08 32.9 0.9 3.9 2 1 0 2 2 2 1 Diacylglycerol kinase catalytic domain Ribosomal_60s PF00428.14 CDJ62466.1 - 0.006 16.9 6.4 0.006 16.9 4.5 8.9 5 2 1 6 6 6 2 60s Acidic ribosomal protein Ycf4 PF02392.11 CDJ62466.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Ycf4 Phyto_Pns9_10 PF05878.6 CDJ62466.1 - 0.2 10.6 0.8 6.3 5.7 0.1 2.6 1 1 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 BAF1_ABF1 PF04684.8 CDJ62469.1 - 1.6e-06 27.2 24.1 2.2e-05 23.5 6.3 2.4 2 0 0 2 2 2 2 BAF1 / ABF1 chromatin reorganising factor DUF4175 PF13779.1 CDJ62469.1 - 0.075 10.7 28.1 0.059 11.0 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) PepSY_2 PF13670.1 CDJ62469.1 - 0.18 11.7 0.1 0.18 11.7 0.0 3.9 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain TCTP PF00838.12 CDJ62470.1 - 3.9e-45 153.8 1.6 4.5e-45 153.5 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein URO-D PF01208.12 CDJ62470.1 - 0.065 12.1 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) tRNA-synt_2b PF00587.20 CDJ62471.1 - 8e-32 110.1 0.1 1.1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CDJ62471.1 - 3.7e-21 75.1 1.5 3.7e-21 75.1 1.1 2.4 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Med15 PF09606.5 CDJ62471.1 - 0.0014 16.9 10.9 0.015 13.5 1.7 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.3 CDJ62471.1 - 0.013 14.5 5.9 0.2 10.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Pex14_N PF04695.8 CDJ62471.1 - 0.14 12.2 9.6 2.3 8.2 1.1 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAB3GAP2_N PF14655.1 CDJ62471.1 - 1.9 7.4 9.6 3.3 6.5 0.6 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4139 PF13598.1 CDJ62473.1 - 5.1 6.3 6.0 5.4 6.2 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) RNA_pol_Rpb8 PF03870.10 CDJ62474.1 - 2.4e-32 111.9 0.0 2.8e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Pkinase PF00069.20 CDJ62476.1 - 3.8e-61 206.5 0.0 9.3e-61 205.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62476.1 - 5e-30 104.4 0.0 1e-29 103.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase E1-E2_ATPase PF00122.15 CDJ62477.1 - 6.5e-56 188.9 0.0 1.3e-55 187.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDJ62477.1 - 9.5e-19 68.6 3.6 1e-13 52.1 0.1 4.2 3 2 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ62477.1 - 8.1e-10 39.1 0.0 3.9e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDJ62477.1 - 8.1e-07 28.9 0.0 0.014 15.3 0.0 2.7 2 0 0 2 2 2 2 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDJ62477.1 - 0.01 15.4 0.2 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Coiled-coil_56 PF09813.4 CDJ62478.1 - 3.9 7.5 6.9 1.2 9.1 1.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 DLIC PF05783.6 CDJ62479.1 - 0.53 8.9 3.0 1.1 7.9 2.1 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MIF4G_like_2 PF09090.6 CDJ62479.1 - 1.5 7.9 5.1 2.2 7.4 3.5 1.1 1 0 0 1 1 1 0 MIF4G like Exonuc_VII_L PF02601.10 CDJ62479.1 - 1.9 7.5 12.5 2.6 7.1 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ZYG-11_interact PF05884.7 CDJ62479.1 - 3.8 6.4 12.8 0.53 9.3 5.1 2.1 1 1 1 2 2 2 0 Interactor of ZYG-11 Spc7 PF08317.6 CDJ62479.1 - 6.3 5.3 11.3 8.8 4.8 7.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Melibiase PF02065.13 CDJ62479.1 - 6.9 5.2 6.3 8.8 4.9 4.4 1.1 1 0 0 1 1 1 0 Melibiase DUF4647 PF15504.1 CDJ62480.1 - 0.11 11.3 8.3 0.14 10.9 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) rve PF00665.21 CDJ62483.1 - 3.3e-13 49.7 0.8 2.1e-12 47.1 0.1 2.6 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.19 CDJ62483.1 - 3.1e-11 42.7 0.0 6.7e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_3 PF13456.1 CDJ62483.1 - 0.0067 16.1 0.0 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like GLTSCR1 PF15249.1 CDJ62483.1 - 0.058 13.5 0.2 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region DUF1539 PF07560.6 CDJ62483.1 - 0.09 12.6 0.1 0.26 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) RVT_1 PF00078.22 CDJ62484.1 - 3.4e-05 23.3 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 CDJ62486.1 - 4.9e-12 45.5 0.0 9.2e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62486.1 - 2.2e-10 40.0 0.0 4.7e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ62486.1 - 0.0016 17.5 0.0 0.003 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF4037 PF13228.1 CDJ62486.1 - 0.07 13.3 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) APH PF01636.18 CDJ62486.1 - 0.8 9.3 5.8 1.3 8.6 0.0 3.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family Radical_SAM PF04055.16 CDJ62487.1 - 0.0037 17.4 0.0 0.026 14.6 0.0 2.1 1 1 2 3 3 3 1 Radical SAM superfamily DUF4072 PF13284.1 CDJ62487.1 - 0.058 13.5 0.2 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) DUF908 PF06012.7 CDJ62488.1 - 6e-31 107.9 6.2 3.8e-25 88.9 0.1 4.0 4 0 0 4 4 4 3 Domain of Unknown Function (DUF908) DUF913 PF06025.7 CDJ62488.1 - 2.3e-09 36.4 11.3 5.2e-08 32.0 0.0 4.3 5 0 0 5 5 5 3 Domain of Unknown Function (DUF913) HECT PF00632.20 CDJ62489.1 - 1.7e-92 309.9 0.0 2.9e-92 309.2 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 CDJ62489.1 - 6.7e-11 42.0 1.3 1.2e-06 28.4 0.0 13.1 13 3 1 14 14 14 3 Domain of unknown function (DUF4414) UBA PF00627.26 CDJ62489.1 - 6.1e-09 35.4 0.0 1.8e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVT_1 PF00078.22 CDJ62492.1 - 1.5e-32 112.6 0.0 2.8e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CDJ62492.1 - 1.6e-05 25.0 0.0 4.7e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C2H2 PF00096.21 CDJ62492.1 - 0.013 15.8 0.9 0.013 15.8 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 CDJ62492.1 - 0.025 14.2 3.1 0.022 14.4 0.6 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MIF4G_like PF09088.6 CDJ62492.1 - 0.11 11.9 0.1 1.5 8.2 0.0 2.4 3 0 0 3 3 3 0 MIF4G like DUF2321 PF10083.4 CDJ62492.1 - 0.11 11.9 0.1 6.5 6.2 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_4 PF13894.1 CDJ62492.1 - 0.58 10.6 8.6 0.024 14.9 0.8 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger AAA_23 PF13476.1 CDJ62493.1 - 0.066 13.5 6.3 0.68 10.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF572 PF04502.8 CDJ62493.1 - 0.16 11.1 18.8 0.011 14.9 3.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4367 PF14285.1 CDJ62493.1 - 0.73 9.1 1.5 8.2 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) TFIIA PF03153.8 CDJ62493.1 - 4.1 7.2 32.9 1.4 8.7 7.1 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lactamase_B_2 PF12706.2 CDJ62494.1 - 7.3e-20 71.3 0.0 1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDJ62494.1 - 3.7e-06 26.7 0.0 0.0035 17.0 0.0 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Ribosomal_60s PF00428.14 CDJ62495.1 - 0.055 13.8 1.3 0.18 12.1 0.9 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 CDJ62495.1 - 0.2 10.5 0.5 0.26 10.0 0.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pro-rich PF15240.1 CDJ62496.1 - 0.097 12.7 35.1 0.13 12.3 24.3 1.1 1 0 0 1 1 1 0 Proline-rich PAT1 PF09770.4 CDJ62496.1 - 2.9 6.0 36.1 3.4 5.7 25.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ62496.1 - 3.8 7.3 28.5 4.8 6.9 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CarboxypepD_reg PF13620.1 CDJ62497.1 - 3.6e-05 23.7 0.0 0.00044 20.2 0.1 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CDJ62497.1 - 0.051 13.6 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) UPF0560 PF10577.4 CDJ62497.1 - 8.5 4.4 7.1 3.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DICT PF10069.4 CDJ62498.1 - 0.0018 17.7 0.2 0.0031 17.0 0.1 1.4 1 1 0 1 1 1 1 Sensory domain found in DIguanylate Cyclases & Two-component systems SR-25 PF10500.4 CDJ62498.1 - 0.025 14.0 7.0 0.048 13.1 4.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DOR PF14839.1 CDJ62498.1 - 0.81 9.3 5.5 0.24 11.1 0.3 2.1 2 0 0 2 2 2 0 DOR family DUF755 PF05501.6 CDJ62498.1 - 5.8 6.9 11.6 2.8 8.0 6.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF2232 PF09991.4 CDJ62500.1 - 5.5 5.8 1.8 17 4.2 1.2 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PAH PF02671.16 CDJ62501.1 - 0.065 12.8 6.7 5.1 6.7 0.1 3.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat Chromo PF00385.19 CDJ62502.1 - 6.3e-10 38.5 0.0 1.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDJ62503.1 - 3.2e-05 23.4 0.0 5.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDJ62503.1 - 0.0022 18.1 0.1 0.006 16.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF3552 PF12072.3 CDJ62503.1 - 0.29 10.3 0.5 0.47 9.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ATP_sub_h PF10775.4 CDJ62505.1 - 0.17 11.6 2.3 0.32 10.7 1.6 1.6 1 0 0 1 1 1 0 ATP synthase complex subunit h DUF3365 PF11845.3 CDJ62505.1 - 2.1 8.1 8.6 2.5 7.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) IncA PF04156.9 CDJ62506.1 - 0.00032 20.3 0.1 0.00032 20.3 0.1 4.1 2 1 0 2 2 2 1 IncA protein PRP1_N PF06424.7 CDJ62506.1 - 0.023 15.0 0.8 0.023 15.0 0.6 3.7 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal LMBR1 PF04791.11 CDJ62507.1 - 0.31 9.5 1.3 0.31 9.5 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1675 PF07897.6 CDJ62507.1 - 0.42 10.4 13.8 0.66 9.7 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PLRV_ORF5 PF01690.12 CDJ62507.1 - 0.6 9.1 7.5 0.58 9.2 5.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAPS PF04499.10 CDJ62507.1 - 0.71 8.4 6.5 0.75 8.3 4.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Trypan_glycop_C PF10659.4 CDJ62507.1 - 4.2 7.7 9.4 28 5.0 6.5 2.3 1 1 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain eIF-3_zeta PF05091.7 CDJ62507.1 - 5.4 5.5 15.2 6.9 5.1 10.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.5 CDJ62508.1 - 0.00058 18.2 8.6 0.00058 18.2 6.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF303 PF03629.13 CDJ62508.1 - 0.0062 15.7 0.8 0.0067 15.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF303) FimP PF09766.4 CDJ62508.1 - 0.012 14.7 2.1 0.013 14.5 1.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein Zn_peptidase PF04228.8 CDJ62508.1 - 0.021 14.0 4.6 0.024 13.8 3.2 1.0 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF3767 PF12597.3 CDJ62508.1 - 0.024 14.2 0.9 0.028 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF3801 PF12687.2 CDJ62508.1 - 0.034 13.7 2.3 0.043 13.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) RAB3GAP2_N PF14655.1 CDJ62508.1 - 0.037 13.0 4.2 0.037 13.0 2.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SHR3_chaperone PF08229.6 CDJ62508.1 - 0.041 12.8 4.5 0.058 12.3 3.1 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 DUF2852 PF11014.3 CDJ62508.1 - 0.067 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF212 PF02681.9 CDJ62508.1 - 0.08 12.6 0.1 0.095 12.4 0.1 1.1 1 0 0 1 1 1 0 Divergent PAP2 family Suf PF05843.9 CDJ62508.1 - 0.082 12.6 3.1 0.083 12.6 2.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDJ62508.1 - 0.12 11.7 5.7 0.15 11.4 3.9 1.2 1 0 0 1 1 1 0 Vta1 like AIF_C PF14721.1 CDJ62508.1 - 0.32 11.2 5.2 0.12 12.6 1.5 1.7 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Serinc PF03348.10 CDJ62508.1 - 0.36 9.4 2.6 0.39 9.3 1.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF788 PF05620.6 CDJ62508.1 - 0.47 10.2 2.3 0.66 9.8 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DivIC PF04977.10 CDJ62508.1 - 1.1 8.8 7.0 1.4 8.4 4.8 1.2 1 0 0 1 1 1 0 Septum formation initiator Apt1 PF10351.4 CDJ62508.1 - 1.3 7.8 7.2 1.5 7.6 5.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2201_N PF13203.1 CDJ62508.1 - 2 7.5 8.3 2.5 7.1 5.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain BAF1_ABF1 PF04684.8 CDJ62508.1 - 2.1 7.1 14.1 2.9 6.6 9.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.8 CDJ62508.1 - 2.8 7.9 13.8 0.87 9.6 3.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.1 CDJ62508.1 - 6.3 4.3 17.2 7.4 4.1 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spore_YtfJ PF09579.5 CDJ62508.1 - 6.8 6.6 5.9 19 5.2 0.7 2.3 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Ribosomal_60s PF00428.14 CDJ62509.1 - 0.0034 17.7 4.0 0.0034 17.7 2.8 8.4 6 2 2 8 8 8 1 60s Acidic ribosomal protein SET PF00856.23 CDJ62509.1 - 5.6 7.2 8.5 3.7 7.8 0.0 3.5 2 1 0 2 2 2 0 SET domain TUSC2 PF15000.1 CDJ62510.1 - 0.19 11.8 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor candidate 2 DUF2722 PF10846.3 CDJ62511.1 - 0.037 13.0 3.2 1.7 7.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.3 CDJ62511.1 - 0.23 10.7 4.6 2.2 7.5 0.6 2.1 2 0 0 2 2 2 0 Spt20 family APC_CDC26 PF10471.4 CDJ62511.1 - 8.9 7.1 20.8 1.5 9.6 1.6 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 LMBR1 PF04791.11 CDJ62512.1 - 1.6e-05 23.7 2.9 0.00057 18.5 0.0 2.9 1 1 0 3 3 3 2 LMBR1-like membrane protein TFIIA PF03153.8 CDJ62512.1 - 0.3 10.9 113.9 0.28 11.0 28.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit U1snRNP70_N PF12220.3 CDJ62513.1 - 0.061 13.6 15.5 0.12 12.6 10.7 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ycf1 PF05758.7 CDJ62513.1 - 0.14 9.8 7.7 0.18 9.4 5.4 1.2 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 CDJ62513.1 - 1.4 7.5 18.3 2.9 6.5 12.7 1.5 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 CDJ62513.1 - 1.9 6.0 11.7 3.2 5.3 8.1 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Baculo_PP31 PF05311.6 CDJ62513.1 - 4.3 6.5 13.9 13 4.9 9.6 1.8 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Band_3_cyto PF07565.8 CDJ62513.1 - 5.3 6.4 16.2 20 4.6 11.2 2.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.7 CDJ62513.1 - 6.8 5.1 15.8 12 4.3 10.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF966 PF06136.8 CDJ62514.1 - 2.7 7.3 5.5 3.2 7.0 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Med15 PF09606.5 CDJ62514.1 - 3.5 5.7 21.3 4.1 5.4 14.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kazal_1 PF00050.16 CDJ62515.1 - 1.6e-19 69.6 14.8 3.5e-11 42.9 4.2 3.3 2 0 0 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CDJ62515.1 - 8.6e-18 64.0 8.0 5e-11 42.3 1.2 4.7 4 0 0 4 4 4 2 Kazal-type serine protease inhibitor domain NUDIX_4 PF14815.1 CDJ62516.1 - 0.57 9.6 4.4 0.24 10.8 1.1 1.8 2 0 0 2 2 2 0 NUDIX domain APC_CDC26 PF10471.4 CDJ62516.1 - 8.6 7.1 12.7 1.3 9.8 0.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Synaptobrevin PF00957.16 CDJ62517.1 - 5.5e-24 83.5 0.3 5.5e-24 83.5 0.2 2.0 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 CDJ62517.1 - 3.2e-20 71.4 0.0 8.9e-20 70.0 0.0 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3446 PF11928.3 CDJ62517.1 - 0.14 12.3 8.6 15 5.8 7.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Sporozoite_P67 PF05642.6 CDJ62517.1 - 0.19 9.5 0.4 0.25 9.1 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen POM121 PF15229.1 CDJ62518.1 - 0.0058 16.0 8.8 0.0058 16.0 6.1 2.3 1 1 1 2 2 2 1 POM121 family DUF755 PF05501.6 CDJ62519.1 - 0.0018 18.3 10.1 0.0018 18.3 7.0 10.1 8 2 2 10 10 10 4 Domain of unknown function (DUF755) SR-25 PF10500.4 CDJ62521.1 - 0.00036 20.0 9.3 0.00036 20.0 6.5 6.2 3 1 2 6 6 6 4 Nuclear RNA-splicing-associated protein AAA_23 PF13476.1 CDJ62521.1 - 0.18 12.0 12.7 0.15 12.3 4.4 2.4 2 0 0 2 2 2 0 AAA domain DUF1455 PF07306.6 CDJ62522.1 - 0.27 11.3 2.8 0.29 11.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) DUF2217 PF10265.4 CDJ62523.1 - 0.56 8.9 19.5 0.63 8.7 13.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Plasmodium_Vir PF05795.6 CDJ62523.1 - 0.77 8.8 7.5 1 8.5 5.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF566 PF04484.7 CDJ62523.1 - 5.7 6.3 32.6 7.6 5.9 22.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) SLD3 PF08639.5 CDJ62523.1 - 5.8 5.4 19.9 6.4 5.2 13.8 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 IncA PF04156.9 CDJ62524.1 - 0.0032 17.0 5.7 0.004 16.7 3.9 1.2 1 0 0 1 1 1 1 IncA protein DUF3357 PF11837.3 CDJ62524.1 - 0.019 14.7 0.6 0.02 14.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Claudin_2 PF13903.1 CDJ62524.1 - 0.038 13.6 3.5 0.04 13.6 2.4 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 CDJ62524.1 - 0.1 12.9 0.2 0.13 12.6 0.2 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FHIPEP PF00771.15 CDJ62524.1 - 0.2 9.9 7.2 0.2 9.9 5.0 1.0 1 0 0 1 1 1 0 FHIPEP family RskA PF10099.4 CDJ62524.1 - 0.26 10.9 21.3 0.3 10.8 14.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CD20 PF04103.10 CDJ62524.1 - 0.29 11.0 1.0 0.32 10.9 0.7 1.1 1 0 0 1 1 1 0 CD20-like family Ctr PF04145.10 CDJ62524.1 - 0.56 10.2 2.6 0.63 10.0 1.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family VIT1 PF01988.14 CDJ62524.1 - 0.58 9.6 7.2 0.66 9.4 5.0 1.0 1 0 0 1 1 1 0 VIT family DUF533 PF04391.7 CDJ62524.1 - 0.66 9.3 21.1 0.67 9.2 14.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Spt20 PF12090.3 CDJ62524.1 - 0.85 8.9 9.0 0.74 9.1 6.3 1.1 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDJ62524.1 - 0.99 8.3 15.5 1 8.3 10.7 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF3450 PF11932.3 CDJ62524.1 - 1.3 8.2 21.4 1.4 8.1 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0164 PF03687.8 CDJ62524.1 - 1.4 7.3 5.4 1.6 7.2 3.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) FYDLN_acid PF09538.5 CDJ62524.1 - 1.8 9.2 4.8 2.1 8.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Suf PF05843.9 CDJ62524.1 - 1.9 8.1 11.3 1.7 8.2 7.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.1 CDJ62524.1 - 2.7 6.9 11.5 2.6 6.9 7.9 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Presenilin PF01080.12 CDJ62524.1 - 3.2 6.4 6.1 3 6.5 4.2 1.0 1 0 0 1 1 1 0 Presenilin R_equi_Vir PF05526.6 CDJ62524.1 - 3.4 7.2 13.0 3.8 7.1 9.0 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Pex14_N PF04695.8 CDJ62524.1 - 4.5 7.3 17.6 4.9 7.2 12.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AIF_C PF14721.1 CDJ62524.1 - 4.9 7.4 8.8 5.2 7.3 6.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3373 PF11853.3 CDJ62524.1 - 5.6 5.3 14.2 6 5.2 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) UPF0560 PF10577.4 CDJ62524.1 - 6.1 4.9 15.8 5.8 5.0 11.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 HRXXH PF13933.1 CDJ62524.1 - 6.3 6.1 8.5 7.1 5.9 5.9 1.0 1 0 0 1 1 1 0 Putative peptidase family ERF PF04404.7 CDJ62524.1 - 6.5 6.2 15.4 7.1 6.1 10.7 1.1 1 0 0 1 1 1 0 ERF superfamily Gag_spuma PF03276.9 CDJ62524.1 - 6.6 4.9 15.3 6.5 4.9 10.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Serinc PF03348.10 CDJ62524.1 - 7.2 5.2 8.0 7.1 5.2 5.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) eIF3_subunit PF08597.5 CDJ62524.1 - 7.2 6.0 14.1 7.3 6.0 9.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PAT1 PF09770.4 CDJ62524.1 - 9.7 4.2 21.7 9.4 4.3 15.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3464 PF11947.3 CDJ62524.1 - 9.9 5.6 7.9 11 5.5 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) SR-25 PF10500.4 CDJ62526.1 - 0.00017 21.1 11.2 0.00017 21.1 7.8 3.9 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein Collagen PF01391.13 CDJ62526.1 - 0.0038 16.7 25.7 0.0038 16.7 17.8 6.7 4 1 2 6 6 6 3 Collagen triple helix repeat (20 copies) BT1 PF03092.11 CDJ62527.1 - 6.6e-66 222.8 17.2 1.2e-65 221.9 11.9 1.5 1 1 0 1 1 1 1 BT1 family zf-CCCH PF00642.19 CDJ62529.1 - 2.3e-09 36.6 15.7 3.3e-06 26.6 0.2 4.1 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 CDJ62531.1 - 8.9e-20 70.1 0.0 7.1e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ62531.1 - 7.2e-11 41.9 0.0 0.00024 21.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ62531.1 - 0.00025 20.8 0.0 0.0051 16.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_HII PF01351.13 CDJ62532.1 - 0.51 9.9 6.9 0.05 13.2 1.2 1.9 3 0 0 3 3 3 0 Ribonuclease HII PRANC PF09372.5 CDJ62532.1 - 0.77 9.7 4.1 1.2 9.1 0.2 2.6 3 0 0 3 3 3 0 PRANC domain Chorein_N PF12624.2 CDJ62535.1 - 0.093 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal region of Chorein, a TM vesicle-mediated sorter Nucleoporin_FG PF13634.1 CDJ62536.1 - 0.0059 16.8 33.9 0.0059 16.8 23.5 6.0 1 1 3 5 5 5 1 Nucleoporin FG repeat region Inhibitor_I71 PF12628.2 CDJ62537.1 - 0.0078 15.8 0.0 0.022 14.4 0.0 1.6 2 0 0 2 2 2 1 Falstatin, cysteine peptidase inhibitor Inhibitor_I42 PF09394.5 CDJ62537.1 - 0.014 15.6 0.0 0.2 12.0 0.0 2.1 1 1 0 1 1 1 0 Chagasin family peptidase inhibitor I42 TMEM220 PF15071.1 CDJ62538.1 - 0.13 12.7 0.4 0.22 12.0 0.3 1.3 1 0 0 1 1 1 0 Transmembrane family 220, helix YL1 PF05764.8 CDJ62539.1 - 0.0017 18.0 2.3 0.0021 17.7 1.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop53 PF07767.6 CDJ62539.1 - 0.26 10.2 4.5 0.34 9.8 3.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 CDJ62539.1 - 1 7.1 6.2 1.3 6.8 4.3 1.0 1 0 0 1 1 1 0 Nop14-like family WWbp PF10349.4 CDJ62539.1 - 7.1 7.5 20.9 3.5 8.5 11.7 2.1 2 0 0 2 2 2 0 WW-domain ligand protein Pkinase_Tyr PF07714.12 CDJ62540.1 - 6.1e-21 74.6 0.0 1.1e-08 34.5 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.20 CDJ62540.1 - 3.7e-15 55.7 0.1 7e-07 28.6 0.0 3.6 4 0 0 4 4 4 3 Protein kinase domain SAM_2 PF07647.12 CDJ62540.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MORN PF02493.15 CDJ62540.1 - 0.096 12.4 0.2 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 MORN repeat CRT-like PF08627.5 CDJ62541.1 - 3.5e-09 36.6 4.4 3.6e-09 36.6 0.3 2.2 2 0 0 2 2 2 1 CRT-like DUF914 PF06027.7 CDJ62541.1 - 0.0019 17.1 1.4 0.0019 17.1 1.0 1.8 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Nol1_Nop2_Fmu PF01189.12 CDJ62544.1 - 1.3e-33 116.5 0.0 2e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CDJ62544.1 - 4.1e-10 39.4 0.0 2e-09 37.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ62544.1 - 1.9e-08 34.3 0.1 9.5e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ62544.1 - 5.4e-07 30.1 0.0 1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CDJ62544.1 - 2.4e-05 23.9 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fibrillarin PF01269.12 CDJ62544.1 - 0.00068 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin PUA PF01472.15 CDJ62544.1 - 0.0027 17.3 0.0 0.0068 16.1 0.0 1.7 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.14 CDJ62544.1 - 0.0028 17.6 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.15 CDJ62544.1 - 0.0031 16.5 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 CDJ62544.1 - 0.015 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CDJ62544.1 - 0.027 14.8 0.2 0.1 12.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 CDJ62544.1 - 0.072 12.4 0.0 0.2 11.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain MARVEL PF01284.18 CDJ62545.1 - 0.0076 16.0 8.1 0.0076 16.0 5.6 2.1 1 1 1 2 2 2 1 Membrane-associating domain DUF2422 PF10337.4 CDJ62545.1 - 0.035 12.9 7.1 0.043 12.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) YIEGIA PF14045.1 CDJ62545.1 - 0.65 8.5 2.7 0.46 9.0 0.6 1.6 1 1 1 2 2 2 0 YIEGIA protein Claudin_2 PF13903.1 CDJ62545.1 - 0.68 9.6 10.7 1 9.0 7.4 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Kinase-like PF14531.1 CDJ62546.1 - 7.3e-13 48.1 0.0 1.5e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDJ62546.1 - 1.6e-12 47.1 0.0 4.1e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62546.1 - 5.6e-07 28.8 0.0 9.5e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ62547.1 - 5.5e-10 38.6 0.1 3.1e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDJ62547.1 - 7.6e-06 25.2 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62547.1 - 0.0036 16.4 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Bromodomain PF00439.20 CDJ62548.1 - 3.8e-33 113.2 0.0 2.4e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 Bromodomain V_ATPase_I PF01496.14 CDJ62548.1 - 0.19 9.5 0.4 0.3 8.8 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med15 PF09606.5 CDJ62548.1 - 3.1 5.8 49.5 0.025 12.8 27.6 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spc24 PF08286.6 CDJ62548.1 - 3.8 7.2 8.4 8.4 6.1 5.8 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Rer1 PF03248.8 CDJ62549.1 - 8.7e-61 204.5 1.8 1.1e-60 204.2 1.3 1.1 1 0 0 1 1 1 1 Rer1 family FA_desaturase PF00487.19 CDJ62549.1 - 9.3 5.6 8.5 14 5.0 0.1 2.1 2 0 0 2 2 2 0 Fatty acid desaturase DUF726 PF05277.7 CDJ62551.1 - 6.4e-102 340.9 0.2 8.6e-102 340.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.17 CDJ62551.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 CDJ62551.1 - 0.0054 16.6 2.2 0.019 14.8 0.1 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDJ62551.1 - 0.0072 16.0 0.5 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family HpaB PF03241.8 CDJ62552.1 - 0.017 14.0 0.3 0.66 8.7 0.2 2.7 3 0 0 3 3 3 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Ku_PK_bind PF08785.6 CDJ62552.1 - 0.47 10.3 8.3 0.39 10.6 1.1 2.5 1 1 1 2 2 2 0 Ku C terminal domain like tRNA_edit PF04073.10 CDJ62553.1 - 2.8e-21 75.6 0.1 6.1e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 CDJ62553.1 - 1.5e-20 73.4 0.1 2.7e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CDJ62553.1 - 1.6e-18 66.3 0.0 5.3e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain ProRS-C_1 PF09180.6 CDJ62553.1 - 6.1e-15 54.8 0.0 2e-14 53.2 0.0 2.0 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal AP2 PF00847.15 CDJ62554.1 - 1.9e-05 24.7 1.0 0.015 15.4 0.5 2.5 2 0 0 2 2 2 2 AP2 domain zf-CCHC PF00098.18 CDJ62555.1 - 3e-05 23.7 3.6 3e-05 23.7 2.5 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ62555.1 - 0.0014 18.2 0.6 0.0014 18.2 0.4 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ62555.1 - 0.005 16.5 0.6 0.011 15.4 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ62555.1 - 0.023 14.3 0.5 0.046 13.4 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 CDJ62555.1 - 0.2 11.1 3.0 0.2 11.2 1.0 1.8 1 1 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 CDJ62556.1 - 2.8e-16 59.5 0.0 6.1e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDJ62557.1 - 5.8e-18 65.1 0.0 1.5e-17 63.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDJ62557.1 - 6.7e-10 38.4 0.0 1.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDJ62559.1 - 4.9e-16 58.9 0.0 1.6e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF3038 PF11237.3 CDJ62559.1 - 0.03 14.1 0.1 0.091 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) B12D PF06522.6 CDJ62561.1 - 0.028 14.1 0.1 0.079 12.6 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit FliJ PF02050.11 CDJ62561.1 - 0.18 11.8 3.9 5.6 7.0 0.0 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein DUF605 PF04652.11 CDJ62562.1 - 6.4 6.0 14.0 13 5.0 9.7 1.4 1 0 0 1 1 1 0 Vta1 like SQS_PSY PF00494.14 CDJ62563.1 - 0.0079 15.5 0.3 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Squalene/phytoene synthase DUF4135 PF13575.1 CDJ62563.1 - 0.26 10.2 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) WD40 PF00400.27 CDJ62565.1 - 2.6e-15 55.6 0.1 6.1e-05 22.7 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF605 PF04652.11 CDJ62566.1 - 0.027 13.9 28.2 0.0053 16.2 17.0 1.6 2 0 0 2 2 2 0 Vta1 like Med15 PF09606.5 CDJ62566.1 - 0.059 11.5 47.5 0.067 11.3 33.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ62566.1 - 0.085 11.0 38.2 0.1 10.8 26.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ62566.1 - 0.65 9.8 33.5 0.93 9.3 23.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.5 CDJ62566.1 - 1.5 7.1 19.2 0.48 8.7 11.8 1.3 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup gag-asp_proteas PF13975.1 CDJ62567.1 - 5.5e-09 35.7 0.0 1.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ62567.1 - 7.6e-09 35.9 0.0 2e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 CDJ62567.1 - 2.2e-05 24.2 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ62567.1 - 0.0013 18.6 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ62567.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Surface_antigen PF11054.3 CDJ62568.1 - 4e-98 327.8 9.1 4.5e-98 327.6 6.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Chromo PF00385.19 CDJ62569.1 - 9.2e-07 28.4 0.0 1.4e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Surface_antigen PF11054.3 CDJ62570.1 - 7.3e-98 326.9 4.1 8.1e-98 326.8 2.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62571.1 - 1.2e-95 319.7 5.0 1.3e-95 319.5 3.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen AJAP1_PANP_C PF15298.1 CDJ62571.1 - 0.024 14.5 2.6 0.051 13.4 1.8 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Surface_antigen PF11054.3 CDJ62572.1 - 3.8e-92 308.2 0.6 4.3e-92 308.0 0.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62573.1 - 1.2e-102 342.6 5.0 1.4e-102 342.4 3.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62574.1 - 5.7e-19 68.5 0.1 6.6e-19 68.2 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62575.1 - 3.9e-105 350.8 5.5 4.5e-105 350.6 3.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62576.1 - 2.5e-107 358.0 5.8 2.7e-107 357.8 4.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62577.1 - 9.6e-108 359.3 5.2 1.1e-107 359.2 3.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62578.1 - 8.8e-107 356.2 3.0 1e-106 356.0 2.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62579.1 - 5.9e-112 373.1 0.5 6.6e-112 373.0 0.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62580.1 - 3.8e-108 360.6 1.3 4.3e-108 360.5 0.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62581.1 - 2.5e-105 351.4 2.8 2.8e-105 351.2 1.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62582.1 - 0.00027 20.4 0.0 0.00028 20.3 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62583.1 - 7e-105 349.9 3.3 7.9e-105 349.8 2.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62584.1 - 8.3e-107 356.3 1.5 9.7e-107 356.0 1.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF2296 PF10058.4 CDJ62584.1 - 0.1 12.3 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Surface_antigen PF11054.3 CDJ62585.1 - 7.4e-109 363.0 3.3 8.4e-109 362.8 2.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62586.1 - 7.4e-106 353.1 1.5 8.4e-106 353.0 1.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62587.1 - 3.3e-113 377.2 4.9 3.7e-113 377.1 3.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Ycf1 PF05758.7 CDJ62588.1 - 0.63 7.6 7.5 0.26 8.9 3.7 1.5 2 0 0 2 2 2 0 Ycf1 Cellulose_synt PF03552.9 CDJ62588.1 - 1.8 6.7 2.9 3.2 5.9 2.0 1.4 1 0 0 1 1 1 0 Cellulose synthase DUF2232 PF09991.4 CDJ62588.1 - 3.4 6.5 6.7 6.2 5.7 4.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PLRV_ORF5 PF01690.12 CDJ62589.1 - 0.0059 15.8 16.1 0.008 15.3 11.1 1.2 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein Trypan_PARP PF05887.6 CDJ62589.1 - 0.015 15.1 4.9 0.016 15.0 3.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Lamp PF01299.12 CDJ62589.1 - 1 8.4 5.0 1.1 8.2 3.5 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Neisseria_TspB PF05616.8 CDJ62589.1 - 2.3 6.4 7.5 2.3 6.5 5.2 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Kinetochor_Ybp2 PF08568.5 CDJ62590.1 - 0.26 9.4 3.4 0.41 8.8 2.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin FimP PF09766.4 CDJ62590.1 - 0.38 9.7 23.4 8 5.4 1.0 3.1 3 0 0 3 3 3 0 Fms-interacting protein AAA_23 PF13476.1 CDJ62590.1 - 1.5 9.0 10.1 2.1 8.6 5.0 2.0 2 0 0 2 2 2 0 AAA domain Suf PF05843.9 CDJ62590.1 - 9.1 5.9 22.1 29 4.2 0.1 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PP2C PF00481.16 CDJ62591.1 - 4.1e-16 59.1 9.6 4.8e-06 26.1 0.0 4.6 4 0 0 4 4 4 3 Protein phosphatase 2C PAT1 PF09770.4 CDJ62591.1 - 0.00053 18.3 43.6 0.00053 18.3 30.2 4.2 4 0 0 4 4 4 2 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 CDJ62592.1 - 6.3e-66 222.1 0.0 1.2e-65 221.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62592.1 - 7.8e-32 110.3 0.0 9.9e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ62592.1 - 0.00064 18.7 0.0 0.0013 17.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CDJ62592.1 - 0.008 15.9 0.1 0.016 14.9 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDJ62592.1 - 0.011 14.7 0.1 0.021 13.9 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CDJ62592.1 - 0.026 13.8 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pex24p PF06398.6 CDJ62593.1 - 0.39 9.4 3.8 0.8 8.4 0.2 2.5 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Porin_3 PF01459.17 CDJ62594.1 - 1.1e-18 67.4 0.1 1.4e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin CAF-1_p150 PF11600.3 CDJ62596.1 - 0.00028 20.3 32.0 0.00028 20.3 22.2 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PixA PF12306.3 CDJ62596.1 - 0.0042 16.9 8.7 0.0042 16.9 6.0 2.3 2 1 1 3 3 3 1 Inclusion body protein MSA_2 PF00985.12 CDJ62596.1 - 0.12 12.5 27.6 0.22 11.6 19.1 1.4 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Pox_P4B PF03292.9 CDJ62596.1 - 0.4 8.5 12.2 0.49 8.2 8.5 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Macoilin PF09726.4 CDJ62596.1 - 2 6.5 22.9 3 6.0 15.9 1.4 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 CDJ62596.1 - 3.6 5.1 30.8 4.1 4.9 21.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AvrE PF11725.3 CDJ62596.1 - 4.3 4.2 28.4 4.5 4.1 19.7 1.1 1 0 0 1 1 1 0 Pathogenicity factor Dicty_REP PF05086.7 CDJ62596.1 - 5.9 4.5 18.1 6.9 4.2 12.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PRCC PF10253.4 CDJ62596.1 - 9.3 6.9 46.1 18 5.9 31.9 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Activator_LAG-3 PF11498.3 CDJ62597.1 - 6e-07 28.5 41.2 6e-07 28.5 28.6 9.8 7 2 2 9 9 9 1 Transcriptional activator LAG-3 Pkinase PF00069.20 CDJ62597.1 - 0.0031 16.7 8.2 0.0031 16.7 5.7 5.0 4 2 1 5 5 5 1 Protein kinase domain IncA PF04156.9 CDJ62598.1 - 2.5e-05 23.9 13.3 3.6e-05 23.4 9.2 1.2 1 0 0 1 1 1 1 IncA protein AAA_23 PF13476.1 CDJ62598.1 - 0.0027 18.0 1.5 0.0027 18.0 1.0 1.1 1 0 0 1 1 1 1 AAA domain VIT1 PF01988.14 CDJ62598.1 - 0.075 12.5 6.8 0.11 11.9 4.7 1.4 1 0 0 1 1 1 0 VIT family Herpes_gE PF02480.11 CDJ62598.1 - 0.088 11.0 0.2 0.097 10.9 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Macoilin PF09726.4 CDJ62598.1 - 0.1 10.9 14.3 0.11 10.7 9.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF726 PF05277.7 CDJ62598.1 - 0.12 11.2 2.8 0.14 11.0 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Shisa PF13908.1 CDJ62598.1 - 0.33 11.1 5.8 0.42 10.7 3.8 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator RAP1 PF07218.6 CDJ62598.1 - 0.47 8.4 4.4 0.5 8.4 3.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Serinc PF03348.10 CDJ62598.1 - 1.2 7.7 4.3 1.1 7.8 3.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) R_equi_Vir PF05526.6 CDJ62598.1 - 2 8.0 9.3 1.1 8.8 5.1 1.6 1 1 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF3551 PF12071.3 CDJ62598.1 - 7.7 6.1 11.8 16 5.0 7.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3551) Caudo_TAP PF02413.12 CDJ62599.1 - 0.019 15.1 2.4 0.02 15.0 1.7 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein SR-25 PF10500.4 CDJ62600.1 - 0.058 12.8 4.7 0.076 12.4 3.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein K_channel_TID PF07941.6 CDJ62600.1 - 0.37 11.0 4.4 0.86 9.8 3.1 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Chorion_2 PF03964.10 CDJ62600.1 - 3.1 8.4 12.7 5.5 7.6 8.8 1.7 1 1 0 1 1 1 0 Chorion family 2 OHA PF14418.1 CDJ62601.1 - 4e-12 45.4 5.4 6.2e-12 44.8 0.0 4.1 4 0 0 4 4 4 1 OST-HTH Associated domain AAR2 PF05282.6 CDJ62602.1 - 3.5e-53 180.8 0.0 1.1e-52 179.1 0.0 1.7 2 0 0 2 2 2 1 AAR2 protein IER PF05760.7 CDJ62602.1 - 1.4 8.7 28.4 0.063 13.1 4.4 3.1 3 0 0 3 3 3 0 Immediate early response protein (IER) Shadoo PF14999.1 CDJ62603.1 - 0.0011 18.8 0.2 0.0011 18.8 0.1 4.3 2 1 2 4 4 4 1 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDJ62603.1 - 0.039 14.3 56.7 1.4 9.4 3.7 4.4 4 0 0 4 4 4 0 60s Acidic ribosomal protein Suf PF05843.9 CDJ62603.1 - 4 7.0 7.5 0.7 9.5 1.0 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) rve PF00665.21 CDJ62605.1 - 1.8e-15 57.0 0.0 2.8e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Gcd10p PF04189.8 CDJ62606.1 - 5.9e-20 71.5 0.0 9.1e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family Tfb2 PF03849.9 CDJ62607.1 - 9.7e-09 34.3 0.0 0.005 15.5 0.0 3.1 3 0 0 3 3 3 3 Transcription factor Tfb2 Cyclin_N PF00134.18 CDJ62608.1 - 2.6e-13 49.6 0.1 3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 CDJ62608.1 - 0.0079 15.9 0.1 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat YfhO PF09586.5 CDJ62610.1 - 0.0023 16.0 2.8 0.0024 15.9 1.9 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO SprA-related PF12118.3 CDJ62610.1 - 0.0025 17.2 25.6 0.0032 16.8 17.7 1.2 1 0 0 1 1 1 1 SprA-related family CD20 PF04103.10 CDJ62610.1 - 0.0035 17.2 2.9 0.0079 16.1 2.0 1.6 1 1 0 1 1 1 1 CD20-like family DUF677 PF05055.7 CDJ62610.1 - 0.0047 15.6 0.7 0.0058 15.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Serinc PF03348.10 CDJ62610.1 - 0.013 14.2 7.1 0.015 14.0 4.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3413 PF11893.3 CDJ62610.1 - 0.021 13.7 9.4 0.029 13.2 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) VIT1 PF01988.14 CDJ62610.1 - 0.06 12.8 6.2 0.096 12.1 4.3 1.3 1 0 0 1 1 1 0 VIT family Med15 PF09606.5 CDJ62610.1 - 0.073 11.2 40.0 0.085 11.0 27.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDJ62610.1 - 0.085 13.1 9.1 0.11 12.7 6.3 1.2 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.8 CDJ62610.1 - 0.088 12.6 25.6 0.1 12.4 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YppG PF14179.1 CDJ62610.1 - 0.15 12.6 24.4 0.19 12.3 13.7 2.1 2 0 0 2 2 2 0 YppG-like protein DUF2232 PF09991.4 CDJ62610.1 - 0.15 11.0 9.2 0.21 10.5 6.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2910 PF11139.3 CDJ62610.1 - 0.21 10.6 6.1 0.34 10.0 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Presenilin PF01080.12 CDJ62610.1 - 0.21 10.3 6.2 0.25 10.1 4.3 1.1 1 0 0 1 1 1 0 Presenilin DUF1980 PF09323.5 CDJ62610.1 - 0.23 11.1 7.2 0.3 10.8 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PAT1 PF09770.4 CDJ62610.1 - 0.29 9.3 31.9 0.32 9.1 22.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4179 PF13786.1 CDJ62610.1 - 0.55 10.4 6.6 3.9 7.7 4.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) FLO_LFY PF01698.11 CDJ62610.1 - 0.77 8.5 8.3 0.97 8.2 5.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PRA1 PF03208.14 CDJ62610.1 - 0.98 8.7 3.7 0.71 9.1 0.6 1.9 1 1 1 2 2 2 0 PRA1 family protein Peptidase_C37 PF05416.7 CDJ62610.1 - 1.7 6.8 11.6 2.1 6.5 8.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase UPF0118 PF01594.11 CDJ62610.1 - 2 7.3 4.3 2.2 7.1 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF20 SID-1_RNA_chan PF13965.1 CDJ62610.1 - 2.3 6.2 5.7 2.9 5.9 3.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 CDJ62610.1 - 2.6 7.8 5.2 3.5 7.4 3.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDFI PF15316.1 CDJ62610.1 - 5.1 7.0 6.2 7.8 6.4 4.3 1.3 1 0 0 1 1 1 0 MyoD family inhibitor HemX PF04375.9 CDJ62610.1 - 7.1 5.1 32.3 9.4 4.7 22.4 1.1 1 0 0 1 1 1 0 HemX DUF912 PF06024.7 CDJ62610.1 - 8.3 6.5 9.1 2.9 8.0 3.9 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pescadillo_N PF06732.6 CDJ62611.1 - 1.3e-08 34.5 0.0 1.3e-08 34.5 0.0 4.6 3 2 1 4 4 4 2 Pescadillo N-terminus DUF3439 PF11921.3 CDJ62611.1 - 0.021 14.5 2.2 0.078 12.7 1.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Macoilin PF09726.4 CDJ62611.1 - 2.2 6.4 41.4 1.4 7.1 5.0 2.1 2 0 0 2 2 2 0 Transmembrane protein SR-25 PF10500.4 CDJ62611.1 - 3.9 6.8 56.6 5.6 6.3 28.7 3.0 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ62612.1 - 0.0015 17.7 8.1 0.0016 17.5 5.6 1.2 1 0 0 1 1 1 1 Fms-interacting protein Med15 PF09606.5 CDJ62612.1 - 0.0065 14.7 28.5 0.0076 14.5 19.8 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDJ62612.1 - 0.0066 15.2 3.2 0.0075 15.0 2.2 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Spt20 PF12090.3 CDJ62612.1 - 0.015 14.6 5.3 0.018 14.3 3.7 1.2 1 0 0 1 1 1 0 Spt20 family SpoVR PF04293.8 CDJ62612.1 - 0.017 13.5 2.3 0.017 13.4 1.6 1.1 1 0 0 1 1 1 0 SpoVR like protein PAT1 PF09770.4 CDJ62612.1 - 0.022 13.0 14.5 0.021 13.0 10.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDJ62612.1 - 0.032 13.9 7.3 0.036 13.8 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDJ62612.1 - 0.036 14.1 10.5 0.055 13.5 7.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF45 PF01863.12 CDJ62612.1 - 0.041 13.6 3.6 0.049 13.4 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 BRF1 PF07741.8 CDJ62612.1 - 0.055 13.6 6.6 0.084 13.1 4.5 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Activator_LAG-3 PF11498.3 CDJ62612.1 - 0.071 11.8 24.7 0.072 11.8 17.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FCP1_C PF09309.5 CDJ62612.1 - 0.1 11.8 4.4 0.14 11.4 3.1 1.3 1 0 0 1 1 1 0 FCP1, C-terminal MCR_alpha PF02249.12 CDJ62612.1 - 0.15 12.1 1.8 0.19 11.7 1.3 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DDHD PF02862.12 CDJ62612.1 - 0.2 11.3 3.3 0.22 11.2 2.3 1.1 1 0 0 1 1 1 0 DDHD domain Robl_LC7 PF03259.12 CDJ62612.1 - 0.25 10.9 2.6 0.5 9.9 1.8 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain Ctr PF04145.10 CDJ62612.1 - 0.32 11.0 1.9 0.42 10.6 1.3 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Mus7 PF09462.5 CDJ62612.1 - 0.39 9.5 7.6 0.39 9.4 5.2 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family DUF3499 PF12005.3 CDJ62612.1 - 0.78 9.9 7.1 0.1 12.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Shadoo PF14999.1 CDJ62612.1 - 0.85 9.4 6.8 4.2 7.2 4.0 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF3357 PF11837.3 CDJ62612.1 - 1 9.2 4.0 0.72 9.7 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Med13_N PF11597.3 CDJ62612.1 - 1 7.9 9.8 1.2 7.7 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Muted PF14942.1 CDJ62612.1 - 1.4 8.8 10.8 2 8.3 7.5 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein F-protein PF00469.15 CDJ62612.1 - 1.7 7.9 6.9 2.1 7.6 4.8 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef AIRC PF00731.15 CDJ62612.1 - 1.9 7.7 7.7 0.11 11.7 0.2 2.0 2 0 0 2 2 2 0 AIR carboxylase RED_N PF07808.8 CDJ62612.1 - 4.2 6.5 12.7 7.1 5.7 8.8 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region RAB3GAP2_N PF14655.1 CDJ62612.1 - 4.8 6.0 13.1 6.5 5.6 9.0 1.3 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_23 PF13476.1 CDJ62612.1 - 6.2 7.0 12.4 8.3 6.6 8.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3373 PF11853.3 CDJ62612.1 - 6.5 5.1 9.1 7.6 4.9 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) NifQ PF04891.7 CDJ62612.1 - 7.5 6.6 9.9 11 6.1 6.8 1.3 1 0 0 1 1 1 0 NifQ DUF1840 PF08895.6 CDJ62612.1 - 9.2 6.3 12.0 6.2 6.9 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) Myosin_head PF00063.16 CDJ62614.1 - 3e-101 339.5 6.8 2.3e-68 230.9 0.0 4.8 3 2 2 5 5 5 3 Myosin head (motor domain) WD40 PF00400.27 CDJ62614.1 - 4.5e-05 23.1 0.0 0.00044 20.0 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat IQ PF00612.22 CDJ62614.1 - 0.0012 18.3 37.9 0.026 14.1 0.7 6.1 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_5 PF07728.9 CDJ62614.1 - 0.0025 17.5 0.2 0.0077 15.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SR-25 PF10500.4 CDJ62614.1 - 0.0034 16.8 8.4 0.0034 16.8 5.8 6.5 6 0 0 6 6 6 2 Nuclear RNA-splicing-associated protein AAA PF00004.24 CDJ62614.1 - 3.1 8.0 0.0 3.1 8.0 0.0 3.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.17 CDJ62615.1 - 1.5e-38 131.7 0.0 2.8e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ62615.1 - 4.4e-18 65.8 0.3 1.2e-16 61.2 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 CDJ62615.1 - 5.8e-10 38.6 0.1 1.1e-09 37.7 0.0 1.5 2 0 0 2 2 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDJ62615.1 - 2.4e-06 26.8 2.0 8.3e-06 25.1 0.0 2.1 2 0 0 2 2 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDJ62615.1 - 1.5e-05 24.5 0.0 4.9e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDJ62615.1 - 0.0037 17.2 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CDJ62615.1 - 0.0071 15.5 0.0 0.0071 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 TSA PF03249.8 CDJ62615.1 - 0.014 13.9 0.7 0.014 13.9 0.5 2.9 2 1 0 2 2 1 0 Type specific antigen AAA_29 PF13555.1 CDJ62615.1 - 0.05 13.1 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain HN PF00423.14 CDJ62615.1 - 0.052 11.8 0.0 0.052 11.8 0.0 1.6 2 0 0 2 2 1 0 Haemagglutinin-neuraminidase AAA_16 PF13191.1 CDJ62615.1 - 0.081 12.9 0.1 0.081 12.9 0.1 2.6 2 1 0 2 2 1 0 AAA ATPase domain Ribosomal_60s PF00428.14 CDJ62615.1 - 0.66 10.4 12.9 0.16 12.4 2.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA_24 PF13479.1 CDJ62615.1 - 0.81 9.2 0.0 0.81 9.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain Hex_IIIa PF02455.11 CDJ62615.1 - 1.2 7.7 11.2 0.1 11.2 2.4 2.0 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) Zip PF02535.17 CDJ62615.1 - 1.2 8.0 5.8 1.2 8.0 1.0 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter ABC_tran PF00005.22 CDJ62615.1 - 1.5 9.1 9.3 52 4.1 6.4 2.6 1 1 0 1 1 1 0 ABC transporter DUF4614 PF15391.1 CDJ62615.1 - 2.6 7.7 19.0 0.14 11.8 3.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) PAT1 PF09770.4 CDJ62615.1 - 4.6 5.3 27.2 8.9 4.4 18.8 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ62615.1 - 6.2 6.6 24.5 0.93 9.3 12.7 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit G-alpha PF00503.15 CDJ62615.1 - 9.1 4.8 26.1 7.4 5.1 3.3 4.1 4 0 0 4 4 4 0 G-protein alpha subunit DUF2910 PF11139.3 CDJ62616.1 - 0.53 9.3 5.7 0.16 11.1 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) DUF1345 PF07077.6 CDJ62616.1 - 5.8 6.4 8.5 3.3 7.1 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Syja_N PF02383.13 CDJ62617.1 - 2e-28 99.1 0.0 2.5e-13 49.5 0.0 3.7 4 1 0 4 4 4 2 SacI homology domain AMP-binding PF00501.23 CDJ62618.1 - 8.6e-74 248.3 0.0 1.3e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Myc_target_1 PF15179.1 CDJ62619.1 - 1.1 8.8 11.3 1.6 8.2 0.1 2.8 3 0 0 3 3 3 0 Myc target protein 1 DUF572 PF04502.8 CDJ62620.1 - 0.042 13.0 20.5 0.065 12.4 14.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPX PF03105.14 CDJ62624.1 - 2.6e-29 102.8 0.8 2.6e-29 102.8 0.5 2.6 3 0 0 3 3 3 1 SPX domain DUF202 PF02656.10 CDJ62624.1 - 5.3e-12 45.7 5.8 5.3e-12 45.7 4.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF202) VTC PF09359.5 CDJ62624.1 - 5.8e-12 45.2 0.0 8.7e-07 28.2 0.0 2.4 2 0 0 2 2 2 2 VTC domain FixQ PF05545.6 CDJ62624.1 - 0.034 13.8 0.4 0.081 12.5 0.3 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF21 PF01595.15 CDJ62625.1 - 4.1e-25 88.1 9.2 4.1e-25 88.1 6.4 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF21 YrhC PF14143.1 CDJ62625.1 - 0.12 12.3 2.9 0.39 10.6 2.0 1.9 1 0 0 1 1 1 0 YrhC-like protein DUF1510 PF07423.6 CDJ62625.1 - 4.4 6.6 10.7 0.38 10.1 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Plasmodium_Vir PF05795.6 CDJ62626.1 - 1 8.5 3.4 2 7.5 2.4 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 CDJ62626.1 - 1.9 6.6 18.5 2.6 6.2 12.9 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF2338 PF10100.4 CDJ62626.1 - 2.5 6.3 5.2 3.7 5.7 3.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Serinc PF03348.10 CDJ62626.1 - 5.9 5.4 4.8 7.8 5.0 3.4 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Apc1 PF12859.2 CDJ62626.1 - 9.6 6.4 9.3 30 4.8 6.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 SprA-related PF12118.3 CDJ62627.1 - 0.002 17.4 18.6 0.002 17.4 12.9 2.2 2 0 0 2 2 2 1 SprA-related family adh_short PF00106.20 CDJ62628.1 - 3.2e-07 30.4 9.8 0.00019 21.3 0.0 2.9 2 1 1 3 3 3 2 short chain dehydrogenase CDK2AP PF09806.4 CDJ62628.1 - 0.00083 19.6 19.6 0.0015 18.7 10.2 2.2 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein KR PF08659.5 CDJ62628.1 - 0.0016 18.1 0.0 0.0016 18.1 0.0 2.4 2 1 1 3 3 1 1 KR domain CAF-1_p150 PF11600.3 CDJ62628.1 - 0.0046 16.3 1.3 0.0046 16.3 0.9 3.1 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spt20 PF12090.3 CDJ62628.1 - 0.007 15.7 7.7 0.55 9.5 0.7 2.5 2 0 0 2 2 2 2 Spt20 family RskA PF10099.4 CDJ62628.1 - 0.0081 15.9 2.8 0.0081 15.9 1.9 3.0 3 0 0 3 3 3 1 Anti-sigma-K factor rskA Polysacc_synt_2 PF02719.10 CDJ62628.1 - 0.012 14.5 0.4 0.034 13.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Med15 PF09606.5 CDJ62628.1 - 0.25 9.4 35.6 0.6 8.2 12.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDJ62628.1 - 0.29 10.1 13.5 0.26 10.2 1.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein Ribosomal_60s PF00428.14 CDJ62628.1 - 1.3 9.4 12.2 0.68 10.3 4.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sporozoite_P67 PF05642.6 CDJ62628.1 - 1.5 6.5 11.6 0.024 12.5 1.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RAB3GAP2_N PF14655.1 CDJ62628.1 - 3.4 6.5 12.8 5 6.0 2.5 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ACPS PF01648.15 CDJ62629.1 - 0.05 13.4 0.2 0.05 13.4 0.2 1.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily TraT PF05818.7 CDJ62629.1 - 0.082 12.3 3.7 0.097 12.0 2.5 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Aminotran_3 PF00202.16 CDJ62629.1 - 0.087 11.6 1.7 0.11 11.3 1.1 1.0 1 0 0 1 1 1 0 Aminotransferase class-III Peptidase_S15 PF02129.13 CDJ62629.1 - 0.32 10.3 8.6 0.43 9.9 6.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SbcCD_C PF13558.1 CDJ62629.1 - 0.33 10.8 1.8 0.44 10.4 0.1 1.9 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF4613 PF15390.1 CDJ62629.1 - 0.37 8.8 9.0 0.4 8.7 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) FLO_LFY PF01698.11 CDJ62629.1 - 0.6 8.9 7.2 0.67 8.7 5.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein IncA PF04156.9 CDJ62629.1 - 1.4 8.4 19.6 1.8 8.1 13.6 1.2 1 0 0 1 1 1 0 IncA protein TFIIA PF03153.8 CDJ62629.1 - 1.5 8.6 22.5 1.8 8.3 15.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAR1 PF03101.10 CDJ62629.1 - 2.3 8.8 7.4 0.32 11.5 1.9 1.8 2 0 0 2 2 2 0 FAR1 DNA-binding domain MarB PF13999.1 CDJ62629.1 - 10 5.8 8.3 0.34 10.5 0.2 2.2 2 0 0 2 2 2 0 MarB protein CAF-1_p150 PF11600.3 CDJ62630.1 - 0.027 13.8 19.1 0.062 12.6 13.3 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Flavi_NS4B PF01349.12 CDJ62630.1 - 0.072 12.0 0.2 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B SDA1 PF05285.7 CDJ62630.1 - 3.5 6.8 23.0 5.3 6.2 16.0 1.3 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 CDJ62630.1 - 5.4 4.5 10.3 8.5 3.9 7.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 CDJ62630.1 - 8.8 5.6 23.6 19 4.5 16.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDK2AP PF09806.4 CDJ62634.1 - 9e-05 22.7 13.2 9e-05 22.7 9.1 2.8 2 1 1 3 3 3 1 Cyclin-dependent kinase 2-associated protein APC_CDC26 PF10471.4 CDJ62634.1 - 0.054 14.2 12.4 0.38 11.5 3.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF4407 PF14362.1 CDJ62634.1 - 0.26 10.1 11.4 0.009 15.0 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spt20 PF12090.3 CDJ62634.1 - 0.75 9.1 4.0 1.4 8.2 0.7 2.0 2 0 0 2 2 2 0 Spt20 family PHD_3 PF13922.1 CDJ62634.1 - 1.2 9.4 8.7 1.5 9.1 1.2 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Suf PF05843.9 CDJ62634.1 - 1.8 8.2 4.2 4.9 6.8 1.8 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.1 CDJ62634.1 - 3.5 6.5 5.8 4.3 6.2 0.7 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF945 PF06097.6 CDJ62634.1 - 3.6 6.2 6.9 1.8 7.2 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF945) Sporozoite_P67 PF05642.6 CDJ62635.1 - 0.047 11.5 0.6 0.1 10.4 0.4 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SpoIIIAH PF12685.2 CDJ62635.1 - 0.27 10.6 0.0 0.27 10.6 0.0 1.9 3 0 0 3 3 3 0 SpoIIIAH-like protein Herpes_US9 PF06072.6 CDJ62635.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF4418 PF14387.1 CDJ62635.1 - 1.6 8.4 4.7 0.56 9.9 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) TBP PF00352.16 CDJ62636.1 - 1.6e-32 110.6 0.1 6.5e-15 54.2 0.0 3.2 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CDJ62636.1 - 0.0022 18.0 0.0 0.0031 17.5 0.0 3.8 5 0 0 5 5 5 2 Domain of unknown function (DUF3378) MSP1_C PF07462.6 CDJ62637.1 - 4.1 5.6 15.0 7.8 4.7 10.4 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TBPIP PF07106.8 CDJ62638.1 - 3e-21 75.6 0.2 6e-21 74.7 0.2 1.5 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 CDJ62638.1 - 0.00051 19.7 2.6 0.00072 19.2 1.8 1.3 1 0 0 1 1 1 1 Mnd1 family Glyco_hydro_67N PF03648.9 CDJ62638.1 - 0.024 14.6 0.9 0.1 12.6 0.0 2.4 1 1 2 3 3 3 0 Glycosyl hydrolase family 67 N-terminus EcoEI_R_C PF08463.5 CDJ62638.1 - 0.027 14.3 5.3 0.12 12.2 1.4 2.3 2 1 0 2 2 2 0 EcoEI R protein C-terminal SpoIIIAH PF12685.2 CDJ62638.1 - 0.059 12.8 8.3 0.1 12.1 5.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1827 PF08860.5 CDJ62638.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) Cytochrome-c551 PF10643.4 CDJ62638.1 - 0.21 10.8 3.2 0.28 10.4 0.1 2.0 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Lge1 PF11488.3 CDJ62638.1 - 0.28 11.3 2.4 0.23 11.6 0.3 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Phage_GP20 PF06810.6 CDJ62638.1 - 4.2 6.8 10.0 0.1 12.0 1.8 2.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 GAS PF13851.1 CDJ62638.1 - 9.1 5.4 12.1 1.1 8.3 5.6 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Etmic-2 PF06670.6 CDJ62641.1 - 2.9e-186 618.7 30.5 1.2e-184 613.4 21.1 2.0 1 1 0 1 1 1 1 Microneme protein Etmic-2 Synthase_beta PF11421.3 CDJ62642.1 - 9.1 7.0 14.8 1.6 9.4 0.0 3.6 3 0 0 3 3 3 0 ATP synthase F1 beta subunit Pkinase_Tyr PF07714.12 CDJ62643.1 - 0.0002 20.5 0.0 0.00031 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDJ62643.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain SNF2_N PF00176.18 CDJ62644.1 - 8e-71 238.2 0.0 1.1e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.1 CDJ62644.1 - 3.4e-08 33.3 8.0 7.5e-08 32.2 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ62644.1 - 6.5e-08 32.1 5.9 1.6e-07 30.9 4.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDJ62644.1 - 6.7e-07 28.8 5.5 1.4e-06 27.8 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDJ62644.1 - 3.2e-05 23.4 6.5 7.5e-05 22.3 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ62644.1 - 6.6e-05 22.6 8.7 0.00015 21.5 6.0 1.7 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 CDJ62644.1 - 0.0069 16.2 0.0 0.023 14.5 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-MIZ PF02891.15 CDJ62644.1 - 0.0075 15.7 7.0 0.017 14.5 4.8 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 CDJ62644.1 - 0.0083 15.9 8.1 0.02 14.7 5.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CDJ62644.1 - 0.034 13.9 2.3 0.087 12.6 1.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CDJ62644.1 - 0.071 12.8 6.6 0.18 11.5 4.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Zn-ribbon_8 PF09723.5 CDJ62644.1 - 0.23 11.4 1.4 2.1 8.3 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Peptidase_C48 PF02902.14 CDJ62646.1 - 7.4e-11 42.0 3.5 4.4e-10 39.5 2.4 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Kinesin PF00225.18 CDJ62648.1 - 2.5e-10 39.5 0.0 3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Ank_2 PF12796.2 CDJ62650.1 - 9.6e-06 25.8 0.1 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDJ62650.1 - 1.1e-05 25.4 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ62650.1 - 0.00012 21.9 0.0 0.15 12.3 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CDJ62650.1 - 0.00068 20.0 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CDJ62650.1 - 0.015 15.0 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Peptidase_M24 PF00557.19 CDJ62652.1 - 5.6e-56 189.3 0.0 9.2e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CDJ62652.1 - 2e-11 43.4 0.0 4.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain FBPase PF00316.15 CDJ62653.1 - 1.6e-67 227.6 0.0 1.8e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CDJ62653.1 - 0.08 12.2 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Inositol monophosphatase family DUF1264 PF06884.6 CDJ62654.1 - 0.089 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) SF-assemblin PF06705.6 CDJ62655.1 - 2.9e-36 124.8 18.1 4e-36 124.4 12.6 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin Ribosomal_L17 PF01196.14 CDJ62655.1 - 6.5e-09 36.2 3.9 1.7e-08 34.9 0.0 2.9 3 1 0 3 3 3 1 Ribosomal protein L17 Baculo_PEP_C PF04513.7 CDJ62655.1 - 0.019 14.7 9.2 0.21 11.4 0.3 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1019 PF06254.6 CDJ62655.1 - 4.5 7.4 8.8 1 9.5 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1019) AHH PF14412.1 CDJ62655.1 - 4.6 7.2 5.8 20 5.1 1.3 2.7 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Peptidase_C50 PF03568.12 CDJ62656.1 - 9.1e-05 21.2 0.0 0.00013 20.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 TPR_11 PF13414.1 CDJ62657.1 - 0.009 15.6 0.6 0.079 12.6 0.0 2.5 3 0 0 3 3 3 1 TPR repeat Peptidase_S8 PF00082.17 CDJ62660.1 - 7.2e-44 150.0 0.7 1.1e-43 149.3 0.5 1.2 1 0 0 1 1 1 1 Subtilase family EGF_CA PF07645.10 CDJ62660.1 - 2e-14 53.2 42.6 3.6e-09 36.4 4.5 4.6 4 1 1 5 5 5 3 Calcium-binding EGF domain EGF_3 PF12947.2 CDJ62660.1 - 3e-14 52.6 39.3 0.00015 21.6 7.3 4.4 4 0 0 4 4 4 4 EGF domain cEGF PF12662.2 CDJ62660.1 - 1e-11 44.2 12.4 1e-05 25.0 0.6 3.6 3 0 0 3 3 3 2 Complement Clr-like EGF-like EGF PF00008.22 CDJ62660.1 - 4.3e-05 23.3 36.5 0.048 13.6 2.8 4.5 4 0 0 4 4 4 4 EGF-like domain FXa_inhibition PF14670.1 CDJ62660.1 - 0.019 15.0 36.3 0.062 13.4 2.7 4.4 3 1 1 4 4 4 0 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CDJ62660.1 - 3.9 7.3 39.3 0.05 13.3 3.3 4.6 4 0 0 4 4 4 0 MSP1 EGF domain 1 V-SNARE_C PF12352.3 CDJ62661.1 - 1.5e-13 50.5 0.1 3.3e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CDJ62661.1 - 0.0035 16.9 0.0 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 Sec20 RP-C_C PF11800.3 CDJ62661.1 - 0.029 14.0 0.5 0.052 13.2 0.4 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1220 PF06758.8 CDJ62661.1 - 0.11 12.2 3.3 7.4 6.4 0.1 3.6 4 0 0 4 4 4 0 Repeat of unknown function (DUF1220) RRM_1 PF00076.17 CDJ62662.1 - 9.2e-06 25.2 0.1 3.1e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ62662.1 - 4.3e-05 23.4 0.1 0.00014 21.7 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ62662.1 - 0.015 15.1 0.1 0.033 14.0 0.1 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 CDJ62663.1 - 6.9e-25 86.5 2.2 1.2e-24 85.7 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CDJ62663.1 - 1.5e-21 76.0 0.1 1.6e-20 72.7 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CDJ62663.1 - 8.8e-13 48.1 16.3 8.8e-13 48.1 11.3 2.3 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 CDJ62663.1 - 0.017 14.7 10.4 0.16 11.6 0.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Tnp_zf-ribbon_2 PF13842.1 CDJ62663.1 - 6.3 7.2 10.6 21 5.6 0.1 3.5 2 1 1 3 3 3 0 DDE_Tnp_1-like zinc-ribbon HEAT PF02985.17 CDJ62664.1 - 6.8e-09 35.0 14.0 0.0046 16.9 0.1 7.1 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 CDJ62664.1 - 4.9e-08 33.1 10.0 0.0011 19.2 0.0 5.4 4 3 3 7 7 7 4 HEAT repeats Apt1 PF10351.4 CDJ62665.1 - 6 5.6 0.0 6 5.6 0.0 8.8 11 1 0 11 11 11 0 Golgi-body localisation protein domain DNA_mis_repair PF01119.14 CDJ62666.1 - 1.8e-25 88.6 0.0 4.1e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CDJ62666.1 - 5e-09 35.9 0.0 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CDJ62666.1 - 3.3e-07 30.0 0.0 1.2e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cmc1 PF08583.5 CDJ62667.1 - 0.00067 19.3 1.4 0.0012 18.5 1.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CDJ62667.1 - 0.35 10.9 2.3 16 5.6 0.0 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Mem_trans PF03547.13 CDJ62669.1 - 2.5e-05 22.7 1.0 0.00034 19.0 0.4 2.0 2 0 0 2 2 2 1 Membrane transport protein Spore_coat_CotO PF14153.1 CDJ62669.1 - 0.0001 21.8 24.6 0.00024 20.6 17.1 1.6 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 CDJ62669.1 - 0.00086 18.0 12.9 0.0012 17.5 8.6 1.5 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein PhoD PF09423.5 CDJ62669.1 - 0.0035 15.9 15.3 0.0035 15.9 10.6 3.0 1 1 1 2 2 1 1 PhoD-like phosphatase DUF605 PF04652.11 CDJ62669.1 - 0.0055 16.1 29.3 0.0055 16.1 20.3 2.1 2 0 0 2 2 2 1 Vta1 like PAT1 PF09770.4 CDJ62669.1 - 0.025 12.8 67.0 0.047 11.9 46.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 CDJ62669.1 - 0.026 13.1 2.2 0.04 12.5 1.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Otopetrin PF03189.8 CDJ62669.1 - 0.07 12.1 0.2 0.081 11.9 0.1 1.4 1 0 0 1 1 1 0 Otopetrin Ycf1 PF05758.7 CDJ62669.1 - 0.25 8.9 24.4 0.34 8.5 16.9 1.1 1 0 0 1 1 1 0 Ycf1 Herpes_UL87 PF03043.9 CDJ62669.1 - 1.7 6.9 10.0 2.7 6.2 6.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family TFIIA PF03153.8 CDJ62669.1 - 1.8 8.3 50.0 0.11 12.3 30.7 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.7 CDJ62669.1 - 2.3 6.7 30.1 4.3 5.8 20.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med15 PF09606.5 CDJ62669.1 - 2.9 5.9 89.0 4.7 5.2 61.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal KASH PF10541.4 CDJ62670.1 - 0.48 10.2 7.9 0.18 11.6 3.1 2.0 2 0 0 2 2 2 0 Nuclear envelope localisation domain TFIIA PF03153.8 CDJ62670.1 - 1.5 8.6 13.4 1.9 8.2 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 CDJ62672.1 - 0.59 7.7 5.4 0.61 7.7 3.7 1.1 1 0 0 1 1 1 0 Ycf1 Glycogen_syn PF05693.8 CDJ62672.1 - 2 6.5 6.0 2.9 6.0 4.1 1.2 1 0 0 1 1 1 0 Glycogen synthase OmpH PF03938.9 CDJ62672.1 - 2.6 7.9 29.3 0.11 12.3 13.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Nop25 PF09805.4 CDJ62672.1 - 3.4 7.7 19.1 0.69 9.9 8.1 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) VIT1 PF01988.14 CDJ62672.1 - 4.2 6.8 6.0 0.67 9.4 1.5 1.7 2 0 0 2 2 2 0 VIT family Mnd1 PF03962.10 CDJ62672.1 - 8.1 6.0 20.9 1 8.9 11.6 1.6 2 0 0 2 2 2 0 Mnd1 family DUF2937 PF11157.3 CDJ62672.1 - 8.4 5.6 13.6 21 4.3 9.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Coatomer_WDAD PF04053.9 CDJ62673.1 - 7e-94 315.1 0.0 3.5e-77 260.1 0.0 2.3 2 1 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.27 CDJ62673.1 - 2.5e-05 23.9 0.1 0.0041 16.9 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat RVT_1 PF00078.22 CDJ62674.1 - 7.8e-13 48.2 0.0 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CDJ62675.1 - 0.013 15.5 0.3 0.073 13.1 0.1 2.3 1 1 0 1 1 1 0 Retrotransposon gag protein Med15 PF09606.5 CDJ62679.1 - 0.12 10.5 58.9 0.11 10.6 40.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 CDJ62679.1 - 0.57 10.0 24.7 0.71 9.7 17.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.1 CDJ62679.1 - 0.69 7.5 61.1 0.81 7.3 42.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDJ62679.1 - 1.5 6.9 51.9 1.8 6.7 35.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ62679.1 - 2.9 7.6 44.2 3.2 7.5 30.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 CDJ62679.1 - 5.3 4.9 32.0 7 4.5 22.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Adeno_hexon PF01065.14 CDJ62679.1 - 5.6 5.6 16.9 6.2 5.5 11.7 1.0 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Mem_trans PF03547.13 CDJ62679.1 - 6.4 4.9 13.2 7.6 4.7 9.1 1.3 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 CDJ62679.1 - 6.9 4.2 32.6 8 4.0 22.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.5 CDJ62679.1 - 9.4 5.3 37.4 14 4.7 25.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DEAD PF00270.24 CDJ62680.1 - 1.1e-40 138.9 0.0 1.6e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 CDJ62680.1 - 8.2e-06 25.4 0.6 2.9e-05 23.7 0.1 2.0 1 1 1 2 2 2 1 Part of AAA domain ResIII PF04851.10 CDJ62680.1 - 0.0025 17.6 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CDJ62680.1 - 0.0039 16.8 0.0 0.014 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 CDJ62680.1 - 0.023 13.7 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CDJ62680.1 - 0.13 12.3 0.3 0.92 9.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain RCC1_2 PF13540.1 CDJ62681.1 - 2.3e-23 81.2 14.5 1.3e-07 31.0 0.0 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CDJ62681.1 - 1e-21 76.8 22.4 4e-07 30.1 0.1 7.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 CDJ62681.1 - 0.17 11.3 0.2 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Putative carbohydrate binding domain UTP15_C PF09384.5 CDJ62682.1 - 2.5e-07 30.5 0.4 3.2e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 UTP15 C terminal Utp12 PF04003.7 CDJ62682.1 - 0.011 15.6 1.1 0.012 15.4 0.8 1.1 1 0 0 1 1 1 0 Dip2/Utp12 Family MutS_III PF05192.13 CDJ62682.1 - 0.13 12.0 0.4 0.13 12.0 0.3 1.1 1 0 0 1 1 1 0 MutS domain III VirE_N PF08800.5 CDJ62683.1 - 0.018 14.7 0.1 0.064 13.0 0.0 1.9 1 1 0 1 1 1 0 VirE N-terminal domain Pex16 PF08610.5 CDJ62683.1 - 0.07 12.1 5.3 0.086 11.8 3.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Hid1 PF12722.2 CDJ62683.1 - 0.18 9.4 8.2 0.19 9.3 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.5 CDJ62683.1 - 1.3 8.1 16.6 2.3 7.3 11.5 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paramyxo_ncap PF00973.14 CDJ62683.1 - 3.4 6.2 10.9 5.6 5.5 7.5 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1675 PF07897.6 CDJ62683.1 - 5 6.9 13.5 9 6.0 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PAS PF00989.19 CDJ62683.1 - 5.6 6.7 6.3 6.9 6.4 1.3 2.3 2 0 0 2 2 2 0 PAS fold Jun PF03957.8 CDJ62684.1 - 0.14 11.8 3.6 0.15 11.7 2.5 1.0 1 0 0 1 1 1 0 Jun-like transcription factor Suf PF05843.9 CDJ62684.1 - 1.1 8.9 6.1 0.93 9.1 4.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-H2C2_2 PF13465.1 CDJ62685.1 - 0.006 16.8 0.8 0.006 16.8 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CDJ62685.1 - 0.024 14.9 1.2 0.052 13.9 0.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-Di19 PF05605.7 CDJ62685.1 - 0.052 13.6 0.3 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.2 CDJ62685.1 - 0.092 12.7 3.5 0.1 12.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-binding TFIIA PF03153.8 CDJ62685.1 - 1 9.1 10.7 1.2 9.0 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dus PF01207.12 CDJ62687.1 - 0.00038 19.3 0.0 0.00093 18.1 0.0 1.7 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PSD5 PF07637.6 CDJ62687.1 - 0.051 13.6 0.1 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) zf-CCCH PF00642.19 CDJ62687.1 - 0.071 12.8 12.0 0.21 11.3 8.3 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RPA_C PF08784.6 CDJ62687.1 - 3.6 8.0 0.0 3.6 8.0 0.0 3.1 2 1 1 3 3 3 0 Replication protein A C terminal NOB1_Zn_bind PF08772.6 CDJ62688.1 - 3.5e-19 68.4 0.8 5.5e-19 67.7 0.5 1.3 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN PF01850.16 CDJ62688.1 - 0.029 14.6 0.1 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 PIN domain zf-ribbon_3 PF13248.1 CDJ62688.1 - 0.066 12.4 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CDJ62688.1 - 0.12 12.0 1.1 0.23 11.1 0.8 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.6 CDJ62688.1 - 0.12 11.8 1.7 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 CDJ62688.1 - 0.13 11.9 1.3 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal TFIIA PF03153.8 CDJ62688.1 - 5.9 6.6 19.6 3.7 7.3 4.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3947 PF13135.1 CDJ62688.1 - 9.5 6.5 8.9 14 5.9 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) HEAT PF02985.17 CDJ62689.1 - 0.13 12.4 9.8 8.2 6.7 0.2 6.4 5 0 0 5 5 5 0 HEAT repeat EF-hand_8 PF13833.1 CDJ62690.1 - 6.3e-09 35.3 1.1 1.8e-08 33.8 0.8 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CDJ62690.1 - 2.5e-07 30.7 0.5 1.2e-06 28.5 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CDJ62690.1 - 1.9e-06 26.7 0.9 0.00079 18.5 0.3 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CDJ62690.1 - 0.00026 20.6 0.1 0.049 13.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CDJ62690.1 - 0.026 13.8 0.1 0.095 12.0 0.1 2.0 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.2 CDJ62690.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand ketoacyl-synt PF00109.21 CDJ62691.1 - 7.3e-18 64.9 0.0 1.4e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MIP-T3 PF10243.4 CDJ62692.1 - 0.033 12.6 75.1 0.035 12.5 52.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 CDJ62692.1 - 0.051 11.8 62.9 0.06 11.5 43.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Daxx PF03344.10 CDJ62692.1 - 9.3 4.5 61.2 12 4.2 42.4 1.0 1 0 0 1 1 1 0 Daxx Family Orbi_VP6 PF01516.11 CDJ62694.1 - 0.036 13.1 1.7 0.04 12.9 1.2 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Draxin PF15550.1 CDJ62694.1 - 0.081 12.5 7.7 0.1 12.2 5.3 1.2 1 0 0 1 1 1 0 Draxin CDC45 PF02724.9 CDJ62694.1 - 0.16 9.9 5.3 0.16 9.9 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.8 CDJ62694.1 - 0.4 10.1 8.2 0.44 10.0 5.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sporozoite_P67 PF05642.6 CDJ62694.1 - 0.45 8.3 2.8 0.49 8.2 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MIP-T3 PF10243.4 CDJ62694.1 - 1.3 7.3 23.2 1.5 7.1 16.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDK5_activator PF03261.10 CDJ62694.1 - 2.1 7.5 11.8 2.5 7.3 8.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Neur_chan_memb PF02932.11 CDJ62694.1 - 2.7 7.8 8.7 2.8 7.7 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PIG-S PF10510.4 CDJ62694.1 - 3.2 6.3 8.9 3.4 6.2 6.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Hid1 PF12722.2 CDJ62694.1 - 3.6 5.1 10.7 3.7 5.1 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LCD1 PF09798.4 CDJ62694.1 - 3.8 5.3 10.0 4.3 5.1 7.0 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3984 PF13136.1 CDJ62694.1 - 5.4 6.1 10.9 7 5.7 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4045 PF13254.1 CDJ62694.1 - 5.7 6.1 16.4 6.4 5.9 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Opi1 PF08618.5 CDJ62694.1 - 6.1 5.6 15.2 6.9 5.4 10.5 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 Zip PF02535.17 CDJ62694.1 - 8.8 5.2 11.5 12 4.7 8.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DEAD PF00270.24 CDJ62695.1 - 1.9e-05 24.2 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ras PF00071.17 CDJ62696.1 - 9.6e-16 57.5 0.3 1.1e-15 57.3 0.2 1.1 1 0 0 1 1 1 1 Ras family LppC PF04348.8 CDJ62696.1 - 0.04 12.4 0.4 0.048 12.2 0.3 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein YagB_YeeU_YfjZ PF06154.6 CDJ62696.1 - 0.076 13.2 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 YagB/YeeU/YfjZ family rve PF00665.21 CDJ62697.1 - 3.8e-21 75.4 0.0 1e-20 74.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDJ62697.1 - 8e-16 58.0 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDJ62697.1 - 1.2e-11 44.1 0.0 2.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.1 CDJ62697.1 - 1.4e-07 31.2 0.0 4.6e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ62697.1 - 4.4e-07 30.2 0.0 9.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDJ62697.1 - 1.8e-05 24.5 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ62697.1 - 0.013 15.4 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.5 CDJ62697.1 - 0.022 14.1 0.9 0.046 13.1 0.6 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger RVT_3 PF13456.1 CDJ62697.1 - 0.036 13.8 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Asp_protease PF09668.5 CDJ62697.1 - 0.073 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Myosin_head PF00063.16 CDJ62698.1 - 7.1e-11 40.8 0.0 9.1e-11 40.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Utp12 PF04003.7 CDJ62699.1 - 0.07 13.0 0.9 0.78 9.6 0.6 2.3 1 1 0 1 1 1 0 Dip2/Utp12 Family RAB3GAP2_N PF14655.1 CDJ62700.1 - 2.2 7.1 7.5 1.8 7.4 4.1 1.8 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_60s PF00428.14 CDJ62701.1 - 0.089 13.2 34.2 0.18 12.1 1.6 3.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein DnaJ PF00226.26 CDJ62703.1 - 4.9e-29 99.8 0.9 4.9e-29 99.8 0.6 1.7 2 0 0 2 2 2 1 DnaJ domain APP_E2 PF12925.2 CDJ62703.1 - 0.0086 15.6 0.5 0.016 14.7 0.3 1.4 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein GHMP_kinases_N PF00288.21 CDJ62703.1 - 0.02 14.9 0.2 0.02 14.9 0.1 2.1 2 0 0 2 2 2 0 GHMP kinases N terminal domain COX4 PF02936.9 CDJ62703.1 - 0.02 14.6 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF1217 PF06748.7 CDJ62703.1 - 0.078 13.0 0.8 0.94 9.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1217) Transposase_24 PF03004.9 CDJ62703.1 - 1.8 8.4 0.0 1.8 8.4 0.0 3.2 3 1 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) SR-25 PF10500.4 CDJ62703.1 - 2.3 7.6 13.9 0.34 10.3 5.6 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CDJ62703.1 - 9.1 6.4 11.8 0.28 11.4 0.5 2.0 1 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein FA_hydroxylase PF04116.8 CDJ62704.1 - 6.4e-11 42.6 15.8 1.2e-10 41.7 10.9 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.23 CDJ62704.1 - 4e-10 39.3 0.0 7.3e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OTCace_N PF02729.16 CDJ62705.1 - 4.6e-34 117.1 0.4 6.4e-32 110.1 0.0 4.1 3 1 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CDJ62705.1 - 1.5e-27 96.4 10.2 2.5e-27 95.6 0.0 5.2 3 2 2 5 5 5 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF1635 PF07795.6 CDJ62705.1 - 0.0041 16.5 6.8 0.0041 16.5 4.7 9.6 6 2 4 11 11 11 1 Protein of unknown function (DUF1635) DUF2215 PF10225.4 CDJ62706.1 - 0.053 12.9 0.1 0.053 12.9 0.0 3.8 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2215) TAF1D PF15333.1 CDJ62709.1 - 0.017 14.9 8.4 0.02 14.6 5.8 1.0 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D CAF-1_p150 PF11600.3 CDJ62709.1 - 0.034 13.5 16.9 0.041 13.2 11.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4603 PF15376.1 CDJ62709.1 - 0.064 10.4 14.1 0.078 10.1 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SprA-related PF12118.3 CDJ62709.1 - 0.065 12.5 21.0 0.094 12.0 14.5 1.2 1 0 0 1 1 1 0 SprA-related family CDK5_activator PF03261.10 CDJ62709.1 - 0.22 10.8 15.5 0.22 10.7 10.8 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF737 PF05300.6 CDJ62709.1 - 0.86 9.5 12.9 0.98 9.3 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF737) PsiA PF06952.6 CDJ62709.1 - 0.91 8.5 9.1 1 8.3 6.3 1.0 1 0 0 1 1 1 0 PsiA protein SHR3_chaperone PF08229.6 CDJ62709.1 - 0.93 8.4 6.7 0.99 8.3 4.6 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Peptidase_S49_N PF08496.5 CDJ62709.1 - 0.98 9.1 6.2 1.1 8.9 4.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 CDJ62709.1 - 1 7.9 6.8 1.2 7.7 4.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Acyl-thio_N PF12590.3 CDJ62709.1 - 1.3 9.4 10.2 1.7 9.1 7.1 1.0 1 0 0 1 1 1 0 Acyl-ATP thioesterase SelP_N PF04592.9 CDJ62709.1 - 1.5 8.1 16.7 1.6 8.0 11.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1675 PF07897.6 CDJ62709.1 - 2.2 8.0 15.5 2.4 7.9 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Raftlin PF15250.1 CDJ62709.1 - 3.1 6.2 14.1 3.6 6.0 9.8 1.0 1 0 0 1 1 1 0 Raftlin Zip PF02535.17 CDJ62709.1 - 3.8 6.4 13.5 4.5 6.1 9.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TCP PF03634.8 CDJ62709.1 - 4.1 7.7 16.0 5.4 7.3 11.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor BAF1_ABF1 PF04684.8 CDJ62709.1 - 5 5.8 29.1 4.9 5.8 20.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spc7_N PF15402.1 CDJ62709.1 - 5.5 4.8 17.6 7.8 4.3 12.2 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FlgH PF02107.11 CDJ62709.1 - 5.6 6.5 10.0 9.1 5.8 6.9 1.4 1 1 0 1 1 1 0 Flagellar L-ring protein DUF4175 PF13779.1 CDJ62709.1 - 6.8 4.2 27.4 7.2 4.1 19.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Helicase_C PF00271.26 CDJ62710.1 - 5.9e-10 38.8 0.5 3.1e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NPFF PF15085.1 CDJ62710.1 - 0.0044 17.2 7.1 0.0081 16.4 4.9 1.4 1 0 0 1 1 1 1 Neuropeptide FF DUF2722 PF10846.3 CDJ62710.1 - 0.0081 15.2 2.1 0.0098 14.9 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) 7tm_2 PF00002.19 CDJ62710.1 - 0.066 12.2 0.6 0.095 11.7 0.4 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Apc5 PF12862.2 CDJ62710.1 - 0.081 12.7 1.2 0.18 11.6 0.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 RAB3GAP2_N PF14655.1 CDJ62710.1 - 0.083 11.8 3.6 0.1 11.6 2.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDJ62710.1 - 0.2 9.8 11.7 0.22 9.7 8.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal G0-G1_switch_2 PF15103.1 CDJ62710.1 - 1.1 9.5 4.9 11 6.3 0.0 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 Adeno_E4_34 PF04528.8 CDJ62710.1 - 2.9 7.4 5.9 4.8 6.7 4.1 1.3 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Y_phosphatase3C PF13348.1 CDJ62711.1 - 3.3 7.8 5.6 1.5 8.9 0.6 2.7 2 0 0 2 2 2 0 Tyrosine phosphatase family C-terminal region LZ_Tnp_IS66 PF13007.2 CDJ62715.1 - 2.8 8.6 8.9 1.7 9.3 2.9 2.8 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain PGI PF00342.14 CDJ62718.1 - 1.2e-180 601.0 0.4 3.4e-119 398.4 0.0 2.1 2 0 0 2 2 2 2 Phosphoglucose isomerase DUF755 PF05501.6 CDJ62718.1 - 0.00035 20.6 18.0 0.00035 20.6 12.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF755) SR-25 PF10500.4 CDJ62718.1 - 0.054 12.9 16.7 0.14 11.5 11.6 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ62718.1 - 0.065 12.2 6.5 0.13 11.3 4.5 1.4 1 0 0 1 1 1 0 Fms-interacting protein DUF2217 PF10265.4 CDJ62718.1 - 0.11 11.2 8.8 0.24 10.1 4.8 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Pap_E4 PF02711.9 CDJ62718.1 - 0.17 12.7 3.6 0.37 11.6 2.5 1.5 1 0 0 1 1 1 0 E4 protein CDK2AP PF09806.4 CDJ62718.1 - 0.21 11.8 12.4 0.39 10.9 8.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DNA_pol_viral_N PF00242.12 CDJ62718.1 - 2.4 7.0 11.6 3.9 6.3 8.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Neur_chan_memb PF02932.11 CDJ62718.1 - 3.5 7.4 5.9 0.73 9.6 1.4 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 CDJ62718.1 - 4.5 5.3 18.8 6.8 4.7 13.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DAO PF01266.19 CDJ62719.1 - 1.4e-08 34.0 0.0 5.9e-08 32.0 0.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase GTP_EFTU_D3 PF03143.12 CDJ62720.1 - 1.1e-25 89.6 0.0 1.3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PTS_2-RNA PF01885.11 CDJ62721.1 - 1.1e-35 122.6 0.0 5.5e-28 97.5 0.0 2.7 2 1 0 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family RAB3GAP2_N PF14655.1 CDJ62721.1 - 0.12 11.3 1.7 0.2 10.6 1.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Coatomer_WDAD PF04053.9 CDJ62721.1 - 0.32 9.7 1.9 0.5 9.1 1.3 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Med15 PF09606.5 CDJ62722.1 - 0.41 8.7 41.7 0.55 8.3 28.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ62722.1 - 8.2 6.8 11.4 0.82 10.1 3.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein PT PF04886.7 CDJ62724.1 - 6.5e-05 22.1 6.7 6.5e-05 22.1 4.7 3.1 3 0 0 3 3 3 2 PT repeat Spore_coat_CotO PF14153.1 CDJ62724.1 - 0.001 18.5 3.9 0.001 18.5 2.7 1.7 2 0 0 2 2 2 1 Spore coat protein CotO Ribosomal_60s PF00428.14 CDJ62724.1 - 1.2 9.5 38.5 0.1 13.0 6.2 4.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Hom_end_hint PF05203.11 CDJ62724.1 - 4.3 7.0 5.9 8.5 6.0 4.1 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint DUF374 PF04028.8 CDJ62725.1 - 0.012 14.8 0.2 0.09 12.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF374) Actin PF00022.14 CDJ62726.1 - 6.1e-40 136.8 0.7 3.2e-19 68.6 0.0 3.3 2 1 1 3 3 3 3 Actin Spt20 PF12090.3 CDJ62726.1 - 0.21 10.9 3.9 21 4.4 0.0 3.3 3 0 0 3 3 3 0 Spt20 family Peptidase_C1 PF00112.18 CDJ62726.1 - 0.54 10.1 6.8 2 8.2 1.2 2.7 2 0 0 2 2 2 0 Papain family cysteine protease Carboxyl_trans PF01039.17 CDJ62727.1 - 0.089 11.1 3.6 0.1 10.9 2.5 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain Glyco_trans_2_3 PF13632.1 CDJ62728.1 - 0.084 12.5 2.9 0.17 11.5 2.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Ycf1 PF05758.7 CDJ62728.1 - 1.9 6.0 4.0 0.29 8.8 0.1 1.5 2 0 0 2 2 2 0 Ycf1 Activator_LAG-3 PF11498.3 CDJ62729.1 - 0.023 13.4 33.6 0.024 13.4 1.6 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Spt20 PF12090.3 CDJ62729.1 - 0.38 10.0 12.9 1.6 8.0 3.1 2.2 2 0 0 2 2 2 0 Spt20 family FDF PF09532.5 CDJ62729.1 - 0.56 10.7 12.3 1 9.8 3.6 2.3 2 0 0 2 2 2 0 FDF domain DUF4259 PF14078.1 CDJ62729.1 - 1.6 9.2 9.9 14 6.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) Zip PF02535.17 CDJ62729.1 - 2 7.3 5.3 15 4.5 3.7 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter SprA-related PF12118.3 CDJ62729.1 - 2.8 7.1 43.0 3.8 6.7 9.7 2.1 2 0 0 2 2 2 0 SprA-related family FimP PF09766.4 CDJ62729.1 - 3.2 6.7 20.2 0.99 8.4 5.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein BBS2_C PF14782.1 CDJ62729.1 - 9.9 4.5 10.8 1.1 7.7 3.3 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal BatA PF07584.6 CDJ62730.1 - 0.36 11.0 0.2 0.36 11.0 0.1 2.7 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal ASF1_hist_chap PF04729.8 CDJ62731.1 - 1.4e-24 86.4 0.9 6.3e-14 51.8 0.0 2.2 1 1 1 2 2 2 2 ASF1 like histone chaperone Spc7_N PF15402.1 CDJ62731.1 - 0.98 7.3 20.2 1.2 7.0 14.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF605 PF04652.11 CDJ62731.1 - 2.3 7.5 21.2 2.9 7.1 14.7 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 CDJ62731.1 - 4 5.5 19.6 5.1 5.2 13.6 1.0 1 0 0 1 1 1 0 Transmembrane protein FAM176 PF14851.1 CDJ62731.1 - 5.1 6.7 5.5 5.6 6.6 3.3 1.5 1 1 0 1 1 1 0 FAM176 family TFIIA PF03153.8 CDJ62731.1 - 9.4 6.0 13.5 16 5.2 9.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit rve PF00665.21 CDJ62732.1 - 9.8e-09 35.3 0.0 1.2e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain ATP-synt_ab PF00006.20 CDJ62735.1 - 2.6e-27 95.7 3.3 2e-21 76.5 0.3 4.1 4 0 0 4 4 4 2 ATP synthase alpha/beta family, nucleotide-binding domain RNA_pol_I_A49 PF06870.7 CDJ62737.1 - 0.041 12.4 0.0 0.3 9.6 0.1 1.9 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor Activator_LAG-3 PF11498.3 CDJ62737.1 - 1.8 7.2 12.3 2.5 6.7 8.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SGT1 PF07093.6 CDJ62738.1 - 0.0014 17.0 7.9 0.0014 17.0 5.4 5.4 2 1 2 5 5 5 1 SGT1 protein ISN1 PF06437.6 CDJ62739.1 - 5.3e-76 255.9 0.0 5.6e-50 170.2 0.0 2.2 2 0 0 2 2 2 2 IMP-specific 5'-nucleotidase Hydrolase_3 PF08282.7 CDJ62739.1 - 0.078 12.5 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase adh_short PF00106.20 CDJ62741.1 - 3.8e-09 36.6 13.0 3.8e-09 36.6 9.0 6.1 5 2 1 6 6 6 1 short chain dehydrogenase EB1_binding PF05937.6 CDJ62741.1 - 1.1 9.6 7.6 5.8 7.2 0.7 2.6 2 0 0 2 2 2 0 EB-1 Binding Domain Spt20 PF12090.3 CDJ62741.1 - 7 5.9 24.5 1.2 8.4 1.6 4.5 5 0 0 5 5 5 0 Spt20 family Peptidase_A21 PF03566.8 CDJ62742.1 - 0.11 10.6 8.6 0.14 10.1 6.0 1.1 1 0 0 1 1 1 0 Peptidase family A21 Herpes_UL21 PF03252.8 CDJ62742.1 - 0.37 9.1 3.9 0.44 8.9 2.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL21 DUF342 PF03961.8 CDJ62742.1 - 0.85 7.9 3.6 0.96 7.7 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Rpp20 PF12328.3 CDJ62742.1 - 2.2 7.9 7.1 1.5 8.4 3.6 1.6 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P FAST_2 PF08368.7 CDJ62742.1 - 4.5 7.7 6.9 1 9.8 2.1 1.8 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 TFIIA PF03153.8 CDJ62742.1 - 5 6.9 12.8 5.7 6.7 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 CDJ62743.1 - 0.0061 16.0 1.2 0.0061 16.0 0.9 5.8 4 2 2 6 6 6 2 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDJ62743.1 - 0.026 14.9 8.5 0.026 14.9 5.9 6.5 6 1 0 6 6 6 0 60s Acidic ribosomal protein CPSF100_C PF13299.1 CDJ62745.1 - 0.3 11.2 8.2 0.49 10.5 5.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2839 PF10999.3 CDJ62745.1 - 2.2 8.3 4.1 0.4 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Folate_carrier PF01770.13 CDJ62745.1 - 2.5 6.5 3.6 3.5 6.0 2.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier EcsC PF12787.2 CDJ62746.1 - 0.057 12.8 2.0 0.071 12.4 1.4 1.1 1 0 0 1 1 1 0 EcsC protein family FCP1_C PF09309.5 CDJ62746.1 - 0.6 9.3 5.9 0.64 9.2 4.1 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Suf PF05843.9 CDJ62746.1 - 3.9 7.1 6.2 3.5 7.2 4.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TraV PF09676.5 CDJ62746.1 - 6.5 7.4 8.9 7.2 7.3 6.2 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Fumble PF03630.9 CDJ62747.1 - 6.1 5.5 6.8 14 4.4 4.7 1.5 1 0 0 1 1 1 0 Fumble DASH_Dad3 PF08656.5 CDJ62749.1 - 0.15 11.7 0.1 0.52 10.0 0.0 1.9 1 1 0 1 1 1 0 DASH complex subunit Dad3 HflK_N PF12221.3 CDJ62749.1 - 0.16 11.7 0.7 0.38 10.5 0.3 1.8 1 1 0 1 1 1 0 Bacterial membrane protein N terminal RsbU_N PF08673.5 CDJ62751.1 - 0.017 15.1 34.2 0.19 11.7 1.9 6.4 1 1 6 7 7 7 0 Phosphoserine phosphatase RsbU, N-terminal domain Flg_hook PF02120.11 CDJ62751.1 - 0.48 10.1 28.1 4 7.1 0.3 6.6 2 1 6 8 8 8 0 Flagellar hook-length control protein FliK GDPD PF03009.12 CDJ62751.1 - 1.7 8.1 6.1 39 3.6 2.5 3.1 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family DUF4109 PF13397.1 CDJ62751.1 - 5.2 7.5 35.9 21 5.5 0.5 8.0 2 1 8 10 10 10 0 Domain of unknown function (DUF4109) DLIC PF05783.6 CDJ62752.1 - 3.7 6.1 6.9 0.27 9.8 0.2 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Transketolase_C PF02780.15 CDJ62755.1 - 3.8e-37 126.9 0.1 4.5e-37 126.7 0.1 1.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain zf-met PF12874.2 CDJ62756.1 - 3e-05 24.0 0.4 3e-05 24.0 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDJ62756.1 - 0.0028 17.7 2.0 0.0028 17.7 1.4 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Macoilin PF09726.4 CDJ62756.1 - 0.11 10.7 12.6 0.19 9.9 8.7 1.3 1 0 0 1 1 1 0 Transmembrane protein AKAP95 PF04988.7 CDJ62756.1 - 1.1 9.0 4.7 0.37 10.5 1.4 1.6 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Herpes_UL87 PF03043.9 CDJ62758.1 - 0.0099 14.3 11.6 0.0048 15.3 3.2 2.2 2 0 0 2 2 2 2 Herpesvirus UL87 family Med15 PF09606.5 CDJ62758.1 - 0.061 11.5 119.7 0.019 13.2 15.4 3.4 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4343 PF14243.1 CDJ62758.1 - 0.12 12.2 0.0 0.4 10.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Spore_coat_CotO PF14153.1 CDJ62758.1 - 6.1 6.2 45.2 0.039 13.3 10.1 3.2 3 0 0 3 3 3 0 Spore coat protein CotO TFIIA PF03153.8 CDJ62758.1 - 7.7 6.2 81.8 2.9 7.7 18.7 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit M-inducer_phosp PF06617.8 CDJ62759.1 - 0.061 12.3 9.1 0.17 10.9 0.0 2.8 2 1 1 3 3 3 0 M-phase inducer phosphatase Metallophos PF00149.23 CDJ62761.1 - 3.3e-05 23.3 0.0 8.2e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Baculo_44 PF04631.7 CDJ62761.1 - 0.44 9.0 0.1 1.3 7.6 0.0 1.7 2 0 0 2 2 2 0 Baculovirus hypothetical protein RskA PF10099.4 CDJ62762.1 - 0.31 10.7 10.1 0.4 10.3 7.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.8 CDJ62762.1 - 9.4 6.0 9.7 10 5.8 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPR_2 PF13041.1 CDJ62763.1 - 9.2e-51 169.6 0.0 6.1e-10 38.9 0.0 8.3 4 3 5 9 9 9 7 PPR repeat family PPR_3 PF13812.1 CDJ62763.1 - 9.2e-40 131.5 9.1 3.1e-06 27.0 0.0 11.7 11 0 0 11 11 11 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 CDJ62763.1 - 3.1e-30 103.3 0.4 0.00079 18.8 0.0 9.5 9 1 0 9 9 9 7 PPR repeat PPR PF01535.15 CDJ62763.1 - 2e-29 99.4 5.4 6.8e-05 22.5 0.0 10.1 11 0 0 11 11 11 5 PPR repeat HCNGP PF07818.8 CDJ62764.1 - 2.9e-07 30.4 0.0 4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 HCNGP-like protein DUF4557 PF15101.1 CDJ62765.1 - 0.0092 15.8 24.1 0.0094 15.8 16.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Ribosomal_L37 PF08561.5 CDJ62765.1 - 0.021 14.4 3.8 0.029 13.9 2.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 eIF3_subunit PF08597.5 CDJ62765.1 - 0.029 13.9 10.9 0.029 13.9 7.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4249 PF14054.1 CDJ62765.1 - 0.032 13.6 4.3 0.038 13.3 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) FLO_LFY PF01698.11 CDJ62765.1 - 0.072 11.9 10.5 0.071 11.9 7.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein FNIP_N PF14636.1 CDJ62765.1 - 0.085 13.3 13.0 0.097 13.1 9.0 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus EIIBC-GUT_N PF03612.9 CDJ62765.1 - 0.095 12.3 9.7 0.1 12.1 6.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CRF1 PF10380.4 CDJ62765.1 - 0.096 13.0 5.9 0.1 12.9 4.1 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 eIF-3_zeta PF05091.7 CDJ62765.1 - 0.1 11.2 19.0 0.11 11.1 13.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARP1 PF12569.3 CDJ62765.1 - 0.13 11.0 12.5 0.13 10.9 8.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Serinc PF03348.10 CDJ62765.1 - 0.14 10.8 12.2 0.14 10.8 8.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.4 CDJ62765.1 - 0.2 9.8 39.5 0.19 9.9 27.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FYDLN_acid PF09538.5 CDJ62765.1 - 0.21 12.2 5.0 0.23 12.0 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Utp21 PF04192.7 CDJ62765.1 - 0.24 10.4 14.5 0.29 10.2 10.1 1.1 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Gti1_Pac2 PF09729.4 CDJ62765.1 - 0.24 11.2 9.5 0.27 11.0 6.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TFIIA PF03153.8 CDJ62765.1 - 0.25 11.1 27.8 0.25 11.2 19.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 CDJ62765.1 - 0.29 11.0 14.1 0.3 10.9 9.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cellulose_synt PF03552.9 CDJ62765.1 - 0.29 9.3 4.3 0.28 9.4 2.9 1.0 1 0 0 1 1 1 0 Cellulose synthase FAM176 PF14851.1 CDJ62765.1 - 0.31 10.6 6.2 0.38 10.4 4.3 1.3 1 0 0 1 1 1 0 FAM176 family DUF1764 PF08576.5 CDJ62765.1 - 0.35 11.6 17.4 0.45 11.3 12.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2126 PF09899.4 CDJ62765.1 - 0.35 8.8 9.8 0.35 8.8 6.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) AUX_IAA PF02309.11 CDJ62765.1 - 0.36 10.5 12.3 0.38 10.4 8.5 1.0 1 0 0 1 1 1 0 AUX/IAA family DUF4045 PF13254.1 CDJ62765.1 - 0.4 9.8 10.9 0.4 9.9 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dala_Dala_lig_N PF01820.16 CDJ62765.1 - 0.45 10.8 8.6 0.55 10.5 5.9 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Med15 PF09606.5 CDJ62765.1 - 0.48 8.5 54.4 0.51 8.4 37.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1448 PF07289.6 CDJ62765.1 - 0.51 9.2 9.7 0.46 9.3 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) CPSF100_C PF13299.1 CDJ62765.1 - 0.52 10.4 11.6 0.57 10.3 8.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal UPF0560 PF10577.4 CDJ62765.1 - 0.52 8.4 22.8 0.52 8.5 15.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DDHD PF02862.12 CDJ62765.1 - 0.53 10.0 13.7 0.61 9.8 9.5 1.1 1 0 0 1 1 1 0 DDHD domain Herpes_DNAp_acc PF04929.7 CDJ62765.1 - 0.61 8.9 10.1 0.62 8.9 7.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Baculo_PP31 PF05311.6 CDJ62765.1 - 0.65 9.2 15.9 0.74 9.0 11.0 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF913 PF06025.7 CDJ62765.1 - 0.68 8.6 7.3 0.68 8.6 5.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.1 CDJ62765.1 - 0.74 9.2 23.5 0.86 9.0 16.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Dynamin_N PF00350.18 CDJ62765.1 - 0.81 9.4 8.1 0.81 9.4 5.6 1.1 1 0 0 1 1 1 0 Dynamin family Peptidase_S49_N PF08496.5 CDJ62765.1 - 0.82 9.4 14.2 0.97 9.2 9.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pal1 PF08316.6 CDJ62765.1 - 0.82 10.1 7.9 0.95 9.9 5.5 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein PH_4 PF15404.1 CDJ62765.1 - 0.84 9.1 12.6 1 8.8 8.7 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain OATP PF03137.15 CDJ62765.1 - 0.91 7.4 12.7 0.95 7.4 8.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AIF_C PF14721.1 CDJ62765.1 - 0.96 9.6 15.0 1.2 9.4 10.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BORG_CEP PF14957.1 CDJ62765.1 - 1 10.3 7.9 1.1 10.2 5.4 1.1 1 0 0 1 1 1 0 Cdc42 effector FAM60A PF15396.1 CDJ62765.1 - 1 9.0 10.6 1.2 8.8 7.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SAGA-Tad1 PF12767.2 CDJ62765.1 - 1.1 8.9 17.4 1.1 8.8 12.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Methyltransf_23 PF13489.1 CDJ62765.1 - 1.1 8.9 6.8 9.9 5.8 4.7 2.0 1 1 0 1 1 1 0 Methyltransferase domain Gastrin PF00918.12 CDJ62765.1 - 1.1 10.1 18.6 1.5 9.6 12.9 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF2072 PF09845.4 CDJ62765.1 - 1.2 9.0 9.8 1.6 8.6 6.8 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) GOLD_2 PF13897.1 CDJ62765.1 - 1.3 9.2 8.3 1.6 8.9 5.8 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Tim54 PF11711.3 CDJ62765.1 - 1.3 7.4 11.1 1.4 7.3 7.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.8 CDJ62765.1 - 1.4 8.4 16.6 1.5 8.2 11.5 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paf1 PF03985.8 CDJ62765.1 - 1.4 7.5 20.2 1.6 7.3 14.0 1.0 1 0 0 1 1 1 0 Paf1 DUF2201_N PF13203.1 CDJ62765.1 - 1.4 8.0 15.5 1.5 7.9 10.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF853 PF05872.7 CDJ62765.1 - 1.5 7.1 13.8 1.6 7.0 9.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) YABBY PF04690.8 CDJ62765.1 - 1.5 9.0 9.1 1.5 9.0 6.3 1.1 1 0 0 1 1 1 0 YABBY protein Plasmodium_Vir PF05795.6 CDJ62765.1 - 1.6 7.8 6.1 1.6 7.8 4.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MDFI PF15316.1 CDJ62765.1 - 1.6 8.6 7.4 1.8 8.5 5.1 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Afi1 PF07792.7 CDJ62765.1 - 1.8 8.5 16.8 2.2 8.3 11.6 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4011 PF13195.1 CDJ62765.1 - 1.8 8.5 9.4 2 8.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) PIH1 PF08190.7 CDJ62765.1 - 2.2 7.6 20.7 2.4 7.5 14.4 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 SprA-related PF12118.3 CDJ62765.1 - 2.3 7.4 41.5 2.6 7.3 28.7 1.0 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.8 CDJ62765.1 - 2.4 8.2 26.7 2.9 7.9 18.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1800 PF08811.6 CDJ62765.1 - 2.4 6.9 18.8 2.5 6.9 13.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) AAA_23 PF13476.1 CDJ62765.1 - 2.5 8.3 24.7 2.8 8.2 17.1 1.1 1 0 0 1 1 1 0 AAA domain HemX PF04375.9 CDJ62765.1 - 2.5 6.5 28.0 2.6 6.5 19.4 1.0 1 0 0 1 1 1 0 HemX Kei1 PF08552.6 CDJ62765.1 - 2.6 7.6 14.0 3.2 7.3 9.7 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Neur_chan_memb PF02932.11 CDJ62765.1 - 2.9 7.7 9.6 3.4 7.5 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3306 PF11748.3 CDJ62765.1 - 3.1 8.4 16.9 3.9 8.1 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Hom_end_hint PF05203.11 CDJ62765.1 - 3.1 7.4 10.4 3.5 7.3 7.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint FHIPEP PF00771.15 CDJ62765.1 - 3.3 5.9 11.5 4 5.6 8.0 1.1 1 0 0 1 1 1 0 FHIPEP family Membralin PF09746.4 CDJ62765.1 - 3.3 6.6 5.2 3.1 6.7 3.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF3381 PF11861.3 CDJ62765.1 - 3.4 7.1 17.0 3.9 6.9 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3408 PF11888.3 CDJ62765.1 - 3.7 7.4 14.7 4.5 7.1 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DOR PF14839.1 CDJ62765.1 - 3.8 7.2 19.2 4.3 7.0 13.3 1.1 1 0 0 1 1 1 0 DOR family DUF4512 PF14975.1 CDJ62765.1 - 3.9 8.3 10.0 5.3 7.9 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) SpoIIP PF07454.6 CDJ62765.1 - 4.5 6.3 14.3 5.2 6.1 9.9 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tmp39 PF10271.4 CDJ62765.1 - 4.7 5.7 8.4 5.5 5.5 5.8 1.0 1 0 0 1 1 1 0 Putative transmembrane protein Ycf1 PF05758.7 CDJ62765.1 - 5 4.7 17.4 5.3 4.6 12.1 1.0 1 0 0 1 1 1 0 Ycf1 Presenilin PF01080.12 CDJ62765.1 - 5 5.8 9.2 4.8 5.9 6.4 1.0 1 0 0 1 1 1 0 Presenilin Bul1_N PF04425.7 CDJ62765.1 - 5.4 5.4 15.0 6.1 5.2 10.4 1.0 1 0 0 1 1 1 0 Bul1 N terminus DUF4220 PF13968.1 CDJ62765.1 - 5.6 5.9 7.0 5.8 5.9 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Zip PF02535.17 CDJ62765.1 - 5.8 5.8 5.7 6.2 5.7 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HD-ZIP_N PF04618.7 CDJ62765.1 - 6.4 7.3 8.4 7.5 7.1 5.8 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus HGTP_anticodon2 PF12745.2 CDJ62765.1 - 6.9 5.7 15.7 8.3 5.4 10.9 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF605 PF04652.11 CDJ62765.1 - 7.3 5.8 25.0 7.2 5.8 17.3 1.0 1 0 0 1 1 1 0 Vta1 like Pap_E4 PF02711.9 CDJ62765.1 - 7.3 7.4 14.7 9.9 7.0 10.2 1.1 1 0 0 1 1 1 0 E4 protein RP-C_C PF11800.3 CDJ62765.1 - 7.5 6.1 14.4 8.1 6.0 10.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Folate_carrier PF01770.13 CDJ62765.1 - 7.9 4.8 13.5 8.5 4.7 9.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier DHHW PF14286.1 CDJ62765.1 - 8.8 5.5 14.2 9.8 5.3 9.8 1.0 1 0 0 1 1 1 0 DHHW protein DUF2828 PF11443.3 CDJ62765.1 - 8.9 4.3 14.1 10 4.1 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1266 PF06889.6 CDJ62765.1 - 8.9 6.0 12.4 10 5.8 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) ATAD4 PF15321.1 CDJ62765.1 - 9 7.3 16.7 15 6.7 11.5 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 FimP PF09766.4 CDJ62765.1 - 9.2 5.2 34.0 13 4.7 23.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein CDC45 PF02724.9 CDJ62765.1 - 9.3 4.1 15.9 11 3.8 11.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF822 PF05687.8 CDJ62765.1 - 9.9 6.5 11.7 12 6.2 8.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Peptidase_C1 PF00112.18 CDJ62766.1 - 6.5e-34 117.7 15.4 5.4e-14 52.6 0.5 4.8 3 1 1 4 4 4 3 Papain family cysteine protease CathepsinC_exc PF08773.6 CDJ62766.1 - 0.00036 20.6 1.2 0.074 13.2 0.0 3.2 3 0 0 3 3 3 1 Cathepsin C exclusion domain Propeptide_C1 PF08127.8 CDJ62766.1 - 0.092 12.3 0.9 0.18 11.4 0.6 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide PAT1 PF09770.4 CDJ62766.1 - 1.2 7.3 54.1 0.031 12.5 33.3 1.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HEV_ORF1 PF02444.11 CDJ62767.1 - 7.1 6.8 9.2 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) Ycf1 PF05758.7 CDJ62769.1 - 3 5.4 11.3 5.2 4.6 7.8 1.3 1 0 0 1 1 1 0 Ycf1 ODV-E18 PF10717.4 CDJ62772.1 - 0.09 12.2 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EB PF01683.13 CDJ62772.1 - 0.85 9.7 43.9 1.7 8.7 2.5 9.2 7 4 0 7 7 7 0 EB module Antistasin PF02822.9 CDJ62772.1 - 0.97 9.8 21.4 11 6.4 0.2 8.0 8 0 0 8 8 8 0 Antistasin family DUF4557 PF15101.1 CDJ62773.1 - 0.018 14.8 2.9 0.019 14.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2126 PF09899.4 CDJ62773.1 - 0.031 12.3 1.0 0.034 12.2 0.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4095 PF13338.1 CDJ62773.1 - 0.037 14.1 0.3 0.044 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) R_equi_Vir PF05526.6 CDJ62773.1 - 0.21 11.2 2.1 0.28 10.8 1.5 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RAB3GAP2_N PF14655.1 CDJ62773.1 - 0.23 10.3 5.6 0.32 9.9 3.9 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ProSAAS PF07259.7 CDJ62773.1 - 4.5 6.7 9.0 1.2 8.6 4.0 1.7 1 1 1 2 2 2 0 ProSAAS precursor TauE PF01925.14 CDJ62774.1 - 0.31 10.4 5.9 0.4 10.0 0.4 2.1 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DUF1180 PF06679.7 CDJ62774.1 - 3.6 7.4 12.7 0.047 13.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Spc97_Spc98 PF04130.8 CDJ62775.1 - 7.2e-35 120.3 0.0 1.8e-16 59.5 0.0 2.9 3 0 0 3 3 3 2 Spc97 / Spc98 family SART-1 PF03343.8 CDJ62777.1 - 0.00022 19.7 26.3 0.00022 19.7 18.2 1.4 1 1 0 1 1 1 1 SART-1 family PAT1 PF09770.4 CDJ62777.1 - 0.31 9.2 79.5 0.33 9.1 55.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AvrE PF11725.3 CDJ62777.1 - 0.84 6.5 36.0 0.87 6.5 25.0 1.1 1 0 0 1 1 1 0 Pathogenicity factor Shadoo PF14999.1 CDJ62777.1 - 3.1 7.6 13.3 5.2 6.9 9.2 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Peptidase_M41 PF01434.13 CDJ62778.1 - 5.5e-13 48.8 0.0 8.4e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CDJ62778.1 - 2.8e-06 27.5 0.1 7.7e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDJ62778.1 - 3.3e-05 23.9 0.1 0.00015 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CDJ62778.1 - 3.8e-05 23.3 0.2 0.00013 21.6 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CDJ62778.1 - 0.00012 22.2 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CDJ62778.1 - 0.00042 20.0 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDJ62778.1 - 0.0018 19.0 0.0 0.0034 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDJ62778.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDJ62778.1 - 0.0021 17.1 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 CDJ62778.1 - 0.0038 16.6 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CDJ62778.1 - 0.0044 15.8 0.0 0.0068 15.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CDJ62778.1 - 0.008 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CDJ62778.1 - 0.013 14.7 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CDJ62778.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDJ62778.1 - 0.038 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CDJ62778.1 - 0.056 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 CDJ62778.1 - 0.059 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 CDJ62778.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2638 PF10937.3 CDJ62778.1 - 0.55 11.2 9.5 0.99 10.4 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) Macoilin PF09726.4 CDJ62778.1 - 4.4 5.4 14.3 5.6 5.1 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Mannitol_dh_C PF08125.8 CDJ62779.1 - 1.3e-36 126.0 1.8 1.5e-36 125.8 0.0 1.8 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain UPF0233 PF06781.7 CDJ62779.1 - 0.025 14.1 0.2 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Herpes_U34 PF04541.8 CDJ62779.1 - 0.082 11.8 2.3 0.13 11.1 1.6 1.2 1 0 0 1 1 1 0 Herpesvirus virion protein U34 FimP PF09766.4 CDJ62779.1 - 0.097 11.7 6.2 0.13 11.2 4.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Mannitol_dh PF01232.18 CDJ62779.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain FCP1_C PF09309.5 CDJ62779.1 - 1.8 7.8 5.6 2.5 7.3 3.9 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Claudin_2 PF13903.1 CDJ62780.1 - 0.076 12.6 8.3 0.13 11.9 5.7 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SoxE PF06525.6 CDJ62780.1 - 0.35 10.1 7.8 0.07 12.4 2.7 1.7 1 1 1 2 2 2 0 Sulfocyanin (SoxE) DUF572 PF04502.8 CDJ62780.1 - 1.5 7.9 12.6 1.8 7.7 8.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2052 PF09747.4 CDJ62780.1 - 6 6.7 7.5 7.5 6.4 5.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Herpes_DNAp_acc PF04929.7 CDJ62780.1 - 6.9 5.5 11.6 8 5.3 8.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Serinc PF03348.10 CDJ62780.1 - 8.4 4.9 8.2 8.9 4.9 5.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Myc_N PF01056.13 CDJ62780.1 - 9.1 5.3 19.2 11 5.0 13.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF4202 PF13875.1 CDJ62781.1 - 0.025 14.2 0.1 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) rve_3 PF13683.1 CDJ62781.1 - 0.3 10.6 2.2 0.49 9.9 1.5 1.3 1 0 0 1 1 1 0 Integrase core domain Golgin_A5 PF09787.4 CDJ62781.1 - 0.53 8.7 3.2 0.64 8.4 2.2 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Secretin_N_2 PF07655.8 CDJ62781.1 - 0.78 10.1 14.2 1.1 9.6 9.8 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.4 CDJ62781.1 - 1.2 7.3 5.3 1.1 7.4 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein UNC-50 PF05216.8 CDJ62782.1 - 7.5e-14 51.4 0.2 1.3e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 UNC-50 family Med15 PF09606.5 CDJ62782.1 - 0.00016 20.0 74.6 0.00019 19.8 51.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal MIP-T3 PF10243.4 CDJ62782.1 - 0.00065 18.2 29.2 0.00084 17.9 20.2 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 CDJ62782.1 - 0.033 12.7 1.6 0.04 12.4 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1777 PF08648.7 CDJ62782.1 - 0.11 12.2 28.6 0.14 11.8 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF4045 PF13254.1 CDJ62782.1 - 0.29 10.3 25.6 0.41 9.8 17.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CAF-1_p150 PF11600.3 CDJ62782.1 - 0.52 9.6 34.9 0.87 8.9 24.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAGA-Tad1 PF12767.2 CDJ62782.1 - 1.6 8.3 31.4 2.4 7.7 21.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PLRV_ORF5 PF01690.12 CDJ62782.1 - 3.9 6.5 28.3 5.2 6.1 19.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAPS PF04499.10 CDJ62782.1 - 4.3 5.8 21.4 5.2 5.5 14.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 CDJ62782.1 - 9.8 5.4 26.6 15 4.8 18.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cpn60_TCP1 PF00118.19 CDJ62783.1 - 1.5e-130 436.1 7.8 1.1e-68 232.0 0.0 2.6 1 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family DUF313 PF03754.8 CDJ62783.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF313) PAP1 PF08601.5 CDJ62784.1 - 7.7 6.0 13.2 10 5.6 9.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Shadoo PF14999.1 CDJ62785.1 - 0.16 11.8 8.4 0.27 11.0 5.9 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PsbQ PF05757.6 CDJ62785.1 - 0.43 9.9 4.0 0.43 9.9 2.3 1.3 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) SAE2 PF08573.5 CDJ62786.1 - 0.64 10.7 9.8 0.25 12.0 1.9 2.1 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Endonuc_Holl PF10107.4 CDJ62786.1 - 0.98 9.0 16.4 0.031 13.9 5.0 2.0 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase SAPS PF04499.10 CDJ62786.1 - 1.4 7.4 11.7 1.5 7.3 8.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Exonuc_VII_L PF02601.10 CDJ62786.1 - 1.8 7.6 18.2 2.2 7.3 12.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TCP PF03634.8 CDJ62786.1 - 2.3 8.6 21.7 0.44 10.9 7.9 2.1 2 0 0 2 2 2 0 TCP family transcription factor PBP1_TM PF14812.1 CDJ62786.1 - 2.7 8.3 8.8 0.31 11.3 1.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 CDJ62786.1 - 2.9 7.5 12.0 0.19 11.4 1.4 2.0 2 0 0 2 2 2 0 FAM176 family Zip PF02535.17 CDJ62786.1 - 3.4 6.5 4.6 4.1 6.3 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter OmpH PF03938.9 CDJ62786.1 - 3.6 7.4 38.1 0.22 11.4 14.3 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4557 PF15101.1 CDJ62786.1 - 6.3 6.5 32.0 0.55 10.0 12.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Neur_chan_memb PF02932.11 CDJ62786.1 - 8.2 6.2 11.0 11 5.8 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PP2C PF00481.16 CDJ62787.1 - 2.2e-08 33.8 1.6 2.8e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Glyco_hydro_42 PF02449.10 CDJ62787.1 - 0.061 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Lin-8 PF03353.10 CDJ62787.1 - 0.44 9.7 8.7 0.7 9.1 6.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DNA_pol_viral_N PF00242.12 CDJ62787.1 - 0.45 9.5 7.2 0.59 9.1 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SR-25 PF10500.4 CDJ62787.1 - 0.51 9.7 19.6 0.025 14.0 8.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.7 CDJ62787.1 - 0.99 7.6 5.1 1.5 6.9 3.5 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3807 PF12720.2 CDJ62787.1 - 3.8 7.6 13.1 2.7 8.0 4.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Med15 PF09606.5 CDJ62788.1 - 0.00079 17.7 18.3 0.00079 17.7 12.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal ORC6 PF05460.8 CDJ62788.1 - 0.0065 15.6 3.1 0.0072 15.4 2.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) PAT1 PF09770.4 CDJ62788.1 - 0.008 14.4 14.5 0.0079 14.5 10.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDJ62788.1 - 0.13 12.3 10.8 0.16 12.0 7.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FLO_LFY PF01698.11 CDJ62788.1 - 0.62 8.8 4.3 0.72 8.6 3.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4175 PF13779.1 CDJ62788.1 - 0.64 7.6 23.0 0.66 7.6 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spc7_N PF15402.1 CDJ62788.1 - 1.7 6.5 11.0 2.2 6.2 7.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Baculo_PP31 PF05311.6 CDJ62788.1 - 1.7 7.8 8.5 2 7.5 5.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) ERF PF04404.7 CDJ62788.1 - 1.9 8.0 12.6 3 7.3 8.8 1.3 1 0 0 1 1 1 0 ERF superfamily Ndc1_Nup PF09531.5 CDJ62788.1 - 2.1 6.6 5.2 2.1 6.6 3.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.7 CDJ62788.1 - 2.3 6.7 9.5 2.3 6.7 6.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AIF_C PF14721.1 CDJ62788.1 - 3.9 7.7 5.6 5.1 7.3 3.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF853 PF05872.7 CDJ62788.1 - 4.2 5.5 6.6 5.1 5.3 4.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) HemX PF04375.9 CDJ62788.1 - 4.7 5.6 17.2 5.7 5.4 11.9 1.0 1 0 0 1 1 1 0 HemX DUF4407 PF14362.1 CDJ62788.1 - 5.4 5.8 7.7 6.1 5.7 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.9 CDJ62788.1 - 5.8 4.8 8.7 6.9 4.5 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein FimP PF09766.4 CDJ62788.1 - 6 5.8 14.8 7.3 5.5 10.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein DDHD PF02862.12 CDJ62788.1 - 6.2 6.5 7.8 7.5 6.2 5.4 1.1 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDJ62788.1 - 7.2 5.2 6.3 8.5 4.9 4.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) LSM PF01423.17 CDJ62789.1 - 2.6e-14 52.4 0.0 5.5e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 LSM domain Suf PF05843.9 CDJ62789.1 - 0.00091 19.0 6.4 0.00091 19.0 4.4 2.4 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) HDA2-3 PF11496.3 CDJ62789.1 - 0.0059 15.4 0.5 0.0059 15.4 0.3 1.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 RIC3 PF15361.1 CDJ62789.1 - 0.024 14.8 5.3 0.024 14.8 3.7 2.4 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 SPX PF03105.14 CDJ62789.1 - 0.029 14.1 4.5 0.056 13.2 3.1 1.5 1 1 0 1 1 1 0 SPX domain SM-ATX PF14438.1 CDJ62789.1 - 0.049 13.5 0.7 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Ataxin 2 SM domain LMBR1 PF04791.11 CDJ62789.1 - 0.1 11.1 0.3 0.17 10.4 0.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 CDJ62789.1 - 0.21 11.4 3.3 0.29 10.9 2.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.15 CDJ62789.1 - 0.37 8.7 5.8 0.096 10.7 0.8 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MSA-2c PF12238.3 CDJ62789.1 - 1.6 8.3 6.1 0.13 11.9 0.5 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c FLO_LFY PF01698.11 CDJ62790.1 - 0.00025 20.0 15.4 0.00025 20.0 10.7 2.1 2 0 0 2 2 2 1 Floricaula / Leafy protein ELMO_CED12 PF04727.8 CDJ62791.1 - 2.3e-28 98.8 1.3 9e-28 96.9 0.9 2.1 1 0 0 1 1 1 1 ELMO/CED-12 family FLO_LFY PF01698.11 CDJ62792.1 - 1.9 7.2 7.8 10 4.8 3.7 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Suf PF05843.9 CDJ62792.1 - 2.9 7.5 9.3 2.1 7.9 0.6 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CDJ62793.1 - 0.00092 18.9 11.5 0.9 9.6 1.8 4.5 3 0 0 3 3 3 3 Tetratricopeptide repeat SR-25 PF10500.4 CDJ62793.1 - 0.0019 17.7 8.4 0.0019 17.7 5.8 8.1 8 1 1 9 9 9 2 Nuclear RNA-splicing-associated protein NPL4 PF05021.10 CDJ62794.1 - 1e-05 24.8 0.0 1e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 NPL4 family DUF4452 PF14618.1 CDJ62794.1 - 0.033 14.0 0.5 0.036 13.8 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) DUF1645 PF07816.6 CDJ62794.1 - 1.4 9.3 5.7 1.7 9.0 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) AAA_23 PF13476.1 CDJ62795.1 - 0.16 12.3 21.3 0.2 11.9 14.7 1.2 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 CDJ62795.1 - 0.39 10.0 43.3 0.45 9.8 30.0 1.0 1 0 0 1 1 1 0 Vta1 like Med15 PF09606.5 CDJ62795.1 - 1.4 7.0 71.8 1.8 6.6 49.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HCO3_cotransp PF00955.16 CDJ62795.1 - 1.9 7.0 4.8 2.3 6.7 3.3 1.3 1 0 0 1 1 1 0 HCO3- transporter family RNA_pol_Rpb1_2 PF00623.15 CDJ62795.1 - 3.8 7.4 9.7 7.3 6.5 6.7 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 CAF-1_p150 PF11600.3 CDJ62795.1 - 6.7 6.0 60.9 0.031 13.6 30.5 2.1 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDJ62795.1 - 7 4.7 58.6 8.6 4.4 40.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2201_N PF13203.1 CDJ62796.1 - 0.0079 15.4 19.6 0.0079 15.4 13.6 2.4 2 1 1 3 3 2 1 Putative metallopeptidase domain Pox_Ag35 PF03286.9 CDJ62796.1 - 0.012 15.1 16.4 0.024 14.1 11.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein LMBR1 PF04791.11 CDJ62796.1 - 0.012 14.1 2.6 0.013 14.1 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HlyD_2 PF12700.2 CDJ62796.1 - 0.024 13.7 12.6 0.034 13.3 8.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein CDC45 PF02724.9 CDJ62796.1 - 0.032 12.2 24.6 0.052 11.5 17.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.6 CDJ62796.1 - 0.08 12.8 30.7 0.12 12.2 21.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Tim54 PF11711.3 CDJ62796.1 - 0.099 11.2 11.8 0.18 10.3 8.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Raftlin PF15250.1 CDJ62796.1 - 0.16 10.4 18.9 0.35 9.3 12.0 1.9 2 0 0 2 2 2 0 Raftlin Zip PF02535.17 CDJ62796.1 - 0.17 10.8 6.7 0.48 9.3 4.7 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 CDJ62796.1 - 0.17 9.5 23.3 0.21 9.2 16.1 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 CDJ62796.1 - 0.19 11.7 25.5 0.35 10.8 17.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.8 CDJ62796.1 - 0.22 10.0 18.7 0.46 8.9 12.9 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.8 CDJ62796.1 - 0.26 10.2 0.7 0.34 9.8 0.5 1.4 1 0 0 1 1 1 0 Otopetrin Nop14 PF04147.7 CDJ62796.1 - 0.43 8.4 30.0 0.61 7.9 20.8 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 CDJ62796.1 - 0.6 7.7 22.7 0.84 7.2 15.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SDA1 PF05285.7 CDJ62796.1 - 0.99 8.6 30.8 0.052 12.8 17.5 1.5 2 0 0 2 2 2 0 SDA1 GAGA_bind PF06217.7 CDJ62796.1 - 1.4 8.8 17.1 2.1 8.2 11.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CDJ62796.1 - 1.5 8.6 26.4 4.4 7.1 18.3 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2146 PF10220.4 CDJ62796.1 - 1.6 6.5 19.2 2.3 6.0 13.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) eIF3_subunit PF08597.5 CDJ62796.1 - 2 7.9 28.5 4.1 6.8 19.7 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4220 PF13968.1 CDJ62796.1 - 2.4 7.1 11.5 4 6.4 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF1510 PF07423.6 CDJ62796.1 - 4.6 6.5 38.7 8.6 5.6 26.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_env PF01673.13 CDJ62796.1 - 5.2 5.5 11.4 8.9 4.7 7.9 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein TFIIA PF03153.8 CDJ62796.1 - 5.7 6.7 41.3 11 5.7 23.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 CDJ62797.1 - 0.05 11.6 13.9 0.053 11.5 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF6 PF04935.7 CDJ62797.1 - 0.16 11.2 12.8 0.19 10.9 8.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 SLD3 PF08639.5 CDJ62797.1 - 0.21 10.1 31.7 0.23 10.0 21.9 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Nop25 PF09805.4 CDJ62797.1 - 0.26 11.3 7.6 0.36 10.8 5.3 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Mem_trans PF03547.13 CDJ62797.1 - 0.28 9.4 11.0 0.31 9.2 7.6 1.2 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 CDJ62797.1 - 0.29 9.7 12.7 0.32 9.5 8.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Herpes_env PF01673.13 CDJ62797.1 - 0.96 7.9 15.4 1.3 7.4 10.7 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF572 PF04502.8 CDJ62797.1 - 1.4 8.0 26.6 1.7 7.8 18.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DivIC PF04977.10 CDJ62797.1 - 4.3 6.8 9.1 7.4 6.1 6.3 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF2217 PF10265.4 CDJ62797.1 - 5 5.7 23.2 6.7 5.3 16.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PLRV_ORF5 PF01690.12 CDJ62797.1 - 5.1 6.1 19.8 6 5.8 13.7 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4647 PF15504.1 CDJ62797.1 - 6 5.6 18.8 6.9 5.4 13.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Hid1 PF12722.2 CDJ62797.1 - 8.3 3.9 25.3 9.7 3.7 17.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 CDJ62797.1 - 9.5 4.3 35.4 12 4.0 24.5 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF3253 PF11625.3 CDJ62798.1 - 0.0058 16.4 0.1 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) CBS PF00571.23 CDJ62798.1 - 0.047 13.4 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 CBS domain SAPS PF04499.10 CDJ62798.1 - 7.6 5.0 7.9 0.3 9.6 1.0 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Pkinase PF00069.20 CDJ62799.1 - 8.4e-42 143.1 0.0 6.2e-14 51.7 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ62799.1 - 2.5e-21 75.9 0.0 1.9e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.27 CDJ62799.1 - 5.1e-06 25.4 0.0 0.02 14.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CDJ62799.1 - 4.7e-05 23.4 0.0 0.15 12.2 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CDJ62799.1 - 0.00031 20.3 0.2 1 9.4 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CDJ62799.1 - 0.0079 15.7 0.2 0.78 9.3 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 CDJ62799.1 - 0.069 12.5 0.2 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 EF hand HIT PF01230.18 CDJ62800.1 - 2.2e-22 79.4 0.1 2.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CDJ62800.1 - 1.4e-10 41.3 0.0 1.7e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.24 CDJ62801.1 - 6.2e-94 311.1 0.0 1.4e-46 157.9 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CDJ62801.1 - 5.3e-23 80.7 0.6 1.2e-22 79.6 0.4 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CDJ62801.1 - 3.7e-13 49.0 0.0 6.5e-06 25.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CDJ62801.1 - 1.9e-12 47.4 0.1 5.1e-05 23.4 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 CDJ62801.1 - 1.9e-12 48.0 0.0 1e-05 26.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CDJ62801.1 - 2.8e-12 47.0 0.1 0.00014 21.9 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 CDJ62801.1 - 1.8e-11 44.0 0.0 1.5e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CDJ62801.1 - 2.2e-11 43.9 0.0 1.9e-06 27.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CDJ62801.1 - 1.2e-10 41.2 0.1 1.8e-05 24.4 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.12 CDJ62801.1 - 7.5e-10 38.3 0.0 1.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 CDJ62801.1 - 2.7e-09 36.9 0.0 0.00027 20.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CDJ62801.1 - 1.5e-08 33.8 0.0 0.00057 18.7 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 CDJ62801.1 - 2.7e-08 33.4 2.5 0.11 11.9 0.0 3.7 2 2 2 4 4 4 3 AAA domain Zeta_toxin PF06414.7 CDJ62801.1 - 6.5e-08 31.9 0.0 0.0045 16.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 CDJ62801.1 - 2.2e-07 31.2 0.0 0.021 15.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 CDJ62801.1 - 5e-07 29.3 1.6 0.017 14.8 0.4 3.2 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 CDJ62801.1 - 5.5e-07 28.9 0.3 0.032 13.3 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CDJ62801.1 - 7e-07 29.3 0.0 0.016 15.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 CDJ62801.1 - 1.5e-06 27.7 0.0 0.048 13.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 CDJ62801.1 - 3.2e-06 27.1 0.0 0.085 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CDJ62801.1 - 3.8e-06 26.6 0.0 0.41 10.2 0.0 3.8 3 1 0 4 4 4 2 NACHT domain Arch_ATPase PF01637.13 CDJ62801.1 - 5e-06 26.3 0.0 0.049 13.3 0.0 3.2 2 2 2 4 4 3 2 Archaeal ATPase Sigma54_activ_2 PF14532.1 CDJ62801.1 - 6.7e-06 26.1 0.0 0.04 13.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 CDJ62801.1 - 2.6e-05 23.9 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 CDJ62801.1 - 3.8e-05 22.9 0.2 2.1 7.4 0.0 3.3 2 1 1 3 3 3 1 KaiC ABC_tran PF00005.22 CDJ62801.1 - 4.4e-05 23.7 0.0 0.24 11.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ResIII PF04851.10 CDJ62801.1 - 7.9e-05 22.5 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 CDJ62801.1 - 0.00011 21.1 0.1 0.29 9.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 CDJ62801.1 - 0.00013 21.5 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Vps4_C PF09336.5 CDJ62801.1 - 0.00013 21.7 0.1 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.12 CDJ62801.1 - 0.00019 20.4 0.0 0.45 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 CDJ62801.1 - 0.00055 19.4 0.0 1.2 8.5 0.0 3.4 2 2 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 CDJ62801.1 - 0.00079 18.4 0.0 0.33 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 CDJ62801.1 - 0.0012 18.6 0.3 2.6 7.7 0.0 3.7 3 0 0 3 3 3 1 NTPase SKI PF01202.17 CDJ62801.1 - 0.0012 18.7 0.1 3.4 7.5 0.0 3.2 3 0 0 3 3 3 0 Shikimate kinase PhoH PF02562.11 CDJ62801.1 - 0.0016 17.7 0.2 1.2 8.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 CDJ62801.1 - 0.0019 17.8 0.0 2.1 7.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 CDJ62801.1 - 0.0036 17.2 0.1 0.49 10.2 0.0 2.7 3 0 0 3 3 2 1 Cytidylate kinase-like family Bac_DnaA PF00308.13 CDJ62801.1 - 0.0058 16.2 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein DUF2075 PF09848.4 CDJ62801.1 - 0.0098 14.9 0.0 1.3 7.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 CDJ62801.1 - 0.013 15.1 0.0 5.6 6.6 0.0 3.0 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CDJ62801.1 - 0.014 14.9 0.0 7.4 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 CDJ62801.1 - 0.021 13.8 0.2 2.4 7.0 0.0 3.2 2 2 2 4 4 4 0 KAP family P-loop domain AAA_10 PF12846.2 CDJ62801.1 - 0.03 13.7 1.0 6.9 6.0 0.0 3.1 2 1 0 3 3 3 0 AAA-like domain AAA_23 PF13476.1 CDJ62801.1 - 0.046 14.0 0.0 7.6 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CDJ62801.1 - 0.051 13.1 0.0 4.9 6.7 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.24 CDJ62801.1 - 0.11 12.0 0.0 22 4.4 0.0 3.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase KTI12 PF08433.5 CDJ62801.1 - 0.12 11.5 0.0 6.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 CDJ62801.1 - 0.13 11.8 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CDJ62801.1 - 0.14 10.7 0.0 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Zot PF05707.7 CDJ62801.1 - 0.15 11.5 0.3 9.1 5.6 0.1 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_21 PF13304.1 CDJ62801.1 - 1.7 8.5 2.6 30 4.4 0.0 3.1 3 1 0 3 3 3 0 AAA domain VTC PF09359.5 CDJ62803.1 - 4.5e-70 235.8 0.0 6.1e-40 137.0 0.0 2.2 1 1 1 2 2 2 2 VTC domain DUF202 PF02656.10 CDJ62803.1 - 0.00026 21.1 0.3 0.00026 21.1 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) HJURP_C PF12347.3 CDJ62804.1 - 0.047 13.2 0.5 0.1 12.2 0.3 1.6 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat TROVE PF05731.6 CDJ62804.1 - 0.056 12.2 1.1 0.077 11.7 0.8 1.1 1 0 0 1 1 1 0 TROVE domain DUF4510 PF14971.1 CDJ62804.1 - 0.056 13.6 1.2 0.14 12.3 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Ribosomal_L6 PF00347.18 CDJ62805.1 - 1.1e-25 89.9 1.0 4.4e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DnaJ PF00226.26 CDJ62806.1 - 1.6e-10 40.5 0.4 2.8e-09 36.5 0.0 2.7 2 0 0 2 2 2 1 DnaJ domain DUF221 PF02714.10 CDJ62807.1 - 1.4e-07 30.7 0.1 1.9e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 E1-N PF14463.1 CDJ62808.1 - 0.53 9.8 7.1 0.028 14.0 0.4 2.2 3 0 0 3 3 3 0 E1 N-terminal domain Mito_carr PF00153.22 CDJ62809.1 - 2.6e-49 164.9 6.1 1.6e-18 66.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb4 PF03874.11 CDJ62811.1 - 2.8e-13 49.9 0.0 3.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2870 PF11069.3 CDJ62813.1 - 1.7e-31 108.1 0.1 4e-31 106.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) ubiquitin PF00240.18 CDJ62813.1 - 0.057 12.8 1.3 14 5.1 0.0 3.3 4 0 0 4 4 4 0 Ubiquitin family INCENP_ARK-bind PF03941.10 CDJ62813.1 - 0.092 12.6 0.1 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region DUF1180 PF06679.7 CDJ62814.1 - 0.16 11.8 0.8 0.26 11.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PGC7_Stella PF15549.1 CDJ62814.1 - 2.2 8.2 6.8 0.55 10.2 2.4 1.6 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain P_C PF06640.6 CDJ62814.1 - 4.6 7.1 9.1 51 3.7 6.2 2.0 1 1 0 1 1 1 0 P protein C-terminus Trypsin_2 PF13365.1 CDJ62816.1 - 9e-10 38.5 0.5 0.00011 22.2 0.0 2.7 1 1 1 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.21 CDJ62816.1 - 3.9e-06 26.6 2.4 0.0054 16.3 0.2 2.6 1 1 0 2 2 2 2 Trypsin PDZ_2 PF13180.1 CDJ62816.1 - 1.1e-05 25.2 0.1 0.00014 21.6 0.0 2.5 2 0 0 2 2 2 1 PDZ domain MMR_HSR1 PF01926.18 CDJ62817.1 - 6.7e-17 61.5 0.1 9e-14 51.4 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.6 CDJ62817.1 - 1.4e-11 44.0 6.8 1.4e-11 44.0 4.7 3.6 3 1 1 4 4 4 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.13 CDJ62817.1 - 6e-09 35.3 0.0 6.2e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CDJ62817.1 - 0.00021 20.7 2.1 0.088 12.2 0.0 4.4 3 3 2 5 5 5 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CDJ62817.1 - 0.0011 18.1 0.0 0.003 16.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDJ62817.1 - 0.039 13.9 0.2 0.039 13.9 0.1 4.1 3 3 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 CDJ62817.1 - 0.13 12.0 0.1 0.35 10.5 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CDJ62817.1 - 0.16 12.5 0.5 0.81 10.1 0.0 2.4 2 1 1 3 3 3 0 Miro-like protein SRPRB PF09439.5 CDJ62817.1 - 0.17 11.1 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CDJ62817.1 - 0.22 11.3 16.0 0.6 9.9 0.1 4.2 3 2 1 4 4 4 0 Dynamin family DUF687 PF05095.7 CDJ62817.1 - 0.44 8.8 2.4 0.71 8.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF687) RRM_6 PF14259.1 CDJ62818.1 - 2.1e-26 91.6 0.0 2.1e-07 30.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ62818.1 - 1.5e-22 78.9 0.0 2.3e-07 30.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ62818.1 - 1.7e-09 37.3 0.0 0.019 14.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDK2AP PF09806.4 CDJ62818.1 - 0.29 11.3 4.1 0.53 10.4 2.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein rve PF00665.21 CDJ62820.1 - 3.9e-17 62.4 0.0 8.6e-17 61.3 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.1 CDJ62820.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PNRC PF15365.1 CDJ62821.1 - 0.42 10.6 0.2 0.42 10.6 0.1 4.6 2 2 1 3 3 3 0 Proline-rich nuclear receptor coactivator Med15 PF09606.5 CDJ62821.1 - 2.2 6.3 73.6 2.6 6.1 51.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal rve PF00665.21 CDJ62822.1 - 4.3e-17 62.3 0.2 1e-16 61.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Herpes_glycop PF01528.11 CDJ62823.1 - 0.0082 14.8 0.1 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus glycoprotein M Methyltransf_26 PF13659.1 CDJ62824.1 - 0.15 12.0 1.6 1.9 8.5 0.5 2.6 1 1 0 1 1 1 0 Methyltransferase domain Thioredoxin_8 PF13905.1 CDJ62825.1 - 1.6e-19 69.7 0.0 2.6e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CDJ62825.1 - 9.4e-08 32.2 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CDJ62825.1 - 0.00022 20.9 0.0 0.0011 18.6 0.0 2.2 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin PF00085.15 CDJ62825.1 - 0.00091 18.8 0.0 0.0092 15.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 CDJ62825.1 - 0.0046 16.9 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 CDJ62825.1 - 0.051 13.1 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Redoxin Kelch_5 PF13854.1 CDJ62826.1 - 6.9e-11 41.8 1.9 1.5e-06 28.0 0.0 5.3 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 CDJ62826.1 - 1e-06 28.4 2.0 0.0037 17.0 0.0 5.1 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_3 PF13415.1 CDJ62826.1 - 5.3e-05 23.2 21.2 0.04 14.0 0.0 8.1 8 1 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CDJ62826.1 - 0.0036 17.4 0.0 0.29 11.3 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Peptidase_A22B PF04258.8 CDJ62827.1 - 3.7e-63 213.7 4.9 5.6e-63 213.1 3.4 1.2 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 CDJ62827.1 - 0.058 12.5 13.4 0.058 12.5 5.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1119) UPF0233 PF06781.7 CDJ62827.1 - 3 7.5 7.9 0.27 10.8 0.2 2.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) MOZ_SAS PF01853.13 CDJ62828.1 - 1.7e-33 115.4 0.0 4.3e-33 114.1 0.0 1.6 1 1 1 2 2 2 1 MOZ/SAS family Tudor-knot PF11717.3 CDJ62828.1 - 5e-11 42.1 0.0 1.4e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Asp_protease_2 PF13650.1 CDJ62829.1 - 4e-08 33.6 0.0 8.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ62829.1 - 1.5e-07 31.1 0.0 9.2e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ62829.1 - 0.00025 20.8 0.0 0.00068 19.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ62829.1 - 0.0016 18.4 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3552 PF12072.3 CDJ62829.1 - 0.027 13.6 0.8 0.04 13.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) rve PF00665.21 CDJ62830.1 - 3.6e-18 65.8 0.0 8.1e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDJ62830.1 - 1.1e-10 41.0 0.0 2.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDJ62830.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) V-ATPase_G PF03179.10 CDJ62832.1 - 0.0011 19.2 8.6 0.0019 18.4 6.0 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ABA_GPCR PF12430.3 CDJ62833.1 - 1.1e-45 155.1 7.2 2e-45 154.3 5.0 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CDJ62833.1 - 9.3e-18 64.0 2.0 1.9e-17 63.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) EMP70 PF02990.11 CDJ62833.1 - 0.018 13.5 1.7 0.037 12.5 1.2 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 WD40 PF00400.27 CDJ62834.1 - 2.1e-33 112.9 13.5 2.7e-10 39.7 0.8 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CDJ62834.1 - 0.0015 18.2 0.1 0.48 10.1 0.0 2.9 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term eIF2A PF08662.6 CDJ62834.1 - 0.014 15.0 0.0 12 5.5 0.0 3.8 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Phasin PF05597.6 CDJ62835.1 - 0.035 13.8 2.0 0.18 11.5 0.1 2.5 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) dCMP_cyt_deam_1 PF00383.17 CDJ62836.1 - 1.4e-21 76.0 4.5 1.4e-21 76.0 3.1 2.1 3 0 0 3 3 3 1 Cytidine and deoxycytidylate deaminase zinc-binding region CoaE PF01121.15 CDJ62836.1 - 0.14 11.5 0.1 0.28 10.5 0.0 1.5 2 0 0 2 2 2 0 Dephospho-CoA kinase Cpn60_TCP1 PF00118.19 CDJ62837.1 - 4.9e-17 61.7 0.1 6.3e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lin0512_fam PF09585.5 CDJ62837.1 - 0.055 13.0 0.4 0.11 12.0 0.2 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) Ribosomal_60s PF00428.14 CDJ62837.1 - 1.6 9.1 7.5 2.9 8.3 5.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein IncA PF04156.9 CDJ62838.1 - 3.8e-07 29.9 5.5 3.8e-07 29.9 3.8 2.9 3 0 0 3 3 2 1 IncA protein Claudin_2 PF13903.1 CDJ62838.1 - 4.5e-05 23.1 13.7 0.0096 15.6 9.5 2.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Spt20 PF12090.3 CDJ62838.1 - 0.0011 18.4 7.9 0.035 13.4 2.0 2.2 2 0 0 2 2 2 2 Spt20 family zf-DHHC PF01529.15 CDJ62838.1 - 0.034 13.5 0.7 0.42 9.9 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase FimP PF09766.4 CDJ62838.1 - 0.06 12.3 20.4 0.014 14.5 4.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein Suf PF05843.9 CDJ62838.1 - 0.11 12.2 19.3 0.24 11.1 5.8 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4207 PF13904.1 CDJ62838.1 - 0.27 10.5 27.8 1.3 8.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) U79_P34 PF03064.11 CDJ62838.1 - 0.34 10.3 9.8 2.3 7.6 0.3 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF2052 PF09747.4 CDJ62838.1 - 0.49 10.3 14.5 2.4 8.0 0.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4557 PF15101.1 CDJ62838.1 - 1.9 8.2 26.1 1 9.1 9.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) EphA2_TM PF14575.1 CDJ62838.1 - 2.7 8.4 8.8 0.26 11.6 0.4 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FLO_LFY PF01698.11 CDJ62838.1 - 2.8 6.6 13.7 4.4 6.0 5.5 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 CDJ62838.1 - 7.1 6.4 12.1 0.96 9.2 2.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Band_3_cyto PF07565.8 CDJ62838.1 - 9.9 5.5 12.3 12 5.2 3.3 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SOBP PF15279.1 CDJ62839.1 - 0.0043 17.4 32.5 0.0061 16.9 22.6 1.3 1 0 0 1 1 1 1 Sine oculis-binding protein CAF-1_p150 PF11600.3 CDJ62839.1 - 0.037 13.3 34.6 0.071 12.4 24.0 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 CDJ62839.1 - 0.33 9.4 1.4 0.39 9.2 1.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Parvo_coat PF00740.13 CDJ62839.1 - 0.74 8.6 20.4 0.98 8.2 14.1 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SAGA-Tad1 PF12767.2 CDJ62839.1 - 1.4 8.5 28.8 2.4 7.7 19.9 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ycf1 PF05758.7 CDJ62839.1 - 1.4 6.5 17.7 1.8 6.2 12.3 1.1 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDJ62839.1 - 2.5 6.5 24.2 3.5 6.1 16.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gti1_Pac2 PF09729.4 CDJ62839.1 - 3.6 7.4 12.3 9.5 6.0 8.5 1.8 1 0 0 1 1 1 0 Gti1/Pac2 family Iso_dh PF00180.15 CDJ62841.1 - 1.7e-36 125.8 0.0 3e-36 125.0 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4259 PF14078.1 CDJ62841.1 - 1.3 9.4 3.9 3.6 8.0 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) DUF2722 PF10846.3 CDJ62842.1 - 0.0018 17.4 21.0 0.28 10.1 0.3 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2722) FimP PF09766.4 CDJ62842.1 - 0.0018 17.4 9.8 0.0018 17.4 6.8 3.1 3 0 0 3 3 3 2 Fms-interacting protein Apt1 PF10351.4 CDJ62842.1 - 0.063 12.1 2.9 0.11 11.3 2.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAGA-Tad1 PF12767.2 CDJ62842.1 - 0.35 10.4 21.6 0.13 11.8 3.4 3.2 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Spt20 PF12090.3 CDJ62842.1 - 0.53 9.6 29.2 0.3 10.4 4.7 3.3 3 0 0 3 3 3 0 Spt20 family Ctr PF04145.10 CDJ62842.1 - 1.8 8.5 11.5 3 7.8 1.2 3.5 3 0 0 3 3 3 0 Ctr copper transporter family Band_3_cyto PF07565.8 CDJ62842.1 - 3.4 7.1 17.3 1.5 8.2 3.3 3.0 3 0 0 3 3 3 0 Band 3 cytoplasmic domain TauE PF01925.14 CDJ62843.1 - 2.4e-08 33.7 17.1 2.4e-08 33.7 11.9 2.1 2 1 0 2 2 2 1 Sulfite exporter TauE/SafE Daxx PF03344.10 CDJ62843.1 - 1.2 7.5 50.2 1.8 6.9 34.8 1.2 1 0 0 1 1 1 0 Daxx Family Med15 PF09606.5 CDJ62843.1 - 4.8 5.2 109.6 7.2 4.6 76.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PLRV_ORF5 PF01690.12 CDJ62843.1 - 8.6 5.3 35.4 15 4.6 24.6 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Prefoldin PF02996.12 CDJ62845.1 - 2.4e-09 36.8 1.2 2.4e-09 36.8 0.8 3.1 2 2 0 2 2 2 1 Prefoldin subunit Amelogenin PF02948.10 CDJ62845.1 - 0.066 13.8 12.0 0.075 13.6 8.3 1.1 1 0 0 1 1 1 0 Amelogenin FUSC PF04632.7 CDJ62845.1 - 0.25 9.7 3.1 0.26 9.6 2.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rrn6 PF10214.4 CDJ62845.1 - 4.9 5.1 9.7 6.2 4.7 6.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF1510 PF07423.6 CDJ62846.1 - 0.058 12.7 17.6 0.06 12.7 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Folate_carrier PF01770.13 CDJ62846.1 - 0.14 10.6 11.7 0.14 10.6 8.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.15 CDJ62846.1 - 0.16 9.9 13.0 0.16 10.0 9.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ycf1 PF05758.7 CDJ62846.1 - 0.31 8.7 18.6 0.32 8.6 12.9 1.0 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 CDJ62846.1 - 0.92 8.2 16.9 0.91 8.3 11.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2561 PF10812.3 CDJ62846.1 - 0.99 8.9 4.4 1.1 8.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) FYDLN_acid PF09538.5 CDJ62846.1 - 1 9.9 8.7 1.1 9.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) AIF_C PF14721.1 CDJ62846.1 - 1.1 9.4 15.6 1.1 9.4 10.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM176 PF14851.1 CDJ62846.1 - 1.2 8.8 9.4 1.5 8.4 6.5 1.3 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.3 CDJ62846.1 - 1.3 7.5 16.1 1.4 7.4 11.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nucleoside_tran PF01733.13 CDJ62846.1 - 1.6 7.8 9.3 1.8 7.6 6.4 1.0 1 0 0 1 1 1 0 Nucleoside transporter Peptidase_S49_N PF08496.5 CDJ62846.1 - 1.9 8.3 17.6 2 8.1 12.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Dala_Dala_lig_N PF01820.16 CDJ62846.1 - 2 8.7 10.2 2.5 8.4 7.1 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DDHD PF02862.12 CDJ62846.1 - 2.1 8.1 18.2 2.1 8.1 12.6 1.0 1 0 0 1 1 1 0 DDHD domain Baculo_PP31 PF05311.6 CDJ62846.1 - 2.2 7.5 20.0 2.1 7.5 13.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) BcsB PF03170.8 CDJ62846.1 - 2.8 5.8 13.6 2.9 5.7 9.4 1.0 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Ctr PF04145.10 CDJ62846.1 - 3.2 7.7 11.5 3.7 7.6 8.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DDRGK PF09756.4 CDJ62846.1 - 3.3 7.0 29.4 3.5 6.9 20.4 1.0 1 0 0 1 1 1 0 DDRGK domain FPN1 PF06963.7 CDJ62846.1 - 3.3 5.9 8.7 4 5.7 6.0 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) YABBY PF04690.8 CDJ62846.1 - 3.8 7.7 14.1 3.8 7.7 9.8 1.0 1 0 0 1 1 1 0 YABBY protein GAGA_bind PF06217.7 CDJ62846.1 - 4.7 7.1 18.1 4.7 7.0 12.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CPSF100_C PF13299.1 CDJ62846.1 - 4.7 7.3 17.6 4.9 7.3 12.2 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.10 CDJ62846.1 - 4.7 5.8 18.0 4.6 5.8 12.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3260 PF11658.3 CDJ62846.1 - 4.9 5.1 17.7 5.2 5.1 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Mem_trans PF03547.13 CDJ62846.1 - 5 5.3 10.1 4.7 5.3 7.0 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF2370 PF10176.4 CDJ62846.1 - 5 6.4 11.1 4.8 6.4 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF3474 PF11960.3 CDJ62846.1 - 5.2 7.0 5.6 7.3 6.6 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Dynamin_N PF00350.18 CDJ62846.1 - 5.2 6.8 13.3 5.6 6.7 9.2 1.1 1 0 0 1 1 1 0 Dynamin family AUX_IAA PF02309.11 CDJ62846.1 - 5.6 6.6 16.0 5.5 6.6 11.1 1.1 1 0 0 1 1 1 0 AUX/IAA family Peptidase_S15 PF02129.13 CDJ62846.1 - 6.9 5.9 16.4 6.9 6.0 11.3 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peroxin-13_N PF04088.8 CDJ62846.1 - 7.2 6.5 11.1 8.3 6.3 7.7 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4446 PF14584.1 CDJ62846.1 - 8 6.2 11.1 9 6.1 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) RR_TM4-6 PF06459.7 CDJ62846.1 - 8.2 6.2 20.1 8.5 6.1 13.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FHIPEP PF00771.15 CDJ62846.1 - 8.5 4.5 13.2 11 4.2 9.2 1.3 1 0 0 1 1 1 0 FHIPEP family Kei1 PF08552.6 CDJ62846.1 - 9.2 5.8 15.1 9.9 5.7 10.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3633 PF12315.3 CDJ62847.1 - 0.017 14.4 1.7 0.029 13.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Chorion_2 PF03964.10 CDJ62847.1 - 0.25 11.8 19.7 0.089 13.3 2.2 2.3 2 0 0 2 2 2 0 Chorion family 2 BUD22 PF09073.5 CDJ62847.1 - 0.4 9.7 5.2 0.55 9.2 3.6 1.2 1 0 0 1 1 1 0 BUD22 SUZ PF12752.2 CDJ62847.1 - 2.3 8.8 8.8 5.2 7.6 6.1 1.6 1 0 0 1 1 1 0 SUZ domain Phosphoprotein PF00922.12 CDJ62847.1 - 2.3 7.3 8.7 3.1 6.9 6.0 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF3446 PF11928.3 CDJ62847.1 - 9.6 6.4 22.4 4.3 7.6 13.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) IncA PF04156.9 CDJ62848.1 - 0.0024 17.5 7.8 0.0026 17.3 5.4 1.0 1 0 0 1 1 1 1 IncA protein DFP PF04127.10 CDJ62848.1 - 0.03 13.9 5.1 0.034 13.7 3.6 1.1 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF2232 PF09991.4 CDJ62848.1 - 0.31 9.9 1.3 0.37 9.7 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) BCAS3 PF12490.3 CDJ62848.1 - 0.39 9.9 3.4 0.44 9.8 2.3 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 Wzz PF02706.10 CDJ62848.1 - 0.77 9.5 8.4 0.97 9.2 5.8 1.1 1 0 0 1 1 1 0 Chain length determinant protein RFX1_trans_act PF04589.8 CDJ62848.1 - 1.6 8.4 13.9 1.8 8.2 9.6 1.0 1 0 0 1 1 1 0 RFX1 transcription activation region DUF3450 PF11932.3 CDJ62848.1 - 1.9 7.7 15.8 2 7.5 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Gastrin PF00918.12 CDJ62848.1 - 2.3 9.0 9.9 2.7 8.8 6.8 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Adeno_PIX PF03955.9 CDJ62848.1 - 4.2 7.9 8.9 6 7.4 6.2 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) DUF3123 PF11321.3 CDJ62848.1 - 7.8 6.8 8.0 11 6.3 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) R_equi_Vir PF05526.6 CDJ62848.1 - 9.8 5.7 7.0 11 5.5 4.9 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Adenylsucc_synt PF00709.16 CDJ62849.1 - 8.9e-106 354.0 0.0 1.7e-104 349.8 0.0 2.0 1 1 0 1 1 1 1 Adenylosuccinate synthetase SGT1 PF07093.6 CDJ62849.1 - 0.63 8.3 4.3 0.88 7.8 3.0 1.1 1 0 0 1 1 1 0 SGT1 protein DUF4557 PF15101.1 CDJ62849.1 - 0.73 9.6 5.9 1.4 8.7 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CDK2AP PF09806.4 CDJ62849.1 - 2.2 8.4 20.9 1.1 9.3 0.9 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Activator_LAG-3 PF11498.3 CDJ62850.1 - 0.9 8.2 44.0 1.9 7.1 15.7 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SpoVR PF04293.8 CDJ62850.1 - 4.9 5.4 9.2 0.95 7.7 0.5 2.1 2 0 0 2 2 2 0 SpoVR like protein DUF4446 PF14584.1 CDJ62850.1 - 6.7 6.5 8.8 0.55 10.0 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Lactamase_B PF00753.22 CDJ62852.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF3043 PF11241.3 CDJ62852.1 - 0.16 11.5 0.3 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Pol_alpha_B_N PF08418.5 CDJ62852.1 - 0.23 10.9 4.6 0.35 10.3 3.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ribosomal_60s PF00428.14 CDJ62852.1 - 1.2 9.6 56.6 0.57 10.6 4.0 4.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein Acyl_transf_3 PF01757.17 CDJ62852.1 - 1.6 7.4 12.6 3.1 6.5 8.7 1.4 1 0 0 1 1 1 0 Acyltransferase family CAF-1_p150 PF11600.3 CDJ62852.1 - 3.6 6.9 12.7 5.4 6.3 8.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 CDJ62852.1 - 4.6 5.4 10.0 6.6 4.8 6.9 1.2 1 0 0 1 1 1 0 Transmembrane protein SMC_N PF02463.14 CDJ62853.1 - 1.1e-17 64.0 27.0 3.3e-17 62.4 18.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain UCH_1 PF13423.1 CDJ62855.1 - 7e-06 25.6 0.6 9.8e-06 25.2 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 CDJ62855.1 - 0.00011 21.4 0.2 0.00024 20.3 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase APC_CDC26 PF10471.4 CDJ62856.1 - 0.052 14.2 20.3 0.13 13.0 0.6 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Pex14_N PF04695.8 CDJ62856.1 - 0.11 12.5 12.6 0.7 9.9 4.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.3 CDJ62856.1 - 0.19 10.4 27.3 0.094 11.4 4.7 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 UCH PF00443.24 CDJ62857.1 - 3.1e-28 98.6 0.0 4.6e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDJ62857.1 - 7.7e-06 25.5 0.3 1.4e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TMEM51 PF15345.1 CDJ62857.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ribosomal_60s PF00428.14 CDJ62857.1 - 1.6 9.1 35.3 0.046 14.1 3.0 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein FCP1_C PF09309.5 CDJ62858.1 - 0.49 9.6 12.7 6.2 6.0 0.9 3.1 3 0 0 3 3 3 0 FCP1, C-terminal DUF3726 PF12525.3 CDJ62858.1 - 0.82 9.5 3.6 1.5 8.6 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3726) APC_CDC26 PF10471.4 CDJ62858.1 - 0.99 10.1 32.0 2.4 8.9 4.6 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 RAB3GAP2_N PF14655.1 CDJ62858.1 - 1.1 8.2 17.1 0.18 10.8 1.7 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus OmpH PF03938.9 CDJ62858.1 - 3.8 7.4 28.5 1.5 8.7 12.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1840 PF08895.6 CDJ62858.1 - 4.1 7.4 11.1 1.3 9.1 2.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) DUF3371 PF11851.3 CDJ62858.1 - 8 7.1 23.1 3.7 8.2 1.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) Mlo PF03094.10 CDJ62859.1 - 1.5e-06 26.5 3.3 1.3e-05 23.5 1.3 2.6 2 1 0 2 2 2 1 Mlo family EF-hand_1 PF00036.27 CDJ62859.1 - 2.6e-05 23.1 0.0 0.0044 16.2 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CDJ62859.1 - 7.2e-05 22.3 0.0 0.0081 15.9 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CDJ62859.1 - 0.00013 22.0 0.1 0.006 16.6 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CDJ62859.1 - 0.018 14.3 0.1 0.32 10.4 0.0 2.7 2 0 0 2 2 2 0 EF hand Ribosomal_L16 PF00252.13 CDJ62861.1 - 5.3e-17 61.8 0.0 7.6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rhabdo_ncap PF00945.13 CDJ62863.1 - 0.075 11.6 2.9 0.24 9.9 2.0 1.8 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2626 PF11117.3 CDJ62864.1 - 0.2 12.0 1.7 4.4 7.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2626) zf-CCCH PF00642.19 CDJ62865.1 - 6.1e-10 38.5 13.2 2.6e-05 23.7 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CDJ62865.1 - 4.5e-09 36.0 0.0 7.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ62865.1 - 4.2e-05 23.0 0.0 8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ62865.1 - 0.031 14.2 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.13 CDJ62866.1 - 2.2e-20 73.0 2.5 4.6e-20 72.0 1.7 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CDJ62866.1 - 0.0092 16.3 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain Mon1 PF03164.9 CDJ62868.1 - 1.2e-25 90.0 0.0 2.2e-08 33.1 0.0 3.1 1 1 2 3 3 3 3 Trafficking protein Mon1 InvH PF04741.7 CDJ62868.1 - 0.16 11.7 1.6 0.33 10.7 0.2 2.1 2 0 0 2 2 2 0 InvH outer membrane lipoprotein Brix PF04427.13 CDJ62869.1 - 1.5e-33 116.1 0.0 2.1e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain SelP_N PF04592.9 CDJ62869.1 - 2.4 7.4 9.4 4 6.7 6.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FCH PF00611.18 CDJ62874.1 - 0.017 15.3 0.1 0.087 13.0 0.0 2.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Tubulin PF00091.20 CDJ62875.1 - 4.9e-71 238.9 0.0 6.7e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDJ62875.1 - 1.5e-29 102.6 0.0 2.5e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CDJ62875.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 CDJ62875.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin like TRAPPC-Trs85 PF12739.2 CDJ62876.1 - 0.0045 15.7 1.3 0.0054 15.4 0.9 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit E7 PF00527.13 CDJ62876.1 - 1 9.5 4.5 1.7 8.8 0.5 2.5 2 0 0 2 2 2 0 E7 protein, Early protein Vps39_2 PF10367.4 CDJ62876.1 - 3.4 7.8 6.3 0.44 10.7 1.0 2.0 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Methyltransf_23 PF13489.1 CDJ62877.1 - 1.5e-14 54.0 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ62877.1 - 1.6e-12 47.7 0.0 3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ62877.1 - 6.3e-10 39.6 0.1 1.3e-09 38.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ62877.1 - 2e-09 37.7 0.0 4.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ62877.1 - 1.1e-07 32.1 0.1 2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ62877.1 - 9.6e-06 25.2 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ62877.1 - 3.9e-05 23.6 2.7 0.00034 20.6 1.9 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDJ62877.1 - 0.0012 18.2 0.3 0.012 15.0 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain NodS PF05401.6 CDJ62877.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 CDJ62877.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CDJ62877.1 - 0.022 13.8 0.0 0.044 12.8 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FHA PF00498.21 CDJ62878.1 - 1e-09 38.3 0.0 2.8e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 FHA domain HBS1_N PF08938.5 CDJ62878.1 - 0.0088 16.1 0.1 0.018 15.1 0.1 1.7 1 0 0 1 1 1 1 HBS1 N-terminus Peptidase_S46 PF10459.4 CDJ62878.1 - 0.012 14.0 23.2 0.016 13.6 16.1 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3357 PF11837.3 CDJ62879.1 - 0.0073 16.1 0.5 0.0073 16.1 0.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3357) DcuC PF03606.10 CDJ62879.1 - 0.13 10.5 0.1 0.21 9.7 0.0 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier CD20 PF04103.10 CDJ62879.1 - 0.3 11.0 0.6 0.76 9.6 0.0 1.9 2 0 0 2 2 2 0 CD20-like family EF-hand_1 PF00036.27 CDJ62880.1 - 3.8e-33 110.2 14.5 4.7e-09 34.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDJ62880.1 - 6.1e-29 99.9 6.6 1.2e-14 54.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDJ62880.1 - 1.8e-28 95.8 8.6 2.1e-09 36.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CDJ62880.1 - 1.2e-22 79.2 10.8 2.3e-14 52.7 0.6 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CDJ62880.1 - 3.8e-20 70.2 12.5 1e-05 24.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CDJ62880.1 - 6.3e-15 54.8 0.0 6.3e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CDJ62880.1 - 7.1e-05 22.4 3.6 0.37 10.5 0.2 3.2 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.7 CDJ62880.1 - 0.0047 15.3 0.1 0.46 8.7 0.0 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) SPARC_Ca_bdg PF10591.4 CDJ62880.1 - 0.026 14.5 0.0 4.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Acetyltransf_11 PF13720.1 CDJ62880.1 - 0.031 14.5 0.1 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 MerR-DNA-bind PF09278.6 CDJ62880.1 - 0.06 13.7 0.2 0.73 10.2 0.0 2.4 2 0 0 2 2 2 0 MerR, DNA binding SRI PF08236.6 CDJ62880.1 - 0.075 12.9 0.1 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Toprim_2 PF13155.1 CDJ62880.1 - 0.079 13.2 1.4 16 5.8 0.2 2.7 1 1 2 3 3 3 0 Toprim-like DUF21 PF01595.15 CDJ62880.1 - 0.28 10.4 1.8 0.44 9.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF21 MgtE_N PF03448.12 CDJ62880.1 - 0.43 10.9 3.9 0.21 11.9 0.3 2.2 3 0 0 3 3 3 0 MgtE intracellular N domain EF-hand_10 PF14788.1 CDJ62880.1 - 0.52 10.0 3.0 1.3 8.7 0.4 2.4 3 0 0 3 3 3 0 EF hand DAGK_acc PF00609.14 CDJ62881.1 - 2.8e-30 105.6 0.0 2.1e-14 54.0 0.0 2.9 2 1 1 3 3 3 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CDJ62881.1 - 4.5e-20 71.4 0.0 3.6e-13 49.0 0.0 2.5 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 CDJ62881.1 - 2.1e-11 43.3 25.5 8.9e-09 34.9 1.3 2.8 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pinin_SDK_memA PF04696.8 CDJ62882.1 - 2.5e-09 36.7 9.1 2.5e-09 36.7 6.3 1.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region zf-CCHC_3 PF13917.1 CDJ62883.1 - 0.006 16.2 0.2 0.006 16.2 0.2 2.4 1 1 1 2 2 2 1 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ62883.1 - 0.04 13.9 6.8 0.092 12.8 4.7 1.6 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC PF00098.18 CDJ62883.1 - 2 8.4 10.8 0.83 9.6 1.5 2.4 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 CDJ62884.1 - 9.3e-19 67.6 0.0 1.8e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hema_stalk PF08720.5 CDJ62889.1 - 0.029 13.8 0.5 0.07 12.6 0.4 1.6 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Sybindin PF04099.7 CDJ62892.1 - 9e-29 100.0 0.0 1.8e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Sybindin-like family Sec16_C PF12931.2 CDJ62892.1 - 2.4e-16 60.3 0.2 2.4e-16 60.3 0.1 3.2 3 1 0 3 3 3 1 Sec23-binding domain of Sec16 Sedlin_N PF04628.8 CDJ62892.1 - 5e-06 26.4 0.0 1.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF2815 PF10991.3 CDJ62894.1 - 0.0069 15.9 1.6 1.2 8.6 0.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2815) GAS PF13851.1 CDJ62894.1 - 0.03 13.5 14.3 0.013 14.7 7.1 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding RHH_1 PF01402.16 CDJ62894.1 - 0.068 13.0 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Herpes_UL6 PF01763.11 CDJ62894.1 - 0.17 9.9 5.9 0.23 9.5 4.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like GCD14 PF08704.5 CDJ62894.1 - 0.22 10.9 4.3 0.34 10.3 3.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Mnd1 PF03962.10 CDJ62894.1 - 1.6 8.3 13.3 0.073 12.7 4.9 1.8 2 0 0 2 2 2 0 Mnd1 family DUF4600 PF15372.1 CDJ62894.1 - 1.6 8.9 12.7 3.5 7.8 8.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Seryl_tRNA_N PF02403.17 CDJ62894.1 - 3.3 7.7 11.8 1 9.4 4.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SprA-related PF12118.3 CDJ62894.1 - 4.5 6.5 13.2 7.1 5.8 9.2 1.3 1 0 0 1 1 1 0 SprA-related family CDC37_N PF03234.9 CDJ62894.1 - 5.5 7.2 11.6 1.6 8.9 5.1 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF1930 PF09122.5 CDJ62895.1 - 0.0045 16.7 0.1 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) BUD22 PF09073.5 CDJ62895.1 - 0.011 14.7 25.0 0.013 14.6 17.3 1.1 1 0 0 1 1 1 0 BUD22 Pol_alpha_B_N PF08418.5 CDJ62895.1 - 0.86 9.0 16.0 1.3 8.4 11.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal U3_assoc_6 PF08640.6 CDJ62896.1 - 2.6e-09 36.6 3.2 2.6e-09 36.6 2.2 2.5 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DUF755 PF05501.6 CDJ62896.1 - 2.7e-05 24.2 30.8 0.00011 22.2 8.6 15.0 13 2 1 14 14 14 3 Domain of unknown function (DUF755) TPR_14 PF13428.1 CDJ62896.1 - 0.00018 21.8 3.4 0.00018 21.8 2.3 8.7 8 2 2 10 10 10 3 Tetratricopeptide repeat Ribosomal_60s PF00428.14 CDJ62896.1 - 0.0027 18.0 7.4 0.0027 18.0 5.2 6.5 6 0 0 6 6 6 2 60s Acidic ribosomal protein Bap31 PF05529.7 CDJ62897.1 - 0.0039 16.6 0.7 0.0082 15.6 0.4 1.6 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF4636 PF15468.1 CDJ62897.1 - 0.047 13.1 0.4 0.069 12.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF2681 PF10883.3 CDJ62897.1 - 0.068 13.3 0.3 0.17 12.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) F-box-like PF12937.2 CDJ62898.1 - 0.0012 18.5 2.9 0.0012 18.5 2.0 1.9 2 0 0 2 2 2 1 F-box-like Pex14_N PF04695.8 CDJ62898.1 - 1.2 9.1 28.8 0.84 9.6 7.0 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA PF00004.24 CDJ62899.1 - 2.1e-14 53.8 0.0 2.1e-14 53.8 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SR-25 PF10500.4 CDJ62899.1 - 0.00052 19.5 16.2 0.00052 19.5 11.2 10.2 9 2 0 9 9 9 3 Nuclear RNA-splicing-associated protein AAA_33 PF13671.1 CDJ62899.1 - 0.0095 15.8 0.0 0.0095 15.8 0.0 4.4 4 1 0 4 4 4 1 AAA domain zf-DHHC PF01529.15 CDJ62899.1 - 0.088 12.2 4.2 0.033 13.5 0.4 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase AAA_17 PF13207.1 CDJ62899.1 - 0.09 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDJ62899.1 - 0.49 10.5 0.0 0.49 10.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF3801 PF12687.2 CDJ62899.1 - 1.2 8.6 18.9 0.054 13.0 2.8 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3801) EB1 PF03271.12 CDJ62900.1 - 3.3e-11 43.0 0.0 9.3e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif Med15 PF09606.5 CDJ62900.1 - 0.0023 16.2 14.0 0.0027 16.0 9.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.1 CDJ62900.1 - 0.061 12.2 4.8 0.07 12.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.8 CDJ62900.1 - 0.39 10.5 11.7 0.52 10.1 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LPP20 PF02169.11 CDJ62900.1 - 1.8 8.7 9.8 0.13 12.3 2.7 1.9 1 1 1 2 2 2 0 LPP20 lipoprotein DUF2477 PF10631.4 CDJ62900.1 - 8.3 6.6 9.9 17 5.5 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) DUF3661 PF12400.3 CDJ62901.1 - 3.6e-05 23.8 0.0 6.8e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Vaculolar membrane protein SR-25 PF10500.4 CDJ62901.1 - 2.6 7.4 21.3 1.1 8.7 5.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Surface_antigen PF11054.3 CDJ62902.1 - 3.1e-83 279.0 1.0 3.4e-83 278.9 0.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62903.1 - 3.8e-83 278.7 0.1 4.3e-83 278.6 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62904.1 - 2.3e-68 230.3 0.2 2.5e-56 190.9 0.0 2.1 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ62905.1 - 2e-70 237.0 0.2 2.8e-70 236.6 0.2 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen FYRC PF05965.9 CDJ62905.1 - 0.0055 16.4 0.1 0.77 9.6 0.0 2.4 2 1 0 2 2 2 2 F/Y rich C-terminus Surface_antigen PF11054.3 CDJ62906.1 - 3.3e-78 262.6 0.7 3.6e-78 262.4 0.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Peripla_BP_5 PF13433.1 CDJ62906.1 - 0.04 12.6 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Surface_antigen PF11054.3 CDJ62907.1 - 7.5e-82 274.5 0.4 8.2e-82 274.3 0.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Chromo PF00385.19 CDJ62908.1 - 2e-14 52.9 0.2 3.2e-13 49.1 0.0 2.6 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 CDJ62908.1 - 0.001 19.0 0.1 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Metal_resist PF13801.1 CDJ62910.1 - 0.0052 16.7 0.6 0.0052 16.7 0.4 1.6 2 0 0 2 2 2 1 Heavy-metal resistance IF-2 PF11987.3 CDJ62911.1 - 6.1e-21 74.3 0.8 7.6e-21 74.0 0.5 1.1 1 0 0 1 1 1 1 Translation-initiation factor 2 RNA_helicase PF00910.17 CDJ62914.1 - 0.00039 20.5 1.2 0.00076 19.6 0.0 2.1 2 1 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 CDJ62914.1 - 0.0056 16.6 0.0 0.02 14.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ycf1 PF05758.7 CDJ62914.1 - 1.4 6.5 25.4 0.011 13.4 3.3 2.6 3 0 0 3 3 3 0 Ycf1 Zip PF02535.17 CDJ62914.1 - 2.1 7.2 6.5 0.24 10.3 1.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter ROK PF00480.15 CDJ62915.1 - 0.078 12.7 0.5 0.11 12.3 0.4 1.1 1 0 0 1 1 1 0 ROK family DUF4614 PF15391.1 CDJ62915.1 - 0.51 10.0 10.3 0.72 9.5 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.4 CDJ62915.1 - 0.61 8.3 13.4 0.44 8.7 0.2 2.1 2 0 0 2 2 2 0 Transmembrane protein VIT1 PF01988.14 CDJ62915.1 - 0.69 9.3 9.4 0.98 8.8 6.5 1.2 1 0 0 1 1 1 0 VIT family DUF677 PF05055.7 CDJ62915.1 - 4.1 5.9 8.9 6.3 5.3 6.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF677) SR-25 PF10500.4 CDJ62915.1 - 4.5 6.6 22.2 0.87 9.0 12.5 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TBPIP PF07106.8 CDJ62916.1 - 2.1 7.8 4.8 1.8 8.0 1.6 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AMP-binding PF00501.23 CDJ62917.1 - 9.8e-10 37.3 1.1 1.8e-05 23.3 0.1 2.9 2 1 0 2 2 2 2 AMP-binding enzyme PHD_3 PF13922.1 CDJ62917.1 - 3.4 7.9 7.0 64 3.9 4.8 3.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx eIF3_p135 PF12807.2 CDJ62920.1 - 1.5e-09 37.9 13.4 1.9e-07 31.1 0.0 5.2 5 0 0 5 5 5 2 Translation initiation factor eIF3 subunit 135 CLU PF13236.1 CDJ62920.1 - 4.5e-06 26.2 0.6 0.00031 20.2 0.1 3.0 2 0 0 2 2 2 2 Clustered mitochondria Asp_protease_2 PF13650.1 CDJ62921.1 - 2.7e-11 43.8 0.0 6.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CDJ62921.1 - 6.4e-11 42.0 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CDJ62921.1 - 3.4e-09 36.3 0.0 8.3e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ62921.1 - 5.1e-07 29.5 0.0 2.7e-06 27.2 0.0 2.2 2 1 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ62921.1 - 8e-06 25.8 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CDJ62921.1 - 1e-05 25.5 0.0 3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease PF09668.5 CDJ62921.1 - 0.0045 16.5 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF3552 PF12072.3 CDJ62921.1 - 0.012 14.7 0.8 0.02 14.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PNK3P PF08645.6 CDJ62924.1 - 0.011 15.2 0.3 0.021 14.2 0.2 1.5 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.1 CDJ62924.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ62924.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 CDJ62924.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Acid_PPase PF12689.2 CDJ62924.1 - 0.14 11.8 0.7 0.23 11.0 0.5 1.5 1 1 0 1 1 1 0 Acid Phosphatase SAGA-Tad1 PF12767.2 CDJ62926.1 - 0.58 9.7 5.4 0.35 10.4 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit SSB PF00436.20 CDJ62927.1 - 6.3e-32 109.5 0.1 8.5e-32 109.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family RNA_Me_trans PF04252.8 CDJ62928.1 - 3.2e-29 101.7 0.0 4e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase CPW_WPC PF09717.5 CDJ62929.1 - 0.0023 18.5 0.0 0.25 11.9 0.2 2.2 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) Herpes_env PF01673.13 CDJ62930.1 - 0.047 12.2 18.1 0.053 12.0 12.6 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF4045 PF13254.1 CDJ62930.1 - 0.14 11.4 21.5 0.17 11.1 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GAGA_bind PF06217.7 CDJ62930.1 - 0.32 10.8 23.6 0.37 10.7 16.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 CDJ62930.1 - 0.37 8.7 23.0 0.41 8.6 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CDJ62930.1 - 0.45 8.1 23.7 0.53 7.9 16.4 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CDJ62930.1 - 0.77 9.5 22.8 0.96 9.2 15.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_UL87 PF03043.9 CDJ62930.1 - 0.88 7.8 19.5 1 7.6 13.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Bud13 PF09736.4 CDJ62930.1 - 1 9.6 29.2 1.5 9.0 20.2 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex AUX_IAA PF02309.11 CDJ62930.1 - 1 9.0 20.3 1.4 8.6 14.1 1.3 1 0 0 1 1 1 0 AUX/IAA family AvrE PF11725.3 CDJ62930.1 - 1.1 6.1 28.4 1.2 6.1 19.7 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF1510 PF07423.6 CDJ62930.1 - 1.1 8.5 24.1 1.6 8.0 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NARP1 PF12569.3 CDJ62930.1 - 1.4 7.6 26.5 1.6 7.3 18.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF-3_zeta PF05091.7 CDJ62930.1 - 1.7 7.1 29.0 2.5 6.6 20.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDJ62930.1 - 2.1 6.4 72.0 2.5 6.2 49.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDJ62930.1 - 2.3 5.7 29.4 2.6 5.5 20.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.14 CDJ62930.1 - 2.7 7.6 23.5 3.4 7.3 16.3 1.3 1 0 0 1 1 1 0 SPX domain Parvo_coat PF00740.13 CDJ62930.1 - 2.8 6.7 29.7 3.5 6.4 20.6 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FLO_LFY PF01698.11 CDJ62930.1 - 3.3 6.4 23.0 4.1 6.1 15.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein CRT10 PF08728.5 CDJ62930.1 - 6.1 4.7 17.9 6.8 4.5 12.4 1.0 1 0 0 1 1 1 0 CRT10 Med15 PF09606.5 CDJ62930.1 - 8 4.5 91.9 9.7 4.2 63.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PLRV_ORF5 PF01690.12 CDJ62930.1 - 8.7 5.3 25.6 10 5.1 17.7 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein GPCR_chapero_1 PF11904.3 CDJ62930.1 - 9 5.3 27.5 12 4.9 19.1 1.1 1 0 0 1 1 1 0 GPCR-chaperone Pox_Ag35 PF03286.9 CDJ62930.1 - 9.9 5.6 15.2 15 5.0 10.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_60s PF00428.14 CDJ62931.1 - 0.41 11.0 14.4 0.13 12.7 3.6 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein PCNA_N PF00705.13 CDJ62932.1 - 1.4e-22 79.5 0.1 3.8e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain UPF0564 PF10595.4 CDJ62932.1 - 0.098 11.5 26.6 0.12 11.2 18.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF940 PF06082.6 CDJ62932.1 - 0.21 10.0 10.1 0.28 9.6 7.0 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Hid1 PF12722.2 CDJ62932.1 - 0.26 8.8 15.0 0.35 8.5 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_23 PF13476.1 CDJ62932.1 - 0.6 10.4 18.6 0.98 9.7 12.9 1.4 1 0 0 1 1 1 0 AAA domain DUF4045 PF13254.1 CDJ62932.1 - 0.93 8.7 11.3 1.2 8.3 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDJ62932.1 - 1.1 7.3 53.4 1.5 6.9 37.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF342 PF03961.8 CDJ62932.1 - 1.7 7.0 11.8 2.3 6.5 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mgr1 PF08602.5 CDJ62932.1 - 2.8 6.8 9.0 4.3 6.2 6.2 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF3450 PF11932.3 CDJ62932.1 - 3 7.0 39.4 5.2 6.2 27.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Astro_capsid PF03115.9 CDJ62932.1 - 4.5 5.4 14.4 5.7 5.0 10.0 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Exonuc_VII_L PF02601.10 CDJ62932.1 - 5.7 6.0 21.5 7.7 5.6 14.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HlyD_2 PF12700.2 CDJ62932.1 - 5.9 5.9 14.1 8.3 5.4 9.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Tho2 PF11262.3 CDJ62932.1 - 6 5.8 21.5 9.8 5.1 14.9 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 VPEP PF07589.6 CDJ62933.1 - 0.29 11.0 4.4 1.7 8.6 3.0 2.4 1 0 0 1 1 1 0 PEP-CTERM motif Claudin_2 PF13903.1 CDJ62934.1 - 1.2 8.7 0.0 1.2 8.7 0.0 3.0 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction DUF202 PF02656.10 CDJ62934.1 - 1.5 9.1 9.0 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Glyco_hydro_35 PF01301.14 CDJ62938.1 - 1.5e-07 31.0 0.0 1.5e-07 31.0 0.0 4.5 5 0 0 5 5 5 1 Glycosyl hydrolases family 35 Macoilin PF09726.4 CDJ62938.1 - 3.2e-05 22.4 19.3 3.2e-05 22.4 13.4 6.3 4 3 1 5 5 5 1 Transmembrane protein DUF1645 PF07816.6 CDJ62938.1 - 0.00029 21.3 4.6 0.00029 21.3 3.2 9.9 7 2 0 8 8 8 2 Protein of unknown function (DUF1645) SR-25 PF10500.4 CDJ62938.1 - 0.00062 19.2 15.1 0.00062 19.2 10.5 11.0 9 3 1 10 10 10 4 Nuclear RNA-splicing-associated protein Ndc1_Nup PF09531.5 CDJ62938.1 - 4.1 5.7 0.0 4.1 5.7 0.0 6.2 5 1 1 6 6 6 0 Nucleoporin protein Ndc1-Nup Spc7 PF08317.6 CDJ62939.1 - 0.00081 18.1 7.7 0.001 17.8 5.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Streptin-Immun PF11083.3 CDJ62939.1 - 0.019 14.9 1.1 0.031 14.2 0.7 1.3 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein HAUS-augmin3 PF14932.1 CDJ62939.1 - 0.077 12.1 8.2 0.1 11.7 5.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF812 PF05667.6 CDJ62939.1 - 0.18 10.2 8.2 0.23 9.9 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.3 CDJ62939.1 - 0.26 11.1 8.8 0.38 10.6 6.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.4 CDJ62939.1 - 0.79 8.8 8.9 0.98 8.5 6.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Atg14 PF10186.4 CDJ62939.1 - 1.3 7.9 9.4 0.14 11.0 3.3 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 CDJ62939.1 - 1.6 7.0 6.8 2 6.7 4.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain APG6 PF04111.7 CDJ62939.1 - 2.3 7.1 10.2 2.9 6.8 7.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CDJ62939.1 - 6.1 6.4 10.0 11 5.6 4.5 2.1 2 0 0 2 2 2 0 IncA protein HEAT PF02985.17 CDJ62940.1 - 0.0048 16.8 4.7 0.03 14.4 0.1 4.2 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.18 CDJ62940.1 - 0.084 12.7 1.6 0.64 9.9 0.2 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDJ62940.1 - 0.21 11.8 15.1 5.5e+02 0.9 10.3 3.4 1 1 0 1 1 1 0 HEAT repeats CDK2AP PF09806.4 CDJ62940.1 - 0.43 10.7 7.5 0.84 9.8 0.2 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein HEAT_EZ PF13513.1 CDJ62940.1 - 4.5 7.8 16.5 1.3 9.5 0.1 4.1 3 1 0 3 3 3 0 HEAT-like repeat PUB PF09409.5 CDJ62941.1 - 4.4e-15 55.2 0.0 1.5e-14 53.5 0.0 2.0 1 0 0 1 1 1 1 PUB domain Mitofilin PF09731.4 CDJ62941.1 - 8.7e-07 27.9 37.5 1.5e-05 23.9 12.0 2.1 2 0 0 2 2 2 2 Mitochondrial inner membrane protein PAT1 PF09770.4 CDJ62941.1 - 0.0019 16.5 40.6 0.0019 16.5 28.2 2.2 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDJ62941.1 - 0.015 13.6 18.7 0.069 11.4 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein Ycf1 PF05758.7 CDJ62941.1 - 1.8 6.1 31.3 0.19 9.4 0.1 2.1 2 0 0 2 2 2 0 Ycf1 SAPS PF04499.10 CDJ62941.1 - 6.5 5.2 31.2 0.24 10.0 0.5 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RRP7 PF12923.2 CDJ62942.1 - 8.4e-14 51.7 4.1 6.7e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CDJ62942.1 - 0.1 12.2 0.0 0.41 10.3 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NEMO PF11577.3 CDJ62942.1 - 0.31 10.8 3.1 0.56 9.9 2.2 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Neur_chan_memb PF02932.11 CDJ62943.1 - 0.03 14.2 1.1 12 5.6 1.4 3.1 2 2 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_S6e PF01092.14 CDJ62945.1 - 4.1e-53 178.3 0.2 7.8e-53 177.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e MSP1_C PF07462.6 CDJ62945.1 - 0.041 12.2 1.6 0.062 11.6 1.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Baculo_p24 PF05073.7 CDJ62946.1 - 0.63 9.5 2.1 1.2 8.7 1.5 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein SR-25 PF10500.4 CDJ62947.1 - 0.0068 15.8 2.9 0.0068 15.8 2.0 3.2 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Pyr_redox_3 PF13738.1 CDJ62948.1 - 0.0043 17.1 0.0 0.0062 16.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Symplekin_C PF12295.3 CDJ62950.1 - 1.3e-27 96.8 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal WD40 PF00400.27 CDJ62951.1 - 6.3e-11 41.7 9.7 0.072 13.0 0.0 5.1 5 1 0 5 5 5 4 WD domain, G-beta repeat RVT_1 PF00078.22 CDJ62952.1 - 9.5e-07 28.3 0.0 2.2e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SBDS PF01172.13 CDJ62953.1 - 7.1e-26 89.8 0.0 1.6e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 CDJ62953.1 - 9.1e-17 60.9 0.0 9.1e-17 60.9 0.0 2.4 2 0 0 2 2 2 1 SBDS protein C-terminal domain GDI PF00996.13 CDJ62954.1 - 2.1e-198 659.0 0.0 2.4e-198 658.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DAO PF01266.19 CDJ62954.1 - 0.03 13.2 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase rve PF00665.21 CDJ62955.1 - 4.3e-13 49.4 0.0 6.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ62955.1 - 0.053 13.0 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain CAF-1_p150 PF11600.3 CDJ62958.1 - 0.017 14.5 19.5 0.019 14.3 13.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MMR1 PF08505.5 CDJ62958.1 - 3.7 7.5 12.5 4.3 7.2 8.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4647 PF15504.1 CDJ62958.1 - 5.1 5.8 16.1 6.2 5.5 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) U79_P34 PF03064.11 CDJ62958.1 - 5.2 6.5 15.8 6.8 6.1 10.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ribosomal_L13 PF00572.13 CDJ62959.1 - 7e-25 87.5 0.2 7e-25 87.5 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 UPF0542 PF15086.1 CDJ62961.1 - 0.034 13.8 0.3 0.034 13.8 0.2 2.7 4 0 0 4 4 4 0 Uncharacterised protein family UPF0542 RF-1 PF00472.15 CDJ62962.1 - 3.4e-19 68.7 12.4 1.2e-18 66.9 0.3 3.3 2 1 1 3 3 3 2 RF-1 domain PCRF PF03462.13 CDJ62962.1 - 0.43 10.3 4.7 22 4.7 3.3 2.6 1 1 0 1 1 1 0 PCRF domain RAP1 PF07218.6 CDJ62963.1 - 0.068 11.2 9.9 0.12 10.4 6.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ETRAMP PF09716.5 CDJ62964.1 - 0.095 12.6 1.5 8.7 6.3 0.0 3.4 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Asp_protease_2 PF13650.1 CDJ62968.1 - 2.4e-09 37.5 0.0 4.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ62968.1 - 3e-08 33.3 0.0 6.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ62968.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ62968.1 - 0.0013 18.7 0.0 0.01 15.8 0.0 2.4 3 0 0 3 3 3 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ62968.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.21 CDJ62969.1 - 1.3e-13 51.0 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain GLTSCR1 PF15249.1 CDJ62969.1 - 0.078 13.0 0.1 0.19 11.8 0.1 1.7 1 1 0 1 1 1 0 Glioma tumor suppressor candidate region Ribosomal_60s PF00428.14 CDJ62971.1 - 0.0082 16.5 10.6 0.011 16.0 7.4 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF755 PF05501.6 CDJ62971.1 - 0.13 12.3 28.9 0.17 11.9 20.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Zwint PF15556.1 CDJ62971.1 - 0.18 11.0 35.4 0.2 10.8 24.5 1.0 1 0 0 1 1 1 0 ZW10 interactor SpoIIP PF07454.6 CDJ62971.1 - 0.24 10.5 9.9 0.28 10.3 6.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Plasmodium_Vir PF05795.6 CDJ62971.1 - 0.94 8.6 5.4 1.1 8.4 3.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GPCR_chapero_1 PF11904.3 CDJ62971.1 - 1.1 8.3 13.9 1.4 7.9 9.6 1.3 1 0 0 1 1 1 0 GPCR-chaperone Poxvirus_B22R_N PF13169.1 CDJ62971.1 - 1.5 9.0 7.5 1 9.6 3.8 1.7 1 1 1 2 2 2 0 Poxvirus B22R protein N-terminal DUF4175 PF13779.1 CDJ62971.1 - 1.6 6.3 41.9 1.7 6.2 29.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SPOUT_MTase PF02590.12 CDJ62971.1 - 1.8 8.2 9.0 2.5 7.8 6.2 1.1 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase PTPlike_phytase PF14566.1 CDJ62971.1 - 2.3 8.2 6.8 2.4 8.2 4.7 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF572 PF04502.8 CDJ62971.1 - 2.8 7.0 19.4 3 6.9 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DDRGK PF09756.4 CDJ62971.1 - 3.1 7.1 21.1 3.4 7.0 14.6 1.1 1 0 0 1 1 1 0 DDRGK domain Draxin PF15550.1 CDJ62971.1 - 3.7 7.1 11.9 3.8 7.0 8.2 1.0 1 0 0 1 1 1 0 Draxin Mem_trans PF03547.13 CDJ62971.1 - 3.7 5.7 9.7 4.1 5.6 6.8 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF3533 PF12051.3 CDJ62971.1 - 5.4 5.6 12.0 6.2 5.4 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Fmp27_WPPW PF10359.4 CDJ62971.1 - 6.6 5.0 17.9 7.5 4.8 12.4 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4638 PF15472.1 CDJ62971.1 - 8 5.9 11.5 8.5 5.8 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) FAM60A PF15396.1 CDJ62971.1 - 8 6.1 11.8 10 5.8 8.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Membralin PF09746.4 CDJ62971.1 - 8.6 5.2 8.2 8.4 5.3 5.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein RNA_pol_Rpb1_2 PF00623.15 CDJ62971.1 - 8.8 6.2 8.9 11 5.9 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Exonuc_VII_L PF02601.10 CDJ62971.1 - 9.6 5.2 19.0 11 5.0 13.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDC73 PF05179.9 CDJ62971.1 - 9.7 5.4 16.2 11 5.2 11.2 1.0 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family NAD_binding_1 PF00175.16 CDJ62972.1 - 1.8e-07 31.6 10.6 1.9e-07 31.6 2.5 3.5 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Isy1 PF06246.7 CDJ62972.1 - 0.00011 21.6 7.7 0.00028 20.3 0.2 2.2 2 0 0 2 2 2 1 Isy1-like splicing family Spt20 PF12090.3 CDJ62972.1 - 0.00023 20.5 12.5 0.022 14.0 0.3 2.8 3 0 0 3 3 3 2 Spt20 family SGT1 PF07093.6 CDJ62972.1 - 0.011 14.1 9.5 0.11 10.8 1.4 2.2 2 0 0 2 2 2 0 SGT1 protein FPN1 PF06963.7 CDJ62972.1 - 0.013 13.9 4.0 0.36 9.1 0.7 2.1 2 0 0 2 2 2 0 Ferroportin1 (FPN1) FCP1_C PF09309.5 CDJ62972.1 - 0.026 13.8 12.3 0.18 11.0 0.9 2.4 2 0 0 2 2 2 0 FCP1, C-terminal PIG-P PF08510.7 CDJ62972.1 - 0.034 13.7 0.4 0.57 9.8 0.1 2.1 2 0 0 2 2 2 0 PIG-P NAD_binding_6 PF08030.7 CDJ62972.1 - 0.044 13.6 5.7 0.15 11.9 0.3 2.7 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Peptidase_S49_N PF08496.5 CDJ62972.1 - 0.072 12.8 0.3 0.072 12.8 0.2 2.5 3 0 0 3 3 2 0 Peptidase family S49 N-terminal DUF3617 PF12276.3 CDJ62972.1 - 0.078 12.4 17.2 0.038 13.4 4.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) CPSF100_C PF13299.1 CDJ62972.1 - 0.097 12.8 4.5 4.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.10 CDJ62972.1 - 0.1 11.3 5.8 1 8.0 1.1 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) Suf PF05843.9 CDJ62972.1 - 0.11 12.2 18.6 0.059 13.0 2.4 2.4 3 0 0 3 3 2 0 Suppressor of forked protein (Suf) zf-DHHC PF01529.15 CDJ62972.1 - 0.12 11.7 6.5 5 6.4 0.2 3.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase Ctr PF04145.10 CDJ62972.1 - 0.14 12.2 6.7 4.1 7.4 0.1 2.6 2 1 0 2 2 2 0 Ctr copper transporter family RAB3GAP2_N PF14655.1 CDJ62972.1 - 0.19 10.7 18.6 0.12 11.3 0.8 2.4 3 0 0 3 3 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1360 PF07098.6 CDJ62972.1 - 0.2 11.4 2.1 2.9 7.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) OATP PF03137.15 CDJ62972.1 - 0.37 8.7 5.6 1.1 7.2 1.4 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Rxt3 PF08642.5 CDJ62972.1 - 0.44 10.7 5.2 11 6.3 0.7 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF1517 PF07466.6 CDJ62972.1 - 0.62 8.9 12.2 0.4 9.6 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1517) XRN_N PF03159.13 CDJ62972.1 - 0.67 9.3 4.8 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus eIF_4EBP PF05456.6 CDJ62972.1 - 0.96 9.1 7.8 2.8 7.6 1.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) 7tm_1 PF00001.16 CDJ62972.1 - 1.1 8.3 4.8 6.5 5.7 0.0 2.3 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4483 PF14825.1 CDJ62972.1 - 1.6 8.3 17.5 0.1 12.2 0.8 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4483) Tsg PF04668.7 CDJ62972.1 - 1.6 8.9 9.4 1.5 9.0 3.2 2.4 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region EIIBC-GUT_N PF03612.9 CDJ62972.1 - 1.7 8.2 8.7 2.3 7.7 1.2 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4199 PF13858.1 CDJ62972.1 - 1.9 8.3 5.6 6.1 6.7 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Glt_symporter PF03616.9 CDJ62972.1 - 2.3 6.6 8.4 2.3 6.6 1.3 2.1 1 1 1 2 2 2 0 Sodium/glutamate symporter DUF912 PF06024.7 CDJ62972.1 - 2.6 8.1 9.6 6.1 6.9 2.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Baculo_PP31 PF05311.6 CDJ62972.1 - 3.7 6.7 9.5 9.7 5.3 0.4 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) ATAD4 PF15321.1 CDJ62972.1 - 4.2 8.4 12.9 3.1 8.8 0.9 3.1 4 0 0 4 4 2 0 ATPase family AAA domain containing 4 CD20 PF04103.10 CDJ62972.1 - 5.1 7.0 8.0 7.2 6.5 0.1 3.0 4 0 0 4 4 2 0 CD20-like family UPF0560 PF10577.4 CDJ62972.1 - 6.8 4.8 20.9 0.27 9.4 1.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 HemX PF04375.9 CDJ62972.1 - 6.9 5.1 32.2 0.08 11.5 8.5 2.7 3 0 0 3 3 3 0 HemX Rpp20 PF12328.3 CDJ62972.1 - 6.9 6.3 12.5 2.2 7.9 0.0 2.4 3 0 0 3 3 2 0 Rpp20 subunit of nuclear RNase MRP and P EphA2_TM PF14575.1 CDJ62972.1 - 8.3 6.8 12.8 6.4 7.2 0.2 3.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MscS_TM PF12794.2 CDJ62972.1 - 9.6 4.6 13.4 0.17 10.4 1.1 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Pet191_N PF10203.4 CDJ62973.1 - 0.08 12.9 0.2 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 IncA PF04156.9 CDJ62973.1 - 0.36 10.3 10.9 0.48 10.0 7.6 1.2 1 0 0 1 1 1 0 IncA protein TFIIA PF03153.8 CDJ62973.1 - 2.1 8.1 8.9 2.4 7.9 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDJ62973.1 - 3 5.9 12.2 3.3 5.7 8.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2894 PF11445.3 CDJ62973.1 - 3.2 7.9 16.4 4.5 7.4 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Macoilin PF09726.4 CDJ62973.1 - 6.5 4.9 13.2 7.7 4.6 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DnaJ-X PF14308.1 CDJ62974.1 - 1.5e-46 158.2 10.0 4.2e-38 130.6 2.3 2.3 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.26 CDJ62974.1 - 7e-19 67.3 0.3 1.7e-18 66.0 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain SR-25 PF10500.4 CDJ62974.1 - 1.8 7.9 21.0 0.051 13.0 9.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Chorismate_synt PF01264.16 CDJ62975.1 - 4.7e-59 199.6 1.2 7.5e-50 169.3 0.0 3.5 2 2 1 3 3 3 2 Chorismate synthase DUF4045 PF13254.1 CDJ62975.1 - 2.4 7.3 32.0 4.5 6.4 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) CDC27 PF09507.5 CDJ62976.1 - 8.5 5.4 20.0 10 5.2 13.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NYD-SP28_assoc PF14775.1 CDJ62977.1 - 0.079 12.6 0.8 0.1 12.2 0.6 1.2 1 0 0 1 1 1 0 Sperm tail C-terminal domain SR-25 PF10500.4 CDJ62977.1 - 0.15 11.5 12.4 0.15 11.5 8.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATG16 PF08614.6 CDJ62977.1 - 0.21 11.3 1.2 0.22 11.2 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF755 PF05501.6 CDJ62977.1 - 0.22 11.5 11.0 0.27 11.2 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Herpes_capsid PF06112.6 CDJ62977.1 - 0.3 11.1 5.0 0.34 10.9 3.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SSP160 PF06933.6 CDJ62977.1 - 0.51 8.2 7.7 0.52 8.2 5.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Myco_19_kDa PF05481.7 CDJ62977.1 - 0.67 9.7 4.9 0.82 9.4 3.4 1.0 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen KIAA1328 PF15369.1 CDJ62977.1 - 0.73 9.5 7.0 0.78 9.5 4.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 CAF-1_p150 PF11600.3 CDJ62977.1 - 2.2 7.5 6.3 2.5 7.4 4.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAM2 PF07145.10 CDJ62978.1 - 0.00032 19.9 1.0 0.00032 19.9 0.7 2.1 2 0 0 2 2 2 1 Ataxin-2 C-terminal region SR-25 PF10500.4 CDJ62978.1 - 0.0063 16.0 8.9 0.0063 16.0 6.2 6.7 4 1 2 6 6 6 3 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ62979.1 - 0.005 16.3 17.6 0.005 16.3 12.2 3.1 2 1 1 3 3 1 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDJ62979.1 - 0.0073 15.6 31.8 0.0094 15.3 22.0 1.1 1 0 0 1 1 1 1 SprA-related family Raftlin PF15250.1 CDJ62979.1 - 0.055 11.9 16.5 0.087 11.3 11.4 1.3 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 CDJ62979.1 - 0.069 10.8 24.7 0.086 10.5 17.1 1.2 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 CDJ62979.1 - 0.081 10.8 35.5 0.1 10.5 24.6 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CDJ62979.1 - 0.17 11.1 37.0 0.23 10.7 25.6 1.1 1 0 0 1 1 1 0 SDA1 SOBP PF15279.1 CDJ62979.1 - 2.1 8.6 12.5 2.6 8.3 8.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF966 PF06136.8 CDJ62979.1 - 2.4 7.4 23.2 3.8 6.8 16.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF936 PF06075.7 CDJ62979.1 - 4.3 6.1 23.9 4.9 5.9 16.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) CDC27 PF09507.5 CDJ62979.1 - 7.8 5.6 47.7 9.7 5.2 33.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hex_IIIa PF02455.11 CDJ62979.1 - 9.2 4.8 18.8 11 4.5 13.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Ank_2 PF12796.2 CDJ62981.1 - 6.5e-09 36.0 12.6 2e-07 31.2 0.1 3.6 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDJ62981.1 - 1.1e-06 28.9 1.2 7.3e-05 23.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDJ62981.1 - 5.8e-06 26.3 12.0 0.0033 17.6 0.0 5.3 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ62981.1 - 8.8e-05 22.3 7.8 0.027 14.7 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 CDJ62981.1 - 0.0087 15.8 17.0 0.013 15.3 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat Ribosomal_L10 PF00466.15 CDJ62982.1 - 8.7e-12 44.8 0.8 1.4e-11 44.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 SR-25 PF10500.4 CDJ62986.1 - 0.017 14.5 19.8 0.028 13.8 13.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VitD-bind_III PF09164.5 CDJ62986.1 - 0.066 12.8 1.3 0.13 11.9 0.9 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III FAM60A PF15396.1 CDJ62986.1 - 0.12 12.0 12.3 0.16 11.7 8.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4647 PF15504.1 CDJ62986.1 - 0.25 10.1 14.4 0.29 9.9 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) PLRV_ORF5 PF01690.12 CDJ62986.1 - 0.37 9.8 17.5 0.44 9.6 12.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neur_chan_memb PF02932.11 CDJ62986.1 - 0.45 10.3 8.7 0.45 10.3 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF755 PF05501.6 CDJ62986.1 - 0.46 10.5 30.7 0.66 10.0 21.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Fmp27_WPPW PF10359.4 CDJ62986.1 - 0.6 8.4 12.0 0.72 8.2 8.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF572 PF04502.8 CDJ62986.1 - 0.63 9.2 15.0 0.72 9.0 10.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 CDJ62986.1 - 1.2 6.7 15.4 1.4 6.5 10.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LCD1 PF09798.4 CDJ62986.1 - 1.5 6.7 15.0 1.8 6.4 10.4 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein HlyD_2 PF12700.2 CDJ62986.1 - 1.9 7.5 9.9 2 7.4 6.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF3573 PF12097.3 CDJ62986.1 - 2.1 6.8 11.8 2.5 6.6 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Herpes_env PF01673.13 CDJ62986.1 - 3 6.2 21.5 3.4 6.1 14.9 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Plasmodium_Vir PF05795.6 CDJ62986.1 - 4.9 6.2 7.7 6.7 5.8 5.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.5 CDJ62986.1 - 6.4 5.0 13.4 7 4.9 9.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF342 PF03961.8 CDJ62986.1 - 6.6 5.0 8.6 8.6 4.6 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SLD3 PF08639.5 CDJ62986.1 - 6.9 5.1 20.7 8.3 4.9 14.4 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 DNA_pol_viral_N PF00242.12 CDJ62986.1 - 9.2 5.1 20.0 11 4.9 13.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Glyco_transf_15 PF01793.11 CDJ62986.1 - 9.4 5.0 9.3 12 4.7 6.5 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Ycf1 PF05758.7 CDJ62986.1 - 9.6 3.7 11.6 11 3.5 8.1 1.0 1 0 0 1 1 1 0 Ycf1 TMEM18 PF14770.1 CDJ62987.1 - 2.5e-06 27.0 6.5 3e-05 23.5 4.5 2.3 1 1 0 1 1 1 1 Transmembrane protein 18 YfhO PF09586.5 CDJ62987.1 - 0.00064 17.8 1.4 0.00064 17.8 1.0 2.0 1 1 1 2 2 2 1 Bacterial membrane protein YfhO TSA PF03249.8 CDJ62987.1 - 0.0024 16.5 5.0 0.0024 16.5 3.4 3.0 3 0 0 3 3 3 1 Type specific antigen EcsB PF05975.7 CDJ62987.1 - 0.0043 15.5 4.6 0.0063 15.0 3.2 1.3 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB Cytochrom_B_N PF00033.14 CDJ62987.1 - 0.0077 15.6 1.2 0.0077 15.6 0.8 2.1 1 1 1 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Yip1 PF04893.12 CDJ62987.1 - 0.0081 15.6 1.7 0.0081 15.6 1.2 1.9 1 1 1 2 2 2 1 Yip1 domain DUF4131 PF13567.1 CDJ62987.1 - 0.013 14.9 6.9 0.013 14.9 4.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M50B PF13398.1 CDJ62987.1 - 0.026 13.8 8.2 0.024 14.0 4.9 1.5 1 1 0 1 1 1 0 Peptidase M50B-like DUF3328 PF11807.3 CDJ62987.1 - 0.029 14.0 0.8 5.2 6.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) Cyto_ox_2 PF02322.10 CDJ62987.1 - 0.033 13.3 3.8 0.044 12.9 2.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF1980 PF09323.5 CDJ62987.1 - 0.039 13.6 1.4 0.072 12.8 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Sarcoglycan_2 PF05510.8 CDJ62987.1 - 0.049 11.9 2.6 0.47 8.6 0.0 2.2 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon Peptidase_S49_N PF08496.5 CDJ62987.1 - 0.053 13.3 7.7 4 7.2 0.0 3.0 3 0 0 3 3 3 0 Peptidase family S49 N-terminal 7tm_1 PF00001.16 CDJ62987.1 - 0.068 12.2 4.6 0.13 11.4 0.0 2.2 1 1 1 2 2 1 0 7 transmembrane receptor (rhodopsin family) DUF3899 PF13038.1 CDJ62987.1 - 0.17 12.0 0.3 0.17 12.0 0.2 3.6 3 2 0 3 3 2 0 Domain of unknown function (DUF3899) Viral_Beta_CD PF04530.7 CDJ62987.1 - 0.22 11.6 6.4 0.66 10.1 0.2 2.7 2 1 1 3 3 3 0 Viral Beta C/D like family DUF912 PF06024.7 CDJ62987.1 - 0.24 11.4 12.2 5.5 7.0 0.0 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2946 PF11162.3 CDJ62987.1 - 0.28 11.3 14.4 0.65 10.2 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) PIG-P PF08510.7 CDJ62987.1 - 0.41 10.2 2.2 1.1 8.9 0.8 2.4 2 1 0 2 2 2 0 PIG-P ATP_synt_I PF03899.10 CDJ62987.1 - 0.99 9.6 11.1 0.2 11.8 3.4 2.4 2 1 0 2 2 2 0 ATP synthase I chain DUF1178 PF06676.6 CDJ62987.1 - 1.4 9.1 0.1 1.4 9.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) Zn_peptidase PF04228.8 CDJ62987.1 - 2.4 7.2 13.8 2.5 7.2 1.6 3.0 2 1 1 3 3 3 0 Putative neutral zinc metallopeptidase FA_desaturase PF00487.19 CDJ62987.1 - 3.4 7.0 6.9 8.3 5.7 4.8 1.8 1 1 0 1 1 1 0 Fatty acid desaturase Scs3p PF10261.4 CDJ62987.1 - 4.7 6.1 7.6 72 2.2 5.5 2.4 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF4064 PF13273.1 CDJ62987.1 - 5.3 7.1 9.1 4.4 7.4 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) LMBR1 PF04791.11 CDJ62988.1 - 6.7 5.1 9.4 8.1 4.9 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CytochromB561_N PF09786.4 CDJ62988.1 - 7.8 4.8 26.3 8.9 4.6 18.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hid1 PF12722.2 CDJ62988.1 - 8.4 3.9 23.4 9.2 3.7 16.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pyr_redox_2 PF07992.9 CDJ62989.1 - 3.7e-24 85.7 0.0 3.2e-22 79.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDJ62989.1 - 3e-16 59.5 0.8 8e-14 51.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDJ62989.1 - 1.1e-06 28.8 0.9 6.9e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SPX PF03105.14 CDJ62989.1 - 8.6e-06 25.7 4.8 1.3e-05 25.1 3.3 1.1 1 0 0 1 1 1 1 SPX domain K_oxygenase PF13434.1 CDJ62989.1 - 2e-05 23.6 2.9 0.00058 18.8 1.3 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CDJ62989.1 - 0.00054 18.5 3.1 0.015 13.7 0.2 2.3 2 0 0 2 2 2 1 HI0933-like protein Corona_nucleoca PF00937.13 CDJ62989.1 - 0.0063 15.5 29.2 0.011 14.7 20.2 1.3 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein FAD_oxidored PF12831.2 CDJ62989.1 - 0.0094 15.0 1.6 0.0094 15.0 1.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Spt20 PF12090.3 CDJ62989.1 - 0.01 15.1 6.0 0.01 15.1 4.1 2.0 2 0 0 2 2 2 0 Spt20 family FAD_binding_2 PF00890.19 CDJ62989.1 - 0.019 13.8 0.8 0.019 13.8 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 CDJ62989.1 - 0.019 13.8 0.0 0.019 13.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A SAGA-Tad1 PF12767.2 CDJ62989.1 - 0.02 14.5 13.8 0.036 13.7 9.5 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SprA-related PF12118.3 CDJ62989.1 - 0.035 13.4 24.9 0.066 12.5 17.3 1.4 1 0 0 1 1 1 0 SprA-related family CDK5_activator PF03261.10 CDJ62989.1 - 0.046 13.0 10.1 0.084 12.2 7.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein LMBR1 PF04791.11 CDJ62989.1 - 0.063 11.8 1.1 0.067 11.7 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.2 CDJ62989.1 - 0.071 10.7 12.4 0.091 10.4 8.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rtf2 PF04641.7 CDJ62989.1 - 0.091 11.9 9.1 0.15 11.1 6.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Zip PF02535.17 CDJ62989.1 - 0.1 11.6 2.2 0.13 11.2 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CDJ62989.1 - 0.13 12.0 16.8 0.25 11.0 11.7 1.4 1 0 0 1 1 1 0 DDHD domain Dicty_REP PF05086.7 CDJ62989.1 - 0.15 9.8 6.4 0.19 9.4 4.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Serinc PF03348.10 CDJ62989.1 - 0.2 10.3 6.2 0.28 9.8 4.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Raftlin PF15250.1 CDJ62989.1 - 0.24 9.8 13.0 0.47 8.9 9.0 1.4 1 0 0 1 1 1 0 Raftlin Suf PF05843.9 CDJ62989.1 - 0.26 10.9 18.2 0.029 14.0 9.7 1.4 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) DUF737 PF05300.6 CDJ62989.1 - 0.29 11.0 20.3 0.54 10.1 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF4407 PF14362.1 CDJ62989.1 - 0.35 9.7 5.1 0.54 9.1 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DAO PF01266.19 CDJ62989.1 - 0.35 9.7 2.4 1 8.1 0.8 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CDJ62989.1 - 0.37 10.8 6.3 0.43 10.6 0.6 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1510 PF07423.6 CDJ62989.1 - 0.54 9.5 13.6 1 8.7 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Period_C PF12114.3 CDJ62989.1 - 0.58 9.7 28.6 1 8.9 19.8 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RIC3 PF15361.1 CDJ62989.1 - 0.66 10.1 12.2 0.26 11.5 6.5 1.7 2 0 0 2 2 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3449 PF11931.3 CDJ62989.1 - 0.8 9.1 9.2 1.5 8.3 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF2201_N PF13203.1 CDJ62989.1 - 0.83 8.7 14.5 1.4 7.9 10.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Spore_coat_CotO PF14153.1 CDJ62989.1 - 0.91 8.9 15.5 0.066 12.6 7.4 1.5 2 0 0 2 2 1 0 Spore coat protein CotO Neur_chan_memb PF02932.11 CDJ62989.1 - 0.99 9.2 7.7 1.6 8.5 5.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region THRAP3_BCLAF1 PF15440.1 CDJ62989.1 - 1.6 7.2 38.7 2.4 6.6 26.8 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Dsh_C PF12316.3 CDJ62989.1 - 1.6 8.7 25.0 3.1 7.8 17.4 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4614 PF15391.1 CDJ62989.1 - 1.8 8.2 27.0 3.3 7.4 18.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1675 PF07897.6 CDJ62989.1 - 2.1 8.1 17.3 3.5 7.4 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_S49_N PF08496.5 CDJ62989.1 - 3.1 7.5 9.6 4.4 7.0 4.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1631 PF07793.6 CDJ62989.1 - 3.6 5.6 17.1 13 3.7 9.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) DUF4613 PF15390.1 CDJ62989.1 - 3.9 5.5 11.9 5.7 4.9 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) AUX_IAA PF02309.11 CDJ62989.1 - 4.1 7.0 12.9 8.5 6.0 8.9 1.4 1 0 0 1 1 1 0 AUX/IAA family OATP PF03137.15 CDJ62989.1 - 4.3 5.2 5.5 6.4 4.6 3.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SSP160 PF06933.6 CDJ62989.1 - 5.4 4.8 14.8 7.3 4.4 10.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF605 PF04652.11 CDJ62989.1 - 6 6.1 20.5 0.28 10.5 10.4 1.5 2 0 0 2 2 1 0 Vta1 like DUF3984 PF13136.1 CDJ62989.1 - 6.1 5.9 31.1 12 5.0 20.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) SOBP PF15279.1 CDJ62989.1 - 6.2 7.1 21.8 8.9 6.5 15.1 1.4 1 1 0 1 1 1 0 Sine oculis-binding protein FLO_LFY PF01698.11 CDJ62989.1 - 8.2 5.1 12.3 12 4.5 8.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Pyr_redox_dim PF02852.17 CDJ62990.1 - 1.2e-13 51.0 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Med15 PF09606.5 CDJ62990.1 - 0.00086 17.6 4.1 0.00086 17.6 2.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Nha1_C PF08619.5 CDJ62990.1 - 0.0016 17.7 6.4 0.0018 17.6 4.4 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus CDK2AP PF09806.4 CDJ62990.1 - 0.018 15.3 12.2 0.023 14.9 8.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4603 PF15376.1 CDJ62990.1 - 0.027 11.6 6.2 0.029 11.6 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF572 PF04502.8 CDJ62990.1 - 0.11 11.7 6.1 0.15 11.2 4.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Trs65 PF12735.2 CDJ62990.1 - 0.12 11.6 9.0 0.15 11.3 6.3 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF4175 PF13779.1 CDJ62990.1 - 0.13 9.9 8.0 0.13 9.9 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FliD_N PF02465.13 CDJ62990.1 - 0.14 12.5 8.5 0.23 11.8 5.9 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Neur_chan_memb PF02932.11 CDJ62990.1 - 0.17 11.7 3.6 0.19 11.5 2.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sporozoite_P67 PF05642.6 CDJ62990.1 - 0.25 9.1 7.2 0.29 8.9 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rota_VP2 PF05087.7 CDJ62990.1 - 0.27 9.1 1.7 0.3 8.9 1.2 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein Plasmodium_Vir PF05795.6 CDJ62990.1 - 0.27 10.3 4.0 0.34 10.0 2.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2217 PF10265.4 CDJ62990.1 - 0.57 8.8 8.7 0.67 8.6 6.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Gag_p12 PF01141.13 CDJ62990.1 - 0.71 10.0 4.6 0.15 12.2 0.8 1.6 2 0 0 2 2 1 0 Gag polyprotein, inner coat protein p12 Dehydrin PF00257.14 CDJ62990.1 - 1.4 9.2 15.2 3.8 7.8 10.7 1.7 1 1 0 1 1 1 0 Dehydrin SIN1 PF05422.7 CDJ62990.1 - 1.6 7.1 9.3 2.1 6.7 6.5 1.1 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Cwf_Cwc_15 PF04889.7 CDJ62990.1 - 1.7 8.3 11.1 2.5 7.7 7.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pex16 PF08610.5 CDJ62990.1 - 1.7 7.5 6.1 2 7.3 4.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) NPR3 PF03666.8 CDJ62990.1 - 1.8 7.0 9.8 2.1 6.7 6.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Auxin_inducible PF02519.9 CDJ62990.1 - 4.2 7.4 6.7 10 6.2 0.3 2.2 2 0 0 2 2 2 0 Auxin responsive protein Pex14_N PF04695.8 CDJ62990.1 - 5.7 6.9 14.3 5.1 7.1 0.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CMV_1a PF12467.3 CDJ62990.1 - 7.8 6.8 9.6 11 6.4 6.6 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF4366 PF14283.1 CDJ62991.1 - 1.3 8.3 12.5 1.8 7.8 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3123 PF11321.3 CDJ62991.1 - 1.7 8.9 6.1 2.6 8.3 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Zea_mays_MuDR PF05928.6 CDJ62991.1 - 6.1 6.2 9.6 8.1 5.7 6.7 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Neur_chan_memb PF02932.11 CDJ62992.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.9 2 2 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region MMR_HSR1 PF01926.18 CDJ62993.1 - 9.6e-15 54.5 0.0 3.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrmE_N PF10396.4 CDJ62993.1 - 1.7e-09 37.6 0.0 5.6e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 CDJ62993.1 - 0.0033 17.7 0.7 0.0033 17.7 0.5 3.7 3 1 0 3 3 3 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE CDK2AP PF09806.4 CDJ62993.1 - 0.004 17.4 5.4 0.004 17.4 3.7 5.3 4 1 0 5 5 4 2 Cyclin-dependent kinase 2-associated protein Dynamin_N PF00350.18 CDJ62993.1 - 0.012 15.4 2.2 0.015 15.0 0.0 2.3 2 1 0 2 2 2 0 Dynamin family Gtr1_RagA PF04670.7 CDJ62993.1 - 0.013 14.6 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF4208 PF13907.1 CDJ62993.1 - 0.05 13.8 2.7 0.21 11.8 1.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) FeoB_N PF02421.13 CDJ62993.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 CDJ62993.1 - 0.19 12.2 0.0 0.54 10.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Bestrophin PF01062.16 CDJ62993.1 - 0.24 10.3 0.3 0.45 9.4 0.2 1.4 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF3446 PF11928.3 CDJ62993.1 - 0.67 10.1 35.2 3.7 7.7 5.3 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) YjeF_N PF03853.10 CDJ62996.1 - 0.002 17.7 0.0 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus 3HCDH PF00725.17 CDJ62996.1 - 0.088 13.2 0.0 0.098 13.0 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MOZART2 PF12926.2 CDJ62996.1 - 0.11 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated YjeF_N PF03853.10 CDJ62997.1 - 3.7e-24 85.2 0.1 1.4e-23 83.3 0.1 1.7 1 1 0 1 1 1 1 YjeF-related protein N-terminus DUF2844 PF11005.3 CDJ62997.1 - 0.00019 21.2 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2844) Shadoo PF14999.1 CDJ62997.1 - 0.18 11.6 7.5 0.29 10.9 5.2 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Spore_coat_CotO PF14153.1 CDJ62998.1 - 3.6e-08 33.0 0.8 3.6e-08 33.0 0.6 1.1 1 0 0 1 1 1 1 Spore coat protein CotO tRNA-synt_2d PF01409.15 CDJ62998.1 - 1.4e-05 24.4 0.0 0.00014 21.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) Ycf1 PF05758.7 CDJ62998.1 - 0.0046 14.7 3.5 0.0054 14.5 2.4 1.0 1 0 0 1 1 1 1 Ycf1 DUF2407_C PF13373.1 CDJ62998.1 - 0.0064 16.4 5.0 0.012 15.4 3.5 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain SAGA-Tad1 PF12767.2 CDJ62998.1 - 0.016 14.9 13.9 0.025 14.2 9.6 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit HlyD_2 PF12700.2 CDJ62998.1 - 0.11 11.5 5.6 0.14 11.2 3.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein LMBR1 PF04791.11 CDJ62998.1 - 0.18 10.3 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Suf PF05843.9 CDJ62998.1 - 0.29 10.8 19.1 0.5 10.0 13.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM60A PF15396.1 CDJ62998.1 - 0.5 10.0 10.2 0.71 9.5 7.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FliP PF00813.15 CDJ62998.1 - 1.8 8.2 4.8 3 7.5 3.3 1.3 1 0 0 1 1 1 0 FliP family DUF755 PF05501.6 CDJ62999.1 - 0.023 14.7 36.2 0.023 14.7 25.1 5.4 3 2 2 5 5 5 0 Domain of unknown function (DUF755) BSP_II PF05432.6 CDJ62999.1 - 2 7.6 15.5 1.5 8.0 6.2 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) LRR_4 PF12799.2 CDJ63003.1 - 1.7e-09 37.0 1.7 0.0053 16.3 0.0 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CDJ63003.1 - 1.2e-05 24.9 0.0 0.0027 17.3 0.0 2.4 2 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 CDJ63003.1 - 0.0011 18.6 5.7 0.46 10.2 0.1 3.4 2 2 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CDJ63003.1 - 0.016 15.2 7.0 0.56 10.6 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 CDJ63003.1 - 0.21 11.7 3.7 2.1 8.6 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat SR-25 PF10500.4 CDJ63003.1 - 0.58 9.5 10.7 1.1 8.7 7.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nop14 PF04147.7 CDJ63003.1 - 9.4 4.0 11.5 11 3.8 7.9 1.1 1 0 0 1 1 1 0 Nop14-like family Arf PF00025.16 CDJ63004.1 - 2.5e-20 72.4 0.1 1.8e-18 66.4 0.0 2.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CDJ63004.1 - 8.1e-07 29.5 0.0 8.1e-07 29.5 0.0 3.2 3 1 1 4 4 4 1 Miro-like protein SRPRB PF09439.5 CDJ63004.1 - 7.4e-06 25.2 1.4 0.00022 20.5 0.9 2.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CDJ63004.1 - 7.8e-06 25.3 0.2 2.8e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 Ras family G-alpha PF00503.15 CDJ63004.1 - 0.0057 15.3 1.1 0.0057 15.3 0.8 5.3 2 2 1 3 3 3 2 G-protein alpha subunit FimP PF09766.4 CDJ63004.1 - 0.069 12.2 25.4 0.21 10.5 5.0 2.4 2 0 0 2 2 2 0 Fms-interacting protein AAA_25 PF13481.1 CDJ63004.1 - 0.1 11.9 0.1 0.1 11.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CDJ63004.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 CDJ63004.1 - 0.19 11.2 0.0 0.19 11.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain zf-DHHC PF01529.15 CDJ63004.1 - 0.84 9.0 4.6 6.9 6.0 0.1 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase Pantoate_ligase PF02569.10 CDJ63006.1 - 1.1e-38 132.5 0.0 6.7e-30 103.7 0.0 2.5 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase Acetyltransf_1 PF00583.19 CDJ63006.1 - 0.0012 18.8 0.0 0.0038 17.2 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CDJ63006.1 - 0.0017 18.4 0.2 0.0044 17.1 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDJ63006.1 - 0.0038 17.0 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 CDJ63006.1 - 0.0042 17.2 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4131 PF13567.1 CDJ63006.1 - 0.023 14.1 0.2 0.023 14.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Acetyltransf_13 PF13880.1 CDJ63006.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Spt20 PF12090.3 CDJ63006.1 - 0.1 11.9 1.7 4.8 6.4 0.2 2.2 2 0 0 2 2 2 0 Spt20 family SF-assemblin PF06705.6 CDJ63008.1 - 1.2e-20 73.7 15.2 2.5e-12 46.4 6.1 2.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin DUF3584 PF12128.3 CDJ63008.1 - 0.69 7.1 15.9 0.88 6.8 11.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LUC7 PF03194.10 CDJ63008.1 - 0.8 9.1 9.8 0.94 8.9 0.4 2.2 1 1 1 2 2 2 0 LUC7 N_terminus IncA PF04156.9 CDJ63008.1 - 1.9 8.0 16.2 5.1 6.6 1.7 2.7 1 1 2 3 3 3 0 IncA protein Fib_alpha PF08702.5 CDJ63008.1 - 2 8.5 5.2 41 4.2 1.0 2.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family BCDHK_Adom3 PF10436.4 CDJ63009.1 - 0.014 14.8 0.0 0.043 13.3 0.0 1.9 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DSPc PF00782.15 CDJ63009.1 - 0.084 12.4 1.4 0.79 9.3 0.1 2.6 1 1 2 3 3 3 0 Dual specificity phosphatase, catalytic domain TPR_2 PF07719.12 CDJ63009.1 - 0.14 12.1 0.5 30 4.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3166 PF11365.3 CDJ63009.1 - 0.22 11.9 14.4 4 7.9 1.7 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3166) DUF4162 PF13732.1 CDJ63009.1 - 0.25 11.8 5.0 1.9 9.0 1.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) Prefoldin_3 PF13758.1 CDJ63009.1 - 1.1 9.0 7.9 1.6 8.5 1.6 2.9 1 1 0 2 2 2 0 Prefoldin subunit DUF904 PF06005.7 CDJ63009.1 - 1.6 9.0 20.1 23 5.3 8.0 3.7 2 2 0 2 2 2 0 Protein of unknown function (DUF904) Sec20 PF03908.8 CDJ63009.1 - 3.5 7.4 8.9 0.54 9.9 0.6 3.2 2 2 1 3 3 3 0 Sec20 APG6 PF04111.7 CDJ63009.1 - 3.5 6.5 23.2 0.48 9.4 5.0 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 CDJ63009.1 - 5.6 6.5 21.7 2.4 7.7 0.5 4.4 3 1 1 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CDJ63010.1 - 0.083 12.6 16.3 0.078 12.7 8.0 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 CDJ63010.1 - 0.19 11.4 5.9 0.25 11.1 4.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Snapin_Pallidin PF14712.1 CDJ63010.1 - 0.5 10.7 5.2 0.74 10.1 3.2 1.7 1 1 0 1 1 1 0 Snapin/Pallidin DUF2036 PF09724.4 CDJ63010.1 - 0.53 9.3 4.9 0.55 9.3 3.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) AMP-binding_C_2 PF14535.1 CDJ63010.1 - 0.61 10.1 4.3 14 5.7 3.0 2.0 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain TMF_TATA_bd PF12325.3 CDJ63010.1 - 1.3 8.8 10.8 0.54 9.9 2.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Tup_N PF08581.5 CDJ63010.1 - 4.7 7.4 8.6 5.7 7.2 3.9 2.5 1 1 1 2 2 2 0 Tup N-terminal DUF3450 PF11932.3 CDJ63011.1 - 0.22 10.7 25.6 0.022 14.0 6.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.3 CDJ63011.1 - 0.81 9.4 20.6 0.076 12.7 4.9 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 CDJ63011.1 - 1.4 9.3 10.2 2.5 8.4 2.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Rho_Binding PF08912.6 CDJ63011.1 - 2.2 8.6 14.9 6.7 7.0 2.4 2.7 2 0 0 2 2 2 0 Rho Binding TMF_DNA_bd PF12329.3 CDJ63011.1 - 2.5 7.9 21.3 0.55 10.0 5.5 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CDJ63011.1 - 3.3 7.2 28.5 0.12 11.9 5.3 2.9 3 0 0 3 3 3 0 IncA protein zf-C2H2 PF00096.21 CDJ63014.1 - 0.00019 21.5 1.1 0.00038 20.6 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDJ63014.1 - 0.023 15.0 0.5 0.051 13.9 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger XPA_N PF01286.13 CDJ63014.1 - 0.054 13.1 0.1 0.091 12.4 0.1 1.2 1 0 0 1 1 1 0 XPA protein N-terminal zf-C2HC_2 PF13913.1 CDJ63014.1 - 0.092 12.4 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type AAA_23 PF13476.1 CDJ63014.1 - 0.13 12.6 3.8 0.21 11.9 2.7 1.5 1 1 0 1 1 1 0 AAA domain zf-C2H2_jaz PF12171.3 CDJ63014.1 - 0.15 12.2 1.6 0.44 10.7 1.1 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3138 PF11336.3 CDJ63014.1 - 1.5 6.9 8.9 2.5 6.1 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) zf-CCHC PF00098.18 CDJ63016.1 - 0.0005 19.8 2.6 0.00092 19.0 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ63016.1 - 0.062 12.9 0.5 0.092 12.4 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 CDJ63016.1 - 2.2 7.8 11.2 0.085 12.3 3.3 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger GCC2_GCC3 PF07699.8 CDJ63019.1 - 0.0099 15.4 25.3 0.011 15.3 5.9 4.0 2 1 1 3 3 3 3 GCC2 and GCC3 HrcA_DNA-bdg PF03444.10 CDJ63022.1 - 1 8.8 2.3 22 4.5 0.0 3.5 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding GCC2_GCC3 PF07699.8 CDJ63022.1 - 2.2 7.9 159.5 0.042 13.4 1.6 16.7 6 5 10 16 16 16 0 GCC2 and GCC3 GCC2_GCC3 PF07699.8 CDJ63023.1 - 4.1 7.0 21.4 0.083 12.4 2.0 4.0 3 1 0 3 3 3 0 GCC2 and GCC3 DUF2888 PF11135.3 CDJ63024.1 - 0.0027 17.4 0.0 0.034 13.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2888) DUF104 PF01954.11 CDJ63024.1 - 0.19 11.7 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF104 HAUS6_N PF14661.1 CDJ63025.1 - 0.71 9.1 5.4 0.87 8.8 3.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SlyX PF04102.7 CDJ63026.1 - 0.002 18.4 0.7 0.002 18.4 0.5 12.9 5 2 5 11 11 11 3 SlyX EF-hand_7 PF13499.1 CDJ63027.1 - 1.4e-16 60.3 0.0 6.3e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDJ63027.1 - 1.8e-16 58.1 0.4 1.4e-07 30.3 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CDJ63027.1 - 2.4e-15 54.9 3.4 6.1e-07 28.7 0.2 3.5 3 1 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.1 CDJ63027.1 - 1.3e-12 47.3 0.0 6e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CDJ63027.1 - 2.9e-11 42.7 2.1 3.9e-05 23.1 0.1 4.0 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CDJ63027.1 - 8.8e-07 28.0 0.8 3e-05 23.1 0.3 2.9 3 0 0 3 3 3 1 EF hand DUF533 PF04391.7 CDJ63027.1 - 0.056 12.8 0.0 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Peptidase_S9 PF00326.16 CDJ63028.1 - 7.1e-30 103.8 0.0 3.8e-21 75.2 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDJ63028.1 - 8.7e-06 25.5 2.2 0.00013 21.7 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ63028.1 - 0.018 14.6 0.1 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CDJ63028.1 - 0.037 13.4 0.0 0.037 13.4 0.0 4.2 2 2 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) BRICHOS PF04089.9 CDJ63028.1 - 0.04 13.7 2.0 0.12 12.2 1.4 1.8 1 0 0 1 1 1 0 BRICHOS domain Herpes_UL87 PF03043.9 CDJ63028.1 - 3.4 5.9 8.3 7.9 4.7 5.8 1.5 1 0 0 1 1 1 0 Herpesvirus UL87 family Myosin_head PF00063.16 CDJ63030.1 - 8.7e-159 529.7 0.1 1.5e-158 528.9 0.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) OmpH PF03938.9 CDJ63031.1 - 0.011 15.6 0.0 0.011 15.6 0.0 13.4 9 4 0 9 9 9 0 Outer membrane protein (OmpH-like) UAA PF08449.6 CDJ63031.1 - 0.23 10.3 0.1 0.51 9.2 0.1 1.5 1 0 0 1 1 1 0 UAA transporter family ETRAMP PF09716.5 CDJ63031.1 - 1.9 8.4 0.0 1.9 8.4 0.0 7.4 10 0 0 10 10 10 0 Malarial early transcribed membrane protein (ETRAMP) ICMT PF04140.9 CDJ63032.1 - 8.5e-22 77.1 0.5 8.5e-22 77.1 0.3 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CDJ63032.1 - 6.6e-11 42.2 0.6 1.9e-10 40.7 0.4 1.9 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 CDJ63032.1 - 0.00042 19.6 1.6 0.00042 19.6 1.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 CDJ63032.1 - 0.0024 16.4 2.3 0.0041 15.7 1.6 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3446 PF11928.3 CDJ63032.1 - 0.0091 16.1 9.6 0.024 14.8 6.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) Siva PF05458.7 CDJ63032.1 - 0.025 14.1 0.8 0.054 13.0 0.6 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) CDK2AP PF09806.4 CDJ63032.1 - 0.13 12.4 3.5 0.33 11.1 0.1 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Lysis_S PF04971.7 CDJ63032.1 - 0.29 10.8 2.7 0.49 10.1 0.2 2.7 3 0 0 3 3 3 0 Lysis protein S X PF00739.14 CDJ63032.1 - 1.2 9.0 6.8 19 5.1 2.4 2.3 2 0 0 2 2 2 0 Trans-activation protein X DUF515 PF04415.7 CDJ63032.1 - 1.8 6.7 3.8 2.5 6.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF508 PF04370.7 CDJ63032.1 - 6.9 6.2 8.3 13 5.3 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Ribosomal_60s PF00428.14 CDJ63032.1 - 6.9 7.1 11.4 0.25 11.7 3.6 1.8 2 0 0 2 2 1 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 CDJ63032.1 - 8.1 7.0 14.0 2.1 8.9 0.9 2.4 2 0 0 2 2 2 0 Chorion family 2 PCI PF01399.22 CDJ63037.1 - 3.4e-09 36.9 0.0 1.2e-08 35.1 0.0 2.1 1 0 0 1 1 1 1 PCI domain Suf PF05843.9 CDJ63038.1 - 0.0014 18.4 0.4 0.002 17.9 0.3 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDJ63038.1 - 0.023 14.7 3.9 0.036 14.1 2.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kei1 PF08552.6 CDJ63038.1 - 0.3 10.7 1.1 0.48 10.0 0.8 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Med15 PF09606.5 CDJ63038.1 - 2.1 6.4 32.3 3.1 5.8 22.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 CDJ63038.1 - 3.4 7.4 11.2 5.5 6.7 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SNAP PF14938.1 CDJ63039.1 - 0.15 11.2 14.1 0.18 10.9 9.4 1.4 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 CDJ63039.1 - 4.6 6.9 11.6 0.37 10.4 3.7 2.4 2 0 0 2 2 2 0 TPR repeat Baculo_PP31 PF05311.6 CDJ63040.1 - 0.014 14.6 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pkinase PF00069.20 CDJ63041.1 - 1.9e-18 66.5 0.0 3.6e-18 65.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDJ63041.1 - 1.5e-09 37.2 0.1 3e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDJ63041.1 - 6e-09 35.3 0.0 1.5e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDJ63041.1 - 0.0078 15.9 0.3 0.0078 15.9 0.2 3.5 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kdo PF06293.9 CDJ63041.1 - 0.013 14.6 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDJ63041.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 CDJ63042.1 - 1.4e-05 24.3 0.0 2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDJ63042.1 - 6e-05 22.3 0.0 9.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDJ63042.1 - 0.0056 15.6 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pro_isomerase PF00160.16 CDJ63043.1 - 3.3e-39 134.5 0.0 3.8e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Solute_trans_a PF03619.11 CDJ63045.1 - 0.0024 17.2 0.2 0.0058 15.9 0.1 1.6 2 0 0 2 2 2 1 Organic solute transporter Ostalpha Kinase-like PF14531.1 CDJ63046.1 - 2.5e-06 26.6 0.0 4.3e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDJ63046.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDJ63047.1 - 7.3e-07 28.4 0.0 2.1e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDJ63047.1 - 0.00094 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIR_2 PF13676.1 CDJ63047.1 - 0.042 14.0 0.1 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 TIR domain Kinase-like PF14531.1 CDJ63048.1 - 9.9e-05 21.4 0.0 0.00018 20.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDJ63048.1 - 0.00063 18.9 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63048.1 - 0.0049 15.9 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PP28 PF10252.4 CDJ63049.1 - 0.065 13.2 8.7 0.083 12.9 6.1 1.3 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Seryl_tRNA_N PF02403.17 CDJ63049.1 - 0.36 10.8 7.7 0.44 10.5 5.4 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_B PF00430.13 CDJ63049.1 - 1 9.1 8.0 1.4 8.7 5.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Dsh_C PF12316.3 CDJ63049.1 - 4.7 7.2 7.0 5.6 7.0 4.8 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal UCH PF00443.24 CDJ63051.1 - 8.3e-26 90.6 0.0 9e-25 87.2 0.0 2.8 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase Acyltransferase PF01553.16 CDJ63053.1 - 2e-10 40.2 0.0 3.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Arm PF00514.18 CDJ63054.1 - 0.0046 16.7 0.6 20 5.2 0.0 3.8 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF2999 PF11212.3 CDJ63054.1 - 0.037 14.0 0.8 0.3 11.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) CTNNBL PF08216.6 CDJ63054.1 - 0.054 13.0 0.2 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Totivirus_coat PF05518.6 CDJ63054.1 - 0.99 7.1 13.6 1.6 6.4 9.4 1.3 1 0 0 1 1 1 0 Totivirus coat protein DUF45 PF01863.12 CDJ63054.1 - 6.9 6.3 13.2 0.38 10.5 1.7 2.9 2 1 0 3 3 3 0 Protein of unknown function DUF45 Fumerase PF05681.9 CDJ63055.1 - 7.5e-88 294.1 0.0 9.6e-88 293.7 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 CDJ63055.1 - 2.1e-78 262.1 0.0 3.3e-78 261.5 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus PAT1 PF09770.4 CDJ63056.1 - 0.3 9.2 14.6 0.35 9.0 10.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IQ PF00612.22 CDJ63057.1 - 0.0029 17.0 1.0 0.0029 17.0 0.7 3.5 3 0 0 3 3 3 2 IQ calmodulin-binding motif SNF2_N PF00176.18 CDJ63059.1 - 2.3e-24 85.7 0.1 1.6e-17 63.3 0.0 2.9 3 0 0 3 3 3 2 SNF2 family N-terminal domain Glycos_transf_4 PF00953.16 CDJ63061.1 - 5e-20 71.9 13.4 1.9e-12 47.2 0.8 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 4 DUF3267 PF11667.3 CDJ63061.1 - 2.9 8.1 9.0 0.78 9.9 1.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3267) Ribosomal_60s PF00428.14 CDJ63061.1 - 9.4 6.7 10.5 7.7 6.9 1.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fer2_3 PF13085.1 CDJ63062.1 - 1.3e-30 105.4 0.0 2.3e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CDJ63062.1 - 2.5e-10 40.5 4.6 2.5e-10 40.5 3.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CDJ63062.1 - 7.3e-08 32.3 4.0 7.3e-08 32.3 2.8 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CDJ63062.1 - 3.2e-05 24.2 1.2 3.2e-05 24.2 0.8 2.9 2 2 2 4 4 4 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CDJ63062.1 - 0.00042 20.5 6.0 0.067 13.4 0.1 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CDJ63062.1 - 0.0022 17.7 4.5 0.0022 17.7 3.1 2.8 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CDJ63062.1 - 0.0028 17.9 3.8 0.0028 17.9 2.6 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CDJ63062.1 - 0.0032 17.1 4.6 0.035 13.8 0.9 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 CDJ63062.1 - 3.3 8.3 7.8 4.4 7.9 0.1 3.0 4 0 0 4 4 4 0 4Fe-4S single cluster domain Ribosomal_L5_C PF00673.16 CDJ63063.1 - 4.8e-24 83.9 0.0 7e-24 83.3 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CDJ63063.1 - 5.2e-19 67.7 0.3 2.7e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Inhibitor_I68 PF10468.4 CDJ63066.1 - 0.11 12.6 1.2 0.27 11.4 0.8 1.6 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 YSIRK_signal PF04650.12 CDJ63066.1 - 2.2 7.8 9.6 2.5 7.7 2.5 2.4 2 0 0 2 2 2 0 YSIRK type signal peptide ADH_zinc_N PF00107.21 CDJ63067.1 - 5.9e-23 80.8 0.0 8.6e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDJ63067.1 - 5.3e-17 61.5 2.5 5.3e-17 61.5 1.7 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain UDPG_MGDP_dh_N PF03721.9 CDJ63067.1 - 0.00032 20.1 0.1 0.00049 19.5 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 CDJ63067.1 - 0.024 14.4 1.9 2.1 8.1 1.2 2.3 1 1 1 2 2 2 0 ThiF family Pkinase PF00069.20 CDJ63068.1 - 5.7e-67 225.5 0.0 6.9e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63068.1 - 1.4e-33 116.0 0.0 1.8e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ63068.1 - 9.8e-08 31.2 0.0 4.3e-06 25.8 0.0 2.8 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 CDJ63068.1 - 3.3e-05 23.0 0.0 5.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDJ63068.1 - 0.00029 20.6 0.0 0.14 11.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Cytokin-bind PF09265.5 CDJ63068.1 - 0.019 14.1 0.0 0.05 12.7 0.0 1.6 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding YrbL-PhoP_reg PF10707.4 CDJ63068.1 - 0.021 14.1 0.1 0.095 12.0 0.0 1.9 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL RRM_1 PF00076.17 CDJ63069.1 - 3.2e-18 65.1 0.0 4.8e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63069.1 - 1.6e-13 50.3 0.0 2.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ63069.1 - 5.5e-08 32.5 0.0 8.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDJ63069.1 - 0.003 17.2 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Porin_3 PF01459.17 CDJ63074.1 - 5.3e-27 94.8 0.0 6.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Aminotran_5 PF00266.14 CDJ63076.1 - 8.9e-53 179.3 0.0 1.5e-50 172.0 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-V Dehydrin PF00257.14 CDJ63079.1 - 0.0033 17.7 0.0 1.3 9.2 0.1 2.8 2 1 0 2 2 2 2 Dehydrin Ribosomal_60s PF00428.14 CDJ63081.1 - 8.6 6.8 12.0 15 6.0 8.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein KH_2 PF07650.12 CDJ63082.1 - 2.1e-11 43.1 0.1 2.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CDJ63082.1 - 0.053 13.8 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 SR-25 PF10500.4 CDJ63083.1 - 0.23 10.8 49.9 0.023 14.1 9.8 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4266 PF14086.1 CDJ63083.1 - 8.5 6.9 14.5 4.2 7.9 2.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) AUX_IAA PF02309.11 CDJ63083.1 - 8.6 6.0 9.8 5.5 6.6 2.0 2.2 2 0 0 2 2 2 0 AUX/IAA family Sporozoite_P67 PF05642.6 CDJ63085.1 - 0.56 7.9 0.0 0.56 7.9 0.0 4.1 3 2 1 4 4 4 0 Sporozoite P67 surface antigen BNR_3 PF13859.1 CDJ63085.1 - 5.8 5.8 9.6 15 4.4 6.7 1.7 1 0 0 1 1 1 0 BNR repeat-like domain Ank_4 PF13637.1 CDJ63086.1 - 1.3e-12 47.8 2.7 4.4e-05 23.8 0.0 4.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CDJ63086.1 - 1.4e-07 31.7 14.1 0.00083 19.6 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ63086.1 - 2e-07 30.4 16.0 0.00062 19.4 0.0 5.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 CDJ63086.1 - 1e-06 28.7 17.7 0.0018 18.4 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeats (many copies) LRR_4 PF12799.2 CDJ63086.1 - 6.9e-05 22.3 12.1 0.00084 18.9 4.6 3.1 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ63086.1 - 7.4e-05 22.4 11.1 7.4e-05 22.4 4.9 2.3 2 0 0 2 2 2 1 Leucine rich repeat Med15 PF09606.5 CDJ63086.1 - 0.00011 20.6 57.7 0.00011 20.6 40.0 12.8 7 2 6 13 13 13 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ank_3 PF13606.1 CDJ63086.1 - 0.00074 19.5 5.6 1 9.8 0.1 5.2 6 0 0 6 6 6 2 Ankyrin repeat DUF617 PF04759.8 CDJ63088.1 - 0.044 13.4 0.6 0.044 13.4 0.4 2.1 3 0 0 3 3 3 0 Protein of unknown function, DUF617 Pkinase PF00069.20 CDJ63090.1 - 2.3e-16 59.7 0.1 1.7e-14 53.6 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63090.1 - 1.2e-06 27.8 0.1 2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF605 PF04652.11 CDJ63090.1 - 0.005 16.2 10.0 0.005 16.2 6.9 2.2 2 1 0 2 2 2 1 Vta1 like Spt20 PF12090.3 CDJ63090.1 - 0.0052 16.1 3.5 0.065 12.5 0.3 2.2 2 0 0 2 2 2 1 Spt20 family Kdo PF06293.9 CDJ63090.1 - 0.0091 15.0 3.6 0.0091 15.0 2.5 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cwf_Cwc_15 PF04889.7 CDJ63090.1 - 0.02 14.6 4.8 0.082 12.6 2.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BRF1 PF07741.8 CDJ63090.1 - 1.3 9.2 10.1 4.3 7.6 4.4 2.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF572 PF04502.8 CDJ63090.1 - 2.9 7.0 14.6 1 8.5 7.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) FimP PF09766.4 CDJ63090.1 - 3.1 6.7 12.6 0.67 8.9 3.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein Med15 PF09606.5 CDJ63090.1 - 3.5 5.6 38.4 0.076 11.2 9.7 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ63090.1 - 4.4 7.7 37.1 0.37 11.2 3.7 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDJ63090.1 - 6.1 4.9 30.0 2 6.5 11.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AP2 PF00847.15 CDJ63091.1 - 1.6e-07 31.3 0.8 1.6e-07 31.3 0.6 9.0 11 1 0 11 11 11 1 AP2 domain SR-25 PF10500.4 CDJ63091.1 - 0.00038 20.0 16.7 0.00038 20.0 11.6 8.2 6 2 2 8 8 8 2 Nuclear RNA-splicing-associated protein APG6 PF04111.7 CDJ63091.1 - 0.00098 18.2 56.7 0.00098 18.2 39.3 3.6 3 0 0 3 3 3 1 Autophagy protein Apg6 DUF3801 PF12687.2 CDJ63091.1 - 0.78 9.2 37.6 1.4 8.4 12.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) BAF1_ABF1 PF04684.8 CDJ63092.1 - 2.4e-05 23.3 31.8 2.8e-05 23.1 22.1 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.8 CDJ63092.1 - 0.0047 16.9 15.2 0.0056 16.7 10.6 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.4 CDJ63092.1 - 0.019 15.0 22.7 0.021 14.8 15.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_60s PF00428.14 CDJ63092.1 - 0.02 15.2 11.7 0.02 15.2 8.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABC2_membrane_2 PF12679.2 CDJ63092.1 - 0.026 13.3 1.7 0.032 13.1 1.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4175 PF13779.1 CDJ63092.1 - 0.07 10.8 32.8 0.075 10.7 22.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Apc15p PF05841.6 CDJ63092.1 - 0.092 13.4 12.9 0.13 13.0 9.0 1.2 1 0 0 1 1 1 0 Apc15p protein Mem_trans PF03547.13 CDJ63092.1 - 0.12 10.6 2.8 0.14 10.4 2.0 1.0 1 0 0 1 1 1 0 Membrane transport protein FimP PF09766.4 CDJ63092.1 - 0.13 11.3 18.7 0.15 11.0 13.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein FAM176 PF14851.1 CDJ63092.1 - 0.13 11.9 3.6 0.15 11.7 2.5 1.2 1 0 0 1 1 1 0 FAM176 family Pex16 PF08610.5 CDJ63092.1 - 0.18 10.7 11.0 0.2 10.6 7.6 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SRP-alpha_N PF04086.8 CDJ63092.1 - 0.21 10.9 15.9 0.22 10.8 11.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2217 PF10265.4 CDJ63092.1 - 0.31 9.7 10.1 0.35 9.5 7.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SAGA-Tad1 PF12767.2 CDJ63092.1 - 0.36 10.4 13.3 0.38 10.3 9.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Na_trans_assoc PF06512.8 CDJ63092.1 - 0.38 10.6 5.2 0.43 10.5 3.6 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Gag_spuma PF03276.9 CDJ63092.1 - 0.45 8.7 22.9 0.5 8.6 15.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF3347 PF11827.3 CDJ63092.1 - 0.5 10.3 13.4 0.66 9.9 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) YfhO PF09586.5 CDJ63092.1 - 0.52 8.2 6.8 0.61 8.0 4.7 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Otopetrin PF03189.8 CDJ63092.1 - 0.82 8.5 4.2 0.95 8.3 2.9 1.0 1 0 0 1 1 1 0 Otopetrin HGTP_anticodon2 PF12745.2 CDJ63092.1 - 0.86 8.6 11.2 1 8.4 7.8 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF2052 PF09747.4 CDJ63092.1 - 0.96 9.3 15.4 1 9.2 10.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-DHHC PF01529.15 CDJ63092.1 - 0.98 8.7 6.9 1.3 8.4 4.8 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Gti1_Pac2 PF09729.4 CDJ63092.1 - 1 9.2 5.8 1.2 8.9 4.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family PIH1 PF08190.7 CDJ63092.1 - 1.1 8.5 17.3 1.3 8.3 12.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Ctr PF04145.10 CDJ63092.1 - 1.3 9.0 9.0 1.8 8.6 6.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family UPF0560 PF10577.4 CDJ63092.1 - 1.6 6.9 17.7 1.6 6.8 12.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.4 CDJ63092.1 - 1.8 6.6 32.7 1.8 6.6 22.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ63092.1 - 2 6.5 43.8 2.1 6.4 30.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Het-C PF07217.6 CDJ63092.1 - 2 6.5 8.4 1.9 6.5 5.8 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3818 PF12825.2 CDJ63092.1 - 2.1 6.9 8.8 2.5 6.6 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) eIF-3_zeta PF05091.7 CDJ63092.1 - 2.1 6.8 16.8 2.1 6.8 11.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF966 PF06136.8 CDJ63092.1 - 2.2 7.6 12.3 2.4 7.5 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) OATP PF03137.15 CDJ63092.1 - 2.3 6.1 5.5 2.3 6.1 3.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Band_3_cyto PF07565.8 CDJ63092.1 - 2.3 7.6 11.7 2.6 7.4 8.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paf1 PF03985.8 CDJ63092.1 - 2.4 6.7 11.6 2.8 6.5 8.0 1.1 1 0 0 1 1 1 0 Paf1 AUX_IAA PF02309.11 CDJ63092.1 - 2.8 7.6 12.0 3 7.5 8.3 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF3675 PF12428.3 CDJ63092.1 - 3.2 8.0 14.6 0.24 11.6 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) SPX PF03105.14 CDJ63092.1 - 3.3 7.4 11.0 3.2 7.4 7.6 1.1 1 0 0 1 1 1 0 SPX domain DUF2215 PF10225.4 CDJ63092.1 - 3.4 7.0 8.5 3.8 6.8 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF3276 PF11680.3 CDJ63092.1 - 3.4 7.4 9.4 4.7 7.0 6.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3276) Neur_chan_memb PF02932.11 CDJ63092.1 - 3.6 7.3 14.6 3.8 7.3 10.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_env PF01673.13 CDJ63092.1 - 3.9 5.9 10.7 4.3 5.7 7.4 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Hid1 PF12722.2 CDJ63092.1 - 4.5 4.8 13.5 4.4 4.8 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_DNAp_acc PF04929.7 CDJ63092.1 - 4.8 6.0 9.9 5 5.9 6.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDRGK PF09756.4 CDJ63092.1 - 5.7 6.2 16.5 7.4 5.9 11.4 1.3 1 0 0 1 1 1 0 DDRGK domain Glyco_transf_15 PF01793.11 CDJ63092.1 - 6.2 5.6 9.9 7.2 5.4 6.9 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Ndc1_Nup PF09531.5 CDJ63092.1 - 6.4 5.0 10.7 6.4 5.0 7.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RBP_receptor PF14752.1 CDJ63092.1 - 7.1 4.8 8.0 8.2 4.6 5.6 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor Herpes_UL87 PF03043.9 CDJ63092.1 - 7.4 4.8 9.1 7.7 4.7 6.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4638 PF15472.1 CDJ63092.1 - 7.5 6.0 11.8 8.2 5.9 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF3260 PF11658.3 CDJ63092.1 - 7.8 4.5 10.7 8.8 4.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DNA_pol_viral_N PF00242.12 CDJ63092.1 - 8.6 5.2 14.7 8.5 5.2 10.2 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ycf1 PF05758.7 CDJ63092.1 - 9.8 3.7 10.3 9 3.8 7.2 1.0 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 CDJ63093.1 - 3.4 7.3 22.9 0.9 9.2 5.7 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Scramblase PF03803.10 CDJ63097.1 - 0.014 14.4 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Scramblase FAM92 PF06730.6 CDJ63097.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein zf-CCHC PF00098.18 CDJ63098.1 - 1.7e-06 27.6 8.8 0.00037 20.2 1.0 2.4 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.12 CDJ63098.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-DNA_Pol PF08996.5 CDJ63098.1 - 0.25 10.6 2.1 0.58 9.4 1.5 1.5 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zinc-ribbons_6 PF07191.7 CDJ63098.1 - 0.34 10.7 2.9 0.42 10.4 1.3 1.6 2 0 0 2 2 2 0 zinc-ribbons DnaJ_CXXCXGXG PF00684.14 CDJ63098.1 - 0.47 10.5 10.4 1.3 9.0 7.2 1.7 1 1 0 1 1 1 0 DnaJ central domain RVT_1 PF00078.22 CDJ63099.1 - 2.3e-12 46.7 0.0 5.7e-12 45.4 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 CDJ63100.1 - 0.083 12.9 0.1 0.53 10.4 0.1 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein EamA PF00892.15 CDJ63101.1 - 0.00061 19.8 2.6 0.00081 19.4 1.8 1.2 1 0 0 1 1 1 1 EamA-like transporter family Collagen PF01391.13 CDJ63101.1 - 0.0034 16.8 19.8 0.0034 16.8 13.7 3.0 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) UAA PF08449.6 CDJ63101.1 - 0.084 11.7 0.3 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 UAA transporter family DUF2681 PF10883.3 CDJ63101.1 - 0.1 12.8 5.0 0.22 11.7 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EmrE PF13536.1 CDJ63101.1 - 0.13 12.5 1.3 0.22 11.7 0.9 1.4 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Ribosomal_S26e PF01283.14 CDJ63101.1 - 0.37 11.0 2.7 0.55 10.4 1.9 1.2 1 0 0 1 1 1 0 Ribosomal protein S26e Ribosomal_S7 PF00177.16 CDJ63103.1 - 1.1e-41 141.8 0.8 1.3e-41 141.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e BRF1 PF07741.8 CDJ63104.1 - 0.21 11.8 8.2 0.3 11.3 5.7 1.3 1 1 0 1 1 1 0 Brf1-like TBP-binding domain eIF-3_zeta PF05091.7 CDJ63104.1 - 0.75 8.3 6.4 0.75 8.3 4.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDJ63104.1 - 6.8 4.8 21.1 7.1 4.7 14.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 CDJ63105.1 - 0.042 12.7 10.8 0.068 12.0 7.5 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BT1 PF03092.11 CDJ63106.1 - 4.8e-64 216.6 10.0 7.3e-64 216.0 6.9 1.2 1 0 0 1 1 1 1 BT1 family Pkinase PF00069.20 CDJ63107.1 - 1.2e-26 93.4 0.0 1.8e-25 89.5 0.0 2.8 4 1 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63107.1 - 5.7e-13 48.5 0.0 4.3e-12 45.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Borrelia_P83 PF05262.6 CDJ63107.1 - 0.94 7.6 9.9 1.3 7.2 6.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein 5-FTHF_cyc-lig PF01812.15 CDJ63108.1 - 6.5e-12 45.6 0.0 1.3e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family EPL1 PF10513.4 CDJ63109.1 - 9.4e-09 35.7 1.8 4.3e-08 33.5 0.0 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like TPR_11 PF13414.1 CDJ63110.1 - 1.4e-09 37.4 2.4 3.5e-05 23.3 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CDJ63110.1 - 0.0015 18.2 7.0 3.5 7.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ63110.1 - 0.0019 17.7 2.1 10 5.9 0.7 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CDJ63110.1 - 0.01 15.9 0.2 0.04 14.0 0.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CDJ63110.1 - 0.024 15.3 0.3 0.024 15.3 0.2 5.3 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ63110.1 - 0.045 13.6 7.7 2.3 8.2 1.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ63110.1 - 0.38 10.6 7.8 0.68 9.8 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C97 PF05903.9 CDJ63111.1 - 1.2e-24 86.8 0.0 2.6e-23 82.4 0.0 2.1 1 1 0 1 1 1 1 PPPDE putative peptidase domain Aldedh PF00171.17 CDJ63111.1 - 0.27 9.5 3.7 0.46 8.7 2.6 1.3 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Med15 PF09606.5 CDJ63112.1 - 2.5 6.1 75.8 0.004 15.4 44.6 2.0 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal LRR_4 PF12799.2 CDJ63113.1 - 0.21 11.2 1.1 1e+02 2.6 0.0 4.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CDJ63113.1 - 1.3 9.5 13.7 2.5 8.6 0.3 6.0 6 0 0 6 6 6 0 Leucine rich repeat MMR_HSR1 PF01926.18 CDJ63114.1 - 2.2e-10 40.4 0.1 6.1e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDJ63114.1 - 8.2e-06 25.1 1.5 0.34 10.1 0.0 3.2 2 1 1 3 3 3 3 Ferrous iron transport protein B Arf PF00025.16 CDJ63114.1 - 0.0066 15.7 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 CDJ63114.1 - 0.0079 15.3 0.0 0.016 14.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 CDJ63114.1 - 0.013 14.8 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Ras family GTP_EFTU PF00009.22 CDJ63114.1 - 0.024 14.0 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CDJ63114.1 - 0.074 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PseudoU_synth_1 PF01416.15 CDJ63120.1 - 2.6e-28 98.4 0.0 3.3e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 CDJ63120.1 - 0.038 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Pkinase PF00069.20 CDJ63122.1 - 1.5e-43 148.8 2.9 5.3e-43 147.0 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63122.1 - 1.9e-17 63.1 0.0 5.5e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase ABC2_membrane_3 PF12698.2 CDJ63123.1 - 0.12 11.4 0.0 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein gag-asp_proteas PF13975.1 CDJ63124.1 - 1.5e-06 27.8 0.0 3.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ63124.1 - 1.8e-05 25.1 0.0 3.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Proteasome PF00227.21 CDJ63125.1 - 3.7e-55 186.1 0.0 4.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDJ63125.1 - 4.3e-14 51.4 0.0 7.2e-14 50.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PcfK PF14058.1 CDJ63125.1 - 0.0028 17.7 2.3 0.0051 16.9 1.6 1.4 1 0 0 1 1 1 1 PcfK-like protein Terminase_5 PF06056.7 CDJ63125.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Carb_kinase PF01256.12 CDJ63126.1 - 1.3e-29 103.2 0.0 5.1e-18 65.2 0.0 3.6 3 0 0 3 3 3 3 Carbohydrate kinase DUF3404 PF11884.3 CDJ63126.1 - 0.096 11.5 0.7 0.19 10.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) BAF1_ABF1 PF04684.8 CDJ63126.1 - 0.85 8.3 10.0 1.3 7.7 6.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AP2 PF00847.15 CDJ63128.1 - 0.013 15.6 0.6 0.013 15.6 0.4 4.6 5 0 0 5 5 5 0 AP2 domain Pex14_N PF04695.8 CDJ63130.1 - 2.5 8.1 5.7 0.32 11.0 0.2 2.3 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_6 PF12697.2 CDJ63131.1 - 7.5e-22 78.3 3.2 2.4e-21 76.6 2.2 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ63131.1 - 3.7e-11 43.0 0.1 7.9e-10 38.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDJ63131.1 - 1.9e-09 37.4 0.0 6.5e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CDJ63131.1 - 0.00048 19.7 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 CDJ63131.1 - 0.0013 19.0 0.1 0.0042 17.3 0.1 1.8 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.7 CDJ63131.1 - 0.028 14.1 0.0 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) FimP PF09766.4 CDJ63134.1 - 6.1 5.8 31.4 0.13 11.3 8.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein ABC2_membrane PF01061.19 CDJ63136.1 - 0.00023 20.4 10.9 0.0018 17.4 6.8 2.1 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CDJ63136.1 - 0.00036 19.6 0.0 0.00073 18.6 0.0 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein Form_Nir_trans PF01226.12 CDJ63137.1 - 5.4e-71 238.4 14.6 6.1e-71 238.2 10.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter RhodobacterPufX PF11511.3 CDJ63137.1 - 2.5 7.5 6.3 5.3 6.4 1.0 3.0 2 1 1 3 3 3 0 Intrinsic membrane protein PufX FAM176 PF14851.1 CDJ63138.1 - 0.89 9.2 4.4 10 5.7 0.0 2.1 2 0 0 2 2 2 0 FAM176 family RAB3GAP2_N PF14655.1 CDJ63138.1 - 1.3 7.9 5.4 2 7.3 3.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cupin_2 PF07883.6 CDJ63139.1 - 4.2e-05 22.9 0.0 8.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CDJ63139.1 - 0.0034 16.8 0.4 0.0086 15.5 0.0 1.8 2 0 0 2 2 2 1 Cupin AraC_binding PF02311.14 CDJ63139.1 - 0.051 13.2 0.0 0.051 13.2 0.0 2.7 3 0 0 3 3 3 0 AraC-like ligand binding domain Period_C PF12114.3 CDJ63139.1 - 1.2 8.7 30.4 0.059 12.9 9.7 2.7 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Spt20 PF12090.3 CDJ63139.1 - 2.7 7.3 6.8 0.42 9.9 1.3 1.9 2 0 0 2 2 2 0 Spt20 family PH PF00169.24 CDJ63140.1 - 0.0001 22.4 0.0 0.00039 20.5 0.0 1.9 1 1 0 1 1 1 1 PH domain zf-CCCH PF00642.19 CDJ63141.1 - 0.00017 21.1 18.5 0.0024 17.5 0.9 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 CDJ63141.1 - 0.019 14.1 0.0 0.063 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain UCH PF00443.24 CDJ63142.1 - 0.21 10.6 0.2 0.21 10.6 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Pex14_N PF04695.8 CDJ63142.1 - 0.37 10.8 4.2 0.41 10.6 2.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TSA PF03249.8 CDJ63142.1 - 1.7 7.0 4.3 1.8 7.0 3.0 1.1 1 0 0 1 1 1 0 Type specific antigen LCCL PF03815.14 CDJ63143.1 - 3.5e-57 190.3 0.0 8.9e-18 64.0 0.0 3.6 2 1 1 3 3 3 3 LCCL domain SRCR PF00530.13 CDJ63143.1 - 2.1e-09 37.6 3.4 0.00094 19.4 0.6 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Rxt3 PF08642.5 CDJ63143.1 - 3.2e-07 30.6 0.0 0.00035 20.8 0.0 3.6 3 1 1 4 4 4 1 Histone deacetylation protein Rxt3 Laminin_G_3 PF13385.1 CDJ63143.1 - 9.9e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.12 CDJ63143.1 - 0.046 13.1 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Pentaxin family Ribosomal_60s PF00428.14 CDJ63143.1 - 4 7.8 22.5 0.35 11.3 2.7 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ63143.1 - 4.2 6.7 14.6 7.2 6.0 10.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PLAT PF01477.18 CDJ63144.1 - 7.7e-14 52.0 0.0 1.2e-11 44.9 0.0 2.7 3 0 0 3 3 3 1 PLAT/LH2 domain Vir_act_alpha_C PF10400.4 CDJ63144.1 - 0.019 15.2 0.7 0.66 10.3 0.0 2.8 3 0 0 3 3 3 0 Virulence activator alpha C-term FCP1_C PF09309.5 CDJ63144.1 - 0.41 9.8 6.2 0.6 9.3 4.3 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF4175 PF13779.1 CDJ63144.1 - 0.64 7.6 10.1 0.89 7.1 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.4 CDJ63144.1 - 3.2 5.8 12.4 6.1 4.9 8.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Tropomodulin PF03250.9 CDJ63145.1 - 0.055 12.9 0.1 1.4 8.3 0.0 2.8 2 1 0 2 2 2 0 Tropomodulin Hid1 PF12722.2 CDJ63145.1 - 0.84 7.2 1.5 1.3 6.6 1.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PseudoU_synth_2 PF00849.17 CDJ63146.1 - 8.2e-08 32.2 12.4 8.2e-08 32.2 8.6 3.1 2 1 0 2 2 2 1 RNA pseudouridylate synthase Med15 PF09606.5 CDJ63146.1 - 0.00013 20.4 6.7 0.00013 20.4 4.6 4.5 2 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1644 PF07800.7 CDJ63146.1 - 0.038 13.8 0.5 0.038 13.8 0.3 5.6 4 2 0 4 4 4 0 Protein of unknown function (DUF1644) YTH PF04146.10 CDJ63147.1 - 2.4e-29 101.7 0.0 4.5e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain CTC1 PF15489.1 CDJ63147.1 - 0.14 9.4 0.2 0.2 8.9 0.2 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Med15 PF09606.5 CDJ63147.1 - 2.3 6.3 40.7 0.25 9.5 2.7 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDJ63149.1 - 0.22 10.8 49.7 0.24 10.7 34.5 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal His_Phos_2 PF00328.17 CDJ63149.1 - 7.4 5.7 23.4 7.7 5.7 16.2 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) CAF-1_p150 PF11600.3 CDJ63150.1 - 0.011 15.1 54.9 0.014 14.7 38.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDJ63150.1 - 1.7 8.0 64.6 0.02 14.3 32.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 CDJ63150.1 - 2.6 6.4 55.7 3.4 6.0 38.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 CDJ63150.1 - 4.1 6.5 51.3 4.8 6.2 35.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOBP PF15279.1 CDJ63150.1 - 6 7.1 21.7 7.7 6.7 15.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Prp19_bind PF06991.6 CDJ63151.1 - 1.1e-55 188.8 40.8 3.6e-53 180.6 28.3 2.2 1 1 0 1 1 1 1 Splicing factor, Prp19-binding domain Med15 PF09606.5 CDJ63151.1 - 2.4 6.2 37.6 3.6 5.6 26.1 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HdeA PF06411.6 CDJ63152.1 - 1.5 8.8 6.3 6.6 6.7 4.4 2.2 1 0 0 1 1 1 0 HdeA/HdeB family CD20 PF04103.10 CDJ63152.1 - 1.8 8.5 4.5 35 4.2 2.9 2.5 2 0 0 2 2 2 0 CD20-like family Surface_antigen PF11054.3 CDJ63153.1 - 1e-71 241.3 0.2 1.1e-71 241.1 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ63154.1 - 1.8e-69 233.9 0.1 2.1e-69 233.7 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ63155.1 - 1.4e-68 231.0 0.4 1.5e-68 230.9 0.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ63156.1 - 9e-65 218.5 0.2 1.1e-64 218.3 0.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen MAGE_N PF12440.3 CDJ63156.1 - 0.48 10.7 6.0 0.072 13.3 1.4 1.7 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Surface_antigen PF11054.3 CDJ63157.1 - 1e-70 238.0 0.1 1.2e-70 237.8 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3154 PF11351.3 CDJ63157.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3154) Surface_antigen PF11054.3 CDJ63158.1 - 2.2e-77 259.8 1.2 2.6e-77 259.6 0.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ63159.1 - 3.4e-70 236.3 3.2 3.8e-70 236.1 2.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ63160.1 - 6.4e-74 248.5 0.3 7.2e-74 248.3 0.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ63161.1 - 1.4e-71 240.8 0.1 1.6e-71 240.6 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ63162.1 - 5.9e-69 232.2 0.4 6.9e-69 232.0 0.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ63163.1 - 5.1e-52 176.7 3.4 6.9e-43 146.8 2.5 2.6 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Abhydrolase_6 PF12697.2 CDJ63166.1 - 6.6e-26 91.5 0.7 1.1e-25 90.9 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDJ63166.1 - 2.4e-11 43.5 0.0 4.3e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ63166.1 - 7.2e-05 22.4 0.5 0.0033 17.0 0.3 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CDJ63166.1 - 0.0002 21.0 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 CDJ63166.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 CDJ63166.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DEAD PF00270.24 CDJ63167.1 - 6.4e-22 77.8 0.0 1.3e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 CDJ63167.1 - 0.034 12.9 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 CDJ63167.1 - 0.037 14.1 0.0 0.21 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.2 CDJ63168.1 - 6.5e-45 153.3 0.5 6.5e-45 153.3 0.3 1.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_7 PF12775.2 CDJ63169.1 - 2.7e-23 82.4 0.0 4.7e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDJ63169.1 - 6.8e-15 55.0 0.0 1.5e-11 44.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDJ63169.1 - 1.7e-06 28.8 0.0 0.0011 19.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CDJ63169.1 - 4.5e-06 26.8 0.0 0.031 14.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CDJ63169.1 - 8.9e-06 26.0 0.0 0.0026 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CDJ63169.1 - 1.1e-05 25.5 0.0 0.0073 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 CDJ63169.1 - 9.2e-05 22.3 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.4 CDJ63169.1 - 0.00016 21.1 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CDJ63169.1 - 0.00045 20.4 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 CDJ63169.1 - 0.00055 19.5 0.1 0.61 9.5 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 CDJ63169.1 - 0.0033 17.1 0.0 0.96 9.0 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 CDJ63169.1 - 0.0044 16.1 0.0 0.89 8.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 CDJ63169.1 - 0.0045 17.2 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 CDJ63169.1 - 0.0051 16.4 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CDJ63169.1 - 0.0061 16.1 0.1 0.31 10.5 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CDJ63169.1 - 0.0095 15.4 0.1 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 CDJ63169.1 - 0.013 14.3 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Sigma54_activat PF00158.21 CDJ63169.1 - 0.014 14.8 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain KTI12 PF08433.5 CDJ63169.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 CDJ63169.1 - 0.017 15.3 0.0 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 CDJ63169.1 - 0.018 14.7 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 CDJ63169.1 - 0.02 13.7 0.1 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 CDJ63169.1 - 0.023 15.2 0.0 3 8.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 CDJ63169.1 - 0.048 13.6 0.0 0.61 10.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 CDJ63169.1 - 0.054 13.1 0.1 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 CDJ63169.1 - 0.1 11.8 0.0 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Baculo_helicase PF04735.7 CDJ63169.1 - 0.17 9.1 0.0 0.24 8.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase AAA_6 PF12774.2 CDJ63170.1 - 2.1e-106 354.6 0.1 1.1e-61 208.3 0.0 2.1 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CDJ63170.1 - 0.00058 19.5 0.0 0.0045 16.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CDJ63170.1 - 0.0042 17.2 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CDJ63170.1 - 0.012 16.4 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDJ63170.1 - 0.027 14.2 0.3 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 CDJ63170.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIG PF01833.19 CDJ63171.1 - 1.3e-05 25.1 0.4 2.9e-05 23.9 0.3 1.7 1 1 0 1 1 1 1 IPT/TIG domain Filamin PF00630.14 CDJ63171.1 - 7.5e-05 23.2 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Blt1 PF12754.2 CDJ63173.1 - 2.4 7.6 4.9 1.5 8.3 1.5 1.7 2 0 0 2 2 2 0 Cell-cycle control medial ring component NfeD PF01957.13 CDJ63174.1 - 5.9 7.0 8.5 0.51 10.4 2.4 1.8 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Ubiq_cyt_C_chap PF03981.7 CDJ63175.1 - 4.5e-08 33.0 0.4 7.1e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 Ubiquinol-cytochrome C chaperone Med21 PF11221.3 CDJ63176.1 - 0.00024 21.0 1.1 0.00025 21.0 0.8 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Phage_GP20 PF06810.6 CDJ63176.1 - 0.0026 17.2 0.1 0.003 16.9 0.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 ERM PF00769.14 CDJ63176.1 - 0.016 14.7 1.4 0.023 14.2 1.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UPF0184 PF03670.8 CDJ63176.1 - 0.017 15.2 0.6 0.024 14.7 0.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Med4 PF10018.4 CDJ63176.1 - 0.019 14.3 0.3 0.028 13.8 0.2 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 VTC PF09359.5 CDJ63176.1 - 0.021 13.8 0.1 0.024 13.6 0.1 1.1 1 0 0 1 1 1 0 VTC domain Lipoprotein_6 PF01441.14 CDJ63176.1 - 0.021 14.6 0.5 0.027 14.3 0.3 1.1 1 0 0 1 1 1 0 Lipoprotein DUF1470 PF07336.6 CDJ63176.1 - 0.029 14.7 0.4 0.037 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) DUF342 PF03961.8 CDJ63176.1 - 0.038 12.4 0.3 0.04 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fzo_mitofusin PF04799.8 CDJ63176.1 - 0.052 12.9 0.3 0.067 12.5 0.2 1.3 1 0 0 1 1 1 0 fzo-like conserved region BLOC1_2 PF10046.4 CDJ63176.1 - 0.053 13.6 0.8 0.59 10.3 0.6 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V-SNARE PF05008.10 CDJ63176.1 - 0.054 13.6 2.3 0.087 13.0 1.6 1.3 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus ArsC PF03960.10 CDJ63176.1 - 0.058 13.4 0.3 0.24 11.4 0.1 1.8 1 1 1 2 2 2 0 ArsC family FliT PF05400.8 CDJ63176.1 - 0.069 13.5 1.7 0.11 12.9 1.2 1.3 1 0 0 1 1 1 0 Flagellar protein FliT APG6 PF04111.7 CDJ63176.1 - 0.076 12.0 1.2 0.087 11.8 0.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mitochondr_Som1 PF11093.3 CDJ63176.1 - 0.081 12.7 0.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial export protein Som1 DUF972 PF06156.8 CDJ63176.1 - 0.12 12.6 0.2 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 CDJ63176.1 - 0.13 11.9 3.3 0.18 11.5 2.0 1.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 CDJ63176.1 - 0.21 11.9 1.4 0.37 11.2 1.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TSC22 PF01166.13 CDJ63176.1 - 2.6 8.0 6.7 36 4.4 2.6 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.10 CDJ63176.1 - 6.5 6.6 7.1 1.3 8.9 1.7 2.2 1 1 1 2 2 2 0 Basic region leucine zipper MMR_HSR1 PF01926.18 CDJ63177.1 - 8.5e-14 51.4 0.0 1.7e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CDJ63177.1 - 8.1e-05 21.8 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 CDJ63177.1 - 0.00016 20.9 0.0 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 CDJ63177.1 - 0.019 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Septin NPFF PF15085.1 CDJ63177.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.1 2 0 0 2 2 2 0 Neuropeptide FF Arf PF00025.16 CDJ63177.1 - 0.049 12.8 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.18 CDJ63177.1 - 0.076 12.8 0.1 0.96 9.2 0.0 2.2 1 1 1 2 2 2 0 Dynamin family AAA_17 PF13207.1 CDJ63177.1 - 0.12 13.2 0.0 0.54 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 CDJ63177.1 - 0.3 10.1 0.0 0.49 9.4 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Actin PF00022.14 CDJ63179.1 - 1.3e-153 511.1 0.0 1.5e-153 510.9 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CDJ63179.1 - 0.14 12.6 0.0 0.46 10.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pkinase PF00069.20 CDJ63180.1 - 4.6e-50 170.1 0.0 6.4e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63180.1 - 4.2e-43 147.3 0.0 5.7e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ63180.1 - 0.017 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CDJ63180.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family AP2 PF00847.15 CDJ63182.1 - 9.2e-20 70.5 1.0 2.3e-09 37.2 0.2 2.4 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.1 CDJ63182.1 - 1.1e-15 57.4 0.2 2e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CDJ63183.1 - 1.6e-08 34.5 1.9 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 2 AP2 domain zf-CCHC PF00098.18 CDJ63184.1 - 0.0042 16.9 5.7 0.01 15.7 3.9 1.7 1 0 0 1 1 1 1 Zinc knuckle PcfJ PF14284.1 CDJ63184.1 - 0.025 14.0 0.6 0.045 13.2 0.0 1.6 2 0 0 2 2 2 0 PcfJ-like protein zf-CCHC_3 PF13917.1 CDJ63184.1 - 0.065 12.9 5.5 0.051 13.3 1.5 2.5 1 1 1 2 2 2 0 Zinc knuckle RNA_POL_M_15KD PF02150.11 CDJ63184.1 - 0.083 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-CCHC_6 PF15288.1 CDJ63184.1 - 0.086 12.5 3.7 0.23 11.1 2.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Whib PF02467.11 CDJ63184.1 - 0.11 12.7 3.6 0.22 11.8 1.7 2.1 2 0 0 2 2 2 0 Transcription factor WhiB zf-CCHC_4 PF14392.1 CDJ63184.1 - 0.29 10.8 6.4 0.049 13.3 1.1 2.1 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.27 CDJ63185.1 - 0.064 13.1 0.6 0.18 11.7 0.3 2.0 2 1 0 2 2 2 0 WD domain, G-beta repeat PQQ PF01011.16 CDJ63186.1 - 0.056 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat WD40 PF00400.27 CDJ63186.1 - 0.06 13.2 0.3 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 WD domain, G-beta repeat ABC_tran PF00005.22 CDJ63189.1 - 6.8e-12 45.8 0.1 1.5e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CDJ63189.1 - 1.1e-10 41.4 0.3 1.4e-10 41.0 0.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 CDJ63189.1 - 0.00021 21.3 0.1 0.00063 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CDJ63189.1 - 0.00028 20.3 0.0 0.00077 18.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CDJ63189.1 - 0.00077 18.6 0.1 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 CDJ63189.1 - 0.0013 18.6 0.2 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF3987 PF13148.1 CDJ63189.1 - 0.003 16.1 0.2 0.0048 15.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) AAA_25 PF13481.1 CDJ63189.1 - 0.0032 16.8 0.2 0.0056 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDJ63189.1 - 0.0037 18.0 0.0 0.008 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDJ63189.1 - 0.0045 16.7 0.1 0.028 14.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CDJ63189.1 - 0.011 15.8 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Beta-lactamase PF00144.19 CDJ63189.1 - 0.015 14.3 0.4 0.022 13.8 0.3 1.3 1 0 0 1 1 1 0 Beta-lactamase Miro PF08477.8 CDJ63189.1 - 0.016 15.7 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 CDJ63189.1 - 0.02 13.9 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Septin AAA_14 PF13173.1 CDJ63189.1 - 0.023 14.5 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CDJ63189.1 - 0.032 13.3 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.1 CDJ63189.1 - 0.034 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CDJ63189.1 - 0.041 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 CDJ63189.1 - 0.043 12.5 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 CDJ63189.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 VirE PF05272.6 CDJ63189.1 - 0.074 12.5 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Suf PF05843.9 CDJ63189.1 - 0.075 12.7 3.7 0.12 12.1 2.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NB-ARC PF00931.17 CDJ63189.1 - 0.079 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.13 CDJ63189.1 - 0.091 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 CDJ63189.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CDJ63189.1 - 0.1 11.3 0.5 0.16 10.6 0.1 1.5 1 1 0 1 1 1 0 ArgK protein MobB PF03205.9 CDJ63189.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CDJ63189.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 CDJ63189.1 - 0.11 11.1 3.6 0.29 9.7 2.5 1.6 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 CDJ63190.1 - 1.1e-13 51.6 1.5 1.6e-11 44.6 1.1 2.3 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CDJ63190.1 - 4.2e-08 32.7 0.4 5.4e-08 32.3 0.3 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Med15 PF09606.5 CDJ63190.1 - 0.0008 17.7 19.6 0.0008 17.7 13.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SbcCD_C PF13558.1 CDJ63190.1 - 0.0081 16.0 0.6 0.084 12.7 0.4 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Ycf1 PF05758.7 CDJ63190.1 - 0.029 12.0 1.1 0.026 12.2 0.8 1.0 1 0 0 1 1 1 0 Ycf1 Pex14_N PF04695.8 CDJ63190.1 - 0.14 12.2 7.8 0.22 11.5 5.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.11 CDJ63190.1 - 0.17 11.7 1.8 0.2 11.4 1.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.1 CDJ63190.1 - 0.25 8.9 27.9 0.33 8.5 19.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 CDJ63190.1 - 0.42 10.2 9.0 0.59 9.8 6.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 CDJ63190.1 - 0.42 10.4 13.0 0.63 9.8 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4011 PF13195.1 CDJ63190.1 - 0.46 10.4 4.9 0.75 9.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) DDHD PF02862.12 CDJ63190.1 - 0.86 9.3 8.5 1.2 8.8 5.9 1.2 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.8 CDJ63190.1 - 0.9 8.1 12.4 1.4 7.5 8.6 1.3 1 0 0 1 1 1 0 Paf1 FimP PF09766.4 CDJ63190.1 - 1 8.3 14.5 1.3 7.9 10.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein UPF0560 PF10577.4 CDJ63190.1 - 1.1 7.3 10.1 1.3 7.1 7.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Cellulose_synt PF03552.9 CDJ63190.1 - 1.2 7.3 2.7 1.5 6.9 1.9 1.1 1 0 0 1 1 1 0 Cellulose synthase Hid1 PF12722.2 CDJ63190.1 - 1.4 6.5 6.0 1.6 6.2 4.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.8 CDJ63190.1 - 1.6 8.1 7.3 0.67 9.4 3.1 1.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain BAF1_ABF1 PF04684.8 CDJ63190.1 - 3.1 6.5 17.8 4.3 6.0 12.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.12 CDJ63190.1 - 4.3 6.0 6.2 6.1 5.5 4.3 1.2 1 0 0 1 1 1 0 Presenilin DUF2217 PF10265.4 CDJ63191.1 - 2.2 6.9 5.6 2.3 6.8 3.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CDJ63191.1 - 8.1 4.4 10.0 7.5 4.5 6.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UDG PF03167.14 CDJ63192.1 - 1.1e-20 73.6 0.0 1.8e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF4647 PF15504.1 CDJ63192.1 - 0.21 10.4 6.8 0.28 10.0 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) TFIIA PF03153.8 CDJ63192.1 - 0.7 9.7 23.6 0.94 9.3 16.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IER PF05760.7 CDJ63192.1 - 0.74 9.6 18.2 1.2 9.0 12.6 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) Mitofilin PF09731.4 CDJ63192.1 - 0.74 8.4 23.5 1 7.9 16.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Plasmodium_Vir PF05795.6 CDJ63192.1 - 0.99 8.5 1.8 1.4 8.0 1.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MIP-T3 PF10243.4 CDJ63193.1 - 0.00036 19.1 5.8 0.00036 19.1 4.0 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 CDJ63193.1 - 0.0045 15.3 3.3 0.0055 15.0 2.3 1.2 1 0 0 1 1 1 1 Membrane transport protein Ndc1_Nup PF09531.5 CDJ63193.1 - 0.017 13.5 6.1 0.018 13.4 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.4 CDJ63193.1 - 0.02 13.1 22.1 0.024 12.9 15.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Pex16 PF08610.5 CDJ63193.1 - 0.04 12.9 2.8 0.044 12.7 1.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SAGA-Tad1 PF12767.2 CDJ63193.1 - 0.055 13.1 10.4 0.072 12.7 7.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1510 PF07423.6 CDJ63193.1 - 0.057 12.7 5.2 0.072 12.4 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SOBP PF15279.1 CDJ63193.1 - 0.057 13.8 6.3 0.06 13.7 4.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF605 PF04652.11 CDJ63193.1 - 0.071 12.4 13.6 0.092 12.1 9.4 1.1 1 0 0 1 1 1 0 Vta1 like Pneumo_att_G PF05539.6 CDJ63193.1 - 0.15 11.3 13.1 0.19 11.0 9.1 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF1501 PF07394.7 CDJ63193.1 - 0.18 10.5 7.1 0.23 10.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) KIAA1328 PF15369.1 CDJ63193.1 - 0.2 11.4 11.5 0.31 10.7 8.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Hid1 PF12722.2 CDJ63193.1 - 0.29 8.7 14.5 0.35 8.4 10.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CDJ63193.1 - 0.32 9.9 4.2 0.51 9.2 2.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2413 PF10310.4 CDJ63193.1 - 0.41 9.4 11.3 0.51 9.0 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4551 PF15087.1 CDJ63193.1 - 0.42 8.9 9.4 0.47 8.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.8 CDJ63193.1 - 0.59 9.9 10.3 0.72 9.6 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.11 CDJ63193.1 - 0.66 8.4 6.7 1.1 7.7 4.7 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4614 PF15391.1 CDJ63193.1 - 0.92 9.2 23.0 1.3 8.8 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Suf PF05843.9 CDJ63193.1 - 1.7 8.2 10.8 2.6 7.7 7.5 1.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 CDJ63193.1 - 1.8 8.4 6.1 2.4 7.9 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 CDJ63193.1 - 2.2 6.2 15.4 2.7 5.9 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 CDJ63193.1 - 3.2 6.1 12.7 4.6 5.6 8.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PAP1 PF08601.5 CDJ63193.1 - 3.7 7.1 25.3 4.7 6.7 17.6 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Band_3_cyto PF07565.8 CDJ63193.1 - 3.8 6.9 7.2 4.8 6.6 5.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AUX_IAA PF02309.11 CDJ63193.1 - 4.9 6.8 10.1 6.5 6.4 7.0 1.2 1 0 0 1 1 1 0 AUX/IAA family DNA_pol_viral_N PF00242.12 CDJ63193.1 - 5.8 5.8 25.7 7.7 5.4 17.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain HATPase_c PF02518.21 CDJ63194.1 - 7.3e-07 28.9 0.0 3.1e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_23 PF13476.1 CDJ63194.1 - 4.2 7.6 19.6 7.4 6.8 0.9 3.2 3 0 0 3 3 3 0 AAA domain Hydrolase PF00702.21 CDJ63197.1 - 8.3e-15 55.7 17.3 7e-09 36.4 0.0 4.8 5 1 0 5 5 5 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ63197.1 - 4.9e-14 52.9 0.0 2e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CDJ63197.1 - 4.4e-10 38.9 0.0 3.5e-09 36.0 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CDJ63197.1 - 0.064 13.2 0.1 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit MCM PF00493.18 CDJ63197.1 - 0.097 11.4 1.7 0.88 8.3 0.4 2.4 2 0 0 2 2 2 0 MCM2/3/5 family Hydrolase_3 PF08282.7 CDJ63197.1 - 0.2 11.1 0.1 0.55 9.7 0.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 CDJ63197.1 - 0.3 10.9 0.0 0.3 10.9 0.0 2.3 3 0 0 3 3 3 0 P5-type ATPase cation transporter EF-hand_7 PF13499.1 CDJ63198.1 - 2.2e-37 127.0 18.7 4e-11 42.8 0.4 4.4 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.27 CDJ63198.1 - 7.2e-29 96.8 16.7 1e-05 24.4 0.1 6.6 7 0 0 7 7 7 5 EF hand EF-hand_5 PF13202.1 CDJ63198.1 - 4.2e-27 92.2 15.0 7.5e-06 25.0 0.1 6.7 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.1 CDJ63198.1 - 9.3e-25 84.2 9.2 3.4e-05 23.3 0.1 6.7 5 1 1 6 6 6 5 EF-hand domain EF-hand_8 PF13833.1 CDJ63198.1 - 5.1e-16 58.0 15.4 0.015 14.8 0.4 6.0 5 1 1 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CDJ63198.1 - 1.9e-10 40.7 3.3 0.0076 16.2 0.0 3.2 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Unstab_antitox PF09720.5 CDJ63198.1 - 0.00018 21.1 1.4 0.00062 19.4 0.1 2.6 3 0 0 3 3 3 1 Putative addiction module component MotA_activ PF09114.5 CDJ63198.1 - 0.029 14.1 2.7 4.8 7.0 0.0 3.1 2 1 1 3 3 3 0 Transcription factor MotA, activation domain Toprim_2 PF13155.1 CDJ63198.1 - 0.064 13.5 2.8 4.7 7.6 0.2 3.0 1 1 2 3 3 3 0 Toprim-like EF-hand_4 PF12763.2 CDJ63198.1 - 0.085 12.5 7.5 6.2 6.6 0.6 4.2 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Daxx PF03344.10 CDJ63200.1 - 0.11 10.9 21.8 0.13 10.6 15.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CDJ63200.1 - 4.8 6.5 27.2 10 5.4 18.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDJ63200.1 - 5.6 4.5 24.7 6.7 4.2 17.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LMBR1 PF04791.11 CDJ63200.1 - 9.1 4.7 6.8 12 4.3 4.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Apolipoprotein PF01442.13 CDJ63201.1 - 5.4e-10 39.1 14.5 8.3e-10 38.5 10.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PAP2_C PF14360.1 CDJ63201.1 - 1.1e-06 28.8 13.8 8.2e-05 22.7 2.5 2.6 2 0 0 2 2 2 2 PAP2 superfamily C-terminal P12 PF12669.2 CDJ63201.1 - 0.00021 21.4 0.5 0.00021 21.4 0.4 7.0 6 2 0 6 6 6 1 Virus attachment protein p12 family PAP2 PF01569.16 CDJ63201.1 - 0.0034 17.0 3.0 0.0034 17.0 2.0 2.9 2 1 1 3 3 3 1 PAP2 superfamily AAA_13 PF13166.1 CDJ63201.1 - 0.11 10.8 4.9 0.15 10.4 3.4 1.1 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.10 CDJ63201.1 - 2.3 7.3 9.6 3.7 6.6 6.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Filament PF00038.16 CDJ63201.1 - 7.6 5.9 14.8 15 4.9 10.2 1.5 1 1 0 1 1 1 0 Intermediate filament protein AIP3 PF03915.8 CDJ63201.1 - 7.7 5.3 7.2 12 4.6 5.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 HAUS-augmin3 PF14932.1 CDJ63201.1 - 8.6 5.4 23.5 6.8 5.8 7.9 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TFIIS_C PF01096.13 CDJ63202.1 - 1.2e-07 31.2 0.1 1.2e-07 31.2 0.1 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CDJ63202.1 - 5.2e-07 29.2 8.9 1.3e-06 27.9 4.2 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.7 CDJ63202.1 - 0.0074 16.0 2.3 17 5.2 0.0 3.7 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DZR PF12773.2 CDJ63202.1 - 0.011 15.5 9.2 0.041 13.6 1.8 2.9 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.16 CDJ63202.1 - 0.038 13.8 6.1 0.83 9.5 0.4 3.2 3 1 0 3 3 3 0 IBR domain Lar_restr_allev PF14354.1 CDJ63202.1 - 0.041 14.1 4.4 0.17 12.2 0.1 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar PHD PF00628.24 CDJ63202.1 - 0.075 12.7 6.9 4.3 7.1 0.1 3.0 2 1 0 2 2 2 0 PHD-finger zf-ribbon_3 PF13248.1 CDJ63202.1 - 0.093 11.9 8.0 1.8 7.8 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain RRN7 PF11781.3 CDJ63202.1 - 0.096 12.1 3.3 0.92 9.0 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Rubredoxin PF00301.15 CDJ63202.1 - 0.13 12.1 0.5 0.13 12.1 0.3 3.4 2 1 1 3 3 3 0 Rubredoxin Zn_Tnp_IS1595 PF12760.2 CDJ63202.1 - 0.16 11.7 4.6 4.6 7.1 0.2 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CDJ63202.1 - 0.17 11.3 2.2 6.3 6.3 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn_ribbon_recom PF13408.1 CDJ63202.1 - 0.34 11.2 2.5 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2387 PF09526.5 CDJ63202.1 - 0.42 10.5 5.1 3.9 7.4 0.4 2.7 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Nudix_N_2 PF14803.1 CDJ63202.1 - 0.45 10.2 7.0 9.4 6.0 0.5 3.6 3 0 0 3 3 3 0 Nudix N-terminal DNA_ligase_ZBD PF03119.11 CDJ63202.1 - 0.66 9.7 5.9 11 5.7 0.1 3.4 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Ogr_Delta PF04606.7 CDJ63202.1 - 0.77 9.4 7.2 0.36 10.5 0.1 3.2 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-B_box PF00643.19 CDJ63202.1 - 0.81 9.6 4.0 37 4.3 2.5 2.6 2 1 0 2 2 2 0 B-box zinc finger HypA PF01155.14 CDJ63202.1 - 1.1 8.9 5.1 46 3.7 3.6 2.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 CDJ63202.1 - 1.6 8.7 7.4 3.5 7.6 0.2 3.0 2 1 1 3 3 3 0 zinc-finger zf-C4_Topoisom PF01396.14 CDJ63202.1 - 1.8 8.1 7.7 4.7 6.7 1.4 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger DUF2296 PF10058.4 CDJ63202.1 - 2.6 7.8 5.2 21 4.9 0.0 3.1 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zinc_ribbon_2 PF13240.1 CDJ63202.1 - 3.4 7.2 11.0 6.7 6.3 1.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-ISL3 PF14690.1 CDJ63202.1 - 9.7 6.3 7.6 1.8 8.6 0.1 2.7 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TraT PF05818.7 CDJ63204.1 - 0.029 13.8 4.2 0.19 11.1 3.0 1.9 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.1 CDJ63204.1 - 0.41 10.3 18.9 2.7 7.6 12.6 2.3 2 0 0 2 2 2 0 Glycine zipper Neur_chan_memb PF02932.11 CDJ63205.1 - 0.3 10.9 2.6 7.8 6.3 3.5 1.9 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 CDJ63205.1 - 2.2 7.9 19.9 5.8 6.5 13.8 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.4 CDJ63206.1 - 0.0005 19.6 17.7 0.0011 18.4 6.8 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ63206.1 - 0.0048 16.3 12.1 0.0048 16.3 8.4 2.6 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1823 PF08853.6 CDJ63206.1 - 0.017 14.8 0.1 0.041 13.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) Med15 PF09606.5 CDJ63206.1 - 0.066 11.4 56.5 0.092 10.9 39.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ63206.1 - 2.5 6.2 44.5 3.6 5.7 30.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCM PF00493.18 CDJ63209.1 - 1.5e-36 125.8 4.2 2e-36 125.4 2.9 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CDJ63209.1 - 1.2e-06 27.8 0.8 1.8e-06 27.2 0.6 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CDJ63209.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SR-25 PF10500.4 CDJ63209.1 - 1.6 8.1 11.2 2.3 7.6 7.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Brix PF04427.13 CDJ63211.1 - 1.9e-05 24.4 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Shadoo PF14999.1 CDJ63211.1 - 0.54 10.1 12.7 0.79 9.5 0.5 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF202 PF02656.10 CDJ63211.1 - 3.4 7.9 6.4 20 5.5 0.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF202) GCC2_GCC3 PF07699.8 CDJ63213.1 - 8.9e-13 47.5 42.0 9e-07 28.3 1.5 5.7 5 2 1 6 6 6 4 GCC2 and GCC3 Asp_protease_2 PF13650.1 CDJ63214.1 - 4.6e-11 43.0 0.0 8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ63214.1 - 1.1e-09 37.9 0.0 2.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ63214.1 - 8.3e-07 28.8 0.0 3.3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ63214.1 - 1.1e-06 28.6 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ63214.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Slu7 PF11708.3 CDJ63215.1 - 0.0047 16.7 4.9 0.0047 16.7 3.4 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor AP2 PF00847.15 CDJ63216.1 - 3e-07 30.4 0.3 3e-07 30.4 0.2 9.2 13 0 0 13 13 13 1 AP2 domain Metallophos PF00149.23 CDJ63217.1 - 5.7e-45 153.1 0.4 6.9e-45 152.9 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nop PF01798.13 CDJ63218.1 - 4.8e-50 168.7 0.1 1.5e-49 167.1 0.1 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CDJ63218.1 - 8.3e-23 79.9 0.0 1.4e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CDJ63218.1 - 2.8e-13 49.8 0.1 2.8e-13 49.8 0.0 2.3 3 0 0 3 3 3 1 NOP5NT (NUC127) domain EIF4E-T PF10477.4 CDJ63218.1 - 0.79 8.4 12.1 1.2 7.8 8.4 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4662 PF15578.1 CDJ63218.1 - 4.3 6.8 11.5 6.6 6.2 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Asp-B-Hydro_N PF05279.6 CDJ63218.1 - 5.1 6.8 20.3 8.4 6.1 14.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FancD2 PF14631.1 CDJ63218.1 - 6 3.8 7.8 7.6 3.4 5.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MFS_1 PF07690.11 CDJ63219.1 - 8.6e-26 90.4 35.3 8.6e-26 90.4 24.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDJ63219.1 - 8.1e-15 54.3 30.8 1.5e-14 53.4 21.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 CDJ63219.1 - 1.1e-07 30.3 19.2 0.00012 20.3 4.2 3.5 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LMBR1 PF04791.11 CDJ63220.1 - 7.5 5.0 3.7 11 4.4 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 CDJ63221.1 - 0.0049 16.4 1.0 0.0049 16.4 0.7 3.8 3 0 0 3 3 3 1 IncA protein Nuf2 PF03800.9 CDJ63222.1 - 0.093 12.7 3.4 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Nuf2 family HPS3_C PF14763.1 CDJ63223.1 - 0.081 11.8 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal zf-DHHC PF01529.15 CDJ63223.1 - 0.15 11.4 0.9 0.28 10.5 0.6 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Plasmodium_Vir PF05795.6 CDJ63223.1 - 0.84 8.7 6.3 2.2 7.3 4.4 1.8 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Zip PF02535.17 CDJ63223.1 - 6.6 5.6 5.8 13 4.6 4.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 CDJ63223.1 - 9.6 4.3 46.4 0.11 10.7 25.8 1.9 2 0 0 2 2 2 0 Transmembrane protein SPX PF03105.14 CDJ63225.1 - 0.27 10.9 2.3 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 SPX domain Neur_chan_memb PF02932.11 CDJ63225.1 - 7.6 6.3 7.2 8.9 6.1 0.1 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Thioredoxin PF00085.15 CDJ63226.1 - 1.5e-15 56.7 0.0 3.1e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin DnaJ PF00226.26 CDJ63226.1 - 3.3e-14 52.3 1.8 8.4e-14 51.0 1.3 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin_6 PF13848.1 CDJ63226.1 - 2.6e-10 40.4 0.6 1.5e-05 24.9 0.1 3.2 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDJ63226.1 - 0.0026 17.8 0.0 3.3 7.8 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like FadA PF09403.5 CDJ63227.1 - 0.027 14.5 0.6 0.041 13.9 0.4 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Neur_chan_memb PF02932.11 CDJ63228.1 - 0.93 9.3 11.5 3 7.6 8.0 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 CDJ63228.1 - 1.1 9.0 7.5 1.2 8.9 5.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDJ63228.1 - 1.2 6.6 5.7 1.1 6.8 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 CDJ63228.1 - 2.8 7.5 9.2 3.6 7.2 6.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ63228.1 - 4.7 5.3 29.8 6.1 4.9 20.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_7 PF01145.20 CDJ63229.1 - 5.5e-28 98.0 0.2 7.8e-28 97.5 0.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family PAP2 PF01569.16 CDJ63230.1 - 5.4e-20 71.3 1.2 5.4e-20 71.3 0.9 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 CDJ63230.1 - 0.055 13.7 0.1 0.055 13.7 0.1 2.5 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DDE_Tnp_1_4 PF13701.1 CDJ63230.1 - 0.094 10.8 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 DUF3357 PF11837.3 CDJ63231.1 - 0.074 12.9 3.7 0.53 10.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF2933 PF11666.3 CDJ63231.1 - 0.074 12.5 0.2 0.28 10.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) DUF2360 PF10152.4 CDJ63231.1 - 8.1 6.7 18.4 19 5.5 0.6 4.1 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein (DUF2360) Band_3_cyto PF07565.8 CDJ63233.1 - 0.0093 15.5 0.2 0.0093 15.5 0.2 8.0 4 2 1 5 5 5 1 Band 3 cytoplasmic domain SRP72 PF08492.7 CDJ63234.1 - 1.1e-09 38.5 10.3 2e-09 37.6 7.1 1.5 1 0 0 1 1 1 1 SRP72 RNA-binding domain Ribosomal_60s PF00428.14 CDJ63234.1 - 0.00059 20.1 6.6 0.00059 20.1 4.6 2.0 2 1 0 2 2 2 1 60s Acidic ribosomal protein Chorion_2 PF03964.10 CDJ63234.1 - 0.13 12.8 1.9 0.26 11.8 1.3 1.6 1 0 0 1 1 1 0 Chorion family 2 TPR_12 PF13424.1 CDJ63236.1 - 0.00025 20.9 3.4 0.00025 20.9 2.4 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat Spt20 PF12090.3 CDJ63236.1 - 0.057 12.7 18.4 0.16 11.2 4.3 3.2 3 0 0 3 3 3 0 Spt20 family TPR_2 PF07719.12 CDJ63236.1 - 0.099 12.6 19.1 1.3 9.1 0.7 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ63236.1 - 1.5 8.8 16.4 0.55 10.1 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 CDJ63236.1 - 5.3 7.5 12.8 11 6.5 0.1 5.9 6 0 0 6 6 6 0 Pentatricopeptide repeat domain TPR_16 PF13432.1 CDJ63236.1 - 7.5 7.3 0.0 7.4 7.3 0.8 7.2 4 2 3 7 7 7 0 Tetratricopeptide repeat Ribosomal_60s PF00428.14 CDJ63237.1 - 0.032 14.6 28.8 0.19 12.1 3.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein LZ_Tnp_IS66 PF13007.2 CDJ63237.1 - 1.3 9.7 9.7 2.9 8.6 1.0 2.4 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Asp_protease_2 PF13650.1 CDJ63238.1 - 6.9e-11 42.5 0.0 1.4e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ63238.1 - 3.5e-08 33.1 0.1 1.4e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ63238.1 - 1.2e-07 31.6 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CDJ63238.1 - 0.00011 22.0 0.0 0.00035 20.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ63238.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Pex14_N PF04695.8 CDJ63242.1 - 0.044 13.8 19.6 0.68 9.9 4.9 3.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOBP PF15279.1 CDJ63242.1 - 0.049 14.0 4.1 0.3 11.4 0.2 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein Clathrin PF00637.15 CDJ63242.1 - 0.14 11.7 11.8 0.13 11.8 0.4 4.0 4 1 0 4 4 4 0 Region in Clathrin and VPS DUF755 PF05501.6 CDJ63242.1 - 4.6 7.3 33.4 0.019 15.0 12.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Neur_chan_memb PF02932.11 CDJ63242.1 - 7.6 6.3 7.5 4.6 7.0 2.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_60s PF00428.14 CDJ63243.1 - 0.031 14.6 10.6 0.053 13.9 7.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF755 PF05501.6 CDJ63246.1 - 0.0036 17.3 3.5 0.0036 17.3 2.4 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF755) Ribosomal_60s PF00428.14 CDJ63246.1 - 0.025 14.9 21.2 0.18 12.2 2.5 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3446 PF11928.3 CDJ63246.1 - 4.4 7.5 14.4 0.25 11.5 2.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) DUF2863 PF11062.3 CDJ63247.1 - 0.0083 14.2 1.5 0.013 13.6 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2863) DUF1800 PF08811.6 CDJ63247.1 - 0.068 12.0 13.5 0.097 11.5 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Virul_fac_BrkB PF03631.10 CDJ63247.1 - 0.24 10.7 4.0 0.42 9.9 2.8 1.4 1 0 0 1 1 1 0 Virulence factor BrkB Med15 PF09606.5 CDJ63247.1 - 0.24 9.5 53.7 0.31 9.1 37.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Conotoxin PF02950.12 CDJ63247.1 - 1.5 9.6 16.9 4.4 8.1 4.3 2.5 2 1 0 2 2 2 0 Conotoxin Peptidase_S46 PF10459.4 CDJ63247.1 - 1.7 6.9 9.5 2 6.6 6.6 1.1 1 0 0 1 1 1 0 Peptidase S46 MRP-S31 PF15433.1 CDJ63247.1 - 1.8 7.9 14.3 2.4 7.4 9.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FimP PF09766.4 CDJ63247.1 - 5.6 5.9 19.6 1.5 7.8 5.1 2.2 2 0 0 2 2 2 0 Fms-interacting protein FlaG PF03646.10 CDJ63247.1 - 6.8 6.8 20.4 4.4 7.4 6.1 2.3 2 0 0 2 2 2 0 FlaG protein PAT1 PF09770.4 CDJ63247.1 - 7.8 4.5 50.0 9.5 4.3 34.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF755 PF05501.6 CDJ63247.1 - 7.9 6.5 31.0 0.64 10.0 6.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) IncA PF04156.9 CDJ63247.1 - 9.4 5.7 23.1 3.6 7.1 10.8 2.2 2 0 0 2 2 2 0 IncA protein Herpes_UL87 PF03043.9 CDJ63247.1 - 9.7 4.4 8.4 12 4.1 5.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family MCM PF00493.18 CDJ63248.1 - 8.6e-08 31.3 0.4 8.6e-08 31.3 0.2 2.5 4 0 0 4 4 4 1 MCM2/3/5 family Miro PF08477.8 CDJ63248.1 - 0.33 11.4 0.0 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein SR-25 PF10500.4 CDJ63249.1 - 1.3e-05 24.8 16.8 0.00013 21.5 5.4 8.5 8 1 1 9 9 9 2 Nuclear RNA-splicing-associated protein Abhydrolase_1 PF00561.15 CDJ63249.1 - 0.00011 21.7 1.0 0.00011 21.7 0.7 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold HNOBA PF07701.9 CDJ63250.1 - 1 8.5 4.6 0.24 10.5 0.1 1.8 2 0 0 2 2 2 0 Heme NO binding associated zf-RanBP PF00641.13 CDJ63251.1 - 7.8e-05 21.6 5.4 0.00021 20.2 3.8 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SR-25 PF10500.4 CDJ63251.1 - 0.0018 17.7 3.8 0.0018 17.7 2.6 7.1 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ63251.1 - 0.014 14.8 1.6 0.014 14.8 1.1 5.6 5 1 0 5 5 5 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDJ63252.1 - 0.0042 16.5 11.4 0.0042 16.5 7.9 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 CDJ63252.1 - 0.19 11.9 11.7 0.19 11.9 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) CAF-1_p150 PF11600.3 CDJ63252.1 - 0.38 10.0 7.3 0.37 10.1 5.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Acyl-thio_N PF12590.3 CDJ63252.1 - 0.42 11.0 3.1 0.43 11.0 2.2 1.1 1 0 0 1 1 1 0 Acyl-ATP thioesterase DUF2946 PF11162.3 CDJ63252.1 - 2.3 8.4 7.4 2.5 8.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Myco_19_kDa PF05481.7 CDJ63252.1 - 2.4 7.9 5.5 2.4 7.9 3.8 1.0 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Pex14_N PF04695.8 CDJ63252.1 - 4.7 7.2 7.5 4.6 7.3 5.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HMG_box PF00505.14 CDJ63253.1 - 1.1e-07 32.0 1.1 1.1e-07 32.0 0.7 2.1 1 1 1 2 2 2 1 HMG (high mobility group) box Macoilin PF09726.4 CDJ63253.1 - 2.2e-05 22.9 24.1 2.7e-05 22.6 16.7 1.2 1 0 0 1 1 1 1 Transmembrane protein HMG_box_2 PF09011.5 CDJ63253.1 - 2.4e-05 24.5 2.2 2.4e-05 24.5 1.5 2.3 1 1 1 2 2 1 1 HMG-box domain CBFD_NFYB_HMF PF00808.18 CDJ63253.1 - 0.00012 22.1 0.0 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BAF1_ABF1 PF04684.8 CDJ63253.1 - 0.0002 20.3 12.5 0.0002 20.3 8.7 3.0 2 1 1 3 3 1 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDJ63253.1 - 0.0063 14.7 23.4 0.0085 14.3 16.2 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Tom22 PF04281.8 CDJ63253.1 - 0.016 14.7 1.4 0.016 14.7 1.0 2.6 2 1 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 PAT1 PF09770.4 CDJ63253.1 - 0.19 9.9 24.7 0.23 9.6 17.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MRP-L46 PF11788.3 CDJ63253.1 - 0.21 12.2 10.2 0.45 11.1 7.1 1.6 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 APG6 PF04111.7 CDJ63253.1 - 0.35 9.8 16.4 0.59 9.1 11.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 AUX_IAA PF02309.11 CDJ63253.1 - 0.96 9.1 18.2 2 8.0 3.4 2.3 2 0 0 2 2 2 0 AUX/IAA family DDHD PF02862.12 CDJ63253.1 - 1.1 9.0 21.5 0.87 9.3 3.6 2.4 2 0 0 2 2 2 0 DDHD domain Band_3_cyto PF07565.8 CDJ63253.1 - 2.1 7.7 13.9 0.18 11.2 1.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF342 PF03961.8 CDJ63253.1 - 2.4 6.4 4.9 3.5 5.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_23 PF13476.1 CDJ63253.1 - 4.9 7.4 15.9 0.55 10.5 8.0 1.5 2 0 0 2 2 2 0 AAA domain Raftlin PF15250.1 CDJ63253.1 - 6.2 5.2 17.4 0.85 8.0 2.3 2.1 2 0 0 2 2 2 0 Raftlin Kinesin PF00225.18 CDJ63254.1 - 2.1e-38 131.9 1.4 1.5e-20 73.1 0.0 5.9 5 2 0 6 6 6 2 Kinesin motor domain RVP PF00077.15 CDJ63256.1 - 0.025 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3552 PF12072.3 CDJ63256.1 - 0.025 13.7 0.2 0.045 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Peptidase_S28 PF05577.7 CDJ63257.1 - 1e-13 50.7 5.6 1.1e-09 37.4 0.0 3.1 1 1 2 3 3 3 3 Serine carboxypeptidase S28 Med15 PF09606.5 CDJ63257.1 - 0.0042 15.3 12.9 0.0044 15.2 9.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ63257.1 - 0.0084 15.4 1.7 0.0099 15.2 1.2 1.3 1 0 0 1 1 1 1 Spt20 family Suf PF05843.9 CDJ63257.1 - 0.014 15.1 3.2 0.015 15.0 2.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF853 PF05872.7 CDJ63257.1 - 0.045 12.1 0.5 0.05 11.9 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Neur_chan_memb PF02932.11 CDJ63258.1 - 2.3e-05 24.4 21.5 0.022 14.6 0.3 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region DUF755 PF05501.6 CDJ63258.1 - 0.00019 21.4 22.5 0.00019 21.4 15.6 4.2 2 1 2 4 4 4 1 Domain of unknown function (DUF755) DUF1510 PF07423.6 CDJ63258.1 - 0.017 14.4 38.8 0.39 10.0 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3357 PF11837.3 CDJ63258.1 - 0.023 14.5 0.2 0.023 14.5 0.1 5.1 2 2 1 3 3 3 0 Domain of unknown function (DUF3357) CDK2AP PF09806.4 CDJ63259.1 - 1.6 8.9 16.4 0.31 11.2 4.5 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein UPF0560 PF10577.4 CDJ63259.1 - 4.6 5.3 15.2 0.13 10.4 2.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 SR-25 PF10500.4 CDJ63259.1 - 5.5 6.4 25.9 1.2 8.6 13.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.2 CDJ63260.1 - 0.045 11.4 9.2 0.058 11.0 6.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CDJ63260.1 - 0.36 9.7 2.7 0.65 8.9 1.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Gly-zipper_YMGG PF13441.1 CDJ63260.1 - 0.39 10.2 15.3 3.2e+02 0.9 10.6 2.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper DDHD PF02862.12 CDJ63260.1 - 1.6 8.4 14.7 3.6 7.3 8.7 2.0 2 0 0 2 2 2 0 DDHD domain Ctr PF04145.10 CDJ63260.1 - 1.8 8.5 7.7 2.7 8.0 4.0 1.9 2 0 0 2 2 2 0 Ctr copper transporter family Rick_17kDa_Anti PF05433.10 CDJ63260.1 - 1.9 8.1 11.3 0.39 10.4 3.2 2.4 1 1 1 2 2 2 0 Glycine zipper 2TM domain DUF2149 PF09919.4 CDJ63260.1 - 3.5 7.7 10.1 2.2 8.4 4.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) zf-DHHC PF01529.15 CDJ63260.1 - 3.7 6.9 9.8 1.2e+02 1.9 7.9 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Presenilin PF01080.12 CDJ63260.1 - 3.9 6.2 9.5 4.8 5.8 6.6 1.1 1 0 0 1 1 1 0 Presenilin IMCp PF12314.3 CDJ63261.1 - 3.6e-10 39.8 44.3 1.8e-07 31.1 11.2 4.0 2 1 2 4 4 4 3 Inner membrane complex protein Thioredoxin PF00085.15 CDJ63262.1 - 3.9e-29 100.3 0.0 6.2e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CDJ63262.1 - 1.9e-09 37.6 0.0 1e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CDJ63262.1 - 1.2e-05 25.2 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CDJ63262.1 - 1.7e-05 24.8 0.0 0.00012 22.1 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.1 CDJ63262.1 - 0.00043 19.8 0.0 0.00063 19.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.6 CDJ63262.1 - 0.00086 19.1 0.0 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 CDJ63262.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CDJ63262.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 CDJ63262.1 - 0.11 12.5 0.0 2.7 7.9 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.1 CDJ63262.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 CDJ63262.1 - 0.17 11.4 0.3 0.34 10.4 0.0 1.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain JAB PF01398.16 CDJ63263.1 - 4.6e-11 42.4 0.0 8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CDJ63263.1 - 2.5e-09 37.2 0.0 3.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Apolipoprotein PF01442.13 CDJ63263.1 - 0.018 14.5 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain IL3 PF02059.10 CDJ63266.1 - 0.0052 16.7 1.4 0.012 15.6 1.0 1.6 1 0 0 1 1 1 1 Interleukin-3 FemAB PF02388.11 CDJ63266.1 - 0.15 10.7 12.5 0.096 11.3 0.7 2.8 2 1 0 3 3 3 0 FemAB family SYCE1 PF15233.1 CDJ63266.1 - 0.24 11.2 29.3 0.74 9.7 9.2 2.5 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 GIDA_assoc_3 PF13932.1 CDJ63266.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.5 3 0 0 3 3 3 0 GidA associated domain 3 Gon7 PF08738.5 CDJ63266.1 - 0.5 10.3 6.9 0.8 9.7 2.7 2.9 1 1 1 2 2 2 0 Gon7 family DUF641 PF04859.7 CDJ63266.1 - 0.57 9.9 20.5 0.28 10.9 3.3 3.0 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Lebercilin PF15619.1 CDJ63266.1 - 0.73 9.2 33.8 0.06 12.7 10.9 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Snapin_Pallidin PF14712.1 CDJ63266.1 - 0.91 9.8 28.1 0.88 9.9 2.4 3.8 2 2 1 3 3 3 0 Snapin/Pallidin Baculo_p24 PF05073.7 CDJ63266.1 - 1.2 8.7 14.3 3.3 7.2 0.6 2.6 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF1664 PF07889.7 CDJ63266.1 - 1.5 8.6 15.7 2.8 7.7 1.3 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) V-ATPase_C PF03223.10 CDJ63266.1 - 1.7 7.4 10.7 0.8 8.5 5.2 1.8 1 1 1 2 2 2 0 V-ATPase subunit C Cytochrom_B562 PF07361.6 CDJ63266.1 - 1.9 8.9 9.8 2.4 8.6 1.3 2.7 1 1 0 2 2 2 0 Cytochrome b562 CDC37_N PF03234.9 CDJ63266.1 - 2 8.7 23.5 2.6 8.3 8.1 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Bacillus_HBL PF05791.6 CDJ63266.1 - 2.5 7.4 16.7 0.06 12.7 3.7 3.0 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF4226 PF10774.4 CDJ63266.1 - 3.9 7.5 11.6 0.15 12.1 1.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) FUSC PF04632.7 CDJ63266.1 - 8.9 4.6 15.2 16 3.7 10.5 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family PH PF00169.24 CDJ63267.1 - 0.0013 18.8 0.0 0.17 12.0 0.0 2.8 3 0 0 3 3 3 2 PH domain DUF3043 PF11241.3 CDJ63269.1 - 0.045 13.3 1.4 0.047 13.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Suf PF05843.9 CDJ63269.1 - 0.18 11.4 14.4 0.18 11.4 10.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ63269.1 - 0.3 10.0 9.0 0.32 10.0 6.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDJ63269.1 - 0.31 10.3 6.6 0.3 10.4 4.6 1.1 1 0 0 1 1 1 0 Spt20 family RIC3 PF15361.1 CDJ63269.1 - 0.71 10.1 12.4 0.71 10.0 8.6 1.0 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 bZIP_C PF12498.3 CDJ63269.1 - 2.3 9.4 12.4 2.4 9.4 8.6 1.1 1 0 0 1 1 1 0 Basic leucine-zipper C terminal DUF4175 PF13779.1 CDJ63269.1 - 2.7 5.5 19.7 2.7 5.5 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC27 PF09507.5 CDJ63269.1 - 3.3 6.8 11.5 3.2 6.8 8.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF605 PF04652.11 CDJ63269.1 - 3.6 6.8 22.8 3.5 6.9 15.8 1.0 1 0 0 1 1 1 0 Vta1 like Band_3_cyto PF07565.8 CDJ63269.1 - 4 6.8 6.9 4.6 6.6 4.8 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain dsDNA_bind PF01984.15 CDJ63269.1 - 7.4 6.6 16.3 8.5 6.4 11.3 1.1 1 0 0 1 1 1 0 Double-stranded DNA-binding domain ERF PF04404.7 CDJ63269.1 - 8 5.9 12.9 8.6 5.8 9.0 1.1 1 0 0 1 1 1 0 ERF superfamily BAF1_ABF1 PF04684.8 CDJ63269.1 - 9.7 4.9 24.4 10 4.8 16.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK5_activator PF03261.10 CDJ63269.1 - 9.7 5.4 7.4 9.2 5.4 5.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Zip PF02535.17 CDJ63269.1 - 9.9 5.0 6.1 10 5.0 4.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter LON PF02190.11 CDJ63270.1 - 3.4e-10 39.9 0.0 7.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_2 PF13639.1 CDJ63270.1 - 8.7e-09 35.0 9.6 8.7e-09 35.0 6.6 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CDJ63270.1 - 1.6e-07 30.8 10.3 1.6e-07 30.8 7.1 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ63270.1 - 5.7e-07 29.4 11.4 5.7e-07 29.4 7.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 CDJ63270.1 - 1.9e-06 27.7 4.1 2e-06 27.6 0.2 2.3 2 0 0 2 2 2 1 U-box domain zf-RING_5 PF14634.1 CDJ63270.1 - 5e-06 26.1 6.6 5e-06 26.1 4.5 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CDJ63270.1 - 7.8e-06 25.6 12.0 7.8e-06 25.6 8.3 2.5 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CDJ63270.1 - 1.5e-05 24.5 9.6 1.5e-05 24.5 6.7 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDJ63270.1 - 0.00028 20.5 4.5 0.00028 20.5 3.1 3.2 3 1 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 CDJ63270.1 - 0.0053 16.8 3.8 0.0053 16.8 2.6 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger Spt20 PF12090.3 CDJ63270.1 - 0.0077 15.5 11.3 0.54 9.5 1.2 3.2 3 0 0 3 3 3 3 Spt20 family DUF1053 PF06327.9 CDJ63270.1 - 0.074 13.3 7.4 0.23 11.7 0.4 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) FimP PF09766.4 CDJ63270.1 - 0.95 8.4 22.8 0.48 9.4 2.5 3.1 3 0 0 3 3 3 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDJ63270.1 - 8.1 5.3 19.3 0.98 8.3 1.3 3.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_60s PF00428.14 CDJ63271.1 - 0.0018 18.6 2.0 0.0025 18.1 1.4 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein NQRA PF05896.6 CDJ63271.1 - 0.053 12.6 3.3 0.1 11.7 1.8 1.7 1 1 1 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RNA_lig_T4_1 PF09511.5 CDJ63271.1 - 0.098 12.1 0.2 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 RNA ligase DUF2458 PF10454.4 CDJ63271.1 - 0.35 10.7 9.7 0.59 10.0 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF3678 PF12435.3 CDJ63271.1 - 0.4 10.2 5.3 1.1 8.8 3.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) HI0933_like PF03486.9 CDJ63271.1 - 0.86 7.9 3.8 1.3 7.3 2.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Spore_III_AF PF09581.5 CDJ63271.1 - 2.3 8.0 5.6 3.9 7.2 3.9 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) PAT1 PF09770.4 CDJ63271.1 - 3.3 5.8 20.0 3.3 5.8 13.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF429 PF04250.8 CDJ63271.1 - 6.6 5.9 7.1 1.2 8.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF429) NAP PF00956.13 CDJ63272.1 - 1.1e-30 106.5 0.0 1.9e-30 105.8 0.0 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) SR-25 PF10500.4 CDJ63272.1 - 0.0001 21.8 4.5 0.00014 21.3 3.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Lge1 PF11488.3 CDJ63272.1 - 0.025 14.7 2.1 0.048 13.8 1.4 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Sec3_C PF09763.4 CDJ63272.1 - 0.049 11.7 0.2 0.057 11.5 0.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 SLX9 PF15341.1 CDJ63272.1 - 0.055 13.9 0.2 0.072 13.5 0.1 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Tmemb_cc2 PF10267.4 CDJ63272.1 - 0.26 9.8 6.4 0.36 9.3 4.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Cwf_Cwc_15 PF04889.7 CDJ63272.1 - 0.38 10.4 3.0 0.55 9.9 2.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pap_E4 PF02711.9 CDJ63273.1 - 9.7 7.0 7.8 4.3 8.2 3.2 2.0 2 0 0 2 2 2 0 E4 protein RNA_pol_Rpb5_C PF01191.14 CDJ63274.1 - 2.5e-15 55.7 0.1 2.5e-15 55.7 0.1 4.0 2 1 1 3 3 3 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CDJ63274.1 - 0.0017 18.7 0.0 0.0017 18.7 0.0 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain DUF2805 PF10985.3 CDJ63274.1 - 0.68 9.9 0.0 0.68 9.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2805) PAT1 PF09770.4 CDJ63274.1 - 4.3 5.4 82.0 6 4.9 56.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDJ63275.1 - 7.3 4.6 65.4 9.3 4.2 45.3 1.0 1 0 0 1 1 1 0 Utp14 protein DUF3682 PF12446.3 CDJ63277.1 - 0.0038 17.5 20.7 0.0038 17.5 14.4 8.9 7 2 1 8 8 8 1 Protein of unknown function (DUF3682) PA14 PF07691.7 CDJ63278.1 - 8.3e-11 41.7 0.1 7.3e-10 38.6 0.0 2.2 1 1 0 1 1 1 1 PA14 domain LCCL PF03815.14 CDJ63278.1 - 1e-08 35.0 0.0 3.9e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 LCCL domain ABC_tran PF00005.22 CDJ63279.1 - 1.1e-35 122.8 4.3 4.5e-15 56.1 0.0 5.4 4 1 0 4 4 4 2 ABC transporter ABC_membrane PF00664.18 CDJ63279.1 - 9e-17 61.3 0.2 1.7e-07 30.9 0.1 3.3 2 1 1 3 3 3 2 ABC transporter transmembrane region AAA_29 PF13555.1 CDJ63279.1 - 2.2e-05 23.9 1.3 0.27 10.7 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CDJ63279.1 - 0.00017 21.6 0.0 1.5 8.7 0.0 3.3 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CDJ63279.1 - 0.00021 21.1 0.7 0.22 11.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CDJ63279.1 - 0.00049 19.6 0.1 0.18 11.2 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 CDJ63279.1 - 0.00061 19.2 8.8 0.019 14.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 CDJ63279.1 - 0.00077 18.6 1.5 1.2 8.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 CDJ63279.1 - 0.0032 16.4 3.6 4.8 5.9 0.0 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein MobB PF03205.9 CDJ63279.1 - 0.017 14.8 0.1 1.8 8.2 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CDJ63279.1 - 0.03 13.7 2.2 0.73 9.2 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Miro PF08477.8 CDJ63279.1 - 0.033 14.6 7.2 1.2 9.6 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein cobW PF02492.14 CDJ63279.1 - 0.072 12.5 1.3 9.2 5.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 CDJ63279.1 - 0.073 12.3 1.2 3.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Spt20 PF12090.3 CDJ63279.1 - 0.21 10.8 12.7 0.85 8.9 0.3 3.4 3 0 0 3 3 3 0 Spt20 family DUF87 PF01935.12 CDJ63279.1 - 0.24 11.2 8.9 2 8.1 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_22 PF13401.1 CDJ63279.1 - 0.82 9.8 5.5 4.6 7.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 CDJ63279.1 - 1.3 9.3 0.0 1.3 9.3 0.0 5.1 5 0 0 5 5 4 0 AAA domain AAA_17 PF13207.1 CDJ63279.1 - 3.4 8.5 5.1 11 6.8 0.4 2.7 2 0 0 2 2 2 0 AAA domain DUF2201_N PF13203.1 CDJ63280.1 - 4.6 6.3 35.1 5.6 6.0 24.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Ycf1 PF05758.7 CDJ63280.1 - 6.3 4.3 29.0 5.9 4.4 20.1 1.0 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 CDJ63281.1 - 0.16 11.5 0.2 0.16 11.5 0.1 2.5 1 1 1 2 2 2 0 IncA protein Herpes_UL21 PF03252.8 CDJ63281.1 - 0.34 9.3 1.3 0.51 8.7 0.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL21 DUF2562 PF10814.3 CDJ63281.1 - 1.7 8.6 5.5 1.7 8.6 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) SR-25 PF10500.4 CDJ63281.1 - 4 6.8 35.6 1.2 8.5 8.7 2.8 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein AhpC-TSA PF00578.16 CDJ63282.1 - 2.6e-33 114.3 0.0 3.5e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDJ63282.1 - 1.8e-14 53.4 0.0 2.3e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CDJ63282.1 - 1.1e-13 50.5 0.3 1.7e-13 49.9 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF1645 PF07816.6 CDJ63283.1 - 1.8 8.9 21.5 2.4 8.6 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Corona_nucleoca PF00937.13 CDJ63283.1 - 5.2 5.9 18.0 6.4 5.6 12.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Hex_IIIa PF02455.11 CDJ63283.1 - 5.6 5.5 8.8 5.9 5.4 6.1 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Ribosomal_60s PF00428.14 CDJ63284.1 - 0.061 13.7 37.0 0.1 13.0 1.9 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein HIG_1_N PF04588.8 CDJ63284.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.2 3 0 0 3 3 3 0 Hypoxia induced protein conserved region Ribosomal_60s PF00428.14 CDJ63285.1 - 0.12 12.8 33.8 0.058 13.7 4.3 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-C4H2 PF10146.4 CDJ63285.1 - 0.28 11.1 1.7 12 5.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein PAP2 PF01569.16 CDJ63286.1 - 2e-05 24.2 8.2 2e-05 24.2 5.7 2.2 2 1 1 3 3 3 1 PAP2 superfamily DUF3976 PF13121.1 CDJ63286.1 - 0.27 11.1 1.3 0.49 10.2 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3976) DUF2514 PF10721.4 CDJ63287.1 - 0.0094 15.6 8.1 0.012 15.2 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Med15 PF09606.5 CDJ63287.1 - 0.04 12.1 14.4 0.043 12.0 10.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SHR3_chaperone PF08229.6 CDJ63287.1 - 1.4 7.8 3.1 1.8 7.4 2.2 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 RRM_6 PF14259.1 CDJ63288.1 - 0.0032 17.4 0.0 0.05 13.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ63288.1 - 0.061 12.9 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 CDJ63289.1 - 0.0017 17.8 16.7 0.0017 17.8 11.6 8.9 8 2 1 9 9 9 1 Vta1 like Med15 PF09606.5 CDJ63292.1 - 0.00027 19.3 110.5 0.00037 18.8 76.6 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDJ63292.1 - 0.013 15.8 36.5 0.017 15.5 25.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 CDJ63292.1 - 0.09 11.0 96.6 0.12 10.5 66.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Parvo_coat PF00740.13 CDJ63292.1 - 0.16 10.8 36.0 0.19 10.6 25.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Hid1 PF12722.2 CDJ63292.1 - 1.2 6.6 35.4 1.7 6.2 24.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.6 CDJ63292.1 - 2.9 6.1 22.7 3.5 5.8 15.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 Serinc PF03348.10 CDJ63293.1 - 0.018 13.7 0.5 0.034 12.8 0.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) VKG_Carbox PF05090.9 CDJ63293.1 - 0.09 11.6 1.1 0.12 11.1 0.7 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Spt20 PF12090.3 CDJ63293.1 - 0.17 11.2 4.3 0.32 10.3 3.0 1.4 1 0 0 1 1 1 0 Spt20 family Herpes_UL87 PF03043.9 CDJ63293.1 - 0.76 8.0 3.4 0.93 7.8 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF788 PF05620.6 CDJ63293.1 - 1.4 8.7 4.2 0.58 9.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF788) IncA PF04156.9 CDJ63293.1 - 5.8 6.4 25.5 0.04 13.5 6.4 2.6 2 1 0 2 2 2 0 IncA protein Spt5-NGN PF03439.8 CDJ63295.1 - 5.8e-15 54.8 0.0 1.3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 CDJ63295.1 - 8.2e-10 39.1 43.6 2.2e-09 37.8 7.2 3.2 2 1 1 3 3 3 3 Spt5 transcription elongation factor, acidic N-terminal SAGA-Tad1 PF12767.2 CDJ63295.1 - 0.16 11.6 19.3 0.21 11.2 13.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Draxin PF15550.1 CDJ63295.1 - 0.45 10.1 17.5 0.58 9.7 12.1 1.2 1 0 0 1 1 1 0 Draxin SOBP PF15279.1 CDJ63295.1 - 1.1 9.5 15.2 1.4 9.1 10.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC27 PF09507.5 CDJ63295.1 - 5.5 6.0 34.2 6.7 5.8 23.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.2 CDJ63295.1 - 7.9 4.0 22.7 9.5 3.7 15.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 CDJ63296.1 - 2.6e-18 65.4 51.9 5.6e-16 57.6 26.9 4.9 3 1 1 4 4 4 3 Nop14-like family Dus PF01207.12 CDJ63297.1 - 9.3e-10 37.8 8.9 4.3e-08 32.3 6.1 2.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) RNase_Zc3h12a PF11977.3 CDJ63297.1 - 0.072 12.9 2.7 0.28 11.0 0.4 2.3 1 1 1 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_60s PF00428.14 CDJ63297.1 - 0.98 9.8 15.7 0.3 11.5 4.3 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein RAB3GAP2_N PF14655.1 CDJ63298.1 - 1.6 7.6 13.6 1.8 7.4 9.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Usp PF00582.21 CDJ63298.1 - 3.8 7.6 6.6 0.55 10.4 1.4 1.7 1 1 1 2 2 2 0 Universal stress protein family Herpes_TAF50 PF03326.8 CDJ63298.1 - 5.2 5.9 25.8 5.5 5.8 17.9 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Sugar_tr PF00083.19 CDJ63299.1 - 2.3e-47 161.5 18.5 1.5e-33 116.1 2.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDJ63299.1 - 1.8e-18 66.3 52.7 1.6e-10 40.2 16.2 4.4 4 1 0 4 4 4 4 Major Facilitator Superfamily Ycf1 PF05758.7 CDJ63299.1 - 0.019 12.7 0.2 0.019 12.7 0.1 2.1 2 0 0 2 2 2 0 Ycf1 IBV_3C PF03620.8 CDJ63299.1 - 2 8.3 5.7 3.7 7.4 0.2 2.8 3 0 0 3 3 3 0 IBV 3C protein DUF1681 PF07933.9 CDJ63299.1 - 2.5 7.6 7.8 0.06 12.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) Neur_chan_memb PF02932.11 CDJ63299.1 - 2.9 7.7 8.7 4.7 7.0 0.2 2.5 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region PUB PF09409.5 CDJ63300.1 - 2.4e-05 23.9 0.0 9.3e-05 22.1 0.0 2.0 1 0 0 1 1 1 1 PUB domain Shadoo PF14999.1 CDJ63300.1 - 0.35 10.7 14.2 0.19 11.5 7.4 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SprA-related PF12118.3 CDJ63300.1 - 6.1 6.0 72.7 4 6.6 5.0 3.3 3 0 0 3 3 3 0 SprA-related family RRM_1 PF00076.17 CDJ63302.1 - 3.2e-16 58.7 0.1 6.3e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63302.1 - 1.1e-13 50.9 0.0 3.2e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RAP1 PF07218.6 CDJ63302.1 - 7.8 4.4 14.2 10 4.0 9.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Neur_chan_memb PF02932.11 CDJ63302.1 - 8.9 6.1 18.9 0.13 12.0 3.0 2.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.17 CDJ63303.1 - 2.9e-18 65.2 0.1 4.2e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63303.1 - 4.6e-12 45.7 0.0 7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDJ63303.1 - 0.004 16.8 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 CDJ63303.1 - 0.0041 16.9 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDJ63303.1 - 0.07 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Nop16 PF09420.5 CDJ63304.1 - 6.1e-12 45.9 0.0 6.1e-12 45.9 0.0 1.6 2 0 0 2 2 2 1 Ribosome biogenesis protein Nop16 DUF755 PF05501.6 CDJ63304.1 - 0.0092 16.0 7.3 0.0092 16.0 5.1 3.6 2 1 1 3 3 3 1 Domain of unknown function (DUF755) Myb_DNA-bind_4 PF13837.1 CDJ63304.1 - 0.015 15.4 0.1 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Macro PF01661.16 CDJ63305.1 - 0.00022 21.1 0.0 0.00099 19.0 0.0 2.1 2 0 0 2 2 2 1 Macro domain AAA_23 PF13476.1 CDJ63305.1 - 9.6 6.4 11.6 1.4 9.1 2.6 2.4 2 1 0 2 2 2 0 AAA domain rve PF00665.21 CDJ63306.1 - 1e-13 51.4 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDJ63306.1 - 1.2e-13 50.4 0.0 2.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 CDJ63306.1 - 0.092 12.2 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 Integrase core domain SR-25 PF10500.4 CDJ63308.1 - 5.4 6.4 14.9 0.11 11.9 3.9 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ63309.1 - 2.1e-05 24.1 8.3 3.7e-05 23.3 3.4 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 CDJ63309.1 - 0.00051 19.2 0.2 0.21 10.6 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63309.1 - 0.0014 17.7 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pex14_N PF04695.8 CDJ63309.1 - 0.17 11.9 4.6 2 8.4 0.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3446 PF11928.3 CDJ63309.1 - 5.2 7.3 12.7 0.22 11.7 4.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) LRR_4 PF12799.2 CDJ63310.1 - 0.0041 16.6 0.7 1 9.0 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ63310.1 - 0.05 13.3 4.4 0.12 12.1 0.0 3.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 CDJ63310.1 - 0.088 12.9 5.0 54 4.3 0.0 5.7 7 0 0 7 7 7 0 Leucine Rich repeat zf-DHHC PF01529.15 CDJ63310.1 - 0.76 9.1 0.0 3 7.1 0.0 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase Cyto_ox_2 PF02322.10 CDJ63311.1 - 3.7 6.6 19.8 4.6 6.3 13.7 1.0 1 0 0 1 1 1 0 Cytochrome oxidase subunit II Spore_YhcN_YlaJ PF09580.5 CDJ63311.1 - 3.7 7.6 8.4 5.4 7.0 5.8 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Pro-rich PF15240.1 CDJ63312.1 - 8.4e-06 25.9 0.4 8.4e-06 25.9 0.3 7.0 2 1 3 5 5 5 2 Proline-rich Herpes_UL87 PF03043.9 CDJ63312.1 - 0.0023 16.3 0.0 0.014 13.8 0.0 2.2 2 1 0 2 2 2 1 Herpesvirus UL87 family SAPS PF04499.10 CDJ63312.1 - 0.95 8.0 21.5 2e+02 0.3 0.0 3.0 2 2 0 2 2 2 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 CDJ63312.1 - 5.3 5.2 5.4 1.8 6.7 1.7 1.7 2 0 0 2 2 2 0 Membrane transport protein DUF605 PF04652.11 CDJ63313.1 - 0.0012 18.3 2.2 0.0014 18.0 1.6 1.1 1 0 0 1 1 1 1 Vta1 like Dicty_REP PF05086.7 CDJ63314.1 - 0.096 10.4 1.1 0.13 9.9 0.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SR-25 PF10500.4 CDJ63314.1 - 0.17 11.3 39.6 0.52 9.7 0.3 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.6 CDJ63314.1 - 3 5.6 9.3 5.2 4.8 6.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_viral_N PF00242.12 CDJ63314.1 - 7.2 5.5 24.2 0.076 12.0 10.6 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Med3 PF11593.3 CDJ63315.1 - 0.0061 15.8 9.6 0.0061 15.8 6.7 1.9 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal SPX PF03105.14 CDJ63315.1 - 0.0095 15.7 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 SPX domain TMPIT PF07851.8 CDJ63315.1 - 0.94 8.4 4.6 1.8 7.5 3.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Lin-8 PF03353.10 CDJ63315.1 - 5.4 6.1 10.2 7.3 5.7 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cnd1_N PF12922.2 CDJ63315.1 - 8.7 5.9 11.7 26 4.4 8.1 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Pkinase PF00069.20 CDJ63316.1 - 0.0031 16.7 0.0 0.0039 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63316.1 - 0.044 12.8 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Med3 PF11593.3 CDJ63316.1 - 4.5 6.3 15.8 4.6 6.3 11.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_11 PF13414.1 CDJ63317.1 - 4e-56 186.5 22.6 3.7e-19 68.1 1.1 5.6 5 0 0 5 5 5 5 TPR repeat TPR_1 PF00515.23 CDJ63317.1 - 1.7e-51 169.7 26.7 5.8e-09 35.1 0.0 7.4 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ63317.1 - 7.2e-41 134.8 25.5 3.4e-06 26.5 0.0 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ63317.1 - 5.6e-26 90.2 7.4 1.2e-12 47.5 0.2 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ63317.1 - 2e-20 72.9 25.9 1.7e-05 25.3 0.4 7.1 5 3 2 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ63317.1 - 2.8e-20 70.4 21.9 0.00067 19.2 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ63317.1 - 2.2e-18 65.0 16.8 0.069 13.8 0.0 9.7 7 3 3 10 10 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ63317.1 - 3.7e-16 57.5 8.4 0.00043 19.8 0.1 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ63317.1 - 5.8e-12 44.8 16.9 0.012 15.7 0.5 8.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ63317.1 - 2.9e-11 43.0 8.2 0.0018 18.1 0.0 6.6 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ63317.1 - 1.5e-08 34.8 26.8 0.00015 22.0 1.2 7.2 4 3 1 6 6 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CDJ63317.1 - 6e-08 32.7 12.6 0.00079 19.5 4.4 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CDJ63317.1 - 1.9e-06 27.6 6.0 0.73 9.8 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDJ63317.1 - 4.8e-06 26.3 11.3 0.17 11.7 0.0 6.1 5 1 1 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CDJ63317.1 - 9.9e-05 22.5 11.8 4.8 7.8 0.2 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Cytochrom_C_2 PF01322.15 CDJ63317.1 - 0.055 14.0 7.9 4.9 7.7 2.2 3.0 2 0 0 2 2 2 0 Cytochrome C' PPR PF01535.15 CDJ63317.1 - 0.073 13.0 5.7 0.35 10.9 0.1 4.1 4 0 0 4 4 3 0 PPR repeat RPN7 PF10602.4 CDJ63317.1 - 0.41 10.0 14.3 3.1 7.1 4.5 4.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Ribosomal_S17 PF00366.15 CDJ63318.1 - 2e-10 40.5 0.2 3.1e-10 39.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 His_Phos_1 PF00300.17 CDJ63320.1 - 1.5e-39 135.6 0.0 2.1e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CDJ63320.1 - 0.0044 16.4 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_60s PF00428.14 CDJ63320.1 - 0.16 12.3 4.5 0.31 11.4 3.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S17e PF00833.13 CDJ63321.1 - 2.8e-60 201.4 1.9 3.2e-60 201.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 THUMP PF02926.12 CDJ63321.1 - 0.18 11.6 1.5 0.28 11.0 0.3 1.7 1 1 1 2 2 2 0 THUMP domain SpoIIE PF07228.7 CDJ63322.1 - 0.0026 17.4 0.1 0.0026 17.4 0.1 4.0 4 0 0 4 4 4 2 Stage II sporulation protein E (SpoIIE) Abhydrolase_6 PF12697.2 CDJ63323.1 - 3.3e-22 79.4 0.8 6.1e-21 75.3 0.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDJ63323.1 - 3.8e-11 42.9 0.0 9.1e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDJ63323.1 - 1.1e-07 31.6 0.1 2.8e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Collagen PF01391.13 CDJ63323.1 - 4.1e-07 29.4 31.8 1.8e-05 24.1 13.2 2.6 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Abhydrolase_1 PF00561.15 CDJ63323.1 - 0.0024 17.4 0.0 2.1 7.8 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Thioesterase PF00975.15 CDJ63323.1 - 0.02 15.0 0.2 0.04 14.1 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain PHD PF00628.24 CDJ63324.1 - 0.00034 20.2 3.2 0.00034 20.2 2.2 3.6 3 0 0 3 3 3 1 PHD-finger zf-MIZ PF02891.15 CDJ63325.1 - 1.4e-09 37.2 2.0 4.6e-06 26.0 0.1 3.0 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger DUF3438 PF11920.3 CDJ63325.1 - 0.0071 15.2 0.1 0.0071 15.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3438) Ank_2 PF12796.2 CDJ63326.1 - 3.2e-29 101.0 0.2 1.4e-13 50.9 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ63326.1 - 5.4e-29 98.5 5.2 4.7e-09 35.6 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 CDJ63326.1 - 2.4e-22 78.8 1.7 8.6e-10 38.8 0.1 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDJ63326.1 - 3.6e-21 74.7 4.7 1.8e-06 28.0 0.0 5.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ63326.1 - 3.4e-19 67.0 0.4 8.8e-05 22.3 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat DUF4287 PF14117.1 CDJ63326.1 - 0.045 13.4 0.0 0.84 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4287) TP6A_N PF04406.9 CDJ63327.1 - 4.2e-10 39.1 0.4 1.1e-09 37.8 0.1 1.8 2 0 0 2 2 2 1 Type IIB DNA topoisomerase Sdh5 PF03937.11 CDJ63328.1 - 7.2e-12 44.8 0.1 2.7e-10 39.7 0.1 2.3 1 1 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF4347 PF14252.1 CDJ63328.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4347) Aldo_ket_red PF00248.16 CDJ63329.1 - 1.6e-36 125.6 0.0 2.1e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family LCM PF04072.9 CDJ63330.1 - 1.5e-24 86.5 0.1 1.4e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase OAR PF03826.12 CDJ63331.1 - 0.064 12.7 1.7 0.099 12.1 0.0 2.3 2 0 0 2 2 2 0 OAR domain AP2 PF00847.15 CDJ63332.1 - 2.8e-09 36.9 1.1 8.6e-09 35.4 0.8 1.8 1 0 0 1 1 1 1 AP2 domain NifU_N PF01592.11 CDJ63333.1 - 7.7e-47 158.3 0.1 9.5e-47 158.0 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Sec1 PF00995.18 CDJ63334.1 - 3e-56 191.2 0.0 2.9e-48 164.8 0.0 2.3 2 1 0 2 2 2 2 Sec1 family UPF0121 PF03661.8 CDJ63335.1 - 2e-05 23.8 0.4 3.3e-05 23.2 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) GCC2_GCC3 PF07699.8 CDJ63336.1 - 1.1e-30 104.9 116.6 7.5e-10 38.2 1.0 12.4 12 1 0 12 12 12 9 GCC2 and GCC3 HALZ PF02183.13 CDJ63336.1 - 0.41 10.4 1.4 0.76 9.5 1.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF1640 PF07798.6 CDJ63336.1 - 4.1 7.4 1.7 6.4 6.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) GldM_C PF12080.3 CDJ63336.1 - 7.4 6.4 0.0 20 5.0 0.0 1.7 1 0 0 1 1 1 0 GldM C-terminal domain RabGAP-TBC PF00566.13 CDJ63337.1 - 2.3e-36 125.2 0.1 2.3e-36 125.2 0.1 3.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CDJ63337.1 - 0.0075 16.6 0.0 0.031 14.6 0.0 2.1 1 0 0 1 1 1 1 Rhodanese-like domain RRM_1 PF00076.17 CDJ63338.1 - 3.6e-17 61.7 0.3 1.1e-16 60.1 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63338.1 - 1.3e-15 57.0 0.0 2.6e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 CDJ63338.1 - 4e-15 55.8 0.1 7e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_5 PF13893.1 CDJ63338.1 - 4.7e-07 29.5 0.1 9.5e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FMN_dh PF01070.13 CDJ63338.1 - 0.048 12.5 0.0 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF3633 PF12315.3 CDJ63340.1 - 1.1e-13 50.9 0.5 2.3e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3633) LIM PF00412.17 CDJ63340.1 - 0.3 11.1 0.0 0.1 12.6 7.6 5.1 4 1 1 5 5 5 0 LIM domain EF-hand_6 PF13405.1 CDJ63341.1 - 6e-05 22.5 0.2 7.9e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 CDJ63341.1 - 0.00022 20.2 0.1 0.00032 19.7 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CDJ63341.1 - 0.00047 19.3 0.7 0.00071 18.8 0.5 1.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CDJ63341.1 - 0.0019 18.3 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CDJ63341.1 - 0.0028 17.2 0.2 0.0039 16.7 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair Ribosomal_S17 PF00366.15 CDJ63342.1 - 3.6e-26 91.0 1.7 5e-26 90.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 PHD PF00628.24 CDJ63343.1 - 2.6e-09 36.6 6.7 2.6e-09 36.6 4.6 1.9 2 0 0 2 2 2 1 PHD-finger zf-RanBP PF00641.13 CDJ63343.1 - 0.029 13.4 0.5 0.38 9.8 0.0 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-PHD-like PF15446.1 CDJ63343.1 - 0.65 9.2 12.4 0.39 9.9 3.2 3.2 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF1900 PF08954.6 CDJ63344.1 - 6.1e-41 139.1 0.0 1.5e-40 137.8 0.0 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 CDJ63344.1 - 1.6e-20 72.1 7.9 2.4e-10 39.8 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 CDJ63344.1 - 0.00081 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A DUF1899 PF08953.6 CDJ63344.1 - 0.0013 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) AAA_13 PF13166.1 CDJ63344.1 - 0.06 11.8 15.4 0.11 10.9 10.7 1.3 1 0 0 1 1 1 0 AAA domain DUF3015 PF11220.3 CDJ63344.1 - 0.17 11.4 0.8 0.44 10.1 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3015) BLOC1_2 PF10046.4 CDJ63344.1 - 0.17 12.0 19.1 2.7 8.1 4.0 2.9 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 CDJ63344.1 - 0.17 10.9 8.4 0.76 8.8 3.1 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 CDJ63344.1 - 0.19 10.8 29.3 2.3 7.3 10.2 3.0 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 CDJ63344.1 - 0.25 11.2 33.3 0.54 10.1 22.7 1.7 1 1 1 2 2 2 0 Tropomyosin like DUF3584 PF12128.3 CDJ63344.1 - 0.3 8.3 22.8 0.39 7.9 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.1 CDJ63344.1 - 0.32 10.3 29.6 0.94 8.8 19.4 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.1 CDJ63344.1 - 0.59 10.0 29.3 0.85 9.5 9.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spectrin PF00435.16 CDJ63344.1 - 1.1 9.5 23.2 0.28 11.4 7.0 2.6 1 1 1 2 2 2 0 Spectrin repeat IncA PF04156.9 CDJ63344.1 - 6.2 6.3 32.9 5 6.6 13.1 2.2 1 1 1 2 2 2 0 IncA protein WD40 PF00400.27 CDJ63346.1 - 1.3e-24 85.1 4.0 8.2e-07 28.6 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CDJ63346.1 - 2.9e-18 65.5 0.6 6.8e-18 64.3 0.4 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex HAMP PF00672.20 CDJ63347.1 - 0.056 13.6 0.7 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 HAMP domain V-ATPase_G PF03179.10 CDJ63348.1 - 3e-26 91.7 8.9 3.5e-26 91.5 6.2 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ADPrib_exo_Tox PF03496.9 CDJ63348.1 - 0.091 11.9 0.8 0.1 11.8 0.5 1.1 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme DUF1098 PF06497.6 CDJ63348.1 - 0.17 11.9 1.7 4 7.5 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1098) HrpE PF06188.7 CDJ63348.1 - 0.42 10.3 5.1 1.2 8.8 3.5 1.7 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.13 CDJ63348.1 - 0.71 9.6 9.8 0.97 9.2 6.7 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) WD40 PF00400.27 CDJ63349.1 - 2.2e-33 112.9 22.3 3.4e-07 29.8 0.1 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDJ63349.1 - 0.13 10.9 0.0 7.8 5.1 0.0 3.2 4 0 0 4 4 4 0 Nup133 N terminal like Ribosomal_S5 PF00333.15 CDJ63350.1 - 1.2e-28 98.5 0.6 3.5e-28 97.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CDJ63350.1 - 3.1e-21 74.4 0.0 6.5e-21 73.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PRP1_N PF06424.7 CDJ63352.1 - 6.2e-50 168.9 1.9 1.8e-40 138.3 0.3 2.7 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CDJ63352.1 - 2.8e-31 105.1 31.6 0.00076 19.9 0.3 15.5 7 4 9 16 16 15 9 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ63352.1 - 2.4e-17 63.0 19.0 0.0008 19.6 0.0 10.0 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 CDJ63352.1 - 1.1e-14 53.8 10.0 0.035 13.7 0.0 9.5 7 3 3 10 10 10 3 TPR repeat TPR_16 PF13432.1 CDJ63352.1 - 1.9e-14 53.8 21.4 0.0057 17.3 0.0 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ63352.1 - 1.6e-07 31.1 6.5 0.41 10.6 0.4 7.0 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ63352.1 - 2.1e-05 24.1 19.2 4 7.5 0.2 10.3 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ63352.1 - 0.00018 21.0 0.1 1.7 8.6 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ63352.1 - 0.00031 20.6 2.7 1e+02 3.4 0.0 8.8 12 1 1 13 13 9 0 Tetratricopeptide repeat Suf PF05843.9 CDJ63352.1 - 0.00041 20.1 0.0 29 4.2 0.0 4.8 3 2 1 5 5 5 0 Suppressor of forked protein (Suf) ChAPs PF09295.5 CDJ63352.1 - 0.0018 17.0 6.9 0.81 8.3 0.1 4.0 2 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF3808 PF10300.4 CDJ63352.1 - 0.007 14.9 4.0 0.81 8.1 0.1 4.3 4 1 1 5 5 5 1 Protein of unknown function (DUF3808) TPR_21 PF09976.4 CDJ63352.1 - 0.11 12.4 14.8 0.022 14.7 1.8 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat OsmC PF02566.14 CDJ63352.1 - 0.14 12.3 1.1 27 5.0 0.1 3.6 3 0 0 3 3 3 0 OsmC-like protein TPR_6 PF13174.1 CDJ63352.1 - 0.18 12.3 13.2 27 5.4 0.1 7.9 10 0 0 10 10 9 0 Tetratricopeptide repeat Amino_oxidase PF01593.19 CDJ63353.1 - 1.2e-38 133.3 1.9 2.1e-29 102.9 0.1 2.7 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDJ63353.1 - 2.5e-11 43.4 0.2 9.1e-11 41.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CDJ63353.1 - 1.4e-06 27.4 3.7 1.4e-06 27.4 2.5 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CDJ63353.1 - 1e-05 25.5 0.3 2.1e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CDJ63353.1 - 5.2e-05 22.3 2.4 0.00013 20.9 1.7 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CDJ63353.1 - 6.2e-05 22.2 0.1 0.00012 21.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CDJ63353.1 - 0.00011 22.3 0.1 0.0004 20.5 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDJ63353.1 - 0.00057 20.2 0.4 0.0014 19.0 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDJ63353.1 - 0.0027 16.2 0.8 0.0027 16.2 0.6 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 CDJ63353.1 - 0.0068 15.3 1.9 0.012 14.5 1.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 CDJ63353.1 - 0.02 14.4 0.6 0.043 13.3 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.16 CDJ63354.1 - 9.9e-28 97.1 0.0 1.9e-24 86.4 0.0 2.0 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CDJ63354.1 - 5e-08 32.1 0.0 5.4e-07 28.7 0.0 1.9 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 CDJ63354.1 - 5.8e-08 31.7 0.0 7.2e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CDJ63354.1 - 1.7e-06 27.1 2.6 5.7e-06 25.4 1.8 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CDJ63354.1 - 1.7e-06 27.1 0.0 1.5e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CDJ63354.1 - 2.8e-05 24.2 0.1 0.0019 18.2 0.0 2.2 1 1 0 2 2 2 1 NADH(P)-binding Ribosomal_60s PF00428.14 CDJ63354.1 - 0.0058 17.0 9.7 0.014 15.7 6.1 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein XPC-binding PF09280.6 CDJ63354.1 - 0.037 13.5 1.0 1.6 8.2 0.5 2.3 2 0 0 2 2 2 0 XPC-binding domain F-box-like PF12937.2 CDJ63355.1 - 0.0032 17.1 0.6 0.0032 17.1 0.4 2.4 3 0 0 3 3 3 1 F-box-like Ribosomal_60s PF00428.14 CDJ63355.1 - 0.0066 16.8 5.2 0.0066 16.8 3.6 5.2 4 1 0 4 4 4 3 60s Acidic ribosomal protein Penaeidin PF05927.6 CDJ63355.1 - 0.031 14.8 1.4 0.031 14.8 1.0 3.1 3 0 0 3 3 3 0 Penaeidin Macoilin PF09726.4 CDJ63355.1 - 7.2 4.7 20.2 2.2 6.4 2.9 2.2 2 0 0 2 2 2 0 Transmembrane protein DUF1765 PF08578.5 CDJ63356.1 - 2.2e-09 37.4 0.1 3.9e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Sugar_transport PF06800.7 CDJ63356.1 - 0.01 14.9 0.1 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Sugar transport protein Spt20 PF12090.3 CDJ63356.1 - 0.19 11.0 1.9 12 5.1 0.1 2.4 2 0 0 2 2 2 0 Spt20 family F-box-like PF12937.2 CDJ63357.1 - 1.2e-05 24.9 5.0 0.035 13.8 0.1 2.3 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 CDJ63357.1 - 0.0091 15.6 0.2 2 8.1 0.1 2.3 2 0 0 2 2 2 2 F-box domain DUF1908 PF08926.6 CDJ63357.1 - 0.68 8.6 3.0 0.6 8.8 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) SR-25 PF10500.4 CDJ63357.1 - 1.6 8.1 7.7 3.6 7.0 5.3 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_16 PF10294.4 CDJ63358.1 - 0.041 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase zf-DHHC PF01529.15 CDJ63358.1 - 0.07 12.5 0.9 0.065 12.6 0.6 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase SDF PF00375.13 CDJ63358.1 - 0.9 8.2 3.1 0.98 8.1 2.1 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Arr-ms PF12120.3 CDJ63359.1 - 5.5e-05 23.0 6.7 0.048 13.6 0.0 3.1 1 1 2 3 3 3 2 Rifampin ADP-ribosyl transferase DUF677 PF05055.7 CDJ63359.1 - 0.00088 18.0 0.2 0.00088 18.0 0.1 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF677) AIP3 PF03915.8 CDJ63359.1 - 0.0095 14.8 1.9 0.019 13.8 1.4 1.3 1 1 0 1 1 1 1 Actin interacting protein 3 HSP90 PF00183.13 CDJ63359.1 - 0.11 10.8 0.1 6.8 4.9 0.0 2.4 1 1 1 2 2 2 0 Hsp90 protein IncA PF04156.9 CDJ63359.1 - 0.15 11.6 11.5 0.22 11.1 8.0 1.5 1 1 0 1 1 1 0 IncA protein FlgN PF05130.7 CDJ63359.1 - 0.17 12.1 9.4 0.082 13.1 4.5 1.9 2 0 0 2 2 2 0 FlgN protein Hrs_helical PF12210.3 CDJ63359.1 - 0.65 10.2 4.5 0.19 11.9 0.8 1.9 3 0 0 3 3 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF3373 PF11853.3 CDJ63359.1 - 1.9 6.9 5.5 1.9 6.9 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) DUF1180 PF06679.7 CDJ63359.1 - 5.2 6.9 9.3 11 5.8 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) bZIP_2 PF07716.10 CDJ63359.1 - 7.3 6.4 9.0 1e+02 2.8 0.0 3.3 3 0 0 3 3 3 0 Basic region leucine zipper Mnd1 PF03962.10 CDJ63359.1 - 7.6 6.1 7.8 12 5.4 4.4 1.9 1 1 1 2 2 2 0 Mnd1 family OmpH PF03938.9 CDJ63360.1 - 6.9e-06 26.0 0.4 6.9e-06 26.0 0.3 22.7 10 8 3 14 14 14 2 Outer membrane protein (OmpH-like) DUF3675 PF12428.3 CDJ63361.1 - 0.00015 21.9 0.3 0.00015 21.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3675) Synaptobrevin PF00957.16 CDJ63361.1 - 0.021 14.4 0.3 0.037 13.6 0.2 1.3 1 0 0 1 1 1 0 Synaptobrevin Amnionless PF14828.1 CDJ63361.1 - 0.022 13.2 1.6 0.027 12.9 1.1 1.1 1 0 0 1 1 1 0 Amnionless Phage_GPO PF05929.6 CDJ63361.1 - 0.05 12.8 9.1 0.078 12.2 6.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2208 PF09973.4 CDJ63361.1 - 0.12 11.5 0.2 0.12 11.5 0.1 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF1203 PF06718.6 CDJ63361.1 - 0.12 12.1 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) GP41 PF00517.12 CDJ63361.1 - 1.2 8.6 6.0 0.96 8.9 0.1 2.1 1 1 1 2 2 2 0 Retroviral envelope protein DUF948 PF06103.6 CDJ63361.1 - 2.5 8.0 5.2 1.5 8.6 1.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 CDJ63361.1 - 4 6.4 12.3 7.6 5.4 8.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Pkinase PF00069.20 CDJ63363.1 - 9.9e-64 214.9 0.1 2.2e-63 213.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63363.1 - 5.5e-38 130.5 0.3 3e-28 98.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.27 CDJ63363.1 - 3.4e-34 113.5 3.6 1.2e-06 27.3 0.0 6.5 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.1 CDJ63363.1 - 1.2e-32 111.7 0.1 2.4e-12 46.8 0.0 4.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CDJ63363.1 - 1.6e-28 95.9 4.2 2.5e-05 23.7 0.0 6.6 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.1 CDJ63363.1 - 8e-27 91.3 8.5 3.2e-07 29.4 0.0 6.7 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.1 CDJ63363.1 - 1.8e-22 78.7 2.4 2.2e-05 23.9 0.0 6.2 4 2 2 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CDJ63363.1 - 2.7e-07 30.6 2.0 0.0029 17.6 0.0 3.2 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CDJ63363.1 - 9.1e-07 28.5 1.1 0.047 13.4 0.0 3.4 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.9 CDJ63363.1 - 5.7e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CDJ63363.1 - 0.0003 19.8 0.6 0.0079 15.1 0.4 2.2 1 1 0 1 1 1 1 Kinase-like PDH PF02153.12 CDJ63363.1 - 0.0084 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase APH PF01636.18 CDJ63363.1 - 0.01 15.6 0.0 0.17 11.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_9 PF14658.1 CDJ63363.1 - 0.021 14.7 0.0 8.9 6.3 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain Choline_kinase PF01633.15 CDJ63363.1 - 0.025 14.1 0.2 0.075 12.5 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CDJ63363.1 - 0.032 13.5 0.0 0.064 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1098 PF06497.6 CDJ63363.1 - 0.14 12.1 1.3 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) SR-25 PF10500.4 CDJ63364.1 - 0.0046 16.4 21.9 0.0046 16.4 15.2 4.2 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ63364.1 - 1.6 7.6 33.7 0.021 13.9 3.3 3.1 3 0 0 3 3 3 0 Fms-interacting protein PAT1 PF09770.4 CDJ63364.1 - 1.9 6.5 60.0 2.6 6.1 41.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDJ63365.1 - 0.0024 17.3 12.1 0.0024 17.3 8.4 7.8 6 2 2 8 8 8 1 Nuclear RNA-splicing-associated protein DAP3 PF10236.4 CDJ63366.1 - 1.3e-07 30.9 0.0 3.3e-05 22.9 0.0 2.9 2 1 0 3 3 3 2 Mitochondrial ribosomal death-associated protein 3 Nitrate_red_del PF02613.10 CDJ63366.1 - 0.11 12.2 0.5 6.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Nitrate reductase delta subunit PA14 PF07691.7 CDJ63367.1 - 1.3e-16 60.5 0.0 4.8e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 PA14 domain Herpes_LMP1 PF05297.6 CDJ63367.1 - 0.13 11.2 0.8 0.2 10.5 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Cullin PF00888.17 CDJ63369.1 - 9.8e-38 130.0 0.0 2.4e-27 95.7 0.1 3.3 1 1 1 2 2 2 2 Cullin family HATPase_c_2 PF13581.1 CDJ63369.1 - 0.061 13.1 0.0 0.39 10.5 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain SopA PF13981.1 CDJ63369.1 - 0.11 12.5 0.4 1.7 8.6 0.1 2.2 2 0 0 2 2 2 0 SopA-like central domain DDHD PF02862.12 CDJ63372.1 - 0.21 11.3 14.5 0.44 10.3 9.2 1.8 2 0 0 2 2 2 0 DDHD domain TFIIA PF03153.8 CDJ63372.1 - 0.38 10.6 33.1 0.34 10.7 17.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 CDJ63372.1 - 0.85 9.1 32.1 0.063 12.8 14.7 2.9 3 0 0 3 3 3 0 IncA protein Mgr1 PF08602.5 CDJ63372.1 - 0.93 8.4 5.5 1.5 7.7 3.8 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit PAT1 PF09770.4 CDJ63372.1 - 1.6 6.8 44.3 0.099 10.8 22.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ63372.1 - 3.4 5.7 59.4 0.7 8.0 30.5 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PPP4R2 PF09184.6 CDJ63372.1 - 3.9 6.9 14.2 7.7 5.9 9.9 1.4 1 0 0 1 1 1 0 PPP4R2 DUF4175 PF13779.1 CDJ63372.1 - 4.3 4.9 54.0 0.43 8.2 30.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Asp-B-Hydro_N PF05279.6 CDJ63372.1 - 4.9 6.9 17.2 9.3 6.0 11.9 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Zip PF02535.17 CDJ63372.1 - 5.6 5.8 7.1 9.2 5.1 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 CDJ63372.1 - 6.5 6.8 22.6 9.8 6.2 12.4 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SprA-related PF12118.3 CDJ63372.1 - 6.6 5.9 40.8 8.3 5.6 0.6 2.3 2 0 0 2 2 2 0 SprA-related family OmpH PF03938.9 CDJ63372.1 - 7.3 6.5 45.1 12 5.8 26.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Raftlin PF15250.1 CDJ63372.1 - 8.9 4.7 16.8 16 3.8 11.6 1.3 1 0 0 1 1 1 0 Raftlin Abhydrolase_5 PF12695.2 CDJ63373.1 - 9.1e-24 83.8 0.2 2e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ63373.1 - 1.4e-19 70.9 0.1 1.2e-17 64.5 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ63373.1 - 4e-13 49.4 0.3 2.5e-08 33.7 0.0 2.6 2 1 1 3 3 3 2 alpha/beta hydrolase fold DLH PF01738.13 CDJ63373.1 - 3.2e-08 33.1 0.0 5.3e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 CDJ63373.1 - 9.8e-08 31.4 0.0 1.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 CDJ63373.1 - 2.6e-06 26.1 0.0 0.00027 19.5 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 CDJ63373.1 - 8.7e-06 25.3 0.0 0.0001 21.8 0.0 2.4 2 1 0 2 2 2 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 CDJ63373.1 - 8.9e-06 25.5 0.0 0.012 15.3 0.0 2.3 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 CDJ63373.1 - 2e-05 24.1 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 CDJ63373.1 - 2.2e-05 24.0 3.8 0.0041 16.5 0.0 3.2 1 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 CDJ63373.1 - 5.1e-05 22.8 0.0 0.019 14.4 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase DUF818 PF05677.7 CDJ63373.1 - 0.00038 19.2 0.0 0.00058 18.7 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.8 CDJ63373.1 - 0.00047 19.7 0.5 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1057 PF06342.7 CDJ63373.1 - 0.00049 19.0 0.0 0.017 13.9 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.20 CDJ63373.1 - 0.0075 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CDJ63373.1 - 0.0086 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 CDJ63373.1 - 0.0089 16.2 0.0 0.03 14.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain LIP PF03583.9 CDJ63373.1 - 0.01 15.0 3.0 0.28 10.3 0.0 2.9 2 1 1 3 3 3 0 Secretory lipase DUF2974 PF11187.3 CDJ63373.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2305 PF10230.4 CDJ63373.1 - 0.045 13.1 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) UPF0227 PF05728.7 CDJ63373.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) FAP PF07174.6 CDJ63374.1 - 0.013 14.7 16.8 0.018 14.3 11.6 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4231 PF14015.1 CDJ63374.1 - 0.17 11.8 1.9 0.52 10.3 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) TFIIA PF03153.8 CDJ63374.1 - 1.1 9.0 3.4 1.2 8.9 2.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAFII55_N PF04658.8 CDJ63375.1 - 8.5e-21 74.1 1.5 4e-20 71.9 0.0 2.8 3 1 0 3 3 3 1 TAFII55 protein conserved region SlyX PF04102.7 CDJ63377.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 SlyX Abhydrolase_5 PF12695.2 CDJ63378.1 - 7.9e-22 77.5 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ63378.1 - 1.7e-15 57.5 0.0 8e-14 52.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ63378.1 - 1.3e-10 41.2 0.0 3.8e-06 26.6 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 CDJ63378.1 - 7.9e-08 31.1 0.0 0.0023 16.5 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 CDJ63378.1 - 4.1e-06 26.1 0.0 1e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CDJ63378.1 - 0.00018 21.1 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CDJ63378.1 - 0.0003 20.2 0.0 0.0013 18.2 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 CDJ63378.1 - 0.00095 18.5 0.0 0.0084 15.4 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2305 PF10230.4 CDJ63378.1 - 0.00096 18.6 0.0 0.042 13.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 CDJ63378.1 - 0.0017 17.8 0.0 0.023 14.1 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 CDJ63378.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.7 CDJ63378.1 - 0.0037 16.0 0.0 0.005 15.6 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.6 CDJ63378.1 - 0.0064 16.2 0.0 0.063 12.9 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Wzy_C PF04932.10 CDJ63378.1 - 0.029 14.1 0.0 0.046 13.5 0.0 1.3 1 1 0 1 1 1 0 O-Antigen ligase PTS_EIIC PF02378.13 CDJ63378.1 - 0.27 10.0 1.7 5.3 5.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase system, EIIC LRR_6 PF13516.1 CDJ63379.1 - 0.0045 16.9 14.5 1.9 8.8 0.0 7.7 7 1 1 8 8 8 1 Leucine Rich repeat LRR_1 PF00560.28 CDJ63379.1 - 0.026 14.5 3.0 32 5.0 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat HK PF02110.10 CDJ63382.1 - 0.029 13.5 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family TMEM192 PF14802.1 CDJ63382.1 - 0.033 13.0 0.3 0.049 12.4 0.2 1.2 1 0 0 1 1 1 0 TMEM192 family DUF3527 PF12043.3 CDJ63382.1 - 0.54 9.7 5.8 0.62 9.5 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) MAT1 PF06391.8 CDJ63382.1 - 8.9 5.8 10.1 11 5.5 7.0 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TMCO5 PF14992.1 CDJ63383.1 - 0.0023 17.1 11.8 0.0026 16.9 8.2 1.1 1 0 0 1 1 1 1 TMCO5 family DUF4200 PF13863.1 CDJ63383.1 - 0.0091 15.9 22.8 0.013 15.4 15.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) CALCOCO1 PF07888.6 CDJ63383.1 - 0.013 13.8 13.6 0.015 13.6 9.4 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-Q PF13094.1 CDJ63383.1 - 0.023 14.7 16.9 0.032 14.2 11.7 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.4 CDJ63383.1 - 0.025 14.4 18.4 0.034 14.0 12.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Spc19 PF08287.6 CDJ63383.1 - 0.039 13.5 13.4 0.046 13.3 9.3 1.1 1 0 0 1 1 1 0 Spc19 Striatin PF08232.7 CDJ63383.1 - 0.045 14.0 11.2 0.071 13.4 7.8 1.3 1 0 0 1 1 1 0 Striatin family SlyX PF04102.7 CDJ63383.1 - 0.045 14.1 8.1 0.045 14.1 5.6 2.9 1 1 1 2 2 2 0 SlyX Fez1 PF06818.10 CDJ63383.1 - 0.059 13.3 18.6 0.068 13.1 12.9 1.0 1 0 0 1 1 1 0 Fez1 DUF3138 PF11336.3 CDJ63383.1 - 0.086 11.0 9.7 0.1 10.7 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) KH_5 PF13184.1 CDJ63383.1 - 0.1 12.4 0.1 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 NusA-like KH domain Rnk_N PF14760.1 CDJ63383.1 - 0.17 11.9 2.3 8.9 6.4 0.4 2.8 2 1 0 2 2 2 0 Rnk N-terminus YhfZ_C PF14503.1 CDJ63383.1 - 0.18 11.1 8.2 0.22 10.8 5.7 1.1 1 0 0 1 1 1 0 YhfZ C-terminal domain PV-1 PF06637.6 CDJ63383.1 - 0.19 10.2 16.7 0.25 9.8 11.6 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) FAM117 PF15388.1 CDJ63383.1 - 0.22 10.7 7.4 0.26 10.5 5.1 1.0 1 0 0 1 1 1 0 Protein Family FAM117 ERM PF00769.14 CDJ63383.1 - 0.22 11.0 21.3 0.26 10.7 14.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF45 PF01863.12 CDJ63383.1 - 0.23 11.2 9.1 0.28 10.9 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF724 PF05266.9 CDJ63383.1 - 0.29 10.7 15.8 0.36 10.4 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OmpH PF03938.9 CDJ63383.1 - 0.37 10.7 24.3 0.52 10.2 16.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDJ63383.1 - 0.42 8.7 19.0 0.47 8.5 13.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spc7 PF08317.6 CDJ63383.1 - 0.47 9.0 13.7 0.61 8.6 9.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 CDJ63383.1 - 0.48 7.7 21.4 0.54 7.5 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.7 CDJ63383.1 - 0.49 10.2 0.2 0.49 10.2 0.1 3.3 4 1 0 4 4 2 0 Viral A-type inclusion protein repeat Exonuc_VII_L PF02601.10 CDJ63383.1 - 0.67 9.0 11.1 0.74 8.9 7.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 CDJ63383.1 - 0.68 8.2 10.2 0.76 8.1 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mitofilin PF09731.4 CDJ63383.1 - 0.83 8.2 18.1 0.95 8.0 12.6 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WPP PF13943.1 CDJ63383.1 - 0.89 9.7 7.9 1.1 9.4 5.5 1.2 1 0 0 1 1 1 0 WPP domain HyaE PF07449.6 CDJ63383.1 - 1.3 8.9 4.4 2.3 8.1 2.5 1.7 1 1 1 2 2 2 0 Hydrogenase-1 expression protein HyaE Mnd1 PF03962.10 CDJ63383.1 - 1.5 8.4 16.3 1.9 8.1 11.3 1.2 1 0 0 1 1 1 0 Mnd1 family Gastrin PF00918.12 CDJ63383.1 - 1.5 9.6 11.8 2 9.2 8.2 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family MAT1 PF06391.8 CDJ63383.1 - 1.7 8.1 14.8 2 7.9 10.2 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Muted PF14942.1 CDJ63383.1 - 2 8.2 14.8 2.7 7.8 10.3 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein V_ATPase_I PF01496.14 CDJ63383.1 - 2.2 6.0 8.9 2.4 5.9 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 CDJ63383.1 - 2.4 8.0 24.5 0.2 11.5 5.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4174 PF13778.1 CDJ63383.1 - 2.5 8.2 8.6 3.4 7.7 5.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) Macoilin PF09726.4 CDJ63383.1 - 3.2 5.9 19.5 3.4 5.8 13.5 1.0 1 0 0 1 1 1 0 Transmembrane protein TMPIT PF07851.8 CDJ63383.1 - 3.2 6.7 9.4 3.9 6.4 6.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein IFT20 PF14931.1 CDJ63383.1 - 3.2 7.6 19.3 19 5.1 12.2 2.4 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Phlebovirus_NSM PF07246.6 CDJ63383.1 - 3.4 6.7 9.7 5.9 5.9 6.7 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2968 PF11180.3 CDJ63383.1 - 3.4 6.9 30.9 2.3 7.5 9.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Atg14 PF10186.4 CDJ63383.1 - 3.5 6.4 20.6 9.2 5.1 14.1 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CDJ63383.1 - 3.9 6.4 15.7 4.5 6.2 10.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Phage_GP20 PF06810.6 CDJ63383.1 - 6.1 6.2 16.8 8.1 5.8 5.9 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF853 PF05872.7 CDJ63383.1 - 6.2 5.0 10.3 7 4.8 7.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Borrelia_P83 PF05262.6 CDJ63383.1 - 9 4.4 15.7 10 4.2 10.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.20 CDJ63384.1 - 5e-49 166.7 0.1 1.3e-48 165.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63384.1 - 2.7e-20 72.5 1.7 6.3e-20 71.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Spt20 PF12090.3 CDJ63384.1 - 5.3 6.3 7.6 10 5.4 0.5 2.3 2 0 0 2 2 2 0 Spt20 family Peptidase_C48 PF02902.14 CDJ63385.1 - 2.8e-17 63.0 0.4 2.1e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Sporozoite_P67 PF05642.6 CDJ63385.1 - 0.019 12.8 0.0 0.019 12.8 0.0 1.8 2 1 0 2 2 2 0 Sporozoite P67 surface antigen Spt20 PF12090.3 CDJ63385.1 - 0.078 12.3 0.1 0.078 12.3 0.1 2.4 3 0 0 3 3 3 0 Spt20 family Macoilin PF09726.4 CDJ63385.1 - 7 4.7 12.3 0.33 9.1 3.9 1.9 2 0 0 2 2 2 0 Transmembrane protein CM_1 PF07736.6 CDJ63386.1 - 0.091 12.8 0.8 0.21 11.7 0.6 1.6 1 0 0 1 1 1 0 Chorismate mutase type I Neur_chan_memb PF02932.11 CDJ63386.1 - 0.16 11.8 3.6 2.2 8.1 2.5 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Glt_symporter PF03616.9 CDJ63386.1 - 1.1 7.6 5.5 0.098 11.1 0.2 1.8 2 0 0 2 2 2 0 Sodium/glutamate symporter CD20 PF04103.10 CDJ63387.1 - 0.14 12.0 4.1 0.35 10.8 0.2 2.5 2 0 0 2 2 2 0 CD20-like family XK-related PF09815.4 CDJ63387.1 - 0.56 9.1 3.3 1.1 8.2 2.3 1.4 1 0 0 1 1 1 0 XK-related protein PAT1 PF09770.4 CDJ63387.1 - 0.77 7.9 39.3 1.1 7.4 27.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDJ63387.1 - 5.1 6.3 43.2 4.9 6.3 12.1 2.4 2 1 0 2 2 2 0 SprA-related family Gp_dh_C PF02800.15 CDJ63389.1 - 2e-57 193.0 0.0 1.3e-41 141.6 0.0 2.4 1 1 1 2 2 2 2 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CDJ63389.1 - 9.6e-50 168.4 0.0 2e-49 167.4 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CDJ63389.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 CDJ63389.1 - 0.17 11.8 1.2 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus CDK2AP PF09806.4 CDJ63389.1 - 1.1 9.3 25.0 0.27 11.4 1.4 2.6 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PRP3 PF08572.5 CDJ63390.1 - 1.6e-07 30.9 10.3 1.6e-07 30.9 7.1 4.7 5 1 1 6 6 6 3 pre-mRNA processing factor 3 (PRP3) Suf PF05843.9 CDJ63391.1 - 8.4 6.0 25.0 0.75 9.4 9.5 2.8 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ63392.1 - 0.00069 17.9 31.7 0.00089 17.6 21.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDJ63392.1 - 0.017 15.4 15.9 0.022 15.0 11.0 1.1 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.8 CDJ63392.1 - 0.61 9.9 39.4 0.74 9.6 27.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 CDJ63392.1 - 5.8 6.3 79.9 0.64 9.4 33.0 2.6 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein CDC27 PF09507.5 CDJ63392.1 - 6.5 5.8 40.1 7.6 5.6 27.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SprA-related PF12118.3 CDJ63392.1 - 6.5 5.9 62.3 12 5.1 43.2 1.4 1 1 0 1 1 1 0 SprA-related family GCS PF03074.11 CDJ63393.1 - 8.4e-89 298.2 0.2 2.8e-56 191.1 0.1 3.4 2 2 0 2 2 2 2 Glutamate-cysteine ligase DUF1635 PF07795.6 CDJ63394.1 - 0.4 10.0 5.7 0.61 9.4 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) NPR3 PF03666.8 CDJ63394.1 - 0.47 8.9 3.5 0.59 8.6 2.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PLRV_ORF5 PF01690.12 CDJ63394.1 - 1 8.4 7.8 1.3 8.1 5.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Hid1 PF12722.2 CDJ63394.1 - 1.1 6.8 6.5 1.2 6.7 4.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pap_E4 PF02711.9 CDJ63394.1 - 1.1 10.1 5.7 1.8 9.3 3.9 1.3 1 0 0 1 1 1 0 E4 protein Mitofilin PF09731.4 CDJ63394.1 - 1.3 7.5 18.6 1.6 7.2 12.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF966 PF06136.8 CDJ63394.1 - 1.8 7.9 13.1 2.2 7.6 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S64 PF08192.6 CDJ63394.1 - 2 6.6 12.7 2 6.6 8.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Herpes_TAF50 PF03326.8 CDJ63394.1 - 2 7.2 19.6 2.4 7.0 13.6 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Opi1 PF08618.5 CDJ63394.1 - 2.1 7.1 23.2 2.8 6.7 16.1 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DMAP_binding PF06464.6 CDJ63394.1 - 2.6 8.6 8.6 1.3 9.6 3.5 1.9 2 0 0 2 2 2 0 DMAP1-binding Domain Miff PF05644.6 CDJ63394.1 - 2.7 7.5 5.6 2.9 7.4 3.8 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Draxin PF15550.1 CDJ63394.1 - 4.1 6.9 8.4 5.1 6.6 5.8 1.1 1 0 0 1 1 1 0 Draxin Hex_IIIa PF02455.11 CDJ63394.1 - 4.3 5.9 8.1 5.2 5.6 5.6 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) TFIIF_alpha PF05793.7 CDJ63394.1 - 4.4 5.5 9.8 5.4 5.2 6.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DHHW PF14286.1 CDJ63394.1 - 5.1 6.3 8.1 5.6 6.1 5.6 1.2 1 0 0 1 1 1 0 DHHW protein Neur_chan_memb PF02932.11 CDJ63394.1 - 5.6 6.7 6.8 6.7 6.5 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_BLLF1 PF05109.8 CDJ63394.1 - 6.3 4.6 13.6 7 4.4 9.5 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) NuA4 PF09340.5 CDJ63395.1 - 4.5e-19 67.8 0.0 1.3e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Herpes_US12 PF05363.7 CDJ63395.1 - 0.00043 20.7 0.2 0.0012 19.2 0.2 1.8 1 0 0 1 1 1 1 Herpesvirus US12 family Histone_HNS PF00816.16 CDJ63395.1 - 0.2 12.1 0.0 0.2 12.1 0.0 3.0 4 0 0 4 4 4 0 H-NS histone family MAP65_ASE1 PF03999.7 CDJ63395.1 - 7.8 4.9 7.3 9.2 4.7 5.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) OPA3 PF07047.7 CDJ63396.1 - 4.9e-32 110.4 2.4 4.9e-32 110.4 1.7 1.7 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) Spt20 PF12090.3 CDJ63396.1 - 0.0014 18.0 5.0 0.0016 17.8 3.5 1.2 1 0 0 1 1 1 1 Spt20 family OATP PF03137.15 CDJ63396.1 - 0.0023 16.0 1.0 0.0027 15.8 0.7 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family RAB3GAP2_N PF14655.1 CDJ63396.1 - 0.004 16.2 1.7 0.0045 16.0 1.2 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Shisa PF13908.1 CDJ63396.1 - 0.0057 16.8 0.6 0.0071 16.5 0.4 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.9 CDJ63396.1 - 0.0073 15.9 16.3 0.01 15.4 11.3 1.2 1 0 0 1 1 1 1 IncA protein RskA PF10099.4 CDJ63396.1 - 0.034 13.8 1.2 0.049 13.3 0.8 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ctr PF04145.10 CDJ63396.1 - 0.055 13.5 1.9 0.086 12.8 1.3 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF2561 PF10812.3 CDJ63396.1 - 0.057 13.0 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Herpes_gE PF02480.11 CDJ63396.1 - 0.082 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_glycop PF01528.11 CDJ63396.1 - 0.09 11.4 0.9 0.11 11.1 0.6 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF1211 PF06736.6 CDJ63396.1 - 0.15 12.2 1.0 0.67 10.1 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) Med15 PF09606.5 CDJ63396.1 - 0.18 9.9 23.1 0.21 9.7 16.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4199 PF13858.1 CDJ63396.1 - 0.27 11.1 3.3 0.4 10.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PXA PF02194.10 CDJ63396.1 - 0.29 10.6 6.6 0.43 10.1 4.6 1.3 1 0 0 1 1 1 0 PXA domain DUF3617 PF12276.3 CDJ63396.1 - 0.47 9.8 7.3 0.73 9.2 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) DUF4557 PF15101.1 CDJ63396.1 - 1.1 9.0 9.8 1.3 8.7 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SprA-related PF12118.3 CDJ63396.1 - 1.2 8.3 20.1 1.7 7.8 13.9 1.2 1 0 0 1 1 1 0 SprA-related family 60KD_IMP PF02096.15 CDJ63396.1 - 2 8.0 10.8 2.9 7.4 7.5 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Serinc PF03348.10 CDJ63396.1 - 5.3 5.6 10.8 5.5 5.5 7.1 1.3 1 1 0 1 1 1 0 Serine incorporator (Serinc) BAF1_ABF1 PF04684.8 CDJ63396.1 - 5.6 5.7 20.1 7.1 5.3 13.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF912 PF06024.7 CDJ63396.1 - 8 6.5 7.4 12 6.0 4.8 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) tRNA_bind PF01588.15 CDJ63398.1 - 3.3e-24 84.5 0.0 6.2e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 CDJ63398.1 - 4.4e-06 27.0 0.0 4.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDJ63398.1 - 7.2e-06 25.9 0.1 7.2e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain BAF1_ABF1 PF04684.8 CDJ63398.1 - 0.0079 15.1 12.2 0.014 14.2 8.4 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor GST_C_2 PF13410.1 CDJ63398.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mucin PF01456.12 CDJ63398.1 - 0.1 12.3 0.1 0.1 12.3 0.1 3.5 2 1 1 3 3 1 0 Mucin-like glycoprotein CDC27 PF09507.5 CDJ63398.1 - 0.12 11.6 9.5 0.16 11.1 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2201_N PF13203.1 CDJ63398.1 - 0.37 9.9 11.5 0.51 9.4 8.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDK2AP PF09806.4 CDJ63398.1 - 0.45 10.7 15.8 0.97 9.6 10.9 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Suf PF05843.9 CDJ63398.1 - 1.4 8.6 5.3 2 8.0 3.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.4 CDJ63398.1 - 2.5 6.2 8.5 3.6 5.7 5.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Spt20 PF12090.3 CDJ63399.1 - 2 7.7 15.5 0.087 12.1 5.6 2.4 2 0 0 2 2 2 0 Spt20 family Abhydrolase_5 PF12695.2 CDJ63400.1 - 1.7e-16 60.2 0.9 4.8e-16 58.8 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ63400.1 - 9e-16 58.4 2.2 1.6e-15 57.6 1.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CDJ63400.1 - 8.7e-08 31.0 0.1 0.00031 19.3 0.0 3.0 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 CDJ63400.1 - 5.3e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 CDJ63400.1 - 6.7e-06 25.8 0.2 1.2e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDJ63400.1 - 0.00062 19.0 0.0 0.078 12.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 CDJ63400.1 - 0.002 17.9 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 CDJ63400.1 - 0.016 14.8 0.1 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3446 PF11928.3 CDJ63400.1 - 0.87 9.8 11.3 0.17 12.1 4.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF3682 PF12446.3 CDJ63402.1 - 0.018 15.3 23.4 0.018 15.3 16.3 6.7 3 2 3 6 6 6 0 Protein of unknown function (DUF3682) Utp14 PF04615.8 CDJ63402.1 - 0.18 9.9 54.3 0.21 9.7 37.6 1.1 1 0 0 1 1 1 0 Utp14 protein Caldesmon PF02029.10 CDJ63402.1 - 1.3 7.4 39.1 0.58 8.5 7.6 2.2 2 0 0 2 2 2 0 Caldesmon Ribosomal_S4e PF00900.15 CDJ63403.1 - 9.8e-16 57.2 0.0 2.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal family S4e KOW PF00467.24 CDJ63403.1 - 0.00022 20.7 1.5 0.00022 20.7 1.1 2.1 2 0 0 2 2 2 1 KOW motif Ribosomal_60s PF00428.14 CDJ63404.1 - 0.19 12.1 5.4 0.3 11.4 3.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3678 PF12435.3 CDJ63405.1 - 0.51 9.9 3.3 0.58 9.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DUF3123 PF11321.3 CDJ63405.1 - 1.5 9.1 5.8 1.5 9.0 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) TSA PF03249.8 CDJ63405.1 - 1.6 7.1 9.6 1.6 7.2 6.7 1.0 1 0 0 1 1 1 0 Type specific antigen DUF2681 PF10883.3 CDJ63405.1 - 8.4 6.6 7.2 8.4 6.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Spt20 PF12090.3 CDJ63406.1 - 0.13 11.5 2.2 0.18 11.1 1.5 1.3 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.4 CDJ63406.1 - 0.15 10.2 21.7 0.17 10.0 15.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDJ63406.1 - 0.18 11.6 7.0 0.27 11.0 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FimP PF09766.4 CDJ63406.1 - 0.8 8.7 10.6 1.1 8.2 6.6 1.6 2 0 0 2 2 2 0 Fms-interacting protein Pex16 PF08610.5 CDJ63406.1 - 1.8 7.4 5.5 2.7 6.8 3.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Suf PF05843.9 CDJ63406.1 - 3.5 7.2 6.8 5 6.7 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) JCAD PF15351.1 CDJ63407.1 - 0.78 7.2 3.6 0.26 8.8 0.1 1.8 2 0 0 2 2 2 0 Junctional protein associated with coronary artery disease Secretin_N_2 PF07655.8 CDJ63408.1 - 4.7 7.6 19.1 6 7.3 13.2 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Period_C PF12114.3 CDJ63408.1 - 9.3 5.7 13.5 10 5.7 9.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 CDJ63408.1 - 9.8 4.3 18.1 10 4.2 12.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L18e PF00828.14 CDJ63411.1 - 3.9e-12 46.6 0.4 3.7e-05 24.0 0.2 3.1 2 0 0 2 2 2 2 Ribosomal protein L18e/L15 Mem_trans PF03547.13 CDJ63411.1 - 0.0012 17.2 0.3 0.0012 17.2 0.2 2.6 3 0 0 3 3 3 1 Membrane transport protein Memo PF01875.12 CDJ63412.1 - 1.3e-35 122.6 0.0 2.1e-31 108.8 0.0 2.0 1 1 1 2 2 2 2 Memo-like protein Acetyltransf_2 PF00797.12 CDJ63414.1 - 0.082 12.4 3.8 1.2 8.6 2.2 2.1 2 0 0 2 2 2 0 N-acetyltransferase DUF3573 PF12097.3 CDJ63414.1 - 2.8 6.4 4.2 3.7 6.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Herpes_BLRF2 PF05812.7 CDJ63415.1 - 0.005 16.6 3.5 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein HDAC4_Gln PF12203.3 CDJ63415.1 - 0.023 14.6 8.8 0.041 13.8 6.1 1.4 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 SoxE PF06525.6 CDJ63415.1 - 6.3 6.0 7.2 11 5.2 5.0 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) AP2 PF00847.15 CDJ63416.1 - 5.5e-06 26.4 1.4 5.5e-06 26.4 1.0 10.4 11 2 2 13 13 13 3 AP2 domain Ctr PF04145.10 CDJ63417.1 - 1e-18 67.7 2.2 1e-18 67.7 1.5 3.0 2 2 0 2 2 2 1 Ctr copper transporter family SPX PF03105.14 CDJ63418.1 - 0.00063 19.6 13.2 0.00073 19.3 9.2 1.1 1 0 0 1 1 1 1 SPX domain SprA-related PF12118.3 CDJ63418.1 - 0.0022 17.3 39.1 0.0045 16.3 27.1 1.5 1 0 0 1 1 1 1 SprA-related family Herpes_env PF01673.13 CDJ63418.1 - 0.004 15.7 5.0 0.0046 15.5 3.4 1.1 1 0 0 1 1 1 1 Herpesvirus putative major envelope glycoprotein Peptidase_S46 PF10459.4 CDJ63418.1 - 0.029 12.8 16.0 0.032 12.6 11.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Exonuc_VII_L PF02601.10 CDJ63418.1 - 0.03 13.5 13.0 0.033 13.3 9.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDC45 PF02724.9 CDJ63418.1 - 0.049 11.6 18.6 0.061 11.3 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein MRP-S31 PF15433.1 CDJ63418.1 - 0.055 12.8 22.0 0.093 12.1 15.3 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DDHD PF02862.12 CDJ63418.1 - 0.098 12.4 18.1 0.14 11.9 12.5 1.2 1 0 0 1 1 1 0 DDHD domain LMBR1 PF04791.11 CDJ63418.1 - 0.15 10.6 3.4 0.15 10.5 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Spore_coat_CotO PF14153.1 CDJ63418.1 - 0.15 11.4 26.4 0.036 13.5 15.9 1.7 2 0 0 2 2 2 0 Spore coat protein CotO Pox_Ag35 PF03286.9 CDJ63418.1 - 0.16 11.4 12.5 0.23 10.9 8.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CMV_1a PF12467.3 CDJ63418.1 - 0.25 11.6 14.9 0.41 11.0 10.4 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF4045 PF13254.1 CDJ63418.1 - 0.36 10.0 16.4 0.46 9.7 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DHHW PF14286.1 CDJ63418.1 - 0.48 9.6 14.5 0.63 9.2 10.1 1.1 1 0 0 1 1 1 0 DHHW protein SAPS PF04499.10 CDJ63418.1 - 0.49 8.9 17.7 0.61 8.6 12.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CDJ63418.1 - 0.98 7.0 24.3 1.3 6.6 16.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDJ63418.1 - 1.1 7.5 15.0 1.4 7.2 10.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ycf1 PF05758.7 CDJ63418.1 - 1.4 6.4 18.7 1.8 6.2 13.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 CDJ63418.1 - 1.7 7.7 25.3 2.4 7.2 17.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Membralin PF09746.4 CDJ63418.1 - 1.7 7.6 8.5 2.2 7.2 5.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein PPP4R2 PF09184.6 CDJ63418.1 - 1.7 8.1 16.5 2.3 7.7 11.4 1.1 1 0 0 1 1 1 0 PPP4R2 Pal1 PF08316.6 CDJ63418.1 - 1.7 9.0 8.7 3.2 8.2 6.1 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein FAM60A PF15396.1 CDJ63418.1 - 2.4 7.8 19.5 3.5 7.3 13.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Cellulose_synt PF03552.9 CDJ63418.1 - 2.9 6.0 7.0 3.6 5.7 4.8 1.1 1 0 0 1 1 1 0 Cellulose synthase eIF-3_zeta PF05091.7 CDJ63418.1 - 3.3 6.2 21.6 4.6 5.7 15.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.11 CDJ63418.1 - 3.3 7.5 15.4 4.8 7.0 10.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.1 CDJ63418.1 - 3.6 7.7 18.5 6.6 6.9 12.8 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Asp-B-Hydro_N PF05279.6 CDJ63418.1 - 4.2 7.1 20.0 5.9 6.6 13.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RP-C_C PF11800.3 CDJ63418.1 - 5 6.7 23.1 0.83 9.3 12.0 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region TFIIA PF03153.8 CDJ63418.1 - 5 6.9 41.4 0.35 10.7 25.3 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.14 CDJ63418.1 - 5.3 4.7 13.0 7.7 4.2 9.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF3_subunit PF08597.5 CDJ63418.1 - 5.8 6.4 22.9 9 5.7 15.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Mem_trans PF03547.13 CDJ63418.1 - 6.3 4.9 7.6 4.9 5.3 4.1 1.7 2 0 0 2 2 2 0 Membrane transport protein Zip PF02535.17 CDJ63418.1 - 6.8 5.6 7.7 11 4.9 5.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.4 CDJ63418.1 - 7.6 6.4 30.4 13 5.6 21.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SOBP PF15279.1 CDJ63419.1 - 0.072 13.4 12.9 0.11 12.8 9.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_M19 PF01244.16 CDJ63419.1 - 2.7 6.8 6.7 0.086 11.7 0.3 1.6 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) SseC PF04888.7 CDJ63420.1 - 6.1 6.0 31.6 1.4 8.2 1.3 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family MR_MLE_C PF13378.1 CDJ63421.1 - 3.9 7.4 8.6 5.1 7.1 0.1 3.2 4 0 0 4 4 4 0 Enolase C-terminal domain-like Herpes_UL87 PF03043.9 CDJ63423.1 - 2.1 6.6 6.5 0.59 8.4 1.1 2.2 2 0 0 2 2 2 0 Herpesvirus UL87 family Metallophos PF00149.23 CDJ63425.1 - 1.3e-07 31.2 0.0 5.8e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDJ63425.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain LRR_4 PF12799.2 CDJ63427.1 - 1.5 8.5 8.5 1.5 8.5 0.5 3.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CDJ63427.1 - 3.6 7.9 7.6 0.41 10.8 0.2 3.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 CDJ63427.1 - 7.1 7.3 5.8 7 7.3 0.1 3.0 3 0 0 3 3 3 0 Leucine rich repeat zf-Tim10_DDP PF02953.10 CDJ63428.1 - 2e-10 39.8 1.5 3.9e-10 38.8 1.0 1.5 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SR-25 PF10500.4 CDJ63428.1 - 0.022 14.2 11.0 0.03 13.7 7.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_M24 PF00557.19 CDJ63428.1 - 0.27 10.7 3.1 0.16 11.5 0.6 1.7 1 1 0 1 1 1 0 Metallopeptidase family M24 TraT PF05818.7 CDJ63428.1 - 0.51 9.7 8.3 0.78 9.1 5.7 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein FAM70 PF14967.1 CDJ63428.1 - 0.66 9.1 5.7 0.87 8.7 3.9 1.1 1 0 0 1 1 1 0 FAM70 protein DNA_pol_viral_N PF00242.12 CDJ63428.1 - 1.4 7.9 6.3 1.9 7.4 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF755 PF05501.6 CDJ63428.1 - 4.4 7.3 14.7 9.4 6.3 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) HRXXH PF13933.1 CDJ63428.1 - 8.4 5.7 7.8 19 4.5 5.4 1.6 1 1 0 1 1 1 0 Putative peptidase family DUF755 PF05501.6 CDJ63429.1 - 0.0011 18.9 17.2 0.0011 18.9 12.0 3.2 3 0 0 3 3 2 1 Domain of unknown function (DUF755) Activator_LAG-3 PF11498.3 CDJ63429.1 - 0.0015 17.4 10.4 0.0015 17.4 7.2 2.2 2 0 0 2 2 2 1 Transcriptional activator LAG-3 FliD_N PF02465.13 CDJ63429.1 - 0.0054 17.0 6.2 0.0054 17.0 4.3 3.1 2 1 0 2 2 1 1 Flagellar hook-associated protein 2 N-terminus Dehydrin PF00257.14 CDJ63429.1 - 0.012 15.8 2.8 0.012 15.8 2.0 2.5 2 1 0 2 2 2 0 Dehydrin SR-25 PF10500.4 CDJ63429.1 - 0.013 14.9 14.9 0.013 14.9 10.3 3.2 2 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDJ63429.1 - 2.2 6.3 29.8 3.4 5.8 20.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDJ63429.1 - 3.5 6.5 19.7 1 8.3 2.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein Herpes_capsid PF06112.6 CDJ63429.1 - 8.1 6.4 25.5 0.78 9.7 5.2 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF4175 PF13779.1 CDJ63429.1 - 9 3.8 33.0 0.098 10.3 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF106 PF01956.11 CDJ63429.1 - 9.1 5.7 6.7 5 6.6 1.6 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 RGM_N PF06535.7 CDJ63429.1 - 9.1 6.2 9.2 1.3 9.0 1.8 2.5 2 1 0 3 3 3 0 Repulsive guidance molecule (RGM) N-terminus Ribosomal_60s PF00428.14 CDJ63430.1 - 0.32 11.4 48.9 0.71 10.3 7.2 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein ASFV_J13L PF05568.6 CDJ63431.1 - 0.009 15.5 6.5 0.009 15.5 3.6 1.7 1 1 1 2 2 2 1 African swine fever virus J13L protein Corona_nucleoca PF00937.13 CDJ63431.1 - 0.19 10.6 12.9 0.31 9.9 8.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Macoilin PF09726.4 CDJ63431.1 - 0.57 8.3 9.7 0.7 8.1 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein CBF PF03914.12 CDJ63433.1 - 1.9e-19 69.6 0.0 1.9e-19 69.6 0.0 4.0 4 1 0 5 5 5 1 CBF/Mak21 family LMBR1 PF04791.11 CDJ63434.1 - 0.004 15.8 13.0 0.0046 15.6 9.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Ycf1 PF05758.7 CDJ63434.1 - 0.0077 14.0 25.0 0.011 13.5 17.3 1.3 1 0 0 1 1 1 1 Ycf1 Neur_chan_memb PF02932.11 CDJ63434.1 - 0.061 13.2 18.3 0.079 12.8 12.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.7 CDJ63434.1 - 0.078 12.9 23.5 0.11 12.4 16.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 CDJ63434.1 - 1.5 6.4 34.8 1.8 6.1 24.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lin-8 PF03353.10 CDJ63434.1 - 2.4 7.3 36.5 3.1 6.9 25.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PLRV_ORF5 PF01690.12 CDJ63434.1 - 2.6 7.0 34.9 3.2 6.7 24.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 CDJ63434.1 - 3.1 6.1 35.9 3.7 5.9 24.8 1.1 1 0 0 1 1 1 0 Daxx Family Draxin PF15550.1 CDJ63434.1 - 6.3 6.3 32.0 8.1 5.9 22.2 1.1 1 0 0 1 1 1 0 Draxin Herpes_env PF01673.13 CDJ63434.1 - 8.5 4.8 20.4 12 4.3 14.2 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein CRT10 PF08728.5 CDJ63434.1 - 9 4.1 15.0 9.9 4.0 10.4 1.0 1 0 0 1 1 1 0 CRT10 PAT1 PF09770.4 CDJ63435.1 - 0.088 11.0 11.8 0.11 10.7 8.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SLD3 PF08639.5 CDJ63435.1 - 0.12 10.9 6.4 0.13 10.9 4.4 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 Ribosomal_S30 PF04758.9 CDJ63437.1 - 1.6e-25 88.5 4.3 2.2e-25 88.1 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 DUF445 PF04286.7 CDJ63439.1 - 0.081 12.4 3.3 0.16 11.4 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3818 PF12825.2 CDJ63439.1 - 0.14 10.8 2.0 0.23 10.0 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) AalphaY_MDB PF04611.7 CDJ63439.1 - 0.21 11.4 3.7 0.098 12.5 0.2 2.3 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region DUF883 PF05957.8 CDJ63439.1 - 3.1 8.2 15.3 0.46 10.9 4.3 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ThiF PF00899.16 CDJ63440.1 - 3.6e-33 114.2 0.2 4.3e-19 68.6 0.0 4.4 4 0 0 4 4 4 3 ThiF family UBACT PF02134.16 CDJ63440.1 - 9.4e-11 41.1 0.0 3.6e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 CDJ63440.1 - 6.7e-08 32.7 0.0 1.5e-06 28.3 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 CDJ63440.1 - 3.8e-06 26.1 0.1 1.8e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site 2-Hacid_dh_C PF02826.14 CDJ63440.1 - 3.4e-05 23.0 0.0 0.032 13.3 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CDJ63440.1 - 0.0013 18.7 4.4 0.22 11.6 0.0 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CDJ63440.1 - 0.0027 18.0 1.3 1.8 9.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CDJ63440.1 - 0.012 15.8 0.0 0.5 10.6 0.0 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 CDJ63440.1 - 0.029 14.0 0.1 3.3 7.3 0.0 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ComFB PF10719.4 CDJ63440.1 - 0.054 13.2 0.1 4.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Late competence development protein ComFB PcF PF09461.5 CDJ63440.1 - 0.07 13.0 1.1 0.18 11.7 0.8 1.6 1 0 0 1 1 1 0 Phytotoxin PcF protein Apc4_WD40 PF12894.2 CDJ63441.1 - 0.0002 20.8 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain rve PF00665.21 CDJ63443.1 - 4.3e-07 30.0 0.1 6.9e-07 29.3 0.0 1.3 2 0 0 2 2 2 1 Integrase core domain Ras PF00071.17 CDJ63444.1 - 2e-59 199.6 0.0 2.5e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ63444.1 - 6.9e-18 65.2 0.0 9.7e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDJ63444.1 - 7.9e-13 48.0 0.0 1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDJ63444.1 - 7.2e-07 28.5 0.0 8.9e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CDJ63444.1 - 0.0004 20.3 0.0 0.00065 19.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDJ63444.1 - 0.0033 16.8 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CDJ63444.1 - 0.026 13.8 0.0 0.064 12.5 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B MORN PF02493.15 CDJ63445.1 - 2.6e-50 165.2 51.2 1.1e-06 28.0 0.7 10.2 10 0 0 10 10 10 10 MORN repeat SM-ATX PF14438.1 CDJ63445.1 - 0.15 12.0 4.6 68 3.4 0.0 5.1 5 0 0 5 5 5 0 Ataxin 2 SM domain Pkinase PF00069.20 CDJ63446.1 - 6e-38 130.4 0.0 1.6e-27 96.2 0.0 4.7 3 2 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63446.1 - 3.3e-35 121.3 0.0 1.4e-25 89.8 0.0 5.1 3 2 0 3 3 3 2 Protein tyrosine kinase AAA PF00004.24 CDJ63447.1 - 1e-16 61.2 0.0 1.8e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CDJ63447.1 - 3.2e-13 49.4 0.0 8.7e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CDJ63447.1 - 3.7e-12 46.2 0.0 4.8e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase III, delta subunit AAA_22 PF13401.1 CDJ63447.1 - 5.1e-08 33.1 0.1 1.5e-06 28.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDJ63447.1 - 8e-07 29.2 0.2 8.7e-05 22.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CDJ63447.1 - 1.8e-06 27.6 0.1 1.4e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 CDJ63447.1 - 3.5e-06 26.9 0.0 5.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CDJ63447.1 - 9.1e-06 24.8 0.0 2e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 CDJ63447.1 - 1e-05 25.2 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDJ63447.1 - 1.1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CDJ63447.1 - 0.0018 17.9 0.1 0.01 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 CDJ63447.1 - 0.0021 17.5 0.1 0.083 12.3 0.0 2.2 1 1 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 CDJ63447.1 - 0.0034 16.4 0.0 0.0064 15.5 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 CDJ63447.1 - 0.0095 15.4 0.1 2.7 7.3 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_33 PF13671.1 CDJ63447.1 - 0.016 15.0 0.1 0.033 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CDJ63447.1 - 0.017 14.5 0.1 0.23 10.8 0.0 2.1 1 1 0 2 2 2 0 AAA domain Rad17 PF03215.10 CDJ63447.1 - 0.019 13.6 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 CDJ63447.1 - 0.024 13.8 0.1 0.17 11.0 0.1 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI TOBE PF03459.12 CDJ63447.1 - 0.042 13.9 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 TOBE domain AAA_3 PF07726.6 CDJ63447.1 - 0.042 13.4 0.1 0.52 9.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CDJ63447.1 - 0.043 13.0 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 CDJ63447.1 - 0.046 13.5 0.0 0.2 11.4 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 CDJ63447.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 CDJ63447.1 - 0.068 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 CDJ63447.1 - 0.13 11.8 0.0 0.38 10.3 0.0 1.7 1 1 0 1 1 1 0 NACHT domain Filament PF00038.16 CDJ63449.1 - 0.012 15.1 21.4 0.19 11.1 6.5 2.3 1 1 1 2 2 2 0 Intermediate filament protein Syntaxin-6_N PF09177.6 CDJ63449.1 - 0.017 15.4 7.5 0.017 15.4 5.2 2.3 2 1 0 3 3 2 0 Syntaxin 6, N-terminal Phage_GPO PF05929.6 CDJ63449.1 - 0.023 13.9 8.8 0.034 13.4 6.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.7 CDJ63449.1 - 0.027 14.2 11.4 0.14 11.9 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.7 CDJ63449.1 - 0.043 13.1 20.3 0.54 9.5 7.9 2.2 1 1 1 2 2 2 0 PspA/IM30 family FliJ PF02050.11 CDJ63449.1 - 0.05 13.6 18.2 0.73 9.9 5.5 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein CagA PF03507.8 CDJ63449.1 - 0.051 13.4 0.7 0.051 13.4 0.5 2.1 1 1 1 2 2 2 0 CagA exotoxin DUF883 PF05957.8 CDJ63449.1 - 0.069 13.5 8.3 0.44 10.9 1.2 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) CDC37_N PF03234.9 CDJ63449.1 - 0.1 12.9 12.1 0.13 12.5 8.4 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding IFT46_B_C PF12317.3 CDJ63449.1 - 0.12 11.7 1.6 0.2 11.0 1.0 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal AAA_13 PF13166.1 CDJ63449.1 - 0.14 10.6 12.6 0.16 10.3 8.7 1.1 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.6 CDJ63449.1 - 0.22 11.3 6.5 1.2 8.9 0.4 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 CDJ63449.1 - 0.28 11.0 9.5 2.3 8.0 1.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cor1 PF04803.7 CDJ63449.1 - 0.31 10.7 13.7 0.023 14.4 3.9 2.4 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Spc7 PF08317.6 CDJ63449.1 - 0.36 9.4 16.1 0.81 8.2 10.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.1 CDJ63449.1 - 0.38 9.8 19.6 0.14 11.3 6.6 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Nup88 PF10168.4 CDJ63449.1 - 0.5 8.1 12.3 0.57 7.9 8.5 1.1 1 0 0 1 1 1 0 Nuclear pore component TMV_coat PF00721.16 CDJ63449.1 - 0.66 9.8 4.5 1.4 8.8 2.7 1.9 1 1 1 2 2 2 0 Virus coat protein (TMV like) DUF3994 PF13159.1 CDJ63449.1 - 0.82 9.9 3.8 0.86 9.8 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3994) ATP-synt_DE PF00401.15 CDJ63449.1 - 1 9.2 9.6 0.27 11.1 0.3 2.9 2 1 1 3 3 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Spectrin PF00435.16 CDJ63449.1 - 1.1 9.5 16.6 4.1 7.7 6.0 2.5 1 1 1 2 2 2 0 Spectrin repeat FlxA PF14282.1 CDJ63449.1 - 1.3 9.0 18.9 0.51 10.3 9.5 2.3 2 1 0 2 2 2 0 FlxA-like protein ACCA PF03255.9 CDJ63449.1 - 1.7 8.1 9.6 0.41 10.1 0.8 2.5 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit BLOC1_2 PF10046.4 CDJ63449.1 - 1.8 8.7 12.0 2.3 8.3 2.2 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tweety PF04906.8 CDJ63449.1 - 1.8 6.8 6.0 3 6.1 1.6 1.9 1 1 1 2 2 2 0 Tweety DUF972 PF06156.8 CDJ63449.1 - 2.1 8.7 18.8 5.4 7.4 1.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Spore_III_AB PF09548.5 CDJ63449.1 - 2.3 7.9 8.4 0.49 10.1 0.2 2.4 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF3584 PF12128.3 CDJ63449.1 - 2.4 5.4 20.2 5.9 4.0 14.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 CDJ63449.1 - 2.4 7.0 19.2 1.1 8.1 1.3 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 CDJ63449.1 - 2.4 7.9 28.7 0.45 10.3 8.7 2.7 1 1 1 2 2 2 0 Tropomyosin like Glycoprotein_B PF00606.13 CDJ63449.1 - 2.4 6.0 7.9 2.5 6.0 4.9 1.5 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B Myosin_tail_1 PF01576.14 CDJ63449.1 - 2.5 5.6 27.8 40 1.7 19.3 2.0 1 1 0 1 1 1 0 Myosin tail Bap31 PF05529.7 CDJ63449.1 - 2.6 7.4 13.4 0.44 9.9 3.5 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like TMF_TATA_bd PF12325.3 CDJ63449.1 - 2.6 7.7 25.7 0.17 11.6 4.6 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FemAB PF02388.11 CDJ63449.1 - 2.9 6.5 9.2 1.4 7.5 4.7 1.5 1 1 0 1 1 1 0 FemAB family U1snRNP70_N PF12220.3 CDJ63449.1 - 2.9 8.2 8.3 0.48 10.7 2.6 2.0 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rotamase PF00639.16 CDJ63449.1 - 3.1 8.6 6.4 5.6 7.7 3.0 2.2 1 1 2 3 3 2 0 PPIC-type PPIASE domain IncA PF04156.9 CDJ63449.1 - 3.7 7.1 28.6 0.065 12.8 10.0 2.1 1 1 1 2 2 2 0 IncA protein TMCO5 PF14992.1 CDJ63449.1 - 3.9 6.5 17.9 9.3 5.2 12.4 1.5 1 1 0 1 1 1 0 TMCO5 family TMPIT PF07851.8 CDJ63449.1 - 4.6 6.2 10.9 1.6 7.7 4.0 1.9 1 1 1 2 2 2 0 TMPIT-like protein FUSC PF04632.7 CDJ63449.1 - 4.6 5.5 5.3 5.6 5.2 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prefoldin PF02996.12 CDJ63449.1 - 5.4 6.6 16.5 3.2 7.4 1.6 3.2 1 1 2 3 3 3 0 Prefoldin subunit OmpH PF03938.9 CDJ63449.1 - 6.2 6.7 21.6 1.8 8.4 12.6 1.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.10 CDJ63449.1 - 7.4 5.6 15.2 15 4.6 10.6 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 CDJ63449.1 - 8.1 4.7 14.5 6.3 5.0 5.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 CDJ63449.1 - 9.5 6.3 13.0 5.1 7.2 6.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cation_efflux PF01545.16 CDJ63450.1 - 9.3e-59 198.8 8.2 1.2e-58 198.4 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1180 PF06679.7 CDJ63451.1 - 0.0023 17.8 0.1 0.0045 16.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Virul_fac_BrkB PF03631.10 CDJ63451.1 - 0.065 12.5 0.1 0.33 10.2 0.1 1.9 2 0 0 2 2 2 0 Virulence factor BrkB DNA_pol_A_exo1 PF01612.15 CDJ63452.1 - 5.9e-35 120.3 0.0 1.2e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 CDJ63452.1 - 7e-12 44.8 0.1 1.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain RNase_T PF00929.19 CDJ63453.1 - 5.9e-26 91.7 0.0 6.8e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Exonuclease eIF2A PF08662.6 CDJ63454.1 - 1.1e-38 132.9 0.0 7e-31 107.4 0.0 3.5 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Chromo PF00385.19 CDJ63455.1 - 1.9e-13 49.8 0.0 4.2e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cyclin PF08613.6 CDJ63458.1 - 7.2e-31 107.6 0.2 7.2e-31 107.6 0.1 4.1 3 2 0 3 3 3 1 Cyclin Cyclin_N PF00134.18 CDJ63458.1 - 5.4e-06 25.9 0.1 5.4e-06 25.9 0.1 5.7 5 4 0 5 5 5 1 Cyclin, N-terminal domain SR-25 PF10500.4 CDJ63460.1 - 5.1e-05 22.8 22.4 5.5e-05 22.7 15.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ63460.1 - 0.0026 16.8 9.1 0.0028 16.7 6.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein SAGA-Tad1 PF12767.2 CDJ63460.1 - 0.0099 15.5 10.0 0.0099 15.5 6.9 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Cwf_Cwc_15 PF04889.7 CDJ63460.1 - 0.015 14.9 7.9 0.017 14.8 5.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med15 PF09606.5 CDJ63460.1 - 0.071 11.3 31.3 0.075 11.2 21.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CobT PF06213.7 CDJ63460.1 - 0.12 11.4 7.6 0.13 11.4 5.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spt20 PF12090.3 CDJ63460.1 - 0.18 11.1 7.7 0.19 11.0 5.4 1.3 1 0 0 1 1 1 0 Spt20 family FHIPEP PF00771.15 CDJ63460.1 - 0.19 10.0 4.1 0.19 9.9 2.9 1.0 1 0 0 1 1 1 0 FHIPEP family DUF2215 PF10225.4 CDJ63460.1 - 0.24 10.8 5.2 0.23 10.8 3.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FAM60A PF15396.1 CDJ63460.1 - 0.32 10.7 10.8 0.34 10.6 7.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF755 PF05501.6 CDJ63460.1 - 0.32 11.0 33.5 0.51 10.4 23.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) FLO_LFY PF01698.11 CDJ63460.1 - 0.49 9.1 5.2 0.54 9.0 3.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein UPF0560 PF10577.4 CDJ63460.1 - 0.78 7.9 18.4 0.77 7.9 12.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DDHD PF02862.12 CDJ63460.1 - 0.81 9.4 11.3 0.78 9.4 7.8 1.1 1 0 0 1 1 1 0 DDHD domain Plasmodium_Vir PF05795.6 CDJ63460.1 - 0.85 8.7 8.6 0.86 8.7 6.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4557 PF15101.1 CDJ63460.1 - 0.94 9.2 17.1 1 9.1 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Nha1_C PF08619.5 CDJ63460.1 - 1.7 7.8 17.5 1.9 7.6 12.1 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2217 PF10265.4 CDJ63460.1 - 1.7 7.2 13.8 1.8 7.2 9.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Suf PF05843.9 CDJ63460.1 - 1.8 8.1 12.4 1.9 8.1 8.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 CDJ63460.1 - 2.1 8.1 6.1 2 8.2 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.12 CDJ63460.1 - 2.3 6.9 11.9 2.3 6.9 8.3 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.10 CDJ63460.1 - 2.5 6.7 6.8 2.6 6.6 4.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) vMSA PF00695.14 CDJ63460.1 - 2.7 7.0 8.8 3.1 6.9 6.1 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF2967 PF11179.3 CDJ63460.1 - 3 7.2 29.4 3.7 6.9 20.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RR_TM4-6 PF06459.7 CDJ63460.1 - 3.7 7.3 8.8 3.7 7.3 6.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDJ63460.1 - 3.8 5.0 13.0 3.8 5.0 9.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Conotoxin PF02950.12 CDJ63460.1 - 5 8.0 6.7 12 6.8 4.6 1.7 1 0 0 1 1 1 0 Conotoxin Macoilin PF09726.4 CDJ63460.1 - 5.5 5.1 17.9 5.8 5.0 12.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 CDJ63460.1 - 6.1 5.7 15.0 5.9 5.8 10.4 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF788 PF05620.6 CDJ63460.1 - 6.3 6.6 7.7 9.4 6.0 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) NPR3 PF03666.8 CDJ63460.1 - 8.2 4.8 13.4 8.7 4.7 9.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Med15 PF09606.5 CDJ63462.1 - 2.5e-05 22.7 35.7 3e-05 22.4 24.7 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Bac_DNA_binding PF00216.16 CDJ63462.1 - 0.011 15.7 0.5 0.032 14.2 0.1 1.9 1 1 1 2 2 2 0 Bacterial DNA-binding protein HTH_IclR PF09339.5 CDJ63462.1 - 0.019 14.5 0.5 0.019 14.5 0.3 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF2422 PF10337.4 CDJ63462.1 - 0.048 12.4 10.4 0.055 12.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) PAT1 PF09770.4 CDJ63462.1 - 3 5.9 33.9 3.4 5.7 23.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3573 PF12097.3 CDJ63462.1 - 4.3 5.8 5.5 5.6 5.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Med15 PF09606.5 CDJ63463.1 - 0.0021 16.3 73.2 0.0023 16.2 50.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ63463.1 - 0.021 13.1 59.2 0.021 13.1 41.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MDM1 PF15501.1 CDJ63463.1 - 0.023 13.6 38.6 0.029 13.3 26.7 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 Ribosomal_60s PF00428.14 CDJ63463.1 - 0.043 14.1 2.4 0.083 13.2 1.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein MRP-S31 PF15433.1 CDJ63463.1 - 0.48 9.8 31.2 0.6 9.4 21.6 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 RR_TM4-6 PF06459.7 CDJ63463.1 - 0.48 10.2 24.7 0.64 9.8 17.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 CDJ63463.1 - 0.64 7.6 24.2 0.66 7.6 16.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF342 PF03961.8 CDJ63463.1 - 0.65 8.3 13.4 0.71 8.2 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Parvo_coat PF00740.13 CDJ63463.1 - 1.2 7.9 30.7 1.4 7.7 21.3 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 GAGA_bind PF06217.7 CDJ63463.1 - 1.8 8.4 29.0 2.2 8.1 20.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 CDJ63463.1 - 2.2 7.0 27.7 2.8 6.6 19.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Pilt PF15453.1 CDJ63463.1 - 2.3 7.7 38.3 3.1 7.4 26.6 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Herpes_UL87 PF03043.9 CDJ63463.1 - 2.9 6.1 15.4 3.3 6.0 10.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Filo_glycop PF01611.11 CDJ63463.1 - 3 6.5 17.3 2.9 6.5 12.0 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein eIF-3_zeta PF05091.7 CDJ63463.1 - 3.6 6.1 35.2 4.2 5.8 24.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1510 PF07423.6 CDJ63463.1 - 5.8 6.2 32.7 10 5.4 22.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDK2AP PF09806.4 CDJ63464.1 - 1.4 9.0 6.0 1.5 9.0 4.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4139 PF13598.1 CDJ63464.1 - 5.2 6.2 7.6 6 6.0 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) AFT PF08731.6 CDJ63466.1 - 0.017 15.3 0.7 0.025 14.7 0.5 1.2 1 0 0 1 1 1 0 Transcription factor AFT DUF3512 PF12024.3 CDJ63466.1 - 0.035 13.4 0.1 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) TFIIA PF03153.8 CDJ63466.1 - 0.053 13.4 6.0 0.058 13.2 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 CDJ63466.1 - 0.88 8.7 28.0 0.13 11.4 7.0 2.0 1 1 0 2 2 2 0 Mediator complex subunit 3 fungal FKBP_N PF01346.13 CDJ63466.1 - 0.95 9.5 12.3 0.99 9.4 0.2 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TetR_C PF02909.12 CDJ63466.1 - 2.5 7.7 6.1 1.6 8.3 0.4 2.1 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain DivIC PF04977.10 CDJ63466.1 - 5.7 6.5 9.8 0.55 9.7 3.4 1.8 2 0 0 2 2 2 0 Septum formation initiator PHD_3 PF13922.1 CDJ63466.1 - 7.9 6.8 8.7 1.9 8.8 3.7 1.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Ycf66_N PF07444.6 CDJ63467.1 - 0.06 13.0 0.6 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 Ycf66 protein N-terminus ERM PF00769.14 CDJ63467.1 - 0.21 11.1 1.0 0.3 10.5 0.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FHIPEP PF00771.15 CDJ63468.1 - 0.19 10.0 1.2 0.25 9.6 0.8 1.1 1 0 0 1 1 1 0 FHIPEP family S1-P1_nuclease PF02265.11 CDJ63470.1 - 7e-25 88.1 1.9 7e-25 88.1 1.3 2.3 1 1 1 2 2 2 1 S1/P1 Nuclease PRCC PF10253.4 CDJ63470.1 - 0.00027 21.6 14.8 0.00027 21.6 10.3 3.4 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DUF605 PF04652.11 CDJ63470.1 - 0.00029 20.3 16.3 0.00029 20.3 11.3 3.5 2 1 1 3 3 3 1 Vta1 like Spore_coat_CotO PF14153.1 CDJ63470.1 - 0.0013 18.2 3.8 0.0013 18.2 2.6 2.7 2 1 0 2 2 2 1 Spore coat protein CotO SR-25 PF10500.4 CDJ63470.1 - 0.003 17.0 11.1 0.003 17.0 7.7 3.1 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein DUF4557 PF15101.1 CDJ63470.1 - 0.015 15.1 12.0 0.015 15.1 8.3 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4557) Ycf1 PF05758.7 CDJ63470.1 - 0.028 12.1 16.8 0.37 8.4 0.2 2.1 2 0 0 2 2 2 0 Ycf1 Hid1 PF12722.2 CDJ63470.1 - 2.8 5.5 33.7 0.14 9.8 2.9 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PBP1_TM PF14812.1 CDJ63470.1 - 5.2 7.4 9.3 0.59 10.4 0.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal THRAP3_BCLAF1 PF15440.1 CDJ63471.1 - 2.8 6.4 68.0 3.6 6.1 47.1 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF236 PF03057.9 CDJ63472.1 - 0.46 10.4 4.4 1.4 8.9 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function LZ_Tnp_IS66 PF13007.2 CDJ63472.1 - 6.9 7.4 6.5 8.9 7.0 4.5 1.3 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain Aminotran_5 PF00266.14 CDJ63473.1 - 8.2e-06 24.7 0.0 1.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Spt20 PF12090.3 CDJ63473.1 - 0.015 14.6 0.3 0.015 14.6 0.2 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDJ63473.1 - 0.038 13.7 1.7 0.035 13.8 1.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Caudo_TAP PF02413.12 CDJ63473.1 - 0.049 13.7 5.3 0.08 13.1 3.6 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Med3 PF11593.3 CDJ63473.1 - 0.13 11.4 6.7 0.18 11.0 4.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med15 PF09606.5 CDJ63473.1 - 0.29 9.3 16.5 0.35 9.0 11.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3682 PF12446.3 CDJ63473.1 - 6.4 7.0 11.8 9.4 6.5 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) SAGA-Tad1 PF12767.2 CDJ63474.1 - 0.011 15.4 5.8 0.013 15.2 4.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF605 PF04652.11 CDJ63474.1 - 0.023 14.1 8.1 0.025 13.9 5.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF4366 PF14283.1 CDJ63474.1 - 0.16 11.3 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) PP2C_2 PF13672.1 CDJ63474.1 - 0.83 9.0 6.1 1.6 8.1 4.2 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C TFIIA PF03153.8 CDJ63474.1 - 0.94 9.3 18.1 1.2 8.9 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ63474.1 - 1 7.5 22.2 1.1 7.3 15.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ctr PF04145.10 CDJ63474.1 - 1.1 9.2 2.8 2.2 8.3 2.0 1.4 1 0 0 1 1 1 0 Ctr copper transporter family RIC3 PF15361.1 CDJ63474.1 - 1.3 9.2 7.6 3.2 7.9 5.3 1.7 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GSK-3_bind PF05350.7 CDJ63474.1 - 2.9 7.2 14.0 4.8 6.5 9.7 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding DUF4175 PF13779.1 CDJ63474.1 - 7.4 4.1 24.7 12 3.4 17.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GHMP_kinases_N PF00288.21 CDJ63475.1 - 0.00021 21.3 0.0 0.00021 21.3 0.0 10.1 9 3 2 11 11 11 1 GHMP kinases N terminal domain Activator_LAG-3 PF11498.3 CDJ63475.1 - 0.22 10.2 75.4 0.49 9.0 0.7 3.6 3 0 0 3 3 3 0 Transcriptional activator LAG-3 SID-1_RNA_chan PF13965.1 CDJ63475.1 - 0.32 9.0 3.2 0.54 8.3 2.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4647 PF15504.1 CDJ63475.1 - 1 8.1 22.8 1 8.1 11.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) AAA_23 PF13476.1 CDJ63475.1 - 1.5 9.1 16.4 0.83 9.9 8.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3801 PF12687.2 CDJ63475.1 - 6.4 6.2 22.2 1.2 8.7 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) NPR3 PF03666.8 CDJ63476.1 - 0.36 9.3 2.8 0.57 8.6 1.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.10 CDJ63476.1 - 1.4 7.5 4.0 1.3 7.5 2.8 1.2 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.4 CDJ63476.1 - 3.5 6.3 14.9 5.8 5.6 10.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAP65_ASE1 PF03999.7 CDJ63476.1 - 5.9 5.3 13.8 7.2 5.0 9.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Sec3_C PF09763.4 CDJ63476.1 - 9 4.2 7.3 11 3.9 5.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 AroM PF07302.6 CDJ63477.1 - 0.0068 15.7 0.9 0.0068 15.7 0.6 2.1 2 0 0 2 2 1 1 AroM protein DUF755 PF05501.6 CDJ63477.1 - 0.012 15.6 7.9 0.012 15.6 5.5 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF755) DUF912 PF06024.7 CDJ63477.1 - 0.019 15.0 1.9 0.019 15.0 1.3 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CDJ63477.1 - 0.02 13.9 27.0 0.19 10.7 13.6 2.1 2 0 0 2 2 2 0 Fms-interacting protein Cas_Cmr3 PF09700.5 CDJ63477.1 - 0.12 11.7 3.5 0.047 13.1 0.6 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr3) Peptidase_U57 PF05582.7 CDJ63477.1 - 0.21 10.5 9.7 0.11 11.4 3.4 2.0 2 0 0 2 2 2 0 YabG peptidase U57 TFIIA PF03153.8 CDJ63477.1 - 0.28 11.0 42.7 0.39 10.5 29.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OATP PF03137.15 CDJ63477.1 - 0.38 8.7 10.7 0.05 11.6 2.0 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3371 PF11851.3 CDJ63477.1 - 0.38 11.4 28.4 0.3 11.7 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Rxt3 PF08642.5 CDJ63477.1 - 0.42 10.8 6.4 0.86 9.8 1.4 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Usp PF00582.21 CDJ63477.1 - 0.55 10.4 12.3 3.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Universal stress protein family Dala_Dala_lig_N PF01820.16 CDJ63477.1 - 0.83 9.9 7.0 0.64 10.3 2.0 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF2361 PF10153.4 CDJ63477.1 - 1.1 9.4 14.7 2 8.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) DUF1681 PF07933.9 CDJ63477.1 - 1.1 8.7 7.1 0.27 10.7 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) DUF2232 PF09991.4 CDJ63477.1 - 1.4 7.8 7.2 0.15 11.0 1.7 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) ARGLU PF15346.1 CDJ63477.1 - 1.5 8.5 24.2 0.59 9.8 10.5 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF4011 PF13195.1 CDJ63477.1 - 1.6 8.7 10.6 1.3 8.9 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DUF1764 PF08576.5 CDJ63477.1 - 2 9.2 18.9 3.8 8.3 7.3 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Herpes_UL87 PF03043.9 CDJ63477.1 - 2 6.6 13.4 2.7 6.2 9.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family PBP1_TM PF14812.1 CDJ63477.1 - 3.2 8.1 5.4 0.59 10.4 0.7 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1980 PF09323.5 CDJ63477.1 - 4 7.1 8.6 0.89 9.2 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) HA2 PF04408.18 CDJ63477.1 - 5.2 7.1 10.2 10 6.1 2.8 2.4 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF4446 PF14584.1 CDJ63477.1 - 6.4 6.5 8.6 1.8 8.3 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Glt_symporter PF03616.9 CDJ63477.1 - 6.5 5.1 7.2 0.77 8.1 2.2 1.5 2 0 0 2 2 2 0 Sodium/glutamate symporter Folate_carrier PF01770.13 CDJ63477.1 - 9.2 4.6 9.0 0.78 8.1 1.7 2.0 2 0 0 2 2 2 0 Reduced folate carrier DUF4638 PF15472.1 CDJ63477.1 - 9.3 5.7 14.0 9.6 5.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) Spore_coat_CotO PF14153.1 CDJ63477.1 - 9.6 5.6 23.7 2.1 7.7 10.4 2.2 2 0 0 2 2 2 0 Spore coat protein CotO FNIP_N PF14636.1 CDJ63478.1 - 0.002 18.5 2.1 0.0026 18.2 1.4 1.2 1 0 0 1 1 1 1 Folliculin-interacting protein N-terminus SR-25 PF10500.4 CDJ63478.1 - 0.021 14.2 1.5 0.029 13.8 1.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CtsR PF05848.6 CDJ63478.1 - 0.49 10.3 6.8 0.63 10.0 4.7 1.1 1 0 0 1 1 1 0 Firmicute transcriptional repressor of class III stress genes (CtsR) DUF572 PF04502.8 CDJ63478.1 - 0.64 9.1 9.5 0.72 9.0 6.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) HD_assoc PF13286.1 CDJ63478.1 - 0.73 10.1 8.9 1.1 9.5 6.1 1.4 1 0 0 1 1 1 0 Phosphohydrolase-associated domain DUF2361 PF10153.4 CDJ63478.1 - 0.74 10.0 13.3 0.99 9.6 9.2 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) eIF3_subunit PF08597.5 CDJ63478.1 - 2.1 7.8 10.0 2.7 7.4 7.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CCG PF02754.11 CDJ63478.1 - 2.8 7.9 5.7 0.37 10.8 0.9 1.8 2 1 0 2 2 2 0 Cysteine-rich domain PAT1 PF09770.4 CDJ63478.1 - 3.4 5.7 29.3 3.6 5.7 20.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S49_N PF08496.5 CDJ63478.1 - 3.9 7.2 7.9 5.2 6.8 5.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Thioredoxin_4 PF13462.1 CDJ63478.1 - 4 7.4 8.2 4.9 7.1 5.7 1.1 1 0 0 1 1 1 0 Thioredoxin Peptidase_S15 PF02129.13 CDJ63478.1 - 6.3 6.1 9.0 7.1 5.9 6.2 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Band_3_cyto PF07565.8 CDJ63478.1 - 7.1 6.0 10.1 8 5.8 7.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Med15 PF09606.5 CDJ63478.1 - 9.7 4.2 48.4 11 4.0 33.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3088 PF11287.3 CDJ63479.1 - 0.059 12.8 0.4 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) Mac PF12464.3 CDJ63479.1 - 0.14 12.1 1.3 12 5.9 0.2 2.8 2 1 0 2 2 2 0 Maltose acetyltransferase Couple_hipA PF13657.1 CDJ63479.1 - 0.2 11.9 5.0 0.1 12.9 1.5 2.0 2 1 0 2 2 2 0 HipA N-terminal domain DUF3726 PF12525.3 CDJ63479.1 - 0.72 9.6 4.9 0.38 10.5 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3726) Macoilin PF09726.4 CDJ63479.1 - 1.2 7.3 11.9 3 5.9 8.3 1.6 1 1 0 1 1 1 0 Transmembrane protein Rhodanese PF00581.15 CDJ63480.1 - 8e-05 22.9 0.3 0.0009 19.5 0.0 2.9 2 0 0 2 2 2 1 Rhodanese-like domain Med15 PF09606.5 CDJ63480.1 - 0.15 10.2 131.3 0.16 10.1 29.8 3.5 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal DnaJ PF00226.26 CDJ63481.1 - 2e-10 40.2 0.1 4.8e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain PrgI PF12666.2 CDJ63481.1 - 7.1 6.8 6.3 22 5.2 2.8 2.7 1 1 1 2 2 2 0 PrgI family protein BPD_transp_2 PF02653.11 CDJ63482.1 - 0.019 13.9 0.9 0.035 13.0 0.6 1.5 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Ribosomal_60s PF00428.14 CDJ63482.1 - 0.31 11.4 30.8 0.065 13.6 4.5 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein UPF0565 PF10561.4 CDJ63482.1 - 2.9 6.6 4.8 3.5 6.4 2.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0565 Cwf_Cwc_15 PF04889.7 CDJ63483.1 - 0.04 13.6 0.1 0.04 13.6 0.1 4.0 2 1 1 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF3357 PF11837.3 CDJ63484.1 - 1.2 9.0 9.4 2.3 8.0 0.7 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF3357) Claudin_2 PF13903.1 CDJ63484.1 - 1.9 8.1 17.7 1.5 8.5 4.0 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DEAD PF00270.24 CDJ63485.1 - 4.8e-26 91.2 0.0 7.9e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ63485.1 - 6.3e-18 64.4 0.1 2e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.23 CDJ63485.1 - 0.039 14.0 0.1 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 SPRY domain APC_CDC26 PF10471.4 CDJ63485.1 - 0.063 14.0 3.3 0.13 12.9 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Sporozoite_P67 PF05642.6 CDJ63485.1 - 0.52 8.1 5.0 0.92 7.2 3.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Acyltransferase PF01553.16 CDJ63486.1 - 1.1e-14 53.9 0.0 3e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase PIH1 PF08190.7 CDJ63487.1 - 0.0007 19.1 1.5 0.0007 19.1 1.0 7.2 2 2 2 6 6 6 2 pre-RNA processing PIH1/Nop17 TRAPPC9-Trs120 PF08626.6 CDJ63490.1 - 1.1e-06 26.3 2.2 9e-06 23.3 0.3 2.6 3 0 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GTP_EFTU PF00009.22 CDJ63491.1 - 7.9e-56 188.4 0.0 1.2e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CDJ63491.1 - 1.4e-35 121.3 0.1 5.6e-35 119.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CDJ63491.1 - 1.5e-17 63.4 0.4 4.7e-17 61.8 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CDJ63491.1 - 1.2e-05 24.8 0.8 3.4e-05 23.4 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CDJ63491.1 - 0.00068 19.5 0.0 0.0024 17.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NIF3 PF01784.13 CDJ63491.1 - 0.0028 17.2 0.6 0.0055 16.3 0.0 1.7 2 0 0 2 2 2 1 NIF3 (NGG1p interacting factor 3) G-alpha PF00503.15 CDJ63491.1 - 0.059 12.0 1.0 0.1 11.2 0.7 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF3328 PF11807.3 CDJ63493.1 - 0.013 15.1 0.2 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Peptidase_C6 PF00851.13 CDJ63493.1 - 1.2 7.7 5.4 1.9 7.0 3.7 1.2 1 0 0 1 1 1 0 Helper component proteinase PAT1 PF09770.4 CDJ63494.1 - 0.0026 16.0 31.6 0.0026 16.1 21.9 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDJ63494.1 - 0.0048 15.1 20.1 0.0052 15.0 13.9 1.1 1 0 0 1 1 1 1 Utp14 protein DDRGK PF09756.4 CDJ63494.1 - 0.056 12.8 25.7 0.074 12.4 17.8 1.1 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.9 CDJ63494.1 - 0.13 10.2 15.5 0.15 10.0 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 CDJ63494.1 - 0.19 10.3 14.6 0.2 10.2 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDJ63494.1 - 0.2 9.3 15.5 0.23 9.1 10.8 1.0 1 0 0 1 1 1 0 Ycf1 Dicty_REP PF05086.7 CDJ63494.1 - 0.23 9.1 9.9 0.24 9.1 6.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.2 CDJ63494.1 - 0.24 9.0 20.4 0.26 8.9 14.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FHIPEP PF00771.15 CDJ63494.1 - 0.29 9.4 6.9 0.43 8.8 4.8 1.3 1 0 0 1 1 1 0 FHIPEP family LMBR1 PF04791.11 CDJ63494.1 - 0.37 9.3 4.7 0.37 9.3 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Cwf_Cwc_15 PF04889.7 CDJ63494.1 - 1.2 8.8 25.7 2 8.0 17.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FimP PF09766.4 CDJ63494.1 - 1.2 8.1 25.9 1.9 7.4 18.0 1.4 1 0 0 1 1 1 0 Fms-interacting protein DUF3513 PF12026.3 CDJ63494.1 - 1.6 8.2 28.7 0.97 8.9 18.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3513) Otopetrin PF03189.8 CDJ63494.1 - 2.9 6.7 7.2 3.1 6.6 5.0 1.1 1 0 0 1 1 1 0 Otopetrin Tim54 PF11711.3 CDJ63494.1 - 3.2 6.2 12.8 4.3 5.8 8.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HlyD_2 PF12700.2 CDJ63494.1 - 3.6 6.6 15.3 4 6.5 10.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Cellulose_synt PF03552.9 CDJ63494.1 - 4.6 5.4 6.6 5.6 5.1 4.6 1.1 1 0 0 1 1 1 0 Cellulose synthase Mem_trans PF03547.13 CDJ63494.1 - 4.6 5.4 13.3 6 5.0 9.2 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF853 PF05872.7 CDJ63494.1 - 4.7 5.4 14.6 7.1 4.8 10.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2052 PF09747.4 CDJ63494.1 - 4.8 7.0 24.3 8.6 6.2 16.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4175 PF13779.1 CDJ63494.1 - 5.9 4.4 44.7 8.1 4.0 31.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ebola_NP PF05505.7 CDJ63494.1 - 7.7 4.4 18.7 9.7 4.1 12.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Med15 PF09606.5 CDJ63494.1 - 8.2 4.4 51.3 0.047 11.8 29.9 1.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDJ63494.1 - 9 4.9 43.3 16 4.0 30.0 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Bud13 PF09736.4 CDJ63494.1 - 9.8 6.4 24.2 15 5.7 16.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex SR-25 PF10500.4 CDJ63495.1 - 0.0027 17.2 16.3 0.0027 17.2 11.3 2.5 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Presenilin PF01080.12 CDJ63495.1 - 1.1 7.9 6.6 2.5 6.8 4.6 1.5 1 0 0 1 1 1 0 Presenilin Suf PF05843.9 CDJ63495.1 - 1.6 8.4 10.5 2.8 7.5 7.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GAGA_bind PF06217.7 CDJ63495.1 - 2 8.3 8.7 1.2 9.0 4.7 1.5 2 0 0 2 2 2 0 GAGA binding protein-like family eIF-3_zeta PF05091.7 CDJ63495.1 - 4 5.9 11.9 5.8 5.4 8.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Mnd1 PF03962.10 CDJ63495.1 - 8 6.0 15.2 16 5.1 10.5 1.4 1 0 0 1 1 1 0 Mnd1 family AAA_23 PF13476.1 CDJ63495.1 - 8.2 6.6 11.5 14 5.9 8.0 1.4 1 0 0 1 1 1 0 AAA domain Enkurin PF13864.1 CDJ63496.1 - 1.6e-05 25.0 7.6 1.6e-05 25.0 5.3 1.8 2 1 1 3 3 3 1 Calmodulin-binding Collagen PF01391.13 CDJ63496.1 - 3 7.4 111.3 0.2 11.2 26.3 5.1 2 2 1 3 3 3 0 Collagen triple helix repeat (20 copies) Abhydrolase_1 PF00561.15 CDJ63497.1 - 2.4e-11 43.6 0.0 3e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDJ63497.1 - 1.1e-09 38.4 1.1 1.1e-09 38.4 0.8 2.9 2 2 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.9 CDJ63497.1 - 0.019 13.4 0.0 0.032 12.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family Zip PF02535.17 CDJ63497.1 - 3 6.7 11.6 6.5 5.6 8.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Rad51 PF08423.6 CDJ63498.1 - 1.9e-11 43.3 1.3 1.3e-07 30.7 1.1 3.6 2 1 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CDJ63498.1 - 9.8e-11 41.4 0.1 9.8e-11 41.4 0.0 3.4 4 0 0 4 4 4 1 AAA domain RecA PF00154.16 CDJ63498.1 - 1.1e-06 28.0 0.3 0.0008 18.5 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 CDJ63498.1 - 0.0009 18.4 0.0 0.014 14.5 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 CDJ63498.1 - 0.0014 18.8 0.1 0.37 10.9 0.1 3.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CDJ63498.1 - 0.002 17.7 3.3 0.056 13.1 2.3 2.5 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 CDJ63498.1 - 0.017 14.9 10.2 0.42 10.4 0.1 4.2 3 2 1 4 4 4 0 AAA domain SMC_N PF02463.14 CDJ63498.1 - 0.092 11.9 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zn_peptidase PF04228.8 CDJ63499.1 - 0.26 10.4 14.8 0.013 14.7 6.5 1.5 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Ribosomal_60s PF00428.14 CDJ63499.1 - 6.6 7.2 8.6 12 6.3 5.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.3 CDJ63501.1 - 0.2 10.9 5.8 0.2 10.9 4.0 1.0 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDJ63501.1 - 0.25 10.3 7.4 0.25 10.3 5.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein CobU PF02283.11 CDJ63501.1 - 0.47 9.8 2.6 0.5 9.7 1.8 1.0 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Med15 PF09606.5 CDJ63501.1 - 1.4 7.0 17.2 1.2 7.2 11.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF945 PF06097.6 CDJ63501.1 - 3.4 6.3 7.7 3.7 6.2 5.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) DUF3371 PF11851.3 CDJ63501.1 - 3.5 8.3 8.5 3.5 8.3 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) RED_N PF07808.8 CDJ63501.1 - 6.6 5.8 8.1 6.3 5.9 5.6 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Pex14_N PF04695.8 CDJ63502.1 - 0.002 18.1 1.2 0.002 18.1 0.8 22.5 8 4 8 16 16 16 1 Peroxisomal membrane anchor protein (Pex14p) conserved region OMPdecase PF00215.19 CDJ63503.1 - 2.8e-08 33.4 10.2 2.1e-07 30.6 7.1 2.1 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Chorion_2 PF03964.10 CDJ63504.1 - 0.044 14.3 0.5 0.085 13.4 0.1 1.7 2 0 0 2 2 2 0 Chorion family 2 Proteasome PF00227.21 CDJ63505.1 - 2.6e-17 62.7 0.0 3.1e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TFIIA PF03153.8 CDJ63507.1 - 8.5 6.1 27.3 11 5.7 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WES_acyltransf PF03007.11 CDJ63507.1 - 9.6 5.6 13.2 15 5.0 9.1 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain IncA PF04156.9 CDJ63508.1 - 2.9e-06 27.0 15.6 2.9e-06 27.0 10.8 1.4 2 0 0 2 2 1 1 IncA protein Med15 PF09606.5 CDJ63508.1 - 0.0002 19.7 40.7 0.00024 19.4 28.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4131 PF13567.1 CDJ63508.1 - 0.0014 18.0 4.4 0.0018 17.7 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) PAT1 PF09770.4 CDJ63508.1 - 0.0031 15.8 33.0 0.003 15.9 22.9 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDJ63508.1 - 0.0045 16.3 37.6 0.0064 15.8 26.0 1.1 1 0 0 1 1 1 1 SprA-related family AAA_23 PF13476.1 CDJ63508.1 - 0.0052 17.1 10.6 0.0052 17.1 7.3 1.2 1 0 0 1 1 1 1 AAA domain FHIPEP PF00771.15 CDJ63508.1 - 0.0055 15.0 7.9 0.009 14.4 5.5 1.3 1 0 0 1 1 1 1 FHIPEP family Suf PF05843.9 CDJ63508.1 - 0.0059 16.3 15.0 0.0068 16.1 10.4 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Serinc PF03348.10 CDJ63508.1 - 0.0074 15.0 11.4 0.0081 14.9 7.9 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Herpes_glycop PF01528.11 CDJ63508.1 - 0.012 14.3 4.6 0.014 14.1 3.2 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Apt1 PF10351.4 CDJ63508.1 - 0.015 14.2 7.9 0.018 13.9 5.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain FLO_LFY PF01698.11 CDJ63508.1 - 0.03 13.1 10.0 0.033 13.0 6.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 CDJ63508.1 - 0.039 11.6 10.5 0.04 11.6 7.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S49_N PF08496.5 CDJ63508.1 - 0.059 13.1 11.8 0.08 12.7 8.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FPN1 PF06963.7 CDJ63508.1 - 0.059 11.7 5.9 0.08 11.3 4.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) SID-1_RNA_chan PF13965.1 CDJ63508.1 - 0.066 11.3 7.1 0.07 11.2 4.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4557 PF15101.1 CDJ63508.1 - 0.082 12.7 23.9 0.11 12.2 16.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3007 PF11460.3 CDJ63508.1 - 0.1 12.6 9.6 0.15 12.1 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) OATP PF03137.15 CDJ63508.1 - 0.19 9.7 8.3 0.25 9.3 5.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.13 CDJ63508.1 - 0.2 10.1 7.8 0.25 9.8 5.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.7 CDJ63508.1 - 0.21 11.4 11.6 0.24 11.2 8.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dala_Dala_lig_N PF01820.16 CDJ63508.1 - 0.3 11.3 9.6 0.51 10.6 6.7 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FimP PF09766.4 CDJ63508.1 - 0.38 9.7 27.4 0.56 9.2 19.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF4446 PF14584.1 CDJ63508.1 - 0.44 10.3 8.3 0.69 9.7 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Nucleoside_tran PF01733.13 CDJ63508.1 - 0.44 9.6 3.6 0.54 9.3 2.5 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF2232 PF09991.4 CDJ63508.1 - 0.56 9.1 7.2 0.8 8.6 5.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) eIF-3_zeta PF05091.7 CDJ63508.1 - 0.64 8.5 19.2 0.74 8.3 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3408 PF11888.3 CDJ63508.1 - 0.64 9.9 13.9 1 9.3 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Ycf1 PF05758.7 CDJ63508.1 - 0.68 7.5 12.6 0.78 7.3 8.7 1.1 1 0 0 1 1 1 0 Ycf1 Pex16 PF08610.5 CDJ63508.1 - 0.77 8.6 14.7 1.2 8.0 10.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3260 PF11658.3 CDJ63508.1 - 0.78 7.8 12.6 0.91 7.5 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Peptidase_C37 PF05416.7 CDJ63508.1 - 0.95 7.6 8.8 0.93 7.7 6.1 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase AAT PF03417.11 CDJ63508.1 - 1.2 8.5 12.2 1.6 8.1 8.4 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase EIIBC-GUT_N PF03612.9 CDJ63508.1 - 2 7.9 10.5 2.8 7.5 7.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus HemX PF04375.9 CDJ63508.1 - 2.2 6.7 34.5 3 6.3 23.9 1.1 1 0 0 1 1 1 0 HemX TFIIA PF03153.8 CDJ63508.1 - 2.3 8.0 34.2 2.8 7.7 23.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.1 CDJ63508.1 - 2.4 7.5 23.7 3.4 7.0 16.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Peptidase_S15 PF02129.13 CDJ63508.1 - 2.9 7.2 17.3 3.8 6.8 12.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Paramyxo_ncap PF00973.14 CDJ63508.1 - 2.9 6.4 13.1 3.5 6.2 9.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HCO3_cotransp PF00955.16 CDJ63508.1 - 3 6.4 6.7 4.1 5.9 4.6 1.2 1 0 0 1 1 1 0 HCO3- transporter family Hom_end_hint PF05203.11 CDJ63508.1 - 5.2 6.7 11.8 6.9 6.3 8.2 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Cellulose_synt PF03552.9 CDJ63508.1 - 6.2 4.9 6.7 7 4.8 4.6 1.1 1 0 0 1 1 1 0 Cellulose synthase SR-25 PF10500.4 CDJ63508.1 - 6.2 6.2 28.2 1.3 8.4 6.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Oleosin PF01277.12 CDJ63508.1 - 8.4 5.9 17.5 1.3e+02 2.2 12.1 2.1 1 1 0 1 1 1 0 Oleosin Peptidase_U57 PF05582.7 CDJ63508.1 - 9.4 5.1 13.7 13 4.6 9.5 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DcuC PF03606.10 CDJ63508.1 - 9.5 4.3 10.6 17 3.5 7.4 1.4 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier rve PF00665.21 CDJ63509.1 - 4.2e-10 39.7 0.0 8.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDJ63509.1 - 7e-09 35.2 0.0 1.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDJ63510.1 - 2.4e-06 27.0 0.0 4.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDJ63510.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 RNase H DEAD PF00270.24 CDJ63514.1 - 2.2e-42 144.3 0.1 3.1e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ63514.1 - 1.1e-25 89.2 0.1 2e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CDJ63514.1 - 0.055 12.5 0.1 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MMR_HSR1 PF01926.18 CDJ63515.1 - 7.7e-38 129.0 0.0 7.2e-20 71.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 CDJ63515.1 - 6.2e-24 83.7 0.0 1.7e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 CDJ63515.1 - 5.2e-14 51.8 0.1 6.3e-09 35.3 0.0 3.1 3 1 0 3 3 3 2 Ferrous iron transport protein B Dynamin_N PF00350.18 CDJ63515.1 - 8.8e-12 45.1 3.0 0.00058 19.7 0.1 4.4 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 CDJ63515.1 - 2.1e-11 43.6 0.9 4.3e-07 29.5 0.0 4.2 3 2 0 3 3 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CDJ63515.1 - 2.2e-10 40.0 0.1 0.00033 19.8 0.0 2.7 2 1 0 2 2 2 2 AIG1 family Miro PF08477.8 CDJ63515.1 - 7.5e-09 36.1 0.1 0.00012 22.5 0.0 3.1 3 1 0 3 3 2 2 Miro-like protein Gtr1_RagA PF04670.7 CDJ63515.1 - 1.5e-05 24.2 0.0 0.1 11.7 0.0 3.2 3 1 0 3 3 3 2 Gtr1/RagA G protein conserved region DUF258 PF03193.11 CDJ63515.1 - 3e-05 23.2 0.9 0.019 14.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Ras PF00071.17 CDJ63515.1 - 0.00023 20.6 0.0 0.099 12.0 0.0 3.4 3 1 0 3 3 3 1 Ras family ABC_tran PF00005.22 CDJ63515.1 - 0.0073 16.6 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter MobB PF03205.9 CDJ63515.1 - 0.01 15.5 0.1 4 7.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 CDJ63515.1 - 0.021 14.0 0.0 0.97 8.6 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_hydro_3_C PF01915.17 CDJ63515.1 - 0.023 14.2 0.1 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain Arf PF00025.16 CDJ63515.1 - 0.043 13.0 0.1 0.43 9.8 0.0 2.5 2 1 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 CDJ63515.1 - 0.12 11.8 0.1 26 4.2 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CDJ63515.1 - 0.14 11.7 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CDJ63515.1 - 0.15 11.7 0.1 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Pkinase PF00069.20 CDJ63516.1 - 7.2e-62 208.8 0.0 1.2e-61 208.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63516.1 - 1.9e-35 122.2 0.0 3.1e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF641 PF04859.7 CDJ63517.1 - 0.0056 16.4 2.0 0.011 15.4 1.4 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) DUF2721 PF11026.3 CDJ63517.1 - 0.016 14.8 0.9 0.033 13.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) UPF0113 PF03657.8 CDJ63518.1 - 1.8e-10 40.6 0.0 2.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) DEAD PF00270.24 CDJ63519.1 - 7.4e-26 90.6 0.0 2.3e-25 89.0 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ63519.1 - 2e-19 69.1 0.0 7.2e-19 67.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CDJ63519.1 - 0.0078 15.0 0.1 3.6 6.2 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.10 CDJ63519.1 - 0.018 14.9 0.6 0.3 10.9 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Cir_N PF10197.4 CDJ63520.1 - 2e-12 46.8 12.0 2e-12 46.8 8.3 4.4 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Ycf1 PF05758.7 CDJ63520.1 - 0.76 7.4 6.6 0.73 7.4 4.6 1.2 1 0 0 1 1 1 0 Ycf1 Slu7 PF11708.3 CDJ63520.1 - 1.1 8.9 17.0 10 5.7 8.4 2.9 2 1 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor HSP70 PF00012.15 CDJ63520.1 - 4.6 5.0 10.3 7 4.4 7.2 1.2 1 0 0 1 1 1 0 Hsp70 protein APG6 PF04111.7 CDJ63520.1 - 6.2 5.7 12.9 9 5.2 8.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 CDJ63520.1 - 6.7 6.6 20.1 12 5.7 13.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 CDJ63520.1 - 8.4 4.1 6.1 13 3.4 4.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Penicil_amidase PF01804.13 CDJ63522.1 - 8.4e-70 236.7 0.0 4.8e-63 214.3 0.0 2.2 2 0 0 2 2 2 2 Penicillin amidase BRCT PF00533.21 CDJ63523.1 - 0.015 15.4 0.0 0.67 10.1 0.0 2.6 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain EF-hand_6 PF13405.1 CDJ63524.1 - 9.9e-11 40.5 0.0 0.00054 19.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CDJ63524.1 - 1.3e-10 39.7 0.0 0.0005 19.1 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CDJ63524.1 - 3.9e-09 36.5 0.1 1.4e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CDJ63524.1 - 4.9e-05 22.8 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 CDJ63524.1 - 0.0026 17.6 0.0 1.2 9.1 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CDJ63524.1 - 0.011 15.1 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 EF hand PapD-like PF14874.1 CDJ63525.1 - 7.8e-05 22.5 0.1 0.036 14.0 0.0 4.0 4 0 0 4 4 4 1 Flagellar-associated PapD-like PapD-like PF14874.1 CDJ63527.1 - 0.0071 16.2 0.0 5.5 7.0 0.0 3.0 3 0 0 3 3 3 2 Flagellar-associated PapD-like PapD-like PF14874.1 CDJ63528.1 - 0.0001 22.1 0.0 0.004 17.0 0.0 2.2 2 0 0 2 2 2 1 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CDJ63528.1 - 0.00011 21.8 0.0 0.037 13.6 0.0 2.8 3 0 0 3 3 3 2 MSP (Major sperm protein) domain PapD_N PF00345.15 CDJ63529.1 - 0.0065 16.2 0.2 0.16 11.7 0.0 2.7 3 0 0 3 3 3 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Motile_Sperm PF00635.21 CDJ63529.1 - 0.015 14.9 0.4 0.86 9.2 0.0 3.0 3 0 0 3 3 3 0 MSP (Major sperm protein) domain Cupredoxin_1 PF13473.1 CDJ63529.1 - 0.11 12.3 0.3 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 Cupredoxin-like domain EGF_3 PF12947.2 CDJ63530.1 - 0.25 11.3 59.7 0.026 14.4 1.8 8.7 7 2 1 8 8 8 0 EGF domain Peptidase_M24 PF00557.19 CDJ63531.1 - 4.6e-35 121.0 0.0 6.5e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CDJ63531.1 - 7e-22 78.3 0.0 5.5e-17 62.5 0.0 2.7 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain zf-U1 PF06220.7 CDJ63532.1 - 0.00035 20.0 0.5 0.00035 20.0 0.4 2.0 2 0 0 2 2 2 1 U1 zinc finger WW PF00397.21 CDJ63532.1 - 0.0011 18.7 0.8 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 WW domain DUF3742 PF12553.3 CDJ63532.1 - 3.9 8.0 0.0 3.9 8.0 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) zf-RING_2 PF13639.1 CDJ63534.1 - 3.4e-06 26.7 14.3 3.4e-06 26.7 9.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CDJ63534.1 - 6e-05 22.6 10.6 6e-05 22.6 7.3 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ63534.1 - 6.6e-05 22.8 13.9 6.6e-05 22.8 9.6 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDJ63534.1 - 0.0002 20.9 14.2 0.0002 20.9 9.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ63534.1 - 0.0037 16.9 14.1 0.0037 16.9 9.8 3.1 2 2 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CDJ63534.1 - 0.0078 16.0 12.6 0.0078 16.0 8.7 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CDJ63534.1 - 0.0083 15.9 5.2 0.0083 15.9 3.6 2.1 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Sina PF03145.11 CDJ63534.1 - 0.0086 15.7 3.3 0.0086 15.7 2.3 4.4 2 1 3 5 5 5 4 Seven in absentia protein family zf-rbx1 PF12678.2 CDJ63534.1 - 0.0089 16.1 6.3 0.0089 16.1 4.4 2.6 2 1 0 2 2 1 1 RING-H2 zinc finger zf-TRAF PF02176.13 CDJ63534.1 - 0.011 16.1 5.5 0.011 16.1 3.8 4.1 2 1 2 4 4 3 0 TRAF-type zinc finger zf-RING_UBOX PF13445.1 CDJ63534.1 - 3.2 7.5 14.2 0.26 11.0 5.4 2.6 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.1 CDJ63534.1 - 7.5 6.2 18.8 0.7 9.5 6.8 3.3 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain OTU PF02338.14 CDJ63535.1 - 4.1e-15 56.4 0.0 1e-14 55.1 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CDJ63535.1 - 0.0091 15.3 0.5 0.98 8.7 0.4 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain ATP-synt_C PF00137.16 CDJ63536.1 - 2e-29 101.2 28.9 1.9e-16 59.6 4.9 3.0 2 1 0 2 2 2 2 ATP synthase subunit C 2TM PF13239.1 CDJ63536.1 - 0.45 10.6 4.1 11 6.1 0.1 2.7 2 0 0 2 2 2 0 2TM domain YwiC PF14256.1 CDJ63536.1 - 1 9.4 7.7 0.049 13.7 0.9 1.9 2 1 0 2 2 2 0 YwiC-like protein DUF3325 PF11804.3 CDJ63536.1 - 2.6 8.0 8.7 5.3 7.0 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) IMCp PF12314.3 CDJ63537.1 - 3.1e-08 33.6 21.4 3.1e-08 33.6 14.8 4.3 1 1 2 3 3 3 2 Inner membrane complex protein ParA PF10609.4 CDJ63538.1 - 1.2e-30 105.2 0.1 2.5e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like DUF59 PF01883.14 CDJ63538.1 - 4.2e-17 61.8 0.0 1.4e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF59 CbiA PF01656.18 CDJ63538.1 - 5.6e-15 55.2 0.0 9.9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CDJ63538.1 - 4.1e-09 36.5 0.0 2e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CDJ63538.1 - 6.3e-07 28.7 0.1 1.6e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 ATPase MipZ DUF971 PF06155.7 CDJ63538.1 - 2.1e-06 28.0 0.0 9.2e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF971) VirC1 PF07015.6 CDJ63538.1 - 0.00093 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein ArsA_ATPase PF02374.10 CDJ63538.1 - 0.0018 17.3 0.1 0.21 10.6 0.0 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase APS_kinase PF01583.15 CDJ63538.1 - 0.038 13.6 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 CDJ63538.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain XPC-binding PF09280.6 CDJ63539.1 - 0.0042 16.5 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 XPC-binding domain BAR_2 PF10455.4 CDJ63539.1 - 0.0072 15.2 1.0 0.0084 15.0 0.7 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Mating_C PF12737.2 CDJ63539.1 - 0.0098 14.8 0.8 0.011 14.7 0.6 1.1 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 Parvo_coat PF00740.13 CDJ63539.1 - 0.049 12.5 0.5 0.053 12.4 0.4 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 bZIP_Maf PF03131.12 CDJ63539.1 - 0.16 12.2 2.4 0.22 11.8 1.7 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Lysozyme_like PF13702.1 CDJ63540.1 - 0.045 13.2 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Lysozyme-like SR-25 PF10500.4 CDJ63541.1 - 0.0072 15.8 20.5 0.0072 15.8 14.2 2.9 2 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein CUE PF02845.11 CDJ63541.1 - 0.011 15.2 1.8 0.011 15.1 0.0 2.0 2 0 0 2 2 2 0 CUE domain UBA PF00627.26 CDJ63541.1 - 0.037 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain AAA_25 PF13481.1 CDJ63542.1 - 5.5e-05 22.6 1.1 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CDJ63542.1 - 9.1e-05 22.1 69.2 0.0012 18.4 23.5 5.6 4 1 0 4 4 4 3 AAA domain Suf PF05843.9 CDJ63542.1 - 0.00016 21.5 7.5 0.00016 21.5 5.2 6.1 5 2 0 5 5 5 1 Suppressor of forked protein (Suf) AAA_22 PF13401.1 CDJ63542.1 - 0.0013 18.9 0.0 0.0013 18.9 0.0 4.1 5 0 0 5 5 5 1 AAA domain KaiC PF06745.8 CDJ63542.1 - 0.0033 16.5 0.0 0.01 14.9 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_5 PF07728.9 CDJ63542.1 - 0.0082 15.8 0.0 0.038 13.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDJ63542.1 - 0.062 14.1 0.0 0.25 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CDJ63542.1 - 0.082 13.1 1.4 0.54 10.4 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CDJ63542.1 - 1.5 9.1 0.0 1.5 9.1 0.0 3.2 4 1 1 5 5 5 0 AAA domain Cid2 PF09774.4 CDJ63543.1 - 0.011 15.9 4.2 0.011 15.9 2.9 2.4 2 1 0 2 2 2 0 Caffeine-induced death protein 2 DUF1183 PF06682.7 CDJ63543.1 - 0.83 9.1 27.7 27 4.2 19.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2763 PF10961.3 CDJ63543.1 - 1.1 9.7 15.4 0.076 13.4 5.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2763) DUF4551 PF15087.1 CDJ63543.1 - 2.8 6.2 28.1 5 5.3 19.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.8 CDJ63543.1 - 3.1 7.6 41.7 4 7.2 28.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ63543.1 - 6.4 4.8 54.4 7.4 4.6 37.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ADIP PF11559.3 CDJ63543.1 - 6.7 6.6 43.8 3.9 7.3 1.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Hid1 PF12722.2 CDJ63543.1 - 7.2 4.1 24.3 9.1 3.8 16.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_12 PF13087.1 CDJ63544.1 - 1e-19 70.7 0.0 4.8e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain CEP44 PF15007.1 CDJ63546.1 - 8.4e-11 41.7 0.0 2e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 Centrosomal spindle body, CEP44 GPCR_chapero_1 PF11904.3 CDJ63547.1 - 2.2 7.3 10.2 3.1 6.8 7.1 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF106 PF01956.11 CDJ63547.1 - 5.2 6.5 21.7 2.9 7.3 8.6 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 Peptidase_S64 PF08192.6 CDJ63547.1 - 5.4 5.2 15.0 6.3 5.0 10.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 CDC27 PF09507.5 CDJ63547.1 - 8.8 5.4 22.6 11 5.0 15.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SR-25 PF10500.4 CDJ63548.1 - 0.087 12.2 11.3 0.24 10.8 2.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PPDFL PF15060.1 CDJ63548.1 - 4.6 7.2 9.1 1.5 8.8 0.8 2.3 2 0 0 2 2 2 0 Differentiation and proliferation regulator HdeA PF06411.6 CDJ63549.1 - 5.5 7.0 7.6 5.5 7.0 5.3 1.1 1 0 0 1 1 1 0 HdeA/HdeB family MMR1 PF08505.5 CDJ63550.1 - 0.69 9.9 28.4 0.035 14.1 12.5 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein COX16 PF14138.1 CDJ63552.1 - 0.093 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF4442 PF14539.1 CDJ63552.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) PRP38 PF03371.10 CDJ63553.1 - 2e-53 180.5 0.0 3.3e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 PRP38 family Peptidase_S15 PF02129.13 CDJ63553.1 - 0.55 9.6 15.7 0.66 9.3 3.0 2.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) E_Pc_C PF06752.7 CDJ63554.1 - 0.007 15.8 12.9 0.007 15.8 9.0 8.1 5 2 1 7 7 7 1 Enhancer of Polycomb C-terminus UbiD PF01977.11 CDJ63554.1 - 0.3 9.4 1.9 0.63 8.4 0.8 1.9 1 1 1 2 2 2 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase P30 PF07390.6 CDJ63554.1 - 4.7 6.6 8.0 0.1 12.1 0.5 1.8 2 0 0 2 2 2 0 Mycoplasma P30 protein SPX PF03105.14 CDJ63555.1 - 0.017 14.9 11.2 0.024 14.4 7.8 1.3 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.4 CDJ63555.1 - 0.1 10.8 48.6 0.14 10.3 33.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dala_Dala_lig_N PF01820.16 CDJ63555.1 - 2.7 8.3 13.7 1.6 9.0 1.3 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Pap_E4 PF02711.9 CDJ63555.1 - 5.5 7.8 21.2 5 8.0 5.9 2.4 2 0 0 2 2 2 0 E4 protein Prp19 PF08606.6 CDJ63556.1 - 2.2e-17 62.5 6.3 2.2e-17 62.5 4.4 2.4 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 CDJ63556.1 - 1.2e-12 47.1 0.0 8.2e-09 35.0 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat CENP-H PF05837.7 CDJ63556.1 - 0.0026 17.9 2.2 0.0057 16.8 0.8 2.0 2 0 0 2 2 2 1 Centromere protein H (CENP-H) TBCA PF02970.11 CDJ63556.1 - 0.0083 16.1 3.0 0.014 15.4 2.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor A GED PF02212.13 CDJ63556.1 - 0.81 9.6 3.8 1.5 8.7 2.7 1.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain Sporozoite_P67 PF05642.6 CDJ63556.1 - 2.8 5.7 15.8 4.7 4.9 11.0 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DivIC PF04977.10 CDJ63557.1 - 0.00037 19.9 2.7 0.00037 19.9 1.9 14.4 13 2 3 16 16 16 4 Septum formation initiator RILP PF11461.3 CDJ63557.1 - 0.033 14.3 19.0 0.21 11.7 0.2 5.5 5 0 0 5 5 5 0 Rab interacting lysosomal protein Pox_L3_FP4 PF03339.9 CDJ63557.1 - 0.035 12.5 0.3 0.063 11.7 0.2 1.3 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein TPT PF03151.11 CDJ63558.1 - 0.022 14.3 11.4 0.055 13.1 2.1 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family Metallophos PF00149.23 CDJ63559.1 - 0.012 14.9 0.7 0.94 8.8 0.1 2.4 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase Glyco_hydro_67N PF03648.9 CDJ63560.1 - 0.0031 17.5 0.7 0.0085 16.1 0.5 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus WD40 PF00400.27 CDJ63560.1 - 0.058 13.2 10.0 0.24 11.3 0.1 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat PUB PF09409.5 CDJ63561.1 - 2.7e-14 52.6 0.0 6e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 PUB domain UBA PF00627.26 CDJ63561.1 - 0.00027 20.6 0.0 0.00065 19.4 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain V_ATPase_I PF01496.14 CDJ63561.1 - 0.44 8.3 5.9 0.53 8.0 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 CDJ63561.1 - 4 5.5 11.3 4.9 5.2 7.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein HSP70 PF00012.15 CDJ63561.1 - 8.9 4.0 10.7 15 3.3 7.4 1.3 1 0 0 1 1 1 0 Hsp70 protein ArfGap PF01412.13 CDJ63562.1 - 2.7e-28 98.1 0.0 6.1e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TFIIA PF03153.8 CDJ63562.1 - 8.5 6.1 9.5 13 5.5 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M18 PF02127.10 CDJ63563.1 - 1.3e-129 432.4 0.0 2e-129 431.9 0.0 1.2 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CDJ63563.1 - 0.00036 19.3 0.0 0.0031 16.3 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Sec23_trunk PF04811.10 CDJ63564.1 - 3.1e-20 72.5 0.0 5.8e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CDJ63564.1 - 2.4e-19 68.6 1.1 4.9e-19 67.6 0.3 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CDJ63564.1 - 5.2e-11 41.9 4.9 1.2e-10 40.7 3.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CDJ63564.1 - 1.7e-08 34.8 0.0 1e-07 32.3 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain WD40 PF00400.27 CDJ63565.1 - 5.8e-16 57.6 8.1 1.8e-05 24.3 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat OmpH PF03938.9 CDJ63565.1 - 0.036 14.0 3.8 0.061 13.2 2.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FliD_N PF02465.13 CDJ63565.1 - 0.041 14.2 0.4 0.087 13.1 0.3 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF3840 PF12944.2 CDJ63565.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) Metal_resist PF13801.1 CDJ63565.1 - 0.054 13.4 8.5 0.16 12.0 5.9 1.7 1 0 0 1 1 1 0 Heavy-metal resistance Sugarporin_N PF11471.3 CDJ63565.1 - 0.16 11.6 7.7 0.29 10.8 5.3 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension HBS1_N PF08938.5 CDJ63565.1 - 0.24 11.5 1.9 0.64 10.1 1.3 1.7 1 0 0 1 1 1 0 HBS1 N-terminus RBD-FIP PF09457.5 CDJ63565.1 - 6.7 6.5 9.4 11 5.8 6.5 1.3 1 0 0 1 1 1 0 FIP domain HECT PF00632.20 CDJ63566.1 - 4.1e-33 114.8 0.0 1.5e-29 103.1 0.0 2.3 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) AKAP7_NLS PF10469.4 CDJ63567.1 - 3.7e-38 131.3 0.1 5e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 CDJ63567.1 - 0.00059 19.5 0.4 0.0012 18.6 0.2 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DUF1465 PF07323.7 CDJ63567.1 - 0.012 15.2 0.2 0.027 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Inositol_P PF00459.20 CDJ63568.1 - 1.7e-17 63.5 0.0 1.3e-05 24.6 0.0 4.3 4 0 0 4 4 4 4 Inositol monophosphatase family Cons_hypoth95 PF03602.10 CDJ63569.1 - 7.3e-37 126.5 0.0 1.4e-35 122.3 0.0 2.3 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 CDJ63569.1 - 7.2e-12 45.3 0.8 4.3e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ63569.1 - 3.4e-08 34.0 0.0 8.2e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ63569.1 - 3.2e-06 26.7 0.0 4.7e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CDJ63569.1 - 0.003 16.7 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CDJ63569.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain WGR PF05406.10 CDJ63569.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 WGR domain UPF0020 PF01170.13 CDJ63569.1 - 0.049 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ABM PF03992.11 CDJ63570.1 - 0.0041 17.1 0.1 0.023 14.7 0.0 2.3 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase FTR PF01913.13 CDJ63570.1 - 0.16 11.6 1.4 0.27 10.9 0.1 2.0 1 1 1 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Peptidase_S15 PF02129.13 CDJ63570.1 - 0.7 9.2 4.1 1.1 8.5 2.8 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TnpV PF14198.1 CDJ63570.1 - 0.76 9.6 7.6 1.2 9.0 5.2 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV AIRS_C PF02769.17 CDJ63572.1 - 5.6e-15 55.6 1.4 1.2e-13 51.3 1.0 2.5 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain Pyr_redox PF00070.22 CDJ63572.1 - 1.4e-09 38.2 0.3 0.00052 20.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AIRS PF00586.19 CDJ63572.1 - 8.3e-08 32.3 0.0 2.9e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Lycopene_cycl PF05834.7 CDJ63572.1 - 0.0083 15.0 0.1 0.016 14.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CDJ63572.1 - 0.062 13.1 0.0 1.8 8.4 0.0 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-DHHC PF01529.15 CDJ63573.1 - 9.1e-11 41.4 11.2 9.1e-11 41.4 7.8 2.9 3 0 0 3 3 3 2 DHHC palmitoyltransferase RabGAP-TBC PF00566.13 CDJ63574.1 - 2.2e-41 141.6 0.0 4.7e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box PF00646.28 CDJ63574.1 - 0.00087 18.8 1.0 0.0019 17.8 0.7 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDJ63574.1 - 0.031 13.9 1.4 0.073 12.8 1.0 1.6 1 0 0 1 1 1 0 F-box-like DUF4591 PF15261.1 CDJ63574.1 - 0.17 12.1 6.8 0.32 11.2 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Gastrin PF00918.12 CDJ63574.1 - 1.8 9.3 7.3 3.7 8.3 5.0 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family GHMP_kinases_N PF00288.21 CDJ63575.1 - 0.053 13.5 1.2 0.33 11.0 0.1 2.6 2 0 0 2 2 2 0 GHMP kinases N terminal domain DUF2058 PF09831.4 CDJ63575.1 - 0.71 9.7 9.9 1.4 8.8 6.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Rhodanese PF00581.15 CDJ63576.1 - 3e-17 62.9 0.0 2.2e-05 24.7 0.0 4.3 3 1 0 3 3 3 3 Rhodanese-like domain Spc24 PF08286.6 CDJ63576.1 - 0.0036 16.9 2.0 0.0036 16.9 1.4 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 AAA_23 PF13476.1 CDJ63576.1 - 0.056 13.7 0.5 7.1 6.8 0.6 2.2 2 0 0 2 2 2 0 AAA domain SPT16 PF08644.6 CDJ63576.1 - 0.92 9.3 5.6 0.16 11.8 0.5 1.9 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) SNase PF00565.12 CDJ63577.1 - 1.6e-08 34.7 0.0 3.5e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Staphylococcal nuclease homologue RRM_1 PF00076.17 CDJ63578.1 - 0.0024 17.4 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63578.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.22 CDJ63579.1 - 2.5e-17 62.9 0.0 4.7e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDJ63579.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 RNase H RVT_3 PF13456.1 CDJ63579.1 - 0.046 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like gag-asp_proteas PF13975.1 CDJ63580.1 - 3.1e-09 36.5 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ63580.1 - 2.4e-08 34.3 0.0 4.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CDJ63580.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CDJ63580.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.7 CDJ63580.1 - 0.041 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Retrotrans_gag PF03732.12 CDJ63581.1 - 0.0023 17.9 0.0 0.012 15.6 0.0 2.2 3 0 0 3 3 3 1 Retrotransposon gag protein DUF1470 PF07336.6 CDJ63581.1 - 0.1 12.9 6.2 0.35 11.2 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) DUF3038 PF11237.3 CDJ63582.1 - 0.061 13.1 0.2 0.095 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) IncA PF04156.9 CDJ63583.1 - 1.6 8.3 18.0 0.35 10.4 0.1 3.3 3 0 0 3 3 3 0 IncA protein Metallothio_11 PF02066.10 CDJ63584.1 - 0.11 12.3 0.5 0.11 12.3 0.3 2.6 2 0 0 2 2 2 0 Metallothionein family 11 CDK2AP PF09806.4 CDJ63585.1 - 0.089 13.0 1.8 0.12 12.6 0.5 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CDJ63585.1 - 1.3 8.4 8.2 0.1 12.0 1.9 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1633 PF07794.6 CDJ63585.1 - 3.1 5.6 7.7 4.9 4.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) DUF4217 PF13959.1 CDJ63586.1 - 1.8e-14 52.9 0.1 6.3e-14 51.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CDJ63586.1 - 0.0011 18.8 0.0 0.0039 17.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hid1 PF12722.2 CDJ63586.1 - 0.63 7.6 4.6 0.88 7.1 3.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Shadoo PF14999.1 CDJ63586.1 - 1.3 8.9 16.2 2.1 8.1 0.1 2.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Rtf2 PF04641.7 CDJ63586.1 - 1.3 8.1 16.8 1 8.4 6.9 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger YscJ_FliF_C PF08345.6 CDJ63586.1 - 7 6.6 12.9 0.15 12.0 4.1 1.7 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal SR-25 PF10500.4 CDJ63587.1 - 0.0058 16.1 5.6 0.0058 16.1 3.9 2.8 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.3 CDJ63587.1 - 0.097 12.0 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 Spt20 family PAT1 PF09770.4 CDJ63587.1 - 3.1 5.9 15.7 4.2 5.4 10.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1777 PF08648.7 CDJ63588.1 - 2.7 7.6 22.9 3.3 7.4 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) SR-25 PF10500.4 CDJ63589.1 - 0.00046 19.7 6.8 0.00056 19.4 4.7 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.2 CDJ63589.1 - 0.55 9.8 8.0 0.67 9.5 5.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM60A PF15396.1 CDJ63589.1 - 0.58 9.8 8.2 0.64 9.7 5.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF1675 PF07897.6 CDJ63589.1 - 0.76 9.5 9.6 0.86 9.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Pex16 PF08610.5 CDJ63589.1 - 1 8.2 6.4 1.3 7.9 4.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Parvo_coat PF00740.13 CDJ63589.1 - 1.1 8.0 10.5 1.2 7.9 7.3 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PAT1 PF09770.4 CDJ63589.1 - 1.8 6.7 24.3 2 6.5 16.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_DNAp_acc PF04929.7 CDJ63589.1 - 1.9 7.3 10.0 2.1 7.2 6.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDHD PF02862.12 CDJ63589.1 - 2.7 7.7 7.7 3.7 7.2 5.3 1.2 1 0 0 1 1 1 0 DDHD domain CDC27 PF09507.5 CDJ63589.1 - 2.7 7.1 14.5 3.1 6.9 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Suf PF05843.9 CDJ63589.1 - 2.9 7.5 13.8 3.8 7.1 9.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.12 CDJ63589.1 - 3.7 6.2 7.8 4.6 5.9 5.4 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.6 CDJ63589.1 - 3.7 5.7 8.5 4.1 5.6 5.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3807 PF12720.2 CDJ63589.1 - 3.9 7.6 13.3 5.5 7.1 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF874 PF05917.6 CDJ63589.1 - 4.3 6.0 13.6 5.4 5.7 9.4 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) FLO_LFY PF01698.11 CDJ63589.1 - 5 5.8 10.8 6.7 5.4 7.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_UL87 PF03043.9 CDJ63589.1 - 6.1 5.1 7.3 7.1 4.8 5.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4647 PF15504.1 CDJ63589.1 - 6.8 5.4 14.8 8.2 5.1 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Rtf2 PF04641.7 CDJ63589.1 - 7 5.7 13.6 9.1 5.3 9.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RskA PF10099.4 CDJ63589.1 - 7.2 6.3 33.4 2.4 7.8 10.5 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Med15 PF09606.5 CDJ63589.1 - 7.5 4.6 36.3 9.5 4.2 25.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2201_N PF13203.1 CDJ63589.1 - 7.7 5.5 18.4 9.4 5.3 12.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain AP2 PF00847.15 CDJ63590.1 - 1.9e-05 24.7 0.2 2.3e-05 24.4 0.2 1.1 1 0 0 1 1 1 1 AP2 domain DUF2188 PF09954.4 CDJ63590.1 - 0.17 11.8 1.0 0.54 10.2 0.7 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF4228 PF14009.1 CDJ63591.1 - 0.66 10.0 19.0 1.6 8.8 7.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Ribosomal_60s PF00428.14 CDJ63591.1 - 1.7 9.1 27.2 0.18 12.2 2.0 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein U1snRNP70_N PF12220.3 CDJ63594.1 - 2.8 8.3 7.7 0.4 11.0 1.6 2.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SMC_N PF02463.14 CDJ63596.1 - 3.4 6.8 17.1 7.2 5.7 11.9 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Tetraspannin PF00335.15 CDJ63598.1 - 0.0003 20.1 0.9 0.0015 17.8 0.7 2.1 1 1 0 1 1 1 1 Tetraspanin family RCR PF12273.3 CDJ63598.1 - 0.0012 19.3 3.8 0.0012 19.3 2.7 2.6 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Neur_chan_memb PF02932.11 CDJ63598.1 - 0.0036 17.2 15.9 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region FHIPEP PF00771.15 CDJ63598.1 - 0.17 10.2 10.7 0.13 10.5 0.2 2.0 2 0 0 2 2 2 0 FHIPEP family Adaptin_binding PF10199.4 CDJ63598.1 - 1.9 8.7 20.9 1.4 9.1 0.3 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 PAT1 PF09770.4 CDJ63598.1 - 1.9 6.6 41.3 0.46 8.6 9.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CD20 PF04103.10 CDJ63598.1 - 2.3 8.1 5.3 1.9 8.4 0.0 2.4 1 1 1 2 2 2 0 CD20-like family CCDC84 PF14968.1 CDJ63598.1 - 2.3 7.6 25.2 2 7.8 7.6 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 DUF3729 PF12526.3 CDJ63598.1 - 4.1 8.7 11.8 6.9 8.0 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) CRISPR_Cse2 PF09485.5 CDJ63599.1 - 2.2 8.3 6.6 7.6 6.5 0.1 2.4 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) NAD_binding_4 PF07993.7 CDJ63600.1 - 3.8e-12 45.6 0.0 9.7e-09 34.5 0.0 2.6 2 0 0 2 2 2 2 Male sterility protein Sterile PF03015.14 CDJ63600.1 - 1.3e-11 44.5 0.0 3.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.16 CDJ63600.1 - 5.7e-09 35.5 0.0 1.6e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase Surface_antigen PF11054.3 CDJ63603.1 - 0.083 12.2 2.2 2.8 7.2 1.5 2.1 1 1 0 1 1 1 0 Sporozoite TA4 surface antigen CAP PF00188.21 CDJ63603.1 - 0.13 12.7 1.0 0.26 11.7 0.7 1.7 1 1 0 1 1 1 0 Cysteine-rich secretory protein family CAP PF00188.21 CDJ63604.1 - 0.07 13.6 0.3 0.13 12.7 0.2 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Phytase PF02333.10 CDJ63605.1 - 0.027 13.1 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Phytase rve PF00665.21 CDJ63606.1 - 5e-08 33.0 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CDJ63606.1 - 5.1e-08 32.4 9.0 0.0014 18.4 1.3 2.5 2 0 0 2 2 2 2 Zinc knuckle gag-asp_proteas PF13975.1 CDJ63606.1 - 6.3e-08 32.3 0.1 1.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ63606.1 - 9.2e-06 26.0 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.1 CDJ63606.1 - 0.0058 16.1 2.1 1.7 8.2 0.1 2.7 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ63606.1 - 0.023 14.7 1.8 0.045 13.7 1.3 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.1 CDJ63606.1 - 2.6 7.8 4.8 4.9 6.9 0.4 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ63606.1 - 3.6 7.3 4.8 10 5.8 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Med15 PF09606.5 CDJ63608.1 - 0.0091 14.2 44.1 0.013 13.6 30.6 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal V_ATPase_I PF01496.14 CDJ63608.1 - 0.036 11.9 15.2 0.049 11.4 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lipase_GDSL PF00657.17 CDJ63608.1 - 0.14 11.9 3.6 0.22 11.3 2.5 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Tweety PF04906.8 CDJ63608.1 - 0.32 9.3 21.4 0.023 13.0 1.1 2.8 2 1 0 2 2 2 0 Tweety Spc7 PF08317.6 CDJ63608.1 - 0.38 9.3 18.8 0.52 8.9 13.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ALMT PF11744.3 CDJ63608.1 - 0.58 8.7 3.9 0.72 8.4 2.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF342 PF03961.8 CDJ63608.1 - 0.9 7.8 10.2 1.4 7.2 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spore_YhcN_YlaJ PF09580.5 CDJ63608.1 - 0.91 9.6 12.5 2.4 8.2 8.7 1.7 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Macoilin PF09726.4 CDJ63608.1 - 1.3 7.1 22.2 2 6.5 15.4 1.2 1 0 0 1 1 1 0 Transmembrane protein MAD PF05557.8 CDJ63608.1 - 2.1 6.3 30.0 2.8 5.9 20.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Init_tRNA_PT PF04179.7 CDJ63608.1 - 2.9 6.6 9.7 3.9 6.2 6.7 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase PAT1 PF09770.4 CDJ63608.1 - 3.4 5.8 33.9 4.2 5.4 23.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLRV_ORF5 PF01690.12 CDJ63608.1 - 7.1 5.6 13.8 9.9 5.1 9.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF3584 PF12128.3 CDJ63608.1 - 9 3.4 36.8 14 2.8 25.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) rve PF00665.21 CDJ63610.1 - 1.5e-17 63.8 0.0 1.9e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ63610.1 - 0.0025 17.3 0.1 0.0042 16.5 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain GLTSCR1 PF15249.1 CDJ63610.1 - 0.082 13.0 0.1 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Glioma tumor suppressor candidate region MMR_HSR1 PF01926.18 CDJ63611.1 - 3.8e-16 59.0 0.0 1e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CDJ63611.1 - 1.2e-05 24.5 0.0 2.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CDJ63611.1 - 5e-05 22.6 0.0 9.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CDJ63611.1 - 0.00034 20.4 1.7 0.0046 16.7 0.1 2.4 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 CDJ63611.1 - 0.01 16.3 0.2 0.038 14.4 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein CDK2AP PF09806.4 CDJ63611.1 - 0.019 15.1 4.7 0.019 15.1 3.3 3.4 3 1 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein Med15 PF09606.5 CDJ63611.1 - 0.12 10.5 19.1 0.012 13.8 4.4 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal AIG1 PF04548.11 CDJ63611.1 - 1.4 8.0 7.1 0.63 9.1 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Activator_LAG-3 PF11498.3 CDJ63611.1 - 2.2 6.9 17.1 4.5 5.9 11.8 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ctr PF04145.10 CDJ63611.1 - 9.9 6.2 8.5 12 5.9 0.4 2.6 3 0 0 3 3 3 0 Ctr copper transporter family Tropomyosin_1 PF12718.2 CDJ63612.1 - 0.00068 19.5 10.0 0.00068 19.5 6.9 2.0 2 0 0 2 2 2 1 Tropomyosin like Phlebovirus_NSM PF07246.6 CDJ63612.1 - 0.015 14.4 2.1 0.023 13.8 1.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3391 PF11871.3 CDJ63612.1 - 0.023 14.8 3.0 0.43 10.7 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) PAH PF02671.16 CDJ63612.1 - 0.047 13.3 2.1 0.048 13.2 0.3 1.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat Talin_middle PF09141.5 CDJ63612.1 - 0.074 12.7 3.5 0.12 12.0 0.7 2.1 2 0 0 2 2 2 0 Talin, middle domain Mnd1 PF03962.10 CDJ63612.1 - 0.079 12.6 13.6 0.022 14.4 7.0 1.7 2 0 0 2 2 2 0 Mnd1 family PspA_IM30 PF04012.7 CDJ63612.1 - 0.15 11.3 13.5 0.071 12.4 6.1 2.1 2 0 0 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.3 CDJ63612.1 - 0.15 11.8 15.4 0.42 10.4 8.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CDJ63612.1 - 0.34 10.4 13.2 0.063 12.8 5.8 1.8 2 0 0 2 2 2 0 IncA protein GAS PF13851.1 CDJ63612.1 - 0.63 9.1 12.7 0.23 10.6 6.1 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 CDJ63612.1 - 0.73 9.6 15.6 0.21 11.4 5.1 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.6 CDJ63612.1 - 0.78 9.1 14.1 0.5 9.8 7.7 2.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 TBPIP PF07106.8 CDJ63612.1 - 1.1 8.7 10.2 0.99 8.9 5.6 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 CDJ63612.1 - 1.2 8.8 11.9 1.6 8.4 6.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Occludin_ELL PF07303.8 CDJ63612.1 - 1.3 9.7 7.3 0.66 10.7 2.8 1.9 2 0 0 2 2 2 0 Occludin homology domain DUF342 PF03961.8 CDJ63612.1 - 1.5 7.1 6.2 0.4 9.0 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 CDJ63612.1 - 2 7.4 13.7 0.46 9.4 6.9 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 CDJ63612.1 - 2.6 8.4 9.8 2 8.8 5.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 CDJ63612.1 - 3.2 7.7 15.1 1.4 8.9 7.9 2.1 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 CDJ63612.1 - 4.2 7.2 18.4 1.4 8.7 10.0 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 CDJ63612.1 - 4.3 7.3 13.0 11 6.0 1.3 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NYD-SP28_assoc PF14775.1 CDJ63612.1 - 4.5 7.0 7.4 7.9 6.2 3.0 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF16 PF01519.11 CDJ63612.1 - 6.8 6.9 8.2 9.5 6.5 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.14 CDJ63612.1 - 8.5 4.0 7.8 8.8 4.0 5.3 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_60s PF00428.14 CDJ63613.1 - 0.3 11.5 83.1 0.16 12.3 5.7 5.5 4 1 1 5 5 5 0 60s Acidic ribosomal protein TMPIT PF07851.8 CDJ63613.1 - 0.95 8.4 6.4 1.7 7.6 4.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein FimP PF09766.4 CDJ63614.1 - 0.003 16.6 28.7 0.067 12.2 13.2 2.3 2 0 0 2 2 2 2 Fms-interacting protein zf-DHHC PF01529.15 CDJ63614.1 - 5 6.4 12.3 0.74 9.1 2.8 2.7 3 0 0 3 3 3 0 DHHC palmitoyltransferase PBP1_TM PF14812.1 CDJ63614.1 - 7 7.0 8.2 19 5.6 3.8 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FLO_LFY PF01698.11 CDJ63614.1 - 9 5.0 23.8 0.56 9.0 9.0 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Sec62 PF03839.11 CDJ63614.1 - 9.9 5.4 7.5 19 4.5 4.0 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 Acetyltransf_1 PF00583.19 CDJ63615.1 - 2.8e-05 24.0 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDJ63615.1 - 0.00049 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Apt1 PF10351.4 CDJ63615.1 - 0.0032 16.3 3.4 0.0032 16.3 2.3 3.6 3 1 0 3 3 3 1 Golgi-body localisation protein domain Corona_nucleoca PF00937.13 CDJ63615.1 - 0.007 15.3 29.6 0.007 15.3 20.5 4.5 3 1 2 5 5 5 1 Coronavirus nucleocapsid protein DUF2910 PF11139.3 CDJ63615.1 - 0.091 11.8 12.0 0.072 12.2 6.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) Zip PF02535.17 CDJ63615.1 - 1.4 7.8 21.5 0.41 9.6 0.3 3.2 3 0 0 3 3 3 0 ZIP Zinc transporter Dynamin_N PF00350.18 CDJ63615.1 - 1.6 8.5 19.0 0.89 9.3 2.1 2.7 2 0 0 2 2 2 0 Dynamin family F-actin_cap_A PF01267.12 CDJ63616.1 - 2.2e-14 53.1 1.2 1.3e-11 44.0 0.4 3.1 1 1 1 2 2 2 2 F-actin capping protein alpha subunit Semialdhyde_dhC PF02774.13 CDJ63616.1 - 0.023 14.5 1.6 0.023 14.5 1.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain DUF45 PF01863.12 CDJ63616.1 - 0.26 11.0 13.3 0.12 12.1 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 Med15 PF09606.5 CDJ63616.1 - 0.29 9.2 40.2 0.68 8.0 16.3 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4604 PF15377.1 CDJ63616.1 - 1.1 9.4 29.1 2.5 8.2 8.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) PAT1 PF09770.4 CDJ63616.1 - 4.1 5.5 35.1 3.3 5.8 11.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Phostensin_N PF13916.1 CDJ63616.1 - 9.3 6.3 15.4 8.8 6.3 1.2 2.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Adaptin_N PF01602.15 CDJ63618.1 - 1.6e-73 247.8 0.0 1.1e-56 192.2 0.4 2.4 1 1 1 2 2 2 2 Adaptin N terminal region Ribul_P_3_epim PF00834.14 CDJ63618.1 - 9.4e-31 106.4 0.0 1.9e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family HEAT_2 PF13646.1 CDJ63618.1 - 5.8e-08 32.9 1.2 0.00037 20.7 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 CDJ63618.1 - 3.5e-06 26.9 0.4 0.00032 20.6 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Sporozoite_P67 PF05642.6 CDJ63618.1 - 6.2e-05 21.0 3.5 6.2e-05 21.0 2.5 2.1 2 0 0 2 2 2 1 Sporozoite P67 surface antigen HEAT PF02985.17 CDJ63618.1 - 0.00022 21.0 0.2 0.021 14.9 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat CDK2AP PF09806.4 CDJ63618.1 - 0.00035 20.8 21.6 0.0006 20.0 3.2 3.5 3 0 0 3 3 3 2 Cyclin-dependent kinase 2-associated protein ApbA_C PF08546.6 CDJ63623.1 - 0.28 11.1 0.0 0.28 11.1 0.0 2.2 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DAP_epimerase PF01678.14 CDJ63624.1 - 0.27 11.1 1.7 0.38 10.6 1.2 1.2 1 0 0 1 1 1 0 Diaminopimelate epimerase DUF4228 PF14009.1 CDJ63624.1 - 0.93 9.6 18.4 1.3 9.1 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Senescence_reg PF04520.8 CDJ63624.1 - 1.1 9.8 16.1 1.4 9.4 11.2 1.4 1 0 0 1 1 1 0 Senescence regulator DUF737 PF05300.6 CDJ63624.1 - 1.5 8.7 12.3 1.8 8.5 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Corona_nucleoca PF00937.13 CDJ63624.1 - 4.4 6.1 24.5 5.9 5.7 17.0 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Herpes_DNAp_acc PF04929.7 CDJ63624.1 - 5 5.9 12.6 6.1 5.7 8.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rep_fac-A_3 PF08661.6 CDJ63625.1 - 4.4e-05 23.3 0.0 5.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Med15 PF09606.5 CDJ63626.1 - 0.28 9.3 31.9 0.37 8.9 22.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC27 PF09507.5 CDJ63626.1 - 0.3 10.2 4.3 0.41 9.8 3.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 His_Phos_1 PF00300.17 CDJ63627.1 - 6.7e-09 36.0 0.1 8.4e-08 32.4 0.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NDUF_B5 PF09781.4 CDJ63627.1 - 0.1 11.8 0.1 0.24 10.6 0.1 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Med15 PF09606.5 CDJ63627.1 - 7.7 4.5 33.0 0.76 7.9 1.1 2.5 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3446 PF11928.3 CDJ63627.1 - 7.9 6.7 27.8 6.5 7.0 2.3 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3446) His_Phos_1 PF00300.17 CDJ63628.1 - 1.5e-18 67.3 0.0 4.2e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 CDJ63629.1 - 1.2e-05 25.5 0.1 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 CDJ63630.1 - 7.1e-05 22.9 0.1 0.011 15.8 0.1 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SPC22 PF04573.7 CDJ63631.1 - 8.4e-37 126.0 0.0 1e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit TSA PF03249.8 CDJ63631.1 - 0.0039 15.7 0.7 0.0048 15.4 0.5 1.1 1 0 0 1 1 1 1 Type specific antigen LSM PF01423.17 CDJ63632.1 - 4.6e-16 58.1 0.3 5.7e-16 57.8 0.2 1.2 1 1 0 1 1 1 1 LSM domain zf-C3HC4 PF00097.20 CDJ63633.1 - 0.038 13.6 0.7 0.085 12.5 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2196 PF09962.4 CDJ63634.1 - 3.3e-05 23.5 28.0 15 5.4 0.0 11.8 9 5 4 13 13 13 3 Uncharacterized conserved protein (DUF2196) CFTR_R PF14396.1 CDJ63634.1 - 0.7 9.2 10.7 5.2 6.3 0.0 5.7 8 0 0 8 8 8 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Peptidase_S64 PF08192.6 CDJ63636.1 - 2 6.6 6.2 2.5 6.3 4.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_viral_N PF00242.12 CDJ63636.1 - 9.3 5.1 10.7 15 4.5 7.4 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain UCH PF00443.24 CDJ63637.1 - 2.8e-33 115.1 0.0 3.7e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CDJ63637.1 - 1.3e-06 27.6 0.0 4e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family UCH_1 PF13423.1 CDJ63637.1 - 4.5e-06 26.3 0.0 0.0082 15.6 0.0 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.1 CDJ63637.1 - 0.076 13.2 0.0 0.74 10.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain Thg1C PF14413.1 CDJ63638.1 - 0.065 12.9 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Thg1 C terminal domain CTK3 PF12243.3 CDJ63638.1 - 0.076 12.6 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF761 PF05553.6 CDJ63638.1 - 0.17 11.2 0.6 0.45 9.9 0.4 1.6 1 0 0 1 1 1 0 Cotton fibre expressed protein GTP_cyclohydroI PF01227.17 CDJ63639.1 - 0.2 10.9 0.8 0.43 9.8 0.5 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase I DUF2398 PF09661.5 CDJ63640.1 - 0.024 13.3 0.2 0.024 13.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2398) KH_1 PF00013.24 CDJ63641.1 - 3.7e-07 29.6 0.2 2e-06 27.3 0.2 1.9 2 0 0 2 2 2 1 KH domain Mem_trans PF03547.13 CDJ63642.1 - 0.03 12.6 6.4 0.082 11.1 2.0 2.2 2 0 0 2 2 2 0 Membrane transport protein Mnd1 PF03962.10 CDJ63642.1 - 0.38 10.3 5.2 1.2 8.7 0.2 2.2 2 0 0 2 2 2 0 Mnd1 family DNA_pol_viral_N PF00242.12 CDJ63642.1 - 5.7 5.8 20.3 10 4.9 14.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Corona_nucleoca PF00937.13 CDJ63645.1 - 0.0023 16.9 6.7 0.0037 16.2 4.7 1.3 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein DUF4647 PF15504.1 CDJ63645.1 - 0.0037 16.1 3.1 0.0053 15.6 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) Spt20 PF12090.3 CDJ63645.1 - 0.009 15.3 1.8 0.01 15.1 1.3 1.2 1 0 0 1 1 1 1 Spt20 family Apt1 PF10351.4 CDJ63645.1 - 0.014 14.3 2.0 0.018 13.9 1.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spore_YhcN_YlaJ PF09580.5 CDJ63645.1 - 0.048 13.7 1.6 0.062 13.4 1.1 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) OCIA PF07051.6 CDJ63645.1 - 0.067 12.6 0.6 0.1 11.9 0.4 1.2 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF2828 PF11443.3 CDJ63645.1 - 0.075 11.2 2.6 0.09 10.9 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) OSTbeta PF15048.1 CDJ63645.1 - 0.1 12.7 1.5 0.14 12.2 1.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Med15 PF09606.5 CDJ63645.1 - 0.11 10.6 14.4 0.17 10.0 10.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-DHHC PF01529.15 CDJ63645.1 - 0.13 11.6 0.2 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase RED_N PF07808.8 CDJ63645.1 - 0.17 11.0 8.0 0.24 10.5 5.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Serinc PF03348.10 CDJ63645.1 - 0.17 10.5 0.7 0.18 10.4 0.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 CDJ63645.1 - 0.2 9.3 15.0 0.26 8.9 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) OATP PF03137.15 CDJ63645.1 - 0.24 9.4 0.6 0.31 9.0 0.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF775 PF05603.7 CDJ63645.1 - 0.25 10.8 4.5 0.44 10.0 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) RAB3GAP2_N PF14655.1 CDJ63645.1 - 0.35 9.8 4.6 0.48 9.3 3.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus EIIBC-GUT_N PF03612.9 CDJ63645.1 - 0.41 10.2 2.3 0.6 9.6 1.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Conotoxin PF02950.12 CDJ63645.1 - 0.53 11.1 4.4 1 10.1 3.0 1.4 1 0 0 1 1 1 0 Conotoxin DUF605 PF04652.11 CDJ63645.1 - 0.65 9.3 11.5 0.89 8.8 8.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF4557 PF15101.1 CDJ63645.1 - 0.65 9.7 7.4 0.95 9.2 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF788 PF05620.6 CDJ63645.1 - 0.69 9.7 6.4 1.1 9.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) EST1_DNA_bind PF10373.4 CDJ63645.1 - 0.89 8.7 6.1 1.1 8.3 3.6 1.6 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain DivIC PF04977.10 CDJ63645.1 - 1 8.9 10.8 2.3 7.7 7.5 1.6 1 0 0 1 1 1 0 Septum formation initiator ERF PF04404.7 CDJ63645.1 - 2.9 7.3 10.8 4.5 6.7 7.5 1.2 1 0 0 1 1 1 0 ERF superfamily Activator_LAG-3 PF11498.3 CDJ63645.1 - 6.1 5.4 20.3 8.7 4.9 14.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PHD_3 PF13922.1 CDJ63645.1 - 8.8 6.6 11.1 16 5.7 7.7 1.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx AAA_23 PF13476.1 CDJ63645.1 - 9.7 6.4 11.0 13 6.0 7.7 1.1 1 0 0 1 1 1 0 AAA domain ETRAMP PF09716.5 CDJ63645.1 - 9.7 6.2 5.8 2.1 8.3 0.1 2.1 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_UL87 PF03043.9 CDJ63646.1 - 6.1e-07 28.2 0.0 0.12 10.7 0.0 2.3 1 1 1 2 2 2 1 Herpesvirus UL87 family CheD PF03975.8 CDJ63646.1 - 0.034 13.8 0.1 0.077 12.7 0.1 1.5 1 0 0 1 1 1 0 CheD chemotactic sensory transduction Ribosomal_60s PF00428.14 CDJ63646.1 - 7.8 6.9 18.4 16 5.9 6.5 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-CCCH PF00642.19 CDJ63647.1 - 1.2e-05 24.8 18.9 0.0034 17.0 0.5 3.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDJ63647.1 - 0.002 18.0 17.3 0.11 12.5 0.3 3.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type oligo_HPY PF08352.7 CDJ63647.1 - 3.5 8.0 6.7 2.2 8.6 1.3 3.1 2 1 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Med15 PF09606.5 CDJ63648.1 - 0.15 10.1 23.6 0.19 9.8 16.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAP PF07174.6 CDJ63648.1 - 1.5 8.0 21.6 2.4 7.3 15.0 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Peptidase_S8 PF00082.17 CDJ63650.1 - 0.035 13.2 2.1 0.043 12.9 1.5 1.1 1 0 0 1 1 1 0 Subtilase family MelC1 PF06236.6 CDJ63650.1 - 0.078 12.9 10.2 0.12 12.3 7.1 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 DUF3597 PF12200.3 CDJ63650.1 - 0.21 11.9 5.5 0.37 11.1 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) SR-25 PF10500.4 CDJ63651.1 - 0.011 15.2 32.5 0.013 15.0 12.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DDHD PF02862.12 CDJ63651.1 - 0.5 10.1 5.2 0.61 9.8 3.6 1.1 1 0 0 1 1 1 0 DDHD domain Dehydrin PF00257.14 CDJ63651.1 - 0.68 10.2 5.4 0.5 10.6 0.2 2.1 2 0 0 2 2 2 0 Dehydrin DUF3446 PF11928.3 CDJ63651.1 - 0.76 10.0 25.2 1.3 9.3 6.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) DNA_pol_viral_N PF00242.12 CDJ63651.1 - 9.3 5.1 11.4 0.54 9.2 3.0 1.9 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Pyr_redox PF00070.22 CDJ63653.1 - 0.00013 22.3 0.8 0.00025 21.3 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF515 PF04415.7 CDJ63653.1 - 0.028 12.6 25.2 0.034 12.4 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2453 PF10507.4 CDJ63653.1 - 0.16 11.7 1.2 0.2 11.4 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) NAD_binding_8 PF13450.1 CDJ63653.1 - 0.41 10.6 2.1 10 6.2 0.2 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pex14_N PF04695.8 CDJ63653.1 - 0.63 10.0 14.2 4 7.4 9.8 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 CDJ63653.1 - 0.74 8.0 26.0 0.8 7.9 18.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Sec3_C PF09763.4 CDJ63653.1 - 1.1 7.3 6.4 1.1 7.2 4.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Raftlin PF15250.1 CDJ63653.1 - 1.2 7.5 6.1 1.5 7.2 4.2 1.1 1 0 0 1 1 1 0 Raftlin DUF2217 PF10265.4 CDJ63653.1 - 2.2 6.9 20.5 3 6.5 14.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Apt1 PF10351.4 CDJ63653.1 - 5.2 5.8 16.1 6.2 5.5 11.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pol_alpha_B_N PF08418.5 CDJ63653.1 - 7.7 5.9 14.9 13 5.1 10.2 1.7 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pap_E4 PF02711.9 CDJ63654.1 - 0.47 11.3 2.5 0.8 10.5 1.7 1.3 1 0 0 1 1 1 0 E4 protein DUF755 PF05501.6 CDJ63654.1 - 2.5 8.1 20.4 3.3 7.7 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2217 PF10265.4 CDJ63654.1 - 8.3 5.0 9.5 9.9 4.7 6.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) HEAT PF02985.17 CDJ63656.1 - 0.00042 20.1 8.3 5.3 7.3 0.1 6.2 4 0 0 4 4 4 2 HEAT repeat Suf PF05843.9 CDJ63656.1 - 0.0015 18.3 3.1 0.0015 18.3 2.2 7.6 6 1 1 8 8 8 1 Suppressor of forked protein (Suf) SprA-related PF12118.3 CDJ63656.1 - 0.0035 16.7 29.8 0.0035 16.7 20.6 10.7 9 3 0 9 9 9 1 SprA-related family Dehydrin PF00257.14 CDJ63656.1 - 0.0037 17.6 5.1 0.0037 17.6 3.6 9.5 8 3 0 8 8 8 1 Dehydrin FimP PF09766.4 CDJ63656.1 - 0.0045 16.1 13.0 0.0045 16.1 9.0 8.0 6 2 0 6 6 6 1 Fms-interacting protein PIG-U PF06728.8 CDJ63656.1 - 1 8.1 0.8 4.4 6.0 0.0 2.5 3 1 0 3 3 3 0 GPI transamidase subunit PIG-U TIP49 PF06068.8 CDJ63657.1 - 1.8e-114 382.5 1.8 2.6e-99 332.6 0.1 3.1 2 1 1 3 3 3 3 TIP49 C-terminus CDK2AP PF09806.4 CDJ63657.1 - 0.00014 22.1 18.3 0.0035 17.6 5.0 2.2 2 0 0 2 2 2 2 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.8 CDJ63657.1 - 0.00081 18.3 3.7 0.0013 17.6 2.5 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Dehydrin PF00257.14 CDJ63657.1 - 0.0063 16.8 5.7 0.011 16.0 0.4 2.4 2 0 0 2 2 2 1 Dehydrin AAA_14 PF13173.1 CDJ63657.1 - 0.015 15.1 0.1 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain APC_CDC26 PF10471.4 CDJ63657.1 - 0.024 15.3 10.1 0.024 15.3 7.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 SR-25 PF10500.4 CDJ63657.1 - 0.09 12.2 33.5 0.58 9.5 10.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ63657.1 - 0.11 12.5 32.0 0.96 9.5 11.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) GN3L_Grn1 PF08701.6 CDJ63657.1 - 0.15 12.0 5.6 0.37 10.7 3.9 1.6 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase DUF4557 PF15101.1 CDJ63657.1 - 0.8 9.5 6.8 0.94 9.2 3.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Herpes_capsid PF06112.6 CDJ63657.1 - 1.4 8.9 17.5 1.1 9.3 2.4 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein FimP PF09766.4 CDJ63657.1 - 3.1 6.7 12.0 6.4 5.7 8.3 1.4 1 0 0 1 1 1 0 Fms-interacting protein FCP1_C PF09309.5 CDJ63657.1 - 3.6 6.8 10.9 8.4 5.6 7.5 1.5 1 0 0 1 1 1 0 FCP1, C-terminal Macoilin PF09726.4 CDJ63658.1 - 2.5 6.2 5.9 3.9 5.6 4.1 1.3 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 CDJ63658.1 - 6.5 6.1 14.2 27 4.1 9.9 2.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 CDJ63659.1 - 0.00095 19.2 3.6 0.00095 19.2 2.5 8.1 5 2 1 6 6 6 2 Gammaherpesvirus capsid protein Cpn10 PF00166.16 CDJ63662.1 - 3e-33 113.6 0.1 2.3e-17 62.6 0.0 2.3 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit Cupin_3 PF05899.7 CDJ63662.1 - 0.024 14.0 0.3 0.23 10.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF861) Med3 PF11593.3 CDJ63662.1 - 1.5 7.9 16.0 1.9 7.6 11.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.4 CDJ63662.1 - 3.4 7.0 8.1 5.4 6.4 5.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Na_H_Exchanger PF00999.16 CDJ63663.1 - 1.1e-12 47.1 10.0 1.1e-12 47.1 6.9 2.3 1 1 1 2 2 2 1 Sodium/hydrogen exchanger family Ribosomal_60s PF00428.14 CDJ63663.1 - 0.16 12.4 7.8 0.41 11.0 5.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein CRPA PF05745.6 CDJ63663.1 - 0.2 11.4 2.1 0.21 11.3 0.5 1.7 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Menin PF05053.8 CDJ63663.1 - 1.2 7.1 5.5 1.6 6.7 3.8 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 CDJ63663.1 - 6.3 4.9 19.4 8.7 4.4 13.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Flavi_DEAD PF07652.9 CDJ63665.1 - 0.073 12.8 0.9 0.21 11.3 0.2 2.0 1 1 1 2 2 2 0 Flavivirus DEAD domain SPARC_Ca_bdg PF10591.4 CDJ63665.1 - 7.6 6.5 8.9 1.3 9.1 0.1 2.9 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PPTA PF01239.17 CDJ63666.1 - 3.2e-07 29.3 13.1 0.054 12.8 0.0 4.7 4 1 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat SAPS PF04499.10 CDJ63666.1 - 0.0019 16.9 12.5 0.0019 16.9 8.7 2.3 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein DUF605 PF04652.11 CDJ63666.1 - 0.12 11.7 39.3 0.02 14.2 19.4 2.3 2 0 0 2 2 2 0 Vta1 like Anoctamin PF04547.7 CDJ63666.1 - 5.3 5.5 14.0 1.4 7.4 3.5 2.2 2 0 0 2 2 2 0 Calcium-activated chloride channel Peptidase_S49_N PF08496.5 CDJ63667.1 - 0.07 12.9 5.1 0.14 11.9 3.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4614 PF15391.1 CDJ63667.1 - 0.33 10.7 14.8 0.093 12.4 6.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 CDJ63667.1 - 0.9 8.3 10.3 0.15 10.9 3.2 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Takusan PF04822.8 CDJ63668.1 - 0.024 14.3 2.0 0.031 14.0 0.0 2.0 2 0 0 2 2 2 0 Takusan XisH PF08814.5 CDJ63668.1 - 1.5 8.8 5.0 0.16 11.9 0.2 1.7 2 0 0 2 2 2 0 XisH protein MFS_1 PF07690.11 CDJ63669.1 - 2.8e-08 32.8 13.3 2.8e-08 32.8 9.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily O-antigen_lig PF13425.1 CDJ63669.1 - 0.15 12.0 3.0 18 5.3 1.0 3.2 3 0 0 3 3 3 0 O-antigen ligase like membrane protein Neur_chan_memb PF02932.11 CDJ63669.1 - 0.15 11.9 6.9 0.37 10.6 1.1 2.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.15 CDJ63669.1 - 1.6 6.6 11.2 2.2 6.2 0.0 3.4 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Gti1_Pac2 PF09729.4 CDJ63669.1 - 3.3 7.5 8.0 6.4 6.6 1.0 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family SPX PF03105.14 CDJ63669.1 - 5.4 6.7 25.1 0.036 13.8 1.7 2.5 2 1 0 2 2 2 0 SPX domain Ribosomal_L13 PF00572.13 CDJ63670.1 - 7.4e-19 68.0 0.1 2.3e-14 53.5 0.0 3.6 4 0 0 4 4 4 3 Ribosomal protein L13 NUMOD1 PF07453.8 CDJ63671.1 - 0.0012 18.6 1.5 0.79 9.6 0.0 2.4 2 0 0 2 2 2 2 NUMOD1 domain TAP_C PF03943.8 CDJ63671.1 - 0.034 13.5 1.8 0.051 13.0 0.2 2.0 1 1 2 3 3 3 0 TAP C-terminal domain RRF_GI PF12614.3 CDJ63671.1 - 0.047 13.5 0.3 0.054 13.3 0.2 1.1 1 0 0 1 1 1 0 Ribosome recycling factor BrkDBD PF09607.5 CDJ63671.1 - 0.05 13.1 0.8 1.7 8.2 0.1 2.3 1 1 1 2 2 2 0 Brinker DNA-binding domain HTH_Mga PF08280.6 CDJ63671.1 - 0.058 13.1 0.1 0.76 9.5 0.0 2.0 1 1 1 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_Tnp_ISL3 PF13542.1 CDJ63671.1 - 0.11 11.6 0.0 1.9 7.7 0.0 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 2-Hacid_dh_C PF02826.14 CDJ63673.1 - 1.7e-30 105.4 0.0 2e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rod_cone_degen PF15201.1 CDJ63675.1 - 0.5 10.2 2.0 1.1 9.2 1.4 1.5 1 0 0 1 1 1 0 Progressive rod-cone degeneration RRM_1 PF00076.17 CDJ63676.1 - 4.3e-11 42.2 0.1 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ63676.1 - 1.5e-10 40.7 0.7 3.3e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63676.1 - 7.1e-07 29.1 0.1 0.00021 21.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3371 PF11851.3 CDJ63676.1 - 0.28 11.8 12.3 0.29 11.8 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF4647 PF15504.1 CDJ63676.1 - 1.1 8.0 12.1 1.6 7.5 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF4199 PF13858.1 CDJ63676.1 - 1.2 9.0 7.4 0.14 12.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) FimP PF09766.4 CDJ63676.1 - 2.3 7.1 22.0 1 8.3 8.9 2.3 2 0 0 2 2 2 0 Fms-interacting protein PAT1 PF09770.4 CDJ63676.1 - 3.3 5.8 33.1 4.6 5.3 22.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDJ63676.1 - 7.7 6.3 7.2 12 5.6 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IPK PF03770.11 CDJ63677.1 - 1.9e-18 66.8 0.0 1.9e-17 63.5 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase RRM_1 PF00076.17 CDJ63679.1 - 1.2e-08 34.4 0.0 2.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ63679.1 - 1.5e-05 24.7 0.0 9.4e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63679.1 - 2.2e-05 24.3 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 CDJ63680.1 - 0.11 11.9 8.9 0.13 11.6 6.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein 2OG-FeII_Oxy_5 PF13759.1 CDJ63680.1 - 0.43 10.8 6.1 0.56 10.5 4.2 1.2 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase RskA PF10099.4 CDJ63680.1 - 0.9 9.2 11.4 1.1 9.0 7.9 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA GCS2 PF04107.8 CDJ63680.1 - 2.2 7.3 7.3 2.4 7.2 5.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) FAM60A PF15396.1 CDJ63680.1 - 3.3 7.3 13.3 3.9 7.1 9.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A UPF0564 PF10595.4 CDJ63680.1 - 9.9 4.9 23.7 12 4.7 16.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Presenilin PF01080.12 CDJ63680.1 - 9.9 4.8 12.6 11 4.6 8.7 1.0 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.4 CDJ63681.1 - 2.3 7.6 8.6 3.1 7.1 5.9 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.11 CDJ63683.1 - 1.3e-17 63.5 30.3 1.3e-17 63.5 21.0 3.4 2 1 1 3 3 3 1 Major Facilitator Superfamily OATP PF03137.15 CDJ63683.1 - 7.8e-08 30.8 19.8 3.5e-05 22.0 5.8 3.9 4 1 1 5 5 5 2 Organic Anion Transporter Polypeptide (OATP) family SAPS PF04499.10 CDJ63683.1 - 0.16 10.5 3.1 0.84 8.2 0.0 2.4 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein IncA PF04156.9 CDJ63684.1 - 0.00039 20.0 14.7 0.00039 20.0 10.2 5.6 3 2 1 4 4 4 1 IncA protein RRM_1 PF00076.17 CDJ63685.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ63685.1 - 6.4e-05 22.7 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APC_CDC26 PF10471.4 CDJ63685.1 - 0.0014 19.3 10.8 0.0028 18.3 7.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 RRM_6 PF14259.1 CDJ63685.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYTT PF07078.6 CDJ63685.1 - 0.027 13.7 1.7 0.034 13.4 1.2 1.1 1 0 0 1 1 1 0 Forty-two-three protein Med15 PF09606.5 CDJ63685.1 - 0.078 11.1 13.9 0.092 10.9 9.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FCP1_C PF09309.5 CDJ63685.1 - 0.11 11.8 7.2 0.14 11.4 5.0 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF2457 PF10446.4 CDJ63685.1 - 0.12 11.1 2.9 0.14 10.8 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3138 PF11336.3 CDJ63685.1 - 0.73 7.9 7.0 1 7.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4557 PF15101.1 CDJ63685.1 - 2.8 7.7 9.7 3.6 7.3 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Folliculin PF11704.3 CDJ63685.1 - 3.8 7.0 6.9 5.2 6.6 4.8 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport RAB3GAP2_N PF14655.1 CDJ63685.1 - 4.6 6.1 7.4 6.4 5.6 5.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Hamartin PF04388.7 CDJ63687.1 - 0.091 11.4 10.4 0.092 11.4 7.2 1.1 1 0 0 1 1 1 0 Hamartin protein Suf PF05843.9 CDJ63687.1 - 0.31 10.7 5.0 0.28 10.8 3.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ63687.1 - 0.98 7.5 16.3 0.9 7.6 11.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDJ63688.1 - 1e-07 31.6 51.6 0.00027 20.4 17.5 2.0 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein SseC PF04888.7 CDJ63688.1 - 9.4e-05 21.8 12.2 9.4e-05 21.8 8.4 3.0 2 1 0 2 2 1 1 Secretion system effector C (SseC) like family Draxin PF15550.1 CDJ63688.1 - 0.044 13.4 25.3 0.056 13.0 17.5 1.1 1 0 0 1 1 1 0 Draxin Tetraspannin PF00335.15 CDJ63688.1 - 0.049 12.9 4.1 0.2 10.9 2.8 1.9 1 1 0 1 1 1 0 Tetraspanin family HXXEE PF13787.1 CDJ63688.1 - 0.14 12.5 0.6 3.7 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Claudin_2 PF13903.1 CDJ63688.1 - 1.1 8.9 15.0 0.98 9.0 2.9 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1777 PF08648.7 CDJ63688.1 - 1.8 8.2 25.1 0.99 9.1 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Ndc1_Nup PF09531.5 CDJ63688.1 - 2.7 6.3 20.5 3.6 5.8 14.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup THRAP3_BCLAF1 PF15440.1 CDJ63688.1 - 4.6 5.7 44.5 0.49 8.9 13.8 2.0 1 1 1 2 2 2 0 THRAP3/BCLAF1 family DUF4614 PF15391.1 CDJ63688.1 - 6 6.5 36.0 2.7 7.7 10.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) CD99L2 PF12301.3 CDJ63688.1 - 7 6.2 20.8 1.5 8.5 7.5 2.3 2 0 0 2 2 2 0 CD99 antigen like protein 2 DUF4355 PF14265.1 CDJ63689.1 - 0.0043 16.9 6.6 0.0043 16.9 4.6 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4355) Nucleoside_tran PF01733.13 CDJ63689.1 - 0.63 9.1 0.0 0.63 9.1 0.0 2.8 2 1 0 2 2 2 0 Nucleoside transporter SR-25 PF10500.4 CDJ63690.1 - 0.0033 16.9 18.4 0.0033 16.9 12.7 4.8 3 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ63691.1 - 0.00062 19.3 18.1 0.00062 19.3 12.6 3.2 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Dsh_C PF12316.3 CDJ63691.1 - 0.0018 18.4 2.4 0.0018 18.4 1.7 2.6 2 1 0 2 2 2 1 Segment polarity protein dishevelled (Dsh) C terminal Ctr PF04145.10 CDJ63691.1 - 0.02 14.9 18.5 0.04 13.9 4.5 3.2 3 0 0 3 3 3 0 Ctr copper transporter family DUF2201_N PF13203.1 CDJ63691.1 - 0.051 12.7 0.1 0.051 12.7 0.0 3.1 3 0 0 3 3 3 0 Putative metallopeptidase domain LMBR1 PF04791.11 CDJ63691.1 - 0.13 10.8 0.0 0.45 9.0 0.0 1.7 2 1 0 2 2 2 0 LMBR1-like membrane protein CD20 PF04103.10 CDJ63691.1 - 0.38 10.6 6.6 0.72 9.7 0.2 3.1 3 0 0 3 3 3 0 CD20-like family RE_TdeIII PF09520.5 CDJ63691.1 - 0.41 9.8 10.1 0.72 9.1 7.0 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Neur_chan_memb PF02932.11 CDJ63691.1 - 3 7.6 16.2 1.2e+02 2.4 11.2 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FimP PF09766.4 CDJ63691.1 - 4.1 6.3 29.5 2.8 6.8 0.3 3.1 3 0 0 3 3 3 0 Fms-interacting protein Spc97_Spc98 PF04130.8 CDJ63692.1 - 0.00091 17.6 0.0 0.001 17.4 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family XRCC4 PF06632.7 CDJ63692.1 - 0.24 10.2 4.4 0.48 9.2 3.1 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SR-25 PF10500.4 CDJ63692.1 - 0.74 9.2 32.7 0.27 10.6 6.3 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein GED PF02212.13 CDJ63693.1 - 5.5e-22 77.4 0.1 5.5e-22 77.4 0.1 2.2 4 0 0 4 4 4 1 Dynamin GTPase effector domain Fic PF02661.13 CDJ63693.1 - 2.7 8.7 5.7 79 4.0 0.1 3.3 2 1 0 2 2 2 0 Fic/DOC family Totivirus_coat PF05518.6 CDJ63693.1 - 7.3 4.2 10.0 13 3.4 5.6 1.9 2 0 0 2 2 2 0 Totivirus coat protein zf-RanBP PF00641.13 CDJ63694.1 - 0.0017 17.4 1.7 0.0017 17.4 1.2 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others LMF1 PF06762.9 CDJ63696.1 - 2.2e-33 115.5 0.0 2e-32 112.4 0.0 2.0 1 1 0 1 1 1 1 Lipase maturation factor Abhydrolase_5 PF12695.2 CDJ63697.1 - 0.04 13.6 0.1 0.062 13.0 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PIG-U PF06728.8 CDJ63697.1 - 0.39 9.5 5.3 0.42 9.4 2.8 1.5 1 1 1 2 2 2 0 GPI transamidase subunit PIG-U Sm_multidrug_ex PF06695.6 CDJ63697.1 - 0.64 10.2 3.4 16 5.7 1.1 2.3 1 1 1 2 2 2 0 Putative small multi-drug export protein PHO4 PF01384.15 CDJ63697.1 - 1.1 7.7 5.7 1.5 7.3 4.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family Kelch_4 PF13418.1 CDJ63698.1 - 1.3e-12 47.2 0.2 0.0016 18.1 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CDJ63698.1 - 1.4e-10 40.9 0.2 0.7 10.1 0.0 7.0 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ63698.1 - 3.9e-08 33.0 1.2 1.1 9.3 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CDJ63698.1 - 5.8e-08 32.5 0.0 0.03 14.4 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CDJ63698.1 - 6.2e-07 28.9 5.0 0.11 12.2 0.2 5.4 5 0 0 5 5 5 3 Kelch motif Ras PF00071.17 CDJ63698.1 - 0.0004 19.8 0.2 0.00065 19.1 0.1 1.4 1 0 0 1 1 1 1 Ras family Kelch_1 PF01344.20 CDJ63698.1 - 0.011 15.2 0.0 1.3 8.6 0.0 3.7 4 0 0 4 4 4 0 Kelch motif Ribosomal_60s PF00428.14 CDJ63698.1 - 0.019 15.3 8.0 0.019 15.3 5.5 5.6 4 1 1 5 5 5 0 60s Acidic ribosomal protein RskA PF10099.4 CDJ63698.1 - 0.029 14.1 0.8 0.029 14.1 0.5 4.7 3 2 1 4 4 4 0 Anti-sigma-K factor rskA AP2 PF00847.15 CDJ63699.1 - 9.1e-05 22.5 1.3 9.1e-05 22.5 0.9 2.2 2 0 0 2 2 2 1 AP2 domain ETRAMP PF09716.5 CDJ63701.1 - 0.099 12.6 0.1 0.099 12.6 0.0 3.5 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Ribonuc_red_sm PF00268.16 CDJ63702.1 - 1.5e-17 63.5 0.4 2.3e-17 62.9 0.3 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF924 PF06041.6 CDJ63702.1 - 0.027 14.2 0.7 0.12 12.0 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF924) cobW PF02492.14 CDJ63703.1 - 1.6e-24 86.3 2.7 2.2e-13 50.0 0.1 3.7 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CDJ63703.1 - 2.6e-05 24.5 4.3 0.00041 20.6 2.5 3.2 2 1 0 2 2 2 1 AAA domain RAB3GAP2_N PF14655.1 CDJ63703.1 - 6.5e-05 22.1 1.1 6.5e-05 22.1 0.8 7.7 4 2 2 7 7 7 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MobB PF03205.9 CDJ63703.1 - 0.00034 20.3 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SR-25 PF10500.4 CDJ63703.1 - 0.0018 17.7 11.3 0.0018 17.7 7.8 4.8 4 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein Arch_ATPase PF01637.13 CDJ63703.1 - 0.0043 16.7 0.0 0.0094 15.6 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 CDJ63703.1 - 0.0066 16.1 0.1 0.0066 16.1 0.1 3.7 3 1 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 CDJ63703.1 - 0.0095 16.7 0.0 0.02 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CDJ63703.1 - 0.015 15.2 0.0 0.3 11.0 0.0 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 CDJ63703.1 - 0.035 13.7 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 NTPase TPR_11 PF13414.1 CDJ63704.1 - 3.2e-22 77.9 15.2 1.1e-12 47.3 0.7 4.5 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 CDJ63704.1 - 1.6e-19 68.6 3.8 3.2e-06 26.4 0.0 5.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ63704.1 - 3.9e-14 51.3 19.3 6.4e-05 22.5 0.1 6.7 8 0 0 8 8 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ63704.1 - 2e-09 36.5 0.5 0.0019 17.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ63704.1 - 6.4e-09 35.3 5.1 0.00037 20.4 0.1 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ63704.1 - 1.1e-08 35.5 0.4 2.6e-05 24.7 0.3 7.9 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ63704.1 - 1.4e-07 31.7 19.3 0.0019 18.4 0.3 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ63704.1 - 2.6e-07 30.4 14.5 8.9e-07 28.7 0.6 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ63704.1 - 8.3e-05 22.3 0.4 0.0016 18.2 0.1 5.2 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ63704.1 - 8.5e-05 22.0 6.6 0.35 10.7 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ63704.1 - 0.00026 21.3 0.0 0.093 13.4 0.0 9.5 6 3 4 11 11 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 CDJ63704.1 - 0.12 12.3 8.2 3.2 7.7 0.3 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PAT1 PF09770.4 CDJ63704.1 - 0.15 10.2 68.4 0.23 9.6 47.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.1 CDJ63705.1 - 7.4e-06 25.5 13.1 7.4e-06 25.5 9.1 3.2 4 0 0 4 4 4 1 Spore coat protein CotO Ycf1 PF05758.7 CDJ63705.1 - 0.0014 16.4 8.6 0.0014 16.4 6.0 2.6 3 0 0 3 3 3 1 Ycf1 SAPS PF04499.10 CDJ63705.1 - 0.31 9.6 31.8 0.0056 15.3 4.9 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 CDJ63706.1 - 9.5 6.0 18.0 24 4.6 3.2 3.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF221 PF02714.10 CDJ63707.1 - 0.25 10.1 0.0 0.44 9.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF221 DUF3801 PF12687.2 CDJ63708.1 - 0.35 10.4 19.4 0.56 9.7 13.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) MCM PF00493.18 CDJ63710.1 - 6.2e-129 429.5 0.1 8.3e-129 429.1 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CDJ63710.1 - 8.1e-08 32.7 0.1 4.2e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CDJ63710.1 - 1e-06 28.0 0.1 5.5e-06 25.6 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CDJ63710.1 - 0.0042 16.6 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDJ63710.1 - 0.042 13.5 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) BAG PF02179.11 CDJ63710.1 - 1.6 8.8 6.2 0.33 11.0 0.3 2.7 3 0 0 3 3 3 0 BAG domain DUF1956 PF09209.6 CDJ63711.1 - 0.043 13.7 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1956) Peptidase_C1 PF00112.18 CDJ63712.1 - 3.8e-51 174.0 1.4 5.4e-51 173.5 0.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease SSFA2_C PF14723.1 CDJ63712.1 - 0.00067 19.4 0.0 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 Sperm-specific antigen 2 C-terminus Propeptide_C1 PF08127.8 CDJ63712.1 - 0.0031 17.0 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide HemY_N PF07219.8 CDJ63713.1 - 0.037 13.5 0.4 0.089 12.3 0.3 1.6 1 0 0 1 1 1 0 HemY protein N-terminus RNB PF00773.14 CDJ63715.1 - 1.3e-26 93.7 0.1 5.3e-26 91.6 0.0 1.9 1 1 1 2 2 2 1 RNB domain SR-25 PF10500.4 CDJ63715.1 - 0.00038 19.9 43.0 0.0095 15.4 11.7 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein OB_RNB PF08206.6 CDJ63715.1 - 0.054 13.0 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain FlgH PF02107.11 CDJ63715.1 - 0.1 12.1 5.0 0.22 11.1 3.5 1.6 1 1 0 1 1 1 0 Flagellar L-ring protein DUF3446 PF11928.3 CDJ63715.1 - 0.12 12.5 32.1 0.1 12.7 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Chorion_2 PF03964.10 CDJ63715.1 - 0.13 12.7 11.9 1.5 9.3 0.7 2.3 2 0 0 2 2 2 0 Chorion family 2 Secretin_N_2 PF07655.8 CDJ63715.1 - 0.33 11.3 22.4 0.31 11.4 3.8 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3633 PF12315.3 CDJ63715.1 - 0.41 9.9 12.2 0.045 13.0 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) DUF4551 PF15087.1 CDJ63715.1 - 1.1 7.5 8.5 1.5 7.1 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Apt1 PF10351.4 CDJ63715.1 - 1.4 7.7 16.4 2.3 6.9 11.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.5 CDJ63715.1 - 4.9 5.4 7.8 6.5 5.0 5.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IF-2B PF01008.12 CDJ63716.1 - 1.1 8.2 7.3 1.3 7.9 5.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family Trp_oprn_chp PF09534.5 CDJ63716.1 - 1.4 8.4 8.9 1.8 8.1 6.2 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SDH_beta PF03315.10 CDJ63716.1 - 2.1 8.3 8.0 3.9 7.4 5.4 1.5 1 1 1 2 2 2 0 Serine dehydratase beta chain SeqA PF03925.8 CDJ63716.1 - 4.3 6.9 20.3 1.4 8.6 7.7 2.0 2 0 0 2 2 2 0 SeqA protein Herpes_UL87 PF03043.9 CDJ63716.1 - 5.9 5.1 12.0 6.5 5.0 8.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Presenilin PF01080.12 CDJ63716.1 - 7.4 5.2 13.8 8.1 5.1 9.6 1.0 1 0 0 1 1 1 0 Presenilin COPI_assoc PF08507.5 CDJ63717.1 - 1.1e-06 28.4 0.6 2.3e-06 27.3 0.5 1.5 1 1 0 1 1 1 1 COPI associated protein Ribosomal_60s PF00428.14 CDJ63717.1 - 1.6 9.2 16.0 4.4 7.7 11.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Enkurin PF13864.1 CDJ63718.1 - 4.8e-23 81.2 0.3 4.8e-23 81.2 0.2 2.1 2 0 0 2 2 2 1 Calmodulin-binding DUF4366 PF14283.1 CDJ63719.1 - 4e-05 23.1 1.1 5.4e-05 22.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF4199 PF13858.1 CDJ63719.1 - 0.0075 16.2 3.5 0.0075 16.2 2.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) Pyocin_S PF06958.7 CDJ63719.1 - 0.024 14.9 2.5 0.036 14.4 1.8 1.2 1 0 0 1 1 1 0 S-type Pyocin Complex1_LYR PF05347.10 CDJ63719.1 - 0.032 14.0 2.0 0.17 11.6 0.2 2.8 2 1 0 2 2 2 0 Complex 1 protein (LYR family) Iron_permease PF04120.7 CDJ63719.1 - 0.036 13.6 2.3 0.051 13.1 1.6 1.3 1 0 0 1 1 1 0 Low affinity iron permease Pex16 PF08610.5 CDJ63719.1 - 0.043 12.8 6.5 0.048 12.6 4.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF970 PF06153.6 CDJ63719.1 - 0.065 13.1 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF970) DUF2849 PF11011.3 CDJ63719.1 - 0.083 13.1 0.8 0.16 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) DUF4228 PF14009.1 CDJ63719.1 - 0.11 12.6 3.4 0.15 12.1 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Suf PF05843.9 CDJ63719.1 - 0.37 10.4 9.3 0.46 10.1 6.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 CDJ63719.1 - 0.76 8.4 3.1 0.83 8.2 2.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SKI PF01202.17 CDJ63719.1 - 0.8 9.5 5.0 0.49 10.2 1.7 1.7 1 1 1 2 2 2 0 Shikimate kinase PAT1 PF09770.4 CDJ63719.1 - 2.3 6.3 27.6 2.5 6.2 19.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.9 CDJ63719.1 - 2.9 7.4 6.1 2.9 7.4 3.7 1.3 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus APC_CDC26 PF10471.4 CDJ63719.1 - 3.1 8.6 19.7 0.44 11.3 10.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF788 PF05620.6 CDJ63719.1 - 3.8 7.3 5.9 5.6 6.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) AAA_23 PF13476.1 CDJ63719.1 - 4.1 7.6 14.0 5.7 7.2 9.7 1.2 1 0 0 1 1 1 0 AAA domain Rsc14 PF08586.5 CDJ63719.1 - 5.8 7.4 13.0 14 6.2 5.8 2.1 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit tRNA-synt_1b PF00579.20 CDJ63720.1 - 1.4e-44 152.4 0.0 1.8e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Gag_p10 PF02337.12 CDJ63720.1 - 0.11 12.2 0.1 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein PP2C PF00481.16 CDJ63722.1 - 5.2e-19 68.6 0.1 5.2e-19 68.6 0.1 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 CDJ63722.1 - 0.012 15.3 0.1 0.012 15.3 0.1 1.5 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF3571 PF12095.3 CDJ63722.1 - 0.049 13.8 0.2 0.049 13.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) AAA_23 PF13476.1 CDJ63722.1 - 0.45 10.8 6.5 0.61 10.3 4.5 1.2 1 0 0 1 1 1 0 AAA domain MCPVI PF02993.9 CDJ63722.1 - 0.53 10.3 10.7 0.74 9.9 7.4 1.1 1 0 0 1 1 1 0 Minor capsid protein VI PDGF PF00341.12 CDJ63722.1 - 2.8 8.1 8.8 0.81 9.8 0.2 2.9 2 1 0 2 2 2 0 PDGF/VEGF domain DUF2756 PF10956.3 CDJ63722.1 - 8.3 6.7 33.1 1.5 9.1 15.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) MFS_1 PF07690.11 CDJ63723.1 - 1.2e-14 53.7 14.3 1.2e-14 53.7 9.9 5.7 4 2 1 6 6 6 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CDJ63723.1 - 6.3e-11 41.5 9.4 1.1e-08 34.0 0.0 2.7 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 CDJ63723.1 - 5.3e-08 31.3 3.2 2.9e-05 22.3 0.1 6.2 4 2 3 7 7 7 3 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.8 CDJ63723.1 - 0.0013 18.7 7.6 0.0013 18.7 5.3 10.6 5 3 1 6 6 6 1 Peroxisomal membrane anchor protein (Pex14p) conserved region 7tm_1 PF00001.16 CDJ63723.1 - 0.25 10.4 6.2 1 8.4 0.0 3.6 4 1 0 4 4 4 0 7 transmembrane receptor (rhodopsin family) ETRAMP PF09716.5 CDJ63723.1 - 0.9 9.5 0.0 0.9 9.5 0.0 8.1 10 0 0 10 10 10 0 Malarial early transcribed membrane protein (ETRAMP) DUF3278 PF11683.3 CDJ63724.1 - 0.33 10.9 0.1 1.1 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) AF-4 PF05110.8 CDJ63725.1 - 1.7e-05 22.9 12.1 1.7e-05 22.9 8.4 4.0 2 1 2 4 4 4 1 AF-4 proto-oncoprotein DUF937 PF06078.6 CDJ63726.1 - 2.9 8.1 15.0 11 6.2 10.4 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Adap_comp_sub PF00928.16 CDJ63727.1 - 3.4e-50 170.5 0.0 4.6e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ribosomal_60s PF00428.14 CDJ63727.1 - 0.017 15.5 7.1 0.017 15.5 5.0 3.2 3 1 0 3 3 3 0 60s Acidic ribosomal protein CDK2AP PF09806.4 CDJ63727.1 - 0.025 14.8 0.1 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDJ63728.1 - 0.0078 16.5 28.6 0.06 13.7 5.0 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein TFIIA PF03153.8 CDJ63728.1 - 0.0079 16.1 7.7 0.0094 15.8 5.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3617 PF12276.3 CDJ63728.1 - 0.0098 15.3 5.3 0.0098 15.3 3.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3617) Med15 PF09606.5 CDJ63728.1 - 0.25 9.5 18.9 0.35 9.0 13.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDJ63728.1 - 3.4 7.7 9.4 3.3 7.7 1.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Shadoo PF14999.1 CDJ63729.1 - 0.74 9.6 29.1 0.64 9.8 10.7 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDJ63729.1 - 3.5 8.0 42.2 3.9 7.9 9.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein PCI PF01399.22 CDJ63730.1 - 1.8e-15 57.1 0.1 2.9e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 PCI domain PIGA PF08288.7 CDJ63731.1 - 3.5e-38 129.8 3.7 8.2e-38 128.6 2.6 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CDJ63731.1 - 1.9e-25 89.2 0.0 3.1e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CDJ63731.1 - 1.1e-15 57.8 3.0 1.9e-15 56.9 2.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CDJ63731.1 - 1.5e-15 57.6 0.6 1.5e-14 54.4 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CDJ63731.1 - 2.4e-12 47.1 0.0 4.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CDJ63731.1 - 6.5e-08 32.5 0.9 1.1e-07 31.7 0.7 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CDJ63731.1 - 1.6e-05 25.0 0.1 4.4e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 CKS PF01111.14 CDJ63732.1 - 3.4e-19 68.4 0.0 6.9e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PP2C PF00481.16 CDJ63734.1 - 1.6e-37 129.3 0.0 2.2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CDJ63734.1 - 2.7e-06 26.9 0.0 2.1e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CDJ63734.1 - 0.022 14.4 0.0 0.23 11.1 0.0 2.3 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) YjgF_endoribonc PF14588.1 CDJ63734.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Peptidase_C2 PF00648.16 CDJ63735.1 - 2.2e-30 105.6 0.0 6.6e-27 94.2 0.0 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.17 CDJ63735.1 - 1.4e-16 60.4 2.6 1.5e-08 34.3 0.1 3.9 3 1 1 4 4 4 3 Calpain large subunit, domain III Gpi16 PF04113.9 CDJ63736.1 - 1.1e-25 89.6 0.0 2e-17 62.4 0.0 2.8 2 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component MutS_V PF00488.16 CDJ63739.1 - 3.1e-88 295.1 0.6 1.3e-87 293.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 CDJ63739.1 - 1.3e-22 80.6 1.3 1.3e-22 80.6 0.9 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CDJ63739.1 - 0.00019 21.5 2.2 0.00023 21.2 0.1 2.1 2 0 0 2 2 2 1 MutS family domain IV DUF2580 PF10824.3 CDJ63739.1 - 0.28 11.5 6.2 0.77 10.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2580) MMS19_N PF14500.1 CDJ63740.1 - 1.4e-23 83.5 0.0 1.4e-23 83.5 0.0 2.1 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II BAF1_ABF1 PF04684.8 CDJ63740.1 - 0.002 17.0 6.0 0.002 17.0 4.2 5.7 5 0 0 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor RRM_1 PF00076.17 CDJ63741.1 - 8.5e-15 54.1 0.1 1.9e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63741.1 - 3.9e-11 42.7 0.0 8.8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ63741.1 - 0.00017 21.3 0.0 0.00052 19.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SGT1 PF07093.6 CDJ63741.1 - 0.038 12.3 9.9 0.045 12.1 6.8 1.0 1 0 0 1 1 1 0 SGT1 protein Spore_coat_CotO PF14153.1 CDJ63741.1 - 0.26 10.7 13.2 1.3 8.3 3.5 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Ctr PF04145.10 CDJ63741.1 - 1.4 9.0 6.2 16 5.5 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family BSMAP PF12280.3 CDJ63741.1 - 2.5 7.9 9.0 3.9 7.3 2.9 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein FAM176 PF14851.1 CDJ63741.1 - 3.9 7.1 9.9 7.6 6.2 0.7 2.4 2 0 0 2 2 2 0 FAM176 family DUF3449 PF11931.3 CDJ63741.1 - 7.7 5.9 14.2 3.8 6.9 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Rtf2 PF04641.7 CDJ63741.1 - 8.7 5.4 19.9 2.9 7.0 7.5 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger OKR_DC_1 PF01276.15 CDJ63743.1 - 2.4e-74 250.3 0.0 3.4e-53 180.6 0.0 2.2 1 1 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 CDJ63743.1 - 0.00084 18.5 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1_C PF03711.10 CDJ63743.1 - 0.0093 16.0 0.1 0.02 14.9 0.1 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain PrmA PF06325.8 CDJ63744.1 - 4.7e-11 42.3 0.2 9.1e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CDJ63744.1 - 3.7e-10 40.3 0.1 1.2e-09 38.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDJ63744.1 - 8.5e-09 35.0 0.1 1.7e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CDJ63744.1 - 9.5e-08 31.7 0.0 2.6e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ63744.1 - 7.2e-07 29.2 0.2 7.2e-07 29.2 0.1 2.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ63744.1 - 1.8e-05 24.5 0.2 7.7e-05 22.4 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ63744.1 - 2.5e-05 24.6 0.0 0.0001 22.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ63744.1 - 0.00011 22.4 0.0 0.00045 20.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 CDJ63744.1 - 0.00031 19.9 0.0 0.00058 19.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 CDJ63744.1 - 0.00094 18.6 0.1 0.0017 17.7 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 CDJ63744.1 - 0.0013 17.8 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 CDJ63744.1 - 0.0023 17.6 0.0 0.0065 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CDJ63744.1 - 0.0026 16.5 0.2 0.0086 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) PCMT PF01135.14 CDJ63744.1 - 0.0054 16.2 0.1 0.0094 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 CDJ63744.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 CDJ63744.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.13 CDJ63744.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 CDJ63744.1 - 0.1 13.0 0.0 0.49 10.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain zf-HIT PF04438.11 CDJ63745.1 - 4.6e-05 22.9 14.0 4.6e-05 22.9 9.7 1.8 2 0 0 2 2 2 1 HIT zinc finger Methyltransf_23 PF13489.1 CDJ63746.1 - 3.2e-13 49.7 0.0 9.6e-13 48.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ63746.1 - 6.6e-10 39.3 0.0 0.00011 22.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ63746.1 - 4.7e-07 30.3 0.0 0.00022 21.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ63746.1 - 6e-06 26.6 0.0 0.048 14.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ63746.1 - 3.1e-05 23.9 2.8 0.00016 21.6 1.9 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ63746.1 - 8.2e-05 22.2 0.0 0.021 14.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ63746.1 - 0.00025 21.3 0.2 0.47 10.8 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_2 PF00891.13 CDJ63746.1 - 0.00051 19.3 0.0 0.0045 16.2 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase MTS PF05175.9 CDJ63746.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 CDJ63746.1 - 0.022 13.7 0.0 0.084 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase DUF3273 PF11677.3 CDJ63748.1 - 3.9e-74 249.2 5.3 4.5e-74 249.0 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2568 PF10823.3 CDJ63748.1 - 0.007 16.5 1.2 0.021 15.0 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2568) Exo_endo_phos PF03372.18 CDJ63750.1 - 1.2e-08 35.2 0.0 2.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EamA PF00892.15 CDJ63751.1 - 0.0083 16.1 8.5 0.0083 16.1 5.9 2.3 2 1 1 3 3 3 1 EamA-like transporter family TPT PF03151.11 CDJ63751.1 - 0.21 11.2 17.1 0.44 10.1 9.6 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family TPR_16 PF13432.1 CDJ63752.1 - 0.00096 19.7 0.1 0.00096 19.7 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ63752.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDJ63752.1 - 0.029 14.0 1.8 4 7.1 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.1 CDJ63752.1 - 0.042 14.0 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.23 CDJ63752.1 - 0.1 12.8 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 SET domain TPR_14 PF13428.1 CDJ63752.1 - 0.76 10.5 7.2 4.4 8.2 0.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.2 CDJ63753.1 - 7.1e-20 71.1 0.8 8.9e-19 67.6 0.6 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ63753.1 - 5.4e-17 60.6 11.0 3.8e-07 29.5 1.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 CDJ63753.1 - 1.2e-15 57.5 3.2 5.6e-09 36.2 0.3 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ63753.1 - 4.4e-11 41.9 3.5 0.022 14.9 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CDJ63753.1 - 1.8e-09 37.5 4.4 2.3e-06 27.6 0.4 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) CRAL_TRIO_2 PF13716.1 CDJ63754.1 - 7.3e-16 58.4 0.1 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.16 CDJ63754.1 - 2.2e-07 30.7 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Macro domain Abhydrolase_5 PF12695.2 CDJ63755.1 - 8.1e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ63755.1 - 1e-06 28.8 0.4 1.6e-05 24.8 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ63755.1 - 1.2e-05 25.0 0.1 2.5e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CDJ63755.1 - 4.7e-05 23.0 0.0 0.00081 19.0 0.0 2.4 2 0 0 2 2 2 1 Lipase (class 3) Borrelia_REV PF03978.8 CDJ63755.1 - 0.16 11.7 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein HOOK PF05622.7 CDJ63756.1 - 0.026 12.3 33.8 0.23 9.2 13.9 2.4 1 1 1 2 2 2 0 HOOK protein Shugoshin_N PF07558.6 CDJ63756.1 - 0.28 10.9 6.6 0.66 9.7 0.3 3.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Pkinase PF00069.20 CDJ63757.1 - 2.8e-63 213.5 5.5 3e-39 134.7 0.0 3.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63757.1 - 1e-25 90.2 0.0 1e-25 90.2 0.0 3.5 4 0 0 4 4 4 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CDJ63757.1 - 0.31 9.7 0.6 0.52 9.0 0.4 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MCM PF00493.18 CDJ63757.1 - 4.6 5.9 13.4 3.9 6.1 5.1 2.3 2 0 0 2 2 2 0 MCM2/3/5 family PP2C PF00481.16 CDJ63758.1 - 9.5e-32 110.3 0.0 3e-31 108.7 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3595 PF12166.3 CDJ63758.1 - 0.045 12.5 0.9 0.071 11.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) PP2C_2 PF13672.1 CDJ63758.1 - 0.064 12.6 0.1 0.064 12.6 0.0 3.3 3 2 0 3 3 3 0 Protein phosphatase 2C Rifin_STEVOR PF02009.11 CDJ63758.1 - 0.91 9.1 2.2 1.6 8.3 0.0 2.5 4 0 0 4 4 4 0 Rifin/stevor family FAST_1 PF06743.10 CDJ63759.1 - 0.047 13.4 2.6 0.49 10.1 0.6 3.0 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Candida_ALS_N PF11766.3 CDJ63760.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding RRM_1 PF00076.17 CDJ63761.1 - 8.2e-13 47.7 0.0 1.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63761.1 - 9.8e-08 31.8 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ63761.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1675 PF07897.6 CDJ63762.1 - 0.75 9.6 10.0 1.1 9.0 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) GEMIN8 PF15348.1 CDJ63762.1 - 1.4 8.9 8.8 3 7.8 0.2 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Daxx PF03344.10 CDJ63762.1 - 2.9 6.2 18.3 3.6 5.9 12.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF1180 PF06679.7 CDJ63762.1 - 3.3 7.5 6.0 9.3 6.1 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SRP-alpha_N PF04086.8 CDJ63762.1 - 3.7 6.8 12.8 4.9 6.4 8.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Herpes_capsid PF06112.6 CDJ63762.1 - 7.2 6.6 16.6 1.7 8.6 8.7 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein R3H-assoc PF13902.1 CDJ63763.1 - 0.044 13.7 3.1 0.2 11.6 0.0 3.1 3 0 0 3 3 3 0 R3H-associated N-terminal domain BAF1_ABF1 PF04684.8 CDJ63763.1 - 0.27 10.0 17.9 0.0076 15.1 4.0 2.8 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor RNase_H2-Ydr279 PF09468.5 CDJ63765.1 - 0.014 14.6 14.5 0.02 14.1 10.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 CDJ63765.1 - 0.019 14.9 6.3 0.019 14.9 4.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SR-25 PF10500.4 CDJ63765.1 - 0.093 12.1 21.7 0.12 11.8 15.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDHD PF02862.12 CDJ63765.1 - 0.16 11.7 2.5 0.17 11.6 1.7 1.2 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 CDJ63765.1 - 0.25 11.3 18.3 0.33 10.9 12.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 CDJ63765.1 - 0.33 10.0 6.0 0.39 9.8 4.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1943 PF09172.6 CDJ63765.1 - 0.53 9.0 5.3 0.7 8.7 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Paramyxo_ncap PF00973.14 CDJ63765.1 - 0.7 8.5 4.4 0.76 8.3 3.1 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.7 CDJ63765.1 - 0.71 9.7 8.6 0.8 9.5 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 CDJ63765.1 - 0.85 9.0 16.3 0.98 8.8 11.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HSP90 PF00183.13 CDJ63765.1 - 2.2 6.5 15.4 2.8 6.2 10.7 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF1168 PF06658.7 CDJ63765.1 - 3 7.3 25.4 4.6 6.7 17.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) YqfQ PF14181.1 CDJ63765.1 - 3.2 7.7 14.8 5.3 7.0 10.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein NARP1 PF12569.3 CDJ63765.1 - 4.8 5.8 18.7 5.8 5.5 13.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4473 PF14747.1 CDJ63766.1 - 0.046 13.9 3.4 0.091 12.9 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Striatin PF08232.7 CDJ63766.1 - 0.11 12.7 7.5 0.18 12.1 5.2 1.3 1 0 0 1 1 1 0 Striatin family TSGP1 PF07771.6 CDJ63766.1 - 0.56 10.1 5.4 0.86 9.5 3.7 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 DUF106 PF01956.11 CDJ63766.1 - 0.6 9.6 2.0 0.76 9.2 1.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 HR1 PF02185.11 CDJ63767.1 - 0.092 12.5 0.3 9 6.1 0.0 2.4 2 0 0 2 2 2 0 Hr1 repeat DUF4599 PF15371.1 CDJ63768.1 - 0.038 14.0 0.4 0.038 14.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Helicase_C_2 PF13307.1 CDJ63770.1 - 0.1 12.5 0.3 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain MADF_DNA_bdg PF10545.4 CDJ63770.1 - 0.45 10.7 4.3 0.5 10.5 1.5 2.0 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1049 PF06305.6 CDJ63770.1 - 0.9 9.0 6.3 1.4 8.4 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) RAP PF08373.5 CDJ63774.1 - 1.5e-06 27.8 0.0 5.5e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 RAP domain Ycf1 PF05758.7 CDJ63774.1 - 1.9 6.1 19.2 0.51 7.9 2.5 2.1 2 0 0 2 2 2 0 Ycf1 DUF966 PF06136.8 CDJ63774.1 - 3.3 7.0 28.5 1.3 8.4 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DUF2867 PF11066.3 CDJ63774.1 - 4.2 7.0 12.0 0.85 9.3 0.1 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2867) Filo_glycop PF01611.11 CDJ63775.1 - 3.2 6.4 22.0 3.6 6.2 15.3 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein Parvo_coat PF00740.13 CDJ63775.1 - 9.2 5.0 27.7 10 4.9 19.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF3993 PF13158.1 CDJ63776.1 - 0.21 11.4 0.0 0.77 9.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) CDK2AP PF09806.4 CDJ63777.1 - 0.00064 20.0 8.9 0.00064 20.0 6.2 2.0 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein DUF1183 PF06682.7 CDJ63777.1 - 0.0036 16.9 8.5 0.0036 16.9 5.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1183) SUZ PF12752.2 CDJ63777.1 - 0.035 14.6 3.0 0.035 14.6 2.1 2.7 3 0 0 3 3 3 0 SUZ domain Med15 PF09606.5 CDJ63777.1 - 0.052 11.7 25.7 0.067 11.3 5.2 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal GRA6 PF05084.8 CDJ63777.1 - 0.11 11.9 0.4 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF4184 PF13803.1 CDJ63777.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) DEAD PF00270.24 CDJ63778.1 - 3.6e-24 85.1 0.0 3.6e-24 85.1 0.0 3.4 3 2 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ63778.1 - 7.2e-21 73.8 0.0 7.2e-21 73.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CDJ63778.1 - 0.25 11.4 0.0 0.25 11.4 0.0 4.1 4 1 0 4 4 4 0 AAA domain Peptidase_M24 PF00557.19 CDJ63779.1 - 1.5e-19 70.4 13.0 2.9e-15 56.4 6.9 2.7 2 1 0 2 2 2 1 Metallopeptidase family M24 Med15 PF09606.5 CDJ63779.1 - 0.00063 18.1 2.9 0.00063 18.1 2.0 2.1 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal CDK2AP PF09806.4 CDJ63779.1 - 0.0056 16.9 15.5 0.23 11.6 0.0 3.3 2 1 1 3 3 3 2 Cyclin-dependent kinase 2-associated protein Porin_4 PF13609.1 CDJ63779.1 - 4.5 6.6 0.0 4.5 6.6 0.0 3.5 4 0 0 4 4 4 0 Gram-negative porin DUF755 PF05501.6 CDJ63780.1 - 0.0028 17.7 27.6 0.0038 17.2 19.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) DNA_primase_lrg PF04104.9 CDJ63780.1 - 0.023 13.9 0.2 0.03 13.6 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Herpes_capsid PF06112.6 CDJ63780.1 - 0.035 14.1 9.7 0.057 13.4 6.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GvpL_GvpF PF06386.6 CDJ63780.1 - 0.13 11.8 1.7 0.16 11.5 1.2 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3361 PF11841.3 CDJ63780.1 - 0.29 10.8 3.7 0.47 10.1 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) FA_desaturase PF00487.19 CDJ63780.1 - 0.75 9.1 2.6 1.1 8.6 1.8 1.2 1 0 0 1 1 1 0 Fatty acid desaturase AF-4 PF05110.8 CDJ63780.1 - 1.1 7.0 18.5 1.4 6.7 12.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Mcm10 PF09332.6 CDJ63780.1 - 4.9 6.4 8.7 6 6.1 6.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF2217 PF10265.4 CDJ63780.1 - 7.1 5.2 8.8 8.4 5.0 6.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DNA_pol_viral_N PF00242.12 CDJ63780.1 - 7.1 5.5 13.4 8.9 5.2 9.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Pkinase PF00069.20 CDJ63781.1 - 9.7e-25 87.1 0.1 5.5e-24 84.7 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63781.1 - 1e-12 47.6 0.1 8.8e-08 31.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDJ63781.1 - 0.0013 17.7 0.0 0.076 11.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Activator_LAG-3 PF11498.3 CDJ63781.1 - 0.033 12.9 14.7 0.057 12.1 10.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Kdo PF06293.9 CDJ63781.1 - 0.077 12.0 0.1 0.077 12.0 0.1 2.0 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3412 PF11892.3 CDJ63781.1 - 0.55 10.0 2.4 0.4 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3412) DUF572 PF04502.8 CDJ63782.1 - 0.038 13.2 16.3 0.04 13.1 11.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) FCP1_C PF09309.5 CDJ63782.1 - 0.22 10.7 10.7 0.31 10.3 7.4 1.3 1 0 0 1 1 1 0 FCP1, C-terminal RAP1 PF07218.6 CDJ63782.1 - 1.2 7.1 13.5 1.4 6.9 9.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4054 PF13262.1 CDJ63782.1 - 1.2 9.3 5.4 1.9 8.8 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4054) CAML PF14963.1 CDJ63782.1 - 1.5 8.1 6.8 1.8 7.8 4.7 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Ashwin PF15323.1 CDJ63782.1 - 1.5 8.7 15.9 1.6 8.6 11.0 1.1 1 0 0 1 1 1 0 Developmental protein MDFI PF15316.1 CDJ63782.1 - 1.6 8.6 12.9 2 8.3 8.9 1.1 1 0 0 1 1 1 0 MyoD family inhibitor MAT1 PF06391.8 CDJ63782.1 - 1.7 8.1 9.7 2.1 7.8 6.7 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Peptidase_S30 PF01577.11 CDJ63782.1 - 2.6 7.3 10.3 3.2 7.0 7.1 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Zip PF02535.17 CDJ63782.1 - 3.2 6.6 4.7 3.3 6.6 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CDJ63782.1 - 4 5.3 12.9 4.3 5.2 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 CDJ63782.1 - 7.4 4.9 14.2 8.3 4.8 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MSP1_C PF07462.6 CDJ63783.1 - 3.7 5.8 16.7 4.1 5.6 11.6 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3450 PF11932.3 CDJ63783.1 - 6.5 5.9 19.3 9.1 5.4 13.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 CDJ63789.1 - 1.1e-23 83.6 3.9 3.6e-11 42.7 0.0 3.3 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63789.1 - 1.6e-14 53.6 0.4 1.1e-06 27.9 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase PAT1 PF09770.4 CDJ63789.1 - 0.94 7.6 34.3 2.6 6.1 23.8 1.7 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDJ63789.1 - 6.5 4.3 10.4 9.4 3.8 7.2 1.1 1 0 0 1 1 1 0 Ycf1 Mmp37 PF09139.6 CDJ63789.1 - 9.3 5.1 12.0 15 4.5 8.3 1.2 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Methyltrn_RNA_4 PF09936.4 CDJ63790.1 - 0.049 13.1 3.9 0.1 12.0 2.7 1.4 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Spt20 PF12090.3 CDJ63790.1 - 8.8 5.6 26.3 0.52 9.6 1.5 3.0 3 0 0 3 3 3 0 Spt20 family Neur_chan_memb PF02932.11 CDJ63790.1 - 9 6.0 8.9 20 4.9 0.0 2.7 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region CAF-1_p150 PF11600.3 CDJ63791.1 - 0.00082 18.8 40.6 0.00082 18.8 28.2 4.0 3 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Parvo_coat PF00740.13 CDJ63791.1 - 2.4 7.0 29.2 0.13 11.1 15.1 2.0 2 0 0 2 2 2 0 Parvovirus coat protein VP2 FHIPEP PF00771.15 CDJ63791.1 - 6.4 4.9 12.9 3.8 5.7 6.1 2.2 2 0 0 2 2 2 0 FHIPEP family S-antigen PF05756.6 CDJ63791.1 - 6.6 6.7 9.5 14 5.7 6.6 1.6 1 0 0 1 1 1 0 S-antigen protein DJ-1_PfpI PF01965.19 CDJ63792.1 - 2.8e-17 62.5 0.0 7.1e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family MIF4G PF02854.14 CDJ63792.1 - 1.1e-13 51.1 0.2 8.7e-11 41.6 0.1 2.7 1 1 0 1 1 1 1 MIF4G domain DUF4066 PF13278.1 CDJ63792.1 - 1.2e-08 34.3 0.0 1.2e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Putative amidotransferase Upf2 PF04050.9 CDJ63792.1 - 3.9e-08 33.2 14.2 3.9e-08 33.2 9.8 3.3 3 0 0 3 3 2 1 Up-frameshift suppressor 2 DUF2722 PF10846.3 CDJ63792.1 - 0.022 13.7 29.8 0.49 9.3 1.4 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Phage-A118_gp45 PF10653.4 CDJ63792.1 - 0.094 12.5 0.1 16 5.4 0.0 2.4 1 1 1 2 2 2 0 Protein gp45 of Bacteriophage A118 Zn_peptidase PF04228.8 CDJ63792.1 - 1.1 8.4 15.1 0.09 11.9 0.5 3.3 3 0 0 3 3 3 0 Putative neutral zinc metallopeptidase Spt20 PF12090.3 CDJ63792.1 - 2.9 7.2 25.5 0.24 10.7 0.1 3.6 3 1 0 3 3 2 0 Spt20 family DUF4064 PF13273.1 CDJ63792.1 - 4.7 7.3 5.9 1.6 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) RAB3GAP2_N PF14655.1 CDJ63792.1 - 5.1 5.9 19.7 1.9 7.3 0.9 3.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Fes1 PF08609.5 CDJ63792.1 - 7.5 7.1 15.7 20 5.7 0.0 4.5 4 1 0 4 4 4 0 Nucleotide exchange factor Fes1 UCH PF00443.24 CDJ63794.1 - 1.2e-13 50.7 0.2 1.2e-13 50.7 0.1 6.3 6 2 1 7 7 7 2 Ubiquitin carboxyl-terminal hydrolase DUF2722 PF10846.3 CDJ63795.1 - 0.00012 21.2 0.5 0.048 12.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) DUF4378 PF14309.1 CDJ63795.1 - 0.003 17.6 0.2 0.006 16.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) Spt20 PF12090.3 CDJ63795.1 - 0.0072 15.7 7.0 0.1 11.9 1.2 2.6 3 0 0 3 3 3 2 Spt20 family RAB3GAP2_N PF14655.1 CDJ63795.1 - 1.2 8.0 15.3 1.4 7.8 0.4 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDJ63795.1 - 7.3 6.2 21.8 0.024 14.3 4.7 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Pkinase PF00069.20 CDJ63798.1 - 3.1e-46 157.6 0.0 5.8e-45 153.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ63798.1 - 1.2e-22 80.2 0.1 1.5e-15 56.9 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase FCP1_C PF09309.5 CDJ63799.1 - 0.0045 16.3 3.2 0.0045 16.3 2.2 2.8 3 0 0 3 3 3 1 FCP1, C-terminal SR-25 PF10500.4 CDJ63799.1 - 0.0066 15.9 35.3 0.021 14.2 6.7 3.3 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein PUF PF00806.14 CDJ63799.1 - 0.065 12.7 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Vps51 PF08700.6 CDJ63800.1 - 3e-18 65.4 0.7 5.3e-18 64.6 0.1 1.7 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 CDJ63800.1 - 2e-07 30.9 1.8 3.3e-07 30.2 1.3 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.7 CDJ63800.1 - 4.3e-06 25.4 2.4 5.6e-06 25.0 1.6 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 CDJ63800.1 - 4.1e-05 23.3 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 Zw10 PF06248.8 CDJ63800.1 - 0.048 11.8 0.4 0.061 11.4 0.3 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Tweety PF04906.8 CDJ63800.1 - 0.058 11.7 1.6 0.089 11.1 1.1 1.2 1 0 0 1 1 1 0 Tweety COG5 PF10392.4 CDJ63800.1 - 0.15 12.0 3.0 0.26 11.2 2.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3086 PF11285.3 CDJ63800.1 - 0.17 10.6 3.4 0.25 10.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) RVT_1 PF00078.22 CDJ63802.1 - 0.00083 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.3 CDJ63802.1 - 0.0043 16.2 0.6 0.007 15.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) RNase_H PF00075.19 CDJ63803.1 - 0.0034 17.7 0.0 0.0075 16.5 0.0 1.6 2 0 0 2 2 2 1 RNase H rve PF00665.21 CDJ63804.1 - 7.4e-19 68.0 0.0 1.9e-18 66.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 CDJ63804.1 - 0.00066 19.0 0.5 0.00066 19.0 0.4 1.8 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Laminin_G_3 PF13385.1 CDJ63806.1 - 1.6e-17 64.2 0.0 2.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CDJ63806.1 - 6.8e-07 29.3 0.2 1.8e-06 28.0 0.0 1.8 2 1 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.18 CDJ63806.1 - 9.9e-05 22.3 0.0 0.00025 21.0 0.0 1.7 1 1 0 1 1 1 1 Laminin G domain SpvB PF03534.8 CDJ63807.1 - 0.61 9.0 11.0 0.0093 15.0 2.5 1.7 2 0 0 2 2 2 0 Salmonella virulence plasmid 65kDa B protein Reo_sigmaC PF04582.7 CDJ63807.1 - 8.1 5.5 14.3 0.3 10.2 3.9 2.6 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DNA_pol_A PF00476.15 CDJ63808.1 - 1.7e-44 151.9 0.0 4.6e-40 137.4 0.0 2.5 3 0 0 3 3 3 2 DNA polymerase family A SART-1 PF03343.8 CDJ63808.1 - 0.29 9.4 4.9 0.47 8.7 3.4 1.2 1 0 0 1 1 1 0 SART-1 family V-SNARE_C PF12352.3 CDJ63809.1 - 7.5e-07 29.1 20.7 1.9e-06 27.8 0.9 3.7 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus SR-25 PF10500.4 CDJ63809.1 - 6.3e-05 22.5 5.4 6.3e-05 22.5 3.7 3.4 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Sec20 PF03908.8 CDJ63809.1 - 0.0022 17.6 1.3 0.0022 17.6 0.9 3.8 3 1 2 5 5 5 1 Sec20 DUF3446 PF11928.3 CDJ63809.1 - 0.017 15.3 7.2 0.017 15.3 5.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Dpy-30 PF05186.8 CDJ63810.1 - 5.2e-13 48.2 2.2 9.2e-13 47.4 1.5 1.4 1 0 0 1 1 1 1 Dpy-30 motif UPF0560 PF10577.4 CDJ63810.1 - 0.53 8.4 3.8 0.59 8.3 2.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 IncA PF04156.9 CDJ63811.1 - 1.9e-07 30.8 25.4 0.00046 19.8 10.1 2.1 2 0 0 2 2 2 2 IncA protein CD20 PF04103.10 CDJ63811.1 - 0.00038 20.4 3.0 0.42 10.5 0.1 2.3 2 0 0 2 2 2 2 CD20-like family DUF4557 PF15101.1 CDJ63811.1 - 0.0035 17.2 25.2 0.0035 17.2 17.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4557) VIT1 PF01988.14 CDJ63811.1 - 0.0037 16.7 9.7 0.31 10.5 4.2 2.2 2 0 0 2 2 2 2 VIT family Ycf1 PF05758.7 CDJ63811.1 - 0.0046 14.7 10.0 0.0055 14.5 6.9 1.2 1 0 0 1 1 1 1 Ycf1 DUF4179 PF13786.1 CDJ63811.1 - 0.0052 16.9 4.9 0.32 11.2 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4179) Ctr PF04145.10 CDJ63811.1 - 0.0052 16.8 12.2 0.0064 16.5 3.2 2.2 2 0 0 2 2 2 1 Ctr copper transporter family DUF1469 PF07332.6 CDJ63811.1 - 0.0061 16.2 12.4 0.084 12.6 2.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1469) DUF4367 PF14285.1 CDJ63811.1 - 0.0075 15.6 7.1 0.052 12.8 1.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4367) Shadoo PF14999.1 CDJ63811.1 - 0.0096 15.7 20.6 0.11 12.3 5.9 2.4 2 0 0 2 2 2 2 Shadow of prion protein, neuroprotective Oleosin PF01277.12 CDJ63811.1 - 0.043 13.3 13.4 0.47 10.0 0.7 2.3 2 0 0 2 2 2 0 Oleosin Vfa1 PF08432.5 CDJ63811.1 - 0.096 12.7 24.0 0.23 11.4 11.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF2231 PF09990.4 CDJ63811.1 - 0.11 12.8 9.4 0.38 11.1 0.9 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF2052 PF09747.4 CDJ63811.1 - 0.25 11.2 22.0 0.094 12.6 7.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SR-25 PF10500.4 CDJ63811.1 - 0.35 10.3 21.4 0.19 11.1 8.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SAPS PF04499.10 CDJ63811.1 - 0.43 9.1 15.4 0.56 8.7 10.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4386 PF14329.1 CDJ63811.1 - 0.48 9.8 11.5 1.4 8.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) DUF2217 PF10265.4 CDJ63811.1 - 0.66 8.6 19.4 1.1 7.9 6.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) DUF2899 PF11449.3 CDJ63811.1 - 0.73 8.9 6.5 4.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2899) FHIPEP PF00771.15 CDJ63811.1 - 0.99 7.6 18.2 0.17 10.1 4.9 2.1 2 0 0 2 2 2 0 FHIPEP family DUF3357 PF11837.3 CDJ63811.1 - 1.1 9.1 15.3 0.92 9.3 1.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) FPN1 PF06963.7 CDJ63811.1 - 1.2 7.4 8.6 0.63 8.3 1.3 2.0 2 0 0 2 2 2 0 Ferroportin1 (FPN1) CPSF100_C PF13299.1 CDJ63811.1 - 1.5 8.9 20.0 0.99 9.5 7.6 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3450 PF11932.3 CDJ63811.1 - 1.6 7.9 52.5 2.8 7.1 21.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SelP_N PF04592.9 CDJ63811.1 - 1.7 8.0 15.8 0.2 10.9 5.6 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF3807 PF12720.2 CDJ63811.1 - 1.7 8.8 27.8 0.69 10.0 10.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF2232 PF09991.4 CDJ63811.1 - 1.9 7.4 14.8 0.49 9.3 3.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) eIF-3_zeta PF05091.7 CDJ63811.1 - 3.4 6.1 30.6 0.24 10.0 11.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) U79_P34 PF03064.11 CDJ63811.1 - 3.5 7.0 20.7 0.41 10.1 8.0 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 CDJ63811.1 - 3.8 7.2 23.7 0.87 9.3 8.6 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MRP-S31 PF15433.1 CDJ63811.1 - 4 6.7 25.8 1 8.7 9.1 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 RNA_pol_Rpb1_5 PF04998.12 CDJ63811.1 - 4.8 6.3 11.9 9.2 5.4 8.3 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FLO_LFY PF01698.11 CDJ63811.1 - 4.8 5.9 25.6 0.51 9.1 9.8 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF3449 PF11931.3 CDJ63811.1 - 4.9 6.6 20.9 2.1 7.8 8.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) GAGA_bind PF06217.7 CDJ63811.1 - 5.8 6.7 22.4 1.9 8.3 8.6 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Raftlin PF15250.1 CDJ63811.1 - 6.3 5.1 20.5 0.82 8.1 7.6 2.0 2 0 0 2 2 2 0 Raftlin DUF2215 PF10225.4 CDJ63811.1 - 6.3 6.1 12.1 1.4 8.3 3.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) FimP PF09766.4 CDJ63811.1 - 6.5 5.7 44.3 4.8 6.1 7.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein GDA1_CD39 PF01150.12 CDJ63812.1 - 5e-29 101.0 0.0 3.1e-26 91.8 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF3086 PF11285.3 CDJ63813.1 - 0.091 11.5 1.9 0.1 11.3 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) ATP-synt_E PF05680.7 CDJ63813.1 - 3 7.8 8.6 5.5 7.0 6.0 1.5 1 0 0 1 1 1 0 ATP synthase E chain RNase_PH PF01138.16 CDJ63814.1 - 8.2e-10 39.0 0.0 8.2e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 zf-DHHC PF01529.15 CDJ63815.1 - 1 8.7 0.8 67 2.8 0.2 3.0 3 0 0 3 3 3 0 DHHC palmitoyltransferase Spt20 PF12090.3 CDJ63815.1 - 3.3 7.0 22.7 0.57 9.5 0.2 3.7 4 0 0 4 4 4 0 Spt20 family RRM_1 PF00076.17 CDJ63816.1 - 7.5e-15 54.3 0.0 1.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ63816.1 - 8e-12 44.9 0.0 1.9e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ63816.1 - 9.2e-08 31.8 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ctr PF04145.10 CDJ63818.1 - 4.3e-21 75.4 13.4 2.6e-19 69.7 9.3 2.1 1 1 0 1 1 1 1 Ctr copper transporter family GLTP PF08718.6 CDJ63819.1 - 1.6e-24 86.6 0.0 1.9e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Reticulon PF02453.12 CDJ63822.1 - 1.7e-10 40.7 10.1 2.2e-10 40.3 6.9 1.4 1 1 0 1 1 1 1 Reticulon 2TM PF13239.1 CDJ63822.1 - 1.1 9.3 3.7 8.3 6.5 0.1 2.3 2 0 0 2 2 2 0 2TM domain zf-PARP PF00645.13 CDJ63823.1 - 2.2e-08 34.1 0.0 6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF2217 PF10265.4 CDJ63823.1 - 0.0054 15.5 1.0 0.0068 15.2 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) SNF2_N PF00176.18 CDJ63823.1 - 0.011 14.5 0.1 0.019 13.7 0.1 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain RAP1 PF07218.6 CDJ63823.1 - 8 4.4 6.6 10 4.0 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SNF2_N PF00176.18 CDJ63824.1 - 3.9e-18 65.2 0.0 4.4e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.18 CDJ63825.1 - 1.3e-24 86.5 0.0 1.4e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CDJ63825.1 - 7.4e-14 51.3 0.0 1.8e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CDJ63825.1 - 1.9e-09 37.2 1.7 7.4e-09 35.3 1.2 2.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDJ63825.1 - 2e-05 24.6 2.2 3.3e-05 23.8 0.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDJ63825.1 - 7.5e-05 22.3 2.3 7.5e-05 22.3 1.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDJ63825.1 - 0.00061 19.5 1.0 0.0031 17.3 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CDJ63825.1 - 0.00074 19.5 1.1 0.00074 19.5 0.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CDJ63825.1 - 0.0045 16.9 0.8 0.043 13.7 0.2 2.6 2 0 0 2 2 2 1 FANCL C-terminal domain UQ_con PF00179.21 CDJ63826.1 - 2e-43 147.1 0.0 2.6e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDJ63826.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Herpes_BLLF1 PF05109.8 CDJ63826.1 - 6.1 4.6 7.8 7.8 4.3 5.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) UQ_con PF00179.21 CDJ63827.1 - 2.1e-17 62.8 0.0 3.4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDJ63827.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain WD40 PF00400.27 CDJ63828.1 - 2e-24 84.5 10.3 3.7e-08 32.9 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ PF01011.16 CDJ63828.1 - 0.0018 17.7 0.4 47 3.7 0.0 4.5 4 0 0 4 4 4 0 PQQ enzyme repeat EF-hand_1 PF00036.27 CDJ63828.1 - 0.0033 16.6 0.0 0.0075 15.4 0.0 1.6 1 0 0 1 1 1 1 EF hand eIF2A PF08662.6 CDJ63828.1 - 0.04 13.6 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4529 PF15032.1 CDJ63828.1 - 0.19 10.3 0.1 1.8 7.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4529) RCC1 PF00415.13 CDJ63829.1 - 2.3e-11 43.7 20.8 0.00011 22.2 2.6 7.3 8 1 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ63829.1 - 9e-11 41.0 27.0 0.0029 17.1 0.8 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat PDEase_I PF00233.14 CDJ63830.1 - 4.9e-45 154.1 7.3 9.6e-24 84.4 2.7 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase GAF_3 PF13492.1 CDJ63830.1 - 4.2e-05 23.6 0.0 0.00019 21.5 0.0 2.1 1 0 0 1 1 1 1 GAF domain CBM_48 PF02922.13 CDJ63831.1 - 6.4e-20 70.9 0.0 1e-18 67.1 0.0 2.9 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.13 CDJ63831.1 - 6.2e-19 67.9 0.0 2.3e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CDJ63831.1 - 6.5e-17 61.8 0.2 5.9e-08 32.4 0.0 3.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF45 PF01863.12 CDJ63832.1 - 3.6 7.3 7.8 0.74 9.5 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF45 Spore_III_AF PF09581.5 CDJ63832.1 - 8.1 6.2 7.5 0.48 10.2 0.4 2.4 3 0 0 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) OB_NTP_bind PF07717.11 CDJ63833.1 - 1.3e-14 53.9 0.0 3.7e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CDJ63833.1 - 7e-13 48.4 0.0 2.4e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CDJ63833.1 - 7.1e-12 45.0 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDJ63833.1 - 1.3e-08 34.4 0.2 2.7e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDJ63833.1 - 6.1e-05 23.1 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CDJ63833.1 - 0.0026 16.7 0.0 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CDJ63833.1 - 0.0085 15.8 0.7 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CDJ63833.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 CDJ63833.1 - 0.041 12.8 0.1 0.09 11.7 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CDJ63833.1 - 0.08 12.7 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Tyr_Deacylase PF02580.11 CDJ63834.1 - 2.5e-39 134.5 0.0 3e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase SEP PF08059.8 CDJ63834.1 - 0.072 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 SEP domain C2 PF00168.25 CDJ63835.1 - 1.5e-12 47.1 0.0 1.1e-10 41.2 0.0 3.0 2 0 0 2 2 2 2 C2 domain DUF572 PF04502.8 CDJ63836.1 - 0.22 10.7 1.0 0.43 9.7 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Bromodomain PF00439.20 CDJ63837.1 - 1.3e-08 34.6 0.0 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Citrate_synt PF00285.16 CDJ63838.1 - 8.7e-20 70.7 0.0 8.7e-20 70.7 0.0 3.2 3 1 1 4 4 4 1 Citrate synthase Ligase_CoA PF00549.14 CDJ63838.1 - 5.7e-13 48.7 0.0 5.7e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.14 CDJ63838.1 - 1.3e-06 28.7 0.0 4e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 CDJ63838.1 - 2.5e-05 23.7 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain NUDIX_2 PF13869.1 CDJ63839.1 - 0.34 10.2 3.6 0.21 10.9 0.2 2.3 2 0 0 2 2 2 0 Nucleotide hydrolase BAF1_ABF1 PF04684.8 CDJ63840.1 - 0.00013 20.9 26.0 0.00013 20.9 18.0 20.4 7 3 12 21 21 21 1 BAF1 / ABF1 chromatin reorganising factor Sugar_tr PF00083.19 CDJ63842.1 - 0.0026 16.4 0.3 0.0026 16.4 0.2 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter HlyD_2 PF12700.2 CDJ63842.1 - 1 8.4 3.6 1.1 8.3 2.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF913 PF06025.7 CDJ63842.1 - 6 5.5 6.3 3.6 6.2 3.4 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Lin-8 PF03353.10 CDJ63842.1 - 7.1 5.8 10.5 10 5.2 7.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Striatin PF08232.7 CDJ63842.1 - 7.2 6.9 10.9 6.9 6.9 6.5 1.8 1 1 1 2 2 2 0 Striatin family Sugar_tr PF00083.19 CDJ63843.1 - 3.2e-40 138.0 43.5 3.7e-24 85.1 15.7 3.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CDJ63843.1 - 7.8e-09 34.7 7.2 7.8e-09 34.7 5.0 4.0 2 2 1 3 3 3 2 Major Facilitator Superfamily GNVR PF13807.1 CDJ63843.1 - 1.5 8.5 3.8 7.9 6.3 0.0 2.8 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase EF-hand_1 PF00036.27 CDJ63844.1 - 2.3e-30 101.5 8.3 9.1e-08 30.8 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDJ63844.1 - 6.9e-25 86.9 5.4 1.5e-11 44.2 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDJ63844.1 - 2.5e-23 79.7 6.8 1e-05 24.9 0.1 5.0 5 1 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 CDJ63844.1 - 7.4e-23 78.8 9.9 7.3e-07 28.2 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CDJ63844.1 - 3.2e-18 65.0 9.8 9.7e-06 25.1 1.0 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CDJ63844.1 - 6.9e-08 32.5 1.5 0.0062 16.5 0.3 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CDJ63844.1 - 3e-07 30.1 4.9 0.00024 20.8 0.6 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 CDJ63844.1 - 2e-05 23.8 0.0 5.2e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain EF-hand_10 PF14788.1 CDJ63844.1 - 0.0013 18.3 5.0 1.5 8.5 0.0 4.1 3 1 1 4 4 4 2 EF hand EF-hand_9 PF14658.1 CDJ63844.1 - 0.011 15.6 0.1 0.99 9.3 0.0 3.0 2 1 0 2 2 2 0 EF-hand domain TerB PF05099.8 CDJ63844.1 - 0.087 12.5 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TerB Toprim_4 PF13662.1 CDJ63844.1 - 0.21 11.6 0.7 17 5.5 0.0 2.9 2 1 0 2 2 2 0 Toprim domain AlaDh_PNT_N PF05222.10 CDJ63845.1 - 7.7e-23 80.9 0.0 6.9e-13 48.7 0.0 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CDJ63845.1 - 5.9e-20 71.5 0.1 1.2e-19 70.4 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 CDJ63845.1 - 0.00018 21.7 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.9 CDJ63845.1 - 0.00067 18.2 0.4 0.0012 17.4 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 CDJ63845.1 - 0.00082 19.0 0.7 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 CDJ63845.1 - 0.0022 17.8 0.2 0.048 13.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDJ63845.1 - 0.0042 17.4 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CDJ63845.1 - 0.0055 15.6 0.6 0.0085 14.9 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CDJ63845.1 - 0.011 14.7 0.1 0.017 14.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 CDJ63845.1 - 0.023 13.5 1.2 0.037 12.8 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 CDJ63845.1 - 0.07 12.0 3.2 0.077 11.8 0.9 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase XdhC_C PF13478.1 CDJ63845.1 - 0.071 13.4 0.1 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain FAD_oxidored PF12831.2 CDJ63845.1 - 0.085 11.9 4.1 0.16 10.9 2.9 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_18 PF12847.2 CDJ63846.1 - 1e-09 38.9 0.0 9.1e-06 26.2 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ63846.1 - 3.6e-06 26.6 0.1 0.0042 16.6 0.0 3.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ63846.1 - 0.00013 22.2 0.0 0.0066 16.7 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ63846.1 - 0.00021 21.0 0.1 0.04 13.6 0.0 3.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ63846.1 - 0.00027 21.3 0.0 0.0058 17.0 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ63846.1 - 0.00062 20.2 0.0 0.019 15.4 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ63846.1 - 0.00068 19.6 0.0 1.3 9.0 0.1 3.3 3 0 0 3 3 3 2 Methyltransferase domain Spermine_synth PF01564.12 CDJ63846.1 - 0.0037 16.2 0.0 0.083 11.8 0.0 2.7 3 0 0 3 3 3 1 Spermine/spermidine synthase DEC-1_N PF04625.8 CDJ63846.1 - 0.17 10.5 4.0 0.39 9.3 2.8 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MmgE_PrpD PF03972.9 CDJ63847.1 - 3.5e-06 25.4 0.0 4.1e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF3482 PF11981.3 CDJ63847.1 - 0.055 12.6 0.9 0.066 12.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) IMCp PF12314.3 CDJ63850.1 - 4.8e-20 71.4 50.0 9.3e-14 51.3 13.5 6.4 3 2 3 6 6 6 3 Inner membrane complex protein AF-4 PF05110.8 CDJ63850.1 - 3.6e-06 25.2 8.0 4.4e-06 24.9 5.5 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein MSP1_C PF07462.6 CDJ63850.1 - 1.6 7.0 3.3 2.6 6.3 2.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF755 PF05501.6 CDJ63850.1 - 3.9 7.5 22.0 6.1 6.9 15.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 CDJ63850.1 - 4.2 6.7 23.5 6.7 6.1 16.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.3 CDJ63851.1 - 0.015 14.6 0.6 0.034 13.5 0.4 1.5 1 0 0 1 1 1 0 Spt20 family Macoilin PF09726.4 CDJ63851.1 - 0.021 13.1 0.0 0.86 7.8 0.0 2.4 2 1 0 2 2 2 0 Transmembrane protein dUTPase PF00692.14 CDJ63852.1 - 9.2e-17 60.7 0.0 1.3e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 dUTPase EF-hand_6 PF13405.1 CDJ63853.1 - 0.00022 20.8 1.8 0.001 18.7 1.2 2.0 1 1 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 CDJ63853.1 - 0.0043 16.2 1.5 0.0095 15.1 0.8 1.8 1 1 1 2 2 2 1 EF hand EF-hand_5 PF13202.1 CDJ63853.1 - 0.0059 15.8 1.2 0.012 14.8 0.8 1.6 1 0 0 1 1 1 1 EF hand Adap_comp_sub PF00928.16 CDJ63853.1 - 0.056 12.5 0.0 0.065 12.3 0.0 1.0 1 0 0 1 1 1 0 Adaptor complexes medium subunit family EF-hand_7 PF13499.1 CDJ63853.1 - 0.2 11.8 1.3 0.31 11.1 0.9 1.6 1 1 0 1 1 1 0 EF-hand domain pair Tcp10_C PF07202.8 CDJ63854.1 - 3.6e-07 29.8 0.0 3.4e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 T-complex protein 10 C-terminus Peptidase_M20 PF01546.23 CDJ63854.1 - 0.034 13.6 0.1 0.52 9.7 0.0 3.2 3 2 0 3 3 3 0 Peptidase family M20/M25/M40 Chromo PF00385.19 CDJ63855.1 - 1.5e-13 50.1 0.1 1.4e-12 47.1 0.0 2.0 1 1 1 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RING_2 PF13639.1 CDJ63856.1 - 1.3e-14 53.7 6.0 3.6e-14 52.2 4.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CDJ63856.1 - 4.2e-08 32.7 2.9 1.1e-07 31.4 2.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDJ63856.1 - 7.7e-08 32.2 5.9 1.9e-07 30.9 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDJ63856.1 - 1.2e-07 31.3 5.5 2.9e-07 30.0 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDJ63856.1 - 2.2e-07 30.8 6.9 7.3e-07 29.1 4.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDJ63856.1 - 3.1e-07 29.9 3.9 7.3e-07 28.7 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 CDJ63856.1 - 0.041 13.3 4.3 0.12 11.8 3.0 1.8 1 1 0 1 1 1 0 P-11 zinc finger zf-Apc11 PF12861.2 CDJ63856.1 - 0.05 13.4 5.1 0.16 11.8 3.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CDJ63856.1 - 0.21 11.6 5.3 0.74 9.9 3.7 2.0 1 0 0 1 1 1 0 RING-variant domain Pex14_N PF04695.8 CDJ63857.1 - 0.0059 16.6 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Myc_target_1 PF15179.1 CDJ63857.1 - 0.062 12.8 0.5 0.062 12.8 0.3 1.6 1 1 1 2 2 2 0 Myc target protein 1 Calpain_inhib PF00748.14 CDJ63857.1 - 0.85 9.9 5.3 1.1 9.6 3.7 1.1 1 0 0 1 1 1 0 Calpain inhibitor OmpH PF03938.9 CDJ63858.1 - 0.00037 20.4 0.3 0.00037 20.4 0.2 14.5 8 5 2 10 10 10 1 Outer membrane protein (OmpH-like) SR-25 PF10500.4 CDJ63858.1 - 0.00067 19.2 16.1 0.00067 19.2 11.1 17.3 15 1 1 17 17 17 7 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ63859.1 - 0.027 13.9 14.8 0.039 13.4 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Serglycin PF04360.7 CDJ63859.1 - 0.069 12.8 2.2 0.09 12.5 1.5 1.2 1 0 0 1 1 1 0 Serglycin FixG_C PF11614.3 CDJ63859.1 - 0.092 12.8 2.3 0.13 12.3 1.6 1.1 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase 3A PF00803.13 CDJ63859.1 - 0.34 9.9 7.5 0.39 9.7 5.2 1.1 1 0 0 1 1 1 0 3A/RNA2 movement protein family DUF1212 PF06738.7 CDJ63860.1 - 0.03 13.8 8.9 0.038 13.4 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Ycf1 PF05758.7 CDJ63860.1 - 0.088 10.5 5.0 0.076 10.7 3.5 1.1 1 0 0 1 1 1 0 Ycf1 FA_desaturase PF00487.19 CDJ63860.1 - 0.22 10.9 2.4 0.35 10.2 1.7 1.4 1 1 0 1 1 1 0 Fatty acid desaturase Glyco_transf_6 PF03414.8 CDJ63860.1 - 1 7.7 7.0 1.5 7.1 4.9 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 CmcH_NodU PF02543.10 CDJ63860.1 - 2.3 7.2 12.3 4.5 6.3 0.2 2.0 2 0 0 2 2 2 0 Carbamoyltransferase Tho2 PF11262.3 CDJ63860.1 - 2.7 6.9 14.1 4.2 6.3 9.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF247 PF03140.10 CDJ63860.1 - 6.1 5.7 10.0 4.5 6.1 6.3 1.3 1 1 0 1 1 1 0 Plant protein of unknown function Nop25 PF09805.4 CDJ63861.1 - 0.015 15.3 1.5 0.019 15.0 1.1 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2756 PF10956.3 CDJ63861.1 - 1.2 9.3 21.7 1.7 8.9 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) CDC73 PF05179.9 CDJ63861.1 - 2.1 7.6 7.6 2.6 7.3 5.3 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Lin-8 PF03353.10 CDJ63861.1 - 2.1 7.5 11.6 3 7.0 8.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.8 CDJ63861.1 - 3.4 7.1 8.1 3.5 7.0 5.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pheromone PF08015.6 CDJ63861.1 - 4.8 8.0 20.4 3.4 8.5 8.3 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone VirE2 PF07229.7 CDJ63861.1 - 5.1 5.3 9.5 7.5 4.8 6.6 1.2 1 0 0 1 1 1 0 VirE2 DUF3138 PF11336.3 CDJ63861.1 - 7.4 4.6 6.3 8.5 4.4 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Macoilin PF09726.4 CDJ63861.1 - 7.5 4.6 21.7 9.5 4.3 15.0 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2400 PF09674.5 CDJ63862.1 - 0.54 9.9 8.4 1.4 8.5 5.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) KH_1 PF00013.24 CDJ63863.1 - 1.5e-07 30.9 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 KH domain PT PF04886.7 CDJ63863.1 - 0.084 12.2 0.4 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 PT repeat EF-hand_1 PF00036.27 CDJ63866.1 - 2e-18 64.1 0.1 1.7e-05 23.7 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CDJ63866.1 - 3.2e-16 59.2 0.0 5.5e-08 32.8 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CDJ63866.1 - 1.1e-13 49.7 0.2 2.3e-05 23.5 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CDJ63866.1 - 5.6e-12 44.4 0.1 3.1e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CDJ63866.1 - 6.4e-11 41.6 2.3 0.0034 16.9 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair Dockerin_1 PF00404.13 CDJ63866.1 - 0.078 12.7 0.0 0.078 12.7 0.0 3.3 3 0 0 3 3 3 0 Dockerin type I repeat G6PD_C PF02781.11 CDJ63867.1 - 2.4e-105 351.5 0.0 2.9e-105 351.3 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Pantoate_transf PF02548.10 CDJ63868.1 - 2.1e-78 263.0 0.5 3.7e-78 262.2 0.4 1.4 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.6 CDJ63868.1 - 6.3e-12 45.5 0.3 1.7e-11 44.1 0.1 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CDJ63868.1 - 6.8e-09 35.3 0.1 4.9e-08 32.5 0.1 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PEP_mutase PF13714.1 CDJ63868.1 - 0.00083 18.6 0.3 0.0018 17.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Nol1_Nop2_Fmu PF01189.12 CDJ63870.1 - 6.9e-26 91.2 0.0 3.7e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 NOL1/NOP2/sun family cNMP_binding PF00027.24 CDJ63872.1 - 0.00047 19.9 0.1 0.1 12.4 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF2157 PF09925.4 CDJ63872.1 - 1.8 8.1 8.6 5.6 6.5 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) CRAL_TRIO PF00650.15 CDJ63873.1 - 3.7e-21 75.2 0.0 5.9e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 CDJ63873.1 - 0.067 13.4 0.5 0.86 9.8 0.0 2.3 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking Mt_ATP-synt_D PF05873.7 CDJ63874.1 - 0.016 14.8 0.1 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) OB_NTP_bind PF07717.11 CDJ63875.1 - 4.6e-17 61.8 0.0 2.5e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CDJ63875.1 - 2.6e-06 27.3 1.1 1.1e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) RED_C PF07807.6 CDJ63875.1 - 0.37 10.9 3.7 0.76 9.9 2.6 1.4 1 0 0 1 1 1 0 RED-like protein C-terminal region Tim17 PF02466.14 CDJ63876.1 - 3.5e-10 40.0 0.7 6.1e-10 39.2 0.2 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_L21p PF00829.16 CDJ63877.1 - 0.041 14.0 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein Rep_fac-A_C PF08646.5 CDJ63878.1 - 1.5e-25 89.5 0.1 3.4e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 Replication factor-A C terminal domain DZR PF12773.2 CDJ63878.1 - 0.004 16.9 1.1 0.0099 15.6 0.8 1.6 1 0 0 1 1 1 1 Double zinc ribbon tRNA_anti-codon PF01336.20 CDJ63878.1 - 0.0087 15.8 0.1 17 5.3 0.0 3.4 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DNAPolymera_Pol PF11590.3 CDJ63878.1 - 0.093 12.4 0.2 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol CSD PF00313.17 CDJ63880.1 - 0.14 11.9 0.2 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain TIP49 PF06068.8 CDJ63881.1 - 2.5e-178 592.8 0.1 3e-178 592.6 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CDJ63881.1 - 1.5e-12 47.8 0.1 1.8e-08 34.6 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDJ63881.1 - 2.7e-10 39.7 2.6 7.2e-07 28.4 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CDJ63881.1 - 1e-07 32.1 0.0 0.0041 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CDJ63881.1 - 3.8e-07 30.3 0.0 0.018 15.1 0.0 2.9 2 1 0 3 3 2 2 AAA domain AAA_5 PF07728.9 CDJ63881.1 - 3.3e-05 23.6 0.0 0.0053 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CDJ63881.1 - 3.9e-05 23.3 0.1 0.00017 21.2 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 CDJ63881.1 - 4.6e-05 24.2 0.1 0.00026 21.7 0.0 2.3 3 0 0 3 3 1 1 AAA domain AAA_14 PF13173.1 CDJ63881.1 - 0.00022 21.1 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CDJ63881.1 - 0.00031 20.1 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDJ63881.1 - 0.00038 20.7 0.0 0.0038 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 CDJ63881.1 - 0.0004 19.8 0.1 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CDJ63881.1 - 0.00051 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CDJ63881.1 - 0.00082 18.5 0.2 0.033 13.3 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CDJ63881.1 - 0.0011 18.9 0.0 0.039 13.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 CDJ63881.1 - 0.0023 17.9 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CDJ63881.1 - 0.0024 16.9 0.0 0.0061 15.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 CDJ63881.1 - 0.0029 16.7 0.1 0.0073 15.4 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.1 CDJ63881.1 - 0.0029 17.9 0.0 0.006 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDJ63881.1 - 0.0033 17.0 0.1 0.0057 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CDJ63881.1 - 0.0066 16.1 0.2 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 NTPase ResIII PF04851.10 CDJ63881.1 - 0.0083 15.9 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaB_C PF03796.10 CDJ63881.1 - 0.012 14.4 0.1 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Parvo_NS1 PF01057.12 CDJ63881.1 - 0.017 13.9 0.1 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 CDJ63881.1 - 0.017 14.7 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 CDJ63881.1 - 0.021 14.0 0.1 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 CDJ63881.1 - 0.028 14.5 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CDJ63881.1 - 0.042 13.4 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 CDJ63881.1 - 0.046 12.6 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.9 CDJ63881.1 - 0.048 12.6 0.1 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase KaiC PF06745.8 CDJ63881.1 - 0.048 12.7 0.0 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 KaiC MinE PF03776.9 CDJ63881.1 - 0.052 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE ATP-synt_ab PF00006.20 CDJ63881.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.1 CDJ63881.1 - 0.077 13.0 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 CDJ63881.1 - 0.077 12.4 0.1 0.44 9.9 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family IPT PF01745.11 CDJ63881.1 - 0.093 11.8 0.1 0.23 10.6 0.1 1.6 1 0 0 1 1 1 0 Isopentenyl transferase GvpD PF07088.6 CDJ63881.1 - 0.1 10.9 0.0 0.22 9.7 0.0 1.5 2 0 0 2 2 2 0 GvpD gas vesicle protein Rad17 PF03215.10 CDJ63881.1 - 0.13 10.9 0.0 0.26 9.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 CDJ63883.1 - 1.4e-22 80.5 0.0 2.4e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CDJ63883.1 - 1.1e-21 76.9 21.9 1.1e-21 76.9 15.2 1.4 2 0 0 2 2 2 1 ABC-2 type transporter AAA_25 PF13481.1 CDJ63883.1 - 5e-06 26.0 1.5 0.0021 17.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 CDJ63883.1 - 4.1e-05 23.6 0.0 0.00087 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 CDJ63883.1 - 0.00044 19.3 23.0 0.00055 19.0 15.5 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.1 CDJ63883.1 - 0.00088 19.6 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDJ63883.1 - 0.0026 18.5 0.0 0.0051 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDJ63883.1 - 0.005 16.8 0.8 0.016 15.2 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CDJ63883.1 - 0.0053 15.9 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DAP10 PF07213.6 CDJ63883.1 - 0.014 15.1 0.5 2.8 7.7 0.0 3.2 2 0 0 2 2 2 0 DAP10 membrane protein AAA_22 PF13401.1 CDJ63883.1 - 0.022 14.8 0.1 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CDJ63883.1 - 0.033 14.5 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CDJ63883.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CDJ63883.1 - 0.072 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_35 PF14516.1 CDJ63883.1 - 0.075 11.6 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 CDJ63883.1 - 0.078 12.4 0.1 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CDJ63883.1 - 0.082 12.3 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 CDJ63883.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 CDJ63883.1 - 0.084 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 CDJ63883.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDJ63883.1 - 0.091 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CDJ63883.1 - 0.099 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 CDJ63883.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.3 3 0 0 3 3 2 0 Part of AAA domain AAA_29 PF13555.1 CDJ63883.1 - 0.19 11.2 0.5 0.48 9.9 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_C PF00271.26 CDJ63884.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDJ63884.1 - 0.05 13.0 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF974 PF06159.8 CDJ63885.1 - 1.4e-29 103.2 0.4 1.3e-23 83.7 0.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF974) Gryzun PF07919.7 CDJ63885.1 - 8.6e-06 24.3 4.5 1.6e-05 23.4 0.2 2.3 2 1 0 2 2 2 2 Gryzun, putative trafficking through Golgi Trs65 PF12735.2 CDJ63885.1 - 0.0063 15.8 1.7 0.02 14.1 0.0 2.3 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 Transglut_C PF00927.17 CDJ63885.1 - 0.14 12.1 2.0 14 5.8 0.0 3.0 3 0 0 3 3 3 0 Transglutaminase family, C-terminal ig like domain Peptidase_M16 PF00675.15 CDJ63886.1 - 5.1e-43 146.3 0.5 2.4e-42 144.1 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CDJ63886.1 - 3.3e-20 72.5 0.2 8.4e-08 32.0 0.0 3.7 3 0 0 3 3 3 3 Peptidase M16 inactive domain Curlin_rpt PF07012.7 CDJ63886.1 - 0.0074 15.9 0.2 3.2 7.5 0.0 2.7 2 0 0 2 2 2 2 Curlin associated repeat Asp PF00026.18 CDJ63887.1 - 1.6e-26 93.2 0.0 1.2e-14 54.3 0.0 4.0 2 1 1 3 3 3 3 Eukaryotic aspartyl protease TMEM247 PF15444.1 CDJ63888.1 - 4.6 7.0 5.9 15 5.3 4.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 Amidohydro_2 PF04909.9 CDJ63889.1 - 3.8e-11 43.0 0.1 1.2e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CDJ63889.1 - 0.00081 19.4 0.0 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 CDJ63889.1 - 0.11 12.1 0.3 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Amidohydrolase family V-SNARE_C PF12352.3 CDJ63890.1 - 1.1e-07 31.7 2.2 1.1e-07 31.7 1.5 2.1 3 0 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.16 CDJ63890.1 - 0.003 17.1 1.1 0.0066 16.0 0.2 2.0 2 0 0 2 2 2 1 Synaptobrevin PEP-utilisers_N PF05524.8 CDJ63890.1 - 0.0038 16.9 0.8 0.0038 16.9 0.6 2.8 2 1 0 2 2 2 1 PEP-utilising enzyme, N-terminal Sec20 PF03908.8 CDJ63890.1 - 0.017 14.8 0.4 0.017 14.8 0.3 2.3 2 1 0 3 3 3 0 Sec20 SHNi-TPR PF10516.4 CDJ63890.1 - 0.036 13.3 0.1 0.089 12.0 0.1 1.7 1 0 0 1 1 1 0 SHNi-TPR DUF3016 PF11454.3 CDJ63890.1 - 0.1 12.1 1.9 0.16 11.5 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3016) TPR_1 PF00515.23 CDJ63890.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Acyl-CoA_dh_C PF12806.2 CDJ63890.1 - 0.14 12.0 2.4 4.2 7.2 0.2 2.6 2 1 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like ORF6C PF10552.4 CDJ63890.1 - 0.55 9.9 4.4 3.1 7.5 0.2 2.9 3 0 0 3 3 3 0 ORF6C domain Laminin_II PF06009.7 CDJ63890.1 - 0.79 9.4 8.4 2 8.1 0.5 2.7 2 2 0 2 2 2 0 Laminin Domain II DUF3664 PF12406.3 CDJ63890.1 - 0.98 10.0 7.3 0.29 11.7 2.3 2.1 1 1 1 2 2 1 0 Surface protein NPV_P10 PF05531.7 CDJ63890.1 - 2.5 8.3 6.8 34 4.7 0.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_9 PF13371.1 CDJ63890.1 - 5.4 6.9 7.8 0.24 11.2 0.5 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L28 PF00830.14 CDJ63892.1 - 1.4e-08 34.4 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L28 family DUF2053 PF09767.4 CDJ63893.1 - 2.6e-21 76.2 2.9 3.5e-21 75.8 2.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) Peptidase_C28 PF05408.6 CDJ63895.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase SET PF00856.23 CDJ63896.1 - 1.5 9.1 0.0 1.5 9.1 0.0 4.8 4 2 0 4 4 4 0 SET domain Pribosyltran PF00156.22 CDJ63898.1 - 0.11 12.1 0.2 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase domain MR_MLE_C PF13378.1 CDJ63898.1 - 0.15 12.0 2.1 0.17 11.8 1.5 1.1 1 0 0 1 1 1 0 Enolase C-terminal domain-like Claudin_2 PF13903.1 CDJ63898.1 - 0.31 10.6 1.9 0.36 10.4 1.3 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF959 PF06121.9 CDJ63898.1 - 0.34 10.5 6.1 0.38 10.3 4.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) UPF0164 PF03687.8 CDJ63898.1 - 0.6 8.5 3.8 0.63 8.5 2.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) RAB3GAP2_N PF14655.1 CDJ63898.1 - 0.69 8.8 4.1 0.7 8.8 2.8 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus R_equi_Vir PF05526.6 CDJ63898.1 - 0.69 9.5 6.1 0.73 9.4 4.3 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RskA PF10099.4 CDJ63898.1 - 0.73 9.5 13.4 0.89 9.2 9.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2946 PF11162.3 CDJ63898.1 - 0.73 10.0 9.6 0.85 9.8 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Shadoo PF14999.1 CDJ63898.1 - 0.87 9.4 6.2 1.1 9.1 4.3 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF2782 PF11191.3 CDJ63898.1 - 0.91 9.5 5.7 1 9.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Wzz PF02706.10 CDJ63898.1 - 1.1 9.0 3.4 1.3 8.7 2.3 1.1 1 0 0 1 1 1 0 Chain length determinant protein DUF3450 PF11932.3 CDJ63898.1 - 1.9 7.7 10.6 2.1 7.5 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Med15 PF09606.5 CDJ63898.1 - 2 6.5 17.6 2 6.5 12.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PsbQ PF05757.6 CDJ63898.1 - 2.5 7.4 6.6 2.7 7.3 4.6 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF2681 PF10883.3 CDJ63898.1 - 2.7 8.2 8.5 3.4 7.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Stm1_N PF09598.5 CDJ63898.1 - 4.1 8.1 10.8 2.9 8.6 6.6 1.6 1 1 0 1 1 1 0 Stm1 FAP PF07174.6 CDJ63898.1 - 6.1 6.0 12.9 6.7 5.9 8.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CDK2AP PF09806.4 CDJ63898.1 - 6.7 6.9 12.3 8.1 6.6 8.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.8 CDJ63899.1 - 0.0003 19.7 20.2 0.0003 19.7 14.0 2.0 1 1 1 2 2 1 1 BAF1 / ABF1 chromatin reorganising factor DUF4647 PF15504.1 CDJ63899.1 - 0.00065 18.6 24.6 0.00074 18.4 17.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) SR-25 PF10500.4 CDJ63899.1 - 0.0087 15.5 20.6 0.011 15.1 14.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SOBP PF15279.1 CDJ63899.1 - 0.091 13.1 21.6 0.11 12.8 15.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 CDJ63899.1 - 0.15 10.2 13.9 0.18 10.0 9.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1183 PF06682.7 CDJ63899.1 - 0.22 11.0 13.4 0.33 10.4 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4045 PF13254.1 CDJ63899.1 - 0.25 10.5 18.2 0.28 10.4 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDJ63899.1 - 0.52 9.3 17.6 0.59 9.2 12.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mitofilin PF09731.4 CDJ63899.1 - 0.6 8.7 20.1 0.64 8.5 13.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Med15 PF09606.5 CDJ63899.1 - 1 7.4 59.9 1.1 7.3 41.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TMEM51 PF15345.1 CDJ63899.1 - 1.2 8.7 23.7 1.6 8.3 16.4 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 NST1 PF13945.1 CDJ63899.1 - 1.3 9.1 28.0 1.5 8.8 19.4 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF4603 PF15376.1 CDJ63899.1 - 1.6 5.8 13.7 1.9 5.5 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SPX PF03105.14 CDJ63899.1 - 2.7 7.7 21.2 3.2 7.4 14.7 1.1 1 0 0 1 1 1 0 SPX domain Neur_chan_memb PF02932.11 CDJ63899.1 - 2.9 7.7 17.3 3.7 7.3 12.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 CDJ63899.1 - 2.9 6.7 22.6 4.7 6.0 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4648 PF15505.1 CDJ63899.1 - 2.9 8.0 9.2 4.1 7.5 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) DUF2489 PF10675.4 CDJ63899.1 - 3.4 7.3 35.5 0.092 12.4 7.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF1675 PF07897.6 CDJ63899.1 - 3.5 7.3 17.2 4.2 7.1 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Asp-B-Hydro_N PF05279.6 CDJ63899.1 - 4.2 7.1 14.7 5.3 6.8 10.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2201_N PF13203.1 CDJ63899.1 - 6.5 5.8 24.1 8.2 5.4 16.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain PAT1 PF09770.4 CDJ63899.1 - 8.4 4.4 51.7 10 4.2 35.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EOS1 PF12326.3 CDJ63899.1 - 9.1 5.9 6.1 4.6 6.8 0.1 2.1 2 0 0 2 2 2 0 N-glycosylation protein SAGA-Tad1 PF12767.2 CDJ63899.1 - 9.6 5.7 27.9 12 5.4 19.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.27 CDJ63900.1 - 2.5e-08 33.4 0.3 9.5e-08 31.6 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4281 PF14108.1 CDJ63901.1 - 0.14 12.2 0.2 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) HpaP PF09483.5 CDJ63903.1 - 4.6 7.1 26.3 5.9 6.7 1.0 2.3 2 0 0 2 2 2 0 Type III secretion protein (HpaP) AAA_33 PF13671.1 CDJ63904.1 - 0.096 12.5 4.3 0.13 12.1 0.4 2.1 1 1 1 2 2 2 0 AAA domain Draxin PF15550.1 CDJ63905.1 - 0.1 12.2 13.4 0.12 12.0 9.3 1.3 1 0 0 1 1 1 0 Draxin Macoilin PF09726.4 CDJ63905.1 - 0.2 9.9 17.0 0.29 9.3 11.8 1.3 1 0 0 1 1 1 0 Transmembrane protein YjgP_YjgQ PF03739.9 CDJ63905.1 - 0.21 10.2 3.7 0.24 10.1 2.6 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Neur_chan_memb PF02932.11 CDJ63905.1 - 0.32 10.8 9.0 0.36 10.6 6.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4342 PF14242.1 CDJ63905.1 - 0.45 10.3 2.2 1.1 9.1 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Otopetrin PF03189.8 CDJ63905.1 - 0.51 9.2 4.2 0.55 9.1 2.9 1.1 1 0 0 1 1 1 0 Otopetrin Peptidase_U57 PF05582.7 CDJ63905.1 - 0.85 8.5 9.8 1.1 8.1 6.8 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_S49_N PF08496.5 CDJ63905.1 - 1.1 9.0 16.2 2.3 7.9 11.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2217 PF10265.4 CDJ63905.1 - 1.1 7.8 16.5 1.3 7.6 11.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) LMBR1 PF04791.11 CDJ63905.1 - 1.5 7.2 4.6 1.8 7.0 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Dehydrin PF00257.14 CDJ63905.1 - 1.6 9.0 24.2 1.9 8.8 16.8 1.4 1 1 0 1 1 1 0 Dehydrin NARP1 PF12569.3 CDJ63905.1 - 1.6 7.3 16.9 2.1 6.9 11.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF3_subunit PF08597.5 CDJ63905.1 - 3.8 6.9 23.8 1.8 8.0 14.0 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Cellulose_synt PF03552.9 CDJ63905.1 - 6.2 4.9 6.0 6.4 4.9 4.2 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3915 PF13054.1 CDJ63905.1 - 8.8 6.3 6.1 5.9 6.8 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) Ndc1_Nup PF09531.5 CDJ63905.1 - 9.1 4.5 16.7 9.8 4.4 11.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.4 CDJ63906.1 - 0.0014 18.1 10.3 0.0014 18.1 7.2 5.8 2 1 4 6 6 6 1 Nuclear RNA-splicing-associated protein DUF4228 PF14009.1 CDJ63906.1 - 0.018 15.1 2.7 0.018 15.1 1.9 4.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4228) Secretin_N_2 PF07655.8 CDJ63906.1 - 0.026 14.8 3.3 0.026 14.8 2.3 5.1 2 1 1 4 4 4 0 Secretin N-terminal domain RPA_interact_M PF14767.1 CDJ63906.1 - 0.076 13.7 5.0 7.2 7.4 0.1 3.1 2 1 0 2 2 2 0 Replication protein A interacting middle HXXSHH PF07586.6 CDJ63907.1 - 0.024 13.5 8.1 0.033 13.1 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Spc24 PF08286.6 CDJ63907.1 - 0.053 13.2 5.7 0.078 12.6 4.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 APG6 PF04111.7 CDJ63907.1 - 0.078 12.0 8.9 0.094 11.7 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 CDJ63907.1 - 0.13 12.6 11.9 0.16 12.3 8.3 1.1 1 0 0 1 1 1 0 AAA domain DUF3573 PF12097.3 CDJ63907.1 - 0.19 10.3 5.6 0.22 10.1 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Suf PF05843.9 CDJ63907.1 - 0.22 11.2 10.4 0.25 11.0 7.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ63907.1 - 0.46 8.6 25.1 0.5 8.5 17.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DFF40 PF09230.5 CDJ63907.1 - 0.57 9.5 5.2 0.7 9.2 3.6 1.1 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Bud13 PF09736.4 CDJ63907.1 - 0.81 9.9 11.6 1.2 9.3 8.0 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FAD-SLDH PF12318.3 CDJ63907.1 - 1.3 8.7 15.3 2.5 7.7 10.6 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Band_3_cyto PF07565.8 CDJ63907.1 - 1.3 8.4 8.4 1.8 7.9 5.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Herpes_DNAp_acc PF04929.7 CDJ63907.1 - 1.4 7.8 7.1 1.9 7.3 4.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF1645 PF07816.6 CDJ63907.1 - 1.4 9.3 18.8 3.1 8.2 13.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) DUF3373 PF11853.3 CDJ63907.1 - 1.4 7.3 9.2 2 6.8 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF2215 PF10225.4 CDJ63907.1 - 1.5 8.2 5.0 1.8 7.9 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Serinc PF03348.10 CDJ63907.1 - 1.9 7.1 4.3 1.8 7.1 3.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.8 CDJ63907.1 - 2 8.2 24.2 2.8 7.7 16.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF106 PF01956.11 CDJ63907.1 - 2.8 7.4 7.7 3.8 7.0 5.3 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Hid1 PF12722.2 CDJ63907.1 - 3 5.4 10.7 3.6 5.1 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3138 PF11336.3 CDJ63907.1 - 3.8 5.5 26.8 0.78 7.8 7.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Presenilin PF01080.12 CDJ63907.1 - 4.3 6.0 5.9 5.2 5.7 4.1 1.1 1 0 0 1 1 1 0 Presenilin FliD_C PF07195.7 CDJ63907.1 - 7.3 5.8 11.8 11 5.2 8.2 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HlyD_2 PF12700.2 CDJ63907.1 - 9.6 5.2 10.9 13 4.8 7.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein CDK2AP PF09806.4 CDJ63908.1 - 0.19 11.9 12.4 0.24 11.6 8.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SelP_N PF04592.9 CDJ63908.1 - 0.31 10.4 3.0 0.38 10.0 2.1 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4349 PF14257.1 CDJ63908.1 - 1.8 7.7 12.6 2.4 7.3 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Pex14_N PF04695.8 CDJ63908.1 - 3.1 7.8 9.8 4.4 7.3 6.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IMS PF00817.15 CDJ63909.1 - 7.1e-32 110.2 0.0 1.1e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family TIP_N PF12457.3 CDJ63909.1 - 0.014 15.4 2.8 0.023 14.7 2.0 1.2 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Pex14_N PF04695.8 CDJ63909.1 - 0.42 10.6 13.2 0.8 9.7 9.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.3 CDJ63909.1 - 0.7 8.5 28.4 0.98 8.0 19.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CDJ63909.1 - 0.82 9.3 13.0 1.1 8.8 9.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ63909.1 - 1.3 8.2 8.2 1.9 7.8 5.7 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.8 CDJ63909.1 - 1.4 8.7 15.5 2 8.2 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 CDJ63909.1 - 4.1 4.9 5.3 5.3 4.5 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0560 PF10577.4 CDJ63909.1 - 5.7 5.0 11.2 7.4 4.6 7.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4557 PF15101.1 CDJ63909.1 - 7.3 6.3 13.7 11 5.8 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Spt20 PF12090.3 CDJ63912.1 - 0.11 11.8 18.1 0.36 10.1 0.7 2.4 2 0 0 2 2 2 0 Spt20 family YABBY PF04690.8 CDJ63912.1 - 0.46 10.7 7.9 0.2 11.8 1.2 2.3 2 0 0 2 2 2 0 YABBY protein FimP PF09766.4 CDJ63912.1 - 0.6 9.1 28.8 0.18 10.8 1.4 2.2 2 0 0 2 2 2 0 Fms-interacting protein U1snRNP70_N PF12220.3 CDJ63912.1 - 0.88 9.9 19.7 0.53 10.6 5.7 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2072 PF09845.4 CDJ63912.1 - 1.2 9.1 4.4 5.4 6.9 1.1 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DUF3408 PF11888.3 CDJ63912.1 - 4.5 7.1 14.1 8.8 6.2 4.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) SeqA PF03925.8 CDJ63912.1 - 4.7 6.8 12.7 9.2 5.9 5.0 2.3 2 0 0 2 2 2 0 SeqA protein AAA_23 PF13476.1 CDJ63912.1 - 7.4 6.8 15.9 6.1 7.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF912 PF06024.7 CDJ63912.1 - 9.1 6.4 10.8 1.2 9.1 1.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 CDJ63913.1 - 5e-07 29.3 0.0 1.3e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat GET2 PF08690.5 CDJ63913.1 - 2 7.5 7.6 3.7 6.6 5.3 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Peptidase_S64 PF08192.6 CDJ63913.1 - 8.5 4.5 10.6 12 4.0 7.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.8 CDJ63914.1 - 1.2 8.9 42.8 1.6 8.5 29.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAM-associated PF14303.1 CDJ63914.1 - 4 7.7 24.9 0.21 11.8 9.9 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain GHMP_kinases_N PF00288.21 CDJ63914.1 - 8.6 6.5 11.9 38 4.4 1.0 3.2 3 0 0 3 3 3 0 GHMP kinases N terminal domain Spt20 PF12090.3 CDJ63915.1 - 0.037 13.3 11.4 0.34 10.2 0.3 3.2 3 0 0 3 3 3 0 Spt20 family Ribosomal_S9 PF00380.14 CDJ63916.1 - 1.8e-22 79.8 0.2 2.3e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.13 CDJ63917.1 - 4.9e-61 205.3 8.2 4.9e-61 205.3 5.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L13e DUF2730 PF10805.3 CDJ63917.1 - 0.092 12.4 16.0 1.5 8.5 0.5 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Nsp1_C PF05064.8 CDJ63917.1 - 0.15 11.6 4.9 0.3 10.7 2.4 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF3373 PF11853.3 CDJ63917.1 - 0.35 9.3 1.9 0.87 8.0 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) COG7 PF10191.4 CDJ63917.1 - 3.2 5.5 9.6 0.077 10.9 1.4 1.9 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) zf-CCCH PF00642.19 CDJ63918.1 - 0.00012 21.6 20.8 0.031 13.9 0.7 3.9 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CRAL_TRIO PF00650.15 CDJ63922.1 - 1.6e-31 108.9 0.0 2.5e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CDJ63922.1 - 3.1e-06 27.1 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CDJ63922.1 - 0.0093 16.0 0.1 0.069 13.2 0.0 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.26 CDJ63923.1 - 5e-21 74.2 0.2 5e-21 74.2 0.2 2.7 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.26 CDJ63923.1 - 9.9e-17 60.7 0.3 3.7e-08 33.2 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain SAP PF02037.22 CDJ63924.1 - 3e-06 26.5 0.0 7.3e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain FtsL PF04999.8 CDJ63924.1 - 0.14 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Cell division protein FtsL zinc_ribbon_6 PF14599.1 CDJ63925.1 - 3.2e-21 74.8 1.3 3.2e-21 74.8 0.9 3.8 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 CDJ63925.1 - 2.8e-15 56.2 20.3 2.8e-15 56.2 14.1 4.3 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 CDJ63925.1 - 1.3e-07 31.3 5.3 1.3e-07 31.3 3.7 5.1 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDJ63925.1 - 1.4e-06 28.2 4.6 1.4e-06 28.2 3.2 5.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDJ63925.1 - 8.1e-06 25.4 3.4 8.1e-06 25.4 2.4 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CDJ63925.1 - 3.2e-05 23.5 4.1 3.2e-05 23.5 2.8 5.6 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ63925.1 - 5.4e-05 22.8 7.8 5.4e-05 22.8 5.4 6.0 4 2 2 6 6 6 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CDJ63925.1 - 0.0084 15.9 4.6 0.0084 15.9 3.2 5.3 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING PA PF02225.17 CDJ63926.1 - 6.6e-08 32.1 0.1 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 PA domain HMG_box_2 PF09011.5 CDJ63928.1 - 2.1e-09 37.6 0.9 9.3e-05 22.7 0.1 2.8 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 CDJ63928.1 - 3.7e-07 30.3 0.1 0.00041 20.5 0.0 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box Myb_DNA-binding PF00249.26 CDJ63928.1 - 0.0014 18.6 0.1 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain YkyA PF10368.4 CDJ63930.1 - 0.092 12.0 1.6 0.19 11.0 1.1 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Flg_hook PF02120.11 CDJ63930.1 - 0.93 9.2 5.3 2.3 7.9 0.3 3.5 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK RabGAP-TBC PF00566.13 CDJ63931.1 - 1.1e-44 152.5 0.0 1.9e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF972 PF06156.8 CDJ63931.1 - 0.061 13.6 0.8 0.16 12.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Wbp11 PF09429.5 CDJ63933.1 - 1.7e-14 53.5 7.0 2.1e-14 53.2 4.8 1.1 1 0 0 1 1 1 1 WW domain binding protein 11 Herpes_UL25 PF01499.11 CDJ63933.1 - 0.087 11.1 0.8 0.092 11.0 0.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Med19 PF10278.4 CDJ63933.1 - 0.14 11.8 3.3 0.17 11.5 2.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 COX16 PF14138.1 CDJ63933.1 - 0.33 11.1 2.1 0.47 10.6 1.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 MSC PF09402.5 CDJ63934.1 - 0.072 11.8 0.5 0.13 10.8 0.4 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PAT1 PF09770.4 CDJ63934.1 - 1.7 6.7 34.6 2.4 6.2 24.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endonuc-BsobI PF09194.5 CDJ63935.1 - 0.058 12.3 0.6 0.067 12.1 0.4 1.0 1 0 0 1 1 1 0 Restriction endonuclease BsobI Aminotran_3 PF00202.16 CDJ63935.1 - 0.086 11.6 0.1 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III Dynein_light PF01221.13 CDJ63936.1 - 5.4e-07 29.5 0.1 6.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3953 PF13129.1 CDJ63937.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) Calc_CGRP_IAPP PF00214.14 CDJ63937.1 - 1.7 8.6 15.2 2.4 8.1 10.5 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Herpes_UL87 PF03043.9 CDJ63937.1 - 2.1 6.6 10.0 2.3 6.5 6.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family YfhO PF09586.5 CDJ63937.1 - 5.2 4.9 8.0 5.7 4.8 5.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO OPA3 PF07047.7 CDJ63937.1 - 6.1 6.6 15.0 0.32 10.7 6.2 1.8 1 1 1 2 2 2 0 Optic atrophy 3 protein (OPA3) Serinc PF03348.10 CDJ63937.1 - 8.4 4.9 13.5 9.7 4.7 9.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SR-25 PF10500.4 CDJ63938.1 - 0.00035 20.0 50.5 0.04 13.3 10.1 3.4 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein SpoIIE PF07228.7 CDJ63938.1 - 0.00039 20.1 8.3 0.0016 18.1 2.1 2.9 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) AAA_23 PF13476.1 CDJ63938.1 - 0.58 10.4 13.6 0.88 9.8 9.4 1.2 1 0 0 1 1 1 0 AAA domain SAPS PF04499.10 CDJ63938.1 - 1.3 7.6 10.3 0.31 9.6 1.9 2.6 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein FemAB PF02388.11 CDJ63938.1 - 3 6.4 14.8 5.6 5.5 10.3 1.4 1 0 0 1 1 1 0 FemAB family 5_nucleotid PF05761.9 CDJ63938.1 - 6.2 5.2 8.9 9.4 4.6 6.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family Cwf_Cwc_15 PF04889.7 CDJ63938.1 - 8.7 5.9 19.0 4 7.0 5.7 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein SAGA-Tad1 PF12767.2 CDJ63939.1 - 0.043 13.4 17.1 0.09 12.4 8.6 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit zf-DHHC PF01529.15 CDJ63939.1 - 0.21 10.9 4.0 2.7 7.3 3.7 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Ycf1 PF05758.7 CDJ63939.1 - 1.2 6.8 14.1 2 6.0 9.7 1.2 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDJ63939.1 - 2 6.9 22.6 0.2 10.2 12.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ctr PF04145.10 CDJ63939.1 - 2.1 8.4 10.2 8.5 6.4 5.1 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Plasmodium_Vir PF05795.6 CDJ63939.1 - 2.7 7.1 3.7 4.3 6.4 2.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDHD PF02862.12 CDJ63939.1 - 3.9 7.1 15.6 2.2 8.0 8.8 1.9 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.1 CDJ63939.1 - 4.6 7.4 16.5 8.3 6.5 9.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FLO_LFY PF01698.11 CDJ63939.1 - 7.6 5.2 18.9 0.077 11.8 7.7 1.5 2 0 0 2 2 2 0 Floricaula / Leafy protein Herpes_DNAp_acc PF04929.7 CDJ63939.1 - 8.6 5.2 14.0 15 4.3 9.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Paramyxo_ncap PF00973.14 CDJ63939.1 - 9.6 4.7 11.7 17 3.9 8.1 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Cytomega_UL20A PF05984.7 CDJ63940.1 - 0.038 14.1 2.4 0.053 13.7 1.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Peptidase_S15 PF02129.13 CDJ63940.1 - 0.19 11.1 8.2 0.22 10.8 5.7 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FimP PF09766.4 CDJ63940.1 - 0.25 10.3 16.3 0.26 10.3 11.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDJ63940.1 - 0.31 10.3 8.7 0.36 10.1 6.1 1.3 1 0 0 1 1 1 0 Spt20 family CAF-1_p150 PF11600.3 CDJ63940.1 - 0.37 10.1 19.2 0.41 9.9 13.3 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cyto_heme_lyase PF01265.12 CDJ63940.1 - 0.75 9.3 12.2 0.8 9.2 8.5 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF4207 PF13904.1 CDJ63940.1 - 0.79 9.0 24.6 0.8 9.0 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) zf-DHHC PF01529.15 CDJ63940.1 - 1.1 8.5 3.3 1.1 8.6 2.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase PMSI1 PF15322.1 CDJ63940.1 - 1.3 8.0 9.4 1.4 7.8 6.5 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Med15 PF09606.5 CDJ63940.1 - 1.4 7.0 33.4 1.5 6.9 23.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4355 PF14265.1 CDJ63940.1 - 1.4 8.8 17.6 1.7 8.6 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) AAA_23 PF13476.1 CDJ63940.1 - 1.8 8.8 9.3 1.8 8.8 6.4 1.1 1 0 0 1 1 1 0 AAA domain DUF4175 PF13779.1 CDJ63940.1 - 2.8 5.5 25.5 2.6 5.6 17.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDJ63940.1 - 2.8 6.0 29.5 3.2 5.8 20.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.10 CDJ63940.1 - 4.3 5.9 9.2 4.2 5.9 6.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF853 PF05872.7 CDJ63940.1 - 5 5.3 10.3 5.1 5.3 7.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FLO_LFY PF01698.11 CDJ63940.1 - 5.5 5.7 14.0 5.6 5.7 9.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein R_equi_Vir PF05526.6 CDJ63940.1 - 6.8 6.2 7.4 7.5 6.1 5.1 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein OATP PF03137.15 CDJ63940.1 - 8.4 4.3 6.1 8.5 4.3 4.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PP2C_2 PF13672.1 CDJ63940.1 - 8.7 5.6 11.6 10 5.4 8.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C Borrelia_P83 PF05262.6 CDJ63942.1 - 0.00092 17.5 5.7 0.00092 17.5 3.9 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein DUF908 PF06012.7 CDJ63942.1 - 0.0093 15.2 2.6 0.012 14.9 1.8 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF4557 PF15101.1 CDJ63942.1 - 0.011 15.6 17.5 0.015 15.1 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) LON PF02190.11 CDJ63942.1 - 0.014 15.1 2.2 0.019 14.6 1.5 1.4 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF2347 PF09804.4 CDJ63942.1 - 0.023 14.0 6.4 0.031 13.5 4.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF342 PF03961.8 CDJ63942.1 - 0.056 11.8 10.9 0.067 11.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cyclin_C PF02984.14 CDJ63942.1 - 0.065 13.1 6.9 0.096 12.6 4.8 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain Mago-bind PF09282.5 CDJ63942.1 - 0.08 12.5 0.1 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Mago binding FAD-SLDH PF12318.3 CDJ63942.1 - 0.11 12.1 11.4 0.15 11.6 7.9 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Suf PF05843.9 CDJ63942.1 - 0.13 11.9 14.4 0.19 11.4 10.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ63942.1 - 0.18 10.0 32.1 0.21 9.7 22.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ63942.1 - 0.4 10.9 21.5 0.6 10.3 14.9 1.3 1 0 0 1 1 1 0 AAA domain DDHD PF02862.12 CDJ63942.1 - 0.58 9.9 8.4 0.76 9.5 5.8 1.1 1 0 0 1 1 1 0 DDHD domain ORC5_C PF14630.1 CDJ63942.1 - 0.61 9.5 9.9 0.81 9.0 6.9 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Peptidase_U57 PF05582.7 CDJ63942.1 - 0.8 8.6 9.4 1 8.2 6.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 EIIBC-GUT_N PF03612.9 CDJ63942.1 - 0.88 9.1 5.5 1.3 8.6 3.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus V_ATPase_I PF01496.14 CDJ63942.1 - 0.94 7.2 9.4 1.1 7.0 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ABC2_membrane_3 PF12698.2 CDJ63942.1 - 1 8.2 5.5 1.4 7.8 3.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein OmpH PF03938.9 CDJ63942.1 - 1.2 9.0 44.8 1.9 8.4 31.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0565 PF10561.4 CDJ63942.1 - 2.1 7.1 9.8 2.9 6.6 6.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 FAM60A PF15396.1 CDJ63942.1 - 2.1 8.0 7.6 2.8 7.6 5.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Exonuc_VII_L PF02601.10 CDJ63942.1 - 2.3 7.3 18.3 3 6.9 12.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Folliculin PF11704.3 CDJ63942.1 - 2.4 7.7 10.4 3.8 7.0 7.2 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SprA-related PF12118.3 CDJ63942.1 - 2.4 7.3 35.9 3 7.0 24.9 1.1 1 0 0 1 1 1 0 SprA-related family Band_3_cyto PF07565.8 CDJ63942.1 - 2.7 7.4 14.2 4.1 6.8 9.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.1 CDJ63942.1 - 3.1 6.6 18.2 4.3 6.2 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 CDJ63942.1 - 3.5 8.0 18.7 6.8 7.0 13.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1266 PF06889.6 CDJ63942.1 - 4.5 7.0 14.4 9.5 5.9 10.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) APG6 PF04111.7 CDJ63942.1 - 4.7 6.1 24.9 6.7 5.6 17.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HI0933_like PF03486.9 CDJ63942.1 - 5.3 5.4 14.5 7.3 4.9 10.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Het-C PF07217.6 CDJ63942.1 - 7.9 4.5 10.4 10 4.1 7.2 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF2927 PF11150.3 CDJ63943.1 - 0.033 13.8 5.0 0.035 13.7 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) Pex14_N PF04695.8 CDJ63943.1 - 0.041 13.9 4.0 0.048 13.7 2.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3138 PF11336.3 CDJ63943.1 - 0.073 11.2 20.6 0.087 10.9 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) OmpH PF03938.9 CDJ63943.1 - 0.085 12.7 19.7 0.12 12.2 13.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4139 PF13598.1 CDJ63943.1 - 0.15 11.3 9.7 0.15 11.2 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) WES_acyltransf PF03007.11 CDJ63943.1 - 0.34 10.4 5.8 0.38 10.2 4.0 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Med15 PF09606.5 CDJ63943.1 - 0.35 9.0 20.5 0.41 8.7 14.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SpaB_C PF14028.1 CDJ63943.1 - 0.38 10.2 13.0 0.43 10.0 9.0 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain PIG-S PF10510.4 CDJ63943.1 - 0.38 9.3 3.5 0.4 9.2 2.5 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein PIH1 PF08190.7 CDJ63943.1 - 0.72 9.2 5.2 0.73 9.2 3.6 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF2360 PF10152.4 CDJ63943.1 - 0.73 10.1 8.2 0.97 9.7 5.7 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MSP1_C PF07462.6 CDJ63943.1 - 1 7.6 7.0 1.1 7.5 4.8 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Rifin_STEVOR PF02009.11 CDJ63943.1 - 1.3 8.6 5.5 1.4 8.4 3.8 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF2486 PF10667.4 CDJ63943.1 - 2.7 8.4 18.5 3.1 8.2 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Asp-B-Hydro_N PF05279.6 CDJ63943.1 - 2.8 7.7 6.7 3.1 7.5 4.7 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Kei1 PF08552.6 CDJ63943.1 - 3.3 7.3 6.7 3.6 7.1 4.7 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Spore_YhcN_YlaJ PF09580.5 CDJ63943.1 - 3.4 7.7 6.6 4 7.5 4.6 1.0 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1501 PF07394.7 CDJ63943.1 - 3.5 6.3 9.2 3.8 6.2 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF4557 PF15101.1 CDJ63943.1 - 4.6 7.0 11.2 5.3 6.8 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hep_59 PF07052.6 CDJ63943.1 - 5.2 7.5 8.1 7.4 6.9 5.6 1.4 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 TFIIA PF03153.8 CDJ63943.1 - 7.1 6.4 12.6 7.7 6.3 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit E_Pc_C PF06752.7 CDJ63943.1 - 7.7 5.9 19.8 8.9 5.7 13.8 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus RINGv PF12906.2 CDJ63944.1 - 4.4e-13 49.0 6.3 1e-12 47.8 4.4 1.7 1 1 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 CDJ63944.1 - 0.025 14.5 1.4 0.051 13.5 1.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain RAB3GAP2_N PF14655.1 CDJ63944.1 - 4.1 6.2 6.2 7.6 5.4 3.9 1.6 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus APC_CDC26 PF10471.4 CDJ63945.1 - 0.084 13.6 7.3 0.13 12.9 5.1 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF2859 PF11072.3 CDJ63945.1 - 0.19 11.2 4.3 0.14 11.6 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2859) TMEM51 PF15345.1 CDJ63945.1 - 0.66 9.6 5.7 0.77 9.4 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 WES_acyltransf PF03007.11 CDJ63945.1 - 2 7.8 13.5 2.5 7.5 9.3 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain PAT1 PF09770.4 CDJ63945.1 - 2.5 6.2 10.8 2.8 6.0 7.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4418 PF14387.1 CDJ63945.1 - 8.1 6.2 9.0 1.1 9.0 3.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) TCP PF03634.8 CDJ63945.1 - 9.9 6.5 12.7 13 6.2 8.8 1.1 1 0 0 1 1 1 0 TCP family transcription factor K_channel_TID PF07941.6 CDJ63946.1 - 0.0012 19.0 4.2 0.0012 19.0 2.9 12.0 7 3 2 9 9 9 1 Potassium channel Kv1.4 tandem inactivation domain FimP PF09766.4 CDJ63946.1 - 0.0012 17.9 5.9 0.0012 17.9 4.1 5.4 6 1 0 6 6 6 1 Fms-interacting protein Med15 PF09606.5 CDJ63946.1 - 0.0013 17.0 36.6 0.0013 17.0 25.4 3.6 3 1 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF912 PF06024.7 CDJ63946.1 - 0.0049 16.8 0.4 0.0049 16.8 0.3 6.2 5 1 1 6 6 6 1 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 CDJ63946.1 - 0.045 14.0 0.2 0.045 14.0 0.1 3.6 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FA_desaturase PF00487.19 CDJ63946.1 - 0.059 12.7 0.1 3.4 7.0 0.2 2.5 2 0 0 2 2 2 0 Fatty acid desaturase GPDPase_memb PF10110.4 CDJ63946.1 - 0.085 12.2 0.6 0.21 11.0 0.4 1.6 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF3899 PF13038.1 CDJ63946.1 - 0.78 9.9 4.0 2.8 8.1 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) DEAD PF00270.24 CDJ63947.1 - 1.7e-35 122.0 3.6 1.5e-34 118.9 0.0 3.3 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ63947.1 - 1.1e-21 76.4 0.0 1.1e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pox_A32 PF04665.7 CDJ63947.1 - 0.22 10.7 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 CDJ63947.1 - 0.65 10.1 0.0 0.65 10.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain RRM_6 PF14259.1 CDJ63948.1 - 4.9e-20 71.2 1.6 3.1e-06 27.0 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ63948.1 - 2.4e-18 65.5 0.8 5.9e-06 25.8 0.2 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ63948.1 - 5.4e-18 64.5 0.5 0.00014 21.5 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP2C_2 PF13672.1 CDJ63949.1 - 0.0018 17.7 6.8 0.0023 17.3 4.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C DUF2029 PF09594.5 CDJ63949.1 - 0.0021 17.5 0.4 0.0023 17.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) VIT1 PF01988.14 CDJ63949.1 - 0.025 14.0 1.6 0.027 13.9 1.1 1.1 1 0 0 1 1 1 0 VIT family Abhydrolase_9_N PF15420.1 CDJ63949.1 - 0.065 12.9 2.9 0.086 12.5 2.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2232 PF09991.4 CDJ63949.1 - 0.11 11.5 3.6 0.13 11.2 2.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF418 PF04235.7 CDJ63949.1 - 0.11 12.1 1.3 0.15 11.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) Ribosomal_60s PF00428.14 CDJ63949.1 - 0.98 9.8 12.5 1.5 9.3 8.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Gastrin PF00918.12 CDJ63949.1 - 7.1 7.4 13.6 9.2 7.1 9.4 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family BAF1_ABF1 PF04684.8 CDJ63950.1 - 0.0046 15.8 14.5 0.0046 15.8 10.1 2.2 2 0 0 2 2 2 2 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDJ63950.1 - 0.029 14.6 18.9 0.029 14.6 13.1 2.4 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.8 CDJ63950.1 - 0.17 11.7 34.7 0.21 11.4 24.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CDJ63950.1 - 0.8 9.0 30.8 1 8.7 21.3 1.1 1 0 0 1 1 1 0 Vta1 like SPX PF03105.14 CDJ63950.1 - 2.6 7.7 28.6 1.6e+03 -1.4 19.9 2.1 1 1 0 1 1 1 0 SPX domain Peptidase_S64 PF08192.6 CDJ63950.1 - 2.7 6.2 19.3 3.6 5.7 13.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 AAA_23 PF13476.1 CDJ63950.1 - 4.2 7.6 12.9 6.3 7.0 0.4 2.2 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.4 CDJ63950.1 - 8.2 4.5 29.8 12 4.0 20.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4551 PF15087.1 CDJ63950.1 - 9.4 4.4 24.1 13 3.9 16.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPX PF03105.14 CDJ63952.1 - 0.00056 19.7 0.5 0.00056 19.7 0.3 2.4 2 1 0 2 2 2 1 SPX domain Borrelia_P83 PF05262.6 CDJ63952.1 - 0.092 10.9 22.8 0.13 10.4 11.5 2.2 2 0 0 2 2 2 0 Borrelia P83/100 protein TFIIA PF03153.8 CDJ63952.1 - 1.2 8.9 35.8 1.1 9.0 8.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DNA_pol_viral_N PF00242.12 CDJ63952.1 - 4.6 6.1 20.3 0.13 11.2 9.4 1.7 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Med15 PF09606.5 CDJ63953.1 - 0.038 12.2 34.3 0.045 11.9 23.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HI0933_like PF03486.9 CDJ63953.1 - 0.83 8.0 6.3 1.3 7.4 4.3 1.4 1 0 0 1 1 1 0 HI0933-like protein DUF342 PF03961.8 CDJ63953.1 - 6 5.1 13.9 0.12 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) RAB3GAP2_N PF14655.1 CDJ63955.1 - 0.043 12.8 2.7 0.057 12.4 1.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1205 PF06722.7 CDJ63955.1 - 0.13 12.5 1.1 0.28 11.4 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1205) Glyco_hydro_3_C PF01915.17 CDJ63955.1 - 0.32 10.4 2.5 0.73 9.3 1.7 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain BAF1_ABF1 PF04684.8 CDJ63955.1 - 5.4 5.7 7.6 2.3 6.9 0.2 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor RICTOR_N PF14664.1 CDJ63956.1 - 0.3 9.6 1.9 0.38 9.2 0.6 1.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Pex14_N PF04695.8 CDJ63956.1 - 0.47 10.5 22.0 0.11 12.5 10.4 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.7 CDJ63956.1 - 2.5 6.6 12.4 3.7 6.0 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF912 PF06024.7 CDJ63956.1 - 4 7.5 7.0 7.4 6.6 4.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4557 PF15101.1 CDJ63956.1 - 8.3 6.1 25.2 3.3 7.4 14.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Nucleo_P87 PF07267.6 CDJ63956.1 - 9.6 4.7 11.1 15 4.1 7.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 EIIBC-GUT_N PF03612.9 CDJ63956.1 - 9.7 5.7 6.8 17 4.9 4.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_M14 PF00246.19 CDJ63957.1 - 5.9e-16 58.8 0.0 7.4e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase RAB3GAP2_N PF14655.1 CDJ63957.1 - 0.02 13.9 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2331 PF10093.4 CDJ63957.1 - 0.031 13.0 0.1 0.044 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) Glyco_hydro_3 PF00933.16 CDJ63957.1 - 0.07 12.1 0.1 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain DUF1162 PF06650.7 CDJ63958.1 - 1.5e-16 60.4 0.0 2.2e-15 56.6 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1162) DUF2561 PF10812.3 CDJ63960.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Peptidase_C37 PF05416.7 CDJ63960.1 - 0.13 10.5 0.0 0.14 10.4 0.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Lin0512_fam PF09585.5 CDJ63961.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) TPR_12 PF13424.1 CDJ63964.1 - 0.0017 18.2 2.0 0.21 11.5 0.0 2.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TRC8_N PF13705.1 CDJ63964.1 - 0.0091 14.6 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 TRC8 N-terminal domain Apc3 PF12895.2 CDJ63964.1 - 0.14 12.2 1.5 1.5 9.0 0.9 2.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 CDJ63964.1 - 1.8 9.1 4.6 3.9 8.1 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Gp_dh_C PF02800.15 CDJ63967.1 - 9.2e-70 233.1 0.0 1.3e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CDJ63967.1 - 9.1e-61 204.2 0.1 1.5e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CDJ63967.1 - 0.018 14.9 0.1 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF1330 PF07045.6 CDJ63967.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) RNase_H PF00075.19 CDJ63968.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 RNase H RVT_3 PF13456.1 CDJ63968.1 - 0.045 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like Cyclin PF08613.6 CDJ63969.1 - 1.8e-09 38.1 0.1 6e-08 33.2 0.0 2.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CDJ63969.1 - 0.044 13.3 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain ATP-synt_10 PF05176.9 CDJ63970.1 - 0.00035 19.9 0.0 0.73 9.0 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein Psb28 PF03912.9 CDJ63970.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Psb28 protein tRNA-synt_His PF13393.1 CDJ63971.1 - 6e-17 61.6 1.4 1.7e-08 33.8 0.0 3.5 4 0 0 4 4 4 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CDJ63971.1 - 3.3e-07 30.0 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_L7Ae PF01248.21 CDJ63972.1 - 9e-23 79.6 1.5 1.6e-22 78.7 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CDJ63972.1 - 0.024 14.4 0.1 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 Metallophos_2 PF12850.2 CDJ63973.1 - 4.4e-19 68.8 0.0 5.3e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CDJ63973.1 - 0.00027 20.3 1.7 0.00077 18.9 1.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CHCH PF06747.8 CDJ63974.1 - 6.5e-05 22.7 2.2 0.00015 21.5 1.4 1.7 1 1 1 2 2 2 2 CHCH domain VAD1-2 PF15310.1 CDJ63974.1 - 0.017 14.7 0.0 0.021 14.4 0.0 1.0 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling PAT1 PF09770.4 CDJ63975.1 - 3.4 5.8 15.3 3.8 5.6 10.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-5_eIF-2B PF01873.12 CDJ63976.1 - 9.1e-35 119.0 0.0 1.9e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CDJ63976.1 - 5.4e-13 48.6 0.1 5.4e-13 48.6 0.1 3.0 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon eIF-3c_N PF05470.7 CDJ63976.1 - 0.074 11.1 11.3 0.089 10.8 7.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SOBP PF15279.1 CDJ63976.1 - 0.27 11.6 3.8 0.39 11.0 2.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.10 CDJ63976.1 - 0.35 9.4 8.3 0.43 9.1 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 CDJ63976.1 - 0.7 7.7 21.3 0.93 7.3 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4349 PF14257.1 CDJ63976.1 - 2.6 7.2 6.0 6.7 5.8 4.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Neur_chan_memb PF02932.11 CDJ63976.1 - 7.3 6.3 6.3 11 5.8 4.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MIP-T3 PF10243.4 CDJ63976.1 - 7.5 4.9 33.2 11 4.3 23.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ribosomal_60s PF00428.14 CDJ63977.1 - 0.015 15.6 6.6 0.015 15.6 4.6 3.6 3 2 0 3 3 3 0 60s Acidic ribosomal protein DUF755 PF05501.6 CDJ63979.1 - 0.68 10.0 30.4 0.12 12.4 14.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF4642 PF15484.1 CDJ63979.1 - 1.3 9.0 9.0 0.31 10.9 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4642) SR-25 PF10500.4 CDJ63979.1 - 1.4 8.3 28.9 0.21 11.0 15.7 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.8 CDJ63979.1 - 1.5 8.6 13.3 1.7 8.4 9.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.12 CDJ63979.1 - 1.8 8.3 8.4 2.5 7.8 5.9 1.2 1 0 0 1 1 1 0 DDHD domain CAF-1_p150 PF11600.3 CDJ63979.1 - 4.2 6.6 20.0 0.089 12.1 9.4 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 CDJ63979.1 - 6.4 4.9 13.8 9.2 4.4 9.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1675 PF07897.6 CDJ63979.1 - 8.2 6.2 13.2 11 5.7 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Activator_LAG-3 PF11498.3 CDJ63980.1 - 0.00025 19.9 7.8 0.00025 19.9 5.4 6.3 7 0 0 7 7 7 2 Transcriptional activator LAG-3 Peptidase_M16_C PF05193.16 CDJ63982.1 - 0.0026 17.4 0.0 0.0026 17.4 0.0 4.3 4 1 1 5 5 5 1 Peptidase M16 inactive domain Phostensin_N PF13916.1 CDJ63982.1 - 0.003 17.5 2.3 0.003 17.5 1.6 8.3 6 2 2 8 8 8 3 PP1-regulatory protein, Phostensin N-terminal OAD_gamma PF04277.8 CDJ63982.1 - 0.28 11.6 0.0 0.28 11.6 0.0 6.2 5 2 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain LRR_4 PF12799.2 CDJ63983.1 - 5.4e-10 38.6 19.6 0.0015 18.0 1.3 4.6 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ63983.1 - 2.2e-05 24.1 17.2 0.00086 19.0 3.1 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CDJ63983.1 - 1.7 9.0 11.7 1.1 9.5 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat PBP1_TM PF14812.1 CDJ63984.1 - 0.0037 17.5 1.3 0.0037 17.5 0.9 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4557 PF15101.1 CDJ63984.1 - 0.0097 15.7 33.9 0.053 13.3 14.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4557) DUF966 PF06136.8 CDJ63984.1 - 0.029 13.8 15.3 0.043 13.2 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Gti1_Pac2 PF09729.4 CDJ63984.1 - 0.04 13.7 7.5 0.08 12.8 2.1 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family CPSF100_C PF13299.1 CDJ63984.1 - 0.052 13.7 12.1 0.072 13.2 3.9 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RED_N PF07808.8 CDJ63984.1 - 0.16 11.1 27.3 0.18 11.0 11.7 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region Band_3_cyto PF07565.8 CDJ63984.1 - 0.19 11.2 14.8 0.26 10.7 5.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SeqA PF03925.8 CDJ63984.1 - 0.19 11.4 12.4 0.079 12.6 4.0 2.2 2 0 0 2 2 2 0 SeqA protein DUF3371 PF11851.3 CDJ63984.1 - 0.22 12.2 24.8 2.1 9.0 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) TAF4 PF05236.9 CDJ63984.1 - 0.25 10.5 27.5 0.23 10.6 7.7 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family DUF2052 PF09747.4 CDJ63984.1 - 0.39 10.6 18.8 3.5 7.5 9.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF913 PF06025.7 CDJ63984.1 - 1.1 7.8 7.0 0.21 10.2 1.7 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.7 CDJ63984.1 - 1.4 8.7 19.5 0.22 11.3 6.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 CDJ63984.1 - 1.6 7.3 20.1 0.028 13.2 6.7 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 FCP1_C PF09309.5 CDJ63984.1 - 1.7 7.8 28.5 0.27 10.5 2.2 2.4 2 0 0 2 2 2 0 FCP1, C-terminal DUF3408 PF11888.3 CDJ63984.1 - 1.8 8.5 14.8 1.4 8.8 5.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Rtf2 PF04641.7 CDJ63984.1 - 1.9 7.6 16.2 0.6 9.2 5.3 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Afi1 PF07792.7 CDJ63984.1 - 2 8.4 13.8 10 6.1 6.8 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PEX11 PF05648.9 CDJ63984.1 - 2 7.5 9.1 1.6 7.9 2.7 2.1 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) FHIPEP PF00771.15 CDJ63984.1 - 2.6 6.2 12.9 0.31 9.3 3.5 2.1 2 0 0 2 2 2 0 FHIPEP family CRF1 PF10380.4 CDJ63984.1 - 3 8.2 11.2 1.9 8.8 3.4 2.3 2 0 0 2 2 2 0 Transcription factor CRF1 Folliculin PF11704.3 CDJ63984.1 - 3.4 7.2 13.0 5.6 6.5 0.3 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport FAM176 PF14851.1 CDJ63984.1 - 3.6 7.2 9.6 4 7.0 4.3 2.1 2 0 0 2 2 2 0 FAM176 family zf-DHHC PF01529.15 CDJ63984.1 - 3.7 6.9 13.0 0.44 9.9 1.6 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase MRP-S31 PF15433.1 CDJ63984.1 - 4.2 6.7 29.0 0.066 12.6 7.5 2.4 3 0 0 3 3 2 0 Mitochondrial 28S ribosomal protein S31 Peptidase_S15 PF02129.13 CDJ63984.1 - 5 6.4 22.3 0.83 9.0 9.5 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) CDC45 PF02724.9 CDJ63984.1 - 5.8 4.8 13.6 0.6 8.0 5.0 1.9 2 0 0 2 2 2 0 CDC45-like protein DHHW PF14286.1 CDJ63984.1 - 6.2 6.0 13.5 0.69 9.1 4.7 2.0 2 0 0 2 2 2 0 DHHW protein DUF853 PF05872.7 CDJ63984.1 - 7.6 4.7 19.1 2.9 6.1 7.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Agouti PF05039.7 CDJ63984.1 - 7.7 6.9 15.4 6.8 7.1 0.8 2.5 2 0 0 2 2 2 0 Agouti protein Plasmodium_Vir PF05795.6 CDJ63984.1 - 8.2 5.5 5.6 2.8 7.0 1.1 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Bul1_N PF04425.7 CDJ63984.1 - 8.4 4.8 12.8 0.57 8.6 4.4 1.9 2 0 0 2 2 2 0 Bul1 N terminus DUF912 PF06024.7 CDJ63984.1 - 9.5 6.3 13.9 1.7 8.6 3.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Dala_Dala_lig_N PF01820.16 CDJ63984.1 - 9.6 6.5 10.9 16 5.8 4.2 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus zf-MYND PF01753.13 CDJ63986.1 - 5.5e-12 45.3 6.8 2e-11 43.5 4.7 2.0 1 0 0 1 1 1 1 MYND finger SET PF00856.23 CDJ63986.1 - 2.8e-09 37.4 0.2 8.6e-08 32.6 0.1 2.5 1 1 0 1 1 1 1 SET domain Ribophorin_I PF04597.9 CDJ63987.1 - 4.4e-51 173.7 0.0 7e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Ribophorin I DUF1488 PF07369.6 CDJ63987.1 - 0.0086 15.8 2.0 0.35 10.7 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1488) DUF4618 PF15397.1 CDJ63987.1 - 0.015 14.6 0.4 0.027 13.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2422 PF10337.4 CDJ63987.1 - 0.022 13.5 2.4 0.031 13.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) zf-LSD1 PF06943.7 CDJ63987.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 LSD1 zinc finger PilJ PF13675.1 CDJ63988.1 - 0.11 12.8 2.1 0.2 12.0 1.4 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Muted PF14942.1 CDJ63988.1 - 0.15 11.9 0.7 0.32 10.8 0.4 1.6 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein SR-25 PF10500.4 CDJ63989.1 - 0.19 11.1 10.8 0.26 10.7 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Consortin_C PF15281.1 CDJ63989.1 - 0.68 9.4 3.1 0.88 9.0 0.0 2.3 2 0 0 2 2 2 0 Consortin C-terminus DUF2217 PF10265.4 CDJ63989.1 - 1 8.0 4.8 1.3 7.6 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF755 PF05501.6 CDJ63989.1 - 3.7 7.6 24.4 6.7 6.7 16.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Med15 PF09606.5 CDJ63989.1 - 4.7 5.2 27.5 6 4.9 19.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1700 PF08006.6 CDJ63989.1 - 9.1 5.5 10.5 32 3.7 5.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) SR-25 PF10500.4 CDJ63990.1 - 4.7e-05 22.9 11.2 5.4e-05 22.7 7.8 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ63990.1 - 0.042 13.2 4.1 0.046 13.0 2.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal KduI PF04962.7 CDJ63990.1 - 0.1 11.6 4.1 0.11 11.5 2.8 1.0 1 0 0 1 1 1 0 KduI/IolB family SelP_N PF04592.9 CDJ63990.1 - 0.17 11.2 3.6 0.18 11.1 2.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pex14_N PF04695.8 CDJ63990.1 - 0.97 9.4 9.0 1.2 9.1 6.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RFamide_26RFa PF11109.3 CDJ63990.1 - 1.2 9.0 6.2 1.2 8.9 3.9 1.3 1 1 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 DUF3292 PF11696.3 CDJ63990.1 - 1.5 6.6 11.7 1.7 6.3 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Dsh_C PF12316.3 CDJ63990.1 - 3.6 7.6 13.8 4.4 7.3 9.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal APC_CDC26 PF10471.4 CDJ63990.1 - 3.7 8.3 13.6 0.16 12.7 4.3 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 Med15 PF09606.5 CDJ63990.1 - 4.2 5.4 13.3 4.3 5.4 9.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4603 PF15376.1 CDJ63990.1 - 5.7 3.9 9.3 5.6 4.0 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Macoilin PF09726.4 CDJ63990.1 - 6.2 4.9 9.7 8.8 4.4 6.7 1.2 1 0 0 1 1 1 0 Transmembrane protein ETRAMP PF09716.5 CDJ63990.1 - 9.8 6.2 11.2 19 5.2 7.8 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) BNIP3 PF06553.7 CDJ63991.1 - 8 5.7 13.5 10 5.4 9.4 1.2 1 0 0 1 1 1 0 BNIP3 Suf PF05843.9 CDJ63993.1 - 0.013 15.2 11.1 0.013 15.2 7.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.3 CDJ63993.1 - 0.054 12.8 22.6 0.053 12.8 15.7 1.1 1 0 0 1 1 1 0 SprA-related family FCP1_C PF09309.5 CDJ63993.1 - 0.06 12.6 9.5 0.07 12.4 6.6 1.3 1 0 0 1 1 1 0 FCP1, C-terminal OmpH PF03938.9 CDJ63993.1 - 0.073 12.9 29.7 0.085 12.7 20.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FimP PF09766.4 CDJ63993.1 - 0.12 11.4 18.6 0.15 11.1 12.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein Peptidase_S49_N PF08496.5 CDJ63993.1 - 0.12 12.1 11.7 0.15 11.8 8.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_23 PF13476.1 CDJ63993.1 - 0.13 12.5 15.0 0.15 12.3 10.4 1.1 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDJ63993.1 - 0.23 9.6 36.1 0.23 9.6 25.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal APG6 PF04111.7 CDJ63993.1 - 0.28 10.1 16.3 0.34 9.9 11.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-DHHC PF01529.15 CDJ63993.1 - 0.39 10.1 2.3 0.4 10.0 1.6 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF912 PF06024.7 CDJ63993.1 - 0.5 10.4 5.2 0.72 9.9 3.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0564 PF10595.4 CDJ63993.1 - 0.52 9.1 22.0 0.52 9.1 15.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 RR_TM4-6 PF06459.7 CDJ63993.1 - 0.74 9.6 8.7 0.77 9.6 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3963 PF13124.1 CDJ63993.1 - 0.76 9.6 0.1 0.76 9.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3963) WHG PF13305.1 CDJ63993.1 - 1.5 9.4 3.7 16 6.1 0.0 2.6 2 1 0 2 2 2 0 WHG domain AIF_C PF14721.1 CDJ63993.1 - 2.1 8.6 7.9 3.1 8.0 5.5 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Band_3_cyto PF07565.8 CDJ63993.1 - 2.3 7.6 10.6 2.8 7.3 7.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 CDJ63993.1 - 2.4 8.1 16.8 3.6 7.6 11.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.14 CDJ63993.1 - 2.9 5.6 10.0 3.2 5.4 6.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.1 CDJ63993.1 - 4 7.1 9.2 5 6.8 6.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3299 PF11736.3 CDJ63993.1 - 4.4 7.2 13.1 6.6 6.6 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Mnd1 PF03962.10 CDJ63993.1 - 4.4 6.9 22.7 7.7 6.1 15.7 1.3 1 0 0 1 1 1 0 Mnd1 family DUF2992 PF11208.3 CDJ63993.1 - 5.3 6.9 23.7 17 5.3 16.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) KfrA_N PF11740.3 CDJ63993.1 - 5.4 7.5 31.0 5.4 7.4 0.0 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term BAF1_ABF1 PF04684.8 CDJ63993.1 - 5.5 5.7 30.5 5.9 5.6 21.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serinc PF03348.10 CDJ63993.1 - 7 5.2 9.8 7.7 5.0 6.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex14_N PF04695.8 CDJ63994.1 - 0.016 15.2 25.5 0.016 15.2 17.7 4.4 1 1 2 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2232 PF09991.4 CDJ63994.1 - 1.6 7.6 7.5 2.8 6.8 5.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF3154 PF11351.3 CDJ63995.1 - 0.0082 15.8 2.7 0.0082 15.8 1.9 5.3 4 1 2 6 6 6 1 Protein of unknown function (DUF3154) Ribosomal_60s PF00428.14 CDJ63995.1 - 0.019 15.3 11.0 0.019 15.3 7.6 6.5 4 1 2 6 6 6 0 60s Acidic ribosomal protein APC_CDC26 PF10471.4 CDJ63995.1 - 0.036 14.8 1.8 0.036 14.8 1.3 5.0 4 1 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 SAPS PF04499.10 CDJ63995.1 - 0.15 10.6 8.0 11 4.5 5.3 2.4 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 CDJ63995.1 - 2.2 8.0 18.9 3.7e+02 0.8 13.1 2.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TOMM6 PF15184.1 CDJ63996.1 - 0.06 12.6 0.5 0.16 11.3 0.4 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Kinesin PF00225.18 CDJ63998.1 - 1.6e-18 66.4 3.7 5.2e-18 64.8 0.0 2.7 2 0 0 2 2 2 1 Kinesin motor domain HSP20 PF00011.16 CDJ63999.1 - 0.019 14.7 0.0 0.019 14.7 0.0 3.1 4 0 0 4 4 4 0 Hsp20/alpha crystallin family IBP39 PF11422.3 CDJ63999.1 - 0.024 14.1 0.9 2.6 7.4 0.4 2.4 1 1 1 2 2 2 0 Initiator binding protein 39 kDa DUF3306 PF11748.3 CDJ63999.1 - 0.084 13.5 13.1 0.12 13.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) RskA PF10099.4 CDJ63999.1 - 0.09 12.5 12.6 0.23 11.1 0.2 2.7 2 1 0 2 2 2 0 Anti-sigma-K factor rskA TrbC_Ftype PF09673.5 CDJ63999.1 - 0.21 11.1 5.0 0.51 9.9 0.2 3.0 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein RAB3GAP2_N PF14655.1 CDJ63999.1 - 0.37 9.7 15.3 0.82 8.6 1.3 3.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WBP-1 PF11669.3 CDJ63999.1 - 0.92 9.6 14.0 6.8 6.8 1.1 3.3 3 0 0 3 3 3 0 WW domain-binding protein 1 PHD_3 PF13922.1 CDJ63999.1 - 2.8 8.2 23.1 7.8 6.8 0.7 3.3 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx DUF533 PF04391.7 CDJ63999.1 - 3.6 6.9 17.1 0.23 10.8 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF533) DUF4207 PF13904.1 CDJ63999.1 - 3.6 6.8 25.8 1.4 8.2 4.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) PCYCGC PF13798.1 CDJ63999.1 - 7.7 6.1 10.7 1.3 8.6 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function with PCYCGC motif FAM195 PF14799.1 CDJ63999.1 - 8 6.3 29.4 5.2 6.9 1.3 3.5 3 1 0 3 3 3 0 FAM195 family Bap31 PF05529.7 CDJ63999.1 - 8.2 5.8 10.2 6.1 6.2 2.1 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4094 PF13334.1 CDJ63999.1 - 8.5 6.8 12.3 22 5.5 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) zf-CCHC PF00098.18 CDJ64004.1 - 1.2e-05 24.9 1.6 2.6e-05 23.9 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ64004.1 - 0.0012 18.4 0.4 0.0027 17.3 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ64004.1 - 0.0016 18.0 0.7 0.0044 16.6 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CDJ64004.1 - 0.013 15.5 0.0 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_3 PF13917.1 CDJ64004.1 - 0.036 13.8 0.2 0.074 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_60s PF00428.14 CDJ64005.1 - 0.0082 16.5 27.9 0.057 13.8 8.2 2.4 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF4207 PF13904.1 CDJ64005.1 - 0.054 12.8 16.6 0.094 12.0 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) CDK5_activator PF03261.10 CDJ64005.1 - 0.064 12.5 10.6 0.078 12.3 7.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Zip PF02535.17 CDJ64005.1 - 0.15 11.0 9.9 0.19 10.7 6.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF572 PF04502.8 CDJ64005.1 - 0.27 10.4 9.4 0.3 10.2 6.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PPP4R2 PF09184.6 CDJ64005.1 - 0.92 9.0 10.0 1.2 8.6 7.0 1.1 1 0 0 1 1 1 0 PPP4R2 CAF-1_p150 PF11600.3 CDJ64005.1 - 1.6 8.0 17.7 2.4 7.4 12.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AUX_IAA PF02309.11 CDJ64005.1 - 3.3 7.3 7.0 5.2 6.7 4.8 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF1675 PF07897.6 CDJ64005.1 - 4.3 7.1 15.7 6.4 6.5 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF900 PF05990.7 CDJ64006.1 - 8e-18 64.6 0.0 7e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) DUF2722 PF10846.3 CDJ64006.1 - 0.004 16.2 1.0 0.44 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.3 CDJ64006.1 - 0.13 11.5 3.6 3.7 6.8 0.6 2.2 2 0 0 2 2 2 0 Spt20 family HAD PF12710.2 CDJ64007.1 - 1.2e-09 38.6 0.0 2.3e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDJ64007.1 - 1.4e-09 38.7 8.1 0.00011 22.6 0.2 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDJ64007.1 - 0.0054 16.3 0.0 0.012 15.1 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TFIIA PF03153.8 CDJ64007.1 - 4.9 6.9 32.8 0.17 11.7 2.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.8 CDJ64007.1 - 9.9 4.5 13.2 1.2 7.5 2.6 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF543 PF04418.7 CDJ64008.1 - 6.3e-05 22.8 0.1 9.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF543) GLTSCR1 PF15249.1 CDJ64010.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region CKS PF01111.14 CDJ64011.1 - 4.5e-07 29.5 0.8 7.5e-07 28.8 0.5 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribosomal_60s PF00428.14 CDJ64011.1 - 0.00013 22.2 1.5 0.00014 22.2 1.1 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 CDJ64011.1 - 2.7 7.8 9.5 3.9 7.3 6.6 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Peptidase_S15 PF02129.13 CDJ64012.1 - 0.53 9.6 10.1 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) RAP1 PF07218.6 CDJ64012.1 - 1.3 7.0 12.5 1.7 6.6 8.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-DHHC PF01529.15 CDJ64012.1 - 3.4 7.0 14.9 4.7 6.5 2.4 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase MAT1 PF06391.8 CDJ64012.1 - 8.7 5.8 32.0 1.1 8.7 5.6 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 zf-RING_UBOX PF13445.1 CDJ64013.1 - 1e-05 25.1 5.3 2.7e-05 23.7 0.6 3.5 2 0 0 2 2 2 1 RING-type zinc-finger HTH_38 PF13936.1 CDJ64014.1 - 0.0061 16.0 0.3 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Asp-B-Hydro_N PF05279.6 CDJ64014.1 - 1.1 9.0 7.7 0.18 11.5 0.6 2.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region NPR3 PF03666.8 CDJ64015.1 - 0.23 9.9 12.4 0.3 9.5 8.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4603 PF15376.1 CDJ64015.1 - 0.55 7.3 18.7 0.67 7.0 12.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Med15 PF09606.5 CDJ64015.1 - 1.2 7.2 25.7 1.5 6.9 17.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_pol_viral_N PF00242.12 CDJ64015.1 - 1.4 7.8 16.5 1.7 7.5 11.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain U1snRNP70_N PF12220.3 CDJ64015.1 - 2 8.8 8.4 1.1 9.5 1.9 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RAB3GAP2_N PF14655.1 CDJ64015.1 - 3.9 6.3 10.0 0.12 11.3 2.1 1.8 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2217 PF10265.4 CDJ64015.1 - 7.1 5.2 9.7 11 4.6 6.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF755 PF05501.6 CDJ64019.1 - 0.0072 16.3 14.7 0.0072 16.3 10.2 6.6 7 1 1 8 8 8 1 Domain of unknown function (DUF755) Epimerase_Csub PF13950.1 CDJ64019.1 - 0.07 13.0 0.3 0.74 9.7 0.0 2.6 2 0 0 2 2 2 0 UDP-glucose 4-epimerase C-term subunit LANC_like PF05147.8 CDJ64020.1 - 4.3e-32 111.0 3.2 2.5e-09 36.1 0.0 5.2 5 0 0 5 5 5 5 Lanthionine synthetase C-like protein EF-hand_7 PF13499.1 CDJ64021.1 - 0.007 16.4 0.0 0.017 15.2 0.0 1.6 1 1 1 2 2 2 1 EF-hand domain pair SHMT PF00464.14 CDJ64024.1 - 6.6e-154 512.0 0.0 1.2e-81 274.1 0.0 2.6 1 1 1 2 2 2 2 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CDJ64024.1 - 0.021 13.9 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase PI3_PI4_kinase PF00454.22 CDJ64025.1 - 1.4e-25 90.1 0.0 2.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Phe_tRNA-synt_N PF02912.13 CDJ64026.1 - 0.061 13.0 0.6 5.7 6.7 0.3 2.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain PC_rep PF01851.17 CDJ64027.1 - 2.6e-09 36.7 31.2 0.00029 20.8 0.1 8.9 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CDJ64027.1 - 0.0018 18.5 7.2 0.076 13.3 0.0 4.3 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 CDJ64027.1 - 0.55 10.7 7.3 69 4.1 0.1 5.1 4 0 0 4 4 4 0 HEAT-like repeat MGC-24 PF05283.6 CDJ64027.1 - 2.5 7.8 7.6 0.73 9.5 2.4 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Herpes_capsid PF06112.6 CDJ64027.1 - 6.2 6.8 11.3 0.32 11.0 2.2 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PCI PF01399.22 CDJ64028.1 - 1.1e-11 44.9 0.2 2.8e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 CDJ64028.1 - 0.032 14.1 0.1 0.62 10.1 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 CDJ64030.1 - 0.00028 20.6 0.5 0.011 15.5 0.2 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF736 PF05284.7 CDJ64030.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF736) Cohesin_HEAT PF12765.2 CDJ64031.1 - 0.022 14.7 4.4 1.5 8.8 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion zf-CCCH_2 PF14608.1 CDJ64032.1 - 3e-06 27.0 33.5 0.0093 15.9 4.8 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CDJ64032.1 - 0.0017 18.0 0.8 0.0017 18.0 0.5 4.0 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHH PF10283.4 CDJ64032.1 - 0.22 11.3 18.0 1.5 8.6 0.4 3.6 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif DUF1649 PF07855.7 CDJ64033.1 - 4e-05 23.3 0.0 0.13 11.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1649) Glycos_transf_1 PF00534.15 CDJ64034.1 - 4e-38 130.5 0.0 7.6e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CDJ64034.1 - 6.2e-22 78.4 0.8 3.3e-20 72.8 0.0 3.1 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CDJ64034.1 - 3.8e-15 56.0 2.2 2.5e-14 53.3 1.5 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.6 CDJ64034.1 - 4.7e-15 55.7 0.2 1.6e-12 47.4 0.2 2.5 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 CDJ64034.1 - 1.6e-13 50.9 0.0 3.6e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase_C PF02806.13 CDJ64034.1 - 3.3e-11 43.1 0.0 7.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_trans_1_2 PF13524.1 CDJ64034.1 - 0.00015 21.9 0.0 0.0004 20.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Collagen PF01391.13 CDJ64035.1 - 4.1e-05 23.0 35.6 8.9e-05 21.9 24.7 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) SpoIIE PF07228.7 CDJ64035.1 - 0.00022 20.9 0.0 0.00088 19.0 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CDJ64035.1 - 0.013 14.9 0.0 0.095 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C DUF2956 PF11169.3 CDJ64036.1 - 0.082 12.8 16.5 0.019 14.9 3.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2956) DUF2956 PF11169.3 CDJ64037.1 - 0.036 14.0 15.8 0.017 15.0 3.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2956) Apt1 PF10351.4 CDJ64037.1 - 4 6.1 15.5 8.2 5.1 10.8 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Syntaphilin PF15290.1 CDJ64038.1 - 1.8 7.9 10.4 0.055 12.9 2.4 1.8 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Herpes_gE PF02480.11 CDJ64038.1 - 2.4 6.3 11.1 1.2 7.3 5.5 1.8 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E TFIIA PF03153.8 CDJ64038.1 - 5.2 6.8 14.7 6.6 6.5 10.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyto_ox_2 PF02322.10 CDJ64038.1 - 6.5 5.8 13.6 7.9 5.5 9.4 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II PAT1 PF09770.4 CDJ64038.1 - 7 4.7 6.8 7.3 4.6 4.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF410 PF04190.8 CDJ64039.1 - 2.2e-08 33.9 0.0 3.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Ribosomal_60s PF00428.14 CDJ64041.1 - 4.9 7.6 9.2 0.81 10.1 3.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein CRAL_TRIO PF00650.15 CDJ64042.1 - 1.8e-11 43.8 0.0 2.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Utp14 PF04615.8 CDJ64042.1 - 0.81 7.7 48.0 1 7.4 33.3 1.0 1 0 0 1 1 1 0 Utp14 protein CRT10 PF08728.5 CDJ64042.1 - 0.99 7.3 5.6 1.1 7.1 3.9 1.2 1 0 0 1 1 1 0 CRT10 Nha1_C PF08619.5 CDJ64042.1 - 8.1 5.6 38.9 3.1 6.9 17.1 2.0 1 1 1 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Thioredoxin_8 PF13905.1 CDJ64043.1 - 6.3e-25 87.1 0.0 9.1e-25 86.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CDJ64043.1 - 0.026 14.2 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family RTC PF01137.16 CDJ64044.1 - 1.4e-29 102.4 0.0 1.2e-28 99.4 0.0 2.4 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CDJ64044.1 - 1.5e-07 31.3 3.4 1.2e-06 28.4 0.2 2.9 2 1 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain WD40 PF00400.27 CDJ64045.1 - 1.8e-40 135.3 24.8 1.8e-07 30.7 0.1 11.7 12 1 0 12 12 12 8 WD domain, G-beta repeat Nup160 PF11715.3 CDJ64045.1 - 6.2e-05 21.3 1.3 0.16 10.0 0.0 4.0 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Utp12 PF04003.7 CDJ64045.1 - 0.00011 22.0 4.2 0.00026 20.8 0.1 2.5 2 0 0 2 2 2 1 Dip2/Utp12 Family Gti1_Pac2 PF09729.4 CDJ64045.1 - 0.092 12.6 2.5 0.27 11.0 0.2 2.7 3 0 0 3 3 3 0 Gti1/Pac2 family Peptidase_S49_N PF08496.5 CDJ64045.1 - 1.8 8.3 7.4 0.45 10.2 1.4 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MFS_1 PF07690.11 CDJ64046.1 - 3.9e-30 104.7 25.9 3.8e-22 78.4 1.5 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily YjgP_YjgQ PF03739.9 CDJ64046.1 - 1.9 7.1 0.0 1.9 7.1 0.0 6.0 2 1 0 2 2 2 0 Predicted permease YjgP/YjgQ family CPSase_L_D2 PF02786.12 CDJ64048.1 - 3.4e-108 359.7 0.0 3.7e-77 258.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CDJ64048.1 - 8.6e-41 138.5 0.0 2.3e-40 137.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.23 CDJ64048.1 - 1.1e-40 139.1 0.0 2.9e-40 137.7 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 CDJ64048.1 - 2.4e-40 137.0 0.0 5.3e-40 135.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain ATP-grasp_4 PF13535.1 CDJ64048.1 - 7.8e-34 117.0 0.4 6.7e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 CDJ64048.1 - 3e-32 111.0 0.1 9.1e-15 54.7 0.0 3.5 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 CDJ64048.1 - 2.2e-19 69.3 0.0 4.5e-11 42.0 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CDJ64048.1 - 2.2e-16 59.7 0.0 8.2e-08 31.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CDJ64048.1 - 7.6e-16 58.1 0.1 8.5e-07 28.5 0.1 2.9 2 1 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 CDJ64048.1 - 2.2e-11 43.5 0.0 2.2e-10 40.3 0.0 2.8 2 1 0 2 2 2 1 MGS-like domain Peptidase_C26 PF07722.8 CDJ64048.1 - 1.5e-06 27.8 0.0 0.00021 20.8 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CDJ64048.1 - 3.6e-05 23.6 0.1 0.082 12.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 CDJ64048.1 - 0.00037 20.0 0.0 0.35 10.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 CDJ64048.1 - 0.0018 17.5 0.1 0.0044 16.2 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain DJ-1_PfpI PF01965.19 CDJ64048.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 DJ-1/PfpI family WD40 PF00400.27 CDJ64049.1 - 0.00083 19.1 2.1 0.0016 18.2 0.3 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Glyco_tran_28_C PF04101.11 CDJ64050.1 - 3.5e-17 62.5 0.0 5.1e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DDHD PF02862.12 CDJ64051.1 - 0.89 9.3 8.0 1.2 8.8 5.6 1.3 1 0 0 1 1 1 0 DDHD domain DUF2796 PF10986.3 CDJ64051.1 - 5.8 6.8 22.1 7.9 6.4 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SNF2_N PF00176.18 CDJ64052.1 - 2.2e-18 66.1 0.0 2.4e-15 56.0 0.0 2.8 3 0 0 3 3 3 2 SNF2 family N-terminal domain zf-C4_Topoisom PF01396.14 CDJ64052.1 - 4e-07 29.4 3.8 1.4e-06 27.7 2.6 1.9 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger HNH PF01844.18 CDJ64052.1 - 6.4e-05 22.7 0.0 0.00026 20.8 0.0 2.1 1 0 0 1 1 1 1 HNH endonuclease DEAD PF00270.24 CDJ64052.1 - 9.2e-05 21.9 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ64052.1 - 0.02 14.7 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Alpha-L-AF_C PF06964.7 CDJ64054.1 - 0.02 14.6 0.0 0.032 14.0 0.0 1.3 1 1 0 1 1 1 0 Alpha-L-arabinofuranosidase C-terminus FixG_C PF11614.3 CDJ64054.1 - 0.025 14.6 0.1 0.042 13.9 0.1 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF605 PF04652.11 CDJ64054.1 - 3.7 6.8 12.7 4.6 6.5 8.8 1.1 1 0 0 1 1 1 0 Vta1 like Cyclin PF08613.6 CDJ64055.1 - 1.7e-29 103.1 4.2 2.5e-29 102.6 0.1 2.7 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CDJ64055.1 - 2.7e-06 26.9 0.1 2.7e-06 26.9 0.0 3.3 4 1 0 4 4 4 1 Cyclin, N-terminal domain GHMP_kinases_N PF00288.21 CDJ64055.1 - 0.00034 20.6 0.1 0.001 19.1 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain TauE PF01925.14 CDJ64056.1 - 6.2e-18 65.1 24.3 2.6e-14 53.2 5.1 3.2 3 0 0 3 3 3 3 Sulfite exporter TauE/SafE PAN_4 PF14295.1 CDJ64057.1 - 1.9e-53 177.9 82.7 1.8e-08 33.9 0.2 12.1 12 0 0 12 12 12 11 PAN domain PAN_1 PF00024.21 CDJ64057.1 - 3.3e-47 158.1 54.1 6.2e-07 29.0 1.2 11.7 9 3 2 12 12 12 10 PAN domain PAN_3 PF08277.7 CDJ64057.1 - 0.013 15.1 1.0 0.013 15.1 0.7 10.2 11 0 0 11 11 11 0 PAN-like domain AdoMetDC_leader PF08132.6 CDJ64057.1 - 2.6 8.0 12.4 2.6 8.0 0.8 2.9 2 0 0 2 2 2 0 S-adenosyl-l-methionine decarboxylase leader peptide MASE1 PF05231.9 CDJ64057.1 - 2.8 6.8 15.9 0.11 11.4 6.4 1.9 2 0 0 2 2 2 0 MASE1 TSP_1 PF00090.14 CDJ64058.1 - 4.8e-06 26.5 3.1 4.8e-06 26.5 2.1 4.4 5 0 0 5 5 5 1 Thrombospondin type 1 domain PCI PF01399.22 CDJ64060.1 - 4.4e-07 30.1 0.0 8.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF3633 PF12315.3 CDJ64060.1 - 0.0018 17.6 3.1 0.027 13.7 1.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3633) FeoC PF09012.5 CDJ64060.1 - 0.018 14.7 0.1 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator SR-25 PF10500.4 CDJ64060.1 - 1.7 8.0 15.0 0.1 12.0 6.5 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_S10 PF00338.17 CDJ64061.1 - 2.4e-10 40.1 1.6 9.9e-09 34.9 0.2 3.6 2 1 0 2 2 2 1 Ribosomal protein S10p/S20e SR-25 PF10500.4 CDJ64061.1 - 0.00051 19.5 16.3 0.00051 19.5 11.3 10.9 6 3 2 9 9 9 3 Nuclear RNA-splicing-associated protein TPR_1 PF00515.23 CDJ64061.1 - 0.00094 18.6 5.9 1 9.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ64061.1 - 0.0084 15.9 16.5 0.23 11.4 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat RNA_pol_Rpc4 PF05132.9 CDJ64062.1 - 4.9e-11 42.7 0.4 4.9e-11 42.7 0.3 6.0 4 2 0 4 4 4 2 RNA polymerase III RPC4 BPL_LplA_LipB PF03099.14 CDJ64063.1 - 1.9e-11 44.0 0.9 9.6e-08 32.0 0.1 2.7 2 0 0 2 2 2 2 Biotin/lipoate A/B protein ligase family Diphthamide_syn PF01866.12 CDJ64064.1 - 7.8e-53 179.7 0.0 2.5e-33 115.6 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein MIP-T3 PF10243.4 CDJ64064.1 - 0.035 12.5 5.0 0.045 12.2 3.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 E1-E2_ATPase PF00122.15 CDJ64066.1 - 0.00015 20.8 0.1 0.00063 18.8 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Suf PF05843.9 CDJ64066.1 - 0.007 16.1 2.2 0.0083 15.8 1.5 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ64066.1 - 0.0093 15.3 0.2 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Spt20 family Band_3_cyto PF07565.8 CDJ64066.1 - 0.02 14.3 0.3 0.027 13.9 0.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BaxI_1 PF12811.2 CDJ64066.1 - 0.066 12.3 0.5 0.09 11.9 0.3 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like FHIPEP PF00771.15 CDJ64066.1 - 0.075 11.3 0.2 0.097 10.9 0.1 1.1 1 0 0 1 1 1 0 FHIPEP family DUF2971 PF11185.3 CDJ64066.1 - 0.085 13.5 0.5 0.18 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2971) FliP PF00813.15 CDJ64066.1 - 0.2 11.3 3.3 0.35 10.5 2.1 1.4 1 1 0 1 1 1 0 FliP family Med15 PF09606.5 CDJ64066.1 - 0.21 9.7 16.4 0.27 9.3 11.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3533 PF12051.3 CDJ64066.1 - 0.34 9.5 3.3 0.57 8.8 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SprA-related PF12118.3 CDJ64066.1 - 0.45 9.8 15.8 0.68 9.1 10.9 1.2 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.8 CDJ64066.1 - 0.48 10.4 8.4 0.17 11.9 3.2 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDJ64068.1 - 0.00051 18.4 29.4 0.00051 18.4 20.4 2.1 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_gyraseB PF00204.20 CDJ64069.1 - 5.4e-22 77.8 0.3 1.4e-15 56.9 0.6 4.8 5 0 0 5 5 5 2 DNA gyrase B DNA_gyraseB_C PF00986.16 CDJ64069.1 - 3.3e-17 61.9 0.2 8.4e-17 60.6 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.17 CDJ64069.1 - 3.4e-14 52.6 12.0 3.4e-14 52.6 8.3 4.4 4 2 0 4 4 4 1 Toprim domain SR-25 PF10500.4 CDJ64069.1 - 1.8e-05 24.3 10.7 1.8e-05 24.3 7.4 5.9 4 2 2 6 6 6 2 Nuclear RNA-splicing-associated protein Rad51 PF08423.6 CDJ64070.1 - 6.4e-110 366.0 0.0 7.2e-110 365.8 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CDJ64070.1 - 1.8e-07 30.7 0.0 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Tbf5 PF06331.7 CDJ64071.1 - 1.9e-22 78.7 0.2 2.3e-22 78.5 0.2 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Sec23_trunk PF04811.10 CDJ64072.1 - 7.4e-37 127.0 0.0 3.6e-30 105.1 0.0 3.2 2 1 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CDJ64072.1 - 8.4e-31 106.3 0.1 2.5e-30 104.8 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CDJ64072.1 - 5.8e-06 25.6 0.1 1.3e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Actin PF00022.14 CDJ64073.1 - 5e-26 91.0 0.0 4.6e-16 58.2 0.0 2.7 2 1 0 2 2 2 2 Actin IZUMO PF15005.1 CDJ64075.1 - 0.099 12.6 1.0 4 7.4 1.0 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion Rad21_Rec8 PF04824.11 CDJ64076.1 - 7.1e-06 25.1 0.0 2.2e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SPRY PF00622.23 CDJ64077.1 - 2.3e-05 24.4 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 SPRY domain zf-RING_2 PF13639.1 CDJ64078.1 - 1.1e-10 41.1 9.0 2.6e-10 39.9 1.9 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDJ64078.1 - 8.2e-09 35.3 4.9 9.5e-08 31.9 1.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ64078.1 - 1.5e-07 31.0 7.1 1.9e-07 30.6 0.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CDJ64078.1 - 3.5e-06 26.5 2.1 3.5e-06 26.5 1.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDJ64078.1 - 4.4e-06 26.7 3.0 2.1e-05 24.5 0.2 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDJ64078.1 - 1.4e-05 24.6 1.1 1.4e-05 24.6 0.8 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CDJ64078.1 - 0.089 12.3 8.8 0.039 13.5 0.7 3.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Ycf1 PF05758.7 CDJ64078.1 - 0.13 10.0 2.0 0.17 9.5 1.4 1.1 1 0 0 1 1 1 0 Ycf1 zf-C3HC4_4 PF15227.1 CDJ64078.1 - 0.31 10.9 10.9 0.079 12.8 3.3 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CDJ64078.1 - 1.2 8.9 4.4 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FimP PF09766.4 CDJ64078.1 - 1.5 7.7 13.2 2.9 6.8 9.1 1.4 1 0 0 1 1 1 0 Fms-interacting protein zf-P11 PF03854.9 CDJ64078.1 - 4 6.9 8.0 0.3 10.5 1.5 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_UBOX PF13445.1 CDJ64078.1 - 4.2 7.1 15.8 0.064 12.9 3.3 3.2 3 1 0 3 3 3 0 RING-type zinc-finger HEAT PF02985.17 CDJ64079.1 - 0.045 13.8 5.3 13 6.1 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Ribosomal_S15 PF00312.17 CDJ64080.1 - 4.7e-16 58.3 1.0 7.9e-16 57.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Ank_2 PF12796.2 CDJ64081.1 - 2.6e-68 226.4 20.0 8.3e-19 67.7 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ64081.1 - 5.9e-35 117.3 14.4 3.4e-05 23.4 0.0 8.1 7 1 1 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 CDJ64081.1 - 6.4e-28 94.0 4.0 0.00067 19.6 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 CDJ64081.1 - 9.2e-28 95.6 6.2 7e-09 35.6 0.9 5.7 4 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDJ64081.1 - 9e-25 86.5 2.2 1e-08 35.4 0.0 6.3 2 1 4 7 7 7 4 Ankyrin repeats (many copies) TPR_11 PF13414.1 CDJ64081.1 - 1.2e-12 47.2 0.9 2.8e-07 30.0 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 CDJ64081.1 - 0.0039 17.2 0.1 2.9 8.3 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ64081.1 - 0.027 15.0 3.5 2.3 9.0 0.0 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 CDJ64081.1 - 0.16 12.2 8.0 0.59 10.4 4.0 2.8 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Ten_N PF06484.7 CDJ64081.1 - 0.48 9.4 4.7 0.99 8.4 3.2 1.5 1 0 0 1 1 1 0 Teneurin Intracellular Region TPR_16 PF13432.1 CDJ64081.1 - 1 10.0 5.8 12 6.7 0.3 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat UQ_con PF00179.21 CDJ64082.1 - 1.8e-51 173.2 0.0 2.2e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDJ64082.1 - 2.2e-05 24.2 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CDJ64082.1 - 0.022 14.6 0.2 0.031 14.1 0.1 1.5 1 1 0 1 1 1 0 RWD domain Ring_hydroxyl_B PF00866.13 CDJ64082.1 - 0.09 12.4 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Ring hydroxylating beta subunit GET2 PF08690.5 CDJ64083.1 - 0.22 10.7 0.3 0.33 10.1 0.2 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 APG6 PF04111.7 CDJ64084.1 - 2.4e-70 237.0 0.0 3.1e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF4164 PF13747.1 CDJ64084.1 - 0.057 13.5 7.3 0.16 12.1 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DivIC PF04977.10 CDJ64084.1 - 0.9 9.0 4.2 1.9 8.0 2.9 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF641 PF04859.7 CDJ64084.1 - 2 8.2 8.1 0.9 9.2 0.1 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Abi_C PF14355.1 CDJ64085.1 - 0.024 14.5 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Abortive infection C-terminus OTU PF02338.14 CDJ64088.1 - 4.1e-11 43.5 0.0 1e-10 42.2 0.0 1.6 1 1 0 1 1 1 1 OTU-like cysteine protease Sec1 PF00995.18 CDJ64090.1 - 0.0066 15.1 0.0 0.0078 14.8 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Mito_carr PF00153.22 CDJ64091.1 - 1e-24 86.0 11.3 1.2e-08 34.5 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein TEX13 PF15186.1 CDJ64091.1 - 0.03 13.8 1.2 0.069 12.7 0.8 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family FliD_N PF02465.13 CDJ64091.1 - 0.1 12.9 6.8 0.28 11.5 4.7 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF1682 PF07946.9 CDJ64092.1 - 2.2e-48 164.7 0.4 2.9e-48 164.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DDHD PF02862.12 CDJ64092.1 - 2.5 7.8 6.3 4 7.1 4.4 1.3 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 CDJ64092.1 - 8.4 3.9 10.7 11 3.5 7.4 1.1 1 0 0 1 1 1 0 Ycf1 Chorismate_bind PF00425.13 CDJ64094.1 - 1.1e-22 80.5 0.0 1.8e-14 53.7 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.8 CDJ64094.1 - 4.8e-08 33.1 0.9 1.5e-05 25.0 0.1 2.9 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region GATase PF00117.23 CDJ64094.1 - 5.8e-07 29.1 0.1 9.5e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase PF00117.23 CDJ64095.1 - 6.9e-16 58.2 0.0 8.6e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CDJ64095.1 - 0.19 11.1 0.3 0.23 10.8 0.2 1.5 1 1 0 1 1 1 0 Peptidase C26 Peptidase_M14 PF00246.19 CDJ64096.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Zinc carboxypeptidase Spt20 PF12090.3 CDJ64097.1 - 0.00021 20.6 9.2 0.22 10.8 0.2 3.2 3 0 0 3 3 3 3 Spt20 family RFXA_RFXANK_bdg PF15289.1 CDJ64097.1 - 0.018 15.2 2.8 0.018 15.2 1.9 3.6 3 0 0 3 3 3 0 Regulatory factor X-associated C-terminal binding domain APC_CDC26 PF10471.4 CDJ64097.1 - 0.22 12.2 42.7 0.48 11.1 3.2 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 Neur_chan_memb PF02932.11 CDJ64097.1 - 2.9 7.7 6.9 36 4.1 4.8 2.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SGT1 PF07093.6 CDJ64097.1 - 5.9 5.1 11.2 4.7 5.4 0.0 2.9 3 0 0 3 3 3 0 SGT1 protein Acyltransferase PF01553.16 CDJ64099.1 - 2.4e-05 23.7 0.1 5.3e-05 22.6 0.0 1.6 1 1 1 2 2 2 1 Acyltransferase DUF2387 PF09526.5 CDJ64100.1 - 0.015 15.1 1.3 0.19 11.6 0.1 2.7 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) BCNT PF07572.7 CDJ64101.1 - 5.2e-10 39.1 0.5 1.1e-09 38.0 0.1 1.6 1 1 0 1 1 1 1 Bucentaur or craniofacial development DUF1690 PF07956.6 CDJ64101.1 - 0.0068 16.3 0.8 0.0081 16.1 0.6 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) RskA PF10099.4 CDJ64101.1 - 0.25 11.0 13.7 0.35 10.6 9.5 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Rifin_STEVOR PF02009.11 CDJ64101.1 - 2.6 7.5 8.7 3.1 7.3 6.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Yippee-Mis18 PF03226.9 CDJ64102.1 - 9.4e-18 64.0 0.2 1.2e-17 63.7 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-P11 PF03854.9 CDJ64102.1 - 0.0049 16.2 0.9 0.011 15.2 0.6 1.5 1 0 0 1 1 1 1 P-11 zinc finger zf-CHY PF05495.7 CDJ64102.1 - 0.0066 16.5 6.5 0.02 15.0 4.5 1.8 1 1 0 1 1 1 1 CHY zinc finger zinc_ribbon_6 PF14599.1 CDJ64102.1 - 0.0097 15.6 0.2 0.0097 15.6 0.1 2.1 2 0 0 2 2 2 1 Zinc-ribbon GFA PF04828.9 CDJ64102.1 - 0.023 14.6 3.7 1.1 9.2 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 CDJ64102.1 - 0.16 11.8 2.9 5.1 6.9 0.1 2.2 1 1 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 CDJ64102.1 - 0.37 10.2 4.0 6 6.4 0.1 2.6 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.4 CDJ64102.1 - 5 7.1 5.8 1.2 9.1 0.3 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) Exonuc_VII_L PF02601.10 CDJ64104.1 - 0.044 12.9 8.9 0.046 12.9 6.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 CDJ64104.1 - 0.34 8.7 15.8 0.45 8.3 11.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GSCFA PF08885.6 CDJ64104.1 - 0.63 9.5 8.6 0.92 9.0 6.0 1.2 1 0 0 1 1 1 0 GSCFA family ExbD PF02472.11 CDJ64104.1 - 0.88 9.5 9.9 1.4 8.8 6.8 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF506 PF04720.7 CDJ64104.1 - 3.5 7.1 9.3 4.9 6.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) eIF-3_zeta PF05091.7 CDJ64104.1 - 3.9 5.9 16.5 5.4 5.5 11.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) N6_N4_Mtase PF01555.13 CDJ64104.1 - 5.9 6.3 5.7 47 3.3 4.2 1.9 1 1 0 1 1 1 0 DNA methylase XAP5 PF04921.9 CDJ64104.1 - 9.8 5.6 14.3 14 5.1 9.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Ricin_B_lectin PF00652.17 CDJ64106.1 - 9.8e-13 48.2 0.3 1.2e-08 35.0 0.2 3.4 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CDJ64106.1 - 1.1e-10 40.8 0.2 2.1e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_2 PF10111.4 CDJ64106.1 - 3.3e-06 26.4 0.0 8.2e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CDJ64106.1 - 4e-06 26.6 0.0 7.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CDJ64106.1 - 1.3e-05 25.0 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CDJ64106.1 - 0.013 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Suf PF05843.9 CDJ64106.1 - 0.098 12.3 3.7 0.14 11.8 2.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ64106.1 - 0.11 11.8 4.0 0.19 11.0 2.8 1.4 1 0 0 1 1 1 0 Spt20 family DUF1566 PF07603.6 CDJ64106.1 - 0.2 11.4 6.8 0.51 10.0 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) DUF4175 PF13779.1 CDJ64106.1 - 0.76 7.4 13.3 1 6.9 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Shadoo PF14999.1 CDJ64107.1 - 0.012 15.4 0.1 0.012 15.4 0.0 3.5 2 1 0 2 2 1 0 Shadow of prion protein, neuroprotective DUF1777 PF08648.7 CDJ64107.1 - 0.08 12.6 11.0 0.13 12.0 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CDK5_activator PF03261.10 CDJ64107.1 - 0.092 12.0 11.1 0.12 11.7 7.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SOBP PF15279.1 CDJ64107.1 - 0.1 12.9 13.6 0.13 12.5 9.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2956 PF11169.3 CDJ64107.1 - 0.12 12.3 20.7 0.038 13.9 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Med19 PF10278.4 CDJ64107.1 - 0.29 10.8 15.4 0.24 11.0 5.9 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF2366 PF10171.4 CDJ64107.1 - 0.43 10.0 2.6 3.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2366) SAPS PF04499.10 CDJ64107.1 - 0.66 8.5 11.2 0.86 8.1 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CD20 PF04103.10 CDJ64107.1 - 2.2 8.1 8.7 0.45 10.4 1.5 2.5 1 1 1 2 2 2 0 CD20-like family PAT1 PF09770.4 CDJ64107.1 - 2.6 6.1 46.0 3.1 5.9 31.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.6 CDJ64107.1 - 4.9 5.3 13.6 5.9 5.0 9.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 Peroxin-13_N PF04088.8 CDJ64107.1 - 5.4 6.9 11.2 6.5 6.6 2.2 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region PLRV_ORF5 PF01690.12 CDJ64108.1 - 0.0016 17.6 21.9 0.0017 17.6 15.2 1.2 1 0 0 1 1 1 1 Potato leaf roll virus readthrough protein SAPS PF04499.10 CDJ64108.1 - 0.0081 14.8 23.7 0.009 14.6 16.4 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein HlyD_2 PF12700.2 CDJ64108.1 - 0.017 14.2 23.6 0.018 14.2 16.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Macoilin PF09726.4 CDJ64108.1 - 0.11 10.7 29.8 0.15 10.3 20.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Herpes_UL87 PF03043.9 CDJ64108.1 - 0.18 10.1 12.9 0.17 10.2 9.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF966 PF06136.8 CDJ64108.1 - 0.24 10.7 29.0 0.35 10.2 20.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mem_trans PF03547.13 CDJ64108.1 - 0.56 8.4 12.8 0.7 8.1 8.8 1.2 1 0 0 1 1 1 0 Membrane transport protein LMBR1 PF04791.11 CDJ64108.1 - 0.72 8.3 13.6 0.85 8.1 9.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CRT10 PF08728.5 CDJ64108.1 - 0.76 7.6 15.4 0.66 7.8 10.7 1.0 1 0 0 1 1 1 0 CRT10 CDC45 PF02724.9 CDJ64108.1 - 2.3 6.1 34.9 3.2 5.6 24.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.6 CDJ64108.1 - 2.9 7.0 16.3 81 2.2 11.3 2.0 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Exonuc_VII_L PF02601.10 CDJ64108.1 - 7.5 5.6 30.5 8.9 5.4 21.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit APC_CDC26 PF10471.4 CDJ64109.1 - 0.041 14.6 0.5 0.057 14.1 0.3 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 AF-4 PF05110.8 CDJ64110.1 - 0.0017 16.3 10.0 0.0021 16.0 6.9 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein HTH_32 PF13565.1 CDJ64110.1 - 0.097 13.4 5.5 0.1 13.4 0.3 3.0 1 1 1 2 2 2 0 Homeodomain-like domain Suf PF05843.9 CDJ64111.1 - 0.089 12.5 12.9 0.081 12.6 3.7 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SAGA-Tad1 PF12767.2 CDJ64111.1 - 0.1 12.2 6.1 0.19 11.3 1.2 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Spore_coat_CotO PF14153.1 CDJ64111.1 - 1.5 8.2 13.3 1 8.8 4.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Senescence_reg PF04520.8 CDJ64111.1 - 1.5 9.2 14.6 3.9 7.9 3.2 2.3 2 0 0 2 2 2 0 Senescence regulator DDHD PF02862.12 CDJ64111.1 - 2.8 7.6 6.7 3.1 7.5 2.1 2.0 2 0 0 2 2 2 0 DDHD domain CDK5_activator PF03261.10 CDJ64111.1 - 5.1 6.3 10.2 0.91 8.8 0.6 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Med15 PF09606.5 CDJ64112.1 - 6.3e-05 21.4 63.8 6.3e-05 21.4 44.2 4.3 4 1 0 4 4 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_env PF01673.13 CDJ64112.1 - 0.43 9.0 15.5 1.1 7.7 9.2 2.1 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein Mem_trans PF03547.13 CDJ64112.1 - 0.8 7.9 6.5 0.55 8.4 3.3 1.6 2 0 0 2 2 2 0 Membrane transport protein Zip PF02535.17 CDJ64112.1 - 1.1 8.1 13.2 1.2 8.1 7.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter GAGA_bind PF06217.7 CDJ64112.1 - 1.7 8.5 24.9 1.4 8.7 13.5 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family DUF2052 PF09747.4 CDJ64112.1 - 2 8.3 32.2 1.2 9.0 17.3 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.11 CDJ64112.1 - 3.1 7.5 23.1 3.5 7.4 13.3 2.4 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Parvo_coat PF00740.13 CDJ64112.1 - 4 6.2 32.8 1.6 7.5 18.9 2.2 2 0 0 2 2 2 0 Parvovirus coat protein VP2 LMBR1 PF04791.11 CDJ64112.1 - 4.1 5.8 5.4 7 5.1 3.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Tim54 PF11711.3 CDJ64112.1 - 5.8 5.4 15.9 4.5 5.7 8.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 CDJ64112.1 - 8.3 6.2 24.6 5.2 6.8 12.9 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDJ64112.1 - 8.8 6.0 23.7 2.1 8.0 10.6 2.8 3 0 0 3 3 3 0 DDHD domain Pkinase PF00069.20 CDJ64113.1 - 2e-30 105.7 0.0 2.7e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64113.1 - 4.1e-17 62.0 0.2 5.2e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDJ64113.1 - 0.00017 21.4 0.7 0.061 13.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family AP2 PF00847.15 CDJ64114.1 - 1.7e-05 24.8 1.1 5e-05 23.3 0.7 1.8 1 0 0 1 1 1 1 AP2 domain Peptidase_S8 PF00082.17 CDJ64115.1 - 1.2e-12 47.5 0.5 2.3e-12 46.6 0.1 1.5 2 0 0 2 2 2 1 Subtilase family PRMT5 PF05185.11 CDJ64116.1 - 7.7e-06 25.0 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_3 PF01596.12 CDJ64116.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 CDJ64116.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CDJ64116.1 - 0.11 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Serpin PF00079.15 CDJ64117.1 - 1e-77 261.8 0.3 1.2e-77 261.5 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) F-box-like PF12937.2 CDJ64119.1 - 0.21 11.3 2.1 1.4 8.7 0.2 2.6 2 0 0 2 2 2 0 F-box-like DUF3533 PF12051.3 CDJ64119.1 - 3 6.5 3.4 9.1 4.9 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MORN PF02493.15 CDJ64120.1 - 2.3e-92 297.5 101.3 4e-09 35.6 2.1 14.3 14 0 0 14 14 14 14 MORN repeat CPSase_sm_chain PF00988.17 CDJ64120.1 - 1.1 8.7 4.7 45 3.5 0.0 4.2 5 0 0 5 5 5 0 Carbamoyl-phosphate synthase small chain, CPSase domain Helicase_C PF00271.26 CDJ64121.1 - 3e-16 59.0 0.0 1.4e-15 56.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDJ64121.1 - 8.2e-15 54.7 0.0 1.9e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDJ64121.1 - 6e-05 22.9 0.0 6e-05 22.9 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.12 CDJ64121.1 - 1.8 7.9 8.3 0.073 12.4 0.4 2.2 2 0 0 2 2 2 0 Thymidylate kinase Helicase_C_2 PF13307.1 CDJ64122.1 - 1.8e-41 141.8 0.1 1.8e-41 141.8 0.1 3.0 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 CDJ64122.1 - 2.2e-23 82.5 9.6 8.1e-18 64.4 0.0 3.3 3 0 0 3 3 3 2 DEAD_2 CDC73 PF05179.9 CDJ64123.1 - 4.1e-28 98.5 0.0 7.2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family DUF1635 PF07795.6 CDJ64123.1 - 0.075 12.4 0.1 0.89 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) TRAPP PF04051.11 CDJ64125.1 - 2.6e-32 111.4 0.0 3.6e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_60s PF00428.14 CDJ64125.1 - 0.0063 16.8 1.6 0.0063 16.8 1.1 4.0 4 0 0 4 4 4 1 60s Acidic ribosomal protein Sporozoite_P67 PF05642.6 CDJ64126.1 - 0.36 8.6 0.9 3.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RdRP PF05183.7 CDJ64127.1 - 3e-25 88.9 0.0 2.3e-22 79.4 0.0 2.0 1 1 1 2 2 2 2 RNA dependent RNA polymerase Peptidase_M18 PF02127.10 CDJ64127.1 - 0.13 10.6 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) Transp_Tc5_C PF04236.10 CDJ64127.1 - 0.23 11.7 1.5 1.8 8.8 0.2 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF4651 PF15513.1 CDJ64128.1 - 0.032 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) RRM_1 PF00076.17 CDJ64128.1 - 0.094 12.3 0.0 1.1 8.9 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 CDJ64129.1 - 6.7e-15 55.0 0.3 2.3e-14 53.2 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CDJ64129.1 - 2.1e-09 37.2 0.0 5.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 SR-25 PF10500.4 CDJ64129.1 - 0.016 14.7 1.4 0.016 14.7 1.0 4.1 3 1 1 4 4 4 0 Nuclear RNA-splicing-associated protein AAA PF00004.24 CDJ64129.1 - 0.099 12.8 0.1 0.32 11.2 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Abhydrolase_2 PF02230.11 CDJ64130.1 - 5e-39 133.9 0.0 9.1e-38 129.8 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CDJ64130.1 - 1.4e-12 47.5 0.0 2.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CDJ64130.1 - 2.6e-09 36.8 0.0 4.8e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CDJ64130.1 - 1.7e-06 28.0 1.3 3.1e-06 27.2 0.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CDJ64130.1 - 0.00014 21.5 0.2 0.00032 20.3 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDJ64130.1 - 0.0015 17.8 0.5 1.3 8.2 0.0 2.5 1 1 0 2 2 2 2 Prolyl oligopeptidase family DUF2974 PF11187.3 CDJ64130.1 - 0.017 14.5 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase_phd PF10503.4 CDJ64130.1 - 0.022 14.0 0.3 0.066 12.4 0.0 1.8 1 1 1 2 2 2 0 Esterase PHB depolymerase DUF2048 PF09752.4 CDJ64130.1 - 0.063 12.1 0.7 0.12 11.2 0.5 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_1 PF00561.15 CDJ64130.1 - 0.077 12.5 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 CDJ64130.1 - 0.08 11.2 0.0 0.15 10.2 0.0 1.3 1 1 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.20 CDJ64130.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 CDJ64131.1 - 1.2e-75 254.0 0.0 1.6e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64131.1 - 1.7e-34 119.0 0.0 2.5e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CDJ64131.1 - 7.5e-27 90.5 14.3 3.3e-07 29.1 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 CDJ64131.1 - 3.5e-25 87.9 3.2 1.8e-12 47.2 0.8 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CDJ64131.1 - 1.7e-22 77.6 6.8 3.3e-07 29.3 0.1 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CDJ64131.1 - 3e-22 76.4 4.3 1.2e-05 24.7 0.0 5.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CDJ64131.1 - 2.1e-21 75.3 11.1 2.4e-08 33.4 1.0 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 CDJ64131.1 - 6.8e-06 25.9 0.2 0.011 15.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CDJ64131.1 - 1.2e-05 24.9 1.4 0.094 12.4 0.4 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CDJ64131.1 - 0.00049 20.1 0.3 0.78 9.7 0.0 3.0 2 1 2 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.1 CDJ64131.1 - 0.0015 17.5 0.0 0.0098 14.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CDJ64131.1 - 0.0058 16.3 2.3 0.059 13.0 0.0 3.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CDJ64131.1 - 0.056 12.4 0.0 0.15 11.0 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Collagen PF01391.13 CDJ64132.1 - 0.74 9.4 6.5 1.6 8.3 4.5 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) 7tm_1 PF00001.16 CDJ64134.1 - 1.6 7.8 11.1 1.4 8.0 0.0 3.8 3 2 1 4 4 4 0 7 transmembrane receptor (rhodopsin family) DUF3881 PF12997.2 CDJ64134.1 - 8.9 5.2 3.5 26 3.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) GCV_H PF01597.14 CDJ64135.1 - 2.7e-22 78.6 0.0 1.2e-17 63.7 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CDJ64135.1 - 0.0023 17.5 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF2407 PF10302.4 CDJ64136.1 - 0.23 11.7 0.0 0.23 11.7 0.0 4.4 4 2 1 5 5 5 0 DUF2407 ubiquitin-like domain WBP-1 PF11669.3 CDJ64136.1 - 0.33 11.0 0.0 0.33 11.0 0.0 4.8 4 1 0 4 4 4 0 WW domain-binding protein 1 Herpes_UL87 PF03043.9 CDJ64136.1 - 3 6.1 10.7 0.11 10.9 2.2 2.3 3 1 1 4 4 4 0 Herpesvirus UL87 family RabGAP-TBC PF00566.13 CDJ64138.1 - 4.6e-41 140.6 5.9 4.5e-40 137.4 3.4 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain HI0933_like PF03486.9 CDJ64139.1 - 0.0053 15.2 0.6 0.0063 15.0 0.4 1.0 1 0 0 1 1 1 1 HI0933-like protein Ribosomal_S8e PF01201.17 CDJ64142.1 - 9.9e-50 168.0 0.2 1.1e-49 167.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DNA_repr_REX1B PF14966.1 CDJ64143.1 - 0.92 9.9 7.5 0.26 11.7 0.8 3.2 3 1 1 4 4 4 0 DNA repair REX1-B Myosin_head PF00063.16 CDJ64145.1 - 5.8e-09 34.5 51.3 2.1e-07 29.4 0.5 5.4 2 2 1 3 3 3 2 Myosin head (motor domain) FimP PF09766.4 CDJ64145.1 - 0.00022 20.4 38.9 0.018 14.1 12.0 3.3 3 0 0 3 3 3 3 Fms-interacting protein AAA_11 PF13086.1 CDJ64145.1 - 0.00039 20.0 19.4 0.0019 17.8 2.2 2.3 2 0 0 2 2 2 2 AAA domain Herpes_UL87 PF03043.9 CDJ64145.1 - 0.0019 16.6 0.3 0.026 12.9 0.2 2.5 1 1 0 1 1 1 1 Herpesvirus UL87 family IncA PF04156.9 CDJ64145.1 - 0.0079 15.8 4.1 0.0079 15.8 2.8 5.0 5 1 0 5 5 3 1 IncA protein SAPS PF04499.10 CDJ64145.1 - 0.089 11.4 17.5 0.81 8.2 7.3 2.5 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein Suf PF05843.9 CDJ64145.1 - 0.14 11.8 40.0 0.24 11.1 3.7 3.2 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 CDJ64145.1 - 1.6 8.4 41.8 1.5 8.5 11.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) LMBR1 PF04791.11 CDJ64145.1 - 1.6 7.1 7.1 0.19 10.3 0.9 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF1764 PF08576.5 CDJ64145.1 - 2.4 8.9 27.3 6 7.7 0.2 3.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) Dala_Dala_lig_N PF01820.16 CDJ64145.1 - 7.4 6.9 12.6 24 5.2 3.1 3.6 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus SPX PF03105.14 CDJ64145.1 - 7.6 6.2 24.6 0.023 14.4 2.7 2.7 3 1 0 3 3 3 0 SPX domain UPF0560 PF10577.4 CDJ64145.1 - 8.4 4.5 44.5 0.46 8.6 2.4 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0560 Shadoo PF14999.1 CDJ64146.1 - 0.0046 16.8 0.2 0.0053 16.6 0.1 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective ADP_ribosyl_GH PF03747.9 CDJ64146.1 - 1.8 8.2 8.0 2.1 8.0 5.3 1.3 1 1 0 1 1 1 0 ADP-ribosylglycohydrolase DUF4097 PF13349.1 CDJ64146.1 - 3.8 7.0 6.0 0.54 9.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) Oligomerisation PF02410.10 CDJ64146.1 - 6.9 6.7 8.5 0.14 12.2 0.8 1.8 2 0 0 2 2 2 0 Oligomerisation domain CD20 PF04103.10 CDJ64146.1 - 9.7 6.1 14.5 0.1 12.4 0.8 2.1 1 1 1 2 2 2 0 CD20-like family PAT1 PF09770.4 CDJ64147.1 - 0.00099 17.4 43.7 0.00099 17.4 30.3 3.1 3 0 0 3 3 3 2 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.10 CDJ64147.1 - 0.041 13.0 21.0 0.0049 16.1 8.7 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Herpes_UL87 PF03043.9 CDJ64147.1 - 0.05 11.9 9.2 0.047 12.0 1.9 2.4 1 1 0 2 2 2 0 Herpesvirus UL87 family LMBR1 PF04791.11 CDJ64147.1 - 1.3 7.5 9.4 0.012 14.2 0.6 2.0 3 0 0 3 3 3 0 LMBR1-like membrane protein DUF1053 PF06327.9 CDJ64149.1 - 0.011 16.0 2.6 0.099 12.9 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) MHYT PF03707.11 CDJ64149.1 - 4.8 7.3 7.1 16 5.6 1.1 2.3 1 1 1 2 2 2 0 Bacterial signalling protein N terminal repeat SR-25 PF10500.4 CDJ64150.1 - 0.0092 15.4 7.3 0.0092 15.4 5.1 4.9 3 2 0 3 3 3 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ64150.1 - 2.6 7.3 48.7 0.096 12.0 10.2 3.1 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TBP PF00352.16 CDJ64151.1 - 3.9e-14 51.7 0.0 0.00034 19.9 0.0 3.2 3 0 0 3 3 3 3 Transcription factor TFIID (or TATA-binding protein, TBP) Med15 PF09606.5 CDJ64153.1 - 0.016 13.4 18.8 0.022 12.9 13.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gag_spuma PF03276.9 CDJ64153.1 - 0.64 8.2 16.9 0.92 7.7 11.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Rhabdo_M2 PF04785.7 CDJ64154.1 - 0.0023 16.9 0.2 0.0049 15.9 0.2 1.5 1 0 0 1 1 1 1 Rhabdovirus matrix protein M2 Med15 PF09606.5 CDJ64154.1 - 0.12 10.5 79.0 0.14 10.3 54.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ64154.1 - 0.18 10.0 74.9 0.2 9.8 51.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Baculo_PP31 PF05311.6 CDJ64154.1 - 4.9 6.3 23.3 1 8.5 12.6 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Flavodoxin_1 PF00258.20 CDJ64155.1 - 1.2e-05 25.3 0.0 0.27 11.2 0.0 3.7 2 0 0 2 2 2 2 Flavodoxin TAFH PF07531.9 CDJ64155.1 - 0.33 10.6 4.0 0.72 9.5 2.7 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF DUF4349 PF14257.1 CDJ64156.1 - 0.0073 15.5 4.6 0.0082 15.3 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) CPSF100_C PF13299.1 CDJ64156.1 - 0.074 13.2 0.2 0.082 13.0 0.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DSBA PF01323.15 CDJ64156.1 - 0.074 12.5 3.1 0.093 12.2 2.2 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Peptidase_S8 PF00082.17 CDJ64156.1 - 0.1 11.7 2.0 0.1 11.7 1.4 1.1 1 0 0 1 1 1 0 Subtilase family CDK2AP PF09806.4 CDJ64156.1 - 0.97 9.6 11.0 1.1 9.4 7.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Smac_DIABLO PF09057.5 CDJ64156.1 - 1.4 8.0 8.2 1.6 7.8 5.7 1.1 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases HlyD PF00529.15 CDJ64156.1 - 3.9 6.6 16.2 4.6 6.4 11.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein PepSY_2 PF13670.1 CDJ64156.1 - 8.5 6.3 13.0 16 5.5 9.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain NUDIX PF00293.23 CDJ64157.1 - 0.0015 18.1 10.6 0.052 13.1 7.3 2.5 1 1 0 1 1 1 1 NUDIX domain BTP PF05232.7 CDJ64157.1 - 0.54 10.0 3.3 1.3 8.8 2.3 1.6 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family PAT1 PF09770.4 CDJ64157.1 - 2.8 6.0 27.2 3.5 5.7 18.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA PF00004.24 CDJ64158.1 - 1.4e-18 67.3 0.0 1.4e-18 67.3 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CDJ64158.1 - 0.049 13.5 1.8 0.15 12.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) PAT1 PF09770.4 CDJ64158.1 - 0.16 10.2 44.6 0.22 9.6 30.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_UL87 PF03043.9 CDJ64158.1 - 0.36 9.1 13.0 0.49 8.7 9.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF3395 PF11875.3 CDJ64159.1 - 3e-12 46.3 0.2 5e-12 45.6 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CDJ64160.1 - 6e-12 45.1 0.3 9.6e-12 44.4 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain EF-hand_7 PF13499.1 CDJ64161.1 - 8.1e-06 25.8 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CDJ64161.1 - 8.6e-06 24.8 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CDJ64161.1 - 5e-05 22.3 0.0 7.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CDJ64161.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain DUF605 PF04652.11 CDJ64161.1 - 0.027 13.8 34.1 0.034 13.5 23.7 1.0 1 0 0 1 1 1 0 Vta1 like SPARC_Ca_bdg PF10591.4 CDJ64161.1 - 0.62 10.1 0.1 0.62 10.1 0.1 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TSA PF03249.8 CDJ64161.1 - 0.68 8.3 10.1 1.1 7.6 7.0 1.3 1 0 0 1 1 1 0 Type specific antigen SpoIIIAH PF12685.2 CDJ64161.1 - 6.1 6.2 14.1 14 5.1 9.8 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein Hid1 PF12722.2 CDJ64162.1 - 4.8e-06 24.5 23.5 4.8e-06 24.5 16.3 2.6 2 1 1 3 3 3 1 High-temperature-induced dauer-formation protein Trypan_PARP PF05887.6 CDJ64162.1 - 0.053 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LMBR1 PF04791.11 CDJ64162.1 - 0.22 10.0 10.0 1.3 7.5 0.0 3.0 1 1 1 2 2 2 0 LMBR1-like membrane protein NARP1 PF12569.3 CDJ64162.1 - 1.7 7.2 21.5 3.7 6.1 14.9 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MIP-T3 PF10243.4 CDJ64162.1 - 2.5 6.4 63.5 0.0031 16.0 36.0 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 CDJ64162.1 - 6.9 6.4 21.0 0.74 9.6 11.5 1.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Med15 PF09606.5 CDJ64163.1 - 0.01 14.0 30.6 0.016 13.4 21.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF572 PF04502.8 CDJ64163.1 - 0.34 10.0 10.3 0.5 9.5 7.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ADP_PFK_GK PF04587.10 CDJ64163.1 - 1.9 6.6 4.3 2.8 6.0 3.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DNA_pol_viral_N PF00242.12 CDJ64163.1 - 5.5 5.9 18.0 7.9 5.4 12.5 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2052 PF09747.4 CDJ64164.1 - 0.0013 18.6 26.6 0.063 13.2 3.3 3.5 3 0 0 3 3 3 3 Coiled-coil domain containing protein (DUF2052) FimP PF09766.4 CDJ64164.1 - 0.017 14.2 41.7 0.26 10.3 9.1 3.1 3 0 0 3 3 3 0 Fms-interacting protein Spt20 PF12090.3 CDJ64164.1 - 0.046 13.0 26.8 0.078 12.3 1.1 3.5 3 0 0 3 3 3 0 Spt20 family AAA_23 PF13476.1 CDJ64164.1 - 0.056 13.7 31.8 1.2 9.4 4.0 3.1 3 0 0 3 3 3 0 AAA domain zf-DHHC PF01529.15 CDJ64164.1 - 0.21 10.9 8.3 2.2 7.6 0.3 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase Peptidase_S49_N PF08496.5 CDJ64164.1 - 2.8 7.7 23.1 3.2 7.5 1.2 3.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Med15 PF09606.5 CDJ64164.1 - 3.2 5.8 121.2 1.5 6.9 49.5 2.8 1 1 1 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ64164.1 - 3.5 7.2 46.8 0.39 10.3 6.7 3.5 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) DSHCT PF08148.7 CDJ64165.1 - 0.018 14.2 0.6 0.018 14.2 0.4 2.0 2 0 0 2 2 2 0 DSHCT (NUC185) domain SR-25 PF10500.4 CDJ64165.1 - 0.31 10.4 9.4 0.17 11.3 4.5 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HRDC PF00570.18 CDJ64166.1 - 3e-06 26.8 0.3 4.3e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 HRDC domain Ribosomal_60s PF00428.14 CDJ64167.1 - 0.082 13.3 30.8 0.065 13.6 1.9 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein APC_CDC26 PF10471.4 CDJ64167.1 - 3.6 8.3 8.9 0.29 11.8 2.5 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF89 PF01937.14 CDJ64169.1 - 1.5e-29 102.9 0.0 2.5e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF89 Suf PF05843.9 CDJ64169.1 - 0.73 9.5 6.6 1.2 8.8 4.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ64169.1 - 0.75 9.6 14.2 1.1 9.0 9.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Thioredoxin_4 PF13462.1 CDJ64169.1 - 6.7 6.6 7.9 12 5.8 5.5 1.3 1 0 0 1 1 1 0 Thioredoxin SR-25 PF10500.4 CDJ64170.1 - 8.5 5.7 37.1 1.9 7.9 6.2 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.1 CDJ64172.1 - 0.0015 17.5 14.5 0.0028 16.6 10.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Cwf_Cwc_15 PF04889.7 CDJ64172.1 - 0.0026 17.5 20.5 0.0033 17.1 14.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Trp_oprn_chp PF09534.5 CDJ64172.1 - 0.023 14.2 3.1 0.027 14.0 2.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tetraspannin PF00335.15 CDJ64172.1 - 0.027 13.7 3.0 0.033 13.4 2.1 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4355 PF14265.1 CDJ64172.1 - 0.042 13.7 15.5 0.066 13.1 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) FRQ PF09421.5 CDJ64172.1 - 0.042 11.6 21.5 0.064 11.0 14.9 1.3 1 0 0 1 1 1 0 Frequency clock protein LNP1 PF15419.1 CDJ64172.1 - 0.047 13.7 17.3 0.058 13.4 12.0 1.1 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 IncA PF04156.9 CDJ64172.1 - 0.082 12.4 23.9 0.1 12.1 16.5 1.2 1 0 0 1 1 1 0 IncA protein Zip PF02535.17 CDJ64172.1 - 0.16 10.9 3.0 0.2 10.6 2.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GRP PF07172.6 CDJ64172.1 - 0.18 12.2 5.7 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 Glycine rich protein family DUF3708 PF12501.3 CDJ64172.1 - 0.28 11.0 9.1 0.36 10.6 6.3 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Hid1 PF12722.2 CDJ64172.1 - 0.3 8.7 19.5 0.32 8.6 13.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 CDJ64172.1 - 0.31 10.9 13.6 0.35 10.7 9.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 CDJ64172.1 - 0.43 9.1 15.6 0.49 8.9 10.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1907 PF08925.6 CDJ64172.1 - 0.51 9.3 3.3 0.65 9.0 2.2 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1907) Tir_receptor_N PF07490.6 CDJ64172.1 - 0.57 9.7 6.2 0.58 9.7 4.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Neugrin PF06413.6 CDJ64172.1 - 0.57 9.9 16.2 0.73 9.6 11.3 1.1 1 0 0 1 1 1 0 Neugrin Peptidase_S30 PF01577.11 CDJ64172.1 - 0.73 9.1 13.7 0.89 8.8 9.5 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Neur_chan_memb PF02932.11 CDJ64172.1 - 0.96 9.2 12.4 1.2 8.9 8.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.12 CDJ64172.1 - 0.98 8.1 14.5 1.2 7.8 10.0 1.1 1 0 0 1 1 1 0 Presenilin Vps39_1 PF10366.4 CDJ64172.1 - 1.1 9.3 9.1 0.75 9.8 4.1 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF755 PF05501.6 CDJ64172.1 - 1.1 9.3 46.0 0.031 14.3 23.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) FLO_LFY PF01698.11 CDJ64172.1 - 1.3 7.8 14.8 1.6 7.5 10.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Dicty_REP PF05086.7 CDJ64172.1 - 1.4 6.6 10.4 1.6 6.4 7.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAT1 PF09770.4 CDJ64172.1 - 1.4 7.0 42.3 1.6 6.8 29.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2217 PF10265.4 CDJ64172.1 - 1.4 7.5 15.8 1.7 7.3 10.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SAGA-Tad1 PF12767.2 CDJ64172.1 - 1.5 8.4 27.1 1.9 8.0 18.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SURF6 PF04935.7 CDJ64172.1 - 1.5 8.0 20.3 7.8 5.7 12.5 2.0 2 0 0 2 2 2 0 Surfeit locus protein 6 AAA_23 PF13476.1 CDJ64172.1 - 1.7 8.9 15.9 2.3 8.4 11.0 1.2 1 0 0 1 1 1 0 AAA domain Herpes_UL87 PF03043.9 CDJ64172.1 - 2.2 6.5 9.1 2.4 6.4 6.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family NiFeSe_Hases PF00374.14 CDJ64172.1 - 2.3 6.9 5.5 2.7 6.6 3.8 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase KfrA_N PF11740.3 CDJ64172.1 - 2.4 8.6 28.5 3.4 8.1 19.8 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term FimP PF09766.4 CDJ64172.1 - 2.5 7.0 29.6 0.72 8.8 14.2 2.0 2 0 0 2 2 2 0 Fms-interacting protein Parvo_coat PF00740.13 CDJ64172.1 - 4.3 6.1 20.4 4.9 5.9 14.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 RskA PF10099.4 CDJ64172.1 - 4.7 6.9 17.2 0.91 9.2 0.5 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3276 PF11680.3 CDJ64172.1 - 4.9 6.9 12.5 3.9 7.2 6.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) DUF2681 PF10883.3 CDJ64172.1 - 5.5 7.2 25.6 3.5 7.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DivIC PF04977.10 CDJ64172.1 - 5.9 6.4 27.3 2.7 7.5 2.2 2.2 2 0 0 2 2 2 0 Septum formation initiator SID-1_RNA_chan PF13965.1 CDJ64172.1 - 6.3 4.8 6.2 7.9 4.5 4.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2347 PF09804.4 CDJ64172.1 - 6.3 5.9 11.5 8 5.6 7.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SR-25 PF10500.4 CDJ64172.1 - 9.2 5.6 43.5 0.61 9.5 25.2 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein eIF-3_zeta PF05091.7 CDJ64172.1 - 9.6 4.6 21.1 11 4.4 14.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FliP PF00813.15 CDJ64172.1 - 9.7 5.8 8.3 13 5.3 5.8 1.2 1 0 0 1 1 1 0 FliP family DUF788 PF05620.6 CDJ64172.1 - 9.8 5.9 16.2 8.7 6.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Claudin_2 PF13903.1 CDJ64172.1 - 9.9 5.8 15.6 0.72 9.5 0.6 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CutA1 PF03091.10 CDJ64175.1 - 1.4e-31 108.1 1.1 1.7e-31 107.8 0.8 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF3082 PF11282.3 CDJ64175.1 - 0.0074 16.3 0.5 0.016 15.2 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3082) DUF456 PF04306.8 CDJ64175.1 - 0.069 13.1 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) AsnC_trans_reg PF01037.16 CDJ64175.1 - 0.13 11.9 0.3 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 AsnC family PilX_N PF14341.1 CDJ64175.1 - 0.14 11.8 0.7 0.78 9.4 0.0 2.2 2 0 0 2 2 2 0 PilX N-terminal vATP-synt_E PF01991.13 CDJ64176.1 - 9.3e-59 198.0 1.4 1.1e-58 197.8 1.0 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4239 PF14023.1 CDJ64176.1 - 0.073 12.4 4.9 0.13 11.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF4026 PF13218.1 CDJ64176.1 - 0.31 9.8 1.9 0.37 9.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) CDC37_N PF03234.9 CDJ64176.1 - 0.34 11.2 6.3 0.34 11.1 3.9 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4557 PF15101.1 CDJ64176.1 - 2 8.1 6.6 7.3 6.3 4.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) HrpE PF06188.7 CDJ64176.1 - 7.7 6.2 12.1 24 4.5 8.4 1.7 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E PDCD2_C PF04194.8 CDJ64177.1 - 2.7e-34 118.1 0.1 1e-33 116.2 0.0 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain GvpG PF05120.7 CDJ64177.1 - 0.12 12.2 0.2 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Gas vesicle protein G Kelch_3 PF13415.1 CDJ64178.1 - 6.5e-20 70.7 5.0 7e-07 29.2 0.0 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ64178.1 - 1.3e-16 60.0 1.6 0.00071 19.4 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CDJ64178.1 - 9.3e-14 50.9 8.7 1.3e-05 24.8 0.1 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain HATPase_c_3 PF13589.1 CDJ64178.1 - 8.6e-10 38.4 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CDJ64178.1 - 0.00027 20.6 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_1 PF01344.20 CDJ64178.1 - 0.00056 19.4 0.0 2.3 7.8 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Ribosomal_S3Ae PF01015.13 CDJ64179.1 - 1.5e-80 269.1 0.5 1.8e-80 268.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Lipase_3 PF01764.20 CDJ64181.1 - 8.2e-18 64.3 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CDJ64181.1 - 0.0069 16.2 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDJ64181.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 CDJ64181.1 - 0.048 13.4 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase CUE PF02845.11 CDJ64182.1 - 0.0063 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 CUE domain Kelch_4 PF13418.1 CDJ64183.1 - 5.5e-35 118.9 14.1 1.3e-08 34.4 0.0 6.7 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ64183.1 - 6.9e-29 99.3 0.5 6.4e-06 25.9 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 CDJ64183.1 - 2.3e-28 97.6 10.7 7.8e-07 29.0 0.0 7.9 9 0 0 9 9 9 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CDJ64183.1 - 4.7e-25 86.6 3.8 1.1e-06 28.5 0.2 6.0 4 2 2 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CDJ64183.1 - 5.7e-18 63.8 12.2 1.9e-05 24.2 0.1 6.6 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CDJ64183.1 - 9.3e-16 57.1 3.4 4.4e-05 22.9 0.0 5.5 6 0 0 6 6 6 3 Kelch motif DUF4110 PF13422.1 CDJ64183.1 - 1.5e-14 53.5 0.3 1.5e-14 53.5 0.2 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4110) CDC45 PF02724.9 CDJ64183.1 - 9.7 4.0 13.9 0.33 8.9 4.6 2.0 2 0 0 2 2 2 0 CDC45-like protein MA3 PF02847.12 CDJ64185.1 - 1e-32 112.1 2.7 3e-11 43.0 0.0 3.1 3 0 0 3 3 3 3 MA3 domain B56 PF01603.15 CDJ64185.1 - 0.1 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PARP PF00644.15 CDJ64186.1 - 0.0046 16.4 0.0 0.015 14.7 0.0 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SH3_3 PF08239.6 CDJ64187.1 - 0.0042 17.2 0.0 3.6 7.8 0.0 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain DUF4120 PF13496.1 CDJ64187.1 - 0.11 12.4 0.0 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) Pex16 PF08610.5 CDJ64188.1 - 7.3e-20 71.2 0.8 1.9e-15 56.6 0.1 2.3 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) Sec7 PF01369.15 CDJ64189.1 - 1.1e-62 211.0 0.0 1.8e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CDJ64189.1 - 5.5e-12 45.4 0.1 2e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal ThylakoidFormat PF11264.3 CDJ64190.1 - 1.1 8.7 4.0 0.33 10.5 0.2 1.9 2 0 0 2 2 2 0 Thylakoid formation protein PapD_N PF00345.15 CDJ64191.1 - 0.094 12.5 0.1 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain SARS_lipid_bind PF09399.5 CDJ64192.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.8 1 1 0 1 1 1 0 SARS lipid binding protein PAZ PF02170.17 CDJ64193.1 - 3.7e-08 32.7 0.1 3.9e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 PAZ domain Piwi PF02171.12 CDJ64193.1 - 4.9e-08 32.2 0.0 6.8e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Piwi domain IFR3_antag PF14754.1 CDJ64193.1 - 0.12 11.3 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 Papain-like auto-proteinase WGG PF10273.4 CDJ64194.1 - 2.7e-23 81.8 0.5 4.7e-23 81.0 0.4 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Tautomerase_2 PF14552.1 CDJ64194.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme 7TM_transglut PF14402.1 CDJ64196.1 - 0.02 13.8 0.1 0.031 13.2 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Presenilin PF01080.12 CDJ64196.1 - 3.4 6.4 7.6 1.5 7.5 0.1 2.1 2 0 0 2 2 2 0 Presenilin DUF4512 PF14975.1 CDJ64196.1 - 4.1 8.3 5.2 20 6.1 1.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4512) TPR_11 PF13414.1 CDJ64197.1 - 4e-13 48.7 12.9 2.5e-10 39.8 2.7 3.3 2 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CDJ64197.1 - 4.2e-12 45.0 12.2 0.00085 19.0 0.2 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ64197.1 - 2.9e-10 39.2 7.3 0.01 15.4 0.5 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ64197.1 - 2.5e-07 29.9 6.4 0.09 12.5 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ64197.1 - 2.6e-07 31.1 4.4 0.012 16.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ64197.1 - 4.6e-06 26.4 6.1 0.29 11.1 0.5 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ64197.1 - 0.0009 19.6 5.9 2.1 9.2 0.1 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 CDJ64197.1 - 0.0017 18.1 0.2 0.0017 18.1 0.1 3.1 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 CDJ64197.1 - 0.0033 17.7 10.1 5 7.8 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ64197.1 - 0.0038 16.9 0.8 3.7 7.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ64197.1 - 0.0082 16.4 6.0 0.93 9.8 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.4 CDJ64197.1 - 0.0095 14.5 1.2 0.015 13.9 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Uds1 PF15456.1 CDJ64197.1 - 0.044 13.7 0.2 0.044 13.7 0.2 1.8 2 0 0 2 2 2 0 Up-regulated During Septation zf-C4pol PF14260.1 CDJ64197.1 - 0.055 13.4 0.6 0.055 13.4 0.4 2.0 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF2508 PF10704.4 CDJ64197.1 - 0.081 13.1 0.1 0.081 13.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) TPR_17 PF13431.1 CDJ64197.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CDJ64197.1 - 0.17 11.8 0.7 11 6.0 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_27 PF13514.1 CDJ64197.1 - 0.6 7.7 6.2 0.7 7.5 4.3 1.1 1 0 0 1 1 1 0 AAA domain Acyl-CoA_ox_N PF14749.1 CDJ64197.1 - 0.65 10.2 3.6 1.2 9.4 0.1 2.7 2 1 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal DOG1 PF14144.1 CDJ64197.1 - 0.75 9.8 3.6 0.35 10.9 0.3 2.1 2 1 0 2 2 2 0 Seed dormancy control Tat PF00539.13 CDJ64197.1 - 0.83 9.3 4.5 0.8 9.3 1.1 2.1 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) BTAD PF03704.12 CDJ64197.1 - 1.5 9.1 8.1 0.94 9.7 3.5 2.3 1 1 2 3 3 3 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 CDJ64197.1 - 5.1 7.8 8.0 6.5 7.5 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Tir_receptor_N PF07490.6 CDJ64199.1 - 0.0023 17.5 1.4 0.0023 17.5 1.0 2.7 3 0 0 3 3 3 1 Translocated intimin receptor (Tir) N-terminus FimP PF09766.4 CDJ64199.1 - 0.0089 15.1 0.4 0.0089 15.1 0.3 4.4 4 1 0 4 4 4 1 Fms-interacting protein Plasmodium_Vir PF05795.6 CDJ64199.1 - 0.89 8.6 2.8 2 7.5 0.5 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF3628 PF12300.3 CDJ64200.1 - 0.62 10.0 5.2 0.67 9.9 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Stm1_N PF09598.5 CDJ64200.1 - 0.7 10.6 5.2 0.18 12.4 1.6 1.5 2 0 0 2 2 2 0 Stm1 Chorion_2 PF03964.10 CDJ64200.1 - 2.8 8.5 18.7 0.17 12.4 5.1 2.1 1 1 1 2 2 2 0 Chorion family 2 DnaJ PF00226.26 CDJ64202.1 - 4.8e-18 64.6 0.5 1.4e-17 63.1 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain DUF566 PF04484.7 CDJ64202.1 - 0.07 12.6 10.5 0.086 12.3 7.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SR-25 PF10500.4 CDJ64202.1 - 0.082 12.3 7.4 0.13 11.7 5.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CDJ64202.1 - 2.4 6.3 5.9 3 6.0 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 CDJ64203.1 - 1.4e-05 24.8 3.9 1.4e-05 24.8 2.7 2.1 2 0 0 2 2 2 1 IncA protein SARG PF15385.1 CDJ64203.1 - 0.11 11.8 29.7 0.16 11.3 20.6 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Zip PF02535.17 CDJ64203.1 - 0.21 10.5 7.1 0.29 10.0 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter XRCC4 PF06632.7 CDJ64203.1 - 0.56 9.0 15.8 0.83 8.4 10.9 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 FAM176 PF14851.1 CDJ64203.1 - 0.7 9.5 7.6 6.8 6.3 3.1 2.1 2 0 0 2 2 2 0 FAM176 family RAP1 PF07218.6 CDJ64203.1 - 2.9 5.8 4.8 2.8 5.9 3.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) eIF_4EBP PF05456.6 CDJ64203.1 - 3.3 7.4 13.7 13 5.4 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FimP PF09766.4 CDJ64203.1 - 3.7 6.5 25.8 0.23 10.5 10.6 2.0 2 0 0 2 2 2 0 Fms-interacting protein PBP1_TM PF14812.1 CDJ64203.1 - 3.8 7.8 7.0 21 5.5 3.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF605 PF04652.11 CDJ64203.1 - 5.5 6.2 36.0 7.1 5.9 24.9 1.0 1 0 0 1 1 1 0 Vta1 like RNA_pol_Rpc4 PF05132.9 CDJ64203.1 - 10 6.1 13.7 3.6 7.5 4.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF92 PF01940.11 CDJ64204.1 - 0.92 8.6 6.1 0.13 11.3 0.2 1.9 1 1 1 2 2 2 0 Integral membrane protein DUF92 MSP1_C PF07462.6 CDJ64204.1 - 1.6 7.0 6.3 1.7 6.9 4.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF572 PF04502.8 CDJ64204.1 - 4 6.5 19.9 4.5 6.3 13.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pol_alpha_B_N PF08418.5 CDJ64204.1 - 4.2 6.8 21.1 4.7 6.6 14.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SR-25 PF10500.4 CDJ64204.1 - 4.4 6.7 33.7 35 3.7 4.8 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein TATR PF03430.8 CDJ64204.1 - 6.5 5.2 15.1 7 5.1 10.5 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Peptidase_M50 PF02163.17 CDJ64205.1 - 0.0025 16.8 0.0 0.0089 15.0 0.0 1.9 1 0 0 1 1 1 1 Peptidase family M50 Spt20 PF12090.3 CDJ64206.1 - 0.0032 16.8 4.2 0.0032 16.8 2.9 2.1 2 0 0 2 2 2 1 Spt20 family NTP_transf_2 PF01909.18 CDJ64206.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase domain PAT1 PF09770.4 CDJ64206.1 - 0.94 7.6 38.3 1.5 6.9 26.5 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1631 PF07793.6 CDJ64208.1 - 0.00013 20.2 7.6 0.00013 20.2 5.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1631) IncA PF04156.9 CDJ64208.1 - 0.15 11.6 24.7 1.1 8.8 10.2 2.3 2 0 0 2 2 2 0 IncA protein DUF3449 PF11931.3 CDJ64208.1 - 2.8 7.4 0.0 2.8 7.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3449) AAA_23 PF13476.1 CDJ64208.1 - 4.2 7.6 14.6 2.1 8.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain RAB3GAP2_N PF14655.1 CDJ64208.1 - 6.9 5.5 19.8 4.1 6.2 3.2 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4557 PF15101.1 CDJ64208.1 - 9.2 6.0 24.4 3.2 7.5 4.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Sec7 PF01369.15 CDJ64210.1 - 9.7e-57 191.7 0.0 2.1e-56 190.6 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain DUF1981 PF09324.5 CDJ64210.1 - 3.2e-08 32.9 0.0 1.3e-07 31.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) UCR_UQCRX_QCR9 PF05365.7 CDJ64211.1 - 5.9e-10 38.6 3.2 8.5e-10 38.1 2.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2593 PF10767.4 CDJ64211.1 - 0.05 13.3 0.7 0.051 13.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) SNF2_N PF00176.18 CDJ64213.1 - 7.7e-58 195.6 0.0 1.3e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.24 CDJ64213.1 - 1.7e-21 75.6 83.3 9.2e-11 41.2 4.8 7.1 7 1 0 7 7 7 4 PHD-finger Helicase_C PF00271.26 CDJ64213.1 - 6.9e-12 45.0 0.1 4.4e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDJ64213.1 - 4.9e-06 26.5 0.0 1.6e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CDJ64213.1 - 1.1e-05 24.9 0.0 5.3e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase PHD_2 PF13831.1 CDJ64213.1 - 0.00027 20.1 1.5 0.00027 20.1 1.1 6.7 7 0 0 7 7 7 1 PHD-finger Prok-RING_1 PF14446.1 CDJ64213.1 - 0.0015 18.2 2.5 0.0015 18.2 1.7 6.9 7 1 1 8 8 8 2 Prokaryotic RING finger family 1 AAA_14 PF13173.1 CDJ64213.1 - 0.0027 17.6 0.0 0.0087 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain C1_1 PF00130.17 CDJ64213.1 - 0.0045 16.6 1.5 0.0045 16.6 1.0 7.6 6 1 1 7 7 7 4 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 CDJ64213.1 - 0.0047 16.2 1.8 0.0047 16.2 1.2 7.3 5 2 2 7 7 7 2 PHD/FYVE-zinc-finger like domain CAF-1_p150 PF11600.3 CDJ64214.1 - 2.5 7.4 24.9 5.4 6.3 17.3 1.5 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Trichoplein PF13868.1 CDJ64214.1 - 6 5.1 38.5 0.68 8.2 20.4 2.3 2 1 0 2 2 2 0 Tumour suppressor, Mitostatin DUF390 PF04094.9 CDJ64215.1 - 0.28 9.1 3.4 0.3 9.1 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) CAF-1_p150 PF11600.3 CDJ64215.1 - 0.42 9.9 20.6 0.45 9.8 14.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PTPlike_phytase PF14566.1 CDJ64215.1 - 2.8 7.9 7.2 3.8 7.5 5.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DDRGK PF09756.4 CDJ64215.1 - 5.6 6.3 20.3 6.8 6.0 14.1 1.1 1 0 0 1 1 1 0 DDRGK domain DUF1168 PF06658.7 CDJ64215.1 - 5.7 6.4 18.7 6.7 6.2 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SET PF00856.23 CDJ64216.1 - 1.5e-10 41.6 2.5 1.1e-09 38.8 0.0 3.6 3 2 0 3 3 3 1 SET domain PM0188 PF11477.3 CDJ64216.1 - 0.38 9.5 0.0 0.62 8.8 0.0 1.2 1 0 0 1 1 1 0 Sialyltransferase PMO188 Arm PF00514.18 CDJ64217.1 - 1.6e-08 34.0 8.1 0.064 13.0 0.0 6.0 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDJ64217.1 - 7.5e-07 29.3 4.3 0.00035 20.8 0.0 4.1 3 2 1 4 4 4 2 HEAT repeats V-ATPase_H_C PF11698.3 CDJ64217.1 - 3.5e-05 23.7 0.1 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.17 CDJ64217.1 - 0.0029 17.5 8.4 10 6.4 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat SPO22 PF08631.5 CDJ64217.1 - 0.0058 15.7 0.1 0.83 8.6 0.0 2.3 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like HEAT_EZ PF13513.1 CDJ64217.1 - 0.46 11.0 3.5 5.1 7.7 0.0 4.3 6 0 0 6 6 6 0 HEAT-like repeat Tim17 PF02466.14 CDJ64219.1 - 3.3e-30 104.7 3.7 4.6e-30 104.3 2.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LigB PF02900.13 CDJ64220.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF1823 PF08853.6 CDJ64221.1 - 0.75 9.5 3.2 0.99 9.1 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1823) UvrD-helicase PF00580.16 CDJ64222.1 - 7.3e-47 160.1 0.1 3.6e-42 144.7 0.0 2.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 CDJ64222.1 - 2.1e-38 132.6 0.9 8.1e-19 68.2 0.0 4.1 4 0 0 4 4 4 3 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CDJ64222.1 - 1.1e-10 41.0 1.6 4.4e-10 39.1 0.1 2.9 3 0 0 3 3 3 1 Part of AAA domain UvrD_C_2 PF13538.1 CDJ64222.1 - 1.8e-07 31.2 6.2 0.00013 22.0 0.0 3.3 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain Evr1_Alr PF04777.8 CDJ64223.1 - 8e-22 76.9 0.0 9.3e-22 76.7 0.0 1.0 1 0 0 1 1 1 1 Erv1 / Alr family DHO_dh PF01180.16 CDJ64224.1 - 4.6e-103 344.2 0.0 5.3e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CDJ64224.1 - 0.00048 19.0 0.6 0.0013 17.6 0.3 1.9 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CDJ64224.1 - 0.032 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase PcrB PF01884.12 CDJ64224.1 - 0.057 12.6 0.4 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 PcrB family IMPDH PF00478.20 CDJ64224.1 - 0.075 11.9 0.2 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Fusion_gly PF00523.13 CDJ64226.1 - 0.018 13.0 0.1 0.036 12.1 0.1 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 PRKCSH PF07915.8 CDJ64227.1 - 8.2e-13 48.9 0.0 1.1e-05 26.1 0.0 3.0 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein YccV-like PF08755.6 CDJ64227.1 - 1.3e-10 41.0 0.1 2.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH_1 PF13015.1 CDJ64227.1 - 6.7e-05 22.3 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein MNNL PF07657.8 CDJ64227.1 - 0.047 13.6 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 N terminus of Notch ligand ABC_membrane PF00664.18 CDJ64228.1 - 0.38 10.1 2.8 1.9 7.8 0.1 2.4 2 1 0 2 2 2 0 ABC transporter transmembrane region Spore_III_AF PF09581.5 CDJ64228.1 - 2.4 7.9 5.8 14 5.4 0.8 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) UCH PF00443.24 CDJ64229.1 - 1.3e-38 132.6 0.1 2.8e-37 128.3 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDJ64229.1 - 8.4e-06 25.4 0.0 0.0018 17.7 0.0 3.7 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase ABC_tran PF00005.22 CDJ64230.1 - 8.1e-45 152.4 0.8 3.9e-22 79.0 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CDJ64230.1 - 1.2e-21 78.0 2.6 1.1e-06 28.8 0.1 5.0 4 1 1 5 5 5 4 AAA domain ABC_tran_2 PF12848.2 CDJ64230.1 - 5.2e-17 61.4 1.8 5.2e-17 61.4 1.3 3.2 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 CDJ64230.1 - 4.8e-09 35.7 5.1 0.00032 19.9 0.0 4.2 3 2 1 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CDJ64230.1 - 4.1e-08 32.7 2.6 0.095 11.7 0.0 4.9 4 1 1 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 CDJ64230.1 - 1.5e-07 32.2 0.8 0.022 15.5 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDJ64230.1 - 2e-07 30.3 0.2 0.018 14.5 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CDJ64230.1 - 1.9e-06 27.8 0.1 0.029 14.3 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CDJ64230.1 - 2e-06 27.0 0.0 0.041 13.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CDJ64230.1 - 7.5e-06 26.4 0.0 0.17 12.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 CDJ64230.1 - 1.2e-05 25.2 0.4 0.033 14.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 CDJ64230.1 - 1.3e-05 25.0 0.3 0.12 12.2 0.0 3.0 3 0 0 3 3 2 2 Dynamin family AAA_18 PF13238.1 CDJ64230.1 - 0.00017 21.8 1.4 0.16 12.2 0.0 4.1 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.13 CDJ64230.1 - 0.00019 20.9 1.0 1.2 8.5 0.0 3.4 2 1 1 3 3 3 2 FtsK/SpoIIIE family AAA_22 PF13401.1 CDJ64230.1 - 0.00029 20.9 4.0 0.32 11.1 0.2 3.9 4 1 0 4 4 3 2 AAA domain AAA_10 PF12846.2 CDJ64230.1 - 0.00044 19.7 0.0 0.037 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 CDJ64230.1 - 0.00046 19.8 0.1 1.1 8.8 0.0 3.0 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.1 CDJ64230.1 - 0.0023 17.8 0.2 1.9 8.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain MobB PF03205.9 CDJ64230.1 - 0.0054 16.4 0.0 0.7 9.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CDJ64230.1 - 0.0072 16.3 6.0 0.12 12.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 CDJ64230.1 - 0.011 15.9 0.0 3.7 7.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 CDJ64230.1 - 0.016 14.6 0.0 2.2 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 CDJ64230.1 - 0.021 14.0 0.1 0.65 9.2 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family ArgK PF03308.11 CDJ64230.1 - 0.022 13.5 0.0 3.7 6.2 0.0 2.5 2 0 0 2 2 2 0 ArgK protein SbcCD_C PF13558.1 CDJ64230.1 - 0.025 14.4 0.1 1.9 8.4 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 CDJ64230.1 - 0.041 13.5 0.0 17 5.0 0.0 3.3 3 0 0 3 3 3 0 NTPase Septin PF00735.13 CDJ64230.1 - 0.046 12.7 0.1 9.1 5.2 0.0 2.7 2 1 1 3 3 3 0 Septin DUF87 PF01935.12 CDJ64230.1 - 0.077 12.8 2.9 1.6 8.5 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_23 PF13476.1 CDJ64230.1 - 0.083 13.2 0.2 0.083 13.2 0.2 4.8 3 2 1 5 5 5 0 AAA domain Seryl_tRNA_N PF02403.17 CDJ64230.1 - 0.095 12.7 0.0 0.095 12.7 0.0 2.8 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain G-alpha PF00503.15 CDJ64230.1 - 0.5 9.0 5.8 0.89 8.1 0.0 2.8 2 1 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 CDJ64230.1 - 0.52 10.2 7.2 5.3 6.9 0.2 3.6 2 2 0 2 2 2 0 AAA ATPase domain S4 PF01479.20 CDJ64231.1 - 0.00022 20.5 0.0 0.00039 19.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.17 CDJ64231.1 - 0.0021 17.8 0.0 0.0034 17.2 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase ubiquitin PF00240.18 CDJ64232.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family zf-met2 PF12907.2 CDJ64233.1 - 1.4e-17 63.3 7.4 1.8e-17 62.9 5.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 CDJ64233.1 - 2.4e-07 31.3 7.5 3.8e-07 30.7 5.2 1.3 1 0 0 1 1 1 1 4F5 protein family zf-H2C2_5 PF13909.1 CDJ64233.1 - 0.039 14.2 1.6 0.083 13.1 1.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Cucumo_coat PF00760.13 CDJ64233.1 - 0.14 11.0 0.4 0.15 10.9 0.3 1.0 1 0 0 1 1 1 0 Cucumovirus coat protein zf-BED PF02892.10 CDJ64233.1 - 0.14 11.9 1.4 0.25 11.1 1.0 1.5 1 1 0 1 1 1 0 BED zinc finger zf-DBF PF07535.7 CDJ64233.1 - 0.32 10.7 2.9 1.5 8.5 2.0 2.0 1 1 0 1 1 1 0 DBF zinc finger DUF1049 PF06305.6 CDJ64234.1 - 0.055 12.9 1.4 0.1 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Gram_pos_anchor PF00746.16 CDJ64234.1 - 0.098 12.4 0.8 0.32 10.8 0.5 1.9 1 0 0 1 1 1 0 Gram positive anchor Podoplanin PF05808.6 CDJ64234.1 - 0.98 8.9 4.5 0.47 9.9 0.3 2.2 2 0 0 2 2 2 0 Podoplanin Patched PF02460.13 CDJ64235.1 - 7.5e-87 292.0 0.0 7.2e-86 288.8 0.0 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 CDJ64235.1 - 1.9e-29 102.1 25.0 9.4e-28 96.6 1.5 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 CDJ64235.1 - 5 4.3 30.2 0.11 9.8 15.4 1.9 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family MtN3_slv PF03083.11 CDJ64236.1 - 3.1e-13 49.4 2.0 3.8e-08 33.0 0.2 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Protocadherin PF08374.6 CDJ64236.1 - 0.013 15.1 0.2 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Protocadherin Suf PF05843.9 CDJ64236.1 - 0.031 14.0 1.2 0.037 13.7 0.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2215 PF10225.4 CDJ64236.1 - 0.88 8.9 3.7 1.6 8.0 2.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) zf-LSD1 PF06943.7 CDJ64236.1 - 3.7 7.2 8.0 0.65 9.6 2.5 2.2 2 0 0 2 2 2 0 LSD1 zinc finger Med15 PF09606.5 CDJ64237.1 - 0.38 8.8 26.6 0.46 8.6 18.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF429 PF04250.8 CDJ64237.1 - 2.8 7.1 4.8 0.99 8.6 1.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF429) PAT1 PF09770.4 CDJ64237.1 - 4.1 5.5 23.7 4.7 5.3 16.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ64240.1 - 0.00083 19.7 11.2 0.00083 19.7 7.8 2.4 2 0 0 2 2 2 1 AAA domain SseC PF04888.7 CDJ64240.1 - 0.0013 18.1 31.0 0.0013 18.1 21.5 2.5 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family Raftlin PF15250.1 CDJ64240.1 - 0.0043 15.6 23.0 0.026 13.0 12.5 2.1 2 0 0 2 2 2 2 Raftlin Hid1 PF12722.2 CDJ64240.1 - 0.064 10.9 21.5 0.028 12.1 12.6 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Presenilin PF01080.12 CDJ64240.1 - 0.55 8.9 20.2 5 5.8 12.0 2.4 2 0 0 2 2 2 0 Presenilin SOBP PF15279.1 CDJ64240.1 - 1.2 9.4 25.0 2.7 8.2 13.9 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein MSP1_C PF07462.6 CDJ64240.1 - 2.1 6.6 14.7 4 5.7 10.2 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SAGA-Tad1 PF12767.2 CDJ64240.1 - 2.4 7.7 31.5 4.2 6.9 16.2 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit OMP_b-brl PF13505.1 CDJ64240.1 - 7 6.5 10.3 20 5.0 7.1 1.7 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Zip PF02535.17 CDJ64241.1 - 0.014 14.3 4.6 0.014 14.3 3.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CDJ64241.1 - 0.026 12.5 8.4 0.026 12.5 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.5 CDJ64241.1 - 0.027 14.2 12.8 0.029 14.1 8.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Gag_spuma PF03276.9 CDJ64241.1 - 0.037 12.3 29.8 0.043 12.1 20.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DDHD PF02862.12 CDJ64241.1 - 0.038 13.7 12.6 0.042 13.6 8.7 1.0 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDJ64241.1 - 0.047 12.4 12.0 0.053 12.2 8.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) AIF_C PF14721.1 CDJ64241.1 - 0.053 13.7 10.7 0.063 13.5 7.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_U57 PF05582.7 CDJ64241.1 - 0.054 12.4 11.5 0.065 12.1 7.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF2360 PF10152.4 CDJ64241.1 - 0.066 13.4 12.6 0.075 13.3 8.8 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Baculo_PP31 PF05311.6 CDJ64241.1 - 0.07 12.3 13.0 0.077 12.2 9.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RIC3 PF15361.1 CDJ64241.1 - 0.081 13.1 13.8 0.097 12.9 9.5 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 OATP PF03137.15 CDJ64241.1 - 0.094 10.7 10.7 0.091 10.7 7.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2201_N PF13203.1 CDJ64241.1 - 0.097 11.8 13.8 0.11 11.7 9.5 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Peroxin-13_N PF04088.8 CDJ64241.1 - 0.1 12.5 7.2 0.14 12.0 5.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FAM60A PF15396.1 CDJ64241.1 - 0.11 12.2 8.7 0.11 12.2 6.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Raftlin PF15250.1 CDJ64241.1 - 0.11 11.0 12.8 0.1 11.0 8.9 1.0 1 0 0 1 1 1 0 Raftlin LpxB PF02684.10 CDJ64241.1 - 0.12 10.9 10.9 0.14 10.7 7.6 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DUF4011 PF13195.1 CDJ64241.1 - 0.14 12.1 10.7 0.18 11.7 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Tim54 PF11711.3 CDJ64241.1 - 0.15 10.6 8.0 0.16 10.4 5.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 CDJ64241.1 - 0.17 11.3 20.9 0.18 11.2 14.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PAT1 PF09770.4 CDJ64241.1 - 0.18 10.0 40.3 0.19 9.9 28.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FLO_LFY PF01698.11 CDJ64241.1 - 0.18 10.6 12.4 0.19 10.5 8.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein 2OG-FeII_Oxy_5 PF13759.1 CDJ64241.1 - 0.19 12.0 5.4 0.25 11.6 3.8 1.2 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Paf1 PF03985.8 CDJ64241.1 - 0.19 10.4 16.9 0.19 10.4 11.7 1.0 1 0 0 1 1 1 0 Paf1 RP-C_C PF11800.3 CDJ64241.1 - 0.19 11.3 13.1 0.21 11.2 9.1 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region SpoVR PF04293.8 CDJ64241.1 - 0.23 9.7 13.4 0.23 9.7 9.3 1.1 1 0 0 1 1 1 0 SpoVR like protein CPSF100_C PF13299.1 CDJ64241.1 - 0.24 11.5 12.2 0.26 11.4 8.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Dala_Dala_lig_N PF01820.16 CDJ64241.1 - 0.24 11.7 7.7 0.29 11.4 5.3 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Rtf2 PF04641.7 CDJ64241.1 - 0.24 10.5 12.5 0.23 10.6 8.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1764 PF08576.5 CDJ64241.1 - 0.28 11.9 16.0 0.36 11.6 11.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pex14_N PF04695.8 CDJ64241.1 - 0.29 11.1 26.4 0.37 10.8 18.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Folate_carrier PF01770.13 CDJ64241.1 - 0.36 9.3 7.6 0.32 9.4 5.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier Ycf1 PF05758.7 CDJ64241.1 - 0.36 8.4 13.4 0.37 8.4 9.3 1.1 1 0 0 1 1 1 0 Ycf1 Draxin PF15550.1 CDJ64241.1 - 0.38 10.3 11.4 0.41 10.2 7.9 1.0 1 0 0 1 1 1 0 Draxin DUF4557 PF15101.1 CDJ64241.1 - 0.41 10.4 27.7 0.43 10.3 19.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) HGTP_anticodon2 PF12745.2 CDJ64241.1 - 0.42 9.7 12.2 0.48 9.5 8.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Shisa PF13908.1 CDJ64241.1 - 0.49 10.5 14.4 0.51 10.4 10.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PBP1_TM PF14812.1 CDJ64241.1 - 0.49 10.7 6.6 0.68 10.2 4.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SprA-related PF12118.3 CDJ64241.1 - 0.51 9.6 41.5 0.61 9.3 28.8 1.1 1 0 0 1 1 1 0 SprA-related family GAGA_bind PF06217.7 CDJ64241.1 - 0.51 10.2 14.0 0.56 10.1 9.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CDJ64241.1 - 0.54 10.0 14.3 0.64 9.8 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.8 CDJ64241.1 - 0.58 9.6 16.8 0.69 9.3 11.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Herpes_DNAp_acc PF04929.7 CDJ64241.1 - 0.65 8.8 12.3 0.77 8.6 8.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SpoIIP PF07454.6 CDJ64241.1 - 0.67 9.0 12.8 0.72 8.9 8.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hom_end_hint PF05203.11 CDJ64241.1 - 0.75 9.4 7.5 0.9 9.2 5.2 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint DUF853 PF05872.7 CDJ64241.1 - 0.76 8.0 12.7 0.82 7.9 8.8 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AUX_IAA PF02309.11 CDJ64241.1 - 0.76 9.4 11.8 0.8 9.4 8.2 1.1 1 0 0 1 1 1 0 AUX/IAA family SeqA PF03925.8 CDJ64241.1 - 0.78 9.4 13.9 0.91 9.1 9.6 1.2 1 0 0 1 1 1 0 SeqA protein MDFI PF15316.1 CDJ64241.1 - 0.8 9.6 7.6 0.86 9.5 5.3 1.1 1 0 0 1 1 1 0 MyoD family inhibitor NARP1 PF12569.3 CDJ64241.1 - 0.81 8.3 15.4 0.94 8.1 10.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.11 CDJ64241.1 - 0.88 9.4 8.5 0.94 9.3 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 CDJ64241.1 - 0.93 7.5 8.5 1 7.4 5.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3260 PF11658.3 CDJ64241.1 - 0.96 7.5 13.0 0.98 7.4 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Presenilin PF01080.12 CDJ64241.1 - 0.99 8.1 7.5 0.99 8.1 5.2 1.1 1 0 0 1 1 1 0 Presenilin MSA-2c PF12238.3 CDJ64241.1 - 1.1 8.8 10.7 1.2 8.7 7.4 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF4512 PF14975.1 CDJ64241.1 - 1.4 9.7 8.0 1.8 9.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) PcfK PF14058.1 CDJ64241.1 - 1.5 8.9 20.0 1.8 8.7 13.9 1.1 1 0 0 1 1 1 0 PcfK-like protein TFIIA PF03153.8 CDJ64241.1 - 1.5 8.6 31.1 1.7 8.4 21.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.10 CDJ64241.1 - 1.6 8.7 8.9 1.8 8.5 6.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Hid1 PF12722.2 CDJ64241.1 - 1.7 6.1 17.0 1.8 6.1 11.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Bul1_N PF04425.7 CDJ64241.1 - 1.8 7.0 14.2 1.9 6.9 9.8 1.0 1 0 0 1 1 1 0 Bul1 N terminus HCO3_cotransp PF00955.16 CDJ64241.1 - 1.9 7.0 5.2 2 6.9 3.6 1.0 1 0 0 1 1 1 0 HCO3- transporter family Dynamin_N PF00350.18 CDJ64241.1 - 2 8.1 8.8 2.2 8.0 6.1 1.1 1 0 0 1 1 1 0 Dynamin family Het-C PF07217.6 CDJ64241.1 - 2.2 6.3 11.5 2.4 6.2 8.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C F-protein PF00469.15 CDJ64241.1 - 2.3 7.5 13.3 2.6 7.3 9.2 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Gti1_Pac2 PF09729.4 CDJ64241.1 - 2.3 8.0 11.9 2.9 7.7 8.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family YABBY PF04690.8 CDJ64241.1 - 2.6 8.2 10.8 3.1 8.0 7.5 1.1 1 0 0 1 1 1 0 YABBY protein Pneumo_phosprot PF02478.11 CDJ64241.1 - 2.6 7.4 5.3 2.8 7.4 3.6 1.0 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Cellulose_synt PF03552.9 CDJ64241.1 - 2.6 6.2 6.9 2.9 6.0 4.8 1.0 1 0 0 1 1 1 0 Cellulose synthase FYDLN_acid PF09538.5 CDJ64241.1 - 2.8 8.5 8.3 3.5 8.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Spc7_N PF15402.1 CDJ64241.1 - 2.8 5.8 22.4 3 5.7 15.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 EIIBC-GUT_N PF03612.9 CDJ64241.1 - 2.8 7.5 14.2 3.7 7.1 9.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Mem_trans PF03547.13 CDJ64241.1 - 2.8 6.1 6.6 2.6 6.2 4.6 1.1 1 0 0 1 1 1 0 Membrane transport protein Bestrophin PF01062.16 CDJ64241.1 - 3 6.7 9.3 3.3 6.5 6.5 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Sec62 PF03839.11 CDJ64241.1 - 3.3 7.0 11.5 3.5 6.9 7.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Plasmodium_Vir PF05795.6 CDJ64241.1 - 3.5 6.7 5.5 3.8 6.6 3.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1980 PF09323.5 CDJ64241.1 - 4.3 7.0 14.2 4.7 6.9 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) GOLD_2 PF13897.1 CDJ64241.1 - 4.4 7.5 7.8 6 7.1 5.4 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF4220 PF13968.1 CDJ64241.1 - 4.6 6.2 7.4 5 6.1 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CobT PF06213.7 CDJ64241.1 - 4.6 6.2 15.1 5.8 5.9 10.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CD20 PF04103.10 CDJ64241.1 - 4.8 7.0 7.7 7 6.5 5.3 1.3 1 0 0 1 1 1 0 CD20-like family FAM176 PF14851.1 CDJ64241.1 - 4.9 6.8 9.4 6 6.5 6.5 1.2 1 0 0 1 1 1 0 FAM176 family DUF1800 PF08811.6 CDJ64241.1 - 5 5.9 20.2 4.9 5.9 14.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) EPL1 PF10513.4 CDJ64241.1 - 5.6 7.1 18.2 6.6 6.9 12.6 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like G-alpha PF00503.15 CDJ64241.1 - 5.7 5.5 16.5 7.3 5.1 11.5 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DHHW PF14286.1 CDJ64241.1 - 5.7 6.1 13.4 6.5 5.9 9.3 1.1 1 0 0 1 1 1 0 DHHW protein R_equi_Vir PF05526.6 CDJ64241.1 - 5.8 6.5 6.9 7 6.2 4.8 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Med15 PF09606.5 CDJ64241.1 - 6.1 4.9 58.5 6.4 4.8 40.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TraH_2 PF06871.6 CDJ64241.1 - 6.5 6.1 9.4 8.3 5.7 6.5 1.1 1 0 0 1 1 1 0 TraH_2 DUF2215 PF10225.4 CDJ64241.1 - 6.6 6.0 9.5 7.8 5.8 6.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Pex16 PF08610.5 CDJ64241.1 - 6.8 5.5 15.8 8.4 5.2 11.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) CRF1 PF10380.4 CDJ64241.1 - 7.2 6.9 11.4 9 6.6 7.9 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 Pal1 PF08316.6 CDJ64241.1 - 7.4 7.0 9.8 9.1 6.7 6.8 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Ndc1_Nup PF09531.5 CDJ64241.1 - 7.6 4.8 15.1 7.9 4.7 10.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bud13 PF09736.4 CDJ64241.1 - 8.2 6.6 24.3 11 6.3 16.8 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF1266 PF06889.6 CDJ64241.1 - 9.4 5.9 11.9 13 5.5 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) WD40 PF00400.27 CDJ64242.1 - 1.2e-07 31.3 0.1 0.02 14.7 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF4455 PF14643.1 CDJ64244.1 - 0.0097 14.5 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) CDC45 PF02724.9 CDJ64244.1 - 0.16 9.9 2.8 0.43 8.5 1.9 1.8 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 CDJ64245.1 - 5.9e-20 71.5 28.7 9.2e-16 57.7 15.6 3.5 2 1 0 2 2 2 2 ZIP Zinc transporter Apc1 PF12859.2 CDJ64245.1 - 0.28 11.3 4.3 11 6.2 0.0 3.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 DUF3357 PF11837.3 CDJ64245.1 - 0.37 10.6 8.0 1.8 8.4 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3357) Methyltransf_26 PF13659.1 CDJ64246.1 - 8.6e-09 35.4 0.0 5e-08 32.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDJ64246.1 - 0.022 14.1 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Sporozoite_P67 PF05642.6 CDJ64246.1 - 0.036 11.9 1.4 0.065 11.0 0.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.4 CDJ64246.1 - 1.5 8.2 20.5 0.89 8.9 9.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDJ64246.1 - 2.2 7.9 11.0 3.3 7.3 7.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SNARE PF05739.14 CDJ64247.1 - 1.3e-08 34.3 2.0 1.3e-08 34.3 1.4 2.0 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 CDJ64247.1 - 0.0095 15.4 9.4 0.016 14.6 6.5 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 Fusion_gly PF00523.13 CDJ64247.1 - 0.011 13.8 0.4 0.015 13.3 0.3 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Syntaxin-6_N PF09177.6 CDJ64247.1 - 0.013 15.8 0.3 0.013 15.8 0.2 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF2218 PF09981.4 CDJ64247.1 - 0.078 13.1 1.7 0.4 10.8 0.2 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) COX16 PF14138.1 CDJ64247.1 - 0.44 10.7 7.3 0.23 11.6 3.4 1.9 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 BAF1_ABF1 PF04684.8 CDJ64247.1 - 0.98 8.1 9.9 1.7 7.3 6.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CDJ64247.1 - 1.2 8.5 8.4 1.5 8.1 5.5 1.4 1 1 0 1 1 1 0 Spt20 family TraW_N PF12477.3 CDJ64247.1 - 1.8 8.5 0.0 1.8 8.5 0.0 3.1 2 1 0 2 2 1 0 Sex factor F TraW protein N terminal SPX PF03105.14 CDJ64247.1 - 2.7 7.6 10.2 3.7 7.2 7.0 1.3 1 1 0 1 1 1 0 SPX domain Tropomyosin PF00261.15 CDJ64247.1 - 6.9 5.6 15.3 1.7 7.6 0.4 2.2 2 0 0 2 2 2 0 Tropomyosin DUF2721 PF11026.3 CDJ64247.1 - 8.1 6.1 13.0 1 9.0 1.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF2721) Ycf1 PF05758.7 CDJ64249.1 - 0.005 14.6 5.9 0.05 11.3 0.5 2.0 2 0 0 2 2 2 2 Ycf1 Spore_coat_CotO PF14153.1 CDJ64249.1 - 0.19 11.1 23.3 0.85 9.0 6.4 2.2 2 0 0 2 2 2 0 Spore coat protein CotO PAT1 PF09770.4 CDJ64249.1 - 0.29 9.3 51.3 0.57 8.3 9.4 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 CDJ64249.1 - 9.7 5.6 18.2 3.3 7.1 3.8 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.11 CDJ64249.1 - 9.9 5.9 12.0 3.6 7.4 2.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 CDJ64253.1 - 0.052 12.1 0.0 0.052 12.1 0.0 4.4 4 2 1 5 5 5 0 LMBR1-like membrane protein adh_short PF00106.20 CDJ64254.1 - 3.2e-26 92.2 2.8 3.2e-26 92.2 1.9 1.9 2 0 0 2 2 2 1 short chain dehydrogenase SCP2 PF02036.12 CDJ64254.1 - 1.8e-18 66.6 0.0 4.4e-15 55.8 0.0 2.7 2 0 0 2 2 2 2 SCP-2 sterol transfer family KR PF08659.5 CDJ64254.1 - 2.3e-12 46.9 1.6 4.5e-12 45.9 1.1 1.5 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.1 CDJ64254.1 - 0.14 12.1 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal Nfu_N PF08712.6 CDJ64255.1 - 3.6e-20 71.3 0.1 1.2e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CDJ64255.1 - 2.2e-05 24.1 0.0 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NifU-like domain DUF3108 PF11306.3 CDJ64257.1 - 0.028 14.0 1.6 0.055 13.1 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3108) MscS_TM PF12794.2 CDJ64257.1 - 0.17 10.4 2.0 0.27 9.7 1.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1517 PF07466.6 CDJ64257.1 - 0.61 9.0 7.4 0.89 8.4 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Gag_p17 PF00540.13 CDJ64258.1 - 0.19 11.4 0.0 0.19 11.4 0.0 4.7 7 0 0 7 7 7 0 gag gene protein p17 (matrix protein) Bul1_C PF04426.7 CDJ64259.1 - 0.0091 15.2 0.6 0.076 12.1 0.0 2.2 2 0 0 2 2 2 1 Bul1 C terminus Rax2 PF12768.2 CDJ64259.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PBP1_TM PF14812.1 CDJ64259.1 - 0.41 10.9 5.6 0.071 13.4 0.9 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SID-1_RNA_chan PF13965.1 CDJ64259.1 - 1.2 7.2 1.6 2.4 6.2 1.0 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Pkinase PF00069.20 CDJ64261.1 - 2.8e-22 79.0 0.0 6.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDJ64261.1 - 9.5e-13 47.7 0.0 1.4e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDJ64261.1 - 1.8e-10 40.3 0.0 3.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CDJ64261.1 - 0.00027 20.0 0.0 0.00047 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDJ64261.1 - 0.0011 18.7 1.2 0.0011 18.7 0.8 2.5 3 1 0 3 3 3 1 Phosphotransferase enzyme family PIP49_C PF12260.3 CDJ64261.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.15 CDJ64261.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 CDJ64262.1 - 5.4e-19 68.3 0.0 1.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDJ64262.1 - 1.7e-08 33.7 0.0 2.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDJ64262.1 - 2.1e-06 26.9 0.0 4.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CDJ64262.1 - 0.011 14.8 0.0 0.029 13.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDJ64262.1 - 0.029 14.1 0.1 0.029 14.1 0.1 3.0 2 2 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDJ64262.1 - 0.23 11.0 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 CDJ64263.1 - 8.7e-17 61.1 0.0 2e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64263.1 - 3.2e-05 23.1 0.0 5.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ64263.1 - 9.8e-05 21.4 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDJ64263.1 - 0.037 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP_bind_1 PF03029.12 CDJ64264.1 - 1.6e-65 220.9 0.0 4.6e-61 206.3 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Ribosomal_60s PF00428.14 CDJ64264.1 - 6.3e-06 26.5 5.6 1.1e-05 25.7 3.0 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein AAA_17 PF13207.1 CDJ64264.1 - 1.3e-05 26.0 0.7 3.9e-05 24.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CDJ64264.1 - 2.4e-05 24.3 1.7 5.1e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDJ64264.1 - 0.00018 21.6 0.0 0.00042 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 CDJ64264.1 - 0.00089 18.7 0.0 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 CDJ64264.1 - 0.0023 16.7 0.0 0.004 15.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 CDJ64264.1 - 0.0024 18.1 1.0 0.0084 16.4 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDJ64264.1 - 0.0027 17.1 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CDJ64264.1 - 0.0029 17.9 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 CDJ64264.1 - 0.0038 16.9 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA12 PF10443.4 CDJ64264.1 - 0.004 15.7 0.0 0.19 10.1 0.0 2.1 2 0 0 2 2 2 1 RNA12 protein AAA_10 PF12846.2 CDJ64264.1 - 0.0053 16.2 0.0 0.024 14.0 0.0 2.0 2 1 1 3 3 3 1 AAA-like domain AAA_14 PF13173.1 CDJ64264.1 - 0.0073 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDJ64264.1 - 0.0096 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CDJ64264.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 CDJ64264.1 - 0.015 14.4 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 CDJ64264.1 - 0.017 14.0 0.2 0.051 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 CDJ64264.1 - 0.017 14.8 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CDJ64264.1 - 0.022 14.4 0.1 0.068 12.9 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain AAA PF00004.24 CDJ64264.1 - 0.024 14.8 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CDJ64264.1 - 0.029 13.9 0.3 0.06 12.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 CDJ64264.1 - 0.03 14.2 0.1 0.075 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 CDJ64264.1 - 0.031 13.3 0.5 0.11 11.5 0.0 2.0 2 1 1 3 3 3 0 Zeta toxin cobW PF02492.14 CDJ64264.1 - 0.033 13.6 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CDJ64264.1 - 0.034 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CbiA PF01656.18 CDJ64264.1 - 0.036 13.4 0.0 0.09 12.1 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Paf1 PF03985.8 CDJ64264.1 - 0.038 12.7 1.5 0.054 12.2 1.0 1.2 1 0 0 1 1 1 0 Paf1 SRP54 PF00448.17 CDJ64264.1 - 0.059 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_PrkA PF08298.6 CDJ64264.1 - 0.069 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Nucleoplasmin PF03066.10 CDJ64264.1 - 0.083 12.4 2.8 0.2 11.2 2.0 1.6 1 0 0 1 1 1 0 Nucleoplasmin ADK PF00406.17 CDJ64264.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Adenylate kinase MMR_HSR1 PF01926.18 CDJ64264.1 - 0.13 12.2 0.0 0.55 10.1 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 CDJ64264.1 - 0.15 10.6 0.0 0.15 10.6 0.0 2.3 2 1 0 2 2 1 0 G-protein alpha subunit BNIP3 PF06553.7 CDJ64264.1 - 0.33 10.3 2.1 0.52 9.6 1.5 1.2 1 0 0 1 1 1 0 BNIP3 eIF-3_zeta PF05091.7 CDJ64265.1 - 3.9e-143 477.7 0.0 5.4e-143 477.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Cullin PF00888.17 CDJ64266.1 - 1.6e-27 96.3 23.6 5.5e-21 74.7 9.7 3.4 3 1 0 3 3 3 2 Cullin family RRM_1 PF00076.17 CDJ64267.1 - 3.8e-05 23.2 0.0 9.2e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ64267.1 - 0.00036 20.3 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF2A PF08662.6 CDJ64267.1 - 0.0041 16.8 0.2 0.013 15.2 0.1 1.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 CDJ64267.1 - 0.03 14.3 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Gemini_coat PF00844.13 CDJ64268.1 - 0.23 10.6 0.5 0.45 9.6 0.0 1.7 2 0 0 2 2 2 0 Geminivirus coat protein/nuclear export factor BR1 family SR-25 PF10500.4 CDJ64269.1 - 0.0024 17.4 18.8 0.0024 17.4 13.0 3.2 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Hist_deacetyl PF00850.14 CDJ64269.1 - 4.1 6.6 7.4 0.84 8.8 1.3 2.1 2 0 0 2 2 2 0 Histone deacetylase domain Peptidase_S30 PF01577.11 CDJ64269.1 - 5.3 6.3 14.7 2.6 7.3 4.4 2.1 2 0 0 2 2 2 0 Potyvirus P1 protease SbcCD_C PF13558.1 CDJ64270.1 - 0.0069 16.2 1.6 0.0084 16.0 0.1 1.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit TetR_C PF02909.12 CDJ64270.1 - 0.022 14.3 0.7 0.022 14.3 0.5 2.0 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain BRF1 PF07741.8 CDJ64270.1 - 0.21 11.8 11.5 1.8 8.8 2.1 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF4355 PF14265.1 CDJ64270.1 - 0.75 9.7 17.2 0.2 11.6 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) RNA_pol_Rbc25 PF08292.7 CDJ64270.1 - 4.9 7.3 5.9 5.2 7.2 0.3 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 FliD_N PF02465.13 CDJ64271.1 - 0.007 16.7 5.7 0.01 16.1 3.9 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus DUF755 PF05501.6 CDJ64271.1 - 0.012 15.6 17.4 0.018 15.1 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF572 PF04502.8 CDJ64271.1 - 0.045 12.9 1.1 0.057 12.6 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4003 PF13170.1 CDJ64271.1 - 0.047 12.9 0.2 0.063 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Syja_N PF02383.13 CDJ64271.1 - 0.1 11.3 2.0 0.12 11.0 1.4 1.1 1 0 0 1 1 1 0 SacI homology domain IPK PF03770.11 CDJ64271.1 - 0.17 11.5 3.2 0.21 11.1 2.2 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase Mcm10 PF09332.6 CDJ64271.1 - 1 8.6 4.4 1.3 8.3 3.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor WD40 PF00400.27 CDJ64272.1 - 1.3e-23 81.9 10.6 9.6e-07 28.4 0.1 7.4 7 2 0 7 7 7 5 WD domain, G-beta repeat Med15 PF09606.5 CDJ64272.1 - 5.1 5.1 30.0 0.089 10.9 15.0 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ64272.1 - 9.1 5.9 6.9 16 5.1 4.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SoxE PF06525.6 CDJ64273.1 - 8.9 5.5 8.6 17 4.6 2.3 2.4 2 0 0 2 2 2 0 Sulfocyanin (SoxE) RCC1_2 PF13540.1 CDJ64274.1 - 5.2e-09 35.4 10.1 0.0022 17.5 0.1 5.0 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CDJ64274.1 - 3.4e-07 30.3 1.0 0.4 10.9 0.0 5.6 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Med15 PF09606.5 CDJ64274.1 - 1.3e-05 23.6 41.5 2.6e-05 22.6 4.3 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ64274.1 - 0.033 14.1 23.0 0.15 11.9 1.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATG2_CAD PF13329.1 CDJ64274.1 - 1.1 8.8 4.6 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif eIF-3_zeta PF05091.7 CDJ64274.1 - 1.3 7.5 15.1 3.3 6.2 5.2 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AUX_IAA PF02309.11 CDJ64274.1 - 1.4 8.5 8.9 16 5.1 3.7 2.2 2 0 0 2 2 2 0 AUX/IAA family DUF2407_C PF13373.1 CDJ64274.1 - 1.6 8.6 7.0 4.8 7.1 0.6 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain CDK5_activator PF03261.10 CDJ64274.1 - 1.9 7.7 11.7 0.26 10.5 2.5 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein CD20 PF04103.10 CDJ64274.1 - 1.9 8.3 4.7 7.2 6.5 0.4 2.3 2 0 0 2 2 2 0 CD20-like family OmpH PF03938.9 CDJ64274.1 - 3.3 7.6 36.2 0.11 12.4 4.1 2.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Presenilin PF01080.12 CDJ64274.1 - 4.2 6.0 5.7 1.8 7.2 1.8 1.7 2 0 0 2 2 2 0 Presenilin DivIC PF04977.10 CDJ64274.1 - 8.4 5.9 29.3 1 8.9 4.4 3.3 3 0 0 3 3 3 0 Septum formation initiator Rpp20 PF12328.3 CDJ64274.1 - 9.9 5.8 17.0 1.8 8.2 0.1 3.1 2 1 1 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P zf-CCHC_6 PF15288.1 CDJ64275.1 - 4.6 7.0 5.8 5.6 6.7 1.7 2.5 1 1 1 2 2 2 0 Zinc knuckle DUF1777 PF08648.7 CDJ64275.1 - 8.1 6.1 18.1 12 5.6 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Rhomboid PF01694.17 CDJ64276.1 - 1.4e-16 60.8 7.6 5.1e-16 59.0 5.3 2.0 1 0 0 1 1 1 1 Rhomboid family Pkinase PF00069.20 CDJ64276.1 - 0.22 10.6 3.2 0.43 9.6 0.0 2.6 2 1 0 2 2 2 0 Protein kinase domain SPX PF03105.14 CDJ64276.1 - 1.5 8.4 24.6 1.1 8.9 0.3 2.5 2 0 0 2 2 2 0 SPX domain Spt20 PF12090.3 CDJ64277.1 - 0.19 11.0 16.4 1.4 8.2 5.7 2.4 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDJ64277.1 - 0.59 9.1 29.4 0.24 10.4 10.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein Zip PF02535.17 CDJ64277.1 - 4.9 6.0 7.4 21 3.9 2.6 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 CDJ64278.1 - 0.00039 19.4 26.2 0.00039 19.4 18.1 3.3 2 1 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor SpaB_C PF14028.1 CDJ64278.1 - 0.9 9.0 28.2 0.61 9.5 10.0 2.2 2 0 0 2 2 2 0 SpaB C-terminal domain Med15 PF09606.5 CDJ64279.1 - 0.00013 20.4 16.1 0.00013 20.3 11.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Phage_base_V PF04717.7 CDJ64279.1 - 0.095 12.6 0.3 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Phage-related baseplate assembly protein TFIIA PF03153.8 CDJ64279.1 - 0.14 11.9 12.5 0.18 11.6 8.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4638 PF15472.1 CDJ64279.1 - 0.15 11.5 2.2 0.16 11.5 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PIH1 PF08190.7 CDJ64279.1 - 0.2 11.0 6.9 0.23 10.8 4.8 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Peptidase_S64 PF08192.6 CDJ64279.1 - 0.7 8.1 3.3 0.69 8.1 2.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 TPX2 PF06886.6 CDJ64279.1 - 1.1 9.3 13.3 1.8 8.6 9.2 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Hid1 PF12722.2 CDJ64279.1 - 1.5 6.4 4.7 1.8 6.1 3.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BAF1_ABF1 PF04684.8 CDJ64279.1 - 2.8 6.7 26.4 0.029 13.2 9.6 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CDK5_activator PF03261.10 CDJ64279.1 - 4.9 6.3 9.7 6.6 5.9 6.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AUX_IAA PF02309.11 CDJ64279.1 - 5.6 6.6 7.3 7.9 6.1 5.0 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF4557 PF15101.1 CDJ64279.1 - 7.2 6.3 13.3 11 5.7 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDJ64279.1 - 7.3 4.6 20.9 8.8 4.4 14.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ERO1 PF04137.10 CDJ64280.1 - 1.3e-31 109.8 2.2 1.4e-27 96.6 0.5 2.2 2 0 0 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PXA PF02194.10 CDJ64281.1 - 0.092 12.3 2.1 0.069 12.7 0.3 1.7 2 0 0 2 2 2 0 PXA domain SR-25 PF10500.4 CDJ64281.1 - 0.25 10.7 4.2 0.36 10.2 0.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ArsA_ATPase PF02374.10 CDJ64282.1 - 1.8e-40 138.8 0.0 2.1e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CDJ64282.1 - 1.5e-12 47.2 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CDJ64282.1 - 4.4e-07 29.9 0.0 5.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CDJ64282.1 - 2.9e-06 26.6 0.0 4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CDJ64282.1 - 0.0004 19.8 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CDJ64282.1 - 0.00045 19.9 0.3 0.00087 19.0 0.2 1.5 1 1 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CDJ64282.1 - 0.0024 17.2 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein NB-ARC PF00931.17 CDJ64282.1 - 0.0035 16.2 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain T2SE PF00437.15 CDJ64282.1 - 0.0038 16.1 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MipZ PF09140.6 CDJ64282.1 - 0.0073 15.4 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ APS_kinase PF01583.15 CDJ64282.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 CDJ64282.1 - 0.015 14.7 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDJ64282.1 - 0.019 15.3 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.6 CDJ64282.1 - 0.019 14.0 0.1 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein Zeta_toxin PF06414.7 CDJ64282.1 - 0.021 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 CDJ64282.1 - 0.024 14.6 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain YhjQ PF06564.7 CDJ64282.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.4 2 0 0 2 2 2 0 YhjQ protein ResIII PF04851.10 CDJ64282.1 - 0.03 14.1 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 CDJ64282.1 - 0.05 13.2 0.7 0.1 12.2 0.4 1.5 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CDJ64282.1 - 0.058 14.2 0.2 0.077 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 CDJ64282.1 - 0.087 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.22 CDJ64282.1 - 0.088 13.1 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 CDJ64282.1 - 0.089 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 CDJ64282.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 CDJ64282.1 - 0.15 10.9 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ribosomal_L6e PF01159.14 CDJ64283.1 - 8e-33 112.9 1.4 1.1e-32 112.4 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Kelch_3 PF13415.1 CDJ64284.1 - 2.7e-23 81.5 0.7 2e-08 34.1 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CDJ64284.1 - 1.5e-17 63.1 0.8 8.7e-05 22.2 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ64284.1 - 3.5e-13 49.1 0.8 0.0022 17.8 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 CDJ64284.1 - 1.1e-09 37.9 0.0 0.47 10.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 CDJ64284.1 - 2.1e-08 33.6 1.9 0.21 11.4 0.7 5.0 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 CDJ64284.1 - 0.0012 18.3 0.0 6.5 6.3 0.0 4.1 4 0 0 4 4 4 1 Kelch motif DDHD PF02862.12 CDJ64284.1 - 0.87 9.3 7.4 1.2 8.9 0.3 2.7 3 0 0 3 3 3 0 DDHD domain Prefoldin PF02996.12 CDJ64284.1 - 3.3 7.3 10.2 2.4 7.8 0.7 2.7 2 0 0 2 2 2 0 Prefoldin subunit GTP_EFTU PF00009.22 CDJ64288.1 - 2.7e-52 176.9 0.0 8.1e-52 175.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CDJ64288.1 - 6.7e-27 93.4 0.0 6.7e-27 93.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 CDJ64288.1 - 1.5e-22 79.2 0.1 3.1e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CDJ64288.1 - 1.8e-19 69.3 0.0 5e-19 67.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CDJ64288.1 - 1.1e-09 38.2 0.0 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Septin PF00735.13 CDJ64288.1 - 0.26 10.2 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Septin Suf PF05843.9 CDJ64288.1 - 4.8 6.8 5.7 0.6 9.7 0.7 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3496 PF12001.3 CDJ64289.1 - 0.082 13.1 2.9 0.15 12.3 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) IFP_35_N PF07334.8 CDJ64289.1 - 0.2 11.6 2.1 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Geminin PF07412.7 CDJ64289.1 - 0.5 10.0 5.0 0.53 9.9 1.4 2.3 1 1 1 2 2 2 0 Geminin CIAPIN1 PF05093.8 CDJ64289.1 - 5.3 7.1 12.8 4.3 7.4 7.1 2.0 1 1 1 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SEP PF08059.8 CDJ64291.1 - 3.1e-19 69.0 0.1 4.9e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CDJ64291.1 - 6.4e-14 51.7 0.0 9.6e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain Pribosyltran PF00156.22 CDJ64292.1 - 1.8e-13 50.3 0.0 4.3e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Nucleoside_tran PF01733.13 CDJ64293.1 - 6.8e-17 61.5 6.5 6.8e-17 61.5 4.5 2.4 2 1 0 2 2 2 2 Nucleoside transporter BAF1_ABF1 PF04684.8 CDJ64293.1 - 0.91 8.3 2.9 1.5 7.5 2.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PARP PF00644.15 CDJ64298.1 - 6.8e-58 195.4 0.0 1.4e-57 194.5 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 CDJ64298.1 - 1.7e-30 105.4 1.2 3.4e-30 104.4 0.8 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 CDJ64298.1 - 6.7e-11 41.9 0.5 2.1e-10 40.4 0.4 1.9 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 CDJ64298.1 - 8.8e-07 28.9 0.0 2.2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-PARP PF00645.13 CDJ64298.1 - 1.3e-06 28.5 0.0 3.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PTCB-BRCT PF12738.2 CDJ64298.1 - 0.022 14.6 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain Ribosomal_L27e PF01777.13 CDJ64299.1 - 4.4e-22 78.0 4.2 5.6e-22 77.6 2.9 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CDJ64299.1 - 0.00013 21.5 1.6 0.00026 20.5 1.1 1.5 1 0 0 1 1 1 1 KOW motif Imm17 PF15591.1 CDJ64299.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 17 RRM_5 PF13893.1 CDJ64304.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyoxalase_2 PF12681.2 CDJ64305.1 - 2.4e-10 40.9 1.5 0.024 15.2 0.0 4.8 3 2 0 3 3 3 3 Glyoxalase-like domain Glyoxalase PF00903.20 CDJ64305.1 - 4e-05 23.5 0.0 0.056 13.4 0.0 3.4 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 CDJ64305.1 - 0.074 13.0 2.8 1.2 9.1 0.4 3.2 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CDC37_N PF03234.9 CDJ64305.1 - 3 8.1 16.8 7.4 6.8 11.6 1.7 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding IF3_C PF00707.17 CDJ64306.1 - 5.8e-18 64.4 0.0 2.7e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain TFIIA PF03153.8 CDJ64306.1 - 2.5 7.8 17.9 3.1 7.5 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DCP1 PF06058.8 CDJ64307.1 - 5.5e-15 55.4 0.0 2.1e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Dcp1-like decapping family GSH_synth_ATP PF03917.12 CDJ64308.1 - 2e-46 158.2 0.0 1.9e-27 95.8 0.0 5.4 4 2 1 5 5 5 3 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CDJ64308.1 - 1e-13 51.2 3.6 6.6e-10 39.0 0.0 3.5 3 0 0 3 3 3 2 Eukaryotic glutathione synthase SR-25 PF10500.4 CDJ64308.1 - 0.0047 16.4 1.3 0.0047 16.4 0.9 4.4 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein DUF1117 PF06547.7 CDJ64308.1 - 3.4 7.7 8.4 3 7.9 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) zf-C3HC4 PF00097.20 CDJ64309.1 - 1.1e-05 24.9 14.1 1.9e-05 24.2 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ64309.1 - 1.2e-05 25.2 15.3 1.9e-05 24.5 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ64309.1 - 3.9e-05 23.3 13.4 6.7e-05 22.6 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CDJ64309.1 - 4.9e-05 22.9 12.9 7.7e-05 22.2 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ64309.1 - 0.00041 20.0 12.6 0.00069 19.2 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 CDJ64309.1 - 0.0055 16.4 8.0 0.011 15.4 5.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CDJ64309.1 - 0.049 13.3 9.8 0.18 11.5 6.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CDJ64309.1 - 0.093 12.6 12.7 0.21 11.5 8.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CDJ64309.1 - 0.12 11.9 10.0 0.22 11.1 6.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CDJ64309.1 - 0.7 9.4 8.6 1.5 8.3 6.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.20 CDJ64310.1 - 2e-70 236.9 0.3 2.9e-70 236.3 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64310.1 - 6.7e-37 126.9 0.1 9.8e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CDJ64310.1 - 1.5e-28 95.8 9.0 6.1e-07 28.2 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 CDJ64310.1 - 2.1e-24 83.7 7.8 2.3e-07 29.8 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDJ64310.1 - 8e-24 83.5 7.4 1.1e-09 38.3 0.3 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CDJ64310.1 - 2.6e-22 76.6 4.1 9e-05 22.0 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CDJ64310.1 - 5.9e-13 48.2 8.4 0.00074 19.0 0.2 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CDJ64310.1 - 6.2e-06 25.8 4.1 0.006 16.3 0.0 3.6 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Kdo PF06293.9 CDJ64310.1 - 9.7e-06 24.7 0.1 2e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.4 CDJ64310.1 - 3.2e-05 23.9 0.2 0.19 11.7 0.2 3.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.1 CDJ64310.1 - 0.00014 20.9 0.1 0.0005 19.1 0.1 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CDJ64310.1 - 0.0099 15.6 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CDJ64310.1 - 0.017 14.4 0.0 0.062 12.6 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL EF-hand_10 PF14788.1 CDJ64310.1 - 0.022 14.3 0.1 0.69 9.6 0.0 3.0 3 0 0 3 3 3 0 EF hand OmpH PF03938.9 CDJ64311.1 - 0.0033 17.3 0.0 0.0033 17.3 0.0 14.8 6 5 2 8 8 8 2 Outer membrane protein (OmpH-like) WD40 PF00400.27 CDJ64312.1 - 2.3e-08 33.6 1.6 0.1 12.5 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2217 PF10265.4 CDJ64313.1 - 0.034 12.9 14.3 0.041 12.6 9.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF755 PF05501.6 CDJ64313.1 - 0.04 13.9 26.5 0.057 13.4 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Tetraspannin PF00335.15 CDJ64313.1 - 0.046 12.9 3.8 0.053 12.7 2.6 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF3487 PF11990.3 CDJ64313.1 - 0.075 12.4 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF677 PF05055.7 CDJ64313.1 - 0.096 11.3 3.2 0.12 11.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Halogen_Hydrol PF10112.4 CDJ64313.1 - 0.14 11.5 2.1 0.17 11.2 1.4 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3450 PF11932.3 CDJ64313.1 - 0.61 9.3 22.9 0.75 9.0 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HemX PF04375.9 CDJ64313.1 - 0.75 8.3 19.9 0.86 8.1 13.8 1.1 1 0 0 1 1 1 0 HemX DUF2215 PF10225.4 CDJ64313.1 - 0.8 9.0 5.7 1 8.7 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Med15 PF09606.5 CDJ64313.1 - 1.4 6.9 21.9 1.7 6.7 15.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 CDJ64313.1 - 1.6 8.8 7.6 2.4 8.2 5.2 1.4 1 1 0 1 1 1 0 Ctr copper transporter family DUF1675 PF07897.6 CDJ64313.1 - 1.7 8.4 10.5 2 8.2 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_S15 PF02129.13 CDJ64313.1 - 2.9 7.2 10.5 3.4 7.0 7.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4557 PF15101.1 CDJ64313.1 - 2.9 7.6 12.2 3.3 7.5 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Neur_chan_memb PF02932.11 CDJ64313.1 - 3.1 7.6 5.2 3.6 7.4 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.1 CDJ64313.1 - 4.4 8.2 8.3 5.6 7.8 5.7 1.3 1 0 0 1 1 1 0 Cdc42 effector DDRGK PF09756.4 CDJ64313.1 - 4.8 6.5 11.8 6.1 6.2 8.1 1.1 1 0 0 1 1 1 0 DDRGK domain OmpH PF03938.9 CDJ64313.1 - 8.4 6.3 24.7 11 5.9 17.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TFIIA PF03153.8 CDJ64313.1 - 9.5 6.0 17.3 10 5.9 12.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_5 PF13893.1 CDJ64314.1 - 6.1e-08 32.3 0.0 4.6e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ64314.1 - 5.1e-06 26.0 0.0 0.00088 18.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ64314.1 - 0.23 11.4 0.3 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 CDJ64316.1 - 0.0047 16.8 1.5 0.0047 16.8 1.0 4.9 4 1 1 5 5 5 2 short chain dehydrogenase DUF2722 PF10846.3 CDJ64316.1 - 0.027 13.5 0.1 0.027 13.5 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) CD20 PF04103.10 CDJ64316.1 - 3.6 7.5 14.5 3.6 7.4 1.8 4.3 4 1 1 5 5 5 0 CD20-like family DUF898 PF05987.8 CDJ64316.1 - 6.3 5.5 10.3 0.083 11.7 1.4 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Dehydrin PF00257.14 CDJ64318.1 - 3.9 7.7 6.3 1.2e+02 2.9 4.3 2.3 1 1 0 1 1 1 0 Dehydrin Pkinase PF00069.20 CDJ64321.1 - 2.7e-66 223.4 0.0 4.9e-66 222.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64321.1 - 9e-30 103.5 0.0 6e-29 100.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase SRP-alpha_N PF04086.8 CDJ64321.1 - 1.4 8.2 5.1 2.4 7.4 3.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NAD_binding_1 PF00175.16 CDJ64322.1 - 4.4e-16 59.4 0.0 6.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CDJ64322.1 - 0.0022 18.0 0.0 0.0062 16.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain UPF0181 PF03701.9 CDJ64323.1 - 0.0017 17.5 1.9 0.012 14.8 0.3 2.7 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0181) B12-binding_2 PF02607.12 CDJ64324.1 - 0.012 15.5 0.1 0.043 13.8 0.1 2.0 1 0 0 1 1 1 0 B12 binding domain Chromo PF00385.19 CDJ64325.1 - 5.4e-14 51.6 0.0 1.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 CDJ64327.1 - 7e-06 25.7 0.8 7e-06 25.7 0.6 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDJ64327.1 - 0.087 12.3 1.9 0.18 11.3 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ64327.1 - 7.9 6.2 10.1 1.5 8.5 3.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.12 CDJ64328.1 - 0.0041 17.1 0.0 0.0097 15.9 0.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein START PF01852.14 CDJ64331.1 - 3.7e-20 72.1 0.2 5.8e-20 71.4 0.2 1.3 1 0 0 1 1 1 1 START domain MEDS PF14417.1 CDJ64331.1 - 0.0018 17.3 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF3074 PF11274.3 CDJ64331.1 - 0.0027 17.3 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) CitX PF03802.9 CDJ64331.1 - 0.02 14.3 0.0 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Rhabdo_glycop PF00974.13 CDJ64333.1 - 0.23 9.6 0.7 0.38 8.9 0.5 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Ribosomal_60s PF00428.14 CDJ64334.1 - 0.022 15.1 4.8 0.022 15.1 3.4 4.8 4 1 1 5 5 5 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ64334.1 - 0.046 13.2 22.0 0.082 12.3 0.2 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein CD20 PF04103.10 CDJ64334.1 - 0.092 12.6 8.4 0.71 9.8 1.2 3.2 2 1 1 3 3 3 0 CD20-like family APC_CDC26 PF10471.4 CDJ64334.1 - 0.12 13.1 37.7 0.52 11.0 3.9 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 SprA-related PF12118.3 CDJ64334.1 - 0.4 9.9 58.6 1.2 8.3 7.2 3.2 3 0 0 3 3 3 0 SprA-related family G-alpha PF00503.15 CDJ64334.1 - 2.9 6.4 13.9 0.049 12.3 2.4 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Phostensin_N PF13916.1 CDJ64334.1 - 3.6 7.6 25.6 5.1 7.1 1.7 3.8 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal DUF912 PF06024.7 CDJ64334.1 - 9 6.4 9.3 19 5.4 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TFIIA PF03153.8 CDJ64335.1 - 1.6 8.5 5.3 1.6 8.5 3.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAP PF07174.6 CDJ64335.1 - 5.2 6.2 27.8 8.6 5.5 19.3 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Claudin_2 PF13903.1 CDJ64336.1 - 1.4 8.5 17.2 0.015 15.0 4.9 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RAB3GAP2_N PF14655.1 CDJ64336.1 - 2.6 6.9 9.3 3.1 6.6 6.2 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RRM_1 PF00076.17 CDJ64337.1 - 1.1e-15 56.9 0.1 2.4e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ64337.1 - 2.4e-11 43.4 0.0 3.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ64337.1 - 1.9e-08 33.9 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gate PF07670.9 CDJ64338.1 - 0.0044 16.9 0.4 0.016 15.0 0.3 2.1 1 1 0 1 1 1 1 Nucleoside recognition TauE PF01925.14 CDJ64339.1 - 9.6e-11 41.5 28.8 7.1e-07 28.9 8.8 3.1 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE TMEM154 PF15102.1 CDJ64339.1 - 0.04 13.6 0.3 0.04 13.6 0.2 2.1 2 0 0 2 2 2 0 TMEM154 protein family WBP-1 PF11669.3 CDJ64339.1 - 0.13 12.3 7.3 0.36 10.9 0.2 3.6 3 0 0 3 3 3 0 WW domain-binding protein 1 Ctr PF04145.10 CDJ64339.1 - 0.3 11.1 5.6 1.3 9.0 2.5 2.7 2 0 0 2 2 2 0 Ctr copper transporter family BatD PF13584.1 CDJ64339.1 - 0.31 9.5 5.1 3 6.3 1.7 2.2 2 0 0 2 2 2 0 Oxygen tolerance EMP24_GP25L PF01105.19 CDJ64339.1 - 0.61 9.7 5.3 5.4 6.6 0.0 2.8 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD PRA1 PF03208.14 CDJ64339.1 - 1 8.6 0.0 1 8.6 0.0 3.1 4 0 0 4 4 4 0 PRA1 family protein Adaptin_binding PF10199.4 CDJ64339.1 - 2 8.6 10.3 0.16 12.2 2.4 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TMEM51 PF15345.1 CDJ64339.1 - 3.4 7.3 12.8 0.35 10.5 5.4 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 YfhO PF09586.5 CDJ64339.1 - 5.9 4.7 7.2 0.17 9.8 0.1 2.0 2 1 0 2 2 2 0 Bacterial membrane protein YfhO LZ_Tnp_IS66 PF13007.2 CDJ64341.1 - 4.3 8.0 19.1 3.8 8.2 4.1 2.9 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain GTP_EFTU PF00009.22 CDJ64342.1 - 1e-09 38.0 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PAM2 PF07145.10 CDJ64342.1 - 0.015 14.7 0.0 0.045 13.2 0.0 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region GTP_EFTU PF00009.22 CDJ64343.1 - 3.8e-26 91.6 0.0 5.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CDJ64343.1 - 3.4e-06 27.1 0.0 6.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CDJ64343.1 - 0.00088 19.3 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ycf1 PF05758.7 CDJ64344.1 - 0.1 10.3 5.7 0.11 10.1 3.9 1.0 1 0 0 1 1 1 0 Ycf1 TFIIA PF03153.8 CDJ64344.1 - 0.39 10.5 15.3 0.52 10.1 10.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.14 CDJ64344.1 - 0.44 8.3 3.2 0.44 8.3 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.12 CDJ64344.1 - 2.7 7.7 9.0 0.45 10.2 3.8 1.6 2 0 0 2 2 2 0 DDHD domain HlyD_2 PF12700.2 CDJ64344.1 - 3.4 6.7 5.8 3.9 6.5 4.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Erythro-docking PF09277.6 CDJ64344.1 - 6.2 6.5 7.2 12 5.6 0.3 3.0 3 0 0 3 3 3 0 Erythronolide synthase, docking Surface_antigen PF11054.3 CDJ64347.1 - 6.9e-99 330.3 3.8 7.8e-99 330.1 2.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ64348.1 - 3e-90 302.0 1.2 3.5e-90 301.8 0.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ64349.1 - 3.2e-80 269.2 5.5 3.6e-80 269.0 3.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ64350.1 - 3.9e-84 282.0 3.9 4.5e-84 281.8 2.7 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ64351.1 - 2e-88 296.0 1.2 2.4e-88 295.8 0.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Big_1 PF02369.11 CDJ64351.1 - 0.077 12.9 0.9 0.19 11.6 0.1 2.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) GCD14 PF08704.5 CDJ64352.1 - 4e-63 213.1 0.0 4e-39 134.5 0.0 2.3 1 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CDJ64352.1 - 1.7e-07 30.9 0.0 0.00016 21.2 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ64352.1 - 3.7e-06 27.4 0.0 7.3e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CDJ64352.1 - 0.0061 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CDJ64352.1 - 0.0063 16.5 0.1 0.021 14.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CDJ64352.1 - 0.015 14.3 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase V_ATPase_I PF01496.14 CDJ64353.1 - 0.41 8.4 6.3 0.23 9.2 0.6 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Dfp1_Him1_M PF08630.5 CDJ64353.1 - 2 8.2 5.7 0.4 10.4 1.1 1.8 2 0 0 2 2 2 0 Dfp1/Him1, central region PRP1_N PF06424.7 CDJ64353.1 - 7.8 6.8 7.6 1.6 9.0 2.5 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal NUC153 PF08159.7 CDJ64356.1 - 2.2e-05 23.9 0.0 4.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NUC153 domain HSP20 PF00011.16 CDJ64357.1 - 9e-18 64.0 0.1 9e-18 64.0 0.0 2.2 2 1 1 3 3 3 1 Hsp20/alpha crystallin family Dehydrin PF00257.14 CDJ64357.1 - 0.0019 18.5 14.0 0.0019 18.5 9.7 3.9 3 2 0 3 3 3 1 Dehydrin RNA_pol_Rpb1_5 PF04998.12 CDJ64357.1 - 0.01 15.1 0.8 0.022 14.0 0.6 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Nha1_C PF08619.5 CDJ64359.1 - 0.00075 18.8 28.0 0.00092 18.5 19.4 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Med15 PF09606.5 CDJ64359.1 - 0.077 11.1 124.5 0.1 10.7 86.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ64359.1 - 0.16 10.1 98.2 0.19 9.9 68.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Atg14 PF10186.4 CDJ64359.1 - 0.2 10.5 49.0 0.27 10.1 33.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Dapper PF15268.1 CDJ64359.1 - 0.49 9.1 43.6 0.59 8.8 30.2 1.1 1 0 0 1 1 1 0 Dapper Daxx PF03344.10 CDJ64359.1 - 1.2 7.5 39.5 1.3 7.3 27.3 1.0 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 CDJ64359.1 - 3.6 5.6 51.4 4.5 5.3 35.6 1.0 1 0 0 1 1 1 0 Utp14 protein Caldesmon PF02029.10 CDJ64359.1 - 8.2 4.7 40.1 9.8 4.4 27.8 1.1 1 0 0 1 1 1 0 Caldesmon RVT_1 PF00078.22 CDJ64360.1 - 1.1e-18 67.4 0.0 2.1e-18 66.4 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CDJ64360.1 - 0.00083 19.6 0.0 0.0022 18.3 0.0 1.6 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.1 CDJ64360.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like FAM92 PF06730.6 CDJ64360.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 FAM92 protein rve PF00665.21 CDJ64361.1 - 1.2e-17 64.1 0.0 1.7e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ64361.1 - 0.066 12.7 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain Acetyltransf_1 PF00583.19 CDJ64363.1 - 1.7e-09 37.5 0.0 3.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDJ64363.1 - 6.8e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDJ64363.1 - 0.0018 18.3 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CDJ64363.1 - 0.12 12.1 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF966 PF06136.8 CDJ64363.1 - 0.13 11.6 6.6 0.22 10.9 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PAT1 PF09770.4 CDJ64363.1 - 0.9 7.6 5.8 1.2 7.2 4.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDJ64363.1 - 1.6 8.0 8.9 2.2 7.6 6.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4603 PF15376.1 CDJ64363.1 - 6.6 3.7 11.6 9 3.3 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MA3 PF02847.12 CDJ64365.1 - 5.6e-07 29.2 0.9 1.6e-06 27.8 0.6 1.7 1 0 0 1 1 1 1 MA3 domain VIT1 PF01988.14 CDJ64366.1 - 0.14 11.5 2.1 0.16 11.4 1.4 1.0 1 0 0 1 1 1 0 VIT family SprA-related PF12118.3 CDJ64366.1 - 0.26 10.5 21.1 0.29 10.4 14.6 1.1 1 0 0 1 1 1 0 SprA-related family RskA PF10099.4 CDJ64366.1 - 0.26 10.9 11.4 0.3 10.7 7.9 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF533 PF04391.7 CDJ64366.1 - 0.31 10.3 15.7 0.38 10.1 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) FHIPEP PF00771.15 CDJ64366.1 - 0.32 9.2 3.9 0.29 9.4 2.7 1.0 1 0 0 1 1 1 0 FHIPEP family Pex14_N PF04695.8 CDJ64366.1 - 0.36 10.8 10.3 0.39 10.7 7.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF_4EBP PF05456.6 CDJ64366.1 - 0.48 10.1 3.8 0.5 10.0 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF1800 PF08811.6 CDJ64366.1 - 0.49 9.2 10.1 0.48 9.3 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Suf PF05843.9 CDJ64366.1 - 0.56 9.8 11.4 0.57 9.8 7.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AIF_C PF14721.1 CDJ64366.1 - 0.63 10.2 3.5 0.68 10.1 2.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FlaG PF03646.10 CDJ64366.1 - 0.67 10.1 12.3 0.68 10.1 8.5 1.1 1 0 0 1 1 1 0 FlaG protein ASFV_J13L PF05568.6 CDJ64366.1 - 0.8 9.2 5.6 0.9 9.0 3.9 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF912 PF06024.7 CDJ64366.1 - 0.86 9.6 3.0 0.9 9.6 2.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CDJ64366.1 - 0.87 8.5 15.3 0.91 8.5 10.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF2782 PF11191.3 CDJ64366.1 - 0.97 9.4 5.9 1.2 9.1 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Gag_spuma PF03276.9 CDJ64366.1 - 1.1 7.4 12.2 1.1 7.4 8.5 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Activator_LAG-3 PF11498.3 CDJ64366.1 - 1.2 7.7 31.7 1.3 7.7 21.9 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Lycopene_cycl PF05834.7 CDJ64366.1 - 1.4 7.7 6.7 1.6 7.5 4.6 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein Spt20 PF12090.3 CDJ64366.1 - 1.6 8.0 8.5 1.7 7.9 5.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF4557 PF15101.1 CDJ64366.1 - 1.7 8.4 11.5 1.6 8.5 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) eIF3_subunit PF08597.5 CDJ64366.1 - 1.7 8.1 9.7 1.9 8.0 6.7 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Med15 PF09606.5 CDJ64366.1 - 1.8 6.7 29.7 1.7 6.7 20.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDJ64366.1 - 1.9 7.4 9.2 2.1 7.2 6.4 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3371 PF11851.3 CDJ64366.1 - 2 9.1 13.4 2.1 9.0 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) MelC1 PF06236.6 CDJ64366.1 - 2.4 8.1 8.2 2.8 7.9 5.7 1.1 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 DUF3138 PF11336.3 CDJ64366.1 - 2.9 5.9 10.0 3.8 5.5 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) EIIBC-GUT_N PF03612.9 CDJ64366.1 - 2.9 7.4 6.4 3.2 7.3 4.4 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DOR PF14839.1 CDJ64366.1 - 3.6 7.2 10.8 4 7.1 7.5 1.1 1 0 0 1 1 1 0 DOR family DUF2360 PF10152.4 CDJ64366.1 - 4 7.7 11.6 4.5 7.5 8.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) ERF PF04404.7 CDJ64366.1 - 4.2 6.8 13.6 4.8 6.7 9.5 1.1 1 0 0 1 1 1 0 ERF superfamily Aminotran_1_2 PF00155.16 CDJ64366.1 - 4.8 6.0 7.4 4.9 6.0 5.1 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II FCP1_C PF09309.5 CDJ64366.1 - 4.9 6.3 8.4 5.2 6.2 5.8 1.2 1 0 0 1 1 1 0 FCP1, C-terminal TFIIA PF03153.8 CDJ64366.1 - 5.3 6.8 20.3 4.9 6.9 14.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G0-G1_switch_2 PF15103.1 CDJ64366.1 - 5.9 7.1 7.6 6.6 7.0 5.3 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 R_equi_Vir PF05526.6 CDJ64366.1 - 6.3 6.3 6.6 6.6 6.3 4.6 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein PAT1 PF09770.4 CDJ64366.1 - 6.4 4.8 21.8 5.9 5.0 15.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BaxI_1 PF12811.2 CDJ64366.1 - 7.2 5.6 7.6 8.2 5.4 5.2 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Med13_N PF11597.3 CDJ64366.1 - 7.4 5.1 9.0 7.3 5.1 6.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF4175 PF13779.1 CDJ64366.1 - 7.7 4.0 22.7 7.8 4.0 15.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3373 PF11853.3 CDJ64366.1 - 9.3 4.6 12.4 11 4.4 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3597 PF12200.3 CDJ64366.1 - 9.3 6.6 10.1 11 6.3 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Serinc PF03348.10 CDJ64366.1 - 9.6 4.7 6.2 10 4.7 4.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.11 CDJ64367.1 - 0.0094 15.8 5.9 0.0094 15.8 4.1 3.1 1 1 1 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region TMEM247 PF15444.1 CDJ64369.1 - 0.42 10.4 3.0 0.43 10.3 2.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 247 DUF721 PF05258.7 CDJ64369.1 - 0.81 9.9 3.5 0.96 9.6 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF721) UPF0560 PF10577.4 CDJ64370.1 - 0.038 12.2 23.3 0.054 11.7 16.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF755 PF05501.6 CDJ64370.1 - 0.057 13.4 34.2 0.077 13.0 23.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Plasmodium_Vir PF05795.6 CDJ64370.1 - 0.058 12.5 7.0 0.072 12.2 4.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Band_3_cyto PF07565.8 CDJ64370.1 - 0.18 11.2 10.0 0.21 11.0 6.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.11 CDJ64370.1 - 0.25 11.1 11.8 0.28 11.0 8.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Draxin PF15550.1 CDJ64370.1 - 0.34 10.5 10.6 0.42 10.2 7.3 1.1 1 0 0 1 1 1 0 Draxin DUF2217 PF10265.4 CDJ64370.1 - 0.34 9.6 17.1 0.39 9.4 11.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Cwf_Cwc_15 PF04889.7 CDJ64370.1 - 0.38 10.4 12.9 0.64 9.6 9.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Drf_GBD PF06371.8 CDJ64370.1 - 0.94 8.8 8.9 1.3 8.3 6.2 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Herpes_env PF01673.13 CDJ64370.1 - 0.98 7.8 19.4 1.1 7.6 13.4 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Spc7_N PF15402.1 CDJ64370.1 - 1.2 7.0 24.4 1.4 6.8 16.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 eIF-3_zeta PF05091.7 CDJ64370.1 - 1.8 7.0 14.3 2.3 6.7 9.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex16 PF08610.5 CDJ64370.1 - 1.9 7.3 10.9 2.3 7.1 7.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) HGTP_anticodon2 PF12745.2 CDJ64370.1 - 3.1 6.8 10.6 3.8 6.5 7.4 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1387 PF07139.6 CDJ64370.1 - 3.2 7.2 22.1 3.6 7.0 15.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PLRV_ORF5 PF01690.12 CDJ64370.1 - 3.5 6.6 19.2 3.9 6.5 13.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAPS PF04499.10 CDJ64370.1 - 3.7 6.0 11.6 4 5.9 8.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC73 PF05179.9 CDJ64370.1 - 4.5 6.5 14.0 5.3 6.3 9.7 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Otopetrin PF03189.8 CDJ64370.1 - 4.6 6.1 6.6 5 6.0 4.6 1.2 1 0 0 1 1 1 0 Otopetrin Peptidase_S49_N PF08496.5 CDJ64370.1 - 5.1 6.8 8.8 9.8 5.9 6.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ASFV_J13L PF05568.6 CDJ64370.1 - 7 6.1 26.1 9 5.7 18.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Hid1 PF12722.2 CDJ64370.1 - 7 4.1 22.7 7.5 4.0 15.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RED_N PF07808.8 CDJ64370.1 - 8.9 5.4 18.4 15 4.6 12.7 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region vMSA PF00695.14 CDJ64370.1 - 9.1 5.3 9.9 11 5.1 6.9 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF202 PF02656.10 CDJ64371.1 - 3.6 7.8 13.8 1.6e+02 2.5 8.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Macoilin PF09726.4 CDJ64371.1 - 3.9 5.6 10.8 4.5 5.4 7.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Med15 PF09606.5 CDJ64371.1 - 5.8 4.9 27.5 8.2 4.4 19.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAP1 PF07218.6 CDJ64372.1 - 3.3 5.6 5.1 4.4 5.2 3.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FerI PF08151.7 CDJ64373.1 - 7.2e-06 25.9 0.0 13 5.9 0.0 6.4 5 2 2 7 7 7 3 FerI (NUC094) domain ODV-E18 PF10717.4 CDJ64374.1 - 0.11 11.9 1.4 0.33 10.4 1.0 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Spt20 PF12090.3 CDJ64374.1 - 0.2 10.9 13.8 0.18 11.1 0.7 2.2 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.5 CDJ64374.1 - 0.31 9.1 43.4 0.0083 14.3 12.8 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ64374.1 - 4.8 6.8 13.1 0.47 10.1 0.7 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3801 PF12687.2 CDJ64374.1 - 5 6.6 10.5 4.3 6.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DUF2722 PF10846.3 CDJ64374.1 - 6.6 5.6 17.9 0.12 11.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3722 PF12519.3 CDJ64374.1 - 7.3 5.7 6.9 11 5.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3722) Thioredoxin PF00085.15 CDJ64375.1 - 1.4e-12 47.1 0.6 3.8e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin SR-25 PF10500.4 CDJ64375.1 - 2.6e-05 23.8 18.2 3.5e-05 23.4 12.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Thioredoxin_7 PF13899.1 CDJ64375.1 - 0.00056 19.8 0.1 0.00056 19.8 0.0 2.2 2 1 0 2 2 1 1 Thioredoxin-like Med15 PF09606.5 CDJ64375.1 - 0.0021 16.3 15.7 0.0023 16.2 10.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 CDJ64375.1 - 0.0024 17.2 19.9 0.004 16.5 13.8 1.3 1 0 0 1 1 1 1 SprA-related family AAA_23 PF13476.1 CDJ64375.1 - 0.0073 16.6 7.2 0.0093 16.3 5.0 1.2 1 0 0 1 1 1 1 AAA domain DUF1645 PF07816.6 CDJ64375.1 - 0.017 15.5 11.4 0.027 14.9 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DUF4175 PF13779.1 CDJ64375.1 - 0.021 12.5 15.5 0.022 12.4 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Thioredoxin_8 PF13905.1 CDJ64375.1 - 0.021 14.9 1.8 0.028 14.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Suf PF05843.9 CDJ64375.1 - 0.091 12.4 11.1 0.13 12.0 7.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_S49_N PF08496.5 CDJ64375.1 - 0.12 12.1 6.2 0.16 11.7 4.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Corona_nucleoca PF00937.13 CDJ64375.1 - 0.12 11.2 17.1 0.15 10.9 11.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3801 PF12687.2 CDJ64375.1 - 0.12 11.8 9.8 0.17 11.4 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) CAF-1_p150 PF11600.3 CDJ64375.1 - 0.17 11.2 19.6 0.21 10.9 13.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4207 PF13904.1 CDJ64375.1 - 0.17 11.2 22.6 0.24 10.7 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Suc_Fer-like PF06999.7 CDJ64375.1 - 0.2 11.6 5.1 0.26 11.2 3.5 1.1 1 0 0 1 1 1 0 Sucrase/ferredoxin-like DUF2201_N PF13203.1 CDJ64375.1 - 0.35 10.0 9.8 0.44 9.6 6.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Thioredoxin_4 PF13462.1 CDJ64375.1 - 0.38 10.7 0.0 0.38 10.7 0.0 2.3 2 1 0 2 2 1 0 Thioredoxin Folate_carrier PF01770.13 CDJ64375.1 - 0.42 9.0 7.8 0.5 8.8 5.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier ZYG-11_interact PF05884.7 CDJ64375.1 - 0.55 9.2 7.8 0.66 9.0 5.4 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Thioredoxin_2 PF13098.1 CDJ64375.1 - 1.7 8.8 8.2 25 5.1 5.7 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain OATP PF03137.15 CDJ64375.1 - 2.2 6.2 5.5 3.2 5.7 3.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family G0-G1_switch_2 PF15103.1 CDJ64375.1 - 2.7 8.2 7.2 5.2 7.3 5.0 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 DDE_Tnp_1_2 PF13586.1 CDJ64375.1 - 4.5 7.5 6.1 18 5.5 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Sec62 PF03839.11 CDJ64375.1 - 5.8 6.2 8.0 7.5 5.8 5.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 FLO_LFY PF01698.11 CDJ64375.1 - 8.5 5.1 11.4 12 4.6 7.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Gag_spuma PF03276.9 CDJ64375.1 - 9 4.4 15.9 11 4.1 11.0 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF4201 PF13870.1 CDJ64377.1 - 0.72 9.2 20.5 0.86 9.0 9.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TSC22 PF01166.13 CDJ64377.1 - 2 8.4 16.4 0.57 10.1 2.3 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF2205 PF10224.4 CDJ64377.1 - 2.2 7.9 17.1 0.16 11.5 5.1 3.4 2 1 2 4 4 4 0 Predicted coiled-coil protein (DUF2205) TMCO5 PF14992.1 CDJ64377.1 - 3.7 6.5 15.1 0.15 11.1 6.6 1.6 2 0 0 2 2 2 0 TMCO5 family Rab5-bind PF09311.6 CDJ64377.1 - 4.7 7.0 28.4 1.5 8.6 1.8 2.8 2 1 1 3 3 3 0 Rabaptin-like protein Rootletin PF15035.1 CDJ64377.1 - 5.5 6.9 23.5 0.13 12.2 8.7 2.9 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion CAF-1_p150 PF11600.3 CDJ64377.1 - 6.8 6.0 19.5 0.094 12.0 8.4 1.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0242 PF06785.6 CDJ64377.1 - 9.4 4.7 12.3 11 4.5 8.4 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) Fcf1 PF04900.7 CDJ64379.1 - 7.4e-37 125.5 1.0 7.4e-37 125.5 0.7 2.0 2 0 0 2 2 2 1 Fcf1 PIN PF01850.16 CDJ64379.1 - 0.0083 16.4 0.1 0.89 9.8 0.1 2.4 1 1 0 1 1 1 1 PIN domain Mitochondr_Som1 PF11093.3 CDJ64379.1 - 0.025 14.3 0.4 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial export protein Som1 YqzE PF14038.1 CDJ64379.1 - 7.1 6.4 6.8 15 5.4 4.7 1.6 1 0 0 1 1 1 0 YqzE-like protein DUF1183 PF06682.7 CDJ64380.1 - 0.005 16.4 0.1 0.0058 16.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF601 PF04642.7 CDJ64380.1 - 2.1 7.6 9.4 2.6 7.3 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF601 PP-binding PF00550.20 CDJ64381.1 - 0.0009 19.4 0.1 0.04 14.1 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site EF-hand_9 PF14658.1 CDJ64381.1 - 0.029 14.2 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 CDJ64381.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.2 1 1 0 1 1 1 0 EF-hand domain pair Ank_2 PF12796.2 CDJ64382.1 - 2.2e-62 207.4 9.6 3.2e-19 69.0 0.1 6.5 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ64382.1 - 1.2e-39 132.1 5.5 0.0013 18.4 0.0 11.0 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 CDJ64382.1 - 8.4e-36 121.1 1.2 2.1e-06 27.7 0.0 8.7 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDJ64382.1 - 4.7e-33 112.9 0.5 7e-06 26.4 0.0 8.3 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ64382.1 - 5.8e-30 100.3 0.1 0.026 14.7 0.0 10.7 10 0 0 10 10 10 6 Ankyrin repeat Trep_dent_lipo PF09710.5 CDJ64382.1 - 0.76 8.3 2.3 1.2 7.6 1.6 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) TFIIA PF03153.8 CDJ64382.1 - 1.6 8.5 24.5 0.44 10.4 2.9 2.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Form_Nir_trans PF01226.12 CDJ64384.1 - 7.8e-06 24.9 2.7 8.6e-06 24.8 1.9 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter 5_nucleotid_C PF02872.13 CDJ64385.1 - 1.5e-34 119.2 0.0 3e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CDJ64385.1 - 0.00041 19.8 0.2 0.0045 16.4 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Neogenin_C PF06583.7 CDJ64385.1 - 0.032 13.8 0.2 0.067 12.7 0.1 1.5 2 0 0 2 2 2 0 Neogenin C-terminus F-box-like PF12937.2 CDJ64386.1 - 2.1e-05 24.1 0.9 8.5e-05 22.2 0.7 2.1 1 0 0 1 1 1 1 F-box-like DUF342 PF03961.8 CDJ64386.1 - 0.19 10.1 3.9 0.35 9.2 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Flu_B_NS1 PF02942.9 CDJ64386.1 - 0.38 9.6 0.6 0.7 8.7 0.4 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) FA_desaturase PF00487.19 CDJ64387.1 - 5.2e-11 42.4 13.9 5.2e-11 42.4 9.6 4.0 2 1 1 4 4 4 1 Fatty acid desaturase Pes-10 PF07149.6 CDJ64387.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Pes-10 CLAG PF03805.8 CDJ64390.1 - 5.3e-07 27.4 0.0 1.4e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Cytoadherence-linked asexual protein RPW8 PF05659.6 CDJ64390.1 - 0.013 15.0 0.2 0.21 11.0 0.1 2.6 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Clathrin_bdg PF15045.1 CDJ64390.1 - 0.022 14.2 0.1 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking AMA-1 PF02430.10 CDJ64391.1 - 8.2e-17 61.2 4.5 3.2e-13 49.4 0.4 3.0 3 0 0 3 3 3 2 Apical membrane antigen 1 EGF_2 PF07974.8 CDJ64391.1 - 2.1e-16 59.7 199.1 0.00078 19.5 8.0 11.7 11 0 0 11 11 11 8 EGF-like domain hEGF PF12661.2 CDJ64391.1 - 0.00021 21.1 10.7 0.00061 19.6 2.0 10.4 9 0 0 9 9 9 4 Human growth factor-like EGF EGF PF00008.22 CDJ64391.1 - 0.0024 17.7 5.6 0.0024 17.7 3.9 11.3 12 0 0 12 12 12 6 EGF-like domain DUF3496 PF12001.3 CDJ64391.1 - 0.2 11.8 0.1 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DUF2217 PF10265.4 CDJ64392.1 - 0.16 10.7 6.6 0.19 10.4 4.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Pox_A12 PF04651.8 CDJ64392.1 - 2.5 8.1 8.4 4.4 7.3 5.8 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Ribosomal_S4 PF00163.14 CDJ64393.1 - 2.7e-16 59.7 1.0 2.7e-16 59.7 0.7 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain FA_desaturase PF00487.19 CDJ64393.1 - 0.023 14.1 0.2 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Glyco_trans_2_3 PF13632.1 CDJ64393.1 - 0.25 11.0 2.5 0.35 10.5 1.1 1.7 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Corona_S2 PF01601.11 CDJ64393.1 - 5.9 4.8 25.9 8.2 4.3 17.9 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF2518 PF10726.4 CDJ64394.1 - 0.32 10.5 0.0 0.32 10.5 0.0 1.8 2 1 1 3 3 3 0 Protein of function (DUF2518) DUF3801 PF12687.2 CDJ64395.1 - 4.2 6.9 10.2 1.5 8.3 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3801) RsbRD_N PF14361.1 CDJ64396.1 - 0.16 12.4 3.9 0.2 12.0 2.7 1.2 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain AAA_27 PF13514.1 CDJ64396.1 - 0.17 9.4 13.2 0.19 9.4 9.2 1.0 1 0 0 1 1 1 0 AAA domain Herpes_capsid PF06112.6 CDJ64396.1 - 4.1 7.4 8.8 5.4 7.0 6.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Med15 PF09606.5 CDJ64396.1 - 7.3 4.6 14.7 7.7 4.5 10.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal R_equi_Vir PF05526.6 CDJ64396.1 - 7.7 6.1 7.3 9.1 5.8 5.1 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein UCH PF00443.24 CDJ64397.1 - 4.4e-32 111.2 0.0 4.4e-32 111.2 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase OmpH PF03938.9 CDJ64397.1 - 0.012 15.5 1.5 0.012 15.5 1.1 6.4 3 2 0 3 3 3 0 Outer membrane protein (OmpH-like) zf-ribbon_3 PF13248.1 CDJ64397.1 - 7.4 5.9 6.1 21 4.4 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Proteasome PF00227.21 CDJ64398.1 - 5.3e-55 185.6 0.3 7.6e-55 185.1 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDJ64398.1 - 4.9e-13 48.1 0.0 8.5e-13 47.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Herpes_DNAp_acc PF04929.7 CDJ64400.1 - 5.5 5.8 15.5 0.69 8.8 2.2 2.3 1 1 1 2 2 2 0 Herpes DNA replication accessory factor zf-C3HC4 PF00097.20 CDJ64402.1 - 2.2e-05 24.0 11.6 0.00023 20.7 1.0 3.2 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDJ64402.1 - 5.6e-05 23.1 0.6 5.6e-05 23.1 0.4 3.3 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDJ64402.1 - 0.0065 16.4 2.9 0.0065 16.4 2.0 3.6 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 CDJ64402.1 - 3.4 7.3 11.0 1.1 8.9 0.2 3.6 3 0 0 3 3 3 0 Putative transposase DNA-binding domain TMEM164 PF14808.1 CDJ64403.1 - 0.044 12.9 0.1 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 TMEM164 family Activator_LAG-3 PF11498.3 CDJ64403.1 - 0.057 12.1 11.1 0.066 11.9 7.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Yos1 PF08571.5 CDJ64403.1 - 0.78 9.8 2.5 4.2 7.5 0.7 2.3 2 1 0 2 2 2 0 Yos1-like DUF2116 PF09889.4 CDJ64403.1 - 1.5 8.6 4.7 3.1 7.6 3.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) FAM176 PF14851.1 CDJ64404.1 - 9.9 5.8 8.6 84 2.8 4.7 2.4 2 0 0 2 2 2 0 FAM176 family p25-alpha PF05517.7 CDJ64405.1 - 4.3e-41 140.7 2.1 5.4e-41 140.4 1.5 1.0 1 0 0 1 1 1 1 p25-alpha SurA_N PF09312.6 CDJ64405.1 - 0.0033 17.2 0.1 0.0058 16.4 0.1 1.3 1 0 0 1 1 1 1 SurA N-terminal domain Ku_C PF03730.9 CDJ64405.1 - 0.058 13.9 0.1 0.094 13.2 0.1 1.3 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm EF-hand_6 PF13405.1 CDJ64405.1 - 0.068 13.0 0.5 3.2 7.8 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain WD40 PF00400.27 CDJ64406.1 - 1.8e-25 87.8 5.2 2.8e-05 23.8 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_S27e PF01667.12 CDJ64407.1 - 4.4e-14 51.7 0.7 6.3e-14 51.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 Zn_Tnp_IS1 PF03811.8 CDJ64407.1 - 0.15 11.6 0.2 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 InsA N-terminal domain RNA_pol_N PF01194.12 CDJ64408.1 - 9e-32 108.8 0.6 1.1e-31 108.6 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Thioredoxin PF00085.15 CDJ64409.1 - 8.2e-13 47.9 0.1 9.4e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CDJ64409.1 - 0.00031 20.7 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CDJ64409.1 - 0.018 15.2 0.1 0.02 15.0 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CDJ64409.1 - 0.086 12.4 0.0 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF4367 PF14285.1 CDJ64410.1 - 0.068 12.4 0.4 0.93 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) MCR_alpha PF02249.12 CDJ64410.1 - 5.2 7.0 8.3 22 5.0 0.3 2.6 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Med15 PF09606.5 CDJ64410.1 - 5.3 5.1 42.9 7.2 4.6 29.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BPL_N PF09825.4 CDJ64410.1 - 6.7 5.3 9.1 8.9 4.9 6.3 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Ni_hydr_CYTB PF01292.15 CDJ64411.1 - 0.074 12.4 0.1 0.092 12.1 0.1 1.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Pex14_N PF04695.8 CDJ64411.1 - 1.6 8.7 17.4 5.3 7.0 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PDEase_I PF00233.14 CDJ64413.1 - 3.5e-52 177.5 0.0 4.4e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CDJ64413.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 HD domain PDEase_I PF00233.14 CDJ64414.1 - 2.8e-41 141.8 0.5 5.2e-41 140.9 0.3 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ACOX PF01756.14 CDJ64414.1 - 0.0075 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Condensation PF00668.15 CDJ64416.1 - 3.5e-05 22.7 4.8 0.14 10.9 0.2 3.5 4 0 0 4 4 4 2 Condensation domain AATase PF07247.7 CDJ64416.1 - 0.12 10.9 0.3 3.4 6.0 0.0 2.8 4 0 0 4 4 4 0 Alcohol acetyltransferase RHSP PF07999.6 CDJ64417.1 - 0.62 8.5 0.0 1.1 7.7 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon hot spot protein JmjC PF02373.17 CDJ64418.1 - 2.1e-34 118.2 0.6 2.1e-34 118.2 0.4 2.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 CDJ64418.1 - 0.0065 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 jmjN domain Arf PF00025.16 CDJ64419.1 - 2e-17 62.9 0.0 2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Helicase_C PF00271.26 CDJ64421.1 - 4.1e-07 29.7 3.5 8e-07 28.8 0.0 3.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain cNMP_binding PF00027.24 CDJ64422.1 - 1e-46 156.6 0.0 6e-23 80.4 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Surface_antigen PF11054.3 CDJ64423.1 - 2.7e-31 108.8 0.1 6.7e-31 107.5 0.1 1.6 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Ycf1 PF05758.7 CDJ64424.1 - 0.059 11.0 0.6 0.06 11.0 0.4 1.0 1 0 0 1 1 1 0 Ycf1 NPH3 PF03000.9 CDJ64424.1 - 0.089 12.2 1.0 0.1 12.1 0.7 1.1 1 0 0 1 1 1 0 NPH3 family DUF4407 PF14362.1 CDJ64424.1 - 0.45 9.4 7.9 0.5 9.2 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIF_C PF14721.1 CDJ64424.1 - 0.76 10.0 4.5 0.99 9.6 3.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Chromo PF00385.19 CDJ64425.1 - 3.2e-10 39.5 0.0 9.2e-10 38.0 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Claudin_2 PF13903.1 CDJ64425.1 - 0.02 14.5 0.1 0.02 14.5 0.0 7.7 6 2 2 8 8 8 0 PMP-22/EMP/MP20/Claudin tight junction FA_desaturase PF00487.19 CDJ64425.1 - 0.14 11.5 2.6 0.32 10.4 0.0 2.5 2 0 0 2 2 2 0 Fatty acid desaturase Borrelia_P83 PF05262.6 CDJ64428.1 - 0.0031 15.8 69.4 0.0038 15.5 48.1 1.0 1 0 0 1 1 1 1 Borrelia P83/100 protein Dicty_REP PF05086.7 CDJ64428.1 - 0.18 9.5 22.9 0.22 9.2 15.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.11 CDJ64428.1 - 1.3 8.8 27.8 2 8.2 19.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_Rpb1_1 PF04997.7 CDJ64428.1 - 2.3 7.4 30.3 2.5 7.2 21.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 DUF2146 PF10220.4 CDJ64428.1 - 3.8 5.3 31.8 4.3 5.1 22.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CAF-1_p150 PF11600.3 CDJ64428.1 - 4.6 6.5 77.2 6.8 6.0 53.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med5 PF08689.5 CDJ64428.1 - 4.9 4.7 30.0 5.4 4.5 20.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 DUF966 PF06136.8 CDJ64428.1 - 9.1 5.5 35.8 13 5.1 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) HORMA PF02301.13 CDJ64429.1 - 1e-31 110.0 0.0 1.8e-31 109.2 0.0 1.4 1 1 0 1 1 1 1 HORMA domain Ribosomal_60s PF00428.14 CDJ64429.1 - 0.00027 21.2 18.0 0.039 14.3 0.8 2.3 2 0 0 2 2 2 2 60s Acidic ribosomal protein Chorion_2 PF03964.10 CDJ64429.1 - 0.09 13.3 0.1 0.09 13.3 0.1 2.3 2 0 0 2 2 2 0 Chorion family 2 DUF3886 PF13025.1 CDJ64430.1 - 0.018 15.0 4.8 0.018 15.0 3.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) Hrs_helical PF12210.3 CDJ64430.1 - 3.3 8.0 11.4 0.35 11.1 0.1 3.0 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4207 PF13904.1 CDJ64431.1 - 0.0016 17.9 2.6 0.0016 17.9 1.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4207) DUF4557 PF15101.1 CDJ64431.1 - 0.036 13.9 0.9 0.036 13.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) NusB PF01029.13 CDJ64431.1 - 1.2 9.1 4.4 2.4 8.1 0.1 2.1 2 0 0 2 2 2 0 NusB family DOR PF14839.1 CDJ64431.1 - 1.2 8.8 12.6 4 7.1 0.9 2.1 2 0 0 2 2 2 0 DOR family DUF3373 PF11853.3 CDJ64431.1 - 6.6 5.1 8.0 1.3 7.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) APC_CDC26 PF10471.4 CDJ64431.1 - 7.1 7.4 26.0 12 6.7 6.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Spt20 PF12090.3 CDJ64432.1 - 0.11 11.8 0.9 0.16 11.2 0.6 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.8 CDJ64433.1 - 0.0054 16.6 21.1 0.0065 16.4 14.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ING PF12998.2 CDJ64436.1 - 2.6e-06 27.6 3.0 2.6e-06 27.6 2.1 2.6 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Med15 PF09606.5 CDJ64436.1 - 0.023 12.9 66.7 0.031 12.4 46.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Aminotran_5 PF00266.14 CDJ64439.1 - 6.8e-74 248.8 0.0 1.3e-71 241.3 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CDJ64439.1 - 1.4e-05 24.2 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CDJ64439.1 - 0.0051 15.9 0.0 0.01 14.9 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 CDJ64439.1 - 0.018 13.5 0.0 0.031 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DUF725 PF05267.7 CDJ64439.1 - 0.075 12.9 0.7 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Med3 PF11593.3 CDJ64439.1 - 5.4 6.1 10.2 11 5.1 7.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal tRNA-synt_2 PF00152.15 CDJ64440.1 - 1.5e-55 188.3 0.0 4.5e-55 186.7 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CDJ64440.1 - 5.3e-06 26.1 0.0 1.7e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CDJ64440.1 - 0.16 11.1 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Ribosomal_60s PF00428.14 CDJ64440.1 - 0.39 11.1 24.7 0.54 10.6 7.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RPAP3_C PF13877.1 CDJ64441.1 - 9.6e-08 31.8 0.3 3.3e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 Rib_5-P_isom_A PF06026.9 CDJ64442.1 - 2.9e-45 153.6 0.5 7.6e-43 145.8 0.4 2.0 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF330 PF03886.8 CDJ64442.1 - 0.025 13.9 0.3 0.043 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF330) TetR_N PF00440.18 CDJ64442.1 - 0.1 12.2 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family DUF4539 PF15072.1 CDJ64443.1 - 2.2e-10 40.1 0.0 3.2e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SF3b10 PF07189.6 CDJ64445.1 - 3.1e-33 113.4 0.0 4.5e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DNA_ligase_ZBD PF03119.11 CDJ64445.1 - 0.15 11.8 0.2 0.39 10.4 0.1 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain FYDLN_acid PF09538.5 CDJ64445.1 - 0.87 10.1 10.7 1.2 9.7 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ribosomal_60s PF00428.14 CDJ64445.1 - 4.6 7.7 34.4 1e+02 3.3 24.9 1.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein DnaJ PF00226.26 CDJ64446.1 - 0.0021 17.7 0.0 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S7e PF01251.13 CDJ64447.1 - 5.9e-65 218.3 3.6 6.6e-65 218.1 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4208 PF13907.1 CDJ64447.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Alba PF01918.16 CDJ64448.1 - 6.3e-07 28.8 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 CDJ64448.1 - 5.7e-05 22.7 2.7 0.43 10.2 0.1 3.2 2 1 1 3 3 3 3 Rpp20 subunit of nuclear RNase MRP and P He_PIG PF05345.7 CDJ64449.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 Putative Ig domain Dus PF01207.12 CDJ64450.1 - 4.7e-45 153.7 0.1 7.3e-36 123.5 0.1 2.2 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) ABC1 PF03109.11 CDJ64454.1 - 7.8e-15 54.8 0.0 1.2e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 ABC1 family LRR_4 PF12799.2 CDJ64456.1 - 5.8e-09 35.3 6.0 3.4e-07 29.7 0.8 3.2 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CDJ64456.1 - 9.2e-08 31.3 2.0 0.24 11.5 0.1 4.1 3 1 1 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 CDJ64456.1 - 3.9e-07 29.2 3.1 0.53 10.5 0.0 4.8 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CDJ64456.1 - 4.4e-05 23.0 1.8 2 8.9 0.0 4.7 3 1 1 4 4 4 2 Leucine rich repeat LRR_8 PF13855.1 CDJ64456.1 - 0.003 17.2 7.5 0.042 13.6 1.3 3.2 3 1 1 4 4 4 2 Leucine rich repeat DUF3359 PF11839.3 CDJ64456.1 - 0.27 11.5 5.5 0.064 13.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) SIS PF01380.17 CDJ64457.1 - 7.9e-34 116.0 0.1 8.9e-18 64.1 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 CDJ64457.1 - 1.1e-21 77.1 0.0 2.2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CDJ64457.1 - 4e-18 65.3 0.0 8.1e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CDJ64457.1 - 6.2e-15 54.7 0.2 7.9e-13 47.8 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 CDJ64457.1 - 1.7e-07 30.2 0.1 3.2e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UbiA PF01040.13 CDJ64458.1 - 0.056 12.6 7.4 0.1 11.8 5.1 1.4 1 1 0 1 1 1 0 UbiA prenyltransferase family IncA PF04156.9 CDJ64458.1 - 2.8 7.5 4.5 4.9 6.6 3.1 1.3 1 0 0 1 1 1 0 IncA protein Tic20 PF09685.5 CDJ64458.1 - 3 7.8 11.1 2.4 8.1 1.7 2.9 3 0 0 3 3 3 0 Tic20-like protein DUF4233 PF14017.1 CDJ64459.1 - 0.038 13.9 1.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) DctQ PF04290.7 CDJ64459.1 - 1.4 8.6 7.3 39 3.9 4.5 3.0 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component RNA_GG_bind PF10258.4 CDJ64460.1 - 5.3e-22 77.3 0.0 8e-22 76.7 0.0 1.3 1 0 0 1 1 1 1 PHAX RNA-binding domain Peptidase_S64 PF08192.6 CDJ64461.1 - 1.4 7.1 5.7 2.2 6.4 4.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 Vps51 PF08700.6 CDJ64462.1 - 3e-05 23.7 0.0 6.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 CENP-Q PF13094.1 CDJ64463.1 - 0.043 13.8 8.5 0.081 12.9 2.6 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit tRNA-synt_2b PF00587.20 CDJ64464.1 - 2e-27 95.8 0.0 4e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Kinesin PF00225.18 CDJ64465.1 - 3.1e-93 312.1 0.7 6.7e-93 311.0 0.5 1.5 1 0 0 1 1 1 1 Kinesin motor domain Glyco_hydro_35 PF01301.14 CDJ64465.1 - 0.39 10.0 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 DUF4633 PF15464.1 CDJ64466.1 - 0.1 12.4 0.2 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) rve PF00665.21 CDJ64467.1 - 3.7e-12 46.3 0.0 5.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain SNF2_N PF00176.18 CDJ64469.1 - 1.4e-41 142.2 0.0 2e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDJ64469.1 - 3.3e-10 39.6 0.0 7.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDJ64469.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CDJ64469.1 - 0.0022 16.8 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CDJ64469.1 - 0.0031 17.3 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CDJ64469.1 - 0.035 13.0 0.1 0.087 11.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ECH_C PF13766.1 CDJ64470.1 - 8.5e-08 32.3 1.6 2.9e-07 30.6 0.1 2.1 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CDJ64470.1 - 3.7e-07 29.5 0.0 8e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family iPGM_N PF06415.8 CDJ64470.1 - 0.026 13.8 0.1 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 BPG-independent PGAM N-terminus (iPGM_N) RNA_pol_Rpb4 PF03874.11 CDJ64470.1 - 0.06 13.3 0.2 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb4 RPAP3_C PF13877.1 CDJ64470.1 - 0.073 13.0 0.2 21 5.1 0.0 2.8 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 TPR_11 PF13414.1 CDJ64471.1 - 2.3e-12 46.3 6.8 2.3e-12 46.3 4.7 2.0 2 0 0 2 2 1 1 TPR repeat TPR_1 PF00515.23 CDJ64471.1 - 7.5e-09 34.8 9.9 0.00027 20.4 1.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ64471.1 - 1.5e-08 33.8 8.5 0.00042 20.0 1.5 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ64471.1 - 1.5e-06 27.9 6.7 1.5e-06 27.9 4.7 2.4 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ64471.1 - 0.00026 21.5 13.2 0.00026 21.5 9.1 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ64471.1 - 0.00048 20.5 4.8 0.00048 20.5 3.4 5.0 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ64471.1 - 0.004 16.8 2.8 0.24 11.2 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDJ64471.1 - 0.0091 15.8 2.9 0.26 11.1 0.2 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 CDJ64471.1 - 0.012 15.9 11.6 0.012 15.9 8.0 2.8 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ64471.1 - 0.48 10.3 5.2 22 5.1 3.6 2.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ64471.1 - 0.55 10.8 7.0 0.59 10.7 0.7 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ64471.1 - 4.2 7.8 9.6 0.19 12.0 1.3 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ64471.1 - 4.7 7.2 16.2 0.016 15.1 4.4 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat MutL_C PF08676.6 CDJ64472.1 - 8.5e-13 48.1 0.0 8e-10 38.4 0.0 3.6 4 0 0 4 4 4 2 MutL C terminal dimerisation domain HATPase_c PF02518.21 CDJ64472.1 - 4.8e-10 39.1 0.0 9.3e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CDJ64472.1 - 4e-08 33.0 0.0 7.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 CDJ64472.1 - 4.4e-08 32.6 0.0 1.7e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain P5CR_dimer PF14748.1 CDJ64473.1 - 4.7e-38 129.4 0.1 6.4e-38 129.0 0.1 1.2 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation rve PF00665.21 CDJ64475.1 - 4.3e-19 68.7 0.0 1.6e-18 66.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDJ64475.1 - 0.00054 19.3 2.6 0.0011 18.2 1.8 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 CDJ64476.1 - 0.0051 16.1 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3408 PF11888.3 CDJ64479.1 - 3.2 7.6 20.9 0.38 10.6 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF755 PF05501.6 CDJ64480.1 - 0.047 13.7 36.4 0.69 9.9 9.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) ODV-E18 PF10717.4 CDJ64480.1 - 0.45 9.9 0.0 0.45 9.9 0.0 3.6 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Pap_E4 PF02711.9 CDJ64480.1 - 0.69 10.7 15.9 3.3 8.5 1.5 2.4 2 0 0 2 2 2 0 E4 protein Neur_chan_memb PF02932.11 CDJ64480.1 - 1.3 8.8 9.2 2.3 8.0 6.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EphA2_TM PF14575.1 CDJ64480.1 - 1.4 9.3 0.0 1.4 9.3 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF1675 PF07897.6 CDJ64480.1 - 1.6 8.5 13.6 2.5 7.8 9.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Claudin_2 PF13903.1 CDJ64480.1 - 2.3 7.8 14.7 0.057 13.1 2.4 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction WBP-1 PF11669.3 CDJ64480.1 - 3.3 7.8 4.9 12 6.0 3.1 2.3 1 1 0 1 1 1 0 WW domain-binding protein 1 DUF572 PF04502.8 CDJ64480.1 - 4.1 6.5 14.3 5.9 6.0 9.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 CDJ64480.1 - 4.4 4.8 14.8 5.2 4.6 10.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Conotoxin PF02950.12 CDJ64480.1 - 6.6 7.6 11.5 9.5 7.1 0.1 3.4 3 0 0 3 3 3 0 Conotoxin ORC6 PF05460.8 CDJ64480.1 - 8.4 5.3 16.3 11 4.9 11.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SR-25 PF10500.4 CDJ64481.1 - 0.0027 17.2 30.7 0.0027 17.2 21.3 3.0 1 1 2 3 3 3 1 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDJ64481.1 - 1.7 6.7 57.9 2 6.5 40.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ64481.1 - 2.2 6.3 67.8 2.6 6.1 47.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 CDJ64481.1 - 3.9 5.6 56.6 4.7 5.3 39.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4647 PF15504.1 CDJ64481.1 - 5.6 5.7 43.5 7.1 5.3 30.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) TFIIF_alpha PF05793.7 CDJ64481.1 - 6.3 5.0 40.4 7.6 4.7 28.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Shadoo PF14999.1 CDJ64482.1 - 0.0021 17.8 3.0 0.0031 17.3 2.1 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective CDK2AP PF09806.4 CDJ64482.1 - 0.12 12.6 1.0 0.13 12.5 0.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDJ64482.1 - 0.95 9.9 13.9 0.51 10.7 7.7 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Gluconate_2-dh3 PF13618.1 CDJ64482.1 - 2.2 8.4 7.0 4 7.5 4.8 1.5 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF4604 PF15377.1 CDJ64483.1 - 1.9 8.6 14.4 0.87 9.7 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) FKBP_C PF00254.23 CDJ64484.1 - 2.1e-33 114.1 0.0 3.6e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Porin_4 PF13609.1 CDJ64484.1 - 0.0015 18.0 0.8 0.0026 17.3 0.6 1.4 1 1 0 1 1 1 1 Gram-negative porin TPR_11 PF13414.1 CDJ64484.1 - 0.06 13.0 3.8 0.11 12.1 2.6 1.4 1 0 0 1 1 1 0 TPR repeat PrcB_C PF14343.1 CDJ64484.1 - 0.16 11.7 0.1 0.16 11.7 0.1 1.7 2 0 0 2 2 2 0 PrcB C-terminal PP-binding_2 PF14573.1 CDJ64485.1 - 1.6e-21 76.0 1.0 2.4e-21 75.5 0.1 1.7 2 0 0 2 2 2 1 Acyl-carrier Otopetrin PF03189.8 CDJ64485.1 - 1.9 7.3 5.7 4.8 6.0 4.0 1.7 1 0 0 1 1 1 0 Otopetrin Abhydrolase_5 PF12695.2 CDJ64486.1 - 5.9e-16 58.5 0.1 9.1e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ64486.1 - 1.5e-14 54.4 0.0 2.4e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDJ64486.1 - 2e-07 30.7 0.1 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 CDJ64486.1 - 1.2e-05 23.9 0.1 0.00043 18.8 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 CDJ64486.1 - 0.0002 20.8 1.1 0.0014 18.0 0.4 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 CDJ64486.1 - 0.00045 19.5 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 CDJ64486.1 - 0.00047 19.7 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 CDJ64486.1 - 0.0049 16.4 0.1 0.007 15.9 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 CDJ64486.1 - 0.015 14.8 0.2 0.033 13.7 0.1 1.6 2 0 0 2 2 2 0 Lipase (class 3) MOR2-PAG1_N PF14222.1 CDJ64486.1 - 0.028 13.1 0.5 0.037 12.7 0.4 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Peptidase_S9 PF00326.16 CDJ64486.1 - 0.034 13.3 0.1 4.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CDJ64486.1 - 0.051 13.1 0.1 0.095 12.2 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 CDJ64486.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2217 PF10265.4 CDJ64486.1 - 0.37 9.5 8.4 0.45 9.2 5.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CDJ64486.1 - 0.42 8.8 10.6 0.49 8.6 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 CDJ64486.1 - 1.2 7.1 14.9 1.4 6.8 10.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Secretin_N_2 PF07655.8 CDJ64486.1 - 3.1 8.2 23.4 4.9 7.6 16.2 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Apt1 PF10351.4 CDJ64486.1 - 6.3 5.5 11.0 8.2 5.1 7.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PIG-S PF10510.4 CDJ64487.1 - 4.7e-07 28.8 4.0 0.015 13.9 0.2 4.0 4 0 0 4 4 4 3 Phosphatidylinositol-glycan biosynthesis class S protein MFS_1 PF07690.11 CDJ64488.1 - 3.1e-12 45.8 27.5 3.1e-12 45.8 19.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0060 PF02694.10 CDJ64488.1 - 0.0017 18.3 3.1 0.0017 18.3 2.2 3.3 3 1 1 4 4 4 1 Uncharacterised BCR, YnfA/UPF0060 family OAD_gamma PF04277.8 CDJ64488.1 - 8.4 6.8 19.3 2.4 8.6 0.0 3.8 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain CAF-1_p150 PF11600.3 CDJ64490.1 - 0.0025 17.2 21.0 0.0025 17.2 14.6 4.5 3 2 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 CDJ64491.1 - 0.011 14.3 1.3 0.011 14.3 0.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.1 CDJ64491.1 - 0.054 13.8 9.2 0.06 13.7 6.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SAGA-Tad1 PF12767.2 CDJ64491.1 - 0.24 11.0 12.7 0.28 10.8 8.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CAF-1_p150 PF11600.3 CDJ64491.1 - 0.58 9.5 18.0 0.83 8.9 12.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ashwin PF15323.1 CDJ64491.1 - 0.69 9.8 10.4 0.97 9.3 7.2 1.3 1 0 0 1 1 1 0 Developmental protein Corona_nucleoca PF00937.13 CDJ64491.1 - 0.74 8.7 20.0 1.1 8.1 13.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4603 PF15376.1 CDJ64491.1 - 0.79 6.8 16.1 0.94 6.5 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF572 PF04502.8 CDJ64491.1 - 3.2 6.8 14.3 4.4 6.4 9.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Draxin PF15550.1 CDJ64491.1 - 5.3 6.5 10.8 7 6.2 7.5 1.2 1 0 0 1 1 1 0 Draxin Suf PF05843.9 CDJ64491.1 - 7.3 6.2 9.7 9.6 5.8 6.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ64492.1 - 0.00049 18.4 35.0 0.00049 18.4 24.3 3.1 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDJ64492.1 - 0.0031 16.9 32.1 0.0031 16.9 22.3 4.2 3 1 1 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.1 CDJ64492.1 - 0.0071 16.6 8.0 0.0071 16.6 5.5 1.5 2 0 0 2 2 2 1 AAA domain Activator_LAG-3 PF11498.3 CDJ64492.1 - 0.058 12.1 60.0 0.31 9.7 1.3 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 FLO_LFY PF01698.11 CDJ64492.1 - 2 7.1 16.3 3.6 6.3 11.3 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2052 PF09747.4 CDJ64493.1 - 1.5e-23 83.6 76.6 1.2e-11 44.9 22.2 4.4 2 1 2 4 4 4 3 Coiled-coil domain containing protein (DUF2052) Apolipoprotein PF01442.13 CDJ64494.1 - 1.3e-06 28.1 31.9 1.3e-06 28.1 22.1 2.4 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain AAA_23 PF13476.1 CDJ64494.1 - 0.031 14.5 17.5 0.17 12.1 7.7 2.5 2 0 0 2 2 2 0 AAA domain Tweety PF04906.8 CDJ64494.1 - 0.49 8.7 9.0 0.93 7.8 6.2 1.5 1 0 0 1 1 1 0 Tweety DUF2115 PF09888.4 CDJ64494.1 - 3.9 7.5 8.5 1 9.4 3.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) PMI_typeI PF01238.16 CDJ64496.1 - 0.0078 15.2 0.9 0.011 14.7 0.6 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I CDK2AP PF09806.4 CDJ64497.1 - 0.15 12.2 4.9 0.2 11.8 3.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDJ64498.1 - 1.3 9.5 23.8 6 7.3 7.8 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein FUSC-like PF12805.2 CDJ64501.1 - 0.035 13.0 18.3 0.021 13.7 11.6 1.4 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF912 PF06024.7 CDJ64502.1 - 3.2 7.8 5.9 23 5.1 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) InvH PF04741.7 CDJ64505.1 - 0.029 14.2 2.3 0.039 13.7 1.6 1.2 1 0 0 1 1 1 0 InvH outer membrane lipoprotein AATF-Che1 PF13339.1 CDJ64505.1 - 0.039 14.1 2.2 0.063 13.4 1.5 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor PI3K_1B_p101 PF10486.4 CDJ64505.1 - 0.093 10.2 2.3 0.12 9.9 1.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AF-4 PF05110.8 CDJ64505.1 - 0.13 10.1 16.6 0.16 9.7 11.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein APC_CDC26 PF10471.4 CDJ64505.1 - 0.29 11.8 7.1 0.56 10.9 4.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Corona_nucleoca PF00937.13 CDJ64505.1 - 1.1 8.1 6.8 1.5 7.6 4.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Dsh_C PF12316.3 CDJ64505.1 - 2.5 8.1 12.2 0.38 10.8 4.0 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal FliD_N PF02465.13 CDJ64505.1 - 7.4 7.0 14.6 0.11 12.8 5.0 1.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Dehydrin PF00257.14 CDJ64506.1 - 0.011 16.1 1.1 1.2 9.4 0.4 2.1 2 0 0 2 2 2 0 Dehydrin Acetyltransf_1 PF00583.19 CDJ64507.1 - 7.5e-13 48.3 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CDJ64507.1 - 0.00027 21.0 0.0 0.00027 21.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CDJ64507.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDJ64507.1 - 0.0069 16.1 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein BAF1_ABF1 PF04684.8 CDJ64507.1 - 0.0084 15.0 4.8 0.0088 14.9 3.4 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CDJ64507.1 - 0.023 14.0 0.4 0.027 13.8 0.3 1.1 1 0 0 1 1 1 0 Spt20 family Acetyltransf_9 PF13527.1 CDJ64507.1 - 0.16 11.8 2.5 0.67 9.8 0.0 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF788 PF05620.6 CDJ64507.1 - 3 7.6 6.7 4.9 6.9 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF1510 PF07423.6 CDJ64510.1 - 3 7.1 44.3 3.9 6.7 17.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) HTH_30 PF13556.1 CDJ64511.1 - 0.11 12.1 1.5 26 4.4 0.3 3.3 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain cwf18 PF08315.7 CDJ64512.1 - 9.7e-29 100.4 1.6 9.7e-29 100.4 1.1 1.5 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Jnk-SapK_ap_N PF09744.4 CDJ64512.1 - 5.3 7.0 10.0 0.69 9.8 3.9 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF866 PF05907.8 CDJ64513.1 - 7.7e-29 100.2 0.0 8.7e-29 100.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Macoilin PF09726.4 CDJ64514.1 - 0.00076 17.9 28.1 0.0011 17.3 19.5 1.1 1 0 0 1 1 1 1 Transmembrane protein FCSD-flav_bind PF09242.6 CDJ64514.1 - 0.025 14.5 1.7 0.025 14.5 1.2 4.0 4 2 1 5 5 5 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding SGT1 PF07093.6 CDJ64515.1 - 0.0039 15.6 11.8 0.0041 15.5 8.2 1.1 1 0 0 1 1 1 1 SGT1 protein PAT1 PF09770.4 CDJ64515.1 - 0.034 12.3 42.8 0.032 12.4 29.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.10 CDJ64515.1 - 0.2 10.7 20.2 0.21 10.7 14.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4302 PF14135.1 CDJ64515.1 - 0.31 10.3 8.0 0.43 9.9 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4302) Borrelia_P83 PF05262.6 CDJ64515.1 - 0.33 9.1 23.2 0.35 9.0 16.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Macoilin PF09726.4 CDJ64515.1 - 0.7 8.1 31.5 0.89 7.7 21.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 CDJ64515.1 - 2.2 7.3 27.0 2.7 7.1 18.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lipase_GDSL_3 PF14606.1 CDJ64515.1 - 2.3 7.8 7.7 3.9 7.1 5.4 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Band_3_cyto PF07565.8 CDJ64515.1 - 4.2 6.7 18.1 5.8 6.3 12.5 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PP2C PF00481.16 CDJ64516.1 - 4.4e-17 62.3 0.0 5.5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF3439 PF11921.3 CDJ64517.1 - 0.0041 16.8 13.3 0.0076 15.9 9.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 CDJ64517.1 - 0.0053 16.5 16.5 0.0053 16.5 11.4 1.8 2 0 0 2 2 2 1 Mucin-like glycoprotein SSP160 PF06933.6 CDJ64517.1 - 0.0074 14.3 12.4 0.0093 14.0 8.6 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 CDJ64517.1 - 1.2 6.9 3.7 1.6 6.5 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2806 PF10987.3 CDJ64518.1 - 0.11 11.9 1.6 0.16 11.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2806) MMR1 PF08505.5 CDJ64518.1 - 1.5 8.7 15.9 1.9 8.4 11.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.12 CDJ64518.1 - 1.5 7.5 8.3 2.1 7.0 5.7 1.1 1 0 0 1 1 1 0 Presenilin Gag_spuma PF03276.9 CDJ64518.1 - 6.4 4.9 13.6 9.3 4.4 9.4 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF2360 PF10152.4 CDJ64519.1 - 0.16 12.2 3.4 0.16 12.2 2.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-C4H2 PF10146.4 CDJ64519.1 - 0.19 11.7 2.3 0.2 11.6 1.6 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Gag_spuma PF03276.9 CDJ64519.1 - 0.43 8.8 2.6 0.49 8.6 1.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1176 PF06674.6 CDJ64519.1 - 0.58 9.1 4.6 0.6 9.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) T2SM PF04612.7 CDJ64519.1 - 1.2 8.8 4.5 1.7 8.3 3.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M PseudoU_synth_2 PF00849.17 CDJ64522.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 RNA pseudouridylate synthase DUF947 PF06102.7 CDJ64523.1 - 2.4e-12 46.9 22.0 3e-12 46.6 15.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF947) Herpes_US9 PF06072.6 CDJ64523.1 - 0.17 11.7 1.3 0.56 10.0 0.9 1.9 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3752 PF12572.3 CDJ64523.1 - 0.68 10.0 16.6 0.88 9.6 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DUF4407 PF14362.1 CDJ64523.1 - 1.2 7.9 16.6 1.4 7.7 11.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1707 PF08044.6 CDJ64523.1 - 3.1 7.6 7.8 23 4.8 2.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1707) DUF3138 PF11336.3 CDJ64523.1 - 6.9 4.7 8.8 8.2 4.4 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SMC_N PF02463.14 CDJ64524.1 - 1.7e-23 83.0 0.1 3.9e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CDJ64524.1 - 1.7e-15 57.8 6.3 6.3e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDJ64524.1 - 4.5e-06 26.0 0.0 9.7e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CDJ64524.1 - 7e-06 26.2 0.2 1e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CDJ64524.1 - 0.00046 19.3 0.0 0.00066 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 CDJ64524.1 - 0.026 14.8 0.2 0.026 14.8 0.1 3.3 3 2 0 3 3 2 0 ABC transporter SR-25 PF10500.4 CDJ64524.1 - 0.044 13.2 34.5 0.098 12.1 10.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_17 PF13207.1 CDJ64524.1 - 0.058 14.2 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CDJ64524.1 - 0.075 12.4 2.6 4.4 6.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.12 CDJ64524.1 - 0.092 12.5 0.1 0.092 12.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function DUF87 TIP41 PF04176.8 CDJ64524.1 - 0.11 11.7 2.4 0.25 10.5 1.7 1.6 1 0 0 1 1 1 0 TIP41-like family Herpes_env PF01673.13 CDJ64524.1 - 0.17 10.3 6.0 0.32 9.5 4.1 1.4 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein PAP1 PF08601.5 CDJ64524.1 - 7.5 6.1 31.4 3.5 7.2 16.3 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 PARG_cat PF05028.9 CDJ64525.1 - 3.7e-25 88.8 0.0 4.6e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF2523 PF10734.4 CDJ64525.1 - 0.0013 18.8 0.2 0.0019 18.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2523) AKAP_110 PF05716.8 CDJ64525.1 - 0.088 10.7 0.1 0.11 10.4 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) AAA PF00004.24 CDJ64526.1 - 1.5e-09 38.1 0.5 5.6e-05 23.3 0.0 3.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDJ64526.1 - 0.022 14.4 0.0 0.08 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CDJ64526.1 - 0.12 12.5 0.0 0.12 12.5 0.0 5.1 5 1 1 6 6 6 0 AAA domain AAA_17 PF13207.1 CDJ64526.1 - 0.29 11.9 0.0 0.65 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CDJ64526.1 - 1.5 8.4 4.6 12 5.5 3.1 2.2 1 1 0 1 1 1 0 Archaeal ATPase PseudoU_synth_1 PF01416.15 CDJ64527.1 - 7.6e-05 23.0 12.1 0.015 15.7 7.2 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase UPF0233 PF06781.7 CDJ64527.1 - 0.034 13.7 0.4 0.034 13.7 0.3 5.5 6 1 0 6 6 6 0 Uncharacterised protein family (UPF0233) U1snRNP70_N PF12220.3 CDJ64528.1 - 0.2 11.9 20.6 0.55 10.5 3.3 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal EphA2_TM PF14575.1 CDJ64528.1 - 0.24 11.8 13.9 0.19 12.1 0.3 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Daxx PF03344.10 CDJ64528.1 - 0.29 9.5 30.4 0.37 9.2 21.1 1.1 1 0 0 1 1 1 0 Daxx Family SAGA-Tad1 PF12767.2 CDJ64528.1 - 3.2 7.3 34.8 2.8 7.5 16.7 2.1 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Utp14 PF04615.8 CDJ64528.1 - 4.4 5.3 36.0 7 4.6 25.0 1.3 1 0 0 1 1 1 0 Utp14 protein DUF755 PF05501.6 CDJ64528.1 - 5.1 7.1 49.0 0.35 10.9 10.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF755) FtsL PF04999.8 CDJ64528.1 - 6.5 6.5 22.4 1.6 8.4 2.0 2.8 3 0 0 3 3 3 0 Cell division protein FtsL ARGLU PF15346.1 CDJ64528.1 - 6.6 6.4 26.6 3.5 7.4 4.3 2.9 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 Choline_transpo PF04515.7 CDJ64528.1 - 7.5 5.1 9.5 0.43 9.2 0.3 2.6 2 1 0 2 2 2 0 Plasma-membrane choline transporter Apt1 PF10351.4 CDJ64529.1 - 0.035 12.9 1.8 0.032 13.0 1.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain APC_CDC26 PF10471.4 CDJ64529.1 - 4.5 8.0 12.0 2 9.1 1.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3595 PF12166.3 CDJ64530.1 - 0.47 9.2 2.4 0.66 8.7 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF912 PF06024.7 CDJ64530.1 - 0.61 10.1 4.2 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ndc1_Nup PF09531.5 CDJ64531.1 - 0.011 14.1 23.2 0.014 13.8 16.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dapper PF15268.1 CDJ64531.1 - 0.033 13.0 33.1 0.041 12.6 22.9 1.1 1 0 0 1 1 1 0 Dapper Condensin2nSMC PF12422.3 CDJ64531.1 - 0.039 13.6 0.1 5.4 6.7 0.0 2.7 1 1 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Mem_trans PF03547.13 CDJ64531.1 - 0.74 8.0 3.6 0.88 7.7 2.5 1.3 1 0 0 1 1 1 0 Membrane transport protein PAT1 PF09770.4 CDJ64531.1 - 2.3 6.3 81.4 3.7 5.6 56.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Amidase_6 PF12671.2 CDJ64532.1 - 0.31 11.0 3.3 0.38 10.7 2.3 1.0 1 0 0 1 1 1 0 Putative amidase domain Presenilin PF01080.12 CDJ64533.1 - 0.3 9.8 1.8 0.41 9.4 1.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4598 PF15370.1 CDJ64533.1 - 0.85 9.9 3.3 1.8 8.8 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4598) PAP1 PF08601.5 CDJ64533.1 - 9.6 5.7 19.3 0.33 10.5 8.8 1.7 2 0 0 2 2 2 0 Transcription factor PAP1 eIF-5a PF01287.15 CDJ64534.1 - 3.9e-24 84.3 0.1 5.7e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 CDJ64534.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain CYSTM PF12734.2 CDJ64535.1 - 4.7 7.3 7.7 33 4.6 0.0 2.7 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Cpn60_TCP1 PF00118.19 CDJ64536.1 - 8.7e-113 377.5 0.1 6.7e-44 150.3 0.0 3.0 1 1 2 3 3 3 3 TCP-1/cpn60 chaperonin family APG6 PF04111.7 CDJ64538.1 - 0.14 11.1 10.8 0.27 10.2 7.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CDJ64538.1 - 3.4 5.9 6.9 0.7 8.2 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Ndc1_Nup PF09531.5 CDJ64539.1 - 0.12 10.8 15.2 0.14 10.5 10.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Secretin_N_2 PF07655.8 CDJ64539.1 - 0.28 11.5 15.1 0.53 10.7 10.5 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Herpes_UL87 PF03043.9 CDJ64539.1 - 0.65 8.3 3.0 0.76 8.0 2.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF793 PF05633.6 CDJ64539.1 - 1.1 7.9 6.7 1.4 7.6 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Apt1 PF10351.4 CDJ64539.1 - 2.2 7.0 8.7 2.4 6.9 6.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol_viral_N PF00242.12 CDJ64539.1 - 2.4 7.0 16.9 3 6.8 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain vMSA PF00695.14 CDJ64539.1 - 4 6.5 7.1 4.2 6.4 4.6 1.3 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus Macoilin PF09726.4 CDJ64539.1 - 5 5.2 18.2 5.7 5.1 12.6 1.0 1 0 0 1 1 1 0 Transmembrane protein SRP-alpha_N PF04086.8 CDJ64539.1 - 7.6 5.8 9.2 9.9 5.4 6.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF678 PF05077.7 CDJ64541.1 - 0.091 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF678) His_Phos_2 PF00328.17 CDJ64543.1 - 2.2e-05 23.9 0.0 0.13 11.5 0.0 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 CDJ64543.1 - 0.051 13.6 1.8 0.18 11.9 0.1 2.8 3 1 0 3 3 3 0 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 CDJ64544.1 - 2.2e-31 108.9 5.1 7.2e-16 58.1 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64544.1 - 1.2e-14 54.0 0.0 2.8e-08 33.1 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CDJ64544.1 - 6.3 5.4 0.1 9.8 4.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FAST_1 PF06743.10 CDJ64545.1 - 0.021 14.5 1.7 23 4.7 0.0 4.2 3 2 2 5 5 5 0 FAST kinase-like protein, subdomain 1 MAR_sialic_bdg PF10564.4 CDJ64547.1 - 4.2e-35 119.4 28.5 3.5e-13 49.1 2.3 4.3 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat ProRS-C_1 PF09180.6 CDJ64547.1 - 6.2 6.8 8.5 0.42 10.5 0.3 3.2 3 1 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal MAR_sialic_bdg PF10564.4 CDJ64548.1 - 5.6e-37 125.4 30.4 8.7e-15 54.3 2.3 4.1 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat CPSF_A PF03178.10 CDJ64549.1 - 1.5e-16 60.4 0.0 4e-10 39.2 0.0 3.4 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 CDJ64549.1 - 2.3e-10 39.2 0.1 2.3e-10 39.2 0.1 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term SR-25 PF10500.4 CDJ64549.1 - 0.00014 21.3 12.5 0.00014 21.3 8.7 13.0 12 1 1 13 13 13 4 Nuclear RNA-splicing-associated protein Syja_N PF02383.13 CDJ64550.1 - 2.3e-28 98.9 0.1 2.3e-28 98.9 0.0 2.1 2 0 0 2 2 2 1 SacI homology domain Ribosomal_60s PF00428.14 CDJ64550.1 - 0.089 13.2 30.3 0.65 10.4 10.5 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Macoilin PF09726.4 CDJ64550.1 - 0.12 10.5 26.0 0.23 9.6 18.0 1.4 1 1 0 1 1 1 0 Transmembrane protein DNA_pol3_delta2 PF13177.1 CDJ64551.1 - 0.054 13.1 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF4139 PF13598.1 CDJ64551.1 - 2.3 7.4 12.7 4 6.6 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) WD40 PF00400.27 CDJ64552.1 - 3.8e-13 48.7 5.3 0.008 16.0 0.1 5.4 5 1 0 5 5 5 5 WD domain, G-beta repeat MACPF PF01823.14 CDJ64553.1 - 5.6e-38 130.7 0.3 5.6e-38 130.7 0.2 2.5 3 0 0 3 3 3 1 MAC/Perforin domain Baculo_PEP_C PF04513.7 CDJ64553.1 - 0.026 14.3 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3315 PF11776.3 CDJ64555.1 - 0.018 14.5 0.3 0.047 13.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) RIO1 PF01163.17 CDJ64559.1 - 1.6e-30 105.8 0.0 1.6e-17 63.4 0.1 3.0 2 1 0 2 2 2 2 RIO1 family DUF3446 PF11928.3 CDJ64559.1 - 0.018 15.2 3.7 0.018 15.2 2.5 6.2 5 2 1 6 6 6 0 Domain of unknown function (DUF3446) RIO1 PF01163.17 CDJ64560.1 - 1.9e-05 24.0 1.6 2e-05 24.0 0.4 1.5 1 1 1 2 2 2 1 RIO1 family Med15 PF09606.5 CDJ64560.1 - 0.0044 15.3 18.8 0.0052 15.0 13.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDJ64560.1 - 0.0061 16.4 0.1 0.0064 16.4 0.1 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DUF3371 PF11851.3 CDJ64560.1 - 0.018 15.6 6.0 0.024 15.3 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Suf PF05843.9 CDJ64560.1 - 0.038 13.7 6.3 0.046 13.4 4.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ64560.1 - 0.059 12.7 6.7 0.07 12.4 4.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF4557 PF15101.1 CDJ64560.1 - 0.09 12.6 7.7 0.1 12.4 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pex14_N PF04695.8 CDJ64560.1 - 0.2 11.6 7.6 0.28 11.2 5.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 CDJ64560.1 - 0.8 8.4 15.7 0.94 8.2 10.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF719 PF05334.8 CDJ64560.1 - 1.1 9.2 5.2 1.5 8.8 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Pex26 PF07163.7 CDJ64560.1 - 3.9 6.3 5.3 4.7 6.0 3.7 1.1 1 0 0 1 1 1 0 Pex26 protein DUF4175 PF13779.1 CDJ64560.1 - 5.9 4.4 19.5 7.1 4.1 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MDFI PF15316.1 CDJ64563.1 - 0.13 12.2 1.1 0.17 11.8 0.8 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Tox-PL PF15644.1 CDJ64563.1 - 0.2 12.4 2.9 0.29 11.8 2.0 1.2 1 0 0 1 1 1 0 Papain fold toxin 1 FHIPEP PF00771.15 CDJ64563.1 - 0.32 9.2 7.2 0.37 9.0 5.0 1.2 1 0 0 1 1 1 0 FHIPEP family Suf PF05843.9 CDJ64563.1 - 0.4 10.3 2.5 0.49 10.0 1.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ64563.1 - 0.91 9.3 13.9 1.1 9.1 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ64563.1 - 4.3 5.4 15.6 5.1 5.1 10.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD_3 PF13922.1 CDJ64563.1 - 8.2 6.7 7.6 5 7.4 1.3 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Cnd1 PF12717.2 CDJ64565.1 - 6.1e-15 55.5 0.0 1.7e-12 47.5 0.0 3.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 zf-Nse PF11789.3 CDJ64566.1 - 0.0051 16.2 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CAF-1_p150 PF11600.3 CDJ64567.1 - 0.0096 15.3 19.5 0.015 14.7 13.5 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.1 CDJ64567.1 - 0.015 15.6 13.2 0.022 15.0 9.2 1.4 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDJ64567.1 - 0.03 12.5 59.6 0.041 12.0 41.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ64567.1 - 0.045 12.0 43.6 0.051 11.8 30.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Jiraiya PF15038.1 CDJ64567.1 - 0.35 10.2 8.0 0.06 12.7 1.1 2.4 2 0 0 2 2 2 0 Jiraiya SOBP PF15279.1 CDJ64567.1 - 0.51 10.6 19.1 0.67 10.2 13.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF966 PF06136.8 CDJ64567.1 - 1.5 8.1 20.4 2 7.7 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Spc7_N PF15402.1 CDJ64567.1 - 1.6 6.6 20.1 2.2 6.1 13.9 1.3 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 TFIIA PF03153.8 CDJ64567.1 - 2.1 8.1 36.7 2.9 7.6 25.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GbpC PF08363.5 CDJ64567.1 - 4.1 6.5 12.7 6.6 5.8 8.8 1.3 1 0 0 1 1 1 0 Glucan-binding protein C BTV_NS2 PF04514.7 CDJ64567.1 - 5.2 5.8 12.1 7.1 5.3 8.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CemA PF03040.9 CDJ64567.1 - 6.6 6.2 9.8 9.4 5.7 6.8 1.3 1 0 0 1 1 1 0 CemA family Hom_end_hint PF05203.11 CDJ64567.1 - 8.7 6.0 9.8 13 5.4 6.8 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Spt20 PF12090.3 CDJ64570.1 - 7e-06 25.5 1.3 1.3e-05 24.6 0.9 1.4 1 0 0 1 1 1 1 Spt20 family DUF3357 PF11837.3 CDJ64570.1 - 0.011 15.6 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) SR-25 PF10500.4 CDJ64570.1 - 0.016 14.6 0.1 0.016 14.6 0.1 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EphA2_TM PF14575.1 CDJ64570.1 - 0.018 15.4 1.3 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Med3 PF11593.3 CDJ64571.1 - 4.4 6.4 12.9 4.2 6.5 8.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MIP-T3 PF10243.4 CDJ64572.1 - 0.037 12.5 27.7 0.047 12.1 19.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 CDJ64572.1 - 2.4 8.4 14.3 3.3 7.9 9.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_M24 PF00557.19 CDJ64572.1 - 3.2 7.2 7.0 9.8 5.6 1.5 2.4 2 0 0 2 2 2 0 Metallopeptidase family M24 Med15 PF09606.5 CDJ64572.1 - 3.7 5.6 33.5 4.5 5.3 23.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LMBR1 PF04791.11 CDJ64572.1 - 4.6 5.7 8.2 5.8 5.3 5.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM196 PF15265.1 CDJ64572.1 - 6.1 5.9 32.0 8 5.5 22.2 1.1 1 0 0 1 1 1 0 FAM196 family Macoilin PF09726.4 CDJ64572.1 - 8 4.5 25.3 11 4.1 17.5 1.1 1 0 0 1 1 1 0 Transmembrane protein SMAP PF15477.1 CDJ64574.1 - 4.9e-15 55.5 0.0 4.9e-15 55.5 0.0 4.4 4 2 0 4 4 4 1 Small acidic protein family FHA PF00498.21 CDJ64574.1 - 9.3e-15 54.5 0.0 1.6e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain SR-25 PF10500.4 CDJ64574.1 - 0.0022 17.4 40.5 0.0022 17.4 28.0 3.4 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF677 PF05055.7 CDJ64574.1 - 0.03 13.0 1.0 0.047 12.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) vMSA PF00695.14 CDJ64574.1 - 0.13 11.4 0.2 0.27 10.3 0.1 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Cwf_Cwc_15 PF04889.7 CDJ64574.1 - 8.3 6.0 25.9 8.5 6.0 13.9 2.7 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Activator_LAG-3 PF11498.3 CDJ64575.1 - 0.00054 18.8 0.4 0.0011 17.7 0.3 1.5 1 0 0 1 1 1 1 Transcriptional activator LAG-3 FliO PF04347.8 CDJ64575.1 - 0.13 12.2 2.3 1.2 9.1 1.6 2.9 1 1 0 1 1 1 0 Flagellar biosynthesis protein, FliO FSIP1 PF15554.1 CDJ64576.1 - 0.046 12.5 5.9 0.075 11.8 4.1 1.3 1 0 0 1 1 1 0 FSIP1 family Peptidase_S15 PF02129.13 CDJ64577.1 - 0.0031 16.9 18.7 0.0038 16.6 13.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Paf1 PF03985.8 CDJ64577.1 - 0.4 9.3 25.5 0.42 9.2 17.7 1.2 1 0 0 1 1 1 0 Paf1 CAF-1_p150 PF11600.3 CDJ64577.1 - 0.6 9.4 33.5 0.73 9.1 23.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDJ64577.1 - 0.92 8.7 59.1 1.2 8.4 41.0 1.0 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 CDJ64577.1 - 1.6 8.5 23.7 2.1 8.1 16.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4175 PF13779.1 CDJ64577.1 - 1.6 6.3 64.0 1.6 6.3 44.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pox_Ag35 PF03286.9 CDJ64577.1 - 1.7 8.1 16.7 2 7.9 11.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.7 CDJ64577.1 - 1.9 7.5 17.0 1.8 7.6 11.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PPP4R2 PF09184.6 CDJ64577.1 - 2 7.8 20.0 2.4 7.6 13.9 1.1 1 0 0 1 1 1 0 PPP4R2 AAA_23 PF13476.1 CDJ64577.1 - 2 8.6 31.5 2.5 8.3 21.8 1.2 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.7 CDJ64577.1 - 3 6.3 31.1 3.5 6.1 21.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR3 PF03666.8 CDJ64577.1 - 3.3 6.1 21.5 3.4 6.0 14.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.3 CDJ64577.1 - 3.7 6.1 22.5 4 6.0 15.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Raftlin PF15250.1 CDJ64577.1 - 3.8 5.9 24.1 4.4 5.7 16.7 1.1 1 0 0 1 1 1 0 Raftlin Cellulose_synt PF03552.9 CDJ64577.1 - 3.9 5.6 14.6 4.2 5.5 10.1 1.0 1 0 0 1 1 1 0 Cellulose synthase LicD PF04991.8 CDJ64577.1 - 4.3 7.4 6.3 4.4 7.3 4.4 1.2 1 0 0 1 1 1 0 LicD family FAM91_C PF14648.1 CDJ64577.1 - 4.3 6.0 12.8 4.3 6.0 8.9 1.1 1 0 0 1 1 1 0 FAM91 C-terminus PCEMA1 PF07418.6 CDJ64577.1 - 4.8 6.4 12.3 5.5 6.2 8.5 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 CDC45 PF02724.9 CDJ64577.1 - 5 5.0 24.7 5.6 4.8 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 CDJ64577.1 - 5.3 5.5 21.1 5.6 5.4 14.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDJ64577.1 - 6 4.4 25.4 6.4 4.3 17.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF2217 PF10265.4 CDJ64577.1 - 7.2 5.2 15.6 9.6 4.8 10.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Zip PF02535.17 CDJ64577.1 - 8.6 5.2 11.6 8.5 5.2 8.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.7 CDJ64577.1 - 9.1 4.9 13.6 9.9 4.7 9.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PsaN PF05479.6 CDJ64578.1 - 0.13 12.2 6.4 0.54 10.2 0.1 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Fungal_trans PF04082.13 CDJ64578.1 - 2.2 7.0 8.0 0.18 10.6 2.1 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain Glyco_tranf_2_4 PF13704.1 CDJ64578.1 - 7.2 6.9 8.4 1.1 9.5 0.5 2.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 PAT1 PF09770.4 CDJ64578.1 - 8.1 4.5 65.8 11 4.1 45.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydro_lipase PF04083.11 CDJ64580.1 - 8.1e-07 28.3 0.0 8.6e-06 25.0 0.0 2.7 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region BAF1_ABF1 PF04684.8 CDJ64581.1 - 0.0014 17.5 2.6 0.0014 17.5 1.8 5.8 6 0 0 6 6 6 2 BAF1 / ABF1 chromatin reorganising factor Serglycin PF04360.7 CDJ64581.1 - 0.0029 17.3 2.7 0.0084 15.8 1.9 1.7 1 0 0 1 1 1 1 Serglycin Spt20 PF12090.3 CDJ64581.1 - 0.47 9.7 18.3 3.6 6.8 0.7 3.4 3 0 0 3 3 3 0 Spt20 family Pox_Ag35 PF03286.9 CDJ64581.1 - 4.4 6.7 15.9 5.5 6.4 4.7 3.4 3 0 0 3 3 3 0 Pox virus Ag35 surface protein SR-25 PF10500.4 CDJ64582.1 - 0.0022 17.4 11.7 0.0035 16.8 8.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ64582.1 - 0.012 14.9 8.6 0.017 14.5 5.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Vpu PF00558.14 CDJ64582.1 - 0.15 11.6 4.2 0.25 10.9 2.9 1.3 1 0 0 1 1 1 0 Vpu protein Hex_IIIa PF02455.11 CDJ64582.1 - 0.75 8.4 5.8 0.95 8.0 4.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF1168 PF06658.7 CDJ64582.1 - 5.7 6.4 15.4 0.024 14.1 4.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) ETRAMP PF09716.5 CDJ64582.1 - 6.5 6.7 5.4 1.3 9.0 0.1 2.3 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Nop25 PF09805.4 CDJ64582.1 - 7.7 6.5 15.5 0.28 11.2 5.7 1.9 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Spt5_N PF11942.3 CDJ64582.1 - 8.3 7.1 12.7 19 5.9 8.8 1.7 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SOBP PF15279.1 CDJ64583.1 - 0.78 10.0 9.7 0.84 9.9 2.6 2.5 2 0 0 2 2 2 0 Sine oculis-binding protein PGA2 PF07543.7 CDJ64583.1 - 4.2 7.1 9.7 1.2 8.9 2.1 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 NPV_P10 PF05531.7 CDJ64584.1 - 4.3 7.6 13.1 5 7.4 0.1 4.9 4 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein PDZ_2 PF13180.1 CDJ64585.1 - 0.05 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Tom22 PF04281.8 CDJ64587.1 - 0.00018 21.0 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 RskA PF10099.4 CDJ64587.1 - 0.032 13.9 1.9 0.035 13.8 1.3 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Nol1_Nop2_Fmu PF01189.12 CDJ64588.1 - 2e-27 96.2 1.1 1.7e-19 70.3 0.0 4.2 3 2 0 3 3 3 2 NOL1/NOP2/sun family TFIIA PF03153.8 CDJ64588.1 - 6 6.6 41.3 1.3 8.8 10.9 3.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Herpes_UL87 PF03043.9 CDJ64588.1 - 7 4.9 6.6 0.42 8.9 0.7 1.7 2 0 0 2 2 2 0 Herpesvirus UL87 family Tubulin PF00091.20 CDJ64589.1 - 3.7e-68 229.5 0.0 4.9e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDJ64589.1 - 1.8e-51 173.4 0.3 7.6e-51 171.4 0.1 1.9 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CDJ64589.1 - 0.03 13.7 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain GHMP_kinases_N PF00288.21 CDJ64590.1 - 0.036 14.1 3.5 0.043 13.8 2.4 1.1 1 0 0 1 1 1 0 GHMP kinases N terminal domain Chorion_2 PF03964.10 CDJ64590.1 - 0.067 13.7 7.4 0.087 13.3 5.1 1.3 1 1 0 1 1 1 0 Chorion family 2 Shadoo PF14999.1 CDJ64590.1 - 0.09 12.6 2.8 0.084 12.7 2.0 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective BAF1_ABF1 PF04684.8 CDJ64590.1 - 0.7 8.6 2.3 0.72 8.6 1.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CSTF2_hinge PF14327.1 CDJ64591.1 - 0.00076 19.5 3.0 0.0031 17.5 2.1 2.0 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 DNA_III_psi PF03603.8 CDJ64591.1 - 0.19 11.5 2.5 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III psi subunit DUF1635 PF07795.6 CDJ64591.1 - 0.35 10.2 5.0 1.6 8.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) tRNA-synt_2b PF00587.20 CDJ64592.1 - 1.1e-24 86.9 0.0 3.2e-24 85.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_C1 PF00112.18 CDJ64592.1 - 2.7e-15 56.8 7.1 5.4e-12 46.0 0.3 2.8 2 1 1 3 3 3 2 Papain family cysteine protease CathepsinC_exc PF08773.6 CDJ64592.1 - 1.4e-07 31.7 1.6 0.019 15.1 0.0 3.3 1 1 2 3 3 3 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 CDJ64592.1 - 0.046 12.2 0.2 0.079 11.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase C1-like family Sec3-PIP2_bind PF15277.1 CDJ64593.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.5 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Thioredoxin PF00085.15 CDJ64595.1 - 8.6e-25 86.4 0.0 1e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CDJ64595.1 - 5.9e-07 29.6 0.1 1e-05 25.7 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CDJ64595.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like ERp29_N PF07912.8 CDJ64595.1 - 0.00074 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_6 PF13848.1 CDJ64595.1 - 0.0032 17.2 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 CDJ64595.1 - 0.0084 15.6 0.1 0.012 15.1 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 CDJ64595.1 - 0.0098 15.9 0.0 0.12 12.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 CDJ64595.1 - 0.12 12.0 0.1 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family Amino_oxidase PF01593.19 CDJ64596.1 - 5.1e-40 137.8 11.5 1.8e-33 116.3 0.1 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase zf-CW PF07496.10 CDJ64596.1 - 1.5e-32 111.0 38.9 2.3e-11 43.2 5.2 3.7 3 0 0 3 3 3 3 CW-type Zinc Finger NAD_binding_8 PF13450.1 CDJ64596.1 - 5e-06 26.4 5.3 5e-06 26.4 3.6 3.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDJ64596.1 - 0.00025 20.9 0.3 0.00077 19.3 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDJ64596.1 - 0.012 14.7 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 CDJ64596.1 - 0.39 11.1 2.2 0.38 11.1 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDJ64596.1 - 2 8.3 10.2 0.12 12.3 0.4 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Dynamin_M PF01031.15 CDJ64597.1 - 1.9e-89 299.3 0.0 4.8e-87 291.4 0.0 2.2 1 1 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CDJ64597.1 - 2.5e-52 177.0 0.0 7e-52 175.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CDJ64597.1 - 4.2e-31 106.7 2.9 4.5e-31 106.5 0.7 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CDJ64597.1 - 6.9e-05 22.7 0.0 0.0002 21.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CDJ64597.1 - 0.018 15.0 0.9 0.5 10.3 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 CDJ64597.1 - 0.028 14.9 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein TRAM_LAG1_CLN8 PF03798.11 CDJ64599.1 - 1.2e-24 87.0 19.3 1.6e-24 86.5 13.4 1.2 1 0 0 1 1 1 1 TLC domain Pkinase PF00069.20 CDJ64601.1 - 1.5e-41 142.3 0.0 1.9e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64601.1 - 2.2e-23 82.6 0.0 2.7e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDJ64601.1 - 4.6e-05 23.2 0.0 0.011 15.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CDJ64601.1 - 0.027 13.2 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC1 PF03109.11 CDJ64601.1 - 0.066 13.1 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 ABC1 family Kinase-like PF14531.1 CDJ64601.1 - 0.083 11.8 0.0 2.5 6.9 0.0 2.6 3 0 0 3 3 3 0 Kinase-like Nucleoporin_FG PF13634.1 CDJ64602.1 - 1.7e-13 50.7 192.6 0.0079 16.4 26.2 6.8 1 1 3 4 4 4 3 Nucleoporin FG repeat region Nsp1_C PF05064.8 CDJ64602.1 - 4.7e-13 48.8 3.4 4.7e-13 48.8 2.3 2.3 1 1 2 3 3 3 1 Nsp1-like C-terminal region DUF1664 PF07889.7 CDJ64602.1 - 0.043 13.6 6.9 0.64 9.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliD_C PF07195.7 CDJ64602.1 - 0.2 10.8 2.7 0.34 10.1 0.7 2.2 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus AAA_13 PF13166.1 CDJ64602.1 - 0.45 8.9 5.0 0.55 8.6 3.5 1.0 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 CDJ64602.1 - 4.6 7.0 8.6 2.8 7.7 4.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus rve PF00665.21 CDJ64603.1 - 0.0026 17.8 0.1 0.0075 16.3 0.0 1.7 2 1 0 2 2 2 1 Integrase core domain DUF1564 PF07600.6 CDJ64603.1 - 0.05 12.9 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Aconitase PF00330.15 CDJ64604.1 - 3e-112 375.4 0.0 4.6e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CDJ64604.1 - 5.8e-41 139.6 0.0 1.2e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain TSP_1 PF00090.14 CDJ64608.1 - 0.002 18.1 8.4 0.002 18.1 5.8 3.1 2 1 0 2 2 2 1 Thrombospondin type 1 domain Septin PF00735.13 CDJ64608.1 - 0.13 11.2 0.0 0.32 9.9 0.0 1.7 2 0 0 2 2 2 0 Septin TSP_1 PF00090.14 CDJ64609.1 - 1.8e-06 27.9 33.1 0.0044 17.0 0.7 6.4 5 1 0 5 5 5 3 Thrombospondin type 1 domain Corona_nucleoca PF00937.13 CDJ64609.1 - 4.7 6.0 4.4 7.8 5.3 3.0 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein G-patch_2 PF12656.2 CDJ64610.1 - 8.7e-12 44.7 0.0 8.7e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site DUF3685 PF12452.3 CDJ64610.1 - 0.082 12.0 1.4 0.13 11.4 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) Rz1 PF06085.6 CDJ64612.1 - 0.037 13.4 1.5 0.11 11.9 1.1 1.8 1 0 0 1 1 1 0 Lipoprotein Rz1 precursor FAM101 PF15068.1 CDJ64612.1 - 0.1 12.0 0.4 0.19 11.1 0.2 1.5 1 1 0 1 1 1 0 FAM101 family Chorion_2 PF03964.10 CDJ64612.1 - 2.6 8.6 11.9 5.6 7.5 8.3 1.5 1 1 0 1 1 1 0 Chorion family 2 PAT1 PF09770.4 CDJ64612.1 - 4.1 5.5 13.1 4.5 5.3 9.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDJ64613.1 - 1.2e-06 28.1 60.4 0.00029 20.2 6.4 3.7 3 0 0 3 3 3 2 SprA-related family BAF1_ABF1 PF04684.8 CDJ64613.1 - 0.0015 17.4 11.5 0.0015 17.4 8.0 4.3 4 1 1 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 CDJ64613.1 - 0.0072 16.0 1.5 0.0072 16.0 1.1 3.4 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) DUF737 PF05300.6 CDJ64613.1 - 0.012 15.5 4.6 0.012 15.5 3.2 4.9 3 2 0 3 3 3 0 Protein of unknown function (DUF737) Spore_YhcN_YlaJ PF09580.5 CDJ64613.1 - 0.071 13.2 10.1 0.51 10.4 0.1 2.6 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3357 PF11837.3 CDJ64614.1 - 0.011 15.5 1.3 0.017 14.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) PulG PF11773.3 CDJ64614.1 - 0.057 13.1 4.1 0.084 12.6 2.8 1.2 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin CDK5_activator PF03261.10 CDJ64614.1 - 3.4 6.9 5.1 4.1 6.6 3.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.8 CDJ64614.1 - 3.5 7.4 17.3 4 7.2 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PSK PF06404.7 CDJ64614.1 - 7.3 7.4 6.9 1.3 9.8 0.9 2.2 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) OSCP PF00213.13 CDJ64615.1 - 1.1e-15 57.8 3.1 1.1e-15 57.8 2.2 1.9 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit Sporozoite_P67 PF05642.6 CDJ64615.1 - 0.091 10.6 2.1 0.12 10.2 1.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TAF4 PF05236.9 CDJ64615.1 - 0.17 11.1 6.4 0.17 11.1 3.9 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Totivirus_coat PF05518.6 CDJ64615.1 - 0.34 8.6 6.7 0.54 8.0 4.6 1.2 1 0 0 1 1 1 0 Totivirus coat protein Lin-8 PF03353.10 CDJ64615.1 - 0.65 9.2 6.2 0.92 8.7 4.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4557 PF15101.1 CDJ64615.1 - 0.92 9.3 6.2 1.5 8.6 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Trs65 PF12735.2 CDJ64615.1 - 3.9 6.7 9.0 5.3 6.2 6.3 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF1117 PF06547.7 CDJ64615.1 - 6 6.9 10.8 1.5 8.9 5.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Ribosomal_60s PF00428.14 CDJ64616.1 - 0.029 14.7 2.9 0.029 14.7 2.0 9.0 4 2 3 7 7 7 0 60s Acidic ribosomal protein Tmemb_9 PF05434.6 CDJ64616.1 - 0.32 10.7 1.2 0.56 9.9 0.8 1.4 1 0 0 1 1 1 0 TMEM9 SpoVAD PF07451.6 CDJ64617.1 - 0.087 11.2 3.6 0.1 11.0 2.5 1.0 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) MSP1_C PF07462.6 CDJ64617.1 - 0.42 8.9 7.6 0.44 8.8 5.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Suf PF05843.9 CDJ64617.1 - 1.4 8.5 8.0 1.7 8.2 5.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BaxI_1 PF12811.2 CDJ64617.1 - 1.8 7.6 5.9 2.8 7.0 4.1 1.3 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF4544 PF15077.1 CDJ64617.1 - 3.7 6.9 6.2 2.6 7.5 3.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4544) EURL PF06937.6 CDJ64617.1 - 8.2 5.7 9.3 9.8 5.4 6.5 1.0 1 0 0 1 1 1 0 EURL protein Rep_4 PF05797.6 CDJ64618.1 - 0.04 12.6 0.6 0.061 12.0 0.3 1.4 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF4131 PF13567.1 CDJ64618.1 - 0.44 9.9 0.0 0.44 9.9 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) HEAT_EZ PF13513.1 CDJ64618.1 - 1.2 9.6 17.2 3.2 8.3 8.4 3.3 3 1 0 3 3 3 0 HEAT-like repeat DUF755 PF05501.6 CDJ64619.1 - 0.0064 16.5 13.0 0.0064 16.5 9.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF755) SR-25 PF10500.4 CDJ64619.1 - 0.023 14.1 18.5 0.043 13.2 12.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.6 CDJ64619.1 - 3.8 5.4 6.1 5.4 4.9 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAD_binding_4 PF07993.7 CDJ64620.1 - 6.8e-53 179.1 0.0 1.3e-52 178.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 CDJ64620.1 - 7e-43 146.3 0.1 2.2e-41 141.4 0.0 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 CDJ64620.1 - 7.3e-33 113.8 0.2 3.9e-31 108.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Sulfotransfer_1 PF00685.22 CDJ64620.1 - 5.9e-17 61.7 0.0 1.3e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CDJ64620.1 - 2.1e-14 54.7 0.0 5.9e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Sulfotransferase family PP-binding PF00550.20 CDJ64620.1 - 1.1e-11 44.8 0.0 4.4e-11 42.8 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CDJ64620.1 - 8.5e-10 38.4 0.0 7.6e-08 32.0 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDJ64620.1 - 0.03 13.0 0.0 0.12 11.0 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 CDJ64620.1 - 0.057 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF1331 PF07048.6 CDJ64620.1 - 0.1 12.1 0.1 0.75 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Fer4_6 PF12837.2 CDJ64620.1 - 5.2 7.1 8.8 7.2 6.6 0.3 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.2 CDJ64620.1 - 8.1 7.0 7.3 6.3 7.4 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain IMCp PF12314.3 CDJ64621.1 - 4.1e-28 97.3 60.3 7.9e-28 96.4 28.1 5.0 2 2 2 4 4 4 2 Inner membrane complex protein IMCp PF12314.3 CDJ64622.1 - 5.3e-33 113.0 92.6 9.2e-19 67.3 20.1 4.8 1 1 4 5 5 5 4 Inner membrane complex protein LSM PF01423.17 CDJ64623.1 - 4.2e-14 51.8 0.8 6.7e-14 51.1 0.6 1.3 1 0 0 1 1 1 1 LSM domain RRM_6 PF14259.1 CDJ64624.1 - 9e-09 35.1 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ64624.1 - 8.3e-08 31.7 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ64624.1 - 3e-05 23.7 0.0 4.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AT_hook PF02178.14 CDJ64625.1 - 0.63 9.9 6.5 1.7 8.5 4.5 1.8 1 0 0 1 1 1 0 AT hook motif Nucleoside_tran PF01733.13 CDJ64626.1 - 3.5e-15 55.9 9.4 3.5e-15 55.9 6.5 1.5 2 0 0 2 2 2 1 Nucleoside transporter NTP_transf_2 PF01909.18 CDJ64627.1 - 0.12 12.6 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain Dicty_REP PF05086.7 CDJ64627.1 - 8.5 3.9 0.6 15 3.1 0.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EGF_3 PF12947.2 CDJ64628.1 - 1.4e-05 24.8 56.0 0.00058 19.7 9.2 5.8 5 1 0 5 5 5 4 EGF domain cEGF PF12662.2 CDJ64628.1 - 0.00034 20.1 37.0 0.13 11.8 3.2 5.6 4 1 0 4 4 4 3 Complement Clr-like EGF-like Lamp PF01299.12 CDJ64628.1 - 0.0012 18.0 0.1 0.0012 18.0 0.1 2.3 2 0 0 2 2 2 1 Lysosome-associated membrane glycoprotein (Lamp) FXa_inhibition PF14670.1 CDJ64628.1 - 0.0075 16.3 73.7 0.014 15.4 5.7 6.1 5 1 1 6 6 6 4 Coagulation Factor Xa inhibitory site DDHD PF02862.12 CDJ64628.1 - 0.039 13.7 2.3 0.055 13.2 1.6 1.1 1 0 0 1 1 1 0 DDHD domain EGF_CA PF07645.10 CDJ64628.1 - 0.089 12.7 63.6 0.5 10.3 9.2 5.8 5 0 0 5 5 5 0 Calcium-binding EGF domain SAGA-Tad1 PF12767.2 CDJ64630.1 - 0.049 13.3 8.8 0.069 12.8 6.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Daxx PF03344.10 CDJ64630.1 - 0.29 9.5 24.2 0.33 9.4 16.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF444 PF04285.7 CDJ64630.1 - 0.3 9.6 13.7 0.41 9.2 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) BTV_NS2 PF04514.7 CDJ64630.1 - 0.36 9.6 11.2 0.48 9.2 7.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 CDJ64630.1 - 0.79 8.5 17.1 1.1 8.0 11.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Draxin PF15550.1 CDJ64630.1 - 1.3 8.5 11.5 1.9 8.0 8.0 1.1 1 0 0 1 1 1 0 Draxin TFIIF_alpha PF05793.7 CDJ64630.1 - 3.4 5.9 25.8 4.6 5.4 17.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 CDJ64630.1 - 5 4.9 26.2 7.6 4.3 18.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 CDJ64630.1 - 5 6.4 26.4 9.2 5.5 18.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 CDJ64630.1 - 9.2 4.7 14.5 12 4.4 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macro PF01661.16 CDJ64634.1 - 4.1e-09 36.3 0.0 5.4e-06 26.3 0.0 3.0 2 0 0 2 2 2 2 Macro domain Spt20 PF12090.3 CDJ64634.1 - 0.055 12.8 0.3 0.055 12.8 0.2 3.9 4 0 0 4 4 4 0 Spt20 family CENP-L PF13092.1 CDJ64634.1 - 0.34 10.6 2.8 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 DUF775 PF05603.7 CDJ64636.1 - 7.5e-21 74.5 0.4 1.2e-17 64.0 0.3 3.2 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Corona_nucleoca PF00937.13 CDJ64636.1 - 0.059 12.3 1.0 0.069 12.0 0.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CDK2AP PF09806.4 CDJ64636.1 - 0.15 12.2 2.3 0.21 11.8 1.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Herpes_capsid PF06112.6 CDJ64636.1 - 5.7 6.9 15.6 8.4 6.4 10.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RAB3GAP2_N PF14655.1 CDJ64638.1 - 0.054 12.4 9.1 0.11 11.4 6.3 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4446 PF14584.1 CDJ64638.1 - 1.9 8.3 6.3 3.3 7.5 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SCF PF02404.10 CDJ64639.1 - 1 8.5 3.2 1 8.4 0.8 2.0 2 0 0 2 2 2 0 Stem cell factor Collagen PF01391.13 CDJ64640.1 - 3.2e-14 52.2 75.2 4.9e-08 32.4 22.7 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Ribosomal_60s PF00428.14 CDJ64641.1 - 0.0051 17.1 6.2 0.0077 16.6 4.3 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein RskA PF10099.4 CDJ64641.1 - 0.0099 15.6 5.5 0.012 15.3 3.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TP_methylase PF00590.15 CDJ64641.1 - 0.1 12.2 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Chorion_2 PF03964.10 CDJ64641.1 - 0.27 11.8 4.9 0.39 11.2 3.4 1.3 1 0 0 1 1 1 0 Chorion family 2 PAT1 PF09770.4 CDJ64641.1 - 2.1 6.4 11.2 2.2 6.4 7.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PepSY_2 PF13670.1 CDJ64641.1 - 2.9 7.8 8.4 4.5 7.2 5.8 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain AAA PF00004.24 CDJ64642.1 - 4.1e-46 156.4 0.0 1.2e-34 119.3 0.0 3.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDJ64642.1 - 1.7e-06 27.7 0.2 0.054 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDJ64642.1 - 6.7e-06 26.9 0.0 0.15 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CDJ64642.1 - 3.6e-05 23.2 0.1 0.093 12.1 0.0 3.9 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 CDJ64642.1 - 0.00049 20.4 0.2 0.82 9.9 0.0 3.4 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 CDJ64642.1 - 0.00068 19.7 0.5 1.2 9.3 0.0 3.9 3 0 0 3 3 2 1 RNA helicase AAA_22 PF13401.1 CDJ64642.1 - 0.00074 19.6 11.3 0.0081 16.3 0.2 5.3 3 2 1 4 4 3 1 AAA domain CDC48_N PF02359.13 CDJ64642.1 - 0.00078 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.8 CDJ64642.1 - 0.00089 18.0 0.0 0.11 11.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 CDJ64642.1 - 0.0034 17.2 0.0 0.82 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CDJ64642.1 - 0.013 15.2 0.1 6 6.4 0.0 3.7 3 1 0 3 3 3 0 Archaeal ATPase UPF0079 PF02367.12 CDJ64642.1 - 0.014 14.9 0.1 9.4 5.8 0.0 2.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 CDJ64642.1 - 0.11 11.5 0.2 0.35 9.9 0.0 1.9 2 0 0 2 2 2 0 KaiC DUF2052 PF09747.4 CDJ64644.1 - 2.2 8.2 15.0 3.4 7.5 10.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Med19 PF10278.4 CDJ64644.1 - 2.2 7.9 7.7 4 7.0 5.4 1.4 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Macoilin PF09726.4 CDJ64644.1 - 3 6.0 40.1 4.1 5.5 27.8 1.1 1 0 0 1 1 1 0 Transmembrane protein RskA PF10099.4 CDJ64644.1 - 7.7 6.2 25.1 0.073 12.7 3.2 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Mito_carr PF00153.22 CDJ64646.1 - 9.5e-39 131.0 0.0 9.9e-17 60.4 0.0 4.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ELL PF10390.4 CDJ64646.1 - 8.8 5.4 6.2 6.9 5.8 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL SR-25 PF10500.4 CDJ64647.1 - 0.0015 18.0 1.3 0.0015 18.0 0.9 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ64647.1 - 0.18 11.1 2.7 0.17 11.2 0.2 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TT_ORF1 PF02956.9 CDJ64648.1 - 3 6.2 5.5 4.1 5.7 3.8 1.1 1 0 0 1 1 1 0 TT viral orf 1 Gly-zipper_OmpA PF13436.1 CDJ64648.1 - 8.3 6.0 28.9 1.1 8.9 0.3 3.5 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain MORN PF02493.15 CDJ64649.1 - 3.2e-39 130.3 44.1 3.6e-06 26.3 0.7 7.2 7 0 0 7 7 7 7 MORN repeat Dehalogenase PF13486.1 CDJ64651.1 - 0.012 15.1 0.2 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Reductive dehalogenase subunit RskA PF10099.4 CDJ64651.1 - 0.064 12.9 16.0 1 9.0 7.0 3.0 2 1 0 2 2 2 0 Anti-sigma-K factor rskA CDK2AP PF09806.4 CDJ64651.1 - 2.6 8.2 8.2 4.9 7.3 0.1 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3306 PF11748.3 CDJ64651.1 - 5.3 7.7 9.3 1.8 9.2 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) IncA PF04156.9 CDJ64652.1 - 0.00041 20.0 4.1 0.00041 20.0 2.8 2.1 2 0 0 2 2 2 1 IncA protein Suf PF05843.9 CDJ64652.1 - 0.086 12.5 24.6 0.32 10.6 3.3 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SR-25 PF10500.4 CDJ64652.1 - 0.087 12.2 32.2 0.21 11.0 0.6 2.4 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDJ64652.1 - 0.45 8.6 56.5 0.053 11.7 13.2 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 CDJ64652.1 - 7.1 6.2 24.7 3.3 7.3 3.7 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit CRAL_TRIO_2 PF13716.1 CDJ64653.1 - 2.7e-05 24.1 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ctr PF04145.10 CDJ64653.1 - 0.0031 17.5 0.9 0.0045 17.0 0.6 1.3 1 0 0 1 1 1 1 Ctr copper transporter family PEX11 PF05648.9 CDJ64653.1 - 0.0046 16.2 3.4 0.0081 15.4 2.4 1.4 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spt20 PF12090.3 CDJ64653.1 - 0.088 12.1 5.4 0.1 11.9 3.8 1.2 1 0 0 1 1 1 0 Spt20 family CemA PF03040.9 CDJ64653.1 - 0.2 11.2 2.1 0.27 10.7 1.4 1.2 1 0 0 1 1 1 0 CemA family Nucleoside_tran PF01733.13 CDJ64653.1 - 0.76 8.8 2.5 1 8.4 1.7 1.2 1 0 0 1 1 1 0 Nucleoside transporter DUF4557 PF15101.1 CDJ64653.1 - 1.1 9.1 10.9 1.6 8.5 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2347 PF09804.4 CDJ64653.1 - 6.2 6.0 7.7 12 5.0 5.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Med3 PF11593.3 CDJ64654.1 - 0.48 9.6 18.6 0.53 9.4 12.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-B_box PF00643.19 CDJ64655.1 - 0.00012 21.8 8.1 0.00012 21.8 5.6 3.7 3 1 1 4 4 4 2 B-box zinc finger zf-C3HC4_3 PF13920.1 CDJ64655.1 - 0.0008 19.0 16.5 0.0008 19.0 11.4 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FA_desaturase PF00487.19 CDJ64656.1 - 1.7e-24 86.6 23.3 1.7e-24 86.6 16.2 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.5 CDJ64656.1 - 8.7e-10 37.6 0.3 2.4e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) Spt20 PF12090.3 CDJ64656.1 - 0.028 13.7 0.9 2.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDJ64656.1 - 0.58 9.1 15.7 0.81 8.6 6.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein PBP1_TM PF14812.1 CDJ64656.1 - 1.4 9.3 9.2 17 5.8 4.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pex14_N PF04695.8 CDJ64656.1 - 3.6 7.6 11.9 0.22 11.5 1.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RNA_pol_Rpc4 PF05132.9 CDJ64656.1 - 4.8 7.1 8.9 13 5.7 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 CAP_N PF01213.14 CDJ64656.1 - 5.1 6.2 12.7 8 5.6 8.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MSP1_C PF07462.6 CDJ64656.1 - 9.9 4.4 13.7 15 3.8 9.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Form-deh_trans PF09163.6 CDJ64657.1 - 0.0035 16.8 1.1 0.008 15.6 0.7 1.5 1 0 0 1 1 1 1 Formate dehydrogenase N, transmembrane AAA_23 PF13476.1 CDJ64658.1 - 1 9.6 25.3 0.17 12.2 5.0 2.2 2 0 0 2 2 2 0 AAA domain SpoIIP PF07454.6 CDJ64658.1 - 4.8 6.2 22.7 1.6 7.8 2.9 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Gly-zipper_OmpA PF13436.1 CDJ64659.1 - 0.0035 16.9 2.1 0.0043 16.7 1.5 1.1 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain RskA PF10099.4 CDJ64659.1 - 0.0045 16.7 2.1 0.0051 16.5 1.5 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA UCR_Fe-S_N PF10399.4 CDJ64659.1 - 0.0089 15.1 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pex14_N PF04695.8 CDJ64659.1 - 0.012 15.6 2.9 0.014 15.3 2.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ETRAMP PF09716.5 CDJ64659.1 - 0.016 15.1 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PHD_3 PF13922.1 CDJ64659.1 - 0.017 15.3 7.0 0.024 14.8 4.8 1.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Spt20 PF12090.3 CDJ64659.1 - 0.033 13.5 1.2 0.031 13.6 0.8 1.1 1 0 0 1 1 1 0 Spt20 family She9_MDM33 PF05546.6 CDJ64659.1 - 0.035 13.6 0.3 0.045 13.3 0.2 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family ABC_tran_2 PF12848.2 CDJ64659.1 - 0.045 13.5 7.3 0.052 13.3 5.1 1.1 1 0 0 1 1 1 0 ABC transporter OAD_gamma PF04277.8 CDJ64659.1 - 0.046 14.0 2.8 0.057 13.8 1.9 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PsbQ PF05757.6 CDJ64659.1 - 0.061 12.7 4.2 0.072 12.5 2.9 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF2722 PF10846.3 CDJ64659.1 - 0.065 12.2 3.5 0.068 12.2 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) LZ_Tnp_IS66 PF13007.2 CDJ64659.1 - 0.068 13.8 9.2 0.099 13.3 6.4 1.3 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain UPF0560 PF10577.4 CDJ64659.1 - 0.071 11.3 4.1 0.082 11.1 2.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TMEM51 PF15345.1 CDJ64659.1 - 0.09 12.4 1.4 0.1 12.2 0.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 MRP-S31 PF15433.1 CDJ64659.1 - 0.099 12.0 3.3 0.11 11.9 2.3 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PEX11 PF05648.9 CDJ64659.1 - 0.1 11.8 0.4 0.12 11.6 0.3 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) RAB3GAP2_N PF14655.1 CDJ64659.1 - 0.12 11.3 3.3 0.13 11.2 2.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PsbW PF07123.7 CDJ64659.1 - 0.14 12.2 1.7 0.15 12.1 1.2 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Med15 PF09606.5 CDJ64659.1 - 0.15 10.2 13.7 0.16 10.1 9.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 CDJ64659.1 - 0.16 11.8 5.8 0.18 11.6 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FCP1_C PF09309.5 CDJ64659.1 - 0.16 11.2 3.5 0.19 11.0 2.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal PsaN PF05479.6 CDJ64659.1 - 0.21 11.5 3.1 0.25 11.3 2.1 1.1 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF3138 PF11336.3 CDJ64659.1 - 0.44 8.6 6.4 0.44 8.6 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TAF4 PF05236.9 CDJ64659.1 - 0.52 9.5 7.4 0.59 9.3 5.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BRF1 PF07741.8 CDJ64659.1 - 0.53 10.5 4.7 0.64 10.2 3.2 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain P_C PF06640.6 CDJ64659.1 - 0.67 9.9 4.8 0.73 9.7 3.3 1.1 1 0 0 1 1 1 0 P protein C-terminus Activator_LAG-3 PF11498.3 CDJ64659.1 - 0.93 8.1 14.5 1 8.0 10.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DAG_kinase_N PF14513.1 CDJ64659.1 - 0.98 9.6 4.4 1.5 9.0 3.1 1.4 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF788 PF05620.6 CDJ64659.1 - 1.4 8.7 4.1 2.2 8.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Calpain_inhib PF00748.14 CDJ64659.1 - 3.1 8.1 6.5 3.9 7.8 4.5 1.1 1 0 0 1 1 1 0 Calpain inhibitor TSA PF03249.8 CDJ64659.1 - 5.3 5.4 15.8 7.3 5.0 10.9 1.3 1 0 0 1 1 1 0 Type specific antigen E_Pc_C PF06752.7 CDJ64659.1 - 9.6 5.6 14.7 11 5.4 10.2 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus TFIIA PF03153.8 CDJ64660.1 - 0.00079 19.4 23.2 0.0012 18.8 16.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 CDJ64660.1 - 0.0028 15.4 8.3 0.0036 15.1 5.8 1.0 1 0 0 1 1 1 1 Ycf1 SAPS PF04499.10 CDJ64660.1 - 0.075 11.6 7.5 0.09 11.4 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CDJ64660.1 - 0.09 10.4 11.1 0.13 9.9 7.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cyto_heme_lyase PF01265.12 CDJ64660.1 - 0.12 11.9 19.7 0.18 11.3 13.7 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF2413 PF10310.4 CDJ64660.1 - 0.27 9.9 17.7 0.39 9.4 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Otopetrin PF03189.8 CDJ64660.1 - 0.3 10.0 7.5 0.46 9.4 5.2 1.2 1 0 0 1 1 1 0 Otopetrin DUF3530 PF12048.3 CDJ64660.1 - 0.92 8.4 22.6 0.04 12.8 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) DUF1510 PF07423.6 CDJ64660.1 - 3.3 7.0 19.2 4.5 6.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3807 PF12720.2 CDJ64660.1 - 3.3 7.8 22.5 4.9 7.2 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Pal1 PF08316.6 CDJ64660.1 - 3.4 8.1 8.5 3.7 8.0 1.5 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein Oleosin PF01277.12 CDJ64660.1 - 3.6 7.1 7.5 14 5.2 2.2 2.2 2 0 0 2 2 2 0 Oleosin Pex16 PF08610.5 CDJ64660.1 - 3.6 6.4 15.5 4 6.3 1.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) RIC3 PF15361.1 CDJ64660.1 - 3.9 7.7 19.3 4.9 7.3 7.1 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Alg14 PF08660.6 CDJ64660.1 - 4.5 7.2 10.3 3.1 7.7 0.3 2.1 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Baculo_PP31 PF05311.6 CDJ64660.1 - 4.7 6.4 17.5 4.5 6.4 6.1 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Gti1_Pac2 PF09729.4 CDJ64660.1 - 4.8 7.0 13.9 11 5.8 0.1 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Pex14_N PF04695.8 CDJ64660.1 - 5.4 7.0 30.1 3.4 7.7 10.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2782 PF11191.3 CDJ64660.1 - 5.5 7.0 8.9 5.3 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) Spore_coat_CotO PF14153.1 CDJ64660.1 - 5.8 6.3 27.2 0.66 9.3 2.0 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Dala_Dala_lig_N PF01820.16 CDJ64660.1 - 6.4 7.1 9.0 11 6.4 0.2 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus TCP PF03634.8 CDJ64660.1 - 7.8 6.8 25.5 6.3 7.1 0.9 2.1 2 0 0 2 2 2 0 TCP family transcription factor DUF3260 PF11658.3 CDJ64660.1 - 8.3 4.4 14.2 4.1 5.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) PAT1 PF09770.4 CDJ64660.1 - 9 4.3 43.3 2.2 6.4 7.5 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HlyD_2 PF12700.2 CDJ64660.1 - 9.9 5.2 18.0 6.8 5.7 6.0 2.0 2 0 0 2 2 2 0 HlyD family secretion protein Pkinase PF00069.20 CDJ64661.1 - 6.5e-25 87.7 0.1 7.2e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64661.1 - 2.4e-14 53.0 0.1 2.7e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase His_binding PF02098.11 CDJ64661.1 - 0.046 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Tick histamine binding protein DUF4207 PF13904.1 CDJ64662.1 - 0.053 12.8 20.4 0.088 12.1 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DivIC PF04977.10 CDJ64662.1 - 0.12 11.8 6.3 0.3 10.5 4.3 1.7 1 0 0 1 1 1 0 Septum formation initiator Suf PF05843.9 CDJ64662.1 - 1.1 8.9 12.9 1.8 8.2 8.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1754 PF08555.5 CDJ64662.1 - 1.1 9.8 11.6 2.8 8.5 8.1 1.7 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) PAT1 PF09770.4 CDJ64662.1 - 1.9 6.6 18.5 2.8 6.0 12.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rtf2 PF04641.7 CDJ64662.1 - 8.9 5.4 16.2 0.17 11.0 6.3 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger Ndc1_Nup PF09531.5 CDJ64664.1 - 0.00074 18.0 5.2 0.00085 17.8 3.6 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF788 PF05620.6 CDJ64664.1 - 0.065 13.0 0.5 0.18 11.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Baculo_PP31 PF05311.6 CDJ64664.1 - 0.76 8.9 7.2 0.29 10.3 1.2 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF4512 PF14975.1 CDJ64664.1 - 1.6 9.6 4.9 0.75 10.6 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) NTP_transf_5 PF14907.1 CDJ64664.1 - 2.8 7.2 7.7 1.3 8.2 0.6 2.3 2 1 0 2 2 2 0 Uncharacterised nucleotidyltransferase DUF966 PF06136.8 CDJ64664.1 - 4.1 6.7 9.2 5.3 6.3 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RAB3GAP2_N PF14655.1 CDJ64664.1 - 5.8 5.7 8.7 0.4 9.6 2.3 1.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DivIC PF04977.10 CDJ64664.1 - 7.9 6.0 12.6 1.3 8.5 3.8 2.3 2 1 0 2 2 2 0 Septum formation initiator Peptidase_S64 PF08192.6 CDJ64664.1 - 9.6 4.3 7.8 11 4.1 5.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Na_sulph_symp PF00939.14 CDJ64665.1 - 5.2e-30 104.7 13.6 1.8e-15 56.7 5.0 2.0 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CDJ64665.1 - 2.7e-08 32.8 26.2 0.00019 20.1 3.5 3.2 3 0 0 3 3 3 3 Citrate transporter DUF1071 PF06378.6 CDJ64665.1 - 0.26 10.4 0.7 0.64 9.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) BAF1_ABF1 PF04684.8 CDJ64665.1 - 0.93 8.2 8.7 0.54 9.0 4.3 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor YajC PF02699.10 CDJ64665.1 - 3 7.6 5.5 0.39 10.4 0.1 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit Pkinase PF00069.20 CDJ64667.1 - 1.6e-64 217.5 0.0 2e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64667.1 - 9.1e-30 103.5 0.0 1.2e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ64667.1 - 1.5e-06 27.4 0.0 1e-05 24.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CDJ64667.1 - 0.0012 17.9 0.0 0.0037 16.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDJ64667.1 - 0.023 14.4 0.0 0.36 10.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.15 CDJ64667.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase YrbL-PhoP_reg PF10707.4 CDJ64667.1 - 0.037 13.3 0.1 0.065 12.5 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RNase_HII PF01351.13 CDJ64668.1 - 2e-49 167.9 0.0 2e-45 154.8 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII PASTA PF03793.14 CDJ64668.1 - 0.12 11.9 0.0 0.48 10.1 0.0 2.0 1 0 0 1 1 1 0 PASTA domain Aminotran_4 PF01063.14 CDJ64669.1 - 2.9e-10 40.0 0.0 6.3e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class IV Zip PF02535.17 CDJ64669.1 - 0.13 11.2 0.2 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PBP1_TM PF14812.1 CDJ64669.1 - 1.6 9.0 5.4 14 6.0 1.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ctr PF04145.10 CDJ64669.1 - 3.5 7.6 4.8 5.4 7.0 1.8 2.4 2 0 0 2 2 2 0 Ctr copper transporter family Pex16 PF08610.5 CDJ64669.1 - 5.2 5.9 13.1 11 4.9 9.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Suf PF05843.9 CDJ64669.1 - 9.1 5.9 10.1 20 4.8 7.0 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Arena_glycoprot PF00798.13 CDJ64670.1 - 3.3 6.0 7.5 5.2 5.3 5.2 1.3 1 0 0 1 1 1 0 Arenavirus glycoprotein E1-E2_ATPase PF00122.15 CDJ64672.1 - 1.1e-16 60.5 0.0 2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CDJ64672.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Guanylate_cyc PF00211.15 CDJ64673.1 - 3.5e-80 267.6 0.8 1.9e-43 147.9 0.1 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HAD PF12710.2 CDJ64673.1 - 1.3e-10 41.7 0.0 2.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDJ64673.1 - 8.6e-09 36.1 0.0 3.1e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDJ64673.1 - 2.2e-05 24.1 0.0 0.00051 19.7 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Amidase PF01425.16 CDJ64674.1 - 0.00047 19.1 0.8 1 8.1 0.0 3.1 3 1 1 4 4 4 2 Amidase SAC3_GANP PF03399.11 CDJ64675.1 - 7.9e-17 61.4 0.1 2.6e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family OmpH PF03938.9 CDJ64675.1 - 0.008 16.1 46.3 0.12 12.3 0.0 6.0 4 2 0 4 4 4 1 Outer membrane protein (OmpH-like) DUF2938 PF11158.3 CDJ64676.1 - 0.52 9.6 5.7 0.085 12.1 1.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2938) DUF2208 PF09973.4 CDJ64676.1 - 0.7 9.0 3.3 0.45 9.7 1.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) TauE PF01925.14 CDJ64677.1 - 1.6e-22 80.1 23.5 3.1e-11 43.1 0.1 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF4328 PF14219.1 CDJ64677.1 - 0.00024 20.4 0.2 0.00083 18.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) GPI2 PF06432.6 CDJ64677.1 - 1.3 8.3 10.4 0.092 12.0 0.2 2.8 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase Macoilin PF09726.4 CDJ64678.1 - 0.0017 16.7 6.7 0.0017 16.7 4.7 2.3 2 0 0 2 2 2 1 Transmembrane protein Citrate_synt PF00285.16 CDJ64679.1 - 1.1e-74 251.2 0.0 1.1e-36 126.3 0.0 2.0 1 1 1 2 2 2 2 Citrate synthase WD40 PF00400.27 CDJ64680.1 - 1.1e-55 183.6 35.8 1.4e-12 46.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 CDJ64680.1 - 0.00022 21.4 1.0 0.024 14.9 0.0 3.7 3 1 0 3 3 3 1 PQQ-like domain Nup160 PF11715.3 CDJ64680.1 - 0.017 13.2 19.5 0.81 7.7 0.3 5.4 1 1 3 4 4 4 0 Nucleoporin Nup120/160 tRNA-synt_1 PF00133.17 CDJ64681.1 - 1e-80 271.4 0.0 2.1e-40 138.3 0.0 5.5 5 1 0 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CDJ64681.1 - 2.8e-10 39.4 0.4 3.8e-06 25.8 0.0 3.8 4 0 0 4 4 4 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CDJ64681.1 - 0.041 13.1 0.2 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Kei1 PF08552.6 CDJ64681.1 - 0.066 12.8 0.5 0.37 10.4 0.0 2.3 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2012 PF09430.5 CDJ64682.1 - 4.8e-10 39.3 0.0 7.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) IncA PF04156.9 CDJ64682.1 - 0.0036 16.9 1.1 0.0061 16.1 0.8 1.3 1 0 0 1 1 1 1 IncA protein OTU PF02338.14 CDJ64683.1 - 7.9e-12 45.8 0.0 2e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CDJ64683.1 - 7.5e-05 22.2 0.1 0.00087 18.7 0.1 2.2 1 1 1 2 2 2 1 Peptidase C65 Otubain VWA PF00092.23 CDJ64684.1 - 3.6e-45 153.8 0.0 5.1e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 CDJ64684.1 - 2.9e-24 84.9 68.0 1.1e-07 31.8 1.6 7.2 6 1 0 6 6 6 6 Thrombospondin type 1 domain VWA_2 PF13519.1 CDJ64684.1 - 4.4e-17 62.7 0.3 7.6e-17 61.9 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 CDJ64684.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 CDJ64684.1 - 0.0096 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain NRN1 PF15056.1 CDJ64684.1 - 0.25 11.3 8.4 0.19 11.6 0.2 3.3 2 1 1 3 3 3 0 Neuritin protein family Pro_isomerase PF00160.16 CDJ64685.1 - 9.7e-34 116.8 0.0 2.9e-33 115.2 0.0 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SpoIIIAH PF12685.2 CDJ64685.1 - 0.008 15.6 0.0 0.008 15.6 0.0 7.8 6 2 1 7 7 7 2 SpoIIIAH-like protein Trs65 PF12735.2 CDJ64685.1 - 1.8 7.8 0.0 1.8 7.8 0.0 6.8 6 2 1 8 8 8 0 TRAPP trafficking subunit Trs65 S1 PF00575.18 CDJ64687.1 - 0.0065 16.5 0.0 0.022 14.8 0.0 1.8 1 1 0 1 1 1 1 S1 RNA binding domain Plasmodium_Vir PF05795.6 CDJ64687.1 - 5.2 6.1 5.2 13 4.8 3.6 1.7 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RNA_pol_Rpb1_2 PF00623.15 CDJ64687.1 - 5.3 6.9 8.0 0.6 10.0 2.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 2 DUF3446 PF11928.3 CDJ64688.1 - 2.2 8.5 56.2 2.1 8.6 4.8 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3446) Kinesin PF00225.18 CDJ64689.1 - 5.9e-61 206.0 11.0 5.9e-61 206.0 7.6 2.3 3 0 0 3 3 3 1 Kinesin motor domain Suf PF05843.9 CDJ64690.1 - 0.21 11.2 9.4 0.017 14.8 3.2 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 CDJ64690.1 - 1 9.1 18.3 0.02 14.7 7.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Spt20 PF12090.3 CDJ64690.1 - 2.2 7.5 10.2 3.9 6.7 7.0 1.3 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDJ64690.1 - 6.8 5.6 16.4 11 4.9 11.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein MIP-T3 PF10243.4 CDJ64691.1 - 0.0072 14.8 28.7 0.0086 14.5 19.9 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF4647 PF15504.1 CDJ64691.1 - 0.97 8.2 29.7 1.4 7.7 20.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Ycf1 PF05758.7 CDJ64691.1 - 1 7.0 17.3 1.1 6.8 12.0 1.0 1 0 0 1 1 1 0 Ycf1 Utp14 PF04615.8 CDJ64691.1 - 1 7.4 27.7 1.1 7.2 19.2 1.1 1 0 0 1 1 1 0 Utp14 protein TFIIF_alpha PF05793.7 CDJ64691.1 - 1.1 7.5 17.5 1.4 7.1 12.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAT1 PF09770.4 CDJ64691.1 - 1.1 7.3 80.5 1.3 7.1 55.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.1 CDJ64691.1 - 1.2 8.3 26.9 1.6 7.9 18.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RskA PF10099.4 CDJ64691.1 - 1.4 8.6 31.1 3 7.5 11.6 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF1183 PF06682.7 CDJ64691.1 - 3.2 7.2 23.6 5.1 6.5 16.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Mitofilin PF09731.4 CDJ64691.1 - 4 5.9 28.8 5 5.6 20.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.2 CDJ64691.1 - 5.8 4.4 34.6 7.2 4.1 24.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VID27 PF08553.5 CDJ64691.1 - 6.6 4.8 13.8 8.3 4.4 9.6 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Asp-B-Hydro_N PF05279.6 CDJ64691.1 - 7 6.4 17.3 8.4 6.1 12.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF966 PF06136.8 CDJ64691.1 - 7.9 5.7 27.0 9.4 5.5 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Cellulose_synt PF03552.9 CDJ64691.1 - 8.3 4.5 5.4 9 4.4 3.7 1.2 1 0 0 1 1 1 0 Cellulose synthase SR-25 PF10500.4 CDJ64692.1 - 0.076 12.4 32.9 0.18 11.2 6.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.4 CDJ64692.1 - 0.49 9.1 5.1 0.56 8.9 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain LSM PF01423.17 CDJ64693.1 - 5.6e-14 51.4 0.3 6.8e-14 51.1 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CDJ64693.1 - 0.00037 20.3 0.5 0.004 17.0 0.2 1.9 1 1 1 2 2 2 1 Ataxin 2 SM domain DUF2642 PF10842.3 CDJ64693.1 - 0.17 11.4 0.4 0.26 10.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) AIP3 PF03915.8 CDJ64694.1 - 0.037 12.9 21.4 0.058 12.3 14.8 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Herpes_UL87 PF03043.9 CDJ64694.1 - 0.13 10.5 5.7 0.18 10.1 3.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family YjgP_YjgQ PF03739.9 CDJ64694.1 - 0.17 10.6 6.5 0.21 10.2 4.5 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Med15 PF09606.5 CDJ64694.1 - 0.18 9.9 70.3 0.31 9.1 48.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DFP PF04127.10 CDJ64694.1 - 0.19 11.3 7.3 0.33 10.5 5.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF2228 PF10228.4 CDJ64694.1 - 0.41 10.1 10.8 0.68 9.4 7.5 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) APG6 PF04111.7 CDJ64694.1 - 0.73 8.8 32.0 1.6 7.7 22.2 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CDJ64694.1 - 0.76 7.5 27.9 1.8 6.2 7.6 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 CDJ64694.1 - 0.93 8.3 38.1 0.02 13.8 21.8 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 CDJ64694.1 - 1.6 5.9 41.0 2.6 5.2 28.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RNA_pol_Rpb1_1 PF04997.7 CDJ64694.1 - 1.6 7.8 16.6 6.1 6.0 8.5 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 Exonuc_VII_L PF02601.10 CDJ64694.1 - 1.7 7.7 28.2 0.091 11.9 15.3 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF966 PF06136.8 CDJ64694.1 - 1.8 7.9 16.4 0.76 9.1 8.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DNA_topoisoIV PF00521.15 CDJ64694.1 - 3.3 6.4 17.0 5.3 5.7 11.8 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Spc7 PF08317.6 CDJ64694.1 - 4.2 5.9 28.3 7.8 5.0 19.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 CDJ64694.1 - 5.9 6.6 47.6 0.22 11.3 24.8 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Peptidase_S64 PF08192.6 CDJ64694.1 - 6.2 5.0 17.3 10 4.2 12.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 Occludin_ELL PF07303.8 CDJ64694.1 - 9.8 6.9 26.2 4.9 7.9 3.6 2.6 2 0 0 2 2 2 0 Occludin homology domain Med15 PF09606.5 CDJ64695.1 - 0.0011 17.2 26.7 0.0011 17.2 18.5 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ64695.1 - 0.0058 16.3 11.6 0.0058 16.3 8.0 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) SprA-related PF12118.3 CDJ64695.1 - 0.012 15.0 22.5 0.012 14.9 15.6 1.1 1 0 0 1 1 1 0 SprA-related family Spt20 PF12090.3 CDJ64695.1 - 0.016 14.5 6.5 0.017 14.4 4.5 1.3 1 0 0 1 1 1 0 Spt20 family DUF3449 PF11931.3 CDJ64695.1 - 0.028 13.9 5.1 0.032 13.7 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) FimP PF09766.4 CDJ64695.1 - 0.04 12.9 16.3 0.043 12.8 11.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF702 PF05142.7 CDJ64695.1 - 0.045 13.9 7.4 0.059 13.5 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Helicase_RecD PF05127.9 CDJ64695.1 - 0.05 13.2 3.6 0.059 12.9 2.5 1.1 1 0 0 1 1 1 0 Helicase OPT PF03169.10 CDJ64695.1 - 0.055 11.8 0.0 0.06 11.7 0.0 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Tim54 PF11711.3 CDJ64695.1 - 0.056 12.0 3.9 0.053 12.1 2.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 zf-DHHC PF01529.15 CDJ64695.1 - 0.081 12.3 0.6 0.077 12.3 0.4 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CDJ64695.1 - 0.09 13.0 4.5 0.087 13.1 3.1 1.1 1 0 0 1 1 1 0 AAA domain DUF3682 PF12446.3 CDJ64695.1 - 0.095 12.9 23.6 0.14 12.4 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) SAGA-Tad1 PF12767.2 CDJ64695.1 - 0.12 12.0 9.2 0.13 11.9 6.4 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.2 CDJ64695.1 - 0.14 9.7 3.6 0.14 9.8 2.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GBP_C PF02841.9 CDJ64695.1 - 0.16 11.1 14.2 0.19 10.9 9.9 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RR_TM4-6 PF06459.7 CDJ64695.1 - 0.16 11.8 6.2 0.16 11.8 4.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gag_spuma PF03276.9 CDJ64695.1 - 0.17 10.1 16.1 0.17 10.2 11.1 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF3450 PF11932.3 CDJ64695.1 - 0.18 11.0 18.2 0.22 10.7 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cyto_heme_lyase PF01265.12 CDJ64695.1 - 0.19 11.3 7.8 0.18 11.3 5.4 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase FLO_LFY PF01698.11 CDJ64695.1 - 0.24 10.2 4.7 0.26 10.0 3.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AUX_IAA PF02309.11 CDJ64695.1 - 0.25 11.0 3.9 0.26 10.9 2.7 1.1 1 0 0 1 1 1 0 AUX/IAA family AIF_C PF14721.1 CDJ64695.1 - 0.3 11.3 7.0 0.39 10.9 4.9 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDJ64695.1 - 0.33 8.5 24.0 0.38 8.3 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FHIPEP PF00771.15 CDJ64695.1 - 0.34 9.1 5.5 0.4 8.9 3.8 1.0 1 0 0 1 1 1 0 FHIPEP family DUF913 PF06025.7 CDJ64695.1 - 0.35 9.5 3.2 0.34 9.6 2.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SurE PF01975.12 CDJ64695.1 - 0.36 10.1 3.1 0.45 9.7 2.1 1.1 1 0 0 1 1 1 0 Survival protein SurE PAT1 PF09770.4 CDJ64695.1 - 0.43 8.7 26.6 0.4 8.8 18.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDJ64695.1 - 0.5 8.0 5.1 0.52 7.9 3.5 1.0 1 0 0 1 1 1 0 Ycf1 ATAD4 PF15321.1 CDJ64695.1 - 0.57 11.2 4.9 0.72 10.8 3.4 1.4 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Ctr PF04145.10 CDJ64695.1 - 0.62 10.1 3.8 0.74 9.8 2.6 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF1675 PF07897.6 CDJ64695.1 - 0.64 9.8 5.1 0.62 9.8 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDHD PF02862.12 CDJ64695.1 - 0.78 9.5 5.9 0.84 9.3 4.1 1.1 1 0 0 1 1 1 0 DDHD domain FYDLN_acid PF09538.5 CDJ64695.1 - 0.95 10.0 4.5 1.3 9.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2215 PF10225.4 CDJ64695.1 - 1.4 8.3 3.2 1.7 8.0 2.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Serinc PF03348.10 CDJ64695.1 - 1.4 7.5 7.9 1.6 7.3 5.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF912 PF06024.7 CDJ64695.1 - 1.4 8.9 5.1 1.8 8.6 3.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TFIIA PF03153.8 CDJ64695.1 - 1.5 8.6 24.7 1.7 8.4 17.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.5 CDJ64695.1 - 1.5 8.5 3.6 1.6 8.4 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Baculo_PP31 PF05311.6 CDJ64695.1 - 1.5 8.0 8.7 1.7 7.8 6.0 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DOR PF14839.1 CDJ64695.1 - 1.7 8.3 14.7 1.8 8.2 10.2 1.1 1 0 0 1 1 1 0 DOR family CDK2AP PF09806.4 CDJ64695.1 - 1.7 8.8 13.7 1.9 8.6 9.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein R_equi_Vir PF05526.6 CDJ64695.1 - 1.8 8.1 9.0 2.3 7.8 6.2 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Spore_coat_CotO PF14153.1 CDJ64695.1 - 1.8 7.9 14.3 2.2 7.7 9.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO MDFI PF15316.1 CDJ64695.1 - 1.9 8.4 5.0 2.1 8.3 3.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor OATP PF03137.15 CDJ64695.1 - 1.9 6.4 4.5 2.1 6.2 3.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4557 PF15101.1 CDJ64695.1 - 2 8.2 16.7 2.3 8.0 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) UPF0560 PF10577.4 CDJ64695.1 - 2.1 6.5 13.4 2 6.5 9.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pex14_N PF04695.8 CDJ64695.1 - 2.7 8.0 20.5 3.7 7.5 14.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RIC3 PF15361.1 CDJ64695.1 - 3 8.0 10.8 4.2 7.5 7.5 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Peptidase_S49_N PF08496.5 CDJ64695.1 - 4.2 7.1 7.5 5.4 6.8 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3260 PF11658.3 CDJ64695.1 - 4.2 5.3 8.3 4.6 5.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Band_3_cyto PF07565.8 CDJ64695.1 - 4.6 6.6 8.9 5.2 6.4 6.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gastrin PF00918.12 CDJ64695.1 - 5 7.9 13.8 7.4 7.4 9.6 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Spore_YhcN_YlaJ PF09580.5 CDJ64695.1 - 5.5 7.0 11.4 6.7 6.7 7.9 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TCP PF03634.8 CDJ64695.1 - 6 7.2 16.1 8.1 6.8 11.2 1.2 1 0 0 1 1 1 0 TCP family transcription factor Presenilin PF01080.12 CDJ64695.1 - 6.4 5.4 6.2 6.9 5.3 4.3 1.0 1 0 0 1 1 1 0 Presenilin LIM_bind PF01803.11 CDJ64695.1 - 6.7 5.7 14.0 8.2 5.4 9.7 1.1 1 0 0 1 1 1 0 LIM-domain binding protein EPL1 PF10513.4 CDJ64695.1 - 6.8 6.9 12.4 7.7 6.7 8.6 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF3373 PF11853.3 CDJ64695.1 - 6.9 5.0 12.1 8.4 4.7 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) APC_CDC26 PF10471.4 CDJ64695.1 - 7.2 7.4 23.1 15 6.3 16.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF775 PF05603.7 CDJ64695.1 - 7.2 6.0 11.5 8.4 5.8 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF788 PF05620.6 CDJ64695.1 - 9.5 6.0 10.0 13 5.6 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) G0-G1_switch_2 PF15103.1 CDJ64695.1 - 9.9 6.4 9.5 14 5.9 6.6 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 WD40 PF00400.27 CDJ64696.1 - 1.6e-05 24.6 24.0 0.013 15.3 0.0 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF966 PF06136.8 CDJ64696.1 - 0.0051 16.2 5.5 0.0089 15.4 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF966) Hira PF07569.6 CDJ64696.1 - 0.57 9.3 0.0 0.57 9.3 0.0 2.7 3 1 0 3 3 3 0 TUP1-like enhancer of split Peptidase_S49_N PF08496.5 CDJ64696.1 - 4.2 7.1 7.3 1.1 9.0 0.4 2.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal PAT1 PF09770.4 CDJ64696.1 - 6 4.9 37.4 8.8 4.4 26.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_5 PF12695.2 CDJ64698.1 - 0.083 12.6 7.6 2.1 8.0 5.3 2.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ64698.1 - 0.13 12.0 21.7 0.82 9.5 6.1 2.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Herpes_UL87 PF03043.9 CDJ64698.1 - 0.2 9.9 2.7 0.28 9.5 1.9 1.4 1 1 0 1 1 1 0 Herpesvirus UL87 family HlyD_2 PF12700.2 CDJ64698.1 - 0.62 9.1 6.5 0.87 8.6 4.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Suf PF05843.9 CDJ64698.1 - 0.67 9.6 17.1 1.2 8.7 11.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 CDJ64698.1 - 1.2 6.7 7.2 1.5 6.4 5.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_YhcN_YlaJ PF09580.5 CDJ64698.1 - 2.6 8.1 13.8 4.4 7.3 9.6 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Presenilin PF01080.12 CDJ64698.1 - 3.8 6.2 4.8 7.2 5.3 3.3 1.4 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.1 CDJ64698.1 - 5.8 7.1 11.0 8.2 6.6 7.6 1.2 1 0 0 1 1 1 0 AAA domain DUF4175 PF13779.1 CDJ64698.1 - 7.3 4.1 37.1 17 2.9 25.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SAGA-Tad1 PF12767.2 CDJ64698.1 - 8 6.0 18.4 12 5.4 12.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RR_TM4-6 PF06459.7 CDJ64698.1 - 8.2 6.2 10.8 17 5.1 7.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 CDJ64698.1 - 9.3 4.3 41.2 17 3.5 28.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ64699.1 - 0.17 10.0 15.8 0.21 9.7 10.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDJ64699.1 - 1.8 8.3 13.8 3.1 7.5 9.5 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA HAUS6_N PF14661.1 CDJ64699.1 - 3 7.1 7.9 4 6.7 5.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YebO PF13974.1 CDJ64700.1 - 1.7 8.4 9.6 2.7 7.8 6.7 1.2 1 0 0 1 1 1 0 YebO-like protein SR-25 PF10500.4 CDJ64701.1 - 0.00066 19.2 29.9 0.00066 19.2 20.7 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Plasmodium_Vir PF05795.6 CDJ64701.1 - 5.3 6.1 6.1 7 5.7 4.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein KAR9 PF08580.5 CDJ64702.1 - 0.26 9.4 4.9 0.32 9.2 3.4 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF1645 PF07816.6 CDJ64702.1 - 9.3 6.6 19.5 18 5.7 13.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) NifU PF01106.12 CDJ64703.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain TFIIA PF03153.8 CDJ64703.1 - 1.5 8.6 11.0 1.9 8.3 7.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L19e PF01280.15 CDJ64704.1 - 1.2e-16 60.7 4.1 1.2e-16 60.7 2.8 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e Cgr1 PF03879.9 CDJ64704.1 - 0.0023 18.0 9.0 0.0023 18.0 6.2 1.7 2 0 0 2 2 2 1 Cgr1 family YhzD PF14120.1 CDJ64704.1 - 0.99 9.3 4.4 0.97 9.3 2.0 1.7 2 0 0 2 2 2 0 YhzD-like protein BRE1 PF08647.6 CDJ64704.1 - 5.7 6.9 15.4 16 5.5 6.8 2.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase PP2C PF00481.16 CDJ64707.1 - 4.3e-10 39.4 0.1 1e-06 28.3 0.0 2.7 2 1 1 3 3 3 2 Protein phosphatase 2C Med15 PF09606.5 CDJ64707.1 - 0.18 9.9 18.5 0.24 9.5 12.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 CDJ64708.1 - 0.00012 21.6 9.2 0.00012 21.6 6.4 7.5 5 3 1 6 6 6 1 IncA protein DcuC PF03606.10 CDJ64708.1 - 7.4 4.6 15.5 0.38 8.9 5.8 2.5 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Proteasome PF00227.21 CDJ64709.1 - 6.1e-57 191.9 0.0 1.9e-39 134.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 CDJ64709.1 - 1.3e-10 40.3 0.9 2.3e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature LAP1C PF05609.7 CDJ64709.1 - 0.062 11.9 0.2 0.079 11.6 0.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DEAD PF00270.24 CDJ64710.1 - 7.6e-22 77.5 0.0 8.5e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 CDJ64710.1 - 0.00041 19.4 0.0 0.00049 19.2 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF2360 PF10152.4 CDJ64710.1 - 0.019 15.2 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) nsp7 PF08716.5 CDJ64710.1 - 0.11 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 nsp7 replicase Helicase_C PF00271.26 CDJ64711.1 - 6e-26 90.1 0.1 1.8e-25 88.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CDJ64711.1 - 0.016 13.6 0.0 0.022 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) zf-LITAF-like PF10601.4 CDJ64712.1 - 1.7 8.6 6.4 1.8 8.4 4.4 1.0 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain TerD PF02342.13 CDJ64713.1 - 7.6e-12 44.9 0.0 4.5e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 TerD domain DUF2730 PF10805.3 CDJ64713.1 - 0.032 13.9 0.5 0.085 12.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Ribosomal_60s PF00428.14 CDJ64714.1 - 0.0052 17.1 8.8 0.015 15.6 6.1 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein CRAL_TRIO PF00650.15 CDJ64714.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain SNF2_N PF00176.18 CDJ64717.1 - 1.8e-71 240.4 1.8 1.8e-71 240.4 1.3 3.3 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDJ64717.1 - 4e-15 55.4 0.0 1.9e-14 53.2 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IP_trans PF02121.13 CDJ64718.1 - 1.3e-44 152.2 0.0 2e-31 109.1 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol transfer protein Oxysterol_BP PF01237.13 CDJ64718.1 - 4.7e-13 48.3 0.0 8.5e-13 47.5 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 CDJ64718.1 - 6e-10 39.2 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CDJ64718.1 - 2.1e-05 24.7 0.2 0.0031 17.7 0.1 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Kinesin PF00225.18 CDJ64719.1 - 8e-87 291.0 0.0 1.4e-86 290.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Hs1pro-1_C PF07014.7 CDJ64719.1 - 0.024 13.9 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Hs1pro-1 protein C-terminus PK PF00224.16 CDJ64721.1 - 4.3e-79 265.6 0.1 1.1e-37 129.4 0.8 3.1 3 0 0 3 3 3 3 Pyruvate kinase, barrel domain PK_C PF02887.11 CDJ64721.1 - 4.1e-15 55.3 0.0 1.5e-14 53.5 0.0 2.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain adh_short PF00106.20 CDJ64722.1 - 5.8e-42 143.4 0.7 1e-41 142.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CDJ64722.1 - 8.4e-29 101.0 1.2 1.1e-28 100.6 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CDJ64722.1 - 5.6e-22 78.2 0.2 1e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CDJ64722.1 - 0.0062 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 CDJ64722.1 - 0.0073 15.4 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 CDJ64722.1 - 0.0088 15.8 1.8 0.0088 15.8 1.2 2.0 1 1 1 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2205 PF10224.4 CDJ64723.1 - 7e-05 22.3 5.2 7e-05 22.3 3.6 2.8 1 1 1 2 2 1 1 Predicted coiled-coil protein (DUF2205) DUF904 PF06005.7 CDJ64723.1 - 0.004 17.4 4.5 0.004 17.4 3.1 3.3 1 1 1 2 2 1 1 Protein of unknown function (DUF904) FlaC_arch PF05377.6 CDJ64723.1 - 0.0087 15.9 1.6 0.024 14.5 1.1 1.8 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) Myosin_tail_1 PF01576.14 CDJ64723.1 - 0.018 12.7 28.6 0.022 12.5 19.8 1.1 1 0 0 1 1 1 0 Myosin tail FLO_LFY PF01698.11 CDJ64723.1 - 0.21 10.4 15.0 0.26 10.0 10.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Mmp37 PF09139.6 CDJ64723.1 - 0.29 10.1 7.9 0.35 9.8 5.5 1.2 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Med15 PF09606.5 CDJ64723.1 - 0.8 7.8 50.5 0.9 7.6 35.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Atg14 PF10186.4 CDJ64723.1 - 1.7 7.5 24.9 2.3 7.0 17.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CDJ64723.1 - 2 6.7 14.6 2.7 6.3 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CDJ64723.1 - 2.1 7.3 26.7 3.1 6.7 18.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CDJ64723.1 - 2.2 6.0 14.7 3.3 5.4 10.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4175 PF13779.1 CDJ64723.1 - 2.7 5.5 45.4 3.8 5.0 31.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDJ64723.1 - 3 5.9 41.9 3.3 5.8 29.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.1 CDJ64723.1 - 3.6 6.7 20.8 4.4 6.4 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Exonuc_VII_L PF02601.10 CDJ64723.1 - 4.2 6.4 22.4 5.4 6.1 15.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit vMSA PF00695.14 CDJ64723.1 - 4.2 6.4 8.1 4.8 6.2 5.6 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF3584 PF12128.3 CDJ64723.1 - 4.5 4.4 36.8 5.5 4.1 25.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MCPVI PF02993.9 CDJ64723.1 - 5.5 7.0 19.3 7.8 6.5 13.4 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Spc7 PF08317.6 CDJ64723.1 - 7.9 5.0 24.6 11 4.5 17.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Bestrophin PF01062.16 CDJ64723.1 - 8.4 5.2 6.2 10 4.9 4.3 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel AAA_13 PF13166.1 CDJ64723.1 - 8.5 4.6 20.1 13 4.0 13.9 1.2 1 0 0 1 1 1 0 AAA domain RINGv PF12906.2 CDJ64725.1 - 1.8e-13 50.3 4.7 3.5e-13 49.3 3.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CDJ64725.1 - 0.028 14.2 4.5 0.062 13.1 3.1 1.6 1 0 0 1 1 1 0 Ring finger domain RVT_1 PF00078.22 CDJ64726.1 - 1.4e-05 24.5 0.0 2.8e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDJ64728.1 - 1.2e-11 44.0 0.2 1.2e-11 44.0 0.1 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDJ64729.1 - 1.2e-14 54.4 0.0 2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 CDJ64730.1 - 5.2e-16 58.8 0.0 6.7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain GLTSCR1 PF15249.1 CDJ64730.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region gag-asp_proteas PF13975.1 CDJ64731.1 - 7.7e-09 35.2 0.1 7.4e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ64731.1 - 1e-08 35.5 0.0 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDJ64731.1 - 7.1e-05 22.6 0.0 0.00026 20.8 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ64731.1 - 0.0058 16.5 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 CDJ64732.1 - 2.5e-08 33.4 13.1 2.1e-06 27.3 1.8 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ64732.1 - 0.035 13.7 2.5 0.035 13.7 1.7 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ64732.1 - 0.17 11.6 8.6 0.27 10.9 1.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ64732.1 - 0.42 10.3 12.0 0.059 13.1 1.8 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 CDJ64732.1 - 0.88 9.1 7.4 0.28 10.7 1.5 2.2 2 0 0 2 2 2 0 Zinc knuckle Choline_transpo PF04515.7 CDJ64733.1 - 2.2e-12 46.4 1.8 2.2e-12 46.4 1.2 2.7 2 1 1 3 3 3 1 Plasma-membrane choline transporter Phostensin_N PF13916.1 CDJ64734.1 - 0.41 10.6 19.6 0.63 10.0 0.6 3.7 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Pol_alpha_B_N PF08418.5 CDJ64734.1 - 6.3 6.2 27.7 0.15 11.5 3.1 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Arena_nucleocap PF00843.12 CDJ64735.1 - 0.014 13.3 0.6 0.028 12.2 0.4 1.4 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein DUF605 PF04652.11 CDJ64736.1 - 1.4 8.2 41.4 2 7.6 28.7 1.3 1 0 0 1 1 1 0 Vta1 like DUF4526 PF15029.1 CDJ64736.1 - 1.6 8.2 4.5 3.3 7.2 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) V-SNARE_C PF12352.3 CDJ64738.1 - 0.00091 19.2 1.0 0.002 18.1 0.7 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CDJ64738.1 - 0.066 13.3 0.2 0.25 11.5 0.2 2.0 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus HTH_27 PF13463.1 CDJ64738.1 - 0.083 13.2 0.3 0.35 11.2 0.1 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain HYLS1_C PF15311.1 CDJ64738.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus FCD PF07729.7 CDJ64738.1 - 0.7 10.2 6.8 11 6.3 0.1 2.2 2 0 0 2 2 2 0 FCD domain LSM PF01423.17 CDJ64739.1 - 1.1e-14 53.7 0.0 1.3e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain ICE2 PF08426.5 CDJ64740.1 - 0.8 8.2 0.0 2.2 6.8 0.0 1.7 1 0 0 1 1 1 0 ICE2 DEAD PF00270.24 CDJ64741.1 - 4.7e-12 45.7 0.1 2.2e-10 40.2 0.0 3.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ64741.1 - 2.4e-08 33.7 0.1 2.4e-08 33.7 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF342 PF03961.8 CDJ64742.1 - 0.014 13.8 6.4 0.019 13.4 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RMMBL PF07521.7 CDJ64743.1 - 5.1e-08 32.5 0.6 8.7e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Cpn60_TCP1 PF00118.19 CDJ64745.1 - 8.7e-105 351.1 0.3 1.4e-104 350.4 0.2 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GBP PF02263.14 CDJ64747.1 - 5.6e-19 68.2 0.0 5.1e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 CDJ64747.1 - 1.9e-12 47.0 19.0 2.8e-12 46.4 13.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain MFS_1 PF07690.11 CDJ64748.1 - 2.5e-11 42.8 19.6 6.4e-11 41.5 13.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ERGIC_N PF13850.1 CDJ64748.1 - 0.28 11.1 1.2 0.68 9.9 0.2 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TRAPPC-Trs85 PF12739.2 CDJ64749.1 - 2.2e-70 237.4 24.5 1.5e-68 231.4 17.0 3.1 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF4175 PF13779.1 CDJ64749.1 - 5.5 4.5 44.6 0.19 9.3 7.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF1980 PF09323.5 CDJ64749.1 - 6 6.5 6.2 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF842 PF05811.8 CDJ64750.1 - 1.1e-24 86.3 12.8 1.2e-24 86.1 8.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Pex19 PF04614.7 CDJ64750.1 - 0.011 15.4 0.2 0.012 15.2 0.2 1.3 1 1 0 1 1 1 0 Pex19 protein family DUF4618 PF15397.1 CDJ64750.1 - 0.074 12.3 1.7 0.091 12.0 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Vicilin_N PF04702.7 CDJ64750.1 - 5.5 6.5 12.1 3.3 7.2 3.2 2.1 1 1 1 2 2 2 0 Vicilin N terminal region Asp PF00026.18 CDJ64753.1 - 1.9e-65 221.1 0.0 2.4e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDJ64753.1 - 1.3e-05 25.1 0.0 3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Spore_YtfJ PF09579.5 CDJ64753.1 - 0.013 15.3 0.4 0.013 15.3 0.3 2.2 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) ATP-synt_E PF05680.7 CDJ64753.1 - 0.032 14.1 1.0 0.057 13.3 0.7 1.3 1 0 0 1 1 1 0 ATP synthase E chain Med15 PF09606.5 CDJ64754.1 - 1.2 7.2 46.5 2 6.5 32.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ64754.1 - 2.7 7.3 5.9 3.2 7.0 0.1 2.5 3 0 0 3 3 3 0 Spt20 family PRELI PF04707.9 CDJ64755.1 - 1.1e-33 116.0 0.0 1.8e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 PRELI-like family MFS_1 PF07690.11 CDJ64756.1 - 2.5e-08 33.0 34.8 2.5e-08 33.0 24.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 CDJ64757.1 - 2e-10 39.9 12.0 2.5e-10 39.6 8.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF788 PF05620.6 CDJ64757.1 - 0.12 12.2 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Rhomboid PF01694.17 CDJ64757.1 - 0.97 9.4 5.5 1.5 8.8 0.1 2.5 2 1 0 2 2 2 0 Rhomboid family Transgly_assoc PF04226.8 CDJ64757.1 - 1.9 8.6 5.6 2.8 8.1 0.4 2.7 2 0 0 2 2 2 0 Transglycosylase associated protein TFIIA PF03153.8 CDJ64759.1 - 0.085 12.7 26.2 0.12 12.2 18.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1183 PF06682.7 CDJ64759.1 - 0.13 11.8 8.4 0.18 11.3 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) PAT1 PF09770.4 CDJ64759.1 - 0.24 9.6 40.1 0.25 9.5 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLRV_ORF5 PF01690.12 CDJ64759.1 - 0.26 10.3 10.3 0.28 10.3 7.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4366 PF14283.1 CDJ64759.1 - 0.47 9.8 7.6 0.73 9.2 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Neur_chan_memb PF02932.11 CDJ64759.1 - 0.88 9.4 6.8 1 9.1 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exonuc_VII_L PF02601.10 CDJ64759.1 - 2.3 7.3 14.5 2.7 7.0 10.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DHHW PF14286.1 CDJ64759.1 - 2.7 7.2 8.9 3.3 6.9 6.1 1.1 1 0 0 1 1 1 0 DHHW protein Ndc1_Nup PF09531.5 CDJ64759.1 - 6.2 5.1 10.8 6.4 5.0 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FUSC PF04632.7 CDJ64759.1 - 7 4.9 11.2 8.7 4.6 7.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2722 PF10846.3 CDJ64759.1 - 7.1 5.5 23.0 0.28 10.1 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Fes1 PF08609.5 CDJ64759.1 - 7.3 7.1 9.8 9.5 6.7 0.7 2.5 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 PAT1 PF09770.4 CDJ64760.1 - 6.4 4.8 23.9 0.62 8.2 9.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2040 PF09745.4 CDJ64761.1 - 5.4 6.8 18.7 0.59 9.9 8.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Ni_hydr_CYTB PF01292.15 CDJ64762.1 - 0.0097 15.3 0.3 0.0097 15.3 0.2 2.0 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 CDJ64762.1 - 0.04 13.2 1.4 0.19 11.0 1.0 2.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ribosomal_60s PF00428.14 CDJ64763.1 - 0.045 14.1 0.3 0.045 14.1 0.2 11.2 5 3 3 8 8 8 0 60s Acidic ribosomal protein DUF3138 PF11336.3 CDJ64765.1 - 0.13 10.3 3.1 0.18 9.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF668 PF05003.7 CDJ64766.1 - 1.6 9.0 30.0 2.7 8.2 7.3 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF668) MCM PF00493.18 CDJ64767.1 - 2.6e-18 65.9 0.2 4e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family TPR_4 PF07721.9 CDJ64767.1 - 7.2 7.3 9.8 0.86 10.2 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3801 PF12687.2 CDJ64768.1 - 0.005 16.4 12.3 0.0061 16.1 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) Med15 PF09606.5 CDJ64768.1 - 0.2 9.8 45.8 0.23 9.6 31.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Apt1 PF10351.4 CDJ64768.1 - 0.33 9.7 12.8 0.33 9.7 8.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF-3_zeta PF05091.7 CDJ64768.1 - 0.35 9.4 13.3 0.35 9.4 9.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.17 CDJ64768.1 - 0.46 9.4 4.7 0.58 9.1 3.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SOBP PF15279.1 CDJ64768.1 - 1.1 9.5 15.6 1.3 9.3 10.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Pap_E4 PF02711.9 CDJ64768.1 - 1.2 10.0 14.3 4.4 8.1 0.1 2.4 2 0 0 2 2 2 0 E4 protein YfhO PF09586.5 CDJ64768.1 - 6 4.7 9.3 6.9 4.5 6.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DivIC PF04977.10 CDJ64768.1 - 7.8 6.0 19.5 26 4.3 13.5 1.9 1 0 0 1 1 1 0 Septum formation initiator VIT1 PF01988.14 CDJ64768.1 - 7.9 5.8 9.3 0.58 9.6 1.4 2.2 2 0 0 2 2 2 0 VIT family TFIIA PF03153.8 CDJ64768.1 - 8 6.2 34.7 13 5.5 24.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4010 PF13194.1 CDJ64769.1 - 0.0071 15.6 1.1 0.017 14.4 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) LMBR1 PF04791.11 CDJ64769.1 - 0.025 13.1 0.0 0.025 13.1 0.0 3.6 3 2 1 4 4 4 0 LMBR1-like membrane protein Med15 PF09606.5 CDJ64771.1 - 0.019 13.1 12.7 0.02 13.1 8.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BTB PF00651.26 CDJ64772.1 - 3.5e-10 39.8 0.0 3.4e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain rve PF00665.21 CDJ64773.1 - 0.00034 20.6 0.2 0.00081 19.4 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 CDJ64773.1 - 0.0074 15.6 0.3 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve PF00665.21 CDJ64774.1 - 0.0052 16.8 0.0 0.0095 16.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDJ64775.1 - 7.2e-16 58.1 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CDJ64775.1 - 4.1e-09 36.8 0.0 8.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ64775.1 - 2.1e-08 33.8 0.1 6.8e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ64775.1 - 6.2e-06 26.0 0.0 1.9e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ64775.1 - 2.8e-05 24.0 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ64775.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF3552 PF12072.3 CDJ64775.1 - 0.023 13.9 1.7 0.037 13.2 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Retrotrans_gag PF03732.12 CDJ64776.1 - 0.0092 16.0 0.0 0.033 14.2 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein PUF PF00806.14 CDJ64778.1 - 0.0016 17.7 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat DUF4414 PF14377.1 CDJ64778.1 - 0.0051 16.7 0.8 0.01 15.7 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) Ribosomal_60s PF00428.14 CDJ64778.1 - 0.0075 16.6 15.7 0.31 11.4 2.7 2.3 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF3446 PF11928.3 CDJ64778.1 - 0.02 15.1 10.1 0.02 15.1 7.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) ORC6 PF05460.8 CDJ64778.1 - 0.067 12.2 1.2 0.086 11.9 0.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DAG_kinase_N PF14513.1 CDJ64778.1 - 0.39 10.9 3.8 5.8 7.1 0.4 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF1633 PF07794.6 CDJ64778.1 - 3.6 5.4 9.0 4.4 5.1 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Rotamase_2 PF13145.1 CDJ64778.1 - 5.2 7.7 9.6 6.1 7.4 3.0 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain TrbI PF03743.9 CDJ64778.1 - 5.9 6.3 6.3 3.8 6.9 0.5 2.0 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein Ipi1_N PF12333.3 CDJ64778.1 - 6.7 6.7 7.4 1.8 8.6 0.7 2.4 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation DUF2029 PF09594.5 CDJ64780.1 - 0.018 14.5 3.6 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) VIT1 PF01988.14 CDJ64780.1 - 0.2 11.1 7.2 0.36 10.2 5.0 1.5 1 1 0 1 1 1 0 VIT family RskA PF10099.4 CDJ64780.1 - 0.64 9.7 21.3 0.076 12.7 6.1 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3995 PF13160.1 CDJ64780.1 - 0.71 9.9 6.5 1.4 9.0 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Med15 PF09606.5 CDJ64780.1 - 1.5 6.9 18.0 1.8 6.6 12.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HC2 PF07382.6 CDJ64782.1 - 2.2 8.1 6.4 2.9 7.7 4.5 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 ALS2CR8 PF15299.1 CDJ64785.1 - 0.0057 16.2 0.6 0.0057 16.2 0.4 1.6 2 0 0 2 2 2 1 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Atg14 PF10186.4 CDJ64785.1 - 0.58 9.0 20.8 0.0087 15.0 9.2 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3573 PF12097.3 CDJ64785.1 - 3.8 6.0 7.4 5.6 5.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF924 PF06041.6 CDJ64786.1 - 0.09 12.5 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) SR-25 PF10500.4 CDJ64786.1 - 0.15 11.4 1.8 0.19 11.1 1.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.17 CDJ64787.1 - 2.5e-20 71.8 0.2 1.6e-16 59.7 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ64787.1 - 3.1e-17 62.3 0.2 4e-14 52.3 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ64787.1 - 0.00026 20.7 0.1 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 CDJ64788.1 - 3e-16 59.2 0.0 6.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Nbs1_C PF08599.5 CDJ64790.1 - 0.089 12.7 0.9 0.089 12.7 0.6 3.5 2 2 1 3 3 3 0 DNA damage repair protein Nbs1 DEAD_2 PF06733.10 CDJ64791.1 - 5.9e-17 61.6 3.3 4.9e-05 22.7 0.0 3.6 3 0 0 3 3 3 3 DEAD_2 SAGA-Tad1 PF12767.2 CDJ64791.1 - 6.2e-05 22.7 6.1 6.2e-05 22.7 4.3 4.3 3 1 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit SR-25 PF10500.4 CDJ64791.1 - 0.0054 16.2 15.0 0.0054 16.2 10.4 4.0 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein ResIII PF04851.10 CDJ64791.1 - 0.006 16.4 0.3 0.006 16.4 0.2 4.0 3 1 1 4 4 4 2 Type III restriction enzyme, res subunit DUF755 PF05501.6 CDJ64791.1 - 0.014 15.4 19.3 0.014 15.4 13.4 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF755) DUF4349 PF14257.1 CDJ64792.1 - 0.0065 15.7 1.1 0.0065 15.7 0.8 8.7 5 2 2 7 7 7 1 Domain of unknown function (DUF4349) Spt20 PF12090.3 CDJ64792.1 - 0.049 12.9 14.4 0.055 12.8 2.6 2.4 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDJ64792.1 - 2.1 7.3 29.1 1.4 7.8 3.9 2.1 2 0 0 2 2 2 0 Fms-interacting protein Adeno_hexon PF01065.14 CDJ64792.1 - 5.3 5.7 14.8 9.6 4.9 10.3 1.3 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Abhydrolase_1 PF00561.15 CDJ64793.1 - 0.00034 20.2 0.3 0.0015 18.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CDJ64793.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Spt20 PF12090.3 CDJ64793.1 - 7 5.9 34.0 0.2 11.0 1.2 5.0 5 0 0 5 5 5 0 Spt20 family Mito_carr PF00153.22 CDJ64797.1 - 9e-39 131.0 1.0 4.7e-17 61.4 0.2 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein Asp PF00026.18 CDJ64798.1 - 7.5e-18 64.8 0.0 1.4e-16 60.6 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease PUB PF09409.5 CDJ64799.1 - 8e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 PUB domain DUF2360 PF10152.4 CDJ64799.1 - 0.035 14.3 4.6 0.084 13.1 3.2 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) EF-hand_1 PF00036.27 CDJ64800.1 - 2e-27 92.3 4.2 2.4e-07 29.5 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDJ64800.1 - 8.8e-26 89.8 1.5 2.6e-12 46.7 0.4 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CDJ64800.1 - 2.6e-24 83.4 3.5 9.1e-07 27.9 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CDJ64800.1 - 7e-20 69.0 3.3 0.0023 17.6 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CDJ64800.1 - 1.3e-14 53.5 8.2 1.6e-05 24.4 1.3 4.7 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CDJ64800.1 - 3e-09 36.9 0.0 0.00088 19.2 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CDJ64800.1 - 2.3e-05 24.0 2.2 0.13 12.0 0.3 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CDJ64800.1 - 0.00064 19.5 0.0 0.02 14.7 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.8 CDJ64800.1 - 0.053 13.0 0.4 5.1 6.6 0.0 3.1 2 1 2 4 4 4 0 Caleosin related protein DUF2935 PF11155.3 CDJ64800.1 - 0.087 12.9 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) VCBS PF13517.1 CDJ64800.1 - 0.23 11.8 3.2 0.52 10.7 0.3 2.7 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2280 PF10045.4 CDJ64801.1 - 0.014 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Coa1 PF08695.5 CDJ64801.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Glyco_transf_90 PF05686.7 CDJ64802.1 - 1.1e-65 221.9 0.0 1.6e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin PF00085.15 CDJ64802.1 - 2.9e-44 149.0 0.0 3.5e-22 78.0 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.1 CDJ64802.1 - 7.6e-11 42.1 1.0 0.0013 18.8 0.1 3.8 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CDJ64802.1 - 5.4e-09 35.9 0.0 0.003 17.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CDJ64802.1 - 1.4e-05 24.6 0.0 0.016 14.7 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin Glyco_trans_1_2 PF13524.1 CDJ64802.1 - 8.8e-05 22.7 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Thioredoxin_6 PF13848.1 CDJ64802.1 - 0.00017 21.4 0.0 0.1 12.3 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDJ64802.1 - 0.00025 21.0 0.2 2.1 8.5 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like ERp29_N PF07912.8 CDJ64802.1 - 0.0025 17.7 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 1 ERp29, N-terminal domain Glutaredoxin PF00462.19 CDJ64802.1 - 0.0093 15.9 0.1 2.7 8.0 0.0 3.3 3 0 0 3 3 3 1 Glutaredoxin Redoxin PF08534.5 CDJ64802.1 - 0.015 14.8 0.1 4.2 6.8 0.0 3.6 4 0 0 4 4 4 0 Redoxin tRNA-synt_1g PF09334.6 CDJ64803.1 - 5e-43 147.2 0.1 9.2e-43 146.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CDJ64803.1 - 2.1e-10 39.2 0.1 1.2e-09 36.7 0.0 1.8 1 1 1 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CDJ64803.1 - 0.00021 20.4 0.0 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HRDC PF00570.18 CDJ64804.1 - 0.007 16.0 0.5 0.013 15.1 0.4 1.4 1 0 0 1 1 1 1 HRDC domain Med15 PF09606.5 CDJ64805.1 - 0.52 8.4 42.4 0.07 11.3 26.4 1.7 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ64805.1 - 5.4 5.1 44.0 8.9 4.4 30.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4598 PF15370.1 CDJ64805.1 - 9 6.6 8.6 0.37 11.0 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4598) Ribosomal_L18e PF00828.14 CDJ64806.1 - 6.2e-21 75.1 0.0 1e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Fibrillarin PF01269.12 CDJ64807.1 - 2.9e-78 261.9 0.0 3.3e-78 261.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CDJ64807.1 - 0.0001 21.9 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DREV PF05219.7 CDJ64807.1 - 0.019 13.8 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_31 PF13847.1 CDJ64807.1 - 0.07 12.7 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain DUF755 PF05501.6 CDJ64808.1 - 0.0077 16.2 28.7 0.013 15.5 19.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Sporozoite_P67 PF05642.6 CDJ64808.1 - 0.011 13.5 11.1 0.014 13.3 7.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF45 PF01863.12 CDJ64808.1 - 0.018 14.8 2.3 0.024 14.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 FimP PF09766.4 CDJ64808.1 - 0.042 12.9 9.4 0.049 12.6 6.5 1.2 1 0 0 1 1 1 0 Fms-interacting protein FHIPEP PF00771.15 CDJ64808.1 - 0.073 11.3 3.0 0.11 10.8 2.1 1.3 1 0 0 1 1 1 0 FHIPEP family SLD3 PF08639.5 CDJ64808.1 - 0.085 11.4 17.5 0.093 11.3 12.1 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF572 PF04502.8 CDJ64808.1 - 0.14 11.3 12.1 0.18 11.0 8.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2217 PF10265.4 CDJ64808.1 - 0.18 10.5 12.6 0.23 10.1 8.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CDJ64808.1 - 0.23 9.7 17.4 0.3 9.3 12.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 CDJ64808.1 - 0.3 10.7 11.4 0.43 10.2 7.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Draxin PF15550.1 CDJ64808.1 - 0.32 10.5 7.9 0.41 10.2 5.5 1.2 1 0 0 1 1 1 0 Draxin RAP1 PF07218.6 CDJ64808.1 - 0.36 8.8 15.9 0.48 8.4 11.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AUX_IAA PF02309.11 CDJ64808.1 - 0.52 10.0 7.3 0.62 9.7 5.1 1.3 1 0 0 1 1 1 0 AUX/IAA family Fmp27_WPPW PF10359.4 CDJ64808.1 - 0.55 8.5 8.3 0.63 8.3 5.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Plasmodium_Vir PF05795.6 CDJ64808.1 - 0.74 8.9 7.4 0.94 8.6 5.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SRP-alpha_N PF04086.8 CDJ64808.1 - 0.74 9.1 12.3 0.87 8.9 8.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Dicty_REP PF05086.7 CDJ64808.1 - 0.86 7.2 5.3 1.1 6.9 3.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_viral_N PF00242.12 CDJ64808.1 - 2.1 7.2 16.9 2.5 7.0 11.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Neur_chan_memb PF02932.11 CDJ64808.1 - 2.1 8.1 8.7 2.6 7.8 6.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 CDJ64808.1 - 2.4 7.8 10.9 3.3 7.4 7.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CDK5_activator PF03261.10 CDJ64808.1 - 2.5 7.3 10.8 3 7.0 7.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SAPS PF04499.10 CDJ64808.1 - 2.8 6.4 9.3 3.1 6.3 6.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CDJ64808.1 - 3.8 5.0 14.7 4.3 4.8 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM51 PF15345.1 CDJ64808.1 - 4.9 6.7 16.5 7.4 6.1 11.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Pex16 PF08610.5 CDJ64808.1 - 5.5 5.8 8.9 7.1 5.5 6.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Peptidase_S64 PF08192.6 CDJ64808.1 - 8.9 4.5 12.1 10 4.2 8.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.4 CDJ64808.1 - 9.6 4.9 13.9 13 4.5 9.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain V4R PF02830.13 CDJ64809.1 - 0.16 11.8 1.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 V4R domain Med15 PF09606.5 CDJ64810.1 - 0.027 12.6 42.1 0.032 12.4 29.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Lin-8 PF03353.10 CDJ64810.1 - 0.52 9.5 29.4 0.69 9.1 20.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.8 CDJ64810.1 - 7.1 6.4 42.4 9.4 6.0 29.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PEX11 PF05648.9 CDJ64811.1 - 3.8e-35 121.1 7.8 5.6e-35 120.6 5.4 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4386 PF14329.1 CDJ64811.1 - 0.04 13.4 37.8 0.076 12.4 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Sporozoite_P67 PF05642.6 CDJ64812.1 - 1.5 6.6 9.1 1.8 6.3 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_S64 PF08192.6 CDJ64812.1 - 6.1 5.0 8.0 7.2 4.8 5.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.8 CDJ64812.1 - 7.4 6.3 26.9 8.4 6.1 18.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 CDJ64812.1 - 8.6 5.6 9.2 9.8 5.4 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SPX PF03105.14 CDJ64813.1 - 0.0012 18.7 7.1 0.0013 18.5 4.9 1.1 1 0 0 1 1 1 1 SPX domain Macoilin PF09726.4 CDJ64813.1 - 0.021 13.1 17.6 0.026 12.8 12.2 1.0 1 0 0 1 1 1 0 Transmembrane protein EMP24_GP25L PF01105.19 CDJ64813.1 - 0.063 12.9 0.5 0.084 12.5 0.4 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Gly-zipper_OmpA PF13436.1 CDJ64813.1 - 0.1 12.2 16.5 0.22 11.1 11.4 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain CAF-1_p150 PF11600.3 CDJ64813.1 - 0.13 11.6 19.3 0.18 11.1 13.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Trans_reg_C PF00486.23 CDJ64813.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.1 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal IncA PF04156.9 CDJ64813.1 - 0.19 11.2 22.8 0.68 9.5 15.8 1.8 1 1 0 1 1 1 0 IncA protein GAS PF13851.1 CDJ64813.1 - 0.23 10.6 11.1 0.31 10.1 7.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.1 CDJ64813.1 - 0.28 11.1 11.2 0.39 10.6 7.8 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Dehydrin PF00257.14 CDJ64813.1 - 0.35 11.1 4.7 0.79 10.0 3.3 1.8 1 1 0 1 1 1 0 Dehydrin DUF972 PF06156.8 CDJ64813.1 - 2.1 8.7 7.0 4.5 7.6 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Atg14 PF10186.4 CDJ64813.1 - 3.6 6.4 13.5 2.4 7.0 8.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S64 PF08192.6 CDJ64813.1 - 3.8 5.7 10.0 4.5 5.4 7.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 TFIIA PF03153.8 CDJ64813.1 - 6.4 6.5 17.9 8.7 6.1 12.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pneumo_att_G PF05539.6 CDJ64813.1 - 6.5 6.0 14.8 7.2 5.8 10.2 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CDC27 PF09507.5 CDJ64813.1 - 8.4 5.4 20.9 12 5.0 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2217 PF10265.4 CDJ64817.1 - 0.041 12.6 0.2 0.041 12.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Ycf1 PF05758.7 CDJ64817.1 - 0.06 11.0 8.2 0.076 10.7 5.7 1.1 1 0 0 1 1 1 0 Ycf1 Rtf2 PF04641.7 CDJ64817.1 - 0.19 10.8 17.1 0.017 14.3 0.7 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger Suf PF05843.9 CDJ64817.1 - 1.3 8.6 14.0 0.18 11.5 4.7 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2360 PF10152.4 CDJ64817.1 - 1.9 8.7 14.1 1.3 9.3 2.9 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Strabismus PF06638.6 CDJ64817.1 - 2.4 6.3 6.2 0.11 10.7 0.2 1.7 2 0 0 2 2 2 0 Strabismus protein ETRAMP PF09716.5 CDJ64817.1 - 3.1 7.8 6.7 0.15 12.0 0.6 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pex14_N PF04695.8 CDJ64817.1 - 4 7.4 16.2 1.3 9.0 8.9 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Radial_spoke_3 PF06098.6 CDJ64817.1 - 5.5 5.9 25.2 1.6 7.6 9.1 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 GAS PF13851.1 CDJ64818.1 - 0.031 13.4 14.6 0.051 12.7 10.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1759 PF03564.10 CDJ64818.1 - 0.3 10.9 0.9 0.56 10.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) LXG PF04740.7 CDJ64818.1 - 0.41 10.4 3.4 0.74 9.5 2.4 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily FCP1_C PF09309.5 CDJ64819.1 - 0.00051 19.4 2.2 0.00051 19.4 1.5 4.5 2 1 2 4 4 4 1 FCP1, C-terminal CorA PF01544.13 CDJ64820.1 - 1.7 7.5 4.0 2.8 6.9 2.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1253 PF06862.7 CDJ64821.1 - 1.7e-76 257.4 14.7 1.9e-44 151.7 0.0 5.4 6 0 0 6 6 6 4 Protein of unknown function (DUF1253) CAF-1_p150 PF11600.3 CDJ64821.1 - 0.00047 19.6 23.8 0.00047 19.6 16.5 6.3 6 0 0 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Abhydrolase_6 PF12697.2 CDJ64823.1 - 7.8e-05 22.6 10.6 0.0032 17.3 7.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDJ64823.1 - 0.0086 15.8 1.5 0.016 14.9 0.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ64823.1 - 0.097 12.2 1.4 0.17 11.4 0.9 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF3299 PF11736.3 CDJ64823.1 - 0.14 12.1 8.2 0.041 13.7 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) SDA1 PF05285.7 CDJ64823.1 - 1.9 7.7 13.1 0.068 12.4 0.4 2.2 2 0 0 2 2 2 0 SDA1 PAT1 PF09770.4 CDJ64823.1 - 3.7 5.6 22.9 0.4 8.8 11.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDJ64823.1 - 4.6 6.8 9.5 2 8.0 4.6 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ64823.1 - 4.8 5.2 30.7 0.52 8.4 16.9 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3513 PF12026.3 CDJ64823.1 - 7.1 6.1 14.9 0.15 11.6 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) Aldo_ket_red PF00248.16 CDJ64825.1 - 3.7e-32 111.2 0.0 2.4e-22 79.0 0.0 2.4 1 1 1 2 2 2 2 Aldo/keto reductase family ABC_tran PF00005.22 CDJ64826.1 - 3.3e-14 53.3 0.0 3.3e-13 50.0 0.0 2.5 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CDJ64826.1 - 0.00084 18.8 0.0 0.00084 18.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CDJ64826.1 - 0.0054 17.0 0.7 0.19 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CDJ64826.1 - 0.032 14.7 0.1 0.071 13.6 0.1 1.5 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 CDJ64826.1 - 0.06 12.5 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CDJ64826.1 - 0.11 12.2 2.3 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 CDJ64827.1 - 4.5e-25 88.5 0.0 1.4e-23 83.6 0.0 2.4 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDJ64827.1 - 0.00029 20.9 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain Dicer_dimer PF03368.9 CDJ64827.1 - 0.0012 18.5 0.0 0.28 10.9 0.0 2.7 1 1 1 2 2 2 1 Dicer dimerisation domain SMC_N PF02463.14 CDJ64827.1 - 0.0025 17.0 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CDJ64827.1 - 0.0029 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CDJ64827.1 - 0.004 16.5 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDJ64827.1 - 0.0067 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.18 CDJ64827.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CDJ64827.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDJ64827.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CDJ64827.1 - 0.2 11.9 0.0 0.33 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Tweety PF04906.8 CDJ64828.1 - 0.021 13.2 16.2 0.037 12.4 5.6 3.3 3 0 0 3 3 3 0 Tweety Prominin PF05478.6 CDJ64828.1 - 0.042 11.3 3.2 0.22 8.9 0.5 2.5 2 0 0 2 2 2 0 Prominin SoxE PF06525.6 CDJ64828.1 - 0.12 11.6 0.6 0.28 10.4 0.4 1.6 1 0 0 1 1 1 0 Sulfocyanin (SoxE) TPM PF04536.9 CDJ64830.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase MMR_HSR1 PF01926.18 CDJ64831.1 - 2.4e-18 66.1 0.0 4.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDJ64831.1 - 6.7e-08 31.9 0.0 2.9e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CDJ64831.1 - 1.3e-06 28.2 0.4 5.9e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 CDJ64831.1 - 2.5e-05 23.5 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 CDJ64831.1 - 0.00027 20.4 0.0 0.06 12.7 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CDJ64831.1 - 0.0041 17.6 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 CDJ64831.1 - 0.0077 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CDJ64831.1 - 0.015 14.8 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CDJ64831.1 - 0.026 14.8 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.12 CDJ64831.1 - 0.027 13.0 0.0 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_21 PF13304.1 CDJ64831.1 - 0.053 13.4 0.1 0.08 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain PTH2 PF01981.11 CDJ64832.1 - 2.4e-06 27.2 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3223 PF11523.3 CDJ64833.1 - 4.3e-09 36.5 0.7 0.00019 21.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3223) DUF3357 PF11837.3 CDJ64833.1 - 0.054 13.3 1.5 0.11 12.3 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF913 PF06025.7 CDJ64833.1 - 1.4 7.5 5.2 1.9 7.1 3.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AUX_IAA PF02309.11 CDJ64833.1 - 3.9 7.1 8.7 5.6 6.6 6.1 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF966 PF06136.8 CDJ64833.1 - 6.6 6.0 16.4 8.8 5.6 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Suf PF05843.9 CDJ64833.1 - 8.3 6.0 13.3 12 5.5 9.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RNase_H2-Ydr279 PF09468.5 CDJ64833.1 - 9.8 5.2 7.4 16 4.5 5.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SR-25 PF10500.4 CDJ64834.1 - 8.8e-06 25.3 22.7 1e-05 25.1 15.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDJ64834.1 - 0.26 10.5 40.3 0.33 10.2 28.0 1.1 1 0 0 1 1 1 0 SprA-related family DUF4207 PF13904.1 CDJ64834.1 - 0.38 10.0 38.5 0.44 9.8 26.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF3984 PF13136.1 CDJ64834.1 - 0.46 9.6 19.9 0.5 9.5 13.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) RR_TM4-6 PF06459.7 CDJ64834.1 - 0.84 9.4 18.3 1 9.1 12.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAF-1_p150 PF11600.3 CDJ64834.1 - 0.94 8.8 28.3 1.2 8.4 19.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Suf PF05843.9 CDJ64834.1 - 1.6 8.3 24.8 2.1 8.0 17.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDJ64834.1 - 1.6 8.0 25.9 1.9 7.7 18.0 1.0 1 0 0 1 1 1 0 Vta1 like Corona_nucleoca PF00937.13 CDJ64834.1 - 2.5 6.9 27.9 2.9 6.7 19.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein NPR3 PF03666.8 CDJ64834.1 - 2.7 6.4 18.2 3.1 6.2 12.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BNIP3 PF06553.7 CDJ64834.1 - 2.9 7.2 18.6 3.8 6.8 12.9 1.3 1 0 0 1 1 1 0 BNIP3 G-7-MTase PF12803.2 CDJ64834.1 - 4 6.4 10.8 4.3 6.3 7.5 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DDHD PF02862.12 CDJ64834.1 - 5.8 6.6 22.8 7.2 6.3 15.8 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.1 CDJ64834.1 - 6.9 6.8 15.3 10 6.2 10.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FMN_dh PF01070.13 CDJ64834.1 - 7.4 5.3 8.3 7.3 5.3 5.8 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase CDK5_activator PF03261.10 CDJ64834.1 - 9.2 5.4 19.7 10 5.3 13.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Serinc PF03348.10 CDJ64834.1 - 9.5 4.8 14.3 12 4.5 9.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Bul1_N PF04425.7 CDJ64834.1 - 9.9 4.5 15.4 10 4.5 10.7 1.1 1 0 0 1 1 1 0 Bul1 N terminus Inositol_P PF00459.20 CDJ64836.1 - 1.3e-34 119.7 0.0 7.2e-32 110.7 0.0 3.2 1 1 0 1 1 1 1 Inositol monophosphatase family DUF4131 PF13567.1 CDJ64837.1 - 0.067 12.5 5.0 1.6 8.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4186 PF13811.1 CDJ64837.1 - 0.16 11.6 9.8 1.8 8.3 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4186) Dehydrin PF00257.14 CDJ64837.1 - 0.21 11.9 22.6 5.3 7.3 3.2 3.3 2 2 1 3 3 3 0 Dehydrin MR_MLE_C PF13378.1 CDJ64837.1 - 0.28 11.1 10.7 4.3 7.3 0.3 3.2 3 0 0 3 3 3 0 Enolase C-terminal domain-like K_channel_TID PF07941.6 CDJ64837.1 - 0.29 11.3 38.9 0.92 9.7 3.7 3.4 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain BAF1_ABF1 PF04684.8 CDJ64837.1 - 0.41 9.4 48.7 0.047 12.5 12.3 3.1 1 1 2 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor GHMP_kinases_N PF00288.21 CDJ64837.1 - 0.71 9.9 15.2 8.4 6.5 0.1 3.6 3 0 0 3 3 3 0 GHMP kinases N terminal domain RskA PF10099.4 CDJ64837.1 - 0.98 9.1 30.5 0.41 10.3 2.7 3.2 1 1 2 3 3 3 0 Anti-sigma-K factor rskA WBP-1 PF11669.3 CDJ64837.1 - 2.1 8.4 15.2 0.67 10.0 1.7 2.9 3 0 0 3 3 3 0 WW domain-binding protein 1 Ada_Zn_binding PF02805.11 CDJ64837.1 - 2.2 7.9 12.8 3.9 7.1 0.8 3.9 3 1 0 3 3 3 0 Metal binding domain of Ada PepSY_2 PF13670.1 CDJ64837.1 - 2.4 8.1 33.6 4.1 7.3 4.1 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Macoilin PF09726.4 CDJ64837.1 - 4.6 5.4 33.3 6 5.0 23.1 1.1 1 0 0 1 1 1 0 Transmembrane protein CytochromB561_N PF09786.4 CDJ64837.1 - 5.5 5.3 20.2 7.2 4.9 14.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal PGAP1 PF07819.8 CDJ64838.1 - 7.8e-14 51.7 0.0 7.8e-14 51.7 0.0 2.9 3 1 0 3 3 3 1 PGAP1-like protein IncA PF04156.9 CDJ64838.1 - 0.00012 21.7 7.5 0.00012 21.7 5.2 19.1 18 4 0 19 19 19 2 IncA protein TMEM51 PF15345.1 CDJ64838.1 - 0.0043 16.7 0.5 0.0043 16.7 0.4 13.3 12 2 2 14 14 14 1 Transmembrane protein 51 Ctr PF04145.10 CDJ64838.1 - 0.015 15.3 0.3 0.015 15.3 0.2 14.0 11 3 2 13 13 13 0 Ctr copper transporter family DUF676 PF05057.9 CDJ64838.1 - 0.034 13.4 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF912 PF06024.7 CDJ64838.1 - 2.7 8.1 0.0 2.7 8.1 0.0 10.4 12 1 0 12 12 12 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NIF PF03031.13 CDJ64840.1 - 1.7e-05 24.5 0.0 0.00011 21.9 0.0 1.9 1 1 1 2 2 2 1 NLI interacting factor-like phosphatase RNase_H2-Ydr279 PF09468.5 CDJ64841.1 - 2.9e-15 56.2 0.0 7.3e-15 54.9 0.0 1.6 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Nrap PF03813.9 CDJ64842.1 - 5.6e-91 305.5 0.0 8.1e-43 146.1 0.0 4.2 4 0 0 4 4 4 4 Nrap protein Ank_2 PF12796.2 CDJ64844.1 - 1.4e-26 92.6 0.3 1.6e-15 57.1 0.0 4.4 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ64844.1 - 2.1e-25 87.2 3.3 1.2e-06 28.0 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 CDJ64844.1 - 1.5e-22 77.3 0.3 4.4e-05 23.3 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CDJ64844.1 - 6.3e-21 74.3 0.1 1.5e-12 47.6 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDJ64844.1 - 3.2e-15 55.7 0.0 1.3e-08 34.8 0.0 4.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) CLAG PF03805.8 CDJ64844.1 - 0.33 8.2 0.0 0.46 7.7 0.0 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein DUF342 PF03961.8 CDJ64846.1 - 8.3 4.7 13.9 12 4.1 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Trichoplein PF13868.1 CDJ64847.1 - 4.3e-44 150.3 142.8 4.3e-44 150.3 99.0 2.3 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin RPAP2_Rtr1 PF04181.8 CDJ64848.1 - 4.7e-08 33.0 2.4 5.6e-08 32.7 0.5 2.2 2 0 0 2 2 2 1 Rtr1/RPAP2 family Cpn10 PF00166.16 CDJ64849.1 - 9.8e-17 60.6 0.0 1.2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Herpes_gE PF02480.11 CDJ64849.1 - 0.12 10.6 0.0 0.14 10.4 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ThiF PF00899.16 CDJ64850.1 - 2.8e-37 127.5 0.0 6e-37 126.4 0.0 1.5 1 1 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 CDJ64850.1 - 0.0011 18.0 0.1 0.31 9.9 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 CDJ64850.1 - 0.007 16.5 0.0 0.026 14.7 0.0 1.9 1 1 0 1 1 1 1 Putative NAD(P)-binding MoeZ_MoeB PF05237.8 CDJ64850.1 - 0.031 13.8 0.8 0.069 12.7 0.1 2.0 2 0 0 2 2 2 0 MoeZ/MoeB domain Shikimate_DH PF01488.15 CDJ64850.1 - 0.046 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Arm PF00514.18 CDJ64851.1 - 0.00033 20.3 14.5 0.28 11.0 0.0 8.9 10 0 0 10 10 10 2 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 CDJ64851.1 - 0.034 13.7 0.2 3.9 7.0 0.0 3.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) AAA PF00004.24 CDJ64853.1 - 5.7e-43 146.2 0.0 8.2e-37 126.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CDJ64853.1 - 7.6e-07 28.7 0.1 1.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CDJ64853.1 - 1.9e-06 28.6 0.0 0.0026 18.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CDJ64853.1 - 9.5e-06 25.7 3.1 0.12 12.3 0.3 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CDJ64853.1 - 0.00017 21.7 0.1 0.37 10.9 0.1 3.4 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CDJ64853.1 - 0.00017 21.7 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 CDJ64853.1 - 0.00033 20.5 0.0 0.0045 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDJ64853.1 - 0.00099 18.8 2.0 0.0043 16.7 0.2 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 CDJ64853.1 - 0.0014 18.5 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDJ64853.1 - 0.0023 17.0 0.0 0.0051 15.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 CDJ64853.1 - 0.0049 16.2 0.8 0.093 12.1 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 CDJ64853.1 - 0.0076 15.9 0.4 0.18 11.5 0.1 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CDJ64853.1 - 0.0078 16.5 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 1 ABC transporter PhoH PF02562.11 CDJ64853.1 - 0.01 15.0 0.1 0.13 11.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.7 CDJ64853.1 - 0.018 14.0 0.0 0.14 11.1 0.1 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 CDJ64853.1 - 0.018 14.7 0.0 21 4.6 0.0 3.1 2 1 1 3 3 3 0 Archaeal ATPase NACHT PF05729.7 CDJ64853.1 - 0.028 14.0 0.1 1.8 8.1 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 CDJ64853.1 - 0.029 14.3 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CDJ64853.1 - 0.067 12.3 0.5 0.18 10.9 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CDJ64853.1 - 0.19 12.0 0.2 0.87 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain PEX-1N PF09262.6 CDJ64854.1 - 2.2e-12 46.8 0.0 4.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal ACBP PF00887.14 CDJ64855.1 - 1.2e-23 82.5 1.0 3.2e-23 81.1 0.7 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein CbiC PF02570.10 CDJ64855.1 - 1.1 8.5 6.5 0.63 9.4 0.1 2.9 3 0 0 3 3 3 0 Precorrin-8X methylmutase TFIIA PF03153.8 CDJ64855.1 - 4.6 7.0 42.8 0.58 10.0 5.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Mmp37 PF09139.6 CDJ64856.1 - 1.3e-47 162.4 0.0 2.8e-47 161.3 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 SSF PF00474.12 CDJ64857.1 - 9.6e-15 54.1 19.3 3e-14 52.4 13.4 1.9 1 1 0 1 1 1 1 Sodium:solute symporter family DUF2561 PF10812.3 CDJ64857.1 - 0.0013 18.3 0.3 0.0013 18.3 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2561) GNAT_acetyltr_2 PF13718.1 CDJ64858.1 - 5.6e-68 228.1 0.0 1.8e-67 226.4 0.0 1.9 1 1 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CDJ64858.1 - 5.4e-57 192.2 0.0 1.6e-56 190.7 0.0 1.9 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 CDJ64858.1 - 1.2e-24 85.7 0.0 2.6e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CDJ64858.1 - 5.6e-21 74.5 0.2 2e-20 72.7 0.1 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 CDJ64858.1 - 0.00014 21.7 0.0 0.0005 20.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDJ64858.1 - 0.0011 19.0 0.0 0.0058 16.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Nop14 PF04147.7 CDJ64858.1 - 0.72 7.7 12.4 1.1 7.1 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family PCMT PF01135.14 CDJ64859.1 - 9.6e-40 136.3 0.0 9.6e-40 136.3 0.0 2.0 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 CDJ64859.1 - 6.6e-07 29.0 0.2 1.5e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ64859.1 - 3.3e-06 27.6 0.0 8.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CDJ64859.1 - 0.008 15.8 0.0 0.008 15.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ64859.1 - 0.019 15.0 1.5 0.074 13.0 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain ASFV_J13L PF05568.6 CDJ64859.1 - 0.032 13.7 2.1 0.067 12.7 1.4 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Baculo_PP31 PF05311.6 CDJ64859.1 - 4.7 6.3 14.2 6.1 6.0 9.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) OATP PF03137.15 CDJ64859.1 - 8.1 4.3 6.2 13 3.7 4.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family eIF-3_zeta PF05091.7 CDJ64859.1 - 8.6 4.8 19.8 11 4.5 13.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Chorein_N PF12624.2 CDJ64862.1 - 1.1e-19 70.1 0.0 5.4e-19 67.8 0.0 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CDJ64862.1 - 1.3e-09 37.6 0.0 3.4e-08 33.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) LMBR1 PF04791.11 CDJ64862.1 - 4 5.9 0.0 11 4.4 0.0 1.7 1 0 0 1 1 1 0 LMBR1-like membrane protein tRNA-synt_1e PF01406.14 CDJ64862.1 - 7.4 5.5 0.0 16 4.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Lge1 PF11488.3 CDJ64863.1 - 0.12 12.6 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Kinesin PF00225.18 CDJ64864.1 - 9.8e-42 142.8 0.3 9.8e-42 142.8 0.2 4.6 3 1 1 4 4 4 1 Kinesin motor domain EFP_N PF08207.7 CDJ64865.1 - 6e-05 22.8 0.0 9.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Shadoo PF14999.1 CDJ64865.1 - 0.019 14.8 4.0 0.025 14.4 2.8 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF2993 PF11209.3 CDJ64865.1 - 0.037 13.9 0.0 0.056 13.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2993) Ribosomal_60s PF00428.14 CDJ64865.1 - 0.61 10.5 10.9 1.2 9.5 7.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3355 PF11835.3 CDJ64865.1 - 1.4 8.7 3.3 2.2 8.0 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) ATP_bind_3 PF01171.15 CDJ64866.1 - 5.6e-17 61.8 0.3 9.8e-08 31.7 0.9 3.8 3 1 1 4 4 4 2 PP-loop family Sporozoite_P67 PF05642.6 CDJ64866.1 - 0.0003 18.8 0.0 0.0003 18.8 0.0 4.8 3 2 1 4 4 4 1 Sporozoite P67 surface antigen AAA_23 PF13476.1 CDJ64866.1 - 0.0066 16.7 8.3 1.7 8.9 4.1 2.3 2 0 0 2 2 2 2 AAA domain EIIBC-GUT_N PF03612.9 CDJ64866.1 - 0.029 14.0 0.4 0.029 14.0 0.3 2.0 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2392 PF10288.4 CDJ64866.1 - 0.033 14.5 0.5 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) PAPS_reduct PF01507.14 CDJ64866.1 - 0.078 12.7 0.1 0.23 11.2 0.1 1.9 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family zf-C2H2_jaz PF12171.3 CDJ64868.1 - 0.002 18.2 0.4 0.002 18.2 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding S1 PF00575.18 CDJ64869.1 - 9.8e-15 54.4 0.0 3.4e-05 23.8 0.0 4.0 3 1 0 3 3 3 3 S1 RNA binding domain S1_2 PF13509.1 CDJ64869.1 - 0.0079 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 S1 domain PRP21_like_P PF12230.3 CDJ64870.1 - 0.081 12.4 3.9 0.13 11.7 2.7 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein SNF2_N PF00176.18 CDJ64870.1 - 0.091 11.5 0.1 0.29 9.9 0.0 1.7 2 0 0 2 2 2 0 SNF2 family N-terminal domain Spt20 PF12090.3 CDJ64872.1 - 0.14 11.4 4.5 0.13 11.6 3.1 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.3 CDJ64872.1 - 0.17 11.0 10.6 0.15 11.2 7.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RAB3GAP2_N PF14655.1 CDJ64872.1 - 0.21 10.5 3.9 0.18 10.7 2.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF788 PF05620.6 CDJ64872.1 - 9.8 5.9 7.2 13 5.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DDRGK PF09756.4 CDJ64873.1 - 0.3 10.4 19.7 0.068 12.5 7.5 2.1 2 0 0 2 2 2 0 DDRGK domain zf-ZPR1 PF03367.8 CDJ64873.1 - 2.5 7.2 11.4 0.38 9.8 2.5 2.5 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Hepcidin PF06446.7 CDJ64873.1 - 2.5 8.5 6.4 0.44 10.9 0.3 2.2 2 0 0 2 2 2 0 Hepcidin LNS2 PF08235.8 CDJ64874.1 - 2.7e-53 179.7 0.0 4e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) FlgD PF03963.9 CDJ64875.1 - 0.088 12.8 2.1 0.2 11.7 1.5 1.5 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region Hamartin PF04388.7 CDJ64875.1 - 4.4 5.8 7.3 4.7 5.7 5.0 1.0 1 0 0 1 1 1 0 Hamartin protein BAF1_ABF1 PF04684.8 CDJ64877.1 - 0.00034 19.6 19.2 0.00034 19.6 13.3 8.1 2 2 3 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.14 CDJ64877.1 - 0.0045 17.3 7.6 0.0045 17.3 5.3 5.6 4 1 1 5 5 5 1 60s Acidic ribosomal protein PAS PF00989.19 CDJ64878.1 - 0.0054 16.4 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold BLVR PF06375.6 CDJ64878.1 - 0.012 15.4 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) FimP PF09766.4 CDJ64878.1 - 0.021 13.9 1.9 0.025 13.6 1.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Draxin PF15550.1 CDJ64878.1 - 0.1 12.2 3.5 0.12 12.0 2.4 1.2 1 0 0 1 1 1 0 Draxin DUF966 PF06136.8 CDJ64878.1 - 0.13 11.6 2.4 0.13 11.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) UPF0560 PF10577.4 CDJ64878.1 - 0.21 9.8 5.0 0.24 9.6 3.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2453 PF10507.4 CDJ64878.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF2453) DUF2217 PF10265.4 CDJ64878.1 - 0.49 9.0 2.9 0.57 8.8 2.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) BORG_CEP PF14957.1 CDJ64878.1 - 0.78 10.6 3.4 1 10.2 2.3 1.2 1 0 0 1 1 1 0 Cdc42 effector Caps_assemb_Wzi PF14052.1 CDJ64878.1 - 1.4 7.7 4.8 1.6 7.5 3.4 1.0 1 0 0 1 1 1 0 Capsule assembly protein Wzi PAT1 PF09770.4 CDJ64878.1 - 3.3 5.8 15.9 3.7 5.6 11.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.7 CDJ64878.1 - 5 5.6 6.3 6.1 5.3 4.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LRR_6 PF13516.1 CDJ64879.1 - 2.8e-05 23.7 0.4 1.3 9.3 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich repeat MMR_HSR1_C PF08438.5 CDJ64882.1 - 1.1e-22 80.3 0.0 2.5e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CDJ64882.1 - 1.3e-16 60.5 0.0 2.8e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDJ64882.1 - 3.8e-06 26.2 0.1 8.5e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.16 CDJ64882.1 - 0.00091 19.0 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain ATP_bind_1 PF03029.12 CDJ64882.1 - 0.031 13.8 1.2 0.72 9.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Apc4_WD40 PF12894.2 CDJ64883.1 - 0.019 14.4 0.1 0.051 13.0 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.17 CDJ64884.1 - 1.6e-39 133.4 0.0 8.9e-21 73.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ64884.1 - 3.1e-28 97.5 0.0 1.8e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ64884.1 - 4.9e-19 67.9 0.0 1.6e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CDJ64884.1 - 0.012 15.1 0.1 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 CDJ64884.1 - 0.035 13.8 0.0 0.23 11.2 0.0 1.9 1 1 1 2 2 2 0 Limkain b1 Amino_oxidase PF01593.19 CDJ64885.1 - 7e-16 58.3 17.1 2.1e-06 27.1 2.9 3.4 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDJ64885.1 - 2.5e-09 37.0 1.1 1.4e-08 34.6 0.8 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CDJ64885.1 - 6.3e-05 23.2 2.4 0.00016 21.9 1.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDJ64885.1 - 0.0001 22.4 0.9 0.00022 21.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDJ64885.1 - 0.0001 22.2 0.6 0.0001 22.2 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDJ64885.1 - 0.00033 19.2 1.7 0.00055 18.5 1.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CDJ64885.1 - 0.028 13.5 2.2 0.053 12.5 1.5 1.3 1 0 0 1 1 1 0 Thi4 family Abhydrolase_5 PF12695.2 CDJ64886.1 - 4.2e-09 36.3 0.0 1.9e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ64886.1 - 1.2e-07 31.8 8.6 1.4e-07 31.6 1.4 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDJ64886.1 - 1.6e-06 27.9 0.1 0.0079 16.0 0.0 2.5 2 0 0 2 2 2 2 Putative lysophospholipase COPI_assoc PF08507.5 CDJ64887.1 - 3.4e-12 46.2 5.0 4.6e-12 45.7 3.5 1.1 1 0 0 1 1 1 1 COPI associated protein DUF3096 PF11295.3 CDJ64887.1 - 0.13 11.7 0.3 0.13 11.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) MxiH PF09392.5 CDJ64889.1 - 1.7 9.2 5.6 19 5.8 0.0 2.2 2 0 0 2 2 2 0 Type III secretion needle MxiH like Ribosomal_60s PF00428.14 CDJ64889.1 - 3.4 8.1 35.8 0.65 10.4 2.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Prominin PF05478.6 CDJ64889.1 - 6.8 4.0 12.3 6.5 4.1 8.5 1.1 1 0 0 1 1 1 0 Prominin GTP_EFTU PF00009.22 CDJ64890.1 - 3.7e-17 62.3 0.0 1.1e-08 34.7 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 CDJ64890.1 - 0.031 13.9 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Myc_N PF01056.13 CDJ64891.1 - 0.096 11.8 12.6 0.027 13.6 6.7 1.5 1 1 1 2 2 2 0 Myc amino-terminal region DUF1183 PF06682.7 CDJ64891.1 - 2.2 7.7 7.2 3.1 7.3 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) UbiA PF01040.13 CDJ64892.1 - 8.2e-18 64.5 30.9 1.1e-16 60.8 11.2 3.2 3 0 0 3 3 3 2 UbiA prenyltransferase family SR-25 PF10500.4 CDJ64892.1 - 1.5 8.2 5.9 2.2 7.6 4.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CDJ64893.1 - 3.4e-05 22.3 6.2 4.3e-05 22.0 4.3 1.1 1 0 0 1 1 1 1 Transmembrane protein TFIIA PF03153.8 CDJ64893.1 - 0.015 15.2 12.4 0.023 14.6 8.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDJ64893.1 - 0.054 13.3 3.7 0.092 12.6 2.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 CDJ64893.1 - 0.087 11.1 0.8 0.13 10.4 0.6 1.3 1 0 0 1 1 1 0 Membrane transport protein PAT1 PF09770.4 CDJ64893.1 - 0.25 9.5 18.3 0.42 8.8 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 CDJ64893.1 - 0.29 9.9 14.6 0.4 9.4 10.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.10 CDJ64893.1 - 1.2 7.7 9.0 1.6 7.2 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0560 PF10577.4 CDJ64893.1 - 2.6 6.1 17.7 4.3 5.4 12.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SpoIIIAH PF12685.2 CDJ64893.1 - 4 6.8 17.7 7.2 6.0 12.3 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Cyto_heme_lyase PF01265.12 CDJ64893.1 - 4 6.9 15.2 6.7 6.2 10.5 1.3 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Spc7_N PF15402.1 CDJ64893.1 - 4.6 5.1 28.1 6.8 4.5 19.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF966 PF06136.8 CDJ64893.1 - 5.3 6.3 27.1 8.1 5.7 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CytochromB561_N PF09786.4 CDJ64893.1 - 5.5 5.3 22.8 8.4 4.7 15.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Lin-8 PF03353.10 CDJ64893.1 - 5.6 6.1 15.8 9.3 5.4 10.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4647 PF15504.1 CDJ64893.1 - 6 5.6 18.9 8.2 5.1 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF4407 PF14362.1 CDJ64893.1 - 6.2 5.6 5.8 9.9 5.0 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FHIPEP PF00771.15 CDJ64893.1 - 6.6 4.9 6.0 9 4.4 4.2 1.0 1 0 0 1 1 1 0 FHIPEP family HemX PF04375.9 CDJ64894.1 - 0.00046 18.8 6.1 0.00082 18.0 4.2 1.3 1 0 0 1 1 1 1 HemX DUF605 PF04652.11 CDJ64894.1 - 0.28 10.5 13.8 0.33 10.2 9.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF3457 PF11939.3 CDJ64894.1 - 3.1 7.2 10.3 0.081 12.4 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3457) Pex14_N PF04695.8 CDJ64894.1 - 3.8 7.5 14.9 0.58 10.2 1.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.14 CDJ64895.1 - 0.44 10.9 0.1 0.44 10.9 0.1 4.9 4 1 0 4 4 4 0 60s Acidic ribosomal protein RNase_E_G PF10150.4 CDJ64895.1 - 9.3 5.3 21.3 0.061 12.5 6.3 2.2 1 1 0 2 2 2 0 Ribonuclease E/G family Med15 PF09606.5 CDJ64896.1 - 6.4 4.8 22.2 7.1 4.7 15.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAS PF13851.1 CDJ64897.1 - 0.0012 18.0 8.2 0.0015 17.7 5.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding COG5 PF10392.4 CDJ64897.1 - 0.0024 17.8 1.2 0.0034 17.3 0.8 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF812 PF05667.6 CDJ64897.1 - 0.0053 15.3 4.7 0.0055 15.2 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF972 PF06156.8 CDJ64897.1 - 0.014 15.6 1.6 0.014 15.6 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) WXG100 PF06013.7 CDJ64897.1 - 0.027 14.4 0.6 0.027 14.4 0.4 4.0 2 1 2 4 4 4 0 Proteins of 100 residues with WXG RNase_E_G PF10150.4 CDJ64897.1 - 0.045 12.9 3.8 0.061 12.5 2.7 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family DUF4446 PF14584.1 CDJ64897.1 - 0.095 12.5 2.4 0.13 12.0 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) APG6 PF04111.7 CDJ64897.1 - 0.15 11.0 8.9 0.19 10.7 6.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_M56 PF05569.6 CDJ64897.1 - 0.17 10.8 1.9 0.24 10.3 1.3 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 CENP-F_leu_zip PF10473.4 CDJ64897.1 - 0.24 11.2 9.2 0.34 10.7 6.4 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 CDJ64897.1 - 0.62 9.8 5.5 0.3 10.8 0.5 2.6 2 2 1 3 3 3 0 Homeobox associated leucine zipper Prominin PF05478.6 CDJ64897.1 - 0.79 7.1 3.3 0.91 6.9 2.3 1.1 1 0 0 1 1 1 0 Prominin DUF898 PF05987.8 CDJ64897.1 - 1.2 7.9 10.8 1.5 7.5 7.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) HAUS6_N PF14661.1 CDJ64897.1 - 1.2 8.4 11.1 1.7 7.9 7.6 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3450 PF11932.3 CDJ64897.1 - 2 7.5 27.9 28 3.8 19.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3373 PF11853.3 CDJ64897.1 - 3.7 5.9 6.9 6.7 5.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) DivIC PF04977.10 CDJ64897.1 - 6.5 6.3 7.5 0.62 9.5 1.0 2.3 1 1 2 3 3 3 0 Septum formation initiator Abhydrolase_4 PF08386.5 CDJ64898.1 - 0.011 15.6 0.8 0.011 15.6 0.6 2.1 2 1 0 2 2 2 0 TAP-like protein BrkDBD PF09607.5 CDJ64898.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.3 2 0 0 2 2 2 0 Brinker DNA-binding domain APC_CDC26 PF10471.4 CDJ64898.1 - 0.16 12.6 9.1 2 9.2 2.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 YjeF_N PF03853.10 CDJ64898.1 - 1 8.9 9.0 12 5.4 3.8 2.3 1 1 1 2 2 2 0 YjeF-related protein N-terminus P12 PF12669.2 CDJ64898.1 - 6.2 7.1 9.4 12 6.1 4.9 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family ATP11 PF06644.6 CDJ64899.1 - 5e-12 45.8 0.6 5.6e-05 22.7 0.0 2.5 1 1 2 3 3 3 2 ATP11 protein Sec1 PF00995.18 CDJ64900.1 - 6e-34 117.6 0.0 6.3e-29 101.0 0.0 3.1 2 1 0 2 2 2 2 Sec1 family Spt20 PF12090.3 CDJ64900.1 - 0.019 14.3 0.2 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 Spt20 family 60KD_IMP PF02096.15 CDJ64900.1 - 0.021 14.4 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Suf PF05843.9 CDJ64900.1 - 0.089 12.5 1.3 0.12 12.0 0.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.4 CDJ64900.1 - 0.1 10.8 5.7 0.14 10.4 4.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.1 CDJ64900.1 - 0.39 8.3 10.9 0.54 7.9 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDJ64900.1 - 2.1 6.5 12.9 2.9 6.0 9.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tubulin PF00091.20 CDJ64901.1 - 1.8e-13 50.8 0.0 1.2e-05 25.2 0.0 3.1 2 1 1 3 3 3 3 Tubulin/FtsZ family, GTPase domain ELH PF02323.10 CDJ64903.1 - 0.061 12.4 2.9 0.065 12.3 2.0 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor Phage_lysis PF03245.8 CDJ64903.1 - 0.13 12.2 1.5 0.13 12.2 1.1 1.1 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Cap_synth_GfcB PF11102.3 CDJ64903.1 - 0.19 11.2 0.7 0.22 11.0 0.5 1.0 1 0 0 1 1 1 0 Group 4 capsule polysaccharide formation lipoprotein gfcB SR-25 PF10500.4 CDJ64903.1 - 1.7 8.0 6.9 2.2 7.6 4.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.17 CDJ64904.1 - 1.5e-48 162.2 0.1 1.5e-16 59.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ64904.1 - 1.6e-39 133.6 0.0 7.5e-13 48.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ64904.1 - 4.5e-25 87.2 0.1 4.8e-08 32.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 CDJ64904.1 - 0.00027 20.7 0.8 0.00049 19.9 0.5 1.4 1 0 0 1 1 1 1 WW domain DUF4651 PF15513.1 CDJ64904.1 - 0.038 13.4 0.0 2.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) Ctr PF04145.10 CDJ64905.1 - 0.16 11.9 0.6 1.7 8.7 0.0 2.0 2 0 0 2 2 2 0 Ctr copper transporter family Cytidylate_kin PF02224.13 CDJ64906.1 - 0.3 10.5 1.4 7.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase Phostensin_N PF13916.1 CDJ64906.1 - 2.5 8.1 7.7 5.6 7.0 2.0 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal YgbB PF02542.11 CDJ64908.1 - 1.8e-47 161.0 0.5 5.1e-42 143.3 0.3 2.5 3 0 0 3 3 3 2 YgbB family RNA_pol PF00940.14 CDJ64909.1 - 2.1e-130 434.8 0.0 3.5e-130 434.1 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CDJ64909.1 - 1.1e-21 77.3 1.9 7.8e-14 51.6 0.4 5.7 4 2 1 5 5 5 3 DNA-directed RNA polymerase N-terminal Peptidase_C15 PF01470.12 CDJ64912.1 - 5.2e-18 65.6 0.0 1.7e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase Cluap1 PF10234.4 CDJ64913.1 - 5.7e-08 32.2 12.2 6.3e-08 32.1 0.6 2.4 2 0 0 2 2 2 2 Clusterin-associated protein-1 FlaC_arch PF05377.6 CDJ64913.1 - 0.19 11.6 1.1 0.73 9.7 0.7 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Helicase_C PF00271.26 CDJ64914.1 - 3.1e-24 84.6 0.1 7e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDJ64914.1 - 2.3e-13 49.9 0.0 9.3e-13 48.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SR-25 PF10500.4 CDJ64916.1 - 0.0015 18.0 5.5 0.0015 18.0 3.8 4.7 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Guanylate_cyc_2 PF09778.4 CDJ64918.1 - 1.2e-26 93.2 0.0 8.2e-19 67.6 0.0 3.3 3 1 0 3 3 3 3 Guanylylate cyclase Peptidase_C39 PF03412.10 CDJ64918.1 - 0.016 15.0 0.2 0.016 15.0 0.1 1.9 2 0 0 2 2 2 0 Peptidase C39 family DUF3335 PF11814.3 CDJ64918.1 - 0.054 12.6 4.0 2.8 7.0 0.0 2.9 3 0 0 3 3 3 0 Peptidase_C39 like family Phytochelatin PF05023.9 CDJ64918.1 - 1 8.2 4.4 0.16 10.8 0.1 1.8 2 0 0 2 2 2 0 Phytochelatin synthase RRM_5 PF13893.1 CDJ64919.1 - 3.1e-14 52.5 0.0 4.5e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ64919.1 - 1.8e-09 37.0 0.0 3.4e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ64919.1 - 9e-07 28.7 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3446 PF11928.3 CDJ64919.1 - 0.6 10.3 12.2 0.9 9.7 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Cnd1 PF12717.2 CDJ64920.1 - 0.0035 17.2 0.1 0.0094 15.8 0.0 1.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CDJ64920.1 - 0.0086 16.0 2.1 47 4.4 0.0 4.5 5 0 0 5 5 5 2 HEAT repeat RAB3GAP2_N PF14655.1 CDJ64922.1 - 0.021 13.8 1.5 0.021 13.8 1.0 3.1 3 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Coatamer_beta_C PF07718.7 CDJ64922.1 - 0.3 10.7 0.0 0.3 10.7 0.0 2.4 3 0 0 3 3 3 0 Coatomer beta C-terminal region Cnd2 PF05786.9 CDJ64923.1 - 4e-31 108.2 10.1 9.3e-24 83.9 5.0 4.0 3 1 0 4 4 4 2 Condensin complex subunit 2 Med15 PF09606.5 CDJ64923.1 - 0.001 17.4 67.3 0.008 14.4 7.4 3.3 3 0 0 3 3 3 3 ARC105 or Med15 subunit of Mediator complex non-fungal PepSY_2 PF13670.1 CDJ64925.1 - 2.6 8.0 18.2 2 8.3 0.8 2.3 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 CDJ64926.1 - 0.52 10.7 68.2 0.2 12.0 2.9 4.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein WD40 PF00400.27 CDJ64931.1 - 5e-42 140.3 29.3 4.9e-05 23.0 1.0 11.3 12 0 0 12 12 12 9 WD domain, G-beta repeat PQQ_3 PF13570.1 CDJ64931.1 - 3.3e-05 23.9 1.6 24 5.3 0.0 7.2 8 0 0 8 8 8 0 PQQ-like domain eIF2A PF08662.6 CDJ64931.1 - 0.00013 21.7 0.0 0.028 14.1 0.0 3.9 4 3 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CDJ64931.1 - 0.0003 20.3 0.0 0.028 13.9 0.0 3.1 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 CDJ64931.1 - 0.00075 18.3 2.4 0.24 10.0 1.7 3.0 1 1 2 3 3 3 2 Nup133 N terminal like Reg_prop PF07494.6 CDJ64931.1 - 0.011 15.6 0.1 51 4.3 0.0 4.9 4 0 0 4 4 4 0 Two component regulator propeller PD40 PF07676.7 CDJ64931.1 - 0.054 13.1 0.0 40 4.0 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TMF_DNA_bd PF12329.3 CDJ64932.1 - 0.00024 20.8 7.6 0.00065 19.4 3.7 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 CDJ64932.1 - 0.0033 17.2 8.5 0.0074 16.1 4.4 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CDJ64932.1 - 0.0043 16.2 0.8 0.0055 15.9 0.5 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF1664 PF07889.7 CDJ64932.1 - 0.0045 16.7 3.7 0.11 12.2 2.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) ADIP PF11559.3 CDJ64932.1 - 0.0054 16.6 4.8 0.033 14.1 2.3 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Spectrin PF00435.16 CDJ64932.1 - 0.0056 16.9 5.6 0.057 13.7 3.9 2.0 1 1 0 1 1 1 1 Spectrin repeat APG6 PF04111.7 CDJ64932.1 - 0.012 14.7 3.7 0.014 14.5 2.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CCDC155 PF14662.1 CDJ64932.1 - 0.013 15.1 5.4 0.016 14.8 3.7 1.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Spc7 PF08317.6 CDJ64932.1 - 0.013 14.1 3.9 0.018 13.6 2.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 CDJ64932.1 - 0.013 13.2 3.1 0.016 12.9 2.2 1.0 1 0 0 1 1 1 0 Myosin tail MAP65_ASE1 PF03999.7 CDJ64932.1 - 0.015 13.9 3.3 0.018 13.6 2.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Prefoldin_2 PF01920.15 CDJ64932.1 - 0.016 14.9 2.7 2.5 7.8 2.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit LXG PF04740.7 CDJ64932.1 - 0.018 14.8 4.5 0.022 14.5 3.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Syntaxin-6_N PF09177.6 CDJ64932.1 - 0.019 15.3 3.3 0.033 14.5 2.3 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Cast PF10174.4 CDJ64932.1 - 0.032 12.2 6.0 0.041 11.9 4.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF2951 PF11166.3 CDJ64932.1 - 0.039 13.7 2.5 0.068 13.0 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) Scaffolding_pro PF11418.3 CDJ64932.1 - 0.043 14.1 0.7 0.082 13.2 0.3 1.6 1 1 0 1 1 1 0 Phi29 scaffolding protein DUF1690 PF07956.6 CDJ64932.1 - 0.043 13.7 5.0 0.064 13.2 3.4 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) IFT57 PF10498.4 CDJ64932.1 - 0.044 12.5 5.0 0.019 13.7 0.9 1.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Fmp27_WPPW PF10359.4 CDJ64932.1 - 0.045 12.1 3.2 0.059 11.7 2.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Med9 PF07544.8 CDJ64932.1 - 0.048 13.3 0.8 0.048 13.3 0.5 2.5 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF724 PF05266.9 CDJ64932.1 - 0.057 13.0 1.6 0.07 12.7 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.4 CDJ64932.1 - 0.058 12.3 5.2 0.073 11.9 3.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMCO5 PF14992.1 CDJ64932.1 - 0.059 12.4 2.9 0.069 12.2 2.0 1.1 1 0 0 1 1 1 0 TMCO5 family FliD_N PF02465.13 CDJ64932.1 - 0.06 13.7 2.6 1 9.7 1.8 2.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Baculo_PEP_C PF04513.7 CDJ64932.1 - 0.067 13.0 3.9 0.24 11.2 2.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mating_N PF12731.2 CDJ64932.1 - 0.069 13.0 3.0 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Mating-type protein beta 1 HrpB7 PF09486.5 CDJ64932.1 - 0.075 12.9 2.2 0.38 10.6 0.6 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Phenol_Hydrox PF02332.13 CDJ64932.1 - 0.076 12.3 0.1 0.092 12.0 0.1 1.1 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase Ead_Ea22 PF13935.1 CDJ64932.1 - 0.077 13.3 0.6 0.09 13.1 0.4 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein C9orf72-like PF15019.1 CDJ64932.1 - 0.078 12.2 0.2 0.099 11.8 0.2 1.1 1 0 0 1 1 1 0 C9orf72-like protein family MutS_III PF05192.13 CDJ64932.1 - 0.12 12.0 1.9 0.16 11.7 1.3 1.1 1 0 0 1 1 1 0 MutS domain III IncA PF04156.9 CDJ64932.1 - 0.14 11.7 13.4 0.76 9.3 9.3 1.8 1 1 0 1 1 1 0 IncA protein THDPS_N_2 PF14805.1 CDJ64932.1 - 0.14 12.0 0.5 0.52 10.2 0.1 2.1 1 1 1 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal FliJ PF02050.11 CDJ64932.1 - 0.14 12.2 8.6 0.04 13.9 1.2 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein SlyX PF04102.7 CDJ64932.1 - 0.15 12.4 8.1 0.32 11.4 0.5 3.0 2 1 1 3 3 3 0 SlyX DivIVA PF05103.8 CDJ64932.1 - 0.16 12.0 3.4 2.4 8.2 1.2 2.6 1 1 2 3 3 3 0 DivIVA protein FUSC PF04632.7 CDJ64932.1 - 0.17 10.2 0.7 0.18 10.2 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBCA PF02970.11 CDJ64932.1 - 0.17 11.9 2.2 0.92 9.6 1.7 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A Ran-binding PF05508.6 CDJ64932.1 - 0.18 10.6 2.0 0.23 10.3 1.4 1.2 1 0 0 1 1 1 0 RanGTP-binding protein TMF_TATA_bd PF12325.3 CDJ64932.1 - 0.19 11.4 6.4 0.41 10.3 4.4 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Rsd_AlgQ PF04353.8 CDJ64932.1 - 0.21 11.2 2.7 0.44 10.2 0.5 1.9 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF3618 PF12277.3 CDJ64932.1 - 0.24 11.4 1.5 0.4 10.7 0.2 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3618) Snapin_Pallidin PF14712.1 CDJ64932.1 - 0.24 11.7 7.8 1.8 8.9 3.7 2.4 1 1 1 2 2 2 0 Snapin/Pallidin HalX PF08663.5 CDJ64932.1 - 0.36 10.8 6.1 11 6.1 0.2 3.1 2 1 1 3 3 3 0 HalX domain DUF4200 PF13863.1 CDJ64932.1 - 0.37 10.7 5.5 2.4 8.0 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Bacillus_HBL PF05791.6 CDJ64932.1 - 0.4 10.0 4.0 0.59 9.4 2.8 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.8 CDJ64932.1 - 0.63 9.5 4.8 2 7.9 3.3 1.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 CDJ64932.1 - 0.72 10.1 4.9 20 5.5 1.3 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein K1377 PF15352.1 CDJ64932.1 - 0.81 7.5 4.3 0.85 7.4 3.0 1.0 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Nup54 PF13874.1 CDJ64932.1 - 0.93 9.1 4.9 1.3 8.6 2.4 1.8 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin PF02996.12 CDJ64932.1 - 1.3 8.6 5.0 5.3 6.7 0.2 2.6 1 1 1 3 3 3 0 Prefoldin subunit Cortex-I_coil PF09304.5 CDJ64932.1 - 1.7 8.7 7.1 2.4 8.2 4.6 1.5 1 1 0 1 1 1 0 Cortexillin I, coiled coil FlxA PF14282.1 CDJ64932.1 - 1.7 8.6 11.5 0.23 11.4 4.2 2.0 1 1 1 2 2 2 0 FlxA-like protein Bap31 PF05529.7 CDJ64932.1 - 1.9 7.9 4.8 3.3 7.1 3.4 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like OmpH PF03938.9 CDJ64932.1 - 4.6 7.1 6.7 11 5.9 4.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 CDJ64932.1 - 7.8 6.0 10.7 5.1 6.6 0.8 2.9 1 1 2 3 3 3 0 Septum formation initiator DivIC PF04977.10 CDJ64933.1 - 0.65 9.5 3.4 2.4 7.6 0.7 2.5 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 CDJ64933.1 - 1.1 8.7 10.1 0.37 10.3 1.9 2.5 1 1 1 2 2 2 0 IncA protein Laps PF10169.4 CDJ64933.1 - 6.5 7.0 7.9 1.3 9.2 2.2 2.2 1 1 1 2 2 2 0 Learning-associated protein Glyco_hydro_77 PF02446.12 CDJ64934.1 - 6.1e-45 153.7 0.4 1e-27 96.9 0.0 2.1 2 0 0 2 2 2 2 4-alpha-glucanotransferase Ribosomal_60s PF00428.14 CDJ64936.1 - 2.8e-22 78.9 13.0 3.7e-22 78.5 9.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DEC-1_N PF04625.8 CDJ64936.1 - 0.52 8.9 3.9 0.56 8.8 2.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TraT PF05818.7 CDJ64938.1 - 0.0053 16.1 2.4 0.0053 16.1 1.6 6.1 6 2 0 6 6 6 1 Enterobacterial TraT complement resistance protein Ribosomal_60s PF00428.14 CDJ64938.1 - 0.011 16.1 6.1 0.011 16.1 4.2 6.5 6 1 0 6 6 6 0 60s Acidic ribosomal protein zinc_ribbon_2 PF13240.1 CDJ64938.1 - 0.2 11.2 2.5 0.42 10.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain BMF PF15185.1 CDJ64939.1 - 8.3 5.6 11.0 0.34 10.1 3.1 1.9 1 1 2 3 3 3 0 Bcl-2-modifying factor, apoptosis zf-CCCH PF00642.19 CDJ64941.1 - 1.6e-16 59.5 23.0 6.5e-06 25.6 0.2 4.6 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDJ64941.1 - 3.1e-12 45.9 24.6 1.1e-05 25.1 1.2 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 CDJ64942.1 - 8.6e-17 61.1 0.0 8.6e-17 61.1 0.0 3.2 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64942.1 - 5e-07 29.0 0.0 5e-07 29.0 0.0 2.9 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2341 PF10102.4 CDJ64943.1 - 2.7 8.2 10.8 31 4.8 0.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2341) AMH_N PF04709.7 CDJ64943.1 - 3.5 6.4 9.7 4.3 6.1 6.7 1.3 1 1 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Retrotrans_gag PF03732.12 CDJ64944.1 - 0.056 13.5 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.22 CDJ64945.1 - 3.2e-17 62.6 0.0 5.7e-17 61.7 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDJ64946.1 - 4.5e-16 59.0 0.0 1.7e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 CDJ64946.1 - 0.0032 16.8 0.5 0.0071 15.7 0.3 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger ACDC PF14733.1 CDJ64948.1 - 2.3e-09 37.2 0.0 5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CDJ64948.1 - 3e-07 30.4 0.3 3e-07 30.4 0.2 3.3 3 0 0 3 3 3 1 AP2 domain Activator_LAG-3 PF11498.3 CDJ64948.1 - 1.2 7.8 25.7 0.067 11.9 12.4 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 IFP_35_N PF07334.8 CDJ64950.1 - 0.078 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Myco_arth_vir_N PF09610.5 CDJ64953.1 - 1.9 8.4 4.0 1.6 8.7 1.4 1.9 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Hydrolase_3 PF08282.7 CDJ64954.1 - 1.8e-35 122.7 0.0 9e-20 71.3 0.0 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CDJ64954.1 - 4.1e-10 39.3 0.0 0.0002 20.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CDJ64954.1 - 3.1e-07 31.0 0.0 1.4e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ64954.1 - 0.00032 20.9 0.1 0.086 12.9 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CDJ64954.1 - 0.00033 20.4 0.0 0.00071 19.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 CDJ64954.1 - 0.0079 15.5 0.0 0.078 12.3 0.0 2.0 1 1 1 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) D-aminoacyl_C PF07908.7 CDJ64954.1 - 0.28 10.5 2.8 0.76 9.1 0.2 2.4 2 0 0 2 2 2 0 D-aminoacylase, C-terminal region zf-B_box PF00643.19 CDJ64955.1 - 6.5e-09 35.5 19.0 6.1e-05 22.8 3.8 3.0 3 0 0 3 3 3 2 B-box zinc finger PARP PF00644.15 CDJ64955.1 - 0.0013 18.2 0.4 0.048 13.0 0.1 2.5 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Cript PF10235.4 CDJ64955.1 - 0.0048 17.2 5.5 0.012 15.9 2.3 2.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF3135 PF11333.3 CDJ64955.1 - 0.098 12.8 1.8 0.15 12.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) DUF45 PF01863.12 CDJ64959.1 - 2.9 7.6 11.0 0.5 10.1 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 RNB PF00773.14 CDJ64960.1 - 2e-15 56.8 3.6 2.9e-13 49.8 0.0 2.9 3 0 0 3 3 3 2 RNB domain DivIC PF04977.10 CDJ64960.1 - 0.75 9.3 7.2 1.4 8.4 5.0 1.4 1 0 0 1 1 1 0 Septum formation initiator SR-25 PF10500.4 CDJ64961.1 - 0.0046 16.4 15.7 0.0054 16.2 10.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4482 PF14818.1 CDJ64961.1 - 0.1 13.2 1.0 0.11 13.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) THRAP3_BCLAF1 PF15440.1 CDJ64961.1 - 0.53 8.8 10.8 0.59 8.7 7.5 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family ICAP-1_inte_bdg PF10480.4 CDJ64961.1 - 0.57 9.9 4.7 0.66 9.7 3.2 1.1 1 0 0 1 1 1 0 Beta-1 integrin binding protein DUF566 PF04484.7 CDJ64961.1 - 0.88 9.0 9.1 0.97 8.8 6.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) CT47 PF15623.1 CDJ64961.1 - 1.4 8.6 9.2 1.8 8.2 6.4 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Period_C PF12114.3 CDJ64961.1 - 1.7 8.2 9.5 1.8 8.1 6.6 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF2217 PF10265.4 CDJ64961.1 - 1.8 7.2 4.8 1.8 7.2 3.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DNA_pol_viral_N PF00242.12 CDJ64961.1 - 2.3 7.1 5.6 2.4 7.0 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF755 PF05501.6 CDJ64961.1 - 3.7 7.6 23.3 5.3 7.1 16.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RAP1 PF07218.6 CDJ64961.1 - 3.8 5.4 12.9 4.1 5.3 9.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDK2AP PF09806.4 CDJ64961.1 - 4 7.6 9.5 6.1 7.0 6.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Macoilin PF09726.4 CDJ64961.1 - 5 5.2 8.7 5.3 5.2 6.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 CDJ64961.1 - 7.3 4.9 9.2 8.5 4.7 6.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Apt1 PF10351.4 CDJ64961.1 - 8 5.1 6.1 8.2 5.1 4.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain 14-3-3 PF00244.15 CDJ64962.1 - 2.6e-07 29.9 3.9 2.6e-07 29.9 2.7 2.3 3 1 0 3 3 3 1 14-3-3 protein Chorion_2 PF03964.10 CDJ64962.1 - 0.012 16.1 2.0 0.012 16.1 1.4 2.5 2 0 0 2 2 2 0 Chorion family 2 DSHCT PF08148.7 CDJ64962.1 - 0.014 14.6 2.9 1.5 8.0 0.1 2.6 2 0 0 2 2 2 0 DSHCT (NUC185) domain DXP_synthase_N PF13292.1 CDJ64962.1 - 0.031 13.2 1.1 0.063 12.1 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DUF3371 PF11851.3 CDJ64962.1 - 0.8 10.4 25.6 0.59 10.8 2.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) Med15 PF09606.5 CDJ64963.1 - 0.38 8.8 33.2 0.29 9.2 16.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Corona_nucleoca PF00937.13 CDJ64963.1 - 0.63 8.9 28.9 0.025 13.5 13.8 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Suf PF05843.9 CDJ64963.1 - 1.6 8.3 17.4 0.2 11.3 7.5 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ64963.1 - 5.6 6.7 40.1 4.4 7.0 4.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 CDJ64964.1 - 5.1e-21 74.9 0.0 3.9e-17 62.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 CDJ64964.1 - 2.3e-17 62.8 0.0 1.6e-16 60.1 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDJ64964.1 - 9.4e-06 24.8 0.0 5e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1292 PF06949.6 CDJ64964.1 - 0.093 13.0 2.7 1.5 9.2 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) ACBP PF00887.14 CDJ64965.1 - 4.9e-24 83.8 0.0 8.4e-24 83.0 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.25 CDJ64965.1 - 4.9e-18 63.9 0.4 7.4e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CDJ64965.1 - 1.8e-15 57.0 0.1 2.8e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDJ64965.1 - 3e-15 55.9 0.1 6.3e-09 35.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ64965.1 - 8.3e-11 41.0 0.1 5.5e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CDJ64965.1 - 2.3e-10 40.7 0.0 0.00012 22.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Peptidase_A24 PF01478.13 CDJ64967.1 - 4.2 7.5 12.2 5.5 7.2 6.6 2.3 2 1 0 2 2 2 0 Type IV leader peptidase family PseudoU_synth_2 PF00849.17 CDJ64969.1 - 4.4e-25 88.4 0.0 7.1e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase rve PF00665.21 CDJ64970.1 - 2.2e-17 63.2 0.0 5e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CDJ64970.1 - 0.0002 21.1 1.9 0.00046 19.9 1.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Ribosomal_L33 PF00471.15 CDJ64971.1 - 2.8e-10 40.2 0.0 5.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L33 Fes1 PF08609.5 CDJ64974.1 - 0.02 15.3 0.1 0.45 11.0 0.0 2.9 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 ATP_bind_4 PF01902.12 CDJ64975.1 - 3.8e-21 75.4 0.0 8e-21 74.4 0.0 1.5 1 1 0 1 1 1 1 ATP-binding region AAA PF00004.24 CDJ64976.1 - 7.4e-29 100.6 0.1 1.7e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CDJ64976.1 - 3.7e-06 26.7 1.1 8.7e-05 22.3 0.4 2.7 1 1 1 2 2 2 1 Vps4 C terminal oligomerisation domain DnaJ PF00226.26 CDJ64977.1 - 3.2e-22 78.0 0.3 3.2e-22 78.0 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain MscS_porin PF12795.2 CDJ64977.1 - 0.58 9.4 6.8 0.22 10.8 1.8 2.4 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain GYF PF02213.11 CDJ64978.1 - 1.5e-07 30.9 0.0 3.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 GYF domain Pkinase PF00069.20 CDJ64979.1 - 2.4e-20 72.8 0.0 5e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ64979.1 - 1.1e-10 41.1 0.0 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ64979.1 - 1e-07 31.2 0.2 2.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like DUF4259 PF14078.1 CDJ64979.1 - 0.71 10.3 4.5 2.5 8.6 3.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) MOZ_SAS PF01853.13 CDJ64980.1 - 9.8e-52 174.9 0.2 2.7e-37 127.8 0.3 2.2 1 1 1 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.3 CDJ64980.1 - 1.7e-09 37.2 0.0 4.1e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain DUF4590 PF15257.1 CDJ64980.1 - 0.092 12.5 1.7 0.29 10.9 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4590) LEA_3 PF03242.8 CDJ64980.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein Ribosomal_S16 PF00886.14 CDJ64981.1 - 2.7e-15 55.7 0.0 5.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S16 Pkinase PF00069.20 CDJ64983.1 - 2.1e-19 69.7 0.0 5.7e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 CDJ64983.1 - 3.1e-12 46.0 0.0 3.2e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_Tyr PF07714.12 CDJ64983.1 - 2.5e-07 30.0 0.0 5.7e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase MCM PF00493.18 CDJ64984.1 - 8.3e-108 360.0 3.9 3.8e-55 187.0 0.0 3.7 3 1 0 3 3 3 2 MCM2/3/5 family MCM_N PF14551.1 CDJ64984.1 - 9e-06 26.1 0.0 6e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CDJ64984.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Clathrin_lg_ch PF01086.12 CDJ64985.1 - 4.2e-08 33.4 10.8 4.2e-08 33.4 7.5 2.2 2 0 0 2 2 2 1 Clathrin light chain IncA PF04156.9 CDJ64985.1 - 0.0021 17.6 4.3 0.0021 17.6 3.0 2.2 2 0 0 2 2 2 2 IncA protein DUF755 PF05501.6 CDJ64985.1 - 0.015 15.3 13.6 0.015 15.3 9.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Esterase PF00756.15 CDJ64985.1 - 0.018 14.4 2.6 0.22 10.9 0.6 2.1 2 0 0 2 2 2 0 Putative esterase GEMIN8 PF15348.1 CDJ64985.1 - 1.6 8.7 20.9 0.7 9.9 6.6 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 PAT1 PF09770.4 CDJ64985.1 - 8.3 4.5 33.9 12 4.0 23.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA-synt_2 PF00152.15 CDJ64986.1 - 7.1e-47 159.8 3.6 2.7e-45 154.6 0.0 4.1 3 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CDJ64986.1 - 0.00067 18.9 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CDJ64986.1 - 0.006 16.4 0.0 0.051 13.4 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain HATPase_c_5 PF14501.1 CDJ64986.1 - 0.17 11.6 0.0 0.48 10.1 0.0 1.7 1 0 0 1 1 1 0 GHKL domain DUF3446 PF11928.3 CDJ64987.1 - 0.028 14.5 25.0 0.4 10.9 3.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Pheromone PF08015.6 CDJ64987.1 - 0.58 11.0 12.4 6.7 7.6 0.5 3.8 3 0 0 3 3 3 0 Fungal mating-type pheromone ERCC4 PF02732.10 CDJ64988.1 - 2.5e-15 56.5 0.2 9.1e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain Spt20 PF12090.3 CDJ64988.1 - 0.13 11.5 10.5 0.41 9.9 0.3 3.3 3 0 0 3 3 3 0 Spt20 family Activator_LAG-3 PF11498.3 CDJ64988.1 - 0.14 10.8 38.1 0.33 9.6 0.3 3.9 3 0 0 3 3 3 0 Transcriptional activator LAG-3 RAB3GAP2_N PF14655.1 CDJ64988.1 - 0.66 8.9 20.4 0.32 9.9 1.6 3.3 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDJ64988.1 - 2.7 7.6 23.5 2.3 7.8 1.6 4.4 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) GCFC PF07842.7 CDJ64989.1 - 6.7e-33 114.2 11.0 6.7e-33 114.2 7.6 2.2 2 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 CDJ64989.1 - 1.4e-09 37.5 1.1 4.1e-09 36.0 0.8 1.9 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 CDJ64989.1 - 0.00057 19.9 9.6 0.00057 19.9 6.6 5.7 2 2 3 5 5 5 1 Tuftelin interacting protein N terminal LMBR1 PF04791.11 CDJ64989.1 - 1.3 7.5 1.6 3.1 6.2 1.1 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.4 CDJ64990.1 - 6.2 4.9 32.1 7.9 4.5 22.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAT1 PF09770.4 CDJ64992.1 - 0.84 7.7 90.4 1.3 7.1 14.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 CDJ64992.1 - 1.5 7.3 8.5 0.041 12.4 1.1 2.0 2 1 0 2 2 2 0 LMBR1-like membrane protein TatD_DNase PF01026.16 CDJ64993.1 - 3.1e-32 111.7 0.1 5.7e-31 107.6 0.1 2.1 1 1 0 1 1 1 1 TatD related DNase SR-25 PF10500.4 CDJ64993.1 - 0.00033 20.1 12.8 0.1 12.0 2.3 3.0 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 CDJ64993.1 - 0.035 13.8 0.4 0.098 12.3 0.0 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Herpes_IE2_3 PF03361.9 CDJ64994.1 - 0.094 12.0 0.9 0.23 10.7 0.6 1.7 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 DUF3537 PF12056.3 CDJ64994.1 - 6 5.4 11.5 0.012 14.3 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) Peptidase_C6 PF00851.13 CDJ64995.1 - 0.028 13.0 7.3 0.44 9.1 0.4 2.6 2 0 0 2 2 2 0 Helper component proteinase NTF2 PF02136.15 CDJ64997.1 - 3.5e-16 59.6 0.0 3.5e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Ycf1 PF05758.7 CDJ64997.1 - 0.032 11.9 9.2 0.052 11.2 6.4 1.3 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 CDJ64997.1 - 0.39 8.9 18.4 0.7 8.1 12.8 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein YjgP_YjgQ PF03739.9 CDJ64997.1 - 1.3 7.6 3.1 2 7.0 2.1 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family V_ATPase_I PF01496.14 CDJ64997.1 - 4.6 4.9 7.8 7.1 4.3 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tho2 PF11262.3 CDJ64997.1 - 8 5.4 9.9 13 4.6 6.9 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AAA_23 PF13476.1 CDJ64997.1 - 9.3 6.5 18.6 21 5.3 12.9 1.5 1 0 0 1 1 1 0 AAA domain AP2 PF00847.15 CDJ64998.1 - 8.7e-06 25.7 0.2 1.7e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 AP2 domain C2 PF00168.25 CDJ64999.1 - 9.7e-26 89.4 0.0 1e-06 28.4 0.0 6.4 6 0 0 6 6 6 5 C2 domain FerI PF08151.7 CDJ64999.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 FerI (NUC094) domain Adaptin_binding PF10199.4 CDJ65000.1 - 0.019 15.2 0.3 0.034 14.4 0.2 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 ERM PF00769.14 CDJ65000.1 - 0.019 14.4 11.0 0.03 13.8 7.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HOOK PF05622.7 CDJ65000.1 - 0.042 11.6 11.0 0.06 11.1 7.6 1.1 1 0 0 1 1 1 0 HOOK protein TBPIP PF07106.8 CDJ65000.1 - 0.1 12.1 5.6 0.17 11.4 3.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pyr_redox_2 PF07992.9 CDJ65002.1 - 5.5e-38 130.8 7.7 4.5e-37 127.9 5.3 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CDJ65002.1 - 3e-35 120.5 0.4 9.8e-35 118.9 0.0 2.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CDJ65002.1 - 4.2e-24 84.7 5.8 4.8e-21 74.9 0.4 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CDJ65002.1 - 4.2e-12 45.8 1.5 1.7e-10 40.5 0.6 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CDJ65002.1 - 2.6e-10 40.7 0.3 4.2e-05 23.6 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDJ65002.1 - 3.9e-08 32.1 4.9 0.00024 19.7 0.1 3.9 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.17 CDJ65002.1 - 2.4e-07 29.9 7.0 6.8e-07 28.4 2.0 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 CDJ65002.1 - 5e-07 28.9 11.2 0.0066 15.4 0.1 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDJ65002.1 - 8.5e-07 28.1 3.8 8.5e-07 28.1 2.6 3.3 5 0 0 5 5 5 1 FAD binding domain FAD_binding_3 PF01494.14 CDJ65002.1 - 5.2e-06 25.7 9.3 0.07 12.1 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain K_oxygenase PF13434.1 CDJ65002.1 - 1e-05 24.6 0.6 0.045 12.6 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CDJ65002.1 - 3.1e-05 23.9 7.8 0.0012 18.8 0.9 2.7 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CDJ65002.1 - 7.6e-05 21.9 4.2 0.00022 20.3 0.9 2.9 2 1 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 CDJ65002.1 - 0.0063 16.0 2.2 0.078 12.5 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CDJ65002.1 - 0.017 14.7 0.1 0.017 14.7 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CDJ65002.1 - 0.34 11.1 1.5 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 CDJ65002.1 - 2.6 6.8 6.2 0.96 8.2 0.5 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Abhydrolase_5 PF12695.2 CDJ65003.1 - 7.2e-18 64.7 0.1 9.2e-18 64.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ65003.1 - 2.3e-14 53.8 0.0 5.1e-10 39.6 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDJ65003.1 - 9.3e-08 31.5 0.2 0.0042 16.3 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 CDJ65003.1 - 2.8e-06 26.9 0.2 6.8e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 CDJ65003.1 - 0.00088 18.8 0.0 0.0022 17.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PhoPQ_related PF10142.4 CDJ65003.1 - 0.0027 16.2 0.0 0.0057 15.1 0.0 1.4 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_3 PF07859.8 CDJ65003.1 - 0.0095 15.5 0.9 0.033 13.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 CDJ65003.1 - 0.03 13.2 0.1 0.27 10.1 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme VirJ PF06057.6 CDJ65003.1 - 0.049 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Peptidase_S9_N PF02897.10 CDJ65004.1 - 1.8e-105 352.9 0.1 2.4e-105 352.5 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CDJ65004.1 - 1.9e-58 197.2 0.0 3.1e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDJ65004.1 - 0.0003 20.5 0.1 0.00078 19.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ65004.1 - 0.024 14.2 0.4 0.054 13.0 0.3 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF4227 PF14004.1 CDJ65004.1 - 0.028 14.2 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) Abhydrolase_3 PF07859.8 CDJ65004.1 - 0.032 13.8 0.1 0.097 12.2 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CDJ65004.1 - 0.051 13.4 0.4 0.26 11.1 0.3 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 CDJ65004.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal TPR_MLP1_2 PF07926.7 CDJ65007.1 - 8.9e-05 22.2 12.8 8.9e-05 22.2 8.8 6.3 2 1 2 4 4 4 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 CDJ65007.1 - 0.0018 17.9 17.0 0.0018 17.9 11.8 6.3 1 1 4 5 5 5 2 IncA protein TBPIP PF07106.8 CDJ65007.1 - 0.002 17.7 3.4 0.002 17.7 2.4 7.1 3 2 4 7 7 7 3 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 CDJ65007.1 - 0.0072 16.0 9.2 0.0072 16.0 6.3 7.5 4 2 3 7 7 7 2 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.7 CDJ65007.1 - 0.19 11.5 24.5 0.17 11.7 0.9 4.6 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CDJ65007.1 - 1 8.4 28.5 0.59 9.2 2.1 4.9 1 1 2 5 5 5 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 CDJ65007.1 - 2.6 8.3 33.7 9.3 6.5 0.3 8.0 6 2 1 7 7 7 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 CDJ65007.1 - 7.9 5.6 79.2 0.26 10.4 12.6 5.1 3 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 CDJ65007.1 - 8.1 3.9 87.5 0.45 8.1 16.1 3.3 1 1 2 3 3 3 0 AAA domain PUA PF01472.15 CDJ65009.1 - 5.3e-15 54.8 0.0 7.4e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 PUA domain S10_plectin PF03501.10 CDJ65010.1 - 1.9e-40 136.6 0.3 2.3e-40 136.3 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.4 CDJ65010.1 - 0.096 12.6 0.7 0.13 12.1 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) zf-CCCH PF00642.19 CDJ65011.1 - 6.9e-09 35.1 19.6 2.5e-05 23.8 1.3 3.5 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 CDJ65011.1 - 0.86 9.1 8.7 0.95 8.9 0.4 3.1 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 CDJ65011.1 - 5.8 7.0 15.1 1.2 9.2 0.5 3.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Aldedh PF00171.17 CDJ65012.1 - 0.00034 19.0 0.3 0.0032 15.8 0.0 2.4 2 1 0 3 3 3 1 Aldehyde dehydrogenase family RF-1 PF00472.15 CDJ65013.1 - 1.3e-32 111.9 0.6 1.3e-32 111.9 0.4 2.8 4 0 0 4 4 4 1 RF-1 domain PCRF PF03462.13 CDJ65013.1 - 7.1e-18 64.4 1.7 1.9e-17 63.0 0.3 2.5 2 1 0 2 2 2 1 PCRF domain PspB PF06667.7 CDJ65014.1 - 0.62 10.0 3.2 2.8 7.9 2.2 2.2 1 0 0 1 1 1 0 Phage shock protein B Macoilin PF09726.4 CDJ65015.1 - 1 7.5 6.0 1.4 7.1 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Prefoldin_2 PF01920.15 CDJ65020.1 - 0.0029 17.3 0.0 0.0034 17.1 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit MAGE_N PF12440.3 CDJ65020.1 - 0.044 14.0 0.6 0.044 14.0 0.4 1.5 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Sipho_Gp37 PF14594.1 CDJ65021.1 - 0.037 13.2 0.3 0.073 12.3 0.2 1.5 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein Adeno_E3_CR2 PF02439.10 CDJ65023.1 - 1.2 8.7 3.9 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 IRK PF01007.15 CDJ65024.1 - 1.1e-07 31.0 0.0 0.00022 20.1 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CDJ65024.1 - 0.012 15.3 0.6 0.023 14.3 0.4 1.4 1 0 0 1 1 1 0 Ion channel Filament PF00038.16 CDJ65028.1 - 0.01 15.3 4.5 0.013 15.0 3.1 1.0 1 0 0 1 1 1 0 Intermediate filament protein Leu_zip PF15294.1 CDJ65028.1 - 0.012 14.7 5.8 0.014 14.5 4.0 1.1 1 0 0 1 1 1 0 Leucine zipper GAS PF13851.1 CDJ65028.1 - 0.014 14.6 7.0 0.019 14.1 4.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ead_Ea22 PF13935.1 CDJ65028.1 - 0.024 14.9 2.0 0.028 14.7 1.4 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF3683 PF12447.3 CDJ65028.1 - 0.13 12.1 0.1 0.13 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) Spc7 PF08317.6 CDJ65028.1 - 0.22 10.1 4.5 0.23 10.0 3.1 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Dermcidin PF15291.1 CDJ65028.1 - 0.22 11.7 1.3 0.27 11.4 0.9 1.1 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide DUF1151 PF06625.6 CDJ65028.1 - 0.27 10.9 7.0 0.33 10.6 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) ADIP PF11559.3 CDJ65028.1 - 0.34 10.7 5.7 0.45 10.4 3.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CDJ65028.1 - 0.71 10.2 5.8 1.8 8.9 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TPD52 PF04201.10 CDJ65028.1 - 0.71 9.5 5.0 0.79 9.4 3.4 1.2 1 0 0 1 1 1 0 Tumour protein D52 family IncA PF04156.9 CDJ65028.1 - 1 8.9 5.1 1.1 8.8 3.5 1.1 1 0 0 1 1 1 0 IncA protein UVR PF02151.14 CDJ65028.1 - 1.1 8.8 5.7 0.48 10.0 1.6 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif DUF724 PF05266.9 CDJ65028.1 - 1.3 8.5 6.4 1.5 8.3 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.1 CDJ65028.1 - 3.3 7.7 8.3 1.6 8.7 4.1 1.6 1 1 0 1 1 1 0 FlxA-like protein DUF904 PF06005.7 CDJ65028.1 - 4.4 7.6 9.2 1.1 9.5 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IFP_35_N PF07334.8 CDJ65028.1 - 5.2 7.1 11.7 10 6.2 0.2 2.9 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DegS PF05384.6 CDJ65029.1 - 0.027 13.6 4.6 0.054 12.7 3.2 1.6 1 1 0 1 1 1 0 Sensor protein DegS FlbT PF07378.6 CDJ65029.1 - 0.07 12.9 1.0 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 Flagellar protein FlbT PMT_C PF11647.3 CDJ65029.1 - 0.073 12.6 4.9 19 4.9 0.0 3.4 3 0 0 3 3 3 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 APG6 PF04111.7 CDJ65029.1 - 0.23 10.4 14.6 0.069 12.1 7.9 1.6 1 1 1 2 2 2 0 Autophagy protein Apg6 GAS PF13851.1 CDJ65029.1 - 0.26 10.4 16.1 0.05 12.7 7.4 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Microtub_bind PF13931.1 CDJ65029.1 - 0.28 11.3 5.5 0.39 10.8 3.8 1.2 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding PLAC9 PF15205.1 CDJ65029.1 - 0.72 10.1 2.7 0.65 10.3 0.2 2.0 2 0 0 2 2 2 0 Placenta-specific protein 9 Fes1 PF08609.5 CDJ65029.1 - 1.2 9.7 5.0 16 6.0 0.2 2.5 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Phage_GP20 PF06810.6 CDJ65029.1 - 2.2 7.6 11.2 0.34 10.3 3.3 2.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 Med9 PF07544.8 CDJ65029.1 - 4.6 7.0 9.1 2.1 8.1 2.9 2.8 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.1 CDJ65030.1 - 0.019 13.4 27.0 0.025 13.0 18.7 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 CDJ65030.1 - 0.06 12.2 45.5 0.011 14.7 22.7 2.4 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Bacillus_HBL PF05791.6 CDJ65030.1 - 0.27 10.5 24.4 2.2 7.6 10.0 2.9 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Nup54 PF13874.1 CDJ65030.1 - 0.52 9.9 42.4 0.099 12.3 12.5 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 EzrA PF06160.7 CDJ65030.1 - 0.53 8.4 32.7 0.67 8.0 22.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Erp_C PF06780.6 CDJ65030.1 - 0.72 9.6 18.1 0.26 11.1 2.8 2.3 1 1 1 2 2 2 0 Erp protein C-terminus ARGLU PF15346.1 CDJ65030.1 - 1 9.1 51.2 1.9 8.2 22.1 2.2 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 Reo_sigmaC PF04582.7 CDJ65030.1 - 1.7 7.7 11.1 3.3 6.8 2.3 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Spc7 PF08317.6 CDJ65030.1 - 1.8 7.1 37.9 0.41 9.2 18.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.1 CDJ65030.1 - 2 7.5 41.4 3.6 6.7 15.1 2.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Ribonucleas_3_2 PF11469.3 CDJ65030.1 - 2.1 8.5 6.6 9.9 6.3 0.4 2.4 1 1 0 2 2 2 0 Ribonuclease III ADIP PF11559.3 CDJ65030.1 - 2.1 8.2 48.2 0.24 11.2 15.5 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 CDJ65030.1 - 3.4 5.9 24.2 5 5.4 16.5 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF812 PF05667.6 CDJ65030.1 - 4 5.8 31.3 5.8 5.2 21.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Rrn6 PF10214.4 CDJ65030.1 - 6.9 4.6 20.4 8.4 4.3 14.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor E2R135 PF11570.3 CDJ65030.1 - 8.4 6.4 24.9 0.6 10.1 4.1 3.0 1 1 2 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 DUF1664 PF07889.7 CDJ65030.1 - 8.7 6.1 20.9 4.7 7.0 1.5 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Med15 PF09606.5 CDJ65030.1 - 8.9 4.3 24.0 9.6 4.2 16.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2433 PF10360.4 CDJ65030.1 - 8.9 6.6 7.7 3.4 7.9 0.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2433) RRM_1 PF00076.17 CDJ65032.1 - 1.6e-28 98.1 0.0 1.5e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ65032.1 - 1.7e-18 66.3 0.0 2.8e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ65032.1 - 1.1e-07 31.5 0.1 8.4e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_viral_N PF00242.12 CDJ65032.1 - 5 6.0 23.8 0.39 9.6 4.8 2.1 1 1 1 2 2 2 0 DNA polymerase (viral) N-terminal domain Pkinase PF00069.20 CDJ65033.1 - 8.1e-53 179.2 0.0 3.2e-52 177.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65033.1 - 1.5e-37 129.0 0.0 2.1e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ65033.1 - 4.9e-09 35.5 0.0 8.7e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Dynein_heavy PF03028.10 CDJ65034.1 - 0.0007 17.7 0.1 0.0007 17.7 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 CDJ65035.1 - 2.9e-56 190.6 3.1 4.8e-56 189.9 2.1 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CDJ65035.1 - 1.7e-25 89.1 0.0 1.1e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDJ65035.1 - 6.1e-24 84.4 0.0 1.8e-22 79.6 0.0 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.10 CDJ65035.1 - 3.4e-17 61.7 2.4 7.5e-17 60.6 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_7 PF12775.2 CDJ65035.1 - 4.1e-13 49.0 0.0 3.6e-06 26.2 0.0 3.0 2 1 1 3 3 3 2 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDJ65035.1 - 0.00069 19.3 0.7 1 9.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CDJ65035.1 - 0.0055 16.8 4.7 2.5 8.2 0.0 4.5 3 1 1 4 4 4 2 AAA domain AAA_6 PF12774.2 CDJ65035.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 PRK PF00485.13 CDJ65035.1 - 0.35 10.4 0.9 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_13 PF13166.1 CDJ65035.1 - 1.1 7.6 9.8 1.4 7.2 0.4 2.2 2 0 0 2 2 2 0 AAA domain DHC_N2 PF08393.8 CDJ65036.1 - 1.3e-86 290.7 1.3 1.7e-86 290.3 0.2 1.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDJ65036.1 - 2.7e-69 233.2 0.1 5.6e-69 232.1 0.1 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CDJ65036.1 - 0.00046 19.9 0.0 0.0082 15.8 0.0 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF4510 PF14971.1 CDJ65036.1 - 0.0037 17.4 1.9 0.0037 17.4 1.3 4.2 5 1 0 5 5 5 1 Domain of unknown function (DUF4510) AAA PF00004.24 CDJ65036.1 - 0.017 15.3 0.0 0.059 13.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CDJ65036.1 - 0.028 15.2 0.1 0.37 11.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain THOC7 PF05615.8 CDJ65036.1 - 0.31 11.3 8.1 0.91 9.7 2.9 3.4 2 1 0 2 2 2 0 Tho complex subunit 7 HsbA PF12296.3 CDJ65036.1 - 0.97 9.3 4.3 4.2 7.2 0.2 3.2 3 0 0 3 3 3 0 Hydrophobic surface binding protein A DUF2205 PF10224.4 CDJ65036.1 - 1.1 8.8 5.7 2.3 7.8 0.2 3.4 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) Baculo_PEP_C PF04513.7 CDJ65036.1 - 6.5 6.5 9.1 28 4.5 0.2 4.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4613 PF15390.1 CDJ65038.1 - 2.5 6.1 15.0 3 5.8 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) K_channel_TID PF07941.6 CDJ65040.1 - 0.039 14.1 4.7 0.14 12.4 0.9 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Kin17_mid PF10357.4 CDJ65042.1 - 2.1e-41 140.5 2.8 2.1e-41 140.5 1.9 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein DUF4030 PF13222.1 CDJ65042.1 - 0.0081 15.8 0.1 0.031 14.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4030) zf-met PF12874.2 CDJ65042.1 - 0.0099 16.0 3.6 0.0099 16.0 2.5 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDJ65042.1 - 0.18 11.9 8.1 0.084 13.0 3.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rick_17kDa_Anti PF05433.10 CDJ65044.1 - 0.073 12.7 0.4 0.14 11.7 0.3 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Clat_adaptor_s PF01217.15 CDJ65045.1 - 2.2e-09 37.1 0.0 4.7e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Hydrolase_4 PF12146.3 CDJ65046.1 - 4.7e-10 39.1 0.3 2.2e-06 27.3 0.1 2.5 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_5 PF12695.2 CDJ65046.1 - 3e-09 36.7 0.0 3e-09 36.7 0.0 2.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF726 PF05277.7 CDJ65046.1 - 0.1 11.4 0.1 0.1 11.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF726) Med15 PF09606.5 CDJ65049.1 - 0.002 16.4 23.3 0.0023 16.2 16.2 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc1_Nup PF09531.5 CDJ65049.1 - 0.24 9.7 11.5 0.34 9.2 8.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.10 CDJ65049.1 - 0.26 9.9 12.4 0.0051 15.5 4.0 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDJ65049.1 - 0.52 7.9 12.6 0.7 7.5 8.7 1.1 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 CDJ65049.1 - 1.1 8.7 15.8 1.9 7.9 10.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Hid1 PF12722.2 CDJ65049.1 - 1.8 6.1 17.0 2.2 5.8 11.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Fmp27_WPPW PF10359.4 CDJ65049.1 - 1.9 6.8 15.8 2.8 6.2 10.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DNA_pol_viral_N PF00242.12 CDJ65049.1 - 3.1 6.7 16.5 5.5 5.9 11.4 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CDC45 PF02724.9 CDJ65049.1 - 4.9 5.0 20.6 7.3 4.5 14.3 1.2 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 CDJ65049.1 - 5.1 5.8 14.8 9 5.0 10.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TFIIA PF03153.8 CDJ65049.1 - 6.9 6.4 32.7 10 5.9 22.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.14 CDJ65049.1 - 7.7 6.2 18.4 15 5.3 12.8 1.4 1 0 0 1 1 1 0 SPX domain UCH PF00443.24 CDJ65050.1 - 0.2 10.7 1.5 0.38 9.8 1.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4463 PF14703.1 CDJ65051.1 - 0.11 13.0 0.5 0.54 10.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Macoilin PF09726.4 CDJ65051.1 - 2.2 6.4 44.6 0.65 8.2 14.9 2.3 2 0 0 2 2 2 0 Transmembrane protein Iso_dh PF00180.15 CDJ65052.1 - 6.5e-22 77.9 0.0 7.3e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 CDJ65053.1 - 8.5e-42 143.3 0.0 9.8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phosphorylase PF00343.15 CDJ65054.1 - 0 1010.7 0.0 0 1010.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase EGF_CA PF07645.10 CDJ65055.1 - 6.4e-214 691.8 539.0 1.3e-11 44.2 8.3 34.3 31 2 1 32 32 32 27 Calcium-binding EGF domain EGF_3 PF12947.2 CDJ65055.1 - 1.2e-149 485.8 532.1 4.2e-10 39.4 11.2 33.1 31 1 1 32 32 32 29 EGF domain cEGF PF12662.2 CDJ65055.1 - 1e-138 450.2 305.1 8.4e-09 34.9 2.0 32.3 32 0 0 32 32 32 27 Complement Clr-like EGF-like EGF PF00008.22 CDJ65055.1 - 1.7e-79 261.1 426.8 7.5e-06 25.8 4.3 32.6 30 1 2 32 32 32 29 EGF-like domain EGF_MSP1_1 PF12946.2 CDJ65055.1 - 9.4e-40 134.1 374.6 5.5e-07 29.2 4.8 32.4 32 0 0 32 32 32 24 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CDJ65055.1 - 6.4e-24 83.7 500.6 0.00017 21.6 7.1 32.2 29 4 3 32 32 32 23 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CDJ65055.1 - 9.8e-11 41.0 183.8 0.43 10.7 0.8 30.7 30 0 0 30 30 30 14 Human growth factor-like EGF HTH_20 PF12840.2 CDJ65055.1 - 0.86 9.4 0.6 90 2.9 0.0 3.8 4 0 0 4 4 4 0 Helix-turn-helix domain DUF3530 PF12048.3 CDJ65055.1 - 9 5.1 2.3 13 4.6 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) C2 PF00168.25 CDJ65057.1 - 6e-33 112.5 0.0 4.5e-12 45.6 0.0 4.7 4 0 0 4 4 4 4 C2 domain SF3b1 PF08920.5 CDJ65058.1 - 1.2e-31 109.7 6.5 9.9e-28 97.0 0.1 2.9 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CDJ65058.1 - 9.6e-12 45.0 5.3 0.0091 16.2 0.0 7.1 5 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 CDJ65058.1 - 2e-07 31.3 3.4 0.19 12.2 0.0 6.8 6 2 3 9 9 9 2 HEAT-like repeat HEAT PF02985.17 CDJ65058.1 - 8.3e-06 25.4 14.5 1.5 9.0 0.1 8.2 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.15 CDJ65058.1 - 1.6e-05 23.4 0.2 0.03 12.6 0.0 3.5 3 1 0 3 3 3 2 Adaptin N terminal region Arm PF00514.18 CDJ65058.1 - 0.00038 20.1 2.5 6.3 6.7 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat UME PF08064.8 CDJ65058.1 - 0.00082 19.2 0.6 0.65 9.9 0.0 3.9 4 0 0 4 4 4 1 UME (NUC010) domain CLASP_N PF12348.3 CDJ65058.1 - 0.042 13.1 0.0 1.4 8.2 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal Cnd3 PF12719.2 CDJ65058.1 - 0.11 11.4 0.1 2.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Hamartin PF04388.7 CDJ65058.1 - 8.5 4.9 8.0 0.97 8.0 0.7 2.1 2 0 0 2 2 2 0 Hamartin protein Myb_DNA-binding PF00249.26 CDJ65059.1 - 9.5e-07 28.7 1.9 0.008 16.2 0.0 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDJ65059.1 - 0.0052 16.8 0.1 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Gly-zipper_OmpA PF13436.1 CDJ65060.1 - 1.7 8.3 17.6 0.14 11.7 7.9 2.5 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain START PF01852.14 CDJ65062.1 - 1.3e-13 50.7 0.0 1.7e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 START domain SAPS PF04499.10 CDJ65063.1 - 0.015 13.9 4.4 0.018 13.7 3.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.8 CDJ65063.1 - 0.015 15.2 28.9 0.019 14.9 20.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehalogenase PF13486.1 CDJ65063.1 - 0.071 12.5 5.4 3.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Reductive dehalogenase subunit FNIP_M PF14637.1 CDJ65063.1 - 0.074 12.6 0.0 0.074 12.6 0.0 1.8 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain DUF2052 PF09747.4 CDJ65063.1 - 1 9.2 13.9 3.9 7.3 7.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PLRV_ORF5 PF01690.12 CDJ65063.1 - 4.7 6.2 20.2 6.4 5.8 14.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PRAP PF15314.1 CDJ65063.1 - 8.5 6.7 7.2 20 5.5 5.0 1.6 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine SR-25 PF10500.4 CDJ65064.1 - 0.0012 18.3 10.1 0.0012 18.3 7.0 4.2 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein DUF998 PF06197.8 CDJ65064.1 - 0.33 10.2 14.6 0.027 13.7 4.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) TLP-20 PF06088.6 CDJ65064.1 - 2 8.0 9.8 0.96 9.0 2.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HVSL PF09749.4 CDJ65065.1 - 5.6e-26 91.0 23.8 7.8e-19 67.6 11.7 3.6 2 1 1 3 3 3 2 Uncharacterised conserved protein Pox_Ag35 PF03286.9 CDJ65065.1 - 0.0054 16.2 1.1 0.0054 16.2 0.8 3.3 2 1 1 3 3 3 1 Pox virus Ag35 surface protein PAT1 PF09770.4 CDJ65065.1 - 1.5 6.9 119.0 0.35 9.0 22.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PMI_typeI PF01238.16 CDJ65066.1 - 7.5e-32 110.7 37.0 1.4e-18 66.9 19.6 2.9 1 1 1 2 2 2 2 Phosphomannose isomerase type I HEAT_EZ PF13513.1 CDJ65066.1 - 1.5 9.4 7.7 7.2 7.2 0.5 3.4 2 1 0 2 2 2 0 HEAT-like repeat UBA PF00627.26 CDJ65067.1 - 2.4e-08 33.5 0.1 4.6e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 CDJ65067.1 - 0.002 17.5 0.4 0.005 16.3 0.0 1.7 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.1 CDJ65067.1 - 0.022 14.2 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 UBA-like domain GrpE PF01025.14 CDJ65068.1 - 0.0022 17.5 4.2 0.0028 17.2 2.9 1.1 1 0 0 1 1 1 1 GrpE DUF2361 PF10153.4 CDJ65068.1 - 0.0031 17.6 2.1 0.0034 17.5 1.4 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2361) DUF4065 PF13274.1 CDJ65068.1 - 0.006 17.2 1.9 0.0098 16.5 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4065) DUF2115 PF09888.4 CDJ65068.1 - 0.0084 16.2 1.4 0.011 15.7 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2115) RRN3 PF05327.6 CDJ65068.1 - 0.015 13.4 0.5 0.017 13.2 0.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4163 PF13739.1 CDJ65068.1 - 0.015 16.0 5.6 0.026 15.2 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) PMC2NT PF08066.7 CDJ65068.1 - 0.024 14.9 1.2 0.14 12.4 0.2 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain UPF0147 PF03685.8 CDJ65068.1 - 0.025 14.4 0.5 0.038 13.8 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) DUF3086 PF11285.3 CDJ65068.1 - 0.027 13.2 1.2 0.032 13.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) IcmF-related PF06761.7 CDJ65068.1 - 0.03 13.6 0.3 0.035 13.3 0.2 1.1 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing DUF935 PF06074.7 CDJ65068.1 - 0.039 12.6 2.9 0.045 12.4 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF883 PF05957.8 CDJ65068.1 - 0.045 14.1 1.3 0.51 10.7 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Z1 PF10593.4 CDJ65068.1 - 0.096 11.8 5.2 0.13 11.4 3.6 1.3 1 1 0 1 1 1 0 Z1 domain HSCB_C PF07743.8 CDJ65068.1 - 0.1 13.0 5.1 0.14 12.6 2.4 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4407 PF14362.1 CDJ65068.1 - 0.11 11.4 4.0 0.16 10.8 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kinetochor_Ybp2 PF08568.5 CDJ65068.1 - 0.13 10.4 2.8 0.17 10.1 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin DUF3490 PF11995.3 CDJ65068.1 - 0.16 11.5 2.2 0.18 11.3 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) pRN1_helical PF13010.1 CDJ65068.1 - 0.18 11.4 7.8 0.25 10.9 5.4 1.2 1 0 0 1 1 1 0 Primase helical domain Phage_Gp23 PF10669.4 CDJ65068.1 - 0.29 11.2 4.5 0.47 10.5 3.1 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF106 PF01956.11 CDJ65068.1 - 0.37 10.3 1.5 0.4 10.1 1.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 HIT PF01230.18 CDJ65068.1 - 0.82 10.2 2.7 2.6 8.6 1.1 2.0 1 1 1 2 2 2 0 HIT domain DUF4047 PF13256.1 CDJ65068.1 - 2.5 8.0 10.0 13 5.7 5.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Apt1 PF10351.4 CDJ65069.1 - 0.0021 17.0 3.6 0.0027 16.6 2.5 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain OPT PF03169.10 CDJ65069.1 - 0.006 15.0 0.0 0.009 14.4 0.0 1.3 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAM60A PF15396.1 CDJ65069.1 - 0.0096 15.6 9.0 0.013 15.2 6.3 1.3 1 0 0 1 1 1 1 Protein Family FAM60A Gti1_Pac2 PF09729.4 CDJ65069.1 - 0.014 15.2 3.7 0.018 14.9 2.6 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Hid1 PF12722.2 CDJ65069.1 - 0.018 12.7 10.1 0.016 12.9 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDJ65069.1 - 0.02 12.6 8.4 0.019 12.6 5.8 1.1 1 0 0 1 1 1 0 Ycf1 CD20 PF04103.10 CDJ65069.1 - 0.025 14.4 14.7 4.2 7.2 6.3 3.1 1 1 1 2 2 2 0 CD20-like family Patched PF02460.13 CDJ65069.1 - 0.031 12.2 0.1 0.036 11.9 0.1 1.1 1 0 0 1 1 1 0 Patched family Exonuc_VII_L PF02601.10 CDJ65069.1 - 0.04 13.1 20.0 0.047 12.8 13.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nucleoside_tran PF01733.13 CDJ65069.1 - 0.041 13.0 4.4 0.059 12.5 3.1 1.2 1 0 0 1 1 1 0 Nucleoside transporter Plasmodium_Vir PF05795.6 CDJ65069.1 - 0.062 12.5 0.2 0.07 12.3 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Shadoo PF14999.1 CDJ65069.1 - 0.1 12.4 23.7 0.21 11.4 4.8 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective CRT10 PF08728.5 CDJ65069.1 - 0.11 10.4 4.5 0.11 10.5 3.1 1.0 1 0 0 1 1 1 0 CRT10 Peptidase_S15 PF02129.13 CDJ65069.1 - 0.17 11.2 22.2 0.021 14.2 12.2 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Mem_trans PF03547.13 CDJ65069.1 - 0.17 10.1 2.5 0.23 9.7 1.8 1.3 1 0 0 1 1 1 0 Membrane transport protein GAGA_bind PF06217.7 CDJ65069.1 - 0.19 11.6 17.1 0.2 11.6 11.5 1.3 1 1 0 1 1 1 0 GAGA binding protein-like family PBP1_TM PF14812.1 CDJ65069.1 - 0.2 12.0 8.5 0.34 11.2 5.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-3_zeta PF05091.7 CDJ65069.1 - 0.34 9.4 21.9 0.47 9.0 15.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) YjgP_YjgQ PF03739.9 CDJ65069.1 - 0.39 9.3 8.5 0.5 9.0 5.9 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RR_TM4-6 PF06459.7 CDJ65069.1 - 0.48 10.2 14.4 0.81 9.5 10.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIF4E-T PF10477.4 CDJ65069.1 - 0.59 8.8 14.3 0.75 8.5 9.9 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF588 PF04535.7 CDJ65069.1 - 0.8 9.2 16.9 0.11 12.0 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF588) HCO3_cotransp PF00955.16 CDJ65069.1 - 0.9 8.1 3.0 1 7.9 2.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF3381 PF11861.3 CDJ65069.1 - 0.92 8.9 17.6 1.5 8.3 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF912 PF06024.7 CDJ65069.1 - 1.1 9.3 13.0 7.5 6.6 8.8 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HlyD_2 PF12700.2 CDJ65069.1 - 1.2 8.1 11.8 1.3 8.1 8.2 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Endonuc_Holl PF10107.4 CDJ65069.1 - 1.4 8.6 18.1 0.77 9.4 11.2 1.7 2 0 0 2 2 1 0 Endonuclease related to archaeal Holliday junction resolvase Paramyxo_ncap PF00973.14 CDJ65069.1 - 1.6 7.3 12.0 2.3 6.8 8.3 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SID-1_RNA_chan PF13965.1 CDJ65069.1 - 1.7 6.6 7.2 2.2 6.3 5.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 YfhO PF09586.5 CDJ65069.1 - 1.7 6.5 7.3 1.8 6.4 5.1 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Band_3_cyto PF07565.8 CDJ65069.1 - 1.8 7.9 22.2 0.48 9.9 13.5 1.4 2 0 0 2 2 1 0 Band 3 cytoplasmic domain LMBR1 PF04791.11 CDJ65069.1 - 2.2 6.7 9.3 2.6 6.5 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Anoctamin PF04547.7 CDJ65069.1 - 2.3 6.7 14.1 4.5 5.8 9.7 1.5 1 1 0 1 1 1 0 Calcium-activated chloride channel Ribosomal_60s PF00428.14 CDJ65069.1 - 2.3 8.6 38.7 1.5 9.2 11.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3675 PF12428.3 CDJ65069.1 - 2.4 8.4 12.5 1.1 9.5 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) Peptidase_U57 PF05582.7 CDJ65069.1 - 2.7 6.8 12.4 4.3 6.2 8.6 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Baculo_PP31 PF05311.6 CDJ65069.1 - 3.1 6.9 15.8 4.5 6.4 11.0 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Glyco_transf_15 PF01793.11 CDJ65069.1 - 3.4 6.5 14.5 5.2 5.9 10.0 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF2347 PF09804.4 CDJ65069.1 - 4.7 6.3 10.3 6.6 5.9 7.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) FLO_LFY PF01698.11 CDJ65069.1 - 5 5.8 18.8 8.6 5.0 13.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Topoisom_I_N PF02919.10 CDJ65069.1 - 5.9 6.1 12.1 8.4 5.6 8.4 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DDHD PF02862.12 CDJ65069.1 - 8.3 6.1 19.4 0.66 9.7 10.1 1.6 2 0 0 2 2 2 0 DDHD domain Dehalogenase PF13486.1 CDJ65069.1 - 10 5.4 12.0 13 5.1 7.9 1.4 1 1 0 1 1 1 0 Reductive dehalogenase subunit N_NLPC_P60 PF12912.2 CDJ65070.1 - 0.0055 16.7 0.9 0.0066 16.5 0.6 1.1 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term dsDNA_bind PF01984.15 CDJ65070.1 - 0.026 14.5 5.4 0.028 14.3 3.7 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain DUF620 PF04788.7 CDJ65070.1 - 0.029 13.5 0.1 0.032 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF620) ATP-synt_E PF05680.7 CDJ65070.1 - 0.035 14.0 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 ATP synthase E chain DUF2076 PF09849.4 CDJ65070.1 - 0.041 13.9 4.4 0.044 13.8 3.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RAB3GAP2_N PF14655.1 CDJ65070.1 - 0.051 12.5 0.6 0.051 12.5 0.4 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med3 PF11593.3 CDJ65070.1 - 0.06 12.5 6.8 0.072 12.3 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.3 CDJ65070.1 - 0.072 12.4 0.6 0.07 12.4 0.4 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.11 CDJ65070.1 - 0.31 9.8 3.7 0.31 9.8 2.6 1.1 1 0 0 1 1 1 0 Androgen receptor BAF1_ABF1 PF04684.8 CDJ65070.1 - 5.3 5.7 7.5 5.3 5.7 5.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_M3 PF01432.15 CDJ65072.1 - 1.7e-11 43.8 0.0 3.6e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 MFS_2 PF13347.1 CDJ65073.1 - 0.077 11.3 0.4 0.089 11.1 0.3 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein CDC50 PF03381.10 CDJ65074.1 - 9.9e-19 67.5 0.0 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Herpes_LMP1 PF05297.6 CDJ65074.1 - 0.037 12.9 1.3 0.07 12.0 0.9 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2207 PF09972.4 CDJ65075.1 - 0.0025 16.4 0.0 0.0035 15.9 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 CDJ65075.1 - 0.0036 16.7 3.0 0.004 16.6 2.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Glyco_trans_2_3 PF13632.1 CDJ65075.1 - 0.039 13.6 5.0 0.043 13.5 3.5 1.1 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Pex16 PF08610.5 CDJ65075.1 - 0.16 10.9 1.5 0.18 10.7 1.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) MMPL PF03176.10 CDJ65075.1 - 0.28 9.8 3.0 0.44 9.1 2.0 1.3 1 1 0 1 1 1 0 MMPL family PHD_3 PF13922.1 CDJ65075.1 - 0.29 11.4 2.3 0.4 10.9 1.6 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx GN3L_Grn1 PF08701.6 CDJ65075.1 - 0.5 10.2 5.2 0.69 9.8 3.6 1.1 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase CobD_Cbib PF03186.8 CDJ65075.1 - 0.75 8.8 3.9 1.1 8.2 2.7 1.3 1 0 0 1 1 1 0 CobD/Cbib protein SR-25 PF10500.4 CDJ65076.1 - 0.012 15.0 10.3 0.012 15.0 7.1 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein P12 PF12669.2 CDJ65077.1 - 0.33 11.1 13.7 0.84 9.8 9.5 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family Acyl-thio_N PF12590.3 CDJ65078.1 - 0.24 11.8 2.6 0.27 11.6 1.0 1.6 1 1 0 1 1 1 0 Acyl-ATP thioesterase Ribosomal_60s PF00428.14 CDJ65078.1 - 0.99 9.8 10.0 0.047 14.0 0.9 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein RNA_pol_Rpb1_2 PF00623.15 CDJ65079.1 - 9.1e-45 152.5 0.2 1.7e-27 96.4 0.0 3.0 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 CDJ65079.1 - 5.5e-15 55.4 5.7 3.6e-13 49.4 0.0 4.0 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 CDJ65079.1 - 3.8e-14 52.6 0.0 8.9e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 3 SieB PF14163.1 CDJ65079.1 - 0.055 13.0 0.3 0.15 11.5 0.2 1.7 1 0 0 1 1 1 0 Superinfection exclusion protein B Med15 PF09606.5 CDJ65079.1 - 1.1 7.3 41.4 0.36 8.9 5.6 3.2 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 CDJ65079.1 - 1.5 8.6 6.2 1.5 8.6 0.1 2.7 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Metal_resist PF13801.1 CDJ65080.1 - 0.021 14.8 7.8 0.021 14.8 5.4 3.2 2 1 1 3 3 3 0 Heavy-metal resistance Peptidase_A24 PF01478.13 CDJ65080.1 - 0.39 10.8 3.5 0.64 10.2 2.4 1.3 1 0 0 1 1 1 0 Type IV leader peptidase family RAB3GAP2_N PF14655.1 CDJ65080.1 - 6.4 5.6 17.1 0.38 9.7 1.6 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3648 PF12364.3 CDJ65081.1 - 0.11 12.4 4.5 0.14 12.1 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) HlyD_2 PF12700.2 CDJ65081.1 - 0.29 10.2 2.0 0.27 10.3 1.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein bZIP_C PF12498.3 CDJ65081.1 - 1.4 10.1 12.7 1.7 9.8 8.8 1.1 1 0 0 1 1 1 0 Basic leucine-zipper C terminal ResIII PF04851.10 CDJ65081.1 - 2.1 8.1 7.5 2.4 7.9 5.2 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4230 PF14014.1 CDJ65081.1 - 3.1 7.6 10.9 4.6 7.0 7.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) Pex14_N PF04695.8 CDJ65081.1 - 3.3 7.7 10.2 4.2 7.4 7.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zein PF01559.11 CDJ65081.1 - 5.3 6.2 30.3 6.5 5.9 21.0 1.2 1 0 0 1 1 1 0 Zein seed storage protein M16C_assoc PF08367.6 CDJ65082.1 - 1.2e-19 70.1 2.5 5.4e-12 45.0 0.0 2.5 1 1 1 2 2 2 2 Peptidase M16C associated Peptidase_M16_C PF05193.16 CDJ65082.1 - 4.5e-06 26.4 5.6 4.6e-05 23.1 0.0 3.9 3 2 0 3 3 3 1 Peptidase M16 inactive domain Med15 PF09606.5 CDJ65083.1 - 0.0016 16.7 13.9 0.0016 16.7 9.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CAF1 PF04857.15 CDJ65083.1 - 0.024 13.9 0.0 0.049 12.9 0.0 1.5 1 1 1 2 2 2 0 CAF1 family ribonuclease CagX PF03524.10 CDJ65083.1 - 0.21 10.8 2.7 0.67 9.1 1.8 1.7 2 0 0 2 2 2 0 Conjugal transfer protein PAT1 PF09770.4 CDJ65083.1 - 1.8 6.7 18.2 2.2 6.4 12.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1645 PF07816.6 CDJ65083.1 - 8.9 6.7 12.2 0.88 9.9 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Pox_Ag35 PF03286.9 CDJ65084.1 - 0.0037 16.8 17.7 0.0043 16.6 12.2 1.0 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF1510 PF07423.6 CDJ65084.1 - 0.77 9.0 30.9 0.87 8.9 21.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CAF-1_p150 PF11600.3 CDJ65084.1 - 1.1 8.6 39.4 1.2 8.4 27.3 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAM60A PF15396.1 CDJ65084.1 - 2.1 8.0 28.5 2.4 7.8 19.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Caldesmon PF02029.10 CDJ65084.1 - 2.6 6.3 26.4 2.9 6.2 18.3 1.0 1 0 0 1 1 1 0 Caldesmon CDC45 PF02724.9 CDJ65084.1 - 3.1 5.7 27.7 3.5 5.5 19.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 CDJ65084.1 - 3.8 6.9 42.8 4.5 6.6 29.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FLO_LFY PF01698.11 CDJ65084.1 - 4.2 6.1 28.1 5.1 5.8 19.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein MRP-S31 PF15433.1 CDJ65084.1 - 5.4 6.3 36.1 5.9 6.2 25.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Rtf2 PF04641.7 CDJ65084.1 - 6.1 5.9 30.1 8.1 5.5 20.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Vfa1 PF08432.5 CDJ65084.1 - 6.5 6.7 31.4 7.9 6.4 21.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpb1_5 PF04998.12 CDJ65084.1 - 6.7 5.8 16.8 8.2 5.6 11.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Utp14 PF04615.8 CDJ65084.1 - 7.3 4.6 37.3 8.2 4.4 25.9 1.0 1 0 0 1 1 1 0 Utp14 protein Exonuc_VII_L PF02601.10 CDJ65084.1 - 7.4 5.6 34.5 9.6 5.2 23.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit AUX_IAA PF02309.11 CDJ65084.1 - 7.8 6.1 27.5 9.2 5.9 19.0 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF4045 PF13254.1 CDJ65084.1 - 8 5.6 31.1 8.4 5.5 21.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ribosomal_60s PF00428.14 CDJ65084.1 - 8.2 6.9 9.7 16 5.9 6.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein CKAP2_C PF15297.1 CDJ65084.1 - 9 4.9 30.2 12 4.6 20.9 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Hid1 PF12722.2 CDJ65084.1 - 9.7 3.7 32.9 11 3.5 22.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NARP1 PF12569.3 CDJ65084.1 - 9.9 4.7 30.2 14 4.2 21.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Activator_LAG-3 PF11498.3 CDJ65085.1 - 1.2e-05 24.2 27.3 1.9e-05 23.6 18.9 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Suf PF05843.9 CDJ65085.1 - 0.0008 19.2 6.7 0.0011 18.7 4.6 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ65085.1 - 0.0034 15.6 27.9 0.0034 15.6 19.3 1.8 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ65085.1 - 0.0063 16.8 14.0 0.0063 16.8 9.7 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein SprA-related PF12118.3 CDJ65085.1 - 0.0067 15.7 16.2 0.0067 15.7 11.2 2.2 2 0 0 2 2 2 1 SprA-related family Dicty_REP PF05086.7 CDJ65085.1 - 0.018 12.8 2.1 0.028 12.2 1.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ExbD PF02472.11 CDJ65085.1 - 0.087 12.8 4.2 0.22 11.5 2.9 1.7 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR PAT1 PF09770.4 CDJ65085.1 - 0.14 10.3 26.1 0.16 10.1 18.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.10 CDJ65085.1 - 0.23 10.1 2.4 0.33 9.6 1.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spore_coat_CotO PF14153.1 CDJ65085.1 - 0.25 10.7 14.9 0.035 13.5 6.0 2.1 2 0 0 2 2 2 0 Spore coat protein CotO RR_TM4-6 PF06459.7 CDJ65085.1 - 0.29 10.9 8.4 0.082 12.7 2.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 OATP PF03137.15 CDJ65085.1 - 1.8 6.5 4.8 2.8 5.9 3.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.8 CDJ65085.1 - 2.5 8.1 17.2 0.3 11.1 8.7 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.1 CDJ65085.1 - 3.4 5.2 30.4 6.4 4.3 21.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RIC3 PF15361.1 CDJ65085.1 - 7.3 6.8 13.1 1.1 9.5 5.7 2.0 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Herpes_DNAp_acc PF04929.7 CDJ65085.1 - 7.6 5.3 9.9 12 4.7 6.9 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor NIF PF03031.13 CDJ65086.1 - 8.2e-25 87.3 0.0 3e-13 49.7 0.0 3.0 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase BAF1_ABF1 PF04684.8 CDJ65086.1 - 0.00041 19.3 10.2 0.00041 19.3 7.1 17.4 11 5 5 18 18 18 1 BAF1 / ABF1 chromatin reorganising factor Dehydrin PF00257.14 CDJ65086.1 - 0.34 11.2 0.0 0.34 11.2 0.0 12.6 8 4 0 9 9 9 0 Dehydrin INCENP_ARK-bind PF03941.10 CDJ65087.1 - 0.0086 15.8 0.0 0.0086 15.8 0.0 3.1 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Mito_carr PF00153.22 CDJ65088.1 - 1.8e-56 187.8 7.1 3.8e-21 74.5 0.0 5.7 5 1 0 5 5 5 4 Mitochondrial carrier protein Mre11_DNA_bind PF04152.9 CDJ65089.1 - 1.9e-26 92.9 0.6 1.2e-19 70.8 0.0 3.8 3 1 1 4 4 4 2 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CDJ65089.1 - 7e-22 77.8 0.0 1.6e-21 76.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDJ65089.1 - 5e-08 32.9 0.1 0.0046 16.8 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain SlyX PF04102.7 CDJ65090.1 - 0.0074 16.6 9.6 0.2 12.0 0.0 3.6 3 0 0 3 3 3 2 SlyX DUF4463 PF14703.1 CDJ65090.1 - 0.22 12.0 1.9 2 9.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) Fib_alpha PF08702.5 CDJ65090.1 - 0.57 10.2 13.5 3.5 7.7 0.0 3.7 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 CDJ65090.1 - 1.2 9.5 12.2 1.4 9.3 0.3 3.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal WD40 PF00400.27 CDJ65091.1 - 0.0047 16.7 5.3 8.5 6.4 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat RNA_pol_Rpb4 PF03874.11 CDJ65092.1 - 5.7e-06 26.3 0.2 2.4e-05 24.2 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb4 DER1 PF04511.10 CDJ65093.1 - 1.3e-41 142.2 14.9 1.5e-41 142.1 10.3 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 CDJ65093.1 - 1.7e-05 24.8 16.5 3e-05 24.0 11.4 1.4 1 0 0 1 1 1 1 Rhomboid family FANCAA PF15146.1 CDJ65093.1 - 0.19 10.6 0.2 0.23 10.3 0.2 1.2 1 0 0 1 1 1 0 Fanconi anemia-associated zf-B_box PF00643.19 CDJ65094.1 - 9.7e-11 41.3 15.4 3e-05 23.8 4.7 2.3 2 0 0 2 2 2 2 B-box zinc finger Cript PF10235.4 CDJ65094.1 - 0.00076 19.7 4.1 0.00087 19.5 1.9 1.7 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT PARP PF00644.15 CDJ65094.1 - 0.005 16.2 0.5 0.022 14.1 0.3 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Leu_Phe_trans PF03588.9 CDJ65095.1 - 3.6e-16 58.7 0.1 5.7e-13 48.3 0.0 2.8 3 0 0 3 3 3 2 Leucyl/phenylalanyl-tRNA protein transferase 3A PF00803.13 CDJ65098.1 - 0.15 11.1 1.5 0.25 10.3 0.1 1.9 2 0 0 2 2 2 0 3A/RNA2 movement protein family Utp11 PF03998.8 CDJ65100.1 - 3.6e-18 66.2 41.8 1.9e-17 63.9 2.1 3.1 2 1 0 2 2 2 2 Utp11 protein SPX PF03105.14 CDJ65102.1 - 0.023 14.4 0.2 0.023 14.4 0.1 2.5 2 1 0 2 2 2 0 SPX domain Kinesin PF00225.18 CDJ65103.1 - 7.1e-92 307.6 1.5 7.1e-92 307.6 1.1 6.0 5 2 0 5 5 5 1 Kinesin motor domain CAF-1_p150 PF11600.3 CDJ65103.1 - 0.00024 20.5 42.3 0.00024 20.5 29.3 17.3 13 6 3 16 16 16 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF755 PF05501.6 CDJ65103.1 - 0.00065 19.7 3.3 0.00065 19.7 2.3 24.3 23 2 3 26 26 26 2 Domain of unknown function (DUF755) FimP PF09766.4 CDJ65103.1 - 0.00095 18.3 5.1 0.00095 18.3 3.6 12.0 10 3 2 12 12 12 3 Fms-interacting protein Spore_coat_CotO PF14153.1 CDJ65103.1 - 0.0028 17.1 5.0 0.0028 17.1 3.4 11.1 10 2 1 11 11 11 1 Spore coat protein CotO GAGA_bind PF06217.7 CDJ65105.1 - 2.4 8.0 26.4 5.1 6.9 18.3 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family Proteasome PF00227.21 CDJ65106.1 - 9.5e-30 103.2 0.0 1.5e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDJ65106.1 - 3.8e-12 45.2 0.1 8.5e-12 44.1 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RskA PF10099.4 CDJ65106.1 - 1.9 8.2 7.8 5 6.8 5.5 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Gln-synt_C PF00120.19 CDJ65108.1 - 5.3e-58 196.2 7.0 2.1e-29 102.4 1.5 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Peptidase_M20 PF01546.23 CDJ65108.1 - 0.084 12.3 1.1 0.13 11.7 0.7 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Rifin_STEVOR PF02009.11 CDJ65108.1 - 0.89 9.1 5.9 1.1 8.7 4.1 1.1 1 0 0 1 1 1 0 Rifin/stevor family Med15 PF09606.5 CDJ65108.1 - 1.8 6.6 11.0 2.4 6.2 7.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TT_ORF2 PF02957.10 CDJ65108.1 - 9.2 6.9 10.4 19 5.9 7.2 1.5 1 0 0 1 1 1 0 TT viral ORF2 DUF755 PF05501.6 CDJ65109.1 - 0.0072 16.3 24.8 0.0072 16.3 17.2 9.8 8 2 1 9 9 9 1 Domain of unknown function (DUF755) UFD1 PF03152.9 CDJ65110.1 - 7.1e-67 223.9 0.0 1.1e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 IncA PF04156.9 CDJ65110.1 - 0.00017 21.2 13.4 0.00017 21.2 9.3 5.5 5 1 1 6 6 4 1 IncA protein WD40 PF00400.27 CDJ65110.1 - 0.0011 18.8 2.2 0.0027 17.5 1.6 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat Ribosomal_60s PF00428.14 CDJ65110.1 - 0.0088 16.4 12.0 0.0088 16.4 8.3 10.9 6 1 0 6 6 5 2 60s Acidic ribosomal protein AAA_23 PF13476.1 CDJ65110.1 - 0.037 14.3 11.2 0.034 14.4 4.8 2.2 2 0 0 2 2 2 0 AAA domain FimP PF09766.4 CDJ65110.1 - 0.066 12.2 20.5 0.021 13.9 10.4 2.1 2 0 0 2 2 2 0 Fms-interacting protein Ycf1 PF05758.7 CDJ65110.1 - 0.25 9.0 5.5 0.33 8.5 3.8 1.1 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDJ65110.1 - 0.31 9.6 10.5 0.59 8.6 7.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FA_desaturase PF00487.19 CDJ65110.1 - 1.3 8.4 6.1 3.5 6.9 4.0 1.9 1 1 0 1 1 1 0 Fatty acid desaturase Serinc PF03348.10 CDJ65110.1 - 2.1 6.9 8.3 5.6 5.5 5.7 1.6 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex16 PF08610.5 CDJ65110.1 - 2.8 6.8 9.4 0.31 9.9 3.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) SID-1_RNA_chan PF13965.1 CDJ65110.1 - 2.9 5.9 3.4 4.6 5.2 2.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EIIBC-GUT_N PF03612.9 CDJ65110.1 - 5.7 6.5 8.3 23 4.5 5.8 2.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF106 PF01956.11 CDJ65110.1 - 5.7 6.4 5.7 13 5.2 4.0 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 OATP PF03137.15 CDJ65110.1 - 6.6 4.6 7.3 13 3.6 5.1 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GFA PF04828.9 CDJ65111.1 - 9.6 6.2 7.9 0.9 9.5 0.9 2.7 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF3273 PF11677.3 CDJ65112.1 - 9.4e-11 41.4 0.2 1.4e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) RRM_1 PF00076.17 CDJ65114.1 - 4.7e-32 109.4 0.2 6.5e-15 54.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ65114.1 - 8.1e-27 93.0 0.0 1.9e-12 46.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ65114.1 - 1.4e-10 40.8 0.0 0.00072 19.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CDJ65114.1 - 0.0079 15.6 0.2 0.17 11.4 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain TPR_11 PF13414.1 CDJ65115.1 - 6.4e-11 41.7 9.3 5.9e-10 38.6 2.7 4.8 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 CDJ65115.1 - 1.3e-09 37.1 12.2 7.4e-05 22.3 0.5 5.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ65115.1 - 5.3e-07 28.9 5.1 0.0053 16.3 0.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ65115.1 - 3.4e-05 23.2 1.5 0.021 14.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ65115.1 - 0.0002 21.9 7.1 0.0002 21.9 5.0 8.2 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ65115.1 - 0.0038 17.0 8.5 0.014 15.2 2.9 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ65115.1 - 0.0057 17.0 0.7 0.0057 17.0 0.5 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat Het-C PF07217.6 CDJ65115.1 - 0.043 12.0 0.1 0.082 11.0 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Fis1_TPR_C PF14853.1 CDJ65115.1 - 0.075 12.9 7.1 0.043 13.7 0.4 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 CDJ65115.1 - 0.23 11.7 9.3 0.17 12.1 0.3 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3361 PF11841.3 CDJ65115.1 - 4.7 6.9 6.6 11 5.7 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Nop PF01798.13 CDJ65116.1 - 3.1e-51 172.6 3.0 1.3e-50 170.5 1.9 2.1 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CDJ65116.1 - 5e-28 96.6 0.1 9.5e-28 95.7 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CDJ65116.1 - 3.3e-16 59.1 0.9 7.5e-16 58.0 0.6 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF3138 PF11336.3 CDJ65116.1 - 0.11 10.5 0.9 0.18 9.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PIP5K PF01504.13 CDJ65117.1 - 1.6e-35 122.4 0.0 1.4e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.16 CDJ65117.1 - 2.5e-14 52.8 10.9 2.5e-14 52.8 7.6 2.9 3 0 0 3 3 3 1 FYVE zinc finger Cpn60_TCP1 PF00118.19 CDJ65117.1 - 0.083 11.4 0.0 0.24 10.0 0.0 1.7 2 0 0 2 2 2 0 TCP-1/cpn60 chaperonin family DUF814 PF05670.8 CDJ65118.1 - 9.5e-17 60.6 0.1 3.6e-12 45.9 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF814) TrbC PF04956.8 CDJ65118.1 - 2.2 8.3 0.0 2.2 8.3 0.0 3.4 3 1 0 3 3 3 0 TrbC/VIRB2 family DNA_topoisoIV PF00521.15 CDJ65119.1 - 1.6e-83 280.9 0.1 1.3e-77 261.5 0.0 2.3 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.8 CDJ65119.1 - 1.8e-24 84.7 6.3 9.1e-08 31.2 0.0 5.1 6 0 0 6 6 6 4 DNA gyrase C-terminal domain, beta-propeller PNTB PF02233.11 CDJ65120.1 - 1.4e-24 86.7 0.0 2.3e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 CDJ65120.1 - 9.6e-11 41.5 4.1 1.2e-09 37.9 0.1 2.9 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 CDJ65120.1 - 0.0018 18.3 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain NAD_binding_7 PF13241.1 CDJ65120.1 - 0.087 13.0 0.3 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 CDJ65120.1 - 0.16 12.4 0.5 0.35 11.2 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CDJ65120.1 - 1.2 8.1 7.8 0.074 12.1 1.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase CASP_C PF08172.7 CDJ65121.1 - 8.8e-09 34.7 0.1 8.8e-09 34.7 0.1 5.8 2 1 4 6 6 6 2 CASP C terminal DUF2730 PF10805.3 CDJ65121.1 - 0.018 14.7 1.6 0.018 14.7 1.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) PHD PF00628.24 CDJ65122.1 - 6.3e-14 51.3 25.6 1.7e-11 43.5 9.2 4.4 2 1 2 4 4 4 2 PHD-finger C1_1 PF00130.17 CDJ65122.1 - 3.2e-05 23.5 33.1 0.00085 18.9 3.5 4.5 3 2 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 CDJ65122.1 - 5e-05 22.5 11.0 0.00046 19.4 0.5 5.3 6 1 0 6 6 6 2 PHD-finger zf-PHD-like PF15446.1 CDJ65122.1 - 0.051 12.8 22.2 0.1 11.9 1.0 2.9 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Trm112p PF03966.11 CDJ65122.1 - 0.78 10.1 4.7 0.29 11.5 0.6 2.3 2 1 0 2 2 2 0 Trm112p-like protein zf-RING_2 PF13639.1 CDJ65122.1 - 1.6 8.6 32.5 1.5 8.7 7.4 4.6 3 1 1 4 4 4 0 Ring finger domain Ecl1 PF12855.2 CDJ65123.1 - 0.052 12.8 0.3 0.15 11.3 0.2 1.7 1 0 0 1 1 1 0 Life-span regulatory factor PHD PF00628.24 CDJ65123.1 - 0.095 12.4 11.9 0.24 11.1 0.9 2.5 2 0 0 2 2 2 0 PHD-finger DUF1181 PF06680.6 CDJ65125.1 - 0.049 13.2 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1181) Dabb PF07876.7 CDJ65126.1 - 1.6e-18 66.9 0.3 1.9e-18 66.7 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Lactamase_B_2 PF12706.2 CDJ65127.1 - 2e-24 86.2 0.7 3.6e-23 82.1 0.5 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CDJ65127.1 - 3.3e-08 33.4 0.0 1.7e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDJ65127.1 - 2.2e-05 24.1 0.8 0.0024 17.5 0.2 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PI3_PI4_kinase PF00454.22 CDJ65128.1 - 2.5e-30 105.7 0.1 1e-29 103.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CDJ65128.1 - 2.5e-15 56.1 0.1 7.4e-09 35.0 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) P12 PF12669.2 CDJ65129.1 - 0.13 12.5 7.4 6.5 7.0 0.0 3.3 2 1 1 3 3 3 0 Virus attachment protein p12 family Cyto_ox_2 PF02322.10 CDJ65129.1 - 0.49 9.5 2.4 0.54 9.3 1.6 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II SR-25 PF10500.4 CDJ65129.1 - 2.7 7.3 19.2 13 5.1 13.3 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein TauE PF01925.14 CDJ65129.1 - 2.9 7.2 6.6 3.8 6.9 4.5 1.3 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Pneumo_att_G PF05539.6 CDJ65129.1 - 6.1 6.1 11.1 7 5.9 7.7 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Polysacc_synt_3 PF13440.1 CDJ65129.1 - 8 5.8 12.4 7.3 5.9 6.7 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein GTP_EFTU PF00009.22 CDJ65130.1 - 3.3e-07 29.9 0.0 5.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Sporozoite_P67 PF05642.6 CDJ65130.1 - 0.32 8.8 12.1 0.4 8.4 8.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 CDJ65130.1 - 0.65 8.2 20.5 0.91 7.7 14.2 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF515 PF04415.7 CDJ65130.1 - 1 7.5 19.7 1.7 6.8 13.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Drf_FH1 PF06346.7 CDJ65131.1 - 0.064 12.7 6.1 0.08 12.4 4.2 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 PROL5-SMR PF15621.1 CDJ65131.1 - 1.4 9.3 4.0 2.4 8.6 2.5 1.6 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family EFG_C PF00679.19 CDJ65132.1 - 3.6e-17 62.0 0.3 1.3e-15 57.0 0.2 2.2 1 1 0 1 1 1 1 Elongation factor G C-terminus Spt20 PF12090.3 CDJ65132.1 - 0.00051 19.4 0.7 0.0006 19.2 0.5 1.2 1 0 0 1 1 1 1 Spt20 family Prog_receptor PF02161.10 CDJ65132.1 - 0.0012 17.7 1.0 0.0016 17.3 0.2 1.5 2 0 0 2 2 2 1 Progesterone receptor Med15 PF09606.5 CDJ65132.1 - 0.0012 17.1 15.0 0.0013 17.0 10.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 CDJ65132.1 - 0.0025 17.7 3.8 0.0033 17.2 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Suf PF05843.9 CDJ65132.1 - 0.0086 15.8 4.7 0.011 15.4 3.2 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF3371 PF11851.3 CDJ65132.1 - 0.012 16.2 9.3 0.025 15.2 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) tRNA_synt_1c_R2 PF04557.10 CDJ65132.1 - 0.017 15.8 0.4 0.032 14.9 0.2 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 FimP PF09766.4 CDJ65132.1 - 0.029 13.4 8.8 0.04 12.9 6.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein DcuA_DcuB PF03605.9 CDJ65132.1 - 0.096 11.5 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4175 PF13779.1 CDJ65132.1 - 0.15 9.7 17.3 0.21 9.2 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Serinc PF03348.10 CDJ65132.1 - 0.17 10.5 0.5 0.2 10.3 0.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.10 CDJ65132.1 - 0.19 11.7 0.2 0.3 11.1 0.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Phosducin PF02114.11 CDJ65132.1 - 0.19 10.4 4.0 0.32 9.7 2.8 1.3 1 0 0 1 1 1 0 Phosducin Pex16 PF08610.5 CDJ65132.1 - 0.25 10.2 3.2 0.36 9.7 2.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TMEM51 PF15345.1 CDJ65132.1 - 0.44 10.1 5.9 0.65 9.6 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 BAF1_ABF1 PF04684.8 CDJ65132.1 - 0.94 8.2 17.1 1.2 7.8 11.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SHR3_chaperone PF08229.6 CDJ65132.1 - 1.3 7.9 4.3 2 7.3 2.9 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 NICE-3 PF07406.6 CDJ65133.1 - 0.014 14.8 0.5 0.025 14.0 0.3 1.4 1 1 0 1 1 1 0 NICE-3 protein ARGLU PF15346.1 CDJ65133.1 - 0.6 9.8 7.5 0.36 10.6 1.7 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 SR-25 PF10500.4 CDJ65135.1 - 0.00067 19.2 14.5 0.00081 18.9 10.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Herpes_UL69 PF05459.7 CDJ65135.1 - 0.43 9.6 6.9 1 8.4 3.4 2.0 2 0 0 2 2 2 0 Herpesvirus transcriptional regulator family BTG PF07742.7 CDJ65135.1 - 0.77 9.2 5.6 1.5 8.3 3.9 1.4 1 0 0 1 1 1 0 BTG family Herpes_LMP2 PF07415.6 CDJ65135.1 - 5.4 5.4 5.7 6 5.3 3.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF755 PF05501.6 CDJ65136.1 - 1.4 8.9 5.2 2.1 8.4 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TPPII_N PF12583.3 CDJ65136.1 - 3.6 7.7 10.2 4.1 7.5 7.1 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal CDK2AP PF09806.4 CDJ65136.1 - 7.4 6.7 12.4 8.7 6.5 8.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4349 PF14257.1 CDJ65136.1 - 8.4 5.5 9.4 9 5.4 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Dehydrin PF00257.14 CDJ65137.1 - 0.0026 18.0 12.9 0.23 11.7 2.3 4.2 4 0 0 4 4 4 2 Dehydrin DUF2352 PF09817.4 CDJ65137.1 - 0.016 13.4 5.4 0.026 12.6 3.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2352) HEAT_EZ PF13513.1 CDJ65138.1 - 1.5e-09 38.0 13.4 1.2e-07 31.9 1.7 17.4 10 7 9 19 19 19 7 HEAT-like repeat HEAT_2 PF13646.1 CDJ65138.1 - 3.2e-09 36.9 5.1 3.2e-09 36.9 3.5 11.6 5 4 6 12 12 12 6 HEAT repeats HEAT PF02985.17 CDJ65138.1 - 1.6e-05 24.6 0.1 1.6e-05 24.6 0.1 13.8 15 1 0 15 15 15 3 HEAT repeat CLASP_N PF12348.3 CDJ65138.1 - 0.00035 19.9 12.4 0.0055 16.0 1.9 5.3 4 3 1 5 5 5 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 CDJ65138.1 - 0.016 15.6 0.3 8 6.9 0.0 4.7 4 1 2 6 6 6 0 Vacuolar 14 Fab1-binding region DDHD PF02862.12 CDJ65138.1 - 0.54 10.0 14.5 0.43 10.3 3.8 2.4 2 0 0 2 2 2 0 DDHD domain SPX PF03105.14 CDJ65138.1 - 4.1 7.0 11.6 0.57 9.9 1.7 2.3 2 0 0 2 2 2 0 SPX domain Ribosomal_S26e PF01283.14 CDJ65139.1 - 1.4e-49 167.0 9.6 1.7e-49 166.8 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.12 CDJ65139.1 - 0.1 13.1 0.3 0.16 12.5 0.2 1.4 1 1 0 1 1 1 0 SRP19 protein Fer4_10 PF13237.1 CDJ65139.1 - 0.15 11.9 4.7 0.29 10.9 3.2 1.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain zf-ISL3 PF14690.1 CDJ65139.1 - 1 9.4 8.0 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.1 CDJ65139.1 - 3.5 6.9 6.1 0.16 11.2 0.4 1.7 2 0 0 2 2 2 0 zinc-ribbon domain JAB PF01398.16 CDJ65140.1 - 5.6e-26 90.5 0.0 1.7e-25 88.9 0.0 1.8 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CDJ65140.1 - 7.4e-08 31.9 0.1 1.2e-06 28.0 0.1 2.4 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CDJ65140.1 - 0.019 14.4 0.1 0.052 13.0 0.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) zf-CCHC PF00098.18 CDJ65142.1 - 9.6e-08 31.6 11.0 5.1e-06 26.1 1.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ65142.1 - 0.0026 17.4 0.4 0.0026 17.4 0.3 2.3 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ65142.1 - 0.0081 15.8 1.1 0.0081 15.8 0.8 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ65142.1 - 0.029 14.0 7.5 0.048 13.3 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ65142.1 - 0.034 14.1 6.9 0.074 13.1 4.8 1.5 1 0 0 1 1 1 0 DnaJ central domain Retrotrans_gag PF03732.12 CDJ65142.1 - 0.11 12.5 0.1 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_2 PF13696.1 CDJ65142.1 - 0.42 10.1 5.4 0.16 11.4 0.7 2.3 1 1 1 2 2 2 0 Zinc knuckle DUF3552 PF12072.3 CDJ65143.1 - 0.062 12.5 0.5 0.09 11.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Aminotran_1_2 PF00155.16 CDJ65144.1 - 5.8e-43 147.2 0.0 1.6e-41 142.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CDJ65144.1 - 0.00064 18.1 0.0 0.0011 17.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CDJ65144.1 - 0.00081 18.5 1.0 0.00081 18.5 0.7 2.6 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CDJ65144.1 - 0.0038 16.4 0.0 0.016 14.3 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 CDJ65144.1 - 0.017 13.7 0.0 0.034 12.6 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain T2SF PF00482.18 CDJ65144.1 - 0.25 11.2 2.1 0.37 10.7 0.4 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F MFS_1 PF07690.11 CDJ65145.1 - 4.8e-10 38.6 28.9 4.8e-10 38.6 20.0 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily ERGIC_N PF13850.1 CDJ65145.1 - 0.067 13.1 0.3 0.29 11.1 0.2 2.1 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MMR_HSR1 PF01926.18 CDJ65146.1 - 2.1e-16 59.9 0.0 1.6e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase NGP1NT PF08153.7 CDJ65146.1 - 8.5e-06 25.7 0.0 4e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain DUF258 PF03193.11 CDJ65146.1 - 0.00077 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CDJ65146.1 - 0.0011 18.3 0.1 0.0034 16.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 CDJ65146.1 - 0.019 14.1 0.0 0.92 8.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF3388 PF11868.3 CDJ65146.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) Dynamin_N PF00350.18 CDJ65146.1 - 0.055 13.2 0.1 3 7.6 0.0 2.9 2 1 1 3 3 3 0 Dynamin family Ribosomal_60s PF00428.14 CDJ65147.1 - 0.004 17.5 7.9 0.0057 17.0 5.5 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein CP12 PF02672.10 CDJ65147.1 - 0.086 13.3 0.7 0.086 13.3 0.5 1.7 1 1 1 2 2 2 0 CP12 domain MCLC PF05934.6 CDJ65147.1 - 0.23 9.7 1.4 0.24 9.6 1.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF3123 PF11321.3 CDJ65147.1 - 9.8 6.5 8.1 12 6.2 5.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) Ribosomal_60s PF00428.14 CDJ65148.1 - 0.012 15.9 2.6 0.05 14.0 1.8 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein FHIPEP PF00771.15 CDJ65148.1 - 0.029 12.7 0.1 0.029 12.7 0.1 3.0 2 1 0 2 2 2 0 FHIPEP family CobD_Cbib PF03186.8 CDJ65151.1 - 0.021 13.8 0.5 0.022 13.8 0.4 1.1 1 0 0 1 1 1 0 CobD/Cbib protein Ribosomal_60s PF00428.14 CDJ65151.1 - 0.048 14.0 0.2 0.048 14.0 0.2 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3602 PF12223.3 CDJ65151.1 - 0.1 13.0 4.1 0.12 12.8 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) Endonuc_Holl PF10107.4 CDJ65151.1 - 0.59 9.8 9.7 0.68 9.6 6.7 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Bap31 PF05529.7 CDJ65151.1 - 1.1 8.7 6.4 1.3 8.4 4.4 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4407 PF14362.1 CDJ65151.1 - 1.2 7.9 15.5 1.4 7.8 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1675 PF07897.6 CDJ65151.1 - 2 8.2 7.4 2.1 8.1 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Presenilin PF01080.12 CDJ65151.1 - 2.2 6.9 5.4 2.4 6.8 3.7 1.0 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.1 CDJ65152.1 - 0.09 12.2 0.4 0.13 11.6 0.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO ATG16 PF08614.6 CDJ65152.1 - 1.6 8.4 5.4 1.8 8.3 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FGF-BP1 PF06473.7 CDJ65152.1 - 2.9 7.4 6.6 4.5 6.7 4.6 1.3 1 1 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) UQ_con PF00179.21 CDJ65153.1 - 1.2e-08 34.4 0.8 1.2e-08 34.4 0.5 3.6 2 2 2 4 4 4 1 Ubiquitin-conjugating enzyme DUF1180 PF06679.7 CDJ65153.1 - 4.4 7.1 6.3 2.5 7.9 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Dpy-30 PF05186.8 CDJ65160.1 - 1e-12 47.3 0.1 1.7e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif PsbI PF02532.9 CDJ65161.1 - 0.0069 15.9 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) zf-H2C2_2 PF13465.1 CDJ65161.1 - 0.057 13.7 1.3 0.17 12.2 0.9 1.9 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 CDJ65161.1 - 0.83 9.3 7.3 0.5 10.1 3.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RVT_1 PF00078.22 CDJ65162.1 - 8.1e-17 61.2 0.0 4.6e-16 58.8 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CDJ65162.1 - 2e-05 24.8 0.0 8.1e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GSH-S_ATP PF02955.11 CDJ65162.1 - 0.024 13.7 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Nop14 PF04147.7 CDJ65165.1 - 0.0014 16.6 19.3 0.0015 16.5 13.3 1.0 1 0 0 1 1 1 1 Nop14-like family DDHD PF02862.12 CDJ65165.1 - 0.027 14.2 5.1 0.031 14.0 3.6 1.1 1 0 0 1 1 1 0 DDHD domain NOA36 PF06524.7 CDJ65165.1 - 0.066 12.4 12.9 0.087 12.0 8.9 1.1 1 0 0 1 1 1 0 NOA36 protein Rhabdo_ncap PF00945.13 CDJ65165.1 - 0.07 11.7 6.5 0.083 11.4 4.5 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein BUD22 PF09073.5 CDJ65165.1 - 0.14 11.1 19.7 0.17 10.9 13.7 1.1 1 0 0 1 1 1 0 BUD22 Spore_coat_CotO PF14153.1 CDJ65165.1 - 0.16 11.3 18.9 0.2 11.0 13.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 CDJ65165.1 - 0.22 10.8 20.7 0.28 10.5 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pilt PF15453.1 CDJ65165.1 - 0.23 11.0 8.4 0.24 11.0 5.8 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions RR_TM4-6 PF06459.7 CDJ65165.1 - 0.27 11.0 12.3 0.3 10.9 8.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CDJ65165.1 - 0.28 10.1 5.4 0.31 10.0 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CDJ65165.1 - 0.53 8.2 20.0 0.63 8.0 13.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CDJ65165.1 - 0.53 8.6 27.1 0.65 8.4 18.8 1.0 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 CDJ65165.1 - 0.64 7.6 10.0 0.7 7.5 6.9 1.0 1 0 0 1 1 1 0 Ycf1 CENP-T PF15511.1 CDJ65165.1 - 0.77 8.9 15.7 0.92 8.6 10.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TRAP_alpha PF03896.11 CDJ65165.1 - 0.84 8.5 14.9 1 8.2 10.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 CDJ65165.1 - 0.87 9.1 17.7 1.2 8.6 12.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region MIP-T3 PF10243.4 CDJ65165.1 - 0.89 7.9 21.3 1 7.7 14.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNA_pol_3_Rpc31 PF11705.3 CDJ65165.1 - 0.95 9.3 23.2 1.4 8.7 16.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Merozoite_SPAM PF07133.6 CDJ65165.1 - 1 9.2 32.4 1.3 8.9 22.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) FLO_LFY PF01698.11 CDJ65165.1 - 1.3 7.8 9.3 1.4 7.6 6.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 CDJ65165.1 - 1.5 7.2 8.0 1.8 6.9 5.5 1.0 1 0 0 1 1 1 0 Raftlin CobT PF06213.7 CDJ65165.1 - 1.6 7.7 23.5 2 7.4 16.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.9 CDJ65165.1 - 1.7 8.1 16.1 2.3 7.7 11.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.7 CDJ65165.1 - 1.8 7.7 22.9 2.2 7.5 15.8 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.8 CDJ65165.1 - 2 7.0 25.7 2.3 6.8 17.8 1.1 1 0 0 1 1 1 0 Paf1 Usp PF00582.21 CDJ65165.1 - 2 8.6 8.0 2.8 8.1 5.5 1.4 1 0 0 1 1 1 0 Universal stress protein family VID27 PF08553.5 CDJ65165.1 - 2 6.5 19.4 2.3 6.3 13.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 CDJ65165.1 - 2.7 6.5 23.9 3.5 6.2 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Plasmodium_Vir PF05795.6 CDJ65165.1 - 2.7 7.0 5.6 3.1 6.9 3.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PPP4R2 PF09184.6 CDJ65165.1 - 2.9 7.3 24.2 3.6 7.0 16.8 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2201_N PF13203.1 CDJ65165.1 - 3 6.9 12.0 3.3 6.8 8.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2413 PF10310.4 CDJ65165.1 - 3.8 6.2 15.6 4.5 5.9 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SpoIIP PF07454.6 CDJ65165.1 - 3.8 6.6 10.6 4.5 6.3 7.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.2 CDJ65165.1 - 4 4.9 4.5 4.1 4.9 3.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DARPP-32 PF05395.7 CDJ65165.1 - 4.7 7.3 18.6 7.3 6.7 12.9 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 CDC27 PF09507.5 CDJ65165.1 - 5.9 5.9 19.9 7.4 5.6 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 U79_P34 PF03064.11 CDJ65165.1 - 8.8 5.7 13.5 11 5.5 9.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Sec62 PF03839.11 CDJ65165.1 - 9.3 5.5 9.9 12 5.2 6.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 zf-CCHC PF00098.18 CDJ65167.1 - 1.4e-10 40.5 8.8 8.4e-05 22.3 0.5 2.6 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ65167.1 - 0.0023 17.9 4.4 0.0023 17.9 3.0 1.7 2 0 0 2 2 2 1 DnaJ central domain zf-CCHC_2 PF13696.1 CDJ65167.1 - 0.0043 16.5 8.9 0.082 12.4 0.0 2.8 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_5 PF14787.1 CDJ65167.1 - 0.022 14.2 1.3 0.022 14.2 0.9 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 CDJ65167.1 - 0.023 14.3 3.0 1.1 9.0 0.1 2.4 1 1 1 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.12 CDJ65167.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.7 1 1 1 2 2 2 0 Retrotransposon gag protein zf-CCHC_4 PF14392.1 CDJ65167.1 - 0.21 11.2 6.9 2.2 8.0 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 CDJ65167.1 - 0.59 10.0 6.9 8.1 6.3 0.8 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G IQ-like PF15157.1 CDJ65168.1 - 0.022 14.9 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 IQ-like FAM196 PF15265.1 CDJ65169.1 - 4.2 6.4 26.6 5 6.2 18.4 1.0 1 0 0 1 1 1 0 FAM196 family Spt20 PF12090.3 CDJ65170.1 - 0.099 11.9 7.3 0.41 9.9 3.5 2.1 2 0 0 2 2 2 0 Spt20 family DUF1669 PF07894.7 CDJ65170.1 - 0.37 9.9 3.5 0.53 9.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) DUF4557 PF15101.1 CDJ65170.1 - 0.63 9.8 13.0 4.9 6.9 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) RAB3GAP2_N PF14655.1 CDJ65170.1 - 0.64 8.9 11.1 0.13 11.2 4.3 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PHD_3 PF13922.1 CDJ65170.1 - 4.5 7.5 11.9 2.2 8.5 4.0 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx APC_CDC26 PF10471.4 CDJ65170.1 - 8.2 7.2 26.4 1.1 10.0 8.7 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 SR-25 PF10500.4 CDJ65171.1 - 0.00019 20.9 1.2 0.00028 20.4 0.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.4 CDJ65171.1 - 0.052 13.2 6.2 0.083 12.6 4.3 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SASRP1 PF15160.1 CDJ65171.1 - 0.07 12.3 0.3 0.092 11.9 0.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 TPR_11 PF13414.1 CDJ65172.1 - 4.1e-09 35.9 21.5 6.8e-05 22.4 4.3 3.5 3 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 CDJ65172.1 - 6.8e-08 31.8 18.7 0.00029 20.3 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ65172.1 - 3.4e-07 29.6 17.0 0.014 15.3 1.8 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ65172.1 - 0.001 18.6 14.3 0.085 12.6 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat SR-25 PF10500.4 CDJ65172.1 - 1.5 8.2 23.7 0.034 13.5 2.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_8 PF13181.1 CDJ65172.1 - 5.3 7.0 12.6 35 4.4 0.5 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Transposase_22 PF02994.9 CDJ65173.1 - 0.00032 19.3 1.1 0.00032 19.3 0.7 2.9 2 1 0 2 2 2 1 L1 transposable element Lebercilin PF15619.1 CDJ65173.1 - 0.006 16.0 25.8 0.006 16.0 17.9 3.7 3 1 1 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease Ribosomal_60s PF00428.14 CDJ65173.1 - 0.012 16.0 2.7 0.012 16.0 1.9 4.7 3 1 1 4 4 4 0 60s Acidic ribosomal protein Reo_sigmaC PF04582.7 CDJ65173.1 - 0.91 8.6 4.9 0.99 8.5 0.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Viral_cys_rich PF08008.7 CDJ65173.1 - 3.4 7.2 10.5 3 7.4 0.3 2.6 1 1 1 2 2 2 0 Viral cysteine rich Peptidase_M24 PF00557.19 CDJ65174.1 - 0.0097 15.5 0.0 0.0097 15.5 0.0 2.7 2 1 1 3 3 3 1 Metallopeptidase family M24 Med15 PF09606.5 CDJ65174.1 - 0.12 10.6 29.6 0.14 10.3 20.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ65175.1 - 0.11 12.9 3.1 0.17 12.2 2.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ65176.1 - 0.0015 18.0 6.0 0.002 17.6 4.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.6 CDJ65176.1 - 0.019 12.8 2.7 0.023 12.5 1.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LPP20 PF02169.11 CDJ65176.1 - 0.081 13.0 5.9 0.14 12.2 4.1 1.4 1 0 0 1 1 1 0 LPP20 lipoprotein APC_CDC26 PF10471.4 CDJ65176.1 - 0.16 12.7 5.0 0.75 10.5 3.9 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF775 PF05603.7 CDJ65176.1 - 0.25 10.8 3.4 0.3 10.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Transposase_24 PF03004.9 CDJ65176.1 - 0.39 10.6 3.8 0.65 9.8 2.6 1.3 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Kei1 PF08552.6 CDJ65176.1 - 0.56 9.8 3.2 0.74 9.4 2.2 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TraG_N PF07916.6 CDJ65176.1 - 6.2 5.1 8.0 7.5 4.8 5.6 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region PCI PF01399.22 CDJ65177.1 - 2.1e-12 47.2 0.3 6.2e-12 45.7 0.2 1.8 1 1 0 1 1 1 1 PCI domain DUF1699 PF08004.6 CDJ65177.1 - 0.037 13.5 0.2 0.13 11.7 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1699) DUF3881 PF12997.2 CDJ65177.1 - 0.27 10.2 2.0 0.84 8.5 0.5 2.0 1 1 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) Peptidase_S8 PF00082.17 CDJ65178.1 - 9.8e-10 38.0 0.3 9.8e-10 38.0 0.2 2.1 2 0 0 2 2 2 1 Subtilase family Shadoo PF14999.1 CDJ65178.1 - 0.0089 15.8 5.8 0.019 14.8 4.1 1.5 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Tim54 PF11711.3 CDJ65178.1 - 0.028 13.0 5.6 0.034 12.7 3.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YjgP_YjgQ PF03739.9 CDJ65178.1 - 0.15 10.7 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Zip PF02535.17 CDJ65178.1 - 0.35 9.8 1.0 0.41 9.6 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MRP-S31 PF15433.1 CDJ65178.1 - 0.61 9.4 14.2 0.82 9.0 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 BAF1_ABF1 PF04684.8 CDJ65178.1 - 0.61 8.8 7.2 0.85 8.3 5.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1510 PF07423.6 CDJ65178.1 - 0.62 9.3 21.2 0.79 9.0 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3807 PF12720.2 CDJ65178.1 - 0.92 9.6 16.2 1.3 9.1 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Vfa1 PF08432.5 CDJ65178.1 - 1.5 8.8 23.1 2 8.4 16.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 CDJ65178.1 - 2.2 8.1 6.3 2.8 7.7 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MFMR PF07777.6 CDJ65178.1 - 3.1 7.6 8.1 4.1 7.2 5.6 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR U79_P34 PF03064.11 CDJ65178.1 - 4.5 6.7 14.1 5.9 6.3 9.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 CDJ65178.1 - 5.2 6.8 14.1 7.9 6.2 9.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDHD PF02862.12 CDJ65178.1 - 8 6.1 11.8 11 5.7 8.2 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_S8 PF00082.17 CDJ65179.1 - 6.6e-29 100.9 9.7 6.6e-29 100.9 6.7 3.2 2 1 0 2 2 2 1 Subtilase family Vps16_C PF04840.7 CDJ65180.1 - 7.4e-39 133.5 0.2 7.4e-39 133.5 0.2 2.3 2 1 0 2 2 2 1 Vps16, C-terminal region LCCL PF03815.14 CDJ65181.1 - 2.3e-09 37.1 0.1 2.3e-09 37.1 0.1 2.2 2 0 0 2 2 2 1 LCCL domain Rxt3 PF08642.5 CDJ65181.1 - 0.13 12.4 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF605 PF04652.11 CDJ65181.1 - 5.7 6.2 42.2 0.096 12.0 5.2 3.0 3 0 0 3 3 3 0 Vta1 like F-box PF00646.28 CDJ65182.1 - 0.0073 15.9 0.1 0.026 14.1 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CDJ65182.1 - 0.067 12.9 0.1 0.31 10.7 0.1 2.2 1 0 0 1 1 1 0 F-box-like DUF4118 PF13493.1 CDJ65184.1 - 0.36 11.0 5.1 0.59 10.3 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DDHD PF02862.12 CDJ65185.1 - 0.004 16.9 2.0 0.11 12.3 0.7 2.3 2 0 0 2 2 2 1 DDHD domain ANTH PF07651.11 CDJ65185.1 - 0.064 11.9 0.7 0.11 11.1 0.5 1.3 1 0 0 1 1 1 0 ANTH domain Corona_nucleoca PF00937.13 CDJ65185.1 - 0.16 10.8 9.5 0.3 9.9 6.6 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Suf PF05843.9 CDJ65185.1 - 0.21 11.2 7.4 0.049 13.3 2.7 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ65188.1 - 0.052 11.7 99.7 0.053 11.7 69.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ65188.1 - 9 4.3 88.3 12 3.9 61.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA-synt_1d PF00750.14 CDJ65189.1 - 2.6e-44 151.4 0.0 2.6e-44 151.4 0.0 2.9 2 1 0 2 2 2 1 tRNA synthetases class I (R) Ribosomal_60s PF00428.14 CDJ65189.1 - 0.025 14.9 2.2 0.025 14.9 1.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein D5_N PF08706.6 CDJ65189.1 - 0.064 13.3 0.1 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 D5 N terminal like DUF1980 PF09323.5 CDJ65189.1 - 0.42 10.3 3.7 0.59 9.8 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Shadoo PF14999.1 CDJ65189.1 - 0.83 9.5 11.7 2.5 7.9 1.8 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective OATP PF03137.15 CDJ65189.1 - 1.7 6.5 4.3 2.1 6.2 3.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_U57 PF05582.7 CDJ65189.1 - 2.3 7.1 9.3 4.1 6.2 6.4 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Gag_spuma PF03276.9 CDJ65189.1 - 3.1 6.0 27.0 4.3 5.5 18.7 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF4259 PF14078.1 CDJ65189.1 - 5.3 7.5 14.7 1.6 9.2 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) DUF775 PF05603.7 CDJ65189.1 - 6.5 6.2 16.1 0.45 10.0 7.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF775) LMBR1 PF04791.11 CDJ65190.1 - 0.62 8.5 4.1 2.4e+02 0.0 0.0 3.3 1 1 0 2 2 2 0 LMBR1-like membrane protein DUF2512 PF10710.4 CDJ65190.1 - 2.8 7.3 4.0 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) DUF3006 PF11213.3 CDJ65193.1 - 8.5e-06 25.4 0.0 1.8e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3006) Dynactin_p62 PF05502.8 CDJ65194.1 - 5.1e-20 71.6 17.6 4.6e-14 52.0 5.0 3.5 3 0 0 3 3 3 3 Dynactin p62 family Ribosomal_L18ae PF01775.12 CDJ65195.1 - 4.2e-38 130.0 0.0 5.1e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Spt20 PF12090.3 CDJ65196.1 - 0.083 12.2 15.8 0.11 11.7 0.6 2.3 2 0 0 2 2 2 0 Spt20 family DUF3801 PF12687.2 CDJ65196.1 - 1 8.8 11.3 3.3 7.2 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) FimP PF09766.4 CDJ65196.1 - 1.3 8.0 27.5 0.019 14.0 2.7 2.2 2 0 0 2 2 2 0 Fms-interacting protein Med15 PF09606.5 CDJ65196.1 - 4.3 5.4 52.3 0.0083 14.3 8.4 3.1 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 CDJ65197.1 - 6.6 6.7 5.5 9.2 6.3 3.8 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Yip1 PF04893.12 CDJ65198.1 - 4.7e-10 39.2 14.0 6.6e-10 38.7 9.7 1.3 1 0 0 1 1 1 1 Yip1 domain Ribosomal_60s PF00428.14 CDJ65198.1 - 0.045 14.1 2.9 0.046 14.1 0.8 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 CDJ65198.1 - 2 9.0 10.4 1.8 9.1 1.3 2.4 2 0 0 2 2 2 0 Chorion family 2 SR-25 PF10500.4 CDJ65198.1 - 9.3 5.6 11.0 13 5.1 7.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ65199.1 - 3.1 7.2 12.2 4.4 6.6 8.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SMC_N PF02463.14 CDJ65200.1 - 4.5e-10 39.1 0.0 9.3e-10 38.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Suf PF05843.9 CDJ65202.1 - 0.088 12.5 9.2 0.11 12.1 6.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ65202.1 - 0.093 12.0 2.4 0.12 11.6 1.7 1.2 1 0 0 1 1 1 0 Spt20 family CAF-1_p150 PF11600.3 CDJ65202.1 - 0.14 11.5 15.2 0.26 10.6 10.6 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 CDJ65202.1 - 0.24 11.2 4.6 0.37 10.6 3.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF605 PF04652.11 CDJ65202.1 - 0.68 9.2 19.4 0.88 8.8 13.5 1.1 1 0 0 1 1 1 0 Vta1 like RR_TM4-6 PF06459.7 CDJ65202.1 - 1.4 8.7 10.4 2.2 8.1 7.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AUX_IAA PF02309.11 CDJ65202.1 - 2.4 7.8 7.6 3.4 7.3 5.2 1.4 1 0 0 1 1 1 0 AUX/IAA family Hex_IIIa PF02455.11 CDJ65202.1 - 3.8 6.1 8.8 4.7 5.7 6.1 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PAT1 PF09770.4 CDJ65202.1 - 4.5 5.3 17.0 5.4 5.1 11.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_C1 PF00112.18 CDJ65205.1 - 6.1e-06 26.2 0.0 6.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Abi PF02517.11 CDJ65206.1 - 7.1e-09 35.6 0.0 3.3e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 CAAX protease self-immunity EcsB PF05975.7 CDJ65206.1 - 0.029 12.8 0.0 0.046 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB PrsW-protease PF13367.1 CDJ65206.1 - 0.13 11.4 2.2 1.1 8.4 0.1 2.4 2 0 0 2 2 2 0 Protease prsW family PT-VENN PF04829.8 CDJ65206.1 - 0.59 9.7 5.1 1.4 8.4 3.6 1.6 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Peptidase_M14 PF00246.19 CDJ65207.1 - 4.8e-13 49.3 0.0 6.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase MOZART2 PF12926.2 CDJ65207.1 - 0.0035 16.9 0.1 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 Mitotic-spindle organizing gamma-tubulin ring associated Arf PF00025.16 CDJ65208.1 - 2.3e-66 222.3 0.0 2.7e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CDJ65208.1 - 1.8e-11 43.3 1.1 1.1e-07 30.8 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CDJ65208.1 - 8e-10 38.3 0.0 9.9e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CDJ65208.1 - 1.3e-08 34.2 0.0 1.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CDJ65208.1 - 2.4e-07 31.2 0.0 3.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CDJ65208.1 - 1.2e-06 28.4 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CDJ65208.1 - 1.3e-05 24.4 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDJ65208.1 - 0.00013 21.4 0.0 0.0019 17.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CDJ65208.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CDJ65208.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1032 PF06278.6 CDJ65209.1 - 3.4e-08 32.4 2.3 0.00075 18.1 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1032) ScpA_ScpB PF02616.9 CDJ65209.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 ScpA/B protein Pyr_redox_2 PF07992.9 CDJ65211.1 - 5.9e-15 55.6 5.8 7.2e-10 39.0 0.0 3.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDJ65211.1 - 7.9e-13 48.6 0.0 2.6e-10 40.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDJ65211.1 - 0.0066 16.5 0.0 0.25 11.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EMI PF07546.8 CDJ65211.1 - 0.08 13.4 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 EMI domain NAD_binding_7 PF13241.1 CDJ65211.1 - 0.15 12.3 0.1 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 CDJ65211.1 - 0.17 11.9 0.0 0.17 11.9 0.0 3.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain UCH PF00443.24 CDJ65212.1 - 2.6e-44 151.3 0.0 1.8e-43 148.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDJ65212.1 - 1.2e-18 67.5 0.0 1.3e-09 37.9 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CDJ65212.1 - 0.00054 19.4 0.0 0.00097 18.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Ribosomal_60s PF00428.14 CDJ65212.1 - 0.012 15.9 0.3 0.012 15.9 0.2 9.5 7 2 1 9 9 9 0 60s Acidic ribosomal protein FliM PF02154.10 CDJ65212.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar motor switch protein FliM DUF308 PF03729.8 CDJ65213.1 - 0.0076 16.2 0.8 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) DUF3185 PF11381.3 CDJ65213.1 - 0.039 13.7 0.5 0.27 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3040 PF11239.3 CDJ65213.1 - 0.091 12.8 0.8 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) TctB PF07331.6 CDJ65213.1 - 0.22 11.1 3.1 2 8.0 0.4 2.7 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Epimerase PF01370.16 CDJ65214.1 - 1.6e-63 214.2 0.0 2e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDJ65214.1 - 3.4e-11 42.5 0.0 4.7e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CDJ65214.1 - 0.0033 16.3 0.0 0.0066 15.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CDJ65214.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 CDJ65214.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding His_Phos_2 PF00328.17 CDJ65217.1 - 9.3e-13 48.2 1.5 9.3e-12 44.9 0.4 4.1 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) ELMO_CED12 PF04727.8 CDJ65218.1 - 7e-25 87.5 0.0 1.1e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family Med3 PF11593.3 CDJ65220.1 - 0.0032 16.7 9.2 0.0032 16.7 6.4 4.0 3 1 1 4 4 4 1 Mediator complex subunit 3 fungal FluMu_gp41 PF10109.4 CDJ65220.1 - 0.043 13.7 0.3 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Mu-like prophage FluMu protein gp41 RAP PF08373.5 CDJ65221.1 - 1.7e-14 53.3 0.0 4.8e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 RAP domain Spt20 PF12090.3 CDJ65221.1 - 0.0044 16.3 2.1 0.11 11.8 0.2 2.3 2 0 0 2 2 2 1 Spt20 family Cellulase-like PF12876.2 CDJ65221.1 - 0.086 13.3 5.3 0.095 13.1 2.2 2.1 2 0 0 2 2 2 0 Sugar-binding cellulase-like DUF2722 PF10846.3 CDJ65221.1 - 0.11 11.5 10.9 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Suf PF05843.9 CDJ65221.1 - 0.24 11.1 8.2 0.32 10.7 2.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AAA_23 PF13476.1 CDJ65221.1 - 0.37 11.0 7.6 0.33 11.2 2.4 2.1 2 0 0 2 2 2 0 AAA domain Pan_kinase PF03309.9 CDJ65221.1 - 0.55 9.7 5.5 0.37 10.2 2.0 1.8 2 0 0 2 2 2 0 Type III pantothenate kinase Med15 PF09606.5 CDJ65221.1 - 0.9 7.6 34.0 0.63 8.1 15.3 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4410 PF14366.1 CDJ65221.1 - 3.7 7.2 6.3 1.9 8.2 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) Gastrin PF00918.12 CDJ65221.1 - 9.6 7.0 17.1 14 6.5 8.9 2.3 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Ofd1_CTDD PF10637.4 CDJ65222.1 - 0.3 10.1 7.1 5.2 6.1 2.2 2.4 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Spt20 PF12090.3 CDJ65225.1 - 1.3 8.3 10.8 0.73 9.1 0.1 3.6 4 0 0 4 4 4 0 Spt20 family DUF2217 PF10265.4 CDJ65225.1 - 1.6 7.4 14.9 0.93 8.1 3.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) SR-25 PF10500.4 CDJ65226.1 - 0.04 13.3 17.4 0.048 13.1 12.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DHHW PF14286.1 CDJ65226.1 - 2.9 7.1 6.0 3 7.0 4.2 1.1 1 0 0 1 1 1 0 DHHW protein DUF3678 PF12435.3 CDJ65226.1 - 3 7.4 15.3 2.1 7.9 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Roughex PF06020.6 CDJ65226.1 - 3.5 6.2 5.2 3.5 6.2 3.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein ORC6 PF05460.8 CDJ65226.1 - 9.2 5.2 12.4 12 4.8 8.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SR-25 PF10500.4 CDJ65227.1 - 0.0052 16.2 5.2 0.0052 16.2 3.6 4.2 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein CYSTM PF12734.2 CDJ65227.1 - 0.011 15.8 5.1 0.011 15.8 3.6 4.1 4 0 0 4 4 4 0 Cysteine-rich TM module stress tolerance Mid2 PF04478.7 CDJ65227.1 - 0.05 13.0 0.0 0.05 13.0 0.0 2.6 4 0 0 4 4 4 0 Mid2 like cell wall stress sensor DUF912 PF06024.7 CDJ65227.1 - 0.36 10.9 0.9 58 3.8 1.6 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2029 PF09594.5 CDJ65227.1 - 1.4 8.3 20.1 0.022 14.2 7.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2029) Spt20 PF12090.3 CDJ65229.1 - 0.0034 16.7 8.8 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 Spt20 family FimP PF09766.4 CDJ65229.1 - 0.63 9.0 13.4 0.81 8.6 4.4 2.2 2 0 0 2 2 2 0 Fms-interacting protein Suf PF05843.9 CDJ65229.1 - 3.2 7.4 13.2 8.1 6.0 0.3 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.1 CDJ65229.1 - 4 6.3 14.3 1.8 7.5 4.2 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cyto_heme_lyase PF01265.12 CDJ65229.1 - 6.4 6.2 11.5 1.5 8.3 3.6 2.2 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase Herpes_gE PF02480.11 CDJ65230.1 - 0.00014 20.2 5.2 0.00014 20.2 3.6 1.9 2 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E Spt20 PF12090.3 CDJ65231.1 - 0.0032 16.8 1.5 0.0039 16.5 1.0 1.2 1 0 0 1 1 1 1 Spt20 family Suf PF05843.9 CDJ65231.1 - 0.0073 16.0 2.4 0.0085 15.8 1.6 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF3046 PF11248.3 CDJ65231.1 - 0.089 12.7 0.2 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) PAT1 PF09770.4 CDJ65231.1 - 0.098 10.8 14.4 0.11 10.6 10.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.4 CDJ65231.1 - 0.26 10.0 2.5 0.36 9.6 1.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4207 PF13904.1 CDJ65231.1 - 0.52 9.6 21.0 1.1 8.5 14.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) DUF4557 PF15101.1 CDJ65231.1 - 0.77 9.5 10.3 1.2 8.9 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) LCD1 PF09798.4 CDJ65231.1 - 0.9 7.4 4.5 1.1 7.1 3.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein BRF1 PF07741.8 CDJ65231.1 - 1.9 8.7 7.3 3.6 7.8 5.0 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain SR-25 PF10500.4 CDJ65231.1 - 2.9 7.3 24.2 2 7.7 8.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ65231.1 - 3.2 6.7 13.2 4.4 6.2 9.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein eIF3_subunit PF08597.5 CDJ65231.1 - 5.6 6.4 9.3 8.1 5.9 6.5 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DivIC PF04977.10 CDJ65231.1 - 8.4 5.9 12.5 12 5.4 8.6 1.2 1 0 0 1 1 1 0 Septum formation initiator Topoisom_I_N PF02919.10 CDJ65232.1 - 3.8e-82 274.7 1.1 2.3e-57 193.7 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CDJ65232.1 - 1.3e-65 220.7 11.3 6.9e-42 143.1 0.4 2.8 1 1 1 2 2 2 2 Eukaryotic DNA topoisomerase I, catalytic core Sas10_Utp3 PF04000.10 CDJ65234.1 - 1.9e-07 31.1 0.0 1.9e-07 31.1 0.0 3.6 3 1 0 3 3 3 1 Sas10/Utp3/C1D family CAF-1_p150 PF11600.3 CDJ65234.1 - 0.29 10.4 25.4 0.51 9.6 17.6 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 CDJ65234.1 - 0.34 8.9 15.5 0.44 8.5 10.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CDJ65234.1 - 0.53 8.4 24.4 0.06 11.6 13.9 1.5 2 0 0 2 2 2 0 Transmembrane protein CDC45 PF02724.9 CDJ65234.1 - 1.1 7.2 14.5 1.6 6.6 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.14 CDJ65234.1 - 1.9 8.9 26.3 0.38 11.1 11.0 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2217 PF10265.4 CDJ65234.1 - 4.5 5.9 14.7 6.4 5.4 10.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SWIB PF02201.13 CDJ65235.1 - 1.1e-10 41.0 0.1 2.6e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain PP2C PF00481.16 CDJ65235.1 - 3.9e-08 33.0 4.0 3.5e-05 23.3 0.0 3.5 4 1 0 5 5 5 2 Protein phosphatase 2C Corona_nucleoca PF00937.13 CDJ65235.1 - 0.0027 16.7 5.1 0.0027 16.7 3.6 7.8 3 2 5 8 8 8 1 Coronavirus nucleocapsid protein P12 PF12669.2 CDJ65236.1 - 0.13 12.4 4.3 0.13 12.4 3.0 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family FimP PF09766.4 CDJ65236.1 - 0.16 10.9 7.2 0.13 11.3 5.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDJ65236.1 - 0.61 9.4 6.9 0.53 9.6 4.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF913 PF06025.7 CDJ65236.1 - 0.88 8.2 5.1 0.92 8.1 3.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ERF PF04404.7 CDJ65236.1 - 1 8.8 9.8 1.1 8.8 6.8 1.2 1 0 0 1 1 1 0 ERF superfamily DUF1071 PF06378.6 CDJ65236.1 - 1.6 7.8 4.6 1.7 7.7 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) PAT1 PF09770.4 CDJ65236.1 - 1.7 6.7 16.7 1.5 6.9 11.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4661 PF15576.1 CDJ65236.1 - 1.9 8.0 5.6 2 8.0 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Suf PF05843.9 CDJ65236.1 - 4.7 6.8 8.7 4.2 7.0 6.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF788 PF05620.6 CDJ65236.1 - 4.7 7.0 6.5 5 6.9 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) WD40 PF00400.27 CDJ65237.1 - 1.9e-13 49.7 2.6 3.5e-07 29.8 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Hid1 PF12722.2 CDJ65238.1 - 0.0046 14.7 16.7 0.0052 14.5 11.6 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein SGT1 PF07093.6 CDJ65238.1 - 0.026 12.9 17.3 0.035 12.5 12.0 1.3 1 0 0 1 1 1 0 SGT1 protein Herpes_UL87 PF03043.9 CDJ65238.1 - 0.63 8.3 9.6 0.68 8.2 6.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF342 PF03961.8 CDJ65238.1 - 1.1 7.6 19.5 1.4 7.2 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AvrE PF11725.3 CDJ65238.1 - 2 5.3 26.5 2.5 5.0 18.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor PAT1 PF09770.4 CDJ65238.1 - 2.4 6.2 80.1 3.2 5.8 55.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDJ65238.1 - 2.6 7.9 26.2 4.2 7.2 18.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 CDJ65238.1 - 3.2 6.9 23.5 4.3 6.5 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nha1_C PF08619.5 CDJ65238.1 - 7.2 5.7 26.2 9.9 5.3 18.1 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Zip PF02535.17 CDJ65238.1 - 7.9 5.3 6.3 12 4.7 4.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 CDJ65238.1 - 9.5 4.9 23.0 14 4.4 15.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Cullin_Nedd8 PF10557.4 CDJ65239.1 - 3e-15 55.7 0.0 3.3e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3658 PF12395.3 CDJ65239.1 - 0.063 12.8 0.0 0.067 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function Sirohm_synth_M PF14824.1 CDJ65239.1 - 0.097 11.6 0.9 0.23 10.4 0.6 1.7 1 1 0 1 1 1 0 Sirohaem biosynthesis protein central Myosin_TH1 PF06017.8 CDJ65240.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Myosin tail SNAP PF14938.1 CDJ65241.1 - 2.1e-47 161.6 29.4 3.3e-28 98.6 4.6 2.0 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP MSP1_C PF07462.6 CDJ65241.1 - 0.97 7.7 3.7 1.4 7.2 2.6 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SprA-related PF12118.3 CDJ65242.1 - 0.0009 18.6 44.8 0.0009 18.6 31.1 13.5 6 3 5 13 13 13 1 SprA-related family CAF-1_p150 PF11600.3 CDJ65242.1 - 0.0034 16.7 27.8 0.0034 16.7 19.3 9.8 8 1 2 10 10 10 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_hydro_9 PF00759.14 CDJ65244.1 - 0.092 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 GHMP_kinases_N PF00288.21 CDJ65246.1 - 3.2 7.9 11.9 0.078 13.0 2.3 2.7 3 0 0 3 3 3 0 GHMP kinases N terminal domain PAS PF00989.19 CDJ65246.1 - 9.4 6.0 7.5 1.8 8.4 0.7 2.5 2 0 0 2 2 2 0 PAS fold mRNA_cap_enzyme PF01331.14 CDJ65247.1 - 6e-37 127.2 0.0 7.8e-35 120.3 0.0 2.7 1 1 1 2 2 2 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 CDJ65247.1 - 3.5e-05 23.2 0.3 0.0017 17.7 0.2 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Cpn60_TCP1 PF00118.19 CDJ65249.1 - 5.9e-41 140.6 0.2 7.1e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3883 PF13020.1 CDJ65250.1 - 4.2e-06 26.3 0.0 6.3e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) BT1 PF03092.11 CDJ65251.1 - 6.5e-67 226.1 14.7 1.3e-66 225.1 10.2 1.4 1 1 0 1 1 1 1 BT1 family tRNA-synt_2c PF01411.14 CDJ65254.1 - 3.8e-197 655.9 0.0 4.7e-197 655.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CDJ65254.1 - 2.8e-14 52.6 0.1 6.4e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CDJ65254.1 - 0.0034 17.0 1.1 0.011 15.3 0.1 2.4 2 0 0 2 2 2 1 DHHA1 domain RRM_1 PF00076.17 CDJ65255.1 - 6.8e-29 99.3 0.1 9.2e-17 60.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ65255.1 - 8.1e-24 83.3 0.0 3.4e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ65255.1 - 0.0001 22.1 0.0 0.00038 20.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Miro PF08477.8 CDJ65256.1 - 0.044 14.2 0.0 0.36 11.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Adeno_E3_CR2 PF02439.10 CDJ65259.1 - 0.15 11.6 0.4 0.26 10.8 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Radical_SAM PF04055.16 CDJ65260.1 - 3.9e-17 62.9 0.0 1.3e-16 61.2 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CDJ65260.1 - 0.0038 17.2 0.3 0.027 14.4 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_transf_9 PF01075.12 CDJ65260.1 - 0.021 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) UCH PF00443.24 CDJ65261.1 - 1.2e-13 50.8 0.0 1.2e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase tRNA-synt_2 PF00152.15 CDJ65262.1 - 5.9e-87 291.5 0.0 7.7e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CDJ65262.1 - 5e-10 39.1 0.0 9.5e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CDJ65262.1 - 8.8e-08 31.6 0.0 3.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CDJ65262.1 - 0.0017 17.9 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 CDJ65265.1 - 2.9e-06 26.9 1.8 0.57 10.1 0.0 5.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Spt20 PF12090.3 CDJ65267.1 - 0.018 14.3 2.2 0.025 13.9 1.5 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDJ65267.1 - 0.039 13.6 7.9 0.056 13.1 5.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ctr PF04145.10 CDJ65267.1 - 0.4 10.7 4.4 0.34 10.9 1.2 2.2 2 1 0 2 2 2 0 Ctr copper transporter family DUF4557 PF15101.1 CDJ65267.1 - 0.48 10.2 8.9 0.77 9.5 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 CDJ65267.1 - 0.98 7.0 18.8 1.5 6.3 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RAB3GAP2_N PF14655.1 CDJ65267.1 - 1.2 8.0 5.5 2 7.3 3.8 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1631 PF07793.6 CDJ65267.1 - 8.5 4.3 17.6 0.58 8.2 8.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Chromo PF00385.19 CDJ65268.1 - 1.6e-07 30.8 0.1 3.9e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NODP PF07684.7 CDJ65269.1 - 1.3 8.6 6.0 2.8 7.6 4.2 1.5 1 0 0 1 1 1 0 NOTCH protein Citrate_synt PF00285.16 CDJ65269.1 - 5.9 5.5 6.7 7.9 5.1 4.7 1.2 1 0 0 1 1 1 0 Citrate synthase Med15 PF09606.5 CDJ65271.1 - 0.044 12.0 13.0 0.053 11.7 9.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF572 PF04502.8 CDJ65271.1 - 0.087 12.0 9.8 0.11 11.6 6.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Phostensin_N PF13916.1 CDJ65271.1 - 0.14 12.1 5.8 0.28 11.1 4.0 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal APC_CDC26 PF10471.4 CDJ65271.1 - 0.17 12.6 18.7 0.36 11.5 8.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 BAF1_ABF1 PF04684.8 CDJ65271.1 - 0.72 8.6 18.4 0.05 12.4 8.9 1.6 1 1 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Bul1_C PF04426.7 CDJ65271.1 - 4.2 6.4 9.9 0.46 9.6 0.7 2.0 2 0 0 2 2 2 0 Bul1 C terminus Peptidase_S64 PF08192.6 CDJ65271.1 - 5.7 5.1 14.2 6.9 4.8 9.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4175 PF13779.1 CDJ65272.1 - 0.056 11.1 13.0 0.075 10.7 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PLRV_ORF5 PF01690.12 CDJ65272.1 - 1.6 7.8 23.2 1.9 7.5 16.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Helicase_C PF00271.26 CDJ65273.1 - 5.1e-15 55.1 0.0 5.1e-15 55.1 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SAPS PF04499.10 CDJ65273.1 - 2.7 6.5 26.6 1.1 7.7 4.4 2.5 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 CDJ65273.1 - 3.5 6.9 41.1 0.25 10.6 5.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 CDJ65274.1 - 3.1e-51 174.0 0.0 4.3e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65274.1 - 1.8e-48 164.8 0.0 3.3e-48 164.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ65274.1 - 6.1e-05 22.1 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDJ65274.1 - 0.0021 17.8 1.5 0.0052 16.5 0.7 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CDJ65274.1 - 0.0029 16.6 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Transglut_core3 PF13471.1 CDJ65274.1 - 0.0091 15.7 1.7 0.015 15.1 0.3 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily Med15 PF09606.5 CDJ65274.1 - 6.5 4.8 16.2 1.4 7.0 2.2 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ65276.1 - 1.3 9.4 4.3 3.9 7.9 0.6 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ65277.1 - 0.012 15.1 6.0 0.012 15.1 4.1 4.5 4 2 0 5 5 5 0 Nuclear RNA-splicing-associated protein DUF3449 PF11931.3 CDJ65278.1 - 3.3e-63 212.7 15.9 3.2e-53 180.1 0.5 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF3449) DUF3738 PF12543.3 CDJ65278.1 - 0.026 14.0 0.9 5.1 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3738) Desulfoferrod_N PF06397.7 CDJ65278.1 - 0.065 12.6 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain TPR_8 PF13181.1 CDJ65278.1 - 0.11 12.2 2.1 16 5.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PAP_RNA-bind PF04926.10 CDJ65278.1 - 0.13 11.7 1.5 3.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain Herpes_env PF01673.13 CDJ65278.1 - 1.9 6.9 7.8 2.5 6.5 5.4 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Syntaxin PF00804.20 CDJ65278.1 - 2.9 8.1 18.4 4.7 7.4 3.0 2.3 1 1 1 2 2 2 0 Syntaxin ADIP PF11559.3 CDJ65278.1 - 3.3 7.5 23.2 4.7 7.1 4.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FATC PF02260.15 CDJ65279.1 - 0.059 12.8 0.1 0.094 12.1 0.1 1.2 1 0 0 1 1 1 0 FATC domain ETRAMP PF09716.5 CDJ65280.1 - 6.2 6.8 0.0 6.2 6.8 0.0 5.9 5 3 1 6 6 6 0 Malarial early transcribed membrane protein (ETRAMP) SR-25 PF10500.4 CDJ65280.1 - 6.7 6.1 97.6 7 6.0 15.6 4.2 2 2 1 3 3 3 0 Nuclear RNA-splicing-associated protein BT1 PF03092.11 CDJ65282.1 - 3.3e-07 29.3 1.1 0.0025 16.5 0.0 2.2 2 0 0 2 2 2 2 BT1 family MFS_2 PF13347.1 CDJ65282.1 - 2.4 6.4 10.3 1 7.6 2.3 2.2 1 1 1 2 2 2 0 MFS/sugar transport protein Prominin PF05478.6 CDJ65282.1 - 2.9 5.2 6.1 0.86 7.0 2.3 1.4 2 0 0 2 2 2 0 Prominin STT3 PF02516.9 CDJ65283.1 - 5.3e-27 94.9 22.6 7e-27 94.5 15.7 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.4 CDJ65283.1 - 2.1 6.3 6.1 3.7 5.6 4.2 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation STT3 PF02516.9 CDJ65284.1 - 5.1e-49 167.5 30.6 1.4e-48 166.0 21.2 1.6 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Gryzun PF07919.7 CDJ65285.1 - 5e-07 28.4 0.2 8e-07 27.7 0.1 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi NolV PF06635.7 CDJ65285.1 - 0.035 13.2 0.8 0.074 12.2 0.6 1.4 1 0 0 1 1 1 0 Nodulation protein NolV WD40 PF00400.27 CDJ65286.1 - 2.4e-06 27.2 1.7 4e-05 23.3 0.2 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat F-box PF00646.28 CDJ65286.1 - 0.00049 19.6 0.1 0.025 14.2 0.0 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 CDJ65286.1 - 0.0027 17.4 0.3 0.012 15.3 0.2 2.2 1 0 0 1 1 1 1 F-box-like RNA_GG_bind PF10258.4 CDJ65287.1 - 0.062 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 PHAX RNA-binding domain FUSC_2 PF13515.1 CDJ65288.1 - 5.6e-13 48.9 7.7 5.6e-13 48.9 5.3 3.6 3 1 1 4 4 4 1 Fusaric acid resistance protein-like MMtag PF10159.4 CDJ65289.1 - 2.9e-15 56.0 3.2 2.9e-15 56.0 2.2 4.7 4 1 0 4 4 4 1 Kinase phosphorylation protein E1-E2_ATPase PF00122.15 CDJ65290.1 - 1e-56 191.5 0.3 4.4e-56 189.4 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDJ65290.1 - 5e-35 120.6 1.5 5e-35 120.6 1.0 3.7 5 0 0 5 5 5 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDJ65290.1 - 4.8e-25 89.2 0.0 3.7e-24 86.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ65290.1 - 6.7e-14 52.4 0.1 2.1e-13 50.8 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDJ65290.1 - 4.9e-13 48.8 0.0 1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CDJ65290.1 - 7e-08 31.8 0.1 3.1e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CDJ65290.1 - 2.7e-05 23.8 0.5 0.0015 18.1 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IncA PF04156.9 CDJ65290.1 - 0.13 11.7 0.0 0.38 10.3 0.0 1.8 1 0 0 1 1 1 0 IncA protein AMP-binding PF00501.23 CDJ65291.1 - 6.4e-85 285.0 0.2 2.2e-81 273.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CDJ65291.1 - 7.6e-22 78.0 0.5 3.4e-21 75.9 0.3 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RNA_pol_3_Rpc31 PF11705.3 CDJ65293.1 - 0.0036 17.2 18.8 0.085 12.7 13.0 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.5 CDJ65293.1 - 0.0077 16.8 3.0 0.014 16.0 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) Ricin_B_lectin PF00652.17 CDJ65294.1 - 0.046 13.7 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Atg14 PF10186.4 CDJ65295.1 - 0.045 12.6 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NARP1 PF12569.3 CDJ65297.1 - 1.1e-103 347.7 25.2 5.7e-79 266.2 10.1 4.0 4 0 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CDJ65297.1 - 1.5e-17 62.9 18.5 1.5e-05 24.5 0.0 6.9 6 1 1 7 7 7 3 TPR repeat TPR_1 PF00515.23 CDJ65297.1 - 5.8e-12 44.6 12.9 3.3e-05 23.2 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ65297.1 - 1e-10 41.9 20.1 0.0015 19.1 0.1 6.8 8 0 0 8 8 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ65297.1 - 1.5e-08 34.1 9.5 0.079 13.1 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ65297.1 - 2.3e-08 33.9 15.9 0.016 15.7 0.0 8.7 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ65297.1 - 3.9e-08 32.6 33.7 2.9e-05 23.6 0.0 9.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ65297.1 - 7e-08 32.2 21.2 6.3e-05 22.8 1.4 6.1 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ65297.1 - 1.2e-05 25.4 10.0 3.7 8.2 0.0 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ65297.1 - 5.8e-05 22.5 7.5 0.2 11.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ65297.1 - 6.2e-05 22.7 1.8 10 6.0 0.1 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ65297.1 - 0.00017 21.1 18.1 0.006 16.2 0.0 6.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ65297.1 - 0.00019 21.6 10.6 0.25 11.7 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Glyco_hydro_65m PF03632.10 CDJ65297.1 - 0.0036 16.0 0.0 0.0063 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain PseudoU_synth_2 PF00849.17 CDJ65298.1 - 8.1e-21 74.5 0.1 3.2e-20 72.6 0.0 2.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase OTU PF02338.14 CDJ65299.1 - 2.6e-06 28.0 0.0 2.7e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease PilO PF04350.8 CDJ65299.1 - 0.13 12.1 0.3 0.21 11.4 0.2 1.2 1 0 0 1 1 1 0 Pilus assembly protein, PilO BT1 PF03092.11 CDJ65301.1 - 1.9e-79 267.4 21.3 2.9e-79 266.8 14.8 1.2 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CDJ65301.1 - 1.3e-12 47.1 36.6 4.4e-07 28.9 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Evr1_Alr PF04777.8 CDJ65302.1 - 1.2e-11 44.3 0.0 5.4e-11 42.2 0.1 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Nop52 PF05997.7 CDJ65304.1 - 1.9e-39 135.3 0.4 2.9e-39 134.7 0.3 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Abhydrolase_3 PF07859.8 CDJ65305.1 - 7.9e-37 126.8 0.0 1.2e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CDJ65305.1 - 8.1e-08 31.4 0.2 2.3e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 CDJ65305.1 - 1.3e-05 24.0 0.0 2.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 CDJ65305.1 - 0.00042 19.5 0.0 0.0065 15.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDJ65305.1 - 0.0027 17.4 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chorein_N PF12624.2 CDJ65306.1 - 2.7e-30 104.3 0.0 6.8e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CDJ65306.1 - 4.4e-06 26.1 0.0 2.2e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 CDJ65306.1 - 0.0019 18.3 0.0 0.009 16.1 0.0 2.2 1 0 0 1 1 1 1 ATG C terminal domain DUF570 PF04489.8 CDJ65306.1 - 0.62 8.4 0.0 0.98 7.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Apt1 PF10351.4 CDJ65306.1 - 1.6 7.5 0.6 82 1.8 1.1 2.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain PBP5_C PF07943.8 CDJ65306.1 - 4 7.5 0.0 8.7 6.4 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein 5, C-terminal domain Ist1 PF03398.9 CDJ65307.1 - 5.8e-33 113.6 1.1 8.2e-33 113.1 0.7 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF1586 PF07625.6 CDJ65307.1 - 0.17 11.6 0.9 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) BAF1_ABF1 PF04684.8 CDJ65309.1 - 0.079 11.7 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BPL_LplA_LipB PF03099.14 CDJ65312.1 - 1.7e-12 47.4 0.4 4.2e-12 46.1 0.3 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CDJ65312.1 - 0.00014 21.4 0.0 0.00035 20.1 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain RAP1 PF07218.6 CDJ65313.1 - 0.91 7.5 3.6 1.4 6.8 2.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Vma12 PF11712.3 CDJ65313.1 - 2.1 8.0 9.2 7.6 6.2 1.5 2.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-like PF04071.7 CDJ65316.1 - 0.036 13.7 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich small domain DUF3133 PF11331.3 CDJ65316.1 - 0.062 12.8 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) Fibroin_P25 PF07294.6 CDJ65318.1 - 0.014 14.9 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Fibroin P25 DUF3752 PF12572.3 CDJ65319.1 - 2.9e-07 30.7 10.4 2.9e-07 30.7 7.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) Actin PF00022.14 CDJ65320.1 - 1.1e-70 238.0 0.0 2.7e-70 236.7 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CDJ65320.1 - 0.34 9.4 0.7 7.4 5.0 0.0 2.8 3 0 0 3 3 3 0 MreB/Mbl protein Dynamitin PF04912.9 CDJ65321.1 - 5.1e-31 107.8 9.0 3.9e-14 52.2 1.4 3.8 4 0 0 4 4 4 3 Dynamitin NPV_P10 PF05531.7 CDJ65321.1 - 0.38 11.0 2.5 5.2 7.3 0.0 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 CDJ65321.1 - 0.63 9.8 7.8 0.76 9.5 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 CDJ65321.1 - 2.9 5.6 7.3 0.53 8.0 0.7 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family zf-C3HC4 PF00097.20 CDJ65322.1 - 9.5e-07 28.3 7.9 2e-06 27.3 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CDJ65322.1 - 2.1e-05 24.1 4.3 4.4e-05 23.1 3.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 CDJ65322.1 - 4.8e-05 23.3 9.9 9.6e-05 22.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ65322.1 - 0.00023 20.8 8.7 0.00049 19.7 6.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CDJ65322.1 - 0.00035 20.4 10.2 0.00073 19.3 7.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CDJ65322.1 - 0.00076 19.2 9.8 0.0018 18.0 6.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CDJ65322.1 - 0.0011 18.6 7.0 0.0023 17.5 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CDJ65322.1 - 0.0068 15.9 3.6 0.02 14.4 2.5 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CDJ65322.1 - 0.018 14.7 1.7 0.047 13.4 1.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PyrI_C PF02748.10 CDJ65322.1 - 0.16 11.4 3.6 4.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain OmpH PF03938.9 CDJ65322.1 - 6.9 6.5 13.2 2.2 8.2 7.1 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-RING_4 PF14570.1 CDJ65327.1 - 3.8e-19 67.9 10.4 7.7e-19 67.0 7.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 CDJ65327.1 - 3.7e-06 26.4 0.0 8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ65327.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CDJ65327.1 - 3.9e-05 23.2 7.2 7.9e-05 22.2 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 CDJ65327.1 - 0.00033 20.5 0.0 0.00069 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 CDJ65327.1 - 0.023 14.4 3.8 0.083 12.6 2.7 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 CDJ65327.1 - 0.15 11.7 3.3 0.31 10.7 2.3 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 CDJ65327.1 - 0.32 10.9 8.4 0.97 9.3 5.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING GRIM-19 PF06212.7 CDJ65329.1 - 1.7 8.3 8.3 0.54 9.9 3.1 2.0 1 1 1 2 2 2 0 GRIM-19 protein Cut12 PF11500.3 CDJ65329.1 - 5.6 6.6 15.1 16 5.1 10.4 1.8 1 0 0 1 1 1 0 Spindle pole body formation-associated protein CAF-1_p150 PF11600.3 CDJ65329.1 - 7.5 5.8 18.2 17 4.6 12.6 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal V-SNARE_C PF12352.3 CDJ65331.1 - 0.0023 17.9 0.3 0.0023 17.9 0.2 3.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF3433 PF11915.3 CDJ65331.1 - 0.067 13.3 0.5 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) Pkinase PF00069.20 CDJ65332.1 - 1.5e-15 57.0 0.0 1.7e-13 50.3 0.0 2.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65332.1 - 4.2e-09 35.8 0.0 4.2e-09 35.8 0.0 2.8 4 0 0 4 4 4 1 Protein tyrosine kinase SPC12 PF06645.8 CDJ65334.1 - 3.8e-19 68.2 0.2 5e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) UPF0104 PF03706.8 CDJ65334.1 - 0.0023 17.2 0.0 0.0026 17.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) Big_5 PF13205.1 CDJ65335.1 - 7.4e-10 39.3 0.0 0.0072 16.9 0.0 4.3 2 2 0 2 2 2 2 Bacterial Ig-like domain Notch PF00066.12 CDJ65335.1 - 7.9e-07 29.2 8.2 7.9e-07 29.2 5.6 3.6 2 0 0 2 2 2 1 LNR domain UPF0104 PF03706.8 CDJ65335.1 - 0.43 9.8 0.1 0.71 9.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) BatD PF13584.1 CDJ65335.1 - 0.89 8.0 0.0 1.5 7.3 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance SHR3_chaperone PF08229.6 CDJ65335.1 - 1.1 8.1 3.6 1.2 8.1 1.2 2.0 2 0 0 2 2 2 0 ER membrane protein SH3 Ctr PF04145.10 CDJ65335.1 - 2.7 8.0 1.4 37 4.3 0.0 3.0 3 0 0 3 3 3 0 Ctr copper transporter family Rifin_STEVOR PF02009.11 CDJ65335.1 - 5.1 6.6 0.0 16 4.9 0.0 1.8 1 0 0 1 1 1 0 Rifin/stevor family AP2 PF00847.15 CDJ65336.1 - 8.7e-07 29.0 0.2 8.7e-07 29.0 0.2 6.8 10 0 0 10 10 10 1 AP2 domain ACDC PF14733.1 CDJ65336.1 - 0.32 11.1 0.0 0.73 10.0 0.0 1.6 1 0 0 1 1 1 0 AP2-coincident C-terminal AP2 PF00847.15 CDJ65337.1 - 0.0023 18.0 0.1 0.0023 18.0 0.1 3.9 5 0 0 5 5 5 1 AP2 domain RP-C_C PF11800.3 CDJ65338.1 - 0.091 12.4 6.6 0.096 12.3 0.6 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Sec3_C PF09763.4 CDJ65338.1 - 0.3 9.1 8.1 1.6 6.7 1.4 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 DUF572 PF04502.8 CDJ65338.1 - 1.1 8.4 16.7 0.61 9.2 2.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF566 PF04484.7 CDJ65338.1 - 1.9 7.9 23.8 0.46 9.9 5.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF566) Macoilin PF09726.4 CDJ65338.1 - 2.1 6.5 23.4 0.25 9.5 4.9 2.0 2 0 0 2 2 2 0 Transmembrane protein Ndc1_Nup PF09531.5 CDJ65338.1 - 2.9 6.1 12.3 0.41 9.0 1.1 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.4 CDJ65338.1 - 3.1 6.5 22.0 1 8.1 4.9 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain NPR3 PF03666.8 CDJ65338.1 - 4 5.8 16.6 0.14 10.6 1.2 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Lin-8 PF03353.10 CDJ65338.1 - 5.5 6.1 11.5 3.4 6.8 1.3 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.2 CDJ65338.1 - 5.8 4.4 6.7 2.3 5.8 0.4 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein NARP1 PF12569.3 CDJ65338.1 - 7.1 5.2 6.3 14 4.2 4.4 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_A12 PF04651.8 CDJ65338.1 - 9.1 6.3 22.0 2.2 8.3 4.7 2.5 3 0 0 3 3 2 0 Poxvirus A12 protein Inp1 PF12634.2 CDJ65338.1 - 9.4 5.8 10.7 5 6.7 0.9 2.4 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 Ank PF00023.25 CDJ65341.1 - 1.4e-11 43.5 0.3 5.8e-05 22.7 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CDJ65341.1 - 2e-11 44.0 0.1 9.7e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDJ65341.1 - 2.3e-10 40.3 1.5 6.9e-07 29.3 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ65341.1 - 1.3e-09 37.3 0.1 0.0063 16.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CDJ65341.1 - 3e-09 37.1 0.1 6.2e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RWD PF05773.17 CDJ65342.1 - 0.26 11.1 1.5 1.4 8.8 1.1 1.9 1 1 0 1 1 1 0 RWD domain DUF1645 PF07816.6 CDJ65342.1 - 7.4 6.9 9.2 28 5.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) mRNA_triPase PF02940.10 CDJ65344.1 - 0.0061 16.3 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PP2C PF00481.16 CDJ65345.1 - 4.4e-10 39.3 4.4 3.4e-06 26.6 0.2 3.4 2 1 1 3 3 3 3 Protein phosphatase 2C Ribosomal_60s PF00428.14 CDJ65345.1 - 0.011 16.0 11.3 0.011 16.0 7.8 5.6 3 1 0 3 3 3 0 60s Acidic ribosomal protein FAM60A PF15396.1 CDJ65345.1 - 1.2 8.8 6.2 13 5.4 5.2 1.9 2 0 0 2 2 2 0 Protein Family FAM60A DUF1675 PF07897.6 CDJ65345.1 - 5.8 6.6 15.6 10 5.8 10.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hid1 PF12722.2 CDJ65345.1 - 7.6 4.0 11.4 10 3.6 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPR_2 PF13041.1 CDJ65346.1 - 3.4e-25 87.7 0.0 1.5e-05 24.8 0.0 6.3 3 1 4 7 7 7 6 PPR repeat family PPR_3 PF13812.1 CDJ65346.1 - 1.9e-16 58.8 38.3 0.00011 22.2 0.1 10.0 10 0 0 10 10 10 6 Pentatricopeptide repeat domain PPR PF01535.15 CDJ65346.1 - 3.4e-09 36.0 0.0 2.9 8.0 0.0 6.2 7 0 0 7 7 7 4 PPR repeat PPR_1 PF12854.2 CDJ65346.1 - 1.3e-06 27.8 0.0 2.9 7.4 0.0 6.2 9 0 0 9 9 9 2 PPR repeat Lebercilin PF15619.1 CDJ65347.1 - 0.00025 20.5 5.4 0.00029 20.3 3.8 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF1151 PF06625.6 CDJ65347.1 - 0.0036 17.0 7.6 0.0042 16.7 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1151) Jnk-SapK_ap_N PF09744.4 CDJ65347.1 - 0.18 11.7 5.2 0.21 11.5 3.6 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4557 PF15101.1 CDJ65347.1 - 0.54 10.0 7.3 0.65 9.7 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Mnd1 PF03962.10 CDJ65347.1 - 0.75 9.4 9.8 0.89 9.1 6.8 1.0 1 0 0 1 1 1 0 Mnd1 family DUF3584 PF12128.3 CDJ65347.1 - 1.3 6.3 11.3 1.5 6.0 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YlqD PF11068.3 CDJ65347.1 - 3.5 7.6 8.4 4.8 7.2 5.8 1.2 1 0 0 1 1 1 0 YlqD protein DUF2360 PF10152.4 CDJ65347.1 - 6.6 7.0 8.7 8.1 6.7 6.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SAGA-Tad1 PF12767.2 CDJ65348.1 - 0.041 13.5 31.3 0.056 13.1 21.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2201_N PF13203.1 CDJ65348.1 - 0.071 12.2 29.9 0.084 12.0 20.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain FAM60A PF15396.1 CDJ65348.1 - 0.11 12.2 24.2 0.14 11.9 16.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BTV_NS2 PF04514.7 CDJ65348.1 - 0.16 10.8 20.1 0.18 10.6 13.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DDRGK PF09756.4 CDJ65348.1 - 0.27 10.6 37.7 0.37 10.1 26.1 1.2 1 0 0 1 1 1 0 DDRGK domain Spc7_N PF15402.1 CDJ65348.1 - 0.31 9.0 27.1 0.37 8.7 18.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SAPS PF04499.10 CDJ65348.1 - 0.5 8.9 24.3 0.52 8.8 16.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein WTX PF09422.5 CDJ65348.1 - 0.6 8.9 17.1 0.62 8.9 11.9 1.1 1 0 0 1 1 1 0 WTX protein Ndc1_Nup PF09531.5 CDJ65348.1 - 0.63 8.3 31.6 0.71 8.2 21.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GAGA_bind PF06217.7 CDJ65348.1 - 0.84 9.5 29.9 0.98 9.3 20.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family HCO3_cotransp PF00955.16 CDJ65348.1 - 1.1 7.8 8.1 1.4 7.4 5.6 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF4045 PF13254.1 CDJ65348.1 - 1.2 8.3 26.6 1.4 8.1 18.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDJ65348.1 - 1.3 8.0 27.0 1.5 7.8 18.7 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ycf1 PF05758.7 CDJ65348.1 - 1.6 6.3 29.5 1.8 6.2 20.5 1.1 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CDJ65348.1 - 2.5 7.9 23.0 3 7.6 15.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2146 PF10220.4 CDJ65348.1 - 3 5.7 23.4 3.5 5.5 16.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Presenilin PF01080.12 CDJ65348.1 - 3.2 6.4 20.6 3.6 6.3 14.3 1.0 1 0 0 1 1 1 0 Presenilin Dapper PF15268.1 CDJ65348.1 - 3.3 6.4 36.5 3.4 6.3 25.3 1.0 1 0 0 1 1 1 0 Dapper Cellulose_synt PF03552.9 CDJ65348.1 - 3.7 5.7 13.7 4.7 5.3 9.5 1.2 1 0 0 1 1 1 0 Cellulose synthase PAT1 PF09770.4 CDJ65348.1 - 3.8 5.6 79.1 4.5 5.4 54.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Raftlin PF15250.1 CDJ65348.1 - 4 5.8 28.6 5 5.5 19.8 1.1 1 0 0 1 1 1 0 Raftlin Draxin PF15550.1 CDJ65348.1 - 4.6 6.8 23.2 5.9 6.4 16.1 1.2 1 0 0 1 1 1 0 Draxin Utp14 PF04615.8 CDJ65348.1 - 6.1 4.8 38.0 7.4 4.5 26.4 1.0 1 0 0 1 1 1 0 Utp14 protein FLO_LFY PF01698.11 CDJ65348.1 - 6.3 5.5 27.4 9.1 5.0 19.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Exonuc_VII_L PF02601.10 CDJ65348.1 - 9.5 5.3 30.7 11 5.0 21.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit SR-25 PF10500.4 CDJ65349.1 - 0.0017 17.8 8.7 0.0017 17.8 6.0 2.7 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ65349.1 - 0.57 10.2 29.8 0.021 14.9 10.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF755) Herpes_UL87 PF03043.9 CDJ65349.1 - 1.9 6.7 9.7 4.6 5.5 6.7 1.6 1 1 0 1 1 1 0 Herpesvirus UL87 family DUF342 PF03961.8 CDJ65349.1 - 5.4 5.3 7.3 9.2 4.5 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4207 PF13904.1 CDJ65350.1 - 0.54 9.5 19.2 0.61 9.4 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF3450 PF11932.3 CDJ65350.1 - 6 6.0 23.8 7 5.8 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Presenilin PF01080.12 CDJ65350.1 - 8.4 5.0 7.2 9.1 4.9 5.0 1.0 1 0 0 1 1 1 0 Presenilin Glyco_transf_7C PF02709.9 CDJ65352.1 - 3.8e-05 23.0 0.0 7.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 CDJ65352.1 - 0.0042 16.4 3.6 0.0042 16.4 2.5 2.7 2 1 1 3 3 3 1 N-terminal region of glycosyl transferase group 7 Gastrin PF00918.12 CDJ65352.1 - 0.025 15.4 1.2 0.025 15.4 0.8 5.1 3 1 1 4 4 4 0 Gastrin/cholecystokinin family GAS PF13851.1 CDJ65353.1 - 0.11 11.6 24.8 0.3 10.2 5.4 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Ras PF00071.17 CDJ65354.1 - 5.1e-44 149.5 0.1 5.9e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ65354.1 - 3.2e-19 69.5 0.0 4.1e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDJ65354.1 - 1.6e-12 46.9 0.0 2e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CDJ65354.1 - 6.6e-08 32.5 0.0 7.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CDJ65354.1 - 2.9e-06 26.5 0.0 3.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDJ65354.1 - 1.2e-05 24.8 0.0 0.00087 18.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CDJ65354.1 - 0.00088 18.5 0.0 0.001 18.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CDJ65354.1 - 0.01 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 CDJ65354.1 - 0.011 14.7 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Septin MobB PF03205.9 CDJ65354.1 - 0.025 14.2 0.1 0.036 13.7 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CDJ65354.1 - 0.03 13.5 0.1 0.049 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDJ65354.1 - 0.034 14.2 0.0 0.04 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CDJ65354.1 - 0.059 12.6 0.2 0.2 10.9 0.1 1.9 2 1 1 3 3 3 0 Ferrous iron transport protein B PduV-EutP PF10662.4 CDJ65354.1 - 0.071 12.5 0.1 0.098 12.1 0.1 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SIR2 PF02146.12 CDJ65355.1 - 6.1e-47 159.6 0.0 7.6e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CDJ65355.1 - 1.1e-07 31.6 0.0 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain GMC_oxred_C PF05199.8 CDJ65357.1 - 3.6e-21 75.9 0.0 3.4e-16 59.8 0.0 2.6 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.14 CDJ65357.1 - 1.6e-09 37.3 0.1 2.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Ribosomal_L22 PF00237.14 CDJ65359.1 - 8.8e-22 77.0 0.4 1.2e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ELFV_dehydrog PF00208.16 CDJ65360.1 - 1.7e-78 263.6 0.9 2.1e-78 263.2 0.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CDJ65360.1 - 3.2e-47 159.3 0.0 9.1e-47 157.9 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 CDJ65360.1 - 0.00061 20.0 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 CDJ65360.1 - 0.024 13.7 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 CDJ65360.1 - 0.083 12.7 0.2 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 ThiF family AdoHcyase_NAD PF00670.16 CDJ65360.1 - 0.099 12.4 0.4 0.31 10.8 0.1 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Bac_GDH PF05088.7 CDJ65360.1 - 0.21 8.9 0.2 0.3 8.4 0.1 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Josephin PF02099.12 CDJ65361.1 - 3.1e-47 160.1 0.0 5.4e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Josephin Peptidase_C12 PF01088.16 CDJ65361.1 - 0.0087 15.2 0.8 1 8.5 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase, family 1 UIM PF02809.15 CDJ65361.1 - 0.023 14.2 1.3 0.068 12.7 0.9 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF3619 PF12279.3 CDJ65363.1 - 0.04 13.9 1.1 0.064 13.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) TFIIA PF03153.8 CDJ65363.1 - 1.8 8.3 10.8 2.5 7.9 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3689 PF12463.3 CDJ65364.1 - 5e-30 104.3 0.2 1.5e-09 37.0 0.0 4.6 4 0 0 4 4 4 3 Protein of unknown function (DUF3689) SR-25 PF10500.4 CDJ65364.1 - 0.0013 18.2 15.5 0.0013 18.2 10.8 22.1 14 6 5 20 20 20 4 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CDJ65364.1 - 0.0018 18.5 13.2 0.0018 18.5 9.1 24.8 9 5 9 18 18 18 2 Cyclin-dependent kinase 2-associated protein Thioredoxin_8 PF13905.1 CDJ65366.1 - 0.038 14.0 0.0 40 4.4 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin-like Glutaredoxin PF00462.19 CDJ65366.1 - 0.52 10.3 1.9 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Glutaredoxin Myosin_head PF00063.16 CDJ65368.1 - 9.8e-25 86.6 0.1 1.4e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.7 CDJ65368.1 - 0.0035 16.4 0.1 0.0077 15.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CDJ65368.1 - 0.021 15.6 0.1 0.07 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CDJ65368.1 - 0.034 14.2 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CDJ65368.1 - 0.091 11.6 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Myosin_head PF00063.16 CDJ65369.1 - 1.5e-19 69.5 2.3 7.6e-15 54.0 0.2 2.9 4 0 0 4 4 4 2 Myosin head (motor domain) PGM_PMM_I PF02878.11 CDJ65370.1 - 1e-31 109.2 0.1 4e-31 107.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CDJ65370.1 - 1.3e-23 83.2 0.1 3.9e-23 81.7 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CDJ65370.1 - 3.5e-13 49.5 0.6 8.4e-13 48.3 0.4 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CDJ65370.1 - 0.0048 16.8 0.0 0.03 14.3 0.0 2.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1177 PF06675.6 CDJ65370.1 - 0.19 10.3 0.4 0.37 9.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) RVT_1 PF00078.22 CDJ65372.1 - 2.7e-10 39.9 0.0 6.4e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CDJ65372.1 - 1e-08 35.5 0.0 2.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ65372.1 - 1.7e-08 34.1 0.1 3.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ65372.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 CDJ65372.1 - 0.01 15.7 0.6 0.019 14.8 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.5 CDJ65372.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 CDJ65372.1 - 0.19 11.6 0.0 2.4 8.0 0.0 2.5 3 0 0 3 3 3 0 Retroviral aspartyl protease DUF4532 PF15046.1 CDJ65374.1 - 0.048 12.6 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) HSP90 PF00183.13 CDJ65376.1 - 6.3e-97 325.1 0.0 3.4e-59 200.6 0.2 4.1 3 1 0 3 3 3 3 Hsp90 protein HATPase_c_3 PF13589.1 CDJ65376.1 - 5.6e-10 39.0 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CDJ65376.1 - 5.2e-07 29.3 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_60s PF00428.14 CDJ65376.1 - 0.00043 20.6 5.8 0.00043 20.6 4.0 7.8 6 1 0 6 6 6 2 60s Acidic ribosomal protein MIase PF02426.11 CDJ65376.1 - 0.041 13.6 0.2 0.041 13.6 0.1 3.1 3 0 0 3 3 3 0 Muconolactone delta-isomerase Peptidase_U57 PF05582.7 CDJ65376.1 - 4.3 6.2 8.2 0.52 9.2 1.2 2.3 2 0 0 2 2 2 0 YabG peptidase U57 Peptidase_S28 PF05577.7 CDJ65377.1 - 1e-11 44.0 0.0 1.5e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Flg_hook PF02120.11 CDJ65377.1 - 0.32 10.7 0.1 0.32 10.7 0.1 1.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Raftlin PF15250.1 CDJ65378.1 - 0.017 13.6 23.8 0.022 13.3 16.5 1.0 1 0 0 1 1 1 0 Raftlin DUF3984 PF13136.1 CDJ65378.1 - 0.024 13.8 1.1 0.024 13.8 0.7 2.0 1 1 1 2 2 1 0 Protein of unknown function (DUF3984) CAF-1_p150 PF11600.3 CDJ65378.1 - 0.03 13.6 41.9 0.036 13.4 29.0 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 CDJ65378.1 - 0.067 13.0 26.5 0.086 12.7 18.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rtf2 PF04641.7 CDJ65378.1 - 0.069 12.3 28.8 0.084 12.0 20.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Adeno_hexon PF01065.14 CDJ65378.1 - 0.088 11.6 17.4 0.11 11.3 12.1 1.0 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain AUX_IAA PF02309.11 CDJ65378.1 - 0.12 12.1 25.4 0.14 11.8 17.6 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4045 PF13254.1 CDJ65378.1 - 0.12 11.5 22.8 0.14 11.3 15.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 CDJ65378.1 - 0.13 10.2 27.6 0.16 9.9 19.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.1 CDJ65378.1 - 0.2 11.9 26.6 0.24 11.7 18.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein GAGA_bind PF06217.7 CDJ65378.1 - 0.21 11.5 27.4 0.29 11.0 19.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Spore_coat_CotO PF14153.1 CDJ65378.1 - 0.27 10.6 38.0 0.31 10.4 26.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PAT1 PF09770.4 CDJ65378.1 - 0.3 9.2 56.4 0.34 9.1 39.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Parvo_coat PF00740.13 CDJ65378.1 - 0.31 9.9 23.6 0.39 9.6 16.3 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 TFIIA PF03153.8 CDJ65378.1 - 0.32 10.8 40.4 0.37 10.6 28.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YABBY PF04690.8 CDJ65378.1 - 0.35 11.0 17.2 0.43 10.8 11.9 1.2 1 0 0 1 1 1 0 YABBY protein VID27 PF08553.5 CDJ65378.1 - 0.37 8.9 17.5 0.41 8.8 12.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein FLO_LFY PF01698.11 CDJ65378.1 - 0.46 9.2 27.2 0.61 8.8 18.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PLRV_ORF5 PF01690.12 CDJ65378.1 - 0.48 9.5 22.0 0.53 9.3 15.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1510 PF07423.6 CDJ65378.1 - 0.5 9.6 33.8 0.62 9.3 23.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAGA-Tad1 PF12767.2 CDJ65378.1 - 0.51 9.9 29.2 0.58 9.7 20.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PPP4R2 PF09184.6 CDJ65378.1 - 0.56 9.7 19.8 0.69 9.4 13.7 1.1 1 0 0 1 1 1 0 PPP4R2 Gastrin PF00918.12 CDJ65378.1 - 0.7 10.7 27.3 1 10.1 18.9 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Med15 PF09606.5 CDJ65378.1 - 0.75 7.9 74.4 0.86 7.7 51.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Caldesmon PF02029.10 CDJ65378.1 - 0.85 7.9 27.9 1 7.6 19.3 1.0 1 0 0 1 1 1 0 Caldesmon Cellulose_synt PF03552.9 CDJ65378.1 - 0.87 7.8 10.7 0.99 7.6 7.4 1.2 1 0 0 1 1 1 0 Cellulose synthase Vfa1 PF08432.5 CDJ65378.1 - 0.9 9.5 31.8 1.2 9.1 22.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 CDJ65378.1 - 0.99 7.0 29.0 1.1 6.8 20.1 1.0 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDJ65378.1 - 1 6.9 28.1 1.1 6.8 19.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MRP-S31 PF15433.1 CDJ65378.1 - 1.2 8.5 30.6 1.5 8.1 21.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pneumo_phosprot PF02478.11 CDJ65378.1 - 1.3 8.5 10.1 1.4 8.3 7.0 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein DDRGK PF09756.4 CDJ65378.1 - 1.5 8.1 44.8 2.3 7.6 31.1 1.3 1 0 0 1 1 1 0 DDRGK domain AvrE PF11725.3 CDJ65378.1 - 1.8 5.4 26.8 2 5.3 18.6 1.0 1 0 0 1 1 1 0 Pathogenicity factor Pox_Ag35 PF03286.9 CDJ65378.1 - 1.8 8.0 25.6 2.4 7.6 17.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SUFU_C PF12470.3 CDJ65378.1 - 1.9 8.0 12.2 2.4 7.7 8.5 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain eIF-3_zeta PF05091.7 CDJ65378.1 - 1.9 6.9 34.1 2.9 6.4 23.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.17 CDJ65378.1 - 2.6 6.9 11.1 3.2 6.6 7.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_UL95 PF03038.9 CDJ65378.1 - 2.7 6.7 17.8 3.4 6.4 12.3 1.0 1 0 0 1 1 1 0 UL95 family Paramyxo_ncap PF00973.14 CDJ65378.1 - 2.9 6.4 22.4 3.2 6.3 15.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Herpes_env PF01673.13 CDJ65378.1 - 3.1 6.2 20.3 3.7 5.9 14.1 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein RNA_pol_Rpb1_5 PF04998.12 CDJ65378.1 - 3.2 6.9 17.2 3.9 6.6 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3450 PF11932.3 CDJ65378.1 - 3.7 6.7 41.2 4.6 6.4 28.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DHHW PF14286.1 CDJ65378.1 - 3.8 6.7 21.4 4.4 6.5 14.8 1.0 1 0 0 1 1 1 0 DHHW protein Neur_chan_memb PF02932.11 CDJ65378.1 - 3.9 7.2 22.0 4.8 7.0 15.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Atg14 PF10186.4 CDJ65378.1 - 4.1 6.2 38.4 5 5.9 26.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PA26 PF04636.8 CDJ65378.1 - 4.2 5.9 16.4 4.5 5.8 11.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) HGTP_anticodon2 PF12745.2 CDJ65378.1 - 4.3 6.4 24.0 5.3 6.1 16.7 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs FAM60A PF15396.1 CDJ65378.1 - 4.4 7.0 26.9 5.5 6.6 18.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDJ65378.1 - 4.7 6.9 28.0 8.3 6.1 19.4 1.4 1 0 0 1 1 1 0 DDHD domain Pox_RNA_Pol_19 PF05320.7 CDJ65378.1 - 4.8 6.8 16.8 6.4 6.5 11.7 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit MIP-T3 PF10243.4 CDJ65378.1 - 4.9 5.5 46.0 6.1 5.1 31.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 CDJ65378.1 - 5 6.4 31.4 7.1 5.9 21.7 1.3 1 0 0 1 1 1 0 Vta1 like DUF3810 PF12725.2 CDJ65378.1 - 5.5 5.7 12.9 6.9 5.4 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) eIF3_subunit PF08597.5 CDJ65378.1 - 5.7 6.4 34.7 9.1 5.7 24.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3807 PF12720.2 CDJ65378.1 - 5.9 7.0 37.5 8.1 6.5 26.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CPSF100_C PF13299.1 CDJ65378.1 - 6.1 7.0 25.4 11 6.2 17.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal UPF0565 PF10561.4 CDJ65378.1 - 6.2 5.6 15.1 8.2 5.2 10.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF1675 PF07897.6 CDJ65378.1 - 6.3 6.5 20.9 7.8 6.2 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2146 PF10220.4 CDJ65378.1 - 6.9 4.5 22.6 8.1 4.2 15.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SAPS PF04499.10 CDJ65378.1 - 7.3 5.1 24.9 8.4 4.8 17.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dicty_REP PF05086.7 CDJ65378.1 - 7.9 4.0 22.7 8.9 3.9 15.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tyrosinase PF00264.15 CDJ65378.1 - 8.1 6.5 14.8 9.8 6.2 10.3 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase SPX PF03105.14 CDJ65378.1 - 8.3 6.1 28.2 10 5.8 19.5 1.1 1 0 0 1 1 1 0 SPX domain DUF3446 PF11928.3 CDJ65379.1 - 0.02 15.0 20.7 0.11 12.7 3.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) BACK PF07707.10 CDJ65379.1 - 0.043 13.6 0.0 0.18 11.6 0.0 1.9 1 1 0 1 1 1 0 BTB And C-terminal Kelch NT5C PF06941.7 CDJ65379.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ETRAMP PF09716.5 CDJ65379.1 - 0.13 12.2 0.0 0.57 10.1 0.0 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CDK2AP PF09806.4 CDJ65379.1 - 1.4 9.1 9.4 5.7 7.1 3.8 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Pheromone PF08015.6 CDJ65379.1 - 7.8 7.4 14.0 9.5 7.1 4.0 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone PAN_1 PF00024.21 CDJ65380.1 - 4.9e-18 64.6 20.3 3.8e-07 29.7 1.8 3.3 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.1 CDJ65380.1 - 4.5e-14 51.8 21.8 8.1e-08 31.8 1.3 4.3 3 1 0 3 3 3 3 PAN domain PAN_2 PF08276.6 CDJ65380.1 - 0.0018 18.0 19.1 0.2 11.5 0.6 3.5 3 0 0 3 3 3 3 PAN-like domain KRAP_IP3R_bind PF14722.1 CDJ65380.1 - 0.0021 17.6 0.3 0.0021 17.6 0.2 1.9 2 0 0 2 2 2 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain PAN_3 PF08277.7 CDJ65380.1 - 0.027 14.0 0.2 0.027 14.0 0.2 3.2 3 0 0 3 3 3 0 PAN-like domain RAP1 PF07218.6 CDJ65381.1 - 9.1 4.2 17.3 9.9 4.1 12.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.14 CDJ65382.1 - 0.024 15.0 13.9 0.039 14.3 9.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pex14_N PF04695.8 CDJ65382.1 - 0.063 13.3 2.4 0.083 12.9 1.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 CDJ65382.1 - 0.093 12.0 2.9 0.096 12.0 2.0 1.1 1 0 0 1 1 1 0 Spt20 family Shadoo PF14999.1 CDJ65382.1 - 0.36 10.6 13.7 0.54 10.1 9.5 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective CDK2AP PF09806.4 CDJ65382.1 - 1.1 9.4 13.9 1.5 8.9 9.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Med15 PF09606.5 CDJ65382.1 - 1.3 7.1 22.7 1.7 6.7 15.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ATP_synt_I PF03899.10 CDJ65382.1 - 1.4 9.1 9.1 2.3 8.4 6.3 1.4 1 0 0 1 1 1 0 ATP synthase I chain ASFV_J13L PF05568.6 CDJ65382.1 - 1.8 8.0 8.9 2.4 7.6 6.2 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Nitroreductase PF00881.19 CDJ65382.1 - 4.8 6.9 8.1 8.3 6.2 5.6 1.4 1 1 0 1 1 1 0 Nitroreductase family Trypan_PARP PF05887.6 CDJ65383.1 - 4.6 7.0 20.6 0.93 9.3 8.0 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 CDJ65384.1 - 0.056 11.6 40.9 0.062 11.5 28.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ65384.1 - 0.072 12.9 30.4 0.081 12.8 21.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDJ65384.1 - 0.094 10.8 55.8 0.099 10.8 38.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 CDJ65384.1 - 0.13 11.5 36.2 0.16 11.2 25.1 1.1 1 0 0 1 1 1 0 SprA-related family SAGA-Tad1 PF12767.2 CDJ65384.1 - 0.16 11.6 23.4 0.19 11.3 16.2 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FLO_LFY PF01698.11 CDJ65384.1 - 0.3 9.8 14.3 0.36 9.6 9.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 CDJ65384.1 - 0.31 8.6 12.5 0.32 8.6 8.6 1.0 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 CDJ65384.1 - 0.36 10.5 12.3 0.45 10.2 8.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BNIP3 PF06553.7 CDJ65384.1 - 0.42 9.9 16.4 0.57 9.5 11.4 1.2 1 0 0 1 1 1 0 BNIP3 DDRGK PF09756.4 CDJ65384.1 - 0.56 9.5 28.0 0.73 9.2 19.4 1.1 1 0 0 1 1 1 0 DDRGK domain Hid1 PF12722.2 CDJ65384.1 - 0.7 7.4 14.7 0.74 7.4 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 CDJ65384.1 - 0.8 9.4 13.2 0.94 9.2 9.1 1.2 1 0 0 1 1 1 0 DDHD domain BTV_NS2 PF04514.7 CDJ65384.1 - 0.86 8.4 13.3 0.97 8.2 9.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Herpes_env PF01673.13 CDJ65384.1 - 2 6.8 8.9 2.1 6.7 6.2 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein RR_TM4-6 PF06459.7 CDJ65384.1 - 2.3 8.0 14.4 3 7.6 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.12 CDJ65384.1 - 2.3 6.9 10.2 2.5 6.8 7.1 1.0 1 0 0 1 1 1 0 Presenilin Exonuc_VII_L PF02601.10 CDJ65384.1 - 2.9 7.0 14.1 3.4 6.7 9.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF605 PF04652.11 CDJ65384.1 - 3.2 7.0 24.3 3.6 6.9 16.9 1.1 1 0 0 1 1 1 0 Vta1 like MMR1 PF08505.5 CDJ65384.1 - 3.3 7.6 20.2 3.7 7.5 14.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein HemX PF04375.9 CDJ65384.1 - 3.8 6.0 32.2 4.3 5.8 22.3 1.0 1 0 0 1 1 1 0 HemX FNIP_N PF14636.1 CDJ65384.1 - 3.8 7.9 17.4 5.9 7.3 12.1 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Peptidase_S15 PF02129.13 CDJ65384.1 - 4.1 6.7 14.4 5.4 6.3 9.9 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Band_3_cyto PF07565.8 CDJ65384.1 - 4.3 6.7 14.8 5.9 6.3 10.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spore_coat_CotO PF14153.1 CDJ65384.1 - 4.3 6.7 23.8 5.3 6.4 16.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO AUX_IAA PF02309.11 CDJ65384.1 - 4.4 6.9 16.3 5.7 6.6 11.3 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4407 PF14362.1 CDJ65384.1 - 5 5.9 22.4 6.4 5.6 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.3 CDJ65384.1 - 5.2 5.6 16.2 6.3 5.4 11.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.11 CDJ65384.1 - 6 6.6 11.9 7.6 6.3 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HlyD_2 PF12700.2 CDJ65384.1 - 6.2 5.8 14.1 7.3 5.6 9.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein eIF3_subunit PF08597.5 CDJ65384.1 - 6.7 6.1 17.2 8.5 5.8 11.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1675 PF07897.6 CDJ65384.1 - 9.6 5.9 12.9 11 5.7 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FAM195 PF14799.1 CDJ65385.1 - 0.045 13.6 1.5 0.073 12.9 1.0 1.2 1 0 0 1 1 1 0 FAM195 family Sporozoite_P67 PF05642.6 CDJ65386.1 - 0.016 13.1 4.9 0.024 12.4 3.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.4 CDJ65386.1 - 0.14 11.6 11.0 0.19 11.1 7.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ65386.1 - 1.5 8.9 13.2 2.4 8.2 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) YebO PF13974.1 CDJ65387.1 - 0.18 11.5 9.2 0.13 12.0 3.7 2.5 3 0 0 3 3 3 0 YebO-like protein Pex14_N PF04695.8 CDJ65387.1 - 2.5 8.1 26.9 0.59 10.1 5.4 2.5 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1675 PF07897.6 CDJ65387.1 - 4.4 7.0 16.4 0.6 9.9 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Ribosomal_60s PF00428.14 CDJ65388.1 - 0.025 14.9 4.9 0.064 13.6 3.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Abi PF02517.11 CDJ65391.1 - 3e-08 33.7 16.6 4.6e-07 29.8 8.0 4.7 2 2 0 2 2 2 1 CAAX protease self-immunity CopD PF05425.8 CDJ65392.1 - 0.0026 17.9 0.3 0.0026 17.9 0.2 2.2 3 0 0 3 3 3 1 Copper resistance protein D Pro_racemase PF05544.6 CDJ65393.1 - 1.5 7.5 5.8 1.8 7.3 4.0 1.2 1 0 0 1 1 1 0 Proline racemase DUF2981 PF11200.3 CDJ65393.1 - 4.8 6.1 10.7 5.8 5.9 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF572 PF04502.8 CDJ65393.1 - 8.1 5.5 42.1 10 5.2 29.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DnaJ PF00226.26 CDJ65394.1 - 0.0067 16.1 1.4 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain EF-hand_1 PF00036.27 CDJ65397.1 - 9.5e-06 24.5 0.0 0.033 13.4 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CDJ65397.1 - 0.00032 20.7 0.0 0.0023 18.0 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CDJ65397.1 - 0.0011 18.7 0.1 0.64 10.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CDJ65397.1 - 0.0014 18.1 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CDJ65397.1 - 0.032 13.5 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.1 CDJ65397.1 - 0.35 10.5 1.4 60 3.4 0.1 3.1 3 0 0 3 3 3 0 EF hand SR-25 PF10500.4 CDJ65397.1 - 5.2 6.4 31.9 2.9 7.3 7.9 4.2 3 1 0 4 4 4 0 Nuclear RNA-splicing-associated protein Glyco_hydro_19 PF00182.14 CDJ65398.1 - 1.1e-08 35.0 0.2 2.8e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Chitinase class I Suf PF05843.9 CDJ65398.1 - 0.89 9.2 2.7 1.8 8.2 1.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Shisa PF13908.1 CDJ65398.1 - 5.6 7.0 10.1 15 5.6 7.0 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PUL PF08324.6 CDJ65399.1 - 4.1e-25 88.0 1.6 4.1e-25 88.0 1.1 1.5 2 0 0 2 2 1 1 PUL domain PFU PF09070.6 CDJ65399.1 - 1.3e-23 83.2 0.0 4.6e-23 81.4 0.0 1.9 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CDJ65399.1 - 1.5e-15 56.3 15.0 1.3e-05 24.8 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3357 PF11837.3 CDJ65399.1 - 3.3e-05 23.7 3.6 0.17 11.7 0.8 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF3357) Spt20 PF12090.3 CDJ65399.1 - 0.00085 18.7 1.8 0.038 13.3 0.1 2.5 2 0 0 2 2 2 1 Spt20 family Trypan_glycop_C PF10659.4 CDJ65399.1 - 0.15 12.3 6.3 0.074 13.3 0.9 2.8 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain RAB3GAP2_N PF14655.1 CDJ65399.1 - 0.43 9.5 12.0 1.1 8.2 4.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDJ65399.1 - 0.67 9.6 12.3 0.058 13.1 2.6 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3373 PF11853.3 CDJ65399.1 - 3.6 6.0 8.7 6.6 5.1 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Ribosomal_60s PF00428.14 CDJ65399.1 - 5.1 7.5 46.1 0.11 12.8 9.8 4.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein G0-G1_switch_2 PF15103.1 CDJ65399.1 - 6.6 7.0 9.2 84 3.4 0.0 2.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 FHIPEP PF00771.15 CDJ65399.1 - 8 4.6 8.4 2.7 6.1 2.5 2.3 3 0 0 3 3 3 0 FHIPEP family Pex14_N PF04695.8 CDJ65399.1 - 9.2 6.3 24.1 1.2 9.1 4.7 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDJ65401.1 - 0.15 10.2 42.8 0.36 8.9 4.4 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1466 PF07326.6 CDJ65402.1 - 0.013 14.8 0.1 0.013 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1466) DUF4315 PF14193.1 CDJ65403.1 - 0.0056 16.5 2.0 0.0056 16.5 1.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4315) IncA PF04156.9 CDJ65403.1 - 0.15 11.6 2.3 0.33 10.5 1.6 1.5 1 0 0 1 1 1 0 IncA protein DUF2968 PF11180.3 CDJ65403.1 - 0.22 10.8 11.3 0.011 15.0 3.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF4094 PF13334.1 CDJ65403.1 - 3.9 7.9 6.9 1.4 9.3 1.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) UCR_UQCRX_QCR9 PF05365.7 CDJ65404.1 - 0.46 10.1 2.1 0.92 9.1 0.8 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like KASH PF10541.4 CDJ65404.1 - 0.55 10.1 5.6 0.24 11.2 1.7 1.9 2 0 0 2 2 2 0 Nuclear envelope localisation domain Collagen PF01391.13 CDJ65405.1 - 0.00014 21.3 44.0 0.00014 21.3 30.5 3.7 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) DUF4630 PF15443.1 CDJ65406.1 - 5 6.9 7.4 5.2 6.8 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) PAT1 PF09770.4 CDJ65407.1 - 0.011 13.9 47.1 0.013 13.7 32.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ65407.1 - 0.022 12.9 46.9 0.023 12.9 32.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 CDJ65407.1 - 0.069 12.5 26.6 0.08 12.3 18.5 1.2 1 0 0 1 1 1 0 Vta1 like THRAP3_BCLAF1 PF15440.1 CDJ65407.1 - 0.18 10.3 21.7 0.22 10.1 15.0 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family TFIIA PF03153.8 CDJ65407.1 - 0.26 11.1 33.4 0.33 10.7 23.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 CDJ65407.1 - 0.42 9.9 24.2 0.56 9.5 16.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TmoB PF06234.7 CDJ65407.1 - 4 7.3 5.4 8 6.4 0.3 2.4 2 1 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Presenilin PF01080.12 CDJ65407.1 - 4.2 6.0 9.6 5.3 5.7 6.6 1.1 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.8 CDJ65408.1 - 9e-28 96.8 0.2 1.1e-27 96.5 0.2 1.0 1 0 0 1 1 1 1 Utp14 protein CW_binding_2 PF04122.7 CDJ65408.1 - 0.058 13.6 1.5 0.1 12.8 1.0 1.4 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 RepA1_leader PF08048.7 CDJ65408.1 - 0.13 12.3 4.3 0.29 11.2 3.0 1.6 1 0 0 1 1 1 0 Tap RepA1 leader peptide KASH PF10541.4 CDJ65408.1 - 1.2 9.0 12.1 0.19 11.5 4.3 2.2 1 1 1 2 2 2 0 Nuclear envelope localisation domain Ribosomal_60s PF00428.14 CDJ65408.1 - 3.5 8.1 11.5 9.4 6.7 7.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fip1 PF05182.8 CDJ65409.1 - 1.4e-05 24.2 0.1 3.5e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Fip1 motif Herpes_UL87 PF03043.9 CDJ65409.1 - 6.3 5.0 11.0 7.7 4.7 7.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF3617 PF12276.3 CDJ65410.1 - 0.00048 19.6 15.5 0.00072 19.0 10.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3617) Shadoo PF14999.1 CDJ65410.1 - 0.00055 19.8 4.8 0.00081 19.2 3.3 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective HemX PF04375.9 CDJ65410.1 - 0.0018 16.9 14.9 0.0019 16.8 10.3 1.1 1 0 0 1 1 1 1 HemX Med15 PF09606.5 CDJ65410.1 - 0.016 13.4 30.2 0.016 13.4 21.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2232 PF09991.4 CDJ65410.1 - 0.023 13.6 1.0 0.028 13.4 0.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ctr PF04145.10 CDJ65410.1 - 0.041 13.9 3.0 0.051 13.6 2.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF1104 PF06518.6 CDJ65410.1 - 0.061 13.4 2.0 0.094 12.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) FHIPEP PF00771.15 CDJ65410.1 - 0.062 11.6 2.4 0.069 11.4 1.6 1.0 1 0 0 1 1 1 0 FHIPEP family Glyco_hydro_85 PF03644.8 CDJ65410.1 - 0.068 12.2 5.1 0.072 12.2 3.5 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 DUF4557 PF15101.1 CDJ65410.1 - 0.14 11.9 14.6 0.16 11.8 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4367 PF14285.1 CDJ65410.1 - 0.15 11.3 0.3 0.22 10.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) MMR1 PF08505.5 CDJ65410.1 - 0.16 11.9 14.6 0.19 11.7 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Ribosomal_60s PF00428.14 CDJ65410.1 - 0.18 12.2 18.7 0.068 13.5 10.9 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Suf PF05843.9 CDJ65410.1 - 0.19 11.4 10.8 0.19 11.4 7.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ65410.1 - 0.19 11.0 7.6 0.21 10.9 5.3 1.2 1 0 0 1 1 1 0 Spt20 family Serinc PF03348.10 CDJ65410.1 - 0.26 9.9 4.8 0.26 9.9 3.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Oleosin PF01277.12 CDJ65410.1 - 0.39 10.3 2.6 0.55 9.8 1.8 1.2 1 0 0 1 1 1 0 Oleosin FimP PF09766.4 CDJ65410.1 - 0.43 9.5 13.2 0.5 9.3 9.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF2512 PF10710.4 CDJ65410.1 - 0.69 9.3 2.6 0.96 8.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) DUF2215 PF10225.4 CDJ65410.1 - 0.85 9.0 3.8 0.95 8.8 2.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Adeno_hexon PF01065.14 CDJ65410.1 - 1.3 7.7 9.7 1.5 7.5 6.7 1.0 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Gastrin PF00918.12 CDJ65410.1 - 1.4 9.7 16.4 1.9 9.3 11.4 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Hid1 PF12722.2 CDJ65410.1 - 1.5 6.4 7.2 1.3 6.5 5.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM247 PF15444.1 CDJ65410.1 - 1.6 8.4 6.3 1.9 8.2 4.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 ADP_PFK_GK PF04587.10 CDJ65410.1 - 1.9 6.6 5.0 2.3 6.3 3.5 1.0 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region R_equi_Vir PF05526.6 CDJ65410.1 - 2.9 7.5 9.7 4 7.0 6.7 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Band_3_cyto PF07565.8 CDJ65410.1 - 3.3 7.1 7.8 3.8 6.9 5.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3373 PF11853.3 CDJ65410.1 - 4.5 5.7 8.3 5 5.5 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TFIIA PF03153.8 CDJ65410.1 - 4.8 6.9 26.1 5 6.9 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RED_N PF07808.8 CDJ65410.1 - 6.2 5.9 15.1 8.8 5.4 10.5 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region RskA PF10099.4 CDJ65410.1 - 8.7 6.0 23.2 14 5.3 16.0 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Neur_chan_memb PF02932.11 CDJ65410.1 - 9 6.1 6.0 8.7 6.1 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cyclin_C PF02984.14 CDJ65412.1 - 0.013 15.4 0.4 0.025 14.5 0.3 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain TRAM_LAG1_CLN8 PF03798.11 CDJ65412.1 - 0.23 11.0 1.5 0.26 10.8 0.2 1.7 1 1 1 2 2 2 0 TLC domain PLAC8 PF04749.12 CDJ65412.1 - 5.7 7.5 17.8 0.23 12.0 4.8 2.5 1 1 2 3 3 3 0 PLAC8 family Glucos_trans_II PF14264.1 CDJ65412.1 - 5.8 5.8 10.5 0.85 8.5 1.3 2.7 3 0 0 3 3 3 0 Glucosyl transferase GtrII GRASP55_65 PF04495.9 CDJ65414.1 - 1.1e-08 35.0 0.0 2.1e-08 34.2 0.0 1.4 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain SAPS PF04499.10 CDJ65415.1 - 0.00085 18.0 3.3 0.0015 17.2 2.3 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Ribosomal_L36e PF01158.13 CDJ65417.1 - 5.3e-38 128.9 5.6 6.2e-38 128.7 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e CLTH PF10607.4 CDJ65417.1 - 0.13 11.9 0.1 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain SUI1 PF01253.17 CDJ65417.1 - 1.5 8.6 4.1 21 5.0 2.9 2.3 1 1 0 1 1 1 0 Translation initiation factor SUI1 Bystin PF05291.6 CDJ65418.1 - 1.2e-109 365.8 2.1 1.7e-109 365.4 1.4 1.1 1 0 0 1 1 1 1 Bystin NT-C2 PF10358.4 CDJ65418.1 - 0.097 12.1 0.1 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2693 PF10902.3 CDJ65418.1 - 0.14 12.0 0.3 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2693) rve PF00665.21 CDJ65420.1 - 0.0022 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ65420.1 - 0.092 12.2 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Integrase core domain DUF2361 PF10153.4 CDJ65423.1 - 4.6 7.4 35.1 0.53 10.4 3.0 3.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2361) Ribosomal_60s PF00428.14 CDJ65423.1 - 6.2 7.3 13.0 2.1 8.8 6.3 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein CAP PF00188.21 CDJ65425.1 - 0.014 15.9 0.1 0.02 15.3 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich secretory protein family WD40 PF00400.27 CDJ65426.1 - 2.5e-25 87.3 23.9 6.4e-07 29.0 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CDJ65426.1 - 0.0026 16.0 0.2 0.14 10.2 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 QCR10 PF09796.4 CDJ65427.1 - 0.034 13.7 0.0 0.34 10.6 0.0 2.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) PapD-like PF14874.1 CDJ65429.1 - 0.0001 22.1 0.4 0.26 11.2 0.0 3.7 3 1 0 3 3 3 2 Flagellar-associated PapD-like Vps26 PF03643.10 CDJ65432.1 - 1.5e-106 355.2 1.3 1.7e-106 355.0 0.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CDJ65432.1 - 0.00053 19.8 2.8 0.43 10.3 0.3 3.4 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CAP PF00188.21 CDJ65434.1 - 2e-13 50.8 0.4 2e-13 50.8 0.2 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family ELH PF02323.10 CDJ65434.1 - 0.0013 17.9 0.1 0.0017 17.5 0.1 1.1 1 0 0 1 1 1 1 Egg-laying hormone precursor Surface_antigen PF11054.3 CDJ65434.1 - 0.034 13.5 0.2 0.034 13.5 0.1 2.9 1 1 1 3 3 3 0 Sporozoite TA4 surface antigen PTS_2-RNA PF01885.11 CDJ65435.1 - 1.4e-09 37.4 0.0 1.3e-08 34.3 0.0 2.2 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ycf1 PF05758.7 CDJ65435.1 - 2.3 5.8 21.6 3.9 5.0 14.3 1.6 2 0 0 2 2 2 0 Ycf1 PCI PF01399.22 CDJ65436.1 - 2.2e-12 47.1 0.6 4e-12 46.3 0.5 1.4 1 0 0 1 1 1 1 PCI domain Serglycin PF04360.7 CDJ65436.1 - 3.6 7.3 5.2 0.47 10.1 0.3 1.8 2 0 0 2 2 2 0 Serglycin TPR_7 PF13176.1 CDJ65436.1 - 5.5 7.0 13.1 3.1 7.7 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat Pex14_N PF04695.8 CDJ65437.1 - 0.0011 19.0 2.5 0.0011 18.9 1.7 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region OmpH PF03938.9 CDJ65437.1 - 0.0035 17.2 20.1 0.0044 16.9 14.0 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Afaf PF15339.1 CDJ65437.1 - 0.0051 16.4 0.2 0.0065 16.0 0.2 1.1 1 0 0 1 1 1 1 Acrosome formation-associated factor BAF1_ABF1 PF04684.8 CDJ65437.1 - 0.009 14.9 14.9 0.0093 14.8 10.3 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDJ65437.1 - 0.021 13.0 23.0 0.02 13.0 16.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Topoisom_I_N PF02919.10 CDJ65437.1 - 0.021 14.0 0.4 0.022 14.0 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Suf PF05843.9 CDJ65437.1 - 0.032 13.9 7.6 0.035 13.8 5.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDC45 PF02724.9 CDJ65437.1 - 0.036 12.0 2.7 0.037 12.0 1.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Mis12 PF05859.7 CDJ65437.1 - 0.06 13.1 5.2 0.085 12.6 3.6 1.3 1 0 0 1 1 1 0 Mis12 protein DUF4175 PF13779.1 CDJ65437.1 - 0.07 10.8 22.3 0.084 10.5 15.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.4 CDJ65437.1 - 0.075 11.2 10.4 0.078 11.2 7.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 IncA PF04156.9 CDJ65437.1 - 0.089 12.3 11.2 0.091 12.3 7.8 1.2 1 0 0 1 1 1 0 IncA protein FimP PF09766.4 CDJ65437.1 - 0.095 11.7 12.0 0.12 11.4 8.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF4192 PF13830.1 CDJ65437.1 - 0.11 12.0 2.4 0.12 11.9 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) EIIBC-GUT_N PF03612.9 CDJ65437.1 - 0.12 12.0 3.0 0.14 11.7 2.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Endonuc_Holl PF10107.4 CDJ65437.1 - 0.12 12.0 5.3 0.15 11.7 3.7 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase VirC2 PF07181.6 CDJ65437.1 - 0.12 11.7 1.7 0.13 11.6 1.2 1.2 1 0 0 1 1 1 0 VirC2 protein GvpL_GvpF PF06386.6 CDJ65437.1 - 0.13 11.7 5.3 0.15 11.6 3.6 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Kei1 PF08552.6 CDJ65437.1 - 0.15 11.7 0.8 0.14 11.7 0.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SpaB_C PF14028.1 CDJ65437.1 - 0.16 11.4 4.5 0.19 11.2 3.1 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain DUF4557 PF15101.1 CDJ65437.1 - 0.18 11.6 13.2 0.23 11.2 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Herpes_ori_bp PF02399.10 CDJ65437.1 - 0.2 9.5 2.0 0.25 9.2 1.4 1.1 1 0 0 1 1 1 0 Origin of replication binding protein PAT1 PF09770.4 CDJ65437.1 - 0.22 9.7 17.0 0.22 9.7 11.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Raptor_N PF14538.1 CDJ65437.1 - 0.26 11.1 3.7 0.31 10.8 2.6 1.1 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Spt20 PF12090.3 CDJ65437.1 - 0.31 10.3 6.7 0.37 10.1 4.6 1.2 1 0 0 1 1 1 0 Spt20 family Folate_carrier PF01770.13 CDJ65437.1 - 0.37 9.2 2.8 0.41 9.1 1.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier ATHILA PF03078.10 CDJ65437.1 - 0.42 9.1 3.8 0.47 8.9 2.6 1.0 1 0 0 1 1 1 0 ATHILA ORF-1 family DUF3371 PF11851.3 CDJ65437.1 - 0.43 11.2 11.8 0.56 10.8 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) RR_TM4-6 PF06459.7 CDJ65437.1 - 0.45 10.3 7.8 0.63 9.8 5.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OATP PF03137.15 CDJ65437.1 - 0.51 8.3 2.1 0.57 8.1 1.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family IGPS PF00218.16 CDJ65437.1 - 0.54 9.2 5.4 0.67 8.9 3.7 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase ZYG-11_interact PF05884.7 CDJ65437.1 - 0.67 8.9 3.9 0.7 8.9 2.7 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Pex26 PF07163.7 CDJ65437.1 - 0.7 8.7 5.3 0.82 8.5 3.7 1.1 1 0 0 1 1 1 0 Pex26 protein RED_N PF07808.8 CDJ65437.1 - 1 8.5 10.8 1.2 8.3 7.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF4199 PF13858.1 CDJ65437.1 - 1 9.2 3.5 1.3 8.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Serinc PF03348.10 CDJ65437.1 - 1.7 7.2 5.1 2.1 6.9 3.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4407 PF14362.1 CDJ65437.1 - 1.9 7.3 9.9 2.3 7.1 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 CDJ65437.1 - 3.9 5.6 10.8 4.4 5.4 7.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3373 PF11853.3 CDJ65437.1 - 4.2 5.7 6.6 4.6 5.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DivIC PF04977.10 CDJ65437.1 - 5.4 6.5 17.4 8.6 5.9 12.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Ycf1 PF05758.7 CDJ65438.1 - 0.054 11.2 1.6 0.044 11.5 1.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF4175 PF13779.1 CDJ65438.1 - 0.095 10.3 26.0 0.11 10.1 18.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PLRV_ORF5 PF01690.12 CDJ65438.1 - 0.11 11.6 11.8 0.12 11.5 8.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein HlyD_2 PF12700.2 CDJ65438.1 - 0.19 10.8 4.6 0.22 10.6 3.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Draxin PF15550.1 CDJ65438.1 - 0.22 11.1 5.5 0.26 10.8 3.8 1.2 1 0 0 1 1 1 0 Draxin 2OG-FeII_Oxy_2 PF13532.1 CDJ65438.1 - 1.7 8.4 7.9 2.9 7.6 5.4 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3584 PF12128.3 CDJ65438.1 - 1.9 5.6 21.9 2.6 5.2 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AvrE PF11725.3 CDJ65438.1 - 2.8 4.8 20.0 2.6 4.9 13.9 1.1 1 0 0 1 1 1 0 Pathogenicity factor TMPIT PF07851.8 CDJ65438.1 - 3.1 6.7 11.7 3.8 6.4 8.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.10 CDJ65438.1 - 3.2 6.8 10.0 0.57 9.3 4.4 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pol_alpha_B_N PF08418.5 CDJ65438.1 - 3.3 7.1 17.2 2.4 7.6 11.1 1.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Mcm10 PF09332.6 CDJ65438.1 - 3.4 6.9 16.5 4.5 6.5 11.4 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF1395 PF07160.7 CDJ65438.1 - 4.3 6.7 13.3 5.9 6.3 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) TFIIA PF03153.8 CDJ65438.1 - 5.1 6.8 37.0 5.4 6.8 25.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDJ65438.1 - 5.4 6.8 5.7 6.5 6.5 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3365 PF11845.3 CDJ65438.1 - 6 6.6 11.7 8.6 6.1 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) Hid1 PF12722.2 CDJ65438.1 - 7.2 4.1 10.6 8.2 3.9 7.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FemAB PF02388.11 CDJ65438.1 - 7.3 5.1 13.4 9 4.8 9.3 1.1 1 0 0 1 1 1 0 FemAB family Cadherin_C PF01049.12 CDJ65438.1 - 7.8 6.5 10.8 18 5.3 7.5 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic region DUF2393 PF09624.5 CDJ65438.1 - 8 5.9 8.6 10 5.6 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) UPF0560 PF10577.4 CDJ65438.1 - 8.5 4.4 12.8 8.3 4.5 8.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 V-ATPase_H_C PF11698.3 CDJ65440.1 - 2.8e-31 107.8 1.0 1.2e-30 105.8 0.2 2.2 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 CDJ65440.1 - 2.4e-21 76.1 0.0 5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H IncA PF04156.9 CDJ65440.1 - 2.1e-06 27.4 2.5 2.1e-06 27.4 1.7 1.7 1 1 0 1 1 1 1 IncA protein Suf PF05843.9 CDJ65440.1 - 0.013 15.2 8.6 0.023 14.4 6.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ65440.1 - 0.025 12.8 34.1 0.034 12.3 23.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDJ65440.1 - 0.053 13.5 16.0 0.11 12.5 11.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.11 CDJ65440.1 - 0.063 13.1 2.1 0.086 12.7 1.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 CDJ65440.1 - 0.13 11.2 1.6 0.2 10.6 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 CDJ65440.1 - 0.13 10.4 32.1 0.17 10.1 22.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDJ65440.1 - 0.25 11.1 14.0 0.51 10.1 9.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 CDJ65440.1 - 0.3 8.7 9.3 0.47 8.0 6.5 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDRGK PF09756.4 CDJ65440.1 - 0.49 9.7 12.9 0.79 9.1 9.0 1.3 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.7 CDJ65440.1 - 0.6 9.9 6.8 0.9 9.3 4.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF966 PF06136.8 CDJ65440.1 - 0.75 9.1 12.0 1.1 8.5 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Menin PF05053.8 CDJ65440.1 - 0.82 7.7 11.4 1.2 7.2 7.9 1.2 1 0 0 1 1 1 0 Menin Gag_spuma PF03276.9 CDJ65440.1 - 1.1 7.5 25.2 1.6 6.9 17.5 1.2 1 0 0 1 1 1 0 Spumavirus gag protein eIF-3_zeta PF05091.7 CDJ65440.1 - 1.5 7.3 15.5 2.3 6.7 10.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIH1 PF08190.7 CDJ65440.1 - 1.6 8.1 19.8 2.3 7.5 13.7 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 TFIIA PF03153.8 CDJ65440.1 - 1.7 8.4 26.9 2.5 7.8 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BORG_CEP PF14957.1 CDJ65440.1 - 2.1 9.3 8.8 2.4 9.0 5.4 1.5 1 1 0 1 1 1 0 Cdc42 effector Serinc PF03348.10 CDJ65440.1 - 3 6.4 6.9 4.7 5.8 4.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DOR PF14839.1 CDJ65440.1 - 5.4 6.6 19.2 11 5.7 13.3 1.5 1 0 0 1 1 1 0 DOR family DUF4484 PF14831.1 CDJ65441.1 - 0.018 15.1 0.2 0.018 15.1 0.1 6.3 8 0 0 8 8 8 0 Domain of unknown function (DUF4484) Med15 PF09606.5 CDJ65442.1 - 0.00079 17.7 82.9 0.00079 17.7 57.5 4.8 3 2 1 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal Mem_trans PF03547.13 CDJ65442.1 - 0.085 11.1 1.5 0.16 10.2 1.1 1.4 1 0 0 1 1 1 0 Membrane transport protein Ycf1 PF05758.7 CDJ65442.1 - 5.4 4.5 20.0 9.4 3.7 13.9 1.4 1 0 0 1 1 1 0 Ycf1 CDK2AP PF09806.4 CDJ65443.1 - 0.0088 16.2 4.5 0.01 16.0 3.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein DUF3357 PF11837.3 CDJ65443.1 - 0.01 15.6 2.6 0.015 15.1 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Chorion_2 PF03964.10 CDJ65443.1 - 0.023 15.2 3.5 0.031 14.8 2.4 1.3 1 0 0 1 1 1 0 Chorion family 2 DUF3984 PF13136.1 CDJ65443.1 - 0.04 13.1 6.0 0.047 12.9 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) SoxE PF06525.6 CDJ65443.1 - 0.065 12.5 0.3 0.071 12.3 0.2 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Sporozoite_P67 PF05642.6 CDJ65443.1 - 0.077 10.8 1.7 0.081 10.7 1.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CD34_antigen PF06365.7 CDJ65443.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family FxsA PF04186.8 CDJ65443.1 - 0.13 11.9 1.3 0.18 11.4 0.9 1.2 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein DUF3693 PF12472.3 CDJ65443.1 - 0.14 11.8 0.4 0.3 10.7 0.2 1.7 2 0 0 2 2 2 0 Phage related protein UPF0233 PF06781.7 CDJ65443.1 - 0.18 11.4 0.2 0.36 10.4 0.0 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) Apt1 PF10351.4 CDJ65443.1 - 0.34 9.7 2.4 0.45 9.3 1.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1675 PF07897.6 CDJ65444.1 - 0.1 12.4 6.2 0.13 12.1 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PGA2 PF07543.7 CDJ65444.1 - 0.13 12.0 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4131 PF13567.1 CDJ65444.1 - 5.3 6.4 8.3 4.1 6.7 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3446 PF11928.3 CDJ65445.1 - 1.4 9.1 23.4 3 8.0 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) TauE PF01925.14 CDJ65445.1 - 2 7.7 12.7 1.4e+02 1.8 2.5 2.2 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF2752 PF10825.3 CDJ65446.1 - 0.14 12.2 2.9 0.086 12.8 0.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2752) ACP_syn_III PF08545.5 CDJ65448.1 - 4.6e-24 83.8 4.7 8.2e-24 83.0 0.8 3.0 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 CDJ65448.1 - 2.5e-21 75.4 0.1 1.3e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Abhydrolase_5 PF12695.2 CDJ65448.1 - 0.0045 16.7 0.2 0.01 15.6 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chal_sti_synt_C PF02797.10 CDJ65448.1 - 0.011 15.6 0.0 0.038 13.9 0.0 1.7 1 1 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Ribosomal_60s PF00428.14 CDJ65448.1 - 0.018 15.3 5.9 0.018 15.3 4.1 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein HrpB1_HrpK PF09613.5 CDJ65449.1 - 0.16 11.4 1.0 0.2 11.1 0.7 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Clat_adaptor_s PF01217.15 CDJ65450.1 - 0.00011 21.8 0.4 0.00017 21.3 0.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 CDJ65451.1 - 4.4e-37 127.6 0.0 4e-32 111.3 0.0 2.0 1 1 1 2 2 2 2 Adaptor complexes medium subunit family BatD PF13584.1 CDJ65452.1 - 0.061 11.9 0.3 0.084 11.4 0.2 1.2 1 0 0 1 1 1 0 Oxygen tolerance OmpH PF03938.9 CDJ65452.1 - 2.4 8.0 18.8 4.8 7.1 13.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4242 PF14026.1 CDJ65453.1 - 3 7.9 4.6 5.7 7.1 1.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4242) Spt20 PF12090.3 CDJ65454.1 - 0.67 9.2 3.4 1.1 8.6 2.4 1.3 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.14 CDJ65455.1 - 0.015 15.6 24.7 0.015 15.6 17.1 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein Pkinase PF00069.20 CDJ65456.1 - 1e-45 155.9 0.0 1.2e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65456.1 - 1.2e-20 73.6 0.0 1.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ65456.1 - 0.00012 21.1 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDJ65456.1 - 0.017 14.2 0.0 0.05 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RskA PF10099.4 CDJ65459.1 - 0.14 11.8 1.5 0.14 11.8 1.0 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SR-25 PF10500.4 CDJ65459.1 - 1.9 7.9 11.5 1.8 7.9 8.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ65459.1 - 8.7 6.4 12.6 9.6 6.2 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.14 CDJ65460.1 - 0.98 9.8 12.7 0.21 12.0 6.3 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAT PF03417.11 CDJ65460.1 - 1.1 8.6 12.0 1.2 8.4 8.3 1.0 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase R_equi_Vir PF05526.6 CDJ65460.1 - 1.7 8.2 8.0 2.2 7.9 5.5 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein vMSA PF00695.14 CDJ65460.1 - 1.7 7.7 10.3 1.8 7.6 7.2 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF2217 PF10265.4 CDJ65460.1 - 2.4 6.8 15.7 2.7 6.6 10.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4175 PF13779.1 CDJ65460.1 - 3.4 5.2 33.5 3.5 5.2 23.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDK5_activator PF03261.10 CDJ65460.1 - 4.2 6.5 19.8 4.4 6.5 13.7 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Zip PF02535.17 CDJ65460.1 - 7.1 5.5 6.2 8.1 5.3 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SprA-related PF12118.3 CDJ65460.1 - 7.2 5.8 36.5 8 5.6 25.3 1.2 1 0 0 1 1 1 0 SprA-related family Gag_spuma PF03276.9 CDJ65460.1 - 7.3 4.7 28.4 8.2 4.6 19.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein TFIIA PF03153.8 CDJ65460.1 - 8 6.2 28.3 8.8 6.1 19.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ65460.1 - 9.7 4.2 29.9 9.9 4.2 20.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GpcrRhopsn4 PF10192.4 CDJ65461.1 - 1.3e-07 31.0 1.1 1.7e-07 30.6 0.8 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 CDJ65461.1 - 9.1e-05 21.5 1.0 0.00012 21.1 0.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3038 PF11237.3 CDJ65463.1 - 0.054 13.2 0.3 0.054 13.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) AAA_22 PF13401.1 CDJ65463.1 - 0.17 11.9 0.9 2.3 8.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain Mt_ATP-synt_B PF05405.9 CDJ65463.1 - 4.6 6.6 7.6 2.2 7.7 1.3 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FliT PF05400.8 CDJ65463.1 - 6.3 7.2 12.3 16 6.0 0.2 2.4 2 1 0 2 2 2 0 Flagellar protein FliT Spt20 PF12090.3 CDJ65464.1 - 0.056 12.7 0.1 0.056 12.7 0.0 5.3 4 1 1 5 5 5 0 Spt20 family Suf PF05843.9 CDJ65464.1 - 6 6.5 47.2 0.051 13.3 0.4 4.4 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) DUF4614 PF15391.1 CDJ65465.1 - 0.041 13.6 14.6 0.051 13.3 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Pex14_N PF04695.8 CDJ65465.1 - 9.3 6.2 14.3 17 5.4 9.9 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cation_ATPase_C PF00689.16 CDJ65466.1 - 5.3e-08 32.5 4.5 2.2e-07 30.6 0.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDJ65466.1 - 0.0001 22.8 4.4 0.00025 21.5 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDJ65466.1 - 0.00018 21.2 0.4 0.00029 20.5 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SR-25 PF10500.4 CDJ65466.1 - 0.055 12.9 12.9 0.12 11.8 8.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.13 CDJ65466.1 - 0.49 9.2 8.3 0.76 8.6 5.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med3 PF11593.3 CDJ65466.1 - 1.7 7.8 20.6 2.4 7.3 14.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.4 CDJ65466.1 - 2.9 6.0 9.8 4.2 5.5 6.8 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF755 PF05501.6 CDJ65467.1 - 0.0088 16.0 7.1 0.0088 16.0 4.9 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF755) RrnaAD PF00398.15 CDJ65468.1 - 4.2e-20 71.8 0.0 1.4e-18 66.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 CDJ65468.1 - 4.6e-05 23.1 0.0 0.0003 20.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ65468.1 - 0.00021 21.3 0.0 0.00044 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ65468.1 - 0.0051 17.3 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 CDJ65468.1 - 0.043 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 CDJ65468.1 - 0.096 13.0 0.0 0.24 11.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain BAF1_ABF1 PF04684.8 CDJ65469.1 - 0.0024 16.7 20.7 0.0024 16.7 14.4 10.0 10 1 1 11 11 11 2 BAF1 / ABF1 chromatin reorganising factor Ribosomal_S10 PF00338.17 CDJ65470.1 - 0.12 12.2 5.2 0.067 13.0 1.4 2.1 2 1 0 2 2 2 0 Ribosomal protein S10p/S20e Tau95 PF09734.4 CDJ65470.1 - 0.3 10.3 8.1 0.05 12.9 2.7 1.8 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit Ycf1 PF05758.7 CDJ65470.1 - 0.61 7.7 19.4 0.82 7.3 13.5 1.1 1 0 0 1 1 1 0 Ycf1 Na_trans_assoc PF06512.8 CDJ65470.1 - 8.3 6.3 13.1 16 5.3 9.1 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Actin PF00022.14 CDJ65471.1 - 3.2e-24 85.0 0.0 2.1e-16 59.3 0.0 2.6 1 1 1 2 2 2 2 Actin Dehydrin PF00257.14 CDJ65471.1 - 0.0066 16.7 0.3 2.4 8.4 0.0 3.2 3 1 0 3 3 3 1 Dehydrin DUF3446 PF11928.3 CDJ65471.1 - 1.9 8.7 33.5 0.62 10.2 1.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Claudin_2 PF13903.1 CDJ65472.1 - 0.018 14.7 7.9 0.027 14.1 5.4 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Helicase_C PF00271.26 CDJ65473.1 - 6e-14 51.6 0.6 4.8e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3240 PF11582.3 CDJ65473.1 - 0.0092 15.9 0.2 0.39 10.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3240) Spore_YtfJ PF09579.5 CDJ65473.1 - 4.9 7.0 5.7 3.2 7.6 0.2 3.0 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) SR-25 PF10500.4 CDJ65473.1 - 7.1 6.0 16.7 10 5.5 9.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ALMT PF11744.3 CDJ65474.1 - 1.7 7.1 7.6 3 6.3 5.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CPW_WPC PF09717.5 CDJ65476.1 - 3.2e-44 149.3 6.5 2.2e-12 47.3 1.3 5.5 5 1 0 5 5 5 5 Plasmodium falciparum domain of unknown function (CPW_WPC) Hamartin PF04388.7 CDJ65476.1 - 5.3 5.5 7.3 1.1 7.8 2.6 1.7 2 0 0 2 2 2 0 Hamartin protein Cullin_binding PF03556.10 CDJ65477.1 - 5.4e-23 81.3 0.3 2.4e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Cullin binding DUF3995 PF13160.1 CDJ65478.1 - 1 9.4 10.3 0.88 9.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) BSP_II PF05432.6 CDJ65479.1 - 0.01 15.1 0.9 0.01 15.1 0.6 3.3 4 0 0 4 4 4 0 Bone sialoprotein II (BSP-II) PH_BEACH PF14844.1 CDJ65479.1 - 0.1 12.4 0.2 0.32 10.8 0.1 1.8 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH DEAD PF00270.24 CDJ65480.1 - 5.7e-33 113.7 0.0 1.2e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD_3 PF13922.1 CDJ65480.1 - 1.8 8.8 8.1 12 6.1 5.6 2.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Cluap1 PF10234.4 CDJ65481.1 - 0.091 11.9 16.0 0.1 11.7 11.1 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 RAB3GAP2_N PF14655.1 CDJ65482.1 - 0.0023 16.9 0.8 0.0025 16.8 0.6 1.0 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DivIC PF04977.10 CDJ65482.1 - 0.0086 15.5 5.8 0.011 15.2 4.0 1.1 1 0 0 1 1 1 1 Septum formation initiator UPF0560 PF10577.4 CDJ65482.1 - 0.0091 14.3 0.3 0.0099 14.1 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 FCP1_C PF09309.5 CDJ65482.1 - 0.012 14.9 1.7 0.013 14.8 1.2 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Med15 PF09606.5 CDJ65482.1 - 0.014 13.6 11.4 0.014 13.6 7.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4232 PF14016.1 CDJ65482.1 - 0.018 14.7 1.2 0.025 14.2 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) TMEM51 PF15345.1 CDJ65482.1 - 0.04 13.6 0.6 0.037 13.7 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Spt20 PF12090.3 CDJ65482.1 - 0.047 13.0 2.8 0.048 12.9 2.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF1049 PF06305.6 CDJ65482.1 - 0.054 12.9 1.5 0.085 12.3 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Suf PF05843.9 CDJ65482.1 - 0.091 12.4 2.5 0.086 12.5 1.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex16 PF08610.5 CDJ65482.1 - 0.097 11.6 1.8 0.1 11.5 1.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TraH_2 PF06871.6 CDJ65482.1 - 0.1 12.0 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 TraH_2 TMEM154 PF15102.1 CDJ65482.1 - 0.12 12.0 4.1 0.14 11.8 2.8 1.1 1 0 0 1 1 1 0 TMEM154 protein family Oleosin PF01277.12 CDJ65482.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Oleosin Caldesmon PF02029.10 CDJ65482.1 - 0.15 10.4 7.3 0.16 10.3 5.1 1.0 1 0 0 1 1 1 0 Caldesmon Baculo_PP31 PF05311.6 CDJ65482.1 - 0.16 11.2 3.8 0.19 10.9 2.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) APC_CDC26 PF10471.4 CDJ65482.1 - 0.19 12.4 11.0 0.27 11.9 7.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 ERF PF04404.7 CDJ65482.1 - 0.19 11.2 6.4 0.23 11.0 4.4 1.1 1 0 0 1 1 1 0 ERF superfamily XRN_N PF03159.13 CDJ65482.1 - 0.21 10.9 1.9 0.22 10.8 1.3 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Peptidase_S49_N PF08496.5 CDJ65482.1 - 0.48 10.2 3.7 0.59 9.9 2.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF788 PF05620.6 CDJ65482.1 - 0.87 9.4 3.2 1.1 9.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) PHD_3 PF13922.1 CDJ65482.1 - 1.3 9.3 5.1 1.7 8.9 3.6 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx BAF1_ABF1 PF04684.8 CDJ65482.1 - 1.4 7.6 13.4 1.6 7.5 9.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4175 PF13779.1 CDJ65482.1 - 3.9 5.0 15.6 4.4 4.8 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TSA PF03249.8 CDJ65482.1 - 6.3 5.2 10.8 6.3 5.2 7.5 1.1 1 0 0 1 1 1 0 Type specific antigen tRNA-synt_1 PF00133.17 CDJ65483.1 - 1.7e-14 52.8 0.0 1.9e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Med15 PF09606.5 CDJ65484.1 - 0.00023 19.5 45.4 0.00023 19.5 31.5 18.9 14 5 1 16 16 16 4 ARC105 or Med15 subunit of Mediator complex non-fungal Cwf_Cwc_15 PF04889.7 CDJ65486.1 - 2.5 7.7 37.0 2.9 7.5 25.6 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 CDJ65486.1 - 7.2 5.9 36.3 9.2 5.5 25.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3899 PF13038.1 CDJ65487.1 - 0.41 10.8 0.0 0.41 10.8 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) DUF92 PF01940.11 CDJ65489.1 - 0.33 10.0 9.0 0.68 9.0 6.3 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF92 Hid1 PF12722.2 CDJ65489.1 - 0.86 7.2 19.2 1.3 6.5 13.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 CDJ65489.1 - 1.3 8.0 25.1 1.7 7.7 17.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF726 PF05277.7 CDJ65489.1 - 1.9 7.2 4.6 2.8 6.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Macoilin PF09726.4 CDJ65489.1 - 2.8 6.1 30.1 3.6 5.7 20.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Cellulose_synt PF03552.9 CDJ65489.1 - 5.7 5.0 6.6 7.8 4.6 4.6 1.2 1 0 0 1 1 1 0 Cellulose synthase RRM_1 PF00076.17 CDJ65491.1 - 5.3e-07 29.1 0.0 1.6e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ65491.1 - 3e-05 23.9 0.0 6.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EF1G PF00647.14 CDJ65492.1 - 2.5e-28 97.9 0.3 8.1e-26 89.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor 1 gamma, conserved domain Carb_anhydrase PF00194.16 CDJ65492.1 - 3.1e-17 62.3 2.7 1.5e-11 43.7 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic-type carbonic anhydrase GST_C PF00043.20 CDJ65492.1 - 1.2e-08 34.7 1.2 3.7e-08 33.2 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CDJ65492.1 - 1.8e-07 31.5 0.9 1.8e-07 31.5 0.6 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDJ65492.1 - 0.00022 21.0 8.2 0.00022 21.0 5.7 3.2 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CDJ65492.1 - 0.0016 18.5 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CDJ65492.1 - 0.09 12.9 0.0 0.37 10.9 0.0 2.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CDJ65492.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NPR3 PF03666.8 CDJ65493.1 - 2.7 6.4 7.3 3 6.2 5.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1183 PF06682.7 CDJ65493.1 - 4.4 6.8 11.6 5 6.6 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) TAF8_C PF10406.4 CDJ65494.1 - 0.015 15.3 0.2 0.015 15.3 0.1 2.2 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term SR-25 PF10500.4 CDJ65495.1 - 0.014 14.8 11.0 0.017 14.6 7.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gag_spuma PF03276.9 CDJ65495.1 - 0.29 9.4 5.0 0.3 9.3 3.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein PROL5-SMR PF15621.1 CDJ65495.1 - 0.43 11.0 3.5 0.84 10.0 2.4 1.6 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family MFS_1 PF07690.11 CDJ65497.1 - 0.00017 20.4 7.5 0.00051 18.8 5.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily SR-25 PF10500.4 CDJ65497.1 - 0.065 12.7 9.7 0.11 11.9 6.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1467 PF07330.7 CDJ65497.1 - 1.3 8.8 0.0 1.3 8.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1467) DUF755 PF05501.6 CDJ65497.1 - 3.9 7.5 12.7 6.1 6.9 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4064 PF13273.1 CDJ65499.1 - 0.2 11.7 4.1 35 4.5 2.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF165 PF02592.10 CDJ65499.1 - 0.43 10.7 6.5 2.8 8.1 4.2 2.2 1 1 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 Sdh_cyt PF01127.17 CDJ65499.1 - 2.7 7.8 10.8 6.4 6.6 3.0 2.2 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit AAA_22 PF13401.1 CDJ65500.1 - 1.1e-05 25.5 0.6 2.4e-05 24.4 0.4 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDJ65500.1 - 0.0047 16.6 8.9 0.042 13.5 0.0 3.7 3 1 0 3 3 3 1 Part of AAA domain ABC_tran PF00005.22 CDJ65500.1 - 0.0092 16.2 0.2 0.018 15.3 0.2 1.5 1 0 0 1 1 1 1 ABC transporter DUF935 PF06074.7 CDJ65500.1 - 0.92 8.1 11.8 1.9 7.0 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF935) YchF-GTPase_C PF06071.8 CDJ65501.1 - 2.4e-40 136.2 1.4 4.7e-40 135.2 0.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CDJ65501.1 - 1.1e-16 60.8 0.0 7.1e-16 58.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDJ65501.1 - 4.5e-06 26.0 0.0 1.5e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 CDJ65501.1 - 0.011 16.6 0.1 0.63 10.8 0.0 2.7 1 1 0 1 1 1 0 AAA domain PEP-utilisers_N PF05524.8 CDJ65501.1 - 0.031 14.0 1.4 0.078 12.7 1.0 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TGS PF02824.16 CDJ65501.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 TGS domain AAA_14 PF13173.1 CDJ65501.1 - 0.089 12.6 0.0 0.57 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CDJ65501.1 - 0.11 12.8 1.8 4.4 7.6 0.0 3.1 2 1 1 3 3 3 0 AAA domain DUF972 PF06156.8 CDJ65501.1 - 4.8 7.5 8.4 2.9e+02 1.8 5.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Pkinase PF00069.20 CDJ65502.1 - 5e-73 245.4 0.2 2.8e-72 242.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65502.1 - 2.6e-38 131.5 0.0 6.6e-38 130.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDJ65502.1 - 0.00015 21.6 0.2 0.00015 21.6 0.2 4.3 3 2 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDJ65502.1 - 0.031 13.8 0.1 0.031 13.8 0.1 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase ADIP PF11559.3 CDJ65503.1 - 0.035 13.9 3.7 0.062 13.1 2.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 CDJ65504.1 - 0.0063 16.2 2.7 0.0063 16.2 1.9 3.1 4 0 0 4 4 4 1 Homeobox associated leucine zipper Toxin_50 PF15530.1 CDJ65505.1 - 0.017 15.0 0.6 0.044 13.6 0.2 1.8 2 0 0 2 2 2 0 Putative toxin 50 Topoisom_bac PF01131.15 CDJ65506.1 - 3.8e-05 22.6 0.1 0.099 11.4 0.0 2.1 1 1 1 2 2 2 2 DNA topoisomerase Pkinase PF00069.20 CDJ65507.1 - 6.9e-35 120.4 0.0 9.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65507.1 - 9.5e-16 57.6 0.0 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 CDJ65507.1 - 8.2e-10 38.6 0.5 8.4e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDJ65507.1 - 2.9e-09 36.3 1.4 1.8e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDJ65507.1 - 3e-09 35.5 0.9 0.00063 18.8 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CDJ65507.1 - 1.8e-08 33.5 1.2 0.00059 19.5 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CDJ65507.1 - 4.8e-07 28.8 5.9 0.00084 18.5 0.5 3.1 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.1 CDJ65507.1 - 0.00012 21.1 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF2036 PF09724.4 CDJ65509.1 - 1.5e-09 37.5 0.0 0.00049 19.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) FAD_binding_3 PF01494.14 CDJ65510.1 - 5.2e-60 203.3 3.6 1e-30 107.0 0.5 4.0 4 0 0 4 4 4 3 FAD binding domain DAO PF01266.19 CDJ65510.1 - 0.00012 21.0 0.1 0.00034 19.6 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDJ65510.1 - 0.00015 20.7 0.2 0.00015 20.7 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 CDJ65510.1 - 0.00017 20.6 0.6 0.00039 19.4 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CDJ65510.1 - 0.00021 21.2 0.3 0.00051 19.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CDJ65510.1 - 0.00048 20.1 1.1 0.0019 18.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CDJ65510.1 - 0.00083 18.5 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CDJ65510.1 - 0.0069 14.9 0.1 0.013 14.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 CDJ65510.1 - 0.0098 15.9 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PepSY_2 PF13670.1 CDJ65510.1 - 0.94 9.4 9.8 0.076 12.9 1.7 3.2 2 0 0 2 2 1 0 Peptidase propeptide and YPEB domain ThiF PF00899.16 CDJ65510.1 - 3.2 7.5 5.4 2.9 7.7 0.4 2.4 2 0 0 2 2 2 0 ThiF family Pkinase PF00069.20 CDJ65511.1 - 3.4e-23 82.1 0.0 3.4e-11 42.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65511.1 - 1e-09 37.8 0.0 2.8e-06 26.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pro_dh PF01619.13 CDJ65512.1 - 1e-55 188.9 0.0 1.6e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Hom_end_hint PF05203.11 CDJ65513.1 - 0.0085 15.8 1.7 0.0085 15.8 1.2 1.7 2 0 0 2 2 2 1 Hom_end-associated Hint SAPS PF04499.10 CDJ65513.1 - 0.022 13.4 9.6 0.007 15.0 4.7 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 CDJ65513.1 - 0.3 9.3 5.7 0.47 8.6 4.0 1.3 1 0 0 1 1 1 0 Membrane transport protein LMBR1 PF04791.11 CDJ65513.1 - 0.37 9.3 4.4 0.51 8.8 3.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.9 CDJ65513.1 - 0.45 8.4 15.2 0.81 7.6 10.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Otopetrin PF03189.8 CDJ65513.1 - 0.64 8.9 4.4 0.091 11.7 0.8 1.4 2 0 0 2 2 2 0 Otopetrin GAGA_bind PF06217.7 CDJ65513.1 - 2 8.3 22.3 0.46 10.4 11.3 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family SPX PF03105.14 CDJ65513.1 - 2.2 7.9 17.6 0.17 11.6 8.8 1.6 2 0 0 2 2 2 0 SPX domain Tim54 PF11711.3 CDJ65513.1 - 6.4 5.2 16.3 13 4.2 11.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Gti1_Pac2 PF09729.4 CDJ65513.1 - 8.1 6.2 14.9 6 6.7 8.5 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family SR-25 PF10500.4 CDJ65514.1 - 0.039 13.4 33.1 0.48 9.8 9.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SAPS PF04499.10 CDJ65514.1 - 0.25 9.9 14.0 0.26 9.8 9.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDV3 PF15359.1 CDJ65514.1 - 0.39 10.8 19.5 1 9.4 6.4 2.4 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 Peptidase_S64 PF08192.6 CDJ65514.1 - 4.5 5.4 21.7 5.1 5.2 15.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.5 CDJ65514.1 - 6.2 5.1 24.5 8.4 4.6 17.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.8 CDJ65515.1 - 0.00084 18.3 18.4 0.00084 18.3 12.8 3.1 2 1 1 3 3 2 1 BAF1 / ABF1 chromatin reorganising factor Sporozoite_P67 PF05642.6 CDJ65515.1 - 0.0076 14.1 0.1 0.0076 14.1 0.0 2.0 2 0 0 2 2 2 1 Sporozoite P67 surface antigen Kelch_4 PF13418.1 CDJ65515.1 - 0.019 14.7 1.0 2 8.2 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain SAGA-Tad1 PF12767.2 CDJ65515.1 - 0.027 14.1 29.2 0.1 12.2 10.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDJ65515.1 - 0.046 11.9 54.4 0.26 9.4 19.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.1 CDJ65515.1 - 0.062 12.5 23.5 0.47 9.6 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) PDZ_2 PF13180.1 CDJ65515.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Herpes_UL87 PF03043.9 CDJ65515.1 - 0.11 10.9 8.6 0.045 12.1 0.5 2.0 2 0 0 2 2 2 0 Herpesvirus UL87 family Kelch_3 PF13415.1 CDJ65515.1 - 0.19 11.9 0.0 0.19 11.9 0.0 4.1 6 0 0 6 6 3 0 Galactose oxidase, central domain SOBP PF15279.1 CDJ65515.1 - 0.27 11.5 24.6 1.7 8.9 5.5 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein DUF572 PF04502.8 CDJ65515.1 - 0.61 9.2 35.1 1.7 7.8 7.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) PLRV_ORF5 PF01690.12 CDJ65515.1 - 0.7 8.9 26.1 1.8 7.6 6.4 2.0 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein SelP_N PF04592.9 CDJ65515.1 - 1.2 8.5 20.9 0.11 11.8 4.5 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF3807 PF12720.2 CDJ65515.1 - 2.8 8.0 39.8 2.8 8.0 8.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SPX PF03105.14 CDJ65515.1 - 2.9 7.5 26.8 3.2 7.4 3.7 2.1 2 0 0 2 2 2 0 SPX domain Gti1_Pac2 PF09729.4 CDJ65515.1 - 3.2 7.5 18.5 2.5 7.9 2.4 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Ycf1 PF05758.7 CDJ65515.1 - 3.4 5.2 29.0 1.8 6.1 6.5 2.0 2 0 0 2 2 2 0 Ycf1 Hid1 PF12722.2 CDJ65515.1 - 3.8 5.0 28.5 0.92 7.1 5.8 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Hom_end_hint PF05203.11 CDJ65515.1 - 3.9 7.1 16.1 0.56 9.9 1.6 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint CDC45 PF02724.9 CDJ65515.1 - 4.4 5.2 29.5 1.4 6.8 8.3 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 CDJ65515.1 - 6.6 6.0 31.5 0.33 10.3 5.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4366 PF14283.1 CDJ65515.1 - 6.9 6.0 15.4 4.7 6.5 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SR-25 PF10500.4 CDJ65515.1 - 7.2 6.0 42.2 1.8 7.9 5.3 2.6 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein GOLD_2 PF13897.1 CDJ65515.1 - 7.6 6.7 17.3 1.5 9.0 4.0 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Rhabdo_ncap PF00945.13 CDJ65515.1 - 7.7 4.9 12.3 0.36 9.3 1.1 2.1 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein DUF1777 PF08648.7 CDJ65517.1 - 6.4 6.4 20.9 7.5 6.2 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) YL1 PF05764.8 CDJ65518.1 - 2.8e-20 72.9 32.9 2.8e-20 72.9 22.8 1.7 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 CDJ65518.1 - 3e-10 39.4 0.1 4.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF4638 PF15472.1 CDJ65518.1 - 4.1 6.9 21.8 7.9 5.9 15.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Med15 PF09606.5 CDJ65519.1 - 8e-05 21.0 37.6 9.2e-05 20.8 26.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ65519.1 - 0.18 9.9 34.0 0.2 9.8 23.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MMR1 PF08505.5 CDJ65519.1 - 2.5 8.0 17.3 3.2 7.7 12.0 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.8 CDJ65519.1 - 2.5 7.9 26.6 3 7.6 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDJ65519.1 - 3 7.6 7.3 3.8 7.3 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.1 CDJ65519.1 - 3.5 5.2 35.5 4.2 4.9 24.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) YjgP_YjgQ PF03739.9 CDJ65519.1 - 8.2 5.0 6.2 11 4.6 4.3 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family SR-25 PF10500.4 CDJ65520.1 - 0.14 11.6 44.1 0.021 14.2 8.0 3.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Mem_trans PF03547.13 CDJ65522.1 - 0.075 11.3 2.9 0.087 11.0 2.0 1.3 1 0 0 1 1 1 0 Membrane transport protein Med15 PF09606.5 CDJ65522.1 - 0.87 7.7 46.1 1.1 7.4 32.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal efThoc1 PF11957.3 CDJ65523.1 - 0.013 14.0 0.0 0.021 13.3 0.0 1.2 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor ATP-synt_ab_N PF02874.18 CDJ65524.1 - 0.00019 21.5 0.4 0.00032 20.8 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CDJ65524.1 - 0.012 15.5 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 HAS barrel domain PhageMin_Tail PF10145.4 CDJ65524.1 - 0.044 13.4 4.7 0.051 13.2 3.3 1.1 1 0 0 1 1 1 0 Phage-related minor tail protein PTS_EIIC_2 PF13303.1 CDJ65524.1 - 0.53 9.0 3.5 0.58 8.9 2.5 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Ribosomal_60s PF00428.14 CDJ65524.1 - 3.5 8.0 12.0 6.9 7.1 8.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein XRN_N PF03159.13 CDJ65525.1 - 2.1e-08 33.8 0.0 2.1e-08 33.8 0.0 4.1 5 0 0 5 5 5 1 XRN 5'-3' exonuclease N-terminus DUF793 PF05633.6 CDJ65525.1 - 0.003 16.4 5.2 0.003 16.4 3.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF793) CDK2AP PF09806.4 CDJ65525.1 - 0.0073 16.5 12.9 0.0073 16.5 9.0 6.0 4 2 0 4 4 4 2 Cyclin-dependent kinase 2-associated protein zf-DHHC PF01529.15 CDJ65525.1 - 9.3 5.6 11.4 1.5 8.2 0.0 3.6 4 0 0 4 4 4 0 DHHC palmitoyltransferase XRN_N PF03159.13 CDJ65526.1 - 2.9e-11 43.2 3.9 4.7e-07 29.4 2.4 3.1 1 1 2 3 3 2 2 XRN 5'-3' exonuclease N-terminus Suf PF05843.9 CDJ65526.1 - 0.0066 16.2 19.1 0.0079 15.9 13.2 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDJ65526.1 - 0.053 12.9 22.3 0.065 12.6 15.4 1.0 1 0 0 1 1 1 0 Vta1 like Raftlin PF15250.1 CDJ65526.1 - 0.054 12.0 13.4 0.063 11.8 9.3 1.0 1 0 0 1 1 1 0 Raftlin SUV3_C PF12513.3 CDJ65526.1 - 0.061 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal GAGA_bind PF06217.7 CDJ65526.1 - 0.065 13.1 14.3 0.079 12.9 9.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CKAP2_C PF15297.1 CDJ65526.1 - 0.087 11.6 16.5 0.11 11.2 11.5 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CDC45 PF02724.9 CDJ65526.1 - 0.1 10.6 13.9 0.12 10.4 9.6 1.0 1 0 0 1 1 1 0 CDC45-like protein ARF7EP_C PF14949.1 CDJ65526.1 - 0.15 12.5 17.0 0.076 13.4 10.1 1.7 1 1 1 2 2 2 0 ARF7 effector protein C-terminus Presenilin PF01080.12 CDJ65526.1 - 0.16 10.7 11.7 0.17 10.6 8.1 1.0 1 0 0 1 1 1 0 Presenilin XAP5 PF04921.9 CDJ65526.1 - 0.16 11.5 7.4 0.2 11.1 5.1 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF4045 PF13254.1 CDJ65526.1 - 0.21 10.8 13.7 0.24 10.6 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDJ65526.1 - 0.23 11.1 19.0 0.27 10.8 13.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Spc7_N PF15402.1 CDJ65526.1 - 0.31 9.0 23.6 0.37 8.7 16.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Mito_fiss_reg PF05308.6 CDJ65526.1 - 0.31 10.3 12.9 0.38 10.0 9.0 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Sec62 PF03839.11 CDJ65526.1 - 0.32 10.3 9.5 0.41 10.0 6.6 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 CAF-1_p150 PF11600.3 CDJ65526.1 - 0.37 10.1 22.3 0.48 9.7 15.5 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SPX PF03105.14 CDJ65526.1 - 0.39 10.4 13.2 0.48 10.1 9.1 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.4 CDJ65526.1 - 0.51 8.5 11.8 0.6 8.3 8.1 1.0 1 0 0 1 1 1 0 Transmembrane protein FAM60A PF15396.1 CDJ65526.1 - 0.56 9.9 12.7 0.77 9.4 8.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDJ65526.1 - 0.58 9.9 16.1 0.76 9.5 11.1 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_U57 PF05582.7 CDJ65526.1 - 0.63 8.9 6.4 0.83 8.5 4.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Zip PF02535.17 CDJ65526.1 - 0.65 8.9 4.9 0.81 8.6 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cellulose_synt PF03552.9 CDJ65526.1 - 0.86 7.8 2.9 0.98 7.6 2.0 1.0 1 0 0 1 1 1 0 Cellulose synthase CobT PF06213.7 CDJ65526.1 - 0.96 8.5 17.3 1.4 7.9 12.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Parvo_coat PF00740.13 CDJ65526.1 - 0.97 8.3 14.8 1.1 8.1 10.3 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF4048 PF13257.1 CDJ65526.1 - 1 8.9 18.9 1.4 8.5 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) DUF1510 PF07423.6 CDJ65526.1 - 1.2 8.4 20.9 1.5 8.1 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDK5_activator PF03261.10 CDJ65526.1 - 1.5 8.0 11.9 1.8 7.8 8.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF1675 PF07897.6 CDJ65526.1 - 1.9 8.2 14.2 2.3 8.0 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FLO_LFY PF01698.11 CDJ65526.1 - 2 7.1 15.7 2.4 6.9 10.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF913 PF06025.7 CDJ65526.1 - 2.1 7.0 11.2 2.5 6.7 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF572 PF04502.8 CDJ65526.1 - 2.1 7.4 17.9 2.6 7.1 12.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dicty_REP PF05086.7 CDJ65526.1 - 2.3 5.8 11.3 2.6 5.7 7.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ycf1 PF05758.7 CDJ65526.1 - 3.1 5.3 12.6 3.5 5.2 8.7 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CDJ65526.1 - 3.1 7.6 11.4 4 7.2 7.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Caldesmon PF02029.10 CDJ65526.1 - 4 5.7 17.8 4.8 5.4 12.3 1.0 1 0 0 1 1 1 0 Caldesmon PAT1 PF09770.4 CDJ65526.1 - 4.1 5.5 40.3 4.8 5.2 28.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4011 PF13195.1 CDJ65526.1 - 4.4 7.2 8.7 5.8 6.8 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Herpes_UL87 PF03043.9 CDJ65526.1 - 5.5 5.2 6.7 6.1 5.0 4.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4544 PF15077.1 CDJ65526.1 - 5.6 6.4 7.7 6.7 6.1 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Adaptin_binding PF10199.4 CDJ65526.1 - 6.1 7.1 19.9 8.6 6.6 13.8 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SR-25 PF10500.4 CDJ65526.1 - 7.1 6.0 25.6 14 5.0 17.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rtf2 PF04641.7 CDJ65526.1 - 7.9 5.5 16.9 11 5.1 11.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger GPCR_chapero_1 PF11904.3 CDJ65526.1 - 8.5 5.4 13.9 11 5.0 9.6 1.2 1 0 0 1 1 1 0 GPCR-chaperone Herpes_DNAp_acc PF04929.7 CDJ65526.1 - 8.5 5.2 19.6 11 4.9 13.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SAPS PF04499.10 CDJ65526.1 - 8.6 4.8 14.4 10 4.6 10.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AvrE PF11725.3 CDJ65526.1 - 8.8 3.2 25.2 10 2.9 17.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor SprA-related PF12118.3 CDJ65526.1 - 8.9 5.5 46.2 12 5.1 32.0 1.1 1 0 0 1 1 1 0 SprA-related family TP53IP5 PF15331.1 CDJ65526.1 - 9 6.1 12.3 11 5.8 8.5 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Pkinase PF00069.20 CDJ65527.1 - 2e-25 89.4 0.0 2.3e-23 82.6 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65527.1 - 2.4e-10 39.9 0.0 0.00032 19.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDJ65527.1 - 0.0093 14.9 0.0 0.38 9.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Ras PF00071.17 CDJ65528.1 - 3e-50 169.7 3.1 1.5e-37 128.4 0.0 2.8 3 0 0 3 3 3 2 Ras family Miro PF08477.8 CDJ65528.1 - 8.6e-16 58.5 1.2 2.2e-07 31.3 0.0 3.1 3 0 0 3 3 3 2 Miro-like protein Arf PF00025.16 CDJ65528.1 - 5.5e-14 51.7 4.8 3e-12 46.1 0.0 3.0 2 1 0 3 3 3 2 ADP-ribosylation factor family AAA_16 PF13191.1 CDJ65528.1 - 0.00024 21.1 0.7 0.00024 21.1 0.5 2.7 2 1 0 2 2 1 1 AAA ATPase domain ABC_tran PF00005.22 CDJ65528.1 - 0.00082 19.6 5.0 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Gtr1_RagA PF04670.7 CDJ65528.1 - 0.00084 18.5 2.2 0.58 9.2 0.2 2.8 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF258 PF03193.11 CDJ65528.1 - 0.003 16.7 0.0 0.011 14.9 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CDJ65528.1 - 0.0034 17.3 0.0 0.022 14.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDJ65528.1 - 0.004 16.6 0.3 0.021 14.2 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CDJ65528.1 - 0.025 14.1 0.1 0.072 12.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 CDJ65528.1 - 0.039 12.9 0.3 0.039 12.9 0.2 2.0 2 0 0 2 2 2 0 Septin Med15 PF09606.5 CDJ65528.1 - 0.042 12.0 52.8 0.14 10.3 21.0 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_22 PF13401.1 CDJ65528.1 - 0.043 13.9 0.2 0.043 13.9 0.1 3.1 2 2 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CDJ65528.1 - 0.21 11.3 3.4 0.21 11.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 CDJ65528.1 - 7.8 5.8 6.0 25 4.1 0.0 3.0 2 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain RR_TM4-6 PF06459.7 CDJ65530.1 - 6.1 6.6 15.8 16 5.2 10.9 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Chorion_2 PF03964.10 CDJ65532.1 - 0.085 13.4 11.6 0.13 12.8 8.1 1.4 1 1 0 1 1 1 0 Chorion family 2 CAF-1_p150 PF11600.3 CDJ65532.1 - 0.5 9.7 23.8 0.64 9.3 16.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDJ65532.1 - 5.9 6.2 27.4 9.2 5.6 19.0 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suc_Fer-like PF06999.7 CDJ65532.1 - 7.9 6.4 10.6 96 2.8 7.4 1.9 1 1 0 1 1 1 0 Sucrase/ferredoxin-like RAP1 PF07218.6 CDJ65532.1 - 8 4.4 7.4 8 4.4 5.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MAT1 PF06391.8 CDJ65533.1 - 0.028 13.9 9.9 0.035 13.6 6.9 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF3450 PF11932.3 CDJ65533.1 - 0.028 13.6 10.2 0.032 13.5 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MOR2-PAG1_mid PF14228.1 CDJ65533.1 - 0.13 9.7 0.9 0.15 9.6 0.6 1.0 1 0 0 1 1 1 0 Cell morphogenesis central region Fcf1 PF04900.7 CDJ65533.1 - 0.2 11.7 8.2 6.6 6.8 0.0 2.6 2 1 1 3 3 3 0 Fcf1 Presenilin PF01080.12 CDJ65533.1 - 0.2 10.4 1.5 0.21 10.3 1.1 1.1 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.3 CDJ65533.1 - 0.43 9.2 16.2 0.5 9.0 11.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Maf1 PF09174.5 CDJ65533.1 - 0.84 9.4 3.7 1.2 8.9 2.6 1.2 1 0 0 1 1 1 0 Maf1 regulator Adeno_PIX PF03955.9 CDJ65533.1 - 1.6 9.2 7.5 2.7 8.5 5.2 1.4 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) RR_TM4-6 PF06459.7 CDJ65533.1 - 1.6 8.5 9.0 2.2 8.1 6.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAD-oxidase_C PF02913.14 CDJ65533.1 - 4.3 6.5 6.5 6.5 6.0 4.5 1.3 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain Caps_synth_GfcC PF06251.6 CDJ65533.1 - 6.8 5.7 10.5 8.8 5.4 7.3 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Med15 PF09606.5 CDJ65534.1 - 0.0018 16.6 36.2 0.0025 16.0 25.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Y_phosphatase3 PF13350.1 CDJ65534.1 - 0.019 15.2 7.1 0.019 15.2 5.0 2.6 2 2 1 3 3 3 0 Tyrosine phosphatase family PAT1 PF09770.4 CDJ65534.1 - 0.33 9.1 19.1 0.44 8.7 13.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2756 PF10956.3 CDJ65534.1 - 1.2 9.4 24.8 0.16 12.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) DUF1388 PF07142.7 CDJ65535.1 - 0.053 13.2 9.4 0.06 13.0 1.6 3.2 3 0 0 3 3 3 0 Repeat of unknown function (DUF1388) MIP-T3 PF10243.4 CDJ65535.1 - 8 4.7 71.6 11 4.3 49.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MORN PF02493.15 CDJ65536.1 - 5.3e-20 69.8 10.4 1.8e-07 30.5 0.8 3.4 3 0 0 3 3 3 3 MORN repeat 2Fe-2S_Ferredox PF11591.3 CDJ65538.1 - 0.12 12.0 2.4 0.25 11.0 1.7 1.5 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide Mito_carr PF00153.22 CDJ65539.1 - 1.1e-23 82.7 5.9 3.9e-19 68.1 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein Herpes_UL17 PF04559.7 CDJ65541.1 - 5.8 5.3 16.1 7.2 5.0 11.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein PHO4 PF01384.15 CDJ65542.1 - 7.9e-32 110.1 8.6 9.9e-32 109.8 6.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family CDC27 PF09507.5 CDJ65543.1 - 1.1 8.3 41.8 1.3 8.1 29.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ribosomal_L7Ae PF01248.21 CDJ65547.1 - 3e-19 68.3 0.0 6.6e-19 67.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SR-25 PF10500.4 CDJ65547.1 - 1.3 8.4 16.7 0.023 14.1 6.8 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3246 PF11596.3 CDJ65547.1 - 3.9 6.6 6.4 78 2.4 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) RCC1 PF00415.13 CDJ65548.1 - 9.2e-31 105.8 14.5 3.5e-09 36.7 0.7 7.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ65548.1 - 2e-24 84.5 25.6 2.6e-10 39.6 1.2 6.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Fe-S_biosyn PF01521.15 CDJ65549.1 - 2.2e-08 33.9 0.2 2.2e-05 24.3 0.0 2.7 2 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis NDK PF00334.14 CDJ65550.1 - 1.3e-26 92.9 0.0 2.4e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 Nucleoside diphosphate kinase AAA_5 PF07728.9 CDJ65551.1 - 1.4e-105 348.7 0.0 7.3e-21 74.3 0.0 10.2 9 1 0 9 9 9 8 AAA domain (dynein-related subfamily) AAA PF00004.24 CDJ65551.1 - 5.4e-21 75.1 0.0 0.0036 17.5 0.0 7.1 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 CDJ65551.1 - 1.4e-19 69.9 0.0 0.00032 20.2 0.0 7.6 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CDJ65551.1 - 5.5e-12 46.5 0.0 0.38 11.5 0.0 6.7 6 0 0 6 6 6 3 AAA domain AAA_22 PF13401.1 CDJ65551.1 - 1.5e-10 41.3 17.5 0.038 14.1 0.0 9.2 10 1 0 10 10 8 3 AAA domain UPF0079 PF02367.12 CDJ65551.1 - 1.6e-09 37.4 2.7 0.058 13.0 0.3 6.0 6 0 0 6 6 6 1 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 CDJ65551.1 - 1.8e-08 34.3 0.0 0.0016 18.3 0.0 5.6 6 0 0 6 6 6 1 AAA domain AAA_18 PF13238.1 CDJ65551.1 - 5e-06 26.8 0.0 3.2 8.0 0.0 6.2 6 0 0 6 6 6 1 AAA domain AAA_16 PF13191.1 CDJ65551.1 - 2.2e-05 24.5 5.0 0.00074 19.5 0.6 17.8 15 5 2 17 17 11 6 AAA ATPase domain AAA_29 PF13555.1 CDJ65551.1 - 5.3e-05 22.6 4.7 17 5.0 0.0 6.7 7 0 0 7 7 7 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CDJ65551.1 - 0.00025 21.1 0.0 74 3.5 0.0 6.0 6 0 0 6 6 6 0 RNA helicase Miro PF08477.8 CDJ65551.1 - 0.0092 16.4 0.1 75 3.8 0.0 5.1 5 0 0 5 5 5 0 Miro-like protein VWA PF00092.23 CDJ65551.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain Rad17 PF03215.10 CDJ65551.1 - 0.65 8.6 0.4 14 4.1 0.0 2.8 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 CDJ65551.1 - 0.66 9.6 0.0 41 3.8 0.0 3.9 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B DUF755 PF05501.6 CDJ65552.1 - 0.00051 20.0 16.1 0.00051 20.0 11.2 13.5 14 1 0 14 14 14 1 Domain of unknown function (DUF755) GCV_T PF01571.16 CDJ65553.1 - 0.0031 16.9 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Ribosomal_60s PF00428.14 CDJ65553.1 - 0.011 16.1 5.6 0.011 16.1 3.9 3.3 3 1 0 3 3 3 0 60s Acidic ribosomal protein GCV_T_C PF08669.6 CDJ65553.1 - 0.02 14.9 0.6 0.063 13.3 0.0 2.1 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain GTP_EFTU PF00009.22 CDJ65554.1 - 2.6e-23 82.4 0.0 1.5e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDJ65554.1 - 4.7e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CDJ65554.1 - 0.0035 17.1 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 2 Dynamin family G-alpha PF00503.15 CDJ65554.1 - 0.12 11.0 0.2 0.2 10.3 0.1 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Miro PF08477.8 CDJ65554.1 - 0.2 12.1 0.0 13 6.2 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 CDJ65554.1 - 0.35 10.3 0.1 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.20 CDJ65555.1 - 4.2e-49 167.0 0.0 1.2e-48 165.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65555.1 - 1e-23 83.7 0.0 1.1e-16 60.7 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CDJ65555.1 - 6.7e-05 21.9 1.5 0.015 14.2 0.0 2.5 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.17 CDJ65555.1 - 0.00082 18.7 0.1 0.002 17.5 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CDJ65555.1 - 0.0023 17.7 0.1 0.0053 16.5 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CDJ65555.1 - 0.027 13.5 0.1 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spore_coat_CotO PF14153.1 CDJ65555.1 - 0.033 13.6 12.7 0.063 12.7 8.8 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Seadorna_VP7 PF07387.6 CDJ65555.1 - 0.065 12.0 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 CDJ65555.1 - 0.097 11.9 0.1 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CDC45 PF02724.9 CDJ65555.1 - 0.15 10.0 14.8 0.21 9.5 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CDJ65555.1 - 0.23 9.6 26.3 0.34 9.1 18.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Red1 PF07964.6 CDJ65555.1 - 0.26 9.3 14.8 0.34 9.0 10.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 SAPS PF04499.10 CDJ65555.1 - 1.3 7.5 10.7 2.2 6.8 7.4 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF566 PF04484.7 CDJ65555.1 - 1.6 8.2 21.9 2.7 7.4 15.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) Lin-8 PF03353.10 CDJ65555.1 - 4.4 6.4 16.6 6.7 5.8 11.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MIP-T3 PF10243.4 CDJ65555.1 - 4.6 5.5 33.0 7.1 4.9 22.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_25 PF13481.1 CDJ65556.1 - 0.0036 16.7 0.1 0.013 14.9 0.1 2.0 1 0 0 1 1 1 1 AAA domain Calcipressin PF04847.7 CDJ65557.1 - 1.4 8.4 10.3 0.025 14.1 1.1 2.2 2 1 0 2 2 2 0 Calcipressin CAF-1_p150 PF11600.3 CDJ65557.1 - 9.3 5.5 29.0 0.22 10.9 10.7 2.5 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMEM51 PF15345.1 CDJ65560.1 - 0.011 15.3 0.7 0.011 15.3 0.5 4.4 3 2 2 5 5 5 0 Transmembrane protein 51 TMEM154 PF15102.1 CDJ65560.1 - 0.033 13.8 1.7 1.5 8.5 0.0 3.3 3 0 0 3 3 3 0 TMEM154 protein family Peptidase_M56 PF05569.6 CDJ65560.1 - 4.4 6.1 8.2 1.9 7.4 2.7 2.2 1 1 1 2 2 2 0 BlaR1 peptidase M56 Apt1 PF10351.4 CDJ65560.1 - 5.4 5.7 9.4 6.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ribosomal_60s PF00428.14 CDJ65561.1 - 9.7e-06 25.9 1.5 9.7e-06 25.9 1.1 4.5 3 1 0 3 3 3 1 60s Acidic ribosomal protein Activator_LAG-3 PF11498.3 CDJ65561.1 - 2 7.0 26.8 3 6.4 18.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AAA_23 PF13476.1 CDJ65563.1 - 2.2 8.5 12.1 1.4 9.1 0.3 2.2 2 0 0 2 2 2 0 AAA domain SprA-related PF12118.3 CDJ65563.1 - 2.9 7.1 59.6 0.15 11.3 19.5 2.1 2 0 0 2 2 2 0 SprA-related family RskA PF10099.4 CDJ65566.1 - 0.00062 19.5 23.2 0.049 13.3 10.6 2.3 2 0 0 2 2 2 2 Anti-sigma-K factor rskA FHIPEP PF00771.15 CDJ65566.1 - 0.00086 17.7 12.2 0.001 17.5 8.5 1.0 1 0 0 1 1 1 1 FHIPEP family MCR_alpha PF02249.12 CDJ65566.1 - 0.27 11.2 2.5 1.6 8.7 0.5 2.4 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF1604 PF07713.8 CDJ65566.1 - 2.4 8.0 10.9 0.24 11.1 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1604) MDFI PF15316.1 CDJ65567.1 - 1 9.3 35.9 0.041 13.8 4.2 3.4 3 0 0 3 3 3 0 MyoD family inhibitor SR-25 PF10500.4 CDJ65567.1 - 1.5 8.2 56.5 0.027 13.9 12.8 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDJ65567.1 - 2.8 8.3 15.1 9.1 6.7 10.5 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein SNF2_N PF00176.18 CDJ65568.1 - 3.7e-16 58.7 0.0 3.7e-16 58.7 0.0 1.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain Ribosomal_L4 PF00573.17 CDJ65570.1 - 2.2e-15 56.5 5.5 1.1e-07 31.3 2.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L4/L1 family DUF4657 PF15552.1 CDJ65570.1 - 0.053 12.8 0.2 0.081 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) ELO PF01151.13 CDJ65571.1 - 9.2e-63 211.8 22.3 1.1e-62 211.5 15.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Activator_LAG-3 PF11498.3 CDJ65573.1 - 0.00062 18.6 26.1 0.00062 18.6 18.1 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Med15 PF09606.5 CDJ65573.1 - 0.099 10.8 27.2 0.093 10.9 18.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ65573.1 - 4.7 5.3 23.4 4.9 5.2 16.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lactamase_B_2 PF12706.2 CDJ65574.1 - 2.3e-07 30.5 0.0 6.1e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDJ65574.1 - 0.00029 20.5 1.0 0.00089 18.9 0.7 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DivIC PF04977.10 CDJ65574.1 - 0.25 10.8 8.9 0.44 10.0 6.1 1.3 1 0 0 1 1 1 0 Septum formation initiator FCP1_C PF09309.5 CDJ65574.1 - 0.73 9.0 7.5 0.048 12.9 1.8 1.5 2 0 0 2 2 2 0 FCP1, C-terminal FPN1 PF06963.7 CDJ65575.1 - 0.0054 15.1 0.5 0.0057 15.0 0.4 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MARCKS PF02063.12 CDJ65575.1 - 0.01 15.7 16.6 0.011 15.6 11.5 1.0 1 0 0 1 1 1 0 MARCKS family FHIPEP PF00771.15 CDJ65575.1 - 0.014 13.8 6.1 0.016 13.5 4.2 1.0 1 0 0 1 1 1 0 FHIPEP family DcuC PF03606.10 CDJ65575.1 - 0.045 11.9 1.8 0.051 11.7 1.2 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF677 PF05055.7 CDJ65575.1 - 0.054 12.1 0.1 0.054 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) MAS20 PF02064.10 CDJ65575.1 - 0.18 11.7 8.2 0.033 14.1 2.4 1.8 2 0 0 2 2 2 0 MAS20 protein import receptor HemX PF04375.9 CDJ65575.1 - 0.21 10.1 20.9 0.25 9.8 14.5 1.1 1 0 0 1 1 1 0 HemX Suf PF05843.9 CDJ65575.1 - 0.26 10.9 14.3 0.27 10.9 9.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2048 PF09752.4 CDJ65575.1 - 0.32 9.8 5.3 0.35 9.6 3.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) ERbeta_N PF12497.3 CDJ65575.1 - 0.33 10.7 4.4 0.49 10.2 3.0 1.4 1 0 0 1 1 1 0 Estrogen receptor beta DUF3413 PF11893.3 CDJ65575.1 - 0.51 9.1 3.9 0.61 8.9 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) MSP1_C PF07462.6 CDJ65575.1 - 0.53 8.6 5.5 0.58 8.4 3.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus R_equi_Vir PF05526.6 CDJ65575.1 - 0.55 9.8 8.6 0.71 9.4 6.0 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein LCE PF14672.1 CDJ65575.1 - 0.65 10.5 5.4 0.42 11.1 2.0 2.1 1 1 1 2 2 2 0 Late cornified envelope DUF3533 PF12051.3 CDJ65575.1 - 1.1 7.9 6.8 1.1 7.8 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Pex16 PF08610.5 CDJ65575.1 - 1.1 8.1 6.8 1.6 7.6 4.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF2867 PF11066.3 CDJ65575.1 - 1.2 8.8 4.9 1.5 8.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) Peptidase_S15 PF02129.13 CDJ65575.1 - 1.4 8.3 7.7 1.7 7.9 5.3 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CD20 PF04103.10 CDJ65575.1 - 1.5 8.7 4.4 3.6 7.5 2.8 1.9 1 1 0 1 1 1 0 CD20-like family Serinc PF03348.10 CDJ65575.1 - 1.5 7.4 5.9 1.6 7.3 4.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.8 CDJ65575.1 - 2.4 7.9 22.6 3 7.6 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.4 CDJ65575.1 - 3.4 7.3 25.2 12 5.5 17.4 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA IncA PF04156.9 CDJ65575.1 - 3.6 7.1 19.8 3.7 7.1 13.1 1.5 1 1 0 1 1 1 0 IncA protein DUF4106 PF13388.1 CDJ65575.1 - 3.9 6.3 16.2 4 6.2 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF2512 PF10710.4 CDJ65575.1 - 4.2 6.8 6.7 2.3 7.6 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) Ctr PF04145.10 CDJ65575.1 - 4.5 7.3 7.6 1.7 8.6 3.3 1.6 1 1 1 2 2 2 0 Ctr copper transporter family BLVR PF06375.6 CDJ65575.1 - 5 6.9 11.5 2 8.2 0.2 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DUF2215 PF10225.4 CDJ65575.1 - 7.8 5.8 6.2 8.3 5.7 4.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF3770 PF12603.3 CDJ65577.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) SR-25 PF10500.4 CDJ65577.1 - 0.22 10.9 11.8 0.44 9.9 8.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ65577.1 - 2 7.7 6.1 3.5 6.9 4.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sporozoite_P67 PF05642.6 CDJ65578.1 - 1.9 6.2 17.0 2.3 5.9 11.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RCR PF12273.3 CDJ65580.1 - 0.015 15.8 0.0 0.024 15.1 0.0 1.4 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Mg_trans_NIPA PF05653.9 CDJ65581.1 - 3.2e-13 49.2 9.2 4.5e-08 32.4 0.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Pex2_Pex12 PF04757.9 CDJ65582.1 - 5.3e-18 65.2 13.2 1.6e-17 63.6 9.2 1.8 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 CDJ65582.1 - 0.0016 18.0 6.5 0.0029 17.2 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ65582.1 - 0.14 11.9 8.6 0.31 10.7 5.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CDJ65582.1 - 0.53 10.1 10.8 1.1 9.1 7.5 1.5 1 0 0 1 1 1 0 Ring finger domain UPF0081 PF03652.10 CDJ65583.1 - 2.7e-13 50.1 1.3 6.1e-09 36.0 0.0 2.7 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0081) AAA_23 PF13476.1 CDJ65584.1 - 9.1 6.5 9.6 35 4.6 5.3 2.3 2 0 0 2 2 2 0 AAA domain Nol1_Nop2_Fmu PF01189.12 CDJ65585.1 - 7.4e-07 28.8 2.0 0.00026 20.4 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family Med15 PF09606.5 CDJ65586.1 - 4.3 5.4 40.9 1.1 7.3 11.9 2.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3446 PF11928.3 CDJ65586.1 - 4.3 7.6 34.9 0.37 11.0 1.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3446) TFIIA PF03153.8 CDJ65586.1 - 8.6 6.1 21.9 1.2 8.9 5.1 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3752 PF12572.3 CDJ65587.1 - 1.5 8.9 23.2 6.6 6.8 10.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) MDFI PF15316.1 CDJ65588.1 - 0.0018 18.2 13.2 0.0018 18.2 9.1 4.1 3 1 0 3 3 3 1 MyoD family inhibitor Tic20 PF09685.5 CDJ65588.1 - 0.011 15.6 4.7 3.9 7.4 2.6 2.3 2 0 0 2 2 2 0 Tic20-like protein Mem_trans PF03547.13 CDJ65588.1 - 0.015 13.5 0.9 0.041 12.1 0.7 1.4 1 1 0 1 1 1 0 Membrane transport protein Ank PF00023.25 CDJ65588.1 - 0.019 14.7 0.5 0.079 12.8 0.3 2.0 1 0 0 1 1 1 0 Ankyrin repeat Fmp27_WPPW PF10359.4 CDJ65588.1 - 0.043 12.2 3.3 0.055 11.8 2.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ank_3 PF13606.1 CDJ65588.1 - 0.091 13.0 0.7 0.36 11.2 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat DUF1712 PF08217.6 CDJ65588.1 - 0.37 8.9 3.9 0.48 8.6 2.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Sporozoite_P67 PF05642.6 CDJ65588.1 - 3 5.5 8.8 3.8 5.2 6.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_viral_N PF00242.12 CDJ65588.1 - 3.4 6.5 17.3 5.4 5.9 12.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Rad60-SLD_2 PF13881.1 CDJ65589.1 - 0.00012 21.9 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Laminin_EGF PF00053.19 CDJ65589.1 - 0.86 9.5 5.3 1.9 8.4 3.6 1.5 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Ldh_1_C PF02866.13 CDJ65590.1 - 3e-21 75.9 0.1 3.4e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Mito_carr PF00153.22 CDJ65590.1 - 0.036 13.7 0.0 0.047 13.3 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial carrier protein DUF552 PF04472.7 CDJ65590.1 - 0.052 13.4 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF552) Glyco_hydro_4C PF11975.3 CDJ65590.1 - 0.09 12.5 0.1 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain tRNA-synt_2c PF01411.14 CDJ65591.1 - 2.9 6.0 10.7 1.4 7.1 6.2 1.3 1 1 0 1 1 1 0 tRNA synthetases class II (A) CDK2AP PF09806.4 CDJ65591.1 - 5.9 7.0 20.4 7.6 6.7 14.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2361 PF10153.4 CDJ65591.1 - 8.3 6.6 16.4 10 6.3 1.8 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) DUF966 PF06136.8 CDJ65591.1 - 8.9 5.6 18.7 10 5.3 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.9 CDJ65592.1 - 0.12 10.4 6.5 0.11 10.4 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop25 PF09805.4 CDJ65592.1 - 0.35 10.9 8.2 0.43 10.6 5.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2217 PF10265.4 CDJ65592.1 - 0.38 9.4 17.6 0.39 9.4 12.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FAM60A PF15396.1 CDJ65592.1 - 1.6 8.4 11.8 1.8 8.2 8.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF572 PF04502.8 CDJ65592.1 - 2.3 7.3 19.9 2.6 7.1 13.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.11 CDJ65592.1 - 3.8 7.3 11.9 4.1 7.2 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDJ65592.1 - 5 4.6 21.7 5.1 4.6 15.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF566 PF04484.7 CDJ65592.1 - 5 6.5 33.9 5.8 6.3 23.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) HSD3 PF15244.1 CDJ65592.1 - 5.9 6.0 15.0 5.9 6.0 10.4 1.1 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase DUF2052 PF09747.4 CDJ65592.1 - 6.1 6.7 11.1 7.2 6.5 7.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4647 PF15504.1 CDJ65592.1 - 6.3 5.5 13.3 6.3 5.5 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) NABP PF07990.7 CDJ65592.1 - 8.1 5.6 24.5 9.1 5.4 17.0 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Med15 PF09606.5 CDJ65593.1 - 0.0024 16.1 11.7 0.0027 16.0 8.1 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDJ65593.1 - 0.0065 16.5 0.3 0.011 15.8 0.2 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 CDJ65593.1 - 0.0094 15.3 0.9 0.013 14.8 0.6 1.2 1 0 0 1 1 1 1 Spt20 family FHIPEP PF00771.15 CDJ65593.1 - 0.034 12.4 0.0 0.045 12.0 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family Suf PF05843.9 CDJ65593.1 - 0.45 10.2 5.1 0.61 9.7 3.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) E_Pc_C PF06752.7 CDJ65593.1 - 0.66 9.4 11.9 0.96 8.9 8.2 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF3021 PF11457.3 CDJ65593.1 - 0.74 9.6 6.0 1.2 8.9 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Calici_MSP PF05752.6 CDJ65593.1 - 4.3 6.9 11.5 7 6.2 8.0 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein Phage_Gp23 PF10669.4 CDJ65593.1 - 4.7 7.3 9.1 31 4.6 4.6 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF4557 PF15101.1 CDJ65593.1 - 7.8 6.2 10.8 13 5.5 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Activator_LAG-3 PF11498.3 CDJ65593.1 - 8.8 4.9 27.3 12 4.4 18.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pyr_redox_dim PF02852.17 CDJ65594.1 - 1.4e-18 66.8 0.1 3.6e-18 65.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CDJ65594.1 - 3.4e-14 53.0 0.0 6.7e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDJ65594.1 - 1.2e-07 31.8 0.0 7.4e-07 29.2 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 CDJ65594.1 - 0.0041 16.2 0.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2722 PF10846.3 CDJ65594.1 - 0.0059 15.6 0.1 0.0059 15.6 0.1 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF2722) UDPG_MGDP_dh_N PF03721.9 CDJ65594.1 - 0.013 14.9 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Spt20 PF12090.3 CDJ65594.1 - 0.016 14.6 6.2 0.3 10.4 1.4 2.5 2 0 0 2 2 2 0 Spt20 family 3HCDH_N PF02737.13 CDJ65594.1 - 0.067 12.8 0.0 0.067 12.8 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KH_1 PF00013.24 CDJ65595.1 - 3.6e-07 29.7 0.0 4.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CDJ65595.1 - 0.00016 21.2 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 KH domain FAD_binding_3 PF01494.14 CDJ65598.1 - 3.5e-13 49.3 0.1 4.4e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CDJ65598.1 - 0.00094 19.1 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDJ65598.1 - 0.0018 17.2 0.2 0.0026 16.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Alpha_GJ PF03229.8 CDJ65598.1 - 0.0027 18.0 2.4 0.0042 17.4 1.7 1.2 1 0 0 1 1 1 1 Alphavirus glycoprotein J Thi4 PF01946.12 CDJ65598.1 - 0.025 13.6 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CDJ65598.1 - 0.027 14.3 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pex14_N PF04695.8 CDJ65598.1 - 0.036 14.1 6.9 0.064 13.3 4.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 CDJ65598.1 - 0.038 12.1 2.9 0.036 12.2 2.0 1.0 1 0 0 1 1 1 0 Menin FAD_binding_2 PF00890.19 CDJ65598.1 - 0.099 11.4 0.2 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Atrophin-1 PF03154.10 CDJ65598.1 - 0.81 7.7 12.3 0.86 7.6 8.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family BUD22 PF09073.5 CDJ65598.1 - 0.91 8.5 15.0 1.2 8.1 10.4 1.1 1 0 0 1 1 1 0 BUD22 POX PF07526.6 CDJ65598.1 - 1.7 8.8 8.3 2.4 8.3 5.7 1.1 1 0 0 1 1 1 0 Associated with HOX Macoilin PF09726.4 CDJ65598.1 - 6.9 4.8 24.4 8.4 4.5 16.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 CDJ65598.1 - 7.4 5.9 20.2 9.5 5.6 14.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1183 PF06682.7 CDJ65598.1 - 8.5 5.8 12.2 10 5.6 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Kei1 PF08552.6 CDJ65598.1 - 9.6 5.8 7.0 13 5.4 4.9 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_L12 PF00542.14 CDJ65599.1 - 2.3e-19 69.1 3.0 2.8e-19 68.8 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain TFIIF_alpha PF05793.7 CDJ65600.1 - 6.3 5.0 41.8 0.032 12.6 22.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SR-25 PF10500.4 CDJ65601.1 - 0.0049 16.3 19.9 0.0056 16.1 13.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein THRAP3_BCLAF1 PF15440.1 CDJ65601.1 - 0.025 13.2 10.8 0.026 13.1 7.5 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF4614 PF15391.1 CDJ65601.1 - 0.15 11.8 9.7 0.17 11.6 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Pex14_N PF04695.8 CDJ65601.1 - 0.43 10.6 11.3 0.57 10.2 7.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ETRAMP PF09716.5 CDJ65601.1 - 1.8 8.5 7.2 8.5 6.4 5.0 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2201_N PF13203.1 CDJ65601.1 - 4.7 6.2 17.2 5.4 6.0 11.9 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Apt1 PF10351.4 CDJ65601.1 - 5.7 5.6 6.1 6 5.6 4.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF966 PF06136.8 CDJ65601.1 - 6.3 6.1 13.9 6.8 5.9 9.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 CDJ65601.1 - 7.2 4.7 16.6 8.2 4.5 11.5 1.1 1 0 0 1 1 1 0 Transmembrane protein CDP-OH_P_transf PF01066.16 CDJ65602.1 - 6.1e-17 61.7 0.6 9.6e-17 61.1 0.4 1.3 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Phage_portal PF04860.7 CDJ65602.1 - 0.19 10.3 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein Sporozoite_P67 PF05642.6 CDJ65603.1 - 0.37 8.6 19.8 0.6 7.9 13.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BCAS2 PF05700.6 CDJ65604.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) AAA_2 PF07724.9 CDJ65605.1 - 6e-23 81.6 0.1 4.2e-22 78.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CDJ65605.1 - 6.4e-15 55.5 0.0 9.3e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDJ65605.1 - 1.2e-07 31.0 0.1 0.0026 16.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CDJ65605.1 - 4.6e-07 30.0 6.2 2.5e-05 24.3 0.0 3.6 2 2 1 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 CDJ65605.1 - 2.1e-05 24.3 0.8 0.12 12.0 0.0 3.2 3 1 0 3 3 3 2 Archaeal ATPase AAA_22 PF13401.1 CDJ65605.1 - 5.2e-05 23.4 2.9 0.3 11.2 0.0 3.9 2 2 2 4 4 4 2 AAA domain Sigma54_activat PF00158.21 CDJ65605.1 - 6.2e-05 22.5 0.0 0.00056 19.4 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 CDJ65605.1 - 9.7e-05 22.1 0.3 0.0021 17.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CDJ65605.1 - 0.00014 21.0 0.0 0.0011 18.0 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 CDJ65605.1 - 0.0011 19.7 0.1 0.0081 16.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CDJ65605.1 - 0.019 15.2 0.2 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CDJ65605.1 - 0.02 13.8 0.2 0.39 9.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Torsin PF06309.6 CDJ65605.1 - 0.035 14.0 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Torsin T2SE PF00437.15 CDJ65605.1 - 0.04 12.8 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 CDJ65605.1 - 0.049 13.0 0.0 0.17 11.2 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 CDJ65605.1 - 0.056 12.8 1.0 1.1 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain Bac_DnaA PF00308.13 CDJ65605.1 - 0.057 13.0 0.5 0.26 10.8 0.0 2.3 3 1 0 3 3 3 0 Bacterial dnaA protein DUF258 PF03193.11 CDJ65605.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.12 CDJ65605.1 - 0.12 12.1 1.2 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_33 PF13671.1 CDJ65605.1 - 0.26 11.1 2.4 1.4 8.8 0.0 3.0 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.22 CDJ65605.1 - 0.32 11.2 4.1 0.53 10.5 0.0 2.7 1 1 1 2 2 2 0 ABC transporter AAA_23 PF13476.1 CDJ65605.1 - 5 7.4 14.9 73 3.5 9.0 2.4 2 1 0 2 2 2 0 AAA domain DUF4140 PF13600.1 CDJ65605.1 - 8.7 6.8 10.9 0.28 11.6 2.5 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ClpB_D2-small PF10431.4 CDJ65606.1 - 6.7e-14 51.5 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.9 CDJ65606.1 - 3.6e-09 36.7 0.0 6.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Aminotran_5 PF00266.14 CDJ65609.1 - 3.1e-27 95.2 0.0 1.1e-26 93.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V HHH_6 PF14579.1 CDJ65609.1 - 0.0048 16.9 0.0 4.4 7.4 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif Prok-RING_1 PF14446.1 CDJ65610.1 - 8.7e-05 22.1 0.7 8.7e-05 22.1 0.5 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DUF1777 PF08648.7 CDJ65610.1 - 0.00062 19.5 21.8 0.00062 19.5 15.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) FYDLN_acid PF09538.5 CDJ65610.1 - 6 7.5 8.3 0.44 11.1 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Syja_N PF02383.13 CDJ65612.1 - 7.3e-43 146.5 0.0 1.4e-39 135.7 0.0 3.7 3 1 0 3 3 3 2 SacI homology domain Neur_chan_memb PF02932.11 CDJ65612.1 - 0.16 11.7 4.4 0.22 11.3 0.6 2.7 3 1 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 CDJ65612.1 - 3.3 5.7 54.9 0.44 8.6 12.4 3.5 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal PX PF00787.19 CDJ65613.1 - 1.6e-14 53.6 0.0 3.8e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 PX domain Ras PF00071.17 CDJ65614.1 - 1.8e-14 53.4 0.0 4.6e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CDJ65614.1 - 2e-08 34.7 0.0 4.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_33 PF13671.1 CDJ65614.1 - 0.023 14.5 0.0 0.089 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CDJ65614.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase CytochromB561_N PF09786.4 CDJ65617.1 - 4 5.7 20.5 6.5 5.0 14.2 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pkinase PF00069.20 CDJ65618.1 - 1.3e-33 116.2 0.0 1.4e-16 60.4 0.0 3.2 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65618.1 - 4e-06 26.0 11.6 0.0052 15.8 0.0 4.1 5 0 0 5 5 5 3 Protein tyrosine kinase DUF3458 PF11940.3 CDJ65621.1 - 9.4e-56 189.2 0.5 5e-36 124.3 1.3 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3458) Sec7 PF01369.15 CDJ65621.1 - 0.12 12.0 0.2 0.16 11.6 0.2 1.1 1 0 0 1 1 1 0 Sec7 domain zf-RING_2 PF13639.1 CDJ65622.1 - 0.0018 18.0 0.3 0.0018 18.0 0.2 2.7 3 1 0 3 3 3 1 Ring finger domain TctB PF07331.6 CDJ65622.1 - 0.021 14.4 0.9 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF966 PF06136.8 CDJ65622.1 - 0.095 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Suf PF05843.9 CDJ65623.1 - 2.8 7.5 7.1 3.7 7.1 4.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAP1 PF08601.5 CDJ65623.1 - 7.6 6.1 11.2 8.9 5.8 7.8 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.4 CDJ65623.1 - 8.6 5.0 6.6 10 4.8 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3662 PF12401.3 CDJ65624.1 - 0.0086 16.2 0.2 0.025 14.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2662) CD99L2 PF12301.3 CDJ65624.1 - 2.3 7.8 16.7 0.44 10.2 8.3 2.2 3 0 0 3 3 3 0 CD99 antigen like protein 2 Tim54 PF11711.3 CDJ65624.1 - 4.9 5.6 10.2 2.4 6.6 5.0 2.0 2 1 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2042 PF09743.4 CDJ65625.1 - 8.9e-11 41.6 0.3 1.1e-10 41.3 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) DUF1173 PF06666.6 CDJ65625.1 - 0.041 12.7 1.6 0.053 12.3 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Spt20 PF12090.3 CDJ65625.1 - 0.047 13.0 0.7 0.045 13.0 0.5 1.2 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.3 CDJ65625.1 - 0.12 11.5 9.3 0.14 11.3 6.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2489 PF10675.4 CDJ65625.1 - 0.23 11.1 7.6 0.33 10.6 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DivIC PF04977.10 CDJ65625.1 - 2.1 7.8 9.4 3.6 7.1 6.5 1.3 1 0 0 1 1 1 0 Septum formation initiator ODAM PF15424.1 CDJ65625.1 - 3.9 6.9 18.1 5.1 6.5 12.6 1.3 1 1 0 1 1 1 0 Odontogenic ameloblast-associated family Asp_protease_2 PF13650.1 CDJ65626.1 - 3.8e-11 43.3 0.0 9.5e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ65626.1 - 6.4e-09 35.5 0.1 2e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ65626.1 - 8.7e-07 28.7 0.0 6.2e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CDJ65626.1 - 5.9e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein RVP_2 PF08284.6 CDJ65626.1 - 6.6e-06 26.1 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ65626.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CDJ65626.1 - 9.5 6.3 10.9 0.91 9.5 1.8 2.6 2 0 0 2 2 2 0 Zinc knuckle MORN PF02493.15 CDJ65627.1 - 7.8e-13 47.3 8.5 4.8e-05 22.8 0.4 4.1 4 0 0 4 4 4 3 MORN repeat Ribosomal_L7Ae PF01248.21 CDJ65628.1 - 2.1e-24 84.8 0.1 2.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.1 CDJ65628.1 - 0.058 13.2 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase APP_Cu_bd PF12924.2 CDJ65628.1 - 0.062 13.8 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD ArsA_ATPase PF02374.10 CDJ65630.1 - 9.6e-13 47.8 0.9 1.5e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase SR-25 PF10500.4 CDJ65630.1 - 0.031 13.7 12.1 0.036 13.5 8.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 CDJ65630.1 - 8.1 6.7 9.6 15 5.8 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) FAM60A PF15396.1 CDJ65630.1 - 8.2 6.1 9.7 10 5.7 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDJ65631.1 - 0.00032 20.5 15.1 0.0044 16.8 9.4 2.1 2 0 0 2 2 2 1 DDHD domain CobT PF06213.7 CDJ65631.1 - 0.0029 16.8 7.6 0.0029 16.8 5.2 1.7 2 0 0 2 2 1 1 Cobalamin biosynthesis protein CobT NPR3 PF03666.8 CDJ65631.1 - 0.0063 15.1 13.2 0.0063 15.1 9.1 1.7 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Pox_Ag35 PF03286.9 CDJ65631.1 - 0.0083 15.6 10.3 0.0083 15.6 7.1 1.6 2 0 0 2 2 2 1 Pox virus Ag35 surface protein Tim54 PF11711.3 CDJ65631.1 - 0.043 12.3 15.4 0.38 9.3 8.2 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2201_N PF13203.1 CDJ65631.1 - 0.12 11.5 23.7 0.14 11.3 12.6 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF4220 PF13968.1 CDJ65631.1 - 0.14 11.2 9.3 0.086 11.9 2.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) CDC45 PF02724.9 CDJ65631.1 - 0.27 9.2 23.5 0.11 10.4 12.2 2.1 2 0 0 2 2 2 0 CDC45-like protein PAT1 PF09770.4 CDJ65631.1 - 0.36 9.0 63.8 0.44 8.7 33.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FLO_LFY PF01698.11 CDJ65631.1 - 0.43 9.3 19.5 0.58 8.9 11.1 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Hid1 PF12722.2 CDJ65631.1 - 0.58 7.7 23.4 0.021 12.5 11.6 1.8 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CDJ65631.1 - 1.1 8.1 8.6 0.32 9.9 3.2 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 CDJ65631.1 - 1.2 8.9 21.4 6 6.6 12.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 CDJ65631.1 - 1.3 8.4 39.3 4 6.8 23.8 2.2 2 0 0 2 2 2 0 Spore coat protein CotO SPX PF03105.14 CDJ65631.1 - 1.8 8.2 19.1 8.7 6.0 11.9 2.0 2 0 0 2 2 2 0 SPX domain FHIPEP PF00771.15 CDJ65631.1 - 1.8 6.7 16.1 0.46 8.7 6.6 2.3 2 0 0 2 2 2 0 FHIPEP family MRP-S31 PF15433.1 CDJ65631.1 - 2.2 7.6 29.0 13 5.1 16.7 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 PIH1 PF08190.7 CDJ65631.1 - 3 7.1 31.0 1.5 8.1 17.6 2.1 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Med15 PF09606.5 CDJ65631.1 - 3.1 5.8 91.4 0.67 8.0 10.7 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.1 CDJ65631.1 - 6 4.4 74.7 2.9 5.4 40.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF4045 PF13254.1 CDJ65631.1 - 6.2 5.9 20.4 1.4 8.1 11.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Ycf1 PF05758.7 CDJ65631.1 - 6.9 4.2 25.4 0.26 8.9 13.1 1.7 2 0 0 2 2 2 0 Ycf1 TFIIA PF03153.8 CDJ65631.1 - 7.2 6.3 49.1 5.4 6.8 3.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex16 PF08610.5 CDJ65631.1 - 7.3 5.4 24.9 3.7 6.4 13.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) DUF1510 PF07423.6 CDJ65631.1 - 9 5.5 31.6 1.4 8.2 17.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CDJ65631.1 - 9.3 6.0 30.7 1.4 8.7 16.9 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CDJ65632.1 - 3 5.9 33.8 5.1 5.1 23.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ65632.1 - 4 7.2 28.7 5.9 6.6 19.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RS4NT PF08071.7 CDJ65633.1 - 3.9e-20 71.3 8.2 1.5e-19 69.5 4.8 2.0 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 CDJ65633.1 - 5.8e-07 28.8 0.1 8.1e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 S4 domain Ribosomal_S4e PF00900.15 CDJ65633.1 - 0.00031 20.3 0.1 0.00065 19.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal family S4e PepX_C PF08530.5 CDJ65634.1 - 3.2e-14 53.3 0.5 5.5e-11 42.7 0.0 2.5 2 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 CDJ65634.1 - 3.5e-12 46.3 0.1 1.2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) SR-25 PF10500.4 CDJ65635.1 - 1.1e-05 24.9 18.8 1.1e-05 24.9 13.0 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ65635.1 - 0.00057 19.9 3.2 0.00057 19.9 2.2 3.9 4 0 0 4 4 3 1 Domain of unknown function (DUF755) Ycf1 PF05758.7 CDJ65635.1 - 0.0045 14.7 5.9 0.007 14.1 4.1 1.3 1 0 0 1 1 1 1 Ycf1 Sec62 PF03839.11 CDJ65635.1 - 0.071 12.5 5.6 0.15 11.4 3.9 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 BPL_N PF09825.4 CDJ65635.1 - 0.22 10.2 6.0 0.34 9.6 4.2 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal CobT PF06213.7 CDJ65635.1 - 0.46 9.5 12.3 0.83 8.7 8.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3446 PF11928.3 CDJ65635.1 - 0.77 9.9 30.0 0.1 12.8 5.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF2201_N PF13203.1 CDJ65635.1 - 0.78 8.8 17.3 1.3 8.0 12.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Peptidase_S49_N PF08496.5 CDJ65635.1 - 1.1 9.1 10.7 2.3 7.9 7.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Borrelia_P83 PF05262.6 CDJ65635.1 - 1.1 7.4 20.0 1.8 6.7 13.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein FLO_LFY PF01698.11 CDJ65635.1 - 1.1 7.9 18.7 2.2 7.0 12.2 1.8 2 0 0 2 2 2 0 Floricaula / Leafy protein SoxE PF06525.6 CDJ65635.1 - 1.3 8.2 6.7 1.1 8.5 0.3 2.2 2 0 0 2 2 2 0 Sulfocyanin (SoxE) DUF4407 PF14362.1 CDJ65635.1 - 1.4 7.7 14.0 3.8 6.3 9.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Suf PF05843.9 CDJ65635.1 - 1.6 8.4 21.3 0.024 14.3 9.8 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ65635.1 - 2 6.5 32.8 0.0055 15.0 15.1 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 GPCR_chapero_1 PF11904.3 CDJ65635.1 - 4 6.4 14.2 7.8 5.5 9.9 1.4 1 0 0 1 1 1 0 GPCR-chaperone Ubie_methyltran PF01209.13 CDJ65638.1 - 3.8e-33 114.5 0.0 2.2e-18 66.2 0.0 3.3 3 1 0 3 3 3 3 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CDJ65638.1 - 4.3e-13 49.5 0.4 4.6e-10 39.8 0.0 3.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ65638.1 - 2e-09 37.7 0.0 0.0015 18.8 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ65638.1 - 1.8e-08 34.0 0.0 0.00028 20.5 0.0 3.2 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ65638.1 - 1.2e-07 31.5 0.0 2.4e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ65638.1 - 2e-05 24.9 0.0 0.0029 18.0 0.0 3.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ65638.1 - 2.1e-05 25.0 0.5 0.00034 21.1 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ65638.1 - 3.4e-05 23.8 0.0 7.5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PAT1 PF09770.4 CDJ65638.1 - 0.027 12.7 10.4 0.03 12.5 7.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NAD_binding_4 PF07993.7 CDJ65638.1 - 0.041 12.7 0.3 0.053 12.4 0.2 1.1 1 0 0 1 1 1 0 Male sterility protein KR PF08659.5 CDJ65638.1 - 0.058 13.0 1.4 0.1 12.2 1.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 CDJ65638.1 - 0.092 12.6 0.9 0.15 11.9 0.6 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CDJ65638.1 - 0.19 10.5 1.1 0.25 10.2 0.8 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AF-4 PF05110.8 CDJ65638.1 - 0.23 9.2 10.4 0.36 8.6 7.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3446 PF11928.3 CDJ65638.1 - 0.24 11.5 11.9 0.71 10.0 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) RED_N PF07808.8 CDJ65638.1 - 7.8 5.6 11.7 11 5.1 8.1 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region NIF PF03031.13 CDJ65639.1 - 3.3e-20 72.3 0.0 5.7e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CDJ65639.1 - 0.0016 18.6 0.1 0.045 13.9 0.0 2.7 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Steroid_dh PF02544.11 CDJ65640.1 - 1.2e-32 112.7 7.7 1.7e-27 96.0 0.9 3.4 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase RskA PF10099.4 CDJ65640.1 - 0.11 12.2 1.2 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PEMT PF04191.8 CDJ65640.1 - 0.16 12.0 2.5 0.44 10.6 0.0 2.5 3 0 0 3 3 3 0 Phospholipid methyltransferase CactinC_cactus PF09732.4 CDJ65641.1 - 1.7e-51 172.9 7.7 1.7e-51 172.9 5.3 1.7 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 CDJ65641.1 - 7.3e-36 123.2 3.9 7.3e-36 123.2 2.7 2.9 2 1 0 2 2 2 1 Conserved mid region of cactin Ketoacyl-synt_C PF02801.17 CDJ65642.1 - 3.5e-27 94.6 0.2 4.2e-27 94.3 0.2 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain tRNA-synt_1 PF00133.17 CDJ65643.1 - 2e-28 98.8 1.1 4.3e-11 41.5 0.0 5.2 4 1 1 5 5 5 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CDJ65643.1 - 5.5e-20 71.3 0.0 1.7e-07 30.2 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CDJ65643.1 - 1.7e-11 44.1 0.0 4.4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 CDJ65643.1 - 1.5e-06 27.6 0.0 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.13 CDJ65643.1 - 0.28 9.8 0.0 0.5 8.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) RAB3GAP2_N PF14655.1 CDJ65643.1 - 1.3 7.9 2.7 2.2 7.1 0.6 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF155 PF02582.9 CDJ65645.1 - 8.8e-48 162.5 0.0 1.3e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BING4CT PF08149.6 CDJ65646.1 - 5.5e-32 109.1 0.0 1.5e-29 101.2 0.0 2.6 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 CDJ65646.1 - 1.6e-05 24.5 0.1 0.048 13.5 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Merozoite_SPAM PF07133.6 CDJ65646.1 - 0.26 11.1 3.9 0.44 10.4 2.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF3530 PF12048.3 CDJ65646.1 - 5.7 5.8 10.3 2.3 7.1 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Ion_trans PF00520.26 CDJ65647.1 - 8.1e-21 74.1 16.3 2.3e-13 49.8 1.0 2.6 2 1 0 2 2 2 2 Ion transport protein DUF788 PF05620.6 CDJ65647.1 - 0.17 11.6 6.7 8.5 6.2 2.3 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF3260 PF11658.3 CDJ65647.1 - 0.28 9.3 8.3 0.48 8.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) EphA2_TM PF14575.1 CDJ65647.1 - 0.58 10.5 2.5 11 6.4 0.1 3.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4199 PF13858.1 CDJ65647.1 - 1.5 8.7 14.3 4.2 7.2 2.3 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4199) FixQ PF05545.6 CDJ65647.1 - 3.2 7.4 7.4 6 6.5 0.4 3.7 2 1 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PAP_assoc PF03828.14 CDJ65649.1 - 0.0065 16.4 0.9 0.045 13.6 0.6 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase Dicty_REP PF05086.7 CDJ65649.1 - 0.92 7.1 0.6 3.4 5.3 0.4 1.9 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_60s PF00428.14 CDJ65650.1 - 0.026 14.9 31.9 0.089 13.2 8.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4614 PF15391.1 CDJ65650.1 - 0.032 13.9 12.1 0.049 13.3 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Pex14_N PF04695.8 CDJ65650.1 - 0.16 12.0 14.6 0.04 13.9 7.5 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec3_C PF09763.4 CDJ65650.1 - 0.32 9.0 4.9 0.34 8.9 3.4 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.4 CDJ65650.1 - 0.37 9.0 18.8 0.44 8.7 13.0 1.2 1 0 0 1 1 1 0 Transmembrane protein CoA_transf_3 PF02515.12 CDJ65650.1 - 0.64 9.2 9.9 0.093 11.9 0.4 2.1 2 0 0 2 2 2 0 CoA-transferase family III DUF572 PF04502.8 CDJ65650.1 - 0.87 8.7 6.2 0.99 8.5 4.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Secretin_N_2 PF07655.8 CDJ65650.1 - 1.2 9.5 30.6 2.2 8.7 21.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF2981 PF11200.3 CDJ65650.1 - 1.3 7.9 7.7 1.8 7.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2217 PF10265.4 CDJ65650.1 - 1.4 7.6 12.1 2 7.0 8.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4551 PF15087.1 CDJ65650.1 - 1.5 7.0 8.2 1.9 6.7 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DNA_pol_viral_N PF00242.12 CDJ65650.1 - 1.8 7.5 12.1 2.3 7.1 8.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF3827 PF12877.2 CDJ65650.1 - 6.3 4.7 10.7 7.6 4.5 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Golgin_A5 PF09787.4 CDJ65650.1 - 6.9 5.0 13.8 8.3 4.8 9.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 RAP1 PF07218.6 CDJ65650.1 - 7.1 4.5 23.9 8.3 4.3 16.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YibE_F PF07907.6 CDJ65651.1 - 0.0014 17.8 1.4 0.031 13.4 0.3 2.1 2 0 0 2 2 2 1 YibE/F-like protein DUF998 PF06197.8 CDJ65651.1 - 0.34 10.1 15.8 1.4 8.1 7.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) MgtE PF01769.11 CDJ65651.1 - 0.59 10.4 4.4 1.6 9.0 1.0 2.3 2 0 0 2 2 2 0 Divalent cation transporter Chorion_2 PF03964.10 CDJ65651.1 - 8.6 6.9 15.1 0.34 11.4 1.0 2.8 3 0 0 3 3 3 0 Chorion family 2 DUF4636 PF15468.1 CDJ65652.1 - 0.012 15.0 1.1 0.012 15.0 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4636) TFIIA PF03153.8 CDJ65653.1 - 1.7 8.4 12.2 1.8 8.3 8.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIG1 PF04548.11 CDJ65653.1 - 2.5 7.1 6.4 2.9 6.9 4.4 1.1 1 0 0 1 1 1 0 AIG1 family Med15 PF09606.5 CDJ65653.1 - 2.5 6.1 24.9 2.8 6.0 17.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ65653.1 - 5.1 5.2 21.0 4.9 5.2 14.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIF_alpha PF05793.7 CDJ65654.1 - 0.0057 15.0 3.1 0.0064 14.9 2.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pex16 PF08610.5 CDJ65654.1 - 0.27 10.1 8.9 0.31 10.0 6.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF2217 PF10265.4 CDJ65654.1 - 0.28 9.8 6.5 0.32 9.7 4.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Band_3_cyto PF07565.8 CDJ65654.1 - 0.32 10.4 6.6 0.32 10.4 4.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EcoRI_methylase PF13651.1 CDJ65654.1 - 0.37 9.8 2.8 0.47 9.4 2.0 1.0 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Draxin PF15550.1 CDJ65654.1 - 0.69 9.5 8.2 0.81 9.2 5.7 1.0 1 0 0 1 1 1 0 Draxin UPF0560 PF10577.4 CDJ65654.1 - 0.72 8.0 18.9 0.87 7.7 13.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.2 CDJ65654.1 - 0.85 7.2 11.1 0.92 7.0 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_DNAp_acc PF04929.7 CDJ65654.1 - 0.86 8.5 6.8 0.9 8.4 4.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Bud13 PF09736.4 CDJ65654.1 - 1 9.5 13.1 1.2 9.3 9.1 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Activator_LAG-3 PF11498.3 CDJ65654.1 - 1.4 7.5 37.9 2.1 6.9 26.3 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF966 PF06136.8 CDJ65654.1 - 1.4 8.2 12.6 1.6 8.0 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dicty_REP PF05086.7 CDJ65654.1 - 1.9 6.1 7.2 2.1 6.0 5.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4175 PF13779.1 CDJ65654.1 - 2 6.0 37.0 2.5 5.6 25.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PLRV_ORF5 PF01690.12 CDJ65654.1 - 2.1 7.4 14.1 2.2 7.3 9.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neur_chan_memb PF02932.11 CDJ65654.1 - 3.3 7.5 6.3 3.4 7.4 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NST1 PF13945.1 CDJ65654.1 - 4.1 7.4 16.6 5.2 7.0 11.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Herpes_env PF01673.13 CDJ65654.1 - 5.1 5.5 9.3 5.3 5.4 6.4 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF2149 PF09919.4 CDJ65654.1 - 5.9 7.0 6.0 8.3 6.5 4.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Peptidase_S64 PF08192.6 CDJ65654.1 - 7.2 4.7 9.8 8.3 4.6 6.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 LCD1 PF09798.4 CDJ65654.1 - 7.6 4.3 16.1 8.2 4.2 11.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein eIF-3_zeta PF05091.7 CDJ65654.1 - 9.1 4.7 15.0 11 4.5 10.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ARF7EP_C PF14949.1 CDJ65654.1 - 9.6 6.6 10.5 13 6.2 7.3 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Med15 PF09606.5 CDJ65656.1 - 0.0029 15.8 25.4 0.0029 15.8 17.6 2.0 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal AUX_IAA PF02309.11 CDJ65656.1 - 0.042 13.5 0.8 0.064 12.9 0.5 1.4 1 0 0 1 1 1 0 AUX/IAA family FimP PF09766.4 CDJ65656.1 - 0.6 9.1 16.1 0.81 8.6 11.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDJ65656.1 - 1.4 8.5 11.2 2.1 8.0 7.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ65656.1 - 4.6 6.5 9.6 6.9 5.9 6.7 1.2 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.8 CDJ65657.1 - 0.54 10.2 21.0 2.4 8.2 9.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDJ65657.1 - 0.73 7.9 43.7 0.053 11.7 1.5 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1764 PF08576.5 CDJ65657.1 - 8 7.3 17.6 21 5.9 9.4 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF106 PF01956.11 CDJ65657.1 - 8.3 5.9 5.8 78 2.7 4.3 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 OmpH PF03938.9 CDJ65657.1 - 9.8 6.0 35.3 8.2 6.3 2.0 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Sec23_BS PF08033.7 CDJ65658.1 - 1.7e-13 50.8 0.0 1.7e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CDJ65658.1 - 0.00015 21.3 0.0 0.00015 21.3 0.0 2.6 2 0 0 2 2 1 1 Gelsolin repeat Borrelia_P83 PF05262.6 CDJ65658.1 - 0.068 11.4 5.3 0.099 10.9 3.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF-3_zeta PF05091.7 CDJ65658.1 - 0.13 10.9 10.6 0.17 10.4 7.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF106 PF01956.11 CDJ65658.1 - 0.18 11.3 5.9 0.53 9.8 4.2 1.7 2 0 0 2 2 1 0 Integral membrane protein DUF106 FLO_LFY PF01698.11 CDJ65658.1 - 0.24 10.1 6.9 0.37 9.5 4.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 CDJ65658.1 - 0.27 11.0 6.1 0.21 11.3 3.1 1.6 2 0 0 2 2 1 0 Peptidase family S49 N-terminal Ribosomal_60s PF00428.14 CDJ65658.1 - 0.32 11.4 25.2 2.4 8.6 3.1 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein AIF_C PF14721.1 CDJ65658.1 - 0.47 10.7 4.9 1 9.6 3.4 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIH1 PF08190.7 CDJ65658.1 - 0.65 9.3 14.2 1.3 8.4 9.8 1.4 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Baculo_PP31 PF05311.6 CDJ65658.1 - 0.85 8.8 9.4 1.3 8.2 6.5 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Serinc PF03348.10 CDJ65658.1 - 1.4 7.5 6.0 2.1 6.9 4.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.15 CDJ65658.1 - 1.6 6.7 5.9 2.3 6.1 4.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PBP_sp32 PF07222.7 CDJ65658.1 - 2.1 7.4 12.9 3.2 6.8 8.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3464 PF11947.3 CDJ65658.1 - 3.9 6.9 7.4 8.1 5.8 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) FimP PF09766.4 CDJ65658.1 - 4.1 6.3 21.1 0.42 9.6 11.5 1.5 2 0 0 2 2 2 0 Fms-interacting protein MDFI PF15316.1 CDJ65658.1 - 4.4 7.2 5.9 7.9 6.4 4.1 1.4 1 0 0 1 1 1 0 MyoD family inhibitor DUF3043 PF11241.3 CDJ65658.1 - 7 6.2 12.9 17 4.9 8.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) zf-DHHC PF01529.15 CDJ65658.1 - 9.2 5.6 7.0 18 4.6 4.9 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Sec23_trunk PF04811.10 CDJ65659.1 - 1.1e-48 165.6 1.0 5.1e-39 134.0 0.3 3.1 2 1 0 2 2 2 2 Sec23/Sec24 trunk domain DJ-1_PfpI PF01965.19 CDJ65659.1 - 0.0069 15.8 0.1 0.0069 15.8 0.1 2.1 2 0 0 2 2 2 1 DJ-1/PfpI family Spt20 PF12090.3 CDJ65659.1 - 0.057 12.7 0.4 0.085 12.2 0.3 1.2 1 0 0 1 1 1 0 Spt20 family FHIPEP PF00771.15 CDJ65659.1 - 0.061 11.6 0.2 0.089 11.1 0.1 1.2 1 0 0 1 1 1 0 FHIPEP family TORC_M PF12885.2 CDJ65659.1 - 0.1 12.3 0.6 0.18 11.5 0.4 1.3 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Claudin_2 PF13903.1 CDJ65659.1 - 0.1 12.2 3.2 0.35 10.5 0.2 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DivIC PF04977.10 CDJ65659.1 - 8.1 6.0 11.0 6.3 6.3 5.2 2.1 2 0 0 2 2 2 0 Septum formation initiator ChAPs PF09295.5 CDJ65660.1 - 3.3e-18 65.6 0.0 5.5e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF2397 PF09660.5 CDJ65661.1 - 2 6.9 13.8 1.1 7.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) CRISPR_Cse2 PF09485.5 CDJ65661.1 - 3.4 7.7 12.0 7.6 6.5 0.3 2.1 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) SR-25 PF10500.4 CDJ65662.1 - 6.7e-05 22.4 8.4 6.7e-05 22.4 5.8 15.9 14 3 2 16 16 16 7 Nuclear RNA-splicing-associated protein PHD_2 PF13831.1 CDJ65662.1 - 0.0015 17.7 44.4 0.037 13.3 0.4 7.1 8 0 0 8 8 8 4 PHD-finger AA_kinase PF00696.23 CDJ65663.1 - 5.9e-20 71.8 0.1 4.2e-19 69.0 0.0 3.4 3 1 0 3 3 3 2 Amino acid kinase family Ribosomal_60s PF00428.14 CDJ65663.1 - 7e-05 23.1 11.5 7e-05 23.1 8.0 4.4 3 1 1 4 4 4 1 60s Acidic ribosomal protein RAP1 PF07218.6 CDJ65664.1 - 0.32 9.0 8.1 0.45 8.5 5.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.14 CDJ65664.1 - 1.1 9.7 15.0 8.9 6.7 0.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mitofilin PF09731.4 CDJ65665.1 - 0.59 8.7 20.4 0.74 8.3 14.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3337 PF11816.3 CDJ65665.1 - 1.2 8.4 11.0 1.4 8.2 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) TFIIA PF03153.8 CDJ65665.1 - 1.2 8.9 27.3 2.1 8.1 18.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hex_IIIa PF02455.11 CDJ65665.1 - 2.7 6.5 14.0 3.2 6.3 9.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Parvo_coat PF00740.13 CDJ65665.1 - 4.8 6.0 10.6 5.6 5.7 7.3 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Utp14 PF04615.8 CDJ65665.1 - 6.5 4.7 13.5 8 4.4 9.3 1.0 1 0 0 1 1 1 0 Utp14 protein CDC27 PF09507.5 CDJ65666.1 - 0.018 14.2 39.8 0.023 13.9 27.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.4 CDJ65666.1 - 1.2 7.2 70.9 1.6 6.8 49.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDJ65666.1 - 2.6 7.8 31.2 3.9 7.2 21.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 CDJ65666.1 - 7.1 4.9 59.8 8.9 4.6 41.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TMEM51 PF15345.1 CDJ65668.1 - 1.3e-06 28.3 0.2 1.6e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 DUF3357 PF11837.3 CDJ65668.1 - 0.012 15.4 0.4 0.021 14.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) LRR19-TM PF15176.1 CDJ65668.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2909 PF11137.3 CDJ65668.1 - 0.056 13.1 0.4 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Acyltransferase PF01553.16 CDJ65669.1 - 1.1e-05 24.8 0.0 2.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase FA_desaturase PF00487.19 CDJ65669.1 - 0.65 9.3 3.2 1.2 8.5 2.2 1.5 1 0 0 1 1 1 0 Fatty acid desaturase tRNA-synt_1 PF00133.17 CDJ65670.1 - 3.8e-43 147.4 0.4 3.3e-17 61.7 0.0 6.6 5 1 1 6 6 6 6 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CDJ65670.1 - 1.2e-09 38.0 0.0 2.1e-07 30.8 0.0 2.5 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CDJ65670.1 - 1.7e-05 23.7 0.0 0.14 10.8 0.0 3.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) NMD3 PF04981.8 CDJ65672.1 - 2.4e-33 115.2 0.0 2.4e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 NMD3 family CENP-R PF06729.7 CDJ65672.1 - 1.2 8.7 11.6 2.2 7.9 0.5 2.7 3 0 0 3 3 3 0 Kinetochore component, CENP-R SPX PF03105.14 CDJ65672.1 - 1.9 8.2 11.7 5.8 6.6 4.2 2.2 2 0 0 2 2 2 0 SPX domain vATP-synt_AC39 PF01992.11 CDJ65674.1 - 8.2e-50 169.8 0.0 1.6e-49 168.8 0.0 1.4 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit RAB3GAP2_N PF14655.1 CDJ65674.1 - 0.012 14.5 0.1 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Activator_LAG-3 PF11498.3 CDJ65674.1 - 0.26 9.9 8.0 0.12 11.0 3.2 1.8 2 0 0 2 2 2 0 Transcriptional activator LAG-3 POP1 PF06978.6 CDJ65675.1 - 8.4 6.0 18.3 1.2 8.7 7.6 2.4 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 DUF615 PF04751.9 CDJ65676.1 - 0.055 13.1 0.1 0.058 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Tcf25 PF04910.9 CDJ65676.1 - 0.078 11.9 0.3 0.079 11.8 0.2 1.0 1 0 0 1 1 1 0 Transcriptional repressor TCF25 PKK PF12474.3 CDJ65676.1 - 0.1 12.2 0.3 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Polo kinase kinase AF-4 PF05110.8 CDJ65676.1 - 0.15 9.9 9.1 0.13 10.0 6.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Myco_19_kDa PF05481.7 CDJ65676.1 - 0.5 10.1 3.4 0.63 9.8 2.4 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen DUF755 PF05501.6 CDJ65676.1 - 3.7 7.6 18.3 4.4 7.3 12.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Trehalose_PPase PF02358.11 CDJ65677.1 - 4.6 6.0 5.7 1.5 7.7 0.1 2.5 2 1 1 3 3 3 0 Trehalose-phosphatase Macoilin PF09726.4 CDJ65677.1 - 5.5 5.1 11.2 6.5 4.9 7.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1966 PF09260.6 CDJ65677.1 - 7.4 6.7 7.3 12 6.0 1.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1966) MFS_1 PF07690.11 CDJ65678.1 - 2e-35 122.1 32.3 1.4e-30 106.2 15.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDJ65678.1 - 7e-06 24.8 8.6 7e-06 24.8 6.0 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 CDJ65678.1 - 1.2e-05 23.9 14.7 0.0018 16.8 2.9 2.9 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 CDJ65678.1 - 0.0018 17.9 0.0 0.15 11.8 0.0 2.9 2 0 0 2 2 2 1 MFS_1 like family DUF3169 PF11368.3 CDJ65678.1 - 0.02 14.0 2.1 8.6 5.4 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) TSP9 PF11493.3 CDJ65679.1 - 0.16 12.5 4.9 0.23 12.0 0.0 2.9 2 1 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Cation_efflux PF01545.16 CDJ65679.1 - 0.2 10.7 1.9 0.35 9.8 1.3 1.4 1 0 0 1 1 1 0 Cation efflux family SET PF00856.23 CDJ65680.1 - 1e-10 42.1 1.5 8.6e-10 39.1 0.0 2.7 3 0 0 3 3 3 1 SET domain Tom37_C PF11801.3 CDJ65680.1 - 0.055 13.3 5.3 0.12 12.2 3.7 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF4175 PF13779.1 CDJ65680.1 - 1 6.9 19.9 1.3 6.6 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SAE2 PF08573.5 CDJ65680.1 - 1.9 9.2 9.2 5 7.9 0.0 2.8 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus TPR_12 PF13424.1 CDJ65681.1 - 1.6e-06 27.9 25.7 0.0062 16.4 0.2 7.5 6 3 0 6 6 6 2 Tetratricopeptide repeat RPN7 PF10602.4 CDJ65681.1 - 6.1e-06 25.7 1.4 0.012 14.9 0.1 3.7 3 1 0 3 3 3 2 26S proteasome subunit RPN7 TPR_8 PF13181.1 CDJ65681.1 - 0.00048 19.7 11.9 0.34 10.8 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 CDJ65681.1 - 0.00081 19.2 0.7 1.4 9.0 0.0 4.9 5 0 0 5 5 5 1 PPR repeat TPR_16 PF13432.1 CDJ65681.1 - 0.0019 18.7 0.2 0.0019 18.7 0.1 9.3 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ65681.1 - 0.0055 16.4 17.5 2.1 8.3 0.0 8.1 7 0 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CDJ65681.1 - 0.0062 16.3 16.0 3.2 7.5 0.0 6.7 7 1 0 7 7 7 2 Mad3/BUB1 homology region 1 DUF718 PF05336.8 CDJ65681.1 - 0.016 15.0 2.0 8.6 6.2 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF718) Aft1_HRA PF11786.3 CDJ65681.1 - 0.029 14.6 0.4 0.063 13.5 0.3 1.5 1 0 0 1 1 1 0 Aft1 HRA domain TPR_2 PF07719.12 CDJ65681.1 - 0.15 12.0 35.2 0.54 10.3 0.1 10.0 12 0 0 12 12 12 0 Tetratricopeptide repeat PCEMA1 PF07418.6 CDJ65681.1 - 0.31 10.3 2.0 0.63 9.3 1.4 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Ras PF00071.17 CDJ65682.1 - 1e-43 148.5 0.0 1.2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ65682.1 - 6.7e-12 45.9 0.0 1.5e-11 44.7 0.0 1.6 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CDJ65682.1 - 5.2e-10 38.8 0.0 7.1e-10 38.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDJ65682.1 - 0.00049 19.2 0.0 0.00066 18.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.10 CDJ65682.1 - 0.005 16.5 0.8 0.15 11.7 0.1 2.2 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 CDJ65682.1 - 0.032 14.4 0.3 0.35 11.0 0.1 2.3 1 1 1 2 2 2 0 RNA helicase AAA_22 PF13401.1 CDJ65682.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CDJ65682.1 - 0.073 12.2 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CDJ65682.1 - 0.075 12.9 0.1 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.17 CDJ65682.1 - 0.084 11.7 0.1 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.13 CDJ65682.1 - 0.09 11.7 0.1 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_16 PF13191.1 CDJ65682.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 CDJ65682.1 - 0.1 12.3 0.5 0.32 10.7 0.1 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CDJ65682.1 - 0.14 11.8 0.2 0.27 10.8 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 CDJ65682.1 - 0.14 11.5 0.1 0.97 8.8 0.1 2.4 1 1 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 CDJ65682.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 CDJ65682.1 - 0.15 11.9 0.4 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain MACPF PF01823.14 CDJ65683.1 - 0.038 13.6 5.7 0.092 12.4 3.9 1.6 1 0 0 1 1 1 0 MAC/Perforin domain PAN_1 PF00024.21 CDJ65684.1 - 8.9e-64 211.2 87.0 8.8e-09 35.0 1.1 11.2 7 3 4 11 11 11 11 PAN domain PAN_4 PF14295.1 CDJ65684.1 - 6.7e-51 169.8 69.1 6.5e-08 32.1 0.4 11.8 11 0 0 11 11 11 11 PAN domain PAN_3 PF08277.7 CDJ65684.1 - 2.6e-06 26.9 58.9 0.051 13.1 0.1 11.4 11 0 0 11 11 11 7 PAN-like domain PAN_2 PF08276.6 CDJ65684.1 - 0.0012 18.6 82.0 0.0035 17.1 1.3 11.4 11 1 0 11 11 11 7 PAN-like domain RAP PF08373.5 CDJ65686.1 - 0.00038 20.1 0.0 0.00094 18.9 0.0 1.6 1 0 0 1 1 1 1 RAP domain DSPc PF00782.15 CDJ65687.1 - 0.22 11.1 0.2 0.47 10.0 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Pkinase PF00069.20 CDJ65688.1 - 1.6e-42 145.4 0.0 2.2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65688.1 - 2.8e-24 85.6 0.0 3.6e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.1 CDJ65688.1 - 0.00027 20.5 0.0 0.0011 18.6 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 CDJ65688.1 - 0.00053 19.0 0.2 0.0014 17.7 0.1 1.7 1 0 0 1 1 1 1 EF hand APH PF01636.18 CDJ65688.1 - 0.00098 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_5 PF13202.1 CDJ65688.1 - 0.0024 17.1 0.1 0.0055 16.0 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CDJ65688.1 - 0.0088 16.1 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Kdo PF06293.9 CDJ65688.1 - 0.036 13.1 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CDJ65688.1 - 0.059 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-DHHC PF01529.15 CDJ65689.1 - 2.8e-06 26.8 3.4 3.3e-06 26.5 2.3 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase NfeD PF01957.13 CDJ65689.1 - 0.29 11.2 2.2 0.44 10.6 1.5 1.3 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF3675 PF12428.3 CDJ65690.1 - 0.11 12.6 0.9 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) RCC1 PF00415.13 CDJ65691.1 - 6.3e-06 26.3 0.4 0.029 14.5 0.0 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat zf-RanBP PF00641.13 CDJ65691.1 - 0.0028 16.7 8.3 0.005 15.9 5.8 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RCC1_2 PF13540.1 CDJ65691.1 - 0.026 14.1 2.1 0.026 14.1 1.4 2.0 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat AAA_23 PF13476.1 CDJ65691.1 - 0.76 10.0 6.4 3.3 7.9 4.7 1.8 1 1 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDJ65691.1 - 7.2 4.7 35.6 12 3.9 24.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RCC1 PF00415.13 CDJ65692.1 - 1.1e-21 76.7 11.7 4.4e-07 29.9 0.5 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ65692.1 - 1.2e-09 37.4 18.5 1.3e-07 31.0 6.4 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat DUF4349 PF14257.1 CDJ65692.1 - 0.18 11.0 4.8 0.21 10.7 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4139 PF13598.1 CDJ65692.1 - 0.63 9.2 5.0 0.83 8.8 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) T2SM_b PF10741.4 CDJ65692.1 - 3 7.5 7.1 4.6 6.8 4.9 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Caldesmon PF02029.10 CDJ65693.1 - 0.093 11.1 33.4 0.11 10.8 23.1 1.1 1 0 0 1 1 1 0 Caldesmon MIP-T3 PF10243.4 CDJ65693.1 - 0.16 10.4 47.4 0.19 10.1 32.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 CDJ65693.1 - 0.38 8.3 40.6 0.49 8.0 28.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.8 CDJ65693.1 - 6 4.8 50.6 8.4 4.4 35.1 1.2 1 0 0 1 1 1 0 Utp14 protein DUF3123 PF11321.3 CDJ65693.1 - 9.5 6.5 12.6 19 5.5 8.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) BBP1_C PF15272.1 CDJ65694.1 - 0.069 12.7 0.1 0.069 12.7 0.1 2.8 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal COQ7 PF03232.8 CDJ65694.1 - 0.13 11.7 1.5 0.32 10.4 0.1 1.9 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 DUF605 PF04652.11 CDJ65694.1 - 1.3 8.3 28.3 1.6 8.0 19.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF3138 PF11336.3 CDJ65694.1 - 1.8 6.6 17.1 0.15 10.2 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4638 PF15472.1 CDJ65695.1 - 0.17 11.4 13.3 0.19 11.3 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SARG PF15385.1 CDJ65695.1 - 0.18 11.1 12.3 0.18 11.1 8.5 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein DegT_DnrJ_EryC1 PF01041.12 CDJ65695.1 - 0.36 9.8 4.8 0.4 9.6 3.4 1.0 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3987 PF13148.1 CDJ65695.1 - 0.43 9.1 8.9 0.5 8.8 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4175 PF13779.1 CDJ65695.1 - 0.76 7.4 19.9 0.77 7.3 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Synaphin PF05835.7 CDJ65695.1 - 1.3 9.1 14.5 1.8 8.7 10.1 1.2 1 0 0 1 1 1 0 Synaphin protein EIIBC-GUT_N PF03612.9 CDJ65695.1 - 1.7 8.2 4.6 1.8 8.1 3.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Nuc_deoxyrib_tr PF05014.10 CDJ65695.1 - 1.8 8.4 3.8 2.4 8.0 2.6 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase DUF1764 PF08576.5 CDJ65695.1 - 1.9 9.3 10.7 2.3 9.0 7.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SPX PF03105.14 CDJ65695.1 - 2 8.1 11.5 2.3 7.9 8.0 1.1 1 0 0 1 1 1 0 SPX domain Adeno_VII PF03228.9 CDJ65695.1 - 2.3 8.8 8.8 2.8 8.5 6.1 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII Ctr PF04145.10 CDJ65695.1 - 2.3 8.2 6.2 2.9 7.9 4.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Activator_LAG-3 PF11498.3 CDJ65695.1 - 2.3 6.8 29.3 2.5 6.7 20.3 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Neur_chan_memb PF02932.11 CDJ65695.1 - 3.9 7.2 7.0 4.2 7.1 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.7 CDJ65695.1 - 4.7 5.7 13.0 4.8 5.6 9.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TMEM51 PF15345.1 CDJ65695.1 - 5.3 6.6 12.0 5.9 6.5 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 APG6 PF04111.7 CDJ65695.1 - 6.4 5.7 13.5 6.7 5.6 9.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Med19 PF10278.4 CDJ65695.1 - 6.6 6.3 14.1 7.1 6.2 9.8 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_U57 PF05582.7 CDJ65695.1 - 7.4 5.4 8.6 8.2 5.2 5.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF3373 PF11853.3 CDJ65695.1 - 8.9 4.7 8.2 10 4.5 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DDHD PF02862.12 CDJ65695.1 - 9.8 5.9 9.9 10 5.8 6.9 1.0 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 CDJ65695.1 - 10 4.2 21.3 10 4.1 14.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF883 PF05957.8 CDJ65696.1 - 0.04 14.2 0.4 0.069 13.5 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TMEM51 PF15345.1 CDJ65696.1 - 0.053 13.2 5.2 0.025 14.2 1.8 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 TPR_16 PF13432.1 CDJ65698.1 - 0.18 12.4 4.6 1.5 9.5 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat HTH_1 PF00126.22 CDJ65698.1 - 0.24 11.1 1.2 1.7 8.4 0.0 2.5 2 1 1 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family Med15 PF09606.5 CDJ65699.1 - 0.017 13.3 112.2 0.023 12.9 77.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cpn60_TCP1 PF00118.19 CDJ65700.1 - 1.8e-85 287.3 0.4 1.8e-85 287.3 0.3 1.5 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family Med15 PF09606.5 CDJ65700.1 - 0.56 8.3 38.0 0.74 7.9 26.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_27 PF13514.1 CDJ65700.1 - 6.3 4.3 22.1 10 3.6 15.3 1.2 1 0 0 1 1 1 0 AAA domain DUF3894 PF13033.1 CDJ65700.1 - 6.6 6.8 5.9 20 5.2 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3894) SR-25 PF10500.4 CDJ65701.1 - 7.4e-06 25.5 7.5 7.4e-06 25.5 5.2 4.8 3 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein DNA_pol3_a_NII PF11490.3 CDJ65701.1 - 0.005 16.4 3.4 0.005 16.4 2.3 5.1 5 0 0 5 5 5 1 DNA polymerase III polC-type N-terminus II Nop53 PF07767.6 CDJ65701.1 - 0.007 15.3 5.3 0.007 15.3 3.7 4.0 4 1 0 4 4 4 1 Nop53 (60S ribosomal biogenesis) RAB3GAP2_N PF14655.1 CDJ65701.1 - 1.1 8.1 22.9 3 6.7 2.8 3.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-DHHC PF01529.15 CDJ65701.1 - 5 6.4 5.3 16 4.8 0.1 3.0 3 0 0 3 3 3 0 DHHC palmitoyltransferase COX14 PF14880.1 CDJ65702.1 - 8.8e-06 25.2 0.4 1.6e-05 24.4 0.3 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c assembly SR-25 PF10500.4 CDJ65702.1 - 0.14 11.5 5.1 0.17 11.3 3.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Adaptin_N PF01602.15 CDJ65703.1 - 1.6e-38 132.3 0.0 2.4e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CDJ65703.1 - 1.9e-11 43.9 0.0 8.4e-09 35.4 0.0 2.9 2 1 0 2 2 2 2 Coatomer gamma subunit appendage platform subdomain SR-25 PF10500.4 CDJ65703.1 - 0.074 12.5 58.9 0.023 14.2 9.2 4.1 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein HEAT PF02985.17 CDJ65703.1 - 3.5 7.9 19.8 2.2 8.6 0.1 6.5 5 1 0 5 5 5 0 HEAT repeat DUF1042 PF06294.6 CDJ65705.1 - 1.6e-25 89.5 0.0 3e-25 88.6 0.0 1.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CDJ65705.1 - 6.7e-16 57.7 0.0 1e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain DUF3972 PF13118.1 CDJ65705.1 - 0.0038 17.3 5.4 0.0098 15.9 3.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3972) CH PF00307.26 CDJ65705.1 - 0.0048 16.9 0.0 0.011 15.8 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain HOOK PF05622.7 CDJ65705.1 - 0.04 11.7 4.8 0.12 10.1 0.0 2.5 1 1 2 3 3 3 0 HOOK protein M60-like PF13402.1 CDJ65705.1 - 0.081 11.8 0.1 0.17 10.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase M60-like family Pex14_N PF04695.8 CDJ65706.1 - 0.29 11.1 16.5 0.5 10.4 11.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CDJ65706.1 - 0.78 7.9 35.4 0.93 7.6 24.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CDJ65706.1 - 0.91 8.8 18.9 1.4 8.2 13.1 1.4 1 0 0 1 1 1 0 Vta1 like DUF4175 PF13779.1 CDJ65706.1 - 7.8 4.0 42.4 9.8 3.7 29.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ndc1_Nup PF09531.5 CDJ65706.1 - 9.3 4.5 12.2 0.85 7.9 4.8 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup THRAP3_BCLAF1 PF15440.1 CDJ65707.1 - 0.33 9.5 18.7 0.45 9.1 13.0 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family SOBP PF15279.1 CDJ65707.1 - 5.1 7.3 19.4 6.6 7.0 13.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein cEGF PF12662.2 CDJ65708.1 - 6.1e-07 28.9 42.4 0.025 14.1 2.5 5.7 6 0 0 6 6 6 4 Complement Clr-like EGF-like EGF PF00008.22 CDJ65708.1 - 1.6e-05 24.7 50.3 0.00046 20.0 4.0 6.0 5 0 0 5 5 5 4 EGF-like domain Daxx PF03344.10 CDJ65708.1 - 0.0024 16.4 17.4 0.0043 15.6 12.1 1.4 1 0 0 1 1 1 1 Daxx Family EGF_3 PF12947.2 CDJ65708.1 - 0.0045 16.9 1.7 0.0045 16.9 1.2 5.8 5 0 0 5 5 5 3 EGF domain FXa_inhibition PF14670.1 CDJ65708.1 - 0.0063 16.6 5.0 0.0063 16.6 3.5 7.4 5 1 2 7 7 6 3 Coagulation Factor Xa inhibitory site Ycf1 PF05758.7 CDJ65708.1 - 0.097 10.3 12.7 0.12 10.0 8.8 1.0 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 CDJ65708.1 - 0.84 8.2 15.2 1.2 7.7 10.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CDJ65708.1 - 0.88 7.1 22.8 1.7 6.2 15.8 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 CDJ65708.1 - 2.1 7.3 21.0 3.3 6.7 14.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TFIIA PF03153.8 CDJ65708.1 - 2.3 8.0 35.2 4.7 6.9 24.4 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Shadoo PF14999.1 CDJ65708.1 - 2.3 8.0 34.1 0.28 11.0 0.4 4.8 4 0 0 4 4 4 0 Shadow of prion protein, neuroprotective Med15 PF09606.5 CDJ65708.1 - 3.7 5.6 62.5 7.1 4.6 43.3 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Asp-B-Hydro_N PF05279.6 CDJ65708.1 - 5.5 6.7 18.3 7.9 6.2 12.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region cEGF PF12662.2 CDJ65709.1 - 0.034 13.7 25.6 0.09 12.4 0.2 5.7 5 0 0 5 5 5 0 Complement Clr-like EGF-like EGF_3 PF12947.2 CDJ65709.1 - 0.17 11.8 47.7 0.012 15.5 4.0 5.7 5 0 0 5 5 5 0 EGF domain FXa_inhibition PF14670.1 CDJ65709.1 - 2 8.5 56.9 0.32 11.1 1.5 6.1 5 1 0 5 5 5 0 Coagulation Factor Xa inhibitory site DUF2217 PF10265.4 CDJ65710.1 - 0.6 8.8 4.9 0.7 8.5 3.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Phage_GPD PF05954.6 CDJ65710.1 - 1.3 8.1 7.6 1.5 7.9 5.3 1.0 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) ASFV_J13L PF05568.6 CDJ65710.1 - 1.3 8.5 11.8 1.5 8.3 8.2 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein CDC27 PF09507.5 CDJ65710.1 - 2.6 7.1 10.9 3.1 6.9 7.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 CDJ65710.1 - 2.7 7.7 10.6 3.1 7.5 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 CDJ65710.1 - 4.2 6.7 13.5 4.7 6.6 9.0 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Atrophin-1 PF03154.10 CDJ65710.1 - 5.4 5.0 17.5 6.3 4.7 12.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF2232 PF09991.4 CDJ65712.1 - 5.8 5.8 5.1 20 4.0 0.4 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Med15 PF09606.5 CDJ65713.1 - 0.0012 17.1 33.9 0.0012 17.1 23.5 6.7 5 2 1 6 6 6 2 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDJ65713.1 - 0.003 16.4 12.6 0.003 16.4 8.8 14.7 11 3 2 15 15 15 2 BAF1 / ABF1 chromatin reorganising factor 2OG-FeII_Oxy_2 PF13532.1 CDJ65714.1 - 2.6e-23 82.8 3.8 2.6e-23 82.8 2.6 4.8 4 1 1 5 5 5 1 2OG-Fe(II) oxygenase superfamily RCC1 PF00415.13 CDJ65715.1 - 1.8e-16 60.0 13.0 1e-07 32.0 0.1 4.7 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Med15 PF09606.5 CDJ65715.1 - 2e-06 26.3 65.6 2e-06 26.3 45.5 6.6 6 1 0 7 7 7 3 ARC105 or Med15 subunit of Mediator complex non-fungal RNA_pol_Rpb1_5 PF04998.12 CDJ65715.1 - 0.0022 17.3 8.8 14 4.8 0.0 3.0 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 5 EF_TS PF00889.14 CDJ65717.1 - 6.4e-25 87.7 20.1 7e-22 77.8 2.9 3.5 3 1 0 3 3 3 2 Elongation factor TS UBA PF00627.26 CDJ65717.1 - 0.0083 15.9 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-C3HC PF07967.8 CDJ65717.1 - 0.024 14.4 0.4 0.061 13.0 0.3 1.7 1 0 0 1 1 1 0 C3HC zinc finger-like zf-DHHC PF01529.15 CDJ65717.1 - 0.052 12.9 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase IncA PF04156.9 CDJ65718.1 - 3.2e-06 26.8 3.9 3.4e-06 26.7 2.7 1.1 1 0 0 1 1 1 1 IncA protein Spt20 PF12090.3 CDJ65718.1 - 0.036 13.4 1.5 0.033 13.5 1.0 1.1 1 0 0 1 1 1 0 Spt20 family DUF212 PF02681.9 CDJ65718.1 - 0.064 12.9 1.6 0.083 12.6 1.1 1.1 1 0 0 1 1 1 0 Divergent PAP2 family RAB3GAP2_N PF14655.1 CDJ65718.1 - 0.1 11.6 3.9 0.11 11.4 2.7 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ERF PF04404.7 CDJ65718.1 - 0.19 11.2 5.4 0.21 11.0 3.7 1.2 1 0 0 1 1 1 0 ERF superfamily DUF457 PF04307.9 CDJ65718.1 - 0.29 10.4 2.3 0.36 10.1 1.6 1.1 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Suf PF05843.9 CDJ65718.1 - 0.33 10.6 5.9 0.33 10.6 4.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GSIII_N PF12437.3 CDJ65718.1 - 0.42 9.9 3.2 0.52 9.6 2.0 1.3 1 1 0 1 1 1 0 Glutamine synthetase type III N terminal Med15 PF09606.5 CDJ65718.1 - 0.45 8.6 19.8 0.5 8.5 13.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Jun PF03957.8 CDJ65718.1 - 0.51 10.0 11.4 0.6 9.7 7.9 1.0 1 0 0 1 1 1 0 Jun-like transcription factor DivIC PF04977.10 CDJ65718.1 - 1.5 8.3 7.5 2.3 7.7 5.2 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF788 PF05620.6 CDJ65718.1 - 2.5 7.9 5.4 3.2 7.5 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Zea_mays_MuDR PF05928.6 CDJ65718.1 - 3.2 7.1 5.6 3.1 7.1 3.9 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) TFIIA PF03153.8 CDJ65718.1 - 4.9 6.9 15.7 5.1 6.8 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RabGAP-TBC PF00566.13 CDJ65719.1 - 6.2e-22 78.1 0.1 7.8e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4349 PF14257.1 CDJ65719.1 - 0.1 11.7 1.7 0.73 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Cytochrom_B_N_2 PF13631.1 CDJ65720.1 - 0.0065 16.2 0.2 0.008 15.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB SR-25 PF10500.4 CDJ65721.1 - 0.0015 18.0 11.8 0.0015 18.0 8.2 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Ribosomal_S21 PF01165.15 CDJ65721.1 - 0.12 11.8 2.2 3.5 7.1 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S21 DDE_Tnp_1_6 PF13751.1 CDJ65721.1 - 0.23 11.4 11.1 0.024 14.6 4.7 1.6 2 0 0 2 2 2 0 Transposase DDE domain Apt1 PF10351.4 CDJ65721.1 - 0.28 10.0 2.1 0.37 9.5 0.0 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Chorion_2 PF03964.10 CDJ65721.1 - 0.33 11.5 20.8 0.8 10.2 0.2 3.3 3 0 0 3 3 3 0 Chorion family 2 BAF1_ABF1 PF04684.8 CDJ65721.1 - 0.39 9.5 8.5 0.89 8.3 5.9 1.6 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.14 CDJ65721.1 - 0.81 10.1 20.0 0.71 10.3 6.6 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3446 PF11928.3 CDJ65721.1 - 0.84 9.8 16.5 0.4 10.8 9.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF508 PF04370.7 CDJ65721.1 - 8.8 5.9 9.0 17 5.0 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Ribosomal_L1 PF00687.16 CDJ65722.1 - 2.4e-47 161.1 4.9 2.7e-47 160.9 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family U3snoRNP10 PF12397.3 CDJ65722.1 - 0.15 11.9 0.9 0.38 10.7 0.1 2.0 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Ribosomal_S24e PF01282.14 CDJ65723.1 - 2e-22 78.7 0.0 2.7e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e FIST PF08495.5 CDJ65724.1 - 1.8 7.6 8.8 0.72 8.9 4.0 1.7 1 1 1 2 2 2 0 FIST N domain IncA PF04156.9 CDJ65725.1 - 0.0057 16.2 0.4 0.0057 16.2 0.3 2.2 2 0 0 2 2 2 1 IncA protein Spt20 PF12090.3 CDJ65725.1 - 0.049 12.9 14.7 0.33 10.2 0.0 2.2 2 0 0 2 2 2 0 Spt20 family SAPS PF04499.10 CDJ65725.1 - 0.052 12.1 2.5 0.061 11.9 1.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SR-25 PF10500.4 CDJ65725.1 - 0.29 10.5 12.3 0.091 12.2 6.3 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ65725.1 - 0.61 9.0 19.4 0.56 9.2 9.3 2.0 2 0 0 2 2 2 0 Fms-interacting protein Suf PF05843.9 CDJ65725.1 - 0.65 9.6 16.3 1.9 8.1 8.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TMEM51 PF15345.1 CDJ65725.1 - 0.82 9.3 11.8 0.17 11.5 4.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 DUF566 PF04484.7 CDJ65725.1 - 0.85 9.0 14.8 0.99 8.8 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) TFIIA PF03153.8 CDJ65725.1 - 0.88 9.3 35.4 1.1 9.0 24.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.6 CDJ65725.1 - 0.95 9.5 24.9 0.21 11.6 11.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) BORG_CEP PF14957.1 CDJ65725.1 - 1 10.2 8.4 1.4 9.8 3.8 2.1 2 0 0 2 2 2 0 Cdc42 effector Sporozoite_P67 PF05642.6 CDJ65725.1 - 1.6 6.5 10.0 2 6.1 7.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SMC_hinge PF06470.8 CDJ65725.1 - 2.7 7.9 9.7 0.48 10.4 3.5 2.0 1 1 1 2 2 2 0 SMC proteins Flexible Hinge Domain DUF3121 PF11319.3 CDJ65725.1 - 2.9 7.3 13.5 0.11 11.9 4.8 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3121) Peptidase_S49_N PF08496.5 CDJ65725.1 - 3.6 7.3 10.7 17 5.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal vMSA PF00695.14 CDJ65725.1 - 3.8 6.6 6.3 5.7 6.0 4.4 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Plasmodium_Vir PF05795.6 CDJ65725.1 - 3.9 6.5 4.6 5.8 6.0 3.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FCP1_C PF09309.5 CDJ65725.1 - 4.3 6.5 18.6 4.7 6.4 9.9 2.1 2 0 0 2 2 2 0 FCP1, C-terminal MRI PF15325.1 CDJ65725.1 - 4.8 8.1 7.5 13 6.7 4.6 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection Apc15p PF05841.6 CDJ65725.1 - 5 7.8 16.9 13 6.4 9.6 2.1 2 0 0 2 2 2 0 Apc15p protein CRF1 PF10380.4 CDJ65725.1 - 5.1 7.4 8.4 8.2 6.7 3.5 2.1 2 0 0 2 2 2 0 Transcription factor CRF1 DUF3371 PF11851.3 CDJ65725.1 - 6.7 7.3 22.0 12 6.6 9.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) RPN7 PF10602.4 CDJ65727.1 - 4.7e-32 110.7 2.8 1.1e-29 103.0 0.1 2.1 1 1 1 2 2 2 2 26S proteasome subunit RPN7 Hanta_nucleocap PF00846.13 CDJ65727.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein RNA_pol_A_bac PF01000.21 CDJ65728.1 - 1.2e-10 41.4 0.0 2.9e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CDJ65728.1 - 4.2e-09 35.3 0.0 9.9e-09 34.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_S49_N PF08496.5 CDJ65728.1 - 0.28 10.9 5.3 0.098 12.4 1.5 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SpoIIIAH PF12685.2 CDJ65729.1 - 1.2 8.5 13.1 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Ras_bdg_2 PF14847.1 CDJ65731.1 - 1 9.3 0.0 1 9.3 0.0 3.2 3 1 1 4 4 4 0 Ras-binding domain of Byr2 ASCH PF04266.9 CDJ65732.1 - 3.2e-06 27.4 0.0 4.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ASCH domain Spt20 PF12090.3 CDJ65732.1 - 0.11 11.8 0.7 0.16 11.3 0.5 1.4 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.4 CDJ65732.1 - 3.9 6.8 21.0 3.2 7.1 10.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Aha1_N PF09229.6 CDJ65733.1 - 7.6e-13 48.4 0.0 2.2e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Chromo PF00385.19 CDJ65734.1 - 2.2e-13 49.6 0.0 4.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDJ65734.1 - 0.0045 17.0 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Pribosyltran PF00156.22 CDJ65736.1 - 4.9e-11 42.4 0.0 9e-11 41.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 CDJ65736.1 - 0.056 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase CTP_transf_2 PF01467.21 CDJ65737.1 - 1.6e-18 67.2 0.1 2.9e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Cytidylyltransferase Myosin_head PF00063.16 CDJ65738.1 - 1.3e-37 129.2 0.0 5.9e-20 70.8 0.0 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) IQ PF00612.22 CDJ65738.1 - 4.2e-17 60.0 33.4 4.5e-05 22.7 0.1 7.3 7 0 0 7 7 7 5 IQ calmodulin-binding motif SprA-related PF12118.3 CDJ65740.1 - 1.2e-06 28.0 23.3 1.5e-06 27.7 16.1 1.2 1 0 0 1 1 1 1 SprA-related family Dehydrin PF00257.14 CDJ65740.1 - 0.0034 17.7 6.8 0.0034 17.7 4.7 2.3 2 0 0 2 2 1 1 Dehydrin FimP PF09766.4 CDJ65740.1 - 0.0073 15.4 17.7 0.0083 15.2 12.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein IncA PF04156.9 CDJ65740.1 - 0.034 13.7 20.7 0.044 13.3 14.4 1.2 1 0 0 1 1 1 0 IncA protein LIM_bind PF01803.11 CDJ65740.1 - 0.49 9.4 14.9 0.62 9.1 10.3 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Med15 PF09606.5 CDJ65740.1 - 1 7.4 39.4 1.2 7.2 27.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ65740.1 - 2.1 8.1 33.3 2.5 7.8 23.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.3 CDJ65740.1 - 2.8 6.5 40.5 4.1 6.0 28.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HCO3_cotransp PF00955.16 CDJ65740.1 - 4.1 5.9 5.1 5.2 5.6 3.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family RR_TM4-6 PF06459.7 CDJ65740.1 - 5.2 6.8 13.8 6.9 6.4 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 CDJ65740.1 - 7.6 6.7 15.5 10 6.3 10.8 1.1 1 0 0 1 1 1 0 AAA domain Nucleoside_tran PF01733.13 CDJ65741.1 - 1e-08 34.7 1.5 2.6e-05 23.5 1.1 2.6 2 0 0 2 2 2 2 Nucleoside transporter DUF788 PF05620.6 CDJ65741.1 - 0.0052 16.6 0.4 0.0052 16.6 0.3 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF788) DUF3357 PF11837.3 CDJ65741.1 - 9.8 6.0 10.3 15 5.5 0.3 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) Lbh PF15317.1 CDJ65743.1 - 0.11 12.7 1.7 5.2 7.3 0.2 2.4 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein LRR19-TM PF15176.1 CDJ65744.1 - 0.051 13.2 0.3 0.89 9.2 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain LRR19-TM PF15176.1 CDJ65745.1 - 0.05 13.2 0.3 0.88 9.2 0.0 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF3408 PF11888.3 CDJ65746.1 - 2e-12 47.1 0.2 0.005 16.7 0.0 6.0 6 1 1 7 7 7 3 Protein of unknown function (DUF3408) RHH_1 PF01402.16 CDJ65746.1 - 0.093 12.6 7.9 18 5.4 0.0 5.3 6 0 0 6 6 6 0 Ribbon-helix-helix protein, copG family DUF2163 PF09931.4 CDJ65746.1 - 0.19 11.4 1.8 1.5e+02 2.1 0.0 4.4 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2163) SurA_N_2 PF13623.1 CDJ65746.1 - 0.71 9.8 11.4 34 4.3 0.1 5.6 5 1 0 6 6 6 0 SurA N-terminal domain Lbh PF15317.1 CDJ65746.1 - 1.2 9.4 18.3 20 5.5 0.0 6.2 7 0 0 7 7 7 0 Cardiac transcription factor regulator, Developmental protein Chlorophyllase PF07224.6 CDJ65746.1 - 3.6 6.3 14.2 0.42 9.3 0.0 5.4 8 0 0 8 8 8 0 Chlorophyllase PAM2 PF07145.10 CDJ65747.1 - 0.0013 18.0 1.2 0.0029 17.0 0.8 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Nucleoside_tran PF01733.13 CDJ65749.1 - 6e-12 45.3 2.8 6e-12 45.3 1.9 1.8 2 0 0 2 2 2 1 Nucleoside transporter K_channel_TID PF07941.6 CDJ65750.1 - 1.4 9.1 9.3 0.61 10.3 2.3 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TFIIA PF03153.8 CDJ65750.1 - 2.2 8.1 14.6 2.8 7.7 10.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.7 CDJ65750.1 - 5.8 5.7 5.6 6.2 5.6 3.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor VID27 PF08553.5 CDJ65751.1 - 2e-31 109.0 4.7 8.9e-31 106.9 0.0 2.8 3 0 0 3 3 3 1 VID27 cytoplasmic protein Suf PF05843.9 CDJ65751.1 - 0.0052 16.5 3.3 0.0052 16.5 2.3 1.6 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ65751.1 - 0.017 13.3 23.7 0.031 12.5 16.5 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDJ65751.1 - 0.029 13.8 49.4 0.051 13.0 8.2 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ65751.1 - 0.048 12.7 8.2 0.077 12.0 5.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDJ65751.1 - 0.078 12.3 3.8 0.16 11.3 2.6 1.5 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.4 CDJ65751.1 - 0.28 9.3 18.5 0.41 8.8 12.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDJ65751.1 - 1.4 8.9 23.6 0.12 12.4 7.6 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_C13 PF01650.13 CDJ65752.1 - 9.1e-27 93.9 0.0 3.7e-20 72.3 0.0 4.0 3 1 1 4 4 4 2 Peptidase C13 family SpoIIIAH PF12685.2 CDJ65752.1 - 0.0056 16.1 27.6 0.052 13.0 6.9 3.1 3 0 0 3 3 3 2 SpoIIIAH-like protein Spore_coat_CotO PF14153.1 CDJ65752.1 - 0.0061 16.0 14.1 0.0061 16.0 9.8 3.8 3 1 0 3 3 3 1 Spore coat protein CotO FimP PF09766.4 CDJ65752.1 - 0.0075 15.3 20.1 0.0075 15.3 13.9 4.5 3 1 0 4 4 4 1 Fms-interacting protein DDHD PF02862.12 CDJ65752.1 - 0.0089 15.8 9.1 0.0089 15.8 6.3 3.3 3 0 0 3 3 3 1 DDHD domain Peptidase_C25 PF01364.13 CDJ65752.1 - 0.038 12.9 5.8 0.16 10.9 0.8 2.6 2 0 0 2 2 2 0 Peptidase family C25 SAPS PF04499.10 CDJ65752.1 - 0.075 11.6 18.2 0.0031 16.2 2.6 2.4 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.11 CDJ65752.1 - 0.092 11.7 6.3 1.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF605 PF04652.11 CDJ65752.1 - 0.27 10.6 57.9 0.038 13.3 9.1 3.2 3 0 0 3 3 3 0 Vta1 like Plasmodium_Vir PF05795.6 CDJ65752.1 - 3.9 6.5 10.0 2.5 7.2 2.3 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF2722 PF10846.3 CDJ65753.1 - 0.031 13.3 0.2 0.031 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF1360 PF07098.6 CDJ65753.1 - 0.042 13.5 3.0 0.038 13.7 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1360) Med15 PF09606.5 CDJ65753.1 - 0.072 11.2 15.7 0.096 10.8 10.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDJ65753.1 - 1.2 7.8 15.0 1.3 7.6 10.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.8 CDJ65753.1 - 8.9 6.3 14.5 34 4.4 10.1 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_2 PF13639.1 CDJ65754.1 - 3.8e-11 42.6 14.1 3.8e-11 42.6 9.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CDJ65754.1 - 2e-06 27.7 6.9 2e-06 27.7 4.8 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDJ65754.1 - 0.00011 22.2 13.9 0.00011 22.2 9.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDJ65754.1 - 0.00014 21.4 14.0 0.00014 21.4 9.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ65754.1 - 0.00026 20.6 13.9 0.00026 20.6 9.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Eapp_C PF10238.4 CDJ65754.1 - 0.0097 15.8 0.9 0.0097 15.8 0.6 4.4 5 1 1 6 6 6 1 E2F-associated phosphoprotein SUKH_6 PF14568.1 CDJ65754.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall zf-RING_UBOX PF13445.1 CDJ65754.1 - 0.48 10.1 8.8 3.2 7.5 6.2 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 CDJ65754.1 - 0.7 9.7 9.0 0.21 11.4 3.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CDJ65754.1 - 0.73 9.5 15.6 0.038 13.6 6.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAM222A PF15258.1 CDJ65755.1 - 0.00015 21.1 0.6 0.00015 21.1 0.4 4.8 2 1 2 4 4 4 1 Protein family of FAM222A TIM PF00121.13 CDJ65756.1 - 2.2e-47 161.1 0.0 4.2e-23 81.6 0.2 2.2 1 1 1 2 2 2 2 Triosephosphate isomerase RskA PF10099.4 CDJ65756.1 - 0.17 11.6 9.2 3.2 7.4 6.4 2.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA MT-A70 PF05063.9 CDJ65757.1 - 2.1e-56 190.2 0.4 2.1e-56 190.2 0.3 2.8 3 0 0 3 3 3 1 MT-A70 CAF-1_p150 PF11600.3 CDJ65757.1 - 0.0019 17.5 16.2 0.0019 17.5 11.2 3.2 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 CDJ65757.1 - 8.2 4.8 7.6 11 4.4 0.2 2.5 2 0 0 2 2 2 0 LMBR1-like membrane protein LRR_4 PF12799.2 CDJ65758.1 - 8.9e-18 63.5 6.8 1.1e-06 28.1 0.5 4.8 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ65758.1 - 1e-08 34.7 11.0 0.0011 18.6 0.1 3.9 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CDJ65758.1 - 2.2e-05 23.8 9.0 6.7 7.1 0.5 6.3 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 CDJ65758.1 - 0.055 13.6 17.9 3.9 8.0 0.0 7.0 8 0 0 8 8 8 0 Leucine rich repeat LRR_6 PF13516.1 CDJ65758.1 - 0.097 12.7 5.1 36 4.8 0.0 5.4 4 2 2 6 6 6 0 Leucine Rich repeat Ank_2 PF12796.2 CDJ65759.1 - 2.8e-18 66.0 0.7 9.7e-11 41.8 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ65759.1 - 8.2e-16 56.9 3.6 2.8e-10 39.4 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CDJ65759.1 - 1.2e-15 57.4 0.6 1e-08 35.4 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CDJ65759.1 - 4.1e-15 55.6 2.2 4.1e-15 55.6 1.5 2.4 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_5 PF13857.1 CDJ65759.1 - 8.2e-12 44.9 4.2 4.6e-10 39.4 0.1 3.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ65759.1 - 3.5e-09 36.0 1.6 3.6e-06 26.6 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat QCR10 PF09796.4 CDJ65759.1 - 0.051 13.2 0.7 0.3 10.7 0.0 2.7 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF3446 PF11928.3 CDJ65759.1 - 0.83 9.8 18.5 1.2 9.4 4.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) MpPF26 PF07666.6 CDJ65759.1 - 2.4 8.0 9.7 0.11 12.3 2.4 1.9 2 0 0 2 2 2 0 M penetrans paralogue family 26 Ribosomal_L19 PF01245.15 CDJ65760.1 - 3.1e-14 52.7 0.0 5.3e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Alpha-amylase PF00128.19 CDJ65763.1 - 4.4e-21 75.6 0.0 1.4e-13 50.9 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amyl_C2 PF07821.7 CDJ65763.1 - 2.5e-11 43.2 0.2 6.9e-11 41.8 0.1 1.8 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain fn3 PF00041.16 CDJ65763.1 - 1.8e-08 34.3 0.0 1.1e-06 28.7 0.0 3.1 2 0 0 2 2 2 1 Fibronectin type III domain Calpain_III PF01067.17 CDJ65764.1 - 0.051 13.2 0.2 9.7 5.8 0.0 3.5 4 2 0 4 4 4 0 Calpain large subunit, domain III RES PF08808.6 CDJ65765.1 - 0.0095 16.0 5.3 0.15 12.1 0.8 2.4 1 1 1 2 2 2 2 RES domain Peptidase_C2 PF00648.16 CDJ65765.1 - 0.048 12.6 0.0 2.7 6.9 0.0 2.3 1 1 0 2 2 2 0 Calpain family cysteine protease PhyH PF05721.8 CDJ65767.1 - 0.00021 21.4 0.3 0.066 13.2 0.0 2.7 2 1 1 3 3 3 2 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 CDJ65767.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Cullin PF00888.17 CDJ65768.1 - 2.5e-116 389.5 6.4 3.7e-116 389.0 4.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CDJ65768.1 - 4.6e-24 84.0 0.2 1.9e-23 82.0 0.2 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3658 PF12395.3 CDJ65768.1 - 0.002 17.6 0.1 0.033 13.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function DUF4449 PF14613.1 CDJ65768.1 - 0.078 12.8 5.9 8 6.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4449) DUF445 PF04286.7 CDJ65768.1 - 0.093 12.2 8.5 0.081 12.4 1.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF445) PKD_channel PF08016.7 CDJ65769.1 - 3.5e-08 32.2 14.5 3.5e-08 32.2 10.0 1.9 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 CDJ65769.1 - 0.033 13.4 17.6 0.074 12.2 12.2 1.5 1 0 0 1 1 1 0 Ion transport protein PilM PF07419.7 CDJ65769.1 - 0.081 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 PilM PKD_channel PF08016.7 CDJ65770.1 - 0.0025 16.2 9.8 0.0025 16.2 6.8 2.9 4 0 0 4 4 4 2 Polycystin cation channel EXS PF03124.9 CDJ65770.1 - 0.6 9.0 7.8 0.18 10.8 2.6 2.2 2 1 0 2 2 2 0 EXS family PKD_channel PF08016.7 CDJ65772.1 - 3.4e-09 35.6 12.7 3.4e-09 35.6 8.8 3.1 4 0 0 4 4 4 1 Polycystin cation channel Ion_trans PF00520.26 CDJ65772.1 - 0.0017 17.6 16.4 0.0017 17.6 11.4 2.5 2 0 0 2 2 2 1 Ion transport protein Kinesin PF00225.18 CDJ65773.1 - 7.4e-86 287.8 0.0 1.3e-43 149.0 0.0 2.5 1 1 1 2 2 2 2 Kinesin motor domain KIF1B PF12423.3 CDJ65773.1 - 0.023 14.7 0.0 0.088 12.8 0.0 2.1 1 0 0 1 1 1 0 Kinesin protein 1B FHA PF00498.21 CDJ65773.1 - 0.075 13.1 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 FHA domain Retrotrans_gag PF03732.12 CDJ65774.1 - 0.0047 16.9 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein rve PF00665.21 CDJ65775.1 - 4e-06 26.9 0.0 1.7e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CDJ65775.1 - 0.002 17.5 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.3 CDJ65775.1 - 0.013 14.6 0.2 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-H2C2 PF09337.5 CDJ65775.1 - 0.044 13.1 1.1 0.088 12.2 0.8 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger zf-RVT PF13966.1 CDJ65776.1 - 1.3e-06 28.6 0.5 4.4e-06 26.9 0.4 1.9 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase GSH-S_ATP PF02955.11 CDJ65776.1 - 0.033 13.3 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain P16-Arc PF04699.9 CDJ65776.1 - 0.047 13.7 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) TFIID-18kDa PF02269.11 CDJ65776.1 - 0.092 12.5 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Antiterm PF03589.8 CDJ65776.1 - 0.1 12.6 0.2 22 5.2 0.0 2.7 1 1 1 2 2 2 0 Antitermination protein DUF45 PF01863.12 CDJ65777.1 - 0.0037 17.0 0.0 0.0037 17.0 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function DUF45 DNA_pol_B_exo1 PF03104.14 CDJ65778.1 - 0.00083 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CDJ65779.1 - 4.9e-30 104.7 0.1 2.4e-29 102.4 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B PF00136.16 CDJ65780.1 - 1.1e-33 116.7 0.0 1.6e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 CDJ65780.1 - 1.4e-11 44.1 4.4 1.4e-11 44.1 3.0 2.5 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta PAM2 PF07145.10 CDJ65781.1 - 9.9e-05 21.5 0.6 0.00026 20.2 0.4 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Mito_fiss_reg PF05308.6 CDJ65781.1 - 1.2 8.5 11.1 0.06 12.7 3.4 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Histone PF00125.19 CDJ65783.1 - 5.8e-34 116.0 0.3 7.3e-34 115.7 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDJ65783.1 - 0.00015 21.8 0.0 0.0002 21.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CDJ65783.1 - 0.0039 17.2 0.0 0.0053 16.7 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 CDJ65783.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.17 CDJ65784.1 - 4.8e-13 48.5 0.1 3.5e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ65784.1 - 2.9e-12 46.3 0.0 1.1e-10 41.2 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ65784.1 - 0.00072 19.3 0.1 0.0026 17.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.22 CDJ65785.1 - 3.2e-05 23.5 0.0 0.00023 20.7 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase OmpH PF03938.9 CDJ65785.1 - 0.013 15.4 0.8 0.013 15.4 0.5 6.3 5 2 0 5 5 5 0 Outer membrane protein (OmpH-like) MFS_1 PF07690.11 CDJ65786.1 - 2.3e-06 26.6 9.4 2.3e-06 26.6 6.5 3.5 3 2 0 3 3 3 2 Major Facilitator Superfamily UPF0542 PF15086.1 CDJ65786.1 - 0.38 10.4 1.9 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Macoilin PF09726.4 CDJ65786.1 - 1.7 6.8 5.6 4.1 5.5 3.9 1.7 1 1 0 1 1 1 0 Transmembrane protein MFS_2 PF13347.1 CDJ65786.1 - 2.6 6.3 17.5 0.025 13.0 0.7 3.4 2 2 1 3 3 3 0 MFS/sugar transport protein Peptidase_C65 PF10275.4 CDJ65787.1 - 3e-51 174.1 0.0 3e-51 174.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase C65 Otubain OTU PF02338.14 CDJ65787.1 - 0.0036 17.8 0.8 0.1 13.2 0.0 3.0 2 1 0 2 2 2 1 OTU-like cysteine protease PAT1 PF09770.4 CDJ65787.1 - 0.1 10.7 25.3 0.13 10.4 17.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDJ65787.1 - 0.95 8.7 22.1 1.4 8.1 15.3 1.2 1 0 0 1 1 1 0 SprA-related family HlyD_2 PF12700.2 CDJ65787.1 - 2.3 7.2 7.1 2.9 6.9 4.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein U1snRNP70_N PF12220.3 CDJ65787.1 - 6.7 7.1 15.6 3.9 7.8 4.4 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FCP1_C PF09309.5 CDJ65787.1 - 9.1 5.4 13.1 1.2 8.3 0.5 2.2 2 0 0 2 2 2 0 FCP1, C-terminal AnfO_nitrog PF09582.5 CDJ65789.1 - 0.015 14.4 1.9 0.12 11.5 0.0 2.4 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Pex14_N PF04695.8 CDJ65789.1 - 2.4 8.2 16.1 0.026 14.5 1.2 3.6 3 2 2 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AP2 PF00847.15 CDJ65790.1 - 3.9e-06 26.9 0.1 3.9e-06 26.9 0.0 4.3 5 1 0 5 5 5 1 AP2 domain BAF1_ABF1 PF04684.8 CDJ65790.1 - 0.0014 17.5 13.4 0.0014 17.5 9.3 8.4 8 1 0 8 8 8 2 BAF1 / ABF1 chromatin reorganising factor BAF1_ABF1 PF04684.8 CDJ65793.1 - 0.0023 16.8 11.6 0.0023 16.8 8.1 2.8 2 1 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CDJ65793.1 - 0.18 11.1 6.4 0.3 10.4 4.5 1.2 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.4 CDJ65794.1 - 0.0014 18.1 4.6 0.0014 18.1 3.2 5.3 4 1 1 5 5 5 4 Nuclear RNA-splicing-associated protein FlaG PF03646.10 CDJ65794.1 - 1.2 9.3 6.7 1.3 9.2 1.9 3.1 3 0 0 3 3 3 0 FlaG protein SR-25 PF10500.4 CDJ65796.1 - 0.21 11.0 11.5 0.096 12.1 5.7 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sad1_UNC PF07738.8 CDJ65797.1 - 3.8e-17 62.3 0.0 1.4e-11 44.3 0.0 3.4 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal DUF1091 PF06477.8 CDJ65797.1 - 0.054 13.9 0.0 0.095 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) ExbD PF02472.11 CDJ65797.1 - 2.8 7.9 7.0 6.2 6.8 4.2 2.1 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF342 PF03961.8 CDJ65797.1 - 3.1 6.1 7.2 5.6 5.2 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SoxE PF06525.6 CDJ65797.1 - 8 5.6 8.1 6.6 5.9 0.2 2.4 2 0 0 2 2 2 0 Sulfocyanin (SoxE) Lin-8 PF03353.10 CDJ65798.1 - 2.5 7.2 8.8 4 6.6 6.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SOG2 PF10428.4 CDJ65798.1 - 2.8 6.5 22.9 3.9 6.0 15.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF605 PF04652.11 CDJ65798.1 - 6.3 6.0 23.7 8.5 5.6 16.4 1.1 1 0 0 1 1 1 0 Vta1 like SR-25 PF10500.4 CDJ65799.1 - 3.4e-06 26.6 9.3 3.4e-06 26.6 6.5 3.0 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein Tmemb_9 PF05434.6 CDJ65799.1 - 0.022 14.4 0.0 0.022 14.4 0.0 4.1 3 2 2 5 5 5 0 TMEM9 Med15 PF09606.5 CDJ65799.1 - 0.032 12.4 0.0 0.032 12.4 0.0 2.8 1 1 2 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glyco_hydro_3_C PF01915.17 CDJ65800.1 - 4.1 6.8 15.3 4.7 6.6 9.3 2.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Peptidase_U57 PF05582.7 CDJ65800.1 - 6.2 5.6 17.6 0.13 11.1 0.1 2.4 2 0 0 2 2 2 0 YabG peptidase U57 SR-25 PF10500.4 CDJ65801.1 - 0.00057 19.4 8.9 0.00057 19.4 6.2 6.7 7 1 0 7 7 7 1 Nuclear RNA-splicing-associated protein DUF342 PF03961.8 CDJ65802.1 - 2.6 6.3 14.5 3.6 5.9 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SPT16 PF08644.6 CDJ65802.1 - 3.3 7.5 14.0 0.5 10.1 7.2 1.5 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DIT1_PvcA PF05141.7 CDJ65802.1 - 5.9 6.1 12.1 9.9 5.3 8.4 1.5 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein BAF1_ABF1 PF04684.8 CDJ65803.1 - 0.03 13.1 14.4 0.035 12.9 10.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Smoothelin PF12510.3 CDJ65803.1 - 0.15 11.9 0.8 15 5.5 0.0 2.8 3 0 0 3 3 3 0 Smoothelin cytoskeleton protein MSP1_C PF07462.6 CDJ65803.1 - 0.27 9.5 6.0 0.31 9.3 4.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Gly-zipper_OmpA PF13436.1 CDJ65803.1 - 0.42 10.2 15.6 0.82 9.3 10.8 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF3138 PF11336.3 CDJ65803.1 - 0.73 7.9 18.4 0.95 7.5 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4404 PF14357.1 CDJ65803.1 - 6.8 7.1 8.7 7.2 7.1 4.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1840 PF08895.6 CDJ65803.1 - 9.5 6.3 9.0 0.64 10.0 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Med15 PF09606.5 CDJ65803.1 - 9.9 4.2 15.3 10 4.1 10.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Rcd1 PF04078.8 CDJ65804.1 - 6.7e-22 77.5 0.0 7.9e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OS-D PF03392.8 CDJ65804.1 - 0.012 15.5 0.6 0.018 14.9 0.4 1.3 1 1 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Retrotrans_gag PF03732.12 CDJ65805.1 - 0.036 14.1 0.0 0.088 12.8 0.0 1.6 2 0 0 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.1 CDJ65806.1 - 1.3e-05 25.6 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDJ65806.1 - 0.00023 20.9 0.0 0.0005 19.9 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CDJ65806.1 - 0.00043 20.0 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ65806.1 - 0.00043 20.2 0.0 0.00077 19.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ65806.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DUF1528 PF07515.6 CDJ65807.1 - 0.067 13.2 0.5 0.085 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1528) Activator_LAG-3 PF11498.3 CDJ65807.1 - 0.084 11.6 11.1 0.095 11.4 7.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TH1 PF04858.8 CDJ65808.1 - 0.0064 14.7 0.0 0.013 13.7 0.0 1.7 1 1 0 1 1 1 1 TH1 protein PAT1 PF09770.4 CDJ65808.1 - 1.9 6.6 11.6 2.3 6.3 8.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDJ65809.1 - 5.3e-06 26.0 9.0 5.3e-06 26.0 6.3 3.3 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein TAF1D PF15333.1 CDJ65809.1 - 7.8 6.2 16.3 5.5 6.7 4.1 2.4 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Macoilin PF09726.4 CDJ65811.1 - 0.41 8.8 3.9 0.57 8.3 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 CDJ65811.1 - 0.5 9.7 16.7 0.92 8.9 11.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ65811.1 - 4.2 6.6 6.1 5.9 6.2 4.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 CDJ65811.1 - 7.6 4.4 10.4 9.7 4.1 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ETRAMP PF09716.5 CDJ65812.1 - 0.018 14.9 4.4 0.022 14.6 3.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Hc1 PF07432.8 CDJ65812.1 - 1.5 8.9 19.8 1.7 8.8 13.7 1.0 1 0 0 1 1 1 0 Histone H1-like protein Hc1 GOLD_2 PF13897.1 CDJ65812.1 - 4.8 7.4 5.5 4.8 7.4 3.8 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking TEX19 PF15553.1 CDJ65812.1 - 6.7 6.5 8.1 7.6 6.3 5.6 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 Pex14_N PF04695.8 CDJ65812.1 - 7.6 6.5 15.8 5.5 7.0 10.0 1.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAP PF00956.13 CDJ65814.1 - 5.3e-21 74.8 0.0 6.5e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) PROCN PF08083.6 CDJ65815.1 - 9.4e-218 722.5 4.3 1.4e-217 722.0 3.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CDJ65815.1 - 3.4e-123 409.3 0.3 5.5e-123 408.7 0.2 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CDJ65815.1 - 4.6e-92 305.6 1.3 9.4e-92 304.6 0.9 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CDJ65815.1 - 3.3e-78 260.5 0.1 7.3e-78 259.4 0.1 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CDJ65815.1 - 7.9e-68 226.2 0.1 1.4e-67 225.4 0.0 1.4 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CDJ65815.1 - 5.9e-43 144.6 0.0 1.3e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Mitofilin PF09731.4 CDJ65815.1 - 1.6 7.2 10.8 2.7 6.5 7.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1042 PF06294.6 CDJ65817.1 - 0.73 9.4 14.4 3.1 7.3 0.9 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1042) Spt20 PF12090.3 CDJ65818.1 - 4 6.7 9.0 9.6 5.5 0.1 2.3 2 0 0 2 2 2 0 Spt20 family MPC PF03650.8 CDJ65819.1 - 8.8e-13 48.2 0.4 2.8e-11 43.4 0.2 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0041) DUF515 PF04415.7 CDJ65819.1 - 6.5 4.8 9.2 7.4 4.6 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) LSM PF01423.17 CDJ65820.1 - 2.2e-18 65.5 0.0 2.7e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Tox-REase-3 PF15647.1 CDJ65820.1 - 0.099 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 Pkinase PF00069.20 CDJ65821.1 - 8.9e-50 169.2 0.0 2.7e-48 164.4 0.0 3.4 2 1 0 2 2 2 1 Protein kinase domain Glycolytic PF00274.14 CDJ65822.1 - 9.3e-168 557.0 0.0 1e-167 556.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Rad10 PF03834.9 CDJ65823.1 - 4.5e-19 67.9 0.0 1.2e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.18 CDJ65823.1 - 0.0024 17.5 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SAPS PF04499.10 CDJ65823.1 - 0.0034 16.0 16.5 0.0048 15.6 11.5 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein LMBR1 PF04791.11 CDJ65823.1 - 0.0044 15.6 6.1 0.0046 15.5 4.2 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Mem_trans PF03547.13 CDJ65823.1 - 0.005 15.1 2.6 0.0061 14.8 1.8 1.2 1 0 0 1 1 1 1 Membrane transport protein Exonuc_VII_L PF02601.10 CDJ65823.1 - 0.019 14.1 24.0 0.037 13.2 15.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit HHH_2 PF12826.2 CDJ65823.1 - 0.035 14.0 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.1 CDJ65823.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ndc1_Nup PF09531.5 CDJ65823.1 - 0.14 10.5 22.2 0.18 10.1 15.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4638 PF15472.1 CDJ65823.1 - 1.4 8.4 30.9 2.5 7.6 21.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SAGA-Tad1 PF12767.2 CDJ65823.1 - 1.8 8.1 35.5 3.1 7.3 24.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ALMT PF11744.3 CDJ65823.1 - 2.7 6.5 5.6 3.1 6.3 3.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Thioredoxin_6 PF13848.1 CDJ65824.1 - 0.003 17.3 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 CDJ65824.1 - 0.012 15.2 0.4 0.058 13.0 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin MDMPI_N PF11716.3 CDJ65824.1 - 0.8 10.1 0.0 0.8 10.1 0.0 2.3 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain K_channel_TID PF07941.6 CDJ65825.1 - 0.11 12.7 1.7 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain AMP-binding PF00501.23 CDJ65826.1 - 5.7e-33 113.9 0.0 1.3e-32 112.7 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 CDJ65827.1 - 1.6e-85 286.6 0.7 2.6e-85 285.9 0.5 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CDJ65827.1 - 8.3e-42 141.7 0.0 2.2e-41 140.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 CDJ65827.1 - 1.3e-35 122.9 1.0 6e-22 78.1 0.0 2.8 3 0 0 3 3 3 2 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 CDJ65827.1 - 1.7e-29 103.2 0.1 3.1e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain AMP-binding PF00501.23 CDJ65827.1 - 1.9e-26 92.4 0.0 1.2e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 CDJ65827.1 - 1.8e-10 40.8 0.2 4.7e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 CDJ65827.1 - 5e-05 22.4 0.3 5e-05 22.4 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain AMP-binding_C_2 PF14535.1 CDJ65827.1 - 0.00073 19.5 0.0 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACP_syn_III PF08545.5 CDJ65827.1 - 0.023 14.3 0.7 0.074 12.7 0.5 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ribosomal_L22 PF00237.14 CDJ65828.1 - 2.4e-15 56.3 0.2 3.2e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Longin PF13774.1 CDJ65829.1 - 2.1e-10 40.0 0.0 3.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CDJ65829.1 - 0.0045 16.5 0.9 0.0075 15.8 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF3726 PF12525.3 CDJ65830.1 - 0.13 12.0 0.9 0.15 11.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) DUF1014 PF06244.7 CDJ65832.1 - 3.1e-30 104.8 19.2 5.1e-28 97.7 13.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 CDJ65832.1 - 6.2e-05 23.1 0.3 6.2e-05 23.1 0.2 2.6 2 1 0 2 2 2 1 HMG (high mobility group) box CHDNT PF08073.7 CDJ65832.1 - 0.044 13.4 0.1 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.8 CDJ65832.1 - 0.066 13.4 0.3 0.066 13.4 0.2 2.2 1 1 1 2 2 2 0 YABBY protein TMPIT PF07851.8 CDJ65832.1 - 0.24 10.4 5.6 0.32 10.0 3.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein U79_P34 PF03064.11 CDJ65832.1 - 1.2 8.5 10.7 1.8 7.9 7.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Nefa_Nip30_N PF10187.4 CDJ65832.1 - 3.6 7.8 19.3 0.33 11.1 10.0 1.7 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2951 PF11166.3 CDJ65832.1 - 4.1 7.3 8.4 5.6 6.8 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) Vfa1 PF08432.5 CDJ65832.1 - 7.3 6.5 13.7 11 5.9 9.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WEMBL PF05701.6 CDJ65833.1 - 0.00011 20.7 16.2 0.00011 20.7 11.2 2.4 1 1 1 2 2 2 1 Weak chloroplast movement under blue light Phage_GP20 PF06810.6 CDJ65833.1 - 0.07 12.5 5.9 0.16 11.4 3.6 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 PRO8NT PF08082.6 CDJ65833.1 - 0.15 11.6 0.2 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain Atg14 PF10186.4 CDJ65833.1 - 0.21 10.4 16.2 0.29 10.0 10.3 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 CDJ65833.1 - 0.39 10.5 36.4 0.057 13.2 5.7 3.6 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CDJ65833.1 - 0.91 8.6 7.6 0.081 12.0 1.3 2.1 2 1 0 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 CDJ65833.1 - 0.96 9.3 4.1 4.3 7.3 1.3 2.9 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CDJ65833.1 - 3.1 7.6 8.0 0.17 11.6 0.6 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 CDJ65833.1 - 3.6 6.1 22.6 0.11 11.1 8.6 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein HALZ PF02183.13 CDJ65833.1 - 4.5 7.0 8.1 0.25 11.1 1.3 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 CDJ65833.1 - 8.9 6.4 14.0 6.6 6.8 5.4 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 CDJ65834.1 - 2.3e-17 62.1 1.6 1e-06 28.3 0.0 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat tRNA-synt_1c PF00749.16 CDJ65835.1 - 4.4e-67 225.9 0.0 1.4e-55 188.1 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain WD40 PF00400.27 CDJ65835.1 - 5.7e-46 152.8 19.2 1.2e-10 40.8 0.6 9.0 8 0 0 8 8 8 7 WD domain, G-beta repeat DUF3659 PF12396.3 CDJ65835.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Abhydrolase_5 PF12695.2 CDJ65836.1 - 4e-22 78.5 0.0 7.9e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ65836.1 - 4.2e-12 46.4 0.0 4.7e-10 39.7 0.0 3.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDJ65836.1 - 2e-09 36.9 0.3 1.3e-06 27.7 0.0 3.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 CDJ65836.1 - 0.0022 17.4 0.1 0.059 12.8 0.0 2.2 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CDJ65836.1 - 0.0025 17.3 0.0 0.024 14.0 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 CDJ65836.1 - 0.0029 17.2 0.1 0.037 13.5 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.7 CDJ65836.1 - 0.011 14.4 0.1 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 CDJ65836.1 - 0.019 14.8 0.1 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Pkinase PF00069.20 CDJ65837.1 - 3.7e-22 78.7 6.7 1.8e-10 40.4 0.0 4.0 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65837.1 - 2.4e-09 36.6 2.0 0.00013 21.1 0.0 4.8 5 0 0 5 5 5 3 Protein tyrosine kinase zf-DHHC PF01529.15 CDJ65838.1 - 3.5e-40 137.2 4.8 3.5e-40 137.2 3.3 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase RseC_MucC PF04246.7 CDJ65838.1 - 0.0029 17.1 3.8 0.016 14.8 0.4 2.5 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC Yip1 PF04893.12 CDJ65838.1 - 0.068 12.6 9.1 0.23 10.9 0.1 2.2 2 0 0 2 2 2 0 Yip1 domain CopD PF05425.8 CDJ65838.1 - 0.65 10.2 7.2 2.4 8.4 1.3 2.3 2 0 0 2 2 2 0 Copper resistance protein D OAD_gamma PF04277.8 CDJ65838.1 - 0.9 9.9 0.0 0.9 9.9 0.0 2.2 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Colicin_V PF02674.11 CDJ65838.1 - 2.9 7.7 16.5 0.058 13.2 3.4 2.3 2 1 0 2 2 2 0 Colicin V production protein START PF01852.14 CDJ65839.1 - 1.1e-10 41.2 0.0 6.1e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 START domain TP_methylase PF00590.15 CDJ65841.1 - 2.9e-19 69.6 0.0 5.6e-19 68.6 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Med15_fungi PF05397.7 CDJ65841.1 - 0.06 13.3 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 15 UQ_con PF00179.21 CDJ65842.1 - 4.8e-47 158.9 0.0 5.5e-47 158.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDJ65842.1 - 3.7e-05 23.4 0.0 4.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CDJ65842.1 - 0.00074 19.4 0.0 0.0009 19.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Rhomboid PF01694.17 CDJ65844.1 - 1.1e-16 61.1 15.6 2.1e-14 53.7 3.0 2.6 2 1 1 3 3 3 2 Rhomboid family MFS_1 PF07690.11 CDJ65844.1 - 0.094 11.4 5.7 0.14 10.8 4.0 1.3 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF1751 PF08551.5 CDJ65844.1 - 3.7 7.9 6.3 1.5 9.2 0.8 2.3 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) CoaE PF01121.15 CDJ65845.1 - 1.4e-47 161.4 0.0 1.7e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.1 CDJ65845.1 - 3.6e-06 27.0 0.0 6.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDJ65845.1 - 1.2e-05 26.1 0.1 2.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDJ65845.1 - 0.00054 20.2 0.1 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDJ65845.1 - 0.0069 16.2 0.0 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDJ65845.1 - 0.12 12.0 0.1 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain APG5 PF04106.7 CDJ65846.1 - 4.8e-26 91.4 0.0 3.9e-25 88.4 0.0 2.0 1 1 0 1 1 1 1 Autophagy protein Apg5 Ribosomal_60s PF00428.14 CDJ65846.1 - 0.00029 21.1 3.5 0.00029 21.1 2.4 3.5 4 0 0 4 4 4 1 60s Acidic ribosomal protein Chon_Sulph_att PF06566.6 CDJ65847.1 - 0.18 11.3 2.4 1.1 8.7 1.7 2.0 1 1 0 1 1 1 0 Chondroitin sulphate attachment domain MMgT PF10270.4 CDJ65848.1 - 0.02 15.3 0.2 0.055 13.9 0.2 1.7 1 0 0 1 1 1 0 Membrane magnesium transporter Urb2 PF10441.4 CDJ65848.1 - 0.62 9.6 5.3 0.18 11.3 1.5 1.5 1 1 0 1 1 1 0 Urb2/Npa2 family DUF2763 PF10961.3 CDJ65848.1 - 1.1 9.7 4.0 1.8 8.9 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF4614 PF15391.1 CDJ65849.1 - 4.9 6.8 8.9 8.7 6.0 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Cytochrom_B_N PF00033.14 CDJ65850.1 - 0.01 15.2 4.1 0.02 14.2 0.2 2.6 2 1 1 3 3 3 0 Cytochrome b(N-terminal)/b6/petB PCI_Csn8 PF10075.4 CDJ65851.1 - 3e-07 30.2 0.5 5.6e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CDJ65851.1 - 4.9e-07 29.5 0.2 7.8e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 CDJ65851.1 - 0.039 14.2 0.1 0.063 13.6 0.1 1.3 1 0 0 1 1 1 0 PCI domain NMDAR2_C PF10565.4 CDJ65851.1 - 0.23 10.1 3.3 2.3 6.7 0.1 2.1 2 0 0 2 2 2 0 N-methyl D-aspartate receptor 2B3 C-terminus APC_CDC26 PF10471.4 CDJ65851.1 - 2.1 9.1 10.8 7.4 7.3 0.9 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 SR-25 PF10500.4 CDJ65852.1 - 0.007 15.8 5.5 0.007 15.8 3.8 5.6 4 2 1 5 5 5 2 Nuclear RNA-splicing-associated protein EF-hand_6 PF13405.1 CDJ65852.1 - 0.057 13.3 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Spt20 PF12090.3 CDJ65854.1 - 0.021 14.1 12.0 0.29 10.4 2.2 2.3 2 0 0 2 2 2 0 Spt20 family Suf PF05843.9 CDJ65854.1 - 1 9.0 19.4 1.4 8.5 2.2 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 CDJ65854.1 - 2.4 5.7 11.6 2.3 5.8 2.8 2.0 2 0 0 2 2 2 0 Ycf1 Bud13 PF09736.4 CDJ65854.1 - 3.3 7.9 21.1 2.2 8.5 3.2 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Utp14 PF04615.8 CDJ65854.1 - 4.9 5.1 28.8 2.3 6.2 8.0 2.1 2 0 0 2 2 2 0 Utp14 protein BTV_NS2 PF04514.7 CDJ65854.1 - 5.1 5.8 11.6 4.4 6.0 3.6 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 MDM1 PF15501.1 CDJ65854.1 - 5.5 5.7 39.2 0.34 9.8 5.3 2.2 2 0 0 2 2 2 0 Nuclear protein MDM1 FimP PF09766.4 CDJ65854.1 - 5.5 5.9 29.6 0.91 8.5 5.8 2.4 2 0 0 2 2 2 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDJ65854.1 - 6.7 5.5 16.6 1.7 7.5 2.2 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Asp_protease_2 PF13650.1 CDJ65856.1 - 5.9e-07 29.8 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CDJ65856.1 - 1.5e-05 24.9 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CDJ65856.1 - 0.0002 21.1 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ65856.1 - 0.0012 18.6 0.0 0.0037 17.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3552 PF12072.3 CDJ65856.1 - 0.009 15.2 1.7 0.014 14.5 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Asp_protease PF09668.5 CDJ65856.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease rve PF00665.21 CDJ65857.1 - 4.1e-18 65.6 0.2 2.2e-16 60.0 0.0 2.5 2 1 0 2 2 2 2 Integrase core domain LRR_4 PF12799.2 CDJ65858.1 - 5e-40 134.4 35.3 5e-08 32.3 1.2 7.4 2 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ65858.1 - 1.6e-29 101.4 29.1 4.8e-09 35.8 0.7 4.8 3 1 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CDJ65858.1 - 1.2e-12 46.0 35.0 0.15 12.2 0.3 10.5 10 1 0 10 10 10 6 Leucine Rich Repeat LRR_6 PF13516.1 CDJ65858.1 - 9.6e-12 43.6 25.2 0.11 12.6 0.3 9.5 5 2 4 9 9 9 5 Leucine Rich repeat LRR_9 PF14580.1 CDJ65858.1 - 8.5e-11 41.7 16.3 0.00032 20.2 2.8 3.9 1 1 3 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 CDJ65858.1 - 1.5e-10 39.5 29.9 0.8 10.1 0.1 10.5 9 1 1 10 10 10 5 Leucine rich repeat RCC1 PF00415.13 CDJ65859.1 - 9.1e-28 96.2 11.3 1.9e-08 34.3 0.1 7.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ65859.1 - 2.9e-16 58.5 31.7 1.9e-06 27.3 3.2 6.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat zf-LITAF-like PF10601.4 CDJ65860.1 - 8.7e-15 54.3 5.3 8.7e-15 54.3 3.6 2.3 1 1 1 2 2 2 1 LITAF-like zinc ribbon domain Lung_7-TM_R PF06814.8 CDJ65861.1 - 0.00088 18.3 2.3 0.00098 18.1 1.0 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CDJ65861.1 - 0.0051 16.0 0.6 0.01 15.0 0.4 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain MIF4G PF02854.14 CDJ65862.1 - 3.3e-31 108.3 1.7 5.2e-31 107.6 1.1 1.3 1 0 0 1 1 1 1 MIF4G domain DUF3357 PF11837.3 CDJ65868.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Kinase-like PF14531.1 CDJ65869.1 - 1.4e-07 30.7 0.0 3.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDJ65869.1 - 0.0026 16.9 0.0 0.0071 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain DUF2360 PF10152.4 CDJ65869.1 - 3.2 8.0 13.1 0.057 13.6 1.5 2.8 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) WD40 PF00400.27 CDJ65870.1 - 1.4e-14 53.2 2.9 5.3e-11 41.9 0.0 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 CDJ65870.1 - 0.00022 19.4 1.5 0.0039 15.3 1.0 2.2 1 1 0 1 1 1 1 Nucleoporin Nup120/160 MMS1_N PF10433.4 CDJ65870.1 - 0.065 11.3 0.1 0.069 11.2 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4644 PF15486.1 CDJ65870.1 - 0.2 11.5 0.8 0.28 11.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) DUF1870 PF08965.5 CDJ65871.1 - 0.17 11.5 0.5 0.27 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) SR-25 PF10500.4 CDJ65871.1 - 0.23 10.8 23.8 0.34 10.3 16.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CDJ65871.1 - 1 7.5 15.4 1.1 7.4 10.7 1.0 1 0 0 1 1 1 0 Transmembrane protein MAP65_ASE1 PF03999.7 CDJ65871.1 - 1.4 7.4 8.1 1.6 7.2 5.6 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF566 PF04484.7 CDJ65871.1 - 1.8 7.9 17.9 2 7.8 12.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) CDC27 PF09507.5 CDJ65871.1 - 6.5 5.8 15.1 8.1 5.5 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4551 PF15087.1 CDJ65871.1 - 8.4 4.6 7.5 10 4.3 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DDRGK PF09756.4 CDJ65874.1 - 0.093 12.1 15.2 0.12 11.7 10.6 1.1 1 0 0 1 1 1 0 DDRGK domain Vfa1 PF08432.5 CDJ65874.1 - 0.29 11.1 9.7 0.38 10.7 6.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Herpes_env PF01673.13 CDJ65874.1 - 0.3 9.5 4.9 0.35 9.3 3.4 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Ycf1 PF05758.7 CDJ65874.1 - 0.7 7.5 7.5 0.77 7.3 5.2 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CDJ65874.1 - 0.98 7.3 9.1 1.2 7.1 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3513 PF12026.3 CDJ65874.1 - 1 8.8 8.0 1.2 8.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Daxx PF03344.10 CDJ65874.1 - 6.4 5.1 11.5 7.7 4.8 8.0 1.2 1 0 0 1 1 1 0 Daxx Family Ribosomal_L7Ae PF01248.21 CDJ65876.1 - 1.7e-28 97.9 0.6 2.2e-28 97.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.7 CDJ65876.1 - 0.0029 17.7 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Amastin PF07344.6 CDJ65877.1 - 0.013 15.0 25.8 0.083 12.5 8.4 2.9 2 1 1 3 3 3 0 Amastin surface glycoprotein zf-RING_2 PF13639.1 CDJ65879.1 - 2.1e-11 43.4 3.2 3.9e-11 42.5 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDJ65879.1 - 1.6e-08 34.4 3.3 2.9e-08 33.5 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDJ65879.1 - 3.5e-08 32.9 1.9 6.8e-08 32.0 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDJ65879.1 - 2.7e-07 30.6 1.9 6.1e-07 29.4 1.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CDJ65879.1 - 1.2e-06 28.0 4.9 2.4e-06 27.1 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ65879.1 - 1.4e-06 27.9 2.4 2.8e-06 26.9 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CDJ65879.1 - 0.00016 21.4 2.2 0.00016 21.4 1.6 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CDJ65879.1 - 0.0087 15.7 2.6 0.018 14.7 0.1 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CDJ65879.1 - 0.01 15.7 3.2 0.033 14.0 2.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CDJ65879.1 - 0.026 14.4 2.8 0.072 13.0 1.9 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CDJ65879.1 - 0.081 12.9 3.5 0.22 11.5 2.4 1.8 1 0 0 1 1 1 0 RING-variant domain zf-CCCH PF00642.19 CDJ65880.1 - 1.2e-09 37.6 15.0 0.00017 21.1 1.1 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAT1 PF09770.4 CDJ65880.1 - 4.2 5.4 52.7 0.48 8.5 21.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Chromo PF00385.19 CDJ65881.1 - 5.3e-07 29.2 0.1 1e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF566 PF04484.7 CDJ65881.1 - 3.6 7.0 13.0 8.5 5.7 9.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF566) HOOK PF05622.7 CDJ65882.1 - 0.0022 15.9 5.9 0.0023 15.8 4.1 1.0 1 0 0 1 1 1 1 HOOK protein CENP-F_leu_zip PF10473.4 CDJ65882.1 - 0.0032 17.3 7.0 0.0032 17.3 4.8 1.6 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CDJ65882.1 - 0.0094 15.4 5.7 0.011 15.2 3.9 1.0 1 0 0 1 1 1 1 Intermediate filament protein FEZ PF07763.8 CDJ65882.1 - 0.027 14.1 2.6 0.033 13.9 1.8 1.1 1 0 0 1 1 1 0 FEZ-like protein DUF848 PF05852.6 CDJ65882.1 - 0.19 11.5 4.7 0.14 11.9 1.1 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tropomyosin_1 PF12718.2 CDJ65882.1 - 0.26 11.1 8.7 0.32 10.8 6.0 1.2 1 0 0 1 1 1 0 Tropomyosin like CRF PF00473.12 CDJ65882.1 - 0.29 11.2 8.0 0.45 10.6 1.7 2.5 2 0 0 2 2 2 0 Corticotropin-releasing factor family IncA PF04156.9 CDJ65882.1 - 1.1 8.8 8.0 1.5 8.3 5.6 1.3 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 CDJ65883.1 - 0.0025 17.5 2.5 0.0044 16.7 1.7 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF1822 PF08852.6 CDJ65883.1 - 0.2 10.4 2.5 0.32 9.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Actino_peptide PF14408.1 CDJ65883.1 - 0.23 11.4 1.6 20 5.2 0.0 2.5 1 1 1 2 2 2 0 Ribosomally synthesized peptide in actinomycetes LCAT PF02450.10 CDJ65885.1 - 1.8e-26 93.0 0.0 1.7e-14 53.6 0.0 3.2 2 1 1 3 3 3 3 Lecithin:cholesterol acyltransferase DUF1500 PF07389.7 CDJ65885.1 - 0.085 12.8 0.1 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) FAM110_N PF14161.1 CDJ65885.1 - 0.15 12.3 1.6 2.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Centrosome-associated N terminus Chromo PF00385.19 CDJ65886.1 - 6.4e-07 28.9 0.0 1.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 CDJ65887.1 - 1.8e-17 63.3 0.1 2.5e-14 53.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65887.1 - 1.9e-09 37.0 0.0 2.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ65887.1 - 0.00011 21.3 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DNA_methylase PF00145.12 CDJ65888.1 - 6.6e-36 124.0 0.0 2.3e-34 119.0 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase FCP1_C PF09309.5 CDJ65888.1 - 1.6 8.0 13.4 0.16 11.2 0.5 2.3 2 0 0 2 2 2 0 FCP1, C-terminal ECIST_Cterm PF14784.1 CDJ65888.1 - 4.9 7.1 6.1 0.36 10.7 0.3 1.8 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein GAS PF13851.1 CDJ65889.1 - 1.8e-21 76.3 20.1 1.8e-21 76.3 13.9 2.6 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 CDJ65889.1 - 0.55 9.3 3.7 6 5.9 0.2 2.7 1 1 1 3 3 3 0 Reovirus sigma C capsid protein GRIM-19 PF06212.7 CDJ65889.1 - 0.66 9.6 4.3 2.5 7.8 3.0 2.0 1 0 0 1 1 1 0 GRIM-19 protein Spc7 PF08317.6 CDJ65889.1 - 2.5 6.7 44.8 0.71 8.4 11.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Spc97_Spc98 PF04130.8 CDJ65891.1 - 9.1e-36 123.2 1.1 9.1e-36 123.2 0.8 3.7 2 1 0 2 2 2 1 Spc97 / Spc98 family Ebola_NP PF05505.7 CDJ65893.1 - 0.97 7.4 16.9 1.2 7.1 11.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein PAT1 PF09770.4 CDJ65893.1 - 1.7 6.8 44.8 2.1 6.4 31.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.1 CDJ65893.1 - 2.2 7.1 12.3 3.7 6.4 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.12 CDJ65893.1 - 2.4 6.8 15.1 0.76 8.5 8.6 1.5 1 1 0 1 1 1 0 Presenilin TPR_2 PF07719.12 CDJ65894.1 - 0.012 15.4 0.5 0.012 15.4 0.4 9.5 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ65894.1 - 0.072 12.7 0.1 0.072 12.7 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Mem_trans PF03547.13 CDJ65895.1 - 9.3 4.4 9.9 0.59 8.3 1.4 2.5 2 0 0 2 2 2 0 Membrane transport protein SprA-related PF12118.3 CDJ65897.1 - 1.9e-05 24.1 29.9 2.1e-05 23.9 20.7 1.1 1 0 0 1 1 1 1 SprA-related family Med15 PF09606.5 CDJ65897.1 - 0.00097 17.4 42.7 0.00097 17.4 29.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ65897.1 - 0.0029 15.9 35.9 0.003 15.9 24.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDJ65897.1 - 0.0036 17.3 23.0 0.0063 16.5 15.9 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.8 CDJ65897.1 - 0.0082 16.0 25.9 0.0088 15.9 17.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.5 CDJ65897.1 - 0.012 15.5 17.1 0.016 15.2 11.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Suf PF05843.9 CDJ65897.1 - 0.013 15.2 19.7 0.017 14.8 13.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3408 PF11888.3 CDJ65897.1 - 0.016 15.1 15.2 0.026 14.4 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) AIF_C PF14721.1 CDJ65897.1 - 0.023 14.9 10.4 0.031 14.5 7.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF605 PF04652.11 CDJ65897.1 - 0.027 13.9 22.9 0.028 13.8 15.9 1.1 1 0 0 1 1 1 0 Vta1 like Raftlin PF15250.1 CDJ65897.1 - 0.028 12.9 10.9 0.031 12.8 7.5 1.1 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.7 CDJ65897.1 - 0.032 14.1 15.0 0.036 13.9 10.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDJ65897.1 - 0.053 13.3 13.3 0.061 13.1 9.2 1.1 1 0 0 1 1 1 0 DDHD domain MMR1 PF08505.5 CDJ65897.1 - 0.064 13.2 16.1 0.083 12.9 11.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF1764 PF08576.5 CDJ65897.1 - 0.071 13.8 15.7 0.12 13.2 10.9 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CT47 PF15623.1 CDJ65897.1 - 0.09 12.5 18.8 0.1 12.2 13.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 SAGA-Tad1 PF12767.2 CDJ65897.1 - 0.095 12.3 17.9 0.11 12.1 12.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Zip PF02535.17 CDJ65897.1 - 0.1 11.5 4.6 0.12 11.3 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1675 PF07897.6 CDJ65897.1 - 0.12 12.1 7.8 0.16 11.8 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) AAA_23 PF13476.1 CDJ65897.1 - 0.16 12.2 18.2 0.18 12.0 12.6 1.1 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.6 CDJ65897.1 - 0.16 10.1 15.8 0.16 10.1 10.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4557 PF15101.1 CDJ65897.1 - 0.2 11.5 28.9 0.25 11.1 20.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FimP PF09766.4 CDJ65897.1 - 0.2 10.7 28.4 0.26 10.3 19.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein Ndc1_Nup PF09531.5 CDJ65897.1 - 0.21 9.9 10.6 0.21 9.9 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AUX_IAA PF02309.11 CDJ65897.1 - 0.31 10.7 13.2 0.38 10.4 9.1 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4175 PF13779.1 CDJ65897.1 - 0.37 8.4 45.1 0.44 8.1 31.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Rtf2 PF04641.7 CDJ65897.1 - 0.4 9.8 19.9 0.51 9.4 13.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Plasmodium_Vir PF05795.6 CDJ65897.1 - 0.4 9.8 4.3 0.42 9.7 3.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4011 PF13195.1 CDJ65897.1 - 0.46 10.4 11.7 0.68 9.9 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Spore_coat_CotO PF14153.1 CDJ65897.1 - 0.48 9.8 24.0 0.59 9.5 16.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF3292 PF11696.3 CDJ65897.1 - 0.48 8.2 6.0 0.62 7.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF853 PF05872.7 CDJ65897.1 - 0.51 8.6 14.3 0.71 8.1 9.9 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AFT PF08731.6 CDJ65897.1 - 0.57 10.3 9.7 0.84 9.8 6.8 1.3 1 0 0 1 1 1 0 Transcription factor AFT eIF-3_zeta PF05091.7 CDJ65897.1 - 0.66 8.5 21.7 0.76 8.3 15.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SeqA PF03925.8 CDJ65897.1 - 1 9.0 13.0 1.4 8.5 9.0 1.3 1 0 0 1 1 1 0 SeqA protein FLO_LFY PF01698.11 CDJ65897.1 - 1.2 7.8 15.1 1.5 7.6 10.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SpoVR PF04293.8 CDJ65897.1 - 1.3 7.3 14.9 1.5 7.0 10.4 1.1 1 0 0 1 1 1 0 SpoVR like protein CDC45 PF02724.9 CDJ65897.1 - 1.3 6.9 16.7 1.5 6.7 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDJ65897.1 - 1.6 6.3 17.0 1.9 6.1 11.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 CDJ65897.1 - 1.7 8.3 15.1 2.1 8.0 10.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A UPF0560 PF10577.4 CDJ65897.1 - 1.7 6.7 23.8 2.2 6.4 16.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CPSF100_C PF13299.1 CDJ65897.1 - 1.8 8.7 13.0 2.5 8.2 9.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Dala_Dala_lig_N PF01820.16 CDJ65897.1 - 1.8 8.8 7.3 3.4 8.0 5.1 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Herpes_DNAp_acc PF04929.7 CDJ65897.1 - 2.1 7.2 14.4 2.4 7.0 10.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Band_3_cyto PF07565.8 CDJ65897.1 - 2.3 7.6 17.1 2.9 7.3 11.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gag_spuma PF03276.9 CDJ65897.1 - 2.5 6.3 35.5 3 6.0 24.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF4220 PF13968.1 CDJ65897.1 - 2.7 6.9 7.1 3.2 6.7 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) RIC3 PF15361.1 CDJ65897.1 - 2.8 8.1 18.7 5 7.3 13.0 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Paf1 PF03985.8 CDJ65897.1 - 3.1 6.4 22.4 3.8 6.1 15.5 1.1 1 0 0 1 1 1 0 Paf1 Ycf1 PF05758.7 CDJ65897.1 - 3.1 5.3 18.5 3.3 5.3 12.8 1.0 1 0 0 1 1 1 0 Ycf1 DHHW PF14286.1 CDJ65897.1 - 3.3 6.9 13.9 4 6.6 9.6 1.1 1 0 0 1 1 1 0 DHHW protein NPR3 PF03666.8 CDJ65897.1 - 4.1 5.8 16.8 5.3 5.4 11.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cellulose_synt PF03552.9 CDJ65897.1 - 4.2 5.5 7.3 5.1 5.2 5.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Gti1_Pac2 PF09729.4 CDJ65897.1 - 4.3 7.1 12.8 6.1 6.6 8.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Neur_chan_memb PF02932.11 CDJ65897.1 - 4.3 7.1 11.7 5.5 6.8 8.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 CDJ65897.1 - 4.7 5.6 10.8 5.9 5.2 7.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier Baculo_PP31 PF05311.6 CDJ65897.1 - 4.7 6.3 17.8 6.2 6.0 12.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Glyco_transf_15 PF01793.11 CDJ65897.1 - 5.2 5.9 16.2 5.9 5.7 11.2 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PBP1_TM PF14812.1 CDJ65897.1 - 5.3 7.4 11.6 5.9 7.2 7.3 1.7 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CMV_1a PF12467.3 CDJ65897.1 - 5.8 7.2 14.3 8 6.8 9.9 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF1800 PF08811.6 CDJ65897.1 - 5.9 5.6 23.8 7.5 5.3 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DUF3675 PF12428.3 CDJ65897.1 - 6.4 7.0 10.4 11 6.3 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF3708 PF12501.3 CDJ65897.1 - 6.7 6.5 6.1 9.9 5.9 4.3 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter NARP1 PF12569.3 CDJ65897.1 - 6.9 5.3 21.2 8.9 4.9 14.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EIIBC-GUT_N PF03612.9 CDJ65897.1 - 7.2 6.1 12.7 11 5.6 8.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Paramyxo_ncap PF00973.14 CDJ65897.1 - 8.2 4.9 13.3 9.8 4.7 9.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein APG6 PF04111.7 CDJ65897.1 - 8.7 5.2 20.7 10 5.0 14.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3260 PF11658.3 CDJ65897.1 - 8.8 4.3 14.5 10 4.0 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) FAM176 PF14851.1 CDJ65897.1 - 9 5.9 10.1 14 5.3 7.0 1.3 1 0 0 1 1 1 0 FAM176 family DEC-1_N PF04625.8 CDJ65898.1 - 1.5 7.3 7.4 1.6 7.3 5.1 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ASFV_J13L PF05568.6 CDJ65898.1 - 1.9 8.0 4.8 1.9 7.9 3.3 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein PsbQ PF05757.6 CDJ65898.1 - 2.3 7.5 4.8 2.6 7.4 3.3 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) SseC PF04888.7 CDJ65898.1 - 3.9 6.7 14.8 4.3 6.5 10.3 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Thioredoxin PF00085.15 CDJ65899.1 - 3.1e-44 148.9 0.3 9.6e-21 73.4 0.5 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 CDJ65899.1 - 4.1e-11 42.8 0.1 0.00069 19.6 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CDJ65899.1 - 7.6e-10 38.6 0.9 0.00023 21.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CDJ65899.1 - 1.2e-08 34.5 0.3 0.00036 20.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CDJ65899.1 - 3.6e-06 27.1 7.4 0.017 15.3 0.1 3.8 3 1 0 3 3 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CDJ65899.1 - 1.9e-05 24.3 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.5 CDJ65899.1 - 0.00013 21.5 0.1 0.011 15.2 0.0 2.3 2 0 0 2 2 2 1 Redoxin Thioredoxin_6 PF13848.1 CDJ65899.1 - 0.00014 21.7 0.0 0.001 18.8 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain DUF2946 PF11162.3 CDJ65899.1 - 0.00018 21.6 4.6 0.064 13.4 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2946) Med15 PF09606.5 CDJ65899.1 - 0.0014 16.9 12.8 0.0015 16.8 8.9 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDJ65899.1 - 0.0033 17.4 11.7 0.071 13.1 2.8 2.2 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.3 CDJ65899.1 - 0.0059 16.2 8.3 0.0059 16.2 5.7 2.2 2 0 0 2 2 2 1 Period protein 2/3C-terminal region Corona_nucleoca PF00937.13 CDJ65899.1 - 0.0066 15.4 1.1 0.0066 15.4 0.8 2.1 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein IL2 PF00715.12 CDJ65899.1 - 0.011 15.4 2.0 0.15 11.8 0.0 2.6 2 1 1 3 3 3 0 Interleukin 2 DUF4614 PF15391.1 CDJ65899.1 - 0.017 14.8 8.5 0.057 13.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) MsyB PF13984.1 CDJ65899.1 - 0.026 14.5 1.8 0.044 13.8 0.0 2.1 2 0 0 2 2 2 0 MsyB protein Ndc1_Nup PF09531.5 CDJ65899.1 - 0.032 12.6 3.3 0.041 12.3 2.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Myco_19_kDa PF05481.7 CDJ65899.1 - 0.17 11.6 4.2 0.3 10.8 2.9 1.3 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen DDHD PF02862.12 CDJ65899.1 - 0.29 10.9 9.0 0.62 9.8 0.1 2.1 2 0 0 2 2 2 0 DDHD domain SR-25 PF10500.4 CDJ65899.1 - 0.31 10.4 28.2 0.093 12.1 10.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ctr PF04145.10 CDJ65899.1 - 0.51 10.3 2.6 2.9 7.9 0.4 2.1 2 0 0 2 2 2 0 Ctr copper transporter family DDE_Tnp_1_2 PF13586.1 CDJ65899.1 - 0.57 10.3 6.1 74 3.6 0.0 3.3 2 1 0 2 2 2 0 Transposase DDE domain SSP160 PF06933.6 CDJ65899.1 - 0.97 7.3 10.5 1.2 6.9 7.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Band_3_cyto PF07565.8 CDJ65899.1 - 1.5 8.2 5.2 2.3 7.6 1.1 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FAM60A PF15396.1 CDJ65899.1 - 1.6 8.3 10.9 0.59 9.8 0.6 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Spt20 PF12090.3 CDJ65899.1 - 2.3 7.5 10.1 1.6 8.0 5.1 1.8 2 0 0 2 2 2 0 Spt20 family AIF_C PF14721.1 CDJ65899.1 - 2.5 8.3 7.6 23 5.2 0.1 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TUSC2 PF15000.1 CDJ65899.1 - 3.1 7.9 7.3 3 7.9 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor candidate 2 RAP1 PF07218.6 CDJ65899.1 - 8.1 4.4 10.3 9.9 4.1 7.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LUC7 PF03194.10 CDJ65900.1 - 1.5e-33 116.3 0.8 1.5e-33 116.3 0.5 2.4 1 1 1 2 2 2 1 LUC7 N_terminus RabGAP-TBC PF00566.13 CDJ65901.1 - 9.1e-18 64.5 0.0 1.1e-17 64.2 0.0 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Antimicrobial14 PF08109.6 CDJ65901.1 - 0.075 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Lactocin 705 family DUF3446 PF11928.3 CDJ65902.1 - 0.43 10.8 6.2 0.69 10.1 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 CDJ65902.1 - 4.2 6.7 14.7 6.6 6.1 10.2 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.1 CDJ65902.1 - 5.1 5.9 15.2 5.9 5.7 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RskA PF10099.4 CDJ65902.1 - 6.4 6.4 14.5 9.9 5.8 10.1 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA N_NLPC_P60 PF12912.2 CDJ65902.1 - 7.3 6.7 12.4 12 6.0 8.6 1.5 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term MTBP_C PF14920.1 CDJ65902.1 - 7.3 6.0 11.3 8.1 5.8 7.8 1.0 1 0 0 1 1 1 0 MDM2-binding Corona_S2 PF01601.11 CDJ65904.1 - 3.4 5.6 6.1 3.7 5.5 4.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Peptidase_C50 PF03568.12 CDJ65905.1 - 0.27 9.8 4.1 0.33 9.5 2.8 1.0 1 0 0 1 1 1 0 Peptidase family C50 RAB3GAP2_N PF14655.1 CDJ65905.1 - 0.31 10.0 5.2 0.056 12.4 1.0 1.5 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1525 PF07511.6 CDJ65905.1 - 1.1 9.3 13.5 2.7 8.0 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1525) ERF PF04404.7 CDJ65905.1 - 4.6 6.7 16.2 13 5.3 0.2 2.1 2 0 0 2 2 2 0 ERF superfamily FlxA PF14282.1 CDJ65905.1 - 8 6.4 30.8 6.2 6.8 7.2 2.3 2 0 0 2 2 2 0 FlxA-like protein zf-RanBP PF00641.13 CDJ65906.1 - 4.5e-06 25.6 6.6 6.4e-06 25.1 4.6 1.2 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Med15 PF09606.5 CDJ65906.1 - 0.0012 17.1 11.7 0.0014 16.9 8.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ65906.1 - 0.023 14.0 2.0 0.028 13.7 1.4 1.2 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.3 CDJ65906.1 - 5.9 5.5 25.1 9.5 4.8 17.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAT1 PF09770.4 CDJ65906.1 - 7.3 4.7 22.9 8.6 4.4 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Filo_glycop PF01611.11 CDJ65907.1 - 0.52 9.0 5.3 0.81 8.4 3.7 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein Spt20 PF12090.3 CDJ65907.1 - 0.91 8.8 14.3 0.53 9.6 5.0 2.3 2 0 0 2 2 2 0 Spt20 family Ycf1 PF05758.7 CDJ65907.1 - 4.8 4.7 11.0 5.6 4.5 7.6 1.1 1 0 0 1 1 1 0 Ycf1 Peptidase_U57 PF05582.7 CDJ65907.1 - 8.1 5.3 7.6 13 4.6 5.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF3141 PF11339.3 CDJ65908.1 - 0.15 10.3 4.7 0.17 10.1 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DivIC PF04977.10 CDJ65908.1 - 0.22 11.0 17.6 0.15 11.5 4.4 2.1 2 0 0 2 2 2 0 Septum formation initiator FAM60A PF15396.1 CDJ65908.1 - 0.47 10.1 6.7 0.56 9.9 4.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF4647 PF15504.1 CDJ65908.1 - 1 8.1 14.9 1.2 7.9 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) AAA_23 PF13476.1 CDJ65908.1 - 1.6 9.0 5.7 2.2 8.5 3.9 1.2 1 0 0 1 1 1 0 AAA domain DUF2407_C PF13373.1 CDJ65908.1 - 2 8.3 5.5 2.6 7.9 3.8 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain APC_CDC26 PF10471.4 CDJ65908.1 - 2.1 9.1 28.2 0.89 10.3 6.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF2868 PF11067.3 CDJ65908.1 - 2.4 7.2 11.9 2.6 7.1 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF4551 PF15087.1 CDJ65908.1 - 3 6.1 6.5 3.4 5.9 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) VIT PF08487.5 CDJ65908.1 - 5.1 6.8 8.9 5.4 6.7 0.3 2.1 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain eIF-3_zeta PF05091.7 CDJ65908.1 - 5.6 5.4 13.4 7.6 5.0 9.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WWbp PF10349.4 CDJ65908.1 - 6.5 7.6 13.6 8.6 7.2 9.4 1.2 1 0 0 1 1 1 0 WW-domain ligand protein Dynamin_N PF00350.18 CDJ65908.1 - 6.8 6.4 8.0 22 4.8 5.6 1.8 1 1 0 1 1 1 0 Dynamin family DUF4407 PF14362.1 CDJ65908.1 - 7.8 5.3 14.1 9.2 5.1 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PHD_3 PF13922.1 CDJ65908.1 - 9 6.6 20.4 10 6.4 5.2 2.1 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Mpv17_PMP22 PF04117.7 CDJ65912.1 - 5e-14 51.6 2.2 5.8e-14 51.4 0.1 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Herpes_DNAp_acc PF04929.7 CDJ65912.1 - 7.1 5.4 9.7 6.6 5.5 0.7 2.4 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Kelch_6 PF13964.1 CDJ65913.1 - 6.7e-06 26.0 0.5 0.0009 19.3 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CDJ65913.1 - 1.7e-05 24.4 0.1 6.3e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_3 PF13415.1 CDJ65913.1 - 6.6e-05 22.9 0.3 0.008 16.3 0.0 4.0 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ65913.1 - 0.00011 21.9 0.1 0.011 15.6 0.0 2.8 3 0 0 3 3 3 1 Kelch motif PAM2 PF07145.10 CDJ65913.1 - 0.0071 15.7 0.3 0.015 14.7 0.2 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Kelch_1 PF01344.20 CDJ65913.1 - 0.19 11.2 0.0 0.46 10.0 0.0 1.7 1 0 0 1 1 1 0 Kelch motif PIG-H PF10181.4 CDJ65914.1 - 2.6e-12 46.1 0.1 5.1e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component RNA_pol_Rpb1_5 PF04998.12 CDJ65915.1 - 3.6e-100 334.7 0.2 5.6e-100 334.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CDJ65915.1 - 1.8e-96 323.3 0.0 4.2e-96 322.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CDJ65915.1 - 1.8e-68 229.7 0.0 4.2e-68 228.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_7 PF04990.7 CDJ65915.1 - 6.5e-44 148.9 1.6 1.3e-43 147.9 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 CDJ65915.1 - 6.6e-44 149.4 0.0 2e-43 147.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_6 PF04992.9 CDJ65915.1 - 8.5e-43 146.2 3.5 1.6e-42 145.4 2.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.12 CDJ65915.1 - 4.3e-39 132.6 0.2 4.3e-39 132.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 LSM PF01423.17 CDJ65916.1 - 1.5e-14 53.2 0.3 1.8e-14 53.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain RCC1 PF00415.13 CDJ65917.1 - 2.5e-32 110.8 11.4 1e-08 35.2 0.2 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ65917.1 - 1.5e-16 59.5 17.8 2e-06 27.2 0.1 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat UQ_con PF00179.21 CDJ65918.1 - 5.7e-44 148.9 0.0 7.5e-44 148.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 CDJ65918.1 - 3.6e-09 36.1 0.1 6.1e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.1 CDJ65918.1 - 0.0036 17.0 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CDJ65918.1 - 0.0059 16.4 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 RWD domain UCR_14kD PF02271.11 CDJ65920.1 - 5.9e-16 58.1 0.2 8.1e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SR-25 PF10500.4 CDJ65920.1 - 3.7 6.9 9.0 5.2 6.4 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rsm22 PF09243.5 CDJ65921.1 - 3.5e-52 177.1 10.7 2.9e-34 118.3 0.2 4.0 4 1 0 4 4 4 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 CDJ65921.1 - 2.4e-06 28.1 1.1 6.8e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ65921.1 - 4.2e-06 26.5 0.0 9.9e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ65921.1 - 0.0014 19.0 0.0 0.0044 17.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ65921.1 - 0.0036 17.7 0.0 0.013 15.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Med15 PF09606.5 CDJ65921.1 - 0.0079 14.4 0.4 0.0079 14.4 0.3 3.7 4 0 0 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_UL31 PF02718.9 CDJ65921.1 - 0.35 9.5 1.3 0.68 8.5 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL31-like protein zf-Tim10_DDP PF02953.10 CDJ65922.1 - 4.9e-08 32.1 3.1 2.3e-07 29.9 2.2 1.9 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CDJ65922.1 - 0.076 12.4 0.4 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Ribosomal_60s PF00428.14 CDJ65922.1 - 0.15 12.4 13.3 0.25 11.7 9.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SURF2 PF05477.6 CDJ65923.1 - 0.0032 16.6 3.4 0.0032 16.6 2.3 2.4 3 0 0 3 3 3 1 Surfeit locus protein 2 (SURF2) DinI PF06183.8 CDJ65924.1 - 0.056 13.4 0.2 0.41 10.7 0.1 2.1 2 0 0 2 2 2 0 DinI-like family SR-25 PF10500.4 CDJ65924.1 - 0.48 9.8 59.2 0.011 15.2 15.1 3.0 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Apc3 PF12895.2 CDJ65925.1 - 8.3e-06 25.8 9.7 0.0087 16.1 0.9 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CDJ65925.1 - 6e-05 22.5 3.0 0.034 13.9 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Dicty_REP PF05086.7 CDJ65925.1 - 0.0017 16.2 14.4 0.0028 15.5 10.0 1.3 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein TPR_6 PF13174.1 CDJ65925.1 - 0.029 14.8 13.6 0.71 10.4 0.0 6.0 5 1 0 5 5 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 CDJ65925.1 - 0.45 10.9 2.2 9.8 6.7 0.0 4.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain LMBR1 PF04791.11 CDJ65925.1 - 9.7 4.6 8.2 15 4.0 5.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Cwf_Cwc_15 PF04889.7 CDJ65926.1 - 0.0092 15.7 24.1 0.011 15.4 16.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 CDJ65926.1 - 0.018 15.3 7.9 0.018 15.3 5.5 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CD20 PF04103.10 CDJ65926.1 - 0.018 14.9 2.1 0.018 14.9 1.5 2.2 2 0 0 2 2 2 0 CD20-like family DUF2228 PF10228.4 CDJ65926.1 - 0.19 11.2 11.2 0.26 10.8 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) PRCC PF10253.4 CDJ65926.1 - 0.3 11.7 35.5 0.1 13.3 3.7 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3675 PF12428.3 CDJ65926.1 - 1.3 9.2 15.7 0.032 14.4 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Herpes_env PF01673.13 CDJ65926.1 - 1.8 7.0 16.6 2.2 6.7 11.5 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SAPS PF04499.10 CDJ65926.1 - 2.1 6.8 20.6 2.7 6.5 14.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FimP PF09766.4 CDJ65926.1 - 3 6.8 47.9 0.074 12.1 19.1 2.3 2 0 0 2 2 2 0 Fms-interacting protein Herpes_UL87 PF03043.9 CDJ65926.1 - 3.7 5.8 13.0 4.3 5.6 9.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Peroxin-13_N PF04088.8 CDJ65926.1 - 3.9 7.4 22.2 0.026 14.4 6.7 2.4 2 1 0 2 2 2 0 Peroxin 13, N-terminal region SR-25 PF10500.4 CDJ65926.1 - 6.1 6.2 27.0 0.092 12.1 8.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_M56 PF05569.6 CDJ65926.1 - 6.4 5.6 8.7 9.1 5.1 6.0 1.3 1 1 0 1 1 1 0 BlaR1 peptidase M56 Sporozoite_P67 PF05642.6 CDJ65927.1 - 0.93 7.2 4.7 1.2 6.9 3.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 CDJ65929.1 - 5.2e-09 35.6 0.8 0.00017 21.2 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF4207 PF13904.1 CDJ65929.1 - 0.0028 17.0 0.6 0.004 16.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) DUF2853 PF11015.3 CDJ65929.1 - 0.0036 17.7 0.1 0.0066 16.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2853) Corona_nucleoca PF00937.13 CDJ65929.1 - 0.02 13.8 1.3 0.029 13.3 0.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Sec3_C PF09763.4 CDJ65929.1 - 0.13 10.3 2.5 0.17 9.9 1.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 RAP1 PF07218.6 CDJ65929.1 - 0.25 9.4 4.6 0.33 9.0 3.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Aminotran_3 PF00202.16 CDJ65929.1 - 0.26 10.1 4.3 0.43 9.3 1.2 2.4 2 1 1 3 3 3 0 Aminotransferase class-III LisH PF08513.6 CDJ65930.1 - 0.0002 20.9 0.2 0.00057 19.5 0.1 1.9 1 0 0 1 1 1 1 LisH GSK-3_bind PF05350.7 CDJ65930.1 - 0.00024 20.6 6.3 0.00044 19.7 4.4 1.4 1 0 0 1 1 1 1 Glycogen synthase kinase-3 binding DREPP PF05558.7 CDJ65930.1 - 4.6 7.0 9.4 4.2 7.1 4.0 2.0 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide DUF4339 PF14237.1 CDJ65931.1 - 0.032 13.8 0.3 0.032 13.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) UPF0565 PF10561.4 CDJ65931.1 - 1.4 7.7 4.5 1.4 7.7 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 SR-25 PF10500.4 CDJ65932.1 - 0.0013 18.3 20.7 0.0013 18.3 14.3 5.1 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein IF-2B PF01008.12 CDJ65933.1 - 7.2e-11 41.5 2.2 7.2e-11 41.5 1.5 2.5 2 1 0 2 2 2 1 Initiation factor 2 subunit family DAN PF03045.10 CDJ65933.1 - 0.069 12.5 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 DAN domain DUF3649 PF12365.3 CDJ65934.1 - 3.5 7.2 9.3 0.085 12.3 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Ribosomal_S13_N PF08069.7 CDJ65935.1 - 2.4e-26 91.3 0.1 4.9e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CDJ65935.1 - 3.7e-22 77.8 0.2 5.9e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 HTH_32 PF13565.1 CDJ65935.1 - 0.027 15.2 0.0 0.057 14.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain CRAL_TRIO PF00650.15 CDJ65936.1 - 1.7e-18 66.6 0.0 3.3e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CDJ65936.1 - 2.8e-07 30.5 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain LMBR1 PF04791.11 CDJ65937.1 - 5.2 5.5 7.7 12 4.2 2.3 2.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Drc1-Sld2 PF11719.3 CDJ65938.1 - 0.034 13.2 6.2 0.037 13.1 4.3 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein ATG16 PF08614.6 CDJ65938.1 - 0.19 11.5 17.2 0.25 11.1 11.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Vfa1 PF08432.5 CDJ65938.1 - 0.67 9.9 6.2 0.99 9.3 4.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Occludin_ELL PF07303.8 CDJ65938.1 - 2.1 9.1 6.0 13 6.5 0.4 2.3 2 0 0 2 2 2 0 Occludin homology domain FMN_red PF03358.10 CDJ65938.1 - 2.5 7.6 4.9 0.73 9.3 0.7 2.1 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Sulfatase_C PF14707.1 CDJ65938.1 - 6.8 6.9 9.0 3.5 7.9 3.3 2.2 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase ThiF PF00899.16 CDJ65939.1 - 2.5e-25 88.8 0.4 1.3e-19 70.3 0.2 2.6 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.4 CDJ65939.1 - 5.3e-14 51.3 1.6 1.3e-13 50.1 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CDJ65939.1 - 2.6e-11 43.4 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 CDJ65939.1 - 5.2e-11 41.9 0.5 1.7e-10 40.3 0.4 1.9 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein SR-25 PF10500.4 CDJ65939.1 - 2.2e-05 24.0 18.2 2.2e-05 24.0 12.6 6.1 4 2 0 4 4 2 1 Nuclear RNA-splicing-associated protein OmpH PF03938.9 CDJ65939.1 - 0.00013 21.9 6.9 0.00013 21.9 4.8 4.1 3 1 1 4 4 2 1 Outer membrane protein (OmpH-like) Shikimate_DH PF01488.15 CDJ65939.1 - 0.012 15.7 0.2 0.032 14.3 0.0 1.7 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CDJ65939.1 - 0.19 12.1 0.3 0.42 11.0 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CDJ65939.1 - 0.19 11.7 2.6 0.49 10.4 0.6 2.4 1 1 1 2 2 2 0 TrkA-N domain COX6A PF02046.10 CDJ65939.1 - 0.27 11.1 4.9 0.89 9.4 3.4 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa LUC7 PF03194.10 CDJ65939.1 - 0.39 10.2 13.4 1 8.8 9.3 1.6 1 0 0 1 1 1 0 LUC7 N_terminus Polysacc_synt_2 PF02719.10 CDJ65939.1 - 0.52 9.1 0.0 0.52 9.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AAA_23 PF13476.1 CDJ65939.1 - 2.2 8.5 19.9 0.2 11.9 9.5 2.1 2 0 0 2 2 2 0 AAA domain DUF808 PF05661.7 CDJ65939.1 - 4.8 5.9 7.9 0.3 9.8 1.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF808) UPF0233 PF06781.7 CDJ65939.1 - 8 6.1 9.1 12 5.6 0.5 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Choline_kinase PF01633.15 CDJ65940.1 - 3.5e-32 111.7 0.0 1.8e-31 109.4 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 CDJ65940.1 - 2.6e-15 56.8 0.0 2.6e-15 56.8 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family GCOM2 PF15328.1 CDJ65940.1 - 0.0016 18.2 6.1 0.0028 17.4 4.2 1.4 1 0 0 1 1 1 1 Putative GRINL1B complex locus protein 2 EcKinase PF02958.15 CDJ65940.1 - 0.0048 16.0 0.3 0.013 14.6 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase DUF457 PF04307.9 CDJ65940.1 - 0.11 11.8 3.1 5.9 6.2 0.7 2.4 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Ctr PF04145.10 CDJ65940.1 - 1.9 8.4 7.6 1.1 9.2 1.9 2.3 2 0 0 2 2 2 0 Ctr copper transporter family FimP PF09766.4 CDJ65940.1 - 2.8 6.9 13.5 0.2 10.7 5.9 1.5 2 0 0 2 2 2 0 Fms-interacting protein CDK5_activator PF03261.10 CDJ65940.1 - 7.7 5.7 10.0 12 5.0 7.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Presenilin PF01080.12 CDJ65940.1 - 9.9 4.8 7.2 15 4.3 5.0 1.3 1 0 0 1 1 1 0 Presenilin SAGA-Tad1 PF12767.2 CDJ65941.1 - 0.0045 16.6 3.3 0.0045 16.6 2.3 2.1 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit DUF788 PF05620.6 CDJ65941.1 - 0.035 13.9 1.9 0.035 13.9 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Activator_LAG-3 PF11498.3 CDJ65941.1 - 0.056 12.1 33.0 0.078 11.7 6.3 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Med31 PF05669.7 CDJ65941.1 - 0.75 9.5 5.1 0.13 12.0 0.5 1.8 2 0 0 2 2 2 0 SOH1 Pap_E4 PF02711.9 CDJ65941.1 - 1.9 9.3 11.5 1.3 9.8 1.7 2.2 2 0 0 2 2 2 0 E4 protein SARG PF15385.1 CDJ65941.1 - 2.9 7.1 21.2 10 5.3 14.7 1.8 1 1 0 1 1 1 0 Specifically androgen-regulated gene protein Cytochrom_C_asm PF01578.15 CDJ65943.1 - 0.81 9.1 3.7 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C assembly protein RRN3 PF05327.6 CDJ65944.1 - 9.8e-23 80.0 0.4 1.2e-22 79.8 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF1539 PF07560.6 CDJ65944.1 - 0.039 13.8 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) NAD_binding_4 PF07993.7 CDJ65944.1 - 0.041 12.8 0.1 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Ycf1 PF05758.7 CDJ65945.1 - 0.71 7.5 13.0 0.75 7.4 9.0 1.2 1 0 0 1 1 1 0 Ycf1 Utp14 PF04615.8 CDJ65945.1 - 4.2 5.4 41.9 5.6 4.9 29.0 1.1 1 0 0 1 1 1 0 Utp14 protein MIP-T3 PF10243.4 CDJ65945.1 - 7.3 4.9 50.5 12 4.1 35.0 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 CDJ65947.1 - 1.9e-06 25.9 5.4 2.4e-06 25.6 3.7 1.0 1 0 0 1 1 1 1 Ycf1 RRM_5 PF13893.1 CDJ65947.1 - 0.083 12.7 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_UL87 PF03043.9 CDJ65947.1 - 0.087 11.2 6.4 0.093 11.0 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Hid1 PF12722.2 CDJ65947.1 - 0.23 9.0 20.7 1.8 6.1 13.9 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein MMR1 PF08505.5 CDJ65947.1 - 0.29 11.1 26.9 0.63 10.0 18.7 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DDHD PF02862.12 CDJ65947.1 - 0.51 10.0 20.3 0.75 9.5 14.1 1.1 1 0 0 1 1 1 0 DDHD domain YfhO PF09586.5 CDJ65947.1 - 3.2 5.6 13.0 3.9 5.3 9.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PAT1 PF09770.4 CDJ65947.1 - 4.8 5.2 55.5 6.3 4.8 38.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FliP PF00813.15 CDJ65947.1 - 6.1 6.5 13.4 9.8 5.8 9.3 1.3 1 0 0 1 1 1 0 FliP family Pkinase PF00069.20 CDJ65948.1 - 1.8e-52 178.0 0.1 2.3e-48 164.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ65948.1 - 1.9e-29 102.5 0.1 4.2e-29 101.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ65948.1 - 0.00061 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SOBP PF15279.1 CDJ65948.1 - 0.00084 19.8 2.5 0.0013 19.1 1.8 1.3 1 0 0 1 1 1 1 Sine oculis-binding protein Sec3_C PF09763.4 CDJ65948.1 - 0.01 14.0 0.1 0.017 13.2 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 HemX PF04375.9 CDJ65948.1 - 0.07 11.7 7.9 0.13 10.7 5.5 1.4 1 1 0 1 1 1 0 HemX APH PF01636.18 CDJ65948.1 - 0.11 12.2 2.7 0.46 10.1 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pex14_N PF04695.8 CDJ65948.1 - 0.3 11.1 9.8 4.6 7.2 3.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF566 PF04484.7 CDJ65948.1 - 0.41 10.0 10.2 0.68 9.3 7.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) dsDNA_bind PF01984.15 CDJ65948.1 - 0.53 10.3 10.0 0.22 11.5 4.3 2.1 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Apt1 PF10351.4 CDJ65948.1 - 1.2 7.9 6.1 1.9 7.2 4.2 1.4 1 1 0 1 1 1 0 Golgi-body localisation protein domain SipA PF09052.5 CDJ65948.1 - 1.5 7.1 7.1 2.2 6.5 4.9 1.2 1 0 0 1 1 1 0 Salmonella invasion protein A SR-25 PF10500.4 CDJ65948.1 - 5.3 6.4 24.6 0.46 9.9 13.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.6 CDJ65948.1 - 7.2 4.3 9.0 10 3.8 6.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PT PF04886.7 CDJ65949.1 - 0.00051 19.3 37.3 0.002 17.4 11.4 9.7 5 3 3 8 8 8 3 PT repeat Sporozoite_P67 PF05642.6 CDJ65949.1 - 0.00059 17.8 0.0 0.00059 17.8 0.0 2.6 1 1 1 2 2 2 1 Sporozoite P67 surface antigen Ebp2 PF05890.7 CDJ65951.1 - 1e-30 107.0 14.7 1.6e-30 106.3 10.2 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 P12 PF12669.2 CDJ65951.1 - 0.1 12.7 0.0 0.42 10.8 0.0 2.0 1 0 0 1 1 1 0 Virus attachment protein p12 family Ribosomal_60s PF00428.14 CDJ65951.1 - 0.98 9.8 36.7 0.09 13.1 2.2 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ65952.1 - 5.9e-06 25.9 68.3 6.7e-05 22.4 21.2 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.2 CDJ65952.1 - 1.6e-05 24.5 1.7 1.6e-05 24.5 1.2 2.6 1 1 1 2 2 1 1 SpoIIIAH-like protein BatD PF13584.1 CDJ65952.1 - 0.00043 19.0 1.6 0.00075 18.2 1.1 1.3 1 0 0 1 1 1 1 Oxygen tolerance DUF912 PF06024.7 CDJ65952.1 - 0.0014 18.6 0.2 0.0014 18.6 0.1 2.8 2 1 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2956 PF11169.3 CDJ65952.1 - 0.0098 15.8 6.2 0.0098 15.8 4.3 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2956) PBP1_TM PF14812.1 CDJ65952.1 - 0.023 14.9 1.9 0.023 14.9 1.3 3.0 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Anoctamin PF04547.7 CDJ65952.1 - 0.12 10.9 0.2 0.21 10.1 0.1 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2207 PF09972.4 CDJ65952.1 - 0.14 10.7 0.1 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MAPEG PF01124.13 CDJ65952.1 - 0.14 11.7 0.1 0.14 11.7 0.1 3.2 4 0 0 4 4 4 0 MAPEG family ODV-E18 PF10717.4 CDJ65952.1 - 0.15 11.5 0.0 0.15 11.5 0.0 2.8 2 0 0 2 2 1 0 Occlusion-derived virus envelope protein ODV-E18 ETRAMP PF09716.5 CDJ65952.1 - 3.2 7.7 25.0 0.078 12.9 5.3 4.3 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Mem_trans PF03547.13 CDJ65952.1 - 3.4 5.8 7.6 8 4.6 5.1 1.9 1 1 0 1 1 1 0 Membrane transport protein RskA PF10099.4 CDJ65952.1 - 3.5 7.3 50.9 0.77 9.4 6.3 4.1 1 1 2 4 4 4 0 Anti-sigma-K factor rskA DUF4341 PF14241.1 CDJ65952.1 - 3.6 7.3 9.1 0.075 12.7 0.6 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4341) SID-1_RNA_chan PF13965.1 CDJ65952.1 - 4.3 5.3 4.3 4 5.4 0.5 1.7 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 DUF4366 PF14283.1 CDJ65952.1 - 7.8 5.8 15.1 2 7.8 0.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) Ribosomal_L18p PF00861.17 CDJ65953.1 - 9.3e-23 80.6 13.1 2.7e-13 50.1 2.9 2.2 1 1 1 2 2 2 2 Ribosomal L18p/L5e family OmpH PF03938.9 CDJ65955.1 - 1.2e-05 25.2 3.3 1.2e-05 25.2 2.3 6.8 5 1 0 5 5 5 1 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDJ65955.1 - 0.00066 18.0 14.4 0.00066 18.0 10.0 8.8 8 1 0 9 9 9 3 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3522 PF12036.3 CDJ65955.1 - 0.0017 18.2 7.1 0.055 13.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3522) SID-1_RNA_chan PF13965.1 CDJ65955.1 - 8.2 4.4 2.0 16 3.4 1.4 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 XRN_N PF03159.13 CDJ65955.1 - 9.4 5.5 5.7 25 4.1 4.0 1.7 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus TP_methylase PF00590.15 CDJ65956.1 - 2.6 7.6 11.8 0.63 9.7 0.5 2.2 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases YEATS PF03366.11 CDJ65957.1 - 1.2e-10 40.9 0.0 1.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 YEATS family DUF4125 PF13526.1 CDJ65957.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) eIF-6 PF01912.13 CDJ65959.1 - 4.6e-77 257.6 0.1 6.2e-77 257.1 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family Suf PF05843.9 CDJ65960.1 - 2.2 7.9 15.4 0.42 10.2 1.9 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PP2C PF00481.16 CDJ65961.1 - 2e-25 89.6 0.0 1.8e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 Protein phosphatase 2C Linocin_M18 PF04454.7 CDJ65961.1 - 0.11 11.4 1.4 0.22 10.3 1.0 1.4 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Abhydrolase_5 PF12695.2 CDJ65962.1 - 9.1e-13 48.1 1.8 9.1e-13 48.1 1.2 4.6 5 2 0 5 5 5 1 Alpha/beta hydrolase family DUF818 PF05677.7 CDJ65962.1 - 0.0053 15.5 0.1 0.11 11.1 0.0 2.3 2 0 0 2 2 2 1 Chlamydia CHLPS protein (DUF818) Spt20 PF12090.3 CDJ65963.1 - 0.043 13.1 1.9 0.046 13.0 1.3 1.2 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.1 CDJ65963.1 - 0.82 8.6 5.7 1.1 8.2 4.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_23 PF13476.1 CDJ65963.1 - 0.93 9.7 11.5 1.2 9.3 8.0 1.2 1 0 0 1 1 1 0 AAA domain CWC25 PF12542.3 CDJ65963.1 - 1.1 9.7 11.5 2 8.9 8.0 1.6 1 1 0 1 1 1 0 Pre-mRNA splicing factor Med3 PF11593.3 CDJ65963.1 - 1.4 8.1 9.9 1.6 7.8 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3881 PF12997.2 CDJ65963.1 - 3 6.7 5.2 1.6 7.6 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) SPX PF03105.14 CDJ65963.1 - 5.1 6.8 11.9 6.2 6.5 8.2 1.1 1 0 0 1 1 1 0 SPX domain BTV_NS2 PF04514.7 CDJ65964.1 - 0.0035 16.2 4.7 0.0042 16.0 3.2 1.1 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 IncA PF04156.9 CDJ65964.1 - 0.0091 15.6 20.5 0.013 15.0 14.2 1.3 1 0 0 1 1 1 1 IncA protein PIH1 PF08190.7 CDJ65964.1 - 0.01 15.2 17.1 0.012 15.1 11.8 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 eIF-3_zeta PF05091.7 CDJ65964.1 - 0.021 13.4 16.8 0.022 13.3 11.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CD20 PF04103.10 CDJ65964.1 - 0.032 14.1 6.1 0.12 12.2 4.2 1.9 1 1 0 1 1 1 0 CD20-like family SAGA-Tad1 PF12767.2 CDJ65964.1 - 0.04 13.5 16.5 0.044 13.4 11.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.9 CDJ65964.1 - 0.059 13.1 19.0 0.071 12.8 13.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spore_coat_CotO PF14153.1 CDJ65964.1 - 0.083 12.3 18.3 0.096 12.1 12.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF2217 PF10265.4 CDJ65964.1 - 0.089 11.5 14.6 0.11 11.2 10.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Ycf1 PF05758.7 CDJ65964.1 - 0.1 10.2 8.5 0.11 10.2 5.9 1.0 1 0 0 1 1 1 0 Ycf1 Plasmodium_Vir PF05795.6 CDJ65964.1 - 0.11 11.6 2.0 0.12 11.5 1.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PMSI1 PF15322.1 CDJ65964.1 - 0.12 11.4 13.6 0.15 11.1 9.4 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative UPF0560 PF10577.4 CDJ65964.1 - 0.15 10.2 18.2 0.16 10.1 12.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Serinc PF03348.10 CDJ65964.1 - 0.15 10.7 10.4 0.18 10.4 7.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Raftlin PF15250.1 CDJ65964.1 - 0.17 10.3 11.9 0.19 10.2 8.3 1.1 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.3 CDJ65964.1 - 0.19 10.2 8.1 0.23 10.0 5.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.8 CDJ65964.1 - 0.21 11.4 29.8 0.24 11.2 20.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4557 PF15101.1 CDJ65964.1 - 0.22 11.3 25.0 0.29 10.9 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 CDJ65964.1 - 0.23 9.1 41.7 0.28 8.8 28.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.5 CDJ65964.1 - 0.24 11.1 9.4 0.32 10.7 6.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.17 CDJ65964.1 - 0.27 10.2 6.1 0.3 10.0 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Folate_carrier PF01770.13 CDJ65964.1 - 0.3 9.5 8.0 0.35 9.3 5.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier PAT1 PF09770.4 CDJ65964.1 - 0.31 9.2 42.4 0.37 8.9 29.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 CDJ65964.1 - 0.51 8.9 10.8 0.57 8.7 7.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.1 CDJ65964.1 - 0.56 8.3 8.1 0.65 8.1 5.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Otopetrin PF03189.8 CDJ65964.1 - 0.6 9.0 5.8 0.63 8.9 4.0 1.1 1 0 0 1 1 1 0 Otopetrin DUF4496 PF14908.1 CDJ65964.1 - 0.66 9.8 9.8 0.86 9.4 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) Spc7_N PF15402.1 CDJ65964.1 - 0.67 7.8 21.2 0.72 7.7 14.7 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Hid1 PF12722.2 CDJ65964.1 - 0.69 7.5 17.5 0.71 7.4 12.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dehalogenase PF13486.1 CDJ65964.1 - 0.69 9.3 7.8 0.86 9.0 5.4 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Med15 PF09606.5 CDJ65964.1 - 0.7 8.0 49.4 0.84 7.7 34.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RIC3 PF15361.1 CDJ65964.1 - 0.79 9.9 17.1 1.3 9.2 11.9 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 CDC45 PF02724.9 CDJ65964.1 - 0.86 7.5 15.4 0.98 7.3 10.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Bud13 PF09736.4 CDJ65964.1 - 0.91 9.7 18.0 1.2 9.3 12.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Cyclin_C PF02984.14 CDJ65964.1 - 0.99 9.3 13.1 1.4 8.8 8.9 1.4 1 1 0 1 1 1 0 Cyclin, C-terminal domain DUF4192 PF13830.1 CDJ65964.1 - 1.1 8.8 12.4 1.3 8.5 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Herpes_glycop PF01528.11 CDJ65964.1 - 1.1 7.8 8.3 1 7.9 5.2 1.3 1 1 0 1 1 1 0 Herpesvirus glycoprotein M Peptidase_S15 PF02129.13 CDJ65964.1 - 1.3 8.3 12.1 1.7 8.0 8.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RR_TM4-6 PF06459.7 CDJ65964.1 - 1.4 8.7 15.2 1.6 8.5 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1675 PF07897.6 CDJ65964.1 - 1.4 8.7 14.1 1.6 8.5 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDHD PF02862.12 CDJ65964.1 - 1.4 8.6 16.2 2 8.1 11.3 1.2 1 0 0 1 1 1 0 DDHD domain Pex16 PF08610.5 CDJ65964.1 - 1.6 7.6 17.4 1.9 7.3 12.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Neur_chan_memb PF02932.11 CDJ65964.1 - 1.6 8.5 11.2 1.9 8.2 7.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 CDJ65964.1 - 1.7 6.8 6.3 2 6.6 4.4 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF966 PF06136.8 CDJ65964.1 - 1.8 7.9 22.2 2 7.7 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FAM60A PF15396.1 CDJ65964.1 - 2 8.1 15.5 3 7.5 10.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CDK5_activator PF03261.10 CDJ65964.1 - 2.1 7.6 18.0 2.4 7.4 12.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein OATP PF03137.15 CDJ65964.1 - 2.1 6.3 8.0 2.5 6.0 5.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DDRGK PF09756.4 CDJ65964.1 - 2.2 7.6 20.5 2.9 7.2 14.2 1.1 1 0 0 1 1 1 0 DDRGK domain Glyco_transf_15 PF01793.11 CDJ65964.1 - 2.2 7.1 13.0 2.7 6.8 9.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Nucleo_P87 PF07267.6 CDJ65964.1 - 2.4 6.7 13.1 2.6 6.6 9.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF913 PF06025.7 CDJ65964.1 - 2.5 6.7 9.4 2.9 6.5 6.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Band_3_cyto PF07565.8 CDJ65964.1 - 2.8 7.3 15.3 3.6 7.0 10.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2058 PF09831.4 CDJ65964.1 - 3 7.6 25.3 3.9 7.3 17.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) FAM176 PF14851.1 CDJ65964.1 - 3.1 7.4 9.2 4.4 6.9 6.4 1.2 1 0 0 1 1 1 0 FAM176 family Hom_end_hint PF05203.11 CDJ65964.1 - 3.6 7.2 10.1 4.5 6.9 7.0 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint AUX_IAA PF02309.11 CDJ65964.1 - 3.7 7.2 14.0 4.5 6.9 9.7 1.2 1 0 0 1 1 1 0 AUX/IAA family Baculo_PP31 PF05311.6 CDJ65964.1 - 3.9 6.6 15.1 5.2 6.2 10.4 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FHIPEP PF00771.15 CDJ65964.1 - 4 5.6 10.5 6.1 5.0 7.3 1.3 1 0 0 1 1 1 0 FHIPEP family AAA_23 PF13476.1 CDJ65964.1 - 4 7.7 11.3 4.8 7.4 7.9 1.1 1 0 0 1 1 1 0 AAA domain Cellulose_synt PF03552.9 CDJ65964.1 - 4 5.5 5.8 4.4 5.4 4.0 1.0 1 0 0 1 1 1 0 Cellulose synthase NARP1 PF12569.3 CDJ65964.1 - 4.3 5.9 16.2 5.1 5.7 11.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FLO_LFY PF01698.11 CDJ65964.1 - 4.4 6.0 16.0 5.2 5.8 11.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4220 PF13968.1 CDJ65964.1 - 4.5 6.2 9.2 5.4 6.0 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF2215 PF10225.4 CDJ65964.1 - 4.6 6.6 9.1 5.1 6.4 6.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) CMV_1a PF12467.3 CDJ65964.1 - 4.6 7.5 16.1 6.7 7.0 11.2 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family GOLD_2 PF13897.1 CDJ65964.1 - 4.9 7.3 6.0 8.6 6.6 4.1 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Paramyxo_ncap PF00973.14 CDJ65964.1 - 5.3 5.6 14.7 5.9 5.4 10.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein 5_nucleotid PF05761.9 CDJ65964.1 - 5.4 5.4 11.9 6.7 5.1 8.2 1.0 1 0 0 1 1 1 0 5' nucleotidase family Pal1 PF08316.6 CDJ65964.1 - 6.3 7.2 9.6 9.1 6.7 6.6 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein CPSF100_C PF13299.1 CDJ65964.1 - 6.9 6.8 14.3 9.4 6.3 9.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_U57 PF05582.7 CDJ65964.1 - 7 5.5 9.6 8.4 5.2 6.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DHHW PF14286.1 CDJ65964.1 - 7.3 5.8 13.0 8.7 5.5 9.0 1.1 1 0 0 1 1 1 0 DHHW protein DUF1501 PF07394.7 CDJ65964.1 - 7.4 5.2 19.2 9.6 4.9 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) AvrE PF11725.3 CDJ65964.1 - 7.7 3.3 21.1 8.5 3.2 14.7 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF3450 PF11932.3 CDJ65964.1 - 7.8 5.6 35.1 10 5.3 24.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lin-8 PF03353.10 CDJ65964.1 - 8.2 5.6 20.3 10 5.2 14.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3605 PF12239.3 CDJ65965.1 - 0.0019 18.0 0.3 0.0047 16.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) S1-P1_nuclease PF02265.11 CDJ65965.1 - 0.0064 16.1 1.9 0.02 14.5 1.3 1.8 1 1 0 1 1 1 1 S1/P1 Nuclease DUF2722 PF10846.3 CDJ65965.1 - 0.0088 15.1 3.1 0.012 14.6 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF2860 PF11059.3 CDJ65965.1 - 0.23 10.4 4.7 0.93 8.4 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2860) Spt20 PF12090.3 CDJ65965.1 - 9.8 5.4 7.6 19 4.5 4.4 1.9 2 1 0 2 2 2 0 Spt20 family TSA PF03249.8 CDJ65965.1 - 9.9 4.5 8.5 12 4.2 5.9 1.1 1 0 0 1 1 1 0 Type specific antigen Corona_nucleoca PF00937.13 CDJ65966.1 - 0.0055 15.6 25.5 0.0055 15.6 17.7 2.1 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein DUF4367 PF14285.1 CDJ65966.1 - 0.04 13.2 0.2 0.04 13.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4367) AAA_23 PF13476.1 CDJ65966.1 - 0.3 11.4 36.8 1.5 9.1 6.5 2.1 2 0 0 2 2 2 0 AAA domain CAF-1_p150 PF11600.3 CDJ65966.1 - 0.89 8.8 62.0 0.084 12.2 19.3 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDJ65967.1 - 0.024 12.8 28.5 0.034 12.3 19.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tail_P2_I PF09684.5 CDJ65967.1 - 0.15 11.5 5.7 0.046 13.2 1.7 1.8 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) AcetylCoA_hydro PF02550.10 CDJ65967.1 - 0.47 10.1 3.1 5.4 6.7 0.1 2.0 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain IER PF05760.7 CDJ65967.1 - 1.3 8.9 19.9 1.7 8.5 13.8 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Peptidase_S64 PF08192.6 CDJ65967.1 - 6.5 4.9 9.0 8.4 4.5 6.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_S15 PF02129.13 CDJ65967.1 - 7 5.9 9.0 1.1 8.6 0.5 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Queuosine_synth PF02547.10 CDJ65968.1 - 0.027 13.2 2.7 1.5 7.4 0.1 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein CDK2AP PF09806.4 CDJ65968.1 - 0.32 11.1 18.4 0.52 10.5 5.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3450 PF11932.3 CDJ65968.1 - 1.5 7.9 10.2 0.26 10.5 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Gram_pos_anchor PF00746.16 CDJ65968.1 - 6.9 6.6 8.5 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Gram positive anchor PAT1 PF09770.4 CDJ65969.1 - 0.001 17.4 68.7 0.0012 17.2 47.6 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDJ65969.1 - 0.18 11.4 29.6 0.25 10.9 20.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Exonuc_VII_L PF02601.10 CDJ65969.1 - 0.2 10.7 20.1 0.27 10.4 13.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Draxin PF15550.1 CDJ65969.1 - 0.64 9.6 17.7 0.81 9.2 12.2 1.1 1 0 0 1 1 1 0 Draxin PLRV_ORF5 PF01690.12 CDJ65969.1 - 0.99 8.4 24.9 1.7 7.7 17.3 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Herpes_UL87 PF03043.9 CDJ65969.1 - 1.6 7.0 9.2 2.1 6.6 6.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family SprA-related PF12118.3 CDJ65969.1 - 2.5 7.3 61.5 5.3 6.2 42.6 1.5 1 0 0 1 1 1 0 SprA-related family V_ATPase_I PF01496.14 CDJ65969.1 - 5 4.8 21.6 6.3 4.5 15.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4045 PF13254.1 CDJ65969.1 - 5.5 6.1 23.0 7.5 5.7 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Spc7 PF08317.6 CDJ65969.1 - 5.9 5.4 32.1 7.8 5.0 22.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PA26 PF04636.8 CDJ65969.1 - 7.8 5.0 20.8 10 4.6 14.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CTP_transf_1 PF01148.15 CDJ65971.1 - 0.014 15.1 17.5 0.02 14.5 0.6 3.7 2 1 1 3 3 3 0 Cytidylyltransferase family Pex14_N PF04695.8 CDJ65971.1 - 2 8.4 12.0 0.062 13.3 0.8 2.9 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 CDJ65971.1 - 7.3 4.6 7.2 9.6 4.2 5.0 1.2 1 0 0 1 1 1 0 Menin PDEase_I PF00233.14 CDJ65972.1 - 1.1e-29 103.9 0.1 2.1e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CDJ65972.1 - 0.14 12.1 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 HD domain hDGE_amylase PF14701.1 CDJ65972.1 - 1.9 7.2 9.9 2.1 7.1 6.3 1.4 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Hid1 PF12722.2 CDJ65972.1 - 8.6 3.8 17.9 13 3.3 12.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IncA PF04156.9 CDJ65973.1 - 0.00012 21.7 18.8 0.00012 21.7 13.0 4.7 3 2 1 4 4 4 1 IncA protein Sporozoite_P67 PF05642.6 CDJ65973.1 - 8.2 4.1 13.5 10 3.8 9.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SID-1_RNA_chan PF13965.1 CDJ65974.1 - 8.2 4.4 7.5 0.62 8.1 0.9 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TPR_2 PF07719.12 CDJ65975.1 - 0.00093 18.9 1.0 0.00093 18.9 0.7 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ65975.1 - 0.0028 17.1 1.9 0.0094 15.5 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ65975.1 - 0.0086 16.6 24.4 0.1 13.2 1.8 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat Tetraspannin PF00335.15 CDJ65975.1 - 0.014 14.7 1.3 0.02 14.1 0.1 1.7 2 0 0 2 2 2 0 Tetraspanin family TPR_11 PF13414.1 CDJ65975.1 - 0.016 14.8 13.0 0.019 14.6 1.3 2.3 2 0 0 2 2 2 0 TPR repeat CH PF00307.26 CDJ65975.1 - 0.11 12.5 0.6 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Calponin homology (CH) domain Usp PF00582.21 CDJ65975.1 - 0.64 10.1 0.0 0.64 10.1 0.0 2.7 2 1 1 3 3 3 0 Universal stress protein family TPR_12 PF13424.1 CDJ65975.1 - 1.1 9.2 12.3 0.28 11.1 0.8 2.9 1 1 3 4 4 4 0 Tetratricopeptide repeat DUF572 PF04502.8 CDJ65976.1 - 0.9 8.6 32.1 1.3 8.2 22.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TPR_19 PF14559.1 CDJ65977.1 - 4.3e-05 23.7 0.4 4.3e-05 23.7 0.3 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat SART-1 PF03343.8 CDJ65977.1 - 0.0077 14.6 1.2 0.008 14.5 0.3 1.5 2 0 0 2 2 2 1 SART-1 family Phage_rep_org_N PF09681.5 CDJ65977.1 - 0.046 13.2 0.2 0.078 12.5 0.2 1.3 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) SoxE PF06525.6 CDJ65977.1 - 1.7 7.9 8.8 3.5 6.8 0.5 2.2 2 0 0 2 2 2 0 Sulfocyanin (SoxE) eIF3g PF12353.3 CDJ65977.1 - 6.8 6.6 7.4 1.6 8.6 1.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Secretin_N_2 PF07655.8 CDJ65977.1 - 8.6 6.8 23.0 1.5 9.2 3.1 3.1 3 0 0 3 3 3 0 Secretin N-terminal domain DUF791 PF05631.9 CDJ65979.1 - 7.7e-06 24.8 0.1 7.7e-06 24.8 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF791) NAD_kinase PF01513.16 CDJ65979.1 - 0.012 14.3 0.2 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 ATP-NAD kinase PPV_E1_N PF00524.13 CDJ65980.1 - 0.013 15.7 0.7 0.035 14.3 0.5 1.7 1 0 0 1 1 1 0 E1 Protein, N terminal domain BAF1_ABF1 PF04684.8 CDJ65981.1 - 0.012 14.4 10.6 0.012 14.4 7.3 3.7 2 1 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDJ65981.1 - 0.45 10.7 33.9 0.44 10.7 5.0 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ribosomal_S19 PF00203.16 CDJ65982.1 - 2.8e-27 94.1 0.0 3.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Siah-Interact_N PF09032.6 CDJ65983.1 - 1.3e-07 31.5 0.7 2.1e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Siah interacting protein, N terminal SGS PF05002.10 CDJ65983.1 - 0.00099 18.8 0.1 0.0029 17.3 0.0 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CDJ65983.1 - 0.028 14.9 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 CS domain LRR_4 PF12799.2 CDJ65985.1 - 4.7e-18 64.3 31.0 8.7e-07 28.4 1.9 3.9 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDJ65985.1 - 7.6e-12 43.5 14.8 0.56 10.4 0.0 6.7 5 1 1 6 6 6 6 Leucine Rich Repeat LRR_8 PF13855.1 CDJ65985.1 - 1.8e-11 43.6 28.5 3.6e-05 23.4 2.8 3.6 2 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 CDJ65985.1 - 5.7e-07 28.9 17.9 2.5 8.4 0.1 6.7 3 2 3 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 CDJ65985.1 - 9.6e-07 28.0 17.4 0.57 10.6 0.1 6.6 6 1 0 6 6 6 3 Leucine rich repeat LRR_9 PF14580.1 CDJ65985.1 - 2e-05 24.2 1.2 0.004 16.7 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat Surp PF01805.15 CDJ65986.1 - 1.9e-07 30.6 0.3 6.2e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Surp module CDC45 PF02724.9 CDJ65986.1 - 5.3 4.9 9.2 11 3.9 6.4 1.5 1 0 0 1 1 1 0 CDC45-like protein SHS2_Rpb7-N PF03876.12 CDJ65987.1 - 1.1e-12 47.8 0.1 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 polyprenyl_synt PF00348.12 CDJ65988.1 - 9.7e-33 113.1 0.0 2.2e-30 105.3 0.0 2.8 2 1 0 2 2 2 2 Polyprenyl synthetase DUF3780 PF12635.2 CDJ65988.1 - 0.022 14.2 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) Viral_DNA_bi PF02236.12 CDJ65988.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain adh_short PF00106.20 CDJ65990.1 - 7.2e-19 68.3 0.0 2.6e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDJ65990.1 - 2.6e-09 36.9 0.1 9.2e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CDJ65990.1 - 0.00089 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase B-block_TFIIIC PF04182.7 CDJ65991.1 - 1.3e-08 34.5 0.0 5.3e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 CDJ65991.1 - 0.00097 18.7 0.4 1 9.0 0.0 3.4 3 0 0 3 3 3 2 MarR family DUF2005 PF09407.5 CDJ65992.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2005) TAF1_subA PF14929.1 CDJ65993.1 - 0.031 12.7 0.0 0.061 11.7 0.0 1.4 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A G3P_antiterm PF04309.7 CDJ65994.1 - 0.11 11.4 0.0 0.57 9.2 0.0 2.0 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DUF4131 PF13567.1 CDJ65994.1 - 6.8 6.0 29.7 1.9 7.8 5.9 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4131) HSP70 PF00012.15 CDJ65995.1 - 5.3e-264 876.7 7.7 6.1e-264 876.5 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CDJ65995.1 - 2.7e-15 55.8 1.9 4.9e-13 48.3 0.2 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CDJ65995.1 - 0.0053 16.5 4.1 0.83 9.5 0.0 4.0 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 CDJ65995.1 - 0.0098 15.5 0.4 0.025 14.2 0.1 1.9 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Sec2p PF06428.6 CDJ65995.1 - 0.12 12.2 9.0 8 6.3 6.2 2.5 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p ATP-synt_B PF00430.13 CDJ65995.1 - 2 8.1 10.8 5 6.9 7.5 1.7 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) SR-25 PF10500.4 CDJ65996.1 - 0.0001 21.8 31.9 0.00016 21.2 22.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med19 PF10278.4 CDJ65996.1 - 0.05 13.2 17.9 0.087 12.4 12.4 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Zip PF02535.17 CDJ65996.1 - 0.065 12.2 2.8 0.093 11.7 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2413 PF10310.4 CDJ65996.1 - 0.39 9.4 11.7 0.53 9.0 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Neur_chan_memb PF02932.11 CDJ65996.1 - 0.51 10.1 5.4 0.69 9.7 3.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF566 PF04484.7 CDJ65996.1 - 0.72 9.3 14.9 0.97 8.8 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MIP-T3 PF10243.4 CDJ65996.1 - 0.75 8.1 16.9 0.97 7.8 11.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3827 PF12877.2 CDJ65996.1 - 0.8 7.7 13.4 1 7.3 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) zf-RanBP PF00641.13 CDJ65996.1 - 1.4 8.1 5.8 3.1 6.9 4.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF4614 PF15391.1 CDJ65996.1 - 1.7 8.4 14.7 2.4 7.9 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) TFIIF_alpha PF05793.7 CDJ65996.1 - 1.8 6.8 22.0 2.2 6.5 15.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleo_P87 PF07267.6 CDJ65996.1 - 2 6.9 6.0 2.5 6.6 4.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FancD2 PF14631.1 CDJ65996.1 - 2.5 5.1 8.3 3.2 4.7 5.7 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF1510 PF07423.6 CDJ65996.1 - 2.8 7.2 12.5 3.8 6.8 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TATR PF03430.8 CDJ65996.1 - 3 6.3 7.0 4.3 5.8 4.8 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Hid1 PF12722.2 CDJ65996.1 - 3.3 5.2 6.1 4 4.9 4.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 CDJ65996.1 - 7.1 4.5 13.1 9.5 4.1 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CDJ65997.1 - 0.00082 17.8 33.2 0.00082 17.8 23.0 4.1 3 1 1 4 4 4 3 Transmembrane protein Peptidase_M56 PF05569.6 CDJ65999.1 - 0.26 10.2 0.1 0.45 9.4 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 PIG-X PF08320.7 CDJ66000.1 - 1e-07 31.4 0.0 0.0086 15.3 0.0 2.6 2 1 1 3 3 3 2 PIG-X / PBN1 RNase_Zc3h12a PF11977.3 CDJ66002.1 - 1.2e-26 93.4 0.0 4.3e-26 91.6 0.0 2.0 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain N6_N4_Mtase PF01555.13 CDJ66002.1 - 0.0069 15.8 0.1 0.0069 15.8 0.1 1.8 2 0 0 2 2 2 1 DNA methylase DCX PF03607.12 CDJ66003.1 - 3.1e-09 36.2 0.0 1.1e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Doublecortin p25-alpha PF05517.7 CDJ66003.1 - 3.5e-06 27.3 0.1 9.4e-06 25.9 0.1 1.6 2 0 0 2 2 2 1 p25-alpha Citrate_synt PF00285.16 CDJ66004.1 - 3.5e-90 302.3 0.0 8.9e-89 297.6 0.0 2.2 1 1 0 1 1 1 1 Citrate synthase RNA_polI_A14 PF08203.6 CDJ66004.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF4316 PF14195.1 CDJ66006.1 - 7.3 6.7 8.1 0.36 10.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) DUF3883 PF13020.1 CDJ66007.1 - 2.3e-18 65.7 0.0 4.5e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Cupin_8 PF13621.1 CDJ66008.1 - 7.3e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain zf-HC2 PF13490.1 CDJ66008.1 - 0.027 14.4 1.1 0.036 14.0 0.1 1.8 2 0 0 2 2 2 0 Putative zinc-finger Cupin_8 PF13621.1 CDJ66009.1 - 1.1e-30 106.9 0.0 2.2e-30 106.0 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CDJ66009.1 - 0.00011 21.5 0.2 0.046 12.9 0.0 3.1 3 0 0 3 3 3 2 Cupin superfamily protein Fmp27_WPPW PF10359.4 CDJ66009.1 - 0.13 10.6 0.4 0.21 9.9 0.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4398 PF14346.1 CDJ66009.1 - 3.5 7.7 10.2 0.13 12.2 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Rieske PF00355.21 CDJ66010.1 - 4.9e-15 54.8 0.1 1e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 CDJ66010.1 - 0.00022 21.3 0.0 0.00048 20.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region EXS PF03124.9 CDJ66016.1 - 4.4e-66 223.2 6.0 6.1e-66 222.8 4.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CDJ66016.1 - 8.9e-27 94.5 0.1 1.3e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 SPX domain DrsE PF02635.10 CDJ66017.1 - 0.35 10.9 7.3 0.4 10.7 5.1 1.1 1 0 0 1 1 1 0 DsrE/DsrF-like family Helicase_RecD PF05127.9 CDJ66017.1 - 1.2 8.7 6.1 1.6 8.3 4.2 1.1 1 0 0 1 1 1 0 Helicase Fringe PF02434.11 CDJ66018.1 - 2e-17 63.2 0.0 4.3e-07 29.3 0.0 3.4 3 0 0 3 3 3 3 Fringe-like Med15 PF09606.5 CDJ66019.1 - 5.7e-05 21.5 73.6 5.7e-05 21.5 51.0 2.9 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ66020.1 - 0.15 11.3 12.2 0.25 10.6 0.2 3.9 4 0 0 4 4 4 0 Spt20 family FimP PF09766.4 CDJ66020.1 - 1.3 8.0 23.6 1.5 7.8 2.3 3.7 4 0 0 4 4 4 0 Fms-interacting protein AAA_23 PF13476.1 CDJ66021.1 - 0.23 11.7 5.4 0.31 11.3 3.7 1.2 1 0 0 1 1 1 0 AAA domain PAS_4 PF08448.5 CDJ66021.1 - 0.92 9.5 6.5 2.9 7.9 0.7 2.3 1 1 1 2 2 2 0 PAS fold Med15 PF09606.5 CDJ66021.1 - 3.6 5.6 33.6 5.2 5.1 23.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4140 PF13600.1 CDJ66021.1 - 5.3 7.5 9.6 1.8 9.0 1.5 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Adaptin_binding PF10199.4 CDJ66023.1 - 1.4e-09 38.3 7.1 1.4e-09 38.3 4.9 2.7 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 FimP PF09766.4 CDJ66023.1 - 5.7e-05 22.3 11.5 5.7e-05 22.3 8.0 2.7 3 0 0 3 3 3 1 Fms-interacting protein SR-25 PF10500.4 CDJ66023.1 - 0.00026 20.5 14.5 0.00026 20.5 10.1 5.2 3 1 2 5 5 5 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.1 CDJ66023.1 - 0.35 11.1 12.2 0.11 12.7 6.1 1.9 2 0 0 2 2 2 0 AAA domain DUF605 PF04652.11 CDJ66023.1 - 0.58 9.4 39.4 0.61 9.4 13.4 2.3 2 0 0 2 2 2 0 Vta1 like Pex14_N PF04695.8 CDJ66023.1 - 2.5 8.1 41.4 0.17 11.9 9.5 3.8 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIIAH PF12685.2 CDJ66023.1 - 3 7.3 30.4 73 2.7 0.3 3.4 2 1 0 2 2 2 0 SpoIIIAH-like protein Apt1 PF10351.4 CDJ66023.1 - 5.1 5.8 23.8 2.2 7.0 7.1 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Fmp27 PF10344.4 CDJ66026.1 - 0.84 7.2 11.0 1.4 6.4 7.6 1.3 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF4613 PF15390.1 CDJ66026.1 - 2.2 6.3 9.1 3.2 5.8 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) U3_snoRNA_assoc PF08297.6 CDJ66026.1 - 7.2 6.9 13.7 0.23 11.7 1.8 3.0 2 1 1 3 3 3 0 U3 snoRNA associated DUF605 PF04652.11 CDJ66027.1 - 0.28 10.5 19.1 0.3 10.4 13.3 1.1 1 0 0 1 1 1 0 Vta1 like CAML PF14963.1 CDJ66027.1 - 0.86 8.9 11.4 1.4 8.2 7.9 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Macoilin PF09726.4 CDJ66027.1 - 1.7 6.7 33.9 2 6.6 23.5 1.1 1 0 0 1 1 1 0 Transmembrane protein SprA-related PF12118.3 CDJ66027.1 - 1.8 7.8 23.1 2 7.6 16.0 1.1 1 0 0 1 1 1 0 SprA-related family Raftlin PF15250.1 CDJ66027.1 - 2.7 6.4 7.7 3.2 6.1 5.4 1.1 1 0 0 1 1 1 0 Raftlin CytochromB561_N PF09786.4 CDJ66027.1 - 4.9 5.4 29.5 5.7 5.2 20.4 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Tmemb_cc2 PF10267.4 CDJ66027.1 - 9.2 4.7 18.8 13 4.2 13.1 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Spore_III_AB PF09548.5 CDJ66028.1 - 0.019 14.7 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Zip PF02535.17 CDJ66029.1 - 0.51 9.3 4.3 0.78 8.6 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2217 PF10265.4 CDJ66029.1 - 2 7.0 13.9 3 6.4 3.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Hid1 PF12722.2 CDJ66029.1 - 2.9 5.4 7.2 4.3 4.8 5.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.7 CDJ66029.1 - 3.1 6.4 6.7 5.1 5.7 4.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ycf1 PF05758.7 CDJ66029.1 - 5.8 4.4 10.5 8.3 3.9 7.3 1.1 1 0 0 1 1 1 0 Ycf1 MMR1 PF08505.5 CDJ66029.1 - 6.8 6.6 20.1 1.1 9.3 9.7 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SID-1_RNA_chan PF13965.1 CDJ66029.1 - 7.8 4.5 5.9 11 4.0 4.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FLO_LFY PF01698.11 CDJ66029.1 - 8.7 5.0 13.6 17 4.0 9.4 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein TPR_1 PF00515.23 CDJ66030.1 - 0.0034 16.9 0.3 0.22 11.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3446 PF11928.3 CDJ66030.1 - 0.018 15.2 4.1 0.018 15.2 2.8 4.4 3 2 0 3 3 1 0 Domain of unknown function (DUF3446) Chorion_S16 PF05836.7 CDJ66030.1 - 0.024 14.5 0.4 0.024 14.5 0.3 4.7 3 1 2 5 5 1 0 Chorion protein S16 TPR_2 PF07719.12 CDJ66030.1 - 0.047 13.6 0.6 0.047 13.6 0.4 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Ycf1 PF05758.7 CDJ66030.1 - 0.057 11.1 10.1 0.063 11.0 7.0 1.1 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 CDJ66030.1 - 0.22 10.8 31.3 0.23 10.7 12.0 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dehydrin PF00257.14 CDJ66030.1 - 0.26 11.5 24.5 2 8.7 14.0 2.4 2 0 0 2 2 2 0 Dehydrin SR-25 PF10500.4 CDJ66030.1 - 0.36 10.2 39.8 0.56 9.6 7.4 2.6 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein MDM1 PF15501.1 CDJ66030.1 - 0.43 9.4 32.7 0.79 8.5 16.1 2.2 2 0 0 2 2 2 0 Nuclear protein MDM1 DDRGK PF09756.4 CDJ66030.1 - 0.82 9.0 24.3 1.5 8.2 16.9 1.4 1 0 0 1 1 1 0 DDRGK domain DNA_pol_viral_N PF00242.12 CDJ66030.1 - 2.8 6.8 17.6 0.66 8.9 6.4 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Pox_Ag35 PF03286.9 CDJ66030.1 - 4.2 6.8 21.8 0.31 10.5 9.2 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein eIF-3_zeta PF05091.7 CDJ66030.1 - 4.4 5.8 19.1 1.8 7.0 11.7 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BTV_NS2 PF04514.7 CDJ66030.1 - 5.6 5.7 17.0 11 4.8 11.8 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 CDJ66030.1 - 8.1 6.1 18.9 4.1 7.0 8.2 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Paramyxo_ncap PF00973.14 CDJ66030.1 - 10 4.7 14.4 20 3.7 10.0 1.4 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ATP_bind_1 PF03029.12 CDJ66033.1 - 5.4e-30 104.6 0.0 1.3e-26 93.6 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CDJ66033.1 - 0.014 14.8 0.0 0.08 12.3 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NUDIX_2 PF13869.1 CDJ66033.1 - 0.045 13.0 0.0 3.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Nucleotide hydrolase SR-25 PF10500.4 CDJ66034.1 - 4.7e-05 22.9 40.9 4.7e-05 22.9 28.4 8.1 7 2 3 10 10 10 2 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDJ66034.1 - 0.0047 17.2 6.8 0.0047 17.2 4.7 20.1 13 4 6 19 19 19 5 60s Acidic ribosomal protein APC_CDC26 PF10471.4 CDJ66034.1 - 0.0053 17.4 2.0 0.0053 17.4 1.4 9.6 7 3 2 9 9 9 2 Anaphase-promoting complex APC subunit 1 AP2 PF00847.15 CDJ66035.1 - 1.1e-06 28.6 1.6 1.1e-06 28.6 1.1 3.4 3 0 0 3 3 2 1 AP2 domain ACDC PF14733.1 CDJ66035.1 - 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal TALPID3 PF15324.1 CDJ66035.1 - 0.0053 14.1 0.5 0.0053 14.1 0.4 2.1 2 0 0 2 2 2 1 Hedgehog signalling target TRAP_alpha PF03896.11 CDJ66035.1 - 0.023 13.7 4.1 0.031 13.2 2.4 1.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Kei1 PF08552.6 CDJ66035.1 - 0.09 12.4 3.5 0.14 11.8 2.5 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LpxB PF02684.10 CDJ66035.1 - 0.12 10.9 4.2 13 4.2 3.1 2.6 2 1 0 2 2 2 0 Lipid-A-disaccharide synthetase Apc15p PF05841.6 CDJ66035.1 - 0.16 12.7 8.8 0.34 11.6 5.3 2.1 2 0 0 2 2 2 0 Apc15p protein DUF1822 PF08852.6 CDJ66035.1 - 0.17 10.6 16.1 0.4 9.4 11.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) SHR3_chaperone PF08229.6 CDJ66035.1 - 0.17 10.7 7.7 0.29 10.0 5.3 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 EPL1 PF10513.4 CDJ66035.1 - 1.9 8.7 7.4 1.2 9.3 3.6 1.7 2 0 0 2 2 2 0 Enhancer of polycomb-like Band_3_cyto PF07565.8 CDJ66035.1 - 2.9 7.3 9.6 5.4 6.4 6.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Thioredoxin_4 PF13462.1 CDJ66035.1 - 3.7 7.5 18.5 11 6.0 0.5 2.5 2 1 0 2 2 2 0 Thioredoxin VIT1 PF01988.14 CDJ66035.1 - 4.2 6.7 11.6 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 VIT family DUF2360 PF10152.4 CDJ66035.1 - 5.2 7.3 23.2 0.11 12.7 6.7 2.9 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4557 PF15101.1 CDJ66035.1 - 8.6 6.1 12.8 20 4.9 8.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MDMPI_N PF11716.3 CDJ66035.1 - 9.9 6.5 29.6 0.31 11.4 11.4 2.9 3 0 0 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF755 PF05501.6 CDJ66036.1 - 0.0001 22.3 0.3 0.0001 22.3 0.2 7.2 7 1 0 7 7 7 1 Domain of unknown function (DUF755) ThiF PF00899.16 CDJ66039.1 - 4.1e-23 81.7 2.2 7.6e-14 51.6 0.0 4.3 3 1 1 4 4 4 3 ThiF family SR-25 PF10500.4 CDJ66039.1 - 3.5e-07 29.9 8.3 3.5e-07 29.9 5.8 2.7 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 CDJ66039.1 - 0.00088 18.2 9.5 0.00088 18.2 6.6 4.6 3 1 1 4 4 2 1 BAF1 / ABF1 chromatin reorganising factor EPL1 PF10513.4 CDJ66039.1 - 0.011 16.0 5.0 0.74 10.0 0.2 3.3 3 0 0 3 3 3 0 Enhancer of polycomb-like Suf PF05843.9 CDJ66039.1 - 0.011 15.4 8.7 0.71 9.5 0.8 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDJ66039.1 - 0.029 14.3 23.4 0.089 12.8 4.9 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Adaptin_binding PF10199.4 CDJ66039.1 - 0.048 13.9 10.2 0.27 11.4 3.9 2.6 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Apt1 PF10351.4 CDJ66039.1 - 0.21 10.4 5.1 0.4 9.4 3.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF913 PF06025.7 CDJ66039.1 - 0.61 8.7 4.1 0.88 8.2 0.4 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Bul1_C PF04426.7 CDJ66039.1 - 0.65 9.1 4.0 1.5 7.9 2.8 1.5 1 0 0 1 1 1 0 Bul1 C terminus FAM60A PF15396.1 CDJ66039.1 - 1.3 8.7 11.5 0.069 12.8 2.5 2.5 3 0 0 3 3 3 0 Protein Family FAM60A DAGK_cat PF00781.19 CDJ66040.1 - 8e-13 47.9 0.8 6.2e-09 35.3 0.0 3.5 1 1 2 3 3 3 3 Diacylglycerol kinase catalytic domain SMN PF06003.7 CDJ66040.1 - 0.024 13.7 1.1 0.037 13.1 0.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SLD3 PF08639.5 CDJ66041.1 - 0.013 14.1 6.9 0.014 14.1 4.8 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF605 PF04652.11 CDJ66041.1 - 0.077 12.3 14.0 0.092 12.1 9.7 1.1 1 0 0 1 1 1 0 Vta1 like Phage_sheath_1 PF04984.9 CDJ66041.1 - 0.72 8.2 6.6 0.82 8.0 4.6 1.1 1 0 0 1 1 1 0 Phage tail sheath protein PAP1 PF08601.5 CDJ66041.1 - 0.92 9.1 20.0 1.2 8.8 13.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Secretin_N_2 PF07655.8 CDJ66041.1 - 1.8 9.0 26.9 0.77 10.1 2.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Apt1 PF10351.4 CDJ66041.1 - 2.4 6.9 13.5 3.4 6.4 9.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.4 CDJ66041.1 - 4.9 5.3 20.7 6.9 4.8 14.4 1.2 1 0 0 1 1 1 0 Transmembrane protein AAA_23 PF13476.1 CDJ66042.1 - 0.0033 17.7 12.5 0.0051 17.1 8.7 1.2 1 0 0 1 1 1 1 AAA domain V_ATPase_I PF01496.14 CDJ66042.1 - 5.5 4.7 5.4 7.6 4.2 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DJ-1_PfpI PF01965.19 CDJ66045.1 - 0.00017 21.0 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Phage-A118_gp45 PF10653.4 CDJ66045.1 - 0.0015 18.3 0.1 1.3 8.9 0.0 2.3 1 1 1 2 2 2 2 Protein gp45 of Bacteriophage A118 IN_DBD_C PF00552.16 CDJ66045.1 - 0.08 12.3 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Integrase DNA binding domain SprA-related PF12118.3 CDJ66046.1 - 0.0067 15.7 43.6 0.0076 15.6 30.2 1.0 1 0 0 1 1 1 1 SprA-related family RskA PF10099.4 CDJ66046.1 - 0.056 13.1 17.5 0.073 12.8 12.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA KfrA_N PF11740.3 CDJ66046.1 - 1.4 9.3 29.6 1.9 8.9 20.5 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Macoilin PF09726.4 CDJ66046.1 - 4.6 5.4 38.3 5.5 5.1 26.5 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CDJ66046.1 - 9.7 5.9 35.0 12 5.6 24.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RskA PF10099.4 CDJ66047.1 - 0.051 13.2 3.1 0.056 13.1 2.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA HdeA PF06411.6 CDJ66047.1 - 1.1 9.2 6.5 2.5 8.1 4.5 1.6 1 0 0 1 1 1 0 HdeA/HdeB family TSA PF03249.8 CDJ66047.1 - 4.2 5.8 18.4 4.8 5.6 12.8 1.0 1 0 0 1 1 1 0 Type specific antigen DUF2217 PF10265.4 CDJ66047.1 - 5.2 5.7 11.9 5.8 5.5 8.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3761 PF12587.3 CDJ66047.1 - 8.8 6.5 13.8 19 5.4 9.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3761) DUF1645 PF07816.6 CDJ66048.1 - 0.018 15.4 20.5 0.024 15.0 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) EB1_binding PF05937.6 CDJ66048.1 - 0.069 13.5 11.1 0.12 12.7 7.7 1.4 1 1 0 1 1 1 0 EB-1 Binding Domain SR-25 PF10500.4 CDJ66048.1 - 0.57 9.6 28.9 1.4 8.3 20.0 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF508 PF04370.7 CDJ66048.1 - 0.63 9.6 6.0 1.2 8.7 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF755 PF05501.6 CDJ66048.1 - 0.84 9.6 19.7 1.8 8.6 13.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TFIIF_alpha PF05793.7 CDJ66048.1 - 3.5 5.8 11.4 4 5.7 7.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ndc1_Nup PF09531.5 CDJ66048.1 - 4.5 5.5 7.3 4.9 5.4 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup COPI_assoc PF08507.5 CDJ66050.1 - 0.00044 19.9 1.9 0.00071 19.2 1.3 1.3 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 CDJ66050.1 - 2 8.4 6.8 0.45 10.4 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein CG6151-P Apq12 PF12716.2 CDJ66050.1 - 2.8 7.6 10.2 0.13 11.9 0.5 2.7 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis RAP PF08373.5 CDJ66051.1 - 0.00077 19.1 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 RAP domain RP-C_C PF11800.3 CDJ66051.1 - 0.0063 16.2 4.6 0.011 15.4 3.2 1.5 1 0 0 1 1 1 1 Replication protein C C-terminal region AUX_IAA PF02309.11 CDJ66051.1 - 0.044 13.5 1.6 0.06 13.0 1.1 1.3 1 0 0 1 1 1 0 AUX/IAA family BRF1 PF07741.8 CDJ66051.1 - 0.059 13.6 4.8 0.14 12.4 3.3 1.7 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FAM176 PF14851.1 CDJ66051.1 - 0.064 12.9 0.5 0.13 11.9 0.4 1.5 1 0 0 1 1 1 0 FAM176 family BAF1_ABF1 PF04684.8 CDJ66051.1 - 0.075 11.8 23.1 0.011 14.6 13.0 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF4557 PF15101.1 CDJ66051.1 - 0.086 12.6 12.8 0.17 11.7 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 CDJ66051.1 - 0.14 11.8 5.8 0.17 11.5 4.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4080 PF13311.1 CDJ66051.1 - 0.16 12.0 3.6 0.26 11.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Neur_chan_memb PF02932.11 CDJ66051.1 - 0.17 11.7 0.5 0.18 11.6 0.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 CDJ66051.1 - 0.4 8.8 29.3 0.55 8.3 20.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1764 PF08576.5 CDJ66051.1 - 0.49 11.1 8.4 0.96 10.2 5.8 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pex14_N PF04695.8 CDJ66051.1 - 9.2 6.3 17.6 12 5.9 11.5 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.14 CDJ66053.1 - 0.0076 16.6 11.4 0.0076 16.6 7.9 3.9 2 1 0 2 2 2 1 60s Acidic ribosomal protein PQ-loop PF04193.9 CDJ66053.1 - 0.031 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 PQ loop repeat DUF3121 PF11319.3 CDJ66053.1 - 3.6 7.0 5.6 4 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) S1 PF00575.18 CDJ66054.1 - 2.7e-11 43.3 0.2 3.4e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 S1 RNA binding domain EcKinase PF02958.15 CDJ66054.1 - 0.0041 16.2 0.1 0.0049 16.0 0.1 1.0 1 0 0 1 1 1 1 Ecdysteroid kinase EXOSC1 PF10447.4 CDJ66054.1 - 0.061 13.2 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 RNA_pol_Rpb1_2 PF00623.15 CDJ66056.1 - 1.2e-61 207.5 0.0 1.6e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 CDJ66056.1 - 3.9e-36 124.9 0.0 5.5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 CDJ66056.1 - 1.3e-18 67.1 0.0 2.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 ASFV_J13L PF05568.6 CDJ66056.1 - 0.41 10.1 1.6 0.73 9.3 1.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Ribosomal_60s PF00428.14 CDJ66056.1 - 0.51 10.7 14.2 0.048 14.0 6.6 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3138 PF11336.3 CDJ66056.1 - 0.71 7.9 2.1 1.1 7.3 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Fasciclin PF02469.17 CDJ66057.1 - 3.3e-11 43.2 0.0 6.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain SR-25 PF10500.4 CDJ66057.1 - 0.00041 19.8 34.5 0.0043 16.5 8.9 3.1 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 CDJ66057.1 - 0.0088 14.9 7.4 0.017 13.9 5.1 1.5 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Dehydrin PF00257.14 CDJ66057.1 - 0.029 14.7 15.3 0.31 11.3 5.5 2.8 2 1 0 2 2 2 0 Dehydrin Serglycin PF04360.7 CDJ66057.1 - 0.065 12.9 4.7 1.3 8.7 0.7 2.4 2 0 0 2 2 2 0 Serglycin DUF3446 PF11928.3 CDJ66057.1 - 0.16 12.1 21.2 0.48 10.6 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF1266 PF06889.6 CDJ66057.1 - 0.47 10.2 4.6 1.1 9.0 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) SR-25 PF10500.4 CDJ66058.1 - 2.8e-07 30.2 22.5 4.5e-07 29.5 15.6 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein NAM-associated PF14303.1 CDJ66058.1 - 0.00038 20.8 8.6 0.00048 20.4 6.0 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF4207 PF13904.1 CDJ66058.1 - 0.00081 18.8 17.8 0.001 18.4 12.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) Cwf_Cwc_15 PF04889.7 CDJ66058.1 - 0.00095 18.9 4.6 0.0013 18.5 3.2 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Med15 PF09606.5 CDJ66058.1 - 0.0012 17.1 21.1 0.0014 16.9 14.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ66058.1 - 0.0032 17.8 12.2 0.0049 17.2 8.4 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein SprA-related PF12118.3 CDJ66058.1 - 0.0033 16.8 22.6 0.0049 16.2 15.7 1.2 1 0 0 1 1 1 1 SprA-related family CAF-1_p150 PF11600.3 CDJ66058.1 - 0.0054 16.1 15.3 0.0074 15.6 10.6 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3801 PF12687.2 CDJ66058.1 - 0.024 14.2 9.6 0.029 13.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) WTX PF09422.5 CDJ66058.1 - 0.053 12.4 13.3 0.062 12.2 9.2 1.0 1 0 0 1 1 1 0 WTX protein Suf PF05843.9 CDJ66058.1 - 0.13 11.9 9.0 0.15 11.7 6.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ66058.1 - 0.13 12.1 14.5 0.15 11.9 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OMP_b-brl PF13505.1 CDJ66058.1 - 0.14 12.0 5.1 0.18 11.7 3.6 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain CDC45 PF02724.9 CDJ66058.1 - 0.16 9.9 10.5 0.19 9.6 7.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RAB3GAP2_N PF14655.1 CDJ66058.1 - 0.17 10.8 9.8 0.19 10.6 6.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DDHD PF02862.12 CDJ66058.1 - 0.17 11.6 11.3 0.2 11.4 7.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF3450 PF11932.3 CDJ66058.1 - 0.17 11.1 17.6 0.23 10.7 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Suc_Fer-like PF06999.7 CDJ66058.1 - 0.2 11.6 5.9 0.4 10.6 4.1 1.4 1 1 0 1 1 1 0 Sucrase/ferredoxin-like Nop53 PF07767.6 CDJ66058.1 - 0.22 10.4 11.3 0.27 10.1 7.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MSP1_C PF07462.6 CDJ66058.1 - 0.5 8.6 8.8 0.55 8.5 6.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Macoilin PF09726.4 CDJ66058.1 - 0.8 7.9 18.0 1.2 7.2 12.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Prp18 PF02840.10 CDJ66058.1 - 0.98 9.2 5.6 1.7 8.4 3.9 1.3 1 0 0 1 1 1 0 Prp18 domain SOBP PF15279.1 CDJ66058.1 - 0.99 9.7 8.4 1.2 9.4 5.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DOR PF14839.1 CDJ66058.1 - 1 9.0 16.9 1.6 8.4 11.7 1.3 1 0 0 1 1 1 0 DOR family THRAP3_BCLAF1 PF15440.1 CDJ66058.1 - 1.1 7.8 19.2 1.4 7.4 13.3 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Presenilin PF01080.12 CDJ66058.1 - 1.2 7.8 7.9 1.5 7.5 5.5 1.1 1 0 0 1 1 1 0 Presenilin DUF3337 PF11816.3 CDJ66058.1 - 1.8 7.8 9.4 2.2 7.6 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Bul1_C PF04426.7 CDJ66058.1 - 1.9 7.5 7.8 2.6 7.1 5.4 1.1 1 0 0 1 1 1 0 Bul1 C terminus Rtf2 PF04641.7 CDJ66058.1 - 4.9 6.2 11.9 6.3 5.9 8.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Apt1 PF10351.4 CDJ66058.1 - 5 5.8 13.5 5.8 5.6 9.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.7 CDJ66058.1 - 5.9 5.4 13.4 7 5.1 9.3 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2146 PF10220.4 CDJ66058.1 - 7.6 4.3 12.6 8.9 4.1 8.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Ribosomal_60s PF00428.14 CDJ66060.1 - 0.0042 17.4 0.8 0.012 16.0 0.5 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Herpes_capsid PF06112.6 CDJ66060.1 - 0.79 9.7 9.3 0.38 10.7 4.6 1.7 1 1 1 2 2 2 0 Gammaherpesvirus capsid protein PHD PF00628.24 CDJ66062.1 - 1.8e-07 30.7 4.2 6.3e-07 28.9 2.9 1.9 1 0 0 1 1 1 1 PHD-finger Macoilin PF09726.4 CDJ66062.1 - 8.6e-05 21.0 10.8 8.6e-05 21.0 7.5 3.8 4 0 0 4 4 4 1 Transmembrane protein DUF755 PF05501.6 CDJ66062.1 - 0.011 15.7 17.5 0.011 15.7 12.2 5.2 5 0 0 5 5 5 0 Domain of unknown function (DUF755) zf-DHHC PF01529.15 CDJ66062.1 - 0.65 9.3 0.0 0.65 9.3 0.0 3.5 4 1 0 4 4 4 0 DHHC palmitoyltransferase PAT1 PF09770.4 CDJ66064.1 - 4.5 5.3 20.4 5.8 5.0 14.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDJ66066.1 - 0.0052 16.1 21.9 0.0052 16.1 15.2 3.9 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dehydrin PF00257.14 CDJ66066.1 - 0.079 13.2 0.2 0.079 13.2 0.1 3.6 2 1 0 3 3 3 0 Dehydrin BAF1_ABF1 PF04684.8 CDJ66067.1 - 0.00074 18.4 33.0 0.0012 17.8 22.9 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Apc15p PF05841.6 CDJ66067.1 - 0.0011 19.6 12.4 0.0015 19.2 8.6 1.2 1 0 0 1 1 1 1 Apc15p protein VIT1 PF01988.14 CDJ66067.1 - 0.0065 15.9 3.4 0.0081 15.6 2.4 1.1 1 0 0 1 1 1 1 VIT family PAT1 PF09770.4 CDJ66067.1 - 0.023 12.9 25.7 0.026 12.8 17.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ66067.1 - 0.029 12.5 47.6 0.034 12.3 33.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDJ66067.1 - 0.061 12.0 45.9 0.072 11.8 31.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF966 PF06136.8 CDJ66067.1 - 0.062 12.7 8.4 0.065 12.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Plasmodium_Vir PF05795.6 CDJ66067.1 - 0.081 12.1 1.3 0.088 11.9 0.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Band_3_cyto PF07565.8 CDJ66067.1 - 0.2 11.1 10.5 0.23 10.9 7.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gly_rich PF12810.2 CDJ66067.1 - 0.24 10.9 8.2 0.31 10.5 5.7 1.2 1 0 0 1 1 1 0 Glycine rich protein Gag_spuma PF03276.9 CDJ66067.1 - 0.3 9.3 23.2 0.3 9.3 16.1 1.2 1 0 0 1 1 1 0 Spumavirus gag protein CDK5_activator PF03261.10 CDJ66067.1 - 0.34 10.2 10.9 0.41 9.9 7.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein HGTP_anticodon2 PF12745.2 CDJ66067.1 - 0.45 9.6 9.3 0.54 9.3 6.4 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4175 PF13779.1 CDJ66067.1 - 0.57 7.8 47.4 0.66 7.5 32.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SAPS PF04499.10 CDJ66067.1 - 0.64 8.5 8.7 0.71 8.4 6.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Totivirus_coat PF05518.6 CDJ66067.1 - 1.1 7.0 19.5 1.3 6.7 13.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein Ycf1 PF05758.7 CDJ66067.1 - 1.1 6.8 9.4 1.1 6.8 6.5 1.0 1 0 0 1 1 1 0 Ycf1 Glyco_transf_15 PF01793.11 CDJ66067.1 - 1.1 8.1 9.1 1.2 8.0 6.3 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Pex16 PF08610.5 CDJ66067.1 - 1.1 8.1 8.0 1.1 8.1 5.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Neur_chan_memb PF02932.11 CDJ66067.1 - 1.9 8.2 9.5 2.2 8.1 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2217 PF10265.4 CDJ66067.1 - 2.3 6.8 7.2 2.7 6.6 5.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) G-alpha PF00503.15 CDJ66067.1 - 2.6 6.6 9.0 2.9 6.5 6.2 1.2 1 0 0 1 1 1 0 G-protein alpha subunit CDC45 PF02724.9 CDJ66067.1 - 2.6 5.9 10.4 2.7 5.9 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DHHW PF14286.1 CDJ66067.1 - 2.7 7.2 8.1 3.4 6.8 5.6 1.2 1 0 0 1 1 1 0 DHHW protein Hid1 PF12722.2 CDJ66067.1 - 3.5 5.1 12.5 3.8 5.0 8.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDJ66067.1 - 3.6 5.9 8.3 3.7 5.8 5.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hom_end_hint PF05203.11 CDJ66067.1 - 6 6.5 8.1 7.8 6.1 5.6 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Senescence_reg PF04520.8 CDJ66067.1 - 7 7.1 13.6 10 6.6 9.4 1.2 1 0 0 1 1 1 0 Senescence regulator eIF-3_zeta PF05091.7 CDJ66067.1 - 7.8 4.9 19.6 8.4 4.8 13.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIH1 PF08190.7 CDJ66067.1 - 8.3 5.7 17.5 10 5.4 12.1 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF935 PF06074.7 CDJ66067.1 - 8.5 4.9 19.6 13 4.3 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF912 PF06024.7 CDJ66067.1 - 9.4 6.3 11.7 29 4.7 7.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Na_H_Exchanger PF00999.16 CDJ66068.1 - 5.6e-13 48.1 6.7 2.9e-09 35.9 1.9 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family ACDC PF14733.1 CDJ66069.1 - 9.8e-10 38.4 0.5 9.8e-10 38.4 0.3 1.7 2 0 0 2 2 2 1 AP2-coincident C-terminal Gly-zipper_OmpA PF13436.1 CDJ66071.1 - 0.13 11.9 8.1 0.32 10.6 5.6 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PAT1 PF09770.4 CDJ66071.1 - 2.6 6.1 21.5 2.7 6.1 14.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ66071.1 - 2.8 6.0 31.5 3.7 5.6 21.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDJ66071.1 - 3 7.5 21.6 12 5.6 15.0 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA TFIIA PF03153.8 CDJ66071.1 - 5.2 6.8 12.0 5.8 6.7 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ66072.1 - 0.027 12.7 40.1 0.029 12.6 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDJ66072.1 - 0.04 13.7 4.4 0.047 13.5 3.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LIN37 PF15306.1 CDJ66072.1 - 0.098 12.6 13.8 0.14 12.1 9.6 1.2 1 0 0 1 1 1 0 LIN37 US22 PF02393.11 CDJ66072.1 - 0.32 11.0 2.3 2.6 8.0 1.0 2.3 2 1 0 2 2 2 0 US22 like BSMAP PF12280.3 CDJ66072.1 - 0.81 9.5 11.8 1.2 8.9 8.2 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein Hid1 PF12722.2 CDJ66072.1 - 1.3 6.6 10.1 1.4 6.4 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.1 CDJ66072.1 - 1.3 7.2 11.2 1.6 6.9 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.5 CDJ66072.1 - 2.9 6.2 14.4 3 6.1 10.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_DNAp_acc PF04929.7 CDJ66072.1 - 7.3 5.4 10.9 8.5 5.2 7.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SPX PF03105.14 CDJ66073.1 - 0.021 14.6 9.5 0.021 14.6 1.2 2.1 2 0 0 2 2 2 0 SPX domain DUF3173 PF11372.3 CDJ66073.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) BTV_NS2 PF04514.7 CDJ66073.1 - 0.12 11.2 1.8 0.19 10.5 1.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Macoilin PF09726.4 CDJ66073.1 - 0.16 10.2 31.6 0.06 11.6 11.6 2.1 2 0 0 2 2 2 0 Transmembrane protein DUF4614 PF15391.1 CDJ66073.1 - 0.25 11.0 34.4 0.78 9.4 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 CDJ66073.1 - 0.31 9.8 27.9 0.72 8.6 11.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.4 CDJ66073.1 - 0.46 9.0 14.8 0.028 13.0 4.2 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DDHD PF02862.12 CDJ66073.1 - 1.3 8.7 17.0 1.2 8.8 4.8 2.2 2 0 0 2 2 2 0 DDHD domain DUF2217 PF10265.4 CDJ66073.1 - 1.6 7.3 24.1 0.42 9.3 9.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Sec3_C PF09763.4 CDJ66073.1 - 2 6.4 17.3 1.1 7.2 5.2 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 Vfa1 PF08432.5 CDJ66073.1 - 8.6 6.3 9.1 12 5.8 2.1 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Cnd1 PF12717.2 CDJ66075.1 - 8.7e-05 22.4 0.4 0.00016 21.6 0.1 1.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CDJ66075.1 - 0.0061 16.5 4.2 1.4 9.1 0.1 3.3 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.15 CDJ66075.1 - 0.017 13.4 0.2 0.023 13.0 0.1 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Nipped-B_C PF12830.2 CDJ66075.1 - 0.23 11.0 1.3 3.6 7.1 0.1 2.6 1 1 1 2 2 2 0 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.1 CDJ66075.1 - 0.64 10.5 4.4 7.8 7.1 0.3 3.2 2 1 1 3 3 3 0 HEAT-like repeat zf-U1 PF06220.7 CDJ66076.1 - 1.4e-17 62.9 1.5 1.9e-17 62.4 1.0 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CDJ66076.1 - 0.00053 20.0 1.5 0.001 19.1 1.0 1.5 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 CDJ66076.1 - 0.023 14.4 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF1891 PF09004.5 CDJ66077.1 - 0.19 11.1 1.1 0.35 10.2 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) SAGA-Tad1 PF12767.2 CDJ66079.1 - 0.024 14.3 24.0 0.032 13.9 16.6 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SOBP PF15279.1 CDJ66079.1 - 0.078 13.3 24.5 0.096 13.0 17.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein LMBR1 PF04791.11 CDJ66079.1 - 0.19 10.3 12.8 0.2 10.2 8.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PLRV_ORF5 PF01690.12 CDJ66079.1 - 0.2 10.7 20.4 0.28 10.2 14.1 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CDK5_activator PF03261.10 CDJ66079.1 - 0.44 9.8 21.7 0.53 9.5 15.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein YjgP_YjgQ PF03739.9 CDJ66079.1 - 0.52 9.0 7.1 0.55 8.9 4.9 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family CAF-1_p150 PF11600.3 CDJ66079.1 - 0.91 8.8 37.2 1.4 8.2 25.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDJ66079.1 - 1.3 8.4 47.7 2.8 7.3 33.0 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 CDJ66079.1 - 1.3 6.6 19.1 1.5 6.4 13.2 1.1 1 0 0 1 1 1 0 Ycf1 Hex_IIIa PF02455.11 CDJ66079.1 - 1.9 7.0 21.6 2.3 6.8 14.9 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Parvo_coat PF00740.13 CDJ66079.1 - 1.9 7.3 24.9 2.3 7.0 17.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Peptidase_S64 PF08192.6 CDJ66079.1 - 2.1 6.5 20.8 2.3 6.4 14.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF3337 PF11816.3 CDJ66079.1 - 2.3 7.5 18.9 2.9 7.1 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Spore_YhcN_YlaJ PF09580.5 CDJ66079.1 - 2.6 8.1 21.3 4.8 7.2 14.8 1.5 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) SpoVR PF04293.8 CDJ66079.1 - 2.7 6.2 17.5 3.2 6.0 12.1 1.2 1 0 0 1 1 1 0 SpoVR like protein Asp-B-Hydro_N PF05279.6 CDJ66079.1 - 3 7.6 17.8 4.4 7.0 12.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Cellulose_synt PF03552.9 CDJ66079.1 - 4.8 5.3 7.2 5.5 5.1 5.0 1.1 1 0 0 1 1 1 0 Cellulose synthase eIF-3_zeta PF05091.7 CDJ66079.1 - 5.1 5.6 28.2 6.8 5.1 19.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 CDJ66079.1 - 9.3 3.7 25.5 11 3.5 17.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein KH_1 PF00013.24 CDJ66081.1 - 7e-40 134.4 0.6 3.2e-13 49.1 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CDJ66081.1 - 1.5e-32 110.6 1.9 3.6e-11 42.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CDJ66081.1 - 3.6e-12 45.6 2.9 0.00023 20.6 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CDJ66081.1 - 2.3e-05 23.9 0.1 0.98 9.1 0.0 3.5 3 0 0 3 3 3 1 KH domain KH_5 PF13184.1 CDJ66081.1 - 0.0002 21.1 2.1 1.6 8.5 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain Spt20 PF12090.3 CDJ66081.1 - 0.024 13.9 10.5 0.2 11.0 1.7 2.2 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDJ66081.1 - 0.11 11.5 16.5 0.43 9.5 2.9 2.8 3 0 0 3 3 3 0 Fms-interacting protein TMEM171 PF15471.1 CDJ66081.1 - 0.12 11.1 5.6 0.5 9.1 0.4 2.2 2 0 0 2 2 2 0 Transmembrane protein family 171 SPX PF03105.14 CDJ66081.1 - 0.24 11.1 6.4 0.089 12.5 0.8 2.0 2 0 0 2 2 2 0 SPX domain Hemocyanin_C PF03723.9 CDJ66081.1 - 0.38 9.8 1.8 0.29 10.2 0.1 1.6 2 0 0 2 2 2 0 Hemocyanin, ig-like domain TMEM223 PF14640.1 CDJ66081.1 - 0.41 10.5 2.6 0.99 9.3 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein 223 Pex14_N PF04695.8 CDJ66081.1 - 0.41 10.6 11.3 0.47 10.4 1.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAB3GAP2_N PF14655.1 CDJ66081.1 - 0.79 8.6 13.8 0.42 9.5 2.2 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDJ66081.1 - 1.1 8.9 10.7 3.2 7.4 2.1 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ66081.1 - 1.6 6.8 27.3 1 7.5 3.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDJ66081.1 - 4.2 7.1 22.0 0.51 10.1 5.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF853 PF05872.7 CDJ66081.1 - 4.7 5.4 13.8 5.1 5.3 4.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Activator_LAG-3 PF11498.3 CDJ66081.1 - 5.8 5.5 44.9 0.3 9.7 11.5 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF3371 PF11851.3 CDJ66081.1 - 6.1 7.5 16.3 4.7 7.8 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) PHD_3 PF13922.1 CDJ66081.1 - 7.2 6.9 24.8 2.4 8.4 5.5 3.1 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx APC_CDC26 PF10471.4 CDJ66081.1 - 8.4 7.2 29.7 15 6.3 6.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Ctr PF04145.10 CDJ66081.1 - 9.7 6.2 6.1 6.4 6.8 0.5 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Tcf25 PF04910.9 CDJ66084.1 - 6.8e-54 183.1 2.7 1e-53 182.5 1.9 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PITH PF06201.8 CDJ66085.1 - 8.1e-25 87.3 0.0 1.4e-23 83.3 0.0 2.0 1 1 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 CDJ66086.1 - 6.1e-20 70.8 0.5 7.3e-20 70.6 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CDJ66086.1 - 0.0016 18.5 0.0 0.01 15.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDJ66086.1 - 0.0035 17.4 0.1 0.0075 16.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like KaiB PF07689.7 CDJ66086.1 - 0.03 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 KaiB domain Thioredoxin_7 PF13899.1 CDJ66086.1 - 0.044 13.8 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.11 CDJ66086.1 - 0.08 11.6 0.0 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 Phosducin CS PF04969.11 CDJ66087.1 - 6.7e-07 29.7 0.0 2.8e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 CS domain CK_II_beta PF01214.13 CDJ66088.1 - 4.7e-64 215.2 0.5 1e-63 214.1 0.0 1.8 3 0 0 3 3 3 1 Casein kinase II regulatory subunit Nucleoplasmin PF03066.10 CDJ66088.1 - 0.12 11.9 5.0 0.27 10.7 3.5 1.6 1 0 0 1 1 1 0 Nucleoplasmin AF1Q PF15017.1 CDJ66088.1 - 0.13 12.1 5.5 0.28 11.0 3.8 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Myc_N PF01056.13 CDJ66088.1 - 0.4 9.7 5.6 0.65 9.0 3.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region AAA_33 PF13671.1 CDJ66089.1 - 1.2e-24 86.8 0.0 2.6e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain SPRY PF00622.23 CDJ66089.1 - 2.2e-19 69.7 0.0 8.8e-19 67.8 0.0 2.1 1 0 0 1 1 1 1 SPRY domain Zeta_toxin PF06414.7 CDJ66089.1 - 0.072 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CDJ66089.1 - 0.092 13.0 0.0 0.33 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Peptidase_M28 PF04389.12 CDJ66090.1 - 1.2e-22 80.4 0.0 2.5e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CDJ66090.1 - 0.052 13.0 0.0 0.87 9.0 0.0 2.9 2 2 0 2 2 2 0 Peptidase family M20/M25/M40 Metallophos PF00149.23 CDJ66091.1 - 7.7e-34 116.8 0.0 1.1e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CDJ66091.1 - 3e-21 74.8 2.1 2.7e-16 58.9 0.3 2.8 2 1 2 4 4 4 3 TPR repeat PPP5 PF08321.7 CDJ66091.1 - 4.3e-15 55.4 0.0 1.1e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.12 CDJ66091.1 - 1.2e-13 49.8 5.8 0.00018 21.1 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ66091.1 - 3.4e-13 48.5 5.2 8.8e-05 21.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ66091.1 - 1.1e-05 25.2 2.6 0.00012 21.9 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ66091.1 - 0.00013 22.5 5.7 0.089 13.4 0.4 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ66091.1 - 0.0018 18.3 1.3 0.031 14.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ66091.1 - 0.0085 15.9 0.1 6.6 6.6 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ66091.1 - 0.012 16.2 7.8 4 8.3 0.0 4.4 3 1 2 5 5 4 0 Tetratricopeptide repeat NYD-SP12_N PF15015.1 CDJ66091.1 - 0.071 11.3 0.1 0.13 10.5 0.1 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal MIF PF01187.13 CDJ66092.1 - 1.5e-19 70.1 0.1 1.6e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 CDJ66092.1 - 0.0049 16.4 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme DUF4210 PF13915.1 CDJ66092.1 - 0.14 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) BNR PF02012.15 CDJ66093.1 - 8.4e-07 27.8 13.0 0.24 11.3 0.1 6.6 6 0 0 6 6 6 3 BNR/Asp-box repeat BNR_2 PF13088.1 CDJ66093.1 - 0.00036 19.9 0.0 2.1 7.5 0.0 3.6 3 0 0 3 3 3 3 BNR repeat-like domain CDK5_activator PF03261.10 CDJ66095.1 - 0.19 11.0 14.0 0.21 10.8 9.7 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein EIF4E-T PF10477.4 CDJ66095.1 - 1.1 7.9 14.3 1.3 7.7 9.9 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SprA-related PF12118.3 CDJ66095.1 - 1.2 8.4 29.4 1.4 8.1 20.4 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 CDJ66095.1 - 1.4 8.7 8.0 1.6 8.5 5.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SR-25 PF10500.4 CDJ66095.1 - 2.7 7.4 18.1 3.4 7.0 12.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1644 PF07800.7 CDJ66095.1 - 3.3 7.5 16.5 1.7 8.4 9.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) RNA_pol_Rpb1_5 PF04998.12 CDJ66095.1 - 3.4 6.8 7.4 4.1 6.5 5.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Pex14_N PF04695.8 CDJ66095.1 - 3.9 7.5 19.1 6.1 6.8 13.0 1.5 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FLO_LFY PF01698.11 CDJ66095.1 - 4.3 6.0 13.0 5 5.8 9.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Hamartin PF04388.7 CDJ66095.1 - 5.3 5.5 12.4 5.2 5.6 8.6 1.0 1 0 0 1 1 1 0 Hamartin protein DUF1800 PF08811.6 CDJ66095.1 - 5.4 5.8 16.1 6.4 5.5 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) P5-ATPase PF12409.3 CDJ66095.1 - 5.5 6.8 5.5 7.1 6.5 3.8 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter R_equi_Vir PF05526.6 CDJ66095.1 - 6.3 6.3 9.5 8.4 5.9 6.6 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DDHD PF02862.12 CDJ66095.1 - 6.4 6.4 13.3 7.6 6.2 9.3 1.1 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 CDJ66095.1 - 9.8 4.2 26.8 11 4.1 18.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec3_C PF09763.4 CDJ66096.1 - 0.0027 15.9 1.8 0.0027 15.9 1.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Orai-1 PF07856.7 CDJ66096.1 - 0.0052 16.3 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity FAM176 PF14851.1 CDJ66096.1 - 0.012 15.2 0.2 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.12 CDJ66096.1 - 0.058 13.1 6.2 0.072 12.8 4.3 1.1 1 0 0 1 1 1 0 DDHD domain Tmemb_cc2 PF10267.4 CDJ66096.1 - 0.17 10.4 6.7 0.17 10.4 4.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pex14_N PF04695.8 CDJ66096.1 - 0.36 10.8 12.3 0.61 10.1 8.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.12 CDJ66096.1 - 1.9 7.1 5.0 2.5 6.8 3.4 1.2 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 CDJ66096.1 - 2.2 6.4 25.2 2.7 6.1 17.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Secretin_N_2 PF07655.8 CDJ66096.1 - 4 7.9 35.7 6.5 7.2 24.7 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Inp1 PF12634.2 CDJ66096.1 - 9.1 5.9 10.3 18 5.0 7.1 1.5 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 DNA_pol_viral_N PF00242.12 CDJ66096.1 - 9.5 5.1 20.4 12 4.7 14.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Mitofilin PF09731.4 CDJ66097.1 - 6.9e-06 25.0 0.0 6.9e-06 25.0 0.0 3.5 1 1 1 2 2 2 1 Mitochondrial inner membrane protein Parvo_coat PF00740.13 CDJ66097.1 - 0.016 14.1 13.0 0.024 13.5 9.0 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Hid1 PF12722.2 CDJ66097.1 - 0.64 7.6 22.6 0.87 7.1 15.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 CDJ66097.1 - 2 6.6 5.3 2.8 6.1 3.7 1.2 1 0 0 1 1 1 0 Membrane transport protein Plasmodium_Vir PF05795.6 CDJ66097.1 - 2.2 7.3 7.1 4.5 6.3 4.9 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein YjgP_YjgQ PF03739.9 CDJ66097.1 - 7.5 5.1 6.8 12 4.5 4.7 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Cellulose_synt PF03552.9 CDJ66097.1 - 8.4 4.5 8.0 13 3.8 5.5 1.2 1 0 0 1 1 1 0 Cellulose synthase SelR PF01641.13 CDJ66098.1 - 4e-16 58.8 0.1 4.8e-16 58.5 0.1 1.0 1 0 0 1 1 1 1 SelR domain Pyr_redox_2 PF07992.9 CDJ66099.1 - 5.6e-27 94.9 0.0 7.1e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDJ66099.1 - 1.8e-15 57.0 1.2 6.5e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDJ66099.1 - 1.7e-12 47.8 0.0 2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CDJ66099.1 - 8.7e-08 31.6 0.0 1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CDJ66099.1 - 0.00028 19.8 4.4 0.0019 17.1 2.1 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 CDJ66099.1 - 0.00044 19.2 1.9 0.00044 19.2 1.3 2.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 CDJ66099.1 - 0.00045 19.4 0.4 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CDJ66099.1 - 0.00057 19.6 0.5 0.77 9.4 0.0 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 CDJ66099.1 - 0.00066 18.2 0.5 0.02 13.4 0.4 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 CDJ66099.1 - 0.001 19.2 0.3 0.94 9.7 0.1 2.8 2 1 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.19 CDJ66099.1 - 0.0012 17.7 2.8 0.043 12.6 1.5 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CDJ66099.1 - 0.0016 17.5 0.1 0.0031 16.6 0.1 1.5 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 CDJ66099.1 - 0.002 17.8 3.7 0.27 10.8 0.0 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 CDJ66099.1 - 0.0054 16.7 0.5 0.0054 16.7 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CDJ66099.1 - 0.0091 14.9 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.1 CDJ66099.1 - 0.048 13.9 0.2 4.4 7.6 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain F420_oxidored PF03807.12 CDJ66099.1 - 0.076 13.4 1.8 31 5.0 0.3 3.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.14 CDJ66099.1 - 0.094 11.7 1.6 3 6.7 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 CDJ66099.1 - 1.5 7.6 4.0 0.23 10.3 0.2 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein Herpes_UL87 PF03043.9 CDJ66100.1 - 8.7e-05 21.0 0.6 0.92 7.8 0.3 4.0 3 2 0 4 4 4 2 Herpesvirus UL87 family GATase PF00117.23 CDJ66101.1 - 1e-31 109.9 0.0 2.6e-31 108.5 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CDJ66101.1 - 7e-07 28.9 2.9 1.3e-06 28.0 0.0 2.6 2 1 0 2 2 2 1 Peptidase C26 Asn_synthase PF00733.16 CDJ66101.1 - 5.5e-06 26.0 0.6 3.9e-05 23.2 0.0 2.4 3 0 0 3 3 3 1 Asparagine synthase NAD_synthase PF02540.12 CDJ66101.1 - 0.00031 19.7 0.0 0.00069 18.5 0.0 1.5 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 CDJ66101.1 - 0.0012 17.4 0.0 0.0012 17.4 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase TSA PF03249.8 CDJ66101.1 - 0.0043 15.6 11.7 0.0043 15.6 8.1 1.5 2 0 0 2 2 2 1 Type specific antigen PAPS_reduct PF01507.14 CDJ66101.1 - 0.019 14.7 0.2 0.17 11.6 0.0 2.3 3 0 0 3 3 3 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.9 CDJ66101.1 - 0.11 11.9 0.8 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) DUF1448 PF07289.6 CDJ66101.1 - 0.18 10.6 2.4 0.31 9.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) Secretin_N_2 PF07655.8 CDJ66102.1 - 0.29 11.5 14.4 0.43 11.0 10.0 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Apt1 PF10351.4 CDJ66102.1 - 0.39 9.5 6.3 0.47 9.2 4.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF566 PF04484.7 CDJ66102.1 - 0.92 8.9 14.7 1.2 8.5 10.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 CDJ66102.1 - 1.5 7.0 13.1 1.7 6.7 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 CDJ66102.1 - 2.2 7.7 10.2 2.9 7.3 7.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Period_C PF12114.3 CDJ66102.1 - 2.4 7.7 17.7 3.4 7.2 12.3 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CAF-1_p150 PF11600.3 CDJ66102.1 - 3.2 7.0 9.9 4.1 6.7 6.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Corona_nucleoca PF00937.13 CDJ66102.1 - 3.3 6.5 9.5 3.9 6.3 6.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3633 PF12315.3 CDJ66102.1 - 3.8 6.7 6.5 6.4 6.0 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) DUF2217 PF10265.4 CDJ66102.1 - 6 5.5 9.3 6.8 5.3 6.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4054 PF13262.1 CDJ66102.1 - 6.9 6.9 8.7 11 6.2 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) DUF3446 PF11928.3 CDJ66103.1 - 0.067 13.3 5.6 0.13 12.4 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF1517 PF07466.6 CDJ66103.1 - 1.8 7.4 4.7 2.3 7.1 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Med15 PF09606.5 CDJ66104.1 - 0.0053 15.0 9.4 0.0074 14.5 6.5 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3323 PF11796.3 CDJ66104.1 - 0.06 12.6 10.7 0.48 9.7 7.4 2.0 1 1 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DUF3530 PF12048.3 CDJ66104.1 - 7.5 5.4 11.1 0.25 10.2 3.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Pkinase PF00069.20 CDJ66105.1 - 1.3e-37 129.4 0.0 3.2e-27 95.2 0.0 4.0 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ66105.1 - 3.9e-13 49.0 0.0 4e-07 29.3 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase DUF755 PF05501.6 CDJ66105.1 - 0.004 17.2 2.1 0.004 17.2 1.4 7.3 8 0 0 8 8 8 1 Domain of unknown function (DUF755) Seadorna_VP7 PF07387.6 CDJ66105.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 zf-DHHC PF01529.15 CDJ66105.1 - 0.16 11.3 0.6 15 4.9 0.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Ycf1 PF05758.7 CDJ66105.1 - 8.7 3.9 11.3 3.8 5.0 3.5 2.1 2 0 0 2 2 2 0 Ycf1 Pkinase PF00069.20 CDJ66106.1 - 1.7e-06 27.3 0.0 5e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ66106.1 - 0.0022 17.1 0.0 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BAF1_ABF1 PF04684.8 CDJ66106.1 - 0.0029 16.5 22.6 0.0029 16.5 15.6 2.3 2 1 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDJ66106.1 - 0.073 13.3 20.0 0.22 11.7 9.3 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Suf PF05843.9 CDJ66106.1 - 0.89 9.2 6.4 1.8 8.2 4.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SpaB_C PF14028.1 CDJ66106.1 - 4.9 6.6 12.5 1.9 7.9 1.8 2.4 2 0 0 2 2 2 0 SpaB C-terminal domain DUF3008 PF11450.3 CDJ66108.1 - 0.026 14.6 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) Ribosomal_60s PF00428.14 CDJ66110.1 - 0.012 16.0 0.6 0.022 15.1 0.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ66111.1 - 0.46 9.9 54.4 1.3 8.4 8.7 3.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PP2C PF00481.16 CDJ66112.1 - 7.5e-13 48.4 0.1 1.2e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C FimP PF09766.4 CDJ66113.1 - 4 6.4 25.5 4.2 6.3 17.7 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF3381 PF11861.3 CDJ66113.1 - 4.9 6.6 11.6 5.2 6.5 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Trypan_glycop_C PF10659.4 CDJ66113.1 - 5.9 7.2 9.9 6.5 7.1 6.9 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain RRP14 PF15459.1 CDJ66113.1 - 6.2 6.9 13.3 8.5 6.5 9.2 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 eIF3_subunit PF08597.5 CDJ66113.1 - 6.6 6.2 12.1 6.9 6.1 8.4 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2149 PF09919.4 CDJ66113.1 - 7.4 6.7 9.7 8.9 6.4 6.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) RNA_pol_Rpc4 PF05132.9 CDJ66113.1 - 7.8 6.5 12.0 7.6 6.5 8.3 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_S49_N PF08496.5 CDJ66113.1 - 8.2 6.2 10.0 8.8 6.0 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDRGK PF09756.4 CDJ66113.1 - 8.8 5.6 17.9 9.9 5.5 12.4 1.0 1 0 0 1 1 1 0 DDRGK domain CagX PF03524.10 CDJ66113.1 - 9.3 5.4 12.7 10 5.2 8.8 1.0 1 0 0 1 1 1 0 Conjugal transfer protein DUF1764 PF08576.5 CDJ66113.1 - 9.7 7.0 14.6 12 6.7 10.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) His_Phos_1 PF00300.17 CDJ66114.1 - 1.9e-05 24.8 0.1 1.9e-05 24.8 0.1 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Spt20 PF12090.3 CDJ66114.1 - 0.034 13.4 0.1 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDJ66114.1 - 0.079 12.6 1.3 0.1 12.3 0.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2802 PF10975.3 CDJ66114.1 - 0.097 12.4 6.2 0.2 11.4 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DUF4366 PF14283.1 CDJ66114.1 - 0.49 9.7 5.4 0.68 9.3 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Alpha_GJ PF03229.8 CDJ66114.1 - 0.98 9.7 19.9 1.7 8.9 13.8 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J APC_CDC26 PF10471.4 CDJ66114.1 - 3.9 8.2 17.7 0.59 10.9 7.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 SR-25 PF10500.4 CDJ66115.1 - 5.4e-05 22.7 13.0 5.4e-05 22.7 9.0 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ66115.1 - 0.026 13.9 12.9 0.058 12.7 8.9 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3801 PF12687.2 CDJ66115.1 - 3.8 7.0 10.2 6.9 6.1 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DDHD PF02862.12 CDJ66115.1 - 8.3 6.1 12.2 0.53 10.0 3.7 2.1 2 0 0 2 2 2 0 DDHD domain POP1 PF06978.6 CDJ66116.1 - 7.6e-13 48.5 12.4 2.5e-11 43.6 0.0 2.8 3 0 0 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 DUF2217 PF10265.4 CDJ66116.1 - 0.21 10.2 3.3 0.46 9.1 2.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Vpu PF00558.14 CDJ66116.1 - 0.25 10.9 0.0 0.93 9.0 0.1 1.8 2 0 0 2 2 2 0 Vpu protein POPLD PF08170.7 CDJ66116.1 - 0.4 10.5 0.0 0.4 10.5 0.0 3.1 3 0 0 3 3 3 0 POPLD (NUC188) domain Pex14_N PF04695.8 CDJ66116.1 - 1.8 8.6 23.7 0.92 9.5 7.7 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDJ66116.1 - 5.3 6.6 14.3 3 7.5 4.7 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF779 PF05610.6 CDJ66117.1 - 0.086 12.8 0.2 0.19 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF779) Anticodon_1 PF08264.8 CDJ66119.1 - 0.11 12.2 1.2 5 6.8 0.0 2.2 1 1 0 2 2 2 0 Anticodon-binding domain of tRNA EF-hand_1 PF00036.27 CDJ66120.1 - 1.5e-09 36.4 0.1 1.3e-06 27.2 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CDJ66120.1 - 1.6e-08 33.7 0.6 4.6e-05 22.9 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 CDJ66120.1 - 4.1e-08 33.2 0.0 0.00051 20.1 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDJ66120.1 - 1.5e-05 24.5 0.0 0.23 11.1 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain pair Dehydrin PF00257.14 CDJ66120.1 - 2.5e-05 24.6 0.2 2.5e-05 24.6 0.2 6.5 2 1 2 4 4 4 1 Dehydrin EF-hand_5 PF13202.1 CDJ66120.1 - 0.00013 21.1 1.8 0.00057 19.1 0.0 2.7 3 0 0 3 3 3 1 EF hand RskA PF10099.4 CDJ66120.1 - 0.002 17.8 0.9 0.002 17.8 0.6 5.0 2 1 0 2 2 2 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.14 CDJ66120.1 - 1.8 9.0 22.5 8.3 6.8 2.1 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ66121.1 - 0.0065 15.9 25.0 0.0065 15.9 17.3 5.8 2 1 3 5 5 5 1 Nuclear RNA-splicing-associated protein Coa1 PF08695.5 CDJ66122.1 - 0.047 13.1 0.5 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 SR-25 PF10500.4 CDJ66122.1 - 0.051 13.0 8.9 0.07 12.5 6.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP_bind_2 PF03668.10 CDJ66125.1 - 0.077 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop ATPase protein family TSA PF03249.8 CDJ66125.1 - 0.095 11.2 4.9 0.18 10.3 3.4 1.5 1 0 0 1 1 1 0 Type specific antigen DUF4661 PF15576.1 CDJ66125.1 - 0.99 8.9 6.6 7.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) CcmD PF04995.9 CDJ66126.1 - 0.0034 17.0 2.4 0.0034 17.0 1.7 7.6 4 2 0 4 4 4 1 Heme exporter protein D (CcmD) DUF3357 PF11837.3 CDJ66126.1 - 0.059 13.2 0.4 0.059 13.2 0.3 5.1 4 2 0 4 4 4 0 Domain of unknown function (DUF3357) OppC_N PF12911.2 CDJ66126.1 - 0.068 12.5 0.0 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1510 PF07423.6 CDJ66126.1 - 1.6 8.0 40.8 1.7 7.9 11.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) LRR_4 PF12799.2 CDJ66127.1 - 2.7e-19 68.3 36.8 5.3e-08 32.3 3.8 4.4 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ66127.1 - 4.3e-14 52.0 17.6 7.9e-11 41.5 5.9 3.6 1 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CDJ66127.1 - 2.7e-09 35.7 18.1 0.0061 16.4 0.6 6.7 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 CDJ66127.1 - 2.7e-07 29.9 16.6 0.089 12.9 0.2 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 CDJ66127.1 - 7.3e-06 25.3 26.2 0.041 14.0 0.2 6.0 6 0 0 6 6 6 3 Leucine rich repeat EcsC PF12787.2 CDJ66127.1 - 0.13 11.6 1.7 0.2 10.9 1.2 1.3 1 0 0 1 1 1 0 EcsC protein family LRR_9 PF14580.1 CDJ66127.1 - 0.28 10.7 4.0 0.75 9.3 1.5 2.0 1 1 1 2 2 2 0 Leucine-rich repeat TraG_N PF07916.6 CDJ66127.1 - 1.8 6.9 7.9 2.4 6.5 5.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region CDK2AP PF09806.4 CDJ66127.1 - 7.1 6.8 10.0 20 5.3 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PIP5K PF01504.13 CDJ66128.1 - 1.8e-64 217.2 0.0 2.8e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.27 CDJ66128.1 - 8.8e-05 21.5 0.3 0.00034 19.6 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CDJ66128.1 - 0.0034 17.4 0.1 0.0097 16.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CDJ66128.1 - 0.013 15.2 1.0 0.039 13.8 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 CDJ66128.1 - 0.075 12.6 1.2 0.18 11.4 0.4 1.9 2 0 0 2 2 2 0 EF-hand domain pair RRM_1 PF00076.17 CDJ66129.1 - 1.2e-06 28.0 0.0 2.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ66129.1 - 1.3e-06 28.0 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ66129.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lipoprotein_8 PF02030.10 CDJ66129.1 - 0.0095 14.4 0.1 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical lipoprotein (MG045 family) DUF1866 PF08952.6 CDJ66129.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) DUF2201_N PF13203.1 CDJ66129.1 - 1.1 8.4 8.1 0.082 12.0 2.5 1.4 2 0 0 2 2 2 0 Putative metallopeptidase domain RBM39linker PF15519.1 CDJ66129.1 - 5.5 7.3 9.7 3 8.1 2.3 3.0 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein RRM_1 PF00076.17 CDJ66130.1 - 6.1e-26 89.8 0.0 4.2e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ66130.1 - 1.7e-20 72.7 0.0 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ66130.1 - 9e-14 51.0 0.0 6.1e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 CDJ66131.1 - 0.0015 18.5 16.6 0.0015 18.5 11.5 2.8 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region LMBR1 PF04791.11 CDJ66131.1 - 0.076 11.5 0.0 0.1 11.1 0.0 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein SID-1_RNA_chan PF13965.1 CDJ66131.1 - 0.49 8.5 5.1 0.74 7.9 3.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folate_carrier PF01770.13 CDJ66131.1 - 0.66 8.4 10.3 1.6 7.2 7.1 1.6 1 0 0 1 1 1 0 Reduced folate carrier Spore_coat_CotO PF14153.1 CDJ66131.1 - 0.92 8.9 26.6 0.024 14.0 11.8 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Dynamin_N PF00350.18 CDJ66131.1 - 1.8 8.3 8.5 0.86 9.4 4.1 1.8 2 0 0 2 2 2 0 Dynamin family RED_N PF07808.8 CDJ66131.1 - 2 7.5 26.3 0.054 12.7 10.8 2.4 2 0 0 2 2 2 0 RED-like protein N-terminal region Cellulose_synt PF03552.9 CDJ66131.1 - 2.2 6.4 6.4 3.5 5.8 4.4 1.3 1 0 0 1 1 1 0 Cellulose synthase eIF-3_zeta PF05091.7 CDJ66131.1 - 2.6 6.5 22.4 0.38 9.3 12.1 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Baculo_PP31 PF05311.6 CDJ66131.1 - 3.2 6.9 18.2 0.79 8.9 8.4 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DDHD PF02862.12 CDJ66131.1 - 3.9 7.2 20.4 0.45 10.2 9.3 2.1 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.1 CDJ66131.1 - 4.6 7.4 16.7 0.98 9.5 7.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.2 CDJ66131.1 - 4.9 4.6 17.9 0.018 12.7 5.8 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Peptidase_S49_N PF08496.5 CDJ66131.1 - 6 6.6 19.0 0.32 10.7 7.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FAM176 PF14851.1 CDJ66131.1 - 7.2 6.2 11.1 0.98 9.0 4.0 2.2 2 0 0 2 2 2 0 FAM176 family AAA_23 PF13476.1 CDJ66131.1 - 7.2 6.8 29.4 5.4 7.2 15.0 2.1 2 0 0 2 2 2 0 AAA domain Suf PF05843.9 CDJ66131.1 - 8.2 6.0 32.2 0.014 15.1 12.1 2.4 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) AUX_IAA PF02309.11 CDJ66131.1 - 9.8 5.8 15.3 1.1 8.9 7.0 1.9 2 0 0 2 2 2 0 AUX/IAA family DUF4259 PF14078.1 CDJ66132.1 - 0.0025 18.3 1.7 2.9 8.3 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4259) DUF3091 PF11291.3 CDJ66132.1 - 0.054 13.4 1.2 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) DUF372 PF04036.7 CDJ66132.1 - 0.082 12.3 3.0 7 6.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF372) Glyco_transf_49 PF13896.1 CDJ66132.1 - 0.093 11.8 0.7 8.8 5.3 0.1 2.2 2 0 0 2 2 2 0 Glycosyl-transferase for dystroglycan Guanylate_kin PF00625.16 CDJ66132.1 - 0.11 11.9 0.3 16 4.8 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase UBA_2 PF08587.6 CDJ66132.1 - 0.15 12.3 0.3 41 4.4 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) K_channel_TID PF07941.6 CDJ66132.1 - 0.81 9.9 13.0 0.3 11.3 3.6 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4414 PF14377.1 CDJ66132.1 - 1.1 9.2 6.0 12 5.9 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Intimin_C PF07979.6 CDJ66132.1 - 1.3 9.2 3.5 18 5.6 0.1 3.4 4 1 1 5 5 5 0 Intimin C-type lectin domain DUF2989 PF11207.3 CDJ66132.1 - 3.7 6.9 12.0 2 7.8 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2989) Surface_antigen PF11054.3 CDJ66133.1 - 1.7e-63 214.3 5.4 5.4e-54 183.2 0.3 2.0 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen Ank_2 PF12796.2 CDJ66134.1 - 3.3e-30 104.2 0.8 6.9e-16 58.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ66134.1 - 6.9e-26 88.7 4.2 7.5e-08 31.8 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 CDJ66134.1 - 4.8e-20 71.5 3.3 3.5e-10 40.1 0.1 4.8 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ66134.1 - 1.2e-13 49.8 2.0 0.0042 17.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CDJ66134.1 - 1.7e-11 43.9 1.1 1.9e-09 37.4 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Plasmodium_Vir PF05795.6 CDJ66134.1 - 0.54 9.3 2.1 0.76 8.9 1.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDHD PF02862.12 CDJ66134.1 - 1.1 9.0 5.7 1.7 8.3 3.9 1.3 1 0 0 1 1 1 0 DDHD domain MSA-2c PF12238.3 CDJ66134.1 - 1.3 8.6 10.1 2.4 7.7 7.0 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Dsh_C PF12316.3 CDJ66134.1 - 4 7.4 16.7 6.6 6.7 11.6 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.9 CDJ66134.1 - 5.6 4.8 8.7 11 3.9 6.0 1.4 1 0 0 1 1 1 0 CDC45-like protein DASH_Hsk3 PF08227.6 CDJ66136.1 - 0.074 13.2 0.0 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like NUDIX PF00293.23 CDJ66137.1 - 4.9e-14 52.1 0.1 8.6e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Utp14 PF04615.8 CDJ66137.1 - 0.86 7.6 24.0 1.1 7.3 16.6 1.1 1 0 0 1 1 1 0 Utp14 protein MAM33 PF02330.11 CDJ66138.1 - 4e-13 49.6 2.2 1.3e-07 31.6 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein POM121 PF15229.1 CDJ66138.1 - 0.013 14.9 3.2 0.019 14.3 2.2 1.3 1 0 0 1 1 1 0 POM121 family DUF2702 PF10863.3 CDJ66138.1 - 0.062 13.0 3.2 4.1 7.1 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2702) Cauli_DNA-bind PF03310.8 CDJ66138.1 - 0.086 12.6 0.3 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein ecTbetaR2 PF08917.5 CDJ66138.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain AIF_C PF14721.1 CDJ66140.1 - 0.93 9.7 15.5 0.97 9.6 10.7 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2828 PF11443.3 CDJ66140.1 - 1 7.4 15.1 1 7.5 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FYDLN_acid PF09538.5 CDJ66140.1 - 1.4 9.5 8.9 1.5 9.4 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GOLD_2 PF13897.1 CDJ66140.1 - 2.3 8.4 9.7 2.7 8.2 6.8 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Peroxin-13_N PF04088.8 CDJ66140.1 - 2.5 8.0 11.1 2.8 7.8 7.7 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RR_TM4-6 PF06459.7 CDJ66140.1 - 2.6 7.8 18.4 2.6 7.8 12.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CDJ66140.1 - 3.1 6.5 17.4 3.1 6.5 12.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Ctr PF04145.10 CDJ66140.1 - 3.2 7.7 14.2 3.9 7.5 9.9 1.1 1 0 0 1 1 1 0 Ctr copper transporter family RED_N PF07808.8 CDJ66140.1 - 3.2 6.8 29.7 4.2 6.5 20.6 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF1764 PF08576.5 CDJ66140.1 - 3.3 8.5 21.3 3.7 8.3 14.8 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TraH_2 PF06871.6 CDJ66140.1 - 3.3 7.0 9.9 3.5 7.0 6.9 1.1 1 0 0 1 1 1 0 TraH_2 DDHD PF02862.12 CDJ66140.1 - 4.2 7.1 19.7 4.4 7.0 13.6 1.0 1 0 0 1 1 1 0 DDHD domain Dala_Dala_lig_N PF01820.16 CDJ66140.1 - 4.7 7.5 10.6 5.4 7.3 7.4 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus RIC3 PF15361.1 CDJ66140.1 - 5.2 7.2 17.7 6 7.0 12.3 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GAGA_bind PF06217.7 CDJ66140.1 - 5.5 6.8 17.8 5.5 6.8 12.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FAM176 PF14851.1 CDJ66140.1 - 5.5 6.6 12.3 7.4 6.2 8.5 1.2 1 0 0 1 1 1 0 FAM176 family Baculo_PP31 PF05311.6 CDJ66140.1 - 5.6 6.1 20.8 5.9 6.0 14.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gti1_Pac2 PF09729.4 CDJ66140.1 - 6.1 6.6 14.2 6.3 6.6 9.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SpoIIP PF07454.6 CDJ66140.1 - 7 5.7 16.4 7.1 5.7 11.4 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FAM60A PF15396.1 CDJ66140.1 - 7.1 6.3 14.5 7.4 6.2 10.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4512 PF14975.1 CDJ66140.1 - 7.3 7.4 11.7 7.9 7.3 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) PH_4 PF15404.1 CDJ66140.1 - 7.4 6.0 15.6 9.3 5.7 10.8 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain FimP PF09766.4 CDJ66140.1 - 7.7 5.4 34.7 11 4.9 24.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein LIM_bind PF01803.11 CDJ66140.1 - 8.1 5.4 24.9 8.4 5.4 17.3 1.0 1 0 0 1 1 1 0 LIM-domain binding protein DUF3408 PF11888.3 CDJ66140.1 - 8.7 6.2 16.9 11 5.9 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Zip PF02535.17 CDJ66140.1 - 8.8 5.2 8.0 8.7 5.2 5.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.8 CDJ66140.1 - 9 4.9 24.6 9.1 4.8 17.1 1.0 1 0 0 1 1 1 0 Paf1 DUF3449 PF11931.3 CDJ66140.1 - 9 5.7 20.1 9.4 5.6 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) BORG_CEP PF14957.1 CDJ66140.1 - 9.2 7.2 13.6 9.9 7.1 9.4 1.1 1 0 0 1 1 1 0 Cdc42 effector Serinc PF03348.10 CDJ66140.1 - 9.9 4.7 18.8 10 4.7 13.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Slu7 PF11708.3 CDJ66141.1 - 2.4e-54 184.5 25.2 2.4e-52 178.0 16.0 2.5 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.4 CDJ66141.1 - 0.0054 16.2 11.1 0.0054 16.2 7.7 3.2 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2217 PF10265.4 CDJ66141.1 - 1.7 7.2 14.5 0.13 11.0 2.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Retrotrans_gag PF03732.12 CDJ66142.1 - 0.00016 21.6 0.1 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Peroxin-3 PF04882.7 CDJ66143.1 - 6.6e-13 48.1 3.9 6.8e-10 38.2 2.7 2.6 1 1 0 1 1 1 1 Peroxin-3 Dpy19 PF10034.4 CDJ66143.1 - 0.083 11.0 4.1 0.13 10.4 2.8 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation ETRAMP PF09716.5 CDJ66143.1 - 2 8.4 6.2 8.3 6.4 0.3 3.5 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Stig1 PF04885.8 CDJ66143.1 - 2.7 8.2 8.7 2.9 8.1 1.6 2.6 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 DUF2453 PF10507.4 CDJ66144.1 - 2.3e-39 133.6 0.2 2.3e-39 133.6 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2453) GAF_3 PF13492.1 CDJ66144.1 - 0.00016 21.7 0.0 0.0056 16.7 0.0 2.6 2 0 0 2 2 2 1 GAF domain TMEM117 PF15113.1 CDJ66144.1 - 0.027 13.0 2.0 0.04 12.5 1.4 1.1 1 0 0 1 1 1 0 TMEM117 protein family GAF PF01590.21 CDJ66144.1 - 0.033 14.3 4.1 0.049 13.7 0.3 2.9 3 0 0 3 3 3 0 GAF domain DUF2372 PF10178.4 CDJ66146.1 - 0.057 13.5 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) Maf PF02545.9 CDJ66147.1 - 1.3e-19 70.0 0.9 1.9e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 Maf-like protein Med15 PF09606.5 CDJ66147.1 - 3.9 5.5 31.9 5.4 5.0 22.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GATA PF00320.22 CDJ66148.1 - 1.9e-08 33.5 3.8 4.7e-08 32.2 2.6 1.8 1 0 0 1 1 1 1 GATA zinc finger Pyrophosphatase PF00719.14 CDJ66149.1 - 1.6e-12 47.1 0.0 1.5e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Inorganic pyrophosphatase Shisa PF13908.1 CDJ66149.1 - 0.0018 18.4 5.8 0.0061 16.7 4.0 1.9 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Mucin PF01456.12 CDJ66149.1 - 0.0025 17.5 3.6 0.0025 17.5 2.5 3.2 2 1 1 3 3 1 1 Mucin-like glycoprotein Suf PF05843.9 CDJ66149.1 - 0.0041 16.8 0.6 0.0057 16.4 0.4 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) ETRAMP PF09716.5 CDJ66149.1 - 0.0045 16.8 0.1 0.0045 16.8 0.1 3.2 3 1 0 3 3 1 1 Malarial early transcribed membrane protein (ETRAMP) Ycf1 PF05758.7 CDJ66149.1 - 0.0052 14.5 0.0 0.0063 14.2 0.0 1.1 1 0 0 1 1 1 1 Ycf1 DUF1510 PF07423.6 CDJ66149.1 - 0.0057 16.0 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDJ66149.1 - 0.011 15.2 4.1 0.013 14.9 0.1 2.2 2 1 0 2 2 2 0 SpoIIIAH-like protein DUF1183 PF06682.7 CDJ66149.1 - 0.017 14.7 0.1 0.017 14.7 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Neur_chan_memb PF02932.11 CDJ66149.1 - 0.02 14.7 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tetraspannin PF00335.15 CDJ66149.1 - 0.042 13.1 0.8 0.068 12.4 0.6 1.3 1 0 0 1 1 1 0 Tetraspanin family ResB PF05140.9 CDJ66149.1 - 0.13 10.8 2.6 0.19 10.2 1.8 1.2 1 0 0 1 1 1 0 ResB-like family Sarcoglycan_2 PF05510.8 CDJ66149.1 - 0.13 10.5 0.2 0.18 10.0 0.1 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Pex14_N PF04695.8 CDJ66149.1 - 0.44 10.5 13.1 0.033 14.2 4.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RIC3 PF15361.1 CDJ66149.1 - 1.4 9.1 6.1 0.42 10.8 1.5 2.0 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 CYSTM PF12734.2 CDJ66149.1 - 4.8 7.3 18.1 1.7 8.7 2.0 3.2 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance FNIP_N PF14636.1 CDJ66149.1 - 9.4 6.7 11.6 21 5.5 8.1 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Herpes_UL52 PF03121.10 CDJ66150.1 - 7.3e-12 44.8 0.0 2.1e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Mem_trans PF03547.13 CDJ66150.1 - 0.015 13.6 0.1 0.015 13.6 0.0 3.4 3 0 0 3 3 3 0 Membrane transport protein DUF755 PF05501.6 CDJ66154.1 - 1.9 8.5 8.3 3.6 7.6 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RAP1 PF07218.6 CDJ66154.1 - 8.6 4.3 12.2 9.1 4.2 8.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 CDJ66155.1 - 3 7.2 18.5 4.7 6.6 12.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Inositol_P PF00459.20 CDJ66157.1 - 3.4e-15 56.0 0.1 3.4e-15 56.0 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family SR-25 PF10500.4 CDJ66157.1 - 0.00031 20.2 6.5 0.00044 19.7 4.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 CDJ66157.1 - 0.0042 17.4 0.1 0.006 16.9 0.1 1.2 1 0 0 1 1 1 1 Dehydrin Corona_nucleoca PF00937.13 CDJ66157.1 - 0.011 14.6 1.8 0.015 14.2 1.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Period_C PF12114.3 CDJ66157.1 - 0.012 15.1 3.3 0.021 14.4 2.3 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Glyco_hydro_3_C PF01915.17 CDJ66157.1 - 0.087 12.3 1.9 0.11 11.9 1.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF4614 PF15391.1 CDJ66157.1 - 0.42 10.3 8.0 0.61 9.8 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Serglycin PF04360.7 CDJ66157.1 - 2.5 7.8 6.3 4.1 7.1 4.1 1.5 1 1 0 1 1 1 0 Serglycin RAP1 PF07218.6 CDJ66157.1 - 2.5 6.0 4.9 3.7 5.5 3.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Inositol_P PF00459.20 CDJ66158.1 - 1.2e-20 73.9 0.1 2e-20 73.2 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family SSP160 PF06933.6 CDJ66158.1 - 0.11 10.4 18.7 0.14 10.0 12.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RAP1 PF07218.6 CDJ66158.1 - 0.17 9.9 13.5 0.22 9.5 9.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Parvo_coat PF00740.13 CDJ66159.1 - 7.1 5.4 6.0 7.6 5.3 4.1 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 IMCp PF12314.3 CDJ66160.1 - 1.8e-08 34.3 52.3 0.0031 17.6 6.8 3.4 1 1 2 3 3 3 3 Inner membrane complex protein DUF1645 PF07816.6 CDJ66160.1 - 1.1 9.6 14.6 3.9 7.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Dehydrin PF00257.14 CDJ66160.1 - 1.4 9.2 11.4 1.1 9.5 2.0 2.5 2 0 0 2 2 2 0 Dehydrin DUF755 PF05501.6 CDJ66160.1 - 7.1 6.7 42.0 0.084 12.9 11.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF755) Med15 PF09606.5 CDJ66161.1 - 0.00055 18.2 22.0 0.00055 18.2 15.3 3.0 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4050 PF13259.1 CDJ66161.1 - 0.0011 18.8 1.2 0.15 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) BRF1 PF07741.8 CDJ66161.1 - 0.0076 16.4 0.3 0.0076 16.4 0.2 2.6 3 0 0 3 3 3 1 Brf1-like TBP-binding domain IncA PF04156.9 CDJ66161.1 - 0.016 14.8 0.6 0.016 14.8 0.4 3.0 3 0 0 3 3 3 0 IncA protein Dala_Dala_lig_N PF01820.16 CDJ66161.1 - 0.8 10.0 5.6 9.3 6.5 0.1 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Shadoo PF14999.1 CDJ66161.1 - 2.3 8.0 30.1 2.3 8.0 8.3 2.8 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Spt20 PF12090.3 CDJ66161.1 - 7.6 5.8 21.4 0.054 12.8 0.3 2.1 2 0 0 2 2 2 0 Spt20 family Endonuc_Holl PF10107.4 CDJ66161.1 - 8.3 6.0 14.0 6.6 6.3 3.5 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase PRP3 PF08572.5 CDJ66161.1 - 8.8 5.6 22.5 1.8 7.8 1.5 2.1 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) DUF4392 PF14336.1 CDJ66162.1 - 2.2e-22 79.1 0.0 1e-18 67.1 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4392) 7tm_7 PF08395.7 CDJ66162.1 - 0.17 10.9 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF1631 PF07793.6 CDJ66164.1 - 1.4 6.9 15.0 1.7 6.6 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PAP_central PF04928.12 CDJ66165.1 - 7.6e-83 277.2 0.0 1.2e-82 276.5 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CDJ66165.1 - 2.5e-21 75.8 0.0 2e-20 72.9 0.0 2.3 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CDJ66165.1 - 1.4e-06 28.5 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain SpoIISA_toxin PF14171.1 CDJ66166.1 - 0.45 9.7 1.9 0.62 9.2 1.3 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Ribosomal_60s PF00428.14 CDJ66166.1 - 0.87 10.0 14.0 1.2 9.5 6.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein OmpH PF03938.9 CDJ66166.1 - 1.3 8.9 33.8 1.6 8.6 23.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PAT1 PF09770.4 CDJ66166.1 - 4.6 5.3 30.9 4.7 5.3 21.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.4 CDJ66166.1 - 6.9 6.3 19.9 1.4 8.6 11.3 1.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA SR-25 PF10500.4 CDJ66167.1 - 0.32 10.4 49.1 0.76 9.2 9.9 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.8 CDJ66167.1 - 0.33 10.1 26.8 0.45 9.6 18.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2413 PF10310.4 CDJ66167.1 - 1.2 7.8 36.6 1.6 7.4 25.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PLRV_ORF5 PF01690.12 CDJ66167.1 - 4.2 6.4 23.4 5 6.1 16.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Macoilin PF09726.4 CDJ66167.1 - 4.5 5.4 26.9 5.4 5.1 18.7 1.0 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 CDJ66167.1 - 4.9 5.1 11.9 5 5.0 8.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Chorion_2 PF03964.10 CDJ66167.1 - 6.3 7.4 42.7 0.12 12.8 9.9 2.6 1 1 1 2 2 2 0 Chorion family 2 DNA_pol_viral_N PF00242.12 CDJ66167.1 - 8 5.3 31.9 10 5.0 22.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Opi1 PF08618.5 CDJ66167.1 - 9.6 5.0 34.6 12 4.6 24.0 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 HdeA PF06411.6 CDJ66168.1 - 0.75 9.7 8.6 1.6 8.7 5.9 1.6 1 0 0 1 1 1 0 HdeA/HdeB family SR-25 PF10500.4 CDJ66169.1 - 9.5e-05 21.9 10.7 9.5e-05 21.9 7.4 9.1 3 1 6 9 9 9 3 Nuclear RNA-splicing-associated protein zf-C2HC_2 PF13913.1 CDJ66169.1 - 0.0066 16.0 5.7 0.019 14.6 3.9 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type DUF2065 PF09838.4 CDJ66170.1 - 0.1 12.3 0.1 0.42 10.3 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) Las1 PF04031.8 CDJ66170.1 - 2.3 7.8 6.9 0.11 12.0 0.9 1.6 2 0 0 2 2 2 0 Las1-like Suf PF05843.9 CDJ66170.1 - 3.9 7.1 17.6 0.37 10.4 1.3 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Folate_carrier PF01770.13 CDJ66170.1 - 4.3 5.7 6.7 0.26 9.7 0.7 1.7 1 1 1 2 2 2 0 Reduced folate carrier Ribosomal_60s PF00428.14 CDJ66171.1 - 0.0051 17.1 5.3 0.0051 17.1 3.7 2.9 2 1 1 3 3 3 1 60s Acidic ribosomal protein Pkinase PF00069.20 CDJ66172.1 - 1e-42 146.1 13.3 2.2e-18 66.3 7.5 5.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ66172.1 - 2.2e-19 69.5 5.6 1.7e-14 53.4 0.2 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase UPF0564 PF10595.4 CDJ66172.1 - 0.0015 17.4 17.0 0.0015 17.4 11.8 3.2 3 0 0 3 3 3 1 Uncharacterised protein family UPF0564 SAPS PF04499.10 CDJ66172.1 - 7.7 5.0 22.9 0.011 14.4 2.4 2.6 2 1 1 3 3 3 0 SIT4 phosphatase-associated protein Presenilin PF01080.12 CDJ66174.1 - 0.14 10.9 0.4 0.17 10.6 0.3 1.1 1 0 0 1 1 1 0 Presenilin DUF1183 PF06682.7 CDJ66174.1 - 0.47 9.9 5.5 0.56 9.7 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RAP1 PF07218.6 CDJ66174.1 - 0.8 7.7 10.7 0.92 7.5 7.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF566 PF04484.7 CDJ66174.1 - 4.2 6.8 18.7 5.3 6.4 13.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF755 PF05501.6 CDJ66174.1 - 8.2 6.5 21.4 17 5.5 14.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CPSF73-100_C PF11718.3 CDJ66176.1 - 4.5e-05 22.9 0.0 4.5e-05 22.9 0.0 2.4 3 0 0 3 3 3 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Dimerisation PF08100.6 CDJ66178.1 - 0.093 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Plasmodium_Vir PF05795.6 CDJ66178.1 - 0.2 10.8 9.2 0.059 12.5 0.2 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ycf1 PF05758.7 CDJ66178.1 - 0.42 8.2 6.5 0.6 7.7 4.5 1.1 1 0 0 1 1 1 0 Ycf1 FimP PF09766.4 CDJ66178.1 - 0.45 9.5 23.4 0.25 10.3 10.1 2.1 2 0 0 2 2 2 0 Fms-interacting protein zf-DHHC PF01529.15 CDJ66178.1 - 0.54 9.6 1.9 0.85 8.9 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Casc1 PF12366.3 CDJ66178.1 - 0.9 8.9 9.7 0.083 12.3 2.3 2.0 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 DUF4557 PF15101.1 CDJ66178.1 - 0.95 9.2 23.8 1.8 8.3 9.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Peptidase_S49_N PF08496.5 CDJ66178.1 - 1.1 9.0 13.4 1 9.1 4.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal IncA PF04156.9 CDJ66178.1 - 1.5 8.4 27.2 3.2 7.3 1.6 2.3 2 0 0 2 2 2 0 IncA protein SAPS PF04499.10 CDJ66178.1 - 6.1 5.3 13.5 0.82 8.2 5.9 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Spt20 PF12090.3 CDJ66178.1 - 8.4 5.7 15.9 4 6.7 5.3 2.3 2 0 0 2 2 2 0 Spt20 family HTH_32 PF13565.1 CDJ66178.1 - 10 7.0 7.8 0.65 10.8 0.8 2.6 2 1 0 2 2 2 0 Homeodomain-like domain OmpH PF03938.9 CDJ66179.1 - 1.4 8.8 39.0 1.6 8.6 27.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Arch_fla_DE PF04659.8 CDJ66182.1 - 0.039 13.7 0.0 0.089 12.6 0.0 1.5 2 0 0 2 2 2 0 Archaeal flagella protein Histone PF00125.19 CDJ66183.1 - 6.4e-05 23.0 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.19 CDJ66184.1 - 9.3e-26 89.7 0.0 1.2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDJ66184.1 - 7.4e-05 22.7 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ras PF00071.17 CDJ66187.1 - 1.1e-25 89.9 0.0 1.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ66187.1 - 0.00028 21.3 0.7 0.00044 20.7 0.0 1.7 2 1 0 2 2 2 1 Miro-like protein DUF2867 PF11066.3 CDJ66187.1 - 0.15 11.7 0.2 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2867) Med15 PF09606.5 CDJ66188.1 - 0.013 13.7 82.9 0.0065 14.7 7.6 3.0 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDJ66189.1 - 0.033 13.9 0.7 0.037 13.7 0.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FTCD_C PF04961.7 CDJ66189.1 - 0.32 10.4 3.8 0.51 9.7 2.6 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF4630 PF15443.1 CDJ66189.1 - 0.37 10.5 5.1 0.43 10.3 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Ribosomal_60s PF00428.14 CDJ66189.1 - 3.1 8.2 8.1 4.3 7.8 5.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein TSSC4 PF15264.1 CDJ66190.1 - 0.0014 19.0 0.2 0.0014 19.0 0.1 3.2 3 0 0 3 3 3 1 Tumour suppressing sub-chromosomal transferable candidate 4 AAA_23 PF13476.1 CDJ66190.1 - 0.021 15.1 0.1 0.021 15.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain Gpi1 PF05024.10 CDJ66191.1 - 4e-25 88.5 5.4 6.4e-25 87.9 3.7 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF566 PF04484.7 CDJ66191.1 - 0.78 9.2 12.6 0.026 14.0 3.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF566) SR-25 PF10500.4 CDJ66191.1 - 1.3 8.4 24.9 0.18 11.2 5.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1645 PF07816.6 CDJ66191.1 - 8.3 6.8 20.8 0.34 11.3 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) DUF3712 PF12505.3 CDJ66192.1 - 0.0013 18.7 0.0 0.47 10.4 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) Med15 PF09606.5 CDJ66192.1 - 0.0032 15.7 0.4 0.0032 15.7 0.3 4.8 5 0 0 5 5 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal SAPS PF04499.10 CDJ66192.1 - 0.01 14.4 10.2 0.018 13.6 7.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDJ66192.1 - 0.12 10.0 17.0 0.2 9.3 11.8 1.2 1 0 0 1 1 1 0 Ycf1 TT_ORF1 PF02956.9 CDJ66192.1 - 0.18 10.1 9.9 0.34 9.2 6.9 1.3 1 0 0 1 1 1 0 TT viral orf 1 Tim54 PF11711.3 CDJ66192.1 - 0.21 10.1 11.2 0.41 9.1 7.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Otopetrin PF03189.8 CDJ66192.1 - 0.37 9.7 0.2 0.54 9.1 0.2 1.2 1 0 0 1 1 1 0 Otopetrin TFIIA PF03153.8 CDJ66192.1 - 0.57 10.0 51.6 0.081 12.8 23.0 3.3 4 0 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.12 CDJ66192.1 - 0.58 9.9 23.2 0.023 14.5 10.4 2.4 3 0 0 3 3 2 0 DDHD domain Zip PF02535.17 CDJ66192.1 - 0.64 8.9 6.0 1.4 7.8 4.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.1 CDJ66192.1 - 0.85 8.0 21.4 7.2 5.0 13.7 2.1 2 0 0 2 2 2 0 Raftlin LMBR1 PF04791.11 CDJ66192.1 - 1.4 7.4 4.7 2.6 6.5 3.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SPX PF03105.14 CDJ66192.1 - 1.6 8.4 18.0 0.78 9.4 9.7 2.2 3 0 0 3 3 3 0 SPX domain Presenilin PF01080.12 CDJ66192.1 - 1.9 7.2 14.3 3.7 6.2 9.9 1.4 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.1 CDJ66192.1 - 2.3 7.6 39.2 0.056 12.8 19.8 2.3 2 0 0 2 2 2 0 Spore coat protein CotO CDC45 PF02724.9 CDJ66192.1 - 2.6 5.9 23.0 4.4 5.2 14.4 2.0 2 0 0 2 2 2 0 CDC45-like protein SAGA-Tad1 PF12767.2 CDJ66192.1 - 2.8 7.5 28.8 2.7 7.6 14.5 2.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1510 PF07423.6 CDJ66192.1 - 9 5.5 32.6 0.13 11.6 16.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 CDJ66192.1 - 9.9 4.8 25.4 17 4.1 16.9 1.7 2 0 0 2 2 2 0 Floricaula / Leafy protein IncA PF04156.9 CDJ66194.1 - 0.012 15.2 7.1 0.012 15.2 4.9 2.8 4 0 0 4 4 4 0 IncA protein CAF-1_p150 PF11600.3 CDJ66194.1 - 1.5 8.1 31.7 0.32 10.3 13.7 2.5 1 1 2 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDJ66195.1 - 0.00052 18.4 25.3 0.00052 18.4 17.5 2.3 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDJ66195.1 - 1.6 6.3 16.0 2.1 5.8 11.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 CDJ66195.1 - 2 7.7 18.3 3.4 6.9 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dicty_REP PF05086.7 CDJ66195.1 - 2.9 5.5 8.3 3.6 5.2 5.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SR-25 PF10500.4 CDJ66195.1 - 3.3 7.1 27.1 0.72 9.2 8.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.1 CDJ66195.1 - 3.7 6.4 25.8 0.21 10.4 7.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.11 CDJ66195.1 - 6.2 6.6 9.7 14 5.5 6.7 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 CDJ66195.1 - 6.6 4.6 20.0 9.6 4.0 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.7 CDJ66195.1 - 7.4 5.0 20.6 12 4.4 14.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) XAP5 PF04921.9 CDJ66195.1 - 7.9 5.9 14.9 11 5.4 10.3 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DDHD PF02862.12 CDJ66195.1 - 8.3 6.1 13.5 18 4.9 9.3 1.6 1 0 0 1 1 1 0 DDHD domain zf-C3HC4_2 PF13923.1 CDJ66196.1 - 0.00011 22.1 0.9 0.00025 20.9 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDJ66196.1 - 0.0016 18.0 0.3 0.0043 16.6 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ66196.1 - 0.0034 17.1 0.3 0.0071 16.1 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CDJ66196.1 - 0.0043 16.7 0.2 0.0088 15.7 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CDJ66196.1 - 0.015 14.9 0.2 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDJ66196.1 - 0.056 13.3 0.4 0.16 11.8 0.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3984 PF13136.1 CDJ66197.1 - 0.46 9.6 12.6 0.57 9.3 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Tho2 PF11262.3 CDJ66197.1 - 8.3 5.3 9.2 9.9 5.1 6.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 UCH PF00443.24 CDJ66199.1 - 7.1e-37 126.9 0.0 9.8e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CDJ66199.1 - 2e-13 50.1 4.7 3.6e-13 49.3 3.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein AF-4 PF05110.8 CDJ66199.1 - 0.0015 16.5 18.4 0.0021 16.0 12.7 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DUF508 PF04370.7 CDJ66199.1 - 0.048 13.2 4.0 0.11 12.1 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF508) SR-25 PF10500.4 CDJ66199.1 - 0.42 10.0 21.0 0.76 9.1 14.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Abhydrolase_5 PF12695.2 CDJ66200.1 - 0.00019 21.2 0.3 0.00096 18.9 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Med15 PF09606.5 CDJ66200.1 - 0.95 7.5 48.7 1.9 6.5 33.8 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AvrE PF11725.3 CDJ66200.1 - 3.5 4.5 15.3 4.9 4.0 10.6 1.1 1 0 0 1 1 1 0 Pathogenicity factor Baculo_PP31 PF05311.6 CDJ66200.1 - 9.8 5.3 13.8 0.34 10.1 3.7 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) ORC2 PF04084.9 CDJ66201.1 - 2.9e-30 105.2 0.0 1.6e-17 63.3 0.0 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 2 DUF2151 PF10221.4 CDJ66201.1 - 0.029 12.5 0.8 0.05 11.7 0.6 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Tom37_C PF11801.3 CDJ66201.1 - 5.9 6.7 7.5 11 5.8 2.4 2.5 2 0 0 2 2 2 0 Tom37 C-terminal domain adh_short PF00106.20 CDJ66202.1 - 5.4e-11 42.6 1.1 6.8e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CDJ66202.1 - 0.00013 21.7 2.1 0.00027 20.6 0.0 2.3 3 0 0 3 3 3 1 KR domain Kelch_3 PF13415.1 CDJ66203.1 - 7.5e-21 73.7 6.3 4.5e-06 26.6 0.0 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CDJ66203.1 - 7e-19 67.3 14.3 1.5e-05 24.7 0.0 4.4 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CDJ66203.1 - 1.1e-17 63.2 4.2 6.5e-05 22.9 0.0 4.6 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CDJ66203.1 - 1e-16 60.2 0.9 3.7e-06 26.3 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 CDJ66203.1 - 4.3e-16 58.4 6.6 0.0042 16.9 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 CDJ66203.1 - 8.6e-12 44.3 9.3 0.018 14.7 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Fzo_mitofusin PF04799.8 CDJ66203.1 - 0.14 11.5 0.1 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 fzo-like conserved region Cep57_CLD_2 PF14197.1 CDJ66203.1 - 0.4 10.6 5.0 3 7.8 1.6 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 IncA PF04156.9 CDJ66203.1 - 4.1 6.9 7.8 5.1 6.6 1.8 2.1 2 0 0 2 2 2 0 IncA protein TFIIS_C PF01096.13 CDJ66204.1 - 1.5e-14 53.3 3.7 1.5e-14 53.3 2.5 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DNA_RNApol_7kD PF03604.8 CDJ66204.1 - 2 7.9 18.7 0.86 9.1 0.8 4.4 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 CDJ66204.1 - 4.1 7.4 13.6 32 4.5 0.2 4.5 3 1 0 4 4 4 0 Zinc ribbon domain DUF2757 PF10955.3 CDJ66204.1 - 4.7 7.4 11.4 0.69 10.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) Exo_endo_phos PF03372.18 CDJ66205.1 - 8.4e-17 61.9 0.1 1.2e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1192 PF06698.6 CDJ66206.1 - 0.35 10.7 1.7 0.42 10.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ABC_ATPase PF09818.4 CDJ66207.1 - 4.1e-173 576.0 0.0 5.5e-173 575.6 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 CDJ66207.1 - 0.022 15.0 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CDJ66207.1 - 0.16 11.5 0.1 0.43 10.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNase_HII PF01351.13 CDJ66208.1 - 0.15 11.6 0.1 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease HII Ribosomal_60s PF00428.14 CDJ66208.1 - 2.4 8.6 5.8 2.3 8.6 2.6 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 CDJ66209.1 - 0.00062 18.7 27.9 0.00062 18.7 19.3 3.2 2 1 1 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor DUF2052 PF09747.4 CDJ66209.1 - 5.5 6.8 28.5 2.5 8.0 8.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Band_3_cyto PF07565.8 CDJ66209.1 - 6 6.2 27.3 0.45 9.9 5.8 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain VIT1 PF01988.14 CDJ66210.1 - 0.006 16.1 2.3 0.006 16.1 1.6 2.3 2 0 0 2 2 2 1 VIT family Ycf1 PF05758.7 CDJ66210.1 - 6.5 4.3 16.6 9.5 3.7 11.5 1.2 1 0 0 1 1 1 0 Ycf1 SR-25 PF10500.4 CDJ66211.1 - 0.051 13.0 23.2 0.085 12.3 16.0 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CDJ66211.1 - 0.093 11.0 12.8 0.11 10.8 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CAF-1_p150 PF11600.3 CDJ66211.1 - 0.21 10.9 9.3 0.28 10.5 6.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1183 PF06682.7 CDJ66211.1 - 0.5 9.9 6.7 0.63 9.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Apt1 PF10351.4 CDJ66211.1 - 1.8 7.3 6.7 2.2 7.0 4.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2217 PF10265.4 CDJ66211.1 - 5.3 5.6 8.3 5.6 5.6 5.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) WBS_methylT PF12589.3 CDJ66212.1 - 0.073 13.5 8.9 0.12 12.9 6.1 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome SR-25 PF10500.4 CDJ66213.1 - 3e-05 23.6 34.4 0.00089 18.7 4.3 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Claudin_2 PF13903.1 CDJ66213.1 - 0.11 12.1 3.0 0.18 11.5 2.1 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Cellulose_synt PF03552.9 CDJ66213.1 - 1 7.5 3.3 1.5 7.0 2.3 1.1 1 0 0 1 1 1 0 Cellulose synthase Suf PF05843.9 CDJ66213.1 - 8.5 6.0 11.5 0.18 11.4 1.6 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Suf PF05843.9 CDJ66214.1 - 7.8e-05 22.5 11.1 0.00012 21.9 7.7 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Rpr2 PF04032.11 CDJ66214.1 - 0.00063 19.5 32.1 0.00063 19.5 22.2 3.7 2 2 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain AAA_23 PF13476.1 CDJ66214.1 - 0.0016 18.7 1.1 0.0021 18.4 0.7 1.2 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 CDJ66214.1 - 0.0037 16.8 16.3 0.0037 16.8 11.3 2.8 3 0 0 3 3 3 1 IncA protein DUF605 PF04652.11 CDJ66214.1 - 2 7.6 25.4 0.095 12.0 13.3 1.7 2 0 0 2 2 2 0 Vta1 like EIIBC-GUT_N PF03612.9 CDJ66214.1 - 3.3 7.3 6.6 7 6.2 4.6 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PH_4 PF15404.1 CDJ66214.1 - 6.7 6.2 12.5 0.19 11.2 4.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Med15 PF09606.5 CDJ66215.1 - 0.034 12.3 9.8 0.037 12.2 6.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Flavi_NS4A PF01350.12 CDJ66215.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Sporozoite_P67 PF05642.6 CDJ66215.1 - 0.15 9.9 2.2 0.16 9.7 1.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3357 PF11837.3 CDJ66215.1 - 1.3 8.9 6.9 4.9 7.0 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Sec63 PF02889.11 CDJ66216.1 - 3e-14 52.9 0.1 3.2e-14 52.8 0.1 1.0 1 0 0 1 1 1 1 Sec63 Brl domain T4_baseplate PF12322.3 CDJ66216.1 - 0.0044 16.2 0.0 0.0094 15.2 0.0 1.5 1 0 0 1 1 1 1 T4 bacteriophage base plate protein MT-A70 PF05063.9 CDJ66218.1 - 2.9e-24 85.5 1.2 5.9e-11 42.2 0.0 3.6 2 1 1 3 3 3 3 MT-A70 Methyltransf_26 PF13659.1 CDJ66218.1 - 0.12 12.3 0.1 0.71 9.9 0.0 2.0 1 1 0 2 2 2 0 Methyltransferase domain Cyclin PF08613.6 CDJ66219.1 - 2.7e-28 99.2 0.0 4.1e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CDJ66219.1 - 9.3e-12 44.6 0.2 1.4e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chorion_2 PF03964.10 CDJ66220.1 - 0.6 10.6 5.7 0.79 10.2 2.9 1.9 2 0 0 2 2 2 0 Chorion family 2 Methyltransf_16 PF10294.4 CDJ66221.1 - 0.0043 16.5 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF2183 PF09949.4 CDJ66222.1 - 0.022 14.6 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) HECT PF00632.20 CDJ66225.1 - 4.8e-36 124.5 0.2 1.2e-35 123.2 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.2 CDJ66225.1 - 3.1e-14 53.0 0.0 4.5e-08 33.3 0.0 2.9 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ66225.1 - 2.8e-11 42.6 0.2 0.016 15.0 0.0 4.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CDJ66225.1 - 3.7e-09 36.5 2.9 0.025 14.8 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDJ66225.1 - 9.4e-07 29.1 0.1 0.098 13.1 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ66225.1 - 0.00084 19.3 0.0 3.7 8.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Mem_trans PF03547.13 CDJ66225.1 - 6.4 4.9 1.8 5.4 5.1 0.0 1.7 2 0 0 2 2 2 0 Membrane transport protein DUF2217 PF10265.4 CDJ66225.1 - 6.4 5.4 4.6 16 4.1 3.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DXPR_C PF13288.1 CDJ66227.1 - 2.8e-29 101.5 1.3 1.5e-21 76.6 0.1 2.2 1 1 1 2 2 2 2 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.7 CDJ66227.1 - 1.6e-09 37.5 0.3 3.9e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal DXP_reductoisom PF02670.11 CDJ66228.1 - 4e-33 114.7 0.1 4e-33 114.7 0.0 3.9 4 1 0 4 4 4 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.7 CDJ66228.1 - 2.1e-13 49.9 0.0 5.7e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal PAT1 PF09770.4 CDJ66228.1 - 0.49 8.5 37.5 0.19 9.9 20.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PMI_typeI PF01238.16 CDJ66228.1 - 0.6 9.0 8.3 0.88 8.4 5.8 1.2 1 0 0 1 1 1 0 Phosphomannose isomerase type I GFO_IDH_MocA PF01408.17 CDJ66228.1 - 0.85 10.1 0.0 0.85 10.1 0.0 3.4 3 2 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Not1 PF04054.10 CDJ66229.1 - 2.6e-94 316.1 1.0 6.1e-57 193.2 0.3 3.0 3 0 0 3 3 3 2 CCR4-Not complex component, Not1 CD20 PF04103.10 CDJ66230.1 - 0.00066 19.6 13.0 0.0017 18.2 1.2 3.3 2 1 0 3 3 3 2 CD20-like family DUF4131 PF13567.1 CDJ66230.1 - 0.0024 17.2 2.0 0.051 12.9 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) SHR3_chaperone PF08229.6 CDJ66230.1 - 2.5 6.9 13.9 1.5 7.7 1.3 2.7 2 0 0 2 2 2 0 ER membrane protein SH3 Folate_carrier PF01770.13 CDJ66230.1 - 3.7 5.9 6.9 0.79 8.1 0.6 2.2 2 0 0 2 2 2 0 Reduced folate carrier SR-25 PF10500.4 CDJ66232.1 - 0.018 14.5 14.8 0.018 14.5 10.3 4.2 4 1 0 4 4 4 0 Nuclear RNA-splicing-associated protein DNA_pol_B_exo1 PF03104.14 CDJ66234.1 - 5.9e-37 127.2 0.0 1.4e-36 126.0 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.1 CDJ66234.1 - 6e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 CDJ66234.1 - 9.1e-05 22.0 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF3115 PF11312.3 CDJ66234.1 - 0.14 11.0 0.2 0.22 10.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3115) FCP1_C PF09309.5 CDJ66236.1 - 0.21 10.8 8.9 0.22 10.7 6.2 1.0 1 0 0 1 1 1 0 FCP1, C-terminal Spt20 PF12090.3 CDJ66236.1 - 0.3 10.4 8.5 0.29 10.4 5.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF4175 PF13779.1 CDJ66236.1 - 0.69 7.5 17.4 0.67 7.5 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PSK PF06404.7 CDJ66236.1 - 0.71 10.6 4.1 0.78 10.5 2.8 1.2 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) Activator_LAG-3 PF11498.3 CDJ66236.1 - 0.76 8.4 21.6 0.72 8.5 15.0 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 LIM_bind PF01803.11 CDJ66236.1 - 0.87 8.6 8.8 0.93 8.5 6.1 1.0 1 0 0 1 1 1 0 LIM-domain binding protein Pex14_N PF04695.8 CDJ66236.1 - 1.4 8.9 13.2 1.6 8.8 9.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Trypan_glycop_C PF10659.4 CDJ66236.1 - 1.6 9.0 6.3 2 8.7 4.3 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain FimP PF09766.4 CDJ66236.1 - 1.7 7.6 13.9 1.9 7.4 9.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDJ66236.1 - 2.3 7.9 11.7 2.2 7.9 8.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ATAD4 PF15321.1 CDJ66236.1 - 2.4 9.2 5.3 2.5 9.1 3.7 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 RAB3GAP2_N PF14655.1 CDJ66236.1 - 2.6 6.9 8.0 2.5 7.0 5.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4557 PF15101.1 CDJ66236.1 - 2.8 7.7 10.9 2.7 7.8 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) BRF1 PF07741.8 CDJ66236.1 - 3.1 8.0 7.8 3.6 7.8 5.4 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF3408 PF11888.3 CDJ66236.1 - 3.5 7.5 6.5 3.4 7.5 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SIT PF15330.1 CDJ66236.1 - 3.6 7.7 8.4 3.8 7.6 5.8 1.1 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3708 PF12501.3 CDJ66236.1 - 4 7.2 6.4 4.2 7.1 4.5 1.0 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Kei1 PF08552.6 CDJ66236.1 - 4.3 6.9 5.7 4.5 6.8 4.0 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Baculo_PP31 PF05311.6 CDJ66236.1 - 4.7 6.3 6.8 4.9 6.3 4.7 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Ctr PF04145.10 CDJ66236.1 - 5.4 7.0 5.9 6 6.9 4.1 1.0 1 0 0 1 1 1 0 Ctr copper transporter family DUF3464 PF11947.3 CDJ66236.1 - 5.7 6.3 6.5 6.1 6.2 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RR_TM4-6 PF06459.7 CDJ66236.1 - 7.1 6.4 8.3 6.8 6.4 5.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.1 CDJ66236.1 - 7.3 6.7 6.6 7.4 6.7 4.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PAT1 PF09770.4 CDJ66236.1 - 7.6 4.6 22.2 7.1 4.7 15.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ66236.1 - 7.7 6.2 16.4 8.1 6.2 11.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF775 PF05603.7 CDJ66236.1 - 7.9 5.9 8.6 8.3 5.8 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ndc1_Nup PF09531.5 CDJ66236.1 - 8.8 4.6 6.3 8.9 4.5 4.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIH1 PF08190.7 CDJ66236.1 - 9.3 5.5 12.2 10 5.4 8.4 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Bac_GDH PF05088.7 CDJ66237.1 - 6.4e-10 37.1 0.0 6.4e-10 37.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 CDJ66237.1 - 9.4e-05 22.0 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ribosomal_60s PF00428.14 CDJ66237.1 - 0.019 15.3 2.2 0.057 13.8 1.5 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.3 CDJ66237.1 - 0.069 12.4 5.0 0.12 11.7 3.5 1.4 1 0 0 1 1 1 0 Spt20 family Peptidase_U57 PF05582.7 CDJ66237.1 - 0.093 11.6 4.9 0.17 10.8 3.4 1.4 1 0 0 1 1 1 0 YabG peptidase U57 BRF1 PF07741.8 CDJ66237.1 - 0.13 12.4 4.2 0.25 11.6 2.9 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FimP PF09766.4 CDJ66237.1 - 0.18 10.8 16.2 0.012 14.6 7.3 1.9 2 0 0 2 2 2 0 Fms-interacting protein RED_N PF07808.8 CDJ66237.1 - 0.58 9.3 9.7 0.81 8.8 6.7 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Suf PF05843.9 CDJ66237.1 - 0.65 9.6 6.8 1 9.0 4.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDJ66237.1 - 1.3 9.0 10.2 1.7 8.6 6.4 1.7 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.7 CDJ66237.1 - 2.5 6.6 9.8 3.1 6.3 6.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.5 CDJ66237.1 - 2.5 6.4 4.7 3.3 6.0 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pol_alpha_B_N PF08418.5 CDJ66237.1 - 4.1 6.8 9.6 6.6 6.1 6.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2435 PF10363.4 CDJ66239.1 - 0.0048 16.7 0.6 0.011 15.6 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) RTTN_N PF14726.1 CDJ66239.1 - 0.013 16.1 2.0 0.62 10.6 0.4 2.2 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Ribosomal_60s PF00428.14 CDJ66239.1 - 0.021 15.1 3.8 0.021 15.1 2.6 3.8 3 1 0 3 3 3 0 60s Acidic ribosomal protein HEAT PF02985.17 CDJ66239.1 - 0.037 14.1 0.1 0.2 11.8 0.1 2.4 1 0 0 1 1 1 0 HEAT repeat PALP PF00291.20 CDJ66239.1 - 0.42 9.7 8.5 0.27 10.3 3.0 2.2 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Ribosomal_60s PF00428.14 CDJ66240.1 - 0.043 14.2 11.7 0.39 11.1 2.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein LZ_Tnp_IS66 PF13007.2 CDJ66240.1 - 0.13 12.9 8.1 0.68 10.6 0.2 2.2 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain IQ PF00612.22 CDJ66241.1 - 1.2e-05 24.5 31.4 0.0083 15.6 0.7 4.4 4 0 0 4 4 4 3 IQ calmodulin-binding motif NUDE_C PF04880.8 CDJ66242.1 - 0.55 10.5 4.1 0.72 10.2 2.8 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ketoacyl-synt PF00109.21 CDJ66243.1 - 1e-116 388.8 5.8 1e-70 238.1 0.0 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CDJ66243.1 - 5.6e-59 197.2 8.7 4.5e-38 129.7 0.3 3.2 3 0 0 3 3 3 2 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 CDJ66243.1 - 3.2e-51 173.5 0.0 9.5e-51 172.0 0.0 1.9 1 1 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 CDJ66243.1 - 1.6e-48 165.7 1.9 4.1e-48 164.3 1.3 1.7 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 CDJ66243.1 - 3.1e-41 141.0 0.1 2.2e-40 138.3 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 CDJ66243.1 - 8.8e-36 123.5 0.0 2.1e-35 122.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 CDJ66243.1 - 2.6e-13 50.0 0.4 5.4e-13 49.0 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 CDJ66243.1 - 0.0016 17.5 2.0 0.17 10.8 0.1 2.3 2 0 0 2 2 2 2 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CDJ66243.1 - 0.27 10.8 6.2 0.16 11.6 0.4 2.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2341 PF10102.4 CDJ66243.1 - 0.31 11.1 0.0 0.68 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) DUF4426 PF14467.1 CDJ66243.1 - 0.36 10.6 0.0 46 3.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) Zw10 PF06248.8 CDJ66243.1 - 1.7 6.6 0.0 2.8 5.9 0.0 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 AAA_23 PF13476.1 CDJ66244.1 - 2.3 8.4 10.0 6.3 7.0 7.0 1.6 1 1 0 1 1 1 0 AAA domain DUF4140 PF13600.1 CDJ66244.1 - 2.5 8.5 0.0 2.5 8.5 0.0 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) APC_CDC26 PF10471.4 CDJ66244.1 - 7.4 7.3 31.7 2.5 8.8 6.6 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF755 PF05501.6 CDJ66245.1 - 1.3 9.1 26.7 0.063 13.3 14.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) AAA_13 PF13166.1 CDJ66245.1 - 9.4 4.5 14.4 8.3 4.7 9.4 1.3 1 1 0 1 1 1 0 AAA domain VPS11_C PF12451.3 CDJ66246.1 - 0.054 13.3 0.6 0.054 13.3 0.4 3.4 4 0 0 4 4 4 0 Vacuolar protein sorting protein 11 C terminal DUF2003 PF09404.5 CDJ66246.1 - 0.067 11.5 1.9 0.11 10.8 1.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF2003) Med15 PF09606.5 CDJ66246.1 - 3 5.9 64.7 1.4 7.0 4.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cas_Csy4 PF09618.5 CDJ66247.1 - 0.062 13.1 0.1 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) BMF PF15185.1 CDJ66247.1 - 0.58 9.4 5.0 0.67 9.2 3.0 1.5 1 1 0 1 1 1 0 Bcl-2-modifying factor, apoptosis PAT1 PF09770.4 CDJ66247.1 - 5.9 4.9 19.0 6.2 4.9 13.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ66247.1 - 9.6 5.9 10.5 11 5.8 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.6 CDJ66248.1 - 0.00016 21.6 13.1 0.00024 21.1 9.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Dehydrin PF00257.14 CDJ66248.1 - 0.0016 18.8 2.4 0.0022 18.3 1.7 1.3 1 0 0 1 1 1 1 Dehydrin DUF1645 PF07816.6 CDJ66248.1 - 0.0026 18.2 1.9 0.0031 18.0 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) CDK2AP PF09806.4 CDJ66248.1 - 0.0069 16.6 3.6 0.008 16.4 2.5 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Med15 PF09606.5 CDJ66248.1 - 0.033 12.4 8.7 0.032 12.4 6.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Vasculin PF15337.1 CDJ66248.1 - 0.062 13.7 1.6 0.082 13.3 1.1 1.2 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Pex16 PF08610.5 CDJ66248.1 - 0.1 11.5 1.2 0.11 11.4 0.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FCP1_C PF09309.5 CDJ66248.1 - 0.12 11.6 2.7 0.16 11.2 1.9 1.1 1 0 0 1 1 1 0 FCP1, C-terminal MACPF PF01823.14 CDJ66248.1 - 0.15 11.7 2.0 0.18 11.4 1.4 1.0 1 0 0 1 1 1 0 MAC/Perforin domain BAF1_ABF1 PF04684.8 CDJ66248.1 - 0.2 10.4 6.6 0.18 10.6 4.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CDJ66248.1 - 0.22 10.8 1.9 0.23 10.7 1.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF2574 PF10836.3 CDJ66248.1 - 0.42 10.3 2.0 0.64 9.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) DUF4175 PF13779.1 CDJ66248.1 - 0.46 8.1 7.8 0.44 8.2 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) APC_CDC26 PF10471.4 CDJ66248.1 - 9 7.1 15.1 18 6.1 10.5 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 RVT_1 PF00078.22 CDJ66249.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2029 PF09594.5 CDJ66251.1 - 0.98 8.8 21.3 2 7.8 8.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) Phostensin PF13914.1 CDJ66251.1 - 1.2 9.2 10.6 0.23 11.5 0.2 2.6 2 1 1 3 3 3 0 Phostensin PP1-binding and SH3-binding region LCE PF14672.1 CDJ66251.1 - 2.1 8.9 17.0 1.2 9.7 2.0 3.2 2 2 2 4 4 4 0 Late cornified envelope Pep3_Vps18 PF05131.9 CDJ66253.1 - 3.7e-14 52.3 0.0 1.6e-13 50.3 0.0 2.0 1 1 0 1 1 1 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 CDJ66253.1 - 2.2e-05 24.5 2.7 5.4e-05 23.3 1.9 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 CDJ66253.1 - 0.0055 16.3 0.0 0.037 13.6 0.0 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS DUF607 PF04678.8 CDJ66253.1 - 0.087 12.7 0.1 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 WD40 PF00400.27 CDJ66255.1 - 9.2e-07 28.5 0.7 4.1e-05 23.3 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat SR-25 PF10500.4 CDJ66255.1 - 0.0011 18.4 3.1 0.0019 17.7 2.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein OmpH PF03938.9 CDJ66255.1 - 0.0043 17.0 15.5 0.038 13.9 6.7 2.2 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) SGT1 PF07093.6 CDJ66255.1 - 0.013 13.9 2.9 0.015 13.6 2.0 1.0 1 0 0 1 1 1 0 SGT1 protein BNIP3 PF06553.7 CDJ66255.1 - 0.14 11.4 10.4 0.23 10.8 7.2 1.2 1 0 0 1 1 1 0 BNIP3 DUF2161 PF09929.4 CDJ66255.1 - 0.95 9.3 4.6 1.6 8.6 0.4 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2161) ATP-synt_C PF00137.16 CDJ66255.1 - 1.3 8.9 6.4 12 5.8 0.4 2.5 2 0 0 2 2 2 0 ATP synthase subunit C NTP_transf_3 PF12804.2 CDJ66255.1 - 1.4 9.0 5.2 14 5.7 0.2 2.5 1 1 0 2 2 2 0 MobA-like NTP transferase domain FLO_LFY PF01698.11 CDJ66255.1 - 2.7 6.7 4.9 4 6.1 3.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PPP4R2 PF09184.6 CDJ66255.1 - 4.1 6.8 13.6 6 6.3 9.4 1.1 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.7 CDJ66255.1 - 5 6.7 13.6 7.5 6.1 9.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Na_trans_assoc PF06512.8 CDJ66255.1 - 9.6 6.0 10.2 15 5.4 7.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2431 PF10354.4 CDJ66257.1 - 0.00088 19.2 0.0 0.00088 19.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PP_kinase_C PF13090.1 CDJ66257.1 - 0.017 13.7 0.0 0.02 13.4 0.0 1.0 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain Peptidase_C48 PF02902.14 CDJ66258.1 - 2.5e-23 82.8 0.0 6.9e-23 81.3 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Activator_LAG-3 PF11498.3 CDJ66258.1 - 4 6.0 69.0 0.12 11.1 10.2 3.4 3 0 0 3 3 3 0 Transcriptional activator LAG-3 Na_trans_assoc PF06512.8 CDJ66259.1 - 0.027 14.4 8.4 0.043 13.7 5.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Macoilin PF09726.4 CDJ66259.1 - 0.24 9.6 28.7 0.39 8.9 19.8 1.4 1 1 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 CDJ66259.1 - 0.45 8.7 21.5 0.52 8.4 14.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDJ66259.1 - 2.7 7.6 7.7 1.2 8.8 3.3 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DNA_pol_viral_N PF00242.12 CDJ66259.1 - 9 5.2 22.3 14 4.5 15.5 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain NUC130_3NT PF08158.7 CDJ66260.1 - 0.028 14.6 1.8 1.1 9.6 0.1 3.3 2 0 0 2 2 2 0 NUC130/3NT domain BRCA2 PF00634.13 CDJ66263.1 - 6.8e-30 101.9 0.0 5.7e-05 22.2 0.0 6.4 6 0 0 6 6 6 6 BRCA2 repeat Trehalase_Ca-bi PF07492.6 CDJ66263.1 - 0.2 11.0 24.1 9.9 5.5 0.1 6.3 6 0 0 6 6 6 0 Neutral trehalase Ca2+ binding domain KH_1 PF00013.24 CDJ66264.1 - 2.6e-09 36.5 0.0 8e-07 28.6 0.0 2.8 3 1 0 3 3 3 2 KH domain KH_3 PF13014.1 CDJ66264.1 - 4.3e-08 32.6 1.4 5.7e-06 25.8 0.2 2.9 4 0 0 4 4 4 2 KH domain Surface_antigen PF11054.3 CDJ66267.1 - 5.9e-103 343.6 3.3 6.7e-103 343.5 2.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3439 PF11921.3 CDJ66267.1 - 0.018 14.8 2.4 0.02 14.6 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Surface_antigen PF11054.3 CDJ66268.1 - 5.5e-107 356.8 2.0 6.3e-107 356.7 1.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Peptidase_U57 PF05582.7 CDJ66269.1 - 0.019 13.9 4.1 0.051 12.5 2.9 1.8 1 0 0 1 1 1 0 YabG peptidase U57 PIN PF01850.16 CDJ66269.1 - 0.16 12.3 0.9 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 PIN domain PAF-AH_p_II PF03403.8 CDJ66269.1 - 4.7 5.3 9.5 7.5 4.7 6.6 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Alb1 PF09135.6 CDJ66269.1 - 6.3 7.4 9.8 0.48 11.0 2.8 2.1 2 0 0 2 2 2 0 Alb1 Ribosomal_60s PF00428.14 CDJ66270.1 - 0.13 12.6 9.9 0.093 13.1 4.4 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Metal_resist PF13801.1 CDJ66271.1 - 0.018 14.9 1.8 0.018 14.9 1.2 2.9 3 0 0 3 3 3 0 Heavy-metal resistance MAP65_ASE1 PF03999.7 CDJ66272.1 - 0.041 12.4 22.1 0.052 12.1 15.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF812 PF05667.6 CDJ66272.1 - 0.13 10.7 18.7 0.15 10.5 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2413 PF10310.4 CDJ66272.1 - 0.27 10.0 25.0 0.28 9.9 17.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SR-25 PF10500.4 CDJ66272.1 - 0.5 9.7 32.2 1.2 8.5 20.8 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Mucin PF01456.12 CDJ66272.1 - 0.78 9.5 11.3 1.1 9.0 7.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CDC27 PF09507.5 CDJ66272.1 - 0.92 8.6 23.2 1.1 8.4 16.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MTBP_C PF14920.1 CDJ66272.1 - 2 7.8 21.1 2.5 7.5 14.7 1.1 1 0 0 1 1 1 0 MDM2-binding DUF1675 PF07897.6 CDJ66272.1 - 4.9 6.9 20.9 6.2 6.6 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PAT1 PF09770.4 CDJ66272.1 - 5.6 5.0 36.7 6.7 4.8 25.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4603 PF15376.1 CDJ66272.1 - 5.6 4.0 20.6 7.3 3.6 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF966 PF06136.8 CDJ66272.1 - 5.7 6.2 19.7 6.5 6.0 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.12 CDJ66272.1 - 5.8 5.6 21.1 7.3 5.3 14.6 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.1 CDJ66272.1 - 6.1 6.5 15.1 9.2 5.9 10.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A GATase PF00117.23 CDJ66273.1 - 6e-47 159.5 0.0 8e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CDJ66273.1 - 3.6e-06 26.5 0.0 3.6e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase C26 SHR3_chaperone PF08229.6 CDJ66273.1 - 0.24 10.3 2.9 0.38 9.6 2.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 GDA1_CD39 PF01150.12 CDJ66274.1 - 8.6e-49 166.1 0.0 1.3e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family CRAL_TRIO PF00650.15 CDJ66275.1 - 1.1e-11 44.4 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRA PF06589.6 CDJ66275.1 - 0.014 14.6 0.1 0.039 13.2 0.0 1.7 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Pex14_N PF04695.8 CDJ66275.1 - 0.039 14.0 10.0 0.059 13.4 7.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDJ66275.1 - 0.21 11.3 10.2 0.3 10.7 7.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Shisa PF13908.1 CDJ66275.1 - 2.3 8.3 8.2 3.5 7.7 5.7 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1183 PF06682.7 CDJ66276.1 - 2.1 7.8 6.3 0.27 10.7 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) SelP_N PF04592.9 CDJ66276.1 - 6.7 6.0 15.8 10 5.4 11.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SRRM_C PF15230.1 CDJ66277.1 - 3.2 7.8 7.4 1.6 8.8 3.6 1.6 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus SNF2_N PF00176.18 CDJ66278.1 - 2.7e-48 164.2 0.0 3.3e-39 134.4 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CDJ66278.1 - 3.4e-13 49.2 0.0 6.8e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDJ66278.1 - 3.1e-05 23.5 0.0 6.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDJ66278.1 - 0.00019 21.3 0.0 0.00059 19.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nop25 PF09805.4 CDJ66278.1 - 2.3 8.3 12.1 0.35 10.9 5.0 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Bap31 PF05529.7 CDJ66279.1 - 6.9 6.0 6.9 21 4.4 4.8 1.8 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PNTB PF02233.11 CDJ66280.1 - 5.9e-170 566.0 20.9 2.2e-139 465.2 5.0 2.5 1 1 1 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 CDJ66280.1 - 9.5e-48 161.9 0.4 1.6e-47 161.1 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 CDJ66280.1 - 2.8e-20 72.6 0.0 6.5e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 CDJ66280.1 - 4e-12 46.1 5.3 4e-12 46.1 3.7 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 CDJ66280.1 - 1e-05 24.7 0.1 0.077 12.1 0.1 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 CDJ66280.1 - 0.00037 20.2 0.1 0.0022 17.7 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.15 CDJ66280.1 - 0.036 14.1 0.9 5.8 7.0 0.3 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 CDJ66280.1 - 0.09 12.6 0.3 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 CDJ66280.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2454 PF10521.4 CDJ66281.1 - 0.0025 16.8 0.2 0.0089 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) AAA_11 PF13086.1 CDJ66282.1 - 4.8e-68 229.2 0.0 5.9e-67 225.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CDJ66282.1 - 1.2e-56 191.2 0.0 2.4e-56 190.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDJ66282.1 - 8.2e-10 38.3 0.1 1.3e-05 24.7 0.3 3.3 2 1 1 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 CDJ66282.1 - 2.5e-07 30.4 2.4 0.0031 17.0 0.1 3.3 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 CDJ66282.1 - 0.00084 18.9 0.3 0.093 12.2 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CDJ66282.1 - 0.019 14.2 0.0 1.6 7.9 0.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Transaldolase PF00923.14 CDJ66286.1 - 1.4e-09 37.4 0.7 1.5e-09 37.4 0.5 1.0 1 0 0 1 1 1 1 Transaldolase DUF615 PF04751.9 CDJ66286.1 - 0.0049 16.5 1.1 0.0051 16.4 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF615) Imm31 PF15595.1 CDJ66286.1 - 0.13 12.0 0.3 0.17 11.6 0.2 1.4 1 1 0 1 1 1 0 Immunity protein 31 DUF3846 PF12957.2 CDJ66288.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) DUF1084 PF06454.6 CDJ66289.1 - 1.8e-09 37.0 4.0 3.1e-09 36.2 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) hDGE_amylase PF14701.1 CDJ66291.1 - 2.2 7.0 11.3 3.4 6.4 7.0 1.6 1 1 1 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme ALMT PF11744.3 CDJ66291.1 - 6.6 5.2 13.4 10 4.6 6.2 2.5 1 1 2 3 3 3 0 Aluminium activated malate transporter DUF4407 PF14362.1 CDJ66291.1 - 9.3 5.1 29.3 0.0084 15.0 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nol1_Nop2_Fmu PF01189.12 CDJ66292.1 - 6.5e-19 68.3 0.0 2.9e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CDJ66292.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 CDJ66292.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CDJ66292.1 - 0.035 13.6 0.0 0.88 9.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ66292.1 - 0.09 13.3 0.0 0.21 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF4351 PF14261.1 CDJ66294.1 - 0.023 14.5 0.5 0.046 13.5 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) DUF3380 PF11860.3 CDJ66295.1 - 0.038 14.0 0.2 0.041 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3380) DUF4633 PF15464.1 CDJ66295.1 - 0.1 12.4 0.4 0.16 11.8 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4633) IBN_N PF03810.14 CDJ66296.1 - 1.1e-05 25.2 0.9 3.1e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Pex2_Pex12 PF04757.9 CDJ66297.1 - 3.7e-18 65.7 0.0 1.9e-17 63.5 0.0 2.2 2 1 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CDJ66297.1 - 0.00027 20.8 6.4 0.00052 19.9 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDJ66297.1 - 0.0019 17.8 2.6 0.0044 16.6 1.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ66297.1 - 0.0021 17.8 6.3 0.0036 17.0 3.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 CDJ66297.1 - 1.8 8.5 6.1 4.4 7.2 4.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2217 PF10265.4 CDJ66297.1 - 4.5 5.9 5.6 0.46 9.1 0.6 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) gag_pre-integrs PF13976.1 CDJ66297.1 - 6.6 6.4 6.5 0.8 9.3 0.1 2.7 3 0 0 3 3 3 0 GAG-pre-integrase domain Sybindin PF04099.7 CDJ66298.1 - 4.8e-18 65.2 0.0 5.8e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family ABC1 PF03109.11 CDJ66300.1 - 4.9e-29 100.7 0.0 9e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CDJ66300.1 - 0.23 10.7 0.0 0.48 9.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FHIPEP PF00771.15 CDJ66300.1 - 0.41 8.9 2.1 0.86 7.8 1.5 1.4 1 0 0 1 1 1 0 FHIPEP family Rpp20 PF12328.3 CDJ66300.1 - 4.2 7.0 7.1 6.4 6.4 1.6 2.8 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P MORN PF02493.15 CDJ66301.1 - 1e-20 72.1 14.7 5.5e-07 28.9 0.3 3.3 3 0 0 3 3 3 3 MORN repeat Lipoprotein_5 PF01298.13 CDJ66301.1 - 0.043 12.7 0.3 0.076 11.9 0.2 1.4 1 1 1 2 2 2 0 Transferrin binding protein-like solute binding protein Lebercilin PF15619.1 CDJ66302.1 - 0.0011 18.4 0.1 0.0013 18.2 0.1 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF1631 PF07793.6 CDJ66302.1 - 0.057 11.5 0.1 0.063 11.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) V_ATPase_I PF01496.14 CDJ66302.1 - 0.059 11.2 0.1 0.066 11.0 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PfkB PF00294.19 CDJ66302.1 - 0.076 12.1 0.1 0.078 12.0 0.1 1.0 1 0 0 1 1 1 0 pfkB family carbohydrate kinase RPN7 PF10602.4 CDJ66302.1 - 0.11 11.9 0.7 0.12 11.7 0.5 1.1 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Cwf_Cwc_15 PF04889.7 CDJ66303.1 - 0.0069 16.1 6.3 0.0069 16.1 4.4 5.9 4 2 1 5 5 5 1 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.8 CDJ66304.1 - 7.4 4.5 17.2 8.7 4.3 11.9 1.0 1 0 0 1 1 1 0 Utp14 protein Protamine_P2 PF00841.14 CDJ66306.1 - 0.012 16.1 11.6 0.012 16.1 8.0 2.4 2 0 0 2 2 2 0 Sperm histone P2 U1snRNP70_N PF12220.3 CDJ66306.1 - 4.6 7.6 11.5 1.1 9.6 1.6 2.6 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UPF1_Zn_bind PF09416.5 CDJ66307.1 - 3.6e-15 55.8 0.1 3.9e-15 55.7 0.1 1.0 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) zf-UBR PF02207.15 CDJ66309.1 - 4.8e-10 39.0 5.9 1.3e-09 37.6 4.1 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) SPX PF03105.14 CDJ66309.1 - 0.022 14.5 6.6 2.8 7.6 4.1 2.6 2 0 0 2 2 2 0 SPX domain Neur_chan_memb PF02932.11 CDJ66309.1 - 0.11 12.4 2.4 4.3 7.1 1.0 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CRT10 PF08728.5 CDJ66309.1 - 0.65 7.9 0.1 1 7.2 0.1 1.2 1 0 0 1 1 1 0 CRT10 GRP PF07172.6 CDJ66309.1 - 1 9.8 9.7 1.1 9.7 0.2 2.9 2 0 0 2 2 2 0 Glycine rich protein family SAGA-Tad1 PF12767.2 CDJ66309.1 - 1.1 8.8 22.7 0.29 10.7 5.4 3.5 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Pkinase PF00069.20 CDJ66310.1 - 4.8e-06 25.9 0.0 4.9e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain ThiF PF00899.16 CDJ66313.1 - 2.2e-07 30.7 0.0 6.4e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 ThiF family DUF3110 PF11360.3 CDJ66313.1 - 0.0023 17.7 0.2 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) CK_II_beta PF01214.13 CDJ66313.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Casein kinase II regulatory subunit RAP1 PF07218.6 CDJ66313.1 - 1.9 6.4 2.7 3.1 5.7 1.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MCM2_N PF12619.3 CDJ66314.1 - 2.7e-06 27.4 12.9 2.7e-06 27.4 8.9 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CDJ66314.1 - 0.00016 22.1 0.0 0.00026 21.4 0.0 1.3 1 1 0 1 1 1 1 MCM N-terminal domain Shadoo PF14999.1 CDJ66314.1 - 0.0088 15.9 3.7 0.0088 15.9 2.6 2.3 3 0 0 3 3 3 1 Shadow of prion protein, neuroprotective DUF1509 PF07420.6 CDJ66314.1 - 1.9 7.7 6.4 0.44 9.7 2.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) SR-25 PF10500.4 CDJ66315.1 - 0.00049 19.6 21.3 0.00049 19.6 14.8 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDJ66315.1 - 0.0083 15.4 60.2 0.011 15.1 41.7 1.0 1 0 0 1 1 1 1 SprA-related family MIP-T3 PF10243.4 CDJ66315.1 - 0.08 11.4 39.3 0.093 11.1 27.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 CDJ66315.1 - 0.1 11.9 35.1 0.13 11.6 24.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDJ66315.1 - 0.15 10.2 71.9 0.17 10.1 49.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAP1 PF07218.6 CDJ66315.1 - 0.36 8.8 2.0 0.36 8.8 1.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Med15 PF09606.5 CDJ66315.1 - 0.9 7.6 87.1 1.1 7.3 60.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MSP1_C PF07462.6 CDJ66315.1 - 5.3 5.3 7.7 6.4 5.0 5.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PBP_sp32 PF07222.7 CDJ66316.1 - 0.25 10.4 9.4 0.23 10.5 6.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2992 PF11208.3 CDJ66316.1 - 0.3 10.9 18.0 0.35 10.7 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Med15 PF09606.5 CDJ66316.1 - 0.43 8.7 27.0 0.44 8.6 18.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDJ66316.1 - 2.3 6.8 4.3 1.9 7.1 3.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.12 CDJ66316.1 - 4 7.1 9.2 4 7.1 6.4 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.12 CDJ66316.1 - 5.3 5.7 5.2 5.2 5.7 3.6 1.1 1 0 0 1 1 1 0 Presenilin Gastrin PF00918.12 CDJ66316.1 - 9.3 7.1 16.4 9.2 7.1 10.6 1.5 1 1 0 1 1 1 0 Gastrin/cholecystokinin family Pkinase PF00069.20 CDJ66318.1 - 6.7e-38 130.3 0.0 6.7e-38 130.3 0.0 3.9 5 0 0 5 5 5 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ66318.1 - 1.1e-26 93.4 0.8 3e-25 88.7 0.0 3.6 2 1 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CDJ66318.1 - 3.1 6.5 0.0 5 5.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 CDJ66319.1 - 1.5e-21 76.6 0.0 3.3e-15 55.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ66319.1 - 6.4e-10 38.5 0.0 0.00059 18.9 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CDJ66319.1 - 0.072 12.8 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cep57_CLD_2 PF14197.1 CDJ66321.1 - 8e-06 25.7 1.3 8e-06 25.7 0.9 5.4 4 1 2 6 6 6 1 Centrosome localisation domain of PPC89 FH2 PF02181.18 CDJ66321.1 - 4.6e-05 22.4 0.1 4.6e-05 22.4 0.0 3.2 2 1 1 3 3 3 1 Formin Homology 2 Domain DUF3045 PF11243.3 CDJ66321.1 - 0.29 11.3 0.0 0.63 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) DUF755 PF05501.6 CDJ66322.1 - 0.0022 18.0 25.0 0.0029 17.6 17.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF755) CDK2AP PF09806.4 CDJ66322.1 - 0.046 13.9 16.3 0.051 13.8 11.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.6 CDJ66322.1 - 0.1 11.9 9.4 0.1 11.9 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Calici_coat_C PF08435.6 CDJ66322.1 - 0.13 11.5 2.8 0.14 11.4 1.9 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Cwf_Cwc_15 PF04889.7 CDJ66322.1 - 0.39 10.4 8.9 0.41 10.3 6.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TSA PF03249.8 CDJ66322.1 - 0.74 8.2 7.5 0.87 8.0 5.2 1.1 1 0 0 1 1 1 0 Type specific antigen AF-4 PF05110.8 CDJ66322.1 - 0.81 7.4 28.9 0.94 7.2 20.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Draxin PF15550.1 CDJ66322.1 - 0.86 9.1 6.1 0.94 9.0 4.2 1.0 1 0 0 1 1 1 0 Draxin FAM60A PF15396.1 CDJ66322.1 - 1.5 8.5 10.7 1.5 8.4 7.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Apc15p PF05841.6 CDJ66322.1 - 2.1 9.0 12.9 2.6 8.8 8.9 1.1 1 0 0 1 1 1 0 Apc15p protein DUF2217 PF10265.4 CDJ66322.1 - 2.2 6.9 15.9 2.3 6.8 11.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MACPF PF01823.14 CDJ66322.1 - 2.7 7.6 10.8 3 7.4 7.5 1.1 1 0 0 1 1 1 0 MAC/Perforin domain Lin-8 PF03353.10 CDJ66322.1 - 2.8 7.1 11.3 2.9 7.1 7.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3138 PF11336.3 CDJ66322.1 - 3.1 5.8 7.6 3.1 5.8 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF572 PF04502.8 CDJ66322.1 - 3.2 6.9 11.1 3.3 6.8 7.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_pp85 PF04637.7 CDJ66322.1 - 3.2 5.9 9.0 3.4 5.8 6.3 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mcm10 PF09332.6 CDJ66322.1 - 3.4 6.9 11.0 3.6 6.8 7.6 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Gag_spuma PF03276.9 CDJ66322.1 - 3.4 5.8 11.6 3.5 5.8 8.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Plasmodium_Vir PF05795.6 CDJ66322.1 - 4.3 6.4 7.3 4.6 6.3 5.1 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLD3 PF08639.5 CDJ66322.1 - 4.7 5.7 16.7 4.7 5.7 11.6 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF2051 PF09738.4 CDJ66322.1 - 6.7 5.9 12.6 7.3 5.7 8.7 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) FNIP_N PF14636.1 CDJ66322.1 - 9 6.7 15.2 9.9 6.6 10.5 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus NTP_transf_3 PF12804.2 CDJ66323.1 - 0.061 13.3 5.4 0.077 13.0 0.0 2.9 2 1 0 3 3 3 0 MobA-like NTP transferase domain SR-25 PF10500.4 CDJ66323.1 - 0.37 10.2 7.5 0.66 9.4 5.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDJ66323.1 - 0.52 10.7 34.5 0.075 13.4 6.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein CDK2AP PF09806.4 CDJ66323.1 - 0.76 9.9 15.4 0.11 12.6 2.1 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF2057 PF09829.4 CDJ66323.1 - 4.3 6.9 5.4 4 7.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) UAA PF08449.6 CDJ66324.1 - 3.1e-62 210.2 15.9 3.8e-62 209.9 11.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CDJ66324.1 - 3.2e-07 30.4 22.9 1.2e-05 25.2 3.2 3.1 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CDJ66324.1 - 1.8e-06 27.2 8.8 0.011 14.8 0.9 3.1 3 0 0 3 3 3 2 Nucleotide-sugar transporter TPT PF03151.11 CDJ66324.1 - 0.0003 20.4 6.1 0.0003 20.4 4.3 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family Pex14_N PF04695.8 CDJ66324.1 - 0.81 9.7 3.9 0.88 9.6 1.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3681 PF12442.3 CDJ66324.1 - 2.2 8.5 9.4 3.1 8.0 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3681) DUF3272 PF11676.3 CDJ66324.1 - 4.8 7.2 12.2 1.6 8.7 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) DUF755 PF05501.6 CDJ66325.1 - 0.002 18.1 18.6 0.002 18.1 12.9 5.1 4 1 0 4 4 4 1 Domain of unknown function (DUF755) SpoIIIAH PF12685.2 CDJ66325.1 - 0.049 13.1 28.7 0.36 10.3 0.8 4.2 3 1 0 3 3 3 0 SpoIIIAH-like protein CATSPERD PF15020.1 CDJ66325.1 - 0.65 7.9 1.3 0.95 7.3 0.9 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Hid1 PF12722.2 CDJ66325.1 - 1.1 6.8 13.5 0.039 11.6 2.2 2.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.6 CDJ66325.1 - 1.1 8.4 10.7 0.35 10.0 1.2 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Spt20 PF12090.3 CDJ66325.1 - 2.1 7.6 10.0 0.85 8.9 2.5 2.4 2 0 0 2 2 2 0 Spt20 family DUF3141 PF11339.3 CDJ66325.1 - 2.3 6.4 8.3 3.8 5.7 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) zf-DHHC PF01529.15 CDJ66325.1 - 2.6 7.4 5.1 5 6.4 2.9 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CDJ66325.1 - 2.7 8.2 12.9 16 5.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain Mem_trans PF03547.13 CDJ66325.1 - 8.5 4.5 8.2 15 3.7 1.9 2.4 2 0 0 2 2 2 0 Membrane transport protein Ribosomal_60s PF00428.14 CDJ66326.1 - 0.016 15.5 38.4 0.24 11.8 0.9 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF572 PF04502.8 CDJ66326.1 - 0.048 12.8 14.9 0.1 11.7 10.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_60s PF00428.14 CDJ66327.1 - 0.41 11.0 11.3 0.45 10.9 7.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein TALPID3 PF15324.1 CDJ66327.1 - 0.65 7.2 8.3 0.69 7.1 5.8 1.2 1 0 0 1 1 1 0 Hedgehog signalling target BAF1_ABF1 PF04684.8 CDJ66327.1 - 1 8.1 17.6 1.1 8.0 12.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex16 PF08610.5 CDJ66327.1 - 1.6 7.6 4.2 1.6 7.6 2.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) YihI PF04220.7 CDJ66327.1 - 2.7 7.2 9.7 3 7.1 6.5 1.3 1 1 1 2 2 2 0 Der GTPase activator (YihI) PRKCSH PF07915.8 CDJ66327.1 - 3.5 8.4 5.7 3.9 8.3 4.0 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein BRF1 PF07741.8 CDJ66327.1 - 5 7.4 10.0 6.3 7.0 6.9 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain MORN PF02493.15 CDJ66328.1 - 3.9e-31 104.8 39.9 3e-08 32.9 0.7 7.6 7 1 0 7 7 7 5 MORN repeat GTP_EFTU_D2 PF03144.20 CDJ66328.1 - 0.08 13.0 0.0 22 5.2 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Kin17_mid PF10357.4 CDJ66328.1 - 0.3 10.7 7.0 0.44 10.2 4.9 1.2 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein Leo1 PF04004.8 CDJ66329.1 - 2.8e-10 40.1 0.1 7e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Leo1-like protein DUF3700 PF12481.3 CDJ66329.1 - 0.073 12.2 0.3 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 Aluminium induced protein PHD_3 PF13922.1 CDJ66329.1 - 2.5 8.3 7.6 16 5.8 5.3 2.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Ipi1_N PF12333.3 CDJ66330.1 - 0.025 14.5 1.6 0.053 13.4 1.1 1.4 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Spt20 PF12090.3 CDJ66330.1 - 5.5 6.2 9.6 0.1 11.9 1.3 2.0 2 0 0 2 2 2 0 Spt20 family RskA PF10099.4 CDJ66331.1 - 0.014 15.1 9.4 0.043 13.5 2.2 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MIP-T3 PF10243.4 CDJ66331.1 - 0.69 8.3 31.1 0.88 7.9 21.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Bac_luciferase PF00296.15 CDJ66331.1 - 4.7 6.2 11.2 1.3 8.0 3.6 2.1 2 0 0 2 2 2 0 Luciferase-like monooxygenase CK_II_beta PF01214.13 CDJ66332.1 - 2e-42 144.8 0.2 3.3e-41 140.8 0.0 2.1 2 0 0 2 2 2 1 Casein kinase II regulatory subunit Na_trans_assoc PF06512.8 CDJ66332.1 - 0.014 15.4 8.8 0.02 14.8 6.1 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Med15 PF09606.5 CDJ66332.1 - 0.025 12.8 27.4 0.032 12.4 19.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal WES_acyltransf PF03007.11 CDJ66332.1 - 0.09 12.3 7.0 0.13 11.7 4.8 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Pol_alpha_B_N PF08418.5 CDJ66332.1 - 0.13 11.7 13.8 0.23 10.9 9.5 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3138 PF11336.3 CDJ66332.1 - 0.19 9.8 14.3 0.25 9.4 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4647 PF15504.1 CDJ66332.1 - 0.59 8.9 10.0 0.77 8.5 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Macoilin PF09726.4 CDJ66332.1 - 0.59 8.3 24.6 0.77 7.9 17.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_60s PF00428.14 CDJ66332.1 - 0.62 10.5 17.9 0.49 10.8 10.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Neur_chan_memb PF02932.11 CDJ66332.1 - 0.7 9.7 8.1 0.99 9.2 5.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1675 PF07897.6 CDJ66332.1 - 0.93 9.3 16.4 1.2 8.8 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hamartin PF04388.7 CDJ66332.1 - 1.6 7.2 14.6 2.1 6.9 10.1 1.1 1 0 0 1 1 1 0 Hamartin protein Spc7_N PF15402.1 CDJ66332.1 - 1.8 6.4 21.3 2.3 6.0 14.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CDC27 PF09507.5 CDJ66332.1 - 4.4 6.4 19.9 5.6 6.0 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RskA PF10099.4 CDJ66332.1 - 6.1 6.5 16.7 12 5.5 11.6 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PAT1 PF09770.4 CDJ66332.1 - 8.1 4.5 24.7 10 4.2 17.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_6 PF14259.1 CDJ66333.1 - 0.0036 17.2 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 CDJ66334.1 - 0.00063 18.1 55.1 0.0008 17.7 38.2 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.10 CDJ66336.1 - 0.12 11.6 0.2 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF592 PF04574.8 CDJ66337.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) RNA_pol_Rpb1_R PF05001.8 CDJ66338.1 - 0.035 14.2 4.0 0.13 12.4 2.8 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat AAA_6 PF12774.2 CDJ66340.1 - 6.5e-84 281.0 3.3 1.3e-83 280.0 0.1 3.1 5 0 0 5 5 4 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CDJ66340.1 - 7.9e-63 211.9 0.2 4.7e-62 209.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CDJ66340.1 - 1.5e-53 181.6 0.0 4.8e-53 179.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDJ66340.1 - 4.5e-28 97.7 0.0 4e-09 36.3 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CDJ66340.1 - 3.6e-12 46.6 0.0 0.0053 16.9 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDJ66340.1 - 4.2e-08 33.4 0.1 0.46 10.6 0.0 4.6 4 0 0 4 4 3 3 AAA domain AAA_17 PF13207.1 CDJ66340.1 - 5.6e-08 33.6 0.0 0.011 16.5 0.0 5.1 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.1 CDJ66340.1 - 4.1e-07 30.3 0.0 0.063 13.5 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CDJ66340.1 - 5.3e-07 29.2 1.1 0.09 12.5 0.1 4.0 3 0 0 3 3 3 2 Part of AAA domain DUF853 PF05872.7 CDJ66340.1 - 1.4e-06 26.9 0.4 0.23 9.7 0.0 3.2 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.1 CDJ66340.1 - 6.9e-06 26.1 4.6 3 7.7 0.0 6.1 6 1 1 7 7 5 1 AAA ATPase domain RNA_helicase PF00910.17 CDJ66340.1 - 1e-05 25.6 0.0 0.1 12.7 0.0 4.2 3 0 0 3 3 3 1 RNA helicase Zeta_toxin PF06414.7 CDJ66340.1 - 2.2e-05 23.6 0.1 0.035 13.1 0.0 3.3 4 0 0 4 4 4 1 Zeta toxin AAA_28 PF13521.1 CDJ66340.1 - 7.5e-05 22.7 1.2 3.3 7.6 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.1 CDJ66340.1 - 0.00013 21.6 0.3 0.87 9.1 0.1 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 CDJ66340.1 - 0.00021 20.3 2.3 0.91 8.3 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein Mg_chelatase PF01078.16 CDJ66340.1 - 0.00022 20.4 0.7 3.2 6.8 0.0 4.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI DEAD PF00270.24 CDJ66340.1 - 0.00063 19.2 0.1 0.98 8.8 0.0 3.7 4 0 0 4 4 4 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 CDJ66340.1 - 0.00068 19.0 0.1 3.2 7.1 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein SRP54 PF00448.17 CDJ66340.1 - 0.0007 19.1 0.4 1.1 8.7 0.0 3.8 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 CDJ66340.1 - 0.00077 19.0 1.0 3.6 7.2 0.1 3.6 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 CDJ66340.1 - 0.00087 19.1 0.4 10 5.8 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 CDJ66340.1 - 0.00095 19.0 0.0 1.6 8.6 0.0 3.5 4 0 0 4 4 2 1 AAA domain AAA_33 PF13671.1 CDJ66340.1 - 0.001 18.9 0.1 18 5.2 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.1 CDJ66340.1 - 0.0018 17.6 4.6 1.6 8.1 0.1 4.2 5 0 0 5 5 4 1 AAA domain DHC_N2 PF08393.8 CDJ66340.1 - 0.011 14.2 0.6 0.032 12.7 0.0 2.1 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 NACHT PF05729.7 CDJ66340.1 - 0.013 15.1 0.7 26 4.4 0.0 4.3 3 1 0 3 3 3 0 NACHT domain AAA_2 PF07724.9 CDJ66340.1 - 0.064 13.1 0.0 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) DUF4533 PF15047.1 CDJ66340.1 - 0.14 11.6 2.9 0.69 9.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4533) MobB PF03205.9 CDJ66340.1 - 0.18 11.5 0.8 66 3.1 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CDJ66340.1 - 0.23 11.7 0.4 28 4.9 0.0 3.4 3 0 0 3 3 3 0 ABC transporter PriCT_1 PF08708.6 CDJ66340.1 - 0.25 11.1 2.1 17 5.3 0.0 3.8 4 0 0 4 4 3 0 Primase C terminal 1 (PriCT-1) Sec2p PF06428.6 CDJ66340.1 - 0.4 10.5 4.6 0.52 10.1 1.3 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p AAA_24 PF13479.1 CDJ66340.1 - 4.4 6.8 5.1 52 3.3 0.4 3.3 4 0 0 4 4 3 0 AAA domain Dynein_heavy PF03028.10 CDJ66341.1 - 4.9e-223 742.1 0.0 2.3e-222 739.9 0.0 2.0 2 1 1 3 3 3 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 CDJ66341.1 - 1.9e-51 174.1 0.0 3.7e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MEDS PF14417.1 CDJ66341.1 - 0.023 13.7 0.4 0.047 12.7 0.3 1.5 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF2316 PF10078.4 CDJ66341.1 - 0.11 12.5 1.0 8 6.5 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Cullin_Nedd8 PF10557.4 CDJ66344.1 - 8.1e-11 41.5 1.6 6e-10 38.7 1.1 2.1 1 1 0 1 1 1 1 Cullin protein neddylation domain HTH_29 PF13551.1 CDJ66344.1 - 0.014 15.5 3.5 0.086 12.9 0.4 2.7 1 1 1 2 2 2 0 Winged helix-turn helix HTH_32 PF13565.1 CDJ66344.1 - 0.063 14.0 0.6 0.17 12.6 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Gastrin PF00918.12 CDJ66344.1 - 0.078 13.7 0.2 4.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Cullin PF00888.17 CDJ66344.1 - 0.096 11.2 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Cullin family Calreticulin PF00262.13 CDJ66345.1 - 4.4e-34 117.7 0.0 1.2e-32 112.9 0.0 2.1 2 0 0 2 2 2 2 Calreticulin family Peptidase_C65 PF10275.4 CDJ66345.1 - 0.04 13.2 0.2 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain SR-25 PF10500.4 CDJ66347.1 - 0.00053 19.5 29.3 0.0071 15.8 10.8 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Mitofilin PF09731.4 CDJ66347.1 - 0.0033 16.1 10.3 0.0045 15.7 7.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein FeoA PF04023.9 CDJ66347.1 - 0.028 14.3 0.2 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 FeoA domain TraG-D_C PF12696.2 CDJ66347.1 - 1.3 8.8 6.6 3.6 7.4 0.0 2.1 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG TFIIA PF03153.8 CDJ66347.1 - 3.4 7.4 10.3 4.3 7.1 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2638 PF10937.3 CDJ66347.1 - 8.3 7.4 11.2 0.2 12.6 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) Med15 PF09606.5 CDJ66348.1 - 0.00034 18.9 40.2 0.017 13.3 6.3 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDJ66348.1 - 0.055 13.1 17.2 0.016 14.9 3.5 2.6 2 1 0 2 2 2 0 Anti-sigma-K factor rskA BRF1 PF07741.8 CDJ66348.1 - 0.069 13.3 12.2 0.6 10.3 5.1 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain MRP-S31 PF15433.1 CDJ66348.1 - 0.099 12.0 12.9 0.5 9.7 4.8 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 TMEM51 PF15345.1 CDJ66348.1 - 0.12 12.0 13.4 1.8 8.2 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Pap_E4 PF02711.9 CDJ66348.1 - 0.16 12.8 10.1 1.1 10.0 3.9 2.4 2 0 0 2 2 2 0 E4 protein DUF2048 PF09752.4 CDJ66348.1 - 0.17 10.7 13.6 1.2 7.9 3.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) SeqA PF03925.8 CDJ66348.1 - 0.18 11.5 7.0 0.4 10.3 2.2 2.1 2 0 0 2 2 2 0 SeqA protein Suf PF05843.9 CDJ66348.1 - 0.28 10.8 15.9 0.8 9.3 5.5 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Raftlin PF15250.1 CDJ66348.1 - 0.38 9.2 12.4 0.53 8.7 5.6 2.0 2 0 0 2 2 2 0 Raftlin Band_3_cyto PF07565.8 CDJ66348.1 - 0.41 10.1 11.7 0.19 11.2 2.3 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Gti1_Pac2 PF09729.4 CDJ66348.1 - 0.42 10.4 6.9 0.29 11.0 1.4 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family HA2 PF04408.18 CDJ66348.1 - 0.49 10.4 6.2 9.9 6.2 1.7 2.4 2 0 0 2 2 2 0 Helicase associated domain (HA2) RED_N PF07808.8 CDJ66348.1 - 0.52 9.4 25.0 0.11 11.7 2.0 2.1 2 0 0 2 2 2 0 RED-like protein N-terminal region Presenilin PF01080.12 CDJ66348.1 - 0.61 8.8 4.7 6.3 5.5 0.0 2.2 2 0 0 2 2 2 0 Presenilin DUF3043 PF11241.3 CDJ66348.1 - 0.66 9.5 13.3 0.52 9.8 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) OmpH PF03938.9 CDJ66348.1 - 0.78 9.6 42.5 1.3 8.9 29.3 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Spore_coat_CotO PF14153.1 CDJ66348.1 - 0.89 8.9 18.0 0.23 10.9 5.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Pex14_N PF04695.8 CDJ66348.1 - 2.6 8.1 21.5 0.59 10.1 5.5 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.7 CDJ66348.1 - 2.7 6.5 17.0 0.73 8.3 6.2 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 CDJ66348.1 - 2.7 7.7 11.1 2.8 7.7 3.9 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Miff PF05644.6 CDJ66348.1 - 3 7.4 9.9 0.38 10.3 3.1 1.9 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff DUF4557 PF15101.1 CDJ66348.1 - 3 7.6 27.7 0.92 9.3 9.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Peptidase_S49_N PF08496.5 CDJ66348.1 - 3.1 7.5 16.4 1.2 8.8 6.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FimP PF09766.4 CDJ66348.1 - 3.7 6.5 30.5 0.64 9.0 10.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein Folliculin PF11704.3 CDJ66348.1 - 5 6.6 10.6 12 5.3 0.1 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Hom_end_hint PF05203.11 CDJ66348.1 - 5.8 6.5 7.9 2.9 7.5 1.2 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint Peptidase_U57 PF05582.7 CDJ66348.1 - 6.5 5.6 10.5 1.8 7.4 2.8 2.1 2 0 0 2 2 2 0 YabG peptidase U57 Dala_Dala_lig_N PF01820.16 CDJ66348.1 - 8 6.8 7.5 7.2 6.9 1.7 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF912 PF06024.7 CDJ66348.1 - 8.1 6.5 10.3 2 8.5 2.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Kei1 PF08552.6 CDJ66348.1 - 8.9 5.9 8.9 4.8 6.7 1.9 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 ATAD4 PF15321.1 CDJ66348.1 - 9.9 7.2 15.8 13 6.8 0.8 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 tRNA-synt_1e PF01406.14 CDJ66349.1 - 1.8e-25 89.6 0.0 2.2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF2217 PF10265.4 CDJ66349.1 - 2.5 6.7 7.6 2.8 6.5 5.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Herpes_capsid PF06112.6 CDJ66349.1 - 2.8 7.9 16.1 4.1 7.4 11.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.4 CDJ66349.1 - 5.2 5.2 6.2 6.2 4.9 4.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1117 PF06547.7 CDJ66349.1 - 6.3 6.9 11.6 6.6 6.8 7.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) YycC PF14174.1 CDJ66350.1 - 0.008 15.8 1.5 0.008 15.8 1.0 2.3 2 0 0 2 2 2 1 YycC-like protein DUF3115 PF11312.3 CDJ66350.1 - 1.3 7.7 8.4 2.1 7.0 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3115) DUF4551 PF15087.1 CDJ66350.1 - 2.6 6.3 14.9 3.1 6.0 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pheromone PF08015.6 CDJ66350.1 - 3.8 8.3 5.8 1.8 9.4 2.4 1.8 2 0 0 2 2 2 0 Fungal mating-type pheromone Dicty_REP PF05086.7 CDJ66351.1 - 0.56 7.8 3.0 1.1 6.9 2.1 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SAPS PF04499.10 CDJ66353.1 - 0.34 9.5 11.0 0.44 9.1 7.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDJ66353.1 - 0.86 7.2 7.3 1 6.9 5.1 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDJ66353.1 - 2.3 5.8 15.3 2.6 5.6 10.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF940 PF06082.6 CDJ66353.1 - 2.7 6.4 10.8 3.1 6.2 7.5 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) FLO_LFY PF01698.11 CDJ66353.1 - 4.8 5.9 12.0 6.8 5.4 8.3 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein zf-CCHC PF00098.18 CDJ66354.1 - 4.2e-08 32.7 14.1 4.4e-06 26.3 1.5 3.5 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ66354.1 - 0.0013 18.4 0.2 0.0013 18.4 0.1 2.4 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ66354.1 - 0.0036 16.9 0.8 0.0036 16.9 0.6 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ66354.1 - 0.014 15.0 7.7 0.041 13.5 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 CDJ66354.1 - 0.15 11.5 5.5 0.094 12.2 0.5 2.5 1 1 1 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ66354.1 - 0.24 11.4 11.4 0.51 10.4 7.9 1.6 1 0 0 1 1 1 0 DnaJ central domain NYAP_N PF15439.1 CDJ66355.1 - 0.0081 15.3 6.9 0.064 12.4 3.4 2.7 1 1 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DDOST_48kD PF03345.9 CDJ66356.1 - 4.7e-45 153.8 0.0 5.6e-42 143.7 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta 2OG-FeII_Oxy_3 PF13640.1 CDJ66356.1 - 4e-09 36.8 0.0 1.1e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 CDJ66356.1 - 0.0076 15.0 0.0 0.02 13.6 0.0 1.5 1 1 1 2 2 2 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy_5 PF13759.1 CDJ66356.1 - 0.024 14.9 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase zf-C3HC4_2 PF13923.1 CDJ66357.1 - 0.0023 17.9 0.4 0.0055 16.6 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3613 PF12266.3 CDJ66357.1 - 0.0043 16.5 1.9 0.0043 16.5 1.3 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3613) DUF1754 PF08555.5 CDJ66357.1 - 0.13 12.8 0.2 0.13 12.8 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF4319 PF14203.1 CDJ66358.1 - 2 8.0 6.5 0.83 9.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) Bud13 PF09736.4 CDJ66359.1 - 6.1e-37 127.0 4.6 6.1e-37 127.0 3.2 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex AAA PF00004.24 CDJ66360.1 - 1.5e-39 135.2 0.0 3e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDJ66360.1 - 3.5e-05 23.9 0.1 0.042 13.9 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 CDJ66360.1 - 0.00024 21.1 6.2 0.002 18.1 0.1 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CDJ66360.1 - 0.00058 19.5 0.1 0.0026 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CDJ66360.1 - 0.0013 18.3 0.3 0.0047 16.6 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 CDJ66360.1 - 0.0024 16.6 0.3 0.0052 15.5 0.1 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 CDJ66360.1 - 0.0052 17.5 0.4 0.022 15.5 0.3 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CDJ66360.1 - 0.0097 14.9 0.0 0.042 12.9 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CDJ66360.1 - 0.011 15.1 0.1 0.011 15.1 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 CDJ66360.1 - 0.012 14.8 0.6 0.022 13.9 0.4 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 CDJ66360.1 - 0.013 14.6 0.1 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 CDJ66360.1 - 0.02 14.5 0.9 0.095 12.3 0.1 2.5 2 1 1 3 3 3 0 NACHT domain AAA_33 PF13671.1 CDJ66360.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CDJ66360.1 - 0.032 14.1 0.4 0.063 13.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 CDJ66360.1 - 0.039 14.2 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CDJ66360.1 - 0.05 12.7 0.2 0.13 11.4 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CDJ66360.1 - 0.41 10.0 2.2 0.64 9.3 0.6 1.9 2 1 0 2 2 2 0 AAA domain P12 PF12669.2 CDJ66360.1 - 2.3 8.4 6.4 8 6.7 0.0 3.0 3 0 0 3 3 3 0 Virus attachment protein p12 family RRM_1 PF00076.17 CDJ66362.1 - 7.4e-38 128.0 0.1 5.7e-18 64.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ66362.1 - 2.6e-34 117.0 0.0 1e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ66362.1 - 4.1e-20 71.3 0.0 1.2e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDJ66362.1 - 2.4e-05 23.9 0.0 0.028 14.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif FixQ PF05545.6 CDJ66363.1 - 0.024 14.2 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF418 PF04235.7 CDJ66363.1 - 0.052 13.2 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) IncA PF04156.9 CDJ66363.1 - 0.45 10.0 4.1 1.5 8.3 2.6 2.1 2 0 0 2 2 2 0 IncA protein DUF2681 PF10883.3 CDJ66363.1 - 4.9 7.4 7.8 26 5.1 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) AMP-binding PF00501.23 CDJ66364.1 - 1.5e-14 53.2 0.0 2.6e-14 52.4 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CDJ66365.1 - 1.1e-35 122.8 0.0 1.5e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDJ66365.1 - 0.0041 18.0 0.1 0.008 17.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain gag-asp_proteas PF13975.1 CDJ66366.1 - 0.078 12.8 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Utp13 PF08625.6 CDJ66368.1 - 3.1e-11 43.1 0.8 3.1e-11 43.1 0.5 2.7 2 1 2 4 4 4 1 Utp13 specific WD40 associated domain SprA-related PF12118.3 CDJ66368.1 - 0.0016 17.8 25.8 0.0016 17.8 17.9 3.1 3 0 0 3 3 3 1 SprA-related family Herpes_UL87 PF03043.9 CDJ66368.1 - 0.37 9.1 6.8 1 7.6 4.7 1.7 1 1 0 1 1 1 0 Herpesvirus UL87 family Hid1 PF12722.2 CDJ66368.1 - 0.56 7.8 17.5 0.053 11.1 8.6 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDJ66368.1 - 0.66 9.8 19.1 8.5 6.1 11.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 CDJ66368.1 - 1.4 8.5 28.5 4 7.0 13.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1510 PF07423.6 CDJ66368.1 - 2.3 7.5 21.4 0.19 11.0 10.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PIH1 PF08190.7 CDJ66368.1 - 2.3 7.5 24.2 9 5.6 12.6 2.4 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 DUF2052 PF09747.4 CDJ66368.1 - 3.9 7.3 30.0 0.76 9.6 12.4 2.5 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Allexi_40kDa PF05549.6 CDJ66368.1 - 5.2 6.2 12.7 0.72 9.0 4.7 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein ABC1 PF03109.11 CDJ66370.1 - 1.9e-33 114.9 0.7 3.7e-33 114.0 0.3 1.6 1 1 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CDJ66370.1 - 0.015 14.6 0.0 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 CDJ66370.1 - 0.21 11.2 3.7 0.36 10.5 0.1 2.8 2 2 1 3 3 3 0 Phosphotransferase enzyme family PAT1 PF09770.4 CDJ66371.1 - 0.012 13.9 27.5 0.014 13.7 19.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FNIP_N PF14636.1 CDJ66371.1 - 2.5 8.5 7.5 5 7.5 5.2 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF4175 PF13779.1 CDJ66371.1 - 9.6 3.7 39.6 16 2.9 27.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tim54 PF11711.3 CDJ66372.1 - 1.3 7.4 13.1 1.3 7.5 9.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Packaging_FI PF14000.1 CDJ66372.1 - 1.4 9.1 11.6 1.7 8.8 8.0 1.1 1 0 0 1 1 1 0 DNA packaging protein FI MRP-S31 PF15433.1 CDJ66372.1 - 4.5 6.5 26.8 4.7 6.5 18.6 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SeqA PF03925.8 CDJ66372.1 - 5.2 6.7 19.8 5.6 6.6 13.7 1.1 1 0 0 1 1 1 0 SeqA protein FYDLN_acid PF09538.5 CDJ66372.1 - 6.1 7.4 12.6 7.3 7.2 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Paf1 PF03985.8 CDJ66372.1 - 8.6 4.9 29.6 9.3 4.8 20.5 1.0 1 0 0 1 1 1 0 Paf1 Transketolase_C PF02780.15 CDJ66373.1 - 3.4e-12 46.3 0.0 3.4e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 CDJ66373.1 - 2.4e-06 27.1 0.0 2.4e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain PAT1 PF09770.4 CDJ66373.1 - 0.011 14.0 43.4 0.013 13.7 30.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M17_N PF02789.12 CDJ66373.1 - 2 8.1 16.8 0.8 9.4 6.4 3.1 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain eIF-3_zeta PF05091.7 CDJ66373.1 - 2.2 6.7 19.0 3 6.3 13.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1764 PF08576.5 CDJ66373.1 - 4.7 8.0 18.3 4.6 8.0 5.5 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) AAA_23 PF13476.1 CDJ66374.1 - 7 6.9 12.3 0.54 10.5 2.7 2.4 2 0 0 2 2 2 0 AAA domain SNAP PF14938.1 CDJ66375.1 - 0.13 11.3 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Ashwin PF15323.1 CDJ66376.1 - 0.2 11.6 22.9 0.31 11.0 15.9 1.3 1 0 0 1 1 1 0 Developmental protein DUF2146 PF10220.4 CDJ66376.1 - 9.3 4.0 11.3 12 3.7 7.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Tctex-1 PF03645.8 CDJ66377.1 - 2.3e-10 40.2 0.0 2.7e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Chorion_2 PF03964.10 CDJ66377.1 - 1.4 9.4 6.2 2.3 8.8 4.3 1.3 1 0 0 1 1 1 0 Chorion family 2 DUF4199 PF13858.1 CDJ66378.1 - 0.15 12.0 4.2 0.96 9.3 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Phage_int_SAM_5 PF13102.1 CDJ66378.1 - 6.2 6.8 11.5 5 7.1 0.0 2.3 2 0 0 2 2 2 0 Phage integrase SAM-like domain OATP PF03137.15 CDJ66378.1 - 9.9 4.0 7.9 2.4 6.1 3.1 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DGF-1_C PF11040.3 CDJ66380.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.2 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SOG2 PF10428.4 CDJ66380.1 - 0.17 10.5 0.0 0.17 10.5 0.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Macoilin PF09726.4 CDJ66380.1 - 6.8 4.8 10.0 8.1 4.5 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein TRA-1_regulated PF02343.11 CDJ66382.1 - 0.09 12.2 1.0 0.16 11.4 0.7 1.5 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 Cloacin PF03515.9 CDJ66382.1 - 0.13 11.4 7.8 0.21 10.7 5.4 1.3 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain SR-25 PF10500.4 CDJ66383.1 - 6e-05 22.6 13.2 0.0036 16.8 2.6 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Ham1p_like PF01725.11 CDJ66384.1 - 3.4e-23 82.0 0.0 6.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Ham1 family Spore_coat_CotO PF14153.1 CDJ66384.1 - 8.2e-06 25.3 0.4 1e-05 25.0 0.3 1.1 1 0 0 1 1 1 1 Spore coat protein CotO DDHD PF02862.12 CDJ66384.1 - 0.094 12.5 0.7 0.11 12.2 0.5 1.1 1 0 0 1 1 1 0 DDHD domain Ilar_coat PF01787.11 CDJ66384.1 - 0.1 12.1 2.5 0.13 11.8 1.7 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein Suf PF05843.9 CDJ66384.1 - 0.48 10.1 8.2 0.66 9.6 5.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ66384.1 - 0.91 7.6 15.8 1.1 7.3 11.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FCP1_C PF09309.5 CDJ66384.1 - 1.5 8.0 7.2 2.6 7.2 5.0 1.4 1 0 0 1 1 1 0 FCP1, C-terminal Pex14_N PF04695.8 CDJ66384.1 - 2.1 8.4 9.9 0.17 11.9 3.5 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Scs3p PF10261.4 CDJ66384.1 - 6.3 5.7 5.8 0.96 8.4 1.4 1.5 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Med15 PF09606.5 CDJ66384.1 - 7 4.7 26.6 9.8 4.2 18.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 CDJ66386.1 - 0.19 11.5 3.0 0.25 11.1 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Caldesmon PF02029.10 CDJ66386.1 - 0.39 9.0 8.2 0.5 8.7 5.7 1.1 1 0 0 1 1 1 0 Caldesmon Sporozoite_P67 PF05642.6 CDJ66386.1 - 3.1 5.5 12.7 3.5 5.3 8.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen APC_CDC26 PF10471.4 CDJ66386.1 - 6.6 7.5 12.7 12 6.6 8.8 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Conotoxin PF02950.12 CDJ66386.1 - 8 7.3 10.9 8.7 7.2 1.1 2.7 2 1 1 3 3 3 0 Conotoxin XPC-binding PF09280.6 CDJ66387.1 - 6e-21 73.6 8.4 6e-21 73.6 5.8 2.3 2 0 0 2 2 2 1 XPC-binding domain UBA PF00627.26 CDJ66387.1 - 7.5e-19 66.9 7.3 2.2e-10 40.0 0.1 2.9 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 CDJ66387.1 - 2.1e-06 27.0 0.0 2.1e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Dehydrin PF00257.14 CDJ66387.1 - 0.054 13.8 7.7 0.04 14.2 1.0 2.6 2 1 0 2 2 2 0 Dehydrin DUF2407 PF10302.4 CDJ66387.1 - 0.2 11.8 0.0 0.2 11.8 0.0 2.4 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain TBCA PF02970.11 CDJ66388.1 - 2e-19 69.4 4.0 2e-19 69.4 2.8 3.0 2 1 1 3 3 3 1 Tubulin binding cofactor A IL2 PF00715.12 CDJ66388.1 - 0.089 12.5 0.2 0.089 12.5 0.2 2.8 1 1 1 3 3 3 0 Interleukin 2 DDE_Tnp_1_2 PF13586.1 CDJ66388.1 - 4.7 7.4 8.8 14 5.9 0.2 3.3 3 0 0 3 3 3 0 Transposase DDE domain DUF4411 PF14367.1 CDJ66388.1 - 7.1 6.3 7.8 0.28 10.8 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4411) DHH PF01368.15 CDJ66389.1 - 3.1e-08 33.3 0.0 8.1e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 DHH family tRNA-synt_2b PF00587.20 CDJ66390.1 - 2.5e-43 147.6 0.0 6e-43 146.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) SR-25 PF10500.4 CDJ66390.1 - 0.002 17.6 24.3 0.002 17.6 16.8 6.5 4 2 2 6 6 6 1 Nuclear RNA-splicing-associated protein HGTP_anticodon PF03129.15 CDJ66392.1 - 1.6e-17 63.2 0.0 5.6e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain Pollen_Ole_e_I PF01190.12 CDJ66392.1 - 0.0097 15.7 1.8 0.019 14.8 1.3 1.4 1 0 0 1 1 1 1 Pollen proteins Ole e I like DNA_pol_viral_N PF00242.12 CDJ66392.1 - 0.025 13.6 7.9 0.034 13.1 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CDJ66392.1 - 0.11 10.7 12.1 0.14 10.4 8.4 1.1 1 0 0 1 1 1 0 Transmembrane protein GEMIN8 PF15348.1 CDJ66392.1 - 0.96 9.4 4.2 1.5 8.7 2.9 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 RAP1 PF07218.6 CDJ66392.1 - 2 6.4 19.3 2.6 6.0 13.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MRI PF15325.1 CDJ66392.1 - 5 8.1 8.9 9.7 7.2 6.2 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF1675 PF07897.6 CDJ66392.1 - 5.7 6.7 12.5 8.9 6.0 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Mcm10 PF09332.6 CDJ66392.1 - 7.3 5.8 10.6 11 5.2 7.4 1.2 1 0 0 1 1 1 0 Mcm10 replication factor mTERF PF02536.9 CDJ66393.1 - 1.3e-07 30.5 0.1 1.1e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 mTERF IF-2B PF01008.12 CDJ66394.1 - 2.1e-16 59.7 0.9 5.4e-16 58.4 0.0 2.1 2 1 0 2 2 2 1 Initiation factor 2 subunit family Spt20 PF12090.3 CDJ66394.1 - 0.017 14.4 0.0 0.017 14.4 0.0 3.8 2 2 1 3 3 3 0 Spt20 family PLRV_ORF5 PF01690.12 CDJ66394.1 - 1.1 8.3 32.3 0.22 10.6 18.0 2.0 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Herpes_env PF01673.13 CDJ66394.1 - 2.9 6.3 23.4 3.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein eIF-3_zeta PF05091.7 CDJ66394.1 - 3.6 6.0 26.4 3.5 6.1 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Utp14 PF04615.8 CDJ66394.1 - 4.9 5.1 33.0 0.47 8.5 16.1 2.2 2 0 0 2 2 2 0 Utp14 protein WD40 PF00400.27 CDJ66397.1 - 8.9e-17 60.2 0.0 1.3e-07 31.1 0.0 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Guanylate_cyc PF00211.15 CDJ66399.1 - 2.6e-20 72.5 0.1 4e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF572 PF04502.8 CDJ66401.1 - 2.4e-69 234.0 9.2 9.9e-69 232.0 6.4 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF572) Ribosomal_L11_N PF03946.9 CDJ66402.1 - 4.6e-22 77.2 0.1 6.7e-22 76.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CDJ66402.1 - 2.4e-08 34.0 0.2 0.0055 16.8 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein L11, RNA binding domain CobS PF02654.10 CDJ66403.1 - 0.0029 17.2 0.1 0.0053 16.3 0.1 1.3 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase Biotin_lipoyl PF00364.17 CDJ66404.1 - 3.1e-12 45.9 2.6 3.2e-12 45.9 1.1 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_2 PF12700.2 CDJ66404.1 - 0.00035 19.8 0.1 0.00061 19.0 0.0 1.3 1 0 0 1 1 1 1 HlyD family secretion protein DUF2638 PF10937.3 CDJ66404.1 - 0.0033 18.4 0.5 0.0033 18.4 0.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2638) Biotin_lipoyl_2 PF13533.1 CDJ66404.1 - 0.015 14.9 1.2 0.031 13.9 0.1 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like CENP-T PF15511.1 CDJ66405.1 - 0.68 9.1 9.8 0.91 8.7 6.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 CDJ66405.1 - 0.85 7.4 3.7 1.1 7.0 2.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 CDJ66405.1 - 2.9 7.9 7.5 4.4 7.3 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Rep_fac-A_C PF08646.5 CDJ66406.1 - 4.5e-10 39.4 0.1 8.6e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain DZR PF12773.2 CDJ66406.1 - 0.055 13.2 1.3 0.15 11.8 0.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon tRNA_anti-codon PF01336.20 CDJ66406.1 - 0.06 13.2 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SR-25 PF10500.4 CDJ66408.1 - 0.00069 19.1 5.5 0.00069 19.1 3.8 3.0 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Tau95 PF09734.4 CDJ66408.1 - 0.4 9.9 6.4 0.036 13.3 0.9 1.7 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit BOP1NT PF08145.7 CDJ66409.1 - 2.4e-25 89.7 7.5 2.8e-24 86.2 0.3 3.0 2 1 1 3 3 3 2 BOP1NT (NUC169) domain WD40 PF00400.27 CDJ66409.1 - 0.0064 16.3 0.6 2.3 8.2 0.9 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 CDJ66409.1 - 0.21 10.5 7.5 1.8 7.5 5.2 2.0 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Dala_Dala_lig_N PF01820.16 CDJ66409.1 - 0.27 11.5 3.6 0.12 12.7 0.6 1.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus CagX PF03524.10 CDJ66409.1 - 2.6 7.2 10.1 0.063 12.5 1.0 2.1 2 0 0 2 2 2 0 Conjugal transfer protein CAF-1_p150 PF11600.3 CDJ66409.1 - 5.2 6.3 30.2 0.017 14.5 8.9 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PcfK PF14058.1 CDJ66409.1 - 5.3 7.1 12.1 8.9 6.4 5.8 2.2 2 0 0 2 2 2 0 PcfK-like protein DUF3801 PF12687.2 CDJ66409.1 - 7.1 6.1 17.7 0.014 14.9 5.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) MIP-T3 PF10243.4 CDJ66410.1 - 0.039 12.4 73.4 0.049 12.1 50.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDJ66410.1 - 0.64 8.1 68.6 0.76 7.8 47.6 1.0 1 0 0 1 1 1 0 Utp14 protein PLRV_ORF5 PF01690.12 CDJ66410.1 - 1.4 7.9 51.2 1.6 7.7 35.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PAT1 PF09770.4 CDJ66410.1 - 9.9 4.2 139.1 13 3.9 96.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Shadoo PF14999.1 CDJ66411.1 - 0.0077 16.0 2.9 0.0077 16.0 2.0 3.4 3 1 0 3 3 3 1 Shadow of prion protein, neuroprotective DUF3617 PF12276.3 CDJ66411.1 - 0.16 11.4 9.2 0.25 10.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) PepSY_2 PF13670.1 CDJ66411.1 - 10 6.1 12.4 22 5.0 8.6 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain MutS_V PF00488.16 CDJ66412.1 - 2.5e-36 125.2 0.0 6.7e-36 123.8 0.0 1.7 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CDJ66412.1 - 1.1e-27 97.1 10.3 3.4e-27 95.5 7.2 1.8 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CDJ66412.1 - 5.3e-08 32.8 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CDJ66412.1 - 6.4e-07 29.4 0.1 1.2e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CDJ66412.1 - 1.5e-06 28.3 1.3 0.00059 19.9 0.0 3.1 2 1 0 2 2 2 1 MutS domain II SR-25 PF10500.4 CDJ66412.1 - 0.01 15.2 8.3 0.01 15.2 5.8 4.1 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein AAA_14 PF13173.1 CDJ66412.1 - 0.22 11.4 1.3 2.1 8.2 0.1 2.7 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 CDJ66412.1 - 0.99 9.6 0.0 0.99 9.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain ASFV_J13L PF05568.6 CDJ66412.1 - 1.1 8.7 11.6 2.4 7.6 8.0 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Cytochrom_C PF00034.16 CDJ66413.1 - 7.3e-05 23.5 1.1 0.0012 19.5 0.0 2.6 2 1 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CDJ66413.1 - 0.00042 20.4 0.0 0.00081 19.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III YscO PF07321.7 CDJ66413.1 - 0.0019 18.0 4.9 0.0025 17.6 3.4 1.1 1 0 0 1 1 1 1 Type III secretion protein YscO Cytochrom_C550 PF14495.1 CDJ66413.1 - 0.035 13.5 0.8 0.13 11.7 0.0 2.2 3 0 0 3 3 3 0 Cytochrome c-550 domain MMtag PF10159.4 CDJ66413.1 - 0.97 9.5 4.9 3.5 7.7 2.6 2.4 2 1 0 2 2 2 0 Kinase phosphorylation protein DUF2763 PF10961.3 CDJ66413.1 - 3.6 8.0 5.3 7.4 7.0 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) CLPTM1 PF05602.7 CDJ66414.1 - 4.9 5.7 10.5 5.5 5.5 7.3 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) SR-25 PF10500.4 CDJ66415.1 - 0.00012 21.6 6.8 0.00017 21.1 4.7 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ66415.1 - 5 6.4 9.0 6.8 6.0 6.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Corona_nucleoca PF00937.13 CDJ66415.1 - 6.2 5.6 7.5 8.9 5.1 5.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Tmemb_cc2 PF10267.4 CDJ66415.1 - 8 4.9 7.7 10 4.6 5.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TFIIA PF03153.8 CDJ66416.1 - 1.2 8.9 3.4 1.4 8.6 2.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 CDJ66418.1 - 0.049 12.8 9.4 0.055 12.7 6.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_LP PF03363.8 CDJ66418.1 - 0.084 12.4 1.4 0.17 11.4 1.0 1.5 1 0 0 1 1 1 0 Herpesvirus leader protein DUF566 PF04484.7 CDJ66418.1 - 8 5.8 8.5 3.1 7.2 4.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF566) Pex14_N PF04695.8 CDJ66419.1 - 0.039 13.9 9.6 0.053 13.5 6.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mcm10 PF09332.6 CDJ66419.1 - 1 8.5 11.2 1.4 8.1 7.7 1.3 1 0 0 1 1 1 0 Mcm10 replication factor Tfb2 PF03849.9 CDJ66420.1 - 7.6e-15 54.4 0.0 9.9e-15 54.0 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CDJ66420.1 - 0.00018 21.2 0.2 0.015 15.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1777 PF08648.7 CDJ66420.1 - 0.038 13.7 4.3 0.054 13.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1509 PF07420.6 CDJ66420.1 - 0.043 13.0 2.3 0.056 12.7 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PRP38_assoc PF12871.2 CDJ66420.1 - 0.95 10.0 11.0 1.5 9.4 7.6 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1418 PF07214.7 CDJ66421.1 - 0.14 11.8 1.2 0.18 11.4 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1418) DUF3402 PF11882.3 CDJ66421.1 - 0.93 8.4 5.4 0.97 8.4 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF494 PF04361.8 CDJ66421.1 - 1 9.0 6.7 1 8.9 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF494) GLTSCR1 PF15249.1 CDJ66421.1 - 3.5 7.7 10.0 6.7 6.8 7.0 1.6 1 1 0 1 1 1 0 Glioma tumor suppressor candidate region DUF2361 PF10153.4 CDJ66421.1 - 6 7.1 8.7 0.71 10.0 0.8 2.0 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2361) YebO PF13974.1 CDJ66422.1 - 0.1 12.4 5.8 0.15 11.8 4.0 1.3 1 1 0 1 1 1 0 YebO-like protein NOZZLE PF08744.5 CDJ66422.1 - 0.14 11.5 0.2 0.15 11.4 0.2 1.1 1 0 0 1 1 1 0 Plant transcription factor NOZZLE DUF4657 PF15552.1 CDJ66422.1 - 4.2 6.5 11.5 5.1 6.2 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) SNARE_assoc PF09335.6 CDJ66423.1 - 0.073 13.2 0.3 0.14 12.3 0.2 1.4 1 1 0 1 1 1 0 SNARE associated Golgi protein Secretin_N_2 PF07655.8 CDJ66423.1 - 0.49 10.8 7.6 0.16 12.3 1.0 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4658 PF15555.1 CDJ66423.1 - 0.67 9.8 6.9 1.1 9.0 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4658) RskA PF10099.4 CDJ66423.1 - 4.5 6.9 7.0 15 5.3 4.9 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA UCR_Fe-S_N PF10399.4 CDJ66423.1 - 5.2 6.3 7.8 3 7.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Med15 PF09606.5 CDJ66424.1 - 9.3 4.3 65.3 0.096 10.8 9.4 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF384 PF04064.8 CDJ66425.1 - 9.2e-11 41.1 0.1 1.8e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF2201_N PF13203.1 CDJ66425.1 - 0.0049 16.0 7.6 0.0049 16.0 5.3 2.1 2 0 0 2 2 2 1 Putative metallopeptidase domain Zip PF02535.17 CDJ66425.1 - 0.053 12.5 0.1 0.053 12.5 0.1 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter FimP PF09766.4 CDJ66425.1 - 0.095 11.7 29.0 0.14 11.2 8.9 2.2 2 0 0 2 2 2 0 Fms-interacting protein DUF912 PF06024.7 CDJ66425.1 - 0.5 10.4 13.0 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4463 PF14703.1 CDJ66425.1 - 2.6 8.5 5.5 0.85 10.1 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DUF4512 PF14975.1 CDJ66425.1 - 4.3 8.2 8.6 0.88 10.4 2.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) TRAP_alpha PF03896.11 CDJ66425.1 - 7 5.5 8.1 1.2 8.1 1.6 2.1 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_60s PF00428.14 CDJ66425.1 - 7.6 7.0 16.5 0.23 11.8 5.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein MRP-S25 PF13741.1 CDJ66426.1 - 0.0059 16.1 0.0 0.0065 15.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 Sporozoite_P67 PF05642.6 CDJ66426.1 - 1.8 6.3 12.1 2 6.1 8.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sel1 PF08238.7 CDJ66427.1 - 8.6e-06 26.2 1.4 0.00011 22.6 0.2 3.7 4 0 0 4 4 4 2 Sel1 repeat DUF3138 PF11336.3 CDJ66427.1 - 1.2 7.1 10.0 1.5 6.9 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HSP20 PF00011.16 CDJ66428.1 - 2.2e-10 40.3 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Ribosomal_60s PF00428.14 CDJ66428.1 - 0.0029 17.9 6.6 0.0029 17.9 4.5 1.5 2 0 0 2 2 2 1 60s Acidic ribosomal protein RskA PF10099.4 CDJ66428.1 - 0.028 14.1 0.7 0.038 13.7 0.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3628 PF12300.3 CDJ66428.1 - 0.048 13.6 2.4 0.06 13.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) PepSY_2 PF13670.1 CDJ66428.1 - 0.11 12.3 5.5 0.17 11.7 3.8 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF2573 PF10835.3 CDJ66429.1 - 0.019 14.9 0.4 0.02 14.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) MttA_Hcf106 PF02416.11 CDJ66429.1 - 0.4 9.8 2.3 0.47 9.6 1.5 1.3 1 1 0 1 1 1 0 mttA/Hcf106 family DUF3682 PF12446.3 CDJ66429.1 - 5.5 7.2 7.8 5.7 7.2 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) GAGA_bind PF06217.7 CDJ66430.1 - 1.6 8.6 13.1 6.7 6.5 3.4 2.6 2 1 0 2 2 2 0 GAGA binding protein-like family TPT PF03151.11 CDJ66431.1 - 1e-15 57.6 18.3 7.4e-12 45.1 3.6 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CDJ66431.1 - 0.002 17.1 8.2 0.019 13.9 0.5 2.9 2 1 1 3 3 3 2 UAA transporter family EamA PF00892.15 CDJ66431.1 - 0.0039 17.2 18.0 0.017 15.1 7.0 3.2 3 1 0 3 3 3 2 EamA-like transporter family DUF1517 PF07466.6 CDJ66431.1 - 0.087 11.7 7.0 0.2 10.6 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Myco_19_kDa PF05481.7 CDJ66431.1 - 2.6 7.8 9.7 7.4 6.3 6.7 1.8 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen SAGA-Tad1 PF12767.2 CDJ66432.1 - 0.4 10.3 24.0 0.76 9.3 16.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ELL PF10390.4 CDJ66434.1 - 0.097 11.8 0.5 0.14 11.3 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL FKBP_C PF00254.23 CDJ66435.1 - 3e-23 81.6 0.0 4.5e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glucan_synthase PF02364.10 CDJ66437.1 - 7e-85 285.5 17.6 2.4e-56 191.1 9.1 4.0 3 1 1 4 4 4 3 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CDJ66437.1 - 1.1e-17 63.9 1.8 3.5e-17 62.4 1.2 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Vezatin PF12632.2 CDJ66438.1 - 0.045 12.8 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes Ribonuc_red_lgC PF02867.10 CDJ66441.1 - 0.073 11.6 0.8 0.11 11.0 0.6 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain IncA PF04156.9 CDJ66441.1 - 1 8.9 28.1 1.4 8.4 3.8 3.3 3 0 0 3 3 3 0 IncA protein CHORD PF04968.7 CDJ66442.1 - 2.1e-13 50.2 9.7 1.4e-09 37.9 0.1 2.5 2 0 0 2 2 2 2 CHORD SOBP PF15279.1 CDJ66442.1 - 0.48 10.7 13.4 0.62 10.3 9.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein THRAP3_BCLAF1 PF15440.1 CDJ66442.1 - 0.79 8.3 15.2 1 7.9 10.5 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF4179 PF13786.1 CDJ66442.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4179) CytochromB561_N PF09786.4 CDJ66442.1 - 4.8 5.5 12.1 5.5 5.3 8.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Herpes_env PF01673.13 CDJ66443.1 - 0.73 8.3 4.3 0.86 8.0 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SR-25 PF10500.4 CDJ66443.1 - 1.6 8.1 6.0 0.62 9.5 0.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peripla_BP_3 PF13377.1 CDJ66443.1 - 8.4 6.3 17.1 11 5.9 11.9 1.1 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Spore_YhcN_YlaJ PF09580.5 CDJ66444.1 - 0.019 15.0 1.7 0.024 14.7 1.2 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Mcp5_PH PF12814.2 CDJ66444.1 - 0.039 13.8 2.3 0.069 13.0 0.8 2.1 1 1 1 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology BAF1_ABF1 PF04684.8 CDJ66444.1 - 0.24 10.2 14.9 0.25 10.1 10.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor N_NLPC_P60 PF12912.2 CDJ66444.1 - 0.25 11.4 8.3 0.43 10.6 5.8 1.4 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term DUF4609 PF15382.1 CDJ66444.1 - 1 9.1 6.3 0.72 9.6 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) DUF4175 PF13779.1 CDJ66444.1 - 1.2 6.7 21.6 1.5 6.3 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDJ66444.1 - 1.2 7.2 19.6 1.3 7.1 13.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDJ66444.1 - 2.6 7.7 9.0 2.9 7.5 6.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ66444.1 - 4.6 6.2 12.9 6.2 5.7 9.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 CDJ66444.1 - 5.9 4.9 25.4 6.1 4.8 17.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 CDJ66444.1 - 6.7 6.4 13.4 8.1 6.2 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Nucleo_P87 PF07267.6 CDJ66444.1 - 7.3 5.1 8.1 8.5 4.9 5.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spt20 PF12090.3 CDJ66444.1 - 9.6 5.5 9.6 13 5.0 6.7 1.2 1 0 0 1 1 1 0 Spt20 family PAM2 PF07145.10 CDJ66445.1 - 0.026 14.0 1.7 0.051 13.0 1.2 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Zein PF01559.11 CDJ66446.1 - 0.04 13.1 10.3 0.048 12.9 7.1 1.1 1 0 0 1 1 1 0 Zein seed storage protein AUX_IAA PF02309.11 CDJ66446.1 - 0.54 9.9 4.3 0.6 9.8 3.0 1.1 1 0 0 1 1 1 0 AUX/IAA family bZIP_Maf PF03131.12 CDJ66446.1 - 0.6 10.4 5.3 1.1 9.5 3.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor RRM_6 PF14259.1 CDJ66449.1 - 7e-05 22.7 0.0 0.001 19.0 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ66449.1 - 0.00036 20.1 0.0 0.34 10.5 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ66449.1 - 0.00092 19.0 0.3 0.015 15.1 0.2 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnd1_N PF12922.2 CDJ66449.1 - 0.0031 17.1 7.0 0.0031 17.1 4.8 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term SR-25 PF10500.4 CDJ66449.1 - 0.0039 16.7 13.2 0.0039 16.7 9.2 2.7 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2407_C PF13373.1 CDJ66449.1 - 0.046 13.6 5.7 0.057 13.3 0.0 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain Trypan_glycop_C PF10659.4 CDJ66449.1 - 2.5 8.4 9.4 0.61 10.4 3.9 2.0 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain Neur_chan_memb PF02932.11 CDJ66449.1 - 5.3 6.8 11.3 4.8 6.9 5.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PP2C PF00481.16 CDJ66452.1 - 1.9e-17 63.4 0.8 1.9e-17 63.4 0.5 4.2 3 2 1 4 4 4 2 Protein phosphatase 2C SR-25 PF10500.4 CDJ66452.1 - 7.6e-07 28.8 13.3 7.6e-07 28.8 9.3 7.9 3 1 3 7 7 7 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDJ66452.1 - 0.00044 18.6 11.2 0.00044 18.6 7.8 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDJ66452.1 - 0.023 15.0 0.4 0.023 15.0 0.3 2.6 2 1 0 2 2 2 0 AAA domain DUF2371 PF10177.4 CDJ66452.1 - 0.032 14.1 0.0 0.032 14.1 0.0 4.0 5 1 0 5 5 5 0 Uncharacterised conserved protein (DUF2371) Pox_A12 PF04651.8 CDJ66454.1 - 0.059 13.4 1.9 0.07 13.2 1.3 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein CDK2AP PF09806.4 CDJ66454.1 - 0.094 12.9 6.9 0.11 12.7 4.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDJ66454.1 - 0.16 12.3 7.2 0.22 11.9 5.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med15 PF09606.5 CDJ66455.1 - 0.06 11.5 38.6 0.014 13.6 7.1 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0697 PF15117.1 CDJ66455.1 - 0.097 12.4 0.1 0.097 12.4 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0697 FAM101 PF15068.1 CDJ66455.1 - 0.25 10.7 7.8 0.12 11.8 1.6 2.3 2 0 0 2 2 2 0 FAM101 family Dehydrin PF00257.14 CDJ66455.1 - 1.4 9.1 17.5 1.3 9.3 0.3 2.4 1 1 1 2 2 2 0 Dehydrin Macoilin PF09726.4 CDJ66455.1 - 3 6.0 23.8 0.0048 15.2 3.6 2.1 2 0 0 2 2 2 0 Transmembrane protein HEAT PF02985.17 CDJ66456.1 - 2.7e-08 33.2 11.5 0.0013 18.6 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat Neur_chan_memb PF02932.11 CDJ66456.1 - 0.0072 16.2 5.7 11 5.8 6.2 2.5 2 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.3 CDJ66456.1 - 0.17 11.2 0.0 0.17 11.2 0.0 3.3 2 1 0 2 2 2 0 Spt20 family Plasmodium_Vir PF05795.6 CDJ66456.1 - 4 6.5 8.0 16 4.5 4.3 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SAPS PF04499.10 CDJ66456.1 - 4.2 5.8 16.3 85 1.5 10.7 2.7 1 1 1 2 2 2 0 SIT4 phosphatase-associated protein Aminotran_1_2 PF00155.16 CDJ66457.1 - 4.6e-07 29.1 0.0 4.6e-07 29.1 0.0 2.5 2 1 0 2 2 1 1 Aminotransferase class I and II Activator_LAG-3 PF11498.3 CDJ66457.1 - 9.5e-06 24.6 44.6 1.1e-05 24.3 30.9 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Med15 PF09606.5 CDJ66457.1 - 1.1e-05 23.9 33.3 1.1e-05 23.8 23.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDJ66457.1 - 0.011 16.1 9.6 0.014 15.8 6.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CRT10 PF08728.5 CDJ66457.1 - 0.033 12.1 1.9 0.034 12.1 1.3 1.0 1 0 0 1 1 1 0 CRT10 PAT1 PF09770.4 CDJ66457.1 - 0.061 11.5 33.9 0.073 11.3 23.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF972 PF06156.8 CDJ66457.1 - 0.14 12.5 17.3 0.21 11.9 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Exonuc_VII_L PF02601.10 CDJ66457.1 - 0.22 10.6 15.3 0.28 10.3 10.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.9 CDJ66457.1 - 0.25 9.8 34.9 0.36 9.3 24.2 1.2 1 0 0 1 1 1 0 HemX Neur_chan_memb PF02932.11 CDJ66457.1 - 0.3 10.9 5.7 0.34 10.7 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_UL87 PF03043.9 CDJ66457.1 - 0.34 9.2 4.6 0.36 9.1 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family V_ATPase_I PF01496.14 CDJ66457.1 - 0.35 8.6 12.4 0.42 8.4 8.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.12 CDJ66457.1 - 0.4 9.4 6.2 0.52 9.0 4.3 1.1 1 0 0 1 1 1 0 Presenilin DUF342 PF03961.8 CDJ66457.1 - 0.46 8.8 9.7 0.54 8.6 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Suf PF05843.9 CDJ66457.1 - 0.47 10.1 15.2 0.69 9.5 10.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HlyD_2 PF12700.2 CDJ66457.1 - 0.49 9.5 9.3 0.51 9.4 6.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein TFIIA PF03153.8 CDJ66457.1 - 0.51 10.1 25.2 0.7 9.7 17.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APG6 PF04111.7 CDJ66457.1 - 0.54 9.2 22.8 0.71 8.8 15.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Ribosomal_60s PF00428.14 CDJ66457.1 - 0.59 10.5 15.8 0.087 13.2 7.9 1.8 2 0 0 2 2 1 0 60s Acidic ribosomal protein DUF3450 PF11932.3 CDJ66457.1 - 0.96 8.6 35.2 1.6 7.9 24.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Acyl-thio_N PF12590.3 CDJ66457.1 - 1.5 9.2 7.8 2.5 8.5 5.4 1.3 1 0 0 1 1 1 0 Acyl-ATP thioesterase Peptidase_S49_N PF08496.5 CDJ66457.1 - 2.1 8.0 13.3 3.1 7.5 9.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_S15 PF02129.13 CDJ66457.1 - 2.4 7.4 10.4 3.3 7.0 7.2 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DOR PF14839.1 CDJ66457.1 - 3.7 7.2 25.3 5.6 6.6 17.6 1.2 1 0 0 1 1 1 0 DOR family TALPID3 PF15324.1 CDJ66457.1 - 4.9 4.3 27.7 5.8 4.1 19.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target FUSC PF04632.7 CDJ66457.1 - 5.8 5.2 22.4 6.7 5.0 15.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Serinc PF03348.10 CDJ66457.1 - 5.9 5.4 6.6 8.9 4.8 4.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) PBP_sp32 PF07222.7 CDJ66457.1 - 7.2 5.7 16.8 10 5.2 11.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SF3a60_bindingd PF12108.3 CDJ66458.1 - 2.3e-05 23.8 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Chorion_2 PF03964.10 CDJ66458.1 - 0.018 15.6 0.1 0.028 14.9 0.1 1.3 1 0 0 1 1 1 0 Chorion family 2 Methyltransf_30 PF05430.6 CDJ66458.1 - 0.1 12.2 0.1 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase DUF3186 PF11382.3 CDJ66458.1 - 0.27 10.3 2.8 0.37 9.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Tom37_C PF11801.3 CDJ66458.1 - 0.57 10.0 6.3 0.77 9.5 4.3 1.4 1 1 0 1 1 1 0 Tom37 C-terminal domain DUF3530 PF12048.3 CDJ66458.1 - 1.4 7.8 11.7 0.36 9.7 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) HEV_ORF1 PF02444.11 CDJ66459.1 - 0.035 14.2 0.4 0.073 13.2 0.3 1.6 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) RskA PF10099.4 CDJ66459.1 - 0.31 10.7 16.3 1.2 8.8 11.3 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FAM60A PF15396.1 CDJ66459.1 - 1.1 9.0 5.3 1.4 8.5 3.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Med15 PF09606.5 CDJ66459.1 - 1.1 7.3 27.8 1.5 6.8 19.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ66459.1 - 1.3 7.1 24.4 1.4 7.0 16.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDJ66459.1 - 1.7 8.4 8.4 2.5 7.8 5.8 1.3 1 0 0 1 1 1 0 DDHD domain Membralin PF09746.4 CDJ66459.1 - 4.1 6.3 4.8 6.6 5.6 3.3 1.2 1 1 0 1 1 1 0 Tumour-associated protein FANCI_S4 PF14678.1 CDJ66459.1 - 4.5 6.3 7.9 0.36 9.8 0.4 2.1 1 1 1 2 2 2 0 FANCI solenoid 4 Hid1 PF12722.2 CDJ66459.1 - 5.1 4.6 11.1 5.9 4.4 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Proteasom_PSMB PF10508.4 CDJ66460.1 - 1.8e-22 79.2 2.4 8.5e-22 77.0 1.7 1.8 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit CCER1 PF15482.1 CDJ66461.1 - 0.019 14.6 1.3 0.051 13.1 0.9 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Corona_S2 PF01601.11 CDJ66461.1 - 0.029 12.4 2.1 0.039 12.0 1.5 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Prominin PF05478.6 CDJ66461.1 - 0.1 10.1 1.2 0.14 9.6 0.8 1.1 1 0 0 1 1 1 0 Prominin Peptidase_M16_C PF05193.16 CDJ66462.1 - 8.1e-35 120.1 0.0 2e-34 118.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CDJ66462.1 - 4.4e-27 94.6 0.0 1.3e-26 93.1 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PIGA PF08288.7 CDJ66462.1 - 0.055 13.8 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 PIGA (GPI anchor biosynthesis) Orai-1 PF07856.7 CDJ66463.1 - 0.00048 19.7 8.2 0.025 14.1 0.1 2.1 2 0 0 2 2 2 2 Mediator of CRAC channel activity DUF872 PF05915.7 CDJ66463.1 - 0.3 10.9 1.7 0.91 9.4 1.2 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) MFS_1 PF07690.11 CDJ66464.1 - 3.8e-20 71.9 38.4 1.3e-18 66.9 4.1 3.9 4 1 1 5 5 5 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CDJ66464.1 - 1.7e-12 46.7 23.6 2.6e-12 46.0 1.1 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 CDJ66464.1 - 0.0042 15.2 27.5 0.16 9.9 3.3 4.9 4 1 1 5 5 5 3 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.3 CDJ66464.1 - 0.044 13.1 3.4 0.12 11.6 2.3 1.8 1 0 0 1 1 1 0 Spt20 family Macoilin PF09726.4 CDJ66464.1 - 0.35 9.0 6.7 0.013 13.7 0.4 1.7 2 0 0 2 2 2 0 Transmembrane protein FimP PF09766.4 CDJ66464.1 - 0.94 8.4 10.1 2.6 7.0 7.0 1.7 1 0 0 1 1 1 0 Fms-interacting protein GH114_assoc PF14741.1 CDJ66465.1 - 0.056 13.1 0.0 0.064 12.9 0.0 1.1 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain AP2 PF00847.15 CDJ66466.1 - 1.6e-17 63.3 1.9 2.6e-08 33.9 0.1 8.5 11 0 0 11 11 11 3 AP2 domain Peptidase_M50 PF02163.17 CDJ66467.1 - 0.22 10.4 0.1 3 6.7 0.0 2.5 2 1 0 2 2 2 0 Peptidase family M50 TGT PF01702.13 CDJ66468.1 - 1.1e-10 41.2 0.0 2.8e-09 36.6 0.1 2.3 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Ribosomal_L7Ae PF01248.21 CDJ66469.1 - 2.8e-25 87.6 0.3 3.5e-25 87.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CDJ66469.1 - 0.054 13.3 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 CDJ66469.1 - 0.15 11.8 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain PDEase_I PF00233.14 CDJ66472.1 - 1.5e-38 132.9 4.9 2.3e-38 132.2 3.4 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Suf PF05843.9 CDJ66472.1 - 0.081 12.6 2.4 0.13 11.9 1.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ66472.1 - 0.12 11.3 7.0 0.2 10.6 4.8 1.3 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDJ66472.1 - 0.44 9.8 3.8 0.87 8.9 2.7 1.4 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.3 CDJ66472.1 - 4.5 5.9 29.9 8.5 5.0 20.8 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDJ66472.1 - 8.8 4.3 36.8 13 3.8 25.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MCR_alpha PF02249.12 CDJ66473.1 - 0.054 13.5 2.8 0.15 12.1 1.9 1.7 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain HAUS-augmin3 PF14932.1 CDJ66473.1 - 1.5 7.9 11.0 0.3 10.2 4.8 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 ABC2_membrane_2 PF12679.2 CDJ66473.1 - 2.6 6.8 4.8 3.9 6.2 3.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1183 PF06682.7 CDJ66473.1 - 3.7 7.0 7.8 5.6 6.4 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) GLTSCR1 PF15249.1 CDJ66473.1 - 4.7 7.3 7.0 0.78 9.8 0.1 2.5 2 1 0 2 2 2 0 Glioma tumor suppressor candidate region SR-25 PF10500.4 CDJ66473.1 - 4.8 6.5 31.8 1 8.7 17.5 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein YicC_N PF03755.8 CDJ66473.1 - 8.4 6.3 12.0 8.2 6.3 5.7 2.0 2 0 0 2 2 2 0 YicC-like family, N-terminal region RskA PF10099.4 CDJ66474.1 - 0.015 15.0 13.2 0.61 9.8 4.6 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA ketoacyl-synt PF00109.21 CDJ66475.1 - 3.8e-79 265.7 0.1 1.7e-78 263.5 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CDJ66475.1 - 3.8e-63 212.4 0.3 4.5e-52 176.3 0.0 3.1 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 CDJ66475.1 - 9.1e-52 175.3 0.7 7.2e-40 136.6 0.0 3.5 4 0 0 4 4 4 2 short chain dehydrogenase Acyl_transf_1 PF00698.16 CDJ66475.1 - 3.1e-51 174.6 0.0 5.9e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 CDJ66475.1 - 3.2e-44 151.2 2.0 5.3e-44 150.5 1.4 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 CDJ66475.1 - 2.4e-40 137.0 0.8 6.6e-40 135.6 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 CDJ66475.1 - 9.9e-19 67.1 0.0 2.4e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 CDJ66475.1 - 6.1e-14 52.0 0.0 1.6e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 CDJ66475.1 - 1.4e-09 38.9 0.2 1.5e-08 35.5 0.0 3.1 4 0 0 4 4 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDJ66475.1 - 1.3e-07 31.3 4.4 1.9e-06 27.5 0.2 3.4 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 CDJ66475.1 - 0.0031 16.5 0.1 0.0076 15.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 CDJ66475.1 - 0.0051 16.2 0.0 0.12 11.7 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDJ66475.1 - 0.092 11.4 0.0 0.35 9.5 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family MitMem_reg PF13012.1 CDJ66476.1 - 1.6e-22 79.7 0.2 1.6e-22 79.7 0.2 3.0 2 1 1 3 3 1 1 Maintenance of mitochondrial structure and function Pex14_N PF04695.8 CDJ66476.1 - 7.4e-05 22.8 10.0 7.4e-05 22.8 7.0 2.6 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CDJ66476.1 - 0.00011 20.7 59.0 0.0016 16.7 19.8 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 UPF0564 PF10595.4 CDJ66476.1 - 0.00035 19.6 16.6 0.00035 19.6 11.5 2.3 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 DUF4557 PF15101.1 CDJ66476.1 - 0.0052 16.6 21.5 0.0052 16.6 14.9 2.9 2 1 0 2 2 1 1 Domain of unknown function (DUF4557) SprA-related PF12118.3 CDJ66476.1 - 0.026 13.8 69.5 0.017 14.4 15.4 2.1 2 0 0 2 2 2 0 SprA-related family DUF605 PF04652.11 CDJ66476.1 - 0.33 10.3 42.3 0.14 11.5 12.2 2.1 2 0 0 2 2 2 0 Vta1 like DUF1510 PF07423.6 CDJ66476.1 - 0.34 10.2 36.6 1.2 8.4 9.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Med15 PF09606.5 CDJ66476.1 - 0.44 8.6 89.7 0.012 13.8 31.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 CDJ66476.1 - 0.71 9.7 29.8 0.27 11.1 5.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CDJ66476.1 - 0.79 9.5 35.0 0.75 9.6 9.3 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Gag_spuma PF03276.9 CDJ66476.1 - 1 7.6 50.3 0.23 9.7 17.1 2.1 2 0 0 2 2 2 0 Spumavirus gag protein Zip PF02535.17 CDJ66476.1 - 1.2 8.1 12.6 1.7 7.5 0.8 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Spore_YhcN_YlaJ PF09580.5 CDJ66476.1 - 1.4 9.0 26.2 0.093 12.8 6.0 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF4175 PF13779.1 CDJ66476.1 - 1.4 6.5 79.0 0.028 12.1 27.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) TT_ORF1 PF02956.9 CDJ66476.1 - 2.8 6.2 22.5 0.16 10.3 4.8 2.1 2 0 0 2 2 2 0 TT viral orf 1 HCO3_cotransp PF00955.16 CDJ66476.1 - 3.6 6.1 12.6 0.34 9.4 1.4 2.1 2 0 0 2 2 2 0 HCO3- transporter family COX14 PF14880.1 CDJ66476.1 - 3.7 7.2 0.0 3.7 7.2 0.0 5.4 3 2 0 3 3 1 0 Cytochrome oxidase c assembly FAM60A PF15396.1 CDJ66476.1 - 8.5 6.0 33.5 0.36 10.5 6.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Band_3_cyto PF07565.8 CDJ66476.1 - 9.9 5.5 36.6 0.62 9.5 8.5 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain HSP70 PF00012.15 CDJ66477.1 - 5.2e-21 74.2 0.1 4.3e-20 71.1 0.0 1.9 1 1 1 2 2 2 1 Hsp70 protein Med15 PF09606.5 CDJ66477.1 - 0.027 12.6 11.9 0.036 12.2 8.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDJ66477.1 - 0.071 12.0 2.0 0.1 11.5 1.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TMEM223 PF14640.1 CDJ66477.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 FimP PF09766.4 CDJ66477.1 - 0.74 8.8 8.5 1.2 8.1 5.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein Activator_LAG-3 PF11498.3 CDJ66477.1 - 0.78 8.4 16.6 1.1 7.8 11.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DivIC PF04977.10 CDJ66477.1 - 1.5 8.3 7.6 2.8 7.4 5.3 1.4 1 0 0 1 1 1 0 Septum formation initiator CTP_transf_1 PF01148.15 CDJ66478.1 - 4.3e-06 26.5 1.3 6.4e-06 26.0 0.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Potyvirid-P3 PF13608.1 CDJ66478.1 - 0.00098 18.3 0.4 0.00098 18.3 0.3 2.1 2 0 0 2 2 2 1 Protein P3 of Potyviral polyprotein CD20 PF04103.10 CDJ66478.1 - 0.0032 17.4 4.1 0.25 11.2 0.2 3.1 2 1 0 2 2 2 2 CD20-like family FA_desaturase PF00487.19 CDJ66478.1 - 0.0049 16.3 1.3 0.048 13.0 1.3 2.1 2 0 0 2 2 2 1 Fatty acid desaturase IncA PF04156.9 CDJ66478.1 - 0.019 14.5 4.6 0.019 14.5 3.2 4.1 3 2 1 4 4 2 0 IncA protein Tetraspannin PF00335.15 CDJ66478.1 - 0.1 11.8 2.3 5.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Tetraspanin family Pex24p PF06398.6 CDJ66478.1 - 0.12 11.1 0.2 0.36 9.5 0.0 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin OSTbeta PF15048.1 CDJ66478.1 - 0.22 11.5 6.0 0.43 10.6 0.1 2.6 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein FHIPEP PF00771.15 CDJ66478.1 - 0.37 9.0 10.5 0.039 12.2 1.5 2.2 2 0 0 2 2 2 0 FHIPEP family YfhO PF09586.5 CDJ66478.1 - 1 7.2 6.8 0.088 10.8 0.7 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO OAD_gamma PF04277.8 CDJ66478.1 - 1.4 9.3 0.0 1.4 9.3 0.0 4.5 5 0 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain FPN1 PF06963.7 CDJ66478.1 - 6.3 5.0 8.9 0.19 10.0 0.3 2.2 2 0 0 2 2 2 0 Ferroportin1 (FPN1) DUF4598 PF15370.1 CDJ66479.1 - 0.085 13.1 0.4 0.085 13.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) DUF4366 PF14283.1 CDJ66479.1 - 0.11 11.8 4.6 0.13 11.6 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SDF PF00375.13 CDJ66479.1 - 0.15 10.8 0.6 1 8.0 0.0 1.9 1 1 1 2 2 2 0 Sodium:dicarboxylate symporter family Trp_oprn_chp PF09534.5 CDJ66479.1 - 0.95 9.0 9.5 1.8 8.1 6.6 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CD20 PF04103.10 CDJ66479.1 - 1.1 9.1 11.9 0.3 11.0 0.2 2.1 1 1 1 2 2 2 0 CD20-like family RskA PF10099.4 CDJ66479.1 - 1.1 8.9 23.1 4.7 6.9 5.8 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3824 PF12868.2 CDJ66479.1 - 1.4 9.8 8.0 1.8 9.5 0.9 2.1 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Peptidase_C6 PF00851.13 CDJ66479.1 - 1.5 7.3 17.9 1.8 7.0 12.4 1.1 1 0 0 1 1 1 0 Helper component proteinase SAGA-Tad1 PF12767.2 CDJ66479.1 - 2.9 7.4 21.0 3.5 7.2 14.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3408 PF11888.3 CDJ66479.1 - 4.5 7.2 11.5 1.8 8.5 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) eIF_4EBP PF05456.6 CDJ66479.1 - 4.8 6.9 11.0 1.7 8.3 2.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Neur_chan_memb PF02932.11 CDJ66479.1 - 5.3 6.8 10.2 7.1 6.4 7.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PEX11 PF05648.9 CDJ66479.1 - 6.2 6.0 15.7 2.4 7.3 0.4 2.1 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Hid1 PF12722.2 CDJ66479.1 - 7.3 4.1 15.5 7.6 4.0 10.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cellulose_synt PF03552.9 CDJ66479.1 - 9.9 4.3 6.8 12 4.0 4.7 1.2 1 0 0 1 1 1 0 Cellulose synthase SR-25 PF10500.4 CDJ66480.1 - 0.014 14.9 6.0 0.014 14.9 4.1 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 CDJ66480.1 - 0.036 14.2 8.2 0.12 12.5 5.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) MIP-T3 PF10243.4 CDJ66481.1 - 8.8e-08 31.0 54.7 1.3e-07 30.5 37.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF3792 PF12670.2 CDJ66481.1 - 0.025 14.4 0.5 0.025 14.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Daxx PF03344.10 CDJ66481.1 - 8.5 4.7 61.5 12 4.1 42.6 1.2 1 0 0 1 1 1 0 Daxx Family Fer2 PF00111.22 CDJ66482.1 - 5.3e-20 70.9 1.6 1.5e-19 69.4 1.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 CDJ66482.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TFIIA PF03153.8 CDJ66482.1 - 0.029 14.2 11.6 0.033 14.0 8.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ66482.1 - 4.7 5.3 27.5 5.9 5.0 19.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ICAP-1_inte_bdg PF10480.4 CDJ66483.1 - 0.0071 16.1 0.1 0.0091 15.7 0.0 1.1 1 0 0 1 1 1 1 Beta-1 integrin binding protein SR-25 PF10500.4 CDJ66483.1 - 0.44 9.9 4.2 0.72 9.2 2.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.4 CDJ66484.1 - 0.013 15.1 3.6 0.019 14.7 2.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3446 PF11928.3 CDJ66484.1 - 0.66 10.2 12.1 0.56 10.4 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) IncA PF04156.9 CDJ66484.1 - 3.4 7.2 11.7 0.067 12.7 2.4 1.9 1 1 1 2 2 2 0 IncA protein SR-25 PF10500.4 CDJ66484.1 - 4.2 6.7 13.7 0.77 9.1 6.9 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein YajC PF02699.10 CDJ66484.1 - 7.9 6.2 5.6 12 5.6 0.7 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit ATP_bind_1 PF03029.12 CDJ66486.1 - 5.8e-09 35.8 0.0 0.00096 18.7 0.0 2.2 1 1 0 2 2 2 2 Conserved hypothetical ATP binding protein DUF4094 PF13334.1 CDJ66487.1 - 0.0072 16.6 0.7 0.015 15.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) DUF3681 PF12442.3 CDJ66487.1 - 0.013 15.7 0.9 0.046 13.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) OSTbeta PF15048.1 CDJ66487.1 - 0.013 15.6 0.4 0.02 14.9 0.3 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein FHIPEP PF00771.15 CDJ66487.1 - 0.028 12.7 0.3 0.04 12.2 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family FAM176 PF14851.1 CDJ66487.1 - 0.029 14.0 0.1 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.10 CDJ66487.1 - 0.077 13.0 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF1191 PF06697.7 CDJ66487.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF1275 PF06912.6 CDJ66487.1 - 0.12 11.5 1.9 0.47 9.6 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) ASFV_J13L PF05568.6 CDJ66487.1 - 0.13 11.7 3.5 0.59 9.6 1.0 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein TMEM51 PF15345.1 CDJ66487.1 - 0.15 11.7 4.5 0.28 10.8 3.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF788 PF05620.6 CDJ66487.1 - 0.33 10.7 2.7 0.53 10.1 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) 60KD_IMP PF02096.15 CDJ66487.1 - 0.49 10.0 4.5 0.77 9.3 3.1 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein DUF4557 PF15101.1 CDJ66487.1 - 6 6.6 11.7 7.9 6.2 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) YfhO PF09586.5 CDJ66488.1 - 0.0011 17.0 0.7 0.0018 16.4 0.5 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO ABC2_membrane_2 PF12679.2 CDJ66488.1 - 0.028 13.2 0.3 0.076 11.8 0.2 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein CotH PF08757.6 CDJ66488.1 - 0.11 11.7 3.1 0.077 12.2 0.7 1.7 2 0 0 2 2 2 0 CotH protein TLD PF07534.11 CDJ66489.1 - 1.4e-27 96.3 0.4 2.8e-27 95.4 0.3 1.5 1 0 0 1 1 1 1 TLD DUF3801 PF12687.2 CDJ66489.1 - 0.03 13.8 0.1 0.03 13.8 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3801) BAF1_ABF1 PF04684.8 CDJ66490.1 - 0.0024 16.8 34.3 0.0024 16.8 23.8 3.0 1 1 2 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor AAA_23 PF13476.1 CDJ66490.1 - 1.1 9.5 28.3 3.3 7.9 10.1 2.3 2 0 0 2 2 2 0 AAA domain Utp14 PF04615.8 CDJ66490.1 - 2.4 6.2 45.2 3.4 5.7 31.4 1.1 1 0 0 1 1 1 0 Utp14 protein TGS PF02824.16 CDJ66491.1 - 2.5e-14 52.8 0.0 3.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 TGS domain AARP2CN PF08142.7 CDJ66492.1 - 8.8e-21 73.2 8.0 8.5e-13 47.6 0.9 3.2 3 0 0 3 3 2 2 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CDJ66492.1 - 0.00018 20.9 9.3 0.00018 20.9 6.5 2.9 1 1 0 2 2 1 1 Elongation factor Tu GTP binding domain SAPS PF04499.10 CDJ66492.1 - 0.00029 19.6 19.9 0.0012 17.5 1.7 2.1 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDJ66492.1 - 0.00073 17.4 25.2 0.0045 14.7 4.1 2.1 2 0 0 2 2 2 2 Ycf1 CDC45 PF02724.9 CDJ66492.1 - 0.0017 16.4 3.9 0.0017 16.4 2.7 2.2 2 0 0 2 2 2 2 CDC45-like protein CAF-1_p150 PF11600.3 CDJ66492.1 - 0.002 17.5 31.0 0.002 17.5 21.5 3.1 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Anoctamin PF04547.7 CDJ66492.1 - 0.0021 16.8 6.2 0.0021 16.8 4.3 2.3 2 0 0 2 2 2 1 Calcium-activated chloride channel DUF605 PF04652.11 CDJ66492.1 - 0.0025 17.2 75.9 0.006 16.0 25.4 2.2 2 0 0 2 2 2 2 Vta1 like SAGA-Tad1 PF12767.2 CDJ66492.1 - 0.0032 17.1 53.1 0.012 15.2 10.7 2.6 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Pex14_N PF04695.8 CDJ66492.1 - 0.0066 16.5 19.4 0.0066 16.5 13.4 3.5 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Caldesmon PF02029.10 CDJ66492.1 - 0.014 13.8 29.0 0.0034 15.8 4.6 2.2 2 0 0 2 2 2 0 Caldesmon CPSF100_C PF13299.1 CDJ66492.1 - 0.081 13.1 33.1 0.24 11.5 7.6 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.7 CDJ66492.1 - 0.18 11.6 46.6 1.1 9.0 14.7 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.8 CDJ66492.1 - 0.27 10.6 38.1 1.1 8.7 9.7 2.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2201_N PF13203.1 CDJ66492.1 - 0.33 10.0 46.3 0.021 14.0 11.0 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain Zip PF02535.17 CDJ66492.1 - 0.37 9.7 15.5 0.15 11.0 1.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Raftlin PF15250.1 CDJ66492.1 - 0.41 9.1 40.4 0.6 8.5 12.5 2.1 2 0 0 2 2 2 0 Raftlin PAT1 PF09770.4 CDJ66492.1 - 0.69 8.0 125.7 0.063 11.5 37.9 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDJ66492.1 - 0.96 9.1 41.8 3.5 7.3 10.7 2.5 2 0 0 2 2 2 0 DDHD domain Tyrosinase PF00264.15 CDJ66492.1 - 1.3 9.1 24.9 3.1 7.8 7.4 2.3 2 0 0 2 2 2 0 Common central domain of tyrosinase Presenilin PF01080.12 CDJ66492.1 - 1.6 7.5 33.1 0.85 8.3 8.2 2.1 2 0 0 2 2 2 0 Presenilin G-alpha PF00503.15 CDJ66492.1 - 3 6.4 39.4 0.0052 15.5 5.1 2.4 2 0 0 2 2 2 0 G-protein alpha subunit FLO_LFY PF01698.11 CDJ66492.1 - 3.2 6.5 41.1 2.3 7.0 10.3 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein SprA-related PF12118.3 CDJ66492.1 - 3.5 6.8 116.4 0.043 13.1 30.2 2.4 2 1 0 2 2 2 0 SprA-related family Draxin PF15550.1 CDJ66492.1 - 5.2 6.6 32.0 3.6 7.1 8.4 2.5 2 0 0 2 2 2 0 Draxin GOLD_2 PF13897.1 CDJ66492.1 - 5.2 7.3 17.5 4.4 7.5 2.8 2.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking RAP1 PF07218.6 CDJ66492.1 - 5.9 4.8 4.7 6.2 4.7 1.9 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Pal1 PF08316.6 CDJ66492.1 - 6.2 7.2 24.1 1.1 9.7 4.1 2.5 2 0 0 2 2 2 0 Pal1 cell morphology protein DUF940 PF06082.6 CDJ66492.1 - 6.4 5.1 30.6 0.39 9.2 6.3 2.1 2 0 0 2 2 2 0 Bacterial putative lipoprotein (DUF940) LicD PF04991.8 CDJ66492.1 - 6.4 6.8 8.3 16 5.5 0.5 2.4 2 0 0 2 2 2 0 LicD family TT_ORF1 PF02956.9 CDJ66492.1 - 7.6 4.8 31.8 0.63 8.4 6.1 2.2 2 0 0 2 2 2 0 TT viral orf 1 AvrE PF11725.3 CDJ66492.1 - 7.9 3.3 42.6 2 5.3 10.1 2.0 2 0 0 2 2 2 0 Pathogenicity factor DUF2828 PF11443.3 CDJ66492.1 - 9.3 4.3 24.9 0.28 9.3 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Herpes_env PF01673.13 CDJ66492.1 - 9.3 4.6 24.2 0.97 7.9 3.7 2.2 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein PP2C PF00481.16 CDJ66493.1 - 1.5e-06 27.7 0.0 1.6e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PepSY PF03413.14 CDJ66493.1 - 7.4e-05 23.3 0.1 9.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain SpoIIE PF07228.7 CDJ66493.1 - 0.072 12.7 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) SR-25 PF10500.4 CDJ66494.1 - 0.00014 21.4 6.0 0.00014 21.4 4.1 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1053 PF06327.9 CDJ66494.1 - 0.063 13.6 2.7 5.4 7.4 0.2 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) Ctr PF04145.10 CDJ66494.1 - 0.23 11.5 4.2 2.2 8.3 0.5 2.4 2 0 0 2 2 2 0 Ctr copper transporter family RAB3GAP2_N PF14655.1 CDJ66494.1 - 0.85 8.5 16.6 0.19 10.6 0.2 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF702 PF05142.7 CDJ66494.1 - 8.6 6.5 13.7 0.6 10.2 3.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF702) Lactamase_B_2 PF12706.2 CDJ66496.1 - 3.8e-09 36.3 0.0 6.9e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDJ66496.1 - 3.4e-08 33.3 0.0 2.7e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily SR-25 PF10500.4 CDJ66498.1 - 0.00063 19.2 2.2 0.00063 19.2 1.5 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Metallophos PF00149.23 CDJ66499.1 - 2.1e-09 37.0 0.0 2.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDJ66499.1 - 0.0084 15.9 0.0 0.0097 15.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Activator-TraM PF11657.3 CDJ66499.1 - 0.054 12.9 0.1 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Transcriptional activator TraM DNA_pol_E_B PF04042.11 CDJ66499.1 - 0.063 12.5 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B TPP_enzyme_N PF02776.13 CDJ66499.1 - 0.13 11.6 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF4349 PF14257.1 CDJ66500.1 - 0.00086 18.6 10.2 0.00086 18.6 7.1 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4349) Cnd1_N PF12922.2 CDJ66500.1 - 6.2 6.4 7.0 7.7 6.1 0.1 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term PFK PF00365.15 CDJ66502.1 - 9.5e-28 96.9 0.1 2.3e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase Hydrolase_3 PF08282.7 CDJ66503.1 - 2e-43 148.8 0.0 2.4e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CDJ66503.1 - 1.7e-07 30.7 0.1 0.00033 20.0 0.1 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CDJ66503.1 - 0.0023 18.3 0.4 0.01 16.2 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Clathrin_bdg PF15045.1 CDJ66503.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking HAD PF12710.2 CDJ66503.1 - 0.039 14.0 1.2 0.29 11.2 0.8 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GCOM2 PF15328.1 CDJ66505.1 - 8.6 6.0 20.6 0.046 13.4 6.3 2.6 2 1 1 3 3 3 0 Putative GRINL1B complex locus protein 2 Acyl_transf_1 PF00698.16 CDJ66506.1 - 7.5e-10 38.6 7.7 1.2e-05 24.8 2.7 2.0 1 1 1 2 2 2 2 Acyl transferase domain TFIIA PF03153.8 CDJ66506.1 - 0.1 12.4 2.1 0.12 12.2 1.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CH PF00307.26 CDJ66506.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain Macoilin PF09726.4 CDJ66506.1 - 0.25 9.5 4.9 0.24 9.6 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4228 PF14009.1 CDJ66506.1 - 0.28 11.3 6.4 0.68 10.0 4.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Period_C PF12114.3 CDJ66506.1 - 1.7 8.1 15.1 2.4 7.7 10.5 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF2051 PF09738.4 CDJ66506.1 - 2.7 7.1 5.6 4 6.6 3.9 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Corona_nucleoca PF00937.13 CDJ66506.1 - 3.5 6.4 6.2 4.6 6.0 4.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CAF-1_p150 PF11600.3 CDJ66506.1 - 4.8 6.5 6.4 6.2 6.1 4.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Presenilin PF01080.12 CDJ66507.1 - 0.0011 17.8 4.3 0.0013 17.6 3.0 1.0 1 0 0 1 1 1 1 Presenilin Plasmodium_Vir PF05795.6 CDJ66507.1 - 0.0063 15.7 0.9 0.0076 15.4 0.6 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein SR-25 PF10500.4 CDJ66507.1 - 0.016 14.6 13.9 0.022 14.2 9.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DHHW PF14286.1 CDJ66507.1 - 0.054 12.8 7.6 0.055 12.7 5.3 1.0 1 0 0 1 1 1 0 DHHW protein Spore_coat_CotO PF14153.1 CDJ66507.1 - 0.087 12.2 9.2 0.12 11.8 6.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PAT1 PF09770.4 CDJ66507.1 - 0.13 10.5 18.6 0.14 10.3 12.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDJ66507.1 - 0.15 11.6 8.3 0.16 11.5 5.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CDK5_activator PF03261.10 CDJ66507.1 - 0.16 11.2 8.3 0.18 11.1 5.7 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Dsh_C PF12316.3 CDJ66507.1 - 0.23 11.5 12.9 0.27 11.3 8.9 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SRP-alpha_N PF04086.8 CDJ66507.1 - 0.32 10.3 10.0 0.36 10.1 7.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAM60A PF15396.1 CDJ66507.1 - 0.4 10.3 9.1 0.48 10.1 6.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A OmpH PF03938.9 CDJ66507.1 - 0.6 10.0 24.3 0.78 9.6 16.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HpaP PF09483.5 CDJ66507.1 - 0.61 10.0 17.7 0.77 9.6 12.3 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) TMEM51 PF15345.1 CDJ66507.1 - 0.63 9.7 8.7 0.79 9.3 6.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 MIP-T3 PF10243.4 CDJ66507.1 - 0.82 8.0 18.4 0.94 7.8 12.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Suf PF05843.9 CDJ66507.1 - 0.87 9.2 11.0 1.3 8.7 7.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 CDJ66507.1 - 0.95 7.1 4.5 0.99 7.0 3.2 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 CDJ66507.1 - 1 9.2 7.9 1.2 8.9 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.8 CDJ66507.1 - 1.1 9.0 21.4 1.4 8.6 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAP1 PF07218.6 CDJ66507.1 - 1.4 6.9 10.5 1.5 6.7 7.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Band_3_cyto PF07565.8 CDJ66507.1 - 1.6 8.1 7.6 2 7.8 5.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ndc1_Nup PF09531.5 CDJ66507.1 - 1.6 7.0 8.7 1.7 6.9 6.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF812 PF05667.6 CDJ66507.1 - 1.8 6.9 15.7 2.2 6.6 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TCP PF03634.8 CDJ66507.1 - 1.9 8.8 18.8 3.2 8.1 13.1 1.4 1 0 0 1 1 1 0 TCP family transcription factor SARG PF15385.1 CDJ66507.1 - 2 7.6 17.7 2.5 7.3 12.2 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Med5 PF08689.5 CDJ66507.1 - 2.1 5.9 9.7 2.4 5.7 6.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 DUF1510 PF07423.6 CDJ66507.1 - 2.5 7.4 13.4 3.1 7.1 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 CDJ66507.1 - 2.6 6.6 8.3 2.8 6.4 5.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4551 PF15087.1 CDJ66507.1 - 2.7 6.2 8.3 3 6.0 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pex16 PF08610.5 CDJ66507.1 - 3 6.7 6.6 3.4 6.5 4.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF1675 PF07897.6 CDJ66507.1 - 3 7.6 14.1 3.7 7.3 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF966 PF06136.8 CDJ66507.1 - 3.1 7.1 15.2 3.6 6.9 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PPP4R2 PF09184.6 CDJ66507.1 - 3.4 7.1 7.8 4 6.9 5.4 1.1 1 0 0 1 1 1 0 PPP4R2 Neur_chan_memb PF02932.11 CDJ66507.1 - 3.5 7.4 7.3 3.8 7.3 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GET2 PF08690.5 CDJ66507.1 - 3.6 6.7 8.9 3.8 6.6 6.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4175 PF13779.1 CDJ66507.1 - 4.3 4.9 24.4 5.1 4.6 16.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Parvo_coat PF00740.13 CDJ66507.1 - 4.5 6.1 12.1 5.3 5.8 8.4 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF4569 PF15133.1 CDJ66507.1 - 4.5 6.5 15.3 5.3 6.3 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Med15 PF09606.5 CDJ66507.1 - 4.6 5.3 26.5 5.1 5.1 18.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2371 PF10177.4 CDJ66507.1 - 4.8 7.0 7.9 1.5 8.7 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) Lin-8 PF03353.10 CDJ66507.1 - 4.8 6.3 12.1 5.4 6.1 8.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.4 CDJ66507.1 - 5.1 5.2 16.0 5.9 5.0 11.1 1.0 1 0 0 1 1 1 0 Transmembrane protein CDC27 PF09507.5 CDJ66507.1 - 6.5 5.8 19.1 7.8 5.5 13.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4407 PF14362.1 CDJ66507.1 - 6.7 5.5 20.0 8.5 5.2 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2076 PF09849.4 CDJ66507.1 - 7 6.6 30.2 46 3.9 20.9 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Paramyxo_C PF01692.13 CDJ66507.1 - 7.5 6.1 12.0 11 5.5 8.3 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c DUF2413 PF10310.4 CDJ66507.1 - 7.8 5.1 21.8 9.4 4.9 15.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2201_N PF13203.1 CDJ66507.1 - 8.9 5.3 17.1 11 5.0 11.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.2 CDJ66507.1 - 9.1 3.8 12.3 10 3.6 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3533 PF12051.3 CDJ66507.1 - 9.2 4.8 11.5 11 4.6 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF572 PF04502.8 CDJ66507.1 - 9.2 5.3 13.7 12 5.0 9.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AUX_IAA PF02309.11 CDJ66507.1 - 9.6 5.8 10.1 14 5.3 7.0 1.3 1 0 0 1 1 1 0 AUX/IAA family rve PF00665.21 CDJ66508.1 - 7.2e-14 51.9 0.1 3.8e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 CDJ66508.1 - 0.003 16.9 1.1 0.0058 16.0 0.7 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 CDJ66508.1 - 0.028 13.9 0.3 0.18 11.3 0.1 2.3 2 0 0 2 2 2 0 Integrase core domain GLTSCR1 PF15249.1 CDJ66508.1 - 0.09 12.8 0.2 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region THRAP3_BCLAF1 PF15440.1 CDJ66509.1 - 0.0074 14.9 9.3 0.0084 14.8 6.4 1.1 1 0 0 1 1 1 1 THRAP3/BCLAF1 family Mitofilin PF09731.4 CDJ66509.1 - 0.42 9.2 26.3 0.51 8.9 18.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SR-25 PF10500.4 CDJ66509.1 - 3.9 6.8 32.6 0.1 12.0 17.3 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S46 PF10459.4 CDJ66509.1 - 6.6 5.0 20.0 8.7 4.6 13.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Med15 PF09606.5 CDJ66511.1 - 0.00088 17.6 23.7 0.0012 17.1 16.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ66511.1 - 0.0034 15.6 14.6 0.0036 15.6 10.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF966 PF06136.8 CDJ66511.1 - 0.034 13.5 12.1 0.047 13.1 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FAM176 PF14851.1 CDJ66511.1 - 0.34 10.5 2.7 1.3 8.7 0.7 2.0 2 0 0 2 2 2 0 FAM176 family SeqA PF03925.8 CDJ66511.1 - 0.56 9.8 7.2 0.18 11.5 3.1 1.5 2 0 0 2 2 2 0 SeqA protein Suf PF05843.9 CDJ66511.1 - 0.56 9.8 8.1 2.2 7.9 4.7 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AUX_IAA PF02309.11 CDJ66511.1 - 0.89 9.2 5.9 7.8 6.1 2.9 2.1 2 0 0 2 2 2 0 AUX/IAA family Ribosomal_60s PF00428.14 CDJ66511.1 - 1.2 9.5 15.6 3.4 8.1 10.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pex14_N PF04695.8 CDJ66511.1 - 2 8.4 23.5 0.85 9.6 6.5 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phage_Gp23 PF10669.4 CDJ66511.1 - 4.5 7.3 5.8 7.7 6.6 4.0 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF3347 PF11827.3 CDJ66511.1 - 5.8 6.8 12.3 4.1 7.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF4557 PF15101.1 CDJ66511.1 - 6.1 6.6 13.8 1.8 8.3 7.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) CDK5_activator PF03261.10 CDJ66511.1 - 9.3 5.4 14.4 0.4 9.9 5.1 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein YfhO PF09586.5 CDJ66513.1 - 0.0021 16.1 4.3 0.0028 15.7 3.0 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Peptidase_S49_N PF08496.5 CDJ66513.1 - 0.0037 17.0 0.4 0.0059 16.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Med15 PF09606.5 CDJ66513.1 - 0.012 13.8 10.9 0.015 13.5 7.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ66513.1 - 0.013 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.8 CDJ66513.1 - 0.019 15.0 2.0 0.031 14.3 1.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pex24p PF06398.6 CDJ66513.1 - 0.044 12.5 0.1 0.062 12.0 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF778 PF05608.7 CDJ66513.1 - 0.06 13.2 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF4446 PF14584.1 CDJ66513.1 - 0.062 13.1 0.7 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2572 PF10833.3 CDJ66513.1 - 0.086 12.2 6.7 0.14 11.5 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF4557 PF15101.1 CDJ66513.1 - 0.087 12.6 6.9 0.12 12.1 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Neur_chan_memb PF02932.11 CDJ66513.1 - 0.096 12.5 0.1 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.10 CDJ66513.1 - 0.25 11.3 3.0 0.29 11.1 1.3 1.6 1 1 0 1 1 1 0 Ctr copper transporter family ETRAMP PF09716.5 CDJ66513.1 - 1.9 8.4 6.6 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) E_Pc_C PF06752.7 CDJ66513.1 - 6.3 6.2 16.5 11 5.4 11.4 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Na_Pi_cotrans PF02690.10 CDJ66514.1 - 0.033 13.9 0.2 0.04 13.6 0.1 1.1 1 0 0 1 1 1 0 Na+/Pi-cotransporter DUF1925 PF09094.6 CDJ66514.1 - 0.25 11.3 0.9 0.87 9.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1925) IncA PF04156.9 CDJ66514.1 - 0.67 9.5 21.0 1 8.9 14.6 1.4 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 CDJ66514.1 - 1.3 9.4 5.9 1.8 8.9 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HGTP_anticodon2 PF12745.2 CDJ66517.1 - 0.44 9.6 5.7 0.49 9.4 0.7 2.3 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Neur_chan_memb PF02932.11 CDJ66517.1 - 0.76 9.6 3.2 2.1 8.1 2.2 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 CDJ66518.1 - 2.4e-05 23.9 5.6 2.4e-05 23.9 3.9 5.1 5 1 0 5 5 5 3 Nuclear RNA-splicing-associated protein zf-RING_2 PF13639.1 CDJ66518.1 - 0.51 10.2 9.7 0.051 13.4 1.3 2.5 2 0 0 2 2 2 0 Ring finger domain Spt20 PF12090.3 CDJ66518.1 - 2.6 7.3 17.9 1.4 8.1 0.2 3.3 3 0 0 3 3 3 0 Spt20 family SR-25 PF10500.4 CDJ66519.1 - 6.6e-06 25.7 5.3 6.6e-06 25.7 3.7 2.7 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2217 PF10265.4 CDJ66519.1 - 0.0068 15.2 8.7 0.0068 15.2 6.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2217) zf-RING_2 PF13639.1 CDJ66519.1 - 0.017 14.9 2.0 0.017 14.9 1.4 2.4 2 0 0 2 2 2 0 Ring finger domain Cwf_Cwc_15 PF04889.7 CDJ66519.1 - 0.052 13.2 3.1 0.77 9.4 0.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Transposase_24 PF03004.9 CDJ66519.1 - 2.5 7.9 9.9 0.34 10.8 0.6 2.3 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) OmpH PF03938.9 CDJ66520.1 - 0.31 10.9 0.0 0.31 10.9 0.0 9.4 4 4 2 6 6 6 0 Outer membrane protein (OmpH-like) DUF4614 PF15391.1 CDJ66522.1 - 0.14 11.9 16.9 0.15 11.7 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) bZIP_C PF12498.3 CDJ66522.1 - 1.7 9.8 13.3 2.2 9.5 9.2 1.1 1 0 0 1 1 1 0 Basic leucine-zipper C terminal FAM60A PF15396.1 CDJ66523.1 - 0.0013 18.5 25.1 0.0021 17.8 17.4 1.3 1 0 0 1 1 1 1 Protein Family FAM60A Exonuc_VII_L PF02601.10 CDJ66523.1 - 0.011 15.0 26.8 0.014 14.6 18.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.11 CDJ66523.1 - 0.06 11.9 14.6 0.077 11.5 10.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Med15 PF09606.5 CDJ66523.1 - 0.11 10.7 103.2 0.19 9.8 71.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AvrE PF11725.3 CDJ66523.1 - 0.16 8.9 30.9 0.19 8.7 21.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor CDC45 PF02724.9 CDJ66523.1 - 0.25 9.3 35.8 0.35 8.8 24.8 1.2 1 0 0 1 1 1 0 CDC45-like protein YjgP_YjgQ PF03739.9 CDJ66523.1 - 0.37 9.4 5.9 0.89 8.2 4.1 1.5 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4045 PF13254.1 CDJ66523.1 - 2.3 7.4 30.8 4 6.6 21.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.2 CDJ66523.1 - 2.9 5.4 40.8 4.1 4.9 28.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDJ66523.1 - 4.8 5.4 26.4 6.7 5.0 18.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 CDJ66524.1 - 0.045 12.0 56.6 0.053 11.7 39.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ACPS PF01648.15 CDJ66524.1 - 0.15 11.8 3.5 5 6.9 0.2 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily AAA_28 PF13521.1 CDJ66524.1 - 0.41 10.6 8.1 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain TOM13 PF08219.6 CDJ66524.1 - 0.67 9.7 2.8 16 5.3 0.1 2.4 2 0 0 2 2 2 0 Outer membrane protein TOM13 DUF4045 PF13254.1 CDJ66524.1 - 1.6 7.8 14.8 2.1 7.5 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF912 PF06024.7 CDJ66524.1 - 7.2 6.7 9.0 15 5.7 0.9 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Zip PF02535.17 CDJ66524.1 - 7.2 5.5 19.8 12 4.7 13.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1180 PF06679.7 CDJ66524.1 - 7.7 6.3 6.1 85 2.9 4.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) A_deamin PF02137.13 CDJ66524.1 - 8.7 5.5 23.5 10 5.3 5.9 2.1 1 1 1 2 2 2 0 Adenosine-deaminase (editase) domain DUF383 PF04063.9 CDJ66525.1 - 0.65 9.5 2.3 2.4 7.6 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF383) SicP-binding PF09119.5 CDJ66525.1 - 1.7 8.3 4.5 0.91 9.2 0.1 2.7 2 2 1 3 3 3 0 SicP binding DUF2217 PF10265.4 CDJ66525.1 - 2.8 6.5 11.1 3.8 6.1 7.7 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) gag-asp_proteas PF13975.1 CDJ66527.1 - 0.00029 20.5 0.0 0.00069 19.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ66527.1 - 0.002 18.5 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF3552 PF12072.3 CDJ66527.1 - 0.0042 16.3 1.3 0.0065 15.7 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) FCP1_C PF09309.5 CDJ66528.1 - 0.71 9.1 14.9 0.4 9.9 5.3 2.0 1 1 1 2 2 2 0 FCP1, C-terminal FLO_LFY PF01698.11 CDJ66528.1 - 0.74 8.6 10.9 0.86 8.3 7.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Med15 PF09606.5 CDJ66528.1 - 3.4 5.7 31.1 3.7 5.6 21.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ66528.1 - 4 7.2 17.7 5.1 6.9 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CcmD PF04995.9 CDJ66529.1 - 0.021 14.5 0.2 0.036 13.7 0.2 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SR-25 PF10500.4 CDJ66529.1 - 1.5 8.2 16.1 0.64 9.4 7.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MSP1_C PF07462.6 CDJ66529.1 - 1.8 6.8 6.6 2.5 6.3 4.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus APC_CDC26 PF10471.4 CDJ66529.1 - 4.4 8.1 11.7 1 10.1 4.6 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF755 PF05501.6 CDJ66529.1 - 9 6.3 18.2 8.1 6.5 7.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PsbI PF02532.9 CDJ66530.1 - 0.086 12.4 2.9 0.17 11.5 2.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Ribosomal_60s PF00428.14 CDJ66531.1 - 0.08 13.3 15.4 0.087 13.2 9.6 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein X PF00739.14 CDJ66531.1 - 0.13 12.1 2.6 0.18 11.6 1.8 1.3 1 1 0 1 1 1 0 Trans-activation protein X Shadoo PF14999.1 CDJ66531.1 - 3.4 7.5 13.3 0.49 10.2 6.7 1.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF1510 PF07423.6 CDJ66532.1 - 0.0021 17.4 6.7 0.0022 17.3 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4446 PF14584.1 CDJ66532.1 - 0.019 14.8 1.6 0.025 14.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF913 PF06025.7 CDJ66532.1 - 0.11 11.2 4.7 0.13 11.0 3.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.1 CDJ66532.1 - 0.13 11.9 7.4 0.15 11.8 5.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ycf1 PF05758.7 CDJ66532.1 - 0.15 9.7 8.5 0.15 9.7 5.9 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 CDJ66532.1 - 0.15 11.8 10.2 0.17 11.6 7.1 1.1 1 0 0 1 1 1 0 DDHD domain AUX_IAA PF02309.11 CDJ66532.1 - 0.16 11.6 11.3 0.19 11.4 7.8 1.0 1 0 0 1 1 1 0 AUX/IAA family RIC3 PF15361.1 CDJ66532.1 - 0.19 11.9 13.8 0.23 11.6 9.6 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Suf PF05843.9 CDJ66532.1 - 0.38 10.4 19.2 0.52 9.9 13.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDK5_activator PF03261.10 CDJ66532.1 - 0.43 9.8 8.5 0.48 9.7 5.9 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4220 PF13968.1 CDJ66532.1 - 0.54 9.2 2.9 0.58 9.2 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SprA-related PF12118.3 CDJ66532.1 - 0.56 9.4 38.8 0.69 9.1 26.9 1.1 1 0 0 1 1 1 0 SprA-related family FLO_LFY PF01698.11 CDJ66532.1 - 0.57 8.9 12.6 0.66 8.7 8.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein FNIP_N PF14636.1 CDJ66532.1 - 0.64 10.4 12.5 0.79 10.1 8.7 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Spore_coat_CotO PF14153.1 CDJ66532.1 - 0.74 9.2 20.2 0.92 8.9 14.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Pox_Ag35 PF03286.9 CDJ66532.1 - 0.84 9.1 8.7 1 8.8 6.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hom_end_hint PF05203.11 CDJ66532.1 - 0.84 9.3 6.6 1 9.0 4.6 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Zip PF02535.17 CDJ66532.1 - 0.86 8.5 3.7 0.95 8.4 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SAGA-Tad1 PF12767.2 CDJ66532.1 - 0.96 9.0 18.6 1.1 8.8 12.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit IncA PF04156.9 CDJ66532.1 - 1.2 8.6 21.2 1.6 8.3 14.7 1.2 1 0 0 1 1 1 0 IncA protein DUF2126 PF09899.4 CDJ66532.1 - 1.3 6.9 8.3 1.5 6.7 5.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4544 PF15077.1 CDJ66532.1 - 1.4 8.3 4.1 1.6 8.1 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Neur_chan_memb PF02932.11 CDJ66532.1 - 1.5 8.6 10.4 1.7 8.4 7.2 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 CDJ66532.1 - 1.6 7.1 4.0 1.8 6.9 2.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier Raftlin PF15250.1 CDJ66532.1 - 1.6 7.1 13.4 1.9 6.8 9.3 1.0 1 0 0 1 1 1 0 Raftlin Sec62 PF03839.11 CDJ66532.1 - 1.7 8.0 7.7 1.9 7.8 5.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 PIH1 PF08190.7 CDJ66532.1 - 1.7 8.0 18.4 2 7.7 12.8 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Presenilin PF01080.12 CDJ66532.1 - 1.8 7.2 6.6 2 7.1 4.6 1.1 1 0 0 1 1 1 0 Presenilin DUF853 PF05872.7 CDJ66532.1 - 1.8 6.7 10.6 2.3 6.4 7.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Herpes_DNAp_acc PF04929.7 CDJ66532.1 - 2.9 6.7 10.8 3.3 6.5 7.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4638 PF15472.1 CDJ66532.1 - 3 7.3 12.4 3.4 7.1 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Band_3_cyto PF07565.8 CDJ66532.1 - 3.5 7.0 14.3 4.5 6.6 9.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDJ66532.1 - 3.8 5.6 40.9 4.5 5.4 28.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MDFI PF15316.1 CDJ66532.1 - 5.7 6.9 9.5 7.2 6.5 6.6 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF3260 PF11658.3 CDJ66532.1 - 5.9 4.9 10.5 6.8 4.7 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) MRP-S26 PF14943.1 CDJ66532.1 - 6.6 6.2 18.0 8.7 5.8 12.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 TFIIA PF03153.8 CDJ66532.1 - 6.8 6.4 30.0 8.1 6.2 20.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CKAP2_C PF15297.1 CDJ66532.1 - 8.3 5.1 16.7 10 4.7 11.5 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Hid1 PF12722.2 CDJ66532.1 - 8.3 3.9 15.0 9.8 3.7 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SseC PF04888.7 CDJ66533.1 - 0.00011 21.6 9.5 0.00011 21.6 6.6 4.4 4 1 0 4 4 4 1 Secretion system effector C (SseC) like family PAT1 PF09770.4 CDJ66534.1 - 2.4e-05 22.8 28.7 2.4e-05 22.8 19.9 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ66534.1 - 0.00024 19.4 42.9 0.00027 19.2 29.7 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_coat_CotO PF14153.1 CDJ66534.1 - 0.0026 17.2 23.7 0.0036 16.7 16.4 1.3 1 0 0 1 1 1 1 Spore coat protein CotO CDC45 PF02724.9 CDJ66534.1 - 0.0041 15.2 14.5 0.005 14.9 10.1 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIA PF03153.8 CDJ66534.1 - 0.0049 16.8 29.4 0.006 16.5 20.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.1 CDJ66534.1 - 0.017 13.7 13.2 0.021 13.3 9.1 1.1 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.7 CDJ66534.1 - 0.017 15.1 10.7 0.019 14.9 7.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SAGA-Tad1 PF12767.2 CDJ66534.1 - 0.029 14.0 17.2 0.039 13.6 11.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PIH1 PF08190.7 CDJ66534.1 - 0.073 12.4 21.3 0.11 11.9 14.7 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RR_TM4-6 PF06459.7 CDJ66534.1 - 0.093 12.6 16.7 0.15 11.9 11.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDJ66534.1 - 0.097 12.4 12.6 0.15 11.8 8.7 1.4 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 CDJ66534.1 - 0.19 10.7 1.9 0.24 10.3 1.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PLRV_ORF5 PF01690.12 CDJ66534.1 - 0.22 10.6 16.8 0.26 10.3 11.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Lin-8 PF03353.10 CDJ66534.1 - 0.28 10.4 18.7 0.37 10.0 12.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ycf1 PF05758.7 CDJ66534.1 - 0.31 8.6 19.1 0.37 8.4 13.3 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CDJ66534.1 - 0.37 10.6 10.9 0.47 10.3 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.6 CDJ66534.1 - 0.38 9.0 11.1 0.39 8.9 7.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.2 CDJ66534.1 - 0.5 7.9 18.0 0.54 7.8 12.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CMV_1a PF12467.3 CDJ66534.1 - 0.76 10.1 20.1 1.2 9.4 13.9 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family FAM60A PF15396.1 CDJ66534.1 - 0.84 9.3 15.8 1.2 8.8 10.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Herpes_DNAp_acc PF04929.7 CDJ66534.1 - 1 8.2 17.2 1.3 7.9 11.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor hDGE_amylase PF14701.1 CDJ66534.1 - 1.2 7.9 8.5 1.6 7.5 5.9 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Asp-B-Hydro_N PF05279.6 CDJ66534.1 - 1.5 8.5 19.9 2.3 7.9 13.8 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Rtf2 PF04641.7 CDJ66534.1 - 1.9 7.6 24.4 3.1 6.9 16.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger eIF-3_zeta PF05091.7 CDJ66534.1 - 1.9 6.9 21.5 2.5 6.6 14.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1675 PF07897.6 CDJ66534.1 - 2.2 8.0 16.0 3.2 7.5 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SPX PF03105.14 CDJ66534.1 - 2.3 7.9 17.9 3.4 7.3 12.4 1.2 1 0 0 1 1 1 0 SPX domain DUF1510 PF07423.6 CDJ66534.1 - 3.3 7.0 26.8 5.4 6.3 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ndc1_Nup PF09531.5 CDJ66534.1 - 4.1 5.7 13.5 4.8 5.4 9.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BORG_CEP PF14957.1 CDJ66534.1 - 4.1 8.3 12.4 8.9 7.2 8.6 1.6 1 0 0 1 1 1 0 Cdc42 effector Mem_trans PF03547.13 CDJ66534.1 - 4.7 5.3 5.1 5.9 5.0 3.5 1.2 1 0 0 1 1 1 0 Membrane transport protein Rhabdo_ncap PF00945.13 CDJ66534.1 - 7.1 5.1 11.0 10 4.6 7.6 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF4544 PF15077.1 CDJ66534.1 - 7.2 6.0 11.3 13 5.1 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Presenilin PF01080.12 CDJ66534.1 - 8.9 5.0 15.3 12 4.6 10.6 1.1 1 0 0 1 1 1 0 Presenilin Pex16 PF08610.5 CDJ66534.1 - 9.1 5.1 14.3 16 4.3 9.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Prenyltrans PF00432.16 CDJ66535.1 - 4.5e-40 134.8 28.3 8.3e-10 38.0 0.0 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CDJ66535.1 - 1.5e-27 96.2 1.6 6.1e-12 45.9 0.1 3.9 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CDJ66535.1 - 1.5e-12 47.4 0.0 2.2e-06 27.6 0.0 3.2 2 1 0 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 CDJ66535.1 - 0.00039 19.7 0.0 0.019 14.2 0.0 2.3 2 0 0 2 2 2 1 A-macroglobulin complement component CAP_N PF01213.14 CDJ66535.1 - 1.7 7.8 3.9 2.6 7.2 2.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.11 CDJ66536.1 - 3.7e-28 98.2 30.2 3.2e-23 82.0 9.9 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CDJ66536.1 - 0.0012 18.5 0.0 0.0085 15.8 0.0 2.4 2 0 0 2 2 2 1 MFS_1 like family ATG22 PF11700.3 CDJ66536.1 - 0.0017 16.9 1.2 0.0017 16.9 0.8 2.5 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like CDC50 PF03381.10 CDJ66538.1 - 8.3e-60 202.3 0.0 1.1e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mlo PF03094.10 CDJ66540.1 - 0.00018 19.7 11.4 0.0022 16.2 7.9 2.0 1 1 0 1 1 1 1 Mlo family FtsX PF02687.16 CDJ66540.1 - 1 9.1 8.6 0.26 11.0 2.2 2.0 2 0 0 2 2 2 0 FtsX-like permease family DFP PF04127.10 CDJ66541.1 - 8.5e-13 48.3 11.6 3.4e-09 36.5 0.0 4.3 3 1 1 4 4 4 3 DNA / pantothenate metabolism flavoprotein TPR_11 PF13414.1 CDJ66542.1 - 8.4e-16 57.3 16.8 1.9e-12 46.6 1.5 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CDJ66542.1 - 2.4e-13 49.0 9.5 1.7e-06 27.3 0.6 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ66542.1 - 7.2e-12 44.2 12.5 0.00016 21.3 0.2 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ66542.1 - 7.8e-06 25.7 1.4 7.8e-06 25.7 1.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ66542.1 - 0.00026 21.5 1.3 0.00026 21.5 0.9 3.3 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ66542.1 - 0.00043 20.2 4.3 0.00089 19.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat UPF0560 PF10577.4 CDJ66542.1 - 0.0016 16.7 12.3 0.0016 16.7 8.5 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0560 SPX PF03105.14 CDJ66542.1 - 0.16 11.7 37.8 0.08 12.7 9.9 2.3 2 0 0 2 2 2 0 SPX domain TPR_8 PF13181.1 CDJ66542.1 - 0.19 11.6 12.7 2.2 8.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PAT1 PF09770.4 CDJ66542.1 - 0.28 9.3 63.5 0.22 9.7 18.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDJ66542.1 - 0.49 8.0 73.1 0.03 12.0 26.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Lin-8 PF03353.10 CDJ66542.1 - 0.71 9.0 43.6 0.51 9.5 10.7 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SOBP PF15279.1 CDJ66542.1 - 0.93 9.8 32.9 3.4 7.9 9.4 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein CKAP2_C PF15297.1 CDJ66542.1 - 3.7 6.2 42.4 0.3 9.8 12.5 2.4 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus PTPA PF03095.10 CDJ66543.1 - 7.8e-90 301.0 0.0 1.1e-89 300.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Sugar_tr PF00083.19 CDJ66544.1 - 0.75 8.3 2.0 2.5 6.5 1.4 1.9 1 0 0 1 1 1 0 Sugar (and other) transporter MIP PF00230.15 CDJ66545.1 - 9.4e-15 54.6 32.1 7.3e-08 32.1 9.9 3.8 1 1 2 3 3 3 3 Major intrinsic protein AAA PF00004.24 CDJ66546.1 - 1.6e-43 148.0 0.0 2.7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDJ66546.1 - 3e-07 30.6 0.3 0.00053 20.1 0.0 2.6 2 1 1 3 3 2 2 AAA domain AAA_2 PF07724.9 CDJ66546.1 - 7.2e-07 29.2 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CDJ66546.1 - 6.7e-06 25.3 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CDJ66546.1 - 1.3e-05 24.9 0.2 8.4e-05 22.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDJ66546.1 - 1.3e-05 25.2 0.0 7.1e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CDJ66546.1 - 1.7e-05 23.8 0.0 3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CDJ66546.1 - 0.00013 22.8 0.2 0.00039 21.2 0.1 1.8 1 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CDJ66546.1 - 0.00019 20.8 0.3 0.02 14.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CDJ66546.1 - 0.00025 20.9 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CDJ66546.1 - 0.00038 19.9 0.0 0.00078 18.9 0.0 1.5 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CDJ66546.1 - 0.0006 20.1 0.1 0.0014 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDJ66546.1 - 0.00073 19.2 0.5 0.0015 18.2 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CDJ66546.1 - 0.00095 19.0 0.0 0.0035 17.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 CDJ66546.1 - 0.0016 18.4 0.1 0.0035 17.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 CDJ66546.1 - 0.0021 16.8 0.0 0.0043 15.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 CDJ66546.1 - 0.003 16.6 0.1 0.0065 15.5 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 CDJ66546.1 - 0.004 16.3 0.0 0.0076 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CDJ66546.1 - 0.0052 16.9 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 CDJ66546.1 - 0.0052 16.3 0.1 0.015 14.9 0.1 1.7 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 CDJ66546.1 - 0.0056 16.3 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_3 PF07726.6 CDJ66546.1 - 0.009 15.6 0.1 0.036 13.6 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CDJ66546.1 - 0.011 15.5 0.1 0.084 12.5 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 CDJ66546.1 - 0.016 14.4 0.2 0.049 12.8 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.10 CDJ66546.1 - 0.02 14.5 0.6 0.26 10.9 0.1 2.7 2 1 0 2 2 2 0 NTPase NB-ARC PF00931.17 CDJ66546.1 - 0.02 13.7 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 CDJ66546.1 - 0.031 13.4 0.1 0.37 9.8 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_30 PF13604.1 CDJ66546.1 - 0.049 13.2 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CDJ66546.1 - 0.061 13.3 0.0 0.2 11.7 0.0 2.0 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 CDJ66546.1 - 0.062 12.8 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 CDJ66546.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 CDJ66546.1 - 0.083 12.3 0.1 0.44 9.9 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 CDJ66546.1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.9 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 CDJ66546.1 - 0.13 11.1 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PAT1 PF09770.4 CDJ66547.1 - 0.058 11.6 32.0 0.059 11.6 22.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDJ66547.1 - 0.18 11.4 9.4 0.21 11.2 6.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM60A PF15396.1 CDJ66547.1 - 0.34 10.6 4.9 0.43 10.2 3.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Spore_coat_CotO PF14153.1 CDJ66547.1 - 0.5 9.7 10.2 0.65 9.4 7.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF605 PF04652.11 CDJ66547.1 - 0.63 9.3 22.0 0.78 9.0 15.3 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 CDJ66547.1 - 1.1 8.9 17.7 1.7 8.2 12.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 CDJ66547.1 - 1.1 7.5 10.5 1.2 7.4 7.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Opi1 PF08618.5 CDJ66547.1 - 1.3 7.8 16.6 1.5 7.6 11.5 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 CDK2AP PF09806.4 CDJ66547.1 - 1.5 9.0 19.4 1.7 8.8 13.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DHHW PF14286.1 CDJ66547.1 - 1.5 8.0 6.7 1.9 7.7 4.7 1.2 1 0 0 1 1 1 0 DHHW protein DUF4551 PF15087.1 CDJ66547.1 - 2 6.6 10.4 2.5 6.3 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3192 PF11399.3 CDJ66547.1 - 2.8 7.8 6.0 5.8 6.8 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) Macoilin PF09726.4 CDJ66547.1 - 3 6.0 10.2 3.5 5.7 7.1 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CDJ66547.1 - 3.8 7.3 27.9 5.1 6.8 19.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GKAP PF03359.8 CDJ66547.1 - 3.9 6.9 18.1 5.2 6.5 12.5 1.1 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Lipoprotein_2 PF00921.12 CDJ66547.1 - 4.1 7.4 10.6 5.2 7.0 7.4 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein Apt1 PF10351.4 CDJ66547.1 - 4.6 5.9 7.6 5.7 5.6 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Band_3_cyto PF07565.8 CDJ66547.1 - 4.7 6.6 11.7 6 6.3 8.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4613 PF15390.1 CDJ66547.1 - 6.7 4.7 9.8 8.8 4.3 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CDK5_activator PF03261.10 CDJ66547.1 - 7.3 5.8 11.2 9.1 5.5 7.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Serinc PF03348.10 CDJ66547.1 - 8.4 4.9 6.4 12 4.4 4.4 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.11 CDJ66547.1 - 8.4 6.1 9.0 11 5.8 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ABC_tran PF00005.22 CDJ66548.1 - 2.4e-16 60.2 0.0 9.7e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDJ66548.1 - 5.1e-08 33.2 0.2 0.0047 16.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 CDJ66548.1 - 1.8e-07 30.6 0.4 0.00096 18.4 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CDJ66548.1 - 0.00011 21.3 0.0 0.34 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CDJ66548.1 - 0.00023 21.3 0.0 0.00048 20.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDJ66548.1 - 0.0013 18.1 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CDJ66548.1 - 0.004 16.3 0.0 0.0087 15.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CDJ66548.1 - 0.0043 17.3 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDJ66548.1 - 0.0059 16.4 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CDJ66548.1 - 0.0064 16.9 0.0 0.014 15.9 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein NACHT PF05729.7 CDJ66548.1 - 0.011 15.3 0.1 0.039 13.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 CDJ66548.1 - 0.012 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain UPF0079 PF02367.12 CDJ66548.1 - 0.036 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 CDJ66548.1 - 0.04 13.6 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CDJ66548.1 - 0.05 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 CDJ66548.1 - 0.058 13.3 0.0 0.098 12.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.1 CDJ66548.1 - 0.072 11.5 0.0 0.18 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 CDJ66548.1 - 0.079 11.6 0.0 0.37 9.4 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.16 CDJ66548.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UBA PF00627.26 CDJ66553.1 - 2e-08 33.8 0.6 4.7e-08 32.6 0.4 1.7 1 0 0 1 1 1 1 UBA/TS-N domain PUB PF09409.5 CDJ66553.1 - 2.6e-07 30.2 0.0 1.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 PUB domain CUE PF02845.11 CDJ66553.1 - 0.015 14.7 1.4 0.059 12.8 0.1 2.4 2 0 0 2 2 2 0 CUE domain DUF2344 PF10105.4 CDJ66553.1 - 0.02 14.3 0.8 0.05 13.0 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) PRP1_N PF06424.7 CDJ66554.1 - 0.0014 18.9 0.4 0.0026 18.1 0.3 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal AAA_23 PF13476.1 CDJ66554.1 - 0.031 14.6 4.4 0.03 14.6 3.1 1.1 1 0 0 1 1 1 0 AAA domain HemX PF04375.9 CDJ66554.1 - 0.048 12.2 21.6 0.062 11.8 14.9 1.0 1 0 0 1 1 1 0 HemX YL1 PF05764.8 CDJ66554.1 - 0.054 13.0 6.4 0.064 12.8 4.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PP2C_2 PF13672.1 CDJ66554.1 - 0.45 9.8 10.0 0.56 9.5 6.9 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C Suf PF05843.9 CDJ66554.1 - 5.6 6.6 8.7 6.3 6.4 6.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SET PF00856.23 CDJ66555.1 - 1.9e-19 70.5 3.1 2.2e-19 70.3 0.0 2.5 3 1 0 3 3 3 1 SET domain CDK2AP PF09806.4 CDJ66555.1 - 0.018 15.2 0.2 0.018 15.2 0.2 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PepSY_2 PF13670.1 CDJ66555.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SR-25 PF10500.4 CDJ66555.1 - 1.6 8.1 10.3 0.12 11.8 3.0 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BAMBI PF06211.7 CDJ66555.1 - 1.6 8.7 8.0 0.36 10.8 2.1 2.3 2 0 0 2 2 2 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Hep_59 PF07052.6 CDJ66555.1 - 5.6 7.3 7.1 2.1 8.7 0.5 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.14 CDJ66556.1 - 2.5e-76 256.6 0.0 3.3e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 Actin CcmH PF03918.9 CDJ66556.1 - 0.064 12.2 1.4 0.095 11.6 1.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein BAF1_ABF1 PF04684.8 CDJ66556.1 - 0.12 11.1 5.9 0.15 10.9 4.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDJ66556.1 - 0.23 9.6 12.4 0.26 9.4 8.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Androgen_recep PF02166.11 CDJ66556.1 - 2.3 6.9 7.3 3.3 6.4 5.0 1.1 1 0 0 1 1 1 0 Androgen receptor MutS_V PF00488.16 CDJ66557.1 - 1.8e-08 34.1 0.1 3.1e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 MutS domain V Gaa1 PF04114.9 CDJ66557.1 - 0.1 11.2 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF663 PF04950.7 CDJ66559.1 - 0.037 12.9 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF663) ATG27 PF09451.5 CDJ66561.1 - 0.039 13.1 2.1 0.088 12.0 1.5 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 Glt_symporter PF03616.9 CDJ66561.1 - 0.2 10.1 0.8 1.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Sodium/glutamate symporter RbsD_FucU PF05025.8 CDJ66561.1 - 3.5 7.9 13.1 1.1 9.5 2.4 3.2 2 1 0 2 2 2 0 RbsD / FucU transport protein family Coatomer_E PF04733.9 CDJ66565.1 - 8.3e-13 48.1 2.7 1.5e-12 47.3 1.8 1.4 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_11 PF13414.1 CDJ66565.1 - 0.00023 20.7 0.1 0.00023 20.7 0.0 2.8 2 1 1 3 3 3 1 TPR repeat Alkyl_sulf_dimr PF14863.1 CDJ66565.1 - 0.0061 16.7 1.1 0.026 14.7 0.0 2.3 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_7 PF13176.1 CDJ66565.1 - 0.009 15.7 1.9 0.069 12.9 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ66565.1 - 0.06 14.0 0.1 0.06 14.0 0.1 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat EIIC-GAT PF03611.9 CDJ66566.1 - 0.89 8.2 0.9 2 7.1 0.6 1.5 1 0 0 1 1 1 0 PTS system sugar-specific permease component DUF342 PF03961.8 CDJ66567.1 - 5.6 5.2 8.9 3.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Peptidase_M56 PF05569.6 CDJ66572.1 - 0.07 12.0 0.3 0.12 11.2 0.1 1.5 1 1 0 1 1 1 0 BlaR1 peptidase M56 SR-25 PF10500.4 CDJ66572.1 - 2.9 7.2 39.5 1.5 8.2 9.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mucin PF01456.12 CDJ66572.1 - 5.2 6.8 9.8 3.6 7.3 0.8 2.4 2 1 0 2 2 2 0 Mucin-like glycoprotein DUF2413 PF10310.4 CDJ66572.1 - 9.5 4.9 39.0 0.0089 14.8 7.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) SOG2 PF10428.4 CDJ66573.1 - 1.4 7.5 26.6 1.5 7.4 18.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_60s PF00428.14 CDJ66573.1 - 4.4 7.7 8.6 11 6.4 6.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein SpaB_C PF14028.1 CDJ66574.1 - 0.038 13.5 8.3 0.047 13.2 5.8 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain Sec63 PF02889.11 CDJ66575.1 - 1.3e-12 47.6 0.1 3e-08 33.2 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.26 CDJ66575.1 - 7.2e-11 41.7 0.0 1.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDJ66575.1 - 4.2e-05 23.1 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HHH_5 PF14520.1 CDJ66575.1 - 5.8e-05 23.1 0.3 0.00028 20.9 0.2 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 CDJ66575.1 - 6.3e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_60s PF00428.14 CDJ66575.1 - 0.0045 17.3 3.6 0.0045 17.3 2.5 8.9 6 1 1 7 7 7 4 60s Acidic ribosomal protein KAP_NTPase PF07693.9 CDJ66575.1 - 0.26 10.2 1.4 0.62 8.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain IPK PF03770.11 CDJ66576.1 - 0.035 13.7 0.0 0.069 12.7 0.0 1.4 1 1 0 1 1 1 0 Inositol polyphosphate kinase DUF2644 PF10841.3 CDJ66576.1 - 0.072 13.1 0.7 0.21 11.6 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) FabA PF07977.8 CDJ66577.1 - 1.2e-31 109.0 0.0 1.5e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain Med15 PF09606.5 CDJ66578.1 - 0.0011 17.2 54.2 0.0016 16.7 37.6 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ66578.1 - 5 5.2 44.2 5.6 5.0 30.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDJ66579.1 - 0.0088 15.7 4.1 0.011 15.4 2.8 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ66579.1 - 0.0096 14.2 10.6 0.012 13.9 7.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 CDJ66579.1 - 0.016 14.5 2.6 0.021 14.2 1.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.1 CDJ66579.1 - 0.74 8.7 4.3 1 8.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FCP1_C PF09309.5 CDJ66579.1 - 0.91 8.7 7.6 1.5 8.0 5.3 1.2 1 0 0 1 1 1 0 FCP1, C-terminal FimP PF09766.4 CDJ66579.1 - 1.8 7.5 15.3 2.5 7.0 10.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein RRP14 PF15459.1 CDJ66579.1 - 2 8.5 12.6 2e+02 2.1 10.1 2.8 4 0 0 4 4 4 0 60S ribosome biogenesis protein Rrp14 Pex14_N PF04695.8 CDJ66579.1 - 2 8.4 9.9 3.4 7.7 6.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EF-hand_1 PF00036.27 CDJ66580.1 - 6.7e-32 106.3 4.6 3.1e-08 32.3 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDJ66580.1 - 3.8e-27 94.2 0.4 2.9e-12 46.5 0.1 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDJ66580.1 - 6.2e-25 84.8 0.4 3.7e-07 29.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CDJ66580.1 - 4.8e-24 82.5 4.3 3.6e-07 29.2 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CDJ66580.1 - 1.5e-20 72.5 8.8 2.3e-07 30.3 0.1 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CDJ66580.1 - 9.6e-08 31.7 1.5 0.0016 18.1 0.0 2.9 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CDJ66580.1 - 8.1e-06 25.8 0.0 0.022 14.7 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CDJ66580.1 - 0.00018 21.3 0.0 0.0092 15.8 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain DUF2267 PF10025.4 CDJ66580.1 - 0.0045 17.0 0.0 0.044 13.8 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2267) TerB PF05099.8 CDJ66580.1 - 0.039 13.6 0.1 0.29 10.8 0.0 2.1 1 1 2 3 3 3 0 Tellurite resistance protein TerB Dockerin_1 PF00404.13 CDJ66580.1 - 4 7.3 7.5 6.3 6.6 0.4 3.3 3 0 0 3 3 3 0 Dockerin type I repeat SgrR_N PF12793.2 CDJ66581.1 - 0.74 9.8 5.5 0.14 12.1 0.8 1.8 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term TFIIA PF03153.8 CDJ66581.1 - 6 6.6 10.0 7.8 6.2 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ66581.1 - 7.3 4.6 13.8 8.9 4.4 9.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Helicase_C PF00271.26 CDJ66582.1 - 3.5e-08 33.2 0.0 3.5e-08 33.2 0.0 4.0 5 0 0 5 5 5 1 Helicase conserved C-terminal domain SR-25 PF10500.4 CDJ66583.1 - 0.00064 19.2 17.5 0.00064 19.2 12.1 5.8 3 2 3 6 6 6 1 Nuclear RNA-splicing-associated protein Cyclin_C PF02984.14 CDJ66583.1 - 0.0035 17.2 0.1 0.0035 17.2 0.1 4.2 3 1 0 3 3 3 1 Cyclin, C-terminal domain FimP PF09766.4 CDJ66584.1 - 0.0037 16.3 0.6 0.0047 16.0 0.4 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF1645 PF07816.6 CDJ66584.1 - 0.0043 17.5 10.1 0.0043 17.5 7.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1645) FimP PF09766.4 CDJ66585.1 - 0.0018 17.3 17.5 0.021 13.8 5.8 2.1 2 0 0 2 2 2 2 Fms-interacting protein Spt20 PF12090.3 CDJ66585.1 - 0.0072 15.6 10.7 0.15 11.3 1.5 2.3 2 0 0 2 2 2 2 Spt20 family Pex16 PF08610.5 CDJ66585.1 - 0.0081 15.1 6.1 0.0081 15.1 4.3 2.2 2 0 0 2 2 2 1 Peroxisomal membrane protein (Pex16) SR-25 PF10500.4 CDJ66585.1 - 0.063 12.7 40.7 0.13 11.7 7.2 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4207 PF13904.1 CDJ66585.1 - 0.063 12.6 32.0 0.17 11.2 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) CAF-1_p150 PF11600.3 CDJ66585.1 - 0.1 11.9 23.6 0.37 10.1 6.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAB3GAP2_N PF14655.1 CDJ66585.1 - 0.1 11.5 16.6 0.16 10.9 2.5 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Band_3_cyto PF07565.8 CDJ66585.1 - 0.23 10.9 10.1 1.2 8.5 2.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PH_4 PF15404.1 CDJ66585.1 - 0.39 10.2 9.2 0.6 9.6 2.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain EPL1 PF10513.4 CDJ66585.1 - 0.53 10.5 10.9 1.8 8.8 2.4 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like AUX_IAA PF02309.11 CDJ66585.1 - 0.58 9.8 13.3 1.8 8.2 2.4 2.2 2 0 0 2 2 2 0 AUX/IAA family DUF3464 PF11947.3 CDJ66585.1 - 0.85 9.0 11.9 1.1 8.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DivIC PF04977.10 CDJ66585.1 - 1.3 8.5 20.4 0.82 9.2 1.7 2.2 2 0 0 2 2 2 0 Septum formation initiator Bud13 PF09736.4 CDJ66585.1 - 1.5 9.0 16.4 4.8 7.4 0.3 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex SicP-binding PF09119.5 CDJ66585.1 - 1.5 8.5 4.5 0.35 10.5 0.2 2.0 2 0 0 2 2 2 0 SicP binding DUF4557 PF15101.1 CDJ66585.1 - 1.7 8.4 23.4 0.61 9.8 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) FAM176 PF14851.1 CDJ66585.1 - 2.3 7.8 6.1 0.93 9.1 0.9 2.3 2 0 0 2 2 2 0 FAM176 family DUF3408 PF11888.3 CDJ66585.1 - 2.4 8.0 11.6 2.2 8.2 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) TFIIA PF03153.8 CDJ66585.1 - 3.1 7.5 36.0 5.2 6.8 25.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.5 CDJ66585.1 - 3.3 7.5 9.9 8.1 6.2 3.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF912 PF06024.7 CDJ66585.1 - 3.3 7.8 7.8 2.8 8.0 0.8 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1764 PF08576.5 CDJ66585.1 - 4.4 8.1 15.0 14 6.5 5.3 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF3801 PF12687.2 CDJ66585.1 - 9.1 5.7 15.3 4.8 6.6 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Ribosomal_60s PF00428.14 CDJ66587.1 - 0.076 13.4 7.3 2 8.8 3.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein BPD_transp_2 PF02653.11 CDJ66587.1 - 0.88 8.4 8.7 1.2 7.9 6.1 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Pkinase PF00069.20 CDJ66588.1 - 4.7e-28 98.0 0.0 4.3e-27 94.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ66588.1 - 1.1e-17 63.9 0.0 2e-14 53.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDJ66588.1 - 0.04 13.6 10.1 0.27 10.9 7.0 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF605 PF04652.11 CDJ66589.1 - 0.073 12.4 27.1 0.073 12.4 18.8 1.1 1 0 0 1 1 1 0 Vta1 like BUD22 PF09073.5 CDJ66589.1 - 0.11 11.6 43.4 0.13 11.2 30.1 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 CDJ66589.1 - 0.15 10.5 26.5 0.18 10.2 18.4 1.0 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 CDJ66589.1 - 0.81 7.7 21.4 0.81 7.7 14.8 1.1 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 CDJ66589.1 - 5.4 6.1 28.1 6.9 5.7 19.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.6 CDJ66590.1 - 0.0079 16.0 16.8 0.013 15.3 11.7 1.3 1 0 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region ArgK PF03308.11 CDJ66590.1 - 1.3 7.7 5.2 1.3 7.6 2.6 1.6 1 1 0 1 1 1 0 ArgK protein Cytochrom_NNT PF03264.9 CDJ66590.1 - 2.4 7.5 5.7 5.6 6.3 3.8 1.9 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DUF342 PF03961.8 CDJ66590.1 - 5.3 5.3 15.9 7.2 4.8 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 CDJ66590.1 - 10 5.2 13.7 12 4.9 9.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LRR19-TM PF15176.1 CDJ66591.1 - 0.011 15.4 0.0 0.037 13.7 0.0 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Ion_trans PF00520.26 CDJ66591.1 - 0.25 10.5 0.0 0.44 9.7 0.0 1.3 1 0 0 1 1 1 0 Ion transport protein GCC2_GCC3 PF07699.8 CDJ66592.1 - 0.0076 15.8 0.1 0.022 14.3 0.1 1.8 1 0 0 1 1 1 1 GCC2 and GCC3 Notch PF00066.12 CDJ66592.1 - 0.47 10.7 3.0 0.48 10.7 0.5 2.0 2 0 0 2 2 2 0 LNR domain Lustrin_cystein PF14625.1 CDJ66593.1 - 2 8.5 78.6 0.2 11.7 1.9 10.0 3 3 7 10 10 10 0 Lustrin, cysteine-rich repeated domain GCC2_GCC3 PF07699.8 CDJ66594.1 - 4.4e-06 26.1 35.5 0.00042 19.8 6.5 4.7 2 2 2 5 5 5 4 GCC2 and GCC3 NCD3G PF07562.9 CDJ66594.1 - 0.0022 17.6 23.1 0.012 15.2 2.9 4.6 3 3 1 4 4 4 3 Nine Cysteines Domain of family 3 GPCR Lustrin_cystein PF14625.1 CDJ66594.1 - 0.052 13.6 40.3 0.81 9.8 0.7 6.4 1 1 5 6 6 6 0 Lustrin, cysteine-rich repeated domain NHL PF01436.16 CDJ66595.1 - 4.3e-16 57.9 0.5 1.2e-05 24.9 0.0 3.9 4 0 0 4 4 4 3 NHL repeat SGL PF08450.7 CDJ66595.1 - 0.00013 21.4 0.5 0.081 12.2 0.0 3.2 2 1 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 CDJ66595.1 - 0.05 13.5 1.0 0.53 10.3 0.0 2.8 4 0 0 4 4 4 0 Arylesterase Lustrin_cystein PF14625.1 CDJ66596.1 - 5 7.2 23.5 7.2 6.7 6.4 3.3 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain GCC2_GCC3 PF07699.8 CDJ66597.1 - 0.0038 16.7 9.5 0.078 12.5 5.1 2.4 1 1 1 2 2 2 2 GCC2 and GCC3 NCD3G PF07562.9 CDJ66597.1 - 0.65 9.7 6.0 2.4 7.9 0.5 2.4 1 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR GCC2_GCC3 PF07699.8 CDJ66598.1 - 6e-09 35.3 27.4 7.6e-05 22.2 0.8 4.8 3 1 1 4 4 4 3 GCC2 and GCC3 Lustrin_cystein PF14625.1 CDJ66599.1 - 0.0039 17.2 20.5 0.028 14.4 1.9 3.8 4 0 0 4 4 4 3 Lustrin, cysteine-rich repeated domain GCC2_GCC3 PF07699.8 CDJ66599.1 - 0.1 12.1 15.2 0.79 9.3 2.0 4.2 4 1 1 5 5 5 0 GCC2 and GCC3 Granulin PF00396.13 CDJ66599.1 - 2.5 8.2 17.0 3.5 7.7 0.5 3.9 4 0 0 4 4 4 0 Granulin CBM_19 PF03427.8 CDJ66599.1 - 6.2 6.6 18.2 2.8 7.8 0.1 4.6 3 2 2 5 5 5 0 Carbohydrate binding domain (family 19) FixG_C PF11614.3 CDJ66600.1 - 0.08 13.0 0.0 3.3 7.8 0.0 2.8 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Tctex-1 PF03645.8 CDJ66601.1 - 6e-21 74.1 0.0 7.1e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family MinC_N PF05209.8 CDJ66602.1 - 0.065 12.9 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Dynein_heavy PF03028.10 CDJ66604.1 - 4.8e-11 41.4 0.0 5.3e-11 41.3 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 CDJ66605.1 - 1.5e-58 197.9 0.0 2.8e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CDJ66605.1 - 9.8e-51 171.7 0.4 4.4e-50 169.6 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CDJ66605.1 - 2.4e-45 154.7 0.0 4.3e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDJ66605.1 - 1.2e-14 54.2 0.0 3e-06 27.0 0.0 3.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) MT PF12777.2 CDJ66605.1 - 3.7e-08 32.4 8.5 7.3e-08 31.5 5.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA PF00004.24 CDJ66605.1 - 0.0011 19.1 0.0 0.01 16.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDJ66605.1 - 0.2 11.6 6.9 4.9 7.1 0.1 4.6 4 1 1 5 5 5 0 AAA ATPase domain VIT1 PF01988.14 CDJ66605.1 - 0.31 10.4 3.8 0.59 9.5 2.6 1.4 1 0 0 1 1 1 0 VIT family AAA_6 PF12774.2 CDJ66606.1 - 1.1e-32 113.4 0.0 1.8e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_29 PF13555.1 CDJ66606.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_6 PF12774.2 CDJ66607.1 - 2.9e-47 161.1 0.1 3.9e-47 160.7 0.1 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CDJ66607.1 - 0.0022 17.6 0.0 0.1 12.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CDJ66607.1 - 0.003 17.7 0.0 0.0074 16.4 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CDJ66607.1 - 0.022 14.6 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CDJ66607.1 - 0.026 14.2 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CDJ66607.1 - 0.085 12.4 0.2 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CDJ66607.1 - 0.1 12.7 0.5 0.27 11.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDJ66607.1 - 0.12 13.2 0.0 0.26 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain DHC_N2 PF08393.8 CDJ66608.1 - 4e-98 328.5 8.7 5.5e-98 328.1 6.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 HTH_44 PF14641.1 CDJ66608.1 - 0.015 15.3 0.7 0.14 12.1 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix DNA-binding domain of SPT6 Takusan PF04822.8 CDJ66608.1 - 0.057 13.1 0.2 3.3 7.5 0.0 2.8 2 0 0 2 2 2 0 Takusan RHH_1 PF01402.16 CDJ66608.1 - 0.07 13.0 0.7 0.4 10.6 0.0 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family AKNA PF12443.3 CDJ66609.1 - 0.0068 16.4 0.4 0.0072 16.3 0.3 1.1 1 0 0 1 1 1 1 AT-hook-containing transcription factor Mso1_C PF14477.1 CDJ66609.1 - 0.059 13.6 0.4 0.081 13.2 0.3 1.3 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 DUF3584 PF12128.3 CDJ66609.1 - 0.14 9.4 4.5 0.16 9.2 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HSCB_C PF07743.8 CDJ66609.1 - 0.24 11.9 2.5 0.41 11.1 1.7 1.4 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Snapin_Pallidin PF14712.1 CDJ66610.1 - 0.033 14.5 4.7 2.3 8.5 0.1 2.6 2 0 0 2 2 2 0 Snapin/Pallidin CorA PF01544.13 CDJ66610.1 - 0.32 9.9 3.1 0.5 9.3 2.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2019 PF09450.5 CDJ66610.1 - 0.45 10.4 4.1 0.94 9.3 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2019) Atg14 PF10186.4 CDJ66610.1 - 0.52 9.2 10.0 0.86 8.4 6.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ALMT PF11744.3 CDJ66610.1 - 0.67 8.5 3.4 0.73 8.4 2.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter 60KD_IMP PF02096.15 CDJ66610.1 - 0.95 9.0 5.5 8.2 6.0 0.1 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein HR1 PF02185.11 CDJ66610.1 - 1 9.1 10.5 0.042 13.5 1.8 2.5 2 1 1 3 3 3 0 Hr1 repeat Baculo_PEP_C PF04513.7 CDJ66610.1 - 2.7 7.8 9.4 41 3.9 5.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF641 PF04859.7 CDJ66610.1 - 3.9 7.2 12.6 1.3 8.8 3.2 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) YlqD PF11068.3 CDJ66610.1 - 5.9 6.9 17.0 10 6.1 3.9 2.6 1 1 0 2 2 2 0 YlqD protein DUF883 PF05957.8 CDJ66610.1 - 7.9 6.9 10.7 1.7 9.1 0.8 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 CDJ66610.1 - 8.2 6.4 15.5 3.8 7.5 6.7 2.3 1 1 1 2 2 2 0 DivIVA protein THOC7 PF05615.8 CDJ66610.1 - 8.6 6.6 14.2 3.1 8.0 1.9 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 Nucleoporin_N PF08801.6 CDJ66612.1 - 0.039 12.7 0.0 0.067 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like Filament PF00038.16 CDJ66613.1 - 0.0004 19.9 31.3 0.0004 19.9 21.7 6.2 2 2 2 4 4 4 1 Intermediate filament protein Reo_sigmaC PF04582.7 CDJ66613.1 - 1 8.4 25.4 5.6 6.0 0.1 5.0 3 1 1 5 5 5 0 Reovirus sigma C capsid protein MHC2-interact PF09307.5 CDJ66615.1 - 0.033 13.9 0.1 0.13 12.0 0.1 2.0 1 0 0 1 1 1 0 CLIP, MHC2 interacting Atg14 PF10186.4 CDJ66616.1 - 0.028 13.3 7.3 0.026 13.4 5.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Microtub_assoc PF07989.6 CDJ66616.1 - 0.036 13.8 2.2 0.036 13.8 1.5 2.3 1 1 0 2 2 2 0 Microtubule associated HAUS6_N PF14661.1 CDJ66616.1 - 0.041 13.2 5.4 0.05 12.9 3.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CCDC32 PF14989.1 CDJ66616.1 - 0.052 13.3 4.5 0.068 13.0 3.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing 32 USP8_interact PF08941.5 CDJ66616.1 - 0.059 12.6 6.8 0.02 14.2 2.8 1.5 2 0 0 2 2 2 0 USP8 interacting BOP1NT PF08145.7 CDJ66616.1 - 0.068 12.8 1.3 0.088 12.5 0.9 1.1 1 0 0 1 1 1 0 BOP1NT (NUC169) domain SpoU_sub_bind PF08032.7 CDJ66616.1 - 0.13 12.4 1.2 0.29 11.3 0.3 1.8 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding RBD-FIP PF09457.5 CDJ66616.1 - 0.24 11.2 4.9 1.6 8.5 0.6 3.1 2 1 1 3 3 3 0 FIP domain HALZ PF02183.13 CDJ66616.1 - 0.3 10.8 9.8 2.9 7.6 0.0 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper RmuC PF02646.11 CDJ66616.1 - 6.9 5.4 14.2 12 4.6 5.1 2.0 1 1 1 2 2 2 0 RmuC family TPR_19 PF14559.1 CDJ66617.1 - 3.1e-08 33.8 1.6 0.002 18.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ66617.1 - 1.6e-07 31.3 0.8 0.032 14.8 0.0 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ66617.1 - 4.9e-06 27.0 0.1 0.0014 19.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 CDJ66617.1 - 5.5e-06 25.7 0.8 0.17 11.3 0.0 3.5 3 0 0 3 3 3 2 PPR repeat TPR_2 PF07719.12 CDJ66617.1 - 8.8e-06 25.2 6.9 0.0022 17.7 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ66617.1 - 1.2e-05 25.4 0.6 0.00093 19.5 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ66617.1 - 5.5e-05 23.0 6.7 1 9.3 0.0 5.0 2 1 2 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 CDJ66617.1 - 0.00038 20.2 2.6 0.57 10.2 0.0 4.0 4 0 0 4 4 4 1 PPR repeat TPR_1 PF00515.23 CDJ66617.1 - 0.003 17.0 6.4 0.43 10.2 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDJ66617.1 - 0.0033 17.0 2.3 0.12 12.0 0.2 3.6 2 1 1 3 3 3 1 TPR repeat TPR_10 PF13374.1 CDJ66617.1 - 0.024 14.5 0.6 3.3 7.7 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat nsp7 PF08716.5 CDJ66617.1 - 0.058 13.7 0.0 0.19 12.1 0.0 2.0 1 1 0 1 1 1 0 nsp7 replicase TPR_3 PF07720.7 CDJ66617.1 - 0.11 12.3 3.0 0.25 11.1 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CDJ66617.1 - 1.4 9.1 16.4 0.96 9.6 0.2 4.0 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4006 PF13179.1 CDJ66619.1 - 0.12 11.9 0.2 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF4006) KAR9 PF08580.5 CDJ66621.1 - 0.37 9.0 12.1 0.44 8.7 8.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 POX PF07526.6 CDJ66624.1 - 1.5 9.0 8.0 0.56 10.4 1.7 2.4 2 0 0 2 2 2 0 Associated with HOX Dehydrin PF00257.14 CDJ66624.1 - 1.5 9.0 4.2 0.26 11.6 0.1 1.9 2 1 0 2 2 2 0 Dehydrin AAA_11 PF13086.1 CDJ66626.1 - 9.8e-50 169.3 2.7 9.8e-50 169.3 1.9 8.5 5 3 1 6 6 6 1 AAA domain AAA_12 PF13087.1 CDJ66626.1 - 1e-46 158.8 1.4 1e-45 155.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CDJ66626.1 - 5.1e-11 42.1 7.9 5.1e-11 42.1 5.5 6.1 5 1 0 5 5 5 1 Part of AAA domain AAA PF00004.24 CDJ66626.1 - 0.53 10.4 3.5 0.26 11.4 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) His_Phos_1 PF00300.17 CDJ66627.1 - 2.5e-11 43.9 0.0 1.5e-10 41.3 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SYF2 PF08231.7 CDJ66628.1 - 3.4e-36 124.6 2.3 3.4e-36 124.6 1.6 3.8 2 2 1 3 3 3 1 SYF2 splicing factor Pro_isomerase PF00160.16 CDJ66628.1 - 1.6e-34 119.3 0.0 3.1e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2944 PF11161.3 CDJ66628.1 - 0.15 11.7 1.8 0.18 11.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Ribosomal_L3 PF00297.17 CDJ66629.1 - 7.2e-23 81.3 0.1 4.9e-21 75.3 0.1 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 ubiquitin PF00240.18 CDJ66630.1 - 2.3e-06 26.9 0.0 5.4e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 CDJ66630.1 - 0.001 18.7 0.0 0.0081 15.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF237 PF03072.9 CDJ66630.1 - 0.067 13.1 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 MG032/MG096/MG288 family 1 Exosortase_EpsH PF09721.5 CDJ66630.1 - 0.11 11.7 2.9 0.14 11.3 2.0 1.1 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) AF-4 PF05110.8 CDJ66631.1 - 0.029 12.2 10.5 0.035 11.9 7.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.4 CDJ66631.1 - 0.057 12.8 15.6 0.074 12.5 10.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mif2_N PF15624.1 CDJ66631.1 - 1.8 9.1 5.3 2.5 8.6 3.7 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal XAP5 PF04921.9 CDJ66631.1 - 5.1 6.6 8.4 6.3 6.2 5.8 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF572 PF04502.8 CDJ66631.1 - 6.6 5.8 11.6 8.6 5.4 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_DNAp_acc PF04929.7 CDJ66631.1 - 7.9 5.3 6.9 10 4.9 4.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CDC45 PF02724.9 CDJ66631.1 - 8.5 4.2 14.3 12 3.8 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2031 PF09592.5 CDJ66632.1 - 0.045 12.8 7.7 0.077 12.1 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) SR-25 PF10500.4 CDJ66633.1 - 9.3 5.6 14.3 18 4.6 0.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein LSM PF01423.17 CDJ66634.1 - 2.5e-17 62.1 0.1 2.8e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain MMS22L_C PF14911.1 CDJ66634.1 - 0.039 13.0 0.0 0.04 12.9 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal WD40 PF00400.27 CDJ66636.1 - 3.2e-08 33.1 1.3 0.0035 17.1 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CDJ66636.1 - 0.015 14.7 0.1 0.044 13.2 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CAF1 PF04857.15 CDJ66637.1 - 1.5e-20 73.6 0.6 2.4e-19 69.6 0.4 2.7 1 1 0 1 1 1 1 CAF1 family ribonuclease DUF755 PF05501.6 CDJ66637.1 - 0.0074 16.3 21.4 0.0074 16.3 14.8 5.2 3 1 2 5 5 5 2 Domain of unknown function (DUF755) FB_lectin PF07367.6 CDJ66637.1 - 0.12 12.0 0.3 0.28 10.7 0.2 1.6 1 0 0 1 1 1 0 Fungal fruit body lectin Macoilin PF09726.4 CDJ66637.1 - 0.56 8.4 53.5 0.057 11.7 15.2 2.2 2 0 0 2 2 2 0 Transmembrane protein DUF572 PF04502.8 CDJ66637.1 - 0.74 8.9 43.7 1.4 8.0 7.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Hid1 PF12722.2 CDJ66637.1 - 0.83 7.2 28.4 0.62 7.6 6.1 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF605 PF04652.11 CDJ66637.1 - 0.97 8.7 41.6 0.064 12.6 6.5 2.3 2 0 0 2 2 2 0 Vta1 like SR-25 PF10500.4 CDJ66642.1 - 0.0017 17.8 2.7 0.0017 17.8 1.8 18.8 18 1 2 20 20 20 7 Nuclear RNA-splicing-associated protein RED_N PF07808.8 CDJ66644.1 - 0.00021 20.5 6.7 0.00021 20.5 4.7 1.6 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF3270 PF11674.3 CDJ66644.1 - 0.001 19.0 2.8 0.0024 17.8 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3270) AIF_C PF14721.1 CDJ66644.1 - 0.0017 18.5 2.0 0.0017 18.5 1.4 2.0 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Abi_2 PF07751.6 CDJ66644.1 - 0.0033 17.6 0.1 0.0042 17.3 0.0 1.1 1 0 0 1 1 1 1 Abi-like protein Folate_carrier PF01770.13 CDJ66644.1 - 0.0068 14.9 0.4 0.0076 14.8 0.3 1.2 1 0 0 1 1 1 1 Reduced folate carrier Ctr PF04145.10 CDJ66644.1 - 0.012 15.7 8.1 0.21 11.6 0.9 2.1 2 0 0 2 2 2 0 Ctr copper transporter family VMA21 PF09446.5 CDJ66644.1 - 0.017 14.9 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 1 0 VMA21-like domain OATP PF03137.15 CDJ66644.1 - 0.021 12.9 0.2 0.021 12.8 0.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PBP1_TM PF14812.1 CDJ66644.1 - 0.035 14.4 0.6 0.035 14.4 0.4 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ndc1_Nup PF09531.5 CDJ66644.1 - 0.058 11.8 0.9 0.055 11.8 0.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BatD PF13584.1 CDJ66644.1 - 0.11 11.1 5.9 0.017 13.7 1.0 1.7 1 1 1 2 2 2 0 Oxygen tolerance Suf PF05843.9 CDJ66644.1 - 0.24 11.0 14.2 0.1 12.2 6.7 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Rho_GDI PF02115.12 CDJ66644.1 - 0.38 10.1 6.3 0.56 9.5 4.4 1.2 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Spt20 PF12090.3 CDJ66644.1 - 0.42 9.9 14.9 0.26 10.6 8.5 1.8 2 0 0 2 2 2 0 Spt20 family PTS_EIIC PF02378.13 CDJ66644.1 - 0.75 8.5 5.1 1.3 7.7 3.5 1.3 1 1 0 1 1 1 0 Phosphotransferase system, EIIC DDHD PF02862.12 CDJ66644.1 - 1.5 8.5 8.9 3 7.5 5.6 1.7 2 0 0 2 2 2 0 DDHD domain DUF3675 PF12428.3 CDJ66644.1 - 2.6 8.3 4.4 1 9.6 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Serinc PF03348.10 CDJ66644.1 - 3.5 6.2 9.9 0.71 8.5 4.5 1.5 1 1 1 2 2 2 0 Serine incorporator (Serinc) Glyco_transf_15 PF01793.11 CDJ66644.1 - 6 5.7 7.3 10 4.9 5.1 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF912 PF06024.7 CDJ66644.1 - 6.5 6.8 7.8 0.45 10.5 0.9 2.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CDC45 PF02724.9 CDJ66644.1 - 8.1 4.3 10.7 13 3.6 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1027 PF06265.6 CDJ66645.1 - 0.057 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) RAP1 PF07218.6 CDJ66645.1 - 3.7 5.5 11.0 4.7 5.1 7.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Fmp27_WPPW PF10359.4 CDJ66645.1 - 4.6 5.5 13.8 0.25 9.7 0.9 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF572 PF04502.8 CDJ66645.1 - 4.7 6.3 21.6 3.1 6.9 4.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) SR-25 PF10500.4 CDJ66645.1 - 7.3 5.9 37.6 0.072 12.5 12.0 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribonuc_red_sm PF00268.16 CDJ66647.1 - 2.7e-81 272.6 0.0 3.2e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Surface_antigen PF11054.3 CDJ66648.1 - 2.4e-79 266.3 1.3 2.8e-79 266.1 0.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ66649.1 - 2.1e-96 322.2 2.1 2.4e-96 322.0 1.5 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Aminotran_1_2 PF00155.16 CDJ66650.1 - 2.6e-15 56.2 0.6 1.8e-14 53.4 0.4 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II SR-25 PF10500.4 CDJ66650.1 - 0.00078 18.9 18.4 0.0021 17.5 1.7 3.3 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDJ66650.1 - 0.039 14.3 6.4 0.14 12.5 3.7 2.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein Rrp15p PF07890.7 CDJ66650.1 - 0.094 12.7 3.7 0.54 10.3 0.1 2.5 2 0 0 2 2 2 0 Rrp15p DUF3357 PF11837.3 CDJ66652.1 - 0.061 13.1 0.1 0.49 10.2 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Myc_target_1 PF15179.1 CDJ66652.1 - 0.14 11.7 2.0 0.84 9.1 0.1 2.8 3 0 0 3 3 3 0 Myc target protein 1 Ribosomal_60s PF00428.14 CDJ66652.1 - 0.26 11.7 30.2 0.17 12.2 1.0 4.7 5 0 0 5 5 5 0 60s Acidic ribosomal protein 7tm_1 PF00001.16 CDJ66652.1 - 0.38 9.8 5.2 0.17 11.0 0.7 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) FHIPEP PF00771.15 CDJ66652.1 - 0.72 8.1 2.0 1.2 7.3 1.0 1.5 1 1 1 2 2 2 0 FHIPEP family Cytochrom_C PF00034.16 CDJ66653.1 - 1.1e-10 42.2 0.1 1.6e-10 41.6 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CDJ66653.1 - 3.9e-06 26.9 3.2 1e-05 25.6 2.2 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CDJ66653.1 - 0.0027 17.1 0.1 0.008 15.6 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c-550 domain Haem_bd PF14376.1 CDJ66653.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Haem-binding domain Ferrochelatase PF00762.14 CDJ66655.1 - 4.6e-67 226.2 0.0 1.6e-66 224.4 0.0 1.8 1 1 0 1 1 1 1 Ferrochelatase UPF0449 PF15136.1 CDJ66655.1 - 8 6.7 8.2 10 6.3 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Kinesin PF00225.18 CDJ66656.1 - 6e-105 350.6 0.2 9.1e-105 350.0 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain TruB_N PF01509.13 CDJ66657.1 - 2.6e-25 89.3 0.9 2e-22 79.9 0.6 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.7 CDJ66657.1 - 1.4e-24 85.7 0.0 3e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 DKCLD (NUC011) domain PUA PF01472.15 CDJ66657.1 - 5.1e-21 74.1 0.9 9.4e-21 73.3 0.6 1.5 1 0 0 1 1 1 1 PUA domain DUF1732 PF08340.6 CDJ66658.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Thioredoxin PF00085.15 CDJ66660.1 - 2e-08 33.8 0.0 4.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Evr1_Alr PF04777.8 CDJ66660.1 - 1.2e-06 28.2 0.9 0.12 12.3 0.0 3.5 3 0 0 3 3 3 2 Erv1 / Alr family Thioredoxin_7 PF13899.1 CDJ66660.1 - 0.0042 17.0 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CDJ66660.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family DUF35_N PF12172.3 CDJ66660.1 - 0.75 9.7 8.4 0.64 9.9 1.3 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_Tnp_IS1595 PF12760.2 CDJ66660.1 - 1.9 8.3 8.5 1.1 9.1 0.5 3.7 4 0 0 4 4 4 0 Transposase zinc-ribbon domain CTDII PF01556.13 CDJ66662.1 - 9.6e-32 108.7 1.2 1.6e-27 95.1 0.5 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 CDJ66662.1 - 4.2e-24 84.0 1.3 7.8e-24 83.1 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CDJ66662.1 - 0.0095 15.9 3.7 0.02 14.9 2.5 1.5 1 0 0 1 1 1 1 DnaJ central domain VPS9 PF02204.13 CDJ66663.1 - 0.0022 17.9 0.1 0.0049 16.8 0.0 1.6 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SDF PF00375.13 CDJ66664.1 - 0.062 12.0 0.0 0.063 12.0 0.0 1.0 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family PAT1 PF09770.4 CDJ66665.1 - 0.1 10.8 64.6 0.12 10.5 44.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Draxin PF15550.1 CDJ66665.1 - 4.3 6.9 35.6 5.5 6.5 24.7 1.1 1 0 0 1 1 1 0 Draxin PLDc PF00614.17 CDJ66666.1 - 3.4e-06 26.6 0.2 7.9e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Phospholipase D Active site motif PLDc_2 PF13091.1 CDJ66666.1 - 0.0001 22.0 0.0 0.0004 20.1 0.0 1.7 1 1 0 1 1 1 1 PLD-like domain Shadoo PF14999.1 CDJ66666.1 - 1.4 8.7 21.5 1.2 8.9 6.1 2.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SR-25 PF10500.4 CDJ66666.1 - 3.5 7.0 23.1 0.35 10.3 11.5 2.1 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Rabaptin PF03528.10 CDJ66666.1 - 6.5 6.7 13.1 1.3 8.9 2.4 2.3 2 0 0 2 2 2 0 Rabaptin DAGAT PF03982.8 CDJ66667.1 - 1e-61 208.2 0.0 1.5e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Tetraspannin PF00335.15 CDJ66667.1 - 0.087 12.0 7.2 0.24 10.6 5.0 1.8 1 0 0 1 1 1 0 Tetraspanin family FHIPEP PF00771.15 CDJ66667.1 - 0.36 9.0 9.5 0.59 8.3 6.6 1.2 1 0 0 1 1 1 0 FHIPEP family Phostensin_N PF13916.1 CDJ66667.1 - 6.1 6.9 15.1 0.92 9.5 3.7 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Utp14 PF04615.8 CDJ66667.1 - 8.8 4.3 22.1 14 3.7 15.3 1.2 1 0 0 1 1 1 0 Utp14 protein RRM_5 PF13893.1 CDJ66668.1 - 5.1e-24 83.8 0.2 7.1e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ66668.1 - 5.9e-22 77.0 0.2 3.9e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ66668.1 - 2.6e-14 52.9 0.1 6.9e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDJ66668.1 - 0.00038 20.1 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CDJ66668.1 - 0.011 15.5 2.7 2.5 8.0 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif Calcipressin PF04847.7 CDJ66668.1 - 0.05 13.1 5.4 0.13 11.8 0.0 3.1 3 0 0 3 3 3 0 Calcipressin GAGA_bind PF06217.7 CDJ66669.1 - 1.6e-05 25.0 1.6 2.5e-05 24.3 1.1 1.3 1 0 0 1 1 1 1 GAGA binding protein-like family DUF2890 PF11081.3 CDJ66669.1 - 0.066 13.2 9.3 0.079 13.0 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ycf1 PF05758.7 CDJ66669.1 - 1 6.9 2.7 0.88 7.2 1.8 1.1 1 0 0 1 1 1 0 Ycf1 Laps PF10169.4 CDJ66669.1 - 5.2 7.3 16.1 8.5 6.6 11.1 1.3 1 0 0 1 1 1 0 Learning-associated protein Atrophin-1 PF03154.10 CDJ66669.1 - 5.7 4.9 11.7 7.1 4.6 8.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family RIO1 PF01163.17 CDJ66671.1 - 8e-47 159.0 0.3 1.2e-46 158.4 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CDJ66671.1 - 7.4e-33 112.4 0.6 1.7e-32 111.2 0.4 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CDJ66671.1 - 1.1e-08 35.1 6.2 5.9e-05 22.9 0.3 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CDJ66671.1 - 1.8e-07 30.4 0.3 3.5e-06 26.2 0.2 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CDJ66671.1 - 0.0095 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Nop14 PF04147.7 CDJ66671.1 - 0.39 8.5 19.6 0.43 8.4 12.1 1.8 2 0 0 2 2 2 0 Nop14-like family DNA_pol_viral_N PF00242.12 CDJ66671.1 - 1.2 8.1 6.3 1.7 7.6 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF1510 PF07423.6 CDJ66671.1 - 1.3 8.3 15.4 1.8 7.9 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDJ66671.1 - 6.6 4.2 6.6 8.8 3.8 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1803 PF08820.5 CDJ66672.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) Glutaredoxin PF00462.19 CDJ66673.1 - 5.7e-17 61.4 0.0 8.3e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 CDJ66673.1 - 5.2e-05 22.8 0.0 6.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CDJ66673.1 - 0.0003 20.5 0.2 0.00082 19.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.1 CDJ66673.1 - 0.0092 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 CDJ66673.1 - 0.013 15.7 0.5 0.046 13.9 0.3 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 CDJ66673.1 - 0.02 15.1 0.1 0.031 14.5 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) OTT_1508_deam PF14441.1 CDJ66673.1 - 0.044 13.5 0.1 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 OTT_1508-like deaminase DUF535 PF04393.8 CDJ66673.1 - 0.056 12.3 0.0 0.067 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF535) Thioredoxin_4 PF13462.1 CDJ66673.1 - 0.072 13.0 0.7 7.1 6.6 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin FANCL_C PF11793.3 CDJ66673.1 - 0.1 12.5 0.0 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain DEAD PF00270.24 CDJ66674.1 - 1.8e-36 125.1 2.8 1.8e-35 121.9 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ66674.1 - 2.5e-14 52.8 1.1 5.1e-06 26.2 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF4217 PF13959.1 CDJ66674.1 - 3.8e-10 39.1 0.0 8.3e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) IMS PF00817.15 CDJ66675.1 - 1.2e-30 106.2 0.0 2.6e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CDJ66675.1 - 0.0056 16.6 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 CDJ66675.1 - 0.35 11.0 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ycf1 PF05758.7 CDJ66675.1 - 3.3 5.3 25.1 5.6 4.5 17.4 1.2 1 0 0 1 1 1 0 Ycf1 LMBR1 PF04791.11 CDJ66675.1 - 3.8 5.9 5.7 7.5 5.0 3.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein ATP-synt_10 PF05176.9 CDJ66676.1 - 0.051 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 ATP10 protein Ashwin PF15323.1 CDJ66677.1 - 0.081 12.9 0.9 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 Developmental protein Corona_nucleoca PF00937.13 CDJ66677.1 - 0.16 10.8 3.9 0.2 10.5 2.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Period_C PF12114.3 CDJ66677.1 - 0.71 9.4 7.8 1 8.9 5.4 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 CDJ66677.1 - 2.7 6.1 10.0 3.2 5.9 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 CDJ66679.1 - 0.0011 18.5 3.7 0.0011 18.5 2.6 2.9 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein U1snRNP70_N PF12220.3 CDJ66680.1 - 0.03 14.6 5.6 0.12 12.6 0.4 2.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SR-25 PF10500.4 CDJ66680.1 - 0.81 9.1 16.5 0.049 13.0 7.6 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein T2SF PF00482.18 CDJ66680.1 - 3 7.7 5.3 1.2 9.0 0.5 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Phostensin_N PF13916.1 CDJ66680.1 - 4.1 7.4 13.5 3.1 7.8 0.9 2.5 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Presenilin PF01080.12 CDJ66680.1 - 4.7 5.9 5.5 6.4 5.4 3.8 1.2 1 0 0 1 1 1 0 Presenilin Gar1 PF04410.9 CDJ66681.1 - 2.5e-12 46.4 3.2 9.2e-12 44.6 2.2 1.9 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF4557 PF15101.1 CDJ66681.1 - 0.11 12.3 10.8 0.16 11.8 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Med15 PF09606.5 CDJ66681.1 - 0.11 10.6 30.1 0.13 10.4 20.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S15 PF02129.13 CDJ66681.1 - 0.16 11.3 2.9 0.2 11.0 2.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SprA-related PF12118.3 CDJ66681.1 - 0.24 10.7 18.6 0.31 10.3 12.9 1.1 1 0 0 1 1 1 0 SprA-related family DUF1943 PF09172.6 CDJ66681.1 - 0.24 10.2 6.0 0.32 9.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) TMEM247 PF15444.1 CDJ66681.1 - 0.31 10.8 5.1 0.43 10.3 3.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 DUF1631 PF07793.6 CDJ66681.1 - 0.35 8.9 16.5 0.42 8.6 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Exonuc_VII_L PF02601.10 CDJ66681.1 - 0.35 9.9 5.8 0.41 9.7 4.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAP_central PF04928.12 CDJ66681.1 - 0.74 8.5 5.3 1 8.1 3.6 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain PAT1 PF09770.4 CDJ66681.1 - 0.91 7.6 22.9 1.1 7.4 15.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MSP1b PF03429.8 CDJ66681.1 - 1.8 6.3 10.6 2.7 5.7 7.3 1.2 1 0 0 1 1 1 0 Major surface protein 1B ChAPs PF09295.5 CDJ66681.1 - 2.2 6.9 4.5 2.8 6.6 3.2 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) AAA_23 PF13476.1 CDJ66681.1 - 2.9 8.1 9.7 3.4 7.9 6.7 1.2 1 0 0 1 1 1 0 AAA domain DOR PF14839.1 CDJ66681.1 - 4.3 7.0 11.7 5.4 6.7 8.1 1.2 1 0 0 1 1 1 0 DOR family RED_N PF07808.8 CDJ66681.1 - 4.7 6.3 11.4 7.4 5.7 7.9 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region Gastrin PF00918.12 CDJ66681.1 - 5.9 7.7 13.0 12 6.7 9.0 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Proteasom_Rpn13 PF04683.8 CDJ66682.1 - 0.02 14.9 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor Adaptin_N PF01602.15 CDJ66683.1 - 0.055 11.7 0.1 0.06 11.6 0.1 1.0 1 0 0 1 1 1 0 Adaptin N terminal region DUF4349 PF14257.1 CDJ66683.1 - 1.1 8.4 10.2 1.2 8.2 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Opi1 PF08618.5 CDJ66683.1 - 1.2 7.9 7.9 1.2 7.9 5.5 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 DUF1176 PF06674.6 CDJ66683.1 - 2.7 7.0 9.3 3 6.8 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) APH PF01636.18 CDJ66683.1 - 7.3 6.2 8.3 8.2 6.0 5.8 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3306 PF11748.3 CDJ66683.1 - 8.7 7.0 7.2 12 6.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DEC-1_N PF04625.8 CDJ66683.1 - 10 4.7 14.1 10 4.6 9.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4349 PF14257.1 CDJ66684.1 - 0.75 8.9 8.5 1 8.5 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) eIF-4B PF06273.6 CDJ66684.1 - 1.2 7.8 8.0 1.4 7.5 5.6 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF3597 PF12200.3 CDJ66684.1 - 1.7 9.0 5.7 2.4 8.5 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Surface_antigen PF11054.3 CDJ66685.1 - 3.1e-49 167.6 7.4 1.6e-47 162.0 5.2 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Ribosomal_60s PF00428.14 CDJ66686.1 - 0.033 14.6 10.1 0.033 14.6 7.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein APH PF01636.18 CDJ66686.1 - 0.64 9.7 6.4 0.79 9.4 4.4 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family MBOAT PF03062.14 CDJ66688.1 - 2.7e-26 92.4 14.7 3.9e-26 91.9 10.2 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CDJ66688.1 - 0.00043 20.2 4.7 0.0017 18.3 3.3 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF2232 PF09991.4 CDJ66690.1 - 0.013 14.5 3.5 0.016 14.1 2.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Peptidase_S49_N PF08496.5 CDJ66690.1 - 0.022 14.5 10.0 0.026 14.3 7.0 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OATP PF03137.15 CDJ66690.1 - 0.086 10.8 8.5 0.09 10.8 5.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Shadoo PF14999.1 CDJ66690.1 - 0.13 12.1 6.4 0.18 11.6 4.4 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective FimP PF09766.4 CDJ66690.1 - 0.24 10.4 23.7 0.32 10.0 16.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein Serinc PF03348.10 CDJ66690.1 - 0.38 9.4 11.0 0.41 9.2 7.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2370 PF10176.4 CDJ66690.1 - 0.56 9.4 10.1 0.59 9.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Glt_symporter PF03616.9 CDJ66690.1 - 0.57 8.6 3.5 0.72 8.2 2.4 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter Folate_carrier PF01770.13 CDJ66690.1 - 0.84 8.0 7.0 0.86 8.0 4.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier eIF-3_zeta PF05091.7 CDJ66690.1 - 0.88 8.1 17.0 0.89 8.1 11.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.12 CDJ66690.1 - 0.98 9.1 13.6 1 9.0 9.5 1.0 1 0 0 1 1 1 0 DDHD domain DUF3408 PF11888.3 CDJ66690.1 - 1 9.2 11.9 1.4 8.8 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) FAM60A PF15396.1 CDJ66690.1 - 1.1 8.9 8.8 1.2 8.8 6.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Baculo_PP31 PF05311.6 CDJ66690.1 - 1.1 8.4 14.0 1.2 8.3 9.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Nucleoside_tran PF01733.13 CDJ66690.1 - 1.2 8.2 3.5 1.2 8.2 2.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter YppG PF14179.1 CDJ66690.1 - 1.2 9.7 37.4 1.2 9.7 25.9 1.1 1 0 0 1 1 1 0 YppG-like protein Dala_Dala_lig_N PF01820.16 CDJ66690.1 - 1.2 9.4 7.9 1.5 9.1 5.5 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FAM176 PF14851.1 CDJ66690.1 - 1.2 8.7 5.6 1.7 8.2 3.9 1.3 1 0 0 1 1 1 0 FAM176 family DUF1183 PF06682.7 CDJ66690.1 - 1.3 8.6 11.1 1.2 8.6 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4446 PF14584.1 CDJ66690.1 - 1.3 8.8 3.9 1.6 8.5 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4557 PF15101.1 CDJ66690.1 - 1.4 8.7 24.5 1.9 8.2 17.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2215 PF10225.4 CDJ66690.1 - 1.4 8.3 6.9 1.6 8.1 4.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF1764 PF08576.5 CDJ66690.1 - 1.4 9.7 14.2 1.8 9.4 9.8 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) FLO_LFY PF01698.11 CDJ66690.1 - 1.4 7.6 14.4 1.6 7.4 10.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein GAGA_bind PF06217.7 CDJ66690.1 - 1.6 8.6 15.5 1.7 8.5 10.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CPSF100_C PF13299.1 CDJ66690.1 - 1.7 8.8 12.5 1.9 8.6 8.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Gag_spuma PF03276.9 CDJ66690.1 - 1.7 6.8 28.1 1.8 6.7 19.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein RR_TM4-6 PF06459.7 CDJ66690.1 - 1.8 8.3 15.5 1.9 8.2 10.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3381 PF11861.3 CDJ66690.1 - 1.9 7.9 11.5 2.1 7.8 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SAGA-Tad1 PF12767.2 CDJ66690.1 - 2.4 7.7 17.2 2.6 7.6 12.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SID-1_RNA_chan PF13965.1 CDJ66690.1 - 2.7 6.0 6.3 2.8 6.0 4.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pal1 PF08316.6 CDJ66690.1 - 2.9 8.3 10.4 3.5 8.0 7.2 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein SeqA PF03925.8 CDJ66690.1 - 3.1 7.4 12.2 3.5 7.2 8.4 1.2 1 0 0 1 1 1 0 SeqA protein Spc7_N PF15402.1 CDJ66690.1 - 3.4 5.5 17.3 3.7 5.4 12.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Peptidase_S15 PF02129.13 CDJ66690.1 - 3.7 6.8 17.3 4.4 6.6 12.0 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Gastrin PF00918.12 CDJ66690.1 - 3.8 8.3 23.7 4.7 8.0 16.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Paramyxo_ncap PF00973.14 CDJ66690.1 - 4.5 5.8 13.8 5.2 5.6 9.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Suf PF05843.9 CDJ66690.1 - 4.7 6.8 24.2 5.9 6.5 16.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lipoprotein_2 PF00921.12 CDJ66690.1 - 4.8 7.1 20.2 5.8 6.9 14.0 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein Spore_coat_CotO PF14153.1 CDJ66690.1 - 4.9 6.5 23.9 5.7 6.3 16.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PcfK PF14058.1 CDJ66690.1 - 4.9 7.2 18.9 5.9 7.0 13.1 1.2 1 0 0 1 1 1 0 PcfK-like protein DUF1980 PF09323.5 CDJ66690.1 - 5.8 6.6 11.5 7.1 6.3 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Rtf2 PF04641.7 CDJ66690.1 - 6.2 5.9 14.0 6.9 5.7 9.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Peptidase_U57 PF05582.7 CDJ66690.1 - 6.4 5.6 9.8 6.8 5.5 6.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Gti1_Pac2 PF09729.4 CDJ66690.1 - 6.5 6.5 9.6 7.7 6.3 6.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family HemX PF04375.9 CDJ66690.1 - 6.7 5.1 33.2 7.6 5.0 23.0 1.0 1 0 0 1 1 1 0 HemX AUX_IAA PF02309.11 CDJ66690.1 - 6.7 6.3 12.0 7.1 6.3 8.3 1.1 1 0 0 1 1 1 0 AUX/IAA family HA2 PF04408.18 CDJ66690.1 - 6.8 6.7 8.6 11 6.1 6.0 1.4 1 1 0 1 1 1 0 Helicase associated domain (HA2) Paf1 PF03985.8 CDJ66690.1 - 7 5.2 17.9 7.6 5.1 12.4 1.0 1 0 0 1 1 1 0 Paf1 P5-ATPase PF12409.3 CDJ66690.1 - 7.1 6.5 6.6 8.5 6.2 4.6 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter Herpes_DNAp_acc PF04929.7 CDJ66690.1 - 7.3 5.4 14.4 8 5.3 10.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Sec62 PF03839.11 CDJ66690.1 - 7.4 5.9 9.5 7.8 5.8 6.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 PBP1_TM PF14812.1 CDJ66690.1 - 8.5 6.7 7.6 12 6.2 5.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med15 PF09606.5 CDJ66690.1 - 9.1 4.3 57.7 13 3.8 40.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4131 PF13567.1 CDJ66691.1 - 1.1 8.6 6.1 1.1 8.6 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DNA_gyraseA_C PF03989.8 CDJ66694.1 - 0.087 12.1 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller PsbI PF02532.9 CDJ66694.1 - 0.39 10.3 3.4 2.4 7.8 1.6 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) LRR19-TM PF15176.1 CDJ66695.1 - 0.027 14.1 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain zf-C2H2_4 PF13894.1 CDJ66696.1 - 0.068 13.5 0.3 0.068 13.5 0.2 4.2 5 1 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CDJ66696.1 - 8.9 6.8 10.6 25 5.3 0.0 4.2 3 0 0 3 3 3 0 Zinc-finger double domain Herpes_US9 PF06072.6 CDJ66698.1 - 6 6.7 5.8 10 6.0 1.9 3.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Actin PF00022.14 CDJ66699.1 - 1.2e-26 93.0 0.0 4.8e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 Actin NMN_transporter PF04973.7 CDJ66700.1 - 0.025 14.0 1.8 0.032 13.6 1.3 1.1 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Toxin_61 PF15538.1 CDJ66700.1 - 0.55 10.2 4.0 0.89 9.5 2.8 1.3 1 0 0 1 1 1 0 Putative toxin 61 Draxin PF15550.1 CDJ66700.1 - 4.2 6.9 8.5 5.6 6.5 5.9 1.1 1 0 0 1 1 1 0 Draxin EF-hand_8 PF13833.1 CDJ66701.1 - 1.1e-05 24.8 0.2 1.1e-05 24.8 0.1 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CDJ66701.1 - 0.0037 17.3 0.1 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair AAA_11 PF13086.1 CDJ66701.1 - 0.02 14.4 1.6 0.023 14.2 1.1 1.1 1 0 0 1 1 1 0 AAA domain Transpep_BrtH PF14399.1 CDJ66701.1 - 0.024 13.9 1.0 0.027 13.7 0.7 1.1 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase EF-hand_1 PF00036.27 CDJ66701.1 - 0.035 13.3 0.9 0.63 9.4 0.0 2.5 3 0 0 3 3 3 0 EF hand SprA-related PF12118.3 CDJ66701.1 - 0.061 12.6 10.9 0.056 12.7 7.6 1.1 1 0 0 1 1 1 0 SprA-related family BAF1_ABF1 PF04684.8 CDJ66701.1 - 0.063 12.1 8.1 0.054 12.3 5.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RAB3GAP2_N PF14655.1 CDJ66701.1 - 0.071 12.1 2.5 0.068 12.1 1.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Tubulin_2 PF13809.1 CDJ66701.1 - 0.077 11.9 2.1 0.09 11.6 1.4 1.0 1 0 0 1 1 1 0 Tubulin like Peroxin-13_N PF04088.8 CDJ66701.1 - 0.095 12.6 0.4 0.14 12.1 0.3 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region EF-hand_6 PF13405.1 CDJ66701.1 - 0.13 12.1 0.1 19 5.4 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain DUF1707 PF08044.6 CDJ66701.1 - 0.26 11.0 1.8 12 5.7 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1707) CBP4 PF07960.6 CDJ66701.1 - 0.34 10.5 9.7 0.69 9.5 6.7 1.5 1 1 0 1 1 1 0 CBP4 60KD_IMP PF02096.15 CDJ66701.1 - 2.2 7.8 8.0 3 7.4 5.5 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Med15 PF09606.5 CDJ66701.1 - 2.7 6.1 20.2 2.9 5.9 14.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDJ66701.1 - 3.8 7.7 14.8 4.6 7.5 10.3 1.0 1 0 0 1 1 1 0 AAA domain Activator_LAG-3 PF11498.3 CDJ66702.1 - 0.0051 15.6 25.9 0.0065 15.2 17.9 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Gly-zipper_OmpA PF13436.1 CDJ66702.1 - 0.011 15.3 0.6 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF605 PF04652.11 CDJ66702.1 - 0.052 12.9 8.4 0.059 12.7 5.8 1.0 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 CDJ66702.1 - 0.22 11.4 10.8 0.26 11.1 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4483 PF14825.1 CDJ66702.1 - 0.31 10.6 8.1 2.7 7.5 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) DUF2076 PF09849.4 CDJ66702.1 - 0.61 10.1 12.0 0.86 9.6 8.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Folliculin PF11704.3 CDJ66702.1 - 0.79 9.2 3.2 9.3 5.8 0.0 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport UPF0233 PF06781.7 CDJ66702.1 - 0.92 9.1 3.6 7.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF4407 PF14362.1 CDJ66702.1 - 1.4 7.8 6.2 1.8 7.4 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2802 PF10975.3 CDJ66702.1 - 2.3 8.0 17.0 1.8 8.3 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) DUF788 PF05620.6 CDJ66702.1 - 2.5 7.9 8.6 0.34 10.7 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF788) PAT1 PF09770.4 CDJ66702.1 - 2.7 6.1 22.0 2.6 6.1 15.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BRCA2 PF00634.13 CDJ66704.1 - 4.1e-09 35.5 0.0 0.00045 19.4 0.0 2.3 2 0 0 2 2 2 2 BRCA2 repeat BRCA-2_OB1 PF09103.5 CDJ66704.1 - 0.0014 18.3 0.0 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 DUF368 PF04018.8 CDJ66706.1 - 0.16 11.1 1.6 0.29 10.2 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF368) PLRV_ORF5 PF01690.12 CDJ66706.1 - 0.35 9.9 4.7 0.39 9.8 3.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4613 PF15390.1 CDJ66706.1 - 0.41 8.7 8.1 0.49 8.5 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) LMBR1 PF04791.11 CDJ66706.1 - 0.42 9.1 4.3 0.5 8.8 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.4 CDJ66706.1 - 0.49 8.6 21.2 0.69 8.1 14.7 1.2 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 CDJ66706.1 - 2.8 8.2 7.3 3.2 8.0 5.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF572 PF04502.8 CDJ66706.1 - 3.2 6.8 18.9 4.1 6.5 13.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Transformer PF06495.6 CDJ66706.1 - 4 7.2 11.1 5.5 6.8 7.7 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein DUF2146 PF10220.4 CDJ66706.1 - 4.2 5.2 13.7 5.3 4.8 9.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DNA_pol_viral_N PF00242.12 CDJ66706.1 - 5 6.0 14.0 6 5.7 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4551 PF15087.1 CDJ66706.1 - 5.4 5.2 11.6 6.2 5.0 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Peptidase_S64 PF08192.6 CDJ66706.1 - 9 4.4 14.5 12 4.0 10.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 TMEM154 PF15102.1 CDJ66706.1 - 9.3 5.9 12.3 0.26 10.9 3.1 2.1 1 1 0 2 2 2 0 TMEM154 protein family DUF3446 PF11928.3 CDJ66707.1 - 0.045 13.9 6.6 0.075 13.2 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 CDJ66707.1 - 1.1 8.6 14.0 1.7 8.0 9.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDJ66708.1 - 0.13 11.9 3.5 0.16 11.6 2.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ66708.1 - 0.24 10.7 3.9 0.31 10.3 2.7 1.1 1 0 0 1 1 1 0 Spt20 family DivIC PF04977.10 CDJ66708.1 - 0.27 10.7 10.8 0.42 10.1 7.5 1.2 1 0 0 1 1 1 0 Septum formation initiator UL73_N PF12522.3 CDJ66708.1 - 0.47 10.0 6.1 1.1 8.8 4.2 1.7 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal RAB3GAP2_N PF14655.1 CDJ66708.1 - 0.73 8.7 6.5 1 8.3 4.5 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDJ66708.1 - 0.75 8.7 9.6 0.96 8.4 6.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein FLO_LFY PF01698.11 CDJ66708.1 - 7.6 5.2 7.9 10 4.8 5.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Baculo_PP31 PF05311.6 CDJ66708.1 - 7.8 5.6 7.8 10 5.2 5.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Lsm_C PF14894.1 CDJ66709.1 - 0.17 11.4 0.5 0.25 10.8 0.3 1.4 1 0 0 1 1 1 0 Lsm C-terminal CALCOCO1 PF07888.6 CDJ66710.1 - 1.3 7.2 9.1 1.4 7.1 6.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like OmpH PF03938.9 CDJ66710.1 - 3.5 7.5 10.3 3.9 7.3 7.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 CDJ66710.1 - 3.6 7.1 13.1 4.4 6.8 9.1 1.1 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 CDJ66710.1 - 3.7 6.6 18.1 6.3 5.9 12.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) APG6 PF04111.7 CDJ66710.1 - 4.4 6.2 9.6 4.7 6.1 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0242 PF06785.6 CDJ66710.1 - 4.5 5.8 8.8 4.9 5.7 6.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Lge1 PF11488.3 CDJ66710.1 - 4.8 7.4 6.2 7.7 6.7 4.3 1.6 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 bZIP_2 PF07716.10 CDJ66710.1 - 9.9 6.0 16.5 0.12 12.2 2.2 2.4 1 1 0 2 2 2 0 Basic region leucine zipper PBP_like PF12727.2 CDJ66711.1 - 0.28 10.1 7.9 0.018 13.9 1.1 2.3 2 0 0 2 2 2 0 PBP superfamily domain Presenilin PF01080.12 CDJ66711.1 - 1.5 7.5 3.3 2.1 7.0 2.3 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.8 CDJ66711.1 - 2.1 8.3 11.8 0.53 10.3 5.3 2.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RIC3 PF15361.1 CDJ66711.1 - 8.2 6.6 8.8 6.1 7.0 4.4 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Paf67 PF10255.4 CDJ66712.1 - 2.5e-82 276.9 0.0 3.4e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 CDJ66712.1 - 0.00098 18.8 0.0 0.0031 17.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat RVT_1 PF00078.22 CDJ66714.1 - 2e-14 53.4 0.0 3.7e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med15 PF09606.5 CDJ66717.1 - 0.0024 16.1 17.4 0.0026 16.0 12.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ66717.1 - 0.0067 16.1 4.8 0.0075 16.0 3.3 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Raftlin PF15250.1 CDJ66717.1 - 0.025 13.0 2.7 0.03 12.8 1.9 1.0 1 0 0 1 1 1 0 Raftlin Yip1 PF04893.12 CDJ66717.1 - 0.027 13.9 1.3 2.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Yip1 domain Hamartin PF04388.7 CDJ66717.1 - 0.027 13.1 11.8 0.032 12.9 8.2 1.0 1 0 0 1 1 1 0 Hamartin protein PsiA PF06952.6 CDJ66717.1 - 0.041 12.9 5.2 0.069 12.1 3.6 1.3 1 0 0 1 1 1 0 PsiA protein CAF-1_p150 PF11600.3 CDJ66717.1 - 0.054 12.8 9.0 0.07 12.5 6.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2126 PF09899.4 CDJ66717.1 - 0.074 11.0 1.0 0.085 10.8 0.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Spt20 PF12090.3 CDJ66717.1 - 0.089 12.1 1.1 0.084 12.2 0.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF3682 PF12446.3 CDJ66717.1 - 0.52 10.6 27.4 1.2 9.4 19.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) Baculo_PP31 PF05311.6 CDJ66717.1 - 0.55 9.4 5.7 0.64 9.2 3.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) TFIIA PF03153.8 CDJ66717.1 - 1.6 8.5 14.5 1.7 8.4 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FimP PF09766.4 CDJ66717.1 - 3.5 6.6 9.6 4.4 6.2 6.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein DivIC PF04977.10 CDJ66717.1 - 4.7 6.7 11.5 7 6.2 8.0 1.2 1 0 0 1 1 1 0 Septum formation initiator zf-C4H2 PF10146.4 CDJ66717.1 - 5.8 6.8 10.6 9.4 6.1 7.2 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein KfrA_N PF11740.3 CDJ66717.1 - 8 6.9 26.3 3 8.3 13.6 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Fis1_TPR_C PF14853.1 CDJ66718.1 - 4.1e-08 32.9 0.2 4.3e-07 29.7 0.1 2.3 1 1 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CDJ66718.1 - 2.2e-06 26.8 0.0 4.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_11 PF13414.1 CDJ66718.1 - 0.00039 19.9 0.0 0.00073 19.1 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CDJ66718.1 - 0.031 14.1 0.1 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ66718.1 - 0.13 11.8 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.11 CDJ66721.1 - 4.4e-16 58.7 0.3 1.4e-15 57.0 0.2 1.9 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B C2 PF00168.25 CDJ66722.1 - 6.6e-27 93.1 0.1 1.6e-06 27.8 0.0 7.1 7 0 0 7 7 7 5 C2 domain FerI PF08151.7 CDJ66722.1 - 0.048 13.6 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 0 FerI (NUC094) domain zf-RING_2 PF13639.1 CDJ66723.1 - 1.7e-11 43.7 12.3 3e-11 42.9 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CDJ66723.1 - 1.2e-06 28.0 8.2 2e-06 27.3 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDJ66723.1 - 6.8e-05 22.8 8.6 0.00016 21.6 6.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDJ66723.1 - 0.0002 21.2 9.7 0.00036 20.4 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDJ66723.1 - 0.0019 17.9 4.1 0.0043 16.8 2.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CDJ66723.1 - 0.019 14.4 5.2 0.039 13.4 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 CDJ66723.1 - 0.022 14.4 10.5 0.048 13.3 7.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.2 CDJ66723.1 - 0.04 13.9 9.0 0.11 12.5 6.2 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 CDJ66723.1 - 0.068 12.8 5.4 0.13 11.9 3.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CDJ66723.1 - 0.51 10.2 7.9 0.95 9.3 5.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CDJ66723.1 - 1.5 8.8 10.0 5.2 7.1 6.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Pox_A_type_inc PF04508.7 CDJ66724.1 - 2.9 7.9 11.7 0.66 9.9 0.3 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Phosphodiest PF01663.17 CDJ66725.1 - 4.1e-06 26.3 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1525 PF07511.6 CDJ66726.1 - 0.064 13.2 0.2 0.064 13.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1525) cNMP_binding PF00027.24 CDJ66728.1 - 2.2e-26 91.5 0.0 1.1e-16 60.3 0.0 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.24 CDJ66729.1 - 2.2e-59 197.2 0.4 3.4e-20 71.6 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain EF-hand_1 PF00036.27 CDJ66729.1 - 4.1e-07 28.8 0.6 0.076 12.3 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CDJ66729.1 - 2.8e-05 23.6 4.5 0.022 14.3 0.1 4.1 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.1 CDJ66729.1 - 6e-05 22.5 0.5 0.82 9.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CDJ66729.1 - 0.00079 19.5 2.8 2 8.6 0.2 3.9 2 1 0 2 2 2 2 EF-hand domain pair WD40_alt PF14077.1 CDJ66729.1 - 0.059 13.0 15.9 2 8.1 0.7 4.0 3 0 0 3 3 3 0 Alternative WD40 repeat motif RRM_1 PF00076.17 CDJ66731.1 - 2.3e-17 62.3 0.0 1.5e-11 43.7 0.0 4.1 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ66731.1 - 2.5e-16 59.3 0.0 2.4e-10 40.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ66731.1 - 3.1e-06 26.9 0.0 1.4e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TrmB PF01978.14 CDJ66731.1 - 0.0086 15.7 0.0 0.22 11.2 0.0 2.6 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.1 CDJ66731.1 - 0.019 15.0 0.0 0.64 10.1 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn helix PRP21_like_P PF12230.3 CDJ66732.1 - 3.4e-44 151.0 16.2 4.8e-44 150.5 5.4 3.0 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CDJ66732.1 - 2.8e-33 113.3 2.2 9.5e-16 57.1 0.0 2.9 3 0 0 3 3 3 2 Surp module DUF1682 PF07946.9 CDJ66732.1 - 0.0012 17.8 2.8 0.0012 17.8 1.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1682) DUF4237 PF14021.1 CDJ66732.1 - 0.11 12.8 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4237) BNIP2 PF12496.3 CDJ66732.1 - 3.6 7.7 8.5 1.4 9.0 1.9 2.4 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Peptidase_S9 PF00326.16 CDJ66733.1 - 8.3e-26 90.5 0.0 5.4e-21 74.7 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CDJ66733.1 - 6e-10 39.3 0.1 2.5e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDJ66733.1 - 5.3e-08 32.7 0.0 2e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ66733.1 - 1.8e-07 30.9 0.1 1.2e-05 24.9 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 CDJ66733.1 - 0.0063 15.7 0.1 0.019 14.2 0.0 1.8 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S28 PF05577.7 CDJ66733.1 - 0.0072 14.9 0.0 0.014 13.9 0.0 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase S28 COesterase PF00135.23 CDJ66733.1 - 0.044 12.4 0.0 0.044 12.4 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family Hid1 PF12722.2 CDJ66733.1 - 1.3 6.6 10.7 1.8 6.1 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PapD-like PF14874.1 CDJ66734.1 - 0.0019 18.1 0.6 1.1 9.2 0.0 4.1 4 0 0 4 4 4 1 Flagellar-associated PapD-like Gemin6 PF06372.7 CDJ66734.1 - 0.014 14.7 0.2 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 Gemin6 protein TPR_11 PF13414.1 CDJ66735.1 - 5.5e-13 48.3 8.6 9.4e-11 41.2 1.2 2.6 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 CDJ66735.1 - 2.4e-11 44.0 14.1 3.2e-07 30.8 3.6 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ66735.1 - 1.2e-10 40.5 4.6 6e-09 35.1 0.3 3.0 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ66735.1 - 1.2e-08 34.2 9.7 3.5e-07 29.6 0.4 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ66735.1 - 4.5e-05 23.7 4.5 0.00051 20.4 0.4 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ66735.1 - 0.00025 20.8 3.0 0.00079 19.2 1.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ66735.1 - 0.00075 19.7 1.3 0.00075 19.7 0.9 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ66735.1 - 0.0017 18.4 1.0 0.25 11.6 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF1641 PF07849.6 CDJ66735.1 - 0.0063 16.1 0.2 0.018 14.6 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1641) TPR_8 PF13181.1 CDJ66735.1 - 0.024 14.4 0.1 0.024 14.4 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ66735.1 - 0.037 13.9 0.8 0.037 13.9 0.6 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CDJ66735.1 - 0.079 13.1 1.2 0.2 11.8 0.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Spc7_N PF15402.1 CDJ66735.1 - 0.93 7.4 8.4 1.5 6.7 5.8 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 BSD PF03909.12 CDJ66736.1 - 7.4e-11 41.6 0.2 1.3e-05 24.8 0.1 2.9 2 0 0 2 2 2 2 BSD domain Mus7 PF09462.5 CDJ66736.1 - 0.042 12.6 0.6 0.084 11.7 0.4 1.4 1 0 0 1 1 1 0 Mus7/MMS22 family DUF4319 PF14203.1 CDJ66736.1 - 0.37 10.3 2.4 2.2 7.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4319) PLDc PF00614.17 CDJ66737.1 - 7.8e-08 31.8 0.0 0.0057 16.4 0.0 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CDJ66737.1 - 1.2e-05 25.0 0.0 0.084 12.6 0.0 2.8 3 0 0 3 3 3 2 PLD-like domain cwf21 PF08312.7 CDJ66739.1 - 1.1e-08 34.8 8.2 1.1e-08 34.8 5.7 3.5 3 1 0 3 3 3 1 cwf21 domain Mcp5_PH PF12814.2 CDJ66740.1 - 0.062 13.2 0.0 9.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology CKS PF01111.14 CDJ66741.1 - 1.3e-05 24.8 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit CTDII PF01556.13 CDJ66742.1 - 5.9e-26 90.1 0.0 1.8e-16 59.7 0.0 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CDJ66742.1 - 6.3e-10 38.9 13.7 1.5e-09 37.7 9.5 1.7 1 1 0 1 1 1 1 DnaJ central domain Lar_restr_allev PF14354.1 CDJ66742.1 - 0.15 12.3 3.0 0.46 10.8 2.0 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar DZR PF12773.2 CDJ66742.1 - 0.32 10.8 17.0 1.2 9.0 3.0 2.6 2 1 1 3 3 3 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 CDJ66742.1 - 5.2 6.8 9.5 1 9.1 1.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) M20_dimer PF07687.9 CDJ66743.1 - 1.6e-08 34.2 0.0 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 CDJ66743.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 CDJ66744.1 - 1.9e-18 65.5 13.4 5.3e-05 22.9 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Peptidase_M20 PF01546.23 CDJ66744.1 - 1.5e-06 27.8 0.0 0.001 18.6 0.0 3.8 4 0 0 4 4 4 1 Peptidase family M20/M25/M40 Nucleoporin_N PF08801.6 CDJ66744.1 - 0.033 12.9 0.1 0.1 11.3 0.0 1.7 1 1 0 1 1 1 0 Nup133 N terminal like Prion PF00377.13 CDJ66747.1 - 0.12 12.0 0.5 0.25 11.0 0.3 1.6 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain DUF2951 PF11166.3 CDJ66748.1 - 0.038 13.8 1.2 0.14 12.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF3381 PF11861.3 CDJ66748.1 - 0.045 13.2 4.2 0.083 12.3 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3560 PF12083.3 CDJ66748.1 - 0.084 12.9 1.9 1 9.4 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Act-Frag_cataly PF09192.5 CDJ66748.1 - 0.088 11.7 1.4 0.59 9.0 0.2 2.1 2 0 0 2 2 2 0 Actin-fragmin kinase, catalytic V-SNARE_C PF12352.3 CDJ66748.1 - 1.3 9.1 9.0 6 7.0 0.0 3.9 4 1 1 5 5 5 0 Snare region anchored in the vesicle membrane C-terminus Tropomyosin_1 PF12718.2 CDJ66748.1 - 1.8 8.4 8.8 0.96 9.2 1.8 2.5 2 0 0 2 2 2 0 Tropomyosin like FlxA PF14282.1 CDJ66748.1 - 3.4 7.6 9.8 0.44 10.5 1.9 2.6 2 1 0 2 2 2 0 FlxA-like protein A_deaminase PF00962.17 CDJ66749.1 - 2.9e-56 190.7 0.0 4.4e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Interfer-bind PF09294.5 CDJ66749.1 - 0.11 12.4 0.1 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III DUF1799 PF08809.6 CDJ66750.1 - 0.003 17.3 0.6 0.0049 16.6 0.3 1.5 1 1 0 1 1 1 1 Phage related hypothetical protein (DUF1799) DUF2397 PF09660.5 CDJ66750.1 - 0.12 10.8 5.8 0.14 10.7 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) CENP-Q PF13094.1 CDJ66750.1 - 0.16 12.0 4.2 0.18 11.7 2.9 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3138 PF11336.3 CDJ66750.1 - 0.23 9.5 6.7 0.26 9.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) HpaP PF09483.5 CDJ66750.1 - 0.67 9.8 8.1 1.2 9.1 5.6 1.5 1 1 0 1 1 1 0 Type III secretion protein (HpaP) Chorion_2 PF03964.10 CDJ66750.1 - 4.4 7.9 7.5 5.9 7.4 4.6 1.6 1 1 1 2 2 2 0 Chorion family 2 TSA PF03249.8 CDJ66750.1 - 6.7 5.1 8.7 6.7 5.1 6.0 1.1 1 0 0 1 1 1 0 Type specific antigen BAF1_ABF1 PF04684.8 CDJ66753.1 - 0.00016 20.7 36.0 0.00018 20.4 24.9 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Spore_coat_CotO PF14153.1 CDJ66753.1 - 0.03 13.7 10.4 0.027 13.8 7.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Fusion_gly PF00523.13 CDJ66753.1 - 0.03 12.3 5.1 0.036 12.1 3.6 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF4175 PF13779.1 CDJ66753.1 - 0.058 11.1 33.6 0.058 11.1 23.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SseB PF07179.7 CDJ66753.1 - 0.15 11.8 2.2 0.2 11.4 1.5 1.1 1 0 0 1 1 1 0 SseB protein N-terminal domain Tim54 PF11711.3 CDJ66753.1 - 0.25 9.8 4.0 0.23 10.0 2.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.4 CDJ66753.1 - 0.27 9.4 27.7 0.25 9.5 19.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chorion_2 PF03964.10 CDJ66753.1 - 0.27 11.7 9.4 0.41 11.2 6.5 1.3 1 0 0 1 1 1 0 Chorion family 2 Plasmodium_Vir PF05795.6 CDJ66753.1 - 0.33 10.1 1.8 0.31 10.1 1.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1387 PF07139.6 CDJ66753.1 - 0.42 10.1 5.0 0.45 10.0 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ctr PF04145.10 CDJ66753.1 - 0.44 10.5 4.2 0.46 10.5 2.9 1.2 1 0 0 1 1 1 0 Ctr copper transporter family BRF1 PF07741.8 CDJ66753.1 - 0.45 10.7 13.1 0.57 10.4 9.1 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF1764 PF08576.5 CDJ66753.1 - 0.49 11.1 12.1 0.57 10.9 8.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Ribosomal_60s PF00428.14 CDJ66753.1 - 0.61 10.5 7.8 1.1 9.7 5.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Slp PF03843.8 CDJ66753.1 - 0.68 8.9 8.0 0.97 8.4 5.5 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family TMEM51 PF15345.1 CDJ66753.1 - 0.92 9.1 12.3 0.97 9.0 8.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 SAGA-Tad1 PF12767.2 CDJ66753.1 - 1.2 8.7 12.5 1.3 8.6 8.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2076 PF09849.4 CDJ66753.1 - 1.8 8.5 25.7 2.3 8.2 17.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM176 PF14851.1 CDJ66753.1 - 2.9 7.5 6.3 3.2 7.4 4.3 1.1 1 0 0 1 1 1 0 FAM176 family Ycf1 PF05758.7 CDJ66753.1 - 3 5.4 9.7 2.8 5.5 6.7 1.0 1 0 0 1 1 1 0 Ycf1 Glyco_transf_15 PF01793.11 CDJ66753.1 - 3.1 6.6 10.2 3.5 6.4 7.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Afi1 PF07792.7 CDJ66753.1 - 3.2 7.7 12.7 3.7 7.5 8.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FLO_LFY PF01698.11 CDJ66753.1 - 3.9 6.2 12.6 4.6 5.9 8.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 CDJ66753.1 - 4 7.1 8.1 4.3 7.0 5.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Gti1_Pac2 PF09729.4 CDJ66753.1 - 4.1 7.2 8.9 4.5 7.1 6.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Suf PF05843.9 CDJ66753.1 - 4.4 6.9 18.1 4.5 6.9 12.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 CDJ66753.1 - 4.6 4.7 13.2 4.7 4.7 9.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDJ66753.1 - 4.6 5.5 11.1 4.7 5.5 7.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3299 PF11736.3 CDJ66753.1 - 4.8 7.0 10.9 6.2 6.7 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) CDC45 PF02724.9 CDJ66753.1 - 4.9 5.0 9.9 4.9 5.0 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.8 CDJ66753.1 - 5.6 6.4 11.6 5.7 6.3 8.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 CDJ66753.1 - 6.5 6.4 10.0 6.8 6.4 6.9 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 CDJ66753.1 - 6.7 6.5 10.8 6.9 6.4 7.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF775 PF05603.7 CDJ66753.1 - 7.4 6.0 14.3 11 5.5 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF966 PF06136.8 CDJ66753.1 - 7.7 5.8 11.8 8.6 5.6 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S49_N PF08496.5 CDJ66753.1 - 8.4 6.1 11.5 10 5.9 8.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3371 PF11851.3 CDJ66753.1 - 8.4 7.0 17.7 12 6.6 12.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) HGTP_anticodon2 PF12745.2 CDJ66753.1 - 9 5.3 10.7 9.2 5.3 7.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF3469 PF11952.3 CDJ66754.1 - 3.1e-07 29.9 1.7 5.2e-07 29.2 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3469) DED PF01335.16 CDJ66754.1 - 0.065 13.3 0.8 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Death effector domain Peptidase_S64 PF08192.6 CDJ66754.1 - 0.22 9.7 2.9 0.25 9.6 2.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 ASF1_hist_chap PF04729.8 CDJ66756.1 - 1.5e-09 37.6 0.1 2.1e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF3357 PF11837.3 CDJ66757.1 - 0.0024 17.7 6.3 0.23 11.3 0.2 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3357) BPD_transp_2 PF02653.11 CDJ66757.1 - 0.0075 15.2 0.9 0.014 14.4 0.6 1.3 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component YajC PF02699.10 CDJ66757.1 - 0.0085 15.7 4.1 0.013 15.1 0.8 2.0 2 0 0 2 2 2 1 Preprotein translocase subunit Sex_peptide PF08138.6 CDJ66757.1 - 0.0093 15.7 0.7 0.97 9.3 0.0 2.4 2 0 0 2 2 2 1 Sex peptide (SP) family MRAP PF15183.1 CDJ66757.1 - 0.068 12.7 1.1 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family PIG-U PF06728.8 CDJ66757.1 - 0.075 11.8 0.8 0.15 10.9 0.6 1.5 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U Baculo_11_kDa PF06143.6 CDJ66757.1 - 0.2 11.0 0.8 3.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family BatD PF13584.1 CDJ66757.1 - 0.49 8.9 1.6 0.79 8.2 0.1 1.8 2 0 0 2 2 2 0 Oxygen tolerance Ribosomal_60s PF00428.14 CDJ66757.1 - 0.73 10.2 15.5 1.3 9.5 10.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Conotoxin PF02950.12 CDJ66757.1 - 1.2 9.9 6.3 4.3 8.2 0.2 2.7 3 0 0 3 3 3 0 Conotoxin CcmH PF03918.9 CDJ66757.1 - 3.5 6.6 9.6 0.33 9.9 0.2 2.8 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Peptidase_M41 PF01434.13 CDJ66758.1 - 5.2e-46 156.7 4.4 1.2e-43 149.0 3.0 2.1 1 1 0 1 1 1 1 Peptidase family M41 SR-25 PF10500.4 CDJ66758.1 - 0.0016 17.9 8.9 0.0028 17.1 6.2 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4653 PF15546.1 CDJ66758.1 - 0.004 16.4 2.2 0.0065 15.7 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) DUF3633 PF12315.3 CDJ66758.1 - 0.065 12.5 2.9 0.18 11.0 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) Peptidase_M50B PF13398.1 CDJ66758.1 - 0.08 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like CAF-1_p150 PF11600.3 CDJ66758.1 - 0.56 9.5 6.7 1 8.6 4.6 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF515 PF04415.7 CDJ66758.1 - 0.58 8.3 6.8 0.78 7.9 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Corona_nucleoca PF00937.13 CDJ66758.1 - 1.9 7.3 5.5 2.8 6.8 3.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DEAD PF00270.24 CDJ66759.1 - 1.1e-42 145.3 0.0 4.4e-41 140.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ66759.1 - 1.3e-26 92.2 0.0 3.5e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDJ66759.1 - 0.00014 21.7 0.0 0.0017 18.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CDJ66759.1 - 0.0022 17.3 0.5 0.0041 16.4 0.3 1.5 1 1 0 1 1 1 1 SecA DEAD-like domain Aldolase PF01081.14 CDJ66759.1 - 0.058 12.5 0.0 0.85 8.7 0.0 2.4 3 0 0 3 3 3 0 KDPG and KHG aldolase PI-PLC-X PF00388.14 CDJ66761.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain zf-CCHC_3 PF13917.1 CDJ66763.1 - 0.018 14.7 0.5 0.054 13.2 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle Galactosyl_T PF01762.16 CDJ66764.1 - 2.9e-44 151.0 0.0 3.6e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CDJ66764.1 - 2.2e-05 23.8 0.0 3.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 CDJ66765.1 - 8.3e-30 103.8 0.0 3.5e-27 95.2 0.0 2.0 2 0 0 2 2 2 2 Galactosyltransferase MMR_HSR1 PF01926.18 CDJ66766.1 - 4.4e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CDJ66766.1 - 0.0012 18.7 3.0 0.035 13.9 0.1 2.6 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 CDJ66766.1 - 0.0062 16.0 0.0 0.76 9.1 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CDJ66766.1 - 0.0063 16.5 2.8 0.18 11.7 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CDJ66766.1 - 0.011 14.9 0.1 0.027 13.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CDJ66766.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RskA PF10099.4 CDJ66766.1 - 0.025 14.3 3.9 0.039 13.7 2.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Med15 PF09606.5 CDJ66766.1 - 0.028 12.6 5.9 0.036 12.2 4.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_IV_A PF09547.5 CDJ66766.1 - 0.036 12.7 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_29 PF13555.1 CDJ66766.1 - 0.059 12.9 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CDJ66766.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase G-alpha PF00503.15 CDJ66766.1 - 0.097 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit HA2 PF04408.18 CDJ66767.1 - 1.2e-25 89.4 0.4 1.6e-24 85.8 0.1 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CDJ66767.1 - 5.4e-21 74.5 0.1 1.7e-20 72.9 0.1 1.9 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CDJ66767.1 - 1.4e-10 40.9 0.4 3.6e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SSP160 PF06933.6 CDJ66767.1 - 0.047 11.6 16.3 0.061 11.2 11.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1173 PF06666.6 CDJ66767.1 - 0.07 11.9 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) TPR_11 PF13414.1 CDJ66768.1 - 8.7e-08 31.7 17.3 5.3e-05 22.7 0.0 5.0 4 1 1 5 5 5 3 TPR repeat TPR_8 PF13181.1 CDJ66768.1 - 9.5e-08 31.2 0.1 0.13 12.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ66768.1 - 2.2e-06 27.8 36.3 0.0066 16.9 1.3 7.3 6 3 2 8 8 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ66768.1 - 2.9e-06 27.5 30.6 0.00026 21.2 0.2 5.2 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ66768.1 - 5.3e-06 25.9 9.7 0.00062 19.4 0.2 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ66768.1 - 7e-06 25.4 2.0 0.0045 16.5 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ66768.1 - 8.7e-05 22.4 6.1 1.4 9.2 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ66768.1 - 0.0065 16.3 0.1 0.0065 16.3 0.0 5.1 3 1 4 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ66768.1 - 0.0075 16.0 21.5 0.038 13.8 0.1 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ66768.1 - 0.017 14.8 0.1 3 7.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ66768.1 - 0.12 12.9 0.2 0.12 12.9 0.2 4.1 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF3366 PF11846.3 CDJ66768.1 - 0.12 12.1 0.0 0.12 12.1 0.0 2.6 3 1 0 3 3 1 0 Domain of unknown function (DUF3366) SR-25 PF10500.4 CDJ66768.1 - 1.3 8.4 24.3 2.8 7.3 11.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cnd1_N PF12922.2 CDJ66768.1 - 4.7 6.8 9.4 1.5 8.4 0.1 3.1 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term TFIIF_alpha PF05793.7 CDJ66768.1 - 5.9 5.1 13.8 7.4 4.8 0.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Parvo_coat PF00740.13 CDJ66769.1 - 7.2 5.4 9.0 11 4.8 6.2 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 MSP1_C PF07462.6 CDJ66770.1 - 0.66 8.2 7.4 0.85 7.9 5.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NIF PF03031.13 CDJ66771.1 - 4.7e-14 52.3 0.0 7.3e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase TFIIA PF03153.8 CDJ66771.1 - 8.4e-05 22.6 24.5 8.4e-05 22.6 17.0 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit HAD_2 PF13419.1 CDJ66771.1 - 0.0025 18.0 1.3 0.3 11.3 0.0 2.9 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF4349 PF14257.1 CDJ66773.1 - 0.095 11.9 3.5 0.12 11.5 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Med3 PF11593.3 CDJ66773.1 - 8.3 5.5 11.5 11 5.1 8.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.4 CDJ66774.1 - 0.013 14.9 10.9 0.013 14.9 7.6 3.2 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.3 CDJ66775.1 - 0.17 10.5 24.6 0.26 10.0 17.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Herpes_glycop PF01528.11 CDJ66775.1 - 0.61 8.7 5.4 1.1 7.8 3.8 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Ycf1 PF05758.7 CDJ66776.1 - 0.23 9.1 27.8 0.26 8.9 19.3 1.1 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 CDJ66776.1 - 0.48 9.2 21.1 0.55 9.0 14.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4175 PF13779.1 CDJ66776.1 - 0.96 7.0 68.9 1.2 6.7 47.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TT_ORF1 PF02956.9 CDJ66776.1 - 1.2 7.4 20.3 1.4 7.3 14.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 PAT1 PF09770.4 CDJ66776.1 - 2.3 6.3 62.7 2.8 6.0 43.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDJ66777.1 - 0.0042 16.4 42.6 0.0047 16.3 29.5 1.1 1 0 0 1 1 1 1 SprA-related family AAA_23 PF13476.1 CDJ66777.1 - 0.01 16.1 14.4 0.011 16.0 10.0 1.3 1 0 0 1 1 1 0 AAA domain POM121 PF15229.1 CDJ66777.1 - 0.24 10.8 28.4 0.33 10.3 19.7 1.2 1 0 0 1 1 1 0 POM121 family FLO_LFY PF01698.11 CDJ66777.1 - 0.29 9.9 21.3 0.32 9.8 14.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Corona_nucleoca PF00937.13 CDJ66777.1 - 0.31 9.9 27.0 0.36 9.7 18.7 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AUX_IAA PF02309.11 CDJ66777.1 - 0.36 10.5 18.3 0.39 10.4 12.7 1.3 1 0 0 1 1 1 0 AUX/IAA family Herpes_UL87 PF03043.9 CDJ66777.1 - 0.57 8.5 11.0 0.54 8.5 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Herpes_DNAp_acc PF04929.7 CDJ66777.1 - 0.57 9.0 23.2 0.62 8.9 16.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SR-25 PF10500.4 CDJ66777.1 - 0.69 9.3 39.2 0.88 9.0 27.1 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rtf2 PF04641.7 CDJ66777.1 - 1.4 8.0 24.6 1.7 7.7 17.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2146 PF10220.4 CDJ66777.1 - 2.3 6.0 23.5 2.6 5.9 16.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) GPCR_chapero_1 PF11904.3 CDJ66777.1 - 2.6 7.1 16.6 2.6 7.0 11.5 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF4045 PF13254.1 CDJ66777.1 - 2.6 7.2 26.7 3 7.0 18.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SID-1_RNA_chan PF13965.1 CDJ66777.1 - 2.6 6.1 9.7 2.6 6.0 6.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GAGA_bind PF06217.7 CDJ66777.1 - 3 7.7 24.7 3.5 7.5 17.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 CDJ66777.1 - 3.1 5.3 20.1 3.3 5.3 13.9 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDJ66777.1 - 4.6 4.7 23.2 4.6 4.7 16.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDJ66777.1 - 5.3 5.4 21.1 5.9 5.3 14.6 1.2 1 0 0 1 1 1 0 Raftlin DUF913 PF06025.7 CDJ66777.1 - 7.1 5.2 14.1 8.1 5.0 9.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.17 CDJ66777.1 - 7.4 5.4 10.6 9 5.2 7.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CDJ66777.1 - 8.4 4.2 29.9 9.6 4.1 20.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 CDJ66778.1 - 5.9e-11 41.8 0.1 2.2e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ66778.1 - 7.4e-06 25.8 0.1 1.7e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ66778.1 - 0.0019 18.0 0.0 0.01 15.6 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_TAC PF06222.6 CDJ66778.1 - 0.0067 15.9 0.2 0.048 13.2 0.1 2.1 1 1 0 1 1 1 1 Phage tail assembly chaperone IncA PF04156.9 CDJ66780.1 - 0.0018 17.8 4.6 0.0024 17.4 3.2 1.1 1 0 0 1 1 1 1 IncA protein DUF218 PF02698.12 CDJ66780.1 - 0.048 13.1 4.4 0.053 13.0 3.0 1.0 1 0 0 1 1 1 0 DUF218 domain Claudin_2 PF13903.1 CDJ66780.1 - 0.088 12.4 6.8 0.1 12.3 4.7 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2776 PF10951.3 CDJ66780.1 - 0.48 9.4 6.6 0.52 9.3 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) RAB3GAP2_N PF14655.1 CDJ66780.1 - 0.55 9.1 5.8 0.53 9.2 4.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 CDJ66780.1 - 5 5.7 7.3 5.4 5.6 5.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) ZYG-11_interact PF05884.7 CDJ66780.1 - 9 5.2 12.7 11 5.0 8.8 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 SNARE_assoc PF09335.6 CDJ66782.1 - 7.4e-09 35.8 0.7 8.8e-08 32.3 0.0 3.0 4 0 0 4 4 4 1 SNARE associated Golgi protein SAGA-Tad1 PF12767.2 CDJ66782.1 - 5e-06 26.3 12.1 5e-06 26.3 8.4 3.0 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit Herpes_UL87 PF03043.9 CDJ66782.1 - 0.0012 17.3 0.1 0.0019 16.7 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL87 family Ctr PF04145.10 CDJ66782.1 - 0.0062 16.5 0.2 0.0062 16.5 0.1 4.4 3 1 0 3 3 3 1 Ctr copper transporter family Presenilin PF01080.12 CDJ66782.1 - 0.0064 15.3 5.0 0.009 14.8 2.5 2.0 2 0 0 2 2 2 1 Presenilin Plasmodium_Vir PF05795.6 CDJ66782.1 - 0.05 12.8 0.0 0.17 11.0 0.0 1.9 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF4149 PF13664.1 CDJ66782.1 - 0.89 9.6 9.8 11 6.1 3.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) CDC45 PF02724.9 CDJ66782.1 - 1 7.3 19.5 0.14 10.1 10.4 1.7 2 0 0 2 2 2 0 CDC45-like protein Tim54 PF11711.3 CDJ66782.1 - 1.4 7.3 14.4 2.4 6.6 10.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 CDJ66782.1 - 2.7 5.5 20.4 0.029 12.0 8.8 1.5 2 0 0 2 2 2 0 Ycf1 PBP1_TM PF14812.1 CDJ66783.1 - 0.2 11.9 5.9 2 8.7 0.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 CDJ66783.1 - 0.24 10.1 13.9 0.47 9.1 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PAT1 PF09770.4 CDJ66783.1 - 1.2 7.2 57.4 1.6 6.8 39.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med3 PF11593.3 CDJ66784.1 - 1.1e-06 28.2 27.2 1.1e-06 28.2 18.8 2.2 1 1 1 2 2 2 1 Mediator complex subunit 3 fungal Baculo_PEP_C PF04513.7 CDJ66784.1 - 3.4e-05 23.7 17.8 9.1e-05 22.3 12.4 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 CDJ66784.1 - 4.7 7.0 9.2 4.4 7.1 4.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SR-25 PF10500.4 CDJ66785.1 - 0.00019 21.0 26.4 0.0025 17.3 8.2 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein NAM-associated PF14303.1 CDJ66785.1 - 0.00089 19.5 15.1 0.0013 19.0 10.5 1.3 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain SID-1_RNA_chan PF13965.1 CDJ66785.1 - 0.0037 15.5 6.1 0.0045 15.2 4.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 RIC3 PF15361.1 CDJ66785.1 - 0.0052 17.0 4.1 0.0052 17.0 2.8 2.1 2 0 0 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 SOBP PF15279.1 CDJ66785.1 - 0.0077 16.6 15.9 0.0098 16.3 11.0 1.0 1 0 0 1 1 1 1 Sine oculis-binding protein PBP1_TM PF14812.1 CDJ66785.1 - 0.0097 16.1 7.8 0.63 10.3 0.0 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.11 CDJ66785.1 - 0.44 9.5 5.0 0.16 10.8 1.9 1.5 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit KASH PF10541.4 CDJ66785.1 - 0.54 10.1 7.3 0.4 10.5 2.1 2.1 2 0 0 2 2 2 0 Nuclear envelope localisation domain FAM176 PF14851.1 CDJ66785.1 - 0.66 9.6 9.6 0.12 12.0 0.4 2.2 2 0 0 2 2 2 0 FAM176 family Herpes_DNAp_acc PF04929.7 CDJ66785.1 - 1.9 7.4 19.3 2.7 6.8 3.5 2.0 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DUF1510 PF07423.6 CDJ66785.1 - 2.5 7.4 23.8 0.024 14.0 7.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Activator_LAG-3 PF11498.3 CDJ66785.1 - 2.6 6.6 66.2 3.1 6.4 45.9 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FLO_LFY PF01698.11 CDJ66785.1 - 4.6 5.9 17.7 1.2 7.8 5.5 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF4512 PF14975.1 CDJ66785.1 - 4.7 8.1 10.6 1.1 10.1 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DUF3449 PF11931.3 CDJ66785.1 - 5.5 6.4 16.8 0.88 9.0 5.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) CPSF100_C PF13299.1 CDJ66785.1 - 5.5 7.1 16.6 3.4 7.8 4.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal YqfQ PF14181.1 CDJ66785.1 - 5.9 6.9 24.6 1.4 8.9 7.5 2.2 2 0 0 2 2 2 0 YqfQ-like protein BNIP3 PF06553.7 CDJ66785.1 - 7 5.9 27.3 2.5 7.4 6.8 2.1 2 0 0 2 2 2 0 BNIP3 FNIP_N PF14636.1 CDJ66785.1 - 8.6 6.8 23.4 6.1 7.3 3.4 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Syja_N PF02383.13 CDJ66786.1 - 2.8e-24 85.4 23.0 1.4e-21 76.5 0.0 5.1 4 1 1 5 5 5 3 SacI homology domain Exo_endo_phos PF03372.18 CDJ66786.1 - 1.4e-06 28.4 0.0 3.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OmpH PF03938.9 CDJ66786.1 - 6.9e-06 26.0 30.1 6.9e-06 26.0 20.9 8.5 6 2 0 6 6 6 1 Outer membrane protein (OmpH-like) FBPase PF00316.15 CDJ66787.1 - 9.4e-20 70.6 0.0 1.3e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase SR-25 PF10500.4 CDJ66787.1 - 2.5 7.5 14.9 4.6 6.6 10.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2763 PF10961.3 CDJ66787.1 - 6.8 7.1 11.0 4.8 7.6 6.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) HK97-gp10_like PF04883.7 CDJ66788.1 - 7.7 7.5 6.6 1.8 9.5 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Asp_protease_2 PF13650.1 CDJ66789.1 - 1.5e-09 38.1 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ66789.1 - 4.4e-06 26.4 0.0 9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ66789.1 - 6.1e-05 22.9 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CDJ66789.1 - 7.3e-05 22.6 0.0 0.00024 20.9 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ66789.1 - 0.0025 17.3 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 CDJ66789.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase zf-CCHC PF00098.18 CDJ66790.1 - 6.2e-07 29.0 2.4 6.2e-07 29.0 1.7 2.5 2 0 0 2 2 2 1 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ66790.1 - 0.0066 16.4 8.5 0.015 15.3 5.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Retrotrans_gag PF03732.12 CDJ66790.1 - 0.0098 15.9 0.0 0.057 13.4 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 CDJ66790.1 - 0.05 13.2 0.6 0.11 12.1 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ66790.1 - 0.36 10.6 7.3 0.22 11.2 0.8 2.6 1 1 1 2 2 2 0 Zinc knuckle BTB_2 PF02214.17 CDJ66791.1 - 7.1e-16 58.2 0.5 5.6e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain UPF0240 PF06784.6 CDJ66791.1 - 0.01 15.5 8.8 0.013 15.1 6.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Vfa1 PF08432.5 CDJ66791.1 - 0.024 14.6 13.5 0.027 14.4 9.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Endonuc-BglII PF09195.6 CDJ66791.1 - 0.069 12.6 2.7 0.086 12.3 1.8 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglII C1q PF00386.16 CDJ66791.1 - 0.17 11.9 1.9 0.18 11.7 0.5 1.7 1 1 0 1 1 1 0 C1q domain Erp_C PF06780.6 CDJ66791.1 - 0.29 10.9 7.5 0.37 10.6 4.8 1.5 1 1 0 1 1 1 0 Erp protein C-terminus HlyD_2 PF12700.2 CDJ66791.1 - 0.33 10.0 6.4 0.39 9.8 4.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein APG6 PF04111.7 CDJ66791.1 - 0.4 9.6 21.0 0.53 9.2 14.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CDJ66791.1 - 3.1 6.1 10.1 3.5 5.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CDJ66791.1 - 3.1 5.5 8.5 3.4 5.3 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med15 PF09606.5 CDJ66791.1 - 3.4 5.7 14.6 3.8 5.5 10.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3373 PF11853.3 CDJ66791.1 - 3.5 6.0 5.9 4.1 5.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DRY_EERY PF09750.4 CDJ66791.1 - 3.7 7.6 10.7 1.9 8.5 6.0 1.5 1 1 1 2 2 2 0 Alternative splicing regulator Mnd1 PF03962.10 CDJ66791.1 - 4.4 6.9 19.7 6.1 6.4 13.7 1.2 1 0 0 1 1 1 0 Mnd1 family Peptidase_C37 PF05416.7 CDJ66791.1 - 5.1 5.2 9.0 5.6 5.1 6.2 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase MCM PF00493.18 CDJ66792.1 - 1.9e-51 174.8 0.1 2.5e-51 174.4 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 CDJ66792.1 - 1.9e-05 24.4 0.0 4.7e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Ribosomal_60s PF00428.14 CDJ66792.1 - 0.011 16.0 4.4 0.011 16.0 3.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Shadoo PF14999.1 CDJ66792.1 - 0.044 13.6 9.8 0.12 12.2 1.0 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Dpy-30 PF05186.8 CDJ66793.1 - 2.1e-05 23.9 0.0 5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif Astro_capsid PF03115.9 CDJ66793.1 - 0.031 12.5 4.8 0.06 11.6 3.4 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor FIBP PF05427.6 CDJ66794.1 - 0.00022 20.6 0.5 0.00027 20.3 0.3 1.3 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) NPH3 PF03000.9 CDJ66794.1 - 0.015 14.8 0.5 0.023 14.1 0.1 1.4 2 0 0 2 2 2 0 NPH3 family RE_Alw26IDE PF09665.5 CDJ66794.1 - 0.034 12.8 2.1 0.034 12.8 0.6 1.5 1 1 1 2 2 2 0 Type II restriction endonuclease (RE_Alw26IDE) Pox_A3L PF05288.6 CDJ66794.1 - 0.095 12.4 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A3L Protein Synuclein PF01387.12 CDJ66795.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Synuclein Trypsin_2 PF13365.1 CDJ66796.1 - 1.4e-15 57.3 0.0 2.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 CDJ66796.1 - 3.4e-07 30.3 0.0 7.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CDJ66796.1 - 7e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_S29 PF02907.10 CDJ66796.1 - 0.004 16.7 0.2 0.0094 15.4 0.2 1.6 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.1 CDJ66796.1 - 0.015 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF3601 PF12208.3 CDJ66796.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) Apc15p PF05841.6 CDJ66798.1 - 0.022 15.4 6.7 0.034 14.8 4.7 1.4 1 0 0 1 1 1 0 Apc15p protein PmbA_TldD PF01523.11 CDJ66798.1 - 0.023 13.9 0.2 0.028 13.7 0.1 1.0 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Pex14_N PF04695.8 CDJ66798.1 - 0.054 13.5 8.5 0.088 12.8 5.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nitroreductase PF00881.19 CDJ66798.1 - 0.058 13.2 5.6 0.073 12.8 3.9 1.2 1 0 0 1 1 1 0 Nitroreductase family DUF966 PF06136.8 CDJ66798.1 - 0.076 12.4 5.3 0.081 12.3 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Med15 PF09606.5 CDJ66798.1 - 0.097 10.8 30.8 0.11 10.6 21.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDK2AP PF09806.4 CDJ66798.1 - 0.11 12.6 22.8 0.071 13.3 14.8 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Neur_chan_memb PF02932.11 CDJ66798.1 - 0.33 10.8 4.7 0.34 10.7 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YfhO PF09586.5 CDJ66798.1 - 0.39 8.6 1.6 0.43 8.5 1.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO tRNA_synt_1c_R2 PF04557.10 CDJ66798.1 - 0.56 10.9 8.3 3.1 8.5 0.2 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 PAT1 PF09770.4 CDJ66798.1 - 0.66 8.1 23.3 0.77 7.9 16.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 CDJ66798.1 - 0.68 9.3 6.1 0.75 9.2 4.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TFIIA PF03153.8 CDJ66798.1 - 1.4 8.7 18.2 1.8 8.3 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex16 PF08610.5 CDJ66798.1 - 1.5 7.7 6.7 1.7 7.5 4.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ribosomal_60s PF00428.14 CDJ66798.1 - 1.7 9.1 17.7 0.086 13.2 8.6 1.6 2 0 0 2 2 1 0 60s Acidic ribosomal protein Macoilin PF09726.4 CDJ66798.1 - 1.9 6.6 18.1 2.4 6.3 12.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Gag_spuma PF03276.9 CDJ66798.1 - 1.9 6.6 15.4 2.2 6.5 10.7 1.2 1 0 0 1 1 1 0 Spumavirus gag protein HGTP_anticodon2 PF12745.2 CDJ66798.1 - 2.2 7.3 7.5 2.8 6.9 5.2 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4175 PF13779.1 CDJ66798.1 - 4.4 4.8 30.3 5.8 4.4 21.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peripla_BP_2 PF01497.13 CDJ66798.1 - 4.9 6.1 8.1 6.6 5.7 5.6 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Hid1 PF12722.2 CDJ66798.1 - 6 4.4 7.2 6.6 4.2 5.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein dCMP_cyt_deam_1 PF00383.17 CDJ66798.1 - 6.2 6.5 7.1 8.1 6.1 4.9 1.4 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF940 PF06082.6 CDJ66798.1 - 6.4 5.2 10.4 7 5.0 7.2 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DUF1906 PF08924.6 CDJ66798.1 - 9.5 6.0 13.1 15 5.4 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) NAD_synthase PF02540.12 CDJ66799.1 - 1.3e-27 96.2 0.0 3.4e-16 58.8 0.0 3.1 3 0 0 3 3 3 3 NAD synthase tRNA_Me_trans PF03054.11 CDJ66799.1 - 0.0048 15.4 0.0 0.029 12.9 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.15 CDJ66799.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Methyltransf_16 PF10294.4 CDJ66799.1 - 0.21 11.0 0.1 0.55 9.6 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Ribosomal_60s PF00428.14 CDJ66799.1 - 3.1 8.2 6.9 0.47 10.8 0.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein TAN PF11640.3 CDJ66800.1 - 0.00027 20.7 0.9 0.00034 20.3 0.6 1.1 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair DUF3446 PF11928.3 CDJ66800.1 - 0.00099 19.2 4.9 0.0017 18.5 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) Mu-like_Pro PF10123.4 CDJ66800.1 - 0.039 13.4 0.6 0.048 13.1 0.4 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein E1-N PF14463.1 CDJ66800.1 - 0.087 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 E1 N-terminal domain TraG-D_C PF12696.2 CDJ66800.1 - 0.33 10.8 2.8 0.42 10.4 1.9 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG SprA-related PF12118.3 CDJ66800.1 - 4.4 6.5 11.4 5.8 6.1 2.8 2.0 2 0 0 2 2 2 0 SprA-related family Pap_E4 PF02711.9 CDJ66800.1 - 9.9 7.0 7.1 34 5.3 0.1 2.1 2 0 0 2 2 2 0 E4 protein HA2 PF04408.18 CDJ66801.1 - 8.1e-19 67.5 0.0 1.5e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CDJ66801.1 - 1.4e-13 50.4 0.0 3.9e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CDJ66801.1 - 0.027 14.3 0.1 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold CobT PF06213.7 CDJ66802.1 - 0.0043 16.2 7.1 0.0043 16.2 5.0 5.1 3 1 2 5 5 5 1 Cobalamin biosynthesis protein CobT Ribosomal_60s PF00428.14 CDJ66802.1 - 0.0045 17.3 12.9 0.0045 17.3 9.0 10.7 8 3 1 9 9 9 1 60s Acidic ribosomal protein Ubiq_cyt_C_chap PF03981.7 CDJ66804.1 - 3.6e-12 46.3 1.3 2.4e-05 24.1 0.0 3.2 3 0 0 3 3 3 2 Ubiquinol-cytochrome C chaperone SR-25 PF10500.4 CDJ66804.1 - 9 5.6 15.5 16 4.9 10.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDJ66805.1 - 0.076 11.2 50.2 0.099 10.8 34.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDJ66805.1 - 0.19 12.0 8.9 0.31 11.3 6.2 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Phosducin PF02114.11 CDJ66805.1 - 0.32 9.6 0.0 0.32 9.6 0.0 3.5 3 1 1 4 4 4 0 Phosducin DUF4638 PF15472.1 CDJ66805.1 - 1.2 8.6 13.2 2.7 7.4 9.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4638) G-7-MTase PF12803.2 CDJ66805.1 - 1.2 8.2 7.7 1.8 7.6 5.3 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Hid1 PF12722.2 CDJ66805.1 - 2.1 5.9 10.4 2.1 5.8 7.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF572 PF04502.8 CDJ66805.1 - 3.8 6.6 24.3 1.8 7.7 14.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.5 CDJ66805.1 - 5.9 5.1 9.1 6.4 5.0 6.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.14 CDJ66805.1 - 9.5 3.9 8.6 9.9 3.8 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MSP1_C PF07462.6 CDJ66806.1 - 0.16 10.3 5.1 0.17 10.2 3.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Wzz PF02706.10 CDJ66806.1 - 0.36 10.6 2.7 0.47 10.2 1.9 1.3 1 0 0 1 1 1 0 Chain length determinant protein DUF533 PF04391.7 CDJ66807.1 - 0.01 15.2 1.8 0.012 15.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Activator_LAG-3 PF11498.3 CDJ66807.1 - 0.024 13.3 9.5 0.023 13.4 6.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.3 CDJ66807.1 - 0.058 12.7 1.0 0.059 12.7 0.7 1.1 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDJ66807.1 - 0.16 11.0 3.7 0.16 11.0 2.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein BaxI_1 PF12811.2 CDJ66807.1 - 0.26 10.4 1.8 0.27 10.3 1.3 1.0 1 0 0 1 1 1 0 Bax inhibitor 1 like BAF1_ABF1 PF04684.8 CDJ66807.1 - 0.27 10.0 5.0 0.27 10.0 3.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Androgen_recep PF02166.11 CDJ66807.1 - 0.78 8.5 7.7 0.86 8.3 5.4 1.1 1 0 0 1 1 1 0 Androgen receptor PHD_3 PF13922.1 CDJ66807.1 - 6.1 7.1 7.5 3 8.1 3.9 1.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Med3 PF11593.3 CDJ66807.1 - 6.9 5.7 11.4 7.9 5.5 7.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.4 CDJ66808.1 - 0.0025 17.3 6.3 0.0025 17.3 4.3 7.7 5 1 2 7 7 7 2 Nuclear RNA-splicing-associated protein Abhydrolase_3 PF07859.8 CDJ66809.1 - 1.6e-33 116.0 0.0 1.6e-33 116.0 0.0 3.6 3 3 1 4 4 4 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDJ66809.1 - 2.3e-11 42.9 0.0 2.3e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) GYF PF02213.11 CDJ66810.1 - 9.4e-10 37.9 0.1 1.7e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 GYF domain HTH_28 PF13518.1 CDJ66811.1 - 0.013 15.4 0.1 0.013 15.4 0.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF746 PF05344.6 CDJ66811.1 - 0.013 14.9 0.2 0.033 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_23 PF13384.1 CDJ66811.1 - 0.03 13.9 0.1 0.03 13.9 0.1 2.5 3 0 0 3 3 3 0 Homeodomain-like domain PhoH PF02562.11 CDJ66811.1 - 0.24 10.5 1.2 0.37 9.9 0.8 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF4138 PF13595.1 CDJ66812.1 - 0.034 13.1 0.4 0.036 13.0 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) DUF1202 PF06717.6 CDJ66812.1 - 0.046 12.9 1.1 0.052 12.8 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DUF2368 PF10166.4 CDJ66812.1 - 0.058 12.9 7.4 0.07 12.7 5.2 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Activator_LAG-3 PF11498.3 CDJ66812.1 - 0.49 9.0 13.8 0.48 9.1 9.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DOR PF14839.1 CDJ66812.1 - 2.5 7.8 6.8 2.5 7.7 4.7 1.0 1 0 0 1 1 1 0 DOR family PHD_3 PF13922.1 CDJ66812.1 - 2.6 8.3 6.2 3.5 7.9 4.3 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Kei1 PF08552.6 CDJ66812.1 - 8.1 6.0 7.1 9.2 5.8 4.9 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RVT_1 PF00078.22 CDJ66814.1 - 1.7e-17 63.5 0.0 3.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CDJ66814.1 - 3.3e-08 33.9 0.0 6.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ66814.1 - 4.6e-08 32.7 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ66814.1 - 4.8e-05 23.2 0.0 0.00015 21.5 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ66814.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3552 PF12072.3 CDJ66814.1 - 0.0091 15.2 0.2 0.014 14.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Asp_protease PF09668.5 CDJ66814.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.12 CDJ66815.1 - 4e-07 30.0 0.1 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDJ66815.1 - 7.6e-06 25.6 14.9 6.5e-05 22.6 1.6 2.8 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ66815.1 - 0.11 12.2 5.7 0.69 9.6 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ66815.1 - 0.26 11.0 7.2 0.11 12.2 0.5 2.5 1 1 1 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ66815.1 - 0.35 10.9 11.0 0.82 9.7 7.6 1.6 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_6 PF15288.1 CDJ66815.1 - 1.4 8.6 9.3 0.21 11.3 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle DEAD PF00270.24 CDJ66818.1 - 6.1e-38 129.9 0.0 7.3e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDJ66818.1 - 0.00063 19.6 0.0 0.0025 17.6 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CDJ66818.1 - 0.0032 16.3 0.0 0.0041 15.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_24 PF13479.1 CDJ66818.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L3 PF00297.17 CDJ66819.1 - 7e-107 356.6 3.8 8.5e-107 356.4 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 RNA_pol_Rpb2_1 PF04563.10 CDJ66821.1 - 8.1e-26 90.1 0.0 1.2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CDJ66821.1 - 1e-22 79.6 0.0 2.3e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CDJ66821.1 - 0.13 11.6 0.0 0.36 10.2 0.0 1.8 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_6 PF00562.23 CDJ66822.1 - 5.5e-117 390.7 0.0 6.6e-117 390.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 CDJ66822.1 - 8e-14 51.6 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Rad50_zn_hook PF04423.9 CDJ66822.1 - 0.0078 15.6 0.2 0.015 14.7 0.2 1.4 1 0 0 1 1 1 1 Rad50 zinc hook motif Lactamase_B_2 PF12706.2 CDJ66825.1 - 8e-14 51.6 0.0 3.8e-12 46.1 0.0 2.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDJ66825.1 - 7.8e-07 28.9 0.4 0.00055 19.6 0.1 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily RRM_1 PF00076.17 CDJ66826.1 - 7.5e-08 31.8 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ66826.1 - 1.6e-07 31.2 0.0 5.8e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ66826.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2182 PF09948.4 CDJ66829.1 - 0.091 12.6 0.8 0.14 12.0 0.6 1.3 1 0 0 1 1 1 0 Predicted metal-binding integral membrane protein (DUF2182) Arteri_nucleo PF01481.11 CDJ66829.1 - 3.1 7.8 9.0 0.24 11.5 2.3 1.9 2 1 0 2 2 2 0 Arterivirus nucleocapsid protein DUF591 PF04569.9 CDJ66829.1 - 7.3 6.7 12.8 15 5.6 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function Mcm10 PF09332.6 CDJ66830.1 - 0.0091 15.3 5.1 0.0091 15.3 3.6 3.0 3 0 0 3 3 3 1 Mcm10 replication factor CDK2AP PF09806.4 CDJ66830.1 - 0.019 15.2 5.4 0.019 15.2 3.7 4.3 4 0 0 4 4 4 0 Cyclin-dependent kinase 2-associated protein TAF4 PF05236.9 CDJ66830.1 - 0.19 10.9 13.7 0.35 10.0 4.3 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Secretin_N_2 PF07655.8 CDJ66830.1 - 0.27 11.6 12.2 0.074 13.4 5.9 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_C14 PF00656.17 CDJ66832.1 - 2.2e-12 47.2 0.0 3.8e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Med15 PF09606.5 CDJ66832.1 - 0.034 12.3 11.9 0.035 12.3 8.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDK2AP PF09806.4 CDJ66832.1 - 0.11 12.7 3.5 0.14 12.3 2.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF755 PF05501.6 CDJ66832.1 - 0.12 12.4 8.4 0.17 11.9 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4106 PF13388.1 CDJ66832.1 - 0.22 10.4 4.0 0.27 10.1 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Conotoxin PF02950.12 CDJ66832.1 - 1.2 9.9 5.2 1.9 9.3 3.6 1.2 1 0 0 1 1 1 0 Conotoxin ERF PF04404.7 CDJ66832.1 - 1.3 8.5 7.4 1.8 8.0 5.1 1.1 1 0 0 1 1 1 0 ERF superfamily DUF4175 PF13779.1 CDJ66832.1 - 1.9 6.0 12.7 2.1 5.9 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) P12 PF12669.2 CDJ66832.1 - 4.3 7.6 8.3 6.2 7.1 5.7 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family BAF1_ABF1 PF04684.8 CDJ66832.1 - 6.1 5.5 12.0 7.1 5.3 8.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 CDJ66835.1 - 0.0058 16.1 10.3 0.0058 16.1 7.2 6.3 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein Zip PF02535.17 CDJ66835.1 - 0.23 10.4 0.0 0.23 10.4 0.0 2.3 3 0 0 3 3 3 0 ZIP Zinc transporter hDGE_amylase PF14701.1 CDJ66835.1 - 1.2 7.9 4.3 14 4.4 0.1 3.3 3 0 0 3 3 3 0 glucanotransferase domain of human glycogen debranching enzyme Prefoldin_2 PF01920.15 CDJ66836.1 - 9.2e-10 38.2 0.1 9.2e-10 38.2 0.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF755 PF05501.6 CDJ66836.1 - 0.00031 20.7 21.5 0.00031 20.7 14.9 1.6 2 0 0 2 2 1 1 Domain of unknown function (DUF755) Dehydrin PF00257.14 CDJ66836.1 - 0.00037 20.8 2.4 0.00037 20.8 1.7 1.2 1 0 0 1 1 1 1 Dehydrin Cwf_Cwc_15 PF04889.7 CDJ66836.1 - 0.0094 15.6 9.1 0.011 15.4 6.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein UPF0560 PF10577.4 CDJ66836.1 - 0.014 13.6 13.8 0.016 13.5 9.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Shadoo PF14999.1 CDJ66836.1 - 0.017 14.9 3.1 0.023 14.5 2.1 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective GPCR_chapero_1 PF11904.3 CDJ66836.1 - 0.06 12.4 4.5 0.062 12.4 3.1 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF2217 PF10265.4 CDJ66836.1 - 0.083 11.6 6.3 0.088 11.5 4.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Plasmodium_Vir PF05795.6 CDJ66836.1 - 0.13 11.4 4.5 0.11 11.6 3.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CD20 PF04103.10 CDJ66836.1 - 0.13 12.1 2.7 0.15 11.9 1.9 1.1 1 0 0 1 1 1 0 CD20-like family Zip PF02535.17 CDJ66836.1 - 0.17 10.8 2.8 0.16 10.9 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Gag_spuma PF03276.9 CDJ66836.1 - 0.2 9.9 9.6 0.2 9.9 6.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Herpes_UL45 PF05473.7 CDJ66836.1 - 0.2 11.0 4.0 0.25 10.7 2.8 1.3 1 0 0 1 1 1 0 UL45 protein Lin-8 PF03353.10 CDJ66836.1 - 0.34 10.1 10.4 0.36 10.0 7.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PepSY_2 PF13670.1 CDJ66836.1 - 0.63 9.9 12.4 1.3 9.0 8.6 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF3824 PF12868.2 CDJ66836.1 - 0.73 10.7 11.9 0.98 10.3 8.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Serinc PF03348.10 CDJ66836.1 - 0.92 8.1 6.8 0.98 8.0 4.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Macoilin PF09726.4 CDJ66836.1 - 0.94 7.6 13.9 0.92 7.7 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Band_3_cyto PF07565.8 CDJ66836.1 - 1 8.8 8.0 1.1 8.7 5.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2229 PF09989.4 CDJ66836.1 - 1.4 8.3 4.1 1.6 8.1 2.8 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Ribosomal_60s PF00428.14 CDJ66836.1 - 1.5 9.2 22.4 2.9 8.3 15.5 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein MelC1 PF06236.6 CDJ66836.1 - 1.5 8.7 10.1 3 7.8 7.0 1.5 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 FimP PF09766.4 CDJ66836.1 - 1.6 7.7 12.1 0.46 9.4 6.6 1.4 2 0 0 2 2 2 0 Fms-interacting protein DUF2782 PF11191.3 CDJ66836.1 - 1.6 8.7 6.0 3.3 7.7 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) DUF4259 PF14078.1 CDJ66836.1 - 1.7 9.1 7.6 2.1 8.8 5.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) SR-25 PF10500.4 CDJ66836.1 - 2.4 7.5 31.2 2.6 7.4 21.1 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Trp_oprn_chp PF09534.5 CDJ66836.1 - 2.6 7.6 13.5 5.3 6.6 9.3 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TFIIA PF03153.8 CDJ66836.1 - 3.2 7.5 21.3 3.6 7.3 14.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Conotoxin PF02950.12 CDJ66836.1 - 4.7 8.0 5.8 9.4 7.1 4.0 1.6 1 0 0 1 1 1 0 Conotoxin RskA PF10099.4 CDJ66836.1 - 5.9 6.5 17.7 13 5.4 12.3 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Ctr PF04145.10 CDJ66836.1 - 8.2 6.4 7.6 9.4 6.2 5.0 1.4 1 1 0 1 1 1 0 Ctr copper transporter family DUF1620 PF07774.8 CDJ66837.1 - 1.4e-22 80.0 0.0 1.3e-17 63.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CDJ66837.1 - 7.1e-07 28.9 19.8 0.00044 19.7 6.6 3.4 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 CDJ66837.1 - 4.8e-05 22.6 0.0 4.4 7.0 0.0 4.5 4 0 0 4 4 4 1 PQQ enzyme repeat Collagen PF01391.13 CDJ66837.1 - 0.0087 15.5 45.7 0.027 13.9 15.7 2.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Peroxin-22 PF12827.2 CDJ66837.1 - 0.035 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family DOPA_dioxygen PF08883.6 CDJ66837.1 - 1.2 9.2 4.8 0.29 11.2 0.3 2.2 2 0 0 2 2 2 0 Dopa 4,5-dioxygenase family ABC2_membrane PF01061.19 CDJ66838.1 - 1.9e-17 63.1 25.4 4.8e-14 52.0 13.3 2.6 1 1 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 CDJ66838.1 - 0.00027 21.2 0.0 0.00027 21.2 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 CDJ66838.1 - 0.015 14.8 0.1 0.064 12.7 0.1 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain MYEOV2 PF15004.1 CDJ66839.1 - 0.096 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Myeloma-overexpressed-like Shisa PF13908.1 CDJ66840.1 - 0.00094 19.4 7.8 0.00094 19.4 5.4 2.7 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator Gastrin PF00918.12 CDJ66840.1 - 0.0057 17.4 4.8 0.0057 17.4 3.3 2.7 2 1 0 2 2 2 1 Gastrin/cholecystokinin family IncA PF04156.9 CDJ66840.1 - 0.013 15.0 10.0 0.027 14.0 6.9 1.4 1 0 0 1 1 1 0 IncA protein DUF3573 PF12097.3 CDJ66840.1 - 0.021 13.4 1.0 0.028 13.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Folate_carrier PF01770.13 CDJ66840.1 - 0.038 12.5 0.5 0.06 11.8 0.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier LCD1 PF09798.4 CDJ66840.1 - 6.6 4.5 11.9 8.6 4.2 8.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein EF-hand_1 PF00036.27 CDJ66843.1 - 4.3e-05 22.5 0.2 0.01 15.0 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CDJ66843.1 - 0.0005 19.7 0.4 0.042 13.7 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 CDJ66843.1 - 0.00071 19.6 0.1 0.058 13.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair Cwf_Cwc_15 PF04889.7 CDJ66843.1 - 0.0036 17.0 19.1 0.0036 17.0 13.3 3.9 2 1 1 3 3 3 1 Cwf15/Cwc15 cell cycle control protein EF-hand_5 PF13202.1 CDJ66843.1 - 0.017 14.4 1.8 0.062 12.6 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CDJ66843.1 - 0.022 14.3 0.2 8.4 6.1 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain pair CTDII PF01556.13 CDJ66844.1 - 3.1e-29 100.7 2.7 3.9e-24 84.3 0.4 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 CDJ66844.1 - 2.5e-20 71.9 3.9 4.8e-20 71.0 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain Plasmid_stabil PF05016.9 CDJ66844.1 - 0.14 12.5 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Plasmid stabilisation system protein UAA PF08449.6 CDJ66845.1 - 1.1e-06 27.8 4.0 2e-06 26.9 2.8 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CDJ66845.1 - 3.5e-06 27.0 3.5 3.5e-06 27.0 2.4 3.5 3 2 1 4 4 4 1 EamA-like transporter family TPT PF03151.11 CDJ66845.1 - 6.9e-06 25.7 12.8 0.053 13.1 0.1 3.5 3 0 0 3 3 3 3 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CDJ66845.1 - 0.00097 18.3 6.9 0.00097 18.3 4.8 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 CDJ66845.1 - 0.02 15.0 3.9 0.02 15.0 2.7 3.8 3 2 0 3 3 3 0 Multidrug resistance efflux transporter DUF1129 PF06570.6 CDJ66845.1 - 2.7 7.2 7.4 5.2 6.3 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) AP2 PF00847.15 CDJ66846.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 AP2 domain Porphobil_deamC PF03900.10 CDJ66846.1 - 0.016 15.2 0.4 0.04 14.0 0.0 1.8 2 0 0 2 2 2 0 Porphobilinogen deaminase, C-terminal domain DUF4267 PF14087.1 CDJ66846.1 - 0.13 11.8 0.1 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) PAP_assoc PF03828.14 CDJ66849.1 - 2.1e-09 37.1 0.0 5.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CDJ66849.1 - 7.3e-05 23.0 0.0 0.00036 20.7 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Patched PF02460.13 CDJ66850.1 - 5.2e-106 355.4 4.6 7.4e-56 189.5 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CDJ66850.1 - 4.6e-33 113.8 8.0 4.6e-33 113.8 5.6 2.7 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation DUF2000 PF09391.5 CDJ66853.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) CRAL_TRIO_2 PF13716.1 CDJ66854.1 - 0.002 18.0 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CDJ66854.1 - 0.017 14.6 0.0 0.058 12.8 0.0 1.9 1 1 0 1 1 1 0 CRAL/TRIO domain Lactamase_B PF00753.22 CDJ66855.1 - 2e-24 86.3 0.5 2.5e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CDJ66855.1 - 0.018 14.6 0.1 0.033 13.7 0.1 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain UPF0139 PF03669.8 CDJ66856.1 - 5.7e-05 22.5 0.1 7.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Mito_carr PF00153.22 CDJ66858.1 - 3.8e-37 125.8 0.1 2.9e-18 65.3 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein N_methyl_2 PF13544.1 CDJ66858.1 - 0.27 10.7 1.3 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Type IV pilin N-term methylation site GFxxxE Mito_carr PF00153.22 CDJ66859.1 - 1.2e-18 66.5 0.0 1.3e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein zf-CCCH PF00642.19 CDJ66862.1 - 9.4e-10 37.9 16.9 0.00012 21.6 0.5 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 CDJ66862.1 - 0.017 14.6 1.7 0.017 14.6 1.2 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain Reo_sigmaC PF04582.7 CDJ66863.1 - 0.41 9.7 51.5 0.0092 15.1 3.7 6.3 3 2 3 7 7 7 0 Reovirus sigma C capsid protein Pkinase PF00069.20 CDJ66865.1 - 5.9e-42 143.6 0.0 1.7e-27 96.1 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ66865.1 - 3.5e-17 62.3 0.0 2.3e-15 56.3 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.1 CDJ66865.1 - 1.9e-14 53.5 0.5 2.4e-07 30.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CDJ66865.1 - 6.2e-14 50.1 0.8 0.006 15.8 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CDJ66865.1 - 5.7e-10 38.2 4.5 0.0063 16.3 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CDJ66865.1 - 2.2e-08 33.5 3.1 0.13 11.9 0.2 4.4 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CDJ66865.1 - 1.6e-05 24.0 10.0 2.1 7.8 0.0 5.0 5 0 0 5 5 5 4 EF hand Kinase-like PF14531.1 CDJ66865.1 - 0.00055 18.9 0.0 0.65 8.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Neur_chan_memb PF02932.11 CDJ66865.1 - 2.8 7.7 9.5 15 5.3 0.2 2.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SET PF00856.23 CDJ66866.1 - 1.9e-18 67.3 0.0 1.9e-18 67.3 0.0 9.2 5 3 0 6 6 6 1 SET domain Bromodomain PF00439.20 CDJ66866.1 - 4.4e-14 52.1 0.0 9.7e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 CDJ66866.1 - 3.9e-05 23.2 2.3 3.9e-05 23.2 1.6 9.9 9 2 1 10 10 10 5 PHD-finger FYRN PF05964.9 CDJ66866.1 - 0.025 14.0 0.0 0.078 12.4 0.0 1.8 1 0 0 1 1 1 0 F/Y-rich N-terminus ABC_tran PF00005.22 CDJ66867.1 - 2.2e-42 144.6 27.4 6.8e-21 75.0 0.1 4.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CDJ66867.1 - 1.2e-22 81.2 0.0 1.6e-05 25.0 0.0 4.1 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 CDJ66867.1 - 9.8e-12 44.2 0.0 0.00012 21.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CDJ66867.1 - 3.7e-11 42.6 19.8 2.2e-06 27.0 3.7 4.3 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CDJ66867.1 - 1.1e-10 41.2 1.1 3.6e-05 23.2 0.1 3.1 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 CDJ66867.1 - 2.4e-09 37.6 0.8 0.0025 18.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 CDJ66867.1 - 6.1e-08 31.9 2.3 0.00034 19.5 0.0 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CDJ66867.1 - 9.6e-08 31.7 0.1 0.00089 18.7 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 CDJ66867.1 - 2.2e-07 31.3 1.1 5.4e-05 23.6 0.0 5.5 1 1 2 3 3 2 2 AAA domain IstB_IS21 PF01695.12 CDJ66867.1 - 2.9e-07 30.0 6.1 0.001 18.4 0.5 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_15 PF13175.1 CDJ66867.1 - 3.2e-07 29.7 0.0 0.15 11.0 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_33 PF13671.1 CDJ66867.1 - 6.2e-07 29.3 15.9 0.013 15.3 0.0 4.5 4 1 0 4 4 3 3 AAA domain GTP_EFTU PF00009.22 CDJ66867.1 - 7.5e-07 28.7 3.0 0.035 13.5 0.2 3.4 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CDJ66867.1 - 1.5e-06 27.7 0.9 0.0093 15.4 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CDJ66867.1 - 2.1e-06 27.6 0.0 0.014 15.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 CDJ66867.1 - 3.4e-06 27.8 2.2 0.0013 19.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CDJ66867.1 - 4e-06 26.4 0.9 0.13 11.6 0.0 3.6 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 CDJ66867.1 - 6.3e-06 26.4 0.0 0.19 11.9 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDJ66867.1 - 9.5e-06 25.3 1.8 0.0014 18.3 0.1 4.2 4 2 0 4 4 3 2 NACHT domain MobB PF03205.9 CDJ66867.1 - 2.1e-05 24.2 0.0 0.053 13.2 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CDJ66867.1 - 3.1e-05 23.8 0.6 0.3 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CDJ66867.1 - 3.5e-05 23.9 1.1 0.14 12.3 0.0 3.0 3 0 0 3 3 2 2 RNA helicase ArgK PF03308.11 CDJ66867.1 - 5.8e-05 22.0 3.3 0.038 12.7 0.0 3.0 3 0 0 3 3 2 2 ArgK protein DUF258 PF03193.11 CDJ66867.1 - 0.00011 21.3 14.8 0.0029 16.8 0.7 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 CDJ66867.1 - 0.00013 21.5 12.2 0.02 14.3 0.0 4.0 3 1 1 4 4 4 1 AAA-like domain AAA_5 PF07728.9 CDJ66867.1 - 0.00016 21.3 2.5 0.23 11.1 0.3 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Septin PF00735.13 CDJ66867.1 - 0.0002 20.4 8.8 0.0079 15.2 0.2 3.0 2 1 1 3 3 3 2 Septin Mg_chelatase PF01078.16 CDJ66867.1 - 0.00025 20.2 1.3 0.32 10.1 0.3 2.9 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 CDJ66867.1 - 0.00032 20.4 0.0 0.96 9.0 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_18 PF13238.1 CDJ66867.1 - 0.00038 20.7 0.0 0.056 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CDJ66867.1 - 0.0005 19.8 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 NTPase Arf PF00025.16 CDJ66867.1 - 0.00051 19.3 0.2 0.32 10.2 0.0 2.7 2 0 0 2 2 2 1 ADP-ribosylation factor family UPF0079 PF02367.12 CDJ66867.1 - 0.00059 19.4 1.1 0.2 11.3 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 CDJ66867.1 - 0.00097 18.8 21.4 0.013 15.2 0.0 5.5 4 1 0 4 4 3 2 Part of AAA domain MutS_V PF00488.16 CDJ66867.1 - 0.0014 18.1 0.1 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 MutS domain V AAA_22 PF13401.1 CDJ66867.1 - 0.0014 18.7 17.1 0.036 14.1 0.1 5.1 3 3 1 5 5 5 2 AAA domain NB-ARC PF00931.17 CDJ66867.1 - 0.0023 16.8 0.0 2.1 7.1 0.0 2.9 2 0 0 2 2 2 1 NB-ARC domain SRP54 PF00448.17 CDJ66867.1 - 0.0037 16.7 8.9 0.14 11.6 0.1 3.8 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 CDJ66867.1 - 0.0047 16.4 0.4 0.39 10.1 0.1 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.7 CDJ66867.1 - 0.0051 16.1 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein ATP_bind_1 PF03029.12 CDJ66867.1 - 0.01 15.3 0.0 2.7 7.4 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 CDJ66867.1 - 0.012 15.5 0.0 0.012 15.5 0.0 5.7 6 2 0 6 6 4 0 AAA domain SbcCD_C PF13558.1 CDJ66867.1 - 0.012 15.5 0.1 0.012 15.5 0.1 6.3 4 3 1 5 5 4 0 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.13 CDJ66867.1 - 0.061 12.5 0.2 7.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 CDJ66867.1 - 0.18 11.5 0.1 0.18 11.5 0.1 5.2 5 2 1 6 6 5 0 Dynamin family Bac_DnaA PF00308.13 CDJ66867.1 - 0.25 10.9 4.0 0.2 11.2 0.1 2.5 3 0 0 3 3 2 0 Bacterial dnaA protein PRK PF00485.13 CDJ66867.1 - 0.25 10.8 1.8 13 5.3 0.1 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.1 CDJ66867.1 - 0.35 10.4 8.4 0.52 9.8 0.0 3.6 3 1 0 4 4 4 0 AAA domain AAA_13 PF13166.1 CDJ66867.1 - 0.77 8.1 0.0 0.77 8.1 0.0 4.9 4 1 1 5 5 5 0 AAA domain Thymidylate_kin PF02223.12 CDJ66867.1 - 1.9 7.8 11.3 1.2 8.5 0.6 3.7 4 0 0 4 4 4 0 Thymidylate kinase DUF87 PF01935.12 CDJ66867.1 - 8.5 6.1 0.0 8.5 6.1 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function DUF87 His_Phos_1 PF00300.17 CDJ66868.1 - 8.9e-16 58.3 1.3 9.5e-15 55.0 1.1 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF4518 PF15008.1 CDJ66870.1 - 0.018 14.0 0.1 0.026 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) FimP PF09766.4 CDJ66870.1 - 0.42 9.6 4.7 0.65 9.0 3.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 CDJ66870.1 - 1.7 6.7 11.3 2.2 6.3 7.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HEAT PF02985.17 CDJ66871.1 - 1.7e-16 58.7 23.4 4.6e-05 23.1 0.0 10.3 11 0 0 11 11 10 4 HEAT repeat HEAT_2 PF13646.1 CDJ66871.1 - 4.4e-14 52.5 41.4 1.6e-10 41.0 0.0 9.5 6 3 3 9 9 9 5 HEAT repeats Vac14_Fab1_bd PF12755.2 CDJ66871.1 - 2.3e-12 47.1 1.0 0.00052 20.3 0.0 5.8 5 1 1 7 7 6 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CDJ66871.1 - 9.2e-09 35.5 1.1 4.3e-06 27.0 0.0 12.6 11 5 5 16 16 12 4 HEAT-like repeat Adaptin_N PF01602.15 CDJ66871.1 - 9.6e-05 20.8 0.2 0.01 14.2 0.1 3.2 2 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.2 CDJ66871.1 - 0.00011 22.1 0.0 0.0049 16.7 0.0 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 CDJ66871.1 - 0.0003 20.2 0.5 0.0091 15.3 0.0 3.5 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.18 CDJ66871.1 - 0.0006 19.5 19.0 2.7 7.9 0.0 8.4 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat DUF2454 PF10521.4 CDJ66871.1 - 0.0056 15.7 0.1 5.1 6.0 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) Xpo1 PF08389.7 CDJ66871.1 - 0.0087 15.9 2.2 3.1 7.6 0.0 3.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 CDJ66871.1 - 7.2 6.6 8.0 7.5 6.5 0.4 4.7 5 1 0 5 5 5 0 Importin-beta N-terminal domain Prefoldin_2 PF01920.15 CDJ66872.1 - 8.9e-19 67.2 2.8 8.9e-19 67.2 2.0 1.6 2 0 0 2 2 1 1 Prefoldin subunit Prefoldin PF02996.12 CDJ66872.1 - 4.3e-05 23.1 0.9 0.075 12.6 0.0 2.2 2 0 0 2 2 2 2 Prefoldin subunit Filament PF00038.16 CDJ66872.1 - 0.0033 16.9 4.9 0.013 14.9 0.4 2.2 2 0 0 2 2 2 1 Intermediate filament protein DASH_Dad3 PF08656.5 CDJ66872.1 - 0.0075 15.9 4.2 0.034 13.8 0.7 2.3 2 0 0 2 2 2 1 DASH complex subunit Dad3 DUF3158 PF11358.3 CDJ66872.1 - 0.013 15.0 2.4 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3158) Spc24 PF08286.6 CDJ66872.1 - 0.013 15.1 5.6 0.17 11.5 0.7 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.5 CDJ66872.1 - 0.014 15.5 2.9 1.3 9.1 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.4 CDJ66872.1 - 0.015 13.8 4.7 0.02 13.4 3.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1043 PF06295.7 CDJ66872.1 - 0.035 13.7 0.3 0.035 13.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF615 PF04751.9 CDJ66872.1 - 0.047 13.3 4.6 0.069 12.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) TMF_DNA_bd PF12329.3 CDJ66872.1 - 0.05 13.4 1.0 0.05 13.4 0.7 2.5 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 CDJ66872.1 - 0.052 13.2 2.4 1 9.0 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding XhlA PF10779.4 CDJ66872.1 - 0.064 13.1 3.4 5.6 6.9 0.2 2.4 2 0 0 2 2 2 0 Haemolysin XhlA GAS PF13851.1 CDJ66872.1 - 0.071 12.2 4.6 0.89 8.7 0.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1319 PF07028.6 CDJ66872.1 - 0.11 12.6 2.7 3.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) NYD-SP28 PF14772.1 CDJ66872.1 - 0.13 12.3 5.3 0.21 11.7 0.0 2.4 3 0 0 3 3 2 0 Sperm tail Cep57_MT_bd PF06657.8 CDJ66872.1 - 0.14 12.0 4.1 4.3 7.3 0.6 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Ax_dynein_light PF10211.4 CDJ66872.1 - 0.16 11.7 5.8 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Exonuc_VII_L PF02601.10 CDJ66872.1 - 0.18 10.9 3.1 0.24 10.5 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3138 PF11336.3 CDJ66872.1 - 0.2 9.8 7.0 0.3 9.1 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1664 PF07889.7 CDJ66872.1 - 0.23 11.2 4.6 0.34 10.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 CDJ66872.1 - 0.36 11.1 4.5 8.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 CDJ66872.1 - 0.45 10.9 11.1 0.6 10.5 1.1 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) M_domain PF12938.2 CDJ66872.1 - 0.56 9.9 7.8 4 7.1 5.6 1.9 1 1 1 2 2 2 0 M domain of GW182 APG6 PF04111.7 CDJ66872.1 - 0.58 9.1 8.5 1 8.3 0.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2802 PF10975.3 CDJ66872.1 - 0.67 9.7 8.2 0.82 9.4 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) Cob_adeno_trans PF01923.13 CDJ66872.1 - 0.68 9.7 3.2 0.83 9.4 0.8 1.8 2 0 0 2 2 2 0 Cobalamin adenosyltransferase AATF-Che1 PF13339.1 CDJ66872.1 - 0.71 10.0 9.1 4.1 7.5 0.2 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4200 PF13863.1 CDJ66872.1 - 0.73 9.7 9.5 4.1 7.3 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GrpE PF01025.14 CDJ66872.1 - 1 8.8 5.9 3.5 7.1 1.1 2.1 2 0 0 2 2 2 0 GrpE Cep57_CLD PF14073.1 CDJ66872.1 - 1.1 9.0 9.4 2.6 7.8 6.5 1.7 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 WXG100 PF06013.7 CDJ66872.1 - 1.1 9.2 11.4 0.45 10.5 4.4 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Herpes_BLRF2 PF05812.7 CDJ66872.1 - 1.3 8.8 6.4 2.2 8.0 0.3 2.1 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein MscS_porin PF12795.2 CDJ66872.1 - 1.6 8.0 19.3 0.33 10.2 1.7 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain IncA PF04156.9 CDJ66872.1 - 1.7 8.2 11.7 5.9 6.4 1.1 2.1 1 1 0 1 1 1 0 IncA protein Apolipoprotein PF01442.13 CDJ66872.1 - 1.9 7.9 12.2 20 4.6 8.4 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain COG2 PF06148.6 CDJ66872.1 - 1.9 8.3 5.2 0.9 9.4 0.7 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMCO5 PF14992.1 CDJ66872.1 - 3 6.9 6.4 41 3.1 4.4 2.0 1 1 0 1 1 1 0 TMCO5 family Seryl_tRNA_N PF02403.17 CDJ66872.1 - 3.7 7.6 9.1 6.3 6.8 0.5 2.5 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.1 CDJ66872.1 - 4.4 7.5 8.5 2.2 8.4 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) CENP-Q PF13094.1 CDJ66872.1 - 5.5 6.9 10.9 0.54 10.2 4.4 1.7 2 1 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CASP_C PF08172.7 CDJ66872.1 - 7.8 5.4 10.5 4.4 6.2 0.8 2.1 2 0 0 2 2 2 0 CASP C terminal HAUS-augmin3 PF14932.1 CDJ66872.1 - 8.2 5.5 9.1 41 3.2 6.3 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DivIC PF04977.10 CDJ66872.1 - 9.8 5.7 14.1 2.5 7.6 1.9 2.9 3 0 0 3 3 3 0 Septum formation initiator RNA_pol_Rpb1_5 PF04998.12 CDJ66873.1 - 6.6 5.8 0.0 6.6 5.8 0.0 8.0 3 2 2 5 5 5 0 RNA polymerase Rpb1, domain 5 PAT1 PF09770.4 CDJ66874.1 - 4.6 5.3 32.6 5.3 5.1 22.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 R_equi_Vir PF05526.6 CDJ66874.1 - 5.1 6.6 10.1 10 5.7 7.0 1.6 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein VIT1 PF01988.14 CDJ66874.1 - 6.1 6.2 9.6 14 5.0 6.7 1.7 1 0 0 1 1 1 0 VIT family Parvo_coat PF00740.13 CDJ66874.1 - 8.7 5.1 14.5 13 4.5 10.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Spore_coat_CotO PF14153.1 CDJ66875.1 - 0.0002 20.8 4.0 0.0002 20.8 2.8 3.0 3 0 0 3 3 3 1 Spore coat protein CotO OmpH PF03938.9 CDJ66875.1 - 0.008 16.1 21.9 0.008 16.1 15.2 5.5 5 2 0 5 5 5 1 Outer membrane protein (OmpH-like) Zip PF02535.17 CDJ66875.1 - 6.9 5.5 9.6 3.6 6.5 1.5 3.0 3 0 0 3 3 3 0 ZIP Zinc transporter Ycf1 PF05758.7 CDJ66875.1 - 6.9 4.2 22.8 0.018 12.8 0.4 2.1 2 0 0 2 2 2 0 Ycf1 LRR_6 PF13516.1 CDJ66876.1 - 9.3e-13 46.8 11.0 0.11 12.6 0.0 8.9 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.2 CDJ66876.1 - 2e-09 36.8 11.3 0.0018 17.8 0.0 4.8 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CDJ66876.1 - 0.0005 19.8 9.1 22 5.8 0.0 7.2 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 CDJ66876.1 - 0.0037 17.0 11.6 6.9 7.1 0.0 7.0 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 CDJ66876.1 - 0.011 15.4 19.7 0.013 15.2 1.6 5.0 2 2 3 5 5 5 0 Leucine rich repeat Phage_pRha PF09669.5 CDJ66877.1 - 0.6 10.5 3.5 2.6 8.4 2.4 2.1 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) SRP54 PF00448.17 CDJ66878.1 - 1.6e-76 256.1 0.1 3e-76 255.2 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CDJ66878.1 - 8.9e-30 103.0 7.9 1.1e-29 102.7 1.4 2.7 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 CDJ66878.1 - 4.5e-09 36.2 0.2 8.4e-08 32.2 0.0 2.8 3 0 0 3 3 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 CDJ66878.1 - 2.2e-07 30.8 0.0 5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CDJ66878.1 - 8.3e-06 25.3 0.2 3.7e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 CDJ66878.1 - 8.7e-06 25.2 0.1 4e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 CDJ66878.1 - 5.2e-05 22.9 0.2 0.00016 21.3 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CDJ66878.1 - 0.00065 18.5 0.8 0.0066 15.2 0.0 2.8 4 0 0 4 4 4 1 ArgK protein AAA_16 PF13191.1 CDJ66878.1 - 0.00089 19.2 0.2 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_31 PF13614.1 CDJ66878.1 - 0.0014 18.5 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CDJ66878.1 - 0.0015 18.7 0.4 0.011 15.8 0.0 2.7 3 2 0 3 3 2 1 AAA domain AAA_30 PF13604.1 CDJ66878.1 - 0.0038 16.8 0.1 0.0038 16.8 0.1 2.0 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 CDJ66878.1 - 0.0039 16.8 0.1 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 CDJ66878.1 - 0.0044 16.1 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin SRPRB PF09439.5 CDJ66878.1 - 0.0074 15.5 0.3 2.8 7.1 0.0 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 CDJ66878.1 - 0.012 16.4 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CDJ66878.1 - 0.013 14.5 0.0 0.043 12.9 0.0 1.9 1 0 0 1 1 1 0 KaiC Methyltransf_24 PF13578.1 CDJ66878.1 - 0.026 15.3 0.0 0.069 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ATP_bind_1 PF03029.12 CDJ66878.1 - 0.03 13.8 0.3 0.15 11.6 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 CDJ66878.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase AAA_25 PF13481.1 CDJ66878.1 - 0.059 12.7 0.3 0.27 10.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CDJ66878.1 - 0.066 12.7 0.5 3.8 7.0 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_pol PF00940.14 CDJ66878.1 - 0.073 11.5 0.5 0.13 10.6 0.3 1.3 1 0 0 1 1 1 0 DNA-dependent RNA polymerase DUF2209 PF09974.4 CDJ66878.1 - 0.087 12.9 0.3 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_28 PF13521.1 CDJ66878.1 - 0.11 12.4 0.6 0.31 10.9 0.2 2.0 2 1 0 2 2 2 0 AAA domain SR-25 PF10500.4 CDJ66878.1 - 0.2 11.0 10.1 0.41 10.0 7.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tis11B_N PF04553.7 CDJ66879.1 - 0.13 12.4 1.7 0.31 11.2 0.1 2.4 2 0 0 2 2 2 0 Tis11B like protein, N terminus Brix PF04427.13 CDJ66881.1 - 3.3e-29 101.9 0.4 2.2e-27 95.9 0.3 2.2 1 1 0 1 1 1 1 Brix domain SR-25 PF10500.4 CDJ66881.1 - 0.00063 19.2 10.4 0.00063 19.2 7.2 6.0 4 2 1 5 5 5 2 Nuclear RNA-splicing-associated protein SLA_LP_auto_ag PF05889.8 CDJ66883.1 - 0.03 12.8 0.1 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) PSK_trans_fac PF07704.6 CDJ66883.1 - 0.28 11.9 0.0 0.28 11.9 0.0 2.4 2 1 0 2 2 2 0 Rv0623-like transcription factor Gag_spuma PF03276.9 CDJ66883.1 - 0.28 9.4 14.2 0.38 9.0 9.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein CENP-T PF15511.1 CDJ66883.1 - 0.29 10.3 16.6 0.38 9.9 11.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Plasmodium_Vir PF05795.6 CDJ66883.1 - 0.5 9.5 3.6 0.42 9.7 1.4 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PIH1 PF08190.7 CDJ66883.1 - 0.83 9.0 13.0 1.2 8.4 9.0 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CDC45 PF02724.9 CDJ66883.1 - 1 7.3 11.1 1.3 6.9 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDJ66883.1 - 1.7 6.2 11.7 2.6 5.6 8.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3306 PF11748.3 CDJ66883.1 - 2.8 8.6 13.5 7.7 7.2 9.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Daxx PF03344.10 CDJ66883.1 - 3.2 6.1 18.4 4.2 5.7 12.7 1.1 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 CDJ66883.1 - 3.4 7.4 8.8 4.8 6.9 6.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF4175 PF13779.1 CDJ66883.1 - 4.5 4.8 23.3 6.1 4.4 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RR_TM4-6 PF06459.7 CDJ66883.1 - 5.7 6.7 17.3 7.6 6.3 12.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex16 PF08610.5 CDJ66883.1 - 7.2 5.5 8.4 11 4.9 5.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF2201_N PF13203.1 CDJ66883.1 - 8.6 5.4 14.4 12 4.9 10.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain eIF2_C PF09173.6 CDJ66884.1 - 9.8e-30 102.4 0.2 1.1e-29 102.2 0.1 1.0 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal BAF1_ABF1 PF04684.8 CDJ66885.1 - 0.0031 16.4 9.0 0.0031 16.4 6.2 2.3 2 1 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDJ66885.1 - 0.048 11.8 20.4 0.056 11.6 14.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ66885.1 - 0.059 13.7 2.2 0.059 13.7 1.5 3.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein Cse1 PF08506.5 CDJ66885.1 - 0.18 10.3 2.1 0.26 9.8 1.4 1.1 1 0 0 1 1 1 0 Cse1 CAF1-p150_C2 PF15539.1 CDJ66885.1 - 0.45 9.5 4.5 0.75 8.8 3.1 1.4 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Activator_LAG-3 PF11498.3 CDJ66885.1 - 0.51 9.0 24.5 0.62 8.7 17.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SoxE PF06525.6 CDJ66886.1 - 0.25 10.6 3.6 3.7 6.7 0.2 2.4 2 0 0 2 2 2 0 Sulfocyanin (SoxE) DUF778 PF05608.7 CDJ66886.1 - 0.26 11.2 6.5 6.9 6.6 0.1 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF778) Dehydrin PF00257.14 CDJ66886.1 - 0.26 11.5 0.1 0.26 11.5 0.0 6.3 4 2 0 5 5 5 0 Dehydrin BAF1_ABF1 PF04684.8 CDJ66887.1 - 0.0049 15.7 19.5 0.0049 15.7 13.6 2.8 2 1 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 CDJ66887.1 - 1.1 7.4 55.7 0.44 8.7 18.0 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.10 CDJ66887.1 - 1.7 7.7 18.1 0.5 9.5 2.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Peptidase_C58 PF03543.9 CDJ66887.1 - 9.1 5.7 28.1 4.4 6.7 8.4 2.2 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen RRM_1 PF00076.17 CDJ66888.1 - 2e-17 62.5 0.0 4.3e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ66888.1 - 2.5e-14 53.0 0.0 6.5e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ66888.1 - 1.7e-07 30.9 0.0 5.1e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDJ66888.1 - 0.031 14.0 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Sin_N PF04801.8 CDJ66889.1 - 5.8e-44 150.6 24.0 1.3e-36 126.3 13.9 5.1 1 1 1 2 2 2 2 Sin-like protein conserved region RF-1 PF00472.15 CDJ66889.1 - 9.5e-10 38.2 5.6 9.5e-10 38.2 3.9 3.9 5 0 0 5 5 5 1 RF-1 domain XPG_N PF00752.12 CDJ66890.1 - 4.3e-12 46.1 0.6 9.7e-11 41.8 0.0 3.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 CDJ66890.1 - 2.2e-07 30.8 0.2 2e-06 27.7 0.2 2.8 1 0 0 1 1 1 1 XPG I-region BAF1_ABF1 PF04684.8 CDJ66890.1 - 0.0016 17.3 10.6 0.0016 17.3 7.4 13.8 7 4 5 13 13 13 3 BAF1 / ABF1 chromatin reorganising factor MIP-T3 PF10243.4 CDJ66891.1 - 2.9 6.2 51.3 3.2 6.0 35.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SART-1 PF03343.8 CDJ66891.1 - 7 4.8 34.5 8.5 4.5 23.9 1.0 1 0 0 1 1 1 0 SART-1 family Ndc1_Nup PF09531.5 CDJ66892.1 - 0.65 8.3 26.6 0.77 8.1 18.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF572 PF04502.8 CDJ66892.1 - 1.2 8.2 35.7 1.5 7.9 24.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.4 CDJ66892.1 - 3.7 5.6 68.3 5.1 5.2 47.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDJ66893.1 - 0.0055 16.1 12.7 0.0055 16.1 8.8 7.1 6 1 1 7 7 7 3 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cwf_Cwc_15 PF04889.7 CDJ66893.1 - 0.0083 15.8 8.9 0.0083 15.8 6.1 7.2 6 3 0 6 6 6 2 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.27 CDJ66893.1 - 0.18 11.7 17.1 0.42 10.5 2.2 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Suf PF05843.9 CDJ66894.1 - 2.4 7.8 44.4 0.037 13.7 1.4 4.1 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) GN3L_Grn1 PF08701.6 CDJ66894.1 - 2.9 7.8 0.0 2.9 7.8 0.0 4.4 4 0 0 4 4 4 0 GNL3L/Grn1 putative GTPase DUF359 PF04019.7 CDJ66895.1 - 0.05 12.9 4.8 0.063 12.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF359) SR-25 PF10500.4 CDJ66895.1 - 0.3 10.5 81.7 0.025 14.0 14.8 4.6 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein SOUL PF04832.7 CDJ66896.1 - 4.7e-28 97.8 3.0 2e-20 73.0 0.1 2.4 3 0 0 3 3 3 2 SOUL heme-binding protein Suf PF05843.9 CDJ66896.1 - 0.0068 16.1 4.6 0.0074 16.0 3.2 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) OmpH PF03938.9 CDJ66896.1 - 0.064 13.2 13.9 0.099 12.5 9.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BRF1 PF07741.8 CDJ66896.1 - 0.32 11.2 12.7 1.6 8.9 7.5 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Spt20 PF12090.3 CDJ66897.1 - 0.0034 16.7 11.4 0.11 11.8 2.3 2.2 2 0 0 2 2 2 2 Spt20 family RAB3GAP2_N PF14655.1 CDJ66897.1 - 0.012 14.6 0.9 0.012 14.6 0.6 2.6 2 1 0 2 2 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-DHHC PF01529.15 CDJ66897.1 - 0.025 13.9 2.4 0.22 10.8 0.3 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase 53-BP1_Tudor PF09038.5 CDJ66897.1 - 0.051 13.3 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Suf PF05843.9 CDJ66897.1 - 0.13 11.9 17.8 0.086 12.5 5.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.9 CDJ66897.1 - 0.7 9.4 9.3 0.81 9.2 0.1 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FCP1_C PF09309.5 CDJ66897.1 - 0.73 9.0 27.7 0.91 8.7 10.1 2.3 2 0 0 2 2 2 0 FCP1, C-terminal Dala_Dala_lig_N PF01820.16 CDJ66897.1 - 0.81 10.0 4.0 4.6 7.5 0.4 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus NAD_binding_11 PF14833.1 CDJ66897.1 - 1.5 8.8 7.9 0.074 13.1 1.2 2.0 2 0 0 2 2 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Neur_chan_memb PF02932.11 CDJ66897.1 - 1.8 8.4 9.9 3.4 7.4 6.9 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XAP5 PF04921.9 CDJ66897.1 - 1.8 8.0 16.4 4.9 6.6 6.1 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator FHIPEP PF00771.15 CDJ66897.1 - 3.2 5.9 7.9 3 6.0 1.5 2.0 2 0 0 2 2 2 0 FHIPEP family RNA_pol_Rbc25 PF08292.7 CDJ66897.1 - 3.8 7.7 9.3 2.7 8.2 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Presenilin PF01080.12 CDJ66897.1 - 4.1 6.1 11.6 5.8 5.6 3.8 2.1 2 0 0 2 2 2 0 Presenilin DUF4557 PF15101.1 CDJ66897.1 - 4.8 6.9 23.7 1.9 8.2 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Med15 PF09606.5 CDJ66897.1 - 5.6 5.0 58.4 1.2 7.2 13.4 2.1 1 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SPX PF03105.14 CDJ66897.1 - 6.3 6.5 17.4 7.6 6.2 0.3 2.1 2 0 0 2 2 2 0 SPX domain Peptidase_S15 PF02129.13 CDJ66897.1 - 7 5.9 15.2 1.2 8.5 4.6 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) CPSF100_C PF13299.1 CDJ66897.1 - 7.4 6.7 12.4 1.2 9.2 2.9 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.9 CDJ66897.1 - 8.4 4.2 20.5 0.88 7.5 8.0 2.2 2 0 0 2 2 2 0 CDC45-like protein Band_3_cyto PF07565.8 CDJ66897.1 - 9.7 5.6 15.5 6.7 6.1 0.2 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Pkinase PF00069.20 CDJ66898.1 - 4e-35 121.2 7.0 2.1e-13 50.0 0.0 5.7 3 2 3 6 6 6 4 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ66898.1 - 1.1e-15 57.4 10.0 2.9e-09 36.3 2.8 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase DUF605 PF04652.11 CDJ66898.1 - 0.0058 16.0 20.7 0.0058 16.0 14.4 3.6 3 1 0 3 3 3 1 Vta1 like TFIIA PF03153.8 CDJ66898.1 - 0.0073 16.2 21.0 0.0073 16.2 14.5 3.2 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ66898.1 - 0.27 9.4 145.8 0.0065 14.7 29.4 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Chromo PF00385.19 CDJ66900.1 - 1e-13 50.7 0.0 1.3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AP2 PF00847.15 CDJ66901.1 - 3.5e-13 49.4 4.7 3.1e-10 40.0 0.1 2.6 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.1 CDJ66901.1 - 5.1e-06 26.5 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AP2-coincident C-terminal Got1 PF04178.7 CDJ66902.1 - 2.1e-27 95.5 9.6 2.9e-27 95.1 6.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Ribosomal_L34e PF01199.13 CDJ66903.1 - 2.8e-32 110.7 5.7 2.8e-32 110.7 4.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L34e PLATZ PF04640.9 CDJ66903.1 - 1.1 9.5 4.6 1.3 9.2 0.0 2.7 2 1 1 3 3 3 0 PLATZ transcription factor FhuF_C PF11575.3 CDJ66903.1 - 1.1 8.9 5.0 14 5.4 0.2 2.8 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain PDGF PF00341.12 CDJ66903.1 - 1.6 8.8 5.7 4.6 7.4 1.4 2.3 2 0 0 2 2 2 0 PDGF/VEGF domain DUF3133 PF11331.3 CDJ66903.1 - 3.8 7.1 5.9 1.2 8.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) FtsJ PF01728.14 CDJ66904.1 - 1.9e-53 181.1 0.0 2.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase NSP13 PF06460.7 CDJ66904.1 - 0.00037 19.4 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 Coronavirus NSP13 Methyltransf_18 PF12847.2 CDJ66904.1 - 0.00057 20.4 0.0 0.00088 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ66904.1 - 0.00082 18.9 0.0 0.0048 16.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ66904.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ66904.1 - 0.11 12.8 0.3 0.45 10.9 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain SH3_9 PF14604.1 CDJ66904.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain NUDIX_2 PF13869.1 CDJ66906.1 - 2e-54 183.8 0.0 2.5e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase DUF667 PF05018.8 CDJ66907.1 - 0.00017 20.8 0.2 0.00022 20.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) HSDR_N_2 PF13588.1 CDJ66907.1 - 0.053 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Adap_comp_sub PF00928.16 CDJ66907.1 - 0.11 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family GvpK PF05121.7 CDJ66908.1 - 0.056 13.2 0.4 0.097 12.5 0.3 1.3 1 0 0 1 1 1 0 Gas vesicle protein K UL11 PF11094.3 CDJ66909.1 - 0.2 11.4 8.8 0.77 9.6 0.0 4.2 4 0 0 4 4 4 0 Membrane-associated tegument protein Ribosomal_60s PF00428.14 CDJ66910.1 - 0.015 15.6 21.1 0.45 10.9 2.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Shadoo PF14999.1 CDJ66910.1 - 0.018 14.8 14.9 0.23 11.3 0.8 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RskA PF10099.4 CDJ66910.1 - 0.026 14.2 16.4 0.28 10.9 1.1 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Kelch_4 PF13418.1 CDJ66910.1 - 0.044 13.5 0.2 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain CDK2AP PF09806.4 CDJ66910.1 - 0.33 11.1 3.2 5 7.2 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Med3 PF11593.3 CDJ66910.1 - 0.41 9.8 7.2 0.8 8.8 0.6 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Gly-zipper_OmpA PF13436.1 CDJ66910.1 - 3.6 7.2 15.0 3.1 7.4 1.7 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Peptidase_M22 PF00814.20 CDJ66911.1 - 5.4e-77 258.8 0.3 4.9e-74 249.1 0.2 2.1 1 1 0 1 1 1 1 Glycoprotease family FGGY_N PF00370.16 CDJ66911.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain ATP-synt_C PF00137.16 CDJ66912.1 - 4e-29 100.3 31.5 2.8e-16 59.1 8.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PT-VENN PF04829.8 CDJ66912.1 - 2.1 7.9 7.0 1.7 8.2 3.3 2.1 1 1 1 2 2 2 0 Pre-toxin domain with VENN motif GerA PF03323.8 CDJ66912.1 - 3.9 5.4 6.8 6 4.8 0.3 2.3 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF2592 PF10766.4 CDJ66912.1 - 4.4 6.7 9.6 0.45 9.8 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) Mtc PF03820.12 CDJ66913.1 - 5.9e-50 169.6 0.5 5.9e-40 136.8 0.2 2.0 1 1 1 2 2 2 2 Tricarboxylate carrier DUF2567 PF10821.3 CDJ66913.1 - 0.00096 18.7 1.0 0.0014 18.1 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) Activator_LAG-3 PF11498.3 CDJ66914.1 - 0.28 9.8 13.7 0.35 9.5 9.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Surface_antigen PF11054.3 CDJ66915.1 - 6e-61 206.0 1.6 3.4e-59 200.2 1.1 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Sod_Fe_N PF00081.17 CDJ66916.1 - 1.2e-23 83.1 0.3 1.3e-23 83.0 0.2 1.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Transaldolase PF00923.14 CDJ66917.1 - 4.3e-10 39.2 0.2 5.9e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 Transaldolase GFO_IDH_MocA PF01408.17 CDJ66917.1 - 0.32 11.5 5.0 0.79 10.2 0.2 2.0 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SASRP1 PF15160.1 CDJ66917.1 - 0.52 9.4 2.5 0.64 9.2 1.7 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Ribosomal_60s PF00428.14 CDJ66917.1 - 1.9 8.9 21.7 0.066 13.6 8.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-F_N PF10481.4 CDJ66917.1 - 6.2 6.1 7.2 5.2 6.3 0.1 2.0 1 1 1 2 2 2 0 Cenp-F N-terminal domain SR-25 PF10500.4 CDJ66917.1 - 6.2 6.2 17.1 0.65 9.4 8.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Adaptin_N PF01602.15 CDJ66918.1 - 2.8e-39 134.8 5.6 3.6e-39 134.5 3.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CDJ66918.1 - 7.3e-07 29.3 0.0 7.3e-07 29.3 0.0 3.5 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.17 CDJ66918.1 - 2e-05 24.2 1.0 0.26 11.4 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 CDJ66918.1 - 0.00017 21.5 1.6 0.00046 20.0 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 CDJ66918.1 - 0.0028 17.5 0.2 0.96 9.3 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Rpn3_C PF08375.6 CDJ66918.1 - 0.069 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal HEAT_PBS PF03130.11 CDJ66918.1 - 0.21 12.1 0.1 0.21 12.1 0.1 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CDJ66918.1 - 0.38 11.3 0.0 0.38 11.3 0.0 5.2 2 2 4 6 6 6 0 HEAT-like repeat Arm PF00514.18 CDJ66918.1 - 1 9.3 0.0 1 9.3 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pro_isomerase PF00160.16 CDJ66920.1 - 5.5e-07 29.9 0.0 6.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RskA PF10099.4 CDJ66920.1 - 0.024 14.3 5.4 0.033 13.9 3.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA PI-PLC-X PF00388.14 CDJ66922.1 - 6.4e-32 109.9 0.0 1.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.6 CDJ66922.1 - 1.4e-05 25.0 0.1 1.4e-05 25.0 0.1 1.6 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Spc7 PF08317.6 CDJ66923.1 - 0.062 11.9 8.0 0.069 11.8 5.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 CDJ66923.1 - 0.19 11.7 15.3 0.026 14.5 5.8 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IpgD PF05925.7 CDJ66923.1 - 0.42 8.7 3.3 0.44 8.7 2.3 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD FUSC PF04632.7 CDJ66923.1 - 0.6 8.4 14.0 0.7 8.2 9.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.4 CDJ66923.1 - 6.4 5.6 16.2 8.1 5.2 11.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Baculo_gp64 PF03273.8 CDJ66924.1 - 0.091 10.9 1.6 0.11 10.5 1.1 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family SNF2_N PF00176.18 CDJ66928.1 - 3.5e-35 121.2 0.0 4e-30 104.6 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CDJ66928.1 - 5.1e-08 32.6 1.4 1.2e-07 31.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 CDJ66928.1 - 8.5e-07 28.8 6.2 8.5e-07 28.8 4.3 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ66928.1 - 2.1e-06 27.4 12.7 2.1e-06 27.4 8.8 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CDJ66928.1 - 0.00056 19.5 11.1 0.00067 19.2 4.3 3.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDJ66928.1 - 0.0006 19.6 7.1 0.0006 19.6 4.9 3.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CDJ66928.1 - 0.0012 18.5 13.7 0.0012 18.5 9.5 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CDJ66928.1 - 0.002 17.7 9.0 0.002 17.7 6.3 2.2 1 1 0 1 1 1 1 RING-type zinc-finger AP2 PF00847.15 CDJ66929.1 - 1.8e-09 37.5 3.3 1.5e-05 25.0 0.3 6.4 7 0 0 7 7 7 2 AP2 domain FDF PF09532.5 CDJ66930.1 - 0.02 15.4 0.7 0.022 15.2 0.5 1.0 1 0 0 1 1 1 0 FDF domain DUF3529 PF12046.3 CDJ66930.1 - 0.037 13.0 0.0 0.04 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) Pro_isomerase PF00160.16 CDJ66931.1 - 2.3e-30 105.8 0.0 9.4e-30 103.8 0.0 2.1 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 CDJ66931.1 - 0.00046 19.7 13.9 0.00046 19.7 9.6 3.1 2 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDJ66931.1 - 0.0065 16.8 13.5 0.0065 16.8 9.4 4.5 5 0 0 5 5 5 1 60s Acidic ribosomal protein KH_1 PF00013.24 CDJ66933.1 - 4.7e-19 67.8 0.0 8.2e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CDJ66933.1 - 1.2e-12 47.1 1.3 5.7e-07 29.0 0.0 2.8 3 0 0 3 3 3 2 KH domain KH_4 PF13083.1 CDJ66933.1 - 4.2e-06 26.2 0.8 0.041 13.5 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CDJ66933.1 - 0.00024 20.6 0.1 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 CDJ66933.1 - 0.24 11.2 0.7 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 NusA-like KH domain Tat PF00539.13 CDJ66934.1 - 0.74 9.4 5.0 1 9.0 3.5 1.2 1 0 0 1 1 1 0 Transactivating regulatory protein (Tat) Retrotrans_gag PF03732.12 CDJ66935.1 - 0.012 15.6 0.2 0.059 13.4 0.0 2.1 1 1 1 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.1 CDJ66936.1 - 4.8e-10 39.8 0.0 9.8e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ66936.1 - 4.1e-09 36.1 0.0 8.8e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ66936.1 - 7.2e-06 25.8 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 CDJ66936.1 - 3.4e-05 23.2 0.0 9.3e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 CDJ66936.1 - 0.00014 21.4 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CDJ66936.1 - 0.0016 18.4 0.0 0.0079 16.1 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Histone PF00125.19 CDJ66937.1 - 2.7e-18 65.8 0.1 3.6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 CDJ66937.1 - 0.00019 21.6 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 CDJ66937.1 - 0.0012 18.9 0.1 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1079 PF06435.6 CDJ66938.1 - 7.3 6.6 6.9 1.3 9.0 1.6 1.9 1 1 1 2 2 2 0 Repeat of unknown function (DUF1079) SR-25 PF10500.4 CDJ66940.1 - 0.00044 19.8 8.5 0.00044 19.8 5.9 3.0 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1645 PF07816.6 CDJ66941.1 - 0.0029 18.0 3.4 0.004 17.6 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) AF-4 PF05110.8 CDJ66941.1 - 0.09 10.6 5.6 0.098 10.5 3.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.6 CDJ66941.1 - 0.3 9.1 1.0 0.33 8.9 0.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_L1 PF00687.16 CDJ66942.1 - 3e-10 39.8 0.0 8.1e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family MAT1 PF06391.8 CDJ66943.1 - 6.4e-08 32.4 14.0 6.4e-08 32.4 9.7 2.5 2 1 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 CDJ66943.1 - 4e-05 23.2 11.2 8.8e-05 22.1 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Pex14_N PF04695.8 CDJ66943.1 - 0.00047 20.2 0.2 0.00047 20.2 0.1 2.9 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_2 PF13639.1 CDJ66943.1 - 0.0032 17.2 10.5 0.0076 16.0 7.3 1.7 1 0 0 1 1 1 1 Ring finger domain SSP160 PF06933.6 CDJ66943.1 - 0.0074 14.3 9.5 0.0092 14.0 6.6 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF1673 PF07895.6 CDJ66943.1 - 0.037 13.5 6.6 0.065 12.7 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) zf-C3HC4_2 PF13923.1 CDJ66943.1 - 0.075 13.0 8.6 0.24 11.4 6.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 CDJ66943.1 - 0.11 11.9 0.0 0.11 11.9 0.0 2.7 4 0 0 4 4 3 0 Rad50 zinc hook motif zf-C3HC4 PF00097.20 CDJ66943.1 - 0.12 12.0 10.0 0.39 10.4 6.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_pol_viral_N PF00242.12 CDJ66943.1 - 0.15 11.0 14.5 0.26 10.2 10.1 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2207 PF09972.4 CDJ66943.1 - 0.18 10.3 6.4 0.25 9.8 3.8 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) BatA PF07584.6 CDJ66943.1 - 0.35 11.0 14.3 1.1 9.4 9.9 1.9 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal DUF1675 PF07897.6 CDJ66943.1 - 0.6 9.9 15.3 0.97 9.2 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) AF-4 PF05110.8 CDJ66943.1 - 3.2 5.4 25.7 4.7 4.9 17.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UPF0118 PF01594.11 CDJ66946.1 - 0.00071 18.6 0.0 0.00077 18.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF20 DUF2688 PF10892.3 CDJ66946.1 - 0.0097 15.5 0.2 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2688) DUF912 PF06024.7 CDJ66946.1 - 0.016 15.2 0.1 0.053 13.5 0.0 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-LITAF-like PF10601.4 CDJ66946.1 - 0.046 13.5 0.2 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Cortexin PF11057.3 CDJ66946.1 - 0.047 13.2 0.1 0.73 9.4 0.1 2.1 2 0 0 2 2 2 0 Cortexin of kidney TMEM51 PF15345.1 CDJ66946.1 - 0.07 12.8 1.6 0.085 12.5 1.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1517 PF07466.6 CDJ66946.1 - 0.095 11.6 4.5 0.17 10.8 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) SprT-like PF10263.4 CDJ66946.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 SprT-like family E7 PF00527.13 CDJ66946.1 - 0.18 12.0 0.7 0.26 11.4 0.1 1.6 2 0 0 2 2 2 0 E7 protein, Early protein SSP160 PF06933.6 CDJ66946.1 - 5 4.9 10.4 6.5 4.6 7.2 1.3 1 1 0 1 1 1 0 Special lobe-specific silk protein SSP160 F-protein PF00469.15 CDJ66946.1 - 5.2 6.3 5.7 0.33 10.2 0.2 1.6 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Med3 PF11593.3 CDJ66947.1 - 2.3 7.3 8.4 2.1 7.4 5.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.4 CDJ66948.1 - 0.00017 21.1 30.9 0.016 14.6 5.4 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Apt1 PF10351.4 CDJ66948.1 - 0.0064 15.4 2.7 0.0097 14.8 1.8 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Trs65 PF12735.2 CDJ66948.1 - 0.031 13.6 5.5 0.046 13.0 3.8 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF4614 PF15391.1 CDJ66948.1 - 0.033 13.9 17.3 0.28 10.9 6.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Peptidase_M9 PF01752.12 CDJ66948.1 - 0.069 12.0 1.2 0.12 11.2 0.9 1.4 1 0 0 1 1 1 0 Collagenase ETRAMP PF09716.5 CDJ66948.1 - 0.23 11.4 0.1 0.23 11.4 0.0 3.9 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pap_E4 PF02711.9 CDJ66948.1 - 1.6 9.6 7.4 14 6.6 0.1 2.4 2 0 0 2 2 2 0 E4 protein Ctr PF04145.10 CDJ66948.1 - 1.7 8.6 6.4 16 5.4 1.1 2.7 2 0 0 2 2 2 0 Ctr copper transporter family Pex14_N PF04695.8 CDJ66948.1 - 4 7.5 23.3 0.18 11.8 1.0 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pol_alpha_B_N PF08418.5 CDJ66948.1 - 5.4 6.4 13.8 4.8 6.6 0.3 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal PMSR PF01625.16 CDJ66949.1 - 4.1e-46 156.7 0.0 5e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bac_GDH PF05088.7 CDJ66950.1 - 0.22 8.8 14.2 0.31 8.3 9.8 1.2 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase CoA_binding_3 PF13727.1 CDJ66950.1 - 5.3 6.8 14.7 0.33 10.7 4.9 2.6 3 1 0 3 3 3 0 CoA-binding domain Band_3_cyto PF07565.8 CDJ66951.1 - 0.00054 19.5 0.5 0.00054 19.5 0.4 2.4 1 1 1 2 2 2 1 Band 3 cytoplasmic domain DUF3306 PF11748.3 CDJ66951.1 - 3.8 8.1 38.1 1.7 9.3 6.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Allexi_40kDa PF05549.6 CDJ66952.1 - 0.0024 17.2 6.4 0.0032 16.8 4.5 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein Sporozoite_P67 PF05642.6 CDJ66952.1 - 0.069 11.0 6.6 0.083 10.7 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAT1 PF09770.4 CDJ66952.1 - 0.089 11.0 35.3 0.11 10.7 24.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC73 PF05179.9 CDJ66952.1 - 0.1 11.9 8.5 0.15 11.4 5.9 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family DUF4131 PF13567.1 CDJ66952.1 - 0.71 9.2 28.0 0.19 11.1 0.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2217 PF10265.4 CDJ66952.1 - 1.7 7.3 14.6 0.41 9.3 8.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PA26 PF04636.8 CDJ66952.1 - 3.8 6.1 8.4 2.3 6.8 4.9 1.3 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) Med15 PF09606.5 CDJ66953.1 - 1 7.4 97.4 1.6 6.8 67.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4614 PF15391.1 CDJ66956.1 - 3.5 7.3 23.3 1.4 8.6 7.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) TFIIA PF03153.8 CDJ66956.1 - 7.1 6.4 17.4 0.84 9.4 2.0 2.5 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L28e PF01778.12 CDJ66957.1 - 4.3e-20 72.2 0.2 5e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family rve PF00665.21 CDJ66959.1 - 9.3e-17 61.2 0.3 2.7e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDJ66959.1 - 6.7e-09 35.2 0.0 1.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 CDJ66959.1 - 0.0066 15.9 0.0 0.046 13.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain CDC45 PF02724.9 CDJ66960.1 - 0.26 9.2 4.5 0.29 9.1 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PGA_cap PF09587.5 CDJ66960.1 - 0.33 10.2 2.2 0.38 10.0 1.5 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Sox_C_TAD PF12067.3 CDJ66960.1 - 0.62 10.2 17.9 0.92 9.6 12.4 1.3 1 0 0 1 1 1 0 Sox C-terminal transactivation domain FCP1_C PF09309.5 CDJ66960.1 - 2.1 7.5 20.7 0.088 12.1 3.3 2.2 2 0 0 2 2 2 0 FCP1, C-terminal Presenilin PF01080.12 CDJ66960.1 - 2.7 6.6 6.0 3.2 6.4 4.2 1.2 1 0 0 1 1 1 0 Presenilin FimP PF09766.4 CDJ66960.1 - 3.5 6.5 22.7 0.84 8.6 8.7 2.0 2 0 0 2 2 2 0 Fms-interacting protein Helicase_RecD PF05127.9 CDJ66960.1 - 5.5 6.5 7.4 7.1 6.2 5.1 1.3 1 1 0 1 1 1 0 Helicase DUF4551 PF15087.1 CDJ66960.1 - 7.2 4.8 10.8 8.3 4.6 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BAF1_ABF1 PF04684.8 CDJ66961.1 - 0.0014 17.5 17.6 0.0014 17.5 12.2 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDJ66961.1 - 0.01 16.0 16.3 0.013 15.7 11.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Herpes_gE PF02480.11 CDJ66961.1 - 0.025 12.8 0.7 0.029 12.6 0.5 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Bul1_N PF04425.7 CDJ66961.1 - 0.03 12.8 1.9 0.033 12.7 1.3 1.1 1 0 0 1 1 1 0 Bul1 N terminus Activator_LAG-3 PF11498.3 CDJ66961.1 - 0.038 12.7 16.5 0.037 12.7 11.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FimP PF09766.4 CDJ66961.1 - 0.041 12.9 7.5 0.043 12.8 5.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein Mitofilin PF09731.4 CDJ66961.1 - 0.091 11.3 13.6 0.11 11.1 9.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4355 PF14265.1 CDJ66961.1 - 0.1 12.5 9.0 0.13 12.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF4175 PF13779.1 CDJ66961.1 - 0.1 10.2 16.2 0.11 10.2 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDK5_activator PF03261.10 CDJ66961.1 - 0.14 11.4 7.5 0.14 11.4 5.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DMAP_binding PF06464.6 CDJ66961.1 - 0.14 12.7 6.2 0.19 12.3 4.3 1.2 1 0 0 1 1 1 0 DMAP1-binding Domain Med15 PF09606.5 CDJ66961.1 - 0.17 10.0 22.0 0.18 9.9 15.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S30 PF01577.11 CDJ66961.1 - 0.33 10.3 8.5 0.36 10.1 5.9 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease Suf PF05843.9 CDJ66961.1 - 0.35 10.5 6.2 0.35 10.5 4.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2201_N PF13203.1 CDJ66961.1 - 0.39 9.8 11.4 0.43 9.7 7.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain TFIIA PF03153.8 CDJ66961.1 - 0.5 10.2 15.9 0.54 10.0 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4557 PF15101.1 CDJ66961.1 - 0.57 9.9 14.0 0.66 9.7 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) NABP PF07990.7 CDJ66961.1 - 0.62 9.2 8.8 0.73 9.0 6.1 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP FAM117 PF15388.1 CDJ66961.1 - 0.63 9.2 9.5 0.71 9.0 6.6 1.1 1 0 0 1 1 1 0 Protein Family FAM117 DUF3121 PF11319.3 CDJ66961.1 - 0.64 9.4 8.0 0.77 9.2 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) Band_3_cyto PF07565.8 CDJ66961.1 - 0.72 9.3 5.3 0.75 9.2 3.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Glyco_transf_15 PF01793.11 CDJ66961.1 - 0.74 8.7 4.8 0.83 8.5 3.3 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase HGTP_anticodon2 PF12745.2 CDJ66961.1 - 1.1 8.3 6.2 1.3 8.1 4.3 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF966 PF06136.8 CDJ66961.1 - 1.3 8.3 8.8 1.5 8.2 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) UPF0560 PF10577.4 CDJ66961.1 - 1.5 7.0 8.7 1.5 6.9 6.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.2 CDJ66961.1 - 1.6 6.2 7.7 1.7 6.2 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MAP65_ASE1 PF03999.7 CDJ66961.1 - 1.7 7.1 9.3 1.9 7.0 6.4 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) eIF-3_zeta PF05091.7 CDJ66961.1 - 2.1 6.8 10.3 2.1 6.8 7.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AUX_IAA PF02309.11 CDJ66961.1 - 4.1 7.0 7.9 4.5 6.9 5.4 1.1 1 0 0 1 1 1 0 AUX/IAA family E_Pc_C PF06752.7 CDJ66961.1 - 6.5 6.1 22.5 9.5 5.6 15.6 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus SHR3_chaperone PF08229.6 CDJ66961.1 - 8.4 5.2 9.3 12 4.7 6.5 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Presenilin PF01080.12 CDJ66961.1 - 9.4 4.9 6.2 9.3 4.9 4.3 1.1 1 0 0 1 1 1 0 Presenilin HAT PF02184.11 CDJ66962.1 - 0.028 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat TMEM52 PF14979.1 CDJ66963.1 - 0.037 13.9 0.1 0.04 13.8 0.0 1.0 1 0 0 1 1 1 0 Transmembrane 52 Ribosomal_60s PF00428.14 CDJ66963.1 - 0.24 11.8 7.1 0.37 11.2 4.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein EST1 PF10374.4 CDJ66964.1 - 5.8 6.9 8.0 64 3.5 5.5 2.4 1 1 0 1 1 1 0 Telomerase activating protein Est1 DUF3357 PF11837.3 CDJ66968.1 - 0.026 14.3 0.4 0.16 11.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) HECT PF00632.20 CDJ66969.1 - 9.3e-57 192.5 0.0 1.8e-56 191.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GILT PF03227.11 CDJ66970.1 - 2e-19 69.4 0.1 2e-19 69.4 0.1 1.8 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) XAP5 PF04921.9 CDJ66973.1 - 1.5e-32 113.0 1.1 1.7e-32 112.9 0.8 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator DDRGK PF09756.4 CDJ66974.1 - 0.008 15.5 17.2 0.009 15.4 11.9 1.1 1 0 0 1 1 1 1 DDRGK domain IncA PF04156.9 CDJ66974.1 - 0.024 14.2 20.3 0.028 13.9 14.1 1.2 1 0 0 1 1 1 0 IncA protein Med15 PF09606.5 CDJ66974.1 - 0.026 12.7 41.6 0.027 12.7 28.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3373 PF11853.3 CDJ66974.1 - 0.053 12.0 13.2 0.053 12.0 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) SpoIIIAH PF12685.2 CDJ66974.1 - 0.079 12.4 18.8 0.1 12.0 13.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Cwf_Cwc_15 PF04889.7 CDJ66974.1 - 0.089 12.4 20.1 0.12 12.1 14.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FimP PF09766.4 CDJ66974.1 - 0.11 11.5 27.8 0.14 11.1 19.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein Bud13 PF09736.4 CDJ66974.1 - 0.11 12.7 17.3 0.13 12.5 12.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2217 PF10265.4 CDJ66974.1 - 0.15 10.8 26.1 0.17 10.5 18.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4175 PF13779.1 CDJ66974.1 - 0.2 9.2 39.6 0.22 9.1 27.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ADP_ribosyl_GH PF03747.9 CDJ66974.1 - 0.25 11.1 5.9 0.25 11.0 4.1 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase eIF-3_zeta PF05091.7 CDJ66974.1 - 0.29 9.7 21.5 0.31 9.6 14.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.15 CDJ66974.1 - 0.38 9.0 9.9 0.43 8.8 6.9 1.1 1 0 0 1 1 1 0 FHIPEP family eIF3_subunit PF08597.5 CDJ66974.1 - 0.39 10.2 18.7 0.38 10.2 13.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3450 PF11932.3 CDJ66974.1 - 0.51 9.5 31.5 0.54 9.4 21.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PAT1 PF09770.4 CDJ66974.1 - 0.56 8.3 35.5 0.6 8.2 24.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2782 PF11191.3 CDJ66974.1 - 0.58 10.1 9.6 1.1 9.3 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) DUF2681 PF10883.3 CDJ66974.1 - 0.82 9.9 22.5 1.4 9.1 15.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4355 PF14265.1 CDJ66974.1 - 0.85 9.5 23.6 1.1 9.2 16.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Plasmodium_Vir PF05795.6 CDJ66974.1 - 0.95 8.6 12.4 1.3 8.1 8.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4259 PF14078.1 CDJ66974.1 - 1.1 9.7 7.7 1.6 9.2 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) CoA_transf_3 PF02515.12 CDJ66974.1 - 1.2 8.3 9.4 1.3 8.2 6.5 1.1 1 0 0 1 1 1 0 CoA-transferase family III DUF2052 PF09747.4 CDJ66974.1 - 1.2 9.0 21.1 1.4 8.7 14.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Gag_spuma PF03276.9 CDJ66974.1 - 1.3 7.2 35.3 1.5 7.0 24.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein FLO_LFY PF01698.11 CDJ66974.1 - 1.4 7.7 19.0 1.4 7.6 13.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3584 PF12128.3 CDJ66974.1 - 1.6 5.9 27.5 1.5 6.0 19.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ribosomal_60s PF00428.14 CDJ66974.1 - 1.7 9.0 15.0 2.6 8.5 10.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ycf1 PF05758.7 CDJ66974.1 - 1.8 6.2 15.7 1.8 6.2 10.9 1.0 1 0 0 1 1 1 0 Ycf1 Peptidase_S49_N PF08496.5 CDJ66974.1 - 1.9 8.2 12.0 2.8 7.7 8.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BTV_NS2 PF04514.7 CDJ66974.1 - 1.9 7.2 14.3 2 7.2 9.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dicty_REP PF05086.7 CDJ66974.1 - 2.1 5.9 20.1 2.4 5.8 13.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Vfa1 PF08432.5 CDJ66974.1 - 2.2 8.2 20.0 2.7 7.9 13.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 APG6 PF04111.7 CDJ66974.1 - 2.2 7.2 17.6 2.5 7.0 12.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Asp-B-Hydro_N PF05279.6 CDJ66974.1 - 2.3 8.0 10.7 2.2 8.0 7.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GBP_C PF02841.9 CDJ66974.1 - 2.3 7.3 24.9 2.5 7.1 17.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Glyco_transf_15 PF01793.11 CDJ66974.1 - 2.6 6.8 14.1 2.9 6.7 9.7 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Sec62 PF03839.11 CDJ66974.1 - 3.1 7.1 8.1 3.2 7.0 5.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 GvpL_GvpF PF06386.6 CDJ66974.1 - 3.1 7.3 14.8 3.6 7.1 10.3 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Tim54 PF11711.3 CDJ66974.1 - 3.3 6.2 12.1 3.4 6.1 8.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4407 PF14362.1 CDJ66974.1 - 3.4 6.5 22.3 4 6.3 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MRP-S31 PF15433.1 CDJ66974.1 - 3.5 6.9 20.4 4.5 6.5 14.1 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FAM60A PF15396.1 CDJ66974.1 - 3.8 7.1 22.8 6 6.5 15.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.11 CDJ66974.1 - 4.1 7.2 17.3 4.6 7.0 12.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CD20 PF04103.10 CDJ66974.1 - 5.3 6.9 12.5 55 3.6 8.6 2.1 1 1 0 1 1 1 0 CD20-like family Peptidase_S15 PF02129.13 CDJ66974.1 - 5.3 6.3 13.5 6 6.2 9.3 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RskA PF10099.4 CDJ66974.1 - 6.7 6.4 22.5 12 5.5 15.6 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3439 PF11921.3 CDJ66974.1 - 7.1 6.4 6.6 11 5.8 4.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Dehalogenase PF13486.1 CDJ66974.1 - 7.1 5.9 12.0 8.1 5.7 8.3 1.1 1 0 0 1 1 1 0 Reductive dehalogenase subunit Spc7_N PF15402.1 CDJ66974.1 - 7.1 4.4 36.1 10 3.9 25.0 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Utp14 PF04615.8 CDJ66974.1 - 7.4 4.5 26.6 7.9 4.5 18.4 1.0 1 0 0 1 1 1 0 Utp14 protein PIH1 PF08190.7 CDJ66974.1 - 8.3 5.7 22.8 11 5.3 15.8 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Oleosin PF01277.12 CDJ66974.1 - 8.4 5.9 7.9 13 5.3 5.5 1.5 1 0 0 1 1 1 0 Oleosin vMSA PF00695.14 CDJ66974.1 - 8.5 5.4 10.1 9.8 5.2 7.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PIG-S PF10510.4 CDJ66974.1 - 8.7 4.8 20.7 10 4.6 14.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF3824 PF12868.2 CDJ66974.1 - 9.1 7.2 20.3 18 6.2 14.1 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF572 PF04502.8 CDJ66974.1 - 9.8 5.2 26.1 13 4.9 18.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Acyl_transf_3 PF01757.17 CDJ66975.1 - 0.007 15.2 0.0 0.0078 15.0 0.0 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF2946 PF11162.3 CDJ66975.1 - 0.042 14.0 0.6 0.049 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF3675 PF12428.3 CDJ66975.1 - 0.074 13.3 0.1 0.087 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DDE_Tnp_Tn3 PF01526.12 CDJ66975.1 - 0.08 11.5 0.3 0.087 11.4 0.2 1.0 1 0 0 1 1 1 0 Tn3 transposase DDE domain Prominin PF05478.6 CDJ66975.1 - 0.11 9.9 0.7 0.14 9.6 0.5 1.0 1 0 0 1 1 1 0 Prominin Conotoxin PF02950.12 CDJ66975.1 - 1.3 9.8 4.5 7.5 7.4 0.0 2.1 1 1 1 2 2 2 0 Conotoxin Med3 PF11593.3 CDJ66975.1 - 7.5 5.6 8.6 9.1 5.4 5.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4175 PF13779.1 CDJ66976.1 - 0.27 8.8 31.3 0.35 8.5 21.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDJ66976.1 - 0.35 9.0 31.6 0.47 8.6 21.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDJ66976.1 - 2.4 6.3 40.9 3.5 5.7 28.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 CDJ66976.1 - 4.7 6.0 14.3 7.4 5.4 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2722 PF10846.3 CDJ66977.1 - 0.0012 17.9 7.6 0.18 10.7 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) FCP1_C PF09309.5 CDJ66977.1 - 0.05 12.8 14.5 1.9 7.6 6.3 2.5 2 0 0 2 2 2 0 FCP1, C-terminal FimP PF09766.4 CDJ66977.1 - 0.066 12.2 12.4 0.028 13.4 2.0 2.3 2 0 0 2 2 2 0 Fms-interacting protein Spt20 PF12090.3 CDJ66977.1 - 0.072 12.4 8.7 1.6 8.0 1.4 2.9 3 0 0 3 3 3 0 Spt20 family RLL PF10036.4 CDJ66977.1 - 0.094 12.1 7.5 0.1 12.0 2.7 2.1 2 0 0 2 2 2 0 Putative carnitine deficiency-associated protein DUF3446 PF11928.3 CDJ66977.1 - 0.16 12.2 6.1 0.088 13.0 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Pex14_N PF04695.8 CDJ66977.1 - 0.34 10.9 20.3 0.49 10.4 1.4 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Senescence_reg PF04520.8 CDJ66977.1 - 0.4 11.1 13.2 0.34 11.4 4.9 2.5 3 0 0 3 3 3 0 Senescence regulator Med15 PF09606.5 CDJ66977.1 - 0.85 7.7 44.9 0.044 11.9 25.8 1.9 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.1 CDJ66977.1 - 1.5 8.5 5.1 13 5.4 1.1 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF4518 PF15008.1 CDJ66977.1 - 3.3 6.6 7.1 8.6 5.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) LIM_bind PF01803.11 CDJ66977.1 - 4.9 6.1 10.3 5.8 5.9 0.6 2.3 2 0 0 2 2 2 0 LIM-domain binding protein SR-25 PF10500.4 CDJ66977.1 - 8.4 5.7 28.3 0.062 12.7 4.6 2.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF2321 PF10083.4 CDJ66978.1 - 0.039 13.4 0.1 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2HC_2 PF13913.1 CDJ66978.1 - 0.088 12.5 3.7 0.17 11.5 2.5 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type PRTP PF01366.13 CDJ66978.1 - 0.33 8.8 0.1 0.5 8.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF4483 PF14825.1 CDJ66979.1 - 2.6 7.6 11.8 3.5 7.2 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) AAA_23 PF13476.1 CDJ66979.1 - 3.6 7.8 11.1 5.1 7.3 7.7 1.3 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDJ66980.1 - 0.0019 17.7 28.6 0.0019 17.7 19.8 3.4 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDJ66980.1 - 0.086 11.0 24.7 0.1 10.7 17.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ66980.1 - 3.1 7.1 11.6 0.069 12.4 2.6 1.9 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDJ66980.1 - 3.4 6.6 11.9 0.04 12.9 2.2 1.9 2 0 0 2 2 2 0 Fms-interacting protein FAM60A PF15396.1 CDJ66981.1 - 0.16 11.7 5.5 0.17 11.6 3.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Suf PF05843.9 CDJ66981.1 - 1.1 8.8 6.7 1.2 8.8 4.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ66981.1 - 1.4 7.0 20.9 1.6 6.8 14.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AIF_C PF14721.1 CDJ66981.1 - 6.8 6.9 7.6 8.8 6.5 5.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DHHW PF14286.1 CDJ66981.1 - 8.5 5.5 7.1 9.1 5.4 5.0 1.0 1 0 0 1 1 1 0 DHHW protein TFIIA PF03153.8 CDJ66981.1 - 9.3 6.0 17.6 11 5.8 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NIF PF03031.13 CDJ66982.1 - 5.4e-19 68.4 3.8 1.1e-17 64.1 0.2 2.9 2 1 1 3 3 3 2 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CDJ66982.1 - 0.81 9.8 0.0 0.81 9.8 0.0 2.8 1 1 2 3 3 3 0 Haloacid dehalogenase-like hydrolase PCIF1_WW PF12237.3 CDJ66985.1 - 3e-24 85.2 8.6 8.8e-24 83.7 1.6 4.0 2 1 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain SPX PF03105.14 CDJ66985.1 - 4.6e-05 23.3 0.9 4.6e-05 23.3 0.6 5.6 4 2 0 5 5 5 3 SPX domain SR-25 PF10500.4 CDJ66985.1 - 0.00034 20.1 8.8 0.00034 20.1 6.1 7.3 7 0 0 7 7 7 3 Nuclear RNA-splicing-associated protein MRP-S31 PF15433.1 CDJ66985.1 - 0.018 14.4 0.2 0.018 14.4 0.2 5.9 7 0 0 7 7 7 0 Mitochondrial 28S ribosomal protein S31 SR-25 PF10500.4 CDJ66986.1 - 0.0087 15.5 23.6 0.0097 15.3 16.3 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SbcCD_C PF13558.1 CDJ66986.1 - 7.7 6.5 9.5 9.8 6.1 6.3 1.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNase_H2-Ydr279 PF09468.5 CDJ66986.1 - 9.9 5.2 12.2 11 5.1 8.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SPX PF03105.14 CDJ66986.1 - 10 5.8 22.6 11 5.6 15.7 1.0 1 0 0 1 1 1 0 SPX domain Peptidase_S66 PF02016.10 CDJ66988.1 - 0.0097 14.8 0.3 0.011 14.6 0.2 1.0 1 0 0 1 1 1 1 LD-carboxypeptidase Kelch_1 PF01344.20 CDJ66989.1 - 9e-22 76.3 0.0 8.4e-10 38.0 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CDJ66989.1 - 9.7e-22 76.1 0.1 1e-09 38.1 0.0 2.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CDJ66989.1 - 9.6e-20 70.0 0.5 3.1e-09 36.4 0.0 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CDJ66989.1 - 1.7e-14 53.4 0.1 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ66989.1 - 3.2e-06 26.9 0.4 0.19 11.7 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CDJ66989.1 - 4.6e-06 26.1 0.1 0.033 13.9 0.0 3.1 3 1 0 3 3 3 2 Kelch motif DUF1668 PF07893.8 CDJ66989.1 - 0.078 12.0 0.0 0.11 11.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1668) FAD_binding_6 PF00970.19 CDJ66990.1 - 1.7e-06 28.0 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SR-25 PF10500.4 CDJ66990.1 - 0.0014 18.1 11.0 0.0018 17.8 7.6 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Myco_19_kDa PF05481.7 CDJ66990.1 - 0.039 13.7 1.5 0.045 13.5 1.1 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen SoxE PF06525.6 CDJ66990.1 - 0.041 13.1 0.4 0.048 12.9 0.3 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) P12 PF12669.2 CDJ66990.1 - 0.11 12.6 0.1 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF3446 PF11928.3 CDJ66990.1 - 0.18 12.0 7.0 0.24 11.6 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF755 PF05501.6 CDJ66990.1 - 1.6 8.7 13.6 2.7 8.0 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) WD40 PF00400.27 CDJ66991.1 - 0.00046 19.9 0.0 0.00046 19.9 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Ribosomal_60s PF00428.14 CDJ66991.1 - 0.00067 20.0 26.5 0.072 13.5 9.4 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein RuBisCO_large_N PF02788.11 CDJ66991.1 - 0.019 14.6 1.8 0.019 14.6 1.3 2.6 1 1 1 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain DUF4367 PF14285.1 CDJ66991.1 - 0.34 10.2 6.8 1.7 7.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) DUF536 PF04394.9 CDJ66991.1 - 0.53 10.0 13.7 0.86 9.3 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF536 PsbQ PF05757.6 CDJ66991.1 - 0.78 9.1 12.6 1.4 8.2 0.9 2.2 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) RAP1 PF07218.6 CDJ66991.1 - 1.5 6.8 6.3 11 3.8 3.6 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF2057 PF09829.4 CDJ66991.1 - 4.1 7.0 9.1 1.3 8.6 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Transposase_24 PF03004.9 CDJ66992.1 - 0.13 12.1 1.2 0.14 12.0 0.9 1.2 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) COX6A PF02046.10 CDJ66992.1 - 1.9 8.4 4.8 2.6 7.9 3.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa Peptidase_S64 PF08192.6 CDJ66992.1 - 6.8 4.8 6.5 7.4 4.7 4.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3984 PF13136.1 CDJ66992.1 - 8.9 5.4 10.0 9.9 5.2 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) CAF-1_p150 PF11600.3 CDJ66993.1 - 0.0023 17.3 31.3 0.0032 16.8 21.7 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 CDJ66993.1 - 3.8 7.8 30.4 4.3 7.6 21.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein ATP-synt_C PF00137.16 CDJ66994.1 - 0.0085 15.9 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Suf PF05843.9 CDJ66994.1 - 0.33 10.6 3.4 0.41 10.3 2.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TSA PF03249.8 CDJ66994.1 - 4.3 5.7 8.0 5.1 5.5 5.5 1.1 1 0 0 1 1 1 0 Type specific antigen Med15 PF09606.5 CDJ66995.1 - 0.01 14.0 22.7 0.011 13.9 15.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Paramyxo_ncap PF00973.14 CDJ66995.1 - 1.8 7.1 8.0 2 7.0 5.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1183 PF06682.7 CDJ66996.1 - 0.064 12.8 0.3 0.089 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RAP PF08373.5 CDJ66997.1 - 2.9e-13 49.3 0.0 2.1e-12 46.6 0.0 2.6 1 0 0 1 1 1 1 RAP domain SP2 PF03014.9 CDJ66999.1 - 0.16 9.7 0.3 0.29 8.9 0.2 1.3 1 0 0 1 1 1 0 Structural protein 2 Thiolase_N PF00108.18 CDJ67002.1 - 6.9e-59 198.9 0.0 3.5e-46 157.3 0.0 2.1 2 0 0 2 2 2 2 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 CDJ67002.1 - 0.00014 21.4 7.7 0.0042 16.6 2.1 3.3 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CDJ67002.1 - 0.00041 19.9 7.2 0.03 13.9 0.1 3.1 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Phostensin_N PF13916.1 CDJ67002.1 - 0.11 12.4 3.6 0.3 11.0 2.5 1.7 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal RNA_pol_N PF01194.12 CDJ67003.1 - 0.011 15.6 0.2 2.9 7.9 0.1 2.8 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit Ubiq_cyt_C_chap PF03981.7 CDJ67003.1 - 0.067 13.0 0.7 4.3 7.1 0.0 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone PhnG PF06754.7 CDJ67003.1 - 0.17 11.5 5.7 3.7 7.1 0.4 2.2 1 1 1 2 2 2 0 Phosphonate metabolism protein PhnG DUF3446 PF11928.3 CDJ67003.1 - 0.25 11.5 12.8 0.46 10.7 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Herpes_capsid PF06112.6 CDJ67003.1 - 1.6 8.7 11.4 2.3 8.2 7.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Corona_nucleoca PF00937.13 CDJ67003.1 - 5.1 5.9 8.9 7.1 5.4 6.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3618 PF12277.3 CDJ67003.1 - 6.2 6.9 6.4 22 5.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) SAC3_GANP PF03399.11 CDJ67004.1 - 1.3e-33 116.2 2.9 1.3e-33 116.2 2.0 2.6 3 0 0 3 3 3 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family ELMO_CED12 PF04727.8 CDJ67005.1 - 9.2e-11 41.5 16.4 9.2e-11 41.5 11.4 3.2 2 1 1 3 3 3 2 ELMO/CED-12 family BAF1_ABF1 PF04684.8 CDJ67005.1 - 0.00024 20.1 11.9 0.00024 20.1 8.2 8.3 6 3 4 10 10 10 1 BAF1 / ABF1 chromatin reorganising factor DUF3610 PF12272.3 CDJ67005.1 - 0.0083 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3610) SAGA-Tad1 PF12767.2 CDJ67005.1 - 0.023 14.3 42.1 0.7 9.4 1.4 3.5 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDJ67005.1 - 0.18 10.0 97.8 0.0094 14.2 2.7 3.2 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 CDJ67007.1 - 1 9.6 18.3 1.3 9.3 6.4 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Utp14 PF04615.8 CDJ67010.1 - 0.22 9.6 54.5 0.34 9.0 37.8 1.2 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.4 CDJ67010.1 - 5.5 5.1 136.9 7.8 4.6 94.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Parvo_coat PF00740.13 CDJ67010.1 - 9.2 5.0 54.5 11 4.8 37.8 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DS PF01916.12 CDJ67013.1 - 3.6e-94 315.2 0.0 2e-55 188.0 0.0 2.7 2 1 0 2 2 2 2 Deoxyhypusine synthase Apt1 PF10351.4 CDJ67013.1 - 0.031 13.1 13.9 0.048 12.5 0.9 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SR-25 PF10500.4 CDJ67013.1 - 0.083 12.3 54.4 0.045 13.2 11.1 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.1 CDJ67013.1 - 0.31 10.7 21.0 0.58 9.8 4.5 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Nop25 PF09805.4 CDJ67013.1 - 0.43 10.6 15.3 0.27 11.2 2.8 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Peptidase_M91 PF14891.1 CDJ67013.1 - 1 9.4 6.6 0.59 10.1 2.5 1.9 2 0 0 2 2 2 0 Effector protein CDC45 PF02724.9 CDJ67013.1 - 1.8 6.5 15.7 0.81 7.6 3.1 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF3573 PF12097.3 CDJ67013.1 - 6.2 5.3 12.1 0.13 10.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) TFIIA PF03153.8 CDJ67014.1 - 0.38 10.6 20.2 0.57 10.0 14.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 CDJ67014.1 - 0.73 8.7 12.0 0.11 11.4 0.8 3.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MACPF PF01823.14 CDJ67014.1 - 2 8.0 12.8 16 5.1 0.0 2.5 3 0 0 3 3 3 0 MAC/Perforin domain YajC PF02699.10 CDJ67014.1 - 3.5 7.3 15.3 5 6.8 0.5 3.2 3 0 0 3 3 3 0 Preprotein translocase subunit Pex14_N PF04695.8 CDJ67015.1 - 0.042 13.9 6.9 0.037 14.0 0.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.4 CDJ67015.1 - 0.58 9.6 16.9 0.019 14.4 7.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ago_hook PF10427.4 CDJ67015.1 - 9.8 6.2 17.7 0.59 10.1 4.2 2.4 2 0 0 2 2 2 0 Argonaute hook Proteasome PF00227.21 CDJ67016.1 - 5.7e-59 198.6 0.0 7e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDJ67016.1 - 1.6e-14 52.9 0.4 2.5e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GM_CSF PF01109.12 CDJ67016.1 - 0.019 14.9 0.2 0.041 13.8 0.0 1.6 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor DSPc PF00782.15 CDJ67017.1 - 1.7e-25 89.1 0.0 2.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDJ67017.1 - 0.00045 19.6 0.0 0.00067 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CDJ67017.1 - 0.0017 18.4 0.1 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Ribosomal_L36 PF00444.13 CDJ67017.1 - 0.043 13.8 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Ribosomal protein L36 Cpn10 PF00166.16 CDJ67018.1 - 0.81 9.6 15.8 1.3 8.9 0.6 3.9 2 1 1 3 3 3 0 Chaperonin 10 Kd subunit Sec1 PF00995.18 CDJ67019.1 - 4.4e-19 68.5 0.0 5.2e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 CDJ67020.1 - 1.9e-80 271.1 1.2 2.3e-80 270.8 0.8 1.0 1 0 0 1 1 1 1 Sec1 family YlbD_coat PF14071.1 CDJ67020.1 - 0.0044 17.0 0.5 0.054 13.5 0.3 2.2 2 0 0 2 2 2 1 Putative coat protein SEO_C PF14577.1 CDJ67020.1 - 0.018 14.4 0.3 0.027 13.8 0.2 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Dor1 PF04124.7 CDJ67021.1 - 9.6e-25 86.7 1.1 1.4e-24 86.1 0.8 1.2 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.6 CDJ67021.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Vps51/Vps67 PK PF00224.16 CDJ67022.1 - 1.1e-144 481.3 0.7 1.5e-144 480.9 0.5 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CDJ67022.1 - 1.1e-32 112.0 1.2 5.1e-32 109.8 0.6 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CDJ67022.1 - 0.00055 18.8 0.7 0.0013 17.6 0.1 1.9 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Vps8 PF12816.2 CDJ67022.1 - 0.13 11.5 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Adap_comp_sub PF00928.16 CDJ67023.1 - 1.4e-08 34.1 0.0 2.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CDJ67023.1 - 0.15 11.7 0.3 0.58 9.8 0.1 2.0 2 0 0 2 2 2 0 Clathrin adaptor complex small chain IncA PF04156.9 CDJ67024.1 - 3.1 7.3 25.4 9.5 5.7 17.6 1.8 1 1 0 1 1 1 0 IncA protein Filament PF00038.16 CDJ67024.1 - 4 6.7 20.9 1.2 8.5 11.5 1.9 1 1 1 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 CDJ67024.1 - 5.2 5.4 9.1 7.8 4.8 6.3 1.3 1 0 0 1 1 1 0 AAA domain Pox_A14 PF05767.7 CDJ67025.1 - 0.03 14.2 1.8 0.03 14.2 1.3 2.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 TctA PF01970.11 CDJ67025.1 - 0.46 8.8 7.6 0.018 13.4 1.4 1.4 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family dCMP_cyt_deam_1 PF00383.17 CDJ67027.1 - 1.8e-06 27.5 2.2 2.4e-06 27.1 0.4 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF605 PF04652.11 CDJ67027.1 - 0.0061 16.0 29.7 0.0079 15.6 20.6 1.3 1 0 0 1 1 1 1 Vta1 like Med15 PF09606.5 CDJ67027.1 - 0.0073 14.5 55.9 0.0087 14.3 38.7 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Virul_Fac PF10139.4 CDJ67027.1 - 0.011 13.7 11.0 0.014 13.3 7.6 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor TFIIA PF03153.8 CDJ67027.1 - 0.017 15.0 35.8 0.02 14.8 24.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ67027.1 - 0.043 12.0 57.2 0.054 11.7 39.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ67027.1 - 0.13 12.5 9.7 0.18 12.1 6.7 1.2 1 0 0 1 1 1 0 AAA domain DUF2201_N PF13203.1 CDJ67027.1 - 0.42 9.7 18.7 0.58 9.2 12.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 CDJ67027.1 - 0.48 10.2 16.7 0.87 9.4 11.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.6 CDJ67027.1 - 0.48 9.9 11.0 0.71 9.3 7.6 1.3 1 0 0 1 1 1 0 PPP4R2 Plasmodium_Vir PF05795.6 CDJ67027.1 - 1.2 8.2 4.3 1.7 7.7 3.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.2 CDJ67027.1 - 2.1 5.9 18.0 2.5 5.6 12.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDJ67027.1 - 2.4 5.7 11.3 2.4 5.7 7.8 1.1 1 0 0 1 1 1 0 Ycf1 XAP5 PF04921.9 CDJ67027.1 - 3 7.3 8.7 4.1 6.9 6.1 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Pox_Ag35 PF03286.9 CDJ67027.1 - 3.1 7.2 10.4 4.9 6.6 7.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AvrE PF11725.3 CDJ67027.1 - 4 4.3 19.5 4.3 4.2 13.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor SAPS PF04499.10 CDJ67027.1 - 4.3 5.8 10.9 5.2 5.5 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 CDJ67027.1 - 6.2 4.9 17.1 7.4 4.7 11.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDK5_activator PF03261.10 CDJ67027.1 - 6.8 5.9 18.5 8.4 5.6 12.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CDC45 PF02724.9 CDJ67027.1 - 6.8 4.5 12.7 8.3 4.3 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.1 CDJ67027.1 - 8 4.6 17.4 10 4.3 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RRM_1 PF00076.17 CDJ67029.1 - 6.3e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ67029.1 - 0.0078 16.1 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ67029.1 - 0.022 14.5 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 CDJ67029.1 - 0.36 8.9 28.4 0.39 8.8 19.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDJ67029.1 - 0.82 8.3 27.8 1 8.0 19.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAT1 PF09770.4 CDJ67029.1 - 2.7 6.1 22.7 3.2 5.8 15.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-B_box PF00643.19 CDJ67031.1 - 0.0004 20.2 6.5 0.0004 20.2 4.5 1.8 2 0 0 2 2 2 1 B-box zinc finger DUF3584 PF12128.3 CDJ67031.1 - 0.057 10.7 0.8 0.069 10.4 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4367 PF14285.1 CDJ67032.1 - 0.022 14.0 1.0 0.023 14.0 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) AA_permease_N PF08403.5 CDJ67032.1 - 0.038 13.3 0.4 0.052 12.8 0.3 1.2 1 0 0 1 1 1 0 Amino acid permease N-terminal FPN1 PF06963.7 CDJ67032.1 - 0.049 12.0 1.3 0.05 11.9 0.9 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Herpes_glycop PF01528.11 CDJ67032.1 - 0.19 10.3 0.7 0.18 10.4 0.5 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Shadoo PF14999.1 CDJ67032.1 - 0.33 10.8 10.9 0.35 10.7 7.5 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF2390 PF09523.5 CDJ67032.1 - 0.45 10.7 12.2 0.47 10.6 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) MelC1 PF06236.6 CDJ67032.1 - 1.3 9.0 11.2 1.5 8.7 7.8 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 ADP_PFK_GK PF04587.10 CDJ67032.1 - 1.3 7.1 6.6 1.4 7.0 4.6 1.0 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Med15 PF09606.5 CDJ67032.1 - 1.8 6.6 25.4 1.8 6.6 17.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDJ67032.1 - 1.8 8.2 15.5 2.6 7.7 10.7 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Activator_LAG-3 PF11498.3 CDJ67032.1 - 1.9 7.1 20.4 2 7.0 14.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Wzz PF02706.10 CDJ67032.1 - 2.3 8.0 7.8 2.8 7.7 5.4 1.1 1 0 0 1 1 1 0 Chain length determinant protein Gastrin PF00918.12 CDJ67032.1 - 3.3 8.5 13.8 3.6 8.4 9.6 1.0 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF2681 PF10883.3 CDJ67032.1 - 3.4 7.9 13.9 4 7.7 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Macoilin PF09726.4 CDJ67032.1 - 4.6 5.3 10.5 4.6 5.4 7.3 1.0 1 0 0 1 1 1 0 Transmembrane protein R_equi_Vir PF05526.6 CDJ67032.1 - 4.9 6.7 8.7 5.4 6.6 6.0 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2782 PF11191.3 CDJ67032.1 - 5.9 6.9 7.7 8.1 6.4 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) DUF1845 PF08900.6 CDJ67033.1 - 0.0048 16.2 1.1 0.006 15.8 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1845) ZYG-11_interact PF05884.7 CDJ67033.1 - 0.035 13.2 0.6 0.036 13.1 0.4 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF4457 PF14652.1 CDJ67033.1 - 0.05 12.5 0.2 0.064 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) HTH_Tnp_IS630 PF01710.11 CDJ67033.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Transposase Dala_Dala_lig_N PF01820.16 CDJ67033.1 - 0.11 12.7 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Phostensin_N PF13916.1 CDJ67033.1 - 0.16 12.0 2.6 0.31 11.0 1.8 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal FlgM PF04316.8 CDJ67033.1 - 1.6 8.6 8.8 0.25 11.3 3.3 1.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM RNA_pol_L PF01193.19 CDJ67034.1 - 2.7e-05 23.2 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4131 PF13567.1 CDJ67034.1 - 0.066 12.6 0.9 0.099 12.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Viral_Beta_CD PF04530.7 CDJ67034.1 - 4.9 7.3 7.3 33 4.6 0.0 2.3 2 0 0 2 2 2 0 Viral Beta C/D like family NAP PF00956.13 CDJ67035.1 - 1.8e-05 24.0 0.0 1.8e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) SDA1 PF05285.7 CDJ67035.1 - 0.33 10.2 6.8 0.28 10.4 4.7 1.0 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.5 CDJ67035.1 - 0.49 10.6 11.1 0.6 10.3 7.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.8 CDJ67035.1 - 0.54 9.8 7.2 0.52 9.8 5.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoplasmin PF03066.10 CDJ67035.1 - 6.2 6.3 10.4 8.1 5.9 7.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin Macoilin PF09726.4 CDJ67036.1 - 0.046 12.0 14.7 0.1 10.8 10.2 1.6 1 0 0 1 1 1 0 Transmembrane protein zf-CCHC PF00098.18 CDJ67037.1 - 5.9e-08 32.2 9.0 0.00025 20.8 1.0 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ67037.1 - 0.0024 17.5 2.3 0.082 12.6 0.1 2.4 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDJ67037.1 - 0.0031 16.9 6.8 0.14 11.6 0.2 3.2 3 0 0 3 3 3 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ67037.1 - 0.0084 16.1 4.3 0.018 15.1 3.0 1.4 1 0 0 1 1 1 1 DnaJ central domain zf-CCHC_5 PF14787.1 CDJ67037.1 - 0.012 15.0 1.4 0.012 15.0 1.0 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Retrotrans_gag PF03732.12 CDJ67037.1 - 0.11 12.5 0.2 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC_4 PF14392.1 CDJ67037.1 - 0.36 10.5 6.8 1.9 8.1 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 CDJ67037.1 - 0.76 9.6 5.9 7.5 6.4 0.6 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Kringle PF00051.13 CDJ67038.1 - 1e-10 41.5 1.6 2e-10 40.5 1.1 1.5 1 0 0 1 1 1 1 Kringle domain BAF1_ABF1 PF04684.8 CDJ67039.1 - 0.0044 15.9 17.1 0.0057 15.5 11.9 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF3138 PF11336.3 CDJ67039.1 - 0.13 10.3 12.4 0.16 10.0 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CDK2AP PF09806.4 CDJ67039.1 - 0.67 10.1 10.6 0.84 9.8 7.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PerC PF06069.6 CDJ67040.1 - 0.035 14.1 0.8 0.061 13.3 0.6 1.4 1 0 0 1 1 1 0 PerC transcriptional activator Dpy-30 PF05186.8 CDJ67041.1 - 0.16 11.4 7.0 0.19 11.2 0.1 2.7 3 0 0 3 3 3 0 Dpy-30 motif AAA_23 PF13476.1 CDJ67043.1 - 1.2 9.3 22.9 1.8e+03 -1.0 15.8 2.4 1 1 0 1 1 1 0 AAA domain Proteasome PF00227.21 CDJ67044.1 - 8.9e-50 168.6 0.0 1.1e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_60s PF00428.14 CDJ67044.1 - 1.9 8.9 8.8 5.1 7.5 0.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-met PF12874.2 CDJ67045.1 - 0.0001 22.3 1.8 0.00019 21.5 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CDJ67045.1 - 0.00012 22.1 1.2 0.00023 21.2 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 CDJ67045.1 - 0.23 11.0 0.9 0.52 9.9 0.6 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF4179 PF13786.1 CDJ67045.1 - 0.56 10.4 2.9 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Mcm10 PF09332.6 CDJ67047.1 - 0.0026 17.1 21.5 0.0026 17.1 14.9 3.1 2 1 1 3 3 3 1 Mcm10 replication factor Pescadillo_N PF06732.6 CDJ67047.1 - 3.9 6.6 9.4 0.076 12.2 0.5 2.4 2 1 1 3 3 3 0 Pescadillo N-terminus WD40 PF00400.27 CDJ67048.1 - 6.4e-05 22.6 1.2 0.00041 20.1 0.0 2.4 2 1 0 2 2 2 1 WD domain, G-beta repeat Ribosomal_60s PF00428.14 CDJ67048.1 - 0.056 13.8 17.0 0.096 13.0 5.3 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein BBS2_N PF14781.1 CDJ67048.1 - 0.062 12.9 0.8 0.88 9.1 0.1 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal APC_CDC26 PF10471.4 CDJ67048.1 - 0.086 13.5 5.5 1.6 9.4 0.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 ERCC4 PF02732.10 CDJ67048.1 - 0.31 10.7 1.7 0.29 10.8 0.4 1.5 2 0 0 2 2 2 0 ERCC4 domain YajC PF02699.10 CDJ67048.1 - 0.73 9.5 4.7 9.3 6.0 0.4 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit Cytadhesin_P30 PF07271.6 CDJ67048.1 - 0.81 8.9 8.6 1.1 8.4 5.9 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 TFIIA PF03153.8 CDJ67048.1 - 1.4 8.7 8.5 1.9 8.3 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Surface_antigen PF11054.3 CDJ67049.1 - 7.3e-11 41.9 0.2 1.2e-10 41.2 0.0 1.4 2 0 0 2 2 2 1 Sporozoite TA4 surface antigen Lantibiotic_a PF14867.1 CDJ67049.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lantibiotic alpha rve PF00665.21 CDJ67050.1 - 1.9e-17 63.4 0.0 4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CDJ67050.1 - 8.1e-12 45.4 0.0 2.2e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CDJ67050.1 - 2.5e-09 36.7 0.0 5.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CDJ67050.1 - 1.6e-07 31.0 0.0 4.7e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ67050.1 - 5.2e-07 29.5 0.0 1.6e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ67050.1 - 8.9e-07 28.9 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ67050.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Rad50_zn_hook PF04423.9 CDJ67051.1 - 0.74 9.3 3.4 1.6 8.2 2.4 1.6 1 1 0 1 1 1 0 Rad50 zinc hook motif DUF3313 PF11769.3 CDJ67051.1 - 0.79 9.0 6.6 0.77 9.0 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) DinI PF06183.8 CDJ67051.1 - 3.3 7.7 6.8 35 4.5 4.7 2.0 1 1 0 1 1 1 0 DinI-like family DUF2939 PF11159.3 CDJ67051.1 - 9.1 6.5 6.6 9 6.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Ldh_1_N PF00056.18 CDJ67052.1 - 1.8e-37 128.3 0.2 2.1e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 CDJ67052.1 - 1.7e-06 27.5 1.0 0.00011 21.6 0.1 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.14 CDJ67052.1 - 0.021 13.5 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CDJ67052.1 - 0.037 14.4 4.2 0.27 11.6 1.2 2.6 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent B12-binding PF02310.14 CDJ67052.1 - 0.053 13.3 0.3 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 B12 binding domain ACT_5 PF13710.1 CDJ67053.1 - 0.033 13.9 0.2 0.07 12.9 0.1 1.4 1 0 0 1 1 1 0 ACT domain Med3 PF11593.3 CDJ67053.1 - 1 8.4 18.3 0.19 10.9 4.3 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal COX6B PF02297.12 CDJ67054.1 - 2.1e-05 24.4 4.6 3.1e-05 23.9 3.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UTRA PF07702.8 CDJ67054.1 - 0.13 11.8 0.1 0.22 11.1 0.0 1.4 2 0 0 2 2 2 0 UTRA domain Trypsin_2 PF13365.1 CDJ67056.1 - 3.5e-14 52.8 0.5 3.5e-14 52.8 0.3 2.2 2 1 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 CDJ67056.1 - 4.7e-12 45.9 0.0 3.6e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Trypsin PDZ_2 PF13180.1 CDJ67056.1 - 0.00042 20.1 0.1 0.52 10.2 0.0 3.3 3 0 0 3 3 3 2 PDZ domain Hid1 PF12722.2 CDJ67056.1 - 5.9 4.4 11.6 61 1.0 8.0 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Med4 PF10018.4 CDJ67057.1 - 6.6e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1176 PF06674.6 CDJ67057.1 - 0.03 13.4 0.1 0.052 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) DUF1604 PF07713.8 CDJ67058.1 - 1.3e-10 40.8 1.1 1.3e-10 40.8 0.7 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1604) Methyltransf_31 PF13847.1 CDJ67059.1 - 2.3e-13 50.0 0.0 8.5e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ67059.1 - 1.5e-12 47.5 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ67059.1 - 5.9e-12 46.1 0.1 8.2e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CDJ67059.1 - 2.6e-10 39.9 0.0 4.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 CDJ67059.1 - 3.3e-09 37.1 0.0 9.7e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDJ67059.1 - 7.7e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CDJ67059.1 - 2.1e-05 24.8 0.1 0.00013 22.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 CDJ67059.1 - 4.8e-05 22.4 0.0 8.2e-05 21.7 0.0 1.3 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 CDJ67059.1 - 0.00011 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CDJ67059.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CDJ67059.1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.6 CDJ67059.1 - 0.0031 16.2 0.0 0.0071 15.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 CDJ67059.1 - 0.0036 16.4 0.0 0.018 14.1 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 CDJ67059.1 - 0.0069 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 CDJ67059.1 - 0.0072 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CDJ67059.1 - 0.009 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 CDJ67059.1 - 0.0096 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AKAP28 PF14469.1 CDJ67059.1 - 0.011 15.3 0.4 8.1 6.0 0.0 3.3 3 0 0 3 3 3 0 28 kDa A-kinase anchor Methyltransf_12 PF08242.7 CDJ67059.1 - 0.027 14.9 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 CDJ67059.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.1 CDJ67059.1 - 0.042 14.6 0.0 0.094 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 CDJ67059.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ras PF00071.17 CDJ67060.1 - 3.1e-60 202.2 0.2 3.7e-60 201.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ67060.1 - 2e-18 67.0 0.0 4.7e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CDJ67060.1 - 7.4e-14 51.3 0.0 9.3e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDJ67060.1 - 3.8e-06 26.2 0.0 4.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CDJ67060.1 - 4.2e-05 23.4 0.0 8.1e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDJ67060.1 - 0.00053 19.4 0.2 0.0016 17.9 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CDJ67060.1 - 0.00058 19.1 0.0 0.0012 18.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CDJ67060.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CDJ67060.1 - 0.024 13.8 0.0 0.046 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDJ67060.1 - 0.046 13.7 1.4 0.19 11.7 1.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Cu_amine_oxid PF01179.15 CDJ67061.1 - 8.5e-70 235.5 0.2 1.6e-69 234.6 0.1 1.3 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.18 CDJ67061.1 - 2e-32 112.1 0.0 3.9e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 MAM domain DUF1965 PF09248.5 CDJ67061.1 - 0.056 13.3 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Fb_signal PF08341.6 CDJ67061.1 - 0.084 12.9 0.0 2.3 8.3 0.0 3.0 3 0 0 3 3 3 0 Fibronectin-binding protein signal sequence DUF3439 PF11921.3 CDJ67063.1 - 9.4 6.0 17.1 1.6 8.5 6.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Phosphonate-bd PF12974.2 CDJ67065.1 - 0.035 13.4 0.1 0.065 12.5 0.1 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Brix PF04427.13 CDJ67068.1 - 8.1e-27 94.1 0.0 2.1e-26 92.7 0.0 1.7 1 1 0 1 1 1 1 Brix domain Ctr PF04145.10 CDJ67070.1 - 0.58 10.2 5.3 7.6 6.5 0.0 3.6 3 0 0 3 3 3 0 Ctr copper transporter family AnfO_nitrog PF09582.5 CDJ67071.1 - 0.062 12.4 0.1 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DnaJ PF00226.26 CDJ67072.1 - 1.6e-12 46.9 1.1 2.6e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain Actino_peptide PF14408.1 CDJ67072.1 - 0.03 14.2 0.2 0.03 14.2 0.1 2.8 3 0 0 3 3 3 0 Ribosomally synthesized peptide in actinomycetes US22 PF02393.11 CDJ67072.1 - 0.04 13.9 0.1 9.3 6.2 0.0 2.9 2 1 1 3 3 3 0 US22 like SNARE_assoc PF09335.6 CDJ67076.1 - 5.2e-09 36.3 7.3 0.00026 21.1 0.0 3.0 3 0 0 3 3 3 2 SNARE associated Golgi protein CDK2AP PF09806.4 CDJ67076.1 - 0.0063 16.7 0.2 0.0082 16.3 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein DUF3752 PF12572.3 CDJ67076.1 - 0.0092 16.1 0.5 0.013 15.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Apt1 PF10351.4 CDJ67076.1 - 0.065 12.0 0.1 0.083 11.7 0.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3154 PF11351.3 CDJ67076.1 - 0.57 9.9 15.1 0.6 9.8 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3154) Chromo PF00385.19 CDJ67078.1 - 1.8e-12 46.7 0.0 5.8e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDJ67078.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain rve PF00665.21 CDJ67079.1 - 1.7e-20 73.3 0.0 6.7e-20 71.3 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDJ67079.1 - 4.4e-15 55.6 0.0 8e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CDJ67079.1 - 9.9e-08 32.3 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ67079.1 - 2.4e-07 30.4 0.1 7.9e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Chromo PF00385.19 CDJ67079.1 - 7.4e-06 25.5 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 CDJ67079.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ67079.1 - 0.021 14.7 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-H2C2 PF09337.5 CDJ67079.1 - 0.025 13.9 0.9 0.052 12.9 0.6 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger DUF1758 PF05585.7 CDJ67079.1 - 0.36 10.3 0.0 0.74 9.3 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DNA_topoisoIV PF00521.15 CDJ67080.1 - 5e-112 374.8 0.0 7.2e-112 374.3 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CDJ67080.1 - 9e-29 99.8 0.3 2.3e-28 98.5 0.2 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CDJ67080.1 - 2.5e-13 49.8 0.0 7.6e-13 48.2 0.0 1.9 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CDJ67080.1 - 1.7e-08 34.1 0.1 5.3e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nucleoporin_FG PF13634.1 CDJ67081.1 - 5.1e-44 149.1 310.8 3e-09 37.1 34.9 9.2 3 2 7 10 10 10 9 Nucleoporin FG repeat region Ribosomal_S27 PF01599.14 CDJ67083.1 - 2.4e-25 88.1 2.7 4.2e-25 87.3 1.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 CDJ67083.1 - 4.3e-12 45.2 0.0 8.4e-12 44.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDJ67083.1 - 1.7e-06 27.6 0.0 5.3e-06 26.0 0.0 1.7 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDJ67083.1 - 0.012 15.8 0.0 0.099 12.9 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain IBR PF01485.16 CDJ67083.1 - 0.015 15.1 1.4 0.023 14.5 1.0 1.4 1 0 0 1 1 1 0 IBR domain Stig1 PF04885.8 CDJ67083.1 - 0.021 15.0 0.6 0.029 14.5 0.4 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Telomere_Sde2 PF13019.1 CDJ67083.1 - 0.072 12.7 0.9 0.089 12.4 0.0 1.6 1 1 1 2 2 2 0 Telomere stability and silencing Cucumo_2B PF03263.8 CDJ67083.1 - 0.084 13.1 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Cucumovirus protein 2B EF_TS PF00889.14 CDJ67084.1 - 2.7e-29 102.0 0.2 4.1e-28 98.2 0.1 2.6 2 1 0 2 2 2 1 Elongation factor TS UBA PF00627.26 CDJ67084.1 - 1.2e-07 31.3 0.6 5.9e-07 29.1 0.1 2.4 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CDJ67084.1 - 0.0016 17.9 0.4 0.027 14.0 0.0 2.4 2 0 0 2 2 2 1 UBA-like domain DrsE PF02635.10 CDJ67084.1 - 0.056 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 DsrE/DsrF-like family SNase PF00565.12 CDJ67086.1 - 2.6e-10 40.5 0.0 0.15 12.3 0.0 4.7 4 1 0 4 4 4 3 Staphylococcal nuclease homologue DUF1292 PF06949.6 CDJ67086.1 - 0.065 13.5 0.3 0.19 12.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) RNA_pol_A_CTD PF03118.10 CDJ67086.1 - 0.12 11.8 0.5 0.24 10.8 0.4 1.4 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Ino80_Iec3 PF14612.1 CDJ67087.1 - 0.012 15.7 0.9 0.019 15.0 0.6 1.2 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Pap_E4 PF02711.9 CDJ67087.1 - 0.14 12.9 2.9 0.35 11.7 1.9 1.7 2 0 0 2 2 2 0 E4 protein zf-C2HC_2 PF13913.1 CDJ67088.1 - 5e-07 29.2 7.0 5e-07 29.2 4.9 1.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Med15 PF09606.5 CDJ67089.1 - 0.001 17.3 0.2 0.001 17.3 0.1 2.5 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1183 PF06682.7 CDJ67089.1 - 0.045 13.3 9.8 0.66 9.5 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Mito_carr PF00153.22 CDJ67089.1 - 0.093 12.4 0.0 0.093 12.4 0.0 6.8 4 3 2 7 7 7 0 Mitochondrial carrier protein Kinesin PF00225.18 CDJ67090.1 - 3.4e-42 144.3 0.0 3.4e-42 144.3 0.0 3.4 3 0 0 3 3 3 1 Kinesin motor domain FHA PF00498.21 CDJ67090.1 - 7.3e-08 32.4 0.0 2.3e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 FHA domain SRP_SPB PF02978.14 CDJ67091.1 - 0.017 15.4 0.4 0.051 13.8 0.0 2.0 2 0 0 2 2 2 0 Signal peptide binding domain DUF1679 PF07914.6 CDJ67091.1 - 0.13 10.8 0.2 0.2 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APC_CDC26 PF10471.4 CDJ67095.1 - 0.33 11.7 6.4 0.46 11.2 4.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 MLANA PF14991.1 CDJ67095.1 - 0.41 10.6 2.1 0.55 10.2 1.5 1.2 1 0 0 1 1 1 0 Protein melan-A UPF0560 PF10577.4 CDJ67095.1 - 0.45 8.7 7.4 0.52 8.5 5.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Med15 PF09606.5 CDJ67095.1 - 0.63 8.1 12.6 0.68 8.0 8.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDJ67095.1 - 0.75 8.5 10.9 1.1 8.0 7.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDJ67095.1 - 4.6 7.4 9.4 6.1 7.0 6.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Radial_spoke PF04712.7 CDJ67097.1 - 1.7e-61 208.5 0.1 3.4e-36 125.0 0.1 3.2 2 1 1 3 3 3 3 Radial spokehead-like protein RAB3GAP2_N PF14655.1 CDJ67097.1 - 0.032 13.2 0.4 0.032 13.2 0.3 2.1 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Collagen PF01391.13 CDJ67099.1 - 0.0003 20.2 39.1 0.0003 20.2 27.1 5.3 4 1 0 4 4 4 2 Collagen triple helix repeat (20 copies) FAST_1 PF06743.10 CDJ67100.1 - 0.00037 20.1 14.4 0.12 12.0 0.0 7.0 6 1 2 8 8 8 4 FAST kinase-like protein, subdomain 1 Ribonuc_P_40 PF08584.6 CDJ67101.1 - 0.00063 18.8 0.0 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit AAA_23 PF13476.1 CDJ67102.1 - 5.4e-06 26.8 0.0 1.1e-05 25.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CDJ67102.1 - 0.00011 22.2 0.1 0.084 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CDJ67102.1 - 0.00041 20.2 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Metallophos_2 PF12850.2 CDJ67102.1 - 0.0005 19.9 0.0 0.0031 17.3 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SMC_N PF02463.14 CDJ67102.1 - 0.00055 19.2 0.0 0.0095 15.1 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CDJ67102.1 - 0.0026 17.2 0.2 0.0076 15.7 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Metallophos PF00149.23 CDJ67102.1 - 0.0092 15.3 0.1 0.069 12.5 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CDJ67103.1 - 1.1e-14 53.7 0.1 1.5e-06 27.7 0.2 3.8 3 1 2 5 5 5 4 TPR repeat TPR_2 PF07719.12 CDJ67103.1 - 1.9e-11 42.9 6.2 0.019 14.8 0.3 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ67103.1 - 1.5e-09 37.6 0.2 0.019 15.5 0.0 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ67103.1 - 3.4e-08 32.7 7.9 0.006 16.1 0.2 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ67103.1 - 3.8e-08 33.7 2.0 0.00061 20.3 0.0 4.4 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ67103.1 - 5.7e-08 31.9 0.1 0.38 10.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ67103.1 - 7.2e-08 31.6 0.6 0.1 12.3 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ67103.1 - 1.9e-07 30.8 0.9 0.00031 20.5 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ67103.1 - 1.3e-06 28.6 0.7 0.13 12.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ67103.1 - 4.4e-06 26.5 2.7 0.0015 18.3 0.2 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ67103.1 - 1.8e-05 24.9 0.1 1.9 9.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ67103.1 - 2.1e-05 24.3 0.1 5 7.5 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CDJ67103.1 - 0.00012 22.1 0.2 0.11 12.5 0.2 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CDJ67103.1 - 0.0012 18.0 0.0 0.012 14.6 0.0 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat SGT1 PF07093.6 CDJ67106.1 - 0.19 10.0 10.9 0.22 9.8 7.6 1.0 1 0 0 1 1 1 0 SGT1 protein Caps_assemb_Wzi PF14052.1 CDJ67106.1 - 0.4 9.4 4.0 0.5 9.1 2.8 1.1 1 0 0 1 1 1 0 Capsule assembly protein Wzi Herpes_LMP1 PF05297.6 CDJ67106.1 - 3 6.6 7.2 0.11 11.4 1.0 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Macoilin PF09726.4 CDJ67106.1 - 5.6 5.1 12.8 6.6 4.8 8.9 1.0 1 0 0 1 1 1 0 Transmembrane protein FCP1_C PF09309.5 CDJ67106.1 - 6.2 6.0 11.4 1.1 8.5 4.6 1.9 2 0 0 2 2 2 0 FCP1, C-terminal DEAD PF00270.24 CDJ67110.1 - 1.6e-13 50.4 6.3 4.2e-11 42.6 4.4 3.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDJ67110.1 - 4.1e-09 36.5 0.3 4.1e-09 36.5 0.2 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SPX PF03105.14 CDJ67110.1 - 0.0007 19.4 7.4 0.0007 19.4 5.2 2.9 3 0 0 3 3 3 1 SPX domain AAA_22 PF13401.1 CDJ67110.1 - 0.053 13.6 1.4 0.39 10.8 1.0 2.6 1 0 0 1 1 1 0 AAA domain Pox_P4B PF03292.9 CDJ67110.1 - 0.68 7.8 3.4 1.8 6.4 2.4 1.6 1 0 0 1 1 1 0 Poxvirus P4B major core protein 2-oxoacid_dh PF00198.18 CDJ67112.1 - 3e-43 147.7 0.0 4.9e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CDJ67112.1 - 1.4e-19 69.4 0.7 2.3e-19 68.7 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CDJ67112.1 - 6.8e-16 57.6 0.3 6.8e-16 57.6 0.2 2.2 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CDJ67112.1 - 5.3e-08 32.4 0.1 1.6e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 CDJ67112.1 - 7.9e-06 25.3 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CDJ67112.1 - 0.0023 17.1 0.2 0.0056 15.8 0.1 1.5 1 1 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 CDJ67112.1 - 0.007 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.15 CDJ67112.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PhoQ_Sensor PF08918.5 CDJ67113.1 - 1.4 8.4 3.9 2.3 7.6 2.7 1.3 1 0 0 1 1 1 0 PhoQ Sensor TFIIA PF03153.8 CDJ67113.1 - 7.1 6.4 22.3 0.43 10.4 3.4 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.1 CDJ67114.1 - 0.01 15.2 1.5 0.014 14.8 1.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 CDJ67114.1 - 4.9 5.5 9.1 6.7 5.0 6.3 1.1 1 0 0 1 1 1 0 Daxx Family Nbs1_C PF08599.5 CDJ67115.1 - 0.071 13.0 0.7 0.1 12.5 0.3 1.4 1 1 0 1 1 1 0 DNA damage repair protein Nbs1 GerA PF03323.8 CDJ67115.1 - 0.2 9.7 3.5 0.22 9.6 2.4 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DUF4544 PF15077.1 CDJ67115.1 - 0.21 11.0 2.1 0.23 10.9 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) NUC194 PF08163.7 CDJ67115.1 - 0.33 9.7 7.9 0.38 9.5 5.5 1.0 1 0 0 1 1 1 0 NUC194 domain Bestrophin PF01062.16 CDJ67115.1 - 0.42 9.5 5.2 0.48 9.3 3.6 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Act-Frag_cataly PF09192.5 CDJ67115.1 - 0.6 9.0 5.0 0.63 8.9 3.5 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Activator_LAG-3 PF11498.3 CDJ67115.1 - 2 7.0 48.4 2.4 6.8 33.5 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Peptidase_M16 PF00675.15 CDJ67115.1 - 4.7 6.9 7.9 5.4 6.7 5.5 1.2 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) DUF572 PF04502.8 CDJ67115.1 - 5.1 6.2 13.0 5.9 6.0 9.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S15 PF02129.13 CDJ67115.1 - 6.9 5.9 7.6 8.1 5.7 5.2 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SR-25 PF10500.4 CDJ67116.1 - 2.2e-05 24.0 1.0 2.2e-05 24.0 0.7 7.8 7 1 0 7 7 7 2 Nuclear RNA-splicing-associated protein P12 PF12669.2 CDJ67116.1 - 0.052 13.7 2.9 0.91 9.7 2.0 3.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Chromo PF00385.19 CDJ67118.1 - 1.2e-14 53.6 0.0 1.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo PF00385.19 CDJ67119.1 - 9.3e-11 41.2 0.0 1.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Imm37 PF15598.1 CDJ67121.1 - 0.00082 19.2 12.9 4.7 7.0 0.0 7.6 4 1 5 9 9 9 3 Immunity protein 37 Med15 PF09606.5 CDJ67123.1 - 0.18 10.0 51.0 0.21 9.7 35.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ67123.1 - 3.6 5.7 48.9 4.4 5.4 33.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Helicase_C PF00271.26 CDJ67124.1 - 6.7e-13 48.3 0.0 3.3e-12 46.0 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CDJ67124.1 - 1e-11 44.7 0.2 1e-11 44.7 0.1 3.6 3 1 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.24 CDJ67124.1 - 0.00021 20.8 0.1 0.2 11.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Med15 PF09606.5 CDJ67124.1 - 0.00025 19.4 17.5 0.00025 19.4 12.2 5.9 5 1 0 5 5 5 1 ARC105 or Med15 subunit of Mediator complex non-fungal SAPS PF04499.10 CDJ67124.1 - 2.7 6.5 19.2 1.7 7.1 0.2 3.3 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein BCS1_N PF08740.6 CDJ67125.1 - 1.1e-26 93.6 2.0 4.1e-26 91.7 0.0 2.4 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 CDJ67125.1 - 1e-12 48.4 0.0 3.1e-11 43.5 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CDJ67125.1 - 0.00076 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDJ67125.1 - 0.0035 18.1 0.0 0.0091 16.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CDJ67125.1 - 0.025 14.4 0.0 0.025 14.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 CDJ67125.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDJ67125.1 - 0.035 13.8 0.1 0.12 12.0 0.0 1.9 1 1 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 CDJ67125.1 - 0.042 14.1 3.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Miro PF08477.8 CDJ67125.1 - 0.046 14.2 0.1 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 CDJ67125.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 CDJ67125.1 - 0.074 12.7 0.6 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 CDJ67125.1 - 0.079 12.0 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 KaiC RuvB_N PF05496.7 CDJ67125.1 - 0.079 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 CDJ67125.1 - 0.12 11.9 11.9 0.81 9.2 6.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CDJ67125.1 - 0.15 12.1 1.4 0.27 11.3 0.0 2.2 3 0 0 3 3 1 0 AAA domain FCP1_C PF09309.5 CDJ67125.1 - 0.18 11.1 12.5 0.015 14.5 3.4 2.1 2 0 0 2 2 2 0 FCP1, C-terminal AAA_16 PF13191.1 CDJ67125.1 - 0.44 10.5 14.6 0.85 9.5 7.4 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 CDJ67125.1 - 0.91 9.4 0.0 0.91 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Spt20 PF12090.3 CDJ67125.1 - 1 8.6 9.3 5 6.4 4.2 2.2 2 0 0 2 2 2 0 Spt20 family AAA_23 PF13476.1 CDJ67125.1 - 5.8 7.1 13.9 38 4.5 6.0 2.9 3 0 0 3 3 3 0 AAA domain PAT1 PF09770.4 CDJ67125.1 - 7.4 4.6 29.6 3.1 5.9 15.8 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDJ67125.1 - 8 5.4 21.5 1.2 8.1 9.5 2.0 2 0 0 2 2 2 0 Fms-interacting protein Pribosyl_synth PF14572.1 CDJ67126.1 - 1.8e-08 34.3 0.3 1.9e-08 34.2 0.2 1.0 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Solute_trans_a PF03619.11 CDJ67127.1 - 4.2e-10 39.3 0.1 1.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 Organic solute transporter Ostalpha DDRGK PF09756.4 CDJ67128.1 - 0.024 14.0 21.0 0.034 13.5 14.5 1.1 1 0 0 1 1 1 0 DDRGK domain Fmp27_WPPW PF10359.4 CDJ67128.1 - 0.067 11.5 18.4 0.082 11.3 12.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF106 PF01956.11 CDJ67128.1 - 0.077 12.5 6.3 0.1 12.0 4.4 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Ycf1 PF05758.7 CDJ67128.1 - 0.2 9.3 12.8 0.23 9.1 8.9 1.0 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 CDJ67128.1 - 0.26 9.8 13.1 0.3 9.6 9.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.6 CDJ67128.1 - 0.27 10.4 8.9 0.36 9.9 6.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S49_N PF08496.5 CDJ67128.1 - 0.31 10.8 13.3 0.46 10.2 9.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Macoilin PF09726.4 CDJ67128.1 - 0.37 9.0 22.5 0.58 8.3 15.6 1.3 1 0 0 1 1 1 0 Transmembrane protein Bud13 PF09736.4 CDJ67128.1 - 0.42 10.8 15.9 0.64 10.2 11.0 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Casc1 PF12366.3 CDJ67128.1 - 0.43 10.0 12.4 0.61 9.5 8.6 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF572 PF04502.8 CDJ67128.1 - 0.57 9.3 23.6 0.76 8.9 16.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_UL87 PF03043.9 CDJ67128.1 - 0.58 8.4 6.1 0.63 8.3 4.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family CAF-1_p150 PF11600.3 CDJ67128.1 - 0.6 9.4 32.8 0.12 11.6 12.3 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4446 PF14584.1 CDJ67128.1 - 0.81 9.5 7.4 1.3 8.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3584 PF12128.3 CDJ67128.1 - 0.86 6.8 26.3 0.98 6.6 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FHIPEP PF00771.15 CDJ67128.1 - 0.95 7.7 8.3 1.5 7.0 5.7 1.3 1 0 0 1 1 1 0 FHIPEP family DUF4175 PF13779.1 CDJ67128.1 - 1 6.9 39.1 1.5 6.3 27.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1675 PF07897.6 CDJ67128.1 - 1 9.1 15.8 1.5 8.6 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SLD3 PF08639.5 CDJ67128.1 - 1.1 7.8 22.7 1.4 7.4 15.7 1.3 1 0 0 1 1 1 0 DNA replication regulator SLD3 NARP1 PF12569.3 CDJ67128.1 - 1.2 7.8 17.5 1.8 7.2 12.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF-3_zeta PF05091.7 CDJ67128.1 - 1.3 7.5 15.9 1.5 7.3 11.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Asp-B-Hydro_N PF05279.6 CDJ67128.1 - 1.6 8.5 13.2 1.8 8.3 9.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Folate_carrier PF01770.13 CDJ67128.1 - 1.7 7.0 9.8 2.9 6.2 6.8 1.3 1 0 0 1 1 1 0 Reduced folate carrier Na_trans_assoc PF06512.8 CDJ67128.1 - 1.8 8.5 14.9 2.3 8.1 10.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2232 PF09991.4 CDJ67128.1 - 2 7.3 4.6 2.8 6.8 3.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Cellulose_synt PF03552.9 CDJ67128.1 - 2 6.5 7.1 2.3 6.4 4.9 1.1 1 0 0 1 1 1 0 Cellulose synthase LMBR1 PF04791.11 CDJ67128.1 - 4.5 5.7 5.7 4.9 5.6 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HlyD_2 PF12700.2 CDJ67128.1 - 6.2 5.8 13.3 7.3 5.6 9.2 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Serinc PF03348.10 CDJ67128.1 - 9 4.8 12.9 16 4.0 8.9 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) KOW PF00467.24 CDJ67130.1 - 0.00016 21.2 0.1 0.00024 20.7 0.1 1.3 1 0 0 1 1 1 1 KOW motif SH3_2 PF07653.12 CDJ67130.1 - 0.069 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain Antitoxin-MazE PF04014.13 CDJ67130.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Peptidase_S8 PF00082.17 CDJ67131.1 - 1.9e-26 92.8 0.4 2.2e-26 92.6 0.3 1.0 1 0 0 1 1 1 1 Subtilase family MR_MLE_C PF13378.1 CDJ67131.1 - 1.4 8.8 3.9 13 5.7 0.0 2.5 2 1 0 2 2 2 0 Enolase C-terminal domain-like TraT PF05818.7 CDJ67132.1 - 0.13 11.7 10.5 0.19 11.1 7.3 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein MSP1_C PF07462.6 CDJ67132.1 - 0.46 8.8 11.5 0.57 8.5 7.9 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Mucin PF01456.12 CDJ67132.1 - 0.6 9.8 15.9 2.1 8.1 11.0 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein AAA_23 PF13476.1 CDJ67132.1 - 0.8 9.9 10.6 0.99 9.6 7.3 1.1 1 0 0 1 1 1 0 AAA domain NAM-associated PF14303.1 CDJ67132.1 - 1 9.6 15.0 1.5 9.0 10.4 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain APG6 PF04111.7 CDJ67132.1 - 1.1 8.3 12.8 1.3 7.9 8.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Caps_synth PF05704.7 CDJ67132.1 - 3.1 6.8 10.5 4.3 6.4 7.3 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Peptidase_S46 PF10459.4 CDJ67132.1 - 3.4 5.9 19.4 4.1 5.6 13.4 1.0 1 0 0 1 1 1 0 Peptidase S46 YppG PF14179.1 CDJ67132.1 - 4.2 8.0 24.9 0.41 11.2 9.5 2.3 2 0 0 2 2 2 0 YppG-like protein Med15 PF09606.5 CDJ67132.1 - 6.9 4.7 43.0 9.6 4.2 29.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4228 PF14009.1 CDJ67132.1 - 7.7 6.6 15.9 11 6.1 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Shisa PF13908.1 CDJ67133.1 - 0.00092 19.4 1.1 0.00092 19.4 0.8 3.2 1 1 1 3 3 2 1 Wnt and FGF inhibitory regulator SR-25 PF10500.4 CDJ67133.1 - 0.0015 18.0 21.3 0.0015 18.0 14.7 3.0 2 1 1 3 3 2 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 CDJ67133.1 - 0.0021 18.3 12.4 0.44 10.8 8.6 2.8 1 1 0 1 1 1 1 Dehydrin Zip PF02535.17 CDJ67133.1 - 0.015 14.3 1.2 0.15 11.0 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter TLP-20 PF06088.6 CDJ67133.1 - 0.016 14.8 0.2 0.016 14.8 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SoxE PF06525.6 CDJ67133.1 - 0.042 13.1 1.3 0.085 12.1 0.9 1.4 1 0 0 1 1 1 0 Sulfocyanin (SoxE) LMF1 PF06762.9 CDJ67133.1 - 0.053 12.3 1.5 3.4 6.3 0.2 2.1 2 0 0 2 2 2 0 Lipase maturation factor OSTbeta PF15048.1 CDJ67133.1 - 0.062 13.3 0.6 0.062 13.3 0.4 3.5 2 1 0 3 3 2 0 Organic solute transporter subunit beta protein Mtp PF03821.11 CDJ67133.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter DUF2897 PF11446.3 CDJ67133.1 - 0.19 11.6 0.1 0.19 11.6 0.1 4.5 4 1 0 4 4 3 0 Protein of unknown function (DUF2897) Mem_trans PF03547.13 CDJ67133.1 - 0.44 8.7 3.9 0.37 9.0 0.2 2.1 2 0 0 2 2 2 0 Membrane transport protein Med15 PF09606.5 CDJ67133.1 - 1.5 6.9 59.1 2 6.5 41.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM176 PF14851.1 CDJ67133.1 - 1.9 8.1 12.5 0.83 9.3 0.2 2.8 2 1 1 3 3 3 0 FAM176 family ETRAMP PF09716.5 CDJ67133.1 - 2.3 8.2 7.7 2.5 8.1 0.9 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3446 PF11928.3 CDJ67133.1 - 3.8 7.7 16.6 1.1 9.5 6.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3446) DUF2722 PF10846.3 CDJ67134.1 - 0.00083 18.4 4.8 0.018 14.0 1.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) SprA-related PF12118.3 CDJ67134.1 - 0.0028 17.0 13.7 0.0028 17.0 9.5 3.7 5 0 0 5 5 4 1 SprA-related family WD40 PF00400.27 CDJ67134.1 - 0.0046 16.8 13.5 5.1 7.1 0.0 6.0 6 1 1 7 7 7 1 WD domain, G-beta repeat Ribosomal_60s PF00428.14 CDJ67134.1 - 0.02 15.2 11.5 0.02 15.2 8.0 7.3 6 2 0 6 6 4 0 60s Acidic ribosomal protein FHIPEP PF00771.15 CDJ67134.1 - 0.076 11.3 6.9 0.027 12.8 2.8 1.6 2 0 0 2 2 2 0 FHIPEP family Suf PF05843.9 CDJ67134.1 - 0.18 11.4 9.7 0.062 13.0 1.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ctr PF04145.10 CDJ67134.1 - 0.59 10.1 4.7 2.4 8.1 1.7 2.7 3 0 0 3 3 3 0 Ctr copper transporter family TFIIA PF03153.8 CDJ67134.1 - 0.84 9.4 21.2 0.038 13.9 6.6 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Cellulose_synt PF03552.9 CDJ67134.1 - 3.7 5.7 4.3 5.3 5.2 3.0 1.1 1 0 0 1 1 1 0 Cellulose synthase R_equi_Vir PF05526.6 CDJ67134.1 - 4.4 6.8 8.8 19 4.8 6.1 2.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF4367 PF14285.1 CDJ67134.1 - 6.9 5.9 7.0 0.23 10.7 0.2 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4367) DUF4557 PF15101.1 CDJ67134.1 - 7.6 6.3 14.9 0.46 10.2 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Mob1_phocein PF03637.12 CDJ67135.1 - 1e-06 28.5 0.1 1.5e-05 24.7 0.1 2.3 2 1 0 2 2 2 1 Mob1/phocein family Asp-B-Hydro_N PF05279.6 CDJ67135.1 - 1.6 8.5 24.2 0.17 11.6 2.9 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region EIF_2_alpha PF07541.7 CDJ67136.1 - 2.1e-21 75.7 0.4 1.3e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 2 alpha subunit EspB PF05802.6 CDJ67136.1 - 0.00049 19.1 4.5 0.00076 18.5 3.1 1.3 1 0 0 1 1 1 1 Enterobacterial EspB protein Hc1 PF07432.8 CDJ67136.1 - 0.089 12.9 14.7 0.22 11.7 6.1 2.1 1 1 1 2 2 2 0 Histone H1-like protein Hc1 SNAP PF14938.1 CDJ67136.1 - 0.21 10.7 3.5 0.22 10.6 1.7 1.5 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Med13_C PF06333.7 CDJ67136.1 - 0.25 9.8 0.8 0.31 9.5 0.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Borrelia_P83 PF05262.6 CDJ67136.1 - 0.27 9.4 6.8 0.27 9.4 4.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Herpes_BLLF1 PF05109.8 CDJ67136.1 - 0.39 8.6 6.8 0.47 8.3 4.7 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TFIIF_alpha PF05793.7 CDJ67137.1 - 0.48 8.7 26.5 0.54 8.5 18.4 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_viral_N PF00242.12 CDJ67137.1 - 3.3 6.6 33.7 3.6 6.5 23.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CDJ67137.1 - 6.3 4.9 23.9 7.7 4.6 16.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Pox_Ag35 PF03286.9 CDJ67137.1 - 9.9 5.6 25.4 10 5.5 17.2 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Polysacc_synt_3 PF13440.1 CDJ67139.1 - 0.022 14.2 1.7 0.022 14.2 1.2 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2217 PF10265.4 CDJ67139.1 - 0.073 11.8 4.1 0.074 11.8 2.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4367 PF14285.1 CDJ67139.1 - 0.18 11.1 1.8 0.18 11.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) DUF1049 PF06305.6 CDJ67139.1 - 0.18 11.2 2.0 0.22 11.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3617 PF12276.3 CDJ67139.1 - 0.27 10.6 7.4 0.38 10.1 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) RskA PF10099.4 CDJ67139.1 - 0.39 10.4 15.3 0.59 9.8 10.6 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Shadoo PF14999.1 CDJ67139.1 - 0.39 10.5 13.1 0.44 10.4 9.1 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Trp_oprn_chp PF09534.5 CDJ67139.1 - 0.45 10.1 14.9 0.46 10.0 10.3 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ctr PF04145.10 CDJ67139.1 - 0.61 10.1 3.4 0.62 10.1 2.4 1.0 1 0 0 1 1 1 0 Ctr copper transporter family DUF2681 PF10883.3 CDJ67139.1 - 2 8.6 9.7 2.2 8.5 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3628 PF12300.3 CDJ67139.1 - 2.6 8.0 12.5 2.7 7.9 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) FHIPEP PF00771.15 CDJ67139.1 - 2.9 6.1 5.7 3 6.0 3.9 1.0 1 0 0 1 1 1 0 FHIPEP family DUF2782 PF11191.3 CDJ67139.1 - 3.8 7.5 8.1 5.1 7.1 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) VIT1 PF01988.14 CDJ67139.1 - 4.1 6.8 8.2 4.2 6.7 5.7 1.0 1 0 0 1 1 1 0 VIT family IncA PF04156.9 CDJ67139.1 - 4.8 6.7 10.1 7.3 6.1 7.0 1.3 1 1 0 1 1 1 0 IncA protein DUF3682 PF12446.3 CDJ67139.1 - 4.9 7.4 17.0 5.5 7.2 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3824 PF12868.2 CDJ67139.1 - 6 7.8 14.9 7 7.5 10.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) AP2 PF00847.15 CDJ67141.1 - 3.6e-13 49.4 1.3 1.1e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.1 CDJ67141.1 - 7.3e-08 32.4 0.0 7.3e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 AP2-coincident C-terminal Med15 PF09606.5 CDJ67141.1 - 6.7 4.7 114.7 0.002 16.4 60.5 3.2 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Histone PF00125.19 CDJ67143.1 - 2.6e-14 53.0 0.1 3.1e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDJ67143.1 - 0.00015 21.9 0.0 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CDJ67143.1 - 0.00034 20.4 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CDJ67143.1 - 0.00046 20.1 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CDJ67143.1 - 0.0028 16.9 0.0 0.003 16.8 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CDJ67143.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CDJ67143.1 - 0.054 13.2 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF1117 PF06547.7 CDJ67144.1 - 0.38 10.8 3.6 1 9.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) zf-CCCH PF00642.19 CDJ67145.1 - 1.9e-06 27.3 1.0 1.9e-06 27.3 0.7 3.6 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDJ67145.1 - 0.74 9.9 15.0 3.3 7.8 0.1 4.3 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Exonuc_VII_L PF02601.10 CDJ67145.1 - 1.8 7.6 56.5 0.013 14.7 9.8 2.9 2 1 1 3 3 3 0 Exonuclease VII, large subunit DNA_pol_E_B PF04042.11 CDJ67147.1 - 5e-11 42.2 0.6 1.2e-09 37.7 0.2 2.2 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B DUF2300 PF10062.4 CDJ67147.1 - 0.056 13.1 8.1 0.13 11.9 5.6 1.5 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) Chorion_2 PF03964.10 CDJ67148.1 - 9.4 6.8 16.4 0.95 10.0 2.0 2.4 1 1 1 2 2 2 0 Chorion family 2 Ion_trans_2 PF07885.11 CDJ67149.1 - 6e-12 45.1 0.4 1.9e-11 43.5 0.3 1.9 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 CDJ67149.1 - 0.02 14.1 6.1 0.037 13.2 4.2 1.4 1 0 0 1 1 1 0 Ion transport protein DUF1345 PF07077.6 CDJ67149.1 - 0.3 10.5 4.6 2.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) DUF4044 PF13253.1 CDJ67149.1 - 0.84 8.8 4.6 1.9 7.6 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) DcpS_C PF11969.3 CDJ67151.1 - 3.6e-05 23.9 0.1 0.025 14.8 0.0 3.0 3 0 0 3 3 3 2 Scavenger mRNA decapping enzyme C-term binding TFIIF_alpha PF05793.7 CDJ67151.1 - 8.3 4.6 6.7 12 4.1 4.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDP_N PF12278.3 CDJ67152.1 - 0.01 15.4 6.7 0.018 14.7 4.6 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal Vfa1 PF08432.5 CDJ67152.1 - 0.15 12.0 9.9 0.39 10.7 6.9 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.1 CDJ67152.1 - 0.17 11.6 8.0 0.27 10.9 5.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Macoilin PF09726.4 CDJ67152.1 - 0.4 8.9 21.4 0.58 8.3 14.8 1.3 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 CDJ67152.1 - 0.46 9.0 3.7 0.53 8.8 2.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_viral_N PF00242.12 CDJ67152.1 - 0.93 8.4 12.0 1.2 8.1 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ELL PF10390.4 CDJ67152.1 - 0.96 8.6 11.9 1.6 7.9 8.3 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL UPF0561 PF10573.4 CDJ67152.1 - 1.2 9.0 6.9 3.4 7.5 4.8 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 SLD3 PF08639.5 CDJ67152.1 - 1.9 7.0 16.2 2.9 6.4 11.2 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF4551 PF15087.1 CDJ67152.1 - 5.4 5.2 8.4 6.8 4.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOBP PF15279.1 CDJ67152.1 - 5.7 7.2 6.8 9.6 6.4 4.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF755 PF05501.6 CDJ67152.1 - 6 6.9 32.2 0.4 10.7 18.8 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF755) PAT1 PF09770.4 CDJ67153.1 - 0.00011 20.6 69.9 0.00011 20.5 48.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ67153.1 - 0.28 11.0 54.2 0.39 10.5 37.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AvrE PF11725.3 CDJ67153.1 - 0.63 6.9 31.5 0.63 7.0 21.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor Dicty_REP PF05086.7 CDJ67153.1 - 5.2 4.6 18.6 6.6 4.3 12.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nuc_sug_transp PF04142.10 CDJ67155.1 - 1.2e-84 283.2 4.5 1.2e-84 283.2 3.1 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 CDJ67155.1 - 8.2e-08 32.4 3.6 8.2e-08 32.4 2.5 3.2 2 2 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 CDJ67155.1 - 4.2e-07 29.7 16.9 1.9e-06 27.6 1.5 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 CDJ67155.1 - 4.8e-06 25.7 6.7 1.8e-05 23.8 4.6 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CDJ67155.1 - 7.7e-05 22.7 8.0 7.7e-05 22.7 5.6 2.9 3 1 0 3 3 3 1 EamA-like transporter family Herpes_LMP1 PF05297.6 CDJ67155.1 - 0.33 9.8 4.7 0.7 8.7 3.3 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) LCCL PF03815.14 CDJ67157.1 - 3e-33 113.6 0.4 3.1e-17 62.3 0.0 2.4 1 1 1 2 2 2 2 LCCL domain Ribosomal_60s PF00428.14 CDJ67157.1 - 5.7 7.4 10.3 0.89 10.0 3.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRXRR PF14239.1 CDJ67158.1 - 0.067 12.5 2.3 0.1 11.9 1.6 1.2 1 0 0 1 1 1 0 RRXRR protein Ribosomal_L32e PF01655.13 CDJ67159.1 - 2.6e-44 149.7 1.4 3.4e-44 149.3 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CDP-OH_P_transf PF01066.16 CDJ67160.1 - 1.6e-16 60.4 3.0 1.6e-16 60.4 2.1 3.5 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2633 PF11119.3 CDJ67160.1 - 8.5 6.1 7.3 8.9 6.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) PNP_UDP_1 PF01048.15 CDJ67161.1 - 3.5e-29 101.4 0.2 8e-29 100.2 0.0 1.6 2 0 0 2 2 2 1 Phosphorylase superfamily FLO_LFY PF01698.11 CDJ67162.1 - 0.064 12.0 15.1 0.068 12.0 10.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1705 PF08019.7 CDJ67162.1 - 0.084 12.3 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) DDHD PF02862.12 CDJ67162.1 - 0.2 11.4 16.1 0.21 11.3 11.1 1.2 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDJ67162.1 - 0.23 10.1 13.3 0.22 10.2 9.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3381 PF11861.3 CDJ67162.1 - 0.78 9.2 19.4 0.99 8.8 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FAM60A PF15396.1 CDJ67162.1 - 0.89 9.2 12.7 0.93 9.1 8.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4220 PF13968.1 CDJ67162.1 - 0.92 8.5 9.0 0.98 8.4 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Bul1_N PF04425.7 CDJ67162.1 - 1.2 7.5 14.8 1.4 7.4 10.3 1.0 1 0 0 1 1 1 0 Bul1 N terminus P5-ATPase PF12409.3 CDJ67162.1 - 1.3 8.9 7.5 1.5 8.6 5.2 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF2215 PF10225.4 CDJ67162.1 - 1.4 8.3 8.5 1.5 8.1 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Mgr1 PF08602.5 CDJ67162.1 - 1.4 7.8 8.5 1.5 7.7 5.9 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit eIF-3_zeta PF05091.7 CDJ67162.1 - 1.5 7.3 22.2 1.4 7.4 15.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF342 PF03961.8 CDJ67162.1 - 2.1 6.6 11.2 2.2 6.5 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Shadoo PF14999.1 CDJ67162.1 - 2.4 8.0 18.2 9.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective CD20 PF04103.10 CDJ67162.1 - 2.7 7.9 11.5 5.8 6.8 7.9 1.8 1 1 0 1 1 1 0 CD20-like family GAGA_bind PF06217.7 CDJ67162.1 - 2.8 7.8 23.0 3.2 7.6 15.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DcuA_DcuB PF03605.9 CDJ67162.1 - 2.8 6.6 6.5 3.3 6.4 4.5 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Neur_chan_memb PF02932.11 CDJ67162.1 - 3.5 7.4 11.1 3.5 7.4 7.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.1 CDJ67162.1 - 3.9 7.7 20.9 4.4 7.5 14.5 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_S15 PF02129.13 CDJ67162.1 - 4.8 6.5 21.3 6.5 6.0 14.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Paf1 PF03985.8 CDJ67162.1 - 4.9 5.7 22.1 5.5 5.6 15.4 1.1 1 0 0 1 1 1 0 Paf1 Ndc1_Nup PF09531.5 CDJ67162.1 - 6.3 5.0 13.6 5.8 5.2 9.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SID-1_RNA_chan PF13965.1 CDJ67162.1 - 7 4.6 9.7 6.8 4.7 6.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4011 PF13195.1 CDJ67162.1 - 7.2 6.5 12.6 10 6.1 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Med15 PF09606.5 CDJ67162.1 - 7.2 4.6 71.1 7.9 4.5 49.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ67162.1 - 7.3 4.6 52.5 7.8 4.5 36.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDJ67162.1 - 7.3 4.1 17.4 7.5 4.1 12.0 1.0 1 0 0 1 1 1 0 Ycf1 Presenilin PF01080.12 CDJ67162.1 - 7.5 5.2 14.6 8.3 5.1 10.1 1.1 1 0 0 1 1 1 0 Presenilin APG6 PF04111.7 CDJ67162.1 - 7.7 5.4 23.7 8.9 5.2 16.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Rav1p_C PF12234.3 CDJ67164.1 - 2.4e-24 85.4 3.8 3.4e-17 61.8 0.1 3.6 4 0 0 4 4 4 3 RAVE protein 1 C terminal DUF4574 PF15141.1 CDJ67166.1 - 0.051 13.3 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) PspB PF06667.7 CDJ67166.1 - 0.053 13.4 0.3 0.075 12.9 0.2 1.2 1 0 0 1 1 1 0 Phage shock protein B LPP20 PF02169.11 CDJ67166.1 - 0.096 12.7 1.2 0.13 12.3 0.8 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein BAF1_ABF1 PF04684.8 CDJ67166.1 - 0.19 10.5 10.9 0.2 10.4 7.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CcmD PF04995.9 CDJ67166.1 - 0.2 11.3 0.8 0.46 10.2 0.5 1.7 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) Suf PF05843.9 CDJ67166.1 - 0.46 10.1 3.8 0.47 10.1 2.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Surface_antigen PF11054.3 CDJ67169.1 - 1.3e-42 145.9 0.3 1.8e-42 145.4 0.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Asp_protease PF09668.5 CDJ67170.1 - 2.9e-48 162.5 0.0 5.7e-48 161.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 CDJ67170.1 - 1.4e-08 34.0 1.9 3e-08 32.9 0.0 2.3 2 0 0 2 2 1 1 Ubiquitin family Asp_protease_2 PF13650.1 CDJ67170.1 - 1e-07 32.3 0.0 2.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ67170.1 - 4.4e-06 26.4 0.1 2.1e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ67170.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 CDJ67170.1 - 0.00021 20.9 0.5 0.00055 19.5 0.0 2.0 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 CDJ67170.1 - 0.0032 17.3 0.6 0.029 14.2 0.0 2.6 2 1 0 2 2 2 1 Retroviral aspartyl protease CPSF73-100_C PF11718.3 CDJ67170.1 - 0.0034 16.7 1.5 0.0057 16.0 0.3 1.9 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term INO80_Ies4 PF08193.6 CDJ67170.1 - 0.0071 16.3 0.4 0.0071 16.3 0.3 1.9 2 0 0 2 2 2 1 INO80 complex subunit Ies4 Spt20 PF12090.3 CDJ67170.1 - 0.031 13.6 1.2 0.12 11.7 0.7 2.0 2 0 0 2 2 2 0 Spt20 family ERp29 PF07749.7 CDJ67170.1 - 0.047 14.3 1.0 0.13 12.8 0.7 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Pex14_N PF04695.8 CDJ67170.1 - 0.12 12.3 7.1 1.3 9.0 1.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAB3GAP2_N PF14655.1 CDJ67170.1 - 0.66 8.9 7.1 0.56 9.1 1.8 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DEAD PF00270.24 CDJ67171.1 - 4.1e-10 39.4 1.8 5.2e-09 35.8 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Dehydrin PF00257.14 CDJ67171.1 - 0.057 13.7 9.0 0.82 9.9 0.0 3.3 2 1 1 3 3 3 0 Dehydrin HECT PF00632.20 CDJ67172.1 - 4e-72 243.0 0.0 7.7e-72 242.1 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.13 CDJ67172.1 - 1e-30 105.6 12.1 1.8e-07 31.2 0.0 7.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ67172.1 - 2.2e-22 78.1 21.3 5.1e-07 29.1 0.0 6.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Copine PF07002.11 CDJ67172.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Copine R_equi_Vir PF05526.6 CDJ67172.1 - 1.2 8.7 7.7 0.54 9.8 0.0 3.4 3 0 0 3 3 3 0 Rhodococcus equi virulence-associated protein Cu2_monoox_C PF03712.10 CDJ67172.1 - 8.4 5.7 6.2 3.5 6.9 2.2 1.9 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain tRNA-synt_1c PF00749.16 CDJ67173.1 - 9.7e-98 326.6 0.0 9.7e-98 326.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CDJ67173.1 - 3.1e-47 160.4 0.0 7.7e-47 159.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain MFS_1 PF07690.11 CDJ67174.1 - 4.7e-13 48.5 20.4 4.9e-12 45.2 14.0 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 CDJ67174.1 - 0.001 18.4 0.6 0.21 11.0 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1049) FAM176 PF14851.1 CDJ67174.1 - 0.0046 16.6 0.1 0.12 12.0 0.1 2.4 2 0 0 2 2 2 1 FAM176 family DUF2681 PF10883.3 CDJ67174.1 - 0.041 14.0 0.5 0.13 12.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) MAS20 PF02064.10 CDJ67174.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor DUF2040 PF09745.4 CDJ67175.1 - 7.5e-17 61.3 19.3 1.6e-16 60.3 6.4 2.9 4 0 0 4 4 4 2 Coiled-coil domain-containing protein 55 (DUF2040) XRN_N PF03159.13 CDJ67176.1 - 1.8e-46 158.4 0.6 2.7e-39 134.9 0.0 3.9 3 1 0 3 3 3 2 XRN 5'-3' exonuclease N-terminus Aldo_ket_red PF00248.16 CDJ67177.1 - 2.3e-46 157.8 0.0 5.1e-42 143.6 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family PP2C PF00481.16 CDJ67178.1 - 5.5e-19 68.5 0.1 1.9e-15 56.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C DUF2201_N PF13203.1 CDJ67178.1 - 0.0061 15.7 2.5 0.0061 15.7 1.7 2.4 3 0 0 3 3 3 1 Putative metallopeptidase domain SR-25 PF10500.4 CDJ67178.1 - 0.51 9.7 21.3 0.013 14.9 8.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PPR_2 PF13041.1 CDJ67179.1 - 8.8e-10 38.4 0.1 3.3e-08 33.3 0.0 2.4 1 1 1 2 2 2 1 PPR repeat family PPR_3 PF13812.1 CDJ67179.1 - 3.6e-05 23.7 3.2 0.083 13.2 0.2 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain UreF PF01730.11 CDJ67179.1 - 0.0013 18.8 1.0 0.0021 18.1 0.7 1.4 1 0 0 1 1 1 1 UreF PPR PF01535.15 CDJ67179.1 - 0.0029 17.4 0.3 0.19 11.7 0.0 2.8 2 1 0 2 2 2 1 PPR repeat PPR_1 PF12854.2 CDJ67179.1 - 0.01 15.2 0.1 0.53 9.8 0.0 2.6 3 0 0 3 3 3 0 PPR repeat UPF1_Zn_bind PF09416.5 CDJ67179.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) DUF433 PF04255.9 CDJ67181.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) LpxK PF02606.9 CDJ67181.1 - 0.13 11.1 0.4 0.17 10.8 0.3 1.0 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Thioredoxin_4 PF13462.1 CDJ67181.1 - 0.4 10.6 2.3 0.57 10.1 1.6 1.2 1 0 0 1 1 1 0 Thioredoxin TSA PF03249.8 CDJ67181.1 - 1 7.8 6.1 1.2 7.5 4.2 1.0 1 0 0 1 1 1 0 Type specific antigen DUF1183 PF06682.7 CDJ67182.1 - 2.2 7.7 15.9 5.7 6.4 11.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2681 PF10883.3 CDJ67182.1 - 7.2 6.8 44.5 0.054 13.6 0.6 5.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2681) zf-CCHC_2 PF13696.1 CDJ67183.1 - 3.2e-06 26.5 0.4 6.3e-06 25.5 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.1 CDJ67183.1 - 0.016 15.0 10.5 0.041 13.7 7.3 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CDJ67183.1 - 2.5 8.2 18.3 0.025 14.5 7.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PAT1 PF09770.4 CDJ67184.1 - 9.4 4.3 25.0 11 4.1 17.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ras PF00071.17 CDJ67185.1 - 1.5e-36 125.2 8.9 1.2e-18 66.9 3.5 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CDJ67185.1 - 3.1e-15 56.7 1.3 4.1e-08 33.7 0.9 2.4 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 CDJ67185.1 - 9.7e-08 31.4 2.3 1.1e-05 24.7 0.6 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Med15 PF09606.5 CDJ67185.1 - 0.00029 19.2 16.6 0.00029 19.2 11.5 2.0 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ67185.1 - 0.00054 19.3 0.4 0.0019 17.5 0.0 2.0 2 0 0 2 2 2 1 Spt20 family AAA_22 PF13401.1 CDJ67185.1 - 0.0033 17.5 0.3 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain FimP PF09766.4 CDJ67185.1 - 0.011 14.8 8.2 0.018 14.1 5.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein PduV-EutP PF10662.4 CDJ67185.1 - 0.014 14.8 0.2 0.077 12.4 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CD20 PF04103.10 CDJ67185.1 - 0.018 14.9 0.3 0.054 13.4 0.1 1.8 2 0 0 2 2 2 0 CD20-like family TFIIA PF03153.8 CDJ67185.1 - 0.018 14.9 12.2 0.018 14.9 8.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MMR_HSR1 PF01926.18 CDJ67185.1 - 0.019 14.9 0.0 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Shadoo PF14999.1 CDJ67185.1 - 0.02 14.7 2.0 0.02 14.7 1.4 3.1 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDJ67185.1 - 0.036 14.4 37.2 0.036 14.4 8.2 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA_29 PF13555.1 CDJ67185.1 - 0.07 12.6 1.3 0.17 11.4 0.0 2.3 2 0 0 2 2 1 0 P-loop containing region of AAA domain Claudin_2 PF13903.1 CDJ67185.1 - 0.073 12.7 5.7 0.13 11.9 3.9 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction FHIPEP PF00771.15 CDJ67185.1 - 0.089 11.1 6.8 0.13 10.5 4.7 1.2 1 0 0 1 1 1 0 FHIPEP family DUF1980 PF09323.5 CDJ67185.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) AAA_5 PF07728.9 CDJ67185.1 - 0.13 12.0 0.2 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NDUF_B5 PF09781.4 CDJ67185.1 - 0.14 11.4 2.7 0.32 10.2 1.9 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Hpr_kinase_C PF07475.7 CDJ67185.1 - 0.16 11.2 1.6 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF3373 PF11853.3 CDJ67185.1 - 0.2 10.1 8.3 0.39 9.2 5.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) MobB PF03205.9 CDJ67185.1 - 0.23 11.1 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 CDJ67185.1 - 0.6 9.0 3.6 0.83 8.6 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 CDJ67185.1 - 0.61 9.6 5.4 2.4 7.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain Serinc PF03348.10 CDJ67185.1 - 0.66 8.6 3.5 1.1 7.9 2.4 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.9 CDJ67185.1 - 0.9 9.2 11.1 0.49 10.0 5.0 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ABC_tran PF00005.22 CDJ67185.1 - 1.4 9.2 0.0 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 ABC transporter SAGA-Tad1 PF12767.2 CDJ67185.1 - 1.7 8.2 10.5 0.21 11.2 3.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Ctr PF04145.10 CDJ67185.1 - 2.8 7.9 6.2 1.1 9.2 1.1 2.1 2 0 0 2 2 2 0 Ctr copper transporter family AIF_C PF14721.1 CDJ67185.1 - 3.8 7.7 8.5 0.44 10.7 2.3 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PSK PF06404.7 CDJ67185.1 - 9.9 7.0 12.4 3.4 8.5 3.4 2.6 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) AAA_23 PF13476.1 CDJ67186.1 - 0.0048 17.2 4.9 0.028 14.7 0.3 2.3 2 0 0 2 2 2 2 AAA domain Dehydratase_MU PF02288.10 CDJ67188.1 - 0.02 14.5 5.3 0.033 13.9 3.7 1.4 1 1 0 1 1 1 0 Dehydratase medium subunit YliH PF10799.3 CDJ67188.1 - 2.1 8.0 5.0 0.46 10.1 1.0 1.7 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) Sedlin_N PF04628.8 CDJ67189.1 - 1.1e-15 57.6 0.0 1.4e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CDJ67189.1 - 0.015 15.0 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Sybindin-like family Macoilin PF09726.4 CDJ67190.1 - 2.7 6.1 5.3 4.2 5.5 3.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1517 PF07466.6 CDJ67190.1 - 5.6 5.8 12.4 1.2 8.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Enolase_C PF00113.17 CDJ67195.1 - 7.1e-144 478.2 0.0 1.1e-143 477.6 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CDJ67195.1 - 9.1e-49 164.7 0.5 9.1e-49 164.7 0.4 4.4 5 0 0 5 5 1 1 Enolase, N-terminal domain DUF3645 PF12359.3 CDJ67195.1 - 6.6e-17 60.3 0.1 1.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.1 CDJ67195.1 - 6.5e-06 26.1 0.2 2.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CDJ67195.1 - 1.5e-05 24.4 0.6 0.55 10.2 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain MAAL_C PF07476.6 CDJ67195.1 - 8.1e-05 21.6 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus EF-hand_1 PF00036.27 CDJ67195.1 - 0.00013 20.9 0.0 0.0032 16.6 0.1 2.5 2 0 0 2 2 2 1 EF hand MR_MLE_C PF13378.1 CDJ67195.1 - 0.00087 19.2 0.0 0.00087 19.2 0.0 6.5 8 1 1 9 9 8 1 Enolase C-terminal domain-like EF-hand_8 PF13833.1 CDJ67195.1 - 0.0056 16.2 0.0 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair DUF946 PF06101.6 CDJ67195.1 - 0.059 11.3 0.0 0.098 10.6 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) EF-hand_5 PF13202.1 CDJ67195.1 - 0.092 12.1 0.2 0.24 10.8 0.1 1.7 1 0 0 1 1 1 0 EF hand B5 PF03484.10 CDJ67196.1 - 8.1e-12 44.8 0.0 1.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase B5 domain B3_4 PF03483.12 CDJ67196.1 - 2.1e-06 27.2 0.2 6.5e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 B3/4 domain RNA_pol_Rpc4 PF05132.9 CDJ67196.1 - 0.0084 16.1 0.2 0.016 15.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 Adaptin_N PF01602.15 CDJ67196.1 - 0.049 11.9 0.0 0.071 11.4 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Med3 PF11593.3 CDJ67198.1 - 1 8.5 8.7 1.1 8.4 6.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF755 PF05501.6 CDJ67198.1 - 1.9 8.5 8.6 0.48 10.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Clat_adaptor_s PF01217.15 CDJ67199.1 - 1.5e-44 151.1 1.2 1.6e-44 151.0 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 CDJ67200.1 - 1.8e-47 161.6 0.2 2.3e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67200.1 - 1.6e-29 102.7 0.2 2e-29 102.4 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDJ67200.1 - 0.00021 21.1 0.0 0.024 14.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CDJ67200.1 - 0.008 15.2 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CDJ67200.1 - 0.063 12.6 0.1 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF4565 PF15127.1 CDJ67200.1 - 0.064 13.5 0.3 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4565) Kinase-like PF14531.1 CDJ67200.1 - 0.12 11.3 0.1 1 8.2 0.0 2.0 1 1 0 2 2 2 0 Kinase-like Ribosomal_60s PF00428.14 CDJ67200.1 - 6 7.3 12.1 11 6.4 5.9 2.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.17 CDJ67201.1 - 4.8e-21 74.1 0.1 7.3e-21 73.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ67201.1 - 1.9e-16 59.7 0.1 3e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 CDJ67201.1 - 4.2e-15 55.8 3.5 4.2e-15 55.8 2.4 2.6 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 CDJ67201.1 - 1.2e-10 41.0 0.0 2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF743 PF05332.6 CDJ67201.1 - 0.0079 16.1 0.1 0.0079 16.1 0.1 2.2 2 1 0 3 3 3 1 Protein of unknown function (DUF743) Hairy_orange PF07527.8 CDJ67201.1 - 0.032 13.9 0.3 0.052 13.2 0.2 1.4 1 0 0 1 1 1 0 Hairy Orange RRM_1 PF00076.17 CDJ67202.1 - 3.9e-26 90.4 0.0 1.5e-16 59.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ67202.1 - 8.8e-24 83.2 0.0 6.2e-12 45.3 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ67202.1 - 2.5e-11 43.2 0.0 0.00092 19.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TraT PF05818.7 CDJ67205.1 - 0.0001 21.8 7.3 0.00012 21.5 5.0 1.0 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein DUF3617 PF12276.3 CDJ67205.1 - 0.0036 16.7 14.7 0.0045 16.4 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3617) Shadoo PF14999.1 CDJ67205.1 - 0.0047 16.7 4.8 0.005 16.6 3.4 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective FimP PF09766.4 CDJ67205.1 - 0.0084 15.2 16.3 0.0087 15.1 11.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein Cid2 PF09774.4 CDJ67205.1 - 0.052 13.6 11.1 0.052 13.6 7.7 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 N6_N4_Mtase PF01555.13 CDJ67205.1 - 0.11 12.0 1.8 0.1 12.0 1.2 1.0 1 0 0 1 1 1 0 DNA methylase FerI PF08151.7 CDJ67205.1 - 0.12 12.4 2.6 0.31 11.1 1.8 1.7 1 1 0 1 1 1 0 FerI (NUC094) domain Suf PF05843.9 CDJ67205.1 - 0.12 12.1 13.6 0.12 12.0 9.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cyclin_C PF02984.14 CDJ67205.1 - 0.14 12.1 7.3 0.2 11.6 5.0 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain PAT1 PF09770.4 CDJ67205.1 - 0.15 10.2 21.8 0.12 10.5 15.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CIAPIN1 PF05093.8 CDJ67205.1 - 0.18 11.9 5.3 0.22 11.6 3.7 1.3 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Spt20 PF12090.3 CDJ67205.1 - 0.19 11.0 11.9 0.22 10.8 8.3 1.3 1 0 0 1 1 1 0 Spt20 family Ctr PF04145.10 CDJ67205.1 - 0.21 11.6 4.1 0.24 11.4 2.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family FAM176 PF14851.1 CDJ67205.1 - 0.21 11.2 7.3 0.25 11.0 5.1 1.1 1 0 0 1 1 1 0 FAM176 family Activator_LAG-3 PF11498.3 CDJ67205.1 - 0.23 10.1 32.6 0.23 10.1 22.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Porin_4 PF13609.1 CDJ67205.1 - 0.26 10.7 6.4 0.3 10.5 4.4 1.1 1 0 0 1 1 1 0 Gram-negative porin Med15 PF09606.5 CDJ67205.1 - 0.28 9.3 36.4 0.29 9.2 25.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.15 CDJ67205.1 - 0.29 9.4 5.6 0.3 9.3 3.9 1.0 1 0 0 1 1 1 0 FHIPEP family HemX PF04375.9 CDJ67205.1 - 0.31 9.5 19.2 0.32 9.5 13.3 1.0 1 0 0 1 1 1 0 HemX Peptidase_S49_N PF08496.5 CDJ67205.1 - 0.33 10.7 6.4 0.34 10.6 4.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF819 PF05684.7 CDJ67205.1 - 0.34 9.6 1.8 0.41 9.4 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) DDRGK PF09756.4 CDJ67205.1 - 0.36 10.2 13.0 0.36 10.2 9.0 1.1 1 0 0 1 1 1 0 DDRGK domain Cellulose_synt PF03552.9 CDJ67205.1 - 0.46 8.7 4.7 0.49 8.6 3.3 1.0 1 0 0 1 1 1 0 Cellulose synthase Gag_spuma PF03276.9 CDJ67205.1 - 0.47 8.7 20.0 0.41 8.9 13.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein ERF PF04404.7 CDJ67205.1 - 0.49 9.9 15.9 0.59 9.6 11.0 1.3 1 0 0 1 1 1 0 ERF superfamily HA2 PF04408.18 CDJ67205.1 - 0.5 10.4 2.4 0.62 10.1 1.7 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) DUF2232 PF09991.4 CDJ67205.1 - 0.55 9.1 2.2 0.62 8.9 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) YjeF_N PF03853.10 CDJ67205.1 - 0.57 9.7 5.4 0.68 9.5 3.8 1.2 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF4557 PF15101.1 CDJ67205.1 - 0.68 9.7 20.8 0.75 9.5 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Dala_Dala_lig_N PF01820.16 CDJ67205.1 - 0.74 10.1 5.6 0.77 10.0 3.9 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Spore_YhcN_YlaJ PF09580.5 CDJ67205.1 - 0.86 9.6 10.4 0.85 9.7 7.2 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1669 PF07894.7 CDJ67205.1 - 0.86 8.7 7.7 0.97 8.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) R_equi_Vir PF05526.6 CDJ67205.1 - 0.87 9.1 9.8 1 8.9 6.8 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Band_3_cyto PF07565.8 CDJ67205.1 - 0.92 8.9 9.8 0.98 8.8 6.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2215 PF10225.4 CDJ67205.1 - 1.1 8.6 4.0 1.2 8.4 2.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Serinc PF03348.10 CDJ67205.1 - 1.1 7.8 9.6 1.2 7.7 6.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF775 PF05603.7 CDJ67205.1 - 1.2 8.6 12.1 1.2 8.6 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) zf-DHHC PF01529.15 CDJ67205.1 - 1.3 8.4 4.7 1.3 8.3 3.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase FLO_LFY PF01698.11 CDJ67205.1 - 1.3 7.7 11.9 1.4 7.7 8.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Bac_luciferase PF00296.15 CDJ67205.1 - 1.4 8.0 11.1 1.4 7.9 7.7 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Hid1 PF12722.2 CDJ67205.1 - 1.5 6.4 8.3 1.3 6.5 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Wzz PF02706.10 CDJ67205.1 - 1.5 8.6 7.2 1.9 8.2 5.0 1.1 1 0 0 1 1 1 0 Chain length determinant protein eIF-3_zeta PF05091.7 CDJ67205.1 - 1.6 7.2 13.4 1.5 7.3 9.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.12 CDJ67205.1 - 1.9 8.1 9.1 1.9 8.2 6.3 1.1 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.8 CDJ67205.1 - 2 8.2 23.8 2.2 8.0 16.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 CDJ67205.1 - 2.3 8.0 10.1 2.3 8.0 7.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OATP PF03137.15 CDJ67205.1 - 2.4 6.0 6.9 2.3 6.1 4.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S15 PF02129.13 CDJ67205.1 - 2.4 7.4 10.9 2.6 7.3 7.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PBP_sp32 PF07222.7 CDJ67205.1 - 2.6 7.1 14.4 2.4 7.2 10.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Glyco_transf_15 PF01793.11 CDJ67205.1 - 2.8 6.7 8.3 2.9 6.7 5.7 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF3371 PF11851.3 CDJ67205.1 - 2.9 8.5 15.6 3.5 8.3 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF788 PF05620.6 CDJ67205.1 - 3.1 7.6 10.1 3.3 7.5 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF1071 PF06378.6 CDJ67205.1 - 3.3 6.8 9.8 4.1 6.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Neur_chan_memb PF02932.11 CDJ67205.1 - 3.8 7.3 4.9 3.8 7.3 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paf1 PF03985.8 CDJ67205.1 - 4.4 5.9 13.9 4.3 5.9 9.6 1.0 1 0 0 1 1 1 0 Paf1 RED_N PF07808.8 CDJ67205.1 - 4.8 6.3 17.7 6.1 5.9 12.3 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Scs3p PF10261.4 CDJ67205.1 - 5.8 5.8 8.2 7.1 5.5 5.7 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF4544 PF15077.1 CDJ67205.1 - 7.2 6.0 7.3 7 6.0 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Pox_P4B PF03292.9 CDJ67205.1 - 7.5 4.3 7.5 8.3 4.2 5.2 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein UPF0560 PF10577.4 CDJ67205.1 - 7.6 4.6 19.7 7.3 4.7 13.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 G-alpha PF00503.15 CDJ67207.1 - 5e-05 22.1 1.8 6.2e-05 21.8 1.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 CDJ67207.1 - 0.00089 18.7 0.0 0.0028 17.1 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.17 CDJ67207.1 - 0.0016 17.3 0.1 0.002 17.0 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 CDJ67207.1 - 0.0028 18.4 0.2 0.0042 17.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDJ67207.1 - 0.004 17.1 0.1 0.004 17.1 0.1 2.6 1 1 1 2 2 1 1 AAA ATPase domain NACHT PF05729.7 CDJ67207.1 - 0.0072 15.9 0.4 0.012 15.3 0.3 1.4 1 0 0 1 1 1 1 NACHT domain ATP_bind_1 PF03029.12 CDJ67207.1 - 0.0076 15.8 0.4 0.01 15.3 0.3 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein T2SE PF00437.15 CDJ67207.1 - 0.01 14.7 0.1 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 CDJ67207.1 - 0.015 15.4 0.1 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CDJ67207.1 - 0.015 14.7 0.3 0.022 14.1 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CDJ67207.1 - 0.02 14.6 0.3 0.028 14.1 0.2 1.2 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 CDJ67207.1 - 0.042 14.1 0.3 0.057 13.7 0.2 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CDJ67207.1 - 0.044 13.2 0.1 0.088 12.3 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 CDJ67207.1 - 0.048 12.7 0.7 0.071 12.1 0.2 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CDJ67207.1 - 0.068 13.0 0.3 0.068 13.0 0.2 2.1 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 CDJ67207.1 - 0.078 12.6 0.1 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 CDJ67207.1 - 0.11 12.2 0.3 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CDJ67207.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CDJ67207.1 - 0.18 11.6 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Corona_nucleoca PF00937.13 CDJ67207.1 - 1.1 8.1 8.2 1.6 7.6 5.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein TFIIA PF03153.8 CDJ67207.1 - 1.6 8.5 15.2 2.1 8.1 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S4 PF00163.14 CDJ67209.1 - 4.5e-07 30.1 1.4 4.5e-07 30.1 0.9 2.0 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CDJ67209.1 - 0.016 14.6 1.3 0.12 11.8 0.2 2.2 2 0 0 2 2 2 0 S4 domain YqzE PF14038.1 CDJ67209.1 - 9.6 6.0 8.2 27 4.6 5.7 1.7 1 0 0 1 1 1 0 YqzE-like protein Ribosomal_S28e PF01200.13 CDJ67210.1 - 2.5e-31 107.1 2.5 2.7e-31 107.0 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e SNF2_N PF00176.18 CDJ67211.1 - 1.8e-32 112.3 3.0 3.2e-32 111.5 1.7 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CDJ67211.1 - 1.7e-06 28.0 8.0 3.9e-06 26.8 5.5 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2413 PF10310.4 CDJ67211.1 - 0.00091 18.1 14.1 0.00091 18.1 9.7 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2413) AAA_11 PF13086.1 CDJ67211.1 - 0.0086 15.6 13.3 0.014 14.9 8.1 2.1 2 0 0 2 2 2 1 AAA domain DUF913 PF06025.7 CDJ67211.1 - 0.085 11.5 11.6 0.18 10.4 8.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_14 PF13173.1 CDJ67211.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 CDJ67211.1 - 0.74 7.4 11.0 1 7.0 7.6 1.2 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CDJ67211.1 - 0.75 7.7 14.7 1.4 6.9 10.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.1 CDJ67211.1 - 0.96 8.3 26.4 0.14 11.0 13.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Hid1 PF12722.2 CDJ67211.1 - 1.1 6.8 16.7 1.8 6.1 11.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 CDJ67211.1 - 1.3 7.2 2.9 2.2 6.4 2.0 1.4 1 0 0 1 1 1 0 Membrane transport protein SR-25 PF10500.4 CDJ67211.1 - 1.4 8.3 32.8 1.3 8.4 11.7 2.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SAPS PF04499.10 CDJ67211.1 - 1.9 6.9 14.5 4.1 5.9 10.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FLO_LFY PF01698.11 CDJ67211.1 - 5.9 5.6 17.9 13 4.4 12.4 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein Nucleoside_tran PF01733.13 CDJ67211.1 - 7 5.7 4.6 13 4.7 3.2 1.4 1 0 0 1 1 1 0 Nucleoside transporter TFIIF_alpha PF05793.7 CDJ67214.1 - 0.0016 16.9 18.6 0.0026 16.2 12.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF755 PF05501.6 CDJ67214.1 - 0.0039 17.2 43.7 0.0039 17.2 30.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF755) Macoilin PF09726.4 CDJ67214.1 - 0.0072 14.6 21.1 0.0096 14.2 14.6 1.2 1 0 0 1 1 1 1 Transmembrane protein Sec3_C PF09763.4 CDJ67214.1 - 0.013 13.6 11.3 0.017 13.2 7.9 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 FAM60A PF15396.1 CDJ67214.1 - 0.054 13.2 21.6 0.016 14.9 12.8 1.7 2 0 0 2 2 2 0 Protein Family FAM60A DUF4603 PF15376.1 CDJ67214.1 - 0.11 9.6 22.6 0.15 9.2 15.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SR-25 PF10500.4 CDJ67214.1 - 0.4 10.1 57.2 0.15 11.5 37.2 2.0 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nucleo_P87 PF07267.6 CDJ67214.1 - 0.49 9.0 7.7 0.63 8.6 5.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MFMR PF07777.6 CDJ67214.1 - 1.1 9.1 21.0 2 8.3 14.6 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR Hid1 PF12722.2 CDJ67214.1 - 1.9 6.0 15.6 1.9 6.0 10.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF566 PF04484.7 CDJ67214.1 - 2.4 7.6 24.8 3.1 7.2 17.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Raftlin PF15250.1 CDJ67214.1 - 4.4 5.7 15.4 8 4.8 10.7 1.4 1 0 0 1 1 1 0 Raftlin HHV6-IE PF03753.8 CDJ67214.1 - 4.9 4.5 14.5 6.4 4.1 10.0 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein CDC45 PF02724.9 CDJ67214.1 - 8.3 4.3 21.3 13 3.6 14.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Dehydrin PF00257.14 CDJ67218.1 - 0.025 14.9 0.4 0.045 14.0 0.2 1.4 1 0 0 1 1 1 0 Dehydrin Lin-8 PF03353.10 CDJ67218.1 - 0.061 12.6 4.9 0.078 12.2 3.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AAA_28 PF13521.1 CDJ67218.1 - 0.16 11.9 2.4 0.41 10.6 1.6 1.7 1 1 0 1 1 1 0 AAA domain CDC45 PF02724.9 CDJ67218.1 - 0.92 7.4 7.8 1.6 6.6 5.4 1.3 1 1 0 1 1 1 0 CDC45-like protein VirionAssem_T7 PF11653.3 CDJ67218.1 - 8.1 7.2 15.4 2.8 8.7 1.0 2.3 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein HMG_box PF00505.14 CDJ67219.1 - 3.9e-12 46.2 2.3 3.9e-12 46.2 1.6 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDJ67219.1 - 9.7e-05 22.6 1.8 9.7e-05 22.6 1.2 3.0 2 1 1 3 3 3 1 HMG-box domain SET PF00856.23 CDJ67219.1 - 0.0053 17.0 0.1 0.0053 17.0 0.1 5.2 3 3 0 3 3 3 1 SET domain ubiquitin PF00240.18 CDJ67220.1 - 3.7e-60 199.2 4.0 4.3e-35 118.9 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CDJ67220.1 - 2.1e-33 113.8 2.1 2.3e-20 72.0 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDJ67220.1 - 1.1e-10 41.5 0.5 8.9e-06 25.8 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CDJ67220.1 - 6.5e-07 29.2 0.0 0.019 14.8 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 CDJ67220.1 - 2.5e-05 24.0 0.0 0.00047 19.8 0.0 2.0 2 0 0 2 2 2 1 Telomere stability and silencing DUF2870 PF11069.3 CDJ67220.1 - 3.4e-05 23.8 0.0 0.37 10.8 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2870) DUF2407 PF10302.4 CDJ67220.1 - 4e-05 23.7 0.1 0.047 13.8 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 CDJ67220.1 - 0.021 14.7 0.2 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Plexin_cytopl PF08337.7 CDJ67220.1 - 0.12 10.6 0.5 2.1 6.5 0.1 2.4 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Yip1 PF04893.12 CDJ67221.1 - 0.0043 16.5 0.5 0.0066 15.9 0.4 1.3 1 0 0 1 1 1 1 Yip1 domain PHO4 PF01384.15 CDJ67221.1 - 0.018 13.7 1.0 0.49 8.9 0.2 2.1 1 1 1 2 2 2 0 Phosphate transporter family MatE PF01554.13 CDJ67221.1 - 0.035 13.7 1.1 0.046 13.3 0.1 1.7 2 0 0 2 2 2 0 MatE DUF3139 PF11337.3 CDJ67221.1 - 0.18 12.0 1.2 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DUF1049 PF06305.6 CDJ67221.1 - 0.61 9.6 4.6 0.11 12.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Ndc1_Nup PF09531.5 CDJ67226.1 - 0.74 8.1 3.5 1.1 7.5 2.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.20 CDJ67228.1 - 0.0009 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67228.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.1 CDJ67228.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Sec63 PF02889.11 CDJ67229.1 - 1.8e-58 198.2 0.4 3.2e-58 197.4 0.2 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CDJ67229.1 - 6.2e-28 97.4 0.1 3.1e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ67229.1 - 6e-09 35.6 0.0 1.5e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDJ67229.1 - 1.1e-08 35.1 0.4 2.7e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sec63 PF02889.11 CDJ67230.1 - 1.8e-44 152.2 0.0 6.3e-37 127.4 0.0 3.2 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 CDJ67230.1 - 8.5e-16 57.9 0.0 1.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ67230.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SR-25 PF10500.4 CDJ67230.1 - 3.8 6.9 6.3 6.2 6.2 4.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tmemb_cc2 PF10267.4 CDJ67231.1 - 0.2 10.2 0.8 0.23 10.0 0.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4578 PF15147.1 CDJ67233.1 - 0.063 13.6 0.3 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) DUF2217 PF10265.4 CDJ67233.1 - 0.19 10.4 3.4 0.24 10.1 2.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Opi1 PF08618.5 CDJ67233.1 - 2.2 7.0 14.7 2.8 6.7 10.2 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 gag-asp_proteas PF13975.1 CDJ67235.1 - 3.2e-08 33.2 0.0 6.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ67235.1 - 8.9e-08 32.5 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDJ67235.1 - 3e-06 27.0 0.0 6.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ67235.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ67235.1 - 0.0029 17.1 0.0 0.0058 16.1 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CDJ67236.1 - 4.6e-06 26.2 18.9 0.0012 18.6 2.0 3.5 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_2 PF13696.1 CDJ67236.1 - 0.00022 20.6 9.7 0.031 13.7 0.4 3.5 3 0 0 3 3 3 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ67236.1 - 0.0079 16.2 3.5 0.017 15.1 2.5 1.5 1 0 0 1 1 1 1 DnaJ central domain zf-CCHC_3 PF13917.1 CDJ67236.1 - 0.0096 15.6 2.3 0.099 12.3 0.2 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.1 CDJ67236.1 - 0.013 14.9 0.8 0.013 14.9 0.6 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.3 CDJ67236.1 - 2 8.3 5.2 6.5 6.6 0.6 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 CDJ67236.1 - 6.5 6.5 9.4 4.4 7.0 0.5 2.9 3 0 0 3 3 3 0 Zinc knuckle BAF1_ABF1 PF04684.8 CDJ67237.1 - 0.0026 16.6 17.1 0.0026 16.6 11.9 2.3 1 1 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 CDJ67237.1 - 0.077 12.0 3.6 0.099 11.6 2.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein TFIIA PF03153.8 CDJ67237.1 - 0.33 10.8 12.1 0.39 10.5 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.3 CDJ67237.1 - 0.36 10.1 2.7 0.47 9.7 1.9 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDJ67237.1 - 0.45 10.2 4.8 0.57 9.8 3.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1071 PF06378.6 CDJ67237.1 - 0.49 9.5 3.8 0.73 8.9 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) PAT1 PF09770.4 CDJ67237.1 - 0.6 8.2 18.7 0.72 8.0 12.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hamartin PF04388.7 CDJ67237.1 - 4 5.9 6.0 6.2 5.3 4.2 1.4 1 0 0 1 1 1 0 Hamartin protein gag-asp_proteas PF13975.1 CDJ67238.1 - 6.7e-09 35.4 0.0 1.8e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ67238.1 - 1.8e-08 34.7 0.0 3.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDJ67238.1 - 1.7e-06 27.8 0.0 3.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 CDJ67238.1 - 4.8e-05 23.0 0.7 9.2e-05 22.1 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 CDJ67238.1 - 0.0019 18.1 0.0 0.015 15.1 0.0 2.3 3 0 0 3 3 3 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ67238.1 - 0.0026 17.3 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF4636 PF15468.1 CDJ67240.1 - 0.12 11.8 6.8 0.13 11.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Velvet PF11754.3 CDJ67240.1 - 0.45 10.0 8.3 0.51 9.9 5.7 1.3 1 1 0 1 1 1 0 Velvet factor Fmp27 PF10344.4 CDJ67240.1 - 1.3 6.6 7.4 1.6 6.3 5.1 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 WLM PF08325.5 CDJ67240.1 - 1.3 8.8 8.8 1.7 8.4 6.1 1.2 1 0 0 1 1 1 0 WLM domain Sporozoite_P67 PF05642.6 CDJ67240.1 - 2.4 5.9 13.5 2.7 5.7 9.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Draxin PF15550.1 CDJ67240.1 - 2.5 7.6 10.6 3 7.4 7.3 1.1 1 0 0 1 1 1 0 Draxin CDC73 PF05179.9 CDJ67240.1 - 2.5 7.3 9.9 2.9 7.1 6.9 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family BAF1_ABF1 PF04684.8 CDJ67240.1 - 2.6 6.7 31.6 3.5 6.3 21.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BTV_NS2 PF04514.7 CDJ67240.1 - 2.6 6.8 6.8 2.8 6.7 4.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1675 PF07897.6 CDJ67240.1 - 2.7 7.7 12.0 3.2 7.5 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2052 PF09747.4 CDJ67240.1 - 3 7.7 14.4 4.1 7.2 10.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Macoilin PF09726.4 CDJ67240.1 - 4 5.6 12.5 4.5 5.4 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF966 PF06136.8 CDJ67240.1 - 4.3 6.6 15.7 4.9 6.4 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2217 PF10265.4 CDJ67240.1 - 4.4 5.9 8.0 5.2 5.7 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FAM60A PF15396.1 CDJ67240.1 - 4.7 6.9 10.0 5.6 6.6 7.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF1510 PF07423.6 CDJ67240.1 - 6.5 6.0 12.5 8.1 5.7 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pro_isomerase PF00160.16 CDJ67241.1 - 5.9e-08 33.0 0.0 7.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mut7-C PF01927.11 CDJ67242.1 - 0.058 13.3 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Mut7-C RNAse domain FAM60A PF15396.1 CDJ67242.1 - 0.57 9.8 3.3 0.94 9.1 2.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TraV PF09676.5 CDJ67242.1 - 1.7 9.3 7.2 0.86 10.3 2.3 2.3 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) CDK5_activator PF03261.10 CDJ67242.1 - 1.9 7.7 6.4 3 7.0 4.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DDHD PF02862.12 CDJ67242.1 - 3.3 7.4 5.9 5.3 6.7 4.1 1.2 1 0 0 1 1 1 0 DDHD domain DUF572 PF04502.8 CDJ67242.1 - 7.6 5.6 15.1 13 4.8 10.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DSHCT PF08148.7 CDJ67244.1 - 5.3e-49 165.8 4.1 3.7e-29 101.2 0.1 2.5 1 1 2 3 3 3 2 DSHCT (NUC185) domain PG_binding_2 PF08823.6 CDJ67244.1 - 0.049 13.7 0.0 13 5.9 0.0 3.0 3 0 0 3 3 3 0 Putative peptidoglycan binding domain DUF4131 PF13567.1 CDJ67244.1 - 0.053 12.9 9.0 1 8.7 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_60s PF00428.14 CDJ67244.1 - 2.3 8.6 13.9 0.066 13.6 4.8 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_transf_5 PF08323.6 CDJ67245.1 - 2.9e-15 56.4 0.1 3.5e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 Starch synthase catalytic domain rve PF00665.21 CDJ67247.1 - 3.6e-20 72.2 0.0 8.5e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDJ67247.1 - 1.9e-09 37.0 0.1 3.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDJ67247.1 - 0.00034 20.0 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 CDJ67247.1 - 0.011 15.0 0.3 0.023 14.0 0.2 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Presenilin PF01080.12 CDJ67248.1 - 1.2 7.8 7.3 1.4 7.7 5.0 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_S15 PF02129.13 CDJ67248.1 - 1.6 8.0 7.9 1.9 7.8 5.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Nop53 PF07767.6 CDJ67248.1 - 3.1 6.6 17.0 4.5 6.1 11.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MSP1_C PF07462.6 CDJ67248.1 - 3.4 5.9 9.0 3.6 5.8 6.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Solute_trans_a PF03619.11 CDJ67249.1 - 4.7e-28 98.2 0.0 5.8e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha E2_bind PF08825.5 CDJ67249.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 E2 binding domain NUDIX PF00293.23 CDJ67250.1 - 3.1e-19 68.9 0.0 5.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SR-25 PF10500.4 CDJ67250.1 - 0.0054 16.2 18.5 0.0054 16.2 12.9 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.11 CDJ67250.1 - 0.0055 16.6 18.1 0.0071 16.2 8.3 2.2 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF3306 PF11748.3 CDJ67250.1 - 0.064 13.9 0.5 0.064 13.9 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Peptidase_S15 PF02129.13 CDJ67250.1 - 0.32 10.3 20.0 0.053 12.9 0.2 3.1 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Suf PF05843.9 CDJ67250.1 - 0.6 9.7 43.6 0.81 9.3 5.7 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ67250.1 - 0.82 8.6 52.3 0.36 9.8 9.0 3.1 3 0 0 3 3 3 0 Fms-interacting protein AAA_23 PF13476.1 CDJ67250.1 - 0.91 9.8 35.8 0.49 10.6 5.4 3.1 3 0 0 3 3 3 0 AAA domain RIC3 PF15361.1 CDJ67250.1 - 1 9.6 25.4 2.5 8.3 1.4 3.3 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 Raftlin PF15250.1 CDJ67250.1 - 2 6.8 27.8 1.3 7.4 7.6 3.0 3 0 0 3 3 3 0 Raftlin DUF4557 PF15101.1 CDJ67250.1 - 2.3 8.0 52.3 0.03 14.1 5.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) EPL1 PF10513.4 CDJ67250.1 - 2.5 8.3 26.9 4.3 7.5 2.2 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like CPSF100_C PF13299.1 CDJ67250.1 - 2.7 8.1 22.8 3.3 7.8 1.7 3.2 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal PRP3 PF08572.5 CDJ67250.1 - 3.2 7.0 36.3 0.25 10.7 2.8 3.3 3 0 0 3 3 3 0 pre-mRNA processing factor 3 (PRP3) DUF2217 PF10265.4 CDJ67250.1 - 3.7 6.1 22.5 0.41 9.3 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2217) DUF2076 PF09849.4 CDJ67250.1 - 3.8 7.5 48.3 0.9 9.5 4.4 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) PAT1 PF09770.4 CDJ67250.1 - 4.2 5.4 73.6 0.61 8.2 11.5 3.0 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 PIH1 PF08190.7 CDJ67250.1 - 4.8 6.5 36.6 0.16 11.4 2.8 3.1 3 0 0 3 3 3 0 pre-RNA processing PIH1/Nop17 DUF737 PF05300.6 CDJ67250.1 - 6.9 6.5 40.4 0.27 11.1 1.8 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF737) DUF2052 PF09747.4 CDJ67250.1 - 7.1 6.5 35.8 1.6 8.5 5.6 3.1 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Band_3_cyto PF07565.8 CDJ67250.1 - 8.2 5.8 31.1 4.2 6.7 3.9 3.1 3 0 0 3 3 3 0 Band 3 cytoplasmic domain tRNA-synt_1b PF00579.20 CDJ67251.1 - 1.9e-23 83.0 0.0 1.9e-23 83.0 0.0 3.3 2 1 1 3 3 3 1 tRNA synthetases class I (W and Y) SprA-related PF12118.3 CDJ67251.1 - 0.00028 20.2 0.0 0.00028 20.2 0.0 4.2 2 2 0 3 3 3 1 SprA-related family S4 PF01479.20 CDJ67251.1 - 0.0044 16.4 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 S4 domain HEPN PF05168.9 CDJ67252.1 - 0.57 10.0 2.9 8.2 6.3 0.1 3.0 3 0 0 3 3 3 0 HEPN domain GKAP PF03359.8 CDJ67253.1 - 0.014 15.0 5.5 0.018 14.6 3.8 1.0 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein DUF1908 PF08926.6 CDJ67253.1 - 1.5 7.5 9.0 1.6 7.4 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) TFIIA PF03153.8 CDJ67253.1 - 2.3 8.0 7.1 2.4 7.9 4.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.6 CDJ67253.1 - 2.6 8.0 24.8 3.7 7.6 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CytochromB561_N PF09786.4 CDJ67253.1 - 2.7 6.3 12.8 2.9 6.2 8.9 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal CAF-1_p150 PF11600.3 CDJ67253.1 - 3.6 6.8 16.0 0.33 10.3 5.1 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 CDJ67253.1 - 3.7 5.7 12.6 4.1 5.5 8.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Pap_E4 PF02711.9 CDJ67253.1 - 5.5 7.8 6.7 13 6.6 4.6 1.7 1 1 0 1 1 1 0 E4 protein CDC27 PF09507.5 CDJ67253.1 - 7 5.7 12.3 8.1 5.5 8.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF566 PF04484.7 CDJ67253.1 - 8.9 5.7 16.6 10 5.4 11.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DNA_pol_viral_N PF00242.12 CDJ67253.1 - 9.1 5.1 10.2 9.6 5.1 7.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF1675 PF07897.6 CDJ67255.1 - 0.091 12.6 1.8 0.22 11.3 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TatC PF00902.13 CDJ67255.1 - 0.29 10.4 1.8 0.47 9.8 1.2 1.2 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) GatB_N PF02934.10 CDJ67256.1 - 3.9e-73 245.8 0.0 2.3e-67 226.9 0.0 2.4 1 1 1 2 2 2 2 GatB/GatE catalytic domain DEC-1_N PF04625.8 CDJ67256.1 - 4.1 5.9 18.4 1.1 7.8 10.0 1.8 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PWI PF01480.12 CDJ67257.1 - 0.031 14.3 0.3 0.22 11.6 0.1 2.3 1 1 1 2 2 2 0 PWI domain Pro_racemase PF05544.6 CDJ67257.1 - 0.073 11.8 1.0 0.12 11.2 0.5 1.4 1 1 0 1 1 1 0 Proline racemase Ribosomal_60s PF00428.14 CDJ67257.1 - 0.44 10.9 15.9 4.9 7.6 0.3 3.4 2 1 0 3 3 3 0 60s Acidic ribosomal protein CAF-1_p150 PF11600.3 CDJ67257.1 - 4.4 6.6 23.9 0.025 13.9 7.3 2.8 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mem_trans PF03547.13 CDJ67257.1 - 8.2 4.5 5.6 5.2 5.2 2.7 1.6 1 1 1 2 2 2 0 Membrane transport protein Dynamin_N PF00350.18 CDJ67258.1 - 1.8e-21 76.7 0.0 6.6e-21 74.8 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CDJ67258.1 - 1.7e-09 37.6 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_4 PF12763.2 CDJ67258.1 - 2.7e-08 33.4 0.0 6.5e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand GTP_EFTU PF00009.22 CDJ67258.1 - 1.3e-05 24.7 0.0 0.00013 21.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CDJ67258.1 - 0.00074 20.0 0.0 0.0066 16.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 CDJ67258.1 - 0.0053 16.7 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CDJ67258.1 - 0.01 15.3 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 CDJ67258.1 - 0.021 13.9 0.0 0.063 12.4 0.0 1.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CDJ67258.1 - 0.078 13.1 0.0 0.39 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 CDJ67258.1 - 0.11 11.8 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CDJ67258.1 - 0.13 11.7 0.0 0.76 9.2 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Cpn60_TCP1 PF00118.19 CDJ67259.1 - 6.2e-33 114.1 2.3 6.8e-33 114.0 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FAD-SLDH PF12318.3 CDJ67259.1 - 0.03 14.0 1.0 0.035 13.8 0.7 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase NifU_N PF01592.11 CDJ67259.1 - 0.05 13.5 2.1 0.075 12.9 1.5 1.4 1 0 0 1 1 1 0 NifU-like N terminal domain Suf PF05843.9 CDJ67260.1 - 0.78 9.4 3.6 0.8 9.3 2.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PHD_3 PF13922.1 CDJ67260.1 - 3.4 7.9 5.2 5.4 7.3 3.6 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Trypan_PARP PF05887.6 CDJ67260.1 - 9.7 6.0 13.5 14 5.4 9.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_60s PF00428.14 CDJ67262.1 - 0.41 11.0 16.8 1 9.7 11.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4175 PF13779.1 CDJ67263.1 - 0.063 10.9 38.5 0.12 10.0 26.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AAA_23 PF13476.1 CDJ67263.1 - 0.46 10.7 13.5 0.69 10.2 9.3 1.2 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 CDJ67264.1 - 9.6e-10 37.6 4.4 1.1e-09 37.4 3.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDJ67264.1 - 1.3e-07 30.7 20.9 1.8e-07 30.2 14.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RRM_1 PF00076.17 CDJ67265.1 - 2.1e-13 49.7 0.0 4.9e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ67265.1 - 2.4e-10 40.2 0.0 5.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ67265.1 - 2e-05 24.3 0.0 6.1e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 CDJ67265.1 - 0.00017 21.1 7.5 0.00017 21.1 5.2 4.3 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein MRP-L27 PF09809.4 CDJ67266.1 - 1.4e-11 44.0 0.0 1.6e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 PRP4 PF08799.6 CDJ67267.1 - 3e-11 42.3 0.5 3e-11 42.3 0.3 2.5 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like MIP-T3 PF10243.4 CDJ67268.1 - 7.3e-05 21.4 51.6 7.3e-05 21.4 35.7 2.6 2 2 0 2 2 2 1 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 CDJ67268.1 - 8.1e-05 22.1 0.8 8.1e-05 22.1 0.6 4.0 5 0 0 5 5 5 1 Spore coat protein CotO Zip PF02535.17 CDJ67268.1 - 9e-05 21.6 1.0 9e-05 21.6 0.7 4.1 3 1 1 4 4 4 2 ZIP Zinc transporter GMC_oxred_C PF05199.8 CDJ67268.1 - 0.00027 21.2 0.0 0.00027 21.2 0.0 3.2 4 0 0 4 4 4 1 GMC oxidoreductase SAPS PF04499.10 CDJ67268.1 - 0.0012 17.6 0.0 0.0012 17.6 0.0 3.3 2 1 0 3 3 3 1 SIT4 phosphatase-associated protein GRP PF07172.6 CDJ67268.1 - 0.022 15.1 6.5 0.022 15.1 4.5 4.9 3 1 0 3 3 3 0 Glycine rich protein family NARP1 PF12569.3 CDJ67268.1 - 1.9 7.1 42.6 1.5 7.4 17.7 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 GMC_oxred_N PF00732.14 CDJ67269.1 - 3.7e-21 75.5 3.0 1.1e-13 51.0 0.0 3.4 1 1 1 3 3 3 3 GMC oxidoreductase Suf PF05843.9 CDJ67269.1 - 1.2 8.8 30.4 0.081 12.6 3.7 3.2 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 CDJ67269.1 - 6.8 6.5 15.1 2.2 8.0 0.9 3.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.1 CDJ67269.1 - 8.3 6.6 19.9 3.7 7.8 2.6 2.4 2 0 0 2 2 2 0 AAA domain DUF755 PF05501.6 CDJ67270.1 - 0.88 9.6 7.7 1.4 9.0 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 CDJ67270.1 - 4.7 6.6 15.4 10 5.5 10.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RdRP_1 PF00680.15 CDJ67272.1 - 1.9e-23 82.5 0.0 2.3e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP_4 PF02123.11 CDJ67272.1 - 9.3e-12 44.4 0.0 9.9e-12 44.3 0.0 1.0 1 0 0 1 1 1 1 Viral RNA-directed RNA-polymerase Actin PF00022.14 CDJ67273.1 - 0.0011 17.5 0.0 0.11 10.8 0.0 2.0 2 0 0 2 2 2 2 Actin FAM220 PF15487.1 CDJ67273.1 - 0.49 9.7 8.7 0.65 9.3 6.0 1.1 1 0 0 1 1 1 0 FAM220 family SR-25 PF10500.4 CDJ67273.1 - 0.93 8.9 15.7 1.3 8.4 10.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1908 PF08926.6 CDJ67273.1 - 4.5 5.9 7.7 5.9 5.5 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Parvo_coat PF00740.13 CDJ67275.1 - 4.6 6.0 22.8 5.7 5.7 15.8 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PAT1 PF09770.4 CDJ67275.1 - 5.4 5.1 43.4 6.3 4.8 30.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ant_C PF05586.6 CDJ67275.1 - 5.5 7.5 9.8 22 5.5 0.1 2.3 2 0 0 2 2 2 0 Anthrax receptor C-terminus region PAS PF00989.19 CDJ67275.1 - 8.9 6.1 7.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 PAS fold Hamartin PF04388.7 CDJ67275.1 - 9 4.8 17.8 11 4.5 12.3 1.0 1 0 0 1 1 1 0 Hamartin protein Chorion_2 PF03964.10 CDJ67275.1 - 9.6 6.8 26.7 1.5e+04 -6.3 18.5 2.3 1 1 0 1 1 1 0 Chorion family 2 Cmyb_C PF09316.5 CDJ67277.1 - 0.039 13.6 0.9 0.039 13.6 0.6 1.5 2 0 0 2 2 2 0 C-myb, C-terminal DUF1631 PF07793.6 CDJ67277.1 - 7.7 4.5 16.4 11 4.0 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Proteasome PF00227.21 CDJ67279.1 - 6e-33 113.7 0.1 1.2e-32 112.7 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Med15 PF09606.5 CDJ67279.1 - 0.043 12.0 42.5 0.069 11.3 29.5 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ67279.1 - 0.55 8.4 49.7 0.75 7.9 34.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_18 PF13238.1 CDJ67280.1 - 2.2e-19 70.0 0.0 2.9e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDJ67280.1 - 8.4e-14 52.4 0.0 9.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDJ67280.1 - 3.8e-06 27.0 1.1 0.00021 21.3 0.8 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CDJ67280.1 - 1.8e-05 24.6 0.2 0.00015 21.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 CDJ67280.1 - 0.00026 20.9 0.0 0.0053 16.6 0.0 2.2 2 1 0 2 2 2 1 Adenylate kinase SKI PF01202.17 CDJ67280.1 - 0.00041 20.2 0.0 0.096 12.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_22 PF13401.1 CDJ67280.1 - 0.00043 20.4 0.0 0.00068 19.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CDJ67280.1 - 0.00074 19.7 0.0 0.002 18.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CDJ67280.1 - 0.0012 18.7 0.0 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 CDJ67280.1 - 0.002 17.3 0.0 0.0046 16.1 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 CDJ67280.1 - 0.0039 17.0 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CDJ67280.1 - 0.0078 16.3 0.0 0.016 15.3 0.0 1.5 2 0 0 2 2 1 1 RNA helicase AAA_19 PF13245.1 CDJ67280.1 - 0.0078 15.9 0.0 0.089 12.5 0.0 2.2 2 1 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 CDJ67280.1 - 0.0079 15.6 0.2 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain IstB_IS21 PF01695.12 CDJ67280.1 - 0.0092 15.4 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.10 CDJ67280.1 - 0.0096 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 NTPase NACHT PF05729.7 CDJ67280.1 - 0.011 15.4 0.1 0.052 13.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 CDJ67280.1 - 0.015 14.7 0.1 0.063 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CDJ67280.1 - 0.02 13.8 0.0 0.041 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FliS PF02561.9 CDJ67280.1 - 0.027 14.3 0.1 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 Flagellar protein FliS KAP_NTPase PF07693.9 CDJ67280.1 - 0.028 13.4 0.0 0.055 12.4 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain RuvB_N PF05496.7 CDJ67280.1 - 0.034 13.1 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 CDJ67280.1 - 0.042 12.6 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 CDJ67280.1 - 0.043 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 CDJ67280.1 - 0.056 13.1 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CDJ67280.1 - 0.058 12.9 0.1 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF258 PF03193.11 CDJ67280.1 - 0.064 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 CDJ67280.1 - 0.072 12.0 0.0 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 CDJ67280.1 - 0.092 12.2 0.1 0.87 9.0 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Miro PF08477.8 CDJ67280.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ArsA_ATPase PF02374.10 CDJ67280.1 - 0.1 11.5 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase MMR_HSR1 PF01926.18 CDJ67280.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SpecificRecomb PF10136.4 CDJ67280.1 - 0.11 10.5 0.1 0.14 10.1 0.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase Phostensin_N PF13916.1 CDJ67282.1 - 0.49 10.4 2.7 9.1 6.3 0.4 2.2 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal TALPID3 PF15324.1 CDJ67282.1 - 0.69 7.1 4.7 0.73 7.0 3.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Ribosomal_60s PF00428.14 CDJ67282.1 - 0.73 10.2 14.4 1.1 9.7 9.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3123 PF11321.3 CDJ67282.1 - 0.89 9.8 4.6 1.1 9.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) WD40 PF00400.27 CDJ67283.1 - 1e-09 37.9 0.1 0.0011 18.7 0.0 3.8 3 1 0 3 3 3 3 WD domain, G-beta repeat Sof1 PF04158.9 CDJ67283.1 - 1.6e-09 37.6 24.3 1.1e-08 35.0 15.9 2.2 1 1 1 2 2 2 1 Sof1-like domain BBS2_C PF14782.1 CDJ67283.1 - 0.00067 18.3 6.8 0.00093 17.8 4.7 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal DUF4628 PF15429.1 CDJ67283.1 - 0.21 11.0 9.0 0.32 10.3 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Spt20 PF12090.3 CDJ67283.1 - 0.9 8.8 11.5 0.03 13.6 3.8 1.6 2 0 0 2 2 2 0 Spt20 family Gag_spuma PF03276.9 CDJ67283.1 - 1.8 6.8 20.2 3.1 6.0 14.0 1.4 1 0 0 1 1 1 0 Spumavirus gag protein Presenilin PF01080.12 CDJ67283.1 - 5.3 5.7 5.5 6.8 5.3 3.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.1 CDJ67283.1 - 9.8 3.7 32.1 16 3.0 22.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hid1 PF12722.2 CDJ67284.1 - 3.8e-69 233.3 0.1 5.2e-53 180.0 0.0 6.1 3 2 3 6 6 6 5 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CDJ67284.1 - 5.4e-66 223.1 6.2 8.5e-61 205.9 0.0 3.6 1 1 1 3 3 3 3 Dyggve-Melchior-Clausen syndrome protein Cwf_Cwc_15 PF04889.7 CDJ67284.1 - 0.0077 15.9 5.7 0.0077 15.9 3.9 3.1 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein LMBR1 PF04791.11 CDJ67284.1 - 2.3 6.7 10.9 0.38 9.2 1.7 2.4 2 0 0 2 2 2 0 LMBR1-like membrane protein SAPS PF04499.10 CDJ67284.1 - 8.2 4.9 30.7 0.024 13.2 9.3 2.7 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein DUF3918 PF13056.1 CDJ67285.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Mpp10 PF04006.7 CDJ67286.1 - 0.0047 15.3 14.6 0.0054 15.1 10.1 1.0 1 0 0 1 1 1 1 Mpp10 protein CAF-1_p150 PF11600.3 CDJ67286.1 - 0.029 13.7 20.2 0.037 13.4 14.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDJ67286.1 - 0.2 9.8 51.4 0.23 9.6 35.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dsh_C PF12316.3 CDJ67286.1 - 0.42 10.6 18.5 0.53 10.3 12.8 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4569 PF15133.1 CDJ67286.1 - 0.45 9.8 17.1 0.53 9.6 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) GAGA_bind PF06217.7 CDJ67286.1 - 0.81 9.5 17.1 0.92 9.4 11.8 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Corona_nucleoca PF00937.13 CDJ67286.1 - 1.6 7.6 21.7 1.7 7.5 15.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2126 PF09899.4 CDJ67286.1 - 1.7 6.5 9.9 2 6.3 6.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) eIF-3_zeta PF05091.7 CDJ67286.1 - 2.4 6.6 19.1 2.8 6.4 13.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDJ67286.1 - 2.5 6.2 40.1 3.1 5.9 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MSP1_C PF07462.6 CDJ67286.1 - 2.7 6.2 15.7 3.1 6.0 10.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SAGA-Tad1 PF12767.2 CDJ67286.1 - 2.8 7.5 23.7 3.4 7.2 16.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Isy1 PF06246.7 CDJ67286.1 - 3.5 6.9 20.0 4.9 6.4 13.8 1.1 1 0 0 1 1 1 0 Isy1-like splicing family SOBP PF15279.1 CDJ67286.1 - 5.4 7.3 16.4 6.4 7.0 11.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein BTV_NS2 PF04514.7 CDJ67286.1 - 6.6 5.5 16.9 8.3 5.1 11.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SR-25 PF10500.4 CDJ67286.1 - 7 6.0 28.9 0.56 9.6 7.0 1.9 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Ank_5 PF13857.1 CDJ67287.1 - 0.015 15.5 0.1 6.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Resolvase PF00239.16 CDJ67287.1 - 0.15 11.9 0.9 0.26 11.1 0.6 1.3 1 0 0 1 1 1 0 Resolvase, N terminal domain Pkinase PF00069.20 CDJ67288.1 - 1.5e-31 109.5 0.0 3.8e-31 108.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67288.1 - 5.5e-17 61.6 0.0 4.4e-15 55.4 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Collagen PF01391.13 CDJ67288.1 - 3.1e-05 23.4 17.0 9.1e-05 21.9 11.8 1.8 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Kinase-like PF14531.1 CDJ67288.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribosomal_S21e PF01249.13 CDJ67290.1 - 2e-19 69.3 0.0 2.5e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e OEP PF02321.13 CDJ67291.1 - 0.32 10.5 10.9 0.016 14.7 2.5 1.9 2 0 0 2 2 2 0 Outer membrane efflux protein OMP_b-brl PF13505.1 CDJ67291.1 - 1.3 8.9 9.9 1.7 8.5 0.4 2.2 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain TSP9 PF11493.3 CDJ67291.1 - 4.5 7.8 6.1 5.3 7.6 0.3 2.5 3 0 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 Ribosomal_60s PF00428.14 CDJ67291.1 - 5.8 7.3 32.7 0.51 10.7 4.6 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein HdeA PF06411.6 CDJ67291.1 - 5.9 6.9 9.0 3.2 7.7 0.8 2.3 2 0 0 2 2 2 0 HdeA/HdeB family DUF2201_N PF13203.1 CDJ67292.1 - 0.00014 21.1 7.7 0.00025 20.3 5.3 1.3 1 0 0 1 1 1 1 Putative metallopeptidase domain SGT1 PF07093.6 CDJ67292.1 - 0.0055 15.1 13.9 0.0085 14.5 9.7 1.2 1 0 0 1 1 1 1 SGT1 protein DUF2076 PF09849.4 CDJ67292.1 - 0.015 15.3 20.4 0.12 12.4 11.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) CDC37_N PF03234.9 CDJ67292.1 - 0.033 14.4 10.1 0.028 14.7 4.6 2.3 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding PAT1 PF09770.4 CDJ67292.1 - 0.082 11.1 26.8 0.11 10.7 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 CDJ67292.1 - 0.16 10.9 0.6 0.24 10.3 0.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Med15 PF09606.5 CDJ67292.1 - 0.62 8.1 37.5 1 7.5 26.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 CDJ67292.1 - 3.4 7.4 9.8 1.3 8.8 5.0 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Het-C PF07217.6 CDJ67292.1 - 3.9 5.5 11.5 6.6 4.7 8.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C BTV_NS2 PF04514.7 CDJ67292.1 - 7.9 5.2 13.1 13 4.4 9.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 tRNA_synt_1c_R2 PF04557.10 CDJ67292.1 - 9.6 6.9 9.8 1.9 9.2 2.1 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Plasmodium_Vir PF05795.6 CDJ67294.1 - 0.027 13.6 0.1 1.7 7.7 0.0 2.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Med15 PF09606.5 CDJ67294.1 - 0.42 8.7 49.8 0.034 12.3 17.8 2.0 1 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ67294.1 - 6.9 4.7 30.9 9.6 4.3 21.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THRAP3_BCLAF1 PF15440.1 CDJ67294.1 - 7.6 5.0 24.2 10 4.6 16.8 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family KAR9 PF08580.5 CDJ67294.1 - 9.9 4.2 15.0 12 4.0 10.4 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Pkinase PF00069.20 CDJ67295.1 - 2.6e-51 174.2 1.5 1.1e-49 168.8 0.2 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67295.1 - 1.9e-19 69.7 0.0 4.4e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CDJ67295.1 - 2.2e-05 24.3 7.7 0.0006 19.6 5.4 2.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family CDK2AP PF09806.4 CDJ67295.1 - 8.7e-05 22.8 6.7 0.00014 22.1 4.7 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Corona_nucleoca PF00937.13 CDJ67295.1 - 0.0019 17.1 5.3 0.0026 16.7 3.7 1.1 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein Kdo PF06293.9 CDJ67295.1 - 0.0024 16.9 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDJ67295.1 - 0.0027 17.0 0.9 0.008 15.5 0.4 1.9 2 1 0 2 2 2 1 RIO1 family CAF-1_p150 PF11600.3 CDJ67295.1 - 0.0074 15.6 8.4 0.011 15.1 5.8 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Choline_kinase PF01633.15 CDJ67295.1 - 0.015 14.8 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 CDJ67295.1 - 0.026 13.4 0.0 0.052 12.5 0.0 1.6 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 CDJ67295.1 - 0.029 13.6 0.3 0.54 9.5 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Suf PF05843.9 CDJ67295.1 - 0.065 12.9 1.3 0.11 12.2 0.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1675 PF07897.6 CDJ67295.1 - 0.17 11.7 6.0 0.24 11.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4614 PF15391.1 CDJ67295.1 - 0.35 10.6 8.1 0.59 9.8 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Spt20 PF12090.3 CDJ67295.1 - 0.54 9.5 3.2 0.23 10.7 0.2 1.9 3 0 0 3 3 3 0 Spt20 family DUF2201_N PF13203.1 CDJ67295.1 - 1 8.4 9.5 1.5 7.8 6.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Macoilin PF09726.4 CDJ67295.1 - 4.2 5.5 7.8 5.9 5.0 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 CDJ67295.1 - 7.8 4.4 8.0 11 3.9 5.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HTH_Tnp_IS1 PF12759.2 CDJ67296.1 - 0.36 10.2 3.7 0.23 10.8 0.3 2.2 2 1 0 2 2 2 0 InsA C-terminal domain BRCT PF00533.21 CDJ67297.1 - 5.9e-05 23.1 0.0 0.00052 20.1 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Med15 PF09606.5 CDJ67298.1 - 0.00015 20.1 112.6 0.00015 20.1 78.0 2.4 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ67299.1 - 0.074 13.4 10.6 0.082 13.3 7.3 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein RskA PF10099.4 CDJ67299.1 - 0.79 9.4 6.3 0.81 9.4 4.4 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Chorion_2 PF03964.10 CDJ67299.1 - 1.3 9.6 9.5 1.5 9.4 6.6 1.2 1 0 0 1 1 1 0 Chorion family 2 Shadoo PF14999.1 CDJ67299.1 - 1.9 8.3 10.4 2 8.2 7.2 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF2188 PF09954.4 CDJ67299.1 - 2.5 8.0 4.8 3 7.8 3.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) CDK2AP PF09806.4 CDJ67299.1 - 7.1 6.8 8.3 7.2 6.7 5.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein zf-RING_UBOX PF13445.1 CDJ67300.1 - 5.1e-06 26.1 6.2 1.6e-05 24.4 4.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CDJ67300.1 - 0.00014 21.4 8.8 0.00014 21.4 6.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDJ67300.1 - 0.0002 21.1 9.1 0.0002 21.1 6.3 2.6 3 0 0 3 3 3 1 Ring finger domain SR-25 PF10500.4 CDJ67300.1 - 0.00038 20.0 9.7 0.00038 20.0 6.7 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein zf-C3HC4 PF00097.20 CDJ67300.1 - 0.0032 17.1 8.3 0.0032 17.1 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ67300.1 - 0.016 15.2 9.9 0.016 15.2 6.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDJ67300.1 - 0.032 14.1 9.6 0.032 14.1 6.6 3.0 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Sporozoite_P67 PF05642.6 CDJ67300.1 - 9.7 3.9 9.7 17 3.1 6.7 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen N6_N4_Mtase PF01555.13 CDJ67303.1 - 0.0003 20.3 0.0 24 4.3 0.0 3.4 3 1 0 3 3 3 2 DNA methylase DUF2454 PF10521.4 CDJ67304.1 - 0.05 12.5 0.3 0.05 12.5 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2454) SR-25 PF10500.4 CDJ67304.1 - 0.16 11.3 60.2 0.014 14.8 6.6 4.6 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein VSG_B PF13206.1 CDJ67305.1 - 0.33 10.0 4.6 0.31 10.1 2.8 1.3 1 1 0 1 1 1 0 Trypanosomal VSG domain DASH_Dad2 PF08654.5 CDJ67306.1 - 0.12 12.4 1.6 5.3 7.0 0.0 2.3 1 1 0 2 2 2 0 DASH complex subunit Dad2 DUF3142 PF11340.3 CDJ67306.1 - 0.12 12.0 1.8 0.28 10.8 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3142) RRM_1 PF00076.17 CDJ67307.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GAGA_bind PF06217.7 CDJ67308.1 - 5.2 6.9 21.7 6.7 6.5 15.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Maf1 PF09174.5 CDJ67308.1 - 9.4 6.0 9.2 2 8.2 0.4 2.3 2 0 0 2 2 2 0 Maf1 regulator Nucleoporin2 PF04096.9 CDJ67309.1 - 7.7e-35 119.7 0.0 7.7e-35 119.7 0.0 3.6 3 0 0 3 3 3 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CDJ67309.1 - 6.6e-24 84.3 378.2 3.9e-08 33.5 35.4 25.3 11 5 9 20 20 20 8 Nucleoporin FG repeat region Sushi PF00084.15 CDJ67310.1 - 4.5e-06 26.9 0.0 8.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Sushi domain (SCR repeat) SR-25 PF10500.4 CDJ67310.1 - 0.0046 16.4 11.4 0.0046 16.4 7.9 5.2 5 0 0 5 5 5 3 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ67311.1 - 3.1e-08 33.3 19.4 3.3e-08 33.2 13.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 CDJ67311.1 - 0.003 17.3 12.1 0.0039 16.9 8.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Apt1 PF10351.4 CDJ67311.1 - 0.052 12.3 12.7 0.055 12.3 8.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.1 CDJ67311.1 - 0.053 13.2 8.5 0.06 13.1 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Nucleo_P87 PF07267.6 CDJ67311.1 - 0.27 9.8 9.2 0.27 9.8 6.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FancD2 PF14631.1 CDJ67311.1 - 0.29 8.1 7.0 0.29 8.1 4.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF4603 PF15376.1 CDJ67311.1 - 0.42 7.7 10.7 0.43 7.6 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Presenilin PF01080.12 CDJ67311.1 - 0.59 8.9 5.3 0.6 8.8 3.7 1.1 1 0 0 1 1 1 0 Presenilin Pox_A12 PF04651.8 CDJ67311.1 - 0.71 9.9 8.3 0.98 9.5 5.7 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein POX PF07526.6 CDJ67311.1 - 0.97 9.6 7.2 1.3 9.3 5.0 1.3 1 1 0 1 1 1 0 Associated with HOX DUF3548 PF12068.3 CDJ67311.1 - 1.2 8.3 6.5 1.5 8.0 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) NAM-associated PF14303.1 CDJ67311.1 - 1.3 9.3 9.5 1.5 9.1 6.6 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain FDF PF09532.5 CDJ67311.1 - 2.3 8.8 8.7 3.3 8.2 6.0 1.4 1 1 0 1 1 1 0 FDF domain DUF4602 PF15375.1 CDJ67311.1 - 2.3 8.2 11.3 3.5 7.7 7.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) DUF3827 PF12877.2 CDJ67311.1 - 3.3 5.6 9.9 3.5 5.5 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4544 PF15077.1 CDJ67311.1 - 3.4 7.1 6.3 3.6 7.0 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) CDC45 PF02724.9 CDJ67311.1 - 5.3 4.9 14.5 6.3 4.6 10.0 1.0 1 0 0 1 1 1 0 CDC45-like protein polyprenyl_synt PF00348.12 CDJ67312.1 - 4.2e-43 147.0 0.0 6.9e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.20 CDJ67313.1 - 1.3e-11 44.1 0.1 1.6e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67313.1 - 0.00089 18.4 0.0 0.018 14.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RVT_1 PF00078.22 CDJ67315.1 - 0.002 17.5 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.3 CDJ67315.1 - 0.091 11.9 1.1 0.13 11.4 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Rft-1 PF04506.8 CDJ67317.1 - 2.1e-12 46.2 0.5 3.4e-07 29.0 0.1 2.1 2 0 0 2 2 2 2 Rft protein Sad1_UNC PF07738.8 CDJ67318.1 - 3.9e-15 55.8 0.0 1.3e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Med5 PF08689.5 CDJ67318.1 - 9.6 3.7 8.5 20 2.6 5.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit Med5 Methyltransf_23 PF13489.1 CDJ67319.1 - 0.0049 16.5 0.0 0.0068 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Lep_receptor_Ig PF06328.6 CDJ67319.1 - 0.014 15.2 0.3 0.04 13.7 0.2 1.8 1 1 1 2 2 2 0 Ig-like C2-type domain SNF2_N PF00176.18 CDJ67320.1 - 9.5e-78 261.0 0.0 2.3e-77 259.7 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDJ67320.1 - 6.9e-14 51.4 0.0 6.9e-14 51.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CDJ67320.1 - 1.5e-13 50.2 0.7 1.5e-13 50.2 0.5 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CDJ67320.1 - 3.6e-05 23.3 0.0 0.00014 21.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase BAF1_ABF1 PF04684.8 CDJ67322.1 - 0.0021 17.0 11.9 0.0021 17.0 8.3 5.3 3 1 1 4 4 4 1 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 CDJ67322.1 - 0.32 10.4 17.7 0.36 10.2 8.7 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein rve PF00665.21 CDJ67323.1 - 1.2e-07 31.8 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Surface_antigen PF11054.3 CDJ67324.1 - 7.2e-106 353.2 2.8 8.3e-106 353.0 1.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3904 PF13044.1 CDJ67328.1 - 0.11 10.8 0.1 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) RNase_H2_suC PF08615.6 CDJ67330.1 - 1.7e-13 50.6 0.0 3.7e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) UPF0016 PF01169.14 CDJ67331.1 - 2.3e-33 114.1 23.1 5.9e-21 74.3 3.0 3.6 4 0 0 4 4 4 3 Uncharacterized protein family UPF0016 DUF4131 PF13567.1 CDJ67331.1 - 0.44 9.9 7.7 0.56 9.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Nop14 PF04147.7 CDJ67333.1 - 0.024 12.5 14.2 0.031 12.2 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family Cyclin_C PF02984.14 CDJ67334.1 - 0.00012 22.0 0.2 0.00012 22.0 0.1 3.7 4 0 0 4 4 4 1 Cyclin, C-terminal domain HEAT PF02985.17 CDJ67335.1 - 2.4e-09 36.5 46.6 0.0018 18.2 0.0 12.4 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.1 CDJ67335.1 - 1.7e-05 24.9 14.2 5.6e-05 23.3 0.9 11.0 7 4 2 9 9 9 3 HEAT repeats DUF3337 PF11816.3 CDJ67335.1 - 0.18 11.1 4.1 41 3.4 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3337) Adaptin_N PF01602.15 CDJ67335.1 - 8.1 4.6 7.8 19 3.3 0.4 3.5 4 0 0 4 4 4 0 Adaptin N terminal region DUF4042 PF13251.1 CDJ67335.1 - 8.4 5.8 15.4 1.7 8.0 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) Exo_endo_phos PF03372.18 CDJ67337.1 - 1.5e-05 25.0 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CDK2AP PF09806.4 CDJ67337.1 - 5.8e-05 23.4 3.2 8.5e-05 22.8 2.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CDJ67337.1 - 0.0027 17.2 10.5 0.0027 17.2 7.3 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 CDJ67337.1 - 0.0041 17.4 0.0 0.014 15.7 0.0 1.8 1 1 0 1 1 1 1 Dehydrin DUF2722 PF10846.3 CDJ67337.1 - 0.02 13.9 5.7 0.054 12.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.3 CDJ67337.1 - 0.2 10.3 21.2 0.63 8.7 13.9 1.9 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDJ67337.1 - 3.1 5.9 15.9 3.6 5.6 11.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ67338.1 - 0.35 9.0 51.2 0.38 8.9 35.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDJ67338.1 - 0.54 10.0 19.4 0.59 9.9 13.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 CDJ67338.1 - 0.87 7.9 36.2 1 7.7 25.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 CDJ67338.1 - 1.5 7.8 23.7 1.8 7.6 16.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Macoilin PF09726.4 CDJ67338.1 - 2 6.6 36.3 2.6 6.2 25.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 CDJ67338.1 - 2.2 7.4 30.0 2.7 7.1 20.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Gag_spuma PF03276.9 CDJ67338.1 - 3.7 5.7 37.8 4.4 5.4 26.2 1.3 1 0 0 1 1 1 0 Spumavirus gag protein Na_trans_assoc PF06512.8 CDJ67338.1 - 6 6.7 20.1 7.4 6.4 14.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated CwfJ_C_2 PF04676.9 CDJ67339.1 - 4.7e-09 36.6 0.0 7.3e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 Protein similar to CwfJ C-terminus 2 SR-25 PF10500.4 CDJ67340.1 - 0.0038 16.7 1.9 0.0038 16.7 1.3 9.4 4 1 3 9 9 9 3 Nuclear RNA-splicing-associated protein HXXEE PF13787.1 CDJ67340.1 - 0.3 11.4 1.1 46 4.4 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif WD40 PF00400.27 CDJ67341.1 - 0.026 14.4 9.7 0.64 10.0 0.1 4.1 3 1 0 3 3 3 0 WD domain, G-beta repeat GAGA_bind PF06217.7 CDJ67342.1 - 1.5 8.7 25.1 0.59 10.0 3.8 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family MRP-S31 PF15433.1 CDJ67342.1 - 3.1 7.1 36.3 0.3 10.4 5.3 2.4 2 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF4613 PF15390.1 CDJ67342.1 - 3.3 5.7 26.8 0.12 10.5 9.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) V_ATPase_I PF01496.14 CDJ67342.1 - 6.1 4.5 16.9 8.4 4.1 11.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_60s PF00428.14 CDJ67344.1 - 0.031 14.6 5.0 0.031 14.6 3.4 3.6 2 1 1 3 3 3 0 60s Acidic ribosomal protein RNA_pol_Rpb1_5 PF04998.12 CDJ67344.1 - 3.8 6.7 8.6 2.8 7.1 3.1 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 ATP-synt_ab PF00006.20 CDJ67345.1 - 7.1e-62 208.6 0.0 1.2e-61 207.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 CDJ67345.1 - 4.4e-20 71.6 3.2 1.5e-19 69.9 2.2 1.9 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 CDJ67345.1 - 5e-18 65.6 0.7 1.5e-17 64.0 0.5 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain RnfC_N PF13375.1 CDJ67345.1 - 0.0024 17.5 0.7 0.014 15.1 0.3 2.2 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain DUF2722 PF10846.3 CDJ67345.1 - 0.005 15.9 1.0 0.37 9.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Med15 PF09606.5 CDJ67345.1 - 0.016 13.4 19.0 0.25 9.5 6.6 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA PF00004.24 CDJ67345.1 - 0.022 14.9 0.3 0.39 10.9 0.1 2.7 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CDJ67345.1 - 0.028 13.2 0.1 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 CDJ67345.1 - 0.03 14.4 0.5 1.6 8.8 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CDJ67345.1 - 0.046 13.1 0.4 0.2 11.0 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CDJ67345.1 - 0.047 13.6 0.0 0.047 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CDJ67345.1 - 0.05 12.7 0.4 0.12 11.4 0.3 1.6 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 CDJ67345.1 - 0.056 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 CDJ67345.1 - 0.092 13.0 1.7 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 CDJ67345.1 - 0.11 12.5 0.2 0.11 12.5 0.1 3.2 2 1 1 3 3 3 0 AAA ATPase domain NACHT PF05729.7 CDJ67345.1 - 0.11 12.1 2.2 0.18 11.4 0.2 2.4 2 1 0 2 2 2 0 NACHT domain Spt20 PF12090.3 CDJ67345.1 - 0.13 11.5 2.9 2.7 7.2 0.2 2.2 2 0 0 2 2 2 0 Spt20 family Arch_ATPase PF01637.13 CDJ67345.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 CDJ67345.1 - 0.16 11.6 0.0 3.3 7.4 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Med15 PF09606.5 CDJ67346.1 - 0.0013 17.0 61.2 0.0013 17.0 42.4 2.0 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Parvo_coat PF00740.13 CDJ67346.1 - 0.1 11.5 27.9 0.16 10.8 19.4 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF4045 PF13254.1 CDJ67346.1 - 2 7.6 28.4 3.9 6.6 19.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ycf1 PF05758.7 CDJ67346.1 - 2.9 5.5 21.9 3.7 5.1 15.2 1.1 1 0 0 1 1 1 0 Ycf1 MIP-T3 PF10243.4 CDJ67346.1 - 3.5 5.9 35.2 5.7 5.2 24.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 CDJ67346.1 - 3.8 5.0 35.6 5.1 4.6 24.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FRG PF08867.6 CDJ67347.1 - 0.38 11.3 3.3 1.5 9.3 2.3 2.0 1 1 0 1 1 1 0 FRG domain ECH PF00378.15 CDJ67348.1 - 4.6e-24 84.8 0.0 5.8e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CDJ67348.1 - 0.12 12.1 0.0 3 7.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 V-ATPase_C PF03223.10 CDJ67349.1 - 1e-68 231.9 0.0 1.2e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit C Ribosomal_60s PF00428.14 CDJ67351.1 - 0.0095 16.3 10.7 0.076 13.4 0.0 2.5 2 0 0 2 2 2 1 60s Acidic ribosomal protein Cellulose_synt PF03552.9 CDJ67351.1 - 0.13 10.5 0.7 0.15 10.3 0.5 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF853 PF05872.7 CDJ67351.1 - 0.16 10.3 1.4 0.18 10.0 1.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Tom37_C PF11801.3 CDJ67351.1 - 0.22 11.3 4.6 0.32 10.8 3.2 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain PBP1_TM PF14812.1 CDJ67351.1 - 0.51 10.6 3.5 0.8 10.0 2.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FimP PF09766.4 CDJ67351.1 - 1.4 7.9 12.2 1.9 7.4 8.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spore_coat_CotO PF14153.1 CDJ67351.1 - 1.4 8.3 7.3 1.8 7.9 5.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Spc7_N PF15402.1 CDJ67351.1 - 7.6 4.4 18.1 9.7 4.0 12.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 tRNA-synt_1e PF01406.14 CDJ67353.1 - 2.1e-12 46.8 0.0 2.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RskA PF10099.4 CDJ67353.1 - 0.0031 17.2 7.1 0.0038 16.9 4.9 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA CRISPR_Cse2 PF09485.5 CDJ67353.1 - 0.019 15.0 4.3 0.023 14.7 3.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Polysacc_synt_3 PF13440.1 CDJ67353.1 - 0.038 13.4 1.5 0.044 13.2 1.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PepSY_2 PF13670.1 CDJ67353.1 - 0.69 9.8 10.2 1.2 9.1 7.1 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SR-25 PF10500.4 CDJ67353.1 - 1.7 8.0 13.4 1.9 7.8 9.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-NF-X1 PF01422.12 CDJ67354.1 - 0.33 10.9 2.0 0.54 10.2 1.4 1.3 1 0 0 1 1 1 0 NF-X1 type zinc finger CLTH PF10607.4 CDJ67357.1 - 4.1e-22 78.4 0.0 6.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CDJ67357.1 - 1.5e-05 24.6 0.1 2.8e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 LisH BTB PF00651.26 CDJ67359.1 - 6.2e-14 51.9 0.1 1.4e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain HSL_N PF06350.7 CDJ67359.1 - 0.11 11.5 0.3 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus Dus PF01207.12 CDJ67361.1 - 6.7e-46 156.5 0.0 2.6e-38 131.6 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Met_10 PF02475.11 CDJ67363.1 - 1.5e-47 161.7 0.0 1.9e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CDJ67363.1 - 3.7e-06 27.5 0.1 8.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ67363.1 - 1.9e-05 24.6 0.4 1.9e-05 24.6 0.2 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CDJ67363.1 - 0.0031 17.0 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.11 CDJ67363.1 - 0.0036 16.2 0.1 0.0054 15.7 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.10 CDJ67363.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Tetraspannin PF00335.15 CDJ67364.1 - 0.025 13.8 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Tetraspanin family NPV_P10 PF05531.7 CDJ67364.1 - 1.5 9.1 3.4 42 4.4 0.1 3.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3357 PF11837.3 CDJ67365.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DARPP-32 PF05395.7 CDJ67365.1 - 0.069 13.3 0.3 0.069 13.3 0.2 1.6 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Cpn60_TCP1 PF00118.19 CDJ67366.1 - 1.9e-22 79.5 0.0 1.9e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_60s PF00428.14 CDJ67367.1 - 0.86 10.0 9.9 0.18 12.2 0.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Surface_antigen PF11054.3 CDJ67368.1 - 7e-18 64.9 0.1 8.7e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Hydrolase PF00702.21 CDJ67369.1 - 5.4e-11 43.3 4.7 1.3e-07 32.2 0.0 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ67369.1 - 1.1e-10 42.0 0.0 7.6e-10 39.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CDJ67369.1 - 0.028 14.3 0.3 0.21 11.4 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Trp_syntA PF00290.15 CDJ67369.1 - 0.047 12.2 0.0 0.074 11.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain APS_kinase PF01583.15 CDJ67369.1 - 0.051 13.2 0.2 3.4 7.3 0.0 3.1 2 1 0 2 2 2 0 Adenylylsulphate kinase DUF3138 PF11336.3 CDJ67369.1 - 0.53 8.3 7.3 0.7 8.0 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PDEase_I PF00233.14 CDJ67370.1 - 4e-28 98.7 0.2 5e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Dpy19 PF10034.4 CDJ67371.1 - 2.1e-76 257.5 0.0 2.3e-29 102.0 0.0 4.0 1 1 3 4 4 4 4 Q-cell neuroblast polarisation Glyoxalase PF00903.20 CDJ67372.1 - 8.5e-34 116.2 0.0 6.5e-16 58.4 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CDJ67372.1 - 4.4e-30 104.4 0.2 6.2e-16 58.9 0.0 2.4 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CDJ67372.1 - 9.6e-15 54.5 0.0 3e-06 27.2 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CDJ67372.1 - 1.1e-05 25.4 0.0 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 CDJ67372.1 - 0.0091 15.6 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal DUF3081 PF11280.3 CDJ67372.1 - 0.073 12.5 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) CPW_WPC PF09717.5 CDJ67373.1 - 5e-06 27.0 10.6 0.017 15.7 0.3 4.0 4 1 1 5 5 5 3 Plasmodium falciparum domain of unknown function (CPW_WPC) Nodulin_late PF07127.6 CDJ67373.1 - 0.48 10.5 2.9 7.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Late nodulin protein RAP PF08373.5 CDJ67374.1 - 0.0074 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 RAP domain PTPLA PF04387.9 CDJ67375.1 - 3.6e-50 169.5 12.1 3.6e-50 169.5 8.4 1.8 2 1 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA DivIC PF04977.10 CDJ67376.1 - 0.031 13.7 0.8 0.073 12.5 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 CDJ67376.1 - 0.22 11.5 5.6 0.052 13.5 1.0 2.1 2 0 0 2 2 2 0 bZIP transcription factor WD40 PF00400.27 CDJ67378.1 - 1.9e-54 179.6 22.2 3.2e-10 39.4 1.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CDJ67378.1 - 6.5e-09 34.4 3.1 0.009 14.1 0.0 3.8 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CDJ67378.1 - 7.3e-05 21.6 0.2 0.009 14.8 0.0 2.7 2 1 1 3 3 3 2 Nup133 N terminal like Lipase_3 PF01764.20 CDJ67379.1 - 3.1e-15 56.0 0.0 7.6e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CDJ67379.1 - 0.023 14.6 0.3 0.07 12.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family V_ATPase_I PF01496.14 CDJ67380.1 - 0.0031 15.4 15.4 0.0045 14.9 10.7 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Spc7 PF08317.6 CDJ67380.1 - 0.0065 15.1 23.3 0.0081 14.8 16.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DASH_Dam1 PF08653.5 CDJ67380.1 - 0.028 14.1 5.9 1.7 8.4 0.5 2.7 1 1 0 2 2 2 0 DASH complex subunit Dam1 AAA_13 PF13166.1 CDJ67380.1 - 0.17 10.2 9.5 0.25 9.7 6.6 1.3 1 0 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.4 CDJ67380.1 - 0.53 8.6 21.9 0.62 8.4 15.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.6 CDJ67380.1 - 1 9.0 28.6 0.94 9.1 8.1 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FUSC PF04632.7 CDJ67380.1 - 1.7 6.9 23.6 2.2 6.6 16.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bac_GDH PF05088.7 CDJ67380.1 - 2.5 5.3 11.4 3.6 4.8 7.9 1.3 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Mnd1 PF03962.10 CDJ67380.1 - 3.6 7.2 34.9 1.9 8.0 11.7 2.1 1 1 1 2 2 2 0 Mnd1 family CCDC-167 PF15188.1 CDJ67380.1 - 4.4 7.3 6.2 1 9.3 1.5 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Allexi_40kDa PF05549.6 CDJ67380.1 - 4.9 6.3 21.7 1.4 8.1 6.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein AAA_27 PF13514.1 CDJ67380.1 - 5.9 4.4 34.3 7.2 4.1 23.8 1.0 1 0 0 1 1 1 0 AAA domain DUF2730 PF10805.3 CDJ67380.1 - 6.7 6.4 13.8 11 5.7 7.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) GrpE PF01025.14 CDJ67380.1 - 9.4 5.7 20.7 5.2 6.5 5.3 2.2 1 1 1 2 2 2 0 GrpE DUF755 PF05501.6 CDJ67381.1 - 0.01 15.8 14.5 0.012 15.6 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Rotamase_2 PF13145.1 CDJ67381.1 - 0.38 11.4 9.8 0.51 10.9 6.8 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Cwf_Cwc_15 PF04889.7 CDJ67381.1 - 0.54 9.9 2.6 0.62 9.7 1.8 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 CDJ67381.1 - 1.6 8.1 26.1 2.4 7.5 18.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4139 PF13598.1 CDJ67381.1 - 2.3 7.4 11.6 2.4 7.3 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) PAP1 PF08601.5 CDJ67381.1 - 3 7.4 11.8 3.2 7.3 8.2 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 RskA PF10099.4 CDJ67381.1 - 5 6.8 16.0 5.9 6.5 11.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3246 PF11596.3 CDJ67381.1 - 5.2 6.2 11.6 5.9 6.1 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TFIIA PF03153.8 CDJ67381.1 - 7.9 6.2 7.1 8.6 6.1 4.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinesin PF00225.18 CDJ67383.1 - 6.5e-79 265.0 6.2 3.5e-78 262.6 4.3 2.1 1 1 0 1 1 1 1 Kinesin motor domain DUF1216 PF06746.6 CDJ67384.1 - 0.052 13.3 2.3 0.1 12.3 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) Collagen PF01391.13 CDJ67384.1 - 0.065 12.7 36.7 0.075 12.5 22.7 3.2 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) SR-25 PF10500.4 CDJ67384.1 - 0.25 10.7 13.8 0.52 9.7 9.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM220 PF15487.1 CDJ67384.1 - 2.1 7.6 7.5 3 7.1 5.2 1.2 1 0 0 1 1 1 0 FAM220 family DUF755 PF05501.6 CDJ67384.1 - 2.6 8.1 15.8 5 7.2 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Macoilin PF09726.4 CDJ67384.1 - 2.9 6.0 4.4 3.7 5.7 3.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Isy1 PF06246.7 CDJ67385.1 - 2e-32 112.5 6.3 2.5e-32 112.3 4.4 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Phage_Gp23 PF10669.4 CDJ67385.1 - 0.032 14.3 7.0 0.1 12.7 1.3 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Ribosomal_60s PF00428.14 CDJ67385.1 - 0.22 11.9 31.7 0.089 13.2 5.9 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDJ67385.1 - 1.5 6.9 20.3 1.7 6.8 14.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ67385.1 - 2.7 6.0 29.0 3.3 5.7 20.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 CDJ67385.1 - 3.4 5.2 5.1 4.1 4.9 3.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex14_N PF04695.8 CDJ67385.1 - 4 7.4 16.5 1.8 8.6 7.0 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IATP PF04568.7 CDJ67385.1 - 7.2 6.7 15.5 0.32 11.0 1.4 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF3676 PF12429.3 CDJ67385.1 - 7.9 6.0 14.2 11 5.5 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) Asp_protease_2 PF13650.1 CDJ67386.1 - 2.8e-11 43.7 0.0 5.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ67386.1 - 5.1e-09 35.8 0.0 9.7e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ67386.1 - 1.7e-07 31.0 0.0 9.6e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ67386.1 - 3.1e-06 27.1 0.0 5.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ67386.1 - 0.0009 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF3552 PF12072.3 CDJ67386.1 - 0.017 14.3 0.4 0.03 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1758 PF05585.7 CDJ67386.1 - 0.045 13.3 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-CCHC PF00098.18 CDJ67387.1 - 1.1e-07 31.3 12.8 3.7e-06 26.5 1.8 2.4 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.12 CDJ67387.1 - 6.9e-05 22.8 0.3 0.00032 20.7 0.1 2.1 2 1 1 3 3 3 1 Retrotransposon gag protein zf-CCHC_6 PF15288.1 CDJ67387.1 - 0.0029 17.2 0.5 0.0029 17.2 0.4 2.8 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ67387.1 - 0.0032 17.1 0.5 0.0032 17.1 0.4 2.4 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ67387.1 - 0.022 14.4 6.1 0.13 11.9 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ67387.1 - 0.24 11.4 10.8 0.58 10.2 7.5 1.6 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.1 CDJ67387.1 - 2.6 7.6 8.0 0.19 11.2 0.5 2.5 2 1 1 3 3 3 0 Zinc knuckle ETRAMP PF09716.5 CDJ67388.1 - 0.00029 20.7 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Abhydrolase_4 PF08386.5 CDJ67388.1 - 0.045 13.6 1.0 0.045 13.6 0.7 2.8 3 0 0 3 3 3 0 TAP-like protein Ctr PF04145.10 CDJ67388.1 - 0.58 10.2 5.8 0.18 11.8 0.2 2.3 3 0 0 3 3 3 0 Ctr copper transporter family DUF3617 PF12276.3 CDJ67388.1 - 9.4 5.6 13.1 0.46 9.9 2.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3617) TPR_11 PF13414.1 CDJ67391.1 - 5e-09 35.6 6.7 6.4e-07 28.9 0.5 2.8 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.1 CDJ67391.1 - 5.1e-07 29.4 6.9 1.5e-06 27.9 0.1 3.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ67391.1 - 8.2e-06 26.0 4.9 0.0015 18.9 0.1 4.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ67391.1 - 8.3e-06 25.3 4.5 0.15 12.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ67391.1 - 4.1e-05 23.8 0.5 4.1e-05 23.8 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CDJ67391.1 - 4.9e-05 23.3 3.1 0.00012 22.1 1.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CDJ67391.1 - 0.00016 22.2 0.2 0.00016 22.2 0.1 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ67391.1 - 0.00025 20.5 0.3 0.021 14.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ67391.1 - 0.00026 20.8 0.8 0.00069 19.4 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ67391.1 - 0.00026 21.2 3.0 0.015 15.7 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ67391.1 - 0.0097 16.0 0.8 0.036 14.2 0.5 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ67391.1 - 0.021 14.5 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDJ67391.1 - 0.022 14.6 0.1 5.6 6.9 0.0 2.7 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 CDJ67391.1 - 0.036 14.4 4.4 0.19 12.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RecO_C PF02565.10 CDJ67391.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Recombination protein O C terminal Abhydrolase_2 PF02230.11 CDJ67392.1 - 1.4e-49 168.4 0.0 2.7e-49 167.5 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CDJ67392.1 - 1.4e-08 34.6 0.0 2.6e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ67392.1 - 1.5e-07 31.5 0.4 5.1e-07 29.8 0.3 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 CDJ67392.1 - 0.0014 17.8 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase FSH1 PF03959.8 CDJ67392.1 - 0.0034 16.8 0.0 0.019 14.4 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 CDJ67392.1 - 0.0035 16.9 0.0 0.01 15.4 0.0 1.7 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDJ67392.1 - 0.021 14.0 0.1 2.2 7.4 0.0 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 CDJ67392.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase SET PF00856.23 CDJ67393.1 - 1.4e-05 25.5 0.0 0.026 14.8 0.0 2.6 2 0 0 2 2 2 2 SET domain Se-cys_synth_N PF12390.3 CDJ67393.1 - 0.74 9.9 4.6 0.21 11.6 0.2 2.5 2 0 0 2 2 2 0 Selenocysteine synthase N terminal SKIP_SNW PF02731.10 CDJ67394.1 - 3.4e-63 211.8 1.2 3.4e-63 211.8 0.8 3.0 3 0 0 3 3 3 1 SKIP/SNW domain DNA_pol_A PF00476.15 CDJ67396.1 - 2e-49 168.2 14.1 1.7e-32 112.5 1.6 5.8 4 2 0 5 5 5 4 DNA polymerase family A 5_3_exonuc PF01367.15 CDJ67396.1 - 8.6e-10 38.7 0.0 3.3e-09 36.8 0.0 2.1 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold RVT_1 PF00078.22 CDJ67397.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDJ67398.1 - 3.9e-11 42.4 0.0 7.3e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Myosin_head PF00063.16 CDJ67400.1 - 1.1e-13 50.1 0.1 1.5e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) SR-25 PF10500.4 CDJ67401.1 - 0.0048 16.3 6.9 0.0055 16.2 4.8 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4179 PF13786.1 CDJ67401.1 - 0.1 12.8 1.0 0.15 12.3 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) RskA PF10099.4 CDJ67401.1 - 8.6 6.0 14.1 59 3.3 9.8 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Collagen PF01391.13 CDJ67402.1 - 3.3e-06 26.5 26.5 3.3e-06 26.5 18.4 7.6 4 2 1 5 5 5 2 Collagen triple helix repeat (20 copies) DUF3123 PF11321.3 CDJ67402.1 - 7 6.9 8.8 12 6.1 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Nop53 PF07767.6 CDJ67403.1 - 6.1e-20 71.5 39.4 3.3e-13 49.3 12.8 2.5 1 1 1 2 2 2 2 Nop53 (60S ribosomal biogenesis) SR-25 PF10500.4 CDJ67403.1 - 0.0052 16.2 20.2 0.0052 16.2 14.0 3.9 2 2 1 3 3 3 1 Nuclear RNA-splicing-associated protein La PF05383.12 CDJ67404.1 - 1.4e-08 34.4 0.0 0.00071 19.3 0.0 2.4 2 0 0 2 2 2 2 La domain SR-25 PF10500.4 CDJ67404.1 - 0.0073 15.8 19.3 0.0073 15.8 13.4 7.8 6 2 1 7 7 7 1 Nuclear RNA-splicing-associated protein Peptidase_C12 PF01088.16 CDJ67405.1 - 7.6e-25 87.3 0.2 7.6e-25 87.3 0.2 4.7 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase, family 1 FxsA PF04186.8 CDJ67405.1 - 3.1 7.4 0.0 3.1 7.4 0.0 3.8 5 0 0 5 5 5 0 FxsA cytoplasmic membrane protein Hydrolase PF00702.21 CDJ67406.1 - 7.2e-18 65.7 9.6 7.2e-18 65.7 6.7 4.7 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CDJ67406.1 - 8.3e-16 57.7 9.6 2e-15 56.4 0.0 3.9 3 1 1 4 4 4 1 E1-E2 ATPase HAD PF12710.2 CDJ67406.1 - 5.9e-10 39.6 0.0 1.8e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CDJ67406.1 - 3.8e-08 33.3 0.2 2.2e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain ATG27 PF09451.5 CDJ67406.1 - 0.3 10.2 1.9 0.67 9.1 1.3 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 SeqA PF03925.8 CDJ67406.1 - 0.34 10.5 4.6 0.85 9.2 3.2 1.6 1 0 0 1 1 1 0 SeqA protein Hydrolase_3 PF08282.7 CDJ67406.1 - 0.45 10.0 6.3 0.85 9.1 0.4 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DDHD PF02862.12 CDJ67406.1 - 0.65 9.7 8.9 2.4 7.8 4.4 2.4 2 0 0 2 2 2 0 DDHD domain Bul1_C PF04426.7 CDJ67406.1 - 1.7 7.7 12.9 8.8 5.4 0.1 2.2 2 0 0 2 2 2 0 Bul1 C terminus Methyltransf_5 PF01795.14 CDJ67408.1 - 0.0034 16.7 0.0 0.02 14.2 0.0 1.9 2 0 0 2 2 2 1 MraW methylase family FimP PF09766.4 CDJ67408.1 - 0.038 13.0 3.3 0.045 12.8 2.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDJ67408.1 - 0.15 11.4 2.6 0.18 11.1 1.8 1.1 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.4 CDJ67408.1 - 0.24 9.6 9.1 0.27 9.4 6.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ67408.1 - 0.51 8.4 22.8 0.85 7.7 15.8 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDJ67409.1 - 0.001 18.5 1.4 0.001 18.5 0.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2042 PF09743.4 CDJ67410.1 - 9.1e-15 54.6 0.1 1e-14 54.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) ABC_tran PF00005.22 CDJ67414.1 - 1.1e-48 165.0 0.0 2e-26 92.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CDJ67414.1 - 3.2e-33 115.2 30.8 1.3e-29 103.2 1.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CDJ67414.1 - 2.5e-16 60.4 0.2 2.3e-06 27.7 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 CDJ67414.1 - 1.6e-06 27.5 1.5 0.047 13.2 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 CDJ67414.1 - 0.0004 19.6 0.2 0.018 14.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CDJ67414.1 - 0.0021 18.4 5.6 0.029 14.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.17 CDJ67414.1 - 0.015 14.7 0.5 0.099 12.0 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 CDJ67414.1 - 0.019 14.9 0.2 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 CDJ67414.1 - 0.025 14.5 0.8 1.3 9.0 0.4 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 CDJ67414.1 - 0.042 13.7 0.0 7.5 6.5 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CDJ67414.1 - 0.12 12.1 3.2 2.3 7.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 CDJ67414.1 - 0.27 10.7 0.3 28 4.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CDJ67414.1 - 0.53 9.6 2.0 1.9 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 CDJ67414.1 - 0.81 8.4 4.5 1 8.0 0.3 2.4 3 0 0 3 3 3 0 ArgK protein AAA_15 PF13175.1 CDJ67414.1 - 1.9 7.4 0.0 24 3.8 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_10 PF12846.2 CDJ67414.1 - 6.5 6.0 7.3 8.6 5.6 0.7 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_13 PF13166.1 CDJ67414.1 - 8.2 4.7 3.4 28 2.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain Chorion_2 PF03964.10 CDJ67416.1 - 0.0013 19.2 32.5 0.023 15.2 1.5 3.8 3 0 0 3 3 3 2 Chorion family 2 Pex14_N PF04695.8 CDJ67416.1 - 0.84 9.6 7.2 0.28 11.2 2.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 CDJ67417.1 - 0.0051 16.1 3.5 0.007 15.7 2.4 1.4 1 0 0 1 1 1 1 Spt20 family Suf PF05843.9 CDJ67417.1 - 0.0061 16.3 10.6 0.0079 15.9 7.3 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ67417.1 - 0.011 14.8 13.3 0.016 14.2 9.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF3451 PF11933.3 CDJ67417.1 - 0.044 13.5 6.9 0.074 12.8 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) CDC45 PF02724.9 CDJ67417.1 - 0.047 11.7 8.6 0.055 11.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.5 CDJ67417.1 - 0.076 11.2 34.7 0.1 10.7 24.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDJ67417.1 - 0.077 10.7 4.7 0.071 10.8 3.3 1.1 1 0 0 1 1 1 0 Ycf1 Draxin PF15550.1 CDJ67417.1 - 0.17 11.5 10.6 0.24 11.0 7.3 1.2 1 0 0 1 1 1 0 Draxin XAP5 PF04921.9 CDJ67417.1 - 0.31 10.5 5.0 0.46 10.0 3.5 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator Utp14 PF04615.8 CDJ67417.1 - 0.85 7.7 19.3 1 7.4 13.3 1.1 1 0 0 1 1 1 0 Utp14 protein SAPS PF04499.10 CDJ67417.1 - 0.87 8.1 9.0 0.93 8.0 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SUFU_C PF12470.3 CDJ67417.1 - 0.89 9.1 7.1 1.3 8.5 4.9 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain AAA_23 PF13476.1 CDJ67417.1 - 0.91 9.8 7.5 1.4 9.2 5.2 1.4 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 CDJ67417.1 - 0.99 8.1 12.6 1.3 7.8 8.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Plasmodium_Vir PF05795.6 CDJ67417.1 - 1 8.5 2.5 1.1 8.3 1.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Raftlin PF15250.1 CDJ67417.1 - 1.4 7.3 10.8 1.8 6.9 7.5 1.1 1 0 0 1 1 1 0 Raftlin SR-25 PF10500.4 CDJ67417.1 - 1.6 8.1 15.2 2.4 7.5 10.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Lin-8 PF03353.10 CDJ67417.1 - 1.9 7.6 12.6 2.3 7.4 8.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PPP4R2 PF09184.6 CDJ67417.1 - 2.5 7.5 12.6 3.5 7.1 8.8 1.2 1 0 0 1 1 1 0 PPP4R2 U1snRNP70_N PF12220.3 CDJ67417.1 - 2.5 8.4 14.5 53 4.2 9.6 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PAT1 PF09770.4 CDJ67417.1 - 3.5 5.7 31.6 3.9 5.6 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 vMSA PF00695.14 CDJ67417.1 - 3.6 6.6 6.2 4.4 6.4 4.3 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Serinc PF03348.10 CDJ67417.1 - 4.7 5.8 8.6 6.8 5.2 6.0 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Parvo_coat PF00740.13 CDJ67417.1 - 4.7 6.0 11.9 5.6 5.7 8.3 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Zip PF02535.17 CDJ67417.1 - 4.8 6.1 5.7 6.5 5.6 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM176 PF14851.1 CDJ67417.1 - 5.7 6.5 8.4 11 5.7 5.8 1.5 1 0 0 1 1 1 0 FAM176 family Glyco_transf_15 PF01793.11 CDJ67417.1 - 5.9 5.7 8.3 7.5 5.3 5.7 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF3381 PF11861.3 CDJ67417.1 - 6.5 6.2 13.2 12 5.3 9.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF940 PF06082.6 CDJ67417.1 - 7.1 5.0 12.7 8.1 4.8 8.8 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) FAM60A PF15396.1 CDJ67417.1 - 7.4 6.2 9.1 11 5.7 6.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Ndc1_Nup PF09531.5 CDJ67417.1 - 7.8 4.7 8.1 7.9 4.7 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1675 PF07897.6 CDJ67417.1 - 8.1 6.2 12.9 13 5.5 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FHIPEP PF00771.15 CDJ67417.1 - 9.4 4.4 13.4 12 4.0 9.2 1.3 1 1 0 1 1 1 0 FHIPEP family RNase_PH PF01138.16 CDJ67418.1 - 5.3e-11 42.9 0.0 8.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CDJ67418.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 VHS PF00790.14 CDJ67419.1 - 0.011 15.3 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 VHS domain KH_1 PF00013.24 CDJ67419.1 - 0.099 12.3 0.0 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 KH domain Melibiase PF02065.13 CDJ67419.1 - 1.7 7.2 7.1 0.24 10.0 0.1 2.1 1 1 0 2 2 2 0 Melibiase UFC1 PF08694.6 CDJ67421.1 - 9.7e-77 255.9 0.0 1.1e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 CDJ67421.1 - 0.0031 16.9 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDJ67421.1 - 0.0055 16.4 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Glyco_hydro_61 PF03443.9 CDJ67421.1 - 0.018 14.8 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 PAP_assoc PF03828.14 CDJ67422.1 - 0.00016 21.5 0.1 0.0014 18.5 0.1 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase Spore-coat_CotZ PF10612.4 CDJ67423.1 - 0.02 14.7 0.7 0.088 12.6 0.0 2.3 3 1 0 3 3 3 0 Spore coat protein Z DUF4604 PF15377.1 CDJ67423.1 - 0.034 14.3 5.1 0.053 13.7 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SRP-alpha_N PF04086.8 CDJ67423.1 - 0.1 11.9 0.7 0.13 11.5 0.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BAF1_ABF1 PF04684.8 CDJ67423.1 - 1.4 7.6 4.8 2.4 6.9 3.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cut8_N PF14482.1 CDJ67423.1 - 9.9 6.2 7.8 1.7 8.6 2.7 1.7 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Exo_endo_phos PF03372.18 CDJ67424.1 - 1.4e-10 41.5 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Collagen PF01391.13 CDJ67425.1 - 0.094 12.2 19.4 0.29 10.7 13.5 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) CAF-1_p150 PF11600.3 CDJ67426.1 - 0.0062 15.9 32.7 0.0089 15.4 22.7 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF605 PF04652.11 CDJ67426.1 - 0.083 12.2 38.5 0.1 11.9 26.7 1.2 1 0 0 1 1 1 0 Vta1 like CobT PF06213.7 CDJ67426.1 - 0.45 9.5 20.6 0.64 9.0 14.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PAT1 PF09770.4 CDJ67426.1 - 1.2 7.3 64.9 1.3 7.1 45.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDJ67426.1 - 2.9 7.7 30.4 3.8 7.3 21.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.1 CDJ67426.1 - 3.2 5.8 11.0 3.5 5.6 7.6 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Paf1 PF03985.8 CDJ67426.1 - 3.3 6.3 31.5 4.8 5.8 21.9 1.2 1 0 0 1 1 1 0 Paf1 Asp-B-Hydro_N PF05279.6 CDJ67426.1 - 5.4 6.7 22.7 6.7 6.4 15.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spore_coat_CotO PF14153.1 CDJ67426.1 - 8.6 5.7 39.9 13 5.1 27.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF2312 PF10073.4 CDJ67427.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF3206 PF11472.3 CDJ67427.1 - 0.06 13.1 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) DUF3273 PF11677.3 CDJ67428.1 - 1.1e-26 93.7 4.1 1.3e-26 93.4 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2568 PF10823.3 CDJ67428.1 - 0.0012 19.0 0.4 0.0026 17.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2568) DUF3273 PF11677.3 CDJ67429.1 - 1.6e-35 122.6 8.0 1.8e-35 122.4 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2568 PF10823.3 CDJ67429.1 - 0.00049 20.2 0.5 0.0012 19.0 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2568) DUF4139 PF13598.1 CDJ67430.1 - 0.41 9.9 6.6 0.46 9.7 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Hc1 PF07432.8 CDJ67430.1 - 2.3 8.4 18.6 2.7 8.1 12.9 1.1 1 0 0 1 1 1 0 Histone H1-like protein Hc1 MSP1_C PF07462.6 CDJ67430.1 - 2.8 6.2 11.7 3 6.1 8.1 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Med3 PF11593.3 CDJ67430.1 - 4.5 6.4 10.7 5.1 6.2 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fmp27_WPPW PF10359.4 CDJ67431.1 - 0.037 12.4 2.3 0.048 12.0 1.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF755 PF05501.6 CDJ67431.1 - 0.05 13.6 23.5 0.077 13.0 16.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) APC_CDC26 PF10471.4 CDJ67431.1 - 0.11 13.2 9.7 0.18 12.5 6.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Apt1 PF10351.4 CDJ67431.1 - 0.15 10.9 9.1 0.18 10.6 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pex14_N PF04695.8 CDJ67431.1 - 0.5 10.4 11.7 5.3 7.0 6.9 2.7 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1517 PF07466.6 CDJ67431.1 - 1.5 7.7 7.6 0.37 9.7 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Macoilin PF09726.4 CDJ67431.1 - 3 6.0 11.0 4.1 5.5 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3138 PF11336.3 CDJ67431.1 - 3.4 5.7 10.5 1.1 7.3 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF2217 PF10265.4 CDJ67431.1 - 4.6 5.9 10.5 5.8 5.5 7.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PsbQ PF05757.6 CDJ67431.1 - 7 6.0 7.8 1.3 8.3 0.1 2.1 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Sporozoite_P67 PF05642.6 CDJ67431.1 - 8.1 4.1 10.1 0.46 8.2 3.5 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RVT_1 PF00078.22 CDJ67432.1 - 1.5e-17 63.6 0.0 2.8e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDJ67432.1 - 0.00021 21.4 0.0 0.00058 19.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_3 PF13456.1 CDJ67432.1 - 0.039 13.7 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.22 CDJ67434.1 - 4.9e-12 45.6 0.0 8.7e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CDJ67434.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like UvrD_C PF13361.1 CDJ67435.1 - 0.0082 15.6 0.9 0.0097 15.4 0.6 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Hydrolase_3 PF08282.7 CDJ67435.1 - 0.016 14.8 2.1 0.019 14.5 1.4 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Protocadherin PF08374.6 CDJ67435.1 - 0.024 14.2 1.8 0.026 14.1 1.2 1.2 1 0 0 1 1 1 0 Protocadherin DUF4312 PF14189.1 CDJ67435.1 - 0.078 12.8 0.2 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) Med6 PF04934.9 CDJ67435.1 - 1.3 8.5 5.4 2.2 7.8 3.8 1.4 1 1 0 1 1 1 0 MED6 mediator sub complex component FimP PF09766.4 CDJ67436.1 - 0.093 11.7 24.5 0.09 11.8 17.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein SprA-related PF12118.3 CDJ67436.1 - 0.17 11.1 34.1 0.15 11.3 23.6 1.1 1 0 0 1 1 1 0 SprA-related family Serinc PF03348.10 CDJ67436.1 - 0.26 9.9 12.3 0.25 9.9 8.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FHIPEP PF00771.15 CDJ67436.1 - 0.29 9.4 6.9 0.32 9.2 4.8 1.1 1 0 0 1 1 1 0 FHIPEP family RR_TM4-6 PF06459.7 CDJ67436.1 - 0.37 10.6 12.5 0.35 10.7 8.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CDJ67436.1 - 0.39 9.4 11.7 0.36 9.6 8.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DNA_pol3_a_NII PF11490.3 CDJ67436.1 - 0.48 10.0 22.6 0.54 9.8 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF808 PF05661.7 CDJ67436.1 - 0.49 9.1 3.8 0.57 8.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Gti1_Pac2 PF09729.4 CDJ67436.1 - 0.5 10.2 9.4 0.48 10.2 6.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CRF1 PF10380.4 CDJ67436.1 - 0.6 10.4 9.1 0.67 10.3 6.3 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Pex14_N PF04695.8 CDJ67436.1 - 0.8 9.7 25.0 0.82 9.7 17.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_23 PF13476.1 CDJ67436.1 - 0.87 9.8 17.7 0.82 9.9 12.3 1.1 1 0 0 1 1 1 0 AAA domain DDHD PF02862.12 CDJ67436.1 - 0.89 9.3 12.9 0.86 9.3 8.9 1.0 1 0 0 1 1 1 0 DDHD domain DUF3306 PF11748.3 CDJ67436.1 - 0.91 10.1 13.2 1.1 9.9 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) CPSF100_C PF13299.1 CDJ67436.1 - 1 9.4 11.0 0.97 9.6 7.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Cellulose_synt PF03552.9 CDJ67436.1 - 1.1 7.5 8.1 1 7.5 5.6 1.0 1 0 0 1 1 1 0 Cellulose synthase AIF_C PF14721.1 CDJ67436.1 - 1.3 9.2 12.7 1.4 9.1 8.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4011 PF13195.1 CDJ67436.1 - 1.4 8.8 9.2 1.4 8.9 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Band_3_cyto PF07565.8 CDJ67436.1 - 2 7.8 15.4 1.8 7.9 10.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Lant_dehyd_N PF04737.8 CDJ67436.1 - 2.2 8.3 10.9 28 4.7 7.5 2.1 1 1 0 1 1 1 0 Lantibiotic dehydratase, N terminus OmpH PF03938.9 CDJ67436.1 - 2.3 8.1 33.3 2.2 8.2 23.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AUX_IAA PF02309.11 CDJ67436.1 - 2.5 7.7 13.4 2.3 7.8 9.3 1.1 1 0 0 1 1 1 0 AUX/IAA family Baculo_PP31 PF05311.6 CDJ67436.1 - 2.5 7.2 15.8 2.4 7.3 11.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Hid1 PF12722.2 CDJ67436.1 - 2.8 5.5 15.4 2.5 5.6 10.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 CDJ67436.1 - 3.3 7.3 23.6 3.7 7.1 16.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dala_Dala_lig_N PF01820.16 CDJ67436.1 - 3.6 7.9 8.3 4.1 7.7 5.8 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus PH_4 PF15404.1 CDJ67436.1 - 3.7 7.0 14.5 4.3 6.8 10.1 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain NARP1 PF12569.3 CDJ67436.1 - 4.9 5.7 17.3 5 5.7 12.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4199 PF13858.1 CDJ67436.1 - 5.5 6.8 10.3 5.7 6.8 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Pal1 PF08316.6 CDJ67436.1 - 5.8 7.3 7.7 5.6 7.4 5.3 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein TraH_2 PF06871.6 CDJ67436.1 - 6.5 6.1 7.8 6.8 6.0 5.4 1.1 1 0 0 1 1 1 0 TraH_2 Dynamin_N PF00350.18 CDJ67436.1 - 6.8 6.4 9.8 6.8 6.4 6.8 1.1 1 0 0 1 1 1 0 Dynamin family DUF4557 PF15101.1 CDJ67436.1 - 7.2 6.3 29.4 7.6 6.3 20.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Peptidase_S15 PF02129.13 CDJ67436.1 - 7.4 5.9 11.6 6.7 6.0 8.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Kei1 PF08552.6 CDJ67436.1 - 7.5 6.1 11.6 8 6.0 8.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TFIIA PF03153.8 CDJ67436.1 - 8 6.2 30.0 7.5 6.3 20.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.7 CDJ67436.1 - 8.3 4.8 21.7 7.6 5.0 15.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) tRNA-synt_1c PF00749.16 CDJ67436.1 - 8.8 4.8 12.3 10 4.6 8.5 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Neur_chan_memb PF02932.11 CDJ67436.1 - 9 6.1 10.3 9 6.1 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peroxin-13_N PF04088.8 CDJ67436.1 - 9.7 6.1 9.5 11 5.9 6.6 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region EMP24_GP25L PF01105.19 CDJ67437.1 - 1.7e-08 34.3 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosomal_60s PF00428.14 CDJ67437.1 - 0.0018 18.6 16.3 0.0039 17.5 7.8 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_III PF05192.13 CDJ67437.1 - 0.12 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 MutS domain III Ribosomal_60s PF00428.14 CDJ67438.1 - 0.01 16.2 6.2 0.018 15.4 4.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Remorin_C PF03763.8 CDJ67438.1 - 0.023 14.1 5.0 0.042 13.3 3.4 1.4 1 1 0 1 1 1 0 Remorin, C-terminal region CorA PF01544.13 CDJ67438.1 - 0.031 13.3 5.4 0.046 12.7 3.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GED PF02212.13 CDJ67438.1 - 0.064 13.1 0.8 0.15 11.9 0.5 1.7 1 1 0 1 1 1 0 Dynamin GTPase effector domain ApoC-I PF04691.7 CDJ67438.1 - 0.11 12.2 1.9 0.25 11.0 0.2 2.2 1 1 2 3 3 3 0 Apolipoprotein C-I (ApoC-1) DUF572 PF04502.8 CDJ67438.1 - 0.13 11.4 2.3 0.16 11.1 1.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peripla_BP_2 PF01497.13 CDJ67438.1 - 0.15 11.1 2.6 0.29 10.2 1.8 1.4 1 1 0 1 1 1 0 Periplasmic binding protein Syntaxin_2 PF14523.1 CDJ67438.1 - 0.25 11.3 9.7 0.39 10.7 6.8 1.3 1 0 0 1 1 1 0 Syntaxin-like protein Trypan_glycop PF00913.14 CDJ67438.1 - 0.43 9.4 8.0 0.29 10.0 4.6 1.4 1 1 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF3646 PF12362.3 CDJ67438.1 - 0.81 9.6 6.2 0.095 12.6 1.0 1.8 1 1 1 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal HisKA_3 PF07730.8 CDJ67438.1 - 3.7 7.9 6.9 1.5 9.2 0.0 3.0 3 1 0 3 3 3 0 Histidine kinase FliT PF05400.8 CDJ67438.1 - 4.8 7.6 9.6 1 9.8 1.9 2.7 2 1 1 3 3 3 0 Flagellar protein FliT Peptidase_S49_N PF08496.5 CDJ67441.1 - 0.023 14.4 0.4 0.023 14.4 0.3 6.2 4 2 2 6 6 6 0 Peptidase family S49 N-terminal SAPS PF04499.10 CDJ67441.1 - 3.2 6.3 0.0 3.2 6.3 0.0 5.8 2 1 0 3 3 3 0 SIT4 phosphatase-associated protein Thioredoxin PF00085.15 CDJ67442.1 - 1.3e-57 191.9 0.3 1.5e-30 104.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CDJ67442.1 - 1e-24 87.3 0.0 2e-13 50.5 0.0 3.8 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CDJ67442.1 - 5.2e-12 45.9 2.2 8e-05 22.8 0.1 4.0 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CDJ67442.1 - 4.6e-10 39.3 5.1 0.00022 21.2 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CDJ67442.1 - 9e-10 38.5 0.1 0.0028 17.7 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CDJ67442.1 - 2.4e-07 30.4 0.2 0.00023 20.8 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CDJ67442.1 - 5e-06 26.1 0.6 0.0073 15.8 0.0 2.6 2 0 0 2 2 2 2 Redoxin Calsequestrin PF01216.12 CDJ67442.1 - 6.9e-06 25.0 0.0 1.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_9 PF14595.1 CDJ67442.1 - 0.0002 20.8 0.0 0.079 12.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.1 CDJ67442.1 - 0.00082 18.9 0.0 0.073 12.5 0.0 2.5 2 0 0 2 2 2 1 F plasmid transfer operon protein NMD3 PF04981.8 CDJ67442.1 - 0.00099 18.2 0.0 0.33 10.0 0.0 2.2 2 0 0 2 2 2 2 NMD3 family ERp29_N PF07912.8 CDJ67442.1 - 0.0026 17.6 0.0 2.8 7.8 0.0 3.2 3 1 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 CDJ67442.1 - 0.49 10.3 4.1 13 5.7 0.1 3.6 3 2 1 4 4 4 0 Thioredoxin Glutaredoxin PF00462.19 CDJ67442.1 - 1.6 8.7 5.8 17 5.4 0.3 3.4 3 2 0 3 3 3 0 Glutaredoxin DUF1510 PF07423.6 CDJ67443.1 - 0.097 12.0 50.2 0.093 12.0 7.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Herpes_UL87 PF03043.9 CDJ67443.1 - 4.3 5.6 30.2 5.5 5.2 20.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Med15 PF09606.5 CDJ67443.1 - 4.7 5.2 99.1 6.7 4.7 68.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3437 PF11919.3 CDJ67444.1 - 1.5e-22 79.1 0.0 5.6e-22 77.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Ribosomal_60s PF00428.14 CDJ67444.1 - 0.0047 17.2 1.0 0.0047 17.2 0.7 10.5 9 1 1 10 10 10 3 60s Acidic ribosomal protein Ycf1 PF05758.7 CDJ67444.1 - 0.079 10.6 3.5 0.15 9.7 2.4 1.4 1 0 0 1 1 1 0 Ycf1 DEAD PF00270.24 CDJ67445.1 - 2.6e-18 66.1 10.6 1.4e-13 50.6 2.0 4.3 3 1 1 4 4 4 3 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ67445.1 - 4.5e-08 32.8 0.0 4.5e-08 32.8 0.0 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain Adaptin_binding PF10199.4 CDJ67445.1 - 0.00034 20.9 27.2 0.018 15.2 3.3 6.7 6 1 1 7 7 7 2 Alpha and gamma adaptin binding protein p34 Ycf1 PF05758.7 CDJ67445.1 - 0.00079 17.2 3.9 0.00079 17.2 2.7 2.8 3 0 0 3 3 3 1 Ycf1 Adap_comp_sub PF00928.16 CDJ67447.1 - 6.3e-06 25.4 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family EI24 PF07264.6 CDJ67448.1 - 8e-11 41.7 25.8 0.00019 20.9 16.6 3.8 2 1 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) SprA-related PF12118.3 CDJ67448.1 - 0.00018 20.9 22.3 0.00018 20.9 15.4 6.1 5 1 0 5 5 5 1 SprA-related family RAP1 PF07218.6 CDJ67448.1 - 0.29 9.1 6.3 0.018 13.1 0.4 1.7 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) GTP_EFTU_D2 PF03144.20 CDJ67449.1 - 0.00013 21.9 0.2 0.00025 21.1 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 CDJ67449.1 - 0.00086 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Med3 PF11593.3 CDJ67451.1 - 0.24 10.5 5.3 0.31 10.2 3.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L2_C PF03947.13 CDJ67453.1 - 6.6e-41 139.1 1.5 1e-40 138.5 1.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CDJ67453.1 - 3.6e-18 65.3 0.1 7.4e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TPR_11 PF13414.1 CDJ67454.1 - 4e-12 45.6 1.7 2.6e-06 26.9 0.0 3.9 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 CDJ67454.1 - 0.00047 19.6 0.5 0.028 14.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ67454.1 - 0.0036 17.9 0.9 0.0036 17.9 0.7 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF755 PF05501.6 CDJ67454.1 - 0.0039 17.2 3.8 0.0039 17.2 2.7 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF755) Fis1_TPR_C PF14853.1 CDJ67454.1 - 0.1 12.4 2.1 0.16 11.9 0.3 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DNA_pol_viral_N PF00242.12 CDJ67454.1 - 0.14 11.1 10.0 0.26 10.2 6.9 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2217 PF10265.4 CDJ67454.1 - 0.28 9.8 4.8 0.42 9.3 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PIG-P PF08510.7 CDJ67455.1 - 2.2e-29 101.6 0.1 1e-28 99.4 0.0 1.8 1 1 0 1 1 1 1 PIG-P PgaD PF13994.1 CDJ67455.1 - 0.011 15.2 0.1 0.011 15.2 0.1 1.5 2 0 0 2 2 2 0 PgaD-like protein RDD PF06271.7 CDJ67455.1 - 0.12 12.2 0.6 12 5.7 0.1 2.1 2 0 0 2 2 2 0 RDD family CMV_US PF08001.6 CDJ67455.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 CMV US DUF4131 PF13567.1 CDJ67455.1 - 0.25 10.7 3.6 0.26 10.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) FixQ PF05545.6 CDJ67455.1 - 2.7 7.6 11.3 1.2 8.8 0.8 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ RCC1 PF00415.13 CDJ67456.1 - 7.4e-14 51.6 0.5 0.00041 20.5 0.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ67456.1 - 0.025 14.1 8.8 4.2 7.1 0.0 4.6 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CDJ67457.1 - 4.5e-17 61.9 0.0 8.6e-06 25.8 0.0 4.2 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ67457.1 - 1.4e-13 50.0 16.1 1.4e-08 34.0 1.3 3.3 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Aldo_ket_red PF00248.16 CDJ67459.1 - 2.7e-42 144.5 0.0 3.2e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SUI1 PF01253.17 CDJ67460.1 - 3.5e-12 45.9 0.0 6.2e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 zf-His_Me_endon PF05551.6 CDJ67461.1 - 0.035 14.0 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease Hydrolase PF00702.21 CDJ67463.1 - 7.9e-19 68.9 0.0 1.4e-16 61.5 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CDJ67463.1 - 1.1e-14 54.0 7.3 2.5e-07 29.9 1.4 3.3 4 0 0 4 4 4 2 E1-E2 ATPase HAD PF12710.2 CDJ67463.1 - 4.3e-13 49.8 0.0 1.2e-12 48.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDJ67463.1 - 2.4e-07 30.5 0.0 7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD_2 PF13419.1 CDJ67463.1 - 0.00064 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDJ67463.1 - 0.0027 17.3 0.0 0.0078 15.8 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2076 PF09849.4 CDJ67463.1 - 1.3 9.0 4.3 1.8 8.5 3.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Zn-ribbon_8 PF09723.5 CDJ67464.1 - 0.21 11.5 1.1 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain tRNA-synt_2b PF00587.20 CDJ67465.1 - 3.8e-43 147.0 0.1 6.9e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CDJ67465.1 - 2.4e-21 75.4 0.1 5.5e-21 74.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 CDJ67465.1 - 3.3e-10 39.6 0.0 8.1e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 CDJ67465.1 - 1.6e-07 31.0 0.0 1.5e-06 27.9 0.0 2.6 2 1 0 2 2 2 1 TGS domain EnY2 PF10163.4 CDJ67466.1 - 1.9e-06 27.7 0.1 3.1e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 Cofilin_ADF PF00241.15 CDJ67467.1 - 2.1e-29 102.0 0.0 2.6e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein WBP-1 PF11669.3 CDJ67468.1 - 0.2 11.7 1.5 0.17 12.0 0.2 1.5 1 1 1 2 2 2 0 WW domain-binding protein 1 DUF1461 PF07314.6 CDJ67468.1 - 0.83 9.3 3.2 0.99 9.1 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Rtf2 PF04641.7 CDJ67469.1 - 1.8e-44 151.8 0.1 2.8e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CDJ67469.1 - 0.00063 19.4 0.0 0.0018 17.9 0.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CDJ67469.1 - 0.0047 16.7 0.1 0.0089 15.8 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain PPP1R35_C PF15503.1 CDJ67469.1 - 0.054 13.0 0.4 0.1 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Aconitase PF00330.15 CDJ67470.1 - 3.2e-147 490.7 0.0 3.8e-147 490.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CDJ67470.1 - 1.6e-40 138.2 0.0 2.6e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-RING_2 PF13639.1 CDJ67471.1 - 2.1e-07 30.6 0.2 4e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain WBP-1 PF11669.3 CDJ67471.1 - 0.0054 16.7 1.2 0.0054 16.7 0.8 1.6 2 0 0 2 2 2 1 WW domain-binding protein 1 zf-C3HC4_2 PF13923.1 CDJ67471.1 - 0.0064 16.4 1.4 0.0081 16.1 0.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ67471.1 - 0.011 15.5 0.3 0.023 14.4 0.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.1 CDJ67471.1 - 0.032 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.2 CDJ67471.1 - 0.035 14.2 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDJ67471.1 - 0.1 12.2 0.4 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4234 PF14018.1 CDJ67471.1 - 0.32 10.7 8.5 4.4 7.1 6.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) STOP PF05217.7 CDJ67472.1 - 9e-37 126.8 1.6 1.2e-27 97.1 0.2 2.1 1 1 1 2 2 2 2 STOP protein BMF PF15185.1 CDJ67472.1 - 0.0081 15.4 2.7 2.8 7.1 0.1 3.0 1 1 3 4 4 4 2 Bcl-2-modifying factor, apoptosis PDEase_I PF00233.14 CDJ67473.1 - 5.7e-33 114.6 0.1 7.2e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase EIAV_GP90 PF00971.13 CDJ67473.1 - 0.057 11.8 0.0 0.081 11.3 0.0 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 DUF2809 PF10990.3 CDJ67474.1 - 0.13 12.7 1.6 0.29 11.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) Peptidase_U4 PF03419.8 CDJ67474.1 - 0.26 10.3 2.1 0.39 9.7 1.5 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA ADK PF00406.17 CDJ67476.1 - 4.6e-29 101.2 0.0 5.7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 CDJ67476.1 - 9.6e-10 39.3 0.0 3.7e-09 37.4 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CDJ67476.1 - 8.8e-05 22.4 0.0 0.00021 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDJ67476.1 - 0.00072 19.8 0.0 0.0018 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.9 CDJ67476.1 - 0.00085 18.9 2.5 0.0023 17.5 1.8 1.8 1 1 0 1 1 1 1 Adenylate kinase, active site lid AAA PF00004.24 CDJ67476.1 - 0.0091 16.1 0.3 0.068 13.3 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDJ67476.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SKI PF01202.17 CDJ67476.1 - 0.024 14.5 0.0 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate kinase SET PF00856.23 CDJ67477.1 - 9.5e-05 22.7 3.7 0.0032 17.7 0.2 3.1 4 0 0 4 4 4 2 SET domain ubiquitin PF00240.18 CDJ67481.1 - 0.029 13.7 0.0 0.071 12.5 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin family MelC1 PF06236.6 CDJ67481.1 - 0.041 13.8 0.2 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 DUF4131 PF13567.1 CDJ67481.1 - 0.094 12.1 2.0 0.19 11.1 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Coatomer_WDAD PF04053.9 CDJ67482.1 - 1.3e-05 24.2 1.5 0.0047 15.7 0.4 3.2 3 0 0 3 3 3 2 Coatomer WD associated region Voldacs PF03517.8 CDJ67484.1 - 2.4e-29 101.9 0.0 3.6e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF1448 PF07289.6 CDJ67484.1 - 0.0098 14.8 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Lipase_3 PF01764.20 CDJ67485.1 - 5.1e-13 48.8 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Retrotrans_gag PF03732.12 CDJ67486.1 - 0.0021 18.0 0.0 0.0063 16.5 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Chromo PF00385.19 CDJ67487.1 - 2.5e-12 46.2 0.0 4.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Med15 PF09606.5 CDJ67488.1 - 0.36 8.9 58.2 0.41 8.8 40.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3474 PF11960.3 CDJ67488.1 - 0.67 9.9 5.1 1.1 9.3 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) PAT1 PF09770.4 CDJ67488.1 - 7 4.7 42.9 7.8 4.6 29.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3810 PF12725.2 CDJ67489.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) EphA2_TM PF14575.1 CDJ67489.1 - 0.74 10.2 0.1 0.74 10.2 0.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Anoctamin PF04547.7 CDJ67489.1 - 0.78 8.3 5.2 0.44 9.1 2.3 1.4 2 0 0 2 2 2 0 Calcium-activated chloride channel HlyD_2 PF12700.2 CDJ67489.1 - 8.4 5.4 9.1 1.4 7.9 2.9 2.0 2 0 0 2 2 2 0 HlyD family secretion protein GcpE PF04551.9 CDJ67490.1 - 9e-135 449.0 0.0 2.5e-133 444.3 0.0 2.1 1 1 0 1 1 1 1 GcpE protein Spore_coat_CotO PF14153.1 CDJ67490.1 - 0.00033 20.1 9.7 0.00033 20.1 6.7 5.1 4 1 1 5 5 5 1 Spore coat protein CotO LRR_4 PF12799.2 CDJ67491.1 - 4.8e-10 38.8 4.8 4.7e-08 32.4 0.7 2.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) DUF1645 PF07816.6 CDJ67491.1 - 0.0044 17.5 5.2 0.0062 17.0 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) LRR_8 PF13855.1 CDJ67491.1 - 0.011 15.5 7.9 0.082 12.6 4.4 2.2 1 1 1 2 2 2 0 Leucine rich repeat LRR_6 PF13516.1 CDJ67491.1 - 1.8 8.8 7.9 21 5.5 0.0 3.8 2 1 1 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 CDJ67491.1 - 4.1 7.8 9.3 45 4.6 0.0 4.1 2 1 0 2 2 2 0 Leucine Rich Repeat CAF-1_p150 PF11600.3 CDJ67491.1 - 7.5 5.8 7.3 9.3 5.5 5.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDK2AP PF09806.4 CDJ67492.1 - 0.42 10.8 4.0 0.62 10.2 2.8 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein IncA PF04156.9 CDJ67493.1 - 0.0048 16.5 11.1 0.007 15.9 7.7 1.2 1 0 0 1 1 1 1 IncA protein BcsB PF03170.8 CDJ67493.1 - 0.16 9.9 10.5 0.21 9.5 7.3 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Activator_LAG-3 PF11498.3 CDJ67493.1 - 1.2 7.8 37.5 1.6 7.3 26.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FliP PF00813.15 CDJ67493.1 - 2.5 7.7 5.0 3 7.5 3.4 1.1 1 0 0 1 1 1 0 FliP family TFIIA PF03153.8 CDJ67493.1 - 2.7 7.7 21.3 4.2 7.1 14.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HA2 PF04408.18 CDJ67494.1 - 8.3e-21 73.9 0.2 8.3e-21 73.9 0.1 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CDJ67494.1 - 4.4e-08 32.8 0.0 4.4e-08 32.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Pex14_N PF04695.8 CDJ67494.1 - 4 7.4 22.0 7.8 6.5 7.9 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TctB PF07331.6 CDJ67495.1 - 0.001 18.7 5.0 0.026 14.2 0.6 2.8 1 1 1 2 2 2 2 Tripartite tricarboxylate transporter TctB family Herpes_US9 PF06072.6 CDJ67495.1 - 0.0036 17.0 7.7 0.024 14.4 0.6 4.4 4 1 0 4 4 4 2 Alphaherpesvirus tegument protein US9 DUF4079 PF13301.1 CDJ67495.1 - 0.67 9.9 13.0 3 7.8 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF3357 PF11837.3 CDJ67495.1 - 1.5 8.7 12.7 9 6.1 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) 7tm_1 PF00001.16 CDJ67495.1 - 3.1 6.8 6.0 0.83 8.7 0.4 2.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) VHS PF00790.14 CDJ67496.1 - 0.00023 20.8 0.2 0.24 11.0 0.0 2.2 2 0 0 2 2 2 2 VHS domain Pap_E4 PF02711.9 CDJ67497.1 - 0.027 15.2 3.7 0.027 15.2 2.6 4.2 2 1 1 3 3 3 0 E4 protein Vps53_N PF04100.7 CDJ67500.1 - 1.4e-42 145.8 3.2 1.9e-26 92.7 0.9 2.7 3 0 0 3 3 3 2 Vps53-like, N-terminal Hid1 PF12722.2 CDJ67501.1 - 2.9 5.4 14.2 4.2 4.9 9.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Archease PF01951.11 CDJ67502.1 - 2.3e-22 79.4 4.4 8.4e-11 41.9 0.7 2.3 1 1 1 2 2 2 2 Archease protein family (MTH1598/TM1083) AAA_23 PF13476.1 CDJ67502.1 - 0.022 15.1 3.5 0.033 14.5 2.4 1.3 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.6 CDJ67502.1 - 0.036 12.1 14.7 0.049 11.7 10.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HAUS4 PF14735.1 CDJ67502.1 - 0.055 12.7 14.9 0.09 12.0 10.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 E7 PF00527.13 CDJ67502.1 - 0.063 13.4 14.2 1.1 9.3 3.3 2.5 2 0 0 2 2 2 0 E7 protein, Early protein DUF1517 PF07466.6 CDJ67502.1 - 0.093 11.7 14.4 1.8 7.5 10.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Nse4_C PF08743.5 CDJ67502.1 - 0.32 11.0 4.8 13 5.8 1.0 2.7 2 0 0 2 2 2 0 Nse4 C-terminal DUF2489 PF10675.4 CDJ67502.1 - 0.39 10.4 20.5 0.53 9.9 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) Eapp_C PF10238.4 CDJ67502.1 - 1.3 8.9 10.1 0.53 10.1 0.5 2.9 3 0 0 3 3 3 0 E2F-associated phosphoprotein DUF508 PF04370.7 CDJ67502.1 - 6.3 6.4 11.5 9.8 5.7 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Vps39_1 PF10366.4 CDJ67502.1 - 7.1 6.7 8.4 3.8 7.5 2.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DUF788 PF05620.6 CDJ67502.1 - 8 6.2 9.6 3 7.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Spore_coat_CotO PF14153.1 CDJ67503.1 - 0.0032 16.9 9.0 0.0032 16.9 6.3 2.3 2 0 0 2 2 2 1 Spore coat protein CotO Ycf1 PF05758.7 CDJ67503.1 - 0.0041 14.9 8.0 0.054 11.2 2.4 2.0 2 0 0 2 2 2 2 Ycf1 Raftlin PF15250.1 CDJ67503.1 - 0.093 11.2 15.2 0.082 11.4 2.9 2.1 2 0 0 2 2 2 0 Raftlin PBP_sp32 PF07222.7 CDJ67503.1 - 0.36 9.9 24.8 0.2 10.8 1.8 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Neur_chan_memb PF02932.11 CDJ67503.1 - 0.36 10.6 16.0 1.6 8.5 1.6 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4557 PF15101.1 CDJ67503.1 - 0.71 9.6 40.9 0.29 10.9 14.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) SelP_N PF04592.9 CDJ67503.1 - 1.5 8.1 18.7 2.7 7.2 2.4 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region FAM60A PF15396.1 CDJ67503.1 - 1.5 8.4 18.2 0.32 10.7 2.9 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Plasmodium_Vir PF05795.6 CDJ67503.1 - 1.6 7.8 9.8 4.2 6.4 1.5 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Gti1_Pac2 PF09729.4 CDJ67503.1 - 1.7 8.4 14.8 0.13 12.1 1.6 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Serinc PF03348.10 CDJ67503.1 - 2.5 6.6 18.0 4.2 5.9 6.5 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) PA26 PF04636.8 CDJ67503.1 - 2.9 6.5 12.5 1.6 7.3 1.1 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Dala_Dala_lig_N PF01820.16 CDJ67503.1 - 3.8 7.8 11.8 0.97 9.7 2.7 2.6 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Band_3_cyto PF07565.8 CDJ67503.1 - 4.5 6.7 23.4 0.35 10.3 6.2 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Activator_LAG-3 PF11498.3 CDJ67503.1 - 5 5.7 64.1 0.56 8.9 7.6 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DDHD PF02862.12 CDJ67503.1 - 7.1 6.3 23.4 0.96 9.2 5.5 2.3 2 0 0 2 2 2 0 DDHD domain FLO_LFY PF01698.11 CDJ67503.1 - 8 5.1 20.6 0.48 9.2 5.5 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein Paf1 PF03985.8 CDJ67503.1 - 9.1 4.8 29.8 0.38 9.4 9.8 2.1 2 0 0 2 2 2 0 Paf1 DUF1510 PF07423.6 CDJ67503.1 - 9.8 5.4 28.9 7.2 5.9 8.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3450 PF11932.3 CDJ67505.1 - 2.7 7.1 7.2 3.8 6.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4139 PF13598.1 CDJ67505.1 - 3.3 6.9 7.4 4.1 6.6 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Tau95 PF09734.4 CDJ67506.1 - 0.0019 17.5 0.0 0.012 14.9 0.0 2.2 1 1 1 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF808 PF05661.7 CDJ67506.1 - 0.0043 15.9 4.3 0.012 14.4 0.4 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF808) Lipase_3 PF01764.20 CDJ67506.1 - 0.029 13.9 0.0 0.084 12.4 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) Zip PF02535.17 CDJ67506.1 - 0.64 8.9 11.1 0.14 11.1 4.7 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Ycf1 PF05758.7 CDJ67506.1 - 8.9 3.8 15.7 1.2 6.7 6.6 2.1 2 0 0 2 2 2 0 Ycf1 PAD_M PF08527.5 CDJ67507.1 - 0.33 10.3 2.0 0.31 10.4 1.4 1.0 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain PGA2 PF07543.7 CDJ67507.1 - 0.43 10.3 5.6 0.44 10.3 3.9 1.0 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF1853 PF08907.6 CDJ67507.1 - 1 8.5 8.5 1.1 8.4 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) APC_CDC26 PF10471.4 CDJ67507.1 - 1.6 9.5 23.0 1.7 9.4 15.9 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DivIC PF04977.10 CDJ67507.1 - 6 6.4 16.1 6.3 6.3 11.2 1.1 1 0 0 1 1 1 0 Septum formation initiator dsDNA_bind PF01984.15 CDJ67507.1 - 7.3 6.6 24.1 8 6.5 16.7 1.0 1 0 0 1 1 1 0 Double-stranded DNA-binding domain AIF_C PF14721.1 CDJ67507.1 - 7.3 6.8 6.5 6.6 6.9 4.5 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FlaG PF03646.10 CDJ67507.1 - 8.1 6.6 15.0 8.3 6.6 10.4 1.0 1 0 0 1 1 1 0 FlaG protein OmpH PF03938.9 CDJ67508.1 - 0.012 15.5 18.3 0.013 15.4 12.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) eIF_4EBP PF05456.6 CDJ67508.1 - 0.013 15.2 3.6 0.015 14.9 2.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Helicase_IV_N PF12462.3 CDJ67508.1 - 0.019 14.6 10.9 0.02 14.5 7.6 1.1 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Mob_Pre PF01076.14 CDJ67508.1 - 0.02 14.5 3.2 0.023 14.3 2.2 1.1 1 0 0 1 1 1 0 Plasmid recombination enzyme STN PF07660.9 CDJ67508.1 - 0.063 12.8 0.3 8.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain IncA PF04156.9 CDJ67508.1 - 0.076 12.6 16.7 0.084 12.4 11.5 1.1 1 0 0 1 1 1 0 IncA protein Lipase_GDSL_3 PF14606.1 CDJ67508.1 - 0.09 12.5 0.7 0.1 12.3 0.5 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family BBS1 PF14779.1 CDJ67508.1 - 0.13 11.1 0.8 0.15 11.0 0.5 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DUF4355 PF14265.1 CDJ67508.1 - 0.18 11.7 9.2 0.21 11.5 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Tho2 PF11262.3 CDJ67508.1 - 0.22 10.5 2.7 0.19 10.7 1.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4140 PF13600.1 CDJ67508.1 - 0.33 11.4 7.1 0.41 11.1 4.9 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Exonuc_VII_L PF02601.10 CDJ67508.1 - 0.42 9.7 6.6 0.4 9.8 4.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Med15 PF09606.5 CDJ67508.1 - 0.48 8.5 33.0 0.44 8.6 22.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF775 PF05603.7 CDJ67508.1 - 0.49 9.8 5.7 0.48 9.9 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PAT1 PF09770.4 CDJ67508.1 - 0.57 8.3 24.0 0.57 8.3 16.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ67508.1 - 0.88 9.8 9.6 0.92 9.8 6.6 1.1 1 0 0 1 1 1 0 AAA domain HlyD_2 PF12700.2 CDJ67508.1 - 0.95 8.5 6.0 0.88 8.6 4.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF945 PF06097.6 CDJ67508.1 - 0.97 8.1 9.4 1.2 7.8 6.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) DUF3573 PF12097.3 CDJ67508.1 - 1.1 7.8 7.5 1.1 7.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DEDD_Tnp_IS110 PF01548.12 CDJ67508.1 - 1.2 8.8 5.5 1.8 8.2 3.8 1.2 1 0 0 1 1 1 0 Transposase DUF3373 PF11853.3 CDJ67508.1 - 1.4 7.4 8.5 1.4 7.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4407 PF14362.1 CDJ67508.1 - 1.4 7.8 10.2 1.5 7.7 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GPO PF05929.6 CDJ67508.1 - 2.2 7.4 8.4 2.1 7.4 5.8 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2968 PF11180.3 CDJ67508.1 - 2.3 7.5 23.9 2.4 7.4 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Suf PF05843.9 CDJ67508.1 - 3.2 7.4 11.5 3.3 7.3 8.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3886 PF13025.1 CDJ67508.1 - 3.5 7.6 15.1 5.4 7.0 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF106 PF01956.11 CDJ67508.1 - 3.7 7.0 6.0 4 6.9 4.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DivIC PF04977.10 CDJ67508.1 - 3.8 7.0 17.3 6.5 6.3 12.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4557 PF15101.1 CDJ67508.1 - 4.1 7.1 13.7 4.2 7.1 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Spc24 PF08286.6 CDJ67508.1 - 4.3 7.0 9.8 5.6 6.7 6.8 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Serinc PF03348.10 CDJ67508.1 - 4.8 5.7 5.5 4.6 5.8 3.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 CDJ67508.1 - 5.2 4.6 25.7 5 4.6 17.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex14_N PF04695.8 CDJ67508.1 - 5.2 7.1 11.9 6.1 6.9 8.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1800 PF08811.6 CDJ67508.1 - 5.8 5.7 13.0 6.6 5.5 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) YfhO PF09586.5 CDJ67508.1 - 8.3 4.2 8.0 9.2 4.1 5.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO LigT_PEase PF02834.11 CDJ67508.1 - 8.7 6.4 6.1 54 3.8 3.2 2.2 1 1 1 2 2 2 0 LigT like Phosphoesterase zf-CCHC PF00098.18 CDJ67509.1 - 3.1e-05 23.6 10.5 0.0033 17.2 0.9 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ67509.1 - 0.006 16.2 2.3 0.033 13.9 0.0 2.6 1 1 1 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.12 CDJ67509.1 - 0.061 13.4 0.0 0.27 11.3 0.0 2.0 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC_6 PF15288.1 CDJ67509.1 - 0.061 13.0 0.1 0.061 13.0 0.1 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ67509.1 - 0.15 11.7 4.4 2.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ67509.1 - 0.15 12.0 7.2 0.76 9.8 5.0 2.0 1 1 0 1 1 1 0 DnaJ central domain Zn_Tnp_IS1595 PF12760.2 CDJ67509.1 - 1 9.2 7.2 2.6 7.9 1.0 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain rve PF00665.21 CDJ67510.1 - 1.6e-19 70.1 0.0 2.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ67510.1 - 0.005 16.3 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DUF2413 PF10310.4 CDJ67511.1 - 0.38 9.5 2.9 0.44 9.3 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Endostatin PF06482.6 CDJ67512.1 - 0.055 12.8 0.1 0.082 12.2 0.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SF-assemblin PF06705.6 CDJ67513.1 - 1.6e-41 142.1 16.0 1.7e-41 141.9 11.1 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Atg14 PF10186.4 CDJ67513.1 - 0.11 11.4 12.0 0.14 11.0 8.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 CDJ67513.1 - 0.27 10.2 19.5 0.56 9.2 12.0 2.1 1 1 1 2 2 2 0 Tropomyosin DUF3584 PF12128.3 CDJ67513.1 - 0.29 8.4 17.8 0.34 8.1 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 CDJ67513.1 - 0.45 10.6 6.5 0.24 11.5 1.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF641 PF04859.7 CDJ67513.1 - 1 9.1 9.3 0.93 9.2 4.4 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BTV_NS2 PF04514.7 CDJ67513.1 - 1.1 8.0 5.9 1.4 7.6 4.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4611 PF15387.1 CDJ67513.1 - 1.2 9.3 6.0 0.16 12.1 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) G-gamma PF00631.17 CDJ67513.1 - 1.9 8.2 4.3 5 6.9 3.0 1.7 1 0 0 1 1 1 0 GGL domain P4Ha_N PF08336.6 CDJ67513.1 - 2.6 7.8 8.3 7.2 6.4 1.1 3.0 2 1 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Mnd1 PF03962.10 CDJ67513.1 - 4.3 6.9 14.8 29 4.2 10.3 2.0 1 1 0 1 1 1 0 Mnd1 family DUF1003 PF06210.6 CDJ67513.1 - 8.2 6.3 10.7 3 7.8 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) HAUS6_N PF14661.1 CDJ67514.1 - 0.004 16.5 6.4 0.0045 16.3 4.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Metal_resist PF13801.1 CDJ67514.1 - 0.0054 16.7 8.1 0.014 15.3 5.6 1.7 1 1 0 1 1 1 1 Heavy-metal resistance mRNA_cap_C PF03919.10 CDJ67514.1 - 0.057 13.7 1.5 0.075 13.3 1.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain DUF2089 PF09862.4 CDJ67514.1 - 0.068 12.9 0.9 0.082 12.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Thioredoxin_8 PF13905.1 CDJ67514.1 - 0.11 12.6 0.4 0.15 12.2 0.3 1.2 1 0 0 1 1 1 0 Thioredoxin-like DUF1840 PF08895.6 CDJ67514.1 - 0.13 12.3 5.4 0.16 11.9 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Suf PF05843.9 CDJ67514.1 - 0.79 9.3 8.0 0.86 9.2 5.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) APG6 PF04111.7 CDJ67514.1 - 1.2 8.1 11.8 1.2 8.1 8.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 CDJ67514.1 - 2.5 6.2 12.7 2.5 6.2 8.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4557 PF15101.1 CDJ67514.1 - 2.7 7.7 11.5 2.8 7.7 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_23 PF13476.1 CDJ67514.1 - 5.5 7.2 16.7 6.3 7.0 11.6 1.0 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CDJ67514.1 - 6.4 4.5 8.4 6.5 4.4 5.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ER PF01133.12 CDJ67515.1 - 4.7e-28 96.9 0.0 7.7e-28 96.2 0.0 1.3 1 0 0 1 1 1 1 Enhancer of rudimentary DUF2029 PF09594.5 CDJ67515.1 - 0.0041 16.6 14.8 0.0041 16.6 10.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) Tryp_alpha_amyl PF00234.17 CDJ67515.1 - 0.021 15.0 7.7 2.8 8.2 3.2 2.3 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family DUF2681 PF10883.3 CDJ67515.1 - 0.88 9.8 8.1 2.4 8.4 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Activator_LAG-3 PF11498.3 CDJ67515.1 - 1.2 7.7 19.8 4.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SNF2_N PF00176.18 CDJ67516.1 - 8.1e-09 34.6 0.1 8.9e-05 21.4 0.0 3.2 3 0 0 3 3 3 2 SNF2 family N-terminal domain CDI PF02234.14 CDJ67516.1 - 3.5 7.4 4.6 12 5.8 3.2 2.0 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor SMC_N PF02463.14 CDJ67519.1 - 3.9e-09 36.0 0.6 4.5e-09 35.8 0.4 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CDJ67519.1 - 1.9e-07 31.6 10.8 2.9e-06 27.7 7.5 2.1 1 1 0 1 1 1 1 AAA domain CDK2AP PF09806.4 CDJ67519.1 - 0.00091 19.5 5.0 0.001 19.3 3.5 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CDJ67519.1 - 0.0035 16.8 12.2 0.0053 16.2 8.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 CDJ67519.1 - 0.0042 17.1 3.5 0.0055 16.7 2.4 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Chorion_2 PF03964.10 CDJ67519.1 - 0.0045 17.5 3.0 0.0073 16.8 2.1 1.4 1 0 0 1 1 1 1 Chorion family 2 AAA_29 PF13555.1 CDJ67519.1 - 0.0081 15.6 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PH_5 PF15405.1 CDJ67519.1 - 0.025 14.5 1.1 0.035 14.0 0.8 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Period_C PF12114.3 CDJ67519.1 - 0.028 14.0 8.0 0.043 13.4 5.6 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF789 PF05623.7 CDJ67519.1 - 0.033 13.6 2.6 0.042 13.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Aminotran_1_2 PF00155.16 CDJ67519.1 - 0.04 12.8 2.1 0.05 12.5 1.5 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II OATP PF03137.15 CDJ67519.1 - 0.057 11.4 1.6 0.076 11.0 1.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Corona_nucleoca PF00937.13 CDJ67519.1 - 0.077 11.9 5.0 0.091 11.6 3.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3446 PF11928.3 CDJ67519.1 - 0.58 10.3 9.3 1.1 9.5 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Ndc80_HEC PF03801.8 CDJ67519.1 - 1.8 7.9 6.6 2.8 7.3 4.6 1.2 1 0 0 1 1 1 0 HEC/Ndc80p family MSA-2c PF12238.3 CDJ67519.1 - 4.7 6.8 8.1 7.2 6.2 5.6 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Beta-lactamase PF00144.19 CDJ67520.1 - 0.025 13.5 0.2 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Beta-lactamase PSRT PF07636.6 CDJ67520.1 - 0.029 13.8 3.7 0.051 13.0 2.6 1.4 1 0 0 1 1 1 0 PSRT MCPVI PF02993.9 CDJ67520.1 - 1.7 8.7 6.9 1.9 8.5 4.8 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Herpes_TAF50 PF03326.8 CDJ67520.1 - 2.8 6.7 15.3 2.9 6.7 10.6 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) CAP_N PF01213.14 CDJ67520.1 - 3.5 6.8 6.2 3.8 6.7 4.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Trypan_glycop PF00913.14 CDJ67520.1 - 3.6 6.4 14.1 4.5 6.0 9.8 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) CDV3 PF15359.1 CDJ67520.1 - 5.4 7.1 7.7 6.9 6.7 5.0 1.4 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 Calsarcin PF05556.6 CDJ67520.1 - 9.8 5.3 7.2 11 5.1 5.0 1.1 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) TFIIF_alpha PF05793.7 CDJ67522.1 - 0.013 13.8 4.2 0.014 13.7 2.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BOP1NT PF08145.7 CDJ67522.1 - 1.7 8.2 11.5 1.9 8.1 7.9 1.0 1 0 0 1 1 1 0 BOP1NT (NUC169) domain ACC_epsilon PF13822.1 CDJ67522.1 - 4.2 7.8 16.0 0.44 10.9 1.3 2.5 1 1 1 2 2 2 0 Acyl-CoA carboxylase epsilon subunit AAA_23 PF13476.1 CDJ67522.1 - 9.9 6.4 8.8 11 6.2 6.1 1.1 1 0 0 1 1 1 0 AAA domain rve PF00665.21 CDJ67523.1 - 1.6e-18 66.9 0.0 3.7e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDJ67523.1 - 0.0092 15.3 0.3 0.018 14.4 0.2 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_3 PF13456.1 CDJ67523.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like rve_3 PF13683.1 CDJ67523.1 - 0.23 10.9 1.8 0.42 10.1 0.1 2.3 3 0 0 3 3 3 0 Integrase core domain Chorion_2 PF03964.10 CDJ67524.1 - 0.0076 16.7 3.4 0.0076 16.7 2.4 4.3 2 1 1 3 3 3 1 Chorion family 2 ETRAMP PF09716.5 CDJ67524.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.4 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) AMOP PF03782.12 CDJ67524.1 - 0.51 10.3 3.3 0.32 10.9 0.2 1.9 2 0 0 2 2 2 0 AMOP domain ATG16 PF08614.6 CDJ67524.1 - 7.6 6.3 12.5 0.76 9.5 0.8 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CBM_20 PF00686.14 CDJ67525.1 - 2.5e-16 59.0 0.0 3.9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain RAP1 PF07218.6 CDJ67525.1 - 3.2 5.7 7.0 4.3 5.2 4.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PIP5K PF01504.13 CDJ67528.1 - 0.34 9.9 13.7 0.014 14.5 3.8 2.7 2 1 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase Spt20 PF12090.3 CDJ67528.1 - 1.9 7.8 30.5 1.1 8.6 2.0 3.3 3 0 0 3 3 3 0 Spt20 family DUF4647 PF15504.1 CDJ67528.1 - 7.2 5.3 25.0 2.5 6.8 2.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4647) DUF2029 PF09594.5 CDJ67529.1 - 0.0025 17.3 2.7 0.0033 16.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) Ribosomal_60s PF00428.14 CDJ67529.1 - 0.009 16.3 22.2 0.12 12.8 3.4 2.1 2 0 0 2 2 2 2 60s Acidic ribosomal protein Pex14_N PF04695.8 CDJ67529.1 - 0.024 14.6 13.7 0.03 14.3 9.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.3 CDJ67529.1 - 0.063 11.8 1.5 0.066 11.7 1.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RskA PF10099.4 CDJ67529.1 - 0.063 13.0 25.3 0.084 12.5 7.0 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2217 PF10265.4 CDJ67529.1 - 0.21 10.3 3.0 0.23 10.2 2.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Helicase_IV_N PF12462.3 CDJ67529.1 - 0.34 10.5 10.4 0.35 10.4 7.2 1.1 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Med15 PF09606.5 CDJ67529.1 - 1.3 7.0 24.5 1.5 6.9 17.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-S31 PF15433.1 CDJ67529.1 - 3.1 7.1 9.3 3.6 6.9 6.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PAT1 PF09770.4 CDJ67529.1 - 4.1 5.5 23.6 4.5 5.3 16.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDJ67529.1 - 6.4 6.5 12.2 7.2 6.3 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4367 PF14285.1 CDJ67529.1 - 6.5 6.0 0.0 6.5 6.0 0.0 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF4367) Phage_H_T_join PF05521.6 CDJ67530.1 - 0.022 15.0 2.1 0.028 14.6 1.4 1.2 1 0 0 1 1 1 0 Phage head-tail joining protein CAF-1_p150 PF11600.3 CDJ67530.1 - 0.056 12.8 15.1 0.067 12.5 10.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Guanylin PF02058.10 CDJ67530.1 - 0.53 10.3 3.8 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Guanylin precursor DUF1675 PF07897.6 CDJ67530.1 - 0.59 9.9 15.7 0.69 9.7 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SR-25 PF10500.4 CDJ67530.1 - 1.9 7.8 28.9 8.1 5.8 20.1 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.7 CDJ67530.1 - 3 7.6 8.0 3.1 7.6 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 CDJ67530.1 - 9 5.3 13.6 10 5.1 9.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain PIP5K PF01504.13 CDJ67531.1 - 8.4e-24 84.0 3.7 4.1e-17 62.1 0.0 2.7 2 1 0 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase PT PF04886.7 CDJ67531.1 - 0.093 12.0 0.2 0.093 12.0 0.1 4.0 3 1 0 3 3 3 0 PT repeat Spt20 PF12090.3 CDJ67531.1 - 0.18 11.1 5.1 0.28 10.5 3.5 1.3 1 0 0 1 1 1 0 Spt20 family DUF4557 PF15101.1 CDJ67531.1 - 0.26 11.1 6.7 0.39 10.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 CDJ67531.1 - 0.63 7.6 14.5 0.76 7.3 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RAB3GAP2_N PF14655.1 CDJ67531.1 - 1.7 7.5 5.8 3.7 6.4 2.6 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BAF1_ABF1 PF04684.8 CDJ67531.1 - 2 7.1 12.5 2.5 6.8 8.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor LCD1 PF09798.4 CDJ67531.1 - 3.5 5.5 12.2 4.8 5.0 8.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Asp_protease_2 PF13650.1 CDJ67532.1 - 2.9e-09 37.2 0.0 8.2e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CDJ67532.1 - 9.4e-08 32.0 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CDJ67532.1 - 3.3e-06 26.8 0.0 7.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ67532.1 - 0.00033 20.5 0.0 0.001 18.9 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 CDJ67532.1 - 0.0015 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 CDJ67532.1 - 0.032 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease His_Phos_1 PF00300.17 CDJ67533.1 - 0.0011 19.0 1.0 0.0026 17.8 0.7 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1635 PF07795.6 CDJ67533.1 - 0.061 12.6 4.0 0.09 12.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Late_protein_L1 PF00500.13 CDJ67533.1 - 0.069 11.6 1.0 0.088 11.3 0.7 1.1 1 0 0 1 1 1 0 L1 (late) protein Dehydrin PF00257.14 CDJ67533.1 - 0.17 12.2 2.3 0.22 11.8 1.6 1.1 1 0 0 1 1 1 0 Dehydrin Kei1 PF08552.6 CDJ67533.1 - 0.17 11.5 0.7 0.25 11.0 0.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SR-25 PF10500.4 CDJ67533.1 - 0.22 10.9 8.9 0.3 10.5 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4557 PF15101.1 CDJ67533.1 - 0.28 10.9 3.8 0.37 10.5 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) APC_CDC26 PF10471.4 CDJ67533.1 - 4.9 7.9 9.9 9.7 7.0 6.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DNA_pol3_a_NII PF11490.3 CDJ67533.1 - 5.2 6.7 7.6 8.5 6.0 5.1 1.5 1 1 0 1 1 1 0 DNA polymerase III polC-type N-terminus II zf-CCHC PF00098.18 CDJ67534.1 - 0.0029 17.4 0.7 0.0062 16.4 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDJ67534.1 - 0.071 12.6 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 CDJ67535.1 - 2.2e-17 63.1 0.0 4.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDJ67535.1 - 4.3e-14 52.6 0.0 1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDJ67535.1 - 0.014 14.8 0.9 0.028 13.8 0.6 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger ATP-synt_ab PF00006.20 CDJ67536.1 - 2.5e-67 226.5 0.1 3e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 CDJ67536.1 - 0.025 14.4 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 CDJ67536.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RAB3GAP2_N PF14655.1 CDJ67537.1 - 0.035 13.1 2.9 0.045 12.7 2.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PgaD PF13994.1 CDJ67537.1 - 0.06 12.8 0.2 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 PgaD-like protein TraT PF05818.7 CDJ67537.1 - 0.56 9.5 6.3 0.61 9.4 3.9 1.3 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Dehydrin PF00257.14 CDJ67537.1 - 2.2 8.5 5.0 2.3 8.5 2.8 1.4 1 1 0 1 1 1 0 Dehydrin DUF3597 PF12200.3 CDJ67537.1 - 3 8.2 16.6 1.4 9.3 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Pex14_N PF04695.8 CDJ67538.1 - 7.1 6.6 13.4 17 5.4 7.1 2.5 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RE_CfrBI PF09516.5 CDJ67539.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 CfrBI restriction endonuclease DUF3563 PF12086.3 CDJ67539.1 - 0.12 12.0 2.7 0.18 11.5 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3563) DUF572 PF04502.8 CDJ67539.1 - 2.2 7.4 16.3 3.4 6.7 11.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.4 CDJ67539.1 - 2.5 6.2 33.4 3.1 5.9 23.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G0-G1_switch_2 PF15103.1 CDJ67539.1 - 8.3 6.7 12.9 1.3 9.2 2.5 2.7 2 0 0 2 2 2 0 G0/G1 switch protein 2 Fasciclin PF02469.17 CDJ67540.1 - 5e-10 39.4 1.6 0.00014 21.8 0.0 3.6 2 1 0 2 2 2 2 Fasciclin domain Suf PF05843.9 CDJ67540.1 - 0.00037 20.3 5.2 0.00037 20.3 3.6 2.8 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) SGT1 PF07093.6 CDJ67540.1 - 0.0067 14.8 10.9 0.03 12.7 0.7 2.2 2 0 0 2 2 2 2 SGT1 protein Ycf1 PF05758.7 CDJ67540.1 - 0.18 9.4 10.8 0.043 11.5 0.2 2.0 2 0 0 2 2 2 0 Ycf1 Neur_chan_memb PF02932.11 CDJ67540.1 - 0.3 10.9 11.7 1.9 8.3 0.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF966 PF06136.8 CDJ67540.1 - 0.69 9.2 16.5 1.1 8.6 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF966) SPX PF03105.14 CDJ67540.1 - 2.4 7.8 17.2 2.1 8.0 4.1 2.2 2 0 0 2 2 2 0 SPX domain TMEM51 PF15345.1 CDJ67541.1 - 0.019 14.6 2.3 0.019 14.6 1.6 2.5 2 1 1 3 3 3 0 Transmembrane protein 51 Cwf_Cwc_15 PF04889.7 CDJ67541.1 - 2.3 7.8 26.9 0.17 11.6 6.8 2.2 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PRP38_assoc PF12871.2 CDJ67541.1 - 4.5 7.8 16.5 0.87 10.1 4.4 2.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term UL40 PF10682.4 CDJ67542.1 - 1.9 7.9 3.7 0.6 9.5 0.5 1.6 2 0 0 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 Glyco_hydro_9 PF00759.14 CDJ67542.1 - 4.2 6.1 7.8 0.23 10.3 1.4 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 SSP160 PF06933.6 CDJ67542.1 - 7.5 4.3 10.1 10 3.9 7.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 P12 PF12669.2 CDJ67543.1 - 0.6 10.3 10.3 2.6 8.3 0.9 4.7 2 1 0 2 2 2 0 Virus attachment protein p12 family DUF4367 PF14285.1 CDJ67544.1 - 0.41 9.9 0.1 0.41 9.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4367) DUF3371 PF11851.3 CDJ67544.1 - 6.2 7.5 17.3 0.94 10.1 5.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) IncA PF04156.9 CDJ67545.1 - 0.00015 21.3 4.0 0.00028 20.5 2.7 1.4 1 0 0 1 1 1 1 IncA protein Herpes_glycop PF01528.11 CDJ67545.1 - 0.34 9.5 2.3 0.39 9.3 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M TFIIA PF03153.8 CDJ67545.1 - 0.6 9.9 8.6 0.62 9.9 5.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3450 PF11932.3 CDJ67545.1 - 1.9 7.6 14.4 2.6 7.2 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MSP1_C PF07462.6 CDJ67545.1 - 5.8 5.1 9.0 6.4 5.0 6.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4589 PF15252.1 CDJ67545.1 - 7.2 6.3 8.3 16 5.2 5.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) DUF4263 PF14082.1 CDJ67546.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Aldedh PF00171.17 CDJ67549.1 - 6.2e-07 28.1 0.1 1.3e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Aldehyde dehydrogenase family CDK2AP PF09806.4 CDJ67549.1 - 0.0031 17.7 7.5 0.0031 17.7 5.2 2.4 2 1 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein Spt20 PF12090.3 CDJ67549.1 - 0.023 14.0 0.3 0.023 14.0 0.2 1.5 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.5 CDJ67549.1 - 0.057 11.6 20.3 0.08 11.1 14.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 CDJ67549.1 - 0.26 11.1 2.2 0.5 10.2 1.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Secretin_N_2 PF07655.8 CDJ67549.1 - 1.5 9.2 18.2 2.3 8.6 0.0 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain PHD_3 PF13922.1 CDJ67549.1 - 1.9 8.7 6.8 7.7 6.8 4.7 2.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DivIC PF04977.10 CDJ67549.1 - 6.9 6.2 9.2 12 5.4 6.4 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4602 PF15375.1 CDJ67550.1 - 0.053 13.5 18.7 0.043 13.8 2.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4602) Calici_coat_C PF08435.6 CDJ67550.1 - 0.083 12.1 2.8 1.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal Amdo_NSP PF12475.3 CDJ67550.1 - 0.82 9.6 2.4 13 5.7 0.3 2.5 2 0 0 2 2 2 0 Amdovirus non-structural protein FCP1_C PF09309.5 CDJ67550.1 - 3.2 6.9 28.1 0.9 8.7 2.7 2.1 2 0 0 2 2 2 0 FCP1, C-terminal Band_3_cyto PF07565.8 CDJ67550.1 - 4.4 6.7 10.6 0.26 10.7 2.1 2.1 1 1 1 2 2 2 0 Band 3 cytoplasmic domain IER PF05760.7 CDJ67550.1 - 5.4 6.8 22.7 7.1 6.4 10.6 2.1 2 0 0 2 2 2 0 Immediate early response protein (IER) PAT1 PF09770.4 CDJ67550.1 - 5.6 5.0 34.0 7.2 4.7 23.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ERM PF00769.14 CDJ67550.1 - 7.7 5.9 24.2 0.53 9.7 7.7 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family rve PF00665.21 CDJ67551.1 - 1.8e-05 24.8 0.0 6.2e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 CDJ67551.1 - 0.00073 18.8 2.6 0.0013 18.1 1.8 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Scramblase PF03803.10 CDJ67551.1 - 0.058 12.4 0.0 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Scramblase FAM92 PF06730.6 CDJ67551.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 FAM92 protein UPF0051 PF01458.12 CDJ67552.1 - 1.4e-48 165.3 0.0 1.1e-47 162.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family (UPF0051) TMEM210 PF15195.1 CDJ67553.1 - 0.64 10.1 2.8 1.9 8.6 1.9 1.8 1 0 0 1 1 1 0 TMEM210 family Peptidase_S8 PF00082.17 CDJ67554.1 - 6.2e-45 153.5 5.1 6.2e-45 153.5 3.6 1.9 2 0 0 2 2 2 1 Subtilase family DUF308 PF03729.8 CDJ67554.1 - 0.082 12.9 0.2 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF4381 PF14316.1 CDJ67555.1 - 0.00027 21.0 5.3 0.064 13.3 0.1 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF4381) DUF1180 PF06679.7 CDJ67555.1 - 0.0023 17.8 2.8 0.0023 17.8 1.9 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1180) DUF2975 PF11188.3 CDJ67556.1 - 0.081 12.6 0.6 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Herpes_gE PF02480.11 CDJ67556.1 - 0.24 9.5 0.8 0.39 8.9 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E SIT PF15330.1 CDJ67556.1 - 0.57 10.3 4.3 0.13 12.3 0.6 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT zf-RING_2 PF13639.1 CDJ67557.1 - 1.9e-10 40.3 12.2 4e-10 39.3 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDJ67557.1 - 3.4e-07 30.2 6.0 6.9e-07 29.2 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDJ67557.1 - 4.2e-06 26.6 6.4 1e-05 25.4 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDJ67557.1 - 0.00014 21.4 7.9 0.00028 20.4 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDJ67557.1 - 0.00026 20.5 6.1 0.00061 19.3 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ67557.1 - 0.0024 17.5 9.2 0.0048 16.6 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CDJ67557.1 - 0.0043 16.7 1.2 0.0097 15.6 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger CDC48_2 PF02933.12 CDJ67557.1 - 0.037 13.6 0.3 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 zf-Apc11 PF12861.2 CDJ67557.1 - 0.049 13.4 4.8 0.093 12.5 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CDJ67557.1 - 4.2 7.0 8.3 9 5.9 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 CDJ67557.1 - 7 6.4 11.1 0.55 9.9 0.8 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 EMG1 PF03587.9 CDJ67560.1 - 3.8e-41 140.5 0.1 4.9e-41 140.2 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DEAD PF00270.24 CDJ67561.1 - 5.5e-32 110.5 0.0 2.6e-22 79.0 0.0 2.8 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ67561.1 - 3.1e-24 84.6 0.0 5.9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDJ67561.1 - 3.2e-05 23.8 0.0 0.00022 21.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_transf_28 PF03033.15 CDJ67561.1 - 0.03 14.1 0.1 0.14 11.8 0.0 2.2 3 0 0 3 3 3 0 Glycosyltransferase family 28 N-terminal domain AAA_22 PF13401.1 CDJ67561.1 - 0.12 12.5 0.0 6.8 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain Peptidase_M41 PF01434.13 CDJ67562.1 - 2.3e-57 193.9 0.1 6.9e-57 192.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CDJ67562.1 - 9.9e-42 142.2 0.0 2e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CDJ67562.1 - 1.8e-05 25.5 0.0 5.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDJ67562.1 - 0.0003 20.9 0.1 0.027 14.6 0.1 2.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CDJ67562.1 - 0.0004 19.2 0.0 0.00063 18.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 CDJ67562.1 - 0.0014 18.3 0.0 0.0051 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDJ67562.1 - 0.003 17.5 0.2 0.003 17.5 0.1 3.2 4 1 0 4 4 4 1 AAA ATPase domain Zeta_toxin PF06414.7 CDJ67562.1 - 0.0032 16.5 0.1 0.029 13.4 0.0 2.2 1 1 1 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 CDJ67562.1 - 0.0077 15.6 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 CDJ67562.1 - 0.0085 15.1 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CDJ67562.1 - 0.013 15.2 0.4 0.013 15.2 0.3 3.0 4 0 0 4 4 4 0 Part of AAA domain AAA_33 PF13671.1 CDJ67562.1 - 0.014 15.3 1.3 0.031 14.1 0.0 2.4 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 CDJ67562.1 - 0.021 13.9 0.5 0.11 11.6 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CDJ67562.1 - 0.033 14.4 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CDJ67562.1 - 0.062 12.6 1.3 0.21 10.9 0.5 2.1 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 CDJ67562.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 CDJ67562.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rho_Binding PF08912.6 CDJ67562.1 - 4.1 7.7 7.7 1.2 9.4 2.8 2.1 2 0 0 2 2 1 0 Rho Binding Glyoxalase_2 PF12681.2 CDJ67563.1 - 9.5e-13 48.7 0.0 1.5e-07 31.9 0.0 3.3 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase PF00903.20 CDJ67563.1 - 2.5e-12 46.8 0.0 1e-08 35.2 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 CDJ67563.1 - 1.3e-05 25.1 0.0 0.04 13.9 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DGF-1_C PF11040.3 CDJ67564.1 - 0.034 14.0 2.6 0.13 12.1 1.8 2.0 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DGF-1_C PF11040.3 CDJ67565.1 - 0.013 15.4 2.4 0.031 14.1 1.7 1.6 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CENP-B_dimeris PF09026.5 CDJ67566.1 - 0.18 12.0 2.6 0.34 11.1 1.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ABC_tran PF00005.22 CDJ67567.1 - 4.3e-24 85.3 0.0 6.9e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CDJ67567.1 - 3.7e-18 65.4 16.9 9e-18 64.2 11.7 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CDJ67567.1 - 6.1e-10 38.6 13.0 9.2e-10 38.0 9.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 CDJ67567.1 - 7.4e-09 35.9 0.0 3.4e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDJ67567.1 - 7.3e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 CDJ67567.1 - 0.00023 20.1 5.2 0.00033 19.6 3.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.1 CDJ67567.1 - 0.00058 19.3 0.3 0.0013 18.2 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CDJ67567.1 - 0.00082 19.4 0.1 0.002 18.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CDJ67567.1 - 0.004 16.5 0.2 0.012 15.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDJ67567.1 - 0.0072 17.1 0.0 0.014 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CDJ67567.1 - 0.0072 16.2 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 CDJ67567.1 - 0.0092 16.2 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CDJ67567.1 - 0.01 14.6 0.2 0.024 13.4 0.1 1.5 1 0 0 1 1 1 0 ArgK protein DUF87 PF01935.12 CDJ67567.1 - 0.012 15.4 0.3 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_15 PF13175.1 CDJ67567.1 - 0.014 14.4 0.0 0.57 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 CDJ67567.1 - 0.046 13.6 0.1 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CDJ67567.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 CDJ67567.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CDJ67567.1 - 0.13 11.6 0.5 0.25 10.7 0.4 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 CDJ67567.1 - 0.14 12.3 0.1 0.75 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CDJ67567.1 - 0.15 11.8 0.0 0.4 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CDJ67567.1 - 0.16 11.4 0.1 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-met PF12874.2 CDJ67568.1 - 6.1e-07 29.4 1.5 1.2e-06 28.5 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 CDJ67568.1 - 0.058 12.9 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PPR PF01535.15 CDJ67569.1 - 2e-14 52.4 1.5 0.00066 19.4 0.1 6.3 7 0 0 7 7 7 2 PPR repeat PPR_2 PF13041.1 CDJ67569.1 - 4e-13 49.1 0.1 3.7e-06 26.7 0.0 4.5 3 1 2 5 5 5 2 PPR repeat family PPR_3 PF13812.1 CDJ67569.1 - 2e-10 40.1 29.9 0.0057 16.8 0.0 9.6 10 0 0 10 10 10 4 Pentatricopeptide repeat domain Imm16 PF15565.1 CDJ67569.1 - 0.027 14.3 0.3 0.081 12.7 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 16 PrpF PF04303.8 CDJ67569.1 - 0.11 11.1 2.0 0.24 10.0 1.4 1.5 1 0 0 1 1 1 0 PrpF protein Ig_Tie2_1 PF10430.4 CDJ67569.1 - 0.23 11.8 1.2 2.2 8.6 0.1 3.1 3 0 0 3 3 3 0 Tie-2 Ig-like domain 1 TPR_7 PF13176.1 CDJ67569.1 - 0.4 10.5 6.0 0.97 9.3 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Fes1 PF08609.5 CDJ67569.1 - 8.2 6.9 7.3 1 9.9 0.6 2.8 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Vac14_Fab1_bd PF12755.2 CDJ67570.1 - 1.4e-33 115.1 0.0 1.3e-29 102.4 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.3 CDJ67570.1 - 1.3e-17 63.5 0.7 2.1e-12 46.5 0.1 2.5 2 0 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.17 CDJ67570.1 - 4.9e-12 44.8 0.2 0.0047 16.9 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 CDJ67570.1 - 2.4e-05 24.4 7.8 0.039 14.2 0.2 5.4 3 1 2 5 5 5 3 HEAT repeats DUF2454 PF10521.4 CDJ67570.1 - 0.0034 16.4 2.1 0.24 10.3 0.2 3.7 5 0 0 5 5 5 1 Protein of unknown function (DUF2454) HEAT_EZ PF13513.1 CDJ67570.1 - 0.004 17.6 8.8 0.057 13.9 0.0 5.6 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 CDJ67570.1 - 0.0048 16.7 0.0 1.3 8.8 0.0 3.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 ubiquitin PF00240.18 CDJ67571.1 - 7.6e-35 118.1 0.4 1e-34 117.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CDJ67571.1 - 1.1e-30 104.9 10.6 1.8e-30 104.2 7.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CDJ67571.1 - 8e-21 73.5 0.5 1.2e-20 72.9 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDJ67571.1 - 1.1e-06 28.8 0.1 3.5e-06 27.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CDJ67571.1 - 0.00046 19.9 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing TUG-UBL1 PF11470.3 CDJ67571.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Rad60-SLD_2 PF13881.1 CDJ67571.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDJ67571.1 - 0.021 15.0 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 CDJ67571.1 - 0.23 11.3 1.9 1.4 8.7 1.0 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain U-box PF04564.10 CDJ67573.1 - 1.4e-18 66.5 0.0 2.9e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 CDJ67573.1 - 5.7e-15 54.7 5.3 2e-13 49.7 2.2 2.5 1 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 CDJ67573.1 - 9.7e-11 40.8 7.7 0.001 18.5 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ67573.1 - 5e-10 38.5 8.3 0.0069 16.2 1.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 CDJ67573.1 - 2.6e-07 30.6 1.1 4.4e-07 29.9 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CDJ67573.1 - 5.4e-07 29.4 6.3 2e-05 24.4 1.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ67573.1 - 3e-06 26.6 6.6 0.018 14.7 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ67573.1 - 5.1e-05 23.8 2.5 5.1e-05 23.8 1.7 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ67573.1 - 0.00038 20.2 3.3 0.0012 18.6 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ67573.1 - 0.0081 16.4 3.9 0.024 14.9 2.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ67573.1 - 0.013 15.6 0.8 0.41 10.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CDJ67573.1 - 0.29 11.1 6.7 2.2 8.3 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SR-25 PF10500.4 CDJ67573.1 - 0.36 10.2 0.0 0.36 10.2 0.0 3.2 2 1 1 3 3 2 0 Nuclear RNA-splicing-associated protein TPR_14 PF13428.1 CDJ67573.1 - 0.48 11.2 11.0 2.4 9.0 0.0 4.3 2 2 3 5 5 5 0 Tetratricopeptide repeat EGF_2 PF07974.8 CDJ67574.1 - 0.0051 16.9 34.8 0.0095 16.0 3.1 4.1 3 0 0 3 3 3 3 EGF-like domain CBM_19 PF03427.8 CDJ67576.1 - 0.14 11.9 0.2 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) FUSC PF04632.7 CDJ67576.1 - 0.63 8.3 4.0 0.67 8.3 2.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YmgB PF10798.3 CDJ67578.1 - 0.54 10.1 0.0 1.3 8.8 0.0 1.7 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR Radial_spoke_3 PF06098.6 CDJ67579.1 - 2.2e-05 23.6 11.2 2.2e-05 23.6 7.8 1.9 2 0 0 2 2 2 1 Radial spoke protein 3 DUF2335 PF10097.4 CDJ67579.1 - 0.38 10.4 0.0 0.38 10.4 0.0 4.2 4 0 0 4 4 4 0 Predicted membrane protein (DUF2335) Methyltrn_RNA_4 PF09936.4 CDJ67579.1 - 0.69 9.3 3.1 0.35 10.3 0.3 1.9 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase TRM13 PF05206.9 CDJ67580.1 - 4.7e-08 32.5 3.9 6.5e-05 22.2 0.0 3.7 4 0 0 4 4 4 2 Methyltransferase TRM13 zf-U11-48K PF05253.7 CDJ67580.1 - 4.2e-05 23.1 0.5 8e-05 22.2 0.4 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger FAD-oxidase_C PF02913.14 CDJ67581.1 - 1.7e-39 135.6 0.0 2.6e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CDJ67581.1 - 4.7e-33 113.6 0.3 8.2e-33 112.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain SNARE_assoc PF09335.6 CDJ67582.1 - 4.7e-15 55.8 8.7 4.7e-15 55.8 6.1 2.6 3 0 0 3 3 3 2 SNARE associated Golgi protein DUF3087 PF11286.3 CDJ67582.1 - 0.36 10.0 1.9 3 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Med15 PF09606.5 CDJ67583.1 - 0.0025 16.1 9.7 0.0025 16.1 6.7 4.1 2 1 2 5 5 5 2 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDJ67583.1 - 0.062 12.6 69.5 0.028 13.8 24.9 4.4 4 0 0 4 4 4 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MKT1_C PF12246.3 CDJ67584.1 - 1.2e-15 57.2 0.0 4.6e-15 55.2 0.0 2.0 2 1 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 CDJ67584.1 - 1.2e-07 31.7 0.0 3.8e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 XPG I-region MKT1_N PF12247.3 CDJ67584.1 - 2.5e-07 30.8 0.0 2.2e-06 27.8 0.0 2.5 3 0 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 CDJ67584.1 - 5.8e-07 29.7 0.0 1.3e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DUF4475 PF14753.1 CDJ67585.1 - 8.7e-26 90.6 12.3 5.7e-22 78.1 5.3 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4475) GD_AH_C PF04295.8 CDJ67585.1 - 0.024 13.3 4.3 0.26 9.8 0.9 2.3 2 0 0 2 2 2 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Glyco_tranf_2_4 PF13704.1 CDJ67585.1 - 0.16 12.3 0.3 0.16 12.3 0.2 2.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Spt20 PF12090.3 CDJ67585.1 - 0.16 11.2 14.9 0.073 12.4 1.1 2.8 3 0 0 3 3 3 0 Spt20 family Glycos_transf_1 PF00534.15 CDJ67586.1 - 0.073 12.4 0.3 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 Neur_chan_memb PF02932.11 CDJ67586.1 - 0.09 12.6 16.5 1.8 8.3 0.1 3.9 3 2 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region S1 PF00575.18 CDJ67588.1 - 0.00059 19.8 0.0 1.6 8.9 0.0 5.6 7 0 0 7 7 7 1 S1 RNA binding domain N6_N4_Mtase PF01555.13 CDJ67588.1 - 0.028 13.9 0.0 21 4.4 0.1 3.9 4 1 0 4 4 4 0 DNA methylase DUF1510 PF07423.6 CDJ67589.1 - 0.0022 17.3 14.2 0.0025 17.2 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Trp_oprn_chp PF09534.5 CDJ67589.1 - 0.017 14.7 2.4 0.02 14.5 1.7 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CD20 PF04103.10 CDJ67589.1 - 0.062 13.2 2.5 0.085 12.7 1.7 1.2 1 0 0 1 1 1 0 CD20-like family RIC3 PF15361.1 CDJ67589.1 - 0.078 13.2 13.8 0.098 12.8 9.6 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 OATP PF03137.15 CDJ67589.1 - 0.11 10.5 12.9 0.14 10.2 9.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2561 PF10812.3 CDJ67589.1 - 0.13 11.8 4.5 0.15 11.6 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) SprA-related PF12118.3 CDJ67589.1 - 0.21 10.8 38.7 0.21 10.8 26.9 1.1 1 0 0 1 1 1 0 SprA-related family FLO_LFY PF01698.11 CDJ67589.1 - 0.36 9.6 14.1 0.34 9.7 9.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 CDJ67589.1 - 0.57 9.9 14.6 0.56 9.9 10.1 1.0 1 0 0 1 1 1 0 DDHD domain Pap_E4 PF02711.9 CDJ67589.1 - 0.79 10.5 14.8 0.93 10.3 10.3 1.1 1 0 0 1 1 1 0 E4 protein AIF_C PF14721.1 CDJ67589.1 - 0.82 9.9 14.0 0.88 9.8 9.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ctr PF04145.10 CDJ67589.1 - 0.99 9.4 9.2 1.1 9.2 6.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family TMEM51 PF15345.1 CDJ67589.1 - 1.2 8.8 15.9 1.3 8.6 11.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 AMP-binding PF00501.23 CDJ67589.1 - 1.4 7.2 6.6 1.5 7.1 4.6 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Tim54 PF11711.3 CDJ67589.1 - 1.7 7.1 11.1 1.6 7.2 7.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Folate_carrier PF01770.13 CDJ67589.1 - 1.8 7.0 11.5 1.9 6.9 8.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier Shisa PF13908.1 CDJ67589.1 - 1.8 8.7 18.1 2.1 8.4 12.6 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CPSF100_C PF13299.1 CDJ67589.1 - 2 8.5 15.9 2.2 8.4 11.0 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Spore_coat_CotO PF14153.1 CDJ67589.1 - 2.2 7.6 24.3 2.3 7.6 16.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF3260 PF11658.3 CDJ67589.1 - 2.4 6.2 16.6 2.7 6.0 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) FAM176 PF14851.1 CDJ67589.1 - 2.4 7.8 8.5 2.7 7.6 5.9 1.2 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.7 CDJ67589.1 - 2.5 7.9 16.4 2.4 8.0 11.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 CDJ67589.1 - 2.5 7.7 11.8 2.7 7.6 8.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Baculo_PP31 PF05311.6 CDJ67589.1 - 2.6 7.2 19.3 2.7 7.1 13.4 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Prog_receptor PF02161.10 CDJ67589.1 - 2.6 6.7 14.2 2.7 6.7 9.9 1.0 1 0 0 1 1 1 0 Progesterone receptor Peptidase_U57 PF05582.7 CDJ67589.1 - 2.8 6.8 14.6 2.9 6.7 10.1 1.0 1 0 0 1 1 1 0 YabG peptidase U57 FHIPEP PF00771.15 CDJ67589.1 - 2.9 6.1 11.8 3.3 5.9 8.2 1.1 1 0 0 1 1 1 0 FHIPEP family Zip PF02535.17 CDJ67589.1 - 3.1 6.7 4.7 2.8 6.8 3.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cellulose_synt PF03552.9 CDJ67589.1 - 3.1 5.9 7.2 3 6.0 5.0 1.0 1 0 0 1 1 1 0 Cellulose synthase Helicase_RecD PF05127.9 CDJ67589.1 - 3.6 7.1 9.5 3.9 7.0 6.6 1.1 1 0 0 1 1 1 0 Helicase SpoVR PF04293.8 CDJ67589.1 - 3.6 5.8 15.6 3.4 5.9 10.8 1.0 1 0 0 1 1 1 0 SpoVR like protein NARP1 PF12569.3 CDJ67589.1 - 3.6 6.2 18.4 3.5 6.2 12.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.11 CDJ67589.1 - 3.7 7.3 12.3 4.1 7.2 8.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peroxin-13_N PF04088.8 CDJ67589.1 - 3.8 7.4 10.2 4.4 7.2 7.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region AUX_IAA PF02309.11 CDJ67589.1 - 4.1 7.0 14.6 4 7.1 10.2 1.0 1 0 0 1 1 1 0 AUX/IAA family AAA_23 PF13476.1 CDJ67589.1 - 4.2 7.6 24.6 4.2 7.6 17.0 1.1 1 0 0 1 1 1 0 AAA domain Mem_trans PF03547.13 CDJ67589.1 - 4.3 5.5 9.2 4.6 5.4 6.4 1.0 1 0 0 1 1 1 0 Membrane transport protein Dala_Dala_lig_N PF01820.16 CDJ67589.1 - 4.9 7.4 10.4 5.6 7.3 7.2 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus UPF0052 PF01933.13 CDJ67589.1 - 5 6.3 8.1 5.2 6.3 5.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Herpes_DNAp_acc PF04929.7 CDJ67589.1 - 5.1 5.9 12.7 5.1 5.9 8.8 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_S15 PF02129.13 CDJ67589.1 - 5.3 6.3 15.7 5.5 6.3 10.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PAT1 PF09770.4 CDJ67589.1 - 5.5 5.1 44.2 5.4 5.1 30.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 CDJ67589.1 - 5.9 6.4 30.8 6.5 6.2 21.3 1.1 1 0 0 1 1 1 0 IncA protein Serinc PF03348.10 CDJ67589.1 - 6.3 5.3 17.5 6.5 5.3 12.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pal1 PF08316.6 CDJ67589.1 - 6.4 7.2 9.0 6.7 7.1 6.2 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF2126 PF09899.4 CDJ67589.1 - 6.4 4.6 12.9 5.7 4.8 8.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Pex14_N PF04695.8 CDJ67589.1 - 7.3 6.6 28.3 8.5 6.4 19.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDJ67589.1 - 7.5 4.6 59.0 7 4.7 40.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S49_N PF08496.5 CDJ67589.1 - 8.6 6.1 17.6 9.9 5.9 12.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Band_3_cyto PF07565.8 CDJ67589.1 - 9.2 5.6 19.3 9.9 5.5 13.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ATAD4 PF15321.1 CDJ67589.1 - 9.7 7.2 16.9 14 6.7 11.7 1.4 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Kelch_2 PF07646.10 CDJ67591.1 - 0.011 15.4 0.1 5.2 6.9 0.0 2.4 1 1 1 2 2 2 0 Kelch motif Kelch_5 PF13854.1 CDJ67591.1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Herpes_UL87 PF03043.9 CDJ67591.1 - 0.24 9.7 7.8 0.36 9.1 5.4 1.4 1 1 0 1 1 1 0 Herpesvirus UL87 family Ndc1_Nup PF09531.5 CDJ67591.1 - 1.4 7.2 18.1 1.6 7.0 12.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GCC2_GCC3 PF07699.8 CDJ67592.1 - 9.4e-10 37.9 46.4 0.0035 16.8 3.8 6.9 2 2 6 8 8 8 8 GCC2 and GCC3 VASP_tetra PF08776.6 CDJ67593.1 - 0.35 10.2 3.1 1.3 8.3 0.2 2.6 1 1 1 2 2 2 0 VASP tetramerisation domain RRM_1 PF00076.17 CDJ67595.1 - 3e-14 52.4 0.0 4.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ67595.1 - 1.3e-11 44.3 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ67595.1 - 9.7e-08 31.7 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Str_synth PF03088.11 CDJ67596.1 - 5.7e-08 32.6 0.0 2.2e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.7 CDJ67596.1 - 0.0022 17.4 0.0 0.0078 15.6 0.0 1.9 3 0 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Methyltransf_11 PF08241.7 CDJ67597.1 - 1.6e-20 73.4 0.0 1.5e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ67597.1 - 5.1e-20 71.8 0.0 1.1e-19 70.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ67597.1 - 7.2e-19 68.4 0.1 9.6e-18 64.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ67597.1 - 7e-18 64.8 0.1 7.8e-17 61.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ67597.1 - 3.4e-17 62.4 0.0 6.6e-17 61.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CDJ67597.1 - 7.2e-14 51.5 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CDJ67597.1 - 2.5e-13 50.3 0.1 1.4e-12 47.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDJ67597.1 - 3.3e-12 46.0 0.1 7.3e-10 38.3 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CDJ67597.1 - 2.1e-09 37.4 0.0 5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDJ67597.1 - 2.1e-07 30.5 0.0 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 CDJ67597.1 - 0.00022 20.5 0.0 0.00086 18.6 0.0 1.7 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.14 CDJ67597.1 - 0.0014 18.2 0.0 0.0054 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 CDJ67597.1 - 0.0029 16.9 0.0 0.11 11.7 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 CDJ67597.1 - 0.0046 16.0 0.0 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 CDJ67597.1 - 0.0055 15.7 0.0 0.0087 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 CDJ67597.1 - 0.0065 15.8 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.14 CDJ67597.1 - 0.0085 16.0 0.1 0.04 13.8 0.1 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.6 CDJ67597.1 - 0.011 15.1 0.0 0.056 12.8 0.0 2.0 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 CDJ67597.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.8 CDJ67597.1 - 0.037 13.3 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_15 PF09445.5 CDJ67597.1 - 0.082 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 CDJ67597.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FimP PF09766.4 CDJ67600.1 - 0.047 12.7 3.5 0.06 12.4 2.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDJ67600.1 - 0.072 12.8 5.2 0.088 12.5 3.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_LMP2 PF07415.6 CDJ67600.1 - 0.093 11.3 6.1 0.14 10.6 4.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein PAT1 PF09770.4 CDJ67600.1 - 0.11 10.6 10.5 0.11 10.6 7.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDJ67600.1 - 0.11 11.8 11.9 0.17 11.2 8.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2201_N PF13203.1 CDJ67600.1 - 0.17 10.9 10.3 0.26 10.4 7.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 CDJ67600.1 - 0.22 11.3 5.4 0.3 10.9 3.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CDJ67600.1 - 0.35 9.6 2.9 0.46 9.2 2.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1675 PF07897.6 CDJ67600.1 - 1.8 8.3 12.4 2.5 7.8 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDHD PF02862.12 CDJ67600.1 - 2.7 7.7 7.5 4.1 7.1 5.2 1.3 1 0 0 1 1 1 0 DDHD domain Mito_fiss_reg PF05308.6 CDJ67600.1 - 2.9 7.2 13.6 2.2 7.5 5.9 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4175 PF13779.1 CDJ67600.1 - 3 5.4 15.7 4.7 4.7 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF605 PF04652.11 CDJ67600.1 - 5.8 6.2 21.6 9.5 5.5 15.0 1.3 1 1 0 1 1 1 0 Vta1 like Macoilin PF09726.4 CDJ67600.1 - 9.3 4.3 10.0 14 3.7 7.0 1.4 1 0 0 1 1 1 0 Transmembrane protein Nitroreductase PF00881.19 CDJ67602.1 - 0.007 16.2 0.4 0.0087 15.9 0.3 1.2 1 0 0 1 1 1 1 Nitroreductase family Spt20 PF12090.3 CDJ67602.1 - 0.015 14.6 5.3 0.018 14.4 3.7 1.2 1 0 0 1 1 1 0 Spt20 family PPK2 PF03976.9 CDJ67602.1 - 0.036 13.3 0.7 0.052 12.8 0.5 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Peptidase_U57 PF05582.7 CDJ67602.1 - 0.057 12.3 0.4 0.069 12.1 0.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 tRNA_synt_2f PF02092.12 CDJ67602.1 - 0.096 11.2 2.6 0.095 11.2 1.8 1.0 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit eIF_4EBP PF05456.6 CDJ67602.1 - 0.1 12.3 1.3 0.11 12.1 0.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF3043 PF11241.3 CDJ67602.1 - 0.15 11.6 0.9 0.16 11.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) RAB3GAP2_N PF14655.1 CDJ67602.1 - 0.33 9.8 5.0 0.34 9.8 3.5 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDJ67602.1 - 0.45 10.1 7.3 0.51 10.0 5.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ67602.1 - 1.7 6.7 24.4 1.7 6.7 16.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDJ67602.1 - 2.7 6.7 12.7 3.1 6.5 8.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 CDJ67602.1 - 4.2 5.4 21.4 4.2 5.4 14.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_2 PF13347.1 CDJ67603.1 - 4.8e-20 71.3 9.9 2.7e-14 52.4 0.7 2.0 2 0 0 2 2 2 2 MFS/sugar transport protein DUF2768 PF10966.3 CDJ67603.1 - 0.42 10.7 7.8 3.4 7.8 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2768) ABC2_membrane_3 PF12698.2 CDJ67603.1 - 0.7 8.8 5.4 0.94 8.4 3.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Chromo PF00385.19 CDJ67604.1 - 4.9e-11 42.1 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDJ67604.1 - 7.3e-10 39.0 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ67604.1 - 0.036 13.6 0.0 0.09 12.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 CDJ67605.1 - 1.9e-13 50.2 0.0 3.4e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-A20 PF01754.11 CDJ67607.1 - 1e-11 44.1 6.4 1e-11 44.1 4.4 2.5 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.11 CDJ67607.1 - 1.9e-10 40.4 8.6 1.9e-10 40.4 6.0 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger DUF4428 PF14471.1 CDJ67607.1 - 0.28 10.9 4.1 3.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Herpes_BLLF1 PF05109.8 CDJ67607.1 - 8 4.2 28.0 10 3.9 19.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PRRSV_Env PF02340.10 CDJ67609.1 - 0.0047 16.1 0.0 0.023 13.8 0.0 2.0 2 0 0 2 2 2 1 PRRSV putative envelope protein Gene66 PF02053.10 CDJ67609.1 - 0.024 14.0 0.1 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Gene 66 (IR5) protein TFIID_30kDa PF03540.8 CDJ67611.1 - 7.7e-07 28.8 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit MYEOV2 PF15004.1 CDJ67611.1 - 0.16 12.5 0.0 0.57 10.7 0.0 1.8 2 0 0 2 2 2 0 Myeloma-overexpressed-like Prefoldin PF02996.12 CDJ67612.1 - 4.1e-18 65.1 2.5 5.1e-18 64.8 1.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Hrs_helical PF12210.3 CDJ67612.1 - 0.088 13.0 2.5 1 9.6 0.1 2.1 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TMF_TATA_bd PF12325.3 CDJ67612.1 - 0.28 10.9 3.9 0.37 10.5 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.1 CDJ67612.1 - 0.77 9.7 4.6 9.4 6.2 0.2 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF2325 PF10087.4 CDJ67613.1 - 0.094 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) AflR PF08493.5 CDJ67617.1 - 9.9 5.1 6.7 12 4.7 4.6 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Asp_protease_2 PF13650.1 CDJ67621.1 - 2.6e-09 37.4 0.0 6.4e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ67621.1 - 1e-07 31.6 0.0 2.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ67621.1 - 3.4e-07 30.2 0.0 6.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CDJ67621.1 - 3.6e-07 30.0 0.0 1.2e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ67621.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease IncA PF04156.9 CDJ67622.1 - 6.7e-05 22.5 7.4 6.7e-05 22.5 5.1 3.9 3 1 0 3 3 3 1 IncA protein Surface_antigen PF11054.3 CDJ67626.1 - 2e-20 73.2 19.3 6.3e-11 42.1 0.3 6.1 4 2 2 6 6 6 5 Sporozoite TA4 surface antigen SPT2 PF08243.6 CDJ67627.1 - 3.1e-07 30.7 9.5 3.1e-07 30.7 6.6 5.6 5 1 0 5 5 5 1 SPT2 chromatin protein PAT1 PF09770.4 CDJ67627.1 - 0.0017 16.6 66.7 0.0017 16.6 46.2 3.2 2 1 1 3 3 3 1 Topoisomerase II-associated protein PAT1 DNA_pol3_a_NII PF11490.3 CDJ67628.1 - 3.1 7.4 9.0 6.6 6.3 2.3 2.3 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Peptidase_C54 PF03416.14 CDJ67629.1 - 2.8e-11 43.0 0.0 7.2e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C54 SR-25 PF10500.4 CDJ67629.1 - 0.0071 15.8 1.2 0.0071 15.8 0.8 15.8 10 3 3 15 15 15 2 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ67630.1 - 0.0059 16.0 1.2 0.0059 16.0 0.8 12.2 7 2 2 11 11 11 2 Nuclear RNA-splicing-associated protein COPI_C PF06957.6 CDJ67631.1 - 0.0088 14.6 4.3 0.011 14.3 3.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Mus7 PF09462.5 CDJ67631.1 - 0.011 14.6 2.2 0.01 14.7 1.5 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family eIF3_subunit PF08597.5 CDJ67631.1 - 0.038 13.5 9.2 0.052 13.1 6.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Med15 PF09606.5 CDJ67631.1 - 0.093 10.9 18.7 0.1 10.7 13.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dicty_REP PF05086.7 CDJ67631.1 - 0.17 9.5 2.3 0.18 9.5 1.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.4 CDJ67631.1 - 0.23 9.6 8.4 0.27 9.4 5.8 1.0 1 0 0 1 1 1 0 Transmembrane protein NARP1 PF12569.3 CDJ67631.1 - 0.49 9.0 7.2 0.52 9.0 5.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Suf PF05843.9 CDJ67631.1 - 0.78 9.4 5.8 0.96 9.1 4.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1183 PF06682.7 CDJ67631.1 - 1.3 8.5 7.3 1.4 8.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Alpha_GJ PF03229.8 CDJ67631.1 - 1.5 9.2 20.7 2.9 8.2 2.1 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J FimP PF09766.4 CDJ67631.1 - 1.9 7.4 9.3 2.3 7.2 6.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF2681 PF10883.3 CDJ67631.1 - 2.1 8.6 11.1 3 8.1 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CRF1 PF10380.4 CDJ67633.1 - 4.6 7.6 6.0 1.8 8.9 1.3 2.2 2 0 0 2 2 2 0 Transcription factor CRF1 PAT1 PF09770.4 CDJ67633.1 - 6.7 4.8 44.3 0.78 7.9 20.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 YodA PF09223.6 CDJ67634.1 - 0.034 13.8 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 YodA lipocalin-like domain Retrotrans_gag PF03732.12 CDJ67634.1 - 0.056 13.5 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3552 PF12072.3 CDJ67635.1 - 0.01 15.0 0.2 0.02 14.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) MFS_2 PF13347.1 CDJ67636.1 - 4.2e-21 74.8 0.4 4.8e-21 74.6 0.3 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 CDJ67636.1 - 0.0016 17.1 0.4 0.0021 16.8 0.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FAM176 PF14851.1 CDJ67636.1 - 0.064 12.9 0.4 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 FAM176 family RRF PF01765.14 CDJ67637.1 - 2.9e-15 56.1 5.1 3.1e-15 56.0 3.5 1.0 1 0 0 1 1 1 1 Ribosome recycling factor SpoIIIAH PF12685.2 CDJ67637.1 - 0.0061 16.0 5.0 0.0071 15.8 3.5 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein Syntaxin PF00804.20 CDJ67637.1 - 0.023 14.8 3.3 0.027 14.6 2.3 1.2 1 0 0 1 1 1 0 Syntaxin DUF2103 PF09876.4 CDJ67637.1 - 0.15 11.7 0.5 0.26 11.0 0.4 1.4 1 1 0 1 1 1 0 Predicted metal-binding protein (DUF2103) DUF2265 PF10023.4 CDJ67637.1 - 0.2 10.7 4.4 0.22 10.6 3.0 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) GlutR_dimer PF00745.15 CDJ67637.1 - 0.44 10.5 4.3 0.58 10.1 3.0 1.3 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF883 PF05957.8 CDJ67637.1 - 3.3 8.1 7.5 18 5.8 5.0 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) SNARE PF05739.14 CDJ67638.1 - 0.00012 21.6 0.1 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 SNARE domain DUF4201 PF13870.1 CDJ67638.1 - 0.022 14.2 0.4 0.027 13.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2216 PF10226.4 CDJ67638.1 - 0.7 9.3 8.7 0.91 9.0 6.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) Sporozoite_P67 PF05642.6 CDJ67638.1 - 0.78 7.5 9.1 0.84 7.4 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_60s PF00428.14 CDJ67640.1 - 0.24 11.8 6.0 0.48 10.8 4.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med15 PF09606.5 CDJ67640.1 - 6.6 4.7 29.7 9.7 4.2 20.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PRMT5 PF05185.11 CDJ67642.1 - 1.3e-85 288.0 0.0 7.5e-55 186.6 0.0 3.5 2 2 0 2 2 2 2 PRMT5 arginine-N-methyltransferase DUF1645 PF07816.6 CDJ67642.1 - 0.00035 21.0 1.1 0.00035 21.0 0.7 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1645) SR-25 PF10500.4 CDJ67642.1 - 0.14 11.5 42.1 0.062 12.7 6.0 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3493 PF11998.3 CDJ67643.1 - 5 7.0 10.9 6.8 6.6 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) Shadoo PF14999.1 CDJ67644.1 - 0.088 12.6 8.4 0.099 12.4 5.8 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PepSY_2 PF13670.1 CDJ67644.1 - 0.38 10.6 4.7 0.44 10.4 3.2 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 CDJ67644.1 - 2.3 8.6 10.0 2.9 8.3 6.9 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Helicase_C_2 PF13307.1 CDJ67645.1 - 4.6e-10 39.6 0.0 5.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain DUF945 PF06097.6 CDJ67646.1 - 1.4 7.6 10.4 1.6 7.4 2.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF945) WSC PF01822.14 CDJ67646.1 - 3.6 7.5 36.9 2.4 8.1 4.8 3.2 1 1 2 3 3 3 0 WSC domain CTP_transf_3 PF02348.14 CDJ67646.1 - 4.5 6.8 10.8 3.9 7.0 6.9 1.4 1 1 0 1 1 1 0 Cytidylyltransferase Parvo_coat PF00740.13 CDJ67646.1 - 6.1 5.6 8.9 7.8 5.3 6.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Pro_isomerase PF00160.16 CDJ67647.1 - 5.7e-46 156.5 0.2 6.3e-46 156.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RPAP1_C PF08620.5 CDJ67648.1 - 6.8e-17 61.0 0.5 1e-14 54.0 0.2 2.9 2 0 0 2 2 2 2 RPAP1-like, C-terminal Ycf1 PF05758.7 CDJ67648.1 - 2.8 5.5 6.7 4.8 4.7 4.6 1.3 1 0 0 1 1 1 0 Ycf1 Med15 PF09606.5 CDJ67649.1 - 0.0023 16.2 17.6 0.0032 15.7 12.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDJ67649.1 - 0.43 9.5 3.1 0.51 9.2 2.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDJ67649.1 - 1.1 8.8 7.3 1.4 8.5 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PHD_3 PF13922.1 CDJ67649.1 - 1.2 9.4 7.7 2.4 8.4 3.1 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PAT1 PF09770.4 CDJ67649.1 - 4.8 5.2 15.6 5.3 5.1 10.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAP PF08373.5 CDJ67650.1 - 0.00061 19.5 0.0 0.0017 18.1 0.0 1.8 1 0 0 1 1 1 1 RAP domain BHD_3 PF10405.4 CDJ67651.1 - 2.4e-05 23.9 0.1 6.2e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CDJ67651.1 - 3.9e-05 23.0 5.2 0.0023 17.3 0.0 3.4 3 0 0 3 3 3 2 Rad4 transglutaminase-like domain HsdM_N PF12161.3 CDJ67651.1 - 0.15 12.4 0.2 0.52 10.7 0.1 1.9 1 0 0 1 1 1 0 HsdM N-terminal domain Pkinase PF00069.20 CDJ67652.1 - 4.4e-37 127.6 0.1 3.4e-36 124.7 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67652.1 - 1.3e-14 53.9 0.5 5.7e-14 51.8 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CDJ67652.1 - 0.0096 15.2 0.0 0.0096 15.2 0.0 2.4 3 0 0 3 3 3 1 RIO1 family Herpes_UL87 PF03043.9 CDJ67652.1 - 0.1 10.9 0.0 0.1 10.9 0.0 3.8 2 2 0 2 2 2 0 Herpesvirus UL87 family Pox_ser-thr_kin PF05445.6 CDJ67652.1 - 0.92 8.2 0.0 1.4 7.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ETRAMP PF09716.5 CDJ67652.1 - 2.5 8.0 4.2 7.8 6.5 0.0 3.7 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ATP-synt_D PF01813.12 CDJ67653.1 - 1e-57 194.8 2.3 1.3e-57 194.5 1.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit D CorA PF01544.13 CDJ67653.1 - 0.036 13.1 0.2 0.055 12.5 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PAE PF03283.8 CDJ67653.1 - 0.065 11.8 0.0 2 6.9 0.0 2.1 2 0 0 2 2 2 0 Pectinacetylesterase Spore_SspJ PF09575.5 CDJ67653.1 - 1.2 9.4 7.1 0.55 10.4 1.0 2.8 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) PAT1 PF09770.4 CDJ67654.1 - 0.34 9.0 6.1 0.38 8.9 4.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DEAD PF00270.24 CDJ67655.1 - 7.6e-42 142.6 0.9 1.8e-41 141.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ67655.1 - 5.2e-21 74.3 0.0 2.3e-20 72.2 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 CDJ67656.1 - 1.7e-37 128.9 0.2 6.5e-24 84.4 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67656.1 - 5.3e-23 81.4 0.0 1.9e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CDJ67656.1 - 0.00029 19.9 0.5 0.00098 18.2 0.4 1.9 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CDJ67656.1 - 0.00044 19.2 0.6 0.0014 17.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like LSM PF01423.17 CDJ67658.1 - 3.2e-19 68.2 0.1 3.8e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DEAD PF00270.24 CDJ67660.1 - 5e-34 117.2 0.0 8.8e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ67660.1 - 3.3e-22 78.1 0.0 9.9e-22 76.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDJ67660.1 - 3.3e-06 27.0 0.0 1.8e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CDJ67660.1 - 0.0004 19.2 0.0 0.00091 18.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CDJ67660.1 - 0.007 16.5 0.0 0.62 10.2 0.0 3.8 2 2 0 2 2 2 1 AAA domain BAF1_ABF1 PF04684.8 CDJ67660.1 - 7.7 5.2 10.8 0.12 11.1 1.8 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor AP2 PF00847.15 CDJ67661.1 - 9.2e-08 32.1 0.2 3.2e-07 30.3 0.1 2.1 2 0 0 2 2 2 1 AP2 domain Herpes_UL87 PF03043.9 CDJ67662.1 - 7.7 4.7 8.0 0.25 9.6 0.4 2.2 2 1 0 2 2 2 0 Herpesvirus UL87 family HECT PF00632.20 CDJ67664.1 - 8.8e-92 307.6 0.0 1.7e-91 306.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_60s PF00428.14 CDJ67664.1 - 0.0024 18.2 6.4 0.0024 18.2 4.5 8.0 8 1 1 9 9 9 2 60s Acidic ribosomal protein LIM PF00412.17 CDJ67665.1 - 3.2 7.9 8.7 6.7 6.8 6.1 1.6 1 0 0 1 1 1 0 LIM domain DnaJ PF00226.26 CDJ67666.1 - 2e-25 88.2 0.2 2e-25 88.2 0.1 2.4 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 CDJ67666.1 - 3.8e-09 36.4 2.5 1.3e-05 25.1 0.8 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CDJ67666.1 - 1.1e-08 35.0 1.8 0.0047 17.0 0.2 3.6 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CDJ67666.1 - 1.2e-08 34.8 1.9 3.3e-05 23.9 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CDJ67666.1 - 1e-07 31.8 1.9 0.017 15.4 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CDJ67666.1 - 2.8e-06 27.0 0.3 0.017 14.9 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CDJ67666.1 - 3.1e-05 23.9 3.0 0.094 13.0 0.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger Kinesin PF00225.18 CDJ67667.1 - 2.1e-69 233.7 0.0 8.1e-69 231.8 0.0 1.8 1 1 0 1 1 1 1 Kinesin motor domain Solute_trans_a PF03619.11 CDJ67668.1 - 4.1e-29 101.7 5.8 1.6e-12 47.3 0.3 3.1 3 0 0 3 3 3 3 Organic solute transporter Ostalpha TPR_11 PF13414.1 CDJ67671.1 - 1.1e-15 57.0 3.1 3.3e-08 33.0 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CDJ67671.1 - 6.9e-11 41.2 2.2 0.022 14.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ67671.1 - 1.1e-09 37.4 5.8 0.015 15.1 0.2 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ67671.1 - 5.3e-07 29.3 1.0 0.00012 21.8 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ67671.1 - 5.7e-07 30.0 7.7 0.0005 20.6 0.5 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ67671.1 - 7.8e-06 26.1 8.6 0.0013 19.0 2.1 3.0 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ67671.1 - 8.3e-06 25.9 9.0 0.031 14.9 0.3 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ67671.1 - 1.1e-05 25.3 1.8 0.022 14.7 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CDJ67671.1 - 0.00011 22.2 0.9 0.00032 20.7 0.4 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CDJ67671.1 - 0.00017 21.3 2.8 0.096 12.5 0.2 3.3 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 CDJ67671.1 - 0.0021 18.1 2.4 0.036 14.2 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ67671.1 - 0.0031 17.1 4.3 0.52 10.2 0.0 3.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CDJ67671.1 - 0.0033 17.4 2.8 0.0033 17.4 2.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ67671.1 - 0.0066 16.8 10.0 4.4 7.9 0.0 4.6 4 1 0 4 4 3 1 Tetratricopeptide repeat T4SS PF07996.6 CDJ67671.1 - 0.011 15.5 5.4 0.43 10.4 3.4 2.3 1 1 0 1 1 1 0 Type IV secretion system proteins TPR_8 PF13181.1 CDJ67671.1 - 0.011 15.3 2.3 2.6 8.0 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA_13 PF13166.1 CDJ67671.1 - 0.014 13.8 3.2 0.016 13.7 2.2 1.2 1 0 0 1 1 1 0 AAA domain Paf67 PF10255.4 CDJ67671.1 - 0.031 13.1 0.1 0.04 12.7 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 CCDC71L PF15374.1 CDJ67671.1 - 0.083 12.1 6.3 0.12 11.6 4.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Flagellin_N PF00669.15 CDJ67671.1 - 0.57 9.9 4.0 17 5.2 2.8 2.2 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region MIT PF04212.13 CDJ67671.1 - 1.3 8.9 9.7 0.27 11.1 0.7 3.5 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain SPOR PF05036.8 CDJ67671.1 - 4 7.6 6.1 1.7 8.8 1.5 2.3 1 1 1 2 2 2 0 Sporulation related domain EF-hand_6 PF13405.1 CDJ67672.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain ubiquitin PF00240.18 CDJ67672.1 - 0.0098 15.2 0.0 4.9 6.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin family EF-hand_1 PF00036.27 CDJ67672.1 - 0.022 14.0 0.0 0.053 12.8 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 CDJ67672.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair ACOX PF01756.14 CDJ67673.1 - 6.9e-34 116.8 0.7 1.1e-33 116.1 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CDJ67673.1 - 3.6e-16 59.5 0.1 7.8e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CDJ67673.1 - 2.9e-12 45.8 0.0 7.3e-12 44.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CDJ67673.1 - 0.12 12.4 6.0 0.43 10.6 0.8 3.4 3 1 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1440 PF07274.7 CDJ67673.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) PP2C PF00481.16 CDJ67674.1 - 3.7e-38 131.3 0.0 4.4e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CDJ67674.1 - 5.3e-07 29.2 0.0 2.4e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CDJ67674.1 - 4.1e-06 26.6 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Lactamase_B_2 PF12706.2 CDJ67676.1 - 9.8e-09 35.0 0.0 0.00024 20.7 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CDJ67676.1 - 4.6e-06 26.4 0.0 0.0031 17.2 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Ribosomal_L37e PF01907.14 CDJ67677.1 - 3.9e-26 90.6 12.9 3.9e-26 90.6 9.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e SelR PF01641.13 CDJ67677.1 - 0.0011 18.6 0.3 0.0017 18.0 0.2 1.3 1 1 0 1 1 1 1 SelR domain DZR PF12773.2 CDJ67677.1 - 0.011 15.4 1.2 0.018 14.8 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 CDJ67677.1 - 0.028 13.6 1.1 0.053 12.7 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF1462 PF07315.6 CDJ67677.1 - 0.036 14.0 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) zf-C2HC5 PF06221.8 CDJ67677.1 - 0.052 13.3 0.6 0.088 12.5 0.4 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type FdhE PF04216.7 CDJ67677.1 - 0.069 12.8 1.8 0.084 12.5 1.3 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zinc_ribbon_2 PF13240.1 CDJ67677.1 - 3.4 7.2 5.5 7.1 6.2 2.5 2.1 1 1 1 2 2 2 0 zinc-ribbon domain SR-25 PF10500.4 CDJ67679.1 - 0.0099 15.3 43.3 0.048 13.1 8.2 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.2 CDJ67680.1 - 7.4 6.1 14.9 0.77 9.3 1.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Elf1 PF05129.8 CDJ67681.1 - 4.1e-21 74.4 0.3 8.2e-21 73.4 0.2 1.5 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like SR-25 PF10500.4 CDJ67681.1 - 0.0072 15.8 24.8 0.01 15.3 17.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Zn-ribbon_8 PF09723.5 CDJ67681.1 - 0.18 11.8 2.0 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF1777 PF08648.7 CDJ67681.1 - 0.76 9.4 13.4 1 9.0 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Atrophin-1 PF03154.10 CDJ67681.1 - 0.83 7.7 19.0 1 7.3 13.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family CDC27 PF09507.5 CDJ67681.1 - 1.8 7.7 26.2 2.3 7.3 18.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PIH1 PF08190.7 CDJ67681.1 - 2.8 7.2 6.7 3.7 6.8 4.6 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF812 PF05667.6 CDJ67681.1 - 4.4 5.6 15.1 5.4 5.3 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TP53IP5 PF15331.1 CDJ67681.1 - 8.5 6.2 14.0 9.3 6.0 9.2 1.4 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF4551 PF15087.1 CDJ67681.1 - 9.9 4.3 12.2 12 4.1 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HIT PF01230.18 CDJ67682.1 - 3.6e-11 43.4 0.0 8.3e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 HIT domain DUF4129 PF13559.1 CDJ67682.1 - 0.4 10.6 2.8 2.4 8.1 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4129) SR-25 PF10500.4 CDJ67683.1 - 0.0058 16.1 12.5 0.0058 16.1 8.6 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 CDJ67683.1 - 0.89 9.2 10.0 2.6 7.7 6.9 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.3 CDJ67683.1 - 3.1 7.0 10.1 5.3 6.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TOM13 PF08219.6 CDJ67684.1 - 0.32 10.7 0.0 0.32 10.7 0.0 6.6 8 2 1 9 9 9 0 Outer membrane protein TOM13 NTP_transferase PF00483.18 CDJ67685.1 - 3.9e-13 49.2 0.0 4.4e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CDJ67685.1 - 2.5e-08 34.1 0.0 2.7e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4591 PF15261.1 CDJ67686.1 - 0.058 13.6 15.0 0.071 13.3 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) DUF4638 PF15472.1 CDJ67686.1 - 0.21 11.1 6.5 0.25 10.9 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) MDFI PF15316.1 CDJ67686.1 - 0.31 11.0 9.1 0.36 10.8 6.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor UMP1 PF05348.6 CDJ67686.1 - 1.1 9.2 11.2 3.6 7.5 1.0 2.1 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 Med15 PF09606.5 CDJ67686.1 - 1.7 6.7 42.0 1.8 6.6 29.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.1 CDJ67686.1 - 2.3 7.8 7.0 2.8 7.6 4.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Trp_oprn_chp PF09534.5 CDJ67686.1 - 2.9 7.4 17.2 3.3 7.2 11.9 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Med19 PF10278.4 CDJ67686.1 - 3.4 7.3 7.7 1.4 8.5 0.6 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Neur_chan_memb PF02932.11 CDJ67686.1 - 4.3 7.1 8.4 5.1 6.9 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.7 CDJ67686.1 - 4.5 6.3 10.6 5.7 6.0 7.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger LAMTOR PF15454.1 CDJ67686.1 - 5.3 7.3 17.0 0.28 11.5 4.2 2.2 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator PAT1 PF09770.4 CDJ67686.1 - 6.3 4.9 36.6 7.3 4.6 25.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hexapep PF00132.19 CDJ67687.1 - 2.6e-10 39.3 1.1 1.4e-07 30.6 0.1 3.6 1 1 3 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CDJ67687.1 - 0.014 14.9 1.0 0.047 13.2 0.1 2.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Prenyltransf PF01255.14 CDJ67689.1 - 1.2e-45 155.3 0.0 6.8e-45 152.9 0.0 1.8 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase FPN1 PF06963.7 CDJ67689.1 - 0.5 8.6 2.2 0.33 9.2 0.4 1.5 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Med15 PF09606.5 CDJ67689.1 - 1.8 6.6 25.4 0.0096 14.1 8.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDJ67690.1 - 0.0068 16.4 11.8 0.0068 16.4 8.2 4.9 3 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SOBP PF15279.1 CDJ67690.1 - 0.0097 16.3 32.8 0.24 11.7 16.2 2.2 2 0 0 2 2 2 2 Sine oculis-binding protein Med15 PF09606.5 CDJ67690.1 - 1.1 7.4 88.2 0.59 8.2 36.2 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDJ67690.1 - 1.9 7.8 44.3 1.5 8.1 21.6 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal rve PF00665.21 CDJ67691.1 - 1.3e-20 73.7 0.0 2.1e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDJ67691.1 - 4.1e-12 45.5 0.0 8.9e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PALP PF00291.20 CDJ67694.1 - 9.5e-52 176.1 0.0 1.3e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HECT PF00632.20 CDJ67695.1 - 5.5e-81 272.1 0.0 8e-81 271.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Auxin_resp PF06507.8 CDJ67696.1 - 9.6e-05 22.1 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 Auxin response factor WHIM2 PF15613.1 CDJ67696.1 - 0.018 14.9 0.2 0.19 11.7 0.0 3.0 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 Sec63 PF02889.11 CDJ67697.1 - 6.1e-09 35.5 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DUF4602 PF15375.1 CDJ67697.1 - 0.0027 17.7 4.1 0.0027 17.7 2.8 2.5 2 1 0 2 2 1 1 Domain of unknown function (DUF4602) DUF2722 PF10846.3 CDJ67697.1 - 0.03 13.3 0.4 0.03 13.3 0.2 2.7 2 1 0 2 2 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.8 CDJ67697.1 - 0.06 13.2 15.8 0.28 11.0 3.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.4 CDJ67697.1 - 0.21 11.8 5.2 2.6 8.2 0.3 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like SpoVR PF04293.8 CDJ67697.1 - 0.53 8.5 4.9 4.9 5.4 0.5 2.2 2 0 0 2 2 2 0 SpoVR like protein Rsm1 PF08600.5 CDJ67697.1 - 1.6 8.6 5.2 1 9.2 0.3 2.5 2 0 0 2 2 2 0 Rsm1-like DUF2195 PF09961.4 CDJ67697.1 - 3.7 7.3 6.6 0.18 11.6 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) LytR_cpsA_psr PF03816.9 CDJ67697.1 - 5.5 6.8 8.6 6.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Cell envelope-related transcriptional attenuator domain dsDNA_bind PF01984.15 CDJ67697.1 - 7.5 6.6 42.8 0.095 12.7 1.3 3.2 3 0 0 3 3 3 0 Double-stranded DNA-binding domain DUF3306 PF11748.3 CDJ67697.1 - 8.2 7.1 9.8 13 6.4 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF3464 PF11947.3 CDJ67697.1 - 9.4 5.6 6.7 15 5.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) RLI PF04068.10 CDJ67699.1 - 9.3e-07 28.3 0.1 2e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Macoilin PF09726.4 CDJ67699.1 - 0.24 9.6 7.6 0.29 9.3 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1517 PF07466.6 CDJ67699.1 - 0.47 9.3 4.5 0.065 12.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) COOH-NH2_lig PF14395.1 CDJ67701.1 - 0.14 11.2 1.9 0.24 10.4 1.0 1.5 1 1 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 BLOC1_2 PF10046.4 CDJ67701.1 - 1.9 8.7 9.3 1.4 9.0 0.4 3.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EAP30 PF04157.11 CDJ67701.1 - 3.4 6.7 9.6 0.051 12.7 0.6 2.3 3 0 0 3 3 3 0 EAP30/Vps36 family SET PF00856.23 CDJ67702.1 - 6.3e-08 33.0 0.2 2.8e-07 31.0 0.0 2.1 2 1 0 2 2 2 1 SET domain CTNNBL PF08216.6 CDJ67702.1 - 0.081 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear TBCC PF07986.7 CDJ67704.1 - 0.009 15.4 0.1 0.029 13.7 0.1 1.8 1 1 0 1 1 1 1 Tubulin binding cofactor C SMC_N PF02463.14 CDJ67705.1 - 5e-51 173.0 0.0 9.2e-51 172.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CDJ67705.1 - 8.4e-15 54.7 0.2 1.7e-13 50.6 0.0 3.3 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CDJ67705.1 - 1.1e-12 48.5 0.3 1.3e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CDJ67705.1 - 0.00026 20.4 0.0 0.00059 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CDJ67705.1 - 0.00072 19.9 42.7 0.00072 19.9 29.6 6.9 2 2 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CDJ67705.1 - 0.00087 19.5 0.4 0.0026 18.0 0.2 6.4 4 2 2 6 6 6 2 ABC transporter Reo_sigmaC PF04582.7 CDJ67705.1 - 0.12 11.5 29.3 1.4 8.0 0.5 5.2 3 2 2 5 5 5 0 Reovirus sigma C capsid protein AAA_15 PF13175.1 CDJ67705.1 - 3.9 6.4 16.0 0.047 12.7 4.9 2.5 2 1 0 2 2 2 0 AAA ATPase domain Med15 PF09606.5 CDJ67706.1 - 0.38 8.8 43.0 0.38 8.9 29.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ67706.1 - 1.9 6.5 29.1 2 6.5 20.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ67706.1 - 2.9 7.6 22.8 3.1 7.6 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 CDJ67706.1 - 3 5.4 8.6 2.8 5.5 6.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 CDJ67706.1 - 3.4 7.4 7.6 4.5 6.9 5.3 1.3 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 CDJ67706.1 - 3.4 7.4 9.7 3.8 7.3 6.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1675 PF07897.6 CDJ67706.1 - 3.9 7.2 15.8 4.8 6.9 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4569 PF15133.1 CDJ67706.1 - 4.4 6.6 13.9 5 6.4 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DNA_pol_viral_N PF00242.12 CDJ67706.1 - 4.5 6.2 14.6 4.9 6.0 10.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Metallophos PF00149.23 CDJ67707.1 - 2.5e-30 105.3 0.0 1.8e-26 92.7 0.0 2.0 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Peptidase_C50 PF03568.12 CDJ67710.1 - 1.3e-06 27.3 0.0 1e-05 24.4 0.0 7.0 9 0 0 9 9 9 3 Peptidase family C50 DUF4179 PF13786.1 CDJ67710.1 - 2.1 8.6 2.3 77 3.6 0.0 5.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) ADK PF00406.17 CDJ67711.1 - 6.1e-29 100.8 0.0 6.1e-22 78.1 0.0 2.6 2 0 0 2 2 2 2 Adenylate kinase Rad9 PF04139.8 CDJ67711.1 - 7.6e-07 28.4 0.1 0.034 13.2 0.0 2.4 2 0 0 2 2 2 2 Rad9 AAA_18 PF13238.1 CDJ67711.1 - 0.00073 19.8 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CDJ67711.1 - 0.00085 20.1 0.0 0.0017 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain SR-25 PF10500.4 CDJ67712.1 - 0.0037 16.7 20.7 0.0047 16.4 14.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Plasmodium_Vir PF05795.6 CDJ67712.1 - 0.22 10.7 3.8 0.23 10.6 2.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF572 PF04502.8 CDJ67712.1 - 0.57 9.3 18.0 0.63 9.2 12.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF966 PF06136.8 CDJ67712.1 - 1.1 8.6 17.9 1.3 8.4 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) YadA_anchor PF03895.10 CDJ67712.1 - 1.1 9.2 4.8 1.9 8.5 0.4 2.4 2 0 0 2 2 2 0 YadA-like C-terminal region DUF2215 PF10225.4 CDJ67712.1 - 4.7 6.5 6.1 5.8 6.2 4.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) SprA-related PF12118.3 CDJ67714.1 - 0.0029 17.0 16.6 0.0029 17.0 11.5 2.1 2 0 0 2 2 2 2 SprA-related family Dehydrin PF00257.14 CDJ67714.1 - 0.19 12.0 0.0 0.19 12.0 0.0 4.2 4 0 0 4 4 4 0 Dehydrin RAB3GAP2_N PF14655.1 CDJ67714.1 - 0.7 8.8 11.3 0.012 14.5 2.7 1.7 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Eapp_C PF10238.4 CDJ67715.1 - 1.3e-10 41.2 0.7 1.3e-10 41.2 0.5 1.9 2 0 0 2 2 2 1 E2F-associated phosphoprotein TFIIA PF03153.8 CDJ67715.1 - 0.061 13.2 5.7 0.069 13.0 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3633 PF12315.3 CDJ67715.1 - 1.1 8.5 11.5 0.18 11.1 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) DUF3498 PF12004.3 CDJ67715.1 - 5.4 6.0 23.7 6.5 5.7 16.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Secretin_N_2 PF07655.8 CDJ67715.1 - 5.8 7.3 31.4 1.8 8.9 3.3 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DUF605 PF04652.11 CDJ67715.1 - 7.3 5.8 17.2 8.9 5.5 11.9 1.2 1 0 0 1 1 1 0 Vta1 like Shadoo PF14999.1 CDJ67716.1 - 0.019 14.8 5.2 0.019 14.8 3.6 4.0 2 1 2 4 4 4 0 Shadow of prion protein, neuroprotective DUF4367 PF14285.1 CDJ67716.1 - 0.44 9.8 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) AAA_23 PF13476.1 CDJ67716.1 - 0.77 10.0 14.0 1.1 9.5 9.7 1.3 1 0 0 1 1 1 0 AAA domain PLRV_ORF5 PF01690.12 CDJ67716.1 - 1.6 7.7 22.3 2.2 7.3 15.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ycf1 PF05758.7 CDJ67716.1 - 2.4 5.7 13.7 2.6 5.6 9.5 1.1 1 0 0 1 1 1 0 Ycf1 V_ATPase_I PF01496.14 CDJ67716.1 - 6.1 4.5 6.4 7.3 4.3 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.2 CDJ67716.1 - 8.3 3.9 15.3 9.3 3.7 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SRP-alpha_N PF04086.8 CDJ67716.1 - 9.4 5.5 31.3 15 4.8 21.4 1.5 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_S6e PF01092.14 CDJ67717.1 - 8.2e-54 180.6 0.1 1.1e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6e Med15 PF09606.5 CDJ67718.1 - 0.01 14.0 23.4 0.012 13.8 16.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ67718.1 - 0.018 14.3 1.2 0.021 14.1 0.8 1.1 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.1 CDJ67718.1 - 0.057 12.4 2.4 0.071 12.0 1.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PAT1 PF09770.4 CDJ67718.1 - 0.072 11.3 9.0 0.066 11.4 6.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2946 PF11162.3 CDJ67718.1 - 0.1 12.8 17.2 0.2 11.8 11.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Suf PF05843.9 CDJ67718.1 - 0.11 12.1 2.1 0.13 12.0 1.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ67718.1 - 0.16 11.0 6.2 0.19 10.7 4.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4175 PF13779.1 CDJ67718.1 - 0.2 9.3 13.1 0.25 9.0 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DivIC PF04977.10 CDJ67718.1 - 1.6 8.2 7.3 2.7 7.5 5.0 1.3 1 0 0 1 1 1 0 Septum formation initiator FCP1_C PF09309.5 CDJ67718.1 - 1.7 7.8 5.7 2.7 7.2 4.0 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Herpes_DNAp_acc PF04929.7 CDJ67719.1 - 1.2 8.0 5.9 2.9 6.7 4.1 1.6 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ycf1 PF05758.7 CDJ67719.1 - 2 6.0 5.3 2.7 5.5 3.7 1.1 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 CDJ67719.1 - 3.2 6.4 9.6 5.4 5.7 6.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Baculo_PP31 PF05311.6 CDJ67719.1 - 3.4 6.8 7.6 6.1 6.0 5.3 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Hid1 PF12722.2 CDJ67719.1 - 5.1 4.6 9.4 8.1 3.9 6.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 CDJ67720.1 - 0.075 11.3 2.2 0.13 10.4 1.5 1.6 1 0 0 1 1 1 0 Membrane transport protein HEAT PF02985.17 CDJ67720.1 - 0.087 12.9 2.0 6.1 7.1 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Cellulose_synt PF03552.9 CDJ67720.1 - 2.4 6.3 10.8 4 5.6 7.5 1.3 1 0 0 1 1 1 0 Cellulose synthase Asp-B-Hydro_N PF05279.6 CDJ67720.1 - 6.6 6.5 31.6 23 4.7 21.9 1.9 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sororin PF09666.5 CDJ67722.1 - 0.0069 16.5 6.3 0.0084 16.3 4.3 1.2 1 0 0 1 1 1 1 Sororin protein TIP41 PF04176.8 CDJ67722.1 - 0.16 11.2 0.3 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 TIP41-like family TFIIA PF03153.8 CDJ67722.1 - 0.42 10.4 14.7 0.49 10.2 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ67722.1 - 0.98 7.5 25.2 1.1 7.3 17.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ67722.1 - 1.1 9.5 4.5 1.4 9.2 3.1 1.2 1 0 0 1 1 1 0 AAA domain APC_CDC26 PF10471.4 CDJ67722.1 - 1.4 9.7 21.2 4.8 7.9 2.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PHD_3 PF13922.1 CDJ67722.1 - 8.5 6.7 16.4 6.5 7.0 1.2 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Med15 PF09606.5 CDJ67722.1 - 9.2 4.3 30.7 12 3.9 21.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Surface_antigen PF11054.3 CDJ67723.1 - 2.4e-87 292.5 4.6 2.9e-87 292.2 3.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF2782 PF11191.3 CDJ67724.1 - 0.067 13.1 1.4 0.086 12.8 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) DUF3138 PF11336.3 CDJ67724.1 - 0.27 9.3 11.2 0.29 9.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF844 PF05815.6 CDJ67724.1 - 0.65 8.7 2.9 0.73 8.6 2.0 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) WD40 PF00400.27 CDJ67726.1 - 1.9e-11 43.4 27.7 1.6e-07 30.9 0.9 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Med15 PF09606.5 CDJ67726.1 - 0.048 11.8 46.7 0.14 10.3 6.5 3.1 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cytochrom_D1 PF02239.11 CDJ67726.1 - 0.23 9.7 0.0 0.44 8.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Syntaxin PF00804.20 CDJ67728.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Syntaxin DUF1204 PF06721.6 CDJ67728.1 - 0.029 13.6 1.5 0.041 13.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) TAF PF02969.12 CDJ67728.1 - 0.073 13.0 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Myco_arth_vir_N PF09610.5 CDJ67728.1 - 0.13 12.2 0.3 23 5.0 0.0 2.6 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Sigma54_AID PF00309.15 CDJ67728.1 - 0.25 10.8 10.2 0.47 9.9 7.0 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) PT PF04886.7 CDJ67730.1 - 4.7e-06 25.8 9.7 1.5e-05 24.1 6.7 1.9 1 0 0 1 1 1 1 PT repeat DUF3474 PF11960.3 CDJ67730.1 - 5.1 7.1 7.5 1.7 8.6 3.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) CD52 PF15116.1 CDJ67730.1 - 6.5 6.6 8.4 9.7 6.0 0.7 2.9 2 0 0 2 2 2 0 CAMPATH-1 antigen DUF4652 PF15525.1 CDJ67730.1 - 8.7 5.7 7.8 4.1 6.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4652) His_Phos_1 PF00300.17 CDJ67731.1 - 3.6e-12 46.6 0.0 4.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_60s PF00428.14 CDJ67731.1 - 0.0011 19.2 9.5 0.0018 18.6 6.6 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3583 PF12126.3 CDJ67731.1 - 0.012 14.7 0.0 0.012 14.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) Chal_sti_synt_N PF00195.14 CDJ67731.1 - 0.034 13.3 0.4 0.044 13.0 0.3 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF3123 PF11321.3 CDJ67731.1 - 0.052 13.8 2.4 0.068 13.4 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF506 PF04720.7 CDJ67732.1 - 0.81 9.2 15.2 0.1 12.2 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF506) N6_N4_Mtase PF01555.13 CDJ67732.1 - 2.4 7.5 6.5 17 4.7 4.5 2.1 1 1 0 1 1 1 0 DNA methylase Rod-binding PF10135.4 CDJ67733.1 - 0.0069 16.3 0.1 0.016 15.2 0.1 1.7 1 1 1 2 2 2 1 Rod binding protein DOT1 PF08123.8 CDJ67734.1 - 0.00019 20.8 0.0 0.00046 19.5 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.8 CDJ67734.1 - 0.0017 17.5 2.0 0.0033 16.5 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CDJ67734.1 - 0.26 11.3 0.0 0.26 11.3 0.0 3.3 2 1 0 2 2 2 0 Methyltransferase domain Guanylate_cyc PF00211.15 CDJ67735.1 - 1.3e-69 233.2 0.4 1.3e-34 119.2 1.9 3.4 2 2 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.15 CDJ67735.1 - 7e-06 25.2 0.0 2.5e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDJ67735.1 - 0.00051 20.5 0.1 0.046 14.1 0.0 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ARID PF01388.16 CDJ67737.1 - 8e-11 41.6 0.0 8e-11 41.6 0.0 2.6 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Transket_pyr PF02779.19 CDJ67738.1 - 2.8e-58 196.3 0.1 9.4e-58 194.6 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CDJ67738.1 - 1.2e-50 171.9 0.7 2.1e-50 171.1 0.0 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component LRR_6 PF13516.1 CDJ67739.1 - 2e-06 27.2 0.6 0.37 11.0 0.1 3.6 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.2 CDJ67739.1 - 0.00014 21.4 2.7 0.1 12.2 0.1 2.7 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDJ67739.1 - 0.0062 16.4 0.8 12 6.4 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich Repeat Spc7 PF08317.6 CDJ67740.1 - 3.3 6.2 9.2 0.15 10.6 0.2 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein HxlR PF01638.12 CDJ67741.1 - 0.036 13.6 0.9 0.082 12.5 0.1 2.0 2 0 0 2 2 2 0 HxlR-like helix-turn-helix Ery_res_leader1 PF08051.6 CDJ67741.1 - 9 6.1 7.7 0.76 9.5 0.7 2.3 2 0 0 2 2 2 0 Erythromycin resistance leader peptide UIM PF02809.15 CDJ67742.1 - 0.59 9.8 5.6 0.25 10.9 0.9 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif RunxI PF08504.6 CDJ67742.1 - 1.1 9.7 8.6 0.071 13.5 2.0 2.0 3 0 0 3 3 3 0 Runx inhibition domain LMF1 PF06762.9 CDJ67745.1 - 2e-47 161.8 9.2 5.9e-47 160.2 6.4 1.7 1 1 0 1 1 1 1 Lipase maturation factor XPG_I PF00867.13 CDJ67746.1 - 4.6e-24 84.2 0.1 1.5e-23 82.6 0.1 2.0 1 0 0 1 1 1 1 XPG I-region TSP_1 PF00090.14 CDJ67747.1 - 8.2e-103 336.3 221.6 1.1e-11 44.6 2.8 20.8 18 1 0 18 18 18 15 Thrombospondin type 1 domain Notch PF00066.12 CDJ67747.1 - 1.5e-25 89.1 110.2 2e-09 37.5 9.4 9.1 8 0 0 8 8 8 4 LNR domain DUF4381 PF14316.1 CDJ67747.1 - 0.026 14.6 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4328 PF14219.1 CDJ67747.1 - 0.19 11.0 0.2 0.39 9.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PgaD PF13994.1 CDJ67747.1 - 3.1 7.2 0.2 6.5 6.2 0.2 1.4 1 0 0 1 1 1 0 PgaD-like protein TMEM18 PF14770.1 CDJ67747.1 - 9.1 5.8 0.0 17 4.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 18 Rgp1 PF08737.5 CDJ67747.1 - 9.9 5.1 0.2 19 4.1 0.1 1.4 2 0 0 2 2 2 0 Rgp1 DUF663 PF04950.7 CDJ67748.1 - 4.3e-68 229.4 0.0 1.5e-58 198.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF663) AARP2CN PF08142.7 CDJ67748.1 - 4e-07 29.4 0.0 1.1e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CCDC66 PF15236.1 CDJ67749.1 - 0.00026 20.6 15.8 0.00026 20.6 10.9 3.0 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 66 SieB PF14163.1 CDJ67749.1 - 3.8 7.0 7.1 3.9 7.0 0.1 3.2 4 0 0 4 4 4 0 Superinfection exclusion protein B DUF2877 PF11392.3 CDJ67750.1 - 0.0026 17.9 0.2 0.004 17.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2877) CLAG PF03805.8 CDJ67751.1 - 0.92 6.7 0.0 2 5.6 0.0 1.4 2 0 0 2 2 2 0 Cytoadherence-linked asexual protein GST_C_3 PF14497.1 CDJ67752.1 - 9e-06 26.0 0.1 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 CDJ67752.1 - 5.2e-05 23.1 0.9 0.069 13.0 0.1 2.6 3 0 0 3 3 3 2 Tom37 C-terminal domain GST_C_2 PF13410.1 CDJ67752.1 - 0.0014 18.4 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain mit_SMPDase PF14724.1 CDJ67752.1 - 0.13 10.0 0.1 3.5 5.3 0.0 2.0 1 1 1 2 2 2 0 Mitochondrial-associated sphingomyelin phosphodiesterase EGF_CA PF07645.10 CDJ67753.1 - 3e-16 59.1 22.4 1.2e-08 34.7 4.7 4.1 3 0 0 3 3 3 3 Calcium-binding EGF domain cEGF PF12662.2 CDJ67753.1 - 2.7e-09 36.4 30.8 3.4e-07 29.7 4.5 4.2 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF_3 PF12947.2 CDJ67753.1 - 3.5e-09 36.4 25.5 0.0011 18.9 5.3 4.1 3 0 0 3 3 3 3 EGF domain Peptidase_C11 PF03415.9 CDJ67753.1 - 7.7e-08 31.7 0.0 4.1e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 Clostripain family Notch PF00066.12 CDJ67753.1 - 1.6e-07 31.4 1.3 1.6e-07 31.4 0.9 2.5 2 0 0 2 2 2 1 LNR domain EGF PF00008.22 CDJ67753.1 - 0.00047 20.0 23.5 0.016 15.1 3.9 4.9 4 1 1 5 5 5 2 EGF-like domain FXa_inhibition PF14670.1 CDJ67753.1 - 0.0042 17.1 7.8 0.0042 17.1 5.4 4.1 5 0 0 5 5 5 2 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CDJ67753.1 - 0.0045 16.9 6.0 0.13 12.4 0.7 3.3 2 0 0 2 2 2 1 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 CDJ67753.1 - 0.085 12.6 10.1 1.2 8.9 1.1 3.3 3 0 0 3 3 3 0 MSP1 EGF domain 1 Herpes_gE PF02480.11 CDJ67754.1 - 0.0036 15.6 0.1 0.0052 15.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2890 PF11081.3 CDJ67754.1 - 0.017 15.2 13.6 0.035 14.1 9.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) IncA PF04156.9 CDJ67754.1 - 0.04 13.5 1.6 0.22 11.0 0.0 2.5 3 0 0 3 3 3 0 IncA protein Nop14 PF04147.7 CDJ67754.1 - 0.067 11.1 5.8 0.092 10.6 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family CBM_20 PF00686.14 CDJ67755.1 - 5.6e-14 51.5 0.0 1.6e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain Med15 PF09606.5 CDJ67755.1 - 0.9 7.6 73.1 0.015 13.5 3.2 5.2 5 0 0 5 5 5 0 ARC105 or Med15 subunit of Mediator complex non-fungal Exonuc_VII_L PF02601.10 CDJ67756.1 - 0.0058 15.8 1.3 0.0058 15.8 0.9 7.5 5 2 0 5 5 5 2 Exonuclease VII, large subunit Mito_fiss_reg PF05308.6 CDJ67757.1 - 0.13 11.6 12.1 0.14 11.4 8.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AATF-Che1 PF13339.1 CDJ67757.1 - 0.27 11.4 2.8 0.38 10.9 2.0 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor SR-25 PF10500.4 CDJ67757.1 - 0.53 9.7 14.8 0.68 9.3 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ67757.1 - 2.7 7.3 8.3 3.2 7.0 5.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF755 PF05501.6 CDJ67757.1 - 2.7 8.0 14.6 3.3 7.7 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Urb2 PF10441.4 CDJ67757.1 - 8.7 5.8 7.1 11 5.5 4.9 1.1 1 0 0 1 1 1 0 Urb2/Npa2 family Ribosomal_60s PF00428.14 CDJ67759.1 - 1.5 9.3 12.9 0.098 13.0 3.2 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.17 CDJ67760.1 - 1.6e-16 59.6 0.0 2.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ67760.1 - 8.5e-13 48.0 0.0 1.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ67760.1 - 4.4e-10 39.2 0.0 6.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 CDJ67761.1 - 2.5e-13 49.5 0.3 3.9e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain PI3_PI4_kinase PF00454.22 CDJ67762.1 - 3.7e-21 75.6 0.1 5e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Acetyltransf_1 PF00583.19 CDJ67762.1 - 6.5e-06 26.0 0.8 2.4e-05 24.2 0.6 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SoxE PF06525.6 CDJ67762.1 - 0.23 10.6 2.7 0.44 9.8 1.9 1.4 1 0 0 1 1 1 0 Sulfocyanin (SoxE) RIC3 PF15361.1 CDJ67762.1 - 0.42 10.8 0.1 0.42 10.8 0.0 2.6 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 SR-25 PF10500.4 CDJ67762.1 - 0.57 9.6 18.4 1.5 8.2 12.7 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDJ67763.1 - 0.0048 15.1 31.9 0.005 15.1 22.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDJ67763.1 - 0.015 14.1 20.2 0.02 13.7 14.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 CDJ67763.1 - 0.09 11.0 30.3 0.1 10.8 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Paf1 PF03985.8 CDJ67763.1 - 0.11 11.2 11.8 0.15 10.7 8.2 1.4 1 0 0 1 1 1 0 Paf1 Herpes_UL95 PF03038.9 CDJ67763.1 - 0.22 10.3 6.8 0.3 9.9 4.7 1.2 1 0 0 1 1 1 0 UL95 family Ycf1 PF05758.7 CDJ67763.1 - 0.22 9.2 10.4 0.25 8.9 7.2 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CDJ67763.1 - 0.24 9.3 8.9 0.24 9.4 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NMDAR2_C PF10565.4 CDJ67763.1 - 0.48 9.0 7.8 0.44 9.1 5.4 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF4045 PF13254.1 CDJ67763.1 - 0.48 9.6 12.4 0.57 9.4 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ndc1_Nup PF09531.5 CDJ67763.1 - 0.5 8.7 9.3 0.64 8.3 6.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Senescence_reg PF04520.8 CDJ67763.1 - 0.99 9.8 10.6 1.7 9.1 7.3 1.4 1 0 0 1 1 1 0 Senescence regulator Hid1 PF12722.2 CDJ67763.1 - 1.5 6.3 11.5 1.4 6.4 8.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHHW PF14286.1 CDJ67763.1 - 1.7 7.9 10.3 1.7 7.8 7.2 1.1 1 0 0 1 1 1 0 DHHW protein TFIIA PF03153.8 CDJ67763.1 - 1.8 8.4 23.1 1.9 8.2 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.14 CDJ67763.1 - 3 5.5 5.5 3.1 5.5 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.6 CDJ67763.1 - 3.6 5.7 16.3 4.6 5.4 11.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Folate_carrier PF01770.13 CDJ67763.1 - 4.3 5.7 6.0 5.3 5.4 4.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF1800 PF08811.6 CDJ67763.1 - 6.4 5.5 14.5 8.3 5.2 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Serinc PF03348.10 CDJ67763.1 - 8 5.0 9.9 9.9 4.7 6.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 CDJ67763.1 - 8.5 3.9 36.5 11 3.5 25.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HEAT PF02985.17 CDJ67764.1 - 0.00033 20.4 19.6 0.00055 19.7 0.1 7.0 7 0 0 7 7 7 1 HEAT repeat Med15 PF09606.5 CDJ67764.1 - 0.0007 17.9 92.0 0.0007 17.9 63.8 7.7 6 2 1 7 7 7 3 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDJ67765.1 - 0.3 10.0 35.4 0.074 12.0 2.0 4.0 4 0 0 4 4 4 0 Fms-interacting protein Neur_chan_memb PF02932.11 CDJ67765.1 - 4.1 7.2 18.1 1.6 8.5 2.7 2.8 1 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region PqqD PF05402.7 CDJ67766.1 - 0.053 13.5 0.3 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF2927 PF11150.3 CDJ67766.1 - 0.077 12.6 4.1 0.082 12.5 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2927) Ctr PF04145.10 CDJ67766.1 - 0.11 12.4 3.6 3 7.8 0.4 2.4 2 0 0 2 2 2 0 Ctr copper transporter family Suf PF05843.9 CDJ67766.1 - 0.15 11.7 3.0 0.55 9.9 0.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DivIC PF04977.10 CDJ67766.1 - 0.16 11.4 13.0 0.08 12.4 3.6 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4131 PF13567.1 CDJ67766.1 - 1.1 8.6 5.3 0.38 10.1 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Asp_protease_2 PF13650.1 CDJ67767.1 - 7.9e-10 39.1 0.0 1.3e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ67767.1 - 2.8e-08 33.4 0.0 5.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ67767.1 - 4.1e-08 33.0 0.0 1.2e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ67767.1 - 5.3e-07 29.6 0.0 9.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ67767.1 - 0.00097 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF3552 PF12072.3 CDJ67767.1 - 0.026 13.7 1.0 0.042 13.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4349 PF14257.1 CDJ67769.1 - 3.1 6.9 9.6 4.1 6.5 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Med3 PF11593.3 CDJ67769.1 - 4.9 6.2 18.9 6 5.9 13.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF726 PF05277.7 CDJ67769.1 - 6.3 5.5 7.9 7.7 5.2 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PsbQ PF05757.6 CDJ67769.1 - 7.2 5.9 9.2 9.3 5.5 6.4 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) PTH2 PF01981.11 CDJ67770.1 - 6.8e-18 64.4 0.0 6.8e-18 64.4 0.0 4.1 2 2 2 4 4 4 1 Peptidyl-tRNA hydrolase PTH2 HTH_23 PF13384.1 CDJ67771.1 - 0.0053 16.3 0.1 0.029 13.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.2 CDJ67771.1 - 0.037 13.6 1.2 0.062 12.9 0.2 1.9 2 0 0 2 2 2 0 MarR family Ribosomal_60s PF00428.14 CDJ67772.1 - 8.3e-25 87.0 13.2 1.3e-24 86.3 9.1 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Totivirus_coat PF05518.6 CDJ67772.1 - 0.04 11.7 2.5 0.045 11.5 1.8 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF3138 PF11336.3 CDJ67772.1 - 0.62 8.1 2.8 0.62 8.1 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FAM222A PF15258.1 CDJ67773.1 - 0.87 8.7 20.5 1.1 8.4 14.2 1.0 1 0 0 1 1 1 0 Protein family of FAM222A eIF3_subunit PF08597.5 CDJ67773.1 - 4.1 6.8 15.1 5.3 6.5 10.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Radical_SAM_N PF08497.5 CDJ67773.1 - 4.4 6.1 9.0 4.7 6.0 6.3 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal AP2 PF00847.15 CDJ67774.1 - 2e-05 24.6 0.2 2e-05 24.6 0.1 4.5 5 0 0 5 5 5 1 AP2 domain Surface_antigen PF11054.3 CDJ67776.1 - 6.6e-18 65.0 0.0 6.9e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Cation_ATPase_N PF00690.21 CDJ67778.1 - 7.6e-15 54.1 0.0 7.6e-15 54.1 0.0 2.7 3 1 0 3 3 3 1 Cation transporter/ATPase, N-terminus PEPCK_ATP PF01293.15 CDJ67779.1 - 9.4e-43 146.4 0.0 1e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase CbtA PF09490.5 CDJ67780.1 - 0.0034 16.7 3.5 0.0045 16.3 2.4 1.1 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) SAC3_GANP PF03399.11 CDJ67780.1 - 0.0079 15.7 5.6 0.014 14.9 3.9 1.7 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family LEDGF PF11467.3 CDJ67780.1 - 0.018 14.7 0.3 0.018 14.7 0.2 2.1 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) RskA PF10099.4 CDJ67780.1 - 0.03 14.0 9.4 0.11 12.2 6.5 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA ACOX PF01756.14 CDJ67780.1 - 0.035 13.4 0.6 0.035 13.4 0.4 1.6 2 0 0 2 2 2 0 Acyl-CoA oxidase Ribosomal_60s PF00428.14 CDJ67780.1 - 0.048 14.0 3.5 0.048 14.0 2.4 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pro-NT_NN PF07421.6 CDJ67780.1 - 0.11 11.9 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor APG6 PF04111.7 CDJ67780.1 - 0.33 9.9 7.5 0.41 9.6 5.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 CDJ67780.1 - 0.33 10.5 4.7 0.43 10.2 3.2 1.1 1 0 0 1 1 1 0 Mnd1 family PilJ PF13675.1 CDJ67780.1 - 0.53 10.6 14.3 0.041 14.2 2.8 2.4 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term WBP-1 PF11669.3 CDJ67780.1 - 0.59 10.2 2.7 0.48 10.5 0.3 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 Suf PF05843.9 CDJ67780.1 - 4.4 6.9 8.5 5.7 6.5 5.9 1.2 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Cyclin_C PF02984.14 CDJ67782.1 - 1.4 8.8 7.9 1.6 8.6 5.5 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain MORN_2 PF07661.8 CDJ67782.1 - 8.8 6.7 10.1 21 5.5 0.2 3.5 2 1 2 4 4 4 0 MORN repeat variant Pox_RNA_Pol_19 PF05320.7 CDJ67782.1 - 9.9 5.8 13.2 10 5.8 9.1 1.0 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RVT_1 PF00078.22 CDJ67784.1 - 9.8e-19 67.5 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pol_alpha_B_N PF08418.5 CDJ67785.1 - 0.51 9.8 6.7 0.74 9.3 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2339 PF10101.4 CDJ67786.1 - 0.22 9.7 2.0 0.26 9.5 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF4259 PF14078.1 CDJ67786.1 - 4.2 7.8 8.2 23 5.4 5.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) FAM60A PF15396.1 CDJ67786.1 - 4.6 6.9 6.2 6.9 6.3 4.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Gly-zipper_OmpA PF13436.1 CDJ67786.1 - 6.8 6.3 33.1 9.7 5.8 22.9 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PGA2 PF07543.7 CDJ67786.1 - 7 6.4 11.5 8.5 6.1 8.0 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Med15 PF09606.5 CDJ67786.1 - 8 4.5 41.3 8.6 4.4 28.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mucin PF01456.12 CDJ67786.1 - 9.6 5.9 16.1 12 5.6 11.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.20 CDJ67787.1 - 8.3e-14 51.3 0.0 1.1e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67787.1 - 4.5e-05 22.6 0.0 6.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Claudin_2 PF13903.1 CDJ67788.1 - 0.083 12.5 1.0 0.097 12.3 0.7 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TraT PF05818.7 CDJ67788.1 - 0.092 12.1 8.7 0.13 11.6 6.1 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Med15 PF09606.5 CDJ67788.1 - 0.44 8.6 11.2 0.45 8.6 7.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MSP1_C PF07462.6 CDJ67788.1 - 0.76 8.0 7.9 0.84 7.9 5.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus R_equi_Vir PF05526.6 CDJ67788.1 - 1.3 8.5 8.7 2 8.0 6.0 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SR-25 PF10500.4 CDJ67788.1 - 3.1 7.2 10.9 4 6.8 7.6 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ67789.1 - 0.052 13.6 9.3 0.081 12.9 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 CDJ67789.1 - 0.28 10.6 14.1 0.28 10.6 9.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PP2C PF00481.16 CDJ67791.1 - 4.7e-17 62.2 0.1 5.2e-17 62.0 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C CDK2AP PF09806.4 CDJ67791.1 - 0.0011 19.2 3.9 0.0012 19.0 2.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein MFMR PF07777.6 CDJ67791.1 - 0.081 12.8 4.5 0.12 12.2 3.1 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR Ald_Xan_dh_C2 PF02738.13 CDJ67791.1 - 0.11 10.7 1.7 0.15 10.3 1.1 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase RAP1 PF07218.6 CDJ67791.1 - 5.2 5.0 5.3 5.1 5.0 3.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PP2C PF00481.16 CDJ67792.1 - 0.0032 16.9 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CDJ67792.1 - 0.037 13.7 2.6 0.17 11.5 1.5 2.0 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) SSP160 PF06933.6 CDJ67792.1 - 2.5 6.0 19.0 7.4 4.4 0.1 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 bZIP_Maf PF03131.12 CDJ67794.1 - 0.014 15.6 7.2 0.023 14.9 1.0 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF4510 PF14971.1 CDJ67794.1 - 0.016 15.3 5.3 0.019 15.1 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Uds1 PF15456.1 CDJ67794.1 - 0.028 14.4 8.1 0.064 13.2 5.5 1.6 1 1 0 1 1 1 0 Up-regulated During Septation GAS PF13851.1 CDJ67794.1 - 0.041 13.0 6.6 0.072 12.2 4.6 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 CDJ67794.1 - 0.042 13.3 8.9 0.051 13.0 6.1 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.6 CDJ67794.1 - 0.056 12.1 2.8 0.067 11.8 2.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Amidohydro_2 PF04909.9 CDJ67794.1 - 0.087 12.3 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase MscS_porin PF12795.2 CDJ67794.1 - 0.088 12.1 15.3 0.14 11.4 10.6 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.6 CDJ67794.1 - 0.091 12.6 3.1 4 7.4 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3855 PF12967.2 CDJ67794.1 - 0.14 11.6 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) APG6 PF04111.7 CDJ67794.1 - 0.15 11.0 4.6 0.19 10.7 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 CDJ67794.1 - 0.45 10.5 7.4 0.39 10.7 1.0 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 CDJ67794.1 - 0.47 10.2 9.9 0.58 10.0 6.9 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1843 PF08898.5 CDJ67794.1 - 0.73 9.9 8.4 0.32 11.0 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) CCDC-167 PF15188.1 CDJ67794.1 - 0.75 9.7 7.9 3 7.8 1.8 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 CDJ67794.1 - 1 8.9 9.2 1.4 8.4 6.4 1.1 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 CDJ67794.1 - 1.7 9.0 6.2 1.5 9.1 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 CDJ67794.1 - 2.1 8.1 7.0 3.2 7.5 0.9 2.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF4140 PF13600.1 CDJ67794.1 - 2.2 8.7 12.8 7.2 7.1 1.2 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 CDJ67794.1 - 2.8 7.5 6.6 5.2 6.6 4.4 1.5 1 1 0 1 1 1 0 Mnd1 family Macoilin PF09726.4 CDJ67794.1 - 6.9 4.8 9.6 30 2.7 6.7 1.8 1 1 0 1 1 1 0 Transmembrane protein DUF904 PF06005.7 CDJ67794.1 - 8.6 6.7 10.4 11 6.4 0.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 CDJ67794.1 - 9.4 6.1 11.6 9.5 6.1 1.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HEAT_2 PF13646.1 CDJ67795.1 - 5.2e-11 42.6 2.3 9.9e-06 25.7 0.2 2.0 1 1 1 2 2 2 2 HEAT repeats PC_rep PF01851.17 CDJ67795.1 - 1e-08 34.9 0.3 0.00049 20.1 0.0 2.9 3 0 0 3 3 3 2 Proteasome/cyclosome repeat HEAT PF02985.17 CDJ67795.1 - 8.2e-07 28.5 1.4 0.085 12.9 0.0 3.8 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 CDJ67795.1 - 0.00045 20.6 3.0 0.039 14.4 0.4 3.1 1 1 2 3 3 3 2 HEAT-like repeat IBN_N PF03810.14 CDJ67795.1 - 0.02 14.7 0.1 3.3 7.6 0.0 2.2 1 1 1 2 2 2 0 Importin-beta N-terminal domain Hemolysin_N PF12563.3 CDJ67796.1 - 0.0071 15.7 0.7 0.0089 15.4 0.5 1.1 1 0 0 1 1 1 1 Hemolytic toxin N terminal DUF4127 PF13552.1 CDJ67796.1 - 0.011 14.1 0.5 0.011 14.1 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4127) DUF2149 PF09919.4 CDJ67796.1 - 0.017 15.2 4.1 0.028 14.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) EphA2_TM PF14575.1 CDJ67796.1 - 0.023 15.0 4.4 0.19 12.1 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LGFP PF08310.6 CDJ67796.1 - 0.034 13.7 0.2 0.078 12.6 0.1 1.7 1 1 0 1 1 1 0 LGFP repeat Isy1 PF06246.7 CDJ67796.1 - 0.083 12.2 7.1 0.088 12.1 4.9 1.1 1 0 0 1 1 1 0 Isy1-like splicing family BCS1_N PF08740.6 CDJ67796.1 - 0.093 12.3 2.4 0.11 12.0 1.7 1.1 1 0 0 1 1 1 0 BCS1 N terminal Protamine_P2 PF00841.14 CDJ67796.1 - 0.28 11.7 21.7 0.46 11.0 4.3 2.2 2 0 0 2 2 2 0 Sperm histone P2 DUF1764 PF08576.5 CDJ67796.1 - 0.39 11.5 7.1 4.2 8.1 0.5 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Folliculin PF11704.3 CDJ67796.1 - 0.52 9.8 6.4 4.5 6.8 0.6 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Tankyrase_bdg_C PF15327.1 CDJ67796.1 - 0.53 10.4 5.3 0.69 10.0 3.7 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain GRP PF07172.6 CDJ67796.1 - 0.59 10.6 3.5 2.5 8.6 0.3 2.1 2 0 0 2 2 2 0 Glycine rich protein family PHD_3 PF13922.1 CDJ67796.1 - 0.79 10.0 16.6 0.69 10.1 2.1 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF4569 PF15133.1 CDJ67796.1 - 1.3 8.3 7.0 1.5 8.1 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) MDFI PF15316.1 CDJ67796.1 - 1.6 8.6 4.5 2 8.3 3.1 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Hid1 PF12722.2 CDJ67796.1 - 2.2 5.8 5.9 2.2 5.8 4.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1183 PF06682.7 CDJ67796.1 - 2.4 7.6 8.1 3.1 7.3 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) CDK2AP PF09806.4 CDJ67796.1 - 2.7 8.1 12.8 3.4 7.8 8.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Neur_chan_memb PF02932.11 CDJ67796.1 - 3.1 7.6 5.8 3.4 7.4 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WWbp PF10349.4 CDJ67796.1 - 3.1 8.7 11.2 4.5 8.1 7.8 1.2 1 0 0 1 1 1 0 WW-domain ligand protein APC_CDC26 PF10471.4 CDJ67796.1 - 4.8 8.0 32.5 0.39 11.4 5.7 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Adaptin_binding PF10199.4 CDJ67796.1 - 5.4 7.2 10.9 7.6 6.8 7.5 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 PAT1 PF09770.4 CDJ67796.1 - 5.4 5.1 32.5 6 4.9 22.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MSA-2c PF12238.3 CDJ67796.1 - 5.5 6.6 10.5 0.63 9.6 0.5 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF3464 PF11947.3 CDJ67796.1 - 6.5 6.1 10.5 17 4.8 7.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) zf-CCHC PF00098.18 CDJ67797.1 - 1e-07 31.5 10.9 4.4e-06 26.3 1.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ67797.1 - 0.0032 17.1 0.3 0.0032 17.1 0.2 2.3 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ67797.1 - 0.0035 16.9 0.6 0.0035 16.9 0.4 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ67797.1 - 0.03 13.9 7.8 0.041 13.5 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ67797.1 - 0.032 14.2 5.7 0.059 13.4 4.0 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.1 CDJ67797.1 - 0.5 9.9 5.8 0.15 11.5 0.7 2.2 1 1 1 2 2 2 0 Zinc knuckle Spt20 PF12090.3 CDJ67798.1 - 0.0072 15.6 5.4 0.47 9.7 0.1 2.1 2 0 0 2 2 2 2 Spt20 family APC_CDC26 PF10471.4 CDJ67798.1 - 0.041 14.6 0.9 0.041 14.6 0.6 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 RAB3GAP2_N PF14655.1 CDJ67798.1 - 0.41 9.6 12.1 0.07 12.1 1.2 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus GN3L_Grn1 PF08701.6 CDJ67798.1 - 1.8 8.5 11.1 0.8 9.6 0.3 2.3 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase NIL PF09383.5 CDJ67798.1 - 3.6 7.2 8.1 0.13 11.8 0.5 2.1 2 0 0 2 2 2 0 NIL domain FimP PF09766.4 CDJ67798.1 - 4.5 6.2 13.8 1.5 7.8 1.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF2489 PF10675.4 CDJ67798.1 - 5.3 6.7 18.2 2.2 7.9 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Suf PF05843.9 CDJ67798.1 - 9.8 5.8 11.1 7.9 6.1 1.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RVT_1 PF00078.22 CDJ67799.1 - 5e-12 45.6 0.0 9.6e-12 44.7 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.3 CDJ67799.1 - 0.033 13.4 0.2 0.045 12.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Retrotrans_gag PF03732.12 CDJ67800.1 - 0.018 15.0 0.1 0.11 12.5 0.0 2.3 2 1 1 3 3 3 0 Retrotransposon gag protein SR-25 PF10500.4 CDJ67802.1 - 0.00076 19.0 5.0 0.00076 19.0 3.5 3.4 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein NUC153 PF08159.7 CDJ67802.1 - 0.0028 17.2 0.3 0.0068 15.9 0.2 1.7 1 0 0 1 1 1 1 NUC153 domain CAF-1_p150 PF11600.3 CDJ67802.1 - 0.0051 16.2 25.0 0.1 11.9 9.0 2.3 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Period_C PF12114.3 CDJ67802.1 - 0.084 12.4 27.9 0.36 10.4 4.0 2.7 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Nop25 PF09805.4 CDJ67802.1 - 0.11 12.5 10.4 0.23 11.5 4.9 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DDRGK PF09756.4 CDJ67804.1 - 0.089 12.1 6.6 0.13 11.6 4.6 1.2 1 0 0 1 1 1 0 DDRGK domain Macoilin PF09726.4 CDJ67804.1 - 0.13 10.5 45.1 0.15 10.2 31.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Utp14 PF04615.8 CDJ67804.1 - 1.1 7.3 28.6 1.3 7.0 19.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 CDJ67804.1 - 1.1 8.3 30.9 1.6 7.9 21.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 CDJ67804.1 - 1.8 7.8 34.8 2.5 7.4 24.1 1.2 1 0 0 1 1 1 0 Vta1 like DUF4175 PF13779.1 CDJ67804.1 - 2 6.0 21.2 2.6 5.6 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nop25 PF09805.4 CDJ67804.1 - 4.5 7.3 15.6 7.6 6.6 10.8 1.5 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) MIP-T3 PF10243.4 CDJ67804.1 - 5.7 5.2 31.9 6.8 5.0 22.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Spc7_N PF15402.1 CDJ67804.1 - 8.3 4.2 49.5 10 4.0 34.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 zf-DHHC PF01529.15 CDJ67805.1 - 1.1e-09 37.9 4.8 5.8e-09 35.5 1.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Suf PF05843.9 CDJ67805.1 - 0.11 12.1 1.9 0.19 11.4 1.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Shisa PF13908.1 CDJ67805.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.5 3 1 0 3 3 3 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 CDJ67805.1 - 4.6 7.7 5.8 1.4 9.3 0.9 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain 14-3-3 PF00244.15 CDJ67806.1 - 1.8e-37 128.6 0.0 2.1e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein PG_binding_1 PF01471.13 CDJ67806.1 - 0.043 13.7 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TPR_14 PF13428.1 CDJ67806.1 - 0.082 13.5 5.0 1.3 9.8 0.3 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Rhomboid PF01694.17 CDJ67807.1 - 0.024 14.6 1.7 0.025 14.6 1.2 1.1 1 0 0 1 1 1 0 Rhomboid family EamA PF00892.15 CDJ67807.1 - 0.042 13.8 4.5 0.05 13.6 3.2 1.1 1 0 0 1 1 1 0 EamA-like transporter family EF-hand_7 PF13499.1 CDJ67810.1 - 1.1e-06 28.6 1.2 2.3e-06 27.6 0.8 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CDJ67810.1 - 3.1e-06 26.0 1.8 4.4e-05 22.4 0.4 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CDJ67810.1 - 1.2e-05 24.7 0.7 0.003 17.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CDJ67810.1 - 7.8e-05 21.8 1.1 0.00018 20.7 0.8 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 CDJ67810.1 - 0.00024 20.6 0.4 0.00041 19.9 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CDJ67810.1 - 0.013 15.5 1.0 0.015 15.3 0.7 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region NuA4 PF09340.5 CDJ67810.1 - 0.073 12.7 1.5 0.11 12.0 1.1 1.5 1 1 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Sporozoite_P67 PF05642.6 CDJ67812.1 - 0.00028 18.8 11.7 0.00045 18.2 8.1 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Macoilin PF09726.4 CDJ67812.1 - 0.0085 14.4 14.9 0.016 13.5 10.3 1.4 1 0 0 1 1 1 1 Transmembrane protein LRV PF01816.12 CDJ67812.1 - 0.082 13.1 0.3 0.082 13.1 0.2 3.7 3 0 0 3 3 3 0 Leucine rich repeat variant Spt20 PF12090.3 CDJ67812.1 - 0.17 11.1 8.5 0.78 9.0 0.3 2.4 2 0 0 2 2 2 0 Spt20 family Otopetrin PF03189.8 CDJ67812.1 - 0.43 9.5 1.7 0.74 8.7 1.2 1.3 1 0 0 1 1 1 0 Otopetrin Lin-8 PF03353.10 CDJ67812.1 - 0.63 9.2 9.2 2.5 7.2 4.0 2.8 3 0 0 3 3 3 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.8 CDJ67812.1 - 1.1 8.7 9.3 3.1 7.2 2.5 2.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DLIC PF05783.6 CDJ67812.1 - 1.3 7.5 7.1 2.8 6.4 4.9 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MACPF PF01823.14 CDJ67812.1 - 1.4 8.5 15.4 26 4.4 0.0 2.4 2 0 0 2 2 2 0 MAC/Perforin domain Neur_chan_memb PF02932.11 CDJ67812.1 - 2.2 8.1 8.3 7.8 6.3 4.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_60s PF00428.14 CDJ67812.1 - 4.1 7.8 41.5 4.1 7.8 7.7 4.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein APC_CDC26 PF10471.4 CDJ67812.1 - 8.9 7.1 32.3 0.39 11.4 10.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 RAP1 PF07218.6 CDJ67812.1 - 9.6 4.1 22.4 14 3.5 15.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Plasmodium_Vir PF05795.6 CDJ67813.1 - 9.8 5.2 7.6 18 4.4 0.2 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF1469 PF07332.6 CDJ67814.1 - 0.00011 21.8 1.4 0.00019 21.1 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) DUF3537 PF12056.3 CDJ67814.1 - 0.013 14.2 0.2 0.015 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) MAPEG PF01124.13 CDJ67814.1 - 0.015 14.8 7.4 0.015 14.8 5.1 2.1 1 1 1 2 2 1 0 MAPEG family Serinc PF03348.10 CDJ67814.1 - 0.02 13.5 1.3 0.024 13.3 0.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.17 CDJ67814.1 - 0.04 12.9 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Gastrin PF00918.12 CDJ67814.1 - 0.25 12.1 16.1 0.35 11.6 11.2 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family COX1 PF00115.15 CDJ67814.1 - 0.36 9.4 2.4 0.4 9.2 1.7 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Cyclin_C PF02984.14 CDJ67814.1 - 0.45 10.4 5.2 0.65 9.9 3.6 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain Peptidase_S49_N PF08496.5 CDJ67814.1 - 0.46 10.2 6.2 0.6 9.9 4.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4106 PF13388.1 CDJ67814.1 - 0.49 9.3 17.7 0.53 9.1 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Herpes_DNAp_acc PF04929.7 CDJ67814.1 - 3.7 6.4 8.9 3.9 6.3 6.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4131 PF13567.1 CDJ67814.1 - 4.1 6.7 10.2 9.9 5.5 7.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) NARP1 PF12569.3 CDJ67814.1 - 4.3 5.9 12.7 5.1 5.7 8.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2371 PF10177.4 CDJ67814.1 - 8 6.3 9.4 22 4.9 6.5 1.8 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) RRM_1 PF00076.17 CDJ67816.1 - 6.8e-14 51.2 0.0 1.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 CDJ67816.1 - 1.4e-09 37.6 6.6 2.5e-09 36.8 4.6 1.4 1 0 0 1 1 1 1 WW domain RRM_6 PF14259.1 CDJ67816.1 - 1.3e-07 31.4 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ67816.1 - 5.5e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) K_channel_TID PF07941.6 CDJ67816.1 - 0.035 14.3 0.7 0.035 14.3 0.5 3.7 5 0 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain Linocin_M18 PF04454.7 CDJ67817.1 - 0.2 10.4 1.1 0.43 9.4 0.8 1.5 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Med15 PF09606.5 CDJ67819.1 - 0.00055 18.2 9.2 0.00055 18.2 6.4 2.9 2 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1344 PF07076.6 CDJ67819.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1344) Spt20 PF12090.3 CDJ67819.1 - 0.022 14.1 0.3 0.022 14.1 0.2 1.5 2 0 0 2 2 2 0 Spt20 family DUF1681 PF07933.9 CDJ67819.1 - 0.065 12.7 2.6 0.12 11.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) ATAD4 PF15321.1 CDJ67819.1 - 0.44 11.5 3.9 7 7.7 0.8 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Activator_LAG-3 PF11498.3 CDJ67819.1 - 5.5 5.6 30.5 2.6 6.6 15.7 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PspB PF06667.7 CDJ67819.1 - 9.3 6.2 6.1 1.3 8.9 0.4 2.2 2 0 0 2 2 2 0 Phage shock protein B PAT1 PF09770.4 CDJ67820.1 - 2.8 6.0 15.7 3.1 5.9 10.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RVP PF00077.15 CDJ67821.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CDJ67821.1 - 0.069 13.2 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein Retrotrans_gag PF03732.12 CDJ67822.1 - 0.00054 19.9 0.1 0.0023 17.9 0.0 2.0 3 0 0 3 3 3 1 Retrotransposon gag protein rve PF00665.21 CDJ67823.1 - 2.8e-15 56.4 0.0 3.3e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ67823.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Sugar-bind PF04198.8 CDJ67823.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain TrmE_N PF10396.4 CDJ67823.1 - 0.14 12.1 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus RVT_1 PF00078.22 CDJ67824.1 - 5.5e-10 38.9 0.0 1.3e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3552 PF12072.3 CDJ67824.1 - 0.091 11.9 1.0 0.13 11.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Peptidase_M50B PF13398.1 CDJ67825.1 - 0.1 12.0 0.3 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Ribosomal_60s PF00428.14 CDJ67825.1 - 0.31 11.4 8.3 1.3 9.4 3.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Utp14 PF04615.8 CDJ67825.1 - 0.41 8.7 66.6 0.51 8.4 46.2 1.0 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.4 CDJ67826.1 - 0.83 7.8 8.1 0.69 8.0 5.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDJ67826.1 - 2.6 5.6 8.7 2.5 5.7 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Androgen_recep PF02166.11 CDJ67826.1 - 2.9 6.6 7.0 2.7 6.7 4.9 1.1 1 0 0 1 1 1 0 Androgen receptor BAF1_ABF1 PF04684.8 CDJ67826.1 - 7.6 5.2 10.3 8 5.1 7.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pribosyltran_N PF13793.1 CDJ67827.1 - 2.4e-46 156.2 0.2 3.6e-45 152.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CDJ67827.1 - 1.4e-21 77.1 0.2 2.9e-21 76.0 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CDJ67827.1 - 2.6e-10 40.1 0.4 7.6e-10 38.5 0.3 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CDJ67827.1 - 0.0014 17.9 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Med15 PF09606.5 CDJ67829.1 - 0.014 13.6 29.9 0.018 13.2 20.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ67829.1 - 0.056 11.6 23.1 0.065 11.4 16.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDJ67829.1 - 1 9.0 4.9 1.5 8.4 3.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ67829.1 - 4.7 6.9 15.9 5.9 6.6 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MSP1_C PF07462.6 CDJ67829.1 - 8.6 4.6 8.5 14 3.8 5.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RVT_1 PF00078.22 CDJ67830.1 - 3.5e-10 39.5 0.0 6.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CDJ67830.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like PH PF00169.24 CDJ67831.1 - 5.1e-05 23.4 1.5 0.00012 22.2 1.0 1.6 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CDJ67831.1 - 0.0021 18.3 0.3 0.0036 17.5 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Mito_fiss_reg PF05308.6 CDJ67831.1 - 2.6 7.3 6.3 4.4 6.6 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Rifin_STEVOR PF02009.11 CDJ67831.1 - 4.5 6.8 11.0 7.5 6.1 7.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family PAT1 PF09770.4 CDJ67832.1 - 0.11 10.6 109.4 0.14 10.3 75.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 CDJ67833.1 - 0.048 13.0 6.0 0.071 12.4 4.2 1.4 1 0 0 1 1 1 0 Spt20 family Ribosomal_60s PF00428.14 CDJ67833.1 - 0.08 13.3 24.5 1.5 9.2 8.5 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Med15 PF09606.5 CDJ67833.1 - 0.42 8.7 31.1 0.0054 15.0 15.5 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDJ67833.1 - 1.3 8.0 19.1 2.1 7.3 13.3 1.3 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDJ67833.1 - 1.4 8.6 15.3 0.69 9.5 8.7 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1470 PF07336.6 CDJ67833.1 - 2.4 8.4 18.2 4.5 7.5 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) XRCC4 PF06632.7 CDJ67833.1 - 3.7 6.3 12.0 0.54 9.0 5.3 1.8 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF508 PF04370.7 CDJ67833.1 - 8.2 6.0 10.9 2 8.0 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Apt1 PF10351.4 CDJ67833.1 - 8.5 5.1 19.1 2.5 6.8 8.9 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Spt20 PF12090.3 CDJ67834.1 - 5.6 6.2 21.5 1.3 8.2 1.3 4.4 4 0 0 4 4 4 0 Spt20 family DivIC PF04977.10 CDJ67835.1 - 0.0041 16.5 3.9 0.0052 16.2 2.7 1.2 1 0 0 1 1 1 1 Septum formation initiator DUF1980 PF09323.5 CDJ67835.1 - 0.019 14.7 1.2 0.021 14.5 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PSK PF06404.7 CDJ67835.1 - 0.049 14.4 0.9 0.08 13.7 0.6 1.4 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) G0-G1_switch_2 PF15103.1 CDJ67835.1 - 0.068 13.3 3.3 0.084 13.0 2.3 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 Cellulase-like PF12876.2 CDJ67835.1 - 0.071 13.5 0.6 0.1 13.0 0.4 1.3 1 1 0 1 1 1 0 Sugar-binding cellulase-like FimP PF09766.4 CDJ67835.1 - 0.12 11.3 7.9 0.15 11.0 5.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF3408 PF11888.3 CDJ67835.1 - 0.3 10.9 2.9 0.32 10.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Serinc PF03348.10 CDJ67835.1 - 0.34 9.5 1.6 0.36 9.4 1.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) EPL1 PF10513.4 CDJ67835.1 - 0.42 10.8 4.2 0.5 10.6 2.9 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Spt20 PF12090.3 CDJ67835.1 - 0.43 9.8 4.5 0.44 9.8 3.1 1.2 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.4 CDJ67835.1 - 0.44 8.7 13.7 0.39 8.9 9.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDJ67835.1 - 0.8 9.3 7.6 0.81 9.3 5.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Androgen_recep PF02166.11 CDJ67835.1 - 0.89 8.3 11.0 1 8.1 7.6 1.3 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.8 CDJ67835.1 - 0.98 9.2 10.6 1 9.1 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD_3 PF13922.1 CDJ67835.1 - 2.3 8.5 6.2 1 9.6 2.9 1.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF4106 PF13388.1 CDJ67835.1 - 5 5.9 11.0 4.7 6.0 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SR-25 PF10500.4 CDJ67835.1 - 6 6.2 14.9 0.85 9.0 2.0 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3138 PF11336.3 CDJ67835.1 - 7.3 4.6 10.1 8.2 4.4 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RNase_Zc3h12a PF11977.3 CDJ67836.1 - 5.8e-18 65.2 8.7 2.5e-17 63.1 0.2 3.4 2 2 0 2 2 2 1 Zc3h12a-like Ribonuclease NYN domain DUF755 PF05501.6 CDJ67836.1 - 2.6e-05 24.2 36.3 2.6e-05 24.2 25.1 8.6 7 2 0 8 8 8 1 Domain of unknown function (DUF755) Med15 PF09606.5 CDJ67836.1 - 1.2 7.2 103.6 0.0059 14.8 3.3 2.6 2 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RRM_1 PF00076.17 CDJ67838.1 - 4.4e-24 83.9 0.1 9.1e-12 44.4 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ67838.1 - 7e-23 80.4 1.7 1e-10 41.4 0.0 5.2 5 0 0 5 5 5 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ67838.1 - 6.7e-09 35.4 0.0 0.0025 17.6 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1517 PF07466.6 CDJ67839.1 - 0.034 13.1 0.3 0.048 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF4653 PF15546.1 CDJ67839.1 - 0.035 13.3 5.0 0.056 12.7 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Myco_19_kDa PF05481.7 CDJ67839.1 - 0.095 12.5 2.0 0.13 12.1 1.4 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen DUF4228 PF14009.1 CDJ67839.1 - 0.65 10.1 8.0 0.99 9.5 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF1645 PF07816.6 CDJ67839.1 - 1.1 9.7 16.3 1.8 8.9 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) PBP_sp32 PF07222.7 CDJ67839.1 - 1.3 8.0 5.6 0.22 10.6 1.3 1.5 1 1 1 2 2 2 0 Proacrosin binding protein sp32 FSIP1 PF15554.1 CDJ67839.1 - 2 7.1 10.4 2.6 6.7 7.2 1.1 1 0 0 1 1 1 0 FSIP1 family DUF515 PF04415.7 CDJ67839.1 - 2.1 6.4 7.2 3.2 5.9 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Corona_nucleoca PF00937.13 CDJ67839.1 - 3.9 6.3 10.5 5.6 5.8 7.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein dsDNA_bind PF01984.15 CDJ67840.1 - 0.0054 16.7 10.8 0.0057 16.6 7.5 1.3 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Med15 PF09606.5 CDJ67840.1 - 0.0087 14.3 17.9 0.0069 14.6 12.4 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_coat_CotO PF14153.1 CDJ67840.1 - 0.048 13.1 6.6 0.04 13.3 4.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Spt20 PF12090.3 CDJ67840.1 - 0.078 12.3 7.5 0.067 12.5 5.2 1.2 1 0 0 1 1 1 0 Spt20 family BRF1 PF07741.8 CDJ67840.1 - 0.11 12.7 3.4 0.1 12.8 2.4 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PBP1_TM PF14812.1 CDJ67840.1 - 0.11 12.7 1.7 0.14 12.4 1.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tim54 PF11711.3 CDJ67840.1 - 0.16 10.5 2.5 0.15 10.5 1.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.5 CDJ67840.1 - 0.19 11.4 2.5 0.21 11.3 1.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Gag_spuma PF03276.9 CDJ67840.1 - 0.54 8.5 13.3 0.44 8.8 9.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein eIF-3_zeta PF05091.7 CDJ67840.1 - 1.1 7.7 6.7 1 7.9 4.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4557 PF15101.1 CDJ67840.1 - 1.2 8.9 13.9 1.3 8.7 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CDK2AP PF09806.4 CDJ67840.1 - 1.3 9.2 8.7 1.6 8.9 6.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SAGA-Tad1 PF12767.2 CDJ67840.1 - 1.3 8.5 8.4 1.5 8.4 5.8 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Band_3_cyto PF07565.8 CDJ67840.1 - 1.5 8.2 5.2 1.3 8.5 3.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Plasmodium_Vir PF05795.6 CDJ67840.1 - 1.7 7.7 3.7 1.7 7.8 2.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ctr PF04145.10 CDJ67840.1 - 1.9 8.5 4.4 1.9 8.5 3.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.4 CDJ67840.1 - 2.9 6.0 18.9 2.9 6.0 13.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 CDJ67840.1 - 3 7.5 6.9 2.9 7.5 4.8 1.2 1 0 0 1 1 1 0 AUX/IAA family Suf PF05843.9 CDJ67840.1 - 4.1 7.0 12.1 4.1 7.0 8.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3260 PF11658.3 CDJ67840.1 - 4.6 5.2 5.9 4.4 5.3 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) RED_N PF07808.8 CDJ67840.1 - 4.9 6.2 13.0 5.5 6.1 9.0 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Hid1 PF12722.2 CDJ67840.1 - 5.2 4.6 6.8 4.6 4.7 4.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex16 PF08610.5 CDJ67840.1 - 6 5.7 6.4 5.2 5.9 4.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) eIF3_subunit PF08597.5 CDJ67840.1 - 8 5.9 10.6 9.1 5.7 7.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spore_coat_CotO PF14153.1 CDJ67841.1 - 0.023 14.1 9.6 0.025 14.0 6.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SPX PF03105.14 CDJ67841.1 - 0.03 14.0 5.9 0.029 14.1 4.1 1.1 1 0 0 1 1 1 0 SPX domain SprA-related PF12118.3 CDJ67841.1 - 0.081 12.2 32.8 0.11 11.8 22.7 1.0 1 0 0 1 1 1 0 SprA-related family Suf PF05843.9 CDJ67841.1 - 0.12 12.1 13.4 0.13 11.9 9.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDJ67841.1 - 0.17 11.2 17.1 0.17 11.2 11.9 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 CDJ67841.1 - 0.25 11.2 23.2 0.26 11.1 16.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spc7_N PF15402.1 CDJ67841.1 - 0.26 9.2 13.9 0.26 9.2 9.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Presenilin PF01080.12 CDJ67841.1 - 0.36 9.6 7.6 0.38 9.5 5.2 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.5 CDJ67841.1 - 0.37 9.1 10.6 0.41 9.0 7.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.2 CDJ67841.1 - 0.5 7.9 13.4 0.53 7.8 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_U57 PF05582.7 CDJ67841.1 - 0.51 9.2 4.3 0.59 9.0 3.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF4407 PF14362.1 CDJ67841.1 - 0.99 8.3 12.3 1 8.2 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2201_N PF13203.1 CDJ67841.1 - 1 8.4 13.0 1.2 8.2 9.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain AUX_IAA PF02309.11 CDJ67841.1 - 1.2 8.8 9.5 1.4 8.6 6.6 1.1 1 0 0 1 1 1 0 AUX/IAA family RP-C_C PF11800.3 CDJ67841.1 - 1.4 8.5 11.6 1.9 8.1 8.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PAT1 PF09770.4 CDJ67841.1 - 1.7 6.7 29.1 1.8 6.7 20.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 CDJ67841.1 - 1.8 8.0 9.3 2.3 7.6 6.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDK5_activator PF03261.10 CDJ67841.1 - 2.2 7.5 13.5 2.6 7.3 9.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Med15 PF09606.5 CDJ67841.1 - 3 5.9 34.2 3.6 5.6 23.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 CDJ67841.1 - 3.4 5.8 11.5 3.8 5.6 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Paramyxo_ncap PF00973.14 CDJ67841.1 - 5.1 5.6 9.0 4.7 5.7 6.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Dicty_REP PF05086.7 CDJ67841.1 - 5.3 4.6 13.2 5.9 4.5 9.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S49_N PF08496.5 CDJ67841.1 - 5.6 6.7 9.2 8.2 6.2 6.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 CDJ67841.1 - 6.1 6.6 9.3 6.3 6.6 6.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 CDJ67841.1 - 8.2 5.1 12.0 10 4.8 8.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DOR PF14839.1 CDJ67841.1 - 9.8 5.8 22.3 13 5.4 15.5 1.1 1 0 0 1 1 1 0 DOR family Pro_isomerase PF00160.16 CDJ67842.1 - 6.1e-41 140.2 0.3 1.1e-40 139.4 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CDJ67842.1 - 1.2e-08 34.4 1.0 3e-08 33.1 0.6 1.8 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 CDJ67842.1 - 2.5e-07 31.1 3.6 2.5e-07 31.1 2.5 2.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ67842.1 - 4.4e-06 26.0 1.2 0.029 13.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ67842.1 - 9.9e-05 21.9 7.1 0.069 13.1 0.1 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ67842.1 - 0.00053 20.3 4.3 0.036 14.7 0.6 3.1 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ67842.1 - 0.00065 19.7 0.5 0.034 14.3 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat EIF4E-T PF10477.4 CDJ67842.1 - 0.00067 18.5 3.0 0.00072 18.4 2.1 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Pex14_N PF04695.8 CDJ67842.1 - 0.0007 19.6 3.9 0.0012 18.9 2.7 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Utp11 PF03998.8 CDJ67842.1 - 0.0046 16.8 4.1 0.0046 16.8 2.8 2.0 2 0 0 2 2 2 1 Utp11 protein PAT1 PF09770.4 CDJ67842.1 - 0.38 8.9 22.3 0.52 8.4 15.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4199 PF13858.1 CDJ67842.1 - 1.5 8.7 3.5 2.9 7.7 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RNA_pol_Rpb4 PF03874.11 CDJ67842.1 - 2.4 8.1 9.4 1.8 8.5 4.6 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF106 PF01956.11 CDJ67842.1 - 10 5.6 9.2 20 4.7 6.4 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Abi PF02517.11 CDJ67843.1 - 7.3e-10 38.8 3.3 1.9e-09 37.5 0.0 2.8 1 1 1 2 2 2 1 CAAX protease self-immunity CDC37_N PF03234.9 CDJ67843.1 - 0.51 10.6 4.4 0.73 10.1 3.0 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Viral_Beta_CD PF04530.7 CDJ67843.1 - 3.4 7.8 6.9 0.3 11.2 0.9 2.1 2 0 0 2 2 2 0 Viral Beta C/D like family Phage_Gp23 PF10669.4 CDJ67843.1 - 5.4 7.1 5.7 9.8 6.3 3.9 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Activator_LAG-3 PF11498.3 CDJ67843.1 - 6.6 5.3 22.7 13 4.3 15.8 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDJ67843.1 - 9.3 4.3 29.4 0.57 8.3 11.9 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Bromodomain PF00439.20 CDJ67844.1 - 4.4e-17 61.7 0.1 8.6e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DoxX_3 PF13781.1 CDJ67846.1 - 0.07 13.4 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 DoxX-like family TSA PF03249.8 CDJ67846.1 - 2.1 6.7 9.0 3.2 6.1 6.3 1.2 1 0 0 1 1 1 0 Type specific antigen DUF1645 PF07816.6 CDJ67847.1 - 0.0079 16.6 10.0 0.011 16.1 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Herpes_UL87 PF03043.9 CDJ67847.1 - 0.56 8.5 7.7 0.66 8.2 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family FimP PF09766.4 CDJ67847.1 - 1.4 7.8 28.1 0.07 12.1 7.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein PLA2_B PF01735.13 CDJ67847.1 - 1.8 6.5 7.7 0.76 7.8 0.7 2.0 1 1 1 2 2 2 0 Lysophospholipase catalytic domain Rxt3 PF08642.5 CDJ67847.1 - 2.3 8.4 5.6 14 5.9 0.6 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 NinG PF05766.7 CDJ67847.1 - 2.5 7.8 13.7 1.2 8.7 3.4 2.1 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Hex_IIIa PF02455.11 CDJ67847.1 - 2.7 6.5 13.4 3.3 6.2 9.3 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Ribosomal_S26e PF01283.14 CDJ67847.1 - 3.1 8.0 10.3 0.12 12.5 0.5 2.1 2 0 0 2 2 2 0 Ribosomal protein S26e CDK2AP PF09806.4 CDJ67847.1 - 3.3 7.8 24.6 5 7.3 17.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Parvo_coat PF00740.13 CDJ67847.1 - 3.5 6.4 17.9 4.3 6.1 12.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 BRF1 PF07741.8 CDJ67847.1 - 3.5 7.8 14.1 8.7 6.6 0.3 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Hep_59 PF07052.6 CDJ67847.1 - 4.7 7.6 16.2 5.7 7.3 2.4 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Cas_NE0113 PF09623.5 CDJ67847.1 - 4.9 6.5 8.9 8.1 5.8 0.7 2.1 2 0 0 2 2 2 0 CRISPR-associated protein NE0113 (Cas_NE0113) FCP1_C PF09309.5 CDJ67847.1 - 8.8 5.5 24.5 1.6 7.9 4.0 2.1 2 0 0 2 2 2 0 FCP1, C-terminal FimP PF09766.4 CDJ67848.1 - 0.0047 16.0 4.1 0.0047 16.0 2.8 4.7 5 0 0 5 5 5 3 Fms-interacting protein SOBP PF15279.1 CDJ67848.1 - 1.6 9.0 35.8 0.82 9.9 0.7 3.2 3 0 0 3 3 3 0 Sine oculis-binding protein DUF3357 PF11837.3 CDJ67849.1 - 0.039 13.8 1.6 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF3530 PF12048.3 CDJ67849.1 - 1.2 8.0 4.1 20 4.0 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) IBN_N PF03810.14 CDJ67850.1 - 1.1e-05 25.1 0.1 1.1e-05 25.1 0.1 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.17 CDJ67850.1 - 0.0083 16.1 9.2 1 9.6 0.0 4.8 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CDJ67850.1 - 0.024 14.9 7.3 7.8 6.8 0.1 3.6 3 1 1 4 4 4 0 HEAT repeats HEAT_EZ PF13513.1 CDJ67850.1 - 4.3 7.9 8.3 40 4.8 0.1 4.4 3 1 2 5 5 5 0 HEAT-like repeat Peptidase_S8 PF00082.17 CDJ67851.1 - 5.1e-14 52.0 0.2 6.9e-06 25.4 0.0 2.4 3 0 0 3 3 3 2 Subtilase family Zn_peptidase PF04228.8 CDJ67851.1 - 0.0031 16.7 1.1 0.0049 16.1 0.7 1.3 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase FimP PF09766.4 CDJ67851.1 - 0.0037 16.3 5.9 0.0048 16.0 4.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein Pex14_N PF04695.8 CDJ67851.1 - 0.0059 16.6 4.5 0.011 15.7 3.1 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 CDJ67851.1 - 0.01 15.1 0.9 0.013 14.8 0.6 1.2 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.1 CDJ67851.1 - 0.035 13.0 2.3 0.046 12.7 1.6 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4175 PF13779.1 CDJ67851.1 - 0.1 10.2 15.8 0.13 9.8 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 CDJ67851.1 - 0.12 12.1 4.6 0.15 11.7 3.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DivIC PF04977.10 CDJ67851.1 - 0.12 11.8 13.2 0.22 11.0 9.2 1.3 1 0 0 1 1 1 0 Septum formation initiator OATP PF03137.15 CDJ67851.1 - 0.17 9.8 0.4 0.24 9.4 0.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family BRF1 PF07741.8 CDJ67851.1 - 0.22 11.7 4.5 0.31 11.2 3.1 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain RED_N PF07808.8 CDJ67851.1 - 0.26 10.4 8.2 0.35 10.0 5.7 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region FCP1_C PF09309.5 CDJ67851.1 - 1.2 8.4 5.6 2 7.6 3.9 1.3 1 0 0 1 1 1 0 FCP1, C-terminal PHD_3 PF13922.1 CDJ67851.1 - 2.1 8.6 7.2 3.7 7.8 5.0 1.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF788 PF05620.6 CDJ67851.1 - 3.1 7.6 6.9 5.5 6.8 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) PAN_4 PF14295.1 CDJ67852.1 - 1.1e-13 50.6 9.1 2.1e-06 27.3 1.9 2.5 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.21 CDJ67852.1 - 1.9e-09 37.1 1.3 4.3e-05 23.1 0.2 2.8 2 0 0 2 2 2 2 PAN domain ECR1_N PF14382.1 CDJ67853.1 - 0.13 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region rve PF00665.21 CDJ67854.1 - 3.7e-21 75.4 0.0 6.4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDJ67854.1 - 0.0095 15.3 0.9 0.0095 15.3 0.6 1.7 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 CDJ67854.1 - 0.025 14.0 1.0 0.3 10.6 0.0 2.6 3 0 0 3 3 3 0 Integrase core domain PPDK_N PF01326.14 CDJ67855.1 - 2.1e-25 89.4 0.0 2.3e-23 82.7 0.0 3.6 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain IBR PF01485.16 CDJ67856.1 - 3e-16 59.0 33.3 1.6e-08 34.3 4.1 3.9 4 1 0 4 4 4 2 IBR domain Surface_antigen PF11054.3 CDJ67858.1 - 3.6e-76 255.8 4.6 4e-76 255.7 3.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF2296 PF10058.4 CDJ67858.1 - 0.13 12.0 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Isy1 PF06246.7 CDJ67859.1 - 1.8e-07 30.8 0.0 1.9e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family OMP_b-brl PF13505.1 CDJ67860.1 - 3.9 7.3 12.9 7 6.5 9.0 1.5 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Ribosomal_S5 PF00333.15 CDJ67861.1 - 1.3e-07 31.2 0.1 3.9e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PRP38 PF03371.10 CDJ67862.1 - 9.1e-47 158.8 0.1 1.5e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 PRP38 family S1 PF00575.18 CDJ67862.1 - 0.02 14.9 0.0 0.064 13.3 0.0 1.8 1 0 0 1 1 1 0 S1 RNA binding domain IMCp PF12314.3 CDJ67863.1 - 1.2e-14 54.2 59.3 1.1e-09 38.3 16.4 6.1 2 1 4 6 6 6 3 Inner membrane complex protein AlaDh_PNT_C PF01262.16 CDJ67863.1 - 2 7.9 12.0 0.45 10.0 2.2 2.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain N2227 PF07942.7 CDJ67865.1 - 7.8e-77 257.8 0.0 9.4e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.7 CDJ67865.1 - 0.039 14.4 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF228 PF02989.9 CDJ67866.1 - 3.3 7.2 7.0 4 6.9 4.9 1.3 1 0 0 1 1 1 0 Lyme disease proteins of unknown function DUF3347 PF11827.3 CDJ67866.1 - 8.6 6.3 19.4 9.8 6.1 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) KASH PF10541.4 CDJ67867.1 - 0.029 14.1 0.1 0.078 12.8 0.1 1.7 1 0 0 1 1 1 0 Nuclear envelope localisation domain KH_1 PF00013.24 CDJ67867.1 - 0.031 13.9 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 KH domain SNF2_N PF00176.18 CDJ67869.1 - 2e-20 72.8 0.1 3.1e-09 36.0 0.0 2.9 1 1 1 2 2 2 2 SNF2 family N-terminal domain Suf PF05843.9 CDJ67869.1 - 0.024 14.3 0.0 0.024 14.3 0.0 6.1 6 0 0 6 6 6 0 Suppressor of forked protein (Suf) Helicase_C PF00271.26 CDJ67869.1 - 0.3 10.9 0.0 0.3 10.9 0.0 3.7 4 1 0 4 4 4 0 Helicase conserved C-terminal domain APC_CDC26 PF10471.4 CDJ67870.1 - 8.7 7.1 15.0 4.6 8.0 4.4 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PAT1 PF09770.4 CDJ67871.1 - 3.8 5.6 25.6 0.33 9.1 14.4 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 CDJ67872.1 - 0.0021 17.0 9.0 0.0021 17.0 6.3 15.1 5 3 8 13 13 13 1 BAF1 / ABF1 chromatin reorganising factor Asp_protease_2 PF13650.1 CDJ67874.1 - 5.8e-10 39.5 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ67874.1 - 9.9e-09 34.9 0.1 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ67874.1 - 7.7e-06 25.7 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ67874.1 - 0.00076 19.4 0.0 0.0035 17.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ67874.1 - 0.00083 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Gp_dh_C PF02800.15 CDJ67875.1 - 6.3 6.2 6.5 2.5 7.5 2.8 1.5 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain SOG2 PF10428.4 CDJ67876.1 - 0.14 10.7 7.5 0.16 10.5 5.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Corona_nucleoca PF00937.13 CDJ67876.1 - 8.2 5.2 10.3 12 4.7 7.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FAM92 PF06730.6 CDJ67877.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 FAM92 protein zf-CCCH PF00642.19 CDJ67878.1 - 3.3e-09 36.2 28.1 0.0028 17.3 4.5 4.0 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CDJ67878.1 - 0.042 13.8 0.3 0.042 13.8 0.2 3.2 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type CDK2AP PF09806.4 CDJ67880.1 - 0.022 15.0 10.3 0.031 14.4 7.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2392 PF10288.4 CDJ67880.1 - 0.023 15.0 0.1 0.057 13.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) Tir_receptor_N PF07490.6 CDJ67880.1 - 0.037 13.6 0.4 0.055 13.0 0.3 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus ATP_bind_3 PF01171.15 CDJ67880.1 - 0.082 12.3 1.0 2.1 7.8 0.0 2.4 3 0 0 3 3 3 0 PP-loop family Sec3_C PF09763.4 CDJ67880.1 - 0.2 9.7 4.8 0.25 9.4 3.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 APC_CDC26 PF10471.4 CDJ67880.1 - 0.47 11.2 22.2 0.28 11.9 8.9 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 SR-25 PF10500.4 CDJ67880.1 - 3.7 6.9 20.7 7.4 5.9 14.3 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ctr PF04145.10 CDJ67880.1 - 3.9 7.5 7.3 12 5.9 5.0 1.8 1 1 0 1 1 1 0 Ctr copper transporter family DUF4557 PF15101.1 CDJ67880.1 - 8.5 6.1 9.6 1.4 8.7 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Dehydrin PF00257.14 CDJ67880.1 - 9.1 6.6 13.0 0.4 11.0 4.7 1.8 2 0 0 2 2 2 0 Dehydrin Peptidase_M66 PF10462.4 CDJ67881.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 SR-25 PF10500.4 CDJ67882.1 - 0.024 14.1 5.4 0.031 13.7 3.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ67882.1 - 0.12 12.4 6.2 0.17 11.9 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) K_channel_TID PF07941.6 CDJ67882.1 - 2.5 8.3 7.0 2.8 8.2 0.1 2.5 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Helicase_C PF00271.26 CDJ67883.1 - 2.2e-07 30.6 0.0 2.2e-07 30.6 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Herpes_UL87 PF03043.9 CDJ67883.1 - 0.04 12.3 4.9 0.11 10.9 3.4 1.6 1 1 0 1 1 1 0 Herpesvirus UL87 family DUF605 PF04652.11 CDJ67883.1 - 0.063 12.6 35.8 0.53 9.6 21.3 2.1 2 0 0 2 2 2 0 Vta1 like PAT1 PF09770.4 CDJ67883.1 - 0.58 8.3 70.0 0.1 10.8 38.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CDK2AP PF09806.4 CDJ67884.1 - 0.0011 19.2 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CDJ67884.1 - 0.05 13.0 1.8 0.072 12.5 1.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RskA PF10099.4 CDJ67885.1 - 0.027 14.1 16.3 0.039 13.7 11.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Med15 PF09606.5 CDJ67885.1 - 3.7 5.6 49.9 4 5.5 34.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2522 PF10747.4 CDJ67885.1 - 5.5 7.0 11.1 9.2 6.3 7.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2522) Retrotrans_gag PF03732.12 CDJ67887.1 - 2.4e-05 24.2 0.0 3.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein S6PP PF05116.8 CDJ67889.1 - 0.015 14.5 0.2 0.085 12.1 0.3 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase VASP_tetra PF08776.6 CDJ67889.1 - 0.25 10.6 1.3 0.38 10.1 0.2 1.9 2 0 0 2 2 2 0 VASP tetramerisation domain Hydrolase_4 PF12146.3 CDJ67891.1 - 1.9e-05 24.4 0.2 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_5 PF12695.2 CDJ67891.1 - 0.00012 21.8 0.5 0.00012 21.8 0.4 5.6 5 2 0 5 5 5 2 Alpha/beta hydrolase family DUF3458 PF11940.3 CDJ67892.1 - 1.3e-84 284.1 8.8 2.8e-62 210.7 4.9 7.5 8 0 0 8 8 8 2 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 CDJ67892.1 - 5.5e-31 108.0 0.0 5.5e-31 108.0 0.0 2.3 3 0 0 3 3 3 1 Peptidase family M1 NUC173 PF08161.7 CDJ67892.1 - 5.4e-13 48.7 0.1 1.1e-11 44.4 0.0 3.5 2 0 0 2 2 2 1 NUC173 domain BAF1_ABF1 PF04684.8 CDJ67892.1 - 0.00057 18.8 19.4 0.00057 18.8 13.4 17.6 16 5 2 20 20 20 2 BAF1 / ABF1 chromatin reorganising factor Spore_YtfJ PF09579.5 CDJ67892.1 - 1.4 8.8 3.2 1.9 8.3 0.1 3.0 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Far-17a_AIG1 PF04750.9 CDJ67892.1 - 2.9 6.9 0.0 5.8 6.0 0.0 1.4 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein DEC-1_N PF04625.8 CDJ67893.1 - 0.67 8.5 0.0 0.67 8.5 0.0 1.9 1 1 1 2 2 2 0 DEC-1 protein, N-terminal region TEX13 PF15186.1 CDJ67894.1 - 0.038 13.5 3.3 0.063 12.8 2.3 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DivIC PF04977.10 CDJ67894.1 - 4.4 6.8 7.1 2.3 7.7 1.2 2.2 1 1 1 2 2 2 0 Septum formation initiator MAS20 PF02064.10 CDJ67895.1 - 0.00076 19.3 0.2 0.00076 19.3 0.1 2.6 3 0 0 3 3 2 1 MAS20 protein import receptor SAPS PF04499.10 CDJ67895.1 - 0.015 14.0 0.0 0.033 12.8 0.0 1.6 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Kei1 PF08552.6 CDJ67895.1 - 0.019 14.6 0.3 0.019 14.6 0.2 2.8 2 1 0 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 7tm_1 PF00001.16 CDJ67895.1 - 0.038 13.1 0.1 0.038 13.1 0.1 1.8 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DcuC PF03606.10 CDJ67895.1 - 0.055 11.7 1.7 0.13 10.4 0.1 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Ctr PF04145.10 CDJ67895.1 - 0.056 13.4 10.6 0.12 12.4 0.0 3.1 2 1 1 3 3 3 0 Ctr copper transporter family DUF4179 PF13786.1 CDJ67895.1 - 0.074 13.2 0.2 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF4367 PF14285.1 CDJ67895.1 - 0.22 10.8 0.0 6.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) DUF2512 PF10710.4 CDJ67895.1 - 1 8.8 4.2 0.6 9.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) SpoIIIAH PF12685.2 CDJ67895.1 - 1.7 8.0 0.0 1.7 8.0 0.0 3.0 2 1 1 3 3 2 0 SpoIIIAH-like protein DUF2215 PF10225.4 CDJ67895.1 - 5.7 6.3 5.2 5.2 6.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) rve PF00665.21 CDJ67896.1 - 1.2e-05 25.4 0.0 1.2e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDJ67897.1 - 9.2e-15 54.0 0.0 2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RanBP PF00641.13 CDJ67898.1 - 0.00045 19.2 14.2 0.057 12.5 3.8 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 CDJ67898.1 - 0.016 15.0 12.5 0.13 12.1 0.4 2.9 2 1 0 2 2 2 0 Double zinc ribbon Tnp_zf-ribbon_2 PF13842.1 CDJ67898.1 - 1.4 9.3 11.2 7.7 7.0 1.4 2.6 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon GCC2_GCC3 PF07699.8 CDJ67898.1 - 3.5 7.2 10.3 4.1 7.0 1.3 2.9 2 0 0 2 2 2 0 GCC2 and GCC3 EF-hand_7 PF13499.1 CDJ67899.1 - 2.7e-09 37.0 0.2 0.0014 18.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDJ67899.1 - 8.1e-09 34.1 1.0 0.00047 19.2 0.2 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CDJ67899.1 - 8.4e-09 34.5 1.2 0.0034 17.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CDJ67899.1 - 2.6e-06 26.4 3.2 0.017 14.4 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CDJ67899.1 - 0.00013 21.4 0.2 0.06 12.9 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 CDJ67899.1 - 0.012 15.5 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_like PF09279.6 CDJ67899.1 - 0.067 13.2 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like MSP1_C PF07462.6 CDJ67899.1 - 4.4 5.5 6.9 6.6 5.0 4.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pkinase PF00069.20 CDJ67901.1 - 1.9e-08 33.7 0.0 3.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67901.1 - 0.00071 18.7 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDJ67902.1 - 5.5e-14 51.9 0.4 6e-10 38.7 0.0 3.8 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ67902.1 - 2e-08 33.6 0.0 4.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_60s PF00428.14 CDJ67902.1 - 0.00095 19.5 3.7 0.00095 19.5 2.6 8.0 5 2 2 7 7 7 2 60s Acidic ribosomal protein SOBP PF15279.1 CDJ67905.1 - 4.1 7.6 23.8 6 7.1 16.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Fil_haemagg_2 PF13332.1 CDJ67906.1 - 0.016 14.9 0.5 0.021 14.5 0.4 1.3 1 0 0 1 1 1 0 Haemagluttinin repeat DUF4512 PF14975.1 CDJ67906.1 - 0.22 12.3 1.4 0.28 12.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Med15 PF09606.5 CDJ67906.1 - 0.39 8.8 12.3 0.42 8.7 8.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SRP-alpha_N PF04086.8 CDJ67906.1 - 1 8.7 5.5 1.1 8.6 3.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Lin-8 PF03353.10 CDJ67906.1 - 2.9 7.1 6.4 3.2 6.9 4.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist KN_motif PF12075.3 CDJ67907.1 - 0.54 10.1 0.0 1.7 8.5 0.0 1.8 1 0 0 1 1 1 0 KN motif PAT1 PF09770.4 CDJ67908.1 - 0.0013 17.0 64.9 0.0013 17.0 45.0 3.0 3 0 0 3 3 3 1 Topoisomerase II-associated protein PAT1 PAT1 PF09770.4 CDJ67909.1 - 2.1e-06 26.3 64.4 2.1e-06 26.3 44.6 2.0 1 1 0 2 2 2 1 Topoisomerase II-associated protein PAT1 MRJP PF03022.11 CDJ67909.1 - 0.053 12.7 2.5 0.082 12.1 1.8 1.3 1 0 0 1 1 1 0 Major royal jelly protein Helicase_C PF00271.26 CDJ67910.1 - 2.9e-11 43.0 0.0 2.9e-11 43.0 0.0 4.5 5 0 0 5 5 5 1 Helicase conserved C-terminal domain AAA PF00004.24 CDJ67910.1 - 0.07 13.3 1.1 6.7 6.9 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Med15 PF09606.5 CDJ67911.1 - 0.021 13.0 35.8 0.024 12.8 24.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3551 PF12071.3 CDJ67911.1 - 0.033 13.7 4.9 0.075 12.6 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3551) Phage_sheath_1 PF04984.9 CDJ67911.1 - 0.34 9.3 8.8 0.77 8.1 6.1 1.5 1 1 0 1 1 1 0 Phage tail sheath protein DUF1183 PF06682.7 CDJ67911.1 - 0.4 10.2 6.1 0.46 10.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF1675 PF07897.6 CDJ67911.1 - 0.53 10.0 8.3 0.6 9.9 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4207 PF13904.1 CDJ67911.1 - 0.56 9.5 16.0 0.75 9.1 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Serinc PF03348.10 CDJ67911.1 - 0.64 8.6 5.9 0.74 8.4 4.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM60A PF15396.1 CDJ67911.1 - 2.1 8.0 5.9 2.5 7.7 4.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A GET2 PF08690.5 CDJ67911.1 - 3.9 6.6 7.0 4.4 6.4 4.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PAT1 PF09770.4 CDJ67911.1 - 7.9 4.5 32.0 9.7 4.2 22.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Surface_antigen PF11054.3 CDJ67912.1 - 4.4e-104 347.3 3.1 5.1e-104 347.1 2.2 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen SecY PF00344.15 CDJ67913.1 - 6.9e-97 324.4 16.7 8.5e-97 324.1 11.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CDJ67913.1 - 5.9e-18 64.0 0.0 1.9e-17 62.4 0.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Chorion_2 PF03964.10 CDJ67913.1 - 0.15 12.5 0.2 0.15 12.5 0.2 2.0 2 0 0 2 2 2 0 Chorion family 2 14-3-3 PF00244.15 CDJ67914.1 - 2.8e-16 59.3 6.9 7.3e-15 54.6 2.8 4.1 4 1 0 4 4 4 2 14-3-3 protein Dev_Cell_Death PF10539.4 CDJ67914.1 - 0.14 11.7 1.3 0.23 11.0 0.3 1.9 2 0 0 2 2 2 0 Development and cell death domain RAP1 PF07218.6 CDJ67914.1 - 0.4 8.7 2.9 0.52 8.3 2.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MecA_N PF05223.6 CDJ67914.1 - 0.58 10.2 5.2 0.52 10.3 0.2 2.8 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain PTPlike_phytase PF14566.1 CDJ67914.1 - 8.9 6.3 8.9 0.39 10.7 0.9 2.3 2 1 0 2 2 2 0 Inositol hexakisphosphate PDEase_I PF00233.14 CDJ67915.1 - 4.4e-27 95.3 0.0 4.4e-27 95.3 0.0 3.7 2 1 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Utp14 PF04615.8 CDJ67916.1 - 0.01 14.0 68.5 0.011 13.9 47.5 1.0 1 0 0 1 1 1 1 Utp14 protein PAT1 PF09770.4 CDJ67916.1 - 0.27 9.4 136.4 0.3 9.2 94.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAR_2 PF10455.4 CDJ67917.1 - 0.076 11.9 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking WD40 PF00400.27 CDJ67918.1 - 4.7e-35 118.2 0.1 3.5e-07 29.8 0.2 9.0 7 1 0 7 7 7 7 WD domain, G-beta repeat Spt20 PF12090.3 CDJ67918.1 - 0.02 14.2 0.2 0.02 14.2 0.1 7.6 6 1 0 6 6 6 0 Spt20 family 60KD_IMP PF02096.15 CDJ67918.1 - 0.033 13.8 0.3 0.033 13.8 0.2 6.8 7 0 0 7 7 7 0 60Kd inner membrane protein TraV PF09676.5 CDJ67919.1 - 0.026 15.2 5.1 0.026 15.2 3.5 2.0 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Afi1 PF07792.7 CDJ67919.1 - 0.29 11.1 8.1 0.34 10.9 5.6 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking VGLL4 PF15245.1 CDJ67919.1 - 0.45 10.3 10.8 0.49 10.1 7.5 1.1 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 APC_CDC26 PF10471.4 CDJ67919.1 - 0.6 10.8 24.3 2.2 9.0 5.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF4055 PF13264.1 CDJ67919.1 - 0.89 9.6 10.8 1.3 9.1 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) PHD_3 PF13922.1 CDJ67919.1 - 2.5 8.4 19.0 3.9 7.7 4.2 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF45 PF01863.12 CDJ67919.1 - 3.5 7.3 8.0 4.1 7.1 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 CDK2AP PF09806.4 CDJ67919.1 - 5.8 7.0 14.0 7.5 6.7 9.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4175 PF13779.1 CDJ67919.1 - 8.5 3.9 27.2 10 3.6 18.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Herpes_LMP1 PF05297.6 CDJ67920.1 - 0.12 11.3 4.6 0.15 10.9 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3070 PF11270.3 CDJ67920.1 - 2.9 7.7 7.5 52 3.7 0.6 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF3070) DUF3292 PF11696.3 CDJ67921.1 - 0.045 11.6 4.8 0.051 11.4 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF4557 PF15101.1 CDJ67921.1 - 0.17 11.6 4.8 0.19 11.5 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MDFI PF15316.1 CDJ67921.1 - 0.42 10.5 6.2 0.49 10.3 4.3 1.1 1 0 0 1 1 1 0 MyoD family inhibitor CDK2AP PF09806.4 CDJ67921.1 - 5 7.3 18.5 6.8 6.8 12.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Cytochrome-c551 PF10643.4 CDJ67921.1 - 5.7 6.1 6.8 6.2 6.0 4.7 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF605 PF04652.11 CDJ67922.1 - 0.005 16.2 24.1 0.005 16.2 16.7 3.3 2 1 1 3 3 3 1 Vta1 like SRP14 PF02290.10 CDJ67922.1 - 0.3 11.0 0.0 0.3 11.0 0.0 3.3 3 2 2 5 5 5 0 Signal recognition particle 14kD protein NUC130_3NT PF08158.7 CDJ67923.1 - 0.077 13.2 0.3 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 NUC130/3NT domain BP28CT PF08146.7 CDJ67924.1 - 0.035 13.8 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 BP28CT (NUC211) domain DivIC PF04977.10 CDJ67924.1 - 0.16 11.4 4.3 0.32 10.5 3.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Spt5_N PF11942.3 CDJ67924.1 - 0.25 11.9 2.0 0.49 11.0 1.4 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Cyt-b5 PF00173.23 CDJ67925.1 - 1.6e-17 63.0 0.0 2.4e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SR-25 PF10500.4 CDJ67925.1 - 0.015 14.7 1.1 0.015 14.7 0.7 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.8 CDJ67925.1 - 1.9 8.2 4.7 2.7 7.8 3.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 CDJ67925.1 - 2.8 7.0 23.7 5.5 6.1 16.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAM104 PF15434.1 CDJ67925.1 - 7.4 6.8 11.8 3.6 7.8 3.1 2.3 2 0 0 2 2 2 0 Family 104 DSPc PF00782.15 CDJ67926.1 - 6.9e-13 48.3 0.8 3.4e-10 39.6 0.3 2.9 2 1 1 3 3 3 2 Dual specificity phosphatase, catalytic domain Ribosomal_60s PF00428.14 CDJ67926.1 - 0.0018 18.6 17.4 0.0018 18.6 12.1 5.6 4 1 0 4 4 4 2 60s Acidic ribosomal protein Dehydrin PF00257.14 CDJ67926.1 - 0.037 14.3 0.7 0.037 14.3 0.5 4.8 3 2 1 4 4 4 0 Dehydrin Y_phosphatase PF00102.22 CDJ67926.1 - 0.043 13.1 0.1 0.043 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF3169 PF11368.3 CDJ67927.1 - 0.0031 16.7 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF2508 PF10704.4 CDJ67927.1 - 0.022 14.8 1.2 0.022 14.8 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF2065 PF09838.4 CDJ67927.1 - 0.029 14.0 0.2 0.029 14.0 0.1 2.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2065) DUF4446 PF14584.1 CDJ67927.1 - 0.087 12.6 2.1 0.34 10.7 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Shisa PF13908.1 CDJ67927.1 - 0.2 11.8 9.3 1.3 9.1 2.0 2.3 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF243 PF03103.12 CDJ67927.1 - 0.82 9.8 7.5 1.7 8.8 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF243) Nuc_deoxyrib_tr PF05014.10 CDJ67927.1 - 1.6 8.6 4.4 1.1 9.1 0.1 2.6 2 1 1 3 3 3 0 Nucleoside 2-deoxyribosyltransferase Med15 PF09606.5 CDJ67928.1 - 0.0012 17.1 138.4 0.0016 16.7 95.9 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Tetraspannin PF00335.15 CDJ67928.1 - 0.0018 17.5 0.3 0.0018 17.5 0.2 2.1 1 1 0 2 2 2 1 Tetraspanin family SR-25 PF10500.4 CDJ67929.1 - 0.12 11.8 61.6 0.018 14.5 9.3 3.1 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein ETRAMP PF09716.5 CDJ67929.1 - 4.1 7.4 17.6 0.18 11.7 0.4 3.4 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TFIIA PF03153.8 CDJ67929.1 - 6.9 6.4 56.2 9.4 6.0 39.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CDJ67929.1 - 8.5 5.6 48.9 11 5.2 33.9 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CDJ67929.1 - 8.7 4.4 58.9 11 4.1 40.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Catalase PF00199.14 CDJ67931.1 - 9.3e-187 620.3 0.0 9.3e-187 620.3 0.0 1.9 2 0 0 2 2 2 1 Catalase DUF755 PF05501.6 CDJ67931.1 - 0.0001 22.3 33.3 0.0001 22.3 23.1 5.6 5 1 0 5 5 5 1 Domain of unknown function (DUF755) Mem_trans PF03547.13 CDJ67931.1 - 0.0015 16.8 0.2 0.0037 15.6 0.1 1.6 1 0 0 1 1 1 1 Membrane transport protein SPX PF03105.14 CDJ67931.1 - 0.0051 16.6 2.9 0.0051 16.6 2.0 3.5 4 0 0 4 4 4 1 SPX domain SAPS PF04499.10 CDJ67931.1 - 3.5 6.1 16.5 1.8 7.1 7.0 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein YfhO PF09586.5 CDJ67931.1 - 6.4 4.6 7.1 12 3.8 4.9 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CDC45 PF02724.9 CDJ67931.1 - 9.6 4.0 21.0 4.1 5.3 6.0 2.3 2 0 0 2 2 2 0 CDC45-like protein PAT1 PF09770.4 CDJ67932.1 - 0.00025 19.4 60.9 0.00028 19.2 42.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDJ67932.1 - 0.13 12.6 18.3 0.12 12.8 6.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein GAGA_bind PF06217.7 CDJ67932.1 - 0.6 10.0 19.2 0.93 9.3 13.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4386 PF14329.1 CDJ67932.1 - 1.3 8.4 9.5 0.16 11.4 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Tetraspannin PF00335.15 CDJ67932.1 - 2.1 7.5 4.3 4.5 6.4 3.0 1.6 1 1 0 1 1 1 0 Tetraspanin family Cyto_heme_lyase PF01265.12 CDJ67932.1 - 3.4 7.1 19.5 6.2 6.3 13.5 1.6 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Asp-B-Hydro_N PF05279.6 CDJ67932.1 - 5.1 6.8 17.4 8.3 6.1 12.1 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3474 PF11960.3 CDJ67933.1 - 1.4 8.9 6.6 0.9 9.5 3.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) Peptidase_U57 PF05582.7 CDJ67934.1 - 0.6 9.0 6.3 0.63 8.9 4.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_S49_N PF08496.5 CDJ67934.1 - 0.73 9.6 7.8 0.32 10.7 1.4 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Band_3_cyto PF07565.8 CDJ67934.1 - 2.2 7.7 6.6 2.7 7.4 4.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain U1snRNP70_N PF12220.3 CDJ67934.1 - 4 7.8 17.0 5.3 7.4 1.3 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pkinase PF00069.20 CDJ67936.1 - 3.7e-21 75.4 2.6 1.1e-10 41.0 0.0 3.7 2 1 2 4 4 4 2 Protein kinase domain Apt1 PF10351.4 CDJ67936.1 - 8.1e-05 21.6 2.8 8.1e-05 21.6 1.9 2.9 2 1 0 2 2 2 1 Golgi-body localisation protein domain Ribosomal_60s PF00428.14 CDJ67936.1 - 0.02 15.2 0.8 0.02 15.2 0.6 6.4 4 2 2 6 6 6 0 60s Acidic ribosomal protein Ycf1 PF05758.7 CDJ67936.1 - 0.17 9.5 9.6 0.0051 14.6 1.9 1.7 2 0 0 2 2 2 0 Ycf1 DUF4446 PF14584.1 CDJ67936.1 - 0.7 9.7 6.7 4.2 7.1 5.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Plasmodium_Vir PF05795.6 CDJ67936.1 - 0.71 9.0 16.4 1.3 8.1 0.3 3.1 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Zip PF02535.17 CDJ67936.1 - 2.2 7.2 12.9 1.4 7.8 0.4 3.3 3 0 0 3 3 3 0 ZIP Zinc transporter SprA-related PF12118.3 CDJ67937.1 - 0.0018 17.6 9.9 0.0024 17.2 6.8 1.2 1 0 0 1 1 1 1 SprA-related family Metallophos PF00149.23 CDJ67937.1 - 0.047 13.0 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Spt20 PF12090.3 CDJ67937.1 - 0.23 10.8 4.4 0.27 10.5 2.9 1.3 1 1 0 1 1 1 0 Spt20 family Macoilin PF09726.4 CDJ67937.1 - 0.29 9.3 11.4 0.38 8.9 7.9 1.2 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 CDJ67937.1 - 1.7 6.6 19.7 2.1 6.3 13.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF605 PF04652.11 CDJ67937.1 - 3.5 6.9 16.5 4.9 6.4 11.4 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 CDJ67937.1 - 3.8 7.3 9.9 4.4 7.0 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KAR9 PF08580.5 CDJ67937.1 - 10 4.2 16.0 12 4.0 11.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 WW PF00397.21 CDJ67938.1 - 2.1e-06 27.4 2.2 2.1e-06 27.4 1.5 1.9 2 0 0 2 2 2 1 WW domain Macoilin PF09726.4 CDJ67939.1 - 2.8 6.1 18.4 3 6.0 12.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Retrotrans_gag PF03732.12 CDJ67940.1 - 0.0076 16.2 0.0 0.032 14.3 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Med15 PF09606.5 CDJ67942.1 - 0.083 11.0 21.2 0.099 10.8 14.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sporozoite_P67 PF05642.6 CDJ67942.1 - 0.24 9.2 4.4 0.26 9.1 3.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF677 PF05055.7 CDJ67942.1 - 0.31 9.6 2.8 0.35 9.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF4647 PF15504.1 CDJ67942.1 - 0.37 9.6 5.7 0.38 9.5 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) PLRV_ORF5 PF01690.12 CDJ67942.1 - 0.94 8.5 5.2 1.1 8.3 3.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein NST1 PF13945.1 CDJ67942.1 - 1.3 9.0 8.2 1.5 8.8 5.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Peptidase_S64 PF08192.6 CDJ67942.1 - 1.4 7.2 7.9 1.4 7.1 5.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Draxin PF15550.1 CDJ67942.1 - 1.9 8.0 6.7 2.3 7.8 4.7 1.2 1 0 0 1 1 1 0 Draxin HGTP_anticodon2 PF12745.2 CDJ67942.1 - 3.1 6.8 7.2 3.8 6.5 5.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Miff PF05644.6 CDJ67942.1 - 3.8 7.0 8.0 4.5 6.8 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Dishevelled PF02377.10 CDJ67942.1 - 5.8 7.1 11.3 9 6.5 7.8 1.4 1 0 0 1 1 1 0 Dishevelled specific domain DUF966 PF06136.8 CDJ67942.1 - 6.3 6.1 8.7 6.8 6.0 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF935 PF06074.7 CDJ67942.1 - 6.8 5.2 15.3 7.5 5.1 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Pol_alpha_B_N PF08418.5 CDJ67942.1 - 7.5 6.0 8.8 9 5.7 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CDK5_activator PF03261.10 CDJ67942.1 - 7.7 5.7 7.3 9.1 5.5 5.0 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DNA_pol_viral_N PF00242.12 CDJ67942.1 - 8.3 5.3 8.2 8.8 5.2 5.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain TFIIA PF03153.8 CDJ67942.1 - 9.5 6.0 15.5 13 5.5 10.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CDJ67942.1 - 9.8 4.3 14.3 11 4.1 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 CDJ67943.1 - 0.0033 16.9 29.9 0.07 12.5 4.5 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.2 CDJ67943.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 1 1 2 2 2 0 SpoIIIAH-like protein Secretin_N_2 PF07655.8 CDJ67943.1 - 2.6 8.5 14.2 2.1 8.8 4.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4614 PF15391.1 CDJ67943.1 - 5.3 6.7 11.1 0.43 10.3 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Urm1 PF09138.6 CDJ67945.1 - 2e-17 63.0 0.0 6.2e-17 61.5 0.0 1.7 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CDJ67945.1 - 0.047 14.1 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 ThiS family LMBR1 PF04791.11 CDJ67946.1 - 1.4e-12 47.0 0.3 1.4e-12 47.0 0.2 1.6 2 0 0 2 2 2 1 LMBR1-like membrane protein SR-25 PF10500.4 CDJ67946.1 - 0.011 15.1 7.3 0.011 15.1 5.0 4.3 4 1 0 4 4 4 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDJ67946.1 - 4.8 7.6 17.7 2.2 8.7 1.0 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein 2HCT PF03390.10 CDJ67947.1 - 0.41 8.9 6.2 1.8 6.8 0.3 2.0 1 1 1 2 2 2 0 2-hydroxycarboxylate transporter family PAT1 PF09770.4 CDJ67947.1 - 3.8 5.6 67.7 4.5 5.3 46.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PARG_cat PF05028.9 CDJ67948.1 - 4.4e-08 32.7 0.1 6.6e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) OmpH PF03938.9 CDJ67948.1 - 0.00026 20.9 0.0 0.00076 19.4 0.0 1.8 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) RskA PF10099.4 CDJ67948.1 - 0.016 14.9 15.5 1.9 8.2 9.0 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA SR-25 PF10500.4 CDJ67948.1 - 0.6 9.5 6.1 1.1 8.7 4.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_1 PF00078.22 CDJ67949.1 - 1.4e-33 116.0 0.0 2.3e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ArsC PF03960.10 CDJ67949.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 ArsC family MIF4G_like PF09088.6 CDJ67949.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 MIF4G like PEPCK_ATP PF01293.15 CDJ67951.1 - 5.7e-37 127.3 3.3 9.6e-34 116.7 2.3 2.7 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CDJ67951.1 - 0.0051 16.6 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.1 CDJ67951.1 - 0.0098 14.4 0.0 0.011 14.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDJ67951.1 - 0.012 15.6 0.2 0.013 15.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CDJ67951.1 - 0.016 14.7 0.2 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CDJ67951.1 - 0.033 13.6 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDJ67951.1 - 0.038 14.1 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CDJ67951.1 - 0.059 13.6 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 CDJ67951.1 - 0.061 13.0 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 CDJ67951.1 - 0.067 12.3 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 CDJ67951.1 - 0.15 12.3 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF243 PF03103.12 CDJ67954.1 - 0.00032 20.7 3.8 0.00049 20.1 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF243) Spt20 PF12090.3 CDJ67954.1 - 0.017 14.4 2.8 0.017 14.5 1.9 1.1 1 0 0 1 1 1 0 Spt20 family PHD_3 PF13922.1 CDJ67954.1 - 0.31 11.3 3.9 0.51 10.6 2.7 1.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Herpes_TAF50 PF03326.8 CDJ67954.1 - 1 8.2 16.6 1.2 7.9 11.5 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Suf PF05843.9 CDJ67954.1 - 3.4 7.3 6.7 3.7 7.2 4.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ67954.1 - 4.9 6.9 11.5 5.1 6.8 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex16 PF08610.5 CDJ67954.1 - 9.6 5.0 9.2 10 4.9 6.1 1.3 1 1 1 2 2 2 0 Peroxisomal membrane protein (Pex16) Ndc80_HEC PF03801.8 CDJ67956.1 - 2.1e-32 111.7 0.0 2.1e-32 111.7 0.0 2.9 3 0 0 3 3 3 1 HEC/Ndc80p family Mnd1 PF03962.10 CDJ67956.1 - 6e-05 22.7 8.3 6e-05 22.7 5.7 4.6 2 2 2 4 4 4 1 Mnd1 family GAS PF13851.1 CDJ67956.1 - 0.00041 19.5 6.2 0.00041 19.5 4.3 3.9 2 2 1 3 3 3 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 CDJ67956.1 - 0.0023 16.6 3.5 0.0023 16.6 2.4 4.1 2 2 2 4 4 4 1 Spc7 kinetochore protein DUF2576 PF10845.3 CDJ67956.1 - 0.17 11.0 1.3 0.42 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Reo_sigmaC PF04582.7 CDJ67956.1 - 6.9 5.7 21.1 0.095 11.8 2.6 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CDJ67956.1 - 9.6 4.5 49.0 0.88 7.9 9.3 2.3 2 0 0 2 2 2 0 AAA domain ADIP PF11559.3 CDJ67956.1 - 9.8 6.0 90.6 0.028 14.3 1.9 5.0 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding Shadoo PF14999.1 CDJ67958.1 - 0.00099 18.9 0.4 0.001 18.9 0.3 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective RskA PF10099.4 CDJ67958.1 - 0.054 13.2 0.9 0.057 13.1 0.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Cyclin_C PF02984.14 CDJ67958.1 - 0.14 12.1 1.4 0.16 11.9 1.0 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain APC_CDC26 PF10471.4 CDJ67958.1 - 0.4 11.4 5.1 0.62 10.8 3.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Isy1 PF06246.7 CDJ67959.1 - 0.0032 16.9 13.7 0.0033 16.8 9.5 1.1 1 0 0 1 1 1 1 Isy1-like splicing family DDHD PF02862.12 CDJ67959.1 - 0.11 12.3 15.1 0.11 12.3 10.4 1.0 1 0 0 1 1 1 0 DDHD domain DUF2514 PF10721.4 CDJ67959.1 - 0.18 11.4 26.3 0.22 11.2 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Zip PF02535.17 CDJ67959.1 - 0.2 10.6 5.2 0.21 10.5 3.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Gly_rich PF12810.2 CDJ67959.1 - 0.22 11.0 4.6 0.26 10.8 3.2 1.0 1 0 0 1 1 1 0 Glycine rich protein DUF4557 PF15101.1 CDJ67959.1 - 0.24 11.2 29.2 0.23 11.2 20.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Band_3_cyto PF07565.8 CDJ67959.1 - 0.24 10.8 18.6 0.27 10.7 12.9 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDJ67959.1 - 0.27 9.4 44.1 0.26 9.5 30.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Paf1 PF03985.8 CDJ67959.1 - 0.32 9.6 22.9 0.33 9.6 15.8 1.0 1 0 0 1 1 1 0 Paf1 GAGA_bind PF06217.7 CDJ67959.1 - 0.35 10.7 15.9 0.34 10.8 11.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Host_attach PF10116.4 CDJ67959.1 - 0.42 10.8 13.7 0.55 10.4 9.5 1.1 1 0 0 1 1 1 0 Protein required for attachment to host cells DHHW PF14286.1 CDJ67959.1 - 0.47 9.7 12.1 0.53 9.5 8.4 1.1 1 0 0 1 1 1 0 DHHW protein FLO_LFY PF01698.11 CDJ67959.1 - 0.48 9.2 17.2 0.47 9.2 11.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Baculo_PP31 PF05311.6 CDJ67959.1 - 0.48 9.6 16.3 0.49 9.6 11.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CPSF100_C PF13299.1 CDJ67959.1 - 0.49 10.5 13.8 0.5 10.5 9.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Raftlin PF15250.1 CDJ67959.1 - 0.51 8.7 14.9 0.49 8.8 10.3 1.0 1 0 0 1 1 1 0 Raftlin NARP1 PF12569.3 CDJ67959.1 - 0.54 8.9 16.8 0.58 8.8 11.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Folate_carrier PF01770.13 CDJ67959.1 - 0.57 8.6 9.1 0.53 8.7 6.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier SeqA PF03925.8 CDJ67959.1 - 0.6 9.7 13.2 0.65 9.6 9.1 1.1 1 0 0 1 1 1 0 SeqA protein OATP PF03137.15 CDJ67959.1 - 0.66 7.9 11.3 0.66 7.9 7.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2201_N PF13203.1 CDJ67959.1 - 0.69 9.0 17.3 0.69 9.0 12.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Sec62 PF03839.11 CDJ67959.1 - 0.72 9.2 10.0 0.68 9.2 6.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.5 CDJ67959.1 - 0.74 9.6 15.8 0.82 9.4 11.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.7 CDJ67959.1 - 0.77 8.9 16.2 0.78 8.8 11.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger TraH_2 PF06871.6 CDJ67959.1 - 0.92 8.9 6.2 0.99 8.8 4.3 1.1 1 0 0 1 1 1 0 TraH_2 CDC45 PF02724.9 CDJ67959.1 - 1.1 7.1 18.9 1.2 7.0 13.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Dala_Dala_lig_N PF01820.16 CDJ67959.1 - 1.4 9.2 9.0 1.8 8.8 6.2 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Ctr PF04145.10 CDJ67959.1 - 1.4 8.9 11.0 1.6 8.8 7.6 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S15 PF02129.13 CDJ67959.1 - 1.6 8.1 15.0 1.7 8.0 10.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ycf1 PF05758.7 CDJ67959.1 - 1.9 6.1 17.8 1.8 6.1 12.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF853 PF05872.7 CDJ67959.1 - 2.5 6.3 16.8 2.6 6.3 11.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AIF_C PF14721.1 CDJ67959.1 - 2.7 8.2 15.9 3.3 7.9 11.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex16 PF08610.5 CDJ67959.1 - 2.8 6.8 17.1 2.8 6.8 11.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SAGA-Tad1 PF12767.2 CDJ67959.1 - 2.8 7.5 21.6 2.7 7.5 15.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2126 PF09899.4 CDJ67959.1 - 3 5.7 13.1 2.8 5.8 9.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) R_equi_Vir PF05526.6 CDJ67959.1 - 3 7.4 7.6 3.4 7.2 5.3 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein YABBY PF04690.8 CDJ67959.1 - 3 8.0 12.3 3.2 7.9 8.6 1.1 1 0 0 1 1 1 0 YABBY protein AUX_IAA PF02309.11 CDJ67959.1 - 3.1 7.5 16.1 3.2 7.4 11.1 1.0 1 0 0 1 1 1 0 AUX/IAA family GPCR_chapero_1 PF11904.3 CDJ67959.1 - 3.2 6.8 15.0 3.1 6.8 10.4 1.0 1 0 0 1 1 1 0 GPCR-chaperone Pal1 PF08316.6 CDJ67959.1 - 3.4 8.1 10.0 3.7 8.0 6.9 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein FAM91_C PF14648.1 CDJ67959.1 - 3.4 6.4 8.0 3.6 6.3 5.5 1.0 1 0 0 1 1 1 0 FAM91 C-terminus AAA_23 PF13476.1 CDJ67959.1 - 3.7 7.8 24.4 4.3 7.6 16.9 1.1 1 0 0 1 1 1 0 AAA domain Hom_end_hint PF05203.11 CDJ67959.1 - 3.7 7.2 11.6 4.3 6.9 8.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint MDFI PF15316.1 CDJ67959.1 - 4 7.4 9.0 4.4 7.2 6.2 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Herpes_DNAp_acc PF04929.7 CDJ67959.1 - 4.5 6.1 14.5 4.5 6.1 10.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor UPF0560 PF10577.4 CDJ67959.1 - 4.6 5.3 28.4 5.1 5.2 19.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RR_TM4-6 PF06459.7 CDJ67959.1 - 5.5 6.7 18.8 6 6.6 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.7 CDJ67959.1 - 5.6 5.6 10.1 5.8 5.5 7.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.12 CDJ67959.1 - 6 5.5 11.5 6 5.5 8.0 1.0 1 0 0 1 1 1 0 Presenilin Serinc PF03348.10 CDJ67959.1 - 6.1 5.4 17.9 6.7 5.3 12.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.1 CDJ67959.1 - 6.8 4.7 10.8 6.6 4.7 7.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mem_trans PF03547.13 CDJ67959.1 - 7.1 4.8 8.6 6.9 4.8 5.9 1.0 1 0 0 1 1 1 0 Membrane transport protein Kei1 PF08552.6 CDJ67959.1 - 7.4 6.1 13.7 8.4 6.0 9.5 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 GOLD_2 PF13897.1 CDJ67959.1 - 7.9 6.7 8.6 10 6.3 6.0 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF1800 PF08811.6 CDJ67959.1 - 8.7 5.1 23.5 8 5.2 16.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) CRF1 PF10380.4 CDJ67959.1 - 8.8 6.6 17.1 12 6.2 11.9 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 DUF4512 PF14975.1 CDJ67959.1 - 9.2 7.1 11.9 11 6.8 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF2347 PF09804.4 CDJ67959.1 - 9.7 5.3 10.2 9.8 5.3 7.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SNF2_N PF00176.18 CDJ67960.1 - 4.1e-19 68.4 0.8 4.5e-19 68.3 0.5 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 CDJ67960.1 - 0.0041 15.9 0.8 0.012 14.4 0.5 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 RPAP3_C PF13877.1 CDJ67960.1 - 0.034 14.0 0.1 0.054 13.4 0.1 1.2 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Innate_immun PF12782.2 CDJ67961.1 - 0.17 11.0 23.6 0.24 10.5 16.3 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Presenilin PF01080.12 CDJ67961.1 - 1 8.1 11.9 1.2 7.8 8.3 1.1 1 0 0 1 1 1 0 Presenilin DUF966 PF06136.8 CDJ67961.1 - 2 7.7 18.7 2.5 7.4 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SelP_N PF04592.9 CDJ67961.1 - 4.3 6.6 41.9 0.92 8.8 10.8 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region ATAD4 PF15321.1 CDJ67961.1 - 8.4 7.4 22.2 13 6.8 6.1 2.4 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF4207 PF13904.1 CDJ67961.1 - 9.9 5.4 37.3 13 5.0 25.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) PC_rep PF01851.17 CDJ67962.1 - 1.1e-12 47.3 16.3 0.00045 20.2 0.6 4.1 4 0 0 4 4 4 3 Proteasome/cyclosome repeat Dynein_IC2 PF11540.3 CDJ67962.1 - 0.065 12.6 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 Peptidase_M1 PF01433.15 CDJ67963.1 - 5.5e-10 38.8 0.0 6.9e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Endonuclease_NS PF01223.18 CDJ67964.1 - 0.00061 19.4 0.0 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclease_NS PF01223.18 CDJ67965.1 - 0.0005 19.7 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease RVT_1 PF00078.22 CDJ67967.1 - 6.4e-19 68.1 0.0 1.3e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBACT PF02134.16 CDJ67968.1 - 1.4e-19 69.3 0.1 4.7e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 CDJ67968.1 - 3.5e-06 27.1 0.1 7.5e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain DUF3338 PF11819.3 CDJ67968.1 - 0.014 14.8 1.8 0.031 13.7 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) Macoilin PF09726.4 CDJ67968.1 - 0.022 13.0 5.3 0.026 12.8 3.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1635 PF07795.6 CDJ67968.1 - 0.024 13.9 5.0 0.036 13.4 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Sec3_C PF09763.4 CDJ67968.1 - 0.086 10.9 3.9 0.096 10.8 2.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF572 PF04502.8 CDJ67968.1 - 0.14 11.3 7.5 0.19 10.8 5.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) POX PF07526.6 CDJ67968.1 - 0.16 12.2 5.1 0.28 11.4 3.5 1.4 1 0 0 1 1 1 0 Associated with HOX CDC45 PF02724.9 CDJ67968.1 - 0.2 9.6 5.6 0.22 9.5 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.4 CDJ67968.1 - 0.28 10.0 11.6 0.36 9.6 8.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2217 PF10265.4 CDJ67968.1 - 0.36 9.5 4.6 0.51 9.0 3.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Bul1_C PF04426.7 CDJ67968.1 - 0.37 9.9 6.3 0.52 9.4 4.4 1.1 1 0 0 1 1 1 0 Bul1 C terminus Inp1 PF12634.2 CDJ67968.1 - 0.69 9.5 6.0 1.2 8.8 4.2 1.4 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 Na_trans_assoc PF06512.8 CDJ67968.1 - 1.2 9.0 8.4 1.7 8.5 5.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2051 PF09738.4 CDJ67968.1 - 1.4 8.1 13.2 1.9 7.6 9.2 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DUF4614 PF15391.1 CDJ67968.1 - 1.6 8.4 14.3 3.1 7.5 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Cwf_Cwc_15 PF04889.7 CDJ67968.1 - 1.6 8.3 11.1 2.5 7.7 7.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AF-4 PF05110.8 CDJ67968.1 - 2.2 6.0 22.1 2.7 5.7 15.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pox_RNA_Pol_19 PF05320.7 CDJ67968.1 - 2.3 7.9 7.7 3.9 7.1 5.3 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Herpes_capsid PF06112.6 CDJ67968.1 - 2.3 8.2 14.9 0.16 12.0 6.6 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein BUD22 PF09073.5 CDJ67968.1 - 3.8 6.4 15.1 4.9 6.1 10.5 1.1 1 0 0 1 1 1 0 BUD22 CAF-1_p150 PF11600.3 CDJ67968.1 - 6.2 6.1 17.7 11 5.3 12.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-CCHC PF00098.18 CDJ67969.1 - 0.0028 17.5 0.6 0.0059 16.4 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Sec63 PF02889.11 CDJ67970.1 - 5e-48 163.9 0.0 7.6e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CDJ67970.1 - 7.9e-35 119.8 6.0 3.8e-18 65.5 0.0 3.7 3 1 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CDJ67970.1 - 5.4e-09 36.1 3.8 0.015 15.1 0.0 4.5 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CDJ67970.1 - 8.3e-09 35.2 3.7 0.00038 20.2 0.0 3.8 4 0 0 4 4 4 2 Helicase conserved C-terminal domain UPF0086 PF01868.11 CDJ67971.1 - 1e-05 25.1 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF87 PF01935.12 CDJ67971.1 - 3.3 7.4 8.6 5.2 6.8 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Utp14 PF04615.8 CDJ67973.1 - 0.21 9.7 80.0 0.27 9.3 55.4 1.0 1 0 0 1 1 1 0 Utp14 protein RAP1 PF07218.6 CDJ67973.1 - 0.36 8.8 15.7 0.84 7.6 10.9 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HpaP PF09483.5 CDJ67974.1 - 0.074 13.0 9.6 0.088 12.7 6.6 1.0 1 0 0 1 1 1 0 Type III secretion protein (HpaP) TraT PF05818.7 CDJ67974.1 - 0.22 10.8 6.8 0.26 10.7 4.7 1.0 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF4349 PF14257.1 CDJ67974.1 - 0.57 9.3 11.2 0.63 9.2 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Histone PF00125.19 CDJ67975.1 - 5.9e-27 93.5 0.0 9.4e-27 92.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CDJ67975.1 - 0.027 14.6 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S SR-25 PF10500.4 CDJ67975.1 - 0.2 11.0 6.4 0.28 10.6 4.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-T PF15511.1 CDJ67975.1 - 0.28 10.4 11.6 3.2 6.8 8.0 2.0 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T YicC_N PF03755.8 CDJ67976.1 - 0.74 9.7 3.5 0.79 9.6 2.4 1.0 1 0 0 1 1 1 0 YicC-like family, N-terminal region DUF3138 PF11336.3 CDJ67976.1 - 7 4.6 12.6 6.7 4.7 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4139 PF13598.1 CDJ67976.1 - 8.3 5.6 9.4 8.6 5.5 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) FlgD PF03963.9 CDJ67977.1 - 0.062 13.3 5.2 8.8 6.4 3.3 2.6 1 1 1 2 2 2 0 Flagellar hook capping protein - N-terminal region Corona_nucleoca PF00937.13 CDJ67977.1 - 0.56 9.1 4.9 0.74 8.7 3.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Cyclin PF08613.6 CDJ67977.1 - 1.2 9.4 4.5 0.44 10.9 0.3 1.9 2 0 0 2 2 2 0 Cyclin DUF1183 PF06682.7 CDJ67977.1 - 1.4 8.4 6.4 1.8 8.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF515 PF04415.7 CDJ67977.1 - 2.5 6.2 7.9 3 5.9 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RAP1 PF07218.6 CDJ67977.1 - 8.9 4.2 13.3 11 3.9 9.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MerC PF03203.9 CDJ67978.1 - 1.2e-07 32.0 11.0 1.2e-07 32.0 7.6 2.3 2 1 0 2 2 2 1 MerC mercury resistance protein Apt1 PF10351.4 CDJ67978.1 - 0.49 9.1 12.1 0.055 12.3 3.8 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain TFIIA PF03153.8 CDJ67978.1 - 9.5 5.9 28.7 6.9 6.4 10.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hydrolase_like PF13242.1 CDJ67979.1 - 7.2e-07 28.8 0.0 2.2e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like PGP_phosphatase PF09419.5 CDJ67979.1 - 0.025 13.9 0.0 0.069 12.5 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase DDHD PF02862.12 CDJ67979.1 - 0.18 11.5 21.4 0.37 10.5 4.7 2.4 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.11 CDJ67979.1 - 0.98 9.2 25.2 0.27 11.0 4.9 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDJ67979.1 - 1.4 6.5 26.8 0.49 8.0 6.4 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Rtf2 PF04641.7 CDJ67979.1 - 4.8 6.3 24.7 2.5 7.2 3.9 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Retrotrans_gag PF03732.12 CDJ67980.1 - 2.7e-06 27.3 0.4 0.22 11.6 0.0 3.5 5 0 0 5 5 5 2 Retrotransposon gag protein Terpene_synth_C PF03936.11 CDJ67980.1 - 0.00053 19.3 2.1 0.14 11.3 0.1 2.4 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain NOB1_Zn_bind PF08772.6 CDJ67980.1 - 0.019 14.7 0.0 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like SSI PF00720.12 CDJ67980.1 - 0.03 14.2 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Subtilisin inhibitor-like Ubiq_cyt_C_chap PF03981.7 CDJ67980.1 - 0.053 13.3 0.3 15 5.4 0.0 2.7 3 0 0 3 3 3 0 Ubiquinol-cytochrome C chaperone DUF2939 PF11159.3 CDJ67980.1 - 0.055 13.6 0.0 26 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) Hemerythrin PF01814.18 CDJ67980.1 - 0.16 12.1 3.0 12 6.0 0.2 3.1 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain TetR_C_6 PF13977.1 CDJ67980.1 - 1.7 8.6 11.0 16 5.5 0.2 4.3 4 0 0 4 4 4 0 Bacterial transcriptional repressor ELO PF01151.13 CDJ67981.1 - 1e-08 34.8 1.4 1.4e-08 34.3 0.3 1.7 1 1 1 2 2 2 1 GNS1/SUR4 family Apt1 PF10351.4 CDJ67984.1 - 0.0066 15.3 1.0 0.0066 15.3 0.7 3.4 3 1 0 3 3 3 1 Golgi-body localisation protein domain DDHD PF02862.12 CDJ67984.1 - 0.0095 15.7 9.8 0.0095 15.7 6.8 3.9 3 2 0 3 3 3 1 DDHD domain SAPS PF04499.10 CDJ67984.1 - 6.9 5.1 44.4 0.61 8.6 6.6 3.1 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein Ribosomal_60s PF00428.14 CDJ67985.1 - 0.00021 21.6 9.9 0.00021 21.6 6.8 9.2 5 2 0 6 6 6 3 60s Acidic ribosomal protein HAT PF02184.11 CDJ67986.1 - 3.9e-07 29.6 2.1 0.01 15.5 0.0 3.4 3 0 0 3 3 3 2 HAT (Half-A-TPR) repeat Spt20 PF12090.3 CDJ67986.1 - 0.0025 17.2 0.7 0.0035 16.7 0.5 1.3 1 0 0 1 1 1 1 Spt20 family U3_assoc_6 PF08640.6 CDJ67986.1 - 0.028 14.1 5.5 0.1 12.3 0.1 3.1 1 1 2 3 3 3 0 U3 small nucleolar RNA-associated protein 6 DUF2946 PF11162.3 CDJ67986.1 - 0.032 14.4 0.4 0.051 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TPR_14 PF13428.1 CDJ67986.1 - 0.032 14.8 0.9 34 5.4 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Activator_LAG-3 PF11498.3 CDJ67986.1 - 0.055 12.2 19.1 0.084 11.6 13.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2844 PF11005.3 CDJ67986.1 - 0.082 12.6 2.0 0.16 11.7 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) G0-G1_switch_2 PF15103.1 CDJ67986.1 - 2.6 8.3 5.3 1 9.6 0.9 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 BAF1_ABF1 PF04684.8 CDJ67986.1 - 4.6 5.9 15.8 7.1 5.3 11.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1631 PF07793.6 CDJ67987.1 - 3.5 5.6 17.2 3.9 5.4 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) LRR_8 PF13855.1 CDJ67989.1 - 4.5e-06 26.3 8.1 0.00031 20.4 3.4 4.8 5 1 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 CDJ67989.1 - 3.5 7.3 50.5 0.025 14.1 2.5 6.6 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) HEV_ORF1 PF02444.11 CDJ67990.1 - 1.4 9.1 15.5 3.3 7.9 10.7 1.7 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) MORN PF02493.15 CDJ67991.1 - 1.6e-12 46.3 14.0 4.7e-06 26.0 0.5 4.5 4 0 0 4 4 4 2 MORN repeat SAM_1 PF00536.25 CDJ67991.1 - 1.6e-06 28.1 0.3 1.6e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CDJ67991.1 - 0.00083 19.1 0.3 0.0016 18.2 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SR-25 PF10500.4 CDJ67991.1 - 0.0016 17.9 1.0 0.0016 17.9 0.7 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 CDJ67991.1 - 0.059 12.5 0.1 0.059 12.5 0.1 1.5 2 0 0 2 2 2 0 Protein kinase domain Spt20 PF12090.3 CDJ67991.1 - 0.21 10.9 3.5 1.1 8.5 0.6 2.2 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.5 CDJ67991.1 - 0.51 8.4 28.4 0.23 9.6 9.3 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dehydrin PF00257.14 CDJ67991.1 - 8.1 6.7 9.5 1.7 8.9 0.2 2.3 2 0 0 2 2 2 0 Dehydrin Glycos_transf_1 PF00534.15 CDJ67992.1 - 5.8e-07 29.0 0.0 2.4e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Sec3_C PF09763.4 CDJ67992.1 - 0.53 8.3 4.5 0.64 8.0 3.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF2051 PF09738.4 CDJ67992.1 - 0.98 8.6 8.1 1.4 8.1 5.6 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Mcm10 PF09332.6 CDJ67992.1 - 2 7.6 8.5 3.7 6.8 5.9 1.3 1 0 0 1 1 1 0 Mcm10 replication factor RAP1 PF07218.6 CDJ67992.1 - 3.1 5.7 8.3 3.9 5.4 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Gp58 PF07902.6 CDJ67994.1 - 0.11 10.6 7.7 0.14 10.3 5.3 1.2 1 0 0 1 1 1 0 gp58-like protein Spc7 PF08317.6 CDJ67994.1 - 2.9 6.4 13.3 6.7 5.2 9.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.1 CDJ67994.1 - 5.6 5.2 9.7 8 4.7 6.7 1.2 1 0 0 1 1 1 0 AAA domain Bax1-I PF01027.15 CDJ67995.1 - 1.1e-29 103.5 35.1 1.3e-29 103.3 24.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Med15 PF09606.5 CDJ67996.1 - 0.0012 17.1 14.9 0.0012 17.1 10.3 4.9 4 2 0 4 4 4 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF912 PF06024.7 CDJ67996.1 - 0.03 14.3 14.0 3.3 7.8 0.2 5.6 5 0 0 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2973 PF11189.3 CDJ67996.1 - 0.071 12.8 0.2 0.071 12.8 0.2 4.8 6 0 0 6 6 6 0 Protein of unknown function (DUF2973) Glt_symporter PF03616.9 CDJ67996.1 - 0.43 9.0 4.4 1.8 6.9 0.1 2.8 3 0 0 3 3 3 0 Sodium/glutamate symporter DUF3899 PF13038.1 CDJ67996.1 - 3.4 7.8 5.5 39 4.4 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) rve PF00665.21 CDJ67998.1 - 1.8e-10 40.9 0.0 3.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RRM_1 PF00076.17 CDJ67999.1 - 9.4e-19 66.8 0.1 1.6e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ67999.1 - 6.4e-13 48.4 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ67999.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoU_methylase PF00588.14 CDJ68001.1 - 4e-09 36.4 0.0 7.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF1042 PF06294.6 CDJ68003.1 - 8e-14 51.5 0.0 8e-14 51.5 0.0 5.1 6 0 0 6 6 6 1 Domain of Unknown Function (DUF1042) FAM60A PF15396.1 CDJ68003.1 - 5.8e-05 22.9 11.5 5.8e-05 22.9 8.0 6.9 7 2 0 7 7 7 1 Protein Family FAM60A CaKB PF03185.10 CDJ68003.1 - 0.31 10.3 7.5 0.95 8.7 3.4 2.4 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit AAA_17 PF13207.1 CDJ68003.1 - 0.31 11.8 0.0 1.6 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Erv26 PF04148.8 CDJ68003.1 - 3.2 7.0 3.7 20 4.4 2.6 2.4 1 1 0 1 1 1 0 Transmembrane adaptor Erv26 Cellulose_synt PF03552.9 CDJ68003.1 - 8.1 4.6 5.9 19 3.3 4.1 1.5 1 0 0 1 1 1 0 Cellulose synthase 7tm_2 PF00002.19 CDJ68004.1 - 0.02 13.9 0.4 0.061 12.3 0.3 1.7 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) HCO3_cotransp PF00955.16 CDJ68004.1 - 0.17 10.4 3.0 0.086 11.4 0.1 1.9 2 0 0 2 2 2 0 HCO3- transporter family DnaJ PF00226.26 CDJ68005.1 - 4.4e-17 61.5 0.0 5.8e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain TAP42 PF04177.7 CDJ68006.1 - 9e-25 87.3 7.9 5e-15 55.3 0.0 3.1 2 1 1 3 3 3 2 TAP42-like family SR-25 PF10500.4 CDJ68006.1 - 0.0066 15.9 9.8 0.0066 15.9 6.8 3.6 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein RskA PF10099.4 CDJ68006.1 - 0.32 10.7 18.7 0.031 14.0 4.4 2.9 3 0 0 3 3 3 0 Anti-sigma-K factor rskA APC_CDC26 PF10471.4 CDJ68006.1 - 9.8 7.0 18.3 0.5 11.1 6.3 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 RskA PF10099.4 CDJ68008.1 - 1.2 8.8 18.9 1.6 8.4 13.1 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA R_equi_Vir PF05526.6 CDJ68008.1 - 4.1 6.9 10.0 4.4 6.8 6.9 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TPPII_N PF12583.3 CDJ68008.1 - 7.2 6.7 16.6 8.5 6.5 11.5 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Spt20 PF12090.3 CDJ68009.1 - 0.0088 15.4 4.7 0.12 11.6 0.5 2.1 2 0 0 2 2 2 2 Spt20 family Suf PF05843.9 CDJ68009.1 - 0.45 10.2 8.4 1.4 8.5 2.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Urb2 PF10441.4 CDJ68009.1 - 2.7 7.5 8.9 8.6 5.8 6.2 1.8 1 1 0 1 1 1 0 Urb2/Npa2 family APC_CDC26 PF10471.4 CDJ68009.1 - 3.6 8.3 25.1 0.31 11.7 2.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 CKAP2_C PF15297.1 CDJ68009.1 - 8.1 5.1 9.2 0.17 10.6 1.1 1.8 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus DUF1183 PF06682.7 CDJ68009.1 - 9.2 5.7 12.8 0.42 10.1 4.6 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1183) QCR10 PF09796.4 CDJ68010.1 - 1.7 8.3 0.0 1.7 8.3 0.0 6.3 5 1 0 5 5 5 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) ABC_membrane PF00664.18 CDJ68011.1 - 1.3e-26 93.6 0.1 1.8e-26 93.2 0.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region AP2 PF00847.15 CDJ68012.1 - 4.2e-08 33.2 1.3 4.2e-08 33.2 0.9 6.6 9 0 0 9 9 9 1 AP2 domain Surface_antigen PF11054.3 CDJ68013.1 - 1.7e-24 86.5 0.0 1.8e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF2296 PF10058.4 CDJ68013.1 - 0.062 13.0 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Retrotrans_gag PF03732.12 CDJ68014.1 - 8.6e-06 25.7 0.0 3.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDJ68014.1 - 6.5e-05 22.6 2.2 6.5e-05 22.6 1.6 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ68014.1 - 0.016 14.9 0.6 0.039 13.6 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 CDJ68015.1 - 4.1e-21 75.2 0.0 7.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDJ68015.1 - 0.0046 16.3 1.1 0.0095 15.3 0.7 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 CDJ68015.1 - 0.026 14.0 0.2 0.094 12.2 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain E1-E2_ATPase PF00122.15 CDJ68017.1 - 3.9e-65 219.1 1.7 1.4e-63 214.0 0.6 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDJ68017.1 - 8.4e-52 175.3 2.7 1.7e-51 174.3 1.8 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDJ68017.1 - 9.1e-32 111.2 0.1 3.3e-30 106.1 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDJ68017.1 - 2.2e-21 75.6 0.0 4.4e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CDJ68017.1 - 4.5e-19 67.6 0.1 1.8e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CDJ68017.1 - 4.8e-13 49.7 1.0 3.1e-12 47.0 0.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDJ68017.1 - 1.3e-05 24.9 0.5 7e-05 22.5 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CDJ68017.1 - 0.079 12.8 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Bap31 PF05529.7 CDJ68018.1 - 0.23 10.9 2.8 3 7.2 0.7 2.5 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF3457 PF11939.3 CDJ68018.1 - 7.8 5.9 9.7 0.17 11.4 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3457) Methyltrans_RNA PF04452.9 CDJ68019.1 - 5.8e-33 113.9 0.0 5.6e-18 64.8 0.0 2.2 2 0 0 2 2 2 2 RNA methyltransferase DUF2893 PF11459.3 CDJ68019.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknwon function (DUF2893) Oligomerisation PF02410.10 CDJ68020.1 - 7.5e-10 38.7 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Oligomerisation domain Apt1 PF10351.4 CDJ68020.1 - 9.9 4.8 10.4 21 3.8 7.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C3HC4 PF00097.20 CDJ68021.1 - 0.0024 17.5 10.8 0.0024 17.5 7.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ68021.1 - 0.0028 17.3 11.2 0.0028 17.3 7.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDJ68021.1 - 0.0044 17.0 8.5 0.0044 17.0 5.9 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EcsC PF12787.2 CDJ68021.1 - 2.1 7.6 26.7 0.015 14.7 10.9 2.5 2 0 0 2 2 2 0 EcsC protein family zf-RING_2 PF13639.1 CDJ68021.1 - 2.5 7.9 21.4 32 4.4 14.8 2.4 1 1 1 2 2 2 0 Ring finger domain RAP PF08373.5 CDJ68022.1 - 1.3e-15 56.9 0.0 2.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 RAP domain DUF3650 PF12368.3 CDJ68022.1 - 0.075 12.5 0.3 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) Retrotrans_gag PF03732.12 CDJ68023.1 - 8.1e-12 45.0 0.2 1.2e-05 25.2 0.0 2.6 3 0 0 3 3 3 2 Retrotransposon gag protein NDUF_B4 PF07225.7 CDJ68023.1 - 0.02 14.6 0.3 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) TRCF PF03461.10 CDJ68023.1 - 0.18 11.7 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 TRCF domain Gemini_AC4_5 PF04807.7 CDJ68023.1 - 0.33 10.4 1.8 6.6 6.2 0.0 3.5 4 0 0 4 4 4 0 Geminivirus AC4/5 conserved region GAGA_bind PF06217.7 CDJ68024.1 - 1.3 8.9 25.1 0.21 11.5 6.6 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family zf-DHHC PF01529.15 CDJ68024.1 - 2.3 7.5 11.3 1.1 8.5 3.7 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase FAM60A PF15396.1 CDJ68024.1 - 3 7.5 15.6 0.86 9.3 4.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A FLO_LFY PF01698.11 CDJ68024.1 - 3.2 6.5 21.2 0.11 11.3 5.0 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Ndc1_Nup PF09531.5 CDJ68024.1 - 9.2 4.5 18.2 14 3.9 12.3 1.5 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.9 CDJ68026.1 - 0.00065 19.5 33.2 0.014 15.1 3.5 3.6 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) LMBR1 PF04791.11 CDJ68026.1 - 0.056 12.0 0.2 3.8 5.9 0.8 2.6 2 1 0 2 2 2 0 LMBR1-like membrane protein Plasmodium_Vir PF05795.6 CDJ68026.1 - 0.41 9.8 6.1 4.9 6.2 0.2 2.9 3 0 0 3 3 3 0 Plasmodium vivax Vir protein 7tm_1 PF00001.16 CDJ68026.1 - 0.75 8.8 7.1 1.4 7.9 0.0 3.5 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) Neur_chan_memb PF02932.11 CDJ68026.1 - 4.4 7.1 23.0 0.15 11.9 1.2 3.8 3 1 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region UPF0233 PF06781.7 CDJ68026.1 - 5.7 6.6 8.7 54 3.5 0.0 4.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) PIG-U PF06728.8 CDJ68026.1 - 8.7 5.0 12.1 2.7 6.7 0.4 3.1 3 0 0 3 3 3 0 GPI transamidase subunit PIG-U Bax1-I PF01027.15 CDJ68027.1 - 0.0019 17.8 0.1 0.0021 17.7 0.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4013 PF13197.1 CDJ68027.1 - 0.031 13.6 0.0 0.035 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) Ribosomal_L4 PF00573.17 CDJ68030.1 - 0.027 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Ribosomal_S15 PF00312.17 CDJ68031.1 - 5.3e-09 35.7 1.3 5.3e-09 35.7 0.9 1.8 2 1 0 2 2 2 1 Ribosomal protein S15 DUF2514 PF10721.4 CDJ68031.1 - 0.12 12.1 5.8 0.16 11.6 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Ribosomal_L6e PF01159.14 CDJ68031.1 - 0.36 11.0 3.4 0.28 11.4 1.3 1.6 2 0 0 2 2 2 0 Ribosomal protein L6e DUF2722 PF10846.3 CDJ68032.1 - 0.1 11.5 8.9 0.29 10.1 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3357 PF11837.3 CDJ68032.1 - 0.23 11.3 6.3 0.49 10.2 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) PBP1_TM PF14812.1 CDJ68032.1 - 0.28 11.5 6.8 3.8 7.8 1.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HA2 PF04408.18 CDJ68032.1 - 0.51 10.3 3.4 0.22 11.5 0.2 1.9 2 1 0 2 2 2 0 Helicase associated domain (HA2) Pex14_N PF04695.8 CDJ68032.1 - 0.56 10.2 8.6 1.7 8.7 2.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 7tm_1 PF00001.16 CDJ68032.1 - 3.9 6.5 5.1 6.2 5.8 0.0 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) RAB3GAP2_N PF14655.1 CDJ68032.1 - 4.6 6.1 9.2 4.4 6.1 1.8 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF457 PF04307.9 CDJ68032.1 - 4.8 6.4 5.4 0.45 9.8 0.6 1.5 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) MMR_HSR1 PF01926.18 CDJ68033.1 - 1.1e-12 47.9 0.0 5e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 CDJ68033.1 - 1.2e-05 25.0 11.4 0.0038 16.8 0.5 3.3 3 1 0 3 3 3 2 GTP1/OBG FeoB_N PF02421.13 CDJ68033.1 - 0.00022 20.5 0.0 0.013 14.7 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CDJ68033.1 - 0.0034 16.8 0.9 0.017 14.5 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CDJ68033.1 - 2.1 7.8 4.1 10 5.5 2.0 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 CDJ68033.1 - 6.2 7.1 13.8 4.3e+02 1.1 9.6 2.7 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 CDJ68033.1 - 9.5 6.4 19.1 0.45 10.7 7.9 2.6 3 0 0 3 3 3 0 AAA domain Ribosomal_L24e PF01246.15 CDJ68034.1 - 1.3e-27 95.3 3.7 3e-27 94.2 2.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 CDJ68034.1 - 0.003 17.1 3.0 0.003 17.1 2.1 1.9 2 1 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif DDHD PF02862.12 CDJ68034.1 - 0.88 9.3 11.5 1 9.1 8.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF3584 PF12128.3 CDJ68034.1 - 1.1 6.4 27.9 1.3 6.2 19.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) EF-1_beta_acid PF10587.4 CDJ68034.1 - 1.6 8.9 10.5 0.17 12.0 2.5 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Lumazine_bd PF12870.2 CDJ68034.1 - 3 7.9 7.9 1.7 8.6 3.7 1.9 1 1 1 2 2 2 0 Lumazine-binding domain GOLD_2 PF13897.1 CDJ68034.1 - 3.5 7.8 9.1 43 4.3 0.0 2.8 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Spore_coat_CotO PF14153.1 CDJ68034.1 - 6.5 6.1 22.0 12 5.2 15.2 1.5 1 1 0 1 1 1 0 Spore coat protein CotO Sld5 PF05916.6 CDJ68035.1 - 0.0052 17.0 0.0 0.0083 16.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF4205 PF13898.1 CDJ68036.1 - 1.3e-48 165.5 0.0 3.1e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) DUF457 PF04307.9 CDJ68036.1 - 0.063 12.5 0.2 0.063 12.5 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Spt20 PF12090.3 CDJ68036.1 - 1 8.6 11.8 8.4 5.7 2.0 3.2 3 0 0 3 3 3 0 Spt20 family WD40 PF00400.27 CDJ68037.1 - 1.3e-08 34.3 13.0 2.3e-07 30.4 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat AMA-1 PF02430.10 CDJ68038.1 - 9e-64 216.0 0.2 1.3e-63 215.5 0.2 1.2 1 0 0 1 1 1 1 Apical membrane antigen 1 Lamp PF01299.12 CDJ68038.1 - 0.047 12.8 0.7 0.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) AAA_17 PF13207.1 CDJ68039.1 - 0.057 14.2 3.2 15 6.4 0.0 3.5 3 1 0 3 3 3 0 AAA domain WD40 PF00400.27 CDJ68040.1 - 5.9e-06 25.9 0.3 0.067 13.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat HEAT PF02985.17 CDJ68041.1 - 0.004 17.1 13.9 0.07 13.2 0.2 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CDJ68041.1 - 0.18 12.1 14.5 1.4 9.2 4.8 3.4 2 1 1 3 3 3 0 HEAT repeats RIX1 PF08167.7 CDJ68042.1 - 0.005 16.5 0.1 0.015 15.0 0.1 1.8 1 1 0 1 1 1 1 rRNA processing/ribosome biogenesis Trichoplein PF13868.1 CDJ68043.1 - 2.1e-06 26.3 141.3 2.1e-06 26.3 97.9 2.1 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin Coatomer_WDAD PF04053.9 CDJ68044.1 - 0.0068 15.2 0.5 0.0086 14.9 0.4 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Histone PF00125.19 CDJ68048.1 - 2e-21 75.9 0.1 2.6e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CDJ68048.1 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hph PF13694.1 CDJ68049.1 - 4 7.4 9.7 5.1 7.0 6.6 1.4 1 1 0 1 1 1 0 Sec63/Sec62 complex-interacting family eIF-3c_N PF05470.7 CDJ68049.1 - 6 4.8 7.9 6.9 4.6 5.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mito_carr PF00153.22 CDJ68050.1 - 8.9e-60 198.4 12.8 1.3e-25 88.9 0.0 5.0 5 0 0 5 5 5 4 Mitochondrial carrier protein zf-C2H2_2 PF12756.2 CDJ68051.1 - 1.7e-17 63.3 1.1 1.7e-17 63.3 0.8 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CDJ68051.1 - 0.062 13.4 7.3 2.5 8.3 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AMP-binding PF00501.23 CDJ68052.1 - 6.7e-24 84.0 0.3 3.4e-22 78.4 0.0 3.1 1 1 0 2 2 2 2 AMP-binding enzyme DALR_1 PF05746.10 CDJ68053.1 - 2.3e-12 46.9 0.0 2.3e-12 46.9 0.0 4.1 3 1 0 3 3 2 1 DALR anticodon binding domain SR-25 PF10500.4 CDJ68053.1 - 0.00019 20.9 5.9 0.00019 20.9 4.1 5.7 5 2 0 5 5 4 1 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDJ68053.1 - 0.15 11.7 49.8 0.24 11.0 6.0 3.9 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) CDC45 PF02724.9 CDJ68053.1 - 0.37 8.7 28.6 0.095 10.7 5.5 3.4 3 0 0 3 3 3 0 CDC45-like protein Spore_coat_CotO PF14153.1 CDJ68053.1 - 1 8.8 49.9 0.9 8.9 13.3 3.7 4 0 0 4 4 4 0 Spore coat protein CotO Herpes_UL87 PF03043.9 CDJ68053.1 - 2 6.7 23.4 0.2 10.0 1.8 3.0 2 2 1 3 3 3 0 Herpesvirus UL87 family SAPS PF04499.10 CDJ68053.1 - 2.2 6.8 26.8 0.36 9.4 9.2 2.6 2 2 0 2 2 2 0 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.3 CDJ68053.1 - 3.4 7.0 77.6 0.33 10.3 12.0 4.3 4 0 0 4 4 4 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 CDJ68053.1 - 6.4 6.5 37.6 0.32 10.8 2.2 3.8 4 0 0 4 4 4 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 CDJ68053.1 - 7 5.9 40.0 6.8 5.9 11.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Med15 PF09606.5 CDJ68053.1 - 9 4.3 120.0 0.036 12.2 34.3 4.1 4 0 0 4 4 4 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ68055.1 - 0.49 8.5 28.3 0.62 8.2 19.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNA_pol_Rpc4 PF05132.9 CDJ68055.1 - 1.1 9.2 14.8 0.21 11.5 5.3 2.8 3 0 0 3 3 3 0 RNA polymerase III RPC4 Spore_YhcN_YlaJ PF09580.5 CDJ68055.1 - 8.3 6.4 9.5 17 5.4 6.6 1.5 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3336 PF11815.3 CDJ68056.1 - 1.3e-18 66.9 0.2 2.1e-18 66.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CDJ68056.1 - 7.8e-14 52.0 0.3 7.8e-14 52.0 0.2 3.9 3 2 0 3 3 3 1 Patatin-like phospholipase YtxH PF12732.2 CDJ68056.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.5 3 1 0 3 3 3 0 YtxH-like protein Ribosomal_L2_C PF03947.13 CDJ68058.1 - 1.8e-15 56.9 0.0 3.7e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CDJ68058.1 - 4.4e-06 26.5 0.0 9.3e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SR-25 PF10500.4 CDJ68058.1 - 0.0017 17.8 27.6 0.062 12.7 13.6 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 CDJ68058.1 - 0.064 10.9 9.3 0.099 10.3 6.4 1.2 1 0 0 1 1 1 0 Ycf1 zf-DHHC PF01529.15 CDJ68058.1 - 0.9 8.9 6.8 2.9 7.2 0.0 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Herpes_UL87 PF03043.9 CDJ68058.1 - 1.4 7.2 9.5 1.8 6.8 6.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4512 PF14975.1 CDJ68058.1 - 8.6 7.2 11.5 11 6.9 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) CDK2AP PF09806.4 CDJ68059.1 - 0.00064 20.0 10.9 0.00069 19.8 7.6 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein DUF601 PF04642.7 CDJ68059.1 - 0.0037 16.6 1.4 0.0044 16.4 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF601 Pex14_N PF04695.8 CDJ68059.1 - 0.0091 16.0 8.8 0.011 15.7 6.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Chorion_2 PF03964.10 CDJ68059.1 - 0.012 16.1 9.2 0.016 15.6 6.4 1.3 1 0 0 1 1 1 0 Chorion family 2 FAM117 PF15388.1 CDJ68059.1 - 0.023 13.9 10.2 0.026 13.7 7.1 1.0 1 0 0 1 1 1 0 Protein Family FAM117 Arv1 PF04161.8 CDJ68059.1 - 0.023 14.6 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Arv1-like family NPR3 PF03666.8 CDJ68059.1 - 0.055 12.0 2.3 0.063 11.8 1.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SoxE PF06525.6 CDJ68059.1 - 0.057 12.7 4.7 0.072 12.3 3.2 1.0 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Spore_coat_CotO PF14153.1 CDJ68059.1 - 0.066 12.6 2.1 0.069 12.5 1.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF572 PF04502.8 CDJ68059.1 - 0.067 12.4 1.9 0.066 12.4 1.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) AflR PF08493.5 CDJ68059.1 - 0.075 12.0 7.1 0.095 11.7 4.9 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF4401 PF14351.1 CDJ68059.1 - 0.09 11.7 0.0 0.1 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF912 PF06024.7 CDJ68059.1 - 0.2 11.7 3.6 0.28 11.2 2.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1180 PF06679.7 CDJ68059.1 - 0.26 11.1 2.5 0.31 10.9 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Kei1 PF08552.6 CDJ68059.1 - 0.35 10.5 5.4 0.4 10.3 3.7 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_S8 PF00082.17 CDJ68059.1 - 0.44 9.6 4.8 0.49 9.5 3.3 1.1 1 0 0 1 1 1 0 Subtilase family Suf PF05843.9 CDJ68059.1 - 0.5 10.0 3.7 0.6 9.7 2.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1183 PF06682.7 CDJ68059.1 - 0.59 9.6 6.5 0.67 9.5 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Glypican PF01153.14 CDJ68059.1 - 0.79 8.2 5.1 0.89 8.0 3.6 1.0 1 0 0 1 1 1 0 Glypican RIC3 PF15361.1 CDJ68059.1 - 1.3 9.2 7.8 1.6 8.9 5.4 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF822 PF05687.8 CDJ68059.1 - 1.4 9.3 6.7 1.7 8.9 4.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Pex26 PF07163.7 CDJ68059.1 - 1.6 7.5 7.9 2 7.2 5.5 1.0 1 0 0 1 1 1 0 Pex26 protein DUF4357 PF14267.1 CDJ68059.1 - 2.4 7.7 6.4 4.9 6.8 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4357) Myco_19_kDa PF05481.7 CDJ68059.1 - 2.8 7.7 7.7 3.4 7.4 5.4 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen RED_N PF07808.8 CDJ68059.1 - 3.5 6.7 6.3 4 6.6 4.4 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region OATP PF03137.15 CDJ68059.1 - 6.9 4.5 7.7 8.4 4.3 5.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Asp_protease_2 PF13650.1 CDJ68060.1 - 1.5e-09 38.2 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ68060.1 - 6.5e-08 32.2 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ68060.1 - 2.6e-06 27.2 0.0 9.6e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ68060.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease SR-25 PF10500.4 CDJ68061.1 - 0.0066 15.9 48.7 0.034 13.5 33.8 2.0 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tmemb_cc2 PF10267.4 CDJ68061.1 - 0.04 12.5 28.6 0.051 12.1 19.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Sporozoite_P67 PF05642.6 CDJ68061.1 - 0.1 10.4 15.1 0.18 9.6 10.5 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Plasmodium_Vir PF05795.6 CDJ68061.1 - 1.1 8.3 7.5 1.4 7.9 5.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2217 PF10265.4 CDJ68061.1 - 2.2 6.9 30.2 2.5 6.7 20.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF316 PF03761.10 CDJ68062.1 - 2.9 7.1 8.2 3.2 7.0 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF316) FAM60A PF15396.1 CDJ68062.1 - 3.5 7.3 18.5 3.8 7.1 12.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A FYDLN_acid PF09538.5 CDJ68062.1 - 4 8.0 7.7 4.9 7.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF3043 PF11241.3 CDJ68062.1 - 6.5 6.3 13.8 7.6 6.0 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) vMSA PF00695.14 CDJ68062.1 - 6.5 5.8 14.4 7 5.7 10.0 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Kei1 PF08552.6 CDJ68062.1 - 9.3 5.8 15.7 11 5.6 10.9 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RskA PF10099.4 CDJ68063.1 - 0.00045 19.9 1.9 0.00045 19.9 1.3 2.3 2 0 0 2 2 2 1 Anti-sigma-K factor rskA DUF3357 PF11837.3 CDJ68063.1 - 0.0031 17.3 11.1 0.0034 17.2 0.1 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3357) CAF-1_p150 PF11600.3 CDJ68063.1 - 0.01 15.2 9.7 0.01 15.2 6.7 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0093 PF03653.8 CDJ68063.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) UCR_Fe-S_N PF10399.4 CDJ68063.1 - 0.14 11.3 0.3 0.14 11.3 0.2 3.8 2 1 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SOBP PF15279.1 CDJ68063.1 - 0.19 12.1 8.1 0.22 11.8 5.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Herpes_US9 PF06072.6 CDJ68063.1 - 0.28 11.0 6.8 0.13 12.0 0.8 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 TFIIA PF03153.8 CDJ68063.1 - 6.3 6.5 15.3 8.4 6.1 10.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit U1snRNP70_N PF12220.3 CDJ68064.1 - 0.011 16.0 4.0 0.011 16.0 2.8 1.0 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Transposase_1 PF01359.13 CDJ68064.1 - 0.019 14.7 3.8 0.054 13.2 2.6 1.8 1 1 0 1 1 1 0 Transposase (partial DDE domain) DUF4274 PF14096.1 CDJ68064.1 - 0.066 13.0 0.0 0.066 13.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4274) HXXSHH PF07586.6 CDJ68064.1 - 0.095 11.6 5.5 0.098 11.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF918 PF06033.6 CDJ68064.1 - 0.11 12.0 1.1 0.12 11.9 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) DUF788 PF05620.6 CDJ68064.1 - 0.44 10.4 3.2 0.48 10.2 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) SPATA24 PF15175.1 CDJ68064.1 - 0.63 9.7 8.9 0.69 9.5 6.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Suf PF05843.9 CDJ68064.1 - 2.4 7.8 9.2 2.4 7.8 6.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 CDJ68064.1 - 2.4 6.4 6.2 2.9 6.2 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.4 CDJ68065.1 - 0.2 11.0 3.9 0.25 10.7 2.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FlxA PF14282.1 CDJ68065.1 - 2.6 8.0 5.8 3.9 7.4 4.0 1.3 1 0 0 1 1 1 0 FlxA-like protein FLO_LFY PF01698.11 CDJ68066.1 - 0.019 13.8 5.4 0.021 13.7 3.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FAD-SLDH PF12318.3 CDJ68066.1 - 0.019 14.6 13.4 1.2 8.8 8.9 2.2 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Symplekin_C PF12295.3 CDJ68066.1 - 0.022 14.6 1.6 0.037 13.9 1.1 1.4 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal RdRP PF05183.7 CDJ68066.1 - 0.088 11.4 2.1 0.11 11.2 1.4 1.3 1 0 0 1 1 1 0 RNA dependent RNA polymerase 7TM_GPCR_Srv PF10323.4 CDJ68066.1 - 0.17 10.9 1.0 0.24 10.4 0.7 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Dala_Dala_lig_N PF01820.16 CDJ68066.1 - 0.22 11.8 3.1 0.42 10.9 2.1 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Cwf_Cwc_15 PF04889.7 CDJ68066.1 - 0.31 10.7 14.3 0.51 10.0 9.9 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.14 CDJ68066.1 - 0.53 10.0 8.6 0.71 9.6 6.0 1.1 1 0 0 1 1 1 0 SPX domain DDHD PF02862.12 CDJ68066.1 - 0.58 9.9 5.5 0.7 9.6 3.8 1.2 1 0 0 1 1 1 0 DDHD domain Baculo_PP31 PF05311.6 CDJ68066.1 - 0.84 8.8 7.8 1.3 8.2 5.4 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SseC PF04888.7 CDJ68066.1 - 1.4 8.2 13.2 2.4 7.4 9.2 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Suf PF05843.9 CDJ68066.1 - 1.6 8.3 11.4 2.2 7.9 7.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LMBR1 PF04791.11 CDJ68066.1 - 1.6 7.2 6.3 1.9 6.9 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6 PF04111.7 CDJ68066.1 - 2 7.3 14.8 2.8 6.9 10.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BAF1_ABF1 PF04684.8 CDJ68066.1 - 2.4 6.8 14.1 3.2 6.4 9.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3270 PF11674.3 CDJ68066.1 - 4.5 7.3 10.1 0.44 10.5 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) AAA_23 PF13476.1 CDJ68066.1 - 7.1 6.8 14.1 8.9 6.5 9.8 1.2 1 0 0 1 1 1 0 AAA domain SseC PF04888.7 CDJ68067.1 - 0.0021 17.4 30.3 0.0033 16.8 21.0 1.3 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Activator_LAG-3 PF11498.3 CDJ68067.1 - 0.011 14.5 18.3 0.015 14.1 12.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Peptidase_S64 PF08192.6 CDJ68067.1 - 0.82 7.9 3.5 0.85 7.8 2.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Claudin_2 PF13903.1 CDJ68067.1 - 1.4 8.6 9.4 3.2 7.4 6.4 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ACPS PF01648.15 CDJ68068.1 - 5.2e-13 48.8 0.3 3e-12 46.3 0.2 2.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily UPF0054 PF02130.12 CDJ68068.1 - 0.013 14.7 0.0 0.051 12.8 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein family UPF0054 PAT1 PF09770.4 CDJ68069.1 - 1.8 6.7 66.3 2.4 6.2 46.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Isy1 PF06246.7 CDJ68069.1 - 2.2 7.6 29.9 1 8.6 16.4 2.0 2 0 0 2 2 2 0 Isy1-like splicing family N6_N4_Mtase PF01555.13 CDJ68069.1 - 2.6 7.4 6.9 43 3.4 4.8 2.5 1 1 0 1 1 1 0 DNA methylase MARVEL PF01284.18 CDJ68070.1 - 0.043 13.6 2.0 0.054 13.3 1.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF3357 PF11837.3 CDJ68070.1 - 0.092 12.6 6.0 1.4 8.7 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Pex14_N PF04695.8 CDJ68070.1 - 0.15 12.1 9.6 0.19 11.7 6.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lamp PF01299.12 CDJ68070.1 - 0.72 8.9 4.2 0.83 8.7 2.9 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF2217 PF10265.4 CDJ68070.1 - 0.94 8.1 4.3 1.1 7.9 3.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MCPVI PF02993.9 CDJ68070.1 - 2 8.5 12.0 2.2 8.3 8.3 1.0 1 0 0 1 1 1 0 Minor capsid protein VI TrbC PF04956.8 CDJ68070.1 - 5.2 7.1 13.9 3 7.9 1.2 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family TPPK_C PF12555.3 CDJ68070.1 - 5.6 6.7 17.2 3.6 7.3 0.9 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Herpes_gE PF02480.11 CDJ68070.1 - 7.3 4.7 7.0 1.9 6.6 1.2 1.8 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Gly-zipper_OmpA PF13436.1 CDJ68070.1 - 8.6 6.0 30.6 4.2 7.0 5.6 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF4366 PF14283.1 CDJ68070.1 - 9.4 5.5 8.4 11 5.3 5.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Kelch_5 PF13854.1 CDJ68071.1 - 1.1e-22 79.4 1.1 5.7e-06 26.1 0.0 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 CDJ68071.1 - 5.6e-20 70.8 3.2 1.5e-09 37.4 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CDJ68071.1 - 6.5e-19 67.5 18.4 8.2e-05 22.6 0.0 7.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CDJ68071.1 - 4.3e-15 54.7 13.9 5.4e-07 29.1 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CDJ68071.1 - 1.6e-14 53.1 0.0 1.1e-05 24.9 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 CDJ68071.1 - 4.1e-11 42.5 0.4 0.0024 17.9 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CDJ68072.1 - 4.8e-33 112.6 0.2 1.5e-09 37.4 0.4 4.2 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CDJ68072.1 - 5.3e-32 109.2 3.7 9.7e-09 35.1 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ68072.1 - 4.4e-29 99.9 0.4 2.6e-08 33.6 0.1 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 CDJ68072.1 - 8.8e-27 92.1 0.3 5.1e-08 32.7 0.2 4.2 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 CDJ68072.1 - 1.1e-19 69.4 1.8 3.3e-08 32.9 0.1 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 CDJ68072.1 - 1.1e-19 69.6 1.5 5e-06 25.9 0.0 4.7 4 1 0 4 4 4 4 Kelch motif Ribosomal_S25 PF03297.10 CDJ68073.1 - 6.5e-37 125.7 0.6 1e-36 125.1 0.4 1.3 1 0 0 1 1 1 1 S25 ribosomal protein DEAD PF00270.24 CDJ68074.1 - 4.4e-31 107.6 2.4 9.1e-31 106.6 1.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ68074.1 - 5.5e-17 61.4 0.0 3.6e-15 55.5 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CDJ68074.1 - 0.00057 20.0 0.4 0.0038 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain SIS PF01380.17 CDJ68074.1 - 0.0084 15.7 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 SIS domain ResIII PF04851.10 CDJ68074.1 - 0.0095 15.7 0.5 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CDJ68074.1 - 0.051 12.5 0.1 0.19 10.6 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 CDJ68074.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 CDJ68074.1 - 3.5 7.2 6.8 10 5.7 4.7 1.8 1 1 0 1 1 1 0 NACHT domain Phage_integrase PF00589.17 CDJ68075.1 - 7.3e-11 42.0 0.0 1.3e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family SAP PF02037.22 CDJ68075.1 - 2e-05 23.9 0.3 5.5e-05 22.5 0.2 1.7 1 0 0 1 1 1 1 SAP domain DZR PF12773.2 CDJ68075.1 - 5.1e-05 23.0 0.2 0.00012 21.7 0.1 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CDJ68075.1 - 6.3e-05 22.3 1.0 0.00014 21.2 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 CDJ68075.1 - 0.00017 20.7 0.9 0.00037 19.6 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-DHHC PF01529.15 CDJ68075.1 - 0.0029 17.0 0.2 0.0046 16.3 0.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase NOB1_Zn_bind PF08772.6 CDJ68075.1 - 0.063 13.1 1.5 0.15 11.8 1.0 1.6 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 CDJ68075.1 - 0.26 10.8 0.1 0.26 10.8 0.0 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain UQ_con PF00179.21 CDJ68077.1 - 1.2e-23 83.1 0.0 2.2e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SR-25 PF10500.4 CDJ68077.1 - 0.0061 16.0 4.2 0.0061 16.0 2.9 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CDJ68077.1 - 0.01 16.1 17.4 0.034 14.3 1.4 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Prok-E2_B PF14461.1 CDJ68077.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 CDJ68077.1 - 0.057 13.3 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF566 PF04484.7 CDJ68077.1 - 4.2 6.7 15.5 8.7 5.7 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF566) Chromo PF00385.19 CDJ68078.1 - 1.1e-12 47.3 0.0 2.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDJ68078.1 - 0.014 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 CDJ68079.1 - 4.3e-17 62.1 0.0 8.8e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT PF03062.14 CDJ68080.1 - 7.8e-25 87.6 17.6 9.5e-25 87.3 12.2 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CDJ68080.1 - 1.5e-05 24.9 7.4 1.6e-05 24.8 3.8 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF4557 PF15101.1 CDJ68080.1 - 0.83 9.4 5.4 1.1 9.0 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2737 PF10930.3 CDJ68081.1 - 0.14 11.7 1.1 0.38 10.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) Methyltransf_10 PF05971.7 CDJ68082.1 - 3.3e-60 203.7 0.3 1.2e-38 132.9 0.0 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 CDJ68082.1 - 2.2e-05 24.4 0.0 2.2e-05 24.4 0.0 2.8 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ68082.1 - 0.00045 20.7 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ68082.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ68082.1 - 0.026 15.0 0.0 0.059 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CDJ68082.1 - 0.028 13.7 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 CDJ68082.1 - 0.04 14.2 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 CDJ68082.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 CDJ68082.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Raftlin PF15250.1 CDJ68082.1 - 0.18 10.3 0.5 0.31 9.5 0.4 1.3 1 0 0 1 1 1 0 Raftlin SR-25 PF10500.4 CDJ68082.1 - 0.48 9.8 42.2 0.19 11.1 7.0 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ68082.1 - 0.48 10.4 32.7 0.18 11.8 7.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.14 CDJ68084.1 - 0.00011 22.5 25.1 0.0028 17.9 3.8 2.9 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF3661 PF12400.3 CDJ68085.1 - 1.1e-13 51.3 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Vaculolar membrane protein Retrotrans_gag PF03732.12 CDJ68087.1 - 1.2e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CDJ68087.1 - 4.6e-05 23.1 2.2 4.6e-05 23.1 1.6 2.9 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ68087.1 - 0.021 14.5 0.3 0.021 14.5 0.2 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ68087.1 - 0.14 11.8 0.4 0.14 11.8 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ68087.1 - 0.4 10.3 9.1 0.49 10.0 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Tfb4 PF03850.9 CDJ68088.1 - 0.32 10.2 6.5 0.34 10.1 4.5 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 Adaptin_binding PF10199.4 CDJ68088.1 - 0.46 10.7 16.6 0.54 10.5 11.5 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Asp-B-Hydro_N PF05279.6 CDJ68088.1 - 2.1 8.1 10.7 2.4 7.9 7.4 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Tim54 PF11711.3 CDJ68088.1 - 2.1 6.8 10.4 2.1 6.8 7.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4045 PF13254.1 CDJ68088.1 - 2.5 7.2 15.0 2.6 7.2 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BTV_NS2 PF04514.7 CDJ68088.1 - 3.8 6.3 11.8 3.8 6.3 8.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Mnd1 PF03962.10 CDJ68088.1 - 4 7.0 22.7 4.4 6.9 15.7 1.0 1 0 0 1 1 1 0 Mnd1 family Lin-8 PF03353.10 CDJ68088.1 - 4.5 6.4 20.2 4.9 6.3 14.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NARP1 PF12569.3 CDJ68088.1 - 4.8 5.8 16.0 5 5.7 11.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM60A PF15396.1 CDJ68088.1 - 5.3 6.7 15.3 6.2 6.5 10.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF822 PF05687.8 CDJ68088.1 - 7 7.0 14.1 7.6 6.8 9.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) FAM176 PF14851.1 CDJ68088.1 - 7 6.3 8.6 9.4 5.8 6.0 1.3 1 0 0 1 1 1 0 FAM176 family Hid1 PF12722.2 CDJ68088.1 - 7.9 4.0 18.5 8.7 3.8 12.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDJ68088.1 - 8 4.8 16.3 8.5 4.7 11.3 1.0 1 0 0 1 1 1 0 Raftlin Spore_coat_CotO PF14153.1 CDJ68088.1 - 9.4 5.6 24.7 11 5.3 17.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 CDJ68088.1 - 9.4 4.1 17.1 10 4.0 11.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RLI PF04068.10 CDJ68089.1 - 5.8e-07 28.9 0.1 1.2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Aldedh PF00171.17 CDJ68090.1 - 7.2e-33 113.6 0.1 7.8e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-RVT PF13966.1 CDJ68091.1 - 1.3e-06 28.6 0.3 4e-06 27.0 0.2 1.9 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase Prp31_C PF09785.4 CDJ68092.1 - 5e-22 78.6 6.5 5.8e-16 59.0 3.9 2.5 1 1 1 2 2 2 2 Prp31 C terminal domain Nop PF01798.13 CDJ68092.1 - 6.2e-07 28.8 0.4 1e-06 28.1 0.3 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain Collagen PF01391.13 CDJ68093.1 - 3.1e-05 23.4 19.9 3.1e-05 23.4 13.8 4.0 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) CytochromB561_N PF09786.4 CDJ68093.1 - 0.15 10.5 4.6 0.22 9.9 3.2 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ashwin PF15323.1 CDJ68093.1 - 6.5 6.6 9.8 10 6.0 6.8 1.2 1 0 0 1 1 1 0 Developmental protein Sporozoite_P67 PF05642.6 CDJ68094.1 - 0.0053 14.7 0.0 0.0053 14.7 0.0 2.8 2 1 1 3 3 3 1 Sporozoite P67 surface antigen SR-25 PF10500.4 CDJ68095.1 - 4.2 6.7 48.4 0.37 10.2 4.9 3.3 2 2 0 2 2 2 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.8 CDJ68096.1 - 1.4 9.3 12.9 3.5 8.0 1.4 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Ribosomal_L4 PF00573.17 CDJ68097.1 - 7.7e-30 103.7 0.1 7.7e-30 103.7 0.1 1.9 2 1 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CDJ68097.1 - 3.2e-17 62.1 8.5 1.2e-16 60.3 5.9 2.0 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain DUF607 PF04678.8 CDJ68097.1 - 1.1 9.1 5.8 2.6 7.9 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF607 NAC PF01849.13 CDJ68098.1 - 9.1e-12 44.3 0.0 1.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 NAC domain Ctr PF04145.10 CDJ68098.1 - 0.058 13.4 0.8 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 Ctr copper transporter family Cuticle_3 PF11018.3 CDJ68098.1 - 0.12 12.5 6.5 0.19 11.8 4.5 1.3 1 0 0 1 1 1 0 Pupal cuticle protein C1 MRP-S31 PF15433.1 CDJ68098.1 - 0.2 11.0 10.0 0.034 13.5 2.0 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Succ_CoA_lig PF13607.1 CDJ68098.1 - 0.2 11.2 4.7 0.057 13.0 0.7 1.8 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain FAD-SLDH PF12318.3 CDJ68098.1 - 0.42 10.2 9.0 0.65 9.6 2.2 2.1 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Uds1 PF15456.1 CDJ68098.1 - 0.82 9.6 9.5 0.47 10.4 1.1 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Phostensin_N PF13916.1 CDJ68098.1 - 1.9 8.5 8.1 0.098 12.6 1.4 1.9 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF4404 PF14357.1 CDJ68098.1 - 1.9 8.9 11.5 0.65 10.4 3.8 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4404) TFIIA PF03153.8 CDJ68098.1 - 3 7.6 13.8 3.8 7.3 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GRIN_C PF15235.1 CDJ68098.1 - 4.9 7.2 9.5 0.39 10.7 2.2 2.0 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus Thioredoxin_6 PF13848.1 CDJ68099.1 - 3.3e-06 27.0 0.0 1.8e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.15 CDJ68099.1 - 0.022 14.4 0.0 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin CDK2AP PF09806.4 CDJ68100.1 - 0.33 11.1 19.8 0.069 13.3 0.8 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein FCP1_C PF09309.5 CDJ68101.1 - 0.05 12.9 12.7 0.059 12.6 8.8 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DDRGK PF09756.4 CDJ68101.1 - 0.21 10.9 15.0 0.23 10.8 10.4 1.1 1 0 0 1 1 1 0 DDRGK domain Med15 PF09606.5 CDJ68101.1 - 1.3 7.1 48.1 1.6 6.8 33.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex16 PF08610.5 CDJ68101.1 - 1.4 7.8 10.8 1.4 7.8 7.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ycf1 PF05758.7 CDJ68101.1 - 2.3 5.8 10.3 2.1 5.9 7.2 1.0 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 CDJ68101.1 - 2.7 7.5 20.9 3 7.3 14.5 1.1 1 0 0 1 1 1 0 IncA protein Paf1 PF03985.8 CDJ68101.1 - 3.1 6.4 13.2 3.1 6.4 9.2 1.2 1 0 0 1 1 1 0 Paf1 UPF0560 PF10577.4 CDJ68101.1 - 3.4 5.8 20.1 3.4 5.8 13.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Plasmodium_Vir PF05795.6 CDJ68101.1 - 3.9 6.5 6.1 4 6.5 4.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.7 CDJ68101.1 - 4.3 5.8 18.7 4.5 5.7 13.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4045 PF13254.1 CDJ68101.1 - 7.6 5.6 18.2 9.5 5.3 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Bul1_N PF04425.7 CDJ68101.1 - 9.9 4.5 10.7 11 4.4 7.4 1.2 1 0 0 1 1 1 0 Bul1 N terminus Ribonuc_red_sm PF00268.16 CDJ68102.1 - 6.2e-05 22.1 0.0 8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain FtsJ PF01728.14 CDJ68105.1 - 1.4e-53 181.5 0.7 2.6e-53 180.7 0.5 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Zip PF02535.17 CDJ68105.1 - 0.037 13.0 0.3 0.61 9.0 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter PAT1 PF09770.4 CDJ68105.1 - 0.28 9.3 60.8 0.24 9.6 22.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDJ68105.1 - 0.39 10.4 14.8 0.93 9.2 0.7 2.2 2 0 0 2 2 2 0 DDHD domain DUF1183 PF06682.7 CDJ68105.1 - 3.5 7.1 18.9 2.1 7.8 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1183) RIC3 PF15361.1 CDJ68105.1 - 7.4 6.7 21.9 1.7 8.8 7.5 3.3 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 eIF-3_zeta PF05091.7 CDJ68105.1 - 7.6 5.0 22.6 4.4 5.7 2.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spore_coat_CotO PF14153.1 CDJ68105.1 - 9.3 5.6 28.8 0.76 9.1 8.7 3.1 3 0 0 3 3 3 0 Spore coat protein CotO Vps5 PF09325.5 CDJ68107.1 - 0.26 10.5 1.8 0.54 9.4 1.2 1.6 1 1 0 1 1 1 0 Vps5 C terminal like Pheromone PF08015.6 CDJ68107.1 - 9.1 7.1 11.4 14 6.5 7.9 1.3 1 0 0 1 1 1 0 Fungal mating-type pheromone Chromo PF00385.19 CDJ68108.1 - 3.9e-11 42.4 0.0 8.5e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_L14 PF00238.14 CDJ68110.1 - 4.4e-33 113.6 0.0 5e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PARG_cat PF05028.9 CDJ68111.1 - 1.7e-41 142.6 0.0 6.7e-22 78.1 0.0 3.2 4 0 0 4 4 4 2 Poly (ADP-ribose) glycohydrolase (PARG) URO-D PF01208.12 CDJ68112.1 - 3e-99 332.2 0.0 4.1e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Pro_isomerase PF00160.16 CDJ68115.1 - 5.6e-47 159.8 0.1 6.4e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Methyltransf_16 PF10294.4 CDJ68116.1 - 0.00011 21.6 0.2 0.17 11.3 0.0 2.6 2 1 0 2 2 2 2 Putative methyltransferase PrmA PF06325.8 CDJ68116.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CDJ68116.1 - 0.051 12.9 0.0 0.15 11.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain MarR_2 PF12802.2 CDJ68117.1 - 0.12 12.0 1.9 0.13 11.9 0.2 1.9 2 0 0 2 2 2 0 MarR family Macoilin PF09726.4 CDJ68117.1 - 0.36 9.0 4.9 0.47 8.6 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Nbs1_C PF08599.5 CDJ68117.1 - 2.3 8.2 5.1 1.4 8.9 0.4 2.5 2 1 1 3 3 3 0 DNA damage repair protein Nbs1 Beach PF02138.13 CDJ68118.1 - 5.1e-64 216.3 0.0 4.6e-37 127.9 0.0 2.9 2 1 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.27 CDJ68118.1 - 0.00017 21.3 0.1 0.00094 18.9 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat PH_BEACH PF14844.1 CDJ68118.1 - 0.071 12.9 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH Surface_antigen PF11054.3 CDJ68119.1 - 2.8e-27 95.7 7.8 3e-23 82.4 3.2 3.1 2 1 0 2 2 2 2 Sporozoite TA4 surface antigen GRP PF07172.6 CDJ68119.1 - 0.0085 16.5 8.3 1.5 9.3 4.6 2.9 3 0 0 3 3 3 2 Glycine rich protein family DUF2763 PF10961.3 CDJ68119.1 - 0.068 13.5 1.1 0.75 10.2 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) BAF1_ABF1 PF04684.8 CDJ68119.1 - 0.074 11.8 0.4 0.1 11.4 0.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serglycin PF04360.7 CDJ68119.1 - 0.22 11.2 3.1 0.44 10.2 2.1 1.8 1 1 0 1 1 1 0 Serglycin Surface_antigen PF11054.3 CDJ68120.1 - 2e-34 119.1 0.1 1.9e-31 109.3 0.0 2.1 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen FBPase PF00316.15 CDJ68121.1 - 5.1e-122 406.7 0.0 5.9e-122 406.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF91 PF01939.11 CDJ68121.1 - 0.023 13.8 0.1 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF91 NdhM PF10664.4 CDJ68121.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Proteasome PF00227.21 CDJ68122.1 - 3.3e-22 78.7 0.0 3.9e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 CDJ68123.1 - 0.021 13.9 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Not3 PF04065.10 CDJ68124.1 - 3.9e-52 176.8 13.4 3.9e-52 176.8 9.3 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CDJ68124.1 - 7.2e-35 119.7 3.3 2.3e-34 118.1 2.3 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Pkinase PF00069.20 CDJ68126.1 - 7.1e-70 235.1 0.0 1.2e-69 234.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68126.1 - 3.4e-29 101.7 0.0 5.4e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDJ68126.1 - 0.0065 16.2 0.1 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CDJ68126.1 - 0.029 13.4 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HemX PF04375.9 CDJ68126.1 - 0.87 8.1 18.0 0.11 11.0 4.0 2.4 2 0 0 2 2 2 0 HemX Thioredoxin_8 PF13905.1 CDJ68127.1 - 3.1e-33 113.7 0.0 5.8e-27 93.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CDJ68127.1 - 2.3e-11 43.8 0.0 2.5e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 CDJ68127.1 - 2.2e-09 36.9 0.0 1.9e-07 30.6 0.0 3.2 2 1 1 3 3 3 1 Thioredoxin AhpC-TSA PF00578.16 CDJ68127.1 - 1.5e-08 34.3 0.0 6.4e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CDJ68127.1 - 5.6e-08 32.4 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 CDJ68127.1 - 2.7e-06 27.1 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_7 PF13899.1 CDJ68127.1 - 0.00016 21.6 0.0 0.00067 19.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like NADH_4Fe-4S PF10589.4 CDJ68127.1 - 0.023 13.8 0.0 0.063 12.4 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Thioredoxin_9 PF14595.1 CDJ68127.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin PRP4 PF08799.6 CDJ68127.1 - 0.17 11.1 1.4 0.5 9.6 0.1 2.4 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like DUF1180 PF06679.7 CDJ68128.1 - 0.054 13.3 0.3 0.054 13.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) RINGv PF12906.2 CDJ68128.1 - 0.054 13.5 4.7 0.16 12.0 3.3 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.1 CDJ68128.1 - 0.076 12.8 7.5 0.17 11.7 5.2 1.6 1 0 0 1 1 1 0 Ring finger domain Kelch_6 PF13964.1 CDJ68130.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Kelch motif Dynein_heavy PF03028.10 CDJ68131.1 - 2.6e-152 508.3 0.0 3.7e-151 504.6 0.0 2.7 2 1 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CDJ68131.1 - 1e-149 499.5 0.0 1e-149 499.5 0.0 4.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CDJ68131.1 - 5e-126 420.5 4.6 5e-126 420.5 3.2 3.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDJ68131.1 - 3e-83 278.9 0.0 9.5e-83 277.2 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CDJ68131.1 - 4e-43 146.8 0.0 8.7e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDJ68131.1 - 8.7e-38 129.8 0.0 4.8e-36 124.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 CDJ68131.1 - 2.8e-33 115.0 11.6 4.8e-33 114.3 8.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CDJ68131.1 - 1.8e-31 108.7 0.0 2.5e-11 43.4 0.0 7.0 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CDJ68131.1 - 1.4e-15 57.6 0.0 0.001 19.2 0.0 5.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDJ68131.1 - 2.2e-13 50.4 1.8 0.00064 19.8 0.0 8.0 7 1 0 7 7 7 2 AAA domain AAA_7 PF12775.2 CDJ68131.1 - 5.7e-13 48.5 0.0 1.3e-11 44.1 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_19 PF13245.1 CDJ68131.1 - 3.2e-07 29.9 0.0 0.37 10.5 0.0 5.3 4 0 0 4 4 4 2 Part of AAA domain AAA_17 PF13207.1 CDJ68131.1 - 2.3e-06 28.4 0.0 5 7.9 0.0 5.4 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CDJ68131.1 - 1.2e-05 25.5 0.2 20 5.5 0.0 5.8 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.1 CDJ68131.1 - 2.9e-05 23.9 3.6 0.46 10.3 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_14 PF13173.1 CDJ68131.1 - 0.00026 20.9 0.0 2.3 8.1 0.0 4.6 5 0 0 5 5 5 1 AAA domain Zeta_toxin PF06414.7 CDJ68131.1 - 0.00027 20.0 0.3 0.31 10.0 0.0 4.4 5 0 0 5 5 5 1 Zeta toxin AAA_25 PF13481.1 CDJ68131.1 - 0.00042 19.7 1.4 0.063 12.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.1 CDJ68131.1 - 0.0024 17.3 0.0 9.1 5.9 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CDJ68131.1 - 0.015 15.4 0.1 1e+02 3.1 0.0 4.9 4 0 0 4 4 4 0 RNA helicase Mg_chelatase PF01078.16 CDJ68131.1 - 0.024 13.7 6.4 4.8 6.2 0.0 4.5 4 1 1 5 5 5 0 Magnesium chelatase, subunit ChlI Reo_sigmaC PF04582.7 CDJ68131.1 - 0.12 11.5 4.1 2.3 7.3 0.5 3.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Atg14 PF10186.4 CDJ68131.1 - 8.7 5.1 22.1 1.6 7.6 4.1 3.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L29 PF00831.18 CDJ68132.1 - 3.2e-18 65.1 1.9 3.2e-18 65.1 1.3 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein DUF4404 PF14357.1 CDJ68132.1 - 0.032 14.6 0.1 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Spc42p PF11544.3 CDJ68132.1 - 1.4 8.9 5.4 0.27 11.1 1.4 1.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p TLD PF07534.11 CDJ68133.1 - 1.2e-20 73.8 0.0 1.6e-19 70.2 0.0 2.0 2 0 0 2 2 2 1 TLD Cation_ATPase_N PF00690.21 CDJ68134.1 - 0.016 14.6 0.1 0.095 12.1 0.0 2.1 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus SUI1 PF01253.17 CDJ68135.1 - 6.7e-15 54.6 0.7 2.3e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 TMEM154 PF15102.1 CDJ68138.1 - 0.003 17.2 0.1 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF3481 PF11980.3 CDJ68138.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) SR-25 PF10500.4 CDJ68138.1 - 0.48 9.8 14.7 0.99 8.8 10.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.6 CDJ68138.1 - 0.78 7.7 8.2 1 7.3 5.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LHC PF00556.15 CDJ68138.1 - 1.3 8.9 5.1 2.6 7.9 3.6 1.5 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Med15 PF09606.5 CDJ68140.1 - 0.083 11.0 24.7 0.1 10.7 17.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Rab_eff_C PF04698.7 CDJ68140.1 - 0.28 9.2 4.9 0.32 9.0 3.4 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus RCR PF12273.3 CDJ68140.1 - 0.58 10.7 7.7 1.1 9.8 5.3 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PHD_3 PF13922.1 CDJ68140.1 - 1.5 9.0 8.6 7.1 6.9 0.4 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PAT1 PF09770.4 CDJ68140.1 - 3.6 5.7 20.5 3.6 5.6 14.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L39 PF00832.15 CDJ68141.1 - 5e-23 80.2 9.5 5.5e-23 80.1 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Noggin PF05806.7 CDJ68141.1 - 0.021 14.1 0.7 0.021 14.1 0.5 1.0 1 0 0 1 1 1 0 Noggin RCC1_2 PF13540.1 CDJ68142.1 - 0.0033 16.9 12.0 0.027 14.1 0.0 5.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CDJ68142.1 - 0.17 12.1 3.1 4.9 7.4 0.2 3.4 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Inhibitor_I71 PF12628.2 CDJ68143.1 - 5.4 6.6 6.3 9.4 5.8 0.0 2.9 3 0 0 3 3 3 0 Falstatin, cysteine peptidase inhibitor DUF572 PF04502.8 CDJ68145.1 - 0.013 14.6 7.5 0.016 14.4 5.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ycf1 PF05758.7 CDJ68145.1 - 0.39 8.3 4.3 0.48 8.0 3.0 1.1 1 0 0 1 1 1 0 Ycf1 DNA_pol_viral_N PF00242.12 CDJ68145.1 - 4.1 6.3 13.5 5.4 5.9 9.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RED_N PF07808.8 CDJ68145.1 - 4.7 6.3 13.5 0.67 9.1 4.1 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF445 PF04286.7 CDJ68146.1 - 0.0056 16.2 3.8 0.0056 16.2 2.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF445) Glyco_hydro_1 PF00232.13 CDJ68146.1 - 0.021 13.0 0.8 0.03 12.5 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 DUF1510 PF07423.6 CDJ68146.1 - 0.03 13.6 6.1 2.4 7.4 4.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) Rtt102p PF09510.5 CDJ68146.1 - 0.17 11.8 4.7 0.052 13.5 0.9 1.8 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein DUF4367 PF14285.1 CDJ68146.1 - 0.75 9.0 6.1 0.59 9.4 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4367) Presenilin PF01080.12 CDJ68146.1 - 0.77 8.5 12.8 0.7 8.6 4.0 2.3 2 0 0 2 2 2 0 Presenilin DUF1151 PF06625.6 CDJ68146.1 - 1.8 8.2 21.0 0.15 11.8 9.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Peptidase_U57 PF05582.7 CDJ68146.1 - 2.4 7.0 5.8 5.5 5.8 4.0 1.5 1 0 0 1 1 1 0 YabG peptidase U57 YebO PF13974.1 CDJ68148.1 - 0.03 14.1 4.0 2.2 8.1 0.4 2.4 2 0 0 2 2 2 0 YebO-like protein IalB PF06776.7 CDJ68148.1 - 0.15 11.9 0.4 0.15 11.9 0.2 1.7 2 0 0 2 2 2 0 Invasion associated locus B (IalB) protein Ribosomal_60s PF00428.14 CDJ68150.1 - 0.61 10.5 16.3 3.5 8.0 3.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.27 CDJ68151.1 - 0.0064 16.3 3.8 14 5.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PUF PF00806.14 CDJ68152.1 - 6.3e-42 138.7 5.6 3.8e-06 26.0 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat Pkinase PF00069.20 CDJ68153.1 - 1.9e-33 115.7 0.0 3.8e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68153.1 - 5.8e-16 58.3 0.0 4.2e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDJ68153.1 - 2e-06 27.0 0.0 0.0003 19.8 0.1 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CDJ68153.1 - 0.00015 21.6 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Med4 PF10018.4 CDJ68153.1 - 0.0018 17.7 1.6 0.0038 16.6 1.1 1.5 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Seadorna_VP7 PF07387.6 CDJ68153.1 - 0.33 9.7 0.0 0.51 9.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FRQ PF09421.5 CDJ68154.1 - 0.017 12.9 0.5 0.018 12.8 0.3 1.0 1 0 0 1 1 1 0 Frequency clock protein DUF3043 PF11241.3 CDJ68154.1 - 0.066 12.7 1.0 0.08 12.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) SGT1 PF07093.6 CDJ68156.1 - 0.67 8.2 20.5 0.71 8.1 14.2 1.0 1 0 0 1 1 1 0 SGT1 protein SR-25 PF10500.4 CDJ68156.1 - 3.4 7.0 18.4 4.1 6.8 12.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SCF PF02404.10 CDJ68157.1 - 0.14 11.2 0.6 0.51 9.4 0.4 1.9 1 0 0 1 1 1 0 Stem cell factor UPF0561 PF10573.4 CDJ68159.1 - 1.2e-07 31.6 14.6 0.26 11.1 0.3 4.2 4 0 0 4 4 4 4 Uncharacterised protein family UPF0561 Crust_neuro_H PF03858.8 CDJ68159.1 - 9e-06 26.1 12.8 2.4 8.8 0.2 5.2 4 0 0 4 4 4 4 Crustacean neurohormone H Afaf PF15339.1 CDJ68159.1 - 0.00021 20.9 3.6 2.5 7.6 0.0 4.0 4 0 0 4 4 4 2 Acrosome formation-associated factor Tir_receptor_N PF07490.6 CDJ68159.1 - 0.00022 20.9 14.7 0.053 13.1 0.8 3.2 3 0 0 3 3 3 3 Translocated intimin receptor (Tir) N-terminus CobS_N PF12556.3 CDJ68159.1 - 0.0028 17.0 2.5 37 3.8 0.0 4.3 4 0 0 4 4 4 0 Cobaltochelatase CobS subunit N terminal Surface_antigen PF11054.3 CDJ68160.1 - 1.2e-53 182.1 0.9 1.3e-53 181.9 0.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Radical_SAM PF04055.16 CDJ68162.1 - 0.21 11.7 4.3 3.9 7.6 1.0 2.3 2 0 0 2 2 2 0 Radical SAM superfamily DUF3235 PF11574.3 CDJ68163.1 - 0.028 14.6 4.2 0.031 14.4 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) TraT PF05818.7 CDJ68163.1 - 0.35 10.2 6.6 0.38 10.1 4.6 1.0 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein PepSY_2 PF13670.1 CDJ68163.1 - 0.42 10.5 10.4 0.5 10.3 7.2 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF4367 PF14285.1 CDJ68163.1 - 0.58 9.4 2.0 0.67 9.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) MSP1_C PF07462.6 CDJ68163.1 - 2.8 6.2 4.7 2.7 6.2 3.3 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus cNMP_binding PF00027.24 CDJ68164.1 - 2.3e-08 33.7 0.0 2.5e-07 30.4 0.0 2.6 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain IER PF05760.7 CDJ68165.1 - 0.34 10.7 4.3 0.42 10.5 3.0 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF3022 PF11226.3 CDJ68166.1 - 0.13 12.1 0.2 0.17 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) Ribosomal_L9_N PF01281.14 CDJ68167.1 - 7.2e-11 41.1 0.0 1.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF2722 PF10846.3 CDJ68167.1 - 0.0064 15.5 1.2 0.06 12.3 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Med15 PF09606.5 CDJ68167.1 - 0.045 11.9 19.7 0.014 13.6 5.8 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ68167.1 - 0.068 12.5 2.6 0.69 9.2 0.5 2.1 2 0 0 2 2 2 0 Spt20 family Activator_LAG-3 PF11498.3 CDJ68167.1 - 8.5 5.0 29.1 5.6 5.5 1.7 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 RNA_pol_Rpc34 PF05158.7 CDJ68168.1 - 1.6e-46 159.0 0.2 1.3e-43 149.4 0.1 2.5 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit UBA_3 PF09288.5 CDJ68168.1 - 0.055 13.0 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Skp1 PF01466.14 CDJ68169.1 - 6e-28 96.7 0.1 1.1e-27 95.8 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CDJ68169.1 - 4.1e-21 74.8 0.2 8.7e-21 73.7 0.1 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 CDJ68169.1 - 0.021 14.8 0.3 0.94 9.4 0.0 2.5 2 1 0 2 2 2 0 BTB/POZ domain Rubella_E2 PF05749.6 CDJ68169.1 - 0.23 10.6 3.6 6.1 6.0 0.8 2.1 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 HdeA PF06411.6 CDJ68169.1 - 0.5 10.3 10.3 0.91 9.5 0.0 2.5 2 1 0 2 2 2 0 HdeA/HdeB family CbiZ PF01955.13 CDJ68170.1 - 0.32 10.7 10.7 0.12 12.1 4.4 2.4 3 0 0 3 3 3 0 Adenosylcobinamide amidohydrolase Acyltransferase PF01553.16 CDJ68171.1 - 9.5e-05 21.8 0.0 0.0002 20.7 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase IncA PF04156.9 CDJ68172.1 - 3.2e-05 23.6 6.3 3.2e-05 23.6 4.4 3.0 3 0 0 3 3 3 1 IncA protein PEHE PF15275.1 CDJ68172.1 - 0.43 11.0 12.0 1.3 9.5 8.3 1.8 1 0 0 1 1 1 0 PEHE domain DUF2232 PF09991.4 CDJ68172.1 - 1.1 8.2 4.9 0.71 8.8 1.9 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) DUF2215 PF10225.4 CDJ68172.1 - 6.1 6.2 7.0 10 5.4 4.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF106 PF01956.11 CDJ68172.1 - 8.9 5.8 8.6 17 4.9 6.0 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 DnaJ PF00226.26 CDJ68173.1 - 0.00028 20.5 1.7 0.00063 19.4 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain DUF508 PF04370.7 CDJ68173.1 - 0.77 9.3 4.8 2.9 7.4 3.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF508) AAA PF00004.24 CDJ68174.1 - 2.9e-07 30.7 3.1 0.005 17.0 0.0 4.4 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) zf-HC5HC2H_2 PF13832.1 CDJ68175.1 - 5.8e-11 42.3 8.8 1.2e-07 31.7 0.0 3.8 4 0 0 4 4 4 2 PHD-zinc-finger like domain PHD_2 PF13831.1 CDJ68175.1 - 1.6e-09 36.9 1.9 1.6e-09 36.9 1.3 4.2 5 0 0 5 5 5 1 PHD-finger PHD PF00628.24 CDJ68175.1 - 7.1e-09 35.2 5.4 7.1e-09 35.2 3.7 3.7 4 0 0 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.1 CDJ68175.1 - 1.5e-05 25.0 6.5 1.5e-05 25.0 4.5 4.7 5 0 0 5 5 5 1 PHD-like zinc-binding domain C1_1 PF00130.17 CDJ68175.1 - 0.0011 18.6 0.1 0.0011 18.6 0.1 4.0 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DHQS PF01959.11 CDJ68178.1 - 0.2 10.3 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) Cytochrom_C1 PF02167.10 CDJ68179.1 - 8.5e-76 254.4 0.0 1.7e-75 253.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CDJ68179.1 - 0.0025 17.9 0.0 0.0054 16.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CDJ68179.1 - 0.021 15.6 0.0 0.045 14.5 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c Sulfate_transp PF00916.15 CDJ68180.1 - 9.4e-16 57.6 8.5 1.8e-15 56.6 5.9 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CDJ68180.1 - 2.4e-06 27.0 5.3 2.4e-06 27.0 3.6 2.5 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif Ufd2P_core PF10408.4 CDJ68181.1 - 2.3e-116 389.5 0.0 2.7e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CDJ68181.1 - 3.8e-27 94.0 0.9 7.4e-27 93.1 0.7 1.5 1 0 0 1 1 1 1 U-box domain zf-Tim10_DDP PF02953.10 CDJ68182.1 - 3e-15 55.2 4.7 5.6e-15 54.3 3.2 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CDJ68182.1 - 0.1 12.0 3.9 0.14 11.6 2.7 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) PIH1 PF08190.7 CDJ68183.1 - 5.6e-18 65.4 2.9 3e-15 56.5 0.0 2.9 2 2 1 3 3 3 1 pre-RNA processing PIH1/Nop17 DUF3123 PF11321.3 CDJ68183.1 - 0.0096 16.2 0.1 0.0096 16.2 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3123) IncA PF04156.9 CDJ68185.1 - 2.3e-05 24.0 6.9 2.3e-05 24.0 4.8 3.2 2 1 0 3 3 3 1 IncA protein GSK-3_bind PF05350.7 CDJ68186.1 - 0.086 12.2 0.6 0.093 12.1 0.4 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding ExoD PF06055.7 CDJ68187.1 - 0.15 11.1 0.3 12 4.9 0.0 2.4 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD DNA_pol_B PF00136.16 CDJ68190.1 - 2.6e-105 352.8 0.0 3.4e-105 352.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_alpha_N PF12254.3 CDJ68190.1 - 7.1e-17 60.9 4.0 2e-16 59.5 2.8 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.14 CDJ68190.1 - 1.4e-12 47.1 0.0 1e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DUF793 PF05633.6 CDJ68190.1 - 0.019 13.7 2.5 3.3 6.3 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF793) LIM_bind PF01803.11 CDJ68190.1 - 0.84 8.6 3.9 1.7 7.6 2.7 1.4 1 0 0 1 1 1 0 LIM-domain binding protein AP2 PF00847.15 CDJ68191.1 - 4.6e-11 42.7 4.8 1.2e-10 41.3 3.3 1.7 1 0 0 1 1 1 1 AP2 domain SR-25 PF10500.4 CDJ68192.1 - 0.0016 17.9 1.2 0.0016 17.9 0.8 2.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein 2OG-FeII_Oxy_2 PF13532.1 CDJ68193.1 - 0.0024 17.7 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Acyl-CoA_dh_1 PF00441.19 CDJ68195.1 - 2e-14 53.9 4.3 2.9e-14 53.4 3.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CDJ68195.1 - 2e-12 47.7 0.1 6.4e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CDJ68195.1 - 6.3e-11 41.6 0.1 4.1e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CDJ68195.1 - 3.4e-08 33.8 7.3 5.7e-08 33.0 5.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M50 PF02163.17 CDJ68196.1 - 1.3e-05 24.2 16.1 0.0006 18.8 11.2 2.2 1 1 0 1 1 1 1 Peptidase family M50 eRF1_1 PF03463.10 CDJ68197.1 - 6.7e-26 90.4 0.0 1.2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 CDJ68197.1 - 2.1e-19 70.1 0.0 6e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 CDJ68197.1 - 3.8e-15 56.1 0.1 1.5e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 eRF1 domain 3 Polyketide_cyc2 PF10604.4 CDJ68197.1 - 0.071 13.2 0.2 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Host_attach PF10116.4 CDJ68197.1 - 7.6 6.7 11.2 3.4 7.9 0.1 3.5 4 0 0 4 4 4 0 Protein required for attachment to host cells rve PF00665.21 CDJ68199.1 - 1.9e-14 53.8 0.0 3.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain FtsJ PF01728.14 CDJ68202.1 - 3.7e-19 69.4 0.0 1.6e-17 64.0 0.0 2.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Topo_Zn_Ribbon PF08272.6 CDJ68202.1 - 0.057 12.7 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Methyltrans_Mon PF14314.1 CDJ68202.1 - 0.087 10.6 0.0 0.15 9.9 0.0 1.2 1 0 0 1 1 1 0 Virus-capping methyltransferase GSHPx PF00255.14 CDJ68203.1 - 1.3e-27 95.2 0.8 1.9e-27 94.7 0.5 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CDJ68203.1 - 1.4e-07 31.2 0.3 6.7e-07 29.0 0.2 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDJ68203.1 - 1.9e-05 24.2 0.0 0.00014 21.4 0.0 2.1 2 0 0 2 2 2 1 Redoxin SelP_N PF04592.9 CDJ68203.1 - 0.038 13.3 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Thioredoxin_8 PF13905.1 CDJ68203.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Ribosomal_60s PF00428.14 CDJ68203.1 - 1.4 9.3 13.6 3.4 8.1 9.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mito_carr PF00153.22 CDJ68204.1 - 1.1e-62 207.6 3.2 2.9e-22 78.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydrolase_like2 PF13246.1 CDJ68204.1 - 0.061 13.2 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit ketoacyl-synt PF00109.21 CDJ68205.1 - 2.2e-65 220.6 0.0 5.8e-65 219.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CDJ68205.1 - 1.1e-53 181.5 1.1 4.5e-53 179.6 0.2 2.4 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 CDJ68205.1 - 6e-42 143.3 3.5 8.2e-42 142.9 0.2 2.8 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 CDJ68205.1 - 4.9e-32 110.2 0.1 9.9e-32 109.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 CDJ68205.1 - 1.1e-29 103.1 0.0 3.1e-26 91.8 0.0 2.6 2 0 0 2 2 2 2 Male sterility protein PP-binding PF00550.20 CDJ68205.1 - 8.8e-12 45.1 0.2 2e-11 43.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CDJ68205.1 - 5.3e-08 32.5 0.2 0.00015 21.2 0.0 3.1 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CDJ68205.1 - 0.0034 16.3 0.0 0.19 10.5 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CDJ68205.1 - 0.011 15.7 1.5 4.2 7.3 0.2 2.7 2 0 0 2 2 2 0 NADH(P)-binding Syntaxin-6_N PF09177.6 CDJ68207.1 - 1.5e-15 57.3 9.7 5.9e-15 55.4 1.1 2.3 2 0 0 2 2 2 2 Syntaxin 6, N-terminal SNARE PF05739.14 CDJ68207.1 - 6.8e-07 28.8 8.4 6.8e-07 28.8 5.8 3.0 4 0 0 4 4 4 1 SNARE domain Peptidase_M61 PF05299.7 CDJ68207.1 - 0.0016 18.4 1.5 0.0056 16.6 0.3 2.2 2 1 1 3 3 3 1 M61 glycyl aminopeptidase Phage_fiber_2 PF03406.8 CDJ68207.1 - 0.017 14.7 1.2 0.041 13.5 0.8 1.6 1 0 0 1 1 1 0 Phage tail fibre repeat Minor_capsid_2 PF11114.3 CDJ68207.1 - 0.043 13.6 0.7 0.094 12.5 0.1 1.8 2 0 0 2 2 2 0 Minor capsid protein AAA_13 PF13166.1 CDJ68207.1 - 0.044 12.2 5.3 0.055 11.9 3.7 1.1 1 0 0 1 1 1 0 AAA domain Nup88 PF10168.4 CDJ68207.1 - 0.058 11.2 11.8 0.07 10.9 8.2 1.0 1 0 0 1 1 1 0 Nuclear pore component Cu-oxidase_4 PF02578.10 CDJ68207.1 - 0.065 12.3 1.4 0.11 11.5 0.3 1.7 1 1 1 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase ATG16 PF08614.6 CDJ68207.1 - 0.082 12.7 17.8 0.32 10.8 5.0 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Blt1 PF12754.2 CDJ68207.1 - 0.1 12.1 5.5 0.15 11.6 3.8 1.2 1 0 0 1 1 1 0 Cell-cycle control medial ring component BLOC1_2 PF10046.4 CDJ68207.1 - 0.33 11.1 0.2 0.33 11.1 0.1 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COMP PF11598.3 CDJ68207.1 - 1.2 9.2 6.1 0.61 10.2 1.5 2.5 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein TMPIT PF07851.8 CDJ68207.1 - 2.6 7.0 9.2 5.5 5.9 0.5 2.2 2 0 0 2 2 2 0 TMPIT-like protein cIII PF08134.6 CDJ68207.1 - 7 6.3 7.1 1 9.0 1.4 2.2 2 0 0 2 2 2 0 cIII protein family Ribosomal_L23 PF00276.15 CDJ68208.1 - 7.6e-13 48.2 0.2 1.7e-12 47.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CDJ68208.1 - 1.2e-07 31.6 20.9 3.9e-07 29.9 14.5 1.9 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain TusA PF01206.12 CDJ68208.1 - 0.0096 15.5 0.1 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Sulfurtransferase TusA Pro_isomerase PF00160.16 CDJ68209.1 - 5.5e-39 133.8 0.0 6.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spt20 PF12090.3 CDJ68210.1 - 0.014 14.7 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Spt20 family BAF1_ABF1 PF04684.8 CDJ68210.1 - 6.2 5.5 16.0 13 4.4 11.1 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 CDJ68211.1 - 1.4e-10 40.6 4.4 2.4e-06 27.2 0.1 4.5 4 1 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.27 CDJ68212.1 - 4.2e-29 99.3 5.3 5.7e-07 29.1 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CDJ68212.1 - 8.1e-05 20.9 1.2 0.033 12.3 0.0 2.6 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Ribosomal_60s PF00428.14 CDJ68212.1 - 0.018 15.4 3.6 0.018 15.4 2.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.4 CDJ68212.1 - 0.03 14.0 2.3 0.03 14.0 1.6 2.6 2 1 0 2 2 2 0 Anti-sigma-K factor rskA TB2_DP1_HVA22 PF03134.14 CDJ68213.1 - 0.055 13.2 0.3 0.069 12.8 0.2 1.2 1 0 0 1 1 1 0 TB2/DP1, HVA22 family UMPH-1 PF05822.7 CDJ68214.1 - 0.14 11.4 1.2 0.18 11.1 0.8 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF1980 PF09323.5 CDJ68214.1 - 0.2 11.3 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Ant_C PF05586.6 CDJ68214.1 - 0.23 11.9 3.8 4.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Anthrax receptor C-terminus region PGA_cap PF09587.5 CDJ68214.1 - 0.65 9.3 3.1 0.75 9.0 2.2 1.0 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Pex14_N PF04695.8 CDJ68214.1 - 0.91 9.5 13.8 0.14 12.2 0.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAB3GAP2_N PF14655.1 CDJ68214.1 - 1.3 7.9 14.5 0.91 8.4 1.1 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus G0-G1_switch_2 PF15103.1 CDJ68214.1 - 1.8 8.8 10.3 0.36 11.0 0.8 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF4446 PF14584.1 CDJ68214.1 - 2.1 8.1 6.7 12 5.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) FKBP_N PF01346.13 CDJ68214.1 - 3.2 7.8 23.0 0.26 11.3 3.5 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase EIIBC-GUT_N PF03612.9 CDJ68214.1 - 4.4 6.8 7.6 1 8.9 0.4 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2361 PF10153.4 CDJ68214.1 - 5.7 7.1 15.5 3.3 7.9 3.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) DUF1840 PF08895.6 CDJ68214.1 - 5.7 7.0 13.1 1.3 9.1 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Iron_permease PF04120.7 CDJ68214.1 - 6.5 6.3 9.9 7.6 6.1 0.6 2.2 2 0 0 2 2 2 0 Low affinity iron permease DUF4131 PF13567.1 CDJ68215.1 - 0.013 14.8 0.2 0.031 13.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Gly-zipper_OmpA PF13436.1 CDJ68215.1 - 0.013 15.1 0.7 0.013 15.1 0.5 5.2 3 1 1 4 4 4 0 Glycine-zipper containing OmpA-like membrane domain CDC27 PF09507.5 CDJ68217.1 - 0.06 12.5 5.2 0.067 12.4 3.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF155 PF02582.9 CDJ68217.1 - 0.15 11.9 0.6 0.43 10.4 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 Med13_N PF11597.3 CDJ68217.1 - 0.33 9.5 8.9 0.57 8.8 6.1 1.4 1 1 0 1 1 1 0 Mediator complex subunit 13 N-terminal zf-CCCH PF00642.19 CDJ68218.1 - 2.1e-07 30.4 10.3 1.1e-05 25.0 0.8 2.9 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) adh_short PF00106.20 CDJ68220.1 - 6e-18 65.3 0.3 6e-18 65.3 0.2 1.7 2 0 0 2 2 1 1 short chain dehydrogenase KR PF08659.5 CDJ68220.1 - 3.9e-10 39.6 0.2 3.9e-10 39.6 0.1 1.8 2 1 0 2 2 1 1 KR domain adh_short_C2 PF13561.1 CDJ68220.1 - 6e-06 26.2 0.1 9.5e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Adeno_hexon PF01065.14 CDJ68220.1 - 0.0032 16.4 0.9 0.0039 16.1 0.6 1.2 1 0 0 1 1 1 1 Hexon, adenovirus major coat protein, N-terminal domain CBP4 PF07960.6 CDJ68220.1 - 0.0075 15.8 9.3 0.013 15.0 6.4 1.4 1 0 0 1 1 1 1 CBP4 Epimerase PF01370.16 CDJ68220.1 - 0.13 11.6 0.1 2.3 7.5 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF2255 PF10012.4 CDJ68220.1 - 0.15 11.9 2.7 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) DUF3533 PF12051.3 CDJ68220.1 - 0.26 9.9 3.6 0.37 9.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Med15 PF09606.5 CDJ68220.1 - 0.57 8.3 31.0 0.74 7.9 21.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DOR PF14839.1 CDJ68220.1 - 1.6 8.4 12.7 2.7 7.6 8.8 1.4 1 0 0 1 1 1 0 DOR family LCD1 PF09798.4 CDJ68220.1 - 2 6.2 15.3 2.8 5.8 10.6 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4355 PF14265.1 CDJ68220.1 - 4.2 7.3 19.7 5.8 6.8 9.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF4557 PF15101.1 CDJ68220.1 - 5.6 6.7 13.2 10 5.9 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SprA-related PF12118.3 CDJ68220.1 - 7.7 5.7 18.6 11 5.2 12.9 1.2 1 0 0 1 1 1 0 SprA-related family SR-25 PF10500.4 CDJ68221.1 - 0.0054 16.2 21.3 0.0054 16.2 14.8 9.3 6 2 3 9 9 9 2 Nuclear RNA-splicing-associated protein Androgen_recep PF02166.11 CDJ68222.1 - 0.011 14.6 10.2 0.011 14.6 7.1 2.0 1 1 1 2 2 1 0 Androgen receptor Serinc PF03348.10 CDJ68222.1 - 0.15 10.7 3.5 0.21 10.2 2.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Lin-8 PF03353.10 CDJ68222.1 - 1.4 8.1 7.1 1.8 7.7 4.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2973 PF11189.3 CDJ68222.1 - 1.9 8.2 5.6 5.4 6.8 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2973) G-alpha PF00503.15 CDJ68222.1 - 2.1 6.9 4.9 2.7 6.5 3.4 1.1 1 0 0 1 1 1 0 G-protein alpha subunit dsDNA_bind PF01984.15 CDJ68222.1 - 2.3 8.2 24.5 0.24 11.3 4.6 2.2 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DUF788 PF05620.6 CDJ68222.1 - 4.4 7.1 7.9 4 7.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) CDK2AP PF09806.4 CDJ68222.1 - 4.9 7.3 18.0 6.9 6.8 12.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3484 PF11983.3 CDJ68222.1 - 6.3 7.7 14.4 9.6 7.1 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) PNRC PF15365.1 CDJ68222.1 - 6.3 6.8 7.1 7.1 6.7 0.8 2.5 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator FimP PF09766.4 CDJ68222.1 - 6.5 5.7 15.2 3.1 6.7 0.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein ATAD4 PF15321.1 CDJ68222.1 - 7 7.7 8.6 18 6.4 1.0 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 PAT1 PF09770.4 CDJ68222.1 - 9.7 4.2 26.3 11 4.0 18.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GBP_C PF02841.9 CDJ68223.1 - 0.096 11.8 20.2 0.14 11.3 14.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.14 CDJ68223.1 - 0.13 10.0 2.7 0.15 9.8 1.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.13 CDJ68223.1 - 0.15 11.8 5.1 0.22 11.3 3.5 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF812 PF05667.6 CDJ68223.1 - 0.2 10.1 16.8 0.28 9.6 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2052 PF09747.4 CDJ68223.1 - 0.2 11.5 8.8 0.3 10.9 6.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Phage_GPO PF05929.6 CDJ68223.1 - 0.35 10.0 16.5 0.47 9.6 11.4 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.4 CDJ68223.1 - 0.6 8.9 15.0 0.75 8.6 10.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 CDJ68223.1 - 0.64 7.2 20.1 0.77 7.0 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF572 PF04502.8 CDJ68223.1 - 0.71 9.0 14.3 0.77 8.9 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Fmp27_WPPW PF10359.4 CDJ68223.1 - 0.82 8.0 5.3 0.95 7.7 3.7 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.1 CDJ68223.1 - 1.4 7.2 15.1 1.6 7.0 10.4 1.2 1 0 0 1 1 1 0 AAA domain FemAB PF02388.11 CDJ68223.1 - 3 6.4 13.5 4 6.0 9.4 1.2 1 0 0 1 1 1 0 FemAB family DUF4557 PF15101.1 CDJ68223.1 - 3.2 7.5 12.3 4.7 6.9 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_23 PF13476.1 CDJ68223.1 - 3.4 7.9 6.9 4.6 7.4 4.8 1.2 1 0 0 1 1 1 0 AAA domain DUF966 PF06136.8 CDJ68223.1 - 3.6 6.9 7.0 4 6.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mnd1 PF03962.10 CDJ68223.1 - 3.8 7.1 16.3 5.1 6.7 11.3 1.3 1 0 0 1 1 1 0 Mnd1 family AATF-Che1 PF13339.1 CDJ68223.1 - 4 7.6 16.7 2.9 8.0 9.9 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor APG6 PF04111.7 CDJ68223.1 - 4.9 6.1 15.1 5.8 5.8 10.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3373 PF11853.3 CDJ68223.1 - 5.5 5.4 10.9 8.2 4.8 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) IncA PF04156.9 CDJ68223.1 - 5.6 6.5 17.0 4.8 6.7 10.4 1.7 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 CDJ68223.1 - 5.9 5.4 9.9 7 5.2 6.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SOBP PF15279.1 CDJ68223.1 - 6 7.1 8.2 7.6 6.8 5.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RHD3 PF05879.7 CDJ68223.1 - 6.8 4.4 8.7 8.5 4.1 6.0 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Effector_1 PF04518.7 CDJ68223.1 - 7.5 5.4 17.0 12 4.7 11.8 1.3 1 0 0 1 1 1 0 Effector from type III secretion system DUF2413 PF10310.4 CDJ68223.1 - 8 5.1 35.1 3.9 6.1 22.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2413) Shadoo PF14999.1 CDJ68224.1 - 0.019 14.8 11.1 0.035 13.9 7.7 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF4460 PF14687.1 CDJ68224.1 - 0.036 13.8 10.2 0.048 13.4 2.9 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4460) 7tm_1 PF00001.16 CDJ68224.1 - 0.12 11.5 0.5 0.22 10.6 0.3 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Serinc PF03348.10 CDJ68224.1 - 0.17 10.5 4.5 0.3 9.7 3.1 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.4 CDJ68224.1 - 2.1 6.4 38.8 3.6 5.7 26.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TGS PF02824.16 CDJ68225.1 - 1.4e-21 76.0 0.0 2.9e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CDJ68225.1 - 1e-18 67.3 0.0 2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDJ68225.1 - 1.3e-11 44.0 0.1 6.1e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CDJ68225.1 - 8.2e-05 22.4 0.2 0.5 10.1 0.2 2.5 1 1 0 2 2 2 2 Dynamin family ArgK PF03308.11 CDJ68225.1 - 0.00048 18.9 0.3 0.0022 16.8 0.1 2.0 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 CDJ68225.1 - 0.0088 16.5 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CDJ68225.1 - 0.033 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.22 CDJ68225.1 - 0.047 13.1 0.3 8.7 5.7 0.0 2.9 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 CDJ68225.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CDJ68225.1 - 0.17 12.7 0.8 0.68 10.7 0.6 2.3 1 1 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDJ68226.1 - 0.0013 18.2 17.4 0.012 15.0 3.1 3.3 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 CDJ68226.1 - 0.023 15.0 2.1 0.48 10.7 0.3 2.4 2 0 0 2 2 2 0 Dehydrin DHC_N2 PF08393.8 CDJ68227.1 - 2.1e-09 36.4 0.0 3.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDJ68227.1 - 9.1e-07 28.6 0.1 1.4e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CDJ68228.1 - 4.2e-22 78.2 0.0 9.4e-22 77.0 0.0 1.4 1 1 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 HisKA_3 PF07730.8 CDJ68228.1 - 0.0052 17.1 1.9 0.18 12.1 0.0 3.6 2 2 2 4 4 4 1 Histidine kinase Alkyl_sulf_C PF14864.1 CDJ68228.1 - 0.017 15.0 0.2 0.21 11.5 0.0 2.5 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal GntR PF00392.16 CDJ68228.1 - 0.051 13.0 0.6 6.4 6.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family NAD_binding_3 PF03447.11 CDJ68228.1 - 0.073 13.4 0.1 5 7.5 0.1 2.4 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Gasdermin PF04598.7 CDJ68228.1 - 0.082 11.6 6.7 0.16 10.6 4.0 1.9 1 1 1 2 2 2 0 Gasdermin family Baculo_PEP_C PF04513.7 CDJ68228.1 - 0.11 12.3 6.8 0.085 12.6 0.2 2.8 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 CDJ68228.1 - 0.12 11.8 4.8 0.04 13.4 1.2 1.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain SlyX PF04102.7 CDJ68228.1 - 0.6 10.5 3.3 0.91 9.9 0.6 2.5 2 0 0 2 2 2 0 SlyX Adeno_PIX PF03955.9 CDJ68228.1 - 1.5 9.4 4.4 5.2 7.6 0.3 3.0 2 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) Trypan_glycop PF00913.14 CDJ68229.1 - 0.0012 17.7 11.2 0.0015 17.4 7.8 1.0 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein (A-type) Activator_LAG-3 PF11498.3 CDJ68229.1 - 0.031 13.0 10.6 0.031 13.0 7.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDJ68229.1 - 0.036 12.2 11.1 0.037 12.2 7.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal POP1 PF06978.6 CDJ68229.1 - 0.044 13.4 4.3 0.051 13.2 3.0 1.0 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 FCP1_C PF09309.5 CDJ68229.1 - 0.06 12.6 1.8 0.068 12.4 1.2 1.2 1 0 0 1 1 1 0 FCP1, C-terminal BRF1 PF07741.8 CDJ68229.1 - 0.08 13.1 5.6 0.1 12.8 3.9 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Ctr PF04145.10 CDJ68229.1 - 0.15 12.1 1.1 0.17 11.9 0.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family RAB3GAP2_N PF14655.1 CDJ68229.1 - 0.18 10.7 2.0 0.18 10.7 1.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3138 PF11336.3 CDJ68229.1 - 0.19 9.8 12.1 0.22 9.6 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ldh_1_C PF02866.13 CDJ68229.1 - 0.21 11.3 1.0 0.24 11.1 0.7 1.1 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain SpaB_C PF14028.1 CDJ68229.1 - 0.35 10.3 10.9 0.42 10.1 7.6 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain PHD_3 PF13922.1 CDJ68229.1 - 0.44 10.8 2.9 0.66 10.2 2.0 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF4557 PF15101.1 CDJ68229.1 - 0.46 10.2 3.7 0.47 10.2 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FdhE PF04216.7 CDJ68229.1 - 0.73 9.4 8.8 0.77 9.4 6.1 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation NifQ PF04891.7 CDJ68229.1 - 0.96 9.5 4.4 1.2 9.3 3.0 1.1 1 0 0 1 1 1 0 NifQ IncA PF04156.9 CDJ68230.1 - 4.9e-05 23.0 8.1 4.9e-05 23.0 5.6 3.4 3 1 0 3 3 3 1 IncA protein Claudin_2 PF13903.1 CDJ68231.1 - 5.1 6.7 13.8 7.9 6.1 9.5 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction MecA PF05389.7 CDJ68232.1 - 0.078 12.5 0.8 0.097 12.1 0.5 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF1043 PF06295.7 CDJ68232.1 - 0.29 10.7 2.5 0.45 10.1 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Spc7 PF08317.6 CDJ68232.1 - 0.38 9.3 8.0 0.45 9.1 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MAM1 PF10434.4 CDJ68232.1 - 0.54 9.4 3.4 0.68 9.0 2.4 1.0 1 0 0 1 1 1 0 Monopolin complex protein MAM1 DUF3509 PF12021.3 CDJ68232.1 - 0.7 9.6 5.0 1.1 8.9 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3509) MxiH PF09392.5 CDJ68232.1 - 0.95 10.0 7.7 1.5 9.4 5.3 1.4 1 0 0 1 1 1 0 Type III secretion needle MxiH like Ras PF00071.17 CDJ68233.1 - 7.7e-61 204.1 0.1 9.7e-61 203.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ68233.1 - 9.1e-20 71.3 0.0 1.2e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDJ68233.1 - 2e-13 49.9 0.0 2.6e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CDJ68233.1 - 3.8e-06 26.8 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CDJ68233.1 - 3.1e-05 23.4 0.0 5.3e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CDJ68233.1 - 0.00027 20.1 0.0 0.00037 19.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CDJ68233.1 - 0.0026 17.8 0.0 0.0069 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CDJ68233.1 - 0.0039 17.1 0.0 0.0097 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDJ68233.1 - 0.007 15.5 0.1 0.02 14.1 0.0 1.8 1 1 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 CDJ68233.1 - 0.068 12.3 0.0 0.096 11.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CDJ68233.1 - 0.091 12.7 0.1 0.23 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CDJ68233.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Herpes_UL4 PF03277.8 CDJ68236.1 - 0.1 11.8 2.2 0.29 10.3 0.2 2.6 2 1 1 3 3 3 0 Herpesvirus UL4 family DUF1685 PF07939.6 CDJ68236.1 - 0.66 9.6 3.6 0.6 9.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) Suf PF05843.9 CDJ68236.1 - 4.3 6.9 11.3 0.31 10.7 1.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) UQ_con PF00179.21 CDJ68237.1 - 4.9e-28 97.3 0.0 7e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDJ68237.1 - 0.047 13.5 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 CDJ68237.1 - 0.064 12.9 0.7 0.67 9.6 0.5 2.0 1 1 0 1 1 1 0 UEV domain Chorion_2 PF03964.10 CDJ68237.1 - 8.7 6.9 17.9 20 5.8 0.5 2.4 2 0 0 2 2 2 0 Chorion family 2 ACDC PF14733.1 CDJ68238.1 - 1.1e-09 38.2 0.0 2.2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal SR-25 PF10500.4 CDJ68238.1 - 0.0081 15.6 8.5 0.0081 15.6 5.9 3.8 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein Gp58 PF07902.6 CDJ68238.1 - 8.5 4.4 9.2 11 4.0 6.4 1.1 1 0 0 1 1 1 0 gp58-like protein Apt1 PF10351.4 CDJ68238.1 - 9 5.0 7.3 4.4 6.0 0.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain CPSF_A PF03178.10 CDJ68239.1 - 1.9e-81 273.6 0.0 3.2e-81 272.9 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CDJ68239.1 - 5.9e-58 196.2 0.0 3.5e-54 183.8 0.0 2.1 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Peptidase_S24 PF00717.18 CDJ68240.1 - 3.6e-06 26.5 0.0 5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Tmemb_14 PF03647.8 CDJ68240.1 - 0.015 15.6 1.6 0.12 12.8 0.4 2.2 2 0 0 2 2 2 0 Transmembrane proteins 14C APG5 PF04106.7 CDJ68241.1 - 0.11 11.9 1.7 0.25 10.8 1.2 1.6 1 0 0 1 1 1 0 Autophagy protein Apg5 DUF342 PF03961.8 CDJ68241.1 - 4.2 5.6 2.5 9 4.5 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DDE_Tnp_ISL3 PF01610.12 CDJ68241.1 - 7.7 6.0 6.2 13 5.2 3.3 1.9 1 1 1 2 2 2 0 Transposase CS PF04969.11 CDJ68242.1 - 3.1e-17 62.9 0.0 5.3e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 CDJ68242.1 - 1.2e-15 57.2 0.7 1.2e-15 57.2 0.5 1.7 2 0 0 2 2 2 1 N-terminal conserved domain of Nudc. Hid1 PF12722.2 CDJ68242.1 - 3.3 5.2 11.4 5.5 4.5 7.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3987 PF13148.1 CDJ68242.1 - 4.8 5.6 9.7 17 3.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Muted PF14942.1 CDJ68242.1 - 5 6.9 19.5 14 5.5 8.6 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Metal_resist PF13801.1 CDJ68242.1 - 6.3 6.7 11.9 0.55 10.2 0.6 2.3 2 0 0 2 2 2 0 Heavy-metal resistance M_domain PF12938.2 CDJ68243.1 - 0.07 12.9 2.2 0.15 11.8 1.5 1.5 1 0 0 1 1 1 0 M domain of GW182 BLOC1_2 PF10046.4 CDJ68243.1 - 0.18 11.9 8.2 0.87 9.7 0.2 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Neur_chan_memb PF02932.11 CDJ68244.1 - 6.3 6.6 6.6 28 4.5 4.6 2.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.27 CDJ68245.1 - 1.4e-20 70.9 0.3 6.7e-07 28.1 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CDJ68245.1 - 2.8e-19 68.9 0.1 5.5e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDJ68245.1 - 2.1e-17 61.3 0.9 6.4e-06 25.6 0.0 3.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CDJ68245.1 - 8.5e-14 50.9 0.5 1e-05 25.0 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CDJ68245.1 - 2.9e-13 48.4 0.4 2.9e-06 26.3 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 CDJ68245.1 - 0.00024 20.8 0.1 0.76 9.5 0.0 2.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CDJ68245.1 - 0.00065 19.5 0.1 0.0082 16.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CDJ68245.1 - 0.0025 17.8 0.0 0.0058 16.6 0.0 1.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 CDJ68245.1 - 0.004 16.7 0.0 0.2 11.2 0.0 2.3 2 1 1 3 3 3 1 Caleosin related protein PB1 PF00564.19 CDJ68245.1 - 0.092 12.4 0.1 0.77 9.4 0.0 2.3 1 1 1 2 2 2 0 PB1 domain EF-hand_10 PF14788.1 CDJ68245.1 - 0.093 12.4 0.4 0.94 9.1 0.0 2.4 2 1 1 3 3 3 0 EF hand MHCassoc_trimer PF08831.5 CDJ68245.1 - 0.11 12.3 0.5 1.9 8.3 0.2 2.3 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Myb_DNA-binding PF00249.26 CDJ68248.1 - 1.4e-08 34.6 0.2 2.8e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDJ68248.1 - 2.9e-06 27.3 1.6 4.2e-06 26.7 0.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Fasciclin PF02469.17 CDJ68249.1 - 8.5e-07 29.0 0.0 2.2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Notch PF00066.12 CDJ68252.1 - 2.6e-51 171.6 105.0 1.6e-09 37.8 8.7 6.5 5 1 1 6 6 6 6 LNR domain Mog1 PF04603.7 CDJ68253.1 - 8.7e-23 80.8 0.1 1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein GvpO PF05800.6 CDJ68253.1 - 0.064 13.1 0.2 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO ANAPC15 PF15243.1 CDJ68254.1 - 0.3 11.1 5.7 0.36 10.9 4.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Lbh PF15317.1 CDJ68254.1 - 1.7 8.9 6.6 2.4 8.4 4.6 1.6 1 1 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein ubiquitin PF00240.18 CDJ68255.1 - 3.9e-11 42.1 0.1 1e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CDJ68255.1 - 0.00081 19.0 0.5 0.0023 17.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 CDJ68255.1 - 0.0027 18.2 0.0 0.058 13.9 0.0 2.3 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD IMCp PF12314.3 CDJ68256.1 - 1.4e-06 28.3 52.5 2.5e-06 27.5 14.6 3.6 2 1 2 4 4 4 3 Inner membrane complex protein PEP-utilizers_C PF02896.13 CDJ68256.1 - 0.057 12.2 0.0 3 6.6 0.0 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, TIM barrel domain VPS11_C PF12451.3 CDJ68257.1 - 1.2e-07 31.4 0.0 2.8e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 CDJ68257.1 - 0.0028 17.2 0.2 0.01 15.4 0.1 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS PHD PF00628.24 CDJ68257.1 - 0.0046 16.6 0.3 0.016 14.8 0.2 2.0 1 0 0 1 1 1 1 PHD-finger zf-C3HC4 PF00097.20 CDJ68257.1 - 0.029 14.0 2.3 0.14 11.8 1.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ68257.1 - 0.15 11.9 7.5 0.079 12.8 2.8 2.5 2 1 0 2 2 2 0 Ring finger domain SF-assemblin PF06705.6 CDJ68257.1 - 0.35 9.9 1.3 0.47 9.5 0.1 1.7 2 0 0 2 2 2 0 SF-assemblin/beta giardin zf-RING_5 PF14634.1 CDJ68257.1 - 6.3 6.6 10.0 0.25 11.1 2.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain gag-asp_proteas PF13975.1 CDJ68258.1 - 0.0032 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDJ68258.1 - 0.026 15.0 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.22 CDJ68259.1 - 1.6e-07 30.8 0.0 3.3e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L24e PF01246.15 CDJ68260.1 - 1.1e-19 69.9 0.9 1.1e-19 69.9 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2849 PF11011.3 CDJ68260.1 - 0.076 13.2 0.3 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) APO_RNA-bind PF05634.6 CDJ68260.1 - 0.28 10.3 11.1 0.19 10.8 6.6 1.6 1 1 1 2 2 2 0 APO RNA-binding BolA PF01722.13 CDJ68261.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 BolA-like protein Co_AT_N PF12557.3 CDJ68261.1 - 1.1 9.2 3.7 1.6 8.6 2.6 1.3 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Trigger_C PF05698.9 CDJ68262.1 - 2.7e-16 59.8 9.6 7.4e-16 58.4 6.6 1.7 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus Methyltransf_26 PF13659.1 CDJ68263.1 - 2.8e-08 33.8 0.0 5.8e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CDJ68263.1 - 0.00021 20.8 0.1 0.00088 18.8 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 CDJ68263.1 - 0.013 14.9 0.1 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 DNA methylase Pam16 PF03656.8 CDJ68264.1 - 1.7e-11 43.9 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Pam16 ALMS_motif PF15309.1 CDJ68265.1 - 0.33 10.8 6.7 0.39 10.5 4.6 1.1 1 0 0 1 1 1 0 ALMS motif Prenyltrans PF00432.16 CDJ68266.1 - 2.2e-36 123.0 23.7 1e-12 47.3 0.7 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CDJ68266.1 - 5.5e-16 58.9 0.2 1.6e-08 34.9 0.0 3.4 1 1 1 3 3 3 3 Prenyltransferase-like Actin PF00022.14 CDJ68267.1 - 2.2e-76 256.8 0.0 5.3e-69 232.5 0.0 2.1 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CDJ68267.1 - 0.0045 15.6 0.0 0.069 11.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein SMC_N PF02463.14 CDJ68268.1 - 1e-08 34.7 0.1 1e-08 34.7 0.1 2.5 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain DUF4363 PF14276.1 CDJ68268.1 - 0.018 14.7 0.4 0.018 14.7 0.3 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4363) Cas_DxTHG PF09455.5 CDJ68268.1 - 0.049 12.7 1.3 0.12 11.4 0.9 1.6 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family AAA_23 PF13476.1 CDJ68268.1 - 0.17 12.1 42.7 1.2e+02 2.8 16.8 4.6 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 CDJ68268.1 - 0.18 11.7 0.1 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 CDJ68269.1 - 7.4e-15 54.7 0.1 8.9e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDJ68269.1 - 6.2e-09 36.2 0.0 6.9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 CDJ68269.1 - 1.4e-07 31.2 0.2 3.2e-07 30.1 0.1 1.7 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CDJ68269.1 - 6.7e-05 22.1 0.0 8.9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 CDJ68269.1 - 0.001 19.3 1.0 0.0032 17.7 0.1 2.1 2 1 0 2 2 2 1 ABC transporter tRNA-synt_2d PF01409.15 CDJ68270.1 - 5e-19 68.4 0.0 3.7e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CDJ68270.1 - 3.6e-18 65.5 0.0 3.6e-18 65.5 0.0 3.3 3 0 0 3 3 3 1 Ferredoxin-fold anticodon binding domain Peptidase_M16 PF00675.15 CDJ68270.1 - 5.6e-18 65.1 0.1 5.6e-18 65.1 0.0 6.8 8 0 0 8 8 8 1 Insulinase (Peptidase family M16) SR-25 PF10500.4 CDJ68270.1 - 0.0013 18.2 3.2 0.0013 18.2 2.2 17.4 12 5 3 15 15 15 2 Nuclear RNA-splicing-associated protein DUF2690 PF10901.3 CDJ68271.1 - 0.062 13.3 0.4 0.067 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) DUF853 PF05872.7 CDJ68271.1 - 0.076 11.3 6.2 0.083 11.2 4.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF912 PF06024.7 CDJ68271.1 - 0.17 11.9 2.1 0.17 11.9 1.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AIF_C PF14721.1 CDJ68271.1 - 0.23 11.6 4.2 0.23 11.6 2.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FimP PF09766.4 CDJ68271.1 - 0.26 10.2 16.6 0.26 10.3 11.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein Baculo_PP31 PF05311.6 CDJ68271.1 - 0.28 10.4 8.6 0.27 10.4 6.0 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Rpp20 PF12328.3 CDJ68271.1 - 0.31 10.6 4.4 0.37 10.4 3.1 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P UBN2_3 PF14244.1 CDJ68271.1 - 0.43 10.1 9.9 0.43 10.1 6.9 1.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Peroxin-13_N PF04088.8 CDJ68271.1 - 0.59 10.0 4.3 0.71 9.8 3.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Suf PF05843.9 CDJ68271.1 - 0.78 9.4 12.9 0.74 9.4 8.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4647 PF15504.1 CDJ68271.1 - 0.79 8.5 13.1 0.78 8.5 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) RIC3 PF15361.1 CDJ68271.1 - 0.92 9.7 7.8 0.96 9.6 5.4 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF808 PF05661.7 CDJ68271.1 - 0.96 8.2 2.6 1.1 8.0 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Spt20 PF12090.3 CDJ68271.1 - 1 8.7 10.9 1.2 8.4 7.6 1.3 1 0 0 1 1 1 0 Spt20 family G0-G1_switch_2 PF15103.1 CDJ68271.1 - 1.1 9.4 5.2 1.3 9.2 3.6 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 U1snRNP70_N PF12220.3 CDJ68271.1 - 1.3 9.3 13.2 1.8 8.9 9.2 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hus1 PF04005.7 CDJ68271.1 - 1.4 7.7 7.8 1.7 7.4 5.4 1.0 1 0 0 1 1 1 0 Hus1-like protein SprA-related PF12118.3 CDJ68271.1 - 2 7.6 21.7 2 7.6 15.0 1.0 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.4 CDJ68271.1 - 2 6.5 22.1 1.9 6.6 15.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Trypan_glycop_C PF10659.4 CDJ68271.1 - 2.9 8.2 11.0 3.3 8.0 7.6 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain DUF4557 PF15101.1 CDJ68271.1 - 2.9 7.6 17.1 2.8 7.7 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ctr PF04145.10 CDJ68271.1 - 3.4 7.6 5.2 3.7 7.5 3.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Serinc PF03348.10 CDJ68271.1 - 3.5 6.2 8.3 3.4 6.2 5.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.12 CDJ68271.1 - 3.6 7.3 8.4 3.3 7.4 5.8 1.0 1 0 0 1 1 1 0 DDHD domain EIIBC-GUT_N PF03612.9 CDJ68271.1 - 3.7 7.1 5.8 3.5 7.2 4.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3154 PF11351.3 CDJ68271.1 - 3.7 7.3 7.7 4.2 7.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) Band_3_cyto PF07565.8 CDJ68271.1 - 3.9 6.9 8.4 3.6 7.0 5.8 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain HNOBA PF07701.9 CDJ68271.1 - 3.9 6.6 9.1 4.6 6.3 6.3 1.0 1 0 0 1 1 1 0 Heme NO binding associated OATP PF03137.15 CDJ68271.1 - 4.1 5.3 5.9 4 5.3 4.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.5 CDJ68271.1 - 4.7 6.9 8.3 5.1 6.8 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Anoctamin PF04547.7 CDJ68271.1 - 5.6 5.4 8.5 5.7 5.4 5.9 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2347 PF09804.4 CDJ68271.1 - 6.1 6.0 6.6 6.1 6.0 4.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF3464 PF11947.3 CDJ68271.1 - 9.2 5.7 8.0 10 5.5 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) SR-25 PF10500.4 CDJ68272.1 - 3.1e-05 23.5 3.0 3.5e-05 23.3 2.1 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TcdB_toxin_midN PF12256.3 CDJ68272.1 - 0.095 12.1 1.5 0.15 11.4 1.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF243 PF03103.12 CDJ68272.1 - 0.49 10.5 5.3 0.13 12.4 1.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF243) DUF3526 PF12040.3 CDJ68272.1 - 1.9 8.6 10.8 4.6 7.3 7.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3526) Activator_LAG-3 PF11498.3 CDJ68272.1 - 4.9 5.7 23.9 1.9 7.1 9.7 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PHD_3 PF13922.1 CDJ68272.1 - 8.5 6.6 8.9 0.72 10.1 1.7 2.1 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Claudin_2 PF13903.1 CDJ68273.1 - 3.5e-05 23.5 2.7 3.5e-05 23.5 1.9 3.8 3 1 1 4 4 4 1 PMP-22/EMP/MP20/Claudin tight junction DUF966 PF06136.8 CDJ68273.1 - 0.074 12.4 25.6 0.85 8.9 3.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF966) Plasmodium_Vir PF05795.6 CDJ68273.1 - 0.18 10.9 2.9 1.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein FimP PF09766.4 CDJ68273.1 - 1.2 8.0 39.5 0.3 10.1 6.4 3.1 3 0 0 3 3 3 0 Fms-interacting protein DUF1645 PF07816.6 CDJ68274.1 - 0.0068 16.8 5.8 0.0068 16.8 4.0 11.2 8 3 3 11 11 11 2 Protein of unknown function (DUF1645) DER1 PF04511.10 CDJ68276.1 - 1.8e-11 43.8 0.0 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Der1-like family Med3 PF11593.3 CDJ68276.1 - 0.83 8.8 9.5 1.4 8.1 6.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDC27 PF09507.5 CDJ68278.1 - 0.096 11.8 39.6 0.18 11.0 27.4 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1510 PF07423.6 CDJ68278.1 - 3.1 7.1 42.9 5.3 6.3 29.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 CDJ68278.1 - 4.3 6.7 33.9 6.5 6.2 23.5 1.2 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.1 CDJ68278.1 - 5.3 5.4 38.9 7.2 5.0 27.0 1.2 1 0 0 1 1 1 0 Raftlin Actin PF00022.14 CDJ68279.1 - 1.8e-06 26.6 0.0 0.073 11.4 0.0 3.2 3 1 0 3 3 3 3 Actin Med15 PF09606.5 CDJ68279.1 - 0.24 9.5 10.8 0.3 9.2 7.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LIME1 PF15332.1 CDJ68282.1 - 0.00026 20.3 4.8 0.00029 20.1 2.4 1.7 1 1 0 1 1 1 1 Lck-interacting transmembrane adapter 1 Activator_LAG-3 PF11498.3 CDJ68282.1 - 1.4 7.6 71.2 0.04 12.6 29.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PPARgamma_N PF12577.3 CDJ68282.1 - 7.9 6.8 6.3 29 5.0 0.6 2.4 2 0 0 2 2 2 0 PPAR gamma N-terminal region DREPP PF05558.7 CDJ68283.1 - 0.62 9.8 19.9 0.75 9.6 13.8 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF2339 PF10101.4 CDJ68283.1 - 0.95 7.6 12.6 1 7.5 8.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) WD40 PF00400.27 CDJ68284.1 - 2.3e-15 55.7 13.0 9.1e-06 25.3 0.1 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Spt20 PF12090.3 CDJ68284.1 - 0.0052 16.1 2.4 0.14 11.4 0.1 2.3 2 0 0 2 2 2 2 Spt20 family BBS2_Mid PF14783.1 CDJ68284.1 - 0.098 12.4 0.0 9.5 6.0 0.0 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 CDJ68284.1 - 0.4 10.3 0.0 0.74 9.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A DUF572 PF04502.8 CDJ68285.1 - 0.16 11.1 21.7 0.18 10.9 15.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 CDJ68285.1 - 4.6 4.7 13.8 5.9 4.4 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 CDJ68285.1 - 6.9 6.5 10.2 9.1 6.1 7.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.8 CDJ68285.1 - 9.2 6.0 21.3 11 5.7 14.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Brr6_like_C_C PF10104.4 CDJ68286.1 - 1.4e-19 69.9 0.0 4.2e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Neur_chan_memb PF02932.11 CDJ68286.1 - 0.0057 16.5 3.1 0.54 10.0 0.2 2.5 2 1 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region APC_CDC26 PF10471.4 CDJ68286.1 - 0.045 14.5 1.3 0.045 14.5 0.9 5.6 5 0 0 5 5 5 0 Anaphase-promoting complex APC subunit 1 PAP2 PF01569.16 CDJ68286.1 - 6.6 6.4 12.1 2.2 7.9 3.8 3.1 2 1 0 2 2 2 0 PAP2 superfamily Sua5_yciO_yrdC PF01300.13 CDJ68287.1 - 8.7e-14 51.1 2.5 7.4e-12 44.8 0.0 3.0 3 0 0 3 3 3 2 Telomere recombination SUA5 PF03481.8 CDJ68287.1 - 6e-08 32.8 2.3 1.4e-07 31.6 0.4 2.5 1 1 1 2 2 2 1 Putative GTP-binding controlling metal-binding SR-25 PF10500.4 CDJ68287.1 - 7.9e-05 22.2 4.6 7.9e-05 22.2 3.2 6.0 5 1 1 6 6 6 2 Nuclear RNA-splicing-associated protein Apt1 PF10351.4 CDJ68287.1 - 0.31 9.8 11.6 1.2 7.9 0.6 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Spt20 PF12090.3 CDJ68287.1 - 0.77 9.0 5.8 0.92 8.8 0.2 2.3 2 0 0 2 2 2 0 Spt20 family F-box-like PF12937.2 CDJ68288.1 - 4.5e-06 26.2 0.1 9.2e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CDJ68288.1 - 0.0073 15.9 2.4 0.029 14.0 0.0 2.5 2 0 0 2 2 2 1 F-box domain Ribosomal_S9 PF00380.14 CDJ68291.1 - 7.1e-37 126.3 0.4 7.1e-37 126.3 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 PAT1 PF09770.4 CDJ68291.1 - 3.9 5.6 25.0 5.3 5.1 17.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAT1 PF09770.4 CDJ68292.1 - 0.063 11.5 29.5 0.09 11.0 20.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDJ68292.1 - 0.88 7.1 24.9 1.4 6.5 17.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF605 PF04652.11 CDJ68292.1 - 1.3 8.3 45.1 1.6 8.0 31.2 1.1 1 0 0 1 1 1 0 Vta1 like SOBP PF15279.1 CDJ68292.1 - 1.6 9.0 36.7 2.3 8.5 25.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.8 CDJ68292.1 - 1.8 6.6 25.5 2.1 6.3 17.6 1.1 1 0 0 1 1 1 0 Utp14 protein RVT_1 PF00078.22 CDJ68293.1 - 0.026 13.8 0.0 0.056 12.7 0.0 1.6 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_MCEL PF03291.11 CDJ68294.1 - 6.5e-15 54.8 0.0 1.5e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 CDJ68294.1 - 0.00018 21.8 0.1 0.00059 20.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ68294.1 - 0.00066 20.1 0.0 0.0021 18.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ68294.1 - 0.029 14.9 0.5 0.083 13.4 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ68294.1 - 0.034 14.5 0.2 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ68294.1 - 0.065 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3396 PF11876.3 CDJ68294.1 - 0.068 12.2 0.4 0.25 10.4 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3396) SR-25 PF10500.4 CDJ68294.1 - 1.6 8.1 13.4 3.4 7.0 9.3 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM91_C PF14648.1 CDJ68295.1 - 0.1 11.4 0.1 0.1 11.4 0.1 2.4 1 1 0 2 2 2 0 FAM91 C-terminus DUF4139 PF13598.1 CDJ68296.1 - 5.1 6.3 7.7 8.1 5.6 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) DUF3306 PF11748.3 CDJ68296.1 - 5.6 7.6 9.2 39 4.9 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) T_Ag_DNA_bind PF02217.11 CDJ68297.1 - 0.0051 17.1 0.3 0.014 15.8 0.2 1.8 1 0 0 1 1 1 1 Origin of replication binding protein CBM_15 PF03426.9 CDJ68297.1 - 0.11 11.8 6.3 0.2 10.9 4.4 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Ligase_CoA PF00549.14 CDJ68297.1 - 2.8 7.5 10.4 4.7 6.8 1.8 2.9 3 0 0 3 3 3 0 CoA-ligase SR-25 PF10500.4 CDJ68298.1 - 2.4 7.5 64.2 0.059 12.8 6.1 3.8 2 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ68298.1 - 5.9 6.2 30.6 1.8 7.8 3.0 3.5 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0160 PF03690.8 CDJ68299.1 - 2e-39 135.8 0.0 6e-21 75.1 0.0 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0160) Ribosomal_60s PF00428.14 CDJ68299.1 - 0.012 15.9 13.5 0.012 15.9 9.3 4.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein RAB3GAP2_N PF14655.1 CDJ68299.1 - 0.023 13.7 1.3 0.031 13.3 0.9 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3123 PF11321.3 CDJ68299.1 - 0.68 10.2 3.9 2 8.7 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF2722 PF10846.3 CDJ68299.1 - 3.8 6.4 10.6 5.5 5.9 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) IncA PF04156.9 CDJ68300.1 - 2.3e-05 24.1 9.8 2.3e-05 24.1 6.8 2.5 3 1 0 3 3 3 1 IncA protein DUF4401 PF14351.1 CDJ68300.1 - 0.051 12.5 9.7 0.078 11.9 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF2232 PF09991.4 CDJ68300.1 - 0.28 10.1 4.4 0.69 8.8 3.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Peptidase_C37 PF05416.7 CDJ68300.1 - 0.92 7.7 9.2 1.1 7.4 6.4 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase LCD1 PF09798.4 CDJ68300.1 - 1.9 6.3 8.3 3 5.7 5.8 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF572 PF04502.8 CDJ68300.1 - 2.2 7.4 19.1 0.94 8.6 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) PAT1 PF09770.4 CDJ68300.1 - 3.5 5.7 22.6 4.5 5.3 15.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pap_E4 PF02711.9 CDJ68300.1 - 3.6 8.4 19.3 6.7 7.5 0.0 3.2 2 1 1 3 3 3 0 E4 protein DivIC PF04977.10 CDJ68300.1 - 9.4 5.8 8.8 21 4.6 6.1 1.5 1 0 0 1 1 1 0 Septum formation initiator LRR_4 PF12799.2 CDJ68301.1 - 3.8e-08 32.7 13.1 0.16 11.6 0.8 5.6 4 2 0 4 4 4 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.1 CDJ68301.1 - 4.3e-08 33.2 0.0 1.4e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 CDJ68301.1 - 2.1e-05 24.1 0.4 0.00055 19.5 0.1 2.2 2 0 0 2 2 2 1 CAP-Gly domain SAPS PF04499.10 CDJ68301.1 - 3.5e-05 22.6 8.1 6.2e-05 21.8 5.6 1.4 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein LRR_8 PF13855.1 CDJ68301.1 - 0.00037 20.1 13.0 0.0084 15.8 0.1 4.4 4 1 0 4 4 4 2 Leucine rich repeat DUF2722 PF10846.3 CDJ68301.1 - 0.011 14.7 0.6 0.011 14.7 0.4 4.6 3 1 2 5 5 1 0 Protein of unknown function (DUF2722) LRR_1 PF00560.28 CDJ68301.1 - 0.039 13.9 11.2 5.7 7.3 0.3 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 CDJ68301.1 - 0.16 12.3 11.0 41 5.0 0.1 5.9 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CDJ68301.1 - 0.44 10.7 13.2 17 5.8 0.2 5.7 6 0 0 6 6 5 0 Leucine Rich repeat Band_3_cyto PF07565.8 CDJ68301.1 - 1.6 8.2 30.2 0.62 9.5 0.8 2.7 3 0 0 3 3 3 0 Band 3 cytoplasmic domain DUF2052 PF09747.4 CDJ68301.1 - 3.2 7.6 42.0 0.69 9.8 0.6 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.9 CDJ68301.1 - 4.6 6.7 19.3 2.1 7.8 8.8 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF572 PF04502.8 CDJ68301.1 - 4.9 6.2 32.2 0.11 11.6 16.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) GAGA_bind PF06217.7 CDJ68301.1 - 8.1 6.3 26.5 2.1 8.2 11.2 2.5 2 0 0 2 2 2 0 GAGA binding protein-like family RNA_pol_Rpb1_5 PF04998.12 CDJ68301.1 - 9 5.4 12.0 12 5.0 6.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 DUF1614 PF07758.6 CDJ68302.1 - 0.028 14.1 0.6 0.028 14.1 0.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1614) PAT1 PF09770.4 CDJ68302.1 - 0.069 11.3 40.6 0.08 11.1 28.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP-synt_E PF05680.7 CDJ68302.1 - 0.41 10.6 14.7 2.6 8.0 2.2 2.5 2 0 0 2 2 2 0 ATP synthase E chain Spt20 PF12090.3 CDJ68302.1 - 2.3 7.5 11.0 6.5 6.0 0.3 2.1 2 0 0 2 2 2 0 Spt20 family DUF4557 PF15101.1 CDJ68302.1 - 5.3 6.8 21.4 3.8 7.3 6.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) SR-25 PF10500.4 CDJ68303.1 - 1.4e-06 27.9 20.4 1.4e-06 27.9 14.1 12.1 8 3 5 14 14 14 5 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ68303.1 - 6.6e-05 22.9 21.8 6.6e-05 22.9 15.1 14.4 12 3 3 15 15 15 4 Domain of unknown function (DUF755) Cwf_Cwc_15 PF04889.7 CDJ68303.1 - 0.0027 17.4 7.6 0.0027 17.4 5.3 8.8 6 2 2 8 8 8 1 Cwf15/Cwc15 cell cycle control protein FimP PF09766.4 CDJ68303.1 - 0.0032 16.5 6.8 0.0032 16.5 4.7 8.4 6 4 1 7 7 7 1 Fms-interacting protein MFS_2 PF13347.1 CDJ68303.1 - 2.6 6.3 7.4 0.12 10.7 0.8 1.9 3 0 0 3 3 3 0 MFS/sugar transport protein 7TM_GPCR_Srv PF10323.4 CDJ68303.1 - 5.9 5.9 7.1 0.51 9.4 0.0 2.7 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srv Ribosomal_60s PF00428.14 CDJ68304.1 - 0.015 15.7 13.3 0.047 14.0 9.2 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein TMEM171 PF15471.1 CDJ68304.1 - 4 6.1 8.4 1.3 7.7 3.4 1.7 1 1 1 2 2 2 0 Transmembrane protein family 171 YqzE PF14038.1 CDJ68305.1 - 0.12 12.1 0.7 0.21 11.3 0.5 1.3 1 0 0 1 1 1 0 YqzE-like protein CHCH PF06747.8 CDJ68305.1 - 1 9.3 8.0 5.4 7.0 0.2 3.1 2 1 1 3 3 3 0 CHCH domain Pex14_N PF04695.8 CDJ68306.1 - 2.1 8.3 18.0 1.5 8.8 5.2 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Afaf PF15339.1 CDJ68306.1 - 5.7 6.4 7.9 0.22 11.1 1.3 1.7 2 0 0 2 2 2 0 Acrosome formation-associated factor DUF2370 PF10176.4 CDJ68306.1 - 6.7 5.9 8.8 0.33 10.2 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) stn_TNFRSF12A PF12191.3 CDJ68307.1 - 0.0064 16.5 2.7 0.0096 15.9 1.8 1.3 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Crust_neuro_H PF03858.8 CDJ68307.1 - 0.039 14.5 0.2 0.093 13.3 0.1 1.7 1 0 0 1 1 1 0 Crustacean neurohormone H DUF2782 PF11191.3 CDJ68307.1 - 0.94 9.4 3.0 8.5 6.4 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2782) XRN_N PF03159.13 CDJ68308.1 - 1.3e-67 227.6 0.0 2e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Glutaredoxin PF00462.19 CDJ68309.1 - 0.0078 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin YicC_N PF03755.8 CDJ68310.1 - 0.4 10.6 2.7 0.22 11.4 0.3 1.6 2 0 0 2 2 2 0 YicC-like family, N-terminal region IcmL PF11393.3 CDJ68313.1 - 0.021 14.7 0.1 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Macrophage killing protein with similarity to conjugation protein EF-hand_7 PF13499.1 CDJ68314.1 - 3.6e-16 59.0 0.0 3.5e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDJ68314.1 - 3.8e-15 53.9 0.0 0.0029 16.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CDJ68314.1 - 3.9e-13 48.0 0.0 0.003 17.3 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CDJ68314.1 - 1.1e-09 37.1 0.0 0.049 12.9 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CDJ68314.1 - 3.7e-07 29.6 0.4 0.11 12.1 0.0 3.7 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CDJ68314.1 - 6.7e-07 29.1 0.0 0.0023 17.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain VIT1 PF01988.14 CDJ68315.1 - 2.8e-55 187.1 0.7 4e-55 186.6 0.5 1.2 1 0 0 1 1 1 1 VIT family DUF599 PF04654.7 CDJ68315.1 - 0.0031 16.7 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF599 SNF PF00209.13 CDJ68316.1 - 1.3e-18 66.8 32.4 1.3e-18 66.8 22.5 2.1 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family WES_acyltransf PF03007.11 CDJ68318.1 - 0.02 14.4 1.5 0.063 12.8 0.0 2.6 3 1 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Glutaredoxin PF00462.19 CDJ68319.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF3357 PF11837.3 CDJ68319.1 - 0.088 12.6 0.1 0.98 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Ku_PK_bind PF08785.6 CDJ68320.1 - 1.4e-17 63.6 0.2 2.7e-07 30.4 0.0 3.5 2 1 0 2 2 2 2 Ku C terminal domain like Ku PF02735.11 CDJ68320.1 - 6.5e-14 51.8 0.0 1.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CDJ68320.1 - 8.8e-08 31.8 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Asp PF00026.18 CDJ68321.1 - 1.7e-09 37.3 0.0 0.00011 21.5 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 CDJ68321.1 - 3.4e-08 33.1 0.1 0.0042 16.6 0.0 4.2 4 1 0 4 4 4 2 Xylanase inhibitor C-terminal TAXi_N PF14543.1 CDJ68321.1 - 3.9e-05 23.6 2.6 3.9e-05 23.6 1.8 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal RRM_6 PF14259.1 CDJ68322.1 - 0.02 14.8 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ68323.1 - 1.6e-09 37.5 0.0 0.076 12.9 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ68323.1 - 2e-08 33.7 0.0 0.29 10.7 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ68323.1 - 2.1e-07 30.6 0.2 0.00068 19.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S9 PF00326.16 CDJ68324.1 - 4.2e-14 52.2 4.1 1.3e-05 24.4 0.2 3.8 2 1 1 3 3 3 3 Prolyl oligopeptidase family SR-25 PF10500.4 CDJ68325.1 - 0.00084 18.8 16.3 0.00084 18.8 11.3 3.0 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein RAP1 PF07218.6 CDJ68325.1 - 7.6 4.4 5.0 11 3.9 3.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DCP2 PF05026.8 CDJ68327.1 - 9.7e-17 60.6 1.5 2.6e-16 59.2 1.0 1.8 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CDJ68327.1 - 3.6e-13 49.3 0.0 8.1e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain LsmAD PF06741.8 CDJ68327.1 - 4.6 7.4 9.2 0.092 12.8 0.2 3.0 2 1 1 3 3 3 0 LsmAD domain DUF912 PF06024.7 CDJ68328.1 - 3.4 7.7 4.6 21 5.2 0.8 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pyridox_ox_2 PF12900.2 CDJ68329.1 - 0.037 13.8 0.3 0.037 13.8 0.2 2.7 4 0 0 4 4 4 0 Pyridoxamine 5'-phosphate oxidase ABC_tran PF00005.22 CDJ68330.1 - 5.7e-33 114.1 0.1 1e-16 61.4 0.0 3.2 4 0 0 4 4 2 2 ABC transporter AAA_29 PF13555.1 CDJ68330.1 - 1.2e-09 37.5 0.2 0.0012 18.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CDJ68330.1 - 5.5e-09 36.8 0.1 0.00095 19.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_membrane PF00664.18 CDJ68330.1 - 1.1e-07 31.5 4.4 4.3e-07 29.6 0.6 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region MMR_HSR1 PF01926.18 CDJ68330.1 - 1.1e-06 28.5 0.3 0.014 15.3 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CDJ68330.1 - 2.1e-06 27.6 0.0 0.031 13.9 0.0 3.3 3 0 0 3 3 3 1 Archaeal ATPase AAA_21 PF13304.1 CDJ68330.1 - 5.9e-06 26.4 0.5 0.013 15.4 0.1 3.2 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 CDJ68330.1 - 7.9e-06 25.9 0.1 7.9e-06 25.9 0.1 5.2 4 2 0 4 4 2 1 AAA ATPase domain Miro PF08477.8 CDJ68330.1 - 1.1e-05 25.9 0.2 0.12 12.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CDJ68330.1 - 1.1e-05 25.5 5.3 0.0054 16.8 0.0 3.9 4 1 0 4 4 2 2 AAA domain T2SE PF00437.15 CDJ68330.1 - 1.6e-05 23.9 0.1 0.059 12.2 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 CDJ68330.1 - 2.2e-05 24.7 3.4 0.08 13.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CDJ68330.1 - 3.5e-05 23.2 1.9 0.057 12.8 0.2 2.9 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CDJ68330.1 - 4.6e-05 23.1 0.0 0.084 12.5 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 CDJ68330.1 - 5.3e-05 22.9 0.1 0.023 14.4 0.0 2.6 2 0 0 2 2 2 1 NTPase RNA12 PF10443.4 CDJ68330.1 - 0.00012 20.7 0.0 0.00012 20.7 0.0 2.3 3 0 0 3 3 2 1 RNA12 protein Zeta_toxin PF06414.7 CDJ68330.1 - 0.00016 20.8 0.7 0.018 14.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 CDJ68330.1 - 0.0003 20.3 0.1 0.47 9.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.7 CDJ68330.1 - 0.00039 20.1 3.4 0.26 10.9 0.0 3.2 3 0 0 3 3 3 2 NACHT domain DUF258 PF03193.11 CDJ68330.1 - 0.00039 19.6 1.7 0.72 9.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 cobW PF02492.14 CDJ68330.1 - 0.00043 19.7 0.7 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_60s PF00428.14 CDJ68330.1 - 0.00064 20.0 6.7 0.00064 20.0 4.6 9.8 8 1 1 9 9 7 1 60s Acidic ribosomal protein Mg_chelatase PF01078.16 CDJ68330.1 - 0.00077 18.6 0.2 1.3 8.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 CDJ68330.1 - 0.00078 19.8 29.5 0.032 14.5 0.0 4.5 5 0 0 5 5 4 2 AAA domain ArgK PF03308.11 CDJ68330.1 - 0.0012 17.6 7.6 0.054 12.2 0.0 2.7 3 0 0 3 3 2 2 ArgK protein Viral_helicase1 PF01443.13 CDJ68330.1 - 0.0014 18.1 0.3 0.088 12.3 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SMC_N PF02463.14 CDJ68330.1 - 0.0014 17.8 0.0 0.62 9.2 0.0 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CDJ68330.1 - 0.0018 17.7 2.4 0.51 9.7 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 CDJ68330.1 - 0.0035 17.2 0.1 0.69 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 CDJ68330.1 - 0.0037 16.1 0.2 3 6.6 0.1 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 CDJ68330.1 - 0.0039 17.0 13.3 0.0097 15.7 0.0 4.6 5 0 0 5 5 5 1 AAA domain ATP_bind_1 PF03029.12 CDJ68330.1 - 0.0043 16.6 0.1 0.89 9.0 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF815 PF05673.8 CDJ68330.1 - 0.0045 15.9 0.2 0.15 10.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 CDJ68330.1 - 0.0048 15.9 0.0 0.41 9.5 0.0 3.5 3 1 0 3 3 3 1 KAP family P-loop domain DEAD PF00270.24 CDJ68330.1 - 0.0054 16.2 0.6 1.3 8.5 0.1 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase UPF0079 PF02367.12 CDJ68330.1 - 0.0077 15.8 0.6 0.46 10.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 CDJ68330.1 - 0.012 15.3 3.1 0.27 10.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CDJ68330.1 - 0.017 15.2 0.9 1.4 9.1 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_11 PF13086.1 CDJ68330.1 - 0.026 14.1 9.7 1.2 8.5 4.5 3.5 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CDJ68330.1 - 0.029 13.0 0.0 0.61 8.6 0.0 2.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF87 PF01935.12 CDJ68330.1 - 0.033 14.0 0.5 0.32 10.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Spt20 PF12090.3 CDJ68330.1 - 0.043 13.1 9.1 0.89 8.8 0.5 2.6 2 0 0 2 2 2 0 Spt20 family AAA PF00004.24 CDJ68330.1 - 0.044 13.9 0.1 0.044 13.9 0.1 3.7 5 0 0 5 5 2 0 ATPase family associated with various cellular activities (AAA) PsbH PF00737.15 CDJ68330.1 - 0.061 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein PduV-EutP PF10662.4 CDJ68330.1 - 0.084 12.3 0.5 2.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RAB3GAP2_N PF14655.1 CDJ68330.1 - 0.096 11.6 14.1 0.071 12.1 1.1 2.7 3 0 0 3 3 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1943 PF09172.6 CDJ68330.1 - 0.13 11.1 2.2 0.34 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Herpes_Helicase PF02689.9 CDJ68330.1 - 1.5 6.4 2.1 3.8 5.1 0.5 2.0 2 0 0 2 2 2 0 Helicase DUF2075 PF09848.4 CDJ68330.1 - 4.7 6.0 10.3 0.62 8.9 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 CDJ68331.1 - 1.4e-33 115.9 0.0 3.4e-33 114.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CDJ68331.1 - 4.4e-07 29.9 0.0 4.1e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CDJ68331.1 - 3.7e-06 27.0 0.1 9.2e-05 22.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CDJ68331.1 - 4.1e-06 26.9 0.3 0.0013 18.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CDJ68331.1 - 9e-06 24.8 0.0 2.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CDJ68331.1 - 1.1e-05 25.1 0.1 0.00026 20.7 0.1 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CDJ68331.1 - 0.00034 20.0 0.0 0.00077 18.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CDJ68331.1 - 0.00096 17.9 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 CDJ68331.1 - 0.0012 18.4 0.0 0.0045 16.4 0.0 2.0 2 1 0 2 2 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CDJ68331.1 - 0.0016 18.6 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 CDJ68331.1 - 0.0018 18.1 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDJ68331.1 - 0.0021 17.2 0.0 0.0043 16.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 CDJ68331.1 - 0.0024 17.6 0.1 0.0077 15.9 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain Mg_chelatase PF01078.16 CDJ68331.1 - 0.0024 17.0 0.0 0.0048 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CDJ68331.1 - 0.0025 17.7 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CDJ68331.1 - 0.004 16.5 0.1 0.022 14.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CDJ68331.1 - 0.0046 17.7 0.2 0.017 15.9 0.0 2.1 3 0 0 3 3 1 1 AAA domain AAA_3 PF07726.6 CDJ68331.1 - 0.0054 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CDJ68331.1 - 0.0055 15.6 0.0 0.0089 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 CDJ68331.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.1 CDJ68331.1 - 0.0076 16.5 0.1 0.048 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CDJ68331.1 - 0.008 16.1 0.1 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CDJ68331.1 - 0.01 15.4 0.1 0.021 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CDJ68331.1 - 0.015 15.2 0.0 0.042 13.8 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CDJ68331.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 CDJ68331.1 - 0.023 14.2 0.2 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 CDJ68331.1 - 0.025 14.4 0.2 0.42 10.4 0.0 2.6 2 1 0 2 2 2 0 Shikimate kinase KaiC PF06745.8 CDJ68331.1 - 0.028 13.5 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC UPF0079 PF02367.12 CDJ68331.1 - 0.029 13.9 0.3 0.058 13.0 0.0 1.6 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CDJ68331.1 - 0.042 13.5 0.3 0.37 10.4 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 CDJ68331.1 - 0.053 13.1 0.0 0.15 11.7 0.0 1.8 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 CDJ68331.1 - 0.087 13.1 0.3 0.57 10.4 0.0 2.3 2 2 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 CDJ68331.1 - 0.1 12.9 2.0 10 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain UMP1 PF05348.6 CDJ68332.1 - 2.5e-10 40.3 0.0 4.4e-10 39.6 0.0 1.3 2 0 0 2 2 2 1 Proteasome maturation factor UMP1 Metal_resist PF13801.1 CDJ68332.1 - 0.071 13.0 4.4 0.11 12.4 3.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Shadoo PF14999.1 CDJ68333.1 - 0.011 15.5 17.1 0.013 15.3 5.6 2.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Aldedh PF00171.17 CDJ68333.1 - 0.034 12.4 20.1 0.013 13.8 0.2 4.0 3 2 1 4 4 4 0 Aldehyde dehydrogenase family Ribosomal_60s PF00428.14 CDJ68333.1 - 2.6 8.5 32.7 0.076 13.4 1.3 3.7 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF2057 PF09829.4 CDJ68334.1 - 0.19 11.3 1.9 0.24 11.0 1.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3597 PF12200.3 CDJ68334.1 - 0.88 9.9 3.7 1 9.7 2.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Med3 PF11593.3 CDJ68334.1 - 3.8 6.6 5.7 3.8 6.6 3.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hexapep PF00132.19 CDJ68335.1 - 2.2e-06 26.8 3.2 6.1e-05 22.3 0.2 2.1 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Spt20 PF12090.3 CDJ68335.1 - 0.0045 16.3 1.6 0.0045 16.3 1.1 1.1 1 0 0 1 1 1 1 Spt20 family RAB3GAP2_N PF14655.1 CDJ68335.1 - 0.0053 15.8 1.6 0.0053 15.8 1.1 1.0 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus EphA2_TM PF14575.1 CDJ68335.1 - 0.026 14.9 0.2 0.61 10.5 0.6 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FAD_oxidored PF12831.2 CDJ68335.1 - 0.041 12.9 4.2 0.049 12.7 2.9 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase OATP PF03137.15 CDJ68335.1 - 0.11 10.5 0.4 0.13 10.2 0.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Hexapep_2 PF14602.1 CDJ68335.1 - 0.24 11.0 0.3 0.24 11.0 0.2 1.8 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase RskA PF10099.4 CDJ68335.1 - 0.85 9.3 10.1 1.4 8.5 7.0 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Chorion_2 PF03964.10 CDJ68335.1 - 4.4 7.9 12.5 0.24 11.9 4.7 1.9 2 0 0 2 2 2 0 Chorion family 2 Ribosomal_60s PF00428.14 CDJ68335.1 - 4.5 7.7 13.4 7.4 7.0 9.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ68336.1 - 0.0021 17.5 4.8 0.0021 17.5 3.3 4.4 4 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ68336.1 - 0.015 15.3 11.5 0.015 15.3 8.0 6.5 5 1 0 5 5 5 0 Domain of unknown function (DUF755) DUF605 PF04652.11 CDJ68337.1 - 1.2e-06 28.2 38.7 3.2e-06 26.8 15.2 2.2 2 0 0 2 2 2 2 Vta1 like SAGA-Tad1 PF12767.2 CDJ68337.1 - 0.00028 20.6 29.3 0.03 13.9 12.6 2.3 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit SPX PF03105.14 CDJ68337.1 - 0.0082 15.9 1.7 0.0082 15.9 1.2 2.2 2 0 0 2 2 2 1 SPX domain YqfQ PF14181.1 CDJ68337.1 - 0.015 15.3 9.6 0.015 15.3 6.6 4.6 4 2 1 5 5 3 0 YqfQ-like protein Tom37_C PF11801.3 CDJ68337.1 - 0.032 14.0 17.5 0.071 12.9 2.1 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain PrsW-protease PF13367.1 CDJ68337.1 - 0.23 10.6 5.8 1.2 8.2 2.0 2.3 2 0 0 2 2 2 0 Protease prsW family Raftlin PF15250.1 CDJ68337.1 - 0.35 9.3 22.6 0.11 10.9 6.2 2.1 2 0 0 2 2 2 0 Raftlin FLO_LFY PF01698.11 CDJ68337.1 - 0.4 9.4 23.4 0.087 11.6 4.8 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Band_3_cyto PF07565.8 CDJ68337.1 - 0.56 9.6 22.3 0.46 9.9 0.2 2.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain GPCR_chapero_1 PF11904.3 CDJ68337.1 - 0.73 8.9 15.5 0.61 9.1 4.1 2.4 2 0 0 2 2 2 0 GPCR-chaperone Zip PF02535.17 CDJ68337.1 - 1.1 8.1 16.3 0.28 10.1 7.4 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4011 PF13195.1 CDJ68337.1 - 1.8 8.5 13.5 5 7.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) TAF1D PF15333.1 CDJ68337.1 - 1.8 8.3 19.6 7.1 6.3 9.7 2.1 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Hid1 PF12722.2 CDJ68337.1 - 5.1 4.6 23.6 3 5.3 8.5 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein CAF-1_p150 PF11600.3 CDJ68337.1 - 6.2 6.1 41.1 1.8 7.8 17.3 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 CDJ68337.1 - 7.7 6.3 20.6 8.2 6.2 7.5 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_DNAp_acc PF04929.7 CDJ68337.1 - 9.3 5.1 29.1 1.1 8.1 11.4 2.3 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DUF1546 PF07571.8 CDJ68338.1 - 3.4e-07 30.2 0.3 1.4e-06 28.2 0.2 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Herpes_UL87 PF03043.9 CDJ68338.1 - 0.13 10.5 8.6 0.1 10.9 3.7 2.2 2 1 0 2 2 2 0 Herpesvirus UL87 family DUF1178 PF06676.6 CDJ68339.1 - 0.024 14.8 8.4 0.028 14.6 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) RIG-I_C-RD PF11648.3 CDJ68339.1 - 0.038 13.8 0.9 0.05 13.4 0.6 1.1 1 0 0 1 1 1 0 C-terminal domain of RIG-I Spt20 PF12090.3 CDJ68339.1 - 0.14 11.5 5.6 0.16 11.3 3.8 1.0 1 0 0 1 1 1 0 Spt20 family MRF_C2 PF13888.1 CDJ68339.1 - 0.38 10.5 4.8 0.48 10.2 3.3 1.1 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 FYDLN_acid PF09538.5 CDJ68339.1 - 0.41 11.2 3.5 0.54 10.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Serinc PF03348.10 CDJ68339.1 - 0.42 9.2 3.1 0.45 9.1 2.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2387 PF09526.5 CDJ68339.1 - 0.88 9.5 9.8 1.5 8.7 6.8 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Ribosomal_S27e PF01667.12 CDJ68339.1 - 1.3 8.5 4.7 0.59 9.7 0.5 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 Pex14_N PF04695.8 CDJ68339.1 - 1.5 8.8 9.0 2.1 8.3 6.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RanBP PF00641.13 CDJ68339.1 - 1.6 7.9 5.2 2.4 7.3 3.6 1.2 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Peptidase_U57 PF05582.7 CDJ68341.1 - 0.5 9.2 18.1 0.55 9.1 12.5 1.0 1 0 0 1 1 1 0 YabG peptidase U57 RNA_pol_Rpc4 PF05132.9 CDJ68341.1 - 1.5 8.8 18.4 1.7 8.6 12.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 YqfQ PF14181.1 CDJ68341.1 - 1.8 8.6 24.3 2 8.4 16.8 1.0 1 0 0 1 1 1 0 YqfQ-like protein Gti1_Pac2 PF09729.4 CDJ68341.1 - 2.1 8.1 16.0 2.3 8.0 11.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family AIF_C PF14721.1 CDJ68341.1 - 2.2 8.5 17.1 2.4 8.3 11.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CPSF100_C PF13299.1 CDJ68341.1 - 2.3 8.3 19.4 2.6 8.2 13.4 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FYDLN_acid PF09538.5 CDJ68341.1 - 3.7 8.1 11.1 4.4 7.9 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Tim54 PF11711.3 CDJ68341.1 - 3.9 5.9 15.0 4.2 5.8 10.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3449 PF11931.3 CDJ68341.1 - 4.2 6.8 20.9 4.6 6.7 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) PBP1_TM PF14812.1 CDJ68341.1 - 5.4 7.3 13.4 7.3 6.9 9.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NARP1 PF12569.3 CDJ68341.1 - 6.2 5.4 22.9 7 5.2 15.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM60A PF15396.1 CDJ68341.1 - 7 6.3 16.8 7.9 6.1 11.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDJ68341.1 - 7.6 6.2 21.0 8 6.1 14.6 1.0 1 0 0 1 1 1 0 DDHD domain DUF3306 PF11748.3 CDJ68341.1 - 8.2 7.1 19.9 11 6.6 13.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FLO_LFY PF01698.11 CDJ68341.1 - 9.2 4.9 21.1 9.4 4.9 14.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1764 PF08576.5 CDJ68341.1 - 9.5 7.0 24.7 14 6.5 17.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) NPR3 PF03666.8 CDJ68341.1 - 9.6 4.6 19.6 11 4.3 13.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pex24p PF06398.6 CDJ68343.1 - 0.052 12.3 1.0 0.072 11.8 0.7 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin YfhO PF09586.5 CDJ68343.1 - 0.26 9.2 0.3 0.45 8.4 0.2 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Trm112p PF03966.11 CDJ68344.1 - 1.5e-12 47.6 0.1 1.5e-12 47.6 0.1 2.4 2 0 0 2 2 2 1 Trm112p-like protein SR-25 PF10500.4 CDJ68344.1 - 3.4e-05 23.4 11.7 3.4e-05 23.4 8.1 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Spore_coat_CotO PF14153.1 CDJ68344.1 - 0.0021 17.5 10.4 0.0021 17.5 7.2 2.2 2 0 0 2 2 2 1 Spore coat protein CotO AAA_23 PF13476.1 CDJ68344.1 - 0.02 15.2 22.0 0.051 13.9 7.6 2.2 2 0 0 2 2 2 0 AAA domain DUF4557 PF15101.1 CDJ68344.1 - 0.073 12.9 31.8 0.52 10.1 3.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Activator_LAG-3 PF11498.3 CDJ68344.1 - 0.12 11.1 82.1 0.12 11.0 29.1 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 CAF-1_p150 PF11600.3 CDJ68344.1 - 0.14 11.4 24.8 0.01 15.2 9.9 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Presenilin PF01080.12 CDJ68344.1 - 0.54 9.0 5.8 0.94 8.2 4.1 1.4 1 0 0 1 1 1 0 Presenilin DUF4220 PF13968.1 CDJ68344.1 - 0.56 9.2 7.9 1 8.3 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Raftlin PF15250.1 CDJ68344.1 - 1.2 7.5 19.5 0.16 10.4 9.2 1.9 2 0 0 2 2 2 0 Raftlin Cellulose_synt PF03552.9 CDJ68344.1 - 2.3 6.4 5.6 3.1 5.9 3.9 1.2 1 0 0 1 1 1 0 Cellulose synthase Med15 PF09606.5 CDJ68344.1 - 3.7 5.6 82.8 0.61 8.2 32.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ68344.1 - 8.9 6.0 42.4 0.22 11.3 14.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF159 PF02586.9 CDJ68345.1 - 1.5e-29 102.9 0.0 1.5e-29 102.9 0.0 2.8 2 2 0 2 2 2 1 Uncharacterised ACR, COG2135 Na_trans_assoc PF06512.8 CDJ68345.1 - 0.41 10.5 28.3 0.99 9.3 6.0 2.5 2 0 0 2 2 2 0 Sodium ion transport-associated Ycf1 PF05758.7 CDJ68345.1 - 1.2 6.7 28.7 1.8 6.2 14.1 2.1 2 0 0 2 2 2 0 Ycf1 Otopetrin PF03189.8 CDJ68345.1 - 1.4 7.8 13.8 0.8 8.6 3.8 2.3 2 0 0 2 2 2 0 Otopetrin JAB PF01398.16 CDJ68346.1 - 1.8e-11 43.7 0.7 9.1e-10 38.2 0.0 2.8 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Oxysterol_BP PF01237.13 CDJ68346.1 - 0.77 8.1 3.1 1.2 7.5 2.1 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein PilM PF07419.7 CDJ68346.1 - 1.5 8.2 0.0 1.5 8.2 0.0 2.6 3 0 0 3 3 3 0 PilM UCH PF00443.24 CDJ68347.1 - 0.00014 21.0 0.0 0.00014 21.0 0.0 3.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase N6_N4_Mtase PF01555.13 CDJ68347.1 - 0.34 10.3 2.4 5.5 6.4 0.1 2.9 3 2 0 3 3 3 0 DNA methylase RAP1 PF07218.6 CDJ68347.1 - 0.55 8.2 2.6 0.79 7.7 1.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Gti1_Pac2 PF09729.4 CDJ68349.1 - 0.12 12.2 2.5 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family DUF966 PF06136.8 CDJ68349.1 - 0.34 10.2 10.2 0.07 12.5 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Spt20 PF12090.3 CDJ68349.1 - 1.8 7.8 18.3 3.9 6.7 7.7 2.2 2 0 0 2 2 2 0 Spt20 family HAUS6_N PF14661.1 CDJ68349.1 - 3 7.1 27.5 0.037 13.3 5.9 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Activator_LAG-3 PF11498.3 CDJ68349.1 - 5.4 5.6 59.1 2.1 6.9 13.3 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF1266 PF06889.6 CDJ68349.1 - 5.8 6.6 16.2 5.3 6.8 5.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Dala_Dala_lig_N PF01820.16 CDJ68349.1 - 6 7.2 11.0 6.1 7.1 0.6 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF4557 PF15101.1 CDJ68349.1 - 9.1 6.0 29.5 1.4 8.7 10.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) NUDIX PF00293.23 CDJ68350.1 - 0.0023 17.5 0.1 0.004 16.7 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain DUF3295 PF11702.3 CDJ68350.1 - 0.049 12.6 6.1 0.062 12.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF812 PF05667.6 CDJ68350.1 - 0.21 10.0 0.4 0.26 9.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4207 PF13904.1 CDJ68350.1 - 0.42 9.9 3.9 0.61 9.4 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Secretin_N_2 PF07655.8 CDJ68350.1 - 0.43 10.9 13.1 0.74 10.2 9.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain KAR9 PF08580.5 CDJ68350.1 - 1.8 6.7 7.4 2.5 6.2 5.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 BaffR-Tall_bind PF09256.5 CDJ68350.1 - 1.9 8.1 6.4 12 5.6 0.9 2.5 2 0 0 2 2 2 0 BAFF-R, TALL-1 binding Macoilin PF09726.4 CDJ68350.1 - 2 6.5 7.2 2.5 6.2 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Period_C PF12114.3 CDJ68350.1 - 2.9 7.4 12.4 3.2 7.3 7.1 1.9 2 0 0 2 2 2 0 Period protein 2/3C-terminal region SR-25 PF10500.4 CDJ68351.1 - 0.015 14.7 3.1 0.019 14.4 2.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IBN_N PF03810.14 CDJ68352.1 - 1.7e-12 47.0 0.2 2.9e-12 46.3 0.0 1.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain zf-CCCH PF00642.19 CDJ68353.1 - 1.6e-09 37.2 6.6 3.8e-09 35.9 4.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 CDJ68353.1 - 3.5e-05 23.4 9.1 0.0001 21.9 6.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDJ68353.1 - 0.00023 21.1 6.4 0.00023 21.1 4.4 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ68353.1 - 0.058 13.2 16.9 0.26 11.1 11.7 2.1 1 1 0 1 1 1 0 Ring finger domain zf-P11 PF03854.9 CDJ68353.1 - 0.84 9.1 7.9 0.072 12.5 1.5 2.0 2 0 0 2 2 2 0 P-11 zinc finger Ank_2 PF12796.2 CDJ68354.1 - 2.3e-27 95.1 11.6 1.5e-16 60.5 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ68354.1 - 2.6e-24 83.7 11.3 3.1e-08 33.0 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 CDJ68354.1 - 1.6e-19 68.0 2.6 7.7e-06 25.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CDJ68354.1 - 1.1e-15 57.5 1.8 1.3e-11 44.6 0.1 3.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDJ68354.1 - 2.7e-15 56.0 12.3 1.4e-08 34.6 0.4 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) AAA_28 PF13521.1 CDJ68354.1 - 0.12 12.3 0.1 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain TBCC PF07986.7 CDJ68355.1 - 6e-14 51.4 0.2 6e-14 51.4 0.1 1.9 2 0 0 2 2 2 1 Tubulin binding cofactor C SseC PF04888.7 CDJ68355.1 - 0.0064 15.8 16.9 0.0064 15.8 11.7 4.4 4 0 0 4 4 4 1 Secretion system effector C (SseC) like family zf-DHHC PF01529.15 CDJ68355.1 - 0.11 11.8 1.1 7.9 5.8 0.0 3.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase Dala_Dala_lig_N PF01820.16 CDJ68355.1 - 0.18 12.1 0.1 0.18 12.1 0.1 3.3 3 1 0 3 3 3 0 D-ala D-ala ligase N-terminus Pkinase PF00069.20 CDJ68357.1 - 1.3e-05 24.4 1.0 1.6e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain DUF2722 PF10846.3 CDJ68357.1 - 0.0032 16.5 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Fumble PF03630.9 CDJ68358.1 - 7.2e-66 222.3 0.0 2.1e-61 207.7 0.0 2.4 2 0 0 2 2 2 2 Fumble Coatomer_WDAD PF04053.9 CDJ68358.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Suf PF05843.9 CDJ68358.1 - 1.9 8.1 5.2 4.5 6.9 3.6 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cut8_M PF14483.1 CDJ68359.1 - 0.054 13.2 0.6 0.16 11.7 0.4 1.9 1 0 0 1 1 1 0 Cut8 dimerisation domain WD40 PF00400.27 CDJ68364.1 - 7.7e-10 38.2 0.9 0.052 13.4 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF874 PF05917.6 CDJ68365.1 - 0.0049 15.7 5.3 0.0055 15.6 3.7 1.1 1 0 0 1 1 1 1 Helicobacter pylori protein of unknown function (DUF874) Exonuc_VII_L PF02601.10 CDJ68365.1 - 0.015 14.4 7.6 0.016 14.4 5.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 CDJ68365.1 - 0.024 12.4 4.1 0.03 12.2 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAT1 PF09770.4 CDJ68365.1 - 0.13 10.4 24.3 0.13 10.4 16.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3585 PF12130.3 CDJ68365.1 - 0.24 11.2 19.8 0.35 10.7 13.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) DUF3552 PF12072.3 CDJ68365.1 - 0.51 9.5 17.9 0.8 8.8 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TFIIA PF03153.8 CDJ68365.1 - 0.53 10.1 16.2 0.66 9.8 11.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF106 PF01956.11 CDJ68365.1 - 0.55 9.7 5.6 0.94 8.9 3.9 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Med15 PF09606.5 CDJ68365.1 - 1 7.4 42.3 1.4 7.0 29.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TALPID3 PF15324.1 CDJ68365.1 - 2.2 5.5 15.7 2.8 5.1 10.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DUF342 PF03961.8 CDJ68365.1 - 3.9 5.7 10.9 5 5.4 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PAT1 PF09770.4 CDJ68366.1 - 6.3 4.9 14.7 6.6 4.8 10.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDJ68366.1 - 9 6.3 9.3 12 5.8 6.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region G-patch PF01585.18 CDJ68368.1 - 0.00014 21.6 3.1 0.00014 21.6 2.2 2.4 2 0 0 2 2 2 1 G-patch domain Methyltransf_18 PF12847.2 CDJ68369.1 - 1.2e-07 32.2 2.3 1.3e-07 32.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ68369.1 - 1.2e-06 28.5 0.1 1.2e-06 28.5 0.0 4.1 3 1 0 3 3 2 1 Methyltransferase domain PrmA PF06325.8 CDJ68369.1 - 3.9e-06 26.1 0.5 3.9e-06 26.1 0.4 2.5 3 0 0 3 3 2 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 CDJ68369.1 - 5e-06 26.0 0.5 5e-06 26.0 0.3 2.2 2 1 0 2 2 1 1 Conserved hypothetical protein 95 MTS PF05175.9 CDJ68369.1 - 5.3e-06 25.9 0.2 1.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CDJ68369.1 - 6e-06 26.0 1.8 1.6e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 CDJ68369.1 - 0.00031 20.4 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.4 CDJ68369.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 CDJ68369.1 - 0.026 13.6 0.1 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 CDJ68369.1 - 0.042 13.4 0.0 0.042 13.4 0.0 2.7 2 1 0 3 3 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ68369.1 - 0.055 13.9 0.4 0.41 11.1 0.3 2.5 1 1 0 1 1 1 0 Methyltransferase domain FimP PF09766.4 CDJ68369.1 - 0.055 12.5 22.9 0.095 11.7 8.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein DOT1 PF08123.8 CDJ68369.1 - 0.13 11.5 0.3 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Neur_chan_memb PF02932.11 CDJ68369.1 - 0.28 11.0 3.0 3 7.6 0.7 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.3 CDJ68369.1 - 0.83 8.9 13.2 2.4 7.4 0.4 2.5 2 0 0 2 2 2 0 Spt20 family Methyltransf_12 PF08242.7 CDJ68369.1 - 0.86 10.1 5.7 2.3 8.7 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain Suf PF05843.9 CDJ68369.1 - 2.8 7.6 20.2 5.5 6.6 7.2 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PRCC PF10253.4 CDJ68369.1 - 5.7 7.5 26.6 7.9 7.1 1.6 3.7 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Band_3_cyto PF07565.8 CDJ68369.1 - 6.5 6.1 16.1 3.9 6.9 0.2 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain zf-DHHC PF01529.15 CDJ68369.1 - 8.1 5.8 8.7 50 3.2 4.7 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase AAA_12 PF13087.1 CDJ68370.1 - 7.7e-28 97.2 0.1 1.7e-27 96.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Apt1 PF10351.4 CDJ68374.1 - 4.9 5.9 8.6 6.9 5.4 6.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAT1 PF09770.4 CDJ68375.1 - 0.16 10.1 12.0 0.16 10.2 8.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPT6_acidic PF14632.1 CDJ68376.1 - 8.2e-11 41.9 14.2 8.2e-11 41.9 9.9 6.6 3 2 2 5 5 5 1 Acidic N-terminal SPT6 DUF572 PF04502.8 CDJ68378.1 - 4.6e-28 98.3 20.7 4.6e-28 98.3 14.3 3.5 3 1 0 3 3 3 2 Family of unknown function (DUF572) Claudin_2 PF13903.1 CDJ68378.1 - 0.0087 15.7 14.0 0.099 12.3 2.0 3.8 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Atx10homo_assoc PF09759.4 CDJ68378.1 - 0.017 14.8 0.0 0.017 14.8 0.0 3.2 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain SpaB_C PF14028.1 CDJ68378.1 - 0.56 9.7 37.6 0.35 10.3 2.4 3.6 3 0 0 3 3 3 0 SpaB C-terminal domain Spt20 PF12090.3 CDJ68378.1 - 1.1 8.5 29.4 0.18 11.1 0.6 4.6 5 0 0 5 5 5 0 Spt20 family DUF2071 PF09844.4 CDJ68378.1 - 2.1 7.7 6.2 0.15 11.4 0.2 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (COG2071) Pkinase PF00069.20 CDJ68379.1 - 1.5e-71 240.5 0.0 2.1e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68379.1 - 3.8e-29 101.5 0.0 6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 CDJ68379.1 - 2.3e-14 53.2 0.0 3.5e-07 30.2 0.0 2.5 1 1 2 3 3 3 3 EF-hand domain pair CBM_20 PF00686.14 CDJ68379.1 - 2.3e-13 49.5 0.0 3.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain EF-hand_1 PF00036.27 CDJ68379.1 - 5.3e-10 37.8 0.0 0.009 15.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CDJ68379.1 - 2e-09 36.5 0.0 0.0014 18.3 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 CDJ68379.1 - 4.6e-07 29.3 0.0 0.0084 15.7 0.0 3.4 1 1 2 3 3 3 3 EF-hand domain pair Kdo PF06293.9 CDJ68379.1 - 0.00012 21.2 0.0 0.00026 20.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_5 PF13202.1 CDJ68379.1 - 0.00012 21.2 0.2 0.24 10.8 0.0 2.5 2 0 0 2 2 2 2 EF hand MDMPI_N PF11716.3 CDJ68379.1 - 0.018 15.4 7.5 0.054 13.9 5.2 1.9 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain APH PF01636.18 CDJ68379.1 - 0.04 13.6 2.0 0.19 11.4 1.4 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CDJ68379.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like BCAS3 PF12490.3 CDJ68379.1 - 0.24 10.6 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 TSP_1 PF00090.14 CDJ68381.1 - 0.0041 17.1 0.3 0.011 15.8 0.2 1.7 1 0 0 1 1 1 1 Thrombospondin type 1 domain Radial_spoke PF04712.7 CDJ68383.1 - 2.4e-07 29.9 0.0 3.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Radial spokehead-like protein F-box PF00646.28 CDJ68386.1 - 0.0003 20.3 0.2 0.00087 18.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain Rad50_zn_hook PF04423.9 CDJ68387.1 - 0.0057 16.0 1.2 0.01 15.3 0.8 1.4 1 0 0 1 1 1 1 Rad50 zinc hook motif Arm PF00514.18 CDJ68389.1 - 5.4e-08 32.3 2.6 0.0024 17.6 0.1 4.0 3 1 1 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDJ68389.1 - 1.1e-05 25.5 6.8 0.003 17.7 0.6 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 CDJ68389.1 - 0.00038 20.3 1.5 1.2 9.3 0.2 3.4 3 1 0 3 3 3 2 HEAT repeat Peptidase_M91 PF14891.1 CDJ68389.1 - 0.02 14.9 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 Effector protein HEAT_EZ PF13513.1 CDJ68389.1 - 0.84 10.2 8.6 73 4.0 5.0 3.5 1 1 1 2 2 2 0 HEAT-like repeat Robl_LC7 PF03259.12 CDJ68390.1 - 1.8e-05 24.2 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF2753 PF10952.3 CDJ68391.1 - 0.052 13.5 0.5 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) DUF4200 PF13863.1 CDJ68392.1 - 6.5e-12 45.4 6.1 6.5e-12 45.4 4.2 3.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4200) DUF1524 PF07510.6 CDJ68392.1 - 0.052 13.3 0.6 0.052 13.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) HSBP1 PF06825.7 CDJ68392.1 - 0.52 9.9 0.1 0.52 9.9 0.0 3.3 2 2 0 2 2 2 0 Heat shock factor binding protein 1 DUF3298 PF11738.3 CDJ68392.1 - 0.54 10.7 3.5 34 5.0 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3298) COG2 PF06148.6 CDJ68392.1 - 1.1 9.1 10.4 3.3 7.5 0.0 3.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 THDPS_N_2 PF14805.1 CDJ68392.1 - 1.8 8.4 6.8 0.24 11.2 0.5 2.6 2 1 1 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Med11 PF10280.4 CDJ68392.1 - 2.2 8.3 17.1 0.035 14.1 3.8 2.9 2 1 1 3 3 3 0 Mediator complex protein Borrelia_P83 PF05262.6 CDJ68392.1 - 8 4.6 23.6 9.9 4.3 16.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DivIC PF04977.10 CDJ68393.1 - 1.8e-05 24.1 0.6 2.7e-05 23.5 0.4 1.3 1 0 0 1 1 1 1 Septum formation initiator TMF_DNA_bd PF12329.3 CDJ68393.1 - 2.2e-05 24.1 0.8 3e-05 23.7 0.6 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 CDJ68393.1 - 0.00023 21.0 2.4 0.00034 20.5 1.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 CDJ68393.1 - 0.00024 20.7 10.1 0.00064 19.3 1.8 1.9 1 1 1 2 2 2 2 Homeobox associated leucine zipper ADIP PF11559.3 CDJ68393.1 - 0.00095 19.0 0.4 0.0015 18.4 0.3 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 CDJ68393.1 - 0.0013 18.2 0.4 0.0015 17.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF2730 PF10805.3 CDJ68393.1 - 0.0016 18.1 0.1 0.0018 17.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) bZIP_2 PF07716.10 CDJ68393.1 - 0.0028 17.4 4.2 0.0032 17.2 2.1 1.8 2 0 0 2 2 2 1 Basic region leucine zipper TSC22 PF01166.13 CDJ68393.1 - 0.003 17.5 0.2 0.007 16.3 0.1 1.6 1 1 0 1 1 1 1 TSC-22/dip/bun family FlaC_arch PF05377.6 CDJ68393.1 - 0.003 17.4 0.5 0.028 14.2 0.3 2.0 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Phasin PF05597.6 CDJ68393.1 - 0.0076 16.0 0.5 0.055 13.2 0.0 2.0 1 1 1 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Microtub_assoc PF07989.6 CDJ68393.1 - 0.01 15.6 0.6 0.016 15.0 0.4 1.3 1 0 0 1 1 1 1 Microtubule associated Herpes_BLRF2 PF05812.7 CDJ68393.1 - 0.012 15.3 0.9 0.018 14.8 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF904 PF06005.7 CDJ68393.1 - 0.013 15.8 3.0 0.022 15.0 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 CDJ68393.1 - 0.017 15.4 0.6 0.023 15.0 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) V-SNARE PF05008.10 CDJ68393.1 - 0.018 15.1 0.5 0.033 14.3 0.3 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF4140 PF13600.1 CDJ68393.1 - 0.023 15.1 0.7 0.031 14.7 0.5 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Shugoshin_N PF07558.6 CDJ68393.1 - 0.025 14.2 0.7 0.052 13.2 0.4 1.6 1 1 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TBPIP PF07106.8 CDJ68393.1 - 0.031 13.8 0.1 0.041 13.4 0.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Nnf1 PF03980.9 CDJ68393.1 - 0.038 13.9 0.6 0.04 13.9 0.4 1.3 1 1 0 1 1 1 0 Nnf1 Uds1 PF15456.1 CDJ68393.1 - 0.042 13.8 0.7 0.07 13.1 0.5 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 CDJ68393.1 - 0.042 13.8 1.4 0.059 13.3 0.9 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain KLRAQ PF10205.4 CDJ68393.1 - 0.045 13.7 0.3 0.069 13.1 0.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein APG6 PF04111.7 CDJ68393.1 - 0.049 12.6 0.1 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 MbeD_MobD PF04899.7 CDJ68393.1 - 0.049 13.5 0.8 0.11 12.4 0.4 1.6 2 0 0 2 2 1 0 MbeD/MobD like T2SF PF00482.18 CDJ68393.1 - 0.058 13.3 0.1 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Spc7 PF08317.6 CDJ68393.1 - 0.068 11.8 0.1 0.068 11.8 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIVA PF05103.8 CDJ68393.1 - 0.089 12.8 1.0 0.13 12.2 0.7 1.2 1 0 0 1 1 1 0 DivIVA protein Cep57_CLD_2 PF14197.1 CDJ68393.1 - 0.17 11.8 2.7 0.66 9.9 1.9 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 NPV_P10 PF05531.7 CDJ68393.1 - 0.29 11.3 1.3 1.4 9.2 0.9 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1843 PF08898.5 CDJ68393.1 - 1.2 9.2 4.7 2.4 8.2 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) AP2 PF00847.15 CDJ68395.1 - 1e-08 35.2 0.2 2.4e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 AP2 domain PRP3 PF08572.5 CDJ68395.1 - 0.011 15.0 5.5 2 7.7 0.0 2.4 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) AP2 PF00847.15 CDJ68396.1 - 5.9e-09 35.9 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 AP2 domain RNA_pol_Rpc4 PF05132.9 CDJ68397.1 - 1.3e-08 34.9 1.3 1.3e-08 34.9 0.9 3.3 2 2 0 2 2 2 1 RNA polymerase III RPC4 SSrecog PF03531.9 CDJ68398.1 - 6.5e-58 195.6 0.1 1.1e-57 194.9 0.1 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CDJ68398.1 - 6.8e-27 93.2 0.1 2e-26 91.7 0.1 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Nop14 PF04147.7 CDJ68398.1 - 0.65 7.8 13.8 0.91 7.3 9.6 1.2 1 0 0 1 1 1 0 Nop14-like family Vps35 PF03635.12 CDJ68400.1 - 5.4e-230 765.5 0.0 1.7e-152 509.3 0.0 2.6 2 1 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 RNA_pol_Rpb2_6 PF00562.23 CDJ68401.1 - 5.9e-112 374.2 0.0 8e-112 373.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CDJ68401.1 - 1.4e-42 144.9 0.0 2.1e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CDJ68401.1 - 1.3e-28 99.0 0.1 2.5e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 CDJ68401.1 - 1.5e-19 69.5 0.0 2.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 CDJ68401.1 - 4e-19 68.1 0.0 7.4e-19 67.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 CDJ68401.1 - 4.7e-16 58.7 0.0 9.9e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 CDJ68401.1 - 1.4e-09 37.7 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SR-25 PF10500.4 CDJ68401.1 - 0.79 9.1 37.9 0.05 13.0 4.4 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Dpy-30 PF05186.8 CDJ68402.1 - 4.4e-12 45.2 0.1 8e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.1 CDJ68402.1 - 2.1e-09 38.2 0.0 6.8e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 CDJ68402.1 - 1.6e-08 34.5 0.0 0.027 14.3 0.0 3.3 3 0 0 3 3 3 2 Adenylate kinase AAA_18 PF13238.1 CDJ68402.1 - 2.7e-05 24.4 1.4 8.6e-05 22.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 CDJ68402.1 - 0.0003 20.7 0.5 0.0003 20.7 0.3 3.5 4 0 0 4 4 2 1 AAA domain 6PF2K PF01591.13 CDJ68402.1 - 0.0011 18.0 0.0 2.1 7.3 0.0 2.9 3 0 0 3 3 3 2 6-phosphofructo-2-kinase BUD22 PF09073.5 CDJ68402.1 - 0.0021 17.1 6.4 0.0021 17.1 4.5 3.4 3 1 0 3 3 1 1 BUD22 Mg_chelatase PF01078.16 CDJ68402.1 - 0.0022 17.1 0.1 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.1 CDJ68402.1 - 0.0032 17.3 0.1 0.0032 17.3 0.0 1.8 2 0 0 2 2 1 1 Cytidylate kinase-like family AAA_33 PF13671.1 CDJ68402.1 - 0.0041 17.0 0.1 0.0041 17.0 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_23 PF13476.1 CDJ68402.1 - 0.0046 17.3 7.7 0.7 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CDJ68402.1 - 0.005 16.9 0.0 0.005 16.9 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CDJ68402.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CDJ68402.1 - 0.0069 15.8 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 CDJ68402.1 - 0.024 14.3 0.0 0.061 13.0 0.0 1.7 2 0 0 2 2 1 0 NTPase KTI12 PF08433.5 CDJ68402.1 - 0.031 13.4 0.0 0.031 13.4 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SKI PF01202.17 CDJ68402.1 - 0.047 13.5 3.3 0.33 10.7 0.0 3.0 3 0 0 3 3 3 0 Shikimate kinase AAA PF00004.24 CDJ68402.1 - 0.047 13.9 0.0 0.047 13.9 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CDJ68402.1 - 0.088 12.7 0.2 0.29 11.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain PRK PF00485.13 CDJ68402.1 - 0.16 11.5 0.1 0.33 10.4 0.1 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 CDJ68402.1 - 0.17 10.6 0.0 0.17 10.6 0.0 1.6 2 0 0 2 2 1 0 ArgK protein Neur_chan_memb PF02932.11 CDJ68402.1 - 0.37 10.6 4.9 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.4 CDJ68402.1 - 0.48 9.2 16.2 1.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Hid1 PF12722.2 CDJ68402.1 - 4.4 4.8 9.3 0.42 8.2 0.6 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein KAP_NTPase PF07693.9 CDJ68402.1 - 5.6 5.8 5.5 15 4.4 0.0 2.5 2 1 0 2 2 2 0 KAP family P-loop domain CBM-like PF14683.1 CDJ68403.1 - 0.0042 16.7 2.6 0.007 16.0 1.8 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III Cation_ATPase_C PF00689.16 CDJ68403.1 - 0.0058 16.1 7.6 0.0076 15.7 5.3 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus MpPF26 PF07666.6 CDJ68403.1 - 1.1 9.2 21.5 1.9 8.3 14.9 1.5 1 0 0 1 1 1 0 M penetrans paralogue family 26 DUF3753 PF12575.3 CDJ68403.1 - 1.7 8.5 16.5 4.3 7.2 4.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) RskA PF10099.4 CDJ68403.1 - 2.8 7.6 21.7 1.9 8.2 0.4 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4401 PF14351.1 CDJ68403.1 - 3.1 6.6 17.4 16 4.3 12.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF1129 PF06570.6 CDJ68403.1 - 4.9 6.4 9.9 9.6 5.4 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) RrnaAD PF00398.15 CDJ68404.1 - 1.1e-08 34.4 0.0 1.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TAF4 PF05236.9 CDJ68404.1 - 0.0002 20.7 6.0 0.00025 20.3 4.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Med15 PF09606.5 CDJ68404.1 - 0.0044 15.2 13.1 0.0053 15.0 9.0 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDJ68404.1 - 0.019 14.4 19.1 0.036 13.5 13.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAP1 PF08601.5 CDJ68404.1 - 0.025 14.2 3.6 0.029 14.0 2.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 BAF1_ABF1 PF04684.8 CDJ68404.1 - 0.052 12.4 9.4 0.065 12.0 6.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.8 CDJ68404.1 - 1.3 8.7 9.6 1.9 8.2 6.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CDJ68404.1 - 5 5.2 9.3 6.6 4.8 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Biotin_lipoyl PF00364.17 CDJ68405.1 - 7.9e-20 70.2 0.5 5.4e-18 64.4 0.1 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme 2-oxoacid_dh PF00198.18 CDJ68405.1 - 1.1e-09 37.9 0.0 2.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 CDJ68405.1 - 1.3e-08 34.3 0.0 1.3e-08 34.3 0.0 2.9 4 0 0 4 4 4 1 e3 binding domain HlyD_2 PF12700.2 CDJ68405.1 - 3.5e-05 23.1 2.8 1.1 8.3 0.0 4.1 3 1 1 4 4 4 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CDJ68405.1 - 0.00046 19.7 19.6 0.0032 17.1 0.0 5.0 4 0 0 4 4 4 2 Biotin-lipoyl like Spt20 PF12090.3 CDJ68405.1 - 0.03 13.6 2.9 0.055 12.8 2.0 1.4 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDJ68405.1 - 0.087 12.5 4.8 0.15 11.7 3.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.1 CDJ68405.1 - 0.54 9.1 6.4 0.94 8.4 4.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SR-25 PF10500.4 CDJ68405.1 - 5.1 6.4 23.7 0.53 9.7 3.6 2.8 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein Mago_nashi PF02792.9 CDJ68406.1 - 1.6e-24 86.1 4.1 1.8e-24 86.0 2.8 1.0 1 0 0 1 1 1 1 Mago nashi protein F5_F8_type_C PF00754.20 CDJ68407.1 - 1.5e-14 53.9 0.0 5.8e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 F5/8 type C domain DUF4632 PF15451.1 CDJ68408.1 - 0.014 15.2 0.1 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF935 PF06074.7 CDJ68408.1 - 0.1 11.2 2.7 0.098 11.3 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) SseC PF04888.7 CDJ68409.1 - 7.2 5.8 34.7 9.8 5.3 24.1 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CTNNBL PF08216.6 CDJ68410.1 - 6.3e-10 38.5 2.2 8.1e-10 38.2 1.6 1.1 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear FTCD_C PF04961.7 CDJ68410.1 - 0.0034 16.8 5.1 0.0042 16.5 3.5 1.2 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase SseC PF04888.7 CDJ68410.1 - 0.017 14.4 6.6 0.02 14.2 4.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Synuclein PF01387.12 CDJ68410.1 - 0.081 12.8 2.2 0.11 12.4 1.5 1.2 1 0 0 1 1 1 0 Synuclein PALP PF00291.20 CDJ68411.1 - 1.1e-11 44.5 0.0 3.6e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme SR-25 PF10500.4 CDJ68411.1 - 0.0095 15.4 7.1 0.013 14.9 4.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 CDJ68412.1 - 1.6e-21 76.6 0.0 1.3e-19 70.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68412.1 - 1.5e-12 47.1 0.0 2.3e-12 46.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CDJ68412.1 - 0.00032 19.8 0.0 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDJ68412.1 - 0.00045 20.0 1.5 0.0034 17.1 1.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CDJ68412.1 - 0.00098 18.1 0.0 0.011 14.6 0.0 2.1 2 1 0 2 2 2 1 Kinase-like LPP20 PF02169.11 CDJ68412.1 - 0.013 15.6 0.6 0.021 14.9 0.4 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein YrbL-PhoP_reg PF10707.4 CDJ68412.1 - 0.023 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ribosomal_60s PF00428.14 CDJ68412.1 - 0.046 14.1 3.5 0.099 13.0 2.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ68412.1 - 0.57 9.6 7.4 0.87 9.0 5.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SeqA PF03925.8 CDJ68413.1 - 0.19 11.4 4.1 0.69 9.5 0.2 2.4 2 0 0 2 2 2 0 SeqA protein Spt20 PF12090.3 CDJ68413.1 - 0.83 8.9 8.1 1.5 8.1 0.3 2.4 2 0 0 2 2 2 0 Spt20 family PHD_3 PF13922.1 CDJ68413.1 - 2.5 8.4 12.2 2.3 8.5 1.4 3.0 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx zf-CSL PF05207.8 CDJ68414.1 - 3.7e-15 55.1 0.0 5.5e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 CSL zinc finger DUF4228 PF14009.1 CDJ68414.1 - 6.1 6.9 15.2 0.71 9.9 2.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) SOG2 PF10428.4 CDJ68414.1 - 9.7 4.7 8.5 13 4.3 5.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Rad60-SLD PF11976.3 CDJ68415.1 - 1e-21 76.3 0.3 2e-21 75.4 0.0 1.6 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CDJ68415.1 - 1.3e-08 34.0 0.2 1.3e-08 34.0 0.1 1.5 1 1 1 2 2 2 1 Ubiquitin family Elf1 PF05129.8 CDJ68416.1 - 0.12 12.1 3.9 0.51 10.0 2.7 2.0 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like RAB3GAP2_N PF14655.1 CDJ68417.1 - 0.1 11.5 0.6 0.14 11.0 0.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3484 PF11983.3 CDJ68417.1 - 0.44 11.4 4.9 0.86 10.4 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) DUF1631 PF07793.6 CDJ68417.1 - 1.2 7.2 11.5 1.4 6.9 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Sterol-sensing PF12349.3 CDJ68418.1 - 1.8e-05 24.2 3.3 1.8e-05 24.2 2.3 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CDJ68418.1 - 0.00064 17.7 4.7 0.01 13.7 1.5 2.8 3 0 0 3 3 3 2 Patched family DUF4512 PF14975.1 CDJ68418.1 - 0.25 12.1 1.7 2.4 9.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4512) DUF3138 PF11336.3 CDJ68419.1 - 1.5 6.8 6.6 2.1 6.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Mitofilin PF09731.4 CDJ68422.1 - 0.00021 20.1 8.9 0.00024 19.9 6.2 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein SR-25 PF10500.4 CDJ68422.1 - 0.0012 18.3 11.0 0.0015 18.0 7.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Prefoldin_2 PF01920.15 CDJ68422.1 - 0.0014 18.3 3.9 0.0014 18.3 2.7 1.9 2 0 0 2 2 2 1 Prefoldin subunit Radial_spoke PF04712.7 CDJ68422.1 - 0.0019 17.0 12.3 0.048 12.3 1.9 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein Striatin PF08232.7 CDJ68422.1 - 0.003 17.8 15.2 0.0043 17.3 10.6 1.2 1 0 0 1 1 1 1 Striatin family Dpy-30 PF05186.8 CDJ68422.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Dpy-30 motif Nup88 PF10168.4 CDJ68422.1 - 0.02 12.7 4.4 0.024 12.5 3.1 1.1 1 0 0 1 1 1 0 Nuclear pore component PRTP PF01366.13 CDJ68422.1 - 0.024 12.6 5.0 0.028 12.4 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DDHD PF02862.12 CDJ68422.1 - 0.032 14.0 9.4 0.047 13.4 6.5 1.2 1 0 0 1 1 1 0 DDHD domain Cwf_Cwc_15 PF04889.7 CDJ68422.1 - 0.064 12.9 14.1 0.093 12.4 9.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3573 PF12097.3 CDJ68422.1 - 0.068 11.7 3.1 0.077 11.6 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DNA_pol_viral_N PF00242.12 CDJ68422.1 - 0.072 12.1 7.0 0.083 11.9 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Atg14 PF10186.4 CDJ68422.1 - 0.11 11.4 8.3 0.13 11.2 5.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bul1_C PF04426.7 CDJ68422.1 - 0.11 11.6 5.8 0.14 11.3 4.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus Ycf1 PF05758.7 CDJ68422.1 - 0.26 8.9 7.2 0.3 8.7 5.0 1.0 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 CDJ68422.1 - 0.3 11.1 14.4 0.43 10.5 10.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HAUS6_N PF14661.1 CDJ68422.1 - 0.3 10.3 10.7 0.37 10.0 7.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SPX PF03105.14 CDJ68422.1 - 0.4 10.4 12.0 0.47 10.1 8.3 1.1 1 0 0 1 1 1 0 SPX domain CobT PF06213.7 CDJ68422.1 - 0.4 9.7 12.0 0.55 9.3 8.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 CDJ68422.1 - 0.44 9.7 5.3 0.53 9.5 3.7 1.1 1 0 0 1 1 1 0 NOA36 protein V_ATPase_I PF01496.14 CDJ68422.1 - 0.52 8.0 7.4 0.63 7.8 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myc_N PF01056.13 CDJ68422.1 - 0.56 9.3 16.3 0.27 10.3 9.8 1.4 1 1 0 1 1 1 0 Myc amino-terminal region BTV_NS2 PF04514.7 CDJ68422.1 - 0.56 9.0 9.5 0.72 8.6 6.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 CDJ68422.1 - 0.62 8.0 13.2 0.74 7.7 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein APC_CDC26 PF10471.4 CDJ68422.1 - 0.63 10.8 17.7 1.9 9.3 12.3 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Lin-8 PF03353.10 CDJ68422.1 - 0.63 9.2 11.8 0.84 8.8 8.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RP-C_C PF11800.3 CDJ68422.1 - 0.72 9.5 8.9 1.2 8.8 6.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.2 CDJ68422.1 - 0.78 7.3 11.8 0.89 7.1 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0697 PF15117.1 CDJ68422.1 - 0.8 9.5 4.1 1.9 8.2 2.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 SAPS PF04499.10 CDJ68422.1 - 0.94 8.0 10.8 3 6.3 7.2 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DivIVA PF05103.8 CDJ68422.1 - 0.99 9.4 15.7 1.5 8.8 10.9 1.2 1 0 0 1 1 1 0 DivIVA protein CENP-B_dimeris PF09026.5 CDJ68422.1 - 1 9.6 6.6 1.8 8.8 4.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM60A PF15396.1 CDJ68422.1 - 1.2 8.8 10.0 1.6 8.4 6.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4407 PF14362.1 CDJ68422.1 - 1.4 7.7 6.0 1.6 7.6 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 CDJ68422.1 - 1.6 8.5 11.8 2.1 8.1 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.6 CDJ68422.1 - 1.7 6.9 8.6 1.8 6.8 5.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Neur_chan_memb PF02932.11 CDJ68422.1 - 1.7 8.4 3.8 1.9 8.2 2.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0560 PF10577.4 CDJ68422.1 - 1.8 6.7 11.8 2.3 6.3 8.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.12 CDJ68422.1 - 2 7.1 7.6 2.3 6.9 5.2 1.1 1 0 0 1 1 1 0 Presenilin Apc1 PF12859.2 CDJ68422.1 - 2 8.6 5.8 3.1 8.0 4.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 YlbD_coat PF14071.1 CDJ68422.1 - 2.3 8.3 12.9 1.4 8.9 4.0 2.2 2 0 0 2 2 2 0 Putative coat protein Spt20 PF12090.3 CDJ68423.1 - 0.14 11.5 8.7 0.28 10.5 0.9 2.7 3 0 0 3 3 3 0 Spt20 family DUF3801 PF12687.2 CDJ68423.1 - 1.4 8.4 10.1 0.36 10.3 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Baculo_PP31 PF05311.6 CDJ68423.1 - 7.2 5.7 13.0 0.23 10.7 4.0 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) BAF1_ABF1 PF04684.8 CDJ68424.1 - 0.0044 15.9 10.7 0.0044 15.9 7.4 8.8 3 2 5 9 9 9 1 BAF1 / ABF1 chromatin reorganising factor CAF-1_p150 PF11600.3 CDJ68425.1 - 0.063 12.6 21.7 0.15 11.3 7.9 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDJ68425.1 - 0.096 12.1 39.3 0.03 13.8 5.2 2.4 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2638 PF10937.3 CDJ68425.1 - 5 8.1 9.2 24 5.9 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) PAT1 PF09770.4 CDJ68425.1 - 9.2 4.3 26.5 15 3.6 18.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP-synt_ab PF00006.20 CDJ68426.1 - 6.3e-58 195.8 0.0 8.4e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CDJ68426.1 - 2.7e-16 60.0 0.5 5.5e-16 59.0 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CDJ68426.1 - 1.3e-05 25.3 0.5 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, beta-barrel domain DUF4131 PF13567.1 CDJ68426.1 - 0.88 8.9 9.4 14 5.0 6.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Alkyl_sulf_dimr PF14863.1 CDJ68427.1 - 0.065 13.4 2.7 0.15 12.3 1.8 1.5 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation SR-25 PF10500.4 CDJ68427.1 - 6.6 6.1 17.8 15 5.0 12.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.3 CDJ68428.1 - 0.067 12.5 5.2 1.6 8.0 0.6 2.2 2 0 0 2 2 2 0 Spt20 family RAB3GAP2_N PF14655.1 CDJ68428.1 - 0.084 11.8 17.4 0.18 10.8 5.2 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDJ68428.1 - 0.35 10.5 6.8 2.4 7.8 0.8 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SR-25 PF10500.4 CDJ68428.1 - 3.7 6.9 16.8 0.032 13.6 1.9 2.8 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1395 PF07160.7 CDJ68428.1 - 4.8 6.6 7.3 0.48 9.8 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) SR-25 PF10500.4 CDJ68429.1 - 0.7 9.3 34.3 0.6 9.5 7.9 2.4 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Rifin_STEVOR PF02009.11 CDJ68429.1 - 0.92 9.0 0.0 0.92 9.0 0.0 2.9 2 1 1 3 3 3 0 Rifin/stevor family DUF1980 PF09323.5 CDJ68429.1 - 3.6 7.2 6.7 0.64 9.7 2.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Herpes_UL87 PF03043.9 CDJ68429.1 - 7.1 4.8 9.3 11 4.2 6.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family rve PF00665.21 CDJ68430.1 - 3.7e-20 72.2 0.0 1.5e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDJ68430.1 - 3.1e-13 49.1 0.0 5.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDJ68430.1 - 0.0003 20.1 1.2 0.00058 19.2 0.8 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger rve_3 PF13683.1 CDJ68430.1 - 0.058 12.9 0.2 0.4 10.2 0.1 2.4 2 0 0 2 2 2 0 Integrase core domain rve PF00665.21 CDJ68431.1 - 1.1e-17 64.2 0.1 7.4e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CDJ68431.1 - 0.0099 15.3 0.2 0.027 13.9 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain YsaB PF13983.1 CDJ68431.1 - 0.018 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 YsaB-like lipoprotein FHIPEP PF00771.15 CDJ68436.1 - 4.6e-05 21.9 2.5 5.6e-05 21.6 1.8 1.0 1 0 0 1 1 1 1 FHIPEP family LRR_8 PF13855.1 CDJ68436.1 - 0.00013 21.5 0.7 0.00046 19.8 0.2 2.0 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 CDJ68436.1 - 0.00018 21.0 1.3 0.0019 17.7 0.3 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) SprA-related PF12118.3 CDJ68436.1 - 0.0019 17.5 20.0 0.0024 17.2 13.8 1.1 1 0 0 1 1 1 1 SprA-related family TFIIA PF03153.8 CDJ68436.1 - 0.0034 17.3 15.9 0.0039 17.1 11.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit LRR_9 PF14580.1 CDJ68436.1 - 0.0041 16.7 0.1 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat FimP PF09766.4 CDJ68436.1 - 0.018 14.1 8.3 0.025 13.6 5.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF3371 PF11851.3 CDJ68436.1 - 0.024 15.3 4.2 0.024 15.3 2.9 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF3371) Suf PF05843.9 CDJ68436.1 - 0.026 14.2 5.7 0.032 13.9 3.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SAGA-Tad1 PF12767.2 CDJ68436.1 - 0.044 13.4 6.8 0.064 12.9 4.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF912 PF06024.7 CDJ68436.1 - 0.057 13.4 2.4 0.12 12.4 1.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SR-25 PF10500.4 CDJ68436.1 - 0.057 12.8 15.7 0.056 12.9 4.6 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PH_4 PF15404.1 CDJ68436.1 - 0.1 12.1 1.4 0.18 11.3 1.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Spt20 PF12090.3 CDJ68436.1 - 0.11 11.7 3.2 0.16 11.2 2.2 1.4 1 0 0 1 1 1 0 Spt20 family Apt1 PF10351.4 CDJ68436.1 - 0.35 9.6 4.3 0.51 9.1 3.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Serinc PF03348.10 CDJ68436.1 - 0.57 8.8 1.5 0.69 8.5 1.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) LRR_1 PF00560.28 CDJ68436.1 - 1 9.6 3.5 6.9 7.1 0.1 3.3 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 CDJ68436.1 - 1.1 9.5 3.7 4.5 7.6 0.5 2.8 2 1 1 3 3 2 0 Leucine Rich repeat DUF3043 PF11241.3 CDJ68436.1 - 4.2 6.9 5.5 6.9 6.2 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) MIP-T3 PF10243.4 CDJ68437.1 - 2 6.7 54.9 2.4 6.5 38.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4407 PF14362.1 CDJ68437.1 - 3 6.6 57.2 1 8.2 37.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Utp14 PF04615.8 CDJ68437.1 - 6.9 4.6 49.3 8 4.4 34.2 1.0 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.1 CDJ68437.1 - 7.9 6.7 33.0 10 6.4 22.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Pkinase PF00069.20 CDJ68438.1 - 1.1e-23 83.7 0.3 6.6e-09 35.2 0.0 4.6 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68438.1 - 0.0001 21.4 0.0 0.016 14.2 0.0 3.3 3 1 0 3 3 3 1 Protein tyrosine kinase BAF1_ABF1 PF04684.8 CDJ68438.1 - 0.0042 16.0 3.0 0.0042 16.0 2.1 7.9 7 1 1 8 8 8 2 BAF1 / ABF1 chromatin reorganising factor Med3 PF11593.3 CDJ68439.1 - 6.3 5.9 14.3 1.4 8.0 3.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Sporozoite_P67 PF05642.6 CDJ68440.1 - 0.0026 15.7 0.4 0.003 15.5 0.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen LMBR1 PF04791.11 CDJ68440.1 - 0.39 9.2 4.0 0.49 8.9 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Vma12 PF11712.3 CDJ68440.1 - 1.4 8.6 4.2 2.4 7.8 2.9 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Mnd1 PF03962.10 CDJ68440.1 - 2.4 7.7 7.1 3.4 7.2 4.9 1.3 1 0 0 1 1 1 0 Mnd1 family AAA_13 PF13166.1 CDJ68440.1 - 2.8 6.3 9.2 3.5 5.9 6.4 1.1 1 0 0 1 1 1 0 AAA domain DUF4557 PF15101.1 CDJ68440.1 - 2.8 7.7 11.0 4.4 7.0 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1682 PF07946.9 CDJ68440.1 - 7.6 5.2 10.4 10 4.8 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Med15 PF09606.5 CDJ68441.1 - 2 6.5 84.5 2.4 6.2 58.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FUSC PF04632.7 CDJ68442.1 - 0.86 7.9 5.6 1 7.6 3.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family ThiS PF02597.15 CDJ68442.1 - 3.2 8.2 5.8 9.7 6.7 0.3 2.7 1 1 2 3 3 3 0 ThiS family Swi5 PF07061.6 CDJ68442.1 - 6.6 6.6 7.7 31 4.4 5.4 2.1 1 1 0 1 1 1 0 Swi5 Ribosomal_60s PF00428.14 CDJ68443.1 - 0.59 10.5 13.7 0.064 13.6 4.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein CytochromB561_N PF09786.4 CDJ68443.1 - 0.87 7.9 5.2 0.83 8.0 3.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pex14_N PF04695.8 CDJ68443.1 - 6.5 6.8 11.7 6.9 6.7 7.9 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.3 CDJ68443.1 - 8.1 5.9 12.4 13 5.3 8.6 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Med15 PF09606.5 CDJ68444.1 - 0.00012 20.4 13.2 0.00012 20.4 9.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4483 PF14825.1 CDJ68444.1 - 0.0011 18.7 2.4 0.0013 18.4 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) FimP PF09766.4 CDJ68444.1 - 0.0031 16.6 6.0 0.0037 16.4 4.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein Presenilin PF01080.12 CDJ68444.1 - 0.0077 15.1 3.5 0.0097 14.7 2.4 1.0 1 0 0 1 1 1 1 Presenilin DNA_pol_viral_N PF00242.12 CDJ68444.1 - 0.0084 15.1 7.7 0.0082 15.2 5.3 1.1 1 0 0 1 1 1 1 DNA polymerase (viral) N-terminal domain DUF572 PF04502.8 CDJ68444.1 - 0.012 14.8 5.5 0.015 14.5 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MACPF PF01823.14 CDJ68444.1 - 0.031 13.9 1.7 0.043 13.4 1.2 1.2 1 0 0 1 1 1 0 MAC/Perforin domain Spt20 PF12090.3 CDJ68444.1 - 0.032 13.5 1.6 0.041 13.2 1.1 1.4 1 0 0 1 1 1 0 Spt20 family DUF3987 PF13148.1 CDJ68444.1 - 0.057 11.9 3.9 0.07 11.6 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Herpes_TAF50 PF03326.8 CDJ68444.1 - 0.14 11.1 17.9 0.16 10.8 12.4 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) AAA_23 PF13476.1 CDJ68444.1 - 0.19 12.0 2.7 0.24 11.7 1.9 1.2 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDJ68444.1 - 0.2 9.8 15.3 0.22 9.7 10.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDJ68444.1 - 0.36 9.0 10.6 0.5 8.5 7.3 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF788 PF05620.6 CDJ68444.1 - 0.42 10.4 5.6 0.65 9.8 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Cwf_Cwc_15 PF04889.7 CDJ68444.1 - 0.63 9.7 9.3 0.83 9.3 6.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4175 PF13779.1 CDJ68444.1 - 0.69 7.5 18.6 0.78 7.3 12.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pol_alpha_B_N PF08418.5 CDJ68444.1 - 1.4 8.3 12.2 1.9 7.9 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Hid1 PF12722.2 CDJ68444.1 - 1.6 6.3 7.7 1.8 6.1 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1183 PF06682.7 CDJ68444.1 - 1.7 8.1 13.1 2.2 7.7 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) vMSA PF00695.14 CDJ68444.1 - 2.1 7.4 4.6 1.9 7.6 2.4 1.4 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus DUF4557 PF15101.1 CDJ68444.1 - 2.4 7.9 14.7 3.2 7.5 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1675 PF07897.6 CDJ68444.1 - 2.5 7.9 11.0 3.2 7.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Pex16 PF08610.5 CDJ68444.1 - 2.7 6.9 6.2 3.4 6.5 4.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4407 PF14362.1 CDJ68444.1 - 3.8 6.3 9.7 4.6 6.0 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2217 PF10265.4 CDJ68444.1 - 4.7 5.8 10.4 5.8 5.5 7.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DivIC PF04977.10 CDJ68444.1 - 5.3 6.6 11.2 7.7 6.0 7.8 1.2 1 0 0 1 1 1 0 Septum formation initiator Neur_chan_memb PF02932.11 CDJ68444.1 - 8.2 6.2 7.0 11 5.7 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_E_B PF04042.11 CDJ68445.1 - 4.7e-29 101.1 0.0 1.1e-28 99.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SR-25 PF10500.4 CDJ68445.1 - 6.8e-05 22.4 16.0 0.00011 21.7 11.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Smg4_UPF3 PF03467.10 CDJ68445.1 - 0.0047 16.9 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 Smg-4/UPF3 family RR_TM4-6 PF06459.7 CDJ68445.1 - 0.26 11.1 8.0 0.57 10.0 5.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IFT46_B_C PF12317.3 CDJ68445.1 - 0.26 10.6 1.6 0.41 9.9 1.1 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Corona_nucleoca PF00937.13 CDJ68445.1 - 0.93 8.3 15.4 1.7 7.5 10.7 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CBP4 PF07960.6 CDJ68445.1 - 2.4 7.7 14.5 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 CBP4 Spt20 PF12090.3 CDJ68445.1 - 3.3 7.0 7.5 5.5 6.2 5.2 1.3 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.4 CDJ68445.1 - 4 5.5 25.7 7.5 4.6 17.8 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDJ68445.1 - 4.5 6.9 14.5 7.4 6.2 10.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) IncA PF04156.9 CDJ68446.1 - 0.003 17.1 25.0 0.0044 16.6 17.4 1.2 1 0 0 1 1 1 1 IncA protein DUF445 PF04286.7 CDJ68446.1 - 0.018 14.5 5.8 0.021 14.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) VIT1 PF01988.14 CDJ68446.1 - 0.019 14.4 7.2 0.024 14.1 5.0 1.1 1 0 0 1 1 1 0 VIT family GerPC PF10737.4 CDJ68446.1 - 0.023 14.4 9.1 0.03 14.0 6.3 1.1 1 0 0 1 1 1 0 Spore germination protein GerPC Med15 PF09606.5 CDJ68446.1 - 0.045 11.9 36.6 0.063 11.4 25.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HAD_2 PF13419.1 CDJ68446.1 - 0.063 13.5 2.1 0.078 13.1 1.4 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HI0933_like PF03486.9 CDJ68446.1 - 0.064 11.7 8.5 0.08 11.3 5.9 1.2 1 0 0 1 1 1 0 HI0933-like protein TraT PF05818.7 CDJ68446.1 - 0.066 12.6 4.5 0.083 12.2 3.1 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF3533 PF12051.3 CDJ68446.1 - 0.39 9.4 11.3 0.52 9.0 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Activator_LAG-3 PF11498.3 CDJ68446.1 - 0.47 9.1 37.5 0.57 8.8 26.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PBP_sp32 PF07222.7 CDJ68446.1 - 0.57 9.3 6.7 0.71 9.0 4.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1832 PF08870.6 CDJ68446.1 - 0.58 9.8 5.2 1.3 8.7 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1832) Bac_GDH PF05088.7 CDJ68446.1 - 0.62 7.3 10.4 0.71 7.1 7.2 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase RPA_C PF08784.6 CDJ68446.1 - 0.62 10.5 7.1 0.96 9.9 4.9 1.3 1 0 0 1 1 1 0 Replication protein A C terminal Peptidase_S15 PF02129.13 CDJ68446.1 - 0.63 9.4 8.6 0.74 9.1 5.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) HemX PF04375.9 CDJ68446.1 - 0.67 8.4 30.8 0.83 8.1 21.3 1.1 1 0 0 1 1 1 0 HemX DNA_pack_N PF02500.10 CDJ68446.1 - 0.67 9.4 5.7 0.77 9.2 4.0 1.1 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus DUF2232 PF09991.4 CDJ68446.1 - 0.9 8.4 10.0 0.75 8.7 6.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Penicillinase_R PF03965.11 CDJ68446.1 - 1 9.5 8.5 1.1 9.3 5.1 1.6 1 1 0 1 1 1 0 Penicillinase repressor DUF1690 PF07956.6 CDJ68446.1 - 1.3 8.9 13.5 1.8 8.5 9.3 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2497 PF10691.4 CDJ68446.1 - 1.6 8.7 6.9 2.1 8.3 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2497) DUF773 PF05600.7 CDJ68446.1 - 1.7 7.3 13.7 2.1 7.0 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF773) Zea_mays_MuDR PF05928.6 CDJ68446.1 - 2.2 7.6 4.8 2.5 7.4 3.3 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) DUF3450 PF11932.3 CDJ68446.1 - 2.2 7.4 28.9 2.6 7.2 20.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1539 PF07560.6 CDJ68446.1 - 2.2 8.1 6.7 3 7.7 4.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF342 PF03961.8 CDJ68446.1 - 2.3 6.5 5.0 2.5 6.4 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PYRIN PF02758.11 CDJ68446.1 - 2.3 7.9 12.0 3.3 7.4 8.3 1.3 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain DUF2127 PF09900.4 CDJ68446.1 - 2.5 8.1 8.9 2.6 8.0 5.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2127) DUF2924 PF11149.3 CDJ68446.1 - 2.6 8.0 10.6 3.3 7.7 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) PAT1 PF09770.4 CDJ68446.1 - 4.3 5.4 30.4 4.6 5.3 21.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1631 PF07793.6 CDJ68446.1 - 5 5.1 29.0 5.8 4.9 20.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Cas_APE2256 PF09651.5 CDJ68446.1 - 5.4 6.7 7.0 15 5.3 4.8 1.9 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) TFIIA PF03153.8 CDJ68446.1 - 5.7 6.7 23.6 7.2 6.4 16.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4403 PF14356.1 CDJ68446.1 - 8.6 4.5 12.4 0.95 7.6 5.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4403) PseudoU_synth_2 PF00849.17 CDJ68447.1 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase Spt20 PF12090.3 CDJ68447.1 - 0.036 13.3 2.8 0.97 8.7 0.1 2.2 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.4 CDJ68448.1 - 0.005 16.3 12.1 0.0052 16.2 8.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ68448.1 - 2.9 7.2 5.3 3.3 7.0 3.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF755 PF05501.6 CDJ68448.1 - 3.1 7.8 15.9 3.9 7.5 11.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Syntaphilin PF15290.1 CDJ68448.1 - 3.6 6.9 8.5 4.4 6.6 5.9 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp PAT1 PF09770.4 CDJ68451.1 - 0.12 10.5 45.5 0.15 10.2 31.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDJ68451.1 - 0.16 11.7 26.8 0.74 9.5 2.0 2.1 2 0 0 2 2 2 0 DDHD domain DUF605 PF04652.11 CDJ68451.1 - 0.23 10.8 29.1 0.32 10.3 20.2 1.2 1 0 0 1 1 1 0 Vta1 like DUF1510 PF07423.6 CDJ68451.1 - 6.9 5.9 21.4 0.46 9.8 9.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2058 PF09831.4 CDJ68451.1 - 7.4 6.4 38.2 2 8.2 24.3 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Ribosomal_60s PF00428.14 CDJ68451.1 - 9.9 6.6 12.3 16 5.9 8.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4557 PF15101.1 CDJ68452.1 - 0.019 14.8 1.0 0.027 14.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Sipho_Gp37 PF14594.1 CDJ68452.1 - 0.038 13.2 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein RNA_pol_Rpb1_5 PF04998.12 CDJ68453.1 - 3.6e-46 157.6 0.0 4.9e-45 153.9 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 CDK2AP PF09806.4 CDJ68453.1 - 1.2 9.3 8.6 1 9.5 1.7 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein UPF0565 PF10561.4 CDJ68454.1 - 0.012 14.5 7.9 0.017 14.0 5.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0565 Peptidase_S46 PF10459.4 CDJ68454.1 - 0.032 12.6 12.2 0.036 12.4 8.4 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF2360 PF10152.4 CDJ68454.1 - 0.038 14.2 7.0 0.048 13.9 4.8 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Dehydrin PF00257.14 CDJ68454.1 - 0.067 13.5 5.3 0.14 12.4 3.7 1.6 1 0 0 1 1 1 0 Dehydrin GAGA_bind PF06217.7 CDJ68454.1 - 0.072 13.0 9.1 0.082 12.8 6.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FUSC PF04632.7 CDJ68454.1 - 0.17 10.2 19.3 0.21 9.9 13.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4366 PF14283.1 CDJ68454.1 - 0.19 11.1 4.8 0.26 10.7 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RNase_H2-Ydr279 PF09468.5 CDJ68454.1 - 0.24 10.5 3.7 0.27 10.3 2.5 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Activator_LAG-3 PF11498.3 CDJ68454.1 - 0.26 9.9 33.2 0.31 9.7 23.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF572 PF04502.8 CDJ68454.1 - 0.3 10.2 10.2 0.4 9.8 7.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.8 CDJ68454.1 - 0.39 10.5 23.8 0.48 10.2 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF853 PF05872.7 CDJ68454.1 - 0.4 8.9 10.2 0.49 8.6 7.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF1764 PF08576.5 CDJ68454.1 - 0.47 11.2 8.5 0.82 10.4 5.9 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Med15 PF09606.5 CDJ68454.1 - 0.79 7.8 34.1 0.84 7.7 23.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MPLKIP PF15502.1 CDJ68454.1 - 0.99 10.0 16.8 1.5 9.4 11.7 1.3 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein PNGaseA PF12222.3 CDJ68454.1 - 1.4 7.6 13.4 1.8 7.3 9.3 1.2 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A FLO_LFY PF01698.11 CDJ68454.1 - 1.8 7.3 11.0 2.2 7.0 7.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4407 PF14362.1 CDJ68454.1 - 2.3 7.0 19.0 3 6.7 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AUX_IAA PF02309.11 CDJ68454.1 - 3.1 7.4 6.8 3.6 7.2 4.7 1.2 1 0 0 1 1 1 0 AUX/IAA family PAT1 PF09770.4 CDJ68454.1 - 3.4 5.7 26.7 4 5.5 18.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 CDJ68454.1 - 3.7 6.9 10.9 5.3 6.4 7.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hid1 PF12722.2 CDJ68454.1 - 3.8 5.0 10.3 4.4 4.8 7.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MRP-S31 PF15433.1 CDJ68454.1 - 4.2 6.7 11.5 4.7 6.5 8.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Peptidase_S15 PF02129.13 CDJ68454.1 - 5.6 6.3 10.5 7.3 5.9 7.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Gag_spuma PF03276.9 CDJ68454.1 - 5.7 5.1 17.8 6.6 4.9 12.4 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF4139 PF13598.1 CDJ68454.1 - 9.1 5.4 13.1 12 5.0 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) SAP PF02037.22 CDJ68455.1 - 5.2e-15 54.5 0.2 1.5e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 CDJ68455.1 - 0.0015 18.0 0.1 0.0038 16.7 0.0 1.7 1 1 0 1 1 1 1 HeH/LEM domain Hamartin PF04388.7 CDJ68455.1 - 0.12 11.0 5.9 0.14 10.8 4.1 1.0 1 0 0 1 1 1 0 Hamartin protein CAF-1_p150 PF11600.3 CDJ68455.1 - 0.24 10.7 7.7 0.46 9.8 5.4 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Adaptin_N PF01602.15 CDJ68456.1 - 2e-56 191.3 0.2 1.5e-31 109.3 0.2 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 CDJ68456.1 - 0.2 11.4 0.5 0.79 9.5 0.3 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CDJ68456.1 - 6.5 7.1 20.5 4.1 7.7 0.1 6.3 6 0 0 6 6 6 0 HEAT repeat XPG_I PF00867.13 CDJ68457.1 - 5e-29 100.2 0.0 1.1e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CDJ68457.1 - 2.1e-26 92.0 0.3 9e-26 90.0 0.0 2.2 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CDJ68457.1 - 0.00022 21.3 0.0 0.00073 19.7 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF4414 PF14377.1 CDJ68457.1 - 6.3 6.7 12.5 0.41 10.5 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Activator_LAG-3 PF11498.3 CDJ68458.1 - 0.0038 16.0 48.5 0.0038 16.0 33.6 5.2 5 0 0 5 5 5 1 Transcriptional activator LAG-3 RAP1 PF07218.6 CDJ68458.1 - 0.12 10.4 5.9 0.28 9.2 4.1 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Corona_nucleoca PF00937.13 CDJ68460.1 - 6.6 5.5 9.8 18 4.1 5.0 2.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein MCM PF00493.18 CDJ68462.1 - 2.5e-58 197.4 11.1 4.8e-58 196.5 0.3 2.4 1 1 1 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 CDJ68462.1 - 0.00017 20.7 0.1 0.0016 17.6 0.1 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CDJ68462.1 - 0.0034 16.8 0.2 0.027 13.9 0.2 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CDJ68462.1 - 0.039 13.6 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CDJ68462.1 - 0.14 12.3 1.2 1 9.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain Med15 PF09606.5 CDJ68462.1 - 0.17 10.0 39.6 0.064 11.4 25.8 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_M20 PF01546.23 CDJ68462.1 - 4.5 6.7 6.3 18 4.7 4.4 2.1 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 RPA_C PF08784.6 CDJ68463.1 - 0.013 15.9 0.2 0.073 13.4 0.0 2.2 3 0 0 3 3 3 0 Replication protein A C terminal SelB-wing_2 PF09106.6 CDJ68463.1 - 0.31 11.0 3.5 0.16 11.9 0.3 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix LexA_DNA_bind PF01726.11 CDJ68463.1 - 0.6 9.7 3.3 0.65 9.6 0.1 2.7 3 0 0 3 3 3 0 LexA DNA binding domain SR-25 PF10500.4 CDJ68463.1 - 1.4 8.3 8.1 2.7 7.4 5.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDJ68464.1 - 0.0086 15.8 8.9 0.06 13.0 4.4 2.1 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) FMN_dh PF01070.13 CDJ68464.1 - 0.41 9.4 4.6 0.66 8.7 3.2 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase RRM_1 PF00076.17 CDJ68465.1 - 2.9e-05 23.5 0.0 5.9e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ68465.1 - 0.0025 17.7 0.0 0.0064 16.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 CDJ68466.1 - 0.04 14.2 0.1 0.083 13.2 0.1 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF1744 PF08490.7 CDJ68467.1 - 5.4e-12 44.9 0.0 5.4e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1744) Ribosomal_60s PF00428.14 CDJ68468.1 - 0.011 16.1 12.2 0.011 16.1 8.5 2.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein PT-HINT PF07591.6 CDJ68468.1 - 0.014 15.2 0.6 0.022 14.6 0.4 1.3 1 0 0 1 1 1 0 Pretoxin HINT domain Med15 PF09606.5 CDJ68468.1 - 1.9 6.6 23.3 2.2 6.3 16.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Chorion_2 PF03964.10 CDJ68468.1 - 2.3 8.8 10.0 0.12 12.9 3.0 1.9 2 0 0 2 2 2 0 Chorion family 2 DUF4349 PF14257.1 CDJ68468.1 - 8.5 5.5 13.4 0.21 10.8 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) BAF1_ABF1 PF04684.8 CDJ68469.1 - 0.0012 17.8 8.0 0.0012 17.8 5.5 8.1 5 3 2 8 8 8 1 BAF1 / ABF1 chromatin reorganising factor Arv1 PF04161.8 CDJ68470.1 - 8.5e-28 97.6 0.9 1.8e-25 90.0 0.4 2.4 2 0 0 2 2 2 2 Arv1-like family CDC45 PF02724.9 CDJ68470.1 - 0.029 12.4 9.4 0.031 12.3 1.5 2.9 3 0 0 3 3 3 0 CDC45-like protein DUF4386 PF14329.1 CDJ68470.1 - 0.2 11.1 40.1 0.075 12.5 13.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Nucleoplasmin PF03066.10 CDJ68470.1 - 0.23 10.9 8.2 0.51 9.8 5.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin Herpes_DNAp_acc PF04929.7 CDJ68470.1 - 0.32 9.9 19.6 0.067 12.1 3.4 2.3 1 1 1 2 2 2 0 Herpes DNA replication accessory factor DUF2052 PF09747.4 CDJ68470.1 - 2.2 8.1 21.7 0.14 12.0 2.6 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) PCI_Csn8 PF10075.4 CDJ68472.1 - 4.4e-16 58.9 0.0 7.3e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CDJ68472.1 - 3.1e-10 39.9 0.0 4.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Ribosomal_60s PF00428.14 CDJ68472.1 - 0.0063 16.8 0.9 0.015 15.6 0.6 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein PCI PF01399.22 CDJ68472.1 - 0.14 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 PCI domain Sdh5 PF03937.11 CDJ68473.1 - 0.051 13.2 0.2 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase ACDC PF14733.1 CDJ68476.1 - 4.3e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 1 1 2 2 2 1 AP2-coincident C-terminal SRC-1 PF08832.5 CDJ68476.1 - 1.3 9.8 0.1 1.3 9.8 0.0 2.9 3 0 0 3 3 3 0 Steroid receptor coactivator RED_N PF07808.8 CDJ68477.1 - 1.6e-22 79.9 11.1 1.6e-22 79.9 7.7 2.1 1 1 1 2 2 2 1 RED-like protein N-terminal region Ribosomal_60s PF00428.14 CDJ68477.1 - 0.026 14.9 2.3 0.052 13.9 0.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Med25_NR-box PF11244.3 CDJ68477.1 - 0.22 12.0 10.7 2.8 8.4 0.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing Herpes_UL3 PF03369.8 CDJ68477.1 - 0.3 11.0 0.0 0.3 11.0 0.0 1.9 2 1 0 2 2 2 0 Herpesvirus UL3 protein MMR1 PF08505.5 CDJ68477.1 - 0.72 9.8 7.2 1.1 9.2 5.0 1.3 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DRY_EERY PF09750.4 CDJ68477.1 - 9.7 6.3 11.4 2.4 8.2 5.0 1.9 1 1 1 2 2 2 0 Alternative splicing regulator CDK2AP PF09806.4 CDJ68478.1 - 0.032 14.4 16.0 0.043 14.0 11.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2217 PF10265.4 CDJ68478.1 - 0.033 12.9 8.5 0.038 12.7 5.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) AF-4 PF05110.8 CDJ68478.1 - 0.063 11.1 31.2 0.073 10.9 21.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Parvo_coat_N PF08398.5 CDJ68478.1 - 0.067 12.9 0.7 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Sporozoite_P67 PF05642.6 CDJ68478.1 - 0.14 9.9 11.2 0.15 9.9 7.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 CDJ68478.1 - 0.21 9.6 12.3 0.22 9.5 8.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Plasmodium_Vir PF05795.6 CDJ68478.1 - 0.34 10.0 4.4 0.4 9.8 3.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.1 CDJ68478.1 - 0.36 10.5 6.3 0.46 10.1 4.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAP1 PF08601.5 CDJ68478.1 - 0.37 10.4 18.7 0.42 10.2 13.0 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 NPR3 PF03666.8 CDJ68478.1 - 0.41 9.1 9.5 0.52 8.7 6.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.10 CDJ68478.1 - 0.55 8.8 3.5 0.57 8.7 2.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0561 PF10573.4 CDJ68478.1 - 0.72 9.7 4.2 0.96 9.3 2.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Gag_spuma PF03276.9 CDJ68478.1 - 0.73 8.0 10.8 0.91 7.7 7.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF566 PF04484.7 CDJ68478.1 - 0.8 9.1 14.6 0.87 9.0 10.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ndc1_Nup PF09531.5 CDJ68478.1 - 1 7.6 10.8 1.1 7.6 7.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.10 CDJ68478.1 - 1.1 8.4 8.3 1.2 8.3 5.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.8 CDJ68478.1 - 1.5 8.6 13.2 1.5 8.5 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apc1 PF12859.2 CDJ68478.1 - 1.8 8.8 8.2 2.4 8.4 5.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Cwf_Cwc_15 PF04889.7 CDJ68478.1 - 1.8 8.1 9.2 2.4 7.8 6.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SpoIIIAH PF12685.2 CDJ68478.1 - 2.9 7.3 10.3 3.6 7.0 7.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Pex16 PF08610.5 CDJ68478.1 - 3 6.7 8.5 3.8 6.4 5.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ebola_NP PF05505.7 CDJ68478.1 - 3.3 5.6 9.0 3.7 5.4 6.3 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Neur_chan_memb PF02932.11 CDJ68478.1 - 3.7 7.3 6.3 4.5 7.0 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cyto_heme_lyase PF01265.12 CDJ68478.1 - 3.8 7.0 8.9 4.3 6.8 6.2 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF1675 PF07897.6 CDJ68478.1 - 5.2 6.8 10.1 6.4 6.5 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Apc15p PF05841.6 CDJ68478.1 - 5.3 7.7 15.6 7.8 7.2 10.8 1.3 1 0 0 1 1 1 0 Apc15p protein DNA_pol_viral_N PF00242.12 CDJ68478.1 - 6.6 5.6 13.7 8.1 5.3 9.5 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain MACPF PF01823.14 CDJ68478.1 - 6.8 6.3 11.2 9 5.9 7.8 1.1 1 0 0 1 1 1 0 MAC/Perforin domain Menin PF05053.8 CDJ68478.1 - 8 4.4 8.4 9.1 4.3 5.8 1.1 1 0 0 1 1 1 0 Menin UPF0104 PF03706.8 CDJ68479.1 - 0.52 9.5 25.8 9.1 5.4 18.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) Med15 PF09606.5 CDJ68480.1 - 0.0074 14.5 67.1 0.0087 14.3 46.5 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_BLLF1 PF05109.8 CDJ68480.1 - 0.51 8.2 18.1 0.58 8.0 12.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Tetraspannin PF00335.15 CDJ68480.1 - 5.7 6.1 5.3 6.8 5.9 3.7 1.2 1 0 0 1 1 1 0 Tetraspanin family IncA PF04156.9 CDJ68480.1 - 7.6 6.0 30.5 24 4.4 21.1 1.8 1 1 0 1 1 1 0 IncA protein Ribosomal_60s PF00428.14 CDJ68481.1 - 0.00091 19.5 9.1 0.0016 18.7 6.3 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein PSII_BNR PF14870.1 CDJ68481.1 - 0.00092 18.2 0.3 0.0014 17.6 0.2 1.3 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Tachylectin PF14517.1 CDJ68481.1 - 0.0022 17.3 0.0 0.89 8.8 0.0 2.7 1 1 1 2 2 2 2 Tachylectin Reg_prop PF07494.6 CDJ68481.1 - 0.018 15.0 0.3 65 4.0 0.0 4.0 4 0 0 4 4 4 0 Two component regulator propeller FCP1_C PF09309.5 CDJ68481.1 - 7.7 5.7 8.3 13 5.0 5.8 1.2 1 0 0 1 1 1 0 FCP1, C-terminal ELM2 PF01448.19 CDJ68482.1 - 0.15 12.7 0.2 0.15 12.7 0.1 1.8 2 0 0 2 2 2 0 ELM2 domain Herpes_env PF01673.13 CDJ68482.1 - 0.67 8.4 8.2 0.9 8.0 5.7 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF1501 PF07394.7 CDJ68482.1 - 4 6.1 16.0 4.8 5.9 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MRP-L28 PF09812.4 CDJ68483.1 - 0.084 12.6 5.5 0.13 12.0 3.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF3138 PF11336.3 CDJ68483.1 - 1.3 7.1 10.3 1.8 6.6 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SR-25 PF10500.4 CDJ68483.1 - 2.2 7.6 7.3 0.37 10.2 0.4 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IncA PF04156.9 CDJ68486.1 - 6.6e-06 25.8 28.8 2.7e-05 23.8 11.7 4.0 3 0 0 3 3 3 1 IncA protein Dehydrin PF00257.14 CDJ68486.1 - 0.0027 18.0 34.0 0.0039 17.5 5.4 4.6 4 0 0 4 4 4 2 Dehydrin Apt1 PF10351.4 CDJ68486.1 - 0.044 12.6 20.1 0.034 13.0 0.8 3.3 3 0 0 3 3 3 0 Golgi-body localisation protein domain zf-DHHC PF01529.15 CDJ68486.1 - 0.064 12.6 1.7 0.14 11.5 0.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Activator_LAG-3 PF11498.3 CDJ68486.1 - 0.55 8.9 64.4 0.13 11.0 32.6 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 CD20 PF04103.10 CDJ68486.1 - 0.92 9.4 7.1 0.45 10.4 0.7 2.7 2 0 0 2 2 2 0 CD20-like family Raftlin PF15250.1 CDJ68486.1 - 0.93 7.9 20.4 0.3 9.5 8.1 2.3 2 0 0 2 2 2 0 Raftlin Peptidase_S49_N PF08496.5 CDJ68486.1 - 1.9 8.2 22.5 1.8 8.3 10.8 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SR-25 PF10500.4 CDJ68486.1 - 2.6 7.4 108.0 0.028 13.8 6.3 6.4 7 0 0 7 7 7 0 Nuclear RNA-splicing-associated protein AUX_IAA PF02309.11 CDJ68486.1 - 4.4 7.0 21.6 0.39 10.4 6.5 3.4 3 0 0 3 3 3 0 AUX/IAA family GAGA_bind PF06217.7 CDJ68486.1 - 4.6 7.1 26.9 0.77 9.6 13.4 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Plasmodium_Vir PF05795.6 CDJ68486.1 - 5 6.2 10.3 2 7.5 2.2 2.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein CPSF100_C PF13299.1 CDJ68486.1 - 8.9 6.4 21.1 1.3 9.2 7.7 3.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FimP PF09766.4 CDJ68486.1 - 9.7 5.1 41.5 3.4 6.6 20.7 2.3 2 0 0 2 2 2 0 Fms-interacting protein Spore_coat_CotO PF14153.1 CDJ68486.1 - 9.9 5.5 35.1 0.021 14.2 12.4 3.2 3 0 0 3 3 3 0 Spore coat protein CotO Phostensin_N PF13916.1 CDJ68488.1 - 0.0075 16.2 4.3 1.4 8.9 0.3 2.7 2 0 0 2 2 2 2 PP1-regulatory protein, Phostensin N-terminal HEAT PF02985.17 CDJ68488.1 - 0.045 13.8 0.2 0.22 11.6 0.1 2.3 1 0 0 1 1 1 0 HEAT repeat Peptidase_M17_N PF02789.12 CDJ68488.1 - 0.12 12.1 4.0 0.94 9.2 0.6 2.4 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain HEAT_EZ PF13513.1 CDJ68488.1 - 2.1 8.9 6.5 0.28 11.7 0.3 2.7 3 1 0 3 3 3 0 HEAT-like repeat Spc97_Spc98 PF04130.8 CDJ68488.1 - 8.5 4.5 9.7 0.084 11.1 1.0 1.8 2 1 0 2 2 2 0 Spc97 / Spc98 family Spc97_Spc98 PF04130.8 CDJ68489.1 - 4e-34 117.8 0.1 1.5e-31 109.3 0.1 2.3 1 1 0 1 1 1 1 Spc97 / Spc98 family SOG2 PF10428.4 CDJ68490.1 - 0.19 10.3 16.2 0.24 10.0 11.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Dehydrin PF00257.14 CDJ68490.1 - 0.86 9.9 14.3 0.53 10.5 0.2 2.3 2 0 0 2 2 2 0 Dehydrin Macoilin PF09726.4 CDJ68490.1 - 2.6 6.2 19.5 3.2 5.9 13.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF755 PF05501.6 CDJ68490.1 - 7.7 6.5 34.6 0.36 10.8 1.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF755) DTW PF03942.10 CDJ68493.1 - 8e-09 34.9 1.7 8e-09 34.9 1.2 3.9 3 1 0 3 3 3 1 DTW domain SAGA-Tad1 PF12767.2 CDJ68493.1 - 0.12 11.9 34.1 0.8 9.3 11.2 3.2 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF755 PF05501.6 CDJ68494.1 - 0.0054 16.7 20.4 0.0054 16.7 14.2 10.8 7 2 3 11 11 11 2 Domain of unknown function (DUF755) CAF-1_p150 PF11600.3 CDJ68495.1 - 0.046 13.0 50.2 0.064 12.6 34.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PfkB PF00294.19 CDJ68496.1 - 3.9e-18 65.6 0.0 4.4e-14 52.3 0.0 2.2 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Oleosin PF01277.12 CDJ68496.1 - 0.0012 18.4 0.3 0.0012 18.4 0.2 2.6 1 1 1 2 2 2 1 Oleosin Zip PF02535.17 CDJ68496.1 - 0.015 14.3 7.6 0.022 13.7 5.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 CDJ68496.1 - 0.028 13.8 16.1 0.04 13.3 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDJ68496.1 - 0.16 9.6 19.1 0.19 9.3 13.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med5 PF08689.5 CDJ68496.1 - 0.2 9.2 11.3 0.27 8.8 7.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 Herpes_DNAp_acc PF04929.7 CDJ68496.1 - 0.37 9.6 21.6 0.53 9.1 14.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TMEM51 PF15345.1 CDJ68496.1 - 2.9 7.5 20.9 5.5 6.6 14.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4569 PF15133.1 CDJ68496.1 - 5.6 6.2 26.0 8.4 5.6 18.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4407 PF14362.1 CDJ68496.1 - 6.1 5.7 24.9 9 5.1 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SprA-related PF12118.3 CDJ68497.1 - 0.0012 18.2 27.3 0.0012 18.2 18.9 5.7 2 1 2 4 4 4 1 SprA-related family CAF-1_p150 PF11600.3 CDJ68497.1 - 0.0019 17.5 21.0 0.0019 17.5 14.6 6.1 5 1 0 6 6 6 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4201 PF13870.1 CDJ68499.1 - 6.4e-22 77.8 23.0 1e-21 77.1 16.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Ank_2 PF12796.2 CDJ68500.1 - 4e-32 110.3 12.6 2.2e-12 47.1 2.7 5.5 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDJ68500.1 - 2.1e-25 88.1 21.0 7.9e-12 45.0 0.5 5.7 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 CDJ68500.1 - 3.8e-25 86.3 27.8 0.00059 19.5 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 CDJ68500.1 - 1.3e-24 86.0 15.4 4.3e-07 30.2 0.0 6.5 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ68500.1 - 1.9e-18 64.7 13.9 0.027 14.6 0.2 7.9 7 1 0 7 7 7 5 Ankyrin repeat Sushi PF00084.15 CDJ68500.1 - 3.2e-06 27.3 0.3 5.7e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Sec63 PF02889.11 CDJ68501.1 - 7.7e-39 133.7 0.0 1.1e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 CDJ68501.1 - 6.9e-21 73.7 0.5 1.8e-20 72.3 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Dynein_light PF01221.13 CDJ68504.1 - 4.7e-23 80.9 0.0 4.8e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 zf-4CXXC_R1 PF10497.4 CDJ68504.1 - 0.00079 19.5 0.1 0.00099 19.2 0.1 1.3 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Ribosomal_L27 PF01016.14 CDJ68505.1 - 2.5e-11 43.2 0.0 6.2e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Ribosomal L27 protein GBP PF02263.14 CDJ68507.1 - 4e-12 45.7 5.5 7e-08 31.8 0.0 3.0 3 0 0 3 3 3 2 Guanylate-binding protein, N-terminal domain Ndc1_Nup PF09531.5 CDJ68507.1 - 0.00059 18.3 1.1 0.00059 18.3 0.7 5.4 2 2 1 4 4 4 2 Nucleoporin protein Ndc1-Nup SLBP_RNA_bind PF15247.1 CDJ68508.1 - 4.4e-17 61.6 1.9 4.4e-17 61.6 1.3 3.4 4 0 0 4 4 4 1 Histone RNA hairpin-binding protein RNA-binding domain SR-25 PF10500.4 CDJ68508.1 - 2e-05 24.1 19.6 2e-05 24.1 13.6 5.1 5 1 0 5 5 5 2 Nuclear RNA-splicing-associated protein GP40 PF11025.3 CDJ68508.1 - 3.2 7.2 8.6 0.056 13.0 0.8 1.8 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium Plasmodium_Vir PF05795.6 CDJ68508.1 - 4.9 6.2 10.4 7.9 5.5 0.1 2.9 2 1 0 2 2 2 0 Plasmodium vivax Vir protein CPW_WPC PF09717.5 CDJ68509.1 - 3.1e-11 43.7 5.2 5.9e-05 23.6 0.2 3.5 3 1 0 3 3 3 2 Plasmodium falciparum domain of unknown function (CPW_WPC) Tme5_EGF_like PF09064.5 CDJ68509.1 - 2 8.0 11.2 1.4 8.5 1.6 2.9 2 1 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like DUF2486 PF10667.4 CDJ68511.1 - 3.1 8.2 32.3 5.2 7.5 22.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Prefoldin_2 PF01920.15 CDJ68512.1 - 5.3e-05 22.9 4.0 7.5e-05 22.4 2.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit 2-Hacid_dh_C PF02826.14 CDJ68512.1 - 0.0013 17.9 0.1 0.0014 17.8 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain mRNA_cap_enzyme PF01331.14 CDJ68512.1 - 0.042 13.5 0.0 0.047 13.3 0.0 1.0 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Pex14_N PF04695.8 CDJ68512.1 - 0.064 13.3 2.6 0.078 13.0 1.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.6 CDJ68512.1 - 0.072 12.4 4.9 0.11 11.8 3.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PAT1 PF09770.4 CDJ68512.1 - 0.17 10.1 8.8 0.13 10.4 6.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WES_acyltransf PF03007.11 CDJ68512.1 - 0.22 11.0 1.9 0.23 10.9 1.3 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Spt20 PF12090.3 CDJ68512.1 - 1.1 8.5 4.4 1.3 8.3 3.0 1.1 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.11 CDJ68512.1 - 4.4 6.0 10.1 5.4 5.7 7.0 1.2 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.3 CDJ68512.1 - 6.2 5.9 13.8 7.8 5.6 9.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DivIC PF04977.10 CDJ68512.1 - 8.3 5.9 11.5 12 5.4 8.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Securin PF04856.8 CDJ68513.1 - 0.44 10.2 7.6 1.2 8.7 5.3 1.8 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor CDC45 PF02724.9 CDJ68513.1 - 0.74 7.7 12.3 0.72 7.8 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein PRCC PF10253.4 CDJ68513.1 - 0.81 10.3 26.7 1.1 9.9 18.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Plasmodium_Vir PF05795.6 CDJ68513.1 - 1.5 7.9 5.0 1.4 8.0 3.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Utp14 PF04615.8 CDJ68513.1 - 2.2 6.3 23.9 2.5 6.1 16.6 1.0 1 0 0 1 1 1 0 Utp14 protein Kei1 PF08552.6 CDJ68513.1 - 2.6 7.6 8.0 2.6 7.6 5.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 eIF3_subunit PF08597.5 CDJ68513.1 - 3 7.3 17.8 3.4 7.1 12.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DDRGK PF09756.4 CDJ68513.1 - 3.6 6.9 25.9 4.5 6.6 18.0 1.3 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.3 CDJ68513.1 - 4.4 5.9 18.2 4.6 5.8 12.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AP-5_subunit_s1 PF15001.1 CDJ68513.1 - 7.3 6.4 17.0 12 5.7 11.8 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 zf-RING_2 PF13639.1 CDJ68514.1 - 2e-06 27.5 13.0 5.3e-06 26.1 9.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDJ68514.1 - 5.9e-06 26.2 12.8 1.6e-05 24.7 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDJ68514.1 - 8.6e-06 25.3 8.9 2.3e-05 23.9 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ68514.1 - 6.3e-05 22.6 10.2 6.3e-05 22.6 7.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDJ68514.1 - 6.3e-05 22.5 11.3 6.3e-05 22.5 7.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDJ68514.1 - 0.0031 17.3 14.6 0.011 15.5 10.1 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.10 CDJ68514.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_UBOX PF13445.1 CDJ68514.1 - 0.07 12.8 9.2 0.2 11.4 6.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Peptidase_C97 PF05903.9 CDJ68514.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain RSF PF14876.1 CDJ68514.1 - 0.29 9.8 2.0 0.71 8.6 0.1 2.1 2 0 0 2 2 2 0 Respiratory growth transcriptional regulator WTX PF09422.5 CDJ68515.1 - 6 5.7 21.2 7.3 5.4 14.7 1.0 1 0 0 1 1 1 0 WTX protein CDC27 PF09507.5 CDJ68515.1 - 6.6 5.8 29.1 7.8 5.5 20.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TMEM51 PF15345.1 CDJ68516.1 - 1.7 8.3 9.5 2.7 7.6 6.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 FDF PF09532.5 CDJ68516.1 - 5 7.7 8.6 10 6.7 6.0 1.5 1 1 0 1 1 1 0 FDF domain DUF3446 PF11928.3 CDJ68517.1 - 4.2 7.6 13.1 4.3 7.6 0.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Med15 PF09606.5 CDJ68518.1 - 0.018 13.2 48.3 0.019 13.1 33.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF677 PF05055.7 CDJ68518.1 - 0.018 13.7 8.6 0.027 13.1 5.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Esterase PF00756.15 CDJ68518.1 - 0.084 12.2 7.7 0.098 12.0 5.3 1.1 1 0 0 1 1 1 0 Putative esterase PAT1 PF09770.4 CDJ68518.1 - 5.4 5.1 37.4 6.6 4.8 25.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MRP-S31 PF15433.1 CDJ68518.1 - 9.8 5.4 28.4 14 4.9 19.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TPR_1 PF00515.23 CDJ68519.1 - 6.5e-06 25.5 4.9 0.0085 15.6 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ68519.1 - 0.00056 20.5 0.4 0.00056 20.5 0.3 5.8 4 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ68519.1 - 0.00061 20.0 1.7 0.00061 20.0 1.2 5.1 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ68519.1 - 0.0016 18.1 0.1 0.0016 18.1 0.1 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat Corona_nucleoca PF00937.13 CDJ68519.1 - 0.026 13.4 8.0 0.046 12.6 5.6 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RAP1 PF07218.6 CDJ68519.1 - 0.035 12.2 4.4 0.047 11.8 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2217 PF10265.4 CDJ68519.1 - 0.098 11.4 11.1 0.13 11.0 7.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Suc_Fer-like PF06999.7 CDJ68519.1 - 0.12 12.3 2.7 0.28 11.1 1.9 1.6 1 0 0 1 1 1 0 Sucrase/ferredoxin-like RNA_pol_Rpb4 PF03874.11 CDJ68519.1 - 4.6 7.2 8.1 9.7 6.2 0.0 3.3 2 2 1 3 3 3 0 RNA polymerase Rpb4 Apc3 PF12895.2 CDJ68519.1 - 5.8 7.1 24.2 0.025 14.7 5.7 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 GDI PF00996.13 CDJ68520.1 - 0.12 10.6 0.1 0.17 10.1 0.1 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Sporozoite_P67 PF05642.6 CDJ68521.1 - 0.54 8.0 9.0 0.67 7.7 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 CDJ68521.1 - 0.92 7.5 20.0 1.2 7.1 13.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1517 PF07466.6 CDJ68521.1 - 5.4 5.9 10.1 40 3.0 7.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) CAP_N PF01213.14 CDJ68521.1 - 5.7 6.1 8.8 1.1 8.4 2.5 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Secretin_N_2 PF07655.8 CDJ68521.1 - 5.8 7.3 20.1 10 6.5 13.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain SAPS PF04499.10 CDJ68522.1 - 0.068 11.7 0.3 0.089 11.4 0.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-HIT PF04438.11 CDJ68522.1 - 0.087 12.4 14.5 0.15 11.6 10.1 1.4 1 0 0 1 1 1 0 HIT zinc finger BAF1_ABF1 PF04684.8 CDJ68522.1 - 0.57 8.9 18.0 0.82 8.4 12.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FCP1_C PF09309.5 CDJ68522.1 - 1.7 7.8 14.5 0.54 9.5 4.6 2.2 2 0 0 2 2 2 0 FCP1, C-terminal CDK2AP PF09806.4 CDJ68522.1 - 4 7.6 16.4 2.9 8.0 8.5 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF966 PF06136.8 CDJ68522.1 - 4.1 6.7 9.7 3 7.1 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Activator_LAG-3 PF11498.3 CDJ68522.1 - 4.1 6.0 29.6 0.9 8.2 16.0 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PAPS_reduct PF01507.14 CDJ68523.1 - 5.7e-19 68.5 7.0 1.7e-11 44.2 0.0 3.8 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family DUF2413 PF10310.4 CDJ68523.1 - 0.19 10.4 52.2 0.031 13.0 16.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) NAD_synthase PF02540.12 CDJ68523.1 - 1.6 7.5 10.4 0.015 14.2 1.8 1.5 2 0 0 2 2 2 0 NAD synthase Suf PF05843.9 CDJ68524.1 - 0.046 13.4 4.0 0.064 12.9 2.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) OAD_gamma PF04277.8 CDJ68524.1 - 0.061 13.6 0.3 0.061 13.6 0.2 3.2 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Nop14 PF04147.7 CDJ68525.1 - 0.0023 15.9 3.0 0.002 16.1 2.1 1.1 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.7 CDJ68525.1 - 0.019 14.2 11.3 0.023 13.9 7.8 1.1 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.5 CDJ68525.1 - 0.019 15.5 19.2 0.019 15.5 13.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.7 CDJ68525.1 - 0.024 13.9 4.1 0.029 13.6 2.9 1.3 1 0 0 1 1 1 0 SDA1 Nucleoplasmin PF03066.10 CDJ68525.1 - 0.027 13.9 8.6 0.046 13.2 6.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CDJ68525.1 - 0.11 12.6 10.9 0.18 12.0 7.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.1 CDJ68525.1 - 0.35 10.0 4.6 0.48 9.5 3.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PBP1_TM PF14812.1 CDJ68525.1 - 0.89 9.8 13.7 1.7 9.0 9.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.7 CDJ68525.1 - 1.4 8.6 12.3 1.9 8.1 8.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Bromodomain PF00439.20 CDJ68526.1 - 2.8e-06 27.1 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DEAD PF00270.24 CDJ68527.1 - 1.5e-27 96.1 0.0 2.4e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CDJ68527.1 - 8.7e-10 38.0 0.0 1.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CDJ68527.1 - 0.074 12.8 1.2 0.079 12.7 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF566 PF04484.7 CDJ68527.1 - 0.84 9.0 13.2 1.3 8.4 9.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Spore_coat_CotO PF14153.1 CDJ68527.1 - 0.85 9.0 9.7 1.3 8.4 6.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Cwf_Cwc_15 PF04889.7 CDJ68527.1 - 1.3 8.6 11.2 2 8.0 7.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pex14_N PF04695.8 CDJ68527.1 - 3.8 7.5 10.4 8 6.5 7.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3138 PF11336.3 CDJ68527.1 - 8.9 4.3 10.8 12 3.9 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Trichoplein PF13868.1 CDJ68528.1 - 6.8e-26 90.4 151.5 6.8e-26 90.4 105.0 2.2 1 1 0 2 2 2 1 Tumour suppressor, Mitostatin APC_CDC26 PF10471.4 CDJ68529.1 - 0.23 12.1 9.5 0.34 11.6 6.6 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 ELO PF01151.13 CDJ68530.1 - 2.1e-48 164.8 22.1 2.8e-48 164.4 15.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Kelch_4 PF13418.1 CDJ68531.1 - 0.0032 17.1 0.9 0.0061 16.3 0.6 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ68531.1 - 0.0089 15.9 0.4 0.031 14.2 0.3 2.0 1 0 0 1 1 1 1 Kelch motif SAGA-Tad1 PF12767.2 CDJ68531.1 - 0.2 11.2 14.2 0.31 10.6 9.9 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2217 PF10265.4 CDJ68531.1 - 1.7 7.3 15.4 2.5 6.7 10.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MRP-S31 PF15433.1 CDJ68531.1 - 4.1 6.7 14.7 5.2 6.4 9.5 1.6 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Na_trans_assoc PF06512.8 CDJ68531.1 - 4.3 7.2 8.2 5.9 6.7 5.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated PAT1 PF09770.4 CDJ68531.1 - 5.8 5.0 25.5 8.9 4.4 17.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDJ68531.1 - 8.1 4.5 23.7 10 4.2 16.5 1.2 1 0 0 1 1 1 0 Transmembrane protein CECR6_TMEM121 PF14997.1 CDJ68532.1 - 6.9e-07 29.0 1.4 9.3e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 CECR6/TMEM121 family Tmem26 PF09772.4 CDJ68532.1 - 0.023 13.9 0.7 0.023 13.9 0.5 1.9 2 0 0 2 2 2 0 Transmembrane protein 26 DUF4355 PF14265.1 CDJ68534.1 - 1.3 8.9 11.4 0.032 14.1 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) IER PF05760.7 CDJ68534.1 - 1.3 8.8 20.1 1.5 8.6 13.9 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Ribosomal_60s PF00428.14 CDJ68535.1 - 0.02 15.2 4.5 0.022 15.1 3.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein CDK2AP PF09806.4 CDJ68535.1 - 0.11 12.6 21.2 0.13 12.4 14.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Med3 PF11593.3 CDJ68535.1 - 0.26 10.5 14.3 0.26 10.4 9.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-C4H2 PF10146.4 CDJ68535.1 - 0.48 10.3 4.8 0.5 10.3 3.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein L1R_F9L PF02442.12 CDJ68535.1 - 0.84 9.0 10.7 0.91 8.9 7.4 1.0 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses PepSY_2 PF13670.1 CDJ68535.1 - 2 8.3 5.5 2.7 7.9 3.8 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain RIC3 PF15361.1 CDJ68535.1 - 2.4 8.3 6.3 2.9 8.1 4.3 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 TFIIA PF03153.8 CDJ68535.1 - 2.6 7.8 10.3 2.5 7.8 7.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2360 PF10152.4 CDJ68535.1 - 2.8 8.2 7.7 3.1 8.0 5.3 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Opi1 PF08618.5 CDJ68535.1 - 6.3 5.6 21.9 6.2 5.6 15.2 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 AUX_IAA PF02309.11 CDJ68535.1 - 7.1 6.3 6.7 8 6.1 4.7 1.0 1 0 0 1 1 1 0 AUX/IAA family Suf PF05843.9 CDJ68535.1 - 7.2 6.2 7.5 7.7 6.1 5.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CAML PF14963.1 CDJ68535.1 - 8.3 5.6 8.5 9.2 5.5 5.9 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Rifin_STEVOR PF02009.11 CDJ68535.1 - 8.7 5.8 7.9 10 5.6 5.5 1.0 1 0 0 1 1 1 0 Rifin/stevor family Suf PF05843.9 CDJ68536.1 - 0.014 15.1 11.2 0.018 14.7 7.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ68536.1 - 0.053 12.5 22.8 0.076 12.0 15.8 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF912 PF06024.7 CDJ68536.1 - 0.1 12.6 4.4 0.23 11.5 3.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spt20 PF12090.3 CDJ68536.1 - 0.33 10.2 14.3 0.12 11.7 7.9 1.7 2 0 0 2 2 2 0 Spt20 family AAA_23 PF13476.1 CDJ68536.1 - 0.46 10.7 22.2 0.69 10.1 15.4 1.3 1 0 0 1 1 1 0 AAA domain DHQS PF01959.11 CDJ68536.1 - 1.8 7.1 6.9 0.081 11.6 0.3 1.8 1 1 1 2 2 2 0 3-dehydroquinate synthase (EC 4.6.1.3) AIF_C PF14721.1 CDJ68536.1 - 3 8.1 6.7 7.7 6.7 4.7 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex14_N PF04695.8 CDJ68536.1 - 5.6 7.0 17.0 16 5.5 11.8 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.10 CDJ68536.1 - 6 6.9 9.6 7.9 6.5 3.1 2.4 2 0 0 2 2 2 0 Ctr copper transporter family IncA PF04156.9 CDJ68537.1 - 2e-05 24.2 16.0 3.5e-05 23.4 11.1 1.3 1 0 0 1 1 1 1 IncA protein TraT PF05818.7 CDJ68537.1 - 0.0036 16.7 16.2 0.0036 16.7 11.2 2.5 2 1 0 2 2 1 1 Enterobacterial TraT complement resistance protein TMEM51 PF15345.1 CDJ68537.1 - 0.0069 16.1 9.1 0.0069 16.1 6.3 2.2 2 0 0 2 2 2 1 Transmembrane protein 51 Acetyltransf_1 PF00583.19 CDJ68537.1 - 0.036 14.1 0.1 0.088 12.8 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Cellulose_synt PF03552.9 CDJ68537.1 - 0.11 10.7 5.7 0.14 10.4 4.0 1.2 1 0 0 1 1 1 0 Cellulose synthase Folate_carrier PF01770.13 CDJ68537.1 - 0.22 9.9 9.5 0.54 8.7 6.6 1.6 1 0 0 1 1 1 0 Reduced folate carrier zf-DHHC PF01529.15 CDJ68537.1 - 0.26 10.6 5.7 0.55 9.6 3.9 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase YjgP_YjgQ PF03739.9 CDJ68537.1 - 0.52 8.9 3.9 0.53 8.9 2.7 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2232 PF09991.4 CDJ68537.1 - 0.7 8.8 7.2 1.1 8.1 5.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FPN1 PF06963.7 CDJ68537.1 - 0.85 7.9 5.6 1.5 7.1 3.9 1.4 1 0 0 1 1 1 0 Ferroportin1 (FPN1) FHIPEP PF00771.15 CDJ68537.1 - 0.89 7.8 14.9 1.1 7.5 10.3 1.2 1 0 0 1 1 1 0 FHIPEP family Nucleoside_tran PF01733.13 CDJ68537.1 - 0.93 8.5 2.8 1.5 7.9 2.0 1.3 1 0 0 1 1 1 0 Nucleoside transporter SID-1_RNA_chan PF13965.1 CDJ68537.1 - 1 7.4 6.2 1.8 6.6 4.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4446 PF14584.1 CDJ68537.1 - 1.3 8.8 8.2 2.1 8.1 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) OSTbeta PF15048.1 CDJ68537.1 - 2.1 8.4 12.1 0.14 12.2 4.5 1.9 2 1 0 2 2 2 0 Organic solute transporter subunit beta protein PAT1 PF09770.4 CDJ68537.1 - 2.2 6.4 49.2 0.04 12.1 26.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Gag_spuma PF03276.9 CDJ68537.1 - 2.4 6.3 39.5 0.075 11.3 17.4 2.3 2 0 0 2 2 2 0 Spumavirus gag protein Herpes_glycop PF01528.11 CDJ68537.1 - 2.5 6.6 5.4 4.6 5.8 3.8 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Neur_chan_memb PF02932.11 CDJ68537.1 - 2.6 7.8 24.8 0.024 14.5 7.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region 5_nucleotid PF05761.9 CDJ68537.1 - 3.3 6.1 14.0 4.7 5.6 9.7 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF2561 PF10812.3 CDJ68537.1 - 3.4 7.2 22.1 0.034 13.7 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Anoctamin PF04547.7 CDJ68537.1 - 5.3 5.5 9.6 7.4 5.1 6.7 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Pex16 PF08610.5 CDJ68537.1 - 6.3 5.6 21.4 0.022 13.7 7.6 1.9 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Dala_Dala_lig_N PF01820.16 CDJ68537.1 - 7.7 6.8 12.2 0.33 11.2 3.3 2.3 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus PIH1 PF08190.7 CDJ68537.1 - 9.8 5.5 32.1 0.45 9.9 11.2 2.1 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Activator_LAG-3 PF11498.3 CDJ68539.1 - 0.0038 16.0 25.9 0.0038 16.0 17.9 5.3 4 1 1 5 5 5 2 Transcriptional activator LAG-3 YjgP_YjgQ PF03739.9 CDJ68540.1 - 0.16 10.7 11.6 0.23 10.1 8.0 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PAT1 PF09770.4 CDJ68540.1 - 5.9 5.0 82.2 11 4.1 57.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDJ68542.1 - 0.0013 17.5 8.8 0.0014 17.4 6.1 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 RAB3GAP2_N PF14655.1 CDJ68542.1 - 0.0015 17.6 2.4 0.0019 17.3 1.7 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDJ68542.1 - 0.081 12.6 3.1 0.086 12.5 2.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ68542.1 - 0.13 12.1 10.6 0.14 12.0 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDJ68542.1 - 0.13 10.4 17.1 0.16 10.1 11.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ68542.1 - 0.55 8.4 11.9 0.61 8.2 8.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2868 PF11067.3 CDJ68542.1 - 1.4 7.9 12.7 1.9 7.5 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) MSP1_C PF07462.6 CDJ68542.1 - 1.5 7.1 6.3 2.1 6.6 4.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Phostensin_N PF13916.1 CDJ68543.1 - 0.019 14.9 4.6 0.023 14.6 3.2 1.3 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Med15 PF09606.5 CDJ68543.1 - 0.077 11.1 12.5 0.073 11.2 8.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDJ68543.1 - 0.12 11.1 17.1 0.13 10.9 11.8 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FimP PF09766.4 CDJ68543.1 - 0.29 10.1 6.1 0.3 10.1 4.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein Androgen_recep PF02166.11 CDJ68543.1 - 0.65 8.8 7.3 0.71 8.6 5.1 1.1 1 0 0 1 1 1 0 Androgen receptor DUF4175 PF13779.1 CDJ68543.1 - 2.7 5.5 11.2 2.8 5.5 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ribosomal_60s PF00428.14 CDJ68544.1 - 0.0013 19.0 4.6 0.0013 19.0 3.2 7.0 6 1 1 7 7 7 1 60s Acidic ribosomal protein PRP3 PF08572.5 CDJ68544.1 - 0.012 14.9 0.4 0.012 14.9 0.3 7.0 8 0 0 8 8 8 0 pre-mRNA processing factor 3 (PRP3) PigN PF04987.9 CDJ68545.1 - 9.2 4.7 9.9 0.51 8.9 2.0 2.2 2 1 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) Phos_pyr_kin PF08543.7 CDJ68546.1 - 2e-07 30.4 0.2 6.7e-05 22.1 0.0 3.1 2 1 1 3 3 3 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CDJ68546.1 - 7.2e-07 28.6 1.6 0.0013 17.9 0.0 3.0 2 2 0 2 2 2 2 pfkB family carbohydrate kinase DUF2361 PF10153.4 CDJ68546.1 - 0.062 13.5 1.6 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) Hydrolase PF00702.21 CDJ68546.1 - 0.62 10.4 7.9 1.3 9.4 5.3 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2910 PF11139.3 CDJ68546.1 - 0.99 8.4 10.4 0.87 8.6 2.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) SR-25 PF10500.4 CDJ68546.1 - 7.4 5.9 16.9 0.72 9.2 6.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF947 PF06102.7 CDJ68547.1 - 0.042 13.6 6.1 0.055 13.2 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF947) MCPVI PF02993.9 CDJ68547.1 - 0.39 10.8 9.2 0.41 10.7 6.4 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Viral_P18 PF04521.8 CDJ68547.1 - 0.66 9.4 5.1 1.1 8.7 3.6 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein LCD1 PF09798.4 CDJ68547.1 - 0.74 7.7 3.2 0.8 7.6 2.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3373 PF11853.3 CDJ68547.1 - 1.3 7.4 5.0 1.3 7.5 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) ERM PF00769.14 CDJ68547.1 - 1.6 8.2 10.7 2.1 7.7 7.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Cytadhesin_P30 PF07271.6 CDJ68547.1 - 3 7.0 14.4 3.8 6.7 10.0 1.0 1 0 0 1 1 1 0 Cytadhesin P30/P32 UPF0565 PF10561.4 CDJ68547.1 - 3.1 6.6 6.0 3.4 6.4 4.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 bZIP_Maf PF03131.12 CDJ68547.1 - 4.4 7.6 12.1 2.4 8.5 7.0 1.5 2 0 0 2 2 2 0 bZIP Maf transcription factor DLIC PF05783.6 CDJ68547.1 - 6.5 5.2 6.6 7.1 5.1 4.5 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) YppG PF14179.1 CDJ68547.1 - 9 6.9 12.0 11 6.6 8.3 1.1 1 0 0 1 1 1 0 YppG-like protein DUF912 PF06024.7 CDJ68548.1 - 0.015 15.3 16.9 0.18 11.8 0.4 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S49_N PF08496.5 CDJ68548.1 - 0.018 14.8 16.4 0.13 12.0 7.3 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CAF-1_p150 PF11600.3 CDJ68548.1 - 7.9 5.7 47.3 0.018 14.4 19.9 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNB PF00773.14 CDJ68549.1 - 1.7e-21 76.8 1.8 2.2e-21 76.5 1.3 1.1 1 0 0 1 1 1 1 RNB domain Med15 PF09606.5 CDJ68549.1 - 0.00034 18.9 22.7 0.00043 18.6 15.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 CDJ68549.1 - 0.0036 15.6 11.2 0.0038 15.5 7.8 1.0 1 0 0 1 1 1 1 Transmembrane protein SPX PF03105.14 CDJ68549.1 - 0.0099 15.6 5.9 0.013 15.2 4.1 1.1 1 0 0 1 1 1 1 SPX domain RAP1 PF07218.6 CDJ68549.1 - 0.025 12.6 6.5 0.025 12.7 4.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol_viral_N PF00242.12 CDJ68549.1 - 0.032 13.2 10.4 0.038 13.0 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain BUD22 PF09073.5 CDJ68549.1 - 0.038 13.0 12.2 0.063 12.3 8.4 1.3 1 0 0 1 1 1 0 BUD22 Neur_chan_memb PF02932.11 CDJ68549.1 - 0.069 13.0 1.9 0.082 12.7 1.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1183 PF06682.7 CDJ68549.1 - 0.13 11.8 11.5 0.18 11.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Plasmodium_Vir PF05795.6 CDJ68549.1 - 0.14 11.3 3.1 0.18 10.9 2.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FimP PF09766.4 CDJ68549.1 - 0.18 10.8 8.7 0.22 10.5 6.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Na_trans_assoc PF06512.8 CDJ68549.1 - 0.23 11.3 5.4 0.31 10.9 3.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated TAF4 PF05236.9 CDJ68549.1 - 0.24 10.6 12.6 0.38 10.0 8.7 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4175 PF13779.1 CDJ68549.1 - 0.35 8.5 15.9 0.41 8.3 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FNIP_N PF14636.1 CDJ68549.1 - 0.43 11.0 12.2 2.1 8.7 2.0 2.2 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Serinc PF03348.10 CDJ68549.1 - 1 8.0 3.2 1.4 7.5 2.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF508 PF04370.7 CDJ68549.1 - 1.8 8.1 7.9 3 7.4 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF4557 PF15101.1 CDJ68549.1 - 3.6 7.3 13.6 1.2 8.9 7.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Pex14_N PF04695.8 CDJ68549.1 - 3.7 7.5 26.7 0.47 10.5 4.6 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.2 CDJ68549.1 - 4.4 4.8 9.9 6.4 4.3 6.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATAD4 PF15321.1 CDJ68549.1 - 4.8 8.2 12.6 8.1 7.5 4.7 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 PHD_3 PF13922.1 CDJ68549.1 - 5 7.4 11.1 11 6.3 7.7 1.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PsbW PF07123.7 CDJ68549.1 - 9.6 6.2 8.6 1.4 8.9 2.4 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) SR-25 PF10500.4 CDJ68550.1 - 0.0094 15.4 32.1 0.22 10.9 7.9 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Cadherin_C PF01049.12 CDJ68550.1 - 0.043 13.8 0.3 0.043 13.8 0.2 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic region CAF-1_p150 PF11600.3 CDJ68550.1 - 0.084 12.2 23.8 0.5 9.6 3.5 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAM60A PF15396.1 CDJ68550.1 - 0.14 11.8 16.9 0.88 9.2 1.2 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF3886 PF13025.1 CDJ68550.1 - 0.3 11.0 21.3 0.37 10.7 5.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) Hamartin PF04388.7 CDJ68550.1 - 0.39 9.3 22.2 0.54 8.8 15.4 1.2 1 0 0 1 1 1 0 Hamartin protein PBP1_TM PF14812.1 CDJ68550.1 - 0.75 10.1 3.9 0.96 9.8 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SprA-related PF12118.3 CDJ68550.1 - 1.5 8.0 55.9 3.1 7.0 12.6 2.3 2 0 0 2 2 2 0 SprA-related family DUF913 PF06025.7 CDJ68550.1 - 1.7 7.3 14.7 1.7 7.3 1.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CD20 PF04103.10 CDJ68550.1 - 2.5 8.0 7.3 11 5.9 1.4 2.3 2 0 0 2 2 2 0 CD20-like family RR_TM4-6 PF06459.7 CDJ68550.1 - 3.1 7.5 21.6 2.9 7.7 6.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Folate_carrier PF01770.13 CDJ68550.1 - 3.6 5.9 9.6 0.52 8.7 1.4 2.1 2 0 0 2 2 2 0 Reduced folate carrier Pex14_N PF04695.8 CDJ68550.1 - 4.1 7.4 48.8 0.05 13.6 10.8 2.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spc24 PF08286.6 CDJ68550.1 - 5.1 6.8 15.5 0.96 9.1 6.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FimP PF09766.4 CDJ68550.1 - 5.4 5.9 31.5 0.82 8.6 10.8 2.2 2 0 0 2 2 2 0 Fms-interacting protein FPN1 PF06963.7 CDJ68550.1 - 7.8 4.7 9.6 2.6 6.3 1.3 2.1 2 0 0 2 2 2 0 Ferroportin1 (FPN1) ERF PF04404.7 CDJ68551.1 - 0.025 14.1 11.0 0.035 13.6 7.6 1.2 1 0 0 1 1 1 0 ERF superfamily TFIIA PF03153.8 CDJ68551.1 - 4.4 7.0 18.0 4.6 7.0 12.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMBR1 PF04791.11 CDJ68553.1 - 0.36 9.3 6.7 0.54 8.7 4.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Herpes_UL87 PF03043.9 CDJ68553.1 - 1.9 6.7 21.4 2.8 6.2 14.8 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family SR-25 PF10500.4 CDJ68554.1 - 4.4e-05 23.0 5.5 4.4e-05 23.0 3.8 6.5 5 3 2 7 7 7 1 Nuclear RNA-splicing-associated protein AP2 PF00847.15 CDJ68554.1 - 0.0003 20.8 0.0 0.0003 20.8 0.0 5.2 6 0 0 6 6 6 1 AP2 domain Spt20 PF12090.3 CDJ68554.1 - 4 6.7 8.1 2.3 7.5 1.2 2.7 2 0 0 2 2 2 0 Spt20 family Frag1 PF10277.4 CDJ68555.1 - 0.072 12.5 1.8 0.1 12.0 1.2 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family HMA PF00403.21 CDJ68556.1 - 9.4e-08 32.0 0.4 1.4e-06 28.3 0.0 2.7 2 1 1 3 3 3 1 Heavy-metal-associated domain E1-E2_ATPase PF00122.15 CDJ68557.1 - 2.7e-20 72.3 2.1 1.2e-19 70.3 1.4 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDJ68557.1 - 0.013 15.8 0.6 0.09 13.1 0.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDJ68558.1 - 2.3e-19 70.6 0.0 3e-18 67.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ68558.1 - 1.2e-07 32.0 0.0 3e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDJ68558.1 - 0.0021 17.6 0.0 0.99 8.9 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ArfGap PF01412.13 CDJ68559.1 - 4.9e-12 45.6 6.3 1.1e-08 34.8 0.0 3.1 3 1 1 4 4 4 2 Putative GTPase activating protein for Arf CIAPIN1 PF05093.8 CDJ68559.1 - 0.62 10.1 3.4 2.8 8.0 0.1 2.5 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pex14_N PF04695.8 CDJ68559.1 - 6.5 6.8 15.2 2 8.4 2.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Striatin PF08232.7 CDJ68559.1 - 6.8 7.0 10.7 0.5 10.6 3.0 2.0 2 0 0 2 2 2 0 Striatin family K_channel_TID PF07941.6 CDJ68559.1 - 9.9 6.4 17.9 6.3 7.1 6.1 3.0 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Med15 PF09606.5 CDJ68560.1 - 0.73 7.9 47.6 0.0049 15.1 27.2 1.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SNARE_assoc PF09335.6 CDJ68563.1 - 4.1e-18 65.7 8.2 4.1e-18 65.7 5.7 2.7 3 1 0 3 3 3 1 SNARE associated Golgi protein Pex14_N PF04695.8 CDJ68563.1 - 0.0018 18.2 0.9 0.0039 17.2 0.6 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2407_C PF13373.1 CDJ68563.1 - 0.0026 17.7 1.3 0.0046 16.8 0.3 1.9 1 1 0 1 1 1 1 DUF2407 C-terminal domain FimP PF09766.4 CDJ68563.1 - 0.0036 16.4 1.2 0.0046 16.0 0.8 1.1 1 0 0 1 1 1 1 Fms-interacting protein OCIA PF07051.6 CDJ68563.1 - 0.037 13.4 0.2 0.076 12.4 0.1 1.5 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) PvlArgDC PF01862.11 CDJ68563.1 - 0.083 12.4 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) AIF_C PF14721.1 CDJ68563.1 - 0.11 12.7 0.1 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Suf PF05843.9 CDJ68563.1 - 0.2 11.3 2.9 0.29 10.8 2.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF912 PF06024.7 CDJ68563.1 - 0.52 10.3 0.1 0.52 10.3 0.0 1.9 2 0 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Med15 PF09606.5 CDJ68563.1 - 0.54 8.3 17.1 0.71 7.9 11.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4106 PF13388.1 CDJ68563.1 - 3.8 6.3 9.6 5.2 5.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Androgen_recep PF02166.11 CDJ68563.1 - 7.5 5.2 9.1 11 4.7 6.3 1.1 1 0 0 1 1 1 0 Androgen receptor Herpes_BLLF1 PF05109.8 CDJ68565.1 - 0.078 10.9 5.5 0.094 10.6 3.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) CBFD_NFYB_HMF PF00808.18 CDJ68566.1 - 1.7e-05 24.7 0.6 4.8e-05 23.3 0.4 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CDJ68566.1 - 0.00073 19.6 1.2 0.0016 18.5 0.8 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SR-25 PF10500.4 CDJ68566.1 - 0.0025 17.3 7.3 0.0025 17.3 5.0 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ68566.1 - 0.004 16.2 2.8 0.0062 15.6 1.9 1.2 1 0 0 1 1 1 1 Fms-interacting protein SGT1 PF07093.6 CDJ68566.1 - 0.011 14.1 2.9 0.012 14.0 2.0 1.2 1 0 0 1 1 1 0 SGT1 protein Spt20 PF12090.3 CDJ68566.1 - 0.024 14.0 0.6 0.038 13.3 0.4 1.3 1 0 0 1 1 1 0 Spt20 family Rxt3 PF08642.5 CDJ68566.1 - 0.035 14.3 0.3 0.083 13.1 0.2 1.6 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF31 PF01732.11 CDJ68566.1 - 0.048 12.9 0.1 0.073 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Serinc PF03348.10 CDJ68566.1 - 0.7 8.5 2.3 1 8.0 1.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3684 PF12449.3 CDJ68566.1 - 0.72 7.3 8.2 0.028 12.0 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3684) PHD_3 PF13922.1 CDJ68566.1 - 0.99 9.6 5.1 4.1 7.7 3.5 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx ATAD4 PF15321.1 CDJ68566.1 - 1.2 10.1 11.1 2.7 9.0 1.7 3.1 3 0 0 3 3 3 0 ATPase family AAA domain containing 4 DivIC PF04977.10 CDJ68566.1 - 3.8 7.0 11.6 9.9 5.7 8.0 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF3446 PF11928.3 CDJ68566.1 - 4.2 7.6 28.1 2.3 8.4 2.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Tom22 PF04281.8 CDJ68566.1 - 5.1 6.6 15.1 0.7 9.4 3.1 3.2 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Dehydrin PF00257.14 CDJ68566.1 - 5.9 7.2 16.9 9.5 6.5 6.2 2.6 2 1 0 2 2 2 0 Dehydrin DUF788 PF05620.6 CDJ68566.1 - 6.4 6.5 5.9 12 5.6 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Arm PF00514.18 CDJ68568.1 - 2.4e-87 284.1 18.3 1.6e-14 53.1 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDJ68568.1 - 4.7e-25 87.6 5.5 7.3e-09 35.8 0.0 6.2 2 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CDJ68568.1 - 1.4e-21 76.3 12.7 1.5e-08 34.8 0.0 6.9 6 3 2 8 8 8 4 HEAT-like repeat HEAT PF02985.17 CDJ68568.1 - 2.7e-15 54.9 4.4 1e-05 25.1 0.0 7.0 7 1 1 8 8 8 3 HEAT repeat IBB PF01749.15 CDJ68568.1 - 9.7e-09 35.2 5.2 2.1e-08 34.2 3.6 1.5 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.15 CDJ68568.1 - 3.4e-05 22.3 0.0 0.014 13.7 0.0 3.1 2 1 1 3 3 3 1 Adaptin N terminal region Arm_2 PF04826.8 CDJ68568.1 - 8e-05 21.8 0.0 0.23 10.5 0.0 2.9 1 1 2 3 3 3 3 Armadillo-like V-ATPase_H_C PF11698.3 CDJ68568.1 - 0.00017 21.5 0.0 0.3 11.0 0.0 3.5 2 1 2 4 4 4 2 V-ATPase subunit H HEAT_PBS PF03130.11 CDJ68568.1 - 0.011 16.1 9.2 0.089 13.3 0.0 6.2 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Gly-zipper_OmpA PF13436.1 CDJ68568.1 - 0.21 11.2 3.7 0.58 9.8 2.6 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Proteasom_PSMB PF10508.4 CDJ68568.1 - 0.22 9.7 0.0 2.9 6.0 0.0 2.0 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Pkinase PF00069.20 CDJ68569.1 - 5.4e-55 186.3 2.3 5.9e-48 163.2 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68569.1 - 1.7e-17 63.3 5.1 5.9e-15 55.0 0.0 3.1 3 1 1 4 4 4 2 Protein tyrosine kinase EF-hand_7 PF13499.1 CDJ68569.1 - 1.2e-16 60.6 1.4 1e-07 31.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDJ68569.1 - 9.3e-16 55.8 1.1 0.0029 16.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CDJ68569.1 - 3e-12 45.9 0.6 4.5e-05 22.9 0.0 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CDJ68569.1 - 4.6e-12 44.7 1.5 0.00041 20.0 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CDJ68569.1 - 0.0019 17.4 0.3 0.59 9.5 0.0 3.1 3 0 0 3 3 3 1 EF hand YrbL-PhoP_reg PF10707.4 CDJ68569.1 - 0.19 11.0 0.0 0.19 11.0 0.0 2.8 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL PAT1 PF09770.4 CDJ68569.1 - 2.9 6.0 80.9 0.03 12.6 48.8 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 CDJ68570.1 - 4.4e-09 35.9 0.2 0.00051 19.6 0.0 3.4 3 1 0 3 3 3 2 Mitochondrial carrier protein DUF966 PF06136.8 CDJ68570.1 - 0.71 9.2 13.0 0.18 11.1 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) SPX PF03105.14 CDJ68571.1 - 9.9e-07 28.8 8.7 34 4.0 0.0 3.2 2 1 1 3 3 3 1 SPX domain Neur_chan_memb PF02932.11 CDJ68571.1 - 0.041 13.7 16.3 2.8 7.7 8.1 3.4 3 1 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 CDJ68571.1 - 0.2 9.8 61.0 0.0067 14.7 29.2 3.3 3 0 0 3 3 3 0 Transmembrane protein Ribosomal_60s PF00428.14 CDJ68572.1 - 0.028 14.7 3.3 0.028 14.7 2.3 3.9 3 1 0 3 3 3 0 60s Acidic ribosomal protein Med15 PF09606.5 CDJ68573.1 - 1.5e-06 26.7 35.8 0.00069 17.9 7.6 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal PMI_typeI PF01238.16 CDJ68573.1 - 3.8e-05 22.8 0.2 3.8e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 Phosphomannose isomerase type I SPX PF03105.14 CDJ68573.1 - 0.00021 21.1 6.0 0.00032 20.5 4.2 1.2 1 0 0 1 1 1 1 SPX domain Spt20 PF12090.3 CDJ68573.1 - 0.0011 18.3 1.6 0.0011 18.3 1.1 2.3 2 1 0 2 2 1 1 Spt20 family Plasmodium_Vir PF05795.6 CDJ68573.1 - 0.069 12.3 0.0 0.069 12.3 0.0 2.0 1 1 0 2 2 2 0 Plasmodium vivax Vir protein DUF106 PF01956.11 CDJ68573.1 - 0.13 11.7 8.0 0.69 9.4 2.8 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 Suf PF05843.9 CDJ68573.1 - 0.24 11.1 18.0 1.3 8.6 2.7 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SpoVR PF04293.8 CDJ68573.1 - 0.31 9.3 8.6 0.036 12.4 0.9 2.0 2 0 0 2 2 2 0 SpoVR like protein CAF-1_p150 PF11600.3 CDJ68573.1 - 0.93 8.8 23.3 0.25 10.6 9.7 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDJ68573.1 - 1.1 7.4 38.3 0.35 9.0 6.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ68573.1 - 1.7 8.8 22.0 0.14 12.4 2.8 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_U57 PF05582.7 CDJ68573.1 - 2 7.2 7.0 0.81 8.5 1.3 2.0 2 0 0 2 2 2 0 YabG peptidase U57 DUF607 PF04678.8 CDJ68573.1 - 3.5 7.5 6.7 2.7 7.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF607 CDK2AP PF09806.4 CDJ68573.1 - 6.7 6.9 26.6 4.6e+02 0.8 18.5 2.2 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SprA-related PF12118.3 CDJ68573.1 - 6.7 5.9 40.7 0.11 11.8 11.1 2.3 2 0 0 2 2 2 0 SprA-related family EphA2_TM PF14575.1 CDJ68573.1 - 8.3 6.8 8.3 10 6.6 0.5 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MDFI PF15316.1 CDJ68573.1 - 9.7 6.1 11.9 5.4 6.9 0.1 3.0 3 0 0 3 3 3 0 MyoD family inhibitor MCM_N PF14551.1 CDJ68574.1 - 4e-06 27.3 0.0 8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain PAT1 PF09770.4 CDJ68574.1 - 0.021 13.1 10.8 0.024 12.9 7.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDJ68574.1 - 0.029 14.7 15.6 0.17 12.2 5.6 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein PsbQ PF05757.6 CDJ68574.1 - 1.8 7.9 7.2 0.29 10.5 1.0 2.1 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) SHR3_chaperone PF08229.6 CDJ68574.1 - 2.3 7.1 6.0 0.77 8.6 1.2 1.9 2 0 0 2 2 2 0 ER membrane protein SH3 Suf PF05843.9 CDJ68574.1 - 4.4 6.9 5.8 6.6 6.3 4.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ68575.1 - 0.00025 19.4 111.9 0.00025 19.4 77.6 3.7 2 1 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2803 PF10972.3 CDJ68575.1 - 0.00038 20.0 4.7 0.00038 20.0 3.3 5.7 1 1 3 4 4 4 2 Protein of unknown function (DUF2803) PAD_M PF08527.5 CDJ68575.1 - 0.48 9.7 7.4 1.6 8.1 5.1 1.9 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain DUF1517 PF07466.6 CDJ68576.1 - 0.13 11.2 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) ArabFuran-catal PF09206.6 CDJ68577.1 - 0.0029 16.5 0.5 0.0029 16.5 0.3 1.8 1 1 1 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic Hydrophobin_2 PF06766.6 CDJ68577.1 - 0.0074 15.9 1.3 0.0074 15.9 0.9 1.7 1 1 1 2 2 2 1 Fungal hydrophobin eIF3g PF12353.3 CDJ68577.1 - 1.5 8.7 9.2 0.66 9.8 0.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Silic_transp PF03842.8 CDJ68577.1 - 1.8 6.5 5.4 2 6.4 3.7 1.0 1 0 0 1 1 1 0 Silicon transporter Gti1_Pac2 PF09729.4 CDJ68577.1 - 8.4 6.2 13.2 0.09 12.6 1.8 1.9 1 1 1 2 2 2 0 Gti1/Pac2 family Senescence_reg PF04520.8 CDJ68578.1 - 0.11 12.9 0.4 0.19 12.1 0.2 1.4 1 1 0 1 1 1 0 Senescence regulator SIM_C PF06621.7 CDJ68578.1 - 0.24 10.9 7.2 0.3 10.6 5.0 1.1 1 0 0 1 1 1 0 Single-minded protein C-terminus Longin PF13774.1 CDJ68579.1 - 3.6e-17 61.6 0.0 7e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CDJ68579.1 - 5.9e-15 54.6 0.6 1.3e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 Synaptobrevin DUF2284 PF10050.4 CDJ68579.1 - 0.0095 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) HBS1_N PF08938.5 CDJ68579.1 - 0.059 13.4 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 HBS1 N-terminus SR-25 PF10500.4 CDJ68579.1 - 3 7.2 6.5 0.59 9.5 2.2 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HMG_box PF00505.14 CDJ68580.1 - 6.3e-20 71.2 2.8 9.4e-20 70.6 2.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDJ68580.1 - 2.2e-11 43.9 3.0 3.2e-11 43.4 2.1 1.3 1 0 0 1 1 1 1 HMG-box domain Tol_Tol_Ttg2 PF05494.7 CDJ68580.1 - 0.0059 16.1 1.2 0.008 15.7 0.8 1.2 1 0 0 1 1 1 1 Toluene tolerance, Ttg2 CAF-1_p150 PF11600.3 CDJ68580.1 - 0.077 12.3 8.7 0.1 11.9 6.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sporozoite_P67 PF05642.6 CDJ68580.1 - 0.1 10.4 6.0 0.11 10.3 4.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 CDJ68580.1 - 8.2 4.3 10.2 7 4.6 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CIAPIN1 PF05093.8 CDJ68582.1 - 7.9 6.6 11.2 36 4.5 7.8 2.1 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Spore_coat_CotO PF14153.1 CDJ68583.1 - 0.027 13.8 4.4 0.026 13.9 3.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Phostensin_N PF13916.1 CDJ68583.1 - 0.036 14.0 2.8 0.053 13.5 1.9 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Med25_VWA PF11265.3 CDJ68583.1 - 0.043 12.8 0.4 0.043 12.8 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A TMEM154 PF15102.1 CDJ68583.1 - 0.055 13.1 0.4 0.068 12.8 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Suf PF05843.9 CDJ68583.1 - 0.12 12.0 2.2 0.15 11.7 1.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DBR1 PF05011.8 CDJ68583.1 - 0.22 11.4 2.7 0.29 11.0 1.9 1.2 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain TraV PF09676.5 CDJ68583.1 - 0.39 11.4 7.2 0.48 11.1 5.0 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) APC_CDC26 PF10471.4 CDJ68583.1 - 0.41 11.4 6.8 0.21 12.3 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 TFIIA PF03153.8 CDJ68583.1 - 0.42 10.4 8.5 0.44 10.3 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF390 PF04094.9 CDJ68583.1 - 1.6 6.6 16.3 1.7 6.6 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF966 PF06136.8 CDJ68583.1 - 4.2 6.7 7.4 4.8 6.4 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MSP1_C PF07462.6 CDJ68583.1 - 5.6 5.2 11.6 6.8 4.9 8.1 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Med15 PF09606.5 CDJ68583.1 - 7.3 4.6 17.2 9.3 4.3 11.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MFS_1 PF07690.11 CDJ68585.1 - 6.1e-14 51.5 33.5 3.7e-10 39.0 2.0 3.6 3 1 1 4 4 4 2 Major Facilitator Superfamily Spt20 PF12090.3 CDJ68585.1 - 0.05 12.9 2.9 4.2 6.6 0.1 2.3 2 0 0 2 2 2 0 Spt20 family DUF4094 PF13334.1 CDJ68585.1 - 0.062 13.6 5.2 1.7 9.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Conotoxin PF02950.12 CDJ68585.1 - 0.31 11.8 0.0 0.31 11.8 0.0 3.5 4 0 0 4 4 4 0 Conotoxin SNARE_assoc PF09335.6 CDJ68587.1 - 0.048 13.8 0.6 0.24 11.6 0.4 2.2 1 0 0 1 1 1 0 SNARE associated Golgi protein PAN_4 PF14295.1 CDJ68588.1 - 5.4e-32 109.2 18.3 1.8e-10 40.3 0.2 4.6 4 0 0 4 4 4 4 PAN domain Zip PF02535.17 CDJ68588.1 - 0.092 11.7 8.5 0.15 11.0 3.9 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RE_NgoPII PF09521.5 CDJ68588.1 - 0.31 9.7 0.2 0.49 9.1 0.1 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease Tim54 PF11711.3 CDJ68588.1 - 0.67 8.4 3.0 0.71 8.4 1.0 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 ETRAMP PF09716.5 CDJ68588.1 - 0.86 9.6 0.0 0.86 9.6 0.0 4.0 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) TLP-20 PF06088.6 CDJ68588.1 - 3.1 7.4 7.0 3.3 7.3 1.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Raftlin PF15250.1 CDJ68588.1 - 7.8 4.9 12.1 12 4.2 6.1 2.0 2 0 0 2 2 2 0 Raftlin TCP PF03634.8 CDJ68588.1 - 8 6.8 27.0 9.1 6.6 2.8 2.6 2 0 0 2 2 2 0 TCP family transcription factor RRP14 PF15459.1 CDJ68590.1 - 0.26 11.3 8.0 0.44 10.6 5.6 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Conotoxin PF02950.12 CDJ68590.1 - 0.76 10.6 3.1 1.2 9.9 2.1 1.4 1 0 0 1 1 1 0 Conotoxin BRF1 PF07741.8 CDJ68590.1 - 1 9.5 11.2 1.5 9.0 7.7 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FimP PF09766.4 CDJ68590.1 - 1.1 8.3 9.3 1.2 8.1 6.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF2215 PF10225.4 CDJ68590.1 - 1.3 8.4 5.2 1.4 8.3 3.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) NinG PF05766.7 CDJ68590.1 - 1.7 8.3 8.5 2 8.1 5.9 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DDRGK PF09756.4 CDJ68590.1 - 3.7 6.8 12.4 4.2 6.7 8.6 1.1 1 0 0 1 1 1 0 DDRGK domain Baculo_PP31 PF05311.6 CDJ68590.1 - 4.8 6.3 7.4 5.2 6.2 5.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_S49_N PF08496.5 CDJ68590.1 - 5.4 6.8 5.6 6.4 6.5 3.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3043 PF11241.3 CDJ68590.1 - 9.3 5.8 10.8 12 5.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) FAIM1 PF06905.8 CDJ68592.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Spt20 PF12090.3 CDJ68592.1 - 0.19 11.0 3.2 0.22 10.8 0.2 2.3 3 0 0 3 3 3 0 Spt20 family PAT1 PF09770.4 CDJ68592.1 - 3.9 5.5 29.4 0.18 9.9 14.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RCC1 PF00415.13 CDJ68594.1 - 3.9e-08 33.3 0.9 0.00012 22.2 0.0 2.9 2 1 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ68594.1 - 3.3e-05 23.3 1.0 0.00033 20.1 0.2 2.6 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Med15 PF09606.5 CDJ68594.1 - 0.002 16.4 0.3 0.002 16.4 0.2 2.9 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ68594.1 - 0.014 15.1 5.2 0.14 11.8 0.4 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ68594.1 - 0.028 13.7 5.3 0.7 9.2 0.4 2.3 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDJ68594.1 - 3.6 6.5 16.5 3.6 6.5 3.1 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF4557 PF15101.1 CDJ68594.1 - 6.1 6.6 15.1 0.47 10.2 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Ras PF00071.17 CDJ68595.1 - 8.9e-41 138.9 0.1 1.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ68595.1 - 8e-10 39.2 0.0 1.7e-09 38.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CDJ68595.1 - 1.5e-08 34.3 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CDJ68595.1 - 2.7e-08 33.2 0.0 3.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Phage_tail_S PF05069.8 CDJ68595.1 - 0.0086 15.8 1.7 0.016 14.9 1.2 1.4 1 0 0 1 1 1 1 Phage virion morphogenesis family PhaC_N PF07167.8 CDJ68595.1 - 0.022 14.1 0.4 0.029 13.7 0.3 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Gtr1_RagA PF04670.7 CDJ68595.1 - 0.028 13.5 0.0 0.048 12.7 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Med3 PF11593.3 CDJ68595.1 - 0.28 10.3 7.0 0.36 10.0 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.17 CDJ68596.1 - 3.8e-60 199.4 0.0 2.1e-18 65.6 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ68596.1 - 5.4e-40 135.2 0.0 2.3e-11 43.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CDJ68596.1 - 3.1e-29 100.4 1.7 3.1e-29 100.4 1.2 4.6 6 0 0 6 6 6 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 CDJ68596.1 - 3.6e-29 100.3 0.0 1.1e-09 37.9 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Claudin_2 PF13903.1 CDJ68596.1 - 0.018 14.7 0.4 0.018 14.7 0.3 3.1 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Glycolytic PF00274.14 CDJ68597.1 - 5.1e-154 511.8 0.0 7.6e-154 511.2 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I NUDIX-like PF09296.6 CDJ68597.1 - 1.1 9.6 4.4 1.7 9.0 0.2 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase-like rudimentary NUDIX domain DUF179 PF02622.10 CDJ68598.1 - 3.9e-07 29.8 0.1 0.00096 18.8 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized ACR, COG1678 RRM_6 PF14259.1 CDJ68599.1 - 0.00073 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ68599.1 - 0.00091 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2681 PF10883.3 CDJ68599.1 - 1.3 9.3 16.0 0.25 11.5 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) CENP-H PF05837.7 CDJ68599.1 - 3 8.0 11.2 2.5 8.3 3.1 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.10 CDJ68599.1 - 3.9 7.0 16.3 0.61 9.6 1.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Spt20 PF12090.3 CDJ68599.1 - 9.3 5.5 7.2 3.4 6.9 0.8 2.0 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.4 CDJ68600.1 - 0.0027 17.2 13.4 0.0027 17.2 9.3 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CytochromB561_N PF09786.4 CDJ68600.1 - 9 4.6 7.2 17 3.7 5.0 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF737 PF05300.6 CDJ68601.1 - 0.00094 19.1 0.1 0.00094 19.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF737) TMEM171 PF15471.1 CDJ68601.1 - 0.057 12.1 1.9 0.093 11.5 1.3 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Sporozoite_P67 PF05642.6 CDJ68601.1 - 0.25 9.1 2.3 0.33 8.7 1.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apc15p PF05841.6 CDJ68601.1 - 0.3 11.8 8.9 0.21 12.3 3.7 2.1 2 0 0 2 2 2 0 Apc15p protein Suf PF05843.9 CDJ68601.1 - 0.45 10.1 4.1 0.62 9.7 2.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3043 PF11241.3 CDJ68601.1 - 0.97 9.0 3.5 1.8 8.1 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Rabaptin PF03528.10 CDJ68602.1 - 9 6.2 8.3 3.3 7.6 3.5 1.9 2 0 0 2 2 2 0 Rabaptin Topoisom_bac PF01131.15 CDJ68603.1 - 1.5e-93 313.8 0.0 1.8e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase DUF187 PF02638.10 CDJ68603.1 - 0.17 10.7 0.1 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 GTP_EFTU PF00009.22 CDJ68605.1 - 1.3e-28 99.7 0.0 1.3e-27 96.4 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CDJ68605.1 - 4.2e-22 77.8 0.0 9.9e-22 76.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CDJ68605.1 - 2e-21 75.7 0.0 5.2e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 CDJ68605.1 - 0.00066 19.7 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CDJ68605.1 - 0.15 12.5 0.0 0.65 10.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Aminotran_3 PF00202.16 CDJ68606.1 - 5.5e-113 377.2 0.0 6.5e-113 377.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CDJ68606.1 - 0.0072 15.3 0.0 0.015 14.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II MHC_I PF00129.13 CDJ68606.1 - 0.09 12.1 0.0 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 DnaJ PF00226.26 CDJ68607.1 - 2.5e-10 39.9 0.5 6.8e-10 38.5 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain TraG_N PF07916.6 CDJ68607.1 - 0.048 12.1 0.0 0.079 11.3 0.0 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region KH_1 PF00013.24 CDJ68608.1 - 4.5e-35 119.0 0.1 1.7e-09 37.1 0.1 4.7 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 CDJ68608.1 - 2.4e-28 97.2 1.6 6.1e-07 28.9 0.1 4.8 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 CDJ68608.1 - 0.001 18.6 0.0 0.44 10.1 0.0 3.2 3 0 0 3 3 3 1 KH domain Pkinase PF00069.20 CDJ68609.1 - 1.5e-27 96.4 0.0 2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDJ68609.1 - 1.8e-22 79.6 0.0 2.5e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDJ68609.1 - 8e-06 25.0 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CDJ68609.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 CDJ68610.1 - 1.2e-16 60.4 48.4 5.9e-13 48.2 21.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDJ68610.1 - 3.3 6.0 21.2 0.26 9.6 2.1 3.1 3 0 0 3 3 3 0 MFS/sugar transport protein Beta-lactamase PF00144.19 CDJ68611.1 - 2.1e-39 135.5 0.0 2.5e-35 122.0 0.0 3.2 3 0 0 3 3 3 2 Beta-lactamase ABC1 PF03109.11 CDJ68611.1 - 1.3e-23 83.2 0.0 2.6e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 CDJ68611.1 - 0.00028 20.1 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RabGAP-TBC PF00566.13 CDJ68612.1 - 1.1e-33 116.5 1.7 7e-32 110.6 0.1 2.6 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Kinase-like PF14531.1 CDJ68613.1 - 9e-21 74.0 0.0 1.3e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Mito_carr PF00153.22 CDJ68614.1 - 4.6e-35 119.1 4.9 9.5e-13 47.6 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein FAD_binding_7 PF03441.9 CDJ68615.1 - 3.5e-30 105.1 0.3 4.7e-29 101.4 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CDJ68615.1 - 5.5e-16 58.7 0.1 1.2e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 DNA photolyase CMS1 PF14617.1 CDJ68615.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DIM1 PF02966.11 CDJ68616.1 - 5.7e-63 210.3 1.3 6.8e-63 210.1 0.9 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CDJ68616.1 - 0.006 16.2 0.1 0.008 15.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin DUF2387 PF09526.5 CDJ68616.1 - 0.045 13.6 1.0 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Orbi_VP3 PF01700.11 CDJ68616.1 - 0.048 11.1 0.0 0.054 10.9 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Adap_comp_sub PF00928.16 CDJ68617.1 - 1.2e-81 273.7 0.0 1.4e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CDJ68617.1 - 2.5e-05 24.0 0.2 4.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Rep_fac_C PF08542.6 CDJ68617.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain Adaptin_N PF01602.15 CDJ68618.1 - 2.7e-95 319.6 1.0 2.1e-94 316.7 0.7 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CDJ68618.1 - 8.5e-15 55.0 0.0 2.6e-14 53.5 0.0 1.8 1 1 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CDJ68618.1 - 3.3e-05 24.0 17.7 0.011 16.0 0.6 5.1 4 3 1 5 5 5 3 HEAT repeats Cnd1 PF12717.2 CDJ68618.1 - 0.0046 16.8 3.6 0.014 15.2 0.3 3.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CDJ68618.1 - 0.15 12.1 5.4 0.88 9.8 0.2 4.7 5 1 0 5 5 5 0 HEAT repeat zf-C2HC_2 PF13913.1 CDJ68619.1 - 4.3e-09 35.8 13.6 2.6e-05 23.7 0.1 4.6 4 0 0 4 4 4 3 zinc-finger of a C2HC-type PyrI_C PF02748.10 CDJ68619.1 - 0.019 14.4 0.1 4.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain ADK_lid PF05191.9 CDJ68619.1 - 0.089 12.4 3.8 13 5.5 0.1 3.7 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C2H2_6 PF13912.1 CDJ68619.1 - 4.5 7.3 6.7 6.3 6.8 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Sgf11 PF08209.6 CDJ68619.1 - 7.1 6.0 13.7 4 6.8 0.7 3.5 3 1 0 3 3 3 0 Sgf11 (transcriptional regulation protein) HypA PF01155.14 CDJ68619.1 - 7.2 6.3 7.6 3.9 7.2 0.6 2.8 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family SNF2_N PF00176.18 CDJ68621.1 - 8.3e-65 218.5 0.0 8.3e-65 218.5 0.0 3.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDJ68621.1 - 8.4e-16 57.6 0.7 7.5e-15 54.5 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CDJ68621.1 - 1.2e-10 40.7 0.0 3.8e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Asp-B-Hydro_N PF05279.6 CDJ68621.1 - 2.4 7.9 13.8 0.87 9.3 6.7 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region eIF-3c_N PF05470.7 CDJ68623.1 - 2e-136 455.5 18.9 7.1e-101 338.1 1.4 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CDJ68623.1 - 1.3e-13 51.2 0.5 5.2e-13 49.2 0.1 2.4 2 0 0 2 2 2 1 PCI domain Daxx PF03344.10 CDJ68623.1 - 0.21 10.0 25.8 0.42 9.0 17.9 1.4 1 0 0 1 1 1 0 Daxx Family Med15 PF09606.5 CDJ68624.1 - 2.6 6.1 100.5 3.8 5.5 69.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAP1 PF07218.6 CDJ68624.1 - 3.9 5.4 10.8 5.1 5.0 7.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.14 CDJ68625.1 - 0.016 15.6 11.3 0.016 15.6 7.8 9.9 7 2 1 8 8 8 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDJ68626.1 - 3.2e-05 23.4 18.6 3.2e-05 23.4 12.9 3.8 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein CRT10 PF08728.5 CDJ68626.1 - 2.1 6.2 19.1 0.36 8.7 7.9 2.1 2 0 0 2 2 2 0 CRT10 Glycos_transf_2 PF00535.21 CDJ68627.1 - 4.6e-07 29.6 0.0 8.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 SR-25 PF10500.4 CDJ68627.1 - 2 7.8 9.8 3.8 6.9 6.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_ligase_A_M PF01068.16 CDJ68628.1 - 7.6e-34 116.8 0.1 4.2e-32 111.1 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 CDJ68628.1 - 2e-06 28.1 0.7 4.9e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Spt20 PF12090.3 CDJ68628.1 - 0.089 12.1 3.2 0.068 12.5 0.6 1.9 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.8 CDJ68628.1 - 7.7 6.3 37.8 0.68 9.7 7.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tetraspannin PF00335.15 CDJ68629.1 - 1.5 8.0 10.7 3.4 6.8 7.4 1.6 1 0 0 1 1 1 0 Tetraspanin family Spt20 PF12090.3 CDJ68629.1 - 6.6 6.0 7.6 3.5 6.9 0.9 2.2 2 0 0 2 2 2 0 Spt20 family CDK5_activator PF03261.10 CDJ68631.1 - 0.3 10.3 18.0 0.12 11.7 4.3 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Peptidase_S49_N PF08496.5 CDJ68631.1 - 7 6.4 12.0 2.3 7.9 3.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PepSY_2 PF13670.1 CDJ68632.1 - 6.9 6.6 9.0 25 4.8 6.3 2.0 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain AAA PF00004.24 CDJ68633.1 - 1.3e-10 41.5 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ribosomal_60s PF00428.14 CDJ68633.1 - 0.0087 16.4 7.1 0.0087 16.4 4.9 2.9 3 0 0 3 3 3 1 60s Acidic ribosomal protein Calici_coat PF00915.15 CDJ68633.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein IncA PF04156.9 CDJ68634.1 - 6.7e-05 22.5 19.7 6.7e-05 22.5 13.7 1.9 2 0 0 2 2 2 1 IncA protein AAA_23 PF13476.1 CDJ68634.1 - 0.027 14.7 16.3 0.036 14.3 11.3 1.3 1 0 0 1 1 1 0 AAA domain FPN1 PF06963.7 CDJ68634.1 - 0.065 11.6 6.3 0.073 11.4 4.4 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Choline_transpo PF04515.7 CDJ68634.1 - 0.072 11.8 0.1 0.091 11.4 0.1 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter CAF-1_p150 PF11600.3 CDJ68634.1 - 0.3 10.4 24.5 0.36 10.1 17.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDJ68634.1 - 0.7 9.3 19.3 0.92 8.9 13.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VIT1 PF01988.14 CDJ68634.1 - 0.76 9.2 15.6 1 8.8 10.5 1.4 1 1 0 1 1 1 0 VIT family Adaptin_binding PF10199.4 CDJ68634.1 - 1.2 9.4 21.2 1.6 8.9 14.7 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 TraT PF05818.7 CDJ68634.1 - 1.2 8.4 20.8 1.7 8.0 14.4 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein CDC45 PF02724.9 CDJ68634.1 - 1.3 7.0 14.8 1.5 6.8 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 CDJ68634.1 - 1.3 7.7 22.1 1.6 7.4 15.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Apt1 PF10351.4 CDJ68634.1 - 1.7 7.3 12.0 2 7.1 8.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ycf1 PF05758.7 CDJ68634.1 - 1.9 6.1 16.2 1.6 6.3 11.2 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDJ68634.1 - 1.9 6.0 18.0 2.3 5.8 12.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDJ68634.1 - 3 6.2 19.8 3.7 5.9 13.7 1.1 1 0 0 1 1 1 0 Raftlin Anoctamin PF04547.7 CDJ68634.1 - 3.6 6.1 8.0 3.3 6.2 5.6 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel BTV_NS2 PF04514.7 CDJ68634.1 - 3.7 6.3 13.8 4.2 6.1 9.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SID-1_RNA_chan PF13965.1 CDJ68634.1 - 4.2 5.4 8.8 4 5.4 6.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CD20 PF04103.10 CDJ68634.1 - 4.2 7.2 10.3 6.1 6.7 6.8 1.7 1 1 0 1 1 1 0 CD20-like family Peptidase_U57 PF05582.7 CDJ68634.1 - 5 5.9 15.2 7.3 5.4 10.5 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Hamartin PF04388.7 CDJ68634.1 - 8 4.9 22.5 9 4.8 15.6 1.0 1 0 0 1 1 1 0 Hamartin protein Herpes_glycop PF01528.11 CDJ68634.1 - 9.3 4.8 8.4 12 4.4 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Exonuc_VII_L PF02601.10 CDJ68634.1 - 9.5 5.3 23.4 16 4.5 16.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ribosomal_60s PF00428.14 CDJ68635.1 - 0.0055 17.0 11.3 0.0055 17.0 7.8 13.1 11 2 1 12 12 12 6 60s Acidic ribosomal protein EMG1 PF03587.9 CDJ68637.1 - 2.2e-17 63.0 0.9 3e-13 49.5 0.4 3.6 2 2 0 2 2 2 2 EMG1/NEP1 methyltransferase Syntaxin PF00804.20 CDJ68638.1 - 0.047 13.8 2.1 2.9 8.1 2.0 2.3 2 0 0 2 2 2 0 Syntaxin DUF4446 PF14584.1 CDJ68639.1 - 0.73 9.6 4.9 1.1 9.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PSP PF04046.11 CDJ68640.1 - 8.6e-21 73.0 8.5 1.6e-20 72.2 5.9 1.5 1 0 0 1 1 1 1 PSP zf-HIT PF04438.11 CDJ68642.1 - 2.8e-08 33.2 13.2 5.2e-08 32.3 9.2 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF4175 PF13779.1 CDJ68642.1 - 0.53 7.9 67.8 0.08 10.6 19.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) BTV_NS2 PF04514.7 CDJ68642.1 - 0.57 9.0 15.0 0.94 8.2 2.7 2.3 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Utp11 PF03998.8 CDJ68642.1 - 6.7 6.4 32.3 7.7 6.2 8.1 2.3 2 0 0 2 2 2 0 Utp11 protein PAT1 PF09770.4 CDJ68642.1 - 9.4 4.3 50.6 3.2 5.8 14.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Rad60-SLD_2 PF13881.1 CDJ68643.1 - 7e-08 32.3 0.1 7e-08 32.3 0.1 4.7 4 2 1 5 5 5 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 CDJ68643.1 - 0.00038 20.0 0.0 0.00038 20.0 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 CDJ68643.1 - 0.0036 17.8 0.2 0.019 15.5 0.1 2.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PepSY_TM_2 PF13703.1 CDJ68644.1 - 0.043 13.9 2.9 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 PepSY-associated TM helix MRAP PF15183.1 CDJ68644.1 - 0.26 10.9 2.4 7.2 6.2 0.2 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Fig1 PF12351.3 CDJ68644.1 - 1.7 8.4 6.2 1.6 8.5 0.8 2.1 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 ODV-E18 PF10717.4 CDJ68644.1 - 3.7 7.0 6.2 0.24 10.8 0.2 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Adaptin_N PF01602.15 CDJ68645.1 - 1.7e-28 99.2 0.1 8.7e-25 87.0 0.2 2.4 2 1 0 2 2 2 2 Adaptin N terminal region PSCyt3 PF07627.6 CDJ68645.1 - 0.65 9.8 5.2 3.3 7.6 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) LSM PF01423.17 CDJ68647.1 - 1.4e-15 56.6 0.8 1.7e-15 56.3 0.6 1.1 1 0 0 1 1 1 1 LSM domain AAA_25 PF13481.1 CDJ68649.1 - 3.6e-07 29.7 0.0 3.1e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad51 PF08423.6 CDJ68649.1 - 5.7e-06 25.4 0.1 0.0021 17.0 0.0 3.1 2 1 0 2 2 2 1 Rad51 RecA PF00154.16 CDJ68649.1 - 0.0092 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CDJ68649.1 - 0.029 13.4 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 KaiC XPG_I PF00867.13 CDJ68650.1 - 2.9e-14 52.8 0.1 6.9e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CDJ68650.1 - 8.7e-11 41.9 0.0 7e-05 23.0 0.0 2.7 3 0 0 3 3 3 2 XPG N-terminal domain AP2 PF00847.15 CDJ68651.1 - 2.4e-11 43.6 0.6 2.4e-11 43.6 0.4 5.0 5 1 1 6 6 6 1 AP2 domain SR-25 PF10500.4 CDJ68651.1 - 0.18 11.2 37.2 0.017 14.6 4.4 4.0 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein FlxA PF14282.1 CDJ68652.1 - 0.033 14.1 0.1 0.033 14.1 0.1 5.5 5 0 0 5 5 5 0 FlxA-like protein Collagen PF01391.13 CDJ68653.1 - 2e-05 24.0 10.8 3.6e-05 23.2 7.5 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) RAB3GAP2_N PF14655.1 CDJ68653.1 - 0.26 10.2 8.3 1.1 8.1 1.6 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus LYTB PF02401.13 CDJ68654.1 - 1.6e-76 256.8 2.9 2e-61 207.3 0.5 2.2 2 0 0 2 2 2 2 LytB protein SR-25 PF10500.4 CDJ68654.1 - 4.8 6.5 17.8 0.7 9.3 9.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FHA PF00498.21 CDJ68656.1 - 5.8e-16 58.3 0.1 9e-08 32.1 0.1 2.5 2 0 0 2 2 2 2 FHA domain Collagen PF01391.13 CDJ68656.1 - 1.4e-05 24.5 15.5 1.4e-05 24.5 10.7 6.7 3 2 1 4 4 4 2 Collagen triple helix repeat (20 copies) DUF515 PF04415.7 CDJ68656.1 - 1.1 7.4 2.8 3.8 5.6 1.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.4 CDJ68657.1 - 0.067 12.6 5.7 0.14 11.6 3.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.17 CDJ68658.1 - 5.3e-24 83.6 0.0 1.4e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ68658.1 - 4.3e-19 68.2 0.0 6.1e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ68658.1 - 8.6e-06 25.5 0.0 0.007 16.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) D123 PF07065.9 CDJ68659.1 - 2.5e-14 53.0 0.0 3.2e-10 39.5 0.0 3.1 3 0 0 3 3 3 2 D123 Nuc_sug_transp PF04142.10 CDJ68660.1 - 0.0025 16.9 4.2 0.017 14.2 1.5 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 CDJ68660.1 - 0.36 10.8 35.6 0.021 14.8 7.2 3.3 4 0 0 4 4 4 0 EamA-like transporter family His_Phos_2 PF00328.17 CDJ68662.1 - 1e-39 136.8 23.6 1.4e-37 129.8 1.6 4.2 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) Frizzled PF01534.12 CDJ68662.1 - 0.55 8.9 0.2 0.9 8.2 0.1 1.3 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region HEAT PF02985.17 CDJ68663.1 - 1.2e-14 52.9 9.6 0.0031 17.4 0.1 5.5 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 CDJ68663.1 - 9.3e-08 32.2 4.0 4.4e-06 26.8 0.4 6.0 6 0 0 6 6 6 2 HEAT repeats Pkinase PF00069.20 CDJ68663.1 - 1.2e-06 27.8 0.0 2.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CDJ68663.1 - 0.0025 17.6 2.9 0.0075 16.1 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat ACDC PF14733.1 CDJ68665.1 - 3e-08 33.6 0.1 0.00096 19.2 0.0 3.1 3 0 0 3 3 3 2 AP2-coincident C-terminal MerR-DNA-bind PF09278.6 CDJ68666.1 - 0.02 15.2 10.4 0.72 10.2 0.5 2.7 2 0 0 2 2 2 0 MerR, DNA binding Death PF00531.17 CDJ68666.1 - 2.6 7.8 11.3 5.7 6.7 1.4 2.3 2 0 0 2 2 2 0 Death domain Syntaxin-6_N PF09177.6 CDJ68666.1 - 3.6 8.0 8.6 10 6.6 0.7 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CLPTM1 PF05602.7 CDJ68667.1 - 4.1e-25 88.3 0.0 9.6e-25 87.1 0.0 1.5 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) AATF-Che1 PF13339.1 CDJ68668.1 - 0.0072 16.4 0.7 0.014 15.5 0.5 1.5 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor Striatin PF08232.7 CDJ68668.1 - 0.016 15.5 2.0 3 8.1 0.8 2.3 2 0 0 2 2 2 0 Striatin family ADIP PF11559.3 CDJ68668.1 - 0.074 12.9 1.5 0.17 11.7 1.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3402 PF11882.3 CDJ68668.1 - 0.081 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) HALZ PF02183.13 CDJ68668.1 - 0.097 12.4 0.3 0.097 12.4 0.2 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper AAA_23 PF13476.1 CDJ68671.1 - 9.5 6.4 16.3 11 6.3 0.1 4.0 3 1 0 3 3 3 0 AAA domain Pkinase PF00069.20 CDJ68674.1 - 2.2e-17 63.0 0.0 2.2e-17 63.0 0.0 4.2 2 2 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68674.1 - 8.8e-10 38.0 0.0 3.1e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase LMWPc PF01451.16 CDJ68676.1 - 1.1e-23 84.0 0.0 1.6e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF615 PF04751.9 CDJ68676.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) tRNA-synt_2d PF01409.15 CDJ68677.1 - 2.7e-29 102.0 0.0 7.9e-22 77.6 0.0 2.5 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) Med15 PF09606.5 CDJ68677.1 - 0.098 10.8 27.0 0.13 10.4 18.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ68677.1 - 0.18 12.2 9.0 0.4 11.1 6.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein TFIIA PF03153.8 CDJ68677.1 - 2.1 8.1 17.9 3 7.6 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.14 CDJ68678.1 - 1.5 9.2 7.6 0.4 11.0 3.2 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF572 PF04502.8 CDJ68678.1 - 3.2 6.8 20.0 3.9 6.6 13.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) HD-ZIP_N PF04618.7 CDJ68678.1 - 4 8.0 13.5 0.32 11.5 2.0 2.1 2 0 0 2 2 2 0 HD-ZIP protein N terminus Ribosomal_60s PF00428.14 CDJ68679.1 - 5.9e-05 23.3 8.5 5.9e-05 23.3 5.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Period_C PF12114.3 CDJ68679.1 - 0.38 10.3 8.3 0.75 9.3 5.8 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Cnd1_N PF12922.2 CDJ68679.1 - 0.52 9.9 5.2 0.77 9.3 0.6 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF3138 PF11336.3 CDJ68679.1 - 1.1 7.3 6.2 1.4 7.0 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) SR-25 PF10500.4 CDJ68679.1 - 1.2 8.5 13.2 2.3 7.6 9.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC_tran PF00005.22 CDJ68684.1 - 1.3e-28 99.9 0.0 3.1e-27 95.5 0.0 3.0 2 1 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 CDJ68684.1 - 1.1e-16 61.0 0.0 1.7e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CDJ68684.1 - 7.5e-07 29.3 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain OmpH PF03938.9 CDJ68684.1 - 0.00023 21.1 4.7 0.00023 21.1 3.3 3.2 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) DUF258 PF03193.11 CDJ68684.1 - 0.0018 17.5 0.1 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CDJ68684.1 - 0.0024 18.6 0.0 0.0053 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CDJ68684.1 - 0.0031 16.3 0.1 0.0084 14.9 0.0 1.6 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 CDJ68684.1 - 0.0048 16.3 0.5 0.076 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CDJ68684.1 - 0.005 17.1 0.1 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CDJ68684.1 - 0.0051 15.5 0.0 0.0079 14.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 CDJ68684.1 - 0.0067 15.9 0.0 0.02 14.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 CDJ68684.1 - 0.0096 16.1 0.8 2 8.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Neur_chan_memb PF02932.11 CDJ68684.1 - 0.016 15.1 3.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region AAA_10 PF12846.2 CDJ68684.1 - 0.017 14.5 0.4 0.049 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain KAP_NTPase PF07693.9 CDJ68684.1 - 0.019 13.9 0.0 0.24 10.3 0.0 2.4 2 1 1 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 CDJ68684.1 - 0.038 12.8 0.6 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Spt20 PF12090.3 CDJ68684.1 - 0.052 12.9 6.0 3.8 6.8 2.2 2.4 2 0 0 2 2 2 0 Spt20 family MobB PF03205.9 CDJ68684.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CDJ68684.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CDJ68684.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 CDJ68684.1 - 0.094 12.5 0.0 0.094 12.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.1 CDJ68684.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF1625 PF07787.7 CDJ68684.1 - 0.21 10.7 0.1 0.21 10.7 0.0 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1625) DUF87 PF01935.12 CDJ68684.1 - 0.22 11.2 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 CDJ68684.1 - 0.53 10.5 15.9 0.57 10.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain tRNA_synt_1c_R2 PF04557.10 CDJ68684.1 - 0.91 10.2 6.1 5.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 OATP PF03137.15 CDJ68684.1 - 1.1 7.2 10.0 0.53 8.2 0.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Suf PF05843.9 CDJ68684.1 - 2.1 8.0 14.2 2.9 7.5 5.5 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ68684.1 - 2.4 6.2 27.2 3.2 5.8 1.7 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BRF1 PF07741.8 CDJ68684.1 - 4 7.7 10.7 0.93 9.7 1.5 3.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain AUX_IAA PF02309.11 CDJ68684.1 - 7.1 6.3 9.0 0.76 9.4 0.7 2.2 2 0 0 2 2 2 0 AUX/IAA family DDHD PF02862.12 CDJ68684.1 - 8.5 6.0 9.3 22 4.7 0.3 2.4 2 0 0 2 2 2 0 DDHD domain DUF572 PF04502.8 CDJ68684.1 - 8.6 5.4 15.9 0.4 9.8 1.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) RIC3 PF15361.1 CDJ68685.1 - 0.98 9.6 5.3 0.51 10.5 1.3 2.0 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4448 PF14610.1 CDJ68687.1 - 0.019 14.4 0.4 0.039 13.4 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Bac_luciferase PF00296.15 CDJ68687.1 - 0.076 12.1 1.0 0.098 11.7 0.7 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Med15 PF09606.5 CDJ68687.1 - 0.2 9.8 42.2 0.23 9.6 29.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal 7tm_1 PF00001.16 CDJ68687.1 - 0.34 10.0 2.9 0.57 9.2 2.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RskA PF10099.4 CDJ68687.1 - 0.39 10.4 8.3 0.54 9.9 5.7 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA X PF00739.14 CDJ68687.1 - 0.4 10.5 4.6 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 Trans-activation protein X Trp_oprn_chp PF09534.5 CDJ68687.1 - 0.46 10.0 4.1 0.52 9.8 2.9 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HCO3_cotransp PF00955.16 CDJ68687.1 - 5.5 5.5 5.5 0.94 8.0 1.5 1.4 1 1 1 2 2 2 0 HCO3- transporter family Lin-8 PF03353.10 CDJ68687.1 - 6.5 5.9 19.4 8.2 5.6 13.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.4 CDJ68687.1 - 6.7 6.1 33.1 28 4.0 23.0 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1360 PF07098.6 CDJ68687.1 - 6.7 6.4 6.2 1.3 8.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1360) DUF2413 PF10310.4 CDJ68687.1 - 8.8 5.0 23.9 10 4.8 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TFIIA PF03153.8 CDJ68687.1 - 9.1 6.0 29.6 11 5.7 20.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIB PF00382.14 CDJ68688.1 - 6.2e-11 41.9 0.1 2.3e-10 40.1 0.1 2.1 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Got1 PF04178.7 CDJ68689.1 - 5.7 7.0 11.6 8.2 6.5 8.0 1.3 1 1 0 1 1 1 0 Got1/Sft2-like family DUF1183 PF06682.7 CDJ68691.1 - 0.77 9.3 18.9 0.082 12.4 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) GPCR_chapero_1 PF11904.3 CDJ68691.1 - 2 7.4 19.6 0.16 11.0 6.5 2.1 2 0 0 2 2 2 0 GPCR-chaperone CRT10 PF08728.5 CDJ68691.1 - 3.4 5.5 9.2 4.3 5.2 6.3 1.1 1 0 0 1 1 1 0 CRT10 NAD_binding_2 PF03446.10 CDJ68692.1 - 2.4e-14 53.4 0.2 2.9e-14 53.2 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 CDJ68692.1 - 0.00012 21.7 0.1 0.00013 21.7 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CDJ68692.1 - 0.037 14.4 0.1 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RAP PF08373.5 CDJ68693.1 - 7.8e-06 25.5 0.1 0.013 15.2 0.0 2.9 2 0 0 2 2 2 2 RAP domain Macoilin PF09726.4 CDJ68693.1 - 0.00011 20.6 14.3 0.00011 20.6 9.9 3.6 2 1 1 3 3 3 1 Transmembrane protein DUF605 PF04652.11 CDJ68693.1 - 0.0013 18.2 31.1 0.0013 18.2 21.5 4.6 4 0 0 4 4 4 4 Vta1 like AMMECR1 PF01871.12 CDJ68695.1 - 3.1e-29 101.3 0.5 1.5e-28 99.0 0.0 2.4 2 0 0 2 2 2 1 AMMECR1 CTD_bind PF04818.8 CDJ68696.1 - 0.0068 16.6 0.1 0.071 13.3 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase II-binding domain. Scs3p PF10261.4 CDJ68697.1 - 1.9e-09 36.9 0.0 1.9e-09 36.9 0.0 3.9 4 0 0 4 4 4 1 Inositol phospholipid synthesis and fat-storage-inducing TM BRF1 PF07741.8 CDJ68699.1 - 0.0094 16.1 8.2 0.79 9.9 2.3 2.4 2 0 0 2 2 2 2 Brf1-like TBP-binding domain RAB3GAP2_N PF14655.1 CDJ68699.1 - 0.032 13.2 10.6 0.73 8.7 0.3 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDJ68699.1 - 0.033 12.4 52.2 0.042 12.0 36.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDJ68699.1 - 0.07 10.8 9.2 0.15 9.7 0.1 2.0 2 0 0 2 2 2 0 Ycf1 SusE PF14292.1 CDJ68699.1 - 0.15 11.9 2.8 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 SusE outer membrane protein Ctr PF04145.10 CDJ68699.1 - 0.37 10.8 4.7 7.5 6.5 0.7 2.2 2 0 0 2 2 2 0 Ctr copper transporter family DUF3371 PF11851.3 CDJ68699.1 - 0.44 11.2 23.1 1.8 9.2 3.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF4557 PF15101.1 CDJ68699.1 - 0.63 9.8 26.5 0.49 10.1 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Peptidase_S49_N PF08496.5 CDJ68699.1 - 0.78 9.5 12.8 2.9 7.6 3.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Suf PF05843.9 CDJ68699.1 - 0.78 9.4 18.7 0.22 11.2 1.5 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.14 CDJ68699.1 - 0.9 9.9 15.4 0.1 13.0 4.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Neur_chan_memb PF02932.11 CDJ68699.1 - 1 9.2 5.9 1.8 8.3 4.1 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 CDJ68699.1 - 1.1 7.4 36.8 0.35 9.0 7.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4414 PF14377.1 CDJ68699.1 - 1.1 9.1 23.4 1.4 8.8 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) DUF3408 PF11888.3 CDJ68699.1 - 1.6 8.6 10.7 6.1 6.7 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF1840 PF08895.6 CDJ68699.1 - 1.8 8.6 18.1 0.6 10.1 1.5 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF1840) DUF2052 PF09747.4 CDJ68699.1 - 2 8.3 19.8 2.2 8.1 2.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Folliculin PF11704.3 CDJ68699.1 - 2.7 7.5 9.7 3.4 7.2 0.4 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport IncA PF04156.9 CDJ68699.1 - 2.7 7.5 30.8 0.034 13.7 3.2 2.4 2 0 0 2 2 2 0 IncA protein DUF2126 PF09899.4 CDJ68699.1 - 4.1 5.3 12.1 2.2 6.1 3.5 2.1 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Spore_coat_CotO PF14153.1 CDJ68699.1 - 4.1 6.7 21.7 2.8 7.3 3.2 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DUF1764 PF08576.5 CDJ68699.1 - 4.3 8.1 15.2 8.3 7.2 3.3 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Peptidase_S15 PF02129.13 CDJ68699.1 - 4.5 6.6 13.7 3.4 6.9 0.4 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2077 PF09850.4 CDJ68699.1 - 4.5 6.6 18.5 3.6 6.9 3.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) SeqA PF03925.8 CDJ68699.1 - 5.1 6.7 15.1 4.1 7.0 3.9 2.1 2 0 0 2 2 2 0 SeqA protein Hom_end_hint PF05203.11 CDJ68699.1 - 5.9 6.5 7.8 9.5 5.8 1.6 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint LIM_bind PF01803.11 CDJ68699.1 - 9.2 5.2 18.5 4.3 6.3 3.5 2.1 2 0 0 2 2 2 0 LIM-domain binding protein Med7 PF05983.6 CDJ68700.1 - 1e-13 51.3 0.0 1e-13 51.3 0.0 2.1 1 1 1 2 2 1 1 MED7 protein CobT PF06213.7 CDJ68700.1 - 0.0096 15.0 3.4 0.0096 15.0 2.4 2.0 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT DUF1183 PF06682.7 CDJ68700.1 - 0.14 11.7 12.1 0.62 9.6 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Band_3_cyto PF07565.8 CDJ68700.1 - 0.19 11.2 16.7 0.36 10.3 8.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Suf PF05843.9 CDJ68700.1 - 0.28 10.8 26.9 1 9.0 1.8 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TCP PF03634.8 CDJ68700.1 - 0.66 10.3 18.2 2 8.8 0.7 2.3 2 0 0 2 2 2 0 TCP family transcription factor AUX_IAA PF02309.11 CDJ68700.1 - 0.66 9.6 11.1 0.99 9.1 4.1 2.1 2 0 0 2 2 2 0 AUX/IAA family DUF2052 PF09747.4 CDJ68700.1 - 0.9 9.4 17.4 1.1 9.0 7.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FLO_LFY PF01698.11 CDJ68700.1 - 1.7 7.3 13.5 0.07 11.9 4.1 1.9 2 0 0 2 2 2 0 Floricaula / Leafy protein Ndc1_Nup PF09531.5 CDJ68700.1 - 2.1 6.6 0.0 2.1 6.6 0.0 2.0 1 1 1 2 2 1 0 Nucleoporin protein Ndc1-Nup Nop25 PF09805.4 CDJ68700.1 - 2.5 8.1 21.5 0.81 9.7 11.1 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Tn7_Tnp_TnsA_C PF08721.6 CDJ68700.1 - 3.3 7.7 6.4 16 5.5 4.4 2.2 1 1 0 1 1 1 0 TnsA endonuclease C terminal DUF3449 PF11931.3 CDJ68700.1 - 3.8 6.9 15.6 0.64 9.4 6.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF3474 PF11960.3 CDJ68700.1 - 4.6 7.2 11.4 0.25 11.3 2.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3474) Neur_chan_memb PF02932.11 CDJ68700.1 - 7 6.4 11.9 15 5.3 6.1 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FUSC PF04632.7 CDJ68700.1 - 9.7 4.4 20.0 17 3.6 13.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3446 PF11928.3 CDJ68701.1 - 0.076 13.2 1.6 0.12 12.5 1.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) CYSTM PF12734.2 CDJ68701.1 - 0.77 9.8 5.4 1.2 9.2 3.8 1.3 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Cyclin PF08613.6 CDJ68702.1 - 1.8e-18 67.4 0.1 1.4e-16 61.2 0.0 3.4 3 0 0 3 3 3 1 Cyclin SAPS PF04499.10 CDJ68702.1 - 2.3 6.7 15.7 0.1 11.2 3.8 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Arm PF00514.18 CDJ68705.1 - 6.8e-08 32.0 41.6 0.00013 21.6 0.5 8.8 9 1 1 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDJ68705.1 - 0.093 13.0 17.8 0.57 10.5 0.2 5.5 4 2 1 5 5 5 0 HEAT repeats Reoviridae_Vp9 PF08978.5 CDJ68705.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Reoviridae VP9 NOC3p PF07540.6 CDJ68706.1 - 1.7e-05 24.9 4.3 0.00026 21.1 0.2 3.7 2 1 1 3 3 3 1 Nucleolar complex-associated protein zf-met2 PF12907.2 CDJ68707.1 - 4e-19 68.2 1.7 6.3e-19 67.6 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 CDJ68707.1 - 7.4e-05 23.3 5.0 7.4e-05 23.3 3.5 1.8 2 0 0 2 2 2 1 4F5 protein family Chromo PF00385.19 CDJ68708.1 - 1.2e-09 37.6 0.2 1.2e-09 37.6 0.2 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DSPc PF00782.15 CDJ68709.1 - 6.2e-08 32.3 0.0 1.7e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDJ68709.1 - 2.4e-05 23.8 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Maf PF02545.9 CDJ68710.1 - 6.3e-17 61.3 0.1 1.2e-05 24.5 0.0 3.1 3 0 0 3 3 3 3 Maf-like protein DUF2361 PF10153.4 CDJ68711.1 - 4.7e-09 36.4 15.5 4.7e-09 36.4 10.8 3.0 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Coatomer_WDAD PF04053.9 CDJ68712.1 - 1.5e-76 258.0 0.0 6.9e-76 255.8 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 CDJ68712.1 - 1.1e-64 218.6 0.0 1.6e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CDJ68712.1 - 1.7e-38 129.0 4.4 8.4e-11 41.3 0.0 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat TPR_2 PF07719.12 CDJ68712.1 - 0.0082 15.9 3.4 2.1 8.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Nup160 PF11715.3 CDJ68712.1 - 0.012 13.7 6.0 0.46 8.5 0.2 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 CDJ68712.1 - 0.034 13.6 0.0 3.4 7.2 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CDJ68712.1 - 0.051 12.3 0.3 0.54 8.9 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like TPR_11 PF13414.1 CDJ68712.1 - 0.055 13.1 0.3 5.6 6.7 0.0 3.8 4 1 0 4 4 4 0 TPR repeat TPR_16 PF13432.1 CDJ68712.1 - 0.061 14.0 7.5 18 6.1 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_2 PF07724.9 CDJ68713.1 - 1.7e-51 174.5 0.0 5.5e-50 169.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CDJ68713.1 - 3.7e-24 85.4 0.0 1.1e-10 41.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CDJ68713.1 - 3.9e-20 71.5 1.0 1.8e-19 69.3 0.2 2.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 CDJ68713.1 - 5.9e-17 61.3 4.1 3e-09 36.6 0.0 3.7 4 0 0 4 4 2 2 Clp amino terminal domain AAA_5 PF07728.9 CDJ68713.1 - 2.4e-13 50.0 0.1 2.1e-10 40.4 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CDJ68713.1 - 4.6e-08 33.2 0.1 0.0011 19.1 0.0 4.2 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.1 CDJ68713.1 - 1.7e-07 31.2 0.0 0.0072 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CDJ68713.1 - 3.2e-07 29.9 0.0 4.6e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 CDJ68713.1 - 8.6e-07 29.1 15.5 0.017 15.1 0.0 6.5 5 3 1 7 7 6 2 AAA ATPase domain AAA_17 PF13207.1 CDJ68713.1 - 9.7e-07 29.6 3.5 0.0023 18.7 0.1 4.0 2 2 0 3 3 3 2 AAA domain RuvB_N PF05496.7 CDJ68713.1 - 3.6e-05 22.9 0.1 0.0074 15.3 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CDJ68713.1 - 6.1e-05 23.3 1.0 0.022 15.0 0.0 3.6 3 1 1 4 4 4 1 AAA domain Zeta_toxin PF06414.7 CDJ68713.1 - 0.00016 20.8 0.2 0.0028 16.7 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin Arch_ATPase PF01637.13 CDJ68713.1 - 0.00032 20.4 0.9 0.28 10.8 0.0 3.6 3 1 0 4 4 4 1 Archaeal ATPase DNA_pol3_delta2 PF13177.1 CDJ68713.1 - 0.0013 18.3 0.0 0.013 15.2 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 CDJ68713.1 - 0.0017 17.8 1.9 0.013 15.0 0.0 3.0 3 1 0 3 3 3 1 AAA-like domain Sulfatase_C PF14707.1 CDJ68713.1 - 0.003 17.8 0.1 0.0083 16.4 0.1 1.7 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase T2SE PF00437.15 CDJ68713.1 - 0.0038 16.1 0.0 0.0094 14.8 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 CDJ68713.1 - 0.0052 16.2 0.0 0.086 12.2 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.6 CDJ68713.1 - 0.0055 16.2 0.0 0.26 10.8 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CDJ68713.1 - 0.0065 16.4 1.6 1.8 8.4 0.0 4.2 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CDJ68713.1 - 0.012 14.7 0.2 2.8 7.0 0.0 3.3 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 CDJ68713.1 - 0.017 14.0 0.0 0.4 9.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 CDJ68713.1 - 0.018 14.7 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CDJ68713.1 - 0.022 14.9 0.0 0.6 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 CDJ68713.1 - 0.026 14.8 0.0 0.19 12.0 0.0 2.5 3 0 0 3 3 1 0 ABC transporter AAA_19 PF13245.1 CDJ68713.1 - 0.048 13.4 0.0 3.3 7.5 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain DUF87 PF01935.12 CDJ68713.1 - 0.23 11.2 3.4 2 8.1 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function DUF87 Phage_GP20 PF06810.6 CDJ68713.1 - 0.43 9.9 13.0 1.6 8.1 4.5 3.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 APG6 PF04111.7 CDJ68713.1 - 1.8 7.5 10.2 6.9 5.6 3.9 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 YgaB PF14182.1 CDJ68713.1 - 2.9 8.1 12.2 0.09 13.0 2.5 2.9 3 0 0 3 3 2 0 YgaB-like protein AAA_23 PF13476.1 CDJ68713.1 - 7.9 6.7 15.3 9.9 6.4 0.0 3.2 2 1 0 2 2 1 0 AAA domain AAA_12 PF13087.1 CDJ68714.1 - 6.8e-23 81.0 0.0 2.7e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 CDJ68714.1 - 3.4e-14 52.9 0.2 2.8e-08 33.6 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 CDJ68714.1 - 1.9e-10 40.6 2.7 2.5e-09 37.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDJ68714.1 - 2.2e-05 24.0 0.4 2.2e-05 24.0 0.3 3.7 4 0 0 4 4 4 1 Part of AAA domain AAA_16 PF13191.1 CDJ68714.1 - 0.00017 21.6 0.2 0.00017 21.6 0.1 3.7 5 0 0 5 5 4 1 AAA ATPase domain AAA PF00004.24 CDJ68714.1 - 0.0009 19.4 0.0 0.003 17.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CDJ68714.1 - 0.0019 17.8 0.0 0.0049 16.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CDJ68714.1 - 0.01 16.0 0.0 0.053 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CDJ68714.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 CDJ68714.1 - 0.02 14.2 0.0 0.074 12.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 CDJ68714.1 - 0.028 13.4 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 CDJ68714.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 CDJ68714.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CDJ68714.1 - 0.2 12.4 0.1 0.47 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain LRRNT_2 PF08263.7 CDJ68716.1 - 0.063 13.2 2.3 9.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Asn_synthase PF00733.16 CDJ68718.1 - 2.6e-21 76.2 0.1 2e-12 47.1 0.0 2.9 3 0 0 3 3 3 2 Asparagine synthase Lectin_leg-like PF03388.8 CDJ68719.1 - 8.9e-13 47.8 0.2 1.8e-12 46.8 0.1 1.5 1 1 0 1 1 1 1 Legume-like lectin family Got1 PF04178.7 CDJ68720.1 - 1.2e-29 102.8 18.2 1.7e-29 102.3 12.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Kazal_1 PF00050.16 CDJ68721.1 - 4.4e-09 36.2 5.7 6.2e-09 35.7 3.9 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CDJ68721.1 - 1.5e-08 34.4 7.6 2.1e-08 33.9 5.2 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Myb_Cef PF11831.3 CDJ68722.1 - 7.8e-26 90.7 1.0 7.8e-26 90.7 0.7 3.5 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 CDJ68722.1 - 2.7e-18 65.7 12.9 4.4e-11 42.6 0.2 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDJ68722.1 - 5.2e-18 64.9 2.3 5.7e-13 48.7 1.6 4.9 3 2 2 5 5 5 2 Myb-like DNA-binding domain Rap1_C PF11626.3 CDJ68722.1 - 0.06 13.2 7.0 3.9 7.4 0.1 3.8 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Chorein_N PF12624.2 CDJ68723.1 - 1.7e-05 24.3 0.0 3.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CDJ68723.1 - 0.00016 20.9 0.0 0.00072 18.8 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Na_H_antiporter PF03553.9 CDJ68723.1 - 0.025 13.5 0.1 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter family Y_phosphatase PF00102.22 CDJ68723.1 - 1.1 8.5 0.0 2 7.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ndc1_Nup PF09531.5 CDJ68723.1 - 1.4 7.2 2.5 5.6 5.2 1.7 2.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L31e PF01198.14 CDJ68724.1 - 1.6e-36 123.8 4.9 1.6e-36 123.8 3.4 1.3 1 1 0 1 1 1 1 Ribosomal protein L31e DUF4559 PF15112.1 CDJ68724.1 - 0.1 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Rep_fac_C PF08542.6 CDJ68725.1 - 2.5e-10 40.2 0.0 4.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CDJ68725.1 - 0.0021 16.7 0.0 0.16 10.6 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 CDJ68725.1 - 0.016 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.24 CDJ68726.1 - 3.1e-07 30.0 0.2 6.1e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDJ68726.1 - 1.2e-06 28.6 0.1 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CDJ68726.1 - 0.00013 21.6 0.0 0.00013 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CDJ68726.1 - 0.00051 19.9 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 CDJ68726.1 - 0.0013 18.1 0.1 0.003 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDJ68726.1 - 0.0019 17.9 2.1 0.01 15.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 CDJ68726.1 - 0.0036 16.5 0.0 0.0074 15.5 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 CDJ68726.1 - 0.0043 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 CDJ68726.1 - 0.0096 16.2 0.4 0.52 10.6 0.1 2.2 1 1 0 2 2 2 1 ABC transporter SRP54 PF00448.17 CDJ68726.1 - 0.0097 15.3 0.4 0.028 13.8 0.3 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CDJ68726.1 - 0.011 15.6 0.1 0.044 13.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CDJ68726.1 - 0.012 15.0 0.0 0.2 11.0 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 CDJ68726.1 - 0.024 13.7 0.2 0.098 11.7 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin DAP3 PF10236.4 CDJ68726.1 - 0.025 13.5 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CDJ68726.1 - 0.027 14.4 0.1 0.052 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CDJ68726.1 - 0.027 14.1 0.1 0.067 12.8 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 CDJ68726.1 - 0.03 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CDJ68726.1 - 0.048 12.5 0.0 0.059 12.2 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 CDJ68726.1 - 0.074 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 CDJ68726.1 - 0.12 12.2 0.0 0.97 9.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CDJ68726.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 CDJ68726.1 - 0.15 10.6 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 CDJ68726.1 - 0.23 11.7 0.0 0.34 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.5 CDJ68728.1 - 0.00035 20.3 0.0 0.00088 19.1 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain CAP_N PF01213.14 CDJ68728.1 - 0.25 10.6 2.6 0.44 9.7 1.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Stm1_N PF09598.5 CDJ68728.1 - 5 7.8 8.7 4 8.2 2.6 2.8 2 0 0 2 2 2 0 Stm1 Myosin_head PF00063.16 CDJ68729.1 - 0.00019 19.6 0.0 0.00022 19.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_head PF00063.16 CDJ68730.1 - 6.2e-96 322.0 0.0 7.2e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 CDJ68730.1 - 0.015 15.4 0.1 0.036 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CDJ68730.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CDJ68730.1 - 0.057 13.1 0.0 0.82 9.4 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 CDJ68730.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 CDJ68730.1 - 0.14 12.3 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Myosin_head PF00063.16 CDJ68731.1 - 1.3e-60 205.2 0.0 3.2e-60 203.9 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Dynein_light PF01221.13 CDJ68731.1 - 0.0031 17.4 0.9 0.0078 16.1 0.0 2.1 2 0 0 2 2 2 1 Dynein light chain type 1 U1snRNP70_N PF12220.3 CDJ68731.1 - 0.065 13.5 3.9 0.16 12.3 2.7 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RNase_T PF00929.19 CDJ68732.1 - 7.3e-18 65.3 0.0 1.2e-17 64.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Ctr PF04145.10 CDJ68732.1 - 2.5 8.1 6.9 17 5.4 0.0 3.3 4 1 0 4 4 4 0 Ctr copper transporter family K_channel_TID PF07941.6 CDJ68733.1 - 1.3 9.2 12.3 2.5 8.4 8.6 1.4 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Creatininase PF02633.9 CDJ68734.1 - 0.55 9.2 4.2 0.93 8.5 0.0 2.1 2 0 0 2 2 2 0 Creatinine amidohydrolase Rifin_STEVOR PF02009.11 CDJ68734.1 - 1.1 8.8 3.6 1.4 8.4 2.5 1.2 1 0 0 1 1 1 0 Rifin/stevor family DNA_pol_viral_N PF00242.12 CDJ68734.1 - 1.3 7.9 14.7 1.5 7.7 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Claudin_2 PF13903.1 CDJ68735.1 - 0.94 9.1 0.0 0.94 9.1 0.0 3.6 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction UPF0182 PF03699.8 CDJ68735.1 - 3 5.6 9.2 4.8 4.9 6.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4414 PF14377.1 CDJ68736.1 - 2.5 8.0 17.8 5 7.0 12.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) DUF3353 PF11833.3 CDJ68736.1 - 3.9 6.8 6.4 4.8 6.5 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) BTV_NS2 PF04514.7 CDJ68736.1 - 5.4 5.7 9.2 6.1 5.6 6.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDK2AP PF09806.4 CDJ68737.1 - 0.023 14.9 0.4 0.023 14.9 0.2 2.3 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein ATP12 PF07542.6 CDJ68738.1 - 1.2e-06 28.4 8.8 5.4e-05 23.1 6.1 2.7 1 1 0 1 1 1 1 ATP12 chaperone protein CAF-1_p150 PF11600.3 CDJ68738.1 - 0.61 9.4 12.8 1.6 8.0 8.8 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF45 PF01863.12 CDJ68738.1 - 0.64 9.7 5.5 1.2 8.8 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 AAA_23 PF13476.1 CDJ68738.1 - 2 8.7 7.4 3.7 7.8 5.1 1.4 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDJ68738.1 - 3.8 6.9 22.8 2 7.8 9.0 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ68739.1 - 0.0099 15.3 9.3 0.0099 15.3 6.5 4.1 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein SoxE PF06525.6 CDJ68739.1 - 0.31 10.2 2.0 7.1 5.8 0.2 2.4 2 0 0 2 2 2 0 Sulfocyanin (SoxE) EphA2_TM PF14575.1 CDJ68739.1 - 1.7 9.0 5.5 57 4.2 0.1 4.3 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_S64 PF08192.6 CDJ68739.1 - 5.9 5.0 12.6 2.8 6.1 6.9 1.8 2 0 0 2 2 2 0 Peptidase family S64 Aminotran_1_2 PF00155.16 CDJ68740.1 - 0.47 9.3 4.2 0.76 8.6 2.9 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2413 PF10310.4 CDJ68740.1 - 0.58 8.9 12.3 0.72 8.6 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Macoilin PF09726.4 CDJ68740.1 - 4.6 5.3 20.4 5.6 5.1 14.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4386 PF14329.1 CDJ68741.1 - 0.0044 16.5 6.4 0.005 16.3 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) DUF4456 PF14644.1 CDJ68741.1 - 0.067 12.4 2.4 0.075 12.2 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) DUF3617 PF12276.3 CDJ68741.1 - 0.15 11.5 8.4 0.17 11.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Med15 PF09606.5 CDJ68741.1 - 0.34 9.0 11.7 0.34 9.0 8.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal R_equi_Vir PF05526.6 CDJ68741.1 - 0.95 9.0 7.2 1 8.9 5.0 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF3450 PF11932.3 CDJ68741.1 - 2 7.6 11.3 2.4 7.3 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4630 PF15443.1 CDJ68741.1 - 3 7.6 15.7 3.6 7.3 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Ligase_CoA PF00549.14 CDJ68741.1 - 5.5 6.5 6.8 6.2 6.4 4.7 1.1 1 0 0 1 1 1 0 CoA-ligase DOR PF14839.1 CDJ68741.1 - 6.2 6.5 7.9 7 6.3 5.5 1.1 1 0 0 1 1 1 0 DOR family SR-25 PF10500.4 CDJ68742.1 - 1e-05 25.1 35.6 0.0041 16.6 13.4 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein TTL PF03133.10 CDJ68742.1 - 0.00074 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Transposase_24 PF03004.9 CDJ68742.1 - 0.61 9.9 8.6 0.66 9.8 2.2 2.5 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Utp14 PF04615.8 CDJ68742.1 - 6.4 4.8 13.7 8.5 4.3 9.5 1.1 1 0 0 1 1 1 0 Utp14 protein TraG-D_C PF12696.2 CDJ68742.1 - 7.1 6.5 7.3 3.6 7.4 1.7 2.3 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF755 PF05501.6 CDJ68742.1 - 8.1 6.5 35.6 11 6.1 13.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) TMEM154 PF15102.1 CDJ68744.1 - 0.012 15.3 1.6 0.025 14.3 0.2 2.3 2 0 0 2 2 2 0 TMEM154 protein family MRAP PF15183.1 CDJ68744.1 - 0.071 12.7 0.9 0.34 10.5 0.2 2.4 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family SR-25 PF10500.4 CDJ68744.1 - 0.41 10.0 13.2 0.013 15.0 3.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sugar_tr PF00083.19 CDJ68745.1 - 1.4e-12 46.9 40.0 8.3e-12 44.4 4.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 CDJ68745.1 - 1e-05 24.4 48.8 1e-05 24.4 33.8 4.1 2 2 2 4 4 4 2 Major Facilitator Superfamily LMBR1 PF04791.11 CDJ68746.1 - 1.8 7.0 9.9 4.5 5.7 0.0 2.6 2 1 0 2 2 2 0 LMBR1-like membrane protein DUF1117 PF06547.7 CDJ68746.1 - 6.1 6.9 13.4 23 5.1 1.6 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Macoilin PF09726.4 CDJ68747.1 - 1.1 7.4 16.3 1.3 7.1 11.3 1.1 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 CDJ68747.1 - 2.7 7.3 35.2 23 4.3 24.2 2.2 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ68748.1 - 1.6e-06 27.8 17.7 1.9e-06 27.4 12.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ68748.1 - 0.0046 16.3 14.9 0.0059 16.0 10.3 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PRP1_N PF06424.7 CDJ68748.1 - 0.015 15.6 5.7 0.019 15.2 4.0 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal FlxA PF14282.1 CDJ68748.1 - 0.021 14.7 52.2 0.026 14.4 36.2 1.1 1 0 0 1 1 1 0 FlxA-like protein Corona_nucleoca PF00937.13 CDJ68748.1 - 0.032 13.1 19.4 0.037 12.9 13.4 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PAT1 PF09770.4 CDJ68748.1 - 0.19 9.9 29.1 0.19 9.9 20.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dsh_C PF12316.3 CDJ68748.1 - 0.21 11.6 16.7 0.23 11.5 11.5 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF2217 PF10265.4 CDJ68748.1 - 0.25 10.0 10.2 0.28 9.9 7.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Gastrin PF00918.12 CDJ68748.1 - 0.25 12.1 15.7 0.32 11.7 10.9 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family SprA-related PF12118.3 CDJ68748.1 - 0.31 10.3 27.7 0.35 10.1 19.2 1.1 1 0 0 1 1 1 0 SprA-related family RAP1 PF07218.6 CDJ68748.1 - 0.45 8.5 4.0 0.42 8.6 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) G6PD_N PF00479.17 CDJ68748.1 - 0.49 10.6 7.5 0.59 10.3 5.2 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Herpes_UL87 PF03043.9 CDJ68748.1 - 0.6 8.4 7.7 0.7 8.2 5.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family CDC45 PF02724.9 CDJ68748.1 - 0.94 7.4 11.3 1 7.2 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein AAA_23 PF13476.1 CDJ68748.1 - 1.1 9.5 13.8 1.4 9.2 9.6 1.3 1 0 0 1 1 1 0 AAA domain Raftlin PF15250.1 CDJ68748.1 - 1.1 7.6 14.5 1.4 7.4 10.1 1.0 1 0 0 1 1 1 0 Raftlin YlbD_coat PF14071.1 CDJ68748.1 - 1.5 8.8 18.8 1.8 8.6 13.0 1.1 1 0 0 1 1 1 0 Putative coat protein DUF4228 PF14009.1 CDJ68748.1 - 1.6 8.7 13.6 2 8.5 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) NPR3 PF03666.8 CDJ68748.1 - 1.7 7.0 13.4 2.2 6.7 9.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAGA-Tad1 PF12767.2 CDJ68748.1 - 1.9 8.0 18.5 2.2 7.9 12.8 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3446 PF11928.3 CDJ68748.1 - 2.1 8.6 18.8 0.15 12.2 9.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) RR_TM4-6 PF06459.7 CDJ68748.1 - 2.1 8.1 9.2 2.5 7.9 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1117 PF06547.7 CDJ68748.1 - 2.1 8.4 6.5 3.6 7.7 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Myco_19_kDa PF05481.7 CDJ68748.1 - 2.7 7.7 7.1 3.7 7.3 4.9 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen DUF2201_N PF13203.1 CDJ68748.1 - 2.8 7.0 18.9 3 6.9 13.1 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Cyclin_C PF02984.14 CDJ68748.1 - 3.3 7.6 7.9 4.4 7.2 5.4 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain DOR PF14839.1 CDJ68748.1 - 3.3 7.3 19.2 4.9 6.8 13.3 1.3 1 0 0 1 1 1 0 DOR family DUF853 PF05872.7 CDJ68748.1 - 3.9 5.7 10.0 4.9 5.3 6.9 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Activator_LAG-3 PF11498.3 CDJ68748.1 - 4.4 5.9 42.4 5.4 5.6 29.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GET2 PF08690.5 CDJ68748.1 - 4.4 6.4 17.6 5.3 6.1 12.2 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3450 PF11932.3 CDJ68748.1 - 4.4 6.4 23.8 5.3 6.2 16.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SID-1_RNA_chan PF13965.1 CDJ68748.1 - 4.5 5.3 9.4 5.4 5.0 6.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDK5_activator PF03261.10 CDJ68748.1 - 5.9 6.1 15.9 6.9 5.8 11.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF1501 PF07394.7 CDJ68748.1 - 5.9 5.6 14.4 6.8 5.4 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) OmpH PF03938.9 CDJ68748.1 - 9.3 6.1 30.0 12 5.8 20.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spt20 PF12090.3 CDJ68749.1 - 0.079 12.3 9.4 2.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Spt20 family HdeA PF06411.6 CDJ68749.1 - 0.16 11.9 0.9 0.41 10.6 0.7 1.6 1 0 0 1 1 1 0 HdeA/HdeB family CIAPIN1 PF05093.8 CDJ68749.1 - 0.51 10.4 8.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis IncA PF04156.9 CDJ68749.1 - 3.1 7.3 17.8 0.49 9.9 5.6 2.3 2 0 0 2 2 2 0 IncA protein DUF2681 PF10883.3 CDJ68749.1 - 5.7 7.2 21.0 0.52 10.5 5.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Ndc1_Nup PF09531.5 CDJ68750.1 - 0.0014 17.1 4.6 0.0022 16.5 3.2 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF2370 PF10176.4 CDJ68750.1 - 0.029 13.7 3.9 0.051 12.8 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Activator_LAG-3 PF11498.3 CDJ68750.1 - 0.17 10.5 25.6 0.24 10.0 17.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RAB3GAP2_N PF14655.1 CDJ68750.1 - 0.34 9.8 4.9 0.57 9.1 3.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PAT1 PF09770.4 CDJ68750.1 - 0.92 7.6 26.6 1.2 7.2 18.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 CDJ68750.1 - 1.1 8.5 7.8 1.5 8.0 5.4 1.1 1 0 0 1 1 1 0 Spt20 family Hid1 PF12722.2 CDJ68750.1 - 3 5.3 4.9 3.8 5.0 3.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4557 PF15101.1 CDJ68750.1 - 3.8 7.2 11.6 6.1 6.6 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CDK5_activator PF03261.10 CDJ68750.1 - 4.1 6.6 7.6 11 5.2 5.4 1.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Suf PF05843.9 CDJ68750.1 - 6.2 6.4 11.0 8.6 6.0 7.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MCPVI PF02993.9 CDJ68750.1 - 6.6 6.8 17.0 0.33 11.0 7.7 1.8 2 0 0 2 2 2 0 Minor capsid protein VI SAGA-Tad1 PF12767.2 CDJ68751.1 - 9 5.8 15.9 16 5.0 11.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Pkinase PF00069.20 CDJ68752.1 - 4.7e-28 98.0 0.0 2.2e-14 53.2 0.0 3.7 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68752.1 - 1.2e-11 44.1 0.0 7.1e-07 28.5 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase DUF572 PF04502.8 CDJ68752.1 - 0.11 11.7 20.1 0.019 14.2 8.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) CDC45 PF02724.9 CDJ68752.1 - 0.19 9.7 12.9 0.33 8.9 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.6 CDJ68752.1 - 0.48 9.5 9.0 0.1 11.7 3.9 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PIH1 PF08190.7 CDJ68752.1 - 2.3 7.5 12.6 3.9 6.8 8.7 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Pex16 PF08610.5 CDJ68752.1 - 6.1 5.7 12.8 9.4 5.1 8.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Suf PF05843.9 CDJ68752.1 - 8.3 6.0 11.3 15 5.1 7.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DivIC PF04977.10 CDJ68752.1 - 8.3 5.9 15.4 14 5.2 10.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Ycf1 PF05758.7 CDJ68752.1 - 8.6 3.9 9.7 11 3.5 6.7 1.1 1 0 0 1 1 1 0 Ycf1 RRM_1 PF00076.17 CDJ68753.1 - 3.8e-54 180.2 0.0 2.1e-18 65.7 0.0 8.6 8 0 0 8 8 8 7 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ68753.1 - 1.8e-50 168.8 0.4 2.2e-14 53.1 0.0 6.4 6 2 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ68753.1 - 9.2e-38 127.8 0.4 9.6e-11 41.3 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FimP PF09766.4 CDJ68753.1 - 0.0047 16.0 11.6 0.0047 16.0 8.0 3.3 3 0 0 3 3 3 2 Fms-interacting protein Pex14_N PF04695.8 CDJ68753.1 - 0.0098 15.9 5.4 0.0098 15.9 3.7 6.0 5 1 0 5 5 5 2 Peroxisomal membrane anchor protein (Pex14p) conserved region BRF1 PF07741.8 CDJ68753.1 - 0.013 15.6 6.9 0.013 15.6 4.8 7.7 6 2 0 6 6 6 0 Brf1-like TBP-binding domain Suf PF05843.9 CDJ68753.1 - 0.06 13.0 54.7 0.013 15.2 7.3 4.0 3 1 0 4 4 4 0 Suppressor of forked protein (Suf) DUF221 PF02714.10 CDJ68753.1 - 0.32 9.8 0.0 24 3.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF221 DUF4647 PF15504.1 CDJ68753.1 - 7.7 5.2 37.8 1.1 8.0 5.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4647) LRR_4 PF12799.2 CDJ68754.1 - 1.2e-14 53.5 14.1 3.8e-06 26.3 0.6 4.5 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ68754.1 - 2e-09 37.0 9.7 9.9e-06 25.2 0.5 4.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CDJ68754.1 - 2.2e-08 33.0 8.6 3.3 8.0 0.0 6.4 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 CDJ68754.1 - 5.5e-08 31.7 13.5 3.3 8.3 0.0 7.3 8 0 0 8 8 6 1 Leucine rich repeat LRR_6 PF13516.1 CDJ68754.1 - 1.1e-07 31.2 6.0 5.2 7.4 0.1 6.8 7 0 0 7 7 7 1 Leucine Rich repeat LRR_9 PF14580.1 CDJ68754.1 - 3.1e-05 23.6 0.2 0.1 12.1 0.0 3.3 3 0 0 3 3 3 1 Leucine-rich repeat BAF1_ABF1 PF04684.8 CDJ68754.1 - 0.00079 18.3 22.3 0.00079 18.3 15.4 5.1 5 1 0 5 5 3 1 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CDJ68754.1 - 0.0089 15.3 11.4 0.53 9.5 0.2 2.2 2 0 0 2 2 2 2 Spt20 family EPL1 PF10513.4 CDJ68754.1 - 0.012 15.9 7.2 0.21 11.8 2.5 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like DDHD PF02862.12 CDJ68754.1 - 0.03 14.1 7.9 0.98 9.1 3.8 2.6 3 0 0 3 3 3 0 DDHD domain Suf PF05843.9 CDJ68754.1 - 0.031 14.0 13.5 0.69 9.5 0.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SOBP PF15279.1 CDJ68754.1 - 0.068 13.5 9.3 0.29 11.4 4.4 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Gti1_Pac2 PF09729.4 CDJ68754.1 - 0.076 12.8 1.6 0.39 10.5 0.1 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family FimP PF09766.4 CDJ68754.1 - 0.21 10.6 24.1 0.34 9.9 8.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF4647 PF15504.1 CDJ68754.1 - 0.82 8.4 14.9 1.3 7.8 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) FAM176 PF14851.1 CDJ68754.1 - 1.6 8.3 5.1 2 8.0 0.6 2.3 2 0 0 2 2 2 0 FAM176 family eIF-3_zeta PF05091.7 CDJ68754.1 - 1.8 7.0 16.0 1.5 7.3 5.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.8 CDJ68754.1 - 2.7 7.4 14.0 14 5.0 6.9 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain HlyD_2 PF12700.2 CDJ68754.1 - 2.7 7.0 10.4 1.2 8.1 3.4 2.1 2 0 0 2 2 2 0 HlyD family secretion protein RAB3GAP2_N PF14655.1 CDJ68754.1 - 2.8 6.8 18.2 3.5 6.5 5.9 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_23 PF13476.1 CDJ68754.1 - 3.7 7.8 13.6 4.6 7.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain FAM60A PF15396.1 CDJ68754.1 - 3.7 7.2 7.9 4.5 6.9 3.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Baculo_PP31 PF05311.6 CDJ68754.1 - 6.4 5.9 13.2 0.74 9.0 4.8 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Hid1 PF12722.2 CDJ68754.1 - 7.4 4.1 10.8 1.4 6.5 3.8 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Maf1 PF09174.5 CDJ68754.1 - 8.2 6.2 8.6 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Maf1 regulator Pex16 PF08610.5 CDJ68754.1 - 8.8 5.2 13.7 2 7.3 4.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) CRF1 PF10380.4 CDJ68754.1 - 9 6.6 8.9 6.8 7.0 2.6 2.4 2 0 0 2 2 2 0 Transcription factor CRF1 FAM220 PF15487.1 CDJ68755.1 - 0.033 13.5 1.5 0.093 12.0 1.0 1.7 1 0 0 1 1 1 0 FAM220 family AP2 PF00847.15 CDJ68755.1 - 0.049 13.7 0.0 0.049 13.7 0.0 4.6 5 1 1 6 6 6 0 AP2 domain Dus PF01207.12 CDJ68756.1 - 3.7e-12 45.7 0.2 4.4e-11 42.1 0.0 2.4 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) DUF3446 PF11928.3 CDJ68756.1 - 0.00027 21.0 16.9 0.0079 16.3 5.6 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3446) SR-25 PF10500.4 CDJ68756.1 - 0.00082 18.9 4.0 0.00082 18.9 2.8 3.0 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein IMPDH PF00478.20 CDJ68756.1 - 0.054 12.3 0.1 0.08 11.8 0.1 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Alpha-amylase PF00128.19 CDJ68756.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Apt1 PF10351.4 CDJ68756.1 - 1.2 7.8 2.8 1.6 7.4 2.0 1.3 1 1 0 1 1 1 0 Golgi-body localisation protein domain DUF1645 PF07816.6 CDJ68756.1 - 3 8.2 17.7 0.79 10.1 3.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) Herpes_capsid PF06112.6 CDJ68756.1 - 4.6 7.2 16.8 3.3 7.7 4.8 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ACPS PF01648.15 CDJ68757.1 - 4.2e-09 36.2 0.0 9.3e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GDPD PF03009.12 CDJ68758.1 - 3.5e-06 26.7 0.0 5.8e-05 22.7 0.0 2.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SR-25 PF10500.4 CDJ68758.1 - 2.8 7.3 20.8 4.1 6.8 14.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IncA PF04156.9 CDJ68759.1 - 0.017 14.7 0.9 0.017 14.7 0.6 6.0 3 2 2 5 5 5 0 IncA protein HemY_N PF07219.8 CDJ68760.1 - 0.096 12.2 0.2 0.096 12.2 0.2 2.6 4 0 0 4 4 4 0 HemY protein N-terminus MRAP PF15183.1 CDJ68760.1 - 0.21 11.1 1.5 2.4 7.8 0.1 2.4 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF3357 PF11837.3 CDJ68760.1 - 0.87 9.4 6.2 2 8.2 0.1 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF3357) Ribosomal_60s PF00428.14 CDJ68760.1 - 1.4 9.3 24.5 0.29 11.5 3.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein AP2 PF00847.15 CDJ68762.1 - 9.2e-05 22.5 0.3 9.2e-05 22.5 0.2 3.6 5 0 0 5 5 5 1 AP2 domain DnaJ-X PF14308.1 CDJ68763.1 - 2.3e-52 177.2 7.2 2.3e-52 177.2 5.0 3.1 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 CDJ68763.1 - 1.8e-25 88.4 0.8 4.6e-25 87.1 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain Spt20 PF12090.3 CDJ68763.1 - 9 5.5 23.5 8.9 5.6 0.6 4.2 4 0 0 4 4 4 0 Spt20 family LUC7 PF03194.10 CDJ68764.1 - 1.3e-35 123.1 1.1 1.7e-35 122.8 0.8 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Occludin_ELL PF07303.8 CDJ68764.1 - 0.0025 18.4 4.8 0.01 16.5 3.5 1.9 1 1 1 2 2 2 1 Occludin homology domain Meth_synt_2 PF01717.13 CDJ68764.1 - 0.011 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Phyto_Pns9_10 PF05878.6 CDJ68764.1 - 0.025 13.5 0.2 0.041 12.8 0.1 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF603 PF04645.7 CDJ68764.1 - 0.029 14.3 1.3 0.051 13.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF603 NPV_P10 PF05531.7 CDJ68764.1 - 0.038 14.2 3.5 3.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.7 CDJ68764.1 - 0.042 13.4 1.1 0.16 11.5 0.7 2.0 1 1 0 1 1 1 0 Heat shock factor binding protein 1 IncA PF04156.9 CDJ68764.1 - 0.074 12.6 4.8 0.12 11.9 3.4 1.2 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 CDJ68764.1 - 0.083 12.6 5.9 0.5 10.0 4.0 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FCD PF07729.7 CDJ68764.1 - 0.09 13.1 0.8 0.18 12.1 0.5 1.6 1 1 0 1 1 1 0 FCD domain ADIP PF11559.3 CDJ68764.1 - 0.12 12.2 6.4 0.55 10.1 2.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FliJ PF02050.11 CDJ68764.1 - 0.12 12.3 6.1 0.28 11.2 0.3 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein Ran-binding PF05508.6 CDJ68764.1 - 0.13 11.1 1.0 0.18 10.6 0.7 1.2 1 0 0 1 1 1 0 RanGTP-binding protein TnpV PF14198.1 CDJ68764.1 - 0.18 11.7 1.9 0.34 10.8 1.3 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV HSCB_C PF07743.8 CDJ68764.1 - 0.24 11.9 6.4 1.1 9.8 4.2 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4164 PF13747.1 CDJ68764.1 - 0.24 11.5 7.7 0.32 11.1 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ISG65-75 PF11727.3 CDJ68764.1 - 0.34 9.9 2.0 0.56 9.2 1.0 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein Mnd1 PF03962.10 CDJ68764.1 - 0.43 10.2 5.3 0.89 9.1 3.6 1.5 1 1 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 CDJ68764.1 - 0.59 7.9 2.9 0.88 7.3 1.3 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 CDJ68764.1 - 0.78 9.6 13.1 5.7 6.8 1.3 3.3 3 0 0 3 3 3 0 Basic region leucine zipper bZIP_Maf PF03131.12 CDJ68764.1 - 0.83 9.9 5.5 1.9 8.8 2.0 2.3 1 1 0 2 2 2 0 bZIP Maf transcription factor SlyX PF04102.7 CDJ68764.1 - 0.85 10.0 6.6 16 5.9 0.0 2.7 2 1 0 2 2 2 0 SlyX DUF1192 PF06698.6 CDJ68764.1 - 1.7 8.5 4.3 5 7.0 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Mst1_SARAH PF11629.3 CDJ68764.1 - 2.1 8.2 4.9 0.62 9.9 0.3 2.2 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF972 PF06156.8 CDJ68764.1 - 4.9 7.5 6.7 33 4.8 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CDJ68764.1 - 7.3 6.1 8.3 15 5.1 0.1 2.7 2 1 1 3 3 3 0 Septum formation initiator SR-25 PF10500.4 CDJ68765.1 - 0.00016 21.2 13.1 0.00016 21.2 9.1 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CDJ68765.1 - 0.24 11.6 9.6 3.1 7.9 3.3 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Myco_19_kDa PF05481.7 CDJ68765.1 - 2.7 7.8 14.4 3 7.6 2.7 2.1 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen Secretin_N_2 PF07655.8 CDJ68765.1 - 2.8 8.3 16.9 7.6 6.9 2.0 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Chorion_2 PF03964.10 CDJ68765.1 - 3.1 8.3 15.2 3.8 8.0 2.5 2.3 2 0 0 2 2 2 0 Chorion family 2 APC_CDC26 PF10471.4 CDJ68765.1 - 7.1 7.4 9.1 1.9 9.2 3.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 MRP-S26 PF14943.1 CDJ68767.1 - 0.082 12.4 12.3 0.18 11.3 8.5 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF1003 PF06210.6 CDJ68767.1 - 2.5 8.0 8.1 5.3 7.0 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DUF3402 PF11882.3 CDJ68767.1 - 7.1 5.5 7.8 39 3.1 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) SR-25 PF10500.4 CDJ68770.1 - 0.0037 16.7 7.0 0.0037 16.7 4.9 6.8 2 1 3 6 6 6 1 Nuclear RNA-splicing-associated protein ubiquitin PF00240.18 CDJ68771.1 - 2.1e-17 62.2 0.1 2.4e-17 62.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDJ68771.1 - 1.3e-09 37.5 0.1 1.4e-09 37.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDJ68771.1 - 5.2e-05 23.4 0.3 0.00019 21.6 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 CDJ68771.1 - 0.0037 17.4 0.0 0.0041 17.2 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain SAGA-Tad1 PF12767.2 CDJ68772.1 - 0.14 11.8 18.7 0.17 11.5 13.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CAF-1_p150 PF11600.3 CDJ68772.1 - 0.4 10.0 20.2 0.52 9.6 14.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal V_ATPase_I PF01496.14 CDJ68772.1 - 0.78 7.5 3.6 0.86 7.3 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 CDJ68772.1 - 1.5 7.3 6.0 1.6 7.2 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.1 CDJ68772.1 - 1.5 9.1 19.0 1.8 8.8 13.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Corona_nucleoca PF00937.13 CDJ68772.1 - 4.4 6.1 22.6 5.8 5.7 15.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med15 PF09606.5 CDJ68772.1 - 5.1 5.1 41.7 6.7 4.7 28.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDJ68772.1 - 5.1 6.8 12.9 6.4 6.5 8.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_M16 PF00675.15 CDJ68774.1 - 4.4e-05 23.2 3.7 0.00024 20.8 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Apt1 PF10351.4 CDJ68774.1 - 0.034 13.0 4.2 0.46 9.2 0.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ins_P5_2-kin PF06090.7 CDJ68774.1 - 0.078 12.0 7.3 0.12 11.4 5.1 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase DAHP_synth_2 PF01474.11 CDJ68775.1 - 1.9e-50 171.5 0.0 2.7e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF1183 PF06682.7 CDJ68775.1 - 3.3 7.2 14.6 3.3 7.2 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Cwf_Cwc_15 PF04889.7 CDJ68775.1 - 7 6.2 12.2 0.56 9.8 2.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Thioredoxin PF00085.15 CDJ68776.1 - 1.8e-13 50.0 0.0 9.9e-06 25.1 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 CDJ68776.1 - 3.2e-10 40.1 0.0 1.1e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain DUF2681 PF10883.3 CDJ68777.1 - 0.0066 16.6 5.1 0.0066 16.6 3.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) Peptidase_S49_N PF08496.5 CDJ68777.1 - 2.6 7.8 9.2 3.4 7.4 1.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Na_trans_assoc PF06512.8 CDJ68777.1 - 8.4 6.2 11.2 13 5.6 7.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Aminotran_1_2 PF00155.16 CDJ68778.1 - 4.7e-54 183.7 0.0 9.7e-49 166.2 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Macoilin PF09726.4 CDJ68779.1 - 6.1e-05 21.5 32.9 0.00071 18.0 0.3 2.1 2 0 0 2 2 2 2 Transmembrane protein DUF605 PF04652.11 CDJ68779.1 - 0.00063 19.2 2.2 0.00063 19.2 1.5 2.7 2 1 1 3 3 3 1 Vta1 like SPX PF03105.14 CDJ68779.1 - 0.00093 19.0 0.6 0.00093 19.0 0.4 2.4 2 1 0 2 2 2 1 SPX domain Gag_spuma PF03276.9 CDJ68779.1 - 0.23 9.7 8.2 0.72 8.1 2.8 2.3 2 0 0 2 2 2 0 Spumavirus gag protein Cwf_Cwc_15 PF04889.7 CDJ68779.1 - 0.44 10.2 19.2 1.1 8.9 3.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mem_trans PF03547.13 CDJ68779.1 - 0.47 8.6 14.8 2.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Membrane transport protein Ctr PF04145.10 CDJ68779.1 - 0.66 10.0 6.4 6.2 6.8 0.7 3.4 3 0 0 3 3 3 0 Ctr copper transporter family DUF572 PF04502.8 CDJ68779.1 - 2.3 7.3 26.1 2.9 7.0 5.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF1510 PF07423.6 CDJ68779.1 - 3.4 6.9 21.3 0.043 13.1 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Androgen_recep PF02166.11 CDJ68780.1 - 0.087 11.6 13.7 0.11 11.3 9.5 1.1 1 0 0 1 1 1 0 Androgen receptor Phostensin_N PF13916.1 CDJ68780.1 - 0.11 12.4 4.3 0.18 11.8 3.0 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Spt20 PF12090.3 CDJ68780.1 - 0.14 11.5 0.8 0.13 11.6 0.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF2076 PF09849.4 CDJ68780.1 - 1.2 9.1 12.3 1.4 8.9 8.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) APC_CDC26 PF10471.4 CDJ68780.1 - 1.3 9.7 9.2 2 9.2 6.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1183 PF06682.7 CDJ68780.1 - 1.4 8.4 7.7 1.7 8.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) PDE6_gamma PF04868.7 CDJ68780.1 - 2.4 8.0 5.4 30 4.5 0.0 2.1 1 1 1 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit FCP1_C PF09309.5 CDJ68780.1 - 2.8 7.1 6.9 4.1 6.6 4.8 1.2 1 0 0 1 1 1 0 FCP1, C-terminal PAT1 PF09770.4 CDJ68780.1 - 3.1 5.9 16.7 3.3 5.8 11.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dishevelled PF02377.10 CDJ68780.1 - 5.3 7.3 8.8 9.9 6.4 6.1 1.5 1 0 0 1 1 1 0 Dishevelled specific domain PHD_3 PF13922.1 CDJ68780.1 - 9.2 6.5 6.8 15 5.9 4.7 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF2756 PF10956.3 CDJ68781.1 - 0.024 14.8 10.0 0.03 14.5 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Enterotoxin_a PF01375.12 CDJ68781.1 - 0.071 12.4 3.4 0.089 12.0 2.3 1.0 1 0 0 1 1 1 0 Heat-labile enterotoxin alpha chain OATP PF03137.15 CDJ68781.1 - 0.12 10.3 0.1 0.14 10.2 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PUA_2 PF14306.1 CDJ68781.1 - 0.18 11.1 0.8 0.24 10.8 0.6 1.2 1 0 0 1 1 1 0 PUA-like domain Gastrin PF00918.12 CDJ68781.1 - 0.45 11.3 6.6 0.55 11.0 4.6 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DOR PF14839.1 CDJ68781.1 - 0.91 9.2 4.2 1 9.0 2.9 1.1 1 0 0 1 1 1 0 DOR family PP2C_2 PF13672.1 CDJ68781.1 - 1.6 8.0 7.4 2 7.7 5.1 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C eIF-4B PF06273.6 CDJ68781.1 - 1.9 7.1 4.9 2.1 6.9 3.4 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B APH PF01636.18 CDJ68781.1 - 3 7.5 7.2 3.6 7.2 5.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family CPSF100_C PF13299.1 CDJ68782.1 - 0.00016 21.9 5.1 0.00026 21.1 3.5 1.3 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.3 CDJ68782.1 - 0.00048 18.8 4.5 0.00056 18.6 3.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF3548 PF12068.3 CDJ68782.1 - 0.0038 16.5 2.0 0.0081 15.4 1.3 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3548) Methyltrn_RNA_2 PF04013.7 CDJ68782.1 - 0.006 16.1 0.3 0.012 15.1 0.1 1.6 1 1 0 1 1 1 1 Putative SAM-dependent RNA methyltransferase CDC45 PF02724.9 CDJ68782.1 - 0.032 12.2 5.2 0.032 12.2 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Med13_N PF11597.3 CDJ68782.1 - 0.049 12.3 5.4 0.075 11.7 3.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal AUX_IAA PF02309.11 CDJ68782.1 - 0.068 12.9 6.4 0.11 12.2 4.4 1.4 1 0 0 1 1 1 0 AUX/IAA family DUF3353 PF11833.3 CDJ68782.1 - 0.09 12.2 0.6 0.13 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) NARP1 PF12569.3 CDJ68782.1 - 0.24 10.1 12.2 0.31 9.7 8.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ASFV_J13L PF05568.6 CDJ68782.1 - 0.24 10.9 1.7 0.36 10.3 1.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein FGF-BP1 PF06473.7 CDJ68782.1 - 0.44 10.0 12.4 0.81 9.2 8.6 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Zip PF02535.17 CDJ68782.1 - 0.54 9.2 2.1 0.65 8.9 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_polI_A34 PF08208.6 CDJ68782.1 - 0.72 9.4 18.8 1.4 8.5 13.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Adaptin_binding PF10199.4 CDJ68782.1 - 0.76 10.0 15.2 0.44 10.8 8.6 1.8 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Suf PF05843.9 CDJ68782.1 - 0.94 9.1 7.7 1.3 8.6 5.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ycf1 PF05758.7 CDJ68782.1 - 0.97 7.0 5.2 0.86 7.2 3.6 1.1 1 0 0 1 1 1 0 Ycf1 UPF0560 PF10577.4 CDJ68782.1 - 1.2 7.3 8.9 1.5 7.0 6.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3464 PF11947.3 CDJ68782.1 - 1.6 8.1 7.6 2.5 7.5 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) MRI PF15325.1 CDJ68782.1 - 1.9 9.4 10.8 3.9 8.4 7.5 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF3987 PF13148.1 CDJ68782.1 - 2.2 6.7 9.4 3.5 6.0 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AIF_C PF14721.1 CDJ68782.1 - 2.5 8.3 6.1 4.1 7.6 4.2 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1510 PF07423.6 CDJ68782.1 - 3.6 6.8 17.2 5.6 6.2 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pap_E4 PF02711.9 CDJ68782.1 - 4.1 8.2 6.7 11 6.9 4.6 1.9 1 1 0 1 1 1 0 E4 protein Vfa1 PF08432.5 CDJ68782.1 - 4.9 7.1 20.6 1.8 8.5 11.5 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.12 CDJ68782.1 - 8.5 5.0 6.6 12 4.6 4.6 1.2 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.11 CDJ68782.1 - 9 5.6 12.0 16 4.8 8.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 LigT_PEase PF02834.11 CDJ68783.1 - 0.04 13.8 0.2 0.14 12.1 0.1 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase Acetate_kinase PF00871.12 CDJ68785.1 - 1.1 7.7 6.0 1.3 7.5 4.2 1.0 1 0 0 1 1 1 0 Acetokinase family G-7-MTase PF12803.2 CDJ68785.1 - 1.2 8.2 9.0 1.6 7.7 6.2 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) ATP-gua_Ptrans PF00217.14 CDJ68785.1 - 2.3 7.4 11.3 0.97 8.7 6.4 1.4 1 1 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain V_ATPase_I PF01496.14 CDJ68785.1 - 3.2 5.4 19.2 3.6 5.3 13.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cpn60_TCP1 PF00118.19 CDJ68786.1 - 5.4e-119 397.9 2.3 6.4e-119 397.7 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GRDA PF04723.9 CDJ68786.1 - 0.7 9.5 4.6 0.88 9.2 0.5 2.4 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A TPR_11 PF13414.1 CDJ68787.1 - 6e-16 57.8 15.2 2.8e-05 23.6 0.0 5.0 1 1 5 6 6 6 6 TPR repeat TPR_2 PF07719.12 CDJ68787.1 - 2.2e-13 48.9 20.8 0.0042 16.8 0.5 7.0 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ68787.1 - 1.1e-11 44.8 15.7 0.00096 19.4 4.2 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ68787.1 - 6.1e-09 36.3 16.0 4e-06 27.3 6.7 5.1 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ68787.1 - 9.1e-09 35.1 24.2 0.00027 21.2 1.4 6.6 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ68787.1 - 1.7e-08 33.6 12.0 0.0081 15.7 0.2 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ68787.1 - 2.1e-08 33.9 16.6 2.8e-05 23.9 1.1 4.9 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ68787.1 - 2.1e-06 27.7 16.6 0.013 15.9 0.9 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ68787.1 - 4.6e-06 26.0 8.4 0.0022 17.6 0.3 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ68787.1 - 2e-05 24.4 3.5 0.016 15.3 0.1 5.2 3 2 3 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CDJ68787.1 - 2.9e-05 24.1 7.4 0.073 13.2 3.0 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CDJ68787.1 - 0.00023 20.7 9.3 0.25 11.2 0.1 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 CDJ68787.1 - 0.0022 17.7 0.7 0.48 10.2 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF3808 PF10300.4 CDJ68787.1 - 0.013 14.0 0.2 0.061 11.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) RPN7 PF10602.4 CDJ68787.1 - 0.058 12.7 0.1 2.5 7.4 0.0 2.8 3 0 0 3 3 3 0 26S proteasome subunit RPN7 NARP1 PF12569.3 CDJ68787.1 - 0.081 11.6 1.5 3.1 6.4 0.1 2.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 CDJ68787.1 - 0.087 12.7 11.8 1.1 9.3 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ68787.1 - 1.8 8.4 19.7 0.044 13.6 2.1 4.6 5 2 1 6 6 5 0 Tetratricopeptide repeat MSP1_C PF07462.6 CDJ68787.1 - 2.5 6.4 6.5 3.9 5.7 4.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CAF-1_p150 PF11600.3 CDJ68788.1 - 0.00056 19.3 32.0 0.00081 18.8 22.2 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDJ68788.1 - 0.48 9.7 45.7 0.64 9.3 31.7 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 CDJ68788.1 - 1.9 8.3 21.1 2.4 7.9 14.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 CDJ68788.1 - 5.7 6.8 23.8 7.8 6.3 16.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 CDJ68788.1 - 5.8 6.6 19.3 7.1 6.3 13.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.4 CDJ68788.1 - 5.9 4.9 41.7 6.9 4.7 28.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YcaO PF02624.11 CDJ68788.1 - 6.3 6.1 11.9 7.9 5.8 8.2 1.1 1 0 0 1 1 1 0 YcaO-like family CT47 PF15623.1 CDJ68788.1 - 8.5 6.0 25.1 11 5.6 17.4 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 TFIIA PF03153.8 CDJ68788.1 - 9.4 6.0 38.2 11 5.7 26.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MACPF PF01823.14 CDJ68790.1 - 0.13 11.8 2.4 0.13 11.8 1.7 1.1 1 0 0 1 1 1 0 MAC/Perforin domain Corona_nucleoca PF00937.13 CDJ68790.1 - 1.6 7.6 8.4 1.5 7.6 5.8 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1517 PF07466.6 CDJ68790.1 - 2.9 6.8 7.8 3.1 6.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Macoilin PF09726.4 CDJ68790.1 - 3 5.9 7.2 2.8 6.1 5.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF508 PF04370.7 CDJ68790.1 - 3.3 7.3 6.6 3.7 7.1 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Secretin_N_2 PF07655.8 CDJ68790.1 - 3.4 8.1 15.3 4.5 7.7 10.6 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Sporozoite_P67 PF05642.6 CDJ68790.1 - 4.9 4.8 7.5 4.9 4.9 5.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDK2AP PF09806.4 CDJ68790.1 - 6.6 6.9 8.5 8.2 6.6 5.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CAF-1_p150 PF11600.3 CDJ68790.1 - 7.2 5.9 8.8 8.5 5.6 6.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Apt1 PF10351.4 CDJ68790.1 - 8.1 5.1 6.7 9.4 4.9 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.4 CDJ68790.1 - 8.5 5.7 22.8 12 5.2 15.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDJ68791.1 - 3.1 7.1 4.7 3.7 6.9 3.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ENTH PF01417.15 CDJ68792.1 - 1.3e-27 96.1 0.0 2.5e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 ENTH domain SOBP PF15279.1 CDJ68792.1 - 4.8 7.4 34.3 0.24 11.7 4.3 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Glyco_hydro_9 PF00759.14 CDJ68793.1 - 0.0021 17.0 1.8 0.0027 16.6 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 APC_CDC26 PF10471.4 CDJ68793.1 - 0.088 13.5 20.8 0.22 12.2 4.9 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF506 PF04720.7 CDJ68793.1 - 0.096 12.3 2.5 0.12 11.9 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF506) PAT1 PF09770.4 CDJ68793.1 - 0.79 7.8 17.8 0.88 7.7 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4414 PF14377.1 CDJ68793.1 - 1.1 9.2 13.1 1.9 8.4 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) DUF3371 PF11851.3 CDJ68793.1 - 2.6 8.7 15.3 4.2 8.0 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) LcrG PF07216.7 CDJ68793.1 - 2.7 8.0 10.5 0.45 10.5 0.4 2.2 2 0 0 2 2 2 0 LcrG protein Activator_LAG-3 PF11498.3 CDJ68793.1 - 3.3 6.3 34.9 0.72 8.5 6.7 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Seryl_tRNA_N PF02403.17 CDJ68794.1 - 0.19 11.7 9.4 0.63 10.0 1.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ARA70 PF12489.3 CDJ68794.1 - 8.7 6.3 13.9 2.7 7.9 1.5 2.3 2 0 0 2 2 2 0 Nuclear coactivator FimP PF09766.4 CDJ68795.1 - 0.0032 16.5 17.0 0.0033 16.5 11.8 1.1 1 0 0 1 1 1 1 Fms-interacting protein BLVR PF06375.6 CDJ68795.1 - 0.0075 16.0 4.9 0.008 16.0 3.4 1.1 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) DUF1754 PF08555.5 CDJ68795.1 - 0.0098 16.4 9.7 0.014 16.0 6.7 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) NARP1 PF12569.3 CDJ68795.1 - 0.057 12.1 15.3 0.066 11.9 10.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAM176 PF14851.1 CDJ68795.1 - 0.082 12.5 3.3 0.12 12.0 2.3 1.2 1 0 0 1 1 1 0 FAM176 family Activator_LAG-3 PF11498.3 CDJ68795.1 - 0.12 11.0 37.9 0.13 10.9 26.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CDJ68795.1 - 0.13 12.0 17.6 0.13 11.9 12.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Claudin_2 PF13903.1 CDJ68795.1 - 0.19 11.3 10.5 0.54 9.9 7.3 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction XRCC4 PF06632.7 CDJ68795.1 - 0.33 9.7 9.4 0.37 9.5 6.5 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SpoVR PF04293.8 CDJ68795.1 - 0.34 9.2 7.6 0.34 9.2 5.3 1.1 1 0 0 1 1 1 0 SpoVR like protein eIF-3_zeta PF05091.7 CDJ68795.1 - 0.35 9.4 12.9 0.36 9.4 8.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Glt_symporter PF03616.9 CDJ68795.1 - 0.45 8.9 3.1 0.46 8.9 2.1 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter AUX_IAA PF02309.11 CDJ68795.1 - 0.57 9.8 11.3 0.65 9.7 7.8 1.2 1 0 0 1 1 1 0 AUX/IAA family FLO_LFY PF01698.11 CDJ68795.1 - 0.62 8.8 14.8 0.67 8.7 10.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Maf1 PF09174.5 CDJ68795.1 - 0.64 9.8 4.7 0.68 9.7 3.3 1.2 1 0 0 1 1 1 0 Maf1 regulator Peptidase_S49_N PF08496.5 CDJ68795.1 - 0.69 9.6 12.6 0.84 9.4 8.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-DHHC PF01529.15 CDJ68795.1 - 0.71 9.2 5.3 0.87 8.9 3.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Endonuc_Holl PF10107.4 CDJ68795.1 - 0.71 9.5 8.9 0.95 9.1 6.2 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Peptidase_U57 PF05582.7 CDJ68795.1 - 0.75 8.7 6.8 0.86 8.5 4.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 FHIPEP PF00771.15 CDJ68795.1 - 0.81 7.9 6.7 0.95 7.7 4.6 1.2 1 0 0 1 1 1 0 FHIPEP family PAT1 PF09770.4 CDJ68795.1 - 0.93 7.6 33.3 1 7.5 23.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2215 PF10225.4 CDJ68795.1 - 0.94 8.8 5.4 1 8.7 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Folate_carrier PF01770.13 CDJ68795.1 - 1 7.7 8.4 1.4 7.3 5.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier FAM217 PF15344.1 CDJ68795.1 - 1.1 8.8 16.6 1.3 8.4 11.5 1.1 1 0 0 1 1 1 0 FAM217 family TMEM247 PF15444.1 CDJ68795.1 - 1.1 9.0 8.6 1.2 8.9 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 eIF_4EBP PF05456.6 CDJ68795.1 - 1.1 8.9 9.7 1.8 8.2 6.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Serinc PF03348.10 CDJ68795.1 - 1.1 7.8 11.3 1.2 7.7 7.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2126 PF09899.4 CDJ68795.1 - 1.2 7.1 8.7 1.2 7.0 6.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Band_3_cyto PF07565.8 CDJ68795.1 - 1.4 8.3 13.4 1.6 8.1 9.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gag_spuma PF03276.9 CDJ68795.1 - 1.5 7.0 26.8 1.9 6.7 18.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DDHD PF02862.12 CDJ68795.1 - 1.5 8.5 13.6 1.7 8.3 9.4 1.1 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 CDJ68795.1 - 1.6 8.4 8.7 1.8 8.2 6.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Inhibitor_I71 PF12628.2 CDJ68795.1 - 1.7 8.2 6.8 2.2 7.9 4.7 1.2 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Hid1 PF12722.2 CDJ68795.1 - 1.7 6.1 12.2 1.8 6.1 8.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Baculo_PP31 PF05311.6 CDJ68795.1 - 2 7.5 11.8 2.1 7.5 8.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Ribonuclease_3 PF00636.21 CDJ68795.1 - 2.1 8.8 5.3 2.7 8.4 3.7 1.1 1 0 0 1 1 1 0 Ribonuclease III domain DDRGK PF09756.4 CDJ68795.1 - 2.4 7.5 17.6 3.2 7.1 12.2 1.2 1 0 0 1 1 1 0 DDRGK domain Paf1 PF03985.8 CDJ68795.1 - 2.5 6.7 14.5 2.8 6.5 10.1 1.1 1 0 0 1 1 1 0 Paf1 CDK5_activator PF03261.10 CDJ68795.1 - 2.5 7.3 12.9 2.7 7.2 9.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Neur_chan_memb PF02932.11 CDJ68795.1 - 2.5 7.9 7.7 2.7 7.8 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PBP1_TM PF14812.1 CDJ68795.1 - 2.6 8.4 5.4 3.9 7.8 3.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S15 PF02129.13 CDJ68795.1 - 3.2 7.0 13.0 4 6.7 9.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GAGA_bind PF06217.7 CDJ68795.1 - 3.3 7.6 13.5 3.6 7.4 9.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2149 PF09919.4 CDJ68795.1 - 3.9 7.6 7.1 6.1 6.9 4.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) YjgP_YjgQ PF03739.9 CDJ68795.1 - 5 5.7 6.0 5.3 5.6 4.1 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family LIM_bind PF01803.11 CDJ68795.1 - 5.1 6.1 15.7 6.4 5.8 10.9 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Sec62 PF03839.11 CDJ68795.1 - 5.1 6.4 7.1 5.2 6.4 4.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Glyco_transf_15 PF01793.11 CDJ68795.1 - 5.4 5.8 11.2 6.9 5.5 7.8 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Plasmodium_Vir PF05795.6 CDJ68795.1 - 5.6 6.0 5.7 5.7 6.0 4.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ycf1 PF05758.7 CDJ68795.1 - 5.8 4.4 11.6 6.1 4.4 8.0 1.0 1 0 0 1 1 1 0 Ycf1 UPF0560 PF10577.4 CDJ68795.1 - 6.4 4.8 20.1 6.8 4.8 13.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RR_TM4-6 PF06459.7 CDJ68795.1 - 6.5 6.5 15.5 8 6.2 10.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 CDJ68795.1 - 7 6.9 15.1 7.7 6.7 10.5 1.1 1 0 0 1 1 1 0 AAA domain Bud13 PF09736.4 CDJ68795.1 - 7.1 6.8 18.1 10 6.3 12.5 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Pex16 PF08610.5 CDJ68795.1 - 7.2 5.4 11.2 8.5 5.2 7.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4207 PF13904.1 CDJ68795.1 - 7.2 5.8 29.2 8.4 5.6 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) PBP_sp32 PF07222.7 CDJ68795.1 - 7.6 5.6 19.8 8.7 5.4 13.7 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1980 PF09323.5 CDJ68795.1 - 7.9 6.1 13.5 11 5.7 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) V_ATPase_I PF01496.14 CDJ68796.1 - 6.5e-110 368.1 3.7 1.4e-109 367.1 2.6 1.5 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2201_N PF13203.1 CDJ68796.1 - 0.00089 18.5 1.4 0.0012 18.1 1.0 1.2 1 0 0 1 1 1 1 Putative metallopeptidase domain DUF1510 PF07423.6 CDJ68796.1 - 0.038 13.3 0.3 0.038 13.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1183 PF06682.7 CDJ68796.1 - 0.059 12.9 0.5 0.091 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) TFIIA PF03153.8 CDJ68796.1 - 0.21 11.4 11.6 0.29 10.9 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF788 PF05620.6 CDJ68796.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF788) V_ATPase_I PF01496.14 CDJ68798.1 - 8.7e-21 73.4 0.0 1.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family AAA_19 PF13245.1 CDJ68798.1 - 0.039 13.6 2.4 0.067 12.9 0.3 2.4 2 1 0 2 2 2 0 Part of AAA domain EFG_C PF00679.19 CDJ68798.1 - 0.11 12.4 0.0 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G C-terminus zf-C3HC4_3 PF13920.1 CDJ68799.1 - 0.00021 20.8 13.0 0.00048 19.7 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SR-25 PF10500.4 CDJ68799.1 - 0.00049 19.6 5.8 0.00049 19.6 4.0 2.6 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein zf-C3HC4_2 PF13923.1 CDJ68799.1 - 0.0041 17.1 15.7 0.0041 17.1 10.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ68799.1 - 0.0086 15.7 16.3 0.027 14.1 11.3 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDJ68799.1 - 0.0093 15.7 17.9 0.01 15.6 11.5 1.7 2 0 0 2 2 2 1 Ring finger domain DWNN PF08783.6 CDJ68799.1 - 0.098 12.6 0.0 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 DWNN domain zf-C3HC4 PF00097.20 CDJ68799.1 - 0.11 12.2 15.9 0.28 10.8 11.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CDJ68799.1 - 0.2 11.4 5.3 0.38 10.5 3.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF393 PF04134.7 CDJ68799.1 - 0.32 12.1 0.1 0.32 12.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF393 zf-C3HC4_4 PF15227.1 CDJ68799.1 - 0.65 9.9 14.3 2.8 7.9 9.9 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CDJ68799.1 - 3.6 7.7 11.4 7.3 6.7 7.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Peptidase_S8 PF00082.17 CDJ68800.1 - 1.6e-17 63.6 35.0 1.6e-17 63.6 24.3 3.3 3 1 0 3 3 3 1 Subtilase family Fis1_TPR_C PF14853.1 CDJ68800.1 - 0.047 13.5 2.5 0.052 13.4 0.0 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat GYF PF02213.11 CDJ68802.1 - 8.6e-06 25.2 0.1 1.8e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 GYF domain AFG1_ATPase PF03969.11 CDJ68803.1 - 4.1e-72 242.9 0.0 1.1e-69 235.0 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.13 CDJ68803.1 - 0.00017 21.2 0.1 0.00034 20.3 0.0 1.5 1 1 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.7 CDJ68803.1 - 0.01 15.4 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 CDJ68803.1 - 0.014 15.3 0.0 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CDJ68803.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDJ68803.1 - 0.078 12.7 0.9 0.42 10.3 0.0 2.4 2 1 1 3 3 3 0 Part of AAA domain Cullin PF00888.17 CDJ68804.1 - 6.2e-31 107.5 0.0 1.8e-26 92.8 0.0 2.1 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 CDJ68804.1 - 8.8e-14 51.0 0.1 2.2e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain SR-25 PF10500.4 CDJ68804.1 - 0.24 10.8 12.5 0.37 10.2 8.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1517 PF07466.6 CDJ68805.1 - 0.0019 17.2 0.6 0.0019 17.2 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) EphA2_TM PF14575.1 CDJ68805.1 - 0.12 12.8 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MR_MLE_C PF13378.1 CDJ68805.1 - 1.8 8.5 13.5 9.8 6.1 7.6 2.4 2 0 0 2 2 2 0 Enolase C-terminal domain-like GPCR_chapero_1 PF11904.3 CDJ68806.1 - 0.95 8.5 14.1 1.4 7.9 9.8 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF4647 PF15504.1 CDJ68806.1 - 3 6.6 26.0 4 6.1 18.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Peptidase_S64 PF08192.6 CDJ68806.1 - 5.4 5.2 27.4 6.2 5.0 19.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 CDJ68806.1 - 6.9 4.8 28.0 8.6 4.5 19.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 CDJ68806.1 - 8.8 5.4 28.7 11 5.1 19.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF966 PF06136.8 CDJ68806.1 - 9.1 5.5 27.9 15 4.8 19.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PHD PF00628.24 CDJ68807.1 - 0.00015 21.3 3.1 0.00015 21.3 2.2 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CDJ68807.1 - 0.00033 19.9 4.4 0.00033 19.9 3.0 2.1 2 0 0 2 2 2 1 PHD-finger Pol_alpha_B_N PF08418.5 CDJ68808.1 - 0.15 11.5 14.1 0.2 11.1 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TAF1D PF15333.1 CDJ68808.1 - 0.42 10.3 7.8 0.58 9.8 5.4 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Myco_19_kDa PF05481.7 CDJ68808.1 - 0.44 10.3 3.3 0.51 10.1 2.3 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen SR-25 PF10500.4 CDJ68808.1 - 0.45 9.9 31.4 1.1 8.6 21.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDK5_activator PF03261.10 CDJ68808.1 - 0.46 9.7 9.9 0.54 9.5 6.8 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SprA-related PF12118.3 CDJ68808.1 - 0.53 9.5 29.9 0.79 9.0 20.7 1.2 1 0 0 1 1 1 0 SprA-related family Apt1 PF10351.4 CDJ68808.1 - 0.55 9.0 11.2 0.64 8.8 7.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Raftlin PF15250.1 CDJ68808.1 - 0.81 8.1 10.4 0.95 7.9 7.2 1.0 1 0 0 1 1 1 0 Raftlin Corona_nucleoca PF00937.13 CDJ68808.1 - 0.92 8.3 20.9 1.1 8.0 14.5 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CAF-1_p150 PF11600.3 CDJ68808.1 - 1.1 8.6 21.3 1.4 8.2 14.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3474 PF11960.3 CDJ68808.1 - 1.1 9.2 4.4 1.6 8.7 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF572 PF04502.8 CDJ68808.1 - 1.2 8.2 12.4 1.4 8.0 8.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AUX_IAA PF02309.11 CDJ68808.1 - 1.5 8.4 10.0 2.3 7.9 6.9 1.2 1 0 0 1 1 1 0 AUX/IAA family RR_TM4-6 PF06459.7 CDJ68808.1 - 1.7 8.4 6.4 2.3 8.0 4.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 CDJ68808.1 - 1.9 8.7 9.2 2.3 8.4 6.4 1.1 1 0 0 1 1 1 0 AAA domain DUF4207 PF13904.1 CDJ68808.1 - 2.3 7.4 27.6 3.2 7.0 19.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF605 PF04652.11 CDJ68808.1 - 2.4 7.4 21.9 3 7.1 15.2 1.1 1 0 0 1 1 1 0 Vta1 like SASRP1 PF15160.1 CDJ68808.1 - 2.9 7.0 5.6 3.5 6.7 3.8 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Senescence_reg PF04520.8 CDJ68808.1 - 5.1 7.5 14.3 6.7 7.1 9.9 1.1 1 0 0 1 1 1 0 Senescence regulator PAT1 PF09770.4 CDJ68808.1 - 5.5 5.0 32.5 6.8 4.8 22.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FLO_LFY PF01698.11 CDJ68808.1 - 5.9 5.6 10.0 6.5 5.4 6.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1675 PF07897.6 CDJ68808.1 - 6.1 6.6 15.5 7.5 6.3 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) NCD2 PF04905.8 CDJ68808.1 - 6.9 6.4 8.4 8.6 6.1 5.8 1.1 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Med15 PF09606.5 CDJ68808.1 - 8.1 4.5 42.1 9.5 4.2 29.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3801 PF12687.2 CDJ68808.1 - 9.2 5.7 13.9 18 4.8 9.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) Trypan_PARP PF05887.6 CDJ68809.1 - 8.2 6.2 11.5 8.3 6.2 7.4 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Med15 PF09606.5 CDJ68812.1 - 0.038 12.2 26.7 0.053 11.7 18.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3736 PF12540.3 CDJ68812.1 - 0.043 14.0 6.9 0.048 13.8 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) DUF2910 PF11139.3 CDJ68812.1 - 0.063 12.4 13.1 0.075 12.1 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Spt20 PF12090.3 CDJ68812.1 - 0.16 11.2 3.6 0.17 11.2 2.5 1.2 1 0 0 1 1 1 0 Spt20 family Draxin PF15550.1 CDJ68812.1 - 0.46 10.0 5.3 0.5 9.9 3.6 1.1 1 0 0 1 1 1 0 Draxin DUF3464 PF11947.3 CDJ68812.1 - 0.68 9.3 5.6 0.88 9.0 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) MSP1_C PF07462.6 CDJ68812.1 - 2.2 6.5 16.1 2.2 6.5 11.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus WES_acyltransf PF03007.11 CDJ68812.1 - 2.3 7.7 13.1 2.8 7.4 9.1 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain LCD1 PF09798.4 CDJ68812.1 - 2.3 6.0 5.8 2.5 6.0 4.0 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein PAT1 PF09770.4 CDJ68812.1 - 3.5 5.7 17.7 4.1 5.5 12.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M20 PF01546.23 CDJ68813.1 - 0.076 12.5 1.2 0.084 12.3 0.0 1.7 2 1 0 2 2 2 0 Peptidase family M20/M25/M40 PAT1 PF09770.4 CDJ68813.1 - 0.2 9.8 100.7 0.49 8.5 37.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDJ68813.1 - 6.3 4.8 43.8 2 6.4 15.6 2.0 2 0 0 2 2 2 0 Utp14 protein SOBP PF15279.1 CDJ68813.1 - 7 6.9 54.6 1.3 9.3 16.1 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein NOGCT PF08155.6 CDJ68814.1 - 1.3e-25 88.8 2.9 1.3e-25 88.8 2.0 2.7 2 0 0 2 2 2 1 NOGCT (NUC087) domain DUF2937 PF11157.3 CDJ68814.1 - 0.086 12.1 2.9 0.16 11.2 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) GDA1_CD39 PF01150.12 CDJ68815.1 - 2.9e-27 95.2 5.8 1.5e-19 69.8 0.0 3.2 3 0 0 3 3 3 2 GDA1/CD39 (nucleoside phosphatase) family MIP-T3 PF10243.4 CDJ68815.1 - 8e-08 31.2 1.6 8e-08 31.2 1.1 2.6 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 SprA-related PF12118.3 CDJ68815.1 - 9.6e-06 25.1 47.7 0.0016 17.8 12.9 3.2 3 0 0 3 3 3 2 SprA-related family SR-25 PF10500.4 CDJ68815.1 - 0.0051 16.3 16.5 0.0051 16.3 11.4 5.6 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein Collagen PF01391.13 CDJ68815.1 - 0.018 14.5 29.4 0.059 12.9 20.3 1.9 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) TFIIA PF03153.8 CDJ68815.1 - 3 7.6 28.5 0.92 9.3 5.1 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit U1snRNP70_N PF12220.3 CDJ68815.1 - 3.9 7.8 19.5 0.076 13.3 3.6 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HMG_CoA_synt_C PF08540.5 CDJ68817.1 - 0.085 12.3 0.2 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Ribosomal_60s PF00428.14 CDJ68819.1 - 0.0071 16.7 12.1 0.013 15.8 8.4 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2360 PF10152.4 CDJ68819.1 - 0.21 11.8 5.2 0.27 11.5 3.6 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1180 PF06679.7 CDJ68819.1 - 2.1 8.2 7.2 2.6 7.9 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CAF-1_p150 PF11600.3 CDJ68821.1 - 6.8 6.0 44.3 7.1 5.9 30.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_C48 PF02902.14 CDJ68822.1 - 3.7e-11 43.0 0.0 1.6e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_M17 PF00883.16 CDJ68823.1 - 7.2e-119 396.2 0.0 9.6e-119 395.8 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CDJ68823.1 - 7.4e-12 45.1 2.6 8.3e-12 44.9 0.1 2.3 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain SSP160 PF06933.6 CDJ68826.1 - 0.012 13.6 35.4 0.0069 14.4 9.0 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 CDJ68826.1 - 0.11 12.2 54.4 0.3 10.8 12.5 2.4 3 0 0 3 3 3 0 Mucin-like glycoprotein RabGAP-TBC PF00566.13 CDJ68827.1 - 2.8e-33 115.1 0.3 2.5e-17 63.0 0.0 3.1 2 1 0 2 2 2 2 Rab-GTPase-TBC domain SlyX PF04102.7 CDJ68827.1 - 0.0052 17.1 2.0 0.29 11.5 0.3 3.0 2 0 0 2 2 2 1 SlyX Peptidase_C48 PF02902.14 CDJ68828.1 - 0.00027 20.6 0.0 0.0028 17.3 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Herpes_gE PF02480.11 CDJ68828.1 - 0.0071 14.6 0.0 0.0071 14.6 0.0 2.1 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF1510 PF07423.6 CDJ68828.1 - 0.23 10.8 3.2 0.5 9.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) PAT1 PF09770.4 CDJ68832.1 - 3.2 5.8 18.3 3.9 5.5 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ68833.1 - 8.2 6.6 15.7 2.2 8.5 1.4 2.5 2 0 0 2 2 2 0 AAA domain Flavokinase PF01687.12 CDJ68836.1 - 3.4e-08 33.3 0.0 1.3e-06 28.2 0.0 2.7 2 1 0 2 2 2 1 Riboflavin kinase Herpes_UL87 PF03043.9 CDJ68836.1 - 0.3 9.4 5.9 0.61 8.3 4.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL87 family Rxt3 PF08642.5 CDJ68836.1 - 5.6 7.2 6.2 1.3 9.3 0.6 2.7 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 Pkinase PF00069.20 CDJ68837.1 - 4.9e-28 97.9 6.6 2.4e-15 56.3 0.0 3.7 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68837.1 - 3.5e-09 36.1 2.1 4.9e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Collagen PF01391.13 CDJ68837.1 - 0.0055 16.2 13.0 0.0096 15.4 9.0 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Med15 PF09606.5 CDJ68837.1 - 0.08 11.1 94.0 0.056 11.6 60.4 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Methyltransf_16 PF10294.4 CDJ68839.1 - 1.2e-05 24.8 0.1 0.013 14.9 0.2 3.2 2 1 0 2 2 2 2 Putative methyltransferase FimP PF09766.4 CDJ68841.1 - 0.59 9.1 5.0 0.8 8.7 3.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4175 PF13779.1 CDJ68841.1 - 5.9 4.4 19.7 8.3 3.9 13.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SR-25 PF10500.4 CDJ68842.1 - 0.00099 18.6 9.7 0.00099 18.6 6.7 6.3 4 1 2 6 6 6 2 Nuclear RNA-splicing-associated protein FlxA PF14282.1 CDJ68842.1 - 0.0064 16.4 24.5 0.0064 16.4 17.0 6.4 6 0 0 6 6 6 2 FlxA-like protein Activator_LAG-3 PF11498.3 CDJ68842.1 - 0.26 9.9 42.1 1.2 7.7 5.1 2.7 2 0 0 2 2 2 0 Transcriptional activator LAG-3 FimP PF09766.4 CDJ68842.1 - 0.72 8.8 29.3 0.21 10.6 8.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein PAT1 PF09770.4 CDJ68842.1 - 3.2 5.8 39.6 6.2 4.9 27.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-DHHC PF01529.15 CDJ68842.1 - 3.4 7.0 4.2 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase AP2 PF00847.15 CDJ68844.1 - 5.1e-08 32.9 0.5 5.1e-08 32.9 0.3 3.1 3 0 0 3 3 3 1 AP2 domain MtN3_slv PF03083.11 CDJ68845.1 - 3.3e-35 119.8 3.8 7.1e-20 70.6 0.2 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Methyltransf_26 PF13659.1 CDJ68846.1 - 0.07 13.1 5.3 0.17 11.9 3.6 1.7 1 1 0 1 1 1 0 Methyltransferase domain SAE2 PF08573.5 CDJ68848.1 - 3.9e-09 37.0 0.1 3.9e-09 37.0 0.1 4.0 4 1 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Glyco_hydro_16 PF00722.16 CDJ68849.1 - 5.6e-06 25.7 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAN_4 PF14295.1 CDJ68849.1 - 0.00091 18.8 0.4 0.0038 16.9 0.2 2.0 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 CDJ68849.1 - 0.012 15.2 2.4 0.012 15.2 1.6 2.1 2 0 0 2 2 2 0 PAN domain Pkinase PF00069.20 CDJ68851.1 - 6.7e-61 205.7 0.1 2.2e-60 203.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ68851.1 - 1.8e-37 128.8 0.5 2.5e-37 128.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ68851.1 - 4.2e-15 55.4 0.0 7.8e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDJ68851.1 - 3.5e-06 26.2 0.0 5.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDJ68851.1 - 2.6e-05 24.0 0.1 2.6e-05 24.0 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDJ68851.1 - 0.014 15.0 0.8 0.022 14.3 0.0 1.7 2 1 0 2 2 2 0 Choline/ethanolamine kinase Suf PF05843.9 CDJ68851.1 - 7.6 6.1 15.0 12 5.5 10.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ68851.1 - 8.3 6.1 22.4 11 5.8 15.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CDJ68851.1 - 8.7 5.6 33.4 12 5.2 23.1 1.1 1 0 0 1 1 1 0 Vta1 like MaoC_dehydrat_N PF13452.1 CDJ68852.1 - 0.019 14.7 1.6 0.053 13.3 1.1 1.8 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Borrelia_P83 PF05262.6 CDJ68852.1 - 0.081 11.1 25.4 0.13 10.4 17.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.7 CDJ68852.1 - 0.48 10.2 29.7 0.23 11.3 14.9 2.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF342 PF03961.8 CDJ68852.1 - 0.67 8.3 15.8 1.2 7.4 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LMBR1 PF04791.11 CDJ68852.1 - 0.77 8.2 11.2 1.4 7.3 7.8 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Ycf1 PF05758.7 CDJ68852.1 - 2.5 5.7 25.3 4.3 4.9 17.5 1.3 1 0 0 1 1 1 0 Ycf1 HlyD_2 PF12700.2 CDJ68852.1 - 4 6.4 25.8 7 5.7 17.9 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Hom_end_hint PF05203.11 CDJ68852.1 - 9.9 5.8 14.9 20 4.8 10.3 1.5 1 0 0 1 1 1 0 Hom_end-associated Hint ORC3_N PF07034.6 CDJ68853.1 - 5.8e-12 45.2 9.1 7.2e-11 41.6 0.1 4.1 4 1 0 4 4 4 2 Origin recognition complex (ORC) subunit 3 N-terminus EGF_CA PF07645.10 CDJ68854.1 - 2.5e-24 84.9 67.4 5.5e-11 42.2 6.3 4.7 5 0 0 5 5 5 4 Calcium-binding EGF domain EGF_3 PF12947.2 CDJ68854.1 - 2.4e-10 40.1 62.6 6.1e-05 22.9 6.6 5.1 5 0 0 5 5 5 4 EGF domain cEGF PF12662.2 CDJ68854.1 - 1.5e-09 37.3 27.0 0.0087 15.6 0.2 5.7 5 1 0 5 5 5 4 Complement Clr-like EGF-like EGF PF00008.22 CDJ68854.1 - 3.9e-05 23.5 48.7 0.021 14.7 3.7 5.2 5 0 0 5 5 5 4 EGF-like domain FXa_inhibition PF14670.1 CDJ68854.1 - 6.5e-05 22.9 55.7 0.023 14.7 1.9 4.8 4 1 0 4 4 4 4 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CDJ68854.1 - 0.0013 18.4 22.8 0.0061 16.3 7.3 4.2 4 1 0 4 4 4 2 MSP1 EGF domain 1 hEGF PF12661.2 CDJ68854.1 - 0.0053 16.7 7.3 0.73 10.0 0.3 4.6 3 0 0 3 3 3 2 Human growth factor-like EGF DUF348 PF03990.9 CDJ68854.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF348) NPP PF08384.5 CDJ68854.1 - 1.2 8.8 0.0 1.2 8.8 0.0 4.2 4 0 0 4 4 4 0 Pro-opiomelanocortin, N-terminal region 14-3-3 PF00244.15 CDJ68855.1 - 1.4e-108 361.3 9.6 1.8e-108 361.0 6.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 CDJ68855.1 - 0.73 9.1 5.6 0.11 11.9 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) RVT_1 PF00078.22 CDJ68856.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1754 PF08555.5 CDJ68857.1 - 2.7e-06 27.8 9.5 0.0012 19.3 6.6 2.4 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) HTH_32 PF13565.1 CDJ68857.1 - 0.0039 17.9 1.5 0.0039 17.9 1.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain SelP_C PF04593.9 CDJ68857.1 - 0.06 13.1 0.6 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, C terminal region IMD PF08397.6 CDJ68858.1 - 0.022 14.0 11.3 0.28 10.4 5.5 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain DASH_Duo1 PF08651.5 CDJ68858.1 - 0.063 12.8 1.2 2.8 7.5 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Duo1 MxiH PF09392.5 CDJ68858.1 - 0.28 11.7 5.2 8.4 7.0 3.6 2.9 1 1 0 1 1 1 0 Type III secretion needle MxiH like L31 PF09784.4 CDJ68858.1 - 0.38 10.8 0.0 0.38 10.8 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 CDC37_N PF03234.9 CDJ68858.1 - 0.87 9.8 9.8 0.28 11.4 2.7 2.3 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding APG6 PF04111.7 CDJ68858.1 - 3.7 6.4 11.0 30 3.5 7.7 2.1 1 1 0 1 1 1 0 Autophagy protein Apg6 Herpes_DNAp_acc PF04929.7 CDJ68859.1 - 0.81 8.5 7.4 0.96 8.3 5.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.8 CDJ68859.1 - 2.4 7.9 10.0 2.5 7.9 7.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CDJ68859.1 - 2.8 6.1 12.2 3.2 5.9 8.5 1.0 1 0 0 1 1 1 0 Transmembrane protein TMEM51 PF15345.1 CDJ68859.1 - 3.3 7.3 9.1 3.8 7.1 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 SpoIIIAH PF12685.2 CDJ68859.1 - 3.4 7.1 7.6 4.1 6.8 5.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Apt1 PF10351.4 CDJ68859.1 - 4.2 6.1 8.0 4.6 5.9 5.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.12 CDJ68859.1 - 4.5 7.0 7.9 5.3 6.7 5.4 1.1 1 0 0 1 1 1 0 DDHD domain SRP-alpha_N PF04086.8 CDJ68859.1 - 7.5 5.8 10.9 9 5.5 7.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Bax1-I PF01027.15 CDJ68860.1 - 3.4e-26 92.1 24.0 4e-26 91.9 16.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PIG-Y PF15159.1 CDJ68861.1 - 8.9e-05 22.6 3.7 8.9e-05 22.6 2.6 1.6 2 0 0 2 2 2 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Med15 PF09606.5 CDJ68861.1 - 0.0066 14.7 17.0 0.0085 14.3 11.8 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF966 PF06136.8 CDJ68861.1 - 0.023 14.1 0.5 0.025 13.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MSP1_C PF07462.6 CDJ68861.1 - 0.2 9.9 6.9 0.24 9.7 4.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus LCD1 PF09798.4 CDJ68861.1 - 0.53 8.2 5.1 0.6 8.0 3.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3040 PF11239.3 CDJ68861.1 - 0.62 10.1 8.2 1.5 8.9 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Senescence_reg PF04520.8 CDJ68861.1 - 0.93 9.9 5.8 1.4 9.3 4.0 1.3 1 0 0 1 1 1 0 Senescence regulator DUF677 PF05055.7 CDJ68861.1 - 6.6 5.3 6.0 0.35 9.4 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DivIC PF04977.10 CDJ68861.1 - 8.2 5.9 11.8 17 4.9 8.1 1.5 1 0 0 1 1 1 0 Septum formation initiator BLVR PF06375.6 CDJ68862.1 - 0.0019 18.0 9.1 0.0019 18.0 6.3 3.0 2 1 1 3 3 3 1 Bovine leukaemia virus receptor (BLVR) Neur_chan_memb PF02932.11 CDJ68862.1 - 2.6 7.8 14.2 8 6.2 6.4 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TFIIF_alpha PF05793.7 CDJ68862.1 - 5.8 5.1 38.2 0.06 11.7 3.6 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_UL87 PF03043.9 CDJ68863.1 - 0.018 13.4 1.3 0.023 13.0 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Med15 PF09606.5 CDJ68863.1 - 0.57 8.3 31.7 0.4 8.8 2.8 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Senescence_reg PF04520.8 CDJ68863.1 - 5.6 7.4 15.2 4.7 7.6 7.9 2.1 2 0 0 2 2 2 0 Senescence regulator BTV_NS2 PF04514.7 CDJ68863.1 - 6.1 5.6 17.8 11 4.7 12.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ribosomal_L18e PF00828.14 CDJ68864.1 - 3.1e-33 114.8 0.1 3.8e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 SR-25 PF10500.4 CDJ68867.1 - 0.00088 18.8 4.3 0.00088 18.8 3.0 3.9 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein Tautomerase_2 PF14552.1 CDJ68867.1 - 0.54 10.3 2.0 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 Tautomerase enzyme Utp14 PF04615.8 CDJ68867.1 - 0.55 8.3 19.6 0.72 7.9 13.6 1.2 1 0 0 1 1 1 0 Utp14 protein DUF4504 PF14953.1 CDJ68867.1 - 0.58 9.3 9.0 0.16 11.2 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4504) DUF572 PF04502.8 CDJ68867.1 - 3 6.9 24.5 3.8 6.6 12.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) AT_hook PF02178.14 CDJ68868.1 - 5.4 7.0 12.9 0.26 11.0 3.6 3.1 2 0 0 2 2 2 0 AT hook motif His_Phos_2 PF00328.17 CDJ68869.1 - 0.54 9.5 13.3 1e+02 2.0 9.2 2.1 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) PIH1 PF08190.7 CDJ68869.1 - 1.6 8.1 9.1 1.8 7.8 6.3 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DNA_pol_viral_N PF00242.12 CDJ68869.1 - 5.4 5.9 13.9 6.9 5.5 9.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Presenilin PF01080.12 CDJ68869.1 - 9.7 4.8 10.8 13 4.4 7.5 1.3 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.4 CDJ68870.1 - 0.031 14.1 8.6 0.039 13.8 5.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Blt1 PF12754.2 CDJ68870.1 - 0.47 9.9 3.0 0.92 9.0 2.1 1.4 1 1 0 1 1 1 0 Cell-cycle control medial ring component YscJ_FliF_C PF08345.6 CDJ68870.1 - 0.92 9.4 7.8 0.21 11.5 1.6 2.0 1 1 1 2 2 2 0 Flagellar M-ring protein C-terminal DUF605 PF04652.11 CDJ68875.1 - 0.011 15.1 27.3 0.017 14.5 18.9 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CDJ68875.1 - 0.018 13.3 36.4 0.024 12.9 25.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GET2 PF08690.5 CDJ68875.1 - 0.035 13.3 19.1 0.048 12.8 13.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SWIM PF04434.12 CDJ68875.1 - 0.14 11.6 0.0 0.14 11.6 0.0 2.7 2 0 0 2 2 2 0 SWIM zinc finger Suc_Fer-like PF06999.7 CDJ68875.1 - 0.29 11.1 8.4 1.5 8.7 5.2 2.1 2 0 0 2 2 2 0 Sucrase/ferredoxin-like RAP1 PF07218.6 CDJ68875.1 - 0.56 8.2 18.7 0.75 7.8 13.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) eIF-3_zeta PF05091.7 CDJ68875.1 - 0.83 8.1 23.7 1.1 7.7 16.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Macoilin PF09726.4 CDJ68875.1 - 1.2 7.3 40.2 1.7 6.8 27.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Med15 PF09606.5 CDJ68877.1 - 0.027 12.6 122.8 0.035 12.3 85.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ68877.1 - 0.031 12.5 96.0 0.032 12.4 66.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bac_luciferase PF00296.15 CDJ68877.1 - 6.1 5.8 14.1 1.9e+02 0.9 9.7 2.3 1 1 0 1 1 1 0 Luciferase-like monooxygenase Ribosomal_60s PF00428.14 CDJ68878.1 - 0.019 15.3 6.8 0.019 15.3 4.7 2.5 2 1 0 2 2 2 0 60s Acidic ribosomal protein GTP_EFTU PF00009.22 CDJ68880.1 - 1.1e-40 139.0 0.0 6.1e-40 136.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CDJ68880.1 - 7.6e-05 22.4 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CDJ68880.1 - 0.0063 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CDJ68880.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G C-terminus YIF1 PF03878.10 CDJ68881.1 - 7.5e-29 100.5 0.6 7.5e-29 100.5 0.4 1.4 2 0 0 2 2 2 1 YIF1 PCI PF01399.22 CDJ68882.1 - 4.9e-14 52.5 0.1 9.8e-12 45.1 0.0 2.4 2 0 0 2 2 2 2 PCI domain LCCL PF03815.14 CDJ68883.1 - 2.6e-21 75.3 0.1 8.4e-21 73.7 0.1 1.9 1 0 0 1 1 1 1 LCCL domain tRNA-synt_His PF13393.1 CDJ68884.1 - 0.068 12.2 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase PMEI PF04043.10 CDJ68884.1 - 0.087 12.7 1.0 0.15 11.9 0.7 1.3 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF3626 PF12294.3 CDJ68885.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) TPR_11 PF13414.1 CDJ68886.1 - 1e-09 37.8 0.4 1.4e-07 31.0 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CDJ68886.1 - 0.00061 19.5 2.0 1.5 8.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat SET PF00856.23 CDJ68886.1 - 0.031 14.5 0.0 0.12 12.6 0.0 2.1 1 0 0 1 1 1 0 SET domain TPR_16 PF13432.1 CDJ68886.1 - 0.12 13.1 18.6 0.24 12.1 2.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Prefoldin PF02996.12 CDJ68887.1 - 3.8e-20 71.7 0.5 5.3e-20 71.2 0.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4530 PF15039.1 CDJ68887.1 - 0.059 13.2 0.9 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) PDEase_I PF00233.14 CDJ68888.1 - 1.6e-14 54.2 0.2 4.1e-12 46.3 0.4 2.3 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CDJ68888.1 - 0.018 15.0 0.1 0.048 13.6 0.1 1.6 1 0 0 1 1 1 0 HD domain ASFV_J13L PF05568.6 CDJ68889.1 - 1.9 7.9 0.0 1.9 7.9 0.0 3.0 4 0 0 4 4 4 0 African swine fever virus J13L protein Drf_FH1 PF06346.7 CDJ68890.1 - 0.14 11.6 8.0 0.18 11.2 5.6 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 DUF2997 PF11211.3 CDJ68891.1 - 0.0094 15.3 1.0 0.034 13.5 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2997) LRR_4 PF12799.2 CDJ68891.1 - 0.12 11.9 0.6 0.45 10.2 0.1 1.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) SPX PF03105.14 CDJ68892.1 - 0.021 14.5 0.1 0.021 14.5 0.1 3.1 3 0 0 3 3 3 0 SPX domain Tau95 PF09734.4 CDJ68892.1 - 1.1 8.5 5.3 2 7.6 3.7 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit Cwf_Cwc_15 PF04889.7 CDJ68893.1 - 0.014 15.0 4.9 0.017 14.8 3.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF755 PF05501.6 CDJ68893.1 - 0.24 11.4 23.9 0.43 10.6 16.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Macoilin PF09726.4 CDJ68893.1 - 0.3 9.3 19.1 0.37 9.0 13.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 CDJ68893.1 - 0.46 9.2 9.2 0.58 8.8 6.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FAM60A PF15396.1 CDJ68893.1 - 0.49 10.1 5.3 0.64 9.7 3.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 CDJ68893.1 - 1 9.1 21.0 1.3 8.8 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.8 CDJ68893.1 - 1.1 8.6 13.3 0.11 11.8 6.4 1.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DNA_pol_viral_N PF00242.12 CDJ68893.1 - 2 7.3 11.5 2.2 7.2 8.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2146 PF10220.4 CDJ68893.1 - 2.5 5.9 7.7 3.3 5.5 5.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Apt1 PF10351.4 CDJ68893.1 - 3 6.5 10.2 3.6 6.3 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.6 CDJ68893.1 - 3.4 6.7 5.8 4.1 6.5 4.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.6 CDJ68893.1 - 3.8 5.4 17.4 5.6 4.9 12.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AvrE PF11725.3 CDJ68893.1 - 9.7 3.0 20.3 11 2.8 14.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF3395 PF11875.3 CDJ68894.1 - 0.0069 16.0 16.5 0.0069 16.0 11.5 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3395) Med15 PF09606.5 CDJ68894.1 - 0.2 9.7 40.0 0.0063 14.7 18.2 2.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ68894.1 - 1.3 8.3 8.1 9.3 5.5 4.3 2.3 2 0 0 2 2 2 0 Spt20 family AAA_23 PF13476.1 CDJ68894.1 - 1.7 8.9 8.4 6 7.1 3.9 2.1 2 0 0 2 2 2 0 AAA domain DUF3617 PF12276.3 CDJ68895.1 - 0.0087 15.5 9.1 0.0087 15.5 6.3 8.6 4 1 2 6 6 6 1 Protein of unknown function (DUF3617) SR-25 PF10500.4 CDJ68896.1 - 0.00012 21.6 31.5 0.00015 21.3 21.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AA_permease_N PF08403.5 CDJ68896.1 - 0.011 15.0 0.1 0.011 15.0 0.0 2.2 2 1 0 2 2 2 0 Amino acid permease N-terminal DUF1777 PF08648.7 CDJ68896.1 - 0.15 11.7 20.7 0.18 11.4 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Med19 PF10278.4 CDJ68896.1 - 0.22 11.1 32.8 0.07 12.8 20.7 1.5 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TATR PF03430.8 CDJ68896.1 - 0.29 9.7 15.5 0.35 9.4 10.8 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DNA_pol_viral_N PF00242.12 CDJ68896.1 - 0.32 9.9 13.2 0.37 9.7 9.1 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF1510 PF07423.6 CDJ68896.1 - 0.42 9.9 23.6 0.57 9.5 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 CDJ68896.1 - 0.52 9.4 10.6 0.62 9.1 7.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 CDJ68896.1 - 1.1 7.1 18.4 1.3 6.9 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CDJ68896.1 - 1.2 8.9 14.2 1.7 8.3 9.9 1.3 1 0 0 1 1 1 0 DDHD domain DUF2413 PF10310.4 CDJ68896.1 - 1.2 7.9 22.6 1.5 7.5 15.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Nucleo_P87 PF07267.6 CDJ68896.1 - 1.4 7.4 13.1 1.6 7.3 9.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Transformer PF06495.6 CDJ68896.1 - 1.8 8.4 13.5 2.1 8.2 9.4 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Apt1 PF10351.4 CDJ68896.1 - 1.9 7.2 15.8 2.2 7.0 11.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3807 PF12720.2 CDJ68896.1 - 2 8.5 21.9 3.4 7.8 15.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3827 PF12877.2 CDJ68896.1 - 2.1 6.3 13.6 2.3 6.2 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) GvpL_GvpF PF06386.6 CDJ68896.1 - 2.3 7.7 9.9 3.4 7.1 6.9 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF GAGA_bind PF06217.7 CDJ68896.1 - 3.3 7.5 16.9 4.3 7.2 11.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 CDJ68896.1 - 6.5 6.5 16.6 8.2 6.1 11.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region IncFII_repA PF02387.10 CDJ68896.1 - 7.2 5.6 17.2 9.2 5.3 11.9 1.2 1 0 0 1 1 1 0 IncFII RepA protein family DUF3896 PF13035.1 CDJ68897.1 - 0.67 10.0 2.9 1.8 8.6 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) IF-2B PF01008.12 CDJ68900.1 - 2.3e-20 72.7 0.0 2.8e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Phosphoprotein PF00922.12 CDJ68900.1 - 1.7 7.7 6.9 2.4 7.3 4.8 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF515 PF04415.7 CDJ68900.1 - 7.3 4.7 16.0 11 4.1 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Apt1 PF10351.4 CDJ68900.1 - 9.1 5.0 7.1 11 4.7 4.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain WD40 PF00400.27 CDJ68901.1 - 9.3e-09 34.8 29.8 0.0032 17.2 0.1 7.7 7 1 0 7 7 7 4 WD domain, G-beta repeat DUF2722 PF10846.3 CDJ68901.1 - 0.021 13.8 0.1 0.021 13.8 0.1 5.7 3 1 1 5 5 5 0 Protein of unknown function (DUF2722) Prok-JAB PF14464.1 CDJ68901.1 - 0.31 10.6 6.2 0.67 9.5 0.2 3.6 3 1 1 4 4 4 0 Prokaryotic homologs of the JAB domain Herpes_capsid PF06112.6 CDJ68902.1 - 0.0011 18.9 10.2 0.0011 18.9 7.1 3.4 3 0 0 3 3 3 3 Gammaherpesvirus capsid protein B9-C2 PF07162.6 CDJ68903.1 - 0.017 14.9 0.2 0.32 10.7 0.0 2.2 1 1 1 2 2 2 0 Ciliary basal body-associated, B9 protein Ustilago_mating PF05722.7 CDJ68903.1 - 0.053 12.8 0.3 0.053 12.8 0.2 1.8 2 0 0 2 2 2 0 Ustilago B locus mating-type protein SR-25 PF10500.4 CDJ68903.1 - 0.12 11.8 14.4 0.92 8.9 6.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 CDJ68903.1 - 0.21 11.6 6.0 1.1 9.2 2.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peripla_BP_4 PF13407.1 CDJ68903.1 - 0.46 9.7 5.0 0.74 9.1 3.4 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain TSA PF03249.8 CDJ68903.1 - 1.4 7.4 12.2 1.8 6.9 8.4 1.1 1 0 0 1 1 1 0 Type specific antigen CAF-1_p150 PF11600.3 CDJ68903.1 - 2.3 7.5 9.5 7.6 5.8 0.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UMP1 PF05348.6 CDJ68903.1 - 2.5 8.0 7.3 3.6 7.5 3.6 2.0 1 1 1 2 2 2 0 Proteasome maturation factor UMP1 Suf PF05843.9 CDJ68905.1 - 0.0036 17.0 3.6 0.025 14.3 2.1 1.9 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Med15 PF09606.5 CDJ68905.1 - 0.019 13.1 20.8 0.029 12.5 14.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ68905.1 - 0.052 12.8 3.8 0.04 13.2 1.6 1.5 2 0 0 2 2 2 0 Spt20 family Activator_LAG-3 PF11498.3 CDJ68905.1 - 0.44 9.2 25.6 0.6 8.8 17.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF788 PF05620.6 CDJ68905.1 - 0.71 9.7 3.3 1.3 8.8 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF3371 PF11851.3 CDJ68905.1 - 5.8 7.6 14.1 12 6.6 9.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) FimP PF09766.4 CDJ68905.1 - 7.1 5.5 15.9 11 5.0 11.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein AAA_23 PF13476.1 CDJ68905.1 - 9.4 6.5 10.2 0.56 10.4 3.5 1.5 2 0 0 2 2 2 0 AAA domain SLA_LP_auto_ag PF05889.8 CDJ68907.1 - 2.1e-15 56.0 3.5 2.9e-07 29.3 0.0 2.7 2 1 1 3 3 3 2 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DDRGK PF09756.4 CDJ68907.1 - 0.00066 19.1 16.8 0.00066 19.1 11.6 2.1 2 0 0 2 2 2 1 DDRGK domain DUF966 PF06136.8 CDJ68907.1 - 0.0026 17.2 16.1 0.0037 16.7 11.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF966) AIF_C PF14721.1 CDJ68907.1 - 0.089 13.0 20.9 0.093 12.9 3.3 3.0 2 1 1 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sporozoite_P67 PF05642.6 CDJ68907.1 - 0.11 10.3 15.0 0.14 9.9 10.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MRP-S31 PF15433.1 CDJ68907.1 - 0.13 11.7 30.8 0.035 13.5 16.9 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF4045 PF13254.1 CDJ68907.1 - 0.28 10.4 22.1 0.06 12.6 11.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Dapper PF15268.1 CDJ68907.1 - 0.31 9.7 31.5 0.43 9.3 21.8 1.1 1 0 0 1 1 1 0 Dapper SeqA PF03925.8 CDJ68907.1 - 0.31 10.7 24.1 0.44 10.2 14.3 2.1 2 0 0 2 2 2 0 SeqA protein Tim54 PF11711.3 CDJ68907.1 - 0.62 8.5 16.5 0.074 11.6 7.5 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pox_Ag35 PF03286.9 CDJ68907.1 - 0.69 9.3 16.2 0.15 11.5 7.9 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PAT1 PF09770.4 CDJ68907.1 - 0.83 7.8 62.5 0.1 10.8 36.2 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Gti1_Pac2 PF09729.4 CDJ68907.1 - 0.89 9.4 15.6 0.79 9.5 8.3 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Zip PF02535.17 CDJ68907.1 - 0.95 8.4 7.1 0.58 9.1 3.5 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter FAM60A PF15396.1 CDJ68907.1 - 1.4 8.6 20.9 0.47 10.1 11.1 1.9 2 0 0 2 2 2 0 Protein Family FAM60A DHHW PF14286.1 CDJ68907.1 - 1.5 8.0 22.0 0.22 10.8 12.0 1.9 2 0 0 2 2 2 0 DHHW protein TFIIA PF03153.8 CDJ68907.1 - 1.6 8.5 47.8 1.3 8.8 28.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Gag_spuma PF03276.9 CDJ68907.1 - 3.1 6.0 50.9 0.49 8.6 27.3 2.2 2 0 0 2 2 2 0 Spumavirus gag protein Raftlin PF15250.1 CDJ68907.1 - 4.1 5.8 23.8 1.5 7.2 13.6 1.9 2 0 0 2 2 2 0 Raftlin YjgP_YjgQ PF03739.9 CDJ68907.1 - 4.3 5.9 10.6 6.5 5.3 7.3 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Cellulose_synt PF03552.9 CDJ68907.1 - 4.6 5.4 8.7 6.6 4.8 6.1 1.2 1 0 0 1 1 1 0 Cellulose synthase FAM176 PF14851.1 CDJ68907.1 - 4.8 6.8 17.3 19 4.8 0.1 2.4 2 0 0 2 2 2 0 FAM176 family DnaJ-X PF14308.1 CDJ68907.1 - 6.6 5.9 23.7 3.6 6.8 11.9 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing AUX_IAA PF02309.11 CDJ68907.1 - 7.1 6.3 24.1 3.9 7.1 13.7 2.0 2 0 0 2 2 2 0 AUX/IAA family RNA_pol_Rpb1_5 PF04998.12 CDJ68907.1 - 7.4 5.7 15.3 2.3 7.4 8.5 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 SNARE PF05739.14 CDJ68909.1 - 2e-15 56.2 2.6 2e-15 56.2 1.8 2.0 3 0 0 3 3 3 1 SNARE domain TerB PF05099.8 CDJ68909.1 - 0.087 12.5 1.2 0.14 11.8 0.9 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TerB Synaptobrevin PF00957.16 CDJ68909.1 - 0.13 11.8 0.2 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Synaptobrevin DUF4131 PF13567.1 CDJ68910.1 - 0.22 10.9 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Spt20 PF12090.3 CDJ68910.1 - 0.79 9.0 8.5 0.57 9.5 1.5 2.5 2 0 0 2 2 2 0 Spt20 family Thioredoxin PF00085.15 CDJ68911.1 - 2.2e-39 133.3 0.0 5.8e-22 77.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CDJ68911.1 - 2.3e-11 43.8 0.0 3.9e-06 26.8 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CDJ68911.1 - 3.9e-08 33.4 0.0 0.0016 18.6 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDJ68911.1 - 5e-06 26.5 0.0 0.076 13.1 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CDJ68911.1 - 0.0025 17.7 0.0 0.32 11.0 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 CDJ68911.1 - 0.0036 16.9 0.0 0.68 9.6 0.0 3.1 3 0 0 3 3 3 1 AhpC/TSA family Redoxin PF08534.5 CDJ68911.1 - 0.022 14.2 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Redoxin ERp29_N PF07912.8 CDJ68911.1 - 0.032 14.1 0.0 7.8 6.4 0.0 3.4 2 1 0 2 2 2 0 ERp29, N-terminal domain Mucin PF01456.12 CDJ68911.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Thioredoxin_9 PF14595.1 CDJ68911.1 - 0.15 11.6 0.0 1.4 8.5 0.0 2.4 3 0 0 3 3 3 0 Thioredoxin RCC1 PF00415.13 CDJ68912.1 - 1e-65 217.7 39.4 5.1e-16 58.6 0.6 8.1 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ68912.1 - 9e-37 123.9 66.8 3.5e-09 36.0 1.6 8.7 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 CDJ68912.1 - 2.6e-05 23.5 0.9 0.19 11.1 0.0 3.8 4 0 0 4 4 4 2 Putative carbohydrate binding domain Hira PF07569.6 CDJ68912.1 - 0.001 18.3 0.0 0.92 8.6 0.0 3.7 4 0 0 4 4 4 1 TUP1-like enhancer of split Laminin_G_3 PF13385.1 CDJ68912.1 - 0.027 14.7 0.5 11 6.1 0.1 3.7 2 2 2 4 4 4 0 Concanavalin A-like lectin/glucanases superfamily Kelch_2 PF07646.10 CDJ68912.1 - 0.23 11.2 8.9 20 5.1 0.1 5.7 7 0 0 7 7 7 0 Kelch motif Ribosomal_L18p PF00861.17 CDJ68913.1 - 4.7e-39 133.2 0.1 9.7e-39 132.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CDJ68913.1 - 1.3e-32 112.1 5.7 2.9e-32 111.0 3.9 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Choline_sulf_C PF12411.3 CDJ68913.1 - 0.037 13.8 0.1 2.1 8.2 0.0 2.8 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal RNA_pol_Rbc25 PF08292.7 CDJ68914.1 - 2.7 8.2 8.2 0.65 10.1 0.3 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Bac_small_YrzI PF09501.5 CDJ68917.1 - 0.93 9.4 3.2 1 9.3 2.2 1.1 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Peptidase_M48 PF01435.13 CDJ68920.1 - 1e-42 146.2 0.0 1.4e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 CorA PF01544.13 CDJ68921.1 - 1.3e-05 24.4 0.1 1.3e-05 24.4 0.1 2.4 3 1 0 3 3 3 1 CorA-like Mg2+ transporter protein Claudin_2 PF13903.1 CDJ68921.1 - 0.02 14.5 0.1 0.02 14.5 0.1 3.0 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4613 PF15390.1 CDJ68921.1 - 8 4.4 15.1 15 3.6 10.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) BAF1_ABF1 PF04684.8 CDJ68922.1 - 0.014 14.3 8.4 0.021 13.7 5.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3_zeta PF05091.7 CDJ68923.1 - 0.066 11.8 9.9 0.11 11.1 6.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EphA2_TM PF14575.1 CDJ68923.1 - 0.43 11.0 4.7 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RAB3GAP2_N PF14655.1 CDJ68923.1 - 1 8.2 23.0 1 8.2 4.1 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4175 PF13779.1 CDJ68923.1 - 2.9 5.4 39.5 2.2 5.8 12.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Apt1 PF10351.4 CDJ68923.1 - 3.8 6.2 18.5 3 6.5 1.8 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain FimP PF09766.4 CDJ68923.1 - 6.3 5.7 33.5 7.7 5.4 6.3 2.7 3 0 0 3 3 3 0 Fms-interacting protein FHIPEP PF00771.15 CDJ68923.1 - 7.8 4.6 14.0 0.15 10.4 2.2 2.1 2 0 0 2 2 2 0 FHIPEP family SART-1 PF03343.8 CDJ68924.1 - 4.5e-12 45.1 13.3 8.3e-12 44.2 9.2 1.4 1 1 0 1 1 1 1 SART-1 family Med3 PF11593.3 CDJ68924.1 - 0.031 13.5 19.5 0.039 13.2 13.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hamartin PF04388.7 CDJ68924.1 - 0.16 10.6 8.2 0.18 10.4 5.7 1.1 1 0 0 1 1 1 0 Hamartin protein PRCC PF10253.4 CDJ68924.1 - 0.2 12.3 10.5 0.29 11.8 7.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SpoIIIAH PF12685.2 CDJ68924.1 - 0.32 10.4 6.6 0.44 10.0 4.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF566 PF04484.7 CDJ68924.1 - 0.36 10.3 13.9 0.44 10.0 9.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DASH_Spc19 PF08287.6 CDJ68924.1 - 0.54 9.8 4.7 0.08 12.5 0.4 1.7 2 0 0 2 2 2 0 Spc19 Corona_nucleoca PF00937.13 CDJ68924.1 - 0.61 8.9 10.1 0.85 8.5 7.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Ashwin PF15323.1 CDJ68924.1 - 2.3 8.1 6.7 3.5 7.5 4.6 1.3 1 0 0 1 1 1 0 Developmental protein NAM-associated PF14303.1 CDJ68924.1 - 4.4 7.6 11.2 4.3 7.6 7.1 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain MPP6 PF10175.4 CDJ68925.1 - 0.002 18.4 2.4 0.027 14.8 1.7 2.6 1 1 0 1 1 1 1 M-phase phosphoprotein 6 K_channel_TID PF07941.6 CDJ68925.1 - 0.0065 16.6 4.5 0.0065 16.6 3.1 2.2 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain Shadoo PF14999.1 CDJ68925.1 - 0.016 15.0 0.9 0.016 15.0 0.6 1.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RAB3GAP2_N PF14655.1 CDJ68925.1 - 0.038 12.9 0.9 0.055 12.4 0.6 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RskA PF10099.4 CDJ68925.1 - 0.52 10.0 9.1 0.035 13.8 2.8 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Cyt-b5 PF00173.23 CDJ68926.1 - 1.5e-08 34.3 0.0 1.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_60s PF00428.14 CDJ68926.1 - 0.019 15.3 14.3 0.019 15.3 9.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein PSCyt3 PF07627.6 CDJ68926.1 - 0.054 13.3 2.5 0.13 12.1 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) DUF3446 PF11928.3 CDJ68926.1 - 1 9.6 9.8 0.12 12.5 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Corona_nucleoca PF00937.13 CDJ68927.1 - 0.018 13.9 24.4 0.021 13.7 16.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med15 PF09606.5 CDJ68927.1 - 0.019 13.1 58.2 0.022 13.0 40.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ68927.1 - 0.026 14.2 24.0 0.03 14.0 16.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GAGA_bind PF06217.7 CDJ68927.1 - 0.03 14.3 20.0 0.038 13.9 13.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family eIF-3_zeta PF05091.7 CDJ68927.1 - 0.077 11.6 24.5 0.092 11.3 17.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.1 CDJ68927.1 - 0.09 12.5 19.5 0.1 12.3 13.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SOBP PF15279.1 CDJ68927.1 - 0.15 12.4 18.1 0.19 12.0 12.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 CDJ68927.1 - 0.19 9.9 49.7 0.21 9.8 34.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_DNAp_acc PF04929.7 CDJ68927.1 - 0.35 9.7 21.2 0.43 9.5 14.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MIP-T3 PF10243.4 CDJ68927.1 - 0.4 9.0 45.5 0.52 8.7 31.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Raftlin PF15250.1 CDJ68927.1 - 0.59 8.5 18.7 0.64 8.4 12.9 1.1 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.2 CDJ68927.1 - 0.6 7.7 19.0 0.62 7.6 13.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 CDJ68927.1 - 1 7.9 18.0 1.1 7.8 12.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein U79_P34 PF03064.11 CDJ68927.1 - 2.4 7.6 27.8 3.1 7.2 19.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Nop53 PF07767.6 CDJ68927.1 - 2.6 6.9 43.5 3.3 6.6 30.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SAGA-Tad1 PF12767.2 CDJ68927.1 - 3.6 7.1 28.5 4.5 6.8 19.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit MRP-S31 PF15433.1 CDJ68927.1 - 3.7 6.8 29.4 4.2 6.6 20.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Activator_LAG-3 PF11498.3 CDJ68927.1 - 3.7 6.1 61.6 5.1 5.7 42.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.8 CDJ68927.1 - 4 7.2 42.3 4.9 6.9 29.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.5 CDJ68927.1 - 4.3 5.6 17.4 4.3 5.6 12.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Parvo_coat PF00740.13 CDJ68927.1 - 4.4 6.1 21.9 4.8 6.0 15.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CDC27 PF09507.5 CDJ68927.1 - 5.2 6.1 37.2 5.8 6.0 25.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_S64 PF08192.6 CDJ68927.1 - 9.5 4.4 18.7 11 4.2 13.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 GBP_C PF02841.9 CDJ68927.1 - 9.9 5.2 35.6 13 4.9 24.7 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF401 PF04165.7 CDJ68928.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF401) DUF572 PF04502.8 CDJ68928.1 - 0.11 11.7 24.6 0.13 11.4 17.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2813 PF11398.3 CDJ68928.1 - 3.6 6.5 25.0 4.4 6.2 17.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) IZUMO PF15005.1 CDJ68928.1 - 5.8 6.9 20.4 7.5 6.5 14.2 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion PLRV_ORF5 PF01690.12 CDJ68928.1 - 6.8 5.7 14.4 8.1 5.4 10.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Hist_deacetyl PF00850.14 CDJ68928.1 - 7.2 5.7 7.5 9.3 5.4 5.2 1.2 1 0 0 1 1 1 0 Histone deacetylase domain DUF4071 PF13281.1 CDJ68928.1 - 8.2 5.1 17.4 9.6 4.9 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) PAT1 PF09770.4 CDJ68928.1 - 8.6 4.4 57.4 9.2 4.3 39.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 CDJ68928.1 - 9.7 3.8 17.2 13 3.4 11.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IER PF05760.7 CDJ68929.1 - 0.023 14.6 3.1 0.024 14.5 2.1 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF4653 PF15546.1 CDJ68929.1 - 0.12 11.6 2.8 0.15 11.2 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF2638 PF10937.3 CDJ68929.1 - 5.6 8.0 8.3 3.7 8.5 2.9 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF2638) UPF0128 PF03673.8 CDJ68930.1 - 0.055 12.7 2.0 3.9 6.6 0.1 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0128) 2OG-FeII_Oxy_3 PF13640.1 CDJ68931.1 - 0.00046 20.6 0.0 0.00089 19.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CDJ68931.1 - 0.0088 15.6 0.0 0.062 12.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Transket_pyr PF02779.19 CDJ68933.1 - 2.4e-31 108.6 0.1 3.7e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Xlink PF00193.12 CDJ68934.1 - 0.1 12.6 0.1 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Extracellular link domain MIF4G PF02854.14 CDJ68935.1 - 2.6e-20 72.7 0.0 3.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain Pyr_redox_dim PF02852.17 CDJ68935.1 - 0.15 12.0 0.1 3.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DUF1071 PF06378.6 CDJ68936.1 - 0.077 12.1 0.4 0.17 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) IF-2B PF01008.12 CDJ68938.1 - 3.9e-16 58.8 0.0 4.3e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2228 PF10228.4 CDJ68939.1 - 0.033 13.7 0.0 0.035 13.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Paramyx_P_V_C PF03210.8 CDJ68939.1 - 0.033 14.0 0.0 0.033 14.0 0.0 1.0 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Slu7 PF11708.3 CDJ68939.1 - 0.077 12.7 0.1 0.083 12.6 0.0 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF2312 PF10073.4 CDJ68939.1 - 0.09 12.1 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) TerB PF05099.8 CDJ68939.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB hDGE_amylase PF14701.1 CDJ68940.1 - 2.4e-96 323.2 0.1 1.4e-48 165.9 0.0 2.5 2 1 0 2 2 2 2 glucanotransferase domain of human glycogen debranching enzyme hGDE_central PF14702.1 CDJ68940.1 - 6.7e-29 100.8 0.0 2.6e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme GDE_C PF06202.9 CDJ68940.1 - 6.4e-20 71.1 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase BNIP3 PF06553.7 CDJ68940.1 - 0.0038 16.6 1.2 0.0076 15.6 0.8 1.4 1 0 0 1 1 1 1 BNIP3 Med15 PF09606.5 CDJ68941.1 - 0.00059 18.1 128.4 0.00081 17.7 89.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 CDJ68941.1 - 1.7 6.6 46.1 2 6.4 32.0 1.1 1 0 0 1 1 1 0 Utp14 protein DUF740 PF05340.7 CDJ68941.1 - 4.5 5.5 15.9 6 5.1 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Asp-B-Hydro_N PF05279.6 CDJ68941.1 - 8.1 6.2 32.3 10 5.8 22.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4613 PF15390.1 CDJ68941.1 - 8.8 4.3 29.3 10 4.1 20.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) RNB PF00773.14 CDJ68942.1 - 2.8e-28 99.1 3.4 5.5e-18 65.3 3.0 3.0 2 1 0 2 2 2 2 RNB domain DUF2217 PF10265.4 CDJ68942.1 - 0.021 13.6 10.2 0.029 13.1 7.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CDJ68942.1 - 0.025 12.6 12.6 0.031 12.4 8.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.1 CDJ68942.1 - 1.2 8.0 7.7 1.9 7.3 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SprA-related PF12118.3 CDJ68942.1 - 2.1 7.6 30.9 1.4 8.1 5.5 2.3 2 0 0 2 2 2 0 SprA-related family Ribosomal_60s PF00428.14 CDJ68942.1 - 3 8.2 13.9 1.1 9.6 5.0 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Corona_nucleoca PF00937.13 CDJ68942.1 - 4.8 6.0 24.2 4.3 6.1 9.1 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF572 PF04502.8 CDJ68942.1 - 9.3 5.3 16.6 17 4.5 11.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) FimP PF09766.4 CDJ68943.1 - 0.22 10.5 18.2 0.029 13.4 8.6 1.9 2 0 0 2 2 2 0 Fms-interacting protein DUF2190 PF09956.4 CDJ68943.1 - 0.54 10.0 15.7 0.98 9.2 10.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) Med15 PF09606.5 CDJ68943.1 - 0.88 7.6 50.7 1.1 7.4 35.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Paramyxo_ncap PF00973.14 CDJ68943.1 - 0.9 8.1 9.8 0.59 8.7 5.9 1.3 1 1 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vps39_1 PF10366.4 CDJ68943.1 - 5.8 6.9 12.0 2.1 8.3 6.3 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Ribosomal_60s PF00428.14 CDJ68944.1 - 0.46 10.9 2.6 0.45 10.9 0.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ycf1 PF05758.7 CDJ68945.1 - 0.17 9.5 7.1 0.0054 14.5 0.6 1.6 2 0 0 2 2 2 0 Ycf1 LMBR1 PF04791.11 CDJ68945.1 - 0.43 9.0 2.3 3 6.3 0.8 2.3 2 0 0 2 2 2 0 LMBR1-like membrane protein Jun PF03957.8 CDJ68946.1 - 0.029 14.0 0.4 0.033 13.9 0.3 1.0 1 0 0 1 1 1 0 Jun-like transcription factor Ribosomal_60s PF00428.14 CDJ68946.1 - 0.15 12.5 4.4 0.16 12.3 3.0 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Trehalase PF01204.13 CDJ68950.1 - 9.6e-66 222.4 0.1 1.3e-65 222.0 0.1 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 CDJ68950.1 - 1.5e-06 27.1 0.2 3.3e-06 26.0 0.1 1.4 1 1 1 2 2 2 1 Amylo-alpha-1,6-glucosidase PP2C PF00481.16 CDJ68951.1 - 1.9e-36 125.7 0.0 2.9e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CDJ68951.1 - 2e-07 30.8 0.0 3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CDJ68951.1 - 3.8e-06 26.4 0.0 0.0083 15.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C 4HBT_3 PF13622.1 CDJ68952.1 - 0.0067 16.2 0.3 0.0067 16.2 0.2 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily CSD PF00313.17 CDJ68953.1 - 3.1e-24 84.5 0.6 4.4e-24 84.0 0.4 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CDJ68953.1 - 0.00047 19.5 0.8 0.0011 18.3 0.6 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.18 CDJ68953.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain Anticodon_1 PF08264.8 CDJ68954.1 - 0.00035 20.3 0.0 0.00041 20.1 0.0 1.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA APC_CDC26 PF10471.4 CDJ68954.1 - 0.53 11.0 11.0 0.85 10.4 7.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 TSA PF03249.8 CDJ68954.1 - 5.9 5.3 9.0 7.8 4.9 6.2 1.2 1 0 0 1 1 1 0 Type specific antigen DUF1077 PF06417.7 CDJ68956.1 - 1.4e-11 43.7 0.0 2.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CHAD PF05235.9 CDJ68956.1 - 0.0051 16.4 1.3 0.006 16.2 0.9 1.2 1 0 0 1 1 1 1 CHAD domain DUF3138 PF11336.3 CDJ68956.1 - 0.03 12.5 10.1 0.039 12.1 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) 3-alpha PF03475.9 CDJ68956.1 - 0.24 11.1 2.5 0.52 10.0 1.8 1.5 1 0 0 1 1 1 0 3-alpha domain Pkinase PF00069.20 CDJ68957.1 - 0.00036 19.7 0.1 0.00036 19.7 0.0 4.7 5 1 0 5 5 5 1 Protein kinase domain PHF5 PF03660.9 CDJ68959.1 - 2e-48 162.8 12.0 2.2e-48 162.7 8.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 CDJ68959.1 - 0.22 9.1 5.9 0.25 8.9 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 SET PF00856.23 CDJ68960.1 - 1.1e-21 77.8 0.1 1.1e-21 77.8 0.1 3.8 3 1 0 3 3 3 1 SET domain Ycf1 PF05758.7 CDJ68960.1 - 5.1 4.6 17.6 7.8 4.0 12.2 1.1 1 0 0 1 1 1 0 Ycf1 Phage_GPD PF05954.6 CDJ68964.1 - 0.052 12.7 0.9 0.062 12.4 0.6 1.0 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) DUF2201_N PF13203.1 CDJ68964.1 - 5.9 5.9 10.8 6.7 5.7 7.5 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain FH2 PF02181.18 CDJ68965.1 - 1.3e-38 132.9 0.0 2.4e-27 95.8 0.0 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain PTEN_C2 PF10409.4 CDJ68965.1 - 0.92 9.2 0.0 2.3 7.9 0.0 1.7 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Bromodomain PF00439.20 CDJ68967.1 - 4.6e-23 80.9 0.4 1e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CDJ68967.1 - 5.3e-11 42.5 1.6 1e-10 41.5 1.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDJ68967.1 - 1.8e-10 40.6 0.1 4.5e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CDJ68967.1 - 1.6e-05 25.0 0.0 4.5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDJ68967.1 - 0.0066 16.6 0.0 0.055 13.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDJ68967.1 - 0.0088 15.7 0.0 0.026 14.2 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CDJ68967.1 - 0.01 15.6 0.0 0.035 13.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GHL12 PF14882.1 CDJ68967.1 - 0.039 14.0 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 Ribosomal_L3 PF00297.17 CDJ68968.1 - 7.9e-23 81.1 1.3 2.5e-20 72.9 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L3 DNA_pol_A PF00476.15 CDJ68970.1 - 0.071 11.7 0.0 0.074 11.6 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase family A Phosphodiest PF01663.17 CDJ68972.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3273 PF11677.3 CDJ68973.1 - 3.5e-79 265.7 3.9 3.9e-79 265.6 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) UQ_con PF00179.21 CDJ68974.1 - 6.8e-38 129.2 0.0 9.6e-38 128.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDJ68974.1 - 0.091 12.6 0.1 0.24 11.3 0.1 1.8 1 1 0 1 1 1 0 RWD domain NA37 PF04245.8 CDJ68974.1 - 0.19 10.9 1.8 0.28 10.4 1.2 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Trypsin_2 PF13365.1 CDJ68975.1 - 1.2e-14 54.3 0.1 2.5e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CDJ68975.1 - 5.5e-13 49.0 0.4 9e-13 48.3 0.3 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 CDJ68975.1 - 4.3e-11 42.5 0.1 9.4e-09 35.0 0.0 3.1 3 0 0 3 3 3 1 PDZ domain Peptidase_S7 PF00949.16 CDJ68975.1 - 0.00031 20.1 0.0 0.00071 18.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease PDZ PF00595.19 CDJ68975.1 - 0.0038 17.3 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 CDJ68975.1 - 0.087 11.2 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_C2 PF00648.16 CDJ68975.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Calpain family cysteine protease PRTase_1 PF11202.3 CDJ68977.1 - 0.56 9.1 2.6 0.93 8.4 1.8 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) PAT1 PF09770.4 CDJ68977.1 - 9.5 4.3 20.4 15 3.6 14.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDJ68978.1 - 0.00028 20.9 4.8 0.00037 20.5 3.3 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDJ68978.1 - 0.00087 19.1 6.2 0.00087 19.0 4.3 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ68978.1 - 0.001 18.2 12.5 0.0012 18.0 8.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4557 PF15101.1 CDJ68978.1 - 0.0014 18.5 6.9 0.0014 18.5 4.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) FHIPEP PF00771.15 CDJ68978.1 - 0.0034 15.7 1.1 0.0036 15.7 0.8 1.0 1 0 0 1 1 1 1 FHIPEP family Spt20 PF12090.3 CDJ68978.1 - 0.0047 16.2 5.9 0.0061 15.9 4.1 1.3 1 0 0 1 1 1 1 Spt20 family DUF4175 PF13779.1 CDJ68978.1 - 0.0048 14.6 20.9 0.0056 14.4 14.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DUF912 PF06024.7 CDJ68978.1 - 0.0075 16.3 2.0 0.013 15.5 1.4 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S49_N PF08496.5 CDJ68978.1 - 0.0077 16.0 0.9 0.0079 16.0 0.7 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal PH_4 PF15404.1 CDJ68978.1 - 0.013 15.0 2.1 0.014 14.9 1.5 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF106 PF01956.11 CDJ68978.1 - 0.014 14.9 2.0 0.016 14.7 1.4 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2828 PF11443.3 CDJ68978.1 - 0.016 13.4 1.2 0.016 13.4 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Glyco_hydro_1 PF00232.13 CDJ68978.1 - 0.017 13.3 0.2 0.017 13.3 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 RAB3GAP2_N PF14655.1 CDJ68978.1 - 0.018 14.0 6.0 0.024 13.6 4.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 CDJ68978.1 - 0.026 13.2 2.0 0.029 13.0 1.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) TRP PF06011.7 CDJ68978.1 - 0.028 13.0 0.3 0.028 13.0 0.2 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Band_3_cyto PF07565.8 CDJ68978.1 - 0.032 13.7 4.6 0.032 13.7 3.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BRF1 PF07741.8 CDJ68978.1 - 0.033 14.3 3.9 0.051 13.7 2.7 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF1266 PF06889.6 CDJ68978.1 - 0.035 13.9 1.9 0.037 13.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) SprA-related PF12118.3 CDJ68978.1 - 0.042 13.1 19.8 0.045 13.0 13.7 1.1 1 0 0 1 1 1 0 SprA-related family DDHD PF02862.12 CDJ68978.1 - 0.056 13.2 2.6 0.066 13.0 1.8 1.2 1 0 0 1 1 1 0 DDHD domain SeqA PF03925.8 CDJ68978.1 - 0.057 13.1 3.7 0.088 12.5 2.6 1.3 1 0 0 1 1 1 0 SeqA protein Folliculin PF11704.3 CDJ68978.1 - 0.061 12.8 2.8 0.084 12.4 2.0 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Plasmodium_Vir PF05795.6 CDJ68978.1 - 0.062 12.4 0.4 0.066 12.4 0.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4199 PF13858.1 CDJ68978.1 - 0.069 13.0 1.4 0.1 12.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Peroxin-13_N PF04088.8 CDJ68978.1 - 0.089 12.7 1.0 0.11 12.3 0.7 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Med15 PF09606.5 CDJ68978.1 - 0.11 10.6 30.3 0.12 10.5 21.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glyco_transf_15 PF01793.11 CDJ68978.1 - 0.11 11.3 2.8 0.12 11.2 1.9 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase EIIBC-GUT_N PF03612.9 CDJ68978.1 - 0.11 12.0 3.5 0.15 11.6 2.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF607 PF04678.8 CDJ68978.1 - 0.12 12.2 2.7 0.13 12.1 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Gti1_Pac2 PF09729.4 CDJ68978.1 - 0.12 12.1 2.2 0.15 11.9 1.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Kei1 PF08552.6 CDJ68978.1 - 0.13 11.9 0.5 0.14 11.8 0.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Paramyxo_PCT PF14320.1 CDJ68978.1 - 0.13 11.1 1.7 0.17 10.7 1.2 1.1 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered OATP PF03137.15 CDJ68978.1 - 0.13 10.2 3.0 0.15 10.0 2.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Cnd2 PF05786.9 CDJ68978.1 - 0.14 10.6 6.2 0.17 10.3 4.3 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Ctr PF04145.10 CDJ68978.1 - 0.14 12.2 2.0 0.18 11.8 1.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family WES_acyltransf PF03007.11 CDJ68978.1 - 0.15 11.6 1.7 0.19 11.2 1.2 1.1 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1800 PF08811.6 CDJ68978.1 - 0.16 10.9 7.6 0.16 10.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Pex16 PF08610.5 CDJ68978.1 - 0.21 10.5 4.8 0.25 10.3 3.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF506 PF04720.7 CDJ68978.1 - 0.23 11.0 3.5 0.31 10.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) YfhO PF09586.5 CDJ68978.1 - 0.24 9.3 3.5 0.27 9.1 2.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO eIF-3_zeta PF05091.7 CDJ68978.1 - 0.25 9.9 8.7 0.27 9.7 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Folate_carrier PF01770.13 CDJ68978.1 - 0.27 9.7 3.1 0.34 9.3 2.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier FCP1_C PF09309.5 CDJ68978.1 - 0.28 10.4 9.7 0.37 10.0 6.7 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Di19_C PF14571.1 CDJ68978.1 - 0.32 11.3 7.4 0.47 10.7 5.1 1.3 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Ufd2P_core PF10408.4 CDJ68978.1 - 0.38 8.9 7.5 0.43 8.7 5.2 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core FlaG PF03646.10 CDJ68978.1 - 0.39 10.8 15.8 0.63 10.2 11.0 1.2 1 0 0 1 1 1 0 FlaG protein ERF PF04404.7 CDJ68978.1 - 0.41 10.1 15.1 0.65 9.5 10.5 1.3 1 0 0 1 1 1 0 ERF superfamily Med13_N PF11597.3 CDJ68978.1 - 0.44 9.1 6.3 0.55 8.8 4.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF775 PF05603.7 CDJ68978.1 - 0.45 9.9 7.4 0.58 9.6 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PAT1 PF09770.4 CDJ68978.1 - 0.52 8.4 22.9 0.57 8.3 15.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1764 PF08576.5 CDJ68978.1 - 0.67 10.7 9.9 1 10.1 6.9 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) zf-DHHC PF01529.15 CDJ68978.1 - 0.72 9.2 2.8 0.89 8.9 1.9 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF2324 PF10086.4 CDJ68978.1 - 0.73 8.9 3.5 1.1 8.3 2.4 1.3 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) DUF3853 PF12964.2 CDJ68978.1 - 0.94 9.3 5.8 0.65 9.8 1.2 2.3 1 1 2 3 3 2 0 Protein of unknown function (DUF3853) BAF1_ABF1 PF04684.8 CDJ68978.1 - 1.1 8.0 26.1 1.3 7.7 18.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF788 PF05620.6 CDJ68978.1 - 1.1 9.0 11.1 1.8 8.3 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Anoctamin PF04547.7 CDJ68978.1 - 1.4 7.5 5.2 1.5 7.4 3.6 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel RR_TM4-6 PF06459.7 CDJ68978.1 - 1.4 8.7 7.9 1.8 8.3 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.3 CDJ68978.1 - 1.5 8.2 6.4 2.1 7.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) PEX11 PF05648.9 CDJ68978.1 - 1.6 7.9 6.3 0.62 9.2 2.8 1.4 2 0 0 2 2 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF3154 PF11351.3 CDJ68978.1 - 1.9 8.2 8.0 2.9 7.6 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) AIF_C PF14721.1 CDJ68978.1 - 2.1 8.6 6.6 3 8.1 4.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2633 PF11119.3 CDJ68978.1 - 2.1 8.1 11.3 5.5 6.7 7.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2633) DUF3371 PF11851.3 CDJ68978.1 - 3.3 8.4 14.6 0.54 10.9 7.5 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF3371) DUF3043 PF11241.3 CDJ68978.1 - 3.5 7.1 9.7 5.2 6.6 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF945 PF06097.6 CDJ68978.1 - 3.5 6.2 16.0 4.7 5.8 11.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) DUF533 PF04391.7 CDJ68978.1 - 4.7 6.5 14.1 7.2 5.9 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) AAA_23 PF13476.1 CDJ68978.1 - 5.2 7.3 14.8 6.4 7.0 10.3 1.2 1 0 0 1 1 1 0 AAA domain RED_N PF07808.8 CDJ68978.1 - 5.4 6.1 16.0 7.4 5.7 11.1 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region UPF0560 PF10577.4 CDJ68978.1 - 5.8 5.0 14.0 7 4.7 9.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4407 PF14362.1 CDJ68978.1 - 6 5.7 12.1 7.9 5.3 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3405 PF11885.3 CDJ68978.1 - 7.4 4.6 8.7 9.7 4.2 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) G0-G1_switch_2 PF15103.1 CDJ68978.1 - 9.6 6.4 9.8 18 5.6 6.8 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Fcf1 PF04900.7 CDJ68979.1 - 5.7e-11 42.4 0.4 0.00025 21.0 0.0 2.7 2 0 0 2 2 2 2 Fcf1 Ndc1_Nup PF09531.5 CDJ68979.1 - 5.9 5.1 11.6 7.7 4.8 8.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 CDJ68980.1 - 5.9e-10 38.3 6.8 0.001 17.8 9.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Chorion_2 PF03964.10 CDJ68980.1 - 0.011 16.3 0.7 0.011 16.3 0.5 4.4 3 1 1 4 4 4 0 Chorion family 2 7tm_1 PF00001.16 CDJ68980.1 - 0.04 13.0 0.3 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Suf PF05843.9 CDJ68980.1 - 0.04 13.6 4.6 0.77 9.4 2.8 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2140 PF09911.4 CDJ68980.1 - 0.043 12.9 0.1 0.1 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Alpha-mann_mid PF09261.6 CDJ68980.1 - 0.081 13.1 1.6 7.9 6.7 0.6 2.6 2 0 0 2 2 2 0 Alpha mannosidase, middle domain Ferric_reduct PF01794.14 CDJ68980.1 - 0.12 12.4 2.2 0.74 9.9 0.1 2.4 2 1 0 2 2 2 0 Ferric reductase like transmembrane component OATP PF03137.15 CDJ68980.1 - 0.35 8.8 11.5 0.13 10.3 1.0 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PAT1 PF09770.4 CDJ68980.1 - 2.5 6.2 21.2 4 5.5 14.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EphA2_TM PF14575.1 CDJ68980.1 - 4.2 7.8 8.7 2.7 8.4 1.0 3.5 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF808 PF05661.7 CDJ68981.1 - 0.59 8.9 3.5 0.41 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF808) SR-25 PF10500.4 CDJ68981.1 - 1.9 7.8 39.4 0.029 13.8 2.3 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein AAA_23 PF13476.1 CDJ68981.1 - 3.3 7.9 16.6 2.2 8.5 6.0 2.2 2 0 0 2 2 2 0 AAA domain BBS2_C PF14782.1 CDJ68981.1 - 4.7 5.6 18.0 0.69 8.4 7.2 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal CSD PF00313.17 CDJ68982.1 - 1e-05 25.2 0.0 3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CDJ68982.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain Filamin PF00630.14 CDJ68983.1 - 0.0099 16.4 0.0 0.025 15.1 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Kinesin PF00225.18 CDJ68984.1 - 1.6e-73 247.2 0.0 1.6e-73 247.2 0.0 5.9 5 2 0 6 6 6 1 Kinesin motor domain Init_tRNA_PT PF04179.7 CDJ68985.1 - 0.0022 16.9 0.1 0.0028 16.5 0.1 1.3 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PSI_PsaF PF02507.10 CDJ68985.1 - 0.57 9.7 3.1 1 8.8 2.1 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III TFIIA PF03153.8 CDJ68985.1 - 5.6 6.7 41.4 0.59 9.9 18.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ68985.1 - 8.2 4.5 70.8 1.5 7.0 34.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PAT1 PF09770.4 CDJ68986.1 - 4.6e-05 21.8 82.8 5.4e-05 21.6 57.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 CDJ68987.1 - 5.6e-24 83.1 8.7 1.9e-06 27.5 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDJ68987.1 - 1.8e-05 23.6 0.0 0.0018 17.1 0.0 2.4 3 0 0 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.1 CDJ68987.1 - 0.015 14.3 0.5 0.65 9.0 0.0 2.9 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.1 CDJ68987.1 - 1.2 8.0 0.0 1.2 8.0 0.0 3.5 4 1 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_60s PF00428.14 CDJ68988.1 - 0.067 13.6 9.0 0.084 13.2 6.2 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein CAF-1_p150 PF11600.3 CDJ68989.1 - 0.11 11.8 15.3 0.39 10.0 5.4 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FimP PF09766.4 CDJ68989.1 - 0.11 11.4 16.0 0.19 10.7 11.1 1.3 1 0 0 1 1 1 0 Fms-interacting protein TFIIA PF03153.8 CDJ68989.1 - 0.26 11.1 26.8 0.33 10.7 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.1 CDJ68989.1 - 2.8 8.1 12.0 5 7.4 8.3 1.4 1 1 0 1 1 1 0 AAA domain Peptidase_M3 PF01432.15 CDJ68991.1 - 4.8e-12 45.6 1.1 6e-12 45.3 0.7 1.3 1 1 0 1 1 1 1 Peptidase family M3 TBCC PF07986.7 CDJ68992.1 - 1 8.7 7.1 12 5.3 1.1 2.6 1 1 1 2 2 2 0 Tubulin binding cofactor C FAST_2 PF08368.7 CDJ68994.1 - 0.0098 16.2 0.2 0.0098 16.2 0.1 2.9 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 2 ER_lumen_recept PF00810.13 CDJ68995.1 - 1.1e-07 32.4 0.1 1.9e-05 25.1 0.0 2.5 1 1 1 2 2 2 1 ER lumen protein retaining receptor PIG-P PF08510.7 CDJ68995.1 - 0.00063 19.3 0.1 0.43 10.2 0.0 2.3 2 0 0 2 2 2 2 PIG-P DUF755 PF05501.6 CDJ68995.1 - 0.0084 16.1 37.4 0.0084 16.1 25.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF755) DUF2413 PF10310.4 CDJ68995.1 - 0.014 14.1 16.9 0.021 13.6 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF572 PF04502.8 CDJ68995.1 - 0.03 13.5 22.5 0.049 12.8 9.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Caa3_CtaG PF09678.5 CDJ68995.1 - 0.068 12.0 1.1 2.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) SID-1_RNA_chan PF13965.1 CDJ68995.1 - 0.072 11.2 7.7 0.28 9.3 2.0 2.0 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 DUF788 PF05620.6 CDJ68995.1 - 0.16 11.8 0.2 0.16 11.8 0.1 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF788) Patched PF02460.13 CDJ68995.1 - 0.22 9.3 3.2 0.086 10.7 0.4 1.5 1 1 0 1 1 1 0 Patched family CDK2AP PF09806.4 CDJ68995.1 - 0.3 11.2 29.2 0.59 10.3 11.7 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF2215 PF10225.4 CDJ68995.1 - 0.37 10.2 12.6 0.49 9.8 5.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) GPCR_chapero_1 PF11904.3 CDJ68995.1 - 0.6 9.1 12.6 0.015 14.4 1.3 2.0 2 0 0 2 2 2 0 GPCR-chaperone DUF2217 PF10265.4 CDJ68995.1 - 0.73 8.5 21.2 0.024 13.4 9.5 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) DUF3513 PF12026.3 CDJ68995.1 - 0.79 9.2 22.9 0.042 13.3 5.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) G0-G1_switch_2 PF15103.1 CDJ68995.1 - 1 9.6 14.3 0.34 11.1 1.1 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Tir_receptor_N PF07490.6 CDJ68995.1 - 1 8.8 8.7 0.054 13.1 1.4 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus TOM20_plant PF06552.7 CDJ68995.1 - 1.1 8.7 8.5 5.2 6.6 2.2 2.1 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2149 PF09919.4 CDJ68995.1 - 1.9 8.6 11.8 1.3 9.2 2.6 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) BBS2_C PF14782.1 CDJ68995.1 - 2 6.9 18.4 0.03 12.8 3.7 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal RAP1 PF07218.6 CDJ68995.1 - 3.6 5.5 12.6 4.7 5.1 8.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SPX PF03105.14 CDJ68995.1 - 4.1 7.1 24.2 7.4 6.2 16.8 1.4 1 1 0 1 1 1 0 SPX domain FLO_LFY PF01698.11 CDJ68995.1 - 4.2 6.1 15.6 4.3 6.0 5.2 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF912 PF06024.7 CDJ68995.1 - 4.5 7.3 19.1 0.76 9.8 0.1 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SSP160 PF06933.6 CDJ68995.1 - 4.8 5.0 13.8 6.4 4.6 9.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cwf_Cwc_15 PF04889.7 CDJ68995.1 - 5.7 6.5 27.2 0.32 10.6 8.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF1645 PF07816.6 CDJ68995.1 - 9.8 6.5 25.4 0.76 10.2 10.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Amidohydro_2 PF04909.9 CDJ68996.1 - 0.56 9.7 7.8 1 8.8 5.4 1.3 1 0 0 1 1 1 0 Amidohydrolase YndJ PF14158.1 CDJ68996.1 - 0.71 8.8 9.4 1.2 8.1 6.5 1.2 1 0 0 1 1 1 0 YndJ-like protein His_Phos_1 PF00300.17 CDJ68997.1 - 5.4e-42 143.5 0.0 8.2e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Activator_LAG-3 PF11498.3 CDJ68998.1 - 0.02 13.6 16.0 0.026 13.3 11.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GSK-3_bind PF05350.7 CDJ68998.1 - 0.026 13.9 5.0 0.033 13.6 3.5 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Med15 PF09606.5 CDJ68998.1 - 0.19 9.8 16.7 0.23 9.6 11.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_primase_lrg PF04104.9 CDJ68999.1 - 1.6e-28 99.6 0.0 1.8e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit RAB3GAP2_N PF14655.1 CDJ69000.1 - 0.076 11.9 2.4 0.091 11.7 1.6 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Apc15p PF05841.6 CDJ69000.1 - 0.21 12.3 7.3 0.26 12.0 5.1 1.1 1 0 0 1 1 1 0 Apc15p protein Gly-zipper_OmpA PF13436.1 CDJ69000.1 - 0.23 11.1 18.9 0.29 10.8 13.1 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Hist_deacetyl PF00850.14 CDJ69000.1 - 0.46 9.7 3.4 0.56 9.4 2.3 1.1 1 0 0 1 1 1 0 Histone deacetylase domain Med15 PF09606.5 CDJ69000.1 - 1 7.4 20.5 1.2 7.2 14.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal APC_CDC26 PF10471.4 CDJ69000.1 - 1.1 10.1 13.5 1.7 9.4 9.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 WES_acyltransf PF03007.11 CDJ69000.1 - 1.4 8.3 7.7 1.6 8.2 5.4 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DLIC PF05783.6 CDJ69000.1 - 2.6 6.6 5.4 3 6.4 3.8 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF4557 PF15101.1 CDJ69000.1 - 2.7 7.8 9.1 3.1 7.5 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CDK2AP PF09806.4 CDJ69000.1 - 2.8 8.1 16.5 3.3 7.8 11.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Activator_LAG-3 PF11498.3 CDJ69000.1 - 3 6.4 19.4 3.6 6.2 13.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0560 PF10577.4 CDJ69000.1 - 3.1 5.9 7.5 3 5.9 5.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 E_Pc_C PF06752.7 CDJ69000.1 - 3.2 7.2 22.5 4 6.8 15.6 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF2486 PF10667.4 CDJ69000.1 - 3.9 7.9 15.9 4.2 7.8 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) TFIIA PF03153.8 CDJ69000.1 - 6.2 6.6 12.9 7.1 6.4 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.8 CDJ69000.1 - 7 6.9 8.6 9.7 6.4 6.0 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PS_Dcarbxylase PF02666.10 CDJ69001.1 - 6.7e-25 87.5 0.2 3.7e-23 81.8 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase FAM60A PF15396.1 CDJ69003.1 - 0.6 9.8 8.6 0.68 9.6 5.9 1.0 1 0 0 1 1 1 0 Protein Family FAM60A PTN_MK_N PF05196.8 CDJ69003.1 - 0.64 10.0 0.3 0.64 10.0 0.2 2.3 2 1 1 3 3 3 0 PTN/MK heparin-binding protein family, N-terminal domain DUF4407 PF14362.1 CDJ69003.1 - 0.99 8.3 22.5 1.2 8.0 15.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 CDJ69003.1 - 2.3 8.6 11.2 3.4 8.0 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF605 PF04652.11 CDJ69003.1 - 4.6 6.5 16.9 6 6.1 11.7 1.2 1 0 0 1 1 1 0 Vta1 like DUF4175 PF13779.1 CDJ69003.1 - 5.7 4.5 42.1 7.5 4.1 29.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.11 CDJ69003.1 - 9.5 6.0 11.1 12 5.7 7.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SNARE PF05739.14 CDJ69004.1 - 7.8e-13 47.9 2.6 7.8e-13 47.9 1.8 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CDJ69004.1 - 5.8e-10 39.2 0.8 5.8e-10 39.2 0.6 2.3 2 0 0 2 2 2 1 Syntaxin F_actin_bind PF08919.5 CDJ69004.1 - 0.0024 17.5 0.8 0.012 15.3 0.1 2.3 2 0 0 2 2 2 1 F-actin binding Syntaxin-6_N PF09177.6 CDJ69004.1 - 0.0035 17.7 2.3 0.21 12.0 0.1 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Tup_N PF08581.5 CDJ69004.1 - 0.015 15.4 2.1 0.17 12.0 0.3 2.6 2 0 0 2 2 2 0 Tup N-terminal HhH-GPD PF00730.20 CDJ69004.1 - 0.019 15.2 0.1 0.04 14.1 0.0 1.8 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Sod_Ni PF09055.6 CDJ69004.1 - 0.039 14.3 0.4 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase Rho_N PF07498.7 CDJ69004.1 - 0.04 13.6 0.2 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Vac_Fusion PF02346.11 CDJ69004.1 - 0.083 12.3 3.3 1.8 8.0 0.0 3.1 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF148 PF02520.12 CDJ69004.1 - 0.63 9.8 6.9 0.73 9.6 0.2 3.2 2 1 2 4 4 4 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.7 CDJ69004.1 - 1.7 8.4 5.6 15 5.4 0.1 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1896 PF08989.5 CDJ69005.1 - 0.44 10.4 2.9 0.69 9.7 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) Ribosomal_60s PF00428.14 CDJ69005.1 - 0.81 10.1 18.1 1.3 9.5 12.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Rifin_STEVOR PF02009.11 CDJ69005.1 - 3.9 7.0 6.0 4.7 6.7 4.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Macoilin PF09726.4 CDJ69005.1 - 5.4 5.1 15.9 6.5 4.8 11.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 CDJ69005.1 - 7.6 5.4 15.8 7.6 5.4 10.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain FimP PF09766.4 CDJ69006.1 - 0.0019 17.3 5.4 0.0019 17.3 3.8 2.2 2 0 0 2 2 2 2 Fms-interacting protein Spt20 PF12090.3 CDJ69006.1 - 0.0044 16.3 1.8 0.054 12.8 0.1 2.3 2 0 0 2 2 2 1 Spt20 family TFIIA PF03153.8 CDJ69006.1 - 1.2 8.9 34.4 2.2 8.0 23.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3121 PF11319.3 CDJ69006.1 - 8.9 5.7 16.7 1.8 8.0 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) BCDHK_Adom3 PF10436.4 CDJ69007.1 - 3.9e-08 32.9 0.0 7.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CDJ69007.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Secretin_N_2 PF07655.8 CDJ69007.1 - 1.5 9.2 28.6 4.6 7.7 6.2 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Pheromone PF08015.6 CDJ69007.1 - 3.3 8.6 21.7 1.5 9.7 4.5 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone DUF605 PF04652.11 CDJ69007.1 - 4.6 6.5 17.9 5.7 6.2 12.4 1.1 1 0 0 1 1 1 0 Vta1 like Myco_19_kDa PF05481.7 CDJ69007.1 - 5.2 6.8 20.4 2.2 8.0 4.7 2.2 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen HATPase_c PF02518.21 CDJ69008.1 - 2.6e-06 27.1 0.0 8.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pex14_N PF04695.8 CDJ69008.1 - 0.23 11.5 7.2 0.34 10.9 5.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.1 CDJ69008.1 - 0.66 7.6 14.7 0.79 7.3 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gastrin PF00918.12 CDJ69008.1 - 1.4 9.7 8.5 2 9.2 5.9 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PAT1 PF09770.4 CDJ69008.1 - 1.9 6.5 14.0 2.2 6.3 9.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lipase_3 PF01764.20 CDJ69009.1 - 3.3e-11 42.9 0.0 1.2e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CDJ69009.1 - 0.0029 17.0 0.1 0.0071 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AAA_23 PF13476.1 CDJ69009.1 - 0.035 14.4 1.4 0.049 13.9 1.0 1.2 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.9 CDJ69009.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF3722 PF12519.3 CDJ69010.1 - 0.023 13.9 0.6 0.042 13.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) SAND PF01342.16 CDJ69010.1 - 0.082 12.6 2.8 0.12 12.1 0.6 2.1 2 0 0 2 2 2 0 SAND domain APC_CDC26 PF10471.4 CDJ69012.1 - 0.023 15.4 1.5 0.023 15.4 1.1 6.7 6 2 0 6 6 6 0 Anaphase-promoting complex APC subunit 1 WD40 PF00400.27 CDJ69013.1 - 3e-13 49.0 3.2 1.3e-06 28.0 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat CDK2AP PF09806.4 CDJ69013.1 - 0.79 9.9 10.2 3.5 7.8 0.6 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF4647 PF15504.1 CDJ69014.1 - 1.2 7.9 16.9 1.5 7.5 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Na_trans_assoc PF06512.8 CDJ69014.1 - 2.5 7.9 9.8 3.6 7.4 6.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated TFIIA PF03153.8 CDJ69014.1 - 3.1 7.5 21.4 4 7.2 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4207 PF13904.1 CDJ69014.1 - 5.6 6.2 31.0 0.92 8.8 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Npa1 PF11707.3 CDJ69016.1 - 0.91 8.4 0.0 2.1 7.2 0.0 1.5 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal HHH_8 PF14716.1 CDJ69017.1 - 0.0074 16.4 0.0 0.41 10.8 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain Mannosyl_trans PF05007.8 CDJ69022.1 - 1.7e-34 119.6 36.4 1.2e-24 87.3 7.1 4.1 2 1 1 3 3 3 3 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 CDJ69022.1 - 4.2e-06 26.4 2.5 4.2e-06 26.4 1.7 3.0 2 2 1 3 3 3 1 Protein of unknown function (DUF2029) Ammonium_transp PF00909.16 CDJ69022.1 - 0.037 12.5 4.8 0.29 9.5 0.4 2.3 2 0 0 2 2 2 0 Ammonium Transporter Family ALG3 PF05208.8 CDJ69022.1 - 0.044 13.0 0.2 0.044 13.0 0.2 3.6 3 1 0 3 3 3 0 ALG3 protein Myosin_head PF00063.16 CDJ69023.1 - 6.6e-28 97.1 0.0 4e-24 84.6 0.0 3.2 2 1 0 2 2 2 2 Myosin head (motor domain) BTB PF00651.26 CDJ69024.1 - 3.2e-06 27.0 0.0 7.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain FPL PF09758.4 CDJ69025.1 - 2.2e-44 150.8 1.0 3.9e-44 150.0 0.7 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein SWIB PF02201.13 CDJ69026.1 - 8.9e-20 70.1 0.1 1.5e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF3043 PF11241.3 CDJ69026.1 - 0.088 12.3 1.1 0.13 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PXA PF02194.10 CDJ69026.1 - 0.53 9.8 3.8 0.85 9.1 2.6 1.2 1 0 0 1 1 1 0 PXA domain RAP1 PF07218.6 CDJ69026.1 - 2.6 6.0 15.4 3.3 5.6 6.6 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) ubiquitin PF00240.18 CDJ69027.1 - 3.5e-09 35.9 0.0 1e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CDJ69027.1 - 6.6e-08 32.1 0.1 2e-07 30.6 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 CDJ69027.1 - 0.0057 16.3 0.0 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 CDJ69027.1 - 0.012 15.0 0.0 0.14 11.6 0.0 2.5 2 0 0 2 2 2 0 CUE domain PAP2 PF01569.16 CDJ69027.1 - 0.029 14.0 0.3 0.74 9.4 0.0 2.6 2 1 0 2 2 2 0 PAP2 superfamily Fucose_iso_N1 PF07881.7 CDJ69027.1 - 0.23 10.9 3.2 0.98 8.9 0.3 2.8 2 1 0 2 2 2 0 L-fucose isomerase, first N-terminal domain Chromo PF00385.19 CDJ69028.1 - 0.00032 20.2 0.3 0.00076 19.1 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TFIIS_M PF07500.9 CDJ69029.1 - 7e-09 35.7 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Peptidase_S49_N PF08496.5 CDJ69030.1 - 0.14 11.9 2.9 0.21 11.3 2.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Uds1 PF15456.1 CDJ69030.1 - 0.65 10.0 10.7 1.7 8.6 7.4 1.8 1 1 0 1 1 1 0 Up-regulated During Septation TSA PF03249.8 CDJ69030.1 - 3.2 6.1 5.9 4.7 5.6 4.1 1.3 1 0 0 1 1 1 0 Type specific antigen Coprogen_oxidas PF01218.13 CDJ69032.1 - 2.2e-11 42.8 0.7 7.6e-11 41.0 0.5 1.7 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase LCCL PF03815.14 CDJ69032.1 - 0.018 14.9 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 LCCL domain DUF853 PF05872.7 CDJ69032.1 - 0.022 13.1 0.4 0.024 13.0 0.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2890 PF11081.3 CDJ69032.1 - 0.035 14.1 1.3 0.046 13.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ilar_coat PF01787.11 CDJ69032.1 - 0.056 13.0 0.1 0.074 12.6 0.1 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein APC_CDC26 PF10471.4 CDJ69032.1 - 0.27 12.0 4.4 0.46 11.2 3.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 KfrA_N PF11740.3 CDJ69032.1 - 7.1 7.1 12.5 2 8.9 6.6 1.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Coprogen_oxidas PF01218.13 CDJ69033.1 - 1.3e-61 207.7 1.1 2.8e-60 203.4 0.5 2.5 2 1 0 2 2 2 2 Coproporphyrinogen III oxidase Spt20 PF12090.3 CDJ69036.1 - 0.77 9.0 10.3 3.4 6.9 0.3 3.1 3 0 0 3 3 3 0 Spt20 family IMS_C PF11799.3 CDJ69038.1 - 0.0069 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.15 CDJ69038.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 impB/mucB/samB family ADH_zinc_N PF00107.21 CDJ69040.1 - 1.7e-18 66.4 0.1 3.3e-18 65.5 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDJ69040.1 - 0.0014 19.5 0.0 0.0026 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 CDJ69040.1 - 0.13 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PCI PF01399.22 CDJ69041.1 - 0.016 15.5 0.0 0.74 10.1 0.0 2.3 2 0 0 2 2 2 0 PCI domain Exo_endo_phos PF03372.18 CDJ69043.1 - 6.2e-18 65.6 1.2 1e-16 61.6 0.1 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Adaptin_binding PF10199.4 CDJ69044.1 - 0.59 10.4 20.0 0.21 11.8 4.3 3.6 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Gti1_Pac2 PF09729.4 CDJ69044.1 - 1.8 8.4 10.1 29 4.4 6.2 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family Suf PF05843.9 CDJ69044.1 - 3.3 7.3 20.5 0.027 14.2 6.6 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Dehydrin PF00257.14 CDJ69045.1 - 0.0077 16.5 6.1 0.0077 16.5 4.2 10.2 5 2 0 5 5 5 1 Dehydrin Galactosyl_T PF01762.16 CDJ69046.1 - 1.1e-31 109.9 0.0 1.7e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Med15 PF09606.5 CDJ69046.1 - 0.0012 17.1 11.4 0.0012 17.1 7.9 2.3 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4131 PF13567.1 CDJ69046.1 - 0.0075 15.6 1.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) GRP PF07172.6 CDJ69046.1 - 0.18 12.2 0.0 0.64 10.5 0.0 1.9 1 0 0 1 1 1 0 Glycine rich protein family TMEM154 PF15102.1 CDJ69046.1 - 0.55 9.9 0.0 0.55 9.9 0.0 2.3 3 0 0 3 3 3 0 TMEM154 protein family Med15 PF09606.5 CDJ69048.1 - 0.00019 19.8 63.1 0.00019 19.8 43.8 4.2 3 1 0 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal Tme5_EGF_like PF09064.5 CDJ69048.1 - 0.00041 19.9 3.1 4.9 6.8 0.3 6.0 6 0 0 6 6 6 1 Thrombomodulin like fifth domain, EGF-like CBM_14 PF01607.19 CDJ69048.1 - 1.1 9.2 0.0 1.1 9.2 0.0 6.1 5 2 2 7 7 7 0 Chitin binding Peritrophin-A domain SpoIIE PF07228.7 CDJ69049.1 - 3.9e-08 33.2 1.0 2.2e-07 30.7 0.7 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CDJ69049.1 - 2.1e-07 30.5 0.0 1.1e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CDJ69049.1 - 0.00011 21.7 0.2 0.00028 20.3 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DEC-1_N PF04625.8 CDJ69049.1 - 2 7.0 9.8 0.13 10.8 2.9 1.9 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Rep_fac-A_C PF08646.5 CDJ69050.1 - 1.3e-28 99.5 0.0 1.9e-22 79.5 0.0 3.2 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CDJ69050.1 - 4e-14 52.2 0.1 1.5e-10 40.7 0.0 3.3 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF4503 PF14951.1 CDJ69050.1 - 0.00051 18.3 0.3 0.0011 17.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4503) Cyclin_C PF02984.14 CDJ69052.1 - 0.25 11.2 2.2 0.77 9.6 0.2 2.6 2 0 0 2 2 2 0 Cyclin, C-terminal domain Spc7 PF08317.6 CDJ69052.1 - 0.26 9.9 18.9 0.44 9.1 4.8 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CDJ69052.1 - 0.53 9.3 5.6 4.2 6.4 0.2 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein SprA-related PF12118.3 CDJ69053.1 - 0.0013 18.1 29.6 0.0016 17.8 20.5 1.0 1 0 0 1 1 1 1 SprA-related family Raftlin PF15250.1 CDJ69053.1 - 0.0025 16.4 12.5 0.0027 16.2 8.7 1.2 1 0 0 1 1 1 1 Raftlin FLO_LFY PF01698.11 CDJ69053.1 - 0.0043 15.9 8.4 0.0049 15.7 5.8 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein FimP PF09766.4 CDJ69053.1 - 0.0053 15.8 13.0 0.0066 15.5 9.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein Med15 PF09606.5 CDJ69053.1 - 0.0091 14.2 35.1 0.011 14.0 24.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ69053.1 - 0.0093 15.7 9.7 0.01 15.5 6.7 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) AAA_23 PF13476.1 CDJ69053.1 - 0.012 15.9 3.5 0.012 15.8 2.5 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 CDJ69053.1 - 0.015 15.1 7.9 0.018 14.9 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDJ69053.1 - 0.039 13.4 12.6 0.049 13.0 8.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF1800 PF08811.6 CDJ69053.1 - 0.053 12.4 5.9 0.053 12.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) BAAT_C PF08840.6 CDJ69053.1 - 0.054 13.2 3.7 0.071 12.7 2.6 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Presenilin PF01080.12 CDJ69053.1 - 0.081 11.7 10.6 0.1 11.3 7.3 1.1 1 0 0 1 1 1 0 Presenilin Peroxin-13_N PF04088.8 CDJ69053.1 - 0.083 12.8 1.0 0.11 12.4 0.7 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region PAT1 PF09770.4 CDJ69053.1 - 0.13 10.5 21.9 0.15 10.3 15.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hex_IIIa PF02455.11 CDJ69053.1 - 0.21 10.2 7.3 0.26 9.9 5.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Cellulose_synt PF03552.9 CDJ69053.1 - 0.33 9.1 10.3 0.41 8.8 7.2 1.1 1 0 0 1 1 1 0 Cellulose synthase eIF-3_zeta PF05091.7 CDJ69053.1 - 0.38 9.3 11.0 0.37 9.3 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LMBR1 PF04791.11 CDJ69053.1 - 0.41 9.1 2.9 0.43 9.1 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Herpes_UL87 PF03043.9 CDJ69053.1 - 0.41 8.9 10.0 0.48 8.7 6.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Folate_carrier PF01770.13 CDJ69053.1 - 0.53 8.7 6.7 0.66 8.4 4.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier PBP1_TM PF14812.1 CDJ69053.1 - 0.73 10.1 4.7 1.3 9.4 3.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glt_symporter PF03616.9 CDJ69053.1 - 1 7.7 2.7 1.3 7.4 1.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter FHIPEP PF00771.15 CDJ69053.1 - 1.2 7.3 5.5 1.5 7.0 3.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3043 PF11241.3 CDJ69053.1 - 1.3 8.6 9.2 1.9 8.0 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4106 PF13388.1 CDJ69053.1 - 1.3 7.8 18.1 1.6 7.6 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF605 PF04652.11 CDJ69053.1 - 1.7 7.9 17.8 2.1 7.6 12.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF912 PF06024.7 CDJ69053.1 - 2.1 8.4 9.9 0.8 9.7 4.6 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TFIIA PF03153.8 CDJ69053.1 - 2.4 7.9 23.7 3 7.6 16.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 CDJ69053.1 - 2.7 6.8 11.1 3 6.7 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HCO3_cotransp PF00955.16 CDJ69053.1 - 3.2 6.2 5.0 3.9 6.0 3.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF2347 PF09804.4 CDJ69053.1 - 3.3 6.9 7.1 4.4 6.4 4.9 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DDRGK PF09756.4 CDJ69053.1 - 3.4 7.0 17.1 4.5 6.6 11.9 1.1 1 0 0 1 1 1 0 DDRGK domain Peptidase_S49_N PF08496.5 CDJ69053.1 - 4.2 7.1 9.4 5.7 6.7 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Hid1 PF12722.2 CDJ69053.1 - 4.7 4.7 13.5 5.9 4.4 9.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Transposase_21 PF02992.9 CDJ69053.1 - 7.5 5.5 10.0 9.6 5.2 6.9 1.1 1 0 0 1 1 1 0 Transposase family tnp2 zf-MYND PF01753.13 CDJ69054.1 - 0.015 15.1 9.5 0.025 14.4 6.6 1.4 1 0 0 1 1 1 0 MYND finger DUF605 PF04652.11 CDJ69054.1 - 3.4 6.9 36.2 0.024 14.0 8.0 2.2 2 0 0 2 2 2 0 Vta1 like WD40 PF00400.27 CDJ69055.1 - 3.5e-14 52.0 16.7 5.2e-06 26.1 0.0 7.1 6 1 0 6 6 6 4 WD domain, G-beta repeat PAT1 PF09770.4 CDJ69056.1 - 0.032 12.4 123.0 0.15 10.3 25.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDJ69056.1 - 9.1 4.2 54.4 0.79 7.8 23.6 2.1 2 0 0 2 2 2 0 Utp14 protein Ras PF00071.17 CDJ69057.1 - 1.1e-32 112.6 0.1 1.2e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ69057.1 - 3.6e-10 40.3 0.0 4.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDJ69057.1 - 4.6e-08 32.4 0.0 5.1e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CDJ69057.1 - 0.00019 21.3 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 CDJ69057.1 - 0.0067 16.0 0.0 0.0077 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDJ69057.1 - 0.038 14.1 0.0 0.039 14.1 0.0 1.2 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 CDJ69057.1 - 0.039 13.3 0.0 0.37 10.1 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CDJ69057.1 - 0.053 12.6 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DAP3 PF10236.4 CDJ69057.1 - 0.075 11.9 0.0 0.099 11.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF258 PF03193.11 CDJ69057.1 - 0.084 12.0 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CDJ69057.1 - 0.095 12.2 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Med3 PF11593.3 CDJ69059.1 - 0.00025 20.4 10.1 0.00036 19.8 7.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF1049 PF06305.6 CDJ69059.1 - 0.033 13.6 0.2 0.11 12.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2840 PF11000.3 CDJ69059.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) Herpes_LMP2 PF07415.6 CDJ69060.1 - 0.038 12.5 3.9 0.048 12.2 2.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein zf-DHHC PF01529.15 CDJ69060.1 - 0.1 12.0 1.4 0.17 11.2 1.0 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase TFIIA PF03153.8 CDJ69060.1 - 0.11 12.3 13.3 0.13 12.1 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDJ69060.1 - 0.32 9.1 30.4 0.41 8.7 21.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ69060.1 - 0.33 9.1 24.6 0.4 8.8 17.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FCP1_C PF09309.5 CDJ69060.1 - 0.45 9.7 10.6 0.75 9.0 7.4 1.4 1 0 0 1 1 1 0 FCP1, C-terminal Neur_chan_memb PF02932.11 CDJ69060.1 - 0.74 9.6 6.4 0.86 9.4 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Plasmodium_Vir PF05795.6 CDJ69060.1 - 1.1 8.3 4.2 1.4 8.0 2.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.12 CDJ69060.1 - 1.4 7.6 6.5 1.7 7.4 4.5 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.7 CDJ69060.1 - 1.9 7.0 10.9 2.2 6.8 7.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Macoilin PF09726.4 CDJ69060.1 - 2.2 6.4 15.0 2.6 6.2 10.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF853 PF05872.7 CDJ69060.1 - 2.3 6.4 6.2 2.9 6.1 4.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Hid1 PF12722.2 CDJ69060.1 - 2.9 5.4 9.7 3.2 5.3 6.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDJ69060.1 - 2.9 6.2 9.7 3.4 5.9 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex16 PF08610.5 CDJ69060.1 - 7.9 5.3 13.0 10 5.0 9.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Herpes_DNAp_acc PF04929.7 CDJ69060.1 - 8.3 5.2 12.6 11 4.9 8.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RAP1 PF07218.6 CDJ69060.1 - 9.1 4.2 11.7 11 4.0 8.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RimM PF01782.13 CDJ69063.1 - 5e-10 39.1 0.0 5e-10 39.1 0.0 2.5 3 0 0 3 3 3 1 RimM N-terminal domain SseC PF04888.7 CDJ69063.1 - 0.00042 19.7 16.9 0.00042 19.7 11.7 7.1 7 1 0 7 7 7 1 Secretion system effector C (SseC) like family DUF966 PF06136.8 CDJ69063.1 - 6.7 6.0 45.7 0.12 11.7 3.8 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF966) Spo7_2_N PF15407.1 CDJ69064.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Sporulation protein family 7 Ribosomal_60s PF00428.14 CDJ69064.1 - 0.017 15.4 5.1 0.017 15.4 3.5 2.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein HemX PF04375.9 CDJ69064.1 - 0.031 12.8 18.9 0.012 14.2 10.4 1.9 2 0 0 2 2 2 0 HemX Shadoo PF14999.1 CDJ69064.1 - 0.032 14.0 21.3 0.2 11.4 5.9 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective MASE1 PF05231.9 CDJ69064.1 - 0.048 12.6 1.1 0.07 12.1 0.7 1.3 1 0 0 1 1 1 0 MASE1 DUF4367 PF14285.1 CDJ69064.1 - 0.072 12.3 2.7 0.71 9.1 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Med15 PF09606.5 CDJ69064.1 - 0.22 9.7 23.6 0.28 9.3 16.4 1.2 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_M17_N PF02789.12 CDJ69064.1 - 0.32 10.7 6.9 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain AP_endonuc_2 PF01261.19 CDJ69064.1 - 0.61 9.3 2.8 1.2 8.3 1.1 1.8 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel PWI PF01480.12 CDJ69065.1 - 1.6e-12 47.3 0.7 1.6e-12 47.3 0.5 2.0 2 0 0 2 2 2 1 PWI domain RAP1 PF07218.6 CDJ69065.1 - 0.00026 19.2 10.0 0.00031 19.0 7.0 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Pol_alpha_B_N PF08418.5 CDJ69065.1 - 0.0099 15.4 16.6 0.015 14.8 11.5 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Daxx PF03344.10 CDJ69065.1 - 0.017 13.6 21.6 0.019 13.4 15.0 1.1 1 0 0 1 1 1 0 Daxx Family Peptidase_S64 PF08192.6 CDJ69065.1 - 0.019 13.2 12.1 0.021 13.1 8.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.13 CDJ69065.1 - 0.41 8.8 4.2 0.46 8.7 2.9 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF572 PF04502.8 CDJ69065.1 - 1.2 8.3 27.3 1.5 7.9 18.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2413 PF10310.4 CDJ69065.1 - 1.8 7.3 24.2 2.4 6.8 16.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DNA_pol_viral_N PF00242.12 CDJ69065.1 - 3.4 6.5 20.4 4.7 6.1 14.1 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Hid1 PF12722.2 CDJ69065.1 - 3.7 5.0 20.5 4.5 4.8 14.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SRP-alpha_N PF04086.8 CDJ69065.1 - 3.8 6.8 26.5 5.3 6.3 18.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AvrE PF11725.3 CDJ69065.1 - 5.4 3.9 25.3 6.5 3.6 17.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor TMEM51 PF15345.1 CDJ69065.1 - 5.9 6.5 23.9 8.9 5.9 16.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Rad17 PF03215.10 CDJ69066.1 - 3.1e-09 36.0 0.0 2e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CDJ69066.1 - 0.057 13.1 0.5 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CDJ69066.1 - 0.74 10.0 2.9 1.6 8.9 0.1 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) LRR_4 PF12799.2 CDJ69067.1 - 6e-11 41.7 3.1 2e-07 30.4 0.4 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDJ69067.1 - 2e-06 27.0 0.8 0.4 10.8 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.1 CDJ69067.1 - 7.2e-06 25.6 2.0 0.00091 18.9 0.2 2.2 2 0 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 CDJ69067.1 - 0.00026 20.7 0.5 7 7.3 0.0 3.5 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 CDJ69067.1 - 0.0014 18.4 1.5 2.3 8.5 0.0 3.3 2 1 1 3 3 3 1 Leucine Rich repeat LRR_9 PF14580.1 CDJ69067.1 - 0.032 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat SPOUT_MTase PF02590.12 CDJ69067.1 - 0.054 13.2 2.9 0.1 12.3 2.0 1.5 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase LRR_3 PF07725.7 CDJ69067.1 - 0.097 12.4 0.6 19 5.2 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich Repeat Abhydrolase_5 PF12695.2 CDJ69067.1 - 0.21 11.3 8.4 0.38 10.5 5.6 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Band_3_cyto PF07565.8 CDJ69067.1 - 0.39 10.1 16.2 0.69 9.3 6.0 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PLRV_ORF5 PF01690.12 CDJ69067.1 - 1.1 8.3 25.8 1.5 7.9 17.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein EMG1 PF03587.9 CDJ69067.1 - 1.1 8.4 5.6 6.3 6.0 0.8 2.4 1 1 1 2 2 2 0 EMG1/NEP1 methyltransferase V_ATPase_I PF01496.14 CDJ69067.1 - 2.5 5.8 6.3 4.7 4.9 4.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.1 CDJ69067.1 - 3.7 7.2 23.5 0.36 10.5 2.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A RAP1 PF07218.6 CDJ69067.1 - 6 4.8 19.0 11 4.0 13.2 1.5 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) rRNA_proc-arch PF13234.1 CDJ69068.1 - 8.4e-53 179.2 0.0 1.4e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 CDJ69068.1 - 1.9e-07 30.8 1.1 5.5e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Tryp_alpha_amyl PF00234.17 CDJ69068.1 - 2.5 8.3 8.9 0.84 9.8 2.9 2.5 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family TPR_11 PF13414.1 CDJ69069.1 - 1.2e-07 31.2 1.0 1.2e-07 31.2 0.7 2.6 1 1 1 2 2 2 1 TPR repeat TPR_14 PF13428.1 CDJ69069.1 - 0.00046 20.5 10.4 0.0067 16.9 4.5 5.6 3 2 3 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ69069.1 - 0.0015 19.1 9.8 0.0015 19.1 6.8 4.9 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ69069.1 - 0.0018 18.0 14.5 0.0048 16.7 1.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF4647 PF15504.1 CDJ69069.1 - 0.0037 16.1 12.1 0.0047 15.8 8.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) TPR_1 PF00515.23 CDJ69069.1 - 0.022 14.3 4.4 0.37 10.4 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2217 PF10265.4 CDJ69069.1 - 0.043 12.5 8.6 0.052 12.3 6.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Cwf_Cwc_15 PF04889.7 CDJ69069.1 - 0.047 13.4 11.2 0.077 12.6 7.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_17 PF13431.1 CDJ69069.1 - 0.058 13.6 0.0 0.058 13.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PLRV_ORF5 PF01690.12 CDJ69069.1 - 0.27 10.3 10.8 0.32 10.0 7.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TFIIA PF03153.8 CDJ69069.1 - 0.44 10.3 24.3 0.71 9.7 16.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 CDJ69069.1 - 1 8.7 25.8 2.2 7.6 17.9 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CDJ69069.1 - 1.4 7.0 13.8 1.8 6.7 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein NST1 PF13945.1 CDJ69069.1 - 1.5 8.8 19.5 2.3 8.2 13.5 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator FAM60A PF15396.1 CDJ69069.1 - 1.6 8.4 10.8 2.2 7.9 7.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A RskA PF10099.4 CDJ69069.1 - 2 8.0 33.8 0.057 13.1 2.7 3.2 3 0 0 3 3 3 0 Anti-sigma-K factor rskA CAML PF14963.1 CDJ69069.1 - 2.4 7.4 6.4 3.4 6.9 4.4 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand SAGA-Tad1 PF12767.2 CDJ69069.1 - 2.5 7.7 16.3 3.5 7.2 11.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SAE2 PF08573.5 CDJ69069.1 - 2.8 8.6 7.4 1.5 9.5 2.0 2.3 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Dehydrin PF00257.14 CDJ69069.1 - 3 8.1 17.5 0.44 10.8 6.6 2.2 2 0 0 2 2 2 0 Dehydrin APC_CDC26 PF10471.4 CDJ69069.1 - 3.3 8.5 30.9 3.1 8.5 3.7 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Hid1 PF12722.2 CDJ69069.1 - 3.3 5.2 15.9 4.3 4.9 11.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.6 CDJ69069.1 - 4.2 5.5 13.5 4.9 5.3 9.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.4 CDJ69069.1 - 4.5 5.3 31.0 6 4.9 21.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF755 PF05501.6 CDJ69069.1 - 6.8 6.7 29.8 0.3 11.1 12.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) U79_P34 PF03064.11 CDJ69070.1 - 0.055 12.9 17.3 0.09 12.2 12.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PAT1 PF09770.4 CDJ69070.1 - 0.056 11.6 46.1 0.059 11.6 31.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ69070.1 - 0.083 11.0 66.9 0.11 10.6 46.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC27 PF09507.5 CDJ69070.1 - 0.17 11.0 30.3 0.22 10.7 21.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Neur_chan_memb PF02932.11 CDJ69070.1 - 2.9 7.7 14.9 3.7 7.3 10.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDJ69070.1 - 9.2 3.7 26.2 10 3.6 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med15 PF09606.5 CDJ69071.1 - 2.2e-06 26.1 88.3 9.5e-06 24.1 29.3 5.9 6 0 0 6 6 6 4 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDJ69071.1 - 0.0029 17.1 1.1 0.0029 17.1 0.8 11.7 10 2 1 11 11 11 3 Nuclear RNA-splicing-associated protein RrnaAD PF00398.15 CDJ69072.1 - 5.3e-16 58.4 0.0 6.6e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Robl_LC7 PF03259.12 CDJ69072.1 - 0.014 14.9 0.8 0.019 14.4 0.1 1.5 2 0 0 2 2 2 0 Roadblock/LC7 domain CAF-1_p150 PF11600.3 CDJ69073.1 - 0.015 14.6 30.1 0.021 14.2 20.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 CDJ69073.1 - 0.066 13.1 14.2 0.069 13.1 9.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family eIF-3_zeta PF05091.7 CDJ69073.1 - 0.15 10.6 15.4 0.15 10.6 10.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TAF1D PF15333.1 CDJ69073.1 - 0.2 11.3 18.4 0.29 10.8 12.8 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D FbpA PF05833.6 CDJ69073.1 - 0.22 10.0 17.5 0.25 9.8 12.1 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SR-25 PF10500.4 CDJ69073.1 - 0.55 9.6 43.3 0.22 10.9 26.7 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.7 CDJ69073.1 - 0.84 9.4 17.0 0.99 9.2 11.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.1 CDJ69073.1 - 0.86 8.0 15.9 0.9 7.9 11.0 1.1 1 0 0 1 1 1 0 Raftlin DUF1675 PF07897.6 CDJ69073.1 - 1.1 9.0 22.8 1.2 8.8 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SOBP PF15279.1 CDJ69073.1 - 1.4 9.2 20.7 1.6 9.0 14.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_23 PF13476.1 CDJ69073.1 - 2.4 8.4 16.1 2.7 8.2 11.2 1.1 1 0 0 1 1 1 0 AAA domain TraT PF05818.7 CDJ69073.1 - 3.2 7.0 19.4 0.077 12.4 4.8 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Med15 PF09606.5 CDJ69073.1 - 3.3 5.7 47.4 4 5.5 32.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_coat_CotO PF14153.1 CDJ69073.1 - 7.4 5.9 26.3 9.7 5.5 18.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Adaptin_N PF01602.15 CDJ69075.1 - 2.4e-45 154.8 8.2 1.6e-44 152.1 1.7 4.3 3 1 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.17 CDJ69075.1 - 0.22 11.7 6.0 13 6.1 0.1 4.4 3 0 0 3 3 3 0 HEAT repeat DUF2973 PF11189.3 CDJ69075.1 - 1.4 8.7 3.5 6.9 6.5 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2973) DUF2722 PF10846.3 CDJ69076.1 - 6.1 5.7 16.2 0.96 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) IncA PF04156.9 CDJ69078.1 - 0.038 13.6 24.2 0.025 14.1 12.3 2.3 2 0 0 2 2 2 0 IncA protein Med15 PF09606.5 CDJ69078.1 - 0.13 10.4 48.1 0.28 9.3 25.6 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDJ69078.1 - 1.3 7.6 10.1 0.16 10.6 4.0 1.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) Trp_oprn_chp PF09534.5 CDJ69078.1 - 1.4 8.5 28.7 4.2 6.9 16.7 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DOR PF14839.1 CDJ69078.1 - 2.4 7.8 24.3 3.4 7.3 0.7 2.4 2 0 0 2 2 2 0 DOR family DUF4557 PF15101.1 CDJ69078.1 - 2.9 7.6 19.5 5.2 6.8 10.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) SecY PF00344.15 CDJ69078.1 - 3.7 6.3 6.7 5.8 5.7 4.7 1.3 1 0 0 1 1 1 0 SecY translocase YppG PF14179.1 CDJ69078.1 - 6.2 7.4 29.6 9.5 6.8 13.3 2.2 2 0 0 2 2 2 0 YppG-like protein 4HBT PF03061.17 CDJ69079.1 - 0.00016 21.7 0.1 0.00016 21.7 0.1 2.1 3 0 0 3 3 3 1 Thioesterase superfamily NifQ PF04891.7 CDJ69079.1 - 0.0022 18.1 1.7 0.036 14.2 0.1 2.3 2 0 0 2 2 2 1 NifQ dTDP_sugar_isom PF00908.12 CDJ69079.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase DUF3678 PF12435.3 CDJ69079.1 - 4.9 6.7 11.8 6.7 6.3 4.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) IncA PF04156.9 CDJ69080.1 - 0.0049 16.4 6.9 0.0049 16.4 4.8 8.0 7 1 0 7 7 7 2 IncA protein SOBP PF15279.1 CDJ69080.1 - 0.005 17.2 14.1 0.005 17.2 9.8 6.3 3 2 1 4 4 4 1 Sine oculis-binding protein DUF3377 PF11857.3 CDJ69080.1 - 0.65 9.6 4.6 2.6 7.7 3.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) HMG_box PF00505.14 CDJ69081.1 - 2.8e-22 78.7 5.1 4.5e-22 78.1 3.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDJ69081.1 - 1.5e-16 60.4 4.6 2.5e-16 59.7 3.2 1.3 1 0 0 1 1 1 1 HMG-box domain KRAB PF01352.22 CDJ69081.1 - 0.038 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 KRAB box HMG_box_5 PF14887.1 CDJ69081.1 - 0.59 9.9 6.9 0.21 11.3 3.0 1.8 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Spt20 PF12090.3 CDJ69082.1 - 1.6 8.0 16.5 2.4 7.4 2.2 3.2 3 0 0 3 3 3 0 Spt20 family SR-25 PF10500.4 CDJ69083.1 - 0.001 18.5 34.7 0.19 11.1 4.9 4.1 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein EphA2_TM PF14575.1 CDJ69083.1 - 0.066 13.6 0.6 0.32 11.4 0.4 2.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tetraspannin PF00335.15 CDJ69083.1 - 0.16 11.2 0.7 1.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Tetraspanin family Suf PF05843.9 CDJ69084.1 - 0.0064 16.2 8.9 0.0064 16.2 6.2 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ69084.1 - 0.0086 15.1 13.6 0.0086 15.1 9.4 1.0 1 0 0 1 1 1 1 Fms-interacting protein Spt20 PF12090.3 CDJ69084.1 - 0.025 13.9 7.9 0.032 13.5 5.5 1.3 1 0 0 1 1 1 0 Spt20 family SprA-related PF12118.3 CDJ69084.1 - 0.03 13.6 18.4 0.029 13.7 12.7 1.1 1 0 0 1 1 1 0 SprA-related family Peptidase_S49_N PF08496.5 CDJ69084.1 - 0.031 14.0 3.9 0.032 14.0 2.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AIF_C PF14721.1 CDJ69084.1 - 0.031 14.4 1.5 0.033 14.4 1.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zn_peptidase PF04228.8 CDJ69084.1 - 0.06 12.5 5.5 0.065 12.4 3.8 1.0 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF912 PF06024.7 CDJ69084.1 - 0.068 13.2 2.0 0.073 13.1 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1071 PF06378.6 CDJ69084.1 - 0.081 12.0 7.1 0.098 11.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) DUF533 PF04391.7 CDJ69084.1 - 0.09 12.1 8.5 0.087 12.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF3474 PF11960.3 CDJ69084.1 - 0.12 12.3 0.3 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Med15 PF09606.5 CDJ69084.1 - 0.13 10.4 30.9 0.11 10.6 21.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.12 CDJ69084.1 - 0.24 11.1 3.8 0.24 11.1 2.7 1.1 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDJ69084.1 - 0.36 9.4 5.5 0.35 9.5 3.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex16 PF08610.5 CDJ69084.1 - 0.38 9.6 8.6 0.41 9.6 6.0 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3801 PF12687.2 CDJ69084.1 - 0.43 10.1 9.4 0.42 10.1 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) zf-DHHC PF01529.15 CDJ69084.1 - 0.46 9.8 2.9 0.43 9.9 2.0 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Band_3_cyto PF07565.8 CDJ69084.1 - 0.49 9.8 6.3 0.5 9.8 4.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Folate_carrier PF01770.13 CDJ69084.1 - 0.76 8.2 3.5 0.83 8.1 2.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF3043 PF11241.3 CDJ69084.1 - 1.3 8.5 5.0 1.4 8.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PH_4 PF15404.1 CDJ69084.1 - 1.4 8.4 8.0 1.7 8.1 5.6 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF788 PF05620.6 CDJ69084.1 - 1.5 8.6 8.8 1.8 8.4 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) EIIBC-GUT_N PF03612.9 CDJ69084.1 - 1.5 8.4 6.5 1.8 8.1 4.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ctr PF04145.10 CDJ69084.1 - 1.6 8.7 4.1 1.8 8.6 2.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family RR_TM4-6 PF06459.7 CDJ69084.1 - 1.7 8.4 8.1 2.1 8.1 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4175 PF13779.1 CDJ69084.1 - 1.9 6.1 28.9 2.1 5.9 20.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.1 CDJ69084.1 - 1.9 7.3 10.6 2 7.3 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pex14_N PF04695.8 CDJ69084.1 - 2.2 8.3 18.1 2.8 8.0 12.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SHR3_chaperone PF08229.6 CDJ69084.1 - 3.5 6.5 11.3 4.1 6.3 7.8 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Glyco_transf_15 PF01793.11 CDJ69084.1 - 3.6 6.4 7.4 3.9 6.3 5.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF4557 PF15101.1 CDJ69084.1 - 3.8 7.2 19.6 4.3 7.1 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) OATP PF03137.15 CDJ69084.1 - 4 5.3 8.0 4.2 5.2 5.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family IncA PF04156.9 CDJ69084.1 - 4.9 6.6 17.8 5.4 6.5 12.3 1.1 1 0 0 1 1 1 0 IncA protein BRF1 PF07741.8 CDJ69084.1 - 5.6 7.2 12.0 7 6.9 8.3 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain TMEM51 PF15345.1 CDJ69084.1 - 5.9 6.5 11.2 6.7 6.3 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Gag_spuma PF03276.9 CDJ69084.1 - 7.5 4.7 20.1 8.2 4.6 14.0 1.0 1 0 0 1 1 1 0 Spumavirus gag protein G0-G1_switch_2 PF15103.1 CDJ69084.1 - 8.1 6.7 9.0 9.6 6.4 6.2 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 AAA_22 PF13401.1 CDJ69085.1 - 1.7e-07 31.3 0.0 6.4e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDJ69085.1 - 0.0031 16.7 0.1 0.008 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 CDJ69085.1 - 0.058 13.0 4.2 0.32 10.6 2.9 2.2 1 1 0 1 1 1 0 NACHT domain AAA PF00004.24 CDJ69085.1 - 0.072 13.2 0.0 0.072 13.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HSP20 PF00011.16 CDJ69086.1 - 3.8e-12 45.9 0.0 6.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ACBP PF00887.14 CDJ69089.1 - 2.5e-28 97.5 1.6 2.8e-28 97.4 1.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein BTB_2 PF02214.17 CDJ69090.1 - 8e-05 22.7 0.0 0.00025 21.1 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain SAPS PF04499.10 CDJ69090.1 - 1.2 7.6 24.2 0.026 13.1 3.5 3.3 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein Herpes_UL87 PF03043.9 CDJ69090.1 - 5.3 5.3 12.6 0.65 8.3 0.0 3.0 3 1 0 3 3 3 0 Herpesvirus UL87 family Methyltrn_RNA_3 PF02598.12 CDJ69091.1 - 1.3e-47 162.5 0.6 3.4e-22 79.1 0.0 4.8 4 1 1 5 5 4 4 Putative RNA methyltransferase Med15 PF09606.5 CDJ69091.1 - 0.00058 18.2 19.9 0.00085 17.6 13.8 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 CDJ69091.1 - 0.014 15.4 0.2 0.077 13.0 0.1 2.0 2 0 0 2 2 2 0 Ctr copper transporter family DUF4557 PF15101.1 CDJ69091.1 - 0.023 14.5 12.0 0.041 13.7 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2514 PF10721.4 CDJ69091.1 - 0.05 13.3 12.9 0.11 12.1 8.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) SpoVR PF04293.8 CDJ69091.1 - 0.12 10.7 7.4 0.18 10.1 5.1 1.2 1 0 0 1 1 1 0 SpoVR like protein DDHD PF02862.12 CDJ69091.1 - 0.22 11.2 7.1 0.77 9.5 4.0 1.9 2 0 0 2 2 2 0 DDHD domain Serinc PF03348.10 CDJ69091.1 - 0.3 9.7 4.7 0.48 9.0 3.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3260 PF11658.3 CDJ69091.1 - 0.54 8.3 6.1 0.76 7.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF1266 PF06889.6 CDJ69091.1 - 0.9 9.3 7.2 1.8 8.3 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) FAM176 PF14851.1 CDJ69091.1 - 0.92 9.1 6.2 0.5 10.0 2.2 1.9 2 0 0 2 2 2 0 FAM176 family SprA-related PF12118.3 CDJ69091.1 - 1.1 8.5 24.9 0.16 11.2 14.1 1.7 2 0 0 2 2 2 0 SprA-related family Hid1 PF12722.2 CDJ69091.1 - 1.5 6.3 6.7 2.3 5.7 4.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIF_C PF14721.1 CDJ69091.1 - 1.5 9.0 7.9 0.2 11.8 2.2 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Spt20 PF12090.3 CDJ69091.1 - 2 7.7 10.8 0.46 9.8 4.9 1.8 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.8 CDJ69091.1 - 2.1 8.4 14.4 4.5 7.3 9.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDJ69091.1 - 2.4 7.7 14.4 4.3 6.9 10.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MMR1 PF08505.5 CDJ69091.1 - 3.2 7.7 16.4 0.15 12.0 7.2 1.7 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Pex16 PF08610.5 CDJ69091.1 - 3.5 6.5 9.2 6 5.7 6.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) POX PF07526.6 CDJ69091.1 - 3.7 7.7 14.5 1 9.5 6.9 1.9 2 0 0 2 2 2 0 Associated with HOX FimP PF09766.4 CDJ69091.1 - 5 6.0 21.8 0.054 12.5 9.9 1.4 2 0 0 2 2 1 0 Fms-interacting protein Peroxin-13_N PF04088.8 CDJ69091.1 - 5.3 6.9 8.1 0.2 11.6 1.4 1.6 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DHHW PF14286.1 CDJ69091.1 - 5.3 6.2 6.4 2.3 7.4 2.8 1.5 2 0 0 2 2 2 0 DHHW protein OATP PF03137.15 CDJ69091.1 - 6.3 4.7 5.5 10 4.0 3.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4175 PF13779.1 CDJ69091.1 - 7.4 4.1 31.3 11 3.5 21.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Rxt3 PF08642.5 CDJ69091.1 - 7.4 6.8 7.1 1 9.6 1.9 1.8 2 0 0 2 2 1 0 Histone deacetylation protein Rxt3 AdoHcyase PF05221.12 CDJ69092.1 - 5.1e-128 425.6 0.0 5.9e-128 425.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CDJ69092.1 - 2.1e-81 271.5 0.8 3e-81 271.0 0.5 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CDJ69092.1 - 2.6e-07 29.9 0.1 4.7e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CDJ69092.1 - 8.5e-05 21.9 0.1 0.00016 21.0 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CDJ69092.1 - 0.0007 19.5 0.2 0.0031 17.5 0.1 2.1 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 CDJ69092.1 - 0.014 15.5 0.3 0.037 14.1 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 CDJ69092.1 - 0.042 12.9 3.2 0.054 12.5 0.2 2.6 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3773 PF12608.3 CDJ69092.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3773) TMEM107 PF14995.1 CDJ69092.1 - 0.13 12.4 3.2 0.51 10.4 2.2 1.8 1 1 0 1 1 1 0 Transmembrane protein MDFI PF15316.1 CDJ69093.1 - 0.016 15.2 8.9 0.016 15.2 6.2 4.0 2 2 3 5 5 5 0 MyoD family inhibitor T2SF PF00482.18 CDJ69093.1 - 0.053 13.4 7.3 6.6 6.6 0.0 4.5 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F Ino80_Iec3 PF14612.1 CDJ69093.1 - 0.49 10.4 15.4 0.16 11.9 7.5 2.1 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling TFIIA PF03153.8 CDJ69094.1 - 2.1 8.1 24.1 1.2 9.0 0.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNase_E_G PF10150.4 CDJ69095.1 - 0.025 13.8 0.8 0.03 13.5 0.5 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family DUF3090 PF11290.3 CDJ69095.1 - 0.036 13.5 1.3 0.05 13.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) ASL_C PF08328.6 CDJ69095.1 - 0.072 12.9 2.3 0.1 12.4 1.6 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal DUF3533 PF12051.3 CDJ69095.1 - 0.68 8.6 2.5 0.81 8.3 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF4557 PF15101.1 CDJ69095.1 - 0.94 9.2 5.0 1.2 8.9 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Cytadhesin_P30 PF07271.6 CDJ69095.1 - 6.4 5.9 11.6 9 5.4 8.1 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 Activator_LAG-3 PF11498.3 CDJ69095.1 - 7.1 5.2 28.8 8.6 4.9 19.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Endonuclease_NS PF01223.18 CDJ69096.1 - 4.2e-05 23.2 0.0 0.00026 20.6 0.0 2.3 2 1 0 2 2 2 1 DNA/RNA non-specific endonuclease DUF2013 PF09431.5 CDJ69097.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) PhnA_Zn_Ribbon PF08274.7 CDJ69097.1 - 0.3 10.8 2.7 0.53 10.1 0.4 2.4 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Peptidase_M14 PF00246.19 CDJ69098.1 - 1.4e-12 47.8 0.1 1.4e-12 47.8 0.1 3.2 3 1 0 3 3 3 1 Zinc carboxypeptidase DUF2722 PF10846.3 CDJ69098.1 - 0.077 12.0 0.1 0.077 12.0 0.1 6.4 5 1 1 6 6 6 0 Protein of unknown function (DUF2722) zf-B_box PF00643.19 CDJ69100.1 - 2.3e-05 24.1 13.4 0.016 15.1 1.6 2.3 2 0 0 2 2 2 2 B-box zinc finger DUF2339 PF10101.4 CDJ69101.1 - 0.64 8.2 14.1 0.34 9.1 3.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) RNase_E_G PF10150.4 CDJ69102.1 - 0.054 12.7 0.2 0.07 12.3 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family 7tm_1 PF00001.16 CDJ69102.1 - 0.11 11.6 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF755 PF05501.6 CDJ69102.1 - 0.16 12.0 5.2 0.24 11.4 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) X PF00739.14 CDJ69102.1 - 0.63 9.9 3.0 1.2 9.0 2.1 1.5 1 0 0 1 1 1 0 Trans-activation protein X Pex14_N PF04695.8 CDJ69104.1 - 0.014 15.4 1.1 0.014 15.4 0.8 3.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDJ69104.1 - 0.053 11.7 11.2 0.076 11.2 7.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mito_fiss_reg PF05308.6 CDJ69104.1 - 6.8 5.9 14.0 0.021 14.2 2.7 1.9 2 1 0 2 2 2 0 Mitochondrial fission regulator PBP1_TM PF14812.1 CDJ69106.1 - 5.9 7.2 11.7 0.48 10.7 0.2 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM60A PF15396.1 CDJ69108.1 - 0.069 12.8 16.8 0.073 12.8 11.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF3357 PF11837.3 CDJ69108.1 - 0.074 12.9 0.2 0.074 12.9 0.1 2.9 1 1 1 2 2 1 0 Domain of unknown function (DUF3357) Spore_coat_CotO PF14153.1 CDJ69108.1 - 0.1 12.0 21.8 0.13 11.6 15.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SAGA-Tad1 PF12767.2 CDJ69108.1 - 0.15 11.6 25.9 0.18 11.4 17.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.9 CDJ69108.1 - 0.18 11.4 24.7 0.23 11.1 17.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SOBP PF15279.1 CDJ69108.1 - 0.26 11.6 20.8 0.27 11.6 14.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.2 CDJ69108.1 - 0.41 8.2 17.8 0.44 8.1 12.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_env PF01673.13 CDJ69108.1 - 1 7.8 10.1 1.1 7.7 7.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein GPCR_chapero_1 PF11904.3 CDJ69108.1 - 1.2 8.2 15.2 1.1 8.2 10.5 1.0 1 0 0 1 1 1 0 GPCR-chaperone DUF913 PF06025.7 CDJ69108.1 - 1.5 7.5 6.5 1.8 7.2 4.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.8 CDJ69108.1 - 1.5 7.2 18.8 1.8 6.9 13.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LMBR1 PF04791.11 CDJ69108.1 - 2 6.9 7.6 2.6 6.5 5.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.9 CDJ69108.1 - 3 5.7 18.0 3.4 5.6 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0139 PF03669.8 CDJ69108.1 - 3.9 7.0 5.8 0.5 9.9 0.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0139) VID27 PF08553.5 CDJ69108.1 - 4.1 5.4 11.4 4.5 5.3 7.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein eIF-3_zeta PF05091.7 CDJ69108.1 - 4.9 5.6 23.6 7.5 5.0 16.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 CDJ69108.1 - 5.6 6.7 18.5 8.1 6.2 12.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF455 PF04305.9 CDJ69108.1 - 8.4 5.5 10.3 12 5.1 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Raftlin PF15250.1 CDJ69108.1 - 9.3 4.6 17.2 12 4.3 11.9 1.1 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.7 CDJ69108.1 - 9.8 6.0 19.7 14 5.5 13.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 CDJ69108.1 - 9.8 3.7 18.3 12 3.5 12.7 1.0 1 0 0 1 1 1 0 Ycf1 Chorion_2 PF03964.10 CDJ69109.1 - 0.0046 17.4 2.5 0.0066 16.9 1.7 1.3 1 0 0 1 1 1 1 Chorion family 2 NLE PF08154.7 CDJ69109.1 - 0.0086 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 NLE (NUC135) domain SR-25 PF10500.4 CDJ69109.1 - 0.014 14.8 13.8 0.017 14.5 9.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC84 PF14968.1 CDJ69109.1 - 0.077 12.4 0.1 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 CAF-1_p150 PF11600.3 CDJ69109.1 - 0.53 9.6 6.5 0.6 9.4 4.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1183 PF06682.7 CDJ69109.1 - 1.2 8.6 4.6 1.4 8.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RAP1 PF07218.6 CDJ69109.1 - 7 4.6 5.8 7.9 4.4 4.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nop25 PF09805.4 CDJ69110.1 - 0.05 13.6 11.3 0.023 14.7 3.5 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) BPD_transp_2 PF02653.11 CDJ69110.1 - 0.12 11.3 2.0 0.092 11.7 0.1 1.8 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component RAP1 PF07218.6 CDJ69110.1 - 0.46 8.5 31.8 0.64 8.0 22.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SelP_N PF04592.9 CDJ69110.1 - 0.54 9.5 20.8 0.22 10.8 10.6 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Pox_E2-like PF04497.7 CDJ69110.1 - 1.6 6.6 4.7 2.1 6.2 3.2 1.1 1 0 0 1 1 1 0 Poxviridae protein Ribosomal_60s PF00428.14 CDJ69110.1 - 2.3 8.6 47.9 2.3 8.6 8.4 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein Herpes_UL20 PF04544.7 CDJ69110.1 - 5.6 6.7 6.2 5.2 6.8 0.2 2.8 3 0 0 3 3 3 0 Herpesvirus egress protein UL20 FAM60A PF15396.1 CDJ69110.1 - 6.9 6.3 25.3 0.86 9.3 12.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A WD40 PF00400.27 CDJ69111.1 - 1.6e-08 34.0 21.3 0.0081 16.0 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CDJ69111.1 - 0.0047 15.1 0.6 0.21 9.6 0.3 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF3446 PF11928.3 CDJ69111.1 - 3.2 8.0 29.1 0.93 9.7 6.8 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) TTL PF03133.10 CDJ69112.1 - 8.3e-05 21.6 0.9 8.3e-05 21.6 0.7 3.2 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family Pkinase PF00069.20 CDJ69113.1 - 4.5e-06 25.9 0.0 8e-06 25.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain TSA PF03249.8 CDJ69113.1 - 6.7 5.1 10.2 9.1 4.6 7.1 1.1 1 0 0 1 1 1 0 Type specific antigen PsbQ PF05757.6 CDJ69114.1 - 6.7 6.0 15.6 3.1 7.1 3.7 2.2 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) GTP1_OBG PF01018.17 CDJ69115.1 - 2.1e-10 40.4 1.1 1.9e-09 37.3 0.7 2.6 1 1 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 CDJ69115.1 - 1.7e-09 37.6 0.0 6.7e-09 35.7 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Caldesmon PF02029.10 CDJ69115.1 - 0.0004 18.9 6.1 0.0004 18.9 4.2 2.3 2 0 0 2 2 2 1 Caldesmon SAPS PF04499.10 CDJ69115.1 - 0.00069 18.3 5.5 0.00069 18.3 3.8 2.2 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein SPX PF03105.14 CDJ69115.1 - 0.0039 17.0 8.0 0.0039 17.0 5.6 2.2 2 0 0 2 2 2 1 SPX domain N6_N4_Mtase PF01555.13 CDJ69115.1 - 0.032 13.7 0.0 4.4 6.7 0.0 2.7 2 1 0 2 2 2 0 DNA methylase Miro PF08477.8 CDJ69115.1 - 0.23 11.9 0.0 0.23 11.9 0.0 3.6 3 1 1 4 4 4 0 Miro-like protein LMBR1 PF04791.11 CDJ69115.1 - 3.5 6.0 20.7 0.17 10.4 1.5 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein CDC45 PF02724.9 CDJ69115.1 - 7.6 4.4 46.0 0.35 8.8 11.2 2.1 2 0 0 2 2 2 0 CDC45-like protein ATP_bind_3 PF01171.15 CDJ69116.1 - 6e-11 42.1 0.0 6e-11 42.1 0.0 2.9 3 1 0 3 3 3 1 PP-loop family Suf PF05843.9 CDJ69116.1 - 0.0036 17.0 1.2 0.0036 17.0 0.8 3.6 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ69116.1 - 0.0094 15.3 21.2 0.33 10.2 0.1 3.3 3 0 0 3 3 3 3 Spt20 family AAA_23 PF13476.1 CDJ69116.1 - 7.4 6.8 23.4 8 6.7 3.6 3.1 3 0 0 3 3 3 0 AAA domain ELO PF01151.13 CDJ69118.1 - 3.1e-38 131.4 8.2 4.3e-38 131.0 5.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3446 PF11928.3 CDJ69119.1 - 0.015 15.5 5.5 0.024 14.8 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Corona_nucleoca PF00937.13 CDJ69119.1 - 0.88 8.4 6.4 1.1 8.1 4.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FSIP1 PF15554.1 CDJ69119.1 - 1.5 7.5 5.8 1.9 7.2 4.0 1.1 1 0 0 1 1 1 0 FSIP1 family PI3_PI4_kinase PF00454.22 CDJ69120.1 - 1.8e-19 70.1 0.0 7.6e-19 68.1 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CDK2AP PF09806.4 CDJ69121.1 - 0.0087 16.3 0.8 0.0087 16.3 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDJ69121.1 - 0.02 15.3 2.4 0.025 14.9 1.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RabGAP-TBC PF00566.13 CDJ69122.1 - 8.3e-40 136.5 0.0 8.3e-40 136.5 0.0 4.5 3 1 2 5 5 5 2 Rab-GTPase-TBC domain Tetraspannin PF00335.15 CDJ69122.1 - 0.62 9.3 0.0 0.62 9.3 0.0 2.6 3 0 0 3 3 3 0 Tetraspanin family Tom22 PF04281.8 CDJ69123.1 - 0.0032 17.0 6.0 0.004 16.6 4.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Suf PF05843.9 CDJ69123.1 - 0.0068 16.1 13.9 0.0074 16.0 9.6 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF3391 PF11871.3 CDJ69123.1 - 0.018 15.2 11.8 0.023 14.9 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3484 PF11983.3 CDJ69123.1 - 0.018 15.8 11.7 0.03 15.1 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) DUF3837 PF12939.2 CDJ69123.1 - 0.021 14.8 0.1 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) FimP PF09766.4 CDJ69123.1 - 0.048 12.7 17.3 0.056 12.4 12.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Pex14_N PF04695.8 CDJ69123.1 - 0.09 12.8 11.6 0.095 12.7 8.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 CDJ69123.1 - 0.1 12.6 4.0 0.13 12.3 2.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tombus_P33 PF08500.5 CDJ69123.1 - 0.1 12.3 2.4 0.13 12.0 1.7 1.1 1 0 0 1 1 1 0 Tombusvirus p33 eIF3g PF12353.3 CDJ69123.1 - 0.11 12.3 6.6 0.18 11.7 4.6 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G TFIIF_beta PF02270.10 CDJ69123.1 - 0.12 12.1 9.2 0.12 12.0 6.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit DUF4175 PF13779.1 CDJ69123.1 - 0.14 9.8 25.9 0.14 9.8 17.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FCP1_C PF09309.5 CDJ69123.1 - 0.14 11.3 10.1 0.15 11.3 7.0 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF3371 PF11851.3 CDJ69123.1 - 0.15 12.7 12.7 0.15 12.7 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Spt20 PF12090.3 CDJ69123.1 - 0.16 11.3 11.0 0.17 11.1 7.6 1.2 1 0 0 1 1 1 0 Spt20 family Ant_C PF05586.6 CDJ69123.1 - 0.16 12.4 2.0 0.19 12.1 1.4 1.1 1 0 0 1 1 1 0 Anthrax receptor C-terminus region PAT1 PF09770.4 CDJ69123.1 - 0.22 9.6 20.7 0.23 9.6 14.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Eapp_C PF10238.4 CDJ69123.1 - 0.23 11.3 6.8 0.25 11.2 4.7 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein Glt_symporter PF03616.9 CDJ69123.1 - 0.27 9.6 3.3 0.3 9.5 2.3 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter Med15 PF09606.5 CDJ69123.1 - 0.28 9.3 29.3 0.24 9.5 20.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_YhcN_YlaJ PF09580.5 CDJ69123.1 - 0.29 11.2 6.7 0.35 10.9 4.7 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF3823 PF12866.2 CDJ69123.1 - 0.33 10.4 4.6 0.37 10.2 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) MRP-S26 PF14943.1 CDJ69123.1 - 0.33 10.4 10.8 0.33 10.5 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 BRF1 PF07741.8 CDJ69123.1 - 0.34 11.1 8.9 0.39 10.9 6.2 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Packaging_FI PF14000.1 CDJ69123.1 - 0.35 11.0 5.6 0.41 10.8 3.8 1.1 1 0 0 1 1 1 0 DNA packaging protein FI Peptidase_S49_N PF08496.5 CDJ69123.1 - 0.4 10.4 6.5 0.39 10.4 4.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ADP_ribosyl_GH PF03747.9 CDJ69123.1 - 0.46 10.2 2.3 0.5 10.0 1.6 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF4557 PF15101.1 CDJ69123.1 - 0.48 10.2 18.1 0.51 10.1 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DivIC PF04977.10 CDJ69123.1 - 0.49 9.9 16.8 0.73 9.3 11.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Spore_coat_CotO PF14153.1 CDJ69123.1 - 0.51 9.7 14.7 0.59 9.5 10.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF775 PF05603.7 CDJ69123.1 - 0.54 9.7 10.9 0.54 9.7 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Paf1 PF03985.8 CDJ69123.1 - 0.54 8.9 9.9 0.51 9.0 6.9 1.0 1 0 0 1 1 1 0 Paf1 EIIBC-GUT_N PF03612.9 CDJ69123.1 - 0.6 9.7 8.3 0.67 9.5 5.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3464 PF11947.3 CDJ69123.1 - 0.71 9.3 6.7 0.78 9.1 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) BAF1_ABF1 PF04684.8 CDJ69123.1 - 0.73 8.6 24.8 0.68 8.7 17.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3499 PF12005.3 CDJ69123.1 - 0.74 10.0 4.7 0.86 9.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) TraH_2 PF06871.6 CDJ69123.1 - 0.75 9.1 3.5 0.84 9.0 2.5 1.1 1 0 0 1 1 1 0 TraH_2 GOLD_2 PF13897.1 CDJ69123.1 - 0.76 10.0 5.5 0.78 9.9 3.8 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking VIT1 PF01988.14 CDJ69123.1 - 0.76 9.2 6.3 0.8 9.1 4.3 1.1 1 0 0 1 1 1 0 VIT family Band_3_cyto PF07565.8 CDJ69123.1 - 0.76 9.2 10.4 0.79 9.1 7.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain zf-DHHC PF01529.15 CDJ69123.1 - 0.78 9.1 8.6 0.96 8.8 6.0 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3154 PF11351.3 CDJ69123.1 - 0.92 9.2 8.2 1.1 8.9 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) TFIIA PF03153.8 CDJ69123.1 - 1.1 9.0 18.7 1.1 9.1 12.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kei1 PF08552.6 CDJ69123.1 - 1.2 8.8 6.7 1.2 8.7 4.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2946 PF11162.3 CDJ69123.1 - 1.3 9.2 5.2 1.4 9.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) AIF_C PF14721.1 CDJ69123.1 - 1.3 9.2 7.5 1.5 9.0 5.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex26 PF07163.7 CDJ69123.1 - 1.4 7.7 10.6 1.4 7.7 7.3 1.0 1 0 0 1 1 1 0 Pex26 protein DUF2324 PF10086.4 CDJ69123.1 - 1.5 8.0 3.7 1.6 7.8 2.6 1.1 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) ADIP PF11559.3 CDJ69123.1 - 1.5 8.7 20.4 1.8 8.4 14.1 1.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1840 PF08895.6 CDJ69123.1 - 1.5 8.9 9.7 1.7 8.7 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) RR_TM4-6 PF06459.7 CDJ69123.1 - 1.5 8.6 9.0 1.5 8.6 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.4 CDJ69123.1 - 1.6 8.6 6.7 1.7 8.5 4.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family OmpH PF03938.9 CDJ69123.1 - 1.6 8.6 24.1 1.9 8.4 16.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3306 PF11748.3 CDJ69123.1 - 1.7 9.2 10.8 1.9 9.1 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DDHD PF02862.12 CDJ69123.1 - 1.7 8.3 7.9 1.8 8.3 5.5 1.1 1 0 0 1 1 1 0 DDHD domain Agouti PF05039.7 CDJ69123.1 - 1.9 8.9 9.2 2.2 8.7 6.4 1.1 1 0 0 1 1 1 0 Agouti protein Zip PF02535.17 CDJ69123.1 - 1.9 7.3 4.2 2.1 7.2 2.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FHIPEP PF00771.15 CDJ69123.1 - 2 6.6 8.1 2.1 6.5 5.6 1.0 1 0 0 1 1 1 0 FHIPEP family DUF4199 PF13858.1 CDJ69123.1 - 2 8.3 6.4 2.2 8.1 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) OATP PF03137.15 CDJ69123.1 - 2.2 6.2 7.4 2.2 6.2 5.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ctr PF04145.10 CDJ69123.1 - 2.2 8.2 5.4 2.4 8.2 3.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF4613 PF15390.1 CDJ69123.1 - 2.2 6.3 10.1 2.5 6.1 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Gag_spuma PF03276.9 CDJ69123.1 - 2.3 6.4 17.5 2.3 6.4 12.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Serinc PF03348.10 CDJ69123.1 - 2.3 6.8 9.3 2.3 6.8 6.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CagX PF03524.10 CDJ69123.1 - 2.3 7.4 7.4 2.2 7.4 5.1 1.1 1 0 0 1 1 1 0 Conjugal transfer protein RED_N PF07808.8 CDJ69123.1 - 2.4 7.3 17.2 2.7 7.1 11.9 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2126 PF09899.4 CDJ69123.1 - 2.6 5.9 8.5 2.7 5.9 5.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Folate_carrier PF01770.13 CDJ69123.1 - 2.6 6.4 7.0 2.5 6.4 4.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF3675 PF12428.3 CDJ69123.1 - 2.7 8.2 6.2 3.2 8.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) GvpL_GvpF PF06386.6 CDJ69123.1 - 2.7 7.5 12.5 2.7 7.5 8.7 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Peptidase_S15 PF02129.13 CDJ69123.1 - 2.8 7.2 7.3 2.6 7.3 5.1 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hid1 PF12722.2 CDJ69123.1 - 2.9 5.4 8.2 2.7 5.5 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1007 PF06226.8 CDJ69123.1 - 3 7.5 10.6 3.4 7.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) DUF1943 PF09172.6 CDJ69123.1 - 3.2 6.5 7.8 3.3 6.4 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Glyco_transf_15 PF01793.11 CDJ69123.1 - 3.2 6.5 8.1 3.1 6.6 5.6 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PspB PF06667.7 CDJ69123.1 - 3.4 7.6 6.4 4.3 7.3 4.4 1.3 1 0 0 1 1 1 0 Phage shock protein B DUF1980 PF09323.5 CDJ69123.1 - 3.4 7.3 5.8 3.3 7.3 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2828 PF11443.3 CDJ69123.1 - 3.9 5.5 8.6 4.2 5.4 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) G-alpha PF00503.15 CDJ69123.1 - 4 6.0 10.4 4.9 5.7 7.2 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Pex16 PF08610.5 CDJ69123.1 - 4.3 6.2 10.7 4 6.3 7.4 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) AUX_IAA PF02309.11 CDJ69123.1 - 5 6.8 9.3 5.5 6.6 6.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Presenilin PF01080.12 CDJ69123.1 - 5.1 5.8 8.2 5.8 5.6 5.7 1.0 1 0 0 1 1 1 0 Presenilin DUF3043 PF11241.3 CDJ69123.1 - 5.1 6.6 8.0 5.4 6.5 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) LpxB PF02684.10 CDJ69123.1 - 5.8 5.4 8.3 5.9 5.4 5.7 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Ndc1_Nup PF09531.5 CDJ69123.1 - 5.9 5.1 10.5 6.4 5.0 7.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3682 PF12446.3 CDJ69123.1 - 5.9 7.1 23.3 8.9 6.6 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3276 PF11680.3 CDJ69123.1 - 6.1 6.6 8.0 9.1 6.1 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) DUF853 PF05872.7 CDJ69123.1 - 6.3 5.0 10.2 6.5 4.9 7.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3373 PF11853.3 CDJ69123.1 - 6.4 5.1 11.9 6.5 5.1 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) RbsD_FucU PF05025.8 CDJ69123.1 - 6.4 7.0 7.0 7.3 6.8 4.8 1.1 1 0 0 1 1 1 0 RbsD / FucU transport protein family GD_AH_C PF04295.8 CDJ69123.1 - 7.1 5.1 7.3 7.5 5.0 5.0 1.0 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus Baculo_PP31 PF05311.6 CDJ69123.1 - 7.3 5.7 11.3 9.2 5.4 7.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Adeno_VII PF03228.9 CDJ69123.1 - 8.1 7.0 8.1 9.2 6.8 5.6 1.1 1 0 0 1 1 1 0 Adenoviral core protein VII Neur_chan_memb PF02932.11 CDJ69123.1 - 8.3 6.2 6.7 8.7 6.1 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BaxI_1 PF12811.2 CDJ69123.1 - 9.6 5.2 6.1 12 4.8 4.2 1.3 1 0 0 1 1 1 0 Bax inhibitor 1 like AAA_22 PF13401.1 CDJ69126.1 - 1.8 8.6 6.9 7.5 6.7 0.0 4.0 3 0 0 3 3 3 0 AAA domain EMP24_GP25L PF01105.19 CDJ69127.1 - 0.0037 17.0 8.2 0.0063 16.2 4.8 2.1 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD ATS PF15445.1 CDJ69127.1 - 0.026 13.6 0.2 0.037 13.1 0.1 1.4 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 PA14_2 PF10528.4 CDJ69127.1 - 0.12 12.3 0.1 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 GLEYA domain EMP24_GP25L PF01105.19 CDJ69128.1 - 1.4e-09 37.9 0.2 1.6e-09 37.7 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MIS13 PF08202.6 CDJ69128.1 - 0.0053 15.8 0.0 0.0057 15.7 0.0 1.0 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Golgin_A5 PF09787.4 CDJ69128.1 - 0.063 11.8 0.1 0.067 11.7 0.1 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Blt1 PF12754.2 CDJ69129.1 - 1.3 8.5 7.3 1.7 8.1 5.0 1.3 1 0 0 1 1 1 0 Cell-cycle control medial ring component DUF2987 PF11205.3 CDJ69129.1 - 2.1 7.9 11.5 0.056 13.1 3.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) FimP PF09766.4 CDJ69130.1 - 0.0013 17.8 1.8 0.0013 17.8 1.2 1.7 2 0 0 2 2 2 1 Fms-interacting protein Ribosomal_60s PF00428.14 CDJ69130.1 - 0.029 14.7 11.1 0.029 14.7 7.7 7.3 5 2 0 5 5 5 0 60s Acidic ribosomal protein Spt20 PF12090.3 CDJ69130.1 - 0.18 11.1 5.3 0.031 13.6 0.7 1.9 2 0 0 2 2 2 0 Spt20 family POPLD PF08170.7 CDJ69130.1 - 9 6.2 8.7 0.28 11.0 0.4 2.4 2 0 0 2 2 2 0 POPLD (NUC188) domain Peptidase_M24 PF00557.19 CDJ69131.1 - 1.1e-19 70.8 0.1 1.1e-19 70.8 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 CRAL_TRIO PF00650.15 CDJ69133.1 - 2.2e-05 23.9 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2518 PF10726.4 CDJ69134.1 - 0.16 11.5 0.4 0.28 10.6 0.3 1.5 1 0 0 1 1 1 0 Protein of function (DUF2518) ABC2_membrane_4 PF12730.2 CDJ69134.1 - 5.4 6.0 8.5 46 3.0 5.9 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein GIDA PF01134.17 CDJ69136.1 - 5.5e-69 232.9 7.9 2.4e-61 207.7 0.0 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Acetyltransf_1 PF00583.19 CDJ69137.1 - 2.5e-07 30.6 0.2 2.5e-07 30.6 0.2 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDJ69137.1 - 5.1e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.27 CDJ69138.1 - 2.9e-09 36.4 10.9 0.0002 21.1 0.0 4.8 6 0 0 6 6 6 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 CDJ69138.1 - 2e-05 23.7 2.6 0.26 10.2 0.4 3.1 3 0 0 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4446 PF14584.1 CDJ69138.1 - 0.088 12.6 0.2 0.088 12.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF2360 PF10152.4 CDJ69138.1 - 0.11 12.7 14.7 0.029 14.6 4.2 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Spt20 PF12090.3 CDJ69138.1 - 0.26 10.6 0.1 0.26 10.6 0.0 2.6 2 1 0 2 2 2 0 Spt20 family BAF1_ABF1 PF04684.8 CDJ69138.1 - 0.42 9.4 21.9 0.0064 15.4 1.9 2.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Neur_chan_memb PF02932.11 CDJ69138.1 - 1.3 8.9 0.0 1.3 8.9 0.0 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF755 PF05501.6 CDJ69139.1 - 0.0025 17.8 28.7 0.0025 17.8 19.9 4.4 3 1 0 4 4 4 2 Domain of unknown function (DUF755) RAP1 PF07218.6 CDJ69139.1 - 0.35 8.8 5.0 0.51 8.3 3.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IMCp PF12314.3 CDJ69142.1 - 1.5e-18 66.7 51.5 1.6e-14 53.7 19.2 2.1 1 1 1 2 2 2 2 Inner membrane complex protein IMCp PF12314.3 CDJ69143.1 - 2.7e-25 88.3 50.3 2.2e-24 85.3 24.1 2.1 1 1 1 2 2 2 2 Inner membrane complex protein Macoilin PF09726.4 CDJ69145.1 - 0.0028 16.0 2.7 0.0096 14.2 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein SAGA-Tad1 PF12767.2 CDJ69145.1 - 2.5 7.6 18.2 7.3 6.1 12.6 1.7 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_M16 PF00675.15 CDJ69147.1 - 0.03 14.0 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) DUF3563 PF12086.3 CDJ69149.1 - 0.074 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) PNK3P PF08645.6 CDJ69150.1 - 2.3e-40 137.6 0.0 4.4e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CDJ69150.1 - 1.5e-13 50.8 1.8 4.7e-13 49.2 0.4 2.5 2 1 0 2 2 1 1 AAA domain tRNA_lig_kinase PF08303.6 CDJ69150.1 - 0.00018 21.4 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_28 PF13521.1 CDJ69150.1 - 0.00063 19.7 0.1 0.0032 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CDJ69150.1 - 0.0019 18.3 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain HAD_2 PF13419.1 CDJ69150.1 - 0.0022 18.2 0.2 0.43 10.7 0.0 2.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_16 PF13191.1 CDJ69150.1 - 0.0031 17.5 4.6 0.0031 17.5 0.9 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CDJ69150.1 - 0.0031 18.2 0.0 0.0089 16.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 CDJ69150.1 - 0.0054 16.2 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CDJ69150.1 - 0.0064 15.6 0.0 0.019 14.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CDJ69150.1 - 0.0098 16.1 0.1 0.02 15.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CDJ69150.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.7 2 0 0 2 2 1 0 ABC transporter 6PF2K PF01591.13 CDJ69150.1 - 0.016 14.2 0.0 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 6-phosphofructo-2-kinase cobW PF02492.14 CDJ69150.1 - 0.017 14.5 0.0 0.066 12.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CDJ69150.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CDJ69150.1 - 0.025 13.6 0.2 0.1 11.6 0.1 2.0 2 1 1 3 3 3 0 Zeta toxin Miro PF08477.8 CDJ69150.1 - 0.028 14.8 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 CDJ69150.1 - 0.033 13.8 0.6 0.085 12.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 CDJ69150.1 - 0.034 13.9 1.6 0.06 13.1 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain ArgK PF03308.11 CDJ69150.1 - 0.04 12.6 0.0 0.078 11.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 CDJ69150.1 - 0.041 13.6 0.0 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KTI12 PF08433.5 CDJ69150.1 - 0.042 13.0 0.3 0.14 11.3 0.1 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 CDJ69150.1 - 0.059 12.7 0.1 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CDJ69150.1 - 0.067 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NIF PF03031.13 CDJ69150.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase HAD PF12710.2 CDJ69150.1 - 0.08 13.1 0.7 1.1 9.3 0.4 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_14 PF13173.1 CDJ69150.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CDJ69150.1 - 0.15 11.5 0.0 0.34 10.2 0.0 1.6 2 0 0 2 2 1 0 AAA-like domain DUF815 PF05673.8 CDJ69150.1 - 0.16 10.8 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) V-ATPase_G PF03179.10 CDJ69151.1 - 8.4e-06 26.0 9.0 1.4e-05 25.3 6.2 1.4 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 CDJ69151.1 - 0.00012 21.3 9.1 0.0002 20.6 6.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 CDJ69151.1 - 0.012 15.3 11.8 0.024 14.4 8.2 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF444 PF04285.7 CDJ69151.1 - 0.045 12.3 1.4 0.072 11.7 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF444) RRM_1 PF00076.17 CDJ69152.1 - 0.00042 19.9 0.0 0.65 9.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ69152.1 - 0.00045 20.1 0.3 0.42 10.6 0.0 4.1 4 0 0 4 4 4 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ69152.1 - 0.00096 18.9 0.7 7.3 6.5 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3633 PF12315.3 CDJ69153.1 - 1.6e-07 30.8 0.1 0.00014 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3633) PAT1 PF09770.4 CDJ69153.1 - 0.76 7.9 30.4 0.041 12.1 16.9 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.4 CDJ69154.1 - 2.2 7.0 11.2 3.3 6.4 7.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_L_2 PF13656.1 CDJ69155.1 - 3.9e-15 55.0 0.0 6e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ING PF12998.2 CDJ69156.1 - 0.00025 21.2 0.1 0.00025 21.2 0.1 2.3 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding SR-25 PF10500.4 CDJ69156.1 - 0.0052 16.2 8.2 0.0052 16.2 5.7 4.7 5 0 0 5 5 5 3 Nuclear RNA-splicing-associated protein PP2C PF00481.16 CDJ69157.1 - 7.8e-30 104.1 0.0 1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C BCIP PF13862.1 CDJ69158.1 - 1.4e-32 112.8 0.1 1.4e-32 112.8 0.0 2.3 2 1 0 2 2 2 1 p21-C-terminal region-binding protein Ribosomal_L15e PF00827.12 CDJ69159.1 - 1e-87 292.6 11.7 1.2e-87 292.4 8.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF1574 PF07611.6 CDJ69160.1 - 1.8 7.3 2.1 1.7 7.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) Btz PF09405.5 CDJ69163.1 - 5.6e-10 39.3 12.5 5.6e-10 39.3 8.7 2.5 3 1 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding DUF4407 PF14362.1 CDJ69163.1 - 0.27 10.1 2.2 0.4 9.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3275 PF11679.3 CDJ69163.1 - 3.9 7.0 7.5 6.9 6.2 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF3357 PF11837.3 CDJ69164.1 - 0.086 12.6 1.2 0.26 11.1 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) GDA1_CD39 PF01150.12 CDJ69165.1 - 2.7e-09 36.0 0.8 0.00016 20.3 0.3 2.6 3 0 0 3 3 3 2 GDA1/CD39 (nucleoside phosphatase) family Abhydrolase_9 PF10081.4 CDJ69169.1 - 0.029 13.0 0.2 0.044 12.4 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family MDFI PF15316.1 CDJ69170.1 - 0.00058 19.8 0.5 0.00058 19.8 0.3 3.0 3 0 0 3 3 3 1 MyoD family inhibitor RCC1_2 PF13540.1 CDJ69170.1 - 0.00075 19.0 0.5 0.0031 17.0 0.1 2.2 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Med15 PF09606.5 CDJ69170.1 - 0.0018 16.5 15.5 0.0018 16.5 10.7 2.2 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.1 CDJ69170.1 - 0.014 14.3 7.2 0.022 13.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3025 PF11227.3 CDJ69170.1 - 0.23 10.9 2.1 0.36 10.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) AAA_23 PF13476.1 CDJ69170.1 - 0.68 10.2 4.3 0.91 9.8 3.0 1.1 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 CDJ69170.1 - 0.73 9.5 2.9 1 9.0 2.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ69170.1 - 1.3 7.1 11.6 17 3.4 9.8 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 HemX PF04375.9 CDJ69170.1 - 2.4 6.6 18.1 4.3 5.8 12.6 1.3 1 0 0 1 1 1 0 HemX Phage_portal PF04860.7 CDJ69171.1 - 0.16 10.6 2.8 0.25 9.9 1.9 1.2 1 0 0 1 1 1 0 Phage portal protein PhaP_Bmeg PF09602.5 CDJ69171.1 - 1.5 8.6 12.7 0.031 14.1 3.3 2.1 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ACDC PF14733.1 CDJ69172.1 - 2.7e-08 33.8 0.1 8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.15 CDJ69172.1 - 0.00085 19.4 2.8 0.00085 19.4 2.0 2.3 3 0 0 3 3 3 1 AP2 domain Gly_transf_sug PF04488.10 CDJ69175.1 - 6.3e-07 29.7 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CDJ69175.1 - 0.6 8.5 0.2 0.92 7.9 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Pex14_N PF04695.8 CDJ69175.1 - 6 6.9 10.1 0.49 10.4 1.6 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2423 PF10338.4 CDJ69176.1 - 5.3e-12 45.4 1.0 1.2e-11 44.4 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.4 CDJ69176.1 - 0.24 11.6 2.4 0.2 11.8 0.6 1.7 2 0 0 2 2 2 0 Learning-associated protein Ribosomal_60s PF00428.14 CDJ69176.1 - 0.41 11.0 11.9 0.68 10.3 7.3 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein PPR_3 PF13812.1 CDJ69176.1 - 1.8 9.0 5.1 36 5.0 0.1 3.3 3 1 0 3 3 3 0 Pentatricopeptide repeat domain Ribosomal_S11 PF00411.14 CDJ69177.1 - 3.3e-27 94.8 1.0 3.3e-27 94.8 0.7 2.3 2 0 0 2 2 2 1 Ribosomal protein S11 DUF814 PF05670.8 CDJ69177.1 - 0.13 12.1 0.1 0.57 10.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF814) RNA_pol_A_bac PF01000.21 CDJ69178.1 - 2e-12 47.2 0.0 3.9e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CDJ69178.1 - 3.2e-10 38.9 0.0 1.9e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.1 CDJ69178.1 - 0.023 14.9 0.7 0.047 13.9 0.5 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CDJ69178.1 - 0.04 14.3 0.6 0.089 13.1 0.4 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CDJ69178.1 - 0.1 12.4 0.5 0.22 11.3 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain SIR2 PF02146.12 CDJ69179.1 - 0.00025 20.8 0.0 0.00025 20.8 0.0 2.8 4 0 0 4 4 4 1 Sir2 family DUF2967 PF11179.3 CDJ69179.1 - 0.0056 16.2 11.0 0.0056 16.2 7.6 8.6 8 1 1 9 9 9 2 Protein of unknown function (DUF2967) Hist_deacetyl PF00850.14 CDJ69180.1 - 0.0056 16.0 0.0 0.0088 15.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF2207 PF09972.4 CDJ69180.1 - 0.58 8.6 10.7 0.79 8.2 7.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_transf_20 PF00982.16 CDJ69181.1 - 1.4e-155 518.3 1.6 1.3e-129 432.7 0.0 3.8 4 0 0 4 4 4 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CDJ69181.1 - 6.8e-16 57.8 1.3 2e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Trehalose-phosphatase Glycos_transf_1 PF00534.15 CDJ69181.1 - 0.00047 19.6 0.1 0.22 10.9 0.0 3.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 FimP PF09766.4 CDJ69181.1 - 0.014 14.5 0.6 0.014 14.5 0.4 5.5 5 1 0 5 5 5 0 Fms-interacting protein Glyco_transf_5 PF08323.6 CDJ69181.1 - 0.032 13.7 0.3 0.091 12.2 0.2 1.7 1 0 0 1 1 1 0 Starch synthase catalytic domain GRASP55_65 PF04495.9 CDJ69183.1 - 1.6e-15 57.3 0.0 2.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF2029 PF09594.5 CDJ69183.1 - 0.0064 16.0 4.5 0.0093 15.4 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) Pex14_N PF04695.8 CDJ69183.1 - 0.077 13.0 11.9 0.11 12.5 2.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4407 PF14362.1 CDJ69183.1 - 0.16 10.9 6.1 0.85 8.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Aminotran_1_2 PF00155.16 CDJ69183.1 - 0.21 10.5 1.7 1.3 7.9 0.1 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II APC_CDC26 PF10471.4 CDJ69183.1 - 0.46 11.2 14.3 4.2 8.1 1.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Activator_LAG-3 PF11498.3 CDJ69183.1 - 0.95 8.1 23.7 0.34 9.6 1.8 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PAT1 PF09770.4 CDJ69183.1 - 9.3 4.3 19.1 14 3.7 13.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PH PF00169.24 CDJ69184.1 - 0.005 17.0 0.3 0.007 16.5 0.2 1.3 1 1 0 1 1 1 1 PH domain FtsH_ext PF06480.10 CDJ69184.1 - 0.065 13.4 0.1 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsH Extracellular LRR_4 PF12799.2 CDJ69185.1 - 2.4e-05 23.8 2.1 0.011 15.3 0.0 4.2 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CDJ69185.1 - 3.7e-05 23.3 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CDJ69185.1 - 0.00035 20.2 5.3 0.025 14.3 0.4 3.5 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CDJ69185.1 - 1 9.6 4.6 1.9 8.8 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat MSP1_C PF07462.6 CDJ69185.1 - 3 6.1 8.4 4.4 5.5 5.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4613 PF15390.1 CDJ69186.1 - 0.21 9.7 1.6 0.34 9.0 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) vWA-TerF-like PF10138.4 CDJ69187.1 - 0.1 12.4 0.5 0.22 11.3 0.2 1.6 1 1 1 2 2 2 0 vWA found in TerF C terminus FlaC_arch PF05377.6 CDJ69187.1 - 0.11 12.4 0.0 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Pex14_N PF04695.8 CDJ69188.1 - 0.96 9.4 7.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAN_1 PF00024.21 CDJ69190.1 - 5e-11 42.1 0.7 1.1e-06 28.2 0.1 2.6 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 CDJ69190.1 - 1.9e-09 37.0 5.5 3.8e-06 26.5 0.3 2.5 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.6 CDJ69190.1 - 0.0072 16.1 0.1 0.0072 16.1 0.1 2.7 2 1 0 2 2 2 1 PAN-like domain BTK PF00779.14 CDJ69190.1 - 0.97 9.1 3.8 2.6 7.7 0.2 2.5 2 0 0 2 2 2 0 BTK motif DNA_ligase_A_M PF01068.16 CDJ69192.1 - 2.8e-07 30.0 0.1 2.8e-07 30.0 0.0 2.1 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_IV PF11411.3 CDJ69192.1 - 3.1e-05 23.5 1.2 6.6e-05 22.5 0.8 1.5 1 0 0 1 1 1 1 DNA ligase IV DUF1673 PF07895.6 CDJ69192.1 - 0.089 12.3 2.7 0.21 11.0 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Glyco_trans_2_3 PF13632.1 CDJ69192.1 - 2.8 7.5 7.3 9 5.9 5.1 1.9 1 0 0 1 1 1 0 Glycosyl transferase family group 2 HisKA_3 PF07730.8 CDJ69193.1 - 3.8 7.9 7.4 7.5 6.9 1.5 3.2 2 0 0 2 2 2 0 Histidine kinase LEA_4 PF02987.11 CDJ69194.1 - 0.0061 16.3 6.6 0.0061 16.3 4.6 4.2 3 1 0 3 3 3 1 Late embryogenesis abundant protein CAP160 PF07918.6 CDJ69194.1 - 0.039 13.5 8.4 0.039 13.5 5.9 4.5 5 0 0 5 5 5 0 CAP160 repeat YtxH PF12732.2 CDJ69194.1 - 0.46 10.8 14.6 7.9e+02 0.5 10.1 2.7 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.8 CDJ69194.1 - 4 7.8 24.0 4.6 7.6 4.0 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF3292 PF11696.3 CDJ69194.1 - 5.8 4.6 15.5 6.7 4.4 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2868 PF11067.3 CDJ69195.1 - 0.00049 19.3 1.5 0.00089 18.4 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) BolA PF01722.13 CDJ69196.1 - 3.9e-24 84.4 0.4 3.9e-24 84.4 0.2 1.5 2 0 0 2 2 2 1 BolA-like protein Spt20 PF12090.3 CDJ69196.1 - 0.066 12.5 0.5 0.084 12.2 0.3 1.1 1 0 0 1 1 1 0 Spt20 family RsbRD_N PF14361.1 CDJ69196.1 - 0.16 12.4 3.0 0.25 11.8 0.0 2.2 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain CPSF_A PF03178.10 CDJ69197.1 - 9.1e-14 51.2 0.0 1.5e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region Hid1 PF12722.2 CDJ69197.1 - 0.56 7.8 4.5 0.84 7.2 3.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 CDJ69197.1 - 1.4 8.5 6.0 6 6.5 4.2 2.0 1 0 0 1 1 1 0 AUX/IAA family Asp-B-Hydro_N PF05279.6 CDJ69197.1 - 1.9 8.3 8.5 5.4 6.7 5.9 1.7 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Med5 PF08689.5 CDJ69197.1 - 9 3.8 5.7 15 3.1 4.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 Paramyxo_ncap PF00973.14 CDJ69197.1 - 9.8 4.7 5.2 16 4.0 3.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein zf-CCHC PF00098.18 CDJ69198.1 - 5.9e-08 32.2 11.8 4.8e-06 26.2 1.5 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ69198.1 - 0.0046 16.6 0.6 0.0046 16.6 0.4 2.5 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ69198.1 - 0.011 15.4 1.0 0.011 15.4 0.7 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ69198.1 - 0.015 14.9 7.5 0.053 13.2 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ69198.1 - 0.099 12.7 8.4 0.23 11.5 5.8 1.5 1 1 0 1 1 1 0 DnaJ central domain zf-C4pol PF14260.1 CDJ69198.1 - 0.11 12.4 1.8 2 8.4 0.1 2.5 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Retrotrans_gag PF03732.12 CDJ69198.1 - 0.12 12.4 0.0 0.54 10.3 0.0 2.1 3 0 0 3 3 3 0 Retrotransposon gag protein zf-CCHC_2 PF13696.1 CDJ69198.1 - 0.21 11.1 5.6 0.1 12.0 0.5 2.4 1 1 1 2 2 2 0 Zinc knuckle Asp_protease_2 PF13650.1 CDJ69199.1 - 4.7e-09 36.6 0.0 9.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CDJ69199.1 - 8.2e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CDJ69199.1 - 3e-06 26.9 0.0 6.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CDJ69199.1 - 3.5e-05 23.7 0.0 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CDJ69199.1 - 9.4e-05 22.2 0.0 0.0004 20.2 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease rve PF00665.21 CDJ69200.1 - 8.5e-18 64.5 0.0 3.7e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain GLTSCR1 PF15249.1 CDJ69200.1 - 0.009 16.0 0.4 0.1 12.7 0.1 2.3 2 0 0 2 2 2 1 Glioma tumor suppressor candidate region zf-H2C2 PF09337.5 CDJ69200.1 - 0.011 15.1 0.3 0.021 14.2 0.2 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger PPR_2 PF13041.1 CDJ69201.1 - 1.3e-12 47.4 0.0 1.7e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 CDJ69201.1 - 1.9e-08 33.8 0.0 0.0032 17.6 0.0 3.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.15 CDJ69201.1 - 4.2e-08 32.6 2.7 0.09 12.7 0.0 4.1 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.2 CDJ69201.1 - 7.5e-07 28.5 0.1 0.032 13.7 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.1 CDJ69202.1 - 5.7e-31 106.2 0.3 2.3e-15 56.2 0.0 3.3 1 1 2 3 3 3 3 PPR repeat family PPR_1 PF12854.2 CDJ69202.1 - 1e-20 72.8 1.7 9.9e-09 34.5 0.0 3.8 4 0 0 4 4 4 3 PPR repeat PPR PF01535.15 CDJ69202.1 - 3.1e-20 70.6 1.1 1.4e-06 27.8 0.0 4.4 4 1 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 CDJ69202.1 - 1.3e-17 62.4 0.1 2e-06 27.6 0.0 4.1 4 0 0 4 4 4 3 Pentatricopeptide repeat domain IFP_35_N PF07334.8 CDJ69203.1 - 0.35 10.8 0.1 0.23 11.4 0.5 5.7 5 1 0 6 6 6 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SR-25 PF10500.4 CDJ69204.1 - 2.7 7.4 9.9 4.4 6.6 6.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4094 PF13334.1 CDJ69205.1 - 0.011 16.1 0.3 0.011 16.1 0.2 5.6 5 2 1 6 6 6 0 Domain of unknown function (DUF4094) SRP-alpha_N PF04086.8 CDJ69206.1 - 4.7 6.5 29.3 5.9 6.1 20.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal IncA PF04156.9 CDJ69207.1 - 5.6e-05 22.8 11.7 5.6e-05 22.8 8.1 3.7 4 0 0 4 4 3 2 IncA protein YjgP_YjgQ PF03739.9 CDJ69207.1 - 0.00042 19.1 6.2 0.0063 15.3 0.0 2.6 3 0 0 3 3 3 2 Predicted permease YjgP/YjgQ family Spt20 PF12090.3 CDJ69207.1 - 0.0038 16.5 13.1 0.2 10.9 0.0 3.0 3 0 0 3 3 3 2 Spt20 family FA_desaturase PF00487.19 CDJ69207.1 - 0.0077 15.7 0.1 0.034 13.5 0.3 1.8 2 0 0 2 2 2 1 Fatty acid desaturase CD20 PF04103.10 CDJ69207.1 - 0.019 14.9 1.9 0.019 14.9 1.3 3.4 3 0 0 3 3 3 0 CD20-like family DUF3040 PF11239.3 CDJ69207.1 - 1.6 8.8 11.6 5.1 7.2 6.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) CDC45 PF02724.9 CDJ69207.1 - 2.1 6.2 15.0 0.81 7.6 4.6 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF2215 PF10225.4 CDJ69207.1 - 2.9 7.2 8.1 7.2 5.9 2.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) DUF1510 PF07423.6 CDJ69207.1 - 3.9 6.7 22.4 2.1 7.6 7.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Serinc PF03348.10 CDJ69207.1 - 5.5 5.5 14.8 7.7 5.0 4.7 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) Plasmodium_Vir PF05795.6 CDJ69207.1 - 6.5 5.8 6.2 0.25 10.5 0.3 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.5 CDJ69207.1 - 6.8 4.9 9.2 0.32 9.3 1.8 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.8 CDJ69207.1 - 7.4 6.0 13.1 4.9 6.5 4.2 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain GOLD_2 PF13897.1 CDJ69207.1 - 8.3 6.6 7.0 1.3 9.2 1.1 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking AAA_25 PF13481.1 CDJ69208.1 - 5.7e-20 71.5 0.0 1.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol_A_exo1 PF01612.15 CDJ69208.1 - 8.9e-13 48.0 0.0 1.8e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 3'-5' exonuclease Toprim_4 PF13662.1 CDJ69208.1 - 1.5e-09 37.7 0.0 1.6e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.1 CDJ69208.1 - 8.1e-08 32.4 0.0 8.1e-08 32.4 0.0 2.9 3 1 0 3 3 3 1 Toprim-like KaiC PF06745.8 CDJ69208.1 - 2.6e-05 23.4 0.0 6.4e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 CDJ69208.1 - 0.00028 21.0 1.2 0.0015 18.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF4574 PF15141.1 CDJ69208.1 - 0.00059 19.5 0.2 0.0029 17.2 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4574) zf-CHC2 PF01807.15 CDJ69208.1 - 0.5 9.9 4.0 1.1 8.8 2.7 1.5 1 0 0 1 1 1 0 CHC2 zinc finger S1 PF00575.18 CDJ69209.1 - 2.8e-27 94.6 0.6 8.1e-15 54.6 0.1 2.1 2 0 0 2 2 2 2 S1 RNA binding domain CSD PF00313.17 CDJ69209.1 - 0.0014 18.3 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain S1_2 PF13509.1 CDJ69209.1 - 0.0034 17.2 0.0 2.7 7.9 0.0 2.7 2 1 0 2 2 2 2 S1 domain Peptidase_C39_2 PF13529.1 CDJ69209.1 - 0.091 13.1 0.0 0.47 10.8 0.0 2.0 2 1 0 2 2 2 0 Peptidase_C39 like family DUF501 PF04417.7 CDJ69210.1 - 3.6e-18 65.7 0.7 2.6e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF501) Ribosomal_60s PF00428.14 CDJ69210.1 - 0.00027 21.2 6.4 0.00027 21.2 4.4 4.6 4 0 0 4 4 4 2 60s Acidic ribosomal protein ADP_PFK_GK PF04587.10 CDJ69210.1 - 3.3 5.8 5.7 35 2.4 0.5 3.6 4 0 0 4 4 4 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Sec3_C PF09763.4 CDJ69211.1 - 0.71 7.9 5.9 0.89 7.6 4.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Apt1 PF10351.4 CDJ69211.1 - 2.1 7.1 9.5 2.8 6.7 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.2 CDJ69211.1 - 9.4 3.7 11.6 10 3.6 8.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Secretin_N_2 PF07655.8 CDJ69211.1 - 10 6.6 19.6 34 4.8 13.6 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain PEARLI-4 PF05278.7 CDJ69212.1 - 7.3 5.8 23.0 0.034 13.5 7.5 2.9 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) AF-4 PF05110.8 CDJ69213.1 - 0.26 9.1 24.7 0.29 8.9 17.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF445 PF04286.7 CDJ69214.1 - 0.0024 17.4 9.1 0.0026 17.3 6.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF572 PF04502.8 CDJ69214.1 - 0.19 10.9 17.8 0.2 10.8 12.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF668 PF05003.7 CDJ69214.1 - 0.33 11.1 12.0 4 7.7 5.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF668) WASH-7_mid PF14744.1 CDJ69214.1 - 0.86 8.3 11.6 1.1 7.9 8.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 DUF2356 PF10189.4 CDJ69214.1 - 1.3 8.0 6.5 2.6 7.0 4.5 1.5 1 1 0 1 1 1 0 Conserved protein (DUF2356) HlyD_2 PF12700.2 CDJ69214.1 - 1.7 7.6 13.0 1.9 7.5 9.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein YpjP PF14005.1 CDJ69214.1 - 2.5 7.8 6.6 5.6 6.7 4.6 1.7 1 1 0 1 1 1 0 YpjP-like protein LMBR1 PF04791.11 CDJ69214.1 - 4.4 5.7 5.0 4.1 5.8 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SRP72 PF08492.7 CDJ69214.1 - 8.3 6.8 9.7 50 4.3 6.7 2.3 1 1 0 1 1 1 0 SRP72 RNA-binding domain SR-25 PF10500.4 CDJ69215.1 - 0.00049 19.6 2.7 0.00049 19.6 1.8 4.7 3 2 1 4 4 4 1 Nuclear RNA-splicing-associated protein Trp_oprn_chp PF09534.5 CDJ69216.1 - 0.012 15.1 3.6 0.013 15.0 2.5 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RskA PF10099.4 CDJ69216.1 - 0.018 14.7 12.2 0.02 14.6 8.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3995 PF13160.1 CDJ69216.1 - 0.021 14.8 1.1 0.021 14.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Gly-zipper_OmpA PF13436.1 CDJ69216.1 - 0.036 13.7 13.8 0.04 13.5 9.6 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_9 PF00759.14 CDJ69216.1 - 0.072 11.9 6.0 0.083 11.7 4.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF3123 PF11321.3 CDJ69216.1 - 0.074 13.3 6.6 0.083 13.1 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Ribosomal_60s PF00428.14 CDJ69216.1 - 0.096 13.0 14.9 0.12 12.7 10.3 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein ETRAMP PF09716.5 CDJ69216.1 - 0.15 12.0 1.7 0.19 11.7 1.2 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pex14_N PF04695.8 CDJ69216.1 - 0.37 10.8 12.8 0.47 10.4 8.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TAF4 PF05236.9 CDJ69216.1 - 0.42 9.8 10.1 0.43 9.8 7.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Apc15p PF05841.6 CDJ69216.1 - 0.79 10.4 9.4 0.83 10.3 6.5 1.2 1 0 0 1 1 1 0 Apc15p protein DUF3306 PF11748.3 CDJ69216.1 - 0.99 10.0 13.4 1.1 9.8 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) EPL1 PF10513.4 CDJ69216.1 - 1.2 9.3 8.9 1.3 9.2 6.2 1.0 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2232 PF09991.4 CDJ69216.1 - 1.6 7.6 3.4 1.7 7.5 2.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SR-25 PF10500.4 CDJ69216.1 - 1.6 8.1 8.0 1.7 8.1 5.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDJ69216.1 - 1.8 7.5 15.1 1.8 7.5 10.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4045 PF13254.1 CDJ69216.1 - 2.1 7.5 8.4 2.2 7.4 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hist_deacetyl PF00850.14 CDJ69216.1 - 2.2 7.5 4.9 2.4 7.3 3.4 1.0 1 0 0 1 1 1 0 Histone deacetylase domain DUF4139 PF13598.1 CDJ69216.1 - 2.5 7.3 11.3 2.2 7.4 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) WSC PF01822.14 CDJ69216.1 - 2.5 8.0 6.9 3.3 7.7 4.8 1.2 1 0 0 1 1 1 0 WSC domain TraV PF09676.5 CDJ69216.1 - 3 8.5 12.3 3.3 8.4 8.5 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Agouti PF05039.7 CDJ69216.1 - 3.6 8.0 7.3 4.6 7.6 5.0 1.2 1 0 0 1 1 1 0 Agouti protein DUF4407 PF14362.1 CDJ69216.1 - 3.7 6.4 19.1 3.8 6.3 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4557 PF15101.1 CDJ69216.1 - 5.6 6.7 20.1 6.3 6.5 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) P_C PF06640.6 CDJ69216.1 - 5.6 6.8 11.9 6.4 6.7 8.2 1.2 1 0 0 1 1 1 0 P protein C-terminus Spt20 PF12090.3 CDJ69216.1 - 6 6.1 12.7 6 6.1 8.8 1.1 1 0 0 1 1 1 0 Spt20 family Calici_coat PF00915.15 CDJ69216.1 - 6.8 5.4 6.6 6.6 5.5 4.5 1.0 1 0 0 1 1 1 0 Calicivirus coat protein DUF4175 PF13779.1 CDJ69216.1 - 7 4.2 27.3 6.8 4.2 18.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3464 PF11947.3 CDJ69216.1 - 7.4 6.0 6.1 7.3 6.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Pex16 PF08610.5 CDJ69216.1 - 7.4 5.4 6.5 6.9 5.5 4.5 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF2201_N PF13203.1 CDJ69216.1 - 7.7 5.5 13.2 7.7 5.5 9.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Draxin PF15550.1 CDJ69216.1 - 8.9 5.8 10.1 8.8 5.8 7.0 1.1 1 0 0 1 1 1 0 Draxin Suf PF05843.9 CDJ69216.1 - 9.2 5.8 14.8 9 5.9 10.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 CDJ69216.1 - 9.6 3.7 7.2 8.7 3.8 5.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ctr PF04145.10 CDJ69216.1 - 9.7 6.2 5.9 10 6.1 4.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Band_3_cyto PF07565.8 CDJ69216.1 - 9.8 5.5 7.1 9.4 5.6 4.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3498 PF12004.3 CDJ69217.1 - 0.03 13.4 2.4 0.038 13.1 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DUF2217 PF10265.4 CDJ69217.1 - 0.036 12.8 1.2 0.046 12.4 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Mucin PF01456.12 CDJ69218.1 - 0.0021 17.8 17.1 0.0021 17.8 11.8 5.6 1 1 3 4 4 4 1 Mucin-like glycoprotein AIP3 PF03915.8 CDJ69219.1 - 4.1 6.1 6.7 6.4 5.5 4.7 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 E1-E2_ATPase PF00122.15 CDJ69220.1 - 5.9e-12 45.1 0.0 5.9e-12 45.1 0.0 3.3 3 1 1 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.21 CDJ69220.1 - 4.9e-11 43.4 1.9 4.6e-09 37.0 0.0 4.5 3 2 0 4 4 4 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ69220.1 - 3e-07 30.8 1.8 1.4e-06 28.6 1.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDJ69220.1 - 0.0015 18.4 0.7 0.086 12.8 0.0 3.5 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit CAF-1_p150 PF11600.3 CDJ69221.1 - 0.0036 16.7 9.4 0.0036 16.7 6.5 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal YjgP_YjgQ PF03739.9 CDJ69221.1 - 1.7 7.2 7.0 5.4 5.6 4.8 1.7 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family rve PF00665.21 CDJ69223.1 - 9.3e-10 38.6 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain GLTSCR1 PF15249.1 CDJ69223.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 1 0 1 1 1 0 Glioma tumor suppressor candidate region RRM_1 PF00076.17 CDJ69224.1 - 1.6e-16 59.6 0.0 2.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ69224.1 - 4.2e-13 49.0 0.0 5.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ69224.1 - 4e-11 42.5 0.0 5.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIase PF02426.11 CDJ69224.1 - 0.053 13.3 0.1 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Muconolactone delta-isomerase COPI_assoc PF08507.5 CDJ69229.1 - 2.3e-11 43.5 1.1 2.7e-11 43.3 0.8 1.1 1 0 0 1 1 1 1 COPI associated protein G-patch PF01585.18 CDJ69230.1 - 7.9e-14 51.1 1.0 1.3e-13 50.4 0.7 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CDJ69230.1 - 0.00043 20.0 0.3 0.0014 18.3 0.2 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_1 PF00076.17 CDJ69230.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ69230.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4574 PF15141.1 CDJ69230.1 - 0.022 14.4 0.1 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) AAA_12 PF13087.1 CDJ69231.1 - 3.9e-52 176.5 0.0 7.5e-52 175.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDJ69231.1 - 2.7e-46 158.0 1.6 3.3e-46 157.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDJ69231.1 - 1.7e-13 50.1 0.5 5.8e-13 48.4 0.0 2.1 3 0 0 3 3 1 1 Part of AAA domain AAA_30 PF13604.1 CDJ69231.1 - 1.3e-10 41.1 0.0 2.7e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.9 CDJ69231.1 - 5.3e-05 22.3 0.0 0.0051 15.8 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.4 CDJ69231.1 - 0.0004 19.4 0.2 0.026 13.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) dsrm PF00035.20 CDJ69231.1 - 0.00083 19.8 0.5 0.25 11.9 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif PhoH PF02562.11 CDJ69231.1 - 0.001 18.3 0.0 0.0039 16.4 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.7 CDJ69231.1 - 0.0011 18.6 0.0 0.0028 17.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.12 CDJ69231.1 - 0.0021 17.5 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CDJ69231.1 - 0.011 15.2 0.0 1.3 8.4 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 CDJ69231.1 - 0.011 15.5 0.0 0.051 13.3 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.24 CDJ69231.1 - 0.013 15.7 0.0 0.064 13.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CDJ69231.1 - 0.021 14.3 0.1 0.21 11.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 CDJ69231.1 - 0.023 14.1 0.3 0.094 12.1 0.0 2.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase UvrD-helicase PF00580.16 CDJ69231.1 - 0.026 13.8 0.3 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 CDJ69231.1 - 0.062 13.2 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain Mg_chelatase PF01078.16 CDJ69231.1 - 0.078 12.1 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CDJ69231.1 - 0.092 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDJ69231.1 - 0.14 12.3 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DSPc PF00782.15 CDJ69232.1 - 1.1e-21 76.8 0.0 1.2e-18 66.9 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.17 CDJ69232.1 - 0.0034 17.0 0.0 0.042 13.5 0.0 2.4 2 0 0 2 2 2 1 Gelsolin repeat Y_phosphatase PF00102.22 CDJ69232.1 - 0.0064 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CLU PF13236.1 CDJ69233.1 - 0.15 11.4 0.0 0.38 10.1 0.0 1.6 2 0 0 2 2 2 0 Clustered mitochondria TPR_12 PF13424.1 CDJ69234.1 - 0.049 13.5 0.1 0.17 11.8 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat MORN PF02493.15 CDJ69235.1 - 9.2e-23 78.5 36.2 0.0012 18.4 0.0 9.4 10 0 0 10 10 10 7 MORN repeat Avl9 PF09794.4 CDJ69235.1 - 2.2e-11 42.9 0.1 7.5e-11 41.1 0.0 1.6 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.16 CDJ69235.1 - 0.003 17.3 1.4 0.0041 16.8 0.3 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain PDZ PF00595.19 CDJ69236.1 - 0.00052 20.1 0.0 0.00099 19.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CDJ69236.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PAP2 PF01569.16 CDJ69238.1 - 2.2e-18 66.1 0.8 2.2e-18 66.1 0.6 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 CDJ69238.1 - 0.015 15.5 4.9 0.38 11.0 0.2 3.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal PAP2 PF01569.16 CDJ69239.1 - 3.5e-18 65.5 0.3 3.5e-18 65.5 0.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF805 PF05656.9 CDJ69239.1 - 0.041 13.6 0.5 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF805) ADK PF00406.17 CDJ69240.1 - 2.2e-56 189.9 0.0 3.3e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CDJ69240.1 - 1.9e-16 59.4 1.1 3.1e-16 58.7 0.1 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CDJ69240.1 - 2e-10 40.6 0.0 1.2e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDJ69240.1 - 8.5e-06 26.5 0.0 1.5e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDJ69240.1 - 0.00044 20.5 1.3 0.00093 19.4 0.0 2.2 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.1 CDJ69240.1 - 0.004 17.1 0.1 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain DAP3 PF10236.4 CDJ69240.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 dNK PF01712.14 CDJ69240.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase Abhydrolase_5 PF12695.2 CDJ69242.1 - 4.3e-19 68.7 0.0 4.3e-19 68.7 0.0 3.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CDJ69242.1 - 0.0013 18.1 0.3 0.0095 15.3 0.2 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CDJ69242.1 - 0.045 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family PEMT PF04191.8 CDJ69243.1 - 0.016 15.2 0.3 0.49 10.5 0.1 2.2 2 0 0 2 2 2 0 Phospholipid methyltransferase Na_Ca_ex PF01699.19 CDJ69244.1 - 5.6e-40 136.1 31.8 5.3e-22 77.9 9.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ribosomal_L37ae PF01780.14 CDJ69245.1 - 2.8e-39 132.8 8.5 3.3e-39 132.6 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 CDJ69245.1 - 0.0024 17.2 2.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CDJ69245.1 - 0.0048 16.6 2.2 0.0068 16.1 1.6 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Elf1 PF05129.8 CDJ69245.1 - 0.0055 16.3 0.1 0.0086 15.7 0.1 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 CDJ69245.1 - 0.033 13.8 0.7 0.048 13.3 0.5 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 CDJ69245.1 - 0.036 14.0 1.3 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain GFA PF04828.9 CDJ69245.1 - 0.098 12.6 0.7 5.7 6.9 0.1 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 CDJ69245.1 - 0.11 11.7 1.2 0.27 10.5 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_4 PF13894.1 CDJ69245.1 - 0.12 12.7 1.8 7.2 7.1 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Rep_fac-A_C PF08646.5 CDJ69245.1 - 0.13 11.9 1.8 0.61 9.7 1.2 2.0 1 1 0 1 1 1 0 Replication factor-A C terminal domain zf-Di19 PF05605.7 CDJ69245.1 - 0.14 12.2 0.8 0.14 12.2 0.6 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Lar_restr_allev PF14354.1 CDJ69245.1 - 0.38 11.0 4.4 2.6 8.4 3.1 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-H2C2_2 PF13465.1 CDJ69245.1 - 1.4 9.3 6.8 0.63 10.4 1.3 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 CDJ69245.1 - 6.1 7.3 6.9 6.3 7.3 0.2 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type HSP70 PF00012.15 CDJ69246.1 - 4.6e-11 41.3 0.0 6e-11 40.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Cuticle_3 PF11018.3 CDJ69246.1 - 0.46 10.6 30.7 0.56 10.3 21.3 1.2 1 0 0 1 1 1 0 Pupal cuticle protein C1 DcuC PF03606.10 CDJ69247.1 - 3.3 5.8 5.3 7.1 4.7 3.7 1.5 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier SCO1-SenC PF02630.9 CDJ69248.1 - 4.3e-26 91.5 0.0 4.3e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 SCO1/SenC TFIIA PF03153.8 CDJ69248.1 - 0.0029 17.5 18.1 0.0049 16.8 12.6 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 CDJ69248.1 - 0.025 12.2 4.4 0.03 12.0 3.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.6 CDJ69248.1 - 0.1 11.7 3.6 0.036 13.2 0.3 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Med15 PF09606.5 CDJ69248.1 - 0.19 9.8 33.3 0.0046 15.2 18.5 1.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDJ69248.1 - 0.41 9.6 16.0 0.9 8.5 11.1 1.5 1 0 0 1 1 1 0 Fms-interacting protein DUF4407 PF14362.1 CDJ69248.1 - 5.4 5.8 22.6 0.028 13.3 9.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MAR_sialic_bdg PF10564.4 CDJ69251.1 - 9.9e-07 28.4 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat PAT1 PF09770.4 CDJ69252.1 - 6.8 4.7 51.8 7.9 4.5 35.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAR_sialic_bdg PF10564.4 CDJ69253.1 - 6e-37 125.3 19.3 4e-14 52.1 0.2 3.6 4 0 0 4 4 4 3 Sialic-acid binding micronemal adhesive repeat Rieske PF00355.21 CDJ69254.1 - 1.9e-18 65.7 0.2 3.8e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 CDJ69254.1 - 1.8e-09 37.2 0.0 3.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_2 PF07992.9 CDJ69254.1 - 7.6e-06 25.9 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase E_Pc_C PF06752.7 CDJ69254.1 - 0.007 15.8 0.9 0.007 15.8 0.6 3.1 3 0 0 3 3 2 2 Enhancer of Polycomb C-terminus Pyr_redox_3 PF13738.1 CDJ69254.1 - 0.026 14.5 0.0 0.21 11.6 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CDJ69254.1 - 0.035 14.2 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CDJ69254.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Peptidase_S49_N PF08496.5 CDJ69254.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.0 3 0 0 3 3 3 0 Peptidase family S49 N-terminal FAM163 PF15069.1 CDJ69254.1 - 1.4 9.4 5.8 3.7 8.0 0.2 2.3 2 0 0 2 2 2 0 FAM163 family Med15 PF09606.5 CDJ69254.1 - 7.1 4.6 37.1 0.049 11.8 2.4 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.9 CDJ69254.1 - 8.9 6.2 21.0 2.8 7.8 1.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Myb_DNA-binding PF00249.26 CDJ69255.1 - 0.0061 16.5 0.1 0.019 15.0 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain MENTAL PF10457.4 CDJ69255.1 - 0.39 10.3 0.6 1.4 8.5 0.4 2.0 1 0 0 1 1 1 0 Cholesterol-capturing domain DUF4092 PF13322.1 CDJ69256.1 - 0.23 11.1 1.4 0.5 10.0 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) DUF4231 PF14015.1 CDJ69257.1 - 0.017 15.1 0.1 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PNRC PF15365.1 CDJ69257.1 - 0.22 11.5 2.5 0.29 11.1 0.2 1.9 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator SR-25 PF10500.4 CDJ69257.1 - 4 6.8 11.2 5.3 6.4 7.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4228 PF14009.1 CDJ69258.1 - 1.2 9.2 19.3 0.77 9.8 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF572 PF04502.8 CDJ69258.1 - 3.6 6.7 17.1 0.48 9.5 2.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF2413 PF10310.4 CDJ69258.1 - 3.8 6.2 16.7 1.8 7.3 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Phage_GPD PF05954.6 CDJ69258.1 - 5.7 6.0 8.7 0.3 10.2 0.6 2.0 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) SpoIIIAH PF12685.2 CDJ69258.1 - 6.7 6.1 16.3 0.62 9.5 3.4 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Pkinase PF00069.20 CDJ69260.1 - 8e-37 126.7 0.0 7e-36 123.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69260.1 - 8.8e-10 38.0 0.0 0.00019 20.6 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase UPF0164 PF03687.8 CDJ69260.1 - 0.05 12.1 2.4 0.1 11.1 1.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) Rotamase_2 PF13145.1 CDJ69261.1 - 0.03 14.9 5.9 0.24 12.0 0.0 2.7 3 0 0 3 3 3 0 PPIC-type PPIASE domain Acetyltransf_1 PF00583.19 CDJ69262.1 - 2.1e-13 50.1 0.0 3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDJ69262.1 - 3.5e-09 36.6 0.0 6.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDJ69262.1 - 1.3e-07 31.7 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CDJ69262.1 - 7.9e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CDJ69262.1 - 2.4e-05 24.5 0.0 3.4e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CDJ69262.1 - 0.00041 20.2 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDJ69262.1 - 0.0007 19.4 0.1 0.0024 17.7 0.0 1.9 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 CDJ69262.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 GNAT acetyltransferase 2 Zip PF02535.17 CDJ69264.1 - 4.9e-15 55.3 1.1 4.9e-15 55.3 0.8 4.2 2 2 0 4 4 4 1 ZIP Zinc transporter SR-25 PF10500.4 CDJ69264.1 - 0.0002 20.8 17.3 0.0002 20.8 12.0 5.4 5 0 0 5 5 5 3 Nuclear RNA-splicing-associated protein OmpH PF03938.9 CDJ69264.1 - 0.0012 18.7 22.3 0.0012 18.7 15.5 4.8 3 2 0 3 3 3 2 Outer membrane protein (OmpH-like) DUF2232 PF09991.4 CDJ69264.1 - 1.5 7.7 7.8 0.62 9.0 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2232) Peptidase_M16_C PF05193.16 CDJ69266.1 - 6.6e-05 22.6 0.8 0.01 15.5 0.1 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Helicase_C PF00271.26 CDJ69268.1 - 0.0069 16.2 0.1 0.049 13.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 CDJ69268.1 - 0.019 15.0 0.1 0.019 15.0 0.0 3.3 3 0 0 3 3 3 0 Helicase associated domain (HA2) Crust_neuro_H PF03858.8 CDJ69269.1 - 0.0094 16.5 14.6 9.9 6.8 0.1 6.0 5 0 0 5 5 5 4 Crustacean neurohormone H DDHD PF02862.12 CDJ69272.1 - 2.2 8.0 15.1 2.9 7.6 10.5 1.2 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.1 CDJ69272.1 - 2.7 6.4 9.1 3.1 6.1 6.3 1.2 1 0 0 1 1 1 0 Raftlin DUF2076 PF09849.4 CDJ69272.1 - 4.2 7.3 12.0 5.6 6.9 8.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF605 PF04652.11 CDJ69272.1 - 7 5.9 25.4 8.3 5.6 17.6 1.0 1 0 0 1 1 1 0 Vta1 like UQ_con PF00179.21 CDJ69273.1 - 1.3e-46 157.4 0.0 1.4e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDJ69273.1 - 1.5e-05 24.7 0.0 1.8e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CDJ69273.1 - 0.00094 19.0 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CDJ69273.1 - 0.032 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain RRM_6 PF14259.1 CDJ69274.1 - 6.2e-30 102.9 0.3 2.6e-14 52.9 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ69274.1 - 1.4e-27 95.1 0.1 2.9e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ69274.1 - 2.6e-10 39.9 0.1 5.4e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15 PF09606.5 CDJ69274.1 - 0.012 13.8 68.0 0.012 13.8 12.6 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ69274.1 - 1.4 8.5 29.5 3.1 7.4 8.3 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Zip PF02535.17 CDJ69274.1 - 4.5 6.1 8.2 11 4.9 2.4 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Cohesin_load PF10345.4 CDJ69275.1 - 0.071 11.3 0.0 0.093 10.9 0.0 1.1 1 0 0 1 1 1 0 Cohesin loading factor Oxysterol_BP PF01237.13 CDJ69276.1 - 4.1e-60 203.1 2.3 5.4e-43 146.8 0.0 2.9 2 1 1 3 3 3 2 Oxysterol-binding protein PH PF00169.24 CDJ69276.1 - 1.2e-10 41.5 0.3 2.5e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 PH domain Abhydrolase_6 PF12697.2 CDJ69277.1 - 6.4e-17 62.2 1.7 5.2e-16 59.2 1.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ69277.1 - 5.4e-09 35.9 0.0 0.0096 15.4 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CDJ69277.1 - 8.2e-06 25.6 0.0 5.5e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CDJ69277.1 - 0.048 13.2 0.2 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 PGAP1-like protein DUF3148 PF11347.3 CDJ69279.1 - 0.16 11.5 0.0 0.44 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) DUF1625 PF07787.7 CDJ69280.1 - 1.1e-15 57.6 0.0 1.8e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) Mid2 PF04478.7 CDJ69281.1 - 0.00097 18.5 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4381 PF14316.1 CDJ69281.1 - 0.017 15.2 0.2 0.36 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) FAM176 PF14851.1 CDJ69281.1 - 0.025 14.2 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 FAM176 family cEGF PF12662.2 CDJ69281.1 - 0.05 13.2 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like TrbC PF04956.8 CDJ69281.1 - 0.55 10.2 5.6 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 TrbC/VIRB2 family MARCKS PF02063.12 CDJ69282.1 - 0.016 15.0 7.6 0.021 14.6 5.2 1.1 1 0 0 1 1 1 0 MARCKS family Clp_N PF02861.15 CDJ69282.1 - 0.025 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Clp amino terminal domain Shadoo PF14999.1 CDJ69282.1 - 1 9.2 7.1 1.6 8.5 4.9 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Patched PF02460.13 CDJ69283.1 - 8.9e-106 354.6 0.0 4.9e-66 223.2 0.0 3.3 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 CDJ69283.1 - 1.2e-29 102.7 4.8 1.2e-29 102.7 3.3 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 CDJ69283.1 - 3.9e-05 21.3 11.8 7.6e-05 20.3 8.2 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family DUF4525 PF15027.1 CDJ69283.1 - 0.091 12.2 0.6 0.29 10.6 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Bromodomain PF00439.20 CDJ69285.1 - 3.4e-15 55.7 0.0 6.4e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3591 PF12157.3 CDJ69285.1 - 1.3e-14 53.5 0.0 2.8e-07 29.3 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CDJ69285.1 - 0.0012 18.4 1.1 0.0032 17.0 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle HlyIII PF03006.15 CDJ69286.1 - 3.8e-14 52.6 20.5 7e-14 51.7 14.2 1.4 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.20 CDJ69287.1 - 5e-12 45.5 0.0 7.3e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 CDJ69287.1 - 1e-07 31.1 0.0 1.3e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDJ69287.1 - 1.7e-06 27.3 0.0 3.4e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Flavi_propep PF01570.12 CDJ69287.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide Pkinase PF00069.20 CDJ69288.1 - 4.2e-12 45.7 0.0 7.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDJ69288.1 - 2.4e-09 36.5 0.0 4.1e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDJ69288.1 - 1.5e-05 24.2 0.0 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDJ69289.1 - 1.7e-11 43.8 0.0 4.6e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDJ69289.1 - 6e-07 28.7 0.0 1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDJ69289.1 - 1.6e-06 27.4 0.0 2.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ69290.1 - 5.7e-08 32.0 0.0 2.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 CDJ69290.1 - 3.4e-06 26.4 0.0 5.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69290.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PPI_Ypi1 PF07491.6 CDJ69291.1 - 3.4e-21 74.6 0.1 3.4e-21 74.6 0.1 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor SR-25 PF10500.4 CDJ69291.1 - 0.00034 20.1 10.9 0.00039 19.9 7.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MTBP_C PF14920.1 CDJ69291.1 - 0.022 14.2 8.2 0.024 14.1 5.7 1.0 1 0 0 1 1 1 0 MDM2-binding Metallophos PF00149.23 CDJ69293.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Pkinase PF00069.20 CDJ69294.1 - 1.3e-53 181.7 0.1 2.9e-53 180.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69294.1 - 3.6e-28 98.3 0.4 1.4e-27 96.4 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase SPX PF03105.14 CDJ69294.1 - 0.0066 16.2 1.7 0.0093 15.7 1.2 1.1 1 0 0 1 1 1 1 SPX domain PAT1 PF09770.4 CDJ69294.1 - 4.7 5.3 39.6 5.8 5.0 27.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DnaJ PF00226.26 CDJ69295.1 - 7.3e-11 41.6 1.6 7.3e-11 41.6 1.1 2.2 2 1 0 2 2 2 1 DnaJ domain OmpH PF03938.9 CDJ69295.1 - 1.3e-06 28.4 1.4 1.3e-06 28.4 1.0 4.4 3 1 0 3 3 3 1 Outer membrane protein (OmpH-like) SR-25 PF10500.4 CDJ69295.1 - 0.0039 16.6 7.9 0.0039 16.6 5.5 5.9 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.3 CDJ69296.1 - 0.045 13.1 6.4 0.58 9.4 1.4 2.1 2 0 0 2 2 2 0 Spt20 family DUF2763 PF10961.3 CDJ69296.1 - 0.083 13.2 0.1 0.083 13.2 0.1 5.5 4 2 2 6 6 6 0 Protein of unknown function (DUF2763) Band_3_cyto PF07565.8 CDJ69296.1 - 0.8 9.1 7.6 0.98 8.8 0.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain RAB3GAP2_N PF14655.1 CDJ69296.1 - 0.88 8.5 10.7 3.8 6.4 3.8 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus APC_CDC26 PF10471.4 CDJ69296.1 - 3 8.6 24.1 2.6 8.8 3.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3371 PF11851.3 CDJ69296.1 - 4.9 7.8 13.6 8 7.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Suf PF05843.9 CDJ69296.1 - 8 6.0 9.8 1.9 8.1 1.8 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ69296.1 - 8.2 5.3 15.5 5.3 6.0 0.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF4613 PF15390.1 CDJ69297.1 - 0.21 9.6 5.8 0.026 12.7 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) Macoilin PF09726.4 CDJ69297.1 - 6.1 5.0 18.5 0.77 7.9 1.7 2.3 2 0 0 2 2 2 0 Transmembrane protein Methyltransf_18 PF12847.2 CDJ69298.1 - 2.9e-10 40.6 0.0 6.5e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ69298.1 - 6.6e-09 35.5 0.0 0.00011 21.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ69298.1 - 1.2e-08 34.8 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ69298.1 - 5.1e-08 33.2 0.1 1.3e-06 28.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ69298.1 - 6.2e-07 29.8 0.1 2.7e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 CDJ69298.1 - 0.002 17.6 0.0 0.0038 16.6 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.1 CDJ69298.1 - 0.0036 17.6 0.2 0.046 14.0 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ69298.1 - 0.012 15.6 2.0 0.11 12.5 1.4 2.4 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CDJ69298.1 - 0.023 13.8 0.1 0.53 9.3 0.0 2.0 1 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 CDJ69298.1 - 0.027 13.4 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ribosomal_60s PF00428.14 CDJ69298.1 - 0.42 11.0 11.0 0.89 10.0 7.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SLX9 PF15341.1 CDJ69299.1 - 2.1e-06 28.1 2.1 2.1e-06 28.1 1.5 2.5 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 RRN9 PF10680.4 CDJ69299.1 - 0.21 11.3 1.2 0.38 10.5 0.9 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor SR-25 PF10500.4 CDJ69300.1 - 0.087 12.2 6.1 0.077 12.4 4.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Collagen PF01391.13 CDJ69301.1 - 0.00012 21.5 29.9 0.00012 21.5 20.7 2.5 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) Macoilin PF09726.4 CDJ69302.1 - 1.7 6.8 7.4 0.078 11.2 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein Ribosomal_S21 PF01165.15 CDJ69303.1 - 7e-05 22.1 0.0 7e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S21 FTCD_C PF04961.7 CDJ69303.1 - 0.00015 21.2 0.2 0.00019 20.9 0.2 1.0 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase Herpes_UL35 PF04496.7 CDJ69303.1 - 4.5 7.5 5.7 0.67 10.1 0.2 2.1 1 1 1 2 2 2 0 Herpesvirus UL35 family UCH PF00443.24 CDJ69304.1 - 2.5e-28 98.9 2.0 3.1e-28 98.6 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDJ69304.1 - 7.2e-13 48.6 0.2 7.2e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HAD PF12710.2 CDJ69304.1 - 0.051 13.7 0.0 0.21 11.7 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PAT1 PF09770.4 CDJ69305.1 - 0.26 9.4 18.5 0.35 9.0 12.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDJ69305.1 - 0.45 10.3 24.6 0.026 14.4 11.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2413 PF10310.4 CDJ69305.1 - 0.46 9.2 11.8 0.71 8.6 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Spore_coat_CotO PF14153.1 CDJ69305.1 - 1.6 8.1 9.9 2.4 7.5 6.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO HlyD_2 PF12700.2 CDJ69305.1 - 1.6 7.7 3.9 2.2 7.3 2.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4045 PF13254.1 CDJ69307.1 - 0.034 13.4 21.7 0.04 13.2 15.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 CDJ69307.1 - 6.4 6.5 24.5 8.3 6.2 17.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dicty_REP PF05086.7 CDJ69307.1 - 7.4 4.1 16.9 8.1 4.0 11.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TP53IP5 PF15331.1 CDJ69308.1 - 0.029 14.3 16.5 0.034 14.0 11.4 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PMSI1 PF15322.1 CDJ69308.1 - 0.33 10.0 21.8 0.37 9.8 15.1 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Asp-B-Hydro_N PF05279.6 CDJ69308.1 - 1.2 8.8 7.6 1.3 8.8 5.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Macoilin PF09726.4 CDJ69308.1 - 1.4 7.1 33.3 1.5 6.9 23.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 CDJ69308.1 - 1.4 7.7 16.4 1.5 7.6 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 CDJ69308.1 - 1.5 8.3 19.2 1.8 8.1 13.3 1.3 1 0 0 1 1 1 0 IncA protein Med15 PF09606.5 CDJ69308.1 - 2.2 6.3 47.5 2.5 6.2 33.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BTV_NS2 PF04514.7 CDJ69308.1 - 2.5 6.9 10.0 2.7 6.7 6.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop25 PF09805.4 CDJ69308.1 - 3.2 7.8 17.8 5.8 6.9 12.3 1.4 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) DDRGK PF09756.4 CDJ69308.1 - 3.4 7.0 16.1 4.2 6.7 11.2 1.2 1 0 0 1 1 1 0 DDRGK domain DUF4175 PF13779.1 CDJ69308.1 - 3.8 5.0 34.5 4.2 4.9 23.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gag_spuma PF03276.9 CDJ69308.1 - 5.4 5.2 41.3 5.9 5.1 28.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein eIF3_subunit PF08597.5 CDJ69308.1 - 6.1 6.3 14.1 7.1 6.1 9.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FemAB PF02388.11 CDJ69308.1 - 9.5 4.7 13.7 11 4.5 9.5 1.1 1 0 0 1 1 1 0 FemAB family DUF2967 PF11179.3 CDJ69309.1 - 0.06 12.8 8.2 0.068 12.6 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) RskA PF10099.4 CDJ69309.1 - 0.93 9.1 14.9 2.3 7.8 10.3 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PAT1 PF09770.4 CDJ69310.1 - 0.1 10.7 103.6 0.13 10.4 71.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 CDJ69311.1 - 0.084 11.4 0.0 0.18 10.3 0.0 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Helicase_C PF00271.26 CDJ69312.1 - 5.3e-17 61.4 0.0 1.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DUF3853 PF12964.2 CDJ69316.1 - 0.023 14.4 1.0 0.023 14.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) PspB PF06667.7 CDJ69316.1 - 0.05 13.5 0.7 0.05 13.5 0.5 2.7 3 0 0 3 3 3 0 Phage shock protein B DUF4407 PF14362.1 CDJ69316.1 - 0.059 12.3 18.7 0.095 11.6 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4577 PF15145.1 CDJ69316.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) DUF2360 PF10152.4 CDJ69316.1 - 1.2 9.3 23.7 2 8.6 16.4 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1510 PF07423.6 CDJ69316.1 - 1.3 8.3 20.0 1.9 7.7 10.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 CDJ69316.1 - 1.8 7.3 11.5 2.8 6.6 8.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 CDJ69316.1 - 3.5 6.8 46.9 6.7 5.9 32.5 1.6 1 1 0 1 1 1 0 SprA-related family PMI_typeI PF01238.16 CDJ69316.1 - 3.7 6.4 13.4 4.8 6.0 9.3 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I phage_tail_N PF08400.5 CDJ69317.1 - 0.11 12.2 2.1 0.14 11.8 1.5 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Ribosomal_60s PF00428.14 CDJ69317.1 - 0.15 12.4 17.3 0.29 11.5 12.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4139 PF13598.1 CDJ69317.1 - 0.2 10.8 8.4 0.26 10.5 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Med3 PF11593.3 CDJ69317.1 - 5.4 6.1 8.0 6.2 5.9 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAF1 PF04857.15 CDJ69320.1 - 1.6e-65 221.0 0.1 2.2e-65 220.6 0.1 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease APG9 PF04109.11 CDJ69321.1 - 4.6e-17 61.9 0.2 6.3e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 AAA_23 PF13476.1 CDJ69322.1 - 0.074 13.3 0.0 0.074 13.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CDJ69323.1 - 1.2e-78 261.7 6.9 8.7e-42 142.4 0.0 4.7 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDJ69323.1 - 1.6e-11 44.5 0.1 1.3e-07 31.7 0.0 6.3 3 2 0 5 5 2 2 AAA ATPase domain AAA_17 PF13207.1 CDJ69323.1 - 2.6e-10 41.1 0.0 0.00094 19.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CDJ69323.1 - 6.6e-10 38.8 0.8 8.5e-05 22.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CDJ69323.1 - 6.8e-10 38.3 0.0 3.9e-05 22.8 0.0 3.4 4 0 0 4 4 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CDJ69323.1 - 2.5e-09 37.3 6.8 0.0029 17.7 0.0 4.8 3 2 0 3 3 3 2 AAA domain AAA_33 PF13671.1 CDJ69323.1 - 5.8e-09 35.9 0.0 6.2e-06 26.1 0.0 5.6 5 1 0 5 5 3 2 AAA domain Bac_DnaA PF00308.13 CDJ69323.1 - 5.5e-08 32.7 0.0 0.00022 20.9 0.0 3.1 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.1 CDJ69323.1 - 5.9e-08 32.6 0.0 0.0013 18.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 CDJ69323.1 - 3.9e-07 29.1 0.2 0.0031 16.3 0.1 2.8 2 1 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 CDJ69323.1 - 5.5e-07 29.7 0.0 0.012 15.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.9 CDJ69323.1 - 3.6e-06 27.0 13.7 0.0072 16.2 0.0 5.0 4 1 1 5 5 4 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CDJ69323.1 - 3.9e-06 26.4 6.6 0.018 14.4 0.0 3.7 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 CDJ69323.1 - 0.00029 21.1 6.2 0.25 11.6 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.1 CDJ69323.1 - 0.00048 20.5 25.3 0.097 12.9 3.4 4.4 5 0 0 5 5 4 2 AAA domain AAA_3 PF07726.6 CDJ69323.1 - 0.00067 19.2 0.0 1.3 8.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CDJ69323.1 - 0.0007 18.7 1.0 1.7 7.7 0.0 3.5 3 1 0 3 3 3 2 KaiC NTPase_1 PF03266.10 CDJ69323.1 - 0.001 18.7 0.3 0.57 9.8 0.0 3.1 2 1 1 3 3 3 1 NTPase AAA_28 PF13521.1 CDJ69323.1 - 0.0015 18.5 0.0 0.049 13.6 0.0 5.2 5 0 0 5 5 3 2 AAA domain UPF0079 PF02367.12 CDJ69323.1 - 0.0043 16.6 0.1 3.1 7.4 0.1 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CDJ69323.1 - 0.0046 16.6 0.1 0.44 10.2 0.0 3.2 2 2 1 3 3 3 1 Archaeal ATPase ABC_tran PF00005.22 CDJ69323.1 - 0.0052 17.0 13.2 0.26 11.5 0.0 4.3 4 0 0 4 4 4 2 ABC transporter NACHT PF05729.7 CDJ69323.1 - 0.0065 16.1 16.5 0.33 10.6 0.0 5.2 5 0 0 5 5 5 2 NACHT domain NB-ARC PF00931.17 CDJ69323.1 - 0.026 13.3 9.3 0.24 10.2 0.0 3.0 3 0 0 3 3 2 0 NB-ARC domain AAA_24 PF13479.1 CDJ69323.1 - 0.038 13.5 9.2 0.47 10.0 0.0 3.7 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 CDJ69323.1 - 0.041 13.7 0.0 0.041 13.7 0.0 4.2 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 CDJ69323.1 - 0.042 13.3 0.1 4 7.0 0.1 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Spt20 PF12090.3 CDJ69323.1 - 0.14 11.4 16.8 0.036 13.4 5.0 2.6 2 0 0 2 2 2 0 Spt20 family Parvo_NS1 PF01057.12 CDJ69323.1 - 0.25 10.1 0.0 0.25 10.1 0.0 3.4 4 0 0 4 4 4 0 Parvovirus non-structural protein NS1 zf-DHHC PF01529.15 CDJ69323.1 - 0.25 10.7 6.4 0.56 9.5 0.9 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase Afi1 PF07792.7 CDJ69323.1 - 4.2 7.3 16.4 1.6 8.7 4.7 2.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SprA-related PF12118.3 CDJ69324.1 - 0.00058 19.2 14.1 0.00058 19.2 9.8 5.5 4 1 1 5 5 5 1 SprA-related family AAA_23 PF13476.1 CDJ69324.1 - 0.056 13.7 0.4 0.056 13.7 0.3 3.8 3 1 0 3 3 3 0 AAA domain Porphobil_deam PF01379.15 CDJ69325.1 - 4.1e-36 123.9 5.2 7.5e-21 74.0 0.0 3.9 3 1 0 3 3 3 3 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CDJ69325.1 - 1.3e-13 50.8 0.4 3.9e-13 49.3 0.2 1.9 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Activator_LAG-3 PF11498.3 CDJ69325.1 - 0.0022 16.8 16.0 0.0022 16.8 11.1 3.3 3 0 0 3 3 3 2 Transcriptional activator LAG-3 Spt20 PF12090.3 CDJ69325.1 - 0.0047 16.3 6.2 0.027 13.8 1.0 2.7 3 0 0 3 3 3 1 Spt20 family Spp-24 PF07448.6 CDJ69325.1 - 0.065 13.1 0.2 0.065 13.1 0.1 2.2 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) Pex16 PF08610.5 CDJ69325.1 - 0.28 10.1 5.2 4.3 6.2 0.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) RAB3GAP2_N PF14655.1 CDJ69325.1 - 0.48 9.3 16.5 0.42 9.5 1.0 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDJ69325.1 - 0.68 8.9 17.1 0.4 9.6 5.8 2.2 2 0 0 2 2 2 0 Fms-interacting protein AAA_23 PF13476.1 CDJ69325.1 - 2.2 8.5 9.3 0.77 10.0 1.0 2.2 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 CDJ69326.1 - 2.2e-44 151.5 0.0 4.1e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69326.1 - 1.1e-19 70.6 0.0 1.7e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ69326.1 - 3.2e-07 29.5 0.0 6.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDJ69326.1 - 0.048 13.3 0.1 0.048 13.3 0.1 2.3 3 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 CDJ69326.1 - 0.052 12.6 0.1 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CDJ69326.1 - 0.14 11.7 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2215 PF10225.4 CDJ69326.1 - 6.1 6.2 6.9 27 4.1 0.4 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2215) Guanylate_cyc PF00211.15 CDJ69328.1 - 1.4e-18 66.8 0.1 2.5e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.26 CDJ69328.1 - 1.9 7.6 5.2 0.25 10.5 0.2 2.0 3 0 0 3 3 3 0 Ion transport protein LRR_4 PF12799.2 CDJ69329.1 - 6.2e-24 83.1 7.0 2.6e-08 33.3 0.0 5.1 2 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ69329.1 - 1.4e-15 56.7 0.1 1.3e-05 24.8 0.1 3.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CDJ69329.1 - 2.3e-10 39.0 8.1 0.036 14.0 0.0 6.7 5 2 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CDJ69329.1 - 3.3e-06 26.4 7.8 5.5 7.6 0.1 7.3 7 1 1 8 8 8 2 Leucine rich repeat LRR_6 PF13516.1 CDJ69329.1 - 1.3e-05 24.7 6.8 24 5.3 0.0 7.3 7 1 1 8 8 8 1 Leucine Rich repeat LRR_9 PF14580.1 CDJ69329.1 - 0.00017 21.2 0.3 0.0042 16.6 0.0 2.6 1 1 2 3 3 3 1 Leucine-rich repeat BOP1NT PF08145.7 CDJ69334.1 - 0.0072 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain Rootletin PF15035.1 CDJ69334.1 - 0.0098 15.8 2.0 0.0098 15.8 1.4 1.6 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF1003 PF06210.6 CDJ69334.1 - 0.05 13.5 2.7 4.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Mgr1 PF08602.5 CDJ69334.1 - 0.068 12.1 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit BAGE PF08180.6 CDJ69335.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 B melanoma antigen family Cation_ATPase_N PF00690.21 CDJ69336.1 - 0.00021 20.6 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 CDJ69337.1 - 4.7e-52 176.3 1.1 1.3e-51 174.8 0.8 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDJ69337.1 - 5.5e-26 92.3 0.0 1.1e-25 91.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ69337.1 - 2.9e-14 53.6 0.0 5.6e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDJ69337.1 - 0.00042 20.2 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDJ69337.1 - 0.00085 18.9 0.1 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase BRF1 PF07741.8 CDJ69337.1 - 4.4 7.5 6.0 9.1 6.5 4.1 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Tubulin PF00091.20 CDJ69338.1 - 1.6e-35 122.9 0.0 2.6e-23 82.9 0.0 2.3 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 CDJ69338.1 - 0.07 12.0 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like RRM_1 PF00076.17 CDJ69339.1 - 3.5e-15 55.3 0.0 7.7e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 CDJ69339.1 - 2.1e-12 46.5 0.1 3.7e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Surp module cwf21 PF08312.7 CDJ69339.1 - 2.8e-11 43.0 4.7 2.8e-11 43.0 3.2 2.6 2 0 0 2 2 2 1 cwf21 domain RRM_5 PF13893.1 CDJ69339.1 - 4.4e-08 32.8 0.0 8.8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ69339.1 - 3.9e-07 29.9 0.1 1.2e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 CDJ69339.1 - 0.023 14.3 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 ATP-synt_Eps PF04627.8 CDJ69340.1 - 9e-09 34.7 0.1 1.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ribosomal_60s PF00428.14 CDJ69343.1 - 0.38 11.1 9.3 0.34 11.3 2.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C48 PF02902.14 CDJ69345.1 - 0.023 14.3 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain MORN PF02493.15 CDJ69347.1 - 1.4e-12 46.5 11.9 6.6e-05 22.4 0.1 5.4 5 0 0 5 5 5 4 MORN repeat AP2 PF00847.15 CDJ69347.1 - 0.055 13.6 0.2 0.055 13.6 0.1 3.0 4 0 0 4 4 4 0 AP2 domain Folate_rec PF03024.9 CDJ69348.1 - 9e-14 51.4 13.1 1.2e-13 51.0 9.1 1.2 1 0 0 1 1 1 1 Folate receptor family IMS PF00817.15 CDJ69349.1 - 1.3e-38 132.1 1.6 2.4e-38 131.2 0.3 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 CDJ69349.1 - 6.4e-14 51.9 0.4 3e-13 49.8 0.2 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CDJ69349.1 - 0.00034 20.4 0.0 0.00077 19.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.3 CDJ69349.1 - 0.0099 15.7 0.1 0.041 13.8 0.0 2.0 2 0 0 2 2 2 1 Pathogenicity locus GTP1_OBG PF01018.17 CDJ69351.1 - 3.1e-22 78.9 1.8 1.7e-12 47.2 0.2 2.5 2 0 0 2 2 2 2 GTP1/OBG GTP_EFTU PF00009.22 CDJ69351.1 - 7e-09 35.3 0.0 4e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDJ69351.1 - 1.9e-07 31.0 0.0 1.6e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CDJ69351.1 - 3.8e-06 26.4 0.1 0.049 13.1 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CDJ69351.1 - 3.2e-05 24.3 0.1 0.61 10.5 0.0 3.4 4 0 0 4 4 3 2 Miro-like protein Arf PF00025.16 CDJ69351.1 - 0.001 18.3 0.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 CDJ69351.1 - 0.005 16.4 0.0 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CDJ69351.1 - 0.026 13.9 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 CDJ69351.1 - 0.034 13.9 1.7 0.065 13.0 0.1 2.4 2 1 0 2 2 2 0 Dynamin family G-alpha PF00503.15 CDJ69351.1 - 0.06 12.0 1.0 5.7 5.5 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit AAA_29 PF13555.1 CDJ69351.1 - 0.073 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 CDJ69351.1 - 0.12 11.7 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Ras family DUF1967 PF09269.6 CDJ69351.1 - 0.23 11.1 0.0 0.55 9.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) AAA_23 PF13476.1 CDJ69351.1 - 0.97 9.7 0.0 0.97 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain ParB PF08775.5 CDJ69354.1 - 0.054 13.8 5.6 0.15 12.3 2.4 2.5 2 0 0 2 2 2 0 ParB family Epimerase PF01370.16 CDJ69355.1 - 4.7e-40 137.4 0.0 6.9e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDJ69355.1 - 0.00025 20.0 0.0 0.00041 19.3 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CDJ69355.1 - 0.00096 17.9 0.0 0.0043 15.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CDJ69355.1 - 0.015 14.1 0.6 0.066 12.1 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 CDJ69355.1 - 0.054 12.3 0.1 0.18 10.6 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein BBS2_Mid PF14783.1 CDJ69355.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region TIP49 PF06068.8 CDJ69356.1 - 5.4e-132 440.2 4.7 1.2e-115 386.4 0.0 2.0 2 0 0 2 2 2 2 TIP49 C-terminus AAA_22 PF13401.1 CDJ69356.1 - 0.044 13.9 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 CDJ69357.1 - 3.6e-07 29.7 0.0 5.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PT PF04886.7 CDJ69357.1 - 1.1e-06 27.7 18.3 5.3e-05 22.4 6.2 3.6 2 1 1 3 3 3 2 PT repeat RRM_6 PF14259.1 CDJ69357.1 - 3.2e-05 23.8 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Corona_nucleoca PF00937.13 CDJ69357.1 - 0.0012 17.9 10.4 0.0012 17.9 7.2 2.3 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein FAD-oxidase_C PF02913.14 CDJ69357.1 - 1.9 7.7 7.6 0.065 12.5 0.4 1.9 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain CoA_transf_3 PF02515.12 CDJ69357.1 - 5.1 6.2 8.5 0.077 12.2 0.7 1.8 2 0 0 2 2 2 0 CoA-transferase family III DUF966 PF06136.8 CDJ69357.1 - 6.5 6.0 11.4 7.9 5.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) U79_P34 PF03064.11 CDJ69357.1 - 8.4 5.8 15.5 17 4.8 10.7 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4303 PF14136.1 CDJ69358.1 - 0.9 9.1 5.5 0.56 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) CTP_transf_1 PF01148.15 CDJ69362.1 - 6.4e-15 55.5 5.7 4.8e-14 52.6 3.9 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family CAF-1_p150 PF11600.3 CDJ69363.1 - 0.13 11.6 13.1 0.21 10.9 9.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal VESA1_N PF12785.2 CDJ69363.1 - 3.4 6.5 13.6 8.2 5.2 9.5 1.5 2 0 0 2 2 2 0 Variant erythrocyte surface antigen-1 DUF4614 PF15391.1 CDJ69363.1 - 4.2 7.0 10.4 7.6 6.2 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Corona_nucleoca PF00937.13 CDJ69363.1 - 5 5.9 11.4 7.8 5.3 7.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SprA-related PF12118.3 CDJ69364.1 - 0.0045 16.3 24.4 0.0045 16.3 16.9 3.9 3 1 0 3 3 3 1 SprA-related family Tim54 PF11711.3 CDJ69364.1 - 1.1 7.8 12.8 2.6 6.5 1.6 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.4 CDJ69364.1 - 1.4 7.0 82.7 1 7.5 23.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.1 CDJ69364.1 - 9.7 5.0 38.1 4.5 6.1 7.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1517 PF07466.6 CDJ69365.1 - 1.2 8.0 5.5 2.8 6.8 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Aldedh PF00171.17 CDJ69366.1 - 2.7e-139 464.4 4.1 1.2e-136 455.7 2.9 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CDJ69366.1 - 0.038 12.7 0.2 0.48 9.0 0.2 2.0 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DNA_methylase PF00145.12 CDJ69368.1 - 6.2e-18 65.0 4.1 5.4e-08 32.3 0.0 4.4 5 0 0 5 5 5 4 C-5 cytosine-specific DNA methylase PHD PF00628.24 CDJ69369.1 - 7.8e-10 38.2 9.3 7.8e-10 38.2 6.5 2.5 2 0 0 2 2 1 1 PHD-finger zf-RING_2 PF13639.1 CDJ69369.1 - 2.1e-07 30.6 11.5 2.1e-07 30.6 8.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CDJ69369.1 - 2.8e-05 24.1 5.1 2.8e-05 24.1 3.5 2.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CDJ69369.1 - 4.2e-05 23.1 7.4 4.2e-05 23.1 5.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ69369.1 - 0.00023 21.1 12.5 0.00023 21.1 8.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ69369.1 - 0.00045 19.8 9.3 0.00045 19.8 6.4 2.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDJ69369.1 - 0.00098 18.7 11.7 0.00098 18.7 8.1 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 CDJ69369.1 - 0.003 16.8 4.0 0.0085 15.3 2.8 1.9 1 0 0 1 1 1 1 PHD-finger Baculo_IE-1 PF05290.6 CDJ69369.1 - 0.011 15.4 2.7 0.026 14.2 1.9 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Apc11 PF12861.2 CDJ69369.1 - 0.05 13.4 11.6 1 9.2 2.1 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CDJ69369.1 - 0.072 12.8 6.7 0.27 10.9 4.6 2.1 1 0 0 1 1 1 0 RING-type zinc-finger Prp19_bind PF06991.6 CDJ69370.1 - 0.01 15.1 18.3 0.013 14.7 12.7 1.3 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF1168 PF06658.7 CDJ69370.1 - 0.076 12.5 44.5 0.026 14.0 20.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF334 PF03904.8 CDJ69370.1 - 1.6 7.9 14.1 2.1 7.6 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) AATF-Che1 PF13339.1 CDJ69370.1 - 2.8 8.1 26.3 0.18 11.9 9.7 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF2422 PF10337.4 CDJ69370.1 - 2.9 6.5 9.9 3.6 6.2 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF4603 PF15376.1 CDJ69370.1 - 9.1 3.3 33.6 11 3.0 23.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Peptidase_S8 PF00082.17 CDJ69371.1 - 2.4e-25 89.2 0.3 2.4e-25 89.2 0.2 3.8 2 2 1 3 3 3 1 Subtilase family AAA_22 PF13401.1 CDJ69371.1 - 5e-05 23.4 0.9 0.024 14.7 0.0 3.3 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.22 CDJ69371.1 - 0.009 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF2791 PF10923.3 CDJ69371.1 - 0.012 14.2 0.0 0.026 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) DUF2075 PF09848.4 CDJ69371.1 - 0.033 13.1 0.1 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 CDJ69371.1 - 0.04 12.7 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 CDJ69371.1 - 0.23 11.0 4.9 3.7 7.1 3.4 2.6 1 1 0 1 1 1 0 NACHT domain Carboxyl_trans PF01039.17 CDJ69373.1 - 8.6e-148 492.7 0.0 1.1e-146 489.1 0.0 2.1 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CDJ69373.1 - 1.9e-52 177.6 0.0 3.5e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ACC_central PF08326.7 CDJ69373.1 - 3.9e-26 91.4 2.3 1.5e-20 72.9 0.9 3.1 2 1 0 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_chain PF00289.17 CDJ69373.1 - 3e-24 85.2 0.0 6.5e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CDJ69373.1 - 1.4e-20 73.2 0.0 3.6e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CDJ69373.1 - 3.5e-17 62.7 0.0 1.3e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CDJ69373.1 - 3.1e-10 39.5 0.0 8.4e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.17 CDJ69373.1 - 1.5e-08 34.2 0.0 3.2e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CDJ69373.1 - 1.7e-06 27.5 0.0 3.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CDJ69373.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CDJ69373.1 - 0.0026 17.3 0.1 0.014 15.0 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.14 CDJ69373.1 - 0.12 12.0 0.0 0.89 9.2 0.0 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein RimK PF08443.6 CDJ69373.1 - 0.15 11.5 0.0 0.36 10.2 0.0 1.6 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_2 PF12700.2 CDJ69373.1 - 0.15 11.1 0.5 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein Chorein_N PF12624.2 CDJ69374.1 - 2.4e-31 107.6 0.0 6.5e-31 106.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CDJ69374.1 - 1.3e-07 31.0 0.0 4.8e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Plasmodium_Vir PF05795.6 CDJ69374.1 - 0.18 10.9 0.4 0.5 9.5 0.3 1.7 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ribosomal_L11_N PF03946.9 CDJ69375.1 - 1.3e-16 59.8 0.0 1.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CDJ69375.1 - 2.3e-13 50.0 0.1 3.7e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain TM231 PF10149.4 CDJ69375.1 - 0.025 13.5 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 Ribosomal_L30 PF00327.15 CDJ69376.1 - 7.5e-16 57.4 0.5 1.4e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CDJ69376.1 - 6.2e-14 51.7 19.0 1.3e-13 50.7 13.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain zf-RING_2 PF13639.1 CDJ69378.1 - 2.5e-08 33.6 7.3 8.1e-07 28.7 2.2 2.5 2 0 0 2 2 2 2 Ring finger domain WWE PF02825.15 CDJ69378.1 - 8.6e-07 28.2 2.7 0.063 12.7 0.1 3.6 3 1 0 3 3 3 2 WWE domain zf-rbx1 PF12678.2 CDJ69378.1 - 2.7e-06 27.3 7.0 0.00015 21.7 1.3 2.8 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDJ69378.1 - 0.00031 20.3 4.7 0.00031 20.3 3.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CDJ69378.1 - 0.001 18.7 2.4 0.0034 17.0 1.7 1.9 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 CDJ69378.1 - 0.0021 17.7 5.5 0.0032 17.1 2.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDJ69378.1 - 0.0077 16.2 8.5 0.017 15.0 2.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDJ69378.1 - 0.039 13.7 0.5 0.039 13.7 0.4 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Caudo_TAP PF02413.12 CDJ69378.1 - 0.53 10.4 8.2 0.27 11.4 3.7 1.9 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein zf-C3HC4_4 PF15227.1 CDJ69378.1 - 0.93 9.4 8.5 0.43 10.5 3.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Ribosomal_S19e PF01090.14 CDJ69379.1 - 2e-50 169.8 0.0 2.2e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.5 CDJ69379.1 - 0.0017 18.0 0.3 0.0033 17.0 0.1 1.6 2 0 0 2 2 2 1 Ribonuclease R winged-helix domain AP_endonuc_2 PF01261.19 CDJ69380.1 - 3.1e-16 59.3 0.0 5.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel NAGLU PF05089.7 CDJ69382.1 - 0.17 10.5 3.0 0.29 9.8 2.1 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain ECH PF00378.15 CDJ69383.1 - 5.4e-29 101.0 7.0 1.1e-21 77.1 7.3 2.5 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Spc97_Spc98 PF04130.8 CDJ69384.1 - 1.6e-16 59.7 11.4 1.6e-15 56.4 7.9 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family Band_3_cyto PF07565.8 CDJ69384.1 - 0.023 14.2 4.8 0.1 12.0 0.9 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SGT1 PF07093.6 CDJ69384.1 - 0.03 12.6 5.3 0.98 7.7 0.2 2.1 2 0 0 2 2 2 0 SGT1 protein DUF2722 PF10846.3 CDJ69384.1 - 0.047 12.7 4.7 1.4 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2791 PF10923.3 CDJ69384.1 - 0.096 11.2 7.2 0.01 14.4 2.0 1.5 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) RAB3GAP2_N PF14655.1 CDJ69384.1 - 0.55 9.1 12.6 0.48 9.3 0.7 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Peptidase_S30 PF01577.11 CDJ69384.1 - 0.71 9.2 5.1 2.5 7.4 0.2 2.3 2 0 0 2 2 2 0 Potyvirus P1 protease TMEM51 PF15345.1 CDJ69384.1 - 0.88 9.2 9.5 0.82 9.3 0.3 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 Hairy_orange PF07527.8 CDJ69385.1 - 0.13 12.0 1.3 0.48 10.2 0.6 2.2 2 0 0 2 2 2 0 Hairy Orange Spt20 PF12090.3 CDJ69385.1 - 0.2 10.9 17.2 3.3 7.0 3.4 3.2 3 0 0 3 3 3 0 Spt20 family Med15 PF09606.5 CDJ69385.1 - 0.33 9.1 81.5 0.061 11.5 17.3 3.5 3 1 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ69385.1 - 4.7 6.8 17.8 18 4.9 0.2 3.2 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Hus1 PF04005.7 CDJ69386.1 - 2.2e-12 46.5 0.0 2.5e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Mob1_phocein PF03637.12 CDJ69387.1 - 1.1e-18 67.4 0.2 2.4e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 Mob1/phocein family DUF4613 PF15390.1 CDJ69387.1 - 0.96 7.5 12.5 1.3 7.1 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) WD40 PF00400.27 CDJ69388.1 - 1.5e-62 205.4 6.9 4.3e-14 51.7 0.2 9.6 8 1 0 8 8 8 7 WD domain, G-beta repeat NLE PF08154.7 CDJ69388.1 - 0.0016 18.3 0.1 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CDJ69388.1 - 0.024 14.3 0.0 0.099 12.3 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ndc1_Nup PF09531.5 CDJ69389.1 - 0.25 9.6 10.7 7 4.9 7.4 2.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DEAD PF00270.24 CDJ69390.1 - 1.8e-20 73.0 0.0 6.4e-10 38.7 0.0 3.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ69390.1 - 9.5e-20 70.2 0.1 9.5e-20 70.2 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDJ69390.1 - 0.0015 18.4 0.0 0.0015 18.4 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SPX PF03105.14 CDJ69390.1 - 0.039 13.7 26.8 0.049 13.4 0.9 2.3 2 0 0 2 2 2 0 SPX domain SAPS PF04499.10 CDJ69390.1 - 0.31 9.6 19.6 0.16 10.5 8.3 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SOBP PF15279.1 CDJ69390.1 - 0.62 10.3 29.8 2.6 8.3 2.6 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Mem_trans PF03547.13 CDJ69390.1 - 0.82 7.9 14.0 0.048 11.9 0.3 2.2 2 0 0 2 2 2 0 Membrane transport protein SAGA-Tad1 PF12767.2 CDJ69390.1 - 2.5 7.7 36.7 0.077 12.6 15.6 2.7 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit LMBR1 PF04791.11 CDJ69390.1 - 6.7 5.1 11.7 0.012 14.2 1.1 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF966 PF06136.8 CDJ69390.1 - 8.3 5.7 33.2 2.5 7.4 3.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Alpha_GJ PF03229.8 CDJ69391.1 - 1 9.7 26.5 0.15 12.3 5.8 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J MxiH PF09392.5 CDJ69391.1 - 1.6 9.3 9.0 0.14 12.7 0.2 2.4 2 0 0 2 2 2 0 Type III secretion needle MxiH like Robl_LC7 PF03259.12 CDJ69392.1 - 6.3e-24 83.3 0.2 7.7e-24 83.0 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain XRN_N PF03159.13 CDJ69392.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Abhydrolase_5 PF12695.2 CDJ69393.1 - 5.6e-10 39.1 0.0 3.7e-09 36.4 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ69393.1 - 0.00023 21.0 0.0 0.0004 20.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CDJ69393.1 - 0.0054 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CDJ69393.1 - 0.017 14.3 0.1 0.035 13.3 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family DivIC PF04977.10 CDJ69393.1 - 2.2 7.8 9.3 4.3 6.9 6.5 1.4 1 0 0 1 1 1 0 Septum formation initiator DnaJ PF00226.26 CDJ69394.1 - 4.1e-08 32.8 0.0 5.1e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CDJ69394.1 - 2.1e-05 24.3 0.0 2.4e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Pam16 SR-25 PF10500.4 CDJ69395.1 - 0.046 13.1 28.7 0.069 12.6 19.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Shadoo PF14999.1 CDJ69395.1 - 1 9.2 13.1 3.8 7.3 7.7 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF1632 PF07857.7 CDJ69395.1 - 2.8 7.1 4.6 4.2 6.5 3.2 1.2 1 0 0 1 1 1 0 CEO family (DUF1632) DUF3552 PF12072.3 CDJ69396.1 - 0.00096 18.4 39.2 0.00096 18.4 27.2 12.9 6 1 8 14 14 14 2 Domain of unknown function (DUF3552) DUF2981 PF11200.3 CDJ69396.1 - 1.3 8.0 1.7 14 4.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Pkinase PF00069.20 CDJ69398.1 - 7.4e-07 28.5 0.1 1.9e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69398.1 - 0.00012 21.2 0.1 0.00028 20.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase TMEM164 PF14808.1 CDJ69398.1 - 0.0044 16.2 0.1 0.0073 15.5 0.1 1.2 1 0 0 1 1 1 1 TMEM164 family DUF3304 PF11745.3 CDJ69398.1 - 0.014 15.5 0.1 0.037 14.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) RAB3GAP2_N PF14655.1 CDJ69398.1 - 0.021 13.8 1.8 0.031 13.3 1.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.3 CDJ69398.1 - 0.022 14.0 0.2 0.031 13.6 0.2 1.2 1 0 0 1 1 1 0 Spt20 family Sex_peptide PF08138.6 CDJ69398.1 - 0.036 13.9 4.3 1.2 9.0 0.4 2.5 1 1 1 2 2 2 0 Sex peptide (SP) family Activator_LAG-3 PF11498.3 CDJ69398.1 - 0.096 11.4 17.4 0.012 14.3 9.4 1.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pyridoxal_deC PF00282.14 CDJ69398.1 - 0.32 9.3 1.5 0.45 8.8 1.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain FxsA PF04186.8 CDJ69398.1 - 1.6 8.3 6.3 3 7.4 4.4 1.4 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein DivIC PF04977.10 CDJ69398.1 - 8.9 5.8 12.8 21 4.7 8.9 1.5 1 0 0 1 1 1 0 Septum formation initiator Trypan_glycop_C PF10659.4 CDJ69399.1 - 0.64 10.3 10.0 0.65 10.3 7.0 1.0 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain XisI PF08869.6 CDJ69399.1 - 2.5 8.2 6.7 2.5 8.2 4.7 1.0 1 0 0 1 1 1 0 XisI protein DUF3469 PF11952.3 CDJ69399.1 - 2.7 7.7 7.3 2.6 7.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) DUF912 PF06024.7 CDJ69399.1 - 4.7 7.3 6.9 4.9 7.2 4.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S49_N PF08496.5 CDJ69399.1 - 7 6.4 7.7 6.9 6.4 5.3 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal tRNA-synt_1g PF09334.6 CDJ69400.1 - 7.3e-06 24.8 0.2 7.3e-06 24.8 0.1 4.1 4 1 0 4 4 4 2 tRNA synthetases class I (M) DUF814 PF05670.8 CDJ69402.1 - 3.1e-19 68.6 0.0 5.2e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Phage_hub_GP28 PF11110.3 CDJ69402.1 - 0.0054 16.4 0.0 0.36 10.5 0.0 2.2 2 0 0 2 2 2 1 Baseplate hub distal subunit Atg14 PF10186.4 CDJ69402.1 - 0.48 9.3 10.5 0.6 8.9 7.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3154 PF11351.3 CDJ69402.1 - 0.66 9.7 3.6 1.2 8.8 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) AAA_23 PF13476.1 CDJ69402.1 - 2.4 8.4 8.5 3.2 8.0 5.9 1.2 1 0 0 1 1 1 0 AAA domain LZ_Tnp_IS66 PF13007.2 CDJ69403.1 - 0.29 11.8 2.7 0.54 10.9 1.9 1.3 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain SR-25 PF10500.4 CDJ69404.1 - 3.6e-05 23.3 8.8 3.6e-05 23.3 6.1 9.8 9 1 2 11 11 11 3 Nuclear RNA-splicing-associated protein SET PF00856.23 CDJ69404.1 - 0.0058 16.9 0.0 0.0058 16.9 0.0 5.2 6 1 0 6 6 6 1 SET domain Arrestin_N PF00339.24 CDJ69404.1 - 2 8.2 8.8 1.5 8.5 0.1 3.4 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain PseudoU_synth_1 PF01416.15 CDJ69406.1 - 2.3e-07 31.1 11.9 0.027 14.8 0.0 3.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase SAPS PF04499.10 CDJ69406.1 - 0.00061 18.5 27.1 0.0016 17.1 10.4 2.3 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.3 CDJ69406.1 - 0.16 11.3 72.1 0.11 11.8 8.6 3.1 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Otopetrin PF03189.8 CDJ69406.1 - 9.6 5.0 11.1 0.97 8.3 3.4 2.1 2 0 0 2 2 2 0 Otopetrin AAA PF00004.24 CDJ69407.1 - 2.2e-13 50.5 0.0 8.3e-13 48.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CDJ69407.1 - 0.0013 18.8 0.0 0.0047 17.0 0.0 1.9 2 0 0 2 2 2 1 FtsH Extracellular Asp_protease_2 PF13650.1 CDJ69408.1 - 3.8e-10 40.1 0.0 9.2e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ69408.1 - 2.9e-08 33.4 0.0 6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ69408.1 - 1.1e-06 28.4 0.0 3.8e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ69408.1 - 5e-05 23.2 0.0 0.00017 21.5 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ69408.1 - 0.0037 16.8 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 CDJ69408.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) FAM92 PF06730.6 CDJ69409.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 FAM92 protein DUF3038 PF11237.3 CDJ69409.1 - 0.052 13.3 0.1 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) rve PF00665.21 CDJ69410.1 - 7.3e-12 45.4 0.1 8e-12 45.3 0.1 1.0 1 0 0 1 1 1 1 Integrase core domain VRR_NUC PF08774.6 CDJ69411.1 - 1e-12 47.9 5.9 2.7e-08 33.7 1.1 3.3 2 0 0 2 2 2 2 VRR-NUC domain Na_trans_assoc PF06512.8 CDJ69411.1 - 0.006 16.5 1.7 0.006 16.5 1.2 6.4 4 1 1 6 6 6 2 Sodium ion transport-associated SDA1 PF05285.7 CDJ69412.1 - 0.048 12.9 9.4 0.058 12.6 6.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 CDJ69412.1 - 0.22 10.5 8.8 0.26 10.2 6.1 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CDJ69412.1 - 6.4 4.5 12.4 7.7 4.3 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CDJ69412.1 - 9.2 4.6 11.8 11 4.3 8.2 1.1 1 0 0 1 1 1 0 Daxx Family Med15 PF09606.5 CDJ69413.1 - 0.94 7.5 52.5 1.5 6.9 36.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF677 PF05055.7 CDJ69414.1 - 0.72 8.4 6.0 1.2 7.7 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Pkinase PF00069.20 CDJ69416.1 - 1.1e-08 34.5 0.0 6.8e-06 25.4 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Gti1_Pac2 PF09729.4 CDJ69416.1 - 7.6 6.3 8.2 45 3.8 3.9 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family K_channel_TID PF07941.6 CDJ69417.1 - 0.01 16.0 10.4 0.01 16.0 7.2 7.5 5 3 2 7 7 7 0 Potassium channel Kv1.4 tandem inactivation domain FXa_inhibition PF14670.1 CDJ69418.1 - 6.1e-21 74.2 29.3 3.6e-11 42.9 2.8 4.1 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CDJ69418.1 - 7.3e-18 63.8 15.7 7.6e-07 28.6 0.0 4.5 4 0 0 4 4 4 4 Complement Clr-like EGF-like EGF_CA PF07645.10 CDJ69418.1 - 6.1e-15 54.9 23.0 3.9e-06 26.7 2.0 3.7 3 0 0 3 3 3 3 Calcium-binding EGF domain EGF PF00008.22 CDJ69418.1 - 3.5e-11 42.8 25.3 0.00027 20.8 0.5 4.2 4 1 0 4 4 4 3 EGF-like domain EGF_3 PF12947.2 CDJ69418.1 - 4.2e-06 26.6 17.7 0.0084 16.0 1.7 3.5 3 0 0 3 3 3 3 EGF domain hEGF PF12661.2 CDJ69418.1 - 0.044 13.8 10.4 8.7 6.6 0.3 3.6 3 0 0 3 3 3 0 Human growth factor-like EGF GBP_PSP PF02425.10 CDJ69418.1 - 0.13 11.8 4.7 0.2 11.2 0.3 2.5 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide EGF_MSP1_1 PF12946.2 CDJ69418.1 - 0.63 9.8 8.0 2.9 7.7 0.1 3.4 3 0 0 3 3 3 0 MSP1 EGF domain 1 Med15 PF09606.5 CDJ69419.1 - 0.35 8.9 66.9 0.45 8.6 46.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1183 PF06682.7 CDJ69419.1 - 1 8.8 12.6 1.3 8.6 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4045 PF13254.1 CDJ69419.1 - 1.1 8.5 22.4 1.3 8.2 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDJ69419.1 - 1.3 7.1 53.2 1.5 6.9 36.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDJ69419.1 - 2 5.9 22.2 2.3 5.7 15.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_Ag35 PF03286.9 CDJ69419.1 - 4.4 6.7 17.8 6.1 6.3 12.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GAGA_bind PF06217.7 CDJ69419.1 - 6.3 6.6 20.1 7.9 6.3 13.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ribosomal_60s PF00428.14 CDJ69420.1 - 1.2 9.5 21.7 1.3 9.4 4.7 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DNA_pol_B_palm PF14792.1 CDJ69421.1 - 3.5e-13 49.5 0.2 6.6e-11 42.2 0.0 3.7 4 0 0 4 4 4 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 CDJ69421.1 - 5.7e-13 48.3 0.0 9.3e-12 44.4 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 CDJ69421.1 - 2.9e-09 36.9 1.7 2.6e-08 33.9 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CDJ69421.1 - 6.3e-05 22.4 1.0 0.00028 20.3 0.7 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH PF00633.18 CDJ69421.1 - 0.0031 17.1 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif UBN2_3 PF14244.1 CDJ69421.1 - 0.29 10.6 1.1 0.76 9.3 0.8 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DEAD PF00270.24 CDJ69422.1 - 1.7e-14 53.6 0.5 1.7e-14 53.6 0.4 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CDJ69422.1 - 0.00031 20.6 0.3 0.00067 19.5 0.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CDJ69422.1 - 0.00076 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CDJ69422.1 - 0.016 14.7 0.1 0.016 14.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 CDJ69422.1 - 0.054 13.1 0.4 0.082 12.5 0.0 1.5 2 0 0 2 2 2 0 Helicase PhoH PF02562.11 CDJ69422.1 - 0.088 12.0 0.1 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Med3 PF11593.3 CDJ69422.1 - 0.14 11.4 2.9 0.19 10.9 2.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_11 PF13086.1 CDJ69422.1 - 0.18 11.3 0.9 0.38 10.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain BAF1_ABF1 PF04684.8 CDJ69423.1 - 0.0001 21.3 12.1 0.0001 21.3 8.4 23.8 17 3 7 25 25 25 5 BAF1 / ABF1 chromatin reorganising factor DUF4232 PF14016.1 CDJ69424.1 - 0.012 15.2 3.4 0.014 15.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) FCP1_C PF09309.5 CDJ69424.1 - 0.04 13.2 9.3 0.043 13.1 6.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Sporozoite_P67 PF05642.6 CDJ69424.1 - 0.079 10.8 3.0 0.086 10.7 2.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Bac_transf PF02397.11 CDJ69424.1 - 0.09 11.8 2.6 0.1 11.7 1.8 1.1 1 0 0 1 1 1 0 Bacterial sugar transferase Dehydrin PF00257.14 CDJ69424.1 - 0.67 10.2 9.8 1.1 9.6 6.8 1.3 1 0 0 1 1 1 0 Dehydrin SR-25 PF10500.4 CDJ69424.1 - 0.93 8.9 21.6 1.4 8.3 15.0 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spc7_N PF15402.1 CDJ69424.1 - 0.95 7.3 12.9 1 7.2 8.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CIAPIN1 PF05093.8 CDJ69424.1 - 1.4 9.0 8.8 2.6 8.1 6.1 1.5 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CDK2AP PF09806.4 CDJ69424.1 - 1.6 8.9 17.8 1.8 8.7 12.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.6 CDJ69424.1 - 2.6 7.3 14.0 2.7 7.2 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) FAM60A PF15396.1 CDJ69424.1 - 2.9 7.5 10.4 3 7.5 7.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A NABP PF07990.7 CDJ69424.1 - 4.3 6.4 15.0 4.4 6.4 10.4 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Scs3p PF10261.4 CDJ69424.1 - 6.4 5.7 6.6 7 5.6 4.6 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Lin-8 PF03353.10 CDJ69424.1 - 7.4 5.7 14.2 7.8 5.6 9.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.4 CDJ69424.1 - 8 4.6 12.4 8.4 4.5 8.6 1.0 1 0 0 1 1 1 0 Transmembrane protein P12 PF12669.2 CDJ69425.1 - 0.015 15.4 9.5 1.9 8.7 2.7 3.9 3 0 0 3 3 3 0 Virus attachment protein p12 family SMC_hinge PF06470.8 CDJ69426.1 - 5.4e-11 42.5 0.0 5.4e-11 42.5 0.0 2.8 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain FliJ PF02050.11 CDJ69426.1 - 1.5 8.9 80.3 1 9.3 17.0 3.3 1 1 2 3 3 3 0 Flagellar FliJ protein Ribosomal_L12 PF00542.14 CDJ69426.1 - 1.9 8.5 8.5 15 5.6 0.9 3.0 1 1 1 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain HHH_7 PF14635.1 CDJ69427.1 - 9.5e-09 35.3 0.0 3.1e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CDJ69427.1 - 2.5e-05 24.2 0.1 9.5e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SR-25 PF10500.4 CDJ69427.1 - 8.3e-05 22.1 8.2 8.3e-05 22.1 5.7 12.0 10 2 1 12 12 12 3 Nuclear RNA-splicing-associated protein FAM92 PF06730.6 CDJ69428.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 FAM92 protein zf-CCCH PF00642.19 CDJ69429.1 - 5.4e-10 38.7 12.8 8.2e-07 28.5 0.7 3.8 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAT1 PF09770.4 CDJ69430.1 - 0.25 9.5 30.2 0.33 9.1 20.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ69430.1 - 0.42 8.7 36.7 0.56 8.3 25.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ69430.1 - 4 7.2 18.8 5.5 6.7 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exo_endo_phos PF03372.18 CDJ69431.1 - 2.4e-19 70.2 0.0 3.9e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CDP-OH_P_transf PF01066.16 CDJ69432.1 - 5.7e-09 36.1 18.4 5.9e-08 32.9 12.7 3.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Skp1 PF01466.14 CDJ69433.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Skp1 family, dimerisation domain FimP PF09766.4 CDJ69434.1 - 0.0012 18.0 12.9 0.0012 18.0 9.0 2.4 2 0 0 2 2 2 2 Fms-interacting protein DUF3306 PF11748.3 CDJ69434.1 - 0.023 15.3 8.4 0.023 15.3 5.8 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF3306) DUF1632 PF07857.7 CDJ69434.1 - 0.33 10.1 2.4 0.17 11.0 0.3 1.6 2 0 0 2 2 2 0 CEO family (DUF1632) DUF2828 PF11443.3 CDJ69434.1 - 0.61 8.2 17.0 1.5 6.8 11.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2828) Drc1-Sld2 PF11719.3 CDJ69434.1 - 0.78 8.7 21.2 1.3 8.0 14.7 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein OATP PF03137.15 CDJ69434.1 - 0.91 7.4 13.6 0.038 12.0 3.9 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CD20 PF04103.10 CDJ69434.1 - 2.4 8.0 7.0 3.3 7.6 1.1 2.3 2 0 0 2 2 2 0 CD20-like family FAM176 PF14851.1 CDJ69434.1 - 2.7 7.6 12.1 0.61 9.7 4.7 2.1 2 0 0 2 2 2 0 FAM176 family DUF605 PF04652.11 CDJ69434.1 - 2.8 7.2 31.2 0.65 9.3 10.3 2.1 2 0 0 2 2 2 0 Vta1 like G0-G1_switch_2 PF15103.1 CDJ69434.1 - 4.3 7.6 21.5 0.65 10.2 6.5 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 AvrE PF11725.3 CDJ69434.1 - 4.5 4.1 29.1 5.7 3.8 20.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor SMN PF06003.7 CDJ69434.1 - 6.7 5.7 11.4 10 5.1 7.9 1.3 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) Peptidase_S64 PF08192.6 CDJ69434.1 - 8.1 4.6 17.7 11 4.2 12.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF3408 PF11888.3 CDJ69434.1 - 9.4 6.1 21.6 7 6.5 9.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Med15 PF09606.5 CDJ69434.1 - 9.6 4.2 68.6 15 3.5 47.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ETRAMP PF09716.5 CDJ69435.1 - 0.0018 18.1 0.2 0.24 11.4 0.0 2.8 2 0 0 2 2 2 2 Malarial early transcribed membrane protein (ETRAMP) Med15 PF09606.5 CDJ69436.1 - 0.0017 16.6 49.3 0.0017 16.6 34.2 1.3 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal zf-DHHC PF01529.15 CDJ69436.1 - 0.0055 16.1 0.2 0.0055 16.1 0.2 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase AAA_23 PF13476.1 CDJ69436.1 - 0.014 15.6 9.6 0.016 15.5 6.6 1.1 1 0 0 1 1 1 0 AAA domain NMDAR2_C PF10565.4 CDJ69436.1 - 0.15 10.7 12.5 0.17 10.5 8.7 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus IncA PF04156.9 CDJ69436.1 - 0.16 11.5 19.7 0.33 10.5 13.7 1.5 1 0 0 1 1 1 0 IncA protein Serinc PF03348.10 CDJ69436.1 - 0.26 9.9 10.8 0.32 9.6 7.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) FLO_LFY PF01698.11 CDJ69436.1 - 0.26 10.0 23.4 0.37 9.5 16.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FimP PF09766.4 CDJ69436.1 - 0.35 9.9 27.3 1.8 7.5 19.5 1.7 2 0 0 2 2 2 0 Fms-interacting protein Ndc1_Nup PF09531.5 CDJ69436.1 - 0.38 9.1 8.0 0.34 9.2 5.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDK5_activator PF03261.10 CDJ69436.1 - 0.45 9.7 13.0 0.67 9.2 9.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Activator_LAG-3 PF11498.3 CDJ69436.1 - 0.53 8.9 47.4 0.82 8.3 32.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2232 PF09991.4 CDJ69436.1 - 0.8 8.6 7.5 1.2 8.0 5.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) APG6 PF04111.7 CDJ69436.1 - 0.86 8.5 16.0 0.99 8.3 11.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Hid1 PF12722.2 CDJ69436.1 - 2.1 5.9 13.2 2.4 5.7 9.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CDJ69436.1 - 2.3 7.1 5.1 2.7 6.9 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CDJ69436.1 - 4.5 6.5 14.5 7.5 5.8 10.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Hamartin PF04388.7 CDJ69436.1 - 6.2 5.3 14.2 8.3 4.9 9.8 1.3 1 0 0 1 1 1 0 Hamartin protein Herpes_DNAp_acc PF04929.7 CDJ69436.1 - 7.3 5.4 12.6 10 4.9 8.8 1.5 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2215 PF10225.4 CDJ69436.1 - 7.5 5.9 7.0 9.8 5.5 4.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) eIF-3_zeta PF05091.7 CDJ69436.1 - 8.5 4.8 21.8 11 4.5 15.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF948 PF06103.6 CDJ69437.1 - 6.1 6.7 7.8 6.3 6.7 5.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.1 CDJ69442.1 - 0.00031 21.1 8.1 0.00033 21.0 5.6 1.1 1 0 0 1 1 1 1 AAA domain YfhO PF09586.5 CDJ69442.1 - 0.0026 15.8 11.9 0.0032 15.5 8.3 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO FimP PF09766.4 CDJ69442.1 - 0.015 14.3 18.9 0.02 13.9 13.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF3260 PF11658.3 CDJ69442.1 - 0.017 13.2 11.1 0.021 12.9 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) TRAP_alpha PF03896.11 CDJ69442.1 - 0.067 12.1 4.6 0.085 11.8 3.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SID-1_RNA_chan PF13965.1 CDJ69442.1 - 0.22 9.6 5.3 0.31 9.1 3.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.10 CDJ69442.1 - 0.29 9.7 9.4 0.45 9.1 6.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pap_E4 PF02711.9 CDJ69442.1 - 0.43 11.4 16.9 0.91 10.3 0.5 2.3 2 0 0 2 2 2 0 E4 protein Herpes_glycop PF01528.11 CDJ69442.1 - 0.52 8.9 4.2 0.74 8.4 2.9 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M FPN1 PF06963.7 CDJ69442.1 - 0.6 8.4 6.0 0.92 7.8 4.1 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3959 PF13105.1 CDJ69442.1 - 2.5 7.3 10.5 3.9 6.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) FAM176 PF14851.1 CDJ69442.1 - 3 7.5 7.4 2.3 7.8 3.2 2.0 2 0 0 2 2 2 0 FAM176 family DUF4175 PF13779.1 CDJ69442.1 - 3.6 5.1 40.4 4.8 4.7 28.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.5 CDJ69442.1 - 4.2 7.1 14.4 5.9 6.6 10.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4512 PF14975.1 CDJ69442.1 - 5.7 7.8 7.5 3.9 8.3 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) GCC2_GCC3 PF07699.8 CDJ69443.1 - 3.7e-12 45.6 38.3 3.5e-08 32.9 2.9 6.2 5 0 0 5 5 5 4 GCC2 and GCC3 Cwf_Cwc_15 PF04889.7 CDJ69443.1 - 2 8.0 20.9 0.04 13.6 3.0 3.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.1 CDJ69444.1 - 7.5 6.2 7.3 0.79 9.3 0.7 2.0 1 1 1 2 2 2 0 FAM176 family ubiquitin PF00240.18 CDJ69445.1 - 1.7e-68 225.9 5.7 6.1e-35 118.4 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CDJ69445.1 - 9.4e-41 137.3 5.2 3.3e-20 71.5 0.3 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDJ69445.1 - 2e-14 53.6 0.9 1.2e-05 25.4 0.1 3.3 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CDJ69445.1 - 6.1e-08 32.5 0.0 0.00087 19.0 0.0 2.1 2 0 0 2 2 2 2 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CDJ69445.1 - 4.8e-07 29.6 0.2 0.028 14.2 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDJ69445.1 - 1.2e-06 28.6 0.1 0.054 13.6 0.0 2.1 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 CDJ69445.1 - 1.7e-05 24.6 0.2 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 GLUT4 regulating protein TUG DUF2870 PF11069.3 CDJ69445.1 - 0.00014 21.8 0.0 0.48 10.5 0.0 2.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2870) USP7_C2 PF14533.1 CDJ69445.1 - 0.0026 17.2 0.2 1.7 8.0 0.0 2.1 1 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal FlgD_ig PF13860.1 CDJ69445.1 - 0.0036 16.9 0.2 3.5 7.4 0.0 2.3 2 0 0 2 2 2 2 FlgD Ig-like domain FERM_N PF09379.5 CDJ69445.1 - 0.03 14.3 1.0 12 6.0 0.1 3.1 3 1 0 3 3 3 0 FERM N-terminal domain CTDII PF01556.13 CDJ69445.1 - 0.03 14.2 3.3 1.1 9.1 0.2 2.2 1 1 1 2 2 2 0 DnaJ C terminal domain PI3K_rbd PF00794.13 CDJ69445.1 - 0.038 13.9 0.7 8.4 6.3 0.1 2.3 2 1 0 2 2 2 0 PI3-kinase family, ras-binding domain Plexin_cytopl PF08337.7 CDJ69445.1 - 0.17 10.1 2.4 2.8 6.1 0.1 2.8 3 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain TIM PF00121.13 CDJ69447.1 - 6.1e-51 172.8 0.2 4.6e-34 117.5 0.0 2.0 1 1 1 2 2 2 2 Triosephosphate isomerase POR PF01558.13 CDJ69447.1 - 0.096 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Not1 PF04054.10 CDJ69448.1 - 0.002 17.1 0.1 0.002 17.1 0.0 1.9 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 Rpp20 PF12328.3 CDJ69448.1 - 0.058 13.0 5.5 0.069 12.7 3.8 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P MPP6 PF10175.4 CDJ69448.1 - 0.066 13.5 0.7 0.12 12.7 0.5 1.5 1 1 0 1 1 1 0 M-phase phosphoprotein 6 ORC5_C PF14630.1 CDJ69448.1 - 0.16 11.3 4.9 0.17 11.3 3.4 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF4518 PF15008.1 CDJ69448.1 - 0.26 10.2 7.2 0.24 10.3 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) DUF3457 PF11939.3 CDJ69448.1 - 0.51 9.8 5.6 0.7 9.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) eIF-3_zeta PF05091.7 CDJ69448.1 - 0.56 8.7 9.6 0.57 8.7 6.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ctr PF04145.10 CDJ69448.1 - 0.59 10.1 2.4 0.56 10.2 1.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family FimP PF09766.4 CDJ69448.1 - 0.61 9.0 17.1 0.61 9.0 11.9 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF788 PF05620.6 CDJ69448.1 - 0.62 9.8 6.2 0.61 9.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) PKI PF02827.11 CDJ69448.1 - 0.75 9.9 3.1 0.92 9.6 2.1 1.2 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF2201_N PF13203.1 CDJ69448.1 - 0.95 8.5 10.0 1 8.4 6.9 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Scs3p PF10261.4 CDJ69448.1 - 1.3 7.9 3.2 1.4 7.9 2.2 1.0 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Spt20 PF12090.3 CDJ69448.1 - 1.7 7.9 11.9 1.7 7.9 8.2 1.1 1 0 0 1 1 1 0 Spt20 family FCP1_C PF09309.5 CDJ69448.1 - 1.7 7.8 10.0 1.7 7.9 7.0 1.1 1 0 0 1 1 1 0 FCP1, C-terminal PsiA PF06952.6 CDJ69448.1 - 1.7 7.6 13.3 1.8 7.5 9.2 1.0 1 0 0 1 1 1 0 PsiA protein Serinc PF03348.10 CDJ69448.1 - 1.7 7.2 6.9 1.6 7.3 4.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex14_N PF04695.8 CDJ69448.1 - 1.8 8.6 13.7 1.9 8.5 9.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAB3GAP2_N PF14655.1 CDJ69448.1 - 1.9 7.4 10.0 1.9 7.4 6.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF912 PF06024.7 CDJ69448.1 - 1.9 8.5 5.5 2.1 8.4 3.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ERF PF04404.7 CDJ69448.1 - 2 7.9 16.7 2 7.8 11.6 1.1 1 0 0 1 1 1 0 ERF superfamily ATAD4 PF15321.1 CDJ69448.1 - 2 9.4 6.1 2.1 9.4 4.2 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Peptidase_S49_N PF08496.5 CDJ69448.1 - 2.2 8.0 8.6 2.3 8.0 6.0 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LIM_bind PF01803.11 CDJ69448.1 - 2.6 7.0 10.4 2.6 7.0 7.2 1.0 1 0 0 1 1 1 0 LIM-domain binding protein AIF_C PF14721.1 CDJ69448.1 - 3 8.0 6.0 3 8.0 4.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med15 PF09606.5 CDJ69448.1 - 3.1 5.8 29.8 2.9 6.0 20.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kei1 PF08552.6 CDJ69448.1 - 3.3 7.3 6.6 3.1 7.4 4.5 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 EIIBC-GUT_N PF03612.9 CDJ69448.1 - 3.4 7.2 6.8 3.4 7.2 4.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus WASH-7_C PF14746.1 CDJ69448.1 - 3.7 7.1 7.6 4 7.0 5.3 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal G0-G1_switch_2 PF15103.1 CDJ69448.1 - 3.8 7.8 8.4 3.8 7.7 5.8 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Hid1 PF12722.2 CDJ69448.1 - 3.9 5.0 8.2 3.9 5.0 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4557 PF15101.1 CDJ69448.1 - 4.1 7.1 15.9 4.2 7.1 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Band_3_cyto PF07565.8 CDJ69448.1 - 4.5 6.6 8.2 4.5 6.6 5.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.9 CDJ69448.1 - 4.9 6.7 14.3 5.3 6.6 9.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) OATP PF03137.15 CDJ69448.1 - 7.1 4.5 6.4 7.6 4.4 4.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PAT1 PF09770.4 CDJ69448.1 - 9.8 4.2 22.1 9.5 4.3 15.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lipase_GDSL_2 PF13472.1 CDJ69449.1 - 0.019 15.0 1.6 0.024 14.7 1.1 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DDE_3 PF13358.1 CDJ69449.1 - 0.079 12.7 5.8 0.11 12.3 4.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease PGA_cap PF09587.5 CDJ69449.1 - 0.73 9.1 5.8 1 8.6 4.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Dynein_heavy PF03028.10 CDJ69450.1 - 3.5e-70 236.9 12.6 7.7e-36 123.4 0.0 6.7 7 0 0 7 7 7 5 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 CDJ69450.1 - 1.7e-44 152.0 10.9 5.2e-44 150.4 7.6 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CDJ69450.1 - 6.8e-21 74.1 0.5 6.4e-11 41.5 1.7 2.4 1 1 1 2 2 2 2 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDJ69450.1 - 4.3e-13 48.8 0.1 1.7e-07 30.4 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CDJ69450.1 - 2.1e-08 33.5 0.0 6.9e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 DUF1464 PF07318.7 CDJ69450.1 - 0.0012 17.7 0.4 0.0036 16.1 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1464) Autophagy_act_C PF03987.10 CDJ69451.1 - 8.8e-28 96.2 0.3 1.4e-27 95.6 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CDJ69451.1 - 1.4e-12 46.4 2.4 2.4e-12 45.6 1.7 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Mitofilin PF09731.4 CDJ69454.1 - 0.00059 18.6 7.7 0.00059 18.6 5.3 3.0 3 0 0 3 3 3 1 Mitochondrial inner membrane protein SAPS PF04499.10 CDJ69454.1 - 0.0037 15.9 14.6 0.42 9.1 0.0 2.4 2 1 0 2 2 2 2 SIT4 phosphatase-associated protein DGF-1_C PF11040.3 CDJ69454.1 - 9.7 6.1 10.9 2.2 8.2 1.3 3.5 2 2 1 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus BAF1_ABF1 PF04684.8 CDJ69456.1 - 0.0045 15.8 11.5 0.0045 15.8 7.9 6.4 5 1 3 8 8 8 1 BAF1 / ABF1 chromatin reorganising factor EF-hand_6 PF13405.1 CDJ69457.1 - 0.026 14.3 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF755 PF05501.6 CDJ69457.1 - 1.3 9.0 47.3 0.051 13.6 6.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF755) Pkinase PF00069.20 CDJ69458.1 - 3e-46 157.7 0.0 5.6e-42 143.6 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69458.1 - 7.9e-18 64.4 0.0 1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDJ69458.1 - 0.00055 18.9 0.0 0.00079 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDJ69458.1 - 0.0033 16.5 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 CDJ69458.1 - 0.074 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.18 CDJ69458.1 - 0.6 9.7 11.5 19 4.8 8.0 2.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mem_trans PF03547.13 CDJ69459.1 - 0.33 9.1 9.5 0.57 8.4 6.6 1.4 1 0 0 1 1 1 0 Membrane transport protein TFIIF_alpha PF05793.7 CDJ69459.1 - 1.5 7.1 26.0 0.02 13.3 13.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Membralin PF09746.4 CDJ69459.1 - 6 5.8 6.8 11 4.9 4.7 1.4 1 0 0 1 1 1 0 Tumour-associated protein Helicase_C PF00271.26 CDJ69460.1 - 1.6e-25 88.7 0.0 2.5e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1699 PF08004.6 CDJ69460.1 - 0.13 11.7 0.2 0.9 9.0 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1699) AMP-binding PF00501.23 CDJ69462.1 - 8.7e-69 231.8 0.0 1.5e-68 231.1 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme Peptidase_C26 PF07722.8 CDJ69463.1 - 2.4e-24 85.9 0.0 1.2e-18 67.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 GATase PF00117.23 CDJ69463.1 - 1.1e-12 47.8 0.1 1.1e-11 44.4 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CDJ69463.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MIF4G_like_2 PF09090.6 CDJ69464.1 - 1.7e-11 43.8 0.0 2.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 MIF4G like PsbQ PF05757.6 CDJ69465.1 - 0.019 14.3 1.3 0.033 13.6 0.9 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Med15 PF09606.5 CDJ69465.1 - 0.58 8.3 20.5 0.74 7.9 14.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ69465.1 - 1.3 8.8 13.7 1.8 8.3 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.14 CDJ69465.1 - 2.5 8.5 12.4 5.3 7.5 8.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1528 PF07515.6 CDJ69465.1 - 7 6.7 6.9 2.6 8.1 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1528) UPF0147 PF03685.8 CDJ69466.1 - 0.031 14.1 0.7 0.15 11.9 0.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) FlaC_arch PF05377.6 CDJ69466.1 - 3.7 7.5 10.2 0.15 11.9 0.5 3.6 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Adenylsucc_synt PF00709.16 CDJ69466.1 - 7.2 5.1 7.8 5.1 5.6 4.1 1.6 1 1 0 1 1 1 0 Adenylosuccinate synthetase Ribosomal_60s PF00428.14 CDJ69467.1 - 0.12 12.7 17.3 0.047 14.1 8.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein CytochromB561_N PF09786.4 CDJ69468.1 - 3 6.2 21.4 3.3 6.0 14.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Dehydrin PF00257.14 CDJ69469.1 - 0.016 15.5 0.1 0.016 15.5 0.1 8.1 7 1 0 7 7 7 0 Dehydrin NLBH PF05211.7 CDJ69469.1 - 0.23 10.6 2.7 1.7 7.8 0.1 2.4 2 0 0 2 2 2 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) SpoV PF08183.6 CDJ69471.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.2 3 0 0 3 3 3 0 Stage V sporulation protein family DUF1469 PF07332.6 CDJ69471.1 - 0.22 11.2 4.5 2.2 8.0 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF4395 PF14340.1 CDJ69471.1 - 1.9 8.5 8.8 2.9 7.9 6.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) IspD PF01128.14 CDJ69472.1 - 4.1e-14 52.6 10.9 3.7e-12 46.2 3.9 3.4 3 0 0 3 3 3 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SPX PF03105.14 CDJ69472.1 - 0.00027 20.8 9.1 0.00028 20.7 0.1 2.7 1 1 0 2 2 2 1 SPX domain PRA1 PF03208.14 CDJ69472.1 - 0.24 10.7 0.9 0.66 9.2 0.0 2.2 2 0 0 2 2 2 0 PRA1 family protein PAT1 PF09770.4 CDJ69472.1 - 5 5.2 85.6 0.0085 14.4 37.5 3.2 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDJ69473.1 - 1.2e-05 24.8 6.8 1.2e-05 24.8 4.7 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2217 PF10265.4 CDJ69473.1 - 3.6 6.2 5.7 5.3 5.6 3.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) EF-hand_1 PF00036.27 CDJ69474.1 - 2.4e-40 132.7 10.7 1.6e-09 36.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDJ69474.1 - 2.4e-35 120.4 5.7 1e-18 67.1 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDJ69474.1 - 8.4e-34 114.9 10.4 3.5e-17 61.7 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CDJ69474.1 - 2.1e-28 95.5 6.9 1.2e-09 37.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CDJ69474.1 - 1.2e-26 90.7 7.7 8.3e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CDJ69474.1 - 5.4e-14 51.8 0.1 3.5e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CDJ69474.1 - 1.9e-09 37.2 0.4 0.00029 20.5 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CDJ69474.1 - 4.8e-08 33.0 0.0 0.0054 16.7 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CDJ69474.1 - 2.1e-05 24.0 0.0 0.21 11.2 0.0 2.6 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CDJ69474.1 - 0.00024 20.9 0.4 0.005 16.7 0.0 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 CDJ69474.1 - 0.00056 19.5 0.1 0.036 13.6 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein TerB PF05099.8 CDJ69474.1 - 0.00094 18.9 0.1 0.21 11.3 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB DUF1103 PF06513.6 CDJ69474.1 - 0.0046 16.3 1.2 0.0055 16.1 0.8 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) RNA_pol_Rpb4 PF03874.11 CDJ69474.1 - 0.0079 16.1 0.6 2 8.4 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 YqeY PF09424.5 CDJ69474.1 - 0.013 15.3 0.2 0.14 11.9 0.0 2.0 1 1 1 2 2 2 0 Yqey-like protein DUF853 PF05872.7 CDJ69474.1 - 0.022 13.1 0.2 0.59 8.4 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) LNS2 PF08235.8 CDJ69474.1 - 0.072 12.6 0.0 0.46 10.0 0.0 1.9 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) VCBS PF13517.1 CDJ69474.1 - 7.8 6.9 6.8 24 5.3 0.4 2.6 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_S10 PF00338.17 CDJ69475.1 - 1.4e-29 101.7 0.1 1.6e-29 101.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1922 PF09082.5 CDJ69475.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Ribosomal_L35Ae PF01247.13 CDJ69476.1 - 9.7e-43 143.8 0.9 1.2e-42 143.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CDJ69476.1 - 0.072 13.0 0.1 7.8 6.4 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain OMPdecase PF00215.19 CDJ69477.1 - 1.5e-25 89.9 0.0 1.4e-24 86.8 0.0 1.9 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 CDJ69477.1 - 0.016 14.3 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG AP2 PF00847.15 CDJ69478.1 - 2.2e-12 46.9 10.6 2.9e-07 30.5 1.9 9.0 10 0 0 10 10 10 3 AP2 domain ACDC PF14733.1 CDJ69478.1 - 1.4e-07 31.5 0.0 4.7e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 AP2-coincident C-terminal RLL PF10036.4 CDJ69479.1 - 4.3e-19 68.9 9.6 1.1e-13 51.2 0.2 3.0 2 1 0 2 2 2 2 Putative carnitine deficiency-associated protein TSA PF03249.8 CDJ69479.1 - 2 6.8 6.0 4 5.8 4.2 1.5 1 0 0 1 1 1 0 Type specific antigen DUF4557 PF15101.1 CDJ69479.1 - 2 8.2 5.6 0.19 11.5 0.9 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF1499 PF07386.6 CDJ69479.1 - 4.9 7.3 5.5 4.7 7.4 1.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1499) PGM_PMM_II PF02879.11 CDJ69480.1 - 1.3e-13 51.1 0.2 4.3e-07 30.2 0.0 3.3 2 1 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 CDJ69480.1 - 1.9e-07 30.6 0.1 4e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SR-25 PF10500.4 CDJ69480.1 - 4.4 6.7 12.9 0.04 13.3 3.5 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BBS2_C PF14782.1 CDJ69480.1 - 8.6 4.7 5.9 12 4.2 4.1 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF1675 PF07897.6 CDJ69481.1 - 0.85 9.4 16.7 1.1 9.0 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RR_TM4-6 PF06459.7 CDJ69481.1 - 1.8 8.3 10.9 2.4 7.9 7.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CDJ69481.1 - 2.1 6.4 40.6 2.6 6.1 28.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FLO_LFY PF01698.11 CDJ69481.1 - 2.7 6.7 11.3 3.5 6.3 7.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 CDJ69481.1 - 3.3 6.1 10.5 4.4 5.7 7.3 1.1 1 0 0 1 1 1 0 Raftlin Tom37_C PF11801.3 CDJ69481.1 - 5.3 6.8 9.9 9.7 6.0 6.9 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Parvo_coat PF00740.13 CDJ69481.1 - 6.6 5.5 12.9 8 5.2 9.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CDC45 PF02724.9 CDJ69481.1 - 6.7 4.6 12.2 8.1 4.3 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.5 CDJ69482.1 - 0.00015 20.1 100.1 0.0035 15.6 34.0 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal SeqA PF03925.8 CDJ69482.1 - 0.097 12.3 20.4 0.45 10.1 2.4 2.6 2 0 0 2 2 2 0 SeqA protein zf-DHHC PF01529.15 CDJ69482.1 - 0.34 10.2 1.4 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase FHIPEP PF00771.15 CDJ69482.1 - 2.9 6.1 19.5 0.23 9.7 3.6 2.3 2 0 0 2 2 2 0 FHIPEP family Dala_Dala_lig_N PF01820.16 CDJ69482.1 - 5.2 7.4 10.6 1.6 9.0 0.7 2.9 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus IncA PF04156.9 CDJ69483.1 - 0.0021 17.7 1.7 0.0026 17.3 1.2 1.1 1 0 0 1 1 1 1 IncA protein DUF1470 PF07336.6 CDJ69483.1 - 8.1 6.7 13.1 42 4.4 9.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1470) CDC45 PF02724.9 CDJ69484.1 - 0.036 12.1 17.2 0.038 12.0 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.1 CDJ69484.1 - 0.13 11.5 16.7 0.14 11.3 11.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nop53 PF07767.6 CDJ69484.1 - 0.15 10.9 23.7 0.17 10.8 16.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3337 PF11816.3 CDJ69484.1 - 0.25 10.6 11.6 0.29 10.5 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) GAGA_bind PF06217.7 CDJ69484.1 - 0.3 11.0 17.6 0.35 10.7 12.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 CDJ69484.1 - 0.35 10.2 21.2 0.44 9.8 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CKAP2_C PF15297.1 CDJ69484.1 - 0.35 9.6 19.0 0.42 9.3 13.2 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus PAT1 PF09770.4 CDJ69484.1 - 0.36 8.9 49.8 0.41 8.8 34.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.9 CDJ69484.1 - 0.37 10.1 24.4 0.46 9.8 16.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Herpes_UL17 PF04559.7 CDJ69484.1 - 0.4 9.2 9.5 0.46 9.0 6.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein Caldesmon PF02029.10 CDJ69484.1 - 0.44 8.9 17.1 0.5 8.7 11.9 1.0 1 0 0 1 1 1 0 Caldesmon FAM60A PF15396.1 CDJ69484.1 - 0.63 9.7 17.8 0.7 9.6 12.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.2 CDJ69484.1 - 0.7 7.5 19.8 0.76 7.3 13.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDK5_activator PF03261.10 CDJ69484.1 - 0.71 9.1 19.4 0.79 9.0 13.4 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Tim54 PF11711.3 CDJ69484.1 - 0.74 8.3 13.5 0.9 8.0 9.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 CDJ69484.1 - 0.92 8.0 17.5 0.99 7.9 12.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4569 PF15133.1 CDJ69484.1 - 0.95 8.7 20.7 1.1 8.5 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) FAM91_C PF14648.1 CDJ69484.1 - 0.96 8.2 10.7 1.1 8.0 7.4 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Mcm10 PF09332.6 CDJ69484.1 - 0.98 8.7 17.9 1.1 8.5 12.4 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Endostatin PF06482.6 CDJ69484.1 - 1.1 8.5 15.3 1.3 8.3 10.6 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Dsh_C PF12316.3 CDJ69484.1 - 1.1 9.3 11.6 1.2 9.2 8.1 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SRP-alpha_N PF04086.8 CDJ69484.1 - 1.2 8.4 19.9 1.4 8.2 13.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PXA PF02194.10 CDJ69484.1 - 1.2 8.6 12.4 1.5 8.3 8.6 1.1 1 0 0 1 1 1 0 PXA domain RNA_pol_Rpb1_5 PF04998.12 CDJ69484.1 - 1.3 8.1 9.9 1.5 8.0 6.9 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AUX_IAA PF02309.11 CDJ69484.1 - 1.3 8.6 17.7 1.7 8.3 12.3 1.2 1 0 0 1 1 1 0 AUX/IAA family Spore_coat_CotO PF14153.1 CDJ69484.1 - 1.6 8.1 29.6 2.1 7.7 20.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TFIIA PF03153.8 CDJ69484.1 - 1.6 8.5 37.3 1.8 8.3 25.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.1 CDJ69484.1 - 1.7 7.0 19.8 1.9 6.8 13.8 1.0 1 0 0 1 1 1 0 Raftlin DUF2052 PF09747.4 CDJ69484.1 - 1.9 8.4 26.0 2.3 8.1 18.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1387 PF07139.6 CDJ69484.1 - 1.9 8.0 13.3 2.1 7.9 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF3595 PF12166.3 CDJ69484.1 - 1.9 7.2 13.0 2 7.1 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) SMN PF06003.7 CDJ69484.1 - 1.9 7.5 8.2 2.3 7.2 5.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Glyco_transf_15 PF01793.11 CDJ69484.1 - 1.9 7.3 16.2 2.4 7.0 11.2 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase SPX PF03105.14 CDJ69484.1 - 2 8.1 19.3 2.2 7.9 13.4 1.1 1 0 0 1 1 1 0 SPX domain Zip PF02535.17 CDJ69484.1 - 2.1 7.3 16.2 2.4 7.0 11.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cellulose_synt PF03552.9 CDJ69484.1 - 2.1 6.5 8.8 2.3 6.3 6.1 1.0 1 0 0 1 1 1 0 Cellulose synthase Drc1-Sld2 PF11719.3 CDJ69484.1 - 2.2 7.2 21.9 2.8 6.9 15.2 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Pal1 PF08316.6 CDJ69484.1 - 2.3 8.6 11.0 3.4 8.1 7.6 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein Amidase PF01425.16 CDJ69484.1 - 2.4 6.9 5.4 2.6 6.7 3.8 1.0 1 0 0 1 1 1 0 Amidase YjgP_YjgQ PF03739.9 CDJ69484.1 - 2.4 6.8 5.7 2.7 6.6 3.9 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Peptidase_S64 PF08192.6 CDJ69484.1 - 2.5 6.3 13.7 2.7 6.2 9.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Dynamin_N PF00350.18 CDJ69484.1 - 2.6 7.8 9.5 3.8 7.3 6.6 1.3 1 0 0 1 1 1 0 Dynamin family SAGA-Tad1 PF12767.2 CDJ69484.1 - 2.6 7.6 23.6 3.2 7.3 16.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF342 PF03961.8 CDJ69484.1 - 2.7 6.3 10.8 2.8 6.2 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3449 PF11931.3 CDJ69484.1 - 2.9 7.3 21.6 3.7 7.0 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) F-protein PF00469.15 CDJ69484.1 - 3 7.1 20.2 3.6 6.8 14.0 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF2126 PF09899.4 CDJ69484.1 - 3.2 5.6 15.3 3.6 5.5 10.6 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RR_TM4-6 PF06459.7 CDJ69484.1 - 3.2 7.5 21.1 4 7.2 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.3 CDJ69484.1 - 3.5 7.2 21.1 4.4 6.9 14.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Spc7_N PF15402.1 CDJ69484.1 - 3.6 5.4 22.6 4.2 5.2 15.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 VID27 PF08553.5 CDJ69484.1 - 3.8 5.6 14.0 4.1 5.4 9.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Macoilin PF09726.4 CDJ69484.1 - 3.9 5.6 18.4 4.5 5.4 12.7 1.1 1 0 0 1 1 1 0 Transmembrane protein PIG-S PF10510.4 CDJ69484.1 - 4 6.0 18.7 4.3 5.8 13.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Peptidase_S15 PF02129.13 CDJ69484.1 - 4 6.7 15.3 5 6.4 10.6 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SprA-related PF12118.3 CDJ69484.1 - 4.4 6.5 51.7 5.5 6.2 35.9 1.0 1 0 0 1 1 1 0 SprA-related family DUF4220 PF13968.1 CDJ69484.1 - 5.7 5.9 11.6 6.5 5.7 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) AvrE PF11725.3 CDJ69484.1 - 5.7 3.8 22.8 6.2 3.6 15.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor cwf18 PF08315.7 CDJ69484.1 - 6.3 7.2 23.9 8.5 6.8 16.6 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF1675 PF07897.6 CDJ69484.1 - 6.6 6.5 14.9 7.8 6.2 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Radical_SAM_N PF08497.5 CDJ69484.1 - 7.1 5.4 16.2 8.4 5.2 11.2 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal HlyD_2 PF12700.2 CDJ69484.1 - 7.8 5.5 17.6 8.8 5.3 12.2 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Asp-B-Hydro_N PF05279.6 CDJ69484.1 - 8.3 6.1 17.1 10 5.8 11.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF853 PF05872.7 CDJ69484.1 - 9.1 4.5 16.2 13 4.0 11.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Peptidase_U57 PF05582.7 CDJ69484.1 - 9.1 5.1 17.1 12 4.7 11.8 1.2 1 0 0 1 1 1 0 YabG peptidase U57 vMSA PF00695.14 CDJ69484.1 - 9.5 5.3 14.7 12 4.9 10.2 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus RBP_receptor PF14752.1 CDJ69484.1 - 9.5 4.3 7.1 12 4.1 4.9 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor DDRGK PF09756.4 CDJ69484.1 - 9.6 5.5 31.6 14 4.9 21.9 1.3 1 0 0 1 1 1 0 DDRGK domain Totivirus_coat PF05518.6 CDJ69484.1 - 10 3.8 13.9 11 3.6 9.6 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF755 PF05501.6 CDJ69485.1 - 0.00055 19.9 4.7 0.00055 19.9 3.3 6.5 5 1 1 6 6 6 1 Domain of unknown function (DUF755) PAT1 PF09770.4 CDJ69485.1 - 0.0012 17.2 70.2 0.0012 17.2 48.7 2.2 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDJ69485.1 - 6 6.1 65.9 0.2 10.9 13.5 3.3 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 CDJ69485.1 - 8.5 4.3 7.5 12 3.8 5.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Met_10 PF02475.11 CDJ69486.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DUF3523 PF12037.3 CDJ69487.1 - 1.8e-58 197.7 22.8 1.8e-58 197.7 15.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) YqzE PF14038.1 CDJ69487.1 - 1.8 8.3 0.0 1.8 8.3 0.0 3.3 3 1 0 3 3 3 0 YqzE-like protein SDH_beta PF03315.10 CDJ69487.1 - 8.1 6.4 6.4 1.4 8.9 1.0 2.2 1 1 1 2 2 2 0 Serine dehydratase beta chain SF-assemblin PF06705.6 CDJ69489.1 - 0.0019 17.4 25.6 0.0019 17.4 17.8 4.5 3 1 1 4 4 4 2 SF-assemblin/beta giardin DUF755 PF05501.6 CDJ69489.1 - 0.015 15.3 16.1 0.015 15.3 11.2 8.0 7 1 0 7 7 7 0 Domain of unknown function (DUF755) Nipped-B_C PF12830.2 CDJ69489.1 - 0.15 11.6 27.2 0.042 13.4 1.0 4.0 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus Coq4 PF05019.8 CDJ69490.1 - 1.8e-49 167.6 0.1 6e-47 159.3 0.0 2.2 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TraV PF09676.5 CDJ69490.1 - 0.45 11.2 5.8 0.21 12.2 2.0 1.9 2 1 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) RNA_pol_Rpb1_5 PF04998.12 CDJ69492.1 - 1.1e-29 103.5 0.1 3.8e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 CDJ69492.1 - 2.8e-16 59.1 0.1 1.4e-15 56.9 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Ribosomal_L37 PF08561.5 CDJ69492.1 - 0.29 10.7 4.1 0.58 9.7 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 RNA_pol_Rpb1_5 PF04998.12 CDJ69493.1 - 2.2e-48 164.9 0.0 2.2e-27 96.0 0.6 2.6 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 5 Med15 PF09606.5 CDJ69493.1 - 0.0037 15.5 62.6 0.037 12.2 27.7 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ69493.1 - 9.2 4.3 59.5 2.3 6.3 31.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDJ69495.1 - 0.073 11.2 77.7 0.088 10.9 53.8 1.0 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.4 CDJ69495.1 - 8.2 4.5 126.0 9.8 4.2 87.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EMP24_GP25L PF01105.19 CDJ69496.1 - 3.8e-29 101.7 0.0 6e-29 101.0 0.0 1.3 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD DUF1944 PF09175.5 CDJ69496.1 - 0.067 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) DUF3753 PF12575.3 CDJ69498.1 - 0.18 11.6 2.4 0.2 11.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF4245 PF14030.1 CDJ69499.1 - 0.0007 19.3 0.2 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) RRM_6 PF14259.1 CDJ69500.1 - 0.2 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ycf1 PF05758.7 CDJ69500.1 - 1.6 6.3 3.4 2.8 5.5 2.4 1.2 1 0 0 1 1 1 0 Ycf1 Guanylate_kin PF00625.16 CDJ69501.1 - 4.2e-51 172.9 0.0 4.9e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 CDJ69501.1 - 5.5e-06 26.4 0.2 1.1e-05 25.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CDJ69501.1 - 2.1e-05 24.8 0.6 0.0003 21.1 0.4 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDJ69501.1 - 0.00041 19.5 0.0 0.00058 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CDJ69501.1 - 0.00041 21.1 0.1 0.001 19.8 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 CDJ69501.1 - 0.00087 19.1 0.6 0.014 15.2 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDJ69501.1 - 0.0062 16.6 0.0 0.026 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CDJ69501.1 - 0.033 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 CDJ69501.1 - 0.094 12.1 0.1 0.63 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CDJ69501.1 - 0.099 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 CDJ69501.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.1 CDJ69501.1 - 0.16 11.5 0.2 0.36 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNase_H PF00075.19 CDJ69502.1 - 2.1e-21 76.6 0.0 3.5e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 RNase H SpoIIE PF07228.7 CDJ69503.1 - 0.0066 16.1 0.0 0.033 13.8 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PBP PF01161.15 CDJ69504.1 - 1.8e-06 27.8 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_65m PF03632.10 CDJ69504.1 - 0.0058 15.3 0.1 0.0082 14.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain HEAT PF02985.17 CDJ69505.1 - 4.2e-05 23.2 1.9 0.18 11.9 0.0 5.7 4 0 0 4 4 4 1 HEAT repeat Ecm29 PF13001.2 CDJ69506.1 - 0.013 14.0 0.1 0.016 13.6 0.1 1.1 1 0 0 1 1 1 0 Proteasome stabiliser Zn_peptidase_2 PF04298.7 CDJ69506.1 - 0.053 12.8 0.1 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Chorion_2 PF03964.10 CDJ69506.1 - 0.22 12.0 4.6 0.3 11.6 3.2 1.2 1 0 0 1 1 1 0 Chorion family 2 DTW PF03942.10 CDJ69507.1 - 5.2e-11 42.1 0.3 8.6e-08 31.6 0.1 2.6 2 1 0 2 2 2 2 DTW domain TAF4 PF05236.9 CDJ69507.1 - 1.7 7.8 6.2 0.52 9.5 0.6 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family DUF1700 PF08006.6 CDJ69508.1 - 0.019 14.2 0.8 0.031 13.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Abhydrolase_5 PF12695.2 CDJ69508.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Helicase_C PF00271.26 CDJ69508.1 - 0.05 13.4 0.0 1.2 9.0 0.0 2.8 4 0 0 4 4 4 0 Helicase conserved C-terminal domain UPF0258 PF06789.7 CDJ69508.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Herpes_US9 PF06072.6 CDJ69508.1 - 0.66 9.8 4.8 0.18 11.6 0.5 2.2 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 TraL PF07178.6 CDJ69508.1 - 1.4 8.9 4.5 2.6 8.0 3.1 1.4 1 0 0 1 1 1 0 TraL protein PCI PF01399.22 CDJ69509.1 - 1.8e-20 73.2 1.2 5.3e-20 71.6 0.1 2.3 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 CDJ69509.1 - 3e-20 72.3 3.3 7.8e-20 71.0 2.3 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal CCDC32 PF14989.1 CDJ69509.1 - 0.054 13.3 3.9 3 7.6 0.6 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing 32 POR_N PF01855.14 CDJ69509.1 - 0.061 12.8 1.4 0.12 11.8 1.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Secretin_N_2 PF07655.8 CDJ69509.1 - 0.19 12.1 1.2 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain POX PF07526.6 CDJ69511.1 - 4.9 7.3 10.8 0.15 12.2 1.9 2.3 2 1 0 2 2 2 0 Associated with HOX PP2C_2 PF13672.1 CDJ69512.1 - 0.013 14.8 2.5 0.018 14.4 1.7 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Sox_N PF12444.3 CDJ69512.1 - 0.82 10.8 3.6 1.6 9.8 2.5 1.5 1 0 0 1 1 1 0 Sox developmental protein N terminal EMP70 PF02990.11 CDJ69514.1 - 2.3e-19 69.2 0.0 2.4e-12 46.0 0.0 3.3 2 1 1 3 3 3 3 Endomembrane protein 70 SR-25 PF10500.4 CDJ69514.1 - 1.7e-05 24.3 4.1 1.7e-05 24.3 2.8 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SOBP PF15279.1 CDJ69514.1 - 0.00027 21.4 10.2 0.00038 20.9 7.0 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein FimP PF09766.4 CDJ69514.1 - 0.0029 16.7 6.0 0.0029 16.7 4.1 1.7 2 0 0 2 2 2 1 Fms-interacting protein YjgP_YjgQ PF03739.9 CDJ69514.1 - 0.0041 15.9 0.1 0.012 14.3 0.1 1.8 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Med15 PF09606.5 CDJ69514.1 - 0.0043 15.3 35.9 0.0074 14.5 24.9 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDJ69514.1 - 0.0048 15.8 12.4 0.0048 15.8 8.6 4.9 5 0 0 5 5 3 2 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.14 CDJ69514.1 - 0.08 13.3 0.6 0.08 13.3 0.4 5.5 5 1 0 5 5 4 0 60s Acidic ribosomal protein Ribosomal_L6e PF01159.14 CDJ69514.1 - 1.6 9.0 8.1 0.35 11.1 3.4 1.5 2 0 0 2 2 1 0 Ribosomal protein L6e PAT1 PF09770.4 CDJ69514.1 - 2.6 6.1 36.5 3.8 5.6 25.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BRF1 PF07741.8 CDJ69514.1 - 4.1 7.6 10.7 1.8 8.8 1.1 2.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain MRP-L47 PF06984.8 CDJ69515.1 - 4.8e-24 84.0 0.4 4.8e-24 84.0 0.3 2.0 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) WHG PF13305.1 CDJ69515.1 - 0.16 12.5 4.0 0.59 10.7 0.2 2.4 2 0 0 2 2 2 0 WHG domain Noc2 PF03715.8 CDJ69517.1 - 2.9e-16 59.1 0.0 2.9e-16 59.1 0.0 2.6 3 0 0 3 3 3 1 Noc2p family KH_1 PF00013.24 CDJ69518.1 - 1.7e-17 62.8 0.2 4.2e-09 35.9 0.1 2.9 2 1 0 2 2 2 2 KH domain KH_3 PF13014.1 CDJ69518.1 - 2.5e-15 55.7 0.5 3.8e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CDJ69518.1 - 2.9e-05 23.5 0.3 0.02 14.4 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 CDJ69518.1 - 0.00023 20.9 0.0 0.71 9.7 0.0 2.5 2 0 0 2 2 2 2 NusA-like KH domain Voltage_CLC PF00654.15 CDJ69519.1 - 3.2e-67 227.0 35.8 3.9e-52 177.4 14.7 2.8 3 0 0 3 3 3 2 Voltage gated chloride channel DUF3464 PF11947.3 CDJ69519.1 - 0.069 12.6 0.1 0.26 10.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) Retrotrans_gag PF03732.12 CDJ69522.1 - 0.0087 16.1 0.0 0.042 13.9 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DNA_ligase_A_C PF04679.10 CDJ69523.1 - 0.11 12.9 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region FAM104 PF15434.1 CDJ69524.1 - 0.0055 16.8 9.0 0.0087 16.2 6.3 1.3 1 0 0 1 1 1 1 Family 104 DUF3338 PF11819.3 CDJ69524.1 - 0.009 15.4 0.7 0.009 15.4 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3338) DUF2217 PF10265.4 CDJ69524.1 - 0.01 14.6 4.0 0.012 14.4 2.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DDHD PF02862.12 CDJ69524.1 - 0.068 12.9 3.8 0.084 12.6 2.6 1.1 1 0 0 1 1 1 0 DDHD domain RasGEF_N PF00618.15 CDJ69524.1 - 0.1 12.7 0.6 0.17 11.9 0.4 1.3 1 0 0 1 1 1 0 RasGEF N-terminal motif Cwf_Cwc_15 PF04889.7 CDJ69524.1 - 0.16 11.6 5.8 0.21 11.2 4.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sulfotransfer_2 PF03567.9 CDJ69524.1 - 0.17 11.5 1.1 0.21 11.2 0.8 1.1 1 0 0 1 1 1 0 Sulfotransferase family Striatin PF08232.7 CDJ69524.1 - 0.21 11.8 11.2 0.38 11.0 7.7 1.3 1 0 0 1 1 1 0 Striatin family Seryl_tRNA_N PF02403.17 CDJ69524.1 - 0.24 11.4 8.1 0.42 10.6 5.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Corona_nucleoca PF00937.13 CDJ69524.1 - 0.26 10.1 7.6 0.31 9.9 5.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Vps39_1 PF10366.4 CDJ69524.1 - 0.29 11.1 4.9 0.71 9.9 3.4 1.6 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 AATF-Che1 PF13339.1 CDJ69524.1 - 0.32 11.1 9.6 0.51 10.4 6.7 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF1117 PF06547.7 CDJ69524.1 - 0.37 10.8 5.1 0.81 9.8 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) APG6 PF04111.7 CDJ69524.1 - 0.41 9.6 8.8 0.6 9.0 6.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FAM60A PF15396.1 CDJ69524.1 - 0.57 9.9 5.5 0.79 9.4 3.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4570 PF15134.1 CDJ69524.1 - 0.58 10.0 6.9 1 9.2 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF3446 PF11928.3 CDJ69524.1 - 0.75 10.0 16.8 3.5 7.8 10.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF2146 PF10220.4 CDJ69524.1 - 0.88 7.4 7.2 1.2 7.0 5.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) BNIP3 PF06553.7 CDJ69524.1 - 0.94 8.8 12.3 1.3 8.3 8.5 1.2 1 0 0 1 1 1 0 BNIP3 DUF342 PF03961.8 CDJ69524.1 - 1.1 7.6 5.8 1.4 7.2 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_S64 PF08192.6 CDJ69524.1 - 1.9 6.6 7.6 2.4 6.3 5.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 CAF-1_p150 PF11600.3 CDJ69524.1 - 3 7.1 13.3 4.7 6.5 9.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HisKA_3 PF07730.8 CDJ69524.1 - 4.6 7.6 13.4 2 8.8 0.8 3.4 3 0 0 3 3 3 0 Histidine kinase DUF3138 PF11336.3 CDJ69524.1 - 5.8 4.9 18.3 0.0084 14.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) RAP1 PF07218.6 CDJ69524.1 - 7.3 4.5 10.3 9.3 4.2 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UIM PF02809.15 CDJ69524.1 - 7.9 6.3 10.1 1.2 8.8 0.8 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif SR-25 PF10500.4 CDJ69526.1 - 3.8e-05 23.2 27.3 0.00067 19.1 7.8 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Mito_carr PF00153.22 CDJ69526.1 - 0.0017 17.9 0.9 0.0017 17.9 0.6 5.3 4 2 2 6 6 6 1 Mitochondrial carrier protein DUF4614 PF15391.1 CDJ69526.1 - 0.53 10.0 14.5 0.19 11.4 5.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) TraG-D_C PF12696.2 CDJ69526.1 - 2 8.2 6.4 0.43 10.4 0.7 2.1 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Pap_E4 PF02711.9 CDJ69526.1 - 2.8 8.7 4.4 12 6.8 0.7 2.3 2 0 0 2 2 2 0 E4 protein CAF-1_p150 PF11600.3 CDJ69526.1 - 4.1 6.7 18.9 1.2 8.4 5.2 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAM117 PF15388.1 CDJ69526.1 - 5.9 6.0 15.0 5.4 6.1 5.2 2.2 2 0 0 2 2 2 0 Protein Family FAM117 DUF755 PF05501.6 CDJ69526.1 - 6.1 6.9 38.1 1.1 9.3 6.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Tmemb_cc2 PF10267.4 CDJ69527.1 - 1.4 7.4 33.1 0.0076 14.8 6.7 2.1 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF1382 PF07131.6 CDJ69528.1 - 0.055 13.5 0.0 0.063 13.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1382) HTH_WhiA PF02650.9 CDJ69528.1 - 0.076 13.4 0.7 0.09 13.1 0.5 1.0 1 0 0 1 1 1 0 WhiA C-terminal HTH domain LcrG PF07216.7 CDJ69528.1 - 0.1 12.6 2.2 0.12 12.3 1.5 1.1 1 0 0 1 1 1 0 LcrG protein DUF4355 PF14265.1 CDJ69528.1 - 0.27 11.1 3.5 0.32 10.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) SR-25 PF10500.4 CDJ69529.1 - 0.0014 18.1 20.5 0.0014 18.1 14.2 3.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein TAF4 PF05236.9 CDJ69529.1 - 0.58 9.3 22.1 0.043 13.0 8.5 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family TSA PF03249.8 CDJ69529.1 - 8.8 4.7 11.0 12 4.3 7.6 1.1 1 0 0 1 1 1 0 Type specific antigen PGA2 PF07543.7 CDJ69529.1 - 9.3 6.0 7.3 0.69 9.6 1.0 1.9 1 1 1 2 2 2 0 Protein trafficking PGA2 Ycf1 PF05758.7 CDJ69531.1 - 8 4.0 21.4 2.8 5.5 9.0 2.3 2 0 0 2 2 2 0 Ycf1 TruB_N PF01509.13 CDJ69532.1 - 6.1e-25 88.1 0.0 1.2e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DUF605 PF04652.11 CDJ69532.1 - 0.034 13.5 22.5 0.011 15.1 5.3 2.1 2 0 0 2 2 2 0 Vta1 like TSA PF03249.8 CDJ69532.1 - 0.35 9.3 6.3 0.49 8.8 4.4 1.1 1 0 0 1 1 1 0 Type specific antigen EF-hand_7 PF13499.1 CDJ69533.1 - 1.1e-19 70.2 7.9 3.9e-06 26.9 0.2 5.4 4 1 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 CDJ69533.1 - 3.4e-18 63.4 9.6 0.00025 20.1 0.1 7.7 8 0 0 8 8 8 5 EF hand EF-hand_8 PF13833.1 CDJ69533.1 - 2.3e-13 49.4 13.9 5.7e-08 32.2 0.2 5.8 7 1 0 7 7 7 3 EF-hand domain pair EF-hand_6 PF13405.1 CDJ69533.1 - 3.9e-12 44.9 11.3 0.12 12.2 0.1 7.2 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 CDJ69533.1 - 1.7e-07 30.2 8.3 0.00058 19.0 0.0 5.2 6 0 0 6 6 6 3 EF hand Metallophos PF00149.23 CDJ69533.1 - 0.00031 20.1 0.1 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ycf1 PF05758.7 CDJ69534.1 - 7.9e-07 27.2 3.5 8e-07 27.2 2.4 1.1 1 0 0 1 1 1 1 Ycf1 Spore_coat_CotO PF14153.1 CDJ69534.1 - 6.1e-05 22.5 15.3 6.1e-05 22.5 10.6 1.9 2 0 0 2 2 2 1 Spore coat protein CotO Zip PF02535.17 CDJ69534.1 - 6.6e-05 22.0 8.2 0.00023 20.2 3.9 2.2 2 0 0 2 2 2 1 ZIP Zinc transporter Otopetrin PF03189.8 CDJ69534.1 - 0.012 14.6 4.1 0.016 14.2 2.9 1.3 1 0 0 1 1 1 0 Otopetrin LicD PF04991.8 CDJ69534.1 - 0.064 13.3 2.9 0.1 12.7 2.0 1.2 1 0 0 1 1 1 0 LicD family K_trans PF02705.11 CDJ69534.1 - 0.077 11.3 0.7 0.12 10.7 0.5 1.2 1 0 0 1 1 1 0 K+ potassium transporter LMBR1 PF04791.11 CDJ69534.1 - 0.3 9.6 4.6 0.42 9.1 3.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Dicty_REP PF05086.7 CDJ69534.1 - 0.76 7.4 11.1 1.1 6.9 7.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein eIF-3_zeta PF05091.7 CDJ69534.1 - 0.83 8.1 24.3 1.2 7.6 16.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.8 CDJ69534.1 - 1.3 8.4 27.3 0.016 14.7 12.2 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.1 CDJ69534.1 - 1.4 7.0 8.1 2.4 6.2 5.6 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Nucleoside_tran PF01733.13 CDJ69534.1 - 2.3 7.3 4.6 4 6.5 3.2 1.3 1 0 0 1 1 1 0 Nucleoside transporter Tim54 PF11711.3 CDJ69534.1 - 3.9 5.9 18.1 1.2 7.6 10.0 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 BTV_NS2 PF04514.7 CDJ69534.1 - 6.9 5.4 14.9 12 4.6 10.4 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DDHD PF02862.12 CDJ69534.1 - 8.5 6.1 29.3 1.2 8.8 0.2 2.9 3 0 0 3 3 3 0 DDHD domain FHIPEP PF00771.15 CDJ69534.1 - 8.9 4.5 13.6 0.11 10.8 3.7 1.9 2 0 0 2 2 2 0 FHIPEP family DUF4174 PF13778.1 CDJ69535.1 - 0.04 14.0 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) 7TM_GPCR_Srw PF10324.4 CDJ69537.1 - 0.063 12.4 7.7 0.084 11.9 5.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw SAPS PF04499.10 CDJ69537.1 - 0.35 9.4 24.5 0.41 9.2 17.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1168 PF06658.7 CDJ69537.1 - 1.1 8.8 37.8 0.45 10.0 13.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF3402 PF11882.3 CDJ69537.1 - 1.2 8.1 28.9 1.3 7.9 20.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) RIC3 PF15361.1 CDJ69537.1 - 2.3 8.4 33.2 5.4 7.2 23.0 1.6 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 YqfQ PF14181.1 CDJ69537.1 - 5.7 6.9 38.8 0.49 10.4 12.6 2.0 2 0 0 2 2 2 0 YqfQ-like protein FAM176 PF14851.1 CDJ69537.1 - 6 6.5 21.9 1.4 8.5 1.8 2.2 2 0 0 2 2 2 0 FAM176 family Apt1 PF10351.4 CDJ69538.1 - 0.28 10.0 2.4 0.32 9.8 1.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.8 CDJ69538.1 - 7.5 7.0 15.4 11 6.4 10.7 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Proteasome PF00227.21 CDJ69540.1 - 1.9e-31 108.8 0.3 1.1e-18 67.1 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit DUF4139 PF13598.1 CDJ69540.1 - 0.38 10.0 7.6 0.54 9.5 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Med3 PF11593.3 CDJ69540.1 - 1.6 7.9 16.2 2 7.5 11.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4139 PF13598.1 CDJ69541.1 - 0.32 10.2 3.8 0.33 10.2 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Herpes_capsid PF06112.6 CDJ69541.1 - 1.2 9.1 9.9 1.5 8.8 6.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FAM196 PF15265.1 CDJ69542.1 - 4.1 6.5 29.3 4.7 6.3 20.3 1.2 1 0 0 1 1 1 0 FAM196 family Radical_SAM PF04055.16 CDJ69543.1 - 5.2e-06 26.7 0.0 0.016 15.3 0.0 2.4 2 0 0 2 2 2 2 Radical SAM superfamily HemN_C PF06969.11 CDJ69543.1 - 0.0046 16.9 0.0 0.0046 16.9 0.0 3.2 4 0 0 4 4 4 1 HemN C-terminal domain Phage_rep_O PF04492.8 CDJ69544.1 - 0.17 12.1 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage replication protein O DUF456 PF04306.8 CDJ69546.1 - 0.01 15.8 4.6 0.02 14.9 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Hep_59 PF07052.6 CDJ69547.1 - 5.8e-20 71.5 1.7 5.8e-20 71.5 1.2 2.1 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Aminotran_1_2 PF00155.16 CDJ69549.1 - 2.9e-39 135.0 0.0 1.2e-38 133.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CDJ69549.1 - 0.03 13.4 0.0 0.067 12.3 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase DAO PF01266.19 CDJ69550.1 - 2.5e-39 135.2 0.0 3.8e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CDJ69550.1 - 4.5e-05 22.7 1.3 0.0041 16.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CDJ69550.1 - 0.00038 19.6 0.1 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 CDJ69550.1 - 0.0013 17.6 2.0 0.049 12.4 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 CDJ69550.1 - 0.0013 18.8 0.0 0.035 14.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDJ69550.1 - 0.014 15.3 0.0 0.55 10.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDJ69550.1 - 0.2 10.1 0.1 0.3 9.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ABC_tran PF00005.22 CDJ69551.1 - 2.7e-19 69.8 0.3 1.7e-18 67.2 0.0 2.5 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.18 CDJ69551.1 - 3.6e-15 56.1 1.7 3.6e-15 56.1 1.2 2.4 3 0 0 3 3 2 1 ABC transporter transmembrane region SbcCD_C PF13558.1 CDJ69551.1 - 1.9e-05 24.4 0.0 6.7e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 CDJ69551.1 - 9.1e-05 21.7 0.8 0.022 14.0 0.0 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CDJ69551.1 - 0.0002 21.3 0.5 0.0002 21.3 0.3 2.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CDJ69551.1 - 0.0032 17.6 0.0 0.074 13.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDJ69551.1 - 0.0041 16.6 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CDJ69551.1 - 0.013 16.3 0.0 0.027 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CDJ69551.1 - 0.014 14.8 0.2 0.035 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CDJ69551.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CDJ69551.1 - 0.2 11.5 0.0 0.78 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Patatin PF01734.17 CDJ69553.1 - 0.0038 17.1 2.4 0.013 15.4 1.7 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Glutaredoxin PF00462.19 CDJ69555.1 - 2.5e-12 46.5 0.0 4.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin LRR_4 PF12799.2 CDJ69556.1 - 6.6e-06 25.6 5.2 0.058 13.0 1.5 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CDJ69556.1 - 6.3e-05 22.5 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CDJ69556.1 - 0.052 13.3 6.8 4 7.2 0.0 2.6 2 1 1 3 3 3 0 Leucine rich repeat Exo_endo_phos PF03372.18 CDJ69557.1 - 2e-12 47.5 0.0 3.3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GpcrRhopsn4 PF10192.4 CDJ69557.1 - 7.2e-09 35.2 0.4 7.2e-09 35.2 0.3 1.5 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Med15 PF09606.5 CDJ69557.1 - 0.0016 16.7 44.7 0.0016 16.7 31.0 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal SGS PF05002.10 CDJ69558.1 - 1.1e-24 86.0 1.3 1.1e-24 86.0 0.9 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.11 CDJ69558.1 - 3.8e-13 49.7 7.2 4.2e-13 49.6 2.6 2.3 2 1 0 2 2 2 1 CS domain EF1_GNE PF00736.14 CDJ69558.1 - 0.29 10.8 1.8 0.9 9.2 0.1 2.4 2 1 1 3 3 3 0 EF-1 guanine nucleotide exchange domain OmpH PF03938.9 CDJ69561.1 - 0.11 12.4 38.1 8.4 6.3 26.4 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM176 PF14851.1 CDJ69561.1 - 0.12 12.0 1.2 0.49 10.0 0.4 2.1 2 0 0 2 2 2 0 FAM176 family Plasmodium_Vir PF05795.6 CDJ69561.1 - 0.98 8.5 2.6 1.3 8.1 1.5 1.6 1 1 1 2 2 2 0 Plasmodium vivax Vir protein RIC3 PF15361.1 CDJ69561.1 - 1.2 9.3 17.2 2.4 8.3 1.9 3.4 3 1 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 OATP PF03137.15 CDJ69561.1 - 1.4 6.9 5.9 4.3 5.2 2.0 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TMEM51 PF15345.1 CDJ69561.1 - 1.4 8.5 15.9 0.28 10.8 2.8 2.9 3 1 0 3 3 3 0 Transmembrane protein 51 Ctr PF04145.10 CDJ69561.1 - 5.9 6.9 12.4 0.58 10.2 0.8 3.0 3 0 0 3 3 3 0 Ctr copper transporter family Shadoo PF14999.1 CDJ69563.1 - 0.00046 20.0 7.1 0.00046 20.0 4.9 3.3 4 1 0 4 4 4 1 Shadow of prion protein, neuroprotective GSAP-16 PF14959.1 CDJ69563.1 - 0.058 13.1 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term DUF3373 PF11853.3 CDJ69563.1 - 0.079 11.4 3.0 0.13 10.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PseudoU_synth_2 PF00849.17 CDJ69564.1 - 7.2e-11 42.1 1.5 2e-10 40.7 0.0 2.2 1 1 1 2 2 2 1 RNA pseudouridylate synthase Med15 PF09606.5 CDJ69564.1 - 0.00057 18.2 22.2 0.039 12.1 1.6 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal ExoD PF06055.7 CDJ69564.1 - 0.0084 15.2 0.1 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD DUF2722 PF10846.3 CDJ69564.1 - 0.027 13.4 11.5 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) FimP PF09766.4 CDJ69564.1 - 0.057 12.4 9.9 0.62 9.0 2.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein Spt20 PF12090.3 CDJ69564.1 - 0.12 11.7 11.1 1.4 8.2 0.5 2.1 2 0 0 2 2 2 0 Spt20 family SeqA PF03925.8 CDJ69564.1 - 0.31 10.7 5.3 1.4 8.5 0.2 2.1 2 0 0 2 2 2 0 SeqA protein Pex14_N PF04695.8 CDJ69564.1 - 0.68 9.9 10.5 2.1 8.4 0.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region POP1 PF06978.6 CDJ69564.1 - 0.8 9.3 7.9 0.31 10.6 1.9 2.0 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Suf PF05843.9 CDJ69564.1 - 1.1 8.9 8.9 4.2 7.0 2.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FCP1_C PF09309.5 CDJ69564.1 - 1.9 7.6 11.5 0.3 10.3 1.3 2.2 2 0 0 2 2 2 0 FCP1, C-terminal RAB3GAP2_N PF14655.1 CDJ69564.1 - 2 7.3 10.8 5.2 5.9 0.3 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1840 PF08895.6 CDJ69564.1 - 2.5 8.1 6.9 6.3 6.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) PNRC PF15365.1 CDJ69564.1 - 3.2 7.8 12.7 0.34 10.9 1.0 2.4 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Gemini_AL2 PF01440.11 CDJ69564.1 - 6.9 6.7 13.4 7.3 6.6 2.1 2.1 2 0 0 2 2 2 0 Geminivirus AL2 protein Ribosomal_60s PF00428.14 CDJ69564.1 - 7.8 6.9 14.0 0.61 10.5 6.4 1.6 2 0 0 2 2 1 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDJ69565.1 - 0.066 11.4 37.6 0.085 11.0 26.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1631 PF07793.6 CDJ69565.1 - 0.28 9.2 29.0 0.34 8.9 20.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Med15 PF09606.5 CDJ69565.1 - 0.29 9.2 53.1 0.43 8.7 36.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_UL87 PF03043.9 CDJ69565.1 - 0.98 7.7 3.1 1.1 7.6 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family TFIIA PF03153.8 CDJ69565.1 - 2 8.2 24.9 2.7 7.7 17.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.10 CDJ69566.1 - 0.0016 17.6 11.1 0.0021 17.3 7.7 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit CD20 PF04103.10 CDJ69566.1 - 0.0037 17.2 1.6 1.1 9.1 1.0 3.2 1 1 0 1 1 1 1 CD20-like family SPX PF03105.14 CDJ69566.1 - 0.015 15.0 10.4 0.019 14.7 7.2 1.2 1 0 0 1 1 1 0 SPX domain FAM60A PF15396.1 CDJ69566.1 - 0.02 14.6 11.0 0.051 13.3 7.6 1.7 1 0 0 1 1 1 0 Protein Family FAM60A GAGA_bind PF06217.7 CDJ69566.1 - 0.19 11.6 20.0 0.37 10.6 13.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family SAGA-Tad1 PF12767.2 CDJ69566.1 - 0.28 10.7 20.9 0.028 14.0 10.6 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.9 CDJ69566.1 - 0.31 10.7 19.4 0.55 9.9 13.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF342 PF03961.8 CDJ69566.1 - 0.4 9.0 10.9 0.55 8.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2146 PF10220.4 CDJ69566.1 - 0.82 7.5 14.3 1.2 7.0 9.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Band_3_cyto PF07565.8 CDJ69566.1 - 1.1 8.6 16.6 1.8 8.0 11.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ctr PF04145.10 CDJ69566.1 - 1.2 9.1 12.9 1.6 8.7 6.1 3.0 2 1 0 2 2 2 0 Ctr copper transporter family Fmp27_WPPW PF10359.4 CDJ69566.1 - 2.1 6.6 21.0 2.9 6.2 14.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ycf1 PF05758.7 CDJ69566.1 - 2.4 5.7 16.6 3.1 5.3 11.5 1.0 1 0 0 1 1 1 0 Ycf1 Allexi_40kDa PF05549.6 CDJ69566.1 - 2.7 7.1 10.6 4.2 6.5 7.4 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DDHD PF02862.12 CDJ69566.1 - 3.6 7.3 16.6 6.5 6.4 11.1 1.6 2 0 0 2 2 2 0 DDHD domain HlyD_2 PF12700.2 CDJ69566.1 - 4.4 6.3 15.5 6.5 5.8 10.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein AUX_IAA PF02309.11 CDJ69566.1 - 4.6 6.9 13.6 9.8 5.8 9.4 1.5 1 0 0 1 1 1 0 AUX/IAA family YjgP_YjgQ PF03739.9 CDJ69566.1 - 6.7 5.3 7.4 13 4.4 5.2 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PAT1 PF09770.4 CDJ69566.1 - 7.4 4.6 56.6 0.039 12.2 32.9 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CLP_protease PF00574.18 CDJ69567.1 - 1.4e-10 41.1 0.4 1.9e-09 37.4 0.7 4.5 4 1 0 4 4 4 2 Clp protease YGGT PF02325.12 CDJ69568.1 - 0.0045 16.9 0.2 0.0094 15.8 0.1 1.5 1 0 0 1 1 1 1 YGGT family OmpH PF03938.9 CDJ69568.1 - 0.012 15.5 0.0 0.012 15.5 0.0 3.6 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) EPSP_synthase PF00275.15 CDJ69569.1 - 4.3e-25 87.9 9.8 8.7e-08 31.0 0.0 7.7 6 2 2 8 8 8 7 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CDJ69569.1 - 0.061 12.2 1.2 0.37 9.6 0.0 2.5 1 1 0 2 2 2 0 3-dehydroquinate synthase DUF3446 PF11928.3 CDJ69570.1 - 0.023 14.9 2.1 0.023 14.9 1.4 4.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3446) PGK PF00162.14 CDJ69571.1 - 4.5e-101 338.1 6.0 9.6e-64 215.3 1.0 2.0 1 1 1 2 2 2 2 Phosphoglycerate kinase TAXi_C PF14541.1 CDJ69571.1 - 0.066 12.7 0.2 8.6 5.8 0.1 2.7 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal MSP1_C PF07462.6 CDJ69571.1 - 1.8 6.8 12.6 0.0071 14.7 2.3 1.5 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus NAC PF01849.13 CDJ69572.1 - 2.6e-18 65.2 0.0 5e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 CDJ69572.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CDJ69572.1 - 0.0063 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Dermcidin PF15291.1 CDJ69572.1 - 0.013 15.7 5.3 0.1 12.7 0.8 2.3 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide DUF2753 PF10952.3 CDJ69572.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) CDC45 PF02724.9 CDJ69572.1 - 3.2 5.6 4.6 4.1 5.3 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 CDJ69573.1 - 1.8e-25 89.6 0.0 8.6e-12 44.7 0.1 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69573.1 - 2.2e-08 33.4 0.0 0.00082 18.5 0.0 2.3 1 1 2 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CDJ69573.1 - 0.00098 18.1 0.1 0.017 14.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CDJ69573.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lon_C PF05362.8 CDJ69574.1 - 3.1e-35 121.3 0.6 7.9e-18 64.5 0.0 3.2 2 1 1 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CDJ69574.1 - 1e-17 64.5 0.0 4.5e-17 62.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CDJ69574.1 - 2.6e-14 53.3 0.2 4e-08 33.1 0.2 2.5 2 0 0 2 2 2 2 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 CDJ69574.1 - 6.9e-07 29.0 0.0 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 CDJ69574.1 - 3.1e-06 26.1 0.0 5.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 CDJ69574.1 - 3e-05 24.8 0.0 0.00011 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDJ69574.1 - 3.3e-05 24.0 0.1 0.00057 20.0 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CDJ69574.1 - 7.9e-05 22.7 0.0 7.9e-05 22.7 0.0 4.0 3 1 0 3 3 1 1 AAA ATPase domain MobB PF03205.9 CDJ69574.1 - 0.0005 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CDJ69574.1 - 0.00051 20.3 0.2 0.03 14.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CDJ69574.1 - 0.00085 18.7 0.0 0.0024 17.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 CDJ69574.1 - 0.0012 17.8 0.8 0.0021 17.1 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CDJ69574.1 - 0.006 16.4 0.0 0.006 16.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 CDJ69574.1 - 0.016 14.6 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 CDJ69574.1 - 0.022 14.6 0.0 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDJ69574.1 - 0.028 14.5 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CDJ69574.1 - 2.2 8.2 0.0 2.2 8.2 0.0 3.8 3 0 0 3 3 2 0 AAA domain DUF1510 PF07423.6 CDJ69574.1 - 5.2 6.3 27.0 6.2 6.1 11.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Gly-zipper_OmpA PF13436.1 CDJ69576.1 - 0.035 13.7 7.1 0.058 13.0 4.9 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain 2OG-FeII_Oxy_3 PF13640.1 CDJ69577.1 - 9e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CDJ69577.1 - 0.00088 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CDJ69577.1 - 0.005 16.4 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4613 PF15390.1 CDJ69578.1 - 0.16 10.1 3.3 0.17 9.9 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF755 PF05501.6 CDJ69578.1 - 0.38 10.8 16.2 0.49 10.4 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Plasmodium_Vir PF05795.6 CDJ69578.1 - 0.4 9.8 1.2 0.48 9.5 0.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SR-25 PF10500.4 CDJ69578.1 - 0.58 9.6 15.3 0.44 9.9 9.8 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein UPF0560 PF10577.4 CDJ69578.1 - 1.7 6.7 12.9 2 6.5 8.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2217 PF10265.4 CDJ69578.1 - 6.8 5.3 10.4 7.5 5.1 7.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Mcm10 PF09332.6 CDJ69578.1 - 7.1 5.8 17.0 8.1 5.6 11.8 1.0 1 0 0 1 1 1 0 Mcm10 replication factor Dehydrin PF00257.14 CDJ69578.1 - 7.8 6.8 10.0 14 6.0 7.0 1.4 1 0 0 1 1 1 0 Dehydrin Band_7 PF01145.20 CDJ69579.1 - 3.7e-29 101.9 0.0 6.8e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CDJ69579.1 - 0.081 12.4 0.0 0.18 11.2 0.0 1.6 1 1 0 1 1 1 0 SPFH domain-Band 7 family Arf PF00025.16 CDJ69580.1 - 8.7e-21 73.9 0.0 7.6e-13 48.0 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CDJ69580.1 - 0.046 14.2 0.0 0.074 13.5 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein KOW PF00467.24 CDJ69581.1 - 0.00012 21.6 0.1 0.00017 21.2 0.1 1.2 1 0 0 1 1 1 1 KOW motif rRNA_proc-arch PF13234.1 CDJ69581.1 - 0.14 11.2 0.0 0.16 11.0 0.0 1.0 1 0 0 1 1 1 0 rRNA-processing arch domain ER_lumen_recept PF00810.13 CDJ69582.1 - 1.1e-22 81.0 12.3 8e-22 78.3 8.5 2.1 1 1 0 1 1 1 1 ER lumen protein retaining receptor EMP70 PF02990.11 CDJ69583.1 - 2e-82 277.3 6.4 2.4e-81 273.7 4.4 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 Spt20 PF12090.3 CDJ69583.1 - 0.047 13.0 0.4 0.096 12.0 0.2 1.5 2 0 0 2 2 2 0 Spt20 family DUF3169 PF11368.3 CDJ69583.1 - 0.13 11.4 1.6 4.4 6.4 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF912 PF06024.7 CDJ69583.1 - 0.31 11.0 1.4 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Nol1_Nop2_Fmu PF01189.12 CDJ69585.1 - 6.1e-32 111.1 0.0 2.5e-30 105.8 0.0 2.7 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CDJ69585.1 - 9.7e-10 38.2 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CDJ69585.1 - 2.5e-08 33.3 0.0 3.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CDJ69585.1 - 1e-06 28.7 0.0 3.1e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDJ69585.1 - 3.9e-06 26.3 0.0 2.3e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 CDJ69585.1 - 0.00012 21.6 0.0 0.00038 20.0 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 CDJ69585.1 - 0.00028 21.4 0.0 0.00062 20.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ69585.1 - 0.00052 20.3 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 CDJ69585.1 - 0.0027 17.2 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CDJ69585.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 CDJ69585.1 - 0.037 14.5 0.0 0.098 13.1 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain PrmA PF06325.8 CDJ69585.1 - 0.081 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 CDJ69585.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 CDJ69585.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 CDJ69585.1 - 0.15 12.5 0.0 0.45 11.0 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Skp1_POZ PF03931.10 CDJ69586.1 - 4.8e-09 36.1 0.0 1.4e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain ERp29 PF07749.7 CDJ69586.1 - 0.069 13.7 0.1 0.13 12.8 0.0 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain zf-C4H2 PF10146.4 CDJ69586.1 - 0.17 11.8 0.2 0.23 11.4 0.2 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3682 PF12446.3 CDJ69586.1 - 1.3 9.3 8.8 1.6 9.0 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Patatin PF01734.17 CDJ69587.1 - 7.8e-30 104.3 1.4 7.8e-30 104.3 1.0 4.4 4 2 0 4 4 4 1 Patatin-like phospholipase V_ATPase_I PF01496.14 CDJ69588.1 - 2.4 5.8 6.9 2.4 5.8 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 CDJ69588.1 - 4.4 6.9 15.3 4.7 6.8 10.6 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4407 PF14362.1 CDJ69588.1 - 6.8 5.5 17.0 7.3 5.4 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 CDJ69588.1 - 9.9 5.0 10.4 12 4.7 7.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myosin_head PF00063.16 CDJ69590.1 - 4.8e-167 557.0 0.0 4.8e-157 523.9 0.0 2.3 1 1 1 2 2 2 2 Myosin head (motor domain) MyTH4 PF00784.12 CDJ69590.1 - 1.2e-11 44.4 0.0 6e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 MyTH4 domain IQ PF00612.22 CDJ69590.1 - 0.00094 18.6 0.4 0.003 17.0 0.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Zeta_toxin PF06414.7 CDJ69590.1 - 0.0031 16.6 0.5 0.0071 15.4 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 CDJ69590.1 - 0.021 14.8 0.0 0.021 14.8 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain tRNA_m1G_MT PF01746.16 CDJ69591.1 - 3.9e-17 62.4 0.0 1e-16 61.0 0.0 1.8 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Ribosomal_L1 PF00687.16 CDJ69592.1 - 3.6e-43 147.4 0.0 3.6e-43 147.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Acyl-CoA_dh_1 PF00441.19 CDJ69593.1 - 2.5e-25 89.3 4.9 3.7e-25 88.8 3.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CDJ69593.1 - 9.5e-23 79.4 0.3 1.9e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Peptidase_C97 PF05903.9 CDJ69593.1 - 1.5e-17 63.7 0.0 2.2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Acyl-CoA_dh_2 PF08028.6 CDJ69593.1 - 4.4e-06 26.9 1.9 7.3e-06 26.2 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1386 PF07138.6 CDJ69593.1 - 0.036 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) LRAT PF04970.8 CDJ69593.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Rpr2 PF04032.11 CDJ69594.1 - 2.4e-05 24.1 0.1 0.0003 20.5 0.0 2.9 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TPR_11 PF13414.1 CDJ69595.1 - 2.5e-11 43.0 2.5 6.5e-08 32.1 0.3 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CDJ69595.1 - 4e-05 23.2 5.0 0.044 13.6 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ69595.1 - 4.9e-05 22.7 3.5 0.028 14.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ69595.1 - 0.0001 22.5 0.6 0.002 18.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ69595.1 - 0.00053 20.5 0.7 0.00053 20.5 0.5 4.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CDJ69595.1 - 0.023 14.7 2.7 0.054 13.6 0.7 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CDJ69595.1 - 0.063 13.2 2.1 1.2 9.1 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ69595.1 - 0.075 13.7 2.6 0.78 10.5 0.2 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ69595.1 - 0.52 10.2 4.9 0.23 11.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDJ69595.1 - 0.58 10.7 7.5 7.1 7.3 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol3_delta2 PF13177.1 CDJ69597.1 - 3.2e-15 56.1 0.0 1.5e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CDJ69597.1 - 8.2e-15 55.1 0.0 1.9e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CDJ69597.1 - 3.5e-07 29.2 0.0 0.0038 15.9 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CDJ69597.1 - 2.6e-06 27.5 0.0 8.2e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CDJ69597.1 - 2.1e-05 23.4 0.0 0.0035 16.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 CDJ69597.1 - 2.8e-05 24.0 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CDJ69597.1 - 8.6e-05 21.6 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CDJ69597.1 - 0.00011 22.2 0.1 0.00099 19.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 CDJ69597.1 - 0.00015 21.5 0.0 0.0021 17.7 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase ArgK PF03308.11 CDJ69597.1 - 0.00021 20.1 0.2 0.082 11.6 0.0 2.5 2 1 1 3 3 3 2 ArgK protein Mg_chelatase PF01078.16 CDJ69597.1 - 0.00027 20.1 0.0 0.0011 18.1 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 CDJ69597.1 - 0.00033 19.7 0.0 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 CDJ69597.1 - 0.00037 20.0 0.1 0.002 17.6 0.1 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 CDJ69597.1 - 0.00041 19.9 0.1 0.0038 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CDJ69597.1 - 0.00042 19.9 0.0 0.0026 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CDJ69597.1 - 0.00063 19.2 0.4 0.0029 17.0 0.0 2.3 2 1 1 3 3 3 1 FtsK/SpoIIIE family Zot PF05707.7 CDJ69597.1 - 0.0008 18.9 0.0 0.0017 17.8 0.0 1.5 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.1 CDJ69597.1 - 0.0011 18.6 4.1 0.0027 17.3 0.0 3.5 3 2 2 5 5 4 1 Part of AAA domain AAA_25 PF13481.1 CDJ69597.1 - 0.0014 18.0 0.0 0.005 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CDJ69597.1 - 0.0014 17.8 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 CDJ69597.1 - 0.0015 18.2 0.1 0.0094 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CDJ69597.1 - 0.0025 17.7 0.0 0.0074 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CDJ69597.1 - 0.0049 17.6 0.0 0.012 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDJ69597.1 - 0.0052 17.0 0.0 0.0089 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CDJ69597.1 - 0.011 15.6 0.0 0.055 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 CDJ69597.1 - 0.015 15.2 0.0 0.038 13.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) DEAD PF00270.24 CDJ69597.1 - 0.019 14.4 0.0 5 6.5 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase S6PP PF05116.8 CDJ69597.1 - 0.03 13.6 0.1 0.069 12.4 0.0 1.6 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase IstB_IS21 PF01695.12 CDJ69597.1 - 0.048 13.0 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 CDJ69597.1 - 0.057 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CDJ69597.1 - 0.077 13.0 0.0 4.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 CDJ69597.1 - 0.095 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-AN1 PF01428.11 CDJ69598.1 - 4.9e-11 42.3 8.5 1e-10 41.3 5.9 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CDJ69598.1 - 0.013 15.7 5.1 0.028 14.6 3.5 1.6 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain IBR PF01485.16 CDJ69598.1 - 6.2 6.7 11.0 5.1 7.0 5.9 2.1 2 1 0 2 2 2 0 IBR domain GTP_EFTU PF00009.22 CDJ69599.1 - 5.7e-62 208.5 0.1 8.5e-62 207.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CDJ69599.1 - 8.6e-36 122.1 0.0 3.3e-35 120.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CDJ69599.1 - 1.4e-18 66.4 0.0 3e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CDJ69599.1 - 1.2e-14 53.8 0.0 3.3e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CDJ69599.1 - 3.5e-12 46.2 0.1 9.4e-12 44.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDJ69599.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CDJ69599.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Myosin_head PF00063.16 CDJ69600.1 - 1.7e-161 538.6 0.3 2.6e-129 432.3 0.1 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.1 CDJ69600.1 - 0.018 15.1 0.0 0.071 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 CDJ69600.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 CDJ69600.1 - 0.024 13.7 0.1 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CDJ69600.1 - 0.03 14.0 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 CDJ69600.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 CDJ69600.1 - 0.081 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 CDJ69600.1 - 0.095 12.8 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase T2SE PF00437.15 CDJ69600.1 - 0.12 11.2 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 CDJ69600.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CDJ69600.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 CDJ69601.1 - 3e-21 75.5 0.1 3e-16 59.5 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDJ69601.1 - 4.8e-18 64.7 0.2 1.9e-06 27.9 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDJ69601.1 - 8.2e-16 58.0 0.1 2.7e-10 40.4 0.0 3.3 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CDJ69601.1 - 1.7e-15 55.9 5.7 2.7e-07 30.0 0.0 4.2 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CDJ69601.1 - 3.2e-12 45.4 0.3 0.00017 21.4 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Sigma70_r4_2 PF08281.7 CDJ69604.1 - 0.13 11.6 1.0 3.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Sigma-70, region 4 RHD3 PF05879.7 CDJ69606.1 - 1.2e-108 364.0 0.0 1.6e-108 363.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 CDJ69606.1 - 0.00093 19.0 2.1 0.0012 18.6 0.2 2.1 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CDJ69606.1 - 0.0029 17.5 0.0 0.0085 16.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.13 CDJ69606.1 - 0.0096 14.9 0.1 0.023 13.6 0.1 1.6 1 0 0 1 1 1 1 Septin GBP PF02263.14 CDJ69606.1 - 0.014 14.5 0.1 0.047 12.7 0.1 1.9 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_21 PF13304.1 CDJ69606.1 - 0.071 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CDJ69606.1 - 0.075 13.5 0.1 0.24 11.9 0.1 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 CDJ69606.1 - 0.13 12.2 3.0 0.65 9.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 CDJ69606.1 - 0.43 10.8 0.1 0.43 10.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain PI-PLC-X PF00388.14 CDJ69607.1 - 0.0017 17.7 0.0 0.0047 16.3 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain tRNA-synt_1c PF00749.16 CDJ69608.1 - 8.7e-100 333.4 0.0 1.1e-99 333.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CDJ69608.1 - 6.1e-36 123.6 0.0 3.5e-35 121.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CDJ69608.1 - 0.0005 20.5 0.1 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CDJ69608.1 - 0.019 14.8 0.1 0.052 13.4 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CDJ69608.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NAD_binding_8 PF13450.1 CDJ69609.1 - 0.17 11.8 1.1 0.53 10.3 0.8 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TF_Zn_Ribbon PF08271.7 CDJ69610.1 - 0.0026 17.0 0.1 0.0068 15.6 0.1 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding RPA_interact_C PF14768.1 CDJ69610.1 - 0.036 14.4 1.1 0.075 13.4 0.3 1.9 2 0 0 2 2 2 0 Replication protein A interacting C-terminal Rad50_zn_hook PF04423.9 CDJ69610.1 - 0.037 13.4 1.5 5.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif Miro PF08477.8 CDJ69611.1 - 6.6e-05 23.3 0.0 0.19 12.2 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 CDJ69611.1 - 0.0076 15.6 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 2 Ras family AAA_16 PF13191.1 CDJ69611.1 - 0.0088 16.0 0.7 0.014 15.3 0.1 1.6 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 CDJ69611.1 - 0.055 12.9 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 CDJ69611.1 - 0.067 12.2 0.1 0.099 11.7 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin DUF3987 PF13148.1 CDJ69611.1 - 0.082 11.4 0.4 0.15 10.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_33 PF13671.1 CDJ69611.1 - 0.096 12.5 0.3 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2984 PF11203.3 CDJ69613.1 - 0.024 14.7 1.9 0.024 14.7 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2984) APC_CDC26 PF10471.4 CDJ69613.1 - 0.036 14.7 9.1 0.44 11.3 1.6 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 SpaB_C PF14028.1 CDJ69613.1 - 0.29 10.6 18.7 0.33 10.4 12.7 1.3 1 1 0 1 1 1 0 SpaB C-terminal domain APH PF01636.18 CDJ69613.1 - 1.1 8.8 14.0 1.6 8.4 9.7 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUFU_C PF12470.3 CDJ69614.1 - 1.3 8.6 3.4 1.1 8.8 0.8 1.8 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain McyA_C PF12593.3 CDJ69615.1 - 0.12 12.1 3.4 0.18 11.5 0.1 2.8 2 0 0 2 2 2 0 Microcystin synthetase C terminal SR-25 PF10500.4 CDJ69615.1 - 0.51 9.7 26.0 0.016 14.6 12.9 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein UPF0253 PF06786.7 CDJ69616.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) BBS2_C PF14782.1 CDJ69619.1 - 0.028 12.9 2.7 0.047 12.2 1.8 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Tmemb_cc2 PF10267.4 CDJ69620.1 - 0.0031 16.1 10.2 0.0031 16.1 7.1 1.8 1 1 1 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein APG6 PF04111.7 CDJ69620.1 - 0.0041 16.2 5.3 0.0041 16.2 3.6 2.2 2 0 0 2 2 2 1 Autophagy protein Apg6 DUF4446 PF14584.1 CDJ69620.1 - 0.013 15.3 0.8 0.013 15.3 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) RAP1 PF07218.6 CDJ69620.1 - 0.1 10.6 5.1 0.12 10.4 3.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TBPIP PF07106.8 CDJ69620.1 - 0.53 9.8 18.4 0.07 12.6 6.1 2.5 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Herpes_capsid PF06112.6 CDJ69620.1 - 1 9.3 13.3 2.5 8.1 9.2 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Phage_GP20 PF06810.6 CDJ69620.1 - 8.9 5.7 21.7 0.032 13.6 5.1 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 Dehydratase_MU PF02288.10 CDJ69621.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Dehydratase medium subunit DUF1908 PF08926.6 CDJ69622.1 - 0.016 14.0 3.5 0.019 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) SR-25 PF10500.4 CDJ69622.1 - 0.16 11.3 9.7 0.19 11.1 6.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ69622.1 - 0.78 9.7 10.4 1.1 9.3 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF1013 PF06242.6 CDJ69623.1 - 0.0092 15.9 3.6 0.073 13.0 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1013) TFIIIC_delta PF12657.2 CDJ69623.1 - 0.5 10.0 8.8 2 8.1 6.1 1.8 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Saw1 PF11561.3 CDJ69623.1 - 0.97 8.7 8.5 2.1 7.6 5.9 1.7 1 1 0 1 1 1 0 Single strand annealing-weakened 1 zf-C3HC4_3 PF13920.1 CDJ69624.1 - 1.4e-06 27.8 7.3 2.7e-06 26.9 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ69624.1 - 0.17 11.9 9.7 0.35 10.9 6.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TF_Zn_Ribbon PF08271.7 CDJ69626.1 - 4.7e-09 35.4 4.1 6e-09 35.0 2.8 1.1 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 CDJ69626.1 - 0.0049 16.2 1.6 0.0086 15.5 1.1 1.4 1 0 0 1 1 1 1 A2L zinc ribbon domain TrbL PF04610.9 CDJ69626.1 - 0.037 13.7 7.0 0.037 13.7 4.8 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Glyco_trans_2_3 PF13632.1 CDJ69626.1 - 0.067 12.8 2.6 0.087 12.5 1.8 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Lar_restr_allev PF14354.1 CDJ69626.1 - 0.14 12.4 1.8 0.22 11.8 1.3 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar FA_desaturase PF00487.19 CDJ69626.1 - 0.27 10.6 7.9 0.29 10.5 5.5 1.0 1 0 0 1 1 1 0 Fatty acid desaturase zf-ribbon_3 PF13248.1 CDJ69626.1 - 0.32 10.2 3.9 0.7 9.1 2.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CDJ69626.1 - 0.46 10.3 3.8 0.68 9.7 2.6 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CDJ69626.1 - 0.73 9.5 4.0 1.1 8.9 2.8 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain YhfH PF14149.1 CDJ69626.1 - 0.84 9.4 6.4 6.4 6.6 0.2 2.2 1 1 1 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.5 CDJ69626.1 - 3.6 7.6 6.4 2.1 8.3 0.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF1469 PF07332.6 CDJ69626.1 - 4.4 7.0 17.8 7.8 6.2 12.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) SdpI PF13630.1 CDJ69626.1 - 9.8 5.9 12.7 18 5.1 8.8 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family PRA1 PF03208.14 CDJ69627.1 - 7.8e-22 77.2 0.1 9.9e-22 76.9 0.1 1.1 1 0 0 1 1 1 1 PRA1 family protein KH_1 PF00013.24 CDJ69628.1 - 2.5e-19 68.6 0.0 9.1e-07 28.4 0.0 5.7 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 CDJ69628.1 - 2.9e-08 33.1 0.1 0.1 12.2 0.0 4.7 5 0 0 5 5 5 2 KH domain BMC PF00936.14 CDJ69628.1 - 0.0068 16.0 6.1 0.31 10.7 0.0 5.3 6 0 0 6 6 6 1 BMC domain KH_2 PF07650.12 CDJ69628.1 - 0.017 14.6 3.5 1.2 8.7 0.0 3.4 3 0 0 3 3 3 0 KH domain Relaxase PF03432.9 CDJ69629.1 - 0.013 14.9 1.5 0.013 14.9 1.1 2.4 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain DUF948 PF06103.6 CDJ69629.1 - 2.8 7.8 8.5 11 6.0 0.2 4.1 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) HALZ PF02183.13 CDJ69629.1 - 5.5 6.7 14.0 0.069 12.8 0.4 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 CDJ69629.1 - 5.7 6.6 43.2 0.17 11.5 8.2 4.8 4 1 1 5 5 5 0 TPR/MLP1/MLP2-like protein DUF2422 PF10337.4 CDJ69631.1 - 0.37 9.5 2.2 0.49 9.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FLO_LFY PF01698.11 CDJ69631.1 - 0.66 8.7 5.9 0.77 8.5 4.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4483 PF14825.1 CDJ69631.1 - 2 8.0 11.6 1.1 8.8 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) DUF3807 PF12720.2 CDJ69631.1 - 3 7.9 15.2 0.037 14.1 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3807) DUF4407 PF14362.1 CDJ69631.1 - 6.2 5.6 12.4 8.1 5.3 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APC_CDC26 PF10471.4 CDJ69631.1 - 7.8 7.3 21.5 5.3 7.8 7.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Surface_antigen PF11054.3 CDJ69632.1 - 1.5e-60 204.7 6.2 1.8e-60 204.4 4.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen TPR_11 PF13414.1 CDJ69632.1 - 0.0099 15.5 1.3 0.011 15.3 0.1 1.6 2 0 0 2 2 2 1 TPR repeat Surface_antigen PF11054.3 CDJ69633.1 - 7.5e-62 209.0 0.0 9.8e-62 208.6 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen AAA_27 PF13514.1 CDJ69634.1 - 0.00012 19.9 12.6 0.0037 15.0 5.2 2.0 2 0 0 2 2 2 2 AAA domain Sec20 PF03908.8 CDJ69634.1 - 0.0025 17.4 1.5 0.0025 17.4 1.1 4.2 4 1 1 5 5 5 2 Sec20 TBCA PF02970.11 CDJ69634.1 - 0.0078 16.2 3.9 1.6 8.8 0.0 3.1 3 0 0 3 3 3 2 Tubulin binding cofactor A Sugarporin_N PF11471.3 CDJ69634.1 - 0.29 10.8 7.6 4.1 7.1 0.7 2.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension WD40 PF00400.27 CDJ69636.1 - 2.1e-16 59.0 9.6 0.00098 18.9 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nbas_N PF15492.1 CDJ69636.1 - 0.016 14.3 1.8 0.31 10.0 0.2 3.3 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Spt20 PF12090.3 CDJ69636.1 - 0.044 13.1 2.2 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Spt20 family BBS2_N PF14781.1 CDJ69636.1 - 0.29 10.7 2.0 1.4 8.5 0.1 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal RAB3GAP2_N PF14655.1 CDJ69636.1 - 0.9 8.4 0.0 0.9 8.4 0.0 3.6 2 2 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDJ69636.1 - 2.8 6.9 13.5 0.49 9.4 0.5 2.2 2 0 0 2 2 2 0 Fms-interacting protein DUF4557 PF15101.1 CDJ69636.1 - 6.8 6.4 13.7 16 5.2 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Serpin PF00079.15 CDJ69637.1 - 4.8e-41 141.1 2.8 5.6e-22 78.3 2.1 2.3 2 1 0 2 2 2 2 Serpin (serine protease inhibitor) DUF3446 PF11928.3 CDJ69637.1 - 0.13 12.5 7.3 0.41 10.8 5.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) CAF-1_p150 PF11600.3 CDJ69637.1 - 0.32 10.3 9.9 0.53 9.6 6.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Serinc PF03348.10 CDJ69637.1 - 0.62 8.7 1.8 0.95 8.1 1.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2366 PF10171.4 CDJ69638.1 - 0.15 11.5 2.9 0.34 10.3 2.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) SR-25 PF10500.4 CDJ69639.1 - 0.00039 19.9 4.9 0.00041 19.8 3.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein P12 PF12669.2 CDJ69639.1 - 0.044 13.9 7.6 0.052 13.7 5.3 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Med15 PF09606.5 CDJ69639.1 - 1.4 6.9 37.8 1.6 6.7 26.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gastrin PF00918.12 CDJ69639.1 - 2.1 9.1 13.7 2.7 8.8 9.5 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF3373 PF11853.3 CDJ69639.1 - 2.3 6.6 7.6 2.6 6.4 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TEX13 PF15186.1 CDJ69639.1 - 4.4 6.8 14.6 4.9 6.7 10.1 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF3573 PF12097.3 CDJ69639.1 - 5 5.6 9.9 5.7 5.4 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TCL1_MTCP1 PF01840.12 CDJ69639.1 - 5.8 6.4 11.1 9.3 5.7 7.7 1.5 1 1 0 1 1 1 0 TCL1/MTCP1 family Cellulose_synt PF03552.9 CDJ69639.1 - 6.1 5.0 6.1 6.9 4.8 4.2 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4557 PF15101.1 CDJ69639.1 - 6.2 6.6 15.9 7.2 6.3 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RNA_capsid PF03035.9 CDJ69639.1 - 6.8 6.4 11.6 6.8 6.4 8.0 1.1 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein IncA PF04156.9 CDJ69639.1 - 9.5 5.7 26.4 11 5.6 18.3 1.1 1 0 0 1 1 1 0 IncA protein Abhydrolase_5 PF12695.2 CDJ69640.1 - 1.3e-09 37.9 0.5 1.3e-09 37.9 0.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ69640.1 - 9.5e-05 22.3 4.1 9.5e-05 22.3 2.8 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CDJ69640.1 - 0.0016 18.0 1.1 0.0016 18.0 0.7 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ribosomal_60s PF00428.14 CDJ69640.1 - 0.023 15.0 29.1 0.12 12.7 3.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DEC-1_N PF04625.8 CDJ69640.1 - 0.31 9.6 13.8 1.7 7.2 0.2 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF3235 PF11574.3 CDJ69640.1 - 3 8.1 15.5 7.5 6.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Shadoo PF14999.1 CDJ69640.1 - 5.4 6.8 21.2 7.1 6.4 5.6 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF1180 PF06679.7 CDJ69640.1 - 9.9 6.0 6.9 22 4.9 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Ribosomal_60s PF00428.14 CDJ69641.1 - 6.4 7.2 15.4 16 5.9 10.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Kinesin PF00225.18 CDJ69643.1 - 2.7e-61 207.1 0.2 2.7e-61 207.1 0.1 2.8 2 1 1 3 3 3 1 Kinesin motor domain V_ATPase_I PF01496.14 CDJ69643.1 - 0.0022 15.9 7.6 0.0027 15.6 5.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ORF6C PF10552.4 CDJ69643.1 - 0.0026 17.4 5.4 0.0066 16.1 3.7 1.6 1 0 0 1 1 1 1 ORF6C domain GAS PF13851.1 CDJ69643.1 - 0.0044 16.2 18.3 0.0044 16.2 12.7 1.6 2 0 0 2 2 1 1 Growth-arrest specific micro-tubule binding TMCO5 PF14992.1 CDJ69643.1 - 0.0046 16.1 15.0 0.0068 15.5 10.4 1.3 1 0 0 1 1 1 1 TMCO5 family Phage_GP20 PF06810.6 CDJ69643.1 - 0.012 15.0 17.4 0.027 13.8 12.1 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.4 CDJ69643.1 - 0.05 13.4 16.6 0.1 12.4 11.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 CDJ69643.1 - 0.05 13.6 16.3 0.042 13.8 9.7 2.2 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 CDJ69643.1 - 0.053 11.9 9.1 0.088 11.2 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Occludin_ELL PF07303.8 CDJ69643.1 - 0.059 14.0 14.0 0.089 13.5 9.3 1.7 2 0 0 2 2 1 0 Occludin homology domain NPV_P10 PF05531.7 CDJ69643.1 - 0.07 13.3 5.2 0.26 11.5 3.0 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.6 CDJ69643.1 - 0.084 11.3 15.1 0.16 10.4 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Orthopox_A5L PF06193.6 CDJ69643.1 - 0.096 12.6 9.8 0.072 13.0 4.9 2.1 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like Filament PF00038.16 CDJ69643.1 - 0.12 11.7 16.2 0.21 11.0 10.7 1.8 1 1 1 2 2 2 0 Intermediate filament protein MAD PF05557.8 CDJ69643.1 - 0.15 10.1 13.7 0.2 9.6 9.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Tnp_P_element PF12017.3 CDJ69643.1 - 0.15 11.2 4.2 0.28 10.4 2.9 1.4 1 0 0 1 1 1 0 Transposase protein APG6 PF04111.7 CDJ69643.1 - 0.16 10.9 13.4 0.28 10.1 9.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 CDJ69643.1 - 0.17 12.0 10.1 0.26 11.4 5.7 2.4 2 0 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.16 CDJ69643.1 - 0.24 11.7 11.5 0.45 10.8 7.2 2.1 2 0 0 2 2 1 0 Spectrin repeat Sec34 PF04136.10 CDJ69643.1 - 0.25 11.0 6.1 0.71 9.5 4.2 1.9 1 0 0 1 1 1 0 Sec34-like family Spc7 PF08317.6 CDJ69643.1 - 0.3 9.7 12.7 0.59 8.7 8.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Tup_N PF08581.5 CDJ69643.1 - 0.37 10.9 11.2 0.96 9.6 7.8 1.7 1 0 0 1 1 1 0 Tup N-terminal DASH_Dam1 PF08653.5 CDJ69643.1 - 0.39 10.5 1.5 0.62 9.8 0.4 1.9 2 0 0 2 2 1 0 DASH complex subunit Dam1 Sas10_Utp3 PF04000.10 CDJ69643.1 - 0.43 10.8 4.3 4.9 7.4 1.5 2.8 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Reo_sigmaC PF04582.7 CDJ69643.1 - 0.44 9.6 6.3 0.093 11.8 0.3 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein COG2 PF06148.6 CDJ69643.1 - 0.47 10.3 8.6 0.31 10.9 4.2 2.0 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2935 PF11155.3 CDJ69643.1 - 0.54 10.3 5.6 1 9.4 3.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF2935) NMT_C PF02799.10 CDJ69643.1 - 0.54 9.5 3.9 0.99 8.7 2.7 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Laminin_II PF06009.7 CDJ69643.1 - 0.58 9.9 12.9 0.12 12.1 5.9 2.2 2 0 0 2 2 1 0 Laminin Domain II zf-C4H2 PF10146.4 CDJ69643.1 - 0.59 10.1 9.8 1.6 8.6 5.2 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein DUF3508 PF12018.3 CDJ69643.1 - 0.66 8.9 10.1 1 8.2 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) BRE1 PF08647.6 CDJ69643.1 - 0.69 9.9 18.4 1.3 9.0 11.6 2.4 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase DUF4201 PF13870.1 CDJ69643.1 - 0.69 9.3 15.7 2.3 7.6 10.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Dabb PF07876.7 CDJ69643.1 - 0.82 10.1 3.4 39 4.7 0.0 3.6 3 1 0 3 3 3 0 Stress responsive A/B Barrel Domain bZIP_1 PF00170.16 CDJ69643.1 - 0.95 9.4 13.1 0.06 13.3 4.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor Fib_alpha PF08702.5 CDJ69643.1 - 0.96 9.5 10.9 1.8 8.6 0.9 2.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 CDJ69643.1 - 1 9.7 10.4 1.4 9.2 6.2 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 CDJ69643.1 - 1.2 8.7 15.4 2.4 7.7 10.6 1.4 1 0 0 1 1 1 0 Mnd1 family DUF4298 PF14131.1 CDJ69643.1 - 1.6 8.6 7.2 23 4.9 5.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) DivIC PF04977.10 CDJ69643.1 - 1.6 8.2 16.4 0.64 9.5 3.0 2.9 2 1 1 3 3 2 0 Septum formation initiator CENP-Q PF13094.1 CDJ69643.1 - 2 8.4 17.5 2 8.4 4.4 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF724 PF05266.9 CDJ69643.1 - 2.1 7.9 14.1 3.1 7.3 9.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.8 CDJ69643.1 - 2.2 7.2 9.5 2.9 6.8 5.9 1.6 2 0 0 2 2 2 0 TMPIT-like protein DUF3452 PF11934.3 CDJ69643.1 - 2.2 7.5 5.1 5.5 6.3 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) DUF4315 PF14193.1 CDJ69643.1 - 2.2 8.2 15.4 2.6 8.0 9.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) Rox3 PF08633.5 CDJ69643.1 - 2.3 8.5 9.8 7.1 6.9 0.9 3.2 2 1 1 3 3 3 0 Rox3 mediator complex subunit SseC PF04888.7 CDJ69643.1 - 3.2 7.0 27.3 3.3 6.9 3.6 2.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family TPR_MLP1_2 PF07926.7 CDJ69643.1 - 6 6.6 20.5 28 4.4 14.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.4 CDJ69643.1 - 8 6.7 8.2 44 4.3 5.7 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3450 PF11932.3 CDJ69643.1 - 8.9 5.4 23.6 0.27 10.4 9.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4208 PF13907.1 CDJ69643.1 - 9 6.5 12.5 51 4.1 5.6 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4208) Exonuc_VII_L PF02601.10 CDJ69645.1 - 0.25 10.5 12.3 0.41 9.7 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.4 CDJ69645.1 - 3.6 5.6 51.0 5 5.2 35.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDJ69645.1 - 9.6 6.4 25.1 3.4 7.9 9.0 2.2 2 0 0 2 2 2 0 AAA domain Sporozoite_P67 PF05642.6 CDJ69646.1 - 0.001 17.0 0.9 0.0015 16.4 0.6 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Ion_trans PF00520.26 CDJ69647.1 - 0.012 14.9 16.1 0.091 12.0 5.8 2.2 1 1 1 2 2 2 0 Ion transport protein Methyltransf_3 PF01596.12 CDJ69648.1 - 2.6e-22 78.9 0.0 1.6e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase Rhodanese PF00581.15 CDJ69648.1 - 3.4e-11 43.5 0.0 7.9e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_24 PF13578.1 CDJ69648.1 - 9.9e-09 35.9 0.0 3.7e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ69648.1 - 0.00051 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ69648.1 - 0.015 15.3 0.0 0.056 13.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain tRNA_Me_trans PF03054.11 CDJ69649.1 - 8.7e-78 261.3 0.0 1.2e-70 237.8 0.0 2.4 2 0 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.16 CDJ69649.1 - 0.0096 15.4 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase SufE PF02657.10 CDJ69649.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Fe-S metabolism associated domain ThiI PF02568.9 CDJ69649.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Rep_fac-A_3 PF08661.6 CDJ69650.1 - 1.5e-11 44.1 0.0 1.5e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 SET PF00856.23 CDJ69651.1 - 0.0093 16.2 0.7 0.25 11.6 0.0 2.9 2 0 0 2 2 2 1 SET domain Hid1 PF12722.2 CDJ69651.1 - 6.2 4.3 9.2 9.8 3.7 6.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDJ69651.1 - 8.3 3.9 11.3 14 3.2 7.8 1.2 1 0 0 1 1 1 0 Ycf1 Carb_anhydrase PF00194.16 CDJ69652.1 - 8.2e-12 44.6 2.8 1.1e-09 37.6 0.1 3.0 3 0 0 3 3 3 2 Eukaryotic-type carbonic anhydrase DUF387 PF04079.11 CDJ69652.1 - 0.098 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) MFS_1 PF07690.11 CDJ69653.1 - 1.6e-11 43.5 21.8 3.5e-09 35.8 15.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ycf1 PF05758.7 CDJ69653.1 - 0.15 9.7 0.0 0.23 9.1 0.0 1.2 1 0 0 1 1 1 0 Ycf1 TPR_11 PF13414.1 CDJ69655.1 - 5.4e-10 38.7 0.0 1.4e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CDJ69655.1 - 4.1e-09 35.6 0.1 7.4e-07 28.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat GFO_IDH_MocA PF01408.17 CDJ69655.1 - 1.9e-07 31.6 0.0 4.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_2 PF07719.12 CDJ69655.1 - 5.1e-07 29.1 0.0 0.001 18.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDJ69655.1 - 2.8e-05 23.9 0.0 9.7e-05 22.2 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ69655.1 - 6.6e-05 22.4 0.0 0.022 14.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ69655.1 - 0.0024 17.5 0.0 0.96 9.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDJ69655.1 - 0.0027 18.1 0.0 1.1 10.1 0.0 3.4 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ69655.1 - 0.015 15.9 0.0 0.059 14.0 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ69655.1 - 0.021 14.9 0.0 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDJ69655.1 - 0.065 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Methyltransf_28 PF02636.12 CDJ69655.1 - 0.19 11.0 0.0 0.45 9.8 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SNARE PF05739.14 CDJ69656.1 - 0.0049 16.5 1.6 0.0049 16.5 1.1 2.7 4 1 0 4 4 4 1 SNARE domain tRNA-synt_2d PF01409.15 CDJ69656.1 - 0.18 10.9 2.2 1.8 7.7 0.5 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) AAA_11 PF13086.1 CDJ69659.1 - 6e-50 170.0 3.9 6e-50 170.0 2.7 6.3 6 1 0 6 6 6 1 AAA domain AAA_12 PF13087.1 CDJ69659.1 - 5e-33 114.1 0.0 1.4e-32 112.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CDJ69659.1 - 7.4e-28 97.3 13.9 2.1e-25 89.3 0.3 4.2 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CDJ69659.1 - 1e-14 54.6 0.3 1e-14 54.6 0.2 6.8 9 0 0 9 9 7 1 Signal recognition particle, alpha subunit, N-terminal AAA_19 PF13245.1 CDJ69659.1 - 6.1e-11 41.9 0.2 6.1e-11 41.9 0.1 8.6 8 2 0 8 8 4 1 Part of AAA domain R3H PF01424.17 CDJ69659.1 - 1.3e-09 37.5 0.1 1.3e-09 37.5 0.1 2.2 2 0 0 2 2 1 1 R3H domain zf-AN1 PF01428.11 CDJ69659.1 - 1.2e-07 31.5 7.6 2.3e-07 30.5 5.2 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger AAA_22 PF13401.1 CDJ69659.1 - 2.3e-06 27.7 7.1 0.018 15.1 0.0 5.7 3 2 1 4 4 4 2 AAA domain AAA PF00004.24 CDJ69659.1 - 0.00039 20.6 1.0 0.085 13.0 0.0 4.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CDJ69659.1 - 0.0028 17.3 0.3 11 5.6 0.0 3.9 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Zot PF05707.7 CDJ69659.1 - 0.0059 16.0 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) CbiA PF01656.18 CDJ69659.1 - 0.0095 15.3 3.2 1.7 7.9 0.6 3.8 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 CDJ69659.1 - 0.036 14.8 0.5 1.4 9.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CDJ69659.1 - 0.046 13.1 2.6 0.97 8.8 0.0 3.4 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 CDJ69659.1 - 0.15 12.2 0.3 9.1 6.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 CDJ69659.1 - 0.19 11.3 0.4 1.3e+02 2.2 0.0 3.7 4 0 0 4 4 4 0 NTPase AAA_18 PF13238.1 CDJ69659.1 - 0.26 11.6 1.1 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 CDJ69659.1 - 0.6 9.1 0.0 1.4 7.9 0.0 1.5 1 0 0 1 1 1 0 KaiC V_ATPase_I PF01496.14 CDJ69659.1 - 4.4 5.0 1.2 11 3.7 0.9 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ssl1 PF04056.9 CDJ69660.1 - 6.4e-31 107.4 0.0 1.4e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like 60KD_IMP PF02096.15 CDJ69660.1 - 0.0011 18.6 3.8 0.0016 18.1 2.6 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein BRF1 PF07741.8 CDJ69660.1 - 0.0025 17.9 1.3 0.0081 16.3 0.9 2.0 1 0 0 1 1 1 1 Brf1-like TBP-binding domain zf-DHHC PF01529.15 CDJ69660.1 - 0.0034 16.8 1.4 0.0045 16.4 1.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1644 PF07800.7 CDJ69660.1 - 0.004 17.0 5.4 0.004 17.0 3.8 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF1644) Suf PF05843.9 CDJ69660.1 - 0.0055 16.4 9.3 0.0072 16.0 6.4 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) SAGA-Tad1 PF12767.2 CDJ69660.1 - 0.0061 16.2 8.8 0.01 15.5 6.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit AUX_IAA PF02309.11 CDJ69660.1 - 0.0069 16.1 3.2 0.01 15.6 2.2 1.2 1 0 0 1 1 1 1 AUX/IAA family PAT1 PF09770.4 CDJ69660.1 - 0.01 14.1 26.5 0.013 13.7 18.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Baculo_PP31 PF05311.6 CDJ69660.1 - 0.017 14.4 5.5 0.025 13.8 3.8 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Band_3_cyto PF07565.8 CDJ69660.1 - 0.021 14.3 5.3 0.03 13.8 3.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peroxin-13_N PF04088.8 CDJ69660.1 - 0.022 14.7 1.8 0.041 13.8 1.2 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region AAA_23 PF13476.1 CDJ69660.1 - 0.041 14.2 10.3 0.056 13.7 7.1 1.2 1 0 0 1 1 1 0 AAA domain DUF2203 PF09969.4 CDJ69660.1 - 0.087 13.0 5.5 0.26 11.5 3.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Neur_chan_memb PF02932.11 CDJ69660.1 - 0.09 12.6 0.3 0.1 12.4 0.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CRF1 PF10380.4 CDJ69660.1 - 0.11 12.8 2.0 0.16 12.2 1.4 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 RR_TM4-6 PF06459.7 CDJ69660.1 - 0.17 11.7 5.9 0.25 11.2 4.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDJ69660.1 - 0.18 9.4 5.8 0.21 9.2 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHHW PF14286.1 CDJ69660.1 - 0.19 11.0 4.9 0.26 10.5 3.4 1.1 1 0 0 1 1 1 0 DHHW protein EIIBC-GUT_N PF03612.9 CDJ69660.1 - 0.29 10.7 5.4 0.48 10.0 3.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DDHD PF02862.12 CDJ69660.1 - 0.76 9.5 7.1 1.2 8.9 4.9 1.2 1 0 0 1 1 1 0 DDHD domain Gag_spuma PF03276.9 CDJ69660.1 - 0.83 7.9 25.3 1.7 6.9 17.5 1.4 1 0 0 1 1 1 0 Spumavirus gag protein DUF4557 PF15101.1 CDJ69660.1 - 0.85 9.4 21.3 1.4 8.7 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Activator_LAG-3 PF11498.3 CDJ69660.1 - 0.86 8.2 44.9 1.2 7.7 31.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ycf1 PF05758.7 CDJ69660.1 - 0.91 7.1 7.8 1.2 6.7 5.4 1.1 1 0 0 1 1 1 0 Ycf1 Pex16 PF08610.5 CDJ69660.1 - 1.8 7.5 7.9 2.5 6.9 5.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Serinc PF03348.10 CDJ69660.1 - 2.9 6.5 9.7 5.8 5.5 6.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) RNA_pol_Rbc25 PF08292.7 CDJ69660.1 - 3.6 7.8 8.8 6.1 7.0 6.1 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Peptidase_S49_N PF08496.5 CDJ69660.1 - 6 6.6 11.3 12 5.6 7.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_transf_15 PF01793.11 CDJ69660.1 - 6.9 5.5 10.1 9.7 5.0 7.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF912 PF06024.7 CDJ69660.1 - 8.6 6.4 8.2 17 5.5 5.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ctr PF04145.10 CDJ69661.1 - 5.2 7.1 7.6 0.47 10.4 0.1 2.2 2 0 0 2 2 2 0 Ctr copper transporter family F-protein PF00469.15 CDJ69662.1 - 6.9 5.9 14.9 7.6 5.8 10.3 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF4175 PF13779.1 CDJ69663.1 - 0.76 7.4 53.9 0.96 7.0 37.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CDJ69663.1 - 1.8 6.6 68.0 2 6.5 47.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Frizzled PF01534.12 CDJ69663.1 - 3 6.5 4.7 4.1 6.0 3.3 1.3 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF4366 PF14283.1 CDJ69663.1 - 4.1 6.7 15.0 4.7 6.5 9.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Helicase_C_2 PF13307.1 CDJ69664.1 - 2.7e-40 138.0 0.0 3.1e-39 134.5 0.0 2.7 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CDJ69664.1 - 1.4e-29 102.6 1.7 3.2e-29 101.5 0.0 2.2 2 0 0 2 2 2 1 DEAD_2 SseC PF04888.7 CDJ69665.1 - 0.00056 19.3 0.5 0.00069 19.0 0.4 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family MFS_1 PF07690.11 CDJ69665.1 - 0.0031 16.3 4.8 0.0035 16.0 3.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CbtA PF09490.5 CDJ69665.1 - 0.0049 16.1 1.1 0.0074 15.6 0.8 1.3 1 1 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) Med15 PF09606.5 CDJ69665.1 - 0.0086 14.3 8.0 0.0087 14.3 5.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3681 PF12442.3 CDJ69665.1 - 0.047 13.8 2.2 0.075 13.2 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) DHquinase_II PF01220.14 CDJ69665.1 - 0.087 12.1 0.1 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Dehydroquinase class II DivIC PF04977.10 CDJ69665.1 - 0.098 12.1 8.9 0.15 11.5 6.2 1.2 1 0 0 1 1 1 0 Septum formation initiator NPH3 PF03000.9 CDJ69665.1 - 0.099 12.1 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 NPH3 family RAB3GAP2_N PF14655.1 CDJ69665.1 - 0.38 9.6 5.3 0.5 9.2 3.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BAF1_ABF1 PF04684.8 CDJ69665.1 - 0.41 9.4 7.0 0.48 9.2 4.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PHD_3 PF13922.1 CDJ69665.1 - 0.68 10.2 4.5 1.3 9.2 3.1 1.5 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx ATG22 PF11700.3 CDJ69665.1 - 0.68 8.3 9.1 0.29 9.5 0.5 2.0 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like E_Pc_C PF06752.7 CDJ69665.1 - 0.68 9.3 7.5 0.88 9.0 5.2 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF4175 PF13779.1 CDJ69665.1 - 0.96 7.0 11.9 1.5 6.4 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TSA PF03249.8 CDJ69665.1 - 7.3 4.9 11.8 9.5 4.6 8.1 1.1 1 0 0 1 1 1 0 Type specific antigen RNA_pol_Rbc25 PF08292.7 CDJ69666.1 - 3.6e-24 85.2 0.1 4.4e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CDJ69666.1 - 2.3e-11 43.6 0.0 4.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Ribosomal_60s PF00428.14 CDJ69666.1 - 0.0067 16.8 12.1 0.013 15.8 8.4 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein S1 PF00575.18 CDJ69666.1 - 0.021 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 S1 RNA binding domain DUF755 PF05501.6 CDJ69667.1 - 0.0017 18.4 31.0 0.0017 18.4 21.5 5.8 5 1 1 6 6 6 2 Domain of unknown function (DUF755) GTP_EFTU PF00009.22 CDJ69668.1 - 2.2e-27 95.7 0.0 4.2e-18 65.4 0.2 3.8 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CDJ69668.1 - 2.7e-06 27.1 0.0 6.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CDJ69668.1 - 0.00011 22.0 0.0 0.00029 20.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus SR-25 PF10500.4 CDJ69668.1 - 0.002 17.6 4.0 0.002 17.6 2.8 6.7 7 0 0 7 7 7 1 Nuclear RNA-splicing-associated protein CD20 PF04103.10 CDJ69668.1 - 0.028 14.3 7.3 0.16 11.8 0.1 3.5 3 0 0 3 3 3 0 CD20-like family Spt20 PF12090.3 CDJ69668.1 - 0.056 12.7 17.5 0.045 13.0 2.0 3.8 4 0 0 4 4 4 0 Spt20 family Tmemb_9 PF05434.6 CDJ69668.1 - 0.091 12.5 0.0 0.091 12.5 0.0 3.6 4 0 0 4 4 4 0 TMEM9 Rer1 PF03248.8 CDJ69668.1 - 0.37 10.3 0.0 0.98 8.9 0.0 1.6 2 0 0 2 2 2 0 Rer1 family Neur_chan_memb PF02932.11 CDJ69668.1 - 1.7 8.4 7.9 9.4 6.0 0.0 3.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EphA2_TM PF14575.1 CDJ69668.1 - 6.8 7.1 6.5 3.4 8.1 0.1 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Actin PF00022.14 CDJ69669.1 - 1.5e-21 76.3 0.0 2.1e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Actin Med15 PF09606.5 CDJ69669.1 - 0.001 17.3 17.7 0.001 17.3 12.3 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDJ69669.1 - 0.0027 15.5 7.6 0.0035 15.1 1.5 2.0 2 0 0 2 2 2 1 Ycf1 Pex14_N PF04695.8 CDJ69669.1 - 0.0028 17.7 1.1 0.0028 17.7 0.8 3.6 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2201_N PF13203.1 CDJ69669.1 - 0.01 15.0 7.9 0.01 15.0 5.5 2.2 2 0 0 2 2 2 1 Putative metallopeptidase domain GAGA_bind PF06217.7 CDJ69669.1 - 0.015 15.2 3.1 0.015 15.2 2.2 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family zf-DHHC PF01529.15 CDJ69669.1 - 0.036 13.4 2.3 0.34 10.2 0.4 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase MreB_Mbl PF06723.8 CDJ69669.1 - 0.075 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Gti1_Pac2 PF09729.4 CDJ69669.1 - 0.078 12.8 0.2 0.078 12.8 0.2 2.5 2 1 0 2 2 1 0 Gti1/Pac2 family Spt20 PF12090.3 CDJ69669.1 - 0.21 10.8 18.3 0.48 9.7 5.3 2.5 2 0 0 2 2 2 0 Spt20 family IncA PF04156.9 CDJ69669.1 - 0.4 10.2 28.5 0.45 10.0 8.4 2.4 2 0 0 2 2 2 0 IncA protein RR_TM4-6 PF06459.7 CDJ69669.1 - 0.63 9.8 22.3 0.81 9.5 7.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 GvpL_GvpF PF06386.6 CDJ69669.1 - 1.1 8.7 23.1 0.027 14.0 5.6 2.4 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Tom37_C PF11801.3 CDJ69669.1 - 1.3 8.8 20.1 0.21 11.4 5.2 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain Adaptin_binding PF10199.4 CDJ69669.1 - 1.6 9.0 22.6 0.89 9.8 0.7 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TFIIA PF03153.8 CDJ69669.1 - 1.9 8.3 38.2 2 8.2 10.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Anoctamin PF04547.7 CDJ69669.1 - 1.9 7.0 7.8 2.6 6.5 3.5 1.9 2 0 0 2 2 2 0 Calcium-activated chloride channel ARGLU PF15346.1 CDJ69669.1 - 2 8.1 35.1 1.6 8.4 5.3 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 SAGA-Tad1 PF12767.2 CDJ69669.1 - 2 7.9 26.7 0.58 9.7 4.2 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Spore_coat_CotO PF14153.1 CDJ69669.1 - 3.1 7.1 33.2 0.96 8.8 11.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO PH_4 PF15404.1 CDJ69669.1 - 3.3 7.2 18.2 0.15 11.6 4.3 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Zip PF02535.17 CDJ69669.1 - 4 6.3 6.4 4.9 6.0 0.9 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Pex16 PF08610.5 CDJ69669.1 - 4.2 6.2 20.7 1.4 7.8 3.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) GPCR_chapero_1 PF11904.3 CDJ69669.1 - 4.7 6.2 19.7 1.7 7.7 2.8 2.1 2 0 0 2 2 2 0 GPCR-chaperone Suf PF05843.9 CDJ69669.1 - 4.9 6.7 28.6 0.39 10.3 5.5 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1764 PF08576.5 CDJ69669.1 - 5.6 7.8 26.3 0.56 11.0 6.4 2.7 3 0 0 3 3 2 0 Eukaryotic protein of unknown function (DUF1764) MRP-S26 PF14943.1 CDJ69669.1 - 5.7 6.4 22.8 0.22 11.0 7.7 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 PAT1 PF09770.4 CDJ69669.1 - 7.8 4.6 46.9 1.2 7.3 12.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Vfa1 PF08432.5 CDJ69669.1 - 10 6.1 25.0 2.7 7.9 7.8 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 CDJ69670.1 - 7.3 6.2 10.6 0.32 10.6 0.1 3.5 3 1 0 3 3 3 0 FAM176 family zf-Apc11 PF12861.2 CDJ69671.1 - 2.6e-21 75.2 6.3 3.6e-21 74.8 4.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CDJ69671.1 - 2.7e-21 75.4 5.6 3.9e-21 74.9 3.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CDJ69671.1 - 4.7e-09 35.9 8.2 1.5e-08 34.3 5.7 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CDJ69671.1 - 5.6e-07 29.1 5.0 1.4e-06 27.9 3.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDJ69671.1 - 5.2e-05 22.8 1.1 0.00011 21.7 0.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ69671.1 - 0.0001 22.2 6.1 0.0012 18.7 4.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDJ69671.1 - 0.00042 19.9 5.7 0.002 17.7 3.0 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CDJ69671.1 - 0.061 12.8 2.6 0.1 12.1 1.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.13 CDJ69671.1 - 0.6 9.2 0.0 0.6 9.2 0.0 2.6 2 1 1 3 3 3 0 Zn-finger in Ran binding protein and others RINGv PF12906.2 CDJ69671.1 - 6.9 6.8 9.6 1.2e+02 2.7 6.7 2.5 1 1 1 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.1 CDJ69671.1 - 9.8 6.1 11.0 0.19 11.6 1.0 2.8 2 2 0 2 2 2 0 zinc finger of C3HC4-type, RING Neur_chan_memb PF02932.11 CDJ69672.1 - 7.1 6.4 9.4 4.5 7.1 4.8 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF605 PF04652.11 CDJ69672.1 - 9 5.5 43.4 0.23 10.8 20.4 2.2 2 0 0 2 2 2 0 Vta1 like Macoilin PF09726.4 CDJ69674.1 - 0.92 7.7 21.0 1.1 7.4 14.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4647 PF15504.1 CDJ69674.1 - 2.3 6.9 12.0 2.8 6.6 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF755 PF05501.6 CDJ69674.1 - 10 6.2 36.1 10 6.2 20.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Macoilin PF09726.4 CDJ69675.1 - 4.7e-07 28.4 10.7 4.7e-07 28.4 7.4 4.4 2 1 1 3 3 3 1 Transmembrane protein OmpH PF03938.9 CDJ69675.1 - 0.0057 16.6 10.0 0.0057 16.6 6.9 8.7 6 3 2 8 8 8 3 Outer membrane protein (OmpH-like) MRP-S26 PF14943.1 CDJ69676.1 - 2.4 7.6 11.6 3.7 7.0 8.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 MLIP PF15274.1 CDJ69677.1 - 5.3 6.4 12.4 6.1 6.2 8.6 1.1 1 0 0 1 1 1 0 Muscular LMNA-interacting protein DUF702 PF05142.7 CDJ69677.1 - 8.4 6.5 17.1 12 6.0 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Biotin_lipoyl_2 PF13533.1 CDJ69678.1 - 0.035 13.7 0.0 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like RBFA PF02033.13 CDJ69679.1 - 1.7e-10 40.8 0.0 3.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A UDPGP PF01704.13 CDJ69681.1 - 8.4e-09 34.4 0.0 1.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase SR-25 PF10500.4 CDJ69681.1 - 0.54 9.6 13.2 0.67 9.3 7.3 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CoA_binding PF02629.14 CDJ69683.1 - 9.3e-24 83.7 0.0 1.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.1 CDJ69683.1 - 1.5e-05 25.1 0.1 2.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 CoA binding domain CDK2AP PF09806.4 CDJ69683.1 - 0.00033 20.9 7.7 0.00033 20.9 5.3 2.1 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein GFO_IDH_MocA PF01408.17 CDJ69683.1 - 0.0099 16.3 0.0 0.029 14.8 0.0 1.8 1 1 1 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Phostensin_N PF13916.1 CDJ69683.1 - 0.037 14.0 12.8 0.69 9.9 0.6 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Presenilin PF01080.12 CDJ69683.1 - 0.074 11.8 8.5 0.12 11.2 5.9 1.2 1 0 0 1 1 1 0 Presenilin GspL_C PF12693.2 CDJ69683.1 - 0.17 11.6 14.1 0.067 12.9 1.9 2.2 2 0 0 2 2 2 0 GspL periplasmic domain Plasmodium_Vir PF05795.6 CDJ69683.1 - 0.26 10.4 2.8 0.36 9.9 1.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.1 CDJ69683.1 - 0.73 9.5 7.5 1.2 8.8 4.2 1.8 2 0 0 2 2 2 0 Protein Family FAM60A DUF3740 PF12548.3 CDJ69683.1 - 1.4 9.1 10.9 2.1 8.6 5.6 2.4 2 1 0 2 2 2 0 Sulfatase protein PAT1 PF09770.4 CDJ69683.1 - 2.7 6.1 19.1 1.8 6.6 8.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 NPR3 PF03666.8 CDJ69683.1 - 4.3 5.7 9.8 8.1 4.8 6.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.2 CDJ69683.1 - 4.4 4.8 9.4 6.7 4.2 6.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM70 PF14967.1 CDJ69683.1 - 4.4 6.3 10.4 7.1 5.7 7.2 1.2 1 0 0 1 1 1 0 FAM70 protein Golgin_A5 PF09787.4 CDJ69683.1 - 5.2 5.4 17.9 2 6.8 9.7 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF2217 PF10265.4 CDJ69683.1 - 7.3 5.2 12.7 9.8 4.8 8.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Med15 PF09606.5 CDJ69684.1 - 0.83 7.7 10.0 0.96 7.5 6.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SWI-SNF_Ssr4 PF08549.5 CDJ69684.1 - 2.2 6.5 13.6 2.3 6.4 9.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) CT47 PF15623.1 CDJ69684.1 - 8.3 6.0 24.6 10 5.7 17.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Receptor_IA-2 PF11548.3 CDJ69685.1 - 0.22 11.4 1.2 0.28 11.1 0.5 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 DUF1212 PF06738.7 CDJ69685.1 - 0.43 10.0 5.0 0.47 9.8 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF2232 PF09991.4 CDJ69685.1 - 0.44 9.4 1.8 0.5 9.3 1.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Med15 PF09606.5 CDJ69685.1 - 0.64 8.1 19.8 0.67 8.0 13.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3708 PF12501.3 CDJ69685.1 - 1.1 9.0 15.5 1.5 8.6 10.8 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter R_equi_Vir PF05526.6 CDJ69685.1 - 4 7.0 11.4 4.7 6.8 7.9 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein MDMPI_N PF11716.3 CDJ69685.1 - 4 7.8 23.3 4.5 7.6 16.2 1.0 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain TauE PF01925.14 CDJ69685.1 - 4.2 6.7 8.8 5.6 6.3 6.1 1.2 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF3054 PF11255.3 CDJ69685.1 - 8.2 6.3 10.9 5.1 6.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3054) Macoilin PF09726.4 CDJ69686.1 - 0.00073 17.9 0.9 0.00079 17.8 0.7 1.0 1 0 0 1 1 1 1 Transmembrane protein Lipoprotein_2 PF00921.12 CDJ69686.1 - 0.27 11.2 19.3 0.23 11.4 11.5 1.9 2 0 0 2 2 2 0 Borrelia lipoprotein PAT1 PF09770.4 CDJ69686.1 - 0.28 9.3 18.9 0.3 9.2 13.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ69686.1 - 0.47 8.5 30.5 0.64 8.1 21.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.12 CDJ69686.1 - 1.4 7.7 3.8 1.7 7.4 2.6 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.8 CDJ69686.1 - 1.4 8.6 20.9 1.8 8.3 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 CDJ69686.1 - 9.6 5.0 16.0 0.031 13.2 1.6 2.0 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDJ69687.1 - 6.4 5.7 32.3 2.1 7.3 6.2 3.0 3 0 0 3 3 3 0 Fms-interacting protein UPF0016 PF01169.14 CDJ69688.1 - 4.3e-08 33.1 13.2 1.9e-07 31.0 9.2 2.0 1 1 0 1 1 1 1 Uncharacterized protein family UPF0016 PrgH PF09480.5 CDJ69689.1 - 0.014 14.2 1.4 0.016 14.0 1.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) DUF2345 PF10106.4 CDJ69689.1 - 0.074 12.6 5.4 0.088 12.4 1.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF164 PF02591.10 CDJ69689.1 - 2.8 7.8 7.7 0.31 10.9 1.3 2.4 2 1 1 3 3 3 0 Putative zinc ribbon domain Med15 PF09606.5 CDJ69690.1 - 1.8 6.6 25.6 2.3 6.2 17.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Stk19 PF10494.4 CDJ69692.1 - 0.0018 17.7 16.9 0.0051 16.2 11.7 1.7 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 GRIP PF01465.15 CDJ69693.1 - 1.9e-12 46.4 1.5 1e-11 44.1 1.1 2.4 1 0 0 1 1 1 1 GRIP domain Cob_adeno_trans PF01923.13 CDJ69694.1 - 0.014 15.2 0.1 0.014 15.2 0.1 3.0 3 1 0 3 3 3 0 Cobalamin adenosyltransferase RAB3GAP2_N PF14655.1 CDJ69694.1 - 3.1 6.7 33.7 0.24 10.3 0.3 4.2 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus EzrA PF06160.7 CDJ69695.1 - 0.013 13.7 1.0 0.02 13.1 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CAF-1_p150 PF11600.3 CDJ69696.1 - 0.0013 18.1 13.8 0.0013 18.1 9.6 2.7 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2371 PF10177.4 CDJ69696.1 - 4.8 7.0 7.6 49 3.7 5.3 2.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DEAD PF00270.24 CDJ69697.1 - 3.6e-31 107.9 3.8 2.3e-28 98.7 0.1 3.3 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ69697.1 - 0.0068 16.2 0.1 0.51 10.2 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SR-25 PF10500.4 CDJ69698.1 - 8.5e-05 22.1 18.9 8.5e-05 22.1 13.1 3.3 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein BUD22 PF09073.5 CDJ69698.1 - 0.0039 16.3 9.7 0.0054 15.8 6.7 1.2 1 0 0 1 1 1 1 BUD22 GPCR_chapero_1 PF11904.3 CDJ69698.1 - 0.21 10.7 4.6 0.3 10.1 3.2 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF4131 PF13567.1 CDJ69698.1 - 5.6 6.3 7.3 89 2.4 5.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) zf-C2H2_2 PF12756.2 CDJ69699.1 - 0.042 13.9 0.1 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3342 PF11822.3 CDJ69699.1 - 0.19 10.8 3.1 0.18 10.8 0.5 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3342) RNA_POL_M_15KD PF02150.11 CDJ69699.1 - 0.7 9.6 3.0 13 5.5 0.1 3.0 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Hist_deacetyl PF00850.14 CDJ69700.1 - 3.2e-69 233.5 0.0 2.5e-68 230.6 0.0 2.3 1 1 0 1 1 1 1 Histone deacetylase domain Chordopox_L2 PF05803.7 CDJ69700.1 - 0.19 11.3 0.2 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus L2 protein Herpes_UL17 PF04559.7 CDJ69700.1 - 9.7 4.6 9.5 17 3.8 6.6 1.4 1 0 0 1 1 1 0 Herpesvirus UL17 protein RAB3GAP2_N PF14655.1 CDJ69701.1 - 0.51 9.2 3.4 0.12 11.3 0.4 1.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DnaJ PF00226.26 CDJ69702.1 - 3.8e-26 90.5 0.3 7.1e-26 89.7 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain HemX PF04375.9 CDJ69703.1 - 0.0054 15.3 30.7 0.007 15.0 21.3 1.1 1 0 0 1 1 1 1 HemX Med15 PF09606.5 CDJ69703.1 - 0.0071 14.6 62.5 0.0084 14.3 43.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ69703.1 - 0.009 15.7 18.7 0.012 15.4 13.0 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DDHD PF02862.12 CDJ69703.1 - 0.22 11.3 17.2 0.26 11.0 11.9 1.1 1 0 0 1 1 1 0 DDHD domain FimP PF09766.4 CDJ69703.1 - 0.33 9.9 31.6 0.42 9.6 21.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein AvrE PF11725.3 CDJ69703.1 - 0.34 7.8 19.1 0.35 7.8 13.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor eIF-3_zeta PF05091.7 CDJ69703.1 - 0.36 9.3 21.4 0.41 9.2 14.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.17 CDJ69703.1 - 0.37 9.7 5.6 0.45 9.4 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 CDJ69703.1 - 0.39 9.5 19.0 0.47 9.2 13.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TFIIA PF03153.8 CDJ69703.1 - 0.63 9.8 36.4 0.9 9.3 25.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 CDJ69703.1 - 0.67 9.7 18.0 0.88 9.4 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 CDJ69703.1 - 0.7 8.4 12.2 0.97 7.9 8.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AUX_IAA PF02309.11 CDJ69703.1 - 0.78 9.4 17.1 1.1 8.9 11.9 1.2 1 0 0 1 1 1 0 AUX/IAA family PA26 PF04636.8 CDJ69703.1 - 0.79 8.3 11.8 0.96 8.0 8.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CPSF100_C PF13299.1 CDJ69703.1 - 0.8 9.8 14.1 1.2 9.3 9.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SAGA-Tad1 PF12767.2 CDJ69703.1 - 1 8.9 24.3 1.3 8.6 16.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1510 PF07423.6 CDJ69703.1 - 1.3 8.3 21.9 1.8 7.9 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PAT1 PF09770.4 CDJ69703.1 - 1.7 6.7 45.0 1.9 6.5 31.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.12 CDJ69703.1 - 2 7.1 14.2 2.4 6.9 9.8 1.1 1 0 0 1 1 1 0 Presenilin FHIPEP PF00771.15 CDJ69703.1 - 2.5 6.3 7.7 3.1 6.0 5.3 1.3 1 0 0 1 1 1 0 FHIPEP family Apt1 PF10351.4 CDJ69703.1 - 2.6 6.7 16.7 3.2 6.5 11.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2413 PF10310.4 CDJ69703.1 - 2.9 6.6 25.9 4 6.1 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) BTV_NS2 PF04514.7 CDJ69703.1 - 3.6 6.3 14.6 4.4 6.0 10.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Peptidase_S64 PF08192.6 CDJ69703.1 - 3.7 5.7 13.9 4.1 5.6 9.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Borrelia_P83 PF05262.6 CDJ69703.1 - 3.7 5.7 21.1 4.2 5.5 14.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Raftlin PF15250.1 CDJ69703.1 - 4 5.8 20.7 5 5.5 14.3 1.0 1 0 0 1 1 1 0 Raftlin DUF4544 PF15077.1 CDJ69703.1 - 4.4 6.7 10.2 5 6.5 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DUF2215 PF10225.4 CDJ69703.1 - 4.7 6.5 10.4 5.9 6.2 7.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Rtf2 PF04641.7 CDJ69703.1 - 5 6.2 20.8 7.1 5.7 14.4 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3450 PF11932.3 CDJ69703.1 - 5.2 6.2 30.7 7.5 5.7 21.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) OMP_b-brl PF13505.1 CDJ69703.1 - 5.7 6.8 12.6 8.3 6.3 8.7 1.5 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain Anoctamin PF04547.7 CDJ69703.1 - 6.5 5.2 7.8 7 5.1 5.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel GOLD_2 PF13897.1 CDJ69703.1 - 8.8 6.5 8.8 15 5.8 6.1 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Paramyxo_ncap PF00973.14 CDJ69703.1 - 9 4.8 17.5 10 4.6 12.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SelP_N PF04592.9 CDJ69703.1 - 9.3 5.5 17.5 12 5.1 12.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.11 CDJ69703.1 - 10 5.9 13.9 13 5.5 9.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Thiolase_N PF00108.18 CDJ69704.1 - 2.8e-70 236.3 0.1 3.5e-70 236.0 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 CDJ69704.1 - 6.8e-06 25.7 0.9 6.8e-06 25.7 0.7 2.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain P16-Arc PF04699.9 CDJ69704.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2360 PF10152.4 CDJ69705.1 - 0.18 12.0 2.3 0.27 11.5 1.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Med15 PF09606.5 CDJ69706.1 - 0.0011 17.3 41.6 0.0028 15.9 20.2 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ69706.1 - 2.7 6.1 44.2 0.95 7.6 21.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PFK PF00365.15 CDJ69707.1 - 1.5e-21 76.5 0.5 2.6e-20 72.5 0.1 2.8 3 0 0 3 3 3 1 Phosphofructokinase Methyltransf_2 PF00891.13 CDJ69707.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase zf-CCCH PF00642.19 CDJ69708.1 - 2.9e-13 49.1 17.2 0.00012 21.6 0.4 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF59 PF01883.14 CDJ69709.1 - 0.033 14.1 0.1 7.7 6.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF59 CytochromB561_N PF09786.4 CDJ69711.1 - 3.7 5.8 14.0 4.3 5.6 9.7 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF966 PF06136.8 CDJ69711.1 - 5.4 6.3 11.0 6.8 6.0 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.2 CDJ69711.1 - 8.5 3.9 10.4 10 3.6 7.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CRM1_C PF08767.6 CDJ69712.1 - 2.6e-96 322.2 0.3 2.9e-96 322.1 0.2 1.0 1 0 0 1 1 1 1 CRM1 C terminal Ribosomal_60s PF00428.14 CDJ69712.1 - 0.022 15.1 2.6 0.048 14.0 1.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.3 CDJ69713.1 - 0.12 11.7 5.8 0.19 11.0 4.0 1.3 1 0 0 1 1 1 0 Spt20 family RED_N PF07808.8 CDJ69713.1 - 0.12 11.5 10.5 0.2 10.8 7.3 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region LIM_bind PF01803.11 CDJ69713.1 - 0.23 10.5 8.4 0.34 10.0 5.8 1.2 1 0 0 1 1 1 0 LIM-domain binding protein RdRP_3 PF00998.18 CDJ69713.1 - 0.37 9.2 2.7 0.54 8.6 1.9 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase DUF4557 PF15101.1 CDJ69713.1 - 1.8 8.3 12.6 2.8 7.7 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDJ69713.1 - 4.5 5.3 22.0 6.1 4.9 15.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TSA PF03249.8 CDJ69713.1 - 4.8 5.5 12.2 7.2 5.0 8.5 1.3 1 0 0 1 1 1 0 Type specific antigen Med15 PF09606.5 CDJ69713.1 - 8.3 4.4 29.8 11 4.0 20.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDJ69713.1 - 9.1 4.8 6.6 12 4.4 4.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DEAD PF00270.24 CDJ69714.1 - 5.2e-32 110.6 15.3 5.2e-32 110.6 10.6 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ69714.1 - 5.7e-21 74.1 0.0 5.7e-21 74.1 0.0 3.6 3 1 1 4 4 4 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CDJ69714.1 - 0.53 9.3 0.0 0.53 9.3 0.0 2.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AP2 PF00847.15 CDJ69715.1 - 0.0026 17.8 0.4 0.0026 17.8 0.3 4.3 6 0 0 6 6 6 1 AP2 domain AAA_23 PF13476.1 CDJ69715.1 - 0.03 14.6 37.1 0.22 11.8 7.4 2.3 2 0 0 2 2 2 0 AAA domain SOBP PF15279.1 CDJ69716.1 - 3.5 7.9 8.1 4.1 7.7 5.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.4 CDJ69717.1 - 1.1e-05 25.0 6.2 1.1e-05 25.0 4.3 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 CDJ69717.1 - 0.019 14.9 10.4 0.019 14.9 7.2 3.4 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.12 CDJ69717.1 - 2.7 7.7 13.4 0.83 9.4 1.7 2.2 2 0 0 2 2 2 0 DDHD domain Hydrolase PF00702.21 CDJ69718.1 - 8.1e-18 65.6 11.2 2e-08 34.9 0.5 2.9 2 2 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CDJ69718.1 - 2.3e-11 43.1 0.4 1.2e-10 40.8 0.1 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CDJ69718.1 - 4.4e-11 42.5 3.2 5.7e-11 42.2 0.0 2.8 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CDJ69718.1 - 1.1e-06 28.9 3.7 1.5e-05 25.2 2.6 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Shadoo PF14999.1 CDJ69718.1 - 0.012 15.4 1.9 0.012 15.4 1.3 3.4 2 1 0 2 2 1 0 Shadow of prion protein, neuroprotective SpoVR PF04293.8 CDJ69718.1 - 0.025 12.9 4.0 0.29 9.4 0.1 2.2 2 0 0 2 2 2 0 SpoVR like protein Spt20 PF12090.3 CDJ69718.1 - 0.042 13.1 4.6 0.14 11.5 0.9 2.2 2 0 0 2 2 2 0 Spt20 family Spc24 PF08286.6 CDJ69718.1 - 0.056 13.1 11.0 0.91 9.2 2.3 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 zf-DHHC PF01529.15 CDJ69718.1 - 0.12 11.7 0.6 1 8.7 0.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Tim54 PF11711.3 CDJ69718.1 - 0.18 10.4 10.7 0.43 9.1 0.3 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Suf PF05843.9 CDJ69718.1 - 0.25 11.0 7.2 0.14 11.8 1.5 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ69718.1 - 0.54 9.2 19.0 0.25 10.3 6.8 2.2 2 0 0 2 2 2 0 Fms-interacting protein RR_TM4-6 PF06459.7 CDJ69718.1 - 0.77 9.6 12.1 1.5 8.6 2.9 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDJ69718.1 - 2.5 7.5 18.2 3.5 7.0 3.9 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DUF1510 PF07423.6 CDJ69718.1 - 4.7 6.5 22.4 6.6 6.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SR-25 PF10500.4 CDJ69718.1 - 7.2 6.0 29.5 0.67 9.3 1.7 3.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PV-1 PF06637.6 CDJ69719.1 - 1.3 7.4 3.0 1.6 7.2 2.1 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CD20 PF04103.10 CDJ69721.1 - 4.1 7.3 6.3 0.29 11.0 0.5 1.9 2 0 0 2 2 2 0 CD20-like family Glyco_transf_20 PF00982.16 CDJ69722.1 - 7.1e-56 189.6 1.7 9e-56 189.2 0.0 1.8 2 0 0 2 2 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CDJ69722.1 - 7.9e-38 129.6 0.0 8.6e-37 126.2 0.0 2.3 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 CDJ69722.1 - 0.0001 21.9 0.3 0.0007 19.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PAT1 PF09770.4 CDJ69722.1 - 0.05 11.8 20.4 0.072 11.3 14.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt5_N PF11942.3 CDJ69722.1 - 0.61 10.7 17.3 1.2 9.8 11.5 1.8 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal RR_TM4-6 PF06459.7 CDJ69722.1 - 1.3 8.8 11.0 2.5 7.9 7.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 CDJ69722.1 - 2.8 5.8 13.9 4 5.3 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDJ69722.1 - 5.3 4.6 11.9 7.2 4.1 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.1 CDJ69722.1 - 5.4 5.0 5.2 7.6 4.5 3.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Med15 PF09606.5 CDJ69722.1 - 7.3 4.6 36.4 10 4.1 25.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDJ69722.1 - 9.7 6.4 13.8 17 5.6 9.6 1.3 1 0 0 1 1 1 0 AAA domain TraT PF05818.7 CDJ69723.1 - 0.0059 16.0 5.0 0.0059 16.0 3.4 9.3 9 1 0 10 10 10 1 Enterobacterial TraT complement resistance protein Virul_fac_BrkB PF03631.10 CDJ69724.1 - 0.033 13.5 0.1 0.033 13.5 0.1 1.9 2 1 0 2 2 2 0 Virulence factor BrkB EI24 PF07264.6 CDJ69724.1 - 0.079 12.3 3.1 0.091 12.1 0.1 2.0 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Pex14_N PF04695.8 CDJ69724.1 - 0.089 12.8 2.5 3.5 7.6 0.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PNRC PF15365.1 CDJ69724.1 - 1.1 9.2 5.9 0.54 10.3 0.1 2.5 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Thymidylat_synt PF00303.14 CDJ69725.1 - 8.8e-30 103.6 0.0 1.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 CDJ69725.1 - 5.5e-28 97.5 0.1 2.1e-10 40.4 0.0 3.7 4 0 0 4 4 4 3 Dihydrofolate reductase DUF2722 PF10846.3 CDJ69725.1 - 0.042 12.8 6.4 0.2 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) AAA_23 PF13476.1 CDJ69725.1 - 0.14 12.4 6.5 0.25 11.6 4.5 1.4 1 0 0 1 1 1 0 AAA domain Anoctamin PF04547.7 CDJ69725.1 - 0.59 8.7 2.8 0.86 8.1 2.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF4557 PF15101.1 CDJ69725.1 - 6.7 6.4 13.4 3.1 7.5 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) FimP PF09766.4 CDJ69725.1 - 8.6 5.3 16.3 1.8 7.5 2.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein RRM_1 PF00076.17 CDJ69726.1 - 8.5e-08 31.7 0.0 1.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ69726.1 - 9.7e-05 22.2 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.14 CDJ69726.1 - 0.042 14.2 13.9 0.3 11.5 5.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein EXOSC1 PF10447.4 CDJ69727.1 - 4.4e-14 52.1 0.0 6.6e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CDJ69727.1 - 5.3e-08 32.0 1.2 6.9e-08 31.6 0.1 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region RAP PF08373.5 CDJ69728.1 - 1.6e-11 43.8 0.0 3.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 RAP domain DUF2722 PF10846.3 CDJ69728.1 - 0.015 14.3 0.1 0.015 14.3 0.0 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF2722) Pex14_N PF04695.8 CDJ69728.1 - 4.6 7.2 31.9 0.022 14.8 3.0 3.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 CDJ69729.1 - 8.5e-37 126.6 0.0 1.8e-33 115.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69729.1 - 2.4e-35 121.8 0.0 3.9e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.12 CDJ69729.1 - 7.2e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CDJ69729.1 - 0.00015 21.8 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Med15 PF09606.5 CDJ69731.1 - 0.0038 15.5 76.2 0.0025 16.0 16.3 3.2 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 CDJ69731.1 - 1.2 9.0 5.5 58 3.4 0.0 2.6 3 1 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region FAD_binding_3 PF01494.14 CDJ69733.1 - 4.9e-22 78.4 4.5 2.6e-13 49.7 0.4 4.6 5 0 0 5 5 5 3 FAD binding domain DUF677 PF05055.7 CDJ69734.1 - 0.00057 18.6 2.9 0.00057 18.6 2.0 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF677) DNA_pol_viral_N PF00242.12 CDJ69734.1 - 7.1 5.5 6.2 7.7 5.4 4.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Trehalose_PPase PF02358.11 CDJ69737.1 - 7e-09 34.9 1.0 3e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Trehalose-phosphatase NAD_binding_1 PF00175.16 CDJ69738.1 - 1.5e-13 51.2 0.8 4e-08 33.7 0.6 2.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CDJ69738.1 - 1.2e-07 31.7 0.2 1.1e-06 28.6 0.0 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF2722 PF10846.3 CDJ69738.1 - 3.3e-05 23.1 4.1 0.094 11.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.3 CDJ69738.1 - 0.00036 19.9 5.7 0.11 11.8 1.7 2.2 2 0 0 2 2 2 2 Spt20 family Med15 PF09606.5 CDJ69738.1 - 0.0063 14.7 34.7 0.12 10.5 14.2 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal RNA_pol_Rpb1_3 PF04983.13 CDJ69738.1 - 0.031 14.0 0.5 0.052 13.2 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 DUF1338 PF07063.8 CDJ69738.1 - 0.12 11.4 5.0 0.023 13.7 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) Shisa PF13908.1 CDJ69738.1 - 0.94 9.6 10.4 0.17 12.0 0.6 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Suf PF05843.9 CDJ69738.1 - 1.6 8.3 19.4 0.46 10.1 5.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1764 PF08576.5 CDJ69738.1 - 1.9 9.3 11.1 0.61 10.8 1.6 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) G10 PF01125.12 CDJ69738.1 - 2 7.9 6.5 0.93 9.0 1.4 2.2 2 0 0 2 2 2 0 G10 protein RAB3GAP2_N PF14655.1 CDJ69738.1 - 2.5 7.0 17.9 1.9 7.3 4.6 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus OATP PF03137.15 CDJ69738.1 - 3.1 5.7 6.6 1.2 7.0 1.4 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pex16 PF08610.5 CDJ69738.1 - 3.3 6.6 11.4 7.4 5.4 3.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Pex14_N PF04695.8 CDJ69738.1 - 4.5 7.3 17.8 6.5 6.8 1.4 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.10 CDJ69738.1 - 5 7.1 5.2 24 4.9 0.8 2.4 2 0 0 2 2 2 0 Ctr copper transporter family NAD_kinase PF01513.16 CDJ69739.1 - 0.00014 20.7 0.1 0.13 11.0 0.0 2.5 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.19 CDJ69739.1 - 0.038 13.4 3.1 0.046 13.1 0.0 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Spore_coat_CotO PF14153.1 CDJ69739.1 - 0.13 11.6 31.6 0.25 10.7 9.5 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Ycf1 PF05758.7 CDJ69739.1 - 0.19 9.3 16.0 0.21 9.2 1.0 2.0 2 0 0 2 2 2 0 Ycf1 NARP1 PF12569.3 CDJ69739.1 - 9.1 4.8 29.0 0.02 13.6 5.2 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 ATP-synt PF00231.14 CDJ69740.1 - 5.9e-08 32.4 0.9 5.9e-08 32.4 0.6 2.0 1 1 1 2 2 1 1 ATP synthase DUF4094 PF13334.1 CDJ69740.1 - 0.0026 18.1 13.6 0.032 14.5 4.8 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4094) DUF1071 PF06378.6 CDJ69740.1 - 0.022 13.9 14.1 0.22 10.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1071) WES_acyltransf PF03007.11 CDJ69740.1 - 0.029 13.9 1.1 0.029 13.9 0.7 2.0 1 1 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Trp_oprn_chp PF09534.5 CDJ69740.1 - 0.074 12.6 1.6 0.11 12.1 1.1 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EIIBC-GUT_N PF03612.9 CDJ69740.1 - 0.12 12.0 15.3 0.17 11.4 0.3 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FimP PF09766.4 CDJ69740.1 - 0.53 9.3 29.5 1.3 8.0 1.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein Ctr PF04145.10 CDJ69740.1 - 0.82 9.7 13.8 0.084 12.9 3.1 2.1 1 1 1 2 2 2 0 Ctr copper transporter family CD20 PF04103.10 CDJ69740.1 - 0.93 9.4 6.8 1.5 8.7 1.7 2.1 2 0 0 2 2 2 0 CD20-like family AIF_C PF14721.1 CDJ69740.1 - 1.2 9.3 12.7 8.4 6.6 5.4 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Glt_symporter PF03616.9 CDJ69740.1 - 2.6 6.4 7.7 0.11 10.9 0.8 1.7 1 1 1 2 2 2 0 Sodium/glutamate symporter DUF2149 PF09919.4 CDJ69740.1 - 3.2 7.9 11.4 3 8.0 3.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DUF4512 PF14975.1 CDJ69740.1 - 3.2 8.6 15.2 52 4.7 10.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Presenilin PF01080.12 CDJ69740.1 - 4 6.1 7.1 4.8 5.8 4.9 1.1 1 0 0 1 1 1 0 Presenilin Jiraiya PF15038.1 CDJ69740.1 - 4.1 6.8 5.8 2.5 7.4 2.9 1.5 1 1 0 1 1 1 0 Jiraiya Neurensin PF14927.1 CDJ69740.1 - 5 6.5 6.6 7.8 5.8 1.6 2.5 2 1 0 2 2 2 0 Neurensin PUCC PF03209.10 CDJ69740.1 - 6.4 5.3 12.9 6.6 5.3 3.6 2.0 1 1 1 2 2 2 0 PUCC protein K_trans PF02705.11 CDJ69740.1 - 6.4 5.0 6.4 0.96 7.7 1.8 1.5 2 0 0 2 2 2 0 K+ potassium transporter DUF2140 PF09911.4 CDJ69740.1 - 6.7 5.8 12.4 7.4 5.7 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) PH_4 PF15404.1 CDJ69740.1 - 8 5.9 16.6 7.6 6.0 7.4 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Conotoxin PF02950.12 CDJ69740.1 - 9 7.1 17.6 1.1 10.1 0.4 2.4 2 1 0 2 2 2 0 Conotoxin Daxx PF03344.10 CDJ69741.1 - 0.0047 15.5 27.7 0.008 14.7 19.2 1.4 1 0 0 1 1 1 1 Daxx Family LMBR1 PF04791.11 CDJ69741.1 - 0.02 13.4 0.0 0.042 12.4 0.0 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Otopetrin PF03189.8 CDJ69741.1 - 0.097 11.6 3.7 0.16 10.9 2.5 1.4 1 0 0 1 1 1 0 Otopetrin CENP-T PF15511.1 CDJ69741.1 - 0.39 9.9 41.6 0.72 9.0 28.8 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 CDJ69741.1 - 3.9 5.3 31.7 8.5 4.2 22.0 1.5 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin PF00085.15 CDJ69742.1 - 1.9e-12 46.7 0.0 2.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 CDJ69742.1 - 0.0013 18.2 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CDJ69742.1 - 0.13 11.9 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 CDJ69742.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.1 CDJ69742.1 - 0.15 12.2 1.0 0.49 10.6 0.7 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain SNF2_N PF00176.18 CDJ69743.1 - 1.4e-16 60.1 0.0 6.3e-10 38.3 0.0 3.0 3 0 0 3 3 3 2 SNF2 family N-terminal domain CAF-1_p150 PF11600.3 CDJ69743.1 - 1.9 7.8 47.8 0.029 13.7 16.6 3.6 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3446 PF11928.3 CDJ69743.1 - 2.2 8.5 44.6 0.56 10.4 5.0 4.9 4 1 0 4 4 4 0 Domain of unknown function (DUF3446) PA26 PF04636.8 CDJ69743.1 - 7.4 5.1 13.4 2.1 6.9 0.2 2.2 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DUF2317 PF10079.4 CDJ69744.1 - 0.28 9.7 9.5 0.31 9.5 6.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Corona_nucleoca PF00937.13 CDJ69744.1 - 2.9 6.7 11.2 3.4 6.5 7.7 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Gastrin PF00918.12 CDJ69744.1 - 5.3 7.8 7.8 6.8 7.5 5.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family MDFI PF15316.1 CDJ69744.1 - 7.7 6.4 6.1 8.7 6.3 4.2 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF2217 PF10265.4 CDJ69745.1 - 8.5 5.0 16.7 11 4.6 11.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) AsmA PF05170.9 CDJ69746.1 - 0.038 12.6 0.1 0.049 12.2 0.1 1.1 1 0 0 1 1 1 0 AsmA family CRISPR_Cse2 PF09485.5 CDJ69746.1 - 0.53 10.3 5.1 0.76 9.8 3.1 1.8 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) RRM_6 PF14259.1 CDJ69747.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CDJ69747.1 - 0.032 13.9 0.1 0.095 12.4 0.0 1.8 1 1 0 1 1 1 0 Limkain b1 HEAT_EZ PF13513.1 CDJ69748.1 - 1.1e-06 28.9 0.5 1.1e-06 28.9 0.4 7.0 5 2 1 6 6 6 2 HEAT-like repeat HEAT PF02985.17 CDJ69748.1 - 9.8e-06 25.2 2.8 9e-05 22.2 0.1 3.8 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CDJ69748.1 - 0.0059 16.8 0.1 0.0059 16.8 0.0 4.3 3 1 1 4 4 4 3 HEAT repeats Pex14_N PF04695.8 CDJ69748.1 - 0.73 9.8 30.4 0.48 10.4 5.6 4.2 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Transglut_prok PF09017.5 CDJ69748.1 - 1.7 7.6 9.7 4.4 6.3 0.0 2.5 2 1 0 2 2 2 0 Microbial transglutaminase Neur_chan_memb PF02932.11 CDJ69748.1 - 2.7 7.8 10.1 0.71 9.7 3.0 2.6 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.17 CDJ69749.1 - 2.3e-11 43.1 0.0 4.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ69749.1 - 4.1e-08 33.0 0.5 6.8e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ69749.1 - 1.8e-07 30.8 0.0 3.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 CDJ69749.1 - 0.031 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) SR-25 PF10500.4 CDJ69749.1 - 0.13 11.6 4.0 0.19 11.1 2.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HemY_N PF07219.8 CDJ69749.1 - 3.1 7.3 13.7 9.3 5.8 9.5 1.8 1 1 0 1 1 1 0 HemY protein N-terminus DUF4131 PF13567.1 CDJ69749.1 - 3.9 6.8 8.6 6.5 6.1 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1117 PF06547.7 CDJ69751.1 - 0.0014 18.6 3.3 0.002 18.1 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1117) SR-25 PF10500.4 CDJ69751.1 - 0.0023 17.4 13.3 0.0028 17.1 9.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MRI PF15325.1 CDJ69751.1 - 0.086 13.8 1.6 0.096 13.6 1.1 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection TraG-D_C PF12696.2 CDJ69751.1 - 0.19 11.5 1.5 0.25 11.2 1.0 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF508 PF04370.7 CDJ69751.1 - 0.56 9.8 5.3 0.71 9.4 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF755 PF05501.6 CDJ69751.1 - 1.1 9.3 18.2 1.8 8.6 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AF-4 PF05110.8 CDJ69751.1 - 7.1 4.3 15.3 7.9 4.2 10.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.4 CDJ69752.1 - 0.00054 19.5 9.8 0.0006 19.3 6.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2780 PF11075.3 CDJ69752.1 - 0.032 14.2 1.9 0.042 13.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) CAF-1_p150 PF11600.3 CDJ69752.1 - 0.037 13.4 8.5 0.044 13.1 5.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pex14_N PF04695.8 CDJ69752.1 - 0.08 12.9 7.0 0.1 12.6 4.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2201_N PF13203.1 CDJ69752.1 - 0.18 10.9 7.7 0.21 10.7 5.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDK2AP PF09806.4 CDJ69752.1 - 0.23 11.6 9.1 0.27 11.4 6.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Paramyxo_C PF01692.13 CDJ69752.1 - 0.36 10.4 3.7 0.4 10.2 2.6 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c DUF2076 PF09849.4 CDJ69752.1 - 0.36 10.8 9.2 0.39 10.7 6.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Suf PF05843.9 CDJ69752.1 - 0.48 10.1 4.3 0.52 10.0 3.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BAT2_N PF07001.6 CDJ69752.1 - 0.56 10.5 11.1 0.69 10.2 7.7 1.1 1 0 0 1 1 1 0 BAT2 N-terminus FRG2 PF15315.1 CDJ69752.1 - 1.1 9.2 15.3 1.3 8.9 10.6 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF4106 PF13388.1 CDJ69752.1 - 7.9 5.3 9.5 8.2 5.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF3626 PF12294.3 CDJ69755.1 - 5.8e-07 28.8 0.1 0.00092 18.3 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3626) Pkinase PF00069.20 CDJ69756.1 - 1.2e-36 126.2 0.0 1.3e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69756.1 - 3.4e-16 59.1 0.0 4.2e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CDJ69756.1 - 0.039 12.7 0.4 0.072 11.8 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.18 CDJ69756.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family CCDC144C PF14915.1 CDJ69758.1 - 0.043 12.7 6.1 0.069 12.0 4.2 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Peptidase_M50 PF02163.17 CDJ69765.1 - 0.3 10.0 0.8 0.58 9.0 0.6 1.4 1 0 0 1 1 1 0 Peptidase family M50 IQ PF00612.22 CDJ69768.1 - 0.012 15.2 0.1 0.042 13.4 0.1 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ret_tiss PF10044.4 CDJ69768.1 - 0.094 13.2 0.6 1.5 9.4 0.0 2.8 2 1 1 3 3 3 0 Retinal tissue protein Imm35 PF15581.1 CDJ69768.1 - 0.11 12.4 1.1 0.39 10.7 0.1 2.4 2 1 0 2 2 2 0 Immunity protein 35 DUF1825 PF08855.5 CDJ69768.1 - 0.33 10.9 7.8 0.038 13.9 0.8 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF1825) Beta-Casp PF10996.3 CDJ69770.1 - 0.0013 18.6 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Tmemb_14 PF03647.8 CDJ69771.1 - 7.1e-05 23.1 2.8 7.1e-05 23.1 1.9 1.8 2 0 0 2 2 2 1 Transmembrane proteins 14C FAD-oxidase_C PF02913.14 CDJ69772.1 - 3.3e-38 131.4 0.0 7.1e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CDJ69772.1 - 3.1e-35 120.6 0.3 5.5e-35 119.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CDJ69772.1 - 0.074 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like S-AdoMet_synt_C PF02773.11 CDJ69773.1 - 6.2e-66 220.3 0.3 1.7e-65 218.9 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CDJ69773.1 - 1.3e-50 170.3 0.0 2.4e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CDJ69773.1 - 5.9e-43 145.1 0.2 1.2e-42 144.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DUF2312 PF10073.4 CDJ69773.1 - 0.12 11.7 0.2 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) RAP1 PF07218.6 CDJ69774.1 - 2 6.3 3.7 4.2 5.3 2.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Phostensin_N PF13916.1 CDJ69774.1 - 8 6.5 19.3 5.4 7.0 0.9 3.9 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Zip PF02535.17 CDJ69775.1 - 0.074 12.0 2.3 0.072 12.0 0.6 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter PRP1_N PF06424.7 CDJ69775.1 - 3.5 7.9 13.5 0.27 11.5 2.9 3.0 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal DUF912 PF06024.7 CDJ69775.1 - 4.5 7.3 9.3 16 5.5 1.2 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Maf1 PF09174.5 CDJ69775.1 - 7.2 6.4 8.5 0.47 10.2 0.9 2.4 3 0 0 3 3 3 0 Maf1 regulator Tcf25 PF04910.9 CDJ69776.1 - 0.0018 17.2 0.1 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 VirE2 PF07229.7 CDJ69776.1 - 0.0067 14.8 0.0 0.0097 14.3 0.0 1.1 1 0 0 1 1 1 1 VirE2 IncA PF04156.9 CDJ69776.1 - 1.8 8.1 13.9 0.047 13.2 0.6 2.7 2 1 0 2 2 2 0 IncA protein IncA PF04156.9 CDJ69777.1 - 0.0063 16.1 1.5 0.0094 15.5 1.1 1.2 1 0 0 1 1 1 1 IncA protein Calc_CGRP_IAPP PF00214.14 CDJ69777.1 - 0.032 14.2 0.9 0.056 13.4 0.6 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family T2SM PF04612.7 CDJ69777.1 - 0.1 12.3 0.2 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Uso1_p115_head PF04869.9 CDJ69777.1 - 0.13 10.9 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region Mg_trans_NIPA PF05653.9 CDJ69779.1 - 4.8e-14 52.0 4.7 5.9e-14 51.7 3.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CDJ69779.1 - 5.7e-06 26.3 6.3 5.7e-06 26.3 4.4 2.2 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 CDJ69779.1 - 0.00039 20.5 6.0 0.00039 20.5 4.1 2.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Presenilin PF01080.12 CDJ69780.1 - 4.4 6.0 14.3 5.1 5.8 9.9 1.1 1 0 0 1 1 1 0 Presenilin RCC1 PF00415.13 CDJ69783.1 - 1.5e-40 137.1 20.0 3.5e-12 46.3 0.1 9.2 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDJ69783.1 - 1.1e-11 44.0 47.4 0.0019 17.7 0.9 9.2 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RAB3GAP2_N PF14655.1 CDJ69783.1 - 0.11 11.4 0.6 0.2 10.5 0.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pex14_N PF04695.8 CDJ69783.1 - 5.2 7.1 21.4 1.1 9.3 2.6 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UPRTase PF14681.1 CDJ69785.1 - 3.2e-56 189.8 0.4 1.6e-54 184.2 0.0 2.2 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CDJ69785.1 - 4.9e-07 29.4 0.0 1.5e-06 27.9 0.0 1.6 1 1 1 2 2 2 1 Phosphoribosyl transferase domain Pex14_N PF04695.8 CDJ69786.1 - 0.00099 19.1 15.5 0.075 13.0 0.6 2.8 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.1 CDJ69786.1 - 0.005 16.5 1.4 0.26 10.9 0.0 2.3 2 0 0 2 2 2 1 FAM176 family Spt20 PF12090.3 CDJ69786.1 - 0.012 14.9 1.5 0.021 14.1 1.0 1.3 1 0 0 1 1 1 0 Spt20 family Folate_carrier PF01770.13 CDJ69786.1 - 0.25 9.7 3.3 0.35 9.3 1.6 1.6 2 0 0 2 2 2 0 Reduced folate carrier DUF912 PF06024.7 CDJ69786.1 - 0.29 11.2 1.6 20 5.2 1.4 2.7 3 0 0 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2217 PF10265.4 CDJ69786.1 - 0.36 9.5 16.5 0.39 9.4 3.5 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) DDHD PF02862.12 CDJ69786.1 - 0.38 10.5 5.6 1 9.0 0.9 2.2 2 0 0 2 2 2 0 DDHD domain Apt1 PF10351.4 CDJ69786.1 - 0.99 8.1 8.5 6.3 5.5 0.1 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain TMEM51 PF15345.1 CDJ69786.1 - 1.6 8.3 20.0 0.26 10.9 0.6 3.2 3 1 1 4 4 3 0 Transmembrane protein 51 FimP PF09766.4 CDJ69786.1 - 2.4 7.1 14.7 4.3 6.3 10.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein SHR3_chaperone PF08229.6 CDJ69786.1 - 2.8 6.8 4.6 6.2 5.7 3.2 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 SR-25 PF10500.4 CDJ69786.1 - 3 7.2 35.1 2.9 7.2 13.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1645 PF07816.6 CDJ69786.1 - 4.5 7.7 26.5 0.32 11.4 6.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) TAF4 PF05236.9 CDJ69786.1 - 5 6.3 20.4 7 5.8 1.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Suf PF05843.9 CDJ69786.1 - 7.8 6.1 12.4 0.16 11.6 3.1 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DnaJ PF00226.26 CDJ69788.1 - 6.4e-07 29.0 1.7 8.2e-07 28.6 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain Macoilin PF09726.4 CDJ69788.1 - 0.0012 17.1 12.3 0.0015 16.9 8.5 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF1635 PF07795.6 CDJ69788.1 - 0.0063 15.9 4.6 0.0063 15.9 3.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1635) Tir_receptor_N PF07490.6 CDJ69788.1 - 0.0064 16.1 1.4 0.011 15.4 1.0 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus DUF2217 PF10265.4 CDJ69788.1 - 0.096 11.4 11.2 0.11 11.1 7.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CDJ69788.1 - 0.33 9.0 8.7 0.4 8.7 6.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BTV_NS2 PF04514.7 CDJ69788.1 - 0.36 9.6 4.7 0.43 9.4 3.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF755 PF05501.6 CDJ69788.1 - 0.66 10.0 26.8 0.34 10.9 15.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SAPS PF04499.10 CDJ69788.1 - 0.68 8.4 6.4 0.82 8.2 4.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SR-25 PF10500.4 CDJ69788.1 - 1.7 8.1 36.1 0.081 12.3 19.5 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.2 CDJ69788.1 - 1.8 6.1 8.9 1.9 6.0 6.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 CDJ69788.1 - 2.5 7.9 20.6 3.1 7.6 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.12 CDJ69788.1 - 2.7 6.7 8.1 3.3 6.4 5.6 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.6 CDJ69788.1 - 3.2 5.9 9.7 3.9 5.6 6.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_viral_N PF00242.12 CDJ69788.1 - 3.4 6.5 15.5 4.4 6.2 10.8 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PAT1 PF09770.4 CDJ69788.1 - 3.5 5.7 23.5 3.9 5.5 16.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPT16 PF08644.6 CDJ69789.1 - 1.4e-34 119.1 0.4 1.4e-34 119.1 0.3 4.0 3 1 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) WD40 PF00400.27 CDJ69789.1 - 1.1e-29 101.1 3.4 1.1e-08 34.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Rtt106 PF08512.7 CDJ69789.1 - 1.9e-15 56.5 0.0 7.6e-15 54.6 0.0 2.1 1 0 0 1 1 1 1 Histone chaperone Rttp106-like FACT-Spt16_Nlob PF14826.1 CDJ69789.1 - 3.9e-15 55.7 0.0 2.2e-14 53.3 0.0 2.4 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CDJ69789.1 - 5.7e-13 48.9 3.5 2.6e-07 30.4 0.0 3.8 2 2 2 4 4 4 2 Metallopeptidase family M24 Nup160 PF11715.3 CDJ69789.1 - 0.00017 19.8 0.0 0.18 9.9 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF4231 PF14015.1 CDJ69790.1 - 0.029 14.3 5.0 0.034 14.1 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) RAB3GAP2_N PF14655.1 CDJ69790.1 - 4.1 6.3 9.0 4.3 6.2 6.2 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Activator_LAG-3 PF11498.3 CDJ69792.1 - 2.6 6.7 7.1 5.7 5.5 4.9 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3498 PF12004.3 CDJ69792.1 - 2.9 6.9 7.8 3.7 6.5 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3498) Methyltransf_16 PF10294.4 CDJ69793.1 - 3.2e-06 26.6 0.0 5.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Med15 PF09606.5 CDJ69794.1 - 4.9e-06 25.0 224.0 0.0085 14.3 82.7 4.3 4 0 0 4 4 4 4 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDJ69794.1 - 3.3e-05 23.4 11.5 3.3e-05 23.4 8.0 7.2 7 2 0 7 7 7 2 Nuclear RNA-splicing-associated protein CobT PF06213.7 CDJ69794.1 - 0.0044 16.1 3.3 0.0044 16.1 2.3 4.6 4 1 0 4 4 4 1 Cobalamin biosynthesis protein CobT PEX11 PF05648.9 CDJ69794.1 - 0.0049 16.1 2.6 0.0049 16.1 1.8 6.9 6 2 1 7 7 7 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4355 PF14265.1 CDJ69794.1 - 0.018 14.9 0.5 0.018 14.9 0.4 7.1 5 2 0 5 5 5 0 Domain of unknown function (DUF4355) CRT10 PF08728.5 CDJ69794.1 - 4.6 5.1 18.7 1.4 6.8 0.5 2.4 2 0 0 2 2 2 0 CRT10 Collagen PF01391.13 CDJ69795.1 - 0.00017 21.0 9.3 0.00029 20.3 6.4 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Med15 PF09606.5 CDJ69795.1 - 1.2 7.3 20.7 1.5 6.9 14.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ThiF PF00899.16 CDJ69796.1 - 3.2e-24 85.3 10.9 1.9e-20 73.1 0.2 2.8 2 1 1 3 3 3 2 ThiF family Rhodanese PF00581.15 CDJ69796.1 - 6.5e-05 23.2 0.1 0.003 17.8 0.0 3.2 3 0 0 3 3 3 1 Rhodanese-like domain Macoilin PF09726.4 CDJ69796.1 - 6.7 4.8 5.6 12 4.0 3.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Cupin_8 PF13621.1 CDJ69797.1 - 6.3e-32 111.0 0.0 1.1e-26 93.8 0.0 2.2 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.7 CDJ69797.1 - 7.6e-10 38.5 0.1 4.9e-06 26.0 0.0 3.4 4 0 0 4 4 4 2 Cupin superfamily protein Collagen PF01391.13 CDJ69797.1 - 1.2e-06 27.9 78.4 0.0002 20.8 23.3 3.7 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Ribosomal_60s PF00428.14 CDJ69797.1 - 4.6e-05 23.7 4.7 4.6e-05 23.7 3.2 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein JmjC PF02373.17 CDJ69797.1 - 0.0039 17.4 1.6 0.015 15.5 0.0 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase Activator_LAG-3 PF11498.3 CDJ69797.1 - 0.033 12.9 13.9 0.071 11.8 9.6 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SR-25 PF10500.4 CDJ69797.1 - 3.8 6.9 23.1 2.7 7.3 9.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Plasmodium_Vir PF05795.6 CDJ69798.1 - 7.4 5.6 6.5 8 5.5 4.5 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Shisa PF13908.1 CDJ69798.1 - 8.9 6.4 12.3 12 6.0 8.5 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Cwf_Cwc_15 PF04889.7 CDJ69798.1 - 9 5.9 8.4 11 5.6 5.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Saccharop_dh PF03435.13 CDJ69799.1 - 2.7e-05 23.3 0.0 4.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase SR-25 PF10500.4 CDJ69799.1 - 0.011 15.2 10.4 0.017 14.6 7.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2217 PF10265.4 CDJ69799.1 - 3 6.5 6.2 4.6 5.8 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CDJ69799.1 - 5.3 5.0 9.6 7.1 4.5 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 CDJ69800.1 - 0.18 11.2 2.5 0.56 9.6 1.7 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CobN-Mg_chel PF02514.11 CDJ69801.1 - 0.00011 19.7 4.5 0.00014 19.4 3.1 1.1 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Presenilin PF01080.12 CDJ69801.1 - 0.089 11.6 8.0 0.22 10.3 5.6 1.6 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.1 CDJ69801.1 - 1.1 7.3 8.4 2 6.4 5.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.7 CDJ69801.1 - 8.9 6.1 34.4 0.24 11.2 17.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FbpA PF05833.6 CDJ69802.1 - 0.033 12.7 80.0 0.069 11.6 31.6 5.4 3 2 0 3 3 3 0 Fibronectin-binding protein A N-terminus (FbpA) GP41 PF00517.12 CDJ69802.1 - 0.22 11.0 0.0 0.22 11.0 0.0 7.9 8 0 0 8 8 8 0 Retroviral envelope protein Choline_kinase PF01633.15 CDJ69803.1 - 8.9e-22 77.6 0.0 2.7e-17 63.0 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase GRP PF07172.6 CDJ69803.1 - 0.028 14.8 2.4 0.028 14.8 1.7 1.8 2 0 0 2 2 2 0 Glycine rich protein family EcKinase PF02958.15 CDJ69803.1 - 0.069 12.2 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Ecdysteroid kinase Spt20 PF12090.3 CDJ69803.1 - 0.16 11.2 2.9 3 7.1 0.1 2.2 2 0 0 2 2 2 0 Spt20 family Macoilin PF09726.4 CDJ69803.1 - 0.99 7.6 10.6 2 6.5 7.3 1.5 1 0 0 1 1 1 0 Transmembrane protein RAB3GAP2_N PF14655.1 CDJ69803.1 - 2.7 6.9 7.2 9 5.1 1.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TPR_11 PF13414.1 CDJ69804.1 - 7.3e-08 31.9 1.2 7.3e-08 31.9 0.8 2.9 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 CDJ69804.1 - 5.7e-07 29.2 1.2 0.0027 17.7 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ69804.1 - 1.5e-05 24.4 4.1 0.00014 21.5 0.6 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ69804.1 - 2.1e-05 23.9 5.4 2.1e-05 23.8 0.5 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDJ69804.1 - 2.2e-05 24.9 1.8 2.2e-05 24.9 1.3 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDJ69804.1 - 0.00082 18.9 0.5 0.0029 17.2 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 CDJ69804.1 - 0.003 17.6 0.1 0.003 17.6 0.1 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDJ69804.1 - 0.036 13.9 0.1 0.036 13.9 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CDJ69804.1 - 0.09 12.6 2.5 2.2 8.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.9 CDJ69805.1 - 0.47 10.1 4.8 0.51 10.0 3.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Fe_bilin_red PF05996.7 CDJ69805.1 - 9.1 5.6 10.3 2.2 7.6 3.7 1.9 1 1 1 2 2 2 0 Ferredoxin-dependent bilin reductase Claudin_2 PF13903.1 CDJ69806.1 - 0.00019 21.1 0.5 0.00019 21.1 0.4 2.3 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction TTL PF03133.10 CDJ69807.1 - 7.2e-47 159.7 0.0 7.2e-47 159.7 0.0 2.2 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CDJ69807.1 - 2.4e-05 23.2 0.0 2.4e-05 23.2 0.0 3.8 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CDJ69807.1 - 0.0005 19.8 0.0 0.0077 15.9 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain Pyr_redox_2 PF07992.9 CDJ69809.1 - 4.3e-16 59.3 0.0 3.7e-06 26.9 0.0 3.3 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDJ69809.1 - 1.3e-11 44.6 0.0 1.2e-08 35.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CDJ69809.1 - 0.00036 20.6 0.0 5.9 6.8 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DUF3446 PF11928.3 CDJ69809.1 - 0.0046 17.1 0.5 0.0046 17.1 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3446) NAD_binding_7 PF13241.1 CDJ69809.1 - 0.0098 16.1 0.0 0.21 11.8 0.0 2.4 1 1 0 2 2 2 1 Putative NAD(P)-binding Sporozoite_P67 PF05642.6 CDJ69809.1 - 0.11 10.3 0.0 0.16 9.7 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AzlD PF05437.7 CDJ69809.1 - 0.2 11.5 1.5 0.45 10.4 1.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) MMS1_N PF10433.4 CDJ69810.1 - 0.11 10.5 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term RE_XcyI PF09571.5 CDJ69810.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 XcyI restriction endonuclease Cwf_Cwc_15 PF04889.7 CDJ69811.1 - 0.071 12.8 29.7 0.17 11.5 5.4 2.9 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PAN_4 PF14295.1 CDJ69812.1 - 1.9e-06 27.4 0.6 3.4e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 PAN domain Carbpep_Y_N PF05388.6 CDJ69813.1 - 0.035 14.2 1.7 0.035 14.2 1.2 2.4 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide SPARC_Ca_bdg PF10591.4 CDJ69813.1 - 0.04 13.9 0.8 0.04 13.9 0.5 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region NAAA-beta PF15508.1 CDJ69813.1 - 0.1 12.9 2.2 0.12 12.6 0.2 2.0 2 1 1 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SOBP PF15279.1 CDJ69813.1 - 0.86 9.9 6.5 1 9.6 4.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Perilipin PF03036.11 CDJ69813.1 - 0.94 8.2 18.2 1.2 7.9 12.6 1.1 1 0 0 1 1 1 0 Perilipin family AHSP PF09236.5 CDJ69813.1 - 1 9.6 7.9 0.34 11.1 2.0 2.6 1 1 2 3 3 3 0 Alpha-haemoglobin stabilising protein Cytomega_UL84 PF06284.6 CDJ69813.1 - 1.4 7.2 6.9 1.6 7.0 4.8 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF4400 PF14348.1 CDJ69813.1 - 3.1 7.1 4.9 4.9 6.4 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PspA_IM30 PF04012.7 CDJ69813.1 - 3.8 6.8 35.3 0.076 12.3 7.7 2.1 1 1 1 2 2 2 0 PspA/IM30 family MIS13 PF08202.6 CDJ69813.1 - 5 6.1 21.1 6 5.8 14.1 1.3 1 1 0 1 1 1 0 Mis12-Mtw1 protein family DUF4653 PF15546.1 CDJ69814.1 - 0.00077 18.8 4.2 0.00094 18.5 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) SOBP PF15279.1 CDJ69814.1 - 0.011 16.2 5.4 0.011 16.1 3.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF605 PF04652.11 CDJ69814.1 - 0.011 15.2 7.6 0.011 15.1 5.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF4636 PF15468.1 CDJ69814.1 - 0.017 14.5 2.6 0.026 13.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF900 PF05990.7 CDJ69814.1 - 0.034 13.4 0.1 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) CAF-1_p150 PF11600.3 CDJ69814.1 - 0.034 13.5 11.4 0.046 13.1 7.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pex14_N PF04695.8 CDJ69814.1 - 0.042 13.8 11.5 0.078 13.0 8.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDJ69814.1 - 0.045 13.4 4.7 0.048 13.3 3.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1675 PF07897.6 CDJ69814.1 - 0.088 12.6 4.8 0.096 12.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Corona_nucleoca PF00937.13 CDJ69814.1 - 0.63 8.9 12.1 0.75 8.6 8.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF822 PF05687.8 CDJ69814.1 - 0.92 9.8 8.4 1.4 9.3 5.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Paramyxo_C PF01692.13 CDJ69814.1 - 1.7 8.1 8.4 2.1 7.9 5.8 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c SR-25 PF10500.4 CDJ69814.1 - 2 7.8 28.9 5.3 6.4 20.0 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_DNAp_acc PF04929.7 CDJ69814.1 - 6.3 5.6 10.5 8.1 5.2 7.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor LysM PF01476.15 CDJ69815.1 - 1.2e-08 34.6 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 LysM domain DUF3597 PF12200.3 CDJ69815.1 - 0.14 12.5 0.5 0.38 11.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) RRM_1 PF00076.17 CDJ69816.1 - 1.2e-07 31.2 0.0 1.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ69816.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 CDJ69816.1 - 1.5 8.8 7.8 2.3 8.2 5.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med3 PF11593.3 CDJ69816.1 - 7.9 5.6 13.1 10 5.2 9.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DEAD PF00270.24 CDJ69817.1 - 1.2e-17 63.8 0.2 1.2e-17 63.8 0.2 3.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ69817.1 - 9.6e-16 57.4 0.1 9.6e-16 57.4 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain FAD_binding_2 PF00890.19 CDJ69818.1 - 1.8e-71 241.2 4.1 2.3e-49 168.3 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Thi4 PF01946.12 CDJ69818.1 - 0.00017 20.7 0.9 0.038 13.0 0.1 2.4 2 1 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 CDJ69818.1 - 0.0029 17.5 0.6 0.009 15.9 0.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CDJ69818.1 - 0.031 13.1 2.0 0.046 12.5 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 CDJ69818.1 - 0.15 10.4 0.7 0.25 9.7 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Epimerase_Csub PF13950.1 CDJ69818.1 - 0.73 9.8 3.3 0.34 10.8 0.3 1.9 2 0 0 2 2 2 0 UDP-glucose 4-epimerase C-term subunit FUSC PF04632.7 CDJ69820.1 - 0.66 8.3 7.2 0.99 7.7 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3552 PF12072.3 CDJ69821.1 - 0.058 12.6 0.3 0.09 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ripply PF14998.1 CDJ69823.1 - 0.0025 17.8 0.2 0.0025 17.8 0.1 4.0 4 0 0 4 4 4 1 Transcription Regulator Suf PF05843.9 CDJ69823.1 - 3.5 7.2 24.8 1.7 8.3 1.8 4.2 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) HTH_32 PF13565.1 CDJ69823.1 - 8.5 7.2 13.8 0.11 13.2 2.4 3.2 3 1 2 5 5 5 0 Homeodomain-like domain DUF4131 PF13567.1 CDJ69824.1 - 0.0008 18.8 4.1 0.0008 18.8 2.8 6.1 4 2 1 5 5 5 3 Domain of unknown function (DUF4131) DUF3246 PF11596.3 CDJ69826.1 - 0.18 11.1 4.9 0.25 10.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NSP2-B_epitope PF14757.1 CDJ69826.1 - 0.22 10.9 12.2 0.26 10.7 8.4 1.0 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF755 PF05501.6 CDJ69826.1 - 0.86 9.6 13.5 1.1 9.3 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Period_C PF12114.3 CDJ69826.1 - 1 8.9 9.2 1.2 8.6 6.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.4 CDJ69826.1 - 9.9 5.5 23.1 14 5.0 15.9 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CBM_25 PF03423.8 CDJ69827.1 - 3.5e-05 23.8 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) S6PP PF05116.8 CDJ69827.1 - 0.044 13.0 1.4 0.11 11.7 1.0 1.7 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Hex_IIIa PF02455.11 CDJ69827.1 - 0.045 12.4 4.7 0.057 12.0 3.3 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Pex14_N PF04695.8 CDJ69827.1 - 0.24 11.4 10.2 0.36 10.8 2.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TSA PF03249.8 CDJ69827.1 - 0.53 8.7 8.8 0.69 8.3 6.1 1.1 1 0 0 1 1 1 0 Type specific antigen CDK2AP PF09806.4 CDJ69827.1 - 0.61 10.2 19.3 3.3 7.9 0.7 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.8 CDJ69827.1 - 1.3 7.8 9.2 1.5 7.6 6.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ArfGap PF01412.13 CDJ69828.1 - 6.7e-22 77.4 1.8 9.8e-15 54.3 0.3 3.2 4 1 0 4 4 4 2 Putative GTPase activating protein for Arf BAF1_ABF1 PF04684.8 CDJ69828.1 - 0.002 17.0 6.0 0.002 17.0 4.1 6.6 4 2 2 6 6 6 2 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CDJ69828.1 - 0.89 8.8 24.7 1.9 7.7 0.1 4.1 4 0 0 4 4 4 0 Spt20 family Collagen PF01391.13 CDJ69829.1 - 0.12 11.9 12.2 0.32 10.5 8.4 1.7 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Clat_adaptor_s PF01217.15 CDJ69830.1 - 1.6e-44 151.0 0.9 2.5e-42 143.9 0.6 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Med15 PF09606.5 CDJ69831.1 - 0.0028 15.9 9.8 0.0028 15.9 6.8 2.7 2 1 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal PPR_3 PF13812.1 CDJ69831.1 - 0.024 14.8 0.1 0.1 12.9 0.0 2.2 1 0 0 1 1 1 0 Pentatricopeptide repeat domain eIF_4EBP PF05456.6 CDJ69831.1 - 0.046 13.4 0.6 0.046 13.4 0.4 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PPR_2 PF13041.1 CDJ69831.1 - 0.047 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family BAF1_ABF1 PF04684.8 CDJ69831.1 - 6.8 5.4 30.1 0.3 9.9 3.6 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 CDJ69831.1 - 9.2 4.3 41.5 2.2 6.4 16.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 GCV_H PF01597.14 CDJ69832.1 - 0.003 17.2 0.0 0.0073 15.9 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein Spt20 PF12090.3 CDJ69832.1 - 0.15 11.4 11.8 0.65 9.3 2.5 2.4 2 0 0 2 2 2 0 Spt20 family SAGA-Tad1 PF12767.2 CDJ69832.1 - 0.18 11.4 13.6 0.42 10.2 4.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Spt20 PF12090.3 CDJ69833.1 - 0.58 9.4 4.0 1.7 7.9 1.4 2.0 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.5 CDJ69834.1 - 0.00085 17.6 22.7 0.00099 17.4 15.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal HlyD_2 PF12700.2 CDJ69834.1 - 0.01 15.0 0.9 0.014 14.5 0.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Spt20 PF12090.3 CDJ69834.1 - 0.024 13.9 2.4 0.035 13.4 1.6 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDJ69834.1 - 0.051 13.2 8.4 0.06 13.0 5.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PH_BEACH PF14844.1 CDJ69834.1 - 0.076 12.8 1.5 0.13 12.1 1.0 1.4 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH AAA_23 PF13476.1 CDJ69834.1 - 0.61 10.3 6.5 10 6.3 3.3 2.0 2 0 0 2 2 2 0 AAA domain TFIIA PF03153.8 CDJ69834.1 - 1.2 8.9 16.2 1.4 8.7 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ69834.1 - 1.9 6.5 23.4 2.3 6.3 16.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDJ69834.1 - 2.2 8.7 13.2 5.5 7.4 9.1 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein DSPn PF14671.1 CDJ69836.1 - 3.7e-19 69.0 0.1 7.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Methyltransf_26 PF13659.1 CDJ69836.1 - 1.3e-12 47.7 2.0 1.3e-12 47.7 1.4 3.3 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ69836.1 - 4e-10 40.2 0.1 1.6e-09 38.3 0.1 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_SAM PF10672.4 CDJ69836.1 - 4.5e-10 38.8 0.0 1.8e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 S-adenosylmethionine-dependent methyltransferase DSPc PF00782.15 CDJ69836.1 - 4.6e-09 35.9 0.3 2.2e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain MTS PF05175.9 CDJ69836.1 - 6.4e-08 32.1 0.4 0.00016 21.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 CDJ69836.1 - 0.00011 21.8 0.0 0.67 9.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.8 CDJ69836.1 - 0.00031 19.9 0.1 0.00066 18.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Y_phosphatase PF00102.22 CDJ69836.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Methyltransf_25 PF13649.1 CDJ69836.1 - 0.0022 18.3 0.0 0.0099 16.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ69836.1 - 0.012 16.1 2.1 0.45 11.0 0.1 3.5 3 1 0 3 3 2 0 Methyltransferase domain PTPlike_phytase PF14566.1 CDJ69836.1 - 0.018 15.0 0.7 0.039 13.9 0.0 1.8 2 0 0 2 2 1 0 Inositol hexakisphosphate Cons_hypoth95 PF03602.10 CDJ69836.1 - 0.14 11.5 11.3 0.19 11.1 0.3 2.6 2 1 1 3 3 2 0 Conserved hypothetical protein 95 Y_phosphatase3 PF13350.1 CDJ69836.1 - 0.19 11.9 0.1 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Ubie_methyltran PF01209.13 CDJ69836.1 - 0.26 10.3 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Suf PF05843.9 CDJ69836.1 - 0.81 9.3 3.9 1.4 8.6 2.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pkinase PF00069.20 CDJ69837.1 - 1e-34 119.8 0.0 1.4e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ69837.1 - 5.6e-23 81.3 0.0 9.3e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDJ69837.1 - 0.00096 18.9 1.2 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Exo_endo_phos PF03372.18 CDJ69838.1 - 9.7e-07 28.9 0.0 5.1e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fusion_gly PF00523.13 CDJ69839.1 - 0.23 9.4 0.7 0.32 8.9 0.5 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 COX4_pro PF03626.9 CDJ69840.1 - 1.4 9.0 6.3 1.1 9.3 0.7 3.1 3 0 0 3 3 3 0 Prokaryotic Cytochrome C oxidase subunit IV IMPDH PF00478.20 CDJ69841.1 - 5.4e-129 430.0 0.2 1.5e-128 428.6 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CDJ69841.1 - 9e-14 51.0 0.0 2.3e-06 27.2 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CDJ69841.1 - 6.8e-12 45.1 8.5 1.4e-07 30.9 5.4 2.9 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 CDJ69841.1 - 5.9e-10 38.5 3.4 1.1e-09 37.6 1.1 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CDJ69841.1 - 1.1e-05 24.8 3.0 5e-05 22.6 2.1 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 CDJ69841.1 - 0.0014 17.7 3.3 0.0022 17.0 1.5 1.8 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.9 CDJ69841.1 - 0.0018 17.3 1.6 0.085 11.8 1.1 2.8 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase PcrB PF01884.12 CDJ69841.1 - 0.0051 16.0 3.5 1.6 7.8 0.1 3.6 2 1 2 4 4 4 1 PcrB family TMP-TENI PF02581.12 CDJ69841.1 - 0.021 13.9 2.2 0.27 10.3 1.5 2.4 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI DHO_dh PF01180.16 CDJ69841.1 - 0.025 13.5 0.3 0.025 13.5 0.2 1.9 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase CTP_transf_2 PF01467.21 CDJ69842.1 - 0.048 13.7 0.1 0.35 10.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylyltransferase FAD_syn PF06574.7 CDJ69842.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase NTP_transf_3 PF12804.2 CDJ69843.1 - 2.1e-13 50.6 0.0 4.6e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 CDJ69843.1 - 4.9e-13 48.9 0.0 8.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CDJ69843.1 - 0.0054 16.1 0.1 1.1 8.8 0.0 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.14 CDJ69843.1 - 0.097 12.2 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Cytidylyltransferase TPR_11 PF13414.1 CDJ69845.1 - 6.5e-05 22.4 0.6 6.5e-05 22.4 0.4 2.9 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 CDJ69845.1 - 0.18 11.8 2.0 29 4.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DDHD PF02862.12 CDJ69845.1 - 8.5 6.0 10.1 6 6.5 4.1 2.3 2 0 0 2 2 2 0 DDHD domain DSPc PF00782.15 CDJ69846.1 - 1.8e-07 30.7 0.1 4.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CDJ69846.1 - 0.015 15.5 0.3 0.015 15.5 0.2 3.1 3 0 0 3 3 3 0 Tyrosine phosphatase family Arm PF00514.18 CDJ69847.1 - 5.2e-13 48.2 0.0 0.00097 18.8 0.0 4.3 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDJ69847.1 - 0.00022 21.4 1.1 0.017 15.4 0.2 2.8 1 1 1 2 2 2 2 HEAT repeats WAPL PF07814.8 CDJ69847.1 - 0.0035 16.1 0.0 0.008 14.9 0.0 1.6 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin HEAT PF02985.17 CDJ69847.1 - 0.14 12.2 0.6 58 4.1 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat BAF1_ABF1 PF04684.8 CDJ69848.1 - 0.00021 20.2 21.4 0.00021 20.2 14.8 2.8 1 1 2 3 3 2 1 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.2 CDJ69848.1 - 0.46 8.1 8.7 0.49 8.0 6.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FCP1_C PF09309.5 CDJ69848.1 - 0.56 9.4 14.7 1 8.5 10.2 1.5 1 0 0 1 1 1 0 FCP1, C-terminal DUF966 PF06136.8 CDJ69848.1 - 1 8.6 10.6 1.2 8.4 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDJ69848.1 - 1.1 9.0 6.6 1.3 8.8 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3807 PF12720.2 CDJ69848.1 - 1.1 9.3 16.0 1.4 9.0 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Plasmodium_Vir PF05795.6 CDJ69848.1 - 1.3 8.1 5.3 1.6 7.8 3.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 CDJ69848.1 - 1.3 7.1 11.1 1.5 6.9 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein PLRV_ORF5 PF01690.12 CDJ69848.1 - 3.5 6.6 14.2 4.3 6.3 9.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DDHD PF02862.12 CDJ69848.1 - 4 7.1 8.6 4.8 6.8 6.0 1.3 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.8 CDJ69848.1 - 5.4 6.4 8.9 7.2 6.0 6.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4557 PF15101.1 CDJ69848.1 - 7.1 6.4 19.0 12 5.7 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DDRGK PF09756.4 CDJ69848.1 - 9.5 5.5 17.8 12 5.1 12.4 1.1 1 0 0 1 1 1 0 DDRGK domain RNase_P_p30 PF01876.11 CDJ69849.1 - 1.9e-19 69.3 0.3 1.9e-18 66.1 0.2 2.2 1 1 0 1 1 1 1 RNase P subunit p30 SRP1_TIP1 PF00660.12 CDJ69850.1 - 0.077 12.8 0.1 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 Seripauperin and TIP1 family TSA PF03249.8 CDJ69850.1 - 0.66 8.4 10.0 0.8 8.1 7.0 1.1 1 0 0 1 1 1 0 Type specific antigen UQ_con PF00179.21 CDJ69851.1 - 2.8e-13 49.5 0.0 2.8e-13 49.5 0.0 3.4 3 2 1 4 4 4 1 Ubiquitin-conjugating enzyme RNA_pol_Rpc4 PF05132.9 CDJ69851.1 - 0.0038 17.2 2.9 0.0038 17.2 2.0 5.1 3 1 0 3 3 3 2 RNA polymerase III RPC4 R3H-assoc PF13902.1 CDJ69851.1 - 0.087 12.7 0.4 0.087 12.7 0.3 5.3 3 1 2 5 5 5 0 R3H-associated N-terminal domain Utp14 PF04615.8 CDJ69851.1 - 1.3 7.1 52.8 1.6 6.7 32.4 2.3 2 0 0 2 2 2 0 Utp14 protein zf-C4H2 PF10146.4 CDJ69852.1 - 0.61 10.0 7.0 1.2 9.1 4.9 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein EspB PF05802.6 CDJ69852.1 - 9.5 5.0 15.0 14 4.5 10.4 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF382 PF04037.8 CDJ69855.1 - 0.0081 15.9 0.7 0.16 11.7 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF382) DUF3306 PF11748.3 CDJ69855.1 - 0.06 13.9 1.0 0.071 13.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FdhE PF04216.7 CDJ69855.1 - 0.12 12.0 0.6 0.14 11.8 0.4 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Herpes_UL25 PF01499.11 CDJ69855.1 - 0.22 9.8 1.0 0.23 9.6 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Cauli_DNA-bind PF03310.8 CDJ69856.1 - 0.37 10.6 6.2 0.54 10.1 4.3 1.3 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein Phage_GPO PF05929.6 CDJ69856.1 - 0.92 8.6 15.2 1 8.5 10.5 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PAT1 PF09770.4 CDJ69856.1 - 1.7 6.7 33.8 1.7 6.7 23.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ69856.1 - 1.7 6.7 36.1 1.8 6.6 25.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2336 PF10098.4 CDJ69856.1 - 2.2 7.4 6.1 2.4 7.3 4.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) Band_3_cyto PF07565.8 CDJ69856.1 - 2.4 7.5 12.8 2.8 7.3 8.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.9 CDJ69856.1 - 2.7 7.6 20.1 2.9 7.5 13.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDJ69856.1 - 4.5 6.5 21.9 5 6.4 15.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF4011 PF13195.1 CDJ69856.1 - 5 7.1 10.9 5.9 6.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) EcsC PF12787.2 CDJ69856.1 - 7 5.9 12.7 7.6 5.8 8.8 1.1 1 0 0 1 1 1 0 EcsC protein family Shisa PF13908.1 CDJ69856.1 - 7.1 6.7 12.8 7.5 6.6 8.9 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RAP1 PF07218.6 CDJ69857.1 - 0.92 7.5 8.6 1 7.3 5.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PrgH PF09480.5 CDJ69858.1 - 0.064 12.1 13.7 0.095 11.5 9.5 1.3 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) CD20 PF04103.10 CDJ69858.1 - 0.31 10.9 7.3 0.62 9.9 0.2 2.4 2 0 0 2 2 2 0 CD20-like family IncA PF04156.9 CDJ69858.1 - 3.6 7.1 46.8 0.037 13.6 7.8 2.4 2 0 0 2 2 2 0 IncA protein Spt20 PF12090.3 CDJ69858.1 - 8.4 5.6 22.2 0.24 10.7 2.9 2.5 3 0 0 3 3 3 0 Spt20 family MCM PF00493.18 CDJ69859.1 - 8.2e-25 87.3 0.3 4e-24 85.0 0.0 2.1 1 1 1 2 2 2 1 MCM2/3/5 family G-alpha PF00503.15 CDJ69859.1 - 0.0067 15.1 1.4 0.41 9.2 0.1 2.0 2 0 0 2 2 2 2 G-protein alpha subunit VAD1-2 PF15310.1 CDJ69859.1 - 0.043 13.4 1.7 0.053 13.1 0.1 1.7 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling DUF2360 PF10152.4 CDJ69859.1 - 4.1 7.6 7.0 0.93 9.7 1.7 1.9 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SR-25 PF10500.4 CDJ69860.1 - 0.0045 16.5 13.6 0.0045 16.5 9.4 3.0 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein SAPS PF04499.10 CDJ69860.1 - 0.023 13.3 15.0 0.022 13.3 10.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Exonuc_VII_L PF02601.10 CDJ69860.1 - 0.038 13.1 16.1 0.043 13.0 11.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.11 CDJ69860.1 - 0.079 11.5 4.9 0.09 11.3 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HlyD_2 PF12700.2 CDJ69860.1 - 0.095 11.8 18.3 0.094 11.8 12.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein PLRV_ORF5 PF01690.12 CDJ69860.1 - 0.1 11.7 28.0 0.16 11.1 19.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Dicty_REP PF05086.7 CDJ69860.1 - 0.2 9.3 13.1 0.18 9.5 9.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CRT10 PF08728.5 CDJ69860.1 - 0.73 7.7 9.4 0.66 7.8 6.5 1.1 1 0 0 1 1 1 0 CRT10 Metallophos PF00149.23 CDJ69861.1 - 6e-36 123.7 0.1 8.1e-36 123.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDJ69861.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Transketolase_C PF02780.15 CDJ69862.1 - 8.9e-19 67.6 1.0 2.2e-16 59.8 0.1 3.0 2 0 0 2 2 2 2 Transketolase, C-terminal domain AAA_16 PF13191.1 CDJ69862.1 - 0.00013 22.0 4.7 0.00013 22.0 3.3 4.9 3 1 1 4 4 4 1 AAA ATPase domain Arch_ATPase PF01637.13 CDJ69862.1 - 0.0047 16.6 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 CDJ69862.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 CDJ69862.1 - 2.3 8.5 5.8 37 4.5 4.0 2.3 2 0 0 2 2 2 0 AAA domain Mcm10 PF09332.6 CDJ69862.1 - 8 5.6 16.7 0.47 9.7 6.7 2.1 2 0 0 2 2 2 0 Mcm10 replication factor Utp21 PF04192.7 CDJ69863.1 - 2.6e-14 52.9 0.8 2.6e-14 52.9 0.5 4.1 4 0 0 4 4 4 1 Utp21 specific WD40 associated putative domain SR-25 PF10500.4 CDJ69863.1 - 0.0048 16.4 20.7 0.0048 16.4 14.3 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Herpes_UL87 PF03043.9 CDJ69863.1 - 0.005 15.2 0.0 0.013 13.9 0.0 1.6 1 1 0 1 1 1 1 Herpesvirus UL87 family DUF3446 PF11928.3 CDJ69863.1 - 0.086 13.0 13.3 0.54 10.4 9.2 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Mem_trans PF03547.13 CDJ69863.1 - 0.68 8.1 2.5 7.4 4.7 1.0 2.2 2 0 0 2 2 2 0 Membrane transport protein Gti1_Pac2 PF09729.4 CDJ69863.1 - 7.7 6.3 18.7 0.75 9.6 0.0 2.8 3 0 0 3 3 3 0 Gti1/Pac2 family PHD PF00628.24 CDJ69864.1 - 1.5e-11 43.7 7.8 1.5e-11 43.7 5.4 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 CDJ69864.1 - 6.2e-11 41.4 3.6 6.2e-11 41.4 2.5 2.2 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 CDJ69864.1 - 0.007 16.0 1.1 0.007 16.0 0.7 2.6 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FlaF PF07309.6 CDJ69864.1 - 0.024 14.5 0.2 0.045 13.6 0.2 1.4 1 0 0 1 1 1 0 Flagellar protein FlaF Prok-RING_1 PF14446.1 CDJ69864.1 - 0.052 13.2 12.0 0.048 13.3 6.9 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.2 CDJ69864.1 - 0.15 11.9 7.7 2.3 8.1 0.6 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-UDP PF14569.1 CDJ69864.1 - 0.34 10.6 5.5 0.41 10.4 3.0 1.7 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-PHD-like PF15446.1 CDJ69864.1 - 1.3 8.2 14.9 0.43 9.8 8.2 1.9 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-B_box PF00643.19 CDJ69864.1 - 8.6 6.3 9.3 12 5.9 0.5 2.9 2 1 0 2 2 2 0 B-box zinc finger Activator_LAG-3 PF11498.3 CDJ69865.1 - 0.027 13.2 1.2 0.036 12.8 0.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Cpn60_TCP1 PF00118.19 CDJ69866.1 - 1.1e-62 212.2 0.0 1.2e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family VCBS PF13517.1 CDJ69868.1 - 3.8e-19 68.8 0.6 1.7e-06 28.3 0.2 6.9 6 1 1 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CDJ69868.1 - 9.8e-16 56.9 16.5 1.1e-05 24.9 0.3 6.7 6 0 0 6 6 6 5 FG-GAP repeat FimP PF09766.4 CDJ69868.1 - 0.0025 16.9 0.9 0.0025 16.9 0.6 4.0 5 0 0 5 5 5 1 Fms-interacting protein ODV-E18 PF10717.4 CDJ69868.1 - 0.82 9.1 0.0 0.82 9.1 0.0 4.0 3 1 1 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 AAA_23 PF13476.1 CDJ69868.1 - 1.3 9.3 17.7 0.14 12.4 0.3 3.1 3 0 0 3 3 3 0 AAA domain Rxt3 PF08642.5 CDJ69868.1 - 4.9 7.4 6.8 3 8.1 0.3 3.2 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 EphA2_TM PF14575.1 CDJ69868.1 - 5.2 7.5 0.0 5.2 7.5 0.0 4.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 CDJ69869.1 - 2.5e-15 56.3 0.0 1.6e-07 30.7 0.0 4.1 3 1 1 4 4 4 3 Protein kinase domain Kinase-like PF14531.1 CDJ69869.1 - 3.9e-07 29.3 1.6 0.029 13.3 0.9 3.5 3 1 0 3 3 3 3 Kinase-like Pkinase_Tyr PF07714.12 CDJ69869.1 - 9.3e-06 24.8 0.0 0.036 13.1 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.2 CDJ69870.1 - 1.7e-16 59.4 12.5 2e-06 27.2 0.2 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDJ69870.1 - 4.2e-07 29.6 22.6 1.9e-05 24.3 2.1 3.7 2 1 3 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CDJ69870.1 - 0.00033 20.2 14.1 2.4 8.5 0.0 6.0 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CDJ69870.1 - 0.0016 18.2 14.5 1.4 9.3 0.1 6.4 5 1 1 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 CDJ69870.1 - 0.023 14.7 14.5 1.4 9.2 0.0 5.3 5 1 1 6 6 6 0 Leucine Rich repeat DUF2217 PF10265.4 CDJ69870.1 - 2.9 6.5 6.3 4.2 6.0 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FCP1_C PF09309.5 CDJ69870.1 - 4.6 6.4 9.9 0.064 12.5 1.7 1.6 2 0 0 2 2 2 0 FCP1, C-terminal 7TM_transglut PF14402.1 CDJ69870.1 - 4.6 6.0 7.1 1.4 7.7 0.5 2.1 2 0 0 2 2 2 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF155 PF02582.9 CDJ69871.1 - 8.3e-14 51.8 0.1 8.3e-14 51.8 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Na_trans_assoc PF06512.8 CDJ69871.1 - 4.1 7.3 12.1 6 6.7 8.4 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Macoilin PF09726.4 CDJ69871.1 - 4.5 5.4 24.0 6.9 4.8 16.6 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4207 PF13904.1 CDJ69872.1 - 0.0086 15.4 3.1 0.0086 15.4 2.2 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) AAA_23 PF13476.1 CDJ69872.1 - 0.039 14.2 1.7 0.37 11.0 0.5 2.2 2 0 0 2 2 2 0 AAA domain Rotamase_2 PF13145.1 CDJ69872.1 - 0.16 12.5 6.2 0.95 10.1 0.5 2.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain TFIIA PF03153.8 CDJ69872.1 - 0.17 11.7 20.5 0.64 9.8 2.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 CDJ69872.1 - 0.67 8.8 14.7 0.086 11.8 1.5 2.9 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDJ69872.1 - 2.8 6.0 50.6 0.24 9.5 11.0 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Apt1 PF10351.4 CDJ69872.1 - 9.1 5.0 7.7 24 3.6 5.3 1.7 1 1 0 1 1 1 0 Golgi-body localisation protein domain DUF1645 PF07816.6 CDJ69874.1 - 0.18 12.2 13.5 0.17 12.3 1.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) CD20 PF04103.10 CDJ69876.1 - 0.00054 19.9 1.5 0.00064 19.6 1.1 1.1 1 0 0 1 1 1 1 CD20-like family TRAP_alpha PF03896.11 CDJ69876.1 - 0.00064 18.8 1.4 0.00071 18.6 1.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 CDJ69876.1 - 0.005 14.6 8.1 0.0053 14.5 5.6 1.0 1 0 0 1 1 1 1 Ycf1 U79_P34 PF03064.11 CDJ69876.1 - 0.0057 16.2 5.5 0.0057 16.2 3.8 1.0 1 0 0 1 1 1 1 HSV U79 / HCMV P34 FimP PF09766.4 CDJ69876.1 - 0.0063 15.6 24.3 0.0063 15.6 16.9 1.0 1 0 0 1 1 1 1 Fms-interacting protein DUF533 PF04391.7 CDJ69876.1 - 0.0066 15.8 16.7 0.009 15.4 11.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF533) Shadoo PF14999.1 CDJ69876.1 - 0.0067 16.2 0.1 0.0068 16.2 0.1 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective FHIPEP PF00771.15 CDJ69876.1 - 0.013 13.9 7.2 0.014 13.7 5.0 1.0 1 0 0 1 1 1 0 FHIPEP family IncA PF04156.9 CDJ69876.1 - 0.014 14.9 21.5 0.017 14.7 14.9 1.1 1 0 0 1 1 1 0 IncA protein AIF_C PF14721.1 CDJ69876.1 - 0.014 15.5 10.4 0.017 15.4 7.2 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Serinc PF03348.10 CDJ69876.1 - 0.02 13.6 12.0 0.021 13.5 8.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) VIT1 PF01988.14 CDJ69876.1 - 0.022 14.2 5.4 0.025 14.0 3.7 1.1 1 0 0 1 1 1 0 VIT family FadA PF09403.5 CDJ69876.1 - 0.029 14.3 11.5 0.035 14.1 8.0 1.1 1 0 0 1 1 1 0 Adhesion protein FadA Ctr PF04145.10 CDJ69876.1 - 0.032 14.2 5.8 0.045 13.7 4.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Trp_oprn_chp PF09534.5 CDJ69876.1 - 0.035 13.7 5.0 0.041 13.5 3.4 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ResB PF05140.9 CDJ69876.1 - 0.036 12.6 7.0 0.04 12.4 4.9 1.0 1 0 0 1 1 1 0 ResB-like family SID-1_RNA_chan PF13965.1 CDJ69876.1 - 0.036 12.2 4.7 0.042 12.0 3.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM176 PF14851.1 CDJ69876.1 - 0.039 13.6 2.5 0.045 13.4 1.7 1.1 1 0 0 1 1 1 0 FAM176 family DUF3260 PF11658.3 CDJ69876.1 - 0.044 11.9 10.1 0.049 11.7 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF2422 PF10337.4 CDJ69876.1 - 0.064 12.0 11.6 0.069 11.9 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF3381 PF11861.3 CDJ69876.1 - 0.078 12.4 11.8 0.086 12.3 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3450 PF11932.3 CDJ69876.1 - 0.082 12.1 28.3 0.096 11.9 19.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4628 PF15429.1 CDJ69876.1 - 0.088 12.2 10.4 0.099 12.0 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DUF1980 PF09323.5 CDJ69876.1 - 0.093 12.4 8.9 0.11 12.2 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Choline_transpo PF04515.7 CDJ69876.1 - 0.094 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter YjgP_YjgQ PF03739.9 CDJ69876.1 - 0.097 11.4 1.8 0.14 10.8 1.3 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family YibE_F PF07907.6 CDJ69876.1 - 0.1 11.7 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 YibE/F-like protein Tetraspannin PF00335.15 CDJ69876.1 - 0.11 11.7 1.9 0.14 11.3 1.3 1.2 1 0 0 1 1 1 0 Tetraspanin family Baculo_PP31 PF05311.6 CDJ69876.1 - 0.11 11.7 11.6 0.11 11.7 8.1 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Cyclin_C PF02984.14 CDJ69876.1 - 0.12 12.2 7.8 0.16 11.9 5.4 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF2217 PF10265.4 CDJ69876.1 - 0.13 11.0 7.3 0.13 11.0 5.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3824 PF12868.2 CDJ69876.1 - 0.14 13.1 9.3 0.18 12.7 6.4 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF4557 PF15101.1 CDJ69876.1 - 0.14 11.9 24.1 0.14 11.9 16.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RIC3 PF15361.1 CDJ69876.1 - 0.16 12.2 11.3 0.16 12.1 7.8 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DDHD PF02862.12 CDJ69876.1 - 0.16 11.7 11.9 0.16 11.7 8.3 1.0 1 0 0 1 1 1 0 DDHD domain Gastrin PF00918.12 CDJ69876.1 - 0.2 12.4 16.9 0.25 12.1 11.7 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Folate_carrier PF01770.13 CDJ69876.1 - 0.26 9.7 6.7 0.27 9.6 4.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.15 CDJ69876.1 - 0.29 9.1 9.1 0.33 8.9 6.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sec62 PF03839.11 CDJ69876.1 - 0.34 10.2 5.2 0.32 10.3 3.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 R_equi_Vir PF05526.6 CDJ69876.1 - 0.35 10.5 9.7 0.37 10.4 6.7 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Zip PF02535.17 CDJ69876.1 - 0.36 9.7 2.4 0.4 9.6 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAGA-Tad1 PF12767.2 CDJ69876.1 - 0.37 10.4 14.3 0.35 10.5 9.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Band_3_cyto PF07565.8 CDJ69876.1 - 0.38 10.2 12.3 0.36 10.2 8.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hid1 PF12722.2 CDJ69876.1 - 0.38 8.3 11.3 0.34 8.5 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDJ69876.1 - 0.4 9.1 10.9 0.39 9.1 7.6 1.0 1 0 0 1 1 1 0 Raftlin DUF4175 PF13779.1 CDJ69876.1 - 0.46 8.1 39.2 0.46 8.1 27.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ATG22 PF11700.3 CDJ69876.1 - 0.49 8.7 2.0 0.55 8.6 1.4 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Peroxin-13_N PF04088.8 CDJ69876.1 - 0.52 10.2 6.1 0.63 9.9 4.2 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Presenilin PF01080.12 CDJ69876.1 - 0.52 9.0 7.7 0.56 8.9 5.3 1.1 1 0 0 1 1 1 0 Presenilin Pex16 PF08610.5 CDJ69876.1 - 0.54 9.1 10.3 0.49 9.3 7.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) YABBY PF04690.8 CDJ69876.1 - 0.55 10.4 8.3 0.62 10.2 5.8 1.0 1 0 0 1 1 1 0 YABBY protein Herpes_DNAp_acc PF04929.7 CDJ69876.1 - 0.57 9.0 7.8 0.61 8.9 5.4 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pal1 PF08316.6 CDJ69876.1 - 0.59 10.5 6.8 0.63 10.4 4.7 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF4259 PF14078.1 CDJ69876.1 - 0.61 10.5 6.2 0.71 10.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) FLO_LFY PF01698.11 CDJ69876.1 - 0.63 8.8 14.0 0.66 8.7 9.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2232 PF09991.4 CDJ69876.1 - 0.66 8.9 7.8 0.75 8.7 5.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) YfhO PF09586.5 CDJ69876.1 - 0.69 7.8 8.5 0.77 7.6 5.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO HA2 PF04408.18 CDJ69876.1 - 0.71 9.9 4.9 0.91 9.5 3.4 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Pex14_N PF04695.8 CDJ69876.1 - 0.77 9.8 25.1 0.94 9.5 17.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pex26 PF07163.7 CDJ69876.1 - 0.79 8.5 13.5 0.86 8.4 9.3 1.0 1 0 0 1 1 1 0 Pex26 protein AAA_23 PF13476.1 CDJ69876.1 - 0.83 9.9 16.0 0.79 10.0 11.1 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.11 CDJ69876.1 - 0.87 9.4 6.1 0.88 9.4 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endonuc_Holl PF10107.4 CDJ69876.1 - 0.88 9.2 11.9 0.81 9.3 8.2 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Gag_spuma PF03276.9 CDJ69876.1 - 1 7.6 29.4 1 7.6 20.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein FYDLN_acid PF09538.5 CDJ69876.1 - 1 9.9 7.3 1.2 9.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF3373 PF11853.3 CDJ69876.1 - 1.1 7.7 18.2 1.2 7.5 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) RskA PF10099.4 CDJ69876.1 - 1.1 8.9 20.6 1.8 8.2 14.3 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Mem_trans PF03547.13 CDJ69876.1 - 1.1 7.4 5.5 1.2 7.3 3.8 1.0 1 0 0 1 1 1 0 Membrane transport protein SpoVR PF04293.8 CDJ69876.1 - 1.3 7.3 12.3 1.3 7.2 8.5 1.0 1 0 0 1 1 1 0 SpoVR like protein Dala_Dala_lig_N PF01820.16 CDJ69876.1 - 1.3 9.3 6.7 1.5 9.1 4.6 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF2149 PF09919.4 CDJ69876.1 - 1.4 9.0 7.0 1.4 9.0 4.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF4407 PF14362.1 CDJ69876.1 - 1.4 7.8 20.2 1.5 7.7 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med13_N PF11597.3 CDJ69876.1 - 1.4 7.4 16.9 1.5 7.3 11.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal FPN1 PF06963.7 CDJ69876.1 - 1.5 7.1 5.0 1.7 6.9 3.4 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Dynamin_N PF00350.18 CDJ69876.1 - 1.6 8.5 6.2 1.5 8.6 4.3 1.1 1 0 0 1 1 1 0 Dynamin family MelC1 PF06236.6 CDJ69876.1 - 1.7 8.6 8.6 2.2 8.3 6.0 1.2 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 DUF3357 PF11837.3 CDJ69876.1 - 1.7 8.5 9.5 9.9 6.0 6.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF913 PF06025.7 CDJ69876.1 - 1.8 7.2 8.7 1.9 7.1 6.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_60s PF00428.14 CDJ69876.1 - 1.8 9.0 13.6 2 8.8 9.4 1.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein Tim54 PF11711.3 CDJ69876.1 - 1.8 7.0 11.1 1.9 7.0 7.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Kei1 PF08552.6 CDJ69876.1 - 1.9 8.1 11.7 2.1 7.9 8.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 ABC2_membrane_2 PF12679.2 CDJ69876.1 - 2 7.2 6.1 3 6.6 4.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AUX_IAA PF02309.11 CDJ69876.1 - 2.1 8.0 12.0 2.3 7.9 8.3 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF3573 PF12097.3 CDJ69876.1 - 2.1 6.8 12.5 2.2 6.8 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Plasmodium_Vir PF05795.6 CDJ69876.1 - 2.2 7.4 5.1 2 7.5 3.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2561 PF10812.3 CDJ69876.1 - 2.2 7.8 5.3 2.4 7.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) SeqA PF03925.8 CDJ69876.1 - 2.2 7.9 11.7 2.4 7.8 8.1 1.1 1 0 0 1 1 1 0 SeqA protein Shisa PF13908.1 CDJ69876.1 - 2.2 8.4 14.4 2.2 8.4 10.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2229 PF09989.4 CDJ69876.1 - 2.3 7.6 6.9 2.7 7.4 4.8 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) FNIP_N PF14636.1 CDJ69876.1 - 2.3 8.6 14.8 2.7 8.4 10.2 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Peptidase_S49_N PF08496.5 CDJ69876.1 - 2.5 7.9 13.0 3 7.5 9.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CRF1 PF10380.4 CDJ69876.1 - 2.5 8.4 9.2 2.9 8.2 6.4 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 CPSF100_C PF13299.1 CDJ69876.1 - 2.6 8.2 11.8 2.6 8.2 8.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Cellulose_synt PF03552.9 CDJ69876.1 - 2.7 6.1 5.7 2.6 6.2 4.0 1.0 1 0 0 1 1 1 0 Cellulose synthase Peptidase_U57 PF05582.7 CDJ69876.1 - 3 6.7 11.6 3.1 6.6 8.0 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF2215 PF10225.4 CDJ69876.1 - 3.3 7.1 8.1 4 6.8 5.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Herpes_glycop PF01528.11 CDJ69876.1 - 3.3 6.3 5.3 3.4 6.2 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M HRXXH PF13933.1 CDJ69876.1 - 3.6 6.9 8.3 4.2 6.6 5.7 1.1 1 0 0 1 1 1 0 Putative peptidase family DUF1675 PF07897.6 CDJ69876.1 - 3.7 7.3 10.8 3.7 7.3 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF844 PF05815.6 CDJ69876.1 - 3.9 6.2 13.1 4.2 6.1 9.1 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Med15 PF09606.5 CDJ69876.1 - 4 5.5 48.5 4 5.5 33.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EIIBC-GUT_N PF03612.9 CDJ69876.1 - 4.3 6.9 13.0 4.8 6.7 9.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CoA_transf_3 PF02515.12 CDJ69876.1 - 4.4 6.4 10.8 5 6.3 7.5 1.0 1 0 0 1 1 1 0 CoA-transferase family III RR_TM4-6 PF06459.7 CDJ69876.1 - 4.7 7.0 16.1 5 6.9 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FliP PF00813.15 CDJ69876.1 - 4.7 6.8 5.9 5.2 6.7 4.1 1.1 1 0 0 1 1 1 0 FliP family Anoctamin PF04547.7 CDJ69876.1 - 5.2 5.5 7.2 5 5.6 5.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel FixO PF02433.10 CDJ69876.1 - 5.6 6.2 8.7 5.9 6.1 6.1 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Ndc1_Nup PF09531.5 CDJ69876.1 - 5.6 5.2 12.1 5.5 5.2 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hom_end_hint PF05203.11 CDJ69876.1 - 6 6.5 8.9 6.5 6.4 6.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint TCP PF03634.8 CDJ69876.1 - 6.2 7.1 20.0 6.8 7.0 13.8 1.1 1 0 0 1 1 1 0 TCP family transcription factor FAM60A PF15396.1 CDJ69876.1 - 6.5 6.4 12.1 7.1 6.3 8.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TrbI PF03743.9 CDJ69876.1 - 7 6.0 14.5 8.2 5.8 10.1 1.1 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein LEA_3 PF03242.8 CDJ69876.1 - 7.2 6.9 8.2 14 6.0 5.7 1.6 1 1 0 1 1 1 0 Late embryogenesis abundant protein Spore_coat_CotO PF14153.1 CDJ69876.1 - 7.3 5.9 25.4 8.5 5.7 17.6 1.0 1 0 0 1 1 1 0 Spore coat protein CotO HD-ZIP_N PF04618.7 CDJ69876.1 - 7.5 7.1 9.3 8.9 6.8 6.5 1.1 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF106 PF01956.11 CDJ69876.1 - 7.6 6.0 11.5 7.8 6.0 8.0 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3408 PF11888.3 CDJ69876.1 - 8 6.3 15.6 9.9 6.0 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) PAT1 PF09770.4 CDJ69876.1 - 8.2 4.5 37.2 8.6 4.4 25.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1764 PF08576.5 CDJ69876.1 - 8.3 7.2 19.2 9.5 7.0 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CDC45 PF02724.9 CDJ69876.1 - 9 4.1 15.2 10 3.9 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 CDJ69876.1 - 9.4 4.8 19.2 9.9 4.7 13.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DEAD_assoc PF08494.6 CDJ69878.1 - 0.076 12.7 0.1 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 DEAD/H associated Med3 PF11593.3 CDJ69878.1 - 5.8 6.0 10.0 9.2 5.3 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TrbI PF03743.9 CDJ69878.1 - 9.6 5.6 7.1 22 4.4 3.0 2.1 1 1 1 2 2 2 0 Bacterial conjugation TrbI-like protein CDK2AP PF09806.4 CDJ69879.1 - 6.6 6.9 0.0 6.6 6.9 0.0 9.4 5 4 2 7 7 7 0 Cyclin-dependent kinase 2-associated protein MIP-T3 PF10243.4 CDJ69880.1 - 1.3 7.3 61.6 0.019 13.4 30.2 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 CDJ69880.1 - 3.9 5.5 69.0 0.054 11.7 30.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 CDJ69880.1 - 5 6.2 48.8 2.5 7.2 27.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) HHV6-IE PF03753.8 CDJ69880.1 - 7.8 3.8 23.7 11 3.2 16.5 1.2 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein LisH PF08513.6 CDJ69881.1 - 2.1e-07 30.4 0.3 4.5e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 LisH Dehydrin PF00257.14 CDJ69881.1 - 0.006 16.9 0.1 0.006 16.9 0.1 2.5 2 1 0 2 2 2 1 Dehydrin Spt20 PF12090.3 CDJ69881.1 - 0.052 12.9 1.1 0.076 12.3 0.1 1.8 2 0 0 2 2 2 0 Spt20 family DUF4247 PF14042.1 CDJ69881.1 - 0.11 12.4 2.6 1.7 8.6 1.8 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4247) DUF2140 PF09911.4 CDJ69881.1 - 0.16 11.0 1.2 0.3 10.2 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Pex14_N PF04695.8 CDJ69881.1 - 0.19 11.7 16.8 0.3 11.1 2.9 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4106 PF13388.1 CDJ69881.1 - 0.66 8.8 6.2 0.75 8.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Allexi_40kDa PF05549.6 CDJ69883.1 - 5.6 6.1 11.1 3.7 6.7 0.2 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1168 PF06658.7 CDJ69886.1 - 2.6e-14 52.9 0.2 2.6e-14 52.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Lin-8 PF03353.10 CDJ69886.1 - 0.11 11.7 8.5 0.15 11.3 5.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.4 CDJ69886.1 - 0.21 9.8 28.6 0.27 9.4 19.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4647 PF15504.1 CDJ69886.1 - 0.32 9.7 12.8 0.4 9.4 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Ribosomal_60s PF00428.14 CDJ69886.1 - 0.42 11.0 15.9 0.14 12.5 7.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein SpoIIIAH PF12685.2 CDJ69886.1 - 0.46 9.9 8.2 0.19 11.1 3.9 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein AIF_C PF14721.1 CDJ69886.1 - 1.9 8.7 5.9 3 8.0 1.9 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDJ69886.1 - 2.9 5.4 35.8 5.5 4.5 24.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4355 PF14265.1 CDJ69886.1 - 3.5 7.6 16.6 5.8 6.8 5.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Peptidase_U32 PF01136.14 CDJ69886.1 - 9.3 5.0 9.2 0.67 8.8 0.1 2.1 1 1 1 2 2 2 0 Peptidase family U32 YEATS PF03366.11 CDJ69887.1 - 0.00085 18.9 6.4 5.4 6.8 0.0 6.0 4 2 2 6 6 6 2 YEATS family CS PF04969.11 CDJ69888.1 - 1e-08 35.5 0.1 1.5e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 CS domain DBD_Tnp_Mut PF03108.10 CDJ69888.1 - 0.19 11.3 4.7 0.4 10.2 3.3 1.4 1 0 0 1 1 1 0 MuDR family transposase BNIP2 PF12496.3 CDJ69888.1 - 9.3 6.4 9.0 1.8e+02 2.3 5.6 2.7 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 His_Phos_1 PF00300.17 CDJ69889.1 - 1.8e-17 63.8 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1768 PF08719.6 CDJ69890.1 - 1.2e-14 54.3 0.0 2.8e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.17 CDJ69890.1 - 1.4e-12 47.0 0.0 1e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ69890.1 - 1e-10 41.3 0.0 2.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 CDJ69890.1 - 3e-10 40.0 0.0 8.3e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain RRM_5 PF13893.1 CDJ69890.1 - 2.8e-08 33.5 0.0 8e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L37 PF08561.5 CDJ69892.1 - 3.5e-12 45.6 0.0 5.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF3446 PF11928.3 CDJ69893.1 - 0.4 10.9 31.1 1.4 9.1 7.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) RAB3GAP2_N PF14655.1 CDJ69893.1 - 1.4 7.8 5.2 0.4 9.6 0.8 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1822 PF08852.6 CDJ69895.1 - 0.035 12.9 1.2 0.052 12.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Ebola_NP PF05505.7 CDJ69895.1 - 0.065 11.2 4.9 0.077 11.0 3.4 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Tox-MPTase2 PF15638.1 CDJ69895.1 - 0.14 11.7 0.3 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Macoilin PF09726.4 CDJ69895.1 - 0.64 8.2 21.4 0.89 7.7 14.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 CDJ69895.1 - 4.9 6.2 13.1 8.9 5.4 9.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ndc1_Nup PF09531.5 CDJ69895.1 - 6.7 4.9 8.6 9.6 4.4 6.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAP65_ASE1 PF03999.7 CDJ69895.1 - 7.8 4.9 12.1 11 4.4 8.4 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NAD_binding_11 PF14833.1 CDJ69896.1 - 1.9e-31 108.6 0.0 3.6e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 CDJ69896.1 - 7.4e-19 68.1 0.0 3.8e-09 36.5 0.0 2.4 1 1 1 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CDJ69896.1 - 0.0014 18.9 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Cadherin_2 PF08266.7 CDJ69896.1 - 0.1 12.1 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Cadherin-like Ran_BP1 PF00638.13 CDJ69897.1 - 2.1e-30 105.2 5.2 2.7e-20 72.6 0.5 2.8 3 0 0 3 3 3 2 RanBP1 domain Glyco_trans_2_3 PF13632.1 CDJ69897.1 - 0.0052 16.5 0.9 0.0084 15.8 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF4396 PF14342.1 CDJ69897.1 - 0.019 15.0 5.7 0.029 14.4 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) Binary_toxB PF03495.9 CDJ69898.1 - 0.04 12.5 5.7 0.056 12.0 4.0 1.1 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA DUF3439 PF11921.3 CDJ69898.1 - 0.44 10.3 6.5 0.81 9.4 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pex14_N PF04695.8 CDJ69898.1 - 0.68 9.9 8.7 0.3 11.1 1.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dynein_heavy PF03028.10 CDJ69899.1 - 1.7e-144 482.5 0.0 2.7e-144 481.9 0.0 1.3 1 1 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_7 PF12775.2 CDJ69900.1 - 1.3e-21 76.9 0.0 2.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDJ69900.1 - 1.1e-06 28.4 0.0 0.027 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CDJ69900.1 - 0.014 15.5 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.2 CDJ69901.1 - 7.4e-96 320.1 0.1 1.3e-95 319.2 0.1 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CDJ69901.1 - 8.2e-86 288.0 17.7 8.3e-86 288.0 9.8 3.0 1 1 1 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 CDJ69901.1 - 5.8e-09 35.8 0.0 7.1e-06 25.7 0.0 3.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CDJ69901.1 - 0.0001 22.5 0.6 1.4 9.1 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 CDJ69901.1 - 0.00053 20.1 2.2 0.088 13.0 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CDJ69901.1 - 0.00072 19.1 1.8 0.46 10.0 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CDJ69901.1 - 0.00075 19.6 0.5 1.2 9.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDJ69901.1 - 0.00094 18.8 2.4 0.2 11.4 0.2 2.6 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CDJ69901.1 - 0.0017 17.8 0.2 0.074 12.5 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 CDJ69901.1 - 0.0024 16.5 3.0 0.013 14.1 0.2 3.0 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 CDJ69901.1 - 0.0064 16.4 0.0 1.7 8.5 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain DUF853 PF05872.7 CDJ69901.1 - 0.0068 14.8 3.6 0.18 10.1 0.1 2.3 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) RNA_helicase PF00910.17 CDJ69901.1 - 0.0074 16.4 0.2 1.7 8.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase Zeta_toxin PF06414.7 CDJ69901.1 - 0.02 14.0 0.3 3.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 CDJ69901.1 - 0.027 13.3 0.3 0.19 10.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF258 PF03193.11 CDJ69901.1 - 0.03 13.5 0.1 0.24 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 CDJ69901.1 - 0.043 13.4 1.0 11 5.6 0.0 4.0 4 0 0 4 4 4 0 NACHT domain BCL_N PF04714.8 CDJ69901.1 - 0.058 12.9 0.6 0.35 10.4 0.1 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region AAA_28 PF13521.1 CDJ69901.1 - 0.085 12.8 6.4 1.1 9.1 0.1 3.3 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 CDJ69901.1 - 0.089 12.2 2.0 3 7.2 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.9 CDJ69901.1 - 0.11 12.2 1.9 5.4 6.7 0.1 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RHH_4 PF13467.1 CDJ69901.1 - 0.11 12.3 3.4 3.1 7.7 0.1 3.8 3 1 0 3 3 3 0 Ribbon-helix-helix domain PhoH PF02562.11 CDJ69901.1 - 0.15 11.2 2.2 1.5 8.0 0.1 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 CDJ69901.1 - 0.27 10.6 1.7 22 4.3 0.1 3.5 4 0 0 4 4 4 0 AAA domain ResIII PF04851.10 CDJ69901.1 - 0.43 10.3 3.4 0.83 9.4 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 CDJ69901.1 - 1.7 9.4 0.0 1.7 9.4 0.0 4.3 5 1 0 5 5 4 0 AAA domain DUF3250 PF11618.3 CDJ69902.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3250) EthD PF07110.6 CDJ69902.1 - 0.12 13.2 0.2 0.28 12.1 0.1 1.7 1 1 0 1 1 1 0 EthD domain DHC_N1 PF08385.7 CDJ69903.1 - 5.8e-36 124.0 11.6 5.4e-29 101.0 3.7 2.1 1 1 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 WD40 PF00400.27 CDJ69904.1 - 7.3e-19 66.8 3.5 1.1e-05 25.0 0.6 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat tRNA-synt_2b PF00587.20 CDJ69905.1 - 8.1e-25 87.3 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CDJ69905.1 - 3.1e-06 27.0 0.1 6.5e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain Uma2 PF05685.7 CDJ69905.1 - 0.027 13.8 0.1 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative restriction endonuclease AMP-binding PF00501.23 CDJ69906.1 - 0.0002 19.8 0.0 0.00034 19.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CDJ69907.1 - 3.3e-11 42.2 0.1 5.1e-05 21.8 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme Profilin PF00235.14 CDJ69909.1 - 8.3e-08 32.3 0.0 9.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Profilin Ribosomal_60s PF00428.14 CDJ69910.1 - 7.6 7.0 20.4 11 6.4 14.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Daxx PF03344.10 CDJ69911.1 - 0.34 9.3 25.3 0.39 9.1 17.6 1.0 1 0 0 1 1 1 0 Daxx Family UPF0227 PF05728.7 CDJ69912.1 - 0.048 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2051 PF09738.4 CDJ69912.1 - 4.8 6.3 10.6 9.6 5.3 7.4 1.4 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) CRIC_ras_sig PF10534.4 CDJ69913.1 - 0.013 15.5 1.9 0.021 14.8 0.5 2.0 1 1 0 1 1 1 0 Connector enhancer of kinase suppressor of ras HSP70 PF00012.15 CDJ69913.1 - 0.14 10.0 6.8 0.018 12.9 1.3 1.7 1 1 1 2 2 2 0 Hsp70 protein DUF615 PF04751.9 CDJ69913.1 - 2.1 7.9 12.0 4.1 7.0 8.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF615) TFIIA PF03153.8 CDJ69913.1 - 3.7 7.3 9.6 4.5 7.0 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 CDJ69914.1 - 1.2 9.4 26.8 1.5 9.1 18.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S46 PF10459.4 CDJ69914.1 - 2.5 6.4 21.5 3.4 5.9 14.9 1.2 1 0 0 1 1 1 0 Peptidase S46 SR-25 PF10500.4 CDJ69914.1 - 2.6 7.4 53.9 6.2 6.2 17.6 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF936 PF06075.7 CDJ69914.1 - 4.7 6.0 29.7 6 5.6 20.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PAT1 PF09770.4 CDJ69914.1 - 5.7 5.0 48.0 6.8 4.7 33.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SoxE PF06525.6 CDJ69916.1 - 0.03 13.5 0.2 0.036 13.3 0.1 1.0 1 0 0 1 1 1 0 Sulfocyanin (SoxE) SR-25 PF10500.4 CDJ69916.1 - 0.27 10.6 10.6 0.37 10.2 7.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ69916.1 - 3.3 7.8 11.2 6.2 6.9 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) zf-rbx1 PF12678.2 CDJ69918.1 - 2.7e-16 59.4 4.1 3.6e-16 59.0 2.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CDJ69918.1 - 2.8e-05 23.8 1.5 3.9e-05 23.3 1.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF508 PF04370.7 CDJ69918.1 - 0.063 12.9 7.0 0.083 12.5 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Corona_nucleoca PF00937.13 CDJ69918.1 - 0.59 9.0 8.3 0.64 8.9 5.8 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DNA_pol_viral_N PF00242.12 CDJ69918.1 - 0.76 8.7 11.0 0.16 10.9 5.7 1.3 1 1 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SSP160 PF06933.6 CDJ69918.1 - 3.7 5.4 13.5 3.8 5.3 9.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BSP_II PF05432.6 CDJ69919.1 - 0.021 14.0 6.4 0.031 13.5 4.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Plasmodium_Vir PF05795.6 CDJ69919.1 - 0.066 12.4 0.5 0.095 11.8 0.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GFRP PF06399.8 CDJ69919.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) BTV_NS2 PF04514.7 CDJ69919.1 - 0.15 10.9 10.4 0.23 10.2 7.2 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM176 PF14851.1 CDJ69919.1 - 0.47 10.1 7.0 0.22 11.2 2.8 1.9 2 0 0 2 2 2 0 FAM176 family Spb1_C PF07780.7 CDJ69919.1 - 0.87 9.0 15.5 0.065 12.7 1.5 2.5 2 0 0 2 2 2 0 Spb1 C-terminal domain TT_ORF2 PF02957.10 CDJ69919.1 - 4.3 8.0 9.4 1.5 9.5 4.0 2.0 2 0 0 2 2 2 0 TT viral ORF2 RNA_pol_3_Rpc31 PF11705.3 CDJ69919.1 - 7.4 6.4 21.5 13 5.6 14.3 1.8 1 1 1 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ctf8 PF09696.5 CDJ69920.1 - 0.24 11.1 8.3 0.41 10.4 5.8 1.5 1 1 0 1 1 1 0 Ctf8 F-protein PF00469.15 CDJ69920.1 - 2.4 7.4 11.7 2.6 7.3 8.1 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PRP1_N PF06424.7 CDJ69920.1 - 2.7 8.3 10.5 3.2 8.0 7.3 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DARPP-32 PF05395.7 CDJ69920.1 - 4.4 7.4 22.4 4.7 7.3 15.5 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF3464 PF11947.3 CDJ69920.1 - 7 6.1 9.4 8.4 5.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Baculo_PP31 PF05311.6 CDJ69920.1 - 7.3 5.7 10.7 8 5.6 7.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CPSF100_C PF13299.1 CDJ69920.1 - 7.7 6.6 10.2 9.4 6.3 7.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF243 PF03103.12 CDJ69920.1 - 8.4 6.5 13.9 12 6.1 9.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF243) DUF3801 PF12687.2 CDJ69922.1 - 2.8 7.4 10.0 26 4.2 1.4 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3801) PAN_4 PF14295.1 CDJ69924.1 - 2.1e-08 33.7 0.7 0.00092 18.8 0.0 2.6 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.21 CDJ69924.1 - 6.2e-07 29.0 6.7 0.0021 17.7 0.0 3.2 3 0 0 3 3 3 2 PAN domain DUF2301 PF10063.4 CDJ69925.1 - 0.63 10.2 4.7 0.97 9.6 3.3 1.3 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) MS_channel PF00924.13 CDJ69926.1 - 3.9e-12 45.9 2.4 5.9e-12 45.3 1.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_8 PF13833.1 CDJ69926.1 - 0.098 12.2 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair UPF0546 PF10639.4 CDJ69927.1 - 2.6e-15 56.2 0.5 5.2e-15 55.2 0.3 1.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 DUF2722 PF10846.3 CDJ69927.1 - 0.0013 17.8 3.6 0.0013 17.8 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.3 CDJ69927.1 - 0.0027 17.1 2.4 0.003 16.9 1.7 1.1 1 0 0 1 1 1 1 Spt20 family DivIC PF04977.10 CDJ69927.1 - 0.0039 16.6 7.8 0.0039 16.6 5.4 1.5 2 0 0 2 2 2 1 Septum formation initiator Pex14_N PF04695.8 CDJ69927.1 - 0.0093 16.0 1.5 0.01 15.9 1.1 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDJ69927.1 - 0.012 15.3 3.4 0.013 15.2 2.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dala_Dala_lig_N PF01820.16 CDJ69927.1 - 0.02 15.1 0.0 0.025 14.8 0.0 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF912 PF06024.7 CDJ69927.1 - 0.024 14.6 0.1 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PEX11 PF05648.9 CDJ69927.1 - 0.044 13.0 0.3 0.048 12.9 0.2 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4094 PF13334.1 CDJ69927.1 - 0.046 14.0 1.1 0.072 13.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) FimP PF09766.4 CDJ69927.1 - 0.063 12.3 10.0 0.074 12.1 6.9 1.0 1 0 0 1 1 1 0 Fms-interacting protein Zn_peptidase PF04228.8 CDJ69927.1 - 0.087 12.0 2.1 0.098 11.8 1.4 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase WBP-1 PF11669.3 CDJ69927.1 - 0.11 12.6 0.7 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 OATP PF03137.15 CDJ69927.1 - 0.11 10.5 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RAB3GAP2_N PF14655.1 CDJ69927.1 - 0.14 11.1 3.9 0.15 11.0 2.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SGT1 PF07093.6 CDJ69927.1 - 0.17 10.1 3.7 0.18 10.1 2.6 1.0 1 0 0 1 1 1 0 SGT1 protein DUF4199 PF13858.1 CDJ69927.1 - 0.67 9.8 3.0 0.84 9.5 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Med15 PF09606.5 CDJ69927.1 - 0.83 7.7 21.1 0.96 7.5 14.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 CDJ69927.1 - 1.1 9.3 3.4 1.2 9.1 2.4 1.3 1 1 0 1 1 1 0 Ctr copper transporter family DUF788 PF05620.6 CDJ69927.1 - 1.5 8.6 9.2 0.09 12.6 2.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF788) dsDNA_bind PF01984.15 CDJ69927.1 - 1.9 8.5 18.5 2.4 8.2 12.8 1.1 1 0 0 1 1 1 0 Double-stranded DNA-binding domain PAT1 PF09770.4 CDJ69927.1 - 2.6 6.2 15.4 2.9 6.0 10.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDJ69927.1 - 2.6 7.8 10.5 3.1 7.5 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) APC_CDC26 PF10471.4 CDJ69927.1 - 3.1 8.5 17.8 4.5 8.0 12.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF4175 PF13779.1 CDJ69927.1 - 3.7 5.1 19.7 4.4 4.8 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Activator_LAG-3 PF11498.3 CDJ69927.1 - 3.8 6.1 27.9 4.7 5.8 19.4 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ATP-synt_E PF05680.7 CDJ69927.1 - 4.5 7.3 7.5 1.4 8.8 3.5 1.5 1 1 1 2 2 1 0 ATP synthase E chain Med3 PF11593.3 CDJ69927.1 - 9.5 5.3 17.7 12 5.0 12.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal tRNA_edit PF04073.10 CDJ69928.1 - 8.1e-05 22.4 4.4 0.0014 18.4 0.3 3.0 1 1 1 2 2 2 1 Aminoacyl-tRNA editing domain Trypan_glycop PF00913.14 CDJ69928.1 - 1.6 7.5 22.1 2.2 7.0 15.3 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Citrate_synt PF00285.16 CDJ69929.1 - 1.3e-57 195.2 0.0 2.7e-36 125.0 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase SR-25 PF10500.4 CDJ69930.1 - 0.00015 21.2 3.8 0.00015 21.2 2.7 4.1 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Anoctamin PF04547.7 CDJ69930.1 - 3.3 6.2 12.2 2.1 6.9 3.5 2.2 2 0 0 2 2 2 0 Calcium-activated chloride channel Raftlin PF15250.1 CDJ69930.1 - 5.3 5.4 26.9 0.59 8.6 5.5 2.8 3 0 0 3 3 3 0 Raftlin His_Phos_1 PF00300.17 CDJ69931.1 - 1.4e-08 34.9 2.1 0.00078 19.5 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) BAF1_ABF1 PF04684.8 CDJ69931.1 - 0.0016 17.4 9.3 0.0022 16.9 6.5 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDJ69931.1 - 0.0016 18.6 9.8 0.0018 18.5 6.8 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Med15 PF09606.5 CDJ69931.1 - 0.023 12.9 15.7 0.027 12.6 10.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF305 PF03713.8 CDJ69931.1 - 0.074 12.8 8.4 0.081 12.7 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Activator_LAG-3 PF11498.3 CDJ69931.1 - 0.24 10.1 16.6 0.29 9.8 11.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAT1 PF09770.4 CDJ69931.1 - 0.32 9.1 9.0 0.31 9.2 6.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_capsid PF06112.6 CDJ69931.1 - 0.88 9.5 8.3 1.1 9.2 5.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4557 PF15101.1 CDJ69931.1 - 1.1 9.0 4.7 1.6 8.5 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AIRC PF00731.15 CDJ69931.1 - 1.3 8.2 7.3 3.6 6.8 0.1 2.1 2 0 0 2 2 2 0 AIR carboxylase DUF2489 PF10675.4 CDJ69931.1 - 6.5 6.4 10.1 10 5.7 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Tho2 PF11262.3 CDJ69933.1 - 1.3e-62 211.5 1.7 8.1e-47 159.6 0.0 2.6 2 1 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 ABC2_membrane PF01061.19 CDJ69935.1 - 1e-33 116.2 20.9 1.5e-33 115.7 14.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CDJ69935.1 - 8.5e-23 81.1 2.6 1.6e-20 73.8 0.1 3.2 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CDJ69935.1 - 6e-10 39.5 0.0 0.00045 20.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 CDJ69935.1 - 1.4e-05 24.2 16.7 1.4e-05 24.2 11.6 2.4 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.1 CDJ69935.1 - 0.00014 21.8 0.0 0.00014 21.8 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF258 PF03193.11 CDJ69935.1 - 0.00015 20.9 0.2 0.00029 20.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDJ69935.1 - 0.00028 21.0 0.1 0.0015 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CDJ69935.1 - 0.00042 19.7 0.5 0.0051 16.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CDJ69935.1 - 0.00052 18.9 0.0 0.00087 18.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 CDJ69935.1 - 0.00071 19.0 0.1 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CDJ69935.1 - 0.0009 20.0 0.0 0.0018 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CDJ69935.1 - 0.0019 18.5 2.4 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CDJ69935.1 - 0.0027 17.1 0.2 0.0044 16.4 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CDJ69935.1 - 0.0029 17.3 0.2 0.0077 15.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CDJ69935.1 - 0.0034 17.6 0.4 0.0067 16.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain ATP-synt_ab PF00006.20 CDJ69935.1 - 0.0054 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 CDJ69935.1 - 0.0054 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase SMC_N PF02463.14 CDJ69935.1 - 0.0064 15.7 0.1 0.87 8.7 0.1 2.5 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 CDJ69935.1 - 0.0085 16.2 0.0 0.026 14.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CDJ69935.1 - 0.01 15.8 0.2 0.01 15.8 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 CDJ69935.1 - 0.015 15.1 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain Miro PF08477.8 CDJ69935.1 - 0.02 15.3 0.2 0.05 14.1 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein NACHT PF05729.7 CDJ69935.1 - 0.022 14.4 0.1 0.065 12.8 0.1 1.8 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 CDJ69935.1 - 0.024 14.5 0.3 0.046 13.6 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 CDJ69935.1 - 0.032 14.1 0.0 0.085 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CDJ69935.1 - 0.033 13.6 1.7 0.1 12.0 0.6 2.1 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 CDJ69935.1 - 0.041 13.3 0.7 0.14 11.6 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 CDJ69935.1 - 0.055 12.8 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.9 CDJ69935.1 - 0.062 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 CDJ69935.1 - 0.067 12.2 0.0 1.5 7.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 CDJ69935.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CDJ69935.1 - 0.076 12.5 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CDJ69935.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 CDJ69935.1 - 0.12 12.3 0.3 0.99 9.3 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Guanylate_kin PF00625.16 CDJ69935.1 - 0.13 11.6 0.1 0.33 10.3 0.1 1.6 1 0 0 1 1 1 0 Guanylate kinase NTPase_1 PF03266.10 CDJ69935.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 NTPase Rad17 PF03215.10 CDJ69935.1 - 0.18 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SRPRB PF09439.5 CDJ69935.1 - 0.21 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 CDJ69935.1 - 0.23 10.4 0.0 0.45 9.4 0.0 1.4 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.18 CDJ69935.1 - 0.87 9.3 4.0 0.51 10.1 0.2 2.1 2 0 0 2 2 2 0 Dynamin family TRAPPC10 PF12584.3 CDJ69936.1 - 1.9e-05 24.2 0.4 0.00012 21.5 0.0 2.5 3 0 0 3 3 3 1 Trafficking protein particle complex subunit 10, TRAPPC10 DnaJ-X PF14308.1 CDJ69937.1 - 0.27 10.4 5.0 0.19 10.9 2.6 1.4 1 1 0 1 1 1 0 X-domain of DnaJ-containing Snf7 PF03357.16 CDJ69937.1 - 0.75 9.1 5.9 0.97 8.7 4.1 1.1 1 0 0 1 1 1 0 Snf7 DUF1771 PF08590.5 CDJ69937.1 - 1.3 9.1 14.8 2 8.5 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Ribosomal_L30_N PF08079.7 CDJ69937.1 - 6 6.9 19.4 7.3 6.6 12.0 1.9 1 1 1 2 2 2 0 Ribosomal L30 N-terminal domain TRM PF02005.11 CDJ69938.1 - 3.5e-89 299.3 0.0 6.2e-39 133.9 0.3 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 CDJ69938.1 - 0.00058 19.8 2.0 0.0027 17.7 1.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Imm1 PF14430.1 CDJ69938.1 - 0.047 13.8 0.3 0.086 13.0 0.2 1.3 1 0 0 1 1 1 0 Immunity protein Imm1 PrmA PF06325.8 CDJ69938.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-IS66 PF13005.2 CDJ69938.1 - 0.85 9.6 3.3 7.3 6.6 0.3 2.6 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Tau95 PF09734.4 CDJ69940.1 - 2.4e-44 151.9 0.5 1.5e-42 146.0 0.4 2.3 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit GDI PF00996.13 CDJ69941.1 - 1.1e-22 80.0 0.0 3.4e-09 35.5 0.0 4.3 4 0 0 4 4 4 4 GDP dissociation inhibitor SprA-related PF12118.3 CDJ69942.1 - 0.012 14.9 22.0 0.015 14.6 15.3 1.2 1 0 0 1 1 1 0 SprA-related family GOLD_2 PF13897.1 CDJ69942.1 - 0.21 11.8 3.7 0.3 11.3 2.6 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Med15 PF09606.5 CDJ69942.1 - 0.26 9.4 29.3 0.27 9.3 20.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GPCR_chapero_1 PF11904.3 CDJ69942.1 - 2.2 7.3 11.6 2.8 6.9 8.0 1.2 1 0 0 1 1 1 0 GPCR-chaperone PAT1 PF09770.4 CDJ69942.1 - 3.6 5.6 25.4 3.6 5.7 17.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3675 PF12428.3 CDJ69942.1 - 5 7.4 7.7 4.1 7.6 4.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) RR_TM4-6 PF06459.7 CDJ69942.1 - 9.3 6.0 14.1 13 5.6 9.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMEM240 PF15207.1 CDJ69943.1 - 0.091 12.3 0.3 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 TMEM240 family Ank_2 PF12796.2 CDJ69944.1 - 1.3e-22 79.9 1.2 3.2e-12 46.6 0.0 4.9 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ69944.1 - 4.2e-18 64.1 8.6 4.1e-07 29.4 0.3 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 CDJ69944.1 - 1.8e-14 52.3 5.2 0.00013 21.8 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 CDJ69944.1 - 2.3e-12 47.0 1.2 9.3e-07 29.1 0.0 4.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDJ69944.1 - 8.9e-11 41.6 5.6 7.3e-06 26.0 0.4 5.2 3 1 1 5 5 5 2 Ankyrin repeats (many copies) SET PF00856.23 CDJ69944.1 - 0.076 13.3 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 SET domain AAA PF00004.24 CDJ69946.1 - 1.8e-40 138.2 0.0 4.4e-40 136.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDJ69946.1 - 3.5e-06 26.7 0.1 1.7e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDJ69946.1 - 2e-05 24.6 0.2 0.0017 18.3 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CDJ69946.1 - 4.2e-05 22.6 0.0 0.00017 20.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CDJ69946.1 - 0.00026 21.1 0.4 0.021 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 CDJ69946.1 - 0.0004 20.3 0.0 0.0017 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CDJ69946.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CDJ69946.1 - 0.0024 17.0 0.3 0.0093 15.1 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CDJ69946.1 - 0.0048 17.6 0.3 0.02 15.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDJ69946.1 - 0.0056 15.7 0.1 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 CDJ69946.1 - 0.015 15.0 0.2 0.039 13.6 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 CDJ69946.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CDJ69946.1 - 0.024 14.5 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CDJ69946.1 - 0.028 13.6 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 CDJ69946.1 - 0.03 13.7 0.4 0.21 10.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain KaiC PF06745.8 CDJ69946.1 - 0.033 13.3 0.1 0.33 10.0 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF1640 PF07798.6 CDJ69946.1 - 0.033 14.2 0.1 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF815 PF05673.8 CDJ69946.1 - 0.033 13.1 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 CDJ69946.1 - 0.041 13.5 0.2 0.77 9.4 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.1 CDJ69946.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 CDJ69946.1 - 0.073 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF904 PF06005.7 CDJ69946.1 - 0.12 12.6 2.0 0.31 11.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Retrotrans_gag PF03732.12 CDJ69948.1 - 0.0055 16.7 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DnaJ_CXXCXGXG PF00684.14 CDJ69948.1 - 0.063 13.3 8.4 0.18 11.8 5.8 1.7 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC PF00098.18 CDJ69948.1 - 0.13 12.2 11.2 0.44 10.5 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ69948.1 - 1.1 9.1 6.9 0.32 10.7 0.6 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ69948.1 - 2.9 7.6 5.8 14 5.4 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ69948.1 - 5.2 6.8 8.8 1.1 8.9 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle Asp_protease_2 PF13650.1 CDJ69949.1 - 1.2e-08 35.3 0.0 2.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CDJ69949.1 - 8.1e-07 28.6 0.0 1.7e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CDJ69949.1 - 9.5e-06 25.3 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ69949.1 - 1.4e-05 24.9 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ69949.1 - 9.2e-05 22.3 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ69949.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 CDJ69949.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Spt20 PF12090.3 CDJ69950.1 - 0.25 10.6 12.1 0.26 10.6 2.0 2.3 2 0 0 2 2 2 0 Spt20 family DUF1764 PF08576.5 CDJ69950.1 - 0.54 11.0 11.6 0.93 10.2 0.4 3.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) FimP PF09766.4 CDJ69950.1 - 1.2 8.1 14.4 0.061 12.3 3.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein SR-25 PF10500.4 CDJ69952.1 - 0.27 10.6 31.9 0.46 9.9 22.1 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 CDJ69952.1 - 9.7 5.8 31.4 12 5.4 21.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF788 PF05620.6 CDJ69953.1 - 0.0039 17.0 5.0 0.0039 17.0 3.4 5.2 3 1 2 5 5 5 1 Protein of unknown function (DUF788) DUF4492 PF14899.1 CDJ69953.1 - 1.2 8.7 0.0 1.2 8.7 0.0 3.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4492) Neur_chan_memb PF02932.11 CDJ69953.1 - 2.7 7.8 36.7 0.034 14.0 17.0 2.7 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region E1_dh PF00676.15 CDJ69954.1 - 9.6e-64 214.9 0.0 1.1e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 CDJ69954.1 - 0.001 17.9 0.2 0.0015 17.4 0.1 1.3 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CDJ69954.1 - 0.1 11.5 0.1 0.25 10.2 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DUF1049 PF06305.6 CDJ69956.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1049) DUF913 PF06025.7 CDJ69956.1 - 0.17 10.5 5.9 0.44 9.2 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Kei1 PF08552.6 CDJ69956.1 - 0.25 10.9 20.4 0.036 13.7 0.7 3.6 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 UPF0542 PF15086.1 CDJ69956.1 - 0.26 11.0 0.0 0.26 11.0 0.0 3.3 4 0 0 4 4 4 0 Uncharacterised protein family UPF0542 Claudin_2 PF13903.1 CDJ69956.1 - 0.28 10.8 0.0 0.28 10.8 0.0 3.9 4 1 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction DUF3801 PF12687.2 CDJ69956.1 - 2.7 7.5 16.3 0.23 11.0 4.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3801) Band_3_cyto PF07565.8 CDJ69956.1 - 3 7.2 16.9 2.8 7.4 1.2 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain DUF1510 PF07423.6 CDJ69956.1 - 3.8 6.8 14.9 0.13 11.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DEC-1_N PF04625.8 CDJ69957.1 - 0.78 8.3 8.2 0.96 8.0 5.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.14 CDJ69957.1 - 1.5 9.2 15.8 5 7.5 11.0 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein PNP_UDP_1 PF01048.15 CDJ69961.1 - 1.5e-20 73.1 0.0 1.7e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily PTCRA PF15028.1 CDJ69963.1 - 0.076 12.5 1.9 0.21 11.1 1.3 1.8 1 0 0 1 1 1 0 Pre-T-cell antigen receptor SR-25 PF10500.4 CDJ69964.1 - 7.6e-05 22.2 15.2 7.6e-05 22.2 10.6 3.3 2 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.2 CDJ69964.1 - 6.6 6.3 21.3 4.2 6.9 2.7 2.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit LMBR1 PF04791.11 CDJ69965.1 - 0.0082 14.7 0.0 0.11 11.1 0.0 1.9 1 1 1 2 2 2 1 LMBR1-like membrane protein FAM176 PF14851.1 CDJ69965.1 - 0.11 12.1 13.2 0.67 9.6 0.7 2.2 2 0 0 2 2 2 0 FAM176 family Gti1_Pac2 PF09729.4 CDJ69965.1 - 0.25 11.2 13.5 0.32 10.8 2.7 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Spore_coat_CotO PF14153.1 CDJ69965.1 - 0.99 8.8 25.9 0.21 11.0 11.0 2.4 2 0 0 2 2 2 0 Spore coat protein CotO HlyD_2 PF12700.2 CDJ69966.1 - 5.3 6.1 17.6 1.1 8.3 0.1 2.2 2 0 0 2 2 2 0 HlyD family secretion protein WD40 PF00400.27 CDJ69968.1 - 5.8e-14 51.3 1.1 1.1e-07 31.3 0.2 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Telomere_Sde2_2 PF13297.1 CDJ69969.1 - 6.1e-18 63.8 0.6 1.3e-17 62.8 0.4 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal Telomere_Sde2 PF13019.1 CDJ69969.1 - 2.6e-13 49.9 0.5 2.6e-13 49.9 0.3 2.7 2 2 0 2 2 2 1 Telomere stability and silencing SLBP_RNA_bind PF15247.1 CDJ69971.1 - 5.6e-21 74.1 0.8 5.6e-21 74.1 0.6 1.7 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain TBP PF00352.16 CDJ69973.1 - 9.3e-12 44.1 0.0 2.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) RNA_pol_Rpb2_6 PF00562.23 CDJ69974.1 - 6.2e-123 410.3 0.0 9e-123 409.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CDJ69974.1 - 7.5e-60 201.3 0.0 1.1e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CDJ69974.1 - 5.9e-48 162.8 0.0 1e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CDJ69974.1 - 1.6e-30 105.1 0.1 3.8e-30 103.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 CDJ69974.1 - 5.1e-25 87.0 0.0 1.1e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 CDJ69974.1 - 1e-19 70.0 0.1 2.2e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 CDJ69974.1 - 4.6e-16 58.5 1.4 9.6e-16 57.4 1.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNase_PH PF01138.16 CDJ69975.1 - 3.6e-15 56.4 3.3 1.5e-14 54.4 2.3 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 SCPU PF05229.10 CDJ69975.1 - 0.039 14.0 0.9 0.079 13.0 0.6 1.4 1 0 0 1 1 1 0 Spore Coat Protein U domain WD40 PF00400.27 CDJ69976.1 - 4.4e-05 23.1 3.5 1.5 8.8 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat FUSC_2 PF13515.1 CDJ69977.1 - 1.1e-05 25.3 12.0 1.1e-05 25.3 8.3 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like Nup84_Nup100 PF04121.8 CDJ69978.1 - 0.015 13.0 0.8 0.047 11.3 0.0 2.1 3 0 0 3 3 3 0 Nuclear pore protein 84 / 107 Cuticle_1 PF08140.6 CDJ69978.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Crustacean cuticle protein repeat DUF1942 PF09167.6 CDJ69978.1 - 0.17 11.6 0.8 0.6 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) MMR_HSR1 PF01926.18 CDJ69979.1 - 1.1e-42 144.7 0.0 4.1e-23 81.5 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CDJ69979.1 - 3.9e-21 74.9 0.0 8.2e-12 44.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CDJ69979.1 - 1.6e-20 73.3 0.1 7.3e-10 38.5 0.0 4.2 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 CDJ69979.1 - 7.5e-13 49.0 0.0 5.6e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AIG1 PF04548.11 CDJ69979.1 - 1e-11 44.3 0.0 1.1e-05 24.6 0.0 2.5 2 1 1 3 3 3 2 AIG1 family KH_dom-like PF14714.1 CDJ69979.1 - 1.9e-10 40.5 0.0 3.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Ras PF00071.17 CDJ69979.1 - 2e-06 27.2 0.0 0.1 11.9 0.0 3.9 2 2 0 2 2 2 2 Ras family Dynamin_N PF00350.18 CDJ69979.1 - 3.9e-06 26.7 0.0 0.069 12.9 0.0 3.3 4 0 0 4 4 4 2 Dynamin family ArgK PF03308.11 CDJ69979.1 - 4.7e-05 22.3 0.2 2.1 7.0 0.1 4.3 5 0 0 5 5 5 2 ArgK protein cobW PF02492.14 CDJ69979.1 - 0.00011 21.6 0.1 0.22 10.9 0.1 3.6 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 CDJ69979.1 - 0.00014 21.3 0.1 5.3 6.4 0.0 3.9 4 1 0 4 4 4 1 AAA domain SRPRB PF09439.5 CDJ69979.1 - 0.0028 16.9 0.0 16 4.6 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Arf PF00025.16 CDJ69979.1 - 0.0033 16.6 0.0 1.1 8.5 0.0 3.9 4 1 0 4 4 4 1 ADP-ribosylation factor family DUF258 PF03193.11 CDJ69979.1 - 0.011 14.9 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CDJ69979.1 - 0.012 15.7 0.0 0.43 10.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain Glyco_hydro_3_C PF01915.17 CDJ69979.1 - 0.054 13.0 0.1 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain MCM PF00493.18 CDJ69979.1 - 0.062 12.0 0.0 4 6.1 0.0 2.3 2 0 0 2 2 2 0 MCM2/3/5 family Arch_ATPase PF01637.13 CDJ69979.1 - 0.1 12.2 0.0 18 4.9 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 CDJ69979.1 - 0.13 12.5 0.0 4.2 7.6 0.0 2.6 3 0 0 3 3 2 0 ABC transporter RNA_helicase PF00910.17 CDJ69979.1 - 0.2 11.8 0.0 25 5.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Fcf2 PF08698.6 CDJ69980.1 - 9.6e-08 31.9 1.7 1.4e-06 28.1 1.2 2.4 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing CHZ PF09649.5 CDJ69980.1 - 0.076 12.2 0.1 0.18 11.0 0.1 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ DnaJ PF00226.26 CDJ69983.1 - 5.6e-16 58.0 0.0 1.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Cyt-b5 PF00173.23 CDJ69984.1 - 1e-24 86.1 0.0 1.3e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.24 CDJ69985.1 - 8.2e-39 132.8 0.0 1.8e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDJ69985.1 - 4.9e-24 84.0 0.0 1.2e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EF-hand_8 PF13833.1 CDJ69986.1 - 5.5e-07 29.0 0.3 2.1e-06 27.2 0.2 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CDJ69986.1 - 0.0023 18.0 0.3 0.0039 17.2 0.2 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CDJ69986.1 - 0.0069 16.1 0.6 0.94 9.5 0.1 2.9 1 1 1 2 2 2 1 EF-hand domain DUF3008 PF11450.3 CDJ69986.1 - 0.029 14.5 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) EFhand_Ca_insen PF08726.5 CDJ69986.1 - 0.14 12.1 0.0 2.3 8.2 0.0 2.2 1 1 1 2 2 2 0 Ca2+ insensitive EF hand EF-hand_6 PF13405.1 CDJ69987.1 - 6.1e-08 31.9 0.4 1.6e-07 30.6 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CDJ69987.1 - 8.3e-07 27.8 0.2 3.4e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CDJ69987.1 - 7.4e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CDJ69987.1 - 0.00045 19.4 0.5 0.013 14.7 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.1 CDJ69987.1 - 0.02 14.8 0.0 0.056 13.3 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 CDJ69987.1 - 0.026 14.1 0.1 0.88 9.2 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain pair ThiS PF02597.15 CDJ69987.1 - 0.08 13.3 0.2 0.12 12.8 0.1 1.3 1 1 0 1 1 1 0 ThiS family AIG1 PF04548.11 CDJ69987.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 AIG1 family V-SNARE_C PF12352.3 CDJ69988.1 - 6.2e-11 42.1 1.2 1e-10 41.5 0.8 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CDJ69988.1 - 0.0002 21.4 0.8 0.018 15.2 0.0 2.6 3 0 0 3 3 3 2 Vesicle transport v-SNARE protein N-terminus Mito_carr PF00153.22 CDJ69989.1 - 4.8e-26 90.3 0.3 2.1e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Ribosomal_S8 PF00410.14 CDJ69990.1 - 3.8e-25 88.2 0.0 4.7e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 C2 PF00168.25 CDJ69991.1 - 0.0001 22.0 0.3 0.013 15.3 0.2 2.7 1 1 0 1 1 1 1 C2 domain DUF553 PF04473.7 CDJ69991.1 - 0.54 9.5 0.0 1.1 8.5 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain Methyltransf_28 PF02636.12 CDJ69993.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 CDJ69996.1 - 9e-07 28.7 0.1 1.6e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase GET2 PF08690.5 CDJ69996.1 - 0.019 14.2 0.2 0.019 14.2 0.1 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 PseudoU_synth_2 PF00849.17 CDJ69997.1 - 6.1e-07 29.4 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase Defensin_big PF14862.1 CDJ69997.1 - 0.082 12.9 0.1 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Big defensin RRM_1 PF00076.17 CDJ69998.1 - 8.1e-17 60.6 0.0 1.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ69998.1 - 8.9e-14 51.2 0.0 1.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ69998.1 - 8e-09 35.2 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sas10 PF09368.5 CDJ70000.1 - 2.6e-22 78.7 6.0 2.6e-22 78.7 4.2 2.5 2 1 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CDJ70000.1 - 2.4e-19 69.2 4.2 1e-18 67.2 2.9 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family E1-E2_ATPase PF00122.15 CDJ70002.1 - 8.1e-15 54.4 3.0 1.8e-13 50.0 0.0 3.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CDJ70002.1 - 1.7e-11 44.9 6.0 7.8e-06 26.4 2.3 4.3 3 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDJ70002.1 - 4.1e-10 40.1 0.0 0.00072 19.7 0.0 3.7 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDJ70002.1 - 9.7e-06 25.4 0.0 4.7e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDJ70002.1 - 0.03 13.9 0.1 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Methyltransf_18 PF12847.2 CDJ70003.1 - 0.035 14.6 0.0 0.19 12.3 0.0 2.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ70003.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.7 2 2 0 2 2 2 0 Methyltransferase domain Las1 PF04031.8 CDJ70004.1 - 7.6e-26 90.6 0.1 7.6e-26 90.6 0.0 3.7 3 1 0 3 3 3 1 Las1-like WW PF00397.21 CDJ70005.1 - 3.4e-10 39.6 2.4 5.5e-10 38.9 1.7 1.3 1 0 0 1 1 1 1 WW domain TMEM51 PF15345.1 CDJ70005.1 - 0.0034 17.1 4.8 0.0034 17.1 3.4 3.0 3 0 0 3 3 3 1 Transmembrane protein 51 DUF1510 PF07423.6 CDJ70005.1 - 0.004 16.5 0.0 0.01 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Glyco_hydro_100 PF12899.2 CDJ70005.1 - 0.056 11.8 1.0 0.075 11.4 0.0 1.6 2 0 0 2 2 2 0 Alkaline and neutral invertase DUF3357 PF11837.3 CDJ70005.1 - 0.056 13.2 0.2 0.056 13.2 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3357) Yip1 PF04893.12 CDJ70005.1 - 0.29 10.6 20.7 0.56 9.6 12.1 2.7 2 1 1 3 3 3 0 Yip1 domain Pex2_Pex12 PF04757.9 CDJ70006.1 - 3e-06 26.8 9.5 0.006 16.0 2.8 2.7 2 1 1 3 3 3 2 Pex2 / Pex12 amino terminal region DUF755 PF05501.6 CDJ70006.1 - 0.00019 21.5 13.4 0.00019 21.5 9.3 4.2 3 1 0 3 3 3 1 Domain of unknown function (DUF755) zf-C3HC4_4 PF15227.1 CDJ70006.1 - 0.00021 21.1 11.1 0.00021 21.1 7.7 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CDJ70006.1 - 0.0036 17.1 13.0 0.0036 17.1 9.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDJ70006.1 - 0.007 16.3 11.4 0.007 16.3 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDJ70006.1 - 0.011 15.4 8.2 0.033 13.9 5.7 1.9 1 1 0 1 1 1 0 RING-type zinc-finger SpoIIIAH PF12685.2 CDJ70006.1 - 0.023 14.1 4.8 0.075 12.5 0.2 2.3 2 1 0 2 2 2 0 SpoIIIAH-like protein Sec3_C PF09763.4 CDJ70006.1 - 0.65 8.0 12.1 0.1 10.7 2.0 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 Pex14_N PF04695.8 CDJ70006.1 - 1 9.4 26.7 0.1 12.6 2.7 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.4 CDJ70008.1 - 0.03 13.7 21.3 0.025 14.0 4.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein COG4 PF08318.7 CDJ70008.1 - 0.12 11.0 11.5 0.25 10.0 7.2 1.7 1 1 0 1 1 1 0 COG4 transport protein Serinc PF03348.10 CDJ70008.1 - 1.4 7.5 5.0 1.6 7.3 3.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Herpes_UL3 PF03369.8 CDJ70008.1 - 2.1 8.3 5.7 0.33 10.8 0.6 1.8 1 1 1 2 2 2 0 Herpesvirus UL3 protein TraG-D_C PF12696.2 CDJ70008.1 - 2.8 7.8 7.6 9.5 6.0 0.1 2.1 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Ctr PF04145.10 CDJ70008.1 - 9.6 6.2 7.8 3.5 7.6 2.0 2.0 1 1 1 2 2 2 0 Ctr copper transporter family FAST_1 PF06743.10 CDJ70012.1 - 0.65 9.7 2.9 1.3 8.7 0.1 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Peptidase_M16_C PF05193.16 CDJ70014.1 - 1.3e-27 96.6 0.0 4.4e-11 42.7 0.0 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CDJ70014.1 - 5.3e-14 52.2 0.6 5.6e-12 45.6 0.5 2.8 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) YicC_N PF03755.8 CDJ70014.1 - 0.029 14.3 0.8 0.12 12.3 0.0 2.4 3 0 0 3 3 3 0 YicC-like family, N-terminal region Phytochelatin PF05023.9 CDJ70014.1 - 0.042 12.8 0.0 0.083 11.8 0.0 1.4 1 0 0 1 1 1 0 Phytochelatin synthase ALAD PF00490.16 CDJ70015.1 - 1.3e-137 458.0 0.0 1.5e-137 457.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Nop14 PF04147.7 CDJ70015.1 - 0.009 13.9 6.3 0.012 13.6 4.4 1.1 1 0 0 1 1 1 1 Nop14-like family Ebola_NP PF05505.7 CDJ70015.1 - 0.012 13.7 1.6 0.017 13.2 1.1 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 CDJ70015.1 - 0.76 7.7 6.1 1 7.2 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CDJ70015.1 - 3.4 6.0 11.1 4.8 5.5 7.7 1.1 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 CDJ70015.1 - 7 6.2 7.8 11 5.6 5.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AP2 PF00847.15 CDJ70016.1 - 0.00022 21.3 0.9 0.00088 19.3 0.2 2.2 2 0 0 2 2 2 1 AP2 domain Methyltransf_18 PF12847.2 CDJ70017.1 - 1.9e-12 47.7 0.0 5.8e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDJ70017.1 - 7.1e-10 38.8 0.0 2e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ70017.1 - 1.7e-07 30.9 0.0 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ70017.1 - 6.6e-07 29.7 0.0 2.8e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDJ70017.1 - 9e-07 29.1 0.1 2.7e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ70017.1 - 0.00022 21.2 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ70017.1 - 0.00079 19.8 0.0 0.0023 18.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Corona_nucleoca PF00937.13 CDJ70017.1 - 0.035 13.0 3.7 0.057 12.3 2.5 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MTS PF05175.9 CDJ70017.1 - 0.045 13.1 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Pox_MCEL PF03291.11 CDJ70017.1 - 0.069 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme DUF4592 PF15262.1 CDJ70017.1 - 4.9 7.7 9.8 1.7 9.2 2.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) EF-hand_1 PF00036.27 CDJ70019.1 - 6.5e-05 21.9 0.0 0.00025 20.1 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CDJ70019.1 - 0.0001 22.3 0.1 0.00067 19.7 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CDJ70019.1 - 0.00025 20.6 0.0 0.00087 18.9 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CDJ70019.1 - 0.042 13.2 0.1 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 EF hand DUF3355 PF11835.3 CDJ70020.1 - 0.11 12.3 3.0 0.068 12.9 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3355) PEHE PF15275.1 CDJ70020.1 - 1.3 9.5 6.1 0.18 12.2 0.9 2.1 2 0 0 2 2 2 0 PEHE domain HSP90 PF00183.13 CDJ70022.1 - 2.8e-260 864.2 42.9 3.2e-260 864.0 29.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CDJ70022.1 - 3.9e-12 45.8 0.0 7.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CDJ70022.1 - 1.7e-10 40.6 0.1 1.7e-10 40.6 0.1 2.4 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 CDJ70022.1 - 0.0023 17.7 0.2 0.0096 15.7 0.2 2.1 1 0 0 1 1 1 1 Tumour suppressor protein DUF1510 PF07423.6 CDJ70022.1 - 0.015 14.7 23.6 0.041 13.2 16.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CDJ70022.1 - 0.52 10.1 22.8 0.05 13.5 12.4 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CDJ70022.1 - 0.6 9.0 2.1 0.95 8.3 1.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CDJ70022.1 - 0.91 9.2 14.6 0.09 12.5 6.5 1.9 2 0 0 2 2 2 0 DDHD domain DUF2201_N PF13203.1 CDJ70022.1 - 3 6.9 8.6 5.5 6.0 6.0 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Spt20 PF12090.3 CDJ70024.1 - 0.095 12.0 7.4 8.9 5.6 0.2 4.1 4 0 0 4 4 4 0 Spt20 family Yos1 PF08571.5 CDJ70024.1 - 0.12 12.5 2.2 7.4 6.7 0.2 2.8 2 0 0 2 2 2 0 Yos1-like NUC194 PF08163.7 CDJ70024.1 - 0.51 9.1 0.0 5.3 5.7 0.0 2.2 2 0 0 2 2 2 0 NUC194 domain SR-25 PF10500.4 CDJ70025.1 - 6.9 6.0 9.6 12 5.2 6.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3853 PF12964.2 CDJ70026.1 - 0.0011 18.7 0.2 0.0011 18.7 0.1 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF3853) KASH PF10541.4 CDJ70026.1 - 0.0021 17.8 7.3 0.0021 17.8 5.1 3.2 4 0 0 4 4 4 1 Nuclear envelope localisation domain LMBR1 PF04791.11 CDJ70026.1 - 0.0074 14.9 0.0 0.039 12.5 0.0 2.1 1 1 1 2 2 2 1 LMBR1-like membrane protein Hydrolase PF00702.21 CDJ70026.1 - 0.0096 16.3 0.0 0.0096 16.3 0.0 2.8 5 0 0 5 5 5 1 haloacid dehalogenase-like hydrolase Plasmodium_Vir PF05795.6 CDJ70026.1 - 0.033 13.3 1.5 19 4.3 0.0 2.7 1 1 1 2 2 2 0 Plasmodium vivax Vir protein RNA_pol_Rpc4 PF05132.9 CDJ70026.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.8 2 1 1 3 3 3 0 RNA polymerase III RPC4 Herpes_UL87 PF03043.9 CDJ70026.1 - 9 4.5 6.9 23 3.1 4.8 1.7 1 1 0 1 1 1 0 Herpesvirus UL87 family E1-E2_ATPase PF00122.15 CDJ70027.1 - 1e-13 50.8 0.0 1e-13 50.8 0.0 3.3 4 0 0 4 4 4 2 E1-E2 ATPase Spt20 PF12090.3 CDJ70027.1 - 6.7 6.0 11.9 2.3 7.5 0.4 3.3 4 0 0 4 4 4 0 Spt20 family Spore_coat_CotO PF14153.1 CDJ70028.1 - 0.015 14.7 16.7 0.25 10.7 6.4 2.4 2 0 0 2 2 2 0 Spore coat protein CotO AAA_23 PF13476.1 CDJ70028.1 - 0.11 12.8 14.8 0.13 12.5 2.9 2.3 2 0 0 2 2 2 0 AAA domain SAPS PF04499.10 CDJ70028.1 - 0.16 10.5 11.4 1.2 7.6 6.6 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein zf-DHHC PF01529.15 CDJ70028.1 - 0.31 10.4 4.3 0.89 8.9 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase FLO_LFY PF01698.11 CDJ70028.1 - 0.45 9.2 9.3 0.18 10.6 1.3 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Tim54 PF11711.3 CDJ70028.1 - 0.47 9.0 8.4 1.3 7.5 3.0 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.6 CDJ70028.1 - 1.1 8.4 10.2 2.2 7.3 5.2 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Spore_YhcN_YlaJ PF09580.5 CDJ70028.1 - 1.3 9.1 11.2 0.73 9.9 0.7 2.2 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Neur_chan_memb PF02932.11 CDJ70028.1 - 5.4 6.8 21.5 0.25 11.1 6.1 2.3 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.1 CDJ70028.1 - 5.5 4.5 44.8 0.45 8.1 13.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) eIF-3_zeta PF05091.7 CDJ70028.1 - 5.7 5.4 17.8 0.9 8.0 3.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lung_7-TM_R PF06814.8 CDJ70030.1 - 1.7e-17 63.3 0.4 2.4e-17 62.8 0.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CDJ70030.1 - 0.0014 17.8 0.9 0.0028 16.8 0.6 1.5 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain BMF PF15185.1 CDJ70030.1 - 0.07 12.4 1.0 0.12 11.6 0.7 1.4 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis TSA PF03249.8 CDJ70030.1 - 4 5.8 9.1 6 5.2 6.3 1.2 1 0 0 1 1 1 0 Type specific antigen Bindin PF02084.10 CDJ70030.1 - 4.5 7.2 16.4 1.9 8.4 0.3 2.6 2 0 0 2 2 2 0 Bindin SMN PF06003.7 CDJ70031.1 - 0.42 9.6 10.4 0.6 9.1 7.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) UPF0104 PF03706.8 CDJ70031.1 - 0.74 9.0 10.5 13 4.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) Herpes_pp85 PF04637.7 CDJ70031.1 - 1.6 6.9 12.8 1.8 6.7 8.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SOBP PF15279.1 CDJ70031.1 - 3.2 8.0 17.3 4.4 7.5 12.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2051 PF09738.4 CDJ70031.1 - 3.3 6.9 13.0 4.5 6.4 9.0 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) FAM60A PF15396.1 CDJ70031.1 - 4.1 7.0 8.5 5.1 6.7 5.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF822 PF05687.8 CDJ70031.1 - 4.7 7.5 12.1 7 6.9 8.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Macoilin PF09726.4 CDJ70031.1 - 6.8 4.8 17.2 8.5 4.5 12.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Plasmodium_Vir PF05795.6 CDJ70031.1 - 7.6 5.6 6.0 9.2 5.3 4.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2217 PF10265.4 CDJ70031.1 - 7.7 5.1 15.0 9.5 4.8 10.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DNA_pol_viral_N PF00242.12 CDJ70031.1 - 9.2 5.1 18.8 10 5.0 13.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain FtsJ PF01728.14 CDJ70032.1 - 2.8e-29 102.4 1.1 4.4e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CDJ70032.1 - 5.5e-15 55.2 9.0 3.5e-13 49.3 6.9 7.6 4 3 2 7 7 7 3 Domain of unknown function (DUF3381) OmpH PF03938.9 CDJ70032.1 - 0.00031 20.7 12.9 0.00031 20.7 8.9 6.5 4 1 1 5 5 5 1 Outer membrane protein (OmpH-like) SR-25 PF10500.4 CDJ70032.1 - 0.0037 16.7 15.3 0.0037 16.7 10.6 8.2 5 2 4 9 9 9 2 Nuclear RNA-splicing-associated protein DUF2871 PF11070.3 CDJ70033.1 - 0.1 12.7 1.0 0.14 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) PEN-2 PF10251.4 CDJ70035.1 - 0.00052 20.1 0.5 0.018 15.2 0.0 2.5 1 1 1 2 2 2 1 Presenilin enhancer-2 subunit of gamma secretase DUF4557 PF15101.1 CDJ70035.1 - 0.001 18.9 17.4 0.0014 18.4 12.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) DUF2828 PF11443.3 CDJ70035.1 - 0.0017 16.6 0.1 0.0017 16.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) FLO_LFY PF01698.11 CDJ70035.1 - 0.016 14.0 5.5 0.018 13.9 3.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Med15 PF09606.5 CDJ70035.1 - 0.084 11.0 40.1 0.1 10.7 27.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDJ70035.1 - 0.084 12.7 9.7 0.13 12.1 6.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FHIPEP PF00771.15 CDJ70035.1 - 0.093 11.0 5.2 0.12 10.6 3.6 1.2 1 0 0 1 1 1 0 FHIPEP family Suf PF05843.9 CDJ70035.1 - 0.1 12.3 14.1 0.13 11.9 9.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HemX PF04375.9 CDJ70035.1 - 0.25 9.8 24.3 0.34 9.4 16.8 1.1 1 0 0 1 1 1 0 HemX NARP1 PF12569.3 CDJ70035.1 - 0.26 10.0 11.3 0.31 9.7 7.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cellulose_synt PF03552.9 CDJ70035.1 - 0.36 9.0 1.8 0.47 8.6 1.3 1.2 1 0 0 1 1 1 0 Cellulose synthase AAA_23 PF13476.1 CDJ70035.1 - 0.55 10.5 13.7 0.73 10.1 9.5 1.1 1 0 0 1 1 1 0 AAA domain Inhibitor_I71 PF12628.2 CDJ70035.1 - 0.95 9.0 6.5 1.3 8.6 4.5 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Tim54 PF11711.3 CDJ70035.1 - 1 7.8 9.9 1.4 7.4 6.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S15 PF02129.13 CDJ70035.1 - 1.6 8.1 8.4 2.2 7.6 5.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Dala_Dala_lig_N PF01820.16 CDJ70035.1 - 2.3 8.5 7.5 3.8 7.8 5.2 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Serinc PF03348.10 CDJ70035.1 - 2.3 6.8 14.9 1.4 7.5 6.7 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) DDHD PF02862.12 CDJ70035.1 - 2.3 7.9 11.4 3.2 7.4 7.9 1.1 1 0 0 1 1 1 0 DDHD domain DUF3408 PF11888.3 CDJ70035.1 - 2.9 7.8 13.0 4.1 7.3 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Peptidase_S49_N PF08496.5 CDJ70035.1 - 3.1 7.5 14.7 6.6 6.5 10.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Conotoxin PF02950.12 CDJ70035.1 - 4.1 8.2 13.2 12 6.7 0.0 2.6 2 0 0 2 2 2 0 Conotoxin MDFI PF15316.1 CDJ70035.1 - 4.2 7.3 5.9 5.2 7.0 4.1 1.2 1 0 0 1 1 1 0 MyoD family inhibitor TFIIA PF03153.8 CDJ70035.1 - 7.3 6.3 26.2 9 6.0 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Motile_Sperm PF00635.21 CDJ70036.1 - 2.3e-20 72.2 0.0 3.6e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 CDJ70036.1 - 0.054 13.5 0.1 0.34 11.0 0.0 2.1 1 1 1 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF3450 PF11932.3 CDJ70036.1 - 0.29 10.3 4.0 0.43 9.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MSP1_C PF07462.6 CDJ70036.1 - 0.42 8.9 6.5 0.52 8.6 4.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Peptidase_S8 PF00082.17 CDJ70036.1 - 6 5.9 9.8 12 4.9 6.8 1.5 1 1 0 1 1 1 0 Subtilase family AdoMetDC_leader PF08132.6 CDJ70036.1 - 7.2 6.6 10.7 5 7.1 1.7 2.4 2 0 0 2 2 2 0 S-adenosyl-l-methionine decarboxylase leader peptide Peptidase_M22 PF00814.20 CDJ70037.1 - 8.3e-17 61.5 7.8 8.1e-07 28.7 0.0 5.4 4 1 0 5 5 5 5 Glycoprotease family UPF0564 PF10595.4 CDJ70037.1 - 0.0014 17.6 26.6 0.0014 17.6 18.4 3.4 4 0 0 4 4 4 2 Uncharacterised protein family UPF0564 SAPS PF04499.10 CDJ70037.1 - 0.0066 15.1 14.8 0.049 12.2 6.2 2.9 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein DUF2722 PF10846.3 CDJ70037.1 - 0.2 10.6 0.0 0.2 10.6 0.0 6.3 4 2 2 6 6 6 0 Protein of unknown function (DUF2722) Mem_trans PF03547.13 CDJ70037.1 - 2.6 6.2 4.5 6.7 4.8 3.1 1.7 1 0 0 1 1 1 0 Membrane transport protein Methyltransf_15 PF09445.5 CDJ70038.1 - 9e-06 25.3 0.2 1.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Spt20 PF12090.3 CDJ70038.1 - 0.13 11.6 22.1 1.3 8.3 0.5 4.2 4 0 0 4 4 4 0 Spt20 family DUF2722 PF10846.3 CDJ70038.1 - 0.15 11.0 30.6 0.16 10.9 0.4 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) LAT PF15234.1 CDJ70038.1 - 3.3 7.1 8.8 1.1 8.6 3.4 2.4 2 0 0 2 2 2 0 Linker for activation of T-cells Gastrin PF00918.12 CDJ70038.1 - 7.2 7.4 32.7 0.059 14.1 0.9 4.9 4 0 0 4 4 4 0 Gastrin/cholecystokinin family Mon1 PF03164.9 CDJ70039.1 - 0.16 10.5 0.1 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 ubiquitin PF00240.18 CDJ70040.1 - 5e-20 70.6 0.1 5e-20 70.6 0.0 1.7 2 0 0 2 2 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDJ70040.1 - 3.7e-07 29.7 0.0 3.7e-07 29.7 0.0 1.8 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CDJ70040.1 - 3.9e-05 23.5 1.2 6.8e-05 22.7 0.8 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDJ70040.1 - 9.2e-05 22.5 0.6 0.00014 21.9 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 CDJ70040.1 - 0.011 16.0 0.1 0.011 16.0 0.0 1.7 2 1 0 2 2 1 0 Ubiquitin-like domain Pex14_N PF04695.8 CDJ70040.1 - 0.016 15.2 2.2 0.016 15.2 1.5 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 CDJ70040.1 - 0.043 13.1 1.4 0.049 12.9 1.0 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDJ70040.1 - 0.055 13.1 0.6 0.051 13.2 0.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med13_N PF11597.3 CDJ70040.1 - 0.067 11.8 1.5 0.092 11.4 1.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal YukD PF08817.5 CDJ70040.1 - 0.11 13.0 0.0 0.61 10.6 0.0 2.2 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD RAB3GAP2_N PF14655.1 CDJ70040.1 - 0.51 9.2 4.4 0.68 8.8 3.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3597 PF12200.3 CDJ70040.1 - 0.85 10.0 11.3 2.2 8.6 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) DUF4349 PF14257.1 CDJ70040.1 - 1.1 8.4 11.5 0.29 10.3 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF4139 PF13598.1 CDJ70040.1 - 8.2 5.6 10.0 0.74 9.0 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) V-SNARE PF05008.10 CDJ70041.1 - 0.17 12.0 0.1 0.17 12.0 0.1 4.4 5 0 0 5 5 5 0 Vesicle transport v-SNARE protein N-terminus DUF1664 PF07889.7 CDJ70041.1 - 0.59 9.9 9.1 1.5 8.6 0.1 4.2 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF1396 PF07161.8 CDJ70042.1 - 0.023 14.3 0.0 0.071 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1396) Malic_M PF03949.10 CDJ70042.1 - 0.043 13.3 0.1 0.043 13.3 0.1 2.2 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain MutS_III PF05192.13 CDJ70042.1 - 8.5 6.0 9.5 7e+02 -0.2 6.5 3.2 1 1 0 1 1 1 0 MutS domain III VSG_B PF13206.1 CDJ70042.1 - 9.3 5.2 13.5 0.76 8.8 0.7 2.5 2 0 0 2 2 2 0 Trypanosomal VSG domain Ank_2 PF12796.2 CDJ70043.1 - 1.8e-34 117.9 0.1 7.4e-14 51.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CDJ70043.1 - 7.1e-24 82.3 0.5 3e-06 26.7 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CDJ70043.1 - 4e-19 68.1 0.6 2.6e-08 33.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDJ70043.1 - 2.8e-17 62.7 0.8 4e-09 36.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDJ70043.1 - 1.6e-16 58.7 0.2 0.0012 18.8 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat DUF3446 PF11928.3 CDJ70043.1 - 0.015 15.4 8.3 0.015 15.4 5.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3446) SMN PF06003.7 CDJ70043.1 - 0.19 10.7 2.7 0.37 9.8 1.8 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Myosin_head PF00063.16 CDJ70046.1 - 1.7e-104 350.2 0.2 2.2e-104 349.9 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.1 CDJ70046.1 - 0.0024 18.0 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDJ70046.1 - 0.0029 17.3 0.0 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CDJ70046.1 - 0.005 16.8 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 CDJ70046.1 - 0.01 14.9 0.0 0.029 13.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 CDJ70046.1 - 0.029 13.8 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain CbiA PF01656.18 CDJ70046.1 - 0.033 13.5 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Myosin_N PF02736.14 CDJ70046.1 - 0.069 12.8 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain UPF0079 PF02367.12 CDJ70046.1 - 0.081 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 CDJ70046.1 - 0.091 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 CDJ70046.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 CDJ70046.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CDJ70046.1 - 0.13 11.7 0.1 2.7 7.5 0.0 2.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain PRK PF00485.13 CDJ70046.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 CDJ70046.1 - 0.14 12.9 0.0 0.82 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Actin PF00022.14 CDJ70047.1 - 3.5e-16 58.6 0.0 3.7e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Actin Abhydrolase_5 PF12695.2 CDJ70048.1 - 3e-14 53.0 0.1 3.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDJ70048.1 - 2.5e-12 47.1 2.0 3.1e-12 46.8 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CDJ70048.1 - 7.9e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CDJ70048.1 - 0.00086 18.9 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CDJ70048.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 CDJ70048.1 - 0.0052 16.2 0.0 0.043 13.2 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Peptidase_M16 PF00675.15 CDJ70049.1 - 1.7e-44 151.1 0.5 6.3e-26 90.9 0.1 3.0 2 1 1 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CDJ70049.1 - 8.3e-35 120.1 0.0 1.9e-34 118.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF1464 PF07318.7 CDJ70050.1 - 0.33 9.7 3.5 0.13 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) Cys_Met_Meta_PP PF01053.15 CDJ70052.1 - 1.3e-114 382.4 0.1 1.9e-64 217.3 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CDJ70052.1 - 6.7e-07 28.6 2.1 9.7e-07 28.1 0.1 2.1 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CDJ70052.1 - 3.1e-05 23.0 0.0 6.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 CDJ70052.1 - 0.04 12.2 0.0 0.15 10.3 0.0 1.9 2 0 0 2 2 2 0 Methionine gamma-lyase Adeno_IVa2 PF02456.10 CDJ70053.1 - 0.42 9.1 3.4 0.16 10.6 0.1 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein APC_CDC26 PF10471.4 CDJ70054.1 - 0.11 13.2 6.0 0.12 13.1 4.2 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 FimP PF09766.4 CDJ70054.1 - 0.27 10.2 4.6 0.29 10.1 3.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein PHD_3 PF13922.1 CDJ70054.1 - 0.59 10.4 3.5 0.62 10.3 2.4 1.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Med3 PF11593.3 CDJ70054.1 - 1.2 8.2 9.7 1.2 8.2 6.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2489 PF10675.4 CDJ70054.1 - 2.5 7.7 6.7 2.8 7.6 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Phostensin_N PF13916.1 CDJ70054.1 - 3.5 7.6 5.5 4 7.4 3.8 1.2 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal E_Pc_C PF06752.7 CDJ70054.1 - 6.1 6.2 8.7 5.8 6.3 6.0 1.0 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus CYSTM PF12734.2 CDJ70054.1 - 8.3 6.5 6.8 9.7 6.3 4.7 1.2 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Metallopep PF12044.3 CDJ70055.1 - 0.33 9.3 5.3 0.42 9.0 3.7 1.1 1 0 0 1 1 1 0 Putative peptidase family DUF4613 PF15390.1 CDJ70059.1 - 7.3 4.6 23.6 11 4.0 16.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CTP_transf_2 PF01467.21 CDJ70061.1 - 2.5e-11 43.8 0.0 4.9e-06 26.6 0.1 4.0 2 2 1 4 4 4 2 Cytidylyltransferase CDC45 PF02724.9 CDJ70061.1 - 0.0019 16.3 13.7 0.0019 16.3 9.5 3.2 2 1 0 3 3 3 1 CDC45-like protein Ycf1 PF05758.7 CDJ70061.1 - 0.91 7.1 43.6 0.093 10.4 8.2 2.2 2 0 0 2 2 2 0 Ycf1 HORMA PF02301.13 CDJ70062.1 - 3e-09 36.6 2.3 1e-08 34.8 0.0 2.2 2 0 0 2 2 1 1 HORMA domain DUF4207 PF13904.1 CDJ70062.1 - 0.11 11.9 31.7 0.19 11.0 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Ribosomal_60s PF00428.14 CDJ70062.1 - 0.15 12.5 34.3 0.23 11.8 8.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA_23 PF13476.1 CDJ70062.1 - 0.18 12.1 17.5 0.081 13.2 5.2 2.1 2 0 0 2 2 2 0 AAA domain Neur_chan_memb PF02932.11 CDJ70062.1 - 0.72 9.6 7.5 1.4 8.7 2.9 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4557 PF15101.1 CDJ70062.1 - 1.1 9.1 24.9 1.2 8.9 10.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) YABBY PF04690.8 CDJ70062.1 - 1.6 8.9 10.9 0.36 11.0 3.6 2.1 2 0 0 2 2 2 0 YABBY protein FLO_LFY PF01698.11 CDJ70062.1 - 2.7 6.7 12.6 3.1 6.5 6.7 1.9 2 0 0 2 2 2 0 Floricaula / Leafy protein FliP PF00813.15 CDJ70062.1 - 2.8 7.6 12.4 0.94 9.1 4.7 2.1 2 0 0 2 2 2 0 FliP family PAT1 PF09770.4 CDJ70062.1 - 3.3 5.8 45.9 2.1 6.4 19.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDJ70062.1 - 4.4 7.0 10.0 5 6.8 4.4 2.0 2 0 0 2 2 2 0 DDHD domain Dynamin_N PF00350.18 CDJ70062.1 - 4.7 6.9 9.2 2 8.2 2.7 2.1 2 0 0 2 2 2 0 Dynamin family SGT1 PF07093.6 CDJ70062.1 - 4.9 5.4 20.1 1.2 7.4 9.2 2.0 2 0 0 2 2 2 0 SGT1 protein DUF4446 PF14584.1 CDJ70062.1 - 7.3 6.4 9.8 2.3 8.0 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Peptidase_S49_N PF08496.5 CDJ70062.1 - 7.9 6.2 12.2 9.5 5.9 5.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FAM177 PF14774.1 CDJ70062.1 - 7.9 6.4 15.2 1 9.2 6.2 2.0 2 0 0 2 2 2 0 FAM177 family BTV_NS2 PF04514.7 CDJ70062.1 - 9.5 4.9 12.7 4.9 5.9 6.1 1.9 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 APC_CDC26 PF10471.4 CDJ70063.1 - 0.084 13.6 11.0 0.27 11.9 2.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF1635 PF07795.6 CDJ70063.1 - 1 8.7 6.6 1.6 8.0 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF566 PF04484.7 CDJ70063.1 - 2.1 7.7 14.8 2.6 7.4 10.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) PHD_3 PF13922.1 CDJ70063.1 - 4.4 7.6 6.9 3.6 7.8 1.0 2.2 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx CDK2AP PF09806.4 CDJ70063.1 - 5.7 7.1 27.8 10 6.2 19.2 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Tctex-1 PF03645.8 CDJ70064.1 - 1e-11 44.5 0.1 1.2e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF1601 PF07671.6 CDJ70064.1 - 0.0064 16.0 0.4 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1601) DUF3338 PF11819.3 CDJ70064.1 - 0.11 11.9 0.5 0.18 11.2 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3338) Abhydrolase_4 PF08386.5 CDJ70064.1 - 0.18 11.7 0.6 0.32 10.9 0.2 1.6 1 1 1 2 2 2 0 TAP-like protein Draxin PF15550.1 CDJ70066.1 - 0.19 11.3 13.2 0.22 11.1 9.1 1.2 1 0 0 1 1 1 0 Draxin DUF572 PF04502.8 CDJ70066.1 - 7.9 5.6 19.3 9.9 5.2 13.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nha1_C PF08619.5 CDJ70066.1 - 9.7 5.3 19.2 11 5.1 13.3 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus CGI-121 PF08617.5 CDJ70067.1 - 5.6e-12 45.6 0.2 2.6e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 Kinase binding protein CGI-121 RAB3GAP2_N PF14655.1 CDJ70067.1 - 0.002 17.1 5.6 0.002 17.1 3.9 2.4 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF755 PF05501.6 CDJ70067.1 - 0.0044 17.0 25.8 0.0044 17.0 17.9 4.4 4 0 0 4 4 3 1 Domain of unknown function (DUF755) Plasmodium_Vir PF05795.6 CDJ70067.1 - 0.0062 15.7 3.5 0.0062 15.7 2.4 2.0 2 0 0 2 2 2 1 Plasmodium vivax Vir protein Med15 PF09606.5 CDJ70067.1 - 0.071 11.3 51.4 0.18 9.9 16.8 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDJ70067.1 - 0.1 11.6 21.4 0.1 11.6 4.8 2.3 2 0 0 2 2 2 0 Fms-interacting protein Suf PF05843.9 CDJ70067.1 - 0.22 11.1 17.6 0.6 9.7 4.0 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AAA_23 PF13476.1 CDJ70067.1 - 0.48 10.7 11.6 3.2 8.0 3.4 2.2 2 0 0 2 2 2 0 AAA domain DUF1510 PF07423.6 CDJ70067.1 - 0.74 9.1 14.7 1.2 8.4 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SRP-alpha_N PF04086.8 CDJ70067.1 - 1.1 8.6 15.3 0.88 8.8 4.5 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF3801 PF12687.2 CDJ70067.1 - 1.3 8.5 11.8 2.5 7.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Peptidase_S49_N PF08496.5 CDJ70067.1 - 1.9 8.2 7.8 5.8 6.6 0.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Band_3_cyto PF07565.8 CDJ70067.1 - 2.3 7.6 14.7 3.9 6.9 2.3 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Hid1 PF12722.2 CDJ70067.1 - 3 5.4 17.7 0.8 7.3 6.4 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.1 CDJ70067.1 - 3.3 5.2 37.0 0.22 9.1 9.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) AUX_IAA PF02309.11 CDJ70067.1 - 4 7.1 11.1 4.1 7.0 2.7 2.3 2 0 0 2 2 2 0 AUX/IAA family Nha1_C PF08619.5 CDJ70067.1 - 4.4 6.4 18.5 9.7 5.3 0.2 2.3 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus TFIIA PF03153.8 CDJ70067.1 - 5.7 6.7 36.4 1.2 9.0 7.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.1 CDJ70067.1 - 9.6 5.8 9.0 44 3.7 0.0 2.5 2 0 0 2 2 2 0 FAM176 family Activator_LAG-3 PF11498.3 CDJ70068.1 - 3.9 6.0 39.1 0.0057 15.4 10.1 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF3678 PF12435.3 CDJ70069.1 - 0.002 17.6 3.6 0.0032 16.9 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3678) SR-25 PF10500.4 CDJ70069.1 - 0.0052 16.2 8.7 0.0056 16.1 6.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 CDJ70069.1 - 0.0055 16.8 2.2 0.0057 16.8 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) AF-4 PF05110.8 CDJ70069.1 - 0.42 8.4 10.0 0.46 8.3 6.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF755 PF05501.6 CDJ70069.1 - 1.9 8.5 13.3 2.4 8.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) GEMIN8 PF15348.1 CDJ70070.1 - 0.0049 16.9 0.3 0.0049 16.9 0.2 4.9 5 0 0 5 5 5 1 Gemini of Cajal bodies-associated protein 8 DUF4483 PF14825.1 CDJ70070.1 - 0.012 15.3 1.0 0.012 15.3 0.7 5.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4483) B12D PF06522.6 CDJ70070.1 - 0.036 13.7 0.0 0.22 11.2 0.0 2.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Abhydrolase_6 PF12697.2 CDJ70071.1 - 1.1e-27 97.3 0.6 1.1e-27 97.3 0.4 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDJ70071.1 - 1.6e-12 47.4 0.0 3.5e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDJ70071.1 - 3.2e-09 36.6 0.2 2.8e-08 33.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 CDJ70071.1 - 0.00012 20.6 0.3 0.23 9.9 0.0 2.1 2 0 0 2 2 2 2 Ndr family Thioesterase PF00975.15 CDJ70071.1 - 0.00014 22.1 0.7 0.00022 21.5 0.5 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 CDJ70071.1 - 0.0032 17.0 0.1 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.20 CDJ70071.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 CDJ70071.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.7 1 1 0 1 1 1 0 Putative lysophospholipase DUF755 PF05501.6 CDJ70071.1 - 8.7 6.4 12.1 19 5.3 8.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Utp14 PF04615.8 CDJ70072.1 - 1.4 7.0 33.9 1.7 6.7 23.5 1.0 1 0 0 1 1 1 0 Utp14 protein TPK_catalytic PF04263.11 CDJ70073.1 - 2.3e-06 27.2 0.0 1e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain SR-25 PF10500.4 CDJ70073.1 - 0.016 14.7 13.4 0.15 11.5 7.0 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DivIC PF04977.10 CDJ70073.1 - 7.4 6.1 8.8 14 5.2 6.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF755 PF05501.6 CDJ70073.1 - 8.6 6.4 23.7 1.2 9.1 7.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) IPPT PF01715.12 CDJ70074.1 - 2e-20 72.8 0.0 2.8e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 IPP transferase AAA_16 PF13191.1 CDJ70074.1 - 0.00051 20.0 0.8 0.00072 19.5 0.5 1.5 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 CDJ70074.1 - 0.0013 17.9 0.1 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_17 PF13207.1 CDJ70074.1 - 0.0015 19.3 0.0 0.0032 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CDJ70074.1 - 0.0023 17.6 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 CDJ70074.1 - 0.003 16.9 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 CDJ70074.1 - 0.005 16.7 0.6 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CDJ70074.1 - 0.0058 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 CDJ70074.1 - 0.006 16.7 0.1 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDJ70074.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.15 CDJ70074.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase IPT PF01745.11 CDJ70074.1 - 0.019 14.1 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_33 PF13671.1 CDJ70074.1 - 0.02 14.7 0.0 0.062 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDJ70074.1 - 0.022 14.2 19.3 0.038 13.4 13.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Conotoxin PF02950.12 CDJ70074.1 - 0.026 15.2 1.0 0.026 15.2 0.7 2.3 2 0 0 2 2 1 0 Conotoxin ArgK PF03308.11 CDJ70074.1 - 0.031 13.0 0.0 0.06 12.1 0.0 1.4 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 CDJ70074.1 - 0.042 13.5 0.2 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 CDJ70074.1 - 0.046 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CDJ70074.1 - 0.047 13.5 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CDJ70074.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CDJ70074.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase SRP54 PF00448.17 CDJ70074.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 CDJ70074.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 CDJ70074.1 - 0.11 11.9 0.0 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 CDJ70074.1 - 0.12 12.6 0.0 0.76 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CDJ70074.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 CDJ70074.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Pex14_N PF04695.8 CDJ70074.1 - 0.32 11.0 9.1 0.68 9.9 2.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK2AP PF09806.4 CDJ70074.1 - 0.63 10.2 9.4 0.68 10.1 4.4 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Maf1 PF09174.5 CDJ70074.1 - 0.82 9.4 4.0 1.3 8.8 2.8 1.3 1 0 0 1 1 1 0 Maf1 regulator Suf PF05843.9 CDJ70074.1 - 6.1 6.4 6.7 2.7 7.6 0.9 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Lycopene_cycl PF05834.7 CDJ70076.1 - 0.0087 15.0 4.0 0.014 14.3 2.8 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Lipoprotein_2 PF00921.12 CDJ70076.1 - 0.15 12.0 8.5 0.27 11.2 5.9 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein DUF3499 PF12005.3 CDJ70076.1 - 0.65 10.1 7.5 0.16 12.1 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) DUF912 PF06024.7 CDJ70076.1 - 0.72 9.9 7.1 0.47 10.5 1.2 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FLO_LFY PF01698.11 CDJ70076.1 - 0.77 8.5 7.7 0.039 12.8 1.2 1.8 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF1840 PF08895.6 CDJ70076.1 - 1.1 9.2 12.1 0.52 10.3 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) SOBP PF15279.1 CDJ70076.1 - 1.4 9.2 12.1 0.42 10.9 3.8 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein Ctr PF04145.10 CDJ70076.1 - 7.7 6.5 11.0 7.1 6.6 4.7 2.1 2 0 0 2 2 2 0 Ctr copper transporter family zf-C3HC4_3 PF13920.1 CDJ70077.1 - 2e-08 33.7 8.9 2e-08 33.7 6.2 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ70077.1 - 1.1e-05 25.3 11.3 1.1e-05 25.3 7.8 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDJ70077.1 - 3.2e-05 23.6 11.5 3.2e-05 23.6 8.0 2.9 3 0 0 3 3 3 1 Ring finger domain DUF572 PF04502.8 CDJ70077.1 - 7.4e-05 22.1 9.8 7.4e-05 22.1 6.8 2.5 2 1 0 2 2 2 1 Family of unknown function (DUF572) zf-RING_5 PF14634.1 CDJ70077.1 - 0.0021 17.7 9.4 0.0021 17.7 6.5 3.5 3 1 1 4 4 4 1 zinc-RING finger domain SASRP1 PF15160.1 CDJ70077.1 - 0.39 9.9 2.8 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 FimP PF09766.4 CDJ70078.1 - 0.00089 18.4 18.5 0.004 16.2 1.0 2.1 2 0 0 2 2 2 2 Fms-interacting protein Med15 PF09606.5 CDJ70078.1 - 0.0013 17.0 50.4 0.0021 16.3 34.9 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ70078.1 - 0.0016 18.3 20.5 0.0025 17.8 14.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2309 PF10070.4 CDJ70078.1 - 0.002 16.3 3.1 0.0026 15.9 2.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) NAD_binding_9 PF13454.1 CDJ70078.1 - 0.007 16.1 0.3 0.007 16.1 0.2 2.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding DUF605 PF04652.11 CDJ70078.1 - 0.0084 15.5 14.0 0.011 15.1 9.7 1.2 1 0 0 1 1 1 1 Vta1 like FAD_binding_3 PF01494.14 CDJ70078.1 - 0.042 12.8 0.1 0.042 12.8 0.1 1.7 2 0 0 2 2 1 0 FAD binding domain NAD_binding_8 PF13450.1 CDJ70078.1 - 0.043 13.8 0.0 0.043 13.8 0.0 2.7 3 0 0 3 3 1 0 NAD(P)-binding Rossmann-like domain DUF3115 PF11312.3 CDJ70078.1 - 0.056 12.2 0.8 0.084 11.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) DUF4647 PF15504.1 CDJ70078.1 - 0.09 11.6 12.2 0.13 11.1 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DDHD PF02862.12 CDJ70078.1 - 0.13 12.0 7.2 0.21 11.3 5.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF2722 PF10846.3 CDJ70078.1 - 0.17 10.9 17.3 0.038 13.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Thi4 PF01946.12 CDJ70078.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DHHW PF14286.1 CDJ70078.1 - 0.32 10.2 3.4 0.43 9.8 2.4 1.1 1 0 0 1 1 1 0 DHHW protein Topoisom_I_N PF02919.10 CDJ70078.1 - 0.36 10.1 4.4 1.2 8.3 0.6 2.0 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF912 PF06024.7 CDJ70078.1 - 0.38 10.8 9.5 0.84 9.7 0.9 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S46 PF10459.4 CDJ70078.1 - 0.45 8.8 8.2 0.6 8.4 5.7 1.1 1 0 0 1 1 1 0 Peptidase S46 HemX PF04375.9 CDJ70078.1 - 0.5 8.9 22.5 0.88 8.0 15.6 1.3 1 1 0 1 1 1 0 HemX Rxt3 PF08642.5 CDJ70078.1 - 0.52 10.5 5.8 2.2 8.5 0.2 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Peptidase_S49_N PF08496.5 CDJ70078.1 - 0.58 9.9 9.1 4.2 7.1 0.2 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RIC3 PF15361.1 CDJ70078.1 - 0.59 10.3 12.1 2.8 8.1 1.7 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 PAT1 PF09770.4 CDJ70078.1 - 0.65 8.1 42.3 0.81 7.8 29.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_DNAp_acc PF04929.7 CDJ70078.1 - 0.77 8.6 11.5 1.1 8.1 8.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNA_pol_Rbc25 PF08292.7 CDJ70078.1 - 1.5 9.0 7.9 6.4 6.9 0.8 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Pex14_N PF04695.8 CDJ70078.1 - 3 7.8 27.5 0.18 11.8 3.9 2.4 3 0 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.14 CDJ70078.1 - 3.4 8.1 16.5 2.1 8.8 8.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein eIF_4EBP PF05456.6 CDJ70078.1 - 3.6 7.3 11.0 4.9 6.8 1.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) eIF-3_zeta PF05091.7 CDJ70078.1 - 7.3 5.0 14.9 12 4.3 10.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AIF_C PF14721.1 CDJ70078.1 - 7.5 6.8 9.4 6.3 7.0 0.8 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1266 PF06889.6 CDJ70078.1 - 8.1 6.2 8.0 15 5.3 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DUF3371 PF11851.3 CDJ70078.1 - 9.1 6.9 26.9 0.8 10.4 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) TMEM51 PF15345.1 CDJ70079.1 - 0.72 9.5 4.2 0.19 11.3 0.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 TORC_M PF12885.2 CDJ70080.1 - 0.3 10.8 9.3 1 9.0 6.5 1.9 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Neur_chan_memb PF02932.11 CDJ70080.1 - 0.42 10.4 2.4 0.49 10.2 1.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.7 CDJ70080.1 - 0.8 8.2 13.3 1.1 7.8 9.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2072 PF09845.4 CDJ70080.1 - 5.8 6.8 8.4 10 6.0 5.8 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Hid1 PF12722.2 CDJ70080.1 - 6.6 4.2 8.6 8.3 3.9 6.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Baculo_PP31 PF05311.6 CDJ70080.1 - 7.1 5.8 12.4 11 5.1 8.6 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CDK5_activator PF03261.10 CDJ70080.1 - 9.3 5.4 11.2 19 4.4 7.8 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Suf PF05843.9 CDJ70080.1 - 9.3 5.8 15.8 18 4.9 11.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-CDGSH PF09360.5 CDJ70081.1 - 2e-12 46.7 0.2 3.6e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type DUF1183 PF06682.7 CDJ70081.1 - 0.00084 19.0 0.1 0.00094 18.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Trep_Strep PF09605.5 CDJ70081.1 - 0.0049 16.5 0.0 0.0059 16.2 0.0 1.1 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2076 PF09849.4 CDJ70081.1 - 0.0067 16.5 2.5 0.0086 16.1 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2309 PF10070.4 CDJ70081.1 - 0.011 13.9 0.2 0.012 13.7 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Phage_H_T_join PF05521.6 CDJ70081.1 - 0.041 14.1 0.4 0.076 13.3 0.3 1.4 1 0 0 1 1 1 0 Phage head-tail joining protein DUF1049 PF06305.6 CDJ70081.1 - 3 7.4 7.5 7.4 6.1 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) EF-hand_4 PF12763.2 CDJ70082.1 - 8.8e-14 51.1 0.0 1.5e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CDJ70082.1 - 0.0025 17.0 0.0 0.0071 15.5 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CDJ70082.1 - 0.01 15.9 0.0 0.5 10.5 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.1 CDJ70082.1 - 0.07 13.0 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 CDJ70082.1 - 0.076 12.6 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair CAP PF00188.21 CDJ70083.1 - 0.055 13.9 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Surface_antigen PF11054.3 CDJ70084.1 - 0.059 12.7 0.5 1.2 8.4 0.0 2.5 2 1 1 3 3 3 0 Sporozoite TA4 surface antigen CAP PF00188.21 CDJ70085.1 - 0.046 14.2 1.0 0.089 13.2 0.7 1.6 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Tom37 PF10568.4 CDJ70085.1 - 0.13 12.5 0.1 0.47 10.7 0.0 1.9 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein CAP PF00188.21 CDJ70086.1 - 0.024 15.1 0.5 0.049 14.1 0.3 1.6 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Tom37 PF10568.4 CDJ70086.1 - 0.13 12.5 0.1 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF3819 PF12842.2 CDJ70086.1 - 0.22 11.2 2.1 0.52 9.9 1.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3819) CAP PF00188.21 CDJ70087.1 - 0.011 16.2 0.9 0.74 10.3 0.0 2.5 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Lustrin_cystein PF14625.1 CDJ70087.1 - 0.016 15.2 0.4 8.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain CAP PF00188.21 CDJ70089.1 - 0.00097 19.6 0.7 0.0017 18.8 0.5 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 CDJ70090.1 - 0.098 13.1 1.6 0.15 12.5 1.1 1.5 1 1 0 1 1 1 0 Cysteine-rich secretory protein family Clathrin PF00637.15 CDJ70093.1 - 3e-08 33.3 2.3 2.7e-06 27.0 0.2 3.0 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.4 CDJ70093.1 - 1.6e-05 24.9 0.0 1.6e-05 24.9 0.0 4.8 6 0 0 6 6 6 1 Vacuolar sorting protein 39 domain 2 DUF912 PF06024.7 CDJ70093.1 - 0.24 11.4 20.1 0.81 9.7 1.0 4.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spt20 PF12090.3 CDJ70093.1 - 0.63 9.3 42.1 0.17 11.2 1.5 4.4 3 1 1 4 4 4 0 Spt20 family PilX PF13681.1 CDJ70094.1 - 0.094 13.2 8.9 4.6 7.7 3.6 3.0 1 1 1 2 2 2 0 Type IV pilus assembly protein PilX C-term CytochromB561_N PF09786.4 CDJ70094.1 - 0.15 10.5 5.9 0.18 10.1 4.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal TFIIA PF03153.8 CDJ70094.1 - 6.5 6.5 12.7 10 5.8 8.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF-hand_1 PF00036.27 CDJ70095.1 - 1.7e-16 58.2 0.1 2.5e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CDJ70095.1 - 1.4e-12 46.3 0.1 1.1e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CDJ70095.1 - 3.9e-12 46.1 0.0 5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CDJ70095.1 - 4.6e-12 45.3 0.2 1.9e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CDJ70095.1 - 8.2e-10 37.5 0.2 1.1e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 CDJ70095.1 - 0.0019 18.0 0.0 0.0025 17.6 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain Caleosin PF05042.8 CDJ70095.1 - 0.038 13.5 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Caleosin related protein DUF3335 PF11814.3 CDJ70095.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase_C39 like family Cript PF10235.4 CDJ70096.1 - 3.1e-15 56.2 5.9 3.1e-15 56.2 4.1 1.7 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT C6_DPF PF10170.4 CDJ70096.1 - 0.11 12.5 4.4 0.18 11.9 3.1 1.6 1 1 0 1 1 1 0 Cysteine-rich domain DZR PF12773.2 CDJ70096.1 - 0.36 10.6 9.5 0.61 9.9 3.3 2.5 1 1 1 2 2 2 0 Double zinc ribbon DiS_P_DiS PF06750.8 CDJ70096.1 - 1 9.1 6.9 0.81 9.5 2.3 2.4 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Sar8_2 PF03058.9 CDJ70096.1 - 2 8.7 11.1 1.1 9.6 5.0 2.1 1 1 1 2 2 2 0 Sar8.2 family C1_1 PF00130.17 CDJ70096.1 - 3.1 7.6 11.6 19 5.0 6.5 2.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 CDJ70096.1 - 5.7 6.7 11.3 25 4.6 5.5 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Kelch_1 PF01344.20 CDJ70097.1 - 9.8e-44 146.6 0.7 1.2e-08 34.3 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 CDJ70097.1 - 6.5e-40 134.4 22.9 7.8e-07 29.0 0.0 9.0 9 0 0 9 9 9 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CDJ70097.1 - 7.9e-39 131.1 23.0 5.1e-08 32.5 0.0 6.8 5 1 2 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.10 CDJ70097.1 - 1.4e-36 122.9 18.9 1.4e-07 30.9 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 CDJ70097.1 - 3.1e-35 118.9 10.4 2.6e-06 27.3 0.0 6.5 2 2 4 6 6 6 6 Kelch motif Kelch_5 PF13854.1 CDJ70097.1 - 4.5e-31 106.2 5.5 3.4e-06 26.8 0.0 6.7 6 0 0 6 6 6 6 Kelch motif BTB PF00651.26 CDJ70097.1 - 2.9e-15 56.2 0.0 2.7e-14 53.1 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain Hom_end_hint PF05203.11 CDJ70097.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 Hom_end-associated Hint V_ATPase_I PF01496.14 CDJ70099.1 - 1.8e-36 125.3 1.5 6.8e-19 67.2 0.1 4.7 3 1 1 4 4 4 4 V-type ATPase 116kDa subunit family SR-25 PF10500.4 CDJ70099.1 - 4.4 6.7 14.2 9.7 5.5 9.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Proteasome PF00227.21 CDJ70100.1 - 3e-45 153.8 0.0 4e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDJ70100.1 - 7e-11 41.2 0.0 7e-11 41.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ATG16 PF08614.6 CDJ70101.1 - 0.0049 16.7 11.0 0.0063 16.3 7.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4391 PF14335.1 CDJ70101.1 - 0.01 15.2 5.9 0.012 14.9 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) UBA_e1_C PF09358.5 CDJ70101.1 - 0.013 15.7 1.2 0.017 15.3 0.8 1.2 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain ORF6C PF10552.4 CDJ70101.1 - 0.033 13.9 4.5 0.057 13.1 3.1 1.4 1 0 0 1 1 1 0 ORF6C domain Cluap1 PF10234.4 CDJ70101.1 - 0.082 12.0 7.2 0.079 12.1 5.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF2265 PF10023.4 CDJ70101.1 - 0.27 10.3 1.7 0.36 9.9 1.2 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) TMF_TATA_bd PF12325.3 CDJ70101.1 - 0.6 9.8 8.1 0.69 9.6 5.3 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 CDJ70101.1 - 0.73 9.7 9.3 0.35 10.7 5.3 1.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4558 PF15104.1 CDJ70101.1 - 1.1 9.2 7.9 5.5 6.9 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) APG6 PF04111.7 CDJ70101.1 - 1.5 7.7 8.7 1.7 7.6 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 CDJ70101.1 - 2.1 7.8 9.2 5.8 6.4 4.1 2.4 1 1 1 2 2 2 0 Septum formation initiator IMD PF08397.6 CDJ70101.1 - 5.2 6.3 11.6 2.2 7.5 6.7 1.3 1 1 0 1 1 1 0 IRSp53/MIM homology domain DHC_N1 PF08385.7 CDJ70102.1 - 2.2e-18 66.0 0.1 6.3e-17 61.1 0.2 2.0 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 DHC_N1 PF08385.7 CDJ70103.1 - 3.3e-45 154.5 6.1 2.7e-27 95.4 4.0 2.9 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CDJ70104.1 - 3.7e-112 374.8 6.6 3.7e-112 374.8 4.6 2.9 2 2 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDJ70104.1 - 7.7e-54 182.6 0.1 4.6e-50 170.3 0.0 2.5 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CDJ70104.1 - 2.6e-10 40.1 0.0 1.2e-06 28.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CDJ70104.1 - 0.015 14.7 0.1 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nab2 PF11517.3 CDJ70104.1 - 0.027 14.5 0.0 0.22 11.6 0.0 2.5 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) T2SE PF00437.15 CDJ70104.1 - 0.03 13.2 0.3 0.076 11.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein APS_kinase PF01583.15 CDJ70104.1 - 0.047 13.3 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 CDJ70104.1 - 0.065 13.2 0.2 0.76 9.7 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_30 PF13604.1 CDJ70104.1 - 0.11 11.9 0.4 0.28 10.7 0.3 1.6 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.2 CDJ70105.1 - 2.6e-73 246.2 2.3 2.9e-73 246.1 0.1 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CDJ70105.1 - 1.5e-40 138.9 0.0 4.6e-40 137.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 CDJ70105.1 - 5.4e-34 117.4 20.9 7.9e-33 113.6 14.5 2.3 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CDJ70105.1 - 3.3e-08 33.3 0.0 0.00026 20.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDJ70105.1 - 0.0011 18.9 10.6 3.2 7.6 0.0 4.8 4 1 1 5 5 5 2 AAA ATPase domain AAA PF00004.24 CDJ70105.1 - 0.002 18.3 2.1 0.3 11.2 0.0 4.0 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) TetR_C_8 PF14278.1 CDJ70105.1 - 0.066 13.6 4.2 2 8.8 0.9 3.1 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Laminin_I PF06008.9 CDJ70105.1 - 0.19 11.0 26.9 0.3 10.3 3.1 3.1 2 1 1 3 3 3 0 Laminin Domain I Mac PF12464.3 CDJ70105.1 - 0.19 11.7 2.2 0.69 9.9 0.1 2.7 2 0 0 2 2 2 0 Maltose acetyltransferase Reo_sigmaC PF04582.7 CDJ70105.1 - 0.46 9.6 2.0 0.83 8.7 0.2 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ATP-synt_B PF00430.13 CDJ70105.1 - 2.3 8.0 33.6 2.8 7.7 10.2 2.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) SH3BP5 PF05276.9 CDJ70105.1 - 3.2 6.9 23.8 1.5 8.0 8.3 2.4 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) IncA PF04156.9 CDJ70105.1 - 5 6.6 23.9 4.8 6.7 4.5 2.3 2 0 0 2 2 2 0 IncA protein AAA_9 PF12781.2 CDJ70106.1 - 1.9e-41 141.3 0.0 2.4e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 Dynein_heavy PF03028.10 CDJ70107.1 - 2e-182 607.9 0.0 1.3e-136 456.5 0.0 2.1 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 CDJ70107.1 - 0.0001 21.2 1.9 0.00019 20.4 1.3 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 Motilin_ghrelin PF04644.7 CDJ70107.1 - 0.037 13.8 0.2 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 Motilin/ghrelin Surface_antigen PF11054.3 CDJ70108.1 - 1.5e-76 257.1 0.4 1.7e-76 257.0 0.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ70109.1 - 9.5e-95 316.7 7.6 2.6e-72 243.2 3.4 2.0 2 0 0 2 2 2 2 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ70110.1 - 2.9e-70 236.5 0.0 3.2e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ70111.1 - 5.3e-64 216.0 0.1 6.4e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Tom7 PF08038.7 CDJ70111.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 TOM7 family Surface_antigen PF11054.3 CDJ70112.1 - 1.4e-59 201.5 1.8 6.9e-58 196.0 1.2 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen AlaDh_PNT_N PF05222.10 CDJ70113.1 - 1.2e-37 128.9 0.1 1.6e-37 128.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain WBP-1 PF11669.3 CDJ70113.1 - 0.013 15.6 2.5 0.057 13.4 0.4 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 IncA PF04156.9 CDJ70113.1 - 0.024 14.2 4.4 0.058 12.9 3.1 1.6 1 1 0 1 1 1 0 IncA protein LST1 PF05083.8 CDJ70113.1 - 0.043 13.8 1.2 0.043 13.8 0.9 1.9 2 0 0 2 2 2 0 LST-1 protein TSA PF03249.8 CDJ70113.1 - 0.88 8.0 5.6 1.2 7.5 3.9 1.1 1 0 0 1 1 1 0 Type specific antigen RRM_6 PF14259.1 CDJ70116.1 - 1.1e-22 79.7 0.0 4.3e-10 39.4 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ70116.1 - 1.7e-21 75.6 0.1 1.9e-08 33.8 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ70116.1 - 9.3e-12 44.6 2.4 0.0018 18.1 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 CDJ70116.1 - 1.4e-06 27.0 28.5 1.4e-06 27.0 19.7 2.5 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CDJ70116.1 - 0.42 10.3 106.9 0.054 13.2 27.6 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1777) Aa_trans PF01490.13 CDJ70117.1 - 1.5e-06 26.9 5.4 1.5e-06 26.9 3.7 2.1 3 0 0 3 3 3 1 Transmembrane amino acid transporter protein Peptidase_M24 PF00557.19 CDJ70118.1 - 1.4e-33 116.1 0.6 2e-33 115.7 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Med3 PF11593.3 CDJ70118.1 - 0.04 13.1 6.1 0.058 12.6 4.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDK2AP PF09806.4 CDJ70118.1 - 0.16 12.1 2.7 0.24 11.5 1.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2324 PF10086.4 CDJ70120.1 - 0.013 14.7 2.2 0.035 13.3 1.5 1.7 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) FimP PF09766.4 CDJ70120.1 - 0.15 11.1 9.6 0.21 10.5 6.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein Ashwin PF15323.1 CDJ70120.1 - 1.1 9.1 11.6 2.3 8.1 5.3 2.1 2 0 0 2 2 2 0 Developmental protein Lin-8 PF03353.10 CDJ70120.1 - 4.3 6.5 9.9 7.2 5.7 6.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.4 CDJ70121.1 - 0.058 12.8 3.7 0.084 12.3 2.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chromate_transp PF02417.10 CDJ70121.1 - 0.34 10.5 5.6 0.49 9.9 3.9 1.2 1 0 0 1 1 1 0 Chromate transporter Draxin PF15550.1 CDJ70121.1 - 3.1 7.3 5.1 3.8 7.0 3.5 1.2 1 0 0 1 1 1 0 Draxin DSBA PF01323.15 CDJ70121.1 - 5.1 6.5 12.9 7.4 6.0 8.9 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Vps52 PF04129.7 CDJ70122.1 - 8e-14 51.0 1.1 1.1e-13 50.5 0.8 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Macoilin PF09726.4 CDJ70122.1 - 0.064 11.5 10.9 0.096 10.9 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 CDJ70122.1 - 0.94 8.0 5.3 1.3 7.6 3.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SRP-alpha_N PF04086.8 CDJ70122.1 - 0.97 8.7 10.7 1.3 8.2 7.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF572 PF04502.8 CDJ70122.1 - 5.5 6.1 8.8 8.2 5.5 6.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SR-25 PF10500.4 CDJ70123.1 - 0.0035 16.8 13.2 0.0035 16.8 9.1 1.5 1 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 CDJ70123.1 - 1.1 9.5 5.7 5.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Dehydrin DUF1645 PF07816.6 CDJ70123.1 - 3.6 8.0 12.1 4.3 7.7 8.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) DUF755 PF05501.6 CDJ70123.1 - 7.2 6.7 10.4 0.58 10.2 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) ASXH PF13919.1 CDJ70124.1 - 0.073 12.8 0.2 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Asx homology domain PP2C PF00481.16 CDJ70125.1 - 5.9e-30 104.4 0.2 1.2e-18 67.4 0.1 4.1 4 0 0 4 4 4 3 Protein phosphatase 2C zf-C2H2_4 PF13894.1 CDJ70127.1 - 6.3 7.3 8.2 6.6 7.3 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger LsmAD PF06741.8 CDJ70128.1 - 2.3e-12 46.8 0.7 2.3e-12 46.8 0.5 3.2 2 1 0 2 2 2 1 LsmAD domain CcmD PF04995.9 CDJ70129.1 - 0.27 11.0 0.0 0.27 11.0 0.0 4.7 5 0 0 5 5 5 0 Heme exporter protein D (CcmD) SPX PF03105.14 CDJ70130.1 - 0.034 13.9 2.6 0.061 13.0 1.8 1.4 1 0 0 1 1 1 0 SPX domain CAF1A PF12253.3 CDJ70130.1 - 0.86 9.7 19.4 2.4 8.3 13.4 1.8 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Pex14_N PF04695.8 CDJ70132.1 - 0.00022 21.2 7.5 0.00022 21.2 5.2 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDJ70132.1 - 0.0035 16.4 9.1 0.0035 16.4 6.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein CDC45 PF02724.9 CDJ70132.1 - 0.046 11.7 3.1 0.044 11.8 2.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.8 CDJ70132.1 - 0.051 13.0 4.8 0.051 13.0 3.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAS PF00989.19 CDJ70132.1 - 0.055 13.2 3.4 0.066 12.9 2.4 1.1 1 0 0 1 1 1 0 PAS fold RR_TM4-6 PF06459.7 CDJ70132.1 - 0.057 13.3 5.3 0.064 13.1 3.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF912 PF06024.7 CDJ70132.1 - 0.06 13.3 0.5 0.072 13.1 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Suf PF05843.9 CDJ70132.1 - 0.068 12.8 11.9 0.066 12.9 8.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF913 PF06025.7 CDJ70132.1 - 0.082 11.6 2.2 0.079 11.7 1.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MscS_TM PF12794.2 CDJ70132.1 - 0.095 11.2 4.3 0.1 11.1 3.0 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Gemini_mov PF01708.11 CDJ70132.1 - 0.11 12.0 0.9 0.17 11.4 0.6 1.5 1 1 0 1 1 1 0 Geminivirus putative movement protein Kei1 PF08552.6 CDJ70132.1 - 0.14 11.8 0.7 0.14 11.7 0.5 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FAD-SLDH PF12318.3 CDJ70132.1 - 0.15 11.7 3.0 0.18 11.4 2.1 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Ctr PF04145.10 CDJ70132.1 - 0.22 11.5 2.9 0.26 11.3 2.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Folate_carrier PF01770.13 CDJ70132.1 - 0.26 9.7 1.6 0.29 9.5 1.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier Serinc PF03348.10 CDJ70132.1 - 0.27 9.9 3.9 0.27 9.9 2.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NARP1 PF12569.3 CDJ70132.1 - 0.27 9.9 6.6 0.28 9.8 4.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RED_N PF07808.8 CDJ70132.1 - 0.27 10.3 9.3 0.28 10.3 6.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2547 PF10818.3 CDJ70132.1 - 0.29 11.7 16.1 0.34 11.5 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Gti1_Pac2 PF09729.4 CDJ70132.1 - 0.29 10.9 2.8 0.3 10.9 2.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family AIF_C PF14721.1 CDJ70132.1 - 0.31 11.2 4.0 0.33 11.2 2.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DHHW PF14286.1 CDJ70132.1 - 0.36 10.0 2.9 0.37 10.0 2.0 1.0 1 0 0 1 1 1 0 DHHW protein Peptidase_U57 PF05582.7 CDJ70132.1 - 0.37 9.7 3.1 0.35 9.7 2.2 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Glyco_transf_15 PF01793.11 CDJ70132.1 - 0.43 9.4 4.2 0.45 9.3 2.9 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Spt20 PF12090.3 CDJ70132.1 - 0.44 9.8 10.9 0.48 9.7 7.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF4557 PF15101.1 CDJ70132.1 - 0.46 10.2 12.1 0.47 10.2 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Peptidase_S49_N PF08496.5 CDJ70132.1 - 0.61 9.8 4.4 0.64 9.8 3.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3371 PF11851.3 CDJ70132.1 - 0.67 10.6 13.4 0.75 10.4 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF1631 PF07793.6 CDJ70132.1 - 0.73 7.8 11.8 0.83 7.7 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) OATP PF03137.15 CDJ70132.1 - 0.75 7.7 3.3 0.76 7.7 2.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Het-C PF07217.6 CDJ70132.1 - 1 7.4 4.5 1.1 7.4 3.1 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3357 PF11837.3 CDJ70132.1 - 1 9.2 4.1 1.2 9.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) CPSF100_C PF13299.1 CDJ70132.1 - 1.5 9.0 7.1 1.4 9.0 4.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FCP1_C PF09309.5 CDJ70132.1 - 1.6 7.9 12.7 1.9 7.7 8.8 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF3408 PF11888.3 CDJ70132.1 - 2.8 7.8 9.5 3.3 7.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Med15 PF09606.5 CDJ70132.1 - 3.3 5.7 30.6 3.2 5.8 21.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc1_Nup PF09531.5 CDJ70132.1 - 3.4 5.9 6.5 3.4 5.9 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATAD4 PF15321.1 CDJ70132.1 - 3.9 8.5 9.0 4.9 8.2 6.2 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Lin-8 PF03353.10 CDJ70132.1 - 3.9 6.6 11.4 4.1 6.5 7.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.4 CDJ70132.1 - 4.1 5.5 25.5 4.2 5.4 17.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 CDJ70132.1 - 5.2 6.7 8.3 5.6 6.6 5.7 1.1 1 0 0 1 1 1 0 AUX/IAA family DDHD PF02862.12 CDJ70132.1 - 6.4 6.4 9.2 7.2 6.3 6.4 1.1 1 0 0 1 1 1 0 DDHD domain LIM_bind PF01803.11 CDJ70132.1 - 6.5 5.7 11.5 7.2 5.6 8.0 1.1 1 0 0 1 1 1 0 LIM-domain binding protein BORG_CEP PF14957.1 CDJ70132.1 - 7.4 7.5 8.1 8.3 7.3 5.6 1.1 1 0 0 1 1 1 0 Cdc42 effector SprA-related PF12118.3 CDJ70132.1 - 7.8 5.7 23.9 8.5 5.6 16.5 1.0 1 0 0 1 1 1 0 SprA-related family DUF4175 PF13779.1 CDJ70132.1 - 8.1 4.0 29.3 8.5 3.9 20.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gag_spuma PF03276.9 CDJ70132.1 - 8.3 4.6 24.0 9 4.4 16.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF2201_N PF13203.1 CDJ70132.1 - 8.5 5.4 11.6 9.2 5.3 8.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Shisa PF13908.1 CDJ70132.1 - 9.4 6.3 11.9 10 6.2 8.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Hid1 PF12722.2 CDJ70132.1 - 9.5 3.7 9.9 9.5 3.7 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex16 PF08610.5 CDJ70133.1 - 0.42 9.5 2.7 0.6 9.0 1.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Suf PF05843.9 CDJ70133.1 - 0.63 9.7 4.1 0.85 9.2 2.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 CDJ70133.1 - 1.1 9.0 7.4 1.9 8.2 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDJ70133.1 - 3.4 5.8 18.1 4.3 5.4 12.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDJ70133.1 - 7.1 4.6 34.4 0.0028 15.9 12.8 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal tRNA-synt_His PF13393.1 CDJ70134.1 - 3.3e-43 147.9 1.6 3.3e-43 147.9 1.1 4.0 2 1 2 4 4 4 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CDJ70134.1 - 2.7e-16 59.6 0.0 4.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CDJ70134.1 - 4.4e-08 32.9 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 CDJ70134.1 - 0.24 10.5 0.0 0.64 9.1 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) TFIIA PF03153.8 CDJ70134.1 - 3.8 7.3 31.4 0.61 9.9 5.0 3.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RIC3 PF15361.1 CDJ70134.1 - 3.8 7.7 10.0 0.23 11.6 0.5 3.3 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 Suf PF05843.9 CDJ70134.1 - 5 6.7 18.9 9.7 5.8 4.8 3.3 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) SMK-1 PF04802.10 CDJ70135.1 - 4.1e-11 42.7 0.7 4.7e-07 29.5 0.4 2.4 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 Peptidase_S64 PF08192.6 CDJ70137.1 - 8.6 4.5 11.1 12 4.0 7.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Methyltransf_9 PF08003.6 CDJ70139.1 - 9.9 4.7 9.7 17 3.9 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Surface_antigen PF11054.3 CDJ70141.1 - 1.7e-59 201.2 0.1 2.1e-59 201.0 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ70142.1 - 5.4e-60 202.9 0.0 6.6e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen SIR2 PF02146.12 CDJ70145.1 - 8.7e-08 32.0 0.0 0.00063 19.5 0.0 3.7 3 0 0 3 3 3 3 Sir2 family LAG1-DNAbind PF09271.6 CDJ70145.1 - 0.083 13.3 0.1 0.083 13.3 0.1 2.8 4 0 0 4 4 4 0 LAG1, DNA binding WD40 PF00400.27 CDJ70146.1 - 1.9e-12 46.5 10.9 5.3e-07 29.2 0.0 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 CDJ70146.1 - 0.0085 14.2 0.0 0.012 13.7 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ACC_epsilon PF13822.1 CDJ70150.1 - 2.5 8.5 6.5 22 5.5 4.5 2.1 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Glyco_hydro_31 PF01055.21 CDJ70153.1 - 2.2e-86 290.4 0.0 3.1e-85 286.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CDJ70153.1 - 0.00087 19.0 0.1 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like OATP PF03137.15 CDJ70153.1 - 0.19 9.7 2.6 6.1 4.7 0.1 2.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family COX6A PF02046.10 CDJ70154.1 - 1.4 8.8 10.2 0.03 14.2 0.6 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa Ras PF00071.17 CDJ70157.1 - 3.7e-40 136.9 0.0 4.4e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ70157.1 - 1.9e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDJ70157.1 - 5.3e-12 45.3 0.0 6.1e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CDJ70157.1 - 1.8e-05 24.6 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CDJ70157.1 - 1.8e-05 23.9 0.0 2.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDJ70157.1 - 0.00033 20.1 0.0 0.0017 17.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CDJ70157.1 - 0.079 12.1 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 CDJ70158.1 - 3.7e-57 192.2 0.0 4.3e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDJ70158.1 - 6.8e-21 74.9 0.0 9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDJ70158.1 - 1e-14 54.1 0.0 1.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CDJ70158.1 - 1.2e-06 28.1 0.0 3.2e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDJ70158.1 - 7.4e-06 25.9 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CDJ70158.1 - 9.1e-05 21.7 0.0 0.00011 21.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 CDJ70158.1 - 0.0014 18.2 0.0 0.29 10.6 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 CDJ70158.1 - 0.0051 16.0 0.0 0.06 12.6 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CDJ70158.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CDJ70158.1 - 0.016 15.2 0.3 0.032 14.2 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CDJ70158.1 - 0.02 15.0 0.0 0.06 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CDJ70158.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 CDJ70158.1 - 0.068 13.0 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CDJ70158.1 - 0.07 12.5 0.1 0.87 9.0 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CDJ70158.1 - 0.078 11.7 0.0 2 7.1 0.0 2.1 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 CDJ70158.1 - 0.15 12.3 0.1 0.38 11.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AP2 PF00847.15 CDJ70162.1 - 0.002 18.2 1.6 0.002 18.2 1.1 2.8 3 0 0 3 3 3 1 AP2 domain Med15 PF09606.5 CDJ70163.1 - 0.16 10.1 17.5 0.22 9.7 12.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDJ70166.1 - 0.0095 13.7 2.9 0.0094 13.7 2.0 1.0 1 0 0 1 1 1 1 Ycf1 Activator_LAG-3 PF11498.3 CDJ70166.1 - 0.046 12.4 28.7 0.08 11.6 19.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RNase_PH_C PF03725.10 CDJ70167.1 - 0.013 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 OmpH PF03938.9 CDJ70167.1 - 0.034 14.0 0.1 0.034 14.0 0.0 3.5 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 CDJ70167.1 - 0.79 10.0 10.3 1.3 9.3 2.6 2.3 2 0 0 2 2 2 0 AAA domain TraT PF05818.7 CDJ70167.1 - 3.1 7.1 15.5 0.86 8.9 7.5 2.2 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Peptidase_S64 PF08192.6 CDJ70167.1 - 6.2 5.0 9.1 11 4.2 6.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF4064 PF13273.1 CDJ70168.1 - 0.14 12.3 2.1 0.11 12.6 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) CD20 PF04103.10 CDJ70168.1 - 3.8 7.4 7.4 0.68 9.8 0.2 2.5 1 1 1 2 2 2 0 CD20-like family Hid1 PF12722.2 CDJ70168.1 - 4.1 4.9 14.1 5.3 4.5 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2486 PF10667.4 CDJ70169.1 - 0.25 11.8 6.8 0.24 11.8 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF3235 PF11574.3 CDJ70169.1 - 0.64 10.2 6.1 0.75 10.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) MSP1_C PF07462.6 CDJ70169.1 - 2.3 6.4 4.4 2.3 6.5 3.1 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF106 PF01956.11 CDJ70170.1 - 3.1e-17 62.6 2.8 1.6e-12 47.2 0.4 2.2 2 0 0 2 2 2 2 Integral membrane protein DUF106 IncA PF04156.9 CDJ70171.1 - 0.0038 16.8 16.3 0.0048 16.5 11.3 1.1 1 0 0 1 1 1 1 IncA protein Paramyxo_ncap PF00973.14 CDJ70171.1 - 0.046 12.4 2.4 0.051 12.2 1.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein AAA_23 PF13476.1 CDJ70171.1 - 0.27 11.5 13.3 0.27 11.5 9.2 1.1 1 0 0 1 1 1 0 AAA domain DDHD PF02862.12 CDJ70171.1 - 1 9.0 8.2 1.1 9.0 5.7 1.1 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.6 CDJ70171.1 - 9.2 4.4 14.8 8.7 4.4 10.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.20 CDJ70172.1 - 4.6e-55 186.5 0.0 4.6e-55 186.5 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ70172.1 - 5.1e-26 91.2 0.0 5.1e-26 91.2 0.0 2.6 2 2 0 2 2 2 1 Protein tyrosine kinase Ycf1 PF05758.7 CDJ70172.1 - 0.73 7.4 18.7 1 6.9 13.0 1.1 1 0 0 1 1 1 0 Ycf1 Dicty_REP PF05086.7 CDJ70172.1 - 2.5 5.7 15.9 3.6 5.2 11.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GAGA_bind PF06217.7 CDJ70172.1 - 5.4 6.8 23.4 1.7 8.5 13.8 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family LMBR1 PF04791.11 CDJ70172.1 - 7.8 4.9 10.7 13 4.2 7.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GPCR_chapero_1 PF11904.3 CDJ70173.1 - 0.052 12.6 4.2 0.059 12.5 2.9 1.0 1 0 0 1 1 1 0 GPCR-chaperone DNA_pol3_a_NII PF11490.3 CDJ70173.1 - 0.12 12.0 13.4 0.12 11.9 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Peptidase_M56 PF05569.6 CDJ70173.1 - 0.17 10.8 0.9 0.18 10.7 0.6 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF4557 PF15101.1 CDJ70173.1 - 0.28 10.9 17.3 0.3 10.9 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3408 PF11888.3 CDJ70173.1 - 0.3 11.0 6.2 0.3 11.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CcmH PF03918.9 CDJ70173.1 - 0.34 9.9 5.4 1.2 8.1 3.8 1.7 1 1 0 1 1 1 0 Cytochrome C biogenesis protein PEX11 PF05648.9 CDJ70173.1 - 0.35 10.0 3.4 0.37 10.0 2.4 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Peroxin-13_N PF04088.8 CDJ70173.1 - 0.41 10.6 3.1 0.44 10.4 2.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FLO_LFY PF01698.11 CDJ70173.1 - 0.61 8.8 6.4 0.63 8.8 4.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Suf PF05843.9 CDJ70173.1 - 0.73 9.5 13.9 0.72 9.5 9.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.9 CDJ70173.1 - 0.87 9.1 7.5 0.91 9.1 5.2 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DDHD PF02862.12 CDJ70173.1 - 0.88 9.3 6.6 0.94 9.2 4.6 1.0 1 0 0 1 1 1 0 DDHD domain DUF788 PF05620.6 CDJ70173.1 - 0.89 9.3 9.6 1 9.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Rpp20 PF12328.3 CDJ70173.1 - 0.92 9.1 8.6 1.1 8.8 6.0 1.0 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Gag_spuma PF03276.9 CDJ70173.1 - 1 7.6 19.4 0.94 7.7 13.5 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF912 PF06024.7 CDJ70173.1 - 1 9.4 4.8 1.1 9.2 3.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CDJ70173.1 - 1.2 8.1 20.1 1.3 8.0 13.9 1.0 1 0 0 1 1 1 0 Fms-interacting protein Phage_GPO PF05929.6 CDJ70173.1 - 1.2 8.3 9.3 1.2 8.3 6.4 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3276 PF11680.3 CDJ70173.1 - 1.2 8.9 7.3 1.5 8.6 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Dala_Dala_lig_N PF01820.16 CDJ70173.1 - 1.5 9.1 5.1 1.7 8.9 3.5 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4512 PF14975.1 CDJ70173.1 - 1.6 9.6 5.3 2 9.3 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Band_3_cyto PF07565.8 CDJ70173.1 - 1.6 8.1 9.0 1.6 8.1 6.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 CDJ70173.1 - 1.6 8.5 8.9 1.8 8.3 6.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SprA-related PF12118.3 CDJ70173.1 - 1.6 7.9 24.3 1.6 7.9 16.8 1.0 1 0 0 1 1 1 0 SprA-related family FHIPEP PF00771.15 CDJ70173.1 - 1.7 6.9 7.4 2 6.6 5.1 1.0 1 0 0 1 1 1 0 FHIPEP family Serinc PF03348.10 CDJ70173.1 - 2.1 6.9 9.4 2.4 6.8 6.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2203 PF09969.4 CDJ70173.1 - 2.1 8.5 6.1 2.3 8.4 4.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Kei1 PF08552.6 CDJ70173.1 - 2.2 7.9 5.9 2.2 7.9 4.1 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RNA_lig_T4_1 PF09511.5 CDJ70173.1 - 2.6 7.4 6.1 3.2 7.1 4.2 1.1 1 0 0 1 1 1 0 RNA ligase OATP PF03137.15 CDJ70173.1 - 2.9 5.8 7.0 3 5.8 4.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM176 PF14851.1 CDJ70173.1 - 3.1 7.4 5.3 3.7 7.2 3.7 1.1 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.10 CDJ70173.1 - 3.1 7.8 5.5 3.7 7.6 3.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Rsc14 PF08586.5 CDJ70173.1 - 3.2 8.2 7.7 4.5 7.8 5.3 1.2 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit PAT1 PF09770.4 CDJ70173.1 - 3.3 5.8 26.6 3.2 5.8 18.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AIF_C PF14721.1 CDJ70173.1 - 3.4 7.9 8.5 4 7.7 5.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex14_N PF04695.8 CDJ70173.1 - 3.8 7.5 17.7 4.2 7.4 12.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4199 PF13858.1 CDJ70173.1 - 4.1 7.2 6.1 5.2 6.9 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) AAA_23 PF13476.1 CDJ70173.1 - 4.3 7.6 13.4 4.5 7.5 9.3 1.0 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDJ70173.1 - 4.5 5.3 36.8 4.6 5.3 25.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDJ70173.1 - 5.1 6.9 10.2 5.4 6.8 7.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1764 PF08576.5 CDJ70173.1 - 5.2 7.8 13.6 6 7.7 9.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) zf-DHHC PF01529.15 CDJ70173.1 - 5.9 6.2 6.7 7 6.0 4.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase YfhO PF09586.5 CDJ70173.1 - 6.2 4.7 7.3 6.2 4.6 5.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3260 PF11658.3 CDJ70173.1 - 7 4.6 9.4 7.8 4.5 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF2149 PF09919.4 CDJ70173.1 - 7.5 6.7 8.5 9 6.4 5.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Baculo_PP31 PF05311.6 CDJ70173.1 - 8.6 5.5 11.7 9.6 5.3 8.1 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Suf PF05843.9 CDJ70174.1 - 0.00032 20.5 5.9 0.00032 20.5 4.1 5.8 4 1 1 5 5 5 3 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ70174.1 - 0.0029 17.5 12.1 0.0029 17.5 8.4 7.2 5 2 1 6 6 6 2 Transcription factor IIA, alpha/beta subunit Seryl_tRNA_N PF02403.17 CDJ70175.1 - 0.056 13.4 22.7 1.4 8.9 12.8 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BTV_NS2 PF04514.7 CDJ70175.1 - 0.068 12.0 10.1 0.086 11.7 7.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Mem_trans PF03547.13 CDJ70175.1 - 0.091 11.0 3.5 0.11 10.8 2.4 1.1 1 0 0 1 1 1 0 Membrane transport protein DHHW PF14286.1 CDJ70175.1 - 0.33 10.2 4.6 0.37 10.0 3.2 1.0 1 0 0 1 1 1 0 DHHW protein His_Phos_2 PF00328.17 CDJ70175.1 - 0.34 10.1 8.1 0.41 9.9 5.6 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Med15 PF09606.5 CDJ70175.1 - 0.43 8.7 33.7 0.46 8.6 23.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ70175.1 - 0.78 9.5 20.6 0.84 9.4 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.1 CDJ70175.1 - 0.81 7.3 38.9 1 6.9 27.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PLRV_ORF5 PF01690.12 CDJ70175.1 - 0.89 8.6 7.9 1 8.4 5.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Peroxin-13_N PF04088.8 CDJ70175.1 - 1 9.3 5.5 1.2 9.0 3.5 1.3 1 1 0 1 1 1 0 Peroxin 13, N-terminal region UPF0560 PF10577.4 CDJ70175.1 - 1.2 7.3 13.0 1.4 7.1 9.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Gti1_Pac2 PF09729.4 CDJ70175.1 - 1.3 8.8 6.5 1.7 8.4 4.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SID-1_RNA_chan PF13965.1 CDJ70175.1 - 1.4 7.0 7.1 1.6 6.7 5.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Band_3_cyto PF07565.8 CDJ70175.1 - 1.5 8.2 13.0 1.9 7.9 9.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ctr PF04145.10 CDJ70175.1 - 1.6 8.7 7.0 2.3 8.2 4.8 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Hid1 PF12722.2 CDJ70175.1 - 1.8 6.1 11.3 2 6.0 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 CDJ70175.1 - 2 8.2 11.7 2.4 8.0 8.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vps39_2 PF10367.4 CDJ70175.1 - 2 8.6 10.2 1.1 9.3 5.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 FAM60A PF15396.1 CDJ70175.1 - 2.1 8.0 8.6 2.5 7.8 6.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hom_end_hint PF05203.11 CDJ70175.1 - 2.3 7.9 6.6 2.7 7.6 4.6 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint PAT1 PF09770.4 CDJ70175.1 - 2.4 6.3 26.7 2.6 6.1 18.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S46 PF10459.4 CDJ70175.1 - 2.6 6.3 13.1 3 6.1 9.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Ycf1 PF05758.7 CDJ70175.1 - 3 5.4 9.6 3 5.4 6.7 1.0 1 0 0 1 1 1 0 Ycf1 FimP PF09766.4 CDJ70175.1 - 3.3 6.6 22.1 4.2 6.3 15.0 1.5 1 1 0 1 1 1 0 Fms-interacting protein Mitofilin PF09731.4 CDJ70175.1 - 3.4 6.2 24.6 3.8 6.0 17.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Neur_chan_memb PF02932.11 CDJ70175.1 - 3.9 7.2 7.1 4.2 7.1 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Fib_alpha PF08702.5 CDJ70175.1 - 4.6 7.3 18.4 6.4 6.8 12.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DDHD PF02862.12 CDJ70175.1 - 6.1 6.5 12.2 7.1 6.3 8.5 1.1 1 0 0 1 1 1 0 DDHD domain EIIBC-GUT_N PF03612.9 CDJ70175.1 - 6.8 6.2 7.9 9.3 5.8 5.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DNA_pol_viral_N PF00242.12 CDJ70175.1 - 6.9 5.6 13.6 7.6 5.4 9.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain TraG_N PF07916.6 CDJ70175.1 - 7.9 4.7 13.7 8.6 4.6 9.5 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region APO_RNA-bind PF05634.6 CDJ70175.1 - 8 5.5 8.8 4.3 6.4 4.5 1.6 1 1 1 2 2 2 0 APO RNA-binding APC8 PF04049.8 CDJ70175.1 - 8.1 6.1 13.1 17 5.1 9.1 1.7 1 1 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 Asp-B-Hydro_N PF05279.6 CDJ70175.1 - 8.4 6.1 11.9 9.8 5.9 8.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3533 PF12051.3 CDJ70175.1 - 9.2 4.8 6.8 10 4.7 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF3381 PF11861.3 CDJ70175.1 - 9.3 5.7 20.5 4.6 6.7 12.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DDRGK PF09756.4 CDJ70177.1 - 0.073 12.4 7.6 0.069 12.5 5.3 1.2 1 0 0 1 1 1 0 DDRGK domain DUF4175 PF13779.1 CDJ70177.1 - 0.16 9.6 27.2 0.14 9.7 18.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt5_N PF11942.3 CDJ70177.1 - 0.2 12.2 7.2 0.27 11.8 5.0 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Cwf_Cwc_15 PF04889.7 CDJ70177.1 - 0.32 10.6 12.3 0.37 10.4 8.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SpoIIIAH PF12685.2 CDJ70177.1 - 0.33 10.4 11.1 0.37 10.2 7.7 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Sporozoite_P67 PF05642.6 CDJ70177.1 - 0.35 8.6 5.8 0.41 8.4 4.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_G7 PF05503.7 CDJ70177.1 - 0.35 9.4 2.5 0.38 9.3 1.7 1.0 1 0 0 1 1 1 0 Poxvirus G7-like SAGA-Tad1 PF12767.2 CDJ70177.1 - 0.36 10.4 17.4 0.44 10.1 12.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Med15 PF09606.5 CDJ70177.1 - 0.43 8.7 35.4 0.45 8.6 24.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.1 CDJ70177.1 - 0.51 9.2 9.5 0.58 9.0 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Plasmodium_Vir PF05795.6 CDJ70177.1 - 0.75 8.9 8.2 0.85 8.7 5.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM51 PF15345.1 CDJ70177.1 - 0.76 9.4 17.5 0.96 9.0 12.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Apc15p PF05841.6 CDJ70177.1 - 0.83 10.3 19.5 1 10.1 13.5 1.1 1 0 0 1 1 1 0 Apc15p protein FAM60A PF15396.1 CDJ70177.1 - 1.1 8.9 15.2 1.3 8.6 10.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Spc7_N PF15402.1 CDJ70177.1 - 1.6 6.6 22.3 2 6.3 15.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FAM176 PF14851.1 CDJ70177.1 - 1.6 8.3 8.5 2.3 7.9 5.9 1.2 1 0 0 1 1 1 0 FAM176 family Myco_19_kDa PF05481.7 CDJ70177.1 - 1.7 8.4 6.6 2.5 7.8 4.6 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen FHIPEP PF00771.15 CDJ70177.1 - 1.8 6.7 6.3 2 6.6 4.4 1.0 1 0 0 1 1 1 0 FHIPEP family DHHW PF14286.1 CDJ70177.1 - 1.8 7.7 8.2 2.3 7.4 5.7 1.1 1 0 0 1 1 1 0 DHHW protein USP8_interact PF08941.5 CDJ70177.1 - 2 7.7 7.2 2.3 7.4 5.0 1.2 1 0 0 1 1 1 0 USP8 interacting PAT1 PF09770.4 CDJ70177.1 - 2.2 6.3 33.2 2.3 6.3 23.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SUFU_C PF12470.3 CDJ70177.1 - 2.4 7.6 8.3 3 7.3 5.7 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Borrelia_P83 PF05262.6 CDJ70177.1 - 3.5 5.7 9.8 3.4 5.8 6.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RAP1 PF07218.6 CDJ70177.1 - 3.6 5.5 5.0 3.3 5.6 3.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3513 PF12026.3 CDJ70177.1 - 4.3 6.8 16.4 5.1 6.5 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Nucleo_P87 PF07267.6 CDJ70177.1 - 6.9 5.2 13.6 6.9 5.2 9.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Lin-8 PF03353.10 CDJ70177.1 - 6.9 5.8 16.4 8.5 5.5 11.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4199 PF13858.1 CDJ70177.1 - 7.4 6.4 5.5 8.6 6.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Totivirus_coat PF05518.6 CDJ70177.1 - 7.6 4.2 9.3 7.8 4.1 6.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF853 PF05872.7 CDJ70177.1 - 7.8 4.7 8.6 8 4.6 6.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3154 PF11351.3 CDJ70177.1 - 8.1 6.2 7.2 12 5.6 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) CDK5_activator PF03261.10 CDJ70177.1 - 8.3 5.6 16.3 9.6 5.4 11.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SLD3 PF08639.5 CDJ70177.1 - 8.8 4.8 24.6 10 4.5 17.1 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 FLO_LFY PF01698.11 CDJ70177.1 - 9.3 4.9 10.3 11 4.7 7.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Membralin PF09746.4 CDJ70177.1 - 9.6 5.1 6.1 11 4.9 4.3 1.0 1 0 0 1 1 1 0 Tumour-associated protein vMSA PF00695.14 CDJ70177.1 - 9.6 5.2 9.0 9.9 5.2 6.3 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Ribosomal_L28e PF01778.12 CDJ70178.1 - 4.8e-26 91.4 0.4 4.8e-26 91.4 0.3 2.3 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.9 CDJ70178.1 - 1.5e-12 47.5 11.3 1.5e-12 47.5 7.8 2.8 1 1 1 2 2 2 1 Mak16 protein C-terminal region Na_trans_assoc PF06512.8 CDJ70178.1 - 0.34 10.8 11.5 0.52 10.2 8.0 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Activator_LAG-3 PF11498.3 CDJ70179.1 - 0.00084 18.2 16.9 0.00084 18.2 11.7 3.2 2 1 0 2 2 2 1 Transcriptional activator LAG-3 PrsW-protease PF13367.1 CDJ70179.1 - 0.0034 16.5 21.2 0.0057 15.8 7.9 3.8 3 1 0 3 3 3 2 Protease prsW family Pkinase PF00069.20 CDJ70180.1 - 1.6e-68 230.6 0.5 3.3e-68 229.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ70180.1 - 7.4e-33 113.7 0.0 1.6e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCHC_6 PF15288.1 CDJ70180.1 - 0.042 13.5 0.0 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 CDJ70181.1 - 4.9e-08 32.5 11.8 3.8e-06 26.5 1.5 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ70181.1 - 0.0011 18.6 0.6 0.0011 18.6 0.4 2.5 1 1 1 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ70181.1 - 0.0034 17.0 0.6 0.0034 17.0 0.4 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ70181.1 - 0.021 14.5 8.1 0.056 13.1 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ70181.1 - 0.021 14.8 8.1 0.046 13.7 5.6 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.1 CDJ70181.1 - 0.047 13.1 3.8 0.089 12.2 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.12 CDJ70181.1 - 0.097 12.7 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Mtr2 PF10429.4 CDJ70181.1 - 0.12 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Asp_protease_2 PF13650.1 CDJ70182.1 - 3.6e-11 43.4 0.0 6.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ70182.1 - 3.2e-08 33.2 0.0 7.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ70182.1 - 2.1e-06 27.5 0.0 5.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ70182.1 - 2e-05 24.5 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDJ70182.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.22 CDJ70183.1 - 9.8e-16 57.7 0.1 2e-15 56.7 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAM92 PF06730.6 CDJ70183.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 FAM92 protein Hexokinase_1 PF00349.16 CDJ70184.1 - 7.1e-59 198.5 0.0 1.2e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CDJ70184.1 - 2e-05 23.9 0.1 2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Hexokinase DUF2009 PF09418.5 CDJ70185.1 - 9.6e-100 334.5 3.8 3e-66 224.1 0.0 4.0 2 2 1 3 3 3 3 Protein of unknown function (DUF2009) DUF755 PF05501.6 CDJ70185.1 - 0.0036 17.3 7.7 0.0036 17.3 5.3 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF755) DUF2217 PF10265.4 CDJ70185.1 - 7.6 5.1 18.0 1.9 7.1 5.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) DUF1777 PF08648.7 CDJ70186.1 - 0.16 11.6 20.5 0.21 11.3 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF778 PF05608.7 CDJ70186.1 - 0.8 9.6 3.4 1 9.3 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF778) CDC45 PF02724.9 CDJ70186.1 - 4.7 5.1 20.9 6.6 4.6 14.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 CDJ70186.1 - 9.2 6.0 36.0 12 5.6 24.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.1 CDJ70187.1 - 0.00025 20.8 0.1 0.00031 20.5 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 OAD_gamma PF04277.8 CDJ70187.1 - 0.0051 17.1 0.0 0.009 16.3 0.0 1.5 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain DUF3328 PF11807.3 CDJ70187.1 - 0.041 13.5 0.2 0.048 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) SecG PF03840.9 CDJ70187.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Preprotein translocase SecG subunit EphA2_TM PF14575.1 CDJ70187.1 - 0.14 12.5 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_60s PF00428.14 CDJ70187.1 - 0.59 10.5 6.3 1.4 9.3 4.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein COX15-CtaA PF02628.10 CDJ70188.1 - 1.5e-24 86.4 2.8 1.8e-24 86.1 2.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosomal_60s PF00428.14 CDJ70188.1 - 0.0051 17.1 9.1 0.0077 16.5 6.3 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF773 PF05600.7 CDJ70189.1 - 4.8e-22 78.4 35.8 4.8e-22 78.4 24.8 4.1 2 2 0 2 2 2 1 Protein of unknown function (DUF773) Androgen_recep PF02166.11 CDJ70189.1 - 0.0033 16.3 2.5 0.0033 16.3 1.7 4.6 5 1 1 6 6 6 2 Androgen receptor Plasmodium_Vir PF05795.6 CDJ70189.1 - 0.38 9.9 1.5 0.93 8.6 0.3 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein EF-hand_1 PF00036.27 CDJ70190.1 - 1.1e-22 77.5 9.2 1.6e-08 33.2 1.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CDJ70190.1 - 1.1e-19 68.5 5.6 2.9e-06 26.6 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CDJ70190.1 - 1.4e-18 66.7 6.3 5.6e-13 48.8 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDJ70190.1 - 7.5e-17 60.6 8.2 1.8e-12 46.6 0.7 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CDJ70190.1 - 1.1e-13 49.8 6.8 1.1e-05 24.5 0.5 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CDJ70190.1 - 2.5e-09 36.9 0.2 1e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.1 CDJ70190.1 - 0.0034 17.0 3.3 0.0078 15.8 0.1 2.2 2 0 0 2 2 2 1 EF hand plasmid_Toxin PF12703.2 CDJ70190.1 - 0.016 14.9 0.1 0.039 13.7 0.1 1.7 1 1 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system EF-hand_4 PF12763.2 CDJ70190.1 - 0.018 14.7 1.7 0.42 10.3 0.5 2.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.12 CDJ70190.1 - 0.019 15.2 1.3 0.034 14.4 0.9 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain SHOCT PF09851.4 CDJ70190.1 - 0.021 14.2 4.4 0.26 10.8 0.1 3.1 3 0 0 3 3 3 0 Short C-terminal domain Rhamno_transf PF11316.3 CDJ70190.1 - 0.035 13.2 0.4 0.041 13.0 0.3 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF1857 PF08982.6 CDJ70192.1 - 0.024 14.2 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) DUF2458 PF10454.4 CDJ70192.1 - 0.62 9.9 15.5 0.8 9.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) DUF755 PF05501.6 CDJ70193.1 - 0.76 9.8 35.8 0.26 11.3 6.3 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF755) Abhydrolase_6 PF12697.2 CDJ70195.1 - 0.042 13.7 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family CSS-motif PF12792.2 CDJ70195.1 - 0.32 10.3 2.9 4 6.7 0.1 2.6 2 0 0 2 2 2 0 CSS motif domain associated with EAL DUF883 PF05957.8 CDJ70195.1 - 4.4 7.7 18.6 3.7 8.0 0.4 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) MBF1 PF08523.5 CDJ70197.1 - 1.9e-18 66.2 1.0 1.9e-18 66.2 0.7 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CDJ70197.1 - 6.7e-15 54.6 0.1 1.1e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 CDJ70197.1 - 1.8e-09 37.5 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CDJ70197.1 - 1.2e-07 31.8 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 CDJ70197.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 CDJ70197.1 - 0.012 15.7 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.1 CDJ70197.1 - 0.053 13.1 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.1 CDJ70197.1 - 0.062 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0203 PF05254.7 CDJ70198.1 - 0.0063 16.3 0.0 0.0066 16.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Transketolase_N PF00456.16 CDJ70199.1 - 8.6e-141 468.5 0.0 3e-140 466.7 0.0 1.7 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CDJ70199.1 - 1.4e-36 125.6 0.0 2.3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 CDJ70199.1 - 5.2e-05 22.3 0.0 0.00028 19.8 0.0 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 CDJ70199.1 - 5.2e-05 23.1 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 CDJ70199.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF2215 PF10225.4 CDJ70207.1 - 0.18 11.2 4.0 0.24 10.8 2.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) IncA PF04156.9 CDJ70207.1 - 0.21 11.1 24.4 0.3 10.6 16.9 1.2 1 0 0 1 1 1 0 IncA protein DUF2217 PF10265.4 CDJ70207.1 - 0.28 9.9 14.8 0.33 9.6 10.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Alpha_GJ PF03229.8 CDJ70207.1 - 7.8 6.8 25.4 1.8 8.9 1.6 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J Ebola_NP PF05505.7 CDJ70207.1 - 7.9 4.4 19.9 9.4 4.1 13.8 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein AAA_23 PF13476.1 CDJ70209.1 - 0.1 12.9 0.1 0.1 12.9 0.1 6.4 3 2 0 3 3 3 0 AAA domain RTBV_P46 PF06216.6 CDJ70209.1 - 1.3 7.8 5.4 0.67 8.7 0.6 2.4 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein IncA PF04156.9 CDJ70210.1 - 0.0021 17.6 5.8 0.0021 17.6 4.1 3.2 3 0 0 3 3 3 1 IncA protein Spt20 PF12090.3 CDJ70210.1 - 0.19 11.0 11.4 1.8 7.8 0.4 2.4 2 0 0 2 2 2 0 Spt20 family Ycf1 PF05758.7 CDJ70210.1 - 0.89 7.1 4.7 2.5 5.7 0.0 2.0 2 0 0 2 2 2 0 Ycf1 Pex16 PF08610.5 CDJ70210.1 - 1.1 8.1 9.5 2.4 7.0 0.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) DUF4557 PF15101.1 CDJ70210.1 - 1.2 8.9 22.5 0.3 10.8 4.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) dsDNA_bind PF01984.15 CDJ70210.1 - 7.1 6.6 30.0 0.15 12.0 6.2 2.4 2 0 0 2 2 2 0 Double-stranded DNA-binding domain LCD1 PF09798.4 CDJ70210.1 - 7.2 4.4 10.9 1.6 6.6 0.4 2.0 2 0 0 2 2 2 0 DNA damage checkpoint protein DUF830 PF05708.7 CDJ70213.1 - 0.0021 18.0 0.9 0.0074 16.2 0.0 2.2 2 0 0 2 2 2 1 Orthopoxvirus protein of unknown function (DUF830) DUF755 PF05501.6 CDJ70213.1 - 0.0022 18.0 17.0 0.0022 18.0 11.8 5.5 3 2 1 4 4 4 1 Domain of unknown function (DUF755) DUF605 PF04652.11 CDJ70213.1 - 5.4 6.3 62.7 0.092 12.1 32.3 2.1 2 0 0 2 2 2 0 Vta1 like hDGE_amylase PF14701.1 CDJ70214.1 - 3.9 6.2 17.5 5.6 5.7 12.1 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Ndc1_Nup PF09531.5 CDJ70215.1 - 0.23 9.8 8.7 0.29 9.4 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Plasmodium_Vir PF05795.6 CDJ70215.1 - 0.36 9.9 2.5 0.5 9.5 1.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.2 CDJ70215.1 - 6.6 4.2 7.3 8.7 3.8 5.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pap_E4 PF02711.9 CDJ70216.1 - 0.13 13.0 0.2 0.13 13.0 0.1 6.3 4 1 2 6 6 6 0 E4 protein Telomerase_RBD PF12009.3 CDJ70217.1 - 1.4e-21 76.8 0.5 1.8e-14 53.8 0.9 4.1 3 1 0 3 3 3 2 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CDJ70217.1 - 0.0041 16.5 3.6 2.3 7.4 0.0 3.5 4 0 0 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_UL87 PF03043.9 CDJ70217.1 - 0.015 13.7 11.7 37 2.5 0.0 3.6 3 1 0 3 3 3 0 Herpesvirus UL87 family Dehydrin PF00257.14 CDJ70217.1 - 0.7 10.2 0.0 0.7 10.2 0.0 11.4 9 4 0 9 9 9 0 Dehydrin RVT_1 PF00078.22 CDJ70218.1 - 0.00046 19.6 0.0 0.82 8.9 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Suf PF05843.9 CDJ70218.1 - 0.012 15.3 13.6 0.062 13.0 4.4 2.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDJ70218.1 - 0.44 9.8 56.1 0.37 10.1 7.5 3.2 3 0 0 3 3 3 0 Vta1 like Zip PF02535.17 CDJ70218.1 - 9 5.1 9.7 17 4.3 5.9 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Fmp27_WPPW PF10359.4 CDJ70221.1 - 8.4 4.6 18.2 0.021 13.2 0.6 2.4 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain Ribosomal_60s PF00428.14 CDJ70222.1 - 0.0037 17.6 5.7 0.0037 17.6 4.0 1.6 2 0 0 2 2 2 1 60s Acidic ribosomal protein DEAD PF00270.24 CDJ70224.1 - 2.1e-22 79.4 0.0 3.2e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDC45 PF02724.9 CDJ70225.1 - 0.0033 15.5 0.1 0.0037 15.3 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein TRP PF06011.7 CDJ70225.1 - 0.042 12.4 0.0 0.045 12.3 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Kei1 PF08552.6 CDJ70225.1 - 0.11 12.1 3.1 0.38 10.3 1.7 1.9 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 LMBR1 PF04791.11 CDJ70225.1 - 0.15 10.5 0.4 0.17 10.4 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 CDJ70225.1 - 0.29 10.9 3.9 0.34 10.7 2.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2477 PF10631.4 CDJ70225.1 - 1.6 8.9 32.5 0.061 13.5 17.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) Pinin_SDK_memA PF04696.8 CDJ70225.1 - 2 8.0 22.8 3.1 7.4 15.8 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF2371 PF10177.4 CDJ70225.1 - 2.3 8.1 5.4 4.7 7.0 3.8 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) BRF1 PF07741.8 CDJ70225.1 - 2.9 8.1 12.7 0.23 11.6 5.3 1.7 2 0 0 2 2 2 0 Brf1-like TBP-binding domain OSTbeta PF15048.1 CDJ70225.1 - 4 7.5 9.2 5 7.2 5.8 1.6 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF4652 PF15525.1 CDJ70225.1 - 4.3 6.7 10.2 5.8 6.2 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Prp31_C PF09785.4 CDJ70225.1 - 5.6 7.4 15.8 9.8 6.6 11.0 1.4 1 0 0 1 1 1 0 Prp31 C terminal domain DUF1980 PF09323.5 CDJ70225.1 - 5.8 6.6 11.8 90 2.7 9.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Glyco_transf_15 PF01793.11 CDJ70225.1 - 7 5.4 9.4 9.6 5.0 6.5 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase NARP1 PF12569.3 CDJ70225.1 - 7.8 5.1 12.6 11 4.6 8.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF913 PF06025.7 CDJ70225.1 - 8.7 4.9 9.1 0.23 10.1 2.0 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DEAD PF00270.24 CDJ70226.1 - 2.7e-27 95.2 17.6 1.8e-23 82.8 1.2 4.9 5 0 0 5 5 5 2 DEAD/DEAH box helicase DUF3446 PF11928.3 CDJ70226.1 - 0.015 15.4 2.9 0.015 15.4 2.0 5.8 4 1 0 4 4 4 0 Domain of unknown function (DUF3446) Asp-B-Hydro_N PF05279.6 CDJ70227.1 - 0.82 9.4 13.0 1.1 9.1 9.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Utp14 PF04615.8 CDJ70227.1 - 7.4 4.6 22.6 9.2 4.2 15.7 1.1 1 0 0 1 1 1 0 Utp14 protein SR-25 PF10500.4 CDJ70229.1 - 0.0012 18.4 43.4 0.055 12.9 10.5 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.8 CDJ70229.1 - 0.023 15.0 9.4 0.023 15.0 6.5 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain CDC45 PF02724.9 CDJ70229.1 - 0.19 9.6 12.8 0.23 9.4 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Dot_icm_IcmQ PF09475.5 CDJ70229.1 - 1.4 8.1 5.2 0.19 10.9 0.9 1.5 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Ald_Xan_dh_C2 PF02738.13 CDJ70229.1 - 2.4 6.3 14.5 0.52 8.5 1.2 2.0 1 1 1 2 2 2 0 Molybdopterin-binding domain of aldehyde dehydrogenase PHD_3 PF13922.1 CDJ70229.1 - 3.1 8.1 13.5 24 5.2 6.5 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx FimP PF09766.4 CDJ70229.1 - 3.5 6.6 13.9 0.49 9.3 4.7 2.0 2 0 0 2 2 2 0 Fms-interacting protein Asp_protease_2 PF13650.1 CDJ70231.1 - 1.4e-09 38.3 0.0 2.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 CDJ70231.1 - 2.2e-08 33.6 10.6 2.7e-06 27.0 1.2 2.6 2 0 0 2 2 2 2 Zinc knuckle gag-asp_proteas PF13975.1 CDJ70231.1 - 2e-07 30.7 0.0 5.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ70231.1 - 4.6e-06 26.4 0.0 1.4e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ70231.1 - 0.00023 21.1 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 CDJ70231.1 - 0.00075 19.1 5.3 0.016 14.9 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ70231.1 - 0.012 15.3 0.5 0.012 15.3 0.3 2.6 1 1 1 2 2 2 0 Zinc knuckle Asp_protease PF09668.5 CDJ70231.1 - 0.038 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_6 PF15288.1 CDJ70231.1 - 0.04 13.5 0.6 0.04 13.5 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 CDJ70231.1 - 0.055 12.9 3.5 0.071 12.6 0.2 2.4 1 1 1 2 2 2 0 Zinc knuckle Med3 PF11593.3 CDJ70232.1 - 1.2 8.2 9.4 1.4 8.0 6.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NUDE_C PF04880.8 CDJ70232.1 - 6.5 7.0 13.3 6.1e+02 0.6 9.2 2.1 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF4614 PF15391.1 CDJ70233.1 - 0.14 11.9 12.3 1.2 8.8 6.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) ATG16 PF08614.6 CDJ70233.1 - 0.15 11.8 7.0 0.11 12.3 1.0 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Period_C PF12114.3 CDJ70233.1 - 0.48 10.0 16.5 1 8.9 11.4 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Apt1 PF10351.4 CDJ70233.1 - 1.3 7.8 12.3 2.3 6.9 8.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SSP160 PF06933.6 CDJ70233.1 - 4.8 5.0 16.1 7.1 4.4 11.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DDHD PF02862.12 CDJ70233.1 - 8 6.1 11.4 26 4.4 7.9 1.8 1 1 0 1 1 1 0 DDHD domain DUF2722 PF10846.3 CDJ70234.1 - 0.0028 16.7 0.9 0.0028 16.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RNA_pol_Rpb4 PF03874.11 CDJ70234.1 - 0.064 13.2 0.5 0.14 12.1 0.3 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb4 Pex14_N PF04695.8 CDJ70234.1 - 0.22 11.5 4.9 0.26 11.3 3.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med13_N PF11597.3 CDJ70234.1 - 0.74 8.4 3.5 0.97 8.0 2.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Med15 PF09606.5 CDJ70234.1 - 1.1 7.4 23.9 1.1 7.3 16.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ70234.1 - 2.6 7.3 9.5 3.1 7.0 6.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF4175 PF13779.1 CDJ70234.1 - 4.5 4.8 20.4 4.9 4.7 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Activator_LAG-3 PF11498.3 CDJ70234.1 - 7.4 5.1 30.4 8.3 5.0 21.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CDJ70234.1 - 8.2 6.0 11.3 9.7 5.8 7.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDJ70234.1 - 9 4.3 18.4 10 4.2 12.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Isochorismatase PF00857.15 CDJ70235.1 - 1.9e-27 96.3 0.8 4.1e-20 72.4 0.4 2.2 2 0 0 2 2 2 2 Isochorismatase family Dynein_light PF01221.13 CDJ70237.1 - 9.8e-44 147.2 0.4 1.1e-43 147.1 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Helicase_C PF00271.26 CDJ70238.1 - 1.7e-14 53.4 0.3 1.4e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CDJ70238.1 - 1.5e-13 50.0 0.2 8.2e-13 47.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) FUSC PF04632.7 CDJ70238.1 - 4.1 5.7 7.9 5 5.4 5.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Methyltransf_23 PF13489.1 CDJ70239.1 - 1.3e-05 24.9 0.0 1.3e-05 24.9 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDJ70239.1 - 6.3e-05 22.6 8.4 0.0028 17.2 0.2 3.2 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_26 PF13659.1 CDJ70239.1 - 0.00021 21.2 8.0 0.00021 21.2 5.5 3.8 2 2 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDJ70239.1 - 0.00023 21.5 7.1 0.00098 19.5 0.4 3.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDJ70239.1 - 0.0005 20.6 2.8 0.0005 20.6 1.9 3.2 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDJ70239.1 - 0.017 15.5 0.1 0.017 15.5 0.1 3.6 3 1 0 3 3 3 0 Methyltransferase domain Nucleoside_tran PF01733.13 CDJ70239.1 - 0.09 11.9 1.2 0.16 11.0 0.8 1.3 1 0 0 1 1 1 0 Nucleoside transporter Methyltransf_24 PF13578.1 CDJ70239.1 - 0.22 12.3 0.8 1 10.2 0.3 2.6 2 1 0 2 2 1 0 Methyltransferase domain Abhydrolase_4 PF08386.5 CDJ70239.1 - 2.1 8.2 9.9 0.12 12.2 0.7 3.0 2 1 0 2 2 2 0 TAP-like protein PrmA PF06325.8 CDJ70239.1 - 3.7 6.5 10.9 0.058 12.4 0.7 2.3 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DUF572 PF04502.8 CDJ70239.1 - 6.2 5.9 20.2 12 4.9 14.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3617 PF12276.3 CDJ70240.1 - 0.0057 16.1 0.3 0.0057 16.1 0.2 9.1 7 3 0 7 7 7 1 Protein of unknown function (DUF3617) RCR PF12273.3 CDJ70240.1 - 0.0095 16.4 4.3 0.0095 16.4 3.0 7.3 6 2 0 6 6 6 1 Chitin synthesis regulation, resistance to Congo red Semialdhyde_dhC PF02774.13 CDJ70242.1 - 0.16 11.8 0.1 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain LSM PF01423.17 CDJ70243.1 - 6.4e-18 64.0 0.0 8e-18 63.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain MRP-L46 PF11788.3 CDJ70244.1 - 0.035 14.7 7.0 0.15 12.7 3.4 2.3 1 1 1 2 2 2 0 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 CDJ70244.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Prenyltrans PF00432.16 CDJ70245.1 - 3.5e-22 77.6 19.3 1e-09 37.7 0.0 8.3 8 1 0 8 8 8 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CDJ70245.1 - 1.5e-14 54.3 0.1 1.5e-07 31.7 0.0 5.6 4 1 1 5 5 5 3 Prenyltransferase-like MAR_sialic_bdg PF10564.4 CDJ70246.1 - 5.8e-82 269.7 37.1 2.1e-24 85.1 4.6 4.3 4 0 0 4 4 4 4 Sialic-acid binding micronemal adhesive repeat DSL PF01414.14 CDJ70246.1 - 0.0071 16.3 6.1 2.6 8.1 0.1 3.9 3 0 0 3 3 3 2 Delta serrate ligand MAR_sialic_bdg PF10564.4 CDJ70249.1 - 9.8e-18 63.7 1.1 1.4e-17 63.2 0.7 1.2 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat E1_dh PF00676.15 CDJ70250.1 - 1e-94 316.6 0.0 1.3e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 CDJ70250.1 - 2.8e-11 43.2 0.2 6.2e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 CDJ70250.1 - 6.9e-07 28.3 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CDJ70250.1 - 2.1e-05 23.5 0.0 3.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Ocnus PF05005.10 CDJ70251.1 - 1.2e-18 66.9 0.2 2.3e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) DUF2205 PF10224.4 CDJ70252.1 - 0.037 13.5 0.1 0.037 13.5 0.1 3.0 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) RadC PF04002.10 CDJ70252.1 - 0.067 12.8 0.4 0.26 10.9 0.2 1.9 2 0 0 2 2 2 0 RadC-like JAB domain Vac_Fusion PF02346.11 CDJ70252.1 - 0.083 12.3 0.2 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus fusion protein DUF241 PF03087.9 CDJ70252.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.6 2 1 0 2 2 2 0 Arabidopsis protein of unknown function Occludin_ELL PF07303.8 CDJ70252.1 - 0.17 12.5 0.2 0.17 12.5 0.1 2.8 3 0 0 3 3 3 0 Occludin homology domain Seryl_tRNA_N PF02403.17 CDJ70252.1 - 0.48 10.4 13.1 1.8 8.6 0.0 3.8 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.6 CDJ70252.1 - 0.48 10.8 0.0 0.48 10.8 0.0 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal MscS_porin PF12795.2 CDJ70252.1 - 0.52 9.5 12.1 0.068 12.4 3.8 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Myc_N PF01056.13 CDJ70252.1 - 2.4 7.2 12.9 4.3 6.4 9.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Wyosine_form PF08608.7 CDJ70253.1 - 1.6e-19 69.7 0.0 4.2e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 CDJ70253.1 - 4.7e-15 56.1 0.0 9.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily CMD PF02627.15 CDJ70253.1 - 0.02 14.7 0.1 0.068 13.0 0.1 1.9 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family HAD_2 PF13419.1 CDJ70253.1 - 0.17 12.1 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DNA_ligase_aden PF01653.13 CDJ70254.1 - 9.3e-39 133.2 0.0 1.7e-11 43.6 0.0 5.8 3 1 1 4 4 4 4 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.11 CDJ70254.1 - 2.8e-23 81.3 0.1 5.3e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_5 PF14520.1 CDJ70254.1 - 0.015 15.4 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain B56 PF01603.15 CDJ70255.1 - 1.3e-144 481.7 4.8 1.8e-144 481.3 3.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) CAP PF00188.21 CDJ70258.1 - 1.4e-07 32.0 2.2 1.2e-06 29.0 1.5 2.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family TSP_1 PF00090.14 CDJ70258.1 - 0.0084 16.2 6.9 0.0084 16.2 4.8 5.2 5 1 0 5 5 5 1 Thrombospondin type 1 domain SR-25 PF10500.4 CDJ70259.1 - 0.0027 17.1 23.1 0.0027 17.1 16.0 3.9 3 2 0 3 3 3 1 Nuclear RNA-splicing-associated protein Pox_F12L PF03337.8 CDJ70259.1 - 0.17 9.7 0.5 0.25 9.2 0.3 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein ATP-synt PF00231.14 CDJ70260.1 - 8.8e-23 81.0 0.0 1.6e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 ATP synthase DUF3457 PF11939.3 CDJ70260.1 - 0.066 12.7 0.3 0.066 12.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3457) Ribosomal_60s PF00428.14 CDJ70260.1 - 0.069 13.5 31.9 0.71 10.3 5.0 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3357 PF11837.3 CDJ70260.1 - 0.21 11.4 1.0 2.4 8.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Sarcoglycan_1 PF04790.8 CDJ70260.1 - 0.3 10.2 0.9 0.46 9.6 0.6 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein DUF3357 PF11837.3 CDJ70262.1 - 0.0024 17.6 0.9 0.0031 17.3 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Suf PF05843.9 CDJ70262.1 - 0.012 15.3 16.0 0.014 15.1 11.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NifQ PF04891.7 CDJ70262.1 - 0.092 12.9 6.4 0.11 12.6 4.5 1.2 1 0 0 1 1 1 0 NifQ DUF2370 PF10176.4 CDJ70262.1 - 0.11 11.7 3.4 0.14 11.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Zip PF02535.17 CDJ70262.1 - 0.17 10.8 2.4 0.2 10.6 1.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 CDJ70262.1 - 0.28 10.0 12.1 0.31 9.8 8.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein ARGLU PF15346.1 CDJ70262.1 - 0.29 10.8 23.8 0.37 10.5 16.5 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 SAGA-Tad1 PF12767.2 CDJ70262.1 - 0.45 10.1 15.8 0.51 9.9 11.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AUX_IAA PF02309.11 CDJ70262.1 - 0.6 9.8 10.6 0.73 9.5 7.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Trp_oprn_chp PF09534.5 CDJ70262.1 - 0.68 9.5 6.4 0.84 9.2 4.4 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAM60A PF15396.1 CDJ70262.1 - 0.74 9.5 11.1 0.88 9.2 7.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF1675 PF07897.6 CDJ70262.1 - 1.3 8.7 8.8 1.5 8.6 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2076 PF09849.4 CDJ70262.1 - 1.5 8.8 30.0 1.7 8.6 20.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HCO3_cotransp PF00955.16 CDJ70262.1 - 1.5 7.3 5.8 1.7 7.2 4.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family SPX PF03105.14 CDJ70262.1 - 1.6 8.4 11.7 1.7 8.3 8.1 1.0 1 0 0 1 1 1 0 SPX domain eIF-3_zeta PF05091.7 CDJ70262.1 - 1.7 7.1 15.7 1.9 7.0 10.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.8 CDJ70262.1 - 2.2 7.7 15.8 2.7 7.4 10.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDRGK PF09756.4 CDJ70262.1 - 2.9 7.2 17.2 4.3 6.7 11.9 1.3 1 0 0 1 1 1 0 DDRGK domain DUF45 PF01863.12 CDJ70262.1 - 3.3 7.4 11.3 3.9 7.2 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 MDFI PF15316.1 CDJ70262.1 - 3.5 7.5 8.1 4.5 7.2 5.6 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Allexi_40kDa PF05549.6 CDJ70262.1 - 3.7 6.7 9.8 4.1 6.6 6.8 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spore_coat_CotO PF14153.1 CDJ70262.1 - 4.2 6.7 20.9 5.1 6.4 14.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CemA PF03040.9 CDJ70262.1 - 4.4 6.8 13.6 5.2 6.6 9.4 1.0 1 0 0 1 1 1 0 CemA family PAT1 PF09770.4 CDJ70262.1 - 4.9 5.2 37.9 5.7 5.0 26.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CD20 PF04103.10 CDJ70262.1 - 5.3 6.9 5.3 7.5 6.4 3.7 1.3 1 1 0 1 1 1 0 CD20-like family Rtf2 PF04641.7 CDJ70262.1 - 5.6 6.0 15.7 6.7 5.8 10.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3449 PF11931.3 CDJ70262.1 - 5.8 6.3 13.0 6.9 6.1 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Presenilin PF01080.12 CDJ70262.1 - 6.4 5.4 9.0 7.2 5.3 6.3 1.0 1 0 0 1 1 1 0 Presenilin DUF853 PF05872.7 CDJ70262.1 - 6.6 4.9 12.6 9.3 4.4 8.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Neur_chan_memb PF02932.11 CDJ70262.1 - 6.9 6.4 11.3 8.6 6.1 7.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hepcidin PF06446.7 CDJ70262.1 - 9.5 6.7 9.0 4.1 7.8 2.3 2.2 2 0 0 2 2 2 0 Hepcidin Shikimate_dh_N PF08501.6 CDJ70263.1 - 2.2e-10 40.4 0.0 3.7e-09 36.5 0.0 2.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CDJ70263.1 - 1.5e-05 25.1 1.5 0.0048 16.9 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase SR-25 PF10500.4 CDJ70263.1 - 0.0047 16.4 4.3 0.0047 16.4 3.0 9.5 9 1 0 9 9 9 1 Nuclear RNA-splicing-associated protein APG9 PF04109.11 CDJ70263.1 - 0.045 12.6 0.0 0.16 10.8 0.0 1.9 1 0 0 1 1 1 0 Autophagy protein Apg9 SKI PF01202.17 CDJ70263.1 - 0.94 9.3 11.6 15 5.3 0.0 5.2 4 1 1 5 5 5 0 Shikimate kinase Med15 PF09606.5 CDJ70264.1 - 0.0015 16.8 54.5 0.0022 16.3 37.7 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Rad4 PF03835.10 CDJ70264.1 - 0.019 14.3 0.1 0.019 14.3 0.0 2.3 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain Ndc1_Nup PF09531.5 CDJ70264.1 - 0.51 8.6 11.8 0.89 7.9 8.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.7 CDJ70264.1 - 4.9 6.9 13.7 9.9 5.9 9.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_UL87 PF03043.9 CDJ70264.1 - 5.1 5.3 7.2 7.6 4.7 5.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Dicty_REP PF05086.7 CDJ70264.1 - 5.3 4.6 5.0 7.8 4.1 3.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC27 PF09507.5 CDJ70264.1 - 6.2 5.9 25.6 0.56 9.3 13.9 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Med15 PF09606.5 CDJ70265.1 - 0.00076 17.8 46.3 0.00076 17.8 32.1 3.0 2 1 1 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Exo_endo_phos PF03372.18 CDJ70269.1 - 6.7e-19 68.7 0.0 1.5e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PPP4R2 PF09184.6 CDJ70270.1 - 1.2e-06 28.3 6.8 1.2e-06 28.3 4.7 2.3 2 1 0 2 2 2 1 PPP4R2 SR-25 PF10500.4 CDJ70270.1 - 0.29 10.5 34.0 0.094 12.1 8.8 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.8 CDJ70270.1 - 1.3 8.8 47.1 0.3 10.9 9.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 CDJ70270.1 - 3.9 5.3 22.9 3.1 5.7 10.6 2.1 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_viral_N PF00242.12 CDJ70270.1 - 6 5.7 30.8 0.043 12.8 4.7 2.2 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain DUF2749 PF10907.3 CDJ70271.1 - 0.16 11.9 2.9 1.4 8.8 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Hexokinase_2 PF03727.11 CDJ70272.1 - 1.7e-27 96.1 0.0 1.9e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Hexokinase CAF-1_p150 PF11600.3 CDJ70273.1 - 0.0047 16.3 19.2 0.0047 16.3 13.3 3.2 3 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2052 PF09747.4 CDJ70273.1 - 0.48 10.3 37.0 0.36 10.7 15.0 3.1 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.9 CDJ70273.1 - 0.97 8.9 20.9 1.5 8.3 9.0 2.7 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Mitofilin PF09731.4 CDJ70273.1 - 2.2 6.8 37.5 0.26 9.8 1.6 2.3 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF4557 PF15101.1 CDJ70273.1 - 3.3 7.4 49.4 0.26 11.1 17.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) Dapper PF15268.1 CDJ70275.1 - 1.8 7.2 66.6 2.8 6.6 46.2 1.3 1 0 0 1 1 1 0 Dapper AAA_23 PF13476.1 CDJ70276.1 - 0.017 15.4 5.5 0.032 14.5 3.8 1.4 1 0 0 1 1 1 0 AAA domain Rubredoxin PF00301.15 CDJ70276.1 - 0.028 14.3 0.4 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 Rubredoxin RRM_1 PF00076.17 CDJ70277.1 - 0.027 14.1 0.1 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_A PF00476.15 CDJ70278.1 - 6.1e-53 179.8 0.0 5.8e-40 137.0 0.0 2.7 2 1 0 2 2 2 2 DNA polymerase family A LRRNT PF01462.13 CDJ70278.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Orexin PF02072.10 CDJ70279.1 - 0.017 14.9 1.4 0.017 14.9 0.9 2.1 1 1 1 2 2 2 0 Prepro-orexin MeMO_Hyd_G PF02964.11 CDJ70281.1 - 0.054 13.4 0.2 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain MIP-T3 PF10243.4 CDJ70282.1 - 0.0018 16.8 44.5 0.002 16.7 30.8 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDJ70282.1 - 1.7 6.7 41.3 2.1 6.3 28.6 1.1 1 0 0 1 1 1 0 Utp14 protein HEAT_EZ PF13513.1 CDJ70283.1 - 1e-11 44.9 13.7 5.7e-07 29.8 0.0 11.7 11 2 2 13 13 13 6 HEAT-like repeat HEAT PF02985.17 CDJ70283.1 - 1.7e-09 36.9 21.0 0.11 12.6 0.1 9.0 9 0 0 9 9 9 3 HEAT repeat Arm PF00514.18 CDJ70283.1 - 2.2e-05 24.1 13.7 0.35 10.7 0.6 6.0 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDJ70283.1 - 6.4e-05 23.1 33.8 0.0087 16.3 0.2 7.0 3 3 5 8 8 8 5 HEAT repeats Cnd1 PF12717.2 CDJ70283.1 - 7e-05 22.7 0.8 0.09 12.6 0.0 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CDJ70283.1 - 0.00041 20.6 0.1 0.1 12.9 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF912 PF06024.7 CDJ70283.1 - 0.82 9.7 0.0 0.82 9.7 0.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SpoIIE PF07228.7 CDJ70284.1 - 0.00054 19.7 0.0 0.00054 19.7 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) DUF1127 PF06568.6 CDJ70284.1 - 0.1 12.0 0.6 0.21 11.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) BPD_transp_2 PF02653.11 CDJ70284.1 - 0.15 11.0 3.0 0.12 11.3 1.5 1.3 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Med15 PF09606.5 CDJ70284.1 - 1.1 7.3 7.4 1.3 7.1 5.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PP2C_2 PF13672.1 CDJ70284.1 - 3.9 6.8 12.7 0.72 9.2 0.5 2.7 2 1 0 2 2 2 0 Protein phosphatase 2C ADH_zinc_N PF00107.21 CDJ70285.1 - 2.7e-24 85.1 0.1 5.4e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CDJ70285.1 - 1.1e-15 58.6 0.0 1.9e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_C97 PF05903.9 CDJ70286.1 - 1.6e-16 60.4 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Msg2_C PF12373.3 CDJ70286.1 - 0.077 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Tau95 PF09734.4 CDJ70287.1 - 0.0022 17.3 1.0 0.038 13.3 1.1 2.1 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit FimP PF09766.4 CDJ70287.1 - 0.42 9.6 24.6 0.56 9.2 5.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein eIF-3_zeta PF05091.7 CDJ70287.1 - 1.2 7.6 14.7 2 6.9 1.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Topoisom_I_N PF02919.10 CDJ70287.1 - 1.5 8.1 5.6 5.4 6.2 0.4 2.1 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment zf-DHHC PF01529.15 CDJ70287.1 - 1.7 7.9 4.9 5.5 6.3 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Serinc PF03348.10 CDJ70287.1 - 5.7 5.5 8.3 10 4.7 1.1 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) CytB6-F_Fe-S PF08802.5 CDJ70288.1 - 0.00082 19.3 0.6 0.0011 18.9 0.4 1.1 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit Kinesin PF00225.18 CDJ70289.1 - 0.17 10.5 0.0 0.17 10.5 0.0 1.6 2 0 0 2 2 2 0 Kinesin motor domain UPF0564 PF10595.4 CDJ70291.1 - 0.00014 20.8 1.8 0.00014 20.8 1.2 2.1 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 Suf PF05843.9 CDJ70291.1 - 0.42 10.3 19.8 0.73 9.5 3.3 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDJ70291.1 - 2.9 6.8 29.4 3.4 6.6 6.2 2.2 2 0 0 2 2 2 0 Fms-interacting protein Ndc1_Nup PF09531.5 CDJ70291.1 - 3.4 5.9 10.0 5.1 5.4 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.8 CDJ70291.1 - 3.6 7.6 23.0 1.2 9.2 5.8 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.8 CDJ70292.1 - 0.86 9.4 8.1 1.1 9.1 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HlyD_2 PF12700.2 CDJ70293.1 - 7.5 5.5 16.5 9.4 5.2 11.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein MFS_1 PF07690.11 CDJ70294.1 - 2.8e-07 29.5 9.8 3.4e-07 29.2 6.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4149 PF13664.1 CDJ70295.1 - 0.013 15.5 3.5 0.022 14.8 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Yip1 PF04893.12 CDJ70295.1 - 0.073 12.5 5.2 1.6 8.2 3.5 2.1 1 1 0 1 1 1 0 Yip1 domain Frag1 PF10277.4 CDJ70295.1 - 0.075 12.5 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family UPF0182 PF03699.8 CDJ70295.1 - 0.19 9.6 1.3 0.24 9.2 0.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF418 PF04235.7 CDJ70295.1 - 0.35 10.5 6.6 0.067 12.8 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF418) Nodulin-like PF06813.8 CDJ70295.1 - 0.35 10.0 2.2 0.26 10.4 0.1 1.7 1 1 1 2 2 2 0 Nodulin-like DUF3357 PF11837.3 CDJ70295.1 - 0.6 9.9 3.5 0.47 10.3 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) WHG PF13305.1 CDJ70295.1 - 1.3 9.6 4.3 4 8.0 3.0 2.0 1 1 0 1 1 1 0 WHG domain OmpH PF03938.9 CDJ70295.1 - 3.4 7.5 12.7 29 4.5 8.8 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Glycos_transf_2 PF00535.21 CDJ70296.1 - 2e-18 66.6 0.0 3.1e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CDJ70296.1 - 8.9e-13 48.3 0.1 8.9e-13 48.3 0.1 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CDJ70296.1 - 1.2e-06 27.8 1.2 1.7e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CDJ70296.1 - 4e-06 26.7 0.5 0.00012 21.9 0.4 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CDJ70296.1 - 1.8e-05 24.0 0.0 3.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 GlcNAc PF11397.3 CDJ70296.1 - 0.021 13.9 2.0 0.35 9.9 1.4 2.0 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) CDtoxinA PF03498.9 CDJ70296.1 - 0.12 11.7 0.1 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Cytolethal distending toxin A/C family CAP_GLY PF01302.20 CDJ70298.1 - 6.7e-09 35.3 0.2 3e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 CAP-Gly domain Spt20 PF12090.3 CDJ70298.1 - 0.00065 19.1 2.6 0.16 11.2 0.6 2.2 2 0 0 2 2 2 2 Spt20 family AAA_23 PF13476.1 CDJ70298.1 - 0.0046 17.2 1.2 0.013 15.8 0.8 1.6 1 1 0 1 1 1 1 AAA domain RAB3GAP2_N PF14655.1 CDJ70298.1 - 0.016 14.2 0.8 0.016 14.2 0.5 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Shadoo PF14999.1 CDJ70298.1 - 0.16 11.8 16.8 0.099 12.4 1.2 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF2722 PF10846.3 CDJ70298.1 - 0.18 10.7 0.0 0.18 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Suf PF05843.9 CDJ70298.1 - 5.6 6.5 12.9 4.1 7.0 2.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.14 CDJ70298.1 - 5.6 7.4 32.3 4.3 7.8 5.8 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein 5_3_exonuc_N PF02739.11 CDJ70299.1 - 6.6e-18 64.6 0.0 8.6e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain Med15 PF09606.5 CDJ70300.1 - 2.3e-07 29.4 50.9 3.5e-07 28.8 35.3 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 CDJ70300.1 - 0.45 10.3 5.5 0.78 9.5 3.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PLRV_ORF5 PF01690.12 CDJ70300.1 - 0.55 9.3 12.2 0.75 8.8 8.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Bax1-I PF01027.15 CDJ70300.1 - 0.9 9.1 3.7 1.7 8.1 2.6 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 PAT1 PF09770.4 CDJ70300.1 - 4.4 5.4 49.5 6.2 4.9 34.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PQQ_3 PF13570.1 CDJ70301.1 - 0.00053 20.1 4.2 0.0048 17.1 0.0 3.7 3 1 0 3 3 3 1 PQQ-like domain PQQ_2 PF13360.1 CDJ70301.1 - 0.046 13.1 1.9 5.5 6.3 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain RAB3GAP2_N PF14655.1 CDJ70301.1 - 3.2 6.6 9.2 0.16 10.9 0.6 2.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SR-25 PF10500.4 CDJ70304.1 - 0.0071 15.8 15.0 0.0071 15.8 10.4 5.4 5 1 0 5 5 5 1 Nuclear RNA-splicing-associated protein RabGAP-TBC PF00566.13 CDJ70305.1 - 7.1e-38 130.2 0.9 2.1e-37 128.6 0.7 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3620 PF12281.3 CDJ70305.1 - 0.0096 15.6 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3620) SR-25 PF10500.4 CDJ70305.1 - 0.047 13.1 32.8 0.14 11.6 5.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDJ70305.1 - 0.3 11.1 33.2 0.89 9.6 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF3123 PF11321.3 CDJ70305.1 - 0.5 10.6 3.2 25 5.1 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Dehydrin PF00257.14 CDJ70305.1 - 2.9 8.2 11.4 0.91 9.8 2.3 2.1 2 0 0 2 2 2 0 Dehydrin SoxE PF06525.6 CDJ70305.1 - 3.5 6.8 6.6 16 4.7 0.1 2.2 2 0 0 2 2 2 0 Sulfocyanin (SoxE) DUF1908 PF08926.6 CDJ70305.1 - 3.9 6.1 10.8 0.93 8.1 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) SR-25 PF10500.4 CDJ70306.1 - 0.0002 20.9 16.5 0.00024 20.6 11.5 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDJ70306.1 - 0.084 12.2 16.4 0.093 12.1 11.4 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FCD PF07729.7 CDJ70306.1 - 0.18 12.1 4.9 0.2 12.0 3.4 1.1 1 0 0 1 1 1 0 FCD domain Peptidase_C58 PF03543.9 CDJ70306.1 - 0.23 10.9 12.9 0.22 10.9 8.9 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Nop53 PF07767.6 CDJ70306.1 - 0.3 10.0 14.2 0.31 9.9 9.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FimP PF09766.4 CDJ70306.1 - 0.4 9.7 17.1 0.42 9.6 11.9 1.0 1 0 0 1 1 1 0 Fms-interacting protein Rpp20 PF12328.3 CDJ70306.1 - 0.61 9.7 7.4 0.72 9.4 5.1 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Med15 PF09606.5 CDJ70306.1 - 0.71 7.9 25.0 0.7 8.0 17.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDJ70306.1 - 0.86 7.7 20.7 0.8 7.8 14.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDJ70306.1 - 1.3 7.7 24.4 1.3 7.7 16.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Gemini_AL2 PF01440.11 CDJ70306.1 - 1.4 9.0 15.7 1.7 8.7 10.9 1.1 1 0 0 1 1 1 0 Geminivirus AL2 protein Spt20 PF12090.3 CDJ70306.1 - 1.5 8.1 10.9 1.7 7.9 7.5 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDJ70306.1 - 1.5 8.4 17.2 1.5 8.5 11.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.3 CDJ70306.1 - 1.6 7.9 26.4 2 7.6 18.3 1.1 1 0 0 1 1 1 0 SprA-related family DUF4175 PF13779.1 CDJ70306.1 - 2.2 5.8 22.1 2.2 5.8 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PH_4 PF15404.1 CDJ70306.1 - 3.8 7.0 9.0 4.5 6.7 6.2 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain RR_TM4-6 PF06459.7 CDJ70306.1 - 4.5 7.0 10.3 4.3 7.1 7.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDJ70306.1 - 4.8 6.5 14.6 5 6.5 10.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PsbW PF07123.7 CDJ70306.1 - 6.3 6.8 8.6 7 6.7 6.0 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) G0-G1_switch_2 PF15103.1 CDJ70306.1 - 6.3 7.0 9.2 8.1 6.7 6.3 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 Baculo_PP31 PF05311.6 CDJ70306.1 - 7 5.8 11.6 7.9 5.6 8.1 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF1764 PF08576.5 CDJ70306.1 - 7.7 7.3 11.8 10 6.9 8.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3043 PF11241.3 CDJ70306.1 - 7.8 6.0 8.9 9 5.8 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) OmpH PF03938.9 CDJ70306.1 - 8.3 6.3 23.6 9 6.2 16.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FNIP_N PF14636.1 CDJ70306.1 - 9.1 6.7 16.3 9.5 6.6 11.3 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus NDK PF00334.14 CDJ70307.1 - 1.4e-35 122.0 0.0 1.5e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 CDJ70307.1 - 0.053 13.2 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Caldesmon PF02029.10 CDJ70308.1 - 0.017 13.5 16.9 0.021 13.2 11.7 1.0 1 0 0 1 1 1 0 Caldesmon MtaB PF12176.3 CDJ70308.1 - 0.11 10.8 2.9 0.14 10.5 2.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit YjeF_N PF03853.10 CDJ70308.1 - 0.31 10.6 0.1 0.31 10.6 0.1 2.2 1 1 1 2 2 2 0 YjeF-related protein N-terminus DUF4411 PF14367.1 CDJ70308.1 - 0.57 9.8 8.2 0.88 9.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Lipase_GDSL_3 PF14606.1 CDJ70308.1 - 1.8 8.2 7.7 3.6 7.2 5.3 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Mif2_N PF15624.1 CDJ70308.1 - 3.7 8.1 11.5 5.2 7.6 8.0 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal ABC2_membrane_3 PF12698.2 CDJ70308.1 - 5.3 5.9 4.9 6 5.7 3.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Neur_chan_memb PF02932.11 CDJ70308.1 - 6.4 6.5 8.6 7.9 6.2 5.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Radial_spoke_3 PF06098.6 CDJ70309.1 - 1.8e-39 135.5 5.6 1.8e-39 135.5 3.9 3.2 3 0 0 3 3 3 1 Radial spoke protein 3 TAXi_C PF14541.1 CDJ70309.1 - 2e-17 63.1 0.0 5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 CDJ70309.1 - 1.2e-14 54.2 0.0 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CDJ70309.1 - 3.6e-07 30.2 1.9 3.6e-07 30.2 1.3 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Ribosomal_60s PF00428.14 CDJ70310.1 - 3.5e-05 24.1 9.8 7.1e-05 23.1 6.8 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Med15 PF09606.5 CDJ70312.1 - 0.0018 16.6 139.0 0.014 13.6 9.5 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ70312.1 - 0.012 15.0 2.3 0.012 15.0 1.6 4.6 2 1 0 2 2 2 0 Spt20 family Surface_antigen PF11054.3 CDJ70313.1 - 5.6e-65 219.2 1.8 7.6e-65 218.8 1.2 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ70314.1 - 1.5e-78 263.7 2.6 1.6e-78 263.6 1.8 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ70315.1 - 6.9e-79 264.8 0.5 7.7e-79 264.6 0.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDJ70316.1 - 2.1e-81 273.0 0.1 2.4e-81 272.9 0.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF1446 PF07287.6 CDJ70316.1 - 0.069 11.6 0.1 0.098 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) Med15 PF09606.5 CDJ70317.1 - 0.71 7.9 114.6 0.29 9.3 71.2 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Clathrin PF00637.15 CDJ70321.1 - 1.3e-172 566.2 19.8 2.6e-29 101.6 0.2 7.5 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CDJ70321.1 - 1.3e-25 89.0 0.3 1.5e-24 85.6 0.0 2.8 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.9 CDJ70321.1 - 9e-09 34.6 2.0 0.17 10.6 0.0 4.2 4 0 0 4 4 4 3 Coatomer WD associated region Clathrin_propel PF01394.15 CDJ70321.1 - 1.4e-06 28.1 0.0 0.00043 20.4 0.0 4.1 4 0 0 4 4 4 1 Clathrin propeller repeat TPR_14 PF13428.1 CDJ70321.1 - 0.028 15.0 26.7 4.2 8.2 0.0 10.9 11 2 2 13 13 13 0 Tetratricopeptide repeat TPR_17 PF13431.1 CDJ70321.1 - 0.048 13.8 0.1 6.9 7.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDJ70321.1 - 0.14 12.1 16.5 1.5 8.8 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDJ70321.1 - 0.16 11.6 8.4 21 4.9 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDJ70321.1 - 5.1 6.8 18.3 24 4.6 0.0 7.6 7 2 0 7 7 7 0 TPR repeat Sugar_tr PF00083.19 CDJ70323.1 - 6.9e-82 275.4 27.4 8.5e-82 275.1 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CDJ70323.1 - 2.2e-35 122.0 53.4 1.6e-26 92.8 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Frataxin_Cyay PF01491.11 CDJ70324.1 - 2.4e-18 65.9 0.0 3.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain SRP9-21 PF05486.7 CDJ70325.1 - 2.3e-11 43.2 0.0 8.6e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle 9 kDa protein (SRP9) Sorting_nexin PF03700.8 CDJ70325.1 - 0.091 12.8 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain Patatin PF01734.17 CDJ70327.1 - 6.9e-06 26.1 2.1 6.2e-05 23.0 1.5 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase ThiF PF00899.16 CDJ70328.1 - 0.00054 19.7 0.0 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 ThiF family OTU PF02338.14 CDJ70329.1 - 5.1e-17 62.5 0.0 1.3e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CDJ70329.1 - 0.065 12.5 0.0 3.3 7.0 0.0 2.3 1 1 1 2 2 2 0 Peptidase C65 Otubain Mito_carr PF00153.22 CDJ70332.1 - 1e-60 201.4 0.2 1.3e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_pol_B PF00136.16 CDJ70333.1 - 4.4e-139 464.2 1.1 6.4e-139 463.7 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CDJ70333.1 - 4.1e-75 252.6 0.0 7e-75 251.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CDJ70333.1 - 6.5e-21 74.1 5.4 1.7e-20 72.7 3.7 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta AAA_2 PF07724.9 CDJ70334.1 - 2.6e-24 86.0 0.1 3.2e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CDJ70334.1 - 1.8e-05 24.9 0.0 2.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CDJ70334.1 - 0.0022 17.8 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 CDJ70335.1 - 4.8e-08 33.8 0.0 8.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CDJ70335.1 - 1.7e-07 31.5 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDJ70335.1 - 1.4e-06 28.0 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CDJ70335.1 - 1.5e-06 28.2 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CDJ70335.1 - 4.2e-06 26.8 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CDJ70335.1 - 6.6e-06 26.4 0.0 1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDJ70335.1 - 1.2e-05 25.4 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CDJ70335.1 - 1.3e-05 24.1 0.2 1.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 TIP49 C-terminus MCM PF00493.18 CDJ70335.1 - 7.5e-05 21.6 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CDJ70335.1 - 0.00049 19.3 0.1 0.0076 15.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CDJ70335.1 - 0.00065 18.8 0.1 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CDJ70335.1 - 0.00098 19.0 0.1 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CDJ70335.1 - 0.0014 18.2 0.1 0.093 12.3 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDJ70335.1 - 0.0016 17.4 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CDJ70335.1 - 0.0021 17.5 0.0 0.0053 16.1 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 CDJ70335.1 - 0.003 17.5 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 CDJ70335.1 - 0.0034 16.9 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 CDJ70335.1 - 0.0034 16.8 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain SKI PF01202.17 CDJ70335.1 - 0.0062 16.4 0.0 0.018 14.9 0.0 1.8 2 1 0 2 2 2 1 Shikimate kinase T2SE PF00437.15 CDJ70335.1 - 0.011 14.6 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 CDJ70335.1 - 0.014 15.1 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CDJ70335.1 - 0.016 14.3 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PROCN PF08083.6 CDJ70335.1 - 0.021 13.3 0.3 0.027 12.9 0.2 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain ResIII PF04851.10 CDJ70335.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 CDJ70335.1 - 0.029 14.2 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDJ70335.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IPT PF01745.11 CDJ70335.1 - 0.036 13.2 0.0 0.063 12.4 0.0 1.5 1 1 0 1 1 1 0 Isopentenyl transferase UPF0079 PF02367.12 CDJ70335.1 - 0.038 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 CDJ70335.1 - 0.047 13.1 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CPT PF07931.7 CDJ70335.1 - 0.057 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 CDJ70335.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase PduV-EutP PF10662.4 CDJ70335.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 CDJ70335.1 - 0.12 12.1 0.1 0.49 10.1 0.0 2.0 1 1 1 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 CDJ70335.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLAMP PF14769.1 CDJ70336.1 - 6.5e-17 61.5 0.4 1.2e-16 60.6 0.3 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 MDFI PF15316.1 CDJ70336.1 - 9.9 6.1 8.6 9.6 6.1 3.4 2.2 1 1 1 2 2 2 0 MyoD family inhibitor Pro_isomerase PF00160.16 CDJ70337.1 - 2.8e-34 118.5 0.0 4.2e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PMC2NT PF08066.7 CDJ70339.1 - 0.008 16.4 2.3 0.008 16.4 1.6 3.5 3 1 0 3 3 3 1 PMC2NT (NUC016) domain Maf1 PF09174.5 CDJ70342.1 - 2e-23 83.1 0.0 9.9e-20 71.1 0.0 2.1 2 0 0 2 2 2 2 Maf1 regulator HSP90 PF00183.13 CDJ70343.1 - 5.5e-113 378.1 18.8 5.2e-103 345.2 8.0 4.5 2 1 1 3 3 3 3 Hsp90 protein HATPase_c_3 PF13589.1 CDJ70343.1 - 2.1e-10 40.3 2.1 8.4e-10 38.4 1.5 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CDJ70343.1 - 2.4e-07 30.4 0.0 5.9e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGK PF00162.14 CDJ70344.1 - 1.1e-41 142.6 0.2 1.5e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3138 PF11336.3 CDJ70344.1 - 0.00058 18.1 7.0 0.00058 18.1 4.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3138) GlcNAc PF11397.3 CDJ70344.1 - 0.051 12.6 0.8 0.1 11.7 0.5 1.6 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) RskA PF10099.4 CDJ70344.1 - 0.35 10.5 16.5 0.021 14.5 7.6 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF1266 PF06889.6 CDJ70344.1 - 1.9 8.2 5.8 0.48 10.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1266) bZIP_C PF12498.3 CDJ70344.1 - 4.2 8.6 9.3 17 6.6 5.2 2.4 2 1 0 2 2 2 0 Basic leucine-zipper C terminal DUF4355 PF14265.1 CDJ70344.1 - 6.3 6.7 12.0 15 5.5 8.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) Bestrophin PF01062.16 CDJ70345.1 - 9e-05 21.5 2.4 0.00017 20.6 0.0 2.2 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel E_Pc_C PF06752.7 CDJ70345.1 - 0.0018 17.8 4.6 0.0018 17.8 3.2 6.4 4 3 1 5 5 5 1 Enhancer of Polycomb C-terminus APC_CDC26 PF10471.4 CDJ70345.1 - 0.044 14.5 1.3 0.044 14.5 0.9 6.3 3 2 2 5 5 5 0 Anaphase-promoting complex APC subunit 1 SAPS PF04499.10 CDJ70345.1 - 2.6 6.5 0.0 2.6 6.5 0.0 3.1 1 1 2 3 3 3 0 SIT4 phosphatase-associated protein Glycos_transf_2 PF00535.21 CDJ70346.1 - 6.1e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 SR-25 PF10500.4 CDJ70346.1 - 0.36 10.2 7.0 0.56 9.6 4.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PGM_PMM_III PF02880.11 CDJ70347.1 - 7.1e-25 87.2 0.0 1.5e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 CDJ70347.1 - 1.7e-10 40.5 0.0 3.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CDJ70347.1 - 4.7e-10 39.7 0.0 3.3e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CDJ70347.1 - 0.00016 21.5 0.0 0.00056 19.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Arf PF00025.16 CDJ70348.1 - 6.5e-76 253.4 0.0 7.4e-76 253.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CDJ70348.1 - 1.1e-13 50.8 0.0 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CDJ70348.1 - 3.1e-12 46.1 0.0 3.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CDJ70348.1 - 1.6e-11 43.5 1.5 2.2e-08 33.1 0.3 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CDJ70348.1 - 2.5e-10 39.8 0.0 2.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CDJ70348.1 - 7.7e-09 36.0 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CDJ70348.1 - 4.4e-05 23.4 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CDJ70348.1 - 0.011 14.8 0.1 0.017 14.1 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 CDJ70348.1 - 0.066 13.0 0.1 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 CDJ70348.1 - 0.14 11.6 0.1 0.53 9.6 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain COX2 PF00116.15 CDJ70349.1 - 1.2e-37 128.3 0.0 1.6e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain CS PF04969.11 CDJ70350.1 - 1.5e-09 38.2 0.0 2.2e-08 34.5 0.0 2.5 2 1 0 2 2 2 1 CS domain SR-25 PF10500.4 CDJ70350.1 - 0.0036 16.8 4.4 0.0036 16.8 3.0 3.8 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein DUF2164 PF09932.4 CDJ70350.1 - 0.14 11.9 1.3 0.24 11.2 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) DUF3446 PF11928.3 CDJ70350.1 - 2.7 8.2 41.4 0.87 9.8 1.7 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) CDC37_N PF03234.9 CDJ70350.1 - 7.5 6.8 23.8 0.08 13.2 1.0 3.9 3 1 0 3 3 3 0 Cdc37 N terminal kinase binding Pro_Al_protease PF02983.9 CDJ70350.1 - 9.9 6.2 16.8 0.29 11.1 2.7 2.6 2 0 0 2 2 2 0 Alpha-lytic protease prodomain PIG-L PF02585.12 CDJ70351.1 - 1.1e-20 74.3 1.0 1e-19 71.3 0.0 2.7 2 1 0 2 2 2 1 GlcNAc-PI de-N-acetylase SAPS PF04499.10 CDJ70351.1 - 0.00074 18.2 2.4 0.024 13.2 0.0 2.1 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein DUF4557 PF15101.1 CDJ70351.1 - 0.015 15.1 23.8 0.33 10.7 4.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) SPX PF03105.14 CDJ70351.1 - 0.033 13.9 0.5 0.033 13.9 0.4 2.7 3 0 0 3 3 3 0 SPX domain Neur_chan_memb PF02932.11 CDJ70351.1 - 0.042 13.7 12.1 0.14 11.9 8.4 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleoside_tran PF01733.13 CDJ70351.1 - 0.09 11.9 1.8 0.83 8.7 0.4 2.3 2 0 0 2 2 2 0 Nucleoside transporter Apt1 PF10351.4 CDJ70351.1 - 0.27 10.0 12.4 0.16 10.7 0.6 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ctr PF04145.10 CDJ70351.1 - 0.3 11.1 11.0 3.1 7.8 2.7 3.2 3 0 0 3 3 3 0 Ctr copper transporter family Spore_coat_CotO PF14153.1 CDJ70351.1 - 0.47 9.8 28.0 0.57 9.5 9.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Suf PF05843.9 CDJ70351.1 - 1 9.0 17.8 1.1 8.9 3.2 2.4 3 0 0 3 3 2 0 Suppressor of forked protein (Suf) SpoIIP PF07454.6 CDJ70351.1 - 1.6 7.8 13.5 1.9 7.5 0.3 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Peptidase_S15 PF02129.13 CDJ70351.1 - 2.5 7.4 7.7 3.8 6.8 0.1 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3306 PF11748.3 CDJ70351.1 - 4.1 8.1 27.3 0.56 10.8 4.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Dala_Dala_lig_N PF01820.16 CDJ70351.1 - 4.1 7.7 8.3 11 6.4 0.2 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus ResB PF05140.9 CDJ70351.1 - 5.8 5.3 10.5 0.56 8.6 1.7 2.1 2 0 0 2 2 2 0 ResB-like family DUF2052 PF09747.4 CDJ70351.1 - 7.2 6.4 31.8 3.1 7.6 5.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.3 CDJ70351.1 - 7.6 5.0 13.8 7.5 5.0 0.6 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 BCAS2 PF05700.6 CDJ70353.1 - 4.3e-36 124.4 5.7 6e-36 123.9 4.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MitoNEET_N PF10660.4 CDJ70353.1 - 0.059 13.2 0.5 0.15 11.8 0.3 1.7 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Ribosomal_L16 PF00252.13 CDJ70354.1 - 7.4e-32 109.8 0.1 9.2e-32 109.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Peptidase_M20 PF01546.23 CDJ70356.1 - 4.9e-30 104.4 0.4 4.9e-30 104.4 0.3 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDJ70356.1 - 1.3e-10 41.0 0.0 4.9e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.20 CDJ70357.1 - 7.7e-48 162.9 0.0 4e-47 160.5 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDJ70357.1 - 5.7e-21 74.7 0.0 1.3e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CDJ70357.1 - 0.0057 16.0 1.9 0.0063 15.8 0.0 2.0 2 1 0 2 2 2 1 RIO1 family PAN_3 PF08277.7 CDJ70357.1 - 0.28 10.8 0.0 0.55 9.9 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain Med8 PF10232.4 CDJ70358.1 - 1 8.8 4.9 1.1 8.7 3.4 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 TSP9 PF11493.3 CDJ70358.1 - 1.6 9.3 9.1 6.6 7.3 6.3 2.1 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Rotamase_2 PF13145.1 CDJ70358.1 - 3.4 8.3 15.6 4.5 7.9 10.8 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Herpes_capsid PF06112.6 CDJ70358.1 - 4.7 7.2 8.7 5.5 7.0 6.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PAT1 PF09770.4 CDJ70359.1 - 1.3 7.1 96.0 0.0066 14.7 21.5 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MnhB PF04039.8 CDJ70360.1 - 9.7 6.2 11.6 0.14 12.2 1.2 2.4 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter TPR_16 PF13432.1 CDJ70362.1 - 0.00048 20.7 6.7 0.00048 20.7 4.6 11.4 9 4 2 11 11 11 3 Tetratricopeptide repeat SprA-related PF12118.3 CDJ70362.1 - 0.0014 18.0 19.4 0.0014 18.0 13.4 5.8 3 1 1 4 4 4 1 SprA-related family Spore_coat_CotO PF14153.1 CDJ70362.1 - 0.0038 16.6 6.8 0.0038 16.6 4.7 4.2 3 1 0 3 3 3 1 Spore coat protein CotO ABC_tran_2 PF12848.2 CDJ70363.1 - 0.023 14.5 0.5 0.023 14.5 0.3 4.6 3 1 1 4 4 4 0 ABC transporter CDC45 PF02724.9 CDJ70363.1 - 2.7 5.9 16.7 0.091 10.7 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein CAF1C_H4-bd PF12265.3 CDJ70365.1 - 2.6e-18 65.6 0.2 1.4e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CDJ70365.1 - 1.3e-06 28.0 1.8 0.014 15.2 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Med15 PF09606.5 CDJ70365.1 - 0.23 9.6 29.3 0.0058 14.9 11.8 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PLRV_ORF5 PF01690.12 CDJ70365.1 - 5.3 6.0 14.4 1.3 8.0 6.2 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein ACC_epsilon PF13822.1 CDJ70365.1 - 5.4 7.4 6.3 26 5.2 0.2 2.9 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Alkyl_sulf_dimr PF14863.1 CDJ70366.1 - 1.7e-28 99.6 4.0 1.7e-28 99.6 2.8 4.1 4 1 1 5 5 5 1 Alkyl sulfatase dimerisation SPX PF03105.14 CDJ70366.1 - 3.3e-07 30.3 8.9 0.81 9.4 11.2 3.4 3 1 0 3 3 3 2 SPX domain Alkyl_sulf_C PF14864.1 CDJ70366.1 - 7.3e-05 22.7 0.5 0.64 10.0 0.0 3.6 3 0 0 3 3 3 2 Alkyl sulfatase C-terminal SAGA-Tad1 PF12767.2 CDJ70366.1 - 0.00053 19.7 39.9 0.031 13.9 1.6 4.0 4 0 0 4 4 4 3 Transcriptional regulator of RNA polII, SAGA, subunit Lactamase_B PF00753.22 CDJ70366.1 - 0.0012 18.5 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Pex14_N PF04695.8 CDJ70366.1 - 0.0046 17.0 4.1 0.0046 17.0 2.8 5.9 5 1 1 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2721 PF11026.3 CDJ70366.1 - 0.0058 16.2 0.3 0.0058 16.2 0.2 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2721) LMBR1 PF04791.11 CDJ70366.1 - 0.8 8.2 3.3 2.8 6.4 0.1 2.6 3 0 0 3 3 3 0 LMBR1-like membrane protein SAPS PF04499.10 CDJ70366.1 - 1.3 7.6 18.7 3.3 6.2 8.8 2.9 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 CDJ70366.1 - 3.3 5.6 26.3 0.01 13.9 6.7 3.1 4 0 0 4 4 4 0 CDC45-like protein Asp_protease_2 PF13650.1 CDJ70368.1 - 4.3e-09 36.7 0.0 6.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDJ70368.1 - 9.5e-06 25.3 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDJ70368.1 - 0.00025 20.9 0.0 0.0014 18.5 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDJ70368.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Radial_spoke_3 PF06098.6 CDJ70370.1 - 0.23 10.4 5.0 0.26 10.2 3.5 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 YihI PF04220.7 CDJ70370.1 - 0.35 10.1 11.2 0.41 9.9 7.8 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Pex14_N PF04695.8 CDJ70370.1 - 3 7.8 7.4 3.5 7.6 5.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FCP1_C PF09309.5 CDJ70370.1 - 3 7.0 11.3 1.7 7.8 7.0 1.3 1 1 0 1 1 1 0 FCP1, C-terminal NARP1 PF12569.3 CDJ70370.1 - 4.5 5.9 6.1 4.8 5.8 4.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Suf PF05843.9 CDJ70370.1 - 5.2 6.6 9.6 5.7 6.5 6.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDJ70370.1 - 9.4 5.5 7.7 10 5.4 5.3 1.1 1 0 0 1 1 1 0 Spt20 family Dymeclin PF09742.4 CDJ70371.1 - 9.5e-12 43.8 0.0 9.5e-12 43.8 0.0 4.3 3 3 2 5 5 5 1 Dyggve-Melchior-Clausen syndrome protein Porin_4 PF13609.1 CDJ70373.1 - 0.024 14.1 1.5 0.025 14.1 1.1 1.2 1 0 0 1 1 1 0 Gram-negative porin Ashwin PF15323.1 CDJ70374.1 - 0.026 14.5 5.2 0.032 14.2 3.6 1.2 1 0 0 1 1 1 0 Developmental protein Gemini_BL1 PF00845.14 CDJ70374.1 - 0.03 13.6 3.6 0.038 13.3 2.4 1.3 1 1 0 1 1 1 0 Geminivirus BL1 movement protein Neur_chan_memb PF02932.11 CDJ70374.1 - 3.7 7.3 6.9 4.4 7.1 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1675 PF07897.6 CDJ70374.1 - 8.9 6.0 11.6 14 5.4 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) zf-C4H2 PF10146.4 CDJ70377.1 - 0.81 9.6 4.4 2.5 8.0 3.0 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein GSK-3_bind PF05350.7 CDJ70377.1 - 6 6.2 10.9 7.1 6.0 7.6 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding SR-25 PF10500.4 CDJ70378.1 - 0.0072 15.8 3.3 0.0072 15.8 2.3 3.9 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein ETRAMP PF09716.5 CDJ70378.1 - 0.22 11.5 4.1 0.94 9.4 0.1 3.2 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Plasmodium_Vir PF05795.6 CDJ70378.1 - 0.71 9.0 5.3 5.6 6.0 2.9 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein HAUS-augmin3 PF14932.1 CDJ70378.1 - 1.1 8.3 16.4 0.28 10.3 7.1 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Cwf_Cwc_15 PF04889.7 CDJ70378.1 - 2.7 7.6 9.2 9.2 5.8 0.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MRI PF15325.1 CDJ70378.1 - 8.2 7.4 14.8 16 6.5 0.7 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection PIH1 PF08190.7 CDJ70379.1 - 6.1e-06 25.9 18.8 0.00033 20.1 10.8 5.9 2 2 5 7 7 7 2 pre-RNA processing PIH1/Nop17 FimP PF09766.4 CDJ70379.1 - 0.029 13.4 32.7 0.36 9.8 12.0 3.3 3 0 0 3 3 3 0 Fms-interacting protein DUF3959 PF13105.1 CDJ70379.1 - 3 7.0 11.5 12 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Spt20 PF12090.3 CDJ70379.1 - 6.5 6.0 25.2 0.023 14.0 2.3 3.6 4 0 0 4 4 4 0 Spt20 family Methyltransf_23 PF13489.1 CDJ70380.1 - 0.039 13.6 5.0 0.41 10.3 0.3 2.3 1 1 1 2 2 2 0 Methyltransferase domain YjgP_YjgQ PF03739.9 CDJ70380.1 - 0.11 11.1 0.2 0.21 10.2 0.2 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Zn_peptidase PF04228.8 CDJ70380.1 - 0.28 10.3 14.5 0.019 14.2 4.3 2.4 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase zf-DHHC PF01529.15 CDJ70380.1 - 0.34 10.2 3.0 6.6 6.0 0.1 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase DRY_EERY PF09750.4 CDJ70380.1 - 0.53 10.4 8.6 0.46 10.5 2.1 2.6 2 0 0 2 2 2 0 Alternative splicing regulator RR_TM4-6 PF06459.7 CDJ70380.1 - 0.92 9.3 12.4 0.46 10.3 3.8 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Corona_nucleoca PF00937.13 CDJ70380.1 - 1.2 8.0 23.7 0.29 10.0 11.3 2.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein FAM177 PF14774.1 CDJ70380.1 - 1.5 8.7 9.8 0.052 13.4 0.9 2.4 2 0 0 2 2 2 0 FAM177 family eIF_4EBP PF05456.6 CDJ70380.1 - 1.6 8.4 9.9 5.9 6.6 1.7 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF3801 PF12687.2 CDJ70380.1 - 2.1 7.9 12.0 0.78 9.2 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) FimP PF09766.4 CDJ70380.1 - 4.7 6.1 25.2 0.14 11.1 4.0 2.6 3 0 0 3 3 3 0 Fms-interacting protein EIIBC-GUT_N PF03612.9 CDJ70380.1 - 5.5 6.5 6.4 34 3.9 2.0 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus 2-Hacid_dh PF00389.25 CDJ70381.1 - 3.9e-28 97.5 0.3 5.3e-28 97.1 0.2 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.14 CDJ70381.1 - 3.4e-24 84.9 8.3 1.9e-15 56.4 0.0 3.1 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_trans_4_4 PF13579.1 CDJ70381.1 - 0.048 13.8 0.1 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain TSA PF03249.8 CDJ70381.1 - 4.1 5.8 12.1 6.2 5.2 8.4 1.3 1 0 0 1 1 1 0 Type specific antigen APC_CDC26 PF10471.4 CDJ70382.1 - 0.019 15.6 3.0 0.019 15.6 2.1 3.4 3 1 0 3 3 2 0 Anaphase-promoting complex APC subunit 1 Kinocilin PF15033.1 CDJ70382.1 - 0.027 13.9 0.5 0.041 13.4 0.4 1.2 1 0 0 1 1 1 0 Kinocilin protein Dehydrin PF00257.14 CDJ70382.1 - 0.11 12.8 14.2 0.35 11.1 2.9 2.3 2 0 0 2 2 2 0 Dehydrin RskA PF10099.4 CDJ70382.1 - 0.21 11.2 15.1 0.12 12.0 3.9 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Hid1 PF12722.2 CDJ70382.1 - 0.23 9.1 9.1 0.24 9.0 6.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDJ70382.1 - 0.38 8.9 27.7 0.48 8.6 19.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CDJ70382.1 - 0.42 9.9 22.2 0.53 9.6 15.4 1.1 1 0 0 1 1 1 0 Vta1 like Cnd1_N PF12922.2 CDJ70382.1 - 0.56 9.8 0.0 0.56 9.8 0.0 2.9 1 1 1 2 2 1 0 non-SMC mitotic condensation complex subunit 1, N-term SR-25 PF10500.4 CDJ70382.1 - 0.75 9.2 29.1 0.41 10.0 18.8 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PsaN PF05479.6 CDJ70382.1 - 0.83 9.6 5.4 0.11 12.5 0.9 1.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Spc7_N PF15402.1 CDJ70382.1 - 1 7.2 21.0 1.3 6.9 14.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF3464 PF11947.3 CDJ70382.1 - 2 7.8 10.0 0.34 10.3 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) FLO_LFY PF01698.11 CDJ70382.1 - 2.4 6.9 7.8 3.2 6.5 5.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Cid2 PF09774.4 CDJ70382.1 - 2.6 8.1 12.7 0.64 10.1 5.9 1.9 2 0 0 2 2 2 0 Caffeine-induced death protein 2 Apt1 PF10351.4 CDJ70382.1 - 7 5.3 12.8 8.8 5.0 8.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3801 PF12687.2 CDJ70382.1 - 7.4 6.0 13.9 20 4.7 9.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) AvrE PF11725.3 CDJ70382.1 - 9 3.1 18.1 9.7 3.0 12.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor Glutaredoxin PF00462.19 CDJ70383.1 - 3e-06 27.1 0.1 0.0062 16.4 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Med15 PF09606.5 CDJ70383.1 - 0.00074 17.8 91.7 0.019 13.2 20.8 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ70383.1 - 0.003 17.5 54.5 0.033 14.0 17.0 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.1 CDJ70383.1 - 0.0037 16.7 36.3 0.064 12.6 12.6 2.1 2 0 0 2 2 2 2 Spore coat protein CotO SAGA-Tad1 PF12767.2 CDJ70383.1 - 0.0097 15.5 29.1 0.14 11.8 11.7 2.2 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Utp11 PF03998.8 CDJ70383.1 - 0.045 13.5 34.1 0.037 13.8 11.7 2.1 2 0 0 2 2 2 0 Utp11 protein DUF4011 PF13195.1 CDJ70383.1 - 0.19 11.7 23.9 0.067 13.2 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Neur_chan_memb PF02932.11 CDJ70383.1 - 0.38 10.6 18.8 0.32 10.8 5.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 CDJ70383.1 - 0.59 9.8 36.2 0.34 10.6 4.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Band_3_cyto PF07565.8 CDJ70383.1 - 0.68 9.3 25.1 0.95 8.9 6.4 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain GAGA_bind PF06217.7 CDJ70383.1 - 0.95 9.3 22.9 2.1 8.2 2.4 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family AUX_IAA PF02309.11 CDJ70383.1 - 0.97 9.1 24.8 1.2 8.8 7.5 2.2 2 0 0 2 2 2 0 AUX/IAA family SOBP PF15279.1 CDJ70383.1 - 1 9.6 27.9 2.9 8.1 10.1 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Raftlin PF15250.1 CDJ70383.1 - 1 7.8 27.6 0.86 8.0 3.4 2.1 2 0 0 2 2 2 0 Raftlin Tyrosinase PF00264.15 CDJ70383.1 - 1.3 9.1 10.5 3.5 7.7 2.9 2.2 2 0 0 2 2 2 0 Common central domain of tyrosinase Nha1_C PF08619.5 CDJ70383.1 - 1.3 8.1 29.8 2.5 7.2 4.8 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus eIF-3_zeta PF05091.7 CDJ70383.1 - 1.8 7.1 38.2 1.7 7.2 15.2 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF966 PF06136.8 CDJ70383.1 - 1.9 7.8 26.0 3.4 7.0 4.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DUF1510 PF07423.6 CDJ70383.1 - 2 7.7 35.3 1.4 8.2 11.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 CDJ70383.1 - 2.5 6.6 17.3 2.9 6.3 4.4 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Dehydrin PF00257.14 CDJ70383.1 - 4.3 7.6 40.2 0.11 12.8 2.0 3.1 2 1 0 2 2 2 0 Dehydrin AAA_11 PF13086.1 CDJ70383.1 - 4.6 6.7 25.0 1.5 8.3 2.3 2.3 2 0 0 2 2 2 0 AAA domain DUF2052 PF09747.4 CDJ70383.1 - 6.1 6.7 40.7 2.3 8.0 7.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.8 CDJ70383.1 - 7.3 4.9 27.9 4.4 5.7 4.5 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM222A PF15258.1 CDJ70383.1 - 8.2 5.5 50.8 1 8.5 12.6 2.1 2 0 0 2 2 2 0 Protein family of FAM222A Plasmodium_Vir PF05795.6 CDJ70383.1 - 8.4 5.4 14.6 5.3 6.1 1.3 2.3 2 1 0 2 2 2 0 Plasmodium vivax Vir protein Vfa1 PF08432.5 CDJ70383.1 - 9.3 6.2 33.8 6.9 6.6 10.4 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Apt1 PF10351.4 CDJ70384.1 - 0.48 9.2 2.0 0.65 8.7 1.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM117 PF15388.1 CDJ70384.1 - 1 8.5 21.5 1.9 7.6 5.6 2.3 2 1 0 2 2 2 0 Protein Family FAM117 SR-25 PF10500.4 CDJ70384.1 - 1.2 8.5 36.7 2.3 7.6 6.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.8 CDJ70384.1 - 5.1 7.5 14.8 8.1 6.9 4.4 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain DNA_ligase_A_N PF04675.9 CDJ70385.1 - 1.2e-26 93.6 0.0 3.3e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 CDJ70385.1 - 4.6e-06 26.1 0.0 4.6e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 ATP dependent DNA ligase domain AAA_23 PF13476.1 CDJ70385.1 - 2.3 8.4 20.9 7.1 6.8 14.5 1.8 1 0 0 1 1 1 0 AAA domain Plasmodium_Vir PF05795.6 CDJ70387.1 - 0.19 10.9 1.9 0.36 9.9 1.4 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Thioredoxin_2 PF13098.1 CDJ70387.1 - 0.45 10.7 6.4 0.083 13.0 0.8 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain DUF1840 PF08895.6 CDJ70387.1 - 6.7 6.7 17.5 4.2 7.4 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) EamA PF00892.15 CDJ70388.1 - 7.1e-09 35.7 14.3 7.1e-09 35.7 9.9 2.5 2 0 0 2 2 2 1 EamA-like transporter family Peptidase_S64 PF08192.6 CDJ70388.1 - 4.8 5.3 5.6 6.4 4.9 3.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 ODV-E18 PF10717.4 CDJ70388.1 - 6.9 6.1 9.0 1.5 8.3 0.0 3.4 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 P12 PF12669.2 CDJ70388.1 - 7.1 6.9 7.5 2.6 8.2 0.3 3.2 2 1 0 2 2 2 0 Virus attachment protein p12 family ABC2_membrane PF01061.19 CDJ70390.1 - 1.5e-33 115.7 22.7 2e-33 115.3 15.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CDJ70390.1 - 2.4e-23 82.9 0.0 7e-23 81.4 0.0 1.8 1 1 1 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.2 CDJ70390.1 - 1.7e-08 33.9 15.2 6.9e-08 31.8 9.5 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CDJ70390.1 - 2.2e-05 24.5 0.3 0.0014 18.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDJ70390.1 - 0.00023 20.3 0.0 0.00042 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 CDJ70390.1 - 0.0014 17.5 11.6 0.0022 16.9 8.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 CDJ70390.1 - 0.0016 17.9 0.0 0.0062 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDJ70390.1 - 0.0023 17.4 0.1 0.0054 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CDJ70390.1 - 0.024 14.6 0.2 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 CDJ70390.1 - 0.036 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 CDJ70390.1 - 0.081 12.9 0.1 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 CDJ70390.1 - 0.081 13.2 0.1 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain BMC PF00936.14 CDJ70391.1 - 0.0081 15.8 1.1 0.011 15.3 0.8 1.2 1 0 0 1 1 1 1 BMC domain SURF1 PF02104.10 CDJ70392.1 - 1.1e-28 100.6 0.5 3e-25 89.3 0.3 3.1 1 1 0 1 1 1 1 SURF1 family WW PF00397.21 CDJ70393.1 - 4.8e-07 29.5 1.9 1.2e-06 28.3 1.3 1.7 1 0 0 1 1 1 1 WW domain PSP1 PF04468.7 CDJ70393.1 - 0.28 11.2 0.0 0.28 11.2 0.0 2.6 3 0 0 3 3 3 0 PSP1 C-terminal conserved region Prok-RING_1 PF14446.1 CDJ70393.1 - 3.8 7.3 8.1 4.1 7.2 0.5 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DegT_DnrJ_EryC1 PF01041.12 CDJ70395.1 - 1e-17 64.2 0.0 1.6e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Dynein_heavy PF03028.10 CDJ70396.1 - 4.8e-157 524.0 0.0 5.4e-157 523.8 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 CDJ70397.1 - 3.6e-12 45.6 0.7 5.2e-12 45.1 0.5 1.2 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 THOC7 PF05615.8 CDJ70397.1 - 0.063 13.5 0.5 0.063 13.5 0.3 1.6 2 0 0 2 2 2 0 Tho complex subunit 7 WASH_WAHD PF11945.3 CDJ70397.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex MT PF12777.2 CDJ70398.1 - 2.2e-44 151.6 5.8 3e-44 151.2 4.0 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CDJ70398.1 - 8.1e-16 57.5 0.0 1.5e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDJ70398.1 - 9.1e-07 28.1 0.0 1.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 IncA PF04156.9 CDJ70398.1 - 0.0031 17.1 3.2 0.0031 17.1 2.2 2.6 2 0 0 2 2 2 1 IncA protein Laminin_I PF06008.9 CDJ70398.1 - 0.0096 15.2 4.3 0.0096 15.2 3.0 2.5 2 1 1 3 3 3 1 Laminin Domain I TelA PF05816.6 CDJ70398.1 - 0.17 10.5 10.6 0.53 8.9 1.5 2.3 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) KxDL PF10241.4 CDJ70398.1 - 0.2 11.6 2.3 0.44 10.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.7 CDJ70398.1 - 0.23 11.2 9.6 0.46 10.2 0.6 2.8 2 1 0 2 2 2 0 Laminin Domain II DUF4140 PF13600.1 CDJ70398.1 - 0.38 11.2 13.1 13 6.2 0.2 4.4 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.6 CDJ70398.1 - 0.57 8.7 12.1 0.024 13.3 1.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 CDJ70398.1 - 0.81 9.8 6.4 0.65 10.1 1.0 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0449 PF15136.1 CDJ70398.1 - 1.4 9.2 11.8 1.3 9.2 0.4 3.9 3 2 1 4 4 4 0 Uncharacterised protein family UPF0449 DUF948 PF06103.6 CDJ70398.1 - 1.7 8.5 4.5 1.1 9.1 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 CDJ70398.1 - 1.8 7.4 11.0 0.56 9.0 1.4 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 CDJ70398.1 - 2 8.2 9.4 6.1 6.6 1.4 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) APG6 PF04111.7 CDJ70398.1 - 2.1 7.3 13.9 1.1 8.1 1.7 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 CDJ70398.1 - 2.8 8.0 10.1 0.65 10.1 2.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 CDJ70398.1 - 4.2 7.6 7.1 2.4 8.4 1.0 2.3 2 0 0 2 2 2 0 AAA domain FemAB PF02388.11 CDJ70398.1 - 4.7 5.7 8.3 5.5 5.5 0.9 2.1 2 0 0 2 2 2 0 FemAB family DivIVA PF05103.8 CDJ70398.1 - 4.8 7.2 17.0 1.8 8.6 3.0 3.2 2 1 1 3 3 3 0 DivIVA protein Mnd1 PF03962.10 CDJ70398.1 - 5 6.7 13.1 0.23 11.1 1.8 2.4 2 0 0 2 2 2 0 Mnd1 family Syntaxin-6_N PF09177.6 CDJ70398.1 - 7.4 7.0 10.4 6.1 7.3 1.1 4.0 4 0 0 4 4 4 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 CDJ70398.1 - 7.8 6.2 20.5 5.1 6.8 4.1 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 CDJ70398.1 - 8.3 6.3 15.1 4 7.3 1.9 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_7 PF12775.2 CDJ70399.1 - 8.4e-29 100.4 0.0 1.1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDJ70399.1 - 0.00061 19.5 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CDJ70399.1 - 0.0018 17.0 0.1 0.015 14.0 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus Imm28 PF15574.1 CDJ70399.1 - 0.012 15.1 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 28 AAA PF00004.24 CDJ70399.1 - 0.014 15.5 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDJ70399.1 - 0.025 14.5 0.2 0.058 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 CDJ70399.1 - 0.069 12.6 0.1 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CDJ70399.1 - 0.081 12.0 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CDJ70399.1 - 0.082 12.6 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CDJ70399.1 - 0.085 13.0 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 CDJ70399.1 - 0.11 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CDJ70399.1 - 0.13 11.8 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CDJ70399.1 - 0.16 10.8 0.6 3.2 6.5 0.1 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_6 PF12774.2 CDJ70400.1 - 1e-18 67.7 0.1 3.8e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CDJ70400.1 - 2.9e-09 36.7 0.1 5.4e-07 29.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CDJ70400.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDJ70400.1 - 0.0034 16.8 0.1 0.032 13.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CDJ70400.1 - 0.0068 16.4 0.3 0.023 14.6 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 CDJ70400.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 CDJ70400.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CDJ70400.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 CDJ70400.1 - 0.025 13.7 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CDJ70400.1 - 0.027 15.2 0.1 0.073 13.8 0.1 1.8 2 1 0 2 2 1 0 AAA domain Rad17 PF03215.10 CDJ70400.1 - 0.031 12.9 0.1 0.5 8.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 CDJ70400.1 - 0.049 13.4 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDJ70400.1 - 0.053 13.2 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 CDJ70400.1 - 0.066 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CDJ70400.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CDJ70400.1 - 0.083 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CDJ70400.1 - 0.12 11.9 0.1 0.92 9.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DHC_N2 PF08393.8 CDJ70401.1 - 4e-60 203.4 6.0 1.2e-54 185.4 0.5 2.4 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDJ70401.1 - 1.2e-13 51.1 0.2 2.1e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Flagellin_C PF00700.16 CDJ70401.1 - 0.039 14.1 0.4 0.35 11.0 0.1 2.4 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DHC_N2 PF08393.8 CDJ70402.1 - 8.7e-15 54.1 0.2 8.7e-15 54.1 0.2 2.8 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DegS PF05384.6 CDJ70402.1 - 0.0041 16.3 3.2 0.02 14.0 1.4 2.6 2 0 0 2 2 2 1 Sensor protein DegS Transposase_22 PF02994.9 CDJ70403.1 - 0.3 9.5 10.3 0.45 8.9 7.1 1.2 1 0 0 1 1 1 0 L1 transposable element TcdA_TcdB PF12919.2 CDJ70403.1 - 0.32 9.4 6.7 0.49 8.8 4.6 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain ArgK PF03308.11 CDJ70403.1 - 0.63 8.7 4.6 0.91 8.2 3.2 1.2 1 0 0 1 1 1 0 ArgK protein OmpH PF03938.9 CDJ70403.1 - 3.2 7.6 19.4 6.2 6.7 13.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Retrotrans_gag PF03732.12 CDJ70403.1 - 7.4 6.7 13.5 30 4.7 8.9 2.4 2 1 0 2 2 2 0 Retrotransposon gag protein UCH PF00443.24 CDJ70404.1 - 4.4e-47 160.4 0.0 8.9e-47 159.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDJ70404.1 - 1.1e-14 54.6 0.6 4.4e-08 32.9 0.0 2.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CDJ70404.1 - 1.1e-11 44.6 0.0 5.5e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CDJ70404.1 - 1.1e-07 31.5 0.6 0.00058 19.6 0.0 3.2 3 0 0 3 3 3 2 UBA/TS-N domain RuvA_C PF07499.8 CDJ70404.1 - 0.003 17.6 4.8 0.39 10.9 0.1 3.1 3 0 0 3 3 3 2 RuvA, C-terminal domain ArfGap PF01412.13 CDJ70404.1 - 0.43 10.3 3.2 0.3 10.8 0.2 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf SRP14 PF02290.10 CDJ70405.1 - 3.6e-16 58.8 1.1 1.1e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle 14kD protein FimP PF09766.4 CDJ70405.1 - 0.046 12.7 10.3 0.059 12.4 7.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4387 PF14330.1 CDJ70405.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4387) rve PF00665.21 CDJ70406.1 - 1.4e-14 54.2 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDJ70406.1 - 5e-05 22.8 0.0 9.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SDA1 PF05285.7 CDJ70407.1 - 0.00057 19.2 34.6 0.00069 18.9 24.0 1.2 1 0 0 1 1 1 1 SDA1 YL1 PF05764.8 CDJ70407.1 - 0.0034 17.0 33.3 0.0045 16.6 23.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF2890 PF11081.3 CDJ70407.1 - 0.0072 16.4 22.1 0.0091 16.0 15.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Daxx PF03344.10 CDJ70407.1 - 0.012 14.2 35.9 0.013 14.0 24.9 1.1 1 0 0 1 1 1 0 Daxx Family Nop53 PF07767.6 CDJ70407.1 - 0.013 14.4 34.2 0.018 14.0 23.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Utp14 PF04615.8 CDJ70407.1 - 0.027 12.6 30.7 0.029 12.5 21.3 1.0 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 CDJ70407.1 - 0.038 12.0 35.9 0.05 11.6 24.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Ebola_NP PF05505.7 CDJ70407.1 - 0.052 11.6 23.4 0.061 11.3 16.2 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein CENP-T PF15511.1 CDJ70407.1 - 0.052 12.7 26.2 0.055 12.7 18.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Lin-8 PF03353.10 CDJ70407.1 - 0.069 12.4 18.7 0.077 12.2 12.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GAGA_bind PF06217.7 CDJ70407.1 - 0.25 11.2 13.2 0.33 10.8 9.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Suf PF05843.9 CDJ70407.1 - 0.36 10.5 11.8 0.39 10.4 8.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.7 CDJ70407.1 - 0.57 8.0 47.8 0.67 7.7 33.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 CDJ70407.1 - 0.76 9.1 23.0 0.85 8.9 16.0 1.0 1 0 0 1 1 1 0 Vta1 like DUF572 PF04502.8 CDJ70407.1 - 1.2 8.2 24.3 1.4 8.0 16.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Paf1 PF03985.8 CDJ70407.1 - 2.3 6.8 34.6 3.3 6.3 24.0 1.4 1 0 0 1 1 1 0 Paf1 BUD22 PF09073.5 CDJ70407.1 - 2.6 7.0 42.9 3.3 6.6 29.7 1.1 1 0 0 1 1 1 0 BUD22 Glypican PF01153.14 CDJ70407.1 - 2.8 6.4 15.1 3.4 6.1 10.4 1.1 1 0 0 1 1 1 0 Glypican PLRV_ORF5 PF01690.12 CDJ70407.1 - 2.9 6.9 19.4 3.3 6.7 13.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Herpes_DNAp_acc PF04929.7 CDJ70407.1 - 4.1 6.2 20.6 5.3 5.9 14.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DARPP-32 PF05395.7 CDJ70407.1 - 4.9 7.2 26.6 7.1 6.7 18.4 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Neur_chan_memb PF02932.11 CDJ70407.1 - 5.8 6.7 8.3 6.7 6.5 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S64 PF08192.6 CDJ70407.1 - 7.7 4.7 10.8 8.7 4.5 7.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 Raftlin PF15250.1 CDJ70407.1 - 8.1 4.8 15.0 10 4.4 10.4 1.3 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.2 CDJ70407.1 - 8.4 3.9 19.0 9.2 3.7 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CLAG PF03805.8 CDJ70408.1 - 0.06 10.6 0.0 0.49 7.6 0.0 1.9 2 0 0 2 2 2 0 Cytoadherence-linked asexual protein FimP PF09766.4 CDJ70409.1 - 0.0016 17.5 13.6 0.0016 17.5 9.5 2.3 2 0 0 2 2 2 1 Fms-interacting protein SAPS PF04499.10 CDJ70409.1 - 0.0021 16.7 18.7 0.0028 16.3 12.9 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF3007 PF11460.3 CDJ70409.1 - 0.0072 16.3 2.6 0.0072 16.3 1.8 2.3 2 0 0 2 2 1 1 Protein of unknown function (DUF3007) YqfQ PF14181.1 CDJ70409.1 - 0.013 15.5 12.2 0.013 15.5 8.4 2.1 2 0 0 2 2 2 0 YqfQ-like protein Pex14_N PF04695.8 CDJ70409.1 - 0.028 14.4 45.7 0.017 15.1 13.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_Ag35 PF03286.9 CDJ70409.1 - 0.055 12.9 15.8 0.47 9.9 0.2 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Neur_chan_memb PF02932.11 CDJ70409.1 - 0.061 13.2 18.8 0.093 12.5 13.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 CDJ70409.1 - 0.064 12.6 41.7 0.058 12.8 13.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Eapp_C PF10238.4 CDJ70409.1 - 0.24 11.2 22.5 0.22 11.3 3.4 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Ctr PF04145.10 CDJ70409.1 - 0.26 11.3 18.7 1 9.3 1.5 2.3 2 0 0 2 2 2 0 Ctr copper transporter family FLO_LFY PF01698.11 CDJ70409.1 - 0.32 9.8 28.9 0.3 9.9 2.5 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein Bul1_N PF04425.7 CDJ70409.1 - 0.34 9.4 26.9 0.06 11.8 7.3 2.0 2 0 0 2 2 2 0 Bul1 N terminus FYDLN_acid PF09538.5 CDJ70409.1 - 0.38 11.3 15.4 0.75 10.4 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Kei1 PF08552.6 CDJ70409.1 - 0.44 10.1 21.5 0.83 9.2 5.4 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4045 PF13254.1 CDJ70409.1 - 0.5 9.5 22.1 0.11 11.8 5.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) BORG_CEP PF14957.1 CDJ70409.1 - 0.6 11.0 21.3 1.2 10.0 1.7 2.1 2 0 0 2 2 2 0 Cdc42 effector DDHD PF02862.12 CDJ70409.1 - 0.82 9.4 28.6 0.46 10.2 2.7 2.0 2 0 0 2 2 2 0 DDHD domain Peptidase_S49_N PF08496.5 CDJ70409.1 - 0.93 9.2 31.6 0.28 10.9 8.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal GCD14 PF08704.5 CDJ70409.1 - 1.1 8.6 14.8 1.7 8.0 1.7 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF4366 PF14283.1 CDJ70409.1 - 1.2 8.5 13.3 2.3 7.5 3.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) HNOBA PF07701.9 CDJ70409.1 - 1.4 8.0 21.2 0.17 11.1 3.4 2.2 2 0 0 2 2 2 0 Heme NO binding associated DUF2072 PF09845.4 CDJ70409.1 - 1.5 8.7 16.7 1.9 8.4 4.2 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) FHIPEP PF00771.15 CDJ70409.1 - 1.6 6.9 20.5 0.49 8.6 2.3 2.0 2 0 0 2 2 2 0 FHIPEP family TFIIF_beta PF02270.10 CDJ70409.1 - 1.7 8.4 32.9 0.85 9.3 9.2 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, beta subunit LIM_bind PF01803.11 CDJ70409.1 - 2 7.4 43.5 0.11 11.5 14.1 2.0 2 0 0 2 2 2 0 LIM-domain binding protein RNA_pol_Rpc4 PF05132.9 CDJ70409.1 - 2.3 8.2 29.6 1.6 8.6 9.3 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM60A PF15396.1 CDJ70409.1 - 2.4 7.8 24.5 1.4 8.6 7.2 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Band_3_cyto PF07565.8 CDJ70409.1 - 2.6 7.5 35.4 1.1 8.7 4.9 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain SpoIIP PF07454.6 CDJ70409.1 - 2.6 7.1 25.0 0.73 8.9 6.8 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4011 PF13195.1 CDJ70409.1 - 3 7.8 18.3 1.5 8.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Inhibitor_I71 PF12628.2 CDJ70409.1 - 3.8 7.1 19.8 0.51 9.9 3.7 2.1 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor TFIIA PF03153.8 CDJ70409.1 - 3.9 7.2 60.8 0.66 9.8 21.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.1 CDJ70409.1 - 4 7.6 28.7 0.51 10.5 2.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Stig1 PF04885.8 CDJ70409.1 - 5.5 7.2 17.2 2.1 8.5 3.2 2.2 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 Senescence_reg PF04520.8 CDJ70409.1 - 6.4 7.2 17.5 4.1 7.8 5.0 2.2 2 0 0 2 2 2 0 Senescence regulator DUF702 PF05142.7 CDJ70409.1 - 6.8 6.8 30.4 0.9 9.7 7.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) AIF_C PF14721.1 CDJ70409.1 - 7.4 6.8 30.5 3.1 8.0 4.6 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2052 PF09747.4 CDJ70409.1 - 7.7 6.4 39.8 2.2 8.1 13.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Pal1 PF08316.6 CDJ70409.1 - 8.6 6.8 19.4 4.2 7.8 1.2 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein Dynamin_N PF00350.18 CDJ70409.1 - 8.8 6.1 19.9 3.2 7.5 4.9 2.1 2 0 0 2 2 2 0 Dynamin family TCP PF03634.8 CDJ70409.1 - 9.2 6.6 33.1 1.5 9.1 5.2 2.4 2 0 0 2 2 2 0 TCP family transcription factor Pap_E4 PF02711.9 CDJ70409.1 - 9.3 7.1 29.3 2.7 8.8 8.4 2.4 2 0 0 2 2 2 0 E4 protein DHHW PF14286.1 CDJ70409.1 - 9.9 5.3 24.8 1.1 8.5 6.6 2.0 2 0 0 2 2 2 0 DHHW protein APC10 PF03256.11 CDJ70411.1 - 8e-24 84.3 0.0 3.8e-23 82.0 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CDJ70411.1 - 0.032 14.0 0.5 0.056 13.2 0.0 1.8 2 1 0 2 2 2 0 F5/8 type C domain SR-25 PF10500.4 CDJ70411.1 - 0.66 9.4 8.1 0.95 8.8 5.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIF_beta PF02270.10 CDJ70412.1 - 1.1e-09 38.4 0.1 1.3e-05 25.1 0.0 2.1 2 0 0 2 2 2 2 Transcription initiation factor IIF, beta subunit Ribosomal_L22 PF00237.14 CDJ70413.1 - 0.0015 18.4 0.0 0.0065 16.3 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein L22p/L17e SR-25 PF10500.4 CDJ70413.1 - 1.7 8.0 21.1 3.3 7.1 14.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.6 CDJ70413.1 - 4.5 5.2 10.9 6.1 4.8 7.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 CDJ70415.1 - 0.069 12.6 7.7 0.1 12.0 5.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4131 PF13567.1 CDJ70415.1 - 3.2 7.1 14.9 0.61 9.4 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Med15 PF09606.5 CDJ70416.1 - 1.2 7.2 26.6 1.3 7.1 18.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ70416.1 - 1.2 8.9 20.6 1.6 8.5 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAGA-Tad1 PF12767.2 CDJ70416.1 - 2.9 7.5 13.2 4.4 6.9 9.2 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4551 PF15087.1 CDJ70416.1 - 8.8 4.5 12.4 10 4.3 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ELFV_dehydrog PF00208.16 CDJ70418.1 - 2.1e-26 93.0 0.0 1.3e-25 90.4 0.0 2.0 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RAB3GAP2_N PF14655.1 CDJ70418.1 - 0.13 11.2 1.1 0.17 10.8 0.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MRP-L20 PF12824.2 CDJ70418.1 - 2.4 8.1 8.5 4.3 7.2 5.9 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Med3 PF11593.3 CDJ70418.1 - 3.3 6.8 6.8 4.6 6.3 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Jun PF03957.8 CDJ70419.1 - 4.6e-05 23.2 2.3 5.1e-05 23.1 1.6 1.1 1 0 0 1 1 1 1 Jun-like transcription factor ELFV_dehydrog PF00208.16 CDJ70419.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4613 PF15390.1 CDJ70420.1 - 0.057 11.5 2.4 0.067 11.3 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) TRL PF13146.1 CDJ70420.1 - 0.65 10.0 2.5 0.57 10.1 0.6 1.8 1 1 0 1 1 1 0 TRL-like protein family Activator_LAG-3 PF11498.3 CDJ70420.1 - 7.6 5.1 24.0 13 4.3 16.6 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RLI PF04068.10 CDJ70421.1 - 1.2e-14 53.5 5.1 2e-14 52.8 3.5 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI CDK2AP PF09806.4 CDJ70421.1 - 0.00093 19.4 2.0 0.00099 19.3 1.4 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CDJ70421.1 - 0.013 14.9 14.9 0.018 14.4 10.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.8 CDJ70421.1 - 0.037 11.9 8.5 0.036 11.9 5.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sporozoite_P67 PF05642.6 CDJ70421.1 - 0.6 7.9 4.5 0.63 7.8 3.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF755 PF05501.6 CDJ70421.1 - 0.68 10.0 17.6 1.4 9.0 12.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4653 PF15546.1 CDJ70421.1 - 0.71 9.1 5.0 0.95 8.6 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) RAP1 PF07218.6 CDJ70421.1 - 2.8 5.9 8.3 3.1 5.7 5.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Hydrolase_6 PF13344.1 CDJ70422.1 - 7.5e-27 93.1 0.0 1.8e-26 91.9 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CDJ70422.1 - 2.1e-06 28.3 0.0 3.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase XPG_I PF00867.13 CDJ70422.1 - 0.046 13.7 1.5 0.13 12.3 1.0 2.0 1 1 0 1 1 1 0 XPG I-region DUF4175 PF13779.1 CDJ70422.1 - 0.33 8.6 13.8 0.53 7.9 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 CDJ70422.1 - 0.35 10.5 4.4 0.48 10.1 3.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ClpS PF02617.12 CDJ70423.1 - 0.078 12.7 0.0 0.31 10.7 0.0 2.0 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS DUF4653 PF15546.1 CDJ70424.1 - 0.13 11.5 7.5 0.15 11.3 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) T2SM PF04612.7 CDJ70424.1 - 0.43 10.3 14.9 0.11 12.3 5.3 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Mcm10 PF09332.6 CDJ70424.1 - 1.5 8.1 9.9 1.8 7.8 6.9 1.0 1 0 0 1 1 1 0 Mcm10 replication factor REV PF00424.13 CDJ70424.1 - 1.8 8.4 11.3 2 8.3 4.6 2.4 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Kei1 PF08552.6 CDJ70424.1 - 5.6 6.5 6.2 8 6.0 4.3 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Med15 PF09606.5 CDJ70425.1 - 0.0006 18.1 83.6 0.00082 17.7 58.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDJ70426.1 - 0.59 10.5 52.5 0.072 13.4 6.1 4.5 3 1 1 4 4 4 0 60s Acidic ribosomal protein SEA PF01390.15 CDJ70426.1 - 8.9 6.0 8.1 0.85 9.3 0.1 3.1 2 1 0 2 2 2 0 SEA domain Dehydrin PF00257.14 CDJ70427.1 - 0.23 11.7 10.5 0.68 10.2 3.9 2.4 2 0 0 2 2 2 0 Dehydrin cNMP_binding PF00027.24 CDJ70429.1 - 2.2e-29 101.0 0.7 1.4e-20 72.8 0.1 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4366 PF14283.1 CDJ70429.1 - 0.041 13.2 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Memo PF01875.12 CDJ70430.1 - 5.7e-40 136.9 0.0 1.1e-39 136.0 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein B12D PF06522.6 CDJ70431.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PRA1 PF03208.14 CDJ70431.1 - 0.12 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 PRA1 family protein RskA PF10099.4 CDJ70431.1 - 0.15 11.8 5.0 0.22 11.2 3.3 1.4 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2681 PF10883.3 CDJ70431.1 - 0.25 11.5 5.1 1.5 9.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Herpes_US9 PF06072.6 CDJ70431.1 - 0.77 9.6 3.4 1.6 8.6 1.9 1.8 1 1 1 2 2 2 0 Alphaherpesvirus tegument protein US9 ECR1_N PF14382.1 CDJ70433.1 - 3.2e-06 26.3 0.1 5.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PP2C PF00481.16 CDJ70434.1 - 3.1e-43 148.0 4.2 5e-35 121.1 0.0 3.8 4 1 0 4 4 4 3 Protein phosphatase 2C Band_3_cyto PF07565.8 CDJ70434.1 - 0.0047 16.4 1.2 0.0047 16.4 0.8 2.3 2 0 0 2 2 2 1 Band 3 cytoplasmic domain SPX PF03105.14 CDJ70434.1 - 0.035 13.9 3.9 0.11 12.2 0.3 2.3 2 0 0 2 2 2 0 SPX domain PAT1 PF09770.4 CDJ70435.1 - 0.16 10.1 40.0 0.17 10.1 27.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TCP PF03634.8 CDJ70435.1 - 0.17 12.2 19.5 0.18 12.2 13.5 1.0 1 0 0 1 1 1 0 TCP family transcription factor AIF_C PF14721.1 CDJ70435.1 - 0.4 10.9 14.7 0.46 10.7 10.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FimP PF09766.4 CDJ70435.1 - 0.67 8.9 31.9 0.92 8.5 22.1 1.3 1 0 0 1 1 1 0 Fms-interacting protein Peptidase_U57 PF05582.7 CDJ70435.1 - 0.78 8.6 13.9 0.85 8.5 9.6 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Pal1 PF08316.6 CDJ70435.1 - 0.92 9.9 9.6 0.97 9.8 6.6 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein FHIPEP PF00771.15 CDJ70435.1 - 1.1 7.5 9.7 1.1 7.4 6.7 1.2 1 0 0 1 1 1 0 FHIPEP family DDHD PF02862.12 CDJ70435.1 - 1.2 8.8 18.6 1.2 8.8 12.9 1.0 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 CDJ70435.1 - 1.5 8.1 22.5 1.5 8.1 15.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SpoIIP PF07454.6 CDJ70435.1 - 2 7.4 15.4 2.1 7.4 10.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FYDLN_acid PF09538.5 CDJ70435.1 - 2 9.0 11.6 2.5 8.7 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pex14_N PF04695.8 CDJ70435.1 - 2.2 8.3 26.5 2.5 8.1 18.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AUX_IAA PF02309.11 CDJ70435.1 - 2.5 7.8 16.8 2.8 7.6 11.7 1.0 1 0 0 1 1 1 0 AUX/IAA family DUF1764 PF08576.5 CDJ70435.1 - 2.5 8.9 22.1 3.4 8.5 15.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Gti1_Pac2 PF09729.4 CDJ70435.1 - 2.7 7.8 13.3 2.9 7.7 9.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TFIIA PF03153.8 CDJ70435.1 - 2.9 7.6 32.6 2.9 7.7 22.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TraH_2 PF06871.6 CDJ70435.1 - 3.1 7.1 9.3 3.6 6.9 6.5 1.1 1 0 0 1 1 1 0 TraH_2 Tim54 PF11711.3 CDJ70435.1 - 3.1 6.2 14.9 3.5 6.1 10.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RIC3 PF15361.1 CDJ70435.1 - 3.2 7.9 17.4 3.9 7.7 12.1 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 UPF0560 PF10577.4 CDJ70435.1 - 3.2 5.8 27.7 3.4 5.8 19.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PPP4R2 PF09184.6 CDJ70435.1 - 3.4 7.1 17.5 3.4 7.1 12.1 1.0 1 0 0 1 1 1 0 PPP4R2 Band_3_cyto PF07565.8 CDJ70435.1 - 3.4 7.1 18.4 3.7 7.0 12.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pap_E4 PF02711.9 CDJ70435.1 - 3.6 8.4 14.6 4.9 8.0 10.1 1.3 1 0 0 1 1 1 0 E4 protein FLO_LFY PF01698.11 CDJ70435.1 - 3.7 6.3 19.8 3.9 6.2 13.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Pinin_SDK_memA PF04696.8 CDJ70435.1 - 3.7 7.1 33.6 4.3 6.9 23.3 1.0 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Baculo_PP31 PF05311.6 CDJ70435.1 - 3.8 6.7 17.8 3.8 6.7 12.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gag_spuma PF03276.9 CDJ70435.1 - 3.9 5.6 39.2 4.4 5.5 27.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF4045 PF13254.1 CDJ70435.1 - 4.2 6.5 17.0 4.1 6.5 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CRF1 PF10380.4 CDJ70435.1 - 4.7 7.5 12.3 5.5 7.3 8.5 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 DUF4512 PF14975.1 CDJ70435.1 - 4.8 8.0 13.0 5.8 7.8 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Dala_Dala_lig_N PF01820.16 CDJ70435.1 - 5 7.4 10.4 7.2 6.9 7.2 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Apt1 PF10351.4 CDJ70435.1 - 5.2 5.7 15.3 5.2 5.8 10.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Med15 PF09606.5 CDJ70435.1 - 5.4 5.0 57.3 5.8 4.9 39.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FemAB PF02388.11 CDJ70435.1 - 5.4 5.5 21.2 5 5.6 14.7 1.0 1 0 0 1 1 1 0 FemAB family BORG_CEP PF14957.1 CDJ70435.1 - 5.6 7.9 11.9 6.4 7.7 8.2 1.2 1 0 0 1 1 1 0 Cdc42 effector Raftlin PF15250.1 CDJ70435.1 - 5.8 5.3 18.1 6.3 5.2 12.5 1.0 1 0 0 1 1 1 0 Raftlin PH_4 PF15404.1 CDJ70435.1 - 5.9 6.3 15.0 7.6 6.0 10.4 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Herpes_DNAp_acc PF04929.7 CDJ70435.1 - 6.1 5.6 17.6 6.4 5.6 12.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Serinc PF03348.10 CDJ70435.1 - 6.5 5.3 18.8 6.9 5.2 13.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FixO PF02433.10 CDJ70435.1 - 6.7 6.0 10.5 7.4 5.8 7.3 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO AAA_11 PF13086.1 CDJ70435.1 - 6.8 6.1 18.4 6.8 6.1 12.7 1.0 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.4 CDJ70435.1 - 7 6.5 11.0 7.7 6.4 7.6 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Paf1 PF03985.8 CDJ70435.1 - 7.3 5.2 26.3 7.6 5.1 18.2 1.0 1 0 0 1 1 1 0 Paf1 SeqA PF03925.8 CDJ70435.1 - 7.5 6.2 16.8 8.3 6.0 11.6 1.1 1 0 0 1 1 1 0 SeqA protein FAM60A PF15396.1 CDJ70435.1 - 7.5 6.2 14.6 7.9 6.1 10.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF966 PF06136.8 CDJ70435.1 - 7.5 5.8 17.4 7.4 5.8 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDJ70435.1 - 7.8 6.3 12.8 8.9 6.1 8.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med19 PF10278.4 CDJ70435.1 - 8.2 6.0 16.4 8.9 5.9 11.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 WBS_methylT PF12589.3 CDJ70435.1 - 8.6 6.9 23.8 13 6.3 16.5 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Hid1 PF12722.2 CDJ70435.1 - 9 3.8 21.7 9 3.8 15.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ARD PF03079.9 CDJ70435.1 - 9.1 6.2 11.5 9.7 6.1 8.0 1.1 1 0 0 1 1 1 0 ARD/ARD' family PIH1 PF08190.7 CDJ70435.1 - 9.3 5.5 24.3 9.2 5.5 16.9 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF4484 PF14831.1 CDJ70435.1 - 9.5 6.2 12.9 11 6.0 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) FNIP_N PF14636.1 CDJ70435.1 - 9.6 6.6 18.0 11 6.5 12.4 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus GAGA_bind PF06217.7 CDJ70435.1 - 9.7 6.0 18.5 10 6.0 12.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF605 PF04652.11 CDJ70435.1 - 9.8 5.4 26.4 11 5.3 18.3 1.0 1 0 0 1 1 1 0 Vta1 like Claudin_2 PF13903.1 CDJ70436.1 - 0.059 13.0 0.2 0.059 13.0 0.2 3.6 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Suf PF05843.9 CDJ70436.1 - 0.2 11.3 20.3 1.9 8.1 9.0 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ70436.1 - 5.7 6.7 41.7 0.53 10.1 13.6 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 CDJ70436.1 - 7.6 5.8 22.3 0.18 11.1 8.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 CDJ70437.1 - 0.1 11.0 46.3 0.005 15.3 18.6 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 BAF1_ABF1 PF04684.8 CDJ70437.1 - 2.5 6.8 52.1 0.2 10.4 19.7 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF1510 PF07423.6 CDJ70437.1 - 3 7.1 36.2 0.9 8.8 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 CDJ70437.1 - 3.1 7.2 26.8 0.33 10.4 9.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Kelch_1 PF01344.20 CDJ70439.1 - 7.9e-16 57.3 0.2 1.1e-09 37.6 0.0 4.1 4 0 0 4 4 3 2 Kelch motif Kelch_6 PF13964.1 CDJ70439.1 - 1.9e-10 40.4 0.0 3.8e-07 29.9 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CDJ70439.1 - 5e-05 22.9 0.0 0.0019 17.8 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CDJ70439.1 - 0.0013 18.4 0.0 0.0077 15.9 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 CDJ70439.1 - 0.003 17.6 2.4 0.0058 16.7 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CDJ70439.1 - 0.022 14.6 0.0 7.2 6.6 0.0 3.2 3 0 0 3 3 3 0 Kelch motif Zip PF02535.17 CDJ70439.1 - 0.065 12.2 1.7 0.1 11.5 1.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CDJ70439.1 - 0.12 12.1 13.9 0.22 11.2 9.7 1.3 1 0 0 1 1 1 0 DDHD domain Pet20 PF08692.5 CDJ70439.1 - 0.2 11.6 2.2 0.3 11.0 1.1 1.6 1 1 1 2 2 2 0 Mitochondrial protein Pet20 DHHW PF14286.1 CDJ70439.1 - 2 7.6 10.3 3.3 6.9 7.1 1.3 1 0 0 1 1 1 0 DHHW protein DUF1675 PF07897.6 CDJ70439.1 - 2.4 7.9 10.7 4.9 6.9 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDC45 PF02724.9 CDJ70439.1 - 2.9 5.8 13.4 4 5.3 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3552 PF12072.3 CDJ70440.1 - 0.21 10.7 0.3 0.37 9.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Chromo PF00385.19 CDJ70441.1 - 9e-14 50.8 0.0 1.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDJ70441.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain SprA-related PF12118.3 CDJ70442.1 - 0.0014 17.9 47.7 0.0014 17.9 33.0 6.9 5 2 0 5 5 5 1 SprA-related family SprA-related PF12118.3 CDJ70443.1 - 0.0024 17.2 48.2 0.0024 17.2 33.4 7.8 5 2 0 6 6 6 1 SprA-related family Conotoxin PF02950.12 CDJ70443.1 - 4.3 8.2 0.0 4.3 8.2 0.0 7.6 6 1 2 8 8 8 0 Conotoxin BLVR PF06375.6 CDJ70444.1 - 0.00092 19.0 1.0 0.00092 19.0 0.7 4.2 2 1 1 3 3 3 1 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 CDJ70444.1 - 0.013 14.9 17.9 0.013 14.9 12.4 4.0 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein Conotoxin PF02950.12 CDJ70444.1 - 0.024 15.4 5.3 0.024 15.4 3.7 5.7 3 1 0 3 3 3 0 Conotoxin Ribosomal_60s PF00428.14 CDJ70444.1 - 0.24 11.8 14.1 0.056 13.8 6.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Amidohydro_2 PF04909.9 CDJ70444.1 - 0.38 10.2 4.2 0.8 9.2 2.6 1.7 1 1 0 1 1 1 0 Amidohydrolase Med3 PF11593.3 CDJ70445.1 - 5.2e-05 22.6 15.3 5.2e-05 22.6 10.6 3.4 2 1 1 3 3 3 1 Mediator complex subunit 3 fungal FKBP_C PF00254.23 CDJ70445.1 - 0.00038 20.4 0.0 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Med15 PF09606.5 CDJ70445.1 - 0.91 7.6 42.0 0.021 13.0 17.3 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ70445.1 - 8.5 6.1 37.9 2.9 7.6 5.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Dopey_N PF04118.9 CDJ70446.1 - 2.1e-27 95.6 2.8 2.4e-27 95.5 0.0 2.4 3 0 0 3 3 3 1 Dopey, N-terminal Bromodomain PF00439.20 CDJ70447.1 - 4.4e-13 48.9 0.0 1.1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain DnaG_DnaB_bind PF08278.6 CDJ70448.1 - 3 8.0 10.3 0.56 10.4 3.8 2.1 1 1 0 2 2 2 0 DNA primase DnaG DnaB-binding Chorion_2 PF03964.10 CDJ70450.1 - 0.00021 21.7 15.0 0.00024 21.6 1.0 2.4 2 0 0 2 2 2 1 Chorion family 2 CDK2AP PF09806.4 CDJ70450.1 - 0.19 11.9 14.7 0.27 11.4 2.5 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDJ70450.1 - 0.47 10.8 15.7 0.26 11.7 4.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Secretin_N_2 PF07655.8 CDJ70450.1 - 0.63 10.4 12.3 0.36 11.2 2.3 2.6 3 0 0 3 3 3 0 Secretin N-terminal domain Silic_transp PF03842.8 CDJ70450.1 - 0.67 7.9 4.1 1 7.3 2.8 1.2 1 0 0 1 1 1 0 Silicon transporter MIP-T3 PF10243.4 CDJ70450.1 - 8.3 4.7 37.8 13 4.1 26.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Med15 PF09606.5 CDJ70451.1 - 0.0023 16.2 9.0 0.0023 16.2 6.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.3 CDJ70451.1 - 0.021 13.9 1.5 0.022 13.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.3 CDJ70451.1 - 0.026 13.8 0.3 0.028 13.7 0.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF912 PF06024.7 CDJ70451.1 - 0.051 13.6 0.1 0.075 13.0 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RAB3GAP2_N PF14655.1 CDJ70451.1 - 0.083 11.8 5.5 0.12 11.4 3.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med3 PF11593.3 CDJ70451.1 - 0.37 9.9 9.8 0.47 9.6 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Phostensin_N PF13916.1 CDJ70451.1 - 1.8 8.6 6.2 3.2 7.7 4.3 1.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal RRM_1 PF00076.17 CDJ70452.1 - 2.1e-06 27.2 0.2 3.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ70452.1 - 4e-05 23.4 0.1 0.00048 20.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ70452.1 - 0.0037 17.0 0.0 0.0084 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spore_coat_CotO PF14153.1 CDJ70453.1 - 0.008 15.6 27.1 0.008 15.6 18.8 2.5 2 1 0 2 2 2 1 Spore coat protein CotO Plasmodium_Vir PF05795.6 CDJ70453.1 - 5.1 6.2 15.9 0.34 10.0 6.5 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein RAP PF08373.5 CDJ70455.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 RAP domain OHA PF14418.1 CDJ70456.1 - 3.4e-18 64.8 0.0 1.7e-17 62.6 0.0 2.3 1 0 0 1 1 1 1 OST-HTH Associated domain PAT1 PF09770.4 CDJ70456.1 - 0.4 8.8 57.5 0.29 9.3 7.3 2.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF1469 PF07332.6 CDJ70457.1 - 7.5e-05 22.4 1.9 7.5e-05 22.4 1.3 5.1 4 2 1 5 5 5 1 Protein of unknown function (DUF1469) Claudin_2 PF13903.1 CDJ70457.1 - 0.00083 19.0 3.4 0.00083 19.0 2.4 5.7 2 2 2 6 6 6 1 PMP-22/EMP/MP20/Claudin tight junction Borrelia_P83 PF05262.6 CDJ70457.1 - 0.0049 15.2 0.4 0.0077 14.5 0.3 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein DUF3357 PF11837.3 CDJ70457.1 - 0.047 13.5 0.5 0.047 13.5 0.4 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF3357) O-antigen_lig PF13425.1 CDJ70457.1 - 0.071 13.0 0.0 0.071 13.0 0.0 3.5 4 1 0 4 4 4 0 O-antigen ligase like membrane protein Hid1 PF12722.2 CDJ70457.1 - 1.2 6.7 6.4 1.5 6.3 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3260 PF11658.3 CDJ70457.1 - 1.2 7.1 8.2 2.3 6.2 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Macoilin PF09726.4 CDJ70457.1 - 1.8 6.7 10.1 2.9 6.0 7.0 1.2 1 0 0 1 1 1 0 Transmembrane protein EphA2_TM PF14575.1 CDJ70457.1 - 6 7.3 9.9 0.19 12.1 0.3 3.1 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DDHD PF02862.12 CDJ70458.1 - 6 6.6 8.5 6.1 6.5 5.9 1.0 1 0 0 1 1 1 0 DDHD domain SART-1 PF03343.8 CDJ70458.1 - 8.3 4.6 11.1 9 4.5 7.7 1.0 1 0 0 1 1 1 0 SART-1 family Peptidase_S49_N PF08496.5 CDJ70458.1 - 8.9 6.0 8.3 8.1 6.2 5.8 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ADK PF00406.17 CDJ70459.1 - 7.1e-10 38.9 0.5 7.1e-10 38.9 0.3 2.7 2 1 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 CDJ70459.1 - 0.00022 21.1 1.1 0.00022 21.1 0.8 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDJ70459.1 - 0.0025 18.6 0.0 0.0046 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain U1snRNP70_N PF12220.3 CDJ70459.1 - 0.0035 17.6 15.9 0.0035 17.6 11.0 2.7 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SPX PF03105.14 CDJ70459.1 - 0.0076 16.0 10.2 0.19 11.5 5.1 2.0 2 0 0 2 2 2 1 SPX domain DUF4483 PF14825.1 CDJ70459.1 - 0.015 14.9 7.2 0.015 14.9 5.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) Dpy-30 PF05186.8 CDJ70459.1 - 0.029 13.8 0.9 0.059 12.8 0.6 1.5 1 0 0 1 1 1 0 Dpy-30 motif Med15 PF09606.5 CDJ70459.1 - 0.032 12.4 55.6 0.054 11.7 38.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Folliculin PF11704.3 CDJ70459.1 - 0.1 12.1 8.3 0.25 10.9 2.0 2.5 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport RNA_lig_T4_1 PF09511.5 CDJ70459.1 - 0.11 11.9 3.5 0.17 11.2 2.4 1.3 1 0 0 1 1 1 0 RNA ligase GPCR_chapero_1 PF11904.3 CDJ70459.1 - 0.3 10.1 11.1 0.52 9.3 7.7 1.3 1 0 0 1 1 1 0 GPCR-chaperone Peptidase_S49_N PF08496.5 CDJ70459.1 - 0.39 10.5 13.3 0.86 9.3 5.2 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peroxin-13_N PF04088.8 CDJ70459.1 - 0.47 10.3 4.0 0.27 11.1 0.4 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2076 PF09849.4 CDJ70459.1 - 0.54 10.2 40.8 1.6 8.7 13.8 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) GerA PF03323.8 CDJ70459.1 - 0.78 7.8 6.1 6.3 4.8 2.1 2.0 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF2803 PF10972.3 CDJ70459.1 - 1.3 8.5 20.2 2.5 7.5 13.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2803) Ndc1_Nup PF09531.5 CDJ70459.1 - 1.8 6.8 14.2 2.5 6.4 9.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4557 PF15101.1 CDJ70459.1 - 2.1 8.1 28.6 1.6 8.5 12.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) RR_TM4-6 PF06459.7 CDJ70459.1 - 2.4 7.9 15.4 0.61 9.9 6.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Baculo_PP31 PF05311.6 CDJ70459.1 - 2.7 7.1 13.7 0.38 9.9 4.6 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) SpoIIP PF07454.6 CDJ70459.1 - 2.9 6.9 12.3 0.65 9.1 4.4 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2072 PF09845.4 CDJ70459.1 - 3.6 7.5 6.9 1.5 8.7 1.3 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DUF3408 PF11888.3 CDJ70459.1 - 4.5 7.1 15.1 11 5.8 7.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF912 PF06024.7 CDJ70459.1 - 5.8 7.0 9.1 6.3 6.9 3.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Radial_spoke PF04712.7 CDJ70459.1 - 6.1 5.4 18.7 0.44 9.2 8.7 1.9 2 0 0 2 2 2 0 Radial spokehead-like protein Bud13 PF09736.4 CDJ70459.1 - 7.4 6.8 20.1 2.7 8.2 8.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex AAA_28 PF13521.1 CDJ70459.1 - 7.6 6.4 10.3 25 4.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain FLO_LFY PF01698.11 CDJ70459.1 - 8.8 5.0 12.3 0.96 8.2 3.7 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF4200 PF13863.1 CDJ70460.1 - 1.3e-11 44.5 46.2 6.3e-11 42.3 15.7 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Herpes_capsid PF06112.6 CDJ70460.1 - 0.0077 16.2 17.1 0.0084 16.1 8.5 2.6 2 0 0 2 2 2 1 Gammaherpesvirus capsid protein Kinesin PF00225.18 CDJ70462.1 - 3.6e-30 104.8 0.2 4.3e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain PIF1 PF05970.9 CDJ70462.1 - 0.00088 18.3 0.1 0.0014 17.6 0.1 1.3 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 CDJ70462.1 - 0.011 15.5 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CDJ70462.1 - 0.053 12.7 0.1 0.074 12.2 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Prokineticin PF06607.6 CDJ70463.1 - 0.052 13.6 0.5 0.096 12.7 0.3 1.4 1 0 0 1 1 1 0 Prokineticin DUF2985 PF11204.3 CDJ70463.1 - 0.078 12.7 4.0 0.1 12.3 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2985) DUF92 PF01940.11 CDJ70463.1 - 0.87 8.6 5.4 2 7.5 3.7 1.6 1 1 0 1 1 1 0 Integral membrane protein DUF92 Tweety PF04906.8 CDJ70463.1 - 4.9 5.4 10.5 3.8 5.8 5.9 1.8 1 1 0 1 1 1 0 Tweety FimP PF09766.4 CDJ70464.1 - 0.00032 19.9 6.0 0.00032 19.9 4.2 2.1 2 0 0 2 2 2 1 Fms-interacting protein BAF1_ABF1 PF04684.8 CDJ70464.1 - 0.008 15.0 20.8 0.008 15.0 14.4 5.9 3 2 1 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor DUF3371 PF11851.3 CDJ70464.1 - 0.024 15.3 14.6 0.024 15.3 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Spt20 PF12090.3 CDJ70464.1 - 0.4 10.0 13.5 0.037 13.3 2.2 2.2 2 0 0 2 2 2 0 Spt20 family Dynamin_N PF00350.18 CDJ70464.1 - 0.45 10.3 6.7 0.26 11.0 2.9 1.8 2 0 0 2 2 2 0 Dynamin family Activator_LAG-3 PF11498.3 CDJ70464.1 - 2 7.0 39.4 1 8.0 17.6 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Peptidase_S49_N PF08496.5 CDJ70464.1 - 2.8 7.7 11.1 0.42 10.3 3.4 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF912 PF06024.7 CDJ70464.1 - 7.6 6.6 7.4 5.2 7.1 1.3 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Bul1_N PF04425.7 CDJ70464.1 - 9.4 4.6 9.7 0.68 8.4 3.2 1.5 2 0 0 2 2 2 0 Bul1 N terminus SprA-related PF12118.3 CDJ70466.1 - 1.8 7.7 37.7 0.61 9.3 18.1 2.0 2 0 0 2 2 2 0 SprA-related family Aminotran_5 PF00266.14 CDJ70468.1 - 3.5e-36 124.7 0.0 4e-22 78.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.16 CDJ70468.1 - 0.0063 15.5 0.0 0.073 12.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CDJ70468.1 - 0.12 10.5 0.1 0.2 9.8 0.1 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Secretin_N_2 PF07655.8 CDJ70468.1 - 1.9 8.9 14.3 0.37 11.2 4.3 2.6 3 0 0 3 3 3 0 Secretin N-terminal domain DUF1675 PF07897.6 CDJ70469.1 - 0.054 13.3 10.5 0.065 13.0 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDK5_activator PF03261.10 CDJ70469.1 - 0.072 12.4 9.0 0.083 12.2 6.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein VID27 PF08553.5 CDJ70469.1 - 0.16 10.1 2.7 0.18 9.9 1.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein MTBP_C PF14920.1 CDJ70469.1 - 0.17 11.3 14.7 0.22 10.9 10.2 1.1 1 0 0 1 1 1 0 MDM2-binding FLO_LFY PF01698.11 CDJ70469.1 - 0.23 10.2 2.8 0.24 10.2 1.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF605 PF04652.11 CDJ70469.1 - 0.25 10.6 18.9 0.3 10.4 13.1 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CDJ70469.1 - 0.36 9.0 22.9 0.39 8.9 15.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDJ70469.1 - 0.41 10.4 8.1 0.49 10.1 5.6 1.1 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 CDJ70469.1 - 0.41 8.7 28.0 0.47 8.5 19.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDJ70469.1 - 0.71 9.7 16.6 0.79 9.5 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF566 PF04484.7 CDJ70469.1 - 0.72 9.3 16.7 0.83 9.1 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) CDC45 PF02724.9 CDJ70469.1 - 0.74 7.7 6.0 0.9 7.4 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CAF-1_p150 PF11600.3 CDJ70469.1 - 0.77 9.0 16.1 1 8.6 11.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAGA-Tad1 PF12767.2 CDJ70469.1 - 0.9 9.1 12.0 1 8.9 8.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4407 PF14362.1 CDJ70469.1 - 0.94 8.3 6.7 1.1 8.1 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.12 CDJ70469.1 - 2 7.1 7.2 2.3 6.9 5.0 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.2 CDJ70469.1 - 2.1 5.9 9.6 2.2 5.8 6.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spc7_N PF15402.1 CDJ70469.1 - 2.6 5.9 16.1 2.9 5.7 11.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SR-25 PF10500.4 CDJ70469.1 - 2.8 7.3 24.3 6.3 6.1 16.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein GPCR_chapero_1 PF11904.3 CDJ70469.1 - 3.3 6.7 8.4 4 6.4 5.8 1.0 1 0 0 1 1 1 0 GPCR-chaperone Mif2_N PF15624.1 CDJ70469.1 - 5.6 7.5 11.4 7.7 7.1 7.9 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Serinc PF03348.10 CDJ70469.1 - 6.6 5.3 8.1 8.1 5.0 5.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) 7TM_transglut PF14402.1 CDJ70469.1 - 6.9 5.4 6.6 12 4.7 3.3 1.8 1 1 1 2 2 2 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF2201_N PF13203.1 CDJ70469.1 - 8.1 5.5 14.3 10 5.2 9.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Gag_spuma PF03276.9 CDJ70469.1 - 8.9 4.5 19.0 9.9 4.3 13.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Baculo_PP31 PF05311.6 CDJ70469.1 - 9.2 5.4 7.6 12 5.1 5.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) GTP_EFTU PF00009.22 CDJ70470.1 - 1.2e-07 31.3 1.6 3.1e-07 29.9 1.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TFIIA PF03153.8 CDJ70471.1 - 0.022 14.6 14.6 0.03 14.2 10.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDJ70471.1 - 0.1 10.8 38.9 0.15 10.1 27.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDJ70471.1 - 0.17 11.2 9.4 0.75 9.1 0.3 2.2 2 0 0 2 2 2 0 Spt20 family DUF2376 PF09550.5 CDJ70471.1 - 0.42 10.7 0.1 0.42 10.7 0.0 2.5 2 1 0 2 2 2 0 Conserved hypothetical phage protein (DUF2376) PsbW PF07123.7 CDJ70471.1 - 0.54 10.3 13.1 0.026 14.5 3.5 2.1 1 1 1 2 2 2 0 Photosystem II reaction centre W protein (PsbW) DUF572 PF04502.8 CDJ70471.1 - 1.3 8.1 8.2 2.2 7.4 5.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) IpaD PF06511.6 CDJ70471.1 - 4.8 6.0 10.7 7.5 5.4 7.4 1.3 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD PsbQ PF05757.6 CDJ70471.1 - 7.7 5.8 17.0 15 4.9 11.5 1.7 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Spc24 PF08286.6 CDJ70472.1 - 0.12 12.1 5.5 1.1 9.0 1.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FAM195 PF14799.1 CDJ70472.1 - 0.48 10.3 9.5 0.066 13.0 1.9 2.2 2 0 0 2 2 2 0 FAM195 family TFIIA PF03153.8 CDJ70472.1 - 0.74 9.6 14.2 0.97 9.2 9.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HlyD_2 PF12700.2 CDJ70472.1 - 2.4 7.2 6.2 3.2 6.8 4.3 1.2 1 0 0 1 1 1 0 HlyD family secretion protein p25-alpha PF05517.7 CDJ70473.1 - 4.2e-35 121.2 0.2 4.7e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 p25-alpha SurA_N PF09312.6 CDJ70473.1 - 0.0051 16.6 0.2 0.0072 16.1 0.1 1.2 1 0 0 1 1 1 1 SurA N-terminal domain RHH_4 PF13467.1 CDJ70473.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain SET PF00856.23 CDJ70474.1 - 1.6e-09 38.2 8.8 2.8e-06 27.7 0.0 2.9 3 1 0 3 3 3 2 SET domain RPAP2_Rtr1 PF04181.8 CDJ70474.1 - 0.04 14.0 0.7 0.04 14.0 0.5 3.2 3 0 0 3 3 3 0 Rtr1/RPAP2 family Spt20 PF12090.3 CDJ70474.1 - 0.063 12.6 10.1 0.81 9.0 0.8 2.2 2 0 0 2 2 2 0 Spt20 family DUF912 PF06024.7 CDJ70474.1 - 1.2 9.2 5.3 4.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2763 PF10961.3 CDJ70475.1 - 0.0032 17.8 0.7 0.0062 16.8 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2763) SR-25 PF10500.4 CDJ70475.1 - 6.5 6.1 12.9 11 5.3 8.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cpn60_TCP1 PF00118.19 CDJ70477.1 - 2e-50 171.8 0.1 2.9e-29 102.0 0.0 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family CHD5 PF04420.9 CDJ70478.1 - 5.6e-08 32.6 4.5 9.8e-08 31.8 3.1 1.4 1 0 0 1 1 1 1 CHD5-like protein DUF342 PF03961.8 CDJ70478.1 - 0.25 9.7 4.3 0.33 9.3 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 CDJ70478.1 - 1.5 8.4 16.3 2.3 7.8 11.3 1.2 1 0 0 1 1 1 0 Mnd1 family AAA_23 PF13476.1 CDJ70478.1 - 1.7 8.9 9.6 2.6 8.3 6.7 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_S46 PF10459.4 CDJ70478.1 - 1.7 6.9 6.8 2.3 6.5 4.7 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF572 PF04502.8 CDJ70478.1 - 4.9 6.2 15.4 4.8 6.2 9.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF572) dsDNA_bind PF01984.15 CDJ70479.1 - 3.2e-23 81.7 12.8 4e-23 81.4 8.9 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4332 PF14229.1 CDJ70479.1 - 0.014 15.3 1.7 0.021 14.7 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4332) TrbH PF07283.6 CDJ70479.1 - 0.067 13.0 0.3 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbH PALP PF00291.20 CDJ70479.1 - 0.09 11.9 0.8 0.11 11.7 0.6 1.0 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF3385 PF11865.3 CDJ70479.1 - 0.16 11.9 2.0 0.26 11.2 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) Med15 PF09606.5 CDJ70479.1 - 0.23 9.6 11.9 0.25 9.5 8.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3886 PF13025.1 CDJ70479.1 - 3 7.8 13.2 3.2 7.7 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Cut8_N PF14482.1 CDJ70479.1 - 6.7 6.7 8.5 4.8 7.2 0.4 2.5 2 0 0 2 2 2 0 Cut8 proteasome-binding domain APC_CDC26 PF10471.4 CDJ70480.1 - 9.3 7.0 19.6 0.51 11.1 1.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3801 PF12687.2 CDJ70481.1 - 3.2 7.2 18.9 0.011 15.2 1.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) Dapper PF15268.1 CDJ70482.1 - 8.5 5.0 35.8 9.4 4.8 24.8 1.0 1 0 0 1 1 1 0 Dapper SpoIIIAH PF12685.2 CDJ70483.1 - 0.072 12.5 0.4 0.091 12.2 0.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1216 PF06746.6 CDJ70483.1 - 0.12 12.1 6.1 0.24 11.1 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) BNIP3 PF06553.7 CDJ70483.1 - 0.2 11.0 4.5 0.35 10.2 3.1 1.5 1 1 0 1 1 1 0 BNIP3 DUF3774 PF12609.3 CDJ70483.1 - 0.26 12.1 11.2 0.13 13.1 2.5 2.3 2 0 0 2 2 2 0 Wound-induced protein CDK2AP PF09806.4 CDJ70484.1 - 0.012 15.8 14.8 0.017 15.4 10.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DNA_pol_viral_N PF00242.12 CDJ70484.1 - 0.49 9.3 12.8 0.53 9.2 8.9 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ARF7EP_C PF14949.1 CDJ70484.1 - 2 8.9 8.5 4.7 7.6 5.9 1.6 1 1 0 1 1 1 0 ARF7 effector protein C-terminus TAF4 PF05236.9 CDJ70484.1 - 5 6.3 14.9 1.6 7.9 2.5 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MDFI PF15316.1 CDJ70484.1 - 9.4 6.1 11.3 13 5.7 7.8 1.1 1 0 0 1 1 1 0 MyoD family inhibitor MutS_III PF05192.13 CDJ70485.1 - 1.8e-06 27.8 10.8 0.00071 19.4 0.8 3.0 3 0 0 3 3 3 2 MutS domain III Med3 PF11593.3 CDJ70485.1 - 9.1 5.3 14.6 15 4.7 10.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_2 PF07724.9 CDJ70486.1 - 3.2e-24 85.7 0.0 6.9e-23 81.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CDJ70486.1 - 4e-15 55.4 0.0 7.2e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CDJ70486.1 - 0.00034 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) P63C PF10546.4 CDJ70486.1 - 0.064 13.1 0.1 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 P63C domain Cut8_M PF14483.1 CDJ70487.1 - 0.039 13.7 0.1 1.4e+02 2.3 0.0 4.2 4 0 0 4 4 4 0 Cut8 dimerisation domain Histone_HNS PF00816.16 CDJ70487.1 - 0.14 12.6 0.8 0.86 10.1 0.1 2.6 4 0 0 4 4 4 0 H-NS histone family VPS9 PF02204.13 CDJ70489.1 - 1.2e-23 83.0 0.0 2.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain TFIIA PF03153.8 CDJ70490.1 - 0.18 11.6 37.9 0.25 11.2 26.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.8 CDJ70490.1 - 0.37 8.9 26.1 0.45 8.6 18.1 1.0 1 0 0 1 1 1 0 Utp14 protein Glyco_transf_20 PF00982.16 CDJ70490.1 - 1.8 6.9 10.8 1.3 7.4 6.8 1.3 1 1 0 1 1 1 0 Glycosyltransferase family 20 RskA PF10099.4 CDJ70490.1 - 1.9 8.2 34.8 0.017 14.8 8.6 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA SOBP PF15279.1 CDJ70490.1 - 2.3 8.5 16.9 2.9 8.2 11.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FLO_LFY PF01698.11 CDJ70490.1 - 3.2 6.4 18.5 4.6 5.9 12.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein GCC2_GCC3 PF07699.8 CDJ70491.1 - 3.3e-15 55.3 146.9 0.00026 20.4 1.7 16.1 11 5 4 15 15 15 9 GCC2 and GCC3 NCD3G PF07562.9 CDJ70491.1 - 0.024 14.3 0.3 0.024 14.3 0.2 12.4 11 1 0 11 11 11 0 Nine Cysteines Domain of family 3 GPCR IL33 PF15095.1 CDJ70491.1 - 0.22 10.9 0.0 0.22 10.9 0.0 2.8 3 0 0 3 3 3 0 Interleukin 33 DUF2722 PF10846.3 CDJ70491.1 - 1.1 8.1 37.5 1.3 7.9 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) zf-CCHC PF00098.18 CDJ70492.1 - 1.5e-05 24.7 9.9 0.0022 17.8 0.9 2.4 2 0 0 2 2 2 2 Zinc knuckle Retrotrans_gag PF03732.12 CDJ70492.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_6 PF15288.1 CDJ70492.1 - 0.087 12.5 0.4 0.087 12.5 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDJ70492.1 - 0.15 12.1 9.6 0.63 10.1 6.7 1.9 1 1 0 1 1 1 0 DnaJ central domain zf-CCHC_3 PF13917.1 CDJ70492.1 - 0.45 10.2 6.3 0.56 9.9 0.6 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDJ70492.1 - 1.5 8.5 6.1 4.5 7.0 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF4208 PF13907.1 CDJ70495.1 - 2.4 8.4 5.7 15 5.8 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) FliJ PF02050.11 CDJ70495.1 - 2.4 8.2 8.8 0.51 10.3 2.3 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.11 CDJ70496.1 - 1.2e-21 76.8 16.9 1.7e-21 76.3 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CDJ70496.1 - 5.5e-05 21.7 3.3 0.012 14.0 0.0 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Intg_mem_TP0381 PF09529.5 CDJ70496.1 - 0.0049 16.1 0.7 1.1 8.5 0.1 2.3 2 0 0 2 2 2 2 Integral membrane protein (intg_mem_TP0381) IR1-M PF12185.3 CDJ70496.1 - 0.064 12.9 0.1 3.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain PolyA_pol PF01743.15 CDJ70498.1 - 2.8e-21 76.0 1.0 1e-20 74.1 0.0 2.5 4 0 0 4 4 4 1 Poly A polymerase head domain Mito_carr PF00153.22 CDJ70502.1 - 6.2e-23 80.3 0.3 5.9e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein NIF PF03031.13 CDJ70503.1 - 1.8e-44 151.1 0.2 2.7e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IncA PF04156.9 CDJ70506.1 - 0.0048 16.5 3.0 0.0048 16.5 2.1 1.9 2 0 0 2 2 2 1 IncA protein APC_CDC26 PF10471.4 CDJ70506.1 - 0.19 12.4 18.9 1.3 9.8 1.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 FAM60A PF15396.1 CDJ70506.1 - 0.27 10.9 3.3 0.39 10.4 2.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.3 CDJ70506.1 - 0.32 9.5 6.0 0.45 9.0 4.1 1.3 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1183 PF06682.7 CDJ70506.1 - 0.49 9.9 5.4 0.71 9.4 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) GAPT PF11770.3 CDJ70506.1 - 1.6 8.3 7.4 0.16 11.6 1.6 1.8 2 1 0 2 2 2 0 GRB2-binding adapter (GAPT) Med15 PF09606.5 CDJ70506.1 - 2 6.5 28.3 2.5 6.1 19.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDJ70506.1 - 2.2 7.9 12.7 2.9 7.5 8.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDJ70506.1 - 7 6.4 17.9 9.7 5.9 12.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dehydrin PF00257.14 CDJ70506.1 - 8.1 6.7 12.3 4.5 7.5 1.5 2.0 2 0 0 2 2 2 0 Dehydrin SR-25 PF10500.4 CDJ70507.1 - 0.0047 16.4 2.2 0.0047 16.4 1.5 8.8 4 2 2 6 6 6 2 Nuclear RNA-splicing-associated protein XRCC4 PF06632.7 CDJ70508.1 - 0.8 8.4 7.7 1.1 8.0 5.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Rifin_STEVOR PF02009.11 CDJ70508.1 - 1.3 8.6 9.1 2 8.0 6.3 1.4 1 1 0 1 1 1 0 Rifin/stevor family DUF3753 PF12575.3 CDJ70508.1 - 3.8 7.3 5.4 1.2 8.9 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF3533 PF12051.3 CDJ70508.1 - 4.9 5.8 11.5 5.7 5.5 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) EphA2_TM PF14575.1 CDJ70508.1 - 9.2 6.7 7.8 0.96 9.8 0.2 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RabGAP-TBC PF00566.13 CDJ70509.1 - 3.2e-27 95.4 0.1 3.2e-27 95.4 0.1 2.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GCC2_GCC3 PF07699.8 CDJ70511.1 - 6.8e-05 22.3 2.5 6.8e-05 22.3 1.7 4.3 2 2 2 4 4 4 3 GCC2 and GCC3 NCD3G PF07562.9 CDJ70511.1 - 0.22 11.2 13.5 0.14 11.8 0.6 3.4 2 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Med3 PF11593.3 CDJ70513.1 - 3.1 6.9 17.5 1.5 7.9 2.6 3.2 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal APC_CDC26 PF10471.4 CDJ70513.1 - 5 7.9 20.3 2.7 8.7 3.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 TFIIA PF03153.8 CDJ70513.1 - 7.8 6.2 15.4 12 5.6 10.3 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDJ70513.1 - 10 4.2 17.8 15 3.6 12.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDJ70514.1 - 0.00016 21.9 4.0 0.00025 21.4 2.7 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein RskA PF10099.4 CDJ70514.1 - 0.29 10.8 4.3 0.38 10.4 3.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3617 PF12276.3 CDJ70514.1 - 1.7 8.0 5.9 2.5 7.5 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Shadoo PF14999.1 CDJ70514.1 - 5.6 6.8 11.7 8.5 6.2 8.1 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective TFIIA PF03153.8 CDJ70516.1 - 0.0031 17.4 36.8 0.0045 16.9 25.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CDJ70516.1 - 0.0038 16.6 22.7 0.0046 16.3 15.7 1.1 1 0 0 1 1 1 1 Vta1 like DUF4401 PF14351.1 CDJ70516.1 - 0.0042 16.1 0.7 0.0042 16.1 0.5 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4401) SR-25 PF10500.4 CDJ70516.1 - 0.0077 15.7 23.1 0.012 15.0 16.0 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4131 PF13567.1 CDJ70516.1 - 0.013 14.9 0.9 0.013 14.9 0.6 2.9 2 1 0 2 2 1 0 Domain of unknown function (DUF4131) CDC27 PF09507.5 CDJ70516.1 - 0.14 11.3 24.6 0.19 10.9 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.5 CDJ70516.1 - 0.15 10.4 19.4 0.18 10.2 13.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF966 PF06136.8 CDJ70516.1 - 0.33 10.3 23.0 0.43 9.9 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TAF1D PF15333.1 CDJ70516.1 - 0.38 10.4 18.9 0.6 9.8 13.1 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Parvo_coat PF00740.13 CDJ70516.1 - 1 8.2 20.4 1.3 7.8 14.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Presenilin PF01080.12 CDJ70516.1 - 1.3 7.7 20.3 62 2.2 14.1 2.0 1 1 0 1 1 1 0 Presenilin Herpes_LMP2 PF07415.6 CDJ70516.1 - 2.5 6.6 12.5 0.016 13.8 0.4 2.1 1 1 1 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Draxin PF15550.1 CDJ70516.1 - 2.9 7.4 25.1 3.9 7.0 17.4 1.2 1 0 0 1 1 1 0 Draxin SOBP PF15279.1 CDJ70516.1 - 3.3 8.0 26.1 4.7 7.5 18.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 CDJ70516.1 - 3.6 5.7 24.8 5.3 5.1 17.2 1.2 1 0 0 1 1 1 0 Transmembrane protein PLRV_ORF5 PF01690.12 CDJ70516.1 - 6.9 5.6 22.2 8.6 5.3 15.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Borrelia_P83 PF05262.6 CDJ70516.1 - 7.3 4.7 27.3 8.9 4.4 18.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF106 PF01956.11 CDJ70516.1 - 8.7 5.8 14.4 0.2 11.1 0.6 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 zf-RING_2 PF13639.1 CDJ70517.1 - 0.047 13.5 3.2 0.26 11.1 0.0 2.4 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 CDJ70517.1 - 0.21 11.3 0.8 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDJ70517.1 - 1.5 9.0 9.3 17 5.6 6.5 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger RNA_pol_L_2 PF13656.1 CDJ70518.1 - 8.6e-08 31.5 0.1 3.9e-06 26.2 0.0 2.1 1 1 1 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RAP1 PF07218.6 CDJ70518.1 - 0.00038 18.7 2.2 0.00044 18.5 1.5 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) RNA_pol_L PF01193.19 CDJ70518.1 - 0.011 14.7 0.1 0.019 14.0 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain SprA-related PF12118.3 CDJ70518.1 - 0.015 14.6 12.8 0.021 14.1 8.9 1.2 1 0 0 1 1 1 0 SprA-related family UBN_AB PF14075.1 CDJ70518.1 - 0.024 14.3 0.3 0.029 14.0 0.2 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain TSA PF03249.8 CDJ70518.1 - 2 6.8 12.4 2.4 6.6 8.6 1.1 1 0 0 1 1 1 0 Type specific antigen FSIP1 PF15554.1 CDJ70518.1 - 2.2 6.9 13.9 3.2 6.4 9.7 1.2 1 1 0 1 1 1 0 FSIP1 family MscS_TM PF12794.2 CDJ70518.1 - 2.3 6.7 5.2 3.4 6.1 3.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4175 PF13779.1 CDJ70518.1 - 2.3 5.7 16.3 2.5 5.6 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SOBP PF15279.1 CDJ70518.1 - 2.6 8.3 7.6 3.7 7.8 5.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Pap_E4 PF02711.9 CDJ70518.1 - 5 8.0 8.5 2.4 9.0 1.1 2.1 2 0 0 2 2 2 0 E4 protein Na_trans_assoc PF06512.8 CDJ70518.1 - 6.8 6.5 9.1 0.77 9.6 1.1 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated BAF1_ABF1 PF04684.8 CDJ70518.1 - 8 5.1 16.0 12 4.6 11.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor 7TM_transglut PF14402.1 CDJ70519.1 - 0.21 10.5 6.6 0.3 9.9 4.6 1.3 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase G-7-MTase PF12803.2 CDJ70519.1 - 6.4 5.8 11.1 8.8 5.3 7.7 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF2360 PF10152.4 CDJ70520.1 - 4.5 7.5 12.0 4.8 7.4 0.4 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Sec63 PF02889.11 CDJ70521.1 - 8.2e-08 31.8 0.0 1.3e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Sec63 Brl domain YbgS PF13985.1 CDJ70521.1 - 0.22 11.4 2.9 0.37 10.6 2.0 1.3 1 0 0 1 1 1 0 YbgS-like protein T2SF PF00482.18 CDJ70522.1 - 0.039 13.8 1.8 0.066 13.1 1.2 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F GDC-P PF02347.11 CDJ70522.1 - 0.1 11.2 0.3 0.18 10.4 0.2 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein RAB3GAP2_N PF14655.1 CDJ70523.1 - 0.0027 16.7 3.5 0.0027 16.7 2.4 2.2 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.3 CDJ70523.1 - 0.0074 15.6 9.3 0.091 12.1 1.7 2.3 2 0 0 2 2 2 2 Spt20 family SPX PF03105.14 CDJ70523.1 - 0.12 12.1 11.5 0.76 9.5 2.2 2.2 2 0 0 2 2 2 0 SPX domain PAT1 PF09770.4 CDJ70523.1 - 0.28 9.3 44.1 0.064 11.4 10.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SPT6_acidic PF14632.1 CDJ70523.1 - 1.7 8.8 8.6 7.4 6.8 1.9 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 FimP PF09766.4 CDJ70523.1 - 3.6 6.5 29.7 0.063 12.3 5.2 2.6 2 1 0 2 2 2 0 Fms-interacting protein ATAD4 PF15321.1 CDJ70523.1 - 6.8 7.7 12.0 23 6.0 0.8 2.7 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Striatin PF08232.7 CDJ70523.1 - 7.1 6.9 26.7 2.5 8.3 5.1 3.0 2 1 0 2 2 2 0 Striatin family RR_TM4-6 PF06459.7 CDJ70523.1 - 9.1 6.0 15.6 6.9 6.4 3.4 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 IFT57 PF10498.4 CDJ70524.1 - 0.00093 18.0 4.3 0.0014 17.4 3.0 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 CDC37_N PF03234.9 CDJ70524.1 - 0.17 12.2 4.7 0.55 10.5 1.3 2.3 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DUF4200 PF13863.1 CDJ70524.1 - 0.18 11.7 13.0 0.029 14.3 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Retrotrans_gag PF03732.12 CDJ70524.1 - 0.18 11.8 3.1 0.16 12.0 1.0 1.8 1 1 0 1 1 1 0 Retrotransposon gag protein Spc7 PF08317.6 CDJ70524.1 - 0.19 10.3 7.8 0.26 9.9 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.10 CDJ70524.1 - 3.3 7.3 11.9 0.24 11.0 4.7 1.8 2 0 0 2 2 2 0 Mnd1 family Phospholamban PF04272.9 CDJ70525.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Phospholamban WD40 PF00400.27 CDJ70527.1 - 3.7e-18 64.6 9.2 0.028 14.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat HEXIM PF15313.1 CDJ70528.1 - 3.3 7.8 6.7 0.65 10.1 2.2 1.7 2 1 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Ion_trans PF00520.26 CDJ70529.1 - 4.8e-41 140.2 74.6 7.8e-17 61.1 12.8 4.5 4 0 0 4 4 4 4 Ion transport protein Kinesin PF00225.18 CDJ70530.1 - 8.9e-88 294.1 3.8 9.7e-44 149.4 0.0 2.9 2 1 1 3 3 3 2 Kinesin motor domain KIF1B PF12423.3 CDJ70530.1 - 3.6e-05 23.6 0.6 0.0002 21.3 0.1 2.6 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.21 CDJ70530.1 - 0.007 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain DinB PF05163.7 CDJ70530.1 - 6.5 6.4 15.2 0.72 9.5 0.2 3.0 2 1 0 2 2 2 0 DinB family zf-CCHC PF00098.18 CDJ70531.1 - 0.0031 17.3 1.2 0.0031 17.3 0.9 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CDJ70531.1 - 0.014 15.1 0.1 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 CDJ70531.1 - 0.026 14.2 1.8 0.04 13.6 0.1 2.1 2 0 0 2 2 2 0 Zinc knuckle Retrotrans_gag PF03732.12 CDJ70531.1 - 0.1 12.6 0.8 0.23 11.5 0.3 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein DnaJ_CXXCXGXG PF00684.14 CDJ70531.1 - 0.28 11.2 4.4 0.21 11.6 1.3 1.6 1 1 0 1 1 1 0 DnaJ central domain RNase_H PF00075.19 CDJ70532.1 - 0.002 18.4 0.0 0.003 17.9 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 CDJ70532.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like rve PF00665.21 CDJ70533.1 - 9.5e-14 51.5 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDJ70533.1 - 0.024 14.1 0.1 0.081 12.4 0.1 1.9 2 0 0 2 2 2 0 Integrase core domain GLTSCR1 PF15249.1 CDJ70533.1 - 0.096 12.7 0.2 0.3 11.2 0.1 1.9 1 1 1 2 2 2 0 Glioma tumor suppressor candidate region RVT_1 PF00078.22 CDJ70534.1 - 2.5e-21 76.0 0.0 4.8e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 CDJ70534.1 - 1.1e-05 25.5 0.3 3.2e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.18 CDJ70535.1 - 0.0065 16.4 0.1 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GAGA_bind PF06217.7 CDJ70535.1 - 0.087 12.7 14.4 0.13 12.2 10.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SAGA-Tad1 PF12767.2 CDJ70535.1 - 0.094 12.3 19.7 0.11 12.0 13.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SOBP PF15279.1 CDJ70535.1 - 0.15 12.4 17.4 0.16 12.2 12.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein BTV_NS2 PF04514.7 CDJ70535.1 - 0.18 10.6 12.1 0.22 10.3 8.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PAT1 PF09770.4 CDJ70535.1 - 0.28 9.3 51.4 0.33 9.1 35.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 CDJ70535.1 - 0.31 9.5 4.9 0.33 9.4 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4045 PF13254.1 CDJ70535.1 - 0.37 10.0 13.5 0.41 9.8 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SYF2 PF08231.7 CDJ70535.1 - 0.39 10.8 16.4 0.47 10.5 11.3 1.1 1 0 0 1 1 1 0 SYF2 splicing factor Dicty_REP PF05086.7 CDJ70535.1 - 0.64 7.7 10.3 0.72 7.5 7.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein eIF-3_zeta PF05091.7 CDJ70535.1 - 0.79 8.2 21.7 1.1 7.8 15.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.9 CDJ70535.1 - 0.81 9.3 22.5 1 9.0 15.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AUX_IAA PF02309.11 CDJ70535.1 - 0.85 9.3 16.7 1.1 8.9 11.5 1.2 1 0 0 1 1 1 0 AUX/IAA family Lin-8 PF03353.10 CDJ70535.1 - 1.3 8.2 20.0 1.5 7.9 13.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med15 PF09606.5 CDJ70535.1 - 1.6 6.8 64.6 1.8 6.6 44.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 CDJ70535.1 - 1.7 6.2 16.9 1.9 6.0 11.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDJ70535.1 - 2.8 7.7 15.1 3.3 7.5 10.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 CDJ70535.1 - 2.9 7.5 15.2 3.8 7.1 10.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.17 CDJ70535.1 - 3.2 6.6 6.9 4.5 6.1 4.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_UL87 PF03043.9 CDJ70535.1 - 4.6 5.5 9.8 5.3 5.2 6.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Ycf1 PF05758.7 CDJ70535.1 - 5.2 4.6 19.0 6.1 4.4 13.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 CDJ70535.1 - 6.3 5.8 22.1 7.5 5.6 15.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Ndc1_Nup PF09531.5 CDJ70535.1 - 7.9 4.7 16.1 9.1 4.5 11.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rtf2 PF04641.7 CDJ70535.1 - 8.4 5.5 18.4 12 5.0 12.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger SR-25 PF10500.4 CDJ70536.1 - 0.0092 15.4 7.1 0.01 15.3 4.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 CDJ70536.1 - 0.066 13.4 5.0 0.077 13.2 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Corona_nucleoca PF00937.13 CDJ70536.1 - 0.21 10.5 5.1 0.2 10.5 3.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Herpes_capsid PF06112.6 CDJ70536.1 - 0.42 10.6 7.4 0.49 10.4 5.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Spt20 PF12090.3 CDJ70537.1 - 0.00033 20.0 2.6 0.00033 20.0 1.8 2.8 3 0 0 3 3 3 1 Spt20 family LRR19-TM PF15176.1 CDJ70537.1 - 0.0011 18.5 0.7 0.0055 16.3 0.5 2.2 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain DUF4131 PF13567.1 CDJ70537.1 - 0.0076 15.6 1.4 0.0076 15.6 1.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4131) DUF3792 PF12670.2 CDJ70537.1 - 0.46 10.3 3.3 0.49 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) TRP PF06011.7 CDJ70537.1 - 0.52 8.8 5.0 0.19 10.2 0.5 2.2 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel YfhO PF09586.5 CDJ70537.1 - 1.5 6.7 13.1 0.035 12.1 0.9 2.1 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Ribosomal_60s PF00428.14 CDJ70538.1 - 0.014 15.7 9.4 0.014 15.7 6.5 6.8 4 2 1 5 5 5 0 60s Acidic ribosomal protein Transposase_24 PF03004.9 CDJ70538.1 - 0.017 14.9 2.1 0.017 14.9 1.5 3.4 2 1 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) PAP1 PF08601.5 CDJ70538.1 - 1.5 8.4 35.1 0.55 9.8 9.1 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 Macoilin PF09726.4 CDJ70538.1 - 3 6.0 44.0 0.14 10.4 8.1 2.2 2 0 0 2 2 2 0 Transmembrane protein Med3 PF11593.3 CDJ70539.1 - 0.0035 16.6 0.3 0.007 15.6 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal MSP1_C PF07462.6 CDJ70539.1 - 0.11 10.8 2.1 0.17 10.2 1.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RNA_pol_I_TF PF04090.7 CDJ70539.1 - 0.15 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor TGT PF01702.13 CDJ70541.1 - 2.7e-35 121.8 10.5 2.3e-26 92.5 0.0 2.2 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase TMEM51 PF15345.1 CDJ70542.1 - 0.0048 16.6 5.1 0.0057 16.3 3.5 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 KH_1 PF00013.24 CDJ70542.1 - 0.032 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 KH domain ResB PF05140.9 CDJ70542.1 - 0.061 11.8 2.5 0.079 11.4 1.7 1.1 1 0 0 1 1 1 0 ResB-like family KH_3 PF13014.1 CDJ70542.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 KH domain RR_TM4-6 PF06459.7 CDJ70542.1 - 0.12 12.2 11.5 0.12 12.2 7.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SPATIAL PF15256.1 CDJ70542.1 - 0.25 11.3 5.6 0.27 11.2 3.9 1.2 1 0 0 1 1 1 0 SPATIAL Spectrin PF00435.16 CDJ70542.1 - 0.54 10.5 11.6 0.97 9.7 8.0 1.4 1 1 0 1 1 1 0 Spectrin repeat Ycf1 PF05758.7 CDJ70542.1 - 0.59 7.7 8.4 0.63 7.6 5.8 1.0 1 0 0 1 1 1 0 Ycf1 HSP70 PF00012.15 CDJ70542.1 - 0.76 7.6 13.2 0.94 7.3 9.2 1.1 1 0 0 1 1 1 0 Hsp70 protein IncA PF04156.9 CDJ70542.1 - 3.9 7.0 15.1 5.5 6.5 10.5 1.2 1 0 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 CDJ70542.1 - 4 5.5 20.2 5.2 5.2 14.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Fmp27_WPPW PF10359.4 CDJ70542.1 - 4.9 5.4 14.9 6.5 5.0 10.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TTL PF03133.10 CDJ70543.1 - 5.5e-27 94.4 10.0 2.4e-16 59.5 0.0 4.8 4 1 0 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CDJ70543.1 - 8.6e-06 24.7 0.0 8.6e-06 24.7 0.0 4.7 6 2 1 7 7 7 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CDJ70543.1 - 0.0027 17.4 0.2 0.044 13.5 0.0 3.1 3 0 0 3 3 3 1 ATP-grasp domain zf-RING_2 PF13639.1 CDJ70544.1 - 2.5e-13 49.6 4.5 4.1e-13 48.9 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDJ70544.1 - 3.6e-10 39.8 4.1 8.3e-10 38.6 2.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDJ70544.1 - 1.2e-06 28.0 3.9 2.2e-06 27.2 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDJ70544.1 - 1.2e-06 28.4 3.9 2.1e-06 27.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDJ70544.1 - 3.6e-06 26.6 3.1 7.3e-06 25.6 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CDJ70544.1 - 9.3e-06 25.3 0.8 4e-05 23.3 0.5 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CDJ70544.1 - 1.1e-05 25.3 2.6 2.7e-05 24.0 1.8 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 CDJ70544.1 - 4.9e-05 22.9 2.5 8.3e-05 22.1 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 CDJ70544.1 - 0.016 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif RINGv PF12906.2 CDJ70544.1 - 0.067 13.2 4.0 0.15 12.1 2.8 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 CDJ70544.1 - 0.075 12.7 3.1 0.19 11.4 2.2 1.7 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 CDJ70544.1 - 0.1 12.1 1.0 0.19 11.2 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CDJ70544.1 - 0.32 10.6 2.5 0.61 9.7 1.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GAGA_bind PF06217.7 CDJ70544.1 - 0.78 9.6 29.0 0.22 11.4 2.6 3.1 3 0 0 3 3 3 0 GAGA binding protein-like family APC_CDC26 PF10471.4 CDJ70545.1 - 2.1 9.1 23.4 0.63 10.8 3.4 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Spt20 PF12090.3 CDJ70545.1 - 6.1 6.1 13.6 0.54 9.5 0.4 2.1 2 0 0 2 2 2 0 Spt20 family Pro_isomerase PF00160.16 CDJ70547.1 - 3.4e-13 50.0 0.0 7.8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CDJ70547.1 - 5.5e-12 45.1 0.2 5e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ70547.1 - 7.8e-07 28.9 0.0 0.00046 20.1 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDJ70547.1 - 1.2e-05 25.0 0.1 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.14 CDJ70547.1 - 0.00043 20.6 27.3 0.0035 17.7 8.8 4.1 3 1 1 4 4 4 2 60s Acidic ribosomal protein CAF-1_p150 PF11600.3 CDJ70548.1 - 0.0016 17.8 12.0 0.0028 17.0 8.3 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 CDJ70548.1 - 0.19 9.7 4.9 0.18 9.9 3.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_23 PF13476.1 CDJ70548.1 - 0.27 11.5 4.5 0.3 11.3 3.1 1.1 1 0 0 1 1 1 0 AAA domain PH_BEACH PF14844.1 CDJ70548.1 - 0.72 9.7 0.0 0.72 9.7 0.0 2.2 1 1 1 2 2 2 0 PH domain associated with Beige/BEACH Med15 PF09606.5 CDJ70548.1 - 1.2 7.2 24.6 1.2 7.2 17.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tir_receptor_N PF07490.6 CDJ70548.1 - 2.3 7.7 10.0 4.2 6.9 3.6 2.1 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus RED_N PF07808.8 CDJ70548.1 - 4.8 6.3 13.0 10 5.2 9.0 1.6 1 1 0 1 1 1 0 RED-like protein N-terminal region ERF PF04404.7 CDJ70548.1 - 5 6.6 14.4 4.4 6.8 4.6 2.2 2 0 0 2 2 2 0 ERF superfamily SOBP PF15279.1 CDJ70548.1 - 5.1 7.3 14.0 5.8 7.1 9.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein OmpH PF03938.9 CDJ70548.1 - 6.3 6.7 20.8 8.1 6.3 14.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDJ70549.1 - 2.5 6.2 12.2 3.4 5.7 8.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_C54 PF03416.14 CDJ70550.1 - 2.3e-11 43.3 0.0 1.3e-10 40.9 0.0 2.4 1 0 0 1 1 1 1 Peptidase family C54 Ribosomal_S9 PF00380.14 CDJ70551.1 - 1.6e-29 102.6 0.1 1.6e-29 102.6 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S9/S16 tRNA_int_endo_N PF02778.9 CDJ70551.1 - 0.022 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Endonuclease_NS PF01223.18 CDJ70551.1 - 0.51 9.9 4.4 5.2 6.6 0.2 2.2 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease Herpes_UL87 PF03043.9 CDJ70551.1 - 0.64 8.3 4.4 0.88 7.8 3.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Suf PF05843.9 CDJ70552.1 - 0.0013 18.4 16.0 0.0085 15.8 2.7 2.1 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) Serinc PF03348.10 CDJ70552.1 - 0.013 14.2 4.4 0.15 10.7 0.1 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) Sex_peptide PF08138.6 CDJ70552.1 - 0.1 12.4 0.2 0.1 12.4 0.1 2.4 3 0 0 3 3 1 0 Sex peptide (SP) family DDHD PF02862.12 CDJ70552.1 - 0.14 11.9 5.4 1.3 8.7 0.3 2.1 2 0 0 2 2 2 0 DDHD domain FAM176 PF14851.1 CDJ70552.1 - 0.95 9.1 14.0 0.78 9.4 3.2 2.6 2 1 0 2 2 2 0 FAM176 family FHIPEP PF00771.15 CDJ70552.1 - 1.5 7.0 9.0 0.74 8.0 1.3 2.2 2 0 0 2 2 2 0 FHIPEP family PAT1 PF09770.4 CDJ70552.1 - 1.5 6.9 49.8 0.18 10.0 6.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.10 CDJ70552.1 - 4.1 6.6 15.3 0.65 9.2 3.1 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein OATP PF03137.15 CDJ70552.1 - 5.2 4.9 8.3 0.94 7.4 0.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RIC3 PF15361.1 CDJ70552.1 - 7 6.8 19.0 0.46 10.7 3.4 2.5 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 FAM163 PF15069.1 CDJ70552.1 - 7.7 7.0 9.7 0.65 10.5 1.3 2.3 2 0 0 2 2 2 0 FAM163 family SRPRB PF09439.5 CDJ70553.1 - 6e-14 51.6 0.0 6.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CDJ70553.1 - 3.8e-07 29.5 0.0 4.2e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CDJ70553.1 - 1.3e-05 24.6 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CDJ70553.1 - 0.021 14.0 0.0 0.04 13.2 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 CDJ70553.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 Miro-like protein PmbA_TldD PF01523.11 CDJ70555.1 - 0.064 12.5 7.0 0.079 12.2 4.9 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Macoilin PF09726.4 CDJ70555.1 - 0.89 7.7 30.5 1.1 7.4 21.1 1.0 1 0 0 1 1 1 0 Transmembrane protein NnrS PF05940.7 CDJ70555.1 - 1.6 7.5 8.3 0.1 11.5 0.4 1.9 2 0 0 2 2 2 0 NnrS protein SR-25 PF10500.4 CDJ70555.1 - 7.2 6.0 35.6 71 2.7 24.8 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein YliH PF10799.3 CDJ70555.1 - 7.9 6.1 6.5 13 5.5 0.6 2.3 2 0 0 2 2 2 0 Biofilm formation protein (YliH/bssR) Band_3_cyto PF07565.8 CDJ70556.1 - 1.6 8.1 22.6 0.025 14.1 3.9 2.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CRAL_TRIO PF00650.15 CDJ70557.1 - 1.3e-08 34.5 0.0 2.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain AP2 PF00847.15 CDJ70558.1 - 8.8e-10 38.5 0.0 8.8e-10 38.5 0.0 6.1 9 0 0 9 9 9 1 AP2 domain CDC50 PF03381.10 CDJ70559.1 - 3.4e-29 101.8 0.0 1.8e-28 99.4 0.0 2.0 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Acatn PF13000.2 CDJ70560.1 - 8.3e-16 57.6 0.1 2.9e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 SR-25 PF10500.4 CDJ70560.1 - 1.9 7.8 9.7 2.5 7.5 6.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1712 PF08217.6 CDJ70561.1 - 1.5e-15 56.4 0.0 2.6e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Lipocalin_5 PF13924.1 CDJ70561.1 - 0.085 12.5 1.4 0.25 11.0 0.0 2.3 2 1 1 3 3 3 0 Lipocalin-like domain Myc_N PF01056.13 CDJ70561.1 - 3.3 6.7 6.7 1.6 7.8 3.2 1.4 1 1 0 1 1 1 0 Myc amino-terminal region Med15 PF09606.5 CDJ70562.1 - 0.018 13.2 79.4 0.024 12.8 55.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PCEMA1 PF07418.6 CDJ70562.1 - 0.34 10.2 8.1 0.37 10.0 5.6 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 SAGA-Tad1 PF12767.2 CDJ70562.1 - 0.59 9.7 27.0 0.77 9.3 18.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Birna_RdRp PF04197.7 CDJ70562.1 - 0.72 7.8 16.7 0.84 7.5 11.6 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) GAGA_bind PF06217.7 CDJ70562.1 - 0.96 9.3 23.6 1.2 8.9 16.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 CDJ70562.1 - 1.2 8.2 20.9 1.5 8.0 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) XAP5 PF04921.9 CDJ70562.1 - 2.1 7.8 18.0 2.6 7.5 12.5 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Parvo_coat PF00740.13 CDJ70562.1 - 2.2 7.1 24.8 2.6 6.9 17.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Zip PF02535.17 CDJ70562.1 - 3.3 6.6 6.2 4.3 6.2 4.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 CDJ70562.1 - 3.5 6.3 21.5 4.3 6.0 14.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein EIF4E-T PF10477.4 CDJ70562.1 - 4.2 6.0 24.3 4.9 5.8 16.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ycf1 PF05758.7 CDJ70562.1 - 4.5 4.8 24.4 5.5 4.5 16.9 1.0 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDJ70562.1 - 8.2 3.9 27.6 9.7 3.7 19.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.7 CDJ70562.1 - 9.5 4.7 29.9 14 4.1 20.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2146 PF10220.4 CDJ70562.1 - 9.9 3.9 23.3 12 3.6 16.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) LRS4 PF10422.4 CDJ70563.1 - 0.00097 18.5 1.3 0.0012 18.2 0.9 1.2 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 DUF3584 PF12128.3 CDJ70564.1 - 2.3 5.4 23.6 2.8 5.1 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CAS_CSE1 PF03378.10 CDJ70565.1 - 8.5e-37 126.4 10.6 8.5e-37 126.4 7.4 2.9 3 1 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 CDJ70565.1 - 2.7e-33 115.0 1.8 4.9e-30 104.3 0.1 4.8 3 1 0 3 3 3 1 Cse1 IBN_N PF03810.14 CDJ70565.1 - 1.2e-10 41.1 2.5 1.2e-10 41.1 1.7 6.5 8 0 0 8 8 8 1 Importin-beta N-terminal domain Rotamase PF00639.16 CDJ70566.1 - 5.5e-10 39.8 3.1 5.5e-10 39.8 2.1 3.6 1 1 0 2 2 2 1 PPIC-type PPIASE domain CAF-1_p150 PF11600.3 CDJ70566.1 - 0.59 9.4 34.3 0.18 11.1 15.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CT47 PF15623.1 CDJ70566.1 - 2.1 8.0 26.5 1.7 8.3 13.3 2.0 2 0 0 2 2 2 0 Cancer/testis gene family 47 ETRAMP PF09716.5 CDJ70566.1 - 8.8 6.3 6.9 48 4.0 4.8 2.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Cwf_Cwc_15 PF04889.7 CDJ70568.1 - 1e-38 133.4 2.0 1.2e-38 133.2 1.4 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein End3 PF12761.2 CDJ70568.1 - 0.036 13.7 1.4 0.054 13.1 1.0 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 APG6 PF04111.7 CDJ70568.1 - 0.22 10.5 5.5 0.28 10.1 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Erythro_esteras PF05139.9 CDJ70568.1 - 0.57 9.3 10.7 0.87 8.7 7.4 1.2 1 0 0 1 1 1 0 Erythromycin esterase MSP1_C PF07462.6 CDJ70568.1 - 1 7.6 6.3 1.3 7.3 4.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3617 PF12276.3 CDJ70568.1 - 4.9 6.5 6.7 25 4.2 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) SpaB_C PF14028.1 CDJ70568.1 - 5 6.5 15.6 6.4 6.2 10.8 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain Gastrin PF00918.12 CDJ70568.1 - 9.5 7.0 8.3 7.3 7.4 4.4 1.7 1 1 0 2 2 2 0 Gastrin/cholecystokinin family NARP1 PF12569.3 CDJ70569.1 - 0.15 10.8 13.6 0.17 10.6 9.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DevR PF01905.11 CDJ70569.1 - 1.2 7.8 6.3 0.17 10.6 1.5 1.5 1 1 1 2 2 2 0 CRISPR-associated negative auto-regulator DevR/Csa2 Kei1 PF08552.6 CDJ70569.1 - 5.7 6.5 6.1 6.5 6.3 4.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 GAGA_bind PF06217.7 CDJ70569.1 - 5.8 6.7 17.6 6.4 6.6 12.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_DNAp_acc PF04929.7 CDJ70569.1 - 6.8 5.5 15.5 6.9 5.5 10.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDHD PF02862.12 CDJ70569.1 - 7.6 6.2 13.5 8.7 6.0 9.4 1.1 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDJ70569.1 - 7.9 5.0 8.9 7.2 5.2 6.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4557 PF15101.1 CDJ70569.1 - 9.6 5.9 19.6 14 5.4 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDJ70570.1 - 0.14 10.3 12.7 0.15 10.2 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDJ70570.1 - 0.88 7.1 18.5 1.1 6.9 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.3 CDJ70570.1 - 1.2 8.4 6.8 1.6 8.0 4.7 1.2 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDJ70570.1 - 1.7 7.5 9.7 2.3 7.2 6.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein RRP14 PF15459.1 CDJ70570.1 - 1.8 8.6 6.6 3.6 7.7 4.6 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 SR-25 PF10500.4 CDJ70570.1 - 2.3 7.6 19.1 4.8 6.5 13.2 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein FCP1_C PF09309.5 CDJ70570.1 - 6.7 5.9 16.0 12 5.0 11.0 1.4 1 1 0 1 1 1 0 FCP1, C-terminal ADK PF00406.17 CDJ70571.1 - 1.2e-16 60.9 0.0 7.6e-07 29.1 0.0 3.1 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 CDJ70571.1 - 2.5e-05 25.0 0.0 6.7e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDJ70571.1 - 0.00011 22.4 0.0 0.054 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CDJ70571.1 - 0.00019 21.3 3.0 0.0014 18.5 2.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CDJ70571.1 - 9.2 6.1 6.6 1e+02 2.8 4.6 2.1 1 1 0 1 1 1 0 AAA domain p25-alpha PF05517.7 CDJ70572.1 - 4.8e-35 121.0 0.0 7.4e-35 120.4 0.0 1.3 1 1 0 1 1 1 1 p25-alpha RRM_5 PF13893.1 CDJ70573.1 - 1.9e-06 27.5 0.0 4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDJ70573.1 - 8.9e-06 25.5 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDJ70573.1 - 2.6e-05 23.7 0.0 6.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Neur_chan_memb PF02932.11 CDJ70573.1 - 0.11 12.4 0.7 0.66 9.8 0.5 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.8 CDJ70573.1 - 7.3 6.3 21.1 1.3 8.8 1.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PDE6_gamma PF04868.7 CDJ70575.1 - 0.11 12.2 1.6 0.51 10.2 1.1 2.1 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit PH PF00169.24 CDJ70576.1 - 0.0034 17.5 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 PH domain Ribosomal_60s PF00428.14 CDJ70576.1 - 3.4 8.1 17.4 0.82 10.1 1.9 3.3 3 1 0 3 3 3 0 60s Acidic ribosomal protein DUF605 PF04652.11 CDJ70576.1 - 6.1 6.1 16.8 0.19 11.1 6.9 1.8 2 0 0 2 2 2 0 Vta1 like FimP PF09766.4 CDJ70577.1 - 0.0052 15.8 2.9 0.0052 15.8 2.0 3.1 2 1 1 3 3 3 1 Fms-interacting protein Suf PF05843.9 CDJ70577.1 - 0.009 15.7 34.5 0.051 13.2 3.1 2.4 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) GCC2_GCC3 PF07699.8 CDJ70577.1 - 0.021 14.3 2.0 0.05 13.1 1.4 1.7 1 0 0 1 1 1 0 GCC2 and GCC3 DUF966 PF06136.8 CDJ70577.1 - 0.1 11.9 15.2 2.7 7.3 9.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDJ70577.1 - 1.6 8.5 15.1 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF912 PF06024.7 CDJ70577.1 - 3.8 7.6 19.3 0.31 11.1 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RteC PF09357.5 CDJ70578.1 - 0.064 13.1 3.1 0.097 12.5 2.2 1.1 1 0 0 1 1 1 0 RteC protein CRT10 PF08728.5 CDJ70578.1 - 1.1 7.1 13.5 1.4 6.7 9.4 1.0 1 0 0 1 1 1 0 CRT10 Macoilin PF09726.4 CDJ70578.1 - 1.5 6.9 31.2 2.7 6.1 21.6 1.4 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CDJ70578.1 - 1.7 8.4 57.4 0.13 12.1 33.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FimP PF09766.4 CDJ70578.1 - 6.1 5.8 42.8 0.15 11.0 9.0 2.4 3 0 0 3 3 3 0 Fms-interacting protein Hid1 PF12722.2 CDJ70578.1 - 6.6 4.2 29.9 8.8 3.8 20.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_UL87 PF03043.9 CDJ70578.1 - 8.1 4.7 14.3 12 4.1 9.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family Alba PF01918.16 CDJ70579.1 - 2.7e-11 42.8 0.0 3.5e-10 39.3 0.0 2.2 1 1 1 2 2 2 2 Alba Nucleocap_ssRNA PF11128.3 CDJ70579.1 - 0.097 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid Rpp20 PF12328.3 CDJ70579.1 - 4.6 6.8 6.6 0.89 9.2 0.0 2.9 3 1 1 4 4 4 0 Rpp20 subunit of nuclear RNase MRP and P FH2 PF02181.18 CDJ70584.1 - 3.1e-69 233.6 0.3 4.5e-69 233.1 0.2 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Muted PF14942.1 CDJ70584.1 - 0.28 11.0 4.6 9.5 6.0 0.1 2.6 1 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein zf-CCCH PF00642.19 CDJ70585.1 - 3.1e-06 26.7 25.3 0.00033 20.2 1.6 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar)